title: Genomic analysis of the clonal origin and evolution of acute promyelocytic leukemia in a unique patient with a very late (17 years) relapse.
authors.affiliation: Division of Hematology, Department of Medicine, and Center for Molecular Medicine, Karolinska University Hospital Solna and Karolinska Institutet, Stockholm, Sweden.
authors.forename: X
authors.initials: X
authors.lastname: Zhang
authors.affiliation: 1] Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Ministry of Public Health, Qilu Hospital, Shandong University, Jinan, China [2] State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital, Shanghai Jiao Tong University, Shanghai, PR China.
authors.forename: Q
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: Division of Hematology, Department of Medicine, and Center for Molecular Medicine, Karolinska University Hospital Solna and Karolinska Institutet, Stockholm, Sweden.
authors.forename: J
authors.initials: J
authors.lastname: Dahlström
authors.affiliation: Department of Clinical Genetics, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden.
authors.forename: A N
authors.initials: AN
authors.lastname: Tran
authors.affiliation: Computational Intelligence Lab, School of Information Science and Engineering, University of Jinan, Jinan, PR China.
authors.forename: B
authors.initials: B
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital, Shanghai Jiao Tong University, Shanghai, PR China.
authors.forename: Z
authors.initials: Z
authors.lastname: Gu
authors.affiliation: Department of Pathology, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: Ghaderi
authors.affiliation: Department of Pathology, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden.
authors.forename: A
authors.initials: A
authors.lastname: Porwit
authors.affiliation: Department of Microbiology/Key Laboratory for Experimental Teratology of Chinese Ministry of Education, School of Medicine, Shandong University, Jinan, PR China.
authors.forename: J
authors.initials: J
authors.lastname: Jia
authors.affiliation: Division of Hematology, Department of Medicine, and Center for Molecular Medicine, Karolinska University Hospital Solna and Karolinska Institutet, Stockholm, Sweden.
authors.forename: A
authors.initials: A
authors.lastname: Derolf
authors.affiliation: Division of Hematology, Department of Medicine, and Center for Molecular Medicine, Karolinska University Hospital Solna and Karolinska Institutet, Stockholm, Sweden.
authors.forename: D
authors.initials: D
authors.lastname: Xu
authors.affiliation: Division of Hematology, Department of Medicine, and Center for Molecular Medicine, Karolinska University Hospital Solna and Karolinska Institutet, Stockholm, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: Björkholm
mesh_terms: D000328:Adult; D060965:Clonal Evolution; D005260:Female; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000235:genetics*; D015514:Oncogene Proteins, Fusion / Q000032:analysis; D012008:Recurrence
chemical_list: D015514:Oncogene Proteins, Fusion; C093476:promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein