title: KDOQI US commentary on the 2012 KDIGO clinical practice guideline for the evaluation and management of CKD.
abstract: The National Kidney Foundation-Kidney Disease Outcomes Quality Initiative (NKF-KDOQI) guideline for evaluation, classification, and stratification of chronic kidney disease (CKD) was published in 2002. The KDOQI guideline was well accepted by the medical and public health communities, but concerns and criticisms arose as new evidence became available since the publication of the original guidelines. KDIGO (Kidney Disease: Improving Global Outcomes) recently published an updated guideline to clarify the definition and classification of CKD and to update recommendations for the evaluation and management of individuals with CKD based on new evidence published since 2002. The primary recommendations were to retain the current definition of CKD based on decreased glomerular filtration rate or markers of kidney damage for 3 months or more and to include the cause of kidney disease and level of albuminuria, as well as level of glomerular filtration rate, for CKD classification. NKF-KDOQI convened a work group to write a commentary on the KDIGO guideline in order to assist US practitioners in interpreting the KDIGO guideline and determining its applicability within their own practices. Overall, the commentary work group agreed with most of the recommendations contained in the KDIGO guidelines, particularly the recommendations regarding the definition and classification of CKD. However, there were some concerns about incorporating the cause of disease into CKD classification, in addition to certain recommendations for evaluation and management.
authors.affiliation: Tufts Medical Center, Boston, MA. Electronic address: linker@tuftsmedicalcenter.org.
authors.forename: Lesley A
authors.initials: LA
authors.lastname: Inker
authors.affiliation: University of Wisconsin, Madison, WI.
authors.forename: Brad C
authors.initials: BC
authors.lastname: Astor
authors.affiliation: University at Buffalo, Buffalo, NY.
authors.forename: Chester H
authors.initials: CH
authors.lastname: Fox
authors.affiliation: Northwestern University, Chicago, IL.
authors.forename: Tamara
authors.initials: T
authors.lastname: Isakova
authors.affiliation: University of Illinois at Chicago, Chicago, IL.
authors.forename: James P
authors.initials: JP
authors.lastname: Lash
authors.affiliation: University of California, San Francisco, San Francisco, CA.
authors.forename: Carmen A
authors.initials: CA
authors.lastname: Peralta
authors.affiliation: Stanford University School of Medicine, Stanford, CA.
authors.forename: Manjula
authors.initials: M
authors.lastname: Kurella Tamura
authors.affiliation: University of Pennsylvania, Philadelphia, PA.
authors.forename: Harold I
authors.initials: HI
authors.lastname: Feldman
mesh_terms: D019468:Disease Management; D018450:Disease Progression; D005919:Glomerular Filtration Rate; D006801:Humans; D017063:Outcome Assessment, Health Care; D017410:Practice Guidelines as Topic; D051436:Renal Insufficiency, Chronic / Q000628:therapy*
keywords: Estimated glomerular filtration rate (eGFR); Kidney Disease Quality Outcomes Quality Initiative (KDOQI); Kidney Disease: Improving Global Outcomes (KDIGO); albuminuria; chronic kidney diseases (CKD) staging; clinical practice guideline; kidney disease progression