title: Prevalence of dyslipidemia and associated risk factors in Turkish adults.
abstract: OBJECTIVE
  Dyslipidemia is a modifiable major risk factor for coronary heart disease. The objective of this study was to determine the prevalence of dyslipidemia among Turkish adults and its associations with other cardiovascular risk factors.
  
  
  METHODS
  This study included 4309 people ages 20 to 83 years old from 7 provinces of Turkey. People from the city centers, districts, and villages were selected by a stratified sampling method. Weight, height, and waist and hip circumferences were measured. Blood samples were obtained to determine glucose, total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG); these parameters were measured with an autoanalyzer. Dyslipidemia was defined according to National Cholesterol Education Program Adult Treatment Panel III diagnostic criteria.
  
  
  RESULTS
  Of 4309 subjects, 43% had high TC, 41.5% had low HDL-C, 36.2% had high LDL-C, and 35.7% had high TG. Of these measures, at least 1 lipid abnormality was diagnosed in 78.7% of men and 80.4% of women. The prevalence of high TC, LDL-C, and TG increased with age, with the highest prevalence in the 46-to-65-year-old age group. The mean values (mg/dL) of TC, LDL-C, HDL-C, and TG were 194.2 ± 47.7, 117.7 ± 41.1, 50.3 ± 16.3, and 145.4 ± 96.3, respectively. Dyslipidemia was positively associated with age, body mass index, waist circumference, fasting blood glucose, and blood pressure, and negatively associated with altitude.
  
  
  CONCLUSIONS
  The high prevalence of dyslipidemia in Turkey is an important public health problem. Enhanced public health preventive measures should be implemented to better diagnose and comprehensively treat dyslipidemia in Turkey.
authors.affiliation: Faculty of Medicine, Department of Endocrinology and Metabolism, Erciyes University, Kayseri, Turkey.
authors.forename: Fahri
authors.initials: F
authors.lastname: Bayram
authors.affiliation: Department of Biochemistry, Kayseri Research and Training Hospital, Kayseri, Turkey.
authors.forename: Derya
authors.initials: D
authors.lastname: Kocer
authors.affiliation: Faculty of Medicine, Department of Intensive Care, Erciyes University, Kayseri, Turkey.
authors.forename: Kursat
authors.initials: K
authors.lastname: Gundogan
authors.affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Meram Medical Faculty, Selcuk University, Konya, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Kaya
authors.affiliation: Faculty of Medicine, Department of Endocrinology and Metabolism, Ankara University, Ankara, Turkey.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Demir
authors.affiliation: Faculty of Medicine, Department of Intensive Care, Erciyes University, Kayseri, Turkey.
authors.forename: Ramazan
authors.initials: R
authors.lastname: Coskun
authors.affiliation: Faculty of Medicine, Department of Endocrinology and Metabolism, Harran University, Şanlıurfa, Turkey.
authors.forename: Tevfik
authors.initials: T
authors.lastname: Sabuncu
authors.affiliation: Department of Gastroenterology, Kayseri Training and Research Hospital, Kayseri, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Karaman
authors.affiliation: Department of Endocrinology and Metabolic Disease, Ankara Guven Hospital, Ankara, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Cesur
authors.affiliation: BioMedical Department of Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy; Euro-Mediterranean Institute of Science and Technology, Italy.
authors.forename: Manfredi
authors.initials: M
authors.lastname: Rizzo
authors.affiliation: Department of Preventative Cardiology, CGH Medical Center, Sterling, IL; University of Illinois College of Medicine, Peoria, IL. Electronic address: peter.toth@cghmc.com.
authors.forename: Peter P
authors.initials: PP
authors.lastname: Toth
authors.affiliation: Faculty of Medicine, Department of Endocrinology and Metabolism, Ankara University, Ankara, Turkey.
authors.forename: Vedia
authors.initials: V
authors.lastname: Gedik
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D001835:Body Weight; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003327:Coronary Disease / Q000097:blood* / Q000453:epidemiology / Q000473:pathology; D050171:Dyslipidemias / Q000097:blood* / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood; D014421:Turkey / Q000453:epidemiology
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides; D002784:Cholesterol
keywords: Cholesterol; Dyslipidemia; High-density lipoprotein; Low-density lipoprotein; Prevalence; Triglycerides; Turkey