title: [Renal anemia and cardiac remodeling in patients with chronic glomerulonephritis].
abstract: OBJECTIVE
  To study the pattern of cardiac remodeling and its association with anemia in patients with chronic glomerulonephritis (CGN).
  
  
  METHODS
  Sixty patients aged 21 to 58 years (mean age 38.1+9.8 years) with the hypertensive form of CGN were examined. According to the presence of anemia, the patients were divided into 2 groups with 30 persons in each. All the patients underwent physical examination with verification of the diagnosis, estimation of the volume of red blood cells, and echocardiography.
  
  
  RESULTS
  The patients with anemia as compared to those with CGN and without anemia were found to have a statistically significant increase in the left atrial size (3.6 +/- 0.6 cm versus 3.3 +/- 0.3 cm; p < 0.05), left ventricular (LV) end-diastolic size (5.4 +/- 0.6 cm versus 5.1 +/- 0.4 cm; p < 0.05), LV end-systolic size (3.7 +/- 0.7 cm versus 3.3 +/- 0.5 cm; p < 0.05), and LV mass index (141.8 +/- 60.5 g/m2 versus 113.5 +/- 30.8 g/m2; p < 0.05). Correlation analysis revealed statistically significant correlations between red blood cell levels, LV end-systolic and end-diastolic sizes and ejection fraction (EF) in the anemia group while this correlation was absent in the non-anemia group. Group 1 showed a correlation between blood pressure (BP) (mainly diastolic BP), LV sizes and wall thickness.
  
  
  CONCLUSIONS
  The patients with chronic glomerulonephritis complicated with anemia exhibited LV remodeling as LV dilatation.
authors.forename: I T
authors.initials: IT
authors.lastname: Murkamilov
authors.forename: O S
authors.initials: OS
authors.lastname: Lunegova
authors.forename: R R
authors.initials: RR
authors.lastname: Kaliev
mesh_terms: D000328:Adult; D000740:Anemia / Q000150:complications / Q000453:epidemiology / Q000473:pathology*; D064752:Atrial Remodeling / Q000502:physiology; D002908:Chronic Disease; D015897:Comorbidity; D005260:Female; D005921:Glomerulonephritis / Q000150:complications / Q000453:epidemiology / Q000473:pathology*; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000453:epidemiology / Q000473:pathology; D008297:Male; D008875:Middle Aged