title: Water extract of the fungi from Fuzhuan brick tea improves the beneficial function on inhibiting fat deposition.
abstract: Fuzhuan brick tea (FBT) is traditionally consumed by the ethnic group in the border region of northwest China. The unique yellow fungal (Eurotium cristatum) growth phase is considered to be the key process point in the manufacture of the brick tea. The fungi from FBT are not only strongly correlated to the quality of brick tea, but also have the potential function of preventing obesity. The water extract of fungi (100 μg/mL) can significantly inhibit fat deposition in 3T3-L1 adipocyte and Caenorhabditis elegans. Furthermore, the inhibition of 3T3-L1 adipocyte formation was not due to the suppression on cell viability.
authors.affiliation: Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University , Changsha , China .
authors.forename: Yuxuan
authors.initials: Y
authors.lastname: Peng
authors.forename: Zhe
authors.initials: Z
authors.lastname: Xiong
authors.forename: Juan
authors.initials: J
authors.lastname: Li
authors.forename: Jian-An
authors.initials: JA
authors.lastname: Huang
authors.forename: Cuiqin
authors.initials: C
authors.lastname: Teng
authors.forename: Yushun
authors.initials: Y
authors.lastname: Gong
authors.forename: Zhonghua
authors.initials: Z
authors.lastname: Liu
mesh_terms: D016475:3T3 Cells; D017667:Adipocytes / Q000187:drug effects*; D000818:Animals; D017173:Caenorhabditis elegans / Q000187:drug effects; D028241:Camellia sinensis / Q000737:chemistry*; D002454:Cell Differentiation / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D002681:China; D005285:Fermentation; D005658:Fungi / Q000737:chemistry*; D051379:Mice; D009765:Obesity / Q000517:prevention & control; D013662:Tea / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D013662:Tea; D014867:Water
keywords: 3T3-L1 preadipocyte; Caenorhabditis elegans; Eurotium cristatum; Fuzhuan brick tea; fat deposition