title: Resolution of recalcitrant pyogenic granuloma with laser, corticosteroid, and timolol therapy.
abstract: A pyogenic granuloma (PG) is a rapidly growing benign vascular tumor that can be found on the skin or subcutaneous tissue. While some pyogenic granulomas may resolve spontaneously, most have a tendency to bleed easily and require treatment. Current therapeutic modalities include topical imiquimod, cryotherapy, electrodessication, curettage, excision, laser therapy, sclerotherapy, and microembolization. We report a recalcitrant case of chronic pyogenic granuloma occurring on the scalp of a healthy young male which was unresponsive to conventional surgical and non-surgical modalities. Ultimately, aggressive laser therapy, intralesional triamcinolone acetonide injections, and topical timolol application led to complete resolution and healing.
authors.affiliation: California Pacific Medical Center, University of California, Davis. jillian.millsop@gmail.com.
authors.forename: Jillian Wong
authors.initials: JW
authors.lastname: Millsop
authors.forename: Nhat
authors.initials: N
authors.lastname: Trinh
authors.forename: Laura
authors.initials: L
authors.lastname: Winterfield
authors.forename: Ricado
authors.initials: R
authors.lastname: Berrios
authors.forename: Kelli A
authors.initials: KA
authors.lastname: Hutchens
authors.forename: Rebecca
authors.initials: R
authors.lastname: Tung
mesh_terms: D000279:Administration, Cutaneous; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000634:Aminoquinolines / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001706:Biopsy; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination; D017789:Granuloma, Pyogenic / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D006801:Humans; D000077271:Imiquimod; D053685:Laser Therapy; D054025:Lasers, Dye / Q000627:therapeutic use*; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D008297:Male; D012008:Recurrence; D012536:Scalp Dermatoses / Q000188:drug therapy / Q000628:therapy*; D013999:Timolol / Q000627:therapeutic use; D014222:Triamcinolone Acetonide / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D000634:Aminoquinolines; D000900:Anti-Bacterial Agents; D013999:Timolol; D014222:Triamcinolone Acetonide; D000077271:Imiquimod