title: Spontaneous endocarditis caused by rapidly growing non-tuberculous Mycobacterium chelonae in an immunocompetent patient with rheumatic heart disease.
abstract: We are reporting the first case of spontaneous endocarditis caused by rapid grower non-tuberculous Mycobacterium chelonae in a case of rheumatic heart disease. The diagnosis was confirmed as there was repeated isolation of rapidly growing atypical Mycobacterium from blood culture which was identified as M. chelonae by Reverse line probe assay. The patient presented with pyrexia of unknown origin. Later she was found to have rheumatic heart disease with severe aortic regurgitation & large vegetation was seen attached to the aortic valve. She was treated with rifampicin, clarithromycin, amikacin & levofloxacin based on culture & sensitivity. She succumbed to her illness after development of large cerebral infarction due to embolization of vegetation from aortic valve.
authors.affiliation: Department of Microbiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore 560069, Karnataka, India.
authors.forename: Naveena
authors.initials: N
authors.lastname: Jagadeesan
authors.affiliation: Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore 560069, Karnataka, India.
authors.forename: Soumya
authors.initials: S
authors.lastname: Patra
authors.affiliation: Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore 560069, Karnataka, India.
authors.forename: Ajit Pal
authors.initials: AP
authors.lastname: Singh
authors.affiliation: Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore 560069, Karnataka, India.
authors.forename: Chamrajnagar Mahadevappa
authors.initials: CM
authors.lastname: Nagesh
authors.affiliation: Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore 560069, Karnataka, India.
authors.forename: Babu
authors.initials: B
authors.lastname: Reddy
authors.affiliation: Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore 560069, Karnataka, India.
authors.forename: Srinivas C
authors.initials: SC
authors.lastname: Badnur
authors.affiliation: Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore 560069, Karnataka, India.
authors.forename: Manjunath Cholenahally
authors.initials: MC
authors.lastname: Nanjappa
keywords: Aortic valve; Endocarditis; Mycobacterium chelonae; Non-tuberculous mycobacteria; Rheumatic heart disease