title: Nine-year follow-up of children with atopic dermatitis by general practitioners.
abstract: The frequency of associated comorbidity and the cost of treatments in patients with atopic dermatitis (AD) followed up in primary care settings are poorly known. We carried out a retrospective cohort study on a longitudinal electronic medical records database of patients consulting a panel of general practitioners in France. All subjects with AD diagnosed during the first year of life were selected and matched with infants without the disease according to sex (1,163 vs. 1,163). Subjects were followed up for 9 years. Associated diseases, drug consumptions and available medical costs were detailed. Comparisons between subjects and controls were carried out. Subjects with AD had more comorbidities than others, especially in respiratory and ophthalmic system organs. The number of prescribed treatments in the field of skin diseases as well as overall medical costs (general practitioner consultations and prescribed drugs) were higher among atopic subjects, but differences were attenuated with age.
authors.affiliation: Department of Dermatology, University Hospital of Brest, Brest, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Misery
authors.forename: Xavier
authors.initials: X
authors.lastname: Ansolabehere
authors.forename: Nathalie
authors.initials: N
authors.lastname: Grandfils
authors.forename: Victor
authors.initials: V
authors.lastname: Georgescu
authors.forename: Charles
authors.initials: C
authors.lastname: Taieb
mesh_terms: D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D001993:Bronchodilator Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D003876:Dermatitis, Atopic / Q000188:drug therapy* / Q000191:economics / Q000453:epidemiology*; D011307:Drug Prescriptions / Q000191:economics* / Q000706:statistics & numerical data; D004643:Emollients / Q000627:therapeutic use; D005128:Eye Diseases / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D005602:France / Q000453:epidemiology; D058006:General Practice / Q000191:economics* / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D008297:Male; D012140:Respiratory Tract Diseases / Q000188:drug therapy / Q000453:epidemiology*; D012189:Retrospective Studies; D013256:Steroids / Q000627:therapeutic use
chemical_list: D000891:Anti-Infective Agents, Local; D001993:Bronchodilator Agents; D004643:Emollients; D013256:Steroids