title: [The systems of molecular genetic markers under cancer of stomach].
abstract: The study was organized to investigate the anomalous methylation of genes NA?1, RASSF1A, MLH1, N33, DAPK, the expression of genes hTERT. metalloproteinase MMP7, MMP9, survivin. COX-2, p53. The activity of telomerase in 106 samples of stomach tumors taken through intra-operation way and 53 samples of stomach tumors taken through endoscopic way and 50 samples of biopsy taken from patients with chronic calculous cholecystitis (comparison group) was analyzed too. These changes can be used as additional markers both in diagnostic of cancer of stomach and dynamic monitoring of operated patients.
authors.forename: M V
authors.initials: MV
authors.lastname: Nemtsova
authors.forename: I I
authors.initials: II
authors.lastname: Bykov
authors.forename: N V
authors.initials: NV
authors.lastname: Tchekinova
authors.forename: D V
authors.initials: DV
authors.lastname: Zaletaev
authors.forename: A I
authors.initials: AI
authors.lastname: Glikhov
authors.forename: T V
authors.initials: TV
authors.lastname: Khorobrykh
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics*; D001706:Biopsy; D019175:DNA Methylation / Q000235:genetics*; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D011401:Promoter Regions, Genetic; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology
chemical_list: D014408:Biomarkers, Tumor