title: Integrating oxaliplatin with highly luminescent carbon dots: an unprecedented theranostic agent for personalized medicine.
abstract: A theranostic nanomedicine (CD-Oxa) is synthesized by means of the condensation reaction between the amino groups on the surface of fluorescent carbon dots (CDs) and the carboxyl group of the oxaliplatin derivative Oxa(IV)-COOH. CD-Oxa, which integrates the optical properties of CDs and the anticancer function of oxaliplatin, could be used for simultaneous drug delivery and fluorescent tracking.
authors.affiliation: State Key Laboratory of Luminescence and Applications, Changchun Institute of OpticsFine Mechanics and Physics, Chinese Academy of Sciences, 3888 East Nanhu Road, Changchun, Jilin, 130033, P. R. China.
authors.forename: Min
authors.initials: M
authors.lastname: Zheng
authors.forename: Shi
authors.initials: S
authors.lastname: Liu
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Dan
authors.initials: D
authors.lastname: Qu
authors.forename: Haifeng
authors.initials: H
authors.lastname: Zhao
authors.forename: Xingang
authors.initials: X
authors.lastname: Guan
authors.forename: Xiuli
authors.initials: X
authors.lastname: Hu
authors.forename: Zhigang
authors.initials: Z
authors.lastname: Xie
authors.forename: Xiabin
authors.initials: X
authors.lastname: Jing
authors.forename: Zaicheng
authors.initials: Z
authors.lastname: Sun
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D017554:Carbon Compounds, Inorganic / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D002460:Cell Line; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D016903:Drug Monitoring / Q000379:methods; D005347:Fibroblasts / Q000187:drug effects; D005453:Fluorescence; D006367:HeLa Cells; D056945:Hep G2 Cells; D006801:Humans; D051379:Mice; D050997:Nanomedicine / Q000379:methods; D061848:Optical Imaging / Q000379:methods; D009944:Organoplatinum Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D000077150:Oxaliplatin; D010316:Particle Size; D057285:Precision Medicine / Q000379:methods; D045663:Quantum Dots / Q000737:chemistry* / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D017554:Carbon Compounds, Inorganic; D009944:Organoplatinum Compounds; D000077150:Oxaliplatin
keywords: bioimaging; bionanotechnology; carbon nanoparticles; oxaliplatin; personalized medicine; theranostics