title: UK Renal Registry 16th annual report: chapter 13 clinical, haematological and biochemical parameters in patients receiving renal replacement therapy in paediatric centres in the uk in 2012: national and centre-specific analyses.
abstract: BACKGROUND
  The British Association for Paediatric Nephrology Registry (BAPN) was established to analyse data related to renal replacement therapy (RRT) in children. The registry receives data from the 13 paediatric nephrology centres in the UK. This chapter aims to provide centre specific data so that individual centres can reflect on the contribution that their data makes to the national picture and to determine the extent to which their patient parameters meet nationally agreed audit standards for the management of children with established renal failure (ERF).
  
  
  METHODS
  Data returns included a mixture of electronic (92%) and paper (8%) returns. Data were analysed to calculate summary statistics and where applicable the percentage achieving an audit standard. The standards used were those set out by the Renal Association and the National Institute for Health and Clinical Excellence.
  
  
  RESULTS
  Anthropometric data confirmed that children receiving RRT were short compared to healthy peers. Amongst patients with a height of <2SD between 2001 and 2012, 29.2%were receiving growth hormone if they were on dialysis compared to 11.9% if they had a functioning transplant. Prevalence rates of overweight and obese status in children with ERF remain concerningly high. Blood pressure control remained challenging with wide inter-centre variation although this was significantly better in children with a functioning transplant. Over a quarter of haemodialysis patients and 17.3% of peritoneal dialysis patients were anaemic, compared to only 8.3% of transplanted patients. ESA use in the dialysis population exceeded 90% amongst anaemic patients. The control of renal bone disease remained challenging.
  
  
  CONCLUSIONS
  Optimising growth and reducing prevalent excess weight in children on RRT remains challenging. The likelihood of complete electronic reporting in the near future with plans for quarterly reporting in the format of the recently finalised NEW paediatric dataset will hopefully improve quality of data and their reporting, allowing improvements in patient care.
authors.affiliation: UK Renal Registry, Bristol, UK.
authors.forename: Rishi
authors.initials: R
authors.lastname: Pruthi
authors.forename: Heather
authors.initials: H
authors.lastname: Maxwell
authors.forename: Anna
authors.initials: A
authors.lastname: Casula
authors.forename: Fiona
authors.initials: F
authors.lastname: Braddon
authors.forename: Malcolm
authors.initials: M
authors.lastname: Lewis
authors.forename: Catherine
authors.initials: C
authors.lastname: O'Brien
authors.forename: Jelena
authors.initials: J
authors.lastname: Stojanovic
authors.forename: Yincent
authors.initials: Y
authors.lastname: Tse
authors.forename: Carol
authors.initials: C
authors.lastname: Inward
authors.forename: Manish D
authors.initials: MD
authors.lastname: Sinha
mesh_terms: D000293:Adolescent; D000740:Anemia / Q000453:epidemiology; D000847:Annual Reports as Topic; D001639:Bicarbonates / Q000097:blood; D001794:Blood Pressure; D001827:Body Height; D015992:Body Mass Index; D002118:Calcium / Q000097:blood; D002391:Catchment Area, Health / Q000706:statistics & numerical data; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004921:Erythropoietin / Q000097:blood; D005919:Glomerular Filtration Rate; D013006:Growth Hormone / Q000627:therapeutic use; D019983:Guideline Adherence / Q000706:statistics & numerical data; D006397:Hematinics / Q000627:therapeutic use; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007676:Kidney Failure, Chronic / Q000097:blood / Q000453:epidemiology / Q000628:therapy*; D016030:Kidney Transplantation / Q000592:standards / Q000706:statistics & numerical data*; D008137:Longitudinal Studies; D009765:Obesity / Q000453:epidemiology*; D010281:Parathyroid Hormone / Q000097:blood; D010710:Phosphates / Q000097:blood; D017410:Practice Guidelines as Topic; D015995:Prevalence; D012042:Registries / Q000706:statistics & numerical data*; D006435:Renal Dialysis / Q000592:standards / Q000706:statistics & numerical data*; D006113:United Kingdom / Q000453:epidemiology
chemical_list: D001639:Bicarbonates; D006397:Hematinics; D006454:Hemoglobins; D010281:Parathyroid Hormone; D010710:Phosphates; D004921:Erythropoietin; D013006:Growth Hormone; D002118:Calcium