title: Epilepsy surgery in pediatric intractable epilepsy with destructive encephalopathy.
abstract: OBJECTIVE
  The aim of the current study is to review the clinical features, surgery outcomes and parental satisfaction of children with destructive encephalopathy who underwent epilepsy surgery due to medically intractable seizures.
  
  
  METHODS
  48 patients who underwent epilepsy surgery from October 2003 to August 2011 at Severance Children's Hospital have been reviewed. The survey was conducted for functional outcomes and parental satisfaction at least 1 year after the surgery.
  
  
  RESULTS
  Epileptic encephalopathy including Lennox-Gastaut syndrome and infantile spasms was more prevalent than symptomatic focal epilepsy. Hypoxic ischemic injury accounted for most of the underlying etiology of the destructive encephalpathy, followed by central nervous system infection and head trauma. 27 patients (56.3%) underwent resective surgery and 21 patients (43.7%) underwent palliative surgery. 16 patients (33.3%) achieved seizure free and 27 parents (87.5%) reported satisfaction with the outcome of their children's epilepsy surgery. In addition, 14 parents (77.8 %) whose children were not seizure free reported satisfaction with their children's improvement in cognitive and behavior issues.
  
  
  CONCLUSIONS
  Epilepsy surgery in destructive encephalopathy was effective for controlling seizures. Parents reported satisfaction not only with the surgical outcomes, but also with improvement of cognitive and behavior issues.
authors.affiliation: Department of Pediatric Neurology, Pediatric Epilepsy Clinics, Severance Children's Hospital, Epilepsy Research Institute, Yonsei University College of Medicine;
authors.forename: So Young
authors.initials: SY
authors.lastname: Park
authors.affiliation: Department of Pediatrics, Gangnam Severance Hospital, Yonsei University College of Medicine;
authors.forename: Hye Eun
authors.initials: HE
authors.lastname: Kwon
authors.affiliation: Department of Pediatric Neurology, Pediatric Epilepsy Clinics, Severance Children's Hospital, Epilepsy Research Institute, Yonsei University College of Medicine;
authors.forename: Hoon-Chul
authors.initials: HC
authors.lastname: Kang
authors.affiliation: Department of Pediatric Neurology, Pediatric Epilepsy Clinics, Severance Children's Hospital, Epilepsy Research Institute, Yonsei University College of Medicine;
authors.forename: Joon Soo
authors.initials: JS
authors.lastname: Lee
authors.affiliation: Division of Pediatric Neurosurgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Dong Seok
authors.initials: DS
authors.lastname: Kim
authors.affiliation: Department of Pediatric Neurology, Pediatric Epilepsy Clinics, Severance Children's Hospital, Epilepsy Research Institute, Yonsei University College of Medicine;
authors.forename: Heung Dong
authors.initials: HD
authors.lastname: Kim
keywords: Destructive encephalopathy; Epilepsy surgery; Intractable epilepsy