title: Magnetic Resonance Image findings of Spinal Tuberclosis at first presentation.
abstract: BACKGROUND
  Spinal tuberculosis presents in various pathological patterns. The clinical presentation and often the management depend on exact pathological findings. Objective of study was to evaluate the Pathology of spinal tuberculosis as depicted by MRI findings in 119 consecutive cases of spinal TB.
  
  
  METHODS
  It was a cross sectional and observational study conducted at Civil Hospital, Karachi from July 2010 to December 2012.Total numbers of participants were 119. Diagnosis was based on positive histopathology results along with the supportive evidence in MRI. A pre-structured questionnaire was constructed to record the data. Study was ethically approved by Institutional Review Board of Dow University of Health Sciences. Sample size was calculated by using Open-EPI software. All the data was entered and analyzed through SPSS 19.
  
  
  RESULTS
  There were 119 patients who participated in this study out of which 52 were males and 67 were females. Most common level was Dorso-lumbar (33.6%) and 87.5% of them had spondylodiscitis while 90% had cord compression. All 6 (100%) patients who had their upper- dorsal region affected had gibbus formation while all those patients having lumbosacral region involved had thecal compression 4 (100%). Most common mode of treatment used in patients having Spinal TB at Lumbar region was conservative (86.2%).
  
  
  CONCLUSIONS
  MRI findings were mostly shadowed with features such as disc destruction and thecal or cord compression. MRI scan could be used for early detection of spinal TB which can reduce disability and deaths in patients. Major clinical findings in spinal TB were fever, Para paresis and back pain.
authors.forename: Arsalan Ahmad
authors.initials: AA
authors.lastname: Alvi
authors.forename: Aisha
authors.initials: A
authors.lastname: Raees
authors.forename: Muhammad Asim
authors.initials: MA
authors.lastname: Khan Rehmani
authors.affiliation: Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan. coolaslam8@hotmail.com.
authors.forename: Hafiz Muhammad
authors.initials: HM
authors.lastname: Aslam
authors.forename: Shafaq
authors.initials: S
authors.lastname: Saleem
authors.forename: Junaid
authors.initials: J
authors.lastname: Ashraf