title: Salmonella subtypes with increased MICs for azithromycin in travelers returned to The Netherlands.
abstract: Antimicrobial susceptibility was analyzed for 354 typhoidal Salmonella isolates collected during 1999-2012 in the Netherlands. In 16.1% of all isolates and in 23.8% of all isolates that showed increased MICs for ciprofloxacin, the MIC for azithromycin was increased. This resistance may complicate empirical treatment of enteric fever.
authors.forename: Robert-Jan
authors.initials: RJ
authors.lastname: Hassing
authors.forename: Wil H F
authors.initials: WH
authors.lastname: Goessens
authors.forename: Wilfrid
authors.initials: W
authors.lastname: van Pelt
authors.forename: Dik J
authors.initials: DJ
authors.lastname: Mevius
authors.forename: Bruno H
authors.initials: BH
authors.lastname: Stricker
authors.forename: Nicky
authors.initials: N
authors.lastname: Molhoek
authors.forename: Annelies
authors.initials: A
authors.lastname: Verbon
authors.forename: Perry J J
authors.initials: PJ
authors.lastname: van Genderen
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017963:Azithromycin / Q000627:therapeutic use*; D002939:Ciprofloxacin / Q000627:therapeutic use; D024881:Drug Resistance, Bacterial / Q000502:physiology; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods; D009426:Netherlands; D012475:Salmonella / Q000187:drug effects* / Q000302:isolation & purification*; D012480:Salmonella Infections / Q000188:drug therapy* / Q000382:microbiology; D014195:Travel; D014435:Typhoid Fever / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin; D017963:Azithromycin
keywords: Salmonella; azithromycin; bacteria; cephalosporin; drug resistance; enteric fever; fluoroquinolone; paratyphi; the Netherlands; travel medicine; typhi; typhoid