title: Oral lichen planus and lichenoid mucositis.
abstract: Oral lichen planus (OLP) is commonly found in middle-aged women. Although the cause is unknown, research points to several complex immunologic events and cells that are responsible for the inflammatory destruction and chronicity of these lesions. Biopsy for histologic diagnosis is recommended. The mainstay of treatment remains topical corticosteroids; however, newer therapies such as immunomodulating agents are available for recalcitrant lesions. In cases of lichenoid mucositis or reactions, treatment should be directed at identifying and removing the presumed cause. Given the apparent risk of squamous cell carcinoma in these patients, frequent follow-up and repeat biopsy are vital.
authors.affiliation: Department of Oral Health and Diagnostic Sciences, College of Dental Medicine, Georgia Regents University, 1120 15th Street, Augusta, GA 30912, USA; Department of Otolaryngology/Head & Neck Surgery, Medical College of Georgia, Georgia Regents University, 1120 15th Street, Augusta, GA 30912, USA; Department of Dermatology, Medical College of Georgia, Georgia Regents University, 1120 15th Street, Augusta, GA 30912, USA. Electronic address: SDEROSSI@gru.edu.
authors.forename: Scott S
authors.initials: SS
authors.lastname: De Rossi
authors.affiliation: Department of Oral Rehabilitation, College of Dental Medicine, Georgia Regents University, 1120 15th Street, Augusta, GA 30912, USA.
authors.forename: Katharine
authors.initials: K
authors.lastname: Ciarrocca
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001706:Biopsy / Q000379:methods; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D017676:Lichen Planus, Oral / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D017512:Lichenoid Eruptions / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D009062:Mouth Neoplasms / Q000175:diagnosis; D011230:Precancerous Conditions / Q000175:diagnosis; D013280:Stomatitis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
chemical_list: D000305:Adrenal Cortex Hormones; D007155:Immunologic Factors
keywords: Lichen planus; Lichenoid drug reaction; Lichenoid mucositis; Oral lichen planus