title: A new 2-(2-phenylethyl)chromone derivative in Chinese agarwood 'Qi-Nan' from Aquilaria sinensis.
abstract: Phytochemical analysis of the high quality Chinese agarwood 'Qi-Nan' originating from Aquilaria sinensis (Lour.) Glig led to the isolation of a new 2-(2-phenylethyl)chromone derivative, qinanones G (1), and four known 2-(2-phenylethyl)chromones (2-5). Their structures were elucidated by spectroscopic techniques (UV, IR, 1D and 2D NMR) and MS analyses. The NMR data of chromones 1-3 were first reported, and chromones 2 and 3 showed weak inhibitory activity against acetylcholinesterase.
authors.affiliation: a Horticultural and Garden College, Hainan University , Haikou 570228 , China.
authors.forename: De-Lan
authors.initials: DL
authors.lastname: Yang
authors.forename: Hao
authors.initials: H
authors.lastname: Wang
authors.forename: Zhi-Kai
authors.initials: ZK
authors.lastname: Guo
authors.forename: Wen-Hua
authors.initials: WH
authors.lastname: Dong
authors.forename: Wen-Li
authors.initials: WL
authors.lastname: Mei
authors.forename: Hao-Fu
authors.initials: HF
authors.lastname: Dai
mesh_terms: D002800:Cholinesterase Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002867:Chromones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D029645:Thymelaeaceae / Q000737:chemistry*
chemical_list: D002800:Cholinesterase Inhibitors; D002867:Chromones; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; C000592304:qinanone G; C062550:2-(2-phenylethyl)chromone
keywords: 2-(2-phenylethyl)chromone derivative; AChE inhibitory activity; Aquilaria sinensis; Qi-Nan; agarwood