title: Preoperative prediction of the extrathyroidal extension of papillary thyroid carcinoma with ultrasonography versus MRI: a retrospective cohort study.
abstract: BACKGROUND
  The purpose of this study was to assess the diagnostic performance of preoperative ultrasonography (US) for the prediction of extrathyroidal extension (ETE) in patients with papillary thyroid carcinoma (PTC) and to compare the diagnostic performances of US and magnetic resonance imaging (MRI) for predicting ETE.
  
  
  METHODS
  75 patients with PTC who underwent preoperative US and MRI were retrospectively reviewed in this study. Two radiologists independently evaluated the US and MR findings to assess minimal or extensive ETE of PTC. These results were compared with the histopathologic findings. The diagnostic performances of US and MRI in the evaluation of ETE were compared.
  
  
  RESULTS
  US was more accurate than MRI in the prediction of minimal ETE (p < 0.05) and the accuracies were not significantly different between US and MRI in extensive ETE. US showed higher sensitivity, negative predictive value and accuracy than MRI (p < 0.001) in the prediction of overall ETE.
  
  
  CONCLUSIONS
  US provided higher accuracy for assessing overall ETE and higher sensitivity for minimal ETE than MR imaging in preoperative evaluation of ETE of PTC. There was no significant difference in evaluating extensive ETE of PTC between US and MRI.
authors.affiliation: Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211, Eonjuro, Gangnam-Gu, Seoul 135-720, South Korea.
authors.forename: Hana
authors.initials: H
authors.lastname: Kim
authors.affiliation: Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211, Eonjuro, Gangnam-Gu, Seoul 135-720, South Korea. Electronic address: chrismd@hanmail.net.
authors.forename: Jeong-Ah
authors.initials: JA
authors.lastname: Kim
authors.affiliation: Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211, Eonjuro, Gangnam-Gu, Seoul 135-720, South Korea.
authors.forename: Eun Ju
authors.initials: EJ
authors.lastname: Son
authors.affiliation: Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211, Eonjuro, Gangnam-Gu, Seoul 135-720, South Korea.
authors.forename: Ji Hyun
authors.initials: JH
authors.lastname: Youk
authors.affiliation: Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211, Eonjuro, Gangnam-Gu, Seoul 135-720, South Korea.
authors.forename: Tae-Sub
authors.initials: TS
authors.lastname: Chung
authors.affiliation: Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Cheong Soo
authors.initials: CS
authors.lastname: Park
authors.affiliation: Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Hang-Seok
authors.initials: HS
authors.lastname: Chang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D002291:Carcinoma, Papillary; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011300:Preoperative Care; D012189:Retrospective Studies; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D014463:Ultrasonography; D055815:Young Adult
keywords: Imaging; Magnetic resonance imaging; Papillary thyroid carcinoma; Sensitivity; Tumor staging; Ultrasound