title: Treatment of infectious disease: beyond antibiotics.
abstract: Several antibiotics have been discovered following the discovery of penicillin. These antibiotics had been helpful in treatment of infectious diseases considered dread for centuries. The advent of multiple drug resistance in microbes has posed new challenge to researchers. The scientists are now evaluating alternatives for combating infectious diseases. This review focuses on major alternatives to antibiotics on which preliminary work had been carried out. These promising anti-microbial include: phages, bacteriocins, killing factors, antibacterial activities of non-antibiotic drugs and quorum quenching.
authors.affiliation: IPLS Building, School of Life Science, Pondicherry University, Puducherry 605014, India. Electronic address: anshulnigam2006@gmail.com.
authors.forename: Anshul
authors.initials: A
authors.lastname: Nigam
authors.affiliation: Department of Biotechnology, Mangalayatan University, Beswan, Aligarh, Uttar Pradesh 202145, India.
authors.forename: Divya
authors.initials: D
authors.lastname: Gupta
authors.affiliation: Computer-Chemie-Centrum, Universität Erlangen-Nürnberg, Nägelsbachstr. 25, 91052 Erlangen, Germany.
authors.forename: Ashwani
authors.initials: A
authors.lastname: Sharma
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001691:Biological Therapy / Q000379:methods*; D003141:Communicable Diseases / Q000628:therapy*; D004351:Drug Resistance; D006801:Humans
chemical_list: D000900:Anti-Bacterial Agents
keywords: Bacteriocins; Killing factors; Non-antibiotic drugs; Phages; Quorum quenching