title: A study on the effect of resveratrol on lipid metabolism in hyperlipidemic mice.
abstract: BACKGROUND
  The content of resveratrol is relatively high in Polygonum cuspidatum Sieb. et Zucc., and the resveratrol has the effect of blood vessel dilating, microcirculation improving, platelet aggregation inhibiting and anti-cancer. The objective of this paper was to study the effect of resveratrol on lipid metabolism in hyperlipidemia mice.
  
  
  METHODS
  Through the establishment of an experimental mouse model of hyperlipidemia, the effect of resveratrol on change in total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-c), and low-density lipoprotein cholesterol (LDL-c) levels in mouse serum were determined.
  
  
  RESULTS
  Resveratrol group can apparently reduce TC, TG, LDL-c and AI of hyperlipidemic mice in a dose effect manner.
  
  
  CONCLUSIONS
  We concluded that resveratrol can effectively reduce blood lipid levels of hyperlipidemic mice.
authors.affiliation: The Key Laboratory of Education Ministry on Environments and Resources in Tibetan Plateau, Qinghai-Normal University, 38 West Wusi Road, Xining, 810008 ; Shaanxi Normal University, 199 South Chang'an Road, Xi'an, 710062.
authors.forename: Hui-chun
authors.initials: HC
authors.lastname: Xie
authors.affiliation: The Key Laboratory of Education Ministry on Environments and Resources in Tibetan Plateau, Qinghai-Normal University, 38 West Wusi Road, Xining, 810008 ; Shaanxi Normal University, 199 South Chang'an Road, Xi'an, 710062.
authors.forename: Hong-Ping
authors.initials: HP
authors.lastname: Han
authors.affiliation: The Key Laboratory of Education Ministry on Environments and Resources in Tibetan Plateau, Qinghai-Normal University, 38 West Wusi Road, Xining, 810008.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Chen
authors.affiliation: Shaanxi Normal University, 199 South Chang'an Road, Xi'an, 710062.
authors.forename: Jian-Ping
authors.initials: JP
authors.lastname: He
mesh_terms: D000818:Animals; D001161:Arteriosclerosis / Q000097:blood / Q000517:prevention & control; D002784:Cholesterol / Q000097:blood*; D004305:Dose-Response Relationship, Drug; D045468:Fallopia japonica / Q000737:chemistry*; D006949:Hyperlipidemias / Q000097:blood / Q000188:drug therapy*; D050356:Lipid Metabolism / Q000187:drug effects; D008297:Male; D051379:Mice; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D000077185:Resveratrol; D013267:Stilbenes / Q000494:pharmacology / Q000627:therapeutic use*; D014280:Triglycerides / Q000097:blood*
chemical_list: D010936:Plant Extracts; D013267:Stilbenes; D014280:Triglycerides; D002784:Cholesterol; D000077185:Resveratrol
keywords: HDL-c; LDL-c; Resveratrol; TC; TG; hyperlipidemia