title: A novel GyrB mutation in meticillin-resistant Staphylococcus aureus (MRSA) confers a high level of resistance to third-generation quinolones.
authors.affiliation: Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
authors.forename: Hidemasa
authors.initials: H
authors.lastname: Nakaminami
authors.affiliation: Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
authors.forename: Koko
authors.initials: K
authors.lastname: Sato-Nakaminami
authors.affiliation: Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan. Electronic address: noguchin@toyaku.ac.jp.
authors.forename: Norihisa
authors.initials: N
authors.lastname: Noguchi
mesh_terms: D019943:Amino Acid Substitution; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D027081:DNA Gyrase / Q000235:genetics*; D024881:Drug Resistance, Bacterial; D005838:Genotype; D006761:Hospitals; D006801:Humans; D007564:Japan; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D050505:Mutant Proteins / Q000235:genetics; D020125:Mutation, Missense; D015363:Quinolones / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D050505:Mutant Proteins; D015363:Quinolones; D027081:DNA Gyrase