title: Clec12a: quieting the dead.
abstract: Immune activation as a result of the recognition of damage-associated molecular patterns needs to be controlled. In this issue of Immunity, Neumann et al. (2014) demonstrates that Clec12a is a receptor for dead cells through the recognition of uric acid crystals and contributes to the dampening of the responses.
authors.affiliation: Division of Molecular Immunology, Research Center for Infectious Diseases, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi Higashiku, Fukuoka 812-8582, Japan. Electronic address: yamasaki@bioreg.kyushu-u.ac.jp.
authors.forename: Sho
authors.initials: S
authors.lastname: Yamasaki
mesh_terms: D000818:Animals; D016923:Cell Death; D007249:Inflammation / Q000378:metabolism*; D037181:Lectins, C-Type / Q000378:metabolism*; D011975:Receptors, Mitogen / Q000378:metabolism*; D014527:Uric Acid / Q000378:metabolism*
chemical_list: C529398:CLEC12A protein, mouse; D037181:Lectins, C-Type; D011975:Receptors, Mitogen; D014527:Uric Acid