title: The role of monoacylglycerol lipase (MAGL) in the cancer progress.
abstract: In recent years, metabolism is talked highly important in cancer research, especially the lipid metabolism. Researchers believe that the de novo fatty acid synthesis plays an important role in tumor development, while many studies illustrated that Endocannabinoids have anti-tumorigenic actions, including anti-proliferation, apoptosis induction, and anti-metastatic effects, MAGL as an important decomposing enzyme of both lipid metabolism and endocannabinoids system, additionally as a part of a gene expression signature contributes to different aspects of tumourigenesis.
authors.affiliation: Department of Oncology, Southwest Hospital, The Third Military Medical University, Chongqing, 400038, People's Republic of China.
authors.forename: Hong
authors.initials: H
authors.lastname: Qin
authors.forename: Zhi-hua
authors.initials: ZH
authors.lastname: Ruan
mesh_terms: D018450:Disease Progression; D063388:Endocannabinoids / Q000378:metabolism; D006801:Humans; D050356:Lipid Metabolism; D008994:Monoacylglycerol Lipases / Q000378:metabolism*; D009369:Neoplasms / Q000201:enzymology* / Q000378:metabolism
chemical_list: D063388:Endocannabinoids; D008994:Monoacylglycerol Lipases