title: Development of monetite-nanosilica bone cement: a preliminary study.
abstract: In this paper, we reported the results of our efforts in developing DCPA/nanosilica composite orthopedic cement. It is motivated by the significances of DCPA and silicon in bone physiological activities. More specifically, this paper examined the effects of various experimental parameters on the properties of such composite cements. In this work, DCPA cement powders were synthesized using a microwave synthesis technique. Mixing colloidal nanosilica directly with synthesized DCPA cement powders can significantly reduce the washout resistance of DCPA cement. In contrast, a DCPA-nanosilica cement powder prepared by reacting Ca(OH)2 , H3 PO4 and nanosilica together showed good washout resistance. The incorporation of nanosilica in DCPA can improve compressive strength, accelerate cement solidification, and intensify surface bioactivity. In addition, it was observed that by controlling the content of NaHCO3 during cement preparation, the resulting composite cement properties could be modified. Allowing for the development of different setting times, mechanical performance and crystal features. It is suggested that DCPA-nanosilica composite cement can be a potential candidate for bone healing applications.
authors.affiliation: Institute of Biomedical Engineering and Health Sciences, Changzhou University, Changzhou, Jiangsu, China; Department of Mechanical Industrial and Manufacturing Engineering, The University of Toledo, Toledo, Ohio.
authors.forename: Huan
authors.initials: H
authors.lastname: Zhou
authors.forename: Timothy J F
authors.initials: TJ
authors.lastname: Luchini
authors.forename: Anand K
authors.initials: AK
authors.lastname: Agarwal
authors.forename: Vijay K
authors.initials: VK
authors.lastname: Goel
authors.forename: Sarit B
authors.initials: SB
authors.lastname: Bhaduri
mesh_terms: D001843:Bone Cements / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry*; D019245:Compressive Strength; D008422:Materials Testing; D049329:Nanostructures / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: D001843:Bone Cements; D002130:Calcium Phosphates; D012822:Silicon Dioxide; C485829:calcium phosphate, dibasic, anhydrous
keywords: cement; microwave; monetite; nanosilica