title: Diagnosis and management of morphea and lichen sclerosus and atrophicus in children.
abstract: Morphea (localized scleroderma) is a rare fibrosing disorder of the skin and underlying tissues characterized by skin thickening and hardening due to increased collagen deposition. The significance of the disease depends on the extent of the lesions, potential for functional disability or cosmetic disfigurement, and presence or absence of extracutaneous manifestations. Treatment is tailored; circumscribed forms may require only topical treatment, while forms causing functional impairment or severe cosmetic change may require systemic treatment. Although localized scleroderma has a good prognosis, some clinical subtypes can be deforming and irreversibly disabling, especially when affecting the extremities or the face.
authors.affiliation: Section of Dermatology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON M5G 1X8, Canada. Electronic address: elena.pope@sickkids.ca.
authors.forename: Elena
authors.initials: E
authors.lastname: Pope
authors.affiliation: Departments of Paediatrics and Medicine, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON M5G 1X8, Canada.
authors.forename: Ronald M
authors.initials: RM
authors.lastname: Laxer
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D006801:Humans; D018459:Lichen Sclerosus et Atrophicus / Q000175:diagnosis* / Q000628:therapy; D012594:Scleroderma, Localized / Q000175:diagnosis* / Q000628:therapy
keywords: Atrophoderma of Pasini and Pierini; En coup de sabre; Lichen sclerosus et atrophicus; Localized scleroderma; Morphea; Parry-Romberg syndrome