title: [Side effects of drugs on the oral cavity].
abstract: Although drugs are the most powerful therapeutic tools we have for improving the quality of life of the population, their use is not free of adverse effects. Today there are many polymedicated patients, and it is difficult to find the cause of their adverse effects that increase exponentially when more than 4 drugs are combined. There are a large number of drugs that can result in numerous adverse effects in the oral cavity. The most common are xerostomia, altered taste, gingival enlargement and mucositis caused by cancer treatment. We also review other disorders of the salivary glands, oral mucosal changes, pigmentations, halitosis, osteonecrosis, opportunistic infections and bleeding diathesis.
authors.affiliation: Departamento de Medicina y Cirugía Bucofacial, Facultad de Odontología, Universidad Complutense de Madrid, Madrid, España. Electronic address: antbasco@odon.ucm.es.
authors.forename: Antonio
authors.initials: A
authors.lastname: Bascones-Martínez
authors.affiliation: Departamento de Medicina y Cirugía Bucofacial, Facultad de Odontología, Universidad Complutense de Madrid, Madrid, España.
authors.forename: Marta
authors.initials: M
authors.lastname: Muñoz-Corcuera
authors.affiliation: Departamento de Medicina y Cirugía Bucofacial, Facultad de Odontología, Universidad Complutense de Madrid, Madrid, España.
authors.forename: Cristina
authors.initials: C
authors.lastname: Bascones-Ilundain
mesh_terms: D059266:Bisphosphonate-Associated Osteonecrosis of the Jaw / Q000209:etiology; D004198:Disease Susceptibility; D005882:Gingival Diseases / Q000139:chemically induced; D006209:Halitosis / Q000139:chemically induced; D006474:Hemorrhagic Disorders / Q000139:chemically induced; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D009059:Mouth Diseases / Q000139:chemically induced* / Q000473:pathology; D009894:Opportunistic Infections / Q000209:etiology; D010859:Pigmentation Disorders / Q000139:chemically induced; D012466:Salivary Gland Diseases / Q000139:chemically induced; D012797:Sialometaplasia, Necrotizing / Q000139:chemically induced; D013280:Stomatitis / Q000139:chemically induced / Q000209:etiology; D013651:Taste Disorders / Q000139:chemically induced; D014060:Tongue Diseases / Q000139:chemically induced; D014662:Vasoconstrictor Agents / Q000009:adverse effects; D014987:Xerostomia / Q000139:chemically induced
chemical_list: D007166:Immunosuppressive Agents; D014662:Vasoconstrictor Agents
keywords: Adverse reaction; Cavidad bucal; Drugs; Fármacos; Oral cavity; Reacción adversa