title: Plant pleiotropic drug resistance transporters: transport mechanism, gene expression, and function.
abstract: Pleiotropic drug resistance (PDR) transporters belonging to the ABCG subfamily of ATP-binding cassette (ABC) transporters are identified only in fungi and plants. Members of this family are expressed in plants in response to various biotic and abiotic stresses and transport a diverse array of molecules across membranes. Although their detailed transport mechanism is largely unknown, they play important roles in detoxification processes, preventing water loss, transport of phytohormones, and secondary metabolites. This review provides insights into transport mechanisms of plant PDR transporters, their expression profiles, and multitude functions in plants.
authors.affiliation: Molecular Biology Research Center, School of Life Sciences, Central South University, Changsha, 410078, China.
authors.forename: Mohammed
authors.initials: M
authors.lastname: Nuruzzaman
authors.forename: Ru
authors.initials: R
authors.lastname: Zhang
authors.forename: Hong-Zhe
authors.initials: HZ
authors.lastname: Cao
authors.forename: Zhi-Yong
authors.initials: ZY
authors.lastname: Luo
mesh_terms: D018528:ATP-Binding Cassette Transporters / Q000378:metabolism*; D020869:Gene Expression Profiling; D010940:Plant Proteins / Q000378:metabolism*; D010944:Plants / Q000378:metabolism*
chemical_list: D018528:ATP-Binding Cassette Transporters; D010940:Plant Proteins
keywords: ABC transporters; expression pattern; plant defense; pleiotropic drug resistance; transport mechanism