title: Immune thrombocytopenic purpura in a liver transplant patient.
abstract: Thrombocytopenia is common during the early posttransplant period. Most cases are mild and recover in 1 month. Occasionally, severe thrombocytopenia may occur in the late posttransplant period. We report a 10-year-old boy with severe thrombocytopenia 3.5 years after liver transplant. We exclude secondary causes of thrombocytopenia. Bone marrow aspiration findings and treatment response were suggestive for immune thrombocytopenic purpura. The patient was treated with intravenous immunoglobulin at thrombocytopenia periods successfully. We continued tacrolimus, but preferred a reduced dose. In conclusion, immune thrombocytopenic purpura should be borne in mind as a reason of late onset, severe thrombocytopenia after liver transplant.
authors.affiliation: Department of Pediatric Gastroenterology, Hepatology and Nutrition, Gazi University, Ankara, Turkey.
authors.forename: Aysel
authors.initials: A
authors.lastname: Ünlüsoy Aksu
authors.forename: Ödül
authors.initials: Ö
authors.lastname: Eğritaş Gürkan
authors.forename: Sinan
authors.initials: S
authors.lastname: Sarı
authors.forename: İdil
authors.initials: İ
authors.lastname: Yenicesu
authors.forename: Buket
authors.initials: B
authors.lastname: Dalgıç
mesh_terms: D002648:Child; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D012008:Recurrence; D012720:Severity of Illness Index; D016559:Tacrolimus / Q000008:administration & dosage; D016896:Treatment Outcome
chemical_list: D016756:Immunoglobulins, Intravenous; D007166:Immunosuppressive Agents; D016559:Tacrolimus