title: All-trans retinoic acid-induced inflammatory myositis in a patient  with acute promyelocytic leukemia.
abstract: All-trans retinoic acid (ATRA), a component of standard therapy for acute promyelocytic leukemia (APL), is associated with potentially serious but treatable adverse effects involving numerous organ systems, including rare skeletal muscle involvement. Only a handful of cases of ATRA-induced myositis in children have been reported, and none in the radiology literature. We present such a case in a 15-year-old boy with APL, where recognition of imaging findings played a crucial role in making the diagnosis and facilitated prompt, effective treatment.
authors.forename: Lydia H
authors.initials: LH
authors.lastname: Pecker
authors.forename: Jason
authors.initials: J
authors.lastname: Tsai
authors.forename: Anne
authors.initials: A
authors.lastname: Angiolillo
mesh_terms: D000293:Adolescent; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003287:Contrast Media; D003907:Dexamethasone / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005682:Gadolinium; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D015473:Leukemia, Promyelocytic, Acute / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009220:Myositis / Q000139:chemically induced* / Q000175:diagnosis* / Q000188:drug therapy; D013848:Thigh / Q000473:pathology; D016896:Treatment Outcome; D014212:Tretinoin / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D003287:Contrast Media; D005938:Glucocorticoids; D014212:Tretinoin; D003907:Dexamethasone; D005682:Gadolinium