title: [Examination of relationship between lactate clearance and neurologic outcome in cardiac arrest induced by ventricular fibrillation].
abstract: A significant relationship between lactate clearance and mortality rates in cardiac arrest cases has been reported. However, the relationship between lactate clearance and neurologic outcomes in cardiac arrest cases is not clear. We examined lactate clearance in cardiac arrest cases induced by ventricular fibrillation. We investigated 13 patients with cardiac arrest induced by ventricular fibrillation from April, 2006 to March, 2012 in which therapeutic hypothermia was performed. Patients were classified into two groups: those with a favorable neurologic outcome (n=7) and those with a poor outcome (n=6). We compared lactate clearance levels between the two groups. There was no significant difference in lactate concentrations at admission and 8 or 24 hours lactate clearance between the two groups 8 or 24 hours after admission. This result suggests we may not predict the neurologic outcome of cardiac arrest cases induced by ventricular fibrillation using lactate clearance.
authors.affiliation: Division of Critical Care Medicine, Hospital of the University of Occupational and Environmental, Health, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Matsumoto
authors.forename: Shun-Ichi
authors.initials: S
authors.lastname: Nihei
authors.forename: Takeru
authors.initials: T
authors.lastname: Endo
authors.forename: Ayako
authors.initials: A
authors.lastname: Kanazawa
authors.forename: Hideaki
authors.initials: H
authors.lastname: Arai
authors.forename: Keiji
authors.initials: K
authors.lastname: Nagata
authors.forename: Yasuki
authors.initials: Y
authors.lastname: Isa
authors.forename: Motohiro
authors.initials: M
authors.lastname: Nakamura
authors.forename: Nobuya
authors.initials: N
authors.lastname: Harayama
authors.forename: Keiji
authors.initials: K
authors.lastname: Aibara
authors.forename: Masayuki
authors.initials: M
authors.lastname: Kamochi
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D005260:Female; D005544:Forecasting; D006323:Heart Arrest / Q000150:complications / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D007036:Hypothermia, Induced; D007773:Lactates / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000175:diagnosis / Q000209:etiology; D011379:Prognosis; D013997:Time Factors; D014693:Ventricular Fibrillation / Q000150:complications*
chemical_list: D015415:Biomarkers; D007773:Lactates