title: [Efficiency of safocid in the prevention of infectious and inflammatory complications after prostate biopsy].
abstract: The article is dedicated to the evaluation of the efficacy and safety of use of combined drug "Safocid" during transrectal prostate biopsy. The study included 80 patients with suspected prostate cancer who had indications for prostate biopsy. The study group (n = 40) of patients has received safocid, the control group (n = 40) of patients--pefloxacin at a dose 400 mg twice a day. Patients treated with safotsid significantly less often have reported the development of febrile hyperthermia on the 1st day after the biopsy; there was no need for changing the drug in study group compared with 6 (15%) patients in the control group. The frequency of adverse effects was not significantly different in the groups. Another positive feature of safocid is its satisfactory compliance and psychological comfort of patients used this drug. The data obtained allow to recommend the use of safocid for antibacterial prophylaxis when performing a prostate biopsy.
authors.forename: D V
authors.initials: DV
authors.lastname: Ergakov
authors.forename: A G
authors.initials: AG
authors.lastname: Martov
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001706:Biopsy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000382:microbiology / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D012189:Retrospective Studies; D014552:Urinary Tract Infections / Q000382:microbiology / Q000473:pathology / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents