title: Charcoal hemoperfusion in bupropion overdose.
abstract: Bupropion is a relatively new and popular medication for depression, with seizures as its major side effect. In the literature, there are insufficient data about hemodialysis following bupropion overdose. A 23-year-old female patient was brought to our emergency department with acute change in mental status and seizure after deliberate self-poisoning with approximately 25-30 tablets of bupropion hydrochloride. Her Glasgow coma scale score was 8/15. The patient underwent hemodialysis about 4 hours later. After 4 hours of extracorporeal treatment, she became conscious and was extubated. We present a case of full recovery after charcoal hemoperfusion following a bupropion overdose.
authors.affiliation: Department of Emergency Medicine, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey. Electronic address: hufukakdemir@hotmail.com.
authors.forename: Hızır Ufuk
authors.initials: HU
authors.lastname: Akdemir
authors.affiliation: Department of Emergency Medicine, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Calışkan
authors.affiliation: Department of Emergency Medicine, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey.
authors.forename: Latif
authors.initials: L
authors.lastname: Duran
authors.affiliation: Department of Emergency Medicine, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey.
authors.forename: Celal
authors.initials: C
authors.lastname: Katı
authors.affiliation: Department of Emergency Medicine, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey.
authors.forename: Bülent
authors.initials: B
authors.lastname: Güngörer
authors.affiliation: Department of Emergency Medicine, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey.
authors.forename: Metin
authors.initials: M
authors.lastname: Ocak
mesh_terms: D018687:Antidepressive Agents, Second-Generation / Q000506:poisoning*; D000931:Antidotes / Q000627:therapeutic use*; D016642:Bupropion / Q000506:poisoning*; D002606:Charcoal / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000188:drug therapy; D062787:Drug Overdose / Q000628:therapy*; D005260:Female; D006464:Hemoperfusion / Q000379:methods*; D006801:Humans; D055815:Young Adult
chemical_list: D018687:Antidepressive Agents, Second-Generation; D000931:Antidotes; D016642:Bupropion; D002606:Charcoal
keywords: bupropion; hemoperfusion; overdose; seizure