title: Gynecologic infections seen in ThinPrep cytological test in Wuhan, China.
abstract: This study aimed to analyze the prevalence of bacterial, Candida, Trichomonas, and human papillomavirus (HPV) infections in ThinPrep cytological test (TCT) performed on women of Wuhan, China. ThinPrep smears were screened by two independent experienced pathologists and reported from 2008 to 2010. A total of 46 866 ThinPrep smears were studied, and smears with inflammation were analyzed. Of the 44 162 enrolled patients, inflammation changes were observed in 21 935 (49.7%) and specific infections in 6884 (31.4%). The infections detected were as follows: bacteria, 5663 (82.3%); Candida, 825 (12.0%); Trichomonas, 273 (4.0%); and HPV, 148 (2.1%). Significant changes were found in the prevalence of bacteria and Candida among women who underwent TCT before and after 2010. χ(2) revealed an increasing proportion of specific infections found in smears after 2010 (P = 0.000). In conclusion, bacterial infection was the most detectable in the ThinPrep smears, followed by Candida and Trichomonas. The prevalence of infection identified by TCT was found to be similar in previous literature in China.
authors.affiliation: Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
authors.forename: Hang
authors.initials: H
authors.lastname: Zhou
authors.forename: Yao
authors.initials: Y
authors.lastname: Jia
authors.forename: Jian
authors.initials: J
authors.lastname: Shen
authors.forename: Shaoshuai
authors.initials: S
authors.lastname: Wang
authors.forename: Xiong
authors.initials: X
authors.lastname: Li
authors.forename: Ru
authors.initials: R
authors.lastname: Yang
authors.forename: Kecheng
authors.initials: K
authors.lastname: Huang
authors.forename: Ting
authors.initials: T
authors.lastname: Hu
authors.forename: Fangxu
authors.initials: F
authors.lastname: Tang
authors.forename: Jin
authors.initials: J
authors.lastname: Zhou
authors.forename: Jingping
authors.initials: J
authors.lastname: Yuan
authors.forename: Lei
authors.initials: L
authors.lastname: Huang
authors.forename: Xun
authors.initials: X
authors.lastname: Tian
authors.forename: Zhilan
authors.initials: Z
authors.lastname: Chen
authors.forename: Qinghua
authors.initials: Q
authors.lastname: Zhang
authors.forename: Changyu
authors.initials: C
authors.lastname: Wang
authors.forename: Ling
authors.initials: L
authors.lastname: Xi
authors.forename: Dongrui
authors.initials: D
authors.lastname: Deng
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Ding
authors.initials: D
authors.lastname: Ma
authors.forename: Shuang
authors.initials: S
authors.lastname: Li
mesh_terms: D000328:Adult; D000367:Age Factors; D002181:Candidiasis, Vulvovaginal / Q000453:epidemiology; D002681:China / Q000453:epidemiology; D003218:Condylomata Acuminata / Q000453:epidemiology; D005260:Female; D005831:Genital Diseases, Female / Q000453:epidemiology* / Q000382:microbiology / Q000821:virology; D006801:Humans; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D014247:Trichomonas Vaginitis / Q000453:epidemiology; D014626:Vaginal Smears