title: The emerging role of nutrition in Parkinson's disease.
abstract: Parkinson's disease (PD) is the second most prevalent neurodegenerative disease in ageing individuals. It is now clear that genetic susceptibility and environmental factors play a role in disease etiology and progression. Because environmental factors are involved with the majority of the cases of PD, it is important to understand the role nutrition plays in both neuroprotection and neurodegeneration. Recent epidemiological studies have revealed the promise of some nutrients in reducing the risk of PD. In contrast, other nutrients may be involved with the etiology of neurodegeneration or exacerbate disease progression. This review summarizes the studies that have addressed these issues and describes in detail the nutrients and their putative mechanisms of action in PD.
authors.affiliation: The Cellular and Molecular Pharmacology Department, The Chicago Medical School, Rosalind Franklin University of Medicine and Science North Chicago, IL, USA.
authors.forename: Stacey E
authors.initials: SE
authors.lastname: Seidl
authors.affiliation: The Cellular and Molecular Pharmacology Department, The Chicago Medical School, Rosalind Franklin University of Medicine and Science North Chicago, IL, USA.
authors.forename: Jose A
authors.initials: JA
authors.lastname: Santiago
authors.affiliation: The Nutrition Department, The College of Health Professions, Rosalind Franklin University of Medicine and Science North Chicago, IL, USA.
authors.forename: Hope
authors.initials: H
authors.lastname: Bilyk
authors.affiliation: The Cellular and Molecular Pharmacology Department, The Chicago Medical School, Rosalind Franklin University of Medicine and Science North Chicago, IL, USA.
authors.forename: Judith A
authors.initials: JA
authors.lastname: Potashkin
keywords: Parkinson's disease; antioxidants; neurodegeneration; neuroprotection; nutrition