title: Are EORTC risk tables suitable for Chinese patients with non-muscle-invasive bladder cancer?
abstract: OBJECTIVE
  To evaluate the applicability of using EORTC risk tables in Chinese patients with non-muscle-invasive bladder cancer.
  
  
  METHODS
  Between October 2000 and July 2009, 301 patients with NMIBC who underwent transurethral resection of the bladder tumor (TURBT) at our hospital were followed up. The probability of recurrence and progression at 1 year and 5 years post-operatively was calculated along with the 95% confidence intervals. We then compared the actual probabilities in our center to those obtained through the application of the EORTC risk tables.
  
  
  RESULTS
  Median patient age was 67 years (range, 21-92 years), and the median follow-up duration was 46 months (range, 2-151 months). The probability of recurrence at 1 year ranged from 2% to 58%, and the probability of progression ranged from less than 1.2% to 30%. At 5 years, the probability of recurrence ranged from 12% to 85%, and the probability of progression ranged from less than 2.9% to 50%. An overlapping of the confidence intervals of the probability between our series and the EORTC group is detected.
  
  
  CONCLUSIONS
  Although the immediate instillation of intravesical chemotherapy may reduce the risk of recurrence, EORTC risk tables could predict recurrence and progression in Chinese patients with non-muscle-invasive bladder cancer.
authors.affiliation: Department of Urology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Weihong
authors.initials: W
authors.lastname: Ding
authors.affiliation: Department of Pathology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Zhongqing
authors.initials: Z
authors.lastname: Chen
authors.affiliation: Department of Urology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Yuancheng
authors.initials: Y
authors.lastname: Gou
authors.affiliation: Department of Urology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Chuanyu
authors.initials: C
authors.lastname: Sun
authors.affiliation: Department of Urology, Huashan Hospital, Fudan University, Shanghai 200040, China. Electronic address: drkexu@163.com.
authors.forename: Ke
authors.initials: K
authors.lastname: Xu
authors.affiliation: Department of Biostatistics & Social Medicine, School of Public Health, Fudan University, Shanghai 200032, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Tan
authors.affiliation: Department of Urology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Shijun
authors.initials: S
authors.lastname: Tong
authors.affiliation: Department of Urology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Guowei
authors.initials: G
authors.lastname: Xia
authors.affiliation: Department of Urology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Ding
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People; D015331:Cohort Studies; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D011379:Prognosis; D018570:Risk Assessment; D001749:Urinary Bladder Neoplasms / Q000473:pathology* / Q000601:surgery; D055815:Young Adult
keywords: Non-muscle-invasive bladder cancer; Prognostic factors; Progression; Recurrence