title: Pneumonitis due to cytomegalovirus during chronic methotrexate treatment.
abstract: Although hypersensitivity pneumonitis is the most common pulmonary complication described during treatment with methotrexate, other complications like lymphoproliferative and infectious disease may be considered in the study of respiratory disease associated to methotrexate. The existence of an increased risk to developing infectious diseases may be similar to that observed during treatment with antagonists of tumor necrosis factor and corticosteroids, where Cytomegalovirus pneumonia is a serious complication; early diagnosis and treatment will prevent a potentially fatal outcome.
authors.affiliation: Servicio de Reumatología, Hospital General Universitario de Ciudad Real, Ciudad Real, España. Electronic address: hurauma@hotmail.com.
authors.forename: Marco Aurelio
authors.initials: MA
authors.lastname: Ramírez Huaranga
authors.affiliation: Servicio de Medicina Interna, Hospital General Universitario de Ciudad Real, Ciudad Real, España.
authors.forename: Erika
authors.initials: E
authors.lastname: Bencosme de Mendez
authors.affiliation: Servicio de Reumatología, Hospital General Universitario de Ciudad Real, Ciudad Real, España.
authors.forename: José Luis
authors.initials: JL
authors.lastname: Cuadra Díaz
authors.affiliation: Servicio de Neumología, Hospital General Universitario de Ciudad Real, Ciudad Real, España.
authors.forename: Javier
authors.initials: J
authors.lastname: Lázaro Polo
authors.affiliation: Servicio de Neumología, Hospital General Universitario de Ciudad Real, Ciudad Real, España.
authors.forename: Carlos
authors.initials: C
authors.lastname: Bujalance Cabrera
mesh_terms: D000369:Aged, 80 and over; D018501:Antirheumatic Agents / Q000009:adverse effects*; D003586:Cytomegalovirus Infections / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects*; D011024:Pneumonia, Viral / Q000821:virology*
chemical_list: D018501:Antirheumatic Agents; D008727:Methotrexate
keywords: Citomegalovirus; Cytomegalovirus; Methotrexate; Metotrexato; Neumonitis