title: History of distal gastrectomy prevents metabolic syndrome and chronic kidney disease.
abstract: OBJECTIVE
  Chronic kidney disease (CKD) due to metabolic syndrome has recently become a social problem in Japan. In this report, the associations between the history of distal gastrectomy (DG) and the incidence of metabolic syndrome or CKD were evaluated.
  
  
  METHODS
  Arteriosclerosis-related factors were compared among patients with a history of DG who were <70 years old (n=41) and controls selected at random (n=410) after matching for age and sex.
  
  
  RESULTS
  The patients with a history of DG were less obese than controls and had lower low-density lipoprotein cholesterol and higher high-density lipoprotein cholesterol serum levels. Furthermore, they had an excellent estimated glomerular filtration rate, which was used as an index of CKD.
  
  
  CONCLUSIONS
  These findings suggest that a history of DG prevents metabolic syndrome and reduces the risk of CKD.
authors.affiliation: Ishikawa Health Service Association, Japan. Electronic address: h-ajisaka@yobouigaku.jp.
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Ajisaka
authors.affiliation: Ishikawa Health Service Association, Japan.
authors.forename: Fumitaka
authors.initials: F
authors.lastname: Koyama
authors.affiliation: Ishikawa Health Service Association, Japan.
authors.forename: Chika
authors.initials: C
authors.lastname: Uotani
mesh_terms: D000328:Adult; D000368:Aged; D001823:Body Composition; D002784:Cholesterol / Q000097:blood; D005260:Female; D005743:Gastrectomy / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008074:Lipoproteins / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D008875:Middle Aged; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology*; D012307:Risk Factors
chemical_list: D008074:Lipoproteins; D002784:Cholesterol
keywords: Chronic kidney disease; Distal gastrectomy; High-density lipoprotein cholesterol; Low-density lipoprotein cholesterol; Metabolic syndrome