title: [The application of computer modeling in ophthalmologic investigation].
abstract: It is very difficult to measure the human eye properties directly, such as the accommodation mechanism, intraocular pressure distribution, the dynamics of aqueous humor flow and the bio-heat transfer in human eyes. Modeling and simulation may, therefore, play an increasingly important role in the ophthalmologic investigation. The major computer modeling methods, including geometric modeling, physical modeling and mathematical modeling, are introduced in this paper. Modeling and simulation anatomy properties and physiological properties of eye tissues, such as the cornea, aqueous humor and crystalline lens, vitreous, optic nerve head, sclera, are analyzed in the order from global to local, from front to back, from outside to inside. Finally, the problems of computer modeling in ophthalmologic investigation are discussed, and the development trends of the future are pointed out.
authors.forename: Min
authors.initials: M
authors.lastname: Fan
authors.forename: Peishan
authors.initials: P
authors.lastname: Dai
mesh_terms: D001082:Aqueous Humor / Q000502:physiology; D003198:Computer Simulation; D003315:Cornea / Q000502:physiology; D005123:Eye / Q000033:anatomy & histology*; D006801:Humans; D007908:Lens, Crystalline / Q000502:physiology; D009885:Ophthalmology / Q000639:trends*; D012590:Sclera / Q000502:physiology