title: Concentrations and relationships between classes of persistent halogenated organic compounds in pooled human serum samples and air from Laizhou Bay, China.
abstract: Persistent halogenated organic compounds, including polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), polybrominated diphenyl ethers (PBDEs), dechlorane plus (DP), pentabromobenzene (PBBz), and pentabromotoluene (PBT), were analyzed in pooled human serum samples from different age groups and air samples from the south coast of Laizhou Bay, Shandong Province, China. The ∑25OCP and ∑8PBDE congeners were found at higher concentrations than the other compounds, with mean concentrations of 1500 and 240ng/g lipid in serum and 330 and 140,000pg/m(3) in the air, respectively. PBBz and PBT were detected in every serum and air sample, with mean concentrations of 4.9 and 1.4ng/g lipid in serum and 100 and 250pg/m(3) in air, respectively. In serum, the mean concentrations of ∑14PCBs and ∑DP were 7.1 and 3.6ng/g lipid, respectively, and in air, the mean concentrations of ∑12dioxin-like (DL-) PCBs and ∑DP were 1.7 and 1.4pg/m(3), respectively. Different relationships were observed between the concentrations of different compounds in serum and the volunteers' ages, and the concentration distributions with age were closely related to the historic production and usage volumes of each chemical in China. The ubiquity of PCBs, OCPs, PBDEs, DP, PBBz, and PBT in serum and air is potentially concerning, and effective measures should be taken to control the concentrations of these chemicals in the environment and humans. Significant correlations were found between the chemical concentrations in serum and air, suggesting that inhalation may be an important exposure route for the residents of Laizhou Bay.
authors.affiliation: College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, PR China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Wang
authors.affiliation: College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, PR China.
authors.forename: Meng
authors.initials: M
authors.lastname: Xu
authors.affiliation: College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, PR China. Electronic address: junjin3799@126.com.
authors.forename: Jun
authors.initials: J
authors.lastname: Jin
authors.affiliation: College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, PR China.
authors.forename: Songjie
authors.initials: S
authors.lastname: He
authors.affiliation: College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, PR China.
authors.forename: Mingyuan
authors.initials: M
authors.lastname: Li
authors.affiliation: College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, PR China.
authors.forename: Yiming
authors.initials: Y
authors.lastname: Sun
mesh_terms: D000328:Adult; D061006:Bays; D002681:China; D004781:Environmental Exposure / Q000032:analysis* / Q000706:statistics & numerical data; D004785:Environmental Pollutants / Q000032:analysis / Q000097:blood*; D004787:Environmental Pollution / Q000706:statistics & numerical data; D005260:Female; D055768:Halogenated Diphenyl Ethers / Q000032:analysis / Q000097:blood; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis / Q000097:blood; D008297:Male; D011078:Polychlorinated Biphenyls / Q000032:analysis / Q000097:blood
chemical_list: D004785:Environmental Pollutants; D055768:Halogenated Diphenyl Ethers; D006843:Hydrocarbons, Chlorinated; D011078:Polychlorinated Biphenyls
keywords: Air; Correlation; Halogenated persistent organic compound; Pooled human serum sample