title: Biomimetic artificial inorganic enzyme-free self-propelled microfish robot for selective detection of Pb(2+) in water.
abstract: The availability of drinking water is of utmost importance for the world population. Anthropogenic pollutants of water, such as heavy-metal ions, are major problems in water contamination. The toxicity assays used range from cell assays to animal tests. Herein, we replace biological toxicity assays, which use higher organisms, with artificial inorganic self-propelled microtubular robots. The viability and activity of these robots are negatively influenced by heavy metals, such as Pb(2+) , in a similar manner to that of live fish models. This allows the establishment of a lethal dose (LD50 ) of heavy metal for artificial inorganic microfish robots. The self-propelled microfish robots show specific response to Pb(2+) compared to other heavy metals, such as Cd(2+) , and can be used for selective determination of Pb(2+) in water. It is a first step towards replacing the biological toxicity assays with biomimetic inorganic autonomous robotic systems.
authors.affiliation: Division of Chemistry & Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Fax: (+65) 6791-1961.
authors.forename: James Guo Sheng
authors.initials: JG
authors.lastname: Moo
authors.forename: Hong
authors.initials: H
authors.lastname: Wang
authors.forename: Guanjia
authors.initials: G
authors.lastname: Zhao
authors.forename: Martin
authors.initials: M
authors.lastname: Pumera
keywords: aquatic pollution; heavy metals; micromotors; platinum; sensors