title: Comparison of pregnancy outcome in half-dose Triptorelin and short-acting Decapeptyl in long protocol in ART cycles: A randomized clinical trial.
abstract: BACKGROUND
  Gonadotrophin-releasing hormone (GnRH) agonist is used for controlling ovarian stimulation in assisted reproductive technology (ART) cycles which has some benefits.
  
  
  OBJECTIVE
  To compare the efficacy of two different formulations of GnRH agonist: short-acting and long-acting, for ART protocols.
  
  
  METHODS
  In a prospective randomized study, one hundred women who underwent ART cycles were randomly divided into two groups. In group I, the patients received one single injection of 1.87 mg Triptorelin in previous mid-luteal phase. In group II, Decapeptyl 0.1 mg per day started from previous mid-luteal phase. Pregnancy outcome in in vitro fertilization (IVF) cycle was compared between two groups.
  
  
  RESULTS
  There were no statistically significant differences in the number of retrieved oocyte (p=0.545), fertilization (p=0.876), implantation (p=0.716) and pregnancy rate (p=0.727) between the two groups.
  
  
  CONCLUSIONS
  There were not any advantages in IVF outcome between half-dose long-acting and short-acting GnRH agonist groups in ART cycle.
authors.affiliation: Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Eftekhar
authors.affiliation: Department of Obstetrics and Gynecology, Bushehr University of Medical Sciences, Bushehr, Iran.
authors.forename: Elham
authors.initials: E
authors.lastname: Rahmani
authors.affiliation: Department of Obstetrics and Gynecology, Zanjan University of Medical Sciences, Zanjan, Iran.
authors.forename: Farnaz
authors.initials: F
authors.lastname: Mohammadian
keywords: Decapeptyl; GnRH agonist; In vitro fertilization; Infertility; Pregnancy outcome