title: Potential of tara (Caesalpinia spinosa) gallotannins and hydrolysates as natural antibacterial compounds.
abstract: Gallotannins obtained from tara pod extracts (EE) and from the products of acid hydrolysis for 4 and 9h (HE-4 and HE-9) were characterised for their composition, antioxidant activity, antimicrobial activity (AA) and minimum inhibitory concentration (MIC). Results of AA and MIC showed that EE exerted the highest inhibitory activity against Staphylococcus aureus, followed by Pseudomonas fluorescens; and among these bacteria, the antibacterial potency was enhanced after EE hydrolysis only against S. aureus. The lowest minimum inhibitory concentration (MIC) value (0.13mg gallic acid equivalent (GAE)/ml) was exerted by HE-4 against S. aureus. These results indicate that tara gallotannins have the potential to inhibit pathogenic bacteria with potential application in foods as antimicrobials and their AA can be enhanced by acid hydrolysis.
authors.affiliation: Instituto de Biotecnología (IBT), Universidad Nacional Agraria La Molina (UNALM), Av. La Molina s/n, Lima, Peru.
authors.forename: Ana
authors.initials: A
authors.lastname: Aguilar-Galvez
authors.affiliation: School of Food Science, Washington State University, FSHN Bldg., Room 106, Pullman, WA 99164, USA.
authors.forename: Giuliana
authors.initials: G
authors.lastname: Noratto
authors.affiliation: Instituto de Biotecnología (IBT), Universidad Nacional Agraria La Molina (UNALM), Av. La Molina s/n, Lima, Peru; Transfers, Interfaces and Processes (TIPs), Chemical Engineering Unit, Université Libre de Bruxelles-(ULB), 50 Avenue F.D. Roosevelt, C.P. 165/67, 1050 Brussels, Belgium.
authors.forename: Flor
authors.initials: F
authors.lastname: Chambi
authors.affiliation: Transfers, Interfaces and Processes (TIPs), Chemical Engineering Unit, Université Libre de Bruxelles-(ULB), 50 Avenue F.D. Roosevelt, C.P. 165/67, 1050 Brussels, Belgium.
authors.forename: Frédéric
authors.initials: F
authors.lastname: Debaste
authors.affiliation: Instituto de Biotecnología (IBT), Universidad Nacional Agraria La Molina (UNALM), Av. La Molina s/n, Lima, Peru. Electronic address: dcampos@lamolina.edu.pe.
authors.forename: David
authors.initials: D
authors.lastname: Campos
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D029911:Caesalpinia / Q000737:chemistry*; D047348:Hydrolyzable Tannins / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology; D013203:Staphylococcal Infections; D013211:Staphylococcus aureus / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D047348:Hydrolyzable Tannins; D010936:Plant Extracts
keywords: Gallotannins; Pseudomonas fluorescens; Staphylococcus aureus