title: Psychological and pharmacologic treatment of youth with posttraumatic stress disorder: an evidence-based review.
abstract: This article reviews the evidence for the treatment of children and adolescents with posttraumatic stress disorder (PTSD). Treatment strategies are discussed along with clinically relevant considerations with regard to choosing a modality, working with parents, and adaptations for specific populations. Current data suggest the efficacy of trauma-focused psychotherapies for the treatment of pediatric PTSD. Limited data from psychopharmacologic trials suggest that several classes of medications may have efficacy in youth with PTSD. The extant treatment studies in pediatric patients with PTSD and consensus recommendations suggest that treatment should be based on the individual child's most distressing and functionally impairing symptoms.
authors.affiliation: Department of Pediatrics, Mayerson Center for Safe and Healthy Children, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA; Division of Child and Adolescent Psychiatry, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45219, USA. Electronic address: brooks.keeshin@cchmc.org.
authors.forename: Brooks R
authors.initials: BR
authors.lastname: Keeshin
authors.affiliation: Division of Child and Adolescent Psychiatry, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45219, USA; Department of Psychiatry and Behavioral Neuroscience, College of Medicine, University of Cincinnati, 260 Stetson Street, Cincinnati, OH 45219, USA.
authors.forename: Jeffrey R
authors.initials: JR
authors.lastname: Strawn
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000927:Anticonvulsants / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D019317:Evidence-Based Medicine; D006801:Humans; D018377:Neurotransmitter Agents / Q000627:therapeutic use; D011613:Psychotherapy / Q000379:methods; D012737:Sex Factors; D013313:Stress Disorders, Post-Traumatic / Q000188:drug therapy / Q000628:therapy*; D013315:Stress, Psychological / Q000188:drug therapy / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000927:Anticonvulsants; D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D018377:Neurotransmitter Agents
keywords: Posttraumatic stress disorder; Prevention; Selective serotonin reuptake inhibitor (SSRI, SRI); Trauma; Trauma-focused cognitive behavior therapy (TF-CBT)