title: Leukemoid reaction associated with pediatric nasopharyngeal carcinoma: An unusual presentation.
abstract: Nasopharyngeal carcinoma is a tumor originating from the surface epithelial cells of nasopharynx. It is rare in children and adolescents. Most common physical finding is a neck mass. Most children with nasopharyngeal carcinoma present with advanced stage disease. The presentation with hematological abnormalities in patients without systemic metastasis is extremely rare. We reported a 14-year-old boy presenting with a mass at the right side of the pharynx and leukemoid reaction. To our knowledge, this is the first report of leukemoid reaction associated with pediatric nasopharyngeal carcinoma in English literature.
authors.affiliation: Çukurova University, Faculty of Medicine, Department of Pediatrics, Turkey.
authors.forename: Asiye Burcu
authors.initials: AB
authors.lastname: Kuş
authors.affiliation: Çukurova University, Faculty of Medicine, Department of Otorhinolaryngology, Turkey.
authors.forename: Poyraz
authors.initials: P
authors.lastname: Şahin
authors.affiliation: Çukurova University, Faculty of Medicine, Department of Pathology, Turkey.
authors.forename: Aysun Hatice
authors.initials: AH
authors.lastname: Uğuz
authors.affiliation: Çukurova University, Faculty of Medicine, Department of Pediatric Oncology/Pediatric BMT Units, Turkey.
authors.forename: Atila
authors.initials: A
authors.lastname: Tanyeli
authors.affiliation: Çukurova University, Faculty of Medicine, Department of Pediatric Oncology/Pediatric BMT Units, Turkey. Electronic address: serhankupeli@cu.edu.tr.
authors.forename: Serhan
authors.initials: S
authors.lastname: Küpeli
mesh_terms: D000293:Adolescent; D001707:Biopsy, Needle; D002277:Carcinoma; D059248:Chemoradiotherapy / Q000379:methods; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D007955:Leukemoid Reaction / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D008297:Male; D000077274:Nasopharyngeal Carcinoma; D009303:Nasopharyngeal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D035583:Rare Diseases; D016896:Treatment Outcome
keywords: Childhood; Leukemoid reaction; Nasopharyngeal carcinoma