title: Rotaxanes synthesized through sodium-ion-templated clipping of macrocycles around nonconjugated amide and urea functionalities.
abstract: A single urea or amide functionality in a dumbbell-shaped guest can be "clipped" by a macrocycle generated from a diamine and a dialdehyde through the templating effect of a Na(+) ion (see scheme). The resulting imine-containing rotaxanes can then be reduced to allow isolation of stable amine-based rotaxanes.
authors.affiliation: Department of Chemistry and Center for Emerging, Material and Advanced Devices, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei, Taiwan, 10617, (R.O.C.), Fax: (+886) 2-33661677.
authors.forename: Tsung-Hsien
authors.initials: TH
authors.lastname: Ho
authors.forename: Chien-Chen
authors.initials: CC
authors.lastname: Lai
authors.forename: Yi-Hung
authors.initials: YH
authors.lastname: Liu
authors.forename: Shie-Ming
authors.initials: SM
authors.lastname: Peng
authors.forename: Sheng-Hsien
authors.initials: SH
authors.lastname: Chiu
mesh_terms: D000577:Amides / Q000737:chemistry*; D018360:Crystallography, X-Ray; D007477:Ions / Q000737:chemistry; D047028:Macrocyclic Compounds / Q000737:chemistry; D008968:Molecular Conformation; D043862:Rotaxanes / Q000138:chemical synthesis* / Q000737:chemistry; D012964:Sodium / Q000737:chemistry*; D014508:Urea / Q000737:chemistry*
chemical_list: D000577:Amides; D007477:Ions; D047028:Macrocyclic Compounds; D043862:Rotaxanes; D014508:Urea; D012964:Sodium
keywords: amide; clipping; molecular recognition; rotaxane; template; urea