title: Epidemiological and etiological characteristics of fever, thrombocytopenia and leukopenia syndrome in Henan Province, China, 2011-2012.
abstract: The Fever, Thrombocytopenia and Leukopenia Syndrome (FTLS) is caused by a bunyavirus known as the FTLS virus (FTLSV), which was recently discovered in China. We examined the epidemiological and etiological features of 637 laboratory-confirmed cases of FTLS with onset from January 2011 to December 2012 in Henan Province, China. The highest incidence of FTLS occurred between May and August: 76.5% of all laboratory-confirmed cases occurred during those four months. Of the laboratory-confirmed cases, 60.9% were in the 46-69 years old age groups; 96.1% (612/637) occurred in farmers; 98.1% (625/637) were reported from Xinyang Prefecture. During the same time period, 2047 cases were reported in China. The nucleotide and amino acid sequences of FTLSV strains identified during 2011-2012 in Henan Province were ≥ 96% identical. This findings provides insight for developing public-health interventions for the control and prevention of FTLS in epidemic area.
authors.affiliation: Henan Center for Disease Control and Prevention, Zhengzhou, China.
authors.forename: Xueyong
authors.initials: X
authors.lastname: Huang
authors.affiliation: Henan Center for Disease Control and Prevention, Zhengzhou, China.
authors.forename: Yanhua
authors.initials: Y
authors.lastname: Du
authors.affiliation: Henan Center for Disease Control and Prevention, Zhengzhou, China; College of Public Health, Zhengzhou University, Zhengzhou, China.
authors.forename: Xiaoning
authors.initials: X
authors.lastname: Hu
authors.affiliation: Henan Center for Disease Control and Prevention, Zhengzhou, China.
authors.forename: Hongxia
authors.initials: H
authors.lastname: Ma
authors.affiliation: Henan Center for Disease Control and Prevention, Zhengzhou, China.
authors.forename: Haifeng
authors.initials: H
authors.lastname: Wang
authors.affiliation: Henan Center for Disease Control and Prevention, Zhengzhou, China.
authors.forename: Aiguo
authors.initials: A
authors.lastname: You
authors.affiliation: Henan Center for Disease Control and Prevention, Zhengzhou, China.
authors.forename: Kai
authors.initials: K
authors.lastname: Kang
authors.affiliation: Henan Center for Disease Control and Prevention, Zhengzhou, China.
authors.forename: Haomin
authors.initials: H
authors.lastname: Chen
authors.affiliation: Xinyang Center for Disease Control and Prevention, Xinyang, China.
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Henan Center for Disease Control and Prevention, Zhengzhou, China.
authors.forename: Guohua
authors.initials: G
authors.lastname: Liu
authors.affiliation: Henan Center for Disease Control and Prevention, Zhengzhou, China.
authors.forename: Bianli
authors.initials: B
authors.lastname: Xu
mesh_terms: D002681:China; D005260:Female; D005334:Fever / Q000453:epidemiology* / Q000209:etiology*; D006801:Humans; D007970:Leukopenia / Q000453:epidemiology* / Q000209:etiology*; D008297:Male; D013921:Thrombocytopenia / Q000453:epidemiology* / Q000209:etiology*