title: Screening and treatment of osteoporosis after hip fracture: comparison of sex and race.
abstract: Most patients with osteoporosis (OP) are untreated and remain so even after hip fracture. Outcomes after osteoporotic hip fractures are worse among men and non-Caucasians compared with Caucasian women. We hypothesized that screening and treatment of OP after hip fracture remains low in men and non-Caucasian women. We identified all patients aged 65 yr or older with a primary diagnosis of hip fracture (ICD9-DM code 820.xx) discharged from an urban public hospital between January 1, 2000 and December 31, 2010. Patients with active malignancy (1 yr before or after the fracture) and Paget's disease were excluded. Also, patients were excluded if they had less than 2 encounters for post-event care at the hospital. Patient charts were reviewed to obtain information on demographics, post-fracture OP screening status (dual-energy X-ray absorptiometry [DXA] ordered or resulted), OP treatment status (prescription for oral bisphosphonates, raloxifene, zoledronic acid, calcitonin, or teriparatide), and referral to rheumatology clinic. Data were captured using Research Electronic Data Capture. Differences in frequency of patients who had been evaluated by DXA and/or prescribed antiosteoporotic therapy after hip fractures overall and stratified by sex and race were evaluated using Chi-squared tests. The study was approved by our hospital institutional review board. There were a total of 596 patients discharged with a primary diagnosis of hip fracture during the study period. After exclusions, 417 patients remained and were included in the analyses. The median age was 80yr (range: 65-95), 113 (27%) were men, and 243 were White women (57.9%). Overall, 10.3% of the patients were ordered DXA after their hospital discharge, 5.4% of men and 12.1% of women (p=0.05). A total of 19% received treatment for OP, and women were nearly 3 times more likely to receive treatment than men (23.2% vs 8%, p=0.004). The rates of DXA, treatment, and referral to rheumatology did not differ by race. The frequency of OP screening using DXA scan and the initiation of OP treatment was low in all patients after fragility fractures of hip. Women were more likely than men to receive DXA and significantly more likely to receive OP treatment. Although representative of only 1 hospital, these data suggest that more attention should be paid to possible OP among elderly patients hospitalized for hip fracture, and especially among men.
authors.affiliation: Division of Rheumatology, Department of Medicine, Case Western Reserve University/MetroHealth Medical Center, Cleveland, OH, USA. Electronic address: antonelli.maria@gmail.com.
authors.forename: Maria
authors.initials: M
authors.lastname: Antonelli
authors.affiliation: Division of Rheumatology, Department of Medicine, Case Western Reserve University/MetroHealth Medical Center, Cleveland, OH, USA.
authors.forename: Douglas
authors.initials: D
authors.lastname: Einstadter
authors.affiliation: Division of Rheumatology, Department of Medicine, Case Western Reserve University/MetroHealth Medical Center, Cleveland, OH, USA.
authors.forename: Marina
authors.initials: M
authors.lastname: Magrey
mesh_terms: D015502:Absorptiometry, Photon; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D015897:Comorbidity; D057286:Electronic Health Records; D005260:Female; D006620:Hip Fractures / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000208:ethnology*; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000188:drug therapy*; D058866:Osteoporotic Fractures / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000208:ethnology*; D012737:Sex Factors
chemical_list: D050071:Bone Density Conservation Agents
keywords: Hip fracture; osteoporosis; race; screening; sex