title: Solitary fibrous tumor with rapid progression after 16 years' follow up.
abstract: A 79-year-old woman was admitted to our hospital for an investigation of a large 13-cm tumor in the chest and treatment for dyspnea in January 2010. The tumor had been observed on chest X-rays since 1992. It had measured 7 cm in 2008, then started to grow rapidly. Further investigations revealed that it was a malignant solitary fibrous tumor that was strongly suspected to have transformed from a benign to malignant state. Resection was not possible, and the patient died one month later. Benign solitary fibrous tumors of the pleura may become malignant during long-term follow-up. All suspected or proven solitary fibrous tumors of the pleura should be resected.
authors.affiliation: Division of Medical Oncology and Respiratory Medicine, Department of Internal Medicine, Shimane University Faculty of Medicine, Japan.
authors.forename: Tamio
authors.initials: T
authors.lastname: Okimoto
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Horimasu
authors.forename: Shunichi
authors.initials: S
authors.lastname: Hamaguchi
authors.forename: Akihisa
authors.initials: A
authors.lastname: Sutani
authors.forename: Chika
authors.initials: C
authors.lastname: Amano
authors.forename: Yuji
authors.initials: Y
authors.lastname: Harada
authors.forename: Riruke
authors.initials: R
authors.lastname: Maruyama
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Miyamoto
authors.forename: Koji
authors.initials: K
authors.lastname: Kishimoto
authors.forename: Takeshi
authors.initials: T
authors.lastname: Isobe
mesh_terms: D000368:Aged; D044963:Biopsy, Fine-Needle / Q000379:methods; D018450:Disease Progression; D004417:Dyspnea / Q000209:etiology; D017809:Fatal Outcome; D005221:Fatigue / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D054363:Solitary Fibrous Tumor, Pleural / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D013997:Time Factors