title: Tfh cell differentiation: missing Stat3 uncovers interferons' interference.
abstract: Viral infection induces a number of cytokines that shape T cell responses. In this issue of Immunity, Ray et al. (2014) describe how CD4(+) T cells decide on T follicular helper (Tfh) or T helper 1 (Th1) cell skewed gene expression during acute viral infection.
authors.affiliation: Institute for Immunology, Ludwig-Maximillians-University, Goethestrasse 31, 80336 Munich, Germany; Institute of Molecular Immunology, Research Unit of Molecular Immune Regulation, Helmholtz Zentrum München, Marchioninistrasse 25, 81377 Munich, Germany.
authors.forename: Stephanie L
authors.initials: SL
authors.lastname: Edelmann
authors.affiliation: Institute for Immunology, Ludwig-Maximillians-University, Goethestrasse 31, 80336 Munich, Germany; Institute of Molecular Immunology, Research Unit of Molecular Immune Regulation, Helmholtz Zentrum München, Marchioninistrasse 25, 81377 Munich, Germany. Electronic address: vigo.heissmeyer@med.uni-muenchen.de.
authors.forename: Vigo
authors.initials: V
authors.lastname: Heissmeyer
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D007370:Interferon Type I / Q000378:metabolism*; D050796:STAT3 Transcription Factor / Q000378:metabolism*; D006377:T-Lymphocytes, Helper-Inducer / Q000166:cytology* / Q000378:metabolism*
chemical_list: D007370:Interferon Type I; D050796:STAT3 Transcription Factor