title: Paravalvular regurgitation following transcutaneous aortic valve replacement: predictors and clinical significance.
abstract: Despite the higher incidence of paravalvular regurgitation (PVR) with transcatheter aortic valve replacement (TAVR), this novel treatment modality has rapidly emerged as a reasonable alternative to surgical aortic valve replacement (SAVR) in high risk and inoperable patients. This review will discuss the current literature with respect to assessment, outcomes, predictors, and intraprocedural treatment options of PVR following TAVR. Understanding the predictors may help reduce the incidence of PVR and improving the outcome of this procedure.
authors.affiliation: Columbia University Medical Center, New York-Presbyterian Hospital, 177 Fort Washington Avenue, New York, NY, 10032, USA, rth2@columbia.edu.
authors.forename: Rebecca T
authors.initials: RT
authors.lastname: Hahn
authors.forename: Susheel
authors.initials: S
authors.lastname: Kodali
authors.forename: Philippe
authors.initials: P
authors.lastname: Généreux
authors.forename: Martin
authors.initials: M
authors.lastname: Leon
mesh_terms: D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000503:physiopathology*; D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D018618:Echocardiography, Doppler, Color; D005260:Female; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D015994:Incidence; D008297:Male; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000601:surgery; D011237:Predictive Value of Tests; D012086:Reoperation; D012307:Risk Factors; D016896:Treatment Outcome