title: [Effect of occupational stress on oxidation/antioxidant capacity in nurses].
abstract: OBJECTIVE
  To investigate the effect of occupational stress on the oxidation/antioxidant capacity in nurses.
  
  
  METHODS
  A total of 131 nurses were included as study subjects. The occupational health information collection system (based on the Internet of things) was used for measurement of occupational stress. Levels of hydroxyl free radicals and antioxidant enzymes were determined.
  
  
  RESULTS
  The serum level of superoxide dismutase (SOD) was the highest in nurses under the age of 30 and the lowest in those over 45 (P < 0.05). The serum levels of glutathione peroxidase (GSH-Px) and peroxidase (POD) were the highest in nurses of working age less than 5 years, followed by those of 5-15 years, and nurses with more than 25 years' working experience showed the lowest GSH-Px and POD levels (P < 0.05). Furthermore, nurses with a university (college) degree had a higher GSH-Px level and a lower POD level compared with those with junior and senior high school degrees (P < 0.05). Job prospects and job control were positive occupational stress factors for SOD. Job hazards were negative occupational stress factors for POD. Psychological satisfaction was negative occupational stress reaction for hydroxyl free radicals. Calmness was positive occupational stress reaction for SOD, and daily stress was a negative one. The positive occupational stress reactions for GSH-Px were psychological satisfaction and job satisfaction, and daily stress was negative reaction.
  
  
  CONCLUSIONS
  Nurses with higher occupational stress have stronger oxidation and weaker antioxidant capacity, which intensifies oxidant-antioxidant imbalance and leads to oxidative stress damage.
authors.affiliation: School of Public Health, Southeast University, Nanjing, Jiangsu Province 210009, China.
authors.forename: Lili
authors.initials: L
authors.lastname: Cao
authors.affiliation: E-mail: tianhonger0@163.com.
authors.forename: Honger
authors.initials: H
authors.lastname: Tian
authors.forename: Qingdong
authors.initials: Q
authors.lastname: Zhang
authors.forename: Xinyun
authors.initials: X
authors.lastname: Zhu
authors.forename: Yongguo
authors.initials: Y
authors.lastname: Zhan
authors.forename: Jingguo
authors.initials: J
authors.lastname: Su
authors.forename: Tian
authors.initials: T
authors.lastname: Xu
authors.forename: Huabin
authors.initials: H
authors.lastname: Zhu
authors.forename: Ling
authors.initials: L
authors.lastname: Liu
mesh_terms: D000328:Adult; D005979:Glutathione Peroxidase / Q000097:blood; D006801:Humans; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D009726:Nurses / Q000523:psychology*; D018384:Oxidative Stress; D017382:Reactive Oxygen Species / Q000097:blood; D013315:Stress, Psychological / Q000097:blood*; D013482:Superoxide Dismutase / Q000097:blood; D011795:Surveys and Questionnaires
chemical_list: D017382:Reactive Oxygen Species; D008315:Malondialdehyde; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase