title: Effects of detraining after blood flow-restricted low-intensity training on muscle size and strength in older adults.
abstract: BACKGROUND
  Although blood flow-restricted low-intensity resistance training (BFR-RT) increases muscle size and strength in older adults, the effect of detraining on muscle adaptation is unclear.
  
  
  METHODS
  We investigated the effects of 24 weeks of detraining on thigh muscle cross-sectional area (CSA) and one-repetition maximum strength (1-RM) in older adults who had previously participated in 12 weeks of training (BFR-RT, 20-30 % 1-RM, knee extension and leg press) or non-BFR training.
  
  
  RESULTS
  Both 1-RM and relative dynamic strengths (1-RM divided by quadriceps femoris (QF) muscle CSA) were higher at both post-training and detraining than at pre-training for the BFR-RT group (p < 0.05). QF muscle CSA was higher at only post-training than at pre-training for the BFR-RT group (p < 0.01).
  
  
  CONCLUSIONS
  Increased muscle strength following 12 weeks of training with BFR-RT was well preserved at 24 weeks of detraining, which is due mainly to neural adaptation in older adults.
authors.affiliation: Department of Ischemic Circulatory Physiology, Graduate School of Medicine, University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan, yasuda-tomohiro@umin.ac.jp.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Yasuda
authors.forename: Kazuya
authors.initials: K
authors.lastname: Fukumura
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Sato
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Yamasoba
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Nakajima
mesh_terms: D000222:Adaptation, Physiological; D000368:Aged; D015992:Body Mass Index; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength; D018482:Muscle, Skeletal / Q000473:pathology*; D010807:Physical Endurance / Q000502:physiology; D012039:Regional Blood Flow; D055070:Resistance Training / Q000379:methods*