title: Capsules with highly active pores and interiors: versatile platforms at the nanoscale.
abstract: Spherical porous capsules offer new exciting approaches in chemistry, materials sciences, and in context of physical and biological phenomena. The underlying concepts are reported with particular emphasis on metal oxide based capsules of the {M132 } Keplerate type which display-due to their exceptional structural features and easy variation/derivatization as well as exchange of building units-an unmatched range of properties and offer unique opportunities for investigating a variety of basic aspects of nanoscience, including the discovery of some new phenomena, especially those related to hydrophobicity issues that are of significance for everyday life. This relies in particular on the existence of a large number of flexible crown ether type pores/channels and the possibility of changing the interior from completely hydrophilic to completely hydrophobic due to the presence of numerous easily exchangeable internal ligands/functionalities; the capsules can even be constructed so that they enclose a large number of highly active Lewis and Brønsted acid sites. The manifold of possible applications/uses are outlined as subtitles with reference to results as well as possible future studies. There are, among many others, options to control passing cations under different internal frames allowing also their separations, to conduct studies about hydrophobic recognitions and clustering of biological interest in water, controlled internal ion transport, nanoscale dewetting, and to carry out basic as well as new types of reactions under confined conditions.
authors.affiliation: Fakultät für Chemie, Universität Bielefeld, Postfach 100131, 33501 Bielefeld (Germany). a.mueller@uni-bielefeld.de.
authors.forename: Achim
authors.initials: A
authors.lastname: Müller
authors.forename: Pierre
authors.initials: P
authors.lastname: Gouzerh
mesh_terms: D057927:Hydrophobic and Hydrophilic Interactions; D017136:Ion Transport; D007477:Ions / Q000737:chemistry; D008024:Ligands; D008670:Metals / Q000737:chemistry*; D008832:Microchemistry; D008958:Models, Molecular; D053769:Nanocapsules / Q000737:chemistry* / Q000648:ultrastructure; D058608:Nanopores / Q000648:ultrastructure*; D010087:Oxides / Q000737:chemistry*; D010539:Permeability; D016062:Porosity; D014867:Water / Q000737:chemistry; D017155:Wettability
chemical_list: D007477:Ions; D008024:Ligands; D008670:Metals; D053769:Nanocapsules; D010087:Oxides; D014867:Water
keywords: hydrophobic effect; nanoreactors; nanoscale dewetting; polyoxometalates; semipermeability; supramolecular chemistry