title: The challenges in assessing contrast-induced nephropathy: where are we now?
abstract: OBJECTIVE
  The objective of our study was to exposit the shifting perspectives on contrast-induced nephropathy (CIN) for IV low-osmolar iodinated contrast media.
  
  
  CONCLUSIONS
  The historically inflated risk of CIN reflects logistic and intellectual pitfalls that continue to confound the study of this disease. Recent advances have clarified that the incidence of CIN is much lower than previously thought, but there are lingering questions. We suggest that CIN is likely real but is rare and offer directions for future study.
authors.affiliation: 1 Department of Radiology, University of Michigan Health System, 1500 E Medical Center Dr, B2-A209P, Ann Arbor, MI 48109-5030.
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Davenport
authors.forename: Richard H
authors.initials: RH
authors.lastname: Cohan
authors.forename: Shokoufeh
authors.initials: S
authors.lastname: Khalatbari
authors.forename: James H
authors.initials: JH
authors.lastname: Ellis
mesh_terms: D003287:Contrast Media / Q000009:adverse effects*; D003627:Data Interpretation, Statistical; D003952:Diagnostic Imaging; D006801:Humans; D007455:Iodine / Q000009:adverse effects*; D007674:Kidney Diseases / Q000139:chemically induced*; D009994:Osmolar Concentration; D061214:Patient Safety; D012307:Risk Factors
chemical_list: D003287:Contrast Media; D007455:Iodine