title: [Shift work and risk of cancer and coronary heart diseases].
abstract: Shift and night work are among the most frequent occupational exposures. Such work schedules involve exposure to light-at-night, which may reduce normal nocturnal melatonin production, create circadian rhythm disruption, sleep deprivation and unhealthy lifestyle. There is strong experimental evidence that light-at-night and circadian disruption may increase the risk of cancer and coronary heart diseases. There is emerging, but limited epidemiologic evidence that night shift work may increase breast cancer and certain cardiovascular diseases.
authors.affiliation: Center for Kræftforskning, Kræftens Bekæmpelse, Strandboulevarden 49, 2100 København Ø. johnni@cancer.dk.
authors.forename: Johnni
authors.initials: J
authors.lastname: Hansen
authors.forename: Christina Funch
authors.initials: CF
authors.lastname: Lassen
mesh_terms: D039602:After-Hours Care; D002318:Cardiovascular Diseases / Q000209:etiology*; D021081:Chronobiology Disorders / Q000150:complications; D006801:Humans; D008029:Lighting / Q000009:adverse effects; D009369:Neoplasms / Q000209:etiology*; D016273:Occupational Exposure / Q000009:adverse effects; D012307:Risk Factors; D012892:Sleep Deprivation / Q000150:complications; D014940:Work Schedule Tolerance / Q000502:physiology*