title: Pre-Descemet's endothelial keratoplasty (PDEK).
abstract: A new surgical technique for endothelial keratoplasty is described, in which the composite of pre-Descemet's layer (Dua's layer) with Descemet's membrane and endothelium is transplanted subsequent to the removal of the recipient's Descemet's membrane. The technique was performed in five eyes of five patients, with successful attachment of the graft and good postoperative visual recovery in all cases. Postoperative optical coherence tomography showed good graft attachment without interface abnormalities and a mean graft thickness was 28±5.6 μm. This study demonstrates the practicality of the technique, termed pre-Descemet's endothelial keratoplasty (PDEK), which can be a viable option in endothelial keratoplasty with some potential advantages.
authors.affiliation: Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
authors.forename: Amar
authors.initials: A
authors.lastname: Agarwal
authors.affiliation: Academic Ophthalmology, Division of Clinical Neuroscience, University of Nottingham, Nottingham, UK.
authors.forename: Harminder S
authors.initials: HS
authors.lastname: Dua
authors.affiliation: Narang Eye Care & Laser Centre, Ahmedabad, Gujarat, India.
authors.forename: Priya
authors.initials: P
authors.lastname: Narang
authors.affiliation: Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
authors.forename: Dhivya A
authors.initials: DA
authors.lastname: Kumar
authors.affiliation: Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
authors.forename: Ashvin
authors.initials: A
authors.lastname: Agarwal
authors.affiliation: Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
authors.forename: Soosan
authors.initials: S
authors.lastname: Jacob
authors.affiliation: Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
authors.forename: Athiya
authors.initials: A
authors.lastname: Agarwal
authors.affiliation: Academic Ophthalmology, Division of Clinical Neuroscience, University of Nottingham, Nottingham, UK.
authors.forename: Ankur
authors.initials: A
authors.lastname: Gupta
mesh_terms: D000368:Aged; D003316:Corneal Diseases / Q000601:surgery*; D003886:Descemet Membrane / Q000601:surgery*; D057111:Descemet Stripping Endothelial Keratoplasty / Q000379:methods*; D004728:Endothelium, Corneal / Q000637:transplantation; D005260:Female; D006085:Graft Survival; D006801:Humans; D008297:Male; D008875:Middle Aged; D020858:Tissue and Organ Harvesting / Q000379:methods; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome
keywords: Cornea; Treatment Surgery