title: Fe Doped CdTeS Magnetic Quantum Dots for Bioimaging.
abstract: A facile synthesis of 3-6 nm, water dispersible, near-infrared (NIR) emitting, quantum dots (QDs) magnetically doped with Fe is presented. Doping of alloyed CdTeS nanocrystals with Fe was achievedin situusing a simple hydrothermal method. The magnetic quantum dots (MQDs) were capped with NAcetyl-Cysteine (NAC) ligands, containing thiol and carboxylic acid functional groups to provide stable aqueous dispersion. The optical and magnetic properties of the Fe doped MQDs were characterized using several techniques. The synthesized MQDs are tuned to emit in the Vis-NIR (530-738 nm) wavelength regime and have high quantum yields (67.5-10%). NIR emitting (738 nm) MQDs having 5.6 atomic% Fe content exhibited saturation magnetization of 85 emu/gm[Fe] at room temperature. Proton transverse relaxivity of the Fe doped MQDs (738 nm) at 4.7 T was determined to be 3.6 mM-1s-1. The functional evaluation of NIR MQDs has been demonstrated using phantom andin vitrostudies. These water dispersible, NIR emitting and MR contrast producing Fe doped CdTeS MQDs, in unagglomerated form, have the potential to act as multimodal contrast agents for tracking live cells.
authors.affiliation: Particle Engineering Research Center, Materials Science and Engineering, University of Florida, Gainesville, FL 32611.
authors.forename: Ajoy K
authors.initials: AK
authors.lastname: Saha
authors.affiliation: Particle Engineering Research Center, Materials Science and Engineering, University of Florida, Gainesville, FL 32611.
authors.forename: Parvesh
authors.initials: P
authors.lastname: Sharma
authors.affiliation: Particle Engineering Research Center, Materials Science and Engineering, University of Florida, Gainesville, FL 32611.
authors.forename: Han-Byul
authors.initials: HB
authors.lastname: Sohn
authors.affiliation: Department of Physics, University of Florida, Gainesville, FL 32611.
authors.forename: Siddhartha
authors.initials: S
authors.lastname: Ghosh
authors.affiliation: Advanced Photon Source, Argonne National Lab, Argonne, Il 60439.
authors.forename: Ritesh K
authors.initials: RK
authors.lastname: Das
authors.affiliation: Department of Physics, University of Florida, Gainesville, FL 32611.
authors.forename: Arthur F
authors.initials: AF
authors.lastname: Hebard
authors.affiliation: Advanced Magnetic Resonance Imaging and Spectroscopy Facility, McKnight Brain Institute, University of Florida, National High Magnetic Field Laboratory, Gainesville, FL 32610.
authors.forename: Huadong
authors.initials: H
authors.lastname: Zeng
authors.affiliation: Physiology and Functional Genomics, University of Florida, Gainesville, FL 32611.
authors.forename: Celine
authors.initials: C
authors.lastname: Baligand
authors.affiliation: Physiology and Functional Genomics, University of Florida, Gainesville, FL 32611.
authors.forename: Glenn A
authors.initials: GA
authors.lastname: Walter
authors.affiliation: Particle Engineering Research Center, Materials Science and Engineering, University of Florida, Gainesville, FL 32611.
authors.forename: Brij M
authors.initials: BM
authors.lastname: Moudgil