title: [Pharmacological prophylaxis and treatment of recidivating respiratory disorders in children].
abstract: Interferon is the most important mediator of natural immunity, which suggests the use of interferon inducers as therapeutic and preventive agents in the treatment of acute respiratory diseases (ARDs) in children classified into a group of sickly and repeated-ARD patients. The article describes cycloferon--a drug belonging to the group of endogenous interferon inductor--and its mechanism of action, shows its prophylactic and therapeutic efficacy in children with recurrent ARDs. The clinical and pharmacological effectiveness of cycloferon has been confirmed by studying the proteomic profiles of blood plasma in sickly children.
authors.forename: M G
authors.initials: MG
authors.lastname: Romantsov
authors.forename: I M
authors.initials: IM
authors.lastname: Lysenko
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Mel'nikova
mesh_terms: D000166:Acridines / Q000627:therapeutic use*; D000208:Acute Disease; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007369:Interferon Inducers / Q000627:therapeutic use*; D008297:Male; D012008:Recurrence; D012140:Respiratory Tract Diseases / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control*
chemical_list: D000166:Acridines; D007369:Interferon Inducers; C026430:10-carboxymethyl-9-acridanone