title: Corneal crystalline deposits associated with topically applied gatifloxacin.
abstract: OBJECTIVE
  To report a case of corneal crystalline deposits from the use of gatifloxacin 0.5% topical antibiotic after combined cataract extraction and trabeculotomy ab interno surgery.
  
  
  METHODS
  A 59-year-old woman presented after combined cataract extraction and trabeculotomy ab interno with crystalline deposits in the anterior corneal stroma. Clinical examination and slit-lamp photography were performed.
  
  
  RESULTS
  The slit-lamp examination showed inferior white crystal deposition in the anterior stroma with overlying punctate epithelial erosions 4 weeks postoperatively. The eye was asymptomatic, but the deposition was cosmetically noticeable to the patient. Serial slit-lamp photography demonstrated resolution of the crystalline deposits 30 days after the discontinuation of eye drops.
  
  
  CONCLUSIONS
  The authors present a rare case of stromal crystallization from topical gatifloxacin treatment. Complete resolution of corneal deposits was seen 30 days after the discontinuation of the drops without sequelae.
authors.affiliation: Department of Ophthalmology and Visual Science, Yale Eye Center, Yale University School of Medicine, New Haven, CT.
authors.forename: Maxwell
authors.initials: M
authors.lastname: Elia
authors.forename: Sarah
authors.initials: S
authors.lastname: Khodadadeh
authors.forename: Jessica
authors.initials: J
authors.lastname: Chow
mesh_terms: D000287:Administration, Topical; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D002387:Cataract Extraction; D003316:Corneal Diseases / Q000139:chemically induced* / Q000175:diagnosis; D003319:Corneal Stroma / Q000187:drug effects* / Q000473:pathology; D003460:Crystallization; D009877:Endophthalmitis / Q000517:prevention & control; D005260:Female; D024841:Fluoroquinolones / Q000009:adverse effects*; D000077734:Gatifloxacin; D006801:Humans; D008875:Middle Aged; D009883:Ophthalmic Solutions; D014130:Trabeculectomy
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D009883:Ophthalmic Solutions; D000077734:Gatifloxacin