title: Fusion of PET and MRI for staging of uterine cervical cancer: comparison with contrast-enhanced (18)F-FDG PET/CT and pelvic MRI.
abstract: OBJECTIVE
  To investigate the fusion of pelvic magnetic resonance imaging (MRI) and fluorodeoxyglucose positron emission tomography (PET) for assessment of locoregional extension and nodal staging of cervical cancer.
  
  
  METHODS
  PET/computed tomography (CT), MRI, and non-fused and fusion of PET and MRI for assessing the extent of the primary tumor and metastasis to nodes were evaluated.
  
  
  RESULTS
  Accuracy for T-status was 83.3% for fused and non-fused PET/MRI and MRI proved significantly more accurate than PET/CT (53.3%) (P=.0077). Sensitivity, specificity, and accuracy for nodal metastasis were 92.3%, 88.2%, and 90.0% for fused PET/MRI and PET/contrast-enhanced CT; 84.6%, 94.1%, and 90.0% for non-fused PET/MRI; and 69.2%, 100%, and 86.7% for MRI.
  
  
  CONCLUSIONS
  Fused PET/MRI combines the individual advantages of MRI and PET.
authors.affiliation: Department of Radiology and of Obstetrics and Gynecology of Kobe University Graduate School of Medicine, Kobe, Japan. Electronic address: kazu10041976@yahoo.co.jp.
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Kitajima
authors.affiliation: Department of Radiology and of Obstetrics and Gynecology of Kobe University Graduate School of Medicine, Kobe, Japan.
authors.forename: Yuko
authors.initials: Y
authors.lastname: Suenaga
authors.affiliation: Department of Radiology and of Obstetrics and Gynecology of Kobe University Graduate School of Medicine, Kobe, Japan.
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Ueno
authors.affiliation: Department of Radiology, Hyogo Cancer Center, Hyogo, Japan.
authors.forename: Tomonori
authors.initials: T
authors.lastname: Kanda
authors.affiliation: Department of Radiology and of Obstetrics and Gynecology of Kobe University Graduate School of Medicine, Kobe, Japan.
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Maeda
authors.affiliation: Department of Radiology, Hyogo Cancer Center, Hyogo, Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Deguchi
authors.affiliation: Department of Radiology, Hyogo Cancer Center, Hyogo, Japan.
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Ebina
authors.affiliation: Department of Radiology, Hyogo Cancer Center, Hyogo, Japan.
authors.forename: Hideto
authors.initials: H
authors.lastname: Yamada
authors.affiliation: Department of Radiology and of Obstetrics and Gynecology of Kobe University Graduate School of Medicine, Kobe, Japan.
authors.forename: Satoru
authors.initials: S
authors.lastname: Takahashi
authors.affiliation: Department of Radiology and of Obstetrics and Gynecology of Kobe University Graduate School of Medicine, Kobe, Japan.
authors.forename: Kazuro
authors.initials: K
authors.lastname: Sugimura
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D010388:Pelvis / Q000000981:diagnostic imaging* / Q000473:pathology; D049268:Positron-Emission Tomography; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed; D002583:Uterine Cervical Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology
chemical_list: D003287:Contrast Media; D019788:Fluorodeoxyglucose F18
keywords: Fused imaging; MRI; PET/CT; Staging; Uterine cervical cancer