title: [The economic burden of prostate cancer. A systematic literature overview of registry-based studies].
abstract: BACKGROUND
  Prostate cancer, the most frequent malignant disease in males in Europe, accounts for a great proportion of health expenditures.
  
  
  OBJECTIVE
  A systematic review of registry-based studies about the cost-of-illness and related factors of prostate cancer, published in the last 10 years.
  
  
  METHODS
  A MEDLINE-based literature review was carried out between January 1, 2003 and October 1, 2013.
  
  
  RESULTS
  Fifteen peer-reviewed articles met the criteria of interest. In developed countries radiotherapy, surgical treatment and hormone therapy account for the greatest per capita costs. In Europe early stage tumours (4-7000 €, 2006), while in the USA metastatic prostate cancer (19 900-25 500 $, 2004) was associated with highest per capita expenses. In Europe the greatest costs incurred within the initial treatment (6400 €/6 months, 2008), while in the USA within the end-of-life care (depending on age: 62 200-93 400 $, 2010).
  
  
  CONCLUSIONS
  Despite public health importance of prostate cancer, the cost-of-illness literature from Europe is relatively small.
authors.affiliation: Budapesti Corvinus Egyetem Egészségügyi Közgazdaságtan Tanszék Budapest Fővám tér 8. 1093 Semmelweis Egyetem Klinikai Orvostudományok Doktori Iskola Budapest.
authors.forename: Fanni
authors.initials: F
authors.lastname: Rencz
authors.affiliation: Semmelweis Egyetem Klinikai Orvostudományok Doktori Iskola Budapest.
authors.forename: Valentin
authors.initials: V
authors.lastname: Brodszky
authors.affiliation: Országos Egészségbiztosítási Pénztár Elemzési, Orvosszakértői és Szakmai Ellenőrzési Főosztály Budapest.
authors.forename: Péter
authors.initials: P
authors.lastname: Varga
authors.affiliation: Országos Egészségbiztosítási Pénztár Budapest.
authors.forename: József
authors.initials: J
authors.lastname: Gajdácsi
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar Urológiai Klinika és Uroonkológiai Centrum Budapest.
authors.forename: Péter
authors.initials: P
authors.lastname: Nyirády
authors.affiliation: Budapesti Corvinus Egyetem Egészségügyi Közgazdaságtan Tanszék Budapest Fővám tér 8. 1093.
authors.forename: László
authors.initials: L
authors.lastname: Gulácsi
mesh_terms: D002170:Canada; D017281:Cost of Illness; D003362:Cost-Benefit Analysis; D017048:Health Care Costs; D005102:Health Expenditures; D006801:Humans; D006814:Hungary; D008297:Male; D011471:Prostatic Neoplasms / Q000191:economics*; D012042:Registries; D014481:United States
keywords: aging; betegregiszter; direct costs; economic burden; gazdasági teher; idősödés; költségek; prostatic neoplasm; prosztatarák; registries