title: Highly versatile Pd-thioether-phosphite catalytic systems for asymmetric allylic alkylation, amination, and etherification reactions.
abstract: A Pd-furanoside thioether-phosphite catalytic system that can create new C-C, C-N, and C-O bonds in several substrate types using a wide range of nucleophiles in high yields and enantioselectivities has been identified. Of particular note are the excellent enantioselectivities obtained in the etherification of linear and cyclic substrates. The potential application of the new Pd-thioether-phosphite catalytic systems was also demonstrated by the synthesis of the chiral carbo- and heterocycles.
authors.affiliation: Departament de Química Física i Inorgànica, Universitat Rovira i Virgili , C/Marcel·lí Domingo, s/n, 43007 Tarragona, Spain.
authors.forename: Mercè
authors.initials: M
authors.lastname: Coll
authors.forename: Oscar
authors.initials: O
authors.lastname: Pàmies
authors.forename: Montserrat
authors.initials: M
authors.lastname: Diéguez
mesh_terms: D000478:Alkylation; D000498:Allyl Compounds / Q000737:chemistry; D000586:Amination; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D015394:Molecular Structure; D009943:Organophosphorus Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000498:Allyl Compounds; D009943:Organophosphorus Compounds; D010165:Palladium