title: Changes observed in multiparametric prostate magnetic resonance imaging characteristics correlate with histopathological development of chronic granulomatous prostatitis after intravesical Bacillus Calmette-Guerin therapy.
abstract: Administration of Bacillus Calmette-Guerin (BCG) has been shown to cause granulomatous prostatitis, a rare inflammatory process that can be mistaken for prostate cancer. We present a case of a 78-year-old man on active surveillance for prostate cancer with a subsequent diagnosis of high-grade urothelial carcinoma. After intravesical BCG therapy, he developed chronic granulomatous prostatitis. We present serial magnetic resonance imaging and biopsy data demonstrating the time interval between BCG administration and the manifestation of chronic granulomatous prostatitis.
authors.affiliation: From the *Urologic Oncology Branch, †Laboratory of Pathology, ‡Molecular Imaging Program, and §Center for Interventional Oncology, National Cancer Institute, National Institutes of Health, Bethesda, MD.
authors.forename: Jennifer K
authors.initials: JK
authors.lastname: Logan
authors.forename: Annerleim
authors.initials: A
authors.lastname: Walton-Diaz
authors.forename: Soroush
authors.initials: S
authors.lastname: Rais-Bahrami
authors.forename: Maria J
authors.initials: MJ
authors.lastname: Merino
authors.forename: Baris
authors.initials: B
authors.lastname: Turkbey
authors.forename: Peter L
authors.initials: PL
authors.lastname: Choyke
authors.forename: Peter A
authors.initials: PA
authors.lastname: Pinto
mesh_terms: D000368:Aged; D001500:BCG Vaccine / Q000009:adverse effects*; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000175:diagnosis; D011472:Prostatitis / Q000139:chemically induced* / Q000175:diagnosis*; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000601:surgery
chemical_list: D001500:BCG Vaccine; D017430:Prostate-Specific Antigen