title: Gastric gastrointestinal stromal tumor with bone metastases - case report and review of the literature.
abstract: Gastrointestinal stromal tumors (GISTs) represent rather rare neoplasms. Most GISTs are benign; malignant tumors account for 20- 30% of cases (overall, approximately 10- 30% of GISTs exhibit malignant behavior). GISTs most commonly metastasize to the liver and abdominal cavity. Distant metastases to other sites, especially to the bones, are relatively rare. We report a case of a 62 year  old man with metastatic spread of GIST to skull, ribs and both sacroiliac joints manifesting six months after surgical resection of a gastric tumor. Although bone metastases from GISTs are rare and there are only a few reported cases in the literature, this case emphasizes that metastatic disease should always be considered in a patient with gastric GIST and suspicious bone lesions.
authors.forename: E
authors.initials: E
authors.lastname: Sahin
authors.forename: T
authors.initials: T
authors.lastname: Yetişyiğit
authors.forename: M
authors.initials: M
authors.lastname: Oznur
authors.forename: U
authors.initials: U
authors.lastname: Elboğa
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols; D001859:Bone Neoplasms / Q000556:secondary* / Q000601:surgery / Q000628:therapy; D046152:Gastrointestinal Stromal Tumors / Q000473:pathology* / Q000601:surgery / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis
chemical_list: D000970:Antineoplastic Agents