title: [Peritoneal malignant mesothelioma: review and recent data].
abstract: Peritoneal malignant mesothelioma is a rare tumor, less common than its pleural counterpart. It develops from the mesothelial cells overlying peritoneum and preferentially occurs in male, with an average age ranging from 47 to 60.5 years. Asbestos whose impact is less strong than in pleural mesothelioma, SV 40 virus, chronic peritonitis could be implicated as factors favoring the development of peritoneal mesothelioma. Clinical symptoms are not specific, and the imagery remains little or not contributive. The 2004 WHO classification recognizes 3 different types, which differ in terms of presentation and prognosis: diffuse epithelioid mesothelioma (the most common), sarcomatoid mesothelioma and biphasic mesothelioma. Many variants are described within these groups. Immunohistochemistry is mandatory to affirm or disprove peritoneal malignant mesothelioma diagnosis, based on a panel of antibodies divided in positive markers and negative markers. Indeed an accurate diagnosis is necessary to define a therapeutic strategy more and more frequently based on the combination of radical surgery and hyperthermic intra peritoneal chemotherapy. Such an approach significantly improves the prognosis of these aggressive diseases.
authors.affiliation: Département d'anatomie pathologique, institut Claudius-Regaud, 20, 24, rue du Pont-Saint-Pierre, 31052 Toulouse, France. Electronic address: mery.eliane@claudiusregaud.fr.
authors.forename: Éliane
authors.initials: É
authors.lastname: Mery
authors.affiliation: Service d'anatomie pathologique, centre hospitalier Lyon-Sud, hospices civils de Lyon, 69495 Pierre-Bénite, France.
authors.forename: Juliette
authors.initials: J
authors.lastname: Hommell-Fontaine
authors.affiliation: Département d'anatomie pathologique, centre François-Baclesse, Caen, France.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Capovilla
authors.affiliation: Service d'anatomie pathologique, CHU de l'Archet-II, Nice, France.
authors.forename: Anne
authors.initials: A
authors.lastname: Chevallier
authors.affiliation: Département d'anatomie pathologiquee, centre Val-d'Aurel, Montpellier, France.
authors.forename: Frédéric
authors.initials: F
authors.lastname: Bibeau
authors.affiliation: Département d'anatomie pathologique, insitut Bergonié, Bordeaux, France.
authors.forename: Sabrina
authors.initials: S
authors.lastname: Croce
authors.affiliation: Département d'anatomie pathologique, institut Gustave-Roussy, Villejuif, France.
authors.forename: Peggy
authors.initials: P
authors.lastname: Dartigues
authors.affiliation: Service d'anatomie pathologique, CHU de Lariboisière, Paris, France.
authors.forename: Rachid
authors.initials: R
authors.lastname: Kaci
authors.affiliation: Service d'anatomie pathologique, CHRU de Hautepierre, Strasbourg, France.
authors.forename: Gerlinde
authors.initials: G
authors.lastname: Lang-Averous
authors.affiliation: Service d'anatomie pathologique, CHU Albert-Michallon, Grenoble, France.
authors.forename: Marie-Hélène
authors.initials: MH
authors.lastname: Laverriere
authors.affiliation: Service d'anatomie pathologique, institut de cancérologie de Lorraine, Vandœuvre-lès-Nancy, France.
authors.forename: Agnès
authors.initials: A
authors.lastname: Leroux-Broussier
authors.affiliation: Service d'anatomie pathologique, CHU Jean-Minjoz, Besançon, France.
authors.forename: Flora
authors.initials: F
authors.lastname: Poizat
authors.affiliation: Département d'anatomie pathologique, centre Jean-Papin, Clermont-Ferrand, France.
authors.forename: Nina
authors.initials: N
authors.lastname: Robin
authors.affiliation: Département d'anatomie pathologique, centre Paul-Papin, Angers, France.
authors.forename: Séverine
authors.initials: S
authors.lastname: Valmary-Degano
authors.affiliation: Unité de recherche clinique, pôle information médicale, hospices civils de Lyon, Lyon, France.
authors.forename: Véronique
authors.initials: V
authors.lastname: Verriele-Beurrier
authors.affiliation: Département d'anatomie pathologique, centre Jean-Papin, Clermont-Ferrand, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Villeneuve
authors.affiliation: Département d'anatomie pathologique, institut Paoli-Calmettes, Marseille, France.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Isaac
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology; D008654:Mesothelioma / Q000473:pathology; D000086002:Mesothelioma, Malignant; D010534:Peritoneal Neoplasms / Q000473:pathology
keywords: Immunohistochemistry; Immunohistochimie; Mésothéliome malin péritonéal; Peritoneal malignant mesothelioma; Prognosis; Pronostic