title: Treatment and prevention of Mycobacterium ulcerans infection (Buruli ulcer) in Australia: guideline update.
abstract: • Guidelines reflecting contemporary clinical practice in the management of Buruli ulcer (Mycobacterium ulcerans infection) in Australia were published in 2007. • Management has continued to evolve, as new evidence has become available from randomised trials, case series and increasing clinical experience with oral antibiotic therapy. • Therefore, guidelines on the diagnosis, treatment and prevention of Buruli ulcer in Australia have been updated. They include guidance on the new role of antibiotics as first-line therapy; the shortened duration of antibiotic treatment and the use of all-oral antibiotic regimens; the continued importance, timing and role of surgery; the recognition and management of paradoxical reactions during antibiotic treatment; and updates on the prevention of disease.
authors.affiliation: Barwon Health, Geelong, VIC, Australia. danielo@barwonhealth.org.au.
authors.forename: Daniel P
authors.initials: DP
authors.lastname: O'Brien
authors.affiliation: Southern Health, Melbourne, VIC, Australia.
authors.forename: Grant
authors.initials: G
authors.lastname: Jenkin
authors.affiliation: Cornell Specialist Centre, Melbourne, VIC, Australia.
authors.forename: John
authors.initials: J
authors.lastname: Buntine
authors.affiliation: Cairns Base Hospital, Cairns, QLD, Australia.
authors.forename: Christina M
authors.initials: CM
authors.lastname: Steffen
authors.affiliation: Barwon Health, Geelong, VIC, Australia.
authors.forename: Anthony
authors.initials: A
authors.lastname: McDonald
authors.affiliation: Point Lonsdale Medical Group, Point Lonsdale, VIC, Australia.
authors.forename: Simon
authors.initials: S
authors.lastname: Horne
authors.affiliation: Barwon Health, Geelong, VIC, Australia.
authors.forename: N Deborah
authors.initials: ND
authors.lastname: Friedman
authors.affiliation: Barwon Health, Geelong, VIC, Australia.
authors.forename: Eugene
authors.initials: E
authors.lastname: Athan
authors.affiliation: Barwon Health, Geelong, VIC, Australia.
authors.forename: Andrew
authors.initials: A
authors.lastname: Hughes
authors.affiliation: St John of God Hospital, Geelong, VIC, Australia.
authors.forename: Peter P
authors.initials: PP
authors.lastname: Callan
authors.affiliation: Austin Health, Melbourne, VIC, Australia.
authors.forename: Paul D R
authors.initials: PD
authors.lastname: Johnson
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001315:Australia; D054312:Buruli Ulcer / Q000188:drug therapy* / Q000517:prevention & control / Q000601:surgery; D003646:Debridement; D004359:Drug Therapy, Combination; D006358:Hot Temperature / Q000627:therapeutic use; D006801:Humans; D019911:Mycobacterium ulcerans; D017410:Practice Guidelines as Topic; D012293:Rifampin / Q000008:administration & dosage / Q000627:therapeutic use; D013307:Streptomycin / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D012293:Rifampin; D013307:Streptomycin