title: Synthesis of sepiapterin-C via hydrolysis of 6-ethynylpteridine.
abstract: Acid hydrolysis of 6-ethynylpteridine catalyzed by mercury oxide gives 6-acetyl-2-amino-3,4-dihydropteridin-4-one in good yield. Partial reduction of the product with dissolved Al in NH3 solution afforded sepiapterin-C.
authors.forename: Winston
authors.initials: W
authors.lastname: Nxumalo
authors.forename: Andrew
authors.initials: A
authors.lastname: Dinsmore
mesh_terms: D000818:Animals; D006868:Hydrolysis; D011622:Pterins / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: C587825:6-ethynylpteridine; D011622:Pterins; C016727:sepiapterin