title: Antifungal and antibacterial activity of marine microorganisms.
abstract: In order to explore marine microorganisms with pharmaceutical potential, marine bacteria, collected from different coastal areas of the Moroccan Atlantic Ocean, were previously isolated from seawater, sediment, marine invertebrates and seaweeds. The antimicrobial activities of these microorganisms were investigated against the pathogens involved in human pathologies. Whole cultures of 34 marine microorganisms were screened for antimicrobial activities using the method of agar diffusion against three Gram-positive bacteria, two Gram-negative bacteria, and against yeast. The results showed that among the 34 isolates studied, 28 (82%) strains have antimicrobial activity against at least one pathogen studied, 11 (32%) strains have antifungal activity and 24 (76%) strains are active against Gram-positive bacteria, while 21 (62%) strains are active against Gram-negative bacteria. Among isolates having antimicrobial activity, 14 were identified and were assigned to the genera Acinetobacter, Aeromonas, Alcaligenes, Bacillus, Chromobacterium, Enterococcus, Pantoea and Pseudomonas. Due to a competitive role for space and nutrient, the marine microorganisms can produce antibiotic substance; therefore, these marine microorganisms were expected to be potential resources of natural antibiotic products.
authors.affiliation: Laboratoire de contrôle qualité en bio-industrie et molécules bioactives, faculté des sciences, université Chouaib Doukkali, BP 20, El Jadida 24000, Morocco. Electronic address: elamraouibelkassem@yahoo.fr.
authors.forename: B
authors.initials: B
authors.lastname: El Amraoui
authors.affiliation: Laboratoire de contrôle qualité en bio-industrie et molécules bioactives, faculté des sciences, université Chouaib Doukkali, BP 20, El Jadida 24000, Morocco. Electronic address: m.amraoui1@gmail.com.
authors.forename: M
authors.initials: M
authors.lastname: El Amraoui
authors.affiliation: Service de microbiologie des aliments et de l'environnement, institut Pasteur, Casablanca, Morocco. Electronic address: nozha.cohen@pasteur.ma.
authors.forename: N
authors.initials: N
authors.lastname: Cohen
authors.affiliation: Laboratoire de contrôle qualité en bio-industrie et molécules bioactives, faculté des sciences, université Chouaib Doukkali, BP 20, El Jadida 24000, Morocco. Electronic address: azizfassouane@yahoo.fr.
authors.forename: A
authors.initials: A
authors.lastname: Fassouane
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology*; D001267:Atlantic Ocean; D007448:Invertebrates / Q000382:microbiology; D012623:Seawater / Q000382:microbiology*; D012624:Seaweed / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents
keywords: Activité antimicrobienne; Antimicrobial activity; Bactéries marines; Bactéries pathogènes; Candida; Marine bacteria; Marine microorganisms; Microorganismes marins; Pathogen bacteria