title: [Non-neoplastic epithelial disorders of the vulva - lichen sclerosus].
abstract: Lichen sclerosus (LS) belongs to frequent non-neoplastic epithelial disorders of the vulva. LS is a disease of unknown ethiology, affecting mainly postmenopausal women. LS has a typical macroscopic pattern, and it is characterized with an intensive pruritus and dyspareunia. Patients with LS have a risk of scarring of external genitalia and risk of developing squamous cell carcinoma of the vulva (4-5%). Treatment of LS is usually long-term, repeated, and it is based on local potent corticosteroids. Frequent reccurences require repeated therapy. A close follow-up in a 6-months intervals and biopsy of all atypical lesions is required. Surgical treatment is rarely indicated in the management of LS. Follow-up at the specialized center is recommended.
authors.forename: M
authors.initials: M
authors.lastname: Pešek
authors.forename: J
authors.initials: J
authors.lastname: Bouda
mesh_terms: D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D014943:Global Health; D006801:Humans; D015994:Incidence; D010502:Perineum / Q000473:pathology*; D007724:Vulvar Lichen Sclerosus / Q000175:diagnosis* / Q000453:epidemiology*