title: Convenient detection of the thiol functional group using H/D isotope sensitive Raman spectroscopy.
abstract: Raman spectra of several thiols (amino acids, peptides and organic) show that the C-S-H bending mode (βCSH) shifts from ∼850 cm(-1) to ∼620 cm(-1) on deuteration of the thiol proton by simply dissolving them in D2O and CD3OD where detection by (1)H NMR is not possible. A nondestructive analytical tool for the detection of thiols in solid/neat and in solution is developed.
authors.affiliation: Department of Inorganic Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Kolkata-700032, India. icad@iacs.res.in.
authors.forename: Sabyasachi
authors.initials: S
authors.lastname: Bandyopadhyay
authors.forename: Abhishek
authors.initials: A
authors.lastname: Dey
mesh_terms: D007554:Isotopes; D013059:Spectrum Analysis, Raman / Q000379:methods*; D013438:Sulfhydryl Compounds / Q000032:analysis*
chemical_list: D007554:Isotopes; D013438:Sulfhydryl Compounds