title: Randomized controlled trial to assess the short-term effectiveness of tailored web- and text-based facilitation of smoking cessation in primary care (iQuit in practice).
abstract: OBJECTIVE
  To estimate the short-term effectiveness, feasibility and acceptability of a smoking cessation intervention (the iQuit system) that consists of tailored printed and Short Message Service (SMS) text message self-help delivered as an adjunct to cessation support in primary care to inform the design of a definitive trial.
  
  
  METHODS
  A stratified two parallel-group randomized controlled trial comparing usual care (control) with usual care plus the iQuit system (intervention), delivered by primary care nurses/healthcare assistants who were blinded to the allocation sequence.
  
  
  METHODS
  Thirty-two general practice (GP) surgeries in England, UK.
  
  
  METHODS
  A total of 602 smokers initiating smoking cessation support from their local GP surgery were randomized (control n = 303, intervention n = 299).
  
  
  METHODS
  Primary outcome was self-reported 2-week point prevalence abstinence at 8 weeks follow-up. Secondary smoking outcomes and feasibility and acceptability measures were collected at 4 weeks after quit date, 8 weeks and 6 months follow-up.
  
  
  RESULTS
  There were no significant between-group differences in the primary outcome [control 40.3%, iQuit 45.2%; odds ratio (OR) = 1.22, 95% confidence interval (CI) = 0.88-1.69] or in secondary short-term smoking outcomes. Six-month prolonged abstinence was significantly higher in the iQuit arm (control 8.9%, iQuit 15.1%; OR = 1.81, 95% CI = 1.09-3.01). iQuit support took on average 7.7 minutes (standard deviation = 4.0) to deliver and 18.9% (95% CI = 14.8-23.7%) of intervention participants discontinued the text message support during the programme.
  
  
  CONCLUSIONS
  Tailored printed and text message self-help delivered alongside routine smoking cessation support in primary care does not significantly increase short-term abstinence, but may increase long-term abstinence and demonstrated feasibility and acceptability compared with routine cessation support alone.
authors.affiliation: Behavioural Science Group, Institute of Public Health, University of Cambridge, Cambridge, UK.
authors.forename: Felix
authors.initials: F
authors.lastname: Naughton
authors.forename: James
authors.initials: J
authors.lastname: Jamison
authors.forename: Sue
authors.initials: S
authors.lastname: Boase
authors.forename: Melanie
authors.initials: M
authors.lastname: Sloan
authors.forename: Hazel
authors.initials: H
authors.lastname: Gilbert
authors.forename: A Toby
authors.initials: AT
authors.lastname: Prevost
authors.forename: Dan
authors.initials: D
authors.lastname: Mason
authors.forename: Susan
authors.initials: S
authors.lastname: Smith
authors.forename: James
authors.initials: J
authors.lastname: Brimicombe
authors.forename: Robert
authors.initials: R
authors.lastname: Evans
authors.forename: Stephen
authors.initials: S
authors.lastname: Sutton
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004739:England; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D015438:Health Behavior; D006293:Health Promotion / Q000379:methods* / Q000706:statistics & numerical data; D006801:Humans; D020407:Internet / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction / Q000706:statistics & numerical data; D016540:Smoking Cessation / Q000379:methods* / Q000706:statistics & numerical data*; D060145:Text Messaging / Q000706:statistics & numerical data*; D016896:Treatment Outcome; D055815:Young Adult
keywords: Cessation advice; computer tailoring; primary care; self-help; smoking cessation; text messaging