title: SAPS 3 is not superior to SAPS 2 in cardiac surgery patients.
abstract: OBJECTIVE
  Cardiac surgery patients are excluded from SAPS2 but included in SAPS3. Neither score is evaluated for this exclusive population; however, they are used daily. We hypothesized that SAPS3 may be superior to SAPS2 in outcome prediction in cardiac surgery patients.
  
  
  METHODS
  All consecutive patients undergoing cardiac surgery between January 2007 and December 2010 were included in our prospective study. Both models were tested with calibration and discrimination statistics. We compared the AUC of the ROC curves by DeLong's method and calculated OCC values.
  
  
  RESULTS
  A total of 5207 patients with mean age of 67.2 ± 10.9 years were admitted to the ICU. The mean length of ICU stay was 4.6 ± 7.0 days and the ICU mortality was 5.9%. The two tested models had acceptable discriminatory power (AUC: SAPS2: 0.777-0.875; SAPS3: 0.757-893). SAPS3 had a low AUC and poor calibration on admission day. SAPS2 had poor calibration on Days 1-6 and 8.
  
  
  CONCLUSIONS
  Despite including cardiac surgery patients, SAPS3 was not superior to SAPS2 in our analysis. In this large cohort of ICU cardiac surgery patients, performance of both SAPS models was generally poor. In this subset of patients, neither scoring system is recommended.
authors.forename: Fabian
authors.initials: F
authors.lastname: Doerr
authors.forename: Akmal M A
authors.initials: AM
authors.lastname: Badreldin
authors.forename: Ferzen
authors.initials: F
authors.lastname: Can
authors.forename: Ole
authors.initials: O
authors.lastname: Bayer
authors.forename: Thorsten
authors.initials: T
authors.lastname: Wahlers
authors.forename: Khosro
authors.initials: K
authors.lastname: Hekmat
mesh_terms: D000368:Aged; D006348:Cardiac Surgical Procedures; D003325:Coronary Care Units; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020379:Risk Adjustment; D012720:Severity of Illness Index