title: [Pathophysiological aspects of the diabetogenic effect of statins].
abstract: Statins are potent inhibitors of cholesterol biosynthesis. Statins are beneficial in the primary and secondary prevention of coronary heart disease. Recent studies indicate that there is an association between statin use and the development of new-onset diabetes mellitus. This article reviews the patophysiological mechanisms by different statins to explain this association.
authors.affiliation: Klintemarken 15, 2860 Søborg. pilemannlyberg@gmail.com.
authors.forename: Sascha
authors.initials: S
authors.lastname: Pilemann-Lyberg
authors.forename: Anette Bratt
authors.initials: AB
authors.lastname: Solis
authors.forename: Peter
authors.initials: P
authors.lastname: Gæde
mesh_terms: D002318:Cardiovascular Diseases / Q000188:drug therapy; D003920:Diabetes Mellitus / Q000139:chemically induced* / Q000503:physiopathology; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use; D012307:Risk Factors
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors