title: The application of histo-cytopathological biomarkers in the mud crab Scylla serrata (Forskal) to assess heavy metal toxicity in Pulicat Lake, Chennai.
abstract: The concentrations of heavy metals and their associated structural deformities in the gills, muscles and hepatopancreas of Scylla serrata from Pulicat Lake were determined and compared with crabs live along Kovalam coast. The concentrations of metals were high in the hepatopancreas and gills of crab from Pulicat Lake, whereas, low in crab from the Kovalam coast. Data were visualized using a principal component analysis (PCA). Significant differences were found for all variables at the plot scale; however, the overall variation was relatively low for muscle tissues in both stations. The structural deformities observed in the gills, hepatopancreas and muscle was due to metal toxicity, and the degree of damage was correlated with the elevated metal concentration. The results showed significant metal accumulation and histo-cytological lesions in the crabs from Pulicat Lake. The results suggest that these biomarkers are useful for assessing the impact of metal pollution in the coastal environments.
authors.affiliation: Department of Environmental Biotechnology, School of Environmental Sciences, Bharathidasan University, Tiruchirappalli 620 024, India; Unit of Aquaculture and Cryobiology, Department of Zoology, Guindy Campus, University of Madras, Chennai 600 025, India. Electronic address: arockiavasanthi@gmail.com.
authors.forename: Lourduraj
authors.initials: L
authors.lastname: Arockia Vasanthi
authors.affiliation: Unit of Aquaculture and Cryobiology, Department of Zoology, Guindy Campus, University of Madras, Chennai 600 025, India.
authors.forename: Azhagu
authors.initials: A
authors.lastname: Muruganandam
authors.affiliation: Department of Environmental Biotechnology, School of Environmental Sciences, Bharathidasan University, Tiruchirappalli 620 024, India.
authors.forename: Peranandam
authors.initials: P
authors.lastname: Revathi
authors.affiliation: Center for Bioenergy, Cooperative Research, Lincoln University, Jefferson City, MO 65101, USA.
authors.forename: Balakrishnan
authors.initials: B
authors.lastname: Baskar
authors.affiliation: Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai 600 025, India.
authors.forename: Kodhilmozhian
authors.initials: K
authors.lastname: Jayapriyan
authors.affiliation: Department of Environmental Biotechnology, School of Environmental Sciences, Bharathidasan University, Tiruchirappalli 620 024, India.
authors.forename: Ramaswamy
authors.initials: R
authors.lastname: Baburajendran
authors.affiliation: Unit of Aquaculture and Cryobiology, Department of Zoology, Guindy Campus, University of Madras, Chennai 600 025, India. Electronic address: munuswamynm@yahoo.com.
authors.forename: Natesan
authors.initials: N
authors.lastname: Munuswamy
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D003386:Brachyura / Q000187:drug effects*; D005880:Gills / Q000737:chemistry / Q000378:metabolism; D000075322:Heavy Metal Poisoning; D043143:Hepatopancreas / Q000737:chemistry / Q000378:metabolism; D007194:India; D060106:Lakes / Q000737:chemistry*; D009132:Muscles / Q000737:chemistry / Q000378:metabolism; D011041:Poisoning; D014874:Water Pollutants, Chemical / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity*
chemical_list: D015415:Biomarkers; D014874:Water Pollutants, Chemical
keywords: Biomarker; Heavy metals; Histology; Pulicat Lake; Scylla serrata; TEM