title: Detecting condylar contact loss using single-plane fluoroscopy: a comparison with in vivo force data and in vitro bi-plane data.
abstract: Knee contact mechanics play an important role in knee implant failure and wear mechanics. Femoral condylar contact loss in total knee arthroplasty has been reported in some studies and it is considered to potentially induce excessive wear of the polyethylene insert.Measuring in vivo forces applied to the tibial plateau with an instrumented prosthesis is a possible approach to assess contact loss in vivo, but this approach is not very practical. Alternatively, single-plane fluoroscopy and pose estimation can be used to derive the relative pose of the femoral component with respect to the tibial plateau and estimate the distance from the medial and lateral parts of the femoral component towards the insert. Two measures are reported in the literature: lift-off is commonly defined as the difference in distance between the medial and lateral condyles of the femoral component with respect to the tibial plateau; separation is determined by the closest distance of each condyle towards the polyethylene insert instead of the tibia plateau.In this validation study, lift-off and separation as measured with single-plane fluoroscopy are compared to in vivo contact forces measured with an instrumented knee implant. In a phantom study, lift-off and separation were compared to measurements with a high quality bi-plane measurement.The results of the in vivo contact-force experiment demonstrate a large discrepancy between single-plane fluoroscopy and the in vivo force data: single-plane fluoroscopy measured up to 5.1mm of lift-off or separation, whereas the force data never showed actual loss of contact. The phantom study demonstrated that the single-plane setup could introduce an overestimation of 0.22mm±±0.36mm. Correcting the out-of-plane position resulted in an underestimation of medial separation by -0.20mm±±0.29mm.In conclusion, there is a discrepancy between the in vivo force data and single-plane fluoroscopic measurements. Therefore contact loss may not always be determined reliably by single plane fluoroscopy analysis.
authors.affiliation: Biomechanics and Imaging Group, Department of Orthopaedics, Leiden University Medical Center, The Netherlands.
authors.forename: A H
authors.initials: AH
authors.lastname: Prins
authors.affiliation: Biomechanics and Imaging Group, Department of Orthopaedics, Leiden University Medical Center, The Netherlands. Electronic address: B.L.Kaptein@lumc.nl.
authors.forename: B L
authors.initials: BL
authors.lastname: Kaptein
authors.affiliation: Department of Mechanical & Aerospace Engineering, University of Florida, Gainesville, FL, USA.
authors.forename: S A
authors.initials: SA
authors.lastname: Banks
authors.affiliation: Division of Image Processing, Department of Radiology, Leiden University Medical Center, The Netherlands.
authors.forename: B C
authors.initials: BC
authors.lastname: Stoel
authors.affiliation: Biomechanics and Imaging Group, Department of Orthopaedics, Leiden University Medical Center, The Netherlands.
authors.forename: R G H H
authors.initials: RG
authors.lastname: Nelissen
authors.affiliation: Biomechanics and Imaging Group, Department of Orthopaedics, Leiden University Medical Center, The Netherlands; Department of Biomechanical Engineering, Faculty of Mechanical, Maritime and Materials Engineering, Delft University of Technology, The Netherlands.
authors.forename: E R
authors.initials: ER
authors.lastname: Valstar
mesh_terms: D019645:Arthroplasty, Replacement, Knee / Q000379:methods; D001696:Biomechanical Phenomena; D005269:Femur / Q000000981:diagnostic imaging / Q000502:physiology*; D005471:Fluoroscopy; D006801:Humans; D007720:Knee Prosthesis; D020959:Polyethylene; D013977:Tibia / Q000000981:diagnostic imaging / Q000502:physiology*
chemical_list: D020959:Polyethylene
keywords: Condylar lift-off; Fluoroscopic analysis; Lift-off; Pose estimation; Shape matching