title: Incidence of congenital heart disease among neonates in a neonatal unit of a tertiary care hospital.
abstract: OBJECTIVE
  To determine the incidence and pattern of various congenital heart disease in a neonatal unit of a tertiary care hospital.
  
  
  METHODS
  The prospective study was carried out in the neonatal unit of Combined Military Hospital, Rawalpindi, from September 2008 to August 2011. All 5800 neonates admitted with gestational age of > 28 weeks irrespective of birthweight were included in the study. Neonatologist/Paediatrician carried out the neonatal examination during the first 12 hours of life. Neonates suspected of having congenital heart disease were further evaluated by pulse oxymetry, X-ray chest and echocardiography to ascertain final diagnosis and type of lesion. Data was collected on a predesigned proforma containing information regarding gender, mode of delivery, gestational age, weight at birth, family history, and associated malformations. SPSS 16 was used for statistical analysis.
  
  
  RESULTS
  Of the 5800 neonates, 87 (1.5%) were found to have congenital heart disease with an incidence of 15/1000. There was a male preponderance. Most common lesion was ventricular septal defect 27 (31.3%), followed by atrial septal defect 20 (22.9%), patent ductus arteriosus 13 (14.94%), tetralogy of fallot 06 (6.89%), transposition of great arteries 04 (4.59%), Pulmonary stenosis 05 (5.79%) and 03 (3.44%) had atrioventricular canal defects.
  
  
  CONCLUSIONS
  Congenital heart disease is a common congenital anomaly. Its incidence varies from centre to centre due to different factors like nature of the sample, method of detection and early examination by a neonatologist/paediatrician. In this study a higher incidence is reported because it was carried out in a tertiary care unit, which is a referral hospital and all the neonates admitted in the unit were included in the study.
authors.forename: Shabbir
authors.initials: S
authors.lastname: Hussain
authors.forename: Moin-ud-Din
authors.initials: MU
authors.lastname: Sabir
authors.forename: Mohammad
authors.initials: M
authors.lastname: Afzal
authors.forename: Imran
authors.initials: I
authors.lastname: Asghar
mesh_terms: D004452:Echocardiography; D005260:Female; D005865:Gestational Age; D006330:Heart Defects, Congenital / Q000175:diagnosis / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal / Q000706:statistics & numerical data*; D008297:Male; D010092:Oximetry; D010154:Pakistan / Q000453:epidemiology; D011446:Prospective Studies; D013902:Radiography, Thoracic; D062606:Tertiary Care Centers / Q000706:statistics & numerical data*