title: Computing retinal contour from optical biometry.
abstract: OBJECTIVE
  To describe a new methodology that derives horizontal posterior retinal contours from partial coherence interferometry (PCI) and ray tracing using the corneal topography.
  
  
  METHODS
  Corneal topography and PCI for seven horizontal visual field eccentricities correspondent to the central 60 degrees of the posterior pole were obtained in 55 myopic eyes. A semicustomized eye model based on the subject's corneal topography and the Navarro eye model was generated using Zemax-EE software. The model was used to compute the optical path length in the seven directions where PCI measurements were obtained. Vitreous chamber depth was computed using the PCI values obtained at each of those directions. Matlab software was developed to fit the best conic curve to the set of points previously obtained. We tested the limit in the accuracy of the methodology when the actual cornea of the subject is not used and for two different lens geometries.
  
  
  RESULTS
  A standard eye model can induce an error in the retina sagitta estimation of the order of hundreds of micrometers in comparison with the semicustomized eye model. However, the use of a different lens model leads to an error of the order of tens of micrometers. The apical radius and conic constant of the average fit were -11.91 mm and -0.15, respectively. In general, a nasal-temporal asymmetry in the retina contour was found, showing mean larger values of vitreous chamber depth in the nasal side of the eye.
  
  
  CONCLUSIONS
  The use of a semicustomized eye model, together with optical path length measured by PCI for different angles, can be used to predict the retinal contour within tenths of micrometers. This methodology can be useful in studies trying to understand the effect of peripheral retinal location on myopia progression as well as modeling the optics of the human eye for a wide field.
authors.affiliation: *OD, MSc †PhD ‡OD, PhD Clinical and Experimental Optometry Research Lab (CEORLab), Center of Physics, School of Sciences (Optometry), University of Minho, Braga, Portugal (MFR, DL-F, JJ, JG-M); and CiViUM, Facultad de Óptica y Optometría, Universidad de Murcia, Murcia (NL-G); and Instituto de Ciencia de Materiales de Aragón, Consejo Superior de Investigaciones Científicas-Universidad de Zaragoza, Zaragoza (RN), Spain.
authors.forename: Miguel
authors.initials: M
authors.lastname: Faria-Ribeiro
authors.forename: Norberto
authors.initials: N
authors.lastname: López-Gil
authors.forename: Rafael
authors.initials: R
authors.lastname: Navarro
authors.forename: Daniela
authors.initials: D
authors.lastname: Lopes-Ferreira
authors.forename: Jorge
authors.initials: J
authors.lastname: Jorge
authors.forename: Jose Manuel
authors.initials: JM
authors.lastname: González-Méijome
mesh_terms: D000328:Adult; D000368:Aged; D058452:Axial Length, Eye / Q000473:pathology; D001699:Biometry / Q000379:methods; D019781:Corneal Topography / Q000379:methods*; D006801:Humans; D007368:Interferometry; D008875:Middle Aged; D008954:Models, Biological; D009216:Myopia / Q000175:diagnosis; D012160:Retina / Q000473:pathology*; D014822:Vitreous Body / Q000473:pathology; D055815:Young Adult