title: [Serological evidence of hanta virus infection (Bunyaviridae: Hantavirus) in rodents from the Sucre Department in Colombia].
abstract: OBJECTIVE
  The main goal of this research was to determine the frequency of hantavirus-specific antibodies in rodents from the municipality of San Marcos in the Sucre department of Colombia.
  
  
  METHODS
  144 rodents were captured in San Marcos' urban and rural areas using Sherman traps between December 2007 and July 2009. "Virus sin Nombre" (SNV)-specific antibodies were detected in plasma samples by an indirect ELISA immunoassay.
  
  
  RESULTS
  An 8.3 % (12/144) seroprevalence rate was found. Specific seropositivity rates ranged from 6.8 % (3/44, Zygodontomysbrevicauda) to 50 % (1/2, Neacomysspinosus). No significant differences were found in seroprevalence according to capture area, gender and/or reproductive stage (p>0.05); however, there were more seropositive adult males.
  
  
  CONCLUSIONS
  This is the first evidence of hanta virus seropositivity in rodents from the Murinae subfamily in Colombia. The presence of SNV antibodies in rodents in San Marcos supported the hypothesis that at least one hantavirusis circulating in rodents from northern Colombia.
authors.affiliation: Grupo Investigaciones Biomédicas, Universidad de Sucre.
authors.forename: Pedro
authors.initials: P
authors.lastname: Blanco
authors.affiliation: Grupo Investigaciones Biomédicas, Universidad de Sucre.
authors.forename: Stiven
authors.initials: S
authors.lastname: Arroyo
authors.affiliation: Grupo Investigaciones Biomédicas, Universidad de Sucre.
authors.forename: Homer
authors.initials: H
authors.lastname: Corrales
authors.affiliation: Grupo Investigaciones Biomédicas, Universidad de Sucre.
authors.forename: Julia
authors.initials: J
authors.lastname: Pérez
authors.affiliation: Grupo Investigaciones Biomédicas, Universidad de Sucre.
authors.forename: Lercy
authors.initials: L
authors.lastname: Álvarez
authors.affiliation: Grupo Investigaciones Biomédicas, Universidad de Sucre.
authors.forename: Anaís
authors.initials: A
authors.lastname: Castellar
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D003105:Colombia / Q000453:epidemiology; D003430:Cross-Sectional Studies; D004197:Disease Reservoirs; D005260:Female; D006476:Orthohantavirus / Q000276:immunology*; D018778:Hantavirus Infections / Q000453:epidemiology / Q000662:veterinary*; D008297:Male; D051189:Murinae / Q000821:virology; D012376:Rodent Diseases / Q000453:epidemiology* / Q000821:virology; D012377:Rodentia / Q000821:virology*; D012423:Rural Health; D016036:Seroepidemiologic Studies; D016205:Sigmodontinae / Q000821:virology; D013045:Species Specificity; D014504:Urban Health
chemical_list: D000914:Antibodies, Viral