title: The effect of normally consumed amounts of sucrose or high fructose corn syrup on lipid profiles, body composition and related parameters in overweight/obese subjects.
abstract: The American Heart Association (AHA) has advocated that women and men not consume more than 100 and 150 kcal/day, respectively, from added sugars. These levels are currently exceeded by over 90% of the adult population in the United States. Few data exist on longer-term metabolic effects when sucrose and High Fructose Corn Syrup (HFCS), the principal sources of added dietary sugars, are consumed at levels typical of the general population. Sixty five overweight and obese individuals were placed on a eucaloric (weight stable) diet for 10-weeks, which incorporated sucrose- or HFCS-sweetened, low-fat milk at 10% or 20% of calories in a randomized, double-blinded study. All groups responded similarly (interaction p > 0.05). There was no change in body weight in any of the groups over the 10-week study, or in systolic or diastolic blood pressure. Likewise, there were no changes in total cholesterol, triglycerides, low-density lipoprotein (LDL), or apolipoprotein B (Apo B). We conclude that (1) when consumed as part of a eucaloric diet fructose--when given with glucose (as normally consumed) does not promote weight gain or an atherogenic lipid profile even when consumed at two to four times the level recently recommended by the AHA. (2) There were no differences between HFCS and sucrose on these parameters.
authors.affiliation: Rippe Lifestyle Institute, 215 Celebration Place, Suite 300, Celebration, FL 34747, USA. jlowndes@rippelifestyle.com.
authors.forename: Joshua
authors.initials: J
authors.lastname: Lowndes
authors.affiliation: Rippe Lifestyle Institute, 215 Celebration Place, Suite 300, Celebration, FL 34747, USA. ssinnett@rippelifestyle.com.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Sinnett
authors.affiliation: Rippe Lifestyle Institute, 215 Celebration Place, Suite 300, Celebration, FL 34747, USA. sabrinapardo@hotmail.com.
authors.forename: Sabrina
authors.initials: S
authors.lastname: Pardo
authors.affiliation: Rippe Lifestyle Institute, 215 Celebration Place, Suite 300, Celebration, FL 34747, USA. vnguyen@rippelifestyle.com.
authors.forename: Von T
authors.initials: VT
authors.lastname: Nguyen
authors.affiliation: Energy Balance Laboratory, Department of Nutrition and Food Sciences, University of Rhode Island, Kingston, RI 02881, USA. kmelanson@uri.edu.
authors.forename: Kathleen J
authors.initials: KJ
authors.lastname: Melanson
authors.affiliation: Department of Nutrition and Dietetics, University of North Florida, 1 UNF Drive, Jacksonville, FL 32256, USA. zhiping.nutrition@gmail.com.
authors.forename: Zhiping
authors.initials: Z
authors.lastname: Yu
authors.affiliation: Britte Lowther, 4302 39th Street West, Apt # 11, Bradenton, FL 34015 , USA. Britte.lowther@gmail.com.
authors.forename: Britte E
authors.initials: BE
authors.lastname: Lowther
authors.affiliation: Rippe Lifestyle Institute, 215 Celebration Place, Suite 300, Celebration, FL 34747, USA. jrippe@rippelifestyle.com.
authors.forename: James M
authors.initials: JM
authors.lastname: Rippe
mesh_terms: D000328:Adult; D001823:Body Composition; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood*; D004032:Diet; D019422:Dietary Sucrose / Q000008:administration & dosage*; D004311:Double-Blind Method; D005260:Female; D005632:Fructose / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000378:metabolism*; D050177:Overweight / Q000378:metabolism*; D011446:Prospective Studies; D014280:Triglycerides / Q000097:blood*; D015430:Weight Gain
chemical_list: D019422:Dietary Sucrose; D014280:Triglycerides; D005632:Fructose; D002784:Cholesterol