title: Chordoid meningioma in an adult patient presenting with chronic fatigue and systemic inflammation.
abstract: We report a 27-year-old woman presenting with chronic fatigue and depressive symptoms. Aspecific neurologic symptoms and biochemical indices of inflammation and anaemia triggered an MRI, revealing a tumor with compression of the medulla oblongata. After neurosurgical resection, anatomopathologic examination showed a chordoid meningioma. All complaints disappeared and inflammatory parameters normalized, suggesting an association with Castleman syndrome. This case demonstrates the importance of a systematic diagnostic approach in patients presenting with unexplained chronic fatigue.
authors.forename: M
authors.initials: M
authors.lastname: Hamels
authors.forename: A
authors.initials: A
authors.lastname: Mariman
authors.forename: O
authors.initials: O
authors.lastname: Kalala
authors.forename: C
authors.initials: C
authors.lastname: Van den Broecke
authors.forename: L
authors.initials: L
authors.lastname: Delesie
authors.forename: E
authors.initials: E
authors.lastname: Tobback
authors.forename: D
authors.initials: D
authors.lastname: Van Roost
authors.forename: D
authors.initials: D
authors.lastname: Vogelaers
mesh_terms: D000328:Adult; D002817:Chordoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D003863:Depression / Q000209:etiology; D003937:Diagnosis, Differential; D005221:Fatigue / Q000209:etiology; D005260:Female; D006801:Humans; D007249:Inflammation / Q000209:etiology; D008579:Meningioma / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D019635:Neurosurgical Procedures; D016896:Treatment Outcome
keywords: Castleman syndrome; chordoid meningioma,; chronic fatigue,; depression,; inflammatory syndrome,