title: Incidence of hypercoagulable events after image-guided percutaneous cryoablation of renal tumors: a single-center experience.
abstract: OBJECTIVE
  To identify retrospectively hypercoagulable events that occurred over time in patients who underwent image-guided percutaneous renal cryoablation and compare the incidence with a cohort of patients who underwent surgical partial nephrectomy (PN) during the same time period.
  
  
  METHODS
  An electronic medical record database was queried for patients who underwent percutaneous image-guided renal mass cryoablation or PN between September 2006 and June 2012. Records were examined for thrombotic events during the year following the procedure in each group. Incidence rates, Kaplan-Meier estimates, and patient demographic variables were compared using the stratified log-rank test and t test for independent samples.
  
  
  RESULTS
  The study comprised 114 cryoablation cases. The cumulative incidence of thrombotic events after 1 year was 4.39%. The incidence per 100 person-years was 4.84. There were 105 PN cases. The cumulative incidence of thrombotic events after 1 year was 1.0%. The incidence per 100 person-years was 1.14. The person-time incidence rate difference for these two groups did not reach statistical significance (P = .0894).
  
  
  CONCLUSIONS
  The incidence of thrombotic events in patients who underwent percutaneous renal cryoablation in this study was not significantly different than a comparable cohort who underwent surgical PN during the same time period.
authors.affiliation: Case Western Reserve University School of Medicine, 2109 Adelbert Road, Cleveland, OH 44106. Electronic address: jason.hartman@case.edu.
authors.forename: Jason B
authors.initials: JB
authors.lastname: Hartman
authors.affiliation: Department of Radiology, University Hospitals Case Medical Center, Cleveland, OH 44106.
authors.forename: Nicholas
authors.initials: N
authors.lastname: Bhojwani
authors.affiliation: Department of Radiology, University Hospitals Case Medical Center, Cleveland, OH 44106.
authors.forename: David J
authors.initials: DJ
authors.lastname: Corn
authors.affiliation: Department of Hematology/Oncology, University Hospitals Case Medical Center, Cleveland, OH 44106.
authors.forename: Matthew M
authors.initials: MM
authors.lastname: Cooney
authors.affiliation: Department of Radiology, University Hospitals Case Medical Center, Cleveland, OH 44106.
authors.forename: John
authors.initials: J
authors.lastname: Haaga
authors.affiliation: Department of Urology, University Hospitals Case Medical Center, Cleveland, OH 44106.
authors.forename: Lee
authors.initials: L
authors.lastname: Ponsky
authors.affiliation: Department of Urology, University Hospitals Case Medical Center, Cleveland, OH 44106.
authors.forename: Robert
authors.initials: R
authors.lastname: Abouassaly
authors.affiliation: Case Western Reserve University, 2109 Adelbert Road, Cleveland, OH 44106.
authors.forename: Akshay
authors.initials: A
authors.lastname: Paspulati
authors.affiliation: The Centers for Dialysis Care, Shaker Heights, Ohio.
authors.forename: J David
authors.initials: JD
authors.lastname: Prologo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015984:Causality; D015897:Comorbidity; D003452:Cryosurgery / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D015994:Incidence; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000706:statistics & numerical data*; D009820:Ohio / Q000453:epidemiology; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D025321:Surgery, Computer-Assisted / Q000706:statistics & numerical data*; D013927:Thrombosis / Q000453:epidemiology*; D014057:Tomography, X-Ray Computed / Q000706:statistics & numerical data*; D016896:Treatment Outcome