title: Management of tardive syndromes with clozapine: a case series.
abstract: Tardive syndromes are among the most debilitating side effects associated with use of antipsychotics. In this case series we present 5 cases of drug induced tardive syndromes, who had not responded to many of the other therapeutic measures but responded to clozapine. The response rate with clozapine varied from 50% to 100% and the response was seen by week 3 in most cases. Over the long term follow-up of as long as 6 years the response to clozapine was sustained. In two cases clozapine could be stopped.
authors.affiliation: Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India. Electronic address: drsandeepg2002@gmail.com.
authors.forename: Sandeep
authors.initials: S
authors.lastname: Grover
authors.affiliation: Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
authors.forename: Nandita
authors.initials: N
authors.lastname: Hazari
authors.affiliation: Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
authors.forename: Natasha
authors.initials: N
authors.lastname: Kate
authors.affiliation: Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
authors.forename: Kaustav
authors.initials: K
authors.lastname: Chakraborty
authors.affiliation: Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
authors.forename: Akhilesh
authors.initials: A
authors.lastname: Sharma
authors.affiliation: Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
authors.forename: Dharmendra
authors.initials: D
authors.lastname: Singh
authors.affiliation: Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
authors.forename: Jyoti
authors.initials: J
authors.lastname: Gupta
authors.affiliation: Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
authors.forename: Sanjay
authors.initials: S
authors.lastname: Lahariya
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003024:Clozapine / Q000627:therapeutic use*; D004409:Dyskinesia, Drug-Induced / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011618:Psychotic Disorders / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents; D003024:Clozapine
keywords: Clozapine; Tardive dyskinesia; Tardive dystonia; Tardive syndromes