title: [A study on hepatic perfusion parameter calculation].
abstract: Hepatic perfusion parameters play an important role in detecting and diagnosing diffusion diseases of liver. Based on a hemodynamic model. In this study, we described a fast and accurate method to calculate the perfusion parameters. First, we used a dual-input one-compartment kinetics model to illustrate the distribution of the contrast agent concentration among the body. Then, we used the Gaussian function to fit the scatter concentration data of portal vein and aorta, to obtain a liver agent concentration on function of time. Finally, we solved the model parameters by using Levenberg-Marquardt algorithm, and calculated the perfusion parameters. The results showed that the method proposed in this study could calculate the parameters precisely, and had a prosperous future application possibility.
authors.forename: Fan
authors.initials: F
authors.lastname: Peng
authors.forename: Bixian
authors.initials: B
authors.lastname: Shen
authors.forename: Zhenhua
authors.initials: Z
authors.lastname: Liao
authors.forename: Weiqiang
authors.initials: W
authors.lastname: Liu
mesh_terms: D000465:Algorithms; D003287:Contrast Media; D006439:Hemodynamics; D006801:Humans; D008099:Liver / Q000502:physiology*; D008954:Models, Biological; D010477:Perfusion
chemical_list: D003287:Contrast Media