title: [Meibomian gland dysfunction: a comparative study of modern treatments].
abstract: OBJECTIVE
  To evaluate a thermal pulsation treatment compared to a warming eyelid device for the management of meibomian gland dysfunction.
  
  
  METHODS
  Thirty patients were randomized into two groups: the first had a treatment with MeiboPatch(®) on a daily basis for three months while the second had a single treatment with LipiFlow(®). The evaluation focused on a classical approach but also on a modern approach of the ocular surface (interferometry lipid layer LipiView(®)), analysis of the tear film by Oquas(®) (osmolarity by TearLab(®)) before treatment, then a month and three months later.
  
  
  RESULTS
  Both treatments proved to be effective with almost three times more functional meibomian glands at 3 months in the LipiFlow group and almost twice more in the MeiboPatch group (P<0.05) but the LipiFlow allows a more rapid improvement at the first month of treatment. Functional scores and classic exploration of the ocular surface except the Schirmer test also undergo a significant improvement in both groups after three months of treatment.
  
  
  CONCLUSIONS
  The combination of heat applied to the inner eyelid surface, together with simultaneous expression of the glands, during a single 12-minute treatment shows to be highly effective in treating cases of meibomian gland disease. Whilst results were excellent, and continued lid hygiene remains advised, the benefit of being able to simultaneous address potential compliance issues relating to ongoing treatment is significant. The convenience of a single 12-minute treatment versus an ongoing daily heating regime was shown to be highly desirable and a welcome relief in our patients' busy lifestyles.
authors.affiliation: Hôpital Morvan, CHU de Brest, 2, avenue Foch, 29609 Brest, France. Electronic address: agathebau@yahoo.fr.
authors.forename: A
authors.initials: A
authors.lastname: Baumann
authors.affiliation: Hôpital Morvan, CHU de Brest, 2, avenue Foch, 29609 Brest, France.
authors.forename: B
authors.initials: B
authors.lastname: Cochener
mesh_terms: D005141:Eyelid Diseases / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008537:Meibomian Glands; D008875:Middle Aged; D011446:Prospective Studies
keywords: Dysfonctionnement des glandes de Meibomius; Film lacrymal; Interferometry; Interférométrie; Meibomian gland dysfunction; Ocular surface; Osmolarity; Osmolarité; Surface oculaire; Tear film