title: Nutritional recovery with okara diet prevented hypercholesterolemia, hepatic steatosis and glucose intolerance.
abstract: We assessed the biological value of an okara diet and its effects on the hormonal and metabolic profile of rats submitted to protein restriction during intra-uterine life and lactation and recovered after weaning. Male rats from mothers fed either 17% or 6% protein during pregnancy and lactation were maintained on 17% casein (CC, LC), 17% okara (CO, LO) or 6% casein (LL) diets over 60 d. The nutritional quality of the okara protein was similar to that of casein. The okara diet was effective in the nutritional recovery of rats in growing that were malnourished in early life. Furthermore, the okara diet reversed the hypercholesterolemia and the hepatic steatosis observed in the malnutrition and prevented glucose intolerance in an animal model prone to diabetes mellitus.
authors.affiliation: Mestrado em Biociências, Universidade Federal de Mato Grosso , Cuiabá, MT , Brazil .
authors.forename: Simone Ferreira
authors.initials: SF
authors.lastname: Lemes
authors.forename: Faena Moura
authors.initials: FM
authors.lastname: Lima
authors.forename: Ana Paula Carli
authors.initials: AP
authors.lastname: de Almeida
authors.forename: Albina de Fátima Silva
authors.initials: Ade F
authors.lastname: Ramalho
authors.forename: Silvia Regina de Lima
authors.initials: SR
authors.lastname: Reis
authors.forename: Letícia Fonseca
authors.initials: LF
authors.lastname: Michelotto
authors.forename: Jayme
authors.initials: J
authors.lastname: Amaya-Farfán
authors.forename: Everardo Magalhães
authors.initials: EM
authors.lastname: Carneiro
authors.forename: Antonio Carlos
authors.initials: AC
authors.lastname: Boschero
authors.forename: Márcia Queiroz
authors.initials: MQ
authors.lastname: Latorraca
authors.forename: Roberto Vilela
authors.initials: RV
authors.lastname: Veloso
mesh_terms: D000818:Animals; D002364:Caseins / Q000494:pharmacology; D003920:Diabetes Mellitus / Q000209:etiology / Q000378:metabolism; D004032:Diet; D018753:Diet, Protein-Restricted; D004044:Dietary Proteins / Q000008:administration & dosage / Q000378:metabolism; D004195:Disease Models, Animal; D005234:Fatty Liver / Q000209:etiology / Q000378:metabolism / Q000517:prevention & control*; D005260:Female; D018149:Glucose Intolerance / Q000209:etiology / Q000378:metabolism / Q000517:prevention & control*; D006937:Hypercholesterolemia / Q000209:etiology / Q000378:metabolism / Q000517:prevention & control*; D008297:Male; D039382:Maternal Nutritional Physiological Phenomena; D009753:Nutritive Value; D010940:Plant Proteins / Q000494:pharmacology / Q000627:therapeutic use*; D011134:Polysaccharides / Q000494:pharmacology / Q000627:therapeutic use*; D011502:Protein-Energy Malnutrition / Q000150:complications / Q000178:diet therapy / Q000378:metabolism*; D017208:Rats, Wistar; D045730:Soy Foods; D030262:Soybean Proteins / Q000494:pharmacology / Q000627:therapeutic use; D013025:Glycine max
chemical_list: D002364:Caseins; D004044:Dietary Proteins; D010940:Plant Proteins; D011134:Polysaccharides; D030262:Soybean Proteins; C412882:okara, Glycine max
keywords: Diabetes; dietary intervention; glycaemic response; metabolic study; obesity; okara; soybean