title: Insulin-like growth factor-i and risk of differentiated thyroid carcinoma in the European prospective investigation into cancer and nutrition.
abstract: BACKGROUND
  Little is known about the causes of thyroid cancer, but insulin-like growth factor-I (IGF-I) might play an important role in its development due to its mitogenic and antiapoptotic properties.
  
  
  METHODS
  This study prospectively investigated the association between serum IGF-I concentrations and risk of differentiated thyroid carcinoma in a case-control study nested within the European Prospective Investigation into Cancer and Nutrition. The 345 incident cases of differentiated thyroid carcinoma were individually matched to 735 controls by study center, sex and age, date, time, and fasting status at blood collection, follow-up duration, and for women menopausal status, use of exogenous hormones, and phase of menstrual cycle at blood collection. Serum IGF-I concentrations were measured by immunoassay, and risk of differentiated thyroid cancer in relation to IGF-I concentration was estimated using conditional logistic regression.
  
  
  RESULTS
  There was a positive association between IGF-I concentrations and risk of differentiated thyroid carcinoma: the OR for a doubling in IGF-I concentration was 1.48 (95% confidence interval, 1.06-2.08; Ptrend = 0.02). The positive association with IGF-I was stable over time between blood collection and cancer diagnosis.
  
  
  CONCLUSIONS
  These findings suggest that IGF-I concentrations may be positively associated with risk of differentiated thyroid carcinoma.
  
  
  CONCLUSIONS
  This study provides the first prospective evidence of a potential association between circulating IGF-I concentrations and risk of differentiated thyroid carcinoma and may prompt the further investigations needed to confirm the association.
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Julie A
authors.initials: JA
authors.lastname: Schmidt
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Naomi E
authors.initials: NE
authors.lastname: Allen
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Martin
authors.initials: M
authors.lastname: Almquist
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Silvia
authors.initials: S
authors.lastname: Franceschi
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Sabina
authors.initials: S
authors.lastname: Rinaldi
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Sarah J
authors.initials: SJ
authors.lastname: Tipper
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Konstantinos K
authors.initials: KK
authors.lastname: Tsilidis
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Elisabete
authors.initials: E
authors.lastname: Weiderpass
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Kim
authors.initials: K
authors.lastname: Overvad
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Anne
authors.initials: A
authors.lastname: Tjønneland
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Boutron-Ruault
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Laure
authors.initials: L
authors.lastname: Dossus
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Sylvie
authors.initials: S
authors.lastname: Mesrine
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Rudolf
authors.initials: R
authors.lastname: Kaaks
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Annekatrin
authors.initials: A
authors.lastname: Lukanova
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Heiner
authors.initials: H
authors.lastname: Boeing
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Pagona
authors.initials: P
authors.lastname: Lagiou
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Trichopoulos
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Antonia
authors.initials: A
authors.lastname: Trichopoulou
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Domenico
authors.initials: D
authors.lastname: Palli
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Vittorio
authors.initials: V
authors.lastname: Krogh
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Salvatore
authors.initials: S
authors.lastname: Panico
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Rosario
authors.initials: R
authors.lastname: Tumino
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Roberto
authors.initials: R
authors.lastname: Zanetti
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: H Bas
authors.initials: HB
authors.lastname: Bueno-de-Mesquita
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Petra H
authors.initials: PH
authors.lastname: Peeters
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Eiliv
authors.initials: E
authors.lastname: Lund
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Virginia
authors.initials: V
authors.lastname: Menéndez
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Antonio
authors.initials: A
authors.lastname: Agudo
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: María-José
authors.initials: MJ
authors.lastname: Sánchez
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Maria-Dolores
authors.initials: MD
authors.lastname: Chirlaque
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Eva
authors.initials: E
authors.lastname: Ardanaz
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Nerea
authors.initials: N
authors.lastname: Larrañaga
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Joakim
authors.initials: J
authors.lastname: Hennings
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Maria
authors.initials: M
authors.lastname: Sandström
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Kay-Tee
authors.initials: KT
authors.lastname: Khaw
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Nick
authors.initials: N
authors.lastname: Wareham
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Isabelle
authors.initials: I
authors.lastname: Romieu
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Marc J
authors.initials: MJ
authors.lastname: Gunter
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Elio
authors.initials: E
authors.lastname: Riboli
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Key
authors.affiliation: Authors' Affiliations: Cancer Epidemiology Unit; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford; The School of Public Health; Department of Epidemiology and Biotatistics, School of Public Health, Imperial College London, London; Department of Public Health and Primary Care; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Surgery, Lund University Hospital, Lund; Malmö Diet and Cancer Study, Lund University, Malmö; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; Departments of Medical Biosciences, Pathology; Surgical and Perioperative Science; and Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; International Agency for Research on Cancer, Lyon; Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Université Paris Sud, UMRS 1018; Institut Gustave Roussy, Villejuif, France; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina; WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School; Bureau of Epidemiologic Research, Academy of Athens; Hellenic Health Foundation, Athens, Greece; Department of Community Medicine, UiT The Norwegian Arctic University, Tromsø; Department of Research, Cancer Registry of Norway, Oslo, Norway; Samfundet Folkhälsan, Helsinki, Finland; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus; Diet, Genes, and Environment, Danish Cancer Society Research Center, Copenhagen Ø, Denmark; Hormones and Cancer Group; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; Department of Epidemiology, Harvard School of Pu
authors.forename: Ruth C
authors.initials: RC
authors.lastname: Travis
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D005060:Europe; D005260:Female; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D015596:Nutrition Assessment; D011446:Prospective Studies; D012307:Risk Factors; D013964:Thyroid Neoplasms / Q000209:etiology*
chemical_list: D007334:Insulin-Like Growth Factor I