title: Determinants of depression among patients with epilepsy in Athens, Greece.
abstract: OBJECTIVE
  Depression is common among patients with epilepsy. The aim of our study was twofold: to estimate the prevalence of a major depressive episode and to identify its determinants among patients with epilepsy treated in the largest Greek hospital in Athens.
  
  
  METHODS
  All consecutive patients with epilepsy that visited the epilepsy outpatient clinic of Evangelismos General Hospital were invited to participate in the study. Ninety-four patients met our inclusion criteria.
  
  
  RESULTS
  A diagnosis of a current major depressive episode was established in 21 out of 94 eligible to participate (22.3%) patients. Being a female was associated with a 19.68-fold increase in the odds of having a major depressive episode (95% CI 3.39-114.14, p=0.001); being unemployed was associated with a 6.46-fold increase in the odds of having a major depressive episode (95% CI 1.23-34.07, p=0.028), and each extra seizure experienced per month was associated with a 1.38-fold increase in the odds of having a major depressive episode (95% CI 1.03-1.85, p=0.031).
  
  
  CONCLUSIONS
  Unemployment, female gender, and seizure control are important determinants of a major depression episode among patients with epilepsy.
authors.affiliation: Department of Neurology, Evangelismos Hospital, Athens, Greece. Electronic address: takiszis@gmail.com.
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Zis
authors.affiliation: Department of Neurology, Evangelismos Hospital, Athens, Greece.
authors.forename: Paraskevi
authors.initials: P
authors.lastname: Yfanti
authors.affiliation: Department of Neurosurgery, University of Athens, Evangelismos General Hospital, Athens, Greece.
authors.forename: Anna
authors.initials: A
authors.lastname: Siatouni
authors.affiliation: Department of Neurology, Evangelismos Hospital, Athens, Greece.
authors.forename: Antonios
authors.initials: A
authors.lastname: Tavernarakis
authors.affiliation: Department of Neurosurgery, University of Athens, Evangelismos General Hospital, Athens, Greece.
authors.forename: Stylianos
authors.initials: S
authors.lastname: Gatzonis
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D003865:Major Depressive Disorder / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology; D004827:Epilepsy / Q000150:complications*; D005260:Female; D006115:Greece / Q000453:epidemiology; D006801:Humans; D008297:Male; D015995:Prevalence
keywords: Depression; Determinants; Epilepsy; Unemployment