title: The relationship between vitamin D and obesity.
abstract: Currently, vitamin D deficiency and obesity are pandemic diseases and they are associated with cardiovascular (CV) disease, metabolic syndrome and type 2 diabetes mellitus (T2DM) and other diseases. Concentrations of 25-hydroxyvitamin D (25(OH)D) (25D) are considered as the best indicator of total body vitamin D stores. An association between reduced circulating 25D concentrations and obesity is well known, but the mechanisms are not totally clear. The role of vitamin D supplementation is still uncertain and prospective interventions will establish its influence, if any, in the treatment of obesity. Vitamin D deficiency is associated with the presence of a cardiometabolic risk profile in the obese. Future trials may establish a role for Vitamin D supplementation in individuals at increased CV risk.
authors.affiliation: Institute of nuclear sciences 'Vinca', Laboratory for Radiobiology and Molecular Genetics, University of Belgrade , Belgrade , Serbia.
authors.forename: Sanja
authors.initials: S
authors.lastname: Soskić
authors.forename: Edita
authors.initials: E
authors.lastname: Stokić
authors.forename: Esma R
authors.initials: ER
authors.lastname: Isenović
mesh_terms: D002318:Cardiovascular Diseases / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000097:blood; D006801:Humans; D024821:Metabolic Syndrome / Q000097:blood; D009765:Obesity / Q000097:blood*; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000097:blood*
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D
keywords: Cardiovascular disease; Metabolic syndrome; Obesity; Type 2 diabetes; Vitamin D