title: P-wave and QT interval dispersion analysis in children with Eisenmenger syndrome.
abstract: OBJECTIVE
  P-wave and QT dispersion are increased and associated with atrial and ventricular arrhythmia and an increase in sudden death in a variety of diseases. This study aimed to investigate P-wave and QT dispersion in children with Eisenmenger syndrome (ES).
  
  
  METHODS
  The study group included 27 children (15 females, 12 males) with both congenital heart disease (CHD) and ES. The control group consisted of 30 children with CHD without pulmonary arterial hypertension. Electrocardiographic records were used to determine P-wave, QT, and corrected QT (QTc) dispersions. 24-hour (h) rhythm Holter was fitted in all patients. Atrial volumes, ventricular dimensions and tricuspid annular plane systolic excursion (TAPSE) were measured by echocardiography.
  
  
  RESULTS
  There was no difference between groups with regard to age, sex, weight, and body surface area (p>0.05). Right atrial volume was significantly larger in the ES group than in the control group. P-wave, QT and QTc dispersions were higher in the patients with ES (50.10±11.12 vs. 26.32±8.90, p<0.001; 57.40±24.21 vs. 38.20±8.92 ms, p<0.001; and 78.20±16.02 vs. 56.52±13.92 ms, p<0.001, respectively). Ventricular and supraventricular ectopy were significantly more frequent in the ES group. Four patients (14.8%) in the study group had tachyarrhythmias during 24-h Holter monitoring.
  
  
  CONCLUSIONS
  In our study, P-wave and QT dispersion were found to be greater in children with ES than in the healthy control subjects.
authors.affiliation: Department of Pediatric Cardiology, Yüzüncü Yıl University Faculty of Medicine, Van, Turkey. dribrahimece@gmail.com.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Ece
authors.affiliation: Department of Pediatric Cardiology, Yüzüncü Yıl University Faculty of Medicine, Van, Turkey.
authors.forename: Abdurrahman
authors.initials: A
authors.lastname: Üner
authors.affiliation: Department of Pediatric Cardiology, Balıkesir Atatürk Hospital, Balıkesir, Turkey.
authors.forename: Şevket
authors.initials: Ş
authors.lastname: Ballı
authors.affiliation: Department of Pediatric Cardiology, Cumhuriyet University Faculty of Medicine, Sivas, Turkey.
authors.forename: Mehmet Burhan
authors.initials: MB
authors.lastname: Oflaz
authors.affiliation: Department of Pediatric Cardiology, Mersin Children's Hospital, Mersin, Turkey.
authors.forename: Ayşe Esin
authors.initials: AE
authors.lastname: Kibar
authors.affiliation: Department of Pediatrics, Gazi University Faculty of Medicine, Ankara, Turkey.
authors.forename: Ertan
authors.initials: E
authors.lastname: Sal
mesh_terms: D000293:Adolescent; D001145:Arrhythmias, Cardiac / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D004541:Eisenmenger Complex / Q000503:physiopathology*; D004562:Electrocardiography; D015716:Electrocardiography, Ambulatory; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D012189:Retrospective Studies