title: A volatile lactone of Hymenoscyphus pseudoalbidus, pathogen of European ash dieback, inhibits host germination.
abstract: The largely unknown secondary metabolism of the plant pathogenic fungus Hymenoscyphus pseudoalbidus was investigated by use of the CLSA method. A set of volatile lactones was identified by GC/MS. The lactones were synthesized and used in bioassays in which one of the compounds was found to be a strong germination inhibitor for ash seeds, causing necroses in the plant tissue.
authors.affiliation: Institut für Organische Chemie, Technische Universtität Braunschweig, Hagenring 30, 38106 Braunschweig (Germany).
authors.forename: Christian A
authors.initials: CA
authors.lastname: Citron
authors.forename: Corina
authors.initials: C
authors.lastname: Junker
authors.forename: Barbara
authors.initials: B
authors.lastname: Schulz
authors.forename: Jeroen S
authors.initials: JS
authors.lastname: Dickschat
mesh_terms: D001203:Ascomycota / Q000472:pathogenicity*; D031661:Fraxinus / Q000187:drug effects* / Q000382:microbiology*; D008401:Gas Chromatography-Mass Spectrometry; D018525:Germination / Q000187:drug effects*; D007783:Lactones / Q000302:isolation & purification / Q000494:pharmacology*; D010935:Plant Diseases / Q000382:microbiology*
chemical_list: D007783:Lactones
keywords: Fraxinus excelsior; Hymenoscyphus pseudoalbidus; ash dieback; lactones; plant pathogens