title: Multiple malignancies in a patient with limited granulomatosis with polyangiitis without immunosuppressive therapy.
abstract: Here, we report the case of a 69-year-old man with limited granulomatosis with polyangiitis (GPA; formerly Wegener's granulomatosis) who developed papillary thyroid cancer, adenocarcinoma of the stomach, and myelodysplastic syndrome following glucocorticoid treatment. This is the first report to present multiple malignancies in a patient with limited GPA without immunosuppressive treatment. Thus, our report supports the notion that limited GPA itself can be associated with the development of malignancy.
authors.affiliation: a Department of Internal medicine and Institute of Health Science , Gyeongsang National University School of Medicine , Jinju , South Korea.
authors.forename: Yun-Hong
authors.initials: YH
authors.lastname: Cheon
authors.affiliation: a Department of Internal medicine and Institute of Health Science , Gyeongsang National University School of Medicine , Jinju , South Korea.
authors.forename: Min-Gyo
authors.initials: MG
authors.lastname: Kim
authors.affiliation: b Department of Radiology , Gyeongsang National University School of Medicine , Jinju , South Korea.
authors.forename: Ji-Eun
authors.initials: JE
authors.lastname: Kim
authors.affiliation: a Department of Internal medicine and Institute of Health Science , Gyeongsang National University School of Medicine , Jinju , South Korea.
authors.forename: Chang Yoon
authors.initials: CY
authors.lastname: Ha
authors.affiliation: a Department of Internal medicine and Institute of Health Science , Gyeongsang National University School of Medicine , Jinju , South Korea.
authors.forename: Sang-Il
authors.initials: SI
authors.lastname: Lee
authors.affiliation: a Department of Internal medicine and Institute of Health Science , Gyeongsang National University School of Medicine , Jinju , South Korea.
authors.forename: Hyun-Ok
authors.initials: HO
authors.lastname: Kim
mesh_terms: D000230:Adenocarcinoma / Q000150:complications*; D000368:Aged; D002291:Carcinoma, Papillary / Q000150:complications*; D005938:Glucocorticoids / Q000627:therapeutic use; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008297:Male; D009190:Myelodysplastic Syndromes / Q000150:complications*; D013274:Stomach Neoplasms / Q000150:complications*; D013964:Thyroid Neoplasms / Q000150:complications*
chemical_list: D005938:Glucocorticoids
keywords: ANCA; Granulomatosis with polyangiitis; Malignancy; Myelodysplastic syndrome; Vasculitis