title: Patterns of disease distribution of lower extremity peripheral arterial disease.
abstract: Peripheral arterial disease (PAD) is a common manifestation of atherosclerosis that is associated with an increased risk of mortality and cardiovascular (CV) events. Peripheral arterial disease involves the arteries distal to the aortic bifurcation in a nonuniform manner. Studies have shown that symptoms and prognosis of patients with PAD vary according to the location and size of the affected artery. Several modalities have been used to identify the location of PAD, including noninvasive evaluations and invasive procedures. Peripheral arterial disease has a risk factor profile similar to that associated with coronary artery disease (ie, age, gender, diabetes, smoking, hypertension, and hyperlipidemia). Many studies have shown that the distribution, extent, and progression of PAD are influenced by CV risk factors but the findings are not consistent. Management strategies for PAD are different for proximal and distal PAD. The objective of this review is to discuss the patterns of diseases distribution in patients with PAD.
authors.affiliation: Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, 100853, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Chen
authors.affiliation: Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, 100853, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Shi
authors.affiliation: Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, 100853, China ytwang301@hotmail.com.
authors.forename: Yutang
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, 100853, China.
authors.forename: Xiaoying
authors.initials: X
authors.lastname: Li
mesh_terms: D001158:Arteries / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D035002:Lower Extremity / Q000098:blood supply*; D058729:Peripheral Arterial Disease / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D011237:Predictive Value of Tests; D011379:Prognosis; D018570:Risk Assessment; D012307:Risk Factors
keywords: atherosclerosis; disease distribution; lower extremity; peripheral artery disease