title: Curative effect of heat-sensitive moxibustion on chronic persistent asthma: a multicenter randomized controlled trial.
abstract: OBJECTIVE
  To compare the curative effects of heat-sensitive moxibustion with conventional drugs on chronic persistent asthma and seek a valuable therapy to replace Western Medicine.
  
  
  METHODS
  The participants in this multi-center, randomized, and controlled study were randomly divided into two groups: group A (n=144), treated with heat-sensitive moxibustion (50 sessions) and group B (n=144), treated with Seretide (salmeterol 50 plg/fluticasone 250 pg, twice a day). The scores of asthma control test (ACT), forced expiratory volume in 1 second (FEV1), peak expiratory flow (PEF), and attack frequency were measured after 15, 30, 60, and 90 days of treatment. Patients followed up 3 and 6 months after treatment.
  
  
  RESULTS
  There was a significant difference (P= 0.0002) in the ACT score and lung function between the two groups after 3 months of treatment and (P=0.000 03) during the follow-up visits. In addition, heat-sensitive moxibustion reduced attack frequency in the period from inclusion to the 6-month follow-up visit.
  
  
  CONCLUSIONS
  This study shows that heat-sensitive moxibustion may have a comparable curative effect to Seretide (salmetero/fluticasone) on asthma.
authors.forename: Rixin
authors.initials: R
authors.lastname: Chen
authors.forename: Mingren
authors.initials: M
authors.lastname: Chen
authors.forename: Jun
authors.initials: J
authors.lastname: Xiong
authors.forename: Zhenhai
authors.initials: Z
authors.lastname: Chi
authors.forename: Bo
authors.initials: B
authors.lastname: Zhang
authors.forename: Ning
authors.initials: N
authors.lastname: Tian
authors.forename: Zhenhua
authors.initials: Z
authors.lastname: Xu
authors.forename: Tangfa
authors.initials: T
authors.lastname: Zhang
authors.forename: Wanyao
authors.initials: W
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Rong
authors.forename: Zhen
authors.initials: Z
authors.lastname: Wang
authors.forename: Gang
authors.initials: G
authors.lastname: Sun
authors.forename: Baohe
authors.initials: B
authors.lastname: Ge
authors.forename: Guoxiong
authors.initials: G
authors.lastname: Yu
authors.forename: Nanchang
authors.initials: N
authors.lastname: Song
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001249:Asthma / Q000628:therapy*; D002908:Chronic Disease / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009071:Moxibustion / Q000379:methods; D016896:Treatment Outcome; D055815:Young Adult