title: Biventricular diastolic function assessed by Doppler echocardiogram in children vertically infected with human immunodeficiency virus.
abstract: OBJECTIVE
  to determine, by Doppler-echocardiography, the frequency of cardiac diastolic dysfunction in asymptomatic and clinically stable pediatric patients with vertical infection by the human immunodeficiency virus (HIV), from the cardiovascular viewpoint.
  
  
  METHODS
  this was an observational, prospective, and cross-sectional study, performed at a regional referral clinic for patients with HIV, in a convenience sample of 94 individuals, assessing biventricular diastolic function by Doppler-echocardiography, and weight, blood hemoglobin, and percentage of lymphocytes T-CD4(+).
  
  
  RESULTS
  fifty patients had diastolic dysfunction. Left ventricular dysfunction occurred in 38.7%, and the predominant type of dysfunction was decreased myocardial compliance. Right ventricular dysfunction was observed in 29.4% of the sample, and abnormal relaxation was the most prevalent type. Simultaneous biventricular dysfunction occurred in 14.1% of the individuals. There was no association between dysfunction and the immune status.
  
  
  CONCLUSIONS
  diastolic dysfunction occurred, individually or simultaneously, with no association with immune status; decreased myocardial compliance was predominant in the left ventricle, and abnormal relaxation in the right ventricle.
authors.affiliation: Hospital Infantil Joana de Gusmão, Secretaria de Estado da Saúde de Santa Catarina, Florianópolis, SC, Brazil; Hospital Universitário, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil. Electronic address: mauricio.laerte@unisul.br.
authors.forename: Mauricio L
authors.initials: ML
authors.lastname: Silva
authors.affiliation: Hospital Universitário, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil; Department of Informatics and Statistics, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
authors.forename: Silvia M
authors.initials: SM
authors.lastname: Nassar
authors.affiliation: Hospital Universitário, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
authors.forename: André P
authors.initials: AP
authors.lastname: Silva
authors.affiliation: Hospital Infantil Joana de Gusmão, Secretaria de Estado da Saúde de Santa Catarina, Florianópolis, SC, Brazil.
authors.forename: Leandro L
authors.initials: LL
authors.lastname: Ponce
authors.affiliation: Hospital Infantil Joana de Gusmão, Secretaria de Estado da Saúde de Santa Catarina, Florianópolis, SC, Brazil; Hospital Universitário, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
authors.forename: Maria M de S
authors.initials: MM
authors.lastname: Pires
mesh_terms: D000293:Adolescent; D001938:Brazil; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D015150:Echocardiography, Doppler; D005260:Female; D015658:HIV Infections / Q000503:physiopathology / Q000635:transmission*; D006801:Humans; D007223:Infant; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D008943:Mitral Valve / Q000000981:diagnostic imaging; D010044:Outpatient Clinics, Hospital; D011446:Prospective Studies; D014261:Tricuspid Valve / Q000000981:diagnostic imaging; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000503:physiopathology; D016276:Ventricular Function / Q000502:physiology*
keywords: Children; Crianças; Doenças infecciosas; Função ventricular; Infectious diseases; Ventricular function