title: Massive exudative retinal detachment following photodynamic therapy for retinal hemangioma in von Hippel-Lindau Syndrome.
abstract: Photodynamic therapy (PDT) is a common treatment on retinal capillary hemangioma. We applied PDT to a patient with von Hippel-Lindau(VHL) syndrome and she developed severe massive exudative retinal detachment the next day, which is a rare complication for PDT. After intraocular anti-VEGF agent and peribulbar dexamethasone several times to the patient, her subretinal fluid disappeared and hemangiomas atrophied. Treatment with Anti-VEGF agent and corticosteroid is effective for such complication.
authors.affiliation: Department of Ophthalmology, the 2nd Xiangya Hospital, Central South University, Changsha, PR China.
authors.forename: Yao
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Department of Ophthalmology, the 2nd Xiangya Hospital, Central South University, Changsha, PR China.
authors.forename: Hong
authors.initials: H
authors.lastname: Liu
authors.affiliation: Department of Ophthalmology, the 2nd Xiangya Hospital, Central South University, Changsha, PR China.
authors.forename: Kun
authors.initials: K
authors.lastname: Zhang
authors.affiliation: Department of Ophthalmology, the 2nd Xiangya Hospital, Central South University, Changsha, PR China. Electronic address: gaoling66@hotmail.com.
authors.forename: Ling
authors.initials: L
authors.lastname: Gao
mesh_terms: D000328:Adult; D005260:Female; D018324:Hemangioma, Capillary / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D010778:Photochemotherapy / Q000009:adverse effects*; D017319:Photosensitizing Agents / Q000009:adverse effects / Q000627:therapeutic use; D011166:Porphyrins / Q000009:adverse effects* / Q000627:therapeutic use*; D012163:Retinal Detachment / Q000139:chemically induced* / Q000517:prevention & control / Q000628:therapy*; D016896:Treatment Outcome; D000077362:Verteporfin; D006623:von Hippel-Lindau Disease / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D017319:Photosensitizing Agents; D011166:Porphyrins; D000077362:Verteporfin
keywords: Photodynamic therapy; Retinal detachment; Retinal hemangioma