title: A cluster of endophthalmitis caused by Mycobacterium abscessus after cataract surgery.
abstract: We report two cases of postoperative endophthalmitis after cataract surgery caused by the same strain of Mycobacterium abscessus confirmed by arbitrarily primed polymerase chain reaction, sequencing of the erythromycin ribosome methyltransferase gene and pulsed-field gel electrophoresis. The outcomes were poor despite aggressive treatments. This is the first report of nontuberculous mycobacteria as a causative pathogen for a cluster of endophthalmitis.
authors.affiliation: Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
authors.forename: Jia-Horung
authors.initials: JH
authors.lastname: Hung
authors.affiliation: Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
authors.forename: Yi-Hsun
authors.initials: YH
authors.lastname: Huang
authors.affiliation: Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
authors.forename: Tsung-Chain
authors.initials: TC
authors.lastname: Chang
authors.affiliation: Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
authors.forename: Sung-Huei
authors.initials: SH
authors.lastname: Tseng
authors.affiliation: Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
authors.forename: Min-Hsiu
authors.initials: MH
authors.lastname: Shih
authors.affiliation: Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
authors.forename: Jiunn-Jong
authors.initials: JJ
authors.lastname: Wu
authors.affiliation: Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address: HFCnckuhoph@gmail.com.
authors.forename: Fu-Chin
authors.initials: FC
authors.lastname: Huang
mesh_terms: D000293:Adolescent; D000368:Aged; D000583:Amikacin / Q000627:therapeutic use; D001623:Betamethasone / Q000627:therapeutic use; D002386:Cataract / Q000382:microbiology*; D016521:Electrophoresis, Gel, Pulsed-Field / Q000379:methods; D009877:Endophthalmitis / Q000382:microbiology* / Q000473:pathology; D005123:Eye / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008780:Methyltransferases / Q000235:genetics; D008875:Middle Aged; D058889:Molecular Typing; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy / Q000382:microbiology*; D009170:Nontuberculous Mycobacteria / Q000145:classification* / Q000302:isolation & purification*; D013508:Ophthalmologic Surgical Procedures / Q000009:adverse effects*; D016133:Polymerase Chain Reaction; D011183:Postoperative Complications / Q000188:drug therapy / Q000382:microbiology; D013624:Taiwan; D014821:Vitrectomy
chemical_list: D000583:Amikacin; D001623:Betamethasone; D008780:Methyltransferases; C019613:S-adenosylmethionine-erythromycin O-methyltransferase
keywords: Atypical mycobacteria; Endophthalmitis; Mycobacterium abscessus infection; Nontuberculous mycobacteria