title: [Recurrent respiratory diseases in children].
abstract: The review deals with recurrent respiratory diseases in children. The concept of frequently ill children is characterized and the properties of the pathogens are described. The factors promoting development of recurrent respiratory diseases, including hereditary predisposition (mother health condition) are indicated and the genetic determination of the recurrent diseases associated with the blood group is shown. Development of immune dysbalance evident of changes in the cellular humoral immune response and in the factors of nonspecific resistance, that characterize changes in the local immunity in such children leading to chronic pathologic processes, is concerned. The effect of the atopic conditions and allergic diseases on the severity of respiratory pathology is stated. Interaction and mechanisms of development of neuroendocrine and immune systems are described. Cycloferon is shown to be useful in correction of impaired immune resistance in frequently ill children that promotes less frequent episodes and shorter terms of recurrent acute respiratory diseases per year.
authors.forename: I M
authors.initials: IM
authors.lastname: Lysenko
authors.forename: M G
authors.initials: MG
authors.lastname: Romantsov
mesh_terms: D000166:Acridines / Q000627:therapeutic use; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012008:Recurrence; D012140:Respiratory Tract Diseases / Q000453:epidemiology / Q000235:genetics / Q000276:immunology / Q000517:prevention & control; D012720:Severity of Illness Index
chemical_list: D000166:Acridines; C026430:10-carboxymethyl-9-acridanone