title: A preliminary investigation of serological tools for the detection of Onchocerca lupi infection in dogs.
abstract: Onchocerca lupi is a neglected filarioid causing nodular lesions associated with acute or chronic ocular disease in dogs. Despite the recent appraisal of its zoonotic potential, human cases are increasingly reported in the Old and New Worlds. Therefore, the development of accurate tools for the rapid diagnosis of O. lupi infections in dogs is becoming a priority. In this study, we conducted a preliminary investigation aimed at evaluating the usefulness of a commercially available ELISA test for the detection of O. lupi antigens in canine sera. The potential use of this tool for larger epidemiological studies of canine onchocerciasis is discussed.
authors.affiliation: Dipartimento di Medicina Veterinaria, Università degli Studi di Bari, 70010 , Valenzano, Bari, Italy.
authors.forename: Alessio
authors.initials: A
authors.lastname: Giannelli
authors.forename: Cinzia
authors.initials: C
authors.lastname: Cantacessi
authors.forename: Patricia
authors.initials: P
authors.lastname: Graves
authors.forename: Luke
authors.initials: L
authors.lastname: Becker
authors.forename: Bronwyn Evelyn
authors.initials: BE
authors.lastname: Campbell
authors.forename: Filipe
authors.initials: F
authors.lastname: Dantas-Torres
authors.forename: Domenico
authors.initials: D
authors.lastname: Otranto
mesh_terms: D000818:Animals; D000947:Antigens, Helminth / Q000097:blood; D004283:Dog Diseases / Q000175:diagnosis* / Q000469:parasitology; D004285:Dogs / Q000469:parasitology; D004797:Enzyme-Linked Immunosorbent Assay; D009854:Onchocerca; D015827:Onchocerciasis, Ocular / Q000175:diagnosis / Q000662:veterinary*; D012680:Sensitivity and Specificity
chemical_list: D000947:Antigens, Helminth