title: Refractory pyoderma gangrenosum treated with infliximab in an infant.
abstract: We report the case of an 11-month-old boy with severe recalcitrant pyoderma gangrenosum refractory to prednisone, dapsone and ciclosporin. Treatment with infliximab was well tolerated, and resulted in an excellent clinical response that has been sustained for 15 months. The characteristics of this condition in children and the use of infliximab in infants are both reviewed.
authors.affiliation: Department of Dermatology, Hospital Clínico San Carlos, Madrid, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Campos-Muñoz
authors.forename: A
authors.initials: A
authors.lastname: Conde-Taboada
authors.forename: E
authors.initials: E
authors.lastname: Aleo
authors.forename: E
authors.initials: E
authors.lastname: Toledano
authors.forename: E
authors.initials: E
authors.lastname: López-Bran
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D000069285:Infliximab; D008297:Male; D017511:Pyoderma Gangrenosum / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000911:Antibodies, Monoclonal; D003879:Dermatologic Agents; D000069285:Infliximab