title: [Detection and therapy of respiratory dysfunction by implantable (cardiac) devices].
abstract: Sleep-disordered breathing (SDB) represents a common comorbidity in cardiac patients. The prevalence of obstructive sleep apnea (OSA) and central sleep apnea (CSA) is very high, particularly in patients with heart rhythm disorders and heart failure (HF). Patients with pacemakers (PM) and implantable defibrillators (ICD) including cardiac resynchronization therapy (CRT) show SDB prevalences up to 75%. However, some modern PM, ICD and CRT devices allow the detection of SDB via transthoracic impedance analysis with high sensitivity compared to polysomnographic (PSG) controls. Thus, this method could be of relevance in screening and monitoring SDB in patients with implantable cardiac devices. Preliminary studies demonstrated the possibility to treat OSA in selected patients by stimulation of the cranial nerves, especially the hypoglossal nerve. However, this requires extensive diagnostics and advanced surgical approaches including many medical disciplines and is not part of this review article. However, unilateral and transvenous stimulation of the phrenic nerve to treat central sleep apnea and Cheyne-Stokes respiration in HF patients in particular can be performed by cardiologists. This article summarizes preliminary data on the results of this promising therapy.
authors.affiliation: Klinik für Kardiologie, Herz- und Diabeteszentrum Nordrhein-Westfalen, Universitätsklinikum der Ruhr-Universität Bochum, Georgstr. 11, 32545, Bad Oeynhausen, Deutschland.
authors.forename: H
authors.initials: H
authors.lastname: Fox
authors.forename: O
authors.initials: O
authors.lastname: Oldenburg
authors.forename: G
authors.initials: G
authors.lastname: Nölker
authors.forename: D
authors.initials: D
authors.lastname: Horstkotte
authors.forename: K-J
authors.initials: KJ
authors.lastname: Gutleben
mesh_terms: D017147:Defibrillators, Implantable; D004599:Electric Stimulation Therapy / Q000379:methods*; D006801:Humans; D010138:Pacemaker, Artificial; D010992:Plethysmography, Impedance / Q000379:methods*; D012891:Sleep Apnea Syndromes / Q000175:diagnosis* / Q000628:therapy*; D016896:Treatment Outcome