title: Giant vegetation in the right ventricle caused by Staphylococcus aureus and Candida mycoderma.
abstract: BACKGROUND
  Infective endocarditis (IE) is considered a multifactorial disease. Providing an early diagnosis and invasive treatment together with effective antibiotic treatment remain critical tasks for the cardiologist and the surgeon. Right ventricular endocarditis is a rare type of endocarditis usually caused by Staphylococcus aureus and Candida mycoderma.
  
  
  METHODS
  We present a 25-year-old male patient who presented with persistent malaise, fever, cough, and anorexia after 55 days of antibiotic treatment. Lung computed tomographic scanning excluded severe lung infection. Transthoracic and transesophageal echocardiography revealed a giant vegetation in the right ventricle. Blood culture was positive for S. aureus and C. mycoderma, and antibiotic therapy was immediately applied. Considering the large burden of infected tissue, an early surgical intervention was planned. The cultures of the vegetation specimen were negative. Intraoperative and histological findings confirmed the echocardiographic diagnosis of IE.
  
  
  CONCLUSIONS
  Giant vegetations in the right ventricle caused by S. aureus and C. mycoderma are rare. In addition to medical treatment, more attention should be paid to early surgical consultation.
authors.affiliation: Division of Cardiovascular Surgery, Chengdu Military General Hospital, Chengdu, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Ouyang
authors.affiliation: Division of Cardiovascular Surgery, Chengdu Military General Hospital, Chengdu, China.
authors.forename: Xiaochen
authors.initials: X
authors.lastname: Wu
authors.affiliation: Division of Cardiovascular Surgery, Chengdu Military General Hospital, Chengdu, China.
authors.forename: Jinbao
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy*; D003131:Combined Modality Therapy; D004696:Endocarditis / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy*; D006352:Heart Ventricles / Q000382:microbiology* / Q000601:surgery; D006801:Humans; D008297:Male; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents