title: Correlation of echocardiographic epicardial fat thickness with severity of coronary artery disease in patients with acute myocardial infarction.
abstract: The aim of this study was to test the hypotheses that epicardial adipose tissue (EAT) can be a marker of severe coronary artery disease in patients with acute myocardial infarction. Overall, 373 cases who underwent coronary angiography were classified into 2 groups by SYNTAX score: low-score and high-score group. EAT was measured by transthoracic echocardiography. Obtained data were compared using Pearson correlation analyses and univariate and multiple logistic regression analysis. The results showed that EAT in the high-score group was significantly greater than in the normal group (5.6 ± 1.1 vs. 4.1 ± 1.0 mm, P < 0.01). EAT had a positive correlation with SYNTAX score (r = 0.61, P < 0.01). Receiver operating characteristic (ROC) curve analyses showed that EAT could reliably discriminate patients with high SYNTAX score (≥ 33) [AUC: 0.86, 95% confidence interval (CI): 0.822-0.898, P < 0.01]. Multivariate regression analyses showed that EAT was an independent predictor for major in-hospital events. These data showed an association between EAT and SYNTAX score.
authors.affiliation: Department of Cardiology, The Fourth People's Hospital of Jinan, The Second Affiliated Hospital of Tai Shan Medical College, Jinan, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.forename: Qiang
authors.initials: Q
authors.lastname: Liu
authors.forename: Cuixia
authors.initials: C
authors.lastname: Liu
authors.forename: Ling
authors.initials: L
authors.lastname: Sun
authors.forename: Daixu
authors.initials: D
authors.lastname: Li
authors.forename: Aihua
authors.initials: A
authors.lastname: Liu
authors.forename: Ruyi
authors.initials: R
authors.lastname: Jia
mesh_terms: D000273:Adipose Tissue / Q000000981:diagnostic imaging* / Q000473:pathology; D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000379:methods; D016022:Case-Control Studies; D015331:Cohort Studies; D017023:Coronary Angiography / Q000379:methods; D001026:Coronary Artery Bypass / Q000379:methods; D023921:Coronary Stenosis / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D004452:Echocardiography / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D010496:Pericardium / Q000000981:diagnostic imaging* / Q000473:pathology; D011237:Predictive Value of Tests; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome
keywords: coronary angiography; epicardial adipose tissue; myocardial infarction; triple-vessel disease