title: Idiopathic Thrombocytopenia and Neurologic Manifestations in A Young Female Leading to the Diagnosis of Wilson's Disease.
abstract: We present a 19-year-old patient with hematologic and neurologic manifestations associated with Wilson's disease. Idiopathic thrombocytopenia was diagnosed in October 2009. Bone marrow aspiration was normal. Gradually her neurologic and psychiatric symptoms emerged, dysarthria, writing apraxia, learning difficulties, emotionalism and eventually dystonia of hands. The serum ceruloplasmin was low, and the Kayser Fleischer's ring was positive. MRI of the brain showed abnormality in the bilateral basal ganglia, brain stem and superior cerebellar peduncles without post-contrast enhancement.
authors.affiliation: Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Seyed Mohammad Salar
authors.initials: SM
authors.lastname: Zaheryany
authors.affiliation: MD. Assistant Professor of Psychiatry, Rafsanjan University of Medical Science Department of Psychiatry, Rafsanjan, Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Bidaki
authors.affiliation: Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Nahid
authors.initials: N
authors.lastname: Hemmatian Brujeni
authors.affiliation: MD. Neurologist, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Rezvani
authors.affiliation: MD. Assistant of child and adolescence Psychiatry, Tehran University of Medical Sciences, Hazrat Ali Asghar Hospital.
authors.forename: Mitra
authors.initials: M
authors.lastname: Hakim Shooshtari
keywords: Apraxia; Kayser Fleischer's ring; Thrombocytopenia; Wilson’s disease