title: The role of mepolizumab in atopic and nonatopic severe asthma with persistent eosinophilia.
authors.affiliation: GlaxoSmithKline, Respiratory Medicine Development Center, Research Triangle Park, NC, USA hector.g.ortega@gsk.com.
authors.forename: Hector
authors.initials: H
authors.lastname: Ortega
authors.affiliation: Dept of Pulmonary and Critical Care, Yale University Medical School, Winchester Chest Clinic, 20 York Street, New Haven, CT, USA.
authors.forename: Geoffrey
authors.initials: G
authors.lastname: Chupp
authors.affiliation: Monash University and Medical Centre, Lung and Sleep, Melbourne, Australia.
authors.forename: Philip
authors.initials: P
authors.lastname: Bardin
authors.affiliation: Dept of Allergy, Hospital Arnaud de Villeneuve, Montpellier, France.
authors.forename: Arnaud
authors.initials: A
authors.lastname: Bourdin
authors.affiliation: University Paris-Sud, Faculté de Médecine, Le Kremlin-Bicêtre, France AP-HP, Service de Pneumologie, DHU Thorax Innovation, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
authors.forename: Gilles
authors.initials: G
authors.lastname: Garcia
authors.affiliation: GlaxoSmithKline, Research and Development, Stockley Park, Middlesex, UK.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Hartley
authors.affiliation: GlaxoSmithKline, Respiratory Medicine Development Center, Research Triangle Park, NC, USA.
authors.forename: Steve
authors.initials: S
authors.lastname: Yancey
authors.affiliation: University Paris-Sud, Faculté de Médecine, Le Kremlin-Bicêtre, France AP-HP, Service de Pneumologie, DHU Thorax Innovation, Hôpital Bicêtre, Le Kremlin-Bicêtre, France Inserm U999, LabEx LERMIT, Le Plessis Robinson, France.
authors.forename: Marc
authors.initials: M
authors.lastname: Humbert
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy*; D002648:Child; D004802:Eosinophilia / Q000188:drug therapy*; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000097:blood* / Q000188:drug therapy*; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology; D007249:Inflammation; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D016032:Randomized Controlled Trials as Topic; D012621:Seasons; D013147:Spirometry; D013256:Steroids / Q000627:therapeutic use; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D013256:Steroids; D007073:Immunoglobulin E; C434107:mepolizumab