title: Infectious diseases, from HCV to cpe how susceptible are we?
abstract: Infectious diseases remain a leading cause of morbidity and mortality. Still, there is substantial variation in the individual outcome when humans are exposed to potentially pathogenic micro-organisms. At least, one of the factors involved in the individual susceptibility to infections, is the genetic diversity of the host's immune response. This article gives a concise overview of the actual knowledge on the genetic mechanisms underlying human susceptibility to infectious diseases and the methods that are used to investigate it.
authors.forename: P
authors.initials: P
authors.lastname: Lacor
mesh_terms: D003141:Communicable Diseases / Q000453:epidemiology / Q000235:genetics / Q000276:immunology / Q000401:mortality; D004198:Disease Susceptibility; D004756:Enterobacteriaceae Infections / Q000453:epidemiology* / Q000235:genetics / Q000276:immunology; D005062:European Union / Q000706:statistics & numerical data; D016678:Genome; D015658:HIV Infections / Q000453:epidemiology* / Q000821:virology; D006526:Hepatitis C / Q000453:epidemiology* / Q000821:virology; D019698:Hepatitis C, Chronic / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008288:Malaria / Q000453:epidemiology* / Q000235:genetics; D008589:Meningococcal Infections / Q000453:epidemiology; D011110:Polymorphism, Genetic