title: Ecology and metabolism of the beneficial intestinal commensal bacterium Faecalibacterium prausnitzii.
abstract: Faecalibacterium prausnitzii is a major commensal bacterium, and its prevalence is often decreased in conditions of intestinal dysbiosis. The phylogenic identity of this bacterium was described only recently. It is still poorly characterized, and its specific growth requirements in the human gastrointestinal tract are not known. In this review, we consider F. prausnitzii metabolism, its ecophysiology in both humans and animals, and the effects of drugs and nutrition on its population. We list important questions about this beneficial and ubiquitous commensal bacterium that it would be valuable to answer.
authors.affiliation: INRA; Commensal and Probiotics-Host Interactions Laboratory; UMR 1319 Micalis; Jouy-en-Josas, France; AgroParisTech; UMR1319 Micalis; Jouy-en-Josas, France.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Miquel
authors.affiliation: INRA; Commensal and Probiotics-Host Interactions Laboratory; UMR 1319 Micalis; Jouy-en-Josas, France; AgroParisTech; UMR1319 Micalis; Jouy-en-Josas, France.
authors.forename: Rebeca
authors.initials: R
authors.lastname: Martín
authors.affiliation: INRA; Commensal and Probiotics-Host Interactions Laboratory; UMR 1319 Micalis; Jouy-en-Josas, France; AgroParisTech; UMR1319 Micalis; Jouy-en-Josas, France.
authors.forename: Chantal
authors.initials: C
authors.lastname: Bridonneau
authors.affiliation: INRA; Commensal and Probiotics-Host Interactions Laboratory; UMR 1319 Micalis; Jouy-en-Josas, France; AgroParisTech; UMR1319 Micalis; Jouy-en-Josas, France.
authors.forename: Véronique
authors.initials: V
authors.lastname: Robert
authors.affiliation: INRA; Commensal and Probiotics-Host Interactions Laboratory; UMR 1319 Micalis; Jouy-en-Josas, France; AgroParisTech; UMR1319 Micalis; Jouy-en-Josas, France; ERL INSERM U 1057/UMR7203; Faculté de Médecine Saint-Antoine; Université Pierre et Marie Curie (UPMC); Paris, France; Service de Gastroenterologie; Hôpital Saint-Antoine; Assistance Publique-Hôpitaux de Paris (APHP); Paris, France.
authors.forename: Harry
authors.initials: H
authors.lastname: Sokol
authors.affiliation: INRA; Commensal and Probiotics-Host Interactions Laboratory; UMR 1319 Micalis; Jouy-en-Josas, France; AgroParisTech; UMR1319 Micalis; Jouy-en-Josas, France.
authors.forename: Luis G
authors.initials: LG
authors.lastname: Bermúdez-Humarán
authors.affiliation: INRA; Commensal and Probiotics-Host Interactions Laboratory; UMR 1319 Micalis; Jouy-en-Josas, France; AgroParisTech; UMR1319 Micalis; Jouy-en-Josas, France.
authors.forename: Muriel
authors.initials: M
authors.lastname: Thomas
authors.affiliation: INRA; Commensal and Probiotics-Host Interactions Laboratory; UMR 1319 Micalis; Jouy-en-Josas, France; AgroParisTech; UMR1319 Micalis; Jouy-en-Josas, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Langella
mesh_terms: D004463:Ecology; D006094:Gram-Positive Bacteria / Q000235:genetics / Q000378:metabolism* / Q000502:physiology*; D006801:Humans; D007422:Intestines / Q000382:microbiology*
keywords: ecophysiology; medicine; metabolism; nutrition