title: Successful first round results of a Turkish breast cancer screening program with mammography in Bahcesehir, Istanbul.
abstract: BACKGROUND
  The Bahcesehir Breast Cancer Screening Project is the first organized population based breast cancer mammographic screening project in Turkey. The objective of this prospective observational study was to demonstrate the feasibility of a screening program in a developing country and to determine the appropriate age (40 or 50 years old) to start with screening in Turkish women.
  
  
  METHODS
  Between January 2009 to December 2010, a total of 3,758 women aged 40-69 years were recruited in this prospective study. Screening was conducted biannually, and five rounds were planned. After clinical breast examination (CBE), two-view mammograms were obtained. True positivity, false positivity, positive predictive values (PPV) according to ACR, cancer detection rate, minimal cancer detection rate, axillary node positivity and recall rate were calculated. Breast ultrasound and biopsy were performed in suspicious cases.
  
  
  RESULTS
  Breast biopsy was performed in 55 patients, and 18 cancers were detected in the first round. The overall cancer detection rate was 4.8 per 1,000 women. Most of the screened women (54%) and detected cancers (56%) were in women aged 40- 49. Ductal carcinoma in situ (DCIS) and stage I cancer and axillary node positivity rates were 22%, 61%, and 16.6%, respectively. The positive predictivity for biopsy was 32.7%, whereas the overall recall rate was 18.4 %.
  
  
  CONCLUSIONS
  Preliminary results of the study suggest that population based organized screening are feasible and age of onset of mammographic screening should be 40 years in Turkey.
authors.affiliation: Department of Radiology, Faculty of Medicine, Namik Kemal University, Tekirdag, Turkey E-mail : drbeyza@hotmail.com.
authors.forename: Arda
authors.initials: A
authors.lastname: Kayhan
authors.forename: Sibel Ozkan
authors.initials: SO
authors.lastname: Gurdal
authors.forename: Nilufer
authors.initials: N
authors.lastname: Ozaydin
authors.forename: Neslihan
authors.initials: N
authors.lastname: Cabioglu
authors.forename: Enis
authors.initials: E
authors.lastname: Ozturk
authors.forename: Beyza
authors.initials: B
authors.lastname: Ozcinar
authors.forename: Erkin
authors.initials: E
authors.lastname: Aribal
authors.forename: Vahit
authors.initials: V
authors.lastname: Ozmen
mesh_terms: D000328:Adult; D000368:Aged; D001365:Axilla / Q000473:pathology; D001940:Breast / Q000473:pathology / Q000601:surgery; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000517:prevention & control; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000175:diagnosis; D055088:Early Detection of Cancer; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis / Q000175:diagnosis; D008327:Mammography; D008403:Mass Screening; D008875:Middle Aged; D011446:Prospective Studies; D014421:Turkey / Q000453:epidemiology