title: Advances in research on metalloproteins.
abstract: Metal ions play essential roles in biological processes. Ions such as K(+) and Na(+) are important in ion transport, and Mg(2+), Ca(2+), and Zn(2+) are important chelators in many processes, including phosphotransfer and harvesting of light for energy metabolism. The transition metals readily undergo one-electron chemistry, and in this capacity they function uniquely in biological processes such as long-range and inner sphere electron transfer. They also facilitate many one-electron chemical reactions involving free radical intermediates. Iron, being the dominant element in the earth and a transition metal, most frequently participates in biological one-electron chemistry.
authors.affiliation: Department of Biochemistry, Institute for Enzyme Research, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI, 53706, USA, frey@biochem.wisc.edu.
authors.forename: Perry A
authors.initials: PA
authors.lastname: Frey
mesh_terms: D000473:Alkanes / Q000378:metabolism; D008667:Metalloproteins / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism; D012106:Research; D028561:Transition Elements / Q000378:metabolism
chemical_list: D000473:Alkanes; D008667:Metalloproteins; D028561:Transition Elements; D010100:Oxygen