title: Venoarterial modified ultrafiltration versus conventional arteriovenous modified ultrafiltration during cardiopulmonary bypass surgery.
abstract: OBJECTIVE
  Different types of modified ultrafiltration (MUF) systems evaluated showed that none of the MUF techniques adhered to the normal venous to arterial blood flow dynamics. This study compared a conventional arteriovenous modified ultrafiltration (AVMUF) system to a custom- designed venoarterial modified ultrafiltration (VAMUF) system.
  
  
  METHODS
  Randomized, controlled clinical study conducted at the Northwest Armed Forces Military hospital in Tabuk, Saudi Arabia.
  
  
  METHODS
  Sixty patients who underwent MUF during the years 2007 and 2009 were divided into 2 groups: the AVMUF (n=30) and the VAMUF (n=30) groups. MUF was performed for a mean time of 12 minutes in both groups. In AVMUF, blood was removed from the aorta, hemoconcentrated, and infused into the right atrium (RA). In VAMUF, blood flow was from the RA through a hemoconcentrator and re-infused into the aorta.
  
  
  RESULTS
  Results of the study showed that the VAMUF group required a shorter ventilation time (P < .001), in.tensive care unit (ICU) (P=.003), and hospital stay (P=.007) than the AVMUF group. Results also demonstrated a lower percentage of fluid balance (P=.008) in the VAMUF group. The systolic (P < .001) and mean blood pres.sures (P < .001) were significantly higher after VAMUF, with a decrease in heart rate (P < .001) and central venous pressure (P=.002). The VAMUF group showed a significantly greater decrease of creatinine (P < .001), serum lactacte (P < .001), and uric acid (P < .027) over time with no significant differences in oximetry.
  
  
  CONCLUSIONS
  Results prove that VAMUF is a more physiological technique than AVMUF.
authors.forename: Rakesh
authors.initials: R
authors.lastname: Mohanlall
authors.affiliation: Prof. Jamila Adam, Department of Biomedical Clinical Technology,, Faculty of Health Sciences Biomedical and Clinical Technology,, Durban University of Technology,, Durban, KZN 1334 South Africa, T: +27-373-5291, F: +27-373-5295, wnsr65@hotmail.com.
authors.forename: Jamila
authors.initials: J
authors.lastname: Adam
authors.forename: Arto
authors.initials: A
authors.lastname: Nemlander
mesh_terms: D000328:Adult; D000818:Animals; D002315:Cardiopulmonary Bypass / Q000379:methods*; D005260:Female; D006041:Goats; D006439:Hemodynamics; D006440:Hemofiltration / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012529:Saudi Arabia