title: Automated assessment of the quality of diffusion tensor imaging data using color cast of color-encoded fractional anisotropy images.
abstract: Diffusion tensor imaging (DTI) data often suffer from artifacts caused by motion. These artifacts are especially severe in DTI data from infants, and implementing tight quality controls is therefore imperative for DTI studies of infants. Currently, routine procedures for quality assurance of DTI data involve the slice-wise visual inspection of color-encoded, fractional anisotropy (CFA) images. Such procedures often yield inconsistent results across different data sets, across different operators who are examining those data sets, and sometimes even across time when the same operator inspects the same data set on two different occasions. We propose a more consistent, reliable, and effective method to evaluate the quality of CFA images automatically using their color cast, which is calculated on the distribution statistics of the 2D histogram in the color space as defined by the International Commission on Illumination (CIE) on lightness and a and b (LAB) for the color-opponent dimensions (also known as the CIELAB color space) of the images. Experimental results using DTI data acquired from neonates verified that this proposed method is rapid and accurate. The method thus provides a new tool for real-time quality assurance for DTI data.
authors.affiliation: Center for Developmental Neuropsychiatry, Department of Psychiatry, Columbia University & New York State Psychiatric Institute, New York, NY 10032, USA.
authors.forename: Xiaofu
authors.initials: X
authors.lastname: He
authors.affiliation: Center for Developmental Neuropsychiatry, Department of Psychiatry, Columbia University & New York State Psychiatric Institute, New York, NY 10032, USA.
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.affiliation: Key laboratory of Brain Functional Genomics (MOE & STCSM), Institute of Cognitive Neuroscience, School of Psychology and Cognitive Science, East China Normal University, Shanghai, 20062, China.
authors.forename: Xuzhou
authors.initials: X
authors.lastname: Li
authors.affiliation: Center for Developmental Neuropsychiatry, Department of Psychiatry, Columbia University & New York State Psychiatric Institute, New York, NY 10032, USA.
authors.forename: Qingli
authors.initials: Q
authors.lastname: Li
authors.affiliation: MRI Unit, Department of Psychiatry, Columbia University & New York State Psychiatric Institute, New York, NY 10032, USA.
authors.forename: Feng
authors.initials: F
authors.lastname: Liu
authors.affiliation: Columbia Center for Children's Environmental Health, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
authors.forename: Virginia A
authors.initials: VA
authors.lastname: Rauh
authors.affiliation: Center for Developmental Neuropsychiatry, Department of Psychiatry, Columbia University & New York State Psychiatric Institute, New York, NY 10032, USA; Key laboratory of Brain Functional Genomics (MOE & STCSM), Institute of Cognitive Neuroscience, School of Psychology and Cognitive Science, East China Normal University, Shanghai, 20062, China.
authors.forename: Dazhi
authors.initials: D
authors.lastname: Yin
authors.affiliation: Center for Developmental Neuropsychiatry, Department of Psychiatry, Columbia University & New York State Psychiatric Institute, New York, NY 10032, USA.
authors.forename: Ravi
authors.initials: R
authors.lastname: Bansal
authors.affiliation: MRI Unit, Department of Psychiatry, Columbia University & New York State Psychiatric Institute, New York, NY 10032, USA.
authors.forename: Yunsuo
authors.initials: Y
authors.lastname: Duan
authors.affiliation: MRI Unit, Department of Psychiatry, Columbia University & New York State Psychiatric Institute, New York, NY 10032, USA.
authors.forename: Alayar
authors.initials: A
authors.lastname: Kangarlu
authors.affiliation: Center for Developmental Neuropsychiatry, Department of Psychiatry, Columbia University & New York State Psychiatric Institute, New York, NY 10032, USA.
authors.forename: Bradley S
authors.initials: BS
authors.lastname: Peterson
authors.affiliation: Center for Developmental Neuropsychiatry, Department of Psychiatry, Columbia University & New York State Psychiatric Institute, New York, NY 10032, USA. Electronic address: dx2103@columbia.edu.
authors.forename: Dongrong
authors.initials: D
authors.lastname: Xu
mesh_terms: D000465:Algorithms; D016880:Anisotropy; D016477:Artifacts; D001921:Brain / Q000166:cytology*; D003116:Color; D003124:Colorimetry / Q000379:methods; D056324:Diffusion Tensor Imaging / Q000379:methods*; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D007231:Infant, Newborn; D008297:Male; D009038:Motion; D009413:Nerve Fibers, Myelinated / Q000648:ultrastructure*; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
keywords: CIELAB color space; Color-encoded fractional anisotropy (CFA); Diffusion tensor imaging (DTI); Quality assessment