title: Two cases of methaemoglobinaemia secondary to amyl nitrate use.
abstract: We wish to report two cases of methaemoglobinaemia secondary to amyl nitrate use. A 55-year-old male presented with saturations in the mid 80s despite FiO2 of 1.0 and GCS 10 and a 22-year-old female who presented with fluctuating GCS and a slate grey colour. Both were found to have high levels of metheamoglobinaemia on ABG, were treated with methylene blue and made excellent recoveries. These cases illustrate the risk of methaemoglobinaemia secondary to amyl nitrate. Appropriate and prompt management can lead to very good outcomes.
authors.forename: R
authors.initials: R
authors.lastname: Nee
authors.forename: M
authors.initials: M
authors.lastname: Fitzgerald
mesh_terms: D004791:Enzyme Inhibitors / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008708:Methemoglobinemia / Q000139:chemically induced* / Q000188:drug therapy; D008751:Methylene Blue / Q000008:administration & dosage; D008875:Middle Aged; D009566:Nitrates / Q000506:poisoning*; D000439:Pentanols / Q000506:poisoning*; D055815:Young Adult
chemical_list: D004791:Enzyme Inhibitors; D009566:Nitrates; D000439:Pentanols; D008751:Methylene Blue; C036285:amyl nitrate