title: Current perspectives for management of acute respiratory insufficiency in premature infants with acute respiratory syndrome.
abstract: Current perspectives for management of acute respiratory insufficiency in premature infants with acute respiratory syndrome and the pathology of acute respiratory insufficiency in the preterm infant, including the current therapy modalities on disposition are presented. Since the therapeutical challenge and primary clinical goal are to normalize ventilation ratio and lung perfusion, when respiratory insufficiency occurs, it is very important to introduce the respiratory support as soon possible, in order to reduce development of pulmonary cyanosis and edema, and intrapulmonary or intracardial shunts. A characteristic respiratory instability that reflects through fluctuations in gas exchange and ventilation is often present in premature infants. Adapting the respiratory support on a continuous basis to the infant's needs is challenging and not always effective. Although a large number of ventilation strategies for the neonate are available, there is a need for additional consensus on management of acute respiratory distress syndrome in pediatric population lately redefined by Berlin definition criteria, in order to efficiently apply various modes of respiratory support in daily pediatrician clinical use.
authors.affiliation: Department of Anesthesiology, China-Japan Union Hospital of Jilin University, Changchun, 130033, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Chen
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhang
authors.forename: Long-Yun
authors.initials: LY
authors.lastname: Li
mesh_terms: D006801:Humans; D007234:Infant, Premature; D012127:Respiratory Distress Syndrome, Newborn / Q000150:complications*; D012131:Respiratory Insufficiency / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy