title: Two new steroidal saponins from the rhizomes of Dioscorea zingiberensis.
abstract: OBJECTIVE
  To investigate the chemical constituents of Dioscorea zingiberensis C. H. Wright.
  
  
  METHODS
  The compounds were isolated by various chromatographic techniques, and the structures of the new steroidal saponins were elucidated by extensive 1D- and 2D-NMR, MS, and IR spectral analysis.
  
  
  RESULTS
  The 70% EtOH extract of the rhizomes of Dioscorea zingiberensis afforded two new steroidal saponins, zingiberenosides A (1) and B (2), along with eight known analogues, 3β, 26-dihydroxy-25(R)-furosta-Δ(5, 20(22))-diene-3-O-α-L- rhamnopyranosyl-(1→2)-O-β-D-glucopyranoside (3), methyl parvifloside (4), deltoside (5), methyl deltoside (6), zingiberensis new saponin (7), deltonin (8), progenin III (9) and diosgenin-diglucoside (10).
  
  
  CONCLUSIONS
  Two new steroidal saponins were isolated from Dioscorea zingiberensis and their structures determined.
authors.affiliation: Research Institute of Traditional Chinese Medicine, Yangtze River Pharmaceutical Group Co., Ltd., Taizhou, 225321, China.
authors.forename: Lu
authors.initials: L
authors.lastname: Zheng
authors.affiliation: Research Institute of Traditional Chinese Medicine, Yangtze River Pharmaceutical Group Co., Ltd., Taizhou, 225321, China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100029, China.
authors.forename: Jia-Yu
authors.initials: JY
authors.lastname: Zhang
authors.affiliation: Research Institute of Traditional Chinese Medicine, Yangtze River Pharmaceutical Group Co., Ltd., Taizhou, 225321, China.
authors.forename: Min
authors.initials: M
authors.lastname: Song
authors.affiliation: Research Institute of Traditional Chinese Medicine, Yangtze River Pharmaceutical Group Co., Ltd., Taizhou, 225321, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Yuan
authors.affiliation: Research Institute of Traditional Chinese Medicine, Yangtze River Pharmaceutical Group Co., Ltd., Taizhou, 225321, China.
authors.forename: Yan-Jiao
authors.initials: YJ
authors.lastname: Xiao
authors.affiliation: Research Institute of Traditional Chinese Medicine, Yangtze River Pharmaceutical Group Co., Ltd., Taizhou, 225321, China. Electronic address: tingxiang39@163.com.
authors.forename: Ting
authors.initials: T
authors.lastname: Xiang
mesh_terms: D027742:Dioscorea / Q000737:chemistry*; D004144:Diosgenin / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D013150:Spirostans / Q000737:chemistry / Q000302:isolation & purification; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D010936:Plant Extracts; D012503:Saponins; D013150:Spirostans; D013256:Steroids; C509382:diosgenin-diglucoside; C016347:deltonin; D004144:Diosgenin
keywords: Dioscorea zingiberensis; Dioscoreaceae; Steroidal saponins; Zingiberenoside