title: Fixed rate of blood component improves the survival rate of patients in massive transfusion.
abstract: The aim of this study was to examine the manner in which varying proportions of serum and red blood cells (RBC) in massive blood transfusion affect the survival rates of patients with severe blood loss. Massive transfusion (MT) was determined as receiving ≥10 units of red blood cells in 24 h. The electronic medical records and blood transfusion information for the period January, 2002 to December, 2011 of patients with MT were examined. Moreover, we calculated the ratio of blood components and examined their correlation with survival. In total, 1,658 patients underwent MT during the period 2002-2011, with an overall of 28,030 units RBC, accounting for 2.8% of the total blood transfusion. In conclusion, fixing blood-component ratios has the potential to help improve survival rate in MT.
authors.affiliation: Department of Blood Transfusion, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710032;
authors.forename: Wen-Ting
authors.initials: WT
authors.lastname: Wang
authors.affiliation: School of Life Sciences and Technology, Xidian University, Xi'an, Shaanxi 710071, P.R. China.
authors.forename: Yong-Hua
authors.initials: YH
authors.lastname: Zhan
authors.affiliation: Department of Blood Transfusion, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710032;
authors.forename: Xing-Bin
authors.initials: XB
authors.lastname: Hu
authors.affiliation: Department of Blood Transfusion, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710032;
authors.forename: Shi-Jie
authors.initials: SJ
authors.lastname: Mu
authors.affiliation: Department of Blood Transfusion, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710032;
authors.forename: Qun-Xing
authors.initials: QX
authors.lastname: An
authors.affiliation: Department of Blood Transfusion, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710032;
authors.forename: Zhi-Xin
authors.initials: ZX
authors.lastname: Liu
authors.affiliation: Department of Blood Transfusion, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710032;
authors.forename: Xian-Qing
authors.initials: XQ
authors.lastname: Zhang
keywords: blood loss in trauma; infusion proportion; massive transfusion