title: Microfluidic spinning of micro- and nano-scale fibers for tissue engineering.
abstract: Microfluidic technologies have recently been shown to hold significant potential as novel tools for producing micro- and nano-scale structures for a variety of applications in tissue engineering and cell biology. Over the last decade, microfluidic spinning has emerged as an advanced method for fabricating fibers with diverse shapes and sizes without the use of complicated devices or facilities. In this critical review, we describe the current development of microfluidic-based spinning techniques for producing micro- and nano-scale fibers based on different solidification methods, platforms, geometries, or biomaterials. We also highlight the emerging applications of fibers as bottom-up scaffolds such as cell encapsulation or guidance for use in tissue engineering research and clinical practice.
authors.affiliation: Biotechnology-Medical Science, KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 136-701, Republic of Korea.
authors.forename: Yesl
authors.initials: Y
authors.lastname: Jun
authors.forename: Edward
authors.initials: E
authors.lastname: Kang
authors.forename: Sukyoung
authors.initials: S
authors.lastname: Chae
authors.forename: Sang-Hoon
authors.initials: SH
authors.lastname: Lee
mesh_terms: D000818:Animals; D006801:Humans; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation* / Q000379:methods*; D057139:Nanofibers / Q000737:chemistry*; D023822:Tissue Engineering / Q000295:instrumentation* / Q000379:methods*