title: Do atypical femoral fractures in patients with prolonged alendronate treatment heal?
abstract: Osteoporosis, which is a major health problem, may have an adverse impact on the economic status of the society and the quality of the life of the patients. Long-term alendronate use may cause an increased susceptibility to fractures with an increased risk of delayed union. In this article, we describe two patients on long-term alendronate therapy which were treated for atypical femoral fractures healed with surgical treatment plus calcium, vitamin D support, and alendronate discontinuation.
authors.affiliation: Department of Orthopedics and Traumatology, Medicine Faculty of Gazi University, 06500 Beşevler, Ankara, Turkey. satikmd@gmail.com.
authors.forename: O Sahap
authors.initials: OS
authors.lastname: Atik
authors.forename: Akif M
authors.initials: AM
authors.lastname: Oztürk
authors.forename: Cemalettin
authors.initials: C
authors.lastname: Kunat
authors.forename: Mehmet
authors.initials: M
authors.lastname: Cetinkaya
authors.forename: Yiğit
authors.initials: Y
authors.lastname: Kaptan
mesh_terms: D000328:Adult; D000368:Aged; D019386:Alendronate / Q000008:administration & dosage / Q000009:adverse effects; D050071:Bone Density Conservation Agents / Q000008:administration & dosage / Q000009:adverse effects; D002118:Calcium / Q000378:metabolism; D005260:Female; D005264:Femoral Fractures / Q000209:etiology / Q000378:metabolism / Q000601:surgery; D005592:Fracture Fixation / Q000009:adverse effects / Q000379:methods; D006801:Humans; D010024:Osteoporosis / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D011183:Postoperative Complications / Q000378:metabolism; D016896:Treatment Outcome; D014807:Vitamin D / Q000378:metabolism; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D050071:Bone Density Conservation Agents; D014807:Vitamin D; D002118:Calcium; D019386:Alendronate