title: [Cytological features and chemiluminescent activity of phagocytic cells in bronchial lavage of elderly patients with bronchial asthma].
abstract: The aim of the study was to investigate cytological features and chemo luminescent activity of bronchial lavage phagocytic cells in 58 patients (28 of them are over 60 years old and 25 patients younger than 60 years) with bronchial asthma (BA) before and after achievement of medicinal disease control. Bronchial inflammation process in elderly patients (> 60 years) was characterized by significant higher content of neutrophils and lymphocytes as well as lower proportion of alveolar macrophages. Chemo luminescent responses of bronchial lavage phagocyte cells in patients with BA were unidirectional in two comparative aging groups, albeit with quantitative differences. In conclusion, respiratory tract inflammatory process in elderly patients with BA is characterized by less pronounced involvement of effector cells, lower chemo luminescent activity of phagocytes in comparison with similar parameters in the patients younger than 60 years old.
authors.forename: Iu I
authors.initials: IuI
authors.lastname: Grinshteĭn
authors.forename: V A
authors.initials: VA
authors.lastname: Shestovitskiĭ
authors.forename: A V
authors.initials: AV
authors.lastname: Maksimova
authors.forename: N V
authors.initials: NV
authors.lastname: Topol'skaia
authors.forename: A I
authors.initials: AI
authors.lastname: Aristov
authors.forename: I I
authors.initials: II
authors.lastname: Cherkashina
mesh_terms: D000368:Aged; D000375:Aging / Q000473:pathology*; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use; D001249:Asthma / Q000175:diagnosis* / Q000188:drug therapy; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology*; D018450:Disease Progression; D005260:Female; D006801:Humans; D007249:Inflammation / Q000473:pathology; D007958:Leukocyte Count; D008163:Luminescent Measurements / Q000379:methods*; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000473:pathology; D010586:Phagocytes / Q000473:pathology*
chemical_list: D018927:Anti-Asthmatic Agents