title: Craniofacial characteristics of successful responders to mandibular advancement splint therapy: a pilot study.
abstract: Cephalometric variables that can be used to identify patients with obstructive sleep apnoea who are suitable for mandibular advancement splints and surgical maxillomandibular advancement are lacking. The aim of this pilot study was to describe the craniofacial characteristics of patients whose symptoms of obstructive sleep apnoea were successfully treated with mandibular advancement splints and who were subsequently considered for maxillomandibular advancement. We retrospectively compared the craniofacial characteristics of our patients with data from 2 previously published studies. There were significant differences between the 2 groups for ANB (p<0.000), overjet (p<0.0001), Go-Me (p<0.0002), and ANS-PNS (p<0.0009). Patients, whose symptoms improve with the use of mandibular advancement splints and are potential candidates for maxillomandibular advancement, may have unique craniofacial features consisting of bimaxillary retrusion characterised by a shorter maxilla and mandible, and a greater class II skeletal tendency. The results of this study should be viewed as a pilot. Further research is required.
authors.affiliation: Kings College Hospital NHS Foundation Trust. Electronic address: jadbinder.seehra@nhs.net.
authors.forename: Jadbinder
authors.initials: J
authors.lastname: Seehra
authors.affiliation: School of Oral and Dental Sciences, Bristol Dental Hospital, University of Bristol and Kings College London Dental Institute at Guy's, King's College and St Thomas' Hospitals.
authors.forename: Martyn
authors.initials: M
authors.lastname: Sherriff
authors.affiliation: Queen Victoria Hospital NHS Foundation Trust, Holtye Road, East Grinstead, West Sussex RH19 3DZ, UK.
authors.forename: Lindsay
authors.initials: L
authors.lastname: Winchester
mesh_terms: D000328:Adult; D059925:Anatomic Landmarks / Q000473:pathology; D002508:Cephalometry / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008312:Malocclusion, Angle Class II / Q000473:pathology; D008334:Mandible / Q000473:pathology; D019186:Mandibular Advancement / Q000295:instrumentation*; D008437:Maxilla / Q000473:pathology; D008875:Middle Aged; D009295:Nasal Bone / Q000473:pathology; D009971:Orthodontics, Corrective / Q000379:methods; D056948:Orthognathic Surgical Procedures / Q000379:methods; D057887:Overbite / Q000473:pathology; D010159:Palate / Q000473:pathology; D010865:Pilot Projects; D017286:Polysomnography / Q000379:methods; D012189:Retrospective Studies; D020181:Sleep Apnea, Obstructive / Q000473:pathology / Q000628:therapy*; D013165:Splints; D016896:Treatment Outcome
keywords: Craniofacial; Maxillomandibular advancement; Morphology; Obstructive sleep apnoea