title: Helical folding of α/β-peptides containing β-amino acids with an eight-membered ring constraint.
abstract: αβα-Tripeptide that contains a cyclic β-amino acid with an eight-membered ring, a cis-2-aminocyclooct-5-enecarboxylic acid (cis-ACOE) or a cis-2-aminocyclooctanecarboxylic acid (cis-ACOC) displayed an 11/9-helical turn in the crystal state. The related α/β-peptide oligomers were shown to adopt 11/9-helical conformations in solution.
authors.affiliation: Department of Chemistry, Yonsei University, Seoul 120-749, Republic of Korea.
authors.forename: Woohyung
authors.initials: W
authors.lastname: Lee
authors.forename: Sunmi
authors.initials: S
authors.lastname: Kwon
authors.forename: Philjae
authors.initials: P
authors.lastname: Kang
authors.forename: Ilia A
authors.initials: IA
authors.lastname: Guzei
authors.forename: Soo Hyuk
authors.initials: SH
authors.lastname: Choi
mesh_terms: D000598:Amino Acids, Cyclic / Q000737:chemistry*; D002942:Circular Dichroism; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D008958:Models, Molecular; D010446:Peptide Fragments / Q000737:chemistry*; D017510:Protein Folding; D017433:Protein Structure, Secondary; D013055:Spectrophotometry, Infrared
chemical_list: D000598:Amino Acids, Cyclic; D010446:Peptide Fragments