title: HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells.
abstract: The n-butanol extract of the roots of Glyphaea brevis was analysed. HPLC analysis suggested the presence of phenolic compounds like protocatechuic acid (PCA). The extract showed moderate cytotoxic activity against C6 glioma cells (EC50 > 1 mg/ml).
authors.affiliation: Laboratoire de Chimie Bioorganique et de Substances Naturelles (LCBOSN), UFR-SFA, Université Nangui Abrogoua, 02 BP 801 Abidjan 02, Côte d'Ivoire.
authors.forename: Koffi Marcel
authors.initials: KM
authors.lastname: Konan
authors.affiliation: Laboratoire de Chimie Bioorganique et de Substances Naturelles (LCBOSN), UFR-SFA, Université Nangui Abrogoua, 02 BP 801 Abidjan 02, Côte d'Ivoire.
authors.forename: Janat Akhanovna
authors.initials: JA
authors.lastname: Mamyrbekova-Bekro
authors.affiliation: UMR 5253, ICG Montpellier, Equipe AM2N, ENSCM, 8, rue de l'Ecole Normale, 34296 Montpellier cedex 5, France. ; INSERM U-1051, Institut des Neurosciences de Montpellier, 80 rue Augustin Fliche 34091 Montpellier, France.
authors.forename: Norbert
authors.initials: N
authors.lastname: Bakalara
authors.affiliation: INSERM U-1051, Institut des Neurosciences de Montpellier, 80 rue Augustin Fliche 34091 Montpellier, France.
authors.forename: David
authors.initials: D
authors.lastname: Virieux
authors.affiliation: INSERM U-1051, Institut des Neurosciences de Montpellier, 80 rue Augustin Fliche 34091 Montpellier, France.
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Pirat
authors.affiliation: Laboratoire de Chimie Bioorganique et de Substances Naturelles (LCBOSN), UFR-SFA, Université Nangui Abrogoua, 02 BP 801 Abidjan 02, Côte d'Ivoire.
authors.forename: Yves-Alain
authors.initials: YA
authors.lastname: Bekro
keywords: C6 Cells; Cytotoxicity; Glyphaea brevis; HPLC; Protocatechuic acid