title: Covalently linked plasticizers: triazole analogues of phthalate plasticizers prepared by mild copper-free “click” reactions with azide-functionalized PVC.
abstract: Copper-free azide-alkyne click chemistry is utilized to covalently modify polyvinyl chloride(PVC). Phthalate plasticizer mimics di(2-ethylhexyl)-1H-triazole-4,5 dicarboxylate (DEHT), di(nbutyl)-1H-1,2,3-triazole-4,5-dicarboxylate (DBT), and dimethyl-1H-triazole-4,5-dicarboxylate(DMT) are covalently attached to PVC. DEHT, DBT, and DMT have similar chemical structures to traditional plasticizers di(2-ethylhexyl) phthalate (DEHP), di(n-butyl) phthalate (DBP), and dimethyl phthalate (DMP), but pose no danger of leaching from the polymer matrix and forming small endocrine disrupting chemicals. The synthesis of these covalent plasticizers is expected to be scalable, providing a viable alternative to the use of phthalates, thus mitigating dangers to human health and the environment.
authors.forename: Aruna
authors.initials: A
authors.lastname: Earla
authors.forename: Rebecca
authors.initials: R
authors.lastname: Braslau
mesh_terms: D001386:Azides / Q000737:chemistry*; D057930:Click Chemistry; D015394:Molecular Structure; D010795:Phthalic Acids / Q000737:chemistry*; D010968:Plasticizers / Q000737:chemistry*; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D011143:Polyvinyl Chloride / Q000737:chemistry*; D014230:Triazoles / Q000737:chemistry*
chemical_list: D001386:Azides; D010795:Phthalic Acids; D010968:Plasticizers; D011108:Polymers; D014230:Triazoles; C032279:phthalic acid; D011143:Polyvinyl Chloride