title: Five cases of interstitial lung disease after leflunomide was combined with methotrexate therapy.
authors.affiliation: Department of Medicine, University of Eastern Finland , Kuopio , Finland.
authors.forename: J
authors.initials: J
authors.lastname: Rutanen
authors.forename: A
authors.initials: A
authors.lastname: Kononoff
authors.forename: L
authors.initials: L
authors.lastname: Arstila
authors.forename: P
authors.initials: P
authors.lastname: Elfving
authors.forename: H
authors.initials: H
authors.lastname: Koskela
authors.forename: O
authors.initials: O
authors.lastname: Kaipiainen-Seppänen
mesh_terms: D000368:Aged; D001172:Arthritis, Rheumatoid / Q000175:diagnosis / Q000188:drug therapy*; D018450:Disease Progression; D004347:Drug Interactions; D004359:Drug Therapy, Combination / Q000009:adverse effects; D005260:Female; D005387:Finland; D006801:Humans; D015994:Incidence; D007555:Isoxazoles / Q000009:adverse effects* / Q000627:therapeutic use; D000077339:Leflunomide; D017563:Lung Diseases, Interstitial / Q000139:chemically induced* / Q000453:epidemiology* / Q000628:therapy; D008297:Male; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D011379:Prognosis; D018570:Risk Assessment; D012494:Sampling Studies; D015996:Survival Rate
chemical_list: D007555:Isoxazoles; D000077339:Leflunomide; D008727:Methotrexate