title: AMP kinase in exercise adaptation of skeletal muscle.
abstract: Regular physical exercise has undisputed health benefits in the prevention and the treatment of many diseases. Understanding the mechanisms that regulate adaptations to exercise training therefore has obvious clinical perspectives. Several lines of evidence suggest that the AMP-activated protein kinase (AMPK) has a central role as a master metabolic regulator in skeletal muscle. Exercise is a potent activator of AMPK, and AMPK signaling can play a key part in regulating protein turnover during and after exercise training.
authors.affiliation: Research Laboratory for Biochemical Pathology, Institute for Clinical Medicine, Aarhus University, Denmark; Department of Molecular Medicine, Aarhus University Hospital, Denmark. Electronic address: Niels.Jessen@ki.au.dk.
authors.forename: Niels
authors.initials: N
authors.lastname: Jessen
authors.affiliation: Research Laboratory for Biochemical Pathology, Institute for Clinical Medicine, Aarhus University, Denmark.
authors.forename: Elias I O
authors.initials: EI
authors.lastname: Sundelin
authors.affiliation: Research Laboratory for Biochemical Pathology, Institute for Clinical Medicine, Aarhus University, Denmark.
authors.forename: Andreas Buch
authors.initials: AB
authors.lastname: Møller
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology*; D000263:Adenylate Kinase / Q000502:physiology*; D000818:Animals; D015444:Exercise / Q000502:physiology*; D006801:Humans; D018482:Muscle, Skeletal / Q000201:enzymology*
chemical_list: D000263:Adenylate Kinase