title: SUZUKI-MIYAURA COUPLING REACTIONS OF 3,5-DICHLORO-1,2,4-THIADIAZOLE.
abstract: 3,5-Dichloro-1,2,4-thiadiazole was allowed to react with different arylboronic acids under different Suzuki-Miyaura coupling conditions: at room temperature 5-aryl-3-chloro-1,2,4-thiadiazoles were obtained and at toluene reflux temperature the products were 3,5-diaryl-1,2,4-thiadiazoles. Sequential coupling reactions lead to 3,5-diaryl-1,2,4-thiadiazoles with non-identical aryl groups. The structure of 3-methoxy-5-(4-methoxyphenyl)-1,2,4-thiadiazole was established from X-ray crystallographic data.
authors.affiliation: Department of Chemistry, Georgia State University, Atlanta, GA, 30303, U. S. A. ; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
authors.forename: Abdelbasset A
authors.initials: AA
authors.lastname: Farahat
authors.affiliation: Department of Chemistry, Georgia State University, Atlanta, GA, 30303, U. S. A.
authors.forename: David W
authors.initials: DW
authors.lastname: Boykin