title: Pulmonary sequestration: a (131)I whole body scintigraphy false-positive result.
abstract: A 35-year-old woman affected by a well-differentiated papillary thyroid carcinoma was referred to our hospital to perform a (131)Iodine ((131)I) whole body scintigraphy for restaging purpose. The patient had been previously treated with total thyroidectomy and three subsequent doses of (131)I for the ablation of a remnant jugular tissue and a suspected metastatic focus at the superior left hemi-thorax. In spite of the previous treatments with (131)I, planar and tomographic images showed the persistence of an area of increased uptake at the superior left hemi-thorax. This finding prompted the surgical resection of the lesion. Histological examination of the surgical specimen showed the presence of a pulmonary tissue consistent with pulmonary sequestration. Even though rare, pulmonary sequestration should be included in the potential causes of false-positive results of radioiodine scans.
authors.forename: Elena Giulia
authors.initials: EG
authors.lastname: Spinapolice
authors.forename: S
authors.initials: S
authors.lastname: Chytiris
authors.forename: C
authors.initials: C
authors.lastname: Fuccio
authors.forename: P
authors.initials: P
authors.lastname: Leporati
authors.forename: G
authors.initials: G
authors.lastname: Volpato
authors.forename: L
authors.initials: L
authors.lastname: Villani
authors.forename: G
authors.initials: G
authors.lastname: Trifirò
authors.forename: L
authors.initials: L
authors.lastname: Chiovato
mesh_terms: D000328:Adult; D001998:Bronchopulmonary Sequestration / Q000000981:diagnostic imaging*; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging
chemical_list: D007457:Iodine Radioisotopes