title: New diterpenes from Azorella spinosa.
abstract: Two new diterpenes,2-acetoxy-13-hydroxy-mulin-11-ene and 2-acetoxy-mulin-11, 13-diene,have been isolated from the aerial parts of Azorella spinosa and their structures determined by spectroscopic and conventional chemical methods. Furthermore, 2, 13-dihydroxy-mulin-11-ene was obtained using a basic hydrolysis of the first compound. Two diterpenes reported for other Azorella species have also been found, namely mulinolic acid and 13beta-hydroxyazorellane, as well as the triterpene lactone of ursolic acid,quercetin, and 7-hydroxycoumarin. The compounds were evaluated using antibacterial, antioxidant and enzymatic assays; no significant activity was detected.
authors.forename: Luis
authors.initials: L
authors.lastname: Astudillo
authors.forename: Margarita
authors.initials: M
authors.lastname: Gutiérrez
authors.forename: Luisa
authors.initials: L
authors.lastname: Quesada
authors.forename: Aurelio
authors.initials: A
authors.lastname: San-Martín
authors.forename: Luis
authors.initials: L
authors.lastname: Espinoza
authors.forename: Patricio
authors.initials: P
authors.lastname: Peñailillo
mesh_terms: D019661:Apiaceae / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure
chemical_list: D004224:Diterpenes