title: Passive smoke exposure was related to mean platelet volume in never-smokers.
abstract: OBJECTIVE
  To investigate the effect of passive smoking on the changes in mean platelet volume (MPV) in healthy adults.
  
  
  METHODS
  Participants (N = 17,825) were drawn from the Dongfeng-Tongji cohort. Multiple logistic regression analysis was used to examine relationships between MPV and selected variables among subgroups of MPV clarified by the MPV reference range for Chinese adults.
  
  
  RESULTS
  Female never smokers exposed to passive smoke ≥ 60 minutes every day (OR: 1.471, 95%CI: 1.147-1.886) or ≥ 30 years had a higher risk of having low MPV (OR: 1.260, 95%CI: 1.004-1.583).
  
  
  CONCLUSIONS
  Certain duration of passive smoke exposure (≥ 60 minutes/day or ≥ 30 years) was associated with higher risk of having low MPV in female never smokers.
authors.affiliation: Department of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China.
authors.forename: Chuanyao
authors.initials: C
authors.lastname: Liu
authors.affiliation: Department of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China. jyuan@tjh.tjmu.edu.cn.
authors.forename: Yuqing
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Department of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China.
authors.forename: Meian
authors.initials: M
authors.lastname: He
authors.affiliation: Department of Food Science and Technology, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China.
authors.forename: Ping
authors.initials: P
authors.lastname: Yao
authors.affiliation: Department of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China.
authors.forename: Weihong
authors.initials: W
authors.lastname: Chen
authors.affiliation: Department of Social Medicine and Health Management, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Liang
authors.affiliation: Department of Maternal and Child Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China.
authors.forename: Youjie
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Key Laboratory of Environment and Health, Department of Maternal and Child Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China.
authors.forename: Weimin
authors.initials: W
authors.lastname: Fang
authors.affiliation: Dongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of Medicine, Shiyan, Hubei, Hubei, P.R. China.
authors.forename: Jiang
authors.initials: J
authors.lastname: Zhu
authors.affiliation: Dongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of Medicine, Shiyan, Hubei, Hubei, P.R. China.
authors.forename: Xiulou
authors.initials: X
authors.lastname: Li
authors.affiliation: Dongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of Medicine, Shiyan, Hubei, Hubei, P.R. China.
authors.forename: Handong
authors.initials: H
authors.lastname: Yang
authors.affiliation: Department of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China.
authors.forename: Jing
authors.initials: J
authors.lastname: Yuan
authors.affiliation: Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA, USA.
authors.forename: Frank B
authors.initials: FB
authors.lastname: Hu
authors.affiliation: Professor, Department of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China.
authors.forename: Tangchun
authors.initials: T
authors.lastname: Wu
mesh_terms: D000368:Aged; D001792:Blood Platelets / Q000187:drug effects*; D002681:China; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D019570:Inhalation Exposure / Q000009:adverse effects / Q000032:analysis*; D016015:Logistic Models; D008297:Male; D063847:Mean Platelet Volume; D008875:Middle Aged; D010808:Physical Examination; D011795:Surveys and Questionnaires; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*
chemical_list: D014028:Tobacco Smoke Pollution