title: High-performance thin layer chromatography to assess pharmaceutical product quality.
abstract: OBJECTIVE
  To assess the sustainability, robustness and economic advantages of high-performance thin layer chromatography (HPTLC) for quality control of pharmaceutical products.
  
  
  METHODS
  We compared three laboratories where three lots of cotrimoxazole tablets were assessed using different techniques for quantifying the active ingredient.
  
  
  RESULTS
  The average assay relative standard deviation for the three lots was 1.2 with a range of 0.65-2.0.
  
  
  CONCLUSIONS
  High-performance thin layer chromatography assessments are yielding valid results suitable for assessing product quality. The local pharmaceutical manufacturer had evolved the capacity to produce very high quality products.
authors.affiliation: Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
authors.forename: Eliangiringa
authors.initials: E
authors.lastname: Kaale
authors.affiliation: Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
authors.forename: Vicky
authors.initials: V
authors.lastname: Manyanga
authors.affiliation: Supply Chain Management System, Dar es Salaam, Tanzania.
authors.forename: Narsis
authors.initials: N
authors.lastname: Makori
authors.affiliation: FHI360, Durham, NC, USA.
authors.forename: David
authors.initials: D
authors.lastname: Jenkins
authors.affiliation: United States Agency for International Development, Washington, DC, USA.
authors.forename: Samuel
authors.initials: S
authors.lastname: Michael Hope
authors.affiliation: Supply Chain Management System, Arlington, VA, USA.
authors.forename: Thomas
authors.initials: T
authors.lastname: Layloff
keywords: 
  CCMHP
  ; 
  HPLC
  ; 
  HPTLC
  ; Comparación en la Calidad de Tecnologías del Medicamento; comparaisons des technologies sur la qualité des Médicaments; drug quality technology comparisons