title: [Morphological study of neuroprotective properties of dipeptide mimetic of nerve growth factor (GK-2h) in focal ischemic damage of rat brain prefrontal cortex].
abstract: The neuroprotective effects of dipeptide GK-2h, a mimetic of nerve growth factor, in bifocal photoinduced ischemia in rat brain prefrontal cortex was studied. It was shown that GK-2h, injected intraperitonealy in dose 0.1 mg/kg in 1 h or 4 h after operation and then on 2nd, 4th and 8th days, prevented significantly on 9th day from increasing volume of cortical infarction.
authors.forename: I V
authors.initials: IV
authors.lastname: Barskov
authors.forename: E V
authors.initials: EV
authors.lastname: Stelmashuk
authors.forename: G A
authors.initials: GA
authors.lastname: Romanova
authors.forename: L G
authors.initials: LG
authors.lastname: Khaspekov
mesh_terms: D000818:Animals; D002545:Brain Ischemia / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D009414:Nerve Growth Factors / Q000737:chemistry; D018696:Neuroprotective Agents / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D010455:Peptides / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D017397:Prefrontal Cortex / Q000187:drug effects* / Q000473:pathology; D051381:Rats
chemical_list: D009414:Nerve Growth Factors; D018696:Neuroprotective Agents; D010455:Peptides