title: Clinical factors associated with the diagnosis and progression of diabetic nephropathy.
abstract: As an important complication of diabetic mellitus, diabetic nephropathy (DN) has been the main cause of end-stage renal disease. It is of great importance to diagnose DN early, and to identify the risk factors of disease progression in order to carry out in-time and effective therapies. Previous literatures have reported the role of several clinical factors in the diagnosis and progression of DN, including age, longer diabetes duration, diabetic retinopathy, higher level of hypertension and HbA1c, and so on. However, the significance of these clinical factors is still controversial and limited. This review aimed to evaluate the values and limitations of these factors in diagnosing and predicting the renal outcome of DN.
authors.affiliation: Department of Nephrology, State Key Laboratory of Kidney Diseases, Chinese PLA General Hospital, Beijing, 100853, China.
authors.forename: Shuang
authors.initials: S
authors.lastname: Liang
authors.forename: Qian
authors.initials: Q
authors.lastname: Li
authors.forename: Han-Yu
authors.initials: HY
authors.lastname: Zhu
authors.forename: Jian-Hui
authors.initials: JH
authors.lastname: Zhou
authors.forename: Rui
authors.initials: R
authors.lastname: Ding
authors.forename: Xiang-Mei
authors.initials: XM
authors.lastname: Chen
authors.forename: Guang-Yan
authors.initials: GY
authors.lastname: Cai
mesh_terms: D003928:Diabetic Nephropathies / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D018450:Disease Progression; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000150:complications; D007668:Kidney / Q000503:physiopathology; D014555:Urination Disorders / Q000150:complications
chemical_list: D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human