title: GDSL lipase 1 regulates ethylene signaling and ethylene-associated systemic immunity in Arabidopsis.
abstract: Arabidopsis GDSL lipase 1 (GLIP1) has been shown to modulate systemic immunity through the regulation of ethylene signaling components. Here we demonstrate that the constitutive triple response mutant ctr1-1 requires GLIP1 for the ethylene response, gene expression, and pathogen resistance. The glip1-1 mutant was defective in induced resistance following primary inoculation of necrotrophic pathogens, whereas GLIP1-overexpressing plants showed resistance to multiple pathogens. Necrotrophic infection triggered the downregulation of EIN3 and the activation of ERF1 and SID2 in a GLIP1-dependent manner. These results suggest that GLIP1 positively and negatively regulates ethylene signaling, resulting in an ethylene-associated, necrotroph-induced immune response.
authors.affiliation: Division of Life Sciences, Korea University, Seoul 136-701, Republic of Korea.
authors.forename: Hye Gi
authors.initials: HG
authors.lastname: Kim
authors.affiliation: Division of Life Sciences, Korea University, Seoul 136-701, Republic of Korea.
authors.forename: Sun Jae
authors.initials: SJ
authors.lastname: Kwon
authors.affiliation: Division of Life Sciences, Korea University, Seoul 136-701, Republic of Korea.
authors.forename: Young Jin
authors.initials: YJ
authors.lastname: Jang
authors.affiliation: Environment and Metabolomics Research Team, Korea Basic Science Institute, Seoul 136-701, Republic of Korea.
authors.forename: Joo Hee
authors.initials: JH
authors.lastname: Chung
authors.affiliation: Environment and Metabolomics Research Team, Korea Basic Science Institute, Seoul 136-701, Republic of Korea.
authors.forename: Myung Hee
authors.initials: MH
authors.lastname: Nam
authors.affiliation: Division of Life Sciences, Korea University, Seoul 136-701, Republic of Korea. Electronic address: omkim@korea.ac.kr.
authors.forename: Ohkmae K
authors.initials: OK
authors.lastname: Park
mesh_terms: D017360:Arabidopsis / Q000201:enzymology* / Q000276:immunology / Q000382:microbiology; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D001483:Base Sequence; D002265:Carboxylic Ester Hydrolases / Q000502:physiology*; D004268:DNA-Binding Proteins; D060467:Disease Resistance; D005030:Ethylenes / Q000378:metabolism*; D015870:Gene Expression; D018506:Gene Expression Regulation, Plant / Q000276:immunology; D054884:Host-Pathogen Interactions; D019751:Intramolecular Transferases / Q000378:metabolism; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism; D010454:Peptide Termination Factors / Q000235:genetics / Q000378:metabolism; D010935:Plant Diseases / Q000276:immunology / Q000382:microbiology; D010937:Plant Growth Regulators / Q000378:metabolism; D018515:Plant Leaves / Q000201:enzymology / Q000276:immunology / Q000382:microbiology; D044224:Pseudomonas syringae / Q000502:physiology; D017422:Sequence Analysis, DNA; D015398:Signal Transduction; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism
chemical_list: D029681:Arabidopsis Proteins; D004268:DNA-Binding Proteins; C106987:EIN3 protein, Arabidopsis; D005030:Ethylenes; D009687:Nuclear Proteins; D010454:Peptide Termination Factors; D010937:Plant Growth Regulators; D014157:Transcription Factors; C494978:eukaryotic release factor 1, Arabidopsis; C036216:ethylene; D002265:Carboxylic Ester Hydrolases; C508002:Glip1 protein, Arabidopsis; D019751:Intramolecular Transferases; C058486:isochorismate synthase
keywords: EIN3; ERF1; Ethylene; GLIP1; Salicylic acid; Systemic immunity