title: Ultrasensitive dopamine sensor based on novel molecularly imprinted polypyrrole coated carbon nanotubes.
abstract: A novel electrochemical sensor using the molecularly imprinted (MIP) oxygen-containing polypyrrole (PPy) decorated carbon nanotubes (CNTs) composite was proposed for in vivo detection of dopamine (DA). The prepared sensor exhibits a remarkable sensitivity of (16.18μA/μM) with a linear range of 5.0×10(-11)-5.0×10(-6)M and limit of detection as low as 1.0×10(-11)M in the detection of DA, which might be due to the plenty cavities for binding DA through π-π stacking between aromatic rings and hydrogen bonds between amino groups of DA and oxygen-containing groups of the novel PPy.
authors.affiliation: School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Qian
authors.affiliation: School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
authors.forename: Chenfei
authors.initials: C
authors.lastname: Yu
authors.affiliation: School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
authors.forename: Xi
authors.initials: X
authors.lastname: Zhou
authors.affiliation: School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
authors.forename: Peipei
authors.initials: P
authors.lastname: Ma
authors.affiliation: School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China. Electronic address: shishanwu@nju.edu.cn.
authors.forename: Shishan
authors.initials: S
authors.lastname: Wu
authors.affiliation: School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
authors.forename: Lina
authors.initials: L
authors.lastname: Xu
authors.affiliation: School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China; Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Nanjing 210046, China. Electronic address: shenj57@nju.edu.cn.
authors.forename: Jian
authors.initials: J
authors.lastname: Shen
mesh_terms: D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis*; D003217:Conductometry / Q000295:instrumentation*; D004298:Dopamine / Q000032:analysis* / Q000737:chemistry; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008832:Microchemistry / Q000295:instrumentation*; D054802:Molecular Imprinting / Q000295:instrumentation / Q000379:methods*; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure; D011108:Polymers / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D020099:Coated Materials, Biocompatible; D037742:Nanotubes, Carbon; D011108:Polymers; D011758:Pyrroles; C067635:polypyrrole; D004298:Dopamine
keywords: Carbon nanotubes; Dopamine; Electrochemical sensor; Molecularly imprinted polymers; Polypyrrole