title: Survival after curative surgical treatment for primary oral squamous cell carcinoma.
abstract: The purpose of this retrospective study was to review recurrence rate and survival of patients with primary oral squamous cell carcinoma (OSCC) that have received surgical treatment and adjuvant radio-therapy with curative intent in our clinic over a 6-year period. A total of 106 patients were included. The 5-year overall survival (OS) was 41%, 5-year disease-specific survival (DSS) was 77%, 5-year disease-free survival (DFS) was 72%. DSS was significantly different between early and advanced stage, 87% and 67% respectively (p = 0.04). Recurrence significantly affected survival: OS with or without recurrence at 20 months was 24% and 87% respectively (p < 0.001). Although a guideline based approach for the treatment of OSCC might provide an advantage, more data are needed for these guidelines to be based on.
authors.affiliation: Department of Cranio-Maxillofacial Surgery (Head: Prof. Dr. Dr. P. Kessler), Maastricht University Medical Center MUMC+, P Debbyelaan, Postbus 5800, NL-6202 Maastricht, The Netherlands. Electronic address: m.bloebaum@alumni.maastrichtuniversity.nl.
authors.forename: M
authors.initials: M
authors.lastname: Bloebaum
authors.affiliation: Department of Cranio-Maxillofacial Surgery (Head: Prof. Dr. Dr. P. Kessler), Maastricht University Medical Center MUMC+, P Debbyelaan, Postbus 5800, NL-6202 Maastricht, The Netherlands.
authors.forename: L
authors.initials: L
authors.lastname: Poort
authors.affiliation: Department of Cranio-Maxillofacial Surgery (Head: Prof. Dr. Dr. P. Kessler), Maastricht University Medical Center MUMC+, P Debbyelaan, Postbus 5800, NL-6202 Maastricht, The Netherlands.
authors.forename: R
authors.initials: R
authors.lastname: Böckmann
authors.affiliation: Department of Cranio-Maxillofacial Surgery (Head: Prof. Dr. Dr. P. Kessler), Maastricht University Medical Center MUMC+, P Debbyelaan, Postbus 5800, NL-6202 Maastricht, The Netherlands.
authors.forename: P
authors.initials: P
authors.lastname: Kessler
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D002423:Cause of Death; D059186:Chemoradiotherapy, Adjuvant; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000601:surgery*; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D015996:Survival Rate
chemical_list: D000970:Antineoplastic Agents
keywords: Cancer therapy; Oral squamous cell carcinoma; Survival