title: A first step beyond traditional boundaries: destination therapy with the SynCardia total artificial heart.
abstract: The SynCardia total artificial heart is currently used as a bridge to transplantation therapy in cases of irreversible, acute or chronic, biventricular heart failure. We describe the implementation of this technology in the context of destination therapy in a patient with an end-stage heart failure on grounds of primary amyloidosis.
authors.affiliation: Department of Surgical Therapy of End-stage Heart Failure and Mechanical Circulatory Support, Heart and Vascular Center Duisburg, Duisburg, Germany sotirios.spiliopolos@ejk.de.
authors.forename: Sotirios
authors.initials: S
authors.lastname: Spiliopoulos
authors.affiliation: Department of Surgical Therapy of End-stage Heart Failure and Mechanical Circulatory Support, Heart and Vascular Center Duisburg, Duisburg, Germany.
authors.forename: Reiner
authors.initials: R
authors.lastname: Koerfer
authors.affiliation: Department of Surgical Therapy of End-stage Heart Failure and Mechanical Circulatory Support, Heart and Vascular Center Duisburg, Duisburg, Germany.
authors.forename: Gero
authors.initials: G
authors.lastname: Tenderich
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D009202:Cardiomyopathies / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D006333:Heart Failure / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D006354:Heart, Artificial; D006439:Hemodynamics; D006801:Humans; D000075363:Immunoglobulin Light-chain Amyloidosis; D008297:Male; D011474:Prosthesis Design; D013997:Time Factors; D016896:Treatment Outcome; D016276:Ventricular Function
keywords: Amyloidosis; Artificial heart; Cardiac failure