title: [A Cochrane meta-analysis regarding procalcitonin is in accordance with international goals for the use of antibiotics].
abstract: Antimicrobial resistance towards antibiotics is an increasing issue for the international society. A Cochrane meta-analysis regarding procalcitonin (PCT) as guidance for initiating and discontinuation of antibiotic treatment in respiratory tract infections in a total of 4,221 patients in various care settings has shown promising results for guiding treatment with a PCT cut-off of 0.25 ng/ml, although more research is needed to clarify possible risks to the approach, especially in intensive care units.
authors.affiliation: Medicinsk Afdeling O, Herlev Hospital Kildebakken 43, 2. th., 2860 Søborg. peterberg@dadlnet.dk
authors.forename: Peter Løvgreen
authors.initials: PL
authors.lastname: Berg
authors.forename: Bjarne Orskov
authors.initials: BO
authors.lastname: Lindhardt
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy; D015415:Biomarkers / Q000097:blood; D002116:Calcitonin / Q000097:blood*; D015740:Calcitonin Gene-Related Peptide; D004363:Drug Utilization; D006801:Humans; D011498:Protein Precursors / Q000097:blood*; D012141:Respiratory Tract Infections / Q000188:drug therapy; D012196:Review Literature as Topic
chemical_list: D000900:Anti-Bacterial Agents; D015415:Biomarkers; C000606589:CALCA protein, human; D011498:Protein Precursors; D002116:Calcitonin; D015740:Calcitonin Gene-Related Peptide