title: Study of hydatidosis-attributed mortality in endemic area.
abstract: BACKGROUND
  Cystic hydatid disease is still an important health problem in European Mediterranean areas. In spite of being traditionally considered as a "benign" pathology, cystic echinococcosis is an important cause of morbidity in these areas. Nevertheless, there are few analyses of mortality attributed to human hydatidosis.
  
  
  OBJECTIVE
  To describe the epidemiology, the mortality rate and the causes of mortality due to E. granulosus infection in an endemic area.
  
  
  METHODS
  A retrospective study followed up over a period of 14 years (1998-2011).
  
  
  RESULTS
  Of the 567 patients diagnosed with hydatid disease over the period 1998-2011, eleven deaths directly related to hydatid disease complications were recorded. Ten patients (90.9%) died due to infectious complications and the remaining one (9.1%) died due to mechanical complications after a massive hemoptysis. We registered a case fatality rate of 1.94% and a mortality rate of 3.1 per 100.000 inhabitants.
  
  
  CONCLUSIONS
  Hydatidosis is still a frequent parasitic disease that causes a considerable mortality. The main causes of mortality in patients with hydatidosis are complications related to the rupture of CE cysts with supurative collangitis. Therefore, an expectant management can be dangerous and it must be only employed in well-selected patients.
authors.affiliation: Seccion de Enfermedades Infecciosas, Servicio de Medicina Interna, Complejo Asistencial Universitario de Salamanca, CIETUS, IBSAL, Salamanca, Spain.
authors.forename: Moncef
authors.initials: M
authors.lastname: Belhassen-García
authors.affiliation: Servicio de Medicina Interna, Complejo Asistencial Universitario de Salamanca, IBSAL, Salamanca, Spain.
authors.forename: Angela
authors.initials: A
authors.lastname: Romero-Alegria
authors.affiliation: Servicio de Medicina Interna, Complejo Asistencial Universitario de Salamanca, CIETUS, IBSAL, Salamanca, Spain.
authors.forename: Virginia
authors.initials: V
authors.lastname: Velasco-Tirado
authors.affiliation: Departmento de Medicina Preventiva, Salud Publica y Microbiologia Medica, Universidad de Salamanca, Salamanca, Spain.
authors.forename: Montserrat
authors.initials: M
authors.lastname: Alonso-Sardón
authors.affiliation: Servicio de Medicina Interna, Complejo Asistencial Universitario de Salamanca, IBSAL, Salamanca, Spain.
authors.forename: Amparo
authors.initials: A
authors.lastname: Lopez-Bernus
authors.affiliation: Servicio de Medicina Interna, Complejo Asistencial Universitario de Salamanca, CIETUS, IBSAL, Salamanca, Spain.
authors.forename: Lucia
authors.initials: L
authors.lastname: Alvela-Suarez
authors.affiliation: CIETUS, IBSAL, Universidad de Salamanca, Salamanca, Spain.
authors.forename: Luis Perez
authors.initials: LP
authors.lastname: del Villar
authors.affiliation: Servicio de Medicina Interna, Complejo Asistencial Universitario de Salamanca, IBSAL, Salamanca, Spain.
authors.forename: Adela
authors.initials: A
authors.lastname: Carpio-Perez
authors.affiliation: CAP Camargo, José Barros, Cantabria, Spain.
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Galindo-Perez
authors.affiliation: Seccion de Enfermedades Infecciosas, Servicio de Medicina Interna, Complejo Asistencial Universitario de Salamanca, CIETUS, IBSAL, Salamanca, Spain.
authors.forename: Miguel
authors.initials: M
authors.lastname: Cordero-Sanchez
authors.affiliation: Servicio de Medicina Interna, Hospital General de Palencia "Río Carrión", Palencia, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Pardo-Lledias
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D002423:Cause of Death; D004443:Echinococcosis / Q000453:epidemiology* / Q000401:mortality; D048209:Echinococcus granulosus; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D016017:Odds Ratio; D012189:Retrospective Studies; D013030:Spain