title: Fournier's gangrene caused by Actinomyces funkei, Fusobacterium gonidiaformans and Clostridium hathewayi.
abstract: We report the first case of Fournier's gangrene caused by three unusual anaerobic organisms: Actinomyces funkei, Fusobacterium gonidiaformans and Clostridium hathewayi. The infection occurred in a 73-year-old man without typical risk factors for the development of Fournier's gangrene. Clinical outcome was good after prolonged antibiotic treatment and extensive debridement of the perineum. The case suggests that A. funkei, F. gonidiaformans and C. hathewayi should be considered as potential pathogens of Fournier's gangrene. Human infections caused by these organisms are very rare but can be underestimated because correct identification is very difficult, especially in polymicrobial infections such as Fournier's gangrene.
authors.affiliation: Sección de Microbiología, Hospital Universitario de Guadalajara, Guadalajara, Spain. Electronic address: danielt@sescam.jccm.es.
authors.forename: Daniel
authors.initials: D
authors.lastname: Tena
authors.affiliation: Sección de Microbiología, Hospital Universitario de Guadalajara, Guadalajara, Spain.
authors.forename: Cristina
authors.initials: C
authors.lastname: Losa
authors.affiliation: Servicio de Bacteriología, Centro Nacional de Microbiología, Majadahonda, Spain.
authors.forename: María José
authors.initials: MJ
authors.lastname: Medina-Pascual
authors.affiliation: Servicio de Bacteriología, Centro Nacional de Microbiología, Majadahonda, Spain.
authors.forename: Juan Antonio
authors.initials: JA
authors.lastname: Sáez-Nieto
mesh_terms: D000190:Actinomyces / Q000302:isolation & purification*; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology* / Q000628:therapy; D003013:Clostridium / Q000302:isolation & purification*; D003646:Debridement; D018934:Fournier Gangrene / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology* / Q000628:therapy; D005673:Fusobacterium / Q000302:isolation & purification*; D006801:Humans; D008297:Male
chemical_list: D000900:Anti-Bacterial Agents
keywords: Actinomyces funkei; Anaerobic infection; Clostridium hathewayi; Fournier's gangrene; Fusobacterium gonidiaformans; Polymicrobial infection