title: Rosai-Dorfman disease with exclusive intra-abdominal lymphadenopathy masquerading as Wilkie's syndrome.
abstract: Rosai-Dorfman disease is a rare histiocytic proliferative disorder with a distinctive microscopic appearance. Patients usually present with nonspecific symptoms and massive cervical lymphadenopathy. Exclusive involvement of intra-abdominal lymph nodes is unusual and presentation mimicking Wilkie's syndrome due to compression of the third part of the duodenum by enlarged retroduodenal lymph nodes is rare. This entity should be included in the differential diagnosis with infectious, granulomatous and malignant causes of intra-abdominal lymphadenopathy. We highlight an uncommon presentation and discuss the challenges in the diagnosis and management of Rosai-Dorfman disease.
authors.affiliation: Department of Surgical Gastroenterology, King George's Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Tarique
authors.initials: T
authors.lastname: Hussain Ashraf
authors.affiliation: Department of Surgical Gastroenterology, King George's Medical University, Lucknow, Uttar Pradesh, India. Electronic address: tarique536@yahoo.co.in.
authors.forename: Abhijit
authors.initials: A
authors.lastname: Chandra
authors.affiliation: Department of Surgery, SN Medical College, Agra, Uttar Pradesh, India.
authors.forename: Ramendra K
authors.initials: RK
authors.lastname: Jauhari
authors.affiliation: Department of Surgical Gastroenterology, King George's Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Sunil
authors.initials: S
authors.lastname: Kumar Singh
authors.affiliation: Department of Surgical Gastroenterology, King George's Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: M
authors.initials: M
authors.lastname: Noushif
mesh_terms: D034841:Abdominal Cavity; D003937:Diagnosis, Differential; D004378:Duodenal Diseases / Q000209:etiology*; D017809:Fatal Outcome; D015618:Histiocytosis, Sinus / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D013478:Superior Mesenteric Artery Syndrome / Q000175:diagnosis*
keywords: Histiocytosis; Lymphadenopathy; Rosai–Dorfman disease; Wilkie’s syndrome