title: Esomeprazole: a safe alternative to lansoprazole allergy?
abstract: Proton pump inhibitors (PPIs) are widely prescribed drugs in daily practice. Allergic reactions, even small number of anaphylactic reactions to PPIs have been reported. Omeprazole, lansoprazole, pantoprazole, rapeprazol and esomeprazole are classified in the same group. Despite the similarity of biochemical structures among these drugs, presence of cross-reactivity between PPIs is controversial.1,2 In this letter, we present 3 lansoprazole allergy cases, who were prescribed and took esomeprazole safely after allergic reactions to lansoprazole.
authors.affiliation: Department of Gastroenterology, Gata Haydarpasa Training Hospital, 34668 Uskudar-Istanbul, Turkey. drmuammerkara70@hotmail.com.
authors.forename: Muammer
authors.initials: M
authors.lastname: Kara
authors.affiliation: Department of Gastroenterology, Gata Haydarpasa Training Hospital, 34668 Uskudar-Istanbul, Turkey. alpaslantanoglu@yahoo.com.
authors.forename: Alpaslan
authors.initials: A
authors.lastname: Tanoglu
authors.affiliation: Department of Immunulogy and Allergy, Gata Haydarpasa Training Hospital, 34668 Uskudar-Istanbul, Turkey. kotiloglu@hotmail.com.
authors.forename: Ali
authors.initials: A
authors.lastname: Kutlu
authors.affiliation: Department of Internal Medicine, Gata Haydarpasa Training Hospital, 34668 Uskudar-Istanbul, Turkey. ozgursirkeci@hotmail.com.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Sirkeci
authors.affiliation: Department of Gastroenterology, Hitit University, Corum Training and Research Hospital, Çorum, Turkey. drkekilli@gmail.com.
authors.forename: Murat
authors.initials: M
authors.lastname: Kekilli
mesh_terms: D000328:Adult; D004342:Drug Hypersensitivity; D064098:Esomeprazole / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D064747:Lansoprazole / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D054328:Proton Pump Inhibitors / Q000009:adverse effects*; D012882:Skin Tests
chemical_list: D054328:Proton Pump Inhibitors; D064747:Lansoprazole; D064098:Esomeprazole