title: Cervical sympathetic chain paraganglioma: a report of 2 cases and a literature review.
abstract: We review 2 cases of surgically and pathologically confirmed paraganglioma of the cervical sympathetic chain. Both patients-a 46-year-old man and a 33-year-old woman-were treated surgically. Intraoperatively, both tumors were found to be hypervascular and arising from the cervical sympathetic chain. Histopathologic analysis confirmed both as paragangliomas. Paragangliomas arising from the cervical sympathetic chain are exceptionally rare, but they must be considered in the differential diagnosis of parapharyngeal masses. They often present with ipsilateral Horner syndrome and oropharyngeal fullness, and they may be associated with a higher rate of catecholamine secretion. Typical imaging characteristics include anterolateral or lateral displacement of both the carotid and jugular vessels.
authors.affiliation: Head and Neck Institute, Desk A71, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.
authors.forename: Rahul
authors.initials: R
authors.lastname: Seth
authors.forename: Manzoor
authors.initials: M
authors.lastname: Ahmed
authors.forename: Aaron P
authors.initials: AP
authors.lastname: Hoschar
authors.forename: Benjamin G
authors.initials: BG
authors.lastname: Wood
authors.forename: Joseph
authors.initials: J
authors.lastname: Scharpf
mesh_terms: D000328:Adult; D005260:Female; D006732:Horner Syndrome / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010236:Paraganglioma, Extra-Adrenal / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D010524:Peripheral Nervous System Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D013564:Sympathetic Nervous System / Q000473:pathology* / Q000601:surgery