title: Postoperative cognitive dysfunction in living liver transplant donors.
abstract: OBJECTIVE
  Postoperative cognitive dysfunction is a serious complication that may be associated with increased mortality. Living-donor liver transplant includes major surgery for the donor. The purpose of this study was to evaluate preoperative and postoperative cognitive function of liver donors in living-donor liver transplant.
  
  
  METHODS
  In 102 patients who had hepatectomy for liver transplant donation, preoperative and postoperative (1 week) neuropsychologic tests were performed including the Trail Making Test, the Stroop effect, score on the Beck Depression Inventory, and the mini-mental state examination.
  
  
  RESULTS
  Liver transplant donors had significantly lower mean Trail Making A Test duration and greater mean Trail Making B Test error number after than before surgery. The mean Stroop effect reading durations (black and white reading; reading colored words) were significantly greater after than before surgery; the mean time difference between naming the colors of colored words minus reading colored words, and the error number, were smaller after than before surgery. The mean score on the Beck Depression Inventory and mini-mental state examination score were similar before and after surgery.
  
  
  CONCLUSIONS
  Mild frontal lobe dysfunction may be present in liver donors at 1 week after surgery, and postoperative attention problems may be experienced by these patients.
authors.affiliation: Department of Anesthesiology and Reanimation, Inonu University, Faculty of Medicine, Malatya, Turkey.
authors.forename: Nizamettin
authors.initials: N
authors.lastname: Bucak
authors.forename: Zekine
authors.initials: Z
authors.lastname: Begeç
authors.forename: Feray
authors.initials: F
authors.lastname: Erdil
authors.forename: Hüseyin İlksen
authors.initials: Hİ
authors.lastname: Toprak
authors.forename: Birgül Elbozan
authors.initials: BE
authors.lastname: Cumurcu
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Demirtaş
authors.forename: Saim
authors.initials: S
authors.lastname: Yoloğlu
authors.forename: Mahmut
authors.initials: M
authors.lastname: Durmuş
authors.forename: Mehmet Özcan
authors.initials: MÖ
authors.lastname: Ersoy
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001288:Attention; D003071:Cognition; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology / Q000523:psychology; D005260:Female; D005625:Frontal Lobe / Q000503:physiopathology; D006498:Hepatectomy / Q000009:adverse effects*; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects*; D019520:Living Donors / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D057190:Stroop Test; D013997:Time Factors; D014145:Trail Making Test; D016896:Treatment Outcome; D055815:Young Adult