title: Papillon Lefevre Syndrome and footsteps of mycobacterium tuberculosis.
abstract: Papillon Lefevre Syndrome ( PLS ) is a very rare genetic syndrome that only less than 500 cases have reported in the world. Patients have a typical cutaneous involvement with hyperkeratosis especially on the soles and palms and early shedding of primary teeth. Internal organs involvement such as liver abscess has been presented as case reports. This is for the first time that a genetically documented PLS with footsteps of mycobacterium tuberculosis in liver and kidney will report.
authors.affiliation: Department of Asthma, Allergy and Immunology, Bahrami Children Hospital, Tehran University of Medical Sciences, Tehran, Iran. f_zandieh2000@yahoo.com.
authors.forename: Fariborz
authors.initials: F
authors.lastname: Zandieh
authors.affiliation: Department of Asthma, Allergy and Immunology, Bahrami Children Hospital, Tehran University of Medical Sciences, Tehran, Iran. f_zandieh2000@yahoo.com.
authors.forename: Bahram
authors.initials: B
authors.lastname: Mirsaed Ghazi
authors.affiliation: Department of Infectiousn Diseases, Bahrami Children Hospital, Tehran University of Medical Sciences, Tehran, Iran. f_zandieh2000@yahoo.com.
authors.forename: Anahita
authors.initials: A
authors.lastname: Izadi
authors.affiliation: Department of Infectiousn Diseases, Children Medical Center, Tehran University of Medical Sciences, Tehran, Iran. f_zandieh2000@yahoo.com.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Gharegozlu
authors.affiliation: Department of Asthma, Allergy and Immunology, Bahrami Children Hospital, Tehran University of Medical Sciences, Tehran, Iran. f_zandieh2000@yahoo.com.
authors.forename: Motahareh
authors.initials: M
authors.lastname: Aghajani
authors.affiliation: Department of Asthma, Allergy and Immunology, Bahrami Children Hospital, Tehran University of Medical Sciences, Tehran, Iran. f_zandieh2000@yahoo.com.
authors.forename: Mahdi
authors.initials: M
authors.lastname: Sheikh
mesh_terms: D000293:Adolescent; D005533:Foot Dermatoses / Q000209:etiology*; D006801:Humans; D008297:Male; D010214:Papillon-Lefevre Disease / Q000150:complications* / Q000188:drug therapy; D012176:Retinoids / Q000627:therapeutic use; D014376:Tuberculosis / Q000209:etiology*
chemical_list: D012176:Retinoids