title: Orofacial dermal fillers: foreign body reactions, histopathologic features, and spectrometric studies.
abstract: OBJECTIVE
  The aim of this study is to assess the different histopathologic presentations of dermal filler materials-induced foreign body reactions by spectrometric analyses.
  
  
  METHODS
  Sixteen cases of dermal filler foreign body reactions in the orofacial region were retrieved from the 2006-2013 period. The histologic features were evaluated and categorized into 5 groups (I to V). Unstained deparaffinized sections of representative tissue from one case in each of groups I to IV were sent for spectrometric analysis, along with samples of 2 popular dermal fillers (Juvéderm and Radiesse).
  
  
  RESULTS
  With the help of spectrometric analysis, we were able to correlate the histopathologic presentations with the specific type of dermal filler used.
authors.affiliation: Resident, Oral and Maxillofacial Pathology, Department of Diagnostic Sciences, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA, USA. Electronic address: owoshoaa@upmc.edu.
authors.forename: Adepitan A
authors.initials: AA
authors.lastname: Owosho
authors.affiliation: Assistant Professor, Department of Diagnostic Sciences, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA, USA.
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Bilodeau
authors.affiliation: Assistant Professor, Department of Pathology, Division of Dermatopathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
authors.forename: John
authors.initials: J
authors.lastname: Vu
authors.affiliation: Associate Professor, Department of Diagnostic Sciences, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA, USA.
authors.forename: Kurt F
authors.initials: KF
authors.lastname: Summersgill
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001672:Biocompatible Materials / Q000009:adverse effects*; D003094:Collagen / Q000009:adverse effects*; D003357:Cosmetic Techniques / Q000009:adverse effects*; D005260:Female; D005549:Foreign-Body Reaction / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010784:Photomicrography; D011108:Polymers / Q000009:adverse effects*; D013055:Spectrophotometry, Infrared
chemical_list: D001672:Biocompatible Materials; D011108:Polymers; D003094:Collagen