title: Asymmetric semipinacol rearrangement of 2,3-allenols with N-bromo-1,8-naphthalimide.
abstract: A method using quinidine and optically active binol-derived phosphoric acid as a cocatalyst to catalyze the asymmetric semipinacol rearrangement of 2,3-allenols forming optically active 3-bromo-3-enals that contain an all-carbon quaternary stereocenter has been developed. After some further treatments, the products with practical enantiomeric purity could be prepared.
authors.affiliation: Laboratory of Molecular Recognition and Synthesis, Department of Chemistry, Zhejiang University, Hangzhou, 310027, Zhejiang, P. R. China. masm@sioc.ac.cn.
authors.forename: Binjie
authors.initials: B
authors.lastname: Guo
authors.forename: Chunling
authors.initials: C
authors.lastname: Fu
authors.forename: Shengming
authors.initials: S
authors.lastname: Ma