title: [Reemergence of measles. Epidemic situation in the Valencian Community during the years 2011 and 2012].
abstract: Measles incidence declined until becomes a sporadic reporting and infrequent notification in the last decade. The reemergence of the disease reached 744 cases in 2012, a rate of 14.50×10(5) inhabitants. A classic design in Public Health Surveillance was performed: retrospective analysis of cumulative incidence and characteristics of the affected subjects. Those dates were in record linkage with Valencia Microbiology Network (RedMIVA). Finally, 976 cases of measles were confirmed in 2011-2012 epidemic period. Time-line distribution shows three waves with amplitude length on 12-15 weeks. Proportion of unvaccinated or unknown subjects came up to 85% of cases. 25 outbreaks were reported, 499 cases associated. In 7 of the 10 community outbreaks early cases were from Roma population unvaccinated. In the city of Valencia was applied post-exposure prophylaxis in 32 schools and was observed low coverage: between 63% and 77% in 8 schools and less than 50% in 4. Serum negative rate was 12.4% and we highlight the rate under 16 months: 44.8%. Cohorts of 20-59 years had negative rates between 13.5 to 5.9%. The origin of the epidemic was the importation of cases to a territory with inadequate immune protection against measles. Its impact and development was conditioned by previous immunization coverage, the social and ethnic pattern of different areas or quarters and the extensive application of post-exposure prophylaxis at school and family contacts of cases.
authors.affiliation: Dirección General de Salud Pública de la Comunidad Valenciana, Servicio de Vigilancia y Control Epidemiológico. Electronic address: guiral_sil@gva.es.
authors.forename: Silvia Guiral
authors.initials: SG
authors.lastname: Rodrigo
authors.affiliation: Sección de Epidemiología, Centro de Salud Pública de Valencia, Valencia, España.
authors.forename: Rosana Guaita
authors.initials: RG
authors.lastname: Calatrava
authors.affiliation: Sección de Epidemiología de Alicante, Alicante, España.
authors.forename: M
authors.initials: M
authors.lastname: Vicenta Rigo Medrano
authors.affiliation: Unidad de Epidemiología de Elx, Elx, Alicante, España.
authors.forename: Miquel Amat
authors.initials: MA
authors.lastname: Vidal
authors.affiliation: Dirección General de Salud Pública de la Comunidad Valenciana, Servicio de Vigilancia y Control Epidemiológico.
authors.forename: Miguel
authors.initials: M
authors.lastname: Martín-Sierra Balibrea
authors.affiliation: Dirección General de Salud Pública de la Comunidad Valenciana, Servicio de Vigilancia y Control Epidemiológico.
authors.forename: Isabel Huertas
authors.initials: IH
authors.lastname: Zarco
authors.affiliation: Sección de Epidemiología de Alicante, Alicante, España.
authors.forename: Jorge Roda
authors.initials: JR
authors.lastname: Ramón
authors.affiliation: Sección de Epidemiología, Centro de Salud Pública de Valencia, Valencia, España.
authors.forename: Antonio Salazar
authors.initials: AS
authors.lastname: Cifre
authors.affiliation: Dirección General de Salud Pública de la Comunidad Valenciana, Servicio de Vigilancia y Control Epidemiológico.
authors.forename: Francisco González
authors.initials: FG
authors.lastname: Morán
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008457:Measles / Q000453:epidemiology*; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology; D013997:Time Factors; D055815:Young Adult
keywords: Brote de sarampión; Epidemia; Epidemics; Intervención y control; Intervention and control; Measles; Measles outbreak; Sarampión; Surveillance; Vaccination; Vacunación; Vigilancia