title: Seizure duration determined by subdural electrode recordings in adult patients with intractable focal epilepsy.
abstract: OBJECTIVE
  To investigate the duration of seizures and its relationship to seizure type, epilepsy syndrome, and seizure clustering.
  
  
  METHODS
  We examined 1,251 seizures from 152 patients who underwent video-electrocorticographic monitoring with subdural electrodes. Their seizure duration, seizure types, epilepsy syndromes, and seizure clusters were analyzed.
  
  
  RESULTS
  The median seizure duration was 91.5s (4-1016s). There were 34 (2.7%) seizures lasting > 5 minutes in 20 (13.2%) patients. There was a significant difference in seizure duration according to seizure types (p < 0.0001), but not to epilepsy syndromes. There were 99 seizure clusters in 67 (44.1%) patients. The first seizure in a cluster of seizures tended to last longer than non-cluster seizures (median 98s versus 89s, p = 0.033). Seizure duration was significantly longer in mesial temporal lobe epilepsy than in neocortical lobe epilepsy (median 103s versus 87s, p = 0.041). Rate of seizure cluster was lower in mTLE (38.0%) than in NLE (47.1%), but this difference was not significant.
  
  
  CONCLUSIONS
  Seizure durations were different among seizure types. Seizure clustering also differ between patients with mTLE and those with NLE, which suggests different seizure generation and propagation among different epileptogenic foci. This study has implications for the identification of abnormally prolonged seizures.
authors.affiliation: Departments of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine;
authors.forename: Daeyoung
authors.initials: D
authors.lastname: Kim
authors.affiliation: Department of Neurology, Pusan National University Yangsan Hospital, School of Medicine;
authors.forename: Jae-Wook
authors.initials: JW
authors.lastname: Cho
authors.affiliation: Department of Neurology, Kosin University College of Medicine, Seoul, Korea.
authors.forename: Jihyun
authors.initials: J
authors.lastname: Lee
authors.affiliation: Departments of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine;
authors.forename: Eun Yeon
authors.initials: EY
authors.lastname: Joo
authors.affiliation: Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine;
authors.forename: Seung Chyul
authors.initials: SC
authors.lastname: Hong
authors.affiliation: Departments of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine;
authors.forename: Seung Bong
authors.initials: SB
authors.lastname: Hong
authors.affiliation: Departments of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine;
authors.forename: Dae-Won
authors.initials: DW
authors.lastname: Seo
keywords: Epilepsy; Seizure cluster; Seizure duration; Subdural grid