title: [Deitiforine, an antiinfluenza chemotherapeutic].
abstract: The problem of prophylaxis and therapy of influenza infections remains one of the priority goals for medical science and practical health care. The review includes the discussion of antiviral activity of Deitiforine, a Russian chemotherapeutic. The data on the toxicity and the specific activity spectrum in cell cultures, chicken embryos and laboratory animals are presented. The problem of the influenza viruses resistance to cage compounds and in particular to rimantadine and Deitiforine is also discussed.
authors.forename: S N
authors.initials: SN
authors.lastname: Tandura
authors.forename: V V
authors.initials: VV
authors.lastname: Zarubaev
authors.forename: P M
authors.initials: PM
authors.lastname: Anfimov
authors.forename: O I
authors.initials: OI
authors.lastname: Kiselev
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D018929:Cell Culture Techniques; D002642:Chick Embryo; D024882:Drug Resistance, Viral / Q000187:drug effects*; D006801:Humans; D009980:Influenza A virus; D007251:Influenza, Human / Q000188:drug therapy*; D009930:Organic Chemicals / Q000494:pharmacology
chemical_list: D000998:Antiviral Agents; D009930:Organic Chemicals; C060204:deitiforin