title: Transformations of X (C, O, N)-CN Bonds: Cases of Selective X (C, O, N)-C Activation.
abstract: Activation of C-C, C-N, and C-O bonds has in recent decades been recognized as a valuable strategic objective. While considerable progress has been achieved, many of the more challenging issues,e.g., regioselective activation of specific C-X (C, O, N) bonds, chemoselective cleavage of C(sp3)-X bonds, enantioselective activation and even the successful application of solid catalysts in such transformations remain elusive. The research disclosed herein summarize recent advances in C-X bond cleavages, including regioselective processes, although the carbon is activated in the form of a cyano group.
authors.affiliation: Division of chemistry, Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9038 (USA).
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
authors.affiliation: Division of chemistry, Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9038 (USA).
authors.forename: John Russell
authors.initials: JR
authors.lastname: Falck
keywords: C-CN bond; N-CN bond; O-CN bond; cyanation; silicon reagent