title: UK Renal Registry 16th annual report: chapter 9 adequacy of haemodialysis in UK adult patients in 2012: national and centre-specific analyses.
abstract: BACKGROUND
  Outcomes in patients treated with haemodialysis (HD) are influenced by the delivered dose of dialysis. The UK Renal Association (RA) publishes clinical practice guidelines which include recommendations for dialysis dose. The urea reduction ratio (URR) is a widely used measure of dialysis dose and has historically been the measure of adequacy reported by the UKRR. This chapter aims to determine the extent to which patients achieved the recommended UK target.
  
  
  METHODS
  All 71 UK renal centres submitted data to the UK Renal Registry (UKRR). Two groups of patients were included in the analyses: the prevalent HD patient population on 30st September 2012 and the incident HD patient population for 2011. Centres returning data on <50% of their patient population or centres with <20 patients were excluded from centrespecific comparisons.
  
  
  RESULTS
  Data regarding URR were available from 63 renal centres in the UK. Forty nine centres provided URR data on more than 90% of prevalent HD patients. The proportion of patients in the UK who met the UK clinical practice guideline for URR (>65%) increased from 69% in 2000 to 88% in 2012. There was persistent variation observed between centres, with 21 centres attaining the RA clinical practice guideline in >90% of patients, 38 centres attaining the guideline in 70-90% of patients and one centre in less than 70% of patients. The overall proportion of prevalent HD patients with a URR >65% has continued to improve over time.
  
  
  CONCLUSIONS
  The delivered dose of HD, as measured by URR for patients with established renal failure, has increased over the last decade. Whilst the majority of UK patients achieved the target URR there was considerable variation between centres in the percentage of patients achieving the current guideline.
authors.affiliation: UK Renal Registry, Bristol, UK.
authors.forename: Catriona
authors.initials: C
authors.lastname: Shaw
authors.forename: Retha
authors.initials: R
authors.lastname: Steenkamp
authors.forename: Andrew
authors.initials: A
authors.lastname: Davenport
mesh_terms: D000328:Adult; D000847:Annual Reports as Topic; D002391:Catchment Area, Health / Q000706:statistics & numerical data; D005260:Female; D019983:Guideline Adherence / Q000639:trends; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008297:Male; D017410:Practice Guidelines as Topic; D012042:Registries / Q000706:statistics & numerical data*; D006435:Renal Dialysis / Q000592:standards* / Q000639:trends; D016896:Treatment Outcome; D006113:United Kingdom; D014508:Urea / Q000097:blood*
chemical_list: D014508:Urea