title: Carbon-carbon bond activation with 8-acylquinolines.
abstract: Synthetically relevant advances in the area of carbon-carbon sigma bond activation have been made possible by 8-acylquinoline directing groups. Stable rhodium metallacycle intermediates have been shown to undergo a variety of transformations, including carboacylation reactions, to produce value-added products containing all-carbon quaternary centers. The kinetic profile of such reactions has been shown to be substrate dependent.
authors.affiliation: Department of Chemistry, University of Minnesota, 207 Pleasant St. SE, Minneapolis, MN, 55455, USA.
authors.forename: Ashley M
authors.initials: AM
authors.lastname: Dreis
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Douglas