title: [Peptide geroprotector application for treatment of elderly and senile patients with prostatic hyperplasia].
abstract: The blind randomized placebo-controlled study of the efficacy of bladder peptide bioregulator Chitomur for the treatment of older age groups of men with benign prostatic hyperplasia was conducted. The effect of the drug on the main urodynamic parameters, symptoms dynamic of the lower urinary tract function disturbances, prostate volume and the quality of life of men with benign prostatic hyperplasia in age from 62 to 83 years was evaluated. It was found that the course application of peptide bioregulator Chitomur in elderly and senile patients with benign prostatic hyperplasia significantly improves the basic parameters of urination. That was accompanied by improved quality of life of the patients. The achieved improvement of urodynamic parameters and quality of life does not reduce during the month following the end of treatment. No adverse effects of the drug were found during the study, which is important for elderly patients and distinguishes it from the conventional drugs used for the treatment of patients with benign prostatic hyperplasia.
authors.forename: V G
authors.initials: VG
authors.lastname: Gomberg
authors.forename: V G
authors.initials: VG
authors.lastname: Ryzhak
authors.forename: R V
authors.initials: RV
authors.lastname: Liutov
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004305:Dose-Response Relationship, Drug; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010455:Peptides / Q000008:administration & dosage*; D011470:Prostatic Hyperplasia / Q000188:drug therapy* / Q000503:physiopathology; D016896:Treatment Outcome; D001743:Urinary Bladder / Q000187:drug effects / Q000503:physiopathology; D014563:Urodynamics / Q000187:drug effects*
chemical_list: D010455:Peptides; C069549:prostatilen