title: Reference range of fetal transverse cerebellar diameter between 18 and 24 weeks of pregnancy in a Brazilian population.
abstract: To determine a reference range of fetal transverse cerebellar diameter in Brazilian population. This was a retrospective cross-sectional study with 3772 normal singleton pregnancies between 18 and 24 weeks of pregnancy. The transverse cerebellar diameter was measured on the axial plane of the fetal head at the level of the lateral ventricles, including the thalamus, cavum septum pellucidum, and third ventricle. To assess the correlation between transverse cerebellar diameter and gestational age, polynomial equations were calculated, with adjustments by the determination coefficient (R2). The mean of fetal transverse cerebellar diameter ranged from 18.49 ± 1.24 mm at 18 weeks to 25.86 ± 1.66 mm at 24 weeks of pregnancy. We observed a good correlation between transverse cerebellar diameter and gestational age, which was best represented by a linear equation: transverse cerebellar diameter: -6.21 + 1.307*gestational age (R2 = 0.707). We determined a reference range of fetal transverse cerebellar diameter for the second trimester of pregnancy in Brazilian population.
authors.affiliation: Referral Center for Teaching of Diagnostic Imaging, São Paulo-SP, Brazil Department of Obstetrics, Paulista School of Medicine, São Paulo Federal University, São Paulo-SP, Brazil araujojred@terra.com.br.
authors.forename: Edward
authors.initials: E
authors.lastname: Araujo Júnior
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine of Ribeirão Preto-São Paulo University, Ribeirão Preto-SP, Brazil Ultrasonography and Retraining Medical School of Ribeirão Preto, Ribeirão Preto-SP, Brazil.
authors.forename: Wellington P
authors.initials: WP
authors.lastname: Martins
authors.affiliation: Department of Obstetrics, Paulista School of Medicine, São Paulo Federal University, São Paulo-SP, Brazil.
authors.forename: Luciano Marcondes Machado
authors.initials: LM
authors.lastname: Nardozza
authors.affiliation: Referral Center for Teaching of Diagnostic Imaging, São Paulo-SP, Brazil.
authors.forename: Claudio Rodrigues
authors.initials: CR
authors.lastname: Pires
authors.affiliation: Referral Center for Teaching of Diagnostic Imaging, São Paulo-SP, Brazil.
authors.forename: Sebastião Marques Zanforlin
authors.initials: SM
authors.lastname: Filho
mesh_terms: D001938:Brazil; D002531:Cerebellum / Q000000981:diagnostic imaging* / Q000196:embryology*; D003430:Cross-Sectional Studies; D005260:Female; D005333:Fetus / Q000033:anatomy & histology*; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D012016:Reference Values; D012189:Retrospective Studies; D016216:Ultrasonography, Prenatal
keywords: Brazilian population; fetus; reference range; transverse cerebellar diameter