title: Benefits of the povidone-iodine: simultaneously decrease risk of infection and tumor seeding after percutaneous endoscopic gastrostomy.
abstract: Percutaneous endoscopic gastrostomy (PEG) is a well-established enteral feeding modality in patients with oropharyngeal/esophageal cancer; however, these patients are at risk for two possible PEG-related complications. First, oropharyngeal organisms may be transported to the PEG stoma and thus increase the risk of peristomal infection. Second, oropharyngeal/esophageal cancer cells may adhere to the PEG tube and thus increase the risk of tumor seeding along the PEG tract. Because of its microbicidal and tumoricidal effects, povidone-iodine pretreatment of the PEG tube may decrease the risk of peristomal infection and tumor seeding associated with PEG insertion in patients with oropharyngeal/esophageal cancer. To test this hypothesis, we brushed povidone-iodine onto the outer surface of PEG tubes prior to insertion.
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taiwan.
authors.forename: Wei-Kuo
authors.initials: WK
authors.lastname: Chang
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taiwan.
authors.forename: Hsuan-Hwai
authors.initials: HH
authors.lastname: Lin
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taiwan.
authors.forename: Tsai-Yuan
authors.initials: TY
authors.lastname: Hsieh
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taiwan.
authors.forename: Tzu-Ming
authors.initials: TM
authors.lastname: Ou
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taiwan. Electronic address: meindongsha@gmail.com.
authors.forename: Hsuan-Wei
authors.initials: HW
authors.lastname: Chen
mesh_terms: D016099:Endoscopy, Gastrointestinal / Q000009:adverse effects*; D004750:Enteral Nutrition / Q000295:instrumentation; D005774:Gastrostomy / Q000009:adverse effects* / Q000295:instrumentation; D006801:Humans; D009366:Neoplasm Seeding; D009959:Oropharyngeal Neoplasms / Q000601:surgery*; D011206:Povidone-Iodine / Q000494:pharmacology*; D013530:Surgical Wound Infection / Q000517:prevention & control*
chemical_list: D011206:Povidone-Iodine