title: Travel-associated antimicrobial drug-resistant nontyphoidal Salmonellae, 2004-2009.
abstract: To evaluate trends in and risk factors for acquisition of antimicrobial-drug resistant nontyphoidal Salmonella infections, we searched Oregon surveillance data for 2004-2009 for all culture-confirmed cases of salmonellosis. We defined clinically important resistance (CIR) as decreased susceptibility to ampicillin, ceftriaxone, ciprofloxacin, gentamicin, or trimethoprim/sulfamethoxazole. Of 2,153 cases, 2,127 (99%) nontyphoidal Salmonella isolates were obtained from a specific source (e.g., feces, urine, blood, or other normally sterile tissue) and had been tested for drug susceptibility. Among these, 347 (16%) isolates had CIR. The odds of acquiring CIR infection significantly increased each year. Hospitalization was more likely for patients with than without CIR infections. Among patients with isolates that had been tested, we analyzed data from 1,813 (84%) who were interviewed. Travel to eastern or Southeast Asia was associated with increased CIR. Isolates associated with outbreaks were less likely to have CIR. Future surveillance activities should evaluate resistance with respect to international travel.
authors.forename: Russell S
authors.initials: RS
authors.lastname: Barlow
authors.forename: Emilio E
authors.initials: EE
authors.lastname: Debess
authors.forename: Kevin L
authors.initials: KL
authors.lastname: Winthrop
authors.forename: Jodi A
authors.initials: JA
authors.lastname: Lapidus
authors.forename: Robert
authors.initials: R
authors.lastname: Vega
authors.forename: Paul R
authors.initials: PR
authors.lastname: Cieslak
mesh_terms: D000293:Adolescent; D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D002648:Child; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests / Q000379:methods; D008875:Middle Aged; D012307:Risk Factors; D012475:Salmonella / Q000302:isolation & purification*; D012478:Salmonella Food Poisoning / Q000453:epidemiology* / Q000382:microbiology; D012480:Salmonella Infections / Q000453:epidemiology* / Q000382:microbiology; D014195:Travel; D055815:Young Adult
chemical_list: D000890:Anti-Infective Agents
keywords: Asia; Salmonella; bacteria; communicable diseases; drug resistance; emerging; foodborne diseases; nontyphoidal; travel