title: pH-responsive robust polymer micelles with metal-ligand coordinated core cross-links.
abstract: We report on pH-responsive core-shell polymer micelles with catechol-Fe(3+) coordinated core cross-links, which provide robustness to drug-loaded polymer micelles and allow the facilitated intracellular release of loaded anticancer drugs in response to an endosomal acidic pH.
authors.affiliation: Department of Life and Nanopharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul 130-701, Korea.
authors.forename: Gyu Ha
authors.initials: GH
authors.lastname: Hwang
authors.forename: Kyung Hyun
authors.initials: KH
authors.lastname: Min
authors.forename: Hong Jae
authors.initials: HJ
authors.lastname: Lee
authors.forename: Hye Young
authors.initials: HY
authors.lastname: Nam
authors.forename: Gi Hyun
authors.initials: GH
authors.lastname: Choi
authors.forename: Byung Joo
authors.initials: BJ
authors.lastname: Kim
authors.forename: Seo Young
authors.initials: SY
authors.lastname: Jeong
authors.forename: Sang Cheon
authors.initials: SC
authors.lastname: Lee
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology; D002396:Catechols / Q000737:chemistry; D049109:Cell Proliferation / Q000187:drug effects; D004317:Doxorubicin / Q000737:chemistry / Q000494:pharmacology; D004337:Drug Carriers / Q000737:chemistry; D005290:Ferric Compounds / Q000737:chemistry*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008024:Ligands; D061986:MCF-7 Cells; D008823:Micelles; D011108:Polymers / Q000737:chemistry*
chemical_list: D000970:Antineoplastic Agents; D002396:Catechols; D004337:Drug Carriers; D005290:Ferric Compounds; D008024:Ligands; D008823:Micelles; D011108:Polymers; D004317:Doxorubicin; C034221:catechol