title: Alternative technique for calcium phosphate coating on titanium alloy implants.
abstract: As an alternative technique for calcium phosphate coating on titanium alloys, we propose to functionalize the metal surface with anionic bath containing chlorides of palladium or silver as activators. This new deposition route has several advantages such as controlled conditions, applicability to complex shapes, no adverse effect of heating, and cost effectiveness. A mixture of hydroxyapatite and calcium phosphate hydrate is deposited on the surface of Ti-6Al-4V. Calcium phosphate coating is built faster compared with the one by Simulated Body Fluid. Cell morphology and density are comparable to the control one; and the results prove no toxic compound is released into the medium during the previous seven days of immersion. Moreover, the cell viability is comparable with cells cultivated with the virgin medium. These experimental treatments allowed producing cytocompatible materials potentially applicable to manufacture implantable devices for orthopedic and oral surgeries.
authors.affiliation: Institut de Physique et Chimie des Matériaux de Strasbourg CNRS-UMR 7504; Strasbourg, France.
authors.forename: Van Quang
authors.initials: VQ
authors.lastname: Le
authors.affiliation: Institut de Physique et Chimie des Matériaux de Strasbourg CNRS-UMR 7504; Strasbourg, France.
authors.forename: Geneviève
authors.initials: G
authors.lastname: Pourroy
authors.affiliation: Department of Health Sciences; Università del Piemonte Orientale "Amedeo Avogadro"; Novara, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Cochis
authors.affiliation: Department of Health Sciences; Università del Piemonte Orientale "Amedeo Avogadro"; Novara, Italy; Consorzio Interuniversitario Nazionale per la Scienza e Tecnologia dei Materiali; Firenze, Italy.
authors.forename: Lia
authors.initials: L
authors.lastname: Rimondini
authors.affiliation: Biomaterials Department; National Research Centre; Cairo, Egypt.
authors.forename: Wafa I
authors.initials: WI
authors.lastname: Abdel-Fattah
authors.affiliation: Biophysics Department; Ain Shams University; Cairo, Egypt.
authors.forename: Hadeer I
authors.initials: HI
authors.lastname: Mohammed
authors.affiliation: Institut de Physique et Chimie des Matériaux de Strasbourg CNRS-UMR 7504; Strasbourg, France.
authors.forename: Adele
authors.initials: A
authors.lastname: Carradò
mesh_terms: D000497:Alloys / Q000737:chemistry*; D001826:Body Fluids / Q000737:chemistry; D002130:Calcium Phosphates / Q000737:chemistry*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D017886:Durapatite; D006801:Humans; D019736:Prostheses and Implants; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*
chemical_list: D000497:Alloys; D002130:Calcium Phosphates; D020099:Coated Materials, Biocompatible; D017886:Durapatite; C020243:calcium phosphate; D014025:Titanium
keywords: calcium-phosphate; chemical route; hydroxyapatite; physico-chemical characterization; titanium alloy