title: Melanin transfer: the keratinocytes are more than gluttons.
abstract: Skin pigmentation is tightly linked to the transfer of melanin from melanocytes to neighboring keratinocytes. For decades, cellular mechanisms underlying pigment transfer have remained enigmatic. Tarafder et al. identify a keratinocyte-initiated process coupling the exocytosis and endocytosis of melanin as a major pigment transfer mode in epidermis. These findings open new paths in our understanding of melanocyte-keratinocyte communication regulating pigmentation.
authors.affiliation: Institut Curie, Centre de Recherche, Paris, France; Structure and Membrane Compartments, CNRS UMR144, Paris, France. Electronic address: cedric.delevoye@curie.fr.
authors.forename: Cédric
authors.initials: C
authors.lastname: Delevoye
mesh_terms: D006801:Humans; D015603:Keratinocytes / Q000378:metabolism*; D008543:Melanins / Q000378:metabolism*; D008544:Melanocytes / Q000378:metabolism*; D012867:Skin / Q000378:metabolism*; D020691:rab GTP-Binding Proteins / Q000378:metabolism*; D000099193:rab11 GTP-Binding Proteins
chemical_list: D008543:Melanins; D020691:rab GTP-Binding Proteins; D000099193:rab11 GTP-Binding Proteins