title: [Combined variable immunodeficiency with unusal features. A case report].
abstract: BACKGROUND
  The association granulomatosis - combined variable immunodeficiency (CVID) - is well known from the clinicians. However, the association with a large granular lymphocyte (LGL) leukemia has not been yet reported.
  
  
  METHODS
  We report a 50-year-old woman, followed for CVID associated with a granulomatous disease. During the follow-up, the patient developed a granulomatous lymphocytic interstitiel lung disease (GLILD). Secondarily, she presented a LGL leukemia.
  
  
  CONCLUSIONS
  To our knowledge, this is the first reported case of an association between CVID and LGL leukemia.
authors.affiliation: Service de médecine interne-oncologie, HIA Desgenettes, 108, boulevard Pinel, 69003 Lyon, France. Electronic address: f.decharry@gmail.com.
authors.forename: F
authors.initials: F
authors.lastname: De Charry
authors.affiliation: Service médecine interne, groupe hospitalier mutualiste, 8, rue Docteur-Calmette, 38000 Grenoble, France.
authors.forename: A
authors.initials: A
authors.lastname: Peterschmitt Tonetti
authors.affiliation: Service d'imagerie médicale, HIA Desgenettes, 108, boulevard Pinel, 69003 Lyon, France.
authors.forename: C
authors.initials: C
authors.lastname: De Charry
authors.affiliation: Laboratoire d'hématologie cellulaire, centre hospitalier Lyon Sud, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite cedex, France.
authors.forename: L
authors.initials: L
authors.lastname: Baseggio
authors.affiliation: Service de médecine interne-oncologie, HIA Desgenettes, 108, boulevard Pinel, 69003 Lyon, France.
authors.forename: F
authors.initials: F
authors.lastname: Pasquet
authors.affiliation: Service de médecine interne-oncologie, HIA Desgenettes, 108, boulevard Pinel, 69003 Lyon, France.
authors.forename: S
authors.initials: S
authors.lastname: Khenifer
authors.affiliation: Service de médecine interne-oncologie, HIA Desgenettes, 108, boulevard Pinel, 69003 Lyon, France.
authors.forename: R
authors.initials: R
authors.lastname: Rassat
authors.affiliation: Service de médecine interne-oncologie, HIA Desgenettes, 108, boulevard Pinel, 69003 Lyon, France.
authors.forename: M
authors.initials: M
authors.lastname: Pavic
mesh_terms: D017074:Common Variable Immunodeficiency / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006099:Granuloma / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged; D013902:Radiography, Thoracic
keywords: Atteinte pulmonaire; Combined variable immunodeficiency; Déficit immunitaire commun variable; Granulomatose; Granulomatosis; Large granular lymphocyte (LGL) leukemia; Leucémie à grands lymphocytes à grains; Lung disease