title: Evolution of surgical microwave ablation for the treatment of colorectal cancer liver metastasis: review of the literature and a single centre experience.
abstract: Surgical resection is the gold standard treatment for colorectal liver metastasis, with reported five-year survival rates of 40 %. Unfortunately, despite progress in systemic therapies and surgical techniques, only 20-30 % of patients can be offered this potentially curative treatment modality. Ablative therapies have recently been suggested to treat unresectable lesions or to extend the margins of resectability. Additionally, cases of local recurrence after hepatic surgery might require alternative strategies and options for re-intervention. Microwave ablation (MWA) has recently become a matter of particular interest for such indications. We, herein, present a review of the literature published between January 1999 and June 2013 from a database search with the following keywords: microwave, ablation, liver metastases, colorectal neoplasm, resection, hepatectomy, colonic neoplasm, cancer. Furthermore, we provide insight based on our own data for 28 consecutive patients who underwent hepatic resection combined with MWA from 2005 to 2012 in a single centre.
authors.affiliation: Department of General and Hepatobiliary Surgery, University Hospital Aintree, Longmoor Lane, Liverpool, L97AL, UK, s.staettner@salk.at.
authors.forename: Stefan
authors.initials: S
authors.lastname: Stättner
authors.forename: Florian
authors.initials: F
authors.lastname: Primavesi
authors.forename: Vincent S
authors.initials: VS
authors.lastname: Yip
authors.forename: Robert P
authors.initials: RP
authors.lastname: Jones
authors.forename: Dietmar
authors.initials: D
authors.lastname: Öfner
authors.forename: Hassan Z
authors.initials: HZ
authors.lastname: Malik
authors.forename: Stephen W
authors.initials: SW
authors.lastname: Fenwick
authors.forename: Graeme J
authors.initials: GJ
authors.lastname: Poston
mesh_terms: D055011:Ablation Techniques / Q000379:methods*; D015179:Colorectal Neoplasms / Q000473:pathology* / Q000601:surgery*; D006498:Hepatectomy; D006801:Humans; D010535:Laparoscopy; D007813:Laparotomy; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*; D008872:Microwaves / Q000627:therapeutic use*; D025321:Surgery, Computer-Assisted / Q000379:methods