title: The neurosurgical treatment of patients in dystonic state - overview of the literature.
abstract: Treatment options for patients in dystonic state include sedation, artificial ventilation, intrathecal baclofen infusions and stereotactic procedures. The main aim of this overview is the presentation and assessment of stereotactic procedures applied for treating patients in severe dystonic state. We performed literature overview starting from 1998 to 2012 with case reports regarding all patients treated by stereotactic procedures for dystonic state. We were able to find 15 articles describing 22 patients. Ablative procedures were described in 5 articles (3 thalamotomies, 3 pallidotomies) and were done in 6 patients. In the remaining 10 articles, globus pallidus internus stimulation was utilized in another 16 patients. We can conclude that bilateral pallidal deep brain stimulation seems to be the best stereotactic target for patients in dystonic state.
authors.affiliation: Department of Neurosurgery, Postgraduate Medical Center, Warsaw, Poland. Electronic address: mrsob@op.pl.
authors.forename: Michał Roman
authors.initials: MR
authors.lastname: Sobstyl
authors.affiliation: Department of Neurological-Psychiatric Nursing and Department of Neurology, Medical University of Gdansk and St. Adalbert Hospital, Gdansk, Poland.
authors.forename: Jarosław Wojciech
authors.initials: JW
authors.lastname: Sławek
authors.affiliation: Department of Neurosurgery, Postgraduate Medical Center, Warsaw, Poland.
authors.forename: Mirosław
authors.initials: M
authors.lastname: Ząbek
mesh_terms: D000293:Adolescent; D000978:Antiparkinson Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D046690:Deep Brain Stimulation; D004421:Dystonia / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D005260:Female; D005917:Globus Pallidus / Q000601:surgery; D006801:Humans; D007223:Infant; D007980:Levodopa / Q000627:therapeutic use; D008297:Male; D019635:Neurosurgical Procedures / Q000379:methods*; D053860:Pallidotomy; D013788:Thalamus / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000978:Antiparkinson Agents; D007980:Levodopa
keywords: Deep brain stimulation; Pallidal stimulation; Pallidotomy; Status dystonicus; Thalamotomy