title: Hurthle cell carcinoma presenting as a single choroid plexus metastasis.
abstract: Choroid plexus masses represent approximately 0.3-0.8% of intracranial tumors. Herein we present, to our knowledge, the first reported patient with an isolated Hurthle cell papillary thyroid carcinoma metastasis to the choroid plexus of the lateral ventricle. Unresponsive to iodine ablation and refusing surgery, the patient underwent Gamma Knife radiosurgery (Elekta AB, Stockholm, Sweden), receiving 15Gy to the 50% isodose line. The lesion regressed until 5years later at which time it was unresponsive to 18Gy and required surgical resection. Although extraneural metastatic cancers are recognized as potential sources for the single choroid plexus mass, we must consider even the unusual culprit in patients with a history of cancer.
authors.affiliation: Department of Neurosurgery, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA. Electronic address: athealy@msn.com.
authors.forename: Andrew T
authors.initials: AT
authors.lastname: Healy
authors.affiliation: Case Western Reserve University, Lerner College of Medicine, Cleveland, OH, USA.
authors.forename: Balint
authors.initials: B
authors.lastname: Otvos
authors.affiliation: Department of Neurosurgery, University of Toledo, Toledo, OH, USA.
authors.forename: Jason
authors.initials: J
authors.lastname: Schroeder
authors.affiliation: Department of Endocrinology, Diabetes and Metabolism, Cleveland Clinic, Cleveland, OH, USA.
authors.forename: Amir H
authors.initials: AH
authors.lastname: Hamrahian
authors.affiliation: Department of Neurosurgery, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
authors.forename: Lilyana
authors.initials: L
authors.lastname: Angelov
authors.affiliation: Department of Neurosurgery, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
authors.forename: Kambiz
authors.initials: K
authors.lastname: Kamian
mesh_terms: D018249:Adenoma, Oxyphilic; D000368:Aged; D002277:Carcinoma / Q000473:pathology* / Q000601:surgery; D002291:Carcinoma, Papillary; D016545:Choroid Plexus Neoplasms / Q000556:secondary* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D020547:Lateral Ventricles; D008279:Magnetic Resonance Imaging; D016634:Radiosurgery; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000601:surgery
keywords: Central nervous system metastases; Choroid plexus; Hurthle cell carcinoma; Intraventricular mass