title: Small lymphocytic lymphoma presenting as a paraneoplastic syndrome with acute central nervous system demyelination.
authors.affiliation: Department of Internal Medicine, Tufts Medical Center, Boston, MA. Electronic address: ndevito@tuftsmedicalcenter.org.
authors.forename: Nicholas
authors.initials: N
authors.lastname: DeVito
authors.affiliation: Department of Neurology, Tufts Medical Center, Boston, MA.
authors.forename: Kit
authors.initials: K
authors.lastname: Mui
authors.affiliation: Department of Neurology, Tufts Medical Center, Boston, MA.
authors.forename: Yasir
authors.initials: Y
authors.lastname: Jassam
authors.affiliation: Department of Neurology, Tufts Medical Center, Boston, MA; Department of Hematology-Oncology, Tufts Medical Center, Boston, MA.
authors.forename: Lynne
authors.initials: L
authors.lastname: Taylor
authors.affiliation: Department of Pathology, Tufts Medical Center, Boston, MA.
authors.forename: Monika
authors.initials: M
authors.lastname: Pilichowska
authors.affiliation: Department of Hematology-Oncology, Tufts Medical Center, Boston, MA.
authors.forename: Furha
authors.initials: F
authors.lastname: Cossor
mesh_terms: D000368:Aged; D058846:Antibodies, Monoclonal, Murine-Derived / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D001921:Brain / Q000473:pathology; D003520:Cyclophosphamide / Q000627:therapeutic use; D003711:Demyelinating Diseases / Q000150:complications* / Q000175:diagnosis; D003937:Diagnosis, Differential; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D008198:Lymph Nodes / Q000473:pathology; D008279:Magnetic Resonance Imaging; D010257:Paraneoplastic Syndromes / Q000150:complications* / Q000175:diagnosis*; D011241:Prednisone / Q000627:therapeutic use; D000069283:Rituximab; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; C571759:R-CHOP protocol; D000069283:Rituximab; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone
keywords: Aggressive variant of CLL; CNS demyelination; Chronic lymphocytic leukemia; Neurological paraneoplastic syndrome; Small lymphocytic lymphoma