title: Cohort profile: the Hawai'i Family Study of Cognition.
abstract: Intergenerational longitudinal studies over the lifespan provide valuable information for understanding the contexts and dynamic relations among cognition, family and health in adults and the elderly. The Hawai'i Family Study of Cognition (HFSC), initiated in the early 1970s, included a cohort of over 6500 individuals representing over 1800 families of parents and their offspring. The HFSC gathered data on cognitive, personality, biological and other psychosocial variables, and provided novel information on the nature of cognitive abilities, especially on family issues. Some families were reassessed with short-term retesting in the 1970s. A select sample of offspring and their siblings and spouses were re-measured in the 1980s. Decades later, a 40-year follow-up of the original HFSC cohort was facilitated by the availability of contemporary tracking and tracing methods and internet-based testing. A subgroup of the original HFSC participants was re-contacted and retested on contemporary cognitive as well as socio-demographic and health measures. In this paper, we describe the original HFSC cohort and the design and methodology of the re-contact and retest studies of the HFSC, plans for expanding the re-contact and retesting, as well as directions for future research and collaborations. The Principal Investigator may be contacted for more information regarding the application, review and approval process for data access requests from qualified individuals outside the project.
authors.affiliation: Department of Psychiatry, University of Hawai'i at Mānoa, Honolulu, Hawai'i, USA, Queen's Medical Center, Honolulu, Hawai'i, USA, Department of Psychology, University of Southern California, Los Angeles, CA, USA, Longitudinal Research Institute, Charlottesville, VA, USA and National Institute on Aging, Behavioral Epidemiology Section, Baltimore, MD, USA Department of Psychiatry, University of Hawai'i at Mānoa, Honolulu, Hawai'i, USA, Queen's Medical Center, Honolulu, Hawai'i, USA, Department of Psychology, University of Southern California, Los Angeles, CA, USA, Longitudinal Research Institute, Charlottesville, VA, USA and National Institute on Aging, Behavioral Epidemiology Section, Baltimore, MD, USA onoyej@dop.hawaii.edu.
authors.forename: Jane M M
authors.initials: JM
authors.lastname: Onoye
authors.affiliation: Department of Psychiatry, University of Hawai'i at Mānoa, Honolulu, Hawai'i, USA, Queen's Medical Center, Honolulu, Hawai'i, USA, Department of Psychology, University of Southern California, Los Angeles, CA, USA, Longitudinal Research Institute, Charlottesville, VA, USA and National Institute on Aging, Behavioral Epidemiology Section, Baltimore, MD, USA.
authors.forename: Earl S
authors.initials: ES
authors.lastname: Hishinuma
authors.affiliation: Department of Psychiatry, University of Hawai'i at Mānoa, Honolulu, Hawai'i, USA, Queen's Medical Center, Honolulu, Hawai'i, USA, Department of Psychology, University of Southern California, Los Angeles, CA, USA, Longitudinal Research Institute, Charlottesville, VA, USA and National Institute on Aging, Behavioral Epidemiology Section, Baltimore, MD, USA Department of Psychiatry, University of Hawai'i at Mānoa, Honolulu, Hawai'i, USA, Queen's Medical Center, Honolulu, Hawai'i, USA, Department of Psychology, University of Southern California, Los Angeles, CA, USA, Longitudinal Research Institute, Charlottesville, VA, USA and National Institute on Aging, Behavioral Epidemiology Section, Baltimore, MD, USA.
authors.forename: John J
authors.initials: JJ
authors.lastname: McArdle
authors.affiliation: Department of Psychiatry, University of Hawai'i at Mānoa, Honolulu, Hawai'i, USA, Queen's Medical Center, Honolulu, Hawai'i, USA, Department of Psychology, University of Southern California, Los Angeles, CA, USA, Longitudinal Research Institute, Charlottesville, VA, USA and National Institute on Aging, Behavioral Epidemiology Section, Baltimore, MD, USA.
authors.forename: Alan B
authors.initials: AB
authors.lastname: Zonderman
authors.affiliation: Department of Psychiatry, University of Hawai'i at Mānoa, Honolulu, Hawai'i, USA, Queen's Medical Center, Honolulu, Hawai'i, USA, Department of Psychology, University of Southern California, Los Angeles, CA, USA, Longitudinal Research Institute, Charlottesville, VA, USA and National Institute on Aging, Behavioral Epidemiology Section, Baltimore, MD, USA onoyej@dop.hawaii.edu.
authors.forename: R Janine
authors.initials: RJ
authors.lastname: Bumanglag
authors.affiliation: Department of Psychiatry, University of Hawai'i at Mānoa, Honolulu, Hawai'i, USA, Queen's Medical Center, Honolulu, Hawai'i, USA, Department of Psychology, University of Southern California, Los Angeles, CA, USA, Longitudinal Research Institute, Charlottesville, VA, USA and National Institute on Aging, Behavioral Epidemiology Section, Baltimore, MD, USA Department of Psychiatry, University of Hawai'i at Mānoa, Honolulu, Hawai'i, USA, Queen's Medical Center, Honolulu, Hawai'i, USA, Department of Psychology, University of Southern California, Los Angeles, CA, USA, Longitudinal Research Institute, Charlottesville, VA, USA and National Institute on Aging, Behavioral Epidemiology Section, Baltimore, MD, USA.
authors.forename: Junji
authors.initials: J
authors.lastname: Takeshita
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003071:Cognition / Q000502:physiology*; D004522:Educational Status; D005163:Factor Analysis, Statistical; D005190:Family; D005260:Female; D006254:Hawaii; D006801:Humans; D007360:Intelligence / Q000235:genetics / Q000502:physiology*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D009790:Occupations; D010551:Personality; D011446:Prospective Studies; D012923:Social Class; D055815:Young Adult
keywords: Cognition; ethnic groups; family; longitudinal studies