title: Chemotherapy or radiation-induced oral mucositis.
abstract: Oral mucositis is a significant toxicity of systemic chemotherapy and of radiation therapy to the head and neck region. The morbidity of oral mucositis can include pain, nutritional compromise, impact on quality of life, alteration in cancer therapy, risk for infection, and economic costs. Management includes general symptomatic support and targeted therapeutic interventions for the prevention or treatment of oral mucositis. Evidence-based clinical practice guidelines are available to guide clinicians in the selection of effective management strategies.
authors.affiliation: Section of Oral Medicine, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030-1605, USA. Electronic address: Lalla@uchc.edu.
authors.forename: Rajesh V
authors.initials: RV
authors.lastname: Lalla
authors.affiliation: Department of Dental Oncology, Northeast Cancer Centre, Health Sciences North, Northern Ontario School of Medicine, 41 Ramsey Lake Road, Sudbury, ON P3E 5J1, Canada.
authors.forename: Deborah P
authors.initials: DP
authors.lastname: Saunders
authors.affiliation: Section of Oral Medicine, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030-1605, USA.
authors.forename: Douglas E
authors.initials: DE
authors.lastname: Peterson
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D017281:Cost of Illness; D006801:Humans; D009748:Nutrition Disorders / Q000209:etiology; D010146:Pain / Q000209:etiology; D010347:Patient Care Planning; D017410:Practice Guidelines as Topic; D011788:Quality of Life; D011878:Radiotherapy / Q000009:adverse effects*; D013280:Stomatitis / Q000139:chemically induced* / Q000209:etiology / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents
keywords: Cancer; Chemotherapy; Oral mucositis; Radiation therapy; Stomatitis