title: Pyuric diabetic patients: A tertiary centre experience from Karachi.
abstract: OBJECTIVE
  (1) To determine frequency of urinary tract infection among pyuric diabetic patients. (2) To determine sterile pyuria frequency among pyuric diabetic patients. (3) To determine factors predisposing to urinary tract infection.
  
  
  METHODS
  This is a non randomized, prospective observational study done in tertiary care set up of Dow University of Health Sciences, Karachi. Data collection done from June 2013 till August 2013. Sampling was done by convenient method, sample size of 97. Inclusion criteria was all adult (above 16) patients with diabetes mellitus and pyuria (more than 4 pus cells /HPF) whose urine culture report was also available. Verbal consent was sought from patients. All data was collected on a Performa. Data was maintained and analyzed on SPSS version 16.
  
  
  RESULTS
  Total number of pyuric diabetic patients in study was 97. Frequency of Urinary tract infection was 59/97 (60.82%), prevalence of culture negative sterile pyuria was found 38/97 (39.17%). Urinary tract infection was found to be more in females with lower urinary tract symptoms and flank pains. Stone disease, obstructed pelvicalyceal system, proteinuria, high serum creatinine and positive nitrites were found more in culture positive patients than in culture negative pyuric patients.
  
  
  CONCLUSIONS
  Pyuric diabetic patients in our study population were found to have culture positive UTI in 60.82% and culture negative sterile pyuria among 39.17% of patients. UTI was found more in females, in symptomatic patient and with abnormal urinary tract anatomy and function.
authors.affiliation: Dr. Huma Mamun Mahmud, MBBS, MCPS (Medicine), FCPS (Nephrology), Assistant Professor, Consultant Nephrologist, Department of Medicine, Dow International Medical College, Dow University of Heath Sciences, Dow International Medical College (Ojha Campus), DUHS, Suparco Road, off Main University Road, Gulzar-e-Hijri, Scheme 33, Karachi, Pakistan.
authors.forename: Huma
authors.initials: H
authors.lastname: Mamun Mahmud
authors.affiliation: Dr. Sobia Qureshi, MBBS, Senior Medical Officer, Dow International Medical College, Dow University of Heath Sciences, Dow International Medical College (Ojha Campus), DUHS, Suparco Road, off Main University Road, Gulzar-e-Hijri, Scheme 33, Karachi, Pakistan.
authors.forename: Sobia
authors.initials: S
authors.lastname: Qureshi
authors.affiliation: Dr. Darshan Kumar, MBBS, FCPS (Medicine), Assistant Professor, National Institute of Diabetes and Endocrinology. Dow International Medical College, Dow University of Heath Sciences, Dow International Medical College (Ojha Campus), DUHS, Suparco Road, off Main University Road, Gulzar-e-Hijri, Scheme 33, Karachi, Pakistan.
authors.forename: Darshan
authors.initials: D
authors.lastname: Kumar
authors.affiliation: Dr. Syed Farman, Dow International Medical College, Dow University of Heath Sciences, Dow International Medical College (Ojha Campus), DUHS, Suparco Road, off Main University Road, Gulzar-e-Hijri, Scheme 33, Karachi, Pakistan.
authors.forename: Syed
authors.initials: S
authors.lastname: Farman
keywords: Diabetes; Sterile pyuria; UTI