title: Differentiation between calcification and hemorrhage in brain tumors using susceptibility-weighted imaging: a pilot study.
abstract: OBJECTIVE
  Our aim was to develop a robust method to differentiate calcification from hemorrhage in gliomas. Histopathologic examination was performed to validate hemorrhage and calcification.
  
  
  CONCLUSIONS
  Phase images from eleven patients with glioma yielded statistically significant phase-shift values for calcification and hemorrhage compared with normal brain, whereas CT showed substantial overlap of Hounsfield units. Phase image analysis correctly differentiated between intratumoral calcification and hemorrhage in 86% of cases.
authors.affiliation: 1 Department of Radiology, Cantonal Hospital Aarau, Tellstrasse, CH-5001 Aarau, Switzerland.
authors.forename: Jatta
authors.initials: J
authors.lastname: Berberat
authors.forename: Rainer
authors.initials: R
authors.lastname: Grobholz
authors.forename: Larissa
authors.initials: L
authors.lastname: Boxheimer
authors.forename: Susanne
authors.initials: S
authors.lastname: Rogers
authors.forename: Luca
authors.initials: L
authors.lastname: Remonda
authors.forename: Ulrich
authors.initials: U
authors.lastname: Roelcke
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000473:pathology*; D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D005910:Glioma / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed