title: From neurogenetic studies in the fly brain to a concept in circadian biology.
abstract: This paper is dedicated to Karl-Friedrich Fischbach, who has always shared with me the interest in the function of the fly brain, especially that of its optic lobes. He has accompanied me during my first steps in scientific research. The paper tells the story how our first common attempts to localize the circadian clock in the fly brain finally helped in phrasing the two-oscillator principle of circadian clocks that seems to be valid far beyond the fly circadian system. I hope that Karl-Friedrich will take this story as praise for his generosity in supporting younger scientists outside his own lab, even without the reward of a common paper.
authors.affiliation: Neurobiology and Genetics, Biocenter, Theodor-Boveri Institute, University of Würzburg , Würzburg , Germany.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Helfrich-Förster
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism*; D002940:Circadian Rhythm / Q000502:physiology*; D029721:Drosophila Proteins / Q000378:metabolism; D004331:Drosophila melanogaster / Q000378:metabolism; D009474:Neurons / Q000378:metabolism*
chemical_list: D029721:Drosophila Proteins
keywords: Drosophila melanogaster; circadian clock; dual-oscillator model; photoperiod; pigment-dispersing factor