title: Treatment of painful hypertrophic osteoarthropathy associated with non-small cell lung cancer with octreotide: a case report and review of the literature.
abstract: Hypertrophic osteoarthropathy (HOA) is a syndrome most commonly associated with non-small cell lung cancer and consists of periostitis, digital clubbing and painful polyarthropathy. Its symptoms may be disabling and are reportedly difficult to manage effectively with conventional analgesia. We present a case of a lung cancer patient with opioid resistant painful HOA in whom analgesia was achieved with octreotide.
authors.affiliation: Department of Palliative Medicine, Royal Gwent Hospital, Newport, UK.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Birch
authors.forename: Debbie
authors.initials: D
authors.lastname: Jenkins
authors.forename: Simon
authors.initials: S
authors.lastname: Noble
mesh_terms: D000230:Adenocarcinoma / Q000150:complications*; D000368:Aged; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D015282:Octreotide / Q000627:therapeutic use*; D010005:Osteoarthropathy, Secondary Hypertrophic / Q000188:drug therapy* / Q000209:etiology; D010146:Pain / Q000188:drug therapy* / Q000209:etiology
chemical_list: D018931:Antineoplastic Agents, Hormonal; D015282:Octreotide