title: Synthesis of PEGylated low generation dendrimer-entrapped gold nanoparticles for CT imaging applications.
abstract: Dendrimer-entrapped gold nanoparticles (Au DENPs) can be formed using low-generation dendrimers pre-modified by polyethylene glycol (PEG). The formed PEGylated Au DENPs with desirable stability, cytocompatibility, and X-ray attenuation properties enable efficient computed tomography imaging of the heart and tumor model of mice.
authors.affiliation: State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Donghua University, Shanghai 201620, People's Republic of China.
authors.forename: Hui
authors.initials: H
authors.lastname: Liu
authors.forename: Han
authors.initials: H
authors.lastname: Wang
authors.forename: Yanhong
authors.initials: Y
authors.lastname: Xu
authors.forename: Mingwu
authors.initials: M
authors.lastname: Shen
authors.forename: Jinglong
authors.initials: J
authors.lastname: Zhao
authors.forename: Guixiang
authors.initials: G
authors.lastname: Zhang
authors.forename: Xiangyang
authors.initials: X
authors.lastname: Shi
mesh_terms: D000818:Animals; D003287:Contrast Media / Q000138:chemical synthesis* / Q000737:chemistry; D050091:Dendrimers / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D006321:Heart / Q000000981:diagnostic imaging; D053768:Metal Nanoparticles / Q000737:chemistry*; D051379:Mice; D009369:Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging; D011092:Polyethylene Glycols / Q000737:chemistry*; D014057:Tomography, X-Ray Computed; D001743:Urinary Bladder / Q000000981:diagnostic imaging
chemical_list: D003287:Contrast Media; D050091:Dendrimers; D011092:Polyethylene Glycols; D006046:Gold