title: Acquired idiopathic lipoatrophic panniculitis in a 12-month-old infant.
abstract: Lipoatrophic panniculitis is a rare condition affecting mainly children, often associated with connective tissue disease. We report a healthy 12-month-old girl with no clinical or laboratory features of connective tissue disease who presented with the progressive appearance of annular atrophic plaques beginning at the left arm. A histopathological analysis revealed lobular panniculitis, with fat necrosis and an associated inflammatory infiltrate supporting the diagnosis of lipoatrophic panniculitis. Lipoatrophic panniculitis should be considered in infants and young children with clinical features of panniculitis and fat atrophy even without clinical or serologic evidence of connective tissue disease.
authors.affiliation: Dermatology Department, Royal Children's Hospital, Melbourne, Victoria, Australia.|Paediatrics Department, Institute Pediatrik, Kuala Lumpur General Hospital, Kuala Lumpur, Wilayah Persekutuan, Malaysia.
authors.forename: Su Yuen
authors.initials: SY
authors.lastname: Ng
authors.affiliation: Anatomical Pathology Department, Royal Children's Hospital, Melbourne, Victoria, Australia.
authors.forename: Colleen
authors.initials: C
authors.lastname: D'Arcy
authors.affiliation: Dermatology Department, Royal Children's Hospital, Melbourne, Victoria, Australia.
authors.forename: David
authors.initials: D
authors.lastname: Orchard
mesh_terms: D001284:Atrophy; D005260:Female; D006801:Humans; D007223:Infant; D009336:Necrosis; D015434:Panniculitis / Q000175:diagnosis* / Q000473:pathology*; D050151:Subcutaneous Fat / Q000473:pathology*
keywords: connective tissue disease; lipoatrophic panniculitis; lipoatrophy; paediatric dermatology