title: [Spontaneous intrahepatic hematoma: an unexpected etiology].
abstract: BACKGROUND
  Diagnosis of AL amyloidosis can be complicated by the diversity and the absence of specificity of symptoms.
  
  
  METHODS
  We report a patient who presented with a non-traumatic hepatic hematoma, leading to the discovery of hepatic amyloidosis secondary to probable multiple myeloma. The originality of our report lies in the discovery of two acquired abnormalities of haemostasis: a factor X deficiency and an acquired von Willebrand syndrome, by a likely inhibitor.
  
  
  CONCLUSIONS
  Our case report is a reminder of the importance of haemostasis analysis in AL amyloidosis.
authors.affiliation: Service de médecine interne, CHU, 147, avenue du Maréchal-Juin, 76230 Bois-Guillaume, France.
authors.forename: M
authors.initials: M
authors.lastname: Khetta
authors.affiliation: Service d'hépato-gastro-entérologie, CHU Charles-Nicolle, 1, rue de Germont, 76031 Rouen cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Lemaître
authors.affiliation: Laboratoire d'hémostase, CHU Charles-Nicolle, 1, rue de Germont, 76031 Rouen cedex, France; Inserm U 1096, CHU de Rouen, 76031 Rouen cedex, France.
authors.forename: V
authors.initials: V
authors.lastname: Lecam Duchez
authors.affiliation: Service de médecine interne, CHU, 147, avenue du Maréchal-Juin, 76230 Bois-Guillaume, France; Inserm U 1096, CHU de Rouen, 76031 Rouen cedex, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Benhamou
authors.affiliation: Centre Henri-Becquerel, rue d'Amiens, 76038 Rouen cedex, France.
authors.forename: S
authors.initials: S
authors.lastname: Leprêtre
authors.affiliation: Service de radiologie, CHU Charles-Nicolle, 1, rue de Germont, 76031 Rouen cedex, France.
authors.forename: E
authors.initials: E
authors.lastname: Köning
authors.affiliation: Service de médecine interne, CHU, 147, avenue du Maréchal-Juin, 76230 Bois-Guillaume, France; Inserm U 1096, CHU de Rouen, 76031 Rouen cedex, France.
authors.forename: H
authors.initials: H
authors.lastname: Lévesque
authors.affiliation: Service d'hépato-gastro-entérologie, CHU Charles-Nicolle, 1, rue de Germont, 76031 Rouen cedex, France; Inserm U 1073, CHU de Rouen, 76031 Rouen cedex, France.
authors.forename: G
authors.initials: G
authors.lastname: Savoye
authors.affiliation: Service d'hépato-gastro-entérologie, CHU Charles-Nicolle, 1, rue de Germont, 76031 Rouen cedex, France. Electronic address: odile.goria@chu-rouen.fr.
authors.forename: O
authors.initials: O
authors.lastname: Goria
mesh_terms: D000686:Amyloidosis / Q000150:complications* / Q000175:diagnosis; D005171:Factor X Deficiency / Q000150:complications / Q000175:diagnosis; D005260:Female; D006406:Hematoma / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D000075363:Immunoglobulin Light-chain Amyloidosis; D008107:Liver Diseases / Q000175:diagnosis / Q000209:etiology*; D008875:Middle Aged; D014842:von Willebrand Diseases / Q000150:complications / Q000175:diagnosis
keywords: Acquired von Willebrand syndrome; Amyloidosis; Amylose; Hepatic hematoma; Hématome hépatique; Multiple myeloma; Myélome multiple; Syndrome de Willebrand acquis