title: A fibronectin-derived cell survival peptide belongs to a new class of epiviosamines.
abstract: In this issue, Lin et al. report the discovery of P12, a 14 amino acid peptide from the first fibronectin (FN) type III domain of FN, which has the capability of enhancing cell survival in culture and improving wound healing in rat skin. P12 belongs to a new class of bioactive peptides that they have named epiviosamines. Epiviosamines may have clinical applications.
authors.affiliation: Department of Cell Biology, Duke University Medical Center, Durham, North Carolina, USA. Electronic address: tomoo.ohashi@duke.edu.
authors.forename: Tomoo
authors.initials: T
authors.lastname: Ohashi
mesh_terms: D000818:Animals; D000077214:Becaplermin; D002470:Cell Survival; D005347:Fibroblasts / Q000378:metabolism*; D005353:Fibronectins / Q000737:chemistry*; D006801:Humans; D010455:Peptides / Q000737:chemistry*; D020574:Proto-Oncogene Proteins c-sis / Q000737:chemistry*; D012867:Skin / Q000378:metabolism*
chemical_list: D005353:Fibronectins; D010455:Peptides; D020574:Proto-Oncogene Proteins c-sis; D000077214:Becaplermin