title: Ocular graft versus host disease following allogeneic stem cell transplantation: a review of current knowledge and recommendations.
abstract: Graft versus host disease (GVHD) is a common complication of allogeneic stem cell transplantation (allo-SCT). Ocular GVHD develops in approximately 40-60% of patients following allo-SCT and its most common clinical manifestations include keratoconjunctivitis sicca and cicatricial conjunctivitis. Ocular GVHD may lead to severe ocular surface disease, which can significantly diminish quality of life and restrict daily activities. It is thus important to monitor the condition closely since with timely diagnosis, irreversible damage can be avoided. The current review will focus on updated information regarding ocular GVHD.
authors.affiliation: Jules Stein Eye Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
authors.forename: Nariman
authors.initials: N
authors.lastname: Nassiri
authors.affiliation: Department of Ophthalmology & Visual Sciences, University of Illinois at Chicago, Chicago, IL, USA.
authors.forename: Medi
authors.initials: M
authors.lastname: Eslani
authors.affiliation: Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Nekoo
authors.initials: N
authors.lastname: Panahi
authors.affiliation: Jules Stein Eye Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
authors.forename: Shiva
authors.initials: S
authors.lastname: Mehravaran
authors.affiliation: Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA.
authors.forename: Alireza
authors.initials: A
authors.lastname: Ziaei
authors.affiliation: Department of Ophthalmology & Visual Sciences, University of Illinois at Chicago, Chicago, IL, USA.
authors.forename: Ali R
authors.initials: AR
authors.lastname: Djalilian
keywords: Allogeneic Stem Cell Transplantation; Bone Marrow Transplantation; Dry Eye; Keratoconjunctivitis Sicca; Ocular Graft Versus Host Disease