title: Alimentary habits, physical activity, and Framingham global risk score in metabolic syndrome.
abstract: BACKGROUND
  Metabolic syndrome is a complex disorder represented by a set of cardiovascular risk factors. A healthy lifestyle is strongly related to improve Quality of Life and interfere positively in the control of risk factors presented in this condition.
  
  
  OBJECTIVE
  To evaluate the effect of a program of lifestyle modification on the Framingham General Cardiovascular Risk Profile in subjects diagnosed with metabolic syndrome.
  
  
  METHODS
  A sub-analysis study of a randomized clinical trial controlled blind that lasted three months. Participants were randomized into four groups: dietary intervention + placebo (DIP), dietary intervention + supplementation of omega 3 (fish oil 3 g/day) (DIS3), dietary intervention + placebo + physical activity (DIPE) and dietary intervention + physical activity + supplementation of omega 3 (DIS3PE). The general cardiovascular risk profile of each individual was calculated before and after the intervention.
  
  
  RESULTS
  The study included 70 subjects. Evaluating the score between the pre and post intervention yielded a significant value (p < 0.001). We obtained a reduction for intermediate risk in 25.7% of subjects. After intervention, there was a significant reduction (p < 0.01) on cardiovascular age, this being more significant in groups DIP (5.2%) and DIPE (5.3%).
  
  
  CONCLUSIONS
  Proposed interventions produced beneficial effects for reducing cardiovascular risk score. This study emphasizes the importance of lifestyle modification in the prevention and treatment of cardiovascular diseases.
authors.forename: Thays Soliman
authors.initials: TS
authors.lastname: Soares
authors.forename: Carla Haas
authors.initials: CH
authors.lastname: Piovesan
authors.forename: Andréia da Silva
authors.initials: Ada S
authors.lastname: Gustavo
authors.forename: Fabrício Edler
authors.initials: FE
authors.lastname: Macagnan
authors.forename: Luiz Carlos
authors.initials: LC
authors.lastname: Bodanese
authors.forename: Ana Maria Pandolfo
authors.initials: AM
authors.lastname: Feoli
mesh_terms: D000328:Adult; D000367:Age Factors; D002318:Cardiovascular Diseases / Q000178:diet therapy / Q000209:etiology / Q000517:prevention & control*; D015444:Exercise / Q000502:physiology*; D005247:Feeding Behavior / Q000502:physiology*; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications*; D008875:Middle Aged; D015999:Multivariate Analysis; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D040242:Risk Reduction Behavior; D012737:Sex Factors; D013997:Time Factors; D016896:Treatment Outcome