title: A new bump in the epigenetic landscape.
abstract: In this issue of Molecular Cell, Cheng et al. describe an unexpected role for the histone methyltransferases MLL3 and MLL4 in the repression of tissue-specific promoters, a function that prevents precocious cell differentiation in the skeletal muscle lineage.
authors.affiliation: Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
authors.forename: Anand S
authors.initials: AS
authors.lastname: Bhagwat
authors.affiliation: Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA. Electronic address: vakoc@cshl.edu.
authors.forename: Christopher R
authors.initials: CR
authors.lastname: Vakoc
mesh_terms: D000818:Animals; D002843:Chromatin; D018507:Gene Expression Regulation, Developmental; D006657:Histones / Q000235:genetics*; D006801:Humans; D024510:Muscle Development / Q000235:genetics*; D032446:Myoblasts / Q000378:metabolism*
chemical_list: D002843:Chromatin; D006657:Histones