title: Imaging methods for detection of chemotherapy-associated cardiotoxicity and dysfunction.
abstract: Survival in cancer has improved, shifting some of the focus of care to minimizing the long term complications of cancer therapy. Cardiovascular disease is a leading long-term cause of morbidity and mortality in patients who survive cancer. In the review we will focus on imaging techniques that are used to detect the cardiovascular consequences of chemotherapy. We will differentiate cardiotoxicity and cardiac injury from cardiac dysfunction and cardiomyopathy. We will discuss the current clinical measures that are used to monitor patients, the limitations of each technique, and then detail research into novel methods for tracking and detecting the cardiac toxicity and cardiac dysfunction that may occur as a result of chemotherapy.
authors.affiliation: Department of Medicine, Division of Cardiology, Cardio-Oncology Program, Massachusetts General Hospital, Boston, MA 02114, USA.
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Ong
authors.forename: Marielle
authors.initials: M
authors.lastname: Scherrer-Crosbie
authors.forename: Otavio
authors.initials: O
authors.lastname: Coelho-Filho
authors.forename: Sanjeev A
authors.initials: SA
authors.lastname: Francis
authors.forename: Tomas G
authors.initials: TG
authors.lastname: Neilan
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D066126:Cardiotoxicity / Q000175:diagnosis*; D006331:Heart Diseases / Q000139:chemically induced / Q000188:drug therapy*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000401:mortality
chemical_list: D000970:Antineoplastic Agents