title: Evaluation of serum CA 125 level and its relation to surgical, histopathologic and ultrasonographic findings in patients with pelvic mass.
abstract: OBJECTIVE
  The aim of this study was to determine the relationship between the levels of tumour marker CA 125 antigen and pelvic tumour size, histopathological type, stage, bilateral status, ascites, type of surgery, and postoperative complications.
  
  
  METHODS
  A retrospective cross-sectional descriptive study was conducted on 203 patients with a pelvic mass who were visited in the Shahid Sadoughi hospital in Yazd, Iran from 2007 to 2010. Data were analyzed by software SPSS v.14.
  
  
  RESULTS
  Statistical analysis, based on Fisher's exact test, showed that patients with pelvic mass who presented with either of bilateral involvement/ascites (p = 0.000), higher stage (p = 0.001), inability for complete resection (p = 0.000), or postoperative complications (p = 0.001) had significantly higher serum concentrations of CA 125 antigen. There was no relationship between serum level of CA 125 and such variables as tumor size (p = 0.883) and abdominal ultrasound findings (p = 0.297).
  
  
  CONCLUSIONS
  Using CA 125 as a diagnostic and prognostic tool in patients with newly-discovered pelvic mass can be helpful in some aspects, but cannot estimate size of the tumor and its solid/cystic status. It also cannot predict post-surgical complications of malignant pelvic masses.
authors.forename: M
authors.initials: M
authors.lastname: Karimi-Zarchi
authors.forename: Ahmadpour
authors.initials: A
authors.lastname: Baghdadabad
authors.forename: M R Ahmadpour
authors.initials: MR
authors.lastname: Baghdadabad
authors.forename: Sh Taghipour
authors.initials: ShT
authors.lastname: Zahir
authors.forename: R Deghani Firooz
authors.initials: RD
authors.lastname: Abadi
authors.forename: S
authors.initials: S
authors.lastname: Teimoori
authors.forename: Z
authors.initials: Z
authors.lastname: Chiti
authors.forename: S
authors.initials: S
authors.lastname: Hekmatimoghaddam
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018394:CA-125 Antigen / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007492:Iran; D008875:Middle Aged; D010386:Pelvic Neoplasms / Q000097:blood* / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D011183:Postoperative Complications; D012189:Retrospective Studies; D016019:Survival Analysis; D014463:Ultrasonography; D055815:Young Adult
chemical_list: D018394:CA-125 Antigen