title: Impact of bacterial culture positivity of the drainage fluid during the early postoperative period on the development of intra-abdominal abscesses after gastrectomy.
abstract: OBJECTIVE
  The aim of this study was to evaluate the impact of positive bacterial cultures of the drainage fluid (D-cultures) during the early postoperative period on the incidence of intra-abdominal abscess formation following gastrectomy.
  
  
  METHODS
  From January 2012 to June 2013, we prospectively performed D-cultures on postoperative day (POD) 1 in consecutive gastric cancer patients who underwent gastrectomy. The univariate and multivariate analyses were performed to identify the risk factors for intra-abdominal abscess formation without anastomotic leakage.
  
  
  RESULTS
  The rate of positive D-cultures was 6.4 % on POD 1. According to a univariate analysis, the use of combined organ resection (P = 0.011), the drain amylase level on POD 1 (P = 0.016) and the D-culture status on POD 1 (P = 0.004) were found to be significantly associated with the incidence of intra-abdominal abscesses. A multivariate analysis demonstrated that D-culture positivity on POD 1 was the only independent predictor of intra-abdominal abscess formation (P = 0.011).
  
  
  CONCLUSIONS
  The present study demonstrated that bacterial culture positivity of drainage fluid during the early postoperative period has a significant impact on the development of intra-abdominal abscesses after gastrectomy.
authors.affiliation: Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan, kmigita@naramed-u.ac.jp.
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Migita
authors.forename: Tomoyoshi
authors.initials: T
authors.lastname: Takayama
authors.forename: Sohei
authors.initials: S
authors.lastname: Matsumoto
authors.forename: Kohei
authors.initials: K
authors.lastname: Wakatsuki
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Tanaka
authors.forename: Masahiro
authors.initials: M
authors.lastname: Ito
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Nakajima
mesh_terms: D018784:Abdominal Abscess / Q000453:epidemiology / Q000382:microbiology*; D000368:Aged; D000681:Amylases / Q000378:metabolism; D057868:Anastomotic Leak; D001419:Bacteria / Q000302:isolation & purification*; D001431:Bacteriological Techniques; D001826:Body Fluids / Q000201:enzymology / Q000382:microbiology*; D004322:Drainage; D005260:Female; D005743:Gastrectomy; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011183:Postoperative Complications / Q000453:epidemiology / Q000382:microbiology*; D011184:Postoperative Period; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000601:surgery
chemical_list: D000681:Amylases