title: A case report of seronegative cat scratch disease, emphasizing the histopathologic point of view.
abstract: Cat scratch disease, necrotizing granulomatous lymphadenitis caused by Bartonella henselae, usually benign and self-limited. However, various clinical manifestations and no pathognomonic histopathologic features can lead to misinterpretations and diagnostic disputes. We report a case of cat scratch disease in a 39-yr-old male patient with fever and left axillary lymphadenitis. He had a history of cat bite on the left hand dorsum. On excision, the lymph node showed follicular hyperplasia, stellate microabscesses with a rim of granulomatous inflammation. Warthin-Starry silver staining showed many clumps of silver-stained bacilli within the necrotic foci. Serological tests were negative. Diagnosis was established by PCR analysis.
  The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1877499238123059.
authors.forename: Ok Ran
authors.initials: OR
authors.lastname: Shin
authors.forename: Yang Ree
authors.initials: YR
authors.lastname: Kim
authors.forename: Tae-hyun
authors.initials: TH
authors.lastname: Ban
authors.forename: Taeseok
authors.initials: T
authors.lastname: Lim
authors.forename: Tae Hee
authors.initials: TH
authors.lastname: Han
authors.forename: Su Yeon
authors.initials: SY
authors.lastname: Kim
authors.affiliation: Department of Hospital Pathology, Uijeongbu St, Mary's Hospital College of Medicine, The Catholic University of Korea 271, Cheonbo-ro, Uijeongbu-si, Gyenggi-do 480-717, Republic of Korea. ywacko@catholic.ac.kr.
authors.forename: Kyung Jin
authors.initials: KJ
authors.lastname: Seo
mesh_terms: D000328:Adult; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D018416:Bartonella henselae / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D015415:Biomarkers / Q000097:blood; D001706:Biopsy; D002372:Cat-Scratch Disease / Q000097:blood / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology / Q000635:transmission; D002415:Cats; D004269:DNA, Bacterial / Q000302:isolation & purification; D006801:Humans; D008198:Lymph Nodes / Q000276:immunology / Q000382:microbiology* / Q000473:pathology; D008297:Male; D016133:Polymerase Chain Reaction; D011237:Predictive Value of Tests; D012698:Serologic Tests
chemical_list: D000907:Antibodies, Bacterial; D015415:Biomarkers; D004269:DNA, Bacterial