title: Macrophage activation syndrome in Kawasaki disease.
abstract: BACKGROUND
  Kawasaki disease is an acute febrile vasculitis of childhood. Macrophage activation syndrome is a rare life threatening complication.
  
  
  METHODS
  4-year-old boy with Kawasaki Disease treated with intravenous immunoglobulins.
  
  
  METHODS
  He developed encephalopathy, hepatosplenomegaly and pancytopenia. Blood investigations and bone marrow aspiration suggested macrophage activation syndrome.
  
  
  RESULTS
  Good response to pulse methylprednisolone (30 mg/kg/d) for 5 days.
  
  
  CONCLUSIONS
  Macrophage activation syndrome may complicate Kawasaki disease.
authors.affiliation: Departments of Pediatric Medicine and Pediatric Rheumatology, Institute of Child Health, Kolkata, West Bengal, India. Correspondence to: Dr Devdeep Mukherjee, Flat No. 6F, Uttara Co-operative Housing Society, 13, Broad Street, Kolkata - 700019. devdeep_dm@rediffmail.com.
authors.forename: Devdeep
authors.initials: D
authors.lastname: Mukherjee
authors.forename: Priyankar
authors.initials: P
authors.lastname: Pal
authors.forename: Ritabrata
authors.initials: R
authors.lastname: Kundu
authors.forename: Prabal
authors.initials: P
authors.lastname: Niyogi
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002675:Child, Preschool; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D055501:Macrophage Activation Syndrome / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications* / Q000188:drug therapy
chemical_list: D000893:Anti-Inflammatory Agents; D016756:Immunoglobulins, Intravenous; D008775:Methylprednisolone