title: Three new flavonol glycosides from Suaeda maritima.
abstract: Three new flavonol glycosides isolated from the 70% methanol extract of Suaeda maritima (Chenopodiaceae) were characterized based on spectroscopic and chemical methods as quercetin 3-O-α-l-rhamnopyranosyl(1″' → 6″)-β-d-galactopyranoside-7-O-β-d-glucopyranosyl(1″″' → 2″″)-glucopyranoside, kaempferol 3-O-α-l-rhamnopyranosyl(1″' → 6″)-β-d-galactopyranoside-7-O-β-d-glucopyranosyl(1″″' → 2″″)-glucopyranoside, and kaempferol 3-O-α-l-rhamnopyranosyl(1″' → 6″)-β-d-galactopyranoside-7-O-(2″″'-O-trans-feruloyl)-β-d-glucopyranosyl-(1″″' → 2″″)-β-d-glucopyranoside. In addition, four known compounds, namely, quercetin and kaempferol, methyl cis, trans-ferulate, and methyl trans-ferulate were identified. The plant extract and these compounds showed cytotoxic activity against the human tumor cell lines MCF7, HCT116, and HEPG2.
authors.affiliation: a Phytochemistry and Plant Systematics Department, National Research Center , Dokki 12311 , Giza , Egypt.
authors.forename: Rasha R
authors.initials: RR
authors.lastname: Abd El-Latif
authors.forename: Ragaa M A
authors.initials: RM
authors.lastname: Mansour
authors.forename: Mohamed
authors.initials: M
authors.lastname: Sharaf
authors.forename: Ahmad
authors.initials: A
authors.lastname: Farag
mesh_terms: D000972:Antineoplastic Agents, Phytogenic; D019663:Chenopodiaceae / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D005260:Female; D044948:Flavonols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045325:HCT116 Cells; D056945:Hep G2 Cells; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013237:Stereoisomerism
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D044948:Flavonols; D006027:Glycosides
keywords: Chenopodiaceae; Suaeda maritime; biological study; flavonol polyglycosides