title: Efficacy of telmisartan and atenolol in management of essential hypertension.
abstract: BACKGROUND
  Telmisartan and atenolol are widely used in the management of essential hypertension. This study was conducted to compare the efficacy of these two drugs in management of patients of essential hypertension.
  
  
  METHODS
  Diagnosed patients of essential hypertension were selected. Therapeutic option (telmisartan/atenolol) was allocated to the patients by lottery method and they were divided into two groups. The patients were followed on subsequent visits (4 in total) and their sitting systolic and diastolic blood pressures were recorded.
  
  
  RESULTS
  Total number of 180 patients were divided into two treatment groups (i.e., telmisaran and atenolol). Forty percent were male and 60% were female. Majority of the patients were of age group 56-75 years. Telmisartan reduced systolic and diastolic blood pressure significantly compared to atenolol at the end of 8 weeks of treatment (p = 0.000 and 0.016 respectively).
  
  
  CONCLUSIONS
  Telmisartan 80 mg once daily is more effective than atenolol 50 mg once daily in lowering systolic and diastolic blood pressure at the end of 8 weeks of treatment.
authors.forename: Purdil
authors.initials: P
authors.lastname: Khan
authors.forename: Wasil
authors.initials: W
authors.lastname: Khan
authors.forename: Abdullah
authors.initials: A
authors.lastname: Abbasi
authors.forename: A
authors.initials: A
authors.lastname: Ahad
authors.forename: Momin
authors.initials: M
authors.lastname: Khan
authors.forename: Yasir
authors.initials: Y
authors.lastname: Ahmad
authors.forename: Aziz
authors.initials: A
authors.lastname: Ahmad
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001262:Atenolol / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use*; D001565:Benzoates / Q000627:therapeutic use*; D000075222:Essential Hypertension; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D000077333:Telmisartan; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents; D001562:Benzimidazoles; D001565:Benzoates; D001262:Atenolol; D000077333:Telmisartan