title: A Power-Efficient Wireless System With Adaptive Supply Control for Deep Brain Stimulation.
abstract: A power-efficient wireless stimulating system for a head-mounted deep brain stimulator (DBS) is presented. A new adaptive rectifier generates a variable DC supply voltage from a constant AC power carrier utilizing phase control feedback, while achieving high AC-DC power conversion efficiency (PCE) through active synchronous switching. A current-controlled stimulator adopts closed-loop supply control to automatically adjust the stimulation compliance voltage by detecting stimulation site potentials through a voltage readout channel, and improve the stimulation efficiency. The stimulator also utilizes closed-loop active charge balancing to maintain the residual charge at each site within a safe limit, while receiving the stimulation parameters wirelessly from the amplitude-shift-keyed power carrier. A 4-ch wireless stimulating system prototype was fabricated in a 0.5-μm 3M2P standard CMOS process, occupying 2.25 mm². With 5 V peak AC input at 2 MHz, the adaptive rectifier provides an adjustable DC output between 2.5 V and 4.6 V at 2.8 mA loading, resulting in measured PCE of 72 ~ 87%. The adaptive supply control increases the stimulation efficiency up to 30% higher than a fixed supply voltage to 58 ~ 68%. The prototype wireless stimulating system was verifiedin vitro.
authors.affiliation: School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30308 USA.
authors.forename: Hyung-Min
authors.initials: HM
authors.lastname: Lee
authors.affiliation: School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30308 USA.
authors.forename: Hangue
authors.initials: H
authors.lastname: Park
authors.affiliation: School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30308 USA.
authors.forename: Maysam
authors.initials: M
authors.lastname: Ghovanloo
keywords: Active charge balancing; adaptive rectifier; closed-loop supply control; head-mounted deep brain stimulation; implantable medical devices; inductive power transfer