title: A neonatal case of chronic granulomatous disease, initially presented with invasive pulmonary aspergillosis.
abstract: Chronic granulomatous disease (CGD) often presents with infectious illness, such as repeating bacterial and fungal infections, due to the inability to generate superoxide, which would destroy certain infectious pathogens, and is usually diagnosed in childhood. We describe a CGD case diagnosed in neonatal period, who initially presented with invasive aspergillosis. Neonatal invasive pulmonary aspergillosis is very rare and, to the best of our knowledge, this might be the youngest case in Japan.
authors.affiliation: Department of Pediatrics, Nagano Children's Hospital, Azumino, Japan.
authors.forename: Sachiko
authors.initials: S
authors.lastname: Saito
authors.affiliation: Department of Pediatrics, Nagano Children's Hospital, Azumino, Japan.
authors.forename: Arata
authors.initials: A
authors.lastname: Oda
authors.affiliation: Department of Pediatrics, Nagano Children's Hospital, Azumino, Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Kasai
authors.affiliation: Department of Pediatrics, Nagano Children's Hospital, Azumino, Japan. Electronic address: kiseiminami@gmail.com.
authors.forename: Kisei
authors.initials: K
authors.lastname: Minami
authors.affiliation: Department of Pediatrics, Nagano Children's Hospital, Azumino, Japan.
authors.forename: Haruo
authors.initials: H
authors.lastname: Nagumo
authors.affiliation: Department of Pediatrics, Nagano Children's Hospital, Azumino, Japan.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Shiohara
authors.affiliation: Department of Pediatrics, Nagano Children's Hospital, Azumino, Japan.
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Ogiso
authors.affiliation: Division of Infection Control and Biological Regulations, Department of Health and Medical Sciences, Shinshu University Graduate School of Medicine, Matsumoto, Japan.
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Kawakami
mesh_terms: D000367:Age Factors; D000935:Antifungal Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006105:Granulomatous Disease, Chronic / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D007231:Infant, Newborn; D055744:Invasive Pulmonary Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000935:Antifungal Agents
keywords: Chronic granulomatous disease; Invasive aspergillosis; Neonate