title: Balloon valvuloplasty as a treatment of congenital aortic stenosis in children and adolescents.
abstract: BACKGROUND
  Balloon valvuloplasty (BVP) is one of the primary therapies for congenital aortic stenosis in children and adolescents. The aim of this interventional procedure is to gain time before possible surgical therapy (aortic valve replacement) until adulthood.
  
  
  OBJECTIVE
  The aim of this study was to evaluate the efficacy, safety and mid-term results oftranscatheter BVP in children and adolescent in our Center.
  
  
  METHODS
  From 2004 to 2011, 50 patients, aged 18 days to 18 years (mean 6.3 years) underwent BVP. Retrospective analysis of the echocardiographic and hemodynamic parameters were performed before and after procedure, especially peak pressure gradient (PG) across the aortic valve, semiquantification of the aortic regurgitation (AR) after the BVP as well as the left ventricle dimensions and functions.
  
  
  RESULTS
  The mean peak PG in the whole group decreased from 74.80 +/- 27.72 mm Hg to 27.86 +/- 3.04 mm Hg (p < 0.001) after BVP. In 39 patients (78%), residual PG was lower than 30 mm Hg just after dilation. At the end of follow-up period, 25 patients (50%) had PG above 50 mm Hg, measured by Doppler technique, and four of them underwent re-dilation. Eight patients (16%) had severe AR. During the follow-up period (12-80 months, mean 51 months), six patients (12%) were referred to cardiac surgeons for aortic valve replacement or Ross procedure.
  
  
  CONCLUSIONS
  This retrospective study analyzes our first experience of BVP as primary therapy of the congenital aortic stenosis. The results confirmed that BVP effectively postponed the need for surgery in children and adolescents toward the adulthood.
authors.forename: Vojislav
authors.initials: V
authors.lastname: Parezanović
authors.forename: Milan
authors.initials: M
authors.lastname: Djukić
authors.forename: Ingo
authors.initials: I
authors.lastname: Daehnert
authors.forename: Ana
authors.initials: A
authors.lastname: Gligić
authors.forename: Igor
authors.initials: I
authors.lastname: Stefanović
authors.forename: Ida
authors.initials: I
authors.lastname: Jovanović
authors.forename: Tamara
authors.initials: T
authors.lastname: Ilisić
authors.forename: Slobodan
authors.initials: S
authors.lastname: Ilić
authors.forename: Irena
authors.initials: I
authors.lastname: Vulićević
authors.forename: Jasna
authors.initials: J
authors.lastname: Kalanj
mesh_terms: D000293:Adolescent; D001021:Aortic Valve / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging*; D001024:Aortic Valve Stenosis / Q000151:congenital / Q000000981:diagnostic imaging / Q000601:surgery*; D063126:Balloon Valvuloplasty / Q000379:methods*; D002404:Catheterization; D002648:Child; D002675:Child, Preschool; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006439:Hemodynamics; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011183:Postoperative Complications / Q000000981:diagnostic imaging*; D012086:Reoperation; D012189:Retrospective Studies; D014463:Ultrasonography