title: Outbreak of AmpC β-lactamase-hyper-producing Enterobacter cloacae in a neonatal intensive care unit in a French teaching hospital.
abstract: We report the investigation of an outbreak of colonization by a wild-type Enterobacter cloacae and its AmpC-hyper-producing derivative E cloacae in a neonatal intensive care unit. E cloacae hyper-producing AmpC β-lactamase isolates were found from neonate specimens and from environmental samples. All the isolates belonged to the same clone.
authors.affiliation: INSERM, U1092, Limoges, France; Université de Limoges, UMR-S1092, Faculté de Médecine, Limoges, France; Laboratoire de Bactériologie-Virologie-Hygiène, CHU Limoges, Limoges, France.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Pestourie
authors.affiliation: INSERM, U1092, Limoges, France; Université de Limoges, UMR-S1092, Faculté de Médecine, Limoges, France; Laboratoire de Bactériologie-Virologie-Hygiène, CHU Limoges, Limoges, France.
authors.forename: Fabien
authors.initials: F
authors.lastname: Garnier
authors.affiliation: INSERM, U1092, Limoges, France; Université de Limoges, UMR-S1092, Faculté de Médecine, Limoges, France; Laboratoire de Bactériologie-Virologie-Hygiène, CHU Limoges, Limoges, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Barraud
authors.affiliation: Service de Réanimation Nénonatale, CHU Limoges, Limoges, France.
authors.forename: Antoine
authors.initials: A
authors.lastname: Bedu
authors.affiliation: INSERM, U1092, Limoges, France; Université de Limoges, UMR-S1092, Faculté de Médecine, Limoges, France; Laboratoire de Bactériologie-Virologie-Hygiène, CHU Limoges, Limoges, France. Electronic address: marie-cecile.ploy@unilim.fr.
authors.forename: Marie-Cécile
authors.initials: MC
authors.lastname: Ploy
authors.affiliation: INSERM, U1092, Limoges, France; Université de Limoges, UMR-S1092, Faculté de Médecine, Limoges, France; Laboratoire de Bactériologie-Virologie-Hygiène, CHU Limoges, Limoges, France.
authors.forename: Marcelle
authors.initials: M
authors.lastname: Mounier
mesh_terms: D001426:Bacterial Proteins / Q000378:metabolism*; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D004196:Disease Outbreaks; D016521:Electrophoresis, Gel, Pulsed-Field; D016972:Enterobacter cloacae / Q000145:classification / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000453:epidemiology / Q000382:microbiology*; D004783:Environmental Microbiology; D005260:Female; D005602:France / Q000453:epidemiology; D005838:Genotype; D006784:Hospitals, Teaching; D006801:Humans; D007231:Infant, Newborn; D015931:Intensive Care, Neonatal; D008297:Male; D017720:Molecular Epidemiology; D058889:Molecular Typing; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; C048795:AmpC beta-lactamases; D001618:beta-Lactamases
keywords: Breast-feeding; Cross transmission; Pulsed-field electrophoresis