title: Autoamplification of molecular chirality through the induction of supramolecular chirality.
abstract: The novel concept for the autoamplification of molecular chirality, wherein the amplification proceeds through the induction of supramolecular chirality, is presented. A solution of prochiral, ring-open diarylethenes is doped with a small amount of their chiral, ring-closed counterpart. The molecules co-assemble into helical fibers through hydrogen bonding and the handedness of the fibers is biased by the chiral, ring-closed diarylethene. Photochemical ring closure of the open diarylethene yields the ring-closed product, which is enriched in the template enantiomer.
authors.affiliation: Center for Systems Chemistry, Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen (The Netherlands).
authors.forename: Derk Jan
authors.initials: DJ
authors.lastname: van Dijken
authors.forename: John M
authors.initials: JM
authors.lastname: Beierle
authors.forename: Marc C A
authors.initials: MC
authors.lastname: Stuart
authors.forename: Wiktor
authors.initials: W
authors.lastname: Szymański
authors.forename: Wesley R
authors.initials: WR
authors.lastname: Browne
authors.forename: Ben L
authors.initials: BL
authors.lastname: Feringa
mesh_terms: D020285:Cryoelectron Microscopy; D046529:Microscopy, Electron, Transmission; D008968:Molecular Conformation; D013056:Spectrophotometry, Ultraviolet; D013237:Stereoisomerism
keywords: chirality; gels; hydrogen bonds; self-assembly; supramolecular chemistry