title: [1, 2, 4]-oxadiazoles: synthesis and biological applications.
abstract: In the present article synthesis and medicinal applications of [1, 2, 4] oxadiazoles are reviewed. The oxadiazoles have a wide range of applications such as Antitussive, Anti-inflammatory, Anaesthetic, Vasodilator, anthelmintic, antiallergic, antiplatelet effects in vitro, antithrombotic properties in vivo, etc. Many researchers have synthesized novel heterocyclic compounds containing oxadiazoles with the concept of bioisosterism.
authors.forename: Rajesh O
authors.initials: RO
authors.lastname: Bora
authors.forename: Bashir
authors.initials: B
authors.lastname: Dar
authors.forename: Vidya
authors.initials: V
authors.lastname: Pradhan
authors.affiliation: Post Graduate and Research centre, Maulana Azad College, Aurangabad, and Indian Institute of Integrative Medicine Jammu 180001. mazahar_64@rediffmail.com.
authors.forename: Mazahar
authors.initials: M
authors.lastname: Farooqui
mesh_terms: D000777:Anesthetics / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000633:toxicity; D017209:Apoptosis / Q000187:drug effects; D001792:Blood Platelets / Q000187:drug effects; D005343:Fibrinolytic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use; D006967:Hypersensitivity / Q000188:drug therapy; D010069:Oxadiazoles / Q000737:chemistry* / Q000494:pharmacology / Q000627:therapeutic use; D010975:Platelet Aggregation Inhibitors / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D014665:Vasodilator Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use; D020246:Venous Thrombosis / Q000188:drug therapy
chemical_list: D000777:Anesthetics; D000893:Anti-Inflammatory Agents; D000970:Antineoplastic Agents; D005343:Fibrinolytic Agents; D010069:Oxadiazoles; D010975:Platelet Aggregation Inhibitors; D014665:Vasodilator Agents