title: Epidemiology, outcomes and validation of RIFLE and AKIN criteria in acute kidney injury (AKI) in critically ill patients: Indian perspective.
abstract: Although the epidemiology and the impact of Acute Kidney Injury on outcomes are well-known in the Western literature, good data is lacking from India. Most studies published from India have not evaluated epidemiology of Acute Kidney Injury in the Intensive Care Unit setting and/or have not used validated criteria. In our observational study of 250 patients, admitted to a tertiary level ICU, we have explored the epidemiology of Acute Kidney Injury using both RIFLE and AKIN criteria and have validated them. We have also demonstrated that the severity of AKI is an independent predictor of mortality in critically ill patients. Our results are very much comparable to other studies and we feel that this study will remain as an epidemiological reference point for Indian clinicians dealing with AKI.
authors.affiliation: Department of Critical Care Medicine , Apollo Hospitals, Chennai , India and.
authors.forename: N Pavan Kumar
authors.initials: NP
authors.lastname: Reddy
authors.forename: K P
authors.initials: KP
authors.lastname: Ravi
authors.forename: P
authors.initials: P
authors.lastname: Dhanalakshmi
authors.forename: Rajeev
authors.initials: R
authors.lastname: Annigeri
authors.forename: Nagarajan
authors.initials: N
authors.lastname: Ramakrishnan
authors.forename: Ramesh
authors.initials: R
authors.lastname: Venkataraman
mesh_terms: D058186:Acute Kidney Injury / Q000401:mortality*; D000328:Adult; D000368:Aged; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007362:Intensive Care Units / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012720:Severity of Illness Index; D055815:Young Adult
keywords: AKIN; Acute kidney injury; RIFLE; dialysis; epidemiology