title: Epithelioid sarcoma of the spine: case report and literature review.
abstract: Epithelioid sarcomas are rare mesenchymal neoplasms mainly arising in the limbs of young adults. We report the case of a 24-year-old male presenting low back pain radiating to both lower limbs, constipation and urinary retention. The MRI scan showed an intraspinal lesion extending from L4 to S2. Surgery resulted in gross total removal of the extradural lesion and partial removal of the intradural component. The immunohistological study of the lesion was consistent with an epithelioid sarcoma. The patient was submitted to radiotherapy and chemotherapy, but a local recurrence of the lesion and dissemination along the neuraxis were observed 3 months after surgery. Despite treatment, the patient died 4 months after the surgical procedure due to multiorgan failure. Despite there being isolated reports of epithelioid sarcomas appearing in the spine, this is, to our knowledge, the first case with intradural extension.
authors.affiliation: Servicio de Neurocirugía, Hospital São João, Porto. Portugal. Electronic address: clarachamadoira@gmail.com.
authors.forename: Clara
authors.initials: C
authors.lastname: Chamadoira
authors.affiliation: Servicio de Neurocirugía, Hospital São João, Porto. Portugal.
authors.forename: Paulo
authors.initials: P
authors.lastname: Pereira
authors.affiliation: Servicio de Neurocirugía, Hospital São João, Porto. Portugal.
authors.forename: Pedro S
authors.initials: PS
authors.lastname: Silva
authors.affiliation: Servicio de Anatomía Patológica, Hospital São João, Porto. Portugal.
authors.forename: Ligia
authors.initials: L
authors.lastname: Castro
authors.affiliation: Servicio de Neurocirugía, Hospital São João, Porto. Portugal.
authors.forename: Rui
authors.initials: R
authors.lastname: Vaz
mesh_terms: D006801:Humans; D008297:Male; D012509:Sarcoma / Q000175:diagnosis / Q000628:therapy; D013125:Spinal Neoplasms / Q000175:diagnosis / Q000628:therapy; D055815:Young Adult
keywords: Columna vertebral; Dura mater; Duramadre; Epithelioid sarcoma; Immunohistochemistry; Inmunohistoquímica; Sarcoma epitelioide; Spine