title: Thiazolidinones derived from dynamic systemic resolution of complex reversible-reaction networks.
abstract: A complex dynamic system based on a network of multiple reversible reactions has been established. The network was applied to a dynamic systemic resolution protocol based on kinetically controlled lipase-catalyzed transformations. This resulted in the formation of cyclized products, where two thiazolidinone compounds were efficiently produced from a range of potential transformations.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Olof
authors.initials: O
authors.lastname: Ramström
mesh_terms: D003500:Cyclization; D007700:Kinetics; D008049:Lipase / Q000737:chemistry*; D056004:Molecular Dynamics Simulation; D015394:Molecular Structure; D013237:Stereoisomerism; D013816:Thermodynamics; D045162:Thiazolidinediones / Q000737:chemistry*
chemical_list: D045162:Thiazolidinediones; D008049:Lipase