title: Safety measurements for heating of instruments for cardiovascular interventions in magnetic particle imaging (MPI) - first experiences.
abstract: Magnetic particle imaging (MPI) has emerged as a new imaging method with the potential of delivering images of high spatial and temporal resolutions and free of ionizing radiation. Recent studies demonstrated the feasibility of differentiation between signal-generating and non-signal-generating devices in Magnetic Particle Spectroscopy (MPS) and visualization of commercially available catheters and guide-wires in MPI itself. Thus, MPI seems to be a promising imaging tool for cardiovascular interventions. Several commercially available catheters and guide-wires were tested in this study regarding heating. Heating behavior was correlated to the spectra generated by the devices and measured by the MPI. The results indicate that each instrument should be tested separately due to the wide spectrum of measured temperature changes of signal-generating instruments, which is up to 85°C in contrast to non-signal-generating devices. Development of higher temperatures seems to be a limitation for the use of these devices in cardiovascular interventions.
authors.affiliation: Department of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Luebeck, Germany.
authors.forename: Robert L
authors.initials: RL
authors.lastname: Duschka
authors.affiliation: Institute of Medical Engineering, University of Luebeck, Luebeck, Germany.
authors.forename: Hanne
authors.initials: H
authors.lastname: Wojtczyk
authors.affiliation: Department of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Luebeck, Germany.
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Panagiotopoulos
authors.affiliation: Department of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Luebeck, Germany.
authors.forename: Julian
authors.initials: J
authors.lastname: Haegele
authors.affiliation: Institute of Medical Engineering, University of Luebeck, Luebeck, Germany.
authors.forename: Gael
authors.initials: G
authors.lastname: Bringout
authors.affiliation: Institute of Medical Engineering, University of Luebeck, Luebeck, Germany.
authors.forename: Thorsten M
authors.initials: TM
authors.lastname: Buzug
authors.affiliation: Department of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Luebeck, Germany.
authors.forename: Joerg
authors.initials: J
authors.lastname: Barkhausen
authors.affiliation: Department of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Luebeck, Germany.
authors.forename: Florian M
authors.initials: FM
authors.lastname: Vogt
mesh_terms: D006328:Cardiac Catheterization; D062906:Cardiac Catheters; D002318:Cardiovascular Diseases / Q000175:diagnosis* / Q000473:pathology*; D003952:Diagnostic Imaging / Q000379:methods*; D004867:Equipment Design; D005290:Ferric Compounds / Q000737:chemistry; D006358:Hot Temperature; D006801:Humans; D008280:Magnetics; D053768:Metal Nanoparticles / Q000737:chemistry; D055100:Optical Fibers; D009991:Oscillometry; D061214:Patient Safety; D019047:Phantoms, Imaging; D013997:Time Factors
chemical_list: D005290:Ferric Compounds; C000499:ferric oxide
keywords: cardiovascular intervention; interventional devices; magnetic field; magnetic particle imaging (mpi); safety aspects and heating