title: Environmentally benign synthesis and antimicrobial study of novel chalcogenophosphates.
abstract: We report in this work an environmentally benign zinc mediated synthesis of aryl and benzyl phosphorochalcogenoates in ethanol within a short reaction time. In vitro antimicrobial study along with statistical analysis and seed germination assay were performed. These chalcogenophosphates possess strong antimicrobial activity against the reference strains. The antibacterial activity was determined against four standard strains (Bacilus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa). The antifungal activity was evaluated against one fungal strain Candida albicans.
authors.affiliation: Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India.
authors.forename: Shubhanjan
authors.initials: S
authors.lastname: Mitra
authors.affiliation: Department of Botany, Visva-Bharati (A Central University), Santiniketan 731235, India.
authors.forename: Sayani
authors.initials: S
authors.lastname: Mukherjee
authors.affiliation: Department of Botany, Visva-Bharati (A Central University), Santiniketan 731235, India.
authors.forename: Sukanta K
authors.initials: SK
authors.lastname: Sen
authors.affiliation: Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India. Electronic address: alakananda.hajra@visva-bharati.ac.in.
authors.forename: Alakananda
authors.initials: A
authors.lastname: Hajra
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy; D002176:Candida albicans / Q000187:drug effects; D002177:Candidiasis / Q000188:drug therapy; D018011:Chalcogens / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D055772:Green Chemistry Technology; D006801:Humans; D008826:Microbial Sensitivity Tests; D010710:Phosphates / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000890:Anti-Infective Agents; D018011:Chalcogens; D010710:Phosphates
keywords: Antimicrobial activity; Chalcogenophosphate; Green synthesis; Seed germination assay; Statistical analysis