title: Multiple sclerosis and pregnancy.
abstract: The question of pregnancy in patients with multiple sclerosis is regularly raised due to the prevalence of the disease in middle age women. The multiple sclerosis think tank (Groupe de Réflexion sur la Sclérose en Plaques [GRESEP]) decided to develop recommendations on this issue, with consideration to both the impact of multiple sclerosis on pregnancy, and that of pregnancy on the disease. As with topics of previous works, the formal expert consensus method was used. The working group was composed of hospital-based and private practice neurologists. The reading group was composed of neurologists, anaesthetists and obstetricians. Each recommendation is presented with the relevant level of consensus.
authors.affiliation: Hôpital européen Georges-Pompidou, AP-HP, 20, rue Leblanc, 75015 Paris, France; Service de neurologie, centre hospitalier Sainte-Anne, 1, rue Cabanis, 75014 Paris, France; Faculté de médecine, université Paris Descartes, Sorbonne Paris Cité, 12, rue de l'École de Médecine, 75270 Paris cedex 06, France. Electronic address: ebodiguel@orange.fr.
authors.forename: E
authors.initials: E
authors.lastname: Bodiguel
authors.affiliation: Service de neurologie, fondation Rothschild, 25, rue Manin, 75019 Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Bensa
authors.affiliation: Inserm U1043, pôle des neurosciences, hôpital Purpan, université Toulouse-3, place du Dr-Baylac, BP 3028, 31024 Toulouse cedex 3, France.
authors.forename: D
authors.initials: D
authors.lastname: Brassat
authors.affiliation: Inserm UMR643, service de neurologie, pavillon Jean-Monnet, hôtel-Dieu, CHU de Nantes, 30, boulevard Jean-Monnet, 44093 Nantes 01, France; Faculté de médecine de Nantes, 1, rue Gaston-Veïl, 44000 Nantes, France.
authors.forename: D
authors.initials: D
authors.lastname: Laplaud
authors.affiliation: CIC-P 0203 Inserm, pôle des neurosciences cliniques, CHU Pontchaillou, pavillon Clemenceau, 2, rue Henri-Le-Guilloux, 35033 Rennes cedex 9, France.
authors.forename: E
authors.initials: E
authors.lastname: Le Page
authors.affiliation: Pôle des neurosciences cliniques, université de Bordeaux Segalen, CHU de Bordeaux Pellegrin Tripode, 1, place Amélie-Raba-Léon, 33076 Bordeaux cedex, France.
authors.forename: J-C
authors.initials: JC
authors.lastname: Ouallet
authors.affiliation: Pôle de neurologie, hôpital Roger-Salengro, CHRU de Lille, avenue du Pr-Émile-Laine, 59037 Lille, France.
authors.forename: H
authors.initials: H
authors.lastname: Zephir
authors.affiliation: Service de neurologie, laboratoire d'imagerie et de neurosciences cognitives (LINC), CNRS, centre d'investigation clinique (CIC) de Strasbourg, université de Strasbourg, CHU de Strasbourg, 1, place de l'Hôpital, 67000 Strasbourg, France.
authors.forename: J
authors.initials: J
authors.lastname: De Seze
mesh_terms: D000328:Adult; D000367:Age Factors; D000758:Anesthesia; D032921:Consensus; D000075202:Contraindications; D005260:Female; D006801:Humans; D007155:Immunologic Factors / Q000009:adverse effects / Q000627:therapeutic use; D009103:Multiple Sclerosis / Q000150:complications / Q000188:drug therapy*; D049590:Postpartum Period; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D012008:Recurrence
chemical_list: D007155:Immunologic Factors
keywords: Accouchement; Allaitement; Analgésie péridurale; Breastfeeding; Clinical practice guidelines; Consensus formalisé d’experts; Delivery; Epidural analgesia; Grossesse; Multiple sclerosis; Pregnancy; Rand Ucla appropriateness method; Recommandations de pratique clinique; Sclérose en plaques