title: [Prostate and bladder cancer: detection of disseminated tumor cells in bone marrow].
abstract: The prognosis of prostate and bladder cancer patients is predominantly determined by the detection of distant sites of metastasis. In clinical routine, virtually only lymph node staging is of relevance to determine metastasis. Detection and characterization of disseminated tumor cells in peripheral blood or bone marrow is an additional parameter of prognostic significance. In this article, we will summarize recent progress on the prognostic value of disseminated tumor cells in bone marrow and its translation into routine clinical analysis.
authors.affiliation: Klinik und Poliklinik für Urologie, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Straße 22, 81675, München, Deutschland, roman.nawroth@lrz.tum.de.
authors.forename: R
authors.initials: R
authors.lastname: Nawroth
authors.forename: D
authors.initials: D
authors.lastname: Weckermann
authors.forename: M
authors.initials: M
authors.lastname: Retz
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis / Q000235:genetics; D001853:Bone Marrow / Q000473:pathology; D019046:Bone Marrow Neoplasms / Q000235:genetics / Q000401:mortality / Q000473:pathology* / Q000556:secondary*; D018450:Disease Progression; D006801:Humans; D053538:Keratin-18 / Q000235:genetics; D053554:Keratin-20 / Q000235:genetics; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis / Q000473:pathology; D008297:Male; D025202:Molecular Diagnostic Techniques; D009364:Neoplasm Recurrence, Local / Q000235:genetics / Q000401:mortality / Q000473:pathology; D009367:Neoplasm Staging / Q000379:methods; D011379:Prognosis; D011467:Prostate / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000235:genetics* / Q000401:mortality / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor; D053538:Keratin-18; D053554:Keratin-20