title: Higher risk of complications in odynophagia-associated dysphagia in amyotrophic lateral sclerosis.
abstract: OBJECTIVE
  This investigation aimed to identify associated factors with dysphagia severity in amyotrophic lateral sclerosis (ALS).
  
  
  METHODS
  We performed a cross-sectional study of 49 patients with ALS. All patients underwent fiberoptic endoscopy evaluation of swallowing and answered a verbal questionnaire about swallowing complaints. The patients were divided into groups according to dysphagia severity.
  
  
  RESULTS
  Among the factors analyzed, only odynophagia was associated with moderate or severe dysphagia.
  
  
  CONCLUSIONS
  Odynophagia was associated with moderate and severe dysphagia in ALS and suggests a high risk of pulmonary and nutritional complications.
authors.affiliation: Universidade Estadual de Campinas, Campinas, SP, Brazil.
authors.forename: Karen Fontes
authors.initials: KF
authors.lastname: Luchesi
authors.affiliation: Faculdade de Ciencias Medicas, Universidade Estadual de Campinas, Campinas, SP, Brazil.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kitamura
authors.affiliation: Faculdade de Ciencias Medicas, Universidade Estadual de Campinas, Campinas, SP, Brazil.
authors.forename: Lucia Figueiredo
authors.initials: LF
authors.lastname: Mourão
mesh_terms: D000328:Adult; D017668:Age of Onset; D000690:Amyotrophic Lateral Sclerosis / Q000150:complications* / Q000503:physiopathology; D002637:Chest Pain / Q000209:etiology*; D003430:Cross-Sectional Studies; D003680:Deglutition Disorders / Q000209:etiology* / Q000503:physiopathology; D016099:Endoscopy, Gastrointestinal; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000209:etiology; D008297:Male; D044342:Malnutrition / Q000209:etiology; D008875:Middle Aged; D012044:Regression Analysis; D012307:Risk Factors; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires