title: Efficacy evaluation of antimicrobial drug-releasing polymer matrices.
abstract: To assay in vitro antimicrobial activity of substances such as antibiotics or antiseptics, standard methods both in liquid and on solid media are available. These procedures cannot be adequate for testing antimicrobial-releasing or biocidal polymer systems.This chapter is focused on the description of methods that the authors have developed to evaluate the antimicrobial activity of either antimicrobial agent-releasing polymers or biocidal polymers. These assays can be applied to different types of water-soluble or insoluble polymer matrices.
authors.affiliation: Department of Chemistry, Sapienza University of Rome, P.le Aldo Moro 5, 00185, Rome, Italy, iolanda.francolini@uniroma1.it.
authors.forename: Iolanda
authors.initials: I
authors.lastname: Francolini
authors.forename: Antonella
authors.initials: A
authors.lastname: Piozzi
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Donelli
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D001419:Bacteria / Q000187:drug effects; D001431:Bacteriological Techniques; D008826:Microbial Sensitivity Tests / Q000379:methods*; D011108:Polymers / Q000737:chemistry*; D012995:Solubility
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D011108:Polymers