title: Group-wise cortical correspondence via sulcal curve-constrained entropy minimization.
abstract: We present a novel cortical correspondence method employing group-wise registration in a spherical parametrization space for the use in local cortical thickness analysis in human and non-human primate neuroimaging studies. The proposed method is unbiased registration that estimates a continuous smooth deformation field into an unbiased average space via sulcal curve-constrained entropy minimization using spherical harmonic decomposition of the spherical deformation field. We initialize a correspondence by our pair-wise method that establishes a surface correspondence with a prior template. Since this pair-wise correspondence is biased to the choice of a template, we further improve the correspondence by employing unbiased ensemble entropy minimization across all surfaces, which yields a deformation field onto the iteratively updated unbiased average. The specific entropy metric incorporates two terms: the first focused on optimizing the correspondence of automatically extracted sulcal landmarks and the second on that of sulcal depth maps. We also propose an encoding scheme for spherical deformation via spherical harmonics as well as a novel method to choose an optimal spherical polar coordinate system for the most efficient deformation field estimation. The experimental results show evidence that the proposed method improves the correspondence quality in non-human primate and human subjects as compared to the pair-wise method.
authors.forename: Ilwoo
authors.initials: I
authors.lastname: Lyu
authors.forename: Sun Hyung
authors.initials: SH
authors.lastname: Kim
authors.forename: Joon-Kyung
authors.initials: JK
authors.lastname: Seong
authors.forename: Sang Wook
authors.initials: SW
authors.lastname: Yoo
authors.forename: Alan C
authors.initials: AC
authors.lastname: Evans
authors.forename: Yundi
authors.initials: Y
authors.lastname: Shi
authors.forename: Mar
authors.initials: M
authors.lastname: Sanchez
authors.forename: Marc
authors.initials: M
authors.lastname: Niethammer
authors.forename: Martin A
authors.initials: MA
authors.lastname: Styner
mesh_terms: D000465:Algorithms; D000818:Animals; D002540:Cerebral Cortex / Q000033:anatomy & histology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008251:Macaca; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity