title: Asymptomatic bacteriuria in preadolescent girls.
abstract: BACKGROUND
  The detection of asymptomatic bacteriuria in preadolescent girls may be important due to its effects on subsequent pregnancies.
  
  
  OBJECTIVE
  To describe the prevalence of asymptomatic bacteriuria in preadolescent girls and the value of the nitrite test for screening.
  
  
  METHODS
  Cross-sectional study in girls aged 9 to 13 years. Bacteriuria was defined as the growth of > 100,000 CFU/mL in 2 consecutive urine specimens.
  
  
  RESULTS
  Three hundred and twenty seven girls were included. Asymptomatic bacteriuria was found in 7 girls, so the prevalence was 2.1% (95% CI, 1 to 4.4%). Escherichia coli was the isolated agent in all the cases. Focused interrogatory found history of urinary symptoms in 6 girls. The utility values of the nitrite test were: sensitivity, 1; specificity, 0.9; positive likelihood ratio, 10; and negative predictive value, 1.
  
  
  CONCLUSIONS
  The prevalence of asymptomatic bacteriuria in preadolescent girls in this Mexican study is similar to the one reported internationally; it is reasonable to consider its early detection to avoid its effects on future pregnancies. Nitrite test seems to be good for screening.
authors.affiliation: Departamento de Medicina y Nutrición, Universidad de Guanajuato.
authors.forename: Alejandro E
authors.initials: AE
authors.lastname: Macías
authors.forename: Gloria P
authors.initials: GP
authors.lastname: Trujillo
authors.forename: Luis A
authors.initials: LA
authors.lastname: Dubey
authors.forename: Omar A
authors.initials: OA
authors.lastname: Ramírez
authors.forename: Virginia
authors.initials: V
authors.lastname: Arreguín
authors.forename: Juan M
authors.initials: JM
authors.lastname: Muñoz
authors.forename: Juan H
authors.initials: JH
authors.lastname: Macías
authors.forename: Juan L
authors.initials: JL
authors.lastname: Mosqueda
mesh_terms: D000293:Adolescent; D017668:Age of Onset; D058070:Asymptomatic Diseases; D001437:Bacteriuria / Q000175:diagnosis / Q000453:epidemiology* / Q000652:urine; D002648:Child; D003430:Cross-Sectional Studies; D042241:Early Diagnosis; D004926:Escherichia coli / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000652:urine; D005260:Female; D006801:Humans; D008403:Mass Screening; D009573:Nitrites / Q000652:urine; D009582:Nitrofurantoin / Q000627:therapeutic use; D011237:Predictive Value of Tests; D015995:Prevalence; D011627:Puberty; D011934:Reagent Strips; D017211:Treatment Failure
chemical_list: D009573:Nitrites; D011934:Reagent Strips; D009582:Nitrofurantoin