title: Myopericarditis complicated by pulmonary embolism in an immunocompetent patient with acute cytomegalovirus infection: a case report.
abstract: BACKGROUND
  Primary acute cytomegalovirus infection in immunocompetent patients is common worldwide. Infection is most often asymptomatic or occurs sub-clinically with a self-limited mononucleosis-like syndrome. More rarely, the infection may lead to severe organ complications with pneumonia, myocarditis, pericarditis, colitis and hemolytic anemia. Recent cases of cytomegalovirus-associated thrombosis have also been reported sporadically in the medical literature.
  
  
  METHODS
  We report here a case of simultaneous myopericarditis and pulmonary embolism in a 30-year-old man with no medical history. The patient was not immunocompromised. We discuss the possible role of acute cytomegalovirus infection in the induction of vascular damage and review relevant cases in the literature.
  
  
  CONCLUSIONS
  Thrombosis in patients with acute cytomegalovirus infection may be more frequent than is generally thought. Physicians need to be aware of the possible association between acute cytomegalovirus and thrombosis in immunocompetent patients, especially in the presence of severe systemic infection, as our case illustrates.
authors.affiliation: Department of Infectious Diseases and Internal Medicine, Centre Hospitalier Universitaire d'Angers, 4 rue Larrey, 49933 Angers, Cedex 9, France. ymvandamme@chu-angers.fr.
authors.forename: Yves Marie
authors.initials: YM
authors.lastname: Vandamme
authors.forename: Alexandra
authors.initials: A
authors.lastname: Ducancelle
authors.forename: Loïc
authors.initials: L
authors.lastname: Biere
authors.forename: Nathalie
authors.initials: N
authors.lastname: Viot
authors.forename: Frédéric
authors.initials: F
authors.lastname: Rouleau
authors.forename: Valérie
authors.initials: V
authors.lastname: Delbos
authors.forename: Pierre
authors.initials: P
authors.lastname: Abgueguen
mesh_terms: D000328:Adult; D003586:Cytomegalovirus Infections / Q000150:complications / Q000276:immunology / Q000473:pathology* / Q000821:virology; D006801:Humans; D007121:Immunocompetence; D008297:Male; D010493:Pericarditis / Q000150:complications / Q000276:immunology / Q000473:pathology* / Q000821:virology; D011655:Pulmonary Embolism / Q000150:complications / Q000276:immunology / Q000473:pathology* / Q000821:virology