title: Bereitschaftspotential in remitted paediatric bipolar disorder.
abstract: Bereitschaftspotential (BP) is an anticipatory slow wave in the brain that typically precedes a voluntary motor act and its deficit reflects abnormal motor preparatory processes in the brain. Although BP deficits have been consistently noticed in schizophrenia, similar research in depression has yielded contradictory results; therefore, it is unclear if motor anticipatory processes are actually abnormal in mood disorder. We compared both early and late BP between thirty remitted paediatric bipolar patients (PBD) and thirty matched healthy control group subjects. We did not find any evidence of BP abnormality in PBD, indicating normal motor preparatory processes in this condition. This finding is in agreement with our previous research reporting normal anticipatory slow waves in bipolar subjects. Future research needs to address the specificity of normal anticipatory slow waves in bipolar disorder, compared to other major Psychoses.
authors.affiliation: Central Institute of Psychiatry, Jharkhand, India.
authors.forename: Nandini
authors.initials: N
authors.lastname: Banerjee
authors.affiliation: Central Institute of Psychiatry, Jharkhand, India.
authors.forename: Vinod K
authors.initials: VK
authors.lastname: Sinha
authors.affiliation: Department of Psychology, Ranchi University, Jharkhand, India.
authors.forename: Meera
authors.initials: M
authors.lastname: Jayaswal
authors.affiliation: Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, Canada. Electronic address: pushpal.desarkar@utoronto.ca.
authors.forename: Pushpal
authors.initials: P
authors.lastname: Desarkar
mesh_terms: D000293:Adolescent; D001714:Bipolar Disorder / Q000503:physiopathology*; D016022:Case-Control Studies; D002648:Child; D003265:Contingent Negative Variation; D005260:Female; D006801:Humans; D008297:Male
keywords: Adolescent; Bereitschaftspotential; Bipolar disorder; Child