title: Ligand tuning of single-site manganese-based catalytic antioxidants with dual superoxide dismutase and catalase activity.
abstract: A bio-inspired manganese(ii) complex with a linear pentadentate ligand framework containing soft sulfur donors and an alternating NSNSN binding motif displays excellent dual CAT/SOD-like antioxidant activity with high turnover efficiency and good operation stability in an aqueous environment.
authors.affiliation: Department of Chemistry, Imperial College London, Exhibition Road, South Kensington, London SW7 2AY, UK. g.britovsek@imperial.ac.uk.
authors.forename: Michaela
authors.initials: M
authors.lastname: Grau
authors.forename: Francesco
authors.initials: F
authors.lastname: Rigodanza
authors.forename: Andrew J P
authors.initials: AJ
authors.lastname: White
authors.forename: Antonio
authors.initials: A
authors.lastname: Sorarù
authors.forename: Mauro
authors.initials: M
authors.lastname: Carraro
authors.forename: Marcella
authors.initials: M
authors.lastname: Bonchio
authors.forename: George J P
authors.initials: GJ
authors.lastname: Britovsek
mesh_terms: D000975:Antioxidants / Q000737:chemistry*; D040761:Biomimetic Materials / Q000737:chemistry*; D002374:Catalase / Q000737:chemistry*; D020134:Catalytic Domain; D056831:Coordination Complexes / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry; D008024:Ligands; D008345:Manganese / Q000737:chemistry*; D013482:Superoxide Dismutase / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D000975:Antioxidants; D056831:Coordination Complexes; D008024:Ligands; D014867:Water; D008345:Manganese; D006861:Hydrogen Peroxide; D002374:Catalase; D013482:Superoxide Dismutase