title: Quantum dot tailored to single wall carbon nanotubes: a multifunctional hybrid nanoconstruct for cellular imaging and targeted photothermal therapy.
abstract: Hybrid nanomaterial based on quantum dots and SWCNTs is used for cellular imaging and photothermal therapy. Furthermore, the ligand conjugated hybrid system (FaQd@CNT) enables selective targeting in cancer cells. The imaging capability of quantum dots and the therapeutic potential of SWCNT are available in a single system with cancer targeting property. Heat generated by the system is found to be high enough to destroy cancer cells.
authors.affiliation: Biophotonics and Imaging Laboratory, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum, 695012.
authors.forename: Lakshmi V
authors.initials: LV
authors.lastname: Nair
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Nagaoka
authors.forename: Toru
authors.initials: T
authors.lastname: Maekawa
authors.forename: D
authors.initials: D
authors.lastname: Sakthikumar
authors.forename: Ramapurath S
authors.initials: RS
authors.lastname: Jayasree
mesh_terms: D000818:Animals; D016923:Cell Death; D002460:Cell Line; D045744:Cell Line, Tumor; D002470:Cell Survival; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000379:methods; D061986:MCF-7 Cells; D051379:Mice; D046529:Microscopy, Electron, Transmission; D036103:Nanotechnology; D037742:Nanotubes, Carbon / Q000648:ultrastructure; D010789:Phototherapy / Q000379:methods*; D045663:Quantum Dots / Q000737:chemistry / Q000627:therapeutic use*
chemical_list: D037742:Nanotubes, Carbon
keywords: hybrid nanomaterials; photothermal therapy; quantum dots; single wall carbon nanotube; targeted therapy