title: [Effect of interleukin-1β on expressions of activin A and its related factors in cultured endometrial stromal cells from patients with endometriosis].
abstract: OBJECTIVE
  To study the effect of interleukin-1β (IL-1β) on the expressions activin A, follistatin, and cripto in cultured human endometrial stromal cells (HESCs) form patients with endometriosis.
  
  
  METHODS
  Cultured HESCs were stimulated with 250, 500, and 750pg/ml IL-1β, and the mRNA and protein expressions of activin A, follistatin, and cripto were assayed using real-time reverse transcriptase-polymerase chain reaction and enzyme-linked immunosorbent assay.
  
  
  RESULTS
  IL-1β treatment caused significant dose-dependent increments of the mRNA and protein expressions of activin A and follistatin and of the mRNA expression of cripto in cultured HESCs.
  
  
  CONCLUSIONS
  IL-1β can affect the expressions of activin A, follistatin and cripto in HESCs from patients with endometriosis.
authors.affiliation: Department of Obstetrics and Gynecology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. E-mail: lljzmll@126.com.
authors.forename: Lei
authors.initials: L
authors.lastname: Li
authors.forename: Mubiao
authors.initials: M
authors.lastname: Liu
authors.forename: Fengcheng
authors.initials: F
authors.lastname: Zhu
authors.forename: Ying
authors.initials: Y
authors.lastname: Pan
mesh_terms: D028341:Activins / Q000378:metabolism*; D002478:Cells, Cultured; D004715:Endometriosis / Q000378:metabolism*; D004717:Endometrium / Q000166:cytology; D005260:Female; D006801:Humans; D053583:Interleukin-1beta / Q000494:pharmacology*; D017154:Stromal Cells / Q000187:drug effects* / Q000378:metabolism
chemical_list: D053583:Interleukin-1beta; C422405:activin A; D028341:Activins