title: 18F-FDG PET/CT in tumefactive multiple sclerosis.
abstract: A 35-year-old man underwent contrast-enhanced MRI and F-FDG PET/CT for acute peripheral paresthesia, vision loss, muscle weakness, and difficulty walking. T2-weighted MRI demonstrated multiple bright periventricular supratentorial and infratentorial white matter lesions, including 2 with nodularity. Both nodular lesions showed moderate focal FDG uptake (SUVmax, 6.9 in both cases). Cerebrospinal fluid analysis showed increased levels of immunocytes and oligoclonal antibody bands. A diagnosis of acute onset tumefactive multiple sclerosis was made.
authors.affiliation: From the Departments of *Nuclear Medicine, PET Unit, and †Neurology, Santa Maria della Misericordia Hospital, Rovigo, Italy; and ‡Department of Radiology, University of Southern California, Los Angeles, CA.
authors.forename: Anna Margherita
authors.initials: AM
authors.lastname: Maffione
authors.forename: Lucia
authors.initials: L
authors.lastname: Rampin
authors.forename: Gaia
authors.initials: G
authors.lastname: Grassetto
authors.forename: Roberto
authors.initials: R
authors.lastname: L'Erario
authors.forename: Patrick M
authors.initials: PM
authors.lastname: Colletti
authors.forename: Domenico
authors.initials: D
authors.lastname: Rubello
mesh_terms: D000328:Adult; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D064847:Multimodal Imaging; D009103:Multiple Sclerosis / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18