title: Copper(II) complexes supported by click generated mixed NN, NO, and NS 1,2,3-triazole based ligands and their catalytic activity in azide-alkyne cycloaddition.
abstract: The preparation and characterization of four new copper(ii) complexes supported by click generated mixed NN, NO, and NS 1,2,3-triazoles are reported. The four complexes display a 1 : 2 copper/ligand ratio and give monomeric units in the solid state. Crystal structures demonstrate that depending on the flexibility of the ligand NX (X = O, N, S) pendant arm, the coordination environment around the metal center can feature square planar or octahedral geometries. All four complexes are catalytically active at room temperature in a copper-catalyzed alkyne-azide cycloaddition (CuAAC) reaction using sodium ascorbate as a reducing agent and water-ethanol as a solvent mixture. Complex 8 supported by the NS ligand displayed the best catalytic performance of the series allowing for the easy and high yielding preparation of a variety of mono-, bis- and tris-1,2,3-triazoles under low catalyst loadings.
authors.affiliation: Departamento de Ciencias Básicas, Universidad Autónoma Metropolitana-Azcapotzalco, Avenida San Pablo No. 180, México D.F. 02200, México. gns@correo.azc.uam.mx.
authors.forename: Daniel
authors.initials: D
authors.lastname: Mendoza-Espinosa
authors.forename: Guillermo Enrique
authors.initials: GE
authors.lastname: Negrón-Silva
authors.forename: Deyanira
authors.initials: D
authors.lastname: Ángeles-Beltrán
authors.forename: Alejandro
authors.initials: A
authors.lastname: Álvarez-Hernández
authors.forename: Oscar R
authors.initials: OR
authors.lastname: Suárez-Castillo
authors.forename: Rosa
authors.initials: R
authors.lastname: Santillán