title: FDA's nozzle numerical simulation challenge: non-Newtonian fluid effects and blood damage.
abstract: Data from FDA's nozzle challenge-a study to assess the suitability of simulating fluid flow in an idealized medical device-is used to validate the simulations obtained from a numerical, finite-differences code. Various physiological indicators are computed and compared with experimental data from three different laboratories, getting a very good agreement. Special care is taken with the derivation of blood damage (hemolysis). The paper is focused on the laminar regime, in order to investigate non-Newtonian effects (non-constant fluid viscosity). The code can deal with these effects with just a small extra computational cost, improving Newtonian estimations up to a ten percent. The relevance of non-Newtonian effects for hemolysis parameters is discussed.
authors.affiliation: The Institute of Applied Computing & Community Code (IAC3), University of the Balearic Islands, Palma, Spain.
authors.forename: Miquel
authors.initials: M
authors.lastname: Trias
authors.affiliation: The Institute of Applied Computing & Community Code (IAC3), University of the Balearic Islands, Palma, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Arbona
authors.affiliation: The Institute of Applied Computing & Community Code (IAC3), University of the Balearic Islands, Palma, Spain.
authors.forename: Joan
authors.initials: J
authors.lastname: Massó
authors.affiliation: The Institute of Applied Computing & Community Code (IAC3), University of the Balearic Islands, Palma, Spain.
authors.forename: Borja
authors.initials: B
authors.lastname: Miñano
authors.affiliation: The Institute of Applied Computing & Community Code (IAC3), University of the Balearic Islands, Palma, Spain.
authors.forename: Carles
authors.initials: C
authors.lastname: Bona
mesh_terms: D000818:Animals; D006461:Hemolysis; D006801:Humans; D008955:Models, Cardiovascular