title: Optical tracking of local surface wave for skin viscoelasticity.
abstract: Rapid and effective determination of biomechanical properties is important in examining and diagnosing skin thermal injury. Among the methods used, viscoelasticity quantification is one of the most effective methods in determining such properties. This study aims to rapidly determine skin viscoelasticity by optically tracking the local surface wave. New elastic and viscous coefficients were proposed to indicate skin viscoelasticity based on a single impulse response of the skin. Experiments were performed using fresh porcine skin samples. Surface wave was generated in a single impulse using a vibrator with a ball-tipped device and was detected using a laser Doppler vibrometer. The motions along the depth direction were monitored using an ultrasound system. The ultrasound monitoring results indicated the multi-layered viscoelasticity of the epidermis and dermis. The viscoelastic coefficients from four healthy samples show a potential viscoelasticity variation of porcine skin. In one sample, the two coefficients were evidently higher than those in a healthy area if the skin was slightly burned. These results indicate that the proposed method is sensitive, effective, and quick in determining skin viscoelasticity.
authors.affiliation: The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Department of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 71004, PR China.
authors.forename: Yubo
authors.initials: Y
authors.lastname: Guan
authors.affiliation: The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Department of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 71004, PR China.
authors.forename: Mingzhu
authors.initials: M
authors.lastname: Lu
authors.affiliation: The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Department of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 71004, PR China.
authors.forename: Zhilong
authors.initials: Z
authors.lastname: Shen
authors.affiliation: The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Department of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 71004, PR China. Electronic address: mxwan@mail.xjtu.edu.cn.
authors.forename: Mingxi
authors.initials: M
authors.lastname: Wan
mesh_terms: D000465:Algorithms; D000818:Animals; D001696:Biomechanical Phenomena; D002056:Burns / Q000000981:diagnostic imaging / Q000503:physiopathology; D020405:Dermis / Q000000981:diagnostic imaging / Q000502:physiology / Q000503:physiopathology; D004548:Elasticity; D004817:Epidermis / Q000000981:diagnostic imaging / Q000502:physiology / Q000503:physiopathology; D005240:Feasibility Studies; D061848:Optical Imaging; D010812:Physical Stimulation; D012867:Skin / Q000000981:diagnostic imaging* / Q000503:physiopathology; D012879:Skin Physiological Phenomena; D013552:Swine; D014463:Ultrasonography / Q000379:methods*; D018608:Ultrasonography, Doppler / Q000379:methods; D014732:Vibration; D014783:Viscosity
keywords: Impulse response; Optical tracking; Skin viscoelasticity; Surface wave; Ultrasound monitoring