title: Allocentric spatial neglect with posterior cortical atrophy.
abstract: Patients with posterior cortical atrophy (PCA) have been reported to have neglect in the egocentric/ body-centered reference frame. This report describes a woman with PCA who had a right-sided stimulus-based form of allocentric visual neglect on cancellation, reading, and drawing tests. Her brain imaging revealed left parietal atrophy. The pathophysiology of this disorder may be related to an impairment of the ventral "what" stream's ability to interact with the dorsal "where" stream that mediates the allocation of spatial attention, or a deficit in the systems that allocate contralateral focal attention. Further research is needed to better understand the mechanisms of this disorder and to optimally treat it.
authors.affiliation: a Department of Neurology and Center for Neuropsychological Studies , University of Florida College of Medicine , Gainesville , FL 32610-023 , USA.
authors.forename: Eduardo M
authors.initials: EM
authors.lastname: Zilli
authors.forename: Kenneth M
authors.initials: KM
authors.lastname: Heilman
mesh_terms: D001284:Atrophy; D001288:Attention; D001921:Brain / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009483:Neuropsychological Tests; D010364:Pattern Recognition, Visual; D010468:Perceptual Disorders / Q000209:etiology* / Q000473:pathology*; D013028:Space Perception
keywords: allocentric neglect; egocentric neglect; focal and global attention; posterior cortical atrophy; visual processing systems