title: The benzoyl peroxide promoted dual C-C bond formation via dual C-H bond cleavage: α-phenanthridinylation of ether by isocyanide.
abstract: The benzoyl peroxide-promoted α-phenanthridinylation of ether by isocyanide is developed, proceeding through dual C-H bond cleavage and dual C-C bond formation. The procedure tolerates a series of functional groups, such as methyl, fluoro, chloro, acetyl, methoxy carbonyl, cyano, and trifluoromethyl. Thus, it represents a facile pathway leading to 6-substituted phenanthridine derivatives. The addition of radical to the isonitrile followed by a radical aromatic cyclization is involved in this transformation.
authors.affiliation: School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, Jiangsu Province Key Laboratory of Fine Petrochemical Engineering, Changzhou University , Changzhou 213164, PR China.
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
authors.forename: Wanxing
authors.initials: W
authors.lastname: Sha
authors.forename: Qiang
authors.initials: Q
authors.lastname: Dai
authors.forename: Xiaomei
authors.initials: X
authors.lastname: Feng
authors.forename: Wenting
authors.initials: W
authors.lastname: Wu
authors.forename: Haibo
authors.initials: H
authors.lastname: Peng
authors.forename: Bin
authors.initials: B
authors.lastname: Chen
authors.forename: Jiang
authors.initials: J
authors.lastname: Cheng