title: Prevalence and predictors of poor sleep quality in mild cognitive impairment.
abstract: OBJECTIVE
  To investigate the prevalence of and contributors to poor sleep quality in patients with mild cognitive impairment (MCI).
  
  
  METHODS
  Data were collected for 158 patients meeting the criteria for MCI. Measures included the Pittsburgh Sleep Quality Index, Geriatric Depression Scale, and Mini-Mental State Examination. Demographic, lifestyle, medication, and substance use data were also collected.
  
  
  RESULTS
  A total of 63% of patients with MCI demonstrated sleep disturbance, a significantly higher rate than that of the controls (44%; chi-square = 8.77; P = .003). Depressive symptoms, cognition, antidepressant usage, alcohol consumption, age, and education were identified as significant predictors of self-reported sleep quality in patients with MCI (R(2) = .327, F 6,145 = 11.729, P < .0001).
  
  
  CONCLUSIONS
  Sleep disturbance occurs in around two-thirds of patients with MCI. Interventions addressing depression, cognition, and substance and medication use may improve sleep quality in MCI.
authors.affiliation: Healthy Brain Ageing Clinic, The University of Sydney, Camperdown, NSW, Australia Department of Psychology, Macquarie University, North Ryde, NSW, Australia.
authors.forename: Andrew
authors.initials: A
authors.lastname: McKinnon
authors.affiliation: Healthy Brain Ageing Clinic, The University of Sydney, Camperdown, NSW, Australia.
authors.forename: Zoe
authors.initials: Z
authors.lastname: Terpening
authors.affiliation: Healthy Brain Ageing Clinic, The University of Sydney, Camperdown, NSW, Australia.
authors.forename: Ian B
authors.initials: IB
authors.lastname: Hickie
authors.affiliation: Department of Psychology, Macquarie University, North Ryde, NSW, Australia.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Batchelor
authors.affiliation: Woolcock Institute of Medical Research, NSW, Australia.
authors.forename: Ron
authors.initials: R
authors.lastname: Grunstein
authors.affiliation: Healthy Brain Ageing Clinic, The University of Sydney, Camperdown, NSW, Australia.
authors.forename: Simon J G
authors.initials: SJ
authors.lastname: Lewis
authors.affiliation: Healthy Brain Ageing Clinic, The University of Sydney, Camperdown, NSW, Australia sharon.naismith@sydney.edu.au.
authors.forename: Sharon L
authors.initials: SL
authors.lastname: Naismith
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D060825:Cognitive Dysfunction / Q000453:epidemiology*; D003863:Depression / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D057566:Self Report; D012893:Sleep Wake Disorders / Q000453:epidemiology* / Q000523:psychology
keywords: depression; mild cognitive impairment; sleep disturbance; sleep quality