title: Rapid multi-organ segmentation using context integration and discriminative models.
abstract: We propose a novel framework for rapid and accurate segmentation of a cohort of organs. First, it integrates local and global image context through a product rule to simultaneously detect multiple landmarks on the target organs. The global posterior integrates evidence over all volume patches, while the local image context is modeled with a local discriminative classifier. Through non-parametric modeling of the global posterior, it exploits sparsity in the global context for efficient detection. The complete surface of the target organs is then inferred by robust alignment of a shape model to the resulting landmarks and finally deformed using discriminative boundary detectors. Using our approach, we demonstrate efficient detection and accurate segmentation of liver, kidneys, heart, and lungs in challenging low-resolution MR data in less than one second, and of prostate, bladder, rectum, and femoral heads in CT scans, in roughly one to three seconds and in both cases with accuracy fairly close to inter-user variability.
authors.forename: Nathan
authors.initials: N
authors.lastname: Lay
authors.forename: Neil
authors.initials: N
authors.lastname: Birkbeck
authors.forename: Jingdan
authors.initials: J
authors.lastname: Zhang
authors.forename: S Kevin
authors.initials: SK
authors.lastname: Zhou
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D003198:Computer Simulation; D016002:Discriminant Analysis; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008954:Models, Biological; D015233:Models, Statistical; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018511:Systems Integration; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014781:Viscera / Q000033:anatomy & histology* / Q000000981:diagnostic imaging*