title: Antifungal activity of extracts from Piper aduncum leaves prepared by different solvents and extraction techniques against dermatophytes Trichophyton rubrum and Trichophyton interdigitale.
abstract: The effects of different solvents and extraction techniques upon the phytochemical profile and anti-Trichophyton activity of extracts from Piper aduncum leaves were evaluated. Extract done by maceration method with ethanol has higher content of sesquiterpenes and antifungal activity. This extract may be useful as an alternative treatment for dermatophytosis.
authors.affiliation: Faculdade de Ciências da Saúde, Universidade Vale do Rio Doce, Governador Valadares, MG, Brazil.
authors.forename: Maximillan Leite
authors.initials: ML
authors.lastname: Santos
authors.affiliation: Faculdade de Ciências da Saúde, Universidade Vale do Rio Doce, Governador Valadares, MG, Brazil.
authors.forename: Chaiana Froés
authors.initials: CF
authors.lastname: Magalhães
authors.affiliation: Departamento de Química, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
authors.forename: Marcelo Barcellos
authors.initials: MB
authors.lastname: da Rosa
authors.affiliation: Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
authors.forename: Daniel
authors.initials: D
authors.lastname: de Assis Santos
authors.affiliation: Departamento de Fitotecnia, Universidade Federal de Viçosa, Viçosa, MG, Brazil.
authors.forename: Beatriz Gonçalves
authors.initials: BG
authors.lastname: Brasileiro
authors.affiliation: Departamento de Química, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
authors.forename: Leandro Machado
authors.initials: LM
authors.lastname: de Carvalho
authors.affiliation: Departamento de Ciências Agrárias e Biológicas, Universidade Federal do Espírito Santo, São Mateus, ES, Brazil.
authors.forename: Marcelo Barreto
authors.initials: MB
authors.lastname: da Silva
authors.affiliation: Laboratório de Química de Produtos Naturais, Centro de Pesquisas René Rachou, Fiocruz, Belo Horizonte, MG, Brazil.
authors.forename: Carlos Leomar
authors.initials: CL
authors.lastname: Zani
authors.affiliation: Laboratório de Química de Produtos Naturais, Centro de Pesquisas René Rachou, Fiocruz, Belo Horizonte, MG, Brazil.
authors.forename: Ezequias Pessoa
authors.initials: EP
authors.lastname: de Siqueira
authors.affiliation: Instituto Federal Baiano, Teixeira de Freitas, BA, Brazil.
authors.forename: Rodrigo Loreto
authors.initials: RL
authors.lastname: Peres
authors.affiliation: Faculdade de Ciências da Saúde, Universidade Vale do Rio Doce, Governador Valadares, MG, Brazil. ; Departamento de Microbiologia, Imunologia e Parasitologia, Universidade Federal do Triângulo Mineiro, Uberaba, MG, Brazil.
authors.forename: Anderson Assunção
authors.initials: AA
authors.lastname: Andrade
mesh_terms: D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology*; D003883:Arthrodermataceae / Q000187:drug effects*; D006801:Humans; D031701:Piper / Q000737:chemistry*; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D012717:Sesquiterpenes / Q000302:isolation & purification / Q000494:pharmacology; D014249:Trichophyton / Q000187:drug effects*
chemical_list: D000935:Antifungal Agents; D010936:Plant Extracts; D012717:Sesquiterpenes
keywords: Piper aduncum L.; Trichophyton; antifungal activity; dermatophytes; extraction techniques