title: [The effect of natural whey proteins on mechanisms of blood pressure regulation].
abstract: Whey is a rich natural source of peptides and amino acids. It has been reported in numerous studies that biological active peptides isolated from cow's milk whey may affect blood pressure regulation. Studies on animals and humans have shown that α-lactalbumin and β-lactoglobulin obtained from enzymatically hydrolysed whey inhibit angiotensin converting enzyme (ACE), while lactorphins lower blood pressure by normalizing endothelial function or by opioid receptors dependent mechanism. Whey proteins or their bioactive fragments decrease total cholesterol, LDL fraction and triglycerides, thus reducing the risk factors of cardiovascular diseases. The aim of this review is to discuss the effects of whey proteins on the mechanisms of blood pressure regulation.
authors.affiliation: Zakład Farmakologii Doświadczalnej, Uniwersytet Medyczny w Białymstoku.
authors.forename: Halina
authors.initials: H
authors.lastname: Car
authors.affiliation: Medyczne Laboratorium Diagnostyczne, Niepubliczny Zakład Opieki Zdrowotnej w Białymstoku.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Koprowicz
authors.affiliation: Zakład Farmakologii Doświadczalnej, Uniwersytet Medyczny w Białymstoku.
authors.forename: Anna
authors.initials: A
authors.lastname: Tokajuk
authors.affiliation: Zakład Farmakologii Doświadczalnej, Uniwersytet Medyczny w Białymstoku.
authors.forename: Adrian
authors.initials: A
authors.lastname: Tokajuk
mesh_terms: D000596:Amino Acids / Q000032:analysis / Q000276:immunology / Q000494:pharmacology; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects* / Q000502:physiology*; D006801:Humans; D007768:Lactalbumin / Q000737:chemistry / Q000276:immunology / Q000378:metabolism; D007782:Lactoglobulins / Q000737:chemistry / Q000276:immunology / Q000378:metabolism; D008892:Milk / Q000737:chemistry / Q000276:immunology / Q000378:metabolism; D008894:Milk Proteins / Q000008:administration & dosage* / Q000378:metabolism; D010455:Peptides / Q000032:analysis / Q000276:immunology / Q000494:pharmacology; D007703:Peptidyl-Dipeptidase A / Q000032:analysis / Q000276:immunology / Q000378:metabolism; D000067816:Whey Proteins
chemical_list: D000596:Amino Acids; D007782:Lactoglobulins; D008894:Milk Proteins; D010455:Peptides; D000067816:Whey Proteins; D007768:Lactalbumin; D007703:Peptidyl-Dipeptidase A