title: Dose estimation for internal organs during boron neutron capture therapy for body-trunk tumors.
abstract: Radiation doses during boron neutron capture therapy for body-trunk tumors were estimated for various internal organs, using data from patients treated at Kyoto University Research Reactor Institute. Dose-volume histograms were constructed for tissues of the lung, liver, kidney, pancreas, and bowel. For pleural mesothelioma, the target total dose to the normal lung tissues on the diseased side is 5Gy-Eq in average for the whole lung. It was confirmed that the dose to the liver should be carefully considered in cases of right lung disease.
authors.affiliation: Kyoto University Research Reactor Institute, Asashironishi 2-1010, Kumatori-cho, Sennan-gun, Osaka 590-0494, Japan. Electronic address: yosakura@rri.kyoto-u.ac.jp.
authors.forename: Y
authors.initials: Y
authors.lastname: Sakurai
authors.affiliation: Kyoto University Research Reactor Institute, Asashironishi 2-1010, Kumatori-cho, Sennan-gun, Osaka 590-0494, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Tanaka
authors.affiliation: Kyoto University Research Reactor Institute, Asashironishi 2-1010, Kumatori-cho, Sennan-gun, Osaka 590-0494, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Suzuki
authors.affiliation: Kyoto University Research Reactor Institute, Asashironishi 2-1010, Kumatori-cho, Sennan-gun, Osaka 590-0494, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Masunaga
authors.affiliation: Kyoto University Research Reactor Institute, Asashironishi 2-1010, Kumatori-cho, Sennan-gun, Osaka 590-0494, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Kinashi
authors.affiliation: Kyoto University Research Reactor Institute, Asashironishi 2-1010, Kumatori-cho, Sennan-gun, Osaka 590-0494, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Kondo
authors.affiliation: Kyoto University Research Reactor Institute, Asashironishi 2-1010, Kumatori-cho, Sennan-gun, Osaka 590-0494, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ono
authors.affiliation: Kyoto University Research Reactor Institute, Asashironishi 2-1010, Kumatori-cho, Sennan-gun, Osaka 590-0494, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Maruhashi
mesh_terms: D001895:Boron / Q000493:pharmacokinetics* / Q000627:therapeutic use; D016754:Boron Neutron Capture Therapy / Q000379:methods*; D006801:Humans; D007554:Isotopes / Q000493:pharmacokinetics / Q000627:therapeutic use; D009928:Organ Specificity; D011874:Radiometry / Q000379:methods*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D013899:Thoracic Neoplasms / Q000378:metabolism* / Q000532:radiotherapy*; D014018:Tissue Distribution; D014781:Viscera / Q000378:metabolism*
chemical_list: D007554:Isotopes; D001895:Boron
keywords: Body-trunk tumor; Boron neutron capture therapy; Critical organ; Dose estimation; Dose–volume histogram