title: Good response to chemotherapy spares irradiation for extrarenal rhabdoid tumor conferring better activities of daily living.
abstract: A 7-year-old girl with stage IIA extrarenal rhabdoid tumor near the left cubital fossa received preoperative chemotherapy and surgical resection with median nerve reconstruction followed by postoperative high-dose chemotherapy. As preoperative chemotherapy resulted in decreased tumor size, disappearance of fluorodeoxyglucose-uptake, and pathologic complete response with total tumor resection, irradiation was successfully spared to avoid injury to the reconstructed nerve and inhibition of normal bone development. Two years after diagnosis, recurrence has not been observed and median nerve palsy is improving. This case suggests that radiation therapy could be spared for clinically and pathologically chemotherapy-good-responders in case total surgical resection is achieved.
authors.affiliation: Departments of *Pediatrics †Orthopedic Surgery ‡Plastic and Reconstructive Surgery §Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
authors.forename: Nariaki
authors.initials: N
authors.lastname: Asada
authors.forename: Itaru
authors.initials: I
authors.lastname: Kato
authors.forename: Tomoo
authors.initials: T
authors.lastname: Daifu
authors.forename: Katsutsugu
authors.initials: K
authors.lastname: Umeda
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Hiramatsu
authors.forename: Takeshi
authors.initials: T
authors.lastname: Okamoto
authors.forename: Junya
authors.initials: J
authors.lastname: Toguchida
authors.forename: Satoko
authors.initials: S
authors.lastname: Yamawaki
authors.forename: Katsuhiro
authors.initials: K
authors.lastname: Yoshikawa
authors.forename: Souichi
authors.initials: S
authors.lastname: Adachi
authors.forename: Toshio
authors.initials: T
authors.lastname: Heike
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Watanabe
mesh_terms: D000203:Activities of Daily Living; D002648:Child; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D049268:Positron-Emission Tomography; D018335:Rhabdoid Tumor / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology
chemical_list: D019788:Fluorodeoxyglucose F18