title: Palladium-catalyzed cross-coupling reactions of arylsiloxanes with aryl halides: application to solid-supported organic synthesis.
abstract: The solid-phase version of the Pd-catalyzed Hiyama reaction between a variety of aryltriethoxysilanes and immobilized aryl halides was developed. Smooth cross-coupling was achieved to afford the corresponding biaryl products in moderate to excellent yields. The described protocol would be particularly useful for the construction of 4'-substituted 1,1'-biphenyl derivatives.
authors.affiliation: Instituto de Química Rosario (CONICET-UNR), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario , Suipacha 531, 2000 Rosario, Argentina.
authors.forename: Carla I
authors.initials: CI
authors.lastname: Traficante
authors.forename: Carina M L
authors.initials: CM
authors.lastname: Delpiccolo
authors.forename: Ernesto G
authors.initials: EG
authors.lastname: Mata
mesh_terms: D001713:Biphenyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D010165:Palladium / Q000737:chemistry*; D012821:Silanes / Q000138:chemical synthesis / Q000737:chemistry*; D060327:Solid-Phase Synthesis Techniques / Q000379:methods*
chemical_list: D001713:Biphenyl Compounds; D010165:Palladium; D012821:Silanes; C010574:biphenyl
keywords: Hiyama coupling; cross-coupling reactions; solid-phase organic synthesis