title: Chromones as a privileged scaffold in drug discovery: a review.
abstract: The chromone and its derivatives are the most important heterocyclic compounds, which is a common and integral feature of a variety of natural products and medicinal agents. These heterocycles show a variety of pharmacological properties, and change of their structure offers a high degree of diversity that has proven useful for the search of new therapeutic agents. A large volume of research has been carried out on chromone and their derivatives, which has proved the pharmacological importance of this heterocyclic nucleus. The present review focuses on the pharmacological profile of chromone derivatives in the current literature with an update of recent research findings on this nucleus and the perspectives that they hold for future research.
authors.affiliation: Organic and Medicinal Chemistry Laboratory, Center for Nano and Material Sciences, Jain University, Jain Global Campus, Jakkasandra Post, Kanakapura Road, Ramanagara District, Karnataka 562112, India. Electronic address: keriphd@gmail.com.
authors.forename: Rangappa S
authors.initials: RS
authors.lastname: Keri
authors.affiliation: Organic and Medicinal Chemistry Laboratory, Center for Nano and Material Sciences, Jain University, Jain Global Campus, Jakkasandra Post, Kanakapura Road, Ramanagara District, Karnataka 562112, India.
authors.forename: Srinivasa
authors.initials: S
authors.lastname: Budagumpi
authors.affiliation: Organic and Medicinal Chemistry Laboratory, Center for Nano and Material Sciences, Jain University, Jain Global Campus, Jakkasandra Post, Kanakapura Road, Ramanagara District, Karnataka 562112, India.
authors.forename: Ranjith Krishna
authors.initials: RK
authors.lastname: Pai
authors.affiliation: Organic and Medicinal Chemistry Laboratory, Center for Nano and Material Sciences, Jain University, Jain Global Campus, Jakkasandra Post, Kanakapura Road, Ramanagara District, Karnataka 562112, India.
authors.forename: R Geetha
authors.initials: RG
authors.lastname: Balakrishna
mesh_terms: D000818:Animals; D002867:Chromones / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D055808:Drug Discovery; D006801:Humans; D015394:Molecular Structure
chemical_list: D002867:Chromones
keywords: Chromone; Heterocycles; Pharmacological activities; Synthesis