title: Searching for electrical properties, phenomena and mechanisms in the construction and function of chromosomes.
abstract: OUR STUDIES REVEAL PREVIOUSLY UNIDENTIFIED ELECTRICAL PROPERTIES OF CHROMOSOMES: (1) chromosomes are amazingly similar in construction and function to electrical transformers; (2) chromosomes possess in their construction and function, components similar to those of electric generators, conductors, condensers, switches, and other components of electrical circuits; (3) chromosomes demonstrate in nano-scale level electromagnetic interactions, resonance, fusion and other phenomena similar to those described by equations in classical physics. These electrical properties and phenomena provide a possible explanation for unclear and poorly understood mechanisms in clinical genetics including: (a) electrically based mechanisms responsible for breaks, translocations, fusions, and other chromosomal abnormalities associated with cancer, intellectual disability, infertility, pregnancy loss, Down syndrome, and other genetic disorders; (b) electrically based mechanisms involved in crossing over, non-disjunction and other events during meiosis and mitosis; (c) mechanisms demonstrating heterochromatin to be electrically active and genetically important.
authors.affiliation: Human Genetics Laboratory, Munroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha, Nebraska, 68198-5440, USA.
authors.forename: Ivan
authors.initials: I
authors.lastname: Kanev
authors.affiliation: Department of physics, University of Nebraska at Omaha, Nebraska, 68182, USA.
authors.forename: Wai-Ning
authors.initials: WN
authors.lastname: Mei
authors.affiliation: Applied Electrostatics Laboratory, Department of Environmental and Life Sciences, Toyohashi University of Technology, Tempaku-cyo, Toyohashi, Aichi, 441-8580, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Mizuno
authors.affiliation: Human Genetics Laboratory, Munroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha, Nebraska, 68198-5440, USA.
authors.forename: Kristi
authors.initials: K
authors.lastname: Dehaai
authors.affiliation: Human Genetics Laboratory, Munroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha, Nebraska, 68198-5440, USA.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Sanmann
authors.affiliation: Human Genetics Laboratory, Munroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha, Nebraska, 68198-5440, USA.
authors.forename: Michelle
authors.initials: M
authors.lastname: Hess
authors.affiliation: Human Genetics Laboratory, Munroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha, Nebraska, 68198-5440, USA.
authors.forename: Lois
authors.initials: L
authors.lastname: Starr
authors.affiliation: Human Genetics Laboratory, Munroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha, Nebraska, 68198-5440, USA.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Grove
authors.affiliation: Human Genetics Laboratory, Munroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha, Nebraska, 68198-5440, USA.
authors.forename: Bhavana
authors.initials: B
authors.lastname: Dave
authors.affiliation: Human Genetics Laboratory, Munroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha, Nebraska, 68198-5440, USA.
authors.forename: Warren
authors.initials: W
authors.lastname: Sanger