title: Hypoxia among patients on the liver-transplant waiting list.
abstract: BACKGROUND
  Hepatopulmonary syndrome is formed by a triad of liver disease, intrapulmonary vascular dilatation and changes in blood gases. This condition is present in 4-32% of patients with cirrhosis.
  
  
  OBJECTIVE
  To analyze the blood gas changes data of patients in liver-transplant waiting list.
  
  
  METHODS
  Clinical data of 279 patients in liver transplantation waiting list in May 2013 were studied. Overall patient was analyzed by the demographic aspects, laboratorial and image findings on exams that determine lung disease (hypoxemia) in these cirrhotic patients. The mean values and standard deviations were used to examine normally distributed variables.
  
  
  RESULTS
  There was a high prevalence of male patients (68%); the mean age was 51(± 5,89) years, and the predominant reason for listing was hepatitis C cirrhosis. The MELD score mean was 16 ± 5,89, without prioritization or special situation. The most common blood type was O in 129 cases (46%) and the mean of body max index was 25,94 ± 4,58. Regarding arterial blood gas tests was observed 214 patients with PaO2 <90 mmHg, 80 with PaO2 <80 mmHg and 39 with PaO2 <50 mmHg. In relation to O2 saturation, 50 patients had <90%, 33 <80% and 10 <50%.
  
  
  CONCLUSIONS
  Was observed a high rate of hypoxemia in patients on waiting list liver transplant. Due to the high severity and morbidity, is suggested better monitoring and therapeutic support to hypoxemic patients on liver transplant waiting list.
authors.affiliation: Department of Gastroenterology, School of Medicine, University of Sao Paulo, Sao Paulo, SP, Brazil.
authors.forename: Lucas Souto
authors.initials: LS
authors.lastname: Nacif
authors.affiliation: Department of Gastroenterology, School of Medicine, University of Sao Paulo, Sao Paulo, SP, Brazil.
authors.forename: Wellington
authors.initials: W
authors.lastname: Andraus
authors.affiliation: Department of Gastroenterology, School of Medicine, University of Sao Paulo, Sao Paulo, SP, Brazil.
authors.forename: Kathryn
authors.initials: K
authors.lastname: Sartori
authors.affiliation: Department of Gastroenterology, School of Medicine, University of Sao Paulo, Sao Paulo, SP, Brazil.
authors.forename: Carlos Marlon
authors.initials: CM
authors.lastname: Benites
authors.affiliation: Department of Gastroenterology, School of Medicine, University of Sao Paulo, Sao Paulo, SP, Brazil.
authors.forename: Vinicius Rocha
authors.initials: VR
authors.lastname: Santos
authors.affiliation: Department of Gastroenterology, School of Medicine, University of Sao Paulo, Sao Paulo, SP, Brazil.
authors.forename: Joel Avancini
authors.initials: JA
authors.lastname: Rocha-Filho
authors.affiliation: Department of Gastroenterology, School of Medicine, University of Sao Paulo, Sao Paulo, SP, Brazil.
authors.forename: Luiz Carneiro
authors.initials: LC
authors.lastname: D'Albuquerque
mesh_terms: D001784:Blood Gas Analysis; D005260:Female; D020065:Hepatopulmonary Syndrome / Q000097:blood / Q000150:complications* / Q000601:surgery; D006801:Humans; D000860:Hypoxia / Q000097:blood / Q000453:epidemiology* / Q000209:etiology*; D008103:Liver Cirrhosis; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D014850:Waiting Lists