title: Periodontal infection and cardiorespiratory fitness in younger adults: results from continuous national health and nutrition examination survey 1999-2004.
abstract: OBJECTIVE
  Previous studies report associations between periodontal infection and cardiorespiratory fitness but no study has examined the association among younger adults. Our objective was to study the association between clinical measures of periodontal infection and cardiorespiratory fitness levels among a population-based sample of younger adults.
  
  
  METHODS
  The Continuous National Health and Nutrition Examination Survey 1999-2004 enrolled 2,863 participants (46% women) who received a partial-mouth periodontal examination and completed a submaximal treadmill test for the assessment of estimated VO2 max(eVO2 max ). Participants were mean±SD age 33±9 years (range = 20-49 years), 30% Hispanic, 48% White, 19% Black, and 3% other. Mean eVO2 max (mL/kg/minute) as well as eVO2 max≤32 mL/kg/minute (20th percentile) were regressed across quartiles of mean probing depth and mean attachment loss in multivariable linear and logistic regression models.
  
  
  RESULTS
  After multivariable adjustment, mean eVO2 max levels±SE across quartiles of attachment loss were 39.72±0.37, 39.64±0.34, 39.59±0.36, and 39.85±0.39 (P = 0.99). Mean eVO2 max±SE across quartiles of probing depth were 39.57±0.32, 39.78±0.38, 39.19±0.25, and 40.37±0.53 (P = 0.28). Similarly, multivariable adjusted mean eVO2 max values were similar between healthy participants vs. those with moderate/severe periodontitis: 39.70±0.21 vs. 39.70±0.90 (P = 1.00). The odds ratio (OR) for low eVO2 max comparing highest vs. lowest quartile of attachment loss = 0.89[95% CI 0.64-1.24]. The OR for comparing highest vs. lowest probing depth quartile = 0.77[95% CI 0.51-1.15].
  
  
  CONCLUSIONS
  Clinical measures of periodontal infection were not related to cardiorespiratory fitness in a sample of generally healthy younger adults.
authors.affiliation: Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, United States of America.
authors.forename: Ashley
authors.initials: A
authors.lastname: Thai
authors.affiliation: Division of Periodontics, Section of Oral and Diagnostic Sciences, College of Dental Medicine, Columbia University, New York, New York, United States of America.
authors.forename: Panos N
authors.initials: PN
authors.lastname: Papapanou
authors.affiliation: Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, United States of America; Department of Nutrition, University of Oslo, Oslo, Norway.
authors.forename: David R
authors.initials: DR
authors.lastname: Jacobs
authors.affiliation: Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, United States of America; Centre de recherche Epidémiologies et Biostatistique, INSERM U1153, Equipe: Méthodes en évaluation thérapeutique des maladies chroniques, Paris, France.
authors.forename: Moïse
authors.initials: M
authors.lastname: Desvarieux
authors.affiliation: Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, United States of America.
authors.forename: Ryan T
authors.initials: RT
authors.lastname: Demmer
mesh_terms: D000328:Adult; D002320:Cardiovascular Physiological Phenomena; D005260:Female; D006262:Health; D006801:Humans; D007239:Infections / Q000453:epidemiology / Q000503:physiopathology*; D008297:Male; D009749:Nutrition Surveys; D010510:Periodontal Diseases / Q000453:epidemiology / Q000503:physiopathology*; D012143:Respiratory Physiological Phenomena