title: From acetone metalation to the catalytic α-arylation of acyclic ketones with NHC-nickel(II) complexes.
abstract: Air-stable N-heterocyclic carbene-nickel(ii) complexes at concentrations as low as 1 mol% exhibit high catalytic activity for the α-arylation of acyclic ketones and join a highly restricted list of nickel catalysts for this key reaction. Mechanistic investigations suggest a radical pathway.
authors.affiliation: Laboratoire de Chimie Organométallique Appliquée, UMR CNRS 7509, Ecole européenne de Chimie, Polymères et Matériaux, Université de Strasbourg, 25 rue Becquerel, 67087 Strasbourg, France. vritleng@unistra.fr michael.chetcuti@unistra.fr.
authors.forename: Mickaël
authors.initials: M
authors.lastname: Henrion
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Chetcuti
authors.forename: Vincent
authors.initials: V
authors.lastname: Ritleng
mesh_terms: D000096:Acetone / Q000737:chemistry*; D002384:Catalysis; D056831:Coordination Complexes / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry; D006841:Hydrocarbons, Aromatic / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D008958:Models, Molecular; D009532:Nickel / Q000737:chemistry*
chemical_list: D056831:Coordination Complexes; D006571:Heterocyclic Compounds; D006841:Hydrocarbons, Aromatic; D007659:Ketones; D000096:Acetone; C030011:carbene; D009532:Nickel; D008697:Methane