title: Advantages of the net benefit regression framework for economic evaluations of interventions in the workplace: a case study of the cost-effectiveness of a collaborative mental health care program for people receiving short-term disability benefits for psychiatric disorders.
abstract: OBJECTIVE
  Economic evaluations commonly accompany trials of new treatments or interventions; however, regression methods and their corresponding advantages for the analysis of cost-effectiveness data are not well known.
  
  
  METHODS
  To illustrate regression-based economic evaluation, we present a case study investigating the cost-effectiveness of a collaborative mental health care program for people receiving short-term disability benefits for psychiatric disorders. We implement net benefit regression to illustrate its strengths and limitations.
  
  
  RESULTS
  Net benefit regression offers a simple option for cost-effectiveness analyses of person-level data. By placing economic evaluation in a regression framework, regression-based techniques can facilitate the analysis and provide simple solutions to commonly encountered challenges.
  
  
  CONCLUSIONS
  Economic evaluations of person-level data (eg, from a clinical trial) should use net benefit regression to facilitate analysis and enhance results.
authors.affiliation: From the Institute of Health Policy, Management and Evaluation (Drs Hoch and Dewa), University of Toronto; Centre for Excellence in Economic Analysis and Research (Dr Hoch), Li Ka Shing Knowledge Institute, St Michael's Hospital; Department of Psychiatry (Dr Dewa), University of Toronto, and Centre for Research on Employment and Workplace Health, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Hoch
authors.forename: Carolyn S
authors.initials: CS
authors.lastname: Dewa
mesh_terms: D019090:Case Management / Q000191:economics*; D003362:Cost-Benefit Analysis; D006233:Persons with Disabilities / Q000534:rehabilitation*; D006801:Humans; D018868:Insurance, Disability / Q000191:economics*; D001523:Mental Disorders / Q000534:rehabilitation*; D012044:Regression Analysis; D017132:Workplace / Q000191:economics*