title: Use of fibrin glue for fixation of mesh and approximation of Peritoneum in Transabdominal Preperitoneal (TAPP) inguinal hernia repair: technical feasibility and early surgical outcomes.
abstract: BACKGROUND
  It is a common practice to secure both mesh and peritoneum using tacks when performing a transabdominal preperitoneal (TAPP) inguinal hernia repair. The use of tacks to secure the mesh is well documented and has been associated with postoperative chronic pain. Recently, fibrin glue has been used to secure the mesh in these repairs but not used to reapproximate the incised peritoneum. This study assessed the technical feasibility of using fibrin glue for fixation of both mesh and peritoneum.
  
  
  METHODS
  A total of 33 TAPP hernia repairs were carried out in 27 consecutive patients. In all the patients, both mesh and peritoneum were secured with fibrin glue (20 primary inguinal hernia repairs, 5 bilateral hernia repairs, 1 recurrent inguinal hernia, and 1 recurrent bilateral hernia repair).
  
  
  RESULTS
  Patients were followed up at an outpatient clinic between the second and third week after surgery. Six patients were followed up through telephone. Patients were questioned on the following factors: residual postoperative pain (groin and port sites), unplanned GP or hospital visits, employment status and number of days between their surgery and return to both work and normal activities, and recurrence. No patients had residual groin or port site pain at a median of 21 days after surgery. No patient required an unplanned follow-up appointment with their GP. One patient (recurrent repair) developed a seroma postoperatively. Median time to normal activities was 10 days (range, 3 to 21 d).
  
  
  CONCLUSIONS
  Total glue fixation of mesh and peritoneum is technically feasible and early results show low rates of postoperative complications and pain. Randomized studies are needed to confirm this.
authors.affiliation: *Department of General Surgery, Freeman Hospital, Newcastle-upon-Tyne †Department of General Surgery, James Cook University Hospital, Middlesbrough, UK.
authors.forename: Alexander W
authors.initials: AW
authors.lastname: Phillips
authors.forename: Yirupaiahgari K S
authors.initials: YK
authors.lastname: Viswanath
authors.forename: Jessica K
authors.initials: JK
authors.lastname: Burns
authors.forename: Catriona E J
authors.initials: CE
authors.lastname: Hall
authors.forename: Alan F
authors.initials: AF
authors.lastname: Horgan
mesh_terms: D000005:Abdomen; D005240:Feasibility Studies; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006552:Hernia, Inguinal / Q000534:rehabilitation / Q000601:surgery*; D006801:Humans; D010149:Postoperative Pain; D010537:Peritoneum; D011183:Postoperative Complications; D012008:Recurrence; D049291:Seroma / Q000209:etiology; D013526:Surgical Mesh; D016896:Treatment Outcome
chemical_list: D015718:Fibrin Tissue Adhesive