title: Regenerative medicine. Knocking on the door to successful hepatocyte transplantation.
abstract: With the ongoing shortage of livers available for transplantation, attention has turned to cell-based approaches to support liver function and enable liver regeneration. However, hepatocyte transplantation is beset with problems and a clinically adoptable strategy is lacking. How can a plentiful supply of hepatocyte-like cells with long-term proliferation be generated?
authors.affiliation: MRC Centre for Regenerative Medicine, Scottish Centre for Regenerative Medicine, 5 Little France Drive, Edinburgh EH16 4UU, UK.
authors.forename: Stuart J
authors.initials: SJ
authors.lastname: Forbes
authors.affiliation: Centre for Tumour Biology, Barts and The London School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK.
authors.forename: Malcolm R
authors.initials: MR
authors.lastname: Alison
mesh_terms: D000818:Animals; D005260:Female; D005347:Fibroblasts / Q000166:cytology*; D022781:Hepatocytes / Q000166:cytology* / Q000637:transplantation*; D006801:Humans; D008099:Liver / Q000166:cytology*; D008297:Male