title: Genome-wide transcriptome modulation in rice transgenic lines expressing engineered mitogen activated protein kinase kinase 6.
abstract: Mitogen activated protein kinase kinase (MAPKK) is the central module of MAPK cascade and also point of signal integration and divergence. To investigate the regulatory role of OsMKK6, the regulon of genes controlled by OsMKK6 was constructed by microarray analysis between constitutively activated overexpressing transgenic lines and the wild type rice. Regulated genes were identified in overexpressed constitutively activated OsMKK6 and they were further subdivided on the basis of functional categories, viz. transcription, metabolism, signaling, defense and unknown function. These findings suggest the possible physiological role of OsMKK6 in modulating gene expression and signaling pathways during different stresses.
authors.affiliation: National Institute of Plant Genome Research; Aruna Asaf Ali Road; New Delhi, India.
authors.forename: Kundan
authors.initials: K
authors.lastname: Kumar
authors.affiliation: National Institute of Plant Genome Research; Aruna Asaf Ali Road; New Delhi, India.
authors.forename: Alok Krishna
authors.initials: AK
authors.lastname: Sinha
mesh_terms: D029681:Arabidopsis Proteins / Q000378:metabolism; D020869:Gene Expression Profiling; D018506:Gene Expression Regulation, Plant; D048669:MAP Kinase Kinase 6 / Q000378:metabolism*; D020411:Oligonucleotide Array Sequence Analysis; D012275:Oryza / Q000201:enzymology* / Q000235:genetics; D059467:Transcriptome
chemical_list: D029681:Arabidopsis Proteins; D048669:MAP Kinase Kinase 6
keywords: MAPKK; MAPKK6; Microarray; Mitogen activated protein kinase kinase; Oryza sativa; Rice