title: Retrospective observations on the ability to diagnose and manage patients with asthma through the use of impulse oscillometry: comparison with spirometry and overview of the literature.
abstract: OBJECTIVE
  Impulse oscillometry (IOS) is an evolving technology for the diagnosis and followup of patients with asthma. Our objective is to review the findings on patients who underwent both spirometry and IOS during clinical evaluations of their asthma. The goal was to retrospectively evaluate IOS during the initial diagnosis and followup of patients with asthma in comparison with spirometry.
  
  
  METHODS
  We routinely perform IOS and spirometry evaluation in patients with suspected asthma during baseline visits and at followup. We reviewed the data on 39 patients over the age of 13 with asthma at baseline and following treatment with inhaled corticosteroids. IOS and spirometry were both done at baseline, following short acting bronchodilator administration, and at followup after at least three months of inhaled corticosteroid treatment.
  
  
  RESULTS
  IOS showed improvement in airway function both initially, following short acting bronchodilator introduction, and later after initiation of long term inhaled corticosteroid treatment, even when the spirometry did not reveal improvement. We noted the IOS improvement in the reactance or AX as well as the resistance in smaller airways or R5.
  
  
  CONCLUSIONS
  IOS may provide a useful measure towards identifying an asthma diagnosis and followup without inducing the extra respiratory effort spirometry requires.
authors.affiliation: Amarillo Center for Clinical Research (ACCR), TX, USA ; Allergy, Asthma, Rheumatology Treatment Specialist (Allergy ARTS), 6842 Plum Creek Dr, Amarillo, TX 79124, USA ; Texas Tech University Health Sciences Center, USA.
authors.forename: Constantine
authors.identifier: 0000-0002-4417-5289
authors.initials: C
authors.lastname: Saadeh
authors.affiliation: Amarillo Center for Clinical Research (ACCR), TX, USA ; Allergy, Asthma, Rheumatology Treatment Specialist (Allergy ARTS), 6842 Plum Creek Dr, Amarillo, TX 79124, USA.
authors.forename: Blake
authors.identifier: 0000-0002-3084-9502
authors.initials: B
authors.lastname: Cross
authors.affiliation: Amarillo Center for Clinical Research (ACCR), TX, USA ; Allergy, Asthma, Rheumatology Treatment Specialist (Allergy ARTS), 6842 Plum Creek Dr, Amarillo, TX 79124, USA ; Texas Tech University Health Sciences Center, USA.
authors.forename: Charles
authors.initials: C
authors.lastname: Saadeh
authors.affiliation: Amarillo Center for Clinical Research (ACCR), TX, USA ; Allergy, Asthma, Rheumatology Treatment Specialist (Allergy ARTS), 6842 Plum Creek Dr, Amarillo, TX 79124, USA ; University of North Texas School for Osteopathic Medicine, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Gaylor
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001249:Asthma / Q000175:diagnosis* / Q000188:drug therapy; D001993:Bronchodilator Agents / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D009991:Oscillometry / Q000379:methods; D012189:Retrospective Studies; D013147:Spirometry; D055815:Young Adult
chemical_list: D000305:Adrenal Cortex Hormones; D001993:Bronchodilator Agents