title: [Influence of medical and neuropsychiatric comorbidities on the course of childhood epilepsy].
abstract: BACKGROUND
  Comorbidity has a significant influence in the management of patients with epilepsy.
  
  
  METHODS
  A descriptive study of all patients with epilepsy, from a suburban area in the Community of Madrid followed up for at least 1 year. Children under 2 years, those with symptomatic acute febrile seizures were excluded.
  
  
  RESULTS
  Out of a total of 46 patients (54% male, age median 9.1 years), more than half (52.5%) were on monotherapy, 45.7% were "free of seizures", 23.9% had "drug resistant epilepsy", and 30.4% were "undetermined". As regards comorbidities, 28.3% had chronic medical conditions, and 41.3% associated neuropsychiatric disorders. In32.6%, the seizures were of sudden onset, and those with chronic medical and neuropsychiatric comorbidities had a risk of 15 and 8.3 times, respectively, than those patients without comorbidities.
  
  
  CONCLUSIONS
  Comorbidities may have an important role in the course of epilepsy.
authors.affiliation: Unidad de Neuropediatría, Hospital Universitario Infanta Cristina, Madrid, España. Electronic address: adrian.garciar@salud.madrid.org.
authors.forename: A
authors.initials: A
authors.lastname: García Ron
authors.affiliation: Unidad de Neuropediatría, Hospital Universitario Infanta Cristina, Madrid, España.
authors.forename: R
authors.initials: R
authors.lastname: Blanco Lago
authors.affiliation: Servicio de Neurología, Hospital Universitario Infanta Cristina, Madrid, España.
authors.forename: L
authors.initials: L
authors.lastname: Ballesteros Plaza
authors.affiliation: Servicio de Neurología, Hospital Universitario Infanta Cristina, Madrid, España.
authors.forename: J
authors.initials: J
authors.lastname: Herreros Rodríguez
authors.affiliation: Servicio de Neurología, Hospital Universitario Infanta Cristina, Madrid, España.
authors.forename: A
authors.initials: A
authors.lastname: de la Morena
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000209:etiology*; D009422:Nervous System Diseases / Q000209:etiology; D012189:Retrospective Studies
keywords: Calidad de vida; Comorbilidad médica; Comorbilidad psiquiátrica; Drug-resistant epilepsy; Epilepsia; Epilepsia refractaria; Medical comorbidity; Neurodevelopmental disorders; Psychiatric comorbidity; Quality of life: Epilepsy; Trastornos del neurodesarrollo