title: Prognostic factors for gastrectomy in elderly patients.
abstract: The decision to undergo surgery for gastric cancer patients aged ≥85 years should be made carefully. We retrospectively reviewed the prognostic factors of gastrectomy for 64 patients aged ≥85 years who had undergone curative gastrectomy for gastric cancer. The effects of various clinical characteristics and surgical interventions on survival were retrospectively analyzed. Univariate analysis revealed that sex (male/female; P = 0.001), the extent of gastric resection (total/distal; P = 0.028), the extent of lymph node dissection (D2/<D2; P = 0.019), and blood loss (P = 0.005) were significant prognostic factors for overall survival. Multivariate analysis demonstrated that sex was the only independent prognostic factor. For pneumonia-specific survival, sex was also the only prognostic factor by multivariate analysis.Prognoses of males aged ≥85 years after gastrectomy were significantly worse than those of females, as they were more likely to die of pneumonia.
authors.affiliation: 1 Department of Surgery, National Hospital Organization Kure Medical Center/Chugoku Cancer Center, Hiroshima, Japan.
authors.forename: Shunji
authors.initials: S
authors.lastname: Endo
authors.forename: Yukinobu
authors.initials: Y
authors.lastname: Yoshikawa
authors.forename: Nobutaka
authors.initials: N
authors.lastname: Hatanaka
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Dousei
authors.forename: Terumasa
authors.initials: T
authors.lastname: Yamada
authors.forename: Junichi
authors.initials: J
authors.lastname: Nishijima
authors.forename: Wataru
authors.initials: W
authors.lastname: Kamiike
mesh_terms: D000369:Aged, 80 and over; D005260:Female; D005743:Gastrectomy / Q000401:mortality*; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D015999:Multivariate Analysis; D011183:Postoperative Complications / Q000401:mortality; D011379:Prognosis; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000401:mortality / Q000601:surgery*; D015996:Survival Rate