title: An unusually large spindle cell sarcoma of the tongue in a male child.
abstract: Reports of spindle cell sarcoma in the tongue are very rare, and seldom in the child. We report a five-year-old male patient who presented with a massive lesion on the right side of the tongue. This was surgically excised and histologically diagnosed as a Spindle cell Sarcoma. Results of bone marrow aspiration further revealed that about 16% of his bone marrow was infiltrated with abnormal pleomorphic vacuolated cells with bluish cytoplasm, consistent with rhabdomyosarcoma (RMS) cells. The child was treated with surgery and chemotherapy with good initial response, but then died after one year following a relapse.
authors.affiliation: Department of Oral and Maxillofacial Surgery, University of Ghana Dental School, Korle-Bu Teaching Hospital, Accra, Ghana.
authors.forename: A E
authors.initials: AE
authors.lastname: Abdulai
authors.affiliation: Department of Oral and Maxillofacial Surgery, University of Ghana Dental School, Korle-Bu Teaching Hospital, Accra, Ghana.
authors.forename: I K
authors.initials: IK
authors.lastname: Nuamah
authors.affiliation: Department of Oral and Maxillofacial Surgery, University of Ghana Dental School, Korle-Bu Teaching Hospital, Accra, Ghana.
authors.forename: D
authors.initials: D
authors.lastname: Avogo
authors.affiliation: Department of Pathology, University of Ghana Medical School, Korle-Bu Teaching Hospital, Accra, Ghana.
authors.forename: R K
authors.initials: RK
authors.lastname: Gyasi
authors.affiliation: Department of Child Health, University of Ghana Medical School, Korle-Bu Teaching Hospital, Accra, Ghana.
authors.forename: L A
authors.initials: LA
authors.lastname: Renner
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002675:Child, Preschool; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery / Q000628:therapy*; D012208:Rhabdomyosarcoma / Q000473:pathology / Q000628:therapy; D012509:Sarcoma / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery / Q000628:therapy*; D013997:Time Factors; D014062:Tongue Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery / Q000628:therapy*; D017211:Treatment Failure; D016896:Treatment Outcome
keywords: Child; Male; Sarcoma; Spindle Cell; Tongue