title: Effects of endurance exercise training on risk components for metabolic syndrome, interleukin-6, and the exercise capacity of postmenopausal women.
abstract: We conducted this study to investigate how an exercise program affects the risk components of metabolic syndrome (MS), serum interleukin (IL)-6 levels, and exercise capacity in postmenopausal women. A randomized clinical trial design was used. Women in an exercise group participated in a treadmill-exercise program for 12 weeks, whereas women in a control group maintained their customary lifestyle. Data on variables were collected at baseline and after 12 weeks of the study, which was completed by 46 women (mean age, 56.0 ± 7.0 y). Our results indicate endurance exercise exerted significant beneficial effects on waist circumference, serum high-density lipoprotein cholesterol (HDL-C) and IL-6 levels, and exercise capacity (all P < 0.05). The beneficial effects on IL-6 and exercise capacity were correlated with improvements in HDL-C levels (r = -0.33, P = 0.03 and r = 0.31, P = 0.04, respectively). Our results suggest that health-care providers can incorporate an exercise program in treatments to improve the health of postmenopausal women.
authors.affiliation: Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan, R.O.C; Department of Nursing, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan, R.O.C.
authors.forename: Chia-Hui
authors.initials: CH
authors.lastname: Wang
authors.affiliation: Graduate Institute of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan, R.O.C.
authors.forename: Min-Huey
authors.initials: MH
authors.lastname: Chung
authors.affiliation: College of Nursing, Taipei Medical University, Taipei, Taiwan, R.O.C; Division of Cardiovascular Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan, R.O.C.
authors.forename: Paul
authors.initials: P
authors.lastname: Chan
authors.affiliation: School of Nursing, National Yang-Ming University, No.155, Sec. 2, Linong Street, Taipei 112, Taiwan, R.O.C. Electronic address: jenchent@ym.edu.tw.
authors.forename: Jen-Chen
authors.initials: JC
authors.lastname: Tsai
authors.affiliation: Department of Laboratory Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan, R.O.C.
authors.forename: Feng-Chia
authors.initials: FC
authors.lastname: Chen
mesh_terms: D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000502:physiology*; D024821:Metabolic Syndrome / Q000503:physiopathology*; D008875:Middle Aged; D010807:Physical Endurance; D017698:Postmenopause; D012307:Risk Factors
chemical_list: D015850:Interleukin-6
keywords: Exercise capacity; Exercise training; Interleukin-6; Metabolic syndrome; Postmenopausal women