title: Enantiodifferentiation through frequency-selective pure-shift (1)H nuclear magnetic resonance spectroscopy.
abstract: A frequency-selective 1D (1) H nuclear magnetic resonance (NMR) experiment for the fast and sensitive determination of chemical-shift differences between overlapped resonances is proposed. The resulting fully homodecoupled (1) H NMR resonances appear as resolved 1D singlets without their typical J(HH) coupling constant multiplet structures. The high signal dispersion that is achieved is then exploited in enantiodiscrimination studies by using chiral solvating agents.
authors.affiliation: Servei de Ressonància Magnètica Nuclear and Departament de Química, Universitat Autònoma de Barcelona, 08193 Bellaterra (Spain), Tel: (+34) 935812291.
authors.forename: Laura
authors.initials: L
authors.lastname: Castañar
authors.forename: Míriam
authors.initials: M
authors.lastname: Pérez-Trujillo
authors.forename: Pau
authors.initials: P
authors.lastname: Nolis
authors.forename: Eva
authors.initials: E
authors.lastname: Monteagudo
authors.forename: Albert
authors.initials: A
authors.lastname: Virgili
authors.forename: Teodor
authors.initials: T
authors.lastname: Parella
keywords: chemical shift; enantioselectivity; homodecoupling; nmr spectroscopy; single pulsed-field-gradient echo