title: Clinical evaluation of desensitizing treatment for incisor teeth affected by molar-incisor hypomineralization.
abstract: BACKGROUND
  Sensitivity complaints are commonly observed in teeth affected by MIH (molar incisor hypomineralization).
  
  
  OBJECTIVE
  This study aimed to evaluate the hypersensitivity observed in MIH-affected teeth and the effect of desensitizing agents applied with and without ozone to incisors affected by MIH.
  
  
  METHODS
  The first part of the study included 120 teeth from 42 patients with MIH. These 42 patients included 33 children with 92 incisor teeth with a Vas score of > or = 30, and these 92 incisors were included in the second part of the study. The patients included in the second part were divided into three main groups and six subgroups. The main groups included the following: fluoride, CPP-ACP and CPP-ACP with fluoride. Each main group was divided into two subgroups: one with ozone use and one without ozone use.
  
  
  RESULTS
  Girls exhibited significantly more sensitivity compared with boys (p < 0.05). There were significant decreases in hypersensitivity compared to baseline in all of the groups (p < 0.05). There were no differences among the groups at the end of the study (p > 0.05).
  
  
  CONCLUSIONS
  The results of this study revealed that gender is an important factor in the sensitivity of teeth with MLH. Desensitizing agents effectively reduced the hypersensitivity of teeth with MIH. CPP-ACP paste was found to be more effective, and ozone therapy prolonged the effect of CPP-ACP paste.
authors.forename: Betül Memiş
authors.initials: BM
authors.lastname: Ozgül
authors.forename: Sinem
authors.initials: S
authors.lastname: Saat
authors.forename: Hayriye
authors.initials: H
authors.lastname: Sönmez
authors.forename: Firdevs Tulga
authors.initials: FT
authors.lastname: Oz
mesh_terms: D002327:Cariostatic Agents / Q000627:therapeutic use; D002364:Caseins / Q000627:therapeutic use; D002648:Child; D003744:Dental Enamel Hypoplasia / Q000150:complications*; D057133:Dentin Desensitizing Agents / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005460:Fluorides, Topical / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007180:Incisor / Q000187:drug effects*; D008297:Male; D010083:Oxidants, Photochemical / Q000627:therapeutic use; D010126:Ozone / Q000627:therapeutic use; D010147:Pain Measurement; D012737:Sex Factors; D016896:Treatment Outcome
chemical_list: D002327:Cariostatic Agents; D002364:Caseins; D057133:Dentin Desensitizing Agents; D005460:Fluorides, Topical; D010083:Oxidants, Photochemical; C447032:casein phosphopeptide-amorphous calcium phosphate nanocomplex; D010126:Ozone