title: Effect of antioxidant potential of tropical fruit juices on antioxidant enzyme profiles and lipid peroxidation in rats.
abstract: Fruits are a rich source of a variety of biologically active compounds that can have complementary and overlapping mechanisms of action, including detoxification, enzyme modulation and antioxidant effects. Although the effects of tropical fruits have been examined individually, the interactive antioxidant capacity of the bioactive compounds in these formulations has not been sufficiently explored. For this reason, this study investigated the effect of two tropical fruit juices (FA and FB) on lipid peroxidation and antioxidant enzymes in rats. Seven groups, with eight rats each, were fed a normal diet for 4 weeks, and were force-fed daily either water (control), 100, 200, or 400 mg of FA or FB per kg. The results showed that the liver superoxide dismutase and catalase activities (FA200), erythrocytes glutathione peroxidase (FB400) and thiobarbituric acid-reactive substances (FB100, FA400, FB200, FB400) were efficiently reduced by fruit juices when compared with control; whereas HDL-c increased (FB400).
authors.affiliation: Universidade Federal do Ceará, Departamento de Tecnologia de Alimentos, Av. Mister Hull 2977, Bloco 858, CEP 60356-000, Fortaleza, CE, Brazil.
authors.forename: Ana Carolina da Silva
authors.initials: AC
authors.lastname: Pereira
authors.affiliation: Embrapa Agroindustria Tropical, Rua Dra. Sara Mesquita, 2270, Bairro Planalto Pici - C.P. 3761, CEP 60511-110, Fortaleza, CE, Brazil. Electronic address: ana.dionisio@embrapa.br.
authors.forename: Ana Paula
authors.initials: AP
authors.lastname: Dionísio
authors.affiliation: Embrapa Agroindustria Tropical, Rua Dra. Sara Mesquita, 2270, Bairro Planalto Pici - C.P. 3761, CEP 60511-110, Fortaleza, CE, Brazil.
authors.forename: Nedio Jair
authors.initials: NJ
authors.lastname: Wurlitzer
authors.affiliation: Embrapa Agroindustria Tropical, Rua Dra. Sara Mesquita, 2270, Bairro Planalto Pici - C.P. 3761, CEP 60511-110, Fortaleza, CE, Brazil.
authors.forename: Ricardo Elesbão
authors.initials: RE
authors.lastname: Alves
authors.affiliation: Embrapa Agroindustria Tropical, Rua Dra. Sara Mesquita, 2270, Bairro Planalto Pici - C.P. 3761, CEP 60511-110, Fortaleza, CE, Brazil.
authors.forename: Edy Souza
authors.initials: ES
authors.lastname: de Brito
authors.affiliation: Universidade de São Paulo (USP), Faculdade de Ciências Farmacêuticas, Departamento de Alimentos e Nutrição Experimental, CEP 05508-000, São Paulo, SP, Brazil.
authors.forename: Ana Mara de Oliveira
authors.initials: AM
authors.lastname: e Silva
authors.affiliation: Universidade Federal do Ceará, Departamento de Tecnologia de Alimentos, Av. Mister Hull 2977, Bloco 858, CEP 60356-000, Fortaleza, CE, Brazil.
authors.forename: Isabella Montenegro
authors.initials: IM
authors.lastname: Brasil
authors.affiliation: Universidade de São Paulo (USP), Faculdade de Ciências Farmacêuticas, Departamento de Alimentos e Nutrição Experimental, CEP 05508-000, São Paulo, SP, Brazil.
authors.forename: Jorge
authors.initials: J
authors.lastname: Mancini Filho
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D002374:Catalase / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry*; D005979:Glutathione Peroxidase / Q000378:metabolism*; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D010084:Oxidation-Reduction; D018384:Oxidative Stress; D051381:Rats; D013482:Superoxide Dismutase / Q000378:metabolism*
chemical_list: D000975:Antioxidants; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase
keywords: Antioxidant defense system; Catalase; Glutathione peroxidase; In vivo assay; Oxidative stress; Superoxide dismutase; Total antioxidant capacity; Tropical fruits