title: [Home parenteral nutrition in elderly patients with cancer: an observational prospective study].
abstract: Malnutrition is a bad prognostic factor that reduces the quality of life (QoL) in patients with cancer. The objective was to assess the impact of home parenteral nutrition (HPN) on the QoL of elderly malnourished patients with cancer. This French prospective observational study included patients, aged 70 years or older, with cancer, for whom HPN was prescribed for at least 14 days. The patient, the physician and a family member or home caregiver had to fill in a questionnaire at inclusion and 28 days later. Included patients (n = 221) were mainly suffering from a digestive cancer. After HPN intake, improved weight was noticed in 68% and 14% of patients had reached the target weight. Improved global QoL was reported in 59% of patients. Physicians noticed a significant improvement for the same compounds. These results suggest a benefit of the HPN on the nutritional status and QoL in elderly patients with cancer. Further controlled randomised trials are needed to prove the benefit of HPN in the routine management of these patients.
authors.affiliation: Polyclinique privée, Service d'oncologie, 1, rue Robert-Debré, 41260 La Chaussée-Saint-Victor, France.
authors.forename: Patrick
authors.initials: P
authors.lastname: Seys
authors.affiliation: Département scientifique, ClinSearch, 1, avenue de l'Égalité, 92220 Bagneux, France.
authors.forename: Abir
authors.initials: A
authors.lastname: Tadmouri
authors.affiliation: Département de gastroentérologie et nutrition clinique, Val d'Aurelle, 208, avenue des Apothicaires, 34298 Montpellier cedex 5, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Senesse
authors.affiliation: Centre Frédéric-Joliot, 7, rue de l'Abreuvoir, 76000 Rouen, France.
authors.forename: Abderraouf
authors.initials: A
authors.lastname: Radji
authors.affiliation: Centre d'oncologie et radiothérapie, 14, allées Paulmy, 64100 Bayonne, France.
authors.forename: Maciej
authors.initials: M
authors.lastname: Rotarski
authors.affiliation: Hôpital Antoine-Béclère, Service d'hépatogastroentérologie, 157, rue de la Porte-de-Trivaux, 92140 Clamart, France.
authors.forename: Axel
authors.initials: A
authors.lastname: Balian
authors.affiliation: Hôpital Henri-Mondor, Service d'oncologie, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Culine
authors.affiliation: CLCC, 3, rue de la porte-de-l'Hôpital, 67000 Strasbourg, France.
authors.forename: Patrick
authors.initials: P
authors.lastname: Dufour
authors.affiliation: Hospices Civils de Lyon, Service de nutrition clinique intensive, 103, Grande-Rue de la Croix-Rousse, 69317 Lyon cedex 04, France.
authors.forename: Cécile
authors.initials: C
authors.lastname: Chambrier
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004067:Digestive System Neoplasms / Q000150:complications; D005260:Female; D005602:France; D006801:Humans; D008297:Male; D044342:Malnutrition / Q000209:etiology / Q000628:therapy*; D009369:Neoplasms / Q000150:complications*; D009752:Nutritional Status; D009959:Oropharyngeal Neoplasms / Q000150:complications; D016331:Parenteral Nutrition, Home / Q000009:adverse effects; D011446:Prospective Studies; D011788:Quality of Life; D012142:Respiratory Tract Neoplasms / Q000150:complications; D011795:Surveys and Questionnaires; D015430:Weight Gain
keywords: cancer; elderly patients; home parenteral nutrition; nutritional status; quality of life