title: Effect of herbal therapy to intensity chemotherapy-induced nausea and vomiting in cancer patients.
abstract: BACKGROUND
  Chemotherapy-induced nausea and vomiting are the most important complications for cancer patients as its prevalence has been reported to be about 54-96 percent. ginger has been used for medicinal purposes including nausea and vomiting in traditional Persian, Chinese and Indian pharmacopoeia.
  
  
  OBJECTIVE
  The objective of this study was to evaluate the efficacy of complimentary ginger among cancer patients experiencing nausea and vomiting.
  
  
  METHODS
  A randomized cross-over clinical trial was carried out on patients under chemotherapy treatment for at least 2 episodes of chemotherapy and at least 2 episodes of previous experience of nausea and vomiting. Subjects of this study received 2 different complementary regimes with 250mg ginger capsule in regime A and placebo capsule in regime B. subjects of the study were crossed over to receive the other regime during the two cycles of chemotherapy.
  
  
  RESULTS
  Findings of the study indicated that subjects receiving ginger showed significant reduction in frequency and intensity of nausea and vomiting compared to placebo receiving subjects.
  
  
  CONCLUSIONS
  According to finding of this study, in accordance to most of other researches, ginger is an effective agent to reduce chemotherapy-induced nausea and vomiting. However, there are some researches supporting ginger as a moderate antiemetic agent among cancerous patients under chemotherapy.
authors.affiliation: School of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, IR Iran.
authors.forename: Akram Sadat
authors.initials: AS
authors.lastname: Montazeri
authors.affiliation: Clinical Research Development Center, Qom University of Medical Sciences, Qom, IR Iran.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Raei
authors.affiliation: School of Nursing and Midwifery, Guilan University of Medical Sciences, Rasht, IR Iran.
authors.forename: Atefeh
authors.initials: A
authors.lastname: Ghanbari
authors.affiliation: School of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, IR Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Dadgari
authors.affiliation: School of Pharmacy, Tehran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Azam Sadat
authors.initials: AS
authors.lastname: Montazeri
authors.affiliation: School of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, IR Iran.
authors.forename: Azam
authors.initials: A
authors.lastname: Hamidzadeh
keywords: Cancer; Chemotherapy; Ginger; Herbal Therapy; Nausea; Vomiting