title: Teicoplanin-induced hepatocellular liver injury: a case report and literature review of 17 cases in mainland China.
abstract: We report a rare case of teicoplanin- induced hepatocellular liver injury in a 49-year-old male patient with pulmonary infection. Liver function returned to normal after drug withdrawal. We reviewed 17 case reports of adverse reactions associated with teicoplanin in mainland China and found that (1) among all patients 15 were male and 53% of patients were elderly, (2) red man syndrome, anaphylactic shock and symptom of hematological system were common, (3) red man syndrome, excitement and anaphylactic shock related to teicoplanin reported in mainland China were very rare abroad. The clinician should be vigilant about the adverse reaction of teicoplanin and further studies are needed to explore the pathogenesis.
authors.forename: Jian-Xiang
authors.initials: JX
authors.lastname: Xie
authors.forename: Ji-Fu
authors.initials: JF
authors.lastname: Wei
authors.forename: Ling
authors.initials: L
authors.lastname: Meng
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000209:etiology*; D002681:China; D057915:Drug Substitution; D005260:Female; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D012141:Respiratory Tract Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D017334:Teicoplanin / Q000009:adverse effects*
chemical_list: D000900:Anti-Bacterial Agents; D017334:Teicoplanin