title: Determination of the pore size distribution of high-performance liquid chromatography stationary phases via inverse size exclusion chromatography.
abstract: Stationary phases in liquid chromatography exhibit quite different pore structures. Whereas most of the fully porous packing materials possess a narrow pore size distribution, core-shell particles are usually of rather wide pore size distribution. Recently a novel theory of size exclusion chromatography was introduced to model the effect of pore size distribution. The molecular theory of chromatography allows taking into account the kinetics of the pore ingress and egress processes, the heterogeneity of the pore sizes and polymer polydispersity as well. The novel model was applied to inverse size exclusion chromatography data. In this study, we have determined the actual pore size distribution of a number of HPLC stationary phases. Our results agree well with the results obtained with the model introduced by Knox and Scott.
authors.affiliation: Department of Analytical and Environmental Chemistry and Szentágothai Research Center, University of Pécs, Ifjúság útja 6, H-7624 Pécs, Hungary.
authors.forename: Ivett
authors.initials: I
authors.lastname: Bacskay
authors.affiliation: MTA-PTE Molecular Interactions in Separation Science Research Group, Ifjúság útja 6, H-7624 Pécs, Hungary.
authors.forename: Annamária
authors.initials: A
authors.lastname: Sepsey
authors.affiliation: Department of Analytical and Environmental Chemistry and Szentágothai Research Center, University of Pécs, Ifjúság útja 6, H-7624 Pécs, Hungary; MTA-PTE Molecular Interactions in Separation Science Research Group, Ifjúság útja 6, H-7624 Pécs, Hungary. Electronic address: felinger@ttk.pte.hu.
authors.forename: Attila
authors.initials: A
authors.lastname: Felinger
mesh_terms: D002850:Chromatography, Gel / Q000295:instrumentation / Q000379:methods* / Q000592:standards; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation / Q000379:methods* / Q000592:standards; D007700:Kinetics; D008962:Models, Theoretical; D011137:Polystyrenes / Q000737:chemistry; D016062:Porosity; D012015:Reference Standards; D013269:Stochastic Processes
chemical_list: D011137:Polystyrenes
keywords: Inverse size exclusion chromatography; Pore size distribution; Stationary phase; Stochastic theory