title: Remineralization of mechanical loaded resin-dentin interface: a transitional and synchronized multistep process.
abstract: This study evaluated the ability of different in vitro mechanical loading tests to promote new mineral formation at bonded dentin interfaces. This research demonstrated a sequential transition in the dentin remineralizing procedure through the analysis of the mineral and matrix gradients. Mechanical loading in phosphoric acid (PA)-treated samples promoted a generalized increases in relative presence of minerals, crystallinity, ratio of phosphate peaks and a decrease in the gradient of mineral content. The organic component showed, in general terms, an increase in crosslinking. [Formula: see text]-helices incremented in sine and square waveform loading. In EDTA + SB specimens, the relative mineral concentration incremented when loading in hold, in general. Nonuniform parameters of Bis-GMA and adhesive penetration were encountered in both groups. PA + SB promoted the highest dentin mineralization degree when loading in square, based on the increase in the relative presence of minerals and crystallinity. EDTA + SB produced any advance crystallographic maturity at the interface. High crosslinking parameters and conformational changes in proteins in PA-treated specimens indicated, indirectly, that the first remineralization is intrafibrillar.
authors.affiliation: Faculty of Dentistry, Dental Materials Section, University of Granada, Colegio Máximo de Cartuja s/n, 18071 , Granada, Spain, toledano@ugr.es.
authors.forename: Manuel
authors.initials: M
authors.lastname: Toledano
authors.forename: Fátima S
authors.initials: FS
authors.lastname: Aguilera
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Cabello
authors.forename: Raquel
authors.initials: R
authors.lastname: Osorio
mesh_terms: D000328:Adult; D001840:Dental Bonding; D003738:Dental Cements / Q000494:pharmacology; D003804:Dentin / Q000737:chemistry* / Q000187:drug effects; D004492:Edetic Acid; D006801:Humans; D010756:Phosphoric Acids / Q000494:pharmacology; D012117:Resins, Synthetic / Q000494:pharmacology*; D013059:Spectrum Analysis, Raman; D013314:Stress, Mechanical; D013499:Surface Properties; D014089:Tooth Remineralization / Q000379:methods*; D055815:Young Adult
chemical_list: D003738:Dental Cements; D010756:Phosphoric Acids; D012117:Resins, Synthetic; D004492:Edetic Acid; C030242:phosphoric acid