title: [Aspects seroepidemiological studies on Q fever in unvaccinated dairy cattle herds].
abstract: Q fever is a zoonosis distributed worldwide and important in human as well as in veterinary medicine in Germany. In Baden-Wurttemberg, the pathogen is endemic. Usually Q fever is associated with infected sheep flocks. In contrast, however, in the animal disease reporting system (TSN) 88.1% of all listed Q fever infections during the last 12 years have been registered in cattle. Accordingly, in Baden-Württemberg and Freudenstadt 78.3 and, respectively, 62.5% of the Q fever cases were from cattle. Long term studies on appearance of Coxiella burnetii in normal herds of cattle are missing. Increasing vaccination of cattle herds against Q fever with the vaccine approved in Germany (no marker vaccine) complicates the future opportunities to gain data from serological studies. In the present study, a total of 1640 bovine sera taken from unvaccinated, clini- tion against C burnetii for analysis and comparison. The results show, depending on the test, a seroprevalence of 4.3% to 7.4%. Seasonal comparison revealed a significant increase of up to 9%.The month with the highest seroprevalence aver aged over three years was June with a prevalence of 24.7%. Overall, the findings of this study demonstrate that even the high number of entries does not fully capture the true prevalence of Q fever in cattle herds.
authors.forename: Angela
authors.initials: A
authors.lastname: Hilbert
authors.forename: Irena
authors.initials: I
authors.lastname: Blaha
authors.forename: Andreas
authors.initials: A
authors.lastname: Fröhlich
authors.forename: Edmund
authors.initials: E
authors.lastname: Hensler
authors.forename: Peter
authors.initials: P
authors.lastname: Reith
authors.forename: Klaus
authors.initials: K
authors.lastname: Henning
authors.forename: Franz J
authors.initials: FJ
authors.lastname: Conraths
authors.forename: Thomas
authors.initials: T
authors.lastname: Miller
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000276:immunology; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology / Q000276:immunology; D016997:Coxiella burnetii / Q000276:immunology; D003612:Dairying; D005858:Germany / Q000453:epidemiology; D011778:Q Fever / Q000453:epidemiology / Q000276:immunology / Q000662:veterinary; D016036:Seroepidemiologic Studies; D014611:Vaccination
chemical_list: D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines