title: Percutaneous closure of patent foramen ovale with Atriasept II device in nickel allergic patients.
abstract: There are concerns about percutaneous closure of patent foramen ovale (PFO) using nitinol-alloys devices in patients with nickel hypersensitivity. We describe our experience with Atriasept II (Cardia Eagan, Minnesota, USA) used in four patients with known nickel allergy. No intraprocedural or in-hospital adverse events occurred. The follow-up was negative for allergic manifestations, without complications, as assessed by echocardiography. Because of the risk of adverse outcomes in nickel-allergic patients, devices with higher biocompatibility, low-profile, and low nickel content should be preferred in cases of known hypersensitivity. Atriasept II, containing less metallic material, appears to be a safe option in allergic patients undergoing PFO closure.
authors.affiliation: Department of Cardiovascular Disease, Tor Vergata University of Rome, Rome, Italy.
authors.forename: Valeria
authors.initials: V
authors.lastname: Cammalleri
authors.forename: Gian Paolo
authors.initials: GP
authors.lastname: Ussia
authors.forename: Massimo
authors.initials: M
authors.lastname: Marchei
authors.forename: Saverio
authors.initials: S
authors.lastname: Muscoli
authors.forename: Domenico
authors.initials: D
authors.lastname: Sergi
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Macrini
authors.forename: Francesco
authors.initials: F
authors.lastname: Romeo
mesh_terms: D000328:Adult; D000497:Alloys / Q000009:adverse effects*; D006328:Cardiac Catheterization / Q000379:methods; D004342:Drug Hypersensitivity / Q000209:etiology / Q000517:prevention & control*; D005260:Female; D005471:Fluoroscopy; D054092:Foramen Ovale, Patent / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009532:Nickel / Q000009:adverse effects; D011474:Prosthesis Design; D055989:Septal Occluder Device / Q000009:adverse effects*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000497:Alloys; C013616:nitinol; D009532:Nickel