title: Current aims and challenges associated with cervical cancer prevention.
abstract: This chapter will review the current modalities available to the clinician to screen for premalignant and malignant cervical lesions, which cast a broad net. The majority who test positive are not destined to suffer from or die from cervical cancer. Many who undergo screening and are triaged are young and subsequently face a number of aggressive and destructive therapies. This calls into question whether higher-risk patients should be managed more aggressively than an average-risk patient represented in the study population used to craft the guidelines.
authors.affiliation: *Southern California Permanente Medical Group, Kaiser Permanente, Anaheim, California †Department of Obstetrics and Gynecology, University of California, Irvine, California ‡Department of Gynecologic Oncology, University of California Irvine School of Medicine, Irvine, California §Washington University in St. Louis, St Louis, Missouri.
authors.forename: Neal M
authors.initials: NM
authors.lastname: Lonky
authors.forename: Kristine R
authors.initials: KR
authors.lastname: Penner
authors.forename: Justin T
authors.initials: JT
authors.lastname: Diedrich
mesh_terms: D052685:Alphapapillomavirus; D018450:Disease Progression; D005260:Female; D006801:Humans; D030361:Papillomavirus Infections / Q000517:prevention & control; D053918:Papillomavirus Vaccines / Q000627:therapeutic use; D011322:Primary Prevention; D018570:Risk Assessment; D055502:Secondary Prevention; D002578:Uterine Cervical Dysplasia; D002583:Uterine Cervical Neoplasms / Q000517:prevention & control* / Q000821:virology
chemical_list: D053918:Papillomavirus Vaccines