title: RHOA mutations in peripheral T cell lymphoma.
abstract: Peripheral T cell lymphomas are rare but aggressive non-Hodgkin lymphomas derived from mature T lymphocytes or natural killer (NK) cells. New studies identify recurrent dominant-negative mutation of the RHOA GTPase gene in these lymphomas.
authors.affiliation: VIB Center for the Biology of Disease and the KU Leuven Center for Human Genetics, Leuven, Belgium.
authors.forename: Jan
authors.initials: J
authors.lastname: Cools
mesh_terms: D020868:Gene Silencing; D006801:Humans; D016399:Lymphoma, T-Cell / Q000235:genetics*; D008958:Models, Molecular; D020125:Mutation, Missense / Q000235:genetics*; D015398:Signal Transduction / Q000235:genetics*; D020742:rhoA GTP-Binding Protein / Q000235:genetics*
chemical_list: C066737:RHOA protein, human; D020742:rhoA GTP-Binding Protein