title: Probiotic 'glow of health': it's more than skin deep.
abstract: Radiant skin and hair are universal indicators of good health. It was recently shown that feeding of probiotic bacteria to aged mice rapidly induced youthful vitality characterised by thick lustrous skin and hair, and enhanced reproductive fitness, not seen in untreated controls. Probiotic-treated animals displayed integrated immune and hypothalamic-pituitary outputs that were isolated mechanistically to microbe-induced anti-inflammatory interleukin-10 and neuropeptide hormone oxytocin. In this way, probiotic microbes interface with mammalian physiological underpinnings to impart superb physical and reproductive fitness displayed as radiant and resilient skin and mucosae, unveiling novel strategies for integumentary health.
authors.affiliation: Division of Comparative Medicine, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
authors.forename: S E
authors.initials: SE
authors.lastname: Erdman
authors.affiliation: Division of Comparative Medicine, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA Faculty of Veterinary Medicine, Laboratory of Pathology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
authors.forename: T
authors.initials: T
authors.lastname: Poutahidis
mesh_terms: D000818:Animals; D007378:Interleukins / Q000378:metabolism*; D051379:Mice; D010121:Oxytocin / Q000378:metabolism*; D019936:Probiotics / Q000008:administration & dosage*; D012871:Skin Diseases / Q000517:prevention & control*; D012879:Skin Physiological Phenomena
chemical_list: D007378:Interleukins; D010121:Oxytocin
keywords: Lactobacillus reuteri; inflammation; probiotics; regulatory T cells