title: Fatal Fusarium solani infection after stem cell transplant for aplastic anemia.
abstract: Fusarium is a saprophytic and opportunistic pathogen that can cause local tissue infection and life-threatening systemic infection. Systemic infection is rare and is observed primarily in immunocompromised patients. The early diagnosis is difficult, and the optimal treatment is unclear. However, the mortality is high. A 21-year-old man with aplastic anemia was treated with an allogeneic stem cell transplant. He developed fatal Fusarium solani infection. Fusarium species may be overlooked pathogenic fungi in immunocompromised patients, especially bone marrow transplant recipients.
authors.affiliation: From the Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hu Bei, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Cheng
authors.forename: Fankai
authors.initials: F
authors.lastname: Meng
authors.forename: Donghua
authors.initials: D
authors.lastname: Zhang
mesh_terms: D000741:Anemia, Aplastic / Q000175:diagnosis / Q000601:surgery*; D000935:Antifungal Agents / Q000627:therapeutic use; D017809:Fatal Outcome; D060585:Fusariosis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005670:Fusarium / Q000302:isolation & purification*; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects; D008297:Male; D009887:Ophthalmoscopy; D009894:Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D033581:Stem Cell Transplantation / Q000009:adverse effects*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000935:Antifungal Agents; D007166:Immunosuppressive Agents