title: Comparative chemical study and cytotoxic activity of Uvariodendron angustifolium essential oils from Benin.
abstract: This study aimed to compare the chemical composition of volatile extracts obtained by hydrodistillation of leaves, stems, bark and roots of Uvariodendron angustifolium (Engl. & Diels) R. E. Fries. The essential oils, obtained with yields between 0.12 and 0.66%, were analyzed by GC/FID and GC/MS. A great variability in the chemical composition was observed depending on the plant part treated. The essential oils obtained from leaves and stems contained mainly neral (29.7-30.5%) and geranial (42.9-47.3%), while methyl eugenol was the major component of the volatile extracts from bark (68.3%) and roots (85.3%). Interesting cytotoxic properties of these essential oils on human breast cancer cells MCF-7 were demonstrated.
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Noudogbessi
authors.forename: Magali
authors.initials: M
authors.lastname: Gary-Bobo
authors.forename: Aristide
authors.initials: A
authors.lastname: Adomou
authors.forename: Elvis
authors.initials: E
authors.lastname: Adjalian
authors.forename: Guy Alain
authors.initials: GA
authors.lastname: Alitonou
authors.forename: Félicien
authors.initials: F
authors.lastname: Avlessi
authors.forename: Marcel
authors.initials: M
authors.lastname: Garcia
authors.forename: Dominique C K
authors.initials: DC
authors.lastname: Sohounhloue
authors.forename: Chantal
authors.initials: C
authors.lastname: Menut
mesh_terms: D029061:Annonaceae / Q000737:chemistry*; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D001541:Benin; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D061986:MCF-7 Cells; D009822:Oils, Volatile / Q000032:analysis* / Q000494:pharmacology*; D010936:Plant Extracts / Q000032:analysis
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D009822:Oils, Volatile; D010936:Plant Extracts