title: Indoor molds and lung function in healthy adults.
abstract: BACKGROUND
  Indoor mold exposure is common worldwide and constitutes an important health problem. There are very few studies assessing the relation between mold exposure and lung function levels among non-asthmatic adults. Our objective was to assess the relations between dampness and mold exposures at home and at work and lung function. In particular, we elaborated the importance of different exposure indicators.
  
  
  METHODS
  In a population-based study, 269 non-asthmatic adults from South Finland answered a questionnaire on indoor dampness and mold exposures at home or at work and other factors potentially influencing lung function, and performed spirometry. Multiple linear regression model was applied to study the relations between exposures and spirometric lung function levels.
  
  
  RESULTS
  In linear regression adjusting for confounding, FEV1 level was reduced on average 200 ml related to mold odor at home (effect estimate -0.20, 95% CI -0.60 to 0.21) and FVC level was reduced on average 460 ml (-0.46, -0.95 to 0.03) respectively. Exposure to mold odor at home or at work or both was related to reduced FEV1 (-0.15, -0.42 to 0.12) and FVC (-0.22, -0.55 to 0.11) levels. Women had on average 510 ml reduced FEV1 levels (-0.51, -1.0 to 0.03) and 820 ml reduced FVC levels (-0.82, -1.4 to -0.20) related to mold odor exposure at home.
  
  
  CONCLUSIONS
  Mold odor exposure was related to lower lung function levels among non-asthmatic adults, especially among women.
authors.affiliation: Center for Environmental and Respiratory Health Research, University of Oulu, Oulu, Finland; Respiratory Medicine Unit, Institute of Clinical Medicine, University of Oulu, Oulu, Finland; Respiratory Medicine Unit, Oulu University Hospital, Oulu, Finland.
authors.forename: Samu
authors.initials: S
authors.lastname: Hernberg
authors.affiliation: Center for Environmental and Respiratory Health Research, University of Oulu, Oulu, Finland; Faculty of Public Health, Thammasat University, Thailand.
authors.forename: Penpatra
authors.initials: P
authors.lastname: Sripaiboonkij
authors.affiliation: Center for Environmental and Respiratory Health Research, University of Oulu, Oulu, Finland.
authors.forename: Reginald
authors.initials: R
authors.lastname: Quansah
authors.affiliation: Center for Environmental and Respiratory Health Research, University of Oulu, Oulu, Finland; Respiratory Medicine Unit, Oulu University Hospital, Oulu, Finland; Public Health, Institute of Health Sciences, University of Oulu, Oulu, Finland. Electronic address: jouni.jaakkola@oulu.fi.
authors.forename: Jouni J K
authors.initials: JJ
authors.lastname: Jaakkola
authors.affiliation: Center for Environmental and Respiratory Health Research, University of Oulu, Oulu, Finland; Respiratory Medicine Unit, Institute of Clinical Medicine, University of Oulu, Oulu, Finland; Respiratory Medicine Unit, Oulu University Hospital, Oulu, Finland.
authors.forename: Maritta S
authors.initials: MS
authors.lastname: Jaakkola
mesh_terms: D000328:Adult; D016902:Air Pollution, Indoor / Q000009:adverse effects* / Q000032:analysis; D003430:Cross-Sectional Studies; D005260:Female; D005541:Forced Expiratory Volume / Q000502:physiology*; D005658:Fungi; D006798:Housing; D006801:Humans; D006813:Humidity; D019570:Inhalation Exposure / Q000009:adverse effects / Q000032:analysis; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects / Q000032:analysis; D009812:Odorants; D012129:Respiratory Function Tests / Q000379:methods; D013147:Spirometry / Q000379:methods; D014797:Vital Capacity / Q000502:physiology*; D055815:Young Adult
keywords: Dampness; FEV(1); FVC; Lung function; Mold odor; Molds