title: Rhodium-catalyzed direct amination of arenes with nitrosobenzenes: a new route to diarylamines.
abstract: A Rh(III) -catalyzed addition of aryl CH bonds to nitrosobenzenes, followed by cleavage of the resulting hydroxylamines in situ, has been reported. Different directing groups, such as N-based heterocycles and ketoximes, can be used in this CH amination process, providing valuable diarylamines in excellent yields. Most importantly, this process provides a new method for attaching arylamine groups to aromatic rings.
authors.affiliation: Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203 (China), Fax: (+86) 21-50807288.
authors.forename: Juanjuan
authors.initials: J
authors.lastname: Du
authors.forename: Yaxi
authors.initials: Y
authors.lastname: Yang
authors.forename: Huijin
authors.initials: H
authors.lastname: Feng
authors.forename: Yuanchao
authors.initials: Y
authors.lastname: Li
authors.forename: Bing
authors.initials: B
authors.lastname: Zhou
mesh_terms: D000586:Amination; D000814:Aniline Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D006860:Hydrogen Bonding; D015394:Molecular Structure; D009603:Nitroso Compounds / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*
chemical_list: D000814:Aniline Compounds; D009603:Nitroso Compounds; D012238:Rhodium; C012456:nitrosobenzene
keywords: CH activation; diarylamines; isatin; nitrosobenzenes; rhodium