title: Management of non-melanoma skin cancer in solid organ transplant recipients.
abstract: Non-melanoma skin cancer (NMSC) is the most frequent cancer observed in solid organ transplant recipients (SOTR). Early diagnosis, patient education, and modification of immunosuppression are effective measures for reduction of NMSC incidence. Many risk factors have been identified, including age at transplantation, fair skin, type of immunosuppressive drugs, cumulative sun exposure, viral infections, and various genetic markers. Skin self-examination and photoprotection should be encouraged in all transplanted patients. Long-term skin surveillance, early diagnosis and aggressive treatment of any suspicious lesion, reduction of immunosuppressive therapy, and conversion to mammalian target-of-rapamycin (m-TOR) inhibitors can be also effective measures for reduction of NMSC incidence.
authors.affiliation: Department of Medicine, University of Rome, Tor Vergata, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Specchio
authors.affiliation: Department of Medicine, University of Rome, Tor Vergata, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Saraceno
authors.affiliation: Department of Medicine, University of Rome, Tor Vergata, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Chimenti
authors.affiliation: Department of Health Sciences, University of Catanzaro Magna Græcia, Catanzaro, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Nistico
mesh_terms: D002280:Basal Cell Carcinoma / Q000453:epidemiology / Q000209:etiology / Q000276:immunology / Q000517:prevention & control*; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000209:etiology / Q000276:immunology / Q000517:prevention & control*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D015994:Incidence; D016377:Organ Transplantation; D010353:Patient Education as Topic; D012307:Risk Factors; D012878:Skin Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000276:immunology / Q000517:prevention & control*; D014466:Ultraviolet Rays / Q000009:adverse effects
chemical_list: D007166:Immunosuppressive Agents