title: Molecular characterization of an Australian serotype 1 Streptococcus pneumoniae outbreak.
abstract: Serotype 1 Streptococcus pneumoniae is a cause of invasive pneumococcal disease (IPD) worldwide and has been associated with IPD outbreaks, while carriage is rarely detected in healthy adults or children. This study details an Australian multi-state and territory outbreak of serotype 1 S. pneumoniae IPD between 2010 and 2012. Molecular characterization demonstrated the outbreak was largely due to the clonal expansion of sequence type 306, MLVA type 261 S. pneumoniae serotype 1.
authors.affiliation: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
authors.forename: M
authors.initials: M
authors.lastname: Staples
authors.affiliation: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
authors.forename: R M A
authors.initials: RM
authors.lastname: Graham
authors.affiliation: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
authors.forename: A V
authors.initials: AV
authors.lastname: Jennison
authors.affiliation: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
authors.forename: L
authors.initials: L
authors.lastname: Ariotti
authors.affiliation: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
authors.forename: V
authors.initials: V
authors.lastname: Hicks
authors.affiliation: Centre for Disease Control, Department of Health, Northern Territory,Australia.
authors.forename: H
authors.initials: H
authors.lastname: Cook
authors.affiliation: Centre for Disease Control, Department of Health, Northern Territory,Australia.
authors.forename: V
authors.initials: V
authors.lastname: Krause
authors.affiliation: Communicable Disease Control Directorate, Public Health Division, Department of Health, Western Australia,Australia.
authors.forename: C
authors.initials: C
authors.lastname: Giele
authors.affiliation: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
authors.forename: H V
authors.initials: HV
authors.lastname: Smith
mesh_terms: D000293:Adolescent; D000328:Adult; D001315:Australia / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks / Q000706:statistics & numerical data*; D006801:Humans; D008875:Middle Aged; D015233:Models, Statistical; D017720:Molecular Epidemiology; D011008:Pneumococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D013296:Streptococcus pneumoniae / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D055815:Young Adult