title: Antimicrobial susceptibility of Escherichia coli F4, Pasteurella multocida, and Streptococcus suis isolates from a diagnostic veterinary laboratory and recommendations for a surveillance system.
abstract: Antimicrobial susceptibility data on Escherichia coli F4, Pasteurella multocida, and Streptococcus suis isolates from Ontario swine (January 1998 to October 2010) were acquired from a comprehensive diagnostic veterinary laboratory in Ontario, Canada. In relation to the possible development of a surveillance system for antimicrobial resistance, data were assessed for ease of management, completeness, consistency, and applicability for temporal and spatial statistical analyses. Limited farm location data precluded spatial analyses and missing demographic data limited their use as predictors within multivariable statistical models. Changes in the standard panel of antimicrobials used for susceptibility testing reduced the number of antimicrobials available for temporal analyses. Data consistency and quality could improve over time in this and similar diagnostic laboratory settings by encouraging complete reporting with sample submission and by modifying database systems to limit free-text data entry. These changes could make more statistical methods available for disease surveillance and cluster detection.
authors.affiliation: Department of Population Medicine (Glass-Kaastra, Pearl, Reid-Smith, S. McEwen), Department of Pathobiology (Reid-Smith), and Animal Health Laboratory (B. McEwen, Slavic, Fairles), University of Guelph, Guelph, Ontario N1G 2W1; Laboratory for Foodborne Zoonoses, Public Health Agency of Canada, 160 Research Lane, Guelph, Ontario N1G B52 (Reid-Smith).
authors.forename: Shiona K
authors.initials: SK
authors.lastname: Glass-Kaastra
authors.affiliation: Department of Population Medicine (Glass-Kaastra, Pearl, Reid-Smith, S. McEwen), Department of Pathobiology (Reid-Smith), and Animal Health Laboratory (B. McEwen, Slavic, Fairles), University of Guelph, Guelph, Ontario N1G 2W1; Laboratory for Foodborne Zoonoses, Public Health Agency of Canada, 160 Research Lane, Guelph, Ontario N1G B52 (Reid-Smith).
authors.forename: David L
authors.initials: DL
authors.lastname: Pearl
authors.affiliation: Department of Population Medicine (Glass-Kaastra, Pearl, Reid-Smith, S. McEwen), Department of Pathobiology (Reid-Smith), and Animal Health Laboratory (B. McEwen, Slavic, Fairles), University of Guelph, Guelph, Ontario N1G 2W1; Laboratory for Foodborne Zoonoses, Public Health Agency of Canada, 160 Research Lane, Guelph, Ontario N1G B52 (Reid-Smith).
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Reid-Smith
authors.affiliation: Department of Population Medicine (Glass-Kaastra, Pearl, Reid-Smith, S. McEwen), Department of Pathobiology (Reid-Smith), and Animal Health Laboratory (B. McEwen, Slavic, Fairles), University of Guelph, Guelph, Ontario N1G 2W1; Laboratory for Foodborne Zoonoses, Public Health Agency of Canada, 160 Research Lane, Guelph, Ontario N1G B52 (Reid-Smith).
authors.forename: Beverly
authors.initials: B
authors.lastname: McEwen
authors.affiliation: Department of Population Medicine (Glass-Kaastra, Pearl, Reid-Smith, S. McEwen), Department of Pathobiology (Reid-Smith), and Animal Health Laboratory (B. McEwen, Slavic, Fairles), University of Guelph, Guelph, Ontario N1G 2W1; Laboratory for Foodborne Zoonoses, Public Health Agency of Canada, 160 Research Lane, Guelph, Ontario N1G B52 (Reid-Smith).
authors.forename: Durda
authors.initials: D
authors.lastname: Slavic
authors.affiliation: Department of Population Medicine (Glass-Kaastra, Pearl, Reid-Smith, S. McEwen), Department of Pathobiology (Reid-Smith), and Animal Health Laboratory (B. McEwen, Slavic, Fairles), University of Guelph, Guelph, Ontario N1G 2W1; Laboratory for Foodborne Zoonoses, Public Health Agency of Canada, 160 Research Lane, Guelph, Ontario N1G B52 (Reid-Smith).
authors.forename: Scott A
authors.initials: SA
authors.lastname: McEwen
authors.affiliation: Department of Population Medicine (Glass-Kaastra, Pearl, Reid-Smith, S. McEwen), Department of Pathobiology (Reid-Smith), and Animal Health Laboratory (B. McEwen, Slavic, Fairles), University of Guelph, Guelph, Ontario N1G 2W1; Laboratory for Foodborne Zoonoses, Public Health Agency of Canada, 160 Research Lane, Guelph, Ontario N1G B52 (Reid-Smith).
authors.forename: Jim
authors.initials: J
authors.lastname: Fairles
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004926:Escherichia coli / Q000145:classification / Q000187:drug effects*; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary; D007753:Laboratories; D009864:Ontario / Q000453:epidemiology; D010326:Pasteurella Infections / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary; D016979:Pasteurella multocida / Q000187:drug effects*; D011159:Population Surveillance; D013290:Streptococcal Infections / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary; D017011:Streptococcus suis / Q000187:drug effects*; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology / Q000382:microbiology*; D014730:Veterinary Medicine
chemical_list: D000900:Anti-Bacterial Agents