title: Direct C-H bond arylation of (benzo)oxazoles with aryl chlorides catalyzed by N-heterocyclic carbene-palladium(II)-1-methylimidazole complex.
abstract: The direct C-H bond arylation of (benzo)oxazoles with aryl chlorides was achieved catalyzed by a well-defined NHC-Pd(II)-Im complex. Under the optimal conditions, various aryl chlorides were successfully applied as the arylating reagents to achieve the 2-aryl (benzo)oxazoles in acceptable to high yields, providing a convenient and alternative method for the direct C-H bond arylation of (benzo)oxazoles and enriching the chemistry of the NHC-Pd(II) complex in organic synthesis.
authors.affiliation: College of Chemistry and Materials Engineering, Wenzhou University , Chashan University Town, Wenzhou, Zhejiang Province 325035, People's Republic of China.
authors.forename: Xiao-Bao
authors.initials: XB
authors.lastname: Shen
authors.forename: Yun
authors.initials: Y
authors.lastname: Zhang
authors.forename: Wen-Xin
authors.initials: WX
authors.lastname: Chen
authors.forename: Zheng-Kang
authors.initials: ZK
authors.lastname: Xiao
authors.forename: Ting-Ting
authors.initials: TT
authors.lastname: Hu
authors.forename: Li-Xiong
authors.initials: LX
authors.lastname: Shao
mesh_terms: D001583:Benzoxazoles / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D006843:Hydrocarbons, Chlorinated / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: D001583:Benzoxazoles; D006575:Heterocyclic Compounds, 3-Ring; D006843:Hydrocarbons, Chlorinated; D010165:Palladium