title: Biometry and intraocular lens power calculation results with a new optical biometry device: comparison with the gold standard.
abstract: OBJECTIVE
  To evaluate the agreement in axial length (AL), keratometry (K), anterior chamber depth (ACD) measurements; intraocular lens (IOL) power calculations; and predictability using a new partial coherence interferometry (PCI) optical biometer (AL-Scan) and a reference (gold standard) PCI optical biometer (IOLMaster 500).
  
  
  METHODS
  Service d'Ophtalmologie, Hopital Bicêtre, APHP Université, Paris, France.
  
  
  METHODS
  Evaluation of a diagnostic device.
  
  
  METHODS
  One eye of consecutive patients scheduled for cataract surgery was measured. Biometry was performed with the new biometer and the reference biometer. Comparisons were performed for AL, average K at 2.4 mm, ACD, IOL power calculations with the Haigis and SRK/T formulas, and postoperative predictability of the devices. A P value less than 0.05 was statistically significant.
  
  
  RESULTS
  The study enrolled 50 patients (mean age 72.6 years±4.2 SEM). There was a good correlation between biometers for AL, K, and ACD measurements (r=0.999, r=0.933, and r=0.701, respectively) and between IOL power calculation with the Haigis formula (r=0.972) and the SRK/T formula (r=0.981). The mean absolute error (MAE) in IOL power prediction was 0.42±0.08 diopter (D) with the new biometer and 0.44±0.08 D with the reference biometer. The MAE was 0.20 D with the Haigis formula and 0.19 with the SRK/T formula (P=.36).
  
  
  CONCLUSIONS
  The new PCI biometer provided valid measurements compared with the current gold standard, indicating that the new device can be used for IOL power calculations for routine cataract surgery.
  
  
  BACKGROUND
  No author has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: From the Service d'Ophtalmologie (Kaswin, Rousseau, Mgarrech, Barreau, Labetoulle), Hôpital Bicêtre, APHP, Université Paris Sud, Le Kremlin-Bicêtre and Laboratoire de Virologie Moléculaire et Structurale CNRS UPR 3296 (Rousseau, Labetoulle), Gif sur Yvette, France.
authors.forename: Godefroy
authors.initials: G
authors.lastname: Kaswin
authors.affiliation: From the Service d'Ophtalmologie (Kaswin, Rousseau, Mgarrech, Barreau, Labetoulle), Hôpital Bicêtre, APHP, Université Paris Sud, Le Kremlin-Bicêtre and Laboratoire de Virologie Moléculaire et Structurale CNRS UPR 3296 (Rousseau, Labetoulle), Gif sur Yvette, France.
authors.forename: Antoine
authors.initials: A
authors.lastname: Rousseau
authors.affiliation: From the Service d'Ophtalmologie (Kaswin, Rousseau, Mgarrech, Barreau, Labetoulle), Hôpital Bicêtre, APHP, Université Paris Sud, Le Kremlin-Bicêtre and Laboratoire de Virologie Moléculaire et Structurale CNRS UPR 3296 (Rousseau, Labetoulle), Gif sur Yvette, France.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Mgarrech
authors.affiliation: From the Service d'Ophtalmologie (Kaswin, Rousseau, Mgarrech, Barreau, Labetoulle), Hôpital Bicêtre, APHP, Université Paris Sud, Le Kremlin-Bicêtre and Laboratoire de Virologie Moléculaire et Structurale CNRS UPR 3296 (Rousseau, Labetoulle), Gif sur Yvette, France.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Barreau
authors.affiliation: From the Service d'Ophtalmologie (Kaswin, Rousseau, Mgarrech, Barreau, Labetoulle), Hôpital Bicêtre, APHP, Université Paris Sud, Le Kremlin-Bicêtre and Laboratoire de Virologie Moléculaire et Structurale CNRS UPR 3296 (Rousseau, Labetoulle), Gif sur Yvette, France. Electronic address: marc.labetoulle@bct.aphp.fr.
authors.forename: Marc
authors.initials: M
authors.lastname: Labetoulle
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D058452:Axial Length, Eye; D001699:Biometry / Q000295:instrumentation*; D005260:Female; D006801:Humans; D007368:Interferometry / Q000295:instrumentation; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D055095:Optics and Photonics; D018918:Phacoemulsification; D011446:Prospective Studies; D012029:Refraction, Ocular / Q000502:physiology; D015203:Reproducibility of Results