title: Discovering the power of single molecules.
abstract: Mechanical manipulations of single biological molecules have revealed highly dynamic and mechanical processes at the molecular level. Recent developments have permitted examination of the impact of torque on these processes and visualization of detailed molecular motions, enabling studies of increasingly complex systems. Here we highlight some recent important discoveries.
authors.affiliation: Department of Physics, Laboratory of Atomic and Solid State Physics, Cornell University, Ithaca, NY 14853, USA; Howard Hughes Medical Institute, Cornell University, Ithaca, NY 14853, USA.
authors.forename: Robert A
authors.initials: RA
authors.lastname: Forties
authors.affiliation: Department of Physics, Laboratory of Atomic and Solid State Physics, Cornell University, Ithaca, NY 14853, USA; Howard Hughes Medical Institute, Cornell University, Ithaca, NY 14853, USA. Electronic address: mwang@physics.cornell.edu.
authors.forename: Michelle D
authors.initials: MD
authors.lastname: Wang
mesh_terms: D001696:Biomechanical Phenomena; D004247:DNA / Q000737:chemistry* / Q000378:metabolism*; D004278:DNA, Superhelical / Q000737:chemistry / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000378:metabolism*; D020409:Molecular Motor Proteins / Q000378:metabolism; D019415:Torque; D014158:Transcription, Genetic
chemical_list: D004278:DNA, Superhelical; D004268:DNA-Binding Proteins; D020409:Molecular Motor Proteins; D004247:DNA