title: Resetting and entrainment of reentrant ventricular tachycardia associated with myocardial infarction.
abstract: Resetting and entrainment are specific responses to programmed stimulation that are useful in determining the mechanism of ventricular tachycardia (VT), localizing critical components of a reentrant circuit to guide ablation, determining how antiarrhythmic drugs affect the tachycardia, and developing antitachycardia pacing modalities. While resetting and entrainment have certain things in common, they differ significantly in the ability to characterize the properties of VT. Only resetting, which is the interaction of a single extrastimulus with the tachycardia, can characterize the properties of the VT itself. Entrainment assesses the effect of overdrive pacing on a reset circuit, not the VT itself. The terms for these techniques are often incorrectly used interchangeably. The present review details the characteristics and uses of both stimulation techniques.
authors.affiliation: Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts; Harvard-Thorndike Electrophysiology Institute and Arrhythmia Service, Beth Israel Deaconess Medical Center, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts. Electronic address: mjoseph2@bidmc.harvard.edu.
authors.forename: Mark E
authors.initials: ME
authors.lastname: Josephson
authors.affiliation: Cardiac Electrophysiology Laboratory, Grupo HM Hospitales, Philadelphia, Pennsylvania; University CEU San Pablo, Madrid, Spain.
authors.forename: Jesus
authors.initials: J
authors.lastname: Almendral
authors.affiliation: Perelman School of Medicine of the University of Pennsylvania, Philadelphia, Pennsylvania; University of Pennsylvania Health System, Philadelphia, Pennsylvania.
authors.forename: David J
authors.initials: DJ
authors.lastname: Callans
mesh_terms: D002304:Cardiac Pacing, Artificial / Q000379:methods*; D004562:Electrocardiography; D004594:Electrophysiology; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D009203:Myocardial Infarction / Q000503:physiopathology*; D017180:Tachycardia, Ventricular / Q000503:physiopathology*
keywords: Entrainment; Pacing; Reentry; Resetting; Tachycardia