title: Ligand-enabled γ-C-H olefination and carbonylation: construction of β-quaternary carbon centers.
abstract: Monoselective γ-C-H olefination and carbonylation of aliphatic acids has been accomplished by using a combination of a quinoline-based ligand and a weakly coordinating amide directing group. The reaction provides a new route for constructing richly functionalized all-carbon quaternary carbon centers at the β-position of aliphatic acids.
authors.affiliation: Department of Chemistry, The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
authors.forename: Suhua
authors.initials: S
authors.lastname: Li
authors.forename: Gang
authors.initials: G
authors.lastname: Chen
authors.forename: Chen-Guo
authors.initials: CG
authors.lastname: Feng
authors.forename: Wei
authors.initials: W
authors.lastname: Gong
authors.forename: Jin-Quan
authors.initials: JQ
authors.lastname: Yu
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D005227:Fatty Acids / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D011804:Quinolines / Q000737:chemistry*
chemical_list: D000475:Alkenes; D005227:Fatty Acids; D008024:Ligands; D011804:Quinolines; D002244:Carbon; C037219:quinoline