title: Angiolymphoid hyperplasia with eosinophilia of the orbit and ocular adnexa: report of 5 cases.
abstract: OBJECTIVE
  To report the clinical and histopathologic findings of ocular adnexal angiolymphoid hyperplasia with eosinophilia, an unusual but often misdiagnosed benign disorder.
  
  
  METHODS
  The ophthalmologic findings of angiolymphoid hyperplasia with eosinophilia with ocular adnexal involvement are variable and include eyelid swelling, ptosis, proptosis, and loss of vision. Imaging studies typically reveal a well-circumscribed mass in the orbit. The condition may resemble other diseases that involve the orbit and ocular adnexal tissue, such as lymphoma, hemangioma, sarcoidosis, and dermoid cyst. Histopathologic analysis reveals marked vascular proliferation with an accompanying inflammation composed of numerous eosinophils, lymphocytes, and plasma cells.
  
  
  CONCLUSIONS
  Angiolymphoid hyperplasia with eosinophilia is a rare disease that can affect the ocular adnexal tissue. The clinical presentation is often nonspecific; therefore, histopathologic studies are essential for diagnosis and subsequent management of this benign condition.
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison.
authors.forename: Amir A
authors.initials: AA
authors.lastname: Azari
authors.affiliation: Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Mozhgan R
authors.initials: MR
authors.lastname: Kanavi
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison2Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Mark
authors.initials: M
authors.lastname: Lucarelli
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison.
authors.forename: Vivian
authors.initials: V
authors.lastname: Lee
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison.
authors.forename: Ashley M
authors.initials: AM
authors.lastname: Lundin
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison.
authors.forename: Heather D
authors.initials: HD
authors.lastname: Potter
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison3McPherson Eye Research Institute, University of Wisconsin, Madison.
authors.forename: Daniel M
authors.initials: DM
authors.lastname: Albert
mesh_terms: D000328:Adult; D000369:Aged, 80 and over; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000175:diagnosis*; D001706:Biopsy; D002648:Child; D003937:Diagnosis, Differential; D005141:Eyelid Diseases / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009915:Orbit / Q000000981:diagnostic imaging / Q000473:pathology*; D009916:Orbital Diseases / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed