title: Multiple sclerosis in children.
abstract: Multiple sclerosis (MS) is the most important immune-mediated demyelinated disease of human which is typically the disease of young adults. A total of 4% to 5% of MS population are pediatric. Pediatric MS is defined as the appearance of MS before the age of sixteen. About 80% of the pediatric cases and nearly all adolescent onset patients present with attacks typical to adult MS. Approximately 97% to 99% of the affected children have relapsing-remitting MS, while 85% to 95% of the adults experience such condition. MS in children is associated with more frequent and severe relapses. Treatment is the same as adults. We aimed to review the epidemiology, etiology, clinical manifestations, and treatment of MS in children.
authors.affiliation: Associate Professor of Pediatric Neurology, Neonatal Research Center, Pediatrics Department, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Soroor
authors.initials: S
authors.lastname: Inaloo
authors.affiliation: Fellow of Pediatric ICU, Assistant Professor of Pediatrics, Neonatal Research Center, Pediatrics Department, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Saideh
authors.initials: S
authors.lastname: Haghbin
keywords: Children; Etiology; Multiple Sclerosis; Treatment