title: Multimodal label-free detection and discrimination for small molecules using a nanoporous resonator.
abstract: To detect chemical or biological threats, it is crucial that sensor devices can differentiate various target molecules. In general, each different sensing method has its own strengths and weaknesses due to their respective limitations. For example, although resonant sensors have high sensitivity, they are not able to discriminate target molecules. At the same time, although surface-enhanced Raman spectroscopy is a representative label-free detection method that can discriminate target molecules, its fabrication is often complex and expensive. Here we present a label-free multimodal nanoporous resonator-based system for small molecule detection and discrimination that combines the strengths of each of these sensing methods. Our approach is not only able to improve the sensitivity of the resonant sensor but it can also discriminate the target molecules. Furthermore, the fabrication process is swift (lasting <3 min) and convenient.
authors.affiliation: 1] Department of Control and Instrumentation Engineering, Korea University, Jochiwon 339-700, Republic of Korea [2].
authors.forename: Jinsung
authors.initials: J
authors.lastname: Park
authors.affiliation: 1] Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul 120-749, Republic of Korea [2] Active Polymer Center for Pattern Integration (APCPI), Yonsei University, Seoul 120-749, Republic of Korea [3].
authors.forename: Doyeon
authors.initials: D
authors.lastname: Bang
authors.affiliation: 1] Department of Mechanical Engineering, Korea University, Seoul 136-701, Republic of Korea [2].
authors.forename: Kuewhan
authors.initials: K
authors.lastname: Jang
authors.affiliation: 1] Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul 120-749, Republic of Korea [2] Active Polymer Center for Pattern Integration (APCPI), Yonsei University, Seoul 120-749, Republic of Korea.
authors.forename: Eunkyoung
authors.initials: E
authors.lastname: Kim
authors.affiliation: Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul 120-749, Republic of Korea.
authors.forename: Seungjoo
authors.initials: S
authors.lastname: Haam
authors.affiliation: Department of Mechanical Engineering, Korea University, Seoul 136-701, Republic of Korea.
authors.forename: Sungsoo
authors.initials: S
authors.lastname: Na
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D036103:Nanotechnology / Q000379:methods*; D016062:Porosity