title: Direct myocardial implantation of human embryonic stem cells in a dog model of Duchenne cardiomyopathy reveals poor cell survival in dystrophic tissue.
abstract: Duchenne muscular dystrophy is characterized by progressive muscle weakness and early death resulting from dystrophin deficiency. Spontaneous canine muscular disorders are interesting settings to evaluate the relevance of innovative therapies in human using pre-clinical trials.
authors.affiliation: CECS, I-Stem, AFM , Evry 91030 cedex, France.
authors.forename: W
authors.initials: W
authors.lastname: Habeler
authors.affiliation: INSERM, U955, Créteil , 94000, France ; Université Paris Est, Faculté de médecine, Créteil and Ecole Nationale Vétérinaire d'Alfort , 94000, France.
authors.forename: B
authors.initials: B
authors.lastname: Ghaleh
authors.affiliation: Université Paris Est, Ecole Nationale Vétérinaire d'Alfort, UPR de Neurobiologie , 94704 Maisons-Alfort, France.
authors.forename: I
authors.initials: I
authors.lastname: Barthelemy
authors.affiliation: CECS, I-Stem, AFM , Evry 91030 cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Plancheron
authors.affiliation: INSERM, U955, Créteil , 94000, France ; Université Paris Est, Faculté de médecine, Créteil and Ecole Nationale Vétérinaire d'Alfort , 94000, France.
authors.forename: A
authors.initials: A
authors.lastname: Bizé
authors.affiliation: INSERM, U955, Créteil , 94000, France ; Université Paris Est, Faculté de médecine, Créteil and Ecole Nationale Vétérinaire d'Alfort , 94000, France.
authors.forename: C
authors.initials: C
authors.lastname: Carlos-Sampedrano
authors.affiliation: INSERM, U955, Créteil , 94000, France ; Université Paris Est, Faculté de médecine, Créteil and Ecole Nationale Vétérinaire d'Alfort , 94000, France.
authors.forename: V
authors.initials: V
authors.lastname: Chetboul
authors.affiliation: INSERM, U955, Créteil , 94000, France ; Université Paris Est, Faculté de médecine, Créteil and Ecole Nationale Vétérinaire d'Alfort , 94000, France.
authors.forename: A
authors.initials: A
authors.lastname: Berdeaux
authors.affiliation: INSERM U633, Avenir Program, Embryonic Stem Cells and Cardiogenesis , Evry, France.
authors.forename: M
authors.initials: M
authors.lastname: Pucéat
authors.affiliation: INSERM U861, I-STEM, AFM , Evry 91030 cedex France ; UEVE U861, I-STEM, AFM , Evry 91030 cedex France.
authors.forename: M
authors.initials: M
authors.lastname: Peschanski
authors.affiliation: Université Paris Est, Ecole Nationale Vétérinaire d'Alfort, UPR de Neurobiologie , 94704 Maisons-Alfort, France.
authors.forename: S
authors.initials: S
authors.lastname: Blot
authors.affiliation: INSERM U861, I-STEM, AFM , Evry 91030 cedex France ; UEVE U861, I-STEM, AFM , Evry 91030 cedex France.
authors.forename: C
authors.initials: C
authors.lastname: Monville
keywords: Duchenne Muscular Dystrophy; Golden Retriever Muscular Dystrophy; Human Embryonic Stem Cells; Transplantation