title: (DHQ)2AQN-catalyzed asymmetric substitution of isatin-derived hydrazones with O-Boc-protected Morita-Baylis-Hillman adducts: A strategy for synthesizing enantioenriched azo compounds incorporating an oxindole scaffold.
abstract: The first example for the preparation of enantioenriched azo compounds from hydrazones and Morita-Baylis-Hillman adducts has been developed, affording azo compounds incorporating an oxindole scaffold in up to 91% yield along with a 93% ee value under the catalysis of (DHQ)2AQN.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China.
authors.forename: Hai-Bin
authors.initials: HB
authors.lastname: Yang
authors.forename: Yun-Zhou
authors.initials: YZ
authors.lastname: Zhao
authors.forename: Rui
authors.initials: R
authors.lastname: Sang
authors.forename: Min
authors.initials: M
authors.lastname: Shi
mesh_terms: D000880:Anthraquinones / Q000737:chemistry*; D001391:Azo Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D004987:Ethers / Q000737:chemistry*; D006835:Hydrazones / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D007510:Isatin / Q000737:chemistry*; D015394:Molecular Structure; D000078183:Oxindoles; D013237:Stereoisomerism
chemical_list: D000880:Anthraquinones; D001391:Azo Compounds; D004987:Ethers; D006835:Hydrazones; D007211:Indoles; D000078183:Oxindoles; C000592673:hydroquinine(anthraquinone-1,4-diyl)diether; C022960:2-oxindole; D007510:Isatin