title: Desensitization protocol should not be used in acute lymphoblastic leukemia patients with silent inactivation of PEGasparaginase.
authors.affiliation: Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam Department of Pediatric Oncology and Hematology, University of Groningen, University Medical Center Groningen, Groningen The Netherlands.
authors.forename: Wing H
authors.initials: WH
authors.lastname: Tong
authors.affiliation: Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam.
authors.forename: Rob
authors.initials: R
authors.lastname: Pieters
authors.affiliation: Department of Pediatric Oncology and Hematology, University of Groningen, University Medical Center Groningen, Groningen The Netherlands.
authors.forename: Wim J E
authors.initials: WJ
authors.lastname: Tissing
authors.affiliation: Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam i.vandersluis@erasmusmc.nl.
authors.forename: Inge M
authors.initials: IM
authors.lastname: van der Sluis
mesh_terms: D000906:Antibodies / Q000276:immunology*; D001215:Asparaginase / Q000008:administration & dosage / Q000276:immunology*; D003888:Desensitization, Immunologic; D006801:Humans; D006967:Hypersensitivity / Q000150:complications / Q000276:immunology* / Q000628:therapy*; D011092:Polyethylene Glycols / Q000008:administration & dosage; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*
chemical_list: D000906:Antibodies; D011092:Polyethylene Glycols; C042705:pegaspargase; D001215:Asparaginase
keywords: PEGasparaginase; acute lymphoblastic leukemia; desensitization protocol; silent inactivation