title: sp(3)C-H bond alkylation of ketones with alkenes via ruthenium(II) catalysed dehydrogenation of alcohols.
abstract: The sp(3)C-H bond functionalisation of 2-pyridyl ethanols upon reaction with alkenes, in the presence of a [RuCl2(arene)]2 catalyst and Cu(OAc)2·H2O, is performed under mild conditions without additional base. This reaction proceeds via a tandem alcohol dehydrogenation/alkylation with alkenes of the resulting ketone at its α sp(3)C-H bond.
authors.affiliation: UMR 6226 CNRS-Université de Rennes 1 "Institut des Sciences Chimiques de Rennes", Team "Organometallics: Materials and Catalysis", Centre for Catalysis and Green Chemistry, Campus de Beaulieu, 35042 Rennes Cedex, France. christophe.darcel@univ-rennes1.fr pierre.dixneuf@univ-rennes1.fr.
authors.forename: Bin
authors.initials: B
authors.lastname: Li
authors.forename: Christophe
authors.initials: C
authors.lastname: Darcel
authors.forename: Pierre H
authors.initials: PH
authors.lastname: Dixneuf