title: New monoterpenoid alkaloids from the aerial parts of Uncaria hirsuta.
abstract: To investigate the chemical constituents of medicinal plant Uncaria hirsuta, three new monoterpenoid alkaloids, named hirsutanines A-C (1-3), were isolated. Their structures with absolute configurations were elucidated by means of NMR, X-ray diffraction and CD analysis. Compound 3 was the first dimeric monoterpenoid alkaloid obtained from genus Uncaria.
authors.affiliation: a College of Pharmacy, Institute of Traditional Chinese Medicine & Natural Products, Jinan University , Guangzhou 510632 , P.R. China.
authors.forename: Jun-Feng
authors.initials: JF
authors.lastname: Jia
authors.forename: Yuan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Xiao-Jun
authors.initials: XJ
authors.lastname: Huang
authors.forename: Sheng-Yuan
authors.initials: SY
authors.lastname: Zhang
authors.forename: Hai-Yan
authors.initials: HY
authors.lastname: Tian
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
authors.forename: Wen-Cai
authors.initials: WC
authors.lastname: Ye
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D002942:Circular Dichroism; D018360:Crystallography, X-Ray; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D039821:Monoterpenes / Q000737:chemistry / Q000302:isolation & purification*; D019906:Nuclear Magnetic Resonance, Biomolecular; D032070:Uncaria / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D004365:Drugs, Chinese Herbal; D039821:Monoterpenes; C000592942:hirsutanine A; C000592943:hirsutanine B; C000592944:hirsutanine C
keywords: Rubiaceae; Uncaria hirsuta; alkaloids