title: Sensorimotor performance in euthymic bipolar disorder: the MPraxis (PennCNP) analysis.
abstract: BACKGROUND
  Sensorimotor deficits are an important phenomenological facet observed in patients with bipolar disorder (BD). However, there is little research on this topic. We hypothesize that the MPraxis test can be used to screen for motor impairments in BD aiming movements.
  
  
  METHODS
  The MPraxis, which is a quick and easy-to-apply computerized test, measures sensorimotor control. During the test, the participant must move the computer mouse cursor over an ever-shrinking green box and click on it once. We predict that the MPraxis test is capable of detecting differences in sensorimotor performance between patients with BD and controls. We assessed 21 euthymic type I BD patients, without DSM-IV-TR Axis I comorbidity, and 21 healthy controls.
  
  
  CONCLUSIONS
  Compared to the controls, the patients with BD presented a lower response time in their movements in all conditions. Our results showed sensorimotor deficits in BD and suggested that the MPraxis test can be used to screen for motor impairments in patients with euthymic BD.
authors.affiliation: Mental Health Department, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
authors.forename: Maila de C
authors.initials: Mde C
authors.lastname: Neves
authors.affiliation: Physical Education Department, Universidade Federal de Viçosa (UFV), Viçosa, MG, Brazil.
authors.forename: Maicon R
authors.initials: MR
authors.lastname: Albuquerque
authors.affiliation: Mental Health Department, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
authors.forename: Fernando S
authors.initials: FS
authors.lastname: Neves
authors.affiliation: Physical Education Department, UFMG, Belo Horizonte, MG, Brazil.
authors.forename: Guilherme M
authors.initials: GM
authors.lastname: Lage
authors.affiliation: Mental Health Department, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
authors.forename: Leandro
authors.initials: L
authors.lastname: Malloy-Diniz
authors.affiliation: Mental Health Department, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Nicolato
authors.affiliation: Mental Health Department, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
authors.forename: Humberto
authors.initials: H
authors.lastname: Corrêa
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001714:Bipolar Disorder / Q000503:physiopathology*; D016022:Case-Control Studies; D056228:Feedback, Sensory / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011597:Psychomotor Performance / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D012016:Reference Values; D015203:Reproducibility of Results; D018709:Statistics, Nonparametric; D055815:Young Adult