title: Proliferative, reparative, and reactive benign bone lesions that may be confused diagnostically with true osseous neoplasms.
abstract: Diagnostic problems attending intraosseous and parosteal pseudoneoplastic lesions can be radiographic, or histological, or both. Proliferations in this category may contain cellular fibro-osseous or chondro-osseous tissues that are difficult to separate microscopically from those seen in various true neoplasms of the bones. This review considers the clinicopathologic features of fibrous dysplasia, benign fibro-osseous lesions of the jawbones, osteofibrous dysplasia, metaphyseal fibrous defect, giant-cell reparative granuloma, "brown tumor" of hyperparathyroidism, synovial chondrometaplasia, aneurysmal bone cyst, tumefactive chronic osteomyelitis, proliferative Paget disease, and polyvinylpyrrolidone storage disease of bone.
authors.affiliation: Department of Pathology, University of Virginia Health System, Charlottesville, Virginia. Electronic address: mrwick1@usa.net.
authors.forename: Mark R
authors.initials: MR
authors.lastname: Wick
authors.affiliation: Department of Pathology, Our Lady's Hospital for Sick Children, Crumlin, Dublin, Ireland.
authors.forename: Michael B
authors.initials: MB
authors.lastname: McDermott
authors.affiliation: Department of Pathology, University of Washington Medical Center, Seattle, Washington.
authors.forename: Paul E
authors.initials: PE
authors.lastname: Swanson
mesh_terms: D017824:Bone Cysts, Aneurysmal / Q000175:diagnosis / Q000473:pathology*; D001848:Bone Diseases, Developmental / Q000175:diagnosis / Q000473:pathology*; D001851:Bone Diseases, Metabolic / Q000473:pathology; D001859:Bone Neoplasms / Q000175:diagnosis / Q000473:pathology*; D049109:Cell Proliferation; D003937:Diagnosis, Differential; D006801:Humans
keywords: Bone pseudotumors; Fibrous dysplasia; Infections simulating neoplasms; Metabolic bone diseases