title: An off-the-shelf sensing system for physiological phosphates.
abstract: An off-the-shelf supramolecular sensing system was designed to discriminate biologically relevant phosphates in neutral water using multivariate data analysis. The system is based on an indicator displacement assay comprising only two unmodified commercially available components: a dendritic poly-electrolyte and a common fluorescent dye. Effective discrimination of nucleotide diphosphates and inorganic diphosphate was achieved through principal component analysis (PCA).
authors.affiliation: Department of Chemistry, The University of Alabama, Tuscaloosa, Alabama 35487, USA. marco.bonizzoni@ua.edu.
authors.forename: Alie M
authors.initials: AM
authors.lastname: Mallet
authors.forename: Yuanli
authors.initials: Y
authors.lastname: Liu
authors.forename: Marco
authors.initials: M
authors.lastname: Bonizzoni
mesh_terms: D000244:Adenosine Diphosphate / Q000032:analysis*; D003565:Cytidine Diphosphate / Q000032:analysis*; D005456:Fluorescent Dyes; D006153:Guanosine Diphosphate / Q000032:analysis*; D006863:Hydrogen-Ion Concentration; D010710:Phosphates / Q000032:analysis*; D011108:Polymers / Q000737:chemistry; D025341:Principal Component Analysis; D014867:Water / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D010710:Phosphates; D011108:Polymers; D014867:Water; D006153:Guanosine Diphosphate; C002189:polyelectrolyte 60; D000244:Adenosine Diphosphate; D003565:Cytidine Diphosphate