title: 18F-FDG PET as a monitoring tool to assess treatment response in bilateral adrenal histoplasmosis.
abstract: A 60-year-old woman with clinical and biochemical features suggestive of adrenal insufficiency was found to have bilateral adrenal masses on CT scan and was subjected to F-FDG PET scan. The scan showed hypermetabolic mediastinal nodes in addition to intense tracer uptake in bilateral adrenal masses. CT-guided adrenal biopsy grew Histoplasma capsulatum on Sabouraud dextrose agar culture. A second F-FDG PET scan after 6 months of appropriate antifungal therapy showed a significant decrease in intensity of uptake consistent with the clinical outcome.
authors.affiliation: From the *Department of Endocrinology, Seth GS Medical College; †Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Centre Annexe; and ‡Department of Microbiology, Seth GS Medical College, Mumbai, India.
authors.forename: Rajeev
authors.initials: R
authors.lastname: Kasaliwal
authors.forename: Gaurav
authors.initials: G
authors.lastname: Malhotra
authors.forename: Amol
authors.initials: A
authors.lastname: Bukan
authors.forename: Ramesh V
authors.initials: RV
authors.lastname: Asopa
authors.forename: Shashir
authors.initials: S
authors.lastname: Wanjare
authors.forename: Nalini S
authors.initials: NS
authors.lastname: Shah
mesh_terms: D000311:Adrenal Glands / Q000000981:diagnostic imaging* / Q000382:microbiology* / Q000473:pathology; D001706:Biopsy; D005260:Female; D019788:Fluorodeoxyglucose F18; D006660:Histoplasmosis / Q000000981:diagnostic imaging* / Q000382:microbiology*; D006801:Humans; D008875:Middle Aged; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D019788:Fluorodeoxyglucose F18