title: Gas chromatography on wall-coated open-tubular columns with ionic liquid stationary phases.
abstract: Ionic liquids have moved from novel to practical stationary phases for gas chromatography with an increasing portfolio of applications. Ionic liquids complement conventional stationary phases because of a combination of thermophysical and solvation properties that only exist for ionic solvents. Their high thermal stability and low vapor pressure makes them suitable as polar stationary phases for separations requiring high temperatures. Ionic liquids are good solvents and can be used to expand the chemical space for separations. They are the only stationary phases with significant hydrogen-bond acidity in common use; they extend the hydrogen-bond basicity of conventional stationary phases; they are as dipolar/polarizable as the most polar conventional stationary phases; and some ionic liquids are significantly less cohesive than conventional polar stationary phases. Problems in column coating techniques and related low column performance, column activity, and stationary phase reactivity require further exploration as the reasons for these features are poorly understood at present.
authors.affiliation: Room 185 Chemistry, Wayne State University, Detroit, MI 48202, USA. Electronic address: cfp@chem.wayne.edu.
authors.forename: Colin F
authors.initials: CF
authors.lastname: Poole
authors.affiliation: Room 185 Chemistry, Wayne State University, Detroit, MI 48202, USA.
authors.forename: Nicole
authors.initials: N
authors.lastname: Lenca
mesh_terms: D002849:Chromatography, Gas / Q000295:instrumentation* / Q000379:methods; D006358:Hot Temperature; D006860:Hydrogen Bonding; D052578:Ionic Liquids / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry
chemical_list: D052578:Ionic Liquids; D012997:Solvents
keywords: Column characterization; Gas chromatography; Ionic liquids; Solvation parameter model; Stationary phases; Thermophysical properties