title: Is the change of integrin α(v)β(3) expression in the infarcted myocardium related to the clinical outcome?
abstract: Two adult male patients with myocardial infarction underwent Ga-BNOTA-PRGD2 (arginine-glycine-aspartic acid [RGD]) PET/CT scans. The initial images that were acquired within 1 week after the cardiac event showed RGD retention in the infarcted regions in both patients. At follow-up Ga-BNOTA-PRGD2 PET/CT scans, RGD uptake was again noticed in the infracted region in the patient who was still had symptoms. However, in the patient who had become asymptomatic, RGD uptake in the infarcted region was no longer visualized.
authors.affiliation: From the Department of Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, People's Republic of China.
authors.forename: Yaping
authors.initials: Y
authors.lastname: Luo
authors.forename: Yi
authors.initials: Y
authors.lastname: Sun
authors.forename: Zhaohui
authors.initials: Z
authors.lastname: Zhu
authors.forename: Fang
authors.initials: F
authors.lastname: Li
mesh_terms: D000328:Adult; D006801:Humans; D039302:Integrin alphaVbeta3 / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000628:therapy*; D009842:Oligopeptides / Q000378:metabolism; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D039302:Integrin alphaVbeta3; D009842:Oligopeptides; C047981:arginyl-glycyl-aspartic acid