title: Management of chronic rhinosinusitis in asthma patients: is there still a debate?
abstract: The united airway concept in which upper and lower respiratory conditions are present in one patient requires special consideration. There is some evidence linking chronic rhinosinusitis and asthma, but a good understanding of the pathophysiology and combined management is still lacking, a fact that leads to discussion. Bronchial asthma is more prevalent in patients who suffer chronic rhinosinusitis. On the other hand, patients with asthma have a greater prevalence of rhinosinusitis than patients without asthma. The effect of chronic rhinosinusitis in patients with or without nasal polyps on asthma treatment, whether medical or surgical, is controversial. Some studies show worsening, other trials improvement, and others no effect. Direct comparisons between surgical and medical treatments are few. Most of the current literature available about this intriguing combination does not provide a good level of evidence. Thus, randomized clinical trials should be performed to better understand the management when asthma and CRS occur together. This review aims to summarize the current state of this association regarding the effects of different types of treatment.
authors.affiliation: Rhinology Unit and Smell Clinic, Otorhinolaryngology Department, Hospital Clínic i Universitari, Villarroel 170, 08036, Barcelona, Catalonia, Spain.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Lehrer
authors.forename: Joaquim
authors.initials: J
authors.lastname: Mullol
authors.forename: Freddy
authors.initials: F
authors.lastname: Agredo
authors.forename: Isam
authors.initials: I
authors.lastname: Alobid
mesh_terms: D001249:Asthma / Q000150:complications / Q000628:therapy*; D002908:Chronic Disease; D003937:Diagnosis, Differential; D006801:Humans; D009666:Nose / Q000601:surgery; D012220:Rhinitis / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D016896:Treatment Outcome