title: [Progress of studies on mechanisms of acupuncture underlying regulation of cardiac function via autonomic nervous system].
abstract: Acupuncture therapy has been confirmed to be effective in treating cardiovascular diseases in clinical practice. Acupuncture-induced balance of the autonomic nervous system activities is one of its key mechanisms. In the present paper, the authors review progress of studies on acupuncture treatment of cardiovascular diseases from 1) regulating cardiac sympathetic-beta-adrenergic receptor activity and myocardial intracellular GTP-binding protein (Gs)-adenylylcyclase (AC)-cyclic adenosine monophosphate (cAMP)-protein kinase (PKA) signaling, and 2) balancing cardiac sympathetic and vagal nerve activities. Due to limited experimental conditions, in-depth studies about the mechanisms of acupuncture intervention underlying improvement of cardiovascular functions are relatively fewer up to now. Along with the further development of modern biology, the mechanism of acupuncture intervention underlying regulation of cardiac function via autonomic nerve system will be revealed in detail.
authors.forename: Ya-Li
authors.initials: YL
authors.lastname: Wang
authors.forename: Zhi
authors.initials: Z
authors.lastname: Yu
authors.forename: Bin
authors.initials: B
authors.lastname: Xu
mesh_terms: D015670:Acupuncture Therapy; D000818:Animals; D001341:Autonomic Nervous System / Q000502:physiology*; D006321:Heart / Q000294:innervation* / Q000502:physiology*; D006801:Humans