title: Preclinical research: Make mouse studies work.
authors.forename: Steve
authors.initials: S
authors.lastname: Perrin
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000235:genetics / Q000473:pathology / Q000628:therapy; D000818:Animals; D002423:Cause of Death; D002986:Clinical Trials as Topic / Q000191:economics / Q000592:standards; D004195:Disease Models, Animal; D018450:Disease Progression; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical / Q000191:economics / Q000379:methods* / Q000592:standards*; D005189:False Positive Reactions; D017408:Guidelines as Topic; D006207:Half-Life; D006801:Humans; D051379:Mice; D009928:Organ Specificity; D015203:Reproducibility of Results; D012107:Research Design; D013482:Superoxide Dismutase / Q000172:deficiency / Q000235:genetics / Q000378:metabolism; D000072105:Superoxide Dismutase-1; D016019:Survival Analysis; D057170:Translational Research, Biomedical / Q000191:economics / Q000379:methods* / Q000592:standards*; D017211:Treatment Failure
chemical_list: C000606290:SOD1 protein, human; C000606291:Sod1 protein, mouse; D013482:Superoxide Dismutase; D000072105:Superoxide Dismutase-1