title: Why is the neural control of cerebral autoregulation so controversial?
abstract: Cerebral autoregulation refers to the mechanisms that act to keep cerebral blood flow (CBF) constant during changes in blood pressure. The mechanisms of cerebral autoregulation, especially in humans, are poorly understood but are undoubtedly multifactorial and likely reflect many redundant pathways that potentially differ between species. Whether sympathetic nervous activity influences CBF and/or cerebral autoregulation in humans remains controversial. Following a brief introduction to cerebral autoregulation, this review highlights the likely reasons behind the controversy of the neural control of cerebral autoregulation. Finally, suggestions are provided for further studies to improve the understanding of the neural control of CBF regulation.
authors.affiliation: Center for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia - Okanagan Kelowna, British Columbia Canada.
authors.forename: Philip N
authors.initials: PN
authors.lastname: Ainslie
authors.affiliation: Department of Kinesiology, Faculty of Medicine, Université Laval Québec Canada ; Research Center of the Institut Universitaire de Cardiologie et de Pneumologie de Québec Québec Canada.
authors.forename: Patrice
authors.initials: P
authors.lastname: Brassard