title: Haematological alterations induced by oral subacute exposure to fenvalerate, nitrate and their combination in domestic buffalo, Bubalus bubalis.
abstract: The present study investigated haematological alterations induced by oral subacute exposure to fenvalerate, nitrate and their combination in the domestic buffalo, Bubalus bubalis. Fenvalerate exposure produced significant declines in haemoglobin (Hb), total leukocyte count (TLC), total erythrocyte count (TEC) and mean corpuscular haemoglobin concentration (MCHC), and a corresponding elevation in mean corpuscular volume (MCV). Following oral exposure to sodium nitrate, significant declines in blood Hb, TLC, TEC, MCH and MCHC, and a significant elevation in MCV occurred. Combined exposure to fenvalerate and sodium nitrate produced severe effects with an appreciably more prominent decline in Hb, TLC, TEC and MCHC and a significant elevation in MCV. The percentage of methaemoglobin was observed to follow an elevating trend in animals exposed to sodium nitrate alone (0.69 %-13.8 %) and in combination with fenvalerate (0.75 %-13.7 %).
authors.affiliation: Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, 141004, India, kamalg27@yahoo.com.
authors.forename: Kamalpreet Kaur
authors.initials: KK
authors.lastname: Gill
authors.forename: H S
authors.initials: HS
authors.lastname: Sandhu
authors.forename: Rajdeep
authors.initials: R
authors.lastname: Kaur
mesh_terms: D000818:Animals; D002020:Buffaloes / Q000502:physiology*; D004305:Dose-Response Relationship, Drug; D004906:Erythrocyte Count; D006454:Hemoglobins; D007306:Insecticides / Q000633:toxicity*; D007958:Leukocyte Count; D008297:Male; D009566:Nitrates / Q000633:toxicity*; D009570:Nitriles / Q000633:toxicity*; D011722:Pyrethrins / Q000633:toxicity*; D018675:Toxicity Tests
chemical_list: D006454:Hemoglobins; D007306:Insecticides; D009566:Nitrates; D009570:Nitriles; D011722:Pyrethrins; C031618:sodium nitrate; C017690:fenvalerate