title: [Amniotic fluid volume and maternal outcomes in women with preterm premature rupture of membranes].
abstract: OBJECTIVE
  To describe the potential influence of amniotic fluid on the maternal outcome of preterm premature rupture of membranes (PROM).
  
  
  METHODS
  An observational, retrospective cohort study was conducted between December 2012 and January 2008 on 86 pregnant women with preterm PROM and a gestational age (GA) of 24 to 35 weeks. The amniotic fluid index (AFI) was used to measure aminiotic fluid volume. Pregnant women were compared at two cut-off points: those with AFI <5.0 and ≥5.0 cm and AFI <3.0 and ≥3.0 cm. We excluded women with hypertensive disorders, diabetes mellitus, fetal malformations and a diagnosis of infections at admission. For statistical analysis, we used the χ2 test or Fisher's exact test, when appropriate, and simple linear regression analysis, with the level of significance set at 5%. We calculated the Risk Ratio (RR) and its 95% confidence interval (95%CI).
  
  
  RESULTS
  When maternal outcomes were assessed by comparing ILA ≥5.0 versus <5.0 cm, no significant differences were detected. However, when considering ILA <3.0 and ≥3.0 cm, there was an increased risk of chorioamnionitis (36.7 versus10.7%, RR: 3.4, 95%CI 1.4 -8.3, p=0.004), with no significant differences for the other variables. There was also a statistically significant positive correlation between AFI and gestational age at delivery (R2=0.78, p<0.0001).
  
  
  CONCLUSIONS
  AFI <3.0 cm causes a three-fold increase in the risk for chorioamnionitis; also, the higher the ILA, the higher the gestational age at delivery.
authors.affiliation: Programa de Pós-gradução em Cuidados Intensivos, Instituto de Medicina Integral Professor Fernando Figueira, Recife, PE, Brasil.
authors.forename: Adriane Farias
authors.initials: AF
authors.lastname: Patriota
authors.affiliation: Centro de Atenção à Mulher, Instituto de Medicina Integral Professor Fernando Figueira, Recife, PE, Brasil.
authors.forename: Gláucia Virgínia de Queiroz Lins
authors.initials: GV
authors.lastname: Guerra
authors.affiliation: Centro de Atenção à Mulher, Instituto de Medicina Integral Professor Fernando Figueira, Recife, PE, Brasil.
authors.forename: Brena Carvalho Pinto
authors.initials: BC
authors.lastname: de  Melo
authors.affiliation: Residência Médica de Ginecologia e Obstetrícia, Instituto de Medicina Integral Professor Fernando Figueira, Recife, PE, Brasil.
authors.forename: Alessandra Coelho
authors.initials: AC
authors.lastname: Santos
authors.affiliation: Residência Médica de Ginecologia e Obstetrícia, Instituto de Medicina Integral Professor Fernando Figueira, Recife, PE, Brasil.
authors.forename: Alberto Callou
authors.initials: AC
authors.lastname: Torres Júnior
authors.affiliation: Instituto de Medicina Integral Professor Fernando Figueira, Recife, PE, Brasil.
authors.forename: Alex Sandro Rolland
authors.initials: AS
authors.lastname: Souza
mesh_terms: D000653:Amniotic Fluid; D015331:Cohort Studies; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000503:physiopathology*; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies