title: Sensitivity of resonance frequency analysis for detecting early implant failure: a case-control study.
abstract: OBJECTIVE
  The aim of this study was to test the sensitivity of the resonance frequency analysis for detecting early implant failure.
  
  
  METHODS
  In all, 3,786 implants placed from June 2007 to January 2013 were retrospectively evaluated. A total of 20 implants (in 20 patients) placed in pristine bone were found to have failed before loading. The implant stability quotient (ISQ) values were extracted from these 20 implants at baseline (immediate) and 4 months after placement (delayed). Simple linear regression, logistic regression, and two-way contingency tables were used to test for the relationships between ISQ values and early implant failure.
  
  
  RESULTS
  Immediate ISQ values were significantly related to failure (odds ratio [OR] = 4.27). Furthermore, the results of the second regression showed a significant relationship between ISQ at delayed measurement and implant failure (OR = 9.20). For immediate ISQ, it seems that the 73.7% correct classifications were obtained at the cost of an incorrect classification of 55% of the implant failures. However, for the delayed ISQ, 86.2% correct classifications were obtained at the cost of assuming that all implants will survive.
  
  
  CONCLUSIONS
  The present study showed that ISQ values are not reliable in predicting early implant failure. In addition, the real cutoff ISQ value to differentiate between success and early implant failure remains to be determined.
authors.forename: Alberto
authors.initials: A
authors.lastname: Monje
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Ortega-Oller
authors.forename: Pablo
authors.initials: P
authors.lastname: Galindo-Moreno
authors.forename: Andrés
authors.initials: A
authors.lastname: Catena
authors.forename: Florencio
authors.initials: F
authors.lastname: Monje
authors.forename: Francisco
authors.initials: F
authors.lastname: O'Valle
authors.forename: Fernando
authors.initials: F
authors.lastname: Suarez
authors.forename: Hom-Lay
authors.initials: HL
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D003758:Dental Implantation, Endosseous / Q000009:adverse effects*; D019232:Dental Restoration Failure; D019544:Equipment Failure Analysis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016348:Osseointegration / Q000502:physiology; D012189:Retrospective Studies; D014732:Vibration