title: Molecular diversity of acid-catalyzed one-pot reaction of arylamines, methyl propiolate, and isatins.
abstract: Under the catalysis of p-TsOH, ß-enamino esters, generated in situ from the reaction of arylamines and propiolate, were reacted with isatins to afford isatinylidene bis(3-arylamino)acrylates in moderate yields. When BF3·OEt2 was used as catalyst, similar reactions of the in situ generated ß-enamino esters resulted in the corresponding spiro[indoline-3,4'-pyridine] derivatives in good yields.
authors.affiliation: College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou, 225002, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Gao
authors.forename: Jing
authors.initials: J
authors.lastname: Sun
authors.forename: Chao-Guo
authors.initials: CG
authors.lastname: Yan
mesh_terms: D000146:Acids, Carbocyclic / Q000138:chemical synthesis / Q000737:chemistry*; D000588:Amines / Q000138:chemical synthesis / Q000737:chemistry*; D001557:Benzenesulfonates / Q000737:chemistry*; D002384:Catalysis; D007510:Isatin / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000146:Acids, Carbocyclic; D000588:Amines; D001557:Benzenesulfonates; D007510:Isatin; C029501:4-toluenesulfonic acid