title: Predictors of future health-related quality of life in survivors of adolescent cancer.
abstract: The purpose of this study was to identify characteristics associated with health-related quality of life (HRQOL) among long-term survivors of adolescent cancer enrolled in the Childhood Cancer Survivor Study. Thirty percent of survivors reported poor physical and/or mental HRQOL. Race/ethnicity, education, and head/neck disfigurement were significantly associated with poor mental HRQOL, while sex, age, household income, obesity, alkylating agents, pelvic radiation, head/neck or limb disfigurement, and walking with a limp were associated with poor physical HRQOL. Identification of high-risk adolescent cancer patients may facilitate timely intervention to attempt to minimize the impact of cancer and treatment on subsequent quality of life.
authors.affiliation: From the Division of Epidemiology and Biostatistics, University of Memphis, School of Public Health, Memphis, Tennessee.
authors.forename: Vikki G
authors.initials: VG
authors.lastname: Nolan
authors.forename: Kevin R
authors.initials: KR
authors.lastname: Krull
authors.forename: James G
authors.initials: JG
authors.lastname: Gurney
authors.forename: Wendy
authors.initials: W
authors.lastname: Leisenring
authors.forename: Leslie L
authors.initials: LL
authors.lastname: Robison
authors.forename: Kirsten K
authors.initials: KK
authors.lastname: Ness
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000523:psychology*; D011788:Quality of Life; D011795:Surveys and Questionnaires; D017741:Survivors / Q000523:psychology*
keywords: adolescent cancer survivor; quality of life