title: [Nonspecific low-back pain: from symptomatic treatment to pathogenesis-based treatment].
abstract: OBJECTIVE
  To study the efficacy and safety of artrosilene in the combination with piascledine in patients with low-back pain.
  
  
  METHODS
  Sixty patients, 42 women and 18 men (mean age 53,6±10,4 years) with chronic nonspecific low-back pain were treated with artrosilene (ketoprofen lysine salt) in the combination with the chondro protector piascledine (a mix of avocado and soybean oil extracts).
  
  
  RESULTS
  There the persistent decrease in the intensity of pain syndrome and severity of vertebral syndrome and improvement of quality of life.
  
  
  CONCLUSIONS
  The drugs can be recommended for treatment of nonspecific low-back pain.
authors.forename: V V
authors.initials: VV
authors.lastname: Alekseev
authors.forename: A V
authors.initials: AV
authors.lastname: Alekseev
authors.forename: G D
authors.initials: GD
authors.lastname: Gol'dzon
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use*; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007660:Ketoprofen / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D017116:Low Back Pain / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D008239:Lysine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010840:Phytosterols / Q000009:adverse effects / Q000627:therapeutic use*; D010936:Plant Extracts / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome; D014810:Vitamin E / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D004338:Drug Combinations; D010840:Phytosterols; D010936:Plant Extracts; C003884:piascledine; D014810:Vitamin E; C029946:ketoprofen lysine; D007660:Ketoprofen; D008239:Lysine