title: Theranostic nanomedicine for cancer detection and treatment.
abstract: Cancer is the second leading cause of death in the USA according to the American Cancer Society. In the past 5 years, "theranostic nanomedicine", for both therapeutics and imaging, has shown to be "the right drug for the right patient at the right moment" to manage deadly cancers. This review article presents an overview of recent developments, mainly from the authors' laboratories, along with potential medical applications for theranostic nanomedicine including basic concepts and critical properties. Finally, we outline the future research direction and possible challenges for theranostic nanomedicine research.
authors.affiliation: Department of Chemistry and Biochemistry, Jackson State University, 1400 J.R. Lynch St, Jackson, MS, USA.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Fan
authors.affiliation: Division of Biochemical Toxicology, National Center for Toxicological Research, Food and Drug Administration, 3900 NCTR Road, Jefferson, AR, USA.
authors.forename: Peter P
authors.initials: PP
authors.lastname: Fu
authors.affiliation: Department of Chemistry and Biochemistry, Jackson State University, 1400 J.R. Lynch St, Jackson, MS, USA.
authors.forename: Hongtao
authors.initials: H
authors.lastname: Yu
authors.affiliation: Department of Chemistry and Biochemistry, Jackson State University, 1400 J.R. Lynch St, Jackson, MS, USA. Electronic address: paresh.c.ray@jsums.edu.
authors.forename: Paresh C
authors.initials: PC
authors.lastname: Ray
mesh_terms: D000818:Animals; D003131:Combined Modality Therapy; D003952:Diagnostic Imaging / Q000379:methods; D016503:Drug Delivery Systems; D006801:Humans; D058990:Molecular Targeted Therapy; D050997:Nanomedicine / Q000379:methods; D036103:Nanotechnology; D009369:Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D009360:Neoplastic Cells, Circulating
keywords: Circulating tumor cell diagnosis; Combined therapy; Photothermal therapy; Selective cancer treatment; Theranostic nanomedicine