title: Medical management of adult headache.
abstract: We review the therapies for primary headache disorders: migraine, chronic migraine, tension-type headache, and cluster headache. Recommendations follow the evidence-based treatments so far as is possible with expert opinion to give clinical guidance. Headache has 2 levels of care: acute treatments designed to stop a headache from progressing and alleviate all symptoms associated with the headache and preventive therapies for patients whose headache frequency is such that by itself produces significant disability and impact on quality of life, or where the frequency of use of acute medications, regardless of efficacy, poses risks in terms of overuse or adverse events.
authors.affiliation: Department of Neurology, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA. Electronic address: dhcdoc@gmail.com.
authors.forename: Frederick G
authors.initials: FG
authors.lastname: Freitag
authors.affiliation: Department of Neurology, Froedtert Hospital, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
authors.forename: Fallon
authors.initials: F
authors.lastname: Schloemer
mesh_terms: D000700:Analgesics / Q000009:adverse effects / Q000627:therapeutic use; D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects / Q000627:therapeutic use; D019274:Botulinum Toxins, Type A / Q000009:adverse effects / Q000627:therapeutic use; D017326:Clinical Trials, Phase III as Topic; D006261:Headache / Q000188:drug therapy* / Q000517:prevention & control; D006801:Humans; D008881:Migraine Disorders / Q000188:drug therapy* / Q000517:prevention & control; D016032:Randomized Controlled Trials as Topic; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects / Q000627:therapeutic use; D018781:Tension-Type Headache / Q000188:drug therapy / Q000517:prevention & control; D014363:Tryptamines / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D000700:Analgesics; D000929:Antidepressive Agents, Tricyclic; D019274:Botulinum Toxins, Type A; D017367:Selective Serotonin Reuptake Inhibitors; D014363:Tryptamines
keywords: Analgesics; Anti-epileptic drugs; Beta blockers; Natural therapies; Nonsteroidal anti-inflammatory drugs; Triptans; US consortium guideline