title: Effectiveness of desensitizing agents in relieving the pre- and postcementation sensitivity for full coverage restorations: a clinical evaluation.
abstract: Patients frequently report sensitivity of prepared abutment teeth during the temporization period and after the fnal cementation of full coverage restoration. Purpose of this clinical investigation was to evaluate the effectiveness of desensitizing agents in reducing the pre- and postcementation sensitivity for full coverage restorations and to compare the relative effcacy of three in offce applied desensitizing agents in relieving the postcementation sensitivity with the use of glass ionomer luting cement.
  
  
  METHODS
  This study consisted of 30 patients requiring either full coverage restoration or 3 unit fxed partial denture. Total of 40 restorations (n = 40) were made and were randomly assigned into four groups comprising 10 restoration (n = 10) in each group. Group C control where no desensitizer application was done, group BB applied with BisBlock dentin desensitizer (Bisco Inc.), group ST applied with Systemp desensitizer (Ivoclar Vivadent), group GC applied with GC Tooth Mousse desensitizer (GC Asia). Desensitizer application was done immediately after the tooth preparation. Sensitivity of the tested abutment was determined by the patient response to cold, hot and bite stimuli and were recorded on visual analog scale (VAS). Sensitivity level scores was evaluated at 4 time intervals, i.e. 1 week after desensitizer application at baseline precementation appointment and others at 5 minutes, 1 day and 1 week postcementation appointment. VAS score data was statistically analyzed using one-way ANOVA followed by post hoc Tukey's test.
  
  
  RESULTS
  BisBlock and GC Tooth Mousse desensitizer resulted in statistically signifcant (p < 0.01) reduction in postcementation sensitivity of glass ionomer cement in comparison to Systemp desensitizer at 5 minutes, 1 week postcementation time interval with no statistical difference was seen between all desensitizer groups at 1 day postcementation. Application of BisBlock and GC Tooth Mousse desensitizer resulted in highly signifcant (p < 0.01) reduction in sensitivity level at the end of 1 week.
  
  
  CONCLUSIONS
  Desensitizer's application on the prepared abutment teeth is considerably effective in relieving both pre- and postcementation sensitivity for full coverage restoration over the short duration of time. Immediate reduction in postoperative sensitivity relatively in a short time period may be benefcial in terms of patient's comfort. Nonetheless, multicenter long-term clinical trials should be conducted to confrm the results.
  
  
  CONCLUSIONS
  Efficacy of BisBlock and GC Tooth Mousse desensitizer was more in relieving the postcementation sensitivity of glass ionomer cement at various time intervals in comparison to Systemp desensitizer. In conclusion, application of desensitizers was beneficial to reduce the pre- and postcementation abutment sensitivity.
authors.affiliation: Reader, Department of Prosthodontics, Institute of Dental Education and Advanced Studies, Gwalior, Madhya Pradesh, India.
authors.forename: Naveen
authors.initials: N
authors.lastname: Gupta
authors.affiliation: Reader, Department of Conservative Dentistry and Endodontics G Pulla Reddy Dental College and Hospital, Kurnool, Andhra Pradesh India.
authors.forename: Upendra Natha
authors.initials: UN
authors.lastname: Reddy
authors.affiliation: Professor, Department of Oral and Maxillofacial Surgery, Sri Sai Dental College and Research Institute, Srikakulam, Andhra Pradesh India.
authors.forename: P Leela
authors.initials: PL
authors.lastname: Vasundhar
authors.affiliation: Professor, Department of Oral and Maxillofacial Surgery, Lenora Institute of Dental Sciences, Rajanmundry, Andhra Pradesh, India.
authors.forename: K Sita
authors.initials: KS
authors.lastname: Ramarao
authors.affiliation: Reader, Department of Orthodontics, Hi-Tech Dental College Bhubaneswar, Odisha, India.
authors.forename: Kvv Pratap
authors.initials: KP
authors.lastname: Varma
authors.affiliation: Senior Lecturer, Department of Prosthodontics, The Oxford Dental College and Hospital, Bengaluru, Karnataka, India, e-mail: drvinod@mail.com.
authors.forename: V
authors.initials: V
authors.lastname: Vinod
mesh_terms: D002364:Caseins / Q000627:therapeutic use; D002484:Cementation / Q000379:methods*; D003442:Crowns; D000044:Dental Abutments; D003738:Dental Cements / Q000737:chemistry; D003794:Dental Restoration, Temporary; D057133:Dentin Desensitizing Agents / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000145:classification / Q000517:prevention & control; D003830:Denture, Partial, Fixed; D003833:Denture, Partial, Temporary; D004338:Drug Combinations; D005500:Follow-Up Studies; D005899:Glass Ionomer Cements / Q000737:chemistry; D005976:Glutaral / Q000627:therapeutic use; D006801:Humans; D008689:Methacrylates / Q000627:therapeutic use; D019815:Oxalic Acid / Q000627:therapeutic use; D010147:Pain Measurement; D016037:Single-Blind Method; D019231:Tooth Preparation, Prosthodontic / Q000379:methods; D064232:Visual Analog Scale; D015034:Zinc Oxide / Q000737:chemistry
chemical_list: C514542:BisBlock; D002364:Caseins; D003738:Dental Cements; D057133:Dentin Desensitizing Agents; D004338:Drug Combinations; D005899:Glass Ionomer Cements; D008689:Methacrylates; C489334:Systemp.desensitizer; C474196:Tempbond NE; C447032:casein phosphopeptide-amorphous calcium phosphate nanocomplex; D019815:Oxalic Acid; D015034:Zinc Oxide; D005976:Glutaral