title: Recent trends in orthopedic surgery aiming to improve quality of life for those with rheumatoid arthritis: data from a large observational cohort.
abstract: OBJECTIVE
  To describe current trends in the numbers of rheumatoid arthritis (RA)-related surgeries.
  
  
  METHODS
  The number of operations was determined for patients with RA in a large observational cohort [Institute of Rheumatology, Rheumatoid Arthritis (IORRA)] enrolled from 2001 to 2012.
  
  
  RESULTS
  The total number of operations peaked in 2002 and gradually decreased thereafter, but began to increase again in 2008. The number of total knee replacements has decreased since 2003, while the number of wrist and foot arthroplasties and the number of artificial finger prosthesis surgeries have increased gradually.
  
  
  CONCLUSIONS
  Our results suggest that the number of orthopedic surgeries may change in response to changes in the drug therapy for RA.
authors.affiliation: From the Institute of Rheumatology, Tokyo Women's Medical University, Shinjuku, Tokyo, 162-0054, Japan.
authors.forename: Shigeki
authors.initials: S
authors.lastname: Momohara
authors.forename: Eisuke
authors.initials: E
authors.lastname: Inoue
authors.forename: Katsunori
authors.initials: K
authors.lastname: Ikari
authors.forename: Kensuke
authors.initials: K
authors.lastname: Ochi
authors.forename: Osamu
authors.initials: O
authors.lastname: Ishida
authors.forename: Koichiro
authors.initials: K
authors.lastname: Yano
authors.forename: Yu
authors.initials: Y
authors.lastname: Sakuma
authors.forename: Shinji
authors.initials: S
authors.lastname: Yoshida
authors.forename: Takuma
authors.initials: T
authors.lastname: Koyama
authors.forename: Naoko
authors.initials: N
authors.lastname: Koenuma
authors.forename: Atsuo
authors.initials: A
authors.lastname: Taniguchi
authors.forename: Hisashi
authors.initials: H
authors.lastname: Yamanaka
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000601:surgery*; D002867:Chromones / Q000627:therapeutic use; D015331:Cohort Studies; D016208:Databases, Factual / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007564:Japan; D007596:Joints / Q000601:surgery; D008297:Male; D019637:Orthopedic Procedures / Q000706:statistics & numerical data* / Q000639:trends*; D010880:Piperidines / Q000627:therapeutic use; D011743:Pyrimidines / Q000627:therapeutic use; D011758:Pyrroles / Q000627:therapeutic use; D011788:Quality of Life; D013449:Sulfonamides / Q000627:therapeutic use; D016559:Tacrolimus / Q000627:therapeutic use
chemical_list: D018501:Antirheumatic Agents; D002867:Chromones; D010880:Piperidines; D011743:Pyrimidines; D011758:Pyrroles; D013449:Sulfonamides; C519076:iguratimod; C479163:tofacitinib; D016559:Tacrolimus
keywords: BIOLOGICS; DISEASE-MODIFYING ANTIRHEUMATIC DRUGS; ORTHOPEDIC JOINT SURGERY; RHEUMATOID ARTHRITIS