title: Umbilical cord serum lipids between early and late clamping in full-term newborns. A systematic assignment treatment group.
abstract: OBJECTIVE
  The aim of the current study was to determine any relationship between the timing of clamping of the umbilical cord and the lipid levels circulating in umbilical artery and vein.
  
  
  METHODS
  We studied a clinical trial with systematic assignment in 229 single-fetus full-term deliveries with normal gestational course and spontaneous delivery; out of these, 111 were subjected to early clamping (EC, within 10 s of delivery) and 118 to late clamping (LC, at 2 min). In all cases, total cholesterol (TC), triglycerides (TG), and phospholipids were measured in sera from umbilical artery and vein.
  
  
  RESULTS
  TC and TG values were significantly higher in the EC group than in the LC group in both umbilical artery and vein. Comparing values between umbilical artery and vein in the two clamping groups, in the EC group, all studied lipids TC, TG and phospholipids were significantly higher in vein than in artery. In the LC group, only TC was higher in vein.
  
  
  CONCLUSIONS
  Umbilical cord lipid levels are related to the timing of umbilical cord clamping, finding which is noteworthy, because they are essential component of postnatal development. Our study confirms that delivery acts as an important modifier of fetal lipid levels.
authors.affiliation: Department Obstetrics and Gynaecology, School of Medicine, University of Granada , Spain .
authors.forename: Jesús
authors.initials: J
authors.lastname: Florido
authors.forename: Catalina
authors.initials: C
authors.lastname: de Paco-Matallana
authors.forename: M Soledad
authors.initials: MS
authors.lastname: Quezada
authors.forename: M Carmen
authors.initials: MC
authors.lastname: Garrido-Sánchez
authors.forename: Carmen
authors.initials: C
authors.lastname: Padilla
authors.forename: Olga
authors.initials: O
authors.lastname: Ocón
authors.forename: Juan De Dios
authors.initials: Jde D
authors.lastname: Luna
authors.forename: Julio Jose
authors.initials: JJ
authors.lastname: Ochoa-Herrera
mesh_terms: D000328:Adult; D015982:Bias; D002784:Cholesterol / Q000097:blood*; D003250:Constriction; D005260:Female; D005312:Fetal Blood / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D012107:Research Design; D047929:Term Birth / Q000097:blood*; D013997:Time Factors; D014280:Triglycerides / Q000097:blood*; D014470:Umbilical Cord / Q000601:surgery*; D055815:Young Adult
chemical_list: D014280:Triglycerides; D002784:Cholesterol
keywords: Lipids; term newborn; umbilical cord clamping