title: Lung squamous cell carcinoma metastasizing to the nasopharynx following bronchoscopy intervention therapies: a case report.
abstract: Metastatic carcinoma to the nasopharynx is extremely rare, and few cases have been reported in the literature. In the present report, we describe the case of a patient with a mass in the nasopharynx found by bronchoscopy. Our patient was a 61-year-old man receiving multiple bronchoscopy intervention therapies for advanced lung squamous cell carcinoma (SCC), which was histopathologically confirmed. The SCC metastasized to the nasopharynx following the bronchoscopy intervention therapies. The lesion was considered metastatic from lung cancer on the basis of clinical and histological clues. The exact mechanism of lung cancer metastasis to the nasopharynx in this case remains unclear because either implantation or hematogenous and lymphatic spread is possible. A thorough head and neck examination should be undertaken during bronchoscopic evaluation, especially in patients receiving bronchoscopy intervention therapies. The early detection of a silent nasopharyngeal metastasis is important to choosing from among the multiple treatment options available.
authors.forename: Jian-bin
authors.initials: JB
authors.lastname: Hu
authors.forename: Mei
authors.initials: M
authors.lastname: Jin
authors.forename: En-guo
authors.initials: EG
authors.lastname: Chen
authors.affiliation: Department of Radiation Oncology, Sir Run Run Shaw Hospital of Zhejiang University Medical School, No, 3 Qingchun East Road, 310016 Hangzhou, Zhejiang Province, China. sunxiaonan@hotmail.com.
authors.forename: Xiao-nan
authors.initials: XN
authors.lastname: Sun
mesh_terms: D001999:Bronchoscopy / Q000009:adverse effects*; D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology* / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000209:etiology / Q000556:secondary*; D011379:Prognosis