title: Sphenoid wing meningioma behavior on 11C-PiB and 18F-FDG PET.
abstract: Two patients with mild cognitive impairment underwent C-PiB and F-FDG brain PET. Both patients had previously gone through a contrast-enhanced MRI scan that revealed extra-axial tumors next to the sphenoid wing, suggestive of meningiomas. C-PiB PET images showed a highly increased uptake by the extra-axial masses. These 2 cases represent 1.2% of our C-PiB population (n = 163). No meningioma was found with negative C-PiB uptake. The F-FDG concentration was not increased within the lesions. C-PiB could be used as a meningioma marker.
authors.affiliation: From the Institute for Neurological Research Dr Raúl Carrea, Foundation Against Neurological Disease in Childhood (FLENI), Buenos Aires, Argentina.
authors.forename: Hernan
authors.initials: H
authors.lastname: Chaves
authors.forename: Yanina
authors.initials: Y
authors.lastname: Bergamo
authors.forename: Santiago
authors.initials: S
authors.lastname: Paz
authors.forename: Flavio
authors.initials: F
authors.lastname: Sanchez
authors.forename: Silvia
authors.initials: S
authors.lastname: Vazquez
mesh_terms: D000368:Aged; D000814:Aniline Compounds; D052160:Benzothiazoles; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging*; D008579:Meningioma / Q000000981:diagnostic imaging*; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D013844:Thiazoles; D014057:Tomography, X-Ray Computed
chemical_list: C475519:2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole; D000814:Aniline Compounds; D052160:Benzothiazoles; D019275:Radiopharmaceuticals; D013844:Thiazoles; D019788:Fluorodeoxyglucose F18