title: Parkinson's disease: recent advances.
abstract: While a curative treatment for Parkinson's disease remains elusive, our understanding of disease mechanisms as well as preclinical and pre-motor early manifestations has improved greatly over the past years. An agent with proven disease modifying properties has not yet been identified but symptomatic treatment options for affected patients have improved. For patients with motor complications, this includes invasive approaches such as deep brain stimulation and continuous device-aided drug delivery. The many facets of non-motor problems patients are faced with have finally been fully recognized and have become the target of treatment trials, as have been non-pharmacological approaches.
authors.affiliation: Department of Neurology, Karl Landsteiner Institute for Neuroimmunological and Neurodegenerative Disorders, Donauspital/Danube Hospital, Vienna, Austria, regina.katzenschlager@chello.at.
authors.forename: Regina
authors.initials: R
authors.lastname: Katzenschlager
mesh_terms: D015331:Cohort Studies; D046690:Deep Brain Stimulation / Q000639:trends; D018491:Dopamine Agonists / Q000008:administration & dosage; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010300:Parkinson Disease / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy*; D012189:Retrospective Studies
chemical_list: D018491:Dopamine Agonists