title: Efficacy of ofatumumab against rituximab-resistant B-CLL/SLL cells with low CD20 protein expression.
authors.affiliation: Department of Haematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Shimada
authors.forename: Akihiro
authors.initials: A
authors.lastname: Tomita
authors.forename: Shigeki
authors.initials: S
authors.lastname: Saito
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Kiyoi
mesh_terms: D000368:Aged; D000911:Antibodies, Monoclonal / Q000494:pharmacology / Q000627:therapeutic use*; D061067:Antibodies, Monoclonal, Humanized; D058846:Antibodies, Monoclonal, Murine-Derived / Q000494:pharmacology / Q000627:therapeutic use*; D018951:Antigens, CD20 / Q000378:metabolism*; D019008:Drug Resistance, Neoplasm / Q000235:genetics; D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000175:diagnosis / Q000188:drug therapy* / Q000378:metabolism*; D000069283:Rituximab; D016896:Treatment Outcome
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D058846:Antibodies, Monoclonal, Murine-Derived; D018951:Antigens, CD20; D000069283:Rituximab; C527517:ofatumumab
keywords: CD20; chronic lymphocytic leukaemia; drug resistance; ofatumumab; rituximab