title: Plant systems biology: insights, advances and challenges.
abstract: Plants dwelling at the base of biological food chain are of fundamental significance in providing solutions to some of the most daunting ecological and environmental problems faced by our planet. The reductionist views of molecular biology provide only a partial understanding to the phenotypic knowledge of plants. Systems biology offers a comprehensive view of plant systems, by employing a holistic approach integrating the molecular data at various hierarchical levels. In this review, we discuss the basics of systems biology including the various 'omics' approaches and their integration, the modeling aspects and the tools needed for the plant systems research. A particular emphasis is given to the recent analytical advances, updated published examples of plant systems biology studies and the future trends.
authors.affiliation: Department of Biosciences, Centre for Advanced Studies in Plant Biotechnology and Genetic Engineering, Saurashtra University, Rajkot, 360005, Gujarat, India, bhavisha.sheth@gmail.com.
authors.forename: Bhavisha P
authors.initials: BP
authors.lastname: Sheth
authors.forename: Vrinda S
authors.initials: VS
authors.lastname: Thaker
mesh_terms: D000465:Algorithms; D019175:DNA Methylation; D055106:Genome-Wide Association Study; D023281:Genomics; D055432:Metabolomics; D008962:Models, Theoretical; D010944:Plants / Q000235:genetics* / Q000378:metabolism; D012984:Software; D049490:Systems Biology