title: Toxic megacolon after abdominoplasty: a case report.
abstract: After an accepted technique of abdominoplasty, a 66-year-old woman developed Clostridium difficile-associated diarrhea, leading to toxic megacolon and subsequent subtotal colectomy. The presumed etiology is chronic use of a proton pump inhibitor. This was addressed in a 2012 "white paper" warning issued by the Food and Drug Administration. This article presents the course of this case as well as a review of the pertinent literature.
authors.affiliation: From the Plastic Surgery in the Department of Surgery, LSU Health Sciences Center, New Orleans, LA.
authors.forename: James W
authors.initials: JW
authors.lastname: Wade
mesh_terms: D061645:Abdominoplasty; D000368:Aged; D003082:Colectomy; D004761:Enterocolitis, Pseudomembranous / Q000139:chemically induced* / Q000150:complications*; D064098:Esomeprazole / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D008532:Megacolon, Toxic / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D009336:Necrosis; D054328:Proton Pump Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D054328:Proton Pump Inhibitors; D064098:Esomeprazole