title: Relationship between lower urinary tract symptoms and metabolic syndrome in a Chinese male population.
abstract: OBJECTIVE
  To investigate whether the metabolic syndrome (MetS) is a risk factor for lower urinary tract symptoms (LUTS), as defined by the International Prostate Symptom Score in a Chinese male population with benign prostate hyperplasia (BPH).
  
  
  METHODS
  We retrospectively analyzed the clinical data obtained from 1,052 Chinese men with BPH. Serum levels of prostate specific antigen, fasting blood glucose (FBG), high-density lipoprotein cholesterol, total cholesterol and triglyceride were determined and recorded. Multiple logistic regression statistical analysis was used to investigate the degree of the association between LUTS and MetS.
  
  
  RESULTS
  Of the 1,052 enrolled patients, 648 (61.60 %) had moderate LUTS and 404 (38.40 %) had severe LUTS. A multiple logistic regression analysis showed that age (OR 2.02, 95 % CI 1.04-4.63), FBG (OR 3.65, 95 % CI 1.68-7.98) and presence of MetS (OR 3.64, 95 % CI 1.24-6.14) were significant predictors of severe LUTS.
  
  
  CONCLUSIONS
  The results of our study suggest that MetS is associated with an increase risk of total volume and annual growth rate of prostate.
authors.affiliation: The Second Affiliated Hospital of Guangzhou Medical University, Changgang Dong Lu, No. 250, Guangzhou, 510260, China, thatdaypjg@163.com.
authors.forename: J G
authors.initials: JG
authors.lastname: Pan
authors.forename: M
authors.initials: M
authors.lastname: Liu
authors.forename: X
authors.initials: X
authors.lastname: Zhou
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000032:analysis; D002681:China; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D005215:Fasting; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D008875:Middle Aged; D011467:Prostate / Q000473:pathology; D017430:Prostate-Specific Antigen / Q000097:blood; D011470:Prostatic Hyperplasia / Q000097:blood / Q000150:complications / Q000473:pathology; D012189:Retrospective Studies; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D008076:Cholesterol, HDL; D014280:Triglycerides; D002784:Cholesterol; D017430:Prostate-Specific Antigen