title: Carbon-dot-based two-photon visible nanocarriers for safe and highly efficient delivery of siRNA and DNA.
abstract: A simple and versatile nanoparticulate siRNA and DNA delivery vehicle is reported, based on photonic Cdots by using Alkyl-PEI2k for surface passivation.
authors.affiliation: State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics &Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
authors.forename: Liqin
authors.initials: L
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics &Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
authors.forename: Xiaoyong
authors.initials: X
authors.lastname: Wang
authors.affiliation: Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Ashwinkumar
authors.initials: A
authors.lastname: Bhirde
authors.affiliation: State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics &Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
authors.forename: Jianbo
authors.initials: J
authors.lastname: Cao
authors.affiliation: State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics &Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Zeng
authors.affiliation: Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Xinglu
authors.initials: X
authors.lastname: Huang
authors.affiliation: Department of Chemistry and Laboratory for Emerging Materials and Technology, Clemson University, Clemson, South Carolina 29634, USA.
authors.forename: Yaping
authors.initials: Y
authors.lastname: Sun
authors.affiliation: State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics &Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Liu
authors.affiliation: Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Xiaoyuan
authors.initials: X
authors.lastname: Chen
mesh_terms: D000818:Animals; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D004247:DNA / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D037742:Nanotubes, Carbon / Q000737:chemistry; D017785:Photons; D011094:Polyethyleneimine / Q000737:chemistry; D045663:Quantum Dots / Q000737:chemistry*; D034741:RNA, Small Interfering / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D014162:Transfection; D014184:Transplantation, Homologous
chemical_list: D037742:Nanotubes, Carbon; D034741:RNA, Small Interfering; D011094:Polyethyleneimine; D004247:DNA
keywords: RNA interference; carbon dots; gene delivery; plasmid DNA; polyethylenimine