title: A ratiometric fluorescent probe for the detection of hydroxyl radicals in living cells.
abstract: A naphthalimide-naphthyridine derivative has been synthesized for the detection of hydroxyl radicals. It can distinguish hydroxyl radicals from other reactive oxygen species with high selectivity and short response time. Moreover, it has no cellular toxicity, and can be effectively used for intracellular detection of hydroxyl radicals.
authors.affiliation: Department of Chemistry & Innovation Center of Chemistry for Energy Materials, Fudan University, 220 Handan Road, Shanghai 200433, P. R. China. yitao@fudan.edu.cn.
authors.forename: Luyan
authors.initials: L
authors.lastname: Meng
authors.forename: Yongquan
authors.initials: Y
authors.lastname: Wu
authors.forename: Tao
authors.initials: T
authors.lastname: Yi
mesh_terms: D000818:Animals; D002460:Cell Line; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D017665:Hydroxyl Radical / Q000032:analysis* / Q000378:metabolism; D008264:Macrophages / Q000737:chemistry* / Q000378:metabolism; D051379:Mice; D017382:Reactive Oxygen Species / Q000032:analysis / Q000378:metabolism
chemical_list: D005456:Fluorescent Dyes; D017382:Reactive Oxygen Species; D017665:Hydroxyl Radical