title: Examination of the ovarian reserve after generation of unilateral rudimentary uterine horns in rats.
abstract: OBJECTIVE
  The purpose of this experimental rat model study is to evaluate the changes in the ovarian environment after excision of the rudimentary horn.
  
  
  METHODS
  Ten female Wistar albino rats were used in this study. One cm of right uterine horn length was excised in the first operation. Two months after the first operation, all animals were sacrificed to obtain ovaries for histological examination. Mann-Whitney U test and Student's t-test were used for statistical analysis purposes. Statistical significance was defined as P < 0.005.
  
  
  RESULTS
  The number of primordial follicles (P = 0.415), primary follicles (P = 0.959), preantral follicles (P = 0.645), antral follicles (P = 0.328), and Graafian follicles (P = 0.721) was decreased and the number of atretic follicles (P = 0.374) increased in the right ovarian side. Howeve,r this difference was not found to be statistically significant.
  
  
  CONCLUSIONS
  The results of this experimental rat model study suggest that the excision of rudimentary horn could have negative effects on ipsilateral ovarian functions.
authors.affiliation: Department of Obstetrics and Gynecology, Adana Numune Education and Research Hospital, 01330 Adana, Turkey.
authors.forename: Hasan
authors.initials: H
authors.lastname: Toyganözü
authors.affiliation: Department of Obstetrics and Gynecology, Adana Numune Education and Research Hospital, 01330 Adana, Turkey.
authors.forename: Hakan
authors.initials: H
authors.lastname: Nazik
authors.affiliation: Department of Obstetrics and Gynecology, Adana Numune Education and Research Hospital, 01330 Adana, Turkey.
authors.forename: Raziye
authors.initials: R
authors.lastname: Narin
authors.affiliation: Department of Obstetrics and Gynecology, Adana Numune Education and Research Hospital, 01330 Adana, Turkey.
authors.forename: Deniz
authors.initials: D
authors.lastname: Satar
authors.affiliation: Department of Obstetrics and Gynecology, Adana Numune Education and Research Hospital, 01330 Adana, Turkey.
authors.forename: Mehmet Ali
authors.initials: MA
authors.lastname: Narin
authors.affiliation: Department of Pharmacology, Çukurova University Medical School, Adana, Turkey.
authors.forename: Sinem
authors.initials: S
authors.lastname: Büyüknacar
authors.affiliation: Department of Obstetrics and Gynecology, Zeynep Kamil Education and Research Hospital, Istanbul, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Api
authors.affiliation: Department of Obstetrics and Gynecology, Mersin University Medical School, Mersin, Turkey.
authors.forename: Hakan
authors.initials: H
authors.lastname: Aytan
mesh_terms: D000818:Animals; D005260:Female; D006080:Ovarian Follicle / Q000166:cytology; D010053:Ovary / Q000166:cytology / Q000502:physiology* / Q000601:surgery; D051381:Rats; D014599:Uterus / Q000002:abnormalities* / Q000601:surgery*