title: Finite element modeling of the viscoelastic responses of the eye during microvolumetric changes.
abstract: A linear viscoelastic finite element model was built to investigate factors that influenced the intraocular pressure (IOP) elevations due to micro-volumetric changes in the eye at three different rates. The viscoelastic properties of the cornea and the sclera, including the instantaneous modulus, equilibrium modulus, and relaxation time constants, parametrically varied to examine their effects on IOP elevations at different rates of volumetric changes. The simulated responses were in good agreement with the previously reported experimental results obtained from porcine globes, showing the general trend of higher IOP elevations at faster rates. The simulations showed that all viscoelastic properties influenced the profile of the dynamic IOP due to volumetric changes, and the relative significance of a specific parameter was highly dependent on the rate of change.
authors.affiliation: Department of Biomedical Engineering, The Ohio State University, Columbus, USA.
authors.forename: Benjamin Cruz
authors.initials: BC
authors.lastname: Perez
authors.affiliation: Department of Biomedical Engineering, The Ohio State University, Columbus, USA.
authors.forename: Hugh J
authors.initials: HJ
authors.lastname: Morris
authors.affiliation: Department of Biomedical Engineering, The Ohio State University, Columbus, USA.
authors.forename: Richard T
authors.initials: RT
authors.lastname: Hart
authors.affiliation: Department of Biomedical Engineering, The Ohio State University, Columbus, USA ; Department of Ophthalmology, The Ohio State University, Columbus, USA.
authors.forename: Jun
authors.initials: J
authors.lastname: Liu
keywords: Cornea; Finite Element Modeling; Intraocular Pressure; Sclera; Viscoelasticity