title: Portal hypertensive gastropathy and colopathy.
abstract: Portal hypertensive gastropathy (PHG) and colopathy (PHC) are considered complications of portal hypertension. Both entities are clinically relevant because they may cause insidious blood loss or even acute massive gastrointestinal hemorrhage. Endoscopic evaluation is necessary for the diagnosis of PHG and PHC. The existence of different endoscopic criteria for PHG and PHC makes consensus difficult and results in a broad range of reported prevalence. Therapy targeted at reduction of portal pressure and mucosal blood flow has been used to treat acute bleeding; nonselective β-blockers are the most frequently used agents. Further studies are needed to clarify the natural history, pathogenesis, and treatment of PHG and PHC.
authors.affiliation: Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, 22 S. Greene Street, N3W156, Baltimore, MD 21201, USA.
authors.forename: Nathalie H
authors.initials: NH
authors.lastname: Urrunaga
authors.affiliation: Department of Internal Medicine, Medical University of South Carolina, 96 Jonathan Lucas Street, Suite 803, Charleston, SC 29425, USA. Electronic address: rockey@musc.edu.
authors.forename: Don C
authors.initials: DC
authors.lastname: Rockey
mesh_terms: D000208:Acute Disease; D002908:Chronic Disease; D003108:Colonic Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D016099:Endoscopy, Gastrointestinal; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000628:therapy; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications* / Q000473:pathology / Q000628:therapy; D011322:Primary Prevention; D055502:Secondary Prevention; D013272:Stomach Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy
keywords: Bleeding; Cirrhosis; Hemorrhage; Portal hypertension; Pressure