title: Clinical applications and characteristics of apparent diffusion coefficient maps for the brain of two dogs.
abstract: Diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) mapping are functional magnetic resonance imaging techniques for detecting water diffusion. DWI and the ADC map were performed for intracranial lesions in two dogs. In necrotizing leukoencephalitis, cavitated lesions contained a hypointense center with a hyperintense periphery on DWI, and hyperintense signals on the ADC maps. In metastatic sarcoma, masses including a necrotic region were hypointense with DWI, and hyperintense on the ADC map with hyperintense perilesional edema on DWI and ADC map. Since DWI and ADC data reflect the altered water diffusion, they can provide additional information at the molecular level.
authors.affiliation: College of Veterinary Medicine and the Research Institute for Veterinary Science at Seoul National University, Seoul 151-742, Korea.
authors.forename: Boeun
authors.initials: B
authors.lastname: Kim
authors.forename: Kangjae
authors.initials: K
authors.lastname: Yi
authors.forename: Sunyoung
authors.initials: S
authors.lastname: Jung
authors.forename: Seoyeon
authors.initials: S
authors.lastname: Ji
authors.forename: Mincheol
authors.initials: M
authors.lastname: Choi
authors.forename: Junghee
authors.initials: J
authors.lastname: Yoon
mesh_terms: D000818:Animals; D001921:Brain / Q000473:pathology*; D001932:Brain Neoplasms / Q000473:pathology / Q000662:veterinary*; D038524:Diffusion Magnetic Resonance Imaging / Q000662:veterinary*; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D056784:Leukoencephalopathies / Q000473:pathology / Q000662:veterinary*; D009336:Necrosis / Q000662:veterinary; D059906:Neuroimaging / Q000662:veterinary*; D012509:Sarcoma / Q000473:pathology / Q000662:veterinary*
keywords: apparent diffusion coefficient map; brain; diffusion- weighted imaging; dog; magnetic resonance image