title: Retrospective evaluation of micro-focused ultrasound for lifting and tightening the face and neck.
abstract: BACKGROUND
  Microfocused ultrasound (MFU) is an effective means for tightening and lifting lax facial and neck skin.
  
  
  OBJECTIVE
  To evaluate the safety and efficacy of MFU with visualization (MFU-V) for noninvasive treatment of facial and neck skin laxity 180 days after treatment and determine what lifestyle factors affect treatment outcomes.
  
  
  METHODS
  Healthy women (N = 48) previously treated with MFU-V on the face and upper neck were enrolled. Depending on when MFU-V treatment occurred, subjects completed 90- or 180-day follow-up visits or both. Digital images of each subject were obtained before treatment and at follow-up visits.
  
  
  RESULTS
  Data were obtained at 90 (N = 16) and 180 days (N = 45), and physician Global Aesthetic Improvement Scale (GAIS) scores demonstrated that 81.3% and 77.7% patients achieved improvement, respectively. At 90 and 180 days, subject GAIS scores showed 75% and 77.8% of subjects perceived improvement, respectively. At 180 days, blinded reviewer assessments indicated that 67% of subjects showed improvement in appearance. There was no association between improvement and age, Fitzpatrick skin type, alcohol intake, or major illness. One minor adverse event was reported.
  
  
  CONCLUSIONS
  Although the data obtained at 90 days must be interpreted cautiously because of the smaller number of patients, subjects achieved significant lifting and tightening of facial and neck skin up to 180 days after one MFU treatment.
authors.affiliation: Goldman, Butterwick, Fitzpatrick, Groff and Fabi Dermatology Cosmetic Laser, San Diego, California.
authors.forename: Sabrina G
authors.initials: SG
authors.lastname: Fabi
authors.forename: Mitchel P
authors.initials: MP
authors.lastname: Goldman
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005145:Face; D005260:Female; D006801:Humans; D008019:Life Style; D008875:Middle Aged; D009333:Neck; D017060:Patient Satisfaction; D012189:Retrospective Studies; D015361:Rhytidoplasty / Q000009:adverse effects / Q000379:methods*; D015595:Skin Aging; D014464:Ultrasonic Therapy / Q000009:adverse effects / Q000379:methods*