title: Integrative knowledge management to enhance pharmaceutical R&D.
abstract: Information technologies already have a key role in pharmaceutical research and development (R&D), but achieving substantial advances in their use and effectiveness will depend on overcoming current challenges in sharing, integrating and jointly analysing the range of data generated at different stages of the R&D process.
authors.affiliation: IMIM and Universitat Pompeu Fabra, Dr. Aiguader 88, 08003 Barcelona, Spain.
authors.forename: Maria
authors.initials: M
authors.lastname: Marti-Solano
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, Cambridgeshire CB10 1SD, UK.
authors.forename: Ewan
authors.initials: E
authors.lastname: Birney
authors.affiliation: Institut de Recherches Internationales Servier, 53 rue Carnot, 92284 Suresnes Cedex, France.
authors.forename: Antoine
authors.initials: A
authors.lastname: Bril
authors.affiliation: GlaxoSmithKline, Stockley Park West, Uxbridge, Middlesex UB11 1BT, UK.
authors.forename: Oscar
authors.initials: O
authors.lastname: Della Pasqua
authors.affiliation: Systems Biology Institute, 5-6-9 Shirokanedai, Minato, Tokyo 108-0071, Japan; and the RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa 230-0045, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Kitano
authors.affiliation: Netherlands Bioinformatics Centre, 260 NBIC, 6500 HB Nijmegen, The Netherlands; and the Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
authors.forename: Barend
authors.initials: B
authors.lastname: Mons
authors.affiliation: Swiss Institute of Bioinformatics, Quartier Sorge - Batiment Genopode, 1015 Lausanne, Switzerland.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Xenarios
authors.affiliation: IMIM and Universitat Pompeu Fabra, Dr. Aiguader 88, 08003 Barcelona, Spain.
authors.forename: Ferran
authors.initials: F
authors.lastname: Sanz
mesh_terms: D003299:Cooperative Behavior; D004345:Drug Industry / Q000458:organization & administration*; D006801:Humans; D019451:Information Management; D058436:Knowledge Management; D012106:Research / Q000458:organization & administration*; D013678:Technology, Pharmaceutical