title: New cembranoids from the soft coral Sinularia arborea.
abstract: From the ethyl acetate extract of the soft coral Sinularia arborea, a new cembrane-type diterpenoid, arbolide C (1), along with (+)-sarcophytol T (2), an enantiomer of the known cembrane, sarcophytol T, were isolated. The structures of compounds 1 and 2 were established by spectroscopic methods and 1 was found to display an inhibitory effect on the release of elastase by human neutrophils.
authors.forename: Li-Hsueh
authors.initials: LH
authors.lastname: Wang
authors.forename: Kuan-Hua
authors.initials: KH
authors.lastname: Chen
authors.forename: Chang-Feng
authors.initials: CF
authors.lastname: Dai
authors.forename: Tsong-Long
authors.initials: TL
authors.lastname: Hwang
authors.forename: Wei-Hsien
authors.initials: WH
authors.lastname: Wang
authors.forename: Zhi-Hong
authors.initials: ZH
authors.lastname: Wen
authors.forename: Yang-Chang
authors.initials: YC
authors.lastname: Wu
authors.forename: Ping-Jyun
authors.initials: PJ
authors.lastname: Sung
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D006801:Humans; D019272:Leukocyte Elastase / Q000037:antagonists & inhibitors; D015394:Molecular Structure
chemical_list: D004224:Diterpenes; C588200:arbolide C; D019272:Leukocyte Elastase