title: In-hospital clinical outcomes of elderly patients (≥80 years) undergoing percutaneous coronary intervention.
abstract: BACKGROUND
  The clinical outcomes of elderly patients (≥80 years old) undergoing percutaneous coronary intervention (PCI) has not been well established, despite recent advances in both devices and techniques.
  
  
  RESULTS
  We recruited patients from the SHINANO Registry, a prospective, observational, multicenter, cohort study. From August 2012 to July 2013, a total of 1,923 consecutive patients with 2,250 elective/urgent PCIs (2,105 admissions) (mean age, 71±11 years; ≥80 years, 23%; men, 77%) were enrolled. The primary endpoint was procedural success. The secondary endpoints were in-hospital death and in-hospital major adverse cardiovascular events (MACE). The procedural success rate was significantly lower (83.7% vs. 89.1%, P=0.0001), and the rates of in-hospital mortality and MACE were significantly higher in elderly than in non-elderly patients (3.6% vs. 1.5%, P=0.005; 4.4% vs. 2.3%, P=0.016, respectively). For elective PCI, the rates of procedural success and in-hospital MACE were similar between groups (90.3% vs. 91.3%, P=0.65, 2.3% vs. 1.2%, P=0.2, respectively). On multivariate analysis, being elderly was not an independent predictor of procedural failure (OR, 1.15; CI, 0.81-1.61; P=0.43).
  
  
  CONCLUSIONS
  In elderly patients, PCI is safe and feasible. The presence of comorbidities is a more important factor than age alone.
authors.affiliation: Department of Cardiovascular Medicine, Shinshu University School of Medicine.
authors.forename: Takashi
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authors.lastname: Miura
authors.forename: Yusuke
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authors.lastname: Miyashita
authors.forename: Hirohiko
authors.initials: H
authors.lastname: Motoki
authors.forename: Kentaro
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authors.lastname: Shimada
authors.forename: Masanori
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authors.lastname: Kobayashi
authors.forename: Hiroyuki
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authors.lastname: Nakajima
authors.forename: Hikaru
authors.initials: H
authors.lastname: Kimura
authors.forename: Hiroshi
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authors.lastname: Akanuma
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authors.lastname: Mawatari
authors.forename: Toshio
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authors.lastname: Sato
authors.forename: Shoji
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authors.lastname: Hotta
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Kamiyoshi
authors.forename: Takuya
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authors.lastname: Maruyama
authors.forename: Noboru
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authors.lastname: Watanabe
authors.forename: Takayuki
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authors.lastname: Eisawa
authors.forename: Shinichi
authors.initials: S
authors.lastname: Aso
authors.forename: Shinichiro
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authors.lastname: Uchikawa
authors.forename: Naoto
authors.initials: N
authors.lastname: Hashizume
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Sekimura
authors.forename: Takehiro
authors.initials: T
authors.lastname: Morita
authors.forename: Soichiro
authors.initials: S
authors.lastname: Ebisawa
authors.forename: Atsushi
authors.initials: A
authors.lastname: Izawa
authors.forename: Takeshi
authors.initials: T
authors.lastname: Tomita
authors.forename: Jun
authors.initials: J
authors.lastname: Koyama
authors.forename: Uichi
authors.initials: U
authors.lastname: Ikeda
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003324:Coronary Artery Disease / Q000401:mortality* / Q000601:surgery*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention; D011446:Prospective Studies; D012307:Risk Factors