title: Antimicrobial susceptibility of Streptococcus suis isolated from clinically healthy swine in Brazil.
abstract: Streptococcus suis is an important pathogen in the swine industry. This study is the first to report on the antimicrobial susceptibility of S. suis isolated from clinically healthy pigs in Brazil; the fourth major pork producer in the world. The antimicrobial susceptibility of 260 strains was determined by disc diffusion method. Strains were commonly susceptible to ceftiofur, cephalexin, chloramphenicol, and florfenicol, with more than 80% of the strains being susceptible to these antimicrobials. A high frequency of resistance to some of the antimicrobial agents was demonstrated, with resistance being most common to sulfa-trimethoprim (100%), tetracycline (97.69%), clindamycin (84.61%), norfloxacin (76.92%), and ciprofloxacin (61.15%). A high percentage of multidrug resistant strains (99.61%) were also found. The results of this study indicate that ceftiofur, cephalexin, and florfenicol are the antimicrobials of choice for empirical control of the infections caused by S. suis.
authors.affiliation: Departamento de Higiene Veterinária e Saúde Pública. Universidade Estadual Paulista Júlio de Mesquita Filho, São Paulo, Brazil (Cook Siqueira Soares, Paes, Megid); Faculty of Veterinary Medicine, Université de Montréal, Montreal, Quebec (Gottschalk); and Departamento de Parasitologia. Universidade Estadual Paulista Júlio de Mesquita Filho, São Paulo, Brazil (Martins Ribolla, dos Santos Paduan).
authors.forename: Taíssa Cook Siqueira
authors.initials: TC
authors.lastname: Soares
authors.affiliation: Departamento de Higiene Veterinária e Saúde Pública. Universidade Estadual Paulista Júlio de Mesquita Filho, São Paulo, Brazil (Cook Siqueira Soares, Paes, Megid); Faculty of Veterinary Medicine, Université de Montréal, Montreal, Quebec (Gottschalk); and Departamento de Parasitologia. Universidade Estadual Paulista Júlio de Mesquita Filho, São Paulo, Brazil (Martins Ribolla, dos Santos Paduan).
authors.forename: Antonio Carlos
authors.initials: AC
authors.lastname: Paes
authors.affiliation: Departamento de Higiene Veterinária e Saúde Pública. Universidade Estadual Paulista Júlio de Mesquita Filho, São Paulo, Brazil (Cook Siqueira Soares, Paes, Megid); Faculty of Veterinary Medicine, Université de Montréal, Montreal, Quebec (Gottschalk); and Departamento de Parasitologia. Universidade Estadual Paulista Júlio de Mesquita Filho, São Paulo, Brazil (Martins Ribolla, dos Santos Paduan).
authors.forename: Jane
authors.initials: J
authors.lastname: Megid
authors.affiliation: Departamento de Higiene Veterinária e Saúde Pública. Universidade Estadual Paulista Júlio de Mesquita Filho, São Paulo, Brazil (Cook Siqueira Soares, Paes, Megid); Faculty of Veterinary Medicine, Université de Montréal, Montreal, Quebec (Gottschalk); and Departamento de Parasitologia. Universidade Estadual Paulista Júlio de Mesquita Filho, São Paulo, Brazil (Martins Ribolla, dos Santos Paduan).
authors.forename: Paulo Eduardo Martins
authors.initials: PE
authors.lastname: Ribolla
authors.affiliation: Departamento de Higiene Veterinária e Saúde Pública. Universidade Estadual Paulista Júlio de Mesquita Filho, São Paulo, Brazil (Cook Siqueira Soares, Paes, Megid); Faculty of Veterinary Medicine, Université de Montréal, Montreal, Quebec (Gottschalk); and Departamento de Parasitologia. Universidade Estadual Paulista Júlio de Mesquita Filho, São Paulo, Brazil (Martins Ribolla, dos Santos Paduan).
authors.forename: Karina dos Santos
authors.initials: Kdos S
authors.lastname: Paduan
authors.affiliation: Departamento de Higiene Veterinária e Saúde Pública. Universidade Estadual Paulista Júlio de Mesquita Filho, São Paulo, Brazil (Cook Siqueira Soares, Paes, Megid); Faculty of Veterinary Medicine, Université de Montréal, Montreal, Quebec (Gottschalk); and Departamento de Parasitologia. Universidade Estadual Paulista Júlio de Mesquita Filho, São Paulo, Brazil (Martins Ribolla, dos Santos Paduan).
authors.forename: Marcelo
authors.initials: M
authors.lastname: Gottschalk
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000494:pharmacology*; D001938:Brazil; D004352:Drug Resistance, Microbial; D008826:Microbial Sensitivity Tests / Q000662:veterinary; D013290:Streptococcal Infections / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D017011:Streptococcus suis / Q000254:growth & development*; D013552:Swine / Q000382:microbiology*
chemical_list: D000890:Anti-Infective Agents