title: Filamentous supramolecular peptide-drug conjugates as highly efficient drug delivery vehicles.
abstract: We report here a facile approach to prepare filamentous supramolecular peptide-drug conjugates with precise drug/carrier stoichiometry, nearly 100% loading efficiency and exceptional anti-cancer drug efficacy for chemotherapy.
authors.affiliation: Department of Chemistry and Biomolecular Sciences, Clarkson University, Potsdam, NY 13699, USA. hdong@clarkson.edu.
authors.forename: Miao
authors.initials: M
authors.lastname: Yang
authors.forename: Dawei
authors.initials: D
authors.lastname: Xu
authors.forename: Linhai
authors.initials: L
authors.lastname: Jiang
authors.forename: Lin
authors.initials: L
authors.lastname: Zhang
authors.forename: Derek
authors.initials: D
authors.lastname: Dustin
authors.forename: Reidar
authors.initials: R
authors.lastname: Lund
authors.forename: Ling
authors.initials: L
authors.lastname: Liu
authors.forename: He
authors.initials: H
authors.lastname: Dong
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000737:chemistry*; D004337:Drug Carriers / Q000008:administration & dosage / Q000737:chemistry*; D016503:Drug Delivery Systems / Q000379:methods; D056945:Hep G2 Cells; D006801:Humans; D046911:Macromolecular Substances / Q000008:administration & dosage / Q000737:chemistry*; D010455:Peptides / Q000008:administration & dosage / Q000737:chemistry*; D004364:Pharmaceutical Preparations / Q000008:administration & dosage / Q000737:chemistry; D017433:Protein Structure, Secondary
chemical_list: D000970:Antineoplastic Agents; D004337:Drug Carriers; D046911:Macromolecular Substances; D010455:Peptides; D004364:Pharmaceutical Preparations