title: Age and molecular subtypes: impact on surgical decisions.
abstract: Both young patient age and breast cancer molecular subtype impact local recurrence rates and long-term prognosis for women with breast cancer. Although rates of local recurrence are consistently higher in young women and those with high-risk molecular subtypes, this risk does not appear to be overcome by more extensive surgery.
authors.affiliation: Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
authors.forename: Melissa
authors.initials: M
authors.lastname: Pilewskie
authors.forename: Tari A
authors.initials: TA
authors.lastname: King
mesh_terms: D000367:Age Factors; D001943:Breast Neoplasms / Q000145:classification / Q000378:metabolism / Q000473:pathology* / Q000601:surgery*; D003657:Decision Making; D005260:Female; D006801:Humans; D011379:Prognosis; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000378:metabolism*; D011960:Receptors, Estrogen / Q000378:metabolism*; D011980:Receptors, Progesterone / Q000378:metabolism*
chemical_list: D018719:Erb-b2 Receptor Tyrosine Kinases; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone
keywords: age; biologic subtype; breast cancer; local recurrence; surgery