title: Paraneoplastic cerebellar degeneration as the first evidence of malignancy: a case report.
abstract: Paraneoplastic cerebellar degeneration (PCD) is an immune-mediated paraneoplastic disorder affecting the cerebellum. PCD associated with ovarian malignancy is a rare occurrence with fewer than 100 cases reported in published work. PCD patients express anti-Yo antibody, one of the anti-onconeuronal antibodies which is most likely associated with gynecologic or breast malignancies. In this report, we present the case of a 65-year-old postmenopausal woman presenting with acute symptoms of PCD as a first sign of ovarian malignancy.
authors.affiliation: Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: V Aruna
authors.initials: VA
authors.lastname: Kumari
authors.forename: Prerna
authors.initials: P
authors.lastname: Gupta
authors.forename: M V Padma
authors.initials: MV
authors.lastname: Srivastava
authors.forename: Lalit
authors.initials: L
authors.lastname: Kumar
authors.forename: Alka
authors.initials: A
authors.lastname: Kriplani
authors.forename: Neerja
authors.initials: N
authors.lastname: Bhatla
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000150:complications*; D020362:Paraneoplastic Cerebellar Degeneration / Q000209:etiology* / Q000628:therapy
keywords: anti-Yo antibody; carcinoma ovary; paraneoplastic cerebellar degeneration