title: Haploidentical stem cell transplantation in DOCK8 deficiency - Successful control of pre-existing severe viremia with a TCRaß/CD19-depleted graft and antiviral treatment.
authors.affiliation: Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Duesseldorf, Germany. Electronic address: sujal.ghosh@med.uni-duesseldorf.de.
authors.forename: Sujal
authors.initials: S
authors.lastname: Ghosh
authors.affiliation: Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Duesseldorf, Germany.
authors.forename: Friedhelm R
authors.initials: FR
authors.lastname: Schuster
authors.affiliation: Institute of Virology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Duesseldorf, Germany.
authors.forename: Ortwin
authors.initials: O
authors.lastname: Adams
authors.affiliation: Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Duesseldorf, Germany.
authors.forename: Florian
authors.initials: F
authors.lastname: Babor
authors.affiliation: Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Duesseldorf, Germany.
authors.forename: Arndt
authors.initials: A
authors.lastname: Borkhardt
authors.affiliation: Pediatric Hematology/Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
authors.forename: Patrizia
authors.initials: P
authors.lastname: Comoli
authors.affiliation: Children's University Hospital, University of Tuebingen, Tuebingen, Germany.
authors.forename: Rupert
authors.initials: R
authors.lastname: Handgretinger
authors.affiliation: Children's University Hospital, University of Tuebingen, Tuebingen, Germany.
authors.forename: Peter
authors.initials: P
authors.lastname: Lang
authors.affiliation: Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Duesseldorf, Germany.
authors.forename: Hans-Jürgen
authors.initials: HJ
authors.lastname: Laws
authors.affiliation: Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Duesseldorf, Germany.
authors.forename: Meinolf
authors.initials: M
authors.lastname: Siepermann
authors.affiliation: Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Duesseldorf, Germany.
authors.forename: Roland
authors.initials: R
authors.lastname: Meisel
mesh_terms: D000293:Adolescent; D018941:Antigens, CD19 / Q000276:immunology; D000998:Antiviral Agents / Q000627:therapeutic use*; D001739:BK Virus; D005260:Female; D020662:Guanine Nucleotide Exchange Factors / Q000235:genetics; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods*; D006801:Humans; D007074:Immunoglobulin G / Q000627:therapeutic use; D007589:Job Syndrome / Q000150:complications / Q000235:genetics / Q000601:surgery*; D008212:Lymphocyte Depletion; D027601:Polyomavirus Infections / Q000150:complications / Q000188:drug therapy*; D016693:Receptors, Antigen, T-Cell, alpha-beta / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology; D014412:Tumor Virus Infections / Q000150:complications / Q000188:drug therapy*; D014421:Turkey; D014766:Viremia / Q000150:complications / Q000188:drug therapy*
chemical_list: D018941:Antigens, CD19; D000998:Antiviral Agents; C516591:DOCK8 protein, human; D020662:Guanine Nucleotide Exchange Factors; D007074:Immunoglobulin G; D016693:Receptors, Antigen, T-Cell, alpha-beta
keywords: DOCK8 deficiency; HSCT; Hyper IgE; Primary immunodeficiency