title: [Donations after cardiac death kidney transplantation in northwest China].
abstract: OBJECTIVE
  To explore the effect of donations after cardiac death (DCD) kidney transplant performed in northwest China and the measures for management of delayed graft function (DGF).
  
  
  METHODS
  In the period of 2011-2013, a total of 51 families of DCD donor gave their consent to organ donation by signing the informed consent with the help by a Red Cross Organization (ROC) coordinator, and 102 kidneys were retrieved by organ procurement organization (OPO) teams. Ninety-four operations of renal transplantation were carried out in our hospital. All the patients were followed-up and based on the occurrence of DGF after transplantation, they were divided into DGF group and non-DGF group for comparative studies.
  
  
  RESULTS
  The success rate of donation after cardiac death was 29.3%, and the incidence of post-transplantation DGF was 27.7%. The 1-year human/kidney survival rate was 98.9%/95.7%. Within six months after the transplant, the values of eGFR in DGF group were significantly lower and serum creatinine significantly higher than those in non-DGF group (P<0.05), but no significant differences were found between the two groups thereafter (P>0.05). The occurrence of DGF in LifePort mechanical perfusion cohorts was significantly lower than that in the simple cold preservation group (21.5% vs. 41.4%, P<0.05).
  
  
  CONCLUSIONS
  The overall effect of DCD kidney transplant is good despite a high incidence of early DGF, and we recommend the use of low-temperature mechanical perfusion for storage and transportation of DCD donor kidney.
authors.affiliation: Nephropathy Center, the First Affiliated Hospital, Medical College of Xi'an Jiaotong University, Xi'an 710061, shannxi, China. E-mail: drpanxiaoming@126.com.
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Pan
authors.forename: Wujun
authors.initials: W
authors.lastname: Xue
authors.forename: Linjuan
authors.initials: L
authors.lastname: Liu
authors.forename: Heli
authors.initials: H
authors.lastname: Xiang
authors.forename: Chenguang
authors.initials: C
authors.lastname: Ding
authors.forename: Shuqin
authors.initials: S
authors.lastname: He
authors.forename: Li
authors.initials: L
authors.lastname: Ren
authors.forename: Puxun
authors.initials: P
authors.lastname: Tian
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Ding
mesh_terms: D000328:Adult; D002681:China; D003643:Death; D051799:Delayed Graft Function / Q000209:etiology; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D009927:Tissue and Organ Procurement / Q000706:statistics & numerical data*; D055815:Young Adult