title: Adjustable internal structure for reconstructing gradient index profile of crystalline lens.
abstract: Employing advanced technologies in studying the crystalline lens of the eye has improved our understanding of the refractive index gradient of the lens. Reconstructing and studying such a complex structure requires models with adaptable internal geometry that can be altered to simulate geometrical and optical changes of the lens with aging. In this Letter, we introduce an optically well-defined, geometrical structure for modeling the gradient refractive index profile of the crystalline lens with the advantage of an adjustable internal structure that is not available with existing models. The refractive index profile assigned to this rotationally symmetric geometry is calculated numerically, yet it is shown that this does not limit the model. The study provides a basis for developing lens models with sophisticated external and internal structures without the need for analytical solutions to calculate refractive index profiles.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Bahrami
authors.forename: Alexander V
authors.initials: AV
authors.lastname: Goncharov
authors.forename: Barbara K
authors.initials: BK
authors.lastname: Pierscionek
mesh_terms: D003315:Cornea / Q000033:anatomy & histology / Q000502:physiology; D007908:Lens, Crystalline / Q000033:anatomy & histology* / Q000502:physiology*; D008954:Models, Biological; D012029:Refraction, Ocular