title: Why do T cells cause so much trouble?
abstract: In this issue of Blood, Price et al document a 20-year experience with autoimmune lymphoproliferative syndrome (ALPS) patients and healthy mutation-positive relatives, showing that defective lymphocyte apoptosis is associated with an increased incidence of lymphomas.
authors.affiliation: BAYLOR COLLEGE OF MEDICINE.
authors.forename: Kenneth L
authors.initials: KL
authors.lastname: McClain
mesh_terms: D056735:Autoimmune Lymphoproliferative Syndrome / Q000235:genetics* / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D009154:Mutation; D019014:fas Receptor / Q000235:genetics*
chemical_list: C491901:FAS protein, human; D019014:fas Receptor