title: A new lignan glycoside from Chamaecyparis obtusa var. breviramea f. crippsii.
abstract: A new lignan glycoside, (-)-(8S, 8'R)-thujastandin-4-O-beta-D-glucopyranoside (1), together with fourteen known lignanoids (2-15) and one coumarin (16) were isolated from the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii. Their structures were elucidated by extensive spectroscopic and spectrometric analysis. Compound 16 exhibited cytotoxicity against A549, BGC-823 and Hela cell lines with IC50 values of 25.9, 20.9 and 18.5 microM, respectively.
authors.forename: Jian
authors.initials: J
authors.lastname: Xu
authors.forename: Guang-Zhi
authors.initials: GZ
authors.lastname: Zeng
authors.forename: Ke-Li
authors.initials: KL
authors.lastname: Chen
authors.forename: Yi-Mei
authors.initials: YM
authors.lastname: Liu
authors.forename: Zhang-Hua
authors.initials: ZH
authors.lastname: Sun
authors.forename: Ning-Hua
authors.initials: NH
authors.lastname: Tan
authors.forename: Yu-Mei
authors.initials: YM
authors.lastname: Zhang
mesh_terms: D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D029780:Chamaecyparis / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy
chemical_list: D006027:Glycosides; D017705:Lignans