title: Arylphosphonylation and arylazidation of activated alkenes.
abstract: Two radical-mediated processes of activated alkenes, namely arylphosphonylation and arylazidation, are described. The difunctionalization of alkenes by a tandem process that involves radical addition, 1,4-aryl migration, and desulfonylation generates α-aryl-β-heterofunctionalized amides bearing a quaternary stereocenter when the substituent on the nitrogen atom is an aryl group. Alternatively, heterooxindoles or spirobicycles can be obtained with excellent regioselectivity in the presence of an alkyl substituent on the nitrogen atom.
authors.affiliation: Department of Chemistry, Universität Zürich (Switzerland).
authors.forename: Wangqing
authors.initials: W
authors.lastname: Kong
authors.forename: Estíbaliz
authors.initials: E
authors.lastname: Merino
authors.forename: Cristina
authors.initials: C
authors.lastname: Nevado
keywords: alkenes; aryl migration; desulfonylation; difunctionalization; radicals