title: Metabolic syndrome in migraine headache: A case-control study.
abstract: BACKGROUND
  The correlation of metabolic syndrome and migraine headache was evaluated in some previous studies. However there is no study that compared the prevalence of metabolic syndrome in the patients with and without migraine. Control of coincidental factors such as metabolic syndrome reduces therapeutic resistance in migrainous patients. The aim of this study was to compare prevalence of metabolic syndrome in patients with and without migraine headache.
  
  
  METHODS
  200 migrainous patients diagnosed according to International Headache Society and 200 healthy controls without migraine enrolled in this study. Metabolic syndrome was diagnosed according to ATP III criteria in these two groups and compared with each other.
  
  
  RESULTS
  In this study, 17% (34) of migrainous patients and 15% (30) of healthy control without migraine had metabolic syndrome. (P = 0.585). Of the metabolic syndrome components, body mass index (P = 0.05) and waist circumference in migrainous (P = 0.03) were significantly more frequent.
  
  
  CONCLUSIONS
  Our results demonstrate that metabolic syndrome and migraine headache had not significant correlation; however, higher body mass index and waist circumference as metabolic syndrome components had correlated with migraine headache.
authors.affiliation: Isfahan Neurosciences Research Center, Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Mehrzad
authors.initials: M
authors.lastname: Salmasi
authors.affiliation: Isfahan Neurosciences Research Center, Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Laya
authors.initials: L
authors.lastname: Amini
authors.affiliation: Physiology Research Center, Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Shaghayegh Haghjooy
authors.initials: SH
authors.lastname: Javanmard
authors.affiliation: Isfahan Neurosciences Research Center, Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Saadatnia
keywords: Metabolic syndrome; insulin resistance; migraine