title: Surgical treatment of infantile achalasia: a case report and literature review.
abstract: Allgrove syndrome is a rare genetic disorder typically manifested by alacrima, achalasia, and adrenal insufficiency, and is one of the rare causes of achalasia in infants. While the gold standard for achalasia treatment in adults is an esophageal myotomy with fundoplication, a standard treatment for infantile achalasia remains undetermined due to the low number of reported cases and rarity of the disease in this age group. We report a 7.7 kg infant with achalasia secondary to Allgrove syndrome who was successfully treated by Heller myotomy and simultaneous Toupet fundoplication. This case represents one of the smallest patients to ever be treated for achalasia and highlights the role that primary surgical therapy may have for the infantile variant of the disease.
authors.affiliation: Division of Pediatric Surgery, Michael E DeBakey Department of Surgery, Baylor College of Medicine, 6701 Fannin Street Suite 1210, Houston, TX, 77030, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Li
authors.forename: S C
authors.initials: SC
authors.lastname: Fallon
authors.forename: M A
authors.initials: MA
authors.lastname: Helmrath
authors.forename: M
authors.initials: M
authors.lastname: Gilger
authors.forename: M L
authors.initials: ML
authors.lastname: Brandt
mesh_terms: D000309:Adrenal Insufficiency / Q000000981:diagnostic imaging / Q000601:surgery*; D004931:Esophageal Achalasia / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D018662:Fundoplication; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010535:Laparoscopy; D011859:Radiography