title: [Prevalence of metabolic complications after 10 years of antiretroviral treatment in Senegal].
abstract: Among the patients of the cohort still followed after a median of 9 years of antiretroviral treatment (ART), 37% had lipodystrophy, 28% had hypertension and 14% presented with diabetes. This study confirms the association between stavudine and lipodystrophy particulary lipoatrophy and shows that a longer duration of ART was associated with the presence of diabetes. These results highlight the need to implement programs for prevention of cardiovascular risk factors in HIV patients from resource-constrained settings.
authors.affiliation: Centre régional de recherche et de formation à la prise en charge clinique de Fann (CRCF), CHU de Fann, Dakar, Sénégal, dradiouf@yahoo.fr.
authors.forename: A
authors.initials: A
authors.lastname: Diouf
authors.forename: A
authors.initials: A
authors.lastname: Cournil
mesh_terms: D019380:Anti-HIV Agents / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D002318:Cardiovascular Diseases / Q000139:chemically induced / Q000453:epidemiology; D003920:Diabetes Mellitus / Q000139:chemically induced / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000150:complications / Q000453:epidemiology*; D039682:HIV-Associated Lipodystrophy Syndrome / Q000139:chemically induced; D006801:Humans; D008060:Lipodystrophy / Q000139:chemically induced; D008297:Male; D008659:Metabolic Diseases / Q000139:chemically induced* / Q000453:epidemiology*; D008875:Middle Aged; D012675:Senegal / Q000453:epidemiology; D018119:Stavudine / Q000627:therapeutic use
chemical_list: D019380:Anti-HIV Agents; D018119:Stavudine