title: An 11-year-old boy with Plasmodium falciparum malaria and dengue co-infection.
abstract: Malaria and dengue fever are major mosquito-borne public health problems in tropical countries. The authors report a malaria and dengue co-infection in an 11-year-old boy who presented with sustained fever for 10 days. The physical examination revealed a flushed face, injected conjunctivae and left submandibular lymphadenopathy. His peripheral blood smear showed few ring-form trophozoites of Plasmodium falciparum. His blood tests were positive for dengue NS-1 antigen and IgM antibody, and negative for IgG antibody. After the initiation of antimalarial treatment with artesunate and mefloquine, his clinical condition gradually improved. However, he still had low-grade fever that persisted for 6 days. Finally, he recovered well without fluid leakage, shock or severe bleeding. This case report emphasises that early recognition and concomitant treatment of malaria and dengue co-infection in endemic areas can improve clinical outcome and prevent serious complications.
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Chiang Mai, Thailand.
authors.forename: Satja
authors.initials: S
authors.lastname: Issaranggoon na ayuthaya
authors.forename: Anchalee
authors.initials: A
authors.lastname: Wangjirapan
authors.forename: Peninnah
authors.initials: P
authors.lastname: Oberdorfer
mesh_terms: D002648:Child; D060085:Coinfection / Q000175:diagnosis* / Q000469:parasitology / Q000821:virology; D003715:Dengue / Q000175:diagnosis*; D006801:Humans; D016778:Malaria, Falciparum / Q000175:diagnosis*; D008297:Male