The treatment outcome of radical radiotherapy in laryngeal cancer.
OBJECTIVE
This study reports the treatment outcome of radiotherapy alone for laryngeal cancer


METHODS
A retrospective analysis was performed on 138 patients with stage I to IV squamous cell carcinoma of larynx who received radiotherapy alone in Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University, Thailand between 2003 and 2009.


RESULTS
The 4-year local control (LC) rate in all patients was 44.1%. The 4-year overall survival (OS) was 82.1%. The 4-year LC rates for stage I, II, III, and IV were 75.3%, 69.4%, 57.1%, and 36.9%,respectively (p = 0.0055). Finally, the 4-year OS rates for stage I, II, III, and IV were 85%, 78.6%, 91.1%, and 71.5%, respectively. The laryngeal preservation rate of all stages was 73%.


CONCLUSIONS
In conclusion, the treatment outcome of radiotherapy alone in all stages of laryngeal cancer in our center was unsatisfactory when compared to other series.
Imjai
I
Chitapanarux
Ekkasit
E
Tharavichitkul
Somvilai
S
Chakrabandhu
Pitchayaponne
P
Klunklin
Wimrak
W
Onchan
Nantaka
N
Pukanhapan
Jirawattana
J
Srikawin
Pichit
P
Sittitrai
Roy
R
Vongtama
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D059351:Organ Sparing Treatments; D012189:Retrospective Studies