In vitro fertilization-embryo transfer pregnancy was a risk factor for hemorrhagic shock in women with placental polyp.
OBJECTIVE
The aim of this study was to determine the risk factors for hemorrhagic shock in women with placental polyp.


METHODS
Twelve women (group A) developed hemorrhagic shock (shock index<1.5) and received uterine artery embolization (UAE). The other 25 women (group B) had shock index<1.5 and did not receive UAE. All women underwent transcervical resection (TCR). The risk factors for the development of hemorrhagic shock, including the age, conception mode, numbers of previous abortion, gestational weeks at termination of pregnancy (TOP), blood loss weights at TOP and at TCR, were analyzed.


RESULTS
When compared with group B, group A had higher in vitro fertilization-embryo transfer (IVF-ET) pregnancy rate (58.3 versus 12.0%, p<0.01), number of previous abortion (median 1.58 versus 0.68, p<0.05), gestational weeks at TOP (median 36.5 versus 17.0 weeks, p<0.05), and blood loss weight at TOP (median 2151 versus 40 g, p<0.05). A logistic regression analysis reveled that IVF-ET (OR 41, 95% CI 1.3-1264) and blood loss weight at TOP (1.0025, 1.0006-1.0044) were independent risk factors for hemorrhagic shock.


CONCLUSIONS
For the first time, IVF-ET pregnancy was found to be a risk factor for the development of hemorrhagic shock in women with placental polyp.
Department of Obstetrics and Gynecology, Kobe University , Kobe , Japan.
Yoshiya
Y
Miyahara
Natsuko
N
Makihara
Yui
Y
Yamasaki
Yasuhiko
Y
Ebina
Masashi
M
Deguchi
Hideto
H
Yamada
D000028:Abortion, Induced / Q000009:adverse effects; D000328:Adult; D004624:Embryo Transfer / Q000009:adverse effects; D005260:Female; D005307:Fertilization in Vitro / Q000009:adverse effects; D006801:Humans; D016015:Logistic Models; D010920:Placenta / Q000473:pathology / Q000503:physiopathology*; D011127:Polyps / Q000473:pathology / Q000503:physiopathology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology; D012307:Risk Factors; D012771:Shock, Hemorrhagic / Q000209:etiology* / Q000628:therapy; D055357:Uterine Artery Embolization / Q000379:methods*
Assisted reproductive technology; placenta; pregnancy