De novo cerebral arteriovenous malformations: is epileptic seizure a potential trigger?
METHODS
The pathogenesis of cerebral arteriovenous malformations (cAVMs) is still not well understood. Generally, cAVMs are thought to be congenital lesions originating prenatally. We report a 7-year-old boy diagnosed with a de novo cAVM after 3 years of recurrent epileptic seizures.


RESULTS
MR imaging at 4 years of age was normal. Follow-up MR imaging 3 years later demonstrated a de novo 2-cm cAVM in the right occipital lobe, confirmed by conventional angiography. We reviewed five previously reported cases of de novo cAVMs who did not have a previous neurovascular abnormality. Including our case, recurrent epileptic seizures are the major presentation (83.3 %) before de novo cAVM occurrence.


CONCLUSIONS
We suggest that epileptic seizure is a potential trigger of de novo cAVMs.
Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Dongcheng district, 100050, Beijing, China.
Jun
J
Wu
Yu
Y
Li
Yong
Y
Cao
Shuo
S
Wang
D002533:Cerebral Angiography; D002648:Child; D004827:Epilepsy / Q000150:complications*; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000209:etiology*; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D012640:Seizures / Q000150:complications*