Complexation of chlorpropham with hydroxypropyl-β-cyclodextrin and its application in potato sprout inhibition.
The effect of hydroxypropyl-β-cyclodextrin (HPβCD) on the improvement of chlorpropham (CIPC) as a potato sprout inhibitor was investigated. The formation of complex was confirmed by FT-IR spectra, thermoanalysis, (1)H NMR and ROESY. The stoichiometry and stability constant were determined by Job's plot and phase solubility studies, respectively. The inclusion complex CIPC·HPβCD has exhibited different properties from CIPC. The obtained inclusion complex was found to significantly improve the water solubility, thermal stability and dissolution rate of CIPC. In addition, the complex displayed a better effect on sprout inhibition.
Institute of Agricultural Products Storage and Processing, Gansu Academy of Agricultural Sciences, Lanzhou 730070, PR China.
Zheng
Z
Huang
Institute of Agricultural Products Storage and Processing, Gansu Academy of Agricultural Sciences, Lanzhou 730070, PR China.
Shilong
S
Tian
Institute of Agricultural Products Storage and Processing, Gansu Academy of Agricultural Sciences, Lanzhou 730070, PR China. Electronic address: loveyy511@126.com.
Xia
X
Ge
Institute of Agricultural Products Storage and Processing, Gansu Academy of Agricultural Sciences, Lanzhou 730070, PR China.
Jun
J
Zhang
Institute of Agricultural Products Storage and Processing, Gansu Academy of Agricultural Sciences, Lanzhou 730070, PR China.
Shouqiang
S
Li
Institute of Agricultural Products Storage and Processing, Gansu Academy of Agricultural Sciences, Lanzhou 730070, PR China.
Mei
M
Li
Institute of Agricultural Products Storage and Processing, Gansu Academy of Agricultural Sciences, Lanzhou 730070, PR China.
Jianxin
J
Cheng
Tangshan City Urban Construction Management Office of Outer Ring, Tangshan 063000, PR China.
Huaiwen
H
Zheng
D000073738:2-Hydroxypropyl-beta-cyclodextrin; D002748:Chlorpropham / Q000737:chemistry*; D061353:Food Storage; D011198:Solanum tuberosum / Q000187:drug effects* / Q000254:growth & development*; D012995:Solubility; D014867:Water / Q000737:chemistry; D047392:beta-Cyclodextrins / Q000737:chemistry* / Q000494:pharmacology*
D047392:beta-Cyclodextrins; D014867:Water; D002748:Chlorpropham; D000073738:2-Hydroxypropyl-beta-cyclodextrin
Chlorpropham; Hydroxypropyl-β-cyclodextrin; Inclusion complex; Potato sprout inhibition; Solubility