Gross pathology and endocrinology of ovarian cysts in bitches.
A total of 73 bitches with ovarian cysts were ovariohysterectomized. Cysts were characterized by gross pathology and endocrine parameters. Therefore, oestradiol-17ß and progesterone concentrations were assessed in cyst-fluid and corresponding blood plasma in each bitch. Our data demonstrated that multiple cysts were often present in a single individual (82%) and that cysts were commonly found on both ovaries (77%). The number of cysts per individual varied from 1 to 35. Most cysts were small in size (range 0.2-4.0 cm in diameter). No cyst was found to produce solely oestradiol-17ß or progesterone. Plasma levels of oestradiol-17ß and progesterone for a given individual were positively correlated with levels of these same hormones in their cyst-fluid (r = 0.334 and p = 0.001 for oestradiol-17ß; r = 0.419 and p < 0.001 for progesterone). Our study is the first to provide a comprehensive evaluation of the gross pathology and endocrinology of ovarian cysts in a larger number of bitches.
Clinic for Obstetrics, Gynaecology and Andrology of Large and Small Animals with Veterinary Ambulance, Justus-Liebig-University, Giessen, Germany; Pathology Unit, German Primate Center, Leibniz-Institute for Primate Research, Goettingen, Germany.
Y
Y
Knauf
H
H
Bostedt
K
K
Failing
S
S
Knauf
A
A
Wehrend
D000818:Animals; D004283:Dog Diseases / Q000378:metabolism* / Q000473:pathology*; D004285:Dogs; D004958:Estradiol / Q000032:analysis / Q000097:blood; D005260:Female; D010048:Ovarian Cysts / Q000378:metabolism / Q000473:pathology / Q000662:veterinary*; D011374:Progesterone / Q000032:analysis / Q000097:blood
D011374:Progesterone; D004958:Estradiol