Mandibular cortical indices on cone-beam computed tomography images in osteoporotic women on treatment with oral bisphosphonates.
OBJECTIVE
To evaluate the mandibular cortical indices in osteoporotic women receiving oral bisphosphonates (oBPs).


METHODS
The study group included 46 Caucasian women aged over 55 years on treatment with oBPs for postmenopausal osteoporosis. Information recorded included age, weight, height, type of oBP, duration of treatment, comorbid conditions and coadjuvant medication. Forty-six age-matched Caucasian women with no known diagnosis of osteoporosis were selected as the control group. All participants underwent cone-beam computed tomography, and the mandibular cortical width (MCW) and the height from the inferior mandibular border to the mental foramen (MBMF) were measured.


RESULTS
The MBMF was similar in the participants with osteoporosis and in controls. MCW was significantly greater in the participants with osteoporosis than in the controls (p < 0.001).


CONCLUSIONS
Mandibular cortical width should not be used to predict the risk of bisphosphonate-associated osteonecrosis of the jaws.
Dental Medico-Surgical Research Group (OMEQUI), School of Medicine and Dentistry, Santiago de Compostela University, Santiago de Compostela, Spain.
Márcio
M
Diniz-Freitas
Dental Medico-Surgical Research Group (OMEQUI), School of Medicine and Dentistry, Santiago de Compostela University, Santiago de Compostela, Spain.
Paula
P
Fernández-Montenegro
Dental Medico-Surgical Research Group (OMEQUI), School of Medicine and Dentistry, Santiago de Compostela University, Santiago de Compostela, Spain.
Javier
J
Fernández-Feijoo
Dental Medico-Surgical Research Group (OMEQUI), School of Medicine and Dentistry, Santiago de Compostela University, Santiago de Compostela, Spain.
Jacobo
J
Limeres-Posse
Dental Medico-Surgical Research Group (OMEQUI), School of Medicine and Dentistry, Santiago de Compostela University, Santiago de Compostela, Spain.
Antonio
A
González-Mosquera
Primary Care Buccodental Health Unit, Marín Health Centre, Galician Health Service (SERGAS), Pontevedra, Spain.
Emma
E
Vázquez-García
Dental Medico-Surgical Research Group (OMEQUI), School of Medicine and Dentistry, Santiago de Compostela University, Santiago de Compostela, Spain.
Pedro
P
Diz-Dios
D000284:Administration, Oral; D059266:Bisphosphonate-Associated Osteonecrosis of the Jaw / Q000000981:diagnostic imaging / Q000473:pathology; D054893:Cone-Beam Computed Tomography; D004164:Diphosphonates / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008334:Mandible / Q000000981:diagnostic imaging* / Q000473:pathology*; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology*
D004164:Diphosphonates
cone-beam computed tomography; mandibular cortical indices; oral bisphosphonates; osteoporosis