How cyclobutanes are assembled in nature--insights from quantum chemistry.
Biosynthetic production of cyclobutanes leads to many complex natural products. Recently, theoretical work employing quantum chemical calculations has shed light on many of the details of cyclobutane-formation, in particular, for terpene natural products. Specific insights and general principles derived from these theoretical studies are described herein.
Department of Chemistry, University of California-Davis, Davis, CA 95616, USA. djtantillo@ucdavis.edu.
Young J
YJ
Hong
Dean J
DJ
Tantillo
D001688:Biological Products; D003503:Cyclobutanes / Q000737:chemistry* / Q000378:metabolism*; D008956:Models, Chemical; D055601:Organic Chemistry Phenomena; D055668:Photochemical Processes; D013729:Terpenes / Q000737:chemistry / Q000378:metabolism
D001688:Biological Products; D003503:Cyclobutanes; D013729:Terpenes