Adherent cells avoid polarization gradients on periodically poled LiTaO3 ferroelectrics.
The response of fibroblast cells to periodically poled LiTaO3 ferroelectric crystals has been studied. While fibroblast cells do not show morphological differences on the two polarization directions, they show a tendency to avoid the field gradients that occur between polarization domains of the ferroelectric. The response to the field gradients is fully established after one hour, a time at which fibroblasts form their first focal contacts. If suspension cells, with a lower tendency to establish strong surface contacts are used, no influence of the field gradients is observed.
Applied Physical Chemistry, Ruprecht-Karls-University Heidelberg, Im Neuenheimer Feld 253, Heidelberg, 69120, Germany, christof.christophis@pci.uni-heidelberg.de.
Christof
C
Christophis
Elisabetta Ada
EA
Cavalcanti-Adam
Maximilian
M
Hanke
Kenji
K
Kitamura
Alexei
A
Gruverman
Michael
M
Grunze
Peter A
PA
Dowben
Axel
A
Rosenhahn
D000818:Animals; D002448:Cell Adhesion / Q000187:drug effects; D002460:Cell Line; D016764:Cell Polarity / Q000187:drug effects; D005347:Fibroblasts / Q000166:cytology* / Q000187:drug effects*; D008094:Lithium / Q000494:pharmacology*; D010087:Oxides / Q000494:pharmacology*; D051381:Rats; D013635:Tantalum / Q000494:pharmacology*
D010087:Oxides; C473347:lithium tantalate oxide; D013635:Tantalum; D008094:Lithium