Engineering microbial electrocatalysis for chemical and fuel production.
In many biotechnological areas, metabolic engineering and synthetic biology have become core technologies for biocatalyst development. Microbial electrocatalysis for biochemical and fuel production is still in its infancy and reactions rates and the product spectrum are currently very low. Therefore, molecular engineering strategies will be crucial for the advancement and realization of many new bioproduction routes using electroactive microorganisms. The complex and unresolved biochemistry and physiology of extracellular electron transfer and the lack of molecular tools for these new non-model hosts for genetic engineering constitute the major challenges for this effort. This review is providing an insight into the current status, challenges and promising approaches of pathway engineering for microbial electrocatalysis.
Institute of Applied Microbiology-Microbial Electrocatalysis, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany. Electronic address: miriam.rosenbaum@rwth-aachen.de.
Miriam A
MA
Rosenbaum
Institute of Applied Microbiology-Microbial Electrocatalysis, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.
Alexander W
AW
Henrich
D055162:Biocatalysis; D056804:Biofuels; D001709:Biotechnology; D004579:Electron Transport; D005818:Genetic Engineering; D053858:Metabolic Networks and Pathways
D056804:Biofuels