Direct growth of Pt@Ag nanochains on tailorable graphene oxide with a green, in situ, template-free method and its biosensing application.
In this work, we have investigated the in situ growth of Ag nanochains (AgNCs) on carboxyl-functionalized graphene oxide based on enzymatic metalization for the first time. The merit of this method is that the AgNCs could be generated directly on carboxyl-functionalized graphene oxide in a natural, environmentally friendly and sustainable way with high productivity. Furthermore, the Pt nanoparticles were wrapped around the AgNCs (Pt@AgNCs) which manifested some superior functions, such as excellent electrical conductivity and well-defined electrochemical redox activity. With Pt@AgNCs as the electrochemical redox probe, we developed a label-free electrochemical aptasensor for highly sensitive detection of platelet-derived growth factor. A linear response was obtained over a wide range from 6 pM to 40 nM with a detection limit of 1.97 pM.
Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China. yuanruo@swu.edu.cn.
Ying
Y
Zhuo
Yan
Y
Wang
Ruo
R
Yuan
Yaqin
Y
Chai
Yali
Y
Yuan
Lijuan
L
Bai
Ling
L
Zhang
D000077214:Becaplermin; D015374:Biosensing Techniques; D006046:Gold / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D049329:Nanostructures; D010087:Oxides / Q000737:chemistry; D010984:Platinum / Q000737:chemistry*; D020574:Proto-Oncogene Proteins c-sis / Q000737:chemistry; D015203:Reproducibility of Results
D010087:Oxides; D020574:Proto-Oncogene Proteins c-sis; D000077214:Becaplermin; D010984:Platinum; D006046:Gold; D006108:Graphite