A propensity-score matched comparison of perioperative and early renal functional outcomes of robotic versus open partial nephrectomy.
OBJECTIVE
To compare the perioperative and early renal functional outcomes of RPN with OPN for kidney tumors.


METHODS
A total of 209 RPN or OPN patients with availability of preoperative cross-sectional imaging since 2009 at our center were included. To adjust for potential baseline confounders propensity-score matching was performed, which resulted in 94 OPNs matched to 51 RPNs. Perioperative and early renal functional outcomes were compared.


RESULTS
In propensity-score matched analysis, RPN procedures were well tolerated and resulted in significant decreases in postoperative analgesic time (24 vs. 48 hr, p<0.001) and visual analog pain scale (3 vs. 4, p<0.001). Besides, the RPN patients had a significantly shorter LOS (9 vs. 11 days, p = 0.008) and less EBL (100 vs. 200 ml, p<0.001), but median operative time was significantly longer (229 vs. 182 min, p<0.001). Ischemia time, transfusion rates, complication rates, percentage eGFR decline and CKD upstaging were equivalent after RPN versus OPN. In multivariable logistic regression analysis, RPN patients were less likely to have a prolonged LOS (odds ratio [OR]: 0.409; p = 0.016), while more likely to experience a longer operative time (OR: 4.296; p = 0.001). However, the statistical significance for the protective effect of RPN versus OPN in EBL was not confirmed by examining the risk of EBL≥400 ml (OR: 0.488; p = 0.212).


CONCLUSIONS
When adjusted for potential selection biases, RPN offers comparable perioperative and early renal functional outcomes to those of OPN, with the added advantage of improved postoperative pain control and a shorter LOS.
Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Zhenjie
Z
Wu
Department of Radiology, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Mingmin
M
Li
Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Le
L
Qu
Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Huamao
H
Ye
Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Bing
B
Liu
Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Qing
Q
Yang
Department of Radiology, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Jing
J
Sheng
Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Liang
L
Xiao
Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Chen
C
Lv
Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Bo
B
Yang
Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Xu
X
Gao
Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Xiaofeng
X
Gao
Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Chuanliang
C
Xu
Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Jianguo
J
Hou
Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Yinghao
Y
Sun
Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Linhui
L
Wang
D000328:Adult; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007677:Kidney Function Tests; D007680:Kidney Neoplasms / Q000503:physiopathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D059035:Perioperative Period; D057216:Propensity Score; D012044:Regression Analysis; D065287:Robotic Surgical Procedures; D013997:Time Factors; D016896:Treatment Outcome