Improvement in specific function-related quality-of-life concerns after strabismus surgery in nondiplopic adults.
BACKGROUND
We have previously reported improvement in psychosocial scores after strabismus surgery on the patient-derived health-related quality of life (HRQOL) Adult Strabismus 20 (AS-20) questionnaire in adults with nondiplopic strabismus. Unexpectedly, we also found improvement in the function domain. The aim of the present study was to identify which specific aspects of function-related quality of life improved postoperatively.


METHODS
We retrospectively identified non diplopic adult patients with a history of childhood onset strabismus who underwent surgery and who had preoperative and 1-year postoperative AS-20 questionnaires (scored from 0 [worst] to 100 [best]). Change in scores for each item was evaluated using signed-rank tests.


RESULTS
A total of 20 patients were included. Of the 10 function-related AS-20 items, 9 showed significant mean improvement postoperatively (improvement ranged from 12.5 to 32.5 points, all P < 0.05). Rasch-derived mean scores improved in both reading function and general function domains (71.0 to 86.5 and 66.4 to 87.5, respectively; both P < 0.0001). Specific areas of function-related benefit were concentration, depth perception, hobbies, strain, reading, stress, and worry.


CONCLUSIONS
We found specific function-related quality of life benefits after strabismus surgery in nondiplopic adult patients, particularly those with childhood onset strabismus.
Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota.
Laura
L
Liebermann
Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota.
Sarah R
SR
Hatt
Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota.
David A
DA
Leske
Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota. Electronic address: holmes.jonathan@mayo.edu.
Jonathan M
JM
Holmes
D000328:Adult; D000368:Aged; D003867:Depth Perception / Q000502:physiology; D004172:Diplopia / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009801:Oculomotor Muscles / Q000503:physiopathology / Q000601:surgery*; D013508:Ophthalmologic Surgical Procedures; D011788:Quality of Life / Q000523:psychology*; D012189:Retrospective Studies; D018434:Sickness Impact Profile; D013285:Strabismus / Q000503:physiopathology / Q000523:psychology* / Q000601:surgery*; D011795:Surveys and Questionnaires; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult