Brief report: the length of newly diagnosed Barrett's esophagus may be decreasing.
Few studies have examined the temporal trends of length in newly diagnosed Barrett's esophagus (BE) and arrived at conflicting results. The aim of this study was to identify whether there has been a change over time in the length of BE at the time of diagnosis. This is a retrospective, single-center, observational study from Houston, Texas on newly diagnosed BE between 2008 and 2013. All cases were defined by the presence of endoscopically visible BE and histologic confirmation of intestinalized columnar epithelium with goblet cells. The length of BE was measured using the Prague classification. We examined temporal changes in 1-year intervals in the length of BE at the time of diagnosis. Both the frequency and mean length of BE at diagnosis seemed to decrease over time from February 2008 to July 2013. The proportion of patients diagnosed with BE ≥3 cm per year declined during the study period, while the proportion of patients with BE ≥1 and <3 cm increased, and those with <1 cm remained stable. The mean age and the gender of patients diagnosed with BE ≥3 cm did not differ significantly by BE length or year of diagnosis. The mean length of newly diagnosed BE may be decreasing as a result of a decline in BE ≥3 cm. These observations cannot be explained by changes in age and gender.
Houston VA HSR&D Center of Excellence, Baylor College of Medicine, Houston, Texas, USA.|Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
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Nguyen
Houston VA HSR&D Center of Excellence, Baylor College of Medicine, Houston, Texas, USA.
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Alsarraj
Houston VA HSR&D Center of Excellence, Baylor College of Medicine, Houston, Texas, USA.|Department of Medicine, Michael E. DeBakey Veterans Affairs Medical Center, Baylor College of Medicine, Houston, Texas, USA.|Section of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USA.
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El-Serag
D000368:Aged; D001471:Barrett Esophagus / Q000145:classification / Q000453:epidemiology / Q000473:pathology*; D016022:Case-Control Studies; D004945:Esophagoscopy; D004947:Esophagus / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013781:Texas / Q000453:epidemiology
Barrett's esophagus; Veterans Affair; epidemiological study; esophageal adenocarcinoma; length; risk factor