Partial oesophagectomy for giant leiomyoma of the oesophagus: report of 7 cases.
OBJECTIVE
Oesophageal leiomyoma is the most common benign tumour of the oesophagus. The incidence of leiomyomas larger than 10 cm, defined as giant oesophageal leiomyomas (GELs), has been reported in 17% of all cases. Although computed tomographic scan and endoscopy are usually useful for diagnosis, big and symptomatic masses located in the lower mediastinum remain both a diagnostic and therapeutic challenge.


METHODS
We describe our experience in the management of 7 patients (4 males and 3 females, with a mean age of 41 years) with GEL treated in our department. Radical resection was performed in all cases with partial oesophagectomy in order to relieve symptoms and to obtain a definitive diagnosis.


RESULTS
There was no perioperative mortality. The minimum diameter of the tumours was 15 cm and the maximum was 30 cm. Definitive histological examination confirmed the diagnosis of leiomyoma in all cases without any sign of malignancy. No major postoperative complications developed. Minor complications included partial abdominal wound dehiscence in 1 case, and retention of secretions requiring bronchoscopy in 2. The mean length of hospital stay was 12 days (ranging between 9 and 14 days). After a mean follow-up of 5.4 years (ranging between 12 and 2 years), no sign of recurrence was observed.


CONCLUSIONS
Whereas removal of small oesophageal leiomyomas can be performed by simple enucleation by conventional thoracotomy or video-assisted thoracoscopy, partial oesophagectomy is often necessary for giant lesions. Since it is not possible preoperatively to distinguish GEL from leiomyosarcoma when metastases are absent, partial oesophageal resection is not to be considered an overtreatment and radical resection should always be planned. A gastric tube, in our experience employed as an oesophageal substitute, is effective and could reduce the risk of significant postoperative gastro-oesophageal reflux.
Department of Surgery and Transplantation 'P. Stefanini' Thoracic Surgery, University of Rome 'Sapienza', Rome, Italy tiziano.degiacomo@tin.it.
Tiziano
T
De Giacomo
Department of Surgery and Transplantation 'P. Stefanini' Thoracic Surgery, University of Rome 'Sapienza', Rome, Italy.
Pietro
P
Bruschini
Department of Surgery and Transplantation 'P. Stefanini' Thoracic Surgery, University of Rome 'Sapienza', Rome, Italy.
Stefano
S
Arcieri
Department of Surgery and Transplantation 'P. Stefanini' Thoracic Surgery, University of Rome 'Sapienza', Rome, Italy.
Franco
F
Ruberto
Department of Surgery and Transplantation 'P. Stefanini' Thoracic Surgery, University of Rome 'Sapienza', Rome, Italy.
Federico
F
Venuta
Department of Surgery and Transplantation 'P. Stefanini' Thoracic Surgery, University of Rome 'Sapienza', Rome, Italy.
Daniele
D
Diso
Department of Surgery and Transplantation 'P. Stefanini' Thoracic Surgery, University of Rome 'Sapienza', Rome, Italy.
Federico
F
Francioni
D000328:Adult; D004938:Esophageal Neoplasms / Q000601:surgery*; D016629:Esophagectomy / Q000379:methods* / Q000401:mortality; D004947:Esophagus / Q000601:surgery; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000601:surgery*; D007902:Length of Stay; D008297:Male
Leiomyoma; Oesophageal benign tumours; Oesophagectomy; Oesophagus