Parallelized multi-graphics processing unit framework for high-speed Gabor-domain optical coherence microscopy.
Gabor-domain optical coherence microscopy (GD-OCM) is a volumetric high-resolution technique capable of acquiring three-dimensional (3-D) skin images with histological resolution. Real-time image processing is needed to enable GD-OCM imaging in a clinical setting. We present a parallelized and scalable multi-graphics processing unit (GPU) computing framework for real-time GD-OCM image processing. A parallelized control mechanism was developed to individually assign computation tasks to each of the GPUs. For each GPU, the optimal number of amplitude-scans (A-scans) to be processed in parallel was selected to maximize GPU memory usage and core throughput. We investigated five computing architectures for computational speed-up in processing 1000×1000 A-scans. The proposed parallelized multi-GPU computing framework enables processing at a computational speed faster than the GD-OCM image acquisition, thereby facilitating high-speed GD-OCM imaging in a clinical setting. Using two parallelized GPUs, the image processing of a 1×1×0.6  mm3 skin sample was performed in about 13 s, and the performance was benchmarked at 6.5 s with four GPUs. This work thus demonstrates that 3-D GD-OCM data may be displayed in real-time to the examiner using parallelized GPU processing.
University of Rochester, The Institute of Optics, 275 Hutchinson Road, Rochester, New York 14627bUniversity of Rochester, Center for Visual Science, 601 Elmwood Avenue, Rochester, New York 14642.
Patrice
P
Tankam
University of California, Department of Radiation Oncology, Los Angeles, 200 Medical plaza drive, Los Angeles, California 90095.
Anand P
AP
Santhanam
University of Rochester, The Institute of Optics, 275 Hutchinson Road, Rochester, New York 14627dKorea Basic Science Institute, Center for Analytical Instrumentation Development, Daejeon 305-806, South Korea.
Kye-Sung
KS
Lee
University of Rochester, Department of Biomedical Engineering, 275 Hutchinson Road, Rochester, New York 14627.
Jungeun
J
Won
LighTopTech Corp., 150 Lucius Gordon Dr., Ste 115, West Henrietta, New York 14586.
Cristina
C
Canavesi
University of Rochester, The Institute of Optics, 275 Hutchinson Road, Rochester, New York 14627bUniversity of Rochester, Center for Visual Science, 601 Elmwood Avenue, Rochester, New York 14642eUniversity of Rochester, Department of Biomedical Engineerin.
Jannick P
JP
Rolland
D000465:Algorithms; D003196:Computer Graphics; D003199:Computer Systems; D003201:Computers; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional; D008853:Microscopy / Q000379:methods*; D012031:Refractometry; D012867:Skin / Q000473:pathology; D012984:Software; D041623:Tomography, Optical Coherence / Q000379:methods*