MR Quantification of the Fatty Fraction from T2*-corrected Dixon Fat/Water Separation Volume-interpolated Breathhold Examination (VIBE) in the Assessment of Muscle Atrophy in Rotator Cuff Tears.
OBJECTIVE
To assess the usefulness of T2*-corrected fat fraction (FF) map from volume-interpolated breathhold examination (VIBE) magnetic resonance (MR) sequence in patients with the rotator cuff pathology.


METHODS
The phantom study was performed to validate the FF maps. Eighty-nine shoulder MR arthrographies were analyzed: (1) divided into three groups namely tendinopathy/normal tendons, partial-thickness tears, and full-thickness tears, and (2) occupation ratio (OR) was measured for muscular atrophy. Uncorrected and T2*-corrected FF maps were reconstructed from the VIBE images. The Pearson correlation test was used to correlate the FFs with ORs. The FF and the OR were compared between groups using the Student t test.


RESULTS
T2*-corrected FF maps could provide a higher correlation than uncorrected FF maps. There were significantly negative correlations between the ORs and the FFs (P < .01). In the normal and the partial-thickness tear group, the OR did not show a significant difference, although the FF maps showed a significant difference (P < .01).


CONCLUSIONS
This quantitative assessment of the T2*-corrected FF in the rotator cuff muscles was found to be reliable and correlated well with the ORs. The T2*-corrected FF maps could be used for more sophisticated assessments of the fat even in the partial-thickness tear.
Department of Radiology, Research Institute of Radiological Science, Medical Convergence Research Institute, and Severance Biomedical Science Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
Young Han
YH
Lee
Department of Radiology, Research Institute of Radiological Science, Medical Convergence Research Institute, and Severance Biomedical Science Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
Sungjun
S
Kim
Department of Radiology, Research Institute of Radiological Science, Medical Convergence Research Institute, and Severance Biomedical Science Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
Daekeon
D
Lim
Department of Radiology, Research Institute of Radiological Science, Medical Convergence Research Institute, and Severance Biomedical Science Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
Ho-Taek
HT
Song
Department of Radiology, Research Institute of Radiological Science, Medical Convergence Research Institute, and Severance Biomedical Science Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Republic of Korea. Electronic address: jss@yuhs.ac.
Jin-Suck
JS
Suh
D000273:Adipose Tissue / Q000473:pathology*; D050154:Adiposity; D000328:Adult; D000465:Algorithms; D016477:Artifacts; D001834:Body Water; D062485:Breath Holding; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009133:Muscular Atrophy / Q000209:etiology / Q000473:pathology*; D015203:Reproducibility of Results; D017006:Rotator Cuff / Q000473:pathology*; D000070636:Rotator Cuff Injuries; D012680:Sensitivity and Specificity; D013382:Subtraction Technique
Fatty degeneration; fat fraction; fat water separation; occupation ratio; rotator cuff