No monkeying around: clonal tracking of stem cells and progenitors in the macaque.
Clonal tracking of hematopoietic stem and progenitor cells (HSPCs) has proven valuable for studying their behavior in murine recipients. Now in Cell Stem Cell, Kim et al. (2014) and Wu et al. (2014) extend these analyses to nonhuman primates, providing insights into dynamics of HSPC expansion and lineage commitment following autologous transplantation.
Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston MA 02115, USA. Electronic address: bdykstra@partners.org.
Brad
B
Dykstra
Laboratory of Ageing Biology and Stem Cells, European Research Institute for Biology of Ageing, University Medical Center Groningen, University of Groningen, 9700 AD, Groningen, The Netherlands. Electronic address: l.bystrykh@umcg.nl.
Leonid V
LV
Bystrykh
D000818:Animals; D002454:Cell Differentiation; D019070:Cell Lineage; D058948:Cell Tracking; D006410:Hematopoiesis / Q000502:physiology*; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D006801:Humans; D007694:Killer Cells, Natural / Q000166:cytology*; D008214:Lymphocytes / Q000166:cytology*; D022423:Myeloid Cells / Q000166:cytology*