A naphthalimide-based bifunctional fluorescent probe for the differential detection of Hg²⁺ and Cu²⁺ in aqueous solution.
A novel fluorescent probe NPM based on naphthalimide was designed and synthesized. Interestingly, NPM exhibited highly selective fluorescence turn-on for Hg(2+) and turn-off for Cu(2+) in aqueous solution (10 mM HEPES, pH 7.5). Its fluorescence intensity enhanced in a linear fashion with the concentration of Hg(2+) and decreased in a nearly linear fashion with the concentration of Cu(2+). Thus NPM could be potentially used for the quantification of Hg(2+) and Cu(2+) in aqueous solution. A series of model compounds were rationally designed and synthesized in order to explore the sensing mechanisms and binding modes of NPM with Hg(2+) and Cu(2+).
Department of Chemistry, East China Normal University, 3663 N. Zhongshan Road, Shanghai 200062, P. R. China. lxu@chem.ecnu.edu.cn.
Chang-Bo
CB
Huang
Hao-Ran
HR
Li
Yuanyuan
Y
Luo
Lin
L
Xu
D002413:Cations, Divalent / Q000032:analysis; D003300:Copper / Q000032:analysis*; D005456:Fluorescent Dyes / Q000737:chemistry*; D008628:Mercury / Q000032:analysis*; D053644:Naphthalimides / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D014867:Water / Q000032:analysis*
D002413:Cations, Divalent; D005456:Fluorescent Dyes; D053644:Naphthalimides; D014867:Water; D003300:Copper; D008628:Mercury