Biomarkers of peritoneal fluid in endometriosis identified by surface-enhanced laser desorption/ionization time-of-flight.
OBJECTIVE
This work aims to detect the peritoneal fluid proteomic patterns in endometriosis patients, build diagnostic models, and evaluate its clinical significance.


METHODS
The authors used SELDI-TOF-MS protein chip array technology to detect biomarkers of peritoneal fluid in endometriosis patients. Fourteen endometriosis patients and 16 persons without endometriosis as control group were tested.


RESULTS
Four potential biomarkers (4428m/z, 6891m/z, 13766m/z, and 6427m/z) were found.


CONCLUSIONS
This method showed great potential in screening better biomarkers for endometriosis.
L
L
Wang
X Y
XY
Ding
J K
JK
Yu
S Z
SZ
Zhang
W
W
Zheng
D000328:Adult; D001202:Ascitic Fluid / Q000737:chemistry*; D015415:Biomarkers / Q000032:analysis*; D004715:Endometriosis / Q000175:diagnosis* / Q000378:metabolism; D005260:Female; D006801:Humans; D040081:Protein Array Analysis / Q000379:methods; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D055815:Young Adult
D015415:Biomarkers