Monte Carlo simulation of optical coherence tomography for turbid media with arbitrary spatial distributions.
We developed a Monte Carlo-based simulator of optical coherence tomography (OCT) imaging for turbid media with arbitrary spatial distributions. This simulator allows computation of both Class I diffusive reflectance due to ballistic and quasiballistic scattered photons and Class II diffusive reflectance due to multiple scattered photons. It was implemented using a tetrahedron-based mesh and importance sampling to significantly reduce computational time. Our simulation results were verified by comparing them with results from two previously validated OCT simulators for multilayered media. We present simulation results for OCT imaging of a sphere inside a background slab, which would not have been possible with earlier simulators. We also discuss three important aspects of our simulator: (1) resolution, (2) accuracy, and (3) computation time. Our simulator could be used to study important OCT phenomena and to design OCT systems with improved performance.
University of Manitoba, Department of Electrical and Computer Engineering, 75A Chancellor's Circle, Winnipeg, Manitoba R3T 5V6, Canada.
Siavash
S
Malektaji
North Dakota State University, Department of Electrical and Computer Engineering, 1411 Centennial Boulevard, Fargo, North Dakota 58108-6050.
Ivan T
IT
Lima
University of Manitoba, Department of Electrical and Computer Engineering, 75A Chancellor's Circle, Winnipeg, Manitoba R3T 5V6, Canada.
Sherif S
SS
Sherif
D003198:Computer Simulation; D008954:Models, Biological; D009010:Monte Carlo Method; D017785:Photons; D041623:Tomography, Optical Coherence