Diagnosis of osteosarcoma in a patient previously treated for Ewing sarcoma.
Primary malignant bone tumors, whether Ewing sarcoma or osteosarcoma, are a rare type of tumor. The sequential occurrence of two bone sarcomas, Ewing sarcoma and high-grade osteosarcoma, in the same patient at two different locations is an exceptionally rare phenomenon. We present the case of a 13-year-old girl who presented with a high-grade osteoblastic osteosarcoma of the distal femur, 7 years after treatment for Ewing sarcoma of the left pelvis. She did not receive radiation therapy. Following the recent developing multidisciplinary therapy, long-term follow-up for monitoring latent treatment-related adverse effects may be necessary for survivors of primary malignant bone tumors.
Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-Machi, Abeno-Ku, Osaka, 545-8585, Japan, hoshi@med.osaka-cu.ac.jp.
Manabu
M
Hoshi
Makoto
M
Ieguchi
Kazumi
K
Yamato
Sadao
S
Tokimasa
Hiroaki
H
Nakamura
D000293:Adolescent; D002648:Child; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D005266:Femoral Neoplasms / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D016609:Neoplasms, Second Primary / Q000175:diagnosis* / Q000628:therapy; D012516:Osteosarcoma / Q000175:diagnosis* / Q000628:therapy; D010384:Pelvic Bones / Q000473:pathology*; D012512:Sarcoma, Ewing / Q000175:diagnosis* / Q000628:therapy; D014057:Tomography, X-Ray Computed