Exploring the anionic reactivity of ynimines, useful precursors of metalated ketenimines.
Insights into the reactivity of ynimines under anionic conditions are reported. They were shown to be excellent precursors of metalated ketenimines, which can be generated in situ by the reaction of ynimines with organolithium reagents or strong bases. The metalated ketenimines can then be trapped with various electrophiles and, depending on their substitution pattern, afford original and divergent entries to various building blocks.
Institut Lavoisier de Versailles, UMR CNRS 8180, Université de Versailles Saint-Quentin-en-Yvelines , 45, Avenue des Etats-Unis, 78035 Versailles Cedex, France.
Anouar
A
Laouiti
François
F
Couty
Jérome
J
Marrot
Taoufik
T
Boubaker
Mohamed M
MM
Rammah
Mohamed B
MB
Rammah
Gwilherm
G
Evano