Interactions between commonly used left and right ventricular function indexes in stable patients.
OBJECTIVE
Aim of this study was to better understand interactions between left ventricular (LV) and right ventricular (RV) systolic and diastolic function echocardiographic indexes in stable cardiovascular diseased patients and in subjects with cardiovascular risk factors.


METHODS
The study enrolled 683 stable patients who were submitted to standard transthoracic echocardiography with evaluation of left ventricular ejection fraction (LVEF) (Simpson biplane method), LV and RV systolic peak on Doppler tissue imaging (LVSys and RVSys), tricuspid annulus plane systolic excursion (TAPSE), pulmonary artery systolic pressure (PASP), and multiparameter evaluation of LV and RV diastolic function utilizing E and A peak, their ratio, E peak deceleration time, E' and A' peak on Doppler tissue imaging, their ratio, and E/E' ratio.


RESULTS
Part of the considered indexes had interactions but only LVEF and TAPSE were related to all the others (LVEF P<0.001 with all the considered parameters; TAPSE P<0.001 with all parameters except with PASP=0.003). Unexpectedly TAPSE seems to have, such as LVEF, a pivotal position among LV and RV function.


CONCLUSIONS
The study demonstrates the existence of interactions between LV and RV function indexes; these results may be considered as a piece of evidence in favor of heart seen as a single structure.
Cardiovascular Medicine Nuovo Ospedale S. Agostino‑Estense Modena, Italy - p.giovanardi@ausl.mo.it.
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P
Giovanardi
G
G
Stefanelli
F
F
Turrini
L
L
Sarti
F
F
Lami
S
S
Scarlini
F
F
Scaglioni
S
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Tondi
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Bondi
D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000503:physiopathology*; D018619:Echocardiography, Doppler, Pulsed / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D016277:Ventricular Function, Left; D016278:Ventricular Function, Right