Highly emissive water-soluble tetraazaperopyrenes as fluorescent markers.
Water-soluble tetraazaperopyrene (TAPP) derivatives have been synthesized, which show both high photostability and high fluorescence quantum yields (>80%) in water. Furthermore delivery of the dye into cells demonstrated selective staining of the nucleus.
Anorganisch-Chemisches-Institut, Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany. lutz.gade@uni-hd.de.
Lena
L
Hahn
Simin
S
Öz
Hubert
H
Wadepohl
Lutz H
LH
Gade
D002467:Cell Nucleus / Q000737:chemistry; D002470:Cell Survival / Q000187:drug effects; D018360:Crystallography, X-Ray; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity; D006367:HeLa Cells; D006801:Humans; D018613:Microscopy, Confocal; D008968:Molecular Conformation; D011721:Pyrenes / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity; D011789:Quantum Theory; D012995:Solubility; D014867:Water / Q000737:chemistry
D005456:Fluorescent Dyes; D011721:Pyrenes; D014867:Water