Tacalcitol in the treatment of acquired perforating collagenosis.
Acquired perforating collagenosis (APC) is a rare perforating dermatosis characterized by transepidermal collagen elimination. We describe a 65-year-old patient, with long-standing type 2 diabetes mellitus and a 2-year history of itchy hyperkeratotic nodules situated on the back, who was subsequently diagnosed with APC. Treatment included topical corticosteroids and antihistamines, without improvement of the lesions. However, therapy with topical tacalcitol administered for 2 months produced a significant response leading to complete remission of APC.
Dermatology Department, Elx/Elche General University Hospital, Elx/Elche, Spain.
J C
JC
Escribano-Stablé
Dermatology Department, Elx/Elche General University Hospital, Elx/Elche, Spain.
C
C
Doménech
Dermatology Department, Elx/Elche General University Hospital, Elx/Elche, Spain.
J
J
Matarredona
Dermatology Department, Elx/Elche General University Hospital, Elx/Elche, Spain.
J C
JC
Pascual
Dermatology Department, Elx/Elche General University Hospital, Elx/Elche, Spain.
A
A
Jaen
Dermatology Department, Elx/Elche General University Hospital, Elx/Elche, Spain.
J
J
Vicente
Acquired perforating collagenosis; Elastosis perforans serpiginosa; Perforating collagenosis; Tacalcitol; Vitamin D3 analogues