Obstructive small bowel metastasis from uterine leiomyosarcoma: a case report.
Background. Uterine leiomyosarcoma is a rare and aggressive gynecologic malignancy with an overall poor prognosis. Lungs, bones, and brain are common sites of metastases of uterine leiomyosarcoma. Metastases of uterine leiomyosarcoma to the small bowel are extremely rare, and only four case reports have been published to date. Case presentation. A 55-year-old Saudi woman diagnosed with a case of uterine leiomyosarcoma treated with total abdominal hysterectomy (TAH) and bilateral salpingooophorectomy (BSO) presented in emergency room after sixteen months with acute abdomen. Subsequent work-up showed a jejunal mass for which resection and end-to-end anastomosis were performed. Biopsy confirmed the diagnosis of small bowel metastasis from uterine leiomyosarcoma. Further staging work-up showed wide spread metastasis in lungs and brain. After palliative cranial irradiation, systemic chemotherapy based on single agent doxorubicin was started. Conclusion. Metastatic leiomyosarcoma of small bowel from uterine leiomyosarcoma is a rare entity and is sign of advanced disease. It should be differentiated from primary leiomyosarcoma of small bowel as both are treated with different systemic chemotherapeutic agents.
Radiation Oncology, King Fahad Medical City, Riyadh, Saudi Arabia.
Mutahir A
MA
Tunio
Radiation Oncology, Comprehensive Cancer Center, King Fahad Medical City, Riyadh 59046, Saudi Arabia.
Mushabbab
M
Alasiri
Medical Oncology, Comprehensive Cancer Center, King Fahad Medical City, Riyadh 59046, Saudi Arabia.
Rasha M
RM
Saleh
Radiation Oncology, King Fahad Medical City, Riyadh 59046, Saudi Arabia.
Shomaila Amir
SA
Akbar
Anatomic Pathology, King Fahad Medical City, Riyadh 11525, Saudi Arabia.
Nagoud M
NM
Ali
Clinical Oncology, Minia Oncology Center, Minia, Egypt.
Mohamed Abdalazez
MA
Senosy Hassan