Diabetic myonecrosis: uncommon complications in common diseases.
We report a case of sudden thigh pain from spontaneous quadriceps necrosis, also known as diabetic myonecrosis, in a 28-year-old patient with poorly controlled diabetes mellitus. Diabetic muscle infarction is a rare end-organ complication seen in patients with poor glycemic control and advanced chronic microvascular complications. Proposed mechanisms involve atherosclerotic microvascular occlusion, ischemia-reperfusion related injury, vasculitis with microthrombi formation, and an acquired antiphospholipid syndrome. Diabetic myonecrosis most commonly presents as sudden thigh pain with swelling and should be considered in any patient who has poorly controlled diabetes mellitus.
Department of Medicine, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, NY 11554, USA.
Sisira
0000-0001-9004-3992
S
Sran
Department of Medicine, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, NY 11554, USA.
Manpreet
M
Sran
New York Institute of Technology, College of Osteopathic Medicine, Northern Boulevard, P.O. Box 8000, Old Westbury, NY 11568-8000, USA ; New York Institute of Technology, College of Osteopathic Medicine, Nassau University Medical Center, East Meadow, NY 11554, USA.
Nicole
N
Ferguson
Department of Rheumatology, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, NY 11554, USA.
Prachi
0000-0002-1756-1424
P
Anand