[Effects of carbon components of fine particulate matter (PM2.5) on atherogenic index of plasma].
OBJECTIVE
To evaluate associations between carbon constituents of fine particulate matter (PM2.5) and atherogenic index of plasma (AIP).


METHODS
We collected subjects from two communities by a system sampling, and 112 people aged over 60 years old without cardiovascular disease were recruited. The levels of cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) of objects, and personal exposure to PM2.5 were measured on December, 2011. Total carbon (TC), organic carbon (OC) and elemental carbon (EC) of PM2.5 were detected and AIP was calculated according to its definition.


RESULTS
The value of AIP among the 112 subjects was 0.05 ± 0.26. Personal exposure concentration of PM2.5 and its carbon components (TC,OC and EC) were (164.75 ± 110.67), (53.86 ± 29.65), (44.93 ± 26.37) and (9.49 ± 5.75) µg/m(3), respectively. The Pearson analysis showed the linear relationship between TC,OC,EC and AIP, all significant positive correlations. The correlation coefficients were TC (r = 0.307, P < 0.05),OC (r = 0.287, P < 0.05) and EC (r = 0.252, P < 0.05), respectively. The multiple logistic regression analysis showed that when the AIP risk categories were selected as dependent variable and low risk group as reference group, the regression coefficient of TC,OC and EC was separately 1.03 (95%CI:1.01-1.05), 1.03 (95%CI:1.01-1.05), 1.12 (95%CI:1.02-1.22) in the high risk group; while there was no statistical significance of the regression coefficient and OR in the middle risk group.


CONCLUSIONS
There was stable associations between the carbon constituents (TC,OC and EC) of fine Particulate Matter (PM2.5) and AIP. The findings suggested that carbon components of PM2.5 should be considered as risk factors of atherogenic.
Department of Occupational and Enviromental Health, College of Public Health, Tianjin Medical University, Tianjin 300070, China.
Jiao
J
Fan
Xiaolei
X
Qin
Xiaodan
X
Xue
Bin
B
Han
Zhipeng
Z
Bai
Naijun
N
Tang
Email: zhangliwen@tijmu.edu.cn.
Liwen
L
Zhang
D000368:Aged; D000393:Air Pollutants / Q000032:analysis*; D000397:Air Pollution / Q000009:adverse effects; D050197:Atherosclerosis / Q000175:diagnosis / Q000453:epidemiology; D002244:Carbon / Q000032:analysis*; D002784:Cholesterol / Q000097:blood; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010316:Particle Size; D052638:Particulate Matter / Q000032:analysis*; D018570:Risk Assessment; D014280:Triglycerides / Q000097:blood
D000393:Air Pollutants; D052638:Particulate Matter; D014280:Triglycerides; D002244:Carbon; D002784:Cholesterol