[Differentiation of influenza (Flu) type A, type B, and respiratory syncytial virus (RSV) by QuickNavi™-Flu+RSV].
Because it is not easy to differentiate Influenza virus (Flu) from RS virus (RSV) just by clinical symptoms, to accurately diagnose those viruses in conjunction with patient's clinical symptoms, rapid diagnostic kits has been used separately for each of those viruses. In our new study, we have developed a new rapid diagnostic kit, QuickNavi™-Flu+RSV. The kit can detect Flu A, Flu B, and RSV antigens with a single sample collection and an assay. Total of 2,873 cases (including nasopharyngeal swabs and nasopharyngeal aspirates specimens) in 2010/2011 and 2011/2012 seasons were evaluated with QuickNavi™-Flu+RSV and a commercially available kit. Sensitivity, specificity, and accuracy of Flu type A, type B, and RSV were above 95% when compared to commercially available kits (QuickNavi™-Flu and QuickNavi™-RSV) and considered to be equivalent to the commercially available kits. In 2011/2012 season, RSV infections increased prior to Flu season and continued during the peak of the Flu season. The kit can contribute to accurate diagnosis of Flu and RSV infections since co-infection cases have also been reported during the 2011/2012 season. QuickNavi™-Flu+RSV is useful for differential diagnosis of respiratory infectious diseases since it can detect Flu type A, type B, and RSV virus antigens with a single sample collection.
Reagent R&D Department, Denka Seiken Co., Ltd., 1359-1 Kagamida, Kigoshi-aza, Gosen, Niigata 959-1695, Japan.
Risa
R
Kohiyama
Reagent R&D Department, Denka Seiken Co., Ltd., 1359-1 Kagamida, Kigoshi-aza, Gosen, Niigata 959-1695, Japan.
Takashi
T
Miyazawa
Reagent R&D Department, Denka Seiken Co., Ltd., 1359-1 Kagamida, Kigoshi-aza, Gosen, Niigata 959-1695, Japan.
Nobuko
N
Shibano
Reagent R&D Department, Denka Seiken Co., Ltd., 1359-1 Kagamida, Kigoshi-aza, Gosen, Niigata 959-1695, Japan.
Koichi
K
Inano
D000956:Antigens, Viral / Q000032:analysis; D003937:Diagnosis, Differential; D006801:Humans; D007251:Influenza, Human / Q000175:diagnosis; D029521:Alphainfluenzavirus / Q000302:isolation & purification*; D029524:Betainfluenzavirus / Q000302:isolation & purification*; D008828:Microbiological Techniques / Q000295:instrumentation*; D011933:Reagent Kits, Diagnostic; D018357:Respiratory Syncytial Virus Infections / Q000175:diagnosis; D012136:Respiratory Syncytial Viruses / Q000302:isolation & purification*; D012680:Sensitivity and Specificity
D000956:Antigens, Viral; D011933:Reagent Kits, Diagnostic