Hypertrophic pyloric stenosis in twins; genetic or environmental factors.
The etiology of infantile hypertrophic pyloric stenosis (IHPS) remains obscure. Over 120 years after the condition has become a clinical entity the debate whether the cause of IHPS is genetic, environmental or both, has not yet reached a final conclusion. Herein, we present a pair of monozygotic male twins with IHPS together with a review of the literature. We aimed to support genetic pre-disposition in the epidemiology of IHPS, adding a twin data to the literature and to review the associated articles about the pathogenesis and inheritance patterns.
Başkent University Faculty of Medicine, Department of Pediatric Surgery, Ankara, Turkey.
H Ö
HÖ
Gezer
P
P
Oguzkurt
A
A
Temiz
A
A
Hicsonmez
D004200:Diseases in Twins / Q000235:genetics* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D046248:Pyloric Stenosis, Hypertrophic / Q000235:genetics* / Q000473:pathology* / Q000601:surgery; D014430:Twins, Monozygotic / Q000235:genetics*
etiology; genetic; hypertrophic; pyloric; stenosis