Ultrasound measurements of brain tissue pulsatility correlate with the volume of MRI white-matter hyperintensity.
White-matter hyperintensity (WMH) is frequently seen in magnetic resonance imaging (MRI), but the complete physiopathology of WMH remains to be elucidated. In this study, we sought to determine whether there is an association between the maximum brain tissue displacement (maxBTD), as assessed by ultrasound, and the WMH, as observed by MRI. Nine healthy women aged 60 to 85 years underwent ultrasound and MRI assessments. We found a significant negative correlation between maxBTD and WMH (ρ=-0.86, P<0.001), suggesting a link between cerebral hypoperfusion and WMH.
1] UMR Inserm U930 Imagerie et Cerveau, Tours, France [2] Université François Rabelais de Tours, Tours, France.
Redouane
R
Ternifi
CHRU de Tours Department of Clinique Psychiatrique and Department of Imaging, Tours, France.
Xavier
X
Cazals
1] UMR Inserm U930 Imagerie et Cerveau, Tours, France [2] CHRU de Tours Department of Clinique Psychiatrique and Department of Imaging, Tours, France.
Thomas
T
Desmidt
UMR Inserm U930 Imagerie et Cerveau, Tours, France.
Frédéric
F
Andersson
1] UMR Inserm U930 Imagerie et Cerveau, Tours, France [2] Université François Rabelais de Tours, Tours, France [3] CHRU de Tours Department of Clinique Psychiatrique and Department of Imaging, Tours, France [4] INSERM CIC 1415, Tours, France.
Vincent
V
Camus
1] UMR Inserm U930 Imagerie et Cerveau, Tours, France [2] Université François Rabelais de Tours, Tours, France [3] CHRU de Tours Department of Clinique Psychiatrique and Department of Imaging, Tours, France.
Jean-Philippe
JP
Cottier
1] UMR Inserm U930 Imagerie et Cerveau, Tours, France [2] Université François Rabelais de Tours, Tours, France [3] CHRU de Tours Department of Clinique Psychiatrique and Department of Imaging, Tours, France [4] INSERM CIC 1415, Tours, France.
Frédéric
F
Patat
1] UMR Inserm U930 Imagerie et Cerveau, Tours, France [2] Université François Rabelais de Tours, Tours, France.
Jean-Pierre
JP
Remenieras
D000368:Aged; D000369:Aged, 80 and over; D002540:Cerebral Cortex / Q000098:blood supply / Q000000981:diagnostic imaging; D002560:Cerebrovascular Circulation / Q000502:physiology*; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D011673:Pulsatile Flow / Q000502:physiology*; D011859:Radiography; D014463:Ultrasonography