Redux valvular surgery with coronary artery bypass graft in familial hypercholesterolemia.
Familial hypercholesterolemia (FH) is a dominantly inherited disorder caused by mutation at the locus for the low-density lipoprotein (LDL) receptor and is frequently associated with premature coronary artery disease and aortic valve involvement. The surgical treatment of these complications is accompanied by a high degree of risk, even in skillful hands. An intensive cholesterol-lowering therapy and LDL aphaeresis in association with surgery may be useful. The case of a 12-year-old girl, with a medical history of familial hypercholesterolemia is reported here, operated two years previously for valvular aortic stenosis; Ross intervention was done. She was readmitted for acute coronary syndrome. Three coronary artery bypass grafting was performed with saphenous veins with positive results.
Department of Cardiovascular and Thoracic, Rabta Hospital, Medical University of Tunis, Tunis, Tunisia.
Ziadi
Z
Jalel
Department of Cardiovascular and Thoracic, Rabta Hospital, Medical University of Tunis, Tunis, Tunisia.
Mleyhi
M
Sobhi
Department of Cardiovascular and Thoracic, Rabta Hospital, Medical University of Tunis, Tunis, Tunisia.
Ben Omrane
BO
Skander
Department of Cardiovascular and Thoracic, Rabta Hospital, Medical University of Tunis, Tunis, Tunisia.
Khayati
K
Adel
Coronary artery bypass graft; hypercholesterolemia; pediatric