Breast cancer version 3.2014.
Breast cancer is the most common malignancy in women in the United States and is second only to lung cancer as a cause of cancer death. The overall management of breast cancer includes the treatment of local disease with surgery, radiation therapy, or both, and the treatment of systemic disease with cytotoxic chemotherapy, endocrine therapy, biologic therapy, or combinations of these. The NCCN Guidelines specific to management of large clinical stage II and III tumors are discussed in this article. These guidelines are the work of the members of the NCCN Breast Cancer Panel. Expert medical clinical judgment is required to apply these guidelines in the context of an individual patient to provide optimal care. Although not stated at every decision point of the guidelines, patient participation in prospective clinical trials is the preferred option of treatment for all stages of breast cancer.
William J
WJ
Gradishar
Benjamin O
BO
Anderson
Sarah L
SL
Blair
Harold J
HJ
Burstein
Amy
A
Cyr
Anthony D
AD
Elias
William B
WB
Farrar
Andres
A
Forero
Sharon Hermes
SH
Giordano
Lori J
LJ
Goldstein
Daniel F
DF
Hayes
Clifford A
CA
Hudis
Steven J
SJ
Isakoff
Britt-Marie E
BM
Ljung
P Kelly
PK
Marcom
Ingrid A
IA
Mayer
Beryl
B
McCormick
Robert S
RS
Miller
Mark
M
Pegram
Lori J
LJ
Pierce
Elizabeth C
EC
Reed
Kilian E
KE
Salerno
Lee S
LS
Schwartzberg
Mary Lou
ML
Smith
Hatem
H
Soliman
George
G
Somlo
John H
JH
Ward
Antonio C
AC
Wolff
Richard
R
Zellars
Dorothy A
DA
Shead
Rashmi
R
Kumar
D001943:Breast Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D005260:Female; D006801:Humans