A simple and efficient approach to realize difunctionalization of arylketones with malonate esters via electrochemical oxidation.
A facile difunctionalization of arylketones with malonate esters via electrochemical oxidation was achieved under mild conditions. A variety of difunctionalized products were obtained in good to excellent yields.
Hefei National Laboratory for Physical Sciences at Microscale, CAS Key Laboratory of Soft Matter Chemistry & Collaborative Innovation Center of Suzhou Nano Science and Technology, University of Science and Technology of China, Hefei, 230026, P. R. China. zwang3@ustc.edu.cn.
Huihui
H
Gao
Zhenggen
Z
Zha
Zhenlei
Z
Zhang
Huanyue
H
Ma
Zhiyong
Z
Wang