Tolerance induction in hypersensitivity reactions from drugs: a brief overview.
Drug hypersensitivity reactions can occur with many drugs, are unpredictable, may affect any organ system and range widely in clinical severity from mild pruritus to exanthems to anaphylaxis. In most cases, the suspected drug must be avoided in the future. However, for certain patients, the particular drug may be essential for an optimal therapy. Under these circumstances, desensitization may be performed.
Allergy Unit, Dermatology Clinic, University Hospital Basel, Petersgraben 4 CH-4031 Basel Switzerland.
Andreas J
AJ
Bircher
Allergy Unit, Dermatology Clinic, University Hospital Basel, Petersgraben 4 CH-4031 Basel Switzerland.
Katrin
K
Scherer Hofmeier
D003888:Desensitization, Immunologic; D004342:Drug Hypersensitivity / Q000276:immunology / Q000628:therapy*; D006801:Humans
desensitization; drug hypersensitivity; tolerance induction