A new triterpenoid glycoside from Vitex negundo.
OBJECTIVE
To investigate the chemical constituents of Vitex negundo.


METHODS
Compounds were isolated by different chromatographic methods and their structures were elucidated on the basis of NMR spectroscopy.


RESULTS
Four compounds were isolated and identified as 2α, 3α, 24-trihydroxyurs-12, 20(30)-dien-28-oic acid-28-O-β-D-glucopyranosyl ester (1), corosolic acid (2), vulgarsaponin A (3) and 2α, 3α, 24-trihydroxyurs-12-en-28-oic acid-28-O-β-Dglucopyranosyl ester (4), respectively.


CONCLUSIONS
Compound 1 is a new triterpenoid glycoside.
Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009, China.
Jiao
J
Chen
Institute of Traditional Chinese Medicine & Natural Products, Jinan University, Guangzhou 510632, China; JNU-HKUST Joint Laboratory for Neuroscience & Innovative Drug Research, Jinan University, Guangzhou 510632, China.
Chun-Lin
CL
Fan
Institute of Traditional Chinese Medicine & Natural Products, Jinan University, Guangzhou 510632, China; JNU-HKUST Joint Laboratory for Neuroscience & Innovative Drug Research, Jinan University, Guangzhou 510632, China. Electronic address: wangying_cpu@163.com.
Ying
Y
Wang
Institute of Traditional Chinese Medicine & Natural Products, Jinan University, Guangzhou 510632, China; JNU-HKUST Joint Laboratory for Neuroscience & Innovative Drug Research, Jinan University, Guangzhou 510632, China. Electronic address: chywc@yahoo.com.cn.
Wen-Cai
WC
Ye
D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification; D020950:Vitex / Q000737:chemistry*
D010936:Plant Extracts; D012503:Saponins; D014315:Triterpenes; C113861:corosolic acid
2α, 3α, 24-Trihydroxyurs-12, 20(30)-dien-28-oic acid-28-O-β-D-glucopyranosyl ester; Triterpenoid glycosides; Vitex negundo