Steroidal saponins from the roots of Asparagus cochinchinensis.
OBJECTIVE
To study the chemical constituents of the roots of Asparagus cochinchinensis (Asparagaceae).


METHODS
The compounds were isolated with Diaion HP20, silica gel, and ODS chromatography, and their structures were determined on the basis of chemical methods, HR-ESI-MS, and 1D- and 2D-NMR techniques.


RESULTS
Seven compounds were isolated from the n-butanol fraction of the roots of A. cochinchinensis, and their structures were elucidated as (25S)-26-O-β-D-glucopyranosyl-5β-furostan-3β, 22α, 26-triol-12-one-3-O-β-D-glucopyranoside (1), (25S)-26-O-β-D-glucopyranosyl-22α-methoxy-5β-furostan-3β, 26-diol-12-one-3-O-β-D-glucopyranoside (2), (25S)-26-O-β-D-glucopyranosyl-5β-furostan-3β, 22α, 26-triol (3), (25S)-26-O-β-D-glucopyranosyl-5β-furstan-3β, 22α, 26-triol-3-O-β-D-glucopyranoside (4), (25S)-26-O-β-D-glucopyranosyl-5β-furostan-3β, 22α, 26-triol-3-O-α-L-rhamnopyranosyl-(1, 4)-β-D-glucopyranoside (5), (25S)-5β-spirostan-3β-ol-3-O-α-L-rhamnopyranoside (6), and (25S)-5β-spirostan-3β-ol-3-O-β-D-glucopyranoside (7).


CONCLUSIONS
Compounds 1 and 2 were two new furostanol saponins.
Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Guo-Lei
GL
Zhu
Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Qian
Q
Hao
Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Rong-Tao
RT
Li
Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China. Electronic address: lihaizhou@yninfo.com.
Hai-Zhou
HZ
Li
D027761:Asparagus Plant / Q000737:chemistry*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*
D010936:Plant Extracts; D012503:Saponins
Asparagaceae; Asparagus cochinchinensis; Steroidal saponins