Engineering multifunctional capsules through the assembly of metal-phenolic networks.
Metal-organic coordination materials are of widespread interest because of the coupled benefits of inorganic and organic building blocks. These materials can be assembled into hollow capsules with a range of properties, which include selective permeability, enhanced mechanical/thermal stability, and stimuli-responsiveness. Previous studies have primarily focused on the assembly aspects of metal-coordination capsules; however, the engineering of metal-specific functionality for capsule design has not been explored. A library of functional metal-phenolic network (MPN) capsules prepared from a phenolic ligand (tannic acid) and a range of metals is reported. The properties of the MPN capsules are determined by the coordinated metals, allowing for control over film thickness, disassembly characteristics, and fluorescence behavior. Furthermore, the functional properties of the MPN capsules were tailored for drug delivery, positron emission tomography (PET), magnetic resonance imaging (MRI), and catalysis. The ability to incorporate multiple metals into MPN capsules demonstrates that a diverse range of functional materials can be generated.
Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria 3010 (Australia).
Junling
J
Guo
Yuan
Y
Ping
Hirotaka
H
Ejima
Karen
K
Alt
Mirko
M
Meissner
Joseph J
JJ
Richardson
Yan
Y
Yan
Karlheinz
K
Peter
Dominik
D
von Elverfeldt
Christoph E
CE
Hagemeyer
Frank
F
Caruso
D000818:Animals; D002214:Capsules / Q000737:chemistry*; D002384:Catalysis; D002460:Cell Line; D003287:Contrast Media / Q000138:chemical synthesis / Q000737:chemistry; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry; D008279:Magnetic Resonance Imaging; D008670:Metals / Q000737:chemistry*; D051379:Mice; D010539:Permeability; D010636:Phenols / Q000737:chemistry*; D059808:Polyphenols / Q000737:chemistry; D049268:Positron-Emission Tomography; D013634:Tannins / Q000737:chemistry; D014057:Tomography, X-Ray Computed
D002214:Capsules; D003287:Contrast Media; D056831:Coordination Complexes; D008670:Metals; D010636:Phenols; D059808:Polyphenols; D013634:Tannins
coordination; fluorescence; multifunctional capsules; organic-inorganic hybrid materials; polyphenols