Metabolic imaging of ischemic stroke: the present and future.
Measures of cerebral metabolism may be useful in the selection of patients for reperfusion therapies and as end points in clinical trials. However, there are currently no clinically routine techniques that provide such data directly. We review how imaging modalities in current clinical use may provide surrogate markers of metabolic activity. Promising techniques for metabolic imaging that are currently in the pipeline are reviewed.
From the Institute of Neurosciences and Psychology (K.A.D.), University of Glasgow, Institute of Neurological Sciences, Glasgow, United Kingdom.
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Dani
Department of Neurology and Neurotherapeutics (S.W.), UT Southwestern, Dallas, Texas. swarach@seton.org.
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Warach
D015415:Biomarkers / Q000378:metabolism; D001921:Brain / Q000378:metabolism*; D002545:Brain Ischemia / Q000175:diagnosis* / Q000378:metabolism*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D020521:Stroke / Q000175:diagnosis* / Q000378:metabolism*
D015415:Biomarkers