Hypercalcaemia and acute kidney injury following administration of vitamin D in granulomatous disease.
Vitamin D deficiency is common. It causes osteomalacia, may contribute to osteoporosis and is an independent risk factor for cancer, diabetes, multiple sclerosis, cardiovascular disease and all-cause mortality. We describe patients with a history of sarcoidosis who developed acute kidney injury due to hypercalcaemia following treatment with colecalciferol.
Renal Unit, Lancashire Teaching Hospitals, Royal Preston Hospital, Lancashire, UK.
James
J
Tollitt
Laurie
L
Solomon
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000328:Adult; D002762:Cholecalciferol / Q000009:adverse effects*; D006801:Humans; D006934:Hypercalcemia / Q000139:chemically induced*; D008297:Male; D012507:Sarcoidosis / Q000150:complications*; D014808:Vitamin D Deficiency / Q000150:complications / Q000188:drug therapy*; D014815:Vitamins / Q000009:adverse effects*
D014815:Vitamins; D002762:Cholecalciferol