Comparison of cure rates and durations of treatment with diphenylcyclopropenone immunotherapy for warts in children/adolescents and adults.
BACKGROUND
Immunotherapy has been used for many years in the treatment of warts. Diphenylcyclopropenone is frequently used as an immunotherapeutic agent.


METHODS
A total of 143 patients with 180 cases of warts were included in this study. We divided the patients into two groups: 72 children/adolescents and 71 adults aged 20 and over. We evaluated two types of sensitization reaction, using an erythema and blister index and a pruritus index.


RESULTS
Of the 180 cases of warts, 159 (88.3%) were completely cured: 86 (92.5%) of the 93 cases in children/adolescents and 73 (83.9%) of the 87 cases in adults. The time required for complete cure was 17.72 ± 2.69 weeks in children/adolescents and 22.92 ± 2.59 weeks in adults (P < 0.05).


CONCLUSIONS
Diphenylcyclopropenone immunotherapy can be used effectively for both children/adolescents and adults. The time required for complete cure is shorter in children/adolescents than in adults.
Department of Dermatology, Hanyang University Guri Hospital, Guri, Korea.
Ho Song
HS
Kang
Min Won
MW
Lee
Jun Oh
JO
Paek
Hee Joon
HJ
Yu
Joung Soo
JS
Kim
D000293:Adolescent; D000328:Adult; D002648:Child; D003521:Cyclopropanes / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007167:Immunotherapy; D008297:Male; D012074:Remission Induction; D012871:Skin Diseases / Q000188:drug therapy*; D013997:Time Factors; D014860:Warts / Q000188:drug therapy*; D055815:Young Adult
D003521:Cyclopropanes; C029402:diphenylcyclopropenone