Symptomatic venous thromboembolism in orthognathic surgery and distraction osteogenesis: a retrospective cohort study of 4127 patients.
Venous thromboembolism is a common postoperative complication, and orthopaedic procedures are particularly at risk. We designed a retrospective, single centre, observational, cohort study of 4127 patients (mean (SD) age 27 (11) years) who had elective orthognathic operations or distraction osteogenesis between January 1970 and February 2012 at the VU University Medical Centre, Amsterdam, to investigate the incidence in this group over the 42-year period, 2 patients developed symptomatic venous thromboembolism (1 woman had a deep vein thrombosis (DVT) and 1 man had a DVT and pulmonary embolus) postoperatively. In relatively young patients with low to moderate risk factors and short hospital stay this type of operation is associated with a particularly low risk of developing thrombosis. It could be advisable to limit the use of thromboprophylaxis to patients at high risk or according to hospital guidelines.
VU University Medical Center, Department of Oral and Maxillofacial Surgery/ Oral Pathology and Academic Centre of Dentistry Amsterdam (ACTA), Amsterdam, the Netherlands. Electronic address: charlotteverlinden@hotmail.com.
Charlotte R A
CR
Verlinden
VU University Medical Center, Department of Oral and Maxillofacial Surgery/ Oral Pathology and Academic Centre of Dentistry Amsterdam (ACTA), Amsterdam, the Netherlands.
Dirk B
DB
Tuinzing
VU University Medical Center, Department of Oral and Maxillofacial Surgery/ Oral Pathology and Academic Centre of Dentistry Amsterdam (ACTA), Amsterdam, the Netherlands.
Tymour
T
Forouzanfar
D000328:Adult; D000367:Age Factors; D015331:Cohort Studies; D017558:Elective Surgical Procedures / Q000706:statistics & numerical data; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D063168:Mandibular Osteotomy / Q000706:statistics & numerical data; D063166:Maxillary Osteotomy / Q000706:statistics & numerical data; D008875:Middle Aged; D009426:Netherlands / Q000453:epidemiology; D061646:Operative Time; D056948:Orthognathic Surgical Procedures / Q000706:statistics & numerical data*; D019857:Osteogenesis, Distraction / Q000706:statistics & numerical data*; D011183:Postoperative Complications / Q000453:epidemiology*; D011655:Pulmonary Embolism / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D054556:Venous Thromboembolism / Q000453:epidemiology*; D020246:Venous Thrombosis / Q000453:epidemiology; D055815:Young Adult
Deep vein thrombosis; Distraction osteogenesis; Oral and maxillofacial surgery; Orthognathic surgery; Pulmonary embolism; Thrombosis; Venous thromboembolism (VTE)