NO signaling in plant immunity: a tale of messengers.
Nitric oxide (NO) is a free radical gas involved in a myriad of plant physiological processes including immune responses. How NO mediates its biological effects in plant facing microbial pathogen attack is an unresolved question. Insights into the molecular mechanisms by which it propagates signals reveal the contribution of this simple gas in complex signaling pathways shared with reactive oxygen species (ROS) and the second messenger Ca(2+). Understanding of the subtle cross-talks operating between these signals was greatly improved by the recent identification and the functional analysis of proteins regulated through S-nitrosylation, a major NO-dependent post-translational protein modification. Overall, these findings suggest that NO is probably an important component of the mechanism coordinating and regulating Ca(2+) and ROS signaling in plant immunity.
Université de Bourgogne, UMR 1347 Agroécologie, BP 86510, F-21000 Dijon, France; ERL CNRS 6300, BP 86510, 21000 Dijon, France.
Pauline
P
Trapet
INRA, UMR 1347 Agroécologie, BP 86510, F-21000 Dijon, France; ERL CNRS 6300, BP 86510, 21000 Dijon, France.
Anna
A
Kulik
CNRS, UMR 1347 Agroécologie, BP 86510, F-21000 Dijon, France; ERL CNRS 6300, BP 86510, 21000 Dijon, France.
Olivier
O
Lamotte
AgroSup Dijon, UMR 1347 Agroécologie, BP 86510, F-21000 Dijon, France; ERL CNRS 6300, BP 86510, 21000 Dijon, France.
Sylvain
S
Jeandroz
Université de Bourgogne, UMR 1347 Agroécologie, BP 86510, F-21000 Dijon, France; ERL CNRS 6300, BP 86510, 21000 Dijon, France.
Stéphane
S
Bourque
Université de Bourgogne, UMR 1347 Agroécologie, BP 86510, F-21000 Dijon, France; ERL CNRS 6300, BP 86510, 21000 Dijon, France.
Valérie
V
Nicolas-Francès
Université de Bourgogne, UMR 1347 Agroécologie, BP 86510, F-21000 Dijon, France; ERL CNRS 6300, BP 86510, 21000 Dijon, France.
Claire
C
Rosnoblet
Université de Bourgogne, UMR 1347 Agroécologie, BP 86510, F-21000 Dijon, France; ERL CNRS 6300, BP 86510, 21000 Dijon, France.
Angélique
A
Besson-Bard
Université de Bourgogne, UMR 1347 Agroécologie, BP 86510, F-21000 Dijon, France; ERL CNRS 6300, BP 86510, 21000 Dijon, France. Electronic address: wendehen@dijon.inra.fr.
David
D
Wendehenne
D002118:Calcium / Q000378:metabolism; D009569:Nitric Oxide / Q000378:metabolism*; D057865:Plant Immunity; D017382:Reactive Oxygen Species / Q000378:metabolism; D015398:Signal Transduction / Q000276:immunology*
D017382:Reactive Oxygen Species; D009569:Nitric Oxide; D002118:Calcium
Calcium; Calmodulin; Cell death; Nitric oxide; Reactive oxygen species; Signaling