Acute coronary syndrome caused by coronary vasospasms associated with Churg-Strauss syndrome: effects of betamethasone therapy.
A 42-year-old woman with a history of aspirin-induced asthma was admitted with severe chest pain. Emergency coronary angiography revealed coronary artery spasms. The administration of vasodilators did not suppress the anginal symptoms, and the differential white blood cell count continued to show eosinophilia. The patient's symptoms of aspirin-induced asthma, eosinophilia and other allergic states led to the diagnosis of Churg-Strauss syndrome (CSS). After starting betamethasone therapy, the eosinophilia and cardiac symptoms rapidly disappeared. Although coronary vasospasms related to CSS are rare, the present case suggests that a differential white blood cell count should be obtained in patients with refractory coronary vasospasms.
Department of Cardiology, Iwate Prefectural Ninohe Hospital, Japan.
Yuji
Y
Suzuki
Osamu
O
Nishiyama
Toshiaki
T
Sakai
Masanobu
M
Niiyama
Tomonori
T
Itoh
Motoyuki
M
Nakamura
D054058:Acute Coronary Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D000328:Adult; D001623:Betamethasone / Q000008:administration & dosage*; D006328:Cardiac Catheterization; D015267:Churg-Strauss Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D017023:Coronary Angiography; D003329:Coronary Vasospasm / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans
D005938:Glucocorticoids; D001623:Betamethasone