C-H bond functionalization through intramolecular hydride transfer.
Known for over a century, reactions that involve intramolecular hydride-transfer events have experienced a recent resurgence. Undoubtedly responsible for the increased interest in this research area is the realization that hydride shifts represent an attractive avenue for C-H bond functionalization. The redox-neutral nature of these complexity-enhancing transformations makes them ideal for sustainable reaction development. This Review summarizes recent progress in this field while highlighting key historical contributions.
Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, New Brunswick, NJ 08901 (USA) seidel.rutchem.rutgers.edu http://www.seidel-group.com.
Michael C
MC
Haibach
Daniel
D
Seidel
CH functionalization; asymmetric catalysis; cascade reactions; hydride transfer; redox-neutral  reactions