Response surface optimized peroxyoxalate chemiluminescence of octahydro-Schiff base derivative as new luminophor and study of the quenching effect of some cations, amino acids and cholesterol.
We report the first detailed study of the characteristics of an octahydro-Schiff base derivative as a new luminophor in the peroxyoxalate chemiluminescence (POCL) system. The effect of reagents on this new POCL system was investigated. In addition, the response surface methodology was used for evaluating the relative significance of variables in this POCL system, establishing models and determining optimal conditions. The quenching effect of some cations and compounds such as Cu(2+), Fe(3+), Hg(2+), imidazole, histidine and cholesterol on an optimized POCL reaction were studied. The dynamic ranges were up to approximaterly 100 and 175 × 10(-6) M for Cu(2+) and cholesterol respectively. The detection limits were 3.3 × 10(-6) m and 2.58 × 10(-6) m for Cu(2+) and histidine, respectively. In all cases the relative standard deviations were 4-5% (n = 4).
Department of Chemistry, Faculty of Sciences, Payame Noor University, Iran.
Ali
A
Yeganeh Faal
Bahare
B
Jamalyan
Maryam
M
Bordbar
Tavakol Heidary
TH
Shayeste
Masoud
M
Salavati-Niasari
D000596:Amino Acids / Q000737:chemistry; D002412:Cations / Q000032:analysis / Q000737:chemistry; D002784:Cholesterol / Q000032:analysis / Q000737:chemistry*; D003300:Copper / Q000737:chemistry; D006639:Histidine / Q000032:analysis / Q000737:chemistry; D007093:Imidazoles / Q000032:analysis / Q000737:chemistry; D007501:Iron / Q000737:chemistry; D057230:Limit of Detection; D049449:Luminescence; D008163:Luminescent Measurements / Q000379:methods*; D010070:Oxalates / Q000737:chemistry*; D012545:Schiff Bases / Q000737:chemistry; D012680:Sensitivity and Specificity
D000596:Amino Acids; D002412:Cations; D007093:Imidazoles; D010070:Oxalates; D012545:Schiff Bases; D006639:Histidine; C044622:peroxyoxalate; D003300:Copper; D002784:Cholesterol; D007501:Iron
Quenching; Schiff base; peroxyoxalate chemiluminescence; response surface methodology (RSM)