A new triterpenoid from Sapium baccatum (Euphorbiaceae).
A new triterpene, malaytaraxerate (1), and four known compounds, taraxerol (2), taraxerone (3), docosyl isoferulate (4) and docosanoic acid 2',3'-dihydroxypropyl ester (5), were isolated from the acetone extract of Sapium baccatum stem bark. The structures of the isolated compounds were determined using several spectroscopic methods, including UV-Vis, FT-IR, 1D and 2D NMR, and mass spectrometry. Major isolated compounds were assayed for cytotoxicity. The chemotaxonomic significance of this plant was also studied.
a Faculty of Applied Sciences, Universiti Teknologi MARA (UiTM) , 40450 Shah Alam , Selangor , Malaysia.
L M Ramadhan
LM
Al Muqarrabun
Norizan
N
Ahmat
S Ruzaina S
SR
Aris
Norhazana
N
Norizan
Nurdiana
N
Shamsulrijal
Farida Z M
FZ
Yusof
M Nazip
MN
Suratman
M Izwan M
MI
Yusof
Fatimah
F
Salim
D016475:3T3 Cells; D000465:Algorithms; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D019073:HT29 Cells; D006801:Humans; D051379:Mice; D015394:Molecular Structure; D009828:Oleanolic Acid / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D031287:Sapium / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000972:Antineoplastic Agents, Phytogenic; D014315:Triterpenes; C000592868:malaytaraxerate; D009828:Oleanolic Acid; C005802:taraxerol; C009379:taraxerone
Euphorbiaceae; Sapium baccatum; cytotoxicity; malaytaraxerate; triterpenoid