The Ca, Cl, Mg, Na, and P mass fractions in human bone affected by Ewing's sarcoma.
The Ca, Cl, Mg, Na, and P contents and Ca/P, Ca/Mg, Ca/Na, Cl/Ca, and Cl/Na ratios in samples of intact bone, inflamed bone, and Ewing's sarcoma tissue were investigated by neutron activation analysis with high-resolution spectrometry of short-lived radionuclides. In Ewing's sarcoma tissue, the mass fractions of Cl and Na are higher and the mass fractions of Ca and Mg are lower than those of both normal and inflamed bone tissues. It was shown that the levels of Ca and Cl mass fractions and also levels of the Ca/Cl and Cl/Na ratios can be used as an additional test for differential diagnosis between inflamed (or normal) bone and Ewing's sarcoma.
Radionuclide Diagnostics Department, Medical Radiological Research Centre, Koroleva St. 4, Obninsk, 249036, Kaluga Region, Russia, vezai@obninsk.com.
Vladimir
V
Zaichick
Sofia
S
Zaichick
D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000378:metabolism*; D001842:Bone and Bones / Q000378:metabolism*; D002118:Calcium / Q000032:analysis*; D002648:Child; D002712:Chlorides / Q000032:analysis*; D005260:Female; D006801:Humans; D008274:Magnesium / Q000032:analysis*; D008297:Male; D010758:Phosphorus / Q000032:analysis*; D012512:Sarcoma, Ewing / Q000378:metabolism*; D012964:Sodium / Q000032:analysis*; D055815:Young Adult
D002712:Chlorides; D010758:Phosphorus; D012964:Sodium; D008274:Magnesium; D002118:Calcium