[Dyslipidemia in schoolchildren with a history of a high birth weight].
The process of atherosclerosis begins at early ages and is closely related to plasma lipid levels, specifically, an increase in low density lipoprotein (LDL), very low density lipoprotein (VLDL), and a decrease in high density lipoprotein (HDL).


OBJECTIVE
To determine if high birth weight, or macrosomia, is of predictive value for dyslipidemia in school children.


METHODS
A descriptive study with a case control design was conducted on two groups of children; one group of 140 children with a history of macrosomia, and another group of 100 children with normal weight at birth, born between January 1992 and December 1995. The aim was the early identification of atherosclerotic risk factors in school children with high weight at birth. Anthropometric variables and lipid profile were studied (cholesterol, HDL-cholesterol, LDL-cholesterol, VLDL-cholesterol, and triglycerides).


RESULTS
There were significant differences between the mean weights of the two groups. There were no significant statistical differences between the two groups in the cholesterol levels (93.57% normal and 6.43% abnormal in the study group, and 90.00% normal and 10.00% abnormal in the control group), or in the values of HDL cholesterol. LDL cholesterol was abnormal in more children in the control group, and abnormal values of triglycerides were observed in 14.00% of cases in the study group 0.00% in the control group.


CONCLUSIONS
High birth weight is not a predictive factor for hypercholesterolemia or HDL and LDL-cholesterol esters, but is positive for triglycerides in our study.
Facultad de Ciencias Mèdicas Manuel Fajardo, Universidad Médica de La Habana, La Habana, Cuba. Electronic address: nuris@infomed.sld.cu.
Nuris
N
Rodríguez Vargas
Hospital Pedro Borras Astorga, Universidad Mèdica de La Habana, La Habana, Cuba.
Tania P
TP
Martínez Pérez
Facultad de Ciencias Médicas Carlos J. Finlay, Universidad Mèdica de La Habana, La Habana, Cuba.
Rolando
R
Martínez García
Instituto Nacional de Cardiología y Cirugía Cardiovascular, La Habana, Cuba.
Mailin
M
Garriga Reyes
Hospital Clínico Quirúrgico Comandante Manuel Fajardo, Universidad Médica de La Habana, La Habana, Cuba.
Manuel
M
Ortega Soto
Facultad de Ciencias Mèdicas Manuel Fajardo, Universidad Médica de La Habana, La Habana, Cuba.
Teresa
T
Rojas
D001724:Birth Weight; D016022:Case-Control Studies; D002648:Child; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D050171:Dyslipidemias / Q000453:epidemiology*; D005260:Female; D005320:Fetal Macrosomia / Q000453:epidemiology; D006801:Humans; D006937:Hypercholesterolemia / Q000453:epidemiology; D008055:Lipids / Q000097:blood*; D008297:Male; D011237:Predictive Value of Tests; D014280:Triglycerides / Q000097:blood*
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol
Aterosclerosis; Atherosclerosis; Lípidos plasmáticos; Macrosomia; Macrosomía; Plasmatic lipids