Cryptococcal meningitis in a goat--a case report.
BACKGROUND
Cryptococcus spp. are saprophytic and opportunistic fungal pathogens that are known to cause severe disease in immunocompromised animals. In goats there are reports of clinical cryptococcal pneumonia and mastitis but not of meningitis.


METHODS
The following report describes a case of a five year old buck showing severe neurological signs, including paraplegia and strong pain reaction to touch of the hindquarters region. Treatment with antibiotics was unsuccessful and the animal was euthanized for humanitarian reasons. Postmortem examination revealed lumbar meningitis, lung nodules and caseous lymphadenitis lesions. Encapsulated Cryptococcus neoformans were identified from the lungs and meninges, showing that cryptococcal meningitis should be included in the differential diagnosis of goats showing paresis and hyperesthesia. The possibility of concurrent immunosuppression due to Corynebacterium pseudotuberculosis infection is raised.


CONCLUSIONS
Cryptoccocal meningitis should be included in the differential diagnosis list of goat diseases with ataxia and hyperesthesia.
Centro de Investigação Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterinária, University of Lisbon, Alto da Ajuda, Lisbon 1300-477, Portugal. stilwell@fmv.ulisboa.pt.
George
G
Stilwell
Hugo
H
Pissarra
D000818:Animals; D015511:Goat Diseases / Q000469:parasitology* / Q000473:pathology; D006041:Goats; D008297:Male; D016919:Meningitis, Cryptococcal / Q000473:pathology / Q000662:veterinary*