Granulomatous pancreatitis in a patient with acute manifested insulin-dependent diabetes mellitus.
Isolated granulomatous noncaseating pancreatitis is a rare condition exceptionally described in human population. We demonstrate a case of the a 71-years-old female patient suffering from recent diabetes mellitus, generalized atherosclerosis and hypertension who died due to pulmonary embolism and terminal bronchopneumonia. Lipomatosis of pancreatic tissue was observed during the postmortem examination. Histological examination of pancreatic tissue discovered multiple small noncaseating epithelioid cell and giant cell granulomas, partly replacing the islets of Langerhans. To our knowledge, our case represents the first description of noninfectious granulomatous pancreatitis associated with acute manifested insulin-dependent diabetes mellitus.
Department of Pathology, Third Faculty of Medicine, Charles University in Prague, 100 00 Prague 10, Czech Republic.
Václav
V
Mandys
Department of Pathology, Regional Hospital Jihlava, 586 33 Jihlava, Czech Republic.
Michal
M
Kheck
Second Department of Internal Medicine, Third Faculty of Medicine, Charles University in Prague, 100 00 Prague, Czech Republic.
Michal
M
Anděl