Rapidly evolving skin manifestations due to progressive thrombosis in a patient with paroxysmal nocturnal haemoglobinuria resolved with prompt initiation of eculizumab.
Departments of Dermatology, Radboud University Medical Center, 6500HB, Nijmegen, the Netherlands.
E F M
EF
Otters
G
G
Zarafonitis
E J
EJ
Steenbergen
P G M
PG
van der Valk
P
P
Muus
D000328:Adult; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use*; D005076:Exanthema / Q000209:etiology; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006457:Hemoglobinuria, Paroxysmal / Q000150:complications*; D006801:Humans; D017445:Skin Diseases, Vascular / Q000188:drug therapy / Q000209:etiology*; D013927:Thrombosis / Q000188:drug therapy*
D061067:Antibodies, Monoclonal, Humanized; D005343:Fibrinolytic Agents; C481642:eculizumab