A new luteolin triglycoside from Ficus ischnopoda leaves.
A new triglycoside flavone, luteolin-4'-O-α-l-rhamnopyranosyl-(1 → 6)-β-d-glucopyranosyl-(1 → 3)-β-d-glucopyranoside (1) was isolated from the leaves of Ficus ischnopoda, together with five known flavonoids (2-6) and seven known lignans (7-13). Their structures were elucidated on the basis of extensive spectroscopic analysis and comparison with literature data. Compounds 1-13 were reported in this plant for the first time. Compounds 1 and 3-6 exhibited significant anti-HSV-1 activity in vitro.
a Key Laboratory of Standardization of Chinese Medicines, Ministry of Education, Institute of Chinese Materia Medica of Shanghai University of Traditional Chinese Medicine , Cai Lun Road 1200, Zhangjiang , Shanghai 201203 , P.R. China.
Zan-Shan
ZS
Xu
Gui-Xin
GX
Chou
Zheng-Tao
ZT
Wang
D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D030681:Ficus / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018259:Herpesvirus 1, Human / Q000187:drug effects*; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D047311:Luteolin / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry
D000998:Antiviral Agents; D004365:Drugs, Chinese Herbal; D006027:Glycosides; D017705:Lignans; C000592523:luteolin-4'-O-alpha-L-rhamnopyranosyl-(1-6)-beta-D-glucopyranosyl-(1-2)-beta-D-glucopyranoside; D047311:Luteolin
Ficus ischnopoda; Moraceae; anti-HSV-1; luteolin triglycoside