Treatment of HIV in the Central Nervous System.
Central nervous system (CNS) infection is an important part of systemic human immunodeficiency disease (HIV) infection. It is most often asymptomatic, but can sometimes lead to severe neurologic disease, particularly in advanced stages of immunosuppression. CNS HIV infection usually responds well to antiretroviral treatment, but there are concerns that treatment may not always be fully effective in treating or preventing milder CNS disease and that it, under certain circumstances, might be important to consider antiretroviral drug distribution and effects within the CNS.
Department of Infectious Diseases, University of Gothenburg, Gothenburg, Sweden.
Aylin
A
Yilmaz
Department of Infectious Diseases, University of Gothenburg, Gothenburg, Sweden.
Magnus
M
Gisslén
D002493:Central Nervous System Diseases / Q000209:etiology / Q000628:therapy / Q000821:virology; D003072:Cognition Disorders / Q000150:complications / Q000628:therapy / Q000821:virology; D015658:HIV Infections / Q000150:complications* / Q000628:therapy*; D006801:Humans