Cutaneous stigmata associated with insulin resistance and increased cardiovascular risk.
Certain cutaneous conditions have been reported to be associated with diabetes mellitus, insulin resistance, and metabolic syndrome. In this novel review paper, the evidence linking various cutaneous phenomena (e.g. skin tags, acanthosis nigricans, ear lobe creases, and xanthelasma) and metabolic syndrome and cardiovascular disease is examined, and explanations for these associations are proposed.
Clinical Biochemistry and Metabolic Medicine, University Hospital Lewisham and Guy's and St Thomas' Hospital, London, UK.
William H K
WH
Schilling
Martin A
MA
Crook
D000052:Acanthosis Nigricans / Q000150:complications*; D002318:Cardiovascular Diseases / Q000150:complications*; D004431:Ear, External / Q000033:anatomy & histology*; D006801:Humans; D007333:Insulin Resistance; D024821:Metabolic Syndrome / Q000150:complications*; D014973:Xanthomatosis / Q000150:complications*