Specific activity measurement of ⁶⁴Cu: a comparison of methods.
Effective specific activity of (64)Cu (amount of radioactivity per µmol metal) is important in order to determine purity of a particular (64)Cu lot and to assist in optimization of the purification process. Metal impurities can affect effective specific activity and therefore it is important to have a simple method that can measure trace amounts of metals. This work shows that ion chromatography (IC) yields similar results to ICP mass spectrometry for copper, nickel and iron contaminants in (64)Cu production solutions.
Department of Chemistry, Washington University, 1 Brookings Drive, St Louis, MO 63130, USA.
Tara
T
Mastren
University of Missouri Research Reactor, 1513 Research Park Drive, Columbia, MO 65211, USA.
James
J
Guthrie
Department of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110, USA.
Paul
P
Eisenbeis
Department of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110, USA.
Tom
T
Voller
Department of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110, USA.
Efrem
E
Mebrahtu
University of Missouri Research Reactor, 1513 Research Park Drive, Columbia, MO 65211, USA; Department of Chemistry, University of Missouri, 601 S. College Avenue, Columbia, MO 65211, USA.
J David
JD
Robertson
Department of Chemistry, Washington University, 1 Brookings Drive, St Louis, MO 63130, USA; Department of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110, USA. Electronic address: lapis@mir.wustl.edu.
Suzanne E
SE
Lapi
Copper-64; Effective specific activity; Ion chromatography; Trace metal analysis