Primary atypical optic nerve sheath meningioma in a child with restricted diffusion on magnetic resonance imaging.
Optic nerve sheath meningioma is most often discovered in adults and is relatively rare in children. We report a 12-year-old girl with an atypical primary optic nerve meningioma, which demonstrated restricted diffusion on magnetic resonance imaging and high Ki67 labeling index. The patient developed recurrence, despite aggressive surgical resection of primary tumor and local radiation. We are unaware of previous reports documenting this constellation of imaging and histopathologic findings.
Departments of Radiology (SAN), Pathology (MS), and Oncology (JBB), The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
S Ali
SA
Nabavizadeh
Mariarita
M
Santi
Jean B
JB
Belasco
Robert A
RA
Zimmerman
D002648:Child; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000473:pathology*; D008579:Meningioma / Q000473:pathology*; D018317:Nerve Sheath Neoplasms / Q000473:pathology*; D009900:Optic Nerve / Q000473:pathology*