Divergent product selectivity in gold- versus silver-catalyzed reaction of 2-propynyloxy-6-fluoropyridines with arylamines.
A study of the reaction of easily accessible 2-propynyloxy-6-fluoropyridines with arylamines under gold or silver catalysis is described. It has been shown that two types of isomeric oxazolopyridine imine derivatives, which represent unusual heterocyclic motifs, can be selectively obtained in moderate to excellent yields depending on the nature of the metal employed.
Laboratoire de Synthèse Organique, UMR 7652 CNRS/Ecole Polytechnique, Ecole Polytechnique , 91128 Palaiseau, France.
Colombe
C
Gronnier
Pierre Faudot dit
PF
Bel
Guilhem
G
Henrion
Søren
S
Kramer
Fabien
F
Gagosz