Voriconazole-associated soft tissue ossification: an undescribed cause of glenohumeral joint capsulitis.
Voriconazole-related periostitis has been increasingly described in the literature over the last several years as a recognizable disease entity, especially in lung transplant patients. This relationship should be considered when approaching immunosuppressed patients presenting with diffuse bone pain and imaging findings of periostitis. We present a case of voriconazole-associated periostitis, capsular and enthesial ossification and glenuhumeral capsulitis in a patient with a hematologic malignancy. To the authors' knowledge, soft tissue ossification associated with voriconazole has not been described in the radiology literature.
Department of Diagnostic Imaging, Musculoskeletal Radiology, H. Lee Moffitt Cancer Center, Tampa, FL, USA, meera.raghavan@moffitt.org.
Meera
M
Raghavan
Alex
A
Hayes
D000328:Adult; D000935:Antifungal Agents / Q000009:adverse effects; D002062:Bursitis / Q000139:chemically induced* / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009999:Ossification, Heterotopic / Q000139:chemically induced* / Q000175:diagnosis; D010522:Periostitis / Q000139:chemically induced* / Q000175:diagnosis; D012216:Rheumatic Diseases / Q000139:chemically induced* / Q000175:diagnosis; D012785:Shoulder Joint / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D065819:Voriconazole / Q000009:adverse effects*
D000935:Antifungal Agents; D065819:Voriconazole