Pseudohypoparathyroidism type II in a woman with a history of thyroid surgery.
We herein describe the case of a woman with pseudohypoparathyroidism (PHP) type II. She had a history of subtotal thyroidectomy against Graves' disease without levothyroxine supplementation and presented with stiffness, numbness and muscle cramps. Her surgical history suggested the possibility of secondary hypoparathyroidism; however, the serum intact parathyroid hormone level and results of a Ellsworth-Howard test led to the diagnosis of PHP type II. In the present case, making the differential diagnosis was challenging because two distinct disorders, such as PHP and secondary hypoparathyroidism, may exist simultaneously. This case demonstrates the need to consider the possibility of PHP type II in patients exhibiting hypocalcemia.
Department of Diabetes and Endocrinology, Osaka Red Cross Hospital, Japan.
Takaaki
T
Murakami
Takuo
T
Nambu
Yuki
Y
Morimoto
Yuki
Y
Matsuda
Koji
K
Matsuo
Shin
S
Yonemitsu
Seiji
S
Muro
Shogo
S
Oki
D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006111:Graves Disease / Q000601:surgery*; D006801:Humans; D010281:Parathyroid Hormone / Q000097:blood*; D011547:Pseudohypoparathyroidism / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D013965:Thyroidectomy
D010281:Parathyroid Hormone