Initial nucleation site formation due to acoustic droplet vaporization.
Acoustic droplet vaporization (ADV) is the selective vaporization of liquid microdroplets using ultrasound, resulting in gas bubbles. The ADV process has been proposed as a tool in biomedical applications such as gas embolotherapy, drug delivery, and phase-change contrast agents. Using a 7.5 MHz focused transducer, the initial gas nucleus formed in perfluorocarbon microdroplets was directly visualized using ultra-high speed imaging. The experimental results of initial nucleation site location were compared to a 2D axisymmetric linear acoustic model investigating the focal spot of the acoustic wave within the microdroplets. Results suggest a wavelength to droplet diameter dependence on nucleation site formation.
University of Michigan, Ann Arbor, Michigan 48109, USA.
David S
DS
Li
University of Michigan, Ann Arbor, Michigan 48109, USA.
Oliver D
OD
Kripfgans
University of Michigan, Ann Arbor, Michigan 48109, USA.
Mario L
ML
Fabiilli
University of Michigan, Ann Arbor, Michigan 48109, USA.
J
J
Brian Fowlkes
University of Michigan, Ann Arbor, Michigan 48109, USA.
Joseph L
JL
Bull