Eosinophilic granuloma of the mandible: a diagnostic dilemma.
Eosinophilic granuloma (EG) is a rare histiocytic disorder resulting from clonal proliferation of Langerhans cells. It accounts for less than 1% of all osseous neoplasms and has a predilection for involving the axial skeleton. Although suspicion of the disease may arise from clinical features and radiographic demonstration of destructive bone lesions, it is still difficult to make a correct diagnosis without proper pathological evaluation. This is more evident when common differentials mimicking EG, both clinically and radiologically, need to be ruled out. This report describes a case of unifocal EG of the mandible occurring in a 4-year-old boy whose initial presentation led to confusion between osteomyelitis, primary bone tumour and lymphoma. A final diagnosis of EG was established after histopathological examination of the biopsy specimen.
Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, UttarPradesh, India.
Rana K
RK
Sherwani
Kafil
K
Akhtar
Shagufta
S
Qadri
Prasenjit Sen
PS
Ray
D002675:Child, Preschool; D004803:Eosinophilic Granuloma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D011859:Radiography