Evaluation of allelic strength of human TET2 mutations and cooperation between Tet2 knockdown and oncogenic Nras mutation.
McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI, USA.
Yuan-I
YI
Chang
Alisa
A
Damnernsawad
Laura K
LK
Allen
David
D
Yang
Erik A
EA
Ranheim
Ken H
KH
Young
Jingfang
J
Zhang
Guangyao
G
Kong
Jinyong
J
Wang
Yangang
Y
Liu
Hsu-Yuan
HY
Fu
Chii-Shen
CS
Yang
Junjie
J
Guo
Hongjun
H
Song
Jing
J
Zhang
D000483:Alleles; D004252:DNA Mutational Analysis; D004268:DNA-Binding Proteins / Q000235:genetics*; D049308:Dioxygenases; D004843:Epistasis, Genetic; D020558:GTP Phosphohydrolases / Q000235:genetics*; D006801:Humans; D007938:Leukemia / Q000235:genetics / Q000401:mortality; D008565:Membrane Proteins / Q000235:genetics*; D009154:Mutation; D011379:Prognosis; D011518:Proto-Oncogene Proteins / Q000235:genetics*
D004268:DNA-Binding Proteins; D008565:Membrane Proteins; D011518:Proto-Oncogene Proteins; D049308:Dioxygenases; C541081:TET2 protein, human; D020558:GTP Phosphohydrolases; C579846:NRAS protein, human
5hmc; TET2; chronic myelomonocytic leukaemia; oncogenic RAS; whole exome sequencing