Series of five cases of Papulaspora equi keratomycosis.
OBJECTIVE
The aim of this study was to describe a case series of Papulaspora equi keratomycosis, with clinical and laboratory characteristics of an organism that has not been reported from scrapings of corneal ulcers from humans.


METHODS
This is a retrospective chart review of 5 patients whose diagnostic corneal scrapings had grown P. equi on culture between 2008 and 2013. The clinical presentation, diagnostic tests, management, and the outcome of the ulcers are described.


RESULTS
All patients showed characteristic features of fungal corneal ulcers on clinical examination. Only 2 of the 5 patients reported having a history of injury to their eyes. One patient showed surface pigmentation that could mimic a dematiaceous ulcer. All the patients responded to topical antifungal treatment with 5% natamycin or prepared 2% ketoconazole drops.


CONCLUSIONS
Corneal ulcers may be caused by rare organisms, as in our series of patients who had P. equi keratomycosis, a hitherto unreported human pathogen. All the patients responded to treatment with conventional topical antifungal medications.
Departments of *Ophthalmology, and †Microbiology, Christian Medical College, Vellore, India.
Satheesh S T
SS
Selvin
Sanita M G
SM
Korah
Joy S
JS
Michael
Promila M
PM
Raj
Pushpa
P
Jacob
D000287:Administration, Topical; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003320:Corneal Ulcer / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D015821:Eye Infections, Fungal / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D003904:Mitosporic Fungi / Q000187:drug effects / Q000302:isolation & purification*; D009181:Mycoses / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D010866:Natamycin / Q000627:therapeutic use; D009883:Ophthalmic Solutions; D012189:Retrospective Studies
D000935:Antifungal Agents; D009883:Ophthalmic Solutions; D010866:Natamycin