Benefit of a second opinion for lung cancer: no metastasis to the kidney but a synchronous primary renal neoplasm.
BACKGROUND
The finding of a renal mass on imaging is suggestive of metastatic non-small cell lung cancer in the presence of a lung tumor but can also have another origin.


METHODS
We describe the case of a patient diagnosed with stage IV lung cancer based on a renal metastasis. A second opinion including review of histopathological data and additional imaging followed by lung surgery and cryoablation of the kidney lesion revealed two tumors of different origins, non-small cell lung cancer and a renal cell carcinoma.


CONCLUSIONS
The presence of a renal mass diagnosed on a CT scan in a patient with lung cancer is not always synonymous with metastatic disease. Confirmation of diagnosis by tissue sampling is mandatory, especially if a synchronous primary tumor is possible.
Department of Pulmonary Diseases, VU University Medical Center, Amsterdam, The Netherlands.
Marleen J
MJ
Ter Avest
Department of Pulmonary Diseases, VU University Medical Center, Amsterdam, The Netherlands.
Romane M
RM
Schook
Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.
Lyan G
LG
Koudstaal
Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.
Katrien
K
Grünberg
Department of Cardiothoracic Surgery, VU University Medical Center, Amsterdam, The Netherlands.
Marinus A
MA
Paul
Department of Pulmonary Diseases, VU University Medical Center, Amsterdam, The Netherlands.
Egbert F
EF
Smit
Department of Pulmonary Diseases, VU University Medical Center, Amsterdam, The Netherlands.
Pieter E
PE
Postmus
Diagnosis/treatment; Metastatic disease; Non-small cell lung cancer; Renal cell carcinoma; Second opinion; Synchronous primary tumor