Clinical and CT imaging features of mucinous tubular and spindle cell carcinoma.
BACKGROUND
There are relatively few reports focusing on clinical and multi-slice CT (MSCT) imaging findings of mucinous tubular and spindle cell carcinoma (MTSCC). Our study aimed to characterize the clinical and MSCT imaging features of MTSCC.


METHODS
The imaging findings in 17 patients with MTSCC by MSCT were retrospectively studied. MSCT was undertaken to investigate tumor location, size, density, cystic or solid appearance, calcification, capsule sign, enhancement pattern, and retroperitoneal lymph node metastasis.


RESULTS
Tumors (mean diameter, (3.9 ± 1.7) cm) were solitary (17/17), solid (16/17) with cystic components (5/17), had no calcifications (14/17), had a poorly defined margin (14/17), were centered in the medulla (15/17), compressed the renal pelvis (7/17), and neither lymph node nor distant metastasis was found. The attenuation of MTSCC tumors was equal to that of the renal cortex or medulla on unenhanced CT (32.3 ± 2.6, 36.3 ± 4.6, 33.2 ± 3.9, respectively, P > 0.05), while tumor enhancement after administration of a contrast agent was lower than that of normal renal cortex and medulla during all phases (P < 0.05).


CONCLUSIONS
MTSCC tends to be a solitary, isodense mass with poorly defined margin arising from the renal medulla with enhancement less than the cortex and medulla during all phases.
Department of Medical Imaging, Subei People's Hospital, Medical School of Yangzhou University, Yangzhou, Jiangsu 225001, China.
Qingqiang
Q
Zhu
Department of Medical Imaging, Subei People's Hospital, Medical School of Yangzhou University, Yangzhou, Jiangsu 225001, China.
Wenrong
W
Zhu
Department of Radiology, Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, 155 Hanzhong Road, Nanjing, Jiangsu 210029, China. Email: zhq2001us@163.com.
Zhongqiu
Z
Wang
Department of Medical Imaging, Subei People's Hospital, Medical School of Yangzhou University, Yangzhou, Jiangsu 225001, China.
Jingtao
J
Wu
D002288:Adenocarcinoma, Mucinous / Q000175:diagnosis / Q000000981:diagnostic imaging; D000328:Adult; D002277:Carcinoma / Q000175:diagnosis* / Q000000981:diagnostic imaging; D002292:Carcinoma, Renal Cell / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D011859:Radiography