Pharmacologic management of perioperative pulmonary hypertension.
Perioperative pulmonary hypertension can originate from an established disease or acutely develop within the surgical setting. Patients with increased pulmonary vascular resistance are consequently at greater risk for complications. Despite the various specific therapies available, the ideal therapeutic approach in this patient population is not currently clear. This article describes the basic principles of perioperative pulmonary hypertension and reviews the different classes of agents used to promote pulmonary vasodilation in the surgical setting.
*Case Western Reserve University School of Medicine, Cleveland, OH; Departments of †Pulmonary, Allergy, and Critical Care Medicine; and ‡Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, OH; and §Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH.
Julie W
JW
Cheng
Adriano R
AR
Tonelli
Gosta
G
Pettersson
Richard A
RA
Krasuski
D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy / Q000503:physiopathology / Q000628:therapy*; D019990:Perioperative Care; D014665:Vasodilator Agents / Q000627:therapeutic use
D014665:Vasodilator Agents