Bilateral vitreomacular traction resolved with a single intravitreal ocriplasmin injection.
A 74-year-old woman was referred by her ophthalmologist for evaluation of blurred vision in both eyes over the course of several months, presenting with a best corrected visual acuity (BCVA) of 20/150 in the right eye and 20/50 in the left eye. Optical coherence tomography showed vitreomacular traction (VMT) bilaterally with a full-thickness macular hole in the right eye; a single intravitreal injection of 125 μg ocriplasmin was administered in the right eye. One week after the injection, BCVA in the right eye improved to 20/60 with release of VMT, and at 3 weeks bilateral release of VMT was observed.
Randy S
RS
Katz
D000368:Aged; D002199:Capillary Permeability; D005260:Female; D005341:Fibrinolysin / Q000008:administration & dosage / Q000627:therapeutic use*; D005451:Fluorescein Angiography; D006801:Humans; D058449:Intravitreal Injections; D010446:Peptide Fragments / Q000008:administration & dosage / Q000627:therapeutic use*; D012167:Retinal Perforations / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D000267:Tissue Adhesions / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D014822:Vitreous Body / Q000187:drug effects* / Q000473:pathology
D010446:Peptide Fragments; C054561:microplasmin; D005341:Fibrinolysin