Short communication: Monitoring the presence of perfluoroalkyl substances in Italian cow milk.
Perfluoroalkyl substances (PFAS) are fully fluorinated compounds widely used during the last 60 yr in the production of multiple industrial and consumer applications, such as food packaging, nonstick cookware, cleaning agents, and many more. These emerging contaminants have recently become of concern for human health because of their potential negative effects. The risk of exposure to PFAS for humans is mainly related to diet, and the increasing interest in food safety has led the European Commission to call Member States to monitor these contaminants in food matrices. The purpose of the present work was to perform the first monitoring on the presence of perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA), the 2 main and most widely investigated molecules of this family, in cow milk commercially available in Italy. We used an analytical protocol consisting of liquid-liquid extraction followed by 2 purification steps through solid-phase extraction cartridges and injection on an ultra-performance liquid chromatography-tandem mass spectroscopy system. The analysis of 67 samples of different types of cow milk from Italy demonstrated that contamination by PFOS was often present, although at relatively low concentrations (up to 97 ng/L), whereas PFOA was rarely found. On the basis of these results and data reported in the literature on this matrix, milk does not seem to be a major source of PFAS compared with other food categories such as fish and seafood. However, variability among different types of milk must be taken into account, and surveys of milk-derived products would be helpful to better define the risk for consumers.
Laboratorio di Chimica Analitica Bio-Agroalimentare (CABA-Lab), Department of Veterinary Medical Sciences Alma Mater Studiorum, University of Bologna Via Tolara di Sopra 50, 40064 Ozzano dell'Emilia (BO), Italy.
Andrea
A
Barbarossa
Laboratorio di Chimica Analitica Bio-Agroalimentare (CABA-Lab), Department of Veterinary Medical Sciences Alma Mater Studiorum, University of Bologna Via Tolara di Sopra 50, 40064 Ozzano dell'Emilia (BO), Italy.
Teresa
T
Gazzotti
Laboratorio di Chimica Analitica Bio-Agroalimentare (CABA-Lab), Department of Veterinary Medical Sciences Alma Mater Studiorum, University of Bologna Via Tolara di Sopra 50, 40064 Ozzano dell'Emilia (BO), Italy.
Elisa
E
Zironi
Laboratorio di Chimica Analitica Bio-Agroalimentare (CABA-Lab), Department of Veterinary Medical Sciences Alma Mater Studiorum, University of Bologna Via Tolara di Sopra 50, 40064 Ozzano dell'Emilia (BO), Italy.
Andrea
A
Serraino
Laboratorio di Chimica Analitica Bio-Agroalimentare (CABA-Lab), Department of Veterinary Medical Sciences Alma Mater Studiorum, University of Bologna Via Tolara di Sopra 50, 40064 Ozzano dell'Emilia (BO), Italy. Electronic address: giampiero.pagliuca@unibo.it.
Giampiero
G
Pagliuca
D017738:Alkanesulfonic Acids / Q000032:analysis*; D000818:Animals; D002210:Caprylates / Q000032:analysis*; D002417:Cattle; D002853:Chromatography, Liquid; D005260:Female; D005466:Fluorocarbons / Q000032:analysis*; D007558:Italy; D008892:Milk / Q000737:chemistry*; D053719:Tandem Mass Spectrometry
D017738:Alkanesulfonic Acids; D002210:Caprylates; D005466:Fluorocarbons; C023036:perfluorooctanoic acid; C076994:perfluorooctane sulfonic acid
cow milk; perfluoroalkylated substances; perfluorooctane sulfonate (PFOS); perfluorooctanoic acid (PFOA)