I've heard that symptoms of urinary tract infections and bladder cancer are very similar.  My wife has been treated numerous times recently for urinary tract infections.  Could bladder cancer be a possibility?
D003937:Diagnosis, Differential; D006801:Humans; D012008:Recurrence; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis*; D014552:Urinary Tract Infections / Q000175:diagnosis*