Antidromic latency of magnocellular, parvocellular, and koniocellular (Blue-ON) geniculocortical relay cells in marmosets.
We studied the functional connectivity of cells in the lateral geniculate nucleus (LGN) with the primary visual cortex (V1) in anesthetized marmosets (Callithrix jacchus). The LGN sends signals to V1 along parallel visual pathways called parvocellular (P), magnocellular (M), and koniocellular (K). To better understand how these pathways provide inputs to V1, we antidromically activated relay cells in the LGN by electrically stimulating V1 and measuring the conduction latencies of P (n = 7), M (n = 14), and the "Blue-ON" (n = 5) subgroup of K cells (K-BON cells). We found that the antidromic latencies of K-BON cells were similar to those of P cells. We also measured the response latencies to high contrast visual stimuli for a subset of cells. We found the LGN cells that have the shortest latency of response to visual stimulation also have the shortest antidromic latencies. We conclude that Blue color signals are transmitted directly to V1 from the LGN by K-BON cells.
ARC Centre of Excellence in Vision Science,The University of Sydney Eye Hospital Campus,Sydney,New South Wales 2001,Australia.
Soon Keen
SK
Cheong
ARC Centre of Excellence in Vision Science,The University of Sydney Eye Hospital Campus,Sydney,New South Wales 2001,Australia.
Alexander Nicolaas
AN
Johannes Pietersen
D000818:Animals; D001703:Biophysics; D002144:Callithrix; D004558:Electric Stimulation; D004569:Electroencephalography; D005260:Female; D005829:Geniculate Bodies / Q000166:cytology*; D008297:Male; D009474:Neurons / Q000145:classification / Q000502:physiology*; D010775:Photic Stimulation; D011930:Reaction Time / Q000502:physiology*; D014793:Visual Cortex / Q000166:cytology*; D014795:Visual Pathways / Q000502:physiology*