Vitamin B12 deficiency presenting as pancytopenia and retinopathy in a young boy-Helicobacter pylori, a novel causative agent.
Deficiency of vitamin B12 (cobalamin) is a well-known cause of megaloblastic anaemia. It is a reversible cause of bone marrow failure and demyelinating nervous system disorder, hence early detection and prompt treatment of vitamin B12 deficiency is essential. After diagnosing vitamin B12 deficiency, tracking down its root cause is important in individualising the treatment approach. Helicobacter pylorirelated (H. pylori) B12 deficiency presenting as pancytopenia in pediatric age groups has been reported. However, vitamin B12 deficiency presenting as retinopathy in paediatric age groups has been rarely reported in the medical literature. We herein present the case of an adolescent male with pancytopenia and retinopathy, secondary to vitamin B12 deficiency-associated H. pylori infection.
Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India.
Palaniyandi
P
Anitha
Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India.
Rajendraprasad
R
Sasitharan
Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India.
Thalavaisundaram
T
Thambarasi
Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India.
Prabaharan
P
Krithika
Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India.
Madhuvanthi
M
Mohan
Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India.
Paramasivam
P
Venkataraman
Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India.
Saji
S
James
Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India.
Ponnurangam Nagarajan
PN
Vinoth
Helicobacter pylori; Pancytopenia; retinopathy; vitamin B12 deficiency