Bilateral giant coronary aneurysms in a 40-year-old male with Noonan syndrome caused by a KRAS germline mutation.
Department of Molecular and Laboratory Medicine, Mie University Graduate School of Medicine, Tsu, Japan. Electronic address: naokifujimo@clin.medic.mie-u.ac.jp.
Naoki
N
Fujimoto
Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Japan.
Hiroshi
H
Nakajima
Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Japan.
Emiyo
E
Sugiura
Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Japan.
Kaoru
K
Dohi
Department of Thoracic and Cardiovascular Surgery, Mie University Graduate School of Medicine, Tsu, Japan.
Shinji
S
Kanemitsu
Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Japan.
Norikazu
N
Yamada
Department of Medical Genetics, Tohoku University School of Medicine, Sendai, Japan.
Yoko
Y
Aoki
Department of Molecular and Laboratory Medicine, Mie University Graduate School of Medicine, Tsu, Japan.
Kaname
K
Nakatani
Department of Thoracic and Cardiovascular Surgery, Mie University Graduate School of Medicine, Tsu, Japan.
Hideto
H
Shimpo
Department of Molecular and Laboratory Medicine, Mie University Graduate School of Medicine, Tsu, Japan.
Tsutomu
T
Nobori
Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Japan.
Masaaki
M
Ito
D000328:Adult; D003323:Coronary Aneurysm / Q000150:complications / Q000175:diagnosis / Q000235:genetics*; D018095:Germ-Line Mutation / Q000235:genetics*; D006801:Humans; D008297:Male; D009634:Noonan Syndrome / Q000150:complications / Q000175:diagnosis / Q000235:genetics*; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D016283:Proto-Oncogene Proteins p21(ras); D018631:ras Proteins / Q000235:genetics*
C117307:KRAS protein, human; D011518:Proto-Oncogene Proteins; D016283:Proto-Oncogene Proteins p21(ras); D018631:ras Proteins
Coronary aneurysm; KRAS germline mutation; Noonan syndrome