The influence of different implant surfaces on osseointegration in diabetes: a systematic review of the literature.
OBJECTIVE
The aim of this study was to evaluate, through a systematic review of the literature, the effects of different implant surface modifications on osseointegration in diabetic subjects.


METHODS
A search was performed of the PubMed database, using a combination of the following keywords: "Implant surface" OR "Dental implants" AND "Diabetes" OR "Hyperglycemia". Papers published in English between January 1960 and November 2013 were selected. All experimental models were considered in this search, but case reports and in vitro studies were excluded from this review.


RESULTS
The initial search identified 182 articles. After reading the titles and abstracts, 39 articles were selected for full reading. Finally, 4 papers were selected after evaluation of all the papers, and these papers are discussed in this review. Due to the methodological heterogeneity of the selected studies, it was not possible to perform a meta-analysis of the data.


CONCLUSIONS
It can be concluded that although the benefits of surface modifications present in individuals with diabetes have biological plausibility, there is little evidence of the benefits of these modifications.
FUNEC, School of Dentistry Integrated Faculties of Santa Fé do Sul Santa Fé do Sul, SP, Brazil:2 School of Dentistry of Araraquara UNESP-Univ Estadual Paulista Department of Diagnosis and Surgery Araraquara, São Paulo, Brazil - jsampaio@foar.unesp.br.
L A
LA
Fontanari
G J
GJ
Pimentel Lopes De Oliveira
T L
TL
Durigan Basso
E
E
Marcantonio Junior
S R
SR
Perez Orrico
J E
JE
Cezar Sampaio
D015921:Dental Implants; D003920:Diabetes Mellitus / Q000503:physiopathology*; D006801:Humans; D016348:Osseointegration; D013499:Surface Properties
D015921:Dental Implants