Integra® bilayer wound matrix application for complex lower extremity soft tissue reconstruction.
Integra® Bilayer Wound Matrix is composed of cross-linked bovine tendon collagen and glycosaminoglycan with a semi-permeable polysiloxane membrane. This bioengineered tissue provides a matrix for organized cellular migration and proliferation needed to facilitate wound healing while minimizing an inflammatory response. The scaffold provided by Integra® Bilayer Wound Matrix is particularly helpful for building a durable base for coverage of deep soft tissue defects in wounds of all types. We consider the current literature on Integra® Bilayer Wound Matrix and discuss the peri-application management, as well as introduce our treatment algorithms for its use in complex soft tissue reconstruction in the lower extremity.
Center for Wound Healing & Hyperbaric Medicine Department of Plastic Surgery Georgetown University Hospital Washington, District of Columbia.
Paul J
PJ
Kim
Center for Wound Healing & Hyperbaric Medicine Department of Plastic Surgery Georgetown University Hospital Washington, District of Columbia.
Christopher E
CE
Attinger
Center for Wound Healing and Hyperbaric Medicine Department of Plastic Surgery Georgetown University Hospital Washington, District of Columbia.
John S
JS
Steinberg
Center for Wound Healing & Hyperbaric Medicine Department of Plastic Surgery Georgetown University Hospital Washington, District of Columbia.
Karen K
KK
Evans
D001672:Biocompatible Materials / Q000627:therapeutic use*; D002809:Chondroitin Sulfates / Q000627:therapeutic use*; D003094:Collagen / Q000627:therapeutic use*; D006801:Humans; D007869:Leg Injuries / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000295:instrumentation*; D017695:Soft Tissue Injuries / Q000601:surgery*; D014945:Wound Healing
D001672:Biocompatible Materials; C114835:integra artificial skin; D002809:Chondroitin Sulfates; D003094:Collagen