Rare case of phenytoin induced acute generalized exanthematous pustulosis with cerebellar syndrome.
Acute generalized exanthematous pustulosis (AGEP) is a rare drug induced cutaneous hypersensitivity reaction characterized by sudden onset of fever with sterile pustules overlying an erythematous skin occurring all over the body. The offending drugs are usually B-lactams and macrolides. Among anticonvulsants carbamazepine and Phenobarbital are commonly associated with AGEP. Only one case of phenytoin induced AGEP has been reported in literature. We present a rare case of AGEP with cerebellar syndrome occurring after receiving loading dose of phenytoin.
Department of Medicine, Government Medical College and Hospital, Nagpur, India.
Pravin U
PU
Shingade
Department of Skin and V. D., Government Medical College and Hospital, Nagpur, India.
Vaishali
V
Wankhede
Department of Medicine, Government Medical College and Hospital, Nagpur, India.
Pritam S
PS
Kataria
Department of Medicine, Government Medical College and Hospital, Nagpur, India.
Nitin
N
Sonone
Acute generalized exanthematous pustulosis; cerebellar syndrome; phenytoin