SNAP II and SNAPPE II as Predictors of Neonatal Mortality in a Pediatric Intensive Care Unit: Does Postnatal Age Play a Role?
Introduction. In developing countries, a lack of decentralization of perinatal care leads to many high-risk births occurring in facilities that do not have NICU, leading to admission to a PICU. Objective. To assess SNAP II and SNAPPE II as predictors of neonatal death in the PICU. Methodology. A prospective study of newborns divided into 3 groups according to postnatal age: Group 1 (G1), of 0 to 6 days; Group 2 (G2) of 7 to 14 days; and Group 3 (G3), of 15 to 28 days. Variables analyzed were SNAP II, SNAPPE II, perinatal data, and known risk factors for death. The Hosmer-Lemeshow test and the receiver operating characteristics (ROC) curve were used with SPSS 17.0 for statistical analysis. An Alpha error <5% was considered significant. Results. We analyzed 290 newborns, including 192 from G1, 41 from G2, and 57 from G3. Mortality was similar in all 3 groups. Median SNAP II was higher in newborns that died in all 3 groups (P < 0.05). The area under the ROC curve for SNAP II for G1 was 0.78 (CI 95% 0.70-0.86), for G2 0.66 (CI 95% 0.37-0.94), and for G3 0.74 (CI 95% 0.53-0.93). The area under the ROC curve for SNAPPE II for G1 was 0.76 (CI 95% 0.67-0.85), for G2 0.60 (CI 95% 0.30-0.90), and for G3 0.74 (CI 95% 0.52-0.95). Conclusions. SNAP II and SNAPPE II showed moderate discrimination in predicting mortality. The results are not strong enough to establish the correlation between the score and the risk of mortality.
Hospital General Pediátrico "Niños de Acosta Ñú", Avenida de la Victoria and Bacigalupo, Reducto, 2160 San Lorenzo, Paraguay.
Mirta Noemi
0000-0003-1249-3327
MN
Mesquita Ramirez
Hospital General Pediátrico "Niños de Acosta Ñú", Avenida de la Victoria and Bacigalupo, Reducto, 2160 San Lorenzo, Paraguay.
Laura Evangelina
LE
Godoy
Hospital General Pediátrico "Niños de Acosta Ñú", Avenida de la Victoria and Bacigalupo, Reducto, 2160 San Lorenzo, Paraguay.
Elizabeth
E
Alvarez Barrientos