Gold nanoparticle decorated graphene oxide/silica composite stationary phase for high-performance liquid chromatography.
In the initial phase of this study, graphene oxide (GO)/silica was fabricated by assembling GO onto the silica particles, and then gold nanoparticles (GNPs) were used to modify the GO/silica to prepare a novel stationary phase for high-performance liquid chromatography. The new stationary phase could be used in both reversed-phase chromatography and hydrophilic interaction liquid chromatography modes. Good separations of alkylbenzenes, isomerides, amino acids, nucleosides, and nucleobases were achieved in both modes. Compared with the GO/silica phase and GNPs/silica phase, it is found that except for hydrophilicity, large π-electron systems, hydrophobicity, and coordination functions, this new stationary phase also exhibited special separation performance due to the combination of 2D GO with zero-dimensional GNPs.
Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, China.
Xiaojing
X
Liang
Xusheng
X
Wang
Haixia
H
Ren
Shengxiang
S
Jiang
Licheng
L
Wang
Shujuan
S
Liu
D000596:Amino Acids / Q000302:isolation & purification; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation* / Q000379:methods; D056148:Chromatography, Reverse-Phase / Q000295:instrumentation / Q000379:methods; D006108:Graphite / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D057927:Hydrophobic and Hydrophilic Interactions; D053768:Metal Nanoparticles / Q000737:chemistry*; D009705:Nucleosides / Q000302:isolation & purification; D010087:Oxides / Q000737:chemistry; D012822:Silicon Dioxide / Q000737:chemistry
D000596:Amino Acids; D009705:Nucleosides; D010087:Oxides; D012822:Silicon Dioxide; D006108:Graphite
Gold nanoparticles; Graphene oxide; High-performance liquid chromatography; Stationary phases