Tenofovir induced Fanconi syndrome: A rare cause of hypokalemic paralysis.
We report a 55-year-old female who presented to the emergency department with acute onset quadriparesis. She was diagnosed to have acquired immunodeficiency syndrome 7 years ago and was on tenofovir based anti-retroviral therapy for past 10 months. As the patient also had hypophosphatemia, glucosuria and proteinuria Fanconi syndrome (FS) was suspected. She improved dramatically over next 12 h to regain normal power and also her renal functions improved over next few days. Tenofovir induced FS presenting as hypokalemic paralysis is very rare complication and is the first case reported from India.
Department of Neurology, PSG Institute of Medical Science and Research, Coimbatore, India.
E P
EP
Venkatesan
Department of Neurology, PSG Institute of Medical Science and Research, Coimbatore, India.
M B
MB
Pranesh
Department of Neurology, PSG Institute of Medical Science and Research, Coimbatore, India.
G
G
Gnanashanmugam
Department of Nephrology, Kidney Care Centre, Thirunelveli, Tamil Nadu, India.
J
J
Balasubramaniam
Anti-retroviral therapy; Fanconi syndrome; tenofovir