Studies on the T cell receptor (TCR) revision of autoantibody-inducing CD4 T (aiCD4 T) cell.
Our recent studies into the role of autoantibody-inducing CD4 T cells in autoimmune disease have necessitated studies on the mechanism of TCR revision, a phenomenon that has been difficult to approach experimentally. Here we describe a detailed experimental technique to investigate the molecular events involved in TCR revision.
Department of Rheumatology, Kobe University, 4546 Tsurumihara, Beppu, 874-0838, Japan, Shiozawa@beppu.kyushu-u.ac.jp.
Shunichi
S
Shiozawa
Kenichi
K
Uto
D000818:Animals; D001483:Base Sequence; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology* / Q000378:metabolism; D005260:Female; D056426:Genetic Loci; D051379:Mice; D008807:Mice, Inbred BALB C; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction / Q000379:methods; D011948:Receptors, Antigen, T-Cell / Q000235:genetics / Q000276:immunology*
D011948:Receptors, Antigen, T-Cell