Choroidal schwannoma in a 6-month-old girl.
Choroidal schwannomas are exceedingly rare in children, with only 6 cases reported in children younger than 18 years of age and none in those younger than 9 years. We report a 6-month-old infant presenting with a large noncalcified amelanotic mass with secondary glaucoma that mimicked an atypical retinoblastoma, leading to emergent enucleation for therapeutic and diagnostic purposes. Pathology revealed a total retinal detachment, glaucomatous damage, and a large mass arising from the peripapillary posterior choroid with areas of Antoni A pattern and S-100 staining consistent with the diagnosis of an intraocular schwannoma. This is the first intraocular schwannoma described in an infant.
Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
John J
JJ
Chen
Department of Pediatrics, University of Iowa Hospitals and Clinics, Iowa City, Iowa. Electronic address: natalie-kamberos@uiowa.edu.
Natalie L
NL
Kamberos
Department of Pediatrics, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
M Sue
MS
O'Dorisio
Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Nasreen A
NA
Syed
Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Culver
C
Boldt
D002830:Choroid Neoplasms / Q000473:pathology* / Q000601:surgery; D015353:Eye Enucleation; D005260:Female; D005901:Glaucoma / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D033401:Microscopy, Acoustic; D009442:Neurilemmoma / Q000473:pathology* / Q000601:surgery; D012163:Retinal Detachment / Q000175:diagnosis / Q000601:surgery