An in vitro assessment of fluoride uptake by tooth enamel from four different fluoride dentifrices.
OBJECTIVE
The aim of this study was to evaluate fluoride uptake by tooth enamel with four different fluoride dentifrices.


METHODS
Sixty human premolars extracted for orthodontic purpose were selected for the study. The teeth were covered with nail varnish leaving a window of 4 × 4 mm on the enamel surface of the buccal and lingual sides. The teeth were demineralised and were divided into four groups with 15 teeth in each group. The buccal window served as experimental and the lingual as control. The teeth were immersed in toothpaste slurry containing: sodium fluoride (Group A); sodium monofluorophosphate (Group B); stannous fluoride (Group C) and amine fluoride (Group D). The fluoride content in the etched superficial enamel layer in the windows was analysed using a fluoride ion-specific electrode.


RESULTS
Within the parameters of this study, the uptake of fluoride was statistically significant in Group D (p < 0.05). The uptake of fluoride by tooth enamel in an increasing order was Group A < Group B < Group C < Group D.


CONCLUSIONS
The study showed that enamel treated with amine fluoride had the highest fluoride uptake.
Department of Pedodontics and Preventive Dentistry, KLE VK Institute of Dental Sciences, Nehru Nagar, Belgaum, Karnataka, 590010, India, nisarga_vhp@yahoo.com.
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D000588:Amines / Q000493:pharmacokinetics; D002327:Cariostatic Agents / Q000493:pharmacokinetics*; D003743:Dental Enamel / Q000378:metabolism*; D003802:Dentifrices / Q000493:pharmacokinetics*; D005459:Fluorides / Q000493:pharmacokinetics*; D006801:Humans; D066298:In Vitro Techniques; D017736:Ion-Selective Electrodes; D010710:Phosphates / Q000493:pharmacokinetics; D011897:Random Allocation; D012969:Sodium Fluoride / Q000493:pharmacokinetics; D014002:Tin Fluorides / Q000493:pharmacokinetics; D017001:Tooth Demineralization / Q000378:metabolism
D000588:Amines; D002327:Cariostatic Agents; D003802:Dentifrices; D010710:Phosphates; D014002:Tin Fluorides; C012980:fluorophosphate; D012969:Sodium Fluoride; D005459:Fluorides