Applications of computational modeling in cardiac surgery.
Although computational modeling is common in many areas of science and engineering, only recently have advances in experimental techniques and medical imaging allowed this tool to be applied in cardiac surgery. Despite its infancy in cardiac surgery, computational modeling has been useful in calculating the effects of clinical devices and surgical procedures. In this review, we present several examples that demonstrate the capabilities of computational cardiac modeling in cardiac surgery. Specifically, we demonstrate its ability to simulate surgery, predict myofiber stress and pump function, and quantify changes to regional myocardial material properties. In addition, issues that would need to be resolved in order for computational modeling to play a greater role in cardiac surgery are discussed.
Department of Surgery, University of California, San Francisco, California; Department of Bioengineering, University of California, San Francisco, California; Veterans Affairs Medical Center, San Francisco, California.
Lik Chuan
LC
Lee
Martin
M
Genet
Alan B
AB
Dang
Liang
L
Ge
Julius M
JM
Guccione
Mark B
MB
Ratcliffe
D006348:Cardiac Surgical Procedures / Q000379:methods*; D003198:Computer Simulation; D008955:Models, Cardiovascular; D008962:Models, Theoretical; D013903:Thoracic Surgery