Primary leiomyosarcoma of peritoneal cavity.
Leiomyosarcomas of soft tissue are the rare tumors and the retroperitoneum is the most common site involved. We report a case of primary leiomyosarcoma of the peritoneal cavity which clinically presented with suprapubic, freely mobile, nontender mass which measured 10×10 cm in size. Contrast enhanced computed tomography revealed well defined heterogenous hypodense solid cystic mass. The mass was surgically excised out in its entirety. The histopathological examination revealed spindle cells arranged in alternating fascicles having pleomorphic nuclei, indistinct margin and eosinophilic cytoplasm with foci of haemorrhage, necrosis and 5-6 mitosis/HPF. The spindle cells were immunoreactive for smooth muscle actin, desmin and negative for S-100, CD-34 and c-kit. Histopathology and immunohistochemistry were helpful in making the final confirmatory diagnosis. Leiomyosarcomas are aggressive tumors, with poor prognosis and often difficult to treat. The survival rates are lowest among all soft tissue sarcomas.
Department of Pathology, Maulana Azad Medical College , New Delhi, India.
Jyotsna Naresh
JN
Bharti
Department of Pathology, Maulana Azad Medical College , New Delhi, India.
Biswajit
B
Dey
Department of Pathology, Maulana Azad Medical College , New Delhi, India.
Parth
P
Desai
Department of Pathology, Maulana Azad Medical College , New Delhi, India.
Richa
R
Gupta
Department of Pathology, Maulana Azad Medical College , New Delhi, India.
Nita
N
Khurana
Department of Obstetrics and Gynecology, Maulana Azad Medical College , New Delhi, India.
Gauri
G
Gandhi
sarcoma; soft tissue; tumor