Sweetened beverages intake, hyperuricemia and metabolic syndrome: the Mexico City Diabetes Study.
OBJECTIVE. To determine prevalence of hyperuricemia and its relation with intake of sweetened beverages (SB) and metabolic syndrome (MS) in low income urban Mexican population. MATERIALS AND METHODS. A cross-sectional analysis of The Mexico City Diabetes Study, a prospective population-based investigation (1 173 participants) was performed. We used logistic regression, adjusted by pertinent variables. We determined prevalence of hyperuricemia and explored associations of uric acid levels with MS and intake of SB. RESULTS. Prevalence of hyperuricemia was 26.5 and 19.8% in males and females respectively. In an adjusted multivariate model, body mass index, waist circumference, and triglyceride were higher as uric acid quartiles increased (p<0.005-0.001). The odds ratio for MS was 1.48 for 3rd uric acid quartile and 2.03 for 4th quartile. Higher consumption of SB was associated with higher uric acid levels (p<0.001). CONCLUSION. Prevalence of hyperuricemia is high. Potential association with intake of SB, resulting in metabolic alterations should be considered.
Unidad de Investigación en Diabetes y Riesgo Cardiovascular, Instituto Nacional de Salud Pública, México.
Rubén
R
López-Molina
Unidad de Investigación en Diabetes y Riesgo Cardiovascular, Instituto Nacional de Salud Pública, México.
Socorro
S
Parra-Cabrera
Unidad de Investigación en Diabetes y Riesgo Cardiovascular, Instituto Nacional de Salud Pública, México.
Ruy
R
López-Ridaura
María E
ME
González-Villalpando
Department of Medicine, School of Medicine, University of Pisa, Italy.
Ele
E
Ferrannini
Clicerio
C
González-Villalpando
D000368:Aged; D001628:Beverages / Q000706:statistics & numerical data*; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D006801:Humans; D033461:Hyperuricemia / Q000453:epidemiology*; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D013549:Sweetening Agents; D014504:Urban Health
D013549:Sweetening Agents