Interval type-2 fuzzy neural network controller for a multivariable anesthesia system based on a hardware-in-the-loop simulation.
OBJECTIVE
This manuscript describes the use of a hardware-in-the-loop simulation to simulate the control of a multivariable anesthesia system based on an interval type-2 fuzzy neural network (IT2FNN) controller.


METHODS
The IT2FNN controller consists of an interval type-2 fuzzy linguistic process as the antecedent part and an interval neural network as the consequent part. It has been proposed that the IT2FNN controller can be used for the control of a multivariable anesthesia system to minimize the effects of surgical stimulation and to overcome the uncertainty problem introduced by the large inter-individual variability of the patient parameters. The parameters of the IT2FNN controller were trained online using a back-propagation algorithm.


RESULTS
Three experimental cases are presented. All of the experimental results show good performance for the proposed controller over a wide range of patient parameters. Additionally, the results show better performance than the type-1 fuzzy neural network (T1FNN) controller under the effect of surgical stimulation. The response of the proposed controller has a smaller settling time and a smaller overshoot compared with the T1FNN controller and the adaptive interval type-2 fuzzy logic controller (AIT2FLC). The values of the performance indices for the proposed controller are lower than those obtained for the T1FNN controller and the AIT2FLC.


CONCLUSIONS
The IT2FNN controller is superior to the T1FNN controller for the handling of uncertain information due to the structure of type-2 fuzzy logic systems (FLSs), which are able to model and minimize the numerical and linguistic uncertainties associated with the inputs and outputs of the FLSs.
Department of Industrial Electronics and Control Engineering, Faculty of Electronic Engineering, Menofia University, Menouf 32852, Egypt. Electronic address: ahmed_elnagar@menofia.edu.eg.
Ahmad M
AM
El-Nagar
Department of Industrial Electronics and Control Engineering, Faculty of Electronic Engineering, Menofia University, Menouf 32852, Egypt. Electronic address: dralbardini@ieee.org.
Mohammad
M
El-Bardini
D000768:Anesthesia, General; D018685:Anesthetics, Inhalation / Q000493:pharmacokinetics; D001185:Artificial Intelligence; D001794:Blood Pressure; D003198:Computer Simulation; D017143:Fuzzy Logic; D006801:Humans; D007530:Isoflurane / Q000493:pharmacokinetics; D016571:Neural Networks, Computer
D018685:Anesthetics, Inhalation; D007530:Isoflurane
Analgesia; Anesthesia; Back-propagation algorithm; Hardware-in-the-loop; Interval type-2 fuzzy neural network; Muscle relaxation