Maternal serum alpha-fetoprotein levels peak at 19-21 weeks' gestation and subsequently decline in an NPHS1 sequence variant heterozygote; implications for prenatal diagnosis of congenital nephrosis of the Finnish type.
Carolinas Medical Center-Women's Institute, Charlotte, NC, USA.
Teresa B
TB
Brady
Avick G
AG
Mitra
Jessica
J
Hooks
D000328:Adult; D005260:Female; D005820:Genetic Testing; D006579:Heterozygote; D006801:Humans; D008297:Male; D062145:Maternal Serum Screening Tests; D008565:Membrane Proteins / Q000235:genetics*; D009404:Nephrotic Syndrome / Q000097:blood / Q000175:diagnosis* / Q000235:genetics; D011247:Pregnancy; D000509:alpha-Fetoproteins / Q000378:metabolism*
D008565:Membrane Proteins; D000509:alpha-Fetoproteins; C113267:nephrin