Unexpected disappearance of portal cavernoma on long-term anticoagulation.
Idiopathic non-cirrhotic portal hypertension is a rare disease of unknown etiology. Patients with idiopathic non-cirrhotic portal hypertension have an increased risk of developing portal vein thrombosis and this is especially prevalent when HIV is also present. We describe a unique case of a patient with idiopathic non-cirrhotic portal hypertension associated to HIV, who developed acute portal vein thrombosis that despite anticoagulation transformed in portal cavernoma and disappeared completely after five years of follow-up on continuous anticoagulation.
Barcelona Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clinic, Barcelona, Spain; CAPES Foundation, Ministry of Education of Brazil, Brasília DF 70040-020, Brazil.
Gilberto
G
Silva-Junior
Barcelona Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clinic, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (Ciberehd), Spain.
Fanny
F
Turon
Barcelona Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clinic, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (Ciberehd), Spain.
Virginia
V
Hernandez-Gea
Centre de Diagnostic per l'Imatge, Hospital Clinic, Barcelona, Spain.
Anna
A
Darnell
Centre de Diagnostic per l'Imatge, Hospital Clinic, Barcelona, Spain.
Ángeles
Á
García-Criado
Barcelona Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clinic, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (Ciberehd), Spain. Electronic address: jcgarcia@clinic.ub.es.
Juan Carlos
JC
García-Pagán
D000925:Anticoagulants / Q000627:therapeutic use*; D015658:HIV Infections / Q000150:complications; D006392:Hemangioma, Cavernous / Q000188:drug therapy*; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications*; D008103:Liver Cirrhosis / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010198:Pancytopenia / Q000150:complications*; D011169:Portal Vein; D013163:Splenomegaly / Q000150:complications*; D020246:Venous Thrombosis / Q000188:drug therapy*; D000094724:Idiopathic Noncirrhotic Portal Hypertension
D000925:Anticoagulants
Cavernomatosis portal; HIV; Idiopathic non-cirrhotic portal hypertension; Portal vein thrombosis