Computational kinetics of cobalt-catalyzed alkene hydroformylation.
Density functional theory, coupled-cluster theory, and transition state theory are used to build a computational model of the kinetics of phosphine-free cobalt-catalyzed hydroformylation and hydrogenation of alkenes. The model provides very good agreement with experiment, and enables the factors that determine the selectivity and rate of catalysis to be determined. The turnover rate is mainly determined by the alkene coordination step.
School of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS (UK).
Laura E
LE
Rush
Paul G
PG
Pringle
Jeremy N
JN
Harvey
cobalt; density functional calculations; homogeneous catalysis; hydroformylation; reaction kinetics