New strategies and paradigm for drug target discovery: a special focus on infectious diseases tuberculosis, malaria, leishmaniasis, trypanosomiasis and gastritis.
The discovery and exploitation of new drug targets is a key focus for both the pharmaceutical industry and academic research. To provide an insight into trends in the exploitation of new drug targets, we have analysed different methods during the past six decades and advances made in drug target discovery. A special focus remains on different methods used for drug target discovery on infectious diseases such as Tuberculosis, Gastritis, Malaria, Trypanosomiasis and Leishmaniasis. We herewith provide a paradigm that is can be used for drug target discovery in the near future.
Nageswara R R
NR
Neelapu
Ravi C P K
RC
Srimath-Tirumala-Peddinti
Deepthi
D
Nammi
Department of Biochemistry & Bioinformatics, School of Life Sciences, GITAM Institute of Science, GITAM University, Rushikonda Campus, Visakhapatnam -530045, (AP), India. nrneelapu@gmail.com.
Amita C M
AC
Pasupuleti
D000818:Animals; D000977:Antiparasitic Agents / Q000494:pharmacology / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000494:pharmacology / Q000627:therapeutic use; D015195:Drug Design; D055808:Drug Discovery / Q000639:trends*; D005756:Gastritis / Q000188:drug therapy; D006801:Humans; D007896:Leishmaniasis / Q000188:drug therapy; D008288:Malaria / Q000188:drug therapy; D058990:Molecular Targeted Therapy; D014352:Trypanosomiasis / Q000188:drug therapy; D014376:Tuberculosis / Q000188:drug therapy
D000977:Antiparasitic Agents; D000995:Antitubercular Agents