A stepwise approach for the management of poisoning with extracorporeal treatments.
The use of an extracorporeal treatment (ECTR) in a poisoned patient may be life-saving in a limited number of scenarios. The decision-processes surrounding the use of ECTR in poisoning is complex: most nephrologists are not trained to assess a poisoned patient while clinical toxicologists rarely prescribe ECTRs. Deciding on which ECTR is most appropriate for a poison requires a good understanding of the poison's physicochemical and pharmacokinetic properties. Further, a detailed understanding of the capabilities and limitations of the different ECTRs can be useful to select the most appropriate ECTR for a given clinical situation. This manuscript provides a stepwise approach to assess the usefulness of ECTRs in poisoning.
Department of Nephrology, Verdun Hospital, University of Montreal, Montreal, Canada.
Marc
M
Ghannoum
Darren M
DM
Roberts
Robert S
RS
Hoffman
Georges
G
Ouellet
Louise
L
Roy
Brian Scott
BS
Decker
Josée
J
Bouchard
D000818:Animals; D019468:Disease Management; D006801:Humans; D011041:Poisoning / Q000628:therapy*; D006435:Renal Dialysis / Q000379:methods*