Conjugated-polymer-based energy-transfer systems for antimicrobial and anticancer applications.
Conjugated polymers (CPs) attract a lot of attention in sensing, imaging, and biomedical applications because of recent achievements that are highlighted in this Research News article. A brief review of recent progress in the application of CP-based energy-transfer systems in antimicrobial and anticancer treatments is provided. The transfer of excitation energy from CPs to photosensitizers leads to the generation of reactive oxygen species (ROS) that are able to efficiently kill pathogenic microorganisms and cancer cells in the surroundings. Both fluorescence resonance energy transfer (FRET) and bioluminescence energy transfer (BRET) modes are discussed.
Beijing National Laboratory for Molecular Sciences, Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
Huanxiang
H
Yuan
Bing
B
Wang
Fengting
F
Lv
Libing
L
Liu
Shu
S
Wang
D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000737:chemistry*; D004735:Energy Transfer; D017319:Photosensitizing Agents / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*
D000890:Anti-Infective Agents; D000970:Antineoplastic Agents; D017319:Photosensitizing Agents; D011108:Polymers
anticancer; antimicrobial; conjugated polymers; energy transfer; reactive oxygen species