Advances in transcatheter valve therapies.
The surgical treatment for valvular heart disease is well established with excellent long-term outcomes in appropriately selected patients. For patients at elevated risk for surgical intervention, options have traditionally been limited to medical therapy with disappointing results. The advent of transcatheter techniques of valvular repair or replacement has revolutionized treatment options for these patients at significantly elevated risk for surgery. In both the aortic and mitral realms, landmark clinical trials and real-world registries have begun to define the roles of these therapies, and the development of multidisciplinary heart teams have helped optimize patient treatment pathways and outcomes. Transcatheter treatment of aortic stenosis and mitral regurgitation has emerged as an approved option for properly selected patients, and guidelines have evolved to include these therapies. Further procedural refinement, device development, and clinical trials will continue to evolve this field.
Divisions of Cardiology and Cardiothoracic Surgery, Medical University of South Carolina, 25 Courtenay Drive, ART 7031 MSC 592, Charleston, SC, 29425, USA.
Daniel H
DH
Steinberg
Mario
M
Castillo-Sang
Eric R
ER
Powers
D001021:Aortic Valve / Q000503:physiopathology*; D006328:Cardiac Catheterization / Q000295:instrumentation; D006349:Heart Valve Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D008943:Mitral Valve / Q000503:physiopathology*; D011474:Prosthesis Design; D016896:Treatment Outcome