Principles of topical treatment: advancement in gel vehicle technology.
Topical treatment is a pillar of dermatologic practice. The delivery of drug by a topical vehicle is dependent on complex physical chemistry and on how well patients apply the product. The potency of topical agents is not solely dependent on the concentration of active drug in the vehicle. A corticosteroid molecule may have vastly different potency depending on what vehicle is used to deliver it. Similarly, a new gel vehicle is able to deliver considerably more active antifungal than an older vehicle technology and may represent a promising vehicle for other novel formulations. The use of new vehicles can provide more effective means for treating patients with skin disease.
Steven R
SR
Feldman
D000279:Administration, Cutaneous; D005079:Excipients / Q000493:pharmacokinetics; D005782:Gels / Q000493:pharmacokinetics; D006801:Humans; D055118:Medication Adherence; D012871:Skin Diseases / Q000188:drug therapy*
D005079:Excipients; D005782:Gels