Humoral response to calicivirus in captive tigers given a dual-strain vaccine.
The current feline vaccine with a single strain of calicivirus has been used for captive tigers, yet it may not protect against virulent systemic calicivirus infections. A cross-institutional study investigated the humoral response to a new dual-strain, killed-virus calicivirus vaccine for nine captive tigers. The subspecies of these tigers were Amur (Panthera tigris altaica), Bengal (Panthera tigris tigris), and Malayan (Panthera tigris jacksoni). Serum neutralization titers for virulent feline calicivirus strain FCV-DD1 were higher following dual-strain vaccine administration. There were no reports of adverse vaccine reactions. Dual-strain vaccination may afford broadened cross-protection against different calicivirus strains and is desirable to reduce the risk of virulent systemic calicivirus disease in tigers.
Tara M
TM
Harrison
Scott H
SH
Harrison
James G
JG
Sikarskie
Douglas
D
Armstrong
D000818:Animals; D000836:Animals, Zoo; D017250:Caliciviridae Infections / Q000517:prevention & control / Q000662:veterinary*; D017927:Calicivirus, Feline / Q000145:classification* / Q000276:immunology; D005260:Female; D007115:Immunization Schedule; D008297:Male; D046010:Tigers; D014765:Viral Vaccines / Q000008:administration & dosage / Q000276:immunology*
D014765:Viral Vaccines