Management of cutaneous disorders related to inflammatory bowel disease.
Almost one-third of patients with inflammatory bowel disease (IBD) develop skin lesions. Cutaneous disorders associated with IBD may be divided into 5 groups based on the nature of the association: specific manifestations (orofacial and metastatic IBD), reactive disorders (erythema nodosum, pyoderma gangrenosum, pyodermatitis-pyostomatitis vegetans, Sweet's syndrome and cutaneous polyarteritis nodosa), miscellaneous (epidermolysis bullosa acquisita, bullous pemphigoid, linear IgA bullous disease, squamous cell carcinoma-Bowen's disease, hidradenitis suppurativa, secondary amyloidosis and psoriasis), manifestations secondary to malnutrition and malabsorption (zinc, vitamins and iron deficiency), and manifestations secondary to drug therapy (salicylates, immunosupressors, biological agents, antibiotics and steroids). Treatment should be individualized and directed to treating the underlying IBD as well as the specific dermatologic condition. The aim of this review includes the description of clinical manifestations, course, work-up and, most importantly, management of these disorders, providing an assessment of the literature on the topic.
Dermatology Department of the University Clinic Hospital of Valencia (Zaira Pellicer, Vicent Alonso).
Zaira
Z
Pellicer
Inflammatory Bowel Disease Unit of the Gastroenterology and Hepatology Department of the University Clinic Hospital of Valencia (Jesus Manuel Santiago, Rosario Antón, Marta Maia Bosca).
Jesus Manuel
JM
Santiago
Inflammatory Bowel Disease Unit of the Gastroenterology and Hepatology Department of the University Clinic Hospital of Valencia (Jesus Manuel Santiago, Rosario Antón, Marta Maia Bosca).
Alejandro
A
Rodriguez
Dermatology Department of the University Clinic Hospital of Valencia (Zaira Pellicer, Vicent Alonso).
Vicent
V
Alonso
Inflammatory Bowel Disease Unit of the Gastroenterology and Hepatology Department of the University Clinic Hospital of Valencia (Jesus Manuel Santiago, Rosario Antón, Marta Maia Bosca).
Rosario
R
Antón
Inflammatory Bowel Disease Unit of the Gastroenterology and Hepatology Department of the University Clinic Hospital of Valencia (Jesus Manuel Santiago, Rosario Antón, Marta Maia Bosca).
Marta Maia
MM
Bosca
Inflammatory bowel disease; skin disorders; treatment