Disseminated Cutaneous Histoplasmosis, an Initial Manifestation of HIV, Diagnosed with Fine Needle Aspiration Cytology.
Acute progressive disseminated histoplasmosis (PDH) may be the initial manifestation of human immunodeficiency virus (HIV). However, cutaneous involvement is very rare. We present an unusual case of acute PDH with multiple diffuse cutaneous papulonodular lesions predominantly on the face, trunk, and upper extremities, diagnosed initially with fine needle aspiration cytology (FNAC). Subsequent serological tests revealed positivity for antibodies for HIV 1 and 2. The cytomorphological features were further confirmed by biopsy and histochemical stains. FNAC is a rapid, cost-effective tool that may be utilized in the diagnosis of papulonodular forms of PDH and for initiating prompt therapy. We discuss the clinical features, clinical differentials, and treatment of the condition.
Department of Dermatology, North Bengal Medical College, Darjeeling, West Bengal, India.
Sankha
S
Koley
Department of Dermatology, North Bengal Medical College, Darjeeling, West Bengal, India.
Rajesh Kumar
RK
Mandal
Department of Pathology, North Bengal Medical College, Darjeeling, West Bengal, India.
Kalyan
K
Khan
Department of Dermatology, J.N.M.C. Sawangi, Wardha, Maharashtra, India.
Sanjiv
S
Choudhary
Department of Dermatology, North Bengal Medical College, Darjeeling, West Bengal, India.
Sabyasachi
S
Banerjee
Disseminated cutaneous histoplasmosis; fine needle aspiration cytology; human immunodeficiency virus