Oxygen dependency as equivalent to bronchopulmonary dysplasia at different altitudes in newborns ⩽ 1500 g at birth from the SIBEN network.
OBJECTIVE
To compare the incidence of oxygen dependency in SIBEN neonatal units while adjusting for altitude.


METHODS
We reviewed the charts of infants who were ⩽ 1500 g at birth, admitted to six neonatal intensive care units (NICUs) near sea level and in seven NICUs at varying altitudes above sea level from the SIBEN network between 2008 and 2010. We defined bronchopulmonary dysplasia (BPD) as oxygen dependency at 28 days of life and at 36 weeks postmenstrual age.


RESULTS
There were 767 babies in the first group and 318 in the second group. BPD incidence was greater in hospitals at higher altitudes when it was not corrected for barometric pressure. After correction, there was a decrease in the incidence of oxygen dependency at 28 days of life (P<0.0002) and at 36 weeks corrected age. (P<0.0001) CONCLUSION: After correction for higher altitudes, the decrease in oxygen dependency as equivalent to BPD was significant. A proper classification of BPD for higher altitudes is urgently needed.
Instituto Nacional de Perinatología, México, Mexico.
C L A
CL
Fernández
University of Calgary, Calgary, AB, Canada.
C A
CA
Fajardo
Hospital Provincial del Rosario, Rosario, Argentina.
M V
MV
Favareto
Clínica del Country, Bogotá, Colombia.
A
A
Hoyos
Hospital Metropolitano, Quito, Ecuador.
F X
FX
Jijón-Letort
Instituto Nacional de Perinatología, México, Mexico.
M S
MS
Carrera
Instituto Nacional de Perinatología, México, Mexico.
M E
ME
Yllescas
Instituto Nacional de Perinatología, México, Mexico.
M S
MS
Romero
D000531:Altitude; D001997:Bronchopulmonary Dysplasia / Q000453:epidemiology* / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight; D007363:Intensive Care Units, Neonatal; D010100:Oxygen / Q000097:blood*; D012121:Respiration, Artificial; D012189:Retrospective Studies; D012307:Risk Factors
D010100:Oxygen