Sclerosing Angiomatoid Nodular Transformation of the Spleen: A New Entity or a New Name?
Sclerosing angiomatoid nodular transformation of the splenic red pulp has been described quite recently; many of the lesions previously diagnosed as splenic exuberant granulation tissue, multinodular hemangioma, and inflammatory pseudotumor could actually belong to this category. The lesion has been well reported intermittently in the past, but new cases with still newer associations keep appearing from time to time. There are no known risk factors and no inciting triggers have been proven. We report two such cases- one of which has extensive extramedullary haematopoiesis; a feature that has never been reported earlier. Clinico-morphological and radiological features along with pathogenesis are discussed in detail.
Department of Pathology, Nizam's Institute of Medical Sciences, HYDERABAD, INDIA.
Meetu
M
Agrawal
Shantveer G
SG
Uppin
Srinivas
S
Bh
Megha
M
Suppin
Bheerappa
B
N
Sundaram
S
Challa
D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D002648:Child; D005260:Female; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D013160:Splenic Neoplasms / Q000473:pathology*; D019043:Vascular Neoplasms / Q000473:pathology*
D014408:Biomarkers, Tumor