Fun and games in Berkeley: the early years (1956-2013).
Life at Berkeley for the past 57 years involved research on the thermodynamics, kinetics, and spectroscopic properties of RNA to better understand its structures, interactions, and functions. We (myself and all the graduate students and postdocs who shared in the fun) began with dinucleoside phosphates and slowly worked our way up to megadalton-sized RNA molecular motors. We used UV absorption, circular dichroism, circular intensity differential scattering, fluorescence, NMR, and single-molecule methods. We learned a lot and had fun doing it.
Chemistry Department, University of California, Berkeley, California 94720; email: intinoco@lbl.gov.
Ignacio
I
Tinoco
D002140:California; D002942:Circular Dichroism; D049673:History, 20th Century; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D012313:RNA / Q000737:chemistry*; D013816:Thermodynamics
D012313:RNA
NMR; RNA structure; circular dichroism; laser tweezers; ribosome; translation