Effect of exposure and withdrawal of 900-MHz-electromagnetic waves on brain, kidney and liver oxidative stress and some biochemical parameters in male rats.
Increasing use of mobile phones in daily life with increasing adverse effects of electromagnetic radiation (EMR), emitted from mobile on some physiological processes, cause many concerns about their effects on human health. Therefore, this work was designed to study the effects of exposure to mobile phone emits 900-MHz EMR on the brain, liver and kidney of male albino rats. Thirty male adult rats were randomly divided into four groups (10 each) as follows: control group (rats without exposure to EMR), exposure group (exposed to 900-MHz EMR for 1 h/d for 60 d) and withdrawal group (exposed to 900-MHz electromagnetic wave for 1 h/d for 60 d then left for 30 d without exposure). EMR emitted from mobile phone led to a significant increase in malondialdehyde (MDA) levels and significant decrease total antioxidant capacity (TAC) levels in brain, liver and kidneys tissues. The sera activity of alanine transaminase (ALT), aspartate aminotransferase (AST), urea, creatinine and corticosterone were significantly increased (p < 0.05), while serum catecholamines were insignificantly higher in the exposed rats. These alterations were corrected by withdrawal. In conclusion, electromagnetic field emitting from mobile phone might produce impairments in some biochemicals changes and oxidative stress in brain, liver and renal tissue of albino rats. These alterations were corrected by withdrawal.
a Department of Physiology, Faculty of Medicine , Minia University , Minia , Egypt.
Merhan Mamdouh
MM
Ragy
D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D000975:Antioxidants / Q000737:chemistry; D001219:Aspartate Aminotransferases / Q000097:blood; D001921:Brain / Q000528:radiation effects*; D040421:Cell Phone; D003345:Corticosterone / Q000097:blood; D003404:Creatinine / Q000097:blood; D004574:Electromagnetic Fields; D060733:Electromagnetic Radiation; D007668:Kidney / Q000528:radiation effects*; D008099:Liver / Q000528:radiation effects*; D008297:Male; D008315:Malondialdehyde / Q000737:chemistry; D018384:Oxidative Stress; D051381:Rats; D017207:Rats, Sprague-Dawley; D014508:Urea / Q000097:blood
D000975:Antioxidants; D008315:Malondialdehyde; D014508:Urea; D003404:Creatinine; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D003345:Corticosterone
Brain and renal and liver function; electromagnetic radiation; total antioxidant capacity