First case of bilateral, synchronous anaplastic variant of spermatocytic seminoma treated with radical orchifunicolectomy as single approach: case report and review of the literature.
Spermatocytic Seminoma (SS) is less common than the Classic variant, as its incidence ranges between 1.3% and 2.3% of all seminomas. Generally SS is diagnosed in men older than 50 years. The Anaplastic variant of Spermatocytic Seminoma is characterized by an earlier onset when compared to SS, but a benign behavior in spite of its histological patterns similar to Classic Seminoma. We reported the first case of bilateral, largest and synchronous Anaplastic Spermatocytic Seminoma, in a patient treated with radical orchifunicolectomy alone and with long-term follow-up. The currently available data show that Anaplastic SS reveals a clinically benign behavior, and no distant metastases have been reported so far. A close surveillance after surgery could be considered a valid option in the management of this rare testicular neoplasm.
Department of Urology, Azienda Ospedaliero-Universitaria Policlinico S.Orsola-Malpighi, Bologna. dr.giorgio.gentile@gmail.com.
Giorgio
G
Gentile
Francesca
F
Giunchi
Riccardo
R
Schiavina
Alessandro
A
Franceschelli
Marco
M
Borghesi
Ziv
Z
Zukerman
Matteo
M
Cevenini
Valerio
V
Vagnoni
Daniele
D
Romagnoli
Fulvio
F
Colombo
Giuseppe
G
Martorana
Eugenio
E
Brunocilla
D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000473:pathology / Q000601:surgery*; D009919:Orchiectomy / Q000379:methods; D018239:Seminoma / Q000473:pathology / Q000601:surgery*; D013090:Spermatocytes / Q000473:pathology; D013736:Testicular Neoplasms / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome