Supercritical fluid chromatography as a tool for enantioselective separation; a review.
Supercritical fluid chromatography (SFC) has become popular in the field of enantioselective separations. Many works have been reported during the last years. This review covers the period from 2000 till August 2013. The article is divided into three main chapters. The first one comprises a basic introduction to SFC. The authors provide a brief explanation of general principles and possibilities of this method. The advantages and drawbacks are also listed. Next part deals with chiral separation systems available in SFC, namely with the commonly used chiral stationary phases. Properties and interaction possibilities of the chiral separation systems are described. Recent theoretical papers are emphasized in this chapter. The last part of the paper gives an overview of applications of enantioselective SFC in analytical chemistry, in both analytical and preparative scales. Separation systems and conditions are summed up in tables so that they provide a helpful tool for analysts who search for a particular method of analysis.
Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University in Prague, Prague, Czech Republic. Electronic address: kalikova@natur.cuni.cz.
Květa
K
Kalíková
Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University in Prague, Prague, Czech Republic. Electronic address: tereza.slechtova@natur.cuni.cz.
Tereza
T
Slechtová
Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University in Prague, Prague, Czech Republic. Electronic address: vozka@natur.cuni.cz.
Jiří
J
Vozka
Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University in Prague, Prague, Czech Republic. Electronic address: tesarove@natur.cuni.cz.
Eva
E
Tesařová
D025924:Chromatography, Supercritical Fluid / Q000295:instrumentation / Q000379:methods*; D004867:Equipment Design; D006020:Glycopeptides / Q000737:chemistry; D054802:Molecular Imprinting; D011108:Polymers / Q000737:chemistry; D011134:Polysaccharides / Q000737:chemistry; D013237:Stereoisomerism
D006020:Glycopeptides; D011108:Polymers; D011134:Polysaccharides
Chiral stationary phase; Enantiomers; Enantioselective separation; Review; Supercritical fluid chromatography