Early infection of hip joint prosthesis by Clostridium difficile in an HIV-1 infected patient.
Anaerobes are less frequently described as causative pathogen of prosthetic joint infection (PJI). We report the first case of early PJI after hip arthroplasty due to Clostridium difficile in a diabetic and HIV-1 infected patient with bacteremia. Our patient was successfully treated through surgical debridement and prosthesis retention combined with targeted antibiotic therapy.
Microbiology Department, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, 10 Av Hippocrate, 1200 Brussels, Belgium. Electronic address: laeti.brassinne@skynet.be.
L
L
Brassinne
Microbiology Department, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, 10 Av Hippocrate, 1200 Brussels, Belgium. Electronic address: hector.rodriguez@uclouvain.be.
H
H
Rodriguez-Villalobos
Internal Medicine and Infectious Diseases Department, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, 10 Av Hippocrate, 1200 Brussels, Belgium. Electronic address: jonckheeresy@gmail.com.
S
S
Jonckheere
Orthopaedic Department, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, 10 Av Hippocrate, 1200 Brussels, Belgium. Electronic address: jean-emile.dubuc@uclouvain.be.
J E
JE
Dubuc
Internal Medicine and Infectious Diseases Department, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, 10 Av Hippocrate, 1200 Brussels, Belgium. Electronic address: jean.yombi@uclouvain.be.
J C
JC
Yombi
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects; D016470:Bacteremia / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy; D016360:Clostridioides difficile / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D003646:Debridement; D048909:Diabetes Complications; D015658:HIV Infections / Q000150:complications*; D015497:HIV-1 / Q000302:isolation & purification; D006621:Hip Joint / Q000382:microbiology* / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy
D000900:Anti-Bacterial Agents
Anaerobes prosthetic infection; Clostridium difficile; HIV; Immunocompromised infection; Prosthetic joint infection