In melanoma, Hippo signaling is affected by copy number alterations and YAP1 overexpression impairs patient survival.
Department of Dermatology, University of Tübingen, Tübingen, Germany.
Moritz
M
Menzel
Diana
D
Meckbach
Benjamin
B
Weide
Nora C
NC
Toussaint
Karin
K
Schilbach
Seema
S
Noor
Thomas
T
Eigentler
Kristian
K
Ikenberg
Christian
C
Busch
Leticia
L
Quintanilla-Martinez
Ursula
U
Kohlhofer
Antonia
A
Göke
Friederike
F
Göke
Rupert
R
Handgretinger
Christian
C
Ottmann
Boris C
BC
Bastian
Claus
C
Garbe
Martin
M
Röcken
Sven
S
Perner
Oliver
O
Kohlbacher
Jürgen
J
Bauer
D048868:Adaptor Proteins, Signal Transducing / Q000096:biosynthesis / Q000235:genetics; D018572:Disease-Free Survival; D005260:Female; D018628:Gene Dosage; D015972:Gene Expression Regulation, Neoplastic; D000090683:Hippo Signaling Pathway; D006801:Humans; D008297:Male; D008545:Melanoma / Q000235:genetics / Q000378:metabolism / Q000401:mortality; D009363:Neoplasm Proteins / Q000096:biosynthesis / Q000235:genetics; D010750:Phosphoproteins / Q000096:biosynthesis / Q000235:genetics; D017346:Protein Serine-Threonine Kinases / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction / Q000235:genetics*; D015996:Survival Rate; D014157:Transcription Factors; D000091102:YAP-Signaling Proteins
D048868:Adaptor Proteins, Signal Transducing; D009363:Neoplasm Proteins; D010750:Phosphoproteins; D014157:Transcription Factors; D000091102:YAP-Signaling Proteins; C088374:YAP1 protein, human; D017346:Protein Serine-Threonine Kinases