Capturing [¹¹C]CO₂ for use in aqueous applications.
We present a simple method for trapping [(11)C]CO2 gas and releasing it into a buffered solution using an ion-exchange cartridge. Sodium hydroxide cartridges captured >99% of [(11)C]CO2 following NaOH activation. A sodium bicarbonate solution eluted >99% of trapped radioactivity. Trapping [(11)C]CO2 directly in small volumes of several solutions was less effective than cartridge methods. The recommended methods allow for fast and simple production of highly concentrated carbon-11 containing aqueous solutions for use in filling phantoms, calibrating detectors, or (bio)geochemical experiments.
Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA. Electronic address: ntvandehey@lbl.gov.
Nicholas T
NT
Vandehey
Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA. Electronic address: jponeil@lbl.gov.
James P
JP
O'Neil
Carbon capture; Carbon-11; Ion exchange; Positron emission tomography; Radiochemistry; [(11)C]CO(2)