Iridium-catalyzed C-H amination with anilines at room temperature: compatibility of iridacycles with external oxidants.
Described herein is the development of an iridium-catalyzed direct C-H amination of benzamides with anilines at room temperature, representing a unique example of an Ir catalyst system that is compatible with external oxidants. Mechanistic details, such as the isolation and characterization of key iridacycle intermediates, are also discussed.
Center for Catalytic Hydrocarbon Functionalization, Institute of Basic Science (IBS) , Daejeon 305-701, Korea.
Hyunwoo
H
Kim
Kwangmin
K
Shin
Sukbok
S
Chang