Asymptomatic bladder metastasis from breast cancer.
Introduction. Breast cancer is the most common nondermatologic cancer in women. Common metastatic sites include lymph nodes, lung, liver, and bone. Metastases to the bladder are extremely rare, with all reported cases presenting with urinary symptoms. Case Report. Herein, we report the first case of completely asymptomatic bladder metastasis from breast cancer, occasionally revealed, 98 months after the initial diagnosis of lobular breast carcinoma, by a follow-up computed tomography scanning showing thickening of left bladder wall and grade II left hydronephrosis. A positive staining for estrogen and progesterone receptors was confirmed by immunohistochemistry. Discussion. The reported case confirms that bladder metastases from breast cancer tend to occur late after the diagnosis of the primary tumor and, for the first time, points out they can be asymptomatic. Conclusion. Such data support the need for careful follow-up and early intervention whenever such clinical situation is suspected.
Department of Urology and Renal Transplantation, University of Foggia, Viale Luigi Pinto 1, 71121 Foggia, Italy.
Luigi
0000-0002-1126-5368
L
Cormio
Department of Pathology, University of Foggia, Viale Luigi Pinto 1, 71121 Foggia, Italy.
Francesca
0000-0001-7459-3521
F
Sanguedolce
Department of Urology and Renal Transplantation, University of Foggia, Viale Luigi Pinto 1, 71121 Foggia, Italy.
Giuseppe
G
Di Fino
Department of Urology and Renal Transplantation, University of Foggia, Viale Luigi Pinto 1, 71121 Foggia, Italy.
Paolo
P
Massenio
Department of Urology and Renal Transplantation, University of Foggia, Viale Luigi Pinto 1, 71121 Foggia, Italy.
Giuseppe
0000-0003-0234-992X
G
Liuzzi
Department of Urology and Renal Transplantation, University of Foggia, Viale Luigi Pinto 1, 71121 Foggia, Italy.
Nicola
N
Ruocco
Department of Pathology, University of Foggia, Viale Luigi Pinto 1, 71121 Foggia, Italy.
Pantaleo
P
Bufo
Department of Urology and Renal Transplantation, University of Foggia, Viale Luigi Pinto 1, 71121 Foggia, Italy.
Giuseppe
G
Carrieri