Sulfuryl chloride as an efficient initiator for the metal-free aerobic cross-dehydrogenative coupling reaction of tertiary amines.
A metal-free cross-dehydrogenative (CDC) reaction of tertiary amines was developed using a catalytic amount of sulfuryl chloride (SO2Cl2) under mild aerobic conditions. On the basis of the nature of SO2Cl2, it was assumed that the reagent acts as a radical initiator to induce the metal-free CDC reaction via a radical-initiated autoxidation mechanism.
Department of Chemistry, School of Science, The University of Tokyo , Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Arata
A
Tanoue
Woo-Jin
WJ
Yoo
Shū
S
Kobayashi