3D bioelectronic interface: capturing circulating tumor cells onto conducting polymer-based micro/nanorod arrays with chemical and topographical control.
The three-dimensional (3D) poly(3,4-ethylenedioxythiophene) (PEDOT)-based bioelectronic interfaces (BEIs) with diverse dimensional micro/nanorod array structures, varied surface chemical pro-perties, high electrical conductivity, reversible chemical redox switching, and high optical transparency are used for capturing circulating tumor cells (CTCs). Such 3D PEDOT-based BEIs can function as an efficient clinical diagonstic and therapeutic platform.
Department of Materials Engineering, Ming Chi University of Technology, 84 Gunjuan Road, Taishan, New Taipei City, 24301, Taiwan; Research Center for Applied Sciences, Academia Sinica, Taipei, 11529, Taiwan.
Yu-Sheng
YS
Hsiao
Shyh-Chyang
SC
Luo
Shuang
S
Hou
Bo
B
Zhu
Jun
J
Sekine
Chiung-Wen
CW
Kuo
Di-Yen
DY
Chueh
Hsiao-Hua
HH
Yu
Hsian-Rong
HR
Tseng
Peilin
P
Chen
D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000737:chemistry*; D045744:Cell Line, Tumor; D002469:Cell Separation / Q000295:instrumentation*; D003217:Conductometry / Q000295:instrumentation*; D004553:Electric Conductivity; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D008904:Miniaturization; D043942:Nanotubes / Q000737:chemistry* / Q000648:ultrastructure; D009360:Neoplastic Cells, Circulating / Q000473:pathology*; D011108:Polymers / Q000737:chemistry*; D013499:Surface Properties; D046888:Tissue Array Analysis
D019086:Bridged Bicyclo Compounds, Heterocyclic; D011108:Polymers; C121383:poly(3,4-ethylene dioxythiophene)
bioelectronic interface; cancer diagnosis; circulating tumor cells; nanostructured materials; poly(3,4-ethylenedioxythiophene) (PEDOT)