A new alkaloid glycoside from the rhizomes of Aristolochia fordiana.
A new alkaloid glycoside named fordianoside (1), together with three known compounds arabinothalictoside (2), 6-O-p-coumaroyl-β-fructofuranosyl-(2 → 1)-α-d-glucopyranoside (3) and 4-[formyl-5-(hydroxymethyl)-1H-pyrrol-1-yl] butanoic acid (4), was isolated from the rhizomes of Aristolochia fordiana. The structure of 1 was established as (1S)-1,2,3,4-tetrahydro-7-hydroxy-1-[(4-hydroxybenzyl) methyl]-2,2-dimethyl-8-O-isoquinolinyl β-d-glucopyranoside by using chemical and spectroscopic methods including HR-ESI-MS, 1D and 2D NMR.
a State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry , China Pharmaceutical University , 24 Tong Jia Xiang, Nanjing 210009 , People's Republic of China.
Zhongbo
Z
Zhou
Jianguang
J
Luo
Ke
K
Pan
Lingyi
L
Kong
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D030022:Aristolochia / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D027343:Rhizome / Q000737:chemistry*; D013237:Stereoisomerism
D000470:Alkaloids; D004365:Drugs, Chinese Herbal; D005960:Glucosides; D006027:Glycosides; C102250:arabinothalictoside; C000592643:fordianoside
Aristolochia fordiana; Aristolochiaceae; alkaloid glycoside