Toward unraveling heme regulation.
In this issue of Blood, Garcia-Santos et al advance the field of heme regulation, a highly complex process involving iron and globin metabolism. They focus on a key enzyme involved in heme catabolism, heme oxygenase 1 (HO-1), which, ironically, has been poorly investigated in erythroid cells, the largest pool of heme-containing cells.
HÔPITAL UNIVERSITAIRE NECKER-ENFANTS MALADES;
Valentine
V
Brousse
Wassim
W
El Nemer
D000818:Animals; D041905:Erythroid Cells / Q000378:metabolism*; D006418:Heme / Q000378:metabolism*; D051547:Heme Oxygenase-1 / Q000235:genetics*
D006418:Heme; D051547:Heme Oxygenase-1