Trapping of azidocarbenium ion: a unique route for azide synthesis.
For the first time, a sensitive azidocarbenium ion intermediate has been trapped with various nucleophiles to provide azides in excellent chemoselectivity. This provides a novel approach for the chemoselective synthesis of primary and secondary benzyl azides from aldehydes in a one-pot reaction. Enantioselective nucleophilic addition to the azidocarbenium ion has also been initiated.
Department of Chemistry, Indian Institute of Science Education and Research Bhopal , Indore By-pass Road, Bhauri, Bhopal 462066, India.
Suman
S
Pramanik
Prasanta
P
Ghorai