[Incidental intraplacental gestational choriocarcinoma on a full-term placenta].
Of all the gestational trophoblastic tumors, the gestational choriocarcinomas have the worst prognosis and the most uncommon. We report a case diagnosed on a full-term placenta, discovered incidentally. The patient, gravida 2, para 1, delivered a hypotrophic infant at 38 weeks gestation. The placenta was examined in the laboratory to perform anatomo-pathological examination in order to explain the growth retardation. This study revealed the presence of an intraplacental choriocarcinoma. Disease staging was negative for both mother and child, and beta-HCG levels remained at zero. These two factors are rather good prognosis for choriocarcinoma. With this observation, we highlight the added-value of placental examination, which seems essential for any fetal pathology, pathological pregnancy and intrapartum complications. Anatomo-pathological examination must be meticulous and systematized in order to not overlook an intraplacental tumor.
Unité de pathologie fœtoplacentaire, université Bordeaux-Segalen, 146, rue Léo-Saignat, 33076 Bordeaux cedex, France. Electronic address: fanny.sauvestre@gmail.com.
Fanny
F
Sauvestre
Unité de pathologie fœtoplacentaire, université Bordeaux-Segalen, 146, rue Léo-Saignat, 33076 Bordeaux cedex, France.
Dominique
D
Carles
Service d'anatomie et cytologie pathologiques, hôpital Robert-Boulin, 112, rue de la Marne, 33505 Libourne cedex, France.
Martie
M
Faure
Service d'anatomie et cytologie pathologiques, hôpital Robert-Boulin, 112, rue de la Marne, 33505 Libourne cedex, France.
Floriane
F
Taillat
Service de gynécologie, hôpital Robert-Boulin, 112, rue de la Marne, 33505 Libourne cedex, France.
Fanny
F
Le Boulanger
Service d'anatomie et cytologie pathologiques, CHU Pellegrin, place Amélie-Raba-Léon, 33076 Bordeaux cedex, France.
Claire
C
Castain
Unité de pathologie fœtoplacentaire, université Bordeaux-Segalen, 146, rue Léo-Saignat, 33076 Bordeaux cedex, France.
Gwenaëlle
G
André
Unité de pathologie fœtoplacentaire, université Bordeaux-Segalen, 146, rue Léo-Saignat, 33076 Bordeaux cedex, France.
Fanny
F
Pelluard
D000328:Adult; D002822:Choriocarcinoma / Q000473:pathology*; D005260:Female; D006801:Humans; D033162:Incidental Findings; D010922:Placenta Diseases / Q000473:pathology*; D011247:Pregnancy; D047929:Term Birth
Choriocarcinome in situ; Choriocarcinome intra-placentaire gestationnel; In situ choriocarcinoma; Intraplacental gestational choriocarcinoma; Placenta; Trophoblastic tumor; Tumeur trophoblastique