Dehydroepiandrosterone sulfate levels in Turkish obese patients.
OBJECTIVE
Obesity is well known to be linked to higher morbidity and mortality. Elevated plasma levels of free dehydroepiandrosterone (DHEA) are associated with reduced obesity and more limited accumulation of abdominal body fat. In contrast, the relationship between the DHEA sulfate ester (DHEAS) and adiposity is inconsistent and contradictory.


METHODS
The aim of this study was to compare DHEAS levels in obese Turkish individuals, 37 men and 246 women. A variety of fatness, hormone, and blood parameters were measured.


RESULTS
Statistically significant differences were found between male and female individuals with respect to weight, waist circumference, fat %, insulin, and DHEAS levels.


CONCLUSIONS
We found that in the Turkish population, while a correlation between obesity parameters and DHEAS levels exists in both female and male individuals, DHEAS levels are significantly higher in obese male individuals than in obese female individuals.
Department of Endocrinology and Metabolism, Burdur State Hospital, Yeni Mahalle, Burdur, 15030, Turkey, topsakals@hotmail.com.
Senay
S
Topsakal
Fulya
F
Akin
Emrah
E
Yerlikaya
Tuba
T
Erurker
Hilmi
H
Dogu
D000293:Adolescent; D000328:Adult; D000368:Aged; D001823:Body Composition; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D019314:Dehydroepiandrosterone Sulfate / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood*; D014421:Turkey; D055815:Young Adult
D019314:Dehydroepiandrosterone Sulfate