[Sclerotization of orbital lymphangioma with OK-432].
Orbital lymphangiomas are mostly congenital, apparent vascular space-occupying lesions, which can lead to disfiguring swelling of the periorbital soft tissues, ocular motility disorders, optic nerve compression and keratopathy. The treatment is challenging because the disease is principally incurable. Lymphangiomatous tissue can be surgically partially reduced or treated by intralesional injection of various sclerosants. In this review we report the successful use of OK-432 for destruction of a macrocystic orbital lymphangioma.
Klinik für Augenheilkunde, Universitätsklinikum Freiburg, 79106, Freiburg, Deutschland, wolf.lagreze@uniklinik-freiburg.de.
W
W
Lagrèze
M
M
Metzger
J
J
Rössler
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008202:Lymphangioma / Q000473:pathology* / Q000628:therapy*; D009918:Orbital Neoplasms / Q000473:pathology* / Q000628:therapy*; D010844:Picibanil / Q000627:therapeutic use*; D012597:Sclerosing Solutions / Q000627:therapeutic use*; D015911:Sclerotherapy / Q000379:methods*; D016896:Treatment Outcome
D000970:Antineoplastic Agents; D012597:Sclerosing Solutions; D010844:Picibanil