What physicians should know about the management of chronic hepatitis B in children: East side story.
Understanding the natural course of chronic hepatitis B virus (HBV) infection is very important for the management and treatment of chronic hepatitis B in children. Based on treatment guidelines, the management of HBV carriers and treatment of active hepatitis have been advancing and resulted in increased survival, as well as decreased risks of complications such as liver cirrhosis and hepatocellular carcinoma. Development of a continuing medical education (CME) program for primary physicians becomes an important responsibility of pediatric hepatologists. CME could prevent misdiagnosis and unnecessary treatment that could lead to liver complications or antiviral resistance. In addition, education of patients and their parents is necessary to achieve better therapeutic outcomes.
Seoul National University College of Medicine, Seoul 110-799, South Korea.
Hun-Jee
HJ
Choe
Department of Pediatrics, Kyungpook National University School of Medicine, Daegu 700-721, South Korea
Byung-Ho
BH
Choe
D000998:Antiviral Agents / Q000627:therapeutic use; D001706:Biopsy; D006528:Carcinoma, Hepatocellular / Q000150:complications; D002648:Child; D002675:Child, Preschool; D003951:Diagnostic Errors; D024882:Drug Resistance, Viral; D004502:Education, Medical, Continuing; D006515:Hepatitis B virus / Q000187:drug effects; D019694:Hepatitis B, Chronic / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D019259:Lamivudine / Q000008:administration & dosage; D008103:Liver Cirrhosis / Q000150:complications; D008113:Liver Neoplasms / Q000150:complications; D010372:Pediatrics / Q000379:methods*; D016896:Treatment Outcome
D000998:Antiviral Agents; D019259:Lamivudine
Diagnosis; Hepatitis B virus; Lamivudine; Natural course; Resistance; Treatment