title: Alzheimer's disease and stem cell therapy.
abstract: The loss of neuronal cells in the central nervous system may occur in many neurodegenerative diseases. Alzheimer's disease is a common senile disease in people over 65 years, and it causes impairment characterized by the decline of mental function, including memory loss and cognitive impairment, and affects the quality of life of patients. However, the current therapeutic strategies against AD are only to relieve symptoms, but not to cure it. Because there are only a few therapeutic strategies against Alzheimer's disease, we need to understand the pathogenesis of this disease. Cell therapy may be a powerful tool for the treatment of Alzheimer's disease. This review will discuss the characteristics of Alzheimer's disease and various available therapeutic strategies.
authors.affiliation: Medical Research Institute, Chung-Ang University College of Medicine, Seoul 156-756, Korea.
authors.forename: Sung S
authors.initials: SS
authors.lastname: Choi
authors.affiliation: National Primate Research Center, Korea Research Institute of Bioscience and Biotechnology, Ochang 363-883, Korea.
authors.forename: Sang-Rae
authors.initials: SR
authors.lastname: Lee
authors.affiliation: Division of Neurology, Department of Medicine, University of British Columbia, Vancouver 317-2194, Canada.
authors.forename: Seung U
authors.initials: SU
authors.lastname: Kim
authors.affiliation: Medical Research Institute, Chung-Ang University College of Medicine, Seoul 156-756, Korea.
authors.forename: Hong J
authors.initials: HJ
authors.lastname: Lee
keywords: Alzheimer's disease; stem cell-gene therapy; transplantation
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