title: The impact of patient assistance programs and the 340B Drug Pricing Program on medication cost.
abstract: OBJECTIVE
  Patient assistance programs and the 340B Drug Pricing Program promise to improve the financial stability, better serve vulnerable patients, and decrease the burden of cost for uninsured patients. Our objective is to examine the financial impact that PAPs and the 340B Program have on improving medication cost.
  
  
  METHODS
  Retrospective analysis of medication dispensary data.
  
  
  METHODS
  Dispensary data for uninsured patients obtaining medications at 2 community health centers were collected from February 1 to February 29, 2012. Uninsured patients were divided into 2 samples: (1) patients receiving PAP medications and (2) patients receiving 340B medications. The main outcome measured was the patient's cost savings. Cost savings were calculated based on the amount a medication would have cost had it been purchased by patients at prices found on Epocrates software (drugstore.com). A paired sample t test model using continuous variables was utilized to calculate confidence intervals.
  
  
  RESULTS
  A total of 1420 PAP and 2772 340B individual medications were dispensed to uninsured patients in February 2012. For patients receiving PAP medications the mean ± standard deviation (SD) for age = 52 ± 10. Average cost was $0.11 (95% CI, $0.04-$0.17) and average savings was $617.36 (95% Cl, $581.32-$653.40). For patients receiving 340B medications the mean ±SD for age = 50 ± 14. Average cost was $11.50 (95% CI, $10.55-$12.45). Average saving was $62.31 (95% CI, $57.99-$66.63).
  
  
  CONCLUSIONS
  PAPs and 340B provide significant medication savings for uninsured patient. More research is needed to establish "best practices" for the successful integration of PAPs.
authors.forename: Yelba M
authors.initials: YM
authors.lastname: Castellon
authors.affiliation: Charles R. Drew University of Medicine and Science, 1731 E 120th St, Los Angeles, CA 90059. E-mail: shahrzadbazargan@cdrewu.edu.
authors.forename: Shahrzad
authors.initials: S
authors.lastname: Bazargan-Hejazi
authors.forename: Miles
authors.initials: M
authors.lastname: Masatsugu
authors.forename: Roberto
authors.initials: R
authors.lastname: Contreras
mesh_terms: D017046:Cost Savings / Q000706:statistics & numerical data; D017281:Cost of Illness; D016527:Drug Costs / Q000331:legislation & jurisprudence / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008297:Male; D008483:Medical Assistance / Q000331:legislation & jurisprudence / Q000706:statistics & numerical data*; D017057:Medically Uninsured / Q000706:statistics & numerical data; D008875:Middle Aged; D012189:Retrospective Studies; D014481:United States