title: Disseminated cryptococcosis.
abstract: BACKGROUND
  Fungal infections, especially in immunocompetent children are uncommon causes of fever of unknown origin.
  
  
  METHODS
  A 5-year-old boy with prolonged fever and no evidence of immunosuppression.
  
  
  METHODS
  Ultrasound-guided retroperitoneal lymph node biopsy showed granulomas and intracytoplamic fungal yeasts; staining charactristics were suggestive of cryptococci. Clinical and radiological improvement was seen after treatment with amphoterecin-B.
  
  
  RESULTS
  Disseminated fungal infection should be suspected as a cause of pyrexia of unknown origin after ruling out the commoner causes. Biopsy from enlarged lymph node or organomegaly may yield the diagnosis when non-invasive tests fail.
authors.affiliation: Departments of Pediatrics and *Pathology, All India Institute of Medical Sciences, New Delhi, India. Correspondence to: Dr Madhulika Kabra, Additional Professor, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India. madhulikakabra@hotmail.com.
authors.forename: Meenakshi
authors.initials: M
authors.lastname: Bothra
authors.forename: Prakash
authors.initials: P
authors.lastname: Selvaperumal
authors.forename: Madhulika
authors.initials: M
authors.lastname: Kabra
authors.forename: Prashant
authors.initials: P
authors.lastname: Joshi
mesh_terms: D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002675:Child, Preschool; D003453:Cryptococcosis; D005334:Fever; D006801:Humans; D008198:Lymph Nodes / Q000382:microbiology; D008297:Male
chemical_list: D000935:Antifungal Agents