title: Modeling the kinetics of complex systems: enzymatic hydrolysis of lignocellulosic substrates.
abstract: Lignocellulosic biomass is mainly composed of cellulose, hemicellulose, and lignin. Fuzzy logic, in turn, is a branch of many-valued logic based on the paradigm of inference under vagueness. This paper presents a methodology, based on computational intelligence, for modeling the kinetics of a complex reactional system. The design of a fuzzy interpolator to model cellulose hydrolysis is reported, within the perspective of applying kinetic models in bioreactor engineering. Experimental data for various types of lignocellulosic materials were used to develop the interpolator. New experimental data from the enzymatic hydrolysis of a synthetic substrate, on the other hand, were used to validate the methodology. The accuracy of the results indicates that this is a promising approach to extend the application of models fitted for specific situations to different cases, thus enhancing their generality.
authors.affiliation: Department of Chemical Engineering, Federal University of São Carlos, Rod. Washington Luís, Km 235,CP 676, 13565-905, São Carlos, SP, Brazil.
authors.forename: Carlos Alberto Galeano
authors.initials: CA
authors.lastname: Suarez
authors.forename: Inti Doraci
authors.initials: ID
authors.lastname: Cavalcanti-Montaño
authors.forename: Renan Gustavo
authors.initials: RG
authors.lastname: da Costa Marques
authors.forename: Felipe Fernando
authors.initials: FF
authors.lastname: Furlan
authors.forename: Pedro Luiz
authors.initials: PL
authors.lastname: da Mota e Aquino
authors.forename: Roberto
authors.initials: R
authors.lastname: de Campos Giordano
authors.forename: Ruy
authors.initials: R
authors.lastname: de Sousa
mesh_terms: D000818:Animals; D019149:Bioreactors; D002480:Cellulase / Q000378:metabolism; D016000:Cluster Analysis; D006868:Hydrolysis; D007700:Kinetics; D008031:Lignin / Q000378:metabolism*; D008956:Models, Chemical; D014242:Trichoderma / Q000201:enzymology
chemical_list: C036909:lignocellulose; D008031:Lignin; D002480:Cellulase