title: Incidence of periodontitis in Japanese patients with cardiovascular diseases: a comparison between abdominal aortic aneurysm and arrhythmia.
abstract: Although there is a link between periodontitis and cardiovascular disease (CVD), the influence of periodontitis on CVD is unclear. The aim of this study was to assess the relationship between periodontal bacterial burden and CVD. We studied 142 patients with tachyarrhythmia (TA) and 25 patients with abdominal aortic aneurysm (AAA). We examined periodontitis and the presence of Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans and Prevotella intermedia in the patients' saliva and subgingival plaque using PCR. We also measured serum antibody titers against the pathogens using ELISA. We found that the patients with AAA had fewer remaining teeth (14.6 ± 2.0 vs. 20.9 ± 0.7, P < 0.05) and deeper pocket depth (3.01 ± 0.26 vs. 2.52 ± 0.05 mm, P < 0.05) compared to the TA patients. The existence of each periodontal bacterium in their saliva or subgingival plaque and serum antibody titers was comparable between the two groups. Periodontitis may have a larger affect on aneurysm progression compared to arrhythmia.
authors.affiliation: Department of Advanced Clinical Science and Therapeutics, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 113-8655, Japan, junichisuzuki-circ@umin.ac.jp.
authors.forename: Jun-Ichi
authors.initials: J
authors.lastname: Suzuki
authors.forename: Norio
authors.initials: N
authors.lastname: Aoyama
authors.forename: Mieko
authors.initials: M
authors.lastname: Aoki
authors.forename: Yuko
authors.initials: Y
authors.lastname: Tada
authors.forename: Kouji
authors.initials: K
authors.lastname: Wakayama
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Akazawa
authors.forename: Kunihiro
authors.initials: K
authors.lastname: Shigematsu
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Hoshina
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Izumi
authors.forename: Issei
authors.initials: I
authors.lastname: Komuro
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Miyata
authors.forename: Yasunobu
authors.initials: Y
authors.lastname: Hirata
authors.forename: Mitsuaki
authors.initials: M
authors.lastname: Isobe
mesh_terms: D000368:Aged; D016976:Aggregatibacter actinomycetemcomitans; D017544:Aortic Aneurysm, Abdominal / Q000150:complications*; D044466:Asian People; D003773:Dental Plaque / Q000382:microbiology*; D005260:Female; D006801:Humans; D015994:Incidence; D007564:Japan; D008297:Male; D010518:Periodontitis / Q000150:complications*; D016966:Porphyromonas gingivalis / Q000276:immunology; D018713:Prevotella intermedia; D012463:Saliva / Q000382:microbiology*; D013610:Tachycardia / Q000150:complications*
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