title: Combined central and peripheral demyelination.
abstract: Acquired central and peripheral demyelination in the same patient is a very rare feature. We report a 52-year-male patient with the chronic autoimmune hepatitis (CAH) presenting with pure motor areflexic quadriparesis from 4 months and recent onset of drowsiness of 4 days duration. Studies of imaging and electrophysiology suggested central pontine myelinolysis and chronic inflammatory demyelinating polyradiculoneuropathy. Patient was effectively treated with high dose steroids. To the best of our knowledge, this is the first case of central and peripheral demyelination in a patient with CAH.
authors.affiliation: Department of Neurology, Narayana Medical College and Superspeciality Hospital, Nellore, Andhra Pradesh, India.
authors.forename: Bindu
authors.initials: B
authors.lastname: Menon
authors.affiliation: Department of Neurology, Narayana Medical College and Superspeciality Hospital, Nellore, Andhra Pradesh, India.
authors.forename: Saranjeet Singh
authors.initials: SS
authors.lastname: Bedi
authors.affiliation: Department of Neurology, Narayana Medical College and Superspeciality Hospital, Nellore, Andhra Pradesh, India.
authors.forename: G Uma Maheshwar
authors.initials: GU
authors.lastname: Rao
keywords: Central pontine myelinolysis; chronic autoimmune hepatitis; chronic inflammatory demyelinating polyradiculoneuropathy
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