title: Hot flushes, hormone therapy and alternative treatments: 30 years of experience from Sweden.
abstract: OBJECTIVE
  The use of hormone therapy (HT) for hot flushes has changed dramatically over the past five decades. In this cross-sectional questionnaire study, the aim was to describe the use of HT and alternative treatments and to study the frequency of hot flushes. A further aim was to compare data from the present questionnaire with data from previous studies made in the same geographic area.
  
  
  METHODS
  A questionnaire was sent to a random sample of 2000 women aged 47-56 years living in Östergötland County, Sweden. The results were compared with findings from previous studies regarding use of HT, alternative treatment and hot flushes, and the number of HT prescriptions dispensed during the corresponding time using data derived from the Swedish Prescribed Drug Registry.
  
  
  RESULTS
  The response rate was 66%. Six percent used HT, in line with prevalence data from the Swedish Prescribed Drug Registry. Alternative treatments were used by 10%. About 70% of postmenopausal women reported flushes and almost one-third of those with flushes stated that they would be positive to HT if therapy could be shown to be harmless, a view more often stated by women with severe complaints of hot flushes (67%).
  
  
  CONCLUSIONS
  The use of HT and alternative treatments is low and many women suffer from flushes that could be treated. Women considered their knowledge of the climacteric period and treatment options as insufficient. Individualized information should be given and women with significant climacteric complaints, without contraindications, should be given the opportunity to try HT.
authors.affiliation: Division of Obstetrics and Gynaecology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Department of Obstetrics and Gynaecology in Linköping, County Council of Östergötland , Linköping.
authors.forename: L
authors.initials: L
authors.lastname: Lindh-Åstrand
authors.forename: M
authors.initials: M
authors.lastname: Hoffmann
authors.forename: M
authors.initials: M
authors.lastname: Hammar
authors.forename: A-C
authors.initials: AC
authors.lastname: Spetz Holm
mesh_terms: D000529:Complementary Therapies / Q000706:statistics & numerical data*; D003430:Cross-Sectional Studies; D015914:Estrogen Replacement Therapy / Q000706:statistics & numerical data*; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D019584:Hot Flashes / Q000453:epidemiology / Q000628:therapy*; D006801:Humans; D008875:Middle Aged; D017698:Postmenopause / Q000502:physiology; D015995:Prevalence; D012042:Registries; D011795:Surveys and Questionnaires; D013548:Sweden / Q000453:epidemiology
keywords: COMPLEMENTARY THERAPIES; CROSS-SECTIONAL STUDY; HORMONE THERAPY; HOT FLUSHES; PHARMACOEPIDEMIOLOGY