title: Monoterpenes from the fruits of Amomum kravanh.
abstract: Two new monoterpenes, (7S)-p-cymene-2,7,8-triol (1) and (3R,4R,6S)-p-menth-1-ene-3,6,10-triol (2), were isolated from the fruits of Amomum kravanh. Their structures were established by spectroscopic data. The absolute configuration of the 7,8-diol moiety in 1 was assigned by CD data after addition of Mo2(OAc)4 in dimethyl sulfoxide (DMSO) solution. Compounds 1 and 2 exhibited weak activity of anti-platelet aggregation in vitro.
authors.affiliation: a State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry , China Pharmaceutical University , Nanjing 210009 , China.
authors.forename: Jian-Guang
authors.initials: JG
authors.lastname: Luo
authors.forename: Hong
authors.initials: H
authors.lastname: Yin
authors.forename: Ling-Yi
authors.initials: LY
authors.lastname: Kong
mesh_terms: D035801:Amomum / Q000737:chemistry*; D000818:Animals; D000081007:Cymenes; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005638:Fruit / Q000737:chemistry*; D015394:Molecular Structure; D039821:Monoterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019906:Nuclear Magnetic Resonance, Biomolecular; D010975:Platelet Aggregation Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D011817:Rabbits; D013237:Stereoisomerism; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: C000589363:(3R,4R,6S)-p-menth-1-ene-3,6,10-triol; C000589362:(7S)-p-cymene-2,7,8-triol; D000081007:Cymenes; D004365:Drugs, Chinese Herbal; D039821:Monoterpenes; D010975:Platelet Aggregation Inhibitors; D013729:Terpenes; C007210:4-cymene; C113989:p-menth-1-ene
keywords: Amomum kravanh; Zingiberaceae; monoterpenes