title: Iron-catalyzed radical oxidative coupling reaction of aryl olefins with 1,3-dithiane.
abstract: An alternative method to an iron-catalyzed radical oxidative cross-coupling reaction followed by 2-chloro-1,3-dithiane and aryl olefins for the synthesis of β-chloro substituent 1,3-dithiane products is presented. The described method has the advantage of mildness of the reaction conditions and tolerates a variety of functional groups. Preliminary mechanistic studies have confirmed the first example of a coupling of 1,3-dithiane with unactivated alkenes that proceeds via an iron-catalyzed oxidative radical intermediate along the reaction pathway.
authors.affiliation: School of Pharmacy, Lanzhou University , Lanzhou 730000, P. R. China.
authors.forename: Wenbin
authors.initials: W
authors.lastname: Du
authors.forename: Lixia
authors.initials: L
authors.lastname: Tian
authors.forename: Junshan
authors.initials: J
authors.lastname: Lai
authors.forename: Xing
authors.initials: X
authors.lastname: Huo
authors.forename: Xingang
authors.initials: X
authors.lastname: Xie
authors.forename: Xuegong
authors.initials: X
authors.lastname: She
authors.forename: Shouchu
authors.initials: S
authors.lastname: Tang
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D006571:Heterocyclic Compounds / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction
chemical_list: D000475:Alkenes; D006571:Heterocyclic Compounds; C012947:1,3-dithiane; D007501:Iron