title: Prevention of post-ERCP pancreatitis.
abstract: Over the last 10-15 years there have been refinements in the understanding of risk factors for development of acute post-ERCP pancreatitis (PEP). These risk factors can be divided into patient risks and procedural risks. The most basic way to prevent PEP is avoidance of purely diagnostic ERCP and low-probability ERCP for bile duct stones by use of non-invasive or less-invasive imaging procedures. Improvement in cannulation techniques has led to a reduction in PEP. Placement of prophylactic pancreatic stents and, more recently, use of rectally administered non-steroidal anti-inflammatory agents (NSAIDs) has further reduced the risk of PEP in high-risk patients and/or following high-risk procedures. In this review the methods for prevention of PEP will be discussed.
authors.affiliation: Division of Gastroenterology and Hepatology University of North Carolina, Chapel Hill, NC, USA - todd_baron@med.unc.edu.
authors.forename: T H
authors.initials: TH
authors.lastname: Baron
authors.forename: S
authors.initials: S
authors.lastname: Irani
mesh_terms: D000285:Administration, Rectal; D000367:Age Factors; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage; D002404:Catheterization / Q000009:adverse effects / Q000379:methods; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000009:adverse effects* / Q000379:methods; D005440:Fluid Therapy / Q000379:methods; D006801:Humans; D010195:Pancreatitis / Q000000981:diagnostic imaging / Q000209:etiology / Q000517:prevention & control*; D012307:Risk Factors; D012737:Sex Factors; D015607:Stents; D014057:Tomography, X-Ray Computed
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal