title: Acute ocular myositis occurring under etanercept for rheumatoid arthritis.
abstract: Ocular myositis is a rare disorder characterized by inflammation of single or multiple extra-ocular eye muscles presenting with painful diplopia and/or ophthalmoplegia. The etiology remains obscure and it is rarely associated with rheumatoid arthritis. We here reported the case of a 61-year-old woman treated by TNF-α blockade, namely etanercept, for rheumatoid arthritis for ten years who developed an acute ocular myositis. The patient improved after etanercept was stopped and initiation of high doses of corticosteroids. To our knowledge, this is the second report of ocular myositis occurring under TNF-α blockade treatment for rheumatoid arthritis.
authors.affiliation: Rheumatology Department, Clermont-Ferrand Teaching Hospital, place Henri-Dunant, 63000 Clermont-Ferrand, France. Electronic address: mcouderc@chu-clermontferrand.fr.
authors.forename: Marion
authors.initials: M
authors.lastname: Couderc
authors.affiliation: Rheumatology Department, Clermont-Ferrand Teaching Hospital, place Henri-Dunant, 63000 Clermont-Ferrand, France.
authors.forename: Sylvain
authors.initials: S
authors.lastname: Mathieu
authors.affiliation: Rheumatology Department, Clermont-Ferrand Teaching Hospital, place Henri-Dunant, 63000 Clermont-Ferrand, France.
authors.forename: Anne
authors.initials: A
authors.lastname: Tournadre
authors.affiliation: Rheumatology Department, Clermont-Ferrand Teaching Hospital, place Henri-Dunant, 63000 Clermont-Ferrand, France.
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Dubost
authors.affiliation: Rheumatology Department, Clermont-Ferrand Teaching Hospital, place Henri-Dunant, 63000 Clermont-Ferrand, France.
authors.forename: Martin
authors.initials: M
authors.lastname: Soubrier
mesh_terms: D018501:Antirheumatic Agents / Q000009:adverse effects*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D000068800:Etanercept; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007074:Immunoglobulin G / Q000009:adverse effects*; D008875:Middle Aged; D055622:Orbital Myositis / Q000209:etiology / Q000628:therapy*; D018124:Receptors, Tumor Necrosis Factor; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
chemical_list: D018501:Antirheumatic Agents; D005938:Glucocorticoids; D007074:Immunoglobulin G; D018124:Receptors, Tumor Necrosis Factor; D014409:Tumor Necrosis Factor-alpha; D000068800:Etanercept
keywords: Etanercept; Ocular myositis; Rheumatoid arthritis; TNF-α blocker