title: Ophthalmoplegia starting with a headache circumscribed in a line-shaped area: a subtype of ophthalmoplegic migraine?
abstract: Recurrent painful ophthalmoplegic neuropathy (RPON), formerly named ophthalmoplegic migraine (OM), is a rare condition characterized by the association of unilateral headaches and the ipsilateral oculomotor nerve palsy. The third cranial nerve is most commonly involved in the recurrent attacks. But it is still debated whether a migraine or an oculomotor neuropathy may be the primary cause of this disorder. Here, we report an elder patient who had a recurrent ophthalmoplegia starting with an unilateral headache circumscribed in an area shaped in a line linking the posterior-parietal region and the ipsilateral eye. And the headache had couple of features similar to that of migraine, such as past history of recurrent migraine attacks, accompaniments of nausea, vomiting, and phonophobia, response to flunarizine and sodium valproate. We may herein report a subtype of OM but not a RPON. This case report indicates that OM may exist as an entity and some OM may be wrongly grouped under the category of RPON in the current international headache classification.
authors.affiliation: Department of Neurology, Epilepsy and Headache group, the First Hospital of Anhui Medical University, Jixi Road 218, Hefei 230022, China. yw4d@hotmail.com.
authors.forename: Yu
authors.initials: Y
authors.lastname: Wang
authors.forename: Xian-Hong
authors.initials: XH
authors.lastname: Wang
authors.forename: Miao-Miao
authors.initials: MM
authors.lastname: Tian
authors.forename: Cheng-Juan
authors.initials: CJ
authors.lastname: Xie
authors.forename: Ying
authors.initials: Y
authors.lastname: Liu
authors.forename: Qing-Qing
authors.initials: QQ
authors.lastname: Pan
authors.forename: Ya-Nan
authors.initials: YN
authors.lastname: Lu
mesh_terms: D006261:Headache / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D009886:Ophthalmoplegia / Q000150:complications* / Q000175:diagnosis*; D060486:Ophthalmoplegic Migraine / Q000145:classification / Q000503:physiopathology*; D015898:Tomography Scanners, X-Ray Computed
references.citation: Cephalalgia. 2018 Jan;38(1):1-211
references.pmid: 29368949
references.citation: Pain Med. 2013 May;14(5):765-6
references.pmid: 23565901
references.citation: J Neurosci. 2010 Jun 30;30(26):8807-14
references.pmid: 20592202
references.citation: Cephalalgia. 2010 Jun;30(6):655-61
references.pmid: 19673904
references.citation: Headache. 2009 Jun;49(6):838-50
references.pmid: 19389140
references.citation: Cephalalgia. 1988;8 Suppl 7:1-96
references.pmid: 3048700
references.citation: Cephalalgia. 2001 Mar;21(2):84-9
references.pmid: 11422088
references.citation: Cephalalgia. 2012 Dec;32(16):1208-15
references.pmid: 23150890
references.citation: Brain Res. 1970 Jun 3;20(2):219-31
references.pmid: 5511233
references.citation: Cephalalgia. 2012 Jan;32(1):3-5
references.pmid: 22174361
references.citation: J Headache Pain. 2010 Feb;11(1):75-8
references.pmid: 19936614
references.citation: Cephalalgia. 2008 Mar;28(3):257-63
references.pmid: 18201251
references.citation: Headache. 2013 May;53(5):764-74
references.pmid: 23573949
references.citation: Cephalalgia. 2014 Apr;34(4):243-57
references.pmid: 24126945
references.citation: Pain Med. 2013 Mar;14(3):358-61
references.pmid: 23279627
references.citation: Headache. 2010 Mar;50(3):451-8
references.pmid: 20100299
references.citation: J Clin Invest. 2009 Jan;119(1):99-109
references.pmid: 19104150
references.citation: Ann Neurol. 2011 May;69(5):855-65
references.pmid: 21416489
references.citation: PLoS One. 2009 Jun 08;4(6):e5827
references.pmid: 19503794
references.citation: Curr Pain Headache Rep. 2012 Jun;16(3):270-7
references.pmid: 22328144
references.citation: J Child Neurol. 2012 Jun;27(6):759-66
references.pmid: 22241707
references.citation: J Headache Pain. 2011 Oct;12(5):535-9
references.pmid: 21618032
references.citation: J Neurosci. 2011 Apr 13;31(15):5755-63
references.pmid: 21490217
references.citation: Physiol Behav. 1977 Nov;19(5):673-7
references.pmid: 605176