title: An investigation of outpatient children's blood lead level in Wuhan China.
abstract: OBJECTIVE
  Blood lead levels (BLLs) and possible influencing factors in children in Wuhan China were investigated in order to understand current lead pollution exposure and provide a scientific basis for prevention and policy making.
  
  
  METHODS
  BLL data were collected from 15,536 out-patients in Wuhan Children Hospital in 2012 full year. All of them were under 18 years of age (Mean ± SD: 4.32 ± 3.2, 64.4% boys). The BLLs were measured by an atomic absorption spectrometry (BH2100).
  
  
  RESULTS
  The geometric mean of BLLs for all the subjects was 44.75 µg/L (95%CI: 44.46 µg/L - 45.05 µg/L), much lower than that reported in previous studies. The prevalence of the elevated BLLs (≥ 100 µg/L) in the children tested was 2% in 2012 and the prevalence of BLLs (≥ 50 µg/L) was 44%. Age and sex could be possible influencing factors for BLLs in the children (p<0.001). In addition, the BLLs in different seasons were different (p<0.001).
  
  
  CONCLUSIONS
  These results demonstrate that BLLs have significantly decreased in children in Wuhan during recent years. However, we should continuously pay attention to lead pollution and emphasize that prevention is much more important than treatment for controlling children's BLLs.
authors.affiliation: Wuhan Children's Hospital, Wuhan, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Li
authors.affiliation: School of Public Health, Wuhan University, Wuhan, China.
authors.forename: Siqi
authors.initials: S
authors.lastname: Wu
authors.affiliation: Wuhan Children's Hospital, Wuhan, China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Xiang
authors.affiliation: School of Public Health, Wuhan University, Wuhan, China.
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Liang
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007854:Lead / Q000097:blood* / Q000633:toxicity; D007855:Lead Poisoning / Q000097:blood / Q000453:epidemiology*; D008297:Male; D010045:Outpatients; D015995:Prevalence; D012621:Seasons; D012737:Sex Factors
chemical_list: D007854:Lead
references.citation: Zhonghua Liu Xing Bing Xue Za Zhi. 2002 Jun;23(3):162-6
references.pmid: 12411080
references.citation: Environ Res. 2006 Jul;101(3):412-8
references.pmid: 16442092
references.citation: Pediatr Clin North Am. 2007 Apr;54(2):271-94, viii
references.pmid: 17448360
references.citation: Pediatrics. 2004 Apr;113(4 Suppl):1016-22
references.pmid: 15060194
references.citation: MMWR Morb Mortal Wkly Rep. 2000 Dec 22;49(50):1133-7
references.pmid: 11190117
references.citation: Mutat Res. 2008 Jul-Aug;659(1-2):166-75
references.pmid: 18436472
references.citation: Biol Trace Elem Res. 2012 Nov;149(2):143-7
references.pmid: 22528781
references.citation: J Health Popul Nutr. 2012 Dec;30(4):404-9
references.pmid: 23304906
references.citation: MMWR Morb Mortal Wkly Rep. 2013 Apr 5;62(13):245-8
references.pmid: 23552225
references.citation: Environ Health Perspect. 2006 May;114(5):791-7
references.pmid: 16675439
references.citation: Paediatr Perinat Epidemiol. 2012 Jan;26(1):61-9
references.pmid: 22150709
references.citation: Environ Health Prev Med. 2012 Jan;17(1):27-33
references.pmid: 21516304
references.citation: Sci Total Environ. 2009 Jun 15;407(13):3986-93
references.pmid: 19395068