title: Latest progress in tyrosine kinase inhibitors.
abstract: Here we discuss the latest progress in development of some kinase inhibitors such as inhibitors of c-MET, LIM and Bcr-Abl kinases. Importantly, many oncogenic kinases signal via the mTOR pathway, suggesting a common target for drug combinations.
authors.forename: Tatiana V
authors.initials: TV
authors.lastname: Pospelova
authors.forename: Valery A
authors.initials: VA
authors.lastname: Pospelov
mesh_terms: D006801:Humans; D054461:Lim Kinases / Q000037:antagonists & inhibitors; D016328:NF-kappa B / Q000037:antagonists & inhibitors; D009369:Neoplasms / Q000188:drug therapy*; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors*; D019859:Proto-Oncogene Proteins c-met / Q000037:antagonists & inhibitors; D015398:Signal Transduction; D058570:TOR Serine-Threonine Kinases / Q000037:antagonists & inhibitors
chemical_list: D016328:NF-kappa B; D011505:Protein-Tyrosine Kinases; D019859:Proto-Oncogene Proteins c-met; D054461:Lim Kinases; D058570:TOR Serine-Threonine Kinases
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