title: Discordance between train-of-four response and clinical symptoms in a patient with amyotrophic lateral sclerosis.
abstract: A 47-year-old woman with amyotrophic lateral sclerosis was scheduled for total thyroidectomy with cervical node dissection. During anesthetic management by total intravenous anesthesia using remifentanil, propofol, and rocuronium, train-of-four (TOF) monitoring findings were not consistent with clinical signs. Sugammadex successfully reversed shallow respiration.
authors.affiliation: Department of Anesthesiology and Pain Medicine, Gachon University Gil Medical Center, Incheon 405-760, Korea.
authors.forename: Young Jin
authors.initials: YJ
authors.lastname: Chang
authors.forename: Wol Seon
authors.initials: WS
authors.lastname: Jung
authors.forename: Woon Rak
authors.initials: WR
authors.lastname: Son
authors.forename: Young Yi
authors.initials: YY
authors.lastname: Jo
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000150:complications*; D000732:Androstanols / Q000627:therapeutic use; D000771:Anesthesia, Intravenous / Q000379:methods*; D018686:Anesthetics, Intravenous / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007431:Intraoperative Complications / Q000209:etiology*; D008197:Lymph Node Excision; D008875:Middle Aged; D003473:Neuromuscular Nondepolarizing Agents / Q000627:therapeutic use; D010880:Piperidines / Q000627:therapeutic use; D015742:Propofol / Q000627:therapeutic use; D000077208:Remifentanil; D012131:Respiratory Insufficiency / Q000209:etiology*; D000077123:Rocuronium; D000077122:Sugammadex; D013965:Thyroidectomy; D047408:gamma-Cyclodextrins / Q000627:therapeutic use
chemical_list: D000732:Androstanols; D018686:Anesthetics, Intravenous; D003473:Neuromuscular Nondepolarizing Agents; D010880:Piperidines; D047408:gamma-Cyclodextrins; D000077122:Sugammadex; D000077208:Remifentanil; D000077123:Rocuronium; D015742:Propofol