title: Mind the gap: why many geneticists and psychological scientists have discrepant views about gene-environment interaction (G×E) research.
abstract: As our field seeks to elucidate the biopsychosocial etiologies of mental health disorders, many traditional psychological and social science researchers have added, or plan to add, genetic components to their programs of research. An understanding of the history, methods, and perspectives of the psychiatric genetics community is useful in this pursuit. In this article we provide a brief overview of psychiatric genetic methods and findings. This overview lays the groundwork for a more thorough review of gene-environment interaction (G×E) research and the candidate gene approach to G×E research that remains popular among many psychologists and social scientists. We describe the differences in perspective between psychiatric geneticists and psychological scientists that have contributed to a growing divide between the research cited and conducted by these two related disciplines. Finally, we outline a strategy for the future of research on gene-environment interactions that capitalizes on the relative strengths of each discipline. (PsycINFO Database Record (c) 2014 APA, all rights reserved).
authors.affiliation: Department of Psychiatry, Harvard Medical School.
authors.forename: Laramie E
authors.initials: LE
authors.lastname: Duncan
authors.affiliation: Department of Psychiatry, Harvard Medical School.
authors.forename: Alisha R
authors.initials: AR
authors.lastname: Pollastri
authors.affiliation: Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research ,Massachusetts General Hospital.
authors.forename: Jordan W
authors.initials: JW
authors.lastname: Smoller
mesh_terms: D059647:Gene-Environment Interaction; D006801:Humans; D001523:Mental Disorders / Q000235:genetics* / Q000523:psychology*; D017594:Publication Bias; D012106:Research; D012931:Social Environment
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