title: Dielectric response of shelled toroidal particles carrying localized surface charge distributions. The effect of concentric and confocal shells.
abstract: Dielectric models of biological cells are generally based on spherical or ellipsoidal geometries, where the different adjoining dielectric media are arranged as distinct core and shells, representing the cytosol and the cell membrane. For ellipsoidal particles, this approach implies the assumption of confocal shells that, in turn, means a cell membrane of ill-defined thickness. A quantitative analysis of the influence of a non-uniform thickness of the cell membrane has been not considered so far. In the case of a toroidal particle, this problem can be conveniently addressed by considering the solution of the Laplace equation in two different coordinate systems, i.e., toroidal coordinates (confocal shells and hence non-uniform thickness of the shell membrane) and toroidal polar coordinate, (concentric shells and hence a uniform thickness of the shell membrane). In the present paper, we compare the dielectric spectra of a toroidal particle aqueous suspension obtained from the two above stated solutions of the Laplace equation and we furnish a first quantitative estimate of the differences arising from considering the presence of confocal or concentric shells. This approach offers a complete view of the influence of the membrane thickness on the whole dielectric spectrum of a biological particle suspension, at least as far as toroidal objects are concerned.
authors.affiliation: Department of Physics, University of Camerino, Camerino, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Di Biasio
authors.affiliation: Department of Biosciences and Territory, University of Molise, I-86000 Pesche, Isernia, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Ambrosone
authors.affiliation: Department of Physics, University of Rome "La Sapienza" and INFM-CRS-SOFT, Unita' di Roma1, I-00185 Rome, Italy. Electronic address: cesare.cametti@roma1.infn.it.
authors.forename: C
authors.initials: C
authors.lastname: Cametti
mesh_terms: D002462:Cell Membrane / Q000502:physiology*; D016764:Cell Polarity; D048430:Cell Shape; D003198:Computer Simulation; D017097:Electric Impedance; D004594:Electrophysiology; D008954:Models, Biological; D013535:Suspensions
chemical_list: D013535:Suspensions
keywords: Conductivity of cell membrane; Dielectric spectroscopy technique; Permittivity of cell membrane; Toroidal particles