title: methylC Track: visual integration of single-base resolution DNA methylation data on the WashU EpiGenome Browser.
abstract: CONCLUSIONS
  We present methylC track, an efficient mechanism for visualizing single-base resolution DNA methylation data on a genome browser. The methylC track dynamically integrates the level of methylation, the position and context of the methylated cytosine (i.e. CG, CHG and CHH), strand and confidence level (e.g. read coverage depth in the case of whole-genome bisulfite sequencing data). Investigators can access and integrate these information visually at specific locus or at the genome-wide level on the WashU EpiGenome Browser in the context of other rich epigenomic datasets.
  
  
  METHODS
  The methylC track is part of the WashU EpiGenome Browser, which is open source and freely available at http://epigenomegateway.wustl.edu/browser/. The most up-to-date instructions and tools for preparing methylC track are available at http://epigenomegateway.wustl.edu/+/cmtk.
  
  
  BACKGROUND
  twang@genetics.wustl.edu
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors.affiliation: Department of Genetics, Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA and Department of Neurosurgery, Brain Tumor Research Center, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, USA.
authors.forename: Xin
authors.initials: X
authors.lastname: Zhou
authors.affiliation: Department of Genetics, Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA and Department of Neurosurgery, Brain Tumor Research Center, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, USA.
authors.forename: Daofeng
authors.initials: D
authors.lastname: Li
authors.affiliation: Department of Genetics, Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA and Department of Neurosurgery, Brain Tumor Research Center, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, USA.
authors.forename: Rebecca F
authors.initials: RF
authors.lastname: Lowdon
authors.affiliation: Department of Genetics, Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA and Department of Neurosurgery, Brain Tumor Research Center, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, USA.
authors.forename: Joseph F
authors.initials: JF
authors.lastname: Costello
authors.affiliation: Department of Genetics, Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA and Department of Neurosurgery, Brain Tumor Research Center, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, USA.
authors.forename: Ting
authors.initials: T
authors.lastname: Wang
mesh_terms: D019175:DNA Methylation / Q000187:drug effects; D030541:Databases, Genetic; D057890:Epigenomics / Q000379:methods*; D015894:Genome, Human / Q000235:genetics; D006801:Humans; D017422:Sequence Analysis, DNA; D013447:Sulfites / Q000494:pharmacology; D064878:Web Browser
chemical_list: D013447:Sulfites; C042345:hydrogen sulfite
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