title: First isolation of border disease virus in Japan is from a pig farm with no ruminants.
abstract: The first isolation of border disease virus (BDV) in Japan was from a pig farm of the farrow-to-finishing type that kept no small ruminants or cattle. The infection was detected in the course of sero-surveillance for classical swine fever virus (CSFV) in Japan. The infected pigs had no clinical symptoms of CSFV or other disease; nevertheless, a high sero-positive rate of 58.5% was identified. A persistently infected pig with the BDV was found and suspected to be the cause of sero-prevalence in the farm. The isolated BDV was genetically close to BDV strains from New Zealand, but there was no epidemiological evidence concerning the route(s) of the invasion into the farm.
authors.affiliation: Ibaraki Prefectural Western District Livestock Health and Hygiene Office, 42-4 Araishinden, Chikusei, Ibaraki 300-4516, Japan.
authors.forename: Nahoko
authors.initials: N
authors.lastname: Kawanishi
authors.affiliation: Ibaraki Prefectural Northern District Livestock Health and Hygiene Office, 966-1 Nakakawachi-cho, Mito, Ibaraki 310-0002, Japan.
authors.forename: Satoko
authors.initials: S
authors.lastname: Tsuduku
authors.affiliation: Ibaraki Prefectural Rokko District Livestock Health and Hygiene Office, 1367-3 Hokota, Hokota, Ibaraki 311-1517, Japan.
authors.forename: Hiromi
authors.initials: H
authors.lastname: Shimizu
authors.affiliation: Ibaraki Prefectural Northern District Livestock Health and Hygiene Office, 966-1 Nakakawachi-cho, Mito, Ibaraki 310-0002, Japan.
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Ohtani
authors.affiliation: Viral Diseases and Epidemiology Research Division, National Institute of Animal Health, NARO, 3-1-5 Kan-nondai, Tsukuba, Ibaraki 305-0856, Japan.
authors.forename: Ken-Ichiro
authors.initials: K
authors.lastname: Kameyama
authors.affiliation: Viral Diseases and Epidemiology Research Division, National Institute of Animal Health, NARO, 3-1-5 Kan-nondai, Tsukuba, Ibaraki 305-0856, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Yamakawa
authors.affiliation: Viral Diseases and Epidemiology Research Division, National Institute of Animal Health, NARO, 3-1-5 Kan-nondai, Tsukuba, Ibaraki 305-0856, Japan.
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Tsutsui
authors.affiliation: Center for Animal Disease Control and Prevention, National Institute of Animal Health, NARO, 3-1-5 Kan-nondai, Tsukuba, Ibaraki 305-0856, Japan.
authors.forename: Katsuyoshi
authors.initials: K
authors.lastname: Matsuura
authors.affiliation: Exotic Diseases Research Division, National Institute of Animal Health, NARO, 6-20-1 Jousuihon-cho, Kodaira, Tokyo 187-0022, Japan.
authors.forename: Seiichi
authors.initials: S
authors.lastname: Ohashi
authors.affiliation: Center for Animal Disease Control and Prevention, National Institute of Animal Health, NARO, 3-1-5 Kan-nondai, Tsukuba, Ibaraki 305-0856, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Isobe
authors.affiliation: Center for Animal Disease Control and Prevention, National Institute of Animal Health, NARO, 3-1-5 Kan-nondai, Tsukuba, Ibaraki 305-0856, Japan; Exotic Diseases Research Division, National Institute of Animal Health, NARO, 6-20-1 Jousuihon-cho, Kodaira, Tokyo 187-0022, Japan. Electronic address: musasabi@affrc.go.jp.
authors.forename: Shunji
authors.initials: S
authors.lastname: Yamada
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D018083:Border disease virus / Q000302:isolation & purification*; D007564:Japan; D009520:New Zealand; D012418:Ruminants / Q000821:virology; D013552:Swine / Q000821:virology*
chemical_list: D000914:Antibodies, Viral
keywords: Border disease virus; CSF; Genetic analysis; PI pig; Pestivirus