title: Rh(III)-catalyzed oxidative coupling of 1,2-disubstituted arylhydrazines and olefins: a new strategy for 2,3-dihydro-1H-indazoles.
abstract: A rhodium(III)-catalyzed oxidative olefination of 1,2-disubstituted arylhydrazines with alkenes via sp(2) C-H bond activation followed by an intramolecular aza-Michael reaction is described. This strategy allows the direct and efficient construction of highly substituted 2,3-dihydro-1H-indazole scaffolds.
authors.affiliation: School of Pharmacy, Sungkyunkwan University , Suwon 440-746, Republic of Korea.
authors.forename: Sangil
authors.initials: S
authors.lastname: Han
authors.forename: Youngmi
authors.initials: Y
authors.lastname: Shin
authors.forename: Satyasheel
authors.initials: S
authors.lastname: Sharma
authors.forename: Neeraj Kumar
authors.initials: NK
authors.lastname: Mishra
authors.forename: Jihye
authors.initials: J
authors.lastname: Park
authors.forename: Mirim
authors.initials: M
authors.lastname: Kim
authors.forename: Minyoung
authors.initials: M
authors.lastname: Kim
authors.forename: Jinbong
authors.initials: J
authors.lastname: Jang
authors.forename: In Su
authors.initials: IS
authors.lastname: Kim
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D006834:Hydrazines / Q000737:chemistry*; D007191:Indazoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D058451:Oxidative Coupling; D012238:Rhodium / Q000737:chemistry*
chemical_list: D000475:Alkenes; D006834:Hydrazines; D007191:Indazoles; D012238:Rhodium