title: Optic nerve glioma: an update.
abstract: Optic nerve glioma is the most common optic nerve tumour. However, it has an unpredictable natural history. The treatment of optic nerve gliomas has changed considerably over the past few years. Chemotherapy and radiation therapy can now stabilize and in some cases improve the vision of patients with optic nerve gliomas. The treatment of optic nerve glioma requires a multi-disciplinary approach where all treatment options may have to be implemented in a highly individualized manner. The aim of this review article is to present current diagnostic and treatment protocols for optic nerve glioma.
authors.affiliation: Department of Neuro-Ophthalmology, Sankara Nethralaya, A Unit of Medical Research Foundation, 18 College Road, Nungambakkam, Chennai, 600 006, India, akshaygn@gmail.com.
authors.forename: Akshay Gopinathan
authors.initials: AG
authors.lastname: Nair
authors.forename: Rima S
authors.initials: RS
authors.lastname: Pathak
authors.forename: Veena R
authors.initials: VR
authors.lastname: Iyer
authors.forename: Rashmin A
authors.initials: RA
authors.lastname: Gandhi
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D020339:Optic Nerve Glioma / Q000175:diagnosis / Q000628:therapy; D018714:Radiotherapy, Adjuvant / Q000379:methods; D041623:Tomography, Optical Coherence
chemical_list: D000970:Antineoplastic Agents
references.citation: Am J Ophthalmol. 1980 Feb;89(2):284-92
references.pmid: 6243868
references.citation: J Clin Oncol. 1993 May;11(5):850-6
references.pmid: 8487049
references.citation: Arch Ophthalmol. 2005 May;123(5):694-700
references.pmid: 15883294
references.citation: Am J Ophthalmol. 2001 Apr;131(4):442-5
references.pmid: 11292406
references.citation: Strahlenther Onkol. 2003 Aug;179(8):509-20
references.pmid: 14509949
references.citation: Eur J Radiol. 2010 May;74(2):299-313
references.pmid: 20413240
references.citation: J Neurooncol. 2003 Jul;63(3):289-94
references.pmid: 12892235
references.citation: Surv Ophthalmol. 1994 Mar-Apr;38(5):427-52
references.pmid: 8009427
references.citation: Int J Radiat Oncol Biol Phys. 1990 Apr;18(4):927-32
references.pmid: 2323979
references.citation: Eye (Lond). 2004 Nov;18(11):1026-37
references.pmid: 15534587
references.citation: Ann Neurol. 2007 Mar;61(3):189-98
references.pmid: 17387725
references.citation: Pediatr Neurosurg. 2000 Sep;33(3):151-8
references.pmid: 11096362
references.citation: Int J Radiat Oncol Biol Phys. 2005 Jul 1;62(3):814-9
references.pmid: 15936565
references.citation: Cancer. 1977 Nov;40(5):2079-80
references.pmid: 922656
references.citation: Curr Opin Ophthalmol. 1994 Dec;5(6):11-7
references.pmid: 10150823
references.citation: J Clin Neurosci. 2011 Dec;18(12):1585-91
references.pmid: 22071462
references.citation: Curr Opin Neurol. 2009 Feb;22(1):11-8
references.pmid: 19155759
references.citation: Eur J Pediatr. 1990 Sep;149(12):825-8
references.pmid: 2226566
references.citation: Int J Radiat Oncol Biol Phys. 1993 Jan 15;25(2):215-25
references.pmid: 8420869
references.citation: Indian J Ophthalmol. 2011 Mar-Apr;59(2):111-6
references.pmid: 21350280
references.citation: J Neurosurg. 1997 May;86(5):747-54
references.pmid: 9126887
references.citation: Neurol Clin. 1991 Feb;9(1):163-77
references.pmid: 2011108
references.citation: Eur J Pediatr. 2000 Sep;159(9):692-6
references.pmid: 11014471
references.citation: Cancer. 2003 Feb 15;97(4):1084-92
references.pmid: 12569610
references.citation: Br J Cancer. 2003 Dec 1;89(11):2038-44
references.pmid: 14647135
references.citation: Radiology. 1956 Apr;66(4):518-28
references.pmid: 13323290
references.citation: Childs Nerv Syst. 1995 Aug;11(8):443-8
references.pmid: 7585679
references.citation: Neuroimaging Clin N Am. 2005 Feb;15(1):175-201
references.pmid: 15927867
references.citation: Can J Ophthalmol. 1997 Oct;32(6):409-13
references.pmid: 9363346
references.citation: J Child Neurol. 2003 Jul;18(7):471-8
references.pmid: 12940652
references.citation: Cancer. 1990 Jan 1;65(1):45-52
references.pmid: 2104571
references.citation: Int J Radiat Oncol Biol Phys. 1997 Oct 1;39(3):579-87
references.pmid: 9336136
references.citation: Cancer. 1980 Mar 15;45(6):1467-71
references.pmid: 7357527
references.citation: Radiographics. 2007 Jul-Aug;27(4):1159-86
references.pmid: 17620473
references.citation: Acta Neuropathol. 2000 May;99(5):563-70
references.pmid: 10805102
references.citation: J Neurosurg. 1993 Jul;79(1):32-5
references.pmid: 8315466
references.citation: Arch Dis Child. 1998 Oct;79(4):334-8
references.pmid: 9875044