title: Dual-color imaging of cytosolic and mitochondrial zinc ions in live tissues with two-photon fluorescent probes.
abstract: We report two-photon probes for Zn(2+) ions that can simultaneously detect cytosolic and mitochondrial Zn(2+) ions in live cells and living tissues at 115 mm depth by dual-color TPM imaging with minimum interference from other biologically relevant species.
authors.affiliation: Department of Chemistry, Korea University, 1-Anamdong, Seoul, Korea. chobr@korea.ac.kr.
authors.forename: Kailash
authors.initials: K
authors.lastname: Rathore
authors.forename: Chang Su
authors.initials: CS
authors.lastname: Lim
authors.forename: Young
authors.initials: Y
authors.lastname: Lee
authors.forename: Bong Rae
authors.initials: BR
authors.lastname: Cho
mesh_terms: D000818:Animals; D002470:Cell Survival; D003116:Color; D003600:Cytosol / Q000378:metabolism*; D005456:Fluorescent Dyes / Q000378:metabolism*; D006367:HeLa Cells; D006624:Hippocampus / Q000166:cytology; D006801:Humans; D007477:Ions; D008928:Mitochondria / Q000378:metabolism*; D057054:Molecular Imaging / Q000379:methods*; D009928:Organ Specificity; D017785:Photons; D051381:Rats; D013050:Spectrometry, Fluorescence; D015032:Zinc
chemical_list: D005456:Fluorescent Dyes; D007477:Ions; D015032:Zinc