title: The multi-modal Australian ScienceS Imaging and Visualization Environment (MASSIVE) high performance computing infrastructure: applications in neuroscience and neuroinformatics research.
abstract: The Multi-modal Australian ScienceS Imaging and Visualization Environment (MASSIVE) is a national imaging and visualization facility established by Monash University, the Australian Synchrotron, the Commonwealth Scientific Industrial Research Organization (CSIRO), and the Victorian Partnership for Advanced Computing (VPAC), with funding from the National Computational Infrastructure and the Victorian Government. The MASSIVE facility provides hardware, software, and expertise to drive research in the biomedical sciences, particularly advanced brain imaging research using synchrotron x-ray and infrared imaging, functional and structural magnetic resonance imaging (MRI), x-ray computer tomography (CT), electron microscopy and optical microscopy. The development of MASSIVE has been based on best practice in system integration methodologies, frameworks, and architectures. The facility has: (i) integrated multiple different neuroimaging analysis software components, (ii) enabled cross-platform and cross-modality integration of neuroinformatics tools, and (iii) brought together neuroimaging databases and analysis workflows. MASSIVE is now operational as a nationally distributed and integrated facility for neuroinfomatics and brain imaging research.
authors.affiliation: Monash eResearch Centre, Monash University Clayton, VIC, Australia.
authors.forename: Wojtek J
authors.initials: WJ
authors.lastname: Goscinski
authors.affiliation: Monash eResearch Centre, Monash University Clayton, VIC, Australia.
authors.forename: Paul
authors.initials: P
authors.lastname: McIntosh
authors.affiliation: Australian Synchrotron Clayton, VIC, Australia.
authors.forename: Ulrich
authors.initials: U
authors.lastname: Felzmann
authors.affiliation: Australian Synchrotron Clayton, VIC, Australia.
authors.forename: Anton
authors.initials: A
authors.lastname: Maksimenko
authors.affiliation: Australian Synchrotron Clayton, VIC, Australia.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Hall
authors.affiliation: CSIRO Clayton, VIC, Australia.
authors.forename: Timur
authors.initials: T
authors.lastname: Gureyev
authors.affiliation: CSIRO Clayton, VIC, Australia.
authors.forename: Darren
authors.initials: D
authors.lastname: Thompson
authors.affiliation: Centre for Advanced Imaging, University of Queensland St Lucia, QLD, Australia.
authors.forename: Andrew
authors.initials: A
authors.lastname: Janke
authors.affiliation: Centre for Advanced Imaging, University of Queensland St Lucia, QLD, Australia.
authors.forename: Graham
authors.initials: G
authors.lastname: Galloway
authors.affiliation: The University of Melbourne Melbourne, VIC, Australia.
authors.forename: Neil E B
authors.initials: NE
authors.lastname: Killeen
authors.affiliation: Monash Biomedical Imaging, Monash University Clayton, VIC, Australia ; CSIRO Preventative Health Flagship, CSIRO Computational Informatics, The Australian e-Health Research Centre Herston, QLD, Australia.
authors.forename: Parnesh
authors.initials: P
authors.lastname: Raniga
authors.affiliation: Monash eResearch Centre, Monash University Clayton, VIC, Australia ; Monash Biomedical Imaging, Monash University Clayton, VIC, Australia.
authors.forename: Owen
authors.initials: O
authors.lastname: Kaluza
authors.affiliation: Monash eResearch Centre, Monash University Clayton, VIC, Australia ; Monash Biomedical Imaging, Monash University Clayton, VIC, Australia ; Life Sciences Computation Centre, VLSCI Parkville, VIC, Australia.
authors.forename: Amanda
authors.initials: A
authors.lastname: Ng
authors.affiliation: Monash Biomedical Imaging, Monash University Clayton, VIC, Australia.
authors.forename: Govinda
authors.initials: G
authors.lastname: Poudel
authors.affiliation: Monash eResearch Centre, Monash University Clayton, VIC, Australia ; Monash Biomedical Imaging, Monash University Clayton, VIC, Australia ; Life Sciences Computation Centre, VLSCI Parkville, VIC, Australia.
authors.forename: David G
authors.initials: DG
authors.lastname: Barnes
authors.affiliation: Monash Biomedical Imaging, Monash University Clayton, VIC, Australia.
authors.forename: Toan
authors.initials: T
authors.lastname: Nguyen
authors.affiliation: Monash eResearch Centre, Monash University Clayton, VIC, Australia.
authors.forename: Paul
authors.initials: P
authors.lastname: Bonnington
authors.affiliation: Monash Biomedical Imaging, Monash University Clayton, VIC, Australia.
authors.forename: Gary F
authors.initials: GF
authors.lastname: Egan
keywords: CT reconstruction; Huntington's disease; Quantitative susceptibility mapping; cloud computing; digital atlasing; high performance computing; instrument integration; neuroinformatics infrastructure
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