title: α-Hydroxycyclopentanones via one-pot oxidation of the trimethylaluminum-mediated Nazarov reaction with triplet oxygen.
abstract: Trimethylaluminum and molecular oxygen are used in tandem to interrupt the Nazarov cyclization. α-Hydroxycyclopentanones are produced in moderate to good yield as a mixture of epimers. This sequence is the first example of combined nucleophilic/electrophilic trapping of the Nazarov oxyallyl intermediate.
authors.affiliation: Department of Chemistry, University of Alberta, E3-43 Gunning-Lemieux Chemistry Centre, Edmonton, AB, Canada. frederick.west@ualberta.ca.
authors.forename: Yonghoon
authors.initials: Y
authors.lastname: Kwon
authors.forename: Owen
authors.initials: O
authors.lastname: Scadeng
authors.forename: Robert
authors.initials: R
authors.lastname: McDonald
authors.forename: F G
authors.initials: FG
authors.lastname: West