title: A two-armed lanthanoid-chelating paramagnetic NMR probe linked to proteins via thioether linkages.
abstract: Paramagnetic NMR probes provide valuable long-range structural information on proteins and protein complexes. A new, stable, two-armed lanthanoid probe is reported that can be attached to a protein site-specifically via chemically inert thioether linkages.
authors.affiliation: Leiden Institute of Chemistry, Leiden University, Post Office Box 9502, 2300 RA Leiden (The Netherlands).
authors.forename: Wei-Min
authors.initials: WM
authors.lastname: Liu
authors.forename: Simon P
authors.initials: SP
authors.lastname: Skinner
authors.forename: Monika
authors.initials: M
authors.lastname: Timmer
authors.forename: Anneloes
authors.initials: A
authors.lastname: Blok
authors.forename: Mathias A S
authors.initials: MA
authors.lastname: Hass
authors.forename: Dmitri V
authors.initials: DV
authors.lastname: Filippov
authors.forename: Mark
authors.initials: M
authors.lastname: Overhand
authors.forename: Marcellus
authors.initials: M
authors.lastname: Ubbink
mesh_terms: D002614:Chelating Agents / Q000737:chemistry*; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: D002614:Chelating Agents; D028581:Lanthanoid Series Elements
keywords: lanthanides; paramagnetic NMR; protein modification; protein structures; pseudocontact shift