title: Biological consequences of zinc deficiency in the pathomechanisms of selected diseases.
abstract: From many points of view, zinc is one of the most important trace elements in biological systems. Many articles describe the well-known role of this metal in human physiology and pathophysiology, but in the related literature, there is a lack of current and reliable reviews of the role of zinc deficiency in many diseases. In this article, we describe the role of zinc deficiency in the oxidative stress control, immune response, proliferation, and pathogenesis and pathophysiology of selected diseases such as depression, cardiovascular diseases, diabetes mellitus, Alzheimer's disease, and Wilson's disease.
authors.affiliation: Department of Analytical Chemistry, Faculty of Chemistry, Jagiellonian University, R. Ingardena 3, 30-060, Kraków, Poland.
authors.forename: Kamil
authors.initials: K
authors.lastname: Jurowski
authors.forename: Bernadeta
authors.initials: B
authors.lastname: Szewczyk
authors.forename: Gabriel
authors.initials: G
authors.lastname: Nowak
authors.forename: Wojciech
authors.initials: W
authors.lastname: Piekoszewski
mesh_terms: D000544:Alzheimer Disease / Q000209:etiology / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000209:etiology / Q000378:metabolism*; D003866:Depressive Disorder / Q000209:etiology / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000209:etiology / Q000378:metabolism*; D006527:Hepatolenticular Degeneration / Q000209:etiology / Q000378:metabolism*; D006706:Homeostasis; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology / Q000378:metabolism*; D018384:Oxidative Stress; D015032:Zinc / Q000032:analysis / Q000172:deficiency* / Q000378:metabolism
chemical_list: D015032:Zinc
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