title: Oncolytic viruses targeting tumor stem cells.
abstract: A workshop "Targeting Oncolytic Viruses to Tumor Stem Cells," organized by the Division of Cancer Biology, NCI, NIH, was held on September 6, 2013 in Rockville, MD. Seventeen invited experts presented an overview of their current research in this area and discussed the state of current research on the use of oncolytic viruses targeted to stem cells as a potential cancer therapy. The goal was to evaluate the evidence that this approach might increase the efficacy of oncolytic virus therapy and to identify gaps in knowledge that have retarded progress in this area.
authors.affiliation: Authors' Affiliations: Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA and.
authors.forename: E Antonio
authors.initials: EA
authors.lastname: Chiocca
authors.affiliation: Division of Cancer Biology, National Cancer Institute, Bethesda, Maryland.
authors.forename: Donald
authors.initials: D
authors.lastname: Blair
authors.affiliation: Division of Cancer Biology, National Cancer Institute, Bethesda, Maryland mufsonr@mail.nih.gov.
authors.forename: R Allan
authors.initials: RA
authors.lastname: Mufson
mesh_terms: D005818:Genetic Engineering; D015316:Genetic Therapy / Q000379:methods; D006801:Humans; D058990:Molecular Targeted Therapy / Q000379:methods*; D009369:Neoplasms / Q000628:therapy*; D014411:Neoplastic Stem Cells; D050130:Oncolytic Virotherapy / Q000379:methods*; D050504:Oncolytic Viruses / Q000276:immunology*; D014779:Virus Replication