title: Acquisition of conditioned responding in a multiple schedule depends on the reinforcement's temporal contingency with each stimulus.
abstract: Forty mice acquired conditioned responses to stimuli presented in a multiple schedule with variable inter-trial intervals (ITIs). In some trials, reinforcement was preceded by a variable conditioned stimulus (CS), while other trials were reinforced following distinctive fixed-duration CS. A third stimulus was presented but never paired with reinforcement. Subjects in five groups experienced ITIs of different durations. Acquisition of responding to each stimulus depended only on the cycle-to-trial ratio (C/T), and thus on the temporal contingency of each stimulus. Acquisition was unaffected by whether CSs were of fixed or variable duration.
authors.affiliation: Molecular Genetics of Mental Retardation Unit, Department of Biotechnologies, Dulbecco Telethon Institute at the San Raffaele Scientific Institute, 20132 Milano, Italy.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Morè
authors.forename: Greg
authors.initials: G
authors.lastname: Jensen
mesh_terms: D000161:Acoustic Stimulation; D000704:Analysis of Variance; D000818:Animals; D001522:Behavior, Animal / Q000502:physiology*; D003214:Conditioning, Classical / Q000502:physiology*; D005508:Food Deprivation; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D012055:Reinforcement Schedule
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