title: Unilateral extrafoveal choroidal . ......... eovascularization in a 13-year-old child with bilateral optic nerve drusen.
abstract: OBJECTIVE
  The aim of our research was to describe the effect of an off-label intravitreal ranibizumab injection for treatment of unilateral extrafoveal choroidal neovascularization a with bilateral optic nerve drusen.
  
  
  METHODS
  13-year-old girl presented with decreased visual acuity of her left eye and optic nerve drusen confirmed by B-scan ultrasound examination in both eyes. Fluorescein angiography and optical coherence tomography revealed the presence of choroidal neovascularization in the left eye. The patient was treated with a single injection of ranibizumab and monitored by clinical examination, optical coherence tomography and fluorescein angiography.
  
  
  RESULTS
  Choroidal neovascularization was successfully treated and the best corrected visual acuity (Snellen) fully recovered from 20/50 to 20/20 over a period of 2 months. After this time at the 30 months follow-up, visual acuity and fundus were stable without the recurrence of choroidal neovascularization.
  
  
  CONCLUSIONS
  Optic nerve drusen should be taken into account and carefully observed as a possible cause of peripapillary choroidal neovascularization in children. Ranibizumab can be a successful off-label treatment in children suffering from choroidal neovascularization associated with optic nerve drusen.
authors.forename: Monika
authors.initials: M
authors.lastname: Jedrzejczak-Strózniak
authors.forename: Joanna
authors.initials: J
authors.lastname: Siwiec-Prościńska
authors.forename: Anna
authors.initials: A
authors.lastname: Gotz-Wieckowska
authors.forename: Jarosław
authors.initials: J
authors.lastname: Kociecki
mesh_terms: D000293:Adolescent; D061067:Antibodies, Monoclonal, Humanized / Q000008:administration & dosage*; D020256:Choroidal Neovascularization / Q000150:complications / Q000188:drug therapy*; D005260:Female; D006801:Humans; D058449:Intravitreal Injections; D056687:Off-Label Use; D015594:Optic Disk Drusen / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D000069579:Ranibizumab; D016896:Treatment Outcome
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D000069579:Ranibizumab