title: Psychostimulant addiction treatment.
abstract: Treatment of psychostimulant addiction has been a major, and not fully met, challenge. For opioid addiction, there is strong evidence for the effectiveness of several medications. For psychostimulants, there is no corresponding form of agonist maintenance that has met criteria for regulatory approval or generally accepted use. Stimulant-use disorders remain prevalent and can result in both short-term and long-term adverse consequences. The mainstay of treatment remains behavioral interventions. In this paper, we discuss those interventions and some promising candidates in the search for pharmacological interventions. This article is part of the Special Issue entitled 'CNS Stimulants'.
authors.affiliation: National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, MD, USA. Electronic address: phillipsk@nida.nih.gov.
authors.forename: Karran A
authors.initials: KA
authors.lastname: Phillips
authors.affiliation: National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, MD, USA.
authors.forename: David H
authors.initials: DH
authors.lastname: Epstein
authors.affiliation: National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, MD, USA.
authors.forename: Kenzie L
authors.initials: KL
authors.lastname: Preston
mesh_terms: D000697:Central Nervous System Stimulants / Q000008:administration & dosage* / Q000493:pharmacokinetics; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D012646:Self Administration; D013375:Substance Withdrawal Syndrome / Q000503:physiopathology / Q000628:therapy; D019966:Substance-Related Disorders / Q000503:physiopathology / Q000628:therapy*
chemical_list: D000697:Central Nervous System Stimulants
keywords: Addiction; Psychostimulant; Treatment
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