title: Mantle cell lymphoma and diffuse large B-cell lymphoma of the testis: a unique case of composite non-Hodgkin lymphoma.
abstract: Primary testicular non-Hodgkin lymphoma (NHL) is a rare entity with the most common histologic subtype consisting of diffuse large B-cell lymphoma (DLBCL). Patients with primary testicular lymphoma (PTL) have a poor prognosis and a higher propensity for relapse. Also rare are composite lymphomas (CL) defined as two or more morphologically and phenotypically distinct lymphomas coexisting in a single organ or tissue. Here we present the first reported case of primary testicular composite lymphoma consisting of DLBCL and mantle cell lymphoma (MCL).
authors.affiliation: Department of Medicine, Mayo Clinic, Jacksonville, FL, USA.
authors.forename: Swati
authors.initials: S
authors.lastname: Andhavarapu
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Crozier
authors.forename: Liuyan
authors.initials: L
authors.lastname: Jiang
authors.forename: Taimur
authors.initials: T
authors.lastname: Sher
mesh_terms: D000368:Aged; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D016130:Immunophenotyping; D017404:In Situ Hybridization, Fluorescence; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D020522:Lymphoma, Mantle-Cell / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D008297:Male; D049268:Positron-Emission Tomography; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: composite lymphoma; diffuse large b-cell lymphoma; mantle cell lymphoma; non-Hodgkin lymphoma; testicular lymphoma