title: Hidden progenitors replace microglia in the adult brain.
abstract: Microglia are highly dynamic components of the innate immune system. In this issue of Neuron, Elmore et al. (2014) report that global depletion of microglia triggers mobilization of latent microglial progenitors throughout the CNS, resulting in rapid repopulation.
authors.affiliation: Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 725 N. Wolfe Street, Baltimore, MD 21205, USA.
authors.forename: Ethan G
authors.initials: EG
authors.lastname: Hughes
authors.affiliation: Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 725 N. Wolfe Street, Baltimore, MD 21205, USA. Electronic address: dbergles@jhmi.edu.
authors.forename: Dwight E
authors.initials: DE
authors.lastname: Bergles
mesh_terms: D053687:Adult Stem Cells / Q000502:physiology*; D000818:Animals; D001921:Brain / Q000378:metabolism*; D008297:Male; D017628:Microglia / Q000378:metabolism*; D016186:Receptor, Macrophage Colony-Stimulating Factor / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*
chemical_list: D016186:Receptor, Macrophage Colony-Stimulating Factor