title: [A case of primary duodenal cancer recurrence successfully treated with CapeOX therapy].
abstract: A 55-year-old man was admitted to our hospital because of nausea and vomiting. An endoscopic examination and computed tomography(CT)scan revealed a duodenal tumor. A biopsy confirmed a diagnosis of primary duodenal adenocarcinoma. A pancreaticoduodenectomy and partial resection of the ascending colon were performed. Ten months after surgery, we observed lymph node recurrence and peritoneal dissemination. We then introduced capecitabine and oxaliplatin (CapeOX)therapy for treatment of the relapsed disease. A partial response(PR)was observed after 2 courses, and was sustained for 5 months. The patient survived another 1 year and 4 months after disease recurrence. CapeOX therapy can be an effective treatment for primary duodenal cancer.
authors.affiliation: Dept. of Surgery, Saitama Prefectural Cancer Center.
authors.forename: Masatake
authors.initials: M
authors.lastname: Miyamoto
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Kirii
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Takagi
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000601:surgery; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D000069287:Capecitabine; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D004379:Duodenal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D017809:Fatal Outcome; D005472:Fluorouracil / Q000008:administration & dosage / Q000031:analogs & derivatives; D006801:Humans; D008297:Male; D008875:Middle Aged; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D000077150:Oxaliplatin; D016577:Pancreaticoduodenectomy; D010534:Peritoneal Neoplasms / Q000188:drug therapy / Q000556:secondary; D012008:Recurrence
chemical_list: D009944:Organoplatinum Compounds; D000077150:Oxaliplatin; D003841:Deoxycytidine; D000069287:Capecitabine; D005472:Fluorouracil