title: Anorectal conditions: anal fissure and anorectal fistula.
abstract: Anal fissures are linear splits in the anal mucosa. Acute fissures typically resolve within a few weeks; chronic fissures persist longer than 8 to 12 weeks. Most fissures are posterior and midline and are related to constipation or anal trauma. Painful defecation and rectal bleeding are common symptoms. The diagnosis typically is clinical. High-fiber diet, stool softeners, and medicated ointments relieve symptoms and speed healing of acute fissures but offer limited benefit in chronic fissures. Lateral internal sphincterotomy is the surgical management of choice for chronic and refractory acute fissures. Anorectal fistula is an abnormal tract connecting the anorectal mucosa to the exterior skin. Fistulas typically develop after rupture or drainage of a perianal abscess. Fistulas are classified as simple or complex; low or high; and intersphincteric, transsphincteric, suprasphincteric, or extrasphincteric. Inspection of the perianal area identifies the skin opening, and anoscopy visualizes internal openings. The goal of management is to obliterate the tract and openings with negligible sphincter disruption to minimize incontinence. Fistulotomy is effective for simple fistulas; patients with complex fistulas may require fistulectomy. Other procedures that are used include injection of fibrin glue or insertion of a bioprosthetic plug into the fistula opening.
authors.affiliation: University of Oklahoma Department of Family and Preventive Medicine, 900 NE 10th St, Oklahoma City, OK 73104.
authors.forename: Audralan
authors.initials: A
authors.lastname: Fox
authors.affiliation: University of Oklahoma Department of Family and Preventive Medicine, 900 NE 10th St, Oklahoma City, OK 73104.
authors.forename: Pamela H
authors.initials: PH
authors.lastname: Tietze
authors.affiliation: University of Oklahoma Department of Family and Preventive Medicine, 900 NE 10th St, Oklahoma City, OK 73104, kramakrishnan@ouhsc.edu.
authors.forename: Kalyanakrishnan
authors.initials: K
authors.lastname: Ramakrishnan
mesh_terms: D005194:Family Practice; D005401:Fissure in Ano / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D054368:Laxatives; D012003:Rectal Fistula / Q000175:diagnosis / Q000628:therapy*; D012307:Risk Factors
chemical_list: D054368:Laxatives