title: A fatal case of peripartum cardiomyopathy.
abstract: Peripartum cardiomyopathy is a life-threatening cardiac condition affecting pregnant women either late in pregnancy or early in the post-partum period. The latest studies show a dramatic improvement in the mortality rates of women affected with this disorder, which has been correlated with advances in medical therapy for heart failure. However, patients continue to die of this condition. The following case report describes a typical patient with peripartum cardiomyopathy diagnosed on clinical grounds, along with echocardiogram findings of severe systolic dysfunction and global hypokinesis consistent with dilated cardiomyopathy. Emergency cesarean delivery had to be performed for fetal distress. There was significant improvement of the patient's condition with standard pharmacological management for heart failure at the time of discharge. However, five weeks after discharge, fatal cardiac arrest occurred. It is hoped that this article will raise awareness about this rare but potentially fatal condition and promote understanding of its main clinical features, diagnostic criteria, and conventional pharmacological management.
authors.affiliation: Division of Cardiology, Woodhull Medical Center , Brooklyn, NY . USA.
authors.forename: Ronny
authors.initials: R
authors.lastname: Cohen
authors.forename: Thierry
authors.initials: T
authors.lastname: Mallet
authors.forename: Brooks
authors.initials: B
authors.lastname: Mirrer
authors.forename: Pablo
authors.initials: P
authors.lastname: Loarte
authors.forename: Michael
authors.initials: M
authors.lastname: Gale
authors.forename: Paul
authors.initials: P
authors.lastname: Kastell
mesh_terms: D000328:Adult; D009202:Cardiomyopathies / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology; D002317:Cardiovascular Agents / Q000627:therapeutic use; D002585:Cesarean Section; D016757:Death, Sudden, Cardiac; D004638:Emergency Treatment; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D058725:Peripartum Period
chemical_list: D002317:Cardiovascular Agents