title: Evaluation of usefulness of hs-CRP and ferritin assays in patients with nasal polyps.
abstract: BACKGROUND
  Chronic nature of the nasal polyps, tendency to recurrence, and lack of satisfying treatment need the diagnostic's parameters which show early inflammatory state as ferritin and hs-CRP. The Aim of Study. Assessment of hs-CRP and ferritin blood levels in nasal polyps patients in evaluation of treatment efficacy.
  
  
  METHODS
  All 38 patients were divided into 2 groups. Group I included 19 patients with anti-inflammatory therapy 2 weeks after surgery. Group II included 19 patients without anti-inflammatory therapy 2 weeks after surgery. The levels of hs-CRP and ferritin have been assessed before and 2 and 6 weeks after surgical treatment.
  
  
  RESULTS
  Research showed statistically significant difference of ferritin's concentration between examined groups 6 weeks after surgery (P < 0.05) and statistically significant difference of hs-CRP concentration 2 and 6 weeks after surgery (P < 0.05).
  
  
  CONCLUSIONS
  (1) The analysis of serum ferritin and hs-CRP concentrations can be useful in early postoperative detection of inflammatory state in patients with nasal polyps and for the effectiveness of therapy. (2) Lack of correlation between mean ferritin and hs-CRP serum levels, at each diagnostic and monitoring stage, shows that they are independent and cannot be determined interchangeably.
authors.affiliation: Clinical Division of Anesthesiology and Intensive Treatment of the Department of Anesthesiology, Intensive Treatment and Emergency Medicine, Medical University of Silesia in Katowice, Plac Medyków 1, 41-200 Sosnowiec, Poland.
authors.forename: Robert
authors.initials: R
authors.lastname: Partyka
authors.affiliation: Clinical Division of Anesthesiology and Intensive Treatment of the Department of Anesthesiology, Intensive Treatment and Emergency Medicine, Medical University of Silesia in Katowice, Plac Medyków 1, 41-200 Sosnowiec, Poland.
authors.forename: Jacek
authors.initials: J
authors.lastname: Pałac
authors.affiliation: ENT Department in Zabrze, Medical University of Silesia, Katowice, Poland.
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Paluch
authors.affiliation: 3rd Department and Clinical Division of Cardiology SUM, Katowice, Poland.
authors.forename: Bożena
authors.initials: B
authors.lastname: Szyguła-Jurkiewicz
authors.affiliation: ENT Department in Zabrze, Medical University of Silesia, Katowice, Poland.
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Namysłowski
authors.affiliation: ENT Department in Zabrze, Medical University of Silesia, Katowice, Poland.
authors.forename: Maciej
authors.initials: M
authors.lastname: Misiołek
authors.affiliation: Clinical Division of Anesthesiology and Intensive Treatment of the Department of Anesthesiology, Intensive Treatment and Emergency Medicine, Medical University of Silesia in Katowice, Plac Medyków 1, 41-200 Sosnowiec, Poland.
authors.forename: Przemysław
authors.initials: P
authors.lastname: Jałowiecki
authors.affiliation: Clinical Division of Anesthesiology and Intensive Treatment of the Department of Anesthesiology, Intensive Treatment and Emergency Medicine, Medical University of Silesia in Katowice, Plac Medyków 1, 41-200 Sosnowiec, Poland.
authors.forename: Danuta
authors.initials: D
authors.lastname: Kokocińska
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000378:metabolism*; D005260:Female; D005293:Ferritins / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000097:blood* / Q000188:drug therapy / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D015415:Biomarkers; D002097:C-Reactive Protein; D005293:Ferritins
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