title: Microbial learning lessons: SFB educate the immune system.
abstract: Segmented filamentous bacteria (SFB) contribute to immune-system maturation. In this issue of Immunity, Goto et al. (2014) and Lécuyer et al. (2014) provide evidence for how SFB induce antigen-specific T helper 17 cells and promote development of adaptive immunity at discrete mucosal sites.
authors.affiliation: Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
authors.forename: Yun Kyung
authors.initials: YK
authors.lastname: Lee
authors.affiliation: Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: sarkis@caltech.edu.
authors.forename: Sarkis K
authors.initials: SK
authors.lastname: Mazmanian
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology*; D003013:Clostridium / Q000276:immunology*; D003015:Clostridium Infections / Q000276:immunology*; D003713:Dendritic Cells / Q000276:immunology*; D004926:Escherichia coli / Q000276:immunology*; D004927:Escherichia coli Infections / Q000276:immunology*; D000949:Histocompatibility Antigens Class II / Q000378:metabolism*; D007070:Immunoglobulin A / Q000378:metabolism*; D007422:Intestines / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology*; D010950:Plasma Cells / Q000276:immunology*; D058504:Th17 Cells / Q000276:immunology*
chemical_list: D000942:Antigens, Bacterial; D000949:Histocompatibility Antigens Class II; D007070:Immunoglobulin A