title: Aortic root rupture after TAVR in two renal transplant patients on chronic immunosuppressant therapy.
abstract: Patients on chronic immunosuppressant therapy after renal transplantation have a high rate of in-hospital mortality and approximately 20% mortality rate per year after conventional valve surgery. While transcatheter aortic valve replacement (TAVR) is an appealing option to consider for such patients, there are not significant outcome data for the procedure in this patient population. We report two cases of aortic root rupture after TAVR in renal transplant patients on chronic immunosuppressant therapy.
authors.affiliation: Medical City Hospital, Dallas, Texas; Cardiopulmonary Research Science and Technology Institute, Plano, Texas.
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Holper
authors.forename: Rebeca J
authors.initials: RJ
authors.lastname: Kim
authors.forename: Aaron
authors.initials: A
authors.lastname: Brooks
authors.forename: Michael
authors.initials: M
authors.lastname: Mack
mesh_terms: D000368:Aged; D001013:Aorta, Thoracic; D001019:Aortic Rupture / Q000175:diagnosis / Q000209:etiology*; D001024:Aortic Valve Stenosis / Q000150:complications / Q000601:surgery*; D017548:Echocardiography, Transesophageal; D017809:Fatal Outcome; D005260:Female; D006084:Graft Rejection / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation; D008875:Middle Aged; D061330:Multidetector Computed Tomography; D065467:Transcatheter Aortic Valve Replacement / Q000009:adverse effects*
chemical_list: D007166:Immunosuppressive Agents
keywords: TAVR; aortic rupture; renal transplant