title: Is pain the only symptom in patients with benign joint hypermobility syndrome?
abstract: The aims of this study were to evaluate pain, depression level, fatigue, sleep, and quality of life (QoL) among patients with benign joint hypermobility syndrome (BJHS) and to compare their results with those of healthy controls. The study involved 115 patients and 114 healthy volunteers. Pain level was rated using visual analogue scale (VAS) for all patients. Depression level, fatigue, sleep quality, and QoL of all the participants were evaluated by the Beck Depression Inventory (BDI), the Checklist Individual Strength (CIS), the Pittsburgh Sleep Quality Index (PSQI), and the Short Form-36 (SF-36), respectively. VAS value was 6.29 ± 0.94 in the patient group. Comparison of two groups showed that there were statistically significant differences between the patient group and the control group with respect to BDI, total CIS, PSQI scores, SF-36 subscales (physical function, role physical, bodily pain, general health, role emotional, and mental health), and mental component summary (p < 0.001). While pain is the predominant symptom among BJHS patients, depression, fatigue, impaired sleep, and QoL also commonly occur. Thus, all of these components should be taken into account when assessing patients with BJHS.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Medical School of Selcuk University, Konya, Turkey, ilknurftr@gmail.com.
authors.forename: İlknur
authors.initials: İ
authors.lastname: Albayrak
authors.forename: Halim
authors.initials: H
authors.lastname: Yilmaz
authors.forename: Halil Ekrem
authors.initials: HE
authors.lastname: Akkurt
authors.forename: Ali
authors.initials: A
authors.lastname: Salli
authors.forename: Gülten
authors.initials: G
authors.lastname: Karaca
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D003863:Depression / Q000523:psychology; D004535:Ehlers-Danlos Syndrome / Q000175:diagnosis* / Q000523:psychology*; D005221:Fatigue; D005260:Female; D006801:Humans; D007593:Joint Instability / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000209:etiology*; D010147:Pain Measurement; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life / Q000523:psychology; D012890:Sleep; D011795:Surveys and Questionnaires; D055815:Young Adult
references.citation: J Neurol Neurosurg Psychiatry. 2005 Oct;76(10):1406-9
references.pmid: 16170086
references.citation: Psychiatry Res. 1989 May;28(2):193-213
references.pmid: 2748771
references.citation: Psychiatry Res. 1988 Aug;25(2):213-22
references.pmid: 3051072
references.citation: Pediatr Rev. 1998 Apr;19(4):111-7
references.pmid: 9557061
references.citation: J Clin Nurs. 2007 Nov;16(11C):377-83
references.pmid: 17931330
references.citation: J Pain Symptom Manage. 1997 Aug;14(2):88-93
references.pmid: 9262038
references.citation: J Psychosom Res. 1994 Jul;38(5):383-92
references.pmid: 7965927
references.citation: Disabil Rehabil. 2010;32(16):1339-45
references.pmid: 20156051
references.citation: Semin Arthritis Rheum. 2010 Dec;40(3):267-74
references.pmid: 19878973
references.citation: Arthritis Rheum. 2004 Aug;50(8):2640-4
references.pmid: 15334479
references.citation: Physiother Theory Pract. 2012 Nov;28(8):624-32
references.pmid: 22324761
references.citation: Am J Med Genet A. 2009 Nov;149A(11):2368-70
references.pmid: 19842204
references.citation: Pain. 2007 Feb;127(3):243-252
references.pmid: 17055168
references.citation: Clin Orthop Relat Res. 1982 Aug;(168):124-7
references.pmid: 7105534
references.citation: Clin J Pain. 1997 Jun;13(2):116-37
references.pmid: 9186019
references.citation: Eur J Pain. 2006 May;10(4):287-333
references.pmid: 16095934
references.citation: Pediatrics. 2004 Apr;113(4):714-9
references.pmid: 15060217
references.citation: Lancet. 2004 Mar 20;363(9413):978-88
references.pmid: 15043967
references.citation: Am J Med Genet. 1994 Nov 1;53(2):149-52
references.pmid: 7856639
references.citation: Joint Bone Spine. 2000;67(3):157-63
references.pmid: 10875311
references.citation: Ann Neurol. 2010 Jan;67(1):145-6; author reply 146-7
references.pmid: 20186845
references.citation: Rheumatology (Oxford). 2001 May;40(5):485-7
references.pmid: 11371653
references.citation: Clin Exp Rheumatol. 2011 Nov-Dec;29(6):998-1005
references.pmid: 22208933
references.citation: Int J Psychiatry Med. 2011;41(2):187-201
references.pmid: 21675349
references.citation: Arthritis Rheum. 2004 Oct;50(10):3323-8
references.pmid: 15476239
references.citation: Int J Nurs Stud. 2000 Apr;37(2):111-8
references.pmid: 10684952
references.citation: Behav Res Ther. 1997 Aug;35(8):785-91
references.pmid: 9256522
references.citation: Clin Exp Rheumatol. 2004 Jul-Aug;22(4):495-8
references.pmid: 15301252
references.citation: Epidemiol Rev. 1995;17(1):139-51
references.pmid: 8521932
references.citation: Clin Genet. 2001 Nov;60(5):360-5
references.pmid: 11903337
references.citation: J Manipulative Physiol Ther. 2006 Jan;29(1):32-9
references.pmid: 16396727
references.citation: Arthritis Rheum. 2006 Feb;54(2):515-23
references.pmid: 16447226
references.citation: J Am Osteopath Assoc. 2006 Sep;106(9):531-6
references.pmid: 17079522
references.citation: Best Pract Res Clin Rheumatol. 2003 Dec;17(6):989-1004
references.pmid: 15123047
references.citation: Rheumatol Int. 2005 May;25(4):260-3
references.pmid: 14745505
references.citation: J Pain Symptom Manage. 2010 Sep;40(3):370-8
references.pmid: 20579833
references.citation: Psychosomatics. 2004 Sep-Oct;45(5):432-7
references.pmid: 15345789
references.citation: Ann Rheum Dis. 1973 Sep;32(5):413-8
references.pmid: 4751776
references.citation: Rheumatol Int. 2011 Sep;31(9):1131-6
references.pmid: 21373784
references.citation: Am J Psychiatry. 1998 Nov;155(11):1578-83
references.pmid: 9812121