title: Predictive saccade target selection in superior colliculus during visual search.
abstract: Searching for a visual object naturally involves sequences of gaze fixations, during which the current foveal image is analyzed and the next object to inspect is selected as a saccade target. Fixation durations during such sequences are short, suggesting that saccades may be concurrently processed. Therefore, the selection of the next saccade target may occur before the current saccade target is acquired. To test this hypothesis, we trained four female rhesus monkeys (Macaca mulatta) to perform a multiple-fixation visual conjunction search task. We simultaneously recorded the activity of sensorimotor neurons in the midbrain superior colliculus (SC) in two monkeys. In this task, monkeys made multiple fixations before foveating the target. Fixation durations were significantly shorter than the latency of the initial responses to the search display, with approximately one-quarter being shorter than the shortest response latencies. The time at which SC sensorimotor activity discriminated the target from distracters occurred significantly earlier for the selection of subsequent fixations than for the selection of the first fixation. Target selection during subsequent fixations occurred even before the visual afferent delay in more than half of the neuronal sample, suggesting that the process of selection can encompass at least two future saccade targets. This predictive selection was present even when differences in saccade latencies were taken into account. Altogether, these findings demonstrate how neural representations on the visual salience map are processed in parallel, thus facilitating visual search.
authors.affiliation: Centre for Neuroscience Studies and Departments of Biomedical and Molecular Sciences and Psychology, Queen's University, Kingston, Ontario, Canada K7L 3N6.
authors.forename: Kelly
authors.initials: K
authors.lastname: Shen
authors.forename: Martin
authors.initials: M
authors.lastname: Paré
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001288:Attention / Q000502:physiology*; D002755:Choice Behavior / Q000502:physiology*; D005260:Female; D005403:Fixation, Ocular / Q000502:physiology*; D008253:Macaca mulatta; D009474:Neurons / Q000502:physiology; D010775:Photic Stimulation; D011237:Predictive Value of Tests; D012372:ROC Curve; D011930:Reaction Time; D012438:Saccades / Q000502:physiology*; D017603:Signal Detection, Psychological; D013477:Superior Colliculi / Q000166:cytology / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*
keywords: concurrent processing; monkey; saccade target selection; visual search
references.citation: J Neurophysiol. 1997 Sep;78(3):1373-83
references.pmid: 9310428
references.citation: J Exp Psychol Hum Percept Perform. 1982 Feb;8(1):113-26
references.pmid: 6460077
references.citation: J Neurophysiol. 1995 May;73(5):1988-2003
references.pmid: 7623096
references.citation: Percept Psychophys. 1996 Oct;58(7):969-76
references.pmid: 8920834
references.citation: Vision Res. 2000;40(18):2499-516
references.pmid: 10915889
references.citation: J Exp Psychol Hum Percept Perform. 2006 Apr;32(2):235-50
references.pmid: 16634668
references.citation: Nature. 1998 Jan 29;391(6666):481-4
references.pmid: 9461214
references.citation: J Neurosci. 2006 Apr 5;26(14):3656-61
references.pmid: 16597719
references.citation: J Exp Psychol Hum Percept Perform. 2002 Oct;28(5):1039-54
references.pmid: 12421054
references.citation: J Exp Psychol Hum Percept Perform. 2003 Oct;29(5):882-96
references.pmid: 14585012
references.citation: Eur J Neurosci. 2011 Jun;33(11):2003-16
references.pmid: 21645096
references.citation: Vision Res. 1987;27(8):1327-41
references.pmid: 3424681
references.citation: J Neurophysiol. 2001 Jun;85(6):2545-62
references.pmid: 11387400
references.citation: J Neurophysiol. 2007 Feb;97(2):1457-69
references.pmid: 17135479
references.citation: Annu Rev Neurosci. 2008;31:317-38
references.pmid: 18558858
references.citation: J Neurophysiol. 2005 Jan;93(1):337-51
references.pmid: 15317836
references.citation: Annu Rev Psychol. 1999;50:243-71
references.pmid: 10074679
references.citation: J Neurophysiol. 2002 Oct;88(4):2019-34
references.pmid: 12364525
references.citation: Neuroreport. 2007 Aug 6;18(12):1207-13
references.pmid: 17632269
references.citation: J Neurophysiol. 1996 Dec;76(6):4040-55
references.pmid: 8985899
references.citation: Science. 2007 Mar 30;315(5820):1860-2
references.pmid: 17395832
references.citation: Vision Res. 2001 Mar;41(6):785-800
references.pmid: 11248266
references.citation: J Neurophysiol. 2006 May;95(5):2845-55
references.pmid: 16467428
references.citation: J Neurosci. 2001 Feb 15;21(4):1340-50
references.pmid: 11160405
references.citation: Science. 2007 Oct 5;318(5847):44; author reply 44
references.pmid: 17916712
references.citation: Vision Res. 1998 Jun;38(12):1805-15
references.pmid: 9797959
references.citation: J Vis. 2010 Dec 29;10(14):
references.pmid: 21191134
references.citation: J Neurophysiol. 2006 Jun;95(6):3502-11
references.pmid: 16641382
references.citation: Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):13086-90
references.pmid: 15326284
references.citation: Front Hum Neurosci. 2010 Apr 13;4:31
references.pmid: 20428512
references.citation: J Integr Neurosci. 2009 Jun;8(2):137-74
references.pmid: 19618485
references.citation: Vision Res. 2001 Jan;41(1):87-95
references.pmid: 11163618
references.citation: Vision Res. 1997 Oct;37(19):2745-56
references.pmid: 9373673
references.citation: J Neurophysiol. 2007 Jan;97(1):942-7
references.pmid: 17079346
references.citation: Proc Biol Sci. 2002 Aug 7;269(1500):1571-9
references.pmid: 12184827
references.citation: Science. 2005 Apr 22;308(5721):529-34
references.pmid: 15845848
references.citation: Vision Res. 1984;24(5):429-48
references.pmid: 6740964
references.citation: Psychol Sci. 2014 Jan;25(1):215-23
references.pmid: 24166857
references.citation: Vision Res. 1979;19(9):967-83
references.pmid: 532123
references.citation: Exp Brain Res. 2008 Jan;184(3):411-25
references.pmid: 17846754
references.citation: Science. 1992 Jan 3;255(5040):90-2
references.pmid: 1553535
references.citation: J Neurophysiol. 2002 Apr;87(4):1805-15
references.pmid: 11929902
references.citation: Exp Brain Res. 1987;66(3):465-78
references.pmid: 3609194
references.citation: Trends Cogn Sci. 2003 Nov;7(11):498-504
references.pmid: 14585447
references.citation: Neuron. 2001 May;30(2):583-91
references.pmid: 11395016
references.citation: J Neurosci. 2011 Aug 24;31(34):12307-17
references.pmid: 21865473
references.citation: J Vis. 2007 Nov 23;7(5):15.1-13
references.pmid: 18217855
references.citation: Neuron. 2011 Jun 23;70(6):1205-17
references.pmid: 21689605
references.citation: Psychol Bull. 1998 Nov;124(3):372-422
references.pmid: 9849112
references.citation: Vision Res. 2009 Jun;49(10):1256-66
references.pmid: 18226827
references.citation: Invest Ophthalmol. 1975 Apr;14(4):317-21
references.pmid: 1123288
references.citation: J Neurophysiol. 2010 Mar;103(3):1238-52
references.pmid: 20018833
references.citation: J Neurophysiol. 2011 Oct;106(4):1862-74
references.pmid: 21753030