title: Sex differences in human epilepsy.
abstract: In the majority of neuropsychiatric conditions, marked gender-based differences have been found in the epidemiology, clinical manifestations, and therapy of disease. Emerging data suggest that gender differences exist also in the epidemiology, and pathophysiology of epilepsy. The present review summarizes the current information regarding gender and epilepsy. These differences are regarded from the perspective of innate sex differences in cerebral morphology, structural and functional connections, and assuming that these differences may render men and women differently vulnerable to epileptogenicity.
authors.affiliation: Karolinska Institute, Department of Women's, Children's Health, Neurology Clinic Karolinska Hospital, Q2:07, SE-171 76 Stockholm, Sweden. Electronic address: ivanka.savic-berglund@ki.se.
authors.forename: Ivanka
authors.initials: I
authors.lastname: Savic
mesh_terms: D001921:Brain / Q000473:pathology; D004827:Epilepsy / Q000150:complications / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy*; D004829:Epilepsy, Generalized / Q000453:epidemiology / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000150:complications / Q000453:epidemiology / Q000473:pathology; D009420:Nervous System / Q000473:pathology; D012727:Sex Characteristics
keywords: Brain; Epilepsy; MRI; MTLE; Sex difference