title: Developments in the field of bioorthogonal bond forming reactions-past and present trends.
abstract: In response to the ever increasing need of chemical biology for new tools, a wide variety of new, highly selective reactions have been described. Herein we report a summary of recent developments and the historical background on bioorthogonal ligation reactions.
authors.affiliation: Laboratory of Functional Chemo-Systems (UMR 7199), Labex Medalis, University of Strasbourg - CNRS , 74 Route du Rhin, BP 60024, 67401 Illkirch-Graffenstaden, France.
authors.forename: Mathias
authors.initials: M
authors.lastname: King
authors.forename: Alain
authors.initials: A
authors.lastname: Wagner
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D000480:Alkynes / Q000138:chemical synthesis* / Q000737:chemistry; D000818:Animals; D006801:Humans; D008958:Models, Molecular; D015394:Molecular Structure
chemical_list: D000475:Alkenes; D000480:Alkynes