title: [Cortisol levels in cord blood with various violations of neonatal adaptation].
abstract: Shifting extra uterine existence is a serious test of maturity of all functional systems of the newborn, so in recent years, the more attention is payed for the adaptation of the newborn. It is known that the pathological course of pregnancy is a violation of the functional state of the adrenal cortex, and prolonged exposure of the pathological factor leads to the inhibition of adrenocortical function and a decrease of the adaptive capabilities of a newborn. Therefore, serum cortisol levels could be a predictor of complications in preterm infants. Based on this, it seems appropriate to study changes in the content of serum cortisol cord blood prior to the development of various syndromes neonatal maladjustment. The clinical and laboratory examination of term infants with various disorders of adaptation: regurgitation, pain, hyperexcitability , depression, cardio-respiratory depression, bleeding in the skin, toxic erythema. It is shown that the most prominent violations maladjustment processes occur on the background of decreased cortisol. Border states, which are formed on the background of normal or elevated cortisol, are not accompanied by significant impairments of adaptation processes. On the basis of the data was drawn a conclusion about the possibility of using changes of cortisol in cord blood as a reliable indicator of neonatal adaptation processes, pointing to the possibility of the development of pathological conditions.
authors.forename: L I
authors.initials: LI
authors.lastname: Kolesnikova
authors.forename: A S
authors.initials: AS
authors.lastname: Popova
authors.forename: A I
authors.initials: AI
authors.lastname: Sinitskiĭ
authors.forename: D A
authors.initials: DA
authors.lastname: Kozochkin
authors.forename: A B
authors.initials: AB
authors.lastname: Gornostaeva
mesh_terms: D000222:Adaptation, Physiological; D000302:Adrenal Cortex / Q000378:metabolism / Q000503:physiopathology; D005260:Female; D005312:Fetal Blood; D005333:Fetus / Q000378:metabolism / Q000503:physiopathology; D005865:Gestational Age; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis / Q000097:blood; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000378:metabolism / Q000503:physiopathology; D008297:Male; D011247:Pregnancy; D015203:Reproducibility of Results
chemical_list: D006854:Hydrocortisone