title: Rapidly progressive cognitive impairment in a patient with high flow dural arteriovenous fistulas, cerebral sinus thrombosis and protein S deficiency.
abstract: Dural arteriovenous fistula (DAVF) may present with a variety of neurological symptoms, ranging from tinnitus to fatal hemorrhage. We report a case of rapidly progressive cognitive impairment due to cerebral venous engorgement that reversed after endovascular treatment in a patient with DAVF, cerebral sinus thrombosis and protein S deficiency. DAVF may be a cause of vascular cognitive impairment and should be considered particularly in cases with a rapidly progressive course because they are potentially treatable.
authors.affiliation: NEUROFARBA Department, Neuroscience Section, University of Florence, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Pasi
authors.affiliation: Interventional Neuroradiology Unit, Azienda Ospedaliero Universitaria Careggi, Florence, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Nappini
authors.affiliation: NEUROFARBA Department, Neuroscience Section, University of Florence, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Salvadori
authors.affiliation: Interventional Neuroradiology Unit, Azienda Ospedaliero Universitaria Careggi, Florence, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Mangiafico
authors.affiliation: Interventional Neuroradiology Unit, Azienda Ospedaliero Universitaria Careggi, Florence, Italy.
authors.forename: N
authors.initials: N
authors.lastname: Limbucci
authors.affiliation: Stroke Unit and Neurology, Azienda Ospedaliero Universitara Careggi, Largo Brambilla 3, 50134 Firenze, Italy. Electronic address: pantoni@unifi.it.
authors.forename: L
authors.initials: L
authors.lastname: Pantoni
mesh_terms: D000368:Aged; D015901:Angiography, Digital Subtraction; D001921:Brain / Q000473:pathology; D020785:Central Nervous System Vascular Malformations / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy*; D002533:Cerebral Angiography; D003072:Cognition Disorders / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy; D018450:Disease Progression; D004621:Embolization, Therapeutic; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009483:Neuropsychological Tests; D018455:Protein S Deficiency / Q000473:pathology / Q000503:physiopathology*; D012851:Sinus Thrombosis, Intracranial / Q000473:pathology / Q000503:physiopathology*
keywords: Angiographic procedure; Cognitive impairment; Dural arteriovenous fistula; Neuropsychological evaluation; Vascular dementia