title: Isolation, structure and bioactivities of the polysaccharides from Angelica sinensis (Oliv.) Diels: a review.
abstract: The root of Angelica sinensis (Oliv.) Diels, a well-known Chinese herbal medicine, has been used historically as a tonic, hematopoietic and anti-inflammatory agent for thousands of years. Modern phytochemistry and pharmacological experiments have proved that polysaccharide is one of the major active ingredients in A. sinensis. It has been demonstrated that A. sinensis polysaccharides had various important biological activities, such as hematopoiesis, immunomodulation, antitumor, antioxidant, radioprotection and hypoglycemic activity. The purpose of the present review is to summarize previous and current references regarding extraction and purification techniques as well as structural characterization and biological activities of A. sinensis polysaccharides.
authors.affiliation: Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical University, 127 Youyi Xilu, Xi'an 710072, PR China.
authors.forename: Mingliang
authors.initials: M
authors.lastname: Jin
authors.affiliation: College of Medicine, Xi'an Jiaotong University, No. 76 Yanta West Road, Xi'an 710061, PR China.
authors.forename: Ke
authors.initials: K
authors.lastname: Zhao
authors.affiliation: Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical University, 127 Youyi Xilu, Xi'an 710072, PR China.
authors.forename: Qingsheng
authors.initials: Q
authors.lastname: Huang
authors.affiliation: Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical University, 127 Youyi Xilu, Xi'an 710072, PR China.
authors.forename: Chunlan
authors.initials: C
authors.lastname: Xu
authors.affiliation: Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical University, 127 Youyi Xilu, Xi'an 710072, PR China.
authors.forename: Peng
authors.initials: P
authors.lastname: Shang
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology; D029971:Angelica sinensis / Q000737:chemistry*; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology; D000975:Antioxidants / Q000494:pharmacology; D041981:Gastrointestinal Tract / Q000187:drug effects; D006410:Hematopoiesis / Q000187:drug effects; D006801:Humans; D007004:Hypoglycemic Agents / Q000494:pharmacology; D015394:Molecular Structure; D011134:Polysaccharides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D011837:Radiation-Protective Agents / Q000494:pharmacology
chemical_list: D000276:Adjuvants, Immunologic; D000972:Antineoplastic Agents, Phytogenic; D000975:Antioxidants; D007004:Hypoglycemic Agents; D011134:Polysaccharides; D011837:Radiation-Protective Agents