title: Mammographic and clinicopathological features of triple-negative breast cancer.
abstract: OBJECTIVE
  Triple-negative breast cancer (TNBC) lacks effective treatment and has a poor prognosis. This study assessed mammographic findings and clinicopathological features of TNBC by comparing with non-TNBC in order to improve clinical diagnosis of TNBC.
  
  
  METHODS
  A total of 426 patients with pathologically confirmed breast cancer were retrospectively assigned into two groups, TNBC (n = 54) and non-TNBC (n = 372), and then analysed.
  
  
  RESULTS
  TNBC frequently showed a high histological grade, presented with a mass (79.6%) and was less frequently associated with focal asymmetric density (11.1%), microcalcifications (5.6%) and distortion (3.7%) on mammography. TNBC mammographic masses were most frequently round/oval (58.1%) or lobular (30.2%) in shape and were less frequently irregular in shape (11.6%). Masses with circumscribed margins were the most frequent (37.2%), with microlobulated (25.6%) and obscured (16.3%) margins being commonly observed, but masses with spiculated margins were rare (9.3%).
  
  
  CONCLUSIONS
  TNBC could have distinct mammographic and clinicopathological features compared with non-TNBC, and thus mammography may be useful in the diagnosis of TNBC.
  
  
  CONCLUSIONS
  This study demonstrated distinct mammographic and clinicopathological features to help in diagnosis of Chinese patients with TNBC.
authors.affiliation: 1 Department of Radiology, The Second Affiliated Hospital, Harbin Medical University, Harbin, China.
authors.forename: B
authors.initials: B
authors.lastname: Gao
authors.forename: H
authors.initials: H
authors.lastname: Zhang
authors.forename: S-D
authors.initials: SD
authors.lastname: Zhang
authors.forename: X-Y
authors.initials: XY
authors.lastname: Cheng
authors.forename: S-M
authors.initials: SM
authors.lastname: Zheng
authors.forename: Y-H
authors.initials: YH
authors.lastname: Sun
authors.forename: D-W
authors.initials: DW
authors.lastname: Zhang
authors.forename: Y
authors.initials: Y
authors.lastname: Jiang
authors.forename: J-W
authors.initials: JW
authors.lastname: Tian
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D060787:Neoplasm Grading; D012189:Retrospective Studies; D064726:Triple Negative Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*
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