title: HIV and schistosomiasis co-infection in African children.
abstract: HIV/AIDS and schistosomiasis both cause a substantial disease burden in sub-Saharan Africa and the two diseases often overlap in their epidemiological characteristics. Although disease-specific control interventions are continuing, potential synergies in the control efforts for these two diseases have not been investigated. With a focus on children with schistosomiasis, we assess the risk for increased HIV transmission, HIV progression, and impaired response to drugs when given alongside HIV interventions. A new research agenda tailored to children is needed to better understand the interactions of these two diseases and the potential for combined responses.
authors.affiliation: Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, UK.
authors.forename: Amaya
authors.initials: A
authors.lastname: Bustinduy
authors.affiliation: Center for Global Health and Diseases, Case Western Reserve University, Cleveland, OH, USA.
authors.forename: Charles
authors.initials: C
authors.lastname: King
authors.affiliation: Liverpool Pharmacometrics Group, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
authors.forename: Janet
authors.initials: J
authors.lastname: Scott
authors.affiliation: School of Clinical Medicine, University of Cambridge, Cambridge, UK.
authors.forename: Sarah
authors.initials: S
authors.lastname: Appleton
authors.affiliation: Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, UK.
authors.forename: José Carlos
authors.initials: JC
authors.lastname: Sousa-Figueiredo
authors.affiliation: Department of Production and Population Health, Royal Veterinary College, Hatfield, UK.
authors.forename: Martha
authors.initials: M
authors.lastname: Betson
authors.affiliation: Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, UK. Electronic address: jrstoth@liverpool.ac.uk.
authors.forename: J Russell
authors.initials: JR
authors.lastname: Stothard
mesh_terms: D000349:Africa / Q000453:epidemiology; D002648:Child; D060085:Coinfection / Q000453:epidemiology / Q000469:parasitology* / Q000517:prevention & control / Q000821:virology*; D015658:HIV Infections / Q000453:epidemiology / Q000469:parasitology* / Q000517:prevention & control; D006801:Humans; D012307:Risk Factors; D012552:Schistosomiasis / Q000453:epidemiology / Q000469:parasitology / Q000517:prevention & control / Q000821:virology*