title: Bioconjugations of polyethylenimine-capped LaF3:Ce, Tb nanoparticles with bovine serum albumin and photoluminescent properties.
abstract: Water-soluble Ce3+ and Tb3+ co-doped LaF3 nanoparticles with surfaces functionalized by a layer of polyethylenimine (PEI) were synthesized via a facile one-step hydrothermal method. Bovine serum albumin (BSA) protein was conjugated with LaF3:Ce, Tb nanoparticles via free amino groups on the surfaces of the nanocrystals. The final products were characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), ultraviolet (UV) spectrophotometry, and photoluminescence (PL) spectroscopy. XRD results showed that pure hexagonal phase LaF3:Ce, Tb nanoparticles could be obtained via a PEI assisted hydrothermal process at 180 degrees C for 24 h. The FE-SEM results showed that the morphology of pure LaF3:Ce, Tb nanoparticles was spherical with an average diameter of -20 nm. The UV spectra showed that BSA had been conjugated with LaF3:Ce, Tb nanoparticles. The photoluminescent (PL) properties of LaF3:Ce, Tb nanoparticles were also studied. The strong green emission of Tb3+ in LaF3:Ce, Tb nanoparticles suggests that these nanoparticles may have potential applications for labels in biological imaging and immunoassays.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Ruinian
authors.initials: R
authors.lastname: Hua
authors.forename: Wanyue
authors.initials: W
authors.lastname: Shao
authors.forename: Jun
authors.initials: J
authors.lastname: Zhao
authors.forename: Liyan
authors.initials: L
authors.lastname: Na
mesh_terms: D002563:Cerium / Q000737:chemistry*; D005459:Fluorides / Q000737:chemistry*; D007811:Lanthanum / Q000737:chemistry*; D049449:Luminescence; D053768:Metal Nanoparticles; D008855:Microscopy, Electron, Scanning; D011094:Polyethyleneimine / Q000737:chemistry*; D012710:Serum Albumin, Bovine / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D013725:Terbium / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D013725:Terbium; C083668:lanthanum trifluoride; D012710:Serum Albumin, Bovine; D002563:Cerium; D007811:Lanthanum; D011094:Polyethyleneimine; D005459:Fluorides