title: Preparation methods of alginate nanoparticles.
abstract: This article reviews available methods for the formation of alginate nano-aggregates, nanocapsules and nanospheres. Primarily, alginate nanoparticles are being prepared by two methods. In the "complexation method", complex formation on the interface of an oil droplet is used to form alginate nanocapsules, and complex formation in an aqueous solution is used to form alginate nano-aggregates. In a second method w/o emulsification coupled with gelation of the alginate emulsion droplet can be used to form alginate nanospheres. We review advantages and disadvantages of these methods, and give an overview of the properties of the alginate particles produced with these methods.
authors.affiliation: Laboratory of Organic Chemistry, Wageningen University, Dreijenplein 8, 6703 HB Wageningen, The Netherlands; Laboratory of Physics and Physical Chemistry of Foods, Wageningen University, Bornse Weilanden 9, 6708 WG Wageningen, The Netherlands.
authors.forename: Jerome P
authors.initials: JP
authors.lastname: Paques
authors.affiliation: Laboratory of Physics and Physical Chemistry of Foods, Wageningen University, Bornse Weilanden 9, 6708 WG Wageningen, The Netherlands.
authors.forename: Erik
authors.initials: E
authors.lastname: van der Linden
authors.affiliation: Laboratory of Organic Chemistry, Wageningen University, Dreijenplein 8, 6703 HB Wageningen, The Netherlands.
authors.forename: Cees J M
authors.initials: CJ
authors.lastname: van Rijn
authors.affiliation: Laboratory of Physics and Physical Chemistry of Foods, Wageningen University, Bornse Weilanden 9, 6708 WG Wageningen, The Netherlands. Electronic address: leonard.sagis@wur.nl.
authors.forename: Leonard M C
authors.initials: LM
authors.lastname: Sagis
keywords: Alginate; Nano-aggregates; Nanobeads; Nanocapsules; Nanoparticles; Nanospheres