title: Treatment of Laryngoceles: what is the progress over the last two decades?
abstract: OBJECTIVE
  To review surgical techniques used in the treatment of laryngoceles over the last two decades and point out developments and trends.
  
  
  METHODS
  PubMed, the Cochrane Library, and the JBI Library of Systematic Reviews were searched using the term "laryngocele." Demographic data, type of laryngocele, presence of a laryngopyocele, type of treatment and need for a tracheotomy were assessed.
  
  
  RESULTS
  Overall, data on 86 patients were analyzed, culled from 50 articles, of which 41 were case reports and 9 were case series. No single systematic review or meta-analysis or randomized controlled trial has been published on the topic. Altogether, 71 laryngoceles in 63 patients met the criteria for further analysis focusing on surgical treatment. An external approach was selected in 25/29 (86.2%) cases of combined laryngoceles. Microlaryngoscopic resection using a CO2 laser was performed in three cases and endoscopic robotic surgery in one case. The majority of patients with an internal laryngocele, 31/42 (73.8%), were treated using the microlaryngoscopy approach.
  
  
  CONCLUSIONS
  Microlaryngoscopy involving the use of a CO2 laser has become the main therapeutic procedure for the treatment of internal laryngoceles during the past 20 years. An external approach still remains the main therapeutic approach for the treatment of combined laryngoceles.
authors.affiliation: Department of Otorhinolaryngology, University Hospital Ostrava, 17. listopadu 1790, 708 52 Ostrava, Czech Republic.
authors.forename: Karol
authors.identifier: 0000-0003-1349-9958
authors.initials: K
authors.lastname: Zelenik
authors.affiliation: Department of Otorhinolaryngology, University Hospital Ostrava, 17. listopadu 1790, 708 52 Ostrava, Czech Republic.
authors.forename: Lucia
authors.identifier: 0000-0002-8796-7366
authors.initials: L
authors.lastname: Stanikova
authors.affiliation: Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine in Hradec Kralove,University Hospital Hradec Kralove, Charles University in Prague, Sokolska 581, 50 005 Hradec Kralove, Czech Republic.
authors.forename: Katarina
authors.identifier: 0000-0002-2953-5290
authors.initials: K
authors.lastname: Smatanova
authors.affiliation: Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine in Hradec Kralove,University Hospital Hradec Kralove, Charles University in Prague, Sokolska 581, 50 005 Hradec Kralove, Czech Republic.
authors.forename: Michal
authors.initials: M
authors.lastname: Cerny
authors.affiliation: Department of Otorhinolaryngology, University Hospital Ostrava, 17. listopadu 1790, 708 52 Ostrava, Czech Republic.
authors.forename: Pavel
authors.identifier: 0000-0001-6238-0756
authors.initials: P
authors.lastname: Kominek
mesh_terms: D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D059608:Laryngocele / Q000266:history / Q000601:surgery*; D007828:Laryngoscopy / Q000266:history / Q000379:methods*; D053685:Laser Therapy / Q000266:history / Q000379:methods*; D039781:PubMed; D065287:Robotic Surgical Procedures / Q000266:history / Q000379:methods*
references.citation: Eur Arch Otorhinolaryngol. 2005 Jun;262(6):473-6
references.pmid: 15549338
references.citation: J Otolaryngol. 1977 Jun;6(3):191-9
references.pmid: 894767
references.citation: Neuroradiology. 1998 Jun;40(6):401-3
references.pmid: 9689634
references.citation: Laryngoscope. 2010;120 Suppl 4:S189
references.pmid: 21225787
references.citation: Eur Arch Otorhinolaryngol. 2004 Jul;261(6):307-9
references.pmid: 14551785
references.citation: Eur Arch Otorhinolaryngol. 2001 Mar;258(3):137-40
references.pmid: 11374255
references.citation: J Laryngol Otol. 1999 Apr;113(4):361-3
references.pmid: 10474675
references.citation: Indian J Otolaryngol Head Neck Surg. 1998 Jul;50(3):298-301
references.pmid: 23119442
references.citation: Laryngoscope. 1991 May;101(5):529-36
references.pmid: 2030634
references.citation: Eur Arch Otorhinolaryngol. 2000 Nov;257(9):507-11
references.pmid: 11131379
references.citation: Case Rep Surg. 2011;2011:873613
references.pmid: 22606596
references.citation: AJNR Am J Neuroradiol. 2013 Apr;34(4):E39-42
references.pmid: 22173772
references.citation: ORL J Otorhinolaryngol Relat Spec. 2001 Jan-Feb;63(1):58-60
references.pmid: 11174065
references.citation: Ann Otol Rhinol Laryngol. 1997 Jul;106(7 Pt 1):556-9
references.pmid: 9228854
references.citation: Otolaryngol Head Neck Surg. 2001 Oct;125(4):370-3
references.pmid: 11593174
references.citation: J Laryngol Otol. 2001 Jul;115(7):590-2
references.pmid: 11485599
references.citation: Rom J Morphol Embryol. 2011;52(1):183-5
references.pmid: 21424053
references.citation: Sleep Breath. 2009 Aug;13(3):285-7
references.pmid: 19288148
references.citation: Arch Otolaryngol. 1966 Mar;83(3):270-5
references.pmid: 5904050
references.citation: J Laryngol Otol. 2013 Apr;127(4):435-7
references.pmid: 23448379
references.citation: Ear Nose Throat J. 1994 Apr;73(4):258-61
references.pmid: 8020424
references.citation: Auris Nasus Larynx. 2003 May;30(2):197-200
references.pmid: 12753994
references.citation: Auris Nasus Larynx. 2010 Feb;37(1):117-20
references.pmid: 19410402
references.citation: Forensic Sci Int. 2009 Sep 10;190(1-3):e1-4
references.pmid: 19500925
references.citation: Acta Otorhinolaryngol Ital. 2011 Apr;31(2):113-7
references.pmid: 22064820
references.citation: Braz J Otorhinolaryngol. 2008 Jan-Feb;74(1):143-6
references.pmid: 18392516
references.citation: Am J Otolaryngol. 2013 Nov-Dec;34(6):746-8
references.pmid: 24028977
references.citation: Indian J Otolaryngol Head Neck Surg. 2008 Dec;60(4):303-8
references.pmid: 23120570
references.citation: BMC Surg. 2006 Nov 27;6:14
references.pmid: 17129390
references.citation: Laryngoscope. 2000 Mar;110(3 Pt 1):447-50
references.pmid: 10718436
references.citation: Indian J Otolaryngol Head Neck Surg. 2012 Jun;64(2):193-6
references.pmid: 23730585
references.citation: Eur J Radiol. 2000 Jan;33(1):63-5
references.pmid: 10674793
references.citation: J Voice. 2011 May;25(3):272-4
references.pmid: 20430574
references.citation: Laryngoscope. 1974 Aug;84(8):1291-6
references.pmid: 4414058
references.citation: Otolaryngol Head Neck Surg. 2007 Feb;136(2):211-5
references.pmid: 17275541
references.citation: Wien Klin Wochenschr. 2005 Oct;117(19-20):718-20
references.pmid: 16416373
references.citation: J Voice. 2002 Jun;16(2):258-66
references.pmid: 12150378
references.citation: J Res Med Sci. 2013 May;18(5):453-6
references.pmid: 24174956
references.citation: Acta Otorhinolaryngol Ital. 2007 Oct;27(5):255-7
references.pmid: 18198756
references.citation: Clin Imaging. 2002 Mar-Apr;26(2):86-8
references.pmid: 11852212
references.citation: J Otolaryngol. 2007 Jun;36(3):E5-8
references.pmid: 17711764
references.citation: BMJ Case Rep. 2010 Nov 26;2010:
references.pmid: 22797479
references.citation: Leg Med (Tokyo). 1999 Dec;1(4):257-61
references.pmid: 12935478
references.citation: J Laryngol Otol. 1975 Sep;89(9):915-24
references.pmid: 1176826
references.citation: Arch Intern Med. 2002 Sep 23;162(17):2007-9
references.pmid: 12230425
references.citation: J Laryngol Otol. 1999 Jul;113(7):675-7
references.pmid: 10605570
references.citation: Laryngoscope. 2002 Aug;112(8 Pt 1):1426-30
references.pmid: 12172256
references.citation: B-ENT. 2007;3(4):209-11
references.pmid: 18265728
references.citation: Ear Nose Throat J. 2007 Feb;86(2):104-6
references.pmid: 17385620
references.citation: AJNR Am J Neuroradiol. 1996 Jun-Jul;17(6):1112-4
references.pmid: 8791924
references.citation: J Craniofac Surg. 2010 Nov;21(6):2022-4
references.pmid: 21119492
references.citation: B-ENT. 2010;6(3):215-7
references.pmid: 21090166
references.citation: Eur Arch Otorhinolaryngol. 2006 Mar;263(3):237-40
references.pmid: 16362263
references.citation: Indian J Otolaryngol Head Neck Surg. 2008 Sep;60(3):281-3
references.pmid: 23120564
references.citation: Clin Otolaryngol Allied Sci. 1988 Aug;13(4):267-72
references.pmid: 3180497
references.citation: Ann Otol Rhinol Laryngol. 2003 Apr;112(4):361-4
references.pmid: 12731632
references.citation: Acta Otorhinolaryngol Ital. 2012 Feb;32(1):58-62
references.pmid: 22500070
references.citation: Ann Otol Rhinol Laryngol. 1978 Sep-Oct;87(5 Pt 1):675-85
references.pmid: 718065