title: Decoding grasp force profile from electrocorticography signals in non-human primate sensorimotor cortex.
abstract: The relatively low invasiveness of electrocorticography (ECoG) has made it a promising candidate for the development of practical, high-performance neural prosthetics. Recent ECoG-based studies have shown success in decoding hand and finger movements and muscle activity in reaching and grasping tasks. However, decoding of force profiles is still lacking. Here, we demonstrate that lateral grasp force profile can be decoded using a sparse linear regression from 15 and 16 channel ECoG signals recorded from sensorimotor cortex in two non-human primates. The best average correlation coefficients of prediction after 10-fold cross validation were 0.82±0.09 and 0.79±0.15 for our monkeys A and B, respectively. These results show that grasp force profile was successfully decoded from ECoG signals in reaching and grasping tasks and may potentially contribute to the development of more natural control methods for grasping in neural prosthetics.
authors.affiliation: Department of Information Processing, Tokyo Institute of Technology, Yokohama, Japan.
authors.forename: Chao
authors.initials: C
authors.lastname: Chen
authors.affiliation: Precision and Intelligence Laboratory, Tokyo Institute of Technology, Yokohama, Japan. Electronic address: shinduk@cns.pi.titech.ac.jp.
authors.forename: Duk
authors.initials: D
authors.lastname: Shin
authors.affiliation: Department of Developmental Physiology, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki, Japan.
authors.forename: Hidenori
authors.initials: H
authors.lastname: Watanabe
authors.affiliation: Precision and Intelligence Laboratory, Tokyo Institute of Technology, Yokohama, Japan.
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Nakanishi
authors.affiliation: Precision and Intelligence Laboratory, Tokyo Institute of Technology, Yokohama, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kambara
authors.affiliation: Precision and Intelligence Laboratory, Tokyo Institute of Technology, Yokohama, Japan.
authors.forename: Natsue
authors.initials: N
authors.lastname: Yoshimura
authors.affiliation: Department of Integrative Physiology, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki, Japan; Graduate University for Advanced Studies (SOKENDAI), Hayama, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nambu
authors.affiliation: Department of Developmental Physiology, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki, Japan; Graduate University for Advanced Studies (SOKENDAI), Hayama, Japan.
authors.forename: Tadashi
authors.initials: T
authors.lastname: Isa
authors.affiliation: Department of Developmental Physiology, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki, Japan; Graduate University for Advanced Studies (SOKENDAI), Hayama, Japan; Precursory Research for Embryonic Science and Technology, Japan Science and Technology Agency, Tokyo, Japan.
authors.forename: Yukio
authors.initials: Y
authors.lastname: Nishimura
authors.affiliation: Department of Information Processing, Tokyo Institute of Technology, Yokohama, Japan; Precision and Intelligence Laboratory, Tokyo Institute of Technology, Yokohama, Japan.
authors.forename: Yasuharu
authors.initials: Y
authors.lastname: Koike
mesh_terms: D000465:Algorithms; D000818:Animals; D062207:Brain-Computer Interfaces; D004569:Electroencephalography / Q000379:methods; D005260:Female; D018737:Hand Strength / Q000502:physiology*; D000882:Haplorhini; D016014:Linear Models; D008297:Male; D066191:Sensorimotor Cortex / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted
keywords: Brain machine interfaces; Decoding force; Electrocorticography