title: [Results of non-rigid prosthetic reconstruction with expanded polytetrafluoro-ethylene( ePTFE) soft tissue patch following chest wall resection for malignant tumors].
abstract: Twenty patients underwent chest wall reconstruction using expanded polytetrafluoroethylene(ePTFE) soft tissue patch following resection between June 1996 and December 2012. The patients included 15 men and 5 women, aged 18 to 80 years. The indications for resection included 4 primary tumors, 8 metastatic tumors, and 8 infiltrating tumors. The lesions were located anteriorly in 10 patients, laterally in 5 patients and posteriorly in 5 patients. Skeletal resection involved an average of 2 ribs in 19 patients, and a partial sternectomy in 1 patient. The size of chest wall defects ranged from 20 to 210 cm2( mean, 69.8 cm2). Lung resection was performed in 7 patients included a wedge resection, 5 lobectomy, and a bilobectomy. Chest wall defects were closed primarily with ePTFE soft tissue patch. There were no critical complications or postoperative mortalities. The mean follow-up in all patients is 72.7 months. Recurrence of malignancy occurred in 10 patients included a local recurrence in 1 patient, and metastases in 9 patients. The overall postoperative 5-year survival rate is 61.0%. Non-rigid prosthetic reconstruction with ePTFE soft tissue patch provides satisfactory outcome. New prosthetic materials have to be examined whether they are superior to ePTFE soft tissue patch.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Hirosaki University School of Medicine, Hirosaki, Japan.
authors.forename: Takao
authors.initials: T
authors.lastname: Tsushima
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Kowatari
authors.forename: Daisuke
authors.initials: D
authors.lastname: Kimura
authors.forename: Takehiro
authors.initials: T
authors.lastname: Sakai
authors.forename: Ryo
authors.initials: R
authors.lastname: Hatanaka
authors.forename: Yoshitsugu
authors.initials: Y
authors.lastname: Yamada
authors.forename: Masahito
authors.initials: M
authors.lastname: Minakawa
authors.forename: Ikuo
authors.initials: I
authors.lastname: Fukuda
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011138:Polytetrafluoroethylene / Q000627:therapeutic use*; D019651:Plastic Surgery Procedures / Q000295:instrumentation*; D013899:Thoracic Neoplasms / Q000601:surgery*; D035441:Thoracic Wall / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D011138:Polytetrafluoroethylene