title: [Influencing factors of anxiety and depression in asthmatics].
abstract: OBJECTIVE
  To explore the major influencing factors for asthmatics with anxiety and depression.
  
  
  METHODS
  A total of 176 physician-diagnosed asthmatics were confirmed from March 2011 to March 2012 at First Affiliated Hospital of Zhengzhou University. And 144 were finally screened to examine their demographic characteristics and clinical features. Their status of anxiety and depression and the levels of control were evaluated with the scores of self-rating anxiety scale (SAS), self-rating depressive scale (SDS) and asthma control test (ACT). Firstly, asthma with anxiety and asthma with depression as a dependent variable, general demographics and clinical characteristics as independent variables, single-factor analysis revealed the relevant factors of asthma with anxiety and depression; secondly, multi-variable Logistic regression analysis was performed to examine the major influencing factors of anxiety and depression in asthmatics based on the relevant factors as independent variables.
  
  
  RESULTS
  Multiple variables Logistic regression showed that residing place (rural vs city/town, OR = 0.28); control levels (partly controlled vs uncontrolled, OR = 0.22; control vs non-control, OR = 0.10); severity (secondary vs first level, OR = 1.42; third vs first level, OR = 2.32; forth vs first level, OR = 3.12) were the major influencing factors of anxiety (all P < 0.05). Meanwhile, age (31-45 vs ≤ 30 years, OR = 11.35; >45 vs ≤ 30 years, OR = 18.73); level of education (junior high vs primary school and below, OR = 3.30; high/secondary vs primary school and below, OR = 3.52; college and above vs primary school and below, OR = 3.60), medical history (1-3 years vs <1 year, OR = 2.68; >3 years vs <1 year, OR = 3.01); control levels (partial control vs uncontrolled, OR = 0.25; controlled vs uncontrol, OR = 0.18) were the major influencing factors of depression (all P < 0.05).
  
  
  CONCLUSIONS
  Rural dwelling, poorly controlled and severe asthmatics are more likely to associate with anxiety. And depression moods are more common in those with an elder age, a long course of disease, higher education and poor control.
authors.affiliation: Department of Respiratory Medicine, Institute of Clinical Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China. Email: chengzhehi@126.com.
authors.forename: Zhe
authors.initials: Z
authors.lastname: Cheng
authors.affiliation: Department of Respiratory Medicine, Institute of Clinical Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
authors.forename: Ruiyun
authors.initials: R
authors.lastname: Li
authors.affiliation: Department of Respiratory Medicine, Institute of Clinical Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
authors.forename: Lingling
authors.initials: L
authors.lastname: Dai
authors.affiliation: Department of Respiratory Medicine, Institute of Clinical Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Respiratory Medicine, Institute of Clinical Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
authors.forename: Xi
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Respiratory Medicine, Institute of Clinical Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
authors.forename: Tianci
authors.initials: T
authors.lastname: Jiang
authors.affiliation: Department of Respiratory Medicine, Institute of Clinical Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Liu
authors.affiliation: Department of Respiratory Medicine, Institute of Clinical Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
authors.forename: Huan
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Respiratory Medicine, Institute of Clinical Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
authors.forename: Pengfei
authors.initials: P
authors.lastname: Li
authors.affiliation: Department of Respiratory Medicine, Institute of Clinical Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
authors.forename: Lin
authors.initials: L
authors.lastname: An
mesh_terms: D000328:Adult; D001007:Anxiety / Q000453:epidemiology*; D001249:Asthma / Q000453:epidemiology* / Q000523:psychology*; D003863:Depression / Q000453:epidemiology*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011795:Surveys and Questionnaires