title: Possible leap ahead in filovirus therapeutics.
abstract: In a recent study published in Nature, Warren et al. describe the generation of a novel synthetic adenosine analogue, BCX4430, a synthetic drug-like small molecule that provides protection from Ebola and Marburg virus infection in animal models.
authors.affiliation: Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA.
authors.forename: Darryl
authors.initials: D
authors.lastname: Falzarano
authors.affiliation: Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA.
authors.forename: Heinz
authors.initials: H
authors.lastname: Feldmann
mesh_terms: D000241:Adenosine / Q000031:analogs & derivatives*; D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D016563:Filoviridae / Q000187:drug effects*; D018702:Filoviridae Infections / Q000517:prevention & control* / Q000821:virology*; D006801:Humans; D011684:Purine Nucleosides / Q000494:pharmacology*
chemical_list: D000998:Antiviral Agents; D011684:Purine Nucleosides; D000241:Adenosine
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