title: Introduction to tobacco control supplement.
abstract: Electronic cigarettes (e-cigarettes) have recently gained significant attention in the marketplace and in the media. However, limited information is available about the worldwide impact of e-cigarettes; most public health officials are calling for more data so they can more fully understand the potential risks and benefits of e-cigarettes in order to inform regulatory action. In the USA, e-cigarettes that are marketed as tobacco products are not currently regulated by the Food and Drug Administration (FDA). However, having a continuum of nicotine-containing products that cross jurisdictional lines within the FDA in the future would create the potential (and the need) for a comprehensive nicotine strategy at the FDA. As part of developing the most appropriate approach to e-cigarette regulation, FDA Center for Tobacco Products scientists have been reviewing the available literature to determine the state of e-cigarette knowledge and have identified research areas that could be addressed. This supplement provides a summary of the current knowledge and research gaps pertaining to e-cigarettes with regards to product design, chemistry and toxicology of e-liquid and aerosol constituents, human factor-based risk factors, abuse liability, clinical pharmacology and human health effects, paediatric issues, and environmental issues.
authors.affiliation: Center for Tobacco Products, Food and Drug Administration, , Rockville, Maryland, USA.
authors.forename: Ii-Lun
authors.initials: IL
authors.lastname: Chen
authors.forename: Corinne G
authors.initials: CG
authors.lastname: Husten
mesh_terms: D066300:Electronic Nicotine Delivery Systems; D006801:Humans; D016540:Smoking Cessation / Q000331:legislation & jurisprudence / Q000379:methods; D014481:United States; D014486:United States Food and Drug Administration
keywords: Electronic nicotine delivery devices; Harm Reduction; Non-cigarette tobacco products
references.citation: Lancet Oncol. 2013 Oct;14(11):1027
references.pmid: 24079859
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references.pmid: 24259045