title: Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) in Strongyloides stercoralis Hyperinfection.
abstract: Strongyloides stercoralis (S. stercoralis) is a soil transmitted intestinal roundworm that has a unique ability to multiply within the human host and reinfect the human carrier by a process of autoinfection. By this property, S. stercoralis can persist as an occult infection for many decades. In situations of immunosuppression or other permissive gastrointestinal conditions, there occurs a massive increase in parasite multiplication. The parasites penetrate through the intestinal mucosa and are carried in circulation and can cause multisystem involvement. We report a case of a 76-year-old Columbian male who presented with intractable vomiting and hyponatremia who was then diagnosed to have syndrome of inappropriate antidiuretic hormone (SIADH). The patient's symptoms improved after treatment with two doses of ivermectin and his serum sodium levels returned to normal. S. stercoralis infection should be suspected in patients from endemic regions who present with gastrointestinal symptoms and unexplained hyponatremia.
authors.affiliation: Department of Internal Medicine, St. Joseph's Regional Medical Center, Paterson, New Jersey, USA.
authors.forename: Deepshikha Nag
authors.initials: DN
authors.lastname: Chowdhury
authors.affiliation: Division of Gastroenterology, Seton Hall University School of Health and Medical Sciences, South Orange, New Jersey, USA.
authors.forename: Gautamy Chitiki
authors.initials: GC
authors.lastname: Dhadham
authors.affiliation: Division of Gastroenterology, Seton Hall University School of Health and Medical Sciences, South Orange, New Jersey, USA.
authors.forename: Anish
authors.initials: A
authors.lastname: Shah
authors.affiliation: Division of Gastroenterology, Seton Hall University School of Health and Medical Sciences, South Orange, New Jersey, USA.
authors.forename: Walid
authors.initials: W
authors.lastname: Baddoura
keywords: Disseminated strongyloidiasis; Hyponatremia; Parasite; Strongyloides hyperinfection; Strongyloides stercoralis; Syndrome of inappropriate antidiuretic hormone secretion
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