title: Fostering hydroxyapatite bioactivity and mechanical strength by Si-doping and reinforcing with multiwall carbon nanotubes.
abstract: The aim of the present study was to prepare resorbable hydroxyapatite (HA) based bone graft materials reinforced with carbon nanotubes as a way to cope with the inability of pure HA to resorb and its intrinsic brittleness and poor strength that restrict its clinical applications under load-bearing conditions. With this purpose, a Si-doped HA nanopowder (n-Si0.8HA) was prepared by chemical synthesis and used as composite matrix reinforced with different amounts of functionalized multiwall carbon nanotubes (MWCNTs). The effect of the added amounts of MWCNTs on the mechanical properties of nanocomposites and their in vitro biomineralization was assessed by bending strength measurements, immersing tests in simulated body fluid solution (SBF), scanning electron microscopy (SEM), and inductively coupled plasma atomic emission spectroscopy analysis (ICP-AES). The bioactivity and bending strength were enhanced, reaching maximum balanced values for an optimum addition of 3 wt.% f-MWCNTs. These results might contribute to broaden the potential applications of HA-based bone grafts.
authors.forename: Younes
authors.initials: Y
authors.lastname: Belmamouni
authors.forename: Meriame
authors.initials: M
authors.lastname: Bricha
authors.forename: El Mokhtar
authors.initials: el M
authors.lastname: Essassi
authors.forename: José M F
authors.initials: JM
authors.lastname: Ferreira
authors.forename: Khalil
authors.initials: K
authors.lastname: El Mabrouk
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis; D001826:Body Fluids / Q000737:chemistry*; D019245:Compressive Strength; D003460:Crystallization / Q000379:methods; D017886:Durapatite / Q000737:chemistry*; D055119:Elastic Modulus; D008422:Materials Testing; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure*; D010316:Particle Size; D012825:Silicon / Q000737:chemistry*; D013314:Stress, Mechanical; D013499:Surface Properties; D013718:Tensile Strength
chemical_list: D001672:Biocompatible Materials; D037742:Nanotubes, Carbon; D017886:Durapatite; D012825:Silicon