title: Fe-catalyzed novel domino isomerization/cyclodehydration of substituted 2-[(indoline-3-ylidene)(methyl)]benzaldehyde derivatives: an efficient approach toward benzo[b]carbazole derivatives.
abstract: A new and efficient protocol to synthesize substituted benzo[b]carbazole derivatives has been demonstrated involving iron-catalyzed domino isomerization/cyclodehydration sequences from substituted 2-[(indoline-3-ylidene)(methyl)]benzaldehyde derivatives. The substrates could be easily made via Pd-catalyzed domino Heck-Suzuki coupling from 2-bromo-N-propargylanilide derivatives in high yields. Notably, the generality and efficiency of this two-stage domino strategy was further exemplified by the synthesis of a polycyclic benzofuran derivative.
authors.affiliation: Department of Chemistry, Jadavpur University , Kolkata 700 032, West Bengal, India.
authors.forename: Kartick
authors.initials: K
authors.lastname: Paul
authors.forename: Krishnendu
authors.initials: K
authors.lastname: Bera
authors.forename: Swapnadeep
authors.initials: S
authors.lastname: Jalal
authors.forename: Soumen
authors.initials: S
authors.lastname: Sarkar
authors.forename: Umasish
authors.initials: U
authors.lastname: Jana
mesh_terms: D001547:Benzaldehydes / Q000737:chemistry*; D001555:Benzene Derivatives / Q000138:chemical synthesis* / Q000737:chemistry; D002227:Carbazoles / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D002712:Chlorides / Q000737:chemistry*; D005025:Ethylene Dichlorides / Q000737:chemistry; D005290:Ferric Compounds / Q000737:chemistry*; D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis* / Q000737:chemistry; D007211:Indoles / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D001547:Benzaldehydes; D001555:Benzene Derivatives; D002227:Carbazoles; D002712:Chlorides; D005025:Ethylene Dichlorides; D005290:Ferric Compounds; D006576:Heterocyclic Compounds, 4 or More Rings; D007211:Indoles; C024565:ethylene dichloride; C057812:indoline; C024555:ferric chloride