title: Neuroendocrine cancer. An activating hotspot mutation in PRKACA provides clues for adrenal Cushing syndrome therapeutics.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Sargent
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000235:genetics* / Q000378:metabolism*; D018246:Adrenocortical Adenoma / Q000235:genetics* / Q000378:metabolism*; D003480:Cushing Syndrome / Q000235:genetics*; D054751:Cyclic AMP-Dependent Protein Kinase Catalytic Subunits / Q000235:genetics*; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism*
chemical_list: D054751:Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; D006854:Hydrocortisone
references.citation: Science. 2014 May 23;344(6186):913-7
references.pmid: 24700472