title: Emergence of Zaire Ebola virus disease in Guinea.
abstract: In March 2014, the World Health Organization was notified of an outbreak of a communicable disease characterized by fever, severe diarrhea, vomiting, and a high fatality rate in Guinea. Virologic investigation identified Zaire ebolavirus (EBOV) as the causative agent. Full-length genome sequencing and phylogenetic analysis showed that EBOV from Guinea forms a separate clade in relationship to the known EBOV strains from the Democratic Republic of Congo and Gabon. Epidemiologic investigation linked the laboratory-confirmed cases with the presumed first fatality of the outbreak in December 2013. This study demonstrates the emergence of a new EBOV strain in Guinea.
authors.affiliation: The authors' affiliations are listed in the Appendix.
authors.forename: Sylvain
authors.initials: S
authors.lastname: Baize
authors.forename: Delphine
authors.initials: D
authors.lastname: Pannetier
authors.forename: Lisa
authors.initials: L
authors.lastname: Oestereich
authors.forename: Toni
authors.initials: T
authors.lastname: Rieger
authors.forename: Lamine
authors.initials: L
authors.lastname: Koivogui
authors.forename: N'Faly
authors.initials: N
authors.lastname: Magassouba
authors.forename: Barrè
authors.initials: B
authors.lastname: Soropogui
authors.forename: Mamadou Saliou
authors.initials: MS
authors.lastname: Sow
authors.forename: Sakoba
authors.initials: S
authors.lastname: Keïta
authors.forename: Hilde
authors.initials: H
authors.lastname: De Clerck
authors.forename: Amanda
authors.initials: A
authors.lastname: Tiffany
authors.forename: Gemma
authors.initials: G
authors.lastname: Dominguez
authors.forename: Mathieu
authors.initials: M
authors.lastname: Loua
authors.forename: Alexis
authors.initials: A
authors.lastname: Traoré
authors.forename: Moussa
authors.initials: M
authors.lastname: Kolié
authors.forename: Emmanuel Roland
authors.initials: ER
authors.lastname: Malano
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Heleze
authors.forename: Anne
authors.initials: A
authors.lastname: Bocquin
authors.forename: Stephane
authors.initials: S
authors.lastname: Mély
authors.forename: Hervé
authors.initials: H
authors.lastname: Raoul
authors.forename: Valérie
authors.initials: V
authors.lastname: Caro
authors.forename: Dániel
authors.initials: D
authors.lastname: Cadar
authors.forename: Martin
authors.initials: M
authors.lastname: Gabriel
authors.forename: Meike
authors.initials: M
authors.lastname: Pahlmann
authors.forename: Dennis
authors.initials: D
authors.lastname: Tappe
authors.forename: Jonas
authors.initials: J
authors.lastname: Schmidt-Chanasit
authors.forename: Benido
authors.initials: B
authors.lastname: Impouma
authors.forename: Abdoul Karim
authors.initials: AK
authors.lastname: Diallo
authors.forename: Pierre
authors.initials: P
authors.lastname: Formenty
authors.forename: Michel
authors.initials: M
authors.lastname: Van Herp
authors.forename: Stephan
authors.initials: S
authors.lastname: Günther
mesh_terms: D000293:Adolescent; D000328:Adult; D001483:Base Sequence; D002648:Child; D004196:Disease Outbreaks; D029043:Ebolavirus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D005260:Female; D016701:Guinea / Q000453:epidemiology; D019142:Hemorrhagic Fever, Ebola / Q000453:epidemiology* / Q000821:virology; D006801:Humans; D008297:Male; D010802:Phylogeny; D012367:RNA, Viral / Q000032:analysis; D055815:Young Adult
chemical_list: D012367:RNA, Viral