title: Location of nonmelanoma skin cancers in patients after kidney transplantation.
abstract: BACKGROUND
  Long -term use of immunosuppressant therapy makes kidney transplant recipients particularly susceptible to infections and skin cancers.
  
  
  OBJECTIVE
  The aim of the study was to evaluate the type and location of nonmelanoma skin cancers (NMSCs) in patients after kidney transplantation.
  
  
  METHODS
  The study included 486 patients (296 men and 190 women; mean age, 46.1 ±13.1 years) after deceased -donor kidney transplantation, most of whom received triple immunosuppressive therapy. Patients underwent skin examination. All suspicious lesions were thoroughly described in terms of their type, size, and location. Only patients with histologically confirmed malignancy were included in the study.
  
  
  RESULTS
  Of all 486 patients, 25 were diagnosed with 53 NMSCs, including 39 basal cell carcinomas, 13 squamous cell carcinomas, and 1 case of Bowen's disease. The lesions were observed on the face (n = 34), upper limb (n = 8), neck (n = 6), and trunk (n = 5).
  
  
  CONCLUSIONS
  Most NMSCs were located on the sun -exposed areas, emphasizing the effect of ultraviolet radiation on the pathogenesis of skin cancers. The presence of lesions on the skin that had not been exposed to the sun indicates that a physical examination of the entire skin is necessary.
authors.forename: Joanna
authors.initials: J
authors.lastname: Sułowicz
authors.forename: Anna
authors.initials: A
authors.lastname: Wojas-Pelc
authors.forename: Ewa
authors.initials: E
authors.lastname: Ignacak
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Janda
authors.forename: Alina
authors.initials: A
authors.lastname: Bętkowska-Prokop
authors.forename: Marek
authors.initials: M
authors.lastname: Kuźniewski
authors.forename: Władysław
authors.initials: W
authors.lastname: Sułowicz
mesh_terms: D001913:Bowen's Disease / Q000453:epidemiology / Q000473:pathology; D002280:Basal Cell Carcinoma / Q000453:epidemiology / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000473:pathology; D015984:Causality; D015897:Comorbidity; D005260:Female; D006258:Head and Neck Neoplasms / Q000145:classification / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects / Q000706:statistics & numerical data*; D016030:Kidney Transplantation / Q000009:adverse effects / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000145:classification / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology*; D014466:Ultraviolet Rays / Q000009:adverse effects