title: Evaluating different aspects of prospective memory in amnestic and nonamnestic mild cognitive impairment.
abstract: Prospective memory, the inability to remember an intended action, is a common complaint, but not formally assessed in most clinical and research studies of mild cognitive impairment (MCI). In this study, patients with amnestic mild cognitive impairment (aMCI), non-amnestic cognitive impairment (naMCI), and cognitively normal (CN) elders were assessed using the Miami Prospective Memory Test (MPMT). A unique aspect of the paradigm was that participants were scored for intention to perform, accuracy in recollection for specific elements of the task, and the need for reminder cues. Excellent test-retest stability was obtained for MPMT Event-Related (ER), combined Time-Related (TR) subscales, and total MPMT score for aMCI subjects. MPMT impairments were observed in 48.6% of aMCI, 29.4% of naMCI, and 10.0% of normal elderly participants. Prospective memory deficits were common in participants with aMCI, and occurred in almost a third of naMCI participants. Intention to perform and need for reminder cues were significantly more impaired than retrospective memory for specific details of the task. It is concluded that assessment of different elements of prospective memory is important in MCI research and that inability to remember intended actions is a significant feature in those as risk for Alzheimer's disease.
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, FL 33134, USA.
authors.forename: Rene
authors.initials: R
authors.lastname: Hernandez Cardenache
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, FL 33134, USA.
authors.forename: Lizmar
authors.initials: L
authors.lastname: Burguera
authors.affiliation: Department of Psychology, Nova Southeastern University, Davie, FL 33314, USA.
authors.forename: Amarilis
authors.initials: A
authors.lastname: Acevedo
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, FL 33134, USA ; Center on Aging, Miller School of Medicine, University of Miami, FL 33134, USA.
authors.forename: Rosie
authors.initials: R
authors.lastname: Curiel
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, FL 33134, USA ; Center on Aging, Miller School of Medicine, University of Miami, FL 33134, USA.
authors.forename: David A
authors.initials: DA
authors.lastname: Loewenstein
references.citation: Arch Neurol. 2000 May;57(5):643-4
references.pmid: 10815128
references.citation: J Intern Med. 2004 Sep;256(3):183-94
references.pmid: 15324362
references.citation: Alzheimers Dement. 2011 May;7(3):270-9
references.pmid: 21514249
references.citation: J Int Neuropsychol Soc. 2010 Mar;16(2):318-25
references.pmid: 20128933
references.citation: Neuropsychology. 2006 Mar;20(2):144-52
references.pmid: 16594775
references.citation: J Int Neuropsychol Soc. 2009 May;15(3):407-15
references.pmid: 19402927
references.citation: J Consult Psychol. 1955 Oct;19(5):393-4
references.pmid: 13263471
references.citation: Neuropsychologia. 2006;44(8):1388-97
references.pmid: 16513147
references.citation: Dement Neuropsychol. 2011 Apr-Jun;5(2):64-68
references.pmid: 29213725
references.citation: Neuropsychologia. 2011 Jul;49(8):2147-55
references.pmid: 21192957
references.citation: Neurology. 1993 Nov;43(11):2412-4
references.pmid: 8232972
references.citation: Am J Geriatr Psychiatry. 1995 Autumn;3(4):300-307
references.pmid: 28531063
references.citation: J Int Neuropsychol Soc. 2012 Jul;18(4):706-16
references.pmid: 22595831
references.citation: Arch Gen Psychiatry. 1997 Mar;54(3):257-63
references.pmid: 9075466
references.citation: Dement Geriatr Cogn Disord. 2005;19(5-6):331-7
references.pmid: 15785034
references.citation: J Clin Exp Neuropsychol. 2006 May;28(4):536-48
references.pmid: 16676475
references.citation: J Am Geriatr Soc. 1997 Mar;45(3):321-8
references.pmid: 9063278
references.citation: Arch Neurol. 1995 May;52(5):485-90
references.pmid: 7733843
references.citation: J Clin Exp Neuropsychol. 1989 Dec;11(6):855-70
references.pmid: 2592527
references.citation: Acta Neurol Scand Suppl. 1996;165:63-71
references.pmid: 8740991