title: Correlation between post over preoperative surrogate insulin resistance indexes' ratios and reversal of metabolic syndrome after Roux-en-Y gastric bypass.
abstract: Metabolic syndrome (MetS) is strongly linked to insulin resistance and has a high resolution rate after bariatric surgery. This study aims to determine whether post over preoperative ratios of surrogate insulin resistance markers (HOMA, TyG, and TG/HDL-c) are associated to postsurgical MetS reversal. This is a retrospective cohort study which involved 96 subjects with MetS who underwent Roux-en-Y gastric bypass (RYGB). Post over preoperative ratios of TyG and TG/HDL-c indexes were statistically associated to MetS resolution. The use of these ratios as a way to assess postsurgical insulin sensitivity response appears to be a simple and useful tool in clinical practice.
authors.affiliation: Department of Surgery, Faculty of Medical Sciences, State University of Campinas (UNICAMP), R. Hermantino Coelho, 77/03-11, 13087-500, Campinas, Sao Paulo, Brazil, notrevezzo@yahoo.com.br.
authors.forename: Everton
authors.initials: E
authors.lastname: Cazzo
authors.forename: Francisco
authors.initials: F
authors.lastname: Callejas-Neto
authors.forename: José Carlos
authors.initials: JC
authors.lastname: Pareja
authors.forename: Elinton Adami
authors.initials: EA
authors.lastname: Chaim
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D008076:Cholesterol, HDL / Q000097:blood; D005260:Female; D015390:Gastric Bypass; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology*; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000150:complications / Q000517:prevention & control*; D008875:Middle Aged; D009767:Obesity, Morbid / Q000097:blood* / Q000150:complications / Q000601:surgery*; D012189:Retrospective Studies; D014280:Triglycerides / Q000097:blood; D055815:Young Adult
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D008076:Cholesterol, HDL; D014280:Triglycerides
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