title: Multiparametric magnetic resonance imaging of the prostate aids detect lesion progression.
abstract: Multiparametric magnetic resonance imaging (MRI) provides an accurate anatomical assessment of the tumor and its local staging. Herein, we report a case of intermediate-risk prostatic adenocarcinoma, initially followed on active surveillance, which upgraded from Gleason 7 (3 + 4) to Gleason 8 (4 + 4) on transrectal ultrasound/MRI fusion biopsy after progression of MR spectroscopic findings and review of the role of multiparametric MRI in the follow-up of patients with prostate cancer undergoing active surveillance.
authors.affiliation: *From the Molecular Pharmacology Section, Medical Oncology Branch, and †Molecular Imaging Program, National Cancer Institute, Bethesda, MD; ‡Urologic Oncology Branch, NCI, NIH, Bethesda, MD; §Center for Interventional Oncology, Radiology and Imaging Sciences CC, NIH, Bethesda, MD; ∥Clinical Pharmacology Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD; and ¶Laboratory of Pathology, NCI, NIH, Bethesda, MD.
authors.forename: Linda M
authors.initials: LM
authors.lastname: Johnson
authors.forename: Jason T
authors.initials: JT
authors.lastname: Rothwax
authors.forename: Baris
authors.initials: B
authors.lastname: Turkbey
authors.forename: Soroush
authors.initials: S
authors.lastname: Rais-Bahrami
authors.forename: Bradford J
authors.initials: BJ
authors.lastname: Wood
authors.forename: William D
authors.initials: WD
authors.lastname: Figg
authors.forename: Peter L
authors.initials: PL
authors.lastname: Choyke
authors.forename: Maria J
authors.initials: MJ
authors.lastname: Merino
authors.forename: Peter A
authors.initials: PA
authors.lastname: Pinto
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011467:Prostate / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014463:Ultrasonography; D036761:Ultrasound, High-Intensity Focused, Transrectal / Q000379:methods
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