title: Obsessions appear after the removal a brain tumor in the right frontal lobe.
abstract: A series of case reports and neuroimaging research points to the underlying neuropathological substrate for obsessive-compulsive disorder (OCD) and the underlying associations between OCD and areas of the frontal lobe. We report a patient wherein the onset of OCD occurred after resection of meningioma of the right frontal lobe and who was treated successfully with paroxetine hydrochloride. We suggest that the onset of secondary (organic) OCD is associated with the frontal lobe, and we propose that the origin of obsessions is located in the right frontal lobe.
authors.affiliation: Department of Psychology and Psychiatry, Medical College, Qingdao University, Qingdao, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Psychology and Psychiatry, Medical College, Qingdao University, Qingdao, China; Psychological Clinic, The Affiliated Hospital of Medical College, Qingdao University, Qingdao, China. Electronic address: xhzhang87@126.com.
authors.forename: Xinhua
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Radiology department, The Affiliated Hospital of Medical College, Qingdao University, Qingdao, China.
authors.forename: Jihua
authors.initials: J
authors.lastname: Liu
mesh_terms: D005260:Female; D005625:Frontal Lobe / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008577:Meningeal Neoplasms / Q000601:surgery*; D008579:Meningioma / Q000601:surgery*; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000009:adverse effects*; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy / Q000209:etiology*; D017374:Paroxetine / Q000008:administration & dosage / Q000494:pharmacology; D011183:Postoperative Complications / Q000503:physiopathology*; D017367:Selective Serotonin Reuptake Inhibitors / Q000008:administration & dosage / Q000494:pharmacology; D016896:Treatment Outcome
chemical_list: D017374:Paroxetine; D017367:Selective Serotonin Reuptake Inhibitors
keywords: Frontal lobe; Meningioma; Obsessive–Compulsive disorder