title: Clinical application of adipose stem cells in plastic surgery.
abstract: Adipose stem cells (ASCs) are a type of adult stem cells that share common characteristics with typical mesenchymal stem cells. In the last decade, ASCs have been shown to be a useful cell resource for tissue regeneration. The major role of regenerative medicine in this century is based on cell therapy in which ASCs hold a key position. Active research on this new type of adult stem cell has been ongoing and these cells now have several clinical applications, including fat grafting, overcoming wound healing difficulties, recovery from local tissue ischemia, and scar remodeling. The application of cultured cells will increase the efficiency of cell therapy. However, the use of cultured stem cells is strictly controlled by government regulation to ensure patient safety. Government regulation is a factor that can limit more versatile clinical application of ASCs. In this review, current clinical applications of ASCs in plastic surgery are introduced. Future stem cell applications in clinical field including culturing and banking of ASCs are also discussed in this review.
authors.affiliation: Department of Pathology, College of Medicine, Yeungnam University, Daegu, Korea.
authors.forename: Yong-Jin
authors.identifier: 0000-0002-9867-0752
authors.initials: YJ
authors.lastname: Kim
authors.affiliation: Oblige Plastic Surgery Clinic, Daegu, Korea.
authors.forename: Jae-Ho
authors.identifier: 0000-0002-9551-7154
authors.initials: JH
authors.lastname: Jeong
mesh_terms: D000273:Adipose Tissue / Q000166:cytology*; D002921:Cicatrix / Q000517:prevention & control; D006801:Humans; D007511:Ischemia / Q000628:therapy; D045164:Mesenchymal Stem Cell Transplantation; D059630:Mesenchymal Stem Cells / Q000166:cytology*; D013518:Surgery, Plastic; D023822:Tissue Engineering; D014945:Wound Healing
keywords: Adipose Stem Cells; Adipose Tissue; Adult Stem Cells; Cell Therapy; Ischemia; Mesenchymal Stem Cells; Regeneration; Stromal Cells; Tissue Engineering; Wound Healing
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