title: Comparative evaluation of sonographic ovarian morphology of Indian women with polycystic ovary syndrome versus those of normal women.
abstract: OBJECTIVE
  To study ovarian morphology by ultrasound in women with or without polycystic ovary syndrome (PCOS) and to establish cut-off values of these parameters in Indian women with PCOS.
  
  
  METHODS
  A total of 119 consecutive women diagnosed PCOS and 77 apparently healthy women were enrolled. Transabdominal ultrasound examination was carried out to assess ovarian volume, stromal echogenecity, follicle number and size. Cut-off values of the above ovarian parameters with sensitivity, specificity, positive predictive value (PPV) and negative predictive values (NPV) were calculated.
  
  
  RESULTS
  Sensitivity of 79.49% and specificity of 90.67% was achieved with a cut-off of 8 mL as ovarian volume. A cut-off value of 9 follicles to distinguish between PCOS and control women yielded a sensitivity of 82.35% and specificity of 92.0% while as a follicular size of 5 mm yielded sensitivity and specificity of 74.67% and 78.15% respectively. With all the three parameters sensitivity was 87.39% and specificity 87.84% with 92.04% PPV and 81.25% NPV.
  
  
  CONCLUSIONS
  Using two or three sonographic criteria in combination improves sensitivity and helps diagnose additional patients with PCOS. Our results are at variance with the established cut-off values highlighting the fact that American Society for Reproductive Medicine consensus cut-off values are not reproducible in Indian context.
authors.affiliation: Department of Radiodiagnosis, Sheri-Kashmir Institute of Medical Sciences, Srinagar, India.
authors.forename: Sanjeed
authors.initials: S
authors.lastname: Ahmed
authors.affiliation: Department of Radiodiagnosis, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
authors.forename: Shivani
authors.initials: S
authors.lastname: Pahwa
authors.affiliation: Department of Radiodiagnosis, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
authors.forename: Chandan Jyoti
authors.initials: CJ
authors.lastname: Das
authors.affiliation: Department of Radiodiagnosis, Sheri-Kashmir Institute of Medical Sciences, Srinagar, India.
authors.forename: Farooq A
authors.initials: FA
authors.lastname: Mir
authors.affiliation: Department of Geriatric Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
authors.forename: Sobia
authors.initials: S
authors.lastname: Nisar
authors.affiliation: Department of Radiodiagnosis, Government Medical College, Srinagar, Jammu and Kashmir, India.
authors.forename: Majid
authors.initials: M
authors.lastname: Jehangir
authors.affiliation: Department of Obstetrics and Gynecolgy, Sheri-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.
authors.forename: Shameem
authors.initials: S
authors.lastname: Parveen
authors.affiliation: Department of Endocrinology, Sheri-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.
authors.forename: Aafia
authors.initials: A
authors.lastname: Rashid
authors.affiliation: Department of Endocrinology, Metabolism and Diabetes, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
authors.forename: Mohd Ashraf
authors.initials: MA
authors.lastname: Ganie
keywords: Hyperandrogenism; ovarian volume; polycystic ovaries; thecal hyperechogenicity
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