title: Disseminated Fusarium oxysporum neurospinal infection.
abstract: We report a case of disseminated meningospondylodiscitis in an elderly diabetic patient caused by Fusarium oxysporum. As the clinical presentation was nonspecific, the diagnosis of the condition could only be arrived at after laboratory and imaging studies. The diagnosis of the condition requires a high index of suspicion. Patient underwent thorough surgical debridement along with a short course of variconazole and remained asymptomatic after 36 months of diagnosis. Fusarium is a large genus of filamentous fungi widely distributed in soil and in association with plants. It is known to cause local infections (nail, cornea) in healthy humans and disseminated infection only in the immunocompromised.
authors.affiliation: Department of Orthopedics, Kovai Medical Center and Hospital Ltd., Coimbatore, Tamil Nadu, India.
authors.forename: Pe
authors.initials: P
authors.lastname: Sreedharan Namboothiri
authors.affiliation: Department of Orthopedics, Kovai Medical Center and Hospital Ltd., Coimbatore, Tamil Nadu, India.
authors.forename: Sreehari Narayanan
authors.initials: SN
authors.lastname: Nair
authors.affiliation: Department of Neurology, Kovai Medical Center and Hospital Ltd., Coimbatore, Tamil Nadu, India.
authors.forename: Krishnan
authors.initials: K
authors.lastname: Vijayan
authors.affiliation: Department of Microbiology, Kovai Medical Center and Hospital Ltd., Coimbatore, Tamil Nadu, India.
authors.forename: Vk
authors.initials: V
authors.lastname: Visweswaran
keywords: Disseminated fungal meningospondylodiscitis; Fusarium oxysporum; voriconazole
references.citation: J Bone Joint Surg Am. 2001 Apr;83(4):560-5
references.pmid: 11315785
references.citation: Bratisl Lek Listy. 2008;109(8):345-7
references.pmid: 18837241
references.citation: Neurol India. 2007 Jul-Sep;55(3):241-50
references.pmid: 17921653
references.citation: AJR Am J Roentgenol. 1992 Jun;158(6):1333-45
references.pmid: 1590137
references.citation: NeuroRx. 2005 Apr;2(2):324-32
references.pmid: 15897953
references.citation: Radiology. 1985 Oct;157(1):157-66
references.pmid: 3875878
references.citation: J Infect. 2005 Jul;51(1):17-23
references.pmid: 15979485
references.citation: Case Rep Infect Dis. 2011;2011:460313
references.pmid: 22567471
references.citation: J Antimicrob Chemother. 2010 Nov;65 Suppl 3:iii11-24
references.pmid: 20876624