title: [Resected thymic hyperplasia with myasthenia gravis and Lambert-Eaton myasthenic syndrome].
abstract: A 61-year-old male who noticed muscular weakness of his extremities, diplopia and slur his words was found to have a thymic tumor on computed tomography. The immunological examination showed incremental of anti Acetylcholine receptor antibody titer and anti P/Q-type voltage-gated calcium channels antibody titer. Electromyography showed decremental response to low frequency stimulations, and incremental response to high frequency stimulations. So he was diagnosed with thymic tumor combined with myasthenia gravis and Lambert-Eaton myasthenic syndrome. He treated with extended thymomectomy resulting in the improvement of his neurological symptoms. Five years after operation, the patient is well without any malignant diseases.
authors.affiliation: Department of Thoracic Surgery, Tohoku Pharmaceutical University Hospital, Sendai, Japan.
authors.forename: Hideki
authors.initials: H
authors.lastname: Mitomo
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Tabata
authors.forename: Takafumi
authors.initials: T
authors.lastname: Sugawara
authors.forename: Akira
authors.initials: A
authors.lastname: Miyamoto
authors.forename: Shigefumi
authors.initials: S
authors.lastname: Fujimura
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Murakami
mesh_terms: D006801:Humans; D015624:Lambert-Eaton Myasthenic Syndrome / Q000150:complications* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications* / Q000601:surgery*; D013934:Thymectomy; D013950:Thymus Gland / Q000002:abnormalities* / Q000601:surgery