title: An aberrant microRNA signature in childhood T-cell lymphoblastic lymphoma affecting CDKN1B expression, NOTCH1 and growth factor signaling pathways.
authors.affiliation: 1] Istituto di Ricerca Pediatrico Fondazione Citta' della Speranza, Padova, Italy [2] Clinica di Oncoematologia Pediatrica, Azienda Ospedaliera-Universita' di Padova, Padova, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Mussolin
authors.affiliation: Institute for Cancer Genetics, Columbia University, New York, NY, USA.
authors.forename: A B
authors.initials: AB
authors.lastname: Holmes
authors.affiliation: Department of Biology, University of Padova, Padova, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Romualdi
authors.affiliation: Department of Biology, University of Padova, Padova, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Sales
authors.affiliation: Department of Pathology, San Bortolo Hospital, Vicenza, Italy.
authors.forename: E S G
authors.initials: ES
authors.lastname: D'Amore
authors.affiliation: Department of Oncology and Surgical Sciences, University of Padova, Padova, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Ghisi
authors.affiliation: Clinica di Oncoematologia Pediatrica, Azienda Ospedaliera-Universita' di Padova, Padova, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Pillon
authors.affiliation: 1] Istituto di Ricerca Pediatrico Fondazione Citta' della Speranza, Padova, Italy [2] Clinica di Oncoematologia Pediatrica, Azienda Ospedaliera-Universita' di Padova, Padova, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Rosolen
authors.affiliation: 1] Institute for Cancer Genetics, Columbia University, New York, NY, USA [2] Department of Pathology and Cell Biology, Columbia University, New York, NY, USA.
authors.forename: K
authors.initials: K
authors.lastname: Basso
mesh_terms: D050760:Cyclin-Dependent Kinase Inhibitor p27 / Q000235:genetics*; D006801:Humans; D035683:MicroRNAs / Q000502:physiology*; D010982:Platelet-Derived Growth Factor / Q000502:physiology; D054218:Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics* / Q000473:pathology; D012333:RNA, Messenger / Q000032:analysis; D051881:Receptor, Notch1 / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*
chemical_list: C436291:CDKN1B protein, human; D035683:MicroRNAs; D010982:Platelet-Derived Growth Factor; D012333:RNA, Messenger; D051881:Receptor, Notch1; D050760:Cyclin-Dependent Kinase Inhibitor p27
references.citation: Leukemia. 2012 Sep;26(9):2011-8
references.pmid: 22456625
references.citation: Proc Natl Acad Sci U S A. 2012 May 15;109(20):7865-70
references.pmid: 22550173
references.citation: Br J Haematol. 2010 Jun;149(5):653-68
references.pmid: 19961482
references.citation: Nat Protoc. 2009;4(1):44-57
references.pmid: 19131956
references.citation: Nat Genet. 2011 Jun 05;43(7):673-8
references.pmid: 21642990
references.citation: J Exp Med. 2013 Jul 29;210(8):1545-57
references.pmid: 23857984
references.citation: J Biol Chem. 2010 Nov 5;285(45):34439-46
references.pmid: 20826802
references.citation: Blood. 2011 Jun 30;117(26):7053-62
references.pmid: 21551231
references.citation: Cell Stem Cell. 2013 Jul 3;13(1):87-101
references.pmid: 23827711
references.citation: Genome Biol. 2010;11(8):R90
references.pmid: 20799968
references.citation: Expert Opin Investig Drugs. 2014 Feb;23(2):211-26
references.pmid: 24206431
references.citation: EMBO J. 2007 Aug 8;26(15):3699-708
references.pmid: 17627278
references.citation: Genes Chromosomes Cancer. 2011 Dec;50(12):1063-75
references.pmid: 21987448
references.citation: Blood. 2010 Jan 7;115(1):51-60
references.pmid: 19880494
references.citation: Exp Hematol Oncol. 2013 Apr 08;2(1):10
references.pmid: 23566596