title: Long-term mortality in a cohort of home-dwelling elderly with mild Alzheimer's disease and Lewy body dementia.
abstract: OBJECTIVE
  To study mortality in subjects with mild dementia in Norway with a special focus on patients with Lewy body dementia (LBD) compared to Alzheimer's disease (AD).
  
  
  METHODS
  All referrals of mild dementia patients to dementia clinics in western Norway from March 2005 to March 2007 were included and followed until December 2012. Diagnoses were based on a comprehensive standardized assessment program.
  
  
  RESULTS
  Of 209 patients, 137 (66%) had AD and 53 (25%) had LBD. Dementia was associated with increased mortality (standardized mortality ratio = 1.8, AD 1.5, LBD 2.6). The median survival time was 6.2 years (95% CI 5.4-6.9). Predictors of mortality were age at diagnosis (HR 1.1 per year) and LBD diagnosis (HR 2.4).
  
  
  CONCLUSIONS
  Dementia patients had an increased mortality, particularly those with LBD.
authors.affiliation: Centre for Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway.
authors.forename: Ragnhild
authors.initials: R
authors.lastname: Oesterhus
authors.forename: Hogne
authors.initials: H
authors.lastname: Soennesyn
authors.forename: Arvid
authors.initials: A
authors.lastname: Rongve
authors.forename: Clive
authors.initials: C
authors.lastname: Ballard
authors.forename: Dag
authors.initials: D
authors.lastname: Aarsland
authors.forename: Corinna
authors.initials: C
authors.lastname: Vossius
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000401:mortality*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D020961:Lewy Body Disease / Q000401:mortality*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009664:Norway; D012111:Residence Characteristics; D015996:Survival Rate