title: Streptococcus gallolyticus subsp. pasteurianus meningitis in an infant.
abstract: Streptococcus gallolyticus subsp. pasteurianus was formerly classified as S. bovis biotype II/2, which is recognized as a rare cause of neonatal sepsis and meningitis. Since the taxonomy classification change, there have not been many reports of meningitis due to S. gallolyticus subsp. pasteurianus. Moreover, the pathogenesis of late onset S. gallolyticus subsp. pasteurianus meningitis in infants is unclear. Here we report a case of meningitis in a 5-week-old infant with preceding diarrhea. S. bovis biotype II/2 was isolated from the blood, cerebrospinal fluid and stool, and then was identified as S. gallolyticus subsp. pasteurianus on 16S rRNA gene sequencing. Isolates from all three sample types had identical profiles on pulsed-field gel electrophoresis. The intestinal tract was thought to be the source of the infection.
authors.affiliation: Department of Pediatrics, Teikyo University Chiba Medical Center, Chiba, Japan; Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba, Japan.
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Takahashi
authors.forename: Naruhiko
authors.initials: N
authors.lastname: Ishiwada
authors.forename: Junko
authors.initials: J
authors.lastname: Tanaka
authors.forename: Kiyofumi
authors.initials: K
authors.lastname: Okusu
authors.forename: Sadahiro
authors.initials: S
authors.lastname: Ichimura
authors.forename: Haruka
authors.initials: H
authors.lastname: Hishiki
authors.forename: Setsuo
authors.initials: S
authors.lastname: Ota
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Kohno
mesh_terms: D001483:Base Sequence; D006801:Humans; D007223:Infant; D008297:Male; D016920:Meningitis, Bacterial; D008969:Molecular Sequence Data; D013290:Streptococcal Infections; D013291:Streptococcus / Q000145:classification / Q000235:genetics
keywords: Streptococcus bovis; Streptococcus gallolyticus subsp. pasteurianus; infant; meningitis; pulsed-field gel electrophoresis