title: [Nucleic acid aptamers in diagnosis of diseases].
abstract: Aptamers are single-stranded oligonucleotide ligands selected from a random pool of oligonucleotide sequences by systematic evolution of ligands by exponential enrichment. With the advantages of binding to targets with high specificity and affinity, aptamers have been used in the diagnosis widely, such as biochemistry detection, discovery of new tumor markers, molecular imaging, pathogenic and microorganism detection, showing a good application prospect.
authors.affiliation: Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
authors.forename: Pan
authors.initials: P
authors.lastname: Zhang
authors.forename: Kunhe
authors.initials: K
authors.lastname: Zhang
mesh_terms: D052157:Aptamers, Nucleotide; D003933:Diagnosis; D004194:Disease; D006801:Humans; D012680:Sensitivity and Specificity
chemical_list: D052157:Aptamers, Nucleotide