title: Genome-scale metabolic models of yeast, methods for their reconstruction, and other applications.
abstract: Here, we present the concept of genome-scale metabolic models and some of their applications in metabolic engineering of yeast and in the analysis of gene expression data. The yeast species for which there are available genome-scale metabolic models are reviewed, as well as the methods for the reconstruction of genome-scale metabolic models for new species. Some commonly used algorithms for metabolic engineering and data integration are described.
authors.affiliation: Department of Chemical and Biological Engineering, Chalmers University of Technology, Kemivägen 10, Gothenburg, 412 96, Sweden, velasco@chalmers.se.
authors.forename: Sergio
authors.initials: S
authors.lastname: Bordel
mesh_terms: D016681:Genome, Fungal / Q000235:genetics; D023281:Genomics / Q000379:methods*; D060847:Metabolic Engineering; D008954:Models, Biological; D049490:Systems Biology; D015003:Yeasts / Q000235:genetics*