title: Amino group binding peptide aptamers with double disulphide-bridged loops selected by in vitro selection using cDNA display.
abstract: Peptide aptamers that specifically bind to the amino group on a solid-phase were screened by in vitro selection using the cDNA display method. The identified peptides have a unique structure containing two cyclic loops with disulphide bonds and a linkage region, which were indispensable for molecular recognition.
authors.affiliation: Graduate School of Science and Engineering, Saitama University, 255 Shimo-Okubo, Sakura-ku, Saitama 338-8570, Japan. nemoto@fms.saitama-u.ac.jp.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Mochizuki
authors.forename: Koichi
authors.initials: K
authors.lastname: Nishigaki
authors.forename: Naoto
authors.initials: N
authors.lastname: Nemoto
mesh_terms: D000595:Amino Acid Sequence; D052158:Aptamers, Peptide / Q000737:chemistry* / Q000378:metabolism*; D018076:DNA, Complementary / Q000235:genetics; D004220:Disulfides / Q000737:chemistry*; D059346:Magnets / Q000737:chemistry; D008863:Microspheres; D008969:Molecular Sequence Data; D019151:Peptide Library; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D011137:Polystyrenes / Q000737:chemistry
chemical_list: D052158:Aptamers, Peptide; D018076:DNA, Complementary; D004220:Disulfides; D019151:Peptide Library; D010455:Peptides; D011137:Polystyrenes