title: Pyomyositis Causing Temporary Quadriparesis During Induction Therapy for Acute Lymphoblastic Leukemia: Case Report and Review of the Literature.
abstract: Pyomyositis (PM) is a purulent infection of skeletal muscle. It is often associated with immunosuppression in temperate climates. Herein, we report a case of PM causing temporary quadriparesis in a 14-year-old girl undergoing induction therapy for acute lymphoblastic leukemia and we review the reported pediatric cases associated with induction therapy for hematologic malignancies. Early symptoms of PM can be mistaken for the side effects of chemotherapeutic agents. Greater awareness of the clinical picture of PM will aid in early diagnosis and treatment. With appropriate medical therapy and timely abscess drainage, morbidity and mortality is greatly reduced.
authors.affiliation: Departments of *Medicine †Pediatrics, McMaster University, Hamilton, ON, Canada.
authors.forename: Nazanin
authors.initials: N
authors.lastname: Montazeri
authors.forename: Uma H
authors.initials: UH
authors.lastname: Athale
authors.forename: Martha
authors.initials: M
authors.lastname: Fulford
authors.forename: Mark A
authors.initials: MA
authors.lastname: Tarnopolsky
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D005260:Female; D006801:Humans; D060828:Induction Chemotherapy / Q000009:adverse effects*; D018482:Muscle, Skeletal / Q000473:pathology*; D009367:Neoplasm Staging; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D011379:Prognosis; D052880:Pyomyositis / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D011782:Quadriplegia / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents