title: [Comparative evaluation of 2 antiemesis tools for the prevention of chemotherapy-induced nausea and vomiting].
abstract: Although recent advances in chemotherapy have led to improved quality of life(QOL)and prolonged survival in patients with advanced cancer, treatment is often discontinued because of adverse events associated with chemotherapy, regardless of its efficacy.Nevertheless, chemotherapy has been validated in the United States and United Kingdom and is used worldwide. In Japan, few reports have been published regarding the use of assessment tools including the Multinational Association of Supportive Care in Cancer(MASCC)Antiemesis Tool(MAT)for the evaluation of chemotherapy-induced nausea and vomiting(CINV).We prospectively investigated the utility of the MAT and digestive symptom diary(DSD).In total, 68 patients who underwent highly and moderately emetogenic chemotherapy were included in the efficacy analyses.The improvement in the control of CINV during the delayed phase was significantly different between the DSD and MAT groups(p= 0.0148).The results obtained using the MAT warrant further validation.Meanwhile, the DSD may be used as an information tool by medical staff and patients.
authors.affiliation: Dept. of Hospital Pharmacy, Osaka Police Hospital.
authors.forename: Hisae
authors.initials: H
authors.lastname: Murata
authors.forename: Yuri
authors.initials: Y
authors.lastname: Teramoto
authors.forename: Makiko
authors.initials: M
authors.lastname: Kawashita
authors.forename: Miwa
authors.initials: M
authors.lastname: Oi
authors.forename: Takeyoshi
authors.initials: T
authors.lastname: Kitaguchi
authors.forename: Emi
authors.initials: E
authors.lastname: Sasahira
authors.forename: Atsumi
authors.initials: A
authors.lastname: Masuda
authors.forename: Yumi
authors.initials: Y
authors.lastname: Satake
authors.forename: Sachiko
authors.initials: S
authors.lastname: Enomoto
authors.forename: Chiho
authors.initials: C
authors.lastname: Komai
authors.forename: Midori
authors.initials: M
authors.lastname: Udo
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Komuta
authors.forename: Katsumi
authors.initials: K
authors.lastname: Yamamoto
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000932:Antiemetics / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009325:Nausea / Q000139:chemically induced / Q000517:prevention & control*; D009369:Neoplasms / Q000188:drug therapy*; D011795:Surveys and Questionnaires; D014839:Vomiting / Q000139:chemically induced / Q000517:prevention & control*
chemical_list: D000932:Antiemetics; D000970:Antineoplastic Agents