title: Impact of postoperative renal replacement therapy on long-term outcome after cardiac surgery increases with age.
abstract: OBJECTIVE
  In the present study, we investigated the survival of patients who received postoperative renal replacement therapy (RRT) after cardiac surgery. We specifically focused on factors predicting long-term outcome in elderly patients.
  
  
  METHODS
  Data of all patients that received unintentional renal replacement therapy following cardiac surgery between 2004 and 2010 were analyzed. Logistic- and Cox regression analyses were performed to detect the predictors of early and late mortality, respectively.
  
  
  RESULTS
  During the study period, 11,899 patients underwent cardiac surgery in our center. Post-operative RRT was performed in 138 patients (1.2%). In this group of patients, 30-day mortality included 72 patients (52%) and the total overall mortality included 107 patients (77.5%). Regression analyses revealed that age predicted 30-day mortality (odds ratio = 1.08 [1.03 to 1.12]) as well as late mortality (odds ratio = 1.05 [1.02 to 1.07].
  
  
  CONCLUSIONS
  Patients requiring RRT after cardiac surgery have a poor prognosis with a high mortality. Older age predicted both 30-day and late mortality in these patients.
authors.affiliation: Department of Anesthesiology, Intensive Care Unit, Catharina Hospital, Eindhoven, The Netherlands; Intensive Care Unit, Catharina Hospital, Eindhoven, The Netherlands.
authors.forename: Marco C
authors.initials: MC
authors.lastname: Haanschoten
authors.forename: Albert H M
authors.initials: AH
authors.lastname: van Straten
authors.forename: Arthur
authors.initials: A
authors.lastname: Bouwman
authors.forename: Alexander J G H
authors.initials: AJ
authors.lastname: Bindels
authors.forename: André A J
authors.initials: AA
authors.lastname: van Zundert
authors.forename: Mohamed A
authors.initials: MA
authors.lastname: Soliman Hamad
mesh_terms: D058186:Acute Kidney Injury / Q000628:therapy*; D000367:Age Factors; D000368:Aged; D006348:Cardiac Surgical Procedures; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D011182:Postoperative Care; D011183:Postoperative Complications / Q000628:therapy*; D016016:Proportional Hazards Models; D017582:Renal Replacement Therapy / Q000401:mortality / Q000706:statistics & numerical data; D012307:Risk Factors; D015996:Survival Rate; D013997:Time Factors; D016896:Treatment Outcome