title: The endocannabinoid system and the neuroendocrine control of hydromineral balance.
abstract: Endocannabinoids (ECBs) are ubiquitous lipophilic agents, and this characteristic is consistent with the wide range of homeostatic functions attributed to the ECB system. There is an increasing number of studies showing that the ECB system affects neurotransmission within the hypothalamic neurohypophyseal system. We provide an overview of the primary roles of ECBs in the modulation of neuroendocrine function and, specifically, in the control of hydromineral homeostasis. Accordingly, the general aspects of ECB-mediated signalling, as well as the specific contributions of the central component of the ECB system to the integration of behavioural and endocrine responses that control body fluid homeostasis, are discussed.
authors.affiliation: Departamento de Fisiologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
authors.forename: S G
authors.initials: SG
authors.lastname: Ruginsk
authors.forename: F M V
authors.initials: FM
authors.lastname: Vechiato
authors.forename: L L K
authors.initials: LL
authors.lastname: Elias
authors.forename: J
authors.initials: J
authors.lastname: Antunes-Rodrigues
mesh_terms: D000818:Animals; D063388:Endocannabinoids / Q000502:physiology*; D006801:Humans; D008903:Minerals / Q000378:metabolism*; D009490:Neurosecretory Systems / Q000502:physiology*; D043884:Receptor, Cannabinoid, CB1 / Q000187:drug effects; D043882:Receptors, Cannabinoid / Q000502:physiology; D014882:Water-Electrolyte Balance / Q000502:physiology*
chemical_list: D063388:Endocannabinoids; D008903:Minerals; D043884:Receptor, Cannabinoid, CB1; D043882:Receptors, Cannabinoid
keywords: endocannabinoids; hydromineral homeostasis; type 1 cannabinoid receptor