title: Delayed appearance of wing-beating tremor after liver transplantation in a patient with Wilson disease.
abstract: Orthotopic liver transplantation (OLT) is the sole etiological treatment for Wilson disease (WD), but several neurological complications after OLT have been reported. We report a WD patient who developed a unilateral wing-beating tremor 6years after OLT. New neurological symptoms develop immediately after OLT in most cases. In our patient, the onset of extrapyramidal symptoms was at a prolonged interval after OLT. To our knowledge this is the first patient with delayed extrapyramidal symptoms after OLT in WD where the pathophysiology of these late extrapyramidal symptoms is still unknown.
authors.affiliation: Department of Neurology, College of Medicine, The Catholic University of Korea, Seoul St. Mary's Hospital, 505, Banpo-dong, Seocho-gu, Seoul 137-701, Republic of Korea. Electronic address: neuronet@catholic.ac.kr.
authors.forename: Joong-Seok
authors.initials: JS
authors.lastname: Kim
authors.affiliation: Department of Pathology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
authors.forename: Su-Young
authors.initials: SY
authors.lastname: Kim
authors.affiliation: Division of Hepatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
authors.forename: Jong-Young
authors.initials: JY
authors.lastname: Choi
authors.affiliation: Department of Neurology, Hanyang University School of Medicine, Seoul, Republic of Korea.
authors.forename: Hee-Tae
authors.initials: HT
authors.lastname: Kim
authors.affiliation: Department of Neurology, College of Medicine, The Catholic University of Korea, Seoul St. Mary's Hospital, 505, Banpo-dong, Seocho-gu, Seoul 137-701, Republic of Korea.
authors.forename: Yoon-Sang
authors.initials: YS
authors.lastname: Oh
mesh_terms: D001706:Biopsy; D005260:Female; D006527:Hepatolenticular Degeneration / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008099:Liver / Q000473:pathology; D016031:Liver Transplantation / Q000009:adverse effects*; D008875:Middle Aged; D013997:Time Factors; D014202:Tremor / Q000209:etiology* / Q000503:physiopathology; D014741:Video Recording
keywords: Delayed; Orthotopic liver transplantation; Tremor; Wilson disease