title: Investigation of the role of major respiratory viruses in the aetiology of nasal polyps using polymerase chain reaction technique.
abstract: OBJECTIVE
  We aimed to identify the role of major respiratory viruses in the aetiology of human nasal polyps using polymerase chain reaction technique.
  
  
  METHODS
  Thirty patients with nasal polyps and a group of 20 healthy patients (control group) were included in this study. Mucosa was obtained from the polyps of patients with nasal polyposis and from the middle turbinate of the control group patients by means of biopsy. The samples were stored at -80 °C until molecular analysis by polymerase chain reaction was carried out.
  
  
  RESULTS
  In the control group, the human coronavirus and human rhinovirus were diagnosed in one of the patients and the human respiratory syncytial virus in another. In the group with nasal polyposis, the influenza B virus was identified in one of the patients and the human coronavirus in another.
  
  
  CONCLUSIONS
  The results did not demonstrate a statistically significant relationship between nasal polyposis and respiratory viruses.
authors.affiliation: Department of Otorhinolaryngology, Bezmiâlem Vakif University, Istanbul, Turkey.
authors.forename: F
authors.initials: F
authors.lastname: Aksoy
authors.affiliation: Otorhinolaryngology Clinic, Karaman State Hospital, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Yenigun
authors.affiliation: Department of Otorhinolaryngology, Bezmiâlem Vakif University, Istanbul, Turkey.
authors.forename: R
authors.initials: R
authors.lastname: Dogan
authors.affiliation: Department of Otorhinolaryngology, Medipol University, Istanbul, Turkey.
authors.forename: F
authors.initials: F
authors.lastname: Yilmaz
authors.affiliation: Department of Otorhinolaryngology, Bezmiâlem Vakif University, Istanbul, Turkey.
authors.forename: O
authors.initials: O
authors.lastname: Ozturan
authors.affiliation: Department of Medical Genetics, Konya Selcuk University, Turkey.
authors.forename: V B
authors.initials: VB
authors.lastname: Yenigun
mesh_terms: D009298:Nasal Polyps / Q000150:complications / Q000473:pathology / Q000821:virology; D014777:Virus Diseases / Q000150:complications / Q000821:virology; D006801:Humans; D016133:Polymerase Chain Reaction; D016022:Case-Control Studies; D005260:Female; D000328:Adult; D008875:Middle Aged; D000368:Aged; D009297:Nasal Mucosa / Q000473:pathology / Q000821:virology; D014780:Viruses / Q000235:genetics / Q000302:isolation & purification
keywords: Nasal Polyps; Polymerase Chain Reaction; Respiratory Syncytial Viruses