title: Successful platelet count recovery in lupus-associated thrombocytopenia with the thrombopoietin agonist eltrombopag.
abstract: Eltrombopag is a new thrombomimetic medication approved for the treatment of immune thrombocytopenia. There are very few reports on the use of eltrombopag in patients with thrombocytopenia associated with sytemic lupus.We present a recent case of a patient with lupus with severe thrombocytopenia refractory to conventional therapy and full recovery with the use of eltrombopag. The present status of the literature with the use of this medication in patients with lupus is reviewed and discussed.
authors.affiliation: Hematology Service, Oncology Center, Hospital São José, Beneficência Portuguesa, São Paulo, Brazil.
authors.forename: Phillip
authors.initials: P
authors.lastname: Scheinberg
authors.forename: Cristiane Carvalho
authors.initials: CC
authors.lastname: Singulane
authors.forename: Luis Sergio Guedes
authors.initials: LS
authors.lastname: Barbosa
authors.forename: Morton
authors.initials: M
authors.lastname: Scheinberg
mesh_terms: D000328:Adult; D001565:Benzoates / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006834:Hydrazines / Q000627:therapeutic use*; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D010976:Platelet Count; D011720:Pyrazoles / Q000627:therapeutic use*; D053628:Receptors, Thrombopoietin / Q000819:agonists*; D013921:Thrombocytopenia / Q000188:drug therapy* / Q000209:etiology; D016896:Treatment Outcome
chemical_list: D001565:Benzoates; D006834:Hydrazines; D011720:Pyrazoles; D053628:Receptors, Thrombopoietin; C520809:eltrombopag
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