title: Cross-talk between probiotic lactobacilli and host immune system.
abstract: The mechanism by which probiotic lactobacilli affect the immune system is strain specific. As the immune system is a multicompartmental system, each strain has its way to interact with it and induce a visible and quantifiable effect. This review summarizes the interplay existing between the host immune system and probiotic lactobacilli, that is, with emphasis on lactobacilli as a prototype probiotic genus. Several aspects including the bacterial-host cross-talk with the mucosal and systemic immune system are presented, as well as short sections on the competing effect towards pathogenic bacteria and their uses as delivery vehicle for antigens.
authors.affiliation: Department of Animal Biochemistry, National Dairy Research Institute, Karnal, Haryana, India; Department of Food Science/Nutrition, National School of AgroIndustrial Sciences, University of Ngaoundere, Ngaoundere, Adamaoua, Cameroon.
authors.forename: T S
authors.initials: TS
authors.lastname: Kemgang
authors.forename: S
authors.initials: S
authors.lastname: Kapila
authors.forename: V P
authors.initials: VP
authors.lastname: Shanmugam
authors.forename: R
authors.initials: R
authors.lastname: Kapila
mesh_terms: D001419:Bacteria / Q000276:immunology; D006801:Humans; D007107:Immune System / Q000276:immunology*; D018928:Immunity, Mucosal; D007422:Intestines / Q000382:microbiology; D007778:Lactobacillus / Q000235:genetics / Q000276:immunology*; D019936:Probiotics
keywords: lactobacilli; mechanism; mucosal immune system; probiotics; systemic immune system