title: Automatic 4D reconstruction of patient-specific cardiac mesh with 1-to-1 vertex correspondence from segmented contours lines.
abstract: We propose an automatic algorithm for the reconstruction of patient-specific cardiac mesh models with 1-to-1 vertex correspondence. In this framework, a series of 3D meshes depicting the endocardial surface of the heart at each time step is constructed, based on a set of border delineated magnetic resonance imaging (MRI) data of the whole cardiac cycle. The key contribution in this work involves a novel reconstruction technique to generate a 4D (i.e., spatial-temporal) model of the heart with 1-to-1 vertex mapping throughout the time frames. The reconstructed 3D model from the first time step is used as a base template model and then deformed to fit the segmented contours from the subsequent time steps. A method to determine a tree-based connectivity relationship is proposed to ensure robust mapping during mesh deformation. The novel feature is the ability to handle intra- and inter-frame 2D topology changes of the contours, which manifests as a series of merging and splitting of contours when the images are viewed either in a spatial or temporal sequence. Our algorithm has been tested on five acquisitions of cardiac MRI and can successfully reconstruct the full 4D heart model in around 30 minutes per subject. The generated 4D heart model conforms very well with the input segmented contours and the mesh element shape is of reasonably good quality. The work is important in the support of downstream computational simulation activities.
authors.affiliation: Institute of High Performance Computing, A*STAR, Singapore, Singapore.
authors.forename: Chi Wan
authors.initials: CW
authors.lastname: Lim
authors.affiliation: Institute of High Performance Computing, A*STAR, Singapore, Singapore.
authors.forename: Yi
authors.initials: Y
authors.lastname: Su
authors.affiliation: Institute of High Performance Computing, A*STAR, Singapore, Singapore.
authors.forename: Si Yong
authors.initials: SY
authors.lastname: Yeo
authors.affiliation: Institute of High Performance Computing, A*STAR, Singapore, Singapore.
authors.forename: Gillian Maria
authors.initials: GM
authors.lastname: Ng
authors.affiliation: Institute of High Performance Computing, A*STAR, Singapore, Singapore.
authors.forename: Vinh Tan
authors.initials: VT
authors.lastname: Nguyen
authors.affiliation: National Heart Centre Singapore, Singapore.
authors.forename: Liang
authors.initials: L
authors.lastname: Zhong
authors.affiliation: National Heart Centre Singapore, Singapore.
authors.forename: Ru San
authors.initials: RS
authors.lastname: Tan
authors.affiliation: Cardiac Department, National University Heart Center, National University Health System, Singapore, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
authors.forename: Kian Keong
authors.initials: KK
authors.lastname: Poh
authors.affiliation: Cardiac Department, National University Heart Center, National University Health System, Singapore, Singapore.
authors.forename: Ping
authors.initials: P
authors.lastname: Chai
mesh_terms: D000465:Algorithms; D001331:Automation; D006321:Heart / Q000033:anatomy & histology*; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D008953:Models, Anatomic; D066230:Patient-Specific Modeling; D013997:Time Factors
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