title: [The effects of preparation "Histochrome" in biochemical parameters of blood for patients with cardiopathologies].
abstract: The effects of the small doses of the preparation Gistochrome, containing natural polyhydroxynaphtoquinoine echinochrom A from flat sea urchin Scaphechinus mirabilis, on blood biochemical parameters have been studied in patients with cardiovascular diseases. Gistochrome administration influenced the LPO-antioxidant protection system, indicating reinforcement of antioxidant protection mechanisms. Gistochrome modulated the immune status and the plasma cytokine profile. Thus, Gistochrome may be recommended as means of additional therapy for patients with cardiovascular diseases for correcting the metabolic, immunological and redox impairments.
authors.forename: A V
authors.initials: AV
authors.lastname: Tsybulskiĭ
authors.forename: A M
authors.initials: AM
authors.lastname: Popov
authors.forename: A A
authors.initials: AA
authors.lastname: Artiukhov
authors.forename: O N
authors.initials: ON
authors.lastname: Krivoshapko
authors.forename: É P
authors.initials: ÉP
authors.lastname: Kozlovskaia
authors.forename: L N
authors.initials: LN
authors.lastname: Bogdanovich
authors.forename: S P
authors.initials: SP
authors.lastname: Kryzhanovskiĭ
authors.forename: Iu G
authors.initials: IuG
authors.lastname: Blinov
mesh_terms: D000818:Animals; D015703:Antigens, CD / Q000378:metabolism; D000975:Antioxidants / Q000302:isolation & purification / Q000627:therapeutic use*; D050197:Atherosclerosis / Q000097:blood* / Q000188:drug therapy / Q000503:physiopathology; D001772:Blood Cell Count; D016022:Case-Control Studies; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D015243:Cholesterol, VLDL / Q000097:blood; D016207:Cytokines / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000188:drug therapy / Q000503:physiopathology; D007155:Immunologic Factors / Q000302:isolation & purification / Q000627:therapeutic use*; D007273:Injections, Intramuscular; D015227:Lipid Peroxidation / Q000187:drug effects; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood* / Q000188:drug therapy / Q000503:physiopathology; D009285:Naphthoquinones / Q000302:isolation & purification / Q000627:therapeutic use*; D010084:Oxidation-Reduction / Q000187:drug effects; D012617:Sea Urchins / Q000737:chemistry; D014280:Triglycerides / Q000097:blood
chemical_list: D015703:Antigens, CD; D000975:Antioxidants; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D015243:Cholesterol, VLDL; D016207:Cytokines; D007155:Immunologic Factors; D009285:Naphthoquinones; D014280:Triglycerides; D008315:Malondialdehyde; C007573:echinochrome A