title: Non-traumatic hypertrophic callus of the fibula mimicking osteosarcoma in osteogenesis imperfecta type V: a case report.
abstract: We report a case of hyperplastic callus mimicking osteosarcoma in the fibula of a patient with osteogenesis imperfecta type V. Among the various imaging modalities, computed tomography was the most useful in distinguishing this rare process from a malignant entity. In addition, simple radiographs demonstrated the presence of characteristic "zebra lines", a manifestation of cyclic bisphosphonate therapy during childhood.
authors.affiliation: Department of Radiology, McGill University Health Center (MUHC), Montreal, QC, H3G 1Y6, Canada.
authors.forename: Arnold
authors.initials: A
authors.lastname: Radu
authors.forename: Rene Epunza
authors.initials: RE
authors.lastname: Kanza
authors.forename: Dezso
authors.initials: D
authors.lastname: Barabas
authors.forename: Michel
authors.initials: M
authors.lastname: Lessard
authors.forename: Michel
authors.initials: M
authors.lastname: Berube
mesh_terms: D000328:Adult; D050071:Bone Density Conservation Agents / Q000009:adverse effects; D002146:Bony Callus / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D004164:Diphosphonates / Q000009:adverse effects*; D005260:Female; D005360:Fibula / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D015576:Hyperostosis / Q000139:chemically induced* / Q000000981:diagnostic imaging*; D010013:Osteogenesis Imperfecta / Q000139:chemically induced* / Q000175:diagnosis*; D012516:Osteosarcoma / Q000175:diagnosis; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates
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