title: Novel helical TiO2 nanotube arrays modified by Cu2O for enzyme-free glucose oxidation.
abstract: A helical TiO2 nanotube (TNT) array modified with cuprous oxide (Cu2O) electrode was fabricated and used for nonenzymatic glucose detection. The structure and morphology of Cu2O/TNT were characterized by X-ray diffraction and transmission electron microscopy. The electrocatalytic performance of Cu2O/TNT electrode for glucose oxidation was investigated by cyclic voltammetry and chronoamperometry. At an applied potential of +0.65 V versus SCE, a linear range was obtained within the concentration range of 3.0-9.0 mM with a detection limit of 62 μM (signal/noise=3). The response time was approximately 3 s after adding 0.10 mM glucose. Formate and gluconic acid were identified as the main products of the glucose oxidation using (1)H NMR spectrometry. A possible mechanism for continuous glucose oxidation was also proposed.
authors.affiliation: School of Chemistry and Chemical Engineering, Central South University, Changsha 410083, PR China.
authors.forename: Mei
authors.initials: M
authors.lastname: Long
authors.affiliation: School of Chemistry and Chemical Engineering, Central South University, Changsha 410083, PR China.
authors.forename: Lin
authors.initials: L
authors.lastname: Tan
authors.affiliation: School of Chemistry and Chemical Engineering, Central South University, Changsha 410083, PR China.
authors.forename: Hongtao
authors.initials: H
authors.lastname: Liu
authors.affiliation: School of Chemistry and Chemical Engineering, Central South University, Changsha 410083, PR China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: He
authors.affiliation: School of Chemistry and Chemical Engineering, Central South University, Changsha 410083, PR China. Electronic address: tangaidong@126.com.
authors.forename: Aidong
authors.initials: A
authors.lastname: Tang
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D001786:Blood Glucose / Q000032:analysis*; D003300:Copper / Q000737:chemistry*; D055664:Electrochemical Techniques / Q000295:instrumentation; D004566:Electrodes; D006801:Humans; D057230:Limit of Detection; D043942:Nanotubes / Q000737:chemistry* / Q000648:ultrastructure; D010084:Oxidation-Reduction; D014025:Titanium / Q000737:chemistry*
chemical_list: D001786:Blood Glucose; C009495:titanium dioxide; D003300:Copper; D014025:Titanium; C000520:cuprous oxide
keywords: Cu(2)O/TiO(2); Electrochemical property; Nanotube array; Sensor