title: Chiari Type I malformation yielded to the diagnosis of Crouzon syndrome.
abstract: Chiari malformation Type I (CM-I) related to syndromic craniosynostosis in pediatric patients has been well-studied. The surgical management consists of cranial vault remodeling with or without posterior fossa decompression. There were also cases, in whom CM-I was diagnosed prior to the craniosynostosis in early childhood. We present a 16-year-old boy who admitted with symptoms related to CM-I. With careful examination and further genetic investigations, a diagnosis of Crouzon syndrome was made, of which the patient and his family was unaware before. The patient underwent surgery for posterior fossa decompression and followed-up for Crouzon's syndrome. To our knowledge, this is the only case report indicating a late adolescent diagnosis of Crouzon syndrome through clinical symptoms of an associated CM-I.
authors.affiliation: Department of Neurosurgery, Taksim Training and Research Hospital, Istanbul, Turkey.
authors.forename: Aydin
authors.initials: A
authors.lastname: Canpolat
authors.affiliation: Department of Neurosurgery, Taksim Training and Research Hospital, Istanbul, Turkey.
authors.forename: Mehmet Osman
authors.initials: MO
authors.lastname: Akçakaya
authors.affiliation: Department of Neurosurgery, Taksim Training and Research Hospital, Istanbul, Turkey.
authors.forename: Emre
authors.initials: E
authors.lastname: Altunrende
authors.affiliation: Department of Neurosurgery, Taksim Training and Research Hospital, Istanbul, Turkey.
authors.forename: Harun Mehmet
authors.initials: HM
authors.lastname: Ozlü
authors.affiliation: Department of Neurosurgery, Taksim Training and Research Hospital, Istanbul, Turkey.
authors.forename: Hakan
authors.initials: H
authors.lastname: Duman
authors.affiliation: Department of Neurosurgery, Taksim Training and Research Hospital, Istanbul, Turkey.
authors.forename: Tuğrul
authors.initials: T
authors.lastname: Ton
authors.affiliation: Department of Neurosurgery, Taksim Training and Research Hospital, Istanbul, Turkey.
authors.forename: Osman
authors.initials: O
authors.lastname: Akdemir
keywords: Chiari malformation Type I; Crouzon syndrome; craniosynostosis; posterior fossa decompression
references.citation: Ophthalmology. 2005 Jun;112(6):1129-34
references.pmid: 15885794
references.citation: J Neurosurg. 1995 Oct;83(4):575-82
references.pmid: 7674004
references.citation: J Neurosurg. 2002 Aug;97(2):396-400
references.pmid: 12186468
references.citation: Neurosurg Focus. 2011 Sep;31(3):E2
references.pmid: 21882907
references.citation: Childs Nerv Syst. 2010 Jun;26(6):771-4
references.pmid: 20013282
references.citation: J Neurosurg Pediatr. 2012 Feb;9(2):111-5
references.pmid: 22295912
references.citation: J Maxillofac Oral Surg. 2009 Mar;8(1):74-6
references.pmid: 23139476
references.citation: J Neurosurg Pediatr. 2013 Mar;11(3):296-301
references.pmid: 23240845
references.citation: Neurosurgery. 1998 Jan;42(1):66-71; discussion 71-3
references.pmid: 9442505