title: Aura status: a not so frequent aura.
abstract: BACKGROUND
  Migraine aura status is a variety of migraine aura with unvalidated research criteria.
  
  
  OBJECTIVE
  We conducted a systematic review of published cases and a retrospective analysis of 500 cases of migraine with aura to evaluate the applicability and clinical features of ICHD-III beta criteria, compared to a more liberal definition for its diagnosis: ≥3 aura episodes for up to three consecutive days.
  
  
  RESULTS
  Many publications under this title correspond to persistent or formerly designated prolonged auras. Nine cases fulfilled ICHD-III beta status criteria. In our series, either 1.7% or 4.2% cases fulfilled ICDH-III beta or our definition, respectively. Regardless of the criteria, aura status patients were older at onset of status than those with typical aura, had a predominance of visual symptoms, normal neuroimaging and no sequelae. Status recurred in a few.
  
  
  CONCLUSIONS
  Both criteria identify a similar population in terms of age, gender, main symptoms, imaging and outcome. Since patients with closely recurring auras might raise the same approach independently of the criteria, the use of more liberal criteria will allow more cases for detailed diagnosis and therapeutic analysis, eventually leading to the identification of subtypes.
authors.affiliation: Department of Clinical Neurosciences, Instituto de Medicina Molecular (IMM), Faculty of Medicine (IMM) University of Lisbon, Portugal.
authors.forename: Ana Alagoa
authors.initials: AA
authors.lastname: João
authors.affiliation: Max Planck Institute for Human Cognitive and Brain Sciences, Department of Neuropsychology, Germany Berlin School of Mind and Brain, Humboldt University, Germany.
authors.forename: Tomas B
authors.initials: TB
authors.lastname: Goucha
authors.affiliation: Department of Clinical Neurosciences, Instituto de Medicina Molecular (IMM), Faculty of Medicine (IMM) University of Lisbon, Portugal Isabel_Martins@fm.ul.pt.
authors.forename: Isabel P
authors.initials: IP
authors.lastname: Martins
mesh_terms: D006801:Humans; D020325:Migraine with Aura / Q000145:classification* / Q000175:diagnosis* / Q000453:epidemiology*; D012189:Retrospective Studies
keywords: ICHD-III beta; Migraine aura status; headache classification; migraine diagnosis