title: Review of foot tumors seen in a university tumor institute.
abstract: Most tumors of the foot and ankle will be benign, and it has been easy for clinicians to underestimate the malignant potential of a given tumor. The purpose of our study was to gain insight into the incidence of different tumor types diagnosed in patients with tumors of the foot and/or ankle treated at the Rizzoli Institute from September 1990 to December 2007. Our series included 1170 patients and 1170 lesions, with an overall mean age at diagnosis of 43 (range 5 to 81) years. Overall, 870 lesions (74.36%) were nonmalignant and 300 (25.65%) were malignant. Soft tissue lesions were diagnosed in 189 patients (16.15%), of which 91 (48.15%) were nonmalignant (pseudotumors or benign). Bone lesions were diagnosed in 981 patients (83.85%), of which 779 (79.41%) were nonmalignant. Epidemiologic knowledge of foot abnormalities and clinical suspicion, an organized diagnostic method, and evidence-based treatment of musculoskeletal tumors are essential elements to obtaining optimal results in the treatment of malignant foot tumors.
authors.affiliation: Department of Orthopedics, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy. Electronic address: pietro.ruggieri@ior.it.
authors.forename: Pietro
authors.initials: P
authors.lastname: Ruggieri
authors.affiliation: Department of Orthopedics, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Angelini
authors.affiliation: Department of Orthopedics, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy.
authors.forename: Fernando D
authors.initials: FD
authors.lastname: Jorge
authors.affiliation: Department of Orthopedics, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Maraldi
authors.affiliation: Department of Orthopedics, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy.
authors.forename: Sandro
authors.initials: S
authors.lastname: Giannini
mesh_terms: D001859:Bone Neoplasms / Q000453:epidemiology* / Q000473:pathology; D005528:Foot; D006801:Humans; D007558:Italy / Q000453:epidemiology; D012983:Soft Tissue Neoplasms / Q000453:epidemiology* / Q000473:pathology
keywords: biopsy; carcinoma; diagnosis; foot lesion; primary bone tumor; sarcoma