title: Polysomnographic sleep characteristics of generally-anxious and healthy children assessed in the home environment.
abstract: BACKGROUND
  Using laboratory-based polysomnography (PSG) we recently provided evidence of significantly prolonged sleep onset latency (SOL) and reduced latency to rapid eye movement (REM) sleep among non-depressed children with generalized anxiety disorder (GAD) compared to healthy age-matched controls. In the current study we conducted unattended ambulatory PSG in a new sample of children with GAD and controls in order to examine sleeping characteristics in the home environment.
  
  
  METHODS
  Thirty-two children (ages of 7-11 years) including 16 children with primary GAD and 16 controls receiving no psychotropic medications were studied. The anxious group had a primary diagnosis of GAD without secondary mood disorders and controls were free of any medical or psychiatric diagnoses. All participants underwent structured diagnostic assessments and completed one night of home-based polysomnography (PSG).
  
  
  RESULTS
  Children with GAD exhibited significantly higher sleep efficiency (SE) and fewer rapid eye movement (REM) sleep periods compared to controls. Self-reported somatic arousal during the pre-sleep period was negatively correlated with the percentage of total REM sleep among controls, but positively correlated with REM sleep percentage in the GAD group.
  
  
  CONCLUSIONS
  A small sample size and one night of PSG only.
  
  
  CONCLUSIONS
  Home-based PSG recording do not provide evidence of disrupted sleep patterns in children with GAD. Contextual factors that better elucidate differences between laboratory and home-based sleep findings are suggested as important directions for future research.
authors.affiliation: Department of Psychology, University of Houston, 126 Heyne Building, Houston, TX 77204, United States.
authors.forename: Michelle A
authors.initials: MA
authors.lastname: Patriquin
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Howard University, United States.
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Mellman
authors.affiliation: Baylor College of Medicine, The Departments of Pediatrics and Neurology, United States; The Texas Children׳s Hospital, United States.
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Glaze
authors.affiliation: Department of Psychology, University of Houston, 126 Heyne Building, Houston, TX 77204, United States. Electronic address: caalfano@uh.edu.
authors.forename: Candice A
authors.initials: CA
authors.lastname: Alfano
mesh_terms: D001008:Anxiety Disorders / Q000503:physiopathology*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D017286:Polysomnography; D012890:Sleep; D012893:Sleep Wake Disorders / Q000175:diagnosis; D012895:Sleep, REM
keywords: Children; First night effects; Generalized anxiety disorder; Polysomnography; Pre-sleep arousal; Sleep
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