title: [Clinical significance of and treatment options for increased lipoprotein(a)].
abstract: Lipoprotein(a) has been shown to be associated with an increased incidence of cardiovascular diseases for decades. However, only recent research revealed more about its physiological function and its role in the development of cardiovascular diseases. The authors summarize the physiological role of lipoprotein(a), causes and treatment of elevated lipoprotein(a) level, and the association between lipoprotein(a) and cardiovascular diseases.
authors.affiliation: Debreceni Egyetem, Általános Orvostudományi Kar, Belgyógyászati Intézet Anyagcsere Betegségek Tanszék Debrecen Nagyerdei krt. 98. 4032.
authors.forename: Noémi
authors.initials: N
authors.lastname: Zsíros
authors.affiliation: Debreceni Egyetem, Általános Orvostudományi Kar, Belgyógyászati Intézet Anyagcsere Betegségek Tanszék Debrecen Nagyerdei krt. 98. 4032.
authors.forename: György
authors.initials: G
authors.lastname: Paragh
authors.affiliation: Debreceni Egyetem, Általános Orvostudományi Kar, Belgyógyászati Intézet Anyagcsere Betegségek Tanszék Debrecen Nagyerdei krt. 98. 4032.
authors.forename: Mariann
authors.initials: M
authors.lastname: Harangi
mesh_terms: D001241:Aspirin / Q000627:therapeutic use; D015415:Biomarkers / Q000097:blood; D001781:Blood Component Removal; D002318:Cardiovascular Diseases / Q000097:blood / Q000209:etiology*; D002352:Carrier Proteins / Q000037:antagonists & inhibitors; D053480:Cholesterol Ester Transfer Proteins / Q000037:antagonists & inhibitors; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D006951:Hyperlipoproteinemias / Q000097:blood / Q000150:complications* / Q000628:therapy; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D017270:Lipoprotein(a) / Q000097:blood* / Q000235:genetics; D009525:Niacin / Q000627:therapeutic use; D009841:Oligonucleotides / Q000627:therapeutic use; D000071449:Proprotein Convertase 9; D043484:Proprotein Convertases / Q000037:antagonists & inhibitors; D012307:Risk Factors; D012697:Serine Endopeptidases
chemical_list: D015415:Biomarkers; C506642:CETP protein, human; D002352:Carrier Proteins; D053480:Cholesterol Ester Transfer Proteins; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D000960:Hypolipidemic Agents; D017270:Lipoprotein(a); D009841:Oligonucleotides; C106092:microsomal triglyceride transfer protein; D009525:Niacin; C524142:mipomersen; C472125:PCSK9 protein, human; D000071449:Proprotein Convertase 9; D043484:Proprotein Convertases; D012697:Serine Endopeptidases; D001241:Aspirin
keywords: LPA gene; LPA gén; Lp(a); aferézis; apheresis; cardiovascular diseases; cardiovascularis betegségek