title: Platelet/lymphocyte ratio and risk of in-hospital mortality in patients with ST-elevated myocardial infarction.
abstract: BACKGROUND
  Platelet-to-lymphocyte ratio (PLR) is a new prognostic marker in coronary artery disease. We aimed to evaluate the relationship between PLR and in-hospital mortality in patients with ST-elevated acute myocardial infarction (AMI).
  
  
  METHODS
  The present study included 636 patients with ST-elevated AMI. The study population was divided into tertiles based on their admission PLR. Patients having values in the third tertile was defined as the high PLR group (n=212) and those having values in the lower 2 tertiles were defined as the low PLR group (n=424).
  
  
  RESULTS
  Risk factors of coronary artery disease and treatments administered during the in-hospital period were similar between the groups. Male patient ratio was found to be lower in the high PLR group (73% vs. 82.8%, p=0.004). In-hospital mortality was increased in the high PLR group when compared to the low PLR group (12.7% vs. 5.9%, p=0.004). The PLR >144 was found to be an independent predictor of in-hospital cardiovascular mortality (HR: 2.16, 95% CI: 1.16-4.0, p=0.014).
  
  
  CONCLUSIONS
  This study showed that PLR is an independent predictor of cardiovascular mortality in patients with ST-elevated AMI.
authors.affiliation: Department of Cardiology, Çanakkale Onsekiz Mart University, Çanakkale, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Temiz
authors.affiliation: Department of Cardiology, Çanakkale Onsekiz Mart University, Canakkale, Turkey.
authors.forename: Emine
authors.initials: E
authors.lastname: Gazi
authors.affiliation: Departmentof Cardiology, Çanakkale State Hospital, Çanakkale, Turkey.
authors.forename: Ömer
authors.initials: Ö
authors.lastname: Güngör
authors.affiliation: Department of Cardiology, Çanakkale Onsekiz Mart University, Çanakkale, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Barutçu
authors.affiliation: Department of Cardiology, Çanakkale Onsekiz Mart University, Çanakkale, Turkey.
authors.forename: Burak
authors.initials: B
authors.lastname: Altun
authors.affiliation: Department of Cardiology, Çanakkale Onsekiz Mart University, Çanakkale, Turkey.
authors.forename: Adem
authors.initials: A
authors.lastname: Bekler
authors.affiliation: Departmentof Internal Medicine, Çanakkale Onsekiz Mart University, Çanakkale, Turkey.
authors.forename: Emine
authors.initials: E
authors.lastname: Binnetoğlu
authors.affiliation: Departmentof Internal Medicine, Çanakkale Onsekiz Mart University, Çanakkale, Turkey.
authors.forename: Hacer
authors.initials: H
authors.lastname: Şen
authors.affiliation: Departmentof Internal Medicine, Çanakkale Onsekiz Mart University, Çanakkale, Turkey.
authors.forename: Fahri
authors.initials: F
authors.lastname: Güneş
authors.affiliation: Departmentof Cardiology, Çanakkale State Hospital, Çanakkale, Turkey.
authors.forename: Sabri
authors.initials: S
authors.lastname: Gazi
mesh_terms: D000368:Aged; D001792:Blood Platelets / Q000473:pathology*; D004562:Electrocardiography; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008214:Lymphocytes / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000401:mortality* / Q000503:physiopathology; D012372:ROC Curve; D012307:Risk Factors
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