title: Growth of children with juvenile idiopathic arthritis.
abstract: OBJECTIVE
  To evaluate the growth pattern in children with juvenile idiopathic arthritis and its subtypes in comparison with age, sex and temporally matched controls.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  Pediatric rheumatology clinic of a tertiary care hospital in Eastern part of India.
  
  
  METHODS
  Seventy-five children (2-12 years) diagnosed as juvenile idiopathic erthritis by International League of Associations for Rheumatology criteria and 75 age- and sex- matched controls.
  
  
  METHODS
  Weight, height and body mass index were recorded at six monthly interval in both groups over a period of 3 years.
  
  
  METHODS
  weight, height and body mass index.
  
  
  RESULTS
  Subtype distribution of juvenile idiopathic arthritis was: oligoarthritis (49%, n=37), rheumatoid factor negative polyarthritis (27%, n=20), rheumatoid factor positive polyarthritis (8%, n=6), systemic onset (15%, n=11) and enthesitis related arthritis (1.3%, n=1). Anthropometric parameters in children with juvenile idiopathic arthritis were not significant different from controls. Comparison between the subtypes showed significant differences in height (P=0.011), weight (P=0.005), and growth velocity (P=0.005), but not in body mass index. Systemic onset disease led to significant restriction in height (P=0.018; 95% CI 2.13-33.77) and weight (P=0.008; 95% CI 1.47-14.43) compared to controls. Growth velocity was significantly affected in rheumatoid factor positive polyarthritis (P=0.003; 95% CIO. 46-3.14).
  
  
  CONCLUSIONS
  Children with juvenile idiopathic arthritis do not have significantly lower values of anthropometric parameters compared to controls. Significant restriction in height and weight is seen in systemic onset disease, and growth velocity is significantly reduced in rheumatoid factor positive subjects.
authors.affiliation: Division of Pediatric Rheumatology, Department of Pediatric Medicine, *Department of Pharmacology and #Department of Physiology, IPGMER Kolkata. Correspondence to: Dr Rakesh Mondal, Balarampur, Mahestala (PO), Kolkata 700 141, India. ivanrakesh2001@gmail.com.
authors.forename: Rakesh
authors.initials: R
authors.lastname: Mondal
authors.forename: Sumantra
authors.initials: S
authors.lastname: Sarkar
authors.forename: Niloy Kumar
authors.initials: NK
authors.lastname: Das
authors.forename: Swati
authors.initials: S
authors.lastname: Chakravorti
authors.forename: Avijit
authors.initials: A
authors.lastname: Hazra
authors.forename: Tapas
authors.initials: T
authors.lastname: Sabui
authors.forename: Madhumita
authors.initials: M
authors.lastname: Nandi
authors.forename: Biman
authors.initials: B
authors.lastname: Ray
authors.forename: Anjan
authors.initials: A
authors.lastname: Das
authors.forename: Sushas
authors.initials: S
authors.lastname: Ganguli
mesh_terms: D001171:Arthritis, Juvenile / Q000453:epidemiology*; D001827:Body Height / Q000502:physiology*; D001835:Body Weight / Q000502:physiology*; D016022:Case-Control Studies; D002648:Child; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male