title: Characteristics of harmonic indexes of the arterial blood pressure waveform in polycystic ovary syndrome.
abstract: BACKGROUND
  Patients with polycystic ovary syndrome (PCOS; which is often associated with increased cardiovascular risk factors) may present hemodynamic changes in the cardiovascular system. The aim of the present study was to verify whether harmonic indexes of the arterial blood pressure waveform (BPWs) can be used to discriminate between PCOS patients and healthy individuals.
  
  
  METHODS
  Twenty-minute bilateral radial BPW signals were obtained in 20 PCOS patients and 20 healthy individuals. Amplitude proportions (Cn values) and their coefficients of variation (CVn values) were calculated for harmonics 1-10 of the BPW.
  
  
  RESULTS
  C1 was significantly larger whereas C4, CV2, and CV6 were significantly smaller in PCOS patients compared with healthy individuals.
  
  
  CONCLUSIONS
  The results of the present study suggest that harmonic-analysis indexes of the BPWs could provide information about the arterial pulse transmission (by monitoring Cn) and cardiovascular regulatory activities (by monitoring CVn). These findings could aid the development of an easy-to-perform, noninvasive, and continuous monitoring technique to improve the detection of PCOS-induced hemodynamic changes.
authors.affiliation: aGraduate Institute of Applied Science and Technology bGraduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology Departments of cTraditional Chinese Medicine dObstetrics and Gynecology, Taipei City Hospital RenAi Branch, Taipei, Taiwan.
authors.forename: Chia-Liang
authors.initials: CL
authors.lastname: Hsu
authors.forename: Hsin
authors.initials: H
authors.lastname: Hsiu
authors.forename: Wei-Chen
authors.initials: WC
authors.lastname: Hsu
authors.forename: Chih-Yu
authors.initials: CY
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D001794:Blood Pressure; D005260:Female; D006801:Humans; D008955:Models, Cardiovascular; D011085:Polycystic Ovary Syndrome / Q000503:physiopathology*; D063177:Pulse Wave Analysis