title: Electrophoretic deposition of cellulose nanocrystals (CNs) and CNs/alginate nanocomposite coatings and free standing membranes.
abstract: This study presents the electrophoretic deposition (EPD) of cellulose nanocrystals (CNs) and CNs-based alginate composite coatings for biomedical applications. The mechanism of anodic deposition of CNs and co-deposition of CNs/alginate composites was analyzed based on the results of zeta-potential, Fourier transform infrared spectroscopy and scanning electron microscopy (SEM) analyses. The capability of the EPD technique for manipulating the orientation of CNs and for the preparation of multilayer CNs coatings was demonstrated. The nanotopographic surface roughness and hydrophilicity of the deposited coatings were measured and discussed. Electrochemical testing demonstrated that a significant degree of corrosion protection of stainless steel could be achieved when CNs-containing coatings were present. Additionally, the one-step EPD-based processing of free-standing CNs/alginate membranes was demonstrated confirming the versatility of EPD to fabricate free-standing membrane structures compared to a layer-by-layer deposition technique. CNs and CNs/alginate nanocomposite coatings produced by EPD are potential candidates for biomedical, cell technology and drug delivery applications.
authors.affiliation: Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Cauerstrasse 6, 91058 Erlangen, Germany.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Chen
authors.affiliation: CEMITEC, Materials Department, Polígono Mocholí, Plaza Cein 4, 31110 Noain, Navarra, Spain.
authors.forename: Uxua Pérez
authors.initials: UP
authors.lastname: de Larraya
authors.affiliation: CEMITEC, Materials Department, Polígono Mocholí, Plaza Cein 4, 31110 Noain, Navarra, Spain.
authors.forename: Nere
authors.initials: N
authors.lastname: Garmendia
authors.affiliation: CEMITEC, Materials Department, Polígono Mocholí, Plaza Cein 4, 31110 Noain, Navarra, Spain.
authors.forename: María
authors.initials: M
authors.lastname: Lasheras-Zubiate
authors.affiliation: Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Cauerstrasse 6, 91058 Erlangen, Germany.
authors.forename: Luis
authors.initials: L
authors.lastname: Cordero-Arias
authors.affiliation: Institute for Surface Science and Corrosion, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Martensstrasse7, 91058 Erlangen, Germany.
authors.forename: Sannakaisa
authors.initials: S
authors.lastname: Virtanen
authors.affiliation: Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Cauerstrasse 6, 91058 Erlangen, Germany. Electronic address: aldo.boccaccini@ww.uni-erlangen.de.
authors.forename: Aldo R
authors.initials: AR
authors.lastname: Boccaccini
mesh_terms: D000464:Alginates / Q000737:chemistry*; D002482:Cellulose / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D003343:Corrosion; D004586:Electrophoresis / Q000379:methods*; D020723:Glucuronic Acid / Q000737:chemistry; D006603:Hexuronic Acids / Q000737:chemistry; D008567:Membranes, Artificial; D053761:Nanocomposites / Q000737:chemistry* / Q000648:ultrastructure; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D017550:Spectroscopy, Fourier Transform Infrared; D014867:Water / Q000737:chemistry; D017155:Wettability
chemical_list: D000464:Alginates; D020099:Coated Materials, Biocompatible; D006603:Hexuronic Acids; D008567:Membranes, Artificial; D014867:Water; D020723:Glucuronic Acid; D002482:Cellulose
keywords: Alginate; Cellulose nanocrystals; Electrophoretic deposition; Multilayer coatings; Nanotopography; Polyelectrolyte membrane