title: Social correlates of total cancer in adults and the very old: UK Understanding Society Cohort, 2009-2010.
abstract: OBJECTIVE
  Understanding of the social determinants of cancer in adults and the very old is still limited. The aim of this study was to provide recent evidence on the social correlates of adult total cancer in a national and population-based setting.
  
  
  METHODS
  A cross-sectional study in the recent years between 2009 and 2010.
  
  
  METHODS
  Data was retrieved and analysed from the UK Longitudinal Household Survey. Information on demographics, living and work conditions, self-reported cancer and age of onset was obtained by household interview. Analyses included Chi-squared test, t-test, and multilevel logistic regression modelling.
  
  
  RESULTS
  Of 50,994 people included in the cohort, 1623 (3.5%) had ever cancer. Of these, 1592 (98.0%) occurred in adulthood (16y+) and only 109 people had their first cancer (incident cancer) at the age when they were interviewed. In the middle-aged and young adults, being female (OR 1.57, 95%CI 1.20-2.06, P = 0.001 and OR 2.04, 95%CI 1.07-3.87, P = 0.03, respectively), not born in the UK (OR 0.54, 95%CI 0.34-0.88, P = 0.01 and OR 0.31, 95%CI 0.09-1.02, P = 0.05, respectively), and being obese/overweight (OR 1.49, 95%CI 1.07-2.07, P = 0.02 and OR 2.34, 95%CI 1.17-4.66, P = 0.02, respectively) were associated with total cancer. However, no associated social factors of cancer in the very old were found. Moreover, prevalence was higher in East Midlands (OR 1.73, 95%CI 1.00-3.00, P = 0.05) but not other regions, compared to London region.
  
  
  CONCLUSIONS
  Social environment seems to continue playing a role in the aetiology of cancer in adults, although novel and/or pooled investigation for the very old would be warranted.
authors.affiliation: School of the Built Environment, Heriot-Watt University, UK. Electronic address: i.shiue@hw.ac.uk.
authors.forename: I
authors.initials: I
authors.lastname: Shiue
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology*; D015995:Prevalence; D012307:Risk Factors; D064890:Social Determinants of Health; D012931:Social Environment; D012959:Socioeconomic Factors; D006113:United Kingdom / Q000453:epidemiology; D055815:Young Adult
keywords: Cancer; Epidemiology; Population health; Prevention; Social determinants