title: Efficient Bayesian-based multiview deconvolution.
abstract: Light-sheet fluorescence microscopy is able to image large specimens with high resolution by capturing the samples from multiple angles. Multiview deconvolution can substantially improve the resolution and contrast of the images, but its application has been limited owing to the large size of the data sets. Here we present a Bayesian-based derivation of multiview deconvolution that drastically improves the convergence time, and we provide a fast implementation using graphics hardware.
authors.affiliation: 1] Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany. [2] Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA. [3] Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York, USA. [4] Gruss Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, New York, USA.
authors.forename: Stephan
authors.initials: S
authors.lastname: Preibisch
authors.affiliation: Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA.
authors.forename: Fernando
authors.initials: F
authors.lastname: Amat
authors.affiliation: Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
authors.forename: Evangelia
authors.initials: E
authors.lastname: Stamataki
authors.affiliation: Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
authors.forename: Mihail
authors.initials: M
authors.lastname: Sarov
authors.affiliation: 1] Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA. [2] Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York, USA. [3] Gruss Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, New York, USA.
authors.forename: Robert H
authors.initials: RH
authors.lastname: Singer
authors.affiliation: 1] Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany. [2] Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA.
authors.forename: Eugene
authors.initials: E
authors.lastname: Myers
authors.affiliation: Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
authors.forename: Pavel
authors.initials: P
authors.lastname: Tomancak
mesh_terms: D000465:Algorithms; D001499:Bayes Theorem; D007091:Image Processing, Computer-Assisted; D008856:Microscopy, Fluorescence / Q000295:instrumentation* / Q000379:methods*
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