title: Asymmetric chlorocyclization of indole-3-yl-benzamides for the construction of fused indolines.
abstract: (DHQD)2PHAL catalyzed enantioselective chlorocyclization of indole-3-yl-benzamides was realized. Fused indolines containing a continuous quaternary carbon center and tertiary carbon center were obtained in good yields with excellent enantioselectivity (up to 98% yield and >99% ee).
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Lu, Shanghai 200032, China.
authors.forename: Qin
authors.initials: Q
authors.lastname: Yin
authors.forename: Shu-Li
authors.initials: SL
authors.lastname: You
mesh_terms: D001549:Benzamides / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D001549:Benzamides; D007211:Indoles; C057812:indoline; C030374:indole