title: Severe depression masquerading as Creutzfeldt-Jakob disease.
abstract: We report a case of melancholic depression with catatonic features presenting as a rapidly progressive organic brain syndrome, initially thought to be probable Creutzfeldt-Jakob disease. The case highlights the fundamental importance of thorough exclusion of treatable pathology masquerading as an irreversible syndrome.
authors.affiliation: Institute of Neurological Sciences, Prince of Wales Hospital, Sydney, Australia.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Shiner
authors.forename: Lauren
authors.initials: L
authors.lastname: Taylor
authors.forename: Adith
authors.initials: A
authors.lastname: Mohan
authors.forename: Shaun
authors.initials: S
authors.lastname: Watson
authors.forename: Perminder Singh
authors.initials: PS
authors.lastname: Sachdev
mesh_terms: D000369:Aged, 80 and over; D002389:Catatonia / Q000175:diagnosis; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis*; D003865:Major Depressive Disorder / Q000175:diagnosis* / Q000628:therapy; D003937:Diagnosis, Differential; D004565:Electroconvulsive Therapy; D004569:Electroencephalography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D018476:Hypokinesia / Q000209:etiology; D008279:Magnetic Resonance Imaging; D014202:Tremor / Q000209:etiology
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