title: [Validation on the elimination of neonatal tetanus programs through Lot Quality Assurance-Cluster Sample Survey in China].
abstract: OBJECTIVE
  Field surveys were performed under WHO recommended validation procedures, using the Lot Quality Assurance-Cluster Sample(LQA-CS)method to validate the elimination status regarding neonatal tetanus in China.
  
  
  METHODS
  LQA-CS surveys were conducted in two areas under the highest risk of neonatal tetanus-Jiangmen prefecture in Guangdong and Hechi in Guangxi. Random sampling method was conducted on 96 survey clusters in each prefecture with 12 eligible live births(live birth born one year before the survey)for each cluster, by trained investigators.
  
  
  RESULTS
  There were 1 153 eligible live births from 23 465 families surveyed in Jiangmen and 1 152 eligible live births from 21 623 families being studied in Hechi. All the indices on quality control were strictly followed. There was no neonatal tetanus case which met the criteria of neonatal elimination found in either of the areas. Data showed that neonatal tetanus had been eliminated in both Jiangmen and Hechi cities.
  
  
  CONCLUSIONS
  Since both Jiangmen and Hechi were cities having the highest-risk in China, it was most likely that neonatal tetanus had also been eliminated in other prefectures at lower risk. Elimination programs on MNT was therefore considered validate in China when the study was carried out. However, the achievements needed to be maintained.
authors.affiliation: Capital Institute of Pediatrics, Beijing 100020, China.
authors.forename: Zhaoyang
authors.initials: Z
authors.lastname: Fan
authors.affiliation: Capital Institute of Pediatrics, Beijing 100020, China. Email: hongyanguan@126.com.
authors.forename: Hongyan
authors.initials: H
authors.lastname: Guan
authors.affiliation: Public Health School, Peking University Health Center.
authors.forename: Shusheng
authors.initials: S
authors.lastname: Luo
authors.affiliation: WHO Beijing Office.
authors.forename: Shuyan
authors.initials: S
authors.lastname: Zuo
authors.affiliation: UNICEF Beijing Office.
authors.forename: Xu
authors.initials: X
authors.lastname: Zhu
authors.affiliation: National Center for Immunization Program, Chinese Center for Disease Control and Prevention.
authors.forename: Wei
authors.initials: W
authors.lastname: Xia
authors.affiliation: National Center for Immunization Program, Chinese Center for Disease Control and Prevention.
authors.forename: Huiming
authors.initials: H
authors.lastname: Luo
authors.affiliation: Department of Maternal and Children Health Care,National Health and Family Planning Commission.
authors.forename: Xiaochao
authors.initials: X
authors.lastname: Xu
authors.affiliation: Department of Maternal and Children Health Care,National Health and Family Planning Commission.
authors.forename: Bin
authors.initials: B
authors.lastname: Cao
mesh_terms: D002681:China / Q000453:epidemiology; D006801:Humans; D007231:Infant, Newborn; D055810:Lot Quality Assurance Sampling; D013742:Tetanus / Q000453:epidemiology* / Q000517:prevention & control*