title: Acylated flavonol glycosides from the flower of Elaeagnus angustifolia L.
abstract: Seven acylated flavonol glycosides named elaeagnosides A-G, in addition to seven known flavonoids were isolated from the flowers of Elaeagnus angustifolia. Their structures were elucidated by different spectroscopic methods including 1D, 2D NMR experiments and HR-ESI-MS analysis. In order to identify natural antioxidant and tyrosinase inhibitor agents, the abilities of these flavonoids to scavenge the 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and to inhibit tyrosinase activity were evaluated. Results revealed that two of these compounds had significant anti-oxidant effect and one compound showed weak tyrosinase-inhibitory activity compared with kojic acid, quercetin, or ascorbic acid, which were used as positive control.
authors.affiliation: Groupe Isolement et Structure, Institut de Chimie Moléculaire de Reims (ICMR), CNRS UMR 7312, UFR de Pharmacie, BP 1039, 51687 Reims, France.
authors.forename: Sarah
authors.initials: S
authors.lastname: Bendaikha
authors.affiliation: Groupe Isolement et Structure, Institut de Chimie Moléculaire de Reims (ICMR), CNRS UMR 7312, UFR de Pharmacie, BP 1039, 51687 Reims, France.
authors.forename: Méredith
authors.initials: M
authors.lastname: Gadaut
authors.affiliation: Service Commun d'Analyses, Institut de Chimie Moléculaire de Reims (ICMR), CNRS UMR 7312, Bat. 18, BP 1039, 51687 Reims Cedex 2, France.
authors.forename: Dominique
authors.initials: D
authors.lastname: Harakat
authors.affiliation: Groupe Isolement et Structure, Institut de Chimie Moléculaire de Reims (ICMR), CNRS UMR 7312, UFR de Pharmacie, BP 1039, 51687 Reims, France. Electronic address: abdulmagid.alabdulmagid@univ-reims.fr.
authors.forename: Alabdul
authors.initials: A
authors.lastname: Magid
mesh_terms: D000215:Acylation; D000975:Antioxidants / Q000737:chemistry; D031263:Elaeagnaceae / Q000737:chemistry*; D044948:Flavonols / Q000737:chemistry*; D035264:Flowers / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D014442:Monophenol Monooxygenase / Q000037:antagonists & inhibitors
chemical_list: D000975:Antioxidants; D044948:Flavonols; D006027:Glycosides; D014442:Monophenol Monooxygenase
keywords: DPPH free radical scavenging activity; Elaeagnaceae; Elaeagnus angustifolia L.; Flavonoids; Tyrosinase inhibitory activity