title: Effects of soybean oligosaccharides on antioxidant enzyme activities and insulin resistance in pregnant women with gestational diabetes mellitus.
abstract: The effects of soybean oligosaccharides (SBOS) on antioxidant enzyme activities and insulin resistance in pregnant women with gestational diabetes mellitus (GDM) were investigated. Ninety-seven pregnant women with GDM were randomly divided into two groups, the control group (51 cases) and the SBOS group (46 cases). Before the group separation, the blood sugar level in patients was maintained stable by regular diet and insulin treatment. The control group was continued with the insulin treatment, while the SBOS group was treated with the combination of insulin and SBOS. Results showed that SBOS were able to reduce oxidative stress and alleviate insulin resistance in pregnant women with GDM, which indicates that SBOS may play an important role in the control of GDM complications.
authors.affiliation: Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
authors.forename: Bei-bei
authors.initials: BB
authors.lastname: Fei
authors.affiliation: Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China. Electronic address: LL680709@163.com.
authors.forename: Li
authors.initials: L
authors.lastname: Ling
authors.affiliation: Department of Emergency, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
authors.forename: Chen
authors.initials: C
authors.lastname: Hua
authors.affiliation: Clinic of Nutrition, Suzhou Municipal Hospital, Suzhou 215002, China.
authors.forename: Shu-yan
authors.initials: SY
authors.lastname: Ren
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000008:administration & dosage / Q000737:chemistry; D016640:Diabetes, Gestational / Q000097:blood / Q000178:diet therapy* / Q000201:enzymology; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D007333:Insulin Resistance; D009844:Oligosaccharides / Q000008:administration & dosage* / Q000737:chemistry; D011247:Pregnancy; D013025:Glycine max / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D007328:Insulin; D009844:Oligosaccharides
keywords: Antioxidant enzyme; Gestational diabetes mellitus; Insulin resistance; Soybean oligosaccharides