title: A facile sol-gel synthesis of impurity-free nanocrystalline titania.
abstract: This paper reports an original technique that provides a highly pure crystalline sol of titania with controllable particle size by ultrasonic activation of the hydrolysis products of titanium isopropoxide in an aqueous medium at a near-neutral pH, which is potentially promising in impurity-sensitive electronics and biochemical engineering. Optimal conditions (H2O/TIP ratio, sonication time, etc.) for preparation of stable nanocrystalline titania sol were adopted. A new mechanism of regulation of aggregation and polycondensation under ultrasonic irradiation is proposed. Entrapment of human serum albumin (HSA) in the formed porous titania matrix results in high thermal stability of the protein dopants: the denaturation temperature of HSA is shifted by 31 °C.
authors.affiliation: G.A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences, Ivanovo 153045, Russian Federation. vinogradoffs@gmail.com.
authors.forename: Alexandr V
authors.initials: AV
authors.lastname: Vinogradov
authors.forename: Al'ena V
authors.initials: AV
authors.lastname: Ermakova
authors.forename: Mikhail F
authors.initials: MF
authors.lastname: Butman
authors.forename: Evamarie
authors.initials: E
authors.lastname: Hey-Hawkins
authors.forename: Vladimir V
authors.initials: VV
authors.lastname: Vinogradov
mesh_terms: D005782:Gels / Q000138:chemical synthesis* / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D049329:Nanostructures / Q000737:chemistry*; D010316:Particle Size; D013499:Surface Properties; D013696:Temperature; D014025:Titanium / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D005782:Gels; D014867:Water; C009495:titanium dioxide; D014025:Titanium