title: Iridium-catalyzed enantioselective C-H alkylation of ferrocenes with alkenes using chiral diene ligands.
abstract: The first catalytic and enantioselective C-H alkylation of ferrocene derivatives with various alkenes was achieved. A cationic iridium complex, having a chiral diene ligand, and an isoquinolyl moiety as a directing group are essential for regioselective and enantioselective C-H bond activation.
authors.affiliation: Department of Chemistry and Biochemistry, School of Advanced Science and Engineering, Waseda University, Shinjuku, Tokyo 169-8555 (Japan) http://www.chem.waseda.ac.jp/shibata/; ACT-C, Japan Science and Technology Agency (JST), 4-1-8 Honcho Kawaguchi, Saitama, 332-0012 (Japan). tshibata@waseda.jp.
authors.forename: Takanori
authors.initials: T
authors.lastname: Shibata
authors.forename: Tsubasa
authors.initials: T
authors.lastname: Shizuno
keywords: CH activation; alkylation; enantioselectivity; iridium; synthetic methods