title: Red cell distribution width as a prognostic indicator in pediatric heart disease and after surgery.
abstract: BACKGROUND
  Red cell distribution width (RDW) is an important marker which reflects inflammatory activity in many chronic diseases. The objective of this study is to investigate the impact of RDW on morbidity and mortality before and after pediatric congenital heart surgery.
  
  
  METHODS
  107 patients with congenital heart disease, cardiac case group, and 70 patients, control group, without heart disease were retrospectively analyzed. Pre-, and postoperative and at discharge RDW of the cardiac patients were determined. Lengths of hospital and intensive care unit (ICU) stay and exited patients were determined.
  
  
  RESULTS
  Mean lengths of ICU and hospital stay were 3.3 ± 2.7 and 7.3 ± 2.9 days. In control group, mean preoperative RDW was 12.6 ± 1.4, while in cardiac case group it was significantly higher (15.1 ± 3.5). In cardiac case group, postoperative RDW were significantly higher than preoperative period, while RDW at discharge were significantly lower than postoperative estimates. A significant and a positive correlation was detected between lengths of ICU and hospital stay and RDW. RDW of the exited patients were significantly higher than the survivors.
  
  
  CONCLUSIONS
  This study demonstrates that RDW can be used as an important indicator in the prediction of morbidity and mortality during pre-, and postoperative period of the pediatric congenital heart disease surgery.
authors.affiliation: Department of Cardiovascular Surgery, Van Research and Education Hospital, 65100 Van, Turkey.
authors.forename: Vural
authors.initials: V
authors.lastname: Polat
authors.affiliation: Department of Cardiovascular Surgery, Van Research and Education Hospital, 65100 Van, Turkey.
authors.forename: Sahin
authors.initials: S
authors.lastname: Iscan
authors.affiliation: Department of Cardiovascular Surgery, Van Research and Education Hospital, 65100 Van, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Etli
authors.affiliation: Department of Cardiovascular Surgery, Van Research and Education Hospital, 65100 Van, Turkey.
authors.forename: Helin
authors.initials: H
authors.lastname: El Kılıc
authors.affiliation: Department of Cardiovascular Surgery, Van Research and Education Hospital, 65100 Van, Turkey.
authors.forename: Ozgür
authors.initials: O
authors.lastname: Gürsu
authors.affiliation: Department of Anesthesiology and Reanimation, Van Research and Education Hospital, 65100 Van, Turkey.
authors.forename: Esra
authors.initials: E
authors.lastname: Eker
authors.affiliation: Department of Cardiovascular Surgery, Van Research and Education Hospital, 65100 Van, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Ozdemir
mesh_terms: D006348:Cardiac Surgical Procedures; D002648:Child; D002675:Child, Preschool; D018572:Disease-Free Survival; D004909:Erythrocyte Indices; D005260:Female; D006330:Heart Defects, Congenital / Q000097:blood* / Q000401:mortality* / Q000601:surgery*; D006801:Humans; D007223:Infant; D008297:Male; D011184:Postoperative Period; D012189:Retrospective Studies; D015996:Survival Rate
references.citation: J Am Coll Cardiol. 2007 Jul 3;50(1):40-7
references.pmid: 17601544
references.citation: Pediatr Int. 2012 Feb;54(1):94-8
references.pmid: 21917064
references.citation: Eur J Intern Med. 2012 Oct;23(7):604-9
references.pmid: 22939804
references.citation: Eur J Heart Fail. 2009 Dec;11(12):1152-4
references.pmid: 19926598
references.citation: Rev Esp Cardiol (Engl Ed). 2012 Jul;65(7):606-12
references.pmid: 22440296
references.citation: Vasc Med. 2012 Jun;17(3):155-63
references.pmid: 22615191
references.citation: Can J Cardiol. 2013 Apr;29(4):448-51
references.pmid: 22926040
references.citation: Thromb Haemost. 2009 Sep;102(3):581-7
references.pmid: 19718480
references.citation: Crit Care Med. 2002 Apr;30(4):827-32
references.pmid: 11940753
references.citation: Am J Cardiol. 2003 Jul 15;92(2):188-93
references.pmid: 12860222
references.citation: Circulation. 2008 Jan 15;117(2):163-168
references.pmid: 18172029
references.citation: Resuscitation. 2012 Oct;83(10):1248-52
references.pmid: 22322281
references.citation: Circ J. 2013;77(2):456-61
references.pmid: 23075764
references.citation: Pediatr Cardiol. 2006 Jul-Aug;27(4):408-13
references.pmid: 16830075
references.citation: Blood. 2004 Oct 15;104(8):2565-73
references.pmid: 15205258
references.citation: J Card Fail. 2010 Mar;16(3):230-8
references.pmid: 20206898
references.citation: Arch Pathol Lab Med. 2009 Apr;133(4):628-32
references.pmid: 19391664
references.citation: Clin Nutr. 2010 Oct;29(5):600-4
references.pmid: 20334961
references.citation: Atherosclerosis. 2012 Sep;224(1):143-9
references.pmid: 22748279
references.citation: Eur J Cardiothorac Surg. 2013 Jun;43(6):1165-9
references.pmid: 23277431
references.citation: Am J Cardiol. 2011 Apr 15;107(8):1241-5
references.pmid: 21296321