title: The Vioxx® legacy: Enduring lessons from the not so distant past.
authors.affiliation: Section of Cardiology, Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada Department of Medicine, Queen's University, Kingston, Ontario, Canada. wfmcintyre@gmail.com.
authors.forename: William F
authors.initials: WF
authors.lastname: McIntyre
authors.forename: Gerald
authors.initials: G
authors.lastname: Evans
mesh_terms: D002318:Cardiovascular Diseases / Q000139:chemically induced* / Q000266:history; D052246:Cyclooxygenase 2 Inhibitors / Q000009:adverse effects* / Q000266:history; D017277:Drug Approval; D049674:History, 21st Century; D006801:Humans; D007783:Lactones / Q000009:adverse effects* / Q000266:history; D061214:Patient Safety; D018570:Risk Assessment; D056737:Safety-Based Drug Withdrawals / Q000266:history; D013450:Sulfones / Q000009:adverse effects* / Q000266:history
chemical_list: D052246:Cyclooxygenase 2 Inhibitors; D007783:Lactones; D013450:Sulfones; C116926:rofecoxib