title: Exercise Profile and Diastolic Functions Measured via Tissue Doppler Imaging of Fibromyalgia Patients.
abstract: BACKGROUND
  Our aim was to evaluate electrocardiographic and echocardiographic properties and exercise response of patients with fibromyalgia (FM).
  
  
  METHODS
  The study included 60 women with primary FM and 30 healthy individuals. Resting electrocardiography, echocardiography and exercise treadmill test were used to compare these two groups. At apical four-chamber window, samples of transmitral diastolic inflow and tissue Doppler imaging of left ventricle lateral wall were obtained. Left ventricle ejection fraction was measured via modified Simpson's method. Exercise duration, maximal exercise capacity, maximal heart rate (HR) (bpm), maximal HR (%), rate-pressure product at maximal HR (bpm × mmHg), heart rate recovery 1 (bpm), heart rate recovery 2 (bpm) and chronotropic reserve (%) values were calculated.
  
  
  RESULTS
  Resting HR and QTc values were similar in both groups. Echocardiographic measurements in both groups did not reveal statistically significant difference except left ventricle end-diastolic diameter and left atrial diameter. Parameters related to diastolic function of the left ventricle did not differ significantly in both groups. Also, there was not any significant difference between the groups for E/E' ratio and chronotropic reserve. Exercise treadmill test results were statistically similar for both groups.
  
  
  CONCLUSIONS
  Patients with FM presented a normal HR response to exercise and those patients had normal diastolic function similar to their healthy controls.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Bozok University, Yozgat, Turkey.
authors.forename: Ozlem
authors.initials: O
authors.lastname: Balbaloglu
authors.affiliation: Department of Cardiology, Faculty of Medicine, Bozok University, Yozgat, Turkey.
authors.forename: Huseyin
authors.initials: H
authors.lastname: Ede
authors.affiliation: Department of Emergency Medicine, Faculty of Medicine, Bozok University, Yozgat, Turkey.
authors.forename: Sadiye
authors.initials: S
authors.lastname: Yolcu
authors.affiliation: Department of Neurosurgery, Faculty of Medicine, Bozok University, Yozgat, Turkey.
authors.forename: Hakan
authors.initials: H
authors.lastname: Ak
authors.affiliation: Department of Neurology, Faculty of Medicine, Bozok University, Yozgat, Turkey.
authors.forename: Nermin
authors.initials: N
authors.lastname: Tanik
authors.affiliation: Department of Cardiology, Faculty of Medicine, Bozok University, Yozgat, Turkey.
authors.forename: Gulacan
authors.initials: G
authors.lastname: Tekin
keywords: Diastolic function; Echocardiography; Electrocardiography; Exercise treadmill test; Fibromyalgia
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