title: Duloxetine in the treatment of burning mouth syndrome refractory to conventional treatment: A case report.
abstract: Patients with burning mouth syndrome (BMS) report burning sensation and pain involving the tongue and oral mucosa without any apparent medical or dental cause. The pathogenesis of this syndrome remains unclear and there is currently no standard treatment. BMS is, therefore, often misdiagnosed and its management is complex. This lack of clinical expertise may result in decreased health-related quality of life and increased psychological distress among patients with BMS. The present case report involves a 77-year-old female patient with BMS refractory to conventional treatment with nerve block and medication, who was successfully treated with duloxetine. Duloxetine may become a new therapeutic option in the management of BMS.
authors.affiliation: Department of Anaesthesiology and Pain Medicine, Wonkwang University Hospital, Ik-san, Republic of Korea kydpain@hanmail.net.
authors.forename: Yeon-Dong
authors.initials: YD
authors.lastname: Kim
authors.affiliation: Department of Anaesthesiology and Pain Medicine, Chonbuk National University Hospital, Jeon-ju, Republic of Korea.
authors.forename: Ji-Hye
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Department of Anaesthesiology and Pain Medicine, Wonkwang University Hospital, Ik-san, Republic of Korea.
authors.forename: Jee-Hoon
authors.initials: JH
authors.lastname: Shim
mesh_terms: D000368:Aged; D000700:Analgesics / Q000627:therapeutic use*; D002054:Burning Mouth Syndrome / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology; D000068736:Duloxetine Hydrochloride / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000627:therapeutic use; D008036:Lingual Nerve / Q000187:drug effects / Q000503:physiopathology; D009407:Nerve Block / Q000379:methods; D010146:Pain / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology; D011788:Quality of Life; D013233:Stellate Ganglion / Q000187:drug effects / Q000503:physiopathology; D016896:Treatment Outcome; D014221:Triamcinolone / Q000627:therapeutic use
chemical_list: D000700:Analgesics; D014221:Triamcinolone; D000068736:Duloxetine Hydrochloride; D008012:Lidocaine
keywords: Burning mouth syndrome; duloxetine; nerve block