title: [Prenatal ultrasonic manifestation and clinical significance of fetal hemivertebra].
abstract: OBJECTIVE
  To explore the manifestation and clinical significance of prenatal ultrasound diagnosis of fetal hemivertebra.
  
  
  METHODS
  In the study, 27 fetals with hemivertebras (proven by post-natal X-ray, CT or MR) were examined by prenatal ultrasound and MR in Women & Children's Hospital, Ningbo, Zhejiang. Two-dimensional and three-dimensional prenatal ultrasonic manifestations were retrospective analyzed and compared with the prenatal MR diagnoses, the post-natal X-ray, CT, MR examinations. All the fetuses were carried out karyotype examinations. The full-term births recieved surgical treatment and the Cobb angle correction rate was calculated.
  
  
  RESULTS
  The 27 cases of fetal ultrasound showed the morphological changes of the spine, with the involved segment only half of the vertebra, in which 9 cases were single hemivertebra and 18 cases multiple, 8 cases were no malformation and 19 cases other malformations, and 19 cases were induction of labor, and 8 cases of term delivery. Compared with postpartum X-ray and other imaging tests, the prenatal ultrasound accuracy rate was 92.5%, and prenatal MR 96.3%. In the 27 cases, the chromosome cultures of 25 cases were successful, in which the normal karyotype was 68.0% (17/25), and abnormal karyotype 32.0% (8/25) with multiple hemivertebra accounting for 47.1% (8/17). In 8 cases with posterior approach of hemivertebra resection, 6 patients were less than and equal to 3 years old, whose average Cobb angle correction rate was 38.02%, and 2 more than 3 years old, whose average Cobb angle correction rate was 24.98%.
  
  
  CONCLUSIONS
  Fetal hemivertebra have typical sonographic manifestations. In diagnosis of fetal hemivertebra, the accuracy of prenatal ultrasound is close to that of MR, which has important clinical implications in diagnosis and overall assessment of fetal hemivertebra, and can also provide appropriate clinical genetic reference.
authors.affiliation: Department of Ultrasonography, Women & Children's Hospital, Zhejiang Ningbo 315010, China.
authors.forename: Han-min
authors.initials: HM
authors.lastname: Zhang
authors.affiliation: Department of Ultrasonography, Women & Children's Hospital, Zhejiang Ningbo 315010, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Hu
authors.affiliation: Department of Ultrasonography, Women & Children's Hospital, Zhejiang Ningbo 315010, China.
authors.forename: Xia
authors.initials: X
authors.lastname: Lin
authors.affiliation: Department of Ultrasonography, Women & Children's Hospital, Zhejiang Ningbo 315010, China.
authors.forename: Qing-ming
authors.initials: QM
authors.lastname: Fu
authors.affiliation: Department of Ultrasonography, Women & Children's Hospital, Zhejiang Ningbo 315010, China.
authors.forename: Bi-hua
authors.initials: BH
authors.lastname: Zhou
authors.affiliation: Department of Ultrasonography, Women & Children's Hospital, Zhejiang Ningbo 315010, China.
authors.forename: Zhi-nan
authors.initials: ZN
authors.lastname: Jiang
mesh_terms: D005260:Female; D005333:Fetus; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy; D012189:Retrospective Studies; D013122:Spinal Diseases / Q000000981:diagnostic imaging*; D013131:Spine / Q000473:pathology; D016216:Ultrasonography, Prenatal