title: [Association of cardiovascular system and endothelial dysfunction indicators in patients with hemorrhagic shock].
abstract: Endothelial dysfunction is a universal mechanism of pathogenesis of many critical conditions. Goal of the study was to assess a relation of cardiovascular system and endothelial dysfunction indicators in patients with hemorrhagic shock.
  
  
  METHODS
  17 patients with hemorrhagic shock 3 were involved in the study. All patients received infusion therapy, artificial lung ventilation after tracheal intubation and symptomatic treatment in prehospital period. Common volume of blood loose was 2900 +/- 200 mL. The patients received infusion, transfusion, inotrope, antibacterial, respiratory and symptomatic therapy in ICU after surgical treatment. Cardio-vascular system parameters were assessed by Tischenko method of integral reography. Number of red cells, hemoglobin, lactate, endotelin-1 and Wb-factor of venous blood were studied before surgery, in 12 and in 24 hours after. Morphological study of the omentumbiopsy was carried out.
  
  
  RESULTS
  Performed correlation analysis showed statistically significant relations of cardiovascular system and endothelial dysfunction indicators in patients with hemorrhagic shock. Endothelial dysfunction occurs in patients with hemorrhagic shock 3. The endothelial dysfunction correlates with parameters of cardio-vascular system and tissue perfusion.
authors.forename: T N
authors.initials: TN
authors.lastname: Iudakova
authors.forename: A O
authors.initials: AO
authors.lastname: Girsh
authors.forename: S V
authors.initials: SV
authors.lastname: Maksimishin
authors.forename: O A
authors.initials: OA
authors.lastname: Mal'kov
mesh_terms: D000293:Adolescent; D000328:Adult; D001810:Blood Volume / Q000502:physiology; D002319:Cardiovascular System / Q000473:pathology / Q000503:physiopathology*; D004730:Endothelium, Vascular / Q000473:pathology / Q000503:physiopathology*; D004912:Erythrocytes / Q000166:cytology; D006439:Hemodynamics / Q000502:physiology*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D009852:Omentum / Q000098:blood supply; D010992:Plethysmography, Impedance; D012720:Severity of Illness Index; D012771:Shock, Hemorrhagic / Q000097:blood / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy*; D013318:Stroke Volume / Q000502:physiology; D014655:Vascular Resistance / Q000502:physiology; D055815:Young Adult
chemical_list: D006454:Hemoglobins