title: A multicomponent approach to the synthesis of N-sulfonyl β(2,3)-amino esters.
abstract: The multicomponent synthesis of α,β-disubstituted N-sulfonyl β-amino esters is described. It involves a zinc-mediated, cobalt-catalyzed three-component reaction between sulfonylimines, acrylates and organic bromides. A possible mechanism is proposed, emphasizing the intermediate formation of an organocobalt as the initiator of a Mannich-like process.
authors.affiliation: Électrochimie et Synthèse Organique, Institut de Chimie et des Matériaux Paris-Est, UMR 7182 CNRS - Université Paris-Est, 2-8 rue Henri Dunant, 94320 Thiais, France. legall@icmpe.cnrs.fr.
authors.forename: Erwan
authors.initials: E
authors.lastname: Le Gall
authors.forename: Stéphane
authors.initials: S
authors.lastname: Sengmany
authors.forename: Issa
authors.initials: I
authors.lastname: Samb
authors.forename: Sabrina
authors.initials: S
authors.lastname: Benakrour
authors.forename: Christopher
authors.initials: C
authors.lastname: Colin
authors.forename: Antoine
authors.initials: A
authors.lastname: Pignon
authors.forename: Eric
authors.initials: E
authors.lastname: Léonel