title: Colon interposition graft for corrosive esophageal stricture: midterm functional outcome.
abstract: BACKGROUND
  Corrosive esophageal stricture is a major cause of morbidity among Nigerians. In most cases, this follows accidental or parasuicidal ingestion of caustic sodium hydroxide solution (NaOH) often used in the local production of soaps. Various treatment modalities have been advocated for the treatment of esophageal stricture. In this study, we review the results of our adopted technique in the past 10 years for pedicled colonic interposition.
  
  
  METHODS
  This is a retrospective study of 21 patients who underwent substernal isoperistaltic pedicled colonic interposition graft for management of corrosive esophageal stricture. The right colon was pulled up into the neck in all the patients without resecting the strictured esophagus.
  
  
  RESULTS
  Long segment strictures and multiple strictures were the main indications for the procedure. The mean duration of the procedure was 339.6 ± 71.1 min. The average intraoperative blood loss was 673.1 ± 398.1 mL. There were two (9.5 %) hospital mortalities. Graft infarction (9.5 %), cervical fistulae (19.0 %), and reflux neo-esophagitis (14.3 %) were the main non-fatal complications. In the mid-term, dysphagia was completely relieved in a little over 84 % (16/19) of patients, while one patient (4.8 %) still experienced reflux neo-esophagitis requiring treatment. There was no case of gross regurgitation or nocturnal aspiration in the mid-term.
  
  
  CONCLUSIONS
  Although the use of pedicled colonic interposition graft offers a good mid-term functional outcome with relief of dysphagia, early postoperative morbidity is high. Graft infarction is the single most important factor for poor functional outcome and every effort must be made to prevent its occurrence.
authors.affiliation: Division of Cardiothoracic Surgery, National Cardiothoracic Center, University of Nigeria Teaching Hospital, Ituku-Ozalla, PMB 01129, Enugu, 400001, Nigeria, ndubueze.ezemba@unn.edu.ng.
authors.forename: Ndubueze
authors.initials: N
authors.lastname: Ezemba
authors.forename: John C
authors.initials: JC
authors.lastname: Eze
authors.forename: Ikechukwu A
authors.initials: IA
authors.lastname: Nwafor
authors.forename: Kenneth C
authors.initials: KC
authors.lastname: Etukokwu
authors.forename: Obinna I
authors.initials: OI
authors.lastname: Orakwe
mesh_terms: D000293:Adolescent; D000328:Adult; D016063:Blood Loss, Surgical; D002057:Burns, Chemical / Q000150:complications / Q000601:surgery*; D002424:Caustics / Q000633:toxicity; D002648:Child; D002675:Child, Preschool; D003106:Colon / Q000637:transplantation*; D003680:Deglutition Disorders / Q000139:chemically induced / Q000601:surgery; D004940:Esophageal Stenosis / Q000139:chemically induced / Q000601:surgery*; D004942:Esophagitis, Peptic / Q000209:etiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D011183:Postoperative Complications / Q000209:etiology*; D012189:Retrospective Studies; D012972:Sodium Hydroxide / Q000633:toxicity; D055815:Young Adult
chemical_list: D002424:Caustics; D012972:Sodium Hydroxide
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