title: Central nervous system involvement in primary Sjogren`s syndrome manifesting as multiple sclerosis.
abstract: Central nervous system symptoms in patients with primary Sjogren`s syndrome are rare. They can present as extraglandular manifestations and require a differential diagnosis from multiple sclerosis. Due to a variety of presentations, Sjogren`s syndrome with neurologic involvement may be difficult to diagnose. Here, we report a case of a 75-year-old woman who was first diagnosed with multiple sclerosis in 2010, but who was subsequently diagnosed with primary Sjogren`s syndrome 2 years later after showing signs of atypical neurologic manifestations. Therefore, primary Sjogren`s syndrome should be suspected in patients who present with atypical clinical and radiologic neurologic manifestations.
authors.affiliation: Department of Neurology, The First Hospital, Jilin University, Changchun, China.
authors.forename: Jing-Yao
authors.initials: JY
authors.lastname: Liu
authors.forename: Teng
authors.initials: T
authors.lastname: Zhao
authors.forename: Chun-Kui
authors.initials: CK
authors.lastname: Zhou
mesh_terms: D000368:Aged; D002490:Central Nervous System / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis / Q000503:physiopathology*; D012859:Sjogren's Syndrome / Q000175:diagnosis* / Q000503:physiopathology