title: Novel tartrate-derived guanidine-catalyzed highly enantio- and diastereoselective Michael addition of 3-substituted oxindoles to nitroolefins.
abstract: The Michael addition of 3-substituted oxindoles to nitroolefins was catalyzed by a novel tartrate-derived guanidine in high yield with excellent diastereo- and enantioselectivity. This method showed an extraordinarily broad substrate scope in terms of both reaction partners.
authors.affiliation: State Key Laboratory of Fine Chemicals, School of Pharmaceutical Science and Technology, Dalian University of Technology, Dalian 116024, P. R. China. bmwang@dlut.edu.cn.
authors.forename: Liwei
authors.initials: L
authors.lastname: Zou
authors.forename: Xiaoze
authors.initials: X
authors.lastname: Bao
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Ma
authors.forename: Yuming
authors.initials: Y
authors.lastname: Song
authors.forename: Jingping
authors.initials: J
authors.lastname: Qu
authors.forename: Baomin
authors.initials: B
authors.lastname: Wang
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D019791:Guanidine / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D009574:Nitro Compounds / Q000737:chemistry*; D000078183:Oxindoles; D013237:Stereoisomerism; D013379:Substrate Specificity; D013644:Tartrates / Q000737:chemistry*
chemical_list: D000475:Alkenes; D007211:Indoles; D009574:Nitro Compounds; D000078183:Oxindoles; D013644:Tartrates; C022960:2-oxindole; D019791:Guanidine