title: 5,10-Methylene-tetrahydrofolate dissociates into tetrahydrofolate and formaldehyde at physiological pH and acidic pH, typical conditions used during sample extraction and LC-MS/MS analysis of biological samples.
authors.affiliation: Department of Food Science, Swedish University of Agricultural Sciences (SLU), PO Box 7051, SE-750 07, Uppsala, Sweden.
authors.forename: Margaretha
authors.initials: M
authors.lastname: Jägerstad
authors.forename: Jelena
authors.initials: J
authors.lastname: Jastrebova
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D003106:Colon / Q000473:pathology*; D015179:Colorectal Neoplasms / Q000737:chemistry* / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D012007:Rectum / Q000473:pathology*; D053719:Tandem Mass Spectrometry / Q000379:methods*; D013763:Tetrahydrofolates / Q000032:analysis*
chemical_list: D013763:Tetrahydrofolates
keywords: 5,10-CH2-H4folate; interconversion; stability