title: Virus-templated plasmonic nanoclusters with icosahedral symmetry via directed self-assembly.
abstract: The assembly of plasmonic nanoparticles with precise spatial and orientational order may lead to structures with new electromagnetic properties at optical frequencies. The directed self-assembly method presented controls the interparticle-spacing and symmetry of the resulting nanometer-sized elements in solution. The self-assembly of three-dimensional (3D), icosahedral plasmonic nanosclusters (NCs) with resonances at visible wavelengths is demonstrated experimentally. The ideal NCs consist of twelve gold (Au) nanospheres (NSs) attached to thiol groups at predefined locations on the surface of a genetically engineered cowpea mosaic virus with icosahedral symmetry. In situ dynamic light scattering (DLS) measurements confirm the NSs assembly on the virus. Transmission electron micrographs (TEM) demonstrate the ability of the self-assembly method to control the nanoscopic symmetry of the bound NSs, which reflects the icosahedral symmetry of the virus. Both, TEM and DLS show that the NCs comprise of a distribution of capsids mostly covered (i.e., 6-12 NS/capsid) with NSs. 3D finite-element simulations of aqueous suspensions of NCs reproduce the experimental bulk absorbance measurements and major features of the spectra. Simulations results show that the fully assembled NCs give rise to a 10-fold surface-averaged enhancement of the local electromagnetic field.
authors.affiliation: Center for Bio/Molecular Science and Engineering, Naval Research Laboratory, 4555 Overlook Ave., SW, Code 6900, Washington, DC, 20375, USA.
authors.forename: Jake
authors.initials: J
authors.lastname: Fontana
authors.forename: Walter J
authors.initials: WJ
authors.lastname: Dressick
authors.forename: Jamie
authors.initials: J
authors.lastname: Phelps
authors.forename: John E
authors.initials: JE
authors.lastname: Johnson
authors.forename: Ronald W
authors.initials: RW
authors.lastname: Rendell
authors.forename: Travian
authors.initials: T
authors.lastname: Sampson
authors.forename: Banahalli R
authors.initials: BR
authors.lastname: Ratna
authors.forename: Carissa M
authors.initials: CM
authors.lastname: Soto
mesh_terms: D000327:Adsorption; D003460:Crystallization / Q000379:methods; D006046:Gold / Q000737:chemistry*; D008027:Light; D008422:Materials Testing; D053768:Metal Nanoparticles / Q000737:chemistry / Q000648:ultrastructure*; D054802:Molecular Imprinting / Q000379:methods*; D053761:Nanocomposites / Q000737:chemistry / Q000648:ultrastructure*; D012542:Scattering, Radiation; D020349:Surface Plasmon Resonance / Q000379:methods*; D013499:Surface Properties; D014780:Viruses / Q000737:chemistry / Q000648:ultrastructure*
chemical_list: D006046:Gold
keywords: cowpea mosaic virus; gold nanoparticles; metafluid; metamolecule; self-assembly
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