title: Synthesis of cellulose-2,3-bis(3,5-dimethylphenylcarbamate) in an ionic liquid and its chiral separation efficiency as stationary phase.
abstract: A chiral selector of cellulose-2,3-bis(3,5-dimethylphenylcarbamate) (CBDMPC) was synthesized by reacting 3,5-dimethylphenyl isocyanate with microcrystalline cellulose dissolved in an ionic liquid of 1-allyl-3-methyl-imidazolium chloride (AMIMCl). The obtained chiral selector was effectively characterized by infrared spectroscopy, elemental analysis and 1H NMR. The selector was reacted with 3-aminopropylsilanized silica gel and the CBDMPC bonded chiral stationary phase (CSP) was obtained. Chromatographic evaluation of the prepared CSPs was conducted by high performance liquid chromatographic (HPLC) and baseline separation of three typical fungicides including hexaconazole, metalaxyl and myclobutanil was achieved using n-hexane/isopropanol as the mobile phase with a flow rate 1.0 mL/min. Experimental results also showed that AMIMCl could be recycled easily and reused in the preparation of CSPs as an effective reaction media.
authors.affiliation: College of Plant Protection, Hunan Agricultural University, Changsha 410128, China. lrq@hist.edu.cn.
authors.forename: Runqiang
authors.initials: R
authors.lastname: Liu
authors.affiliation: College of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang 453003, China. zhangyijun@hist.edu.cn.
authors.forename: Yijun
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: College of Plant Protection, Hunan Agricultural University, Changsha 410128, China. blyang2006@163.com.
authors.forename: Lianyang
authors.initials: L
authors.lastname: Bai
authors.affiliation: College of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang 453003, China. huangmingxian@hist.edu.cn.
authors.forename: Mingxian
authors.initials: M
authors.lastname: Huang
authors.affiliation: College of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang 453003, China. junchen713@hist.edu.cn.
authors.forename: Jun
authors.initials: J
authors.lastname: Chen
authors.affiliation: College of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang 453003, China. zhangyuping@hist.edu.cn.
authors.forename: Yuping
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D019840:2-Propanol / Q000737:chemistry; D000409:Alanine / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D002219:Carbamates / Q000138:chemical synthesis* / Q000737:chemistry; D002482:Cellulose / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D005659:Fungicides, Industrial / Q000737:chemistry / Q000302:isolation & purification; D006586:Hexanes / Q000737:chemistry; D052578:Ionic Liquids / Q000737:chemistry*; D009570:Nitriles / Q000737:chemistry / Q000302:isolation & purification; D013237:Stereoisomerism; D014230:Triazoles / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D002219:Carbamates; D005659:Fungicides, Industrial; D006586:Hexanes; D052578:Ionic Liquids; D009570:Nitriles; D014230:Triazoles; C028175:metalaxyl; C026385:n-hexane; D002482:Cellulose; C446685:systhane; D019840:2-Propanol; D000409:Alanine; C109691:microcrystalline cellulose; C409722:hexaconazole
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