title: Functional streams and cortical integration in the human brain.
abstract: The processing of brain information relies on the organization of neuronal networks and circuits that in the end must provide the substrate for human cognition. However, the presence of highly complex and multirelay neuronal interactions has limited our ability to disentangle the assemblies of brain systems. The present review article focuses on the latest developments to understand the architecture of functional streams of the human brain at the large-scale level. Particularly, this article presents a comprehensive framework and recent findings about how the highly modular sensory cortex, such as the visual, somatosensory, auditory, as well as motor cortex areas, connects to more parallel-organized cortical hubs in the brain's functional connectome.
authors.affiliation: Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA sepulcre@nmr.mgh.harvard.edu.
authors.forename: Jorge
authors.initials: J
authors.lastname: Sepulcre
mesh_terms: D001921:Brain / Q000502:physiology*; D003071:Cognition / Q000502:physiology; D006801:Humans; D009434:Neural Pathways / Q000502:physiology; D010465:Perception / Q000502:physiology
keywords: auditory-motor; cortical integration; functional streams; multimodal integration; multisensory; visual-motor