title: Trends in hospitalized acute myocardial infarction patients with heart failure in Korea at 1998 and 2008.
abstract: Heart failure (HF) complicating acute myocardial infarction (AMI) is common and is associated with poor clinical outcome. Limited data exist regarding the incidence and in-hospital mortality of AMI with HF (AMI-HF). We retrospectively analyzed 1,427 consecutive patients with AMI in the five major university hospitals in Korea at two time points, 1998 (n = 608) and 2008 (n = 819). Two hundred twenty eight patients (37.5%) in 1998 and 324 patients (39.5%) in 2008 of AMI patients complicated with HF (P = 0.429). AMI-HF patients in 2008 were older, had more hypertension, previous AMI, and lower systolic blood pressure than those in 1998. Regarding treatments, AMI-HF patients in 2008 received more revascularization procedures, more evidence based medical treatment and adjuvant therapy, such as mechanical ventilators, intra-aortic balloon pulsation compared to those in 1998. However, overall in-hospital mortality rates (6.4% vs 11.1%, P = 0.071) of AMI-HF patients were unchanged and still high even after propensity score matching analysis, irrespective of types of AMI and revascularization methods. In conclusion, more evidence-based medical and advanced procedural managements were applied for patients with AMI-HF in 2008 than in 1998. However the incidence and in-hospital mortality of AMI-HF patients were not significantly changed between the two time points.
authors.affiliation: Division of Cardiology, Severance Cardiovascular Hospital and Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Jong-Chan
authors.identifier: 0000-0003-0998-503X
authors.initials: JC
authors.lastname: Youn
authors.affiliation: Cardiovascular Center and Cardiology Division, Incheon St. Mary's Hospital, The Catholic University of Korea, Incheon, Korea.
authors.forename: Suk Min
authors.initials: SM
authors.lastname: Seo
authors.affiliation: Department of Biostatistics, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Hye Sun
authors.initials: HS
authors.lastname: Lee
authors.affiliation: Division of Cardiology, Severance Cardiovascular Hospital and Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Jaewon
authors.initials: J
authors.lastname: Oh
authors.affiliation: Heart Failure and Cardiac Transplantation Center, Asan Medical Center Heart Institute, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Min Seok
authors.initials: MS
authors.lastname: Kim
authors.affiliation: Cardiovascular Center and Cardiology Division, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Jin-Oh
authors.initials: JO
authors.lastname: Choi
authors.affiliation: Cardiovascular Center and Cardiovascular Research Institute, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Hae-Young
authors.initials: HY
authors.lastname: Lee
authors.affiliation: Cardiovascular Center and Cardiovascular Research Institute, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Hyun-Jai
authors.initials: HJ
authors.lastname: Cho
authors.affiliation: Division of Cardiology, Severance Cardiovascular Hospital and Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Seok-Min
authors.initials: SM
authors.lastname: Kang
authors.affiliation: Heart Failure and Cardiac Transplantation Center, Asan Medical Center Heart Institute, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Jae Joong
authors.initials: JJ
authors.lastname: Kim
authors.affiliation: Cardiovascular Center and Cardiology Division, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
authors.forename: Sang Hong
authors.initials: SH
authors.lastname: Baek
authors.affiliation: Cardiovascular Center and Cardiology Division, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Eun-Seok
authors.initials: ES
authors.lastname: Jeon
authors.affiliation: Division of Cardiovascular and Rare Diseases, Center for Biomedical Sciences, Korea National Institute of Health, Cheongwon, Korea.
authors.forename: Hyun-Young
authors.initials: HY
authors.lastname: Park
authors.affiliation: Division of Cardiovascular and Rare Diseases, Center for Biomedical Sciences, Korea National Institute of Health, Cheongwon, Korea. ; Regional Cardiovascular Disease Center, Division of Cardiology, Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea.
authors.forename: Myeong-Chan
authors.initials: MC
authors.lastname: Cho
authors.affiliation: Cardiovascular Center and Cardiovascular Research Institute, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Byung-Hee
authors.initials: BH
authors.lastname: Oh
mesh_terms: D000208:Acute Disease; D000367:Age Factors; D000368:Aged; D001794:Blood Pressure; D003710:Demography; D005260:Female; D006333:Heart Failure / Q000150:complications / Q000175:diagnosis* / Q000401:mortality; D017052:Hospital Mortality / Q000639:trends*; D006801:Humans; D006973:Hypertension / Q000150:complications; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000175:diagnosis* / Q000401:mortality; D016017:Odds Ratio; D056910:Republic of Korea; D012189:Retrospective Studies
keywords: Acute Myocardial Infarction; Heart Failure; Hospital Mortality; Temporal Trend
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