title: Engineering synergy in biotechnology.
abstract: Biotechnology is a central focus in efforts to provide sustainable solutions for the provision of fuels, chemicals and materials. On the basis of a recent open discussion, we summarize the development of this field, highlighting the distinct but complementary approaches provided by metabolic engineering and synthetic biology for the creation of efficient cell factories to convert biomass and other feedstocks to desired chemicals.
authors.affiliation: 1] Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark. [2] Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden, and the Science for Life Laboratory, Royal Institute of Technology, Solna, Sweden.
authors.forename: Jens
authors.initials: J
authors.lastname: Nielsen
authors.affiliation: ETH Zurich, Department of Biosystems Science and Engineering, Basel, Switzerland.
authors.forename: Martin
authors.initials: M
authors.lastname: Fussenegger
authors.affiliation: 1] Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark. [2] Joint Bioenergy Institute, Emeryville, California, USA, the Department of Chemical and Biomolecular Engineering and the Department of Bioengineering, University of California-Berkeley, Berkeley, California, USA, the Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA, and the Synthetic Biology Engineering Research Center (SynBERC), Berkeley, California, USA.
authors.forename: Jay
authors.initials: J
authors.lastname: Keasling
authors.affiliation: 1] Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark. [2] Department of Chemical and Biomolecular Engineering, KAIST, Daejeon, Korea.
authors.forename: Sang Yup
authors.initials: SY
authors.lastname: Lee
authors.affiliation: Department of Chemical and Biomolecular Engineering, University of California-Los Angeles, Los Angeles, California, USA.
authors.forename: James C
authors.initials: JC
authors.lastname: Liao
authors.affiliation: 1] Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. [2] Synthetic Biology Engineering Research Center (SynBERC), Cambridge, Massachusetts, USA.
authors.forename: Kristala
authors.initials: K
authors.lastname: Prather
authors.affiliation: 1] Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark. [2] Department of Bioengineering, University of California-San Diego, La Jolla, California, USA.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Palsson
mesh_terms: D018533:Biomass; D001709:Biotechnology; D060847:Metabolic Engineering
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