title: Sigmoid sinus occlusion infiltrated by inflammatory myofibroblastic tumor from mastoid.
abstract: BACKGROUND
  Inflammatory myofibroblastic tumor (IMT) and some types of immunoglobulin (Ig) G4-related disease are often involved in the spectrum of inflammatory pseudotumor (IPT) and the concept of IgG4-related IPT/IMT has recently been proposed.
  
  
  METHODS
  A 38-year-old man complained of initial symptoms of blurred vision and headache.
  
  
  RESULTS
  A tumor was found in the right mastoid, which caused occlusion of the right sigmoid sinus and intracranial hypertension. A diagnosis of IMT with IgG4+ plasma cell infiltration was established by surgical, pathological, and immunohistochemistry findings. His symptoms were completely relieved after corticosteroid therapy and no recurrence was detected during 22 months of follow-up.
  
  
  CONCLUSIONS
  A case with cerebral venous sinus infiltrated by IMTs in the head and neck has never been reported; corticosteroid therapy proved satisfactory in IMT with IgG4+ plasma cell infiltration.
authors.affiliation: Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
authors.forename: Jingye
authors.initials: J
authors.lastname: Wang
authors.forename: Zhongwu
authors.initials: Z
authors.lastname: Sun
authors.forename: Shengxia
authors.initials: S
authors.lastname: Zhuo
authors.forename: Kai
authors.initials: K
authors.lastname: Wang
mesh_terms: D000328:Adult; D001847:Bone Diseases / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D003392:Cranial Sinuses; D005938:Glucocorticoids / Q000627:therapeutic use; D006104:Granuloma, Plasma Cell / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007074:Immunoglobulin G; D019586:Intracranial Hypertension / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D008297:Male; D008416:Mastoid; D008775:Methylprednisolone / Q000627:therapeutic use
chemical_list: D005938:Glucocorticoids; D007074:Immunoglobulin G; D008775:Methylprednisolone
keywords: headache; immunoglobulin (Ig)G4-related sclerosing disease; inflammatory myofibroblastic tumor; intracranial hypertension; sigmoid sinus