title: The effect of nanosilver on pigments production by Fusarium culmorum (W. G. Sm.) Sacc.
abstract: A disk-diffusion method experiment assessed the impact of nanosilver on production of secondary metabolites (pigments) by the Fusarium culmorum fungus. Nanosilver colloidal particles in water have been obtained by the use of a method based on high voltage electric arcs between silver electrodes. The silver nanoparticles size in colloid ranged between 15 and 100 nm and 7, 35 and 70 ppm concentration. Nanosilver modifies the metabolism of the researched F. culmorum strain. Coming into contact with nanosilver colloids induces more intensive mycelia pigmentation correlated with nanosilver concentration levels. The performed analysis of metabolites indicates that under the influence of nanosilver fungi biosynthesise aurofusarin more intensively and the conversion of rubrofusarin to aurofusarin is intensified as compared to the control culture. Under the influence of nanosilver F. culmorum intensively biosynthesises an unidentified dye which shares structural features with aurofusarin but which is not produced by fungi in standard cultures.
authors.forename: Marek J
authors.initials: MJ
authors.lastname: Kasprowicz
authors.forename: Anna
authors.initials: A
authors.lastname: Gorczyca
authors.forename: Rasmus J N
authors.initials: RJ
authors.lastname: Frandsen
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology; D005670:Fusarium / Q000187:drug effects* / Q000378:metabolism*; D053758:Nanoparticles / Q000737:chemistry*; D010860:Pigments, Biological / Q000378:metabolism*; D012834:Silver / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000935:Antifungal Agents; D010860:Pigments, Biological; D012834:Silver