title: A systematic review of instruments to measure sexual functioning in patients using antipsychotics.
abstract: Sexual dysfunction is a frequent side effect of antipsychotics, but information is scant regarding the psychometric properties and clinical usefulness of currently existing questionnaires. This systematic review compares the psychometric properties and content of questionnaires for assessment of sexual functioning in patients using antipsychotics. A systematic literature search was performed using three electronic databases (PubMed, Embase, and PsycINFO) with predefined search terms. We identified six validated instruments for assessment of sexual functioning in patients using antipsychotics: the Antipsychotic Non-Neurological Side Effects Rating Scale (ANNSERS), the Arizona Sexual Experience Scale (ASEX), the Antipsychotics and Sexual Functioning Questionnaire (ASFQ), the Changes in Sexual Function Questionnaire-14 (CSFQ-14), the Nagoya Sexual Function Questionnaire (NSFQ), and the Psychotropic-Related Sexual Dysfunction Questionnaire (PRSexDQ). The ASFQ, CSFQ-14, and PRSexDQ cover all stages of sexual functioning, which makes these questionnaires preferable to the other three questionnaires described. The ASFQ and PRSexDQ are clinician-administered and ask for a change in sexual functioning related to medication. The ASFQ assesses improvement as well as deterioration of sexual functioning, and includes items about hyperprolactinemia. The CSFQ-14 is useful when self-report is desired but contains more items.
authors.affiliation: a Department of Psychiatry , University Medical Center Groningen, University of Groningen.
authors.forename: Marrit K
authors.initials: MK
authors.lastname: de Boer
authors.forename: Stynke
authors.initials: S
authors.lastname: Castelein
authors.forename: Durk
authors.initials: D
authors.lastname: Wiersma
authors.forename: Robert A
authors.initials: RA
authors.lastname: Schoevers
authors.forename: Henderikus
authors.initials: H
authors.lastname: Knegtering
mesh_terms: D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D055118:Medication Adherence / Q000523:psychology; D011594:Psychometrics / Q000706:statistics & numerical data; D011618:Psychotic Disorders / Q000188:drug therapy* / Q000523:psychology*; D015203:Reproducibility of Results; D012735:Sexual Dysfunction, Physiological / Q000139:chemically induced* / Q000145:classification / Q000175:diagnosis*; D011795:Surveys and Questionnaires
chemical_list: D014150:Antipsychotic Agents