title: Complete recovery from paraparesis in spinal cord compression due to extramedullary haemopoiesis in beta-thalassaemia by emergency radiation therapy.
abstract: Extramedullary haemopoiesis (EMH) is a complication commonly associated with beta-thalassaemia intermedia; it is frequently asymptomatic but can sometimes lead to symptomatic tumour-like masses. No guidelines or common consensus are available in literature regarding the different treatment strategies and only single cases have been reported. We describe a case of spinal cord compression due to intrathoracic EMH masses treated with combined radiotherapy and hydroxyurea.
authors.affiliation: Radiation Oncology Unit, Department of Oncology, S. Luigi Hospital, University of Turin, Orbassano, Italy.
authors.forename: M G
authors.initials: MG
authors.lastname: Ruo Redda
authors.forename: S
authors.initials: S
authors.lastname: Allis
authors.forename: A
authors.initials: A
authors.lastname: Reali
authors.forename: S
authors.initials: S
authors.lastname: Bartoncini
authors.forename: S
authors.initials: S
authors.lastname: Roggero
authors.forename: S M
authors.initials: SM
authors.lastname: Anglesio
authors.forename: A
authors.initials: A
authors.lastname: Piga
mesh_terms: D006411:Hematopoiesis, Extramedullary / Q000528:radiation effects*; D006801:Humans; D020335:Paraparesis / Q000209:etiology / Q000503:physiopathology / Q000532:radiotherapy; D011379:Prognosis; D020127:Recovery of Function; D013117:Spinal Cord Compression / Q000150:complications / Q000503:physiopathology / Q000532:radiotherapy; D017086:beta-Thalassemia / Q000150:complications / Q000503:physiopathology / Q000532:radiotherapy
keywords: extramedullary haemopoiesis; radiotherapy; spinal cord compression; thalassaemia