title: [Noma in a 4 year-old girl: a case report from Chad].
abstract: This case report describes a 4-year-old girl in Chad with noma, also called cancrum oris. This acute gangrenous stomatitis has a combined morbidity-mortality rate that can reach 70%. It occurs worldwide but is most common in sub-Saharan Africa in children aged 2 to 16 years. Its pathogenesis is uncertain, but several bacteria including Fusobacterium necrophorum, Prevotella intermedia and Pseudomonas aeruginosa may be responsible for the development of noma, which develops over the oral lesions these bacteria cause. Poverty is its most important risk factor. Due to its rapid course and high lethality, it requires emergency treatment with antibiotics, daily dressing of the lesion, and nutritional rehabilitation. Surgical removal of the remaining necrotic tissue can be followed by reconstructive procedures. Physical and speech therapy should be initiated to prevent functional complications.
authors.affiliation: Service médical base aérienne 113, BP 52, 52113 Saint-Dizier Cedex.
authors.forename: K
authors.initials: K
authors.lastname: Cocquempot
authors.affiliation: Institut de recherche biomédicale des armées, Brétigny-sur-Orge.
authors.forename: O
authors.initials: O
authors.lastname: Javaudin
authors.affiliation: Service de biologie, hôpital d'instruction des armées Sainte-Anne, Toulon.
authors.forename: P
authors.initials: P
authors.lastname: Lerasle
authors.affiliation: CMA de Calvi, 2e REP, Calvi (Corse).
authors.forename: L
authors.initials: L
authors.lastname: Aigle
mesh_terms: D002596:Chad; D002675:Child, Preschool; D005260:Female; D006801:Humans; D009625:Noma / Q000175:diagnosis / Q000188:drug therapy
keywords: Chad; antibiotherapy; cancrum oris; dental physiotherapy; necrotizing gingivitis; noma; sub-Saharan Africa