title: [Brain metastases occurring more often in colorectal carcinoma].
abstract: BACKGROUND
  Colorectal carcinoma (CRC) has a high incidence. If metastatic disease develops, the liver and lungs are the most frequently involved sites. Brain metastases are rare.
  
  
  METHODS
  We present a male patient (70 years old) with lung and liver metastases of CRC. For many years the disease was in good remission with palliative chemotherapy. He developed very acute neck pain and later also vomiting. The latter turned out to be based on the presence of brain metastases, which was soon fatal.
  
  
  CONCLUSIONS
  The incidence of CRC is rising and with it the incidence of symptomatic brain metastases in CRC. Due to the development of more effective systemic chemotherapy, survival of advanced CRC has improved, providing more time for symptomatic brain metastases to develop.
authors.affiliation: Ziekenhuis Amstelland, Amstelveen.
authors.forename: Inge M
authors.initials: IM
authors.lastname: Werter
authors.forename: Daan
authors.initials: D
authors.lastname: van der Stap
authors.forename: Frits W
authors.initials: FW
authors.lastname: Bertelsmann
authors.forename: Cees J
authors.initials: CJ
authors.lastname: van Groeningen
mesh_terms: D000368:Aged; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000453:epidemiology / Q000401:mortality / Q000556:secondary*; D015179:Colorectal Neoplasms / Q000453:epidemiology / Q000401:mortality / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D015994:Incidence; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary; D008175:Lung Neoplasms / Q000401:mortality / Q000556:secondary; D008297:Male