title: Severe Plasmodium vivax malaria complicated with acute respiratory distress syndrome: a case associated with focal autochthonous transmission in Greece.
abstract: In 2011, autochthonous Plasmodium vivax malaria emerged in a focal geographical area in Greece after importation by immigrants from the Indian subcontinent. We report the case of complicated P. vivax malaria in a previously healthy 42-year-old Greek female. The patient presented acute respiratory distress syndrome (ARDS), worsening jaundice, and thrombocytopenia after the administration of antimalarial treatment and despite a decreasing burden of parasitemia. She recovered fully after admission in the intensive care unit and support with mechanical ventilation. We discuss the risks potentially associated with the reappearance of P. vivax malaria in a previously malaria-free area.
authors.affiliation: 1 Department of Internal Medicine, Tzaneio General Hospital , Piraeus, Greece .
authors.forename: Alexandra
authors.initials: A
authors.lastname: Gougoutsi
authors.forename: Drosos E
authors.initials: DE
authors.lastname: Karageorgopoulos
authors.forename: Areti
authors.initials: A
authors.lastname: Dimitriadou
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Melas
authors.forename: Georgios
authors.initials: G
authors.lastname: Kranidiotis
authors.forename: Dionysios
authors.initials: D
authors.lastname: Voutsinas
authors.forename: Andreas
authors.initials: A
authors.lastname: Melidonis
mesh_terms: D000328:Adult; D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use*; D005260:Female; D006115:Greece; D006801:Humans; D016780:Malaria, Vivax / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000635:transmission; D018512:Parasitemia; D010966:Plasmodium vivax / Q000302:isolation & purification*; D012128:Respiratory Distress Syndrome / Q000150:complications*; D013921:Thrombocytopenia; D016896:Treatment Outcome
chemical_list: D000962:Antimalarials