title: Impact of image guided fine needle aspiration cytology in diagnosis of pediatric hepatic mass and cytohistologic concordance.
abstract: BACKGROUND
  Pediatric hepatic mass is a heterogeneous group of benign and malignant lesions. Percutaneous fine needle aspiration cytology (FNAC) can be utilized as a diagnostic modality to assess the nature of radiologically demonstrated hepatic lesions and thus facilitate individualized treatment.
  
  
  OBJECTIVE
  The objective of the present study was to determine the diagnostic accuracy of percutaneous FNAC of pediatric liver masses, a procedure that is less invasive than open biopsy.
  
  
  METHODS
  A prospective, observational study was carried out in the Department of Pathology in collaboration with Department of Pediatric surgery and Radio-diagnosis including 31 pediatric patients presenting over last two years (June 2011 to May 2013) with focal hepatic lesion on ultrasound and computed tomography (CT) scan. FNAC was carried out under image guidance and cytodiagnosis was reached after appropriate staining. By comparing with histopathology reports, diagnostic accuracy of cytology was evaluated.
  
  
  RESULTS
  Among 31 cases included in the study, 51.6% cases were cytologically benign and hemangioma was the most common benign lesion. Hepatoblastoma was the most accounted malignant tumour (12.9%). FNAC provided 94% sensitivity and 92% specificity in diagnosing benign and malignant tumours. Overall diagnostic accuracy was 93.10%. No significant complication was noted.
  
  
  CONCLUSIONS
  Percutaneous FNAC under image guidance is an effective diagnostic tool for diagnosis of primary and metastatic tumours of liver in pediatric patients.
authors.affiliation: Department of Pathology, Institute of Post-Graduate Medical Education and Research, Kolkata, West Bengal, India.
authors.forename: Chhanda
authors.initials: C
authors.lastname: Das
authors.affiliation: Department of Pathology, Institute of Post-Graduate Medical Education and Research, Kolkata, West Bengal, India.
authors.forename: Madhumita
authors.initials: M
authors.lastname: Mukhopadhyay
authors.affiliation: Department of Pediatric Surgery, Nil Ratan Sircar Medical College, Kolkata, West Bengal, India.
authors.forename: Moumita
authors.initials: M
authors.lastname: Sengupta
authors.affiliation: Department of Surgery, Bankura Sammilani Medical College, Bankura, West Bengal, India.
authors.forename: Ashis Kumar
authors.initials: AK
authors.lastname: Saha
authors.affiliation: Department of Pediatric Surgery, Nil Ratan Sircar Medical College, Kolkata, West Bengal, India.
authors.forename: Biswanath
authors.initials: B
authors.lastname: Mukhopadhyay
keywords: Histopathology; pediatric hepatic mass; percutaneous fine needle aspiration cytology
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