title: Role of subcutaneous closure in preventing wound complications after cesarean delivery with Pfannenstiel incision: a randomized clinical trial.
abstract: OBJECTIVE
  The aim of this study was to evaluate the role of suture closure of the subcutaneous tissue in preventing wound complications after cesarean section with a Pfannenstiel incision, and to investigate factors associated with wound complications.
  
  
  METHODS
  Patients undergoing cesarean delivery were randomly assigned to either suture closure or non-closure of the subcutaneous tissue. The participants were invited to two follow-up examinations at the 1st and 4th postoperative weeks for the detection of wound complications. The two main outcomes were composite wound complication and superficial wound separation. Factors associated with wound complications were analyzed using multiple logistic regression.
  
  
  RESULTS
  During the study period, a total of 361 patients (176 in the closure group, 185 in non-closure group) were analyzed. Composite wound complication occurred in 23.3% (41/176) of the closure group, and in 20% (37/185) of the non-closure group with no significant difference (P = 0.44). Wound separation occurred in 2.3% (4/176) of the closure group and 1.6% (3/185) of the non-closure group without any significant differences (P = 0.64). None of the factors were found to be associated with the rate of composite complication. The significant factors found to be associated with wound separation were subcutaneous tissue thickness of 4 cm or more (P = 0.01) and maternal diabetes mellitus (P = 0.01), however they lost their significance in multivariate analyses.
  
  
  CONCLUSIONS
  The rate of wound complications, including superficial wound separation, did not differ according to the subcutaneous closure in cesarean delivery with Pfannenstiel incision. It is not possible to predict wound complications using previously defined clinical and operative risk factors, including subcutaneous tissue thickness.
authors.forename: Aytul
authors.initials: A
authors.lastname: Corbacioglu Esmer
authors.forename: Pinar Cilesiz
authors.initials: PC
authors.lastname: Goksedef
authors.forename: Aysu
authors.initials: A
authors.lastname: Akca
authors.forename: Ozgur
authors.initials: O
authors.lastname: Akbayir
authors.forename: Hediye
authors.initials: H
authors.lastname: Dagdeviren
authors.forename: Gulden Yanik
authors.initials: GY
authors.lastname: Turan
authors.forename: Filiz
authors.initials: F
authors.lastname: Yarsilikal
mesh_terms: D000328:Adult; D002585:Cesarean Section / Q000009:adverse effects*; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006784:Hospitals, Teaching; D006801:Humans; D015994:Incidence; D011183:Postoperative Complications / Q000453:epidemiology / Q000473:pathology / Q000517:prevention & control*; D012307:Risk Factors; D016037:Single-Blind Method; D040521:Subcutaneous Tissue / Q000473:pathology / Q000601:surgery; D013529:Surgical Wound Dehiscence / Q000453:epidemiology / Q000517:prevention & control; D013537:Sutures; D014421:Turkey / Q000453:epidemiology; D058106:Wound Closure Techniques; D055815:Young Adult