title: Fertility potential in a cohort of 65 men with previously acquired undescended testes.
abstract: OBJECTIVE
  To evaluate testicular function in men with previously acquired undescended testes (AUDT) in whom spontaneous descent was awaited until puberty followed by orchiopexy in case of nondescent.
  
  
  METHODS
  Andrological evaluation including paternity, scrotal ultrasound, reproductive hormones, and semen analysis was performed in three groups: men with AUDT, healthy controls, and men with previously congenital undescended testes (CUDT).
  
  
  RESULTS
  In comparison with controls, men with AUDT more often had significantly abnormal testicular consistency, smaller testes, lower sperm concentration, and less motile sperm. Except for more often a normal testicular consistency in men with AUDT, no differences were found between men with AUDT and men with CUDT. Also, no differences were found between men with AUDT which had spontaneously descended and men who underwent orchiopexy.
  
  
  CONCLUSIONS
  Fertility potential in men with AUDT is compromised in comparison with healthy controls, but comparable with men with CUDT. This suggests that congenital and acquired UDT share the same etiology. No significant difference was found between men who had spontaneous descent and men needing orchiopexy. However, fertility potential is unknown for men after immediate surgery at diagnosis, and this should be a subject for future studies.
authors.affiliation: Department of Urology, Erasmus University Medical Center, 3000 CA Rotterdam, the Netherlands. Electronic address: j.vanbrakel@erasmusmc.nl.
authors.forename: Jocelyn
authors.initials: J
authors.lastname: van Brakel
authors.affiliation: Department of Urology, Erasmus University Medical Center, 3000 CA Rotterdam, the Netherlands. Electronic address: ries.kranse@gmail.com.
authors.forename: Ries
authors.initials: R
authors.lastname: Kranse
authors.affiliation: Departments of Pediatrics, Endocrinology, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, the Netherlands. Electronic address: s.demuinckkeizer-schrama@erasmusmc.nl.
authors.forename: Sabine M P F
authors.initials: SM
authors.lastname: de Muinck Keizer-Schrama
authors.affiliation: Departments of Pediatrics, Endocrinology, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, the Netherlands. Electronic address: a.e.j.hendriks@erasmusmc.nl.
authors.forename: A Emile J
authors.initials: AE
authors.lastname: Hendriks
authors.affiliation: Departments of Internal Medicine, Endocrinology, Erasmus University Medical Center, 3000 CA Rotterdam, the Netherlands. Electronic address: f.h.dejong@erasmusmc.nl.
authors.forename: Frank H
authors.initials: FH
authors.lastname: de Jong
authors.affiliation: Department of Pediatrics, Medical Center Alkmaar, 1800AM Alkmaar, the Netherlands. Electronic address: w.hack@mca.nl.
authors.forename: Wilfried W M
authors.initials: WW
authors.lastname: Hack
authors.affiliation: Department of Pediatrics, Medical Center Alkmaar, 1800AM Alkmaar, the Netherlands. Electronic address: l.vander.voort@mca.nl.
authors.forename: Laszla M
authors.initials: LM
authors.lastname: van der Voort-Doedens
authors.affiliation: Department of Urology, Erasmus University Medical Center, 3000 CA Rotterdam, the Netherlands. Electronic address: h.j.vanalphen@erasmusmc.nl.
authors.forename: Chris H
authors.initials: CH
authors.lastname: Bangma
authors.affiliation: Department of Pediatric Surgery, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, the Netherlands. Electronic address: f.hazebroek@erasmusmc.nl.
authors.forename: Frans W
authors.initials: FW
authors.lastname: Hazebroek
authors.affiliation: Department of Urology, Erasmus University Medical Center, 3000 CA Rotterdam, the Netherlands. Electronic address: g.r.dohle@erasmusmc.nl.
authors.forename: Gert R
authors.initials: GR
authors.lastname: Dohle
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D003456:Cryptorchidism / Q000209:etiology / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D007248:Infertility, Male / Q000209:etiology*; D053208:Kaplan-Meier Estimate; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D056126:Orchiopexy; D013076:Sperm Count; D013081:Sperm Motility; D055815:Young Adult
keywords: Acquired cryptorchidism; Congenital cryptorchidism; Fertility; Orchiopexy; Undescended testis