title: Normal CYP3A activity during arsenic trioxide therapy.
authors.affiliation: Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
authors.forename: Nelly
authors.initials: N
authors.lastname: Siller
authors.forename: Gerlinde
authors.initials: G
authors.lastname: Egerer
authors.forename: Tilman
authors.initials: T
authors.lastname: Bochtler
authors.forename: Nicolas
authors.initials: N
authors.lastname: Hohmann
authors.forename: Gerd
authors.initials: G
authors.lastname: Mikus
mesh_terms: D000077237:Arsenic Trioxide; D001152:Arsenicals / Q000008:administration & dosage / Q000378:metabolism*; D051544:Cytochrome P-450 CYP3A / Q000097:blood*; D004789:Enzyme Activation / Q000187:drug effects / Q000502:physiology; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000097:blood* / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010087:Oxides / Q000008:administration & dosage / Q000378:metabolism*
chemical_list: D001152:Arsenicals; D010087:Oxides; C104464:CYP3A protein, human; D051544:Cytochrome P-450 CYP3A; D000077237:Arsenic Trioxide