title: Studies on wheat bran Arabinoxylan for its immunostimulatory and protective effects against avian coccidiosis.
abstract: Wheat (Triticum aestivum) bran derived polysaccharides, Arabinoxylans (AXs), were evaluated for their immunostimulatory and protective efficacy against Eimeria infection in chickens. Humoral response revealed significantly higher (P<0.05) total Igs, IgG and IgM titers at days 7th and 14th post primary and secondary injections of sheep red blood cells in the experimental chickens administered with AXs as compared to those of control group. The percent protection and daily weight gains were significantly higher (P<0.05) in the chickens of experimental groups as compared to control; whereas, mean oocyst per gram of droppings and lesion scores were significantly higher (P<0.05) in control group as compared to chickens in the experimental groups. The differences in organ body weight ratio of all the lymphoid organs were statistically non-significant (P>0.05) between experimental and control groups except thymus and cecal tonsils. In conclusion, AXs showed both immunostimulatory and protective effects against coccidiosis in broiler chickens.
authors.affiliation: Immunoparasitology Laboratory, Department of Parasitology, University of Agriculture, Faisalabad 38040, Pakistan.
authors.forename: Masood
authors.initials: M
authors.lastname: Akhtar
authors.affiliation: Immunoparasitology Laboratory, Department of Parasitology, University of Agriculture, Faisalabad 38040, Pakistan.
authors.forename: Ahmad Fraz
authors.initials: AF
authors.lastname: Tariq
authors.affiliation: Immunoparasitology Laboratory, Department of Parasitology, University of Agriculture, Faisalabad 38040, Pakistan.
authors.forename: Mian Muhammad
authors.initials: MM
authors.lastname: Awais
authors.affiliation: Immunoparasitology Laboratory, Department of Parasitology, University of Agriculture, Faisalabad 38040, Pakistan.
authors.forename: Zafar
authors.initials: Z
authors.lastname: Iqbal
authors.affiliation: Department of Physiology and Pharmacology, University of Agriculture, Faisalabad 38040, Pakistan.
authors.forename: Faqir
authors.initials: F
authors.lastname: Muhammad
authors.affiliation: Department of Chemistry and Biochemistry, University of Agriculture, Faisalabad 38040, Pakistan.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Shahid
authors.affiliation: School of Biological Sciences, University of Canterbury, Private Bag 4800, Christchurch, New Zealand.
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Hiszczynska-Sawicka
mesh_terms: D000276:Adjuvants, Immunologic / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use*; D000818:Animals; D002645:Chickens; D003048:Coccidiosis / Q000276:immunology* / Q000517:prevention & control*; D004043:Dietary Fiber / Q000494:pharmacology / Q000627:therapeutic use*; D004539:Eimeria / Q000187:drug effects / Q000276:immunology; D014990:Xylans / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D000276:Adjuvants, Immunologic; D004043:Dietary Fiber; D014990:Xylans; C085118:arabinoxylan