title: Ce(OTf)₃-catalyzed [3 + 2] cycloaddition of azides with nitroolefins: regioselective synthesis of 1,5-disubstituted 1,2,3-triazoles.
abstract: The first example of rare earth metal-catalyzed [3 + 2] cycloaddition of organic azides with nitroolefins and subsequent elimination reaction is described. In the presence of a catalytic amount of Ce(OTf)3, both benzyl and phenyl azides react with a broad range of aryl nitroolefins containing a range of functionalities selectively producing 1,5-disubstituted 1,2,3-triazoles in good to excellent yields.
authors.affiliation: Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), School of Chemistry & Chemical Engineering of Guangxi Normal University , Guilin 541004, People's Republic of China.
authors.forename: Ying-Chun
authors.initials: YC
authors.lastname: Wang
authors.forename: Yu-Yang
authors.initials: YY
authors.lastname: Xie
authors.forename: Hong-En
authors.initials: HE
authors.lastname: Qu
authors.forename: Heng-Shan
authors.initials: HS
authors.lastname: Wang
authors.forename: Ying-Ming
authors.initials: YM
authors.lastname: Pan
authors.forename: Fu-Ping
authors.initials: FP
authors.lastname: Huang
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D001593:Benzyl Compounds / Q000737:chemistry*; D002384:Catalysis; D061565:Cycloaddition Reaction; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure; D009574:Nitro Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D014230:Triazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000475:Alkenes; D001386:Azides; D001593:Benzyl Compounds; D008698:Mesylates; D009574:Nitro Compounds; D014230:Triazoles; C012077:trifluoromethanesulfonic acid