title: Applications of nanomedicine in breast cancer detection, imaging, and therapy.
abstract: Worldwide, breast cancer remains as one of the most common cancer diagnosis and cause of cancer related death among women. Fortunately, nanomedicine has brought forth new potential and hope in breast cancer research. The extremely small size of nanoparticles makes it advantageous and potentially superior to use in tumor detection and imaging. One of the more extensively studied particles is quantum dots, semiconductor crystals which are capable of enhanced labeling and imaging of cancer cells. In addition, due to serious toxicity of chemotherapeutic agents, nano-formulations of breast cancer chemotherapy are under investigation and development. This may provide easier administering route and reduced frequency of drugs. With the use of nanoparticles, drug delivery can be carried out in a minimally invasive fashion and treatment regimens can be made much more targeted and specific for each patient. In this review article, we provide an overview on the role nanomedicine has played in breast cancer and mention some of the latest diagnostic and treatment modalities researched to date.
authors.forename: Yamaan
authors.initials: Y
authors.lastname: Saadeh
authors.forename: Tiffany
authors.initials: T
authors.lastname: Leung
authors.forename: Arpita
authors.initials: A
authors.lastname: Vyas
authors.forename: Lakshmi Shankar
authors.initials: LS
authors.lastname: Chaturvedi
authors.forename: Omathanu
authors.initials: O
authors.lastname: Perumal
authors.forename: Dinesh
authors.initials: D
authors.lastname: Vyas
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D005260:Female; D006801:Humans; D057054:Molecular Imaging / Q000379:methods*; D058990:Molecular Targeted Therapy / Q000379:methods*; D053769:Nanocapsules / Q000008:administration & dosage* / Q000737:chemistry*; D050997:Nanomedicine / Q000379:methods
chemical_list: D000970:Antineoplastic Agents; D053769:Nanocapsules