title: Framework of outcome measures recommended for use in the evaluation of childhood obesity treatment interventions: the CoOR framework.
abstract: BACKGROUND
  Consensus is lacking in determining appropriate outcome measures for assessment of childhood obesity treatments. Inconsistency in the use and reporting of such measures impedes comparisons between treatments and limits consideration of effectiveness. This study aimed to produce a framework of recommended outcome measures: the Childhood obesity treatment evaluation Outcomes Review (CoOR) framework.
  
  
  METHODS
  A systematic review including two searches was conducted to identify (1) existing trial outcome measures and (2) manuscripts describing development/evaluation of outcome measures. Outcomes included anthropometry, diet, eating behaviours, physical activity, sedentary time/behaviour, fitness, physiology, environment, psychological well-being and health-related quality of life. Eligible measures were appraised by the internal team using a system developed from international guidelines, followed by appraisal from national external expert collaborators.
  
  
  RESULTS
  A total of 25,486 papers were identified through both searches. Eligible search 1 trial papers cited 417 additional papers linked to outcome measures, of which 56 were eligible. A further 297 outcome development/evaluation papers met eligibility criteria from search 2. Combined, these described 191 outcome measures. After internal and external appraisal, 52 measures across 10 outcomes were recommended for inclusion in the CoOR framework.
  
  
  CONCLUSIONS
  Application of the CoOR framework will ensure greater consistency in choosing robust outcome measures that are appropriate to population characteristics.
authors.affiliation: Clinical Trials Research Unit, University of Leeds, Leeds, UK.
authors.forename: M
authors.initials: M
authors.lastname: Bryant
authors.forename: L
authors.initials: L
authors.lastname: Ashton
authors.forename: J
authors.initials: J
authors.lastname: Nixon
authors.forename: S
authors.initials: S
authors.lastname: Jebb
authors.forename: J
authors.initials: J
authors.lastname: Wright
authors.forename: K
authors.initials: K
authors.lastname: Roberts
authors.forename: J
authors.initials: J
authors.lastname: Brown
mesh_terms: D000293:Adolescent; D000886:Anthropometry; D001521:Behavior Therapy; D002648:Child; D002675:Child, Preschool; D003362:Cost-Benefit Analysis; D004032:Diet; D004038:Diet, Reducing; D015444:Exercise; D005247:Feeding Behavior; D006801:Humans; D017063:Outcome Assessment, Health Care; D010043:Outcome and Process Assessment, Health Care; D063766:Pediatric Obesity / Q000453:epidemiology / Q000517:prevention & control* / Q000523:psychology; D017410:Practice Guidelines as Topic; D011788:Quality of Life / Q000523:psychology*; D016896:Treatment Outcome
keywords: Framework; outcome measures; quality; systematic review