title: Prevalence of psoriasis among adults in the U.S.: 2003-2006 and 2009-2010 National Health and Nutrition Examination Surveys.
abstract: BACKGROUND
  A 2010 CDC-sponsored consultation of psoriasis, psoriatic arthritis, and public health experts developed a public health agenda for psoriasis and psoriatic arthritis indicating that additional population-based research is needed to better characterize psoriasis in the population.
  
  
  OBJECTIVE
  To better characterize the burden of psoriasis in the U.S. using recent population-based, cross-sectional data in this 2012 analysis.
  
  
  METHODS
  A subset of 10,676 adults aged 20-59 years from the 2003-2006 and 2009-2010 National Health and Nutrition Examination Surveys was used to examine psoriasis prevalence, severity, disparities, health-related quality of life, and selected comorbidities.
  
  
  RESULTS
  The overall prevalence of psoriasis was 3.1% (95% CI=2.6, 3.6); extrapolating to older adults suggests that 6.7 million adults aged ≥20 years are affected. Psoriasis was significantly more prevalent among non-Hispanic whites than other race/ethnicity subgroups, as well as among those with arthritis. Approximately 82% reported no/little or mild disease; the impact of psoriasis on daily life increased with disease severity (p=0.0001 for trend). Those with psoriasis reported significantly more frequent mental distress or mild to severe depression than those without psoriasis. Psoriasis was also significantly associated with obesity and former smoking status.
  
  
  CONCLUSIONS
  Psoriasis is a large public health problem. Further characterizing psoriasis from a public health perspective will require better survey questions and inclusion of these questions in national surveys.
authors.affiliation: CDC, LLC, Atlanta, Georgia. Electronic address: chelmick@cdc.gov.
authors.forename: Charles G
authors.initials: CG
authors.lastname: Helmick
authors.affiliation: SciMetrika, LLC, Durham, North Carolina.
authors.forename: Hyewon
authors.initials: H
authors.lastname: Lee-Han
authors.affiliation: SciMetrika, LLC, Durham, North Carolina.
authors.forename: Shawn C
authors.initials: SC
authors.lastname: Hirsch
authors.affiliation: SciMetrika, LLC, Atlanta, Georgia.
authors.forename: Tiffany L
authors.initials: TL
authors.lastname: Baird
authors.affiliation: SciMetrika, LLC, Durham, North Carolina.
authors.forename: Christopher L
authors.initials: CL
authors.lastname: Bartlett
mesh_terms: D000328:Adult; D015535:Arthritis, Psoriatic / Q000453:epidemiology* / Q000503:physiopathology; D003430:Cross-Sectional Studies; D003863:Depression / Q000453:epidemiology / Q000209:etiology; D005006:Ethnicity / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D009765:Obesity / Q000453:epidemiology; D015995:Prevalence; D011565:Psoriasis / Q000453:epidemiology* / Q000503:physiopathology; D011788:Quality of Life; D012720:Severity of Illness Index; D012907:Smoking / Q000453:epidemiology; D013315:Stress, Psychological / Q000453:epidemiology / Q000209:etiology; D014481:United States / Q000453:epidemiology; D055815:Young Adult
references.citation: Arch Dermatol Res. 2006 Dec;298(7):321-8
references.pmid: 17021763
references.citation: Arch Dermatol. 2001 Mar;137(3):280-4
references.pmid: 11255325
references.citation: J Health Soc Behav. 1997 Mar;38(1):21-37
references.pmid: 9097506
references.citation: BMJ. 1990 Mar 24;300(6727):780-3
references.pmid: 1969757
references.citation: Clin Exp Dermatol. 2009 Mar;34(2):140-4
references.pmid: 19018791
references.citation: Arch Dermatol. 2009 Jun;145(6):700-3
references.pmid: 19528427
references.citation: JAMA. 2006 Oct 11;296(14):1735-41
references.pmid: 17032986
references.citation: J Behav Med. 2012 Apr;35(2):200-10
references.pmid: 21626151
references.citation: J Am Acad Dermatol. 2009 Feb;60(2):218-24
references.pmid: 19022533
references.citation: J Am Acad Dermatol. 2002 Jun;46(6):850-60
references.pmid: 12063481
references.citation: Arch Dermatol. 2005 Dec;141(12):1601-2
references.pmid: 16365269
references.citation: Arch Dermatol. 2007 Dec;143(12):1559-65
references.pmid: 18087008
references.citation: J Am Acad Dermatol. 2005 Jan;52(1):23-6
references.pmid: 15627076
references.citation: Arch Dermatol. 2011 Apr;147(4):419-24
references.pmid: 21173301
references.citation: Arch Dermatol. 2005 Dec;141(12):1580-4
references.pmid: 16365261
references.citation: J Am Acad Dermatol. 2008 Sep;59(3):439-47
references.pmid: 18639364
references.citation: Arch Dermatol. 2009 Apr;145(4):379-82
references.pmid: 19380659
references.citation: NCHS Data Brief. 2011 Jan;(57):1-8
references.pmid: 21592420
references.citation: Gen Hosp Psychiatry. 2007 Mar-Apr;29(2):134-40
references.pmid: 17336662
references.citation: Am J Prev Med. 2013 Apr;44(4):424-426
references.pmid: 23498110
references.citation: J Am Acad Dermatol. 2002 Oct;47(4):512-8
references.pmid: 12271293
references.citation: Arthritis Rheum. 2009 Oct 15;61(10):1373-8
references.pmid: 19790120
references.citation: J Am Acad Dermatol. 2006 Nov;55(5):829-35
references.pmid: 17052489
references.citation: Dermatol Clin. 1996 Jul;14(3):485-96
references.pmid: 8818558
references.citation: Am J Clin Dermatol. 2008;9(2):111-7
references.pmid: 18284265
references.citation: Dermatology. 2006;213(2):102-10
references.pmid: 16902286
references.citation: J Health Psychol. 1997 Oct;2(4):525-37
references.pmid: 22013093
references.citation: J Rheumatol. 2000 May;27(5):1247-50
references.pmid: 10813295
references.citation: J Am Acad Dermatol. 2005 Oct;53(4):573
references.pmid: 16198775
references.citation: Cutis. 2000 Nov;66(5):348-52
references.pmid: 11107520
references.citation: J Dermatolog Treat. 2009;20(1):42-7
references.pmid: 18649164
references.citation: Arch Dermatol. 2005 Dec;141(12):1527-34
references.pmid: 16365253
references.citation: Curr Med Res Opin. 2009 Oct;25(10):2429-38
references.pmid: 19663687
references.citation: J Gen Intern Med. 2001 Sep;16(9):606-13
references.pmid: 11556941
references.citation: J Eur Acad Dermatol Venereol. 2013 Aug;27 Suppl 3:30-5
references.pmid: 23845150
references.citation: Dermatology. 2007;215(1):17-27
references.pmid: 17587835
references.citation: Addict Behav. 2012 Jan;37(1):78-84
references.pmid: 21975024
references.citation: Arch Dermatol. 1999 Dec;135(12):1479-84
references.pmid: 10606053
references.citation: J Investig Dermatol Symp Proc. 2004 Mar;9(2):136-9
references.pmid: 15083780
references.citation: J Am Acad Dermatol. 2008 Nov;59(5):772-80
references.pmid: 19119095
references.citation: Acta Derm Venereol. 2009;89(5):492-7
references.pmid: 19734975
references.citation: J Am Acad Dermatol. 2004 Nov;51(5):704-8
references.pmid: 15523347