title: Dermal skin substitutes for upper limb reconstruction: current status, indications, and contraindications.
abstract: Dermal skin substitutes are a group of biologically engineered materials composed of collagen and glycosaminoglycans and are devoid of cellular structures. These biodegradable materials act as an artificial dermis to promote neovascularization and neodermis formation. Their applications in soft tissue reconstructions are rapidly expanding. In this article, the indications, advantages, and limitations of dermal skin substitutes for reconstruction of soft tissue defects of the upper extremity are reviewed.
authors.affiliation: Section of Plastic Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, MI, USA.
authors.forename: Shady A
authors.initials: SA
authors.lastname: Rehim
authors.affiliation: Department of Surgical Disciplines, All India Institute of Medical Sciences (AIMS), New Delhi, India.
authors.forename: Maneesh
authors.initials: M
authors.lastname: Singhal
authors.affiliation: Section of Plastic Surgery, University of Michigan Medical School, University of Michigan Health System, 2130 Taubman Center, SPC 5340, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5340, USA. Electronic address: kecchung@umich.edu.
authors.forename: Kevin C
authors.initials: KC
authors.lastname: Chung
mesh_terms: D001134:Arm Injuries / Q000601:surgery*; D006801:Humans; D018919:Neovascularization, Physiologic; D019651:Plastic Surgery Procedures / Q000379:methods*; D016038:Skin Transplantation / Q000379:methods; D017768:Skin, Artificial; D017695:Soft Tissue Injuries / Q000601:surgery*; D013524:Surgical Flaps; D015626:Tissue Expansion
keywords: Dermal skin substitutes; Integra; Matriderm; Reconstruction; Trauma; Upper extremity
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