title: Synchronous occurrence of pulmonary adenocarcinoma and pleural diffuse malignant mesothelioma.
abstract: We report a rare case of diffuse malignant pleural mesothelioma synchronous with a localized adenocarcinoma of lung in a 68-year old man with a suspicious history of asbestos exposure. Computed tomography revealed a sub-pleural mass in the lower lobe and an irregular dense area of medium lobe of right lung with thickening of pleura encasing the lung parenchyma and homolateral pleural effusion 1 cm thick. The patient underwent surgery and a right medium and lower lobectomy was performed. Upon frozen sections, intraoperative diagnosis was adenocarcinoma with a poorly differentiated component of lung infiltrating the pleura. The postoperative histological definitive diagnosis with an important contribution of immunostaining was synchronous pulmonary adenocarcinoma and pleural diffuse malignant epithelioid mesothelioma.
authors.forename: H
authors.initials: H
authors.lastname: Imenpour
authors.forename: G P
authors.initials: GP
authors.lastname: Ivaldi
authors.forename: A
authors.initials: A
authors.lastname: Brianti
authors.forename: G
authors.initials: G
authors.lastname: Pastorino
authors.forename: S
authors.initials: S
authors.lastname: Biggi
authors.forename: L
authors.initials: L
authors.lastname: Auriati
authors.forename: C
authors.initials: C
authors.lastname: Simonassi
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D006801:Humans; D008168:Lung / Q000473:pathology*; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008654:Mesothelioma / Q000473:pathology*; D009378:Neoplasms, Multiple Primary; D010994:Pleura / Q000473:pathology*; D010997:Pleural Neoplasms / Q000473:pathology*