title: Patterns and associates of cognitive function, psychosocial wellbeing and health in the Lothian Birth Cohort 1936.
abstract: BACKGROUND
  Cognitive function, psychosocial wellbeing and health are important domains of function. Consistencies and inconsistencies in patterns of wellbeing across these domains may be informative about wellbeing in old age and the ways it is manifested amongst individuals. In this study we investigated whether there were groups of individuals with different profiles of scores across these domains. We also aimed to identify characteristics of any evident groups by comparing them on variables that were not used in identifying the groups.
  
  
  METHODS
  The sample was the Lothian Birth Cohort 1936, which included 1091 participants born in 1936. They are a community-dwelling, narrow-age-range sample of 70-year-olds. Most had taken part in the Scottish Mental Survey 1947 at an average age of 11, making available a measure of childhood intelligence. We used latent class analysis (LCA) to explore possible profiles using 9 variables indicating cognitive functioning, psychosocial wellbeing and health status. Demographic, personality, and lifestyle variables - none of which were used in the LCA - were used to characterize the resulting profile groups.
  
  
  RESULTS
  We accepted a 3-group solution, which we labeled High Wellbeing (65.3%), Low Cognition (20.3%), and Low Bio-Psychosocial (14.5%). Notably, the High Wellbeing group had significantly higher childhood IQ, lower Neuroticism scores, and a lower percentage of current smokers than the other 2 groups.
  
  
  CONCLUSIONS
  The majority of individuals were functioning generally well; however, there was evidence of the presence of groups with different profiles, which may be explained in part in terms of cognitive ability differences. Results suggested that higher life-long intelligence, personality traits associated with less mental distress, and basic health practices such as avoiding smoking are important associates of wellbeing in old age.
authors.forename: Andrea R
authors.initials: AR
authors.lastname: Zammit
authors.forename: John M
authors.initials: JM
authors.lastname: Starr
authors.forename: Wendy
authors.initials: W
authors.lastname: Johnson
authors.affiliation: Centre for Cognitive Aging and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, Scotland, UK. I.Deary@ed.ac.uk.
authors.forename: Ian J
authors.initials: IJ
authors.lastname: Deary
mesh_terms: D000368:Aged; D003071:Cognition / Q000502:physiology*; D015331:Cohort Studies; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008603:Mental Health / Q000639:trends; D012606:Scotland / Q000453:epidemiology; D012944:Social Support
references.citation: J Health Psychol. 2006 Sep;11(5):643-54
references.pmid: 16908463
references.citation: J Gerontol B Psychol Sci Soc Sci. 2006 Jan;61(1):P25-32
references.pmid: 16399938
references.citation: J Clin Epidemiol. 1993 Oct;46(10):1129-40
references.pmid: 8410098
references.citation: Addiction. 2003 Nov;98(11):1575-83
references.pmid: 14616184
references.citation: Annu Rev Psychol. 2010;61:383-409
references.pmid: 19575618
references.citation: Arch Neurol. 2010 Jul;67(7):876-80
references.pmid: 20625097
references.citation: Psychosom Med. 2003 Sep-Oct;65(5):877-83
references.pmid: 14508035
references.citation: Gerontologist. 2001 Aug;41(4):516-24
references.pmid: 11490050
references.citation: Psychol Med. 1998 May;28(3):551-8
references.pmid: 9626712
references.citation: J Gerontol B Psychol Sci Soc Sci. 2004 May;59(3):P110-6
references.pmid: 15118013
references.citation: Nature. 2008 Nov 13;456(7219):175-6
references.pmid: 19005537
references.citation: Neurology. 2009 Jun 9;72(23):2029-35
references.pmid: 19506226
references.citation: Psychol Aging. 2006 Dec;21(4):645-63
references.pmid: 17201487
references.citation: Psychol Med. 2011 Oct;41(10):2057-73
references.pmid: 21349224
references.citation: J Gerontol B Psychol Sci Soc Sci. 2003 Mar;58(2):S74-82
references.pmid: 12646596
references.citation: Annu Rev Clin Psychol. 2010;6:527-50
references.pmid: 20192798
references.citation: J Pers Soc Psychol. 2007 Aug;93(2):266-84
references.pmid: 17645399
references.citation: BMC Psychiatry. 2007 Aug 06;7:37
references.pmid: 17683593
references.citation: J Am Med Dir Assoc. 2009 Feb;10(2):87-92
references.pmid: 19187875
references.citation: Am J Geriatr Psychiatry. 2006 Jan;14(1):43-51
references.pmid: 16407581
references.citation: J Gastroenterol. 2007 Jan;42 Suppl 17:41-7
references.pmid: 17238025
references.citation: Neurobiol Aging. 2009 Apr;30(4):507-14
references.pmid: 19231028
references.citation: J Psychosom Res. 1997 Nov;43(5):529-34
references.pmid: 9394269
references.citation: Psychol Med. 2006 Mar;36(3):345-51
references.pmid: 16393365
references.citation: Arch Gerontol Geriatr. 2005 May-Jun;40(3):241-51
references.pmid: 15814158
references.citation: Dev Psychol. 2013 Dec;49(12):2309-24
references.pmid: 23527494
references.citation: Psychol Aging. 1998 Dec;13(4):676-95
references.pmid: 9883466
references.citation: Psychol Aging. 2007 Dec;22(4):705-18
references.pmid: 18179290
references.citation: J Gerontol. 1972 Oct;27(4):511-23
references.pmid: 5075497
references.citation: BMC Geriatr. 2012 Oct 22;12:64
references.pmid: 23088370
references.citation: Int J Epidemiol. 2012 Dec;41(6):1576-84
references.pmid: 22253310
references.citation: Gerontology. 2012;58(6):545-53
references.pmid: 22907506
references.citation: Psychol Aging. 2001 Dec;16(4):588-99
references.pmid: 11766914
references.citation: Neuroimage. 2004 Aug;22(4):1466-79
references.pmid: 15275904
references.citation: Free Radic Res. 2006 Dec;40(12):1230-8
references.pmid: 17090411
references.citation: Acta Psychiatr Scand. 1983 Jun;67(6):361-70
references.pmid: 6880820
references.citation: Am J Cardiol. 2002 Dec 15;90(12):1279-83
references.pmid: 12480034
references.citation: J Am Geriatr Soc. 2004 Feb;52(2):211-6
references.pmid: 14728629
references.citation: BMC Geriatr. 2007 Dec 05;7:28
references.pmid: 18053258
references.citation: BMJ. 2001 Apr 7;322(7290):819
references.pmid: 11290633
references.citation: J Am Geriatr Soc. 2002 Jul;50(7):1306-8
references.pmid: 12133032
references.citation: Psychol Aging. 2005 Jun;20(2):303-16
references.pmid: 16029094
references.citation: Psychol Methods. 2003 Sep;8(3):338-63
references.pmid: 14596495
references.citation: Am J Geriatr Psychiatry. 2007 Mar;15(3):194-201
references.pmid: 17322132
references.citation: Soc Psychiatry Psychiatr Epidemiol. 2003 Nov;38(11):632-6
references.pmid: 14614551
references.citation: Psychol Bull. 2005 Mar;131(2):260-300
references.pmid: 15740422
references.citation: Ann Neurol. 2002 Aug;52(2):168-74
references.pmid: 12210786
references.citation: J Gerontol B Psychol Sci Soc Sci. 2003 Nov;58(6):P320-8
references.pmid: 14614116
references.citation: J Gerontol B Psychol Sci Soc Sci. 2007 Nov;62(6):P322-30
references.pmid: 18079416
references.citation: Annu Rev Clin Psychol. 2009;5:363-89
references.pmid: 19327033
references.citation: Psychol Aging. 1997 Sep;12(3):433-43
references.pmid: 9308091
references.citation: Arch Gen Psychiatry. 2008 Dec;65(12):1410-8
references.pmid: 19047528
references.citation: Gerontologist. 2002 Dec;42(6):727-33
references.pmid: 12451153
references.citation: J Pers Soc Psychol. 2004 Jan;86(1):174-99
references.pmid: 14717635
references.citation: Addiction. 2004 Apr;99(4):472-81
references.pmid: 15049747
references.citation: J Pers. 1987 Jun;55(2):299-316
references.pmid: 3612472
references.citation: Eur Heart J. 2000 Oct;21(19):1584-90
references.pmid: 10988010
references.citation: Psychol Aging. 1994 Sep;9(3):339-55
references.pmid: 7999320
references.citation: J Consult Clin Psychol. 2002 Feb;70(1):216-27
references.pmid: 11860048
references.citation: Am J Geriatr Psychiatry. 2006 Jan;14(1):6-20
references.pmid: 16407577
references.citation: Psychol Sci Public Interest. 2010 Aug;11(2):53-79
references.pmid: 26168413
references.citation: Arch Neurol. 2004 May;61(5):668-72
references.pmid: 15148142
references.citation: Psychol Aging. 1999 Dec;14(4):605-18
references.pmid: 10632148
references.citation: Gerontologist. 2010 Dec;50(6):821-33
references.pmid: 20513694
references.citation: Neurology. 2006 Oct 10;67(7):1195-200
references.pmid: 17030752
references.citation: Free Radic Biol Med. 2002 Sep 1;33(5):575-86
references.pmid: 12208343
references.citation: Gerontologist. 1997 Aug;37(4):433-40
references.pmid: 9279031
references.citation: Restor Neurol Neurosci. 2009;27(5):391-403
references.pmid: 19847066
references.citation: Int J Aging Hum Dev. 2002;54(1):1-14
references.pmid: 12003497
references.citation: Perspect Psychol Sci. 2007 Dec;2(4):313-45
references.pmid: 26151971
references.citation: Gerontologist. 2012 Dec;52(6):843-56
references.pmid: 22403165
references.citation: Psychol Aging. 1997 Sep;12(3):458-72
references.pmid: 9308093
references.citation: Ann Epidemiol. 2007 Apr;17(4):278-88
references.pmid: 17174570
references.citation: Br J Psychiatry. 2005 Mar;186:190-6
references.pmid: 15738498