title: Recurrence of acute myeloid leukemia in cryptorchid testis: case report.
abstract: A 23-year-old male with a history of bone marrow transplant for acute myeloid leukemia. He presented a large mass in the right inguinal region 5 years ago. Upon physical examination, right-sided cryptorchidism was observed. The tumor markers alpha-fetoprotein and beta-HCG were within normalcy range and lactate dehydrogenase was raised. Computed tomography of the abdomen and pelvis revealed right testicular mass in contiguity with the inguinal canal to the ipsilateral retroperitoneum, associated with right hydronephrosis. Due to the risk of germ-cell tumor in undescended testicle, the patient underwent radical right orchiectomy. The pathological examination showed recurrence of acute myeloid leukemia in the testis. He was referred to oncology for adjuvant therapy. Our literature review found no similar cases described.
authors.affiliation: Hospital do Servidor Público Municipal de São Paulo, São Paulo, SP, Brazil.
authors.forename: Luccas Santos Patto de
authors.initials: LS
authors.lastname: Góes
authors.affiliation: Hospital do Servidor Público Municipal de São Paulo, São Paulo, SP, Brazil.
authors.forename: Roberto Iglesias
authors.initials: RI
authors.lastname: Lopes
authors.affiliation: Hospital do Servidor Público Municipal de São Paulo, São Paulo, SP, Brazil.
authors.forename: Octavio Henrique Arcos
authors.initials: OH
authors.lastname: Campos
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Luiz Carlos Neves de
authors.initials: LC
authors.lastname: Oliveira
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Alexandre Crippa
authors.initials: AC
authors.lastname: Sant'Anna
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Marcos Francisco
authors.initials: MF
authors.lastname: Dall'Oglio
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Miguel
authors.initials: M
authors.lastname: Srougi
mesh_terms: D001706:Biopsy; D016026:Bone Marrow Transplantation; D003456:Cryptorchidism / Q000473:pathology / Q000601:surgery*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000473:pathology / Q000601:surgery*; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery*; D009919:Orchiectomy / Q000379:methods*; D013736:Testicular Neoplasms / Q000473:pathology / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
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