title: [Relationship between cystatin C and coronary artery calcification in patients with intermediate cardiovascular risk].
abstract: OBJECTIVE
  Cardiovascular disease is the leading cause of morbimortality in industrialized countries. Quantification of coronary artery calcium (CAC) has been shown to have an independent and incremental prognostic value over traditional risk factors for the prediction of mortality and cardiovascular events. The aim of our study was to determine the possible relationship between CAC and cystatin C (CTC).
  
  
  METHODS
  We included 104 patients with stable chest pain, free of cardiovascular disease and nephropathy, with intermediate cardiovascular risk. Both CAC (Agatston) and CTC were determined.
  
  
  RESULTS
  CTC was independently associated with the CAC level and the presence of coronary disease.
  
  
  CONCLUSIONS
  CTC values may be associated with CAC and coronary disease. Further studies are needed to know the importance of these markers in clinical practice.
authors.affiliation: UGC del Corazón, Instituto de Biomedicina de Málaga (IBIMA), Hospital Clínico Universitario Virgen de la Victoria, Málaga, España. Electronic address: amalio_ruiz@hotmail.com.
authors.forename: Amalio
authors.initials: A
authors.lastname: Ruiz-Salas
authors.affiliation: Servicio de Hematología, Hospital Clínico Universitario Virgen de la Victoria, Málaga, España.
authors.forename: Miriam
authors.initials: M
authors.lastname: Cortés-Rodríguez
authors.affiliation: Servicio de Radiología, Hospital Clínico Universitario Virgen de la Victoria, Málaga, España.
authors.forename: Nieves
authors.initials: N
authors.lastname: Alegre-Bayo
authors.affiliation: Servicio de Radiología, Hospital Clínico Universitario Virgen de la Victoria, Málaga, España.
authors.forename: José
authors.initials: J
authors.lastname: Algarra-García
authors.affiliation: UGC del Corazón, Instituto de Biomedicina de Málaga (IBIMA), Hospital Clínico Universitario Virgen de la Victoria, Málaga, España.
authors.forename: Eduardo
authors.initials: E
authors.lastname: de Teresa Galván
authors.affiliation: UGC del Corazón, Instituto de Biomedicina de Málaga (IBIMA), Hospital Clínico Universitario Virgen de la Victoria, Málaga, España.
authors.forename: Manuel F
authors.initials: MF
authors.lastname: Jiménez-Navarro
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D003324:Coronary Artery Disease / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D055316:Cystatin C / Q000097:blood*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D061205:Vascular Calcification / Q000097:blood / Q000150:complications / Q000175:diagnosis*
chemical_list: D015415:Biomarkers; D055316:Cystatin C
keywords: Arterias coronarias; Aterosclerosis; Atherosclerosis; Cistatina C; Coronary arteries; Cystatin C