title: [Antireflux surgery more cost-effective than medication after all?].
abstract: Although fundoplication has been found effective in the treatment of reflux disease, its long-term results have raised doubts due to the large number of patients taking acid blocker medication after the operation. Based on the five-year follow-up of the REFLUX study, reflux symptoms and quality of life associated with reflux were improved after the operation. Laparoscopic fundoplication was found to be a cost-effective form of treatment among those having a chronic reflux disease. The operation can be recommended for treating reflux disease in patients exhibiting a non-optimal PPI drug response.
authors.forename: Tuomo
authors.initials: T
authors.lastname: Rantanen
mesh_terms: D002908:Chronic Disease; D003362:Cost-Benefit Analysis; D018662:Fundoplication / Q000191:economics* / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy; D054328:Proton Pump Inhibitors / Q000627:therapeutic use; D011788:Quality of Life
chemical_list: D054328:Proton Pump Inhibitors