title: [Quantitative determination of penicillins by iodometry using potassium hydrogen peroxymonosulfate].
abstract: The kinetics and stoichiometry of S-oxidation of semisynthetic penicillins (amoxicillin trihydrate, ampicillin trihydrate, sodium salt of oxacillin and ticarcillin disodium salt) by potassium hydrogen peroxymonosulfate in aqueous solutions at pH 3-6 was studied by iodometric titration: 1 mol of KNSO5 per 1 mol of penicillin, the quantitative interaction is achieved in 1 min (time of observation). A unified method was developed and the possibility of quantification of penicillins by the iodometric method using potassium hydrogen peroxymonosulfate as an analytical reagent was shown.
authors.forename: N E
authors.initials: NE
authors.lastname: Blazhevskiĭ
authors.forename: S P
authors.initials: SP
authors.lastname: Karpova
authors.forename: V I
authors.initials: VI
authors.lastname: Kabachyĭ
mesh_terms: D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D010084:Oxidation-Reduction; D010406:Penicillins / Q000032:analysis*; D012680:Sensitivity and Specificity; D013464:Sulfuric Acids / Q000737:chemistry*
chemical_list: D010406:Penicillins; D013464:Sulfuric Acids; C048813:potassium peroxymonosulfuric acid