title: Concurrent degradation of tetrabromobisphenol A by Ochrobactrum sp. T under aerobic condition and estrogenic transition during these processes.
abstract: The effect of concurrent degradation of tetrabromobisphenol A (TBBPA) by the strain Ochrobactrum sp. T under aerobic condition was investigated. The results demonstrated that four extra energy source-addition systems still followed pseudo-first order kinetics. The addition of ethanol or glucose could promote the biodegradation ability of Ochrobactrum sp. T to TBBPA, and 90.1 percent and 77.5 percent of TBBPA (5mg L(-1)) could be removed with corresponding TBBPA half-lives of 26 and 36h, respectively, after 96h reaction. Comparatively, the degradation efficiency of the sole TBBPA system was only 72.9 percent under the same condition. In contrast, two other co-substrates 2,4,6-tribromophenol (TBP) and bisphenol A (BPA) showed a negative effect on the TBBPA biodegradation, and the degradation efficiencies of TBBPA were achieved as 44.7 percent and 67.4 percent, respectively. For the TBBPA+TBP system, the competitive inhibition for the TBBPA debromination was less than the inhibition of the toxicity to the bacterium. While for the TBBPA+BPA system, the degradation of TBBPA could be promoted at the beginning of the reaction, and was then inhibited slightly with further prolonging of reaction time. This is probably due to the substrates being oxidized, and BPA can consume partial oxygen and provide the electrons during the concurrent biodegradation process. In addition, although higher estrogenic activity could be detected for the debrominated intermediates in TBBPA co-degradation process than the original TBBPA, the estrogenicity of the whole system still decreased finally after 96h degradation.
authors.affiliation: State Key Laboratory of Organic Geochemistry and Guangdong Key Laboratory of Environmental Resources Utilization and Protection, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China; College of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji 721013, China; University of Chinese Academy of Sciences, Beijing 100049, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Zu
authors.affiliation: State Key Laboratory of Organic Geochemistry and Guangdong Key Laboratory of Environmental Resources Utilization and Protection, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China; University of Chinese Academy of Sciences, Beijing 100049, China.
authors.forename: Jukun
authors.initials: J
authors.lastname: Xiong
authors.affiliation: State Key Laboratory of Organic Geochemistry and Guangdong Key Laboratory of Environmental Resources Utilization and Protection, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China. Electronic address: ligy1999@gig.ac.cn.
authors.forename: Guiying
authors.initials: G
authors.lastname: Li
authors.affiliation: Institute of Hygiene and Environmental Medicine, Academy of Military Medical Science, Tianjin 300050, China.
authors.forename: Yanjun
authors.initials: Y
authors.lastname: Fang
authors.affiliation: State Key Laboratory of Organic Geochemistry and Guangdong Key Laboratory of Environmental Resources Utilization and Protection, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China; Key Laboratory of Reproduction and Genetics of Guangdong Higher Education Institutes, Guangzhou Medical University and The Third Affiliated Hospital, Guangzhou 510150, China. Electronic address: antc99@gig.ac.cn.
authors.forename: Taicheng
authors.initials: T
authors.lastname: An
mesh_terms: D000332:Aerobiosis; D001559:Benzhydryl Compounds / Q000737:chemistry; D001673:Biodegradation, Environmental; D004785:Environmental Pollutants / Q000378:metabolism; D004967:Estrogens / Q000737:chemistry; D042041:Ochrobactrum / Q000378:metabolism*; D010636:Phenols / Q000737:chemistry; D011075:Polybrominated Biphenyls / Q000378:metabolism*; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D004785:Environmental Pollutants; D004967:Estrogens; D010636:Phenols; D011075:Polybrominated Biphenyls; C020806:tetrabromobisphenol A; C006780:bisphenol A; D000098826:Bisphenol A Compounds; C004554:2,4,6-tribromophenol
keywords: Aerobic degradation; Concurrent biodegradation; Estrogenic activity; Kinetics; Ochrobactrum sp. T; Tetrabromobisphenol A