title: [Nosocomial infections after cardiac surgery in infants and children with congenital heart disease].
abstract: BACKGROUND
  Nosocomial infections generate high morbidity and mortality in children undergoing cardiac surgery.
  
  
  OBJECTIVE
  To determine risk factors for nosocomial infections in children after congenital heart surgery.
  
  
  METHODS
  A retrospective case-control study, in patients younger than 15 years undergoing surgery for congenital heart disease from January 2007 to December 2011 admitted to the Pediatric Critical Patient Unit (UPC-P) in a university hospital. For cases, the information was analyzed from the first episode of infection.
  
  
  RESULTS
  39 patients who develop infections and 39 controls who did not develop infection were enrolled. The median age of cases was 2 months. We identified a number of factors associated with the occurrence of infections, highlighting in univariate analysis: age, weight, univentricular heart physiology, complexity of the surgical procedure according to RACHS-1 and cardiopulmonary bypass (CPB) time ≥ 200 minutes. Multivariate analysis identified CPB time ≥ 200 minutes as the major risk factor, with an OR of 11.57 (CI: 1.04 to 128.5).
  
  
  CONCLUSIONS
  CPB time ≥ 200 minutes was the mayor risk factor associated with the development of nosocomial infections.
authors.forename: José
authors.initials: J
authors.lastname: Barriga
authors.forename: Jaime
authors.initials: J
authors.lastname: Cerda
authors.forename: Katia
authors.initials: K
authors.lastname: Abarca
authors.forename: Marcela
authors.initials: M
authors.lastname: Ferrés
authors.forename: Paula
authors.initials: P
authors.lastname: Fajuri
authors.forename: María
authors.initials: M
authors.lastname: Riquelme
authors.forename: Diego
authors.initials: D
authors.lastname: Carrillo
authors.forename: Cristián
authors.initials: C
authors.lastname: Clavería
mesh_terms: D002648:Child; D002677:Chile / Q000453:epidemiology; D003428:Cross Infection / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006330:Heart Defects, Congenital / Q000601:surgery*; D006801:Humans; D007223:Infant; D015278:Intensive Care Units, Pediatric / Q000706:statistics & numerical data*; D008297:Male; D015999:Multivariate Analysis; D011183:Postoperative Complications / Q000453:epidemiology* / Q000382:microbiology; D012307:Risk Factors