title: A tetranaphthoimidazolium receptor as a fluorescent chemosensor for phytate.
abstract: A new tetranaphthoimidazolium receptor was synthesized and reported to be a selective fluorescent chemosensor for phytate, myo-inositol hexakisphosphate (IP6). In a 100% aqueous solution at pH 7.4, chemosensor 1 showed a selective fluorescence enhancement for IP6 over IP3, phosphates, pyrophosphates, AMP, ADP and ATP. An excimer emission at 465 nm linearly increases in the range of 300 nM to 1 μM with a detection limit of 2.28 × 10(-7) M. In addition, first live cell imaging of IP6 has been demonstrated by using a synthetic receptor.
authors.affiliation: Department of Chemistry and Nano Science, Global Top5 Research Program, Ewha Womans University, Seoul 120-750, Korea. jyoon@ewha.ac.kr.
authors.forename: Minji
authors.initials: M
authors.lastname: Lee
authors.forename: Jong Hun
authors.initials: JH
authors.lastname: Moon
authors.forename: Eun Jin
authors.initials: EJ
authors.lastname: Jun
authors.forename: Gyoungmi
authors.initials: G
authors.lastname: Kim
authors.forename: Yong-Uk
authors.initials: YU
authors.lastname: Kwon
authors.forename: Jin Yong
authors.initials: JY
authors.lastname: Lee
authors.forename: Juyoung
authors.initials: J
authors.lastname: Yoon
mesh_terms: D066241:Carbon-13 Magnetic Resonance Spectroscopy; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D007093:Imidazoles / Q000737:chemistry*; D010833:Phytic Acid / Q000032:analysis*; D066244:Proton Magnetic Resonance Spectroscopy; D013050:Spectrometry, Fluorescence; D016339:Spectrometry, Mass, Fast Atom Bombardment
chemical_list: D005456:Fluorescent Dyes; D007093:Imidazoles; D010833:Phytic Acid