title: Left main coronary artery compression syndrome and spontaneous coronary artery dissection: coincidence or pathologic association?
abstract: Left main coronary artery compression syndrome (LMCS) in patients with severe pulmonary arterial hypertension (PAH) is an unusual, and often a missed cause of exertional angina. Spontaneous coronary dissection (SCD) is a rare cause of acute coronary syndrome of unknown etiology, with predilection to women in the 20s-40s. Weather the co-presence of LMCS and SCD in certain patients is a coincidence or of pathological significance is not known. The optimal management strategy of each of these conditions remains controversial. We report a case of SCD in a patient with PAH and LMCS, successfully treated with conservative medical therapy.
authors.affiliation: Cardiology Division, Temple University School of Medicine, 3041 N. Broad Street, Suite 945, Parkinson Pavilion, Philadelphia, PA 19140, USA. Electronic address: adnanalkhouli@gmail.com.
authors.forename: Mohamad
authors.initials: M
authors.lastname: Alkhouli
authors.affiliation: Cardiology Division, Temple University School of Medicine, 3041 N. Broad Street, Suite 945, Parkinson Pavilion, Philadelphia, PA 19140, USA.
authors.forename: Nazmul
authors.initials: N
authors.lastname: Huda
authors.affiliation: Cardiology Division, Temple University School of Medicine, 3041 N. Broad Street, Suite 945, Parkinson Pavilion, Philadelphia, PA 19140, USA.
authors.forename: Riyaz
authors.initials: R
authors.lastname: Bashir
authors.affiliation: Cardiology Division, Temple University School of Medicine, 3041 N. Broad Street, Suite 945, Parkinson Pavilion, Philadelphia, PA 19140, USA.
authors.forename: Pravin
authors.initials: P
authors.lastname: Patil
authors.affiliation: Cardiology Division, Temple University School of Medicine, 3041 N. Broad Street, Suite 945, Parkinson Pavilion, Philadelphia, PA 19140, USA.
authors.forename: Brian
authors.initials: B
authors.lastname: O'Murchu
mesh_terms: D054058:Acute Coronary Syndrome / Q000209:etiology*; D000328:Adult; D000784:Aortic Dissection / Q000150:complications*; D002637:Chest Pain / Q000209:etiology; D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D065627:Familial Primary Pulmonary Hypertension; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications* / Q000188:drug therapy; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011651:Pulmonary Artery / Q000473:pathology
chemical_list: D010975:Platelet Aggregation Inhibitors
keywords: Cardiac computed tomography; Intravascular ultrasound; Left main compression; Pulmonary artery dilatation; Pulmonary hypertension; Spontaneous coronary dissection