title: Distribution of polycyclic aromatic hydrocarbon (PAH) residues in several tissues of edible fishes from the largest freshwater lake in China, Poyang Lake, and associated human health risk assessment.
abstract: The residual levels, tissue distribution and human health risk assessment of polycyclic aromatic hydrocarbons (PAHs) in edible fishes, bighead carp (Aristichthys nobilis) and silver carp (Hypophthalmichthys molitrix), from the largest freshwater lake in China, Poyang Lake, were studied. PAH concentrations ranged from 105 to 513ng g(-1)ww and from 53.9 to 401ng g(-1)ww in different tissues of bighead carp and silver carp, respectively. Low molecular weight (LMW) PAHs were the predominant compounds, suggesting the gill-water transfer might be the major exposure route for PAHs in the studied fish species. Tissue distribution indicated that the hepatobiliary system accumulated higher concentrations of PAHs than the extrahepatic tissues with bile being the most predominant tissue for both species. Composition analysis demonstrated that PAHs were from the combined petrogenic and pyrogenic origin, and the gasoline combustion might be the main source. A preliminary evaluation of human health risk using benzo[a]pyrene (BaP) potency equivalent concentration (PEC) as well as the incremental lifetime cancer risk (ILCR) indicated that PAHs in fish would induce potential carcinogenic effects.
authors.affiliation: State Key Laboratory of Lake Science and Environment Research, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing 210008, China.
authors.forename: Zhonghua
authors.initials: Z
authors.lastname: Zhao
authors.affiliation: State Key Laboratory of Lake Science and Environment Research, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing 210008, China. Electronic address: luzhang@niglas.ac.cn.
authors.forename: Lu
authors.initials: L
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Lake Science and Environment Research, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing 210008, China.
authors.forename: Yongjiu
authors.initials: Y
authors.lastname: Cai
authors.affiliation: State Key Laboratory of Lake Science and Environment Research, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing 210008, China.
authors.forename: Yuwei
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000818:Animals; D001646:Bile / Q000737:chemistry; D002347:Carps; D002681:China; D004784:Environmental Monitoring; D005506:Food Contamination; D005880:Gills / Q000737:chemistry; D006801:Humans; D060106:Lakes / Q000737:chemistry*; D008099:Liver / Q000737:chemistry; D018482:Muscle, Skeletal / Q000737:chemistry; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis* / Q000737:chemistry; D018570:Risk Assessment; D012867:Skin / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D011084:Polycyclic Aromatic Hydrocarbons; D014874:Water Pollutants, Chemical
keywords: Bioaccumulation; Edible fishes; Human health risk assessment; Polycyclic aromatic hydrocarbons (PAHs); Poyang Lake