title: Application of indocyanine green-fluorescence imaging to full-thickness cholecystectomy.
abstract: Fluorescence imaging using indocyanine green (ICG) has recently been applied to laparoscopic surgery to identify cancerous tissues, lymph nodes, and vascular anatomy. Here we report the application of ICG-fluorescence imaging to visualize the boundary between the liver and subserosal tissues of the gallbladder during laparoscopic full-thickness cholecystectomy. A patient with a potentially malignant gallbladder lesion was administered 2.5-mg intravenous ICG just before laparoscopic full-thickness cholecystectomy. Intraoperative fluorescence imaging enabled the real-time delineation of both extrahepatic bile duct anatomy and hepatic parenchyma throughout the procedure, which resulted in complete removal of subserosal tissues between liver and gallbladder. Safe and feasible ICG-fluorescence imaging can be widely applied to laparoscopic hepatobiliary surgery by utilizing a biliary excretion property of ICG.
authors.affiliation: Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan.
authors.forename: Kiyomi
authors.initials: K
authors.lastname: Morita
authors.forename: Takeaki
authors.initials: T
authors.lastname: Ishizawa
authors.forename: Keigo
authors.initials: K
authors.lastname: Tani
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Harada
authors.forename: Atsushi
authors.initials: A
authors.lastname: Shimizu
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Takemura
authors.forename: Junichi
authors.initials: J
authors.lastname: Kaneko
authors.forename: Taku
authors.initials: T
authors.lastname: Aoki
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Sakamoto
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Sugawara
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Hasegawa
authors.forename: Norihiro
authors.initials: N
authors.lastname: Kokudo
mesh_terms: D017081:Cholecystectomy, Laparoscopic / Q000379:methods*; D002764:Cholecystitis / Q000601:surgery*; D004396:Coloring Agents; D005260:Female; D005453:Fluorescence; D006801:Humans; D007208:Indocyanine Green; D008875:Middle Aged
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green
keywords: Fluorescence imaging; indocyanine green; laparoscopic cholecystectomy