title: [Advances in bone dysplasias].
abstract: The prevalence of bone dysplasias is estimated to be one case per 1,000 inhabitants, which suggests that, at some point in the career of an orthopaedic surgeon, he will face with one of these patients. The aim of this paper is to review the general aspects of bone dysplasias and focus on those, which due to their frequency and importance, we consider most relevant (achondroplasia, multiple epiphyseal dysplasia, spondyloepiphyseal dysplasia, osteogenesis imperfecta), reviewing their fundamental features and the latest therapeutic advances. There is no cure for these diseases, so early diagnosis and appropriate therapeutic management, becomes the key to improving quality of life of these patients.
authors.affiliation: Servicio de Traumatología Infantil, Hospitales Universitarios Virgen del Rocío, Sevilla, España. Electronic address: Estrellabp86@hotmail.com.
authors.forename: E
authors.initials: E
authors.lastname: Borrego
authors.affiliation: Servicio de Traumatología Infantil, Hospitales Universitarios Virgen del Rocío, Sevilla, España.
authors.forename: D M
authors.initials: DM
authors.lastname: Farrington
authors.affiliation: Servicio de Traumatología Infantil, Hospitales Universitarios Virgen del Rocío, Sevilla, España.
authors.forename: F J
authors.initials: FJ
authors.lastname: Downey
mesh_terms: D000130:Achondroplasia / Q000175:diagnosis / Q000628:therapy; D001848:Bone Diseases, Developmental / Q000175:diagnosis / Q000628:therapy; D002648:Child; D006801:Humans; D010009:Osteochondrodysplasias / Q000175:diagnosis / Q000628:therapy; D010013:Osteogenesis Imperfecta / Q000175:diagnosis / Q000628:therapy
keywords: Achondroplasia; Acondroplasia; Bone dysplasias; Displasia epifisaria múltiple; Displasia espondiloepifisaria; Displasias óseas; Multiple epiphyseal dysplasia; Osteogenesis imperfecta; Osteogénesis imperfecta; Spondyloepiphyseal dysplasia