title: Acute inhalation exposure to titanium ethanolate as a possible cause of metal fume fever.
abstract: Occupational inhalation exposure to noxious agents is not uncommon. Herein, we present a 26-year-old male student who had accidental acute inhalation exposure to a large quantity of titanium ethanolate and hydrogen chloride in chemistry lab. He was referred to the emergency department of our hospital with low-grade fever, dyspnea, headache, fatigue and myalgia. After 24 hrs of symptomatic treatment (oxygen therapy and acetaminophen), the fever was subsided and the patient discharged home in a good clinical condition. The presented symptoms could be interpreted as a form of metal fume fever. It can therefore be concluded that organo-metallic compound of titanium metal may have the potential to produce metal fume fever in human.
authors.forename: M
authors.initials: M
authors.lastname: Ahmadimanesh
authors.forename: S
authors.initials: S
authors.lastname: Shadnia
authors.affiliation: Pharmacology Department, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. ghazikha@sina.tums.ac.ir.
authors.forename: M
authors.initials: M
authors.lastname: Ghazi-Khansari
mesh_terms: D000082:Acetaminophen / Q000008:administration & dosage / Q000627:therapeutic use*; D000328:Adult; D000336:Aerosols; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000627:therapeutic use; D045424:Complex Mixtures / Q000009:adverse effects; D004417:Dyspnea / Q000139:chemically induced* / Q000628:therapy; D000431:Ethanol; D005334:Fever / Q000139:chemically induced* / Q000628:therapy; D006801:Humans; D006851:Hydrochloric Acid; D019570:Inhalation Exposure / Q000009:adverse effects*; D007492:Iran; D007753:Laboratories; D008297:Male; D010102:Oxygen Inhalation Therapy; D013334:Students; D014025:Titanium / Q000506:poisoning*
chemical_list: D000336:Aerosols; D018712:Analgesics, Non-Narcotic; D045424:Complex Mixtures; D000082:Acetaminophen; D000431:Ethanol; D014025:Titanium; D006851:Hydrochloric Acid
references.citation: Am J Emerg Med. 2008 Jun;26(5):608-11
references.pmid: 18534293
references.citation: J La State Med Soc. 2009 Nov-Dec;161(6):348-51
references.pmid: 20108830