title: Enantio- and diastereoselective synthesis of spiro-epoxyoxindoles.
abstract: An asymmetric synthesis of epoxyoxindoles from isatins has been developed by employing chiral sulfur ylides generated in situ from camphor-derived sulfonium salts. This reaction allows an efficient access to enantioenriched spiro-epoxyoxindoles under mild reaction conditions, featuring high yields and excellent enantio- and diastereoselectivities.
authors.affiliation: Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University , 152 Luoyu Road, Wuhan, Hubei 430079, China.
authors.forename: Amina
authors.initials: A
authors.lastname: Boucherif
authors.forename: Qing-Qing
authors.initials: QQ
authors.lastname: Yang
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wang
authors.forename: Jia-Rong
authors.initials: JR
authors.lastname: Chen
authors.forename: Liang-Qiu
authors.initials: LQ
authors.lastname: Lu
authors.forename: Wen-Jing
authors.initials: WJ
authors.lastname: Xiao
mesh_terms: D004852:Epoxy Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D004852:Epoxy Compounds; D007211:Indoles; D013141:Spiro Compounds