title: Physical activity in overweight and obese adolescents: systematic review of the effects on physical fitness components and cardiovascular risk factors.
abstract: BACKGROUND
  The increasing prevalence of obesity in the pediatric age range has become a major concern. Studies have investigated the role of physical activity (PA) to prevent obesity in this population. However, previous reviews did not focus on the effects of PA in overweight/obese adolescents on physical fitness and risk factors for cardiovascular disease altogether.
  
  
  OBJECTIVE
  The present systematic review analyzed trials investigating the effect of PA on aerobic capacity, muscle strength, body composition, hemodynamic variables, biochemical markers, and endothelial function in obese/overweight adolescents.
  
  
  METHODS
  PubMed, LILACS, Web of Science, Scopus (including Embase), and SPORTDiscus databases were searched for relevant reports without time limits. Inclusion criteria included studies published in English, with overweight and obese adolescents aged 12-17 years. The review was registered (Number CRD42013004632) on PROSPERO, the International Prospective Register of Systematic Reviews.
  
  
  RESULTS
  The results indicated that PA is associated with significant and beneficial changes in fat percentage, waist circumference, systolic blood pressure, insulin, low-density lipoprotein cholesterol, and total cholesterol, as well as with small non-significant changes in diastolic blood pressure, glucose, and high-density lipoprotein cholesterol.
  
  
  CONCLUSIONS
  Although limited, results from controlled trials suggest that PA intervention may improve physical fitness and risk factors for cardiovascular disease in adolescents who are overweight or obese.
authors.affiliation: Institute of Physical Education and Sports, Laboratory of Physical Activity and Health Promotion, State University of Rio de Janeiro, Rua São Francisco Xavier 524/sala 8121F-Maracanã, Rio de Janeiro, RJ, CEP 20550-013, Brazil.
authors.forename: Fabrício
authors.initials: F
authors.lastname: Vasconcellos
authors.forename: André
authors.initials: A
authors.lastname: Seabra
authors.forename: Peter T
authors.initials: PT
authors.lastname: Katzmarzyk
authors.forename: Luiz Guilherme
authors.initials: LG
authors.lastname: Kraemer-Aguiar
authors.forename: Eliete
authors.initials: E
authors.lastname: Bouskela
authors.forename: Paulo
authors.initials: P
authors.lastname: Farinatti
mesh_terms: D000293:Adolescent; D015415:Biomarkers / Q000097:blood; D001823:Body Composition; D002318:Cardiovascular Diseases / Q000503:physiopathology* / Q000517:prevention & control; D004727:Endothelium / Q000502:physiology; D015444:Exercise / Q000502:physiology*; D006439:Hemodynamics; D006801:Humans; D007249:Inflammation / Q000503:physiopathology; D009765:Obesity / Q000503:physiopathology*; D050177:Overweight / Q000503:physiopathology*; D010809:Physical Fitness; D012307:Risk Factors
chemical_list: D015415:Biomarkers
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