title: [Comparison of epidural and opioid analgesia effects on frequency of paralytic ileus development in patients of surgical intensive care unit].
abstract: The impact of epidural analgesia (EA) on bowel peristalsis in Surgical Intensive Care Unit (SICU) patients is not well known. This study was designed to determine if EA improves bowel motility and decreases the incidence of postoperative paralytic ileus compared to patients receiving systemic opioid analgesia (OA). Through prospective cohort study we investigated 386 SICU patients who received EA [n = 70 (18.13%)], or OA +/- ketorolac trometamol [n = 316 (81.87%)]. We showed that EA does not improve time to defecation and does not decrease the incidence of paralytic ileus in SICU patients.
authors.forename: R V
authors.initials: RV
authors.lastname: Akopian
mesh_terms: D000005:Abdomen / Q000601:surgery; D015360:Analgesia, Epidural / Q000379:methods*; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000627:therapeutic use*; D003672:Defecation / Q000187:drug effects; D005260:Female; D005769:Gastrointestinal Motility / Q000187:drug effects; D006801:Humans; D007362:Intensive Care Units; D007418:Intestinal Pseudo-Obstruction / Q000453:epidemiology* / Q000209:etiology; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000517:prevention & control*; D011446:Prospective Studies; D013997:Time Factors
chemical_list: D000701:Analgesics, Opioid