title: Intelligent and ultrasensitive analysis of mercury trace contaminants via plasmonic metamaterial-based surface-enhanced Raman spectroscopy.
abstract: Label-free molecular logic gates (AND, INHIBIT, and OR) are constructed based on specific conformation modulation of a guanine- and thymine-rich DNA, while the optical readout is enabled by the tunable metamaterials which serve as a substrate for surface enhanced Raman spectroscopy. The DNA logic is simple to operate, highly reproducible, and can be stimulated by ultra-low concentration of the external inputs, enabling an extremely sensitive detection of mercury ions down to 2 × 10(-4) ppb.
authors.affiliation: Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, 637371.
authors.forename: Cuong
authors.initials: C
authors.lastname: Cao
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.forename: Shuzhou
authors.initials: S
authors.lastname: Li
authors.forename: Qihua
authors.initials: Q
authors.lastname: Xiong
mesh_terms: D057230:Limit of Detection; D008628:Mercury / Q000032:analysis*; D013059:Spectrum Analysis, Raman / Q000379:methods*
chemical_list: D008628:Mercury
keywords: SERS; label-free detection; mercury ions; metamaterials; molecular logic gate