title: Staphylococcus aureus mobile genetic elements.
abstract: Among the bacteria groups, most of them are known to be beneficial to human being whereas only a minority is being recognized as harmful. The pathogenicity of bacteria is due, in part, to their rapid adaptation in the presence of selective pressures exerted by the human host. In addition, through their genomes, bacteria are subject to mutations, various rearrangements or horizontal gene transfer among and/or within bacterial species. Bacteria's essential metabolic functions are generally encoding by the core genes. Apart of the core genes, there are several number of mobile genetic elements (MGE) acquired by horizontal gene transfer that might be beneficial under certain environmental conditions. These MGE namely bacteriophages, transposons, plasmids, and pathogenicity islands represent about 15% Staphylococcus aureus genomes. The acquisition of most of the MGE is made by horizontal genomic islands (GEI), recognized as discrete DNA segments between closely related strains, transfer. The GEI contributes to the wide spread of microorganisms with an important effect on their genome plasticity and evolution. The GEI are also involve in the antibiotics resistance and virulence genes dissemination. In this review, we summarize the mobile genetic elements of S. aureus.
authors.affiliation: Department of Biochemistry and Microbiology, Faculty of Food and Biochemical Technology, Institute of Chemical Technology, Prague, Czech Republic.
authors.forename: Babek
authors.initials: B
authors.lastname: Alibayov
authors.forename: Lamine
authors.initials: L
authors.lastname: Baba-Moussa
authors.forename: Haziz
authors.initials: H
authors.lastname: Sina
authors.forename: Kamila
authors.initials: K
authors.lastname: Zdeňková
authors.forename: Kateřina
authors.initials: K
authors.lastname: Demnerová
mesh_terms: D001435:Bacteriophages / Q000235:genetics*; D002876:Chromosomes, Bacterial / Q000235:genetics*; D004251:DNA Transposable Elements / Q000235:genetics*; D022761:Gene Transfer, Horizontal / Q000235:genetics*; D044404:Genomic Islands / Q000235:genetics*; D006801:Humans; D020071:Interspersed Repetitive Sequences / Q000235:genetics*; D013211:Staphylococcus aureus / Q000235:genetics*
chemical_list: D004251:DNA Transposable Elements
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