title: Correlation between PFGE Groups and mrp/epf/sly Genotypes of Human Streptococcus suis Serotype 2 in Northern Thailand.
abstract: Streptococcus suis infection is a severe zoonotic disease commonly found in Northern Thailand where people often consume raw pork and/or pig's blood. The most frequent clinical presentations are meningitis, sepsis, and endocarditis with higher rate of mortality and hearing loss sequelae. To clarify the correlation between pulsed-field gel electrophoresis (PFGE) groups and mrp/epf/sly genotypes of S. suis serotype 2, 62 patient and 4 healthy pig isolates from Northern Thailand were studied. By PFGE analysis, at 66% homology, most human isolates (69.4%) and 1 pig isolate were in group A, whereas 14.5% of human isolates and 3 out of 4 pig isolates were in group D. According to mrp/epf/sly genotypes, 80.6% of human isolates were identified in mrp (+) epf (-) sly (-) and only 12.9% were in mrp (-) epf (-) sly (+) genotypes; in contrast, 1 and 3 pig isolates were detected in these two genotypes, respectively. Interestingly, all isolates of S. suis serotype 2 classified in PFGE groups A, B, and E were set in mrp (+) epf (-) sly (-) genotypes. These data show a close correlation between PFGE groups and mrp/epf/sly genotypes of human S. suis serotype 2.
authors.affiliation: Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
authors.forename: Prasit
authors.initials: P
authors.lastname: Tharavichitkul
authors.affiliation: Department of Veterinary Biosciences and Public Health, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
authors.forename: Kanreuthai
authors.initials: K
authors.lastname: Wongsawan
authors.affiliation: Department of Animal Hygiene, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Aomori 034-8628, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Takenami
authors.affiliation: Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
authors.forename: Sumalee
authors.initials: S
authors.lastname: Pruksakorn
authors.affiliation: Department of Medicine, Lamphun Provincial Hospital, Lamphun 51000, Thailand.
authors.forename: Achara
authors.initials: A
authors.lastname: Fongcom
authors.affiliation: Faculty of Veterinary Medicine, University of Montreal, Saint-Hyacinthe, QC, Canada J2S 2M2.
authors.forename: Marcelo
authors.initials: M
authors.lastname: Gottschalk
authors.affiliation: Microbiology Laboratory, Maharaj Nakorn Chiang Mai Hospital, Chiang Mai 50200, Thailand.
authors.forename: Banyong
authors.initials: B
authors.lastname: Khanthawa
authors.affiliation: Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
authors.forename: Volaluk
authors.initials: V
authors.lastname: Supajatura
authors.affiliation: Department of Animal Hygiene, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Aomori 034-8628, Japan.
authors.forename: Shinji
authors.initials: S
authors.lastname: Takai
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