title: A new spanner in the works of bacterial transcription.
abstract: A promising molecular target that is unlikely to develop antibiotic resistance has been identified in bacteria.
authors.affiliation: Kristine B Arnvig is in the Institute for Structural and Molecular Biology, University College London, London, United Kingdom k.arnvig@ucl.ac.uk.
authors.forename: Kristine B
authors.initials: KB
authors.lastname: Arnvig
authors.forename: Finn
authors.initials: F
authors.lastname: Werner
mesh_terms: D009711:Nucleotides / Q000378:metabolism*; D010456:Peptides, Cyclic / Q000378:metabolism*; D012318:RNA Polymerase I / Q000378:metabolism*
chemical_list: D009711:Nucleotides; D010456:Peptides, Cyclic; D012318:RNA Polymerase I
keywords: RNA polymerase; antibiotics; bipartite inhibitor; inhibitor; transcription; transcription initiation
references.citation: Elife. 2014 Apr 22;3:e02450
references.pmid: 24755292
references.citation: Nat Genet. 2011 Dec 18;44(1):106-10
references.pmid: 22179134
references.citation: Trends Biochem Sci. 2004 Apr;29(4):159-60
references.pmid: 15124627
references.citation: Nat Rev Microbiol. 2011 Feb;9(2):85-98
references.pmid: 21233849
references.citation: Biochem Pharmacol. 2006 Mar 30;71(7):919-29
references.pmid: 16289393
references.citation: Eur J Biochem. 2004 Aug;271(15):3146-54
references.pmid: 15265034
references.citation: Bioorg Med Chem Lett. 2005 Aug 15;15(16):3748-52
references.pmid: 15990299
references.citation: J Antibiot (Tokyo). 2004 Mar;57(3):210-7
references.pmid: 15152807