title: [Surveillance and diagnostic values of ultrasound, computed tomography and magnetic resonance imaging follow-ups in malignant transformation of cirrhotic nodules].
abstract: OBJECTIVE
  To explore the surveillance and diagnostic values of ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI) follow-ups in malignant transformation of cirrhotic nodules so as to improve the diagnostic accuracy of early hepatocellular carcinoma (HCC) with liver cirrhosis.
  
  
  METHODS
  Retrospective analyses were conducted for US, CT and MRI features of 96 HCC patients confirmed by pathological examination or treatment.
  
  
  RESULTS
  All patients (145 lesions) underwent US, CT, MRI examinations during follow-ups.US detected 62 lesions (42.6%) and 90 lesions on enhanced CT (62.1%) presented "fast-in fast-out" enhancement, pseudocapsule, progressive enlargement or increasing numbers in a short time. And 138 nodules on MRI (95.2%) manifested as decreased T1WI signal, increased T2WI and DWI signal, "nodule in nodule" on T2WI, fatty degeneration, change of enhancement patterns, pseudocapsule, progressive enlargement or increased number in a short time.
  
  
  CONCLUSIONS
  MRI offers obvious advantages over CT and US (P < 0.05). US may serve as a routine follow-up mean for cirrhotic patients. Once lesions are found, enhanced CT and/or MRI should be performed for confirming a diagnosis. Cirrhotic patients without HCC should undergo MRI regularly to diagnose HCC earlier.
authors.affiliation: Department of Rdiology, Lishui Central Hospital, Lishui 323000, China. Email: jjstcty@sina.com.
authors.forename: Jiansong
authors.initials: J
authors.lastname: Ji
authors.forename: Hongyuan
authors.initials: H
authors.lastname: Yang
authors.forename: Zufei
authors.initials: Z
authors.lastname: Wang
authors.forename: Chenying
authors.initials: C
authors.lastname: Lu
authors.forename: Junguo
authors.initials: J
authors.lastname: Hui
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis* / Q000000981:diagnostic imaging; D042241:Early Diagnosis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008103:Liver Cirrhosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology*; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography