title: [Clinical research of no use of antibiotics in patients undergoing tension-free repair with incarcerated inguinal hernia].
abstract: OBJECTIVE
  To explore the safety in inguinal incarcerated hernia repair without use of antibiotics.
  
  
  METHODS
  Retrospective statistical analysis was performed for a total 326 patients with inguinal incarcerated hernia repair at our hospital from January 2011 to July 2013. They were divided into 2 groups of non-using (n = 192) and using (n = 134) antibiotics. Statistical analysis of early postoperative infection was performed for two groups.
  
  
  RESULTS
  The total incision infection had no statistical difference between two groups (7.29% (14/192) vs 3.73% (5/134), 0.52% (1/192) vs 1.49% (2/134), both P > 0.05). Further comparison of leukocyte count and neutrophil count at Day 3 showed no inter-group statistical difference ((7.9 ± 0.6) ×10(9) vs (7.8 ± 0.7) ×10(9)/L, (4.9 ± 0.5)×10(9) vs (5.0 ± 0.5) ×10(9)/L; U = 1.344, 1.777; P = 0.180, 0.077).
  
  
  CONCLUSIONS
  It is unnecessary to use preventive antibiotics in patients undergoing tension-free repair with incarcerated inguinal hernia without high-risk infection or bowel necrosis.
authors.affiliation: Department of General Surgery, Anhui Medical University Affiliated Hospital, Hefei Second People's Hospital, Hefei 230011, China. Email:wenzhong_bao@126.com.
authors.forename: Wenzhong
authors.initials: W
authors.lastname: Bao
authors.forename: Gaochao
authors.initials: G
authors.lastname: Zhou
authors.forename: Dawei
authors.initials: D
authors.lastname: Tang
authors.forename: Jiawen
authors.initials: J
authors.lastname: Wang
authors.forename: Maoming
authors.initials: M
authors.lastname: Xiong
authors.forename: Xiangling
authors.initials: X
authors.lastname: Meng
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019072:Antibiotic Prophylaxis; D005260:Female; D006552:Hernia, Inguinal / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013526:Surgical Mesh; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents