title: Lumbar spinal stenosis: therapeutic options review.
abstract: Lumbar spinal stenosis (LSS) functionally impacts significant numbers of Americans per year. Current estimates place the number of Americans suffering from senescent lumbar spinal stenosis at 400,000. The prevalence of this disorder in patients ranging from 60 to 69 years of age is very high. Forty-seven percent of this age group have mild to moderate stenosis, and 19.7% have severe stenosis. As the baby boomer generation gets older, 10,000 individuals attain the age of 65 years every day in United States. LSS is becoming very common and will be a major healthcare issue as the population ages. Although LSS is not life threatening, it can cause substantial disability with limitations to performing daily activities, and thus, the associated negative impact on quality of life (QOL). This article reviews the pathophysiology and current treatment options for LSS, focusing on evidence-based treatment options.
authors.affiliation: Department of Pain Management, Cleveland Clinic, Cleveland, Ohio, U.S.A.
authors.forename: Shrif
authors.initials: S
authors.lastname: Costandi
authors.forename: Bohdan
authors.initials: B
authors.lastname: Chopko
authors.forename: Mena
authors.initials: M
authors.lastname: Mekhail
authors.forename: Teresa
authors.initials: T
authors.lastname: Dews
authors.forename: Nagy
authors.initials: N
authors.lastname: Mekhail
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000700:Analgesics / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D019299:Decompression, Surgical / Q000379:methods*; D006293:Health Promotion / Q000379:methods; D006801:Humans; D007268:Injections, Epidural / Q000379:methods; D008159:Lumbar Vertebrae / Q000601:surgery*; D026741:Physical Therapy Modalities; D011788:Quality of Life; D013130:Spinal Stenosis / Q000175:diagnosis / Q000628:therapy*
chemical_list: D000305:Adrenal Cortex Hormones; D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal
keywords: ligamentum flavum; low back pain; lumbar spinal stenosis; minimally invasive lumbar decompression; review; treatment