title: Multifunctional nanostructured materials for multimodal cancer imaging and therapy.
abstract: This paper reviews the recent research and development of multifunctional nanostructured materials for multimodal imaging and therapy. The biomedical applications for multifunctional imaging, diagnosis and therapy are discussed for several nanostructured materials such as polymeric nanoparticles, magnetic nanoparticles, gold nanomaterials, carbon materials, quantum dots and silica nanoparticles. Due to the unique features of nanostructured materials including the large surface area, structural diversity, multifunctionality, and long circulation time in blood, these materials have emerged as attractive preferences for optimized therapy. Multimodal imaging can be introduced to nanostructured materials for precise and fast diagnosis of cancer, which overcomes the shortcoming of single-imaging modality. Meanwhile, nanostructured materials can be also used to deliver therapeutic agents to the disease site in order to accomplish multimodal imaging and simultaneous diagnosis and therapy.
authors.forename: Jinfeng
authors.initials: J
authors.lastname: Liao
authors.forename: Tingting
authors.initials: T
authors.lastname: Qi
authors.forename: Bingyang
authors.initials: B
authors.lastname: Chu
authors.forename: Jinrong
authors.initials: J
authors.lastname: Peng
authors.forename: Feng
authors.initials: F
authors.lastname: Luo
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Qian
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000627:therapeutic use; D006801:Humans; D057054:Molecular Imaging / Q000379:methods*; D058990:Molecular Targeted Therapy / Q000379:methods*; D064847:Multimodal Imaging / Q000379:methods*; D053758:Nanoparticles / Q000737:chemistry* / Q000627:therapeutic use*; D009369:Neoplasms / Q000175:diagnosis* / Q000628:therapy*
chemical_list: D000970:Antineoplastic Agents