title: [Analysis of intracranial infection factors after transnasal endoscopic repair of cerebrospinal fluid rhinorrhea].
abstract: OBJECTIVE
  To analyze the factors of intracranial infection after transnasal endoscopic repair of cerebrospinal fluid rhinorrhea.
  
  
  METHODS
  One hundred and seventy-three patients who accepted transnasal endoscopic repair of cerebrospinal fluid rhinorrhea were retrospectively analyzed. The intracranial infection factors was analyzed by Logistic regression analysis with SPSS 17.0 software.
  
  
  RESULTS
  Postoperative infection was found in 17 cases among 173 patients, the infection rate was 9.83%. The unsuccessful transnasal endoscopic repair of cerebrospinal fluid rhinorrhea (χ(2) = 6.89, P = 0.001) , the defective diameter of skull base (χ(2) = 9.98, P = 0.001) and medical history of intracranial infection (χ(2) = 11.08, P = 0.001) were infection factors after transnasal endoscopic repair of cerebrospinal fluid rhinorrhea (all P < 0.05), while sex, age, the site of defection, the aetiological agent, longer application of antibiotics before or after operation and the use of artificial material had no obvious effect (all P > 0.05).
  
  
  CONCLUSIONS
  Intracranial infection after transnasal endoscopic repair of cerebrospinal fluid rhinorrhea is affected by many factors, such as the unsuccessful transnasal endoscopic repair of cerebrospinal fluid rhinorrhea, the defective diameter of skull base and medical history of intracranial infection.
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Tianjin Huanhu Hospital, Tianjin 300060, China.
authors.forename: Huanxin
authors.initials: H
authors.lastname: Yu
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Tianjin Huanhu Hospital, Tianjin 300060, China. Email: liugang60@aliyun.com.
authors.forename: Gang
authors.initials: G
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001927:Brain Diseases / Q000209:etiology*; D002559:Cerebrospinal Fluid Rhinorrhea / Q000601:surgery*; D002648:Child; D004724:Endoscopy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007239:Infections / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D059747:Nasal Surgical Procedures / Q000009:adverse effects*; D012189:Retrospective Studies; D055815:Young Adult