title: Thyroid nodules with suspicious ultrasound findings: the role of ultrasound-guided core needle biopsy.
abstract: The aim of this study was to evaluate the value of core needle biopsy (CNB) in the diagnosis of sonographically suspicious thyroid nodules. We retrospectively reviewed 997 patients with sonographically suspicious thyroid nodules who underwent CNB using pathological results as gold standard. In our result, the accuracy of CNB was 98.0%, and its area under the receiver operating characteristic curve was 0.981. The inconclusive result was in 22 (6.0%) of CNBs. Therefore, CNB demonstrates high rates of conclusive and accurate diagnosis in sonographically suspicious thyroid nodules, which may reduce repeat fine needle aspiration, diagnostic surgery, and unnecessary follow-up.
authors.affiliation: Department of Ultrasound, General Hospital of Chinese PLA, No.28, Fuxing Road, Haidian District, Beijing, China, (100853). Electronic address: owsifanduizhe@126.com.
authors.forename: Mingbo
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Department of Ultrasound, General Hospital of Chinese PLA, No.28, Fuxing Road, Haidian District, Beijing, China, (100853). Electronic address: zhangyaner301@126.com.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Ultrasound, General Hospital of Chinese PLA, No.28, Fuxing Road, Haidian District, Beijing, China, (100853). Electronic address: ouhe1919@sina.com.
authors.forename: Shuai
authors.initials: S
authors.lastname: Fu
authors.affiliation: Department of Ultrasound, General Hospital of Chinese PLA, No.28, Fuxing Road, Haidian District, Beijing, China, (100853). Electronic address: lvjin8912@163.com.
authors.forename: Faqin
authors.initials: F
authors.lastname: Lv
authors.affiliation: Department of Ultrasound, General Hospital of Chinese PLA, No.28, Fuxing Road, Haidian District, Beijing, China, (100853). Electronic address: txiner@vip.sina.com.
authors.forename: Jie
authors.initials: J
authors.lastname: Tang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D044963:Biopsy, Fine-Needle; D062005:Biopsy, Large-Core Needle; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012372:ROC Curve; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging*; D016606:Thyroid Nodule / Q000000981:diagnostic imaging*; D014463:Ultrasonography; D055815:Young Adult
keywords: Core needle biopsy; Nodule; Thyroid; Ultrasound