title: Application of two-dimensional electrophoresis and mass spectrometry to screen endometriosis-related proteins.
abstract: The aim of the present study was to detect the differences in the protein expression between Uyghur females with or without endometriosis (EM). The two dimensional (2D) gel images of proteins extracted from the serum of Uyghur and Han females with EM and the controls were analyzed using Phoretix 2D software, and the differentially expressed proteins were identified primarily by database query. Having compared the reproducible 2D gel images of proteins from the serum of Uihgur and Han females with and without EM, 13 differentially expressed proteins were obtained from Uyghur females and eight differentially expressed proteins were obtained from Han females. The present study demonstrated ethnic differences in gene and protein expression between Uyghur and Han females with EM.
authors.affiliation: Gynecology Department, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, P.R. China.
authors.forename: Hanikezi
authors.initials: H
authors.lastname: Tuerxun
authors.affiliation: Department of Obstetrics, Xinjiang Uygur Autonomous Region People's Hospital, Urumqi, Xinjiang 830001, P.R. China.
authors.forename: Yanmei
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Gynecology Department, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, P.R. China.
authors.forename: Fei
authors.initials: F
authors.lastname: Ji
authors.affiliation: Department of Gynecology, Shanghai Dongfang Hospital, Shanghai 200120, P.R. China.
authors.forename: Aixingzi
authors.initials: A
authors.lastname: Aili
authors.affiliation: Gynecology Department, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, P.R. China.
authors.forename: Xinhua
authors.initials: X
authors.lastname: Yang
authors.affiliation: Gynecology Department, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, P.R. China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Ding
mesh_terms: D000293:Adolescent; D000328:Adult; D044466:Asian People; D001798:Blood Proteins / Q000032:analysis*; D002681:China; D015180:Electrophoresis, Gel, Two-Dimensional; D004715:Endometriosis / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D055815:Young Adult
chemical_list: D001798:Blood Proteins