title: [Methylphenidate use in dogs with attention deficit hyperactivity disorder (ADHD). A case report of a Weimaraner bitch].
abstract: A 10-month-old Weimaraner bitch was presented at the practice exhibiting agitation, hyperactivity, inability to learn and attention deficit. The diagnostic findings were excessive, long-lasting acoustic and locomotory activity with unexpected inappropriate reactions. Hematological and biochemical blood analyses did not demonstrate abnormal findings. The first attempts at behavioral therapy and fluoxetine application were unsatisfactory. Therefore, a test was conducted with medication for central nervous system stimulation to confirm a diagnosis of hyperkinesis. Following the diagnosis of attention deficit hyperactivity disorder, the therapy was continued with behavioral modifications, with special consideration of rehabituation and resocialization as well as the use of methylphenidate. During the course of the therapy the bitch developed hyperactivity again when on heat. After changing the dosage of methylphenidate and additionally using dog appeasing pheromone, the behavior of the bitch became normal after 8 days. Two months later endoscopic ovarioectomy was performed. Twelve months after the initial use of methylphenidate the medication could be discontinued completely and the dog's behavior was normal. The methylphenidate dosage used during this therapy was much higher than recommended in the literature.
authors.affiliation: Pasquale Piturru, Dr. med. vet., M. Sc., Elmshorner Straße 47a, 25421 Pinneberg, E-Mail: dr.p@piturru.de, www.piturru.de.
authors.forename: P
authors.initials: P
authors.lastname: Piturru
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D000697:Central Nervous System Stimulants / Q000627:therapeutic use*; D004283:Dog Diseases / Q000188:drug therapy* / Q000503:physiopathology; D004285:Dogs; D005260:Female; D006948:Hyperkinesis / Q000188:drug therapy / Q000503:physiopathology / Q000662:veterinary*; D008774:Methylphenidate / Q000627:therapeutic use*
chemical_list: D000697:Central Nervous System Stimulants; D008774:Methylphenidate
keywords: Behavioral disorder; dog appeasing pheromone (DAP); hyperactivity; hyperkinesis; methylphenidate