title: [A case of pneumatosis cystoides intestinalis secondary to sunitinib treatment for renal cell carcinoma].
abstract: A 78-year-old man was diagnosed as having right renal cell carcinoma (RCC) with metastasis to the right lung. He received sunitinib and the treatment reduced the size of both RCC and lung metastasis. Then he received right radical nephrectomy. The pathological diagnosis was clear cell RCC. After the initial surgery, he was diagnosed with polymyalgia rheumatic and steroid therapy was started. During follow-up, local recurrence was discovered and sunitinib was then started at a dose of 25 mg/day. Two months after the treatment, abdominal computed tomography (CT) revealed colonic pneumatosis cystoides intestinalis. Administration of sunitinib was stopped and the patient was observed carefully without pursuing surgical intervention. A follow-up CT demonstrated resolution of the colonic pnumatosis.
authors.affiliation: The Department of Urology, Yokohama Municipal Citizen's Hospital.
authors.forename: Shinji
authors.initials: S
authors.lastname: Ohtake
authors.affiliation: The Department of Urology, Yokohama Municipal Citizen's Hospital.
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Namura
authors.affiliation: The Department of Urology, Yokohama Municipal Citizen's Hospital.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Fujikawa
authors.affiliation: The Department of Urology, Yokohama Municipal Citizen's Hospital.
authors.forename: Takuto
authors.initials: T
authors.lastname: Sawada
authors.affiliation: The Department of Urology, Yokohama Municipal Citizen's Hospital.
authors.forename: Junichi
authors.initials: J
authors.lastname: Ohta
authors.affiliation: The Department of Urology, Yokohama Municipal Citizen's Hospital.
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Moriyama
authors.affiliation: The Department of Pathology, Yokohama Municipal Citizen's Hospital.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Hayashi
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002292:Carcinoma, Renal Cell / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D007211:Indoles / Q000009:adverse effects*; D007680:Kidney Neoplasms / Q000188:drug therapy* / Q000601:surgery; D008297:Male; D011006:Pneumatosis Cystoides Intestinalis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D011758:Pyrroles / Q000009:adverse effects*; D000077210:Sunitinib; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents; D007211:Indoles; D011758:Pyrroles; D000077210:Sunitinib