title: Management of Bleeding Pelvic Fractures.
abstract: BACKGROUND
  In patients with severe pelvic fractures, exsanguinating hemorrhage represents the major cause of death within the first 24 h. Despite advances in management, the mortality rate in these patients remains significantly high. Recently, multiple treatment algorithms have been proposed for patients with severe pelvic fractures; however, the optimal modalities in particular in the hemodynamically unstable patient are still a matter of lively debate.This review article focuses on the recent body of knowledge on the different treatment options in patients with severe pelvic fractures and proposes the possible role of each modality in the management of these patients.
  
  
  METHODS
  The MEDLINE database was searched for medical literature addressing the management of severe pelvic fractures with specific attention given to recent, clinically relevant publications.
  
  
  RESULTS
  Angiography and embolization have emerged as excellent methods for addressing arterial bleeding. Mechanical pelvic stabilization and surgical hemostasis by pelvic packing, on the other hand, may effectively control venous bleeding and bleeding from the fractured bony surface. However, since there is no precise way to determine the major source of bleeding that is responsible for the hemodynamic instability, controversy remains over the timing and optimal order of angiography, mechanical pelvic stabilization, and packing.
  
  
  CONCLUSIONS
  The author's own approach to these patients includes angiographic embolization as a first-line treatment only in hemodynamically stable patients with an arterial blush seen in the computed tomography scan, indicating acute arterial bleeding. Hemodynamically unstable patients are immediately transferred to the operating room, where pelvic packing and mechanical stabilization of the pelvic ring are carried out. Optionally, a subsequent postoperative angio-embolization is performed if signs of further bleeding remain present.
authors.affiliation: Department of Trauma, Hand and Reconstructive Surgery, University Hospital, Goethe University Frankfurt am Main, Germany marzi@trauma.uni-frankfurt.de.
authors.forename: I
authors.initials: I
authors.lastname: Marzi
authors.affiliation: Department of Trauma, Hand and Reconstructive Surgery, University Hospital, Goethe University Frankfurt am Main, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Lustenberger
keywords: Pelvic ring fracture; angiography; embolization; external fixation; hemodynamic instability; management; pelvic C-clamp; pelvic packing