title: Perforation of enteric duplication during chemotherapy for osteosarcoma.
abstract: A 9-year-old boy undergoing chemotherapy for conventional osteosarcoma complained of severe abdominal pain associated with rebound tenderness and muscular defense. Abdominal computed tomography indicated intraperitoneal free air. On surgical investigation, a diverticulum-like lesion, perforated at the base, was found on the sidewall of the ileum. The anatomic location of the lesion was indicative of enteric duplication. Although the frequency of complications is very rare, perforations of the digestive tract should be considered in patients suffering severe abdominal pain while receiving chemotherapy.
authors.affiliation: Department of Pediatrics, Kyoto University, Kyoto, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Morishima
authors.forename: Itaru
authors.initials: I
authors.lastname: Kato
authors.forename: Katsutsugu
authors.initials: K
authors.lastname: Umeda
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Hiramatsu
authors.forename: Shinya
authors.initials: S
authors.lastname: Okamoto
authors.forename: Akihiro
authors.initials: A
authors.lastname: Furuta
authors.forename: Takeharu
authors.initials: T
authors.lastname: Nakamata
authors.forename: Souichi
authors.initials: S
authors.lastname: Adachi
authors.forename: Toshio
authors.initials: T
authors.lastname: Heike
authors.forename: Ken-ichiro
authors.initials: K
authors.lastname: Watanabe
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D001859:Bone Neoplasms / Q000150:complications* / Q000188:drug therapy*; D002648:Child; D006801:Humans; D007077:Ileal Diseases / Q000139:chemically induced*; D007416:Intestinal Perforation / Q000139:chemically induced*; D007422:Intestines / Q000002:abnormalities*; D008297:Male; D012516:Osteosarcoma / Q000150:complications* / Q000188:drug therapy*; D013977:Tibia
chemical_list: D000970:Antineoplastic Agents
keywords: chemotherapy; enteric duplication; gastrointestinal disturbance; osteosarcoma; perforation