title: Detection rate of prostate cancer on the basis of the vienna nomogram: a singapore study.
abstract: OBJECTIVE
  The purpose of this study was to determine the efficacy of the Vienna nomogram prostate biopsy model in the detection of prostate cancer in our local population. We also assessed the incidence of complications from using such a template.
  
  
  METHODS
  From January 2006 to June 2007, 120 men with either elevated prostate-specific antigen (PSA) scores (>4 ng/mL) and/or abnormal digital rectal examination were enrolled prospectively to undergo extraction of 6 to 18 cores for transrectal ultrasound-guided prostate biopsy, as indicated by the Vienna nomogram.
  
  
  RESULTS
  The mean age was 62.6±8.3 years (range, 40-86 years). The mean PSA score was 13.42 ng/mL. The mean number of cores obtained was 9.68±3.1. According to the Vienna nomogram, 27 out of a total of 120 patients had prostate cancer, for a detection rate of 22.5%. In the group of patients with PSA scores <10 ng/mL, the detection rate was 14.9% (14 of 94 patients). The group of patients with PSA scores >10 ng/mL had a detection rate of 50% (13 of 26). The complication rate in our study was 7.5%.
  
  
  CONCLUSIONS
  With the use of the Vienna nomogram, our prostate cancer detection rate is comparable to previously published data for Asian patients. This nomogram offers an easy tool with which to select the optimal number of prostate biopsy cores to be taken on the basis of patient age and total prostate volume. With this biopsy strategy, we also have found that the complication rate from prostate biopsy is low.
authors.affiliation: Department of Urology, Changi General Hospital, Singapore.
authors.forename: Jin Kiat
authors.initials: JK
authors.lastname: Teo
authors.affiliation: Department of Urology, Changi General Hospital, Singapore.
authors.forename: Beow Kiong
authors.initials: BK
authors.lastname: Poh
authors.affiliation: Department of Urology, Changi General Hospital, Singapore.
authors.forename: Foo Cheong
authors.initials: FC
authors.lastname: Ng
authors.affiliation: Department of Urology, Raffles Hospital, Singapore.
authors.forename: Yan Kit
authors.initials: YK
authors.lastname: Fong
keywords: Biopsy; Nomogram; Prostate neoplasms
references.citation: BJU Int. 2011 Jul;108(2):204-8
references.pmid: 21087452
references.citation: J Urol. 1998 Dec;160(6 Pt 1):2121-5
references.pmid: 9817336
references.citation: Urology. 1997 Oct;50(4):562-6
references.pmid: 9338732
references.citation: J Urol. 2003 Jan;169(1):130-5
references.pmid: 12478120
references.citation: BJU Int. 2004 Aug;94(3):307-10
references.pmid: 15291857
references.citation: J Urol. 2001 Sep;166(3):856-60
references.pmid: 11490233
references.citation: J Urol. 1997 Jan;157(1):199-202; discussion 202-3
references.pmid: 8976250
references.citation: J Urol. 2003 Jan;169(1):125-9
references.pmid: 12478119
references.citation: Urology. 2003 Jan;61(1):161-6
references.pmid: 12559289
references.citation: J Urol. 2000 Apr;163(4):1144-8; discussion 1148-9
references.pmid: 10737484
references.citation: Clin Prostate Cancer. 2003 Sep;2(2):115-8
references.pmid: 15040873
references.citation: Asian J Surg. 2002 Jul;25(3):238-43
references.pmid: 12376223
references.citation: Urology. 1998 May;51(5A Suppl):125-30
references.pmid: 9610567
references.citation: Urology. 1995 Dec;46(6):831-6
references.pmid: 7502425
references.citation: Urology. 2006 Feb;67(2):333-6
references.pmid: 16461083
references.citation: Eur Urol. 2002 Aug;42(2):93-103
references.pmid: 12160578
references.citation: Jpn J Clin Oncol. 1998 Nov;28(11):666-72
references.pmid: 9861233
references.citation: J Urol. 2005 Oct;174(4 Pt 1):1256-60; discussion 1260-1; author reply 1261
references.pmid: 16145388