Docetaxel extravasation results in significantly delayed and relapsed skin injury: A case report.
Chemotherapeutic agents can result in extravasation, which is considered to be a serious complication. The increasing number of exposures to different cytotoxic agents experienced by each patient may enhance the prevalence of this complication. Docetaxel is widely used in the treatment of numerous solid tumors. Thus, the current report presents the case of a breast cancer patient who developed a significantly delayed skin reaction one day after docetaxel extravasation, a rare skin manifestation, and relapsed one week subsequently. This unusual clinical presentation is an indicator that practitioners are required to carefully monitor the patient for further cutaneous reactions in the weeks following extravasation to observe any additional adverse reactions.
Division of Hemato-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung 20445, Taiwan, R.O.C.
Pei-Hung
PH
Chang
Department of Pharmacy, Chang Gung Memorial Hospital, Keelung 20445, Taiwan, R.O.C.
Mei-Ti
MT
Wang
Department of Pharmacy, Chang Gung Memorial Hospital, Keelung 20445, Taiwan, R.O.C.
Yi-Hua
YH
Chen
Department of Pharmacy, Chang Gung Memorial Hospital, Keelung 20445, Taiwan, R.O.C.
Yu-Ying
YY
Chen
Division of Hemato-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung 20445, Taiwan, R.O.C. ; Cancer Center, Chang Gung Memorial Hospital, Keelung 20445, Taiwan, R.O.C.
Cheng-Hsu
CH
Wang
chemotherapy; docetaxel; extravasation