Eye movements as a probe of corollary discharge function in schizophrenia.
Nearly every movement made by every animal is accompanied by a corollary discharge, a signal sent from the motor to sensory regions of its brain. Corollary discharges are a crucial mechanism by which the brain monitors its own actions, and there is some evidence that they are impaired in people with schizophrenia. Here, I briefly review this evidence and suggest that eye movements are a particularly valuable tool for assessing the role of corollary discharges in schizophrenia.
McGill University , Montreal, Quebec, Canada H3A 2B4.
Christopher C
CC
Pack
D000344:Afferent Pathways / Q000503:physiopathology*; D000818:Animals; D001921:Brain / Q000503:physiopathology*; D004594:Electrophysiology; D005133:Eye Movements / Q000502:physiology*; D006801:Humans; D012559:Schizophrenia / Q000473:pathology*