High colonization rate and prolonged shedding of Clostridium difficile in pediatric oncology patients.
Surveillance testing for Clostridium difficile among pediatric oncology patients identified stool colonization in 29% of patients without gastrointestinal symptoms and in 55% of patients with prior C. difficile infection (CDI). A high prevalence of C. difficile colonization and diarrhea complicates the diagnosis of CDI in this population.
Department of Pediatric Infectious Diseases Department of Epidemiology.
Samuel R
SR
Dominguez
Department of Epidemiology.
Susan A
SA
Dolan
Department of Epidemiology.
Kelly
K
West
Epidemic Intelligence Service Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Raymund B
RB
Dantes
Epidemic Intelligence Service Colorado Department of Public Health and Environment, Denver.
Erin
E
Epson
Department of Pediatric Hematology/Oncology/Bone Marrow Transplant Department of Nursing.
Deborah
D
Friedman
Department of Pathology and Laboratory Medicine.
Cynthia A
CA
Littlehorn
Department of Pathology and Laboratory Medicine.
Lesley E
LE
Arms
Department of Pediatric Hematology/Oncology/Bone Marrow Transplant Department of Nursing.
Karen
K
Walton
Department of Pediatric Hematology/Oncology/Bone Marrow Transplant Department of Nursing.
Ellen
E
Servetar
Department of Adult Infectious Diseases, Children's Hospital Colorado and University of Colorado School of Medicine, Aurora.
Daniel N
DN
Frank
Department of Adult Infectious Diseases, Children's Hospital Colorado and University of Colorado School of Medicine, Aurora.
Cassandra V
CV
Kotter
Department of Pathology and Laboratory Medicine.
Elaine
E
Dowell
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Carolyn V
CV
Gould
Department of Pediatric Hematology/Oncology/Bone Marrow Transplant.
Joanne M
JM
Hilden
Department of Pediatric Infectious Diseases Department of Epidemiology.
James K
JK
Todd
D000293:Adolescent; D057138:Bacterial Shedding; D002648:Child; D002675:Child, Preschool; D016360:Clostridioides difficile / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology; D003967:Diarrhea; D005243:Feces / Q000382:microbiology; D006801:Humans; D007223:Infant; D009369:Neoplasms / Q000150:complications*; D010372:Pediatrics; D015995:Prevalence; D055815:Young Adult
Clostridium difficile; colonization; oncology; pediatric; surveillance