[Low level of 25-OH-vitamin D as a marker of critical ischemia in case of diabetic foot syndrome].
It was done the prospective study of the examination results of 40 patients with diabetes mellitus. All patients were divided into 2 groups for study of 25-OH-vitamin D effect, cholesterol, triglycerides in blood serum on the nature of diabetes mellitus. The first group included patients with ulcero-necrotic injuries in case of neuro-ischemic forms of diabetic foot syndrome. The second group included patients without such injuries. It was significantly determined that there was more neuro-ischemic injuries in case of 25-OH-vitamin D level less than 30 nmol/l. Injuries are connected with reduction of arterial inflow because of osslusive-stenotic lesions of arteries. 25-OH-vitamin D level less than 30 nmol/l is a marker of neuro-ischemic injuries of foot in case of diabetes mellitus. This indication is more specific than cholesterol and triglycerides levels.
I N
IN
Ignatovich
G G
GG
Kondratenko
Iu V
IuV
Dobrovol'skaia
D015652:25-Hydroxyvitamin D 2 / Q000097:blood*; D000328:Adult; D015415:Biomarkers / Q000097:blood; D002784:Cholesterol / Q000097:blood*; D003920:Diabetes Mellitus / Q000097:blood / Q000503:physiopathology; D017719:Diabetic Foot / Q000097:blood / Q000209:etiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D007511:Ischemia / Q000097:blood / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013223:Statistics as Topic; D014280:Triglycerides / Q000097:blood*
D015415:Biomarkers; D014280:Triglycerides; D015652:25-Hydroxyvitamin D 2; D002784:Cholesterol