The effect of a MspI polymorphism at the porcine pituitary specific transcription factor (PIT-1) gene on backfat thickness.
In the present study the association between a MspI polymorphism in the porcine PIT-1 gene and backfat thickness in Belgian slaughter pigs was investigated. The polymorphism was analysed with an improved PCR-RFLP test, using primers chosen on the sequence of intron 3 of the PIT-1 gene. The polymorphism was confirmed in a number of dam breeds (Landrace, Large White, Synthetic Lines) and in the main Belgian terminal sire breed Piétrain. In crossbred progeny (n = 185), a mixed animal model analysis indicated that the MspI D allele could possibly be associated with a higher backfat thickness, but the effect only approached significance (P = 0.06). In addition, this effect has to be interpreted carefully in view of the reverse allelic effects between studies and the low number of CC homozygous animals in this study.
S
S
De Smet
J
J
Depuydt
H
H
Bovenhuis
D J
DJ
de Koning
L
L
Herman
D050154:Adiposity; D000818:Animals; D001483:Base Sequence; D001823:Body Composition; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction / Q000662:veterinary; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D034421:Sus scrofa / Q000235:genetics / Q000502:physiology*; D050817:Transcription Factor Pit-1 / Q000235:genetics* / Q000378:metabolism
D050817:Transcription Factor Pit-1