Fetal maxillary and mandibular length in normal pregnancies from 11 weeks' to 13(+6) weeks' gestation: a Taiwanese study.
OBJECTIVE
This study aims to establish the normal range of maxillary and mandibular lengths within the Taiwanese population at 11(+0) weeks to 13(+6) weeks of gestation in normal singleton pregnancy as a reference value for prenatal ultrasonographic examinations.


METHODS
We examined nuchal translucency in 269 normal singleton pregnancies, with the gestational age ranging from 11 weeks to 13(+6) weeks in this study. Fetal biometric measurements, with an emphasis on maxillary and mandibular lengths, were obtained from the patients during consecutive routine prenatal ultrasonographic examinations.


RESULTS
Maxillary and mandibular lengths were recorded successfully in 191 patients and 179 patients, respectively. The mean maternal age was 31 years (range 19-45 years), with a corresponding gestational age of 12 + 4 weeks (range, 11(+0)-13(+6) weeks). A first-degree correlation was found to exist between the gestational age and maxillary length (r = 0.596; p < 0.0001; y = 1.491 × GA - 10.523) as well as mandibular length (r = 0.465; p < 0.0001; y = 1.050 × GA - 6.50).


CONCLUSIONS
Normative data for ultrasonographic measurements of maxillary and mandibular lengths within the Taiwanese population were presented. Our data can serve as a reference value in congenital anomaly screening during prenatal examination.
Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan.
Ing-Luen
IL
Shyu
Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; National Yang-Ming University, School of Medicine, Taipei, Taiwan.
Ming-Jie
MJ
Yang
Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan; Taipei Mackay Memorial Hospital, Taipei, Taiwan; Mackay Medicine, Nursing and Management College, Taipei, Taiwan.
Hsing-I
HI
Wang
Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; National Yang-Ming University, School of Medicine, Taipei, Taiwan.
Peng-Hui
PH
Wang
Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; National Yang-Ming University, School of Medicine, Taipei, Taiwan.
Chia-Ming
CM
Chang
Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; National Yang-Ming University, School of Medicine, Taipei, Taiwan.
Chi-Mou
CM
Juang
Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; National Yang-Ming University, School of Medicine, Taipei, Taiwan.
Yi-Jen
YJ
Chen
Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; National Yang-Ming University, School of Medicine, Taipei, Taiwan.
Huann-Cheng
HC
Horng
Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan.
Chia-Chien
CC
Chen
Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; National Yang-Ming University, School of Medicine, Taipei, Taiwan.
Jen-Yu
JY
Tseng
Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; National Yang-Ming University, School of Medicine, Taipei, Taiwan; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.
Pi-Lin
PL
Sung
Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; National Yang-Ming University, School of Medicine, Taipei, Taiwan.
Ming-Shyen
MS
Yen
Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; National Yang-Ming University, School of Medicine, Taipei, Taiwan; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan. Electronic address: zachary.joyce@gmail.com.
Chih-Yao
CY
Chen
Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; National Yang-Ming University, School of Medicine, Taipei, Taiwan.
Kuan-Chong
KC
Chao
D000328:Adult; D044466:Asian People; D005260:Female; D005865:Gestational Age; D006801:Humans; D008334:Mandible / Q000033:anatomy & histology* / Q000196:embryology; D008423:Maternal Age; D008437:Maxilla / Q000033:anatomy & histology* / Q000196:embryology; D008875:Middle Aged; D048208:Nuchal Translucency Measurement / Q000379:methods* / Q000592:standards*; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D012016:Reference Values; D013624:Taiwan; D055815:Young Adult
fetal ultrasound; mandibular bone; maxillary bone; nuchal translucency; prenatal diagnosis