Comment on Laker et al. Exercise prevents maternal high-fat diet-induced hypermethylation of the pgc-1α gene and age-dependent metabolic dysfunction in the offspring. Diabetes 2014;63:1605-1611.
Department of Neuroscience, Uppsala University, Uppsala, Sweden.
Jonathan
J
Cedernaes
Christian
C
Benedict
D000818:Animals; D019175:DNA Methylation; D005260:Female; D009765:Obesity / Q000378:metabolism*; D000071248:Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; D010805:Physical Conditioning, Animal / Q000502:physiology*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000378:metabolism*; D014157:Transcription Factors / Q000378:metabolism*
D000071248:Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; C485290:Ppargc1a protein, mouse; D014157:Transcription Factors