[Ginkgo leaves tablet improved the memory quotient of patients with mild cognitive impairment: a clinical observation].
OBJECTIVE
To observe the effect of Ginkgo Leaves Tablet (GLT) on memory quotient (MQ) of mild cognitive impairment (MCI) patients.


METHODS
One hundred and thirteen patients were randomly assigned to the control group (55 cases) and the treatment group (58 cases). Patients in the control group received dietetic therapy and physical exercises, while those in the treatment group additionally took GLT, 19.2 mg each time, three times daily. The treatment course was 12 months for all. The MQ of all the patients was assessed by WMS-RC before treatment,at 6-month of treatment, and 12-month of treatment.


RESULTS
Compared with the control group, the improvement of MQ increased in the treatment group 0.5 and 1 year after treatment (P < 0.05). The clinical efficiency of MQ obviously increased in the treatment group (48.28% and 50.00%), showing statistical difference when compared with the control group (30.91% and 27.27%, P < 0.05, P < 0.01). There was statistical difference in added scores of recognition, regeneration, understanding, and recitation test at 6-month of treatment and 12-month of treatment between the treatment group and the control group (P < 0.05, P < 0.01).


CONCLUSIONS
GLT was effective in improving MQ of MCI patients, especially in improving recognition, regeneration, understanding, and recitation test.
Zhong-Hai
ZH
Yu
Chun-Yan
CY
Zhang
Bin-Hong
BH
Pu
Shi-Yuan
SY
Xiao
Zhen-Hua
ZH
Dong
Ya-Ming
YM
Li
D000368:Aged; D000369:Aged, 80 and over; D060825:Cognitive Dysfunction / Q000188:drug therapy* / Q000523:psychology*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D020441:Ginkgo biloba / Q000737:chemistry; D006801:Humans; D008297:Male; D008568:Memory; D008875:Middle Aged; D008517:Phytotherapy
D004365:Drugs, Chinese Herbal