Fiber-optic combined FPI/FBG sensors for monitoring of radiofrequency thermal ablation of liver tumors: ex vivo experiments.
We present a biocompatible, all-glass, 0.2 mm diameter, fiber-optic probe that combines an extrinsic Fabry-Perot interferometry and a proximal fiber Bragg grating sensor; the probe enables dual pressure and temperature measurement on an active 4 mm length, with 40 Pa and 0.2°C nominal accuracy. The sensing system has been applied to monitor online the radiofrequency thermal ablation of tumors in liver tissue. Preliminary experiments have been performed in a reference chamber with uniform heating; further experiments have been carried out on ex vivo porcine liver, which allowed the measurement of a steep temperature gradient and monitoring of the local pressure increase during the ablation procedure.
Daniele
D
Tosi
Edoardo Gino
EG
Macchi
Giovanni
G
Braschi
Alfredo
A
Cigada
Mario
M
Gallati
Sandro
S
Rossi
Sven
S
Poeggel
Gabriel
G
Leen
Elfed
E
Lewis
D000818:Animals; D017115:Catheter Ablation / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005336:Fiber Optic Technology / Q000295:instrumentation*; D006498:Hepatectomy / Q000295:instrumentation*; D006979:Hyperthermia, Induced / Q000295:instrumentation; D066298:In Vitro Techniques; D007368:Interferometry / Q000295:instrumentation; D008113:Liver Neoplasms / Q000175:diagnosis / Q000601:surgery*; D008365:Manometry / Q000295:instrumentation*; D016343:Monitoring, Intraoperative / Q000295:instrumentation; D013552:Swine; D018511:Systems Integration; D013817:Thermography / Q000295:instrumentation*; D014159:Transducers