Alopecia universalis during treatment with leflunomide and adalimumab - case report.
Alopecia areata is a non-scarring form of alopecia that can be localized or widespread. Its etiology is unknown, but immunological factors are implicated in its pathogenesis. With the more frequent use of anti TNFα biologic drugs, some alopecia areata cases during their use have been described. We report a case of universal alopecia in a patient with rheumatoid arthritis while using adalimumab and leflunomide.
Santa Casa de São Paulo, São Paulo, SP, Brazil.
Rosana
R
Lazzarini
Santa Casa de São Paulo, São Paulo, SP, Brazil.
Gabriela Cunha
GC
Capareli
Santa Casa de São Paulo, São Paulo, SP, Brazil.
Roberta
R
Buense
Santa Casa de São Paulo, São Paulo, SP, Brazil.
Rute Facchini
RF
Lellis
D000068879:Adalimumab; D000368:Aged; D000505:Alopecia / Q000139:chemically induced* / Q000473:pathology; D061067:Antibodies, Monoclonal, Humanized / Q000009:adverse effects*; D018501:Antirheumatic Agents / Q000009:adverse effects*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D046169:Dermoscopy; D005260:Female; D006801:Humans; D007555:Isoxazoles / Q000009:adverse effects*; D000077339:Leflunomide; D012867:Skin / Q000473:pathology; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
D061067:Antibodies, Monoclonal, Humanized; D018501:Antirheumatic Agents; D007555:Isoxazoles; D014409:Tumor Necrosis Factor-alpha; D000068879:Adalimumab; D000077339:Leflunomide