Inhibitory effect of Ti-Ag alloy on artificial biofilm formation.
Titanium-silver (Ti-Ag) alloy has been improved for machinability and mechanical properties, but its anti-biofilm properties have not been elucidated yet. Thus, this study aimed to evaluate the effects of Ti-Ag alloy on biofilm formation and bacterial viability in comparison with pure Ti, pure Ag and silver-palladium (Ag-Pd) alloy. Biofilm formation on the metal plates was evaluated by growing Streptococcus mutans and Streptococcus sobrinus in the presence of metal plates. Bactericidal activity was evaluated using a film contact method. There were no significant differences in biofilm formation between pure Ti, pure Ag and Ag-Pd alloy, while biofilm amounts on Ti-20% Ag and Ti-25% Ag alloys were significantly lower (p<0.05). In addition, Ti-Ag alloys and pure Ti were not bactericidal, although pure Ag and Ag-Pd alloy killed bacteria. These results suggest that Ti-20% Ag and Ti-25% Ag alloys are suitable for dental material that suppresses biofilm formation without disturbing healthy oral microflora.
Division of Oral Ecology and Biochemistry, Tohoku University Graduate School of Dentistry.
Kazuko
K
Nakajo
Masatoshi
M
Takahashi
Masafumi
M
Kikuchi
Yukyo
Y
Takada
Osamu
O
Okuno
Keiichi
K
Sasaki
Nobuhiro
N
Takahashi
D000497:Alloys; D018441:Biofilms; D012834:Silver / Q000737:chemistry*; D014025:Titanium / Q000737:chemistry*
D000497:Alloys; D012834:Silver; D014025:Titanium