[Application of direct electric current and intravenous ozone therapy in the complex treatment of destructive forms of acute pancreatitis in experiment].
The results of experimental study which have carried out on 40 outbread dogs were analyzed in this thesis. Modeling of destructive pancreatitis in animals has been achieved via canalicular-hypertensive model by S.A. Shalimov. 4 series of experimental study were made to achieve the targeted goal. The first series 10 dogs without treatment, the second series 10 dogs in which conventional conservative therapy was used for the treatment of acute experimental destructive pancreatitis in animals, the third series 10 dogs that underwent intravenous ozone therapy in the complex together with medication therapy, the forth series the effectiveness of combined administration of intravenous ozone therapy and small doses of direct current in 10 dogs was evaluated. Combined administration of small doses of DC and intravenous ozone therapy in the complex treatment of destructive pancreatitis shows antiphlogistic action, favors accelerated rejection of necrotic tissue, remits inflammatory process as well as encourages regeneration process in pancreas whereby allows to decrease the mortality in experimental animals from 60% to 20%.
B S
BS
Zhakiev
A N
AN
Zhumabaeva
A A
AA
Kaliev
G A
GA
Kazbekova
D000681:Amylases / Q000097:blood; D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D003131:Combined Modality Therapy; D004195:Disease Models, Animal; D004285:Dogs; D004599:Electric Stimulation Therapy / Q000379:methods*; D015227:Lipid Peroxidation; D010126:Ozone / Q000008:administration & dosage / Q000627:therapeutic use*; D019283:Pancreatitis, Acute Necrotizing / Q000378:metabolism / Q000473:pathology / Q000628:therapy*
D000975:Antioxidants; D010126:Ozone; D000681:Amylases