Granuloma formation and suspected neuropathic pain in a domestic pigeon (Columba livia) secondary to an oil-based, inactivated Newcastle disease vaccine administered for protection against pigeon paramyxovirus-1.
METHODS
A domestic pigeon developed a sterile granuloma following vaccination with an oil-adjuvant, inactivated La Sota strain of Newcastle disease. The aim of vaccination was to provide protection against pigeon paramyxovirus-1 (PPMV-1), a disease previously considered exotic to Australia. Granuloma formation is considered a rare complication of vaccination against PPMV-1 in pigeons. Clinical signs consistent with neuropathic pain became apparent during the extensive management of the granuloma, which included surgical removal of foreign material, control of the pain and inflammation and protection against antimicrobial contamination.


CONCLUSIONS
PPMV-1 is now considered endemic in Australia and protecting pigeons with vaccination is important. Until a product is registered for use, vaccination remains off-label and the risk of adverse reaction, including sterile granuloma, must be considered.
Brisbane Bird and Exotics Veterinary Service, Cnr Kessels Road and Springfield Street, Macgregor, Queensland, 4109, Australia. melinda@bbevs.com.au.
M L
ML
Cowan
D J
DJ
Monks
S R
SR
Raidal
D000818:Animals; D001315:Australia; D010856:Columbidae; D006099:Granuloma / Q000276:immunology* / Q000628:therapy / Q000821:virology; D006651:Histocytochemistry / Q000662:veterinary; D008297:Male; D009437:Neuralgia / Q000276:immunology* / Q000628:therapy / Q000821:virology; D009521:Newcastle Disease / Q000276:immunology* / Q000517:prevention & control; D009522:Newcastle disease virus / Q000276:immunology*; D015164:Vaccines, Inactivated / Q000009:adverse effects / Q000276:immunology*
D015164:Vaccines, Inactivated
granulomas; neuropathic pain; paramyxovirus; pigeons; vaccination