Subcutaneous abscess due to Pyrenochaeta romeroi in a renal transplant recipient.
An infective aetiology, including fungal infection, should be considered in the differential diagnosis of immunocompromised patients presenting with skin lesions. Dematiaceous fungi are recognised as pathogens in organ transplant recipients. Herein, we describe a rare case of a chronic necrotising granulomatous skin lesion caused by Pyrenochaeta romeroi in a renal transplant recipient, and review the existing literature on the topic. To the best of our knowledge, this is the first report of such a case in Singapore. Recognition of infections caused by dematiaceous fungi is important because some strains are difficult to identify and require special molecular diagnostic techniques. Treatment involves surgical excision and long-term antifungal therapy. Data on the optimal antifungal regimen in such a diagnosis is limited.
Department of Infectious Diseases, Singapore General Hospital, Outram Road, Singapore 169608. Candice.chan.y.y@singhealth.com.sg.
Yuen Yue Candice
YY
Chan
Ai Ling
AL
Tan
Ban Hock
BH
Tan
D000038:Abscess / Q000382:microbiology*; D000935:Antifungal Agents / Q000627:therapeutic use; D001203:Ascomycota; D017809:Fatal Outcome; D006801:Humans; D016867:Immunocompromised Host; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy*; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D003904:Mitosporic Fungi; D009181:Mycoses / Q000150:complications* / Q000188:drug therapy*; D009203:Myocardial Infarction / Q000150:complications; D011183:Postoperative Complications; D012846:Singapore; D066027:Transplant Recipients; D016896:Treatment Outcome
D000935:Antifungal Agents