Mucoperiosteal exostoses in the tympanic bulla of African lions (Panthera leo).
Mucoperiosteal exostoses (MpEs) of the tympanic bulla (TB), also referred as middle-ear otoliths, have been occasionally described in dogs and cats in association with clinical signs of otitis media or as an incidental finding, but they have not been recorded in other species. In this report, we describe the radiographic, gross, and histopathologic features of MpEs in 8 African lions (Panthera leo). All animals (5 males and 3 females) were adults that had been kept in captivity and had their skeletons conserved as part of an anatomic academic collection. A radiographic study revealed mineralized structures in the TB consistent with MpEs in 7 of the 16 examined TB; a computed tomography study identified MpEs in 12 of the 16 TB. Six TB from 4 lions were sectioned, and several MpEs were demineralized for histopathologic analysis. Grossly, MpEs appeared variable in number and shape. Some were globular structures that were loosely attached to the mucosal surface of the TB; others were isolated to coalescent bone spicules extending from the mucoperiosteum. Position was also variable, but MpEs frequently developed in the hypotympanum, especially on the ventromedial aspect of the TB wall. Microscopically, MpEs were composed of osteonal bone growing from the periosteum and not by dystrophic calcification of necrotic tissue debris, as is hypothesized in dogs.
Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, Spain.
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M
Novales
Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, Spain.
P J
PJ
Ginel
Department of Anatomy and Comparative Pathology, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, Spain.
A
A
Diz
Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, Spain.
B
B
Blanco
IUSA, University of Las Palmas de Gran Canaria, Las Palmas, Spain.
R
R
Zafra
Zoological Garden of Córdoba, Córdoba, Spain.
R
R
Guerra
Department of Anatomy and Comparative Pathology, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, Spain an1momoe@uco.es.
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E
Mozos
D000818:Animals; D004432:Ear, Middle / Q000473:pathology*; D005096:Exostoses / Q000473:pathology / Q000662:veterinary*; D005260:Female; D008045:Lions; D008297:Male; D014057:Tomography, X-Ray Computed / Q000662:veterinary
African lion; Panthera leo; computed tomography; middle ear; mucoperiosteal exostoses; pathology; tympanic bulla