Demineralized bone matrix, as a graft enhancer of auto-local bone in posterior lumbar interbody fusion.
METHODS
A case controlled study with prospective data collection.


OBJECTIVE
To evaluate the early influence and the final consequence of demineralized bone matrix (DBM) on auto-local bone as a graft enhancer in posterior lumbar interbody fusion (PLIF).


BACKGROUND
DBM is known as an osteoinductive material; however, it has not been clearly recognized to enhance auto-local bone with a small amount.


METHODS
Patients who had a PLIF were allocated into two groups. Group I (70 cases) used auto-local bone chips and group II (44 cases) used DBM as an additive to auto-local bone, 1 mL per a segment. Group selection was alternated. Early assessment was performed by computed tomography at 6 months and final assessment was done by simple radiography after 24 months at least. The degree of bone formation was assessed by 4 grade scale.


RESULTS
The subjects of both groups were homogenous and had similar Oswestry Disability Index at final assessment. The ratio of auto-local bone chips and DBM was 6:1. The degree of bone formation at 6 months after surgery was superior in group II. However, there was no significant difference between the two groups at the final assessment.


CONCLUSIONS
DBM was not recognized to enhance auto-local bone with small amount.
Department of Orthopedic Surgery, Seoul Sacred Heart General Hospital, Seoul, Korea.
Dong Ki
DK
Ahn
Department of Orthopedic Surgery, Seoul Sacred Heart General Hospital, Seoul, Korea.
Sang Ho
SH
Moon
Department of Orthopedic Surgery, Seoul Sacred Heart General Hospital, Seoul, Korea.
Tae Woo
TW
Kim
Department of Orthopedic Surgery, Seoul Sacred Heart General Hospital, Seoul, Korea.
Kyung Hwan
KH
Boo
Department of Orthopedic Surgery, Seoul Sacred Heart General Hospital, Seoul, Korea.
Sung Won
SW
Hong
Demineralized bone matrix; Graft enhancer; Posterior lumbar interbody fusion