Antibiotics in South Indian coastal sea and farmed prawns (Penaeus monodon).
Sulphonamides and chloramphenicol antibiotics were analysed by using liquid chromatography-tandem mass spectrometry (LC-MS/MS) in sea and farmed prawn (Penaeus monodon) samples obtained from the coastal region of southern India during 2011-2012. Average recoveries were 77-99% and precision was between 1% and 8%. The results revealed that in sea prawn samples neither of the two antibiotics was detected, but in farmed samples from coastal Andhra Pradesh some sulphonamides were detected in a concentration range greater than the maximum residual limit as set by Council Directive 2377/90 EC.
a Department of Pharmaceutical Analysis , Sir C R Reddy college of Pharmaceutical Sciences , Eluru , Andhra Pradesh , India.
Venkatesh
V
Palaniyappan
Arun Kumar
AK
Nagalingam
Hari Prasad
HP
Ranganathan
Krishnamoorthy Bharathi
KB
Kandhikuppam
Hari Prasath
HP
Kothandam
Soumya
S
Vasu
D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis*; D017756:Aquaculture; D002701:Chloramphenicol / Q000032:analysis; D002851:Chromatography, High Pressure Liquid; D004350:Drug Residues / Q000032:analysis*; D005062:European Union; D005506:Food Contamination; D005513:Food Inspection / Q000379:methods* / Q000592:standards; D019983:Guideline Adherence; D006291:Health Policy; D006293:Health Promotion; D006801:Humans; D007194:India; D019156:Indian Ocean; D057230:Limit of Detection; D033561:Penaeidae / Q000254:growth & development / Q000378:metabolism*; D015203:Reproducibility of Results; D012758:Shellfish / Q000032:analysis* / Q000592:standards; D013449:Sulfonamides / Q000032:analysis; D053719:Tandem Mass Spectrometry
D000900:Anti-Bacterial Agents; D013449:Sulfonamides; D002701:Chloramphenicol
LC-MS/MS; chloramphenicol; farmed; prawns; sea; sulphonamides