Incidence of bacteremia following bronchoscopy with argon plasma coagulation: a prospective study.
BACKGROUND
This evaluation was undertaken to determine the incidence of bacteremia and infectious complications associated with argon plasma coagulation (APC) procedures.


METHODS
Consecutive patients undergoing bronchoscopy with APC for treatment of endobronchial lesions were studied. Venesection was performed for blood cultures within 60 s of the APC procedure. APC catheter washings were cultured. Patients with positive blood cultures were reviewed immediately. All patients underwent clinical review 1 and 12 weeks after APC.


RESULTS
Forty-two patients underwent 44 APC procedures. Their mean age was 66 ± 12 years. One case (2.3 %) had bacteremia with Acinetobacter lwolfii. APC catheter washing culture was positive in 14 (31.8 %) procedures. No patient had clinical features suggesting infection and there were no complications. Phone review after 1 week revealed no complications. After 3 months, 8 (18 %) had died, all related to advanced lung malignancy and not to the APC procedure.


CONCLUSIONS
APC does not appear to increase the risk of bacteremia compared to airway insertion of the bronchoscope. Although contamination of the APC catheter with oropharyngeal commensal bacteria is common, clinically significant infection following the APC procedure is rare.
Pulmonary Department, Meir Medical Center, 59 Tchernichovsky St., 44281, Kfar Saba, Israel.
Alona
A
Matveychuk
Alexander
A
Guber
Olga
O
Talker
David
D
Shitrit
D000368:Aged; D057908:Argon Plasma Coagulation / Q000009:adverse effects* / Q000295:instrumentation; D016470:Bacteremia / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology; D020680:Bronchoscopes; D001999:Bronchoscopy / Q000009:adverse effects* / Q000295:instrumentation; D055499:Catheter-Related Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology; D057785:Catheters; D005260:Female; D006801:Humans; D015994:Incidence; D007557:Israel / Q000453:epidemiology; D008175:Lung Neoplasms / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009960:Oropharynx / Q000382:microbiology*; D010166:Palliative Care; D010865:Pilot Projects; D011446:Prospective Studies; D013997:Time Factors