Comparison of frequency of radial artery occlusion after 4Fr versus 6Fr transradial coronary intervention (from the Novel Angioplasty USIng Coronary Accessor Trial).
The frequency of radial artery occlusion was compared between patients receiving 4Fr versus 6Fr transradial coronary interventions (TRIs) in an open-label randomized trial (ClinicalTrials.gov identifier: NCT00815997). The primary outcome measure was radial artery occlusion on the day after TRI. The secondary outcome measures were the procedural success, major advanced cardiac events, access site-related complications, procedural times, fluoroscopy times, and contrast dye usage. A total of 160 patients were included. The procedure was successful in 79 of 80 patients (99%) in both groups. Whereas the 4Fr group showed no access site-related complications, the 6Fr developed 5 (6%), including 3 radial artery occlusions and 2 bleedings (1 radial artery perforation and 1 massive hematoma; p = 0.02). Although the radial artery occlusion rate was lower in the 4Fr versus the 6Fr groups, the difference was not significant (0% vs 4%, p = 0.08). The mean hemostasis time was significantly shorter in the 4Fr than in the 6Fr groups (237 ± 105 vs 320 ± 238 minutes, p = 0.007). In conclusion, these findings suggest that 4Fr TRI may become a less invasive alternative to 6Fr TRI in treating coronary artery diseases.
Nagasaki Harbor Medical Center, Nagasaki, Japan. Electronic address: stake@muse.ocn.ne.jp.
Satoshi
S
Takeshita
Tosei General Hospital, Seto, Japan.
Hiroshi
H
Asano
Kyoto Kujo Hospital, Kyoto, Japan.
Tetsuya
T
Hata
Yokohama City University Medical Center, Yokohama, Japan.
Kiyoshi
K
Hibi
Tokai University, Isehara, Japan.
Yuji
Y
Ikari
Fukuoka Heart Clinic, Fukuoka, Japan.
Yoshifumi
Y
Kan
Jichi Medical University, Utsunomiya, Japan.
Takaaki
T
Katsuki
Shin-Koga Hospital, Kurume, Japan.
Tomohiro
T
Kawasaki
Hyogo College of Medicine, Nishinomiya, Japan.
Motomaru
M
Masutani
Kumamoto Rosai Hospital, Yatsushiro, Japan.
Toshiyuki
T
Matsumura
Krishna Institute of Medical Sciences, Hyderabad, India.
Rajendra K
RK
Premchand
Global Hospitals, Hyderabad, India.
Surya P
SP
Rao
Kin-ikyo Central Hospital, Sapporo, Japan.
Takashi
T
Suzuki
Sakurakai Takahashi Hospital, Kobe, Japan.
Akihiko
A
Takahashi
Saiseikai Narashino Hospital, Narashino, Japan.
Ryuichi
R
Takeda
Shonan Atsugi Hospital, Atsugi, Japan.
Shinji
S
Tanaka
Sapporo Higashi Tokushukai Hospital, Sapporo, Japan.
Seiji
S
Yamazaki
Cheng-Hsin General Hospital, Taipei, Taiwan.
Wei-Hsian
WH
Yin
Aomori Prefectural Central Hospital, Aomori, Japan.
Fuminobu
F
Yoshimachi
Shonan Kamakura General Hospital, Kamakura, Japan.
Shigeru
S
Saito
D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects* / Q000379:methods; D001157:Arterial Occlusive Diseases / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology; D006328:Cardiac Catheterization / Q000009:adverse effects* / Q000379:methods; D057785:Catheters; D017023:Coronary Angiography / Q000379:methods; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D004867:Equipment Design; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007564:Japan; D008297:Male; D008875:Middle Aged; D017534:Radial Artery / Q000000981:diagnostic imaging / Q000503:physiopathology*; D012016:Reference Values; D018570:Risk Assessment; D015996:Survival Rate; D016896:Treatment Outcome