Using humans to make a human leishmaniasis vaccine.
The cellular immune response to peptide pools from conserved Leishmania antigens in leishmaniasis-immune individuals identified epitopes for a human DNA vaccine (Das et al., this issue).
Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA.
Shaden
S
Kamhawi
Fabiano
F
Oliveira
Jesus G
JG
Valenzuela
D000818:Animals; D018984:Epitopes, T-Lymphocyte / Q000276:immunology*; D005260:Female; D006801:Humans; D007896:Leishmaniasis / Q000276:immunology* / Q000517:prevention & control*; D019444:Vaccines, DNA / Q000276:immunology* / Q000627:therapeutic use*
D018984:Epitopes, T-Lymphocyte; D019444:Vaccines, DNA