[Fever, atrial fibrillation, and angina pectoris in a 58-year-old man].
Primary cardiac lymphoma (PCL) respresents a very rare type of cardiac tumour. This report illustrates a case of PCL in an immunocompetent 58-year-old man presenting with atrial fibrillation and febrile syndrome. Comprehensive imaging [computer tomography (CT), cardiac magnetic resonance imaging (cMRI), 3-dimensional transesophageal echocardiography (3D-TEE)] identified a large right atrial tumour, leading to pericardial effusion. Isolated cardiac involvement was confirmed by positron emission tomography (PET)-CT. A diffuse large B-cell lymphoma (DLBCL) was diagnosed based on the results of a TEE-guided biopsy. A normalized PET scan (PETAL study) indicated complete remission following R-CHOP 14 immunochemotherapy. Thus, an interdisciplinary and multimodal approach avoided unnecessary cardiac surgery.
Klinik für Kardiologie und Pulmonologie, Klinikum Passau, Innstr. 76, 94032, Passau, Deutschland, michael.groebner@klinikum-passau.de.
M
M
Groebner
T
T
Südhoff
M
M
Doering
M
M
Kirmayer
T
T
Nitsch
L
L
Prügl
W
W
Römer
H
H
Wolf
J
J
Tacke
P
P
Massoudy
T
T
Nüsse
D
D
Elsner
D000368:Aged; D000787:Angina Pectoris / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D058846:Antibodies, Monoclonal, Murine-Derived / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D001281:Atrial Fibrillation / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D003520:Cyclophosphamide / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004317:Doxorubicin / Q000008:administration & dosage; D005335:Fever of Unknown Origin / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control; D006338:Heart Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D008223:Lymphoma / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D008297:Male; D011241:Prednisone / Q000008:administration & dosage; D000069283:Rituximab; D016896:Treatment Outcome; D014750:Vincristine / Q000008:administration & dosage
D058846:Antibodies, Monoclonal, Murine-Derived; C571759:R-CHOP protocol; D000069283:Rituximab; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone