A preliminary study on atrial epicardial mapping signals based on Graph Theory.
In order to get a better understanding of atrial fibrillation, we introduced a method based on Graph Theory to interpret the relations of different parts of the atria. Atrial electrograms under sinus rhythm and atrial fibrillation were collected from eight living mongrel dogs with cholinergic AF model. These epicardial signals were acquired from 95 unipolar electrodes attached to the surface of the atria and four pulmonary veins. Then, we analyzed the electrode correlations using Graph Theory. The topology, the connectivity and the parameters of graphs during different rhythms were studied. Our results showed that the connectivity of graphs varied from sinus rhythm to atrial fibrillation and there were parameter gradients in various parts of the atria. The results provide spatial insight into the interaction between different parts of the atria and the method may have its potential for studying atrial fibrillation.
Department of Electronic Engineering, Fudan University, Shanghai 200433, China.
Liqian
L
Sun
Department of Electronic Engineering, Fudan University, Shanghai 200433, China. Electronic address: yangcw@fudan.edu.cn.
Cuiwei
C
Yang
Department of Electronic Engineering, Fudan University, Shanghai 200433, China.
Lin
L
Zhang
Department of Electronic Science and Engineering, Nanjing University, Nanjing 211102, China.
Ying
Y
Chen
Department of Cardiovascular Surgery, West China Hospital, Sichuan University, 37 Guoxue Road, Chengdu, Sichuan 610041, China.
Zhong
Z
Wu
Department of Thoracic and Cardiovascular Surgery, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China.
Jun
J
Shao
D000465:Algorithms; D000818:Animals; D001281:Atrial Fibrillation / Q000175:diagnosis* / Q000503:physiopathology*; D018780:Body Surface Potential Mapping / Q000379:methods*; D003198:Computer Simulation; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004285:Dogs; D006325:Heart Atria / Q000503:physiopathology; D006329:Heart Conduction System / Q000503:physiopathology*; D008955:Models, Cardiovascular; D009716:Numerical Analysis, Computer-Assisted; D010496:Pericardium / Q000503:physiopathology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
Atrial fibrillation; Epicardial mapping; Graph Theory