Thyroid stimulating hormone assay as the first line biochemical parameter to determine thyroid gland abnormalities.
Increased cellular catabolic activities observed in hyperthyroid state had been established. This is consequent to excessive hormones secreted by the thyroid gland during this condition. A total of 60 subjects comprising of 45 females mean age 43.02 +/- 1.90 (range 22-70 years) and 15 males mean age 50.40 +/- 3.59 (range 25-68) and 60 controls comprising of 45 females mean age 41.18 +/- 1.68 (range 22-68 years) and 15 males mean age 40.53 +/- 2.88 (range 25-65) were recruited for the study. The plasma level of T4, T3 and TSH were determined in both the experiment group and the controls. A significant increase (p < 0.05) in plasma T4, T3 and a significant decrease (p < 0.05) in plasma TSH were observed in the experiment group in comparison to the controls. Also, an inverse relationship was noted to exist between the plasma T4 and T3; and TSH in primary hyperthyroid state.
Wasiu Eniola
WE
Olooto
Adebambo Olufemi
AO
Adeleye
Adebayo Adetola
AA
Amballi
Ademola Oladipupo
AO
Mosuro
Taiwo Abayomi
TA
Banjo
D000328:Adult; D000368:Aged; D001774:Blood Chemical Analysis; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood* / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D013972:Thyrotropin / Q000097:blood*; D055815:Young Adult
D013972:Thyrotropin