Serum growth arrest-specific protein 6 levels are elevated in adult-onset Still's disease.
We investigated the growth arrest-specific protein 6 in adult-onset Still's disease. Serums were collected from 52 adult-onset Still's disease patients with follow-up samples of 21 patients. The growth arrest-specific protein 6 levels in adult-onset Still's disease were higher compared to those in the normal controls (25.37±7.71 vs. 19.86±5.01 ng/mL, p<0.001). However, growth arrest-specific protein 6 did not correlate with disease activity. Also, growth arrest-specific protein 6 was not decreased after activity was resolved in the follow-up. The growth arrest-specific protein 6 in adult-onset Still's disease patients were higher than the normal controls. However, growth arrest-specific protein 6 was not correlated with disease activity.
Department of Rheumatology, Ajou University School of Medicine, San 5, Wonchon-dong, Yeongtong-gu, Suwon, 443-721, South Korea.
Hyoun-Ah
HA
Kim
Jin-Young
JY
Nam
Ju-Yang
JY
Jung
Chang-Bum
CB
Bae
Jeong-Mi
JM
An
Ja-Young
JY
Jeon
Bong-Sik
BS
Kim
Chang-Hee
CH
Suh
D000328:Adult; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005786:Gene Expression Regulation; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D056910:Republic of Korea; D016706:Still's Disease, Adult-Onset / Q000097:blood*; D000099255:Growth Arrest-Specific Protein 6
D015415:Biomarkers; D036341:Intercellular Signaling Peptides and Proteins; D000099255:Growth Arrest-Specific Protein 6