Occurrence of ochratoxin A in wine and beer samples from China.
A total of 125 wine and beer samples, including 42 white, 63 red wine and 20 beer samples, originating from several areas of China were analyzed for ochratoxin A (OTA). An analytical method based on immunoaffinity column (IAC) for clean-up and high performance liquid chromatography with fluorescence detection (HPLC-FD) was used to determine OTA. Positive results were further confirmed by LC-MS-MS. OTA was detected in 22 (17.6%) samples at levels of 0.02-1.18 ng/ml, which were below the EU maximum limit. The mean OTA concentration in red wine was slightly higher than in white wine. This study showed that OTA occurs in wine and beer in China but at levels that pose no danger of significant human exposure to OTA from this source.
a Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College , 100193 Beijing , China.
Jianwei
J
Wu
Yinfeng
Y
Tan
Yuqi
Y
Wang
Rong
R
Xu
D053000:Analytic Sample Preparation Methods; D001515:Beer / Q000032:analysis* / Q000382:microbiology / Q000592:standards; D002273:Carcinogens / Q000032:analysis* / Q000737:chemistry; D002681:China; D002846:Chromatography, Affinity; D002851:Chromatography, High Pressure Liquid; D005062:European Union; D005285:Fermentation; D005506:Food Contamination; D005513:Food Inspection / Q000379:methods*; D019983:Guideline Adherence; D006291:Health Policy; D006293:Health Promotion; D006801:Humans; D009793:Ochratoxins / Q000032:analysis* / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D021241:Spectrometry, Mass, Electrospray Ionization; D053719:Tandem Mass Spectrometry; D013723:Teratogens / Q000032:analysis* / Q000737:chemistry; D014920:Wine / Q000032:analysis* / Q000382:microbiology / Q000592:standards
D002273:Carcinogens; D009793:Ochratoxins; D013723:Teratogens; C025589:ochratoxin A
beer; environmental contaminants; mycotoxins, ochratoxin A; wine