A confusing coincidence: neonatal hypoglycemic seizures and hyperekplexia.
Hyperekplexia is a rare, nonepileptic, genetic, or sporadic neurologic disorder characterized by startle responses to acoustic, optic, or tactile stimuli. Genetic defects in glycine receptors as well as encephalitis, tumors, inflammation, and disgenesis are among the etiologic causes of the disease. The main problem in hyperekplexia is the incomplete development of inhibitory mechanisms or exaggerated stimulation of excitatory mediators. Hyperekplexia is often confused with epileptic seizures. Here we present a case with hypoglycemic convulsions coexisting with hyperekplexia, causing diagnostic difficulty.
Department of Pediatrics, Division of Neonatology, Yuzuncu Yil University School of Medicine, 65200 Van, Turkey ; Hospital of the Yuzuncu Yil University, 65250 Van, Turkey.
Nihat
N
Demir
Department of Pediatrics, Division of Endocrinology, Yuzuncu Yil University School of Medicine, 65200 Van, Turkey.
Murat
M
Doğan
Department of Pediatrics, Division of Neurology, Ege University School of Medicine, İzmir, Turkey.
Sanem
S
Yılmaz
Department of Pediatrics, Division of Neonatology, Yuzuncu Yil University School of Medicine, 65200 Van, Turkey.
Erdal
E
Peker
Department of Pediatrics, Division of Endocrinology, Yuzuncu Yil University School of Medicine, 65200 Van, Turkey.
Keziban
K
Bulan
Department of Pediatrics, Division of Neonatology, Yuzuncu Yil University School of Medicine, 65200 Van, Turkey.
Oğuz
O
Tuncer