Leukemoid reaction, a rare manifestation of autoimmune hemolytic anemia in a case of small duct primary sclerosing cholangitis.
A 48 year old lady presented with jaundice and exertional breathlesness. Her laboratory reports showed anaemia, reticulocytosis, leucocytosis, elevated Lactate Dehydrogenase (LDH), alkaline phosphatase levels, hyperbillirubinemia and positive direct Coomb's test. After ruling out all the other causes of autoimmunity and hemolytic anemia, she was diagnosed as leukemoid reaction due to autoimmune hemolytic anemia with primary sclerosing cholangitis. Patient showed immediate improvement after corticosteroids.
Kaustubh D
KD
Salagre
Ravindra Nath
RN
Sahay
Anuja
A
Patil
Anuja
A
Pati
Amita
A
Joshi
Akash
A
Shukla
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D015209:Cholangitis, Sclerosing / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007955:Leukemoid Reaction / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D008875:Middle Aged
D000305:Adrenal Cortex Hormones