Metal-free aerobic oxidative C-N bond cleavage of tertiary amines for the synthesis of N-heterocycles with high atom efficiency.
An efficient metal-free aerobic oxidative C-N bond cleavage of tertiary amines has been developed to construct N-heterocycles using molecular oxygen as the sole oxidant with high atom efficiency, in which all of the three alkyl groups in tertiary amines can be utilized and transformed into N-heterocycles.
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410081, P. R. China. zhouyb@hnu.edu.cn sf_yin@hnu.edu.cn.
Xiuling
X
Chen
Tieqiao
T
Chen
Yongbo
Y
Zhou
Daoqing
D
Han
Li-Biao
LB
Han
Shuang-Feng
SF
Yin
D000332:Aerobiosis; D000588:Amines / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry*; D008670:Metals / Q000737:chemistry*; D010084:Oxidation-Reduction
D000588:Amines; D006571:Heterocyclic Compounds; D008670:Metals