A case of diffuse large B-cell lymphoma complicated by hemophagocytic syndrome.
BACKGROUND
Hemophagocytic syndrome (HPS) is a fatal disease and T-cell lymphoma is a common cause of this syndrome. The authors describe a rare case of diffuse large B-cell lymphoma (DLBCL) with HPS.


METHODS
Hematologic investigation, bone marrow aspirate and biopsy, cytogenetic analysis and lymph node biopsy were performed.


RESULTS
The patient obtained transient complete remission with rituximab and chemotherapy but relapsed soon within the observation period.


CONCLUSIONS
More aggressive therapy should be given in order to obtain a better therapeutic effect for the patients of DLBCL with HPS.
Xudong
X
Li
Yi
Y
He
Dongning
D
Wang
Yuan
Y
Hu
Wenwen
W
Wang
Renwei
R
Huang
D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000209:etiology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications*; D008297:Male; D008875:Middle Aged