Effect of Ramadan Fasting on Body Weight, (BP) and Biochemical Parameters in Middle Aged Hypertensive Subjects: An Observational Trial.
BACKGROUND
Ramadan fasting is a religious obligation which is practised by Muslim population all over the world. However, there is scarcity of scientific literature regarding its effects on health determinants in cardiovascular disturbances like hypertension.


OBJECTIVE
The present study was done to assess the (BP), body weight and serum cholesterol changes over the period of Ramadan fasting in patients with hypertension. Materails And Methods:This prospective observational trial was done on 15 hypertensive subjects who were in the age group of 35 to 65 years, who were determined to complete Ramadan fast. All subjects were on antihypertensive therapy. Outcome measures of (BP), body weight and serum cholesterol were assessed in all the subjects before and after Ramadan month.


RESULTS
Mean age of subjects was 44.6 ± 5.62 years. Systolic BP decreased from 148 ± 19.6 to 132.5 ± 17.9 mm of Hg. The decrease of 15.5 units (95% CI: 7.5 to 24.4) was statistically significant (p = 0.0009). Diastolic BP decreased from 90.4 ± 7.8 to 81.1 ± 6.3 mm of Hg. The decrease of 9.3 units (95% CI: 5.7 to 13) was statistically significant (p < 0.0001). There was statistically significant decrease in body weight from 66.6 ± 13 to 65.2 ± 12.7 kg (p < 0.0001). There was no significant difference in serum cholesterol from 187.3 ± 28.9 to 192.7 ± 31.3 mg% (p = 0.37).


CONCLUSIONS
Hypertensive patients with continuation of their medicines showed a decrease in blood pressure and reduction in body weight at the end of Ramadan fasting duration. However there was no change found in serum cholesterol levels.
Associate Professor, Department of Physiology, College of Medicine, Suleiman Al Rajhi Colleges , Bukayriah, Al Qassim, Saudi Arabia .
Salahuddin
S
M
Associate Professor, Department of Physiology, Indian Institute of Medical Science and Research Medical College , Warudi, Badnapur, Jalna, Maharashtra, India .
Sayed Ashfak
SA
Ah
Registrar, Department of Orthopaedics, MGM Medical College , Maharashtra, India .
Syed
S
Sr
Assistant Professor, Department of Physiology, Government Medical College , Aurangabad, Maharashtra, India .
Badaam
B
Km
Cardiovascular abnormality; Muslim fasting