An imported case of acute pulmonary coccidioidomycosis in an Italian traveller.
Coccidioidomycosis is a fungal infection caused by the Coccidioides species, which is endemic in the deserts of the southwestern region of the United States, northern Mexico, and in some areas of Central and South America. We describe a case of pulmonary coccidioidomycosis in a 49-year-old Italian man who came to our hospital with fever and joint and muscle pain 10 days after his return to Italy from Venezuela. Computer Tomography revealed multiple bilateral pulmonary nodules with mediastinal lymphadenopathy. Pulmonary coccidioidomycosis was diagnosed by a serological test, and fluconazole was immediately started. The patient improved within 2 weeks, with complete clinical recovery after 6 months of therapy. This case appears to be part of a large serologically unconfirmed outbreak. In order to provide early diagnosis and treatment, healthcare providers should be aware of coccidioidomycosis, even in travellers returning home from short trips to endemic areas.
L.Spallanzani National Institute for Infectious Diseases, I.R.C.C.S, Rome, Italy, angela.corpolongo@inmi.it.
A
A
Corpolongo
M L
ML
Giancola
P
P
Ghirga
A
A
Oliva
P
P
Mencarini
S
S
Pane
R
R
Bellagamba
C
C
Tommasi
A
A
Antinori
E
E
Nicastri
D061605:Administration, Intravenous; D000284:Administration, Oral; D000935:Antifungal Agents / Q000627:therapeutic use*; D003045:Coccidioides / Q000302:isolation & purification*; D003047:Coccidioidomycosis / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D003937:Diagnosis, Differential; D015725:Fluconazole / Q000627:therapeutic use*; D006801:Humans; D005779:Immunodiffusion; D007558:Italy; D008172:Lung Diseases, Fungal / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D014195:Travel; D016896:Treatment Outcome
D000935:Antifungal Agents; D015725:Fluconazole