Fatal nitrofurantoin lung.
Nitrofurantoin is a drug commonly used for urinary tract infections. It acts by damaging bacterial DNA. It is given in dose of 50-100 mg orally and is generally considered a safe drug but has occasionally been known to cause pulmonary toxicity which is usually reversible and only rarely fatal. We present a case of an elderly lady receiving nitrofurantoin for her urinary tract infection who developed sudden acute lung injury to which she finally succumbed within a few weeks.
Jai B
JB
Mullerpattan
Rucha S
RS
Dagaonkar
Hardik D
HD
Shah
Zarir F
ZF
Udwadia
D000368:Aged; D000892:Anti-Infective Agents, Urinary / Q000009:adverse effects*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000139:chemically induced* / Q000175:diagnosis*; D009582:Nitrofurantoin / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
D000892:Anti-Infective Agents, Urinary; D009582:Nitrofurantoin