Long-term survival outcome of laparoscopic staging surgery for endometrial cancer in Taiwanese experience.
OBJECTIVE
This study aims to evaluate the long-term safety and efficacy of laparoscopic staging surgery (LSS) for endometrial cancer in Taiwanese women.


METHODS
This is a longitudinal study of prospectively registered 105 patients who underwent LSS for endometrial cancer between June 1995 and June 2008.


RESULTS
The mean duration of surgery was 186.8 minutes, and the mean intraoperative blood loss was 220.38 mL. The median number of retrieved pelvic lymph nodes was 18. The intraoperative complication rate was 4.8%, including two cases of ureteral injury and one case each of bladder injury, bowel injury, and vascular injury. No patient required conversion to laparotomy. During the median follow-up of 55.3 months, six cases of recurrence (5.7%) and three tumor-related deaths (2.9%) were recorded. The 5-year disease-free survival and the overall survival were 93.39% and 98.05%, respectively.


CONCLUSIONS
The study revealed favorable perioperative outcomes and better long-term survival than reported in the Taiwan Cancer Registry, and similar good surgical results to those reported in the Western studies. Therefore, LSS by experienced surgeons for endometrial cancer is a feasible and efficacious alternative to laparotomy.
Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou, and Chang Gung University, Tao-Yuan, Taiwan.
Chyi-Long
CL
Lee
Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou, and Chang Gung University, Tao-Yuan, Taiwan.
Kuan-Gen
KG
Huang
Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou, and Chang Gung University, Tao-Yuan, Taiwan.
Pei-Ju
PJ
Wu
Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou, and Chang Gung University, Tao-Yuan, Taiwan.
Pei-Shan
PS
Lee
Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou, and Chang Gung University, Tao-Yuan, Taiwan; Institute of Clinical Medical Sciences, Chang Gung University School of Medicine, Tao-Yuan, Taiwan. Electronic address: yen2158@gmail.com.
Chih-Feng
CF
Yen
D001918:Brachytherapy; D018269:Carcinoma, Endometrioid / Q000401:mortality / Q000473:pathology / Q000628:therapy; D059248:Chemoradiotherapy; D018572:Disease-Free Survival; D016889:Endometrial Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007431:Intraoperative Complications / Q000401:mortality; D053208:Kaplan-Meier Estimate; D010535:Laparoscopy / Q000009:adverse effects / Q000401:mortality*; D008137:Longitudinal Studies; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality*; D009367:Neoplasm Staging; D061646:Operative Time; D012042:Registries / Q000706:statistics & numerical data; D013624:Taiwan
endometrial cancer; laparoscopy; staging surgery; survival