Diet and psoriasis, part II: celiac disease and role of a gluten-free diet.
Patients with psoriasis have been shown to have a higher prevalence of other autoimmune diseases including celiac disease, a condition marked by sensitivity to dietary gluten. A number of studies suggest that psoriasis and celiac disease share common genetic and inflammatory pathways. Here we review the epidemiologic association between psoriasis and celiac disease and perform a meta-analysis to determine whether patients with psoriasis more frequently harbor serologic markers of celiac disease. We also examine whether a gluten-free diet can improve psoriatic skin disease.
Department of Dermatology, University of California, San Francisco, California; Rush Medical College, Rush University Medical Center, Chicago, Illinois.
Bhavnit K
BK
Bhatia
Department of Dermatology, University of California, San Francisco, California; University of Utah School of Medicine, Salt Lake City, Utah.
Jillian W
JW
Millsop
Department of Dermatology, University of California, San Francisco, California; University of California, Irvine, School of Medicine, Irvine, California.
Maya
M
Debbaneh
Department of Dermatology, University of California, San Francisco, California.
John
J
Koo
Department of Dermatology, University of California, San Francisco, California.
Eleni
E
Linos
Department of Dermatology, University of California, San Francisco, California. Electronic address: liaowi@derm.ucsf.edu.
Wilson
W
Liao
D015415:Biomarkers / Q000097:blood; D002446:Celiac Disease / Q000178:diet therapy* / Q000453:epidemiology* / Q000276:immunology; D055050:Diet, Gluten-Free; D019204:GTP-Binding Proteins; D005903:Gliadin / Q000276:immunology; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood*; D000091345:Protein Glutamine gamma Glutamyltransferase 2; D011565:Psoriasis / Q000178:diet therapy* / Q000453:epidemiology* / Q000276:immunology; D012720:Severity of Illness Index; D011503:Transglutaminases / Q000276:immunology
D015415:Biomarkers; D007070:Immunoglobulin A; D005903:Gliadin; D000091345:Protein Glutamine gamma Glutamyltransferase 2; D011503:Transglutaminases; D019204:GTP-Binding Proteins
antigliadin; celiac disease; celiac sprue; diet; gluten-free; nutrition; psoriasis