The surgical management of Treacher Collins syndrome.
Treacher Collins syndrome (TCS), mandibulofacial dysostosis, or Franceschetti-Zwahlen-Klein syndrome, is a rare genetic disorder characterised by dysgenesis of the hard and soft tissues of the first and second branchial arches. Early operations focus on maintaining the airway, protecting the eyes, and supporting auditory neurological development. Later operations include staged reconstruction of the mouth, face, and external ear. Bimaxillary surgery can improve the maxillomandibular facial projection, but correction of malar, orbital rim, and temporal defects may be more difficult. We present a clinical review of the syndrome with a chronological approach to the operations.
Southwest Cleft Service and Oral & Maxillofacial Surgery Department, North Bristol NHS Trust, Bristol, United Kingdom. Electronic address: alicobb@yahoo.com.
Alistair R M
AR
Cobb
Craniofacial Service, Great Ormond Street Hospital, United Kingdom.
Ben
B
Green
Orthodontic Department, Great Ormond Street Hospital, London, United Kingdom.
Daljit
D
Gill
Maxillofacial Surgery Department, Great Ormond Street Hospital, London, United Kingdom.
Peter
P
Ayliffe
Adult Craniofacial Surgery Department, University College London Hospitals, United Kingdom.
Timothy W
TW
Lloyd
Plastic Surgery Department, Great Ormond Street Hospital, London, United Kingdom.
Neil
N
Bulstrode
Craniofacial Service, Great Ormond Street Hospital, United Kingdom.
David J
DJ
Dunaway
D000367:Age Factors; D005145:Face / Q000601:surgery; D005147:Facial Bones / Q000601:surgery; D006801:Humans; D008342:Mandibulofacial Dysostosis / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods
Franceschetti–Zwahlen–Klein syndrome; Mandibulofacial dysostosis; Treacher Collins syndrome