Chemotherapy-Induced Nausea and Vomiting.
Despite treatment advances, nausea and vomiting, especially anticipatory nausea and vomiting, delayed nausea and vomiting and nausea alone, are still the most common, expected and feared side effects among patients receiving chemotherapy. Of the 70 to 80% of cancer patients who experience chemotherapy-induced nausea and vomiting many will delay or refuse future chemotherapy treatments and contemplate stopping all treatments because of fear of further nausea and vomiting. The purpose of this chapter is to provide an overview of the patho-psychophysiology of CINV, the recommended guidelines for standard treatment, and highlight newer targeted treatment approaches.
University of Rochester School of Medicine and Dentistry, James P. Wilmot Cancer Center, Box 704, 601 Elmwood Avenue, Rochester, NY 14642.
Karen M
KM
Mustian
University of Rochester School of Medicine and Dentistry, James P. Wilmot Cancer Center, Box 704, 601 Elmwood Avenue, Rochester, NY 14642.
Tom V
TV
Darling
University of Rochester School of Medicine and Dentistry, James P. Wilmot Cancer Center, Box 704, 601 Elmwood Avenue, Rochester, NY 14642.
Michelle C
MC
Janelsins
University of Rochester School of Medicine and Dentistry, James P. Wilmot Cancer Center, Box 704, 601 Elmwood Avenue, Rochester, NY 14642.
Pascal
P
Jean-Pierre
University of Rochester School of Medicine and Dentistry, James P. Wilmot Cancer Center, Box 704, 601 Elmwood Avenue, Rochester, NY 14642.
Joseph A
JA
Roscoe
University of Rochester School of Medicine and Dentistry, James P. Wilmot Cancer Center, Box 704, 601 Elmwood Avenue, Rochester, NY 14642.
Gary R
GR
Morrow