Invasive pneumococcal infection despite 7-valent conjugated vaccine.
Despite good cover with 7-valent vaccination, invasive pneumococcal infections may still be misdiagnosed and may lead to lifethreatening situations or death in young children. New serotypes are emerging and, therefore, clinicians must keep a high level of suspicion in young children regardless of their vaccination status. We report three cases of invasive pneumococcal infection due to new serotypes not covered by the 7-valent conjugated vaccine, two of which led children to death.
Department of Pediatrics, University Hospital of Lausanne (CHUV) , Switzerland.
Sebastien
S
Joye
Department of Pediatrics, University Hospital of Lausanne (CHUV) , Switzerland.
Anja
A
Gao
Department of Pediatrics, University Hospital of Lausanne (CHUV) , Switzerland.
Simon
S
Kayemba-Kay's
Pediatric Intensive Care Unit, University Hospital of Lausanne (CHUV) , Switzerland.
Jacques
J
Cotting
Pediatric Intensive Care Unit, University Hospital of Lausanne (CHUV) , Switzerland.
Marie-Hélène
MH
Perez
7-valent conjugated vaccine; Streptococcus Pneumoniae; meningitis.; sepsis