A new steroid with long cross-conjugation structure from the marine-derived fungus Aspergillus aculeatus.
A new steroid with a long cross-conjugation structure, 15a-hydroxy-(22E, 24R)-ergosta-3, 5, 8 (14), 22-tetraen-7-one (1), was isolated from the marine-derived fungus Aspergillus aculeatus. Its structure was established by the extensive spectroscopic analyses, and its cytotoxicities against P388, HL-60, and PC-3 cell lines were measured in vitro.
Yu
Y
Wang
Zhan-Lin
ZL
Li
Tao
T
Liu
Li
L
Tian
Yue-Hu
YH
Pei
Hui-Ming
HM
Hua
D000818:Animals; D001230:Aspergillus / Q000737:chemistry*; D045744:Cell Line, Tumor / Q000187:drug effects; D002783:Cholestenones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018922:HL-60 Cells / Q000187:drug effects; D006801:Humans; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D012623:Seawater / Q000382:microbiology
C000591506:15alpha-hydroxy-(22E,24R)-ergosta-3,5,8(14),22-tetraen-7-one; D002783:Cholestenones