Infective endocarditis associated with mitral valve prolapse in a patient with Klinefelter syndrome.
We herein report a case of infective endocarditis associated with mitral valve prolapse (MVP) in a 34-year-old man with Klinefelter syndrome. The patient was admitted with a fever and headache that had persisted for three weeks. Repeated blood cultures showed growth of Streptococcus oralis. Echocardiography demonstrated severe mitral regurgitation with a large vegetation attached to the prolapsed anterior leaflet. Surgical plasty of the mitral valve was performed because the vegetation measured over 10 mm in diameter and there was a risk of recurrence of embolic complications. This case demonstrates the link between MVP and Klinefelter syndrome and highlights the importance of performing cardiovascular screening and preventing endocarditis.
Department of Cardiovascular Medicine, Shinshu University School of Medicine, Japan.
Yasushi
Y
Ueki
Atsushi
A
Izawa
Souichiro
S
Ebisawa
Hirohiko
H
Motoki
Yusuke
Y
Miyashita
Takeshi
T
Tomita
Jun
J
Koyama
Tamaki
T
Takano
Jun
J
Amano
Uichi
U
Ikeda
D000328:Adult; D017548:Echocardiography, Transesophageal; D004697:Endocarditis, Bacterial / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology; D006801:Humans; D007713:Klinefelter Syndrome / Q000150:complications* / Q000235:genetics; D008297:Male; D008943:Mitral Valve / Q000000981:diagnostic imaging; D008945:Mitral Valve Prolapse / Q000175:diagnosis / Q000209:etiology*; D013290:Streptococcal Infections / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology; D019533:Streptococcus oralis / Q000302:isolation & purification