Workers exposed to urban stressors and the effects on antidiuretic hormone secretion.
BACKGROUND
The aim of this study was to evaluate whether urban pollutants can affect plasma levels of antidiuretic hormone (ADH) in outdoor workers.


METHODS
We selected 208 subjects, 104 exposed to urban stressors and 104 non exposed to urban stressors. We divided these workers in 3 groups: Group 1 (non-smokers and non-drinkers), Group 2 (smokers and not drinkers) and Group 3 (drinkers and not smokers). The means and standard deviations of ADH were calculated, and a Student's t-test was used to compare means. The data were considered significant at p ≤ 0.05.


RESULTS
The outdoor workers in Group 1 had significantly reduced plasma levels of ADH. In contrast, the outdoor workers in Groups 2 and 3 had increased plasma levels of ADH. These results were consistent in both men and women.


CONCLUSIONS
The results suggest that urban pollutants may influence the secretion of ADH.
Department of Anatomy, Histology, Medical-Legal and Orthopedics, Unit of Occupational Medicine, "Sapienza" University of Rome, Rome, Italy.
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Caciari
Department of Anatomy, Histology, Medical-Legal and Orthopedics, Unit of Occupational Medicine, "Sapienza" University of Rome, Rome, Italy.
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Rosati
Department of Anatomy, Histology, Medical-Legal and Orthopedics, Unit of Occupational Medicine, "Sapienza" University of Rome, Rome, Italy.
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Sacco
Department of Anatomy, Histology, Medical-Legal and Orthopedics, Unit of Occupational Medicine, "Sapienza" University of Rome, Rome, Italy.
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Casale
Department of Anatomy, Histology, Medical-Legal and Orthopedics, Unit of Occupational Medicine, "Sapienza" University of Rome, Rome, Italy.
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Pimpinella
Department of Anatomy, Histology, Medical-Legal and Orthopedics, Unit of Occupational Medicine, "Sapienza" University of Rome, Rome, Italy.
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Bonomi
Department of Anatomy, Histology, Medical-Legal and Orthopedics, Unit of Occupational Medicine, "Sapienza" University of Rome, Rome, Italy.
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De Sio
Department of Anatomy, Histology, Medical-Legal and Orthopedics, Unit of Occupational Medicine, "Sapienza" University of Rome, Rome, Italy.
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Giubilati
Department of Anatomy, Histology, Medical-Legal and Orthopedics, Unit of Occupational Medicine, "Sapienza" University of Rome, Rome, Italy.
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Montuori
Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
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Weiderpass
Department of Anatomy, Histology, Medical-Legal and Orthopedics, Unit of Occupational Medicine, "Sapienza" University of Rome, Rome, Italy.
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Cancanelli
Department of Neurology and Psychiatry, "Sapienza" University of Rome, Rome, Italy.
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Tomei
Department of Anatomy, Histology, Medical-Legal and Orthopedics, Unit of Occupational Medicine, "Sapienza" University of Rome, Rome, Italy.
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Tomei
Department of Anatomy, Histology, Medical-Legal and Orthopedics, Unit of Occupational Medicine, "Sapienza" University of Rome, Rome, Italy.
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Sancini
D000328:Adult; D000393:Air Pollutants / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D016495:Police; D012384:Rome; D014504:Urban Health; D014667:Vasopressins / Q000378:metabolism*
D000393:Air Pollutants; D014667:Vasopressins