Single-institution outcomes in the first year of pancreas transplantation from brain-dead donors.
BACKGROUND
Under a revision to the law in 2010, the number of pancreas transplantations from brain-dead donors has been increasing in Japan. We started a new Pancreatic Transplant Program at Fujita Health University Hospital in September 2012.


METHODS
A total of 11 cases of pancreas transplantation from brain-dead donors performed at Fujita Health University Hospital were analyzed in terms of the background characteristics of the donors and recipients and the outcomes.


RESULTS
The mean age of the recipients was 45.2 years, and all recipients had a long-term history of diabetes (mean: 32.5 years). In the simultaneous pancreas and kidney transplantation (SPK) cases, the patients also had a long history of hemodialysis (mean: 8.0 years). Although the average donor age was 42.5 years, 90% of the donors were marginal donors, defined according to the following factors: (1) >45 years old, (2) death from cardiovascular disease, (3) episodes of cardiac arrest, (4) use of high doses of catecholamines. The pancreatic graft survival rate was 100%, although 1 patient required a small amount of insulin to maintain euglycemia. In addition, the kidney graft survival rate was also 100% in the SPK cases.


CONCLUSIONS
The new Pancreatic Transplant Program at Fujita Health University has provided excellent outcomes for type 1 diabetic patients.
Department of Organ Transplant Surgery, Fujita Health University, School of Medicine, Aichi, Japan. Electronic address: i-taihei@fujita-hu.ac.jp.
T
T
Ito
Department of Organ Transplant Surgery, Fujita Health University, School of Medicine, Aichi, Japan.
T
T
Kenmochi
Division of Endocrinology and Metabolism, Fujita Health University, School of Medicine, Aichi, Japan.
A
A
Suzuki
Department of Surgery, National Hospital Organization, Chiba East Hospital, Chiba, Japan.
M
M
Maruyama
Department of Urology, Fujita Health University, School of Medicine, Aichi, Japan.
M
M
Kusaka
Department of Urology, Fujita Health University, School of Medicine, Aichi, Japan.
H
H
Sasaki
Department of Surgery, National Hospital Organization, Chiba East Hospital, Chiba, Japan.
T
T
Asano
Department of Frontier Surgery, Chiba University, Graduate School of Medicine, Chiba, Japan.
H
H
Matsubara
Department of Urology, Fujita Health University, School of Medicine, Aichi, Japan.
K
K
Hoshinaga
D000328:Adult; D000368:Aged; D001926:Brain Death; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016035:Pancreas Transplantation; D014019:Tissue Donors; D016896:Treatment Outcome