Benign Hepatic Mesenchymal Hamartoma (HMH) - A Case Report.
A one-year-old male child presented with progressive enlargement of abdomen and loss of appetite which he had suffered from, since 4 months. Physical examination showed a palpable mass in right hypochondrium. Ultrasonography and MRI showed a solid mass arising from right lobe of liver. The resected mass was well encapsulated, yellowish white in colour and it measured 20 x 18 x 17cm. Cut surface showed a Nutmeg like appearance. Histology showed a well-defined, fibrous capsule with numerous ducts which were lined by flat to low cuboidal epithelium and which were surrounded by concentric layers of fibrous tissue which showed myxoid changes at places. Intervening area showed normal appearing hepatocytes with clear cell changes, dilated congested sinusoids, along with extramedullary haematopoiesis. Based on distinctive morphological features, a histological diagnosis of Benign Hepatic Mesenchymal Hamartoma of liver was made. IHC was not done, as no specific marker has been described for making a differential diagnosis. Benign Hepatic Mesenchymal Hamrtoma (HMH) of liver is an extremely rare tumour of childhood and therefore, the case was considered worth documentation.
Junior Resident, Department of Pathology, Motilal Nehru Medical College , Allahabad, Uttar Pradesh, India .
Shaileshkumar Radheshyam
SR
Patel
Head and Professor, Department of Pathology, Motilal Nehru Medical College , Allahabad, Uttar Pradesh, India .
Vatsala
V
Misra
Assistant Professor, Department of Pathology, Motilal Nehru Medical College , Allahabad, Uttar Pradesh, India .
Kachnar
K
Verma
Junior Resident, Department of Pathology, Motilal Nehru Medical College , Allahabad, Uttar Pradesh, India .
Pooja
P
Gupta
Lecturer, Department of Pathology, Motilal Nehru Medical College , Allahabad, Uttar Pradesh, India .
Vishal
V
Dhingra
Bile duct; Extramedullary hematopoiesis; Liver; Mesenchymal hamartoma; Paediatric tumour