Embryo selection using metabolomics.
Faced with an increasing demand to select one embryo to transfer back to patients, a number of techniques are being developed to assist in discriminating differences within the cohort of a patient's embryos. A new and emerging technology which allows us to measure the profile of different metabolites in embryo culture media and formulate a viability score correlated to implantation potential is metabolomics.
Boston IVF, 130 2nd Avenue, Waltham, MA, 02451, USA, denny.sakkas@yale.edu.
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Sakkas
D001755:Blastocyst / Q000378:metabolism; D003470:Culture Media / Q000378:metabolism; D046149:Embryo Culture Techniques / Q000379:methods; D010064:Embryo Implantation / Q000235:genetics; D004624:Embryo Transfer / Q000379:methods*; D004622:Embryo, Mammalian / Q000378:metabolism*; D005307:Fertilization in Vitro / Q000379:methods; D006801:Humans; D055432:Metabolomics / Q000379:methods*; D008967:Molecular Biology / Q000379:methods
D003470:Culture Media