Circumscribed choroidal hemangioma associated with choroidal neovascularization in a HIV-infected case: photodynamic therapy and intravitreous ranibizumab.
Circumscribed choroidal hemangioma (CCH) is rarely associated with choroidal neovascularization (CNV), especially in HIV-infected patients. And the therapy is still controversial. In this study, we discussed the mechanism, clinical feature and treatment of such lesions, based on multi-modality imaging evidences. Photodynamic therapy (PDT) might aggravate CNV as a side effect, and we concluded that intravitreal ranibizumab could be suggested as an effective therapy.
Department of Ophthalmology, First Hospital of China Medical University, Shenyang, People's Republic of China.
Rui
R
Hua
Department of Ophthalmology, First Hospital of China Medical University, Shenyang, People's Republic of China.
Ning
N
Zhao
Department of Ophthalmology, First Hospital of China Medical University, Shenyang, People's Republic of China.
Yuedong
Y
Hu
Georgetown University School of Medicine, Washington, DC, USA.
Christiana Meng
CM
Zhang
Department of Ophthalmology, First Hospital of China Medical University, Shenyang, People's Republic of China. Electronic address: LeiChen51@126.com.
Lei
L
Chen
D020533:Angiogenesis Inhibitors / Q000008:administration & dosage; D061067:Antibodies, Monoclonal, Humanized / Q000008:administration & dosage*; D000970:Antineoplastic Agents / Q000008:administration & dosage; D002830:Choroid Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D020256:Choroidal Neovascularization / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D004359:Drug Therapy, Combination / Q000379:methods; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D006391:Hemangioma / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D058449:Intravitreal Injections; D008875:Middle Aged; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000008:administration & dosage; D000069579:Ranibizumab; D016896:Treatment Outcome
D020533:Angiogenesis Inhibitors; D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents; D017319:Photosensitizing Agents; D000069579:Ranibizumab
Choroidal neovascularization; Circumscribed choroidal hemangioma; Enhanced depth imaging optical coherence tomography; HIV; Photodynamic therapy