Highly efficient gold-catalyzed synthesis of dibenzocycloheptatrienes.
Dibenzocycloheptatrienes are obtained by a gold-catalyzed 7-exo-dig hydroarylation protocol in a highly efficient manner. The gold-catalyzed reaction usually gives the products in high yields and excellent selectivity. This procedure provides an easy and efficient access to dibenzocycloheptanoids, which are an interesting and unique class of natural products. This was underlined by the first total synthesis of reticuol.
Organisch-Chemisches Institut, Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg (Germany).
Daniel
D
Pflästerer
Eva
E
Rettenmeier
Severin
S
Schneider
Edgar
E
de Las Heras Ruiz
Matthias
M
Rudolph
A Stephen K
AS
Hashmi
dibenzocycloheptanoids; gold; hydroarylation; natural products; total synthesis