GenCLiP 2.0: a web server for functional clustering of genes and construction of molecular networks based on free terms.
Identifying biological functions and molecular networks in a gene list and how the genes may relate to various topics is of considerable value to biomedical researchers. Here, we present a web-based text-mining server, GenCLiP 2.0, which can analyze human genes with enriched keywords and molecular interactions. Compared with other similar tools, GenCLiP 2.0 offers two unique features: (i) analysis of gene functions with free terms (i.e. any terms in the literature) generated by literature mining or provided by the user and (ii) accurate identification and integration of comprehensive molecular interactions from Medline abstracts, to construct molecular networks and subnetworks related to the free terms.


METHODS
http://ci.smu.edu.cn.


BACKGROUND
Supplementary data are available at Bioinformatics online.
Cancer Institute, Key Laboratory of Zebrafish Modeling and Drug Screening for Human Diseases of Guangdong Higher Education Institutes, Department of Cell Biology, Southern Medical University, Guangzhou 510515, Guangzhou Biotechnology Center, Guangzhou, 510630, School of Basic Medical Sciences, Network Center and Department of Plastic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Jia-Hong
JH
Wang
Cancer Institute, Key Laboratory of Zebrafish Modeling and Drug Screening for Human Diseases of Guangdong Higher Education Institutes, Department of Cell Biology, Southern Medical University, Guangzhou 510515, Guangzhou Biotechnology Center, Guangzhou, 510630, School of Basic Medical Sciences, Network Center and Department of Plastic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Ling-Feng
LF
Zhao
Cancer Institute, Key Laboratory of Zebrafish Modeling and Drug Screening for Human Diseases of Guangdong Higher Education Institutes, Department of Cell Biology, Southern Medical University, Guangzhou 510515, Guangzhou Biotechnology Center, Guangzhou, 510630, School of Basic Medical Sciences, Network Center and Department of Plastic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Pei
P
Lin
Cancer Institute, Key Laboratory of Zebrafish Modeling and Drug Screening for Human Diseases of Guangdong Higher Education Institutes, Department of Cell Biology, Southern Medical University, Guangzhou 510515, Guangzhou Biotechnology Center, Guangzhou, 510630, School of Basic Medical Sciences, Network Center and Department of Plastic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Xiao-Rong
XR
Su
Cancer Institute, Key Laboratory of Zebrafish Modeling and Drug Screening for Human Diseases of Guangdong Higher Education Institutes, Department of Cell Biology, Southern Medical University, Guangzhou 510515, Guangzhou Biotechnology Center, Guangzhou, 510630, School of Basic Medical Sciences, Network Center and Department of Plastic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Shi-Jun
SJ
Chen
Cancer Institute, Key Laboratory of Zebrafish Modeling and Drug Screening for Human Diseases of Guangdong Higher Education Institutes, Department of Cell Biology, Southern Medical University, Guangzhou 510515, Guangzhou Biotechnology Center, Guangzhou, 510630, School of Basic Medical Sciences, Network Center and Department of Plastic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Li-Qiang
LQ
Huang
Cancer Institute, Key Laboratory of Zebrafish Modeling and Drug Screening for Human Diseases of Guangdong Higher Education Institutes, Department of Cell Biology, Southern Medical University, Guangzhou 510515, Guangzhou Biotechnology Center, Guangzhou, 510630, School of Basic Medical Sciences, Network Center and Department of Plastic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Hua-Feng
HF
Wang
Cancer Institute, Key Laboratory of Zebrafish Modeling and Drug Screening for Human Diseases of Guangdong Higher Education Institutes, Department of Cell Biology, Southern Medical University, Guangzhou 510515, Guangzhou Biotechnology Center, Guangzhou, 510630, School of Basic Medical Sciences, Network Center and Department of Plastic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Hai
H
Zhang
Cancer Institute, Key Laboratory of Zebrafish Modeling and Drug Screening for Human Diseases of Guangdong Higher Education Institutes, Department of Cell Biology, Southern Medical University, Guangzhou 510515, Guangzhou Biotechnology Center, Guangzhou, 510630, School of Basic Medical Sciences, Network Center and Department of Plastic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Zhen-Fu
ZF
Hu
Cancer Institute, Key Laboratory of Zebrafish Modeling and Drug Screening for Human Diseases of Guangdong Higher Education Institutes, Department of Cell Biology, Southern Medical University, Guangzhou 510515, Guangzhou Biotechnology Center, Guangzhou, 510630, School of Basic Medical Sciences, Network Center and Department of Plastic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Kai-Tai
KT
Yao
Cancer Institute, Key Laboratory of Zebrafish Modeling and Drug Screening for Human Diseases of Guangdong Higher Education Institutes, Department of Cell Biology, Southern Medical University, Guangzhou 510515, Guangzhou Biotechnology Center, Guangzhou, 510630, School of Basic Medical Sciences, Network Center and Department of Plastic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Zhong-Xi
ZX
Huang
D016000:Cluster Analysis; D057225:Data Mining / Q000379:methods*; D053263:Gene Regulatory Networks; D005796:Genes; D006801:Humans; D020407:Internet; D016239:MEDLINE; D012984:Software