Cancer pain and current theory for pain control.
This article discusses current trends in managing cancer pain, with specific regard to opioid transmission, descending pathway inhabitation, and ways to facilitate the endogenous antinociceptive chemicals in the human body. Various techniques for opioid and nonopioid control of potential pain situations of patients with cancer are discussed. The benefits of using pharmacogenetics to assess the appropriate medications are addressed. Finally, specific treatment of abdominal cancer pain using radiofrequency lesioning is discussed.
The Kahan Center for Pain Management, 2002 Medical Parkway, Suite 150, Annapolis, MD 21401, USA. Electronic address: bkahan@thekahancenter.com.
Brian
B
Kahan
D000701:Analgesics, Opioid / Q000627:therapeutic use*; D002188:Cannabis; D005260:Female; D006801:Humans; D007278:Injections, Spinal; D008297:Male; D009369:Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D059408:Pain Management / Q000379:methods*; D010147:Pain Measurement; D010148:Intractable Pain / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy*; D011379:Prognosis; D018570:Risk Assessment; D012720:Severity of Illness Index; D050781:Transcranial Magnetic Stimulation / Q000379:methods; D016896:Treatment Outcome
D000701:Analgesics, Opioid
Cancer pain; NMDA antagonists; Opioid therapy; Splanchnic nerve blocks opioid pharmacogenetic testing