[Epidemiology of bone and joint disease - the present and future - . Genetic epidemiology on osteoarthritis].
Although a large number of studies have been made to identify genetic loci associated with osteoarthritis (OA), there are only a few that have been reported to be associated with OA in many regions and countries. One of the reasons for the lack of success may be small effect sizes. A sufficiently large sample size is required for the genetic epidemiology on OA to elucidate genetic influence regarding the occurrence and progression.
Department of Clinical Motor System Medicine, Graduate School of Medicine, University of Tokyo, Japan.
Toru
T
Akune
D020022:Genetic Predisposition to Disease / Q000235:genetics; D055428:Growth Differentiation Factor 5 / Q000235:genetics; D006801:Humans; D017720:Molecular Epidemiology / Q000379:methods; D010003:Osteoarthritis / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics*; D017410:Practice Guidelines as Topic; D012307:Risk Factors
C525893:GDF5 protein, human; D055428:Growth Differentiation Factor 5