Multimodal evaluation of 2-D and 3-D ultrasound, computed tomography and magnetic resonance imaging in measurements of the thyroid volume using universally applicable cross-sectional imaging software: a phantom study.
A precise estimate of thyroid volume is necessary for making adequate therapeutic decisions and planning, as well as for monitoring therapy response. The goal of this study was to compare the precision of different volumetry methods. Thyroid-shaped phantoms were subjected to volumetry via 2-D and 3-D ultrasonography (US), computed tomography (CT) and magnetic resonance imaging (MRI). The 3-D US scans were performed using sensor navigation and mechanical sweeping methods. Volumetry calculation ensued with the conventional ellipsoid model and the manual tracing method. The study confirmed the superiority of manual tracing with CT and MRI volumetry of the thyroid, but extended this knowledge also to the superiority of the 3-D US method, regardless of whether sensor navigation or mechanical sweeping is used. A novel aspect was successful use of the same universally applicable cross-imaging software for all modalities.
Clinic of Nuclear Medicine, Jena University Hospital, Jena, Germany. Electronic address: martin.freesmeyer@med.uni-jena.de.
Martin
M
Freesmeyer
Clinic of Nuclear Medicine, Jena University Hospital, Jena, Germany.
Steffen
S
Wiegand
Clinic of Nuclear Medicine, Jena University Hospital, Jena, Germany.
Jan-Henning
JH
Schierz
Clinic of Nuclear Medicine, Jena University Hospital, Jena, Germany.
Thomas
T
Winkens
Clinic of Nuclear Medicine, Jena University Hospital, Jena, Germany.
Katharina
K
Licht
D000465:Algorithms; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods; D064847:Multimodal Imaging / Q000295:instrumentation* / Q000379:methods*; D009929:Organ Size / Q000502:physiology; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013961:Thyroid Gland / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods; D014463:Ultrasonography / Q000295:instrumentation / Q000379:methods
Computed tomography; Magnetic resonance imaging; Three-dimensional; Thyroid; Thyroid volume; Ultrasonography; Volumetry