Response.
Affiliations of authors: Institute of Cancer and Genetics (CGS, HW, RH, SI, JPC) and Institute of Psychological Medicine and Clinical Neurosciences (VM), School of Medicine, Cardiff University, Cardiff, UK; Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK (TSM); MRC Clinical Trials Unit, London, UK (RK); Wellcome Trust Brenner Building, St James' University Hospital, University of Leeds, Leeds, UK (SR, PQ, MS); Institute of Human Genetics, University Hospital Bonn, Bonn, Germany (VS, PP); Leiden University Medical Center, Department of Clinical Genetics, Leiden, The Netherlands (FJH, JW).
Christopher G
CG
Smith
Affiliations of authors: Institute of Cancer and Genetics (CGS, HW, RH, SI, JPC) and Institute of Psychological Medicine and Clinical Neurosciences (VM), School of Medicine, Cardiff University, Cardiff, UK; Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK (TSM); MRC Clinical Trials Unit, London, UK (RK); Wellcome Trust Brenner Building, St James' University Hospital, University of Leeds, Leeds, UK (SR, PQ, MS); Institute of Human Genetics, University Hospital Bonn, Bonn, Germany (VS, PP); Leiden University Medical Center, Department of Clinical Genetics, Leiden, The Netherlands (FJH, JW).
Hannah
H
West
Affiliations of authors: Institute of Cancer and Genetics (CGS, HW, RH, SI, JPC) and Institute of Psychological Medicine and Clinical Neurosciences (VM), School of Medicine, Cardiff University, Cardiff, UK; Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK (TSM); MRC Clinical Trials Unit, London, UK (RK); Wellcome Trust Brenner Building, St James' University Hospital, University of Leeds, Leeds, UK (SR, PQ, MS); Institute of Human Genetics, University Hospital Bonn, Bonn, Germany (VS, PP); Leiden University Medical Center, Department of Clinical Genetics, Leiden, The Netherlands (FJH, JW).
Rebecca
R
Harris
Affiliations of authors: Institute of Cancer and Genetics (CGS, HW, RH, SI, JPC) and Institute of Psychological Medicine and Clinical Neurosciences (VM), School of Medicine, Cardiff University, Cardiff, UK; Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK (TSM); MRC Clinical Trials Unit, London, UK (RK); Wellcome Trust Brenner Building, St James' University Hospital, University of Leeds, Leeds, UK (SR, PQ, MS); Institute of Human Genetics, University Hospital Bonn, Bonn, Germany (VS, PP); Leiden University Medical Center, Department of Clinical Genetics, Leiden, The Netherlands (FJH, JW).
Shelley
S
Idziaszczyk
Affiliations of authors: Institute of Cancer and Genetics (CGS, HW, RH, SI, JPC) and Institute of Psychological Medicine and Clinical Neurosciences (VM), School of Medicine, Cardiff University, Cardiff, UK; Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK (TSM); MRC Clinical Trials Unit, London, UK (RK); Wellcome Trust Brenner Building, St James' University Hospital, University of Leeds, Leeds, UK (SR, PQ, MS); Institute of Human Genetics, University Hospital Bonn, Bonn, Germany (VS, PP); Leiden University Medical Center, Department of Clinical Genetics, Leiden, The Netherlands (FJH, JW).
Timothy S
TS
Maughan
Affiliations of authors: Institute of Cancer and Genetics (CGS, HW, RH, SI, JPC) and Institute of Psychological Medicine and Clinical Neurosciences (VM), School of Medicine, Cardiff University, Cardiff, UK; Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK (TSM); MRC Clinical Trials Unit, London, UK (RK); Wellcome Trust Brenner Building, St James' University Hospital, University of Leeds, Leeds, UK (SR, PQ, MS); Institute of Human Genetics, University Hospital Bonn, Bonn, Germany (VS, PP); Leiden University Medical Center, Department of Clinical Genetics, Leiden, The Netherlands (FJH, JW).
Richard
R
Kaplan
Affiliations of authors: Institute of Cancer and Genetics (CGS, HW, RH, SI, JPC) and Institute of Psychological Medicine and Clinical Neurosciences (VM), School of Medicine, Cardiff University, Cardiff, UK; Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK (TSM); MRC Clinical Trials Unit, London, UK (RK); Wellcome Trust Brenner Building, St James' University Hospital, University of Leeds, Leeds, UK (SR, PQ, MS); Institute of Human Genetics, University Hospital Bonn, Bonn, Germany (VS, PP); Leiden University Medical Center, Department of Clinical Genetics, Leiden, The Netherlands (FJH, JW).
Susan
S
Richman
Affiliations of authors: Institute of Cancer and Genetics (CGS, HW, RH, SI, JPC) and Institute of Psychological Medicine and Clinical Neurosciences (VM), School of Medicine, Cardiff University, Cardiff, UK; Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK (TSM); MRC Clinical Trials Unit, London, UK (RK); Wellcome Trust Brenner Building, St James' University Hospital, University of Leeds, Leeds, UK (SR, PQ, MS); Institute of Human Genetics, University Hospital Bonn, Bonn, Germany (VS, PP); Leiden University Medical Center, Department of Clinical Genetics, Leiden, The Netherlands (FJH, JW).
Philip
P
Quirke
Affiliations of authors: Institute of Cancer and Genetics (CGS, HW, RH, SI, JPC) and Institute of Psychological Medicine and Clinical Neurosciences (VM), School of Medicine, Cardiff University, Cardiff, UK; Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK (TSM); MRC Clinical Trials Unit, London, UK (RK); Wellcome Trust Brenner Building, St James' University Hospital, University of Leeds, Leeds, UK (SR, PQ, MS); Institute of Human Genetics, University Hospital Bonn, Bonn, Germany (VS, PP); Leiden University Medical Center, Department of Clinical Genetics, Leiden, The Netherlands (FJH, JW).
Matthew
M
Seymour
Affiliations of authors: Institute of Cancer and Genetics (CGS, HW, RH, SI, JPC) and Institute of Psychological Medicine and Clinical Neurosciences (VM), School of Medicine, Cardiff University, Cardiff, UK; Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK (TSM); MRC Clinical Trials Unit, London, UK (RK); Wellcome Trust Brenner Building, St James' University Hospital, University of Leeds, Leeds, UK (SR, PQ, MS); Institute of Human Genetics, University Hospital Bonn, Bonn, Germany (VS, PP); Leiden University Medical Center, Department of Clinical Genetics, Leiden, The Netherlands (FJH, JW).
Valentina
V
Moskvina
Affiliations of authors: Institute of Cancer and Genetics (CGS, HW, RH, SI, JPC) and Institute of Psychological Medicine and Clinical Neurosciences (VM), School of Medicine, Cardiff University, Cardiff, UK; Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK (TSM); MRC Clinical Trials Unit, London, UK (RK); Wellcome Trust Brenner Building, St James' University Hospital, University of Leeds, Leeds, UK (SR, PQ, MS); Institute of Human Genetics, University Hospital Bonn, Bonn, Germany (VS, PP); Leiden University Medical Center, Department of Clinical Genetics, Leiden, The Netherlands (FJH, JW).
Verena
V
Steinke
Affiliations of authors: Institute of Cancer and Genetics (CGS, HW, RH, SI, JPC) and Institute of Psychological Medicine and Clinical Neurosciences (VM), School of Medicine, Cardiff University, Cardiff, UK; Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK (TSM); MRC Clinical Trials Unit, London, UK (RK); Wellcome Trust Brenner Building, St James' University Hospital, University of Leeds, Leeds, UK (SR, PQ, MS); Institute of Human Genetics, University Hospital Bonn, Bonn, Germany (VS, PP); Leiden University Medical Center, Department of Clinical Genetics, Leiden, The Netherlands (FJH, JW).
Peter
P
Propping
Affiliations of authors: Institute of Cancer and Genetics (CGS, HW, RH, SI, JPC) and Institute of Psychological Medicine and Clinical Neurosciences (VM), School of Medicine, Cardiff University, Cardiff, UK; Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK (TSM); MRC Clinical Trials Unit, London, UK (RK); Wellcome Trust Brenner Building, St James' University Hospital, University of Leeds, Leeds, UK (SR, PQ, MS); Institute of Human Genetics, University Hospital Bonn, Bonn, Germany (VS, PP); Leiden University Medical Center, Department of Clinical Genetics, Leiden, The Netherlands (FJH, JW).
Frederik J
FJ
Hes
Affiliations of authors: Institute of Cancer and Genetics (CGS, HW, RH, SI, JPC) and Institute of Psychological Medicine and Clinical Neurosciences (VM), School of Medicine, Cardiff University, Cardiff, UK; Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK (TSM); MRC Clinical Trials Unit, London, UK (RK); Wellcome Trust Brenner Building, St James' University Hospital, University of Leeds, Leeds, UK (SR, PQ, MS); Institute of Human Genetics, University Hospital Bonn, Bonn, Germany (VS, PP); Leiden University Medical Center, Department of Clinical Genetics, Leiden, The Netherlands (FJH, JW).
Juul
J
Wijnen
Affiliations of authors: Institute of Cancer and Genetics (CGS, HW, RH, SI, JPC) and Institute of Psychological Medicine and Clinical Neurosciences (VM), School of Medicine, Cardiff University, Cardiff, UK; Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK (TSM); MRC Clinical Trials Unit, London, UK (RK); Wellcome Trust Brenner Building, St James' University Hospital, University of Leeds, Leeds, UK (SR, PQ, MS); Institute of Human Genetics, University Hospital Bonn, Bonn, Germany (VS, PP); Leiden University Medical Center, Department of Clinical Genetics, Leiden, The Netherlands (FJH, JW). cheadlejp@cardiff.ac.uk.
Jeremy P
JP
Cheadle
D000236:Adenoma / Q000235:genetics*; D002277:Carcinoma / Q000235:genetics*; D015179:Colorectal Neoplasms / Q000235:genetics*; D004249:DNA Damage; D045647:DNA Glycosylases / Q000235:genetics*; D004260:DNA Repair / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D009154:Mutation
D045647:DNA Glycosylases