Switching an O2 sensitive glucose oxidase bioelectrode into an almost insensitive one by cofactor redesign.
In the 5-8 mM glucose concentration range, of particular interest for diabetes management, glucose oxidase bioelectrodes are O2 dependent, which decrease their efficiencies. By replacing the natural cofactor of glucose oxidase, we succeeded in turning an O2 sensitive bioelectrode into an almost insensitive one.
CNRS, CRPP, UPR 8641, Pessac F-33600, France. mano@crpp-bordeaux.cnrs.fr.
Emilie
E
Tremey
Emmanuel
E
Suraniti
Olivier
O
Courjean
Sébastien
S
Gounel
Claire
C
Stines-Chaumeil
Frédéric
F
Louerat
Nicolas
N
Mano
D001234:Aspergillus niger / Q000201:enzymology; D002138:Calibration; D004566:Electrodes; D005947:Glucose / Q000032:analysis*; D005949:Glucose Oxidase / Q000737:chemistry*; D007700:Kinetics; D010100:Oxygen / Q000737:chemistry*
D005949:Glucose Oxidase; D005947:Glucose; D010100:Oxygen