Full-range Fourier domain Doppler optical coherence tomography based on sinusoidal phase modulation.
A novel full-range Fourier domain Doppler optical coherence tomography (full-range FD-DOCT) using sinusoidal phase modulation for B-M scan is proposed. In this sinusoidal B-M scan, zero optical path difference (OPD) position does not move corresponding to lateral scanning points in contrast to linear B-M scan. Since high phase sensitivity arises around the zero OPD position, the proposed full-range FD-DOCT can achieve easily high velocity sensitivity without mirror image around the zero OPD position. Velocity sensitivity dependent on the OPD and the interval of scanning points is examined, and flow velocity detection capability is verified through Doppler imaging of a flow phantom and an in vivo biological sample.
Nan
N
Nan
Xiangzhao
X
Wang
Peng
P
Bu
Zhongliang
Z
Li
Xin
X
Guo
Yan
Y
Chen
Xuan
X
Wang
Fenghua
F
Yuan
Osami
O
Sasaki
D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology*; D004423:Ear / Q000098:blood supply / Q000502:physiology*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D007090:Image Interpretation, Computer-Assisted / Q000295:instrumentation* / Q000379:methods; D017078:Laser-Doppler Flowmetry / Q000295:instrumentation* / Q000379:methods; D051379:Mice; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D041623:Tomography, Optical Coherence / Q000295:instrumentation* / Q000379:methods