Acutissimanide, a new lignan with antioxidant activity isolated from the bark of Quercus acutissima Carruth.
Acutissimanide (1), a new lignin, together with 11 known polyphenols (2-12) were isolated from the bark of the deciduous oak tree, Quercus acutissima Carruth. The structure of compound 1 was determined using multidimensional (1)H and (13)C NMR and mass spectroscopy. The antioxidant properties of compounds 1-12 were investigated using a 1,1-diphenyl-2-picryhydrazyl radical-scavenging assay with compounds 6-11 displaying significant antioxidant activity (EC50 values of 5.2-23.7 μM). Our findings suggest the extracts of Q. acutissima Carruth are a potential source of natural antioxidant additives for use in the food and other allied industries.
a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, School of Chemistry and Biotechnology, Yunnan University of Nationalities , Jingming South Road, Chenggong New District, Kunming, Yunnan 650500 , P.R. China.
Xiao-Li
XL
Zeng
Guang-Miao
GM
Fu
Kai
K
Tian
Jing-Xian
JX
Sun
Hua-Bin
HB
Xiong
Xiang-Zhong
XZ
Huang
Zhi-Yong
ZY
Jiang
D000465:Algorithms; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D024301:Plant Bark / Q000737:chemistry; D059808:Polyphenols / Q000302:isolation & purification; D029963:Quercus / Q000737:chemistry*
D000975:Antioxidants; D004365:Drugs, Chinese Herbal; D017705:Lignans; D059808:Polyphenols; C000593282:acutissimanide
Acutissimanide; Q. acutissima Carruth; antioxidant activity; polyphenols