In between - Proteomics of dog biological fluids.
Dogs are relevant to biomedical research in connection both to veterinary medicine for their role as pets and to basic investigations for their use as animal models in pathology, pharmacology and toxicology studies. Proteomic analysis of biological fluids is less advanced for dogs than for other animal species but a wealth of information has already been gathered, which we summarize in this review. As a remarkable feature, we also assemble here for due reference a number of 2-DE serum/plasma or urine patterns in health and disease; some of them correspond to unpublished data from the University of Veterinary Medicine Vienna.
Institute of Medical Biochemistry, Department of Biomedical Sciences, University of Veterinary Medicine Vienna, Veterinärplatz 1, A-1210 Vienna, Austria.
Ingrid
I
Miller
Institute of Medical Biochemistry, Department of Biomedical Sciences, University of Veterinary Medicine Vienna, Veterinärplatz 1, A-1210 Vienna, Austria.
Andrea
A
Preßlmayer-Hartler
The Kennedy Institute of Rheumatology Division, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7FY, United Kingdom.
Robin
R
Wait
VetCore Facility for Research, University of Veterinary Medicine Vienna, Veterinärplatz 1, A-1210 Vienna, Austria.
Karin
K
Hummel
Gruppo di Studio per la Proteomica e la Struttura delle Proteine, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano; Sezione di Biochimica, Biofisica, Fisiologia ed Immunopatologia, Via Trentacoste, 2, I-20134 Milano, Italy.
Cristina
C
Sensi
Gruppo di Studio per la Proteomica e la Struttura delle Proteine, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano; Sezione di Biochimica, Biofisica, Fisiologia ed Immunopatologia, Via Trentacoste, 2, I-20134 Milano, Italy.
Ivano
I
Eberini
VetCore Facility for Research, University of Veterinary Medicine Vienna, Veterinärplatz 1, A-1210 Vienna, Austria.
Ebrahim
E
Razzazi-Fazeli
Gruppo di Studio per la Proteomica e la Struttura delle Proteine, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano; Sezione di Scienze Farmacologiche, Via Balzaretti 9, I-20133 Milano, Italy. Electronic address: elisabetta.gianazza@unimi.it.
Elisabetta
E
Gianazza
D000485:Allergens / Q000737:chemistry; D000818:Animals; D001798:Blood Proteins / Q000737:chemistry*; D001826:Body Fluids; D004285:Dogs; D015180:Electrophoresis, Gel, Two-Dimensional / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D023421:Models, Animal; D011134:Polysaccharides / Q000737:chemistry; D011507:Proteinuria / Q000378:metabolism; D040901:Proteomics / Q000379:methods*; D016622:Silver Staining; D013696:Temperature; D014556:Urine / Q000737:chemistry
D000485:Allergens; D001798:Blood Proteins; D011134:Polysaccharides
Animal model; Biological fluids; Dog/canine; Proteomics; Veterinary medicine