Silver-catalyzed formal insertion of arynes into Rf-I bonds.
An unprecedented silver-catalyzed formal insertion of arynes into Rf-I (Rf = CF3, C2F5) bonds has been developed. This protocol provides easy access to various ortho-perfluoroalkyl iodoarenes under mild conditions. In this insertion reaction, an ionic atom-transfer reaction of RfI occurs, and a silver-mediated metathesis process is involved in the efficient transfer of the electropositive iodine atom.
Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Ling-Ling Road, Shanghai, 200032 (P.R. China).
Yuwen
Y
Zeng
Jinbo
J
Hu
D001555:Benzene Derivatives / Q000737:chemistry*; D002384:Catalysis; D005461:Fluorine / Q000737:chemistry; D007455:Iodine / Q000737:chemistry; D012835:Silver Nitrate / Q000737:chemistry*; D013237:Stereoisomerism
D001555:Benzene Derivatives; D005461:Fluorine; D012835:Silver Nitrate; D007455:Iodine
arynes; insertions; iodination; perfluoroalkyl iodide; perfluoroalkylation