Comparative scanning electron microscopy of bullous diseases.
The purpose of this study is to compare scanning electron microscopy findings of the blister roof in three distinct bullous diseases: one intraepidermal acantholytic (pemphigus foliaceus); one due to hemidesmosomal dysfunction (bullous pemphigoid); and one secondary to anchoring fibril dysfunction - type VII collagen (dystrophic epidermolysis bullosa). In pemphigus foliaceus, acantholytic phenomena were readily demonstrated. In bullous pemphigoid, the epidermis had a solid aspect. In dystrophic epidermolysis bullosa a net was seen in the blister roof.
Universidade Federal de Pelotas, Pelotas, RS, Brazil.
Hiram Larangeira de
HL
Almeida
Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Gabriela
G
Rossi
Universidade Católica de Pelotas, Pelotas, RS, Brazil.
Octavio Ruschel
OR
Karam
CPA-CT, Empresa Brasileira de Pesquisa Agropecuária, Pelotas, RS, Brazil.
Nara Moreira
NM
Rocha
Universidade Federal de Pelotas, Pelotas, RS, Brazil.
Ricardo Marques E
RM
Silva
D016108:Epidermolysis Bullosa Dystrophica / Q000473:pathology*; D006801:Humans; D008855:Microscopy, Electron, Scanning / Q000379:methods*; D012872:Skin Diseases, Vesiculobullous / Q000473:pathology*