A gold-catalysed fully intermolecular oxidation and sulfur-ylide formation sequence on ynamides.
An efficient C-O, C-S and C-C bond-forming sequence leads to functionalised compounds bearing sulfur-substituted quaternary carbons. Ynamides are employed as diazo-equivalents to access the [2,3]-sigmatropic rearrangements of allyl sulfonium ylides by a three-component chemoselective oxidation and intermolecular ylide formation.
School of Chemistry, University of Birmingham, Edgbaston, B15 2TT, Birmingham, UK. p.w.davies@bham.ac.uk.
Mickaël
M
Dos Santos
Paul W
PW
Davies