Outcomes of a ventilator-associated pneumonia bundle on rates of ventilator-associated pneumonia and other health care-associated infections in a long-term acute care hospital setting.
Long-term trends in ventilator-associated pneumonia (VAP) rates, and other health care-associated infections, were examined prior to, during, and after introduction of a VAP bundle in a long-term acute care hospital setting. VAP incidence rate declined in a step-wise fashion and reached a null value. Incidence rates of bacteremia from any cause declined in a similar fashion. The incidence rates of vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus colonization or infection rates also decreased, but that of Clostridium difficile infection did not. VAP in the long-term acute care hospital setting can be controlled over time with implementation of Centers for Disease Control and Prevention-based VAP bundle. This outcome also may decrease certain other health care-associated infections.
Section of Infectious Disease, Boston University School of Medicine, Boston, MA; Department of Medicine, Radius Specialty Hospital, Boston, MA.
Carol A
CA
Sulis
Section of Pulmonary and Critical Care Medicine, Boston University School of Medicine, Boston, MA.
Allan J
AJ
Walkey
Department of Medicine, Radius Specialty Hospital, Boston, MA.
Yafet
Y
Abadi
Department of Medicine, Radius Specialty Hospital, Boston, MA; Section of Pulmonary and Critical Care Medicine, Boston University School of Medicine, Boston, MA.
Christine
C
Campbell Reardon
Department of Medicine, Radius Specialty Hospital, Boston, MA; Section of Pulmonary and Critical Care Medicine, Boston University School of Medicine, Boston, MA. Electronic address: mjbrady@bu.edu.
Martin
M
Joyce-Brady
D016360:Clostridioides difficile / Q000302:isolation & purification; D003422:Critical Care; D016983:Enterococcus / Q000302:isolation & purification; D016908:Gram-Positive Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control*; D006761:Hospitals; D006801:Humans; D015994:Incidence; D017053:Infection Control / Q000379:methods*; D008134:Long-Term Care; D053717:Pneumonia, Ventilator-Associated / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control*; D013211:Staphylococcus aureus / Q000302:isolation & purification
HAI; LTACH; VAP