[Pepmhigus of the mucous membrane of the mouth].
Pemphigus is a rare autoimmune disease of the skin and mucous membranes. It is characterized by autoantibodies directed against the desmosomal adhesion proteins of epithelial cells (desmoglein type I and III) resulting in acantholysis of the epithelium. Painful blisters or erosions are typical clinical findings. Pemphigus is a severe disease that may be fatal. Early diagnosis of pemphigus is important in order to be able to start the treatment as soon as possible and to halt the progression of the disease and avoid serious secondary infections.
Anna
A
Haimala
Liisa
L
Väkevä
Valtteri
V
Häyry
Jaana
J
Hagström
D003937:Diagnosis, Differential; D018450:Disease Progression; D042241:Early Diagnosis; D006801:Humans; D009061:Mouth Mucosa / Q000473:pathology*; D010392:Pemphigus / Q000175:diagnosis* / Q000628:therapy