Distribution pattern of Sjögren's syndrome: a sialographical study.
OBJECTIVE
The present controlled sialographical study was conducted to learn more from the horizontal and vertical symmetry of the ductal lesions of the major salivary glands in primary (pSS) and secondary (sSS) forms of the disease.


METHODS
A total of 98 patients (38 pSS patients, 38 sSS patients, 22 control subjects) were included in the study. Contrast radiography of both parotid and submandibular glands was performed within the same session. A 6-point scoring system allowed summary indexes for each of the glands to be calculated.


RESULTS
Pansialography was accomplished within 30 min each. The sparsity of the branching pattern of the ducts was the most frequent pathological finding. In pSS, horizontal symmetry was more pronounced in the parotid glands, whereas in sSS it was more pronounced in the submandibular glands. The most discriminating features were the width of the peripheral ducts in the parotid and the number of acinar dilatations in the submandibular glands. The most advanced lesions were found in the left parotid gland.


CONCLUSIONS
The peripheral ducts are more affected by SS than the main excretory duct. There is a tendency for asymmetric involvement of the parotid glands in pSS and of the submandibular glands in sSS. Parotid glands are globally more involved than submandibular glands. Differential diagnosis between pSS and sSS cannot be accomplished by means of pansialography alone. Left parotid sialography is recommended for routine use.
Department of Radiology and Nuclear Medicine, Free University of Berlin, Hindenburgdamm 30, 12200, Berlin, Germany, werner.golder@orange.fr.
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Stiller
D000293:Adolescent; D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D008875:Middle Aged; D010306:Parotid Gland / Q000000981:diagnostic imaging*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012796:Sialography / Q000379:methods*; D012859:Sjogren's Syndrome / Q000000981:diagnostic imaging*; D013363:Submandibular Gland / Q000000981:diagnostic imaging*; D055815:Young Adult