Successful treatment of necrobiotic xanthogranuloma with total glucosides of paeony.
Necrobiotic xanthogranuloma (NXG) is a rare granulomatous condition that is often associated with a paraproteinemia and in some cases multiple myeloma. We report a case of isolated NXG that responded very well to total glucosides of paeony treatment. Characteristic clinical and histological features of NXG are presented, as well as a discussion regarding management and the use of glucosides of paeony. Treatment with total glucosides of paeony is an effective, safe treatment, which avoids the side effects associated with systemic corticosteroid or cytotoxic agent therapy.
Departments of Dermatology, The First Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Shuang
S
Li
Ai-Jun
AJ
Chen
Sheng
S
Fang
Hui
H
Li
D003879:Dermatologic Agents / Q000302:isolation & purification / Q000627:therapeutic use*; D005260:Female; D005960:Glucosides / Q000302:isolation & purification / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D058252:Necrobiotic Xanthogranuloma / Q000175:diagnosis / Q000188:drug therapy*; D029596:Paeonia / Q000737:chemistry; D008517:Phytotherapy; D010936:Plant Extracts / Q000302:isolation & purification / Q000627:therapeutic use*; D018517:Plant Roots; D010946:Plants, Medicinal; D012074:Remission Induction; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D016896:Treatment Outcome
D003879:Dermatologic Agents; D005960:Glucosides; D010936:Plant Extracts
necrobiotic xanthogranuloma; periorbital; total glucosides of paeonys