Fluctuations in C-reactive protein in a hepatoblastoma patient with thrombocytosis.
We observed the changes in serum levels of interleukin 6 (IL-6) and C-reactive protein (CRP) in a patient with hepatoblastoma exhibiting thrombocytosis. The concomitant changes of IL-6 and CRP concentrations after the initiation of chemotherapy, in the absence of infection, suggested that the IL-6, which is synthesized in hepatoblastoma cells and induces thrombocytosis, also stimulated CRP production in the present case. IL-6 is thought to play an important role in thrombocytosis in hepatoblastoma.
Department of Pediatrics;
Yuya
Y
Sato
Department of Pediatrics;
Ayaka
A
Kokubu
Department of Pediatrics;
Keitaro
K
Fukushima
Department of Pediatrics;
Mayuko
M
Okuya
Department of Pediatrics;
Susumu
S
Hagisawa
Department of Pediatrics;
Hidemitsu
H
Kurosawa
Department of Pediatrics;
Kenichi
K
Sugita
Department of Pediatrics;
Osamu
O
Arisaka
Department of Pediatric Surgery, Dokkyo Medical University, Japan.
Kentaro
K
Okamoto
Department of Pediatric Surgery, Dokkyo Medical University, Japan.
Takashi
T
Tsuchioka
C-reactive protein; hepatoblastoma; interleukin-6.; thrombocytosis