Sarcopenia and sarcopenic obesity classifications and cardiometabolic risks in older women.
The purpose of this study was to examine the association between sarcopenia and sarcopenic obesity (SO) with cardiometabolic risk factors in postmenopausal women. 149 volunteers (67.17±6.12 years) underwent body composition assessment using dual energy X-ray absorptiometry (DXA) and had analyzed blood samples collected for lipid profile, glucose metabolism and C-reactive protein (CRP). Sarcopenia was defined as an appendicular fat-free mass (AFFM) divided by height squared ≤5.45 kg/m(2) while SO was classified based on the residuals of a regression. Waist circumference (WC) and arterial blood pressure were also measured. Student's t-tests and correlations were used for analyses. Prevalence of sarcopenia and SO were respectively 16.8 and 21.5%. WC was significantly correlated with all the examined risk factors. AFFM relative to height squared was positively correlated with systolic blood pressure (SBP) and diastolic blood pressure (DBP), CRP, insulinaemia, HOMA score, and those classified as sarcopenic presented lower HOMA score when compared to nonsarcopenic. Regarding SO, although volunteers classified presented significantly higher fat mass (FM) and lower AFFM, it was not observed association with the examined risk factors. These findings support the association between WC and cardiometabolic risk factors in older women. In contrast, the approaches used to define sarcopenia and SO are not associated with cardiometabolic impairments.
Physiology of Exercise and Health Research Group, Faculty of Physical Education of University of Brasília, Campus Darcy Ribeiro, Brasília, Brazil; Federal Institute of Piauí, Floriano, Brazil.
Enivaldo Pereira
EP
dos Santos
Physiology of Exercise and Health Research Group, Faculty of Physical Education of University of Brasília, Campus Darcy Ribeiro, Brasília, Brazil; University of Brasília, Brasília, Brazil. Electronic address: andrebonadias@gmail.com.
André Bonadias
AB
Gadelha
University of Brasília, Brasília, Brazil.
Marisete Peralta
MP
Safons
University of Brasília, Brasília, Brazil.
Otávio Toledo
OT
Nóbrega
University of Brasília, Brasília, Brazil.
Ricardo Jacó
RJ
Oliveira
Physiology of Exercise and Health Research Group, Faculty of Physical Education of University of Brasília, Campus Darcy Ribeiro, Brasília, Brazil; University of Brasília, Brasília, Brazil.
Ricardo Moreno
RM
Lima
D015502:Absorptiometry, Photon; D000368:Aged; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000032:analysis; D001795:Blood Pressure Determination; D001823:Body Composition; D002097:C-Reactive Protein / Q000378:metabolism; D003430:Cross-Sectional Studies; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D008055:Lipids / Q000097:blood; D009765:Obesity / Q000453:epidemiology*; D015995:Prevalence; D012307:Risk Factors; D055948:Sarcopenia / Q000453:epidemiology*; D055105:Waist Circumference
D015415:Biomarkers; D001786:Blood Glucose; D008055:Lipids; D002097:C-Reactive Protein
Aging; DXA; Metabolic impairments; Muscle mass