Dietary exposure to chloropropanols of secondary school students in Hong Kong.
This paper reports levels of 3-monochloropropan-1,2-diol (3-MCPD) and 1,3-dichloro-2-propanol (1,3-DCP) in a wide range of food items and estimates their dietary exposure for secondary school students in Hong Kong. Dietary exposure to chloropropanols was estimated using local food consumption data obtained from secondary school students in 2000 and the concentrations of 3-MCPD and 1,3-DCP in food samples taken from the local market. The dietary exposure to 3-MCPD for an average secondary school student consumer was estimated to be 0.063-0.150 µg kg(-1) body weight (bw) day(-1), whilst that for the high consumer was 0.152-0.300 µg kg(-1) bw day(-1). Both estimates fell below the provisional maximum tolerable daily intake of 2 µg kg(-1) bw established by the Joint Expert Committee on Food Additives (JECFA) and amounted to less than 20% of this safety reference value. The dietary exposure to 1,3-DCP for an average secondary school student consumer was estimated to be 0.003-0.019 µg kg(-1) bw day(-1), whilst that for the high consumer was 0.009-0.040 µg kg(-1) bw day(-1). The resulting margins of exposures were of low concern for human health. It could be concluded that both the average and high secondary school student consumers were unlikely to experience major toxicological effects of 3-MCPD and 1,3-DCP.
a Centre for Food Safety, Food and Environmental Hygiene Department , Hong Kong Special Administrative Region , China.
J C W
JC
Yau
K P
KP
Kwong
S W C
SW
Chung
Y Y
YY
Ho
Y
Y
Xiao
D000293:Adolescent; D004032:Diet; D004781:Environmental Exposure / Q000032:analysis*; D005506:Food Contamination / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D006723:Hong Kong; D006801:Humans; D008452:Maximum Allowable Concentration; D012574:Schools; D013334:Students; D000517:alpha-Chlorohydrin / Q000031:analogs & derivatives* / Q000032:analysis
C033489:1,3-dichloro-2-propanol; D000517:alpha-Chlorohydrin
1,3-dichloro-2-propanol (1,3-DCP); 3-monochloropropan-1,2-diol (3-MCPD); Hong Kong; chloropropanols; dietary exposure