Enantioselective allylic amination of trifluoromethyl group substituted racemic and unsymmetrical 1,3-disubstituted allylic esters by palladium catalysts.
The palladium-catalyzed regio- and enantioselective allylic amination of trifluoromethyl group substituted racemic and unsymmetrical 1,3-disubstituted allylic esters has been accomplished. The enantioselective formation of the α-type allylic amines was attained by the dynamic kinetic asymmetric transformation (DYKAT).
Department of Chemistry, College of Humanities & Sciences, Nihon University , Sakurajosui, Setagaya-ku, Tokyo 156-8550, Japan.
Motoi
M
Kawatsura
Shou
S
Terasaki
Maki
M
Minakawa
Takuya
T
Hirakawa
Kazunori
K
Ikeda
Toshiyuki
T
Itoh