Risk factors of nocturia (two or more voids per night) in Chinese people older than 40 years.
OBJECTIVE
To explore the risk factors of nocturia in Chinese inhabitants aged ≥40 years.


METHODS
A randomized, community-based, cross-sectional study was performed on 10,160 inhabitants ≥40 years old in mainland China, via a stratified sampling approach. A questionnaire, including socio-demographics, lifestyle factors and medical history, was completed. Nocturia was defined as a threshold of two or more voids per night. Differences in prevalence between age and gender groups were ascertained by the chi-squared test. Gender-related factors were evaluated by multivariate logistic regression analysis. P < 0.05 was considered to be statistically significant.


RESULTS
Data on 9,637 (94.9%) people aged 59.6 ± 9.7 years qualified for final statistical analysis. The overall prevalence of nocturia was 31.7% (3,053/9,637), and this increased with age (P < 0.001). Nocturia was significantly associated with cardiovascular disease and overactive bladder symptom score (OABSS) (P < 0.05), while sporting activities were protective (P < 0.001). Diabetes mellitus (DM) was significantly correlated with nocturia in men (P < 0.05), whereas hypertension was correlated with nocturia in women (P < 0.05). No correlation was found between nocturia and education level, occupation, civil status, tea consumption, body mass index (BMI), female birth history, and International Prostate Symptom Score.


CONCLUSIONS
In Chinese people aged ≥40 years, nocturia is associated with aging, OABSS, cardiovascular disease, hypertension, and DM. Sporting activities are negatively associated with nocturia.
Urodynamics Centre, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.|Department of Nephrology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.|Institute of Clinical Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Lu
L
Wen
Grade 2011 (Seven-Years Clinical Medicine of Zhengzhou University), First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yi Bo
YB
Wen
Department of Endocrinology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhi Min
ZM
Wang
Urodynamics Centre, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.|Institute of Clinical Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.|Department of Urology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Jian Guo
JG
Wen
Institute of Clinical Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhen Zhen
ZZ
Li
Medical Records Department, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xiao Ping
XP
Shang
Department of Nephrology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhang Suo
ZS
Liu
Urodynamics Centre, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Liang Hua
LH
Jia
Department of Endocrinology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Gui Jun
GJ
Qin
Department of Urology, Radboud University Medical Centre, Nijmegen, The Netherlands.
John
J
Heesakkers
Department of Surgery/Urology, McGill University, Montreal, QC, Canada.
Jacques
J
Corcos
Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Jens Christian
JC
Djurhuus
D000367:Age Factors; D000368:Aged; D044466:Asian People; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000503:physiopathology; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000652:urine; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D053158:Nocturia / Q000453:epidemiology*; D012307:Risk Factors; D012737:Sex Factors; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D013662:Tea; D053201:Urinary Bladder, Overactive / Q000453:epidemiology / Q000503:physiopathology
D013662:Tea
aging; cardiovascular disease; diabetes mellitus; elderly people; nocturia; risk factors; sporting activities