A Case Report of Turner Syndrome with Graves' Disease during Recombinant Human GH Therapy and Review of Literature.
An increased incidence of Hashimoto thyroiditis has been reported in patients with Turner syndrome, but several cases of Graves' disease were also described ten to 20 years ago. We report the case of a patient with Turner syndrome who developed Graves' disease, 3 years after successful treatment with recombinant human growth hormone (GH). A diagnosis of Graves' disease was made and treatment with thiamazole was started, which resulted in normalization of the thyroid function. It is important to monitor thyroid function as well as growth parameters in patients with Turner syndrome.
Department of General Pediatrics, Nerima-Hikarigaoka Nihon University Hospital, Nihon University School of Medicine, Tokyo, Japan.
Makio
M
Nakagawa
Department of General Pediatrics, Nerima-Hikarigaoka Nihon University Hospital, Nihon University School of Medicine, Tokyo, Japan.
Yasuji
Y
Inamo
Department of General Pediatrics, Nerima-Hikarigaoka Nihon University Hospital, Nihon University School of Medicine, Tokyo, Japan.
Kensuke
K
Harada
Graves’ disease; Turner syndrome; hyperthyroidism; recombinant human growth hormone therapy