[Specific features of materials for initial pulpitis treatment].
The aim of the current study was to assess antibacterial and cytotoxic properties of Biodentine (Septodont), Rootdent (TehnoDent) and adhesive Futurabond НР (Voco). Two lines of experiments were carried out using cements water solutions and firm tablet-like samples (made by means of special pattern). Citotoxic activity was tested on NCTC L929 mice line fibroblasts culture. All the examined materials showed antibacterial activity against E. coli, S. aureus, C. albiсans, St. faecalis, mostly evident in Futurabond and the poorest in Biodentine samples. As for cytotoxic properties, Biodentine proved not to suppress metabolic activity stimulating odontotropic impact. The results confirm the analyzed materials to be a useful tool for deep caries lesions and initial pulpitis treatment.
E V
EV
Ivanova
G S
GS
Shamkhalov
N A
NA
Dmitrieva
Z R
ZR
Akhmedova
D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects; D002460:Cell Line; D003407:Creosote / Q000009:adverse effects / Q000494:pharmacology*; D004249:DNA Damage; D003731:Dental Caries / Q000382:microbiology; D003782:Dental Pulp / Q000098:blood supply / Q000382:microbiology*; D004338:Drug Combinations; D013293:Enterococcus faecalis / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D005347:Fibroblasts / Q000187:drug effects / Q000382:microbiology; D006847:Hydrocarbons, Iodinated / Q000009:adverse effects / Q000494:pharmacology*; D006940:Hyperemia / Q000382:microbiology; D008689:Methacrylates / Q000009:adverse effects / Q000494:pharmacology*; D051379:Mice; D011671:Pulpitis / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects; D013943:Thymol / Q000009:adverse effects / Q000494:pharmacology*
D000890:Anti-Infective Agents; D004338:Drug Combinations; D006847:Hydrocarbons, Iodinated; D008689:Methacrylates; C512545:futurabond NR; D013943:Thymol; D003407:Creosote; C034472:Septodont