Parameters of cellular and humoral immunity in experimental hyperthyroidism and its correction.
We demonstrate changes in cellular and humoral immunity in animals with experimental hyperthyroidism induced by chronic administration of potassium iodide (KI) solution. KI increased the weight and cellularity of the thymus and spleen and number of antibody-forming cells to sheep red blood cells and modified the relative content of T cell subpopulations. Phytosorption complex LimfoFit modifying cellular and humoral immunity affected only its individual parameters in hyperthyroid animals.
Research Institute of Clinical and Experimental Lymphology, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk, Russia, robin@physiol.ru.
M V
MV
Robinson
T A
TA
Obut
E V
EV
Melnikova
V A
VA
Trufakin
D000818:Animals; D004353:Drug Evaluation, Preclinical; D006980:Hyperthyroidism / Q000097:blood / Q000276:immunology* / Q000628:therapy; D007111:Immunity, Cellular; D056724:Immunity, Humoral; D007155:Immunologic Factors / Q000627:therapeutic use*; D018655:Lymphocyte Count; D008297:Male; D008808:Mice, Inbred CBA; D012756:Sheep; D013154:Spleen / Q000276:immunology / Q000473:pathology; D013950:Thymus Gland / Q000276:immunology / Q000473:pathology; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D007155:Immunologic Factors; D014284:Triiodothyronine; D013974:Thyroxine