Spinal epidural lipomatosis in lumbar magnetic resonance imaging scans.
The goal of this study was to quantify the frequency of advanced spinal epidural lipomatosis (SEL) detected on lumbar magnetic resonance imaging (MRI) scans performed at the authors' hospital and to compare the frequency, cause, and progression of SEL in these cases with that reported in the literature. The total number of MRI examinations of the lumbar spine performed at this hospital over 45 months was 1498 (705 men and 793 women; mean age, 60.3 years). After the MRI data were reduced (T1- and T2-weighted sagittal and axial images) on the basis of the exclusion criteria, the anterior and posterior diameters of the dural sac and spinal canal were measured, as well as the thickness of the epidural fat. On the basis of these parameters, the severity of SEL was classified as grade 0 to grade III. Five cases of grade III SEL were diagnosed. The frequency of grade III SEL noted in this study was 0.33% (5/1498). Obesity (body mass index greater than 27.5) was noted in 3 cases, and the use of exogenous corticosteroids was noted in 3 cases. Exogenous steroid usage associated with advanced SEL in this study was greater than that reported in the literature. Most symptoms of SEL progress slowly, and early diagnosis allows for a dose reduction of the prescribed steroids. Thus, lumbar MRI examinations should be conducted aggressively in patients with exogenous steroid use and presenting with low back pain or buttock pain.
Hisashi
H
Sugaya
Toshikazu
T
Tanaka
Takeshi
T
Ogawa
Hajime
H
Mishima
D000368:Aged; D002081:Buttocks; D004824:Epidural Space; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects; D006801:Humans; D008068:Lipomatosis / Q000175:diagnosis* / Q000209:etiology; D017116:Low Back Pain / Q000209:etiology; D008159:Lumbar Vertebrae; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D010146:Pain / Q000209:etiology; D013122:Spinal Diseases / Q000175:diagnosis* / Q000209:etiology
D005938:Glucocorticoids