Prospective chest pain evaluation in the emergency department with use of high-sensitivity C-reactive protein (PROCEED-CRP study).
We evaluated the clinical value of a single measurement of high-sensitivity C-reactive protein (hs- CRP) in patients presenting to the emergency department with chest pain. We screened 408 consecutive patients of whom 292 comprised the final cohort for this study. Hs-CRP measured in the emergency department (ED) in patients presenting with chest pain and admitted for evaluation of acute myocardial infarction was neither sensitive nor specific in predicting acute myocardial infarction, myocardial ischemia on SPECT imaging, need for coronary revascularization, or cardiovascular or all-cause rehospitalization at 30 days. In addition, use of a specific CRP cut off >1 was not associated with an increase in all-cause rehospitalization at 30 days.
Costin N
CN
Ionescu
Michael P
MP
Chrissoheris
Hannah B
HB
Slim
Martin
M
Slade
Joyce
J
Oen-Hsiao
Thomas J
TJ
Donohue
Amenuve
A
Bekui
Andre E
AE
Ghantous
D000208:Acute Disease; D000368:Aged; D002097:C-Reactive Protein / Q000032:analysis*; D002317:Cardiovascular Agents / Q000008:administration & dosage; D002637:Chest Pain / Q000097:blood*; D015897:Comorbidity; D004636:Emergency Service, Hospital / Q000458:organization & administration*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000175:diagnosis; D017202:Myocardial Ischemia / Q000097:blood* / Q000175:diagnosis*; D010359:Patient Readmission / Q000706:statistics & numerical data; D062645:Percutaneous Coronary Intervention / Q000706:statistics & numerical data; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index
D002317:Cardiovascular Agents; D002097:C-Reactive Protein