Linking an α-tocopherol derivative to cobalt(0) nanomagnets: magnetically responsive antioxidants with superior radical trapping activity and reduced cytotoxicity.
Covalent attachment of a phenolic antioxidant analogue of α-tocopherol to graphite-coated magnetic cobalt nanoparticles (CoNPs) provided a novel magnetically responsive antioxidant capable of preventing the autoxidation of organic materials and showing a reduced toxicity toward human cells.
Department of Chemistry "U. Schiff'', Università di Firenze, Via della Lastruccia, 3-13, 50019, Sesto Fiorentino (Italy), Fax: (+39) 055-4573531.
Caterina
C
Viglianisi
Veronica
V
Di Pilla
Stefano
S
Menichetti
Vincent M
VM
Rotello
Gabriele
G
Candiani
Chiara
C
Malloggi
Riccardo
R
Amorati
D000975:Antioxidants / Q000737:chemistry*; D002470:Cell Survival / Q000187:drug effects; D003035:Cobalt / Q000737:chemistry*; D005609:Free Radicals / Q000737:chemistry / Q000633:toxicity; D006108:Graphite / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D008280:Magnetics; D058185:Magnetite Nanoparticles / Q000737:chemistry* / Q000633:toxicity; D010084:Oxidation-Reduction; D024502:alpha-Tocopherol / Q000737:chemistry*
D000975:Antioxidants; D005609:Free Radicals; D058185:Magnetite Nanoparticles; D003035:Cobalt; D006108:Graphite; D024502:alpha-Tocopherol
antioxidants; cobalt; cytotoxicity; nanoparticles; tocopherol