Palladium-catalyzed three-component reaction of N-tosylhydrazone, norbornene and aryl halide.
A palladium-catalyzed three-component reaction of N-tosylhydrazone, norbornene and aryl halide has been demonstrated. In this reaction, an intermolecular Heck-type reaction occurs, which is followed by the alkyl palladium carbene migratory insertion process. This transformation provides an efficient and convenient methodology for the double functionalization of norbornene with good to excellent yields.
School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China.
Fangdong
F
Hu
Ying
Y
Xia
Zhenxing
Z
Liu
Chen
C
Ma
Yan
Y
Zhang
Jianbo
J
Wang