Cutting through complexity: the proteolytic properties of alternate immunoproteasome complexes.
The proteasome core interacts with different activators and incorporates alternate active subunits, thereby generating a diverse pool of subspecies. The enzymatic properties of these different species are not well understood. In this issue of Chemistry & Biology, Raule and colleagues present a comprehensive enzymatic characterization of immunoproteasome complexes associated with the proteasome activator PA28.
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Ciyu
C
Yang
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: marion.schmidt@einstein.yu.edu.
Marion
M
Schmidt
D046988:Proteasome Endopeptidase Complex / Q000737:chemistry* / Q000378:metabolism*
D046988:Proteasome Endopeptidase Complex