[Micropenis].
Micropenis represents a clinical sign that should be diagnosed at birth (or in utero) by the detection of a normally structured penis with a length 2.5 SD below the mean for age. Micropenis can be classified as due to deficient testosterone secretion or action. Evaluation of the gonadotropic and testicular function during the mini-puberty is often helpful in evaluating the etiology. Management of micropenis should focus on achieving a suitable penis length, in order to allow an adequate urination, normal sexual intercourses and a good self-body image. Irrespective of the underlying cause, a short course of T should be tried in patients with micropenis to assess the ability of the penis to respond to it. Topical 5a-dihydrotestosterone gel has also been reported to be effective. Children with hypopituitarism and GH deficiency respond to appropriate hormonal therapy. Psychological counseling is helpful and often necessary.
Endocrinologie pédiatrique, faculté de médecine Paris 11, centre de référence des anomalies du développement sexuel, hôpital Bicêtre, 78, rue du Général-Leclerc, 94270 Le Kremlin-Bicêtre, France. Electronic address: claire.bouvattier@bct.aphp.fr.
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Bouvattier
D000728:Androgens / Q000627:therapeutic use; D013196:Dihydrotestosterone / Q000627:therapeutic use; D019382:Human Growth Hormone / Q000172:deficiency; D006801:Humans; D007018:Hypopituitarism / Q000151:congenital / Q000175:diagnosis; D008297:Male; D010413:Penis / Q000002:abnormalities* / Q000254:growth & development; D014564:Urogenital Abnormalities / Q000175:diagnosis / Q000209:etiology / Q000628:therapy
D000728:Androgens; D013196:Dihydrotestosterone; D019382:Human Growth Hormone