Electron transferases.
The flavin isoalloxazine ring in electron transferases functions in a redox capacity, being able to take up electrons from a donor to subsequently deliver them to an acceptor. The main characteristics of these flavoproteins, including their unique ability to mediate obligatory processes of two-electron transfers with those involving single-electron transfer, are here described. To illustrate the versatility of these proteins, the acquired knowledge of the function of the two electron transferases involved in the cyanobacterial photosynthetic electron transfer from photosystem I to NADP(+) is presented. Many aspects of their biochemistry and biophysics have been extensively characterized using site-directed mutagenesis, steady-state and transient kinetics, spectroscopy, calorimetry, X-ray crystallography, electron paramagnetic resonance, and computational methods.
Department of Biochemistry and Molecular and Cellular Biology, Institute for Biocomputation and Physics of Complex Systems, Zaragoza, Spain.
Patricia
P
Ferreira
Marta
M
Martínez-Júlvez
Milagros
M
Medina
D000458:Cyanobacteria / Q000378:metabolism; D004579:Electron Transport / Q000502:physiology*; D045222:Electron Transport Chain Complex Proteins / Q000378:metabolism*; D010084:Oxidation-Reduction; D010788:Photosynthesis / Q000502:physiology
D045222:Electron Transport Chain Complex Proteins