A new pyrene-based Schiff-base: a selective colorimetric and fluorescent chemosensor for detection of Cu(II) and Fe(III).
A new receptor 1 was prepared, for the detection of Cu2+ and Fe3+ in solutions as a colorimetric and fluorescent sensor, respectively. Receptor 1 shows highly selective and sensitive recognition toward Cu2+ and Fe3+ by naked eye UV-Vis and fluorescent color changes in aqueous solution (DMSO/H2O=8/2, v/v), respectively. The sensitivity toward Cu2+ or Fe3+ was not interfered with by the presence of other metal ions such as Mg2+, Cd2+, Ag+, Zn2+, Ni2+, Co2+, Mn2+, Cr3+, Ca2+, Na+, Pb2+, K+, Fe2+, Li+ and Hg2+ ions. Receptor 1 can be used for semi-quantitative recognition of Cu2+ ions at ppm level. The fluorescence microscopy experiments showed that the receptor is efficient for detection of Fe3+ in vitro, developing a good image of the biological organelles.
Department of Applied Chemistry, Providence University, 200, Sec. 7, Taiwan Boulevard, Shalu Dist, Taichung City 43301, Taiwan.
Yeshwant Ramchandra
YR
Bhorge
Department of Applied Chemistry, Providence University, 200, Sec. 7, Taiwan Boulevard, Shalu Dist, Taichung City 43301, Taiwan.
Haw-Tyng
HT
Tsai
Department of Applied Chemistry, Providence University, 200, Sec. 7, Taiwan Boulevard, Shalu Dist, Taichung City 43301, Taiwan.
Keh-Feng
KF
Huang
Department of Applied Chemistry, Providence University, 200, Sec. 7, Taiwan Boulevard, Shalu Dist, Taichung City 43301, Taiwan.
Albert J
AJ
Pape
Graduate Institute of Biomedical Sciences, National Chung Hsing University, 250 Kuo-Kuang Road, Taichung 40227, Taiwan.
Sudhakar Narasimha
SN
Janaki
Department of Applied Chemistry, Providence University, 200, Sec. 7, Taiwan Boulevard, Shalu Dist, Taichung City 43301, Taiwan. Electronic address: ypyen@pu.edu.tw.
Yao-Pin
YP
Yen
D001667:Binding, Competitive; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D003124:Colorimetry; D003300:Copper / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D007477:Ions; D007501:Iron / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008856:Microscopy, Fluorescence; D011721:Pyrenes / Q000737:chemistry*; D012545:Schiff Bases / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet
D005290:Ferric Compounds; D005456:Fluorescent Dyes; D007477:Ions; D011721:Pyrenes; D012545:Schiff Bases; D012997:Solvents; D003300:Copper; C030984:pyrene; D007501:Iron; C004482:1-aminopyrene
Cell imaging; Chemosensor; Colorimetric; Cu(2+) and Fe(3+) ions; Fluorescence; Pyrene derivative