Carbapenemase genes and genetic platforms in Gram-negative bacilli: Enterobacteriaceae, Pseudomonas and Acinetobacter species.
The emergence and rapid spread of carbapenemases in Enterobacteriaceae, Pseudomonas and Acinetobacter (EPA) species is becoming a major public health crisis worldwide, and is responsible for large number of hospital-acquired and nosocomial infections. In this article, we review the current knowledge on the classification, phylogeny and genetic platforms of the main carbapenemases already described in Gram-negative bacteria.
Aix-Marseille Université, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France.
S M
SM
Diene
J-M
JM
Rolain
D000150:Acinetobacter / Q000201:enzymology* / Q000235:genetics*; D001426:Bacterial Proteins / Q000145:classification / Q000235:genetics* / Q000378:metabolism; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004755:Enterobacteriaceae / Q000201:enzymology* / Q000235:genetics*; D005798:Genes, Bacterial; D006801:Humans; D010802:Phylogeny; D011549:Pseudomonas / Q000201:enzymology* / Q000235:genetics*; D001618:beta-Lactamases / Q000145:classification / Q000235:genetics* / Q000378:metabolism
D001426:Bacterial Proteins; D004269:DNA, Bacterial; D001618:beta-Lactamases; C063912:carbapenemase
Acinetobacter; Enterobacteriaceae; Pseudomonas; carbapenemases; multidrug-resistant bacteria