The design and synthesis of a hydrophilic core-shell-shell structured magnetic metal-organic framework as a novel immobilized metal ion affinity platform for phosphoproteome research.
In this work, polydopamine (PDA)-coated magnetic microspheres with surface modification of zirconium-based MOFs were synthesized for the first time. The as-synthesized Fe3O4@PDA@Zr-MOF composites were successfully applied as a novel immobilized metal ion affinity platform for phosphoproteome research.
Department of Chemistry & Institutes of Biomedical Science, Fudan University, Shanghai 200433, China. chdeng@fudan.edu.cn.
Man
M
Zhao
Chunhui
C
Deng
Xiangmin
X
Zhang
D057927:Hydrophobic and Hydrophilic Interactions; D007211:Indoles / Q000737:chemistry; D058185:Magnetite Nanoparticles / Q000737:chemistry; D008863:Microspheres; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D010316:Particle Size; D010750:Phosphoproteins / Q000032:analysis*; D011108:Polymers / Q000737:chemistry; D020543:Proteome / Q000032:analysis*; D013499:Surface Properties; D015040:Zirconium / Q000737:chemistry
D007211:Indoles; D058185:Magnetite Nanoparticles; D009942:Organometallic Compounds; D010750:Phosphoproteins; D011108:Polymers; D020543:Proteome; C568283:polydopamine; D015040:Zirconium