GnRH antagonist-based protocols for in vitro fertilization.
In this chapter we elaborate on the intricacies of employing GnRH antagonists for prevention of the endogenous luteinizing hormone surge during IVF. Several practical aspects of implementing a GnRH antagonist-based stimulation protocol are described; selection of the correct dose, choosing when to start the antagonist, programming of cycle starts, selection of the appropriate gonadotropins, and triggering of final oocyte maturation are elucidated.
Center of Reproductive Medicine and Infertility, Weill Medical College of Cornell University, New York, NY, USA, davidreichman.md@gmail.com.
David
D
Reichman
Zev
Z
Rosenwaks
D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D007987:Gonadotropin-Releasing Hormone / Q000037:antagonists & inhibitors / Q000378:metabolism*; D006801:Humans; D059471:In Vitro Oocyte Maturation Techniques / Q000379:methods; D007986:Luteinizing Hormone / Q000235:genetics / Q000378:metabolism*; D009865:Oocytes / Q000254:growth & development / Q000378:metabolism; D009866:Oogenesis / Q000235:genetics
D007987:Gonadotropin-Releasing Hormone; D007986:Luteinizing Hormone