The anti-inflammasome effect of lactate and the lactate GPR81-receptor in pancreatic and liver inflammation.
Department of Medicine A, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany. Electronic address: lerch@uni-greifswald.de.
Markus M
MM
Lerch
Division of Gastroenterology, Hepatology and Nutrition, Ohio State University, Columbus, Ohio.
Darwin L
DL
Conwell
Department of Medicine A, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany.
Julia
J
Mayerle
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D056486:Chemical and Drug Induced Liver Injury / Q000517:prevention & control*; D006801:Humans; D007113:Immunity, Innate / Q000187:drug effects*; D058847:Inflammasomes / Q000187:drug effects*; D008099:Liver / Q000187:drug effects*; D008297:Male; D010179:Pancreas / Q000187:drug effects*; D010195:Pancreatitis / Q000517:prevention & control*; D043562:Receptors, G-Protein-Coupled / Q000378:metabolism*; D019354:Sodium Lactate / Q000494:pharmacology*; D051193:Toll-Like Receptors / Q000187:drug effects*
D000893:Anti-Inflammatory Agents; C533610:HCAR1 protein, human; C529424:Hcar1 protein, mouse; D058847:Inflammasomes; D043562:Receptors, G-Protein-Coupled; D051193:Toll-Like Receptors; D019354:Sodium Lactate