[Clinical practice guideline for the diagnosis and treatment of hyperprolactinemia].
BACKGROUND
Hyperprolactinemia is a common finding within clinical practice in both endocrinology and general practice fields, amongst other specialties. The general practitioner and other specialists must know the indications and serum prolactin determination parameters in order to, once detected, derive the patient for a correct assessment and begin treatment.


OBJECTIVE
Formulate a clinical practice guideline evidence-based for the diagnosis and treatment of hyperprolactinemia.


METHODS
It took the participation of eight gynecologists, two pathologists and a pharmacologist in the elaboration of this guideline due their experience and clinical judgement. These recommendations were based upon diagnostic criteria and levels of evidence from treatment guidelines previously established, controlled clinical trials and standardized guides for adolescent and adult population with hyperprolactinemia.


RESULTS
During the conformation of this guideline each specialist reviewed and updated a specific topic and established the evidence existent over different topics according their field of best clinical expertise, being enriched by the opinion of other experts. At the end, all the evidence and decisions taken were unified in the document presented here.


CONCLUSIONS
It is presented the recommendations established by the panel of experts for diagnosis and treatment of patients with high levels of prolactin; also the level of evidence for the diagnosis of hyperprolactinemia, handling drug-induced hyperprolactinemia and prolactinomas in pregnant and non-pregnant patients.
Carlos Gerardo
CG
Salazar-López-Ortiz
José Alberto
JA
Hernández-Bueno
David
D
González-Bárcena
Mireya
M
López-Gamboa
Alma
A
Ortiz-Plata
Hans L
HL
Porias-Cuéllar
J Daniel
JD
Rembao-Bojórquez
Gabriel Alfredo
GA
Sandoval-Huerta
Rosario
R
Tapia-Serrano
Gumersindo Gaspar
GG
Vázquez-Castillo
Victor Saúl
VS
Vital-Reyes
D000293:Adolescent; D000328:Adult; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D006966:Hyperprolactinemia / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D010911:Pituitary Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D011388:Prolactin / Q000378:metabolism; D015175:Prolactinoma / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*
D011388:Prolactin