[Case of drug-induced angioedema (DIAE) on induction of anesthesia with difficult ventilation due to oropharyngeal edema].
A 69-year-old man with a past history of hypertension on angiotensin II receptor blocker (ARB) for three months presented for radical prostatectomy. Immediately after induction of anesthesia with fentanyl and propofol, mask ventilation became difficult, although no significant hemodynamic changes occurred. Fiberoptic examination revealed severe oropharyngeal edema, but, the trachea was successfully intubated. Afterward, the operation proceeded without complications. He stayed in the ICU for 4 days until the trachea was extubated successfully. He was diagnosed with DIAE because of his history of dyspnea with exclusion of other possible pathophysiological conditions.
Tomoaki
T
Urabe
Shin
S
Kawana
Ryosuke
R
Kamimura
Ryo
R
Nishisako
D000368:Aged; D000767:Anesthesia, Epidural; D000768:Anesthesia, General; D000799:Angioedema / Q000139:chemically induced*; D057911:Angiotensin Receptor Antagonists / Q000009:adverse effects*; D004487:Edema / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D007442:Intubation, Intratracheal / Q000379:methods*; D008297:Male; D010608:Pharyngeal Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000601:surgery; D012720:Severity of Illness Index; D013777:Tetrazoles / Q000009:adverse effects*; D014633:Valine / Q000009:adverse effects / Q000031:analogs & derivatives*; D000068756:Valsartan
D057911:Angiotensin Receptor Antagonists; D013777:Tetrazoles; D000068756:Valsartan; D014633:Valine