The cut-off values of anthropometric indices for identifying subjects at risk for metabolic syndrome in Iranian elderly men.
OBJECTIVE
This study aimed to investigate which anthropometric indices could be a better predictor of metabolic syndrome (MetS) and the cut-off points for these surrogates to appropriately differentiate MetS in the Iranian elderly.


METHODS
The present cross-sectional study was conducted on a sample of Isfahan Healthy Heart Program (IHHP). MetS was defined according to Third Adult Treatment Panel (ATPIII). In total, 206 elderly subjects with MetS criteria were selected. Anthropometric indices were measured and plotted using receiver operating characteristic (ROC) curves.


RESULTS
WC followed by WHtR yielded the highest area under the curve (AUC) (0.683; 95% CI 0.606-0.761 and 0.680; 95% CI 0.602-0.758, resp.) for MetS. WC at a cut of 94.5 cm resulted in the highest Youden index with sensitivity 64% and 68% specificity to predict the presence of ≥2 metabolic risk factors. BMI had the lowest sensitivity and specificity for MetS and MetS components. WC has the best ability to detect MetS which followed by WHtR and BMI had a lower discriminating value comparatively.


CONCLUSIONS
WC is the best predictor for predicting the presence of ≥2 metabolic risk factors among Iranian elderly population and the best value of WC is 94.5 cm. This cut-off values of WC should be advocated and used in Iranian men until larger cross-sectional studies show different results.
Metabolic Syndrome Department, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Mojgan
M
Gharipour
Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute (WHO Collaborating Center), Isfahan University of Medical Sciences, Isfahan, Iran.
Masoumeh
M
Sadeghi
Interventional Cardiology Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Minoo
M
Dianatkhah
Hypertension Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Shirin
S
Bidmeshgi
Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Alireza
A
Ahmadi
Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Marzieh
M
Tahri
Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Nizal
N
Sarrafzadegan
D000368:Aged; D000886:Anthropometry; D019540:Area Under Curve; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D006801:Humans; D007492:Iran; D008297:Male; D024821:Metabolic Syndrome / Q000209:etiology*; D009765:Obesity / Q000150:complications*; D056128:Obesity, Abdominal / Q000150:complications; D011237:Predictive Value of Tests; D012372:ROC Curve; D012016:Reference Values; D055105:Waist Circumference; D049629:Waist-Hip Ratio