Different risk factors for candidemia occur for Candida species belonging to the C. parapsilosis complex.
Previous studies have demonstrated reduced virulence in the species that comprise the Candida parapsilosis complex. We investigated a cohort of 93 patients with candidemia caused by this complex. Most infections were caused by C. parapsilosis (80.6%), followed by C. orthopsilosis (18.3%) and C. metapsilosis (1.1%). Renal failure (P < 0.001) and chronic liver diseases (P = 0.019) were more frequently encountered with infections caused by the C. orthopsilosis group, suggesting an association with patients who had a greater state of immune suppression in comparison with infections caused by C. parapsilosis sensu stricto.
Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil.
C C
CC
Constante
A A
AA
Monteiro
S H
SH
Alves
L C
LC
Carneiro
M M
MM
Machado
L C
LC
Severo
S
S
Park
D S
DS
Perlin
A C
AC
Pasqualotto
D002175:Candida / Q000145:classification* / Q000302:isolation & purification*; D058387:Candidemia / Q000150:complications / Q000453:epidemiology* / Q000382:microbiology*; D015331:Cohort Studies; D006801:Humans; D008107:Liver Diseases / Q000453:epidemiology / Q000209:etiology; D015995:Prevalence; D051437:Renal Insufficiency / Q000453:epidemiology / Q000209:etiology; D018570:Risk Assessment; D012307:Risk Factors