Rhinovirus and the developing lung.
Human rhinovirus (HRV) infections are now widely accepted as the commonest cause of acute respiratory illnesses (ARIs) in children. Advanced PCR techniques have enabled HRV infections to be identified as causative agents in most common ARIs in childhood including bronchiolitis, acute asthma, pneumonia and croup. However, the long-term implications of rhinovirus infections are less clear. The aim of this review is to examine the relationship between rhinovirus infections and disorders of the lower airways in childhood.
School of Paediatrics and Child Health, University of Western Australia, Perth, WA, Australia; Respiratory Department, Our Lady's Children's Hospital, Crumlin, Dublin 12, Ireland.
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Cox
School of Paediatrics and Child Health, University of Western Australia, Perth, WA, Australia; Respiratory Medicine, Princess Margaret Hospital for Children, Perth, WA, Australia.
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PN
Le Souëf
D001988:Bronchiolitis / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D003139:Common Cold / Q000150:complications* / Q000503:physiopathology*; D006801:Humans; D007223:Infant; D008168:Lung / Q000254:growth & development*; D010641:Phenotype; D012229:Rhinovirus / Q000145:classification / Q000235:genetics
Rhinovirus; children; respiratory illnesses