[Case of leptomeningeal carcinomatosis with esophageal carcinoma presenting with neurological signs].
A 72-year-old male was admitted because of hearing impairment, blurred vision, right hemifacial numbness, and difficulty walking. Brain magnetic resonance imaging revealed two enhancing lesions with infiltration around the cranial nerves indicating either metastatic brain tumors or meningeal carcinomatosis. Cytological examination of the cerebrospinal fluid revealed malignant cells with keratotic changes. Upper gastrointestinal endoscopy was performed, which revealed type 1 squamous cell carcinoma of the esophagus;this led to the diagnosis of leptomeningeal carcinomatosis. In this report, we present a rare case of esophageal carcinoma accompanied by meningeal carcinomatosis diagnosed on the basis of neurological symptoms.
First Department of Medicine, University of Yamanashi.
Nobutoshi
N
Komatsu
Tatsuya
T
Yamaguchi
Yuya
Y
Tsukui
Hiroshi
H
Hayakawa
Shouji
S
Kobayashi
Makoto
M
Kadokura
Fumitake
F
Amemiya
Kazuyuki
K
Miyata
Hiroyuki
H
Ohtsuka
Nobuyuki
N
Enomoto
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000175:diagnosis / Q000532:radiotherapy; D004938:Esophageal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000532:radiotherapy; D017809:Fatal Outcome; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D055756:Meningeal Carcinomatosis / Q000175:diagnosis / Q000209:etiology* / Q000532:radiotherapy; D009422:Nervous System Diseases / Q000209:etiology*; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed