Seroepidemiology of astrovirus MLB1.
To determine the seroprevalence of astrovirus MLB1 (MLB1), an indirect enzyme-linked immunosorbent assay (ELISA) was established. MLB1 seropositivity was high in children <6 months old, decreased to a nadir at 12 to 23 months old, and increased to 100% by adulthood. MLB1 infection is common, and primary exposure occurs in childhood.
Washington University School of Medicine, St. Louis, Missouri, USA.
Lori R
LR
Holtz
Washington University School of Medicine, St. Louis, Missouri, USA.
Irma K
IK
Bauer
Washington University School of Medicine, St. Louis, Missouri, USA.
Hongbing
H
Jiang
Saint Louis University, St. Louis, Missouri, USA.
Robert
R
Belshe
St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Pamela
P
Freiden
St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Stacey L
SL
Schultz-Cherry
Washington University School of Medicine, St. Louis, Missouri, USA davewang@wustl.edu.
David
D
Wang
D000914:Antibodies, Viral / Q000097:blood*; D019350:Astroviridae Infections / Q000453:epidemiology* / Q000276:immunology*; D002213:Capsid / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D005243:Feces / Q000821:virology; D006801:Humans; D007223:Infant; D001257:Mamastrovirus / Q000145:classification / Q000276:immunology*; D016366:Open Reading Frames / Q000276:immunology; D016036:Seroepidemiologic Studies
D000914:Antibodies, Viral