Alkyl transfer from C-C cleavage: replacing the nitro group of nitro-olefins.
Alkyl substituted Hantzsch esters are rationally used as alkylation reagents to replace the nitro groups of nitro olefins to give excellent yields of trans-olefins. The reaction mechanism is considered to proceed through a free radical mechanism, which is different from the corresponding transfer alkylation of imines.
Natural Products Research Center, Chengdu Institution of Biology, Chinese Academy of Science, Chengdu, Sichuan 610041, China. tangzhuo@cib.ac.cn.
Guangxun
G
Li
Lei
L
Wu
Gang
G
Lv
Hongxin
H
Liu
Qingquan
Q
Fu
Xiaomei
X
Zhang
Zhuo
Z
Tang
D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry*; D005609:Free Radicals / Q000737:chemistry; D015394:Molecular Structure; D009574:Nitro Compounds / Q000737:chemistry*
D000475:Alkenes; D005609:Free Radicals; D009574:Nitro Compounds