Initial and post-treatment total oxidant-antioxidant status and oxidative stress index in male patients with manic episode.
We investigated serum total oxidative and anti-oxidative status in manic patients. Group1 was formed as ECT+antipsychotic, group2 was antipsychotic and healthy volunteers as group3. The anti-oxidative status was significantly lower in group1 than group3. No significant change was found between pre and post-treatment oxidative and anti-oxidative status, whereas significantly increased oxidative stress index has been found in group2. Total anti-oxidative status in manic states seems to be inadequate which remains to be maintained after the treatment.
Department of Psychiatry, Bakırkoy Mental Health Research and Training, State Hospital, Istanbul, Turkey. Electronic address: tevfikkaleli@hotmail.com.
Tevfik
T
Kalelioglu
Department of Psychiatry, Bakırkoy Mental Health Research and Training, State Hospital, Istanbul, Turkey.
Abdullah
A
Genc
Department of Psychiatry, Bakırkoy Mental Health Research and Training, State Hospital, Istanbul, Turkey.
Nesrin
N
Karamustafalioglu
Department of Psychiatry, Bakırkoy Mental Health Research and Training, State Hospital, Istanbul, Turkey.
Akif
A
Tasdemir
Department of Psychiatry, Bakırkoy Mental Health Research and Training, State Hospital, Istanbul, Turkey.
Ferda
F
Can Gungor
Department of Psychiatry, Bakırkoy Mental Health Research and Training, State Hospital, Istanbul, Turkey.
Alparslan
A
Cansiz
Department of Biochemistry, Medical School of Cerrahpasa, Istanbul University, Turkey.
Said
S
Incir
Department of Psychiatry, Bakırkoy Mental Health Research and Training, State Hospital, Istanbul, Turkey.
M
M
Cem Ilnem
Department of Psychiatry, Medical School of Cerrahpasa, Istanbul University, Turkey.
Murat
M
Emul
D000975:Antioxidants; D014150:Antipsychotic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001714:Bipolar Disorder / Q000097:blood* / Q000188:drug therapy / Q000628:therapy; D003987:Dibenzothiazepines / Q000494:pharmacology / Q000627:therapeutic use*; D004565:Electroconvulsive Therapy; D006220:Haloperidol / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D016877:Oxidants / Q000097:blood; D018384:Oxidative Stress / Q000187:drug effects / Q000502:physiology*; D000069348:Quetiapine Fumarate
D000975:Antioxidants; D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D016877:Oxidants; D000069348:Quetiapine Fumarate; D006220:Haloperidol
ECT; Mania; Oxidative stress