Simultaneous microwave extraction and separation of volatile and non-volatile organic compounds of boldo leaves. From lab to industrial scale.
Microwave extraction and separation has been used to increase the concentration of the extract compared to the conventional method with the same solid/liquid ratio, reducing extraction time and separate at the same time Volatile Organic Compounds (VOC) from non-Volatile Organic Compounds (NVOC) of boldo leaves. As preliminary study, a response surface method has been used to optimize the extraction of soluble material and the separation of VOC from the plant in laboratory scale. The results from the statistical analysis revealed that the optimized conditions were: microwave power 200 W, extraction time 56 min and solid liquid ratio of 7.5% of plants in water. Lab scale optimized microwave method is compared to conventional distillation, and requires a power/mass ratio of 0.4 W/g of water engaged. This power/mass ratio is kept in order to upscale from lab to pilot plant.
GREEN Extraction Team, Institut National de Recherche Agronomiques INRA, Unité Mixte de Recherche UMR 408, Avignon University, F-84000 Avignon, France. joel.wajsman@basf.com.
Loïc
L
Petigny
GREEN Extraction Team, Institut National de Recherche Agronomiques INRA, Unité Mixte de Recherche UMR 408, Avignon University, F-84000 Avignon, France. sandrine.perino@univ-avignon.fr.
Sandrine
S
Périno
Milestone srl, Via Fatebenefratelli 1/5, I-26010 Sorisole, Bergamo, Italy. m.minuti@milestonesrl.com.
Matteo
M
Minuti
Milestone srl, Via Fatebenefratelli 1/5, I-26010 Sorisole, Bergamo, Italy. f.visinoni@milestonesrl.com.
Francesco
F
Visinoni
BASF, Beauty Care Solutions France, F-69007 Lyon, France. joel.wajsman@basf.com.
Joël
J
Wajsman
GREEN Extraction Team, Institut National de Recherche Agronomiques INRA, Unité Mixte de Recherche UMR 408, Avignon University, F-84000 Avignon, France. farid.chemat@univ-avignon.fr.
Farid
F
Chemat
D005591:Chemical Fractionation / Q000295:instrumentation*; D004867:Equipment Design; D008401:Gas Chromatography-Mass Spectrometry; D008872:Microwaves; D009822:Oils, Volatile / Q000737:chemistry*; D031611:Peumus / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*; D055549:Volatile Organic Compounds / Q000302:isolation & purification*
D009822:Oils, Volatile; D055549:Volatile Organic Compounds