Eosinophils and cancer.
Eosinophils have long been known to infiltrate tumors, and in most cases, this is associated with an improved prognosis. However, the reasons behind this infiltration and the mechanism of action of the eosinophil have remained elusive. In this article, we explore the biology of eosinophils and examine their function in homeostasis and disease states, specifically focusing on what is currently known about the association of the eosinophil with cancer.
Authors' Affiliation: Cincinnati Children's Hospital Medical Center, Division of Allergy and Immunology, Cincinnati, Ohio.
Benjamin P
BP
Davis
Marc E
ME
Rothenberg
D000818:Animals; D004804:Eosinophils / Q000276:immunology* / Q000378:metabolism / Q000473:pathology*; D006086:Graft vs Host Disease / Q000276:immunology / Q000473:pathology; D006801:Humans; D006967:Hypersensitivity / Q000150:complications; D009369:Neoplasms / Q000150:complications / Q000209:etiology* / Q000473:pathology*