Regulation of gene expression at low temperature: role of cold-inducible promoters.
Psychrophilic micro-organisms are the most dominant flora in cold habitats. Their unique ability to survive and multiply at low temperatures (<5 °C) is based on their ability to modulate the rigidity of the membrane, to transcribe, to translate and to catalyse biochemical reactions at low temperature. A number of genes are known to be upregulated during growth at low temperature and cold-inducible promoters are known to regulate the expression of genes at low temperature. In this review, we attempted to compile promoter sequences of genes that are cold-inducible so as to identify similarities and to compare the distinct features of each type of promoter when microbes are grown in the cold.
Centre of Biotechnology (University of Allahabad), Allahabad, India.
Ashish Kumar
AK
Singh
Centre of Biotechnology (University of Allahabad), Allahabad, India.
Kirti
K
Sad
Centre of Biotechnology (University of Allahabad), Allahabad, India.
Shailendra Kumar
SK
Singh
L. V. Prasad Eye Institute, Hyderabad, India.
Sisinthy
S
Shivaji
D001419:Bacteria / Q000235:genetics*; D001483:Base Sequence; D003080:Cold Temperature; D015964:Gene Expression Regulation, Bacterial / Q000235:genetics*; D008969:Molecular Sequence Data; D011401:Promoter Regions, Genetic / Q000235:genetics*; D015398:Signal Transduction; D037941:Silencer Elements, Transcriptional / Q000235:genetics