A near tetraploid clone in acute myeloid leukemia with CD56 expression.
Acute myeloid leukemia (AML) is a heterogeneous disorder characterized by specific morphology, immunophenotype and genetic rearrangements. Multiple recurrent chromosomal aberrations have been identified by conventional cytogenetic analysis, which are now widely recognized as one of the most important diagnostic and prognostic determinants in AML. Here, we present a case with unusual cytogenetics, which has been described in very few patients.
Department of Laboratory Medicine, Basavatarakam Indo-American Cancer Hospital and Research Institute, Banjara Hills, Hyderabad, Andhra Pradesh, India.
Sandhya Devi
SD
Gundimeda
Faiq
F
Ahmed
Manasi Chetan
MC
Mundada
Senthil Jagannathan
SJ
Rajappa
Sudha S
SS
Murthy
D000328:Adult; D000954:Antigens, Surface / Q000378:metabolism; D019002:CD56 Antigen / Q000235:genetics / Q000378:metabolism*; D015870:Gene Expression; D006801:Humans; D016130:Immunophenotyping; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics* / Q000378:metabolism*; D008297:Male; D057891:Tetraploidy; D028761:Withholding Treatment
D000954:Antigens, Surface; D019002:CD56 Antigen