[Influence of ethyl alcohol on diabetes pathogenesis type].
Relations between metabolism of carbohydrates and ethyl alcohol consumption became a subject of many research because they occur very frequently amongst alcoholics. One of the most often and dangerous effects of abusing ethanol is hypoglycemia. It is caused by hepatic gluconeogenesis disturbed by ethyl alcohol. Chronic result of abusing alcohol is chronic pancreas inflammation (PZT), what causes disorders of exo- and endocrine function of pancreas. Endocrine function is secretion of insulin and the glucagon what regulates metabolism of absorbed compounds. Failure of beta cells of Langerhans islets causes diabetes demanding insulin therapy. The ethanol can cause recurring diabetes resulting from damage of cells of Langerhans islets but can be also the risk factor of diabetes type 2.
Elzbieta
E
Zasimowicz
Blanka
B
Wolszczak
Barbara
B
Zasimowicz
D000428:Alcohol Drinking / Q000009:adverse effects* / Q000378:metabolism; D000437:Alcoholism / Q000150:complications* / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology / Q000378:metabolism; D006801:Humans; D010179:Pancreas / Q000378:metabolism; D010195:Pancreatitis / Q000209:etiology*