Nitrogen-doped carbon dots derived from polyvinyl pyrrolidone and their multicolor cell imaging.
Nitrogen-doped carbon dots (N-CDs) with a high quantum yield of 19.6% were prepared by calcining polyvinyl pyrrolidone (PVP, K-30), and then modified with 4,7,10-trioxa-1,13-tridecanediamine. The as-prepared N-CDs exhibited excitation-dependent and pH-sensitive photoluminescence. Transmission electron microscopy and Raman spectra demonstrated the graphitic structure of the N-CDs. Fourier transform infrared spectroscopy and x-ray diffraction studies revealed successful passivation and the presence of hydrophilic groups on the surface. Importantly, such modified quantum dots acted as good multicolor cell imaging probes due to their excellent fluorescent properties, low cytotoxicity and fine dispersity.
Department of Chemistry, Fudan University, Shanghai 200433, People's Republic of China.
Hui
H
Ding
Peng
P
Zhang
Tian-Yi
TY
Wang
Ji-Lie
JL
Kong
Huan-Ming
HM
Xiong
D002244:Carbon; D006367:HeLa Cells; D006801:Humans; D046529:Microscopy, Electron, Transmission; D008856:Microscopy, Fluorescence; D009584:Nitrogen; D011205:Povidone; D045663:Quantum Dots / Q000737:chemistry* / Q000648:ultrastructure; D017550:Spectroscopy, Fourier Transform Infrared; D013059:Spectrum Analysis, Raman; D014961:X-Ray Diffraction
D002244:Carbon; D011205:Povidone; D009584:Nitrogen