Infertility trial outcomes: healthy moms and babies.
Traditionally, the primary outcome of infertility trials has been a positive pregnancy test or a clinically recognized pregnancy. However, parents desire a healthy baby that grows up to be a healthy adult, rather than a positive pregnancy test. Too often results of infertility trials are lacking in crucial obstetric details. This is problematic because treatments for infertility have the capacity to increase the risk for a variety of adverse obstetric outcomes. This review will outline important obstetric variables that should be included when reporting infertility research. The rationale for including these data, precise definitions of the variables, and cost-effective strategies for obtaining these obstetric details will be highlighted.
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, Utah. Electronic address: bob.silver@hsc.utah.edu.
Robert
R
Silver
D002986:Clinical Trials as Topic / Q000592:standards*; D005260:Female; D006801:Humans; D007223:Infant; D007229:Infant Welfare; D007246:Infertility / Q000453:epidemiology / Q000628:therapy*; D008429:Maternal Welfare; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology / Q000628:therapy; D047928:Premature Birth / Q000453:epidemiology / Q000628:therapy; D016896:Treatment Outcome
Obstetric complications; clinical trials; infertility treatment; pregnancy loss; preterm birth