[Metastatic collecting duct carcinoma with relatively long-term survival treated with sunitinib: a case report].
A 51-year-old man visited our hospital with a chief complaint of left renal mass detected by ultrasonography in another hospital. Enhanced computed tomography (CT) revealed a hypovascular tumor measuring about 9 cm in the left kidney, tumor thrombus in the inferior vena cava and paraaortic lymph nodes metastases. Radical left transperitoneal nephrectomy with removal of the thrombus from the left renal vein were performed. Paraaortic lymph nodes dissection was partially performed because of the solid adhesion to aorta. Histological examination revealed collecting duct carcinoma (CDC). He was treated with systemic chemotherapy (gemcitabine plus nedaplatin) followed by sunitinib. Duration of stable disease after initiation of therapy was seventeen months, and survival after surgery was 31 months. It would be worthwhile to prospectively evaluate the antitumor activity of tyrosine kinase inhibitors against metastatic CDC.
The Department of Urology, Yokohama City Minato Red Cross Hospital.
Teppei
T
Takeshima
The Department of Urology, Yokohama City Minato Red Cross Hospital.
Manami
M
Nakamura
The Department of Urology, Yokohama City Minato Red Cross Hospital.
Zenkichi
Z
Sekiguchi
The Department of Urology, Yokohama City Minato Red Cross Hospital.
Akitoshi
A
Takizawa
The Department of Urology, Yokohama City Minato Red Cross Hospital.
Futoshi
F
Tsuchiya
D000970:Antineoplastic Agents / Q000627:therapeutic use; D002292:Carcinoma, Renal Cell / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007211:Indoles / Q000627:therapeutic use*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D011758:Pyrroles / Q000627:therapeutic use*; D000077210:Sunitinib
D000970:Antineoplastic Agents; D007211:Indoles; D011758:Pyrroles; D000077210:Sunitinib