Hantavirus infection in rodents and haemorrhagic fever with renal syndrome in Shaanxi province, China, 1984-2012.
The transmission of haemorrhagic fever with renal syndrome (HFRS) is deeply influenced by the reservoir and hantavirus prevalence rate. In this study, a surveillance on human HFRS cases, relative rodent abundance, and hantavirus infection prevalence was conducted in Shaanxi province, China, during 1984-2012. A generalized linear model with Poisson-distributed residuals and a log link was used to quantify the relationship between reservoir, virus and HFRS cases. The result indicated that there was a significant association of HFRS incidence with relative rodent density and the prevalence rate. This research provides evidence that the changes of infection prevalence in the reservoir could lead directly to the emergence of a new epidemic. It was concluded that the measurement of a number of these variables could be used in disease surveillance to give useful advance warning of potential disease epidemics.
Shaanxi Provincial Centre for Disease Control and Prevention,Xi'an, Shaanxi,China.
P B
PB
Yu
College of Global Change and Earth System Science,Beijing Normal University,Beijing,China.
H Y
HY
Tian
Xi'an Centre for Disease Control and Prevention,Xi'an, Shaanxi,China.
C F
CF
Ma
Hu County Centre for Disease Control and Prevention of Shaanxi Province,Xi'an, Shaanxi,China.
C A
CA
Ma
Shaanxi Provincial Centre for Disease Control and Prevention,Xi'an, Shaanxi,China.
J
J
Wei
Hu County Centre for Disease Control and Prevention of Shaanxi Province,Xi'an, Shaanxi,China.
X L
XL
Lu
Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine,Beijing Chaoyang Hospital Affiliated to Capital Medical University,Beijing,China.
Z
Z
Wang
School of Environment,Tsinghua University,Beijing,China.
S
S
Zhou
Shaanxi Provincial Centre for Disease Control and Prevention,Xi'an, Shaanxi,China.
S
S
Li
Shaanxi Provincial Centre for Disease Control and Prevention,Xi'an, Shaanxi,China.
J H
JH
Dong
Department of Immunology and Pathogenic Biology, School of Medicine,Xi'an Jiaotong University.
J R
JR
Xu
College of Global Change and Earth System Science,Beijing Normal University,Beijing,China.
B
B
Xu
Shaanxi Provincial Centre for Disease Control and Prevention,Xi'an, Shaanxi,China.
J J
JJ
Wang
D000818:Animals; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D058872:Epidemics; D006476:Orthohantavirus; D018778:Hantavirus Infections / Q000453:epidemiology* / Q000662:veterinary*; D006480:Hemorrhagic Fever with Renal Syndrome / Q000453:epidemiology*; D006801:Humans; D015995:Prevalence; D012377:Rodentia / Q000821:virology*