Primary central nervous system lymphoma in an human immunodeficiency virus-infected patient mimicking bilateral eye sign in brain seen in fluorine-18 fluorodeoxyglucose-positron emission tomography/computed tomography.
Fluorodeoxyglucose-positron emission tomography/computed tomography (FDG PET/CT) has proven useful in the diagnosis, staging, and detection of metastasis and posttreatment monitoring of several malignancies in human immunodeficiency virus (HIV)-infected patients. It also has the ability to make the important distinction between malignancy and infection in the evaluation of central nervous system (CNS) lesions, leading to the initiation of the appropriate treatment and precluding the need for invasive biopsy. We report an interesting case of HIV positive 35-year-old woman presented with headache, disorientation, and decreased level of consciousness. She underwent whole body PET/CT which showed multiple lesions in the cerebrum which mimics bilateral eye in brain. A diagnosis of a primary CNS lymphoma was made and patient was started on chemotherapy.
Department of Nuclear Medicine and Positron Emission Tomography-Computed Tomography, Comprehensive Cancer Care Centre, Kovai Medical Centre and Hospital Limited, Coimbatore, Tamil Nadu, India.
Koramadai Karuppusany
KK
Kamaleshwaran
Department of Hematology, Comprehensive Cancer Care Centre, Kovai Medical Centre and Hospital Limited, Coimbatore, Tamil Nadu, India.
Rajasekar
R
Thirugnanam
Department of Nuclear Medicine and Positron Emission Tomography-Computed Tomography, Comprehensive Cancer Care Centre, Kovai Medical Centre and Hospital Limited, Coimbatore, Tamil Nadu, India.
Deepu
D
Shibu
Department of Nuclear Medicine and Positron Emission Tomography-Computed Tomography, Comprehensive Cancer Care Centre, Kovai Medical Centre and Hospital Limited, Coimbatore, Tamil Nadu, India.
Radhakrishnan Edathurthy
RE
Kalarikal
Department of Nuclear Medicine and Positron Emission Tomography-Computed Tomography, Comprehensive Cancer Care Centre, Kovai Medical Centre and Hospital Limited, Coimbatore, Tamil Nadu, India.
Ajit Sugunan
AS
Shinto
18-F fluorodeoxyglucose-positron emission tomography/computed tomography; HIV positive; bilateral eye sign in brain; primary central nervous system lymphomaw