Traumatized immature teeth treated with 2 protocols of pulp revascularization.
BACKGROUND
Pulp revascularization may be considered a promising alternative for traumatized necrotic immature teeth. The aim of this study was to evaluate traumatized immature teeth treated with 2 protocols of pulp revascularization.


METHODS
Twenty-three teeth of young patients (7-17 years old) with necrotic upper incisors caused by dental trauma were divided into 2 groups; one group was treated with triple antibiotic paste (metronidazole, ciprofloxacin, and minocycline) (TAP) (n = 12), and the other was medicated with combination of calcium hydroxide and 2% chlorhexidine gel (CHP) (n = 11). Patients were treated and followed up for a period from 9-19 months in 2 dental institutions for evaluation of clinical and radiographic data.


RESULTS
Most of the teeth were affected by lateral luxation (47.8%). Clinical evaluation in group TAP showed significant reduction in spontaneous pain (P = .01), pain on horizontal percussion (P = .007), and pain on palpation (P = .03), whereas group CHP showed significant reduction in pain on vertical percussion (P = .03). Crown discoloration was observed significantly more in teeth of group TAP (83.3%) (P < .002). On radiographic exam, periapical repair was found in all TAP-treated teeth (P = .03). Similarly, the same findings were found for all teeth treated with CHP with exception of 1 tooth (P = .21). Apical closure was significantly observed in both groups (P < .05). Increase in root length was demonstrated in 5 teeth (41.7%) and 3 teeth (27.3%) of groups TAP and CHP, respectively. Thickening of lateral dentinal walls was observed in 5 teeth of each group.


CONCLUSIONS
Revascularization outcomes for traumatized patients treated with the tested protocols presented similar clinical and radiographic data. However, TAP caused esthetic problem leading to tooth discoloration, which can be considered a disadvantage when compared with CHP.
Department of Restorative Dentistry, Endodontics Area, State University of Campinas-UNICAMP, Piracicaba, São Paulo, Brazil.
Juliana Yuri
JY
Nagata
Department of Restorative Dentistry, Endodontics Area, State University of Campinas-UNICAMP, Piracicaba, São Paulo, Brazil.
Brenda Paula Figueiredo de Almeida
BP
Gomes
Department of Restorative Dentistry, Endodontics Area, State University of Campinas-UNICAMP, Piracicaba, São Paulo, Brazil.
Thiago Farias
TF
Rocha Lima
Department of Dentistry, Endodontics Area, São Leopoldo Mandic Faculty, Campinas, São Paulo, Brazil.
Lia Saori
LS
Murakami
Department of Dentistry, Endodontics Area, São Leopoldo Mandic Faculty, Campinas, São Paulo, Brazil.
Danielle Elaine
DE
de Faria
Department of Dentistry, São Leopoldo Mandic Faculty, Campinas, São Paulo, Brazil.
Gabriel Rocha
GR
Campos
Department of Restorative Dentistry, Endodontics Area, State University of Campinas-UNICAMP, Piracicaba, São Paulo, Brazil.
Francisco José
FJ
de Souza-Filho
Department of Restorative Dentistry, Endodontics Area, State University of Campinas-UNICAMP, Piracicaba, São Paulo, Brazil. Electronic address: ajsoares.endo@uol.com.br.
Adriana de Jesus
Ade J
Soares
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D056624:Apexification / Q000379:methods; D002126:Calcium Hydroxide / Q000627:therapeutic use; D002648:Child; D002710:Chlorhexidine / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use; D003786:Dental Pulp Cavity / Q000187:drug effects; D003790:Dental Pulp Necrosis / Q000628:therapy*; D003804:Dentin / Q000187:drug effects; D005500:Follow-Up Studies; D006801:Humans; D007180:Incisor / Q000293:injuries*; D008795:Metronidazole / Q000627:therapeutic use; D008911:Minocycline / Q000627:therapeutic use; D010486:Periapical Tissue / Q000000981:diagnostic imaging; D011446:Prospective Studies; D016300:Radiography, Bitewing; D012388:Root Canal Irrigants / Q000627:therapeutic use; D012390:Root Canal Therapy / Q000379:methods*; D019227:Tooth Apex / Q000187:drug effects; D014084:Tooth Avulsion / Q000150:complications; D014075:Tooth Discoloration / Q000139:chemically induced; D014098:Toothache / Q000517:prevention & control
D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D012388:Root Canal Irrigants; D008795:Metronidazole; D002939:Ciprofloxacin; D008911:Minocycline; D002126:Calcium Hydroxide; D002710:Chlorhexidine
Calcium hydroxide; intracanal medication; pulp revascularization; triple antibiotic paste