Repeated radiofrequency ablation of atrial tachycardia in restrictive cardiomyopathy secondary to myofibrillar myopathy.
Myofibrillar myopathy is characterized by nonhyaline and hyaline lesions due to mutations in nuclear genes encoding for extra-myofibrillar or myofibrillar proteins. Cardiac involvement in myofibrillar myopathy may be phenotypically expressed as dilated, hypertrophic, or restrictive cardiomyopathy. Radiofrequency ablation of atrial fibrillation and flutter has so far not been reported in myofibrillar myopathy. We report the case of a young female with myofibrillar myopathy and deteriorating heart failure due to restrictive cardiomyopathy and recurrent atrial fibrillation and atrial tachycardias intolerant to pharmacotherapy. Cardiac arrhythmias were successfully treated with repeat radiofrequency ablations and resulted in regression of heart failure, thus postponing the necessity for cardiac transplantation.
Krankenanstalt Rudolfstiftung, Wien, Austria.
Claudia
C
Stöllberger
Krankenanstalt Rudolfstiftung, Wien, Austria.
Edmund
E
Gatterer
Krankenanstalt Rudolfstiftung, Wien, Austria.
Josef
J
Finsterer
Asklepios-Klinik St. Georg, Department of Cardiology, Hamburg, Germany.
Karl-Heinz
KH
Kuck
Asklepios-Klinik St. Georg, Department of Cardiology, Hamburg, Germany.
Roland Richard
RR
Tilz
D001281:Atrial Fibrillation / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D002313:Cardiomyopathy, Restrictive / Q000175:diagnosis / Q000209:etiology*; D017115:Catheter Ablation; D022062:Electrophysiologic Techniques, Cardiac; D005260:Female; D006333:Heart Failure / Q000209:etiology; D006801:Humans; D020914:Myopathies, Structural, Congenital / Q000150:complications / Q000175:diagnosis; D012008:Recurrence; D012086:Reoperation; D013617:Tachycardia, Supraventricular / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult
atrial fibrillation; atrial tachycardia; heart failure; myopathy; radiofrequency ablation; restrictive cardiomyopathy