Thymine vanadyl(II) compound as a diabetic drug model: chemical spectroscopic and antimicrobial assessments.
The aim of this study was to synthesize a novel bifunctionalized thymine vanadyl(II) compound. The solid vanadyl(II) compound has been characterized by elemental analyses (CHN), Raman laser, infrared spectra, molar conductivity, electronic spectra, thermogravimetric analyses (TGA), scanning electron microscopy (SEM) and X-ray powder diffraction (XRD) studies. Electronic and magnetic measurements have confirmed that the speculated geometry of vanadyl(II) compound is square pyramidal geometry. The microbial test was performed for the vanadyl complex against some kinds of bacteria and fungi. The results suggested that [VO(Thy)2] adduct has an anti-diabetic profile.
Department of Chemistry, Faculty of Science, Zagazig University, Egypt; Faculty of Applied Medical Science, Al Jouf University-Al Qurayate, Saudi Arabia.
Mohamed Y
MY
El-Sayed
Chemistry Department, Faculty of Science, Taif University, P.O. Box 888, Al-Hawiah, Taif 21974, Saudi Arabia; Department of Chemistry, Faculty of Science, Port Said University, Port Said, Egypt. Electronic address: msrefat@yahoo.com.
Moamen S
MS
Refat
D000890:Anti-Infective Agents / Q000737:chemistry; D004581:Electronics; D007004:Hypoglycemic Agents / Q000737:chemistry*; D007477:Ions / Q000737:chemistry; D007700:Kinetics; D008024:Ligands; D008280:Magnetics; D008670:Metals; D008826:Microbial Sensitivity Tests; D008855:Microscopy, Electron, Scanning; D008956:Models, Chemical; D013053:Spectrophotometry; D013059:Spectrum Analysis, Raman; D013696:Temperature; D013818:Thermogravimetry; D013941:Thymine / Q000737:chemistry*; D014638:Vanadates / Q000737:chemistry*; D014961:X-Ray Diffraction
D000890:Anti-Infective Agents; D007004:Hypoglycemic Agents; D007477:Ions; D008024:Ligands; D008670:Metals; D014638:Vanadates; D013941:Thymine
Biological evaluation; Spectroscopic studies; Thymine; Vanadyl sulfate