Interactions of quantum dots with donor blood erythrocytes in vitro.
The effects of quantum dots CdSe/ZnS-mercaptopropionic acid, (CdSe/CdZnS)ZnS-polyT, and CdSeCdSZnS/polyT/SiO2-NH2 on human erythrocytes were studied. The nanomaterials reduced signifi cantly the erythrocyte sedimentation rate and modified the erythrocyte membrane resistance to induced (acid and hypo-osmotic) hemolysis. Evaluation of the erythrocyte morphology by atomic force microscopy in the control and after exposure to quantum dots showed significant differences in erythrocyte size and changes in their morphology as a result of exposure to the nanomaterials.
Engineering Physicochemical Faculty, Nizhny Novgorod State Technological University, Nizhny Novgorod, Russia, pleskova@mail.ru.
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SN
Pleskova
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EE
Pudovkina
E R
ER
Mikheeva
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EN
Gorshkova
D000328:Adult; D001782:Blood Donors; D004912:Erythrocytes; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D018625:Microscopy, Atomic Force; D045663:Quantum Dots; D055815:Young Adult