De novo Stage IV breast cancer: breast conserving resection of the primary tumor?
Multiple retrospective reviews completed over the past decade suggest a survival advantage with resection of the intact primary tumor in women with metastatic breast cancer. However, these reviews are not without bias, and recently completed randomized trials do not support a significant survival benefit, although local control benefits may exist. Completion of ongoing trials is needed to reach a definitive conclusion regarding the merit of primary tumor resection for local control and survival.
Professor of Surgery & Bluhm Family Professor of Cancer Research, Feinberg School of Medicine of Northwestern University, Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois.
Seema Ahsan
SA
Khan
D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D015412:Mastectomy, Segmental; D009367:Neoplasm Staging; D011379:Prognosis
breast cancer; breast conserving surgery; local therapy; metastatic; primary tumor