Bilateral dexamethasone intravitreal implant in a young patient with Vogt-Koyanagi-Harada disease and refractory uveitis.
Vogt-Koyanagi-Harada disease (VKHD) is a multisystemic disorder characterized by granulomatous panuveitis with exudative retinal detachments, often associated with neurologic and cutaneous manifestations. Therapy relies mainly on the use of corticosteroids, administrated as oral or intravenous high-dose pulses, and immunosuppressants. However, since macular edema and retinal detachment can often be refractory to systemic therapies, intravitreal triamcinolone acetate has been used successfully. Herein, we report the first case of refractory bilateral panuveitis in a young patient with VKHD successfully treated with dexamethasone intravitreal implant.
Ophthalmology and Neurosurgery Department, University of Siena, Siena, Italy.
Maria Eugenia
ME
Latronico
Donato
D
Rigante
Francesco
F
Caso
Luca
L
Cantarini
Luisa
L
Costa
Laura
L
Nieves-Martín
Claudio
C
Traversi
Rossella
R
Franceschini
D000293:Adolescent; D003907:Dexamethasone / Q000008:administration & dosage*; D004343:Drug Implants; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D015864:Panuveitis / Q000150:complications / Q000188:drug therapy*; D012163:Retinal Detachment / Q000209:etiology / Q000473:pathology*; D041623:Tomography, Optical Coherence; D014607:Uveomeningoencephalitic Syndrome / Q000150:complications / Q000188:drug therapy*; D014822:Vitreous Body
D004343:Drug Implants; D005938:Glucocorticoids; D003907:Dexamethasone