[Resistant arterial hypertension in Primary Care patients in Spain. PRESCAP Study 2010].
OBJECTIVE
To determine the prevalence and clinical and epidemiological characteristics of Primary Care patients with resistant hypertension (RHT) in Spain.


METHODS
A cross-sectional multicenter study was conducted on hypertensive patients aged 18 or over and seen in a Primary Care clinic. RHT was considered as the presence of uncontrolled blood pressure in patients treated with at least 3 drugs, one of which is a diuretic.


RESULTS
Of the 12,961 hypertensive patients in the PRESCAP 2010 study, 962 (7.4%) fulfilled criteria for RHT, of whom 51% were women, and with a mean age (SD) 68.8 [11.4] years. Patients with RHT were older (68.80 [10.69] years vs. 66.06 [11.44] years, P<.001), had a higher prevalence of obesity (55.2 vs. 38.6%, P<.001), a higher waist circumference (103.90 [13.89] vs. 99.32 [13.69] cm, P<.001), and a higher prevalence of DM (48.3 vs. 29.5%, P<.001). The prevalence of target organ damage (73.0 vs. 61.4%, P<.001) and cardiovascular disease (46.7 vs. 26.8%, P<.001) were higher in patients with resistant hypertension. The multivariate analysis showed that the variables associated with resistant hypertension were the presence of cardiovascular disease, diabetes mellitus, sedentary life style, microalbuminuria, body mass index, duration of AHT, and triglycerides.


CONCLUSIONS
The prevalence of RHT in Primary Care patients is related to inappropriate lifestyles, the presence of target organ damage, and cardiovascular disease.
Centro de Salud de Porto do Son, Porto do Son, A Coruña, España. Electronic address: scinzas@semergen.es.
S
S
Cinza-Sanjurjo
Centro de Salud de Sillería, Toledo, España.
F J
FJ
Alonso-Moreno
Centro de Salud de Vallobín-La Florida, Oviedo, España.
M Á
MÁ
Prieto-Díaz
Centro de Salud Casas Ibáñez, Albacete, España.
J A
JA
Divisón-Garrote
Centro de Salud Puebla de Montalbán, La Puebla de Montalbán, Toledo, España.
G C
GC
Rodríguez-Roca
Centro de Salud Ingeniero Joaquín Benlloch, Valencia, España.
J L
JL
Llisterri-Caro
D000367:Age Factors; D000368:Aged; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects*; D002318:Cardiovascular Diseases / Q000150:complications / Q000453:epidemiology; D003430:Cross-Sectional Studies; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D015995:Prevalence; D011320:Primary Health Care; D012307:Risk Factors; D057185:Sedentary Behavior; D013030:Spain / Q000453:epidemiology
D000959:Antihypertensive Agents
Hipertensión resistente; Predictores; Predictors; Prevalence; Prevalencia; Resistant hypertension