MR imaging of Ménière's disease after combined intratympanic and intravenous injection of gadolinium using HYDROPS2.
Endolymphatic hydrops (EH) in Ménière's disease is currently evaluated by 3-dimensional (3D)-real inversion recovery (IR) sequence after intratympanic (IT) administration of gadolinium (Gd) or by heavily T2-weighted (hT2W)-3D-fluid-attenuated IR (FLAIR) sequence after intravenous (IV) injection of Gd. Unilateral IT injection is usually performed. We employed a method in which we simultaneously administered contrast into one ear intravenously (IV side) and into the other ear both intravenously and intratympanically (IT + IV side) to evaluate EH in 10 patients with Ménière's disease. We then compared a HYDROPS2 image obtained by subtracting magnetic resonance cisternography from hT2W-3D-FLAIR with an image obtained by 3D-real IR and found that we could evaluate EH in all ears on the HYDROPS2 image but only in the IT + IV side on the 3D-real IR image.
Department of Radiology, Nagoya University Graduate School of Medicine.
Shinji
S
Naganawa
Masahiro
M
Yamazaki
Hisashi
H
Kawai
Kiminori
K
Bokura
Tatsuo
T
Iida
Michihiko
M
Sone
Tsutomu
T
Nakashima
D000328:Adult; D000368:Aged; D005260:Female; D019786:Gadolinium DTPA / Q000008:administration & dosage*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional; D007267:Injections; D015552:Injections, Intralesional; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008575:Meniere Disease / Q000473:pathology*; D008875:Middle Aged; D013382:Subtraction Technique
C064925:gadodiamide; D019786:Gadolinium DTPA