Does discharge hemoglobin affect medium-term survival after coronary bypass?
BACKGROUND
the effect of discharge hemoglobin on survival of patients undergoing isolated coronary artery bypass grafting is unknown. Blood transfusion frequently confounds the issue.


METHODS
4682 consecutive patients undergoing isolated coronary artery bypass were studied. Univariate and multivariate analyses were performed to identify whether discharge hemoglobin was an independent risk factor determining survival after isolated coronary artery bypass. The analysis was complemented with a neuronal network.


RESULTS
univariate analysis identified discharge hemoglobin (p = 0.01) and blood transfusion (p < 0.0001) as significant factors affecting survival. Multivariate analysis identified age (p < 0.0001) ejection fraction (p < 0.0001), dialysis (p < 0.0001), peripheral vascular disease (p = 0.001), preoperative hemoglobin (p = 0.01), and blood transfusion (p = 0.0002) as significant factors determining survival. Neuronal network analysis confirmed the lack of importance of hemoglobin on discharge as a factor determining survival.


CONCLUSIONS
the discharge hemoglobin level does not affect medium-term survival.
Liverpool Heart and Chest Hospital, Liverpool, UK.
Michael
M
Poullis
D000368:Aged; D000740:Anemia / Q000097:blood* / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D015415:Biomarkers / Q000097:blood; D001803:Blood Transfusion / Q000401:mortality; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000401:mortality*; D005260:Female; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016571:Neural Networks, Computer; D010351:Patient Discharge; D016016:Proportional Hazards Models; D012307:Risk Factors; D015996:Survival Rate; D013997:Time Factors; D016896:Treatment Outcome
D015415:Biomarkers; D006454:Hemoglobins
Anemia; Blood transfusion; Coronary artery bypass; Risk factors; Survival rate