Success in pregnancy through intrauterine insemination at first cycle in 300 infertile couples: an analysis.
OBJECTIVE
The aim of this article was to determine digital levels of the association of factors of pregnancy success after the first cycle of intrauterine insemination (IUI) with 300 infertile couples.


METHODS
The IUI procedure was followed at 36 h after triggering the ovulation, if at least one follicle measured >15 mm. Endometrium thickness (ET) and serum luteinizing hormone (LH) levels were measured at day 10 for each patient. The post-wash total motile fraction (TMF) of semen of the partner of each patient was also evaluated. The principal component analysis (PCA) was done with the data to quantify the associations of related factors.


RESULTS
The clinical pregnancy rate of first cycle IUI attempts was 17.3 %, observed in females, aged 20-39 years and men with TMF >5 million spermatozoa. The ovarian stimulation enabled the development of follicles measuring >16 mm, with LH levels <10 mIU/L and ET >5 mm for success. The PCA revealed that with the female-age parameter, three factors, NF, ET, and LH were related in the component 1; similarly, NF, LH, and RFS were related in component 2; age, NF, ET, LH, LFS, and TMF were related in component 3; and NF, ET, LH, RFS, and LFS in component 4 were related, i.e., the best correlation.


CONCLUSIONS
Associated principal determinative factors, LH, female-age, NF and LFS values were highly significant, but the factors, ET, RFS and TMF were statistically insignificant for success through IUI in pregnancy.
Infertility Unit, Department of Obstetrics and Gynaecology, Institute of Medical Sciences & Sum Hospital, Siksha 'O' Anusandhan University, Kalinga Nagar, Bhubaneswar, 751003 Odisha India.
Babita
B
Panda
Infertility Unit, Department of Obstetrics and Gynaecology, Institute of Medical Sciences & Sum Hospital, Siksha 'O' Anusandhan University, Kalinga Nagar, Bhubaneswar, 751003 Odisha India.
Lita
L
Mohapatra
Central Research Laboratory, Institute of Medical Sciences & Sum Hospital, Siksha 'O' Anusandhan University, K-8 Kalinga Nagar, Bhubaneswar, 751003 Odisha India.
Mahesh C
MC
Sahu
Central Research Laboratory, Institute of Medical Sciences & Sum Hospital, Siksha 'O' Anusandhan University, K-8 Kalinga Nagar, Bhubaneswar, 751003 Odisha India.
Rabindra N
RN
Padhy
Endometrium thickness; Fallopian tube; Intrauterine insemination; Luteinizing hormone; Number of follicles; Total motile fraction of semen