Ultrastructural correlates of antidiuretic response of rat kidney.
We studied ultrastructural features of epithelial cells of the inner medullary collecting tubules in Brattleboro and Wistar under the action of desmopressin (dDAVP, 5 μg/100 g body weight for 2 days). Intracellular reorganization of transepithelial barrier for osmotic water transport depended on the capacity of rats to the synthesis of endogenous vasopressin.
Novosibirsk National Research State University, Novosibirsk, Russia.
A V
AV
Babina
V A
VA
Lavrinenko
D000818:Animals; D050034:Antidiuretic Agents / Q000494:pharmacology*; D022163:Clathrin-Coated Vesicles / Q000187:drug effects / Q000378:metabolism / Q000648:ultrastructure; D003894:Deamino Arginine Vasopressin / Q000494:pharmacology*; D004847:Epithelial Cells / Q000187:drug effects / Q000648:ultrastructure; D007685:Kidney Tubules, Collecting / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D015388:Organelles / Q000187:drug effects / Q000648:ultrastructure; D011910:Rats, Brattleboro; D017208:Rats, Wistar; D014667:Vasopressins / Q000096:biosynthesis
D050034:Antidiuretic Agents; D014667:Vasopressins; D003894:Deamino Arginine Vasopressin