Saliva versus peri-implant inflammation: quantification of IL-1β in partially and totally edentulous patients.
The aim of this study was to investigate the potential use of salivary IL1β in early-stage diagnostics of peri-implant inflammation in partially and totally edentulous patients rehabilitated with dental implants. Patients were classified according to peri-implant probing depth and bleeding upon probing in groups of healthy individuals or in groups of individuals with peri-implant inflammation. Data on plaque index, clinical attachment loss, suppuration, and mobility were also assessed. Saliva was collected without stimulation, and the levels of IL-1β were determined by ELISA. Healthy groups demonstrated significantly lower levels of IL-1β compared with the inflammation groups. No difference in IL-1β levels was observed between partially edentulous or totally edentulous patients. Salivary IL-1β may be useful for the diagnosis and monitoring of early peri-implant inflammation, particularly in edentulous patients.
1 School of Dentistry, Universidade Federal Uberlândia, Uberlândia, Minas Gerais, Brazil.
Flaviana Soares
FS
Rocha
Rainde Naiara Rezende
RN
Jesus
Fabiana Maria Soares
FM
Rocha
Camilla Cristhian Gomes
CC
Moura
Darceny
D
Zanetta-Barbosa
D015921:Dental Implants; D003774:Dental Plaque Index; D005260:Female; D005884:Gingival Hemorrhage / Q000145:classification; D006801:Humans; D053583:Interleukin-1beta / Q000032:analysis*; D007576:Jaw, Edentulous, Partially / Q000276:immunology / Q000534:rehabilitation*; D008297:Male; D009066:Mouth, Edentulous / Q000276:immunology / Q000534:rehabilitation*; D016348:Osseointegration / Q000502:physiology; D017622:Periodontal Attachment Loss / Q000145:classification; D010514:Periodontal Pocket / Q000145:classification; D012463:Saliva / Q000276:immunology*; D012471:Salivary Proteins and Peptides / Q000032:analysis*; D013280:Stomatitis / Q000175:diagnosis* / Q000276:immunology; D013492:Suppuration
D015921:Dental Implants; D053583:Interleukin-1beta; D012471:Salivary Proteins and Peptides