High-calorie diet as a factor of prediabetes development in rats.
We studied the key parameters of the development of prediabetic state in rats maintained on a high-calorie diet. It was found that long-term feeding a high-calorie diet increased blood concentration of glucose, glycosylated hemoglobin, and insulin and reduced the rate of glucose uptake in comparison with rats receiving standard ration.
Education-Scientific Center Institute of Biology, T. Shevchenko Kiev National University, Kyiv, Ukraine, Taras.karpovets@gmail.com.
T P
TP
Karpovets
V V
VV
Konopelnyuk
T I
TI
Galenova
A N
AN
Savchuk
L I
LI
Ostapchenko
D000818:Animals; D021461:Animals, Outbred Strains; D001786:Blood Glucose; D004032:Diet / Q000009:adverse effects*; D002149:Energy Intake; D005260:Female; D007333:Insulin Resistance; D011236:Prediabetic State / Q000097:blood / Q000209:etiology*; D051381:Rats
D001786:Blood Glucose