Pilot survey of hen eggs consumed in the metropolitan area of Rio de Janeiro, Brazil, for polyether ionophores, macrolides and lincosamides residues.
A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method, which has recently been developed and validated, was used for the identification and quantification of polyether ionophore, macrolide and lincosamide residues in commercial eggs sold in the metropolitan area of Rio de Janeiro, Brazil. The method was applied to 100 samples and the results showed a high incidence of polyether ionophore residues (25%). Salinomycin was detected in 21% of samples, but only two non-compliant results (5.3 and 53 µg kg(-1)) were found if maximum limits (tolerances) established by European Union were adopted in Brazil and if a method decision limit (CCα) of 3.4 µg kg(-1) was considered. In 8% of analyzed samples, more than one studied coccidiostat was found. The lincosamide, lincomycin, and the macrolide, tylosin, were detected at trace levels in 4 and 1% of the samples, respectively. Lasalocid, clarithromycin and erythromycin were not found.
a National Institute for Quality Control in Health/Oswaldo Cruz Foundation (INCQS/FIOCRUZ) , Av. Brasil 4365 , Rio de Janeiro , RJ , Brazil.
Bernardete Ferraz
BF
Spisso
Mararlene Ulberg
MU
Pereira
Rosana Gomes
RG
Ferreira
Mychelle Alves
MA
Monteiro
Rafaela Pinto
RP
da Costa
Tatiana Ávila
TÁ
Cruz
Armi Wanderley
AW
da Nóbrega
D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis; D001938:Brazil; D002645:Chickens; D002851:Chromatography, High Pressure Liquid; D002853:Chromatography, Liquid / Q000379:methods; D003049:Coccidiostats / Q000032:analysis; D004531:Eggs / Q000032:analysis*; D004987:Ethers / Q000032:analysis*; D005062:European Union; D005506:Food Contamination / Q000032:analysis; D006801:Humans; D007476:Ionophores / Q000032:analysis*; D055231:Lincosamides / Q000032:analysis*; D018942:Macrolides / Q000032:analysis*; D008452:Maximum Allowable Concentration; D010573:Pesticide Residues / Q000032:analysis*; D053719:Tandem Mass Spectrometry / Q000379:methods
D000900:Anti-Bacterial Agents; D003049:Coccidiostats; D004987:Ethers; D007476:Ionophores; D055231:Lincosamides; D018942:Macrolides; D010573:Pesticide Residues
eggs; veterinary drug residues, antibiotics, tylosin