Prostate biopsy volume predicts final tumor volume.
OBJECTIVE
To assess the ability of prostate biopsy volume to effectively predict actual tumor volume, and whether increasing the number of prostate biopsy cores improves the ability to forecast actual tumor volume.


METHODS
765 patients who underwent robotic radical prostatectomy (2009-2010) were identified. Of these, 663 had complete demographics, biopsy, and final pathology data available. The number ofbiopsy samples, biopsy tumor volume, and actual tumor volume were calculated from pathology reports.


RESULTS
Data from 663 radical prostatectomy specimens indicated a positive linearrelationship between biopsy tumor volume and actual tumor volume (R=0.524, P< 0.0001). The number ofbiopsy samples collected (i.e., < or =6, 7-8, 9-10, 11-12, 13-14, or > or =15) did not affect the ability of biopsy tumor volume to predict final tumor volume.


CONCLUSIONS
The routine collection of biopsy tumor volume may prove useful in predicting actual tumor volume and the construction of more effective preoperative nomograms.
Michael E
ME
Zavaski
Adam
A
Korus
Ilene
I
Staff
Alison
A
Champagne
Jamie
J
Fish-Furhman
Joseph
J
Tortora
Anoop
A
Meraney
Stuart
S
Kesler
Joseph
J
Wagner
D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D001707:Biopsy, Needle; D006801:Humans; D008297:Male; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery; D012189:Retrospective Studies; D012371:Robotics; D047368:Tumor Burden; D018084:Ultrasonography, Interventional