Synthesis of Calocybe indica var. APK2 polysaccharide repeating unit.
The first total synthesis of p-methoxyphenyl α-l-fucopyranosyl-(1→6)-α-d-galactopyranosyl-(1→4)-β-d-glucopyranosyl-(1→6)-β-d-glucopyranosyl-(1→6)-β-d-glucopyranoside (2) was achieved starting from five monosaccharide building blocks. This structure represents the repeating unit of the polysaccharide isolated from edible mushroom Calocybe indica var. APK2, and was synthesized in high overall yield via a convergent '3+2' glycosylation strategy.
College of Chemistry and Life Sciences, Zhejiang Normal University, Jinhua 321004, China.
Lei
L
Zhang
College of Chemistry and Life Sciences, Zhejiang Normal University, Jinhua 321004, China; Centre for Synthesis and Chemical Biology, UCD School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland. Electronic address: Xiangming.Zhu@ucd.ie.
Xiangming
X
Zhu
D000363:Agaricales / Q000737:chemistry*; D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D006031:Glycosylation; D008969:Molecular Sequence Data; D011134:Polysaccharides / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification
D011134:Polysaccharides
Glycosidation; Mushroom polysaccharide; Repeating unit; Synthesis