Diabetic kidney disease: a clinical update from Kidney Disease: Improving Global Outcomes.
The incidence and prevalence of diabetes mellitus (DM) continue to grow markedly throughout the world, due primarily to the increase in type 2 DM (T2DM). Although improvements in DM and hypertension management have reduced the proportion of diabetic individuals who develop chronic kidney disease (CKD) and progress to end-stage renal disease (ESRD), the sheer increase in people developing DM will have a major impact on dialysis and transplant needs. This KDIGO conference addressed a number of controversial areas in the management of DM patients with CKD, including aspects of screening for CKD with measurements of albuminuria and estimated glomerular filtration rate (eGFR); defining treatment outcomes; glycemic management in both those developing CKD and those with ESRD; hypertension goals and management, including blockers of the renin-angiotensin-aldosterone system; and lipid management.
Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Mark E
ME
Molitch
Institute of Metabolic Science, Addenbrooke's Hospitals, Cambridge, UK.
Amanda I
AI
Adler
Aarhus University, Aarhus C, Denmark.
Allan
A
Flyvbjerg
National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA.
Robert G
RG
Nelson
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, People's Republic of China.
Wing-Yee
WY
So
University Hospital of Würzburg, Würzburg, Germany.
Christoph
C
Wanner
Hennepin County Medical Center, Minneapolis, Minnesota, USA.
Bertram L
BL
Kasiske
University College London, London, UK.
David C
DC
Wheeler
University Medical Center Groningen, Groningen, The Netherlands.
Dick
D
de Zeeuw
Aarhus University Hospital and Aarhus University, Aarhus, Denmark.
Carl E
CE
Mogensen
D000419:Albuminuria / Q000209:etiology; D003928:Diabetic Nephropathies / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D018450:Disease Progression; D006801:Humans; D006943:Hyperglycemia / Q000209:etiology; D006973:Hypertension / Q000209:etiology