A systematic review of distraction osteogenesis in hand surgery: what are the benefits, complication rates, and duration of treatment?
BACKGROUND
This work analyzes the utility of distraction osteogenesis as a surgical option for the management of acquired and traumatic hand deformities through a systematic review of the published literature.


METHODS
A PubMed search for articles reporting results of distraction osteogenesis in the hand was performed. Data collected included age, sex, cause, bone distracted, latency period, distraction rate, consolidation period, treatment time, length gained, and complications. Proportion data variables were compared using the chi-square test. A meta-analysis was also performed to assess the size effect of variables on complication development.


RESULTS
Thirty articles (424 distractions) met inclusion criteria. The average length gained from distraction was 2.2 cm; the average total treatment time was 116 days; the average complication rate was 26.4 percent. Proportion analysis, including all articles, showed that congenital cause had significantly fewer complications compared with traumatic cause (p = 0.0129). A lower complication rate in pediatric patients compared with adults approached but did not reach significance (p = 0.0507). Studies that underwent meta-analysis, including only articles comparing both variables of interest, were homogeneous (I < 25) and without publication bias (Kendall's tau p > 0.05 and symmetric funnel plot). None of the variables analyzed by meta-analysis had a significant odds ratio for complication development (p > 0.05).


CONCLUSIONS
Despite distinct advantages, distraction osteogenesis is associated with a long duration of treatment and high complication rates, particularly in adults and in posttraumatic reconstruction.


METHODS
Therapeutic, IV.
Madison, Wis. From the Division of Plastic and Reconstructive Surgery, University of Wisconsin Hospital and Clinics.
Steve J
SJ
Kempton
James E
JE
McCarthy
Ahmed M
AM
Afifi
D006227:Hand Deformities, Acquired / Q000601:surgery*; D006801:Humans; D019857:Osteogenesis, Distraction / Q000009:adverse effects* / Q000379:methods*; D011183:Postoperative Complications / Q000209:etiology*; D016896:Treatment Outcome