Conformational preferences of chiral acyclic homooligomeric β(2,2)-peptides.
α-Methylisoserine, a chiral acyclic quaternary β-amino acid, has been used to mimic secondary structures, when it is incorporated in a homogeneous β(2,2)-dipeptide. In particular, the observed folded conformations in aqueous solution can be regarded as mimics of β-turn.
Fernando
F
Rodriguez
Francisco
F
Corzana
Alberto
A
Avenoza
Jesus Hector
JH
Busto
Jesus Manuel
JM
Peregrina
Departamento de Quimica, Universidad de La Rioja, Centro de Investigacion en Sintesis Quimica, C/ Madre de Dios, 51. 26006 Logrono (La Rioja). Spain. francisco.corzana@unirioja.es.
Maria Del Mar
Mdel M
Zurbano
D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D056004:Molecular Dynamics Simulation; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry*; D017510:Protein Folding; D012694:Serine / Q000031:analogs & derivatives* / Q000737:chemistry
D010455:Peptides; D012694:Serine; C072421:isoserine