Extended-spectrum β-lactamase-producing Escherichia coli isolation among older adults: epidemiology and outcomes.
Clinical outcomes of older and younger adults with extended-spectrum β-lactamase-producing Escherichia coli isolation were compared. Two hundred thirty-two older adults (aged ≥65 years), and 145 younger adults with infection were identified between February 2010 and July 2011. After controlling for the propensity score and receipt of effective therapy, older adults were not at increased risk for adverse outcomes.
Division of Infectious Diseases, Wayne State University, Detroit Medical Center, Detroit, MI.
Sameen
S
Farooq
Division of Infectious Diseases, Wayne State University, Detroit Medical Center, Detroit, MI; Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan. Electronic address: kayokohayakawa@gmail.com.
Kayoko
K
Hayakawa
Division of Infectious Diseases, Wayne State University, Detroit Medical Center, Detroit, MI.
Dror
D
Marchaim
Pharmacy Services, Detroit Medical Center, Detroit, MI.
Jason M
JM
Pogue
Division of Infectious Diseases, Wayne State University, Detroit Medical Center, Detroit, MI.
Keith S
KS
Kaye
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004926:Escherichia coli / Q000201:enzymology* / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000188:drug therapy* / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D017211:Treatment Failure; D055815:Young Adult; D001618:beta-Lactamases / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D001618:beta-Lactamases
Elderly adults; Gram-negative; Multidrug resistant