Prognostic utility of coronary computed tomographic angiography: a 5-year follow-up in type 2 diabetes patients with suspected coronary artery disease.
OBJECTIVE
To analyze the predictive value of coronary computed tomography angiography on acute coronary artery events in patients with type 2 diabetes.


METHODS
Coronary computed tomography angiography was performed in 250 type 2 diabetic patients. After a follow-up for 5 years, 145 patients were excluded as they did not have any coronary events. The remaining 95 patients were divided into study group and control group. According to their density and shape, the coronary artery plaques were classified into 3 types and 4 types, respectively.


RESULTS
There is no statistically significant difference in the degree of stenosis between two groups. The proportion of calcified plaques in the study group was lower than in the control group. The proportion of mixed-calcified plaques in the study group was higher than in the other. Type III plaques have a 76.2% sensitivity and negative predictive value was 64.5% for acute coronary events; type IV plaques have a sensitivity of 52.6% and positive predictive value of 63% for chronic coronary events.


CONCLUSIONS
CCTA may be used as a non-invasive modality for evaluating and predicting vulnerable coronary atherosclerosis plaques in patients with type 2 diabetes.
Department of Radiology, Beijing Friendship Hospital, Capital Medical University, 95 Yongan Road, Xicheng District, Beijing 100050, China.
Daliang
0000-0002-3496-2174
D
Liu
Department of Radiology, Liaocheng People's Hospital, 67 West-Dongchang Road, Liaocheng, Shandong 252000, China.
Huijuan
H
Jia
Department of Radiology, Liaocheng People's Hospital, 67 West-Dongchang Road, Liaocheng, Shandong 252000, China.
Yucun
Y
Fu
Department of Radiology, Beijing Friendship Hospital, Capital Medical University, 95 Yongan Road, Xicheng District, Beijing 100050, China.
Wen
W
He
Department of Radiology, Beijing Friendship Hospital, Capital Medical University, 95 Yongan Road, Xicheng District, Beijing 100050, China.
Daqing
D
Ma
D054058:Acute Coronary Syndrome / Q000209:etiology; D000368:Aged; D016893:Carotid Stenosis / Q000209:etiology; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D003925:Diabetic Angiopathies / Q000000981:diagnostic imaging* / Q000503:physiopathology; D042241:Early Diagnosis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D061205:Vascular Calcification / Q000209:etiology