Bone loss in patients with the ileostomy and ileal pouch for inflammatory bowel disease.
Low bone mineral density (BMD) or low bone mass is common in patients with inflammatory bowel disease (IBD). Studies have shown that low BMD is also common in patients with ulcerative colitis (UC) even after colectomy and ileal pouch-anal anastomosis (IPAA). The reported frequency of osteopenia ranged from 26-55% and that of osteoporosis ranged from 13-32% in patients with IPAA. Increasing age, low body mass index, lack of calcium supplementation and high inflammatory activity with villous atrophy in the ileo-anal pouch are risk factors for low bone mass in pouch patients. Bone loss is also common in patients with IBD and ostomy. Current professional society guidelines do not specifically address the need for surveillance in patients with ileal pouches or ostomy. A growing body of evidence suggests that patients with ileal pouch or ostomy are at an increased risk of bone loss. Pending prospective studies, screening and surveillance using dual energy X-ray absorptiometry (DEXA) along with calcium/vitamin D supplementation may be beneficial in those patients.
Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio.
Supriya
S
Gupta
Bo
B
Shen
Bone loss; Crohn’s disease; inflammatory bowel disease; ulcerative colitis