Cerebral candidiasis in a 4-year-old boy after intestinal surgery.
Cerebral candidiasis is a devastating disease which contributes to a high mortality. Most of the cerebral candidiasis are never microbiologically or radiologically confirmed. In this case, a 4-year-old boy who developed cerebral candidiasis was successfully rescued and presented. The diagnosis of cerebral candidiasis was established based on both microbiologic and radiologic examinations. The pathogen was revealed to be Candida albicans by cerebrospinal fluid and central venous catheter cultures, and the cerebral involvement was recorded by series head magnetic resonance imaging (MRI) with an appearance of special encephalitis demonstrated. The imaging studies played a critical role throughout the diagnosis and treatment. Familiarity with the imaging findings in the appropriate clinical setting may result in a heightened level of awareness of this infection and, consequently, in earlier diagnosis and treatment.
Department of Pediatrics, Shengjing Hospital, China Medical University, Shenyang, China zhangshucheng76@126.com.
Shu-Cheng
SC
Zhang
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000188:drug therapy / Q000209:etiology*; D002437:Cefazolin / Q000627:therapeutic use; D002540:Cerebral Cortex / Q000473:pathology*; D002675:Child, Preschool; D004065:Digestive System Abnormalities; D006801:Humans; D045822:Intestinal Volvulus / Q000151:congenital / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D011183:Postoperative Complications / Q000503:physiopathology*
D000900:Anti-Bacterial Agents; D002437:Cefazolin
Candida albicans; amphotericin B; cerebral candidiasis; fluconazole; voriconazole