Potassium-rich diet and risk of stroke: updated meta-analysis.
Recently a few prospective population studies provided additional and heterogeneous information concerning the reported statistical associations between potassium (K) intake and stroke risk. Therefore, we updated our previous meta-analysis of K intake and risk of cerebrovascular events. Three studies were added to the previous analysis, and the results of the comparison between the event rate in the two extreme categories of K intake were used. Pooled analysis of 14 cohorts (overall 333,250 participants and 10,659 events) showed an inverse and significant association between K intake and risk of stroke (Relative Risk: 0.80; 95% CI: 0.72-0.90). Our results indicated a favorable effect of higher K intake on risk of stroke. These results confirm the appropriateness of worldwide recommendations for a population increased consumption of potassium-rich foods to prevent cardiovascular disease.
Department of Clinical Medicine and Surgery, ESH - Excellence Center for Hypertension, "Federico II" University of Naples Medical School, Naples, Italy. Electronic address: lanfranco.delia@unina.it.
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D'Elia
Department of Clinical Medicine and Surgery, ESH - Excellence Center for Hypertension, "Federico II" University of Naples Medical School, Naples, Italy.
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Iannotta
Department of Clinical Medicine and Surgery, ESH - Excellence Center for Hypertension, "Federico II" University of Naples Medical School, Naples, Italy.
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Sabino
Department of Clinical Medicine and Surgery, ESH - Excellence Center for Hypertension, "Federico II" University of Naples Medical School, Naples, Italy.
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Ippolito
D002561:Cerebrovascular Disorders / Q000453:epidemiology / Q000517:prevention & control; D015331:Cohort Studies; D019317:Evidence-Based Medicine; D005260:Female; D006293:Health Promotion; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D008297:Male; D010349:Patient Compliance; D011191:Potassium Deficiency / Q000178:diet therapy / Q000503:physiopathology; D017419:Potassium, Dietary / Q000009:adverse effects / Q000627:therapeutic use*; D011446:Prospective Studies; D064167:Recommended Dietary Allowances; D012306:Risk; D012727:Sex Characteristics; D020521:Stroke / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*
D017419:Potassium, Dietary
Diet; Meta-analysis; Potassium; Stroke