[Timing of clamping and factors associated with iron stores in full-term newborns].
OBJECTIVE
To analyze the impact of timing of clamping and obstetric, biological and socioeconomic factors on the iron stores of full-term newborns.


METHODS
Cross-sectional study between October 2011 and July 2012 in which hematological parameters were evaluated for newborns in Viçosa, MG, Southeastern Brazil. It involved collecting 7 mL of umbilical cord blood from 144 full-term not underweight newborns. The parameters investigated were complete blood count, serum iron, ferritin and C-reactive protein. The time of umbilical cord clamping was measured using a digital timer without interfering in the procedures of childbirth. The birth data were collected from Live Birth Certificates and other information was obtained from the mother through a questionnaire applied in the first month postpartum. Analysis of multiple linear regression was then used to estimate the influence of biological, obstetrics and socioeconomic factors on the ferritin levels at birth.


RESULTS
The median ferritin was 130.3 µg/L (n = 129, minimum = 16.4; maximum = 420.5 µg/L), the mean serum iron was 137.9 μg/dL (n = 144, SD = 39.29) and mean hemoglobin was 14.7 g/dL (n = 144, SD = 1.47). The median time of cord clamping was 36 seconds, ranging between 7 and 100. The bivariate analysis detected an association between ferritin levels and color of the child, timing clamping of 60 seconds, type of delivery, the presence of gestational diabetes and per capita family income. In multivariate analysis, the variables per capita income, number of antenatal visits and length at birth accounted for 22.0% of variation in ferritin levels.


CONCLUSIONS
Iron stores at birth were influenced by biological, obstetric and social characteristics. Tackling anemia should involve creating policies aimed at reducing social inequalities, improving the quality of antenatal care, as well as implementing a criterion of delayed clamping of the umbilical cord within the guidelines of labor.
Fabiana de Cássia Carvalho
Fde C
Oliveira
Karine Franklin
KF
Assis
Mariana Campos
MC
Martins
Mara Rúbia Maciel Cardoso do
MR
Prado
Andréia Queiroz
AQ
Ribeiro
Luciana Ferreira da Rocha
LF
Sant'Ana
Silvia Eloiza
SE
Priore
Sylvia do Carmo Castro
Sdo C
Franceschini
D000293:Adolescent; D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000517:prevention & control*; D001938:Brazil; D003250:Constriction; D003430:Cross-Sectional Studies; D005260:Female; D005293:Ferritins / Q000097:blood*; D005312:Fetal Blood / Q000737:chemistry*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D015999:Multivariate Analysis; D012959:Socioeconomic Factors; D013997:Time Factors; D014470:Umbilical Cord; D055815:Young Adult
D005293:Ferritins