Essential oil composition and antimicrobial activity of Angelica archangelica L. (Apiaceae) roots.
In this paper, the chemical composition and the antimicrobial activity of the essential oil of Angelica archangelica L. (Apiaceae) roots from central Italy were analyzed. The major constituents of the oil were α-pinene (21.3%), δ-3-carene (16.5%), limonene (16.4%) and α-phellandrene (8.7%). The oil shows a good antimicrobial activity against Clostridium difficile, Clostridium perfringens, Enterococcus faecalis, Eubacterium limosum, Peptostreptococcus anaerobius, and Candida albicans with minimum inhibitory concentration (MIC) values of 0.25, 0.25, 0.13, 0.25, 2.25, and 0.50% v/v, respectively. A weaker antimicrobial activity against bifidobacteria and lactobacilli-very useful in the intestinal microflora-has also been shown with MIC values >4.0% v/v.
1 Department of Biomolecular Science, University of Urbino "Carlo Bo ," Urbino, Italy .
Daniele
D
Fraternale
Guido
G
Flamini
Donata
D
Ricci
D029970:Angelica archangelica / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000032:analysis / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000032:analysis / Q000494:pharmacology*; D000935:Antifungal Agents / Q000032:analysis / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D000081008:Bicyclic Monoterpenes; D002176:Candida albicans / Q000187:drug effects*; D053138:Cyclohexenes / Q000032:analysis / Q000494:pharmacology; D000077222:Limonene; D008826:Microbial Sensitivity Tests; D039821:Monoterpenes / Q000032:analysis / Q000494:pharmacology; D009822:Oils, Volatile / Q000737:chemistry / Q000494:pharmacology*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry; D013729:Terpenes / Q000032:analysis / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D000081008:Bicyclic Monoterpenes; D053138:Cyclohexenes; D039821:Monoterpenes; D009822:Oils, Volatile; D010936:Plant Extracts; D013729:Terpenes; D000077222:Limonene; C030218:3-carene; C005451:alpha-pinene
Angelica archangelica; antimicrobial activity; bifidobacteria; essential oil; lactobacilli