Inefficacy of antipsychotics in treatment of delirium and agitation in two cases of bickerstaff brainstem encephalitis.
The authors report two unusual cases of Bickerstaff encephalitis that presented with encephalopathy and severe agitation. Management with neuroleptics typically used for management of delirium was not effective and worsened agitation. Valproic acid was effective in treatment of agitation and well tolerated.
Abdulkader
A
Alam
Neil V
NV
Puri
D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001933:Brain Stem / Q000473:pathology*; D003693:Delirium / Q000188:drug therapy*; D004569:Electroencephalography; D004660:Encephalitis / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011595:Psychomotor Agitation / Q000188:drug therapy*
D014150:Antipsychotic Agents