[Analysis of scatter plots and alarm information in 288 cases of newly diagnosed hematologic malignancies].
This study was aimed to explore the role of full-automatic blood analyzer Sysmex XE-2100 in early screening and diagnosing the hematologic malignancies. A total of 288 samples of the patients with hematologic malignancies was examined. Then, the scatter plots, alarm information and blood smears were analyzed. The results indicated that 76% of these samples showed abnormal scatter plots. CMML and AML-M3 patients had their own characteristic scatter plots, while others hadnt's. The coincident rate of CMML and AML-M3 determined by scatter plots with practical diseases was 100%; the coincident rate of ALL determined by scatter plots with practical disease was 67%. The coincident rate of alarm information of blast cells was 92.5%, the coincident rate of immature granulocytes was 77.1%, the coincident rate of nucleated red blood cells was 33.3%, the coincident rate of atypical lymphocytes was 31.3%. It is concluded that the abnormal scatter plots and alarm information are very important for finding the patients with hematologic malignancies and determining the disease type. The alarm information has high reliability for blast cells and immature granulocytes, but has only mirror value for nucleated red blood cells and atypical lymphocytes.
Department of Clinical Laboratorial Examination, Zhejiang Provincial Traditional Chinese Medicine Hospital, Hangzhou 310018, Zhejiang Province, China. E-mail: liangjueliu@263.com.
Liang-Jue
LJ
Liu
Department of Clinical Laboratorial Examination, Zhejiang Provincial Traditional Chinese Medicine Hospital, Hangzhou 310018, Zhejiang Province, China.
Feng
F
Luo
Department of Clinical Laboratorial Examination, Zhejiang Provincial Traditional Chinese Medicine Hospital, Hangzhou 310018, Zhejiang Province, China.
Ming-Hong
MH
Sun
Department of Clinical Laboratorial Examination, Zhejiang Provincial Traditional Chinese Medicine Hospital, Hangzhou 310018, Zhejiang Province, China.
Zhi-Qiang
ZQ
Zhong
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D019337:Hematologic Neoplasms / Q000097:blood*; D006403:Hematologic Tests / Q000295:instrumentation* / Q000379:methods*; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D055815:Young Adult