[Whipple's disease in a patient with infantile cerebral palsy and hepatitis B virus cirrhosis].
The paper describes a patient who has developed Whipple's disease in the presence of infantile cerebral palsy and hepatitis B virus cirrhosis. After 5-year treatment with co-trimoxazole (480 mg b.i.d.), the clinical manifestations subsided and PAS-positive macrophages were no longer detectable in the small intestinal mucosal biopsy specimens. Subsequent worsening of the patient's condition was associated with the progression of liver cirrhosis.
L M
LM
Krums
E A
EA
Sabelnikova
E V
EV
Golovanova
B Z
BZ
Chikunova
A I
AI
Parfenov
D000328:Adult; D001706:Biopsy; D002547:Cerebral Palsy / Q000150:complications / Q000503:physiopathology*; D018450:Disease Progression; D006509:Hepatitis B / Q000150:complications* / Q000473:pathology; D006801:Humans; D008103:Liver Cirrhosis / Q000821:virology*; D008264:Macrophages / Q000378:metabolism; D008297:Male; D016896:Treatment Outcome; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use; D008061:Whipple Disease / Q000188:drug therapy / Q000503:physiopathology*
D015662:Trimethoprim, Sulfamethoxazole Drug Combination