Defective auditory processing in a child with temporal epileptic focus.
A 9-year-old boy presented with intolerance to noise that was a trigger for violent temper tantrums that occasionally resembled complex partial seizures. The condition was also a cause for withdrawal from all activities and settings that could potentially be associated with noise. Both electroencephalography and magnetoencephalography clearly demonstrated a left temporal (T5) epileptic focus, although the child never had convulsive seizures. Genetic studies failed to reveal a GRIN2A mutation. We suggest that the hyperacusis in the reported child is another variation of the Landau-Kleffner spectrum.
Department of Pediatric Neurology and Epilepsy Center, Schneider Children's Medical Center of Israel, Petah Tiqva, Israel, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel avinoams@clalit.org.il.
Avinoam
A
Shuper
Gonda Brain Research Center, Bar Ilan University, Israel.
Mordechai
M
Medvedovsky
Department of Pediatric Neurology and Epilepsy Center, Schneider Children's Medical Center of Israel, Petah Tiqva, Israel, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Sara
S
Kivity
D001307:Auditory Perception / Q000502:physiology*; D001921:Brain / Q000503:physiopathology; D002648:Child; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000188:drug therapy / Q000235:genetics / Q000503:physiopathology*; D006801:Humans; D015225:Magnetoencephalography; D008297:Male
Landau-Kleffner; hyperacusis; temper tantrums; temporal epileptic focus