Neospora caninum versus Brucella spp. exposure among dairy cattle in Ethiopia: a case control study.
This case-control study aimed at assessing the relative association of Neospora caninum and Brucella species exposure with reproductive disorders. The study was carried out between October 2011 and June 2012 on 731 dairy cows sampled from 150 dairy farms in selected 17 conurbations of Ethiopia. Two hundred sixty-six of the cows were categorized as cases based on their history of abortion or stillbirth while the remaining 465 were controls. The presence of antibody to N. caninum was screened using indirect ELISA, while Brucella spp. exposure was assayed serially using Rose Bengal Plate Test and Complement Fixation Test. Exposure to N. caninum was more frequently observed among cases (23.8%) than controls (12.7%), while no significant difference (p > 0.05) was noted for Brucella exposure between the two groups. Moreover, the proportion of cows with disorders like retention of fetal membrane, endometritis and increased inter-calving period were significantly higher (p < 0.05) among Neospora seropositive cows. In conclusion, the finding discloses the strong association of N. caninum with reproductive disorders compared to Brucella spp. exposure. However, neither N. caninum nor Brucella spp. could explain the majority (73.2%) of the reported abortions and stillbirths in cattle. Hence, this observation underscores the need for more intensive investigation on the identification of causes of the aforementioned disorders in dairy cattle of Ethiopia.
Hawassa University School of Veterinary Medicine, P. O. box 005, Hawassa, Ethiopia, ka7588@yahoo.com.
Kassahun
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Asmare
D000034:Abortion, Veterinary / Q000209:etiology* / Q000382:microbiology / Q000469:parasitology; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D002002:Brucella / Q000276:immunology* / Q000302:isolation & purification; D002007:Brucellosis, Bovine / Q000150:complications* / Q000276:immunology / Q000473:pathology; D016022:Case-Control Studies; D002417:Cattle; D002418:Cattle Diseases / Q000209:etiology* / Q000382:microbiology / Q000469:parasitology; D003048:Coccidiosis / Q000150:complications / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005002:Ethiopia; D005260:Female; D018688:Neospora / Q000276:immunology* / Q000302:isolation & purification; D011247:Pregnancy
D000913:Antibodies, Protozoan