3-[2-(4-Fluoro-phen-yl)-2-oxoeth-yl]-5,5-di-phenyl-imidazolidine-2,4-dione.
The title compound, C23H17FN2O3, crystallizes with two independent mol-ecules in the asymmetric unit. The mol-ecules are connected by pairs of N-H⋯O hydrogen bonds and have slightly different conformations, as indicated by the dihedral angles between the central imidazolidine-2,4-dione ring and its three substituents. In one mol-ecule, these are 60.56 (1) and 82.66 (9)° to the phenyl rings and 84.35 (16)° to the 2-(4-fluoro-phen-yl)-2-oxoethyl side chain. In the other mol-ecule, the corresponding angles are 66.35 (10), 84.94 (9) and 86.31 (16)°. In the crystal, weak C-H⋯O inter-actions leading to a three-dimensional supramolecular architecture.
Department of Chemistry, Tulane University, New Orleans, LA 70118, USA.
Joel T
JT
Mague
Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia ; Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura, Mansoura 35516, Egypt.
Alaa A-M
AA
Abdel-Aziz
Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia ; Department of Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Cairo 11884, Egypt.
Adel S
AS
El-Azab