Two new cucurbitane triterpenoids from the seeds of Momordica charantia.
Two new cucurbitane triterpenoids 1 and 2 were isolated, together with six known compounds, from the seeds of Momordica charantia L. The structures of new compounds were determined to be 3-O-{[β-d-galactopyranosyl(1 → 6)]-O-β-d-galactopyranosyl}-23(R), 24(R), 25-trihydroxycucur-bit-5-ene (1), 3-O-[β-d-galactopyranosyl]-25-O-β-d-galactopyranosyl-7(R), 22(S), 23(R), 24(R), 25-pentahydroxycucurbit-5-ene (2), respectively. Their structures were elucidated by the combination of mass spectrometry, one- and two-dimensional NMR experiments and chemical reactions.
a State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing 100050 , China.
Lin
L
Ma
Ai-Hua
AH
Yu
Li-Li
LL
Sun
Wan
W
Gao
Meng-Meng
MM
Zhang
Ya-Lun
YL
Su
Hua
H
Liu
Teng-Fei
TF
Ji
Di-Zao
DZ
Li
D005638:Fruit / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D029777:Momordica charantia / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D012639:Seeds / Q000737:chemistry; D013237:Stereoisomerism; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
C000589405:3-O-((beta-D-galactopyranosyl(1-6))-O-beta-D-galactopyranosyl)-23(R),24(R),25-trihydroxycucur-bit-5-ene; C000589406:3-O-(beta-D-galactopyranosyl)-25-O-beta-D-galactopyranosyl-7(R),22(S),23(R),24(R),25-pentahydroxycucurbit-5-ene; D006027:Glycosides; D014315:Triterpenes; C514277:cucurbitane
Cucurbitaceae; Momordica charantia; cucurbitane triterpenoids; seeds