Acyclic sulfides, garlicnins L-1-L-4, E, and F, from Allium sativum.
Six novel acyclic sulfides, named garlicnins L-1-L-4 (1-4), E (5), and F (6), were isolated from the acetone extracts, with the ability to suppress M2 macrophage activation, of the bulbs of garlic (Allium sativum L.), and their chemical structures were characterized.
Faculty of Pharmaceutical Sciences, Sojo University.
Toshihiro
T
Nohara
Yukio
Y
Fujiwara
Tsuyoshi
T
Ikeda
Koki
K
Yamaguchi
Hideyuki
H
Manabe
Kotaro
K
Murakami
Masateru
M
Ono
Daisuke
D
Nakano
Junei
J
Kinjo
D005737:Garlic / Q000737:chemistry*; D006801:Humans; D008264:Macrophages / Q000187:drug effects*; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D013440:Sulfides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D013876:Thiophenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*
D013440:Sulfides; D013876:Thiophenes