Plasmacytoid dendritic cell depletion in DOCK8 deficiency: rescue of severe herpetic infections with IFN-α 2b therapy.
Division of Pediatric Immunology and Allergy, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey; Division of Immunology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Mass. Electronic address: sevgi.keles@childrens.harvard.edu.
Sevgi
S
Keles
Division of Immunology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
Haifa H
HH
Jabara
Division of Pediatric Immunology and Allergy, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.
Ismail
I
Reisli
Division of Immunology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
Douglas R
DR
McDonald
Division of Pediatric Allergy and Immunology, Marmara University Faculty of Medicine, Istanbul, Turkey.
Isil
I
Barlan
Division of Pediatric Infectious Diseases, American University of Beirut, Beirut, Lebanon.
Rima
R
Hanna-Wakim
Division of Pediatric Infectious Diseases, American University of Beirut, Beirut, Lebanon.
Ghassan
G
Dbaibo
University Montpellier 2 and Institute of Human Genetics, CNRS UPR 1142, Montpellier, France.
Gerard
G
Lefranc
Department of Pediatrics, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait.
Waleed
W
Al-Herz
Division of Immunology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
Raif S
RS
Geha
Division of Immunology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Mass. Electronic address: talal.chatila@childrens.harvard.edu.
Talal A
TA
Chatila
D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003713:Dendritic Cells / Q000276:immunology* / Q000378:metabolism; D005260:Female; D020662:Guanine Nucleotide Exchange Factors / Q000172:deficiency*; D006566:Herpesviridae Infections / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D006720:Homozygote; D006801:Humans; D016130:Immunophenotyping; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use; D009154:Mutation; D011994:Recombinant Proteins / Q000627:therapeutic use; D016511:Severe Combined Immunodeficiency / Q000235:genetics / Q000276:immunology; D016896:Treatment Outcome
D000998:Antiviral Agents; C516591:DOCK8 protein, human; D020662:Guanine Nucleotide Exchange Factors; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins