Molecular modelling, spectroscopic characterization and biological studies of tetraazamacrocyclic metal complexes.
Macrocyclic complexes of the type [MLX]X2; where L is (C30H28N4), a macrocyclic ligand, M=Cr(III) and Fe(III) and X=Cl-, CH3COO- or NO3-, have been synthesized by template condensation reaction of 1,8-diaminonaphthalene and acetylacetone in the presence of trivalent metal salts in a methanolic medium. The complexes have been formulated as [MLX]X2 due to 1:2 electrolytic nature of these complexes. The complexes have been characterized with the help of elemental analyses, molar conductance measurements, magnetic susceptibility measurements, electronic, infrared, far infrared, Mass spectral studies and molecular modelling. Molecular weight of these complexes indicates their monomeric nature. On the basis of all these studies, a five coordinated square pyramidal geometry has been proposed for all these complexes. These metal complexes have also been screened for their in vitro antimicrobial activities.
Chemistry Department, National Institute of Technology, Kurukshetra 136 119, India. Electronic address: rathiparveen28@gmail.com.
Parveen
P
Rathi
Chemistry Department, National Institute of Technology, Kurukshetra 136 119, India.
Kavita
K
Sharma
Chemistry Department, National Institute of Technology, Kurukshetra 136 119, India.
Dharam Pal
DP
Singh
D000935:Antifungal Agents / Q000737:chemistry; D001412:Bacillus subtilis; D002176:Candida albicans; D002614:Chelating Agents / Q000737:chemistry; D004926:Escherichia coli; D008024:Ligands; D047028:Macrocyclic Compounds / Q000737:chemistry*; D008280:Magnetics; D008670:Metals / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D008958:Models, Molecular; D008968:Molecular Conformation; D009281:Naphthalenes / Q000737:chemistry; D010422:Pentanones / Q000737:chemistry; D011550:Pseudomonas aeruginosa; D012441:Saccharomyces cerevisiae; D012492:Salts / Q000737:chemistry; D012995:Solubility; D013053:Spectrophotometry; D013055:Spectrophotometry, Infrared
D000935:Antifungal Agents; D002614:Chelating Agents; D008024:Ligands; D047028:Macrocyclic Compounds; D008670:Metals; D009281:Naphthalenes; D010422:Pentanones; D012492:Salts; C031721:naphthalene; C008790:acetylacetone
Antimicrobial; Infrared; Macrocyclic; Mass spectra; Molecular modelling; Template