Sertoli-leydig cell tumor of ovary- a diagnostic dilemma.
Sertoli Leydig Cell Tumours (SLCTs) are rare, unilateral, sex cord stromal tumours of ovary, which constitute less than 1% of all the ovarian neoplasms. These tumours can be functionally diverse and they may have heterologous elements. We aim to report a case of a 25-year- old woman who presented with suprapubic pain of 5 days duration, a unilateral adnexal mass, hypertestosteronism without virilization. Intraoperative frozen section of the unilateral salpingo-oophorectomy specimen was suggestive of granulosa cell tumour. Histopathological examination, supplemented with alpha-inhibin immunohistochemistry, was diagnostic of Meyer's type II SLCT. Clinical presentation, pathology and the diagnostic pitfalls in the present case have been presented with a brief review of literature.
Tutor, Department of Pathology, Dr. B.R. Ambedkar Medical College and Hospital , Bangalore, India .Ex-Senior Resident,Department of Pathology, Pondicherry Institute of Medical Sciences , Ganapathychettykulam, Kalapet, Puducherry, India .
Rohini Dhanya
RD
C S
Assistant Professor, Department of Pathology, Pondicherry Institute of Medical Sciences , Ganapathychettykulam, Kalapet, Puducherry, India .
Somanath
S
Padhi
Professor and HOD, Department of Pathology, Pondicherry Institute of Medical Sciences , Ganapathychettykulam, Kalapet, Puducherry, India .
Renu G'boy
RG
Varghese
Alfa-Inhibin; Frozen section; Ovary; Sertoli-Leydig cell tumour