[Rosai-Dorfman disease presented with involvement of the adrenal gland. A clinical case reported].
BACKGROUND
Adrenal gland involvement is a very rare extranodal presentation of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease). Its pathogenesis still remains unknown with many theories about its probable cause. Symptoms and signs of adrenal involvement presentation are uncertain. Although, it is a disease with a good prognosis and a favorable clinical course in most cases, the low index of suspicion and difficulty in radiological differential diagnosis lead to radical treatment.


METHODS
We present a case of Rosai-Dorfman disease with right adrenal plus left infrahiliar nodal involvement. It was treated with adrenalectomy and node exeresis. The infrahilial involvement evolution was appropriate.


CONCLUSIONS
Rosai-Dorfman disease is a rare disease and the extra-nodal presentation is even more rare. The incidence and evolution of this disease in the adrenal gland is unknown. The presence of this pathology should be considered if the patient shows adrenal gland affected and lymph node growth, in order to consider the individualized treatment, which may vary (treatment with corticosteroids, chemotherapy and/or radiotherapy).
Servicio de Urología, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Distrito Federal, México. mfc_victor@hotmail.com.
Víctor Manuel
VM
Flores-Carrillo
Félix
F
Santaella-Torres
Luis Carlos
LC
Sánchez-Martínez
Miguel Humberto
MH
Gómez-Lara
Moisés
M
Arellano-Poblete
Eduardo
E
López Segura-Rueda
Jorge
J
Villarroel-Noboa
D000307:Adrenal Gland Diseases / Q000209:etiology*; D005260:Female; D015618:Histiocytosis, Sinus / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008875:Middle Aged
Adrenal gland neoplasms; Sinus histiocytosis