An environmentally benign protocol for aqueous synthesis of tetrahydrobenzo[b]pyrans catalyzed by cost-effective ionic liquid.
A mild, efficient, and environmentally benign protocol for the synthesis of tetrahydrobenzo[b]pyran derivatives in the presence of readily accessible, biodegradable, and choline hydroxide based ionic liquid as catalyst has been established. The key features of the reported methodology include good to excellent yields of desired products, simple work-up procedure and good recyclability of catalysts, which may be a practical alternative to the existing conventional processes for the preparation of 4-H pyrans to cater to the requirements of academia as well as industry.
Institute of Applied Chemistry, Taizhou University, Taizhou 318000, China. hhn12192000@126.com.
Huanan
H
Hu
Institute of Applied Chemistry, Taizhou University, Taizhou 318000, China. lhqiu123@163.com.
Fangli
F
Qiu
Institute of Applied Chemistry, Taizhou University, Taizhou 318000, China. agying@tzc.edu.cn.
Anguo
A
Ying
Institute of Applied Chemistry, Taizhou University, Taizhou 318000, China. yjg@tzc.edu.cn.
Jianguo
J
Yang
School of Pharmaceutical and Chemical Engineering, Taizhou University, Taizhou 318000, China. mhp@tzc.edu.cn.
Haiping
H
Meng
D001673:Biodegradation, Environmental; D002384:Catalysis; D002794:Choline / Q000737:chemistry; D052578:Ionic Liquids / Q000737:chemistry*; D011714:Pyrans / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism
D052578:Ionic Liquids; D011714:Pyrans; D002794:Choline