Scrotal extratesticular schwannoma: a case report and review of the literature.
BACKGROUND
Schwannomas are tumours arising from Schwann cells, which sheath the peripheral nerves. Here, we report a rare case of left intrascrotal, extratesticular schwannoma. Although rare, scrotal localisation of schwannomas has been reported in male children, adult men, and elderly men. They are usually asymptomatic and are characterised by slow growth. Patients generally present with an intrascrotal mass that is not associated with pain or other clinical signs, and such cases are self-reported by most patients. Imaging modalities (such as ultrasonography, computed tomography, and magnetic resonance imaging) can be used to determine tumour size, exact localisation, and extension. However, the imaging findings of schwannoma are non-specific. Therefore, only complete surgical excision can result in diagnosis, based on histological and immunohistochemical analyses. If the tumour is not entirely removed, recurrences may develop, and, although malignant change is rare, this may occur, especially in patients with a long history of an untreated lesion. Thus, follow up examinations with clinical and imaging studies are recommended for scrotal schwannomas.


METHODS
A 52-year-old man presented with a 3-year history of asymptomatic scrotal swelling. Physical examination revealed a palpable, painless, soft mass in the left hemiscrotum. After surgical removal of the mass, its histological features indicated schwannoma.


CONCLUSIONS
Schwannoma should be considered in cases of masses that are intrascrotal but extratesticular. Ultrasonography provides the best method of confirming the paratesticular localisation of the tumour, before surgical removal allows histopathological investigation and definitive diagnosis. Surgery is the standard therapeutic approach. To prevent recurrence, particular care should be taken to ensure complete excision. This case report includes a review of the literature on scrotal schwannomas.
Giovanni
G
Palleschi
Antonio
A
Carbone
Jessica
J
Cacciotti
Giorgia
G
Manfredonia
Natale
N
Porta
Andrea
A
Fuschi
Cosimo
C
de Nunzio
Vincenzo
V
Petrozza
Sapienza University of Rome, Department of Medical and Surgical Biotechnologies, Unit of Urology, ICOT, Via Franco Faggiana 1668, 04100 Latina, Italy. antopast@hotmail.com.
Antonio Luigi
AL
Pastore
D005834:Genital Neoplasms, Male / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009442:Neurilemmoma / Q000473:pathology* / Q000601:surgery*; D012611:Scrotum / Q000473:pathology* / Q000601:surgery*; D013736:Testicular Neoplasms / Q000473:pathology / Q000601:surgery