Cardiac involvement secondary to mediastinal lymphoma in a cat: regression with chemotherapy.
Mediastinal lymphoma with neoplastic invasion into the heart was diagnosed in a 9-year-old castrated male domestic short hair cat. The neoplastic infiltrate was seen throughout the atria and atrial septum, surrounded the aortic root, and resulted in narrowing of the right ventricular outflow tract. Chemotherapy resulted in resolution of the echocardiographic abnormalities and the cat's clinical signs until the patient was euthanized 58 days later following development of neurologic signs. Mediastinal lymphoma with myocardial invasion and response to chemotherapy has not been documented previously in the veterinary literature.
Oradell Animal Hospital, 580 Winters Ave, Paramus, NJ 07652, USA. Electronic address: jshih@oradell.com.
Julia L
JL
Shih
Oradell Animal Hospital, 580 Winters Ave, Paramus, NJ 07652, USA.
Stephen
S
Brenn
Oradell Animal Hospital, 580 Winters Ave, Paramus, NJ 07652, USA.
Donald P
DP
Schrope
D000818:Animals; D000927:Anticonvulsants / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001215:Asparaginase / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D002371:Cat Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D002415:Cats; D004359:Drug Therapy, Combination; D004452:Echocardiography / Q000662:veterinary; D037901:Euthanasia, Animal; D017809:Fatal Outcome; D006338:Heart Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary*; D000077287:Levetiracetam; D008130:Lomustine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D008223:Lymphoma / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D008297:Male; D008479:Mediastinal Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D009361:Neoplasm Invasiveness / Q000000981:diagnostic imaging / Q000473:pathology; D010889:Piracetam / Q000031:analogs & derivatives / Q000627:therapeutic use; D012640:Seizures / Q000139:chemically induced / Q000188:drug therapy / Q000662:veterinary
D000927:Anticonvulsants; D000970:Antineoplastic Agents; D000077287:Levetiracetam; D008130:Lomustine; D001215:Asparaginase; D010889:Piracetam
Cancer; Echocardiography; Feline; Pericardial effusion