Ahmed Glaucoma Valve Implantation for Uveitic Glaucoma Secondary to Behçet Disease.
OBJECTIVE
To evaluate outcomes of patients with uveitic glaucoma secondary to Behçet disease (BD) who underwent Ahmed glaucoma valve (AGV) implantation.


METHODS
A retrospective chart review of 14 eyes of 10 patients with uveitic glaucoma associated with BD who underwent AGV implantation at a tertiary referral center. Treatment success was defined as intraocular pressure (IOP) between 6 and 21 mm Hg with or without antiglaucoma medication, without further additional glaucoma surgery or loss of light perception. The main outcome measures were IOP, best-corrected visual acuity measured with Snellen charts, and number of glaucoma medications.


RESULTS
Mean duration of postoperative follow-up was 18.2±6.6 months (range, 6 to 31 mo). Of the 14 eyes, 10 (71.4%) were pseudophakic and 5 (35.7%) had primary AGV implantation without a history of previous glaucoma surgery. At the most recent follow-up visit, 13 of the 14 eyes had an IOP between 6 and 21 mm Hg. Mean IOP was significantly reduced during follow-up, as compared with preoperative values (P≤0.005). The cumulative probability of surgical success rate was 90.9% at 18 months based on Kaplan-Meier survival analysis. The mean number of antiglaucoma medications required to achieve the desired IOP decreased from 3.4±0.5 preoperatively to 1.0±1.1 postoperatively (P≤0.05). Visual acuity loss of >2 lines occurred in 4 eyes (28.5%) due to optic atrophy associated with retinal vasculitis. Temporary hypotony developed during follow-up in 4 eyes (28.5%) at first postoperative week.


CONCLUSIONS
For the management of uveitic glaucoma associated with BD, AGV implantation is a successful method for glaucoma control but requires additional surgical interventions for high early hypotony rates.
*Beyoglu Eye Research and Training Hospital †Yeditepe University Medical School, Eye Clinic, Istanbul ‡Ankara Training and Research Hospital, Eye Clinic, Ankara, Turkey.
Banu
B
Satana
Ilgaz S
IS
Yalvac
Gulten
G
Sungur
Umit
U
Eksioglu
Berna
B
Basarir
Cigdem
C
Altan
Sunay
S
Duman
D000293:Adolescent; D000328:Adult; D001528:Behcet Syndrome / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005901:Glaucoma / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D020327:Glaucoma Drainage Implants; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D011183:Postoperative Complications / Q000601:surgery; D011184:Postoperative Period; D019919:Prosthesis Implantation; D012189:Retrospective Studies; D014065:Tonometry, Ocular; D016896:Treatment Outcome; D014606:Uveitis, Anterior / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult