Copper-promoted reductive coupling of aryl iodides with 1,1,1-trifluoro-2-iodoethane.
An efficient Cu-promoted reductive coupling of aryl iodides with 1,1,1-trifluoro-2-iodoethane has been developed. This reaction could occur in good yields under milder conditions as compared with previous studies. The reaction tolerated nitro, formyl, ester, ether, carbonyl, sulfonyl, and even azo groups.
School of Medical Engineering, School of Chemical Engineering, ‡Key Laboratory of Advanced Functional Materials and Devices, Hefei University of Technology , Anhui Province, Hefei 230009, P. R. China.
Song
S
Xu
Huan-Huan
HH
Chen
Jian-Jun
JJ
Dai
Hua-Jian
HJ
Xu
D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006846:Hydrocarbons, Halogenated / Q000138:chemical synthesis* / Q000737:chemistry*; D007454:Iodides / Q000737:chemistry*; D015394:Molecular Structure
D006846:Hydrocarbons, Halogenated; D007454:Iodides; D003300:Copper; C000591752:1,1,1-trifluoro-2-iodoethane