[Profile of effective donors from organ and tissue procurement services].
OBJECTIVE
To characterize the profile of effective organ and tissue donors and to understand which organs and tissues were donated for transplantation.


METHODS
This was a quantitative, descriptive, exploratory, retrospective study that analyzed clinical data from 305 donors between January 2006 to December 2010. The data were then analyzed using descriptive analyses, generating frequency tables, measures of position (mean, minimum and maximum) and measures of dispersion (standard deviation) for data that was social and clinical in nature.


RESULTS
There was an overall predominance of white (72%) and male (55%) individuals between the ages of 41 and 60 years (44%). The primary cause of brain death was cerebrovascular accident (55%). In the patient history, 31% of the patients were classified as overweight, 27% as hypertensive and only 4.3% as having diabetes mellitus. Vasoactive drugs were used in 92.7% of the donors, and the main drug of choice was noradrenaline (81.6%). Hyperglycemia and hypernatremia were diagnosed in 78% and 71% of the donors, respectively.


CONCLUSIONS
Significant hemodynamic changes were found, and the results indicate that the use of vasoactive drugs was the main strategy used to control these changes. Furthermore, most donors presented with hyperglycemia and hypernatremia, which were frequently reported in association with brain death. The persistent nature of these findings suggests that the organ donors were inadequately maintained.
Serviço de Procura de Órgãos e Tecidos, Hospital de Clínicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.
Simey de Lima Lopes
Sde L
Rodrigues
Instituto do Fígado, Real e Benemérita Associação Portuguesa de Beneficência, São Paulo, SP, Brasil.
Jose Ben-Hur de Escobar
JB
Ferraz Neto
Serviço de Procura de Órgãos e Tecidos, Hospital de Clínicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.
Luiz Antonio da Costa
LA
Sardinha
Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.
Sebastião
S
Araujo
Serviço de Procura de Órgãos e Tecidos, Hospital de Clínicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.
Helder Jose Lessa
HJ
Zambelli
Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.
Ilka de Fátima Santana Ferreira
Ide F
Boin
Serviço de Procura de Órgãos e Tecidos, Hospital de Clínicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.
Maria Valeria de Omena
MV
Athayde
Serviço de Procura de Órgãos e Tecidos, Hospital de Clínicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.
Eliete Bombarda Bachega
EB
Montone
Serviço de Procura de Órgãos e Tecidos, Hospital de Clínicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.
Marcia Raquel
MR
Panunto
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001926:Brain Death; D002423:Cause of Death; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000453:epidemiology*; D006955:Hypernatremia / Q000453:epidemiology*; D007223:Infant; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014019:Tissue Donors / Q000706:statistics & numerical data*; D009927:Tissue and Organ Procurement / Q000706:statistics & numerical data; D055815:Young Adult