Incidence of red blood cell transfusion in mechanically ventilated surgical patients at Siriraj Hospital.
BACKGROUND
Anemia is commonly encountering surgical critically ill patients. The incidence of red blood cell (RBC) transfusion and transfusion trigger in this population has not been previously reported in a large tertiary care center in Thailand


OBJECTIVE
To describe the incidence of RBC transfusion and transfusion trigger and to determine the factors and outcomes associated with RBC transfusion.


METHODS
Data of 288 adult surgical patients requiring mechanical ventilation for > 24 hours was retrospectively reviewed Patient characteristic, outcomes, and transfusion data were collected.


RESULTS
The incidence ofRBC transfusion was 83.0% (95% confidence interval (CI) 78.0-87.0%). The mean hemoglobin level before RBC transfusion was 8.7 +/- 1.2 g/dL. Patients who received RBC transfusion had significantly higher morbidity and mortality when compared with those who did not. Independent factors associated with RBC transfusion were low body weight, high Sequential Organ Failure Assessment (SOFA) score, and low hemoglobin level on admission (adjusted odds ratio 0.97, 1.19, and 0.60. respectively).


CONCLUSIONS
In critically ill adult surgical patients, the incidence of RBC transfusion and transfusion trigger remained within high threshold Large randomized controlled studies are warranted to confirm potential benefit of RBC transfusion in surgical critically ill patients.
Annop
A
Piriyapatsom
Onuma
O
Chaiwat
Jedsadayoot
J
Sak-Aroonchai
Worawan
W
Suwannasri
Sawita
S
Kanavitoon
D000368:Aged; D017707:Erythrocyte Transfusion / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012121:Respiration, Artificial; D012307:Risk Factors; D013514:Surgical Procedures, Operative; D013785:Thailand / Q000453:epidemiology