The path to personalised medicine in COPD.
Our understanding of chronic obstructive pulmonary disease (COPD) has changed dramatically over the past two decades. We have moved from an airflow limitation-centric view to the realisation that COPD is a complex and heterogeneous disease, which leads inevitably to the need for personalising the assessment and treatment of patients with COPD. This review provides a brief perspective of the extraordinary transition that the COPD field has experienced in the last two decades, and speculates on how it should/can move forward in the near future in order to really achieve the goal of personalising COPD medicine in the clinic.
Alvar
A
Agusti
D005541:Forced Expiratory Volume; D006801:Humans; D007249:Inflammation / Q000150:complications; D008168:Lung / Q000000981:diagnostic imaging / Q000382:microbiology; D010641:Phenotype; D057285:Precision Medicine; D029424:Pulmonary Disease, Chronic Obstructive / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000517:prevention & control / Q000628:therapy*; D011859:Radiography; D012720:Severity of Illness Index
COPD Pharmacology; COPD ÀÜ Mechanisms