Incidence and paris classification of pediatric inflammatory bowel disease.
New epidemiological data suggest that the incidence of inflammatory bowel disease (IBD) is increasing. As a result the burden of disease accounts for more strains to the health care system. The clinical variability queries whether disease characteristics are related to clinical outcome. Our aim was to delineate the latest results of incidence trends in pediatric IBD and to compare the first experiences with Paris Classification. Incidence of pediatric IBD has been increasing in Western Europe and in Eastern Europe. To better characterize IBD, Paris Classification was introduced and validated recently. Ileocolonic involvement is the most characteristic disease location in Crohn's disease (CD) based on applying Paris Classification. The rate of perianal disease and complicated behaviour in CD was similar. It is of interest that CD patients with colonic involvement were less likely to have stricturing disease compared with patients with ileal involvement. In addition, pancolitis dominated in ulcerative colitis (UC). However, most countries lack prospective, nationwide epidemiological studies to estimate incidence trends. This review emphasizes the importance of nationwide registries that enroll all pediatric IBD cases serving reliable data for "everyday practice." These first reports have shown that Paris Classification is a useful tool to determine the pediatric IBD phenotype.
1st Department of Pediatrics, Semmelweis University, 53 Bókay Street, Budapest 1083, Hungary.
Katalin
K
Eszter Müller
1st Department of Medicine, Semmelweis University, Korányi S. Street 26A, Budapest 1083, Hungary.
Peter
P
Laszlo Lakatos
2nd Department of Medicine, University of Debrecen, Nagyerdei Körút 98, Debrecen 4032, Hungary.
Maria
M
Papp
1st Department of Pediatrics, Semmelweis University, 53 Bókay Street, Budapest 1083, Hungary.
Gabor
G
Veres