Visualisation of contrast-enhanced intraoperative optical coherence tomography with indocyanine green.
Optical coherence tomography (OCT)-based visualisation of ophthalmic anatomy has transformed the clinical practice of ophthalmology. The translation of OCT into the surgical theatre is currently being actively researched and may provide a paradigm shift in surgical practice. Enhanced visualisation of tissues and tissue planes may provide further iterative improvement in surgeon feedback. Contrast-enhanced intraoperative OCT (iOCT) has been previously described with triamcinolone. In this report, we describe the OCT features and contrast enhancement noted with indocyanine green using iOCT in human subjects as well as an ex vivo analysis in porcine eyes.
Cole Eye Institute, Ophthalmic Imaging Center, Vitreoretinal Service, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Justis P
JP
Ehlers
Cole Eye Institute, Ophthalmic Imaging Center, Vitreoretinal Service, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Stephen
S
McNutt
Case Western Reserve School of Medicine, Cleveland, Ohio, USA.
Suhail
S
Dar
Cole Eye Institute, Ophthalmic Imaging Center, Vitreoretinal Service, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Yuankai K
YK
Tao
Cole Eye Institute, Ophthalmic Imaging Center, Vitreoretinal Service, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Sunil K
SK
Srivastava
D000818:Animals; D001485:Basement Membrane / Q000473:pathology*; D004396:Coloring Agents; D003287:Contrast Media; D019773:Epiretinal Membrane / Q000175:diagnosis*; D006801:Humans; D007208:Indocyanine Green; D007432:Intraoperative Period; D011239:Prednisolone / Q000031:analogs & derivatives; D012189:Retrospective Studies; D013552:Swine; D041623:Tomography, Optical Coherence / Q000379:methods*; D014222:Triamcinolone Acetonide
D004396:Coloring Agents; D003287:Contrast Media; C009935:prednisolone acetate; D011239:Prednisolone; D014222:Triamcinolone Acetonide; D007208:Indocyanine Green
Imaging; Treatment Surgery