title: Development of drug delivery systems based on layered hydroxides for nanomedicine.
abstract: Layered hydroxides (LHs) have recently fascinated researchers due to their wide application in various fields. These inorganic nanoparticles, with excellent features as nanocarriers in drug delivery systems, have the potential to play an important role in healthcare. Owing to their outstanding ion-exchange capacity, many organic pharmaceutical drugs have been intercalated into the interlayer galleries of LHs and, consequently, novel nanodrugs or smart drugs may revolutionize in the treatment of diseases. Layered hydroxides, as green nanoreservoirs with sustained drug release and cell targeting properties hold great promise of improving health and prolonging life.
authors.affiliation: Materials Synthesis and Characterization Laboratory, Institute of Advanced Technology (ITMA), Universiti Putra Malaysia, UPM, Serdang 43400, Malaysia. farahB2424@yahoo.com.
authors.forename: Farahnaz
authors.initials: F
authors.lastname: Barahuie
authors.affiliation: Materials Synthesis and Characterization Laboratory, Institute of Advanced Technology (ITMA), Universiti Putra Malaysia, UPM, Serdang 43400, Malaysia. mzobir@upm.edu.my.
authors.forename: Mohd Zobir
authors.initials: MZ
authors.lastname: Hussein
authors.affiliation: Laboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, UPM, Serdang 43400, Malaysia. sharida@medic.upm.edu.my.
authors.forename: Sharida
authors.initials: S
authors.lastname: Fakurazi
authors.affiliation: Materials Synthesis and Characterization Laboratory, Institute of Advanced Technology (ITMA), Universiti Putra Malaysia, UPM, Serdang 43400, Malaysia. zulkar@putra.upm.edu.my.
authors.forename: Zulkarnain
authors.initials: Z
authors.lastname: Zainal
mesh_terms: D000818:Animals; D060326:Chemistry Techniques, Synthetic / Q000379:methods; D003692:Delayed-Action Preparations / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism / Q000633:toxicity; D016503:Drug Delivery Systems / Q000379:methods; D006801:Humans; D006878:Hydroxides / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism / Q000633:toxicity; D008958:Models, Molecular; D050997:Nanomedicine; D053758:Nanoparticles / Q000737:chemistry* / Q000378:metabolism / Q000633:toxicity; D004364:Pharmaceutical Preparations / Q000008:administration & dosage*
chemical_list: D003692:Delayed-Action Preparations; D006878:Hydroxides; D004364:Pharmaceutical Preparations