title: Surgical management of periprosthetic joint infections: two-stage exchange.
abstract: The presence of a periprosthetic joint infection (PJI) following knee arthroplasty is devastating to the patient, with significant loss of function and independence, with risk of systemic compromise with sepsis and organ failure, and loss of life. This article reviews the management of knee PJIs, with particular emphasis on the two-stage exchange arthroplasty.
authors.affiliation: Department of Trauma and Orthopaedic Surgery, University College Hospital London, London, United Kingdom.
authors.forename: David A
authors.initials: DA
authors.lastname: George
authors.affiliation: Department of Trauma and Orthopaedic Surgery, University College Hospital London, London, United Kingdom.
authors.forename: Fares S
authors.initials: FS
authors.lastname: Haddad
mesh_terms: D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D003646:Debridement; D020878:Device Removal; D006801:Humans; D007719:Knee Joint / Q000382:microbiology / Q000601:surgery; D007720:Knee Prosthesis; D016459:Prosthesis-Related Infections / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology / Q000601:surgery*; D012086:Reoperation; D007507:Therapeutic Irrigation