title: Comprehensive exploration of autoantibody in Behçet's disease: a novel autoantibody to claudin-1, an essential protein for tight junctions, is identified.
authors.affiliation: Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine, Suita, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Atsuyoshi
authors.initials: A
authors.lastname: Morishima
authors.affiliation: Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine, Suita, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: thirano@imed3.med.osaka-u.ac.jp.
authors.forename: Toru
authors.initials: T
authors.lastname: Hirano
authors.affiliation: Department of Experimental Immunology, World Premier International Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan.
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Nishikawa
authors.affiliation: Department of Ophtalmology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
authors.forename: Kei
authors.initials: K
authors.lastname: Nakai
authors.affiliation: Department of Experimental Immunology, World Premier International Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan.
authors.forename: Shimon
authors.initials: S
authors.lastname: Sakaguchi
authors.affiliation: Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine, Suita, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan; Core Research for Evolutionary Science and Technology (CREST), Osaka University, Suita, Osaka, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kumanogoh
mesh_terms: D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000097:blood / Q000276:immunology; D001323:Autoantibodies / Q000097:blood / Q000276:immunology*; D001528:Behcet Syndrome / Q000097:blood / Q000276:immunology*; D015415:Biomarkers / Q000097:blood; D062445:Claudin-1 / Q000097:blood / Q000276:immunology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D040081:Protein Array Analysis; D019108:Tight Junctions / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D015415:Biomarkers; D062445:Claudin-1
keywords: Autoantibody; Behçet's disease; Claudin-1; Clinical marker; Protein microarray; Tight junctions