title: Graphene-based nanocomposite as an effective, multifunctional, and recyclable antibacterial agent.
abstract: The development of new antibacterial agents that are highly effective are of great interest. Herein, we present a recyclable and synergistic nanocomposite by growing both iron oxide nanoparticles (IONPs) and silver nanoparticles (AgNPs) on the surface of graphene oxide (GO), obtaining GO-IONP-Ag nanocomposite as a novel multifunctional antibacterial material. Compared with AgNPs, which have been widely used as antibacterial agents, our GO-IONP-Ag shows much higher antibacterial efficiency toward both Gram-negative bacteria Escherichia coli (E. coli) and Gram-positive bacteria Staphylococcus aureus (S. aureus). Taking the advantage of its strong near-infrared (NIR) absorbance, photothermal treatment is also conducted with GO-IONP-Ag, achieving a remarkable synergistic antibacterial effect to inhibit S. aureus at a rather low concentration of this agent. Moreover, with magnetic IONPs existing in the composite, we can easily recycle GO-IONP-Ag by magnetic separation, allowing its repeated use. Given the above advantages as well as its easy preparation and cheap cost, GO-IONP-Ag developed in this work may find potential applications as a useful antibacterial agent in the areas of healthcare and environmental engineering.
authors.affiliation: Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University , Suzhou, Jiangsu 215123, China.
authors.forename: Tengfei
authors.initials: T
authors.lastname: Tian
authors.forename: Xiaoze
authors.initials: X
authors.lastname: Shi
authors.forename: Liang
authors.initials: L
authors.lastname: Cheng
authors.forename: Yinchan
authors.initials: Y
authors.lastname: Luo
authors.forename: Ziliang
authors.initials: Z
authors.lastname: Dong
authors.forename: Hua
authors.initials: H
authors.lastname: Gong
authors.forename: Ligeng
authors.initials: L
authors.lastname: Xu
authors.forename: Zengtao
authors.initials: Z
authors.lastname: Zhong
authors.forename: Rui
authors.initials: R
authors.lastname: Peng
authors.forename: Zhuang
authors.initials: Z
authors.lastname: Liu
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D006108:Graphite / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D017348:Microscopy, Electron, Scanning Transmission; D053761:Nanocomposites; D059027:Recycling; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D006108:Graphite