title: Guillain-Barre syndrome after lung lobectomy: is there any relationship?
abstract: Guillain-Barré syndrome (GBS) is an acute inflammatory polyradiculopathy frequently triggered by infection. It has also been reported in some cases after surgical procedures. We describe the first case of GBS occurring 9 days after lung lobectomy for localized lung cancer and efficiently treated with intravenous immunoglobulins. The exact physiopathology of GBS after surgical procedures is unknown. An immune-mediated process and perioperative infection are the most accepted etiologic hypotheses.
authors.affiliation: Department of Thoracic Oncology, Pleural Diseases, and Interventional Pulmonology, Hôpital Nord, Marseille, France.
authors.forename: Jérôme
authors.initials: J
authors.lastname: Plojoux
authors.affiliation: Department of Thoracic Oncology, Pleural Diseases, and Interventional Pulmonology, Hôpital Nord, Marseille, France.
authors.forename: Marine
authors.initials: M
authors.lastname: Buffard-Morel
authors.affiliation: Department of Thoracic Oncology, Pleural Diseases, and Interventional Pulmonology, Hôpital Nord, Marseille, France.
authors.forename: Diane
authors.initials: D
authors.lastname: Ducamp
authors.affiliation: Department of Thoracic Oncology, Pleural Diseases, and Interventional Pulmonology, Hôpital Nord, Marseille, France; School of Medicine, Aix-Marseille University, Marseille, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Laroumagne
authors.affiliation: Department of Thoracic Oncology, Pleural Diseases, and Interventional Pulmonology, Hôpital Nord, Marseille, France; School of Medicine, Aix-Marseille University, Marseille, France.
authors.forename: Hervé
authors.initials: H
authors.lastname: Dutau
authors.affiliation: Department of Neurology and Neuromuscular Diseases, La Timone, Marseille, France; School of Medicine, Aix-Marseille University, Marseille, France.
authors.forename: Aude-Marie
authors.initials: AM
authors.lastname: Grapperon
authors.affiliation: Thoracic Surgery Department, Marseille Lung Transplant Group, Hôpital Nord, Marseille, France; School of Medicine, Aix-Marseille University, Marseille, France.
authors.forename: Pascal
authors.initials: P
authors.lastname: Thomas
authors.affiliation: Department of Thoracic Oncology, Pleural Diseases, and Interventional Pulmonology, Hôpital Nord, Marseille, France; School of Medicine, Aix-Marseille University, Marseille, France. Electronic address: philippejean.astoul@ap-hm.fr.
authors.forename: Philippe J
authors.initials: PJ
authors.lastname: Astoul
mesh_terms: D000369:Aged, 80 and over; D005500:Follow-Up Studies; D020275:Guillain-Barre Syndrome / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008175:Lung Neoplasms / Q000276:immunology / Q000473:pathology / Q000601:surgery*; D008297:Male; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging / Q000379:methods; D011013:Pneumonectomy / Q000009:adverse effects* / Q000379:methods; D011183:Postoperative Complications / Q000175:diagnosis / Q000628:therapy; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D020775:Thoracic Surgery, Video-Assisted / Q000009:adverse effects* / Q000379:methods; D016896:Treatment Outcome
chemical_list: D016756:Immunoglobulins, Intravenous