title: Alopecia universalis, renal stones, and hyperuricemia: a familial or an unfamiliar association.
abstract: Alopecia Universalis is an autoimmune disorder which sometimes may be associated with other autoimmune diseases like vitiligo, atopic dermatitis and endocrine disorders like hypothyroidism. In less than 2% of cases it may be associated with nephrotic syndrome although the underlying etiology has not been reported. We report here one similar case that had alopecia universalis beginning at the age of 17 years and simultaneously developed hyperuricemia. His son also developed alopecia universalis and renal stones at an early age of 10 years. The case represents one of the rare forms of alopecia namely alopecia universalis in two generations of the same family. Apart from this the case highlights the presence of renal stones probably due to hyperuricemia in both the generations which invokes a need to investigate any association of hyperuricemia with alopecia universalis.
authors.affiliation: Departments of Medicine, Postgraduate Institute of Medical Education and Research, Dr. Ram Manohar Lohia Hospital, New Delhi, India.
authors.forename: Kalachand
authors.initials: K
authors.lastname: Jana
authors.affiliation: Department of Medicine, Lady Hardinge Medical College and Associated Smt. S.K. Hospital, New Delhi, India.
authors.forename: Arun Shivajirao
authors.initials: AS
authors.lastname: Bade
authors.affiliation: Department of Medicine, Lady Hardinge Medical College and Associated Smt. S.K. Hospital, New Delhi, India.
authors.forename: Sachin Kumar
authors.initials: SK
authors.lastname: Jain
authors.affiliation: Department of Medicine, Lady Hardinge Medical College and Associated Smt. S.K. Hospital, New Delhi, India.
authors.forename: Ramesh
authors.initials: R
authors.lastname: Aggarwal
authors.affiliation: Department of Medicine, Lady Hardinge Medical College and Associated Smt. S.K. Hospital, New Delhi, India.
authors.forename: Aditya
authors.initials: A
authors.lastname: Dutta
keywords: Alopecia universalis; hyperuricemia; hypothyroidism; nephrotic syndrome