title: Risk factors of postoperative nosocomial pneumonia in stage I-IIIa lung cancer patients.
abstract: BACKGROUND
  To investigate the related risk factors of postoperative nosocomial pneumonia (POP) in patients with I-IIIa lung cancer.
  
  
  METHODS
  Medical records of 511 patients who underwent resection for lung cancer between January 2012 to December 2012 were retrospectively reviewed. Risk factors of postoperative pneumonia were identified and evaluated by univariate and multivariate analyses.
  
  
  RESULTS
  The incidence of postoperative pneumonia in these lung cancer patients was 2.9% (15 cases). Compared with 496 patients who had no pneumonia infection after operation, older age (>60), histopathological type of squamous cell carcinoma and longer surgery time (>3h) were significant risk factors by univariate analysis. Other potential risk factors such as alcohol consumption, history of smoking, hypersensitivity, hypertension, diabetes mellitus and so on were not showed such significance in this study. Further, the multivariate analysis revealed that old age (>60 years) (OR 5.813, p=0.018) and histopathological type of squamous cell carcinoma (OR 5.831, p<0.001) were also statistically significant independent risk factors for postoperative pneumonia.
  
  
  CONCLUSIONS
  This study demonstrated that being old aged (>60 years) and having squamous cell carcinoma histopathological type might be important factors in determining the risk of postoperative pneumonia in lung cancer patients after surgery.
authors.affiliation: Department of pharmacy, Zhejiang cancer hospital, Hangzhou, China E-mail : lnm1013@163.com.
authors.forename: Zeng
authors.initials: Z
authors.lastname: Wang
authors.forename: Xin-Jun
authors.initials: XJ
authors.lastname: Cai
authors.forename: Liang
authors.initials: L
authors.lastname: Shi
authors.forename: Fei-Yan
authors.initials: FY
authors.lastname: Li
authors.forename: Neng-Ming
authors.initials: NM
authors.lastname: Lin
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D003428:Cross Infection; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011014:Pneumonia / Q000453:epidemiology* / Q000401:mortality; D011183:Postoperative Complications / Q000453:epidemiology* / Q000401:mortality; D012189:Retrospective Studies; D012307:Risk Factors