title: An endobronchial inflammatory myofibroblastic tumor in a 10-yr-old child after allogeneic hematopoietic cell transplantation.
abstract: IMTs belong to the group of soft tissue tumor and could occur at any anatomical site; however, the causes and growth feature remain unclear. This case report documents a 10-yr-old male suffering from slowly developing dyspnea on exertion and cough around seven months post-HCT. He was diagnosed with an endobronchial tumor based on imaging, and histology confirmed ALK-positive submucosal spindle-shaped cells with infiltrative cells, compatible with IMT. We should be aware that IMT is a potential complication of pediatric allogeneic HCT and can cause sudden airway obstruction.
authors.affiliation: Department of Pediatrics, Osaka Red Cross Hospital, Osaka, Japan.
authors.forename: Hisanori
authors.initials: H
authors.lastname: Fujino
authors.forename: Young-Dong
authors.initials: YD
authors.lastname: Park
authors.forename: Suguru
authors.initials: S
authors.lastname: Uemura
authors.forename: Shinzo
authors.initials: S
authors.lastname: Tanaka
authors.forename: Masakazu
authors.initials: M
authors.lastname: Kawabe
authors.forename: Sayaka
authors.initials: S
authors.lastname: Maeda
authors.forename: Itaru
authors.initials: I
authors.lastname: Kato
authors.forename: Ken-Ichiro
authors.initials: K
authors.lastname: Watanabe
authors.forename: Katsutsugu
authors.initials: K
authors.lastname: Umeda
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Hiramatsu
authors.forename: Souichi
authors.initials: S
authors.lastname: Adachi
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Sato
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Date
authors.forename: Hironori
authors.initials: H
authors.lastname: Haga
authors.forename: Shinichi
authors.initials: S
authors.lastname: Sumimoto
mesh_terms: D016026:Bone Marrow Transplantation / Q000009:adverse effects; D001980:Bronchi / Q000473:pathology; D001984:Bronchial Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D002648:Child; D003371:Cough; D004724:Endoscopy; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D007249:Inflammation; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000628:therapy*; D012983:Soft Tissue Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014184:Transplantation, Homologous / Q000009:adverse effects*; D016896:Treatment Outcome
keywords: bone marrow transplantation; lung diseases