title: New frontiers in pediatric Allo-SCT.
abstract: The inaugural meeting of 'New Frontiers in Pediatric Allogeneic Stem Cell Transplantation' organized by the Pediatric Blood and Transplant Consortium (PBMTC) was held at the American Society of Pediatric Hematology and Oncology Annual Meeting. This meeting provided an international platform for physicians and investigators active in the research and utilization of pediatric Allo-SCT in children and adolescents with malignant and non-malignant disease (NMD), to share information and develop future collaborative strategies. The primary objectives of the conference included: (1) to present advances in Allo-SCT in pediatric ALL and novel pre and post-transplant immunotherapy; (2) to highlight new strategies in alternative allogeneic stem cell donor sources for children and adolescents with non-malignant hematological disorders; (3) to discuss timing of immune reconstitution after Allo-SCT and methods of facilitating more rapid recovery of immunity; (4) to identify strategies of utilizing Allo-SCT in pediatric myeloproliferative disorders; (5) to develop diagnostic and therapeutic approaches to hematological complications post pediatric Allo-SCT; (6) to enhance the understanding of new novel cellular therapeutic approaches to pediatric malignant and non-malignant hematological disorders; and (7) to discuss optimizing drug therapy in pediatric recipients of Allo-SCT. This paper will provide a brief overview of the conference.
authors.affiliation: Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Talano
authors.affiliation: Department of Pediatrics, University of Utah, Salt Lake City, UT, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Pulsipher
authors.affiliation: Department of Oncology, Johns Hopkins Hospital, Baltimore, MD, USA.
authors.forename: H J
authors.initials: HJ
authors.lastname: Symons
authors.affiliation: Department of Pediatrics, New York Medical College, Valhalla, NY, USA.
authors.forename: O
authors.initials: O
authors.lastname: Militano
authors.affiliation: Oregon Health and Science University, Portland, OR, USA.
authors.forename: E B
authors.initials: EB
authors.lastname: Shereck
authors.affiliation: Children's Hospital Colorado, Aurora, CO, USA.
authors.forename: R H
authors.initials: RH
authors.lastname: Giller
authors.affiliation: Pediatric Blood and Marrow Transplant Consortium, Monrovia, CA, USA.
authors.forename: L
authors.initials: L
authors.lastname: Hancock
authors.affiliation: Department of Pediatrics, New York Medical College, Valhalla, NY, USA.
authors.forename: E
authors.initials: E
authors.lastname: Morris
authors.affiliation: 1] Department of Pediatrics, New York Medical College, Valhalla, NY, USA [2] Department of Medicine, New York Medical College, Valhalla, NY, USA [3] Department of Pathology, New York Medical College, Valhalla, NY, USA [4] Department of Microbiology and Immunology, New York Medical College, Valhalla, NY, USA [5] Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, USA.
authors.forename: M S
authors.initials: MS
authors.lastname: Cairo
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D006801:Humans; D010372:Pediatrics / Q000379:methods; D033581:Stem Cell Transplantation / Q000379:methods*; D014184:Transplantation, Homologous