title: Tympanometric changes and eustachian tube function in patients with hypothyroidism.
abstract: OBJECTIVE
  The aim of this study was to investigate the tympanometric changes and eustachian tube function (ETF) in patients with hypothyroidism.
  
  
  METHODS
  Automatic ETF tests were performed and tympanometric measurements were evaluated to assess ETF in 40 patients diagnosed with hypothyroidism and a 40-patient euthyroid control group. Levothyroxine sodium tablet treatment was started in patients with hypothyroidism. After achieving a euthyroid state in these patients, the tympanometric measurements and automatic ETF tests were repeated.
  
  
  RESULTS
  When the patient groups (hypothyroid and control) were compared in terms of ETF, a statistically significant ET dysfunction was observed in the hypothyroid patient group (P < 0.01).When hypothyroid patients were evaluated in terms of ETF before and after treatment, whereas 61.3% of cases had ET function before treatment, this ratio increased to 78.8% after treatment. Furthermore, according to pressure and compliance measurements, statistically significant increases were found in the after treatment measurements (P < 0.05).
  
  
  CONCLUSIONS
  As a result of this study, we have come to the opinion that hypothyroidism can change tympanometric measurements and also cause ET dysfunction. However, more comprehensive and detailed studies researching the effects of hypothyroidism on tympanometric measurements are needed.
authors.affiliation: From the Departments of *Ear Nose and Throat and †Internal Medicine, Istanbul Medipol University, Istanbul; and ‡Training and Research Hospital Department of ENT, Elazig, Turkey.
authors.forename: Israfil
authors.initials: I
authors.lastname: Orhan
authors.forename: Fatih
authors.initials: F
authors.lastname: Palit
authors.forename: Salih
authors.initials: S
authors.lastname: Aydin
authors.forename: Erkan
authors.initials: E
authors.lastname: Soylu
authors.forename: Oner
authors.initials: O
authors.lastname: Sakallioglu
mesh_terms: D000158:Acoustic Impedance Tests / Q000379:methods*; D000293:Adolescent; D000328:Adult; D000368:Aged; D003187:Compliance; D003679:Deglutition / Q000502:physiology; D004427:Ear Diseases / Q000209:etiology / Q000503:physiopathology; D005064:Eustachian Tube / Q000503:physiopathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007037:Hypothyroidism / Q000188:drug therapy / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011312:Pressure; D013972:Thyrotropin / Q000032:analysis; D013974:Thyroxine / Q000627:therapeutic use; D014636:Valsalva Maneuver; D055815:Young Adult
chemical_list: D013972:Thyrotropin; D013974:Thyroxine