title: Chemotherapy for oral and maxillofacial tumors: an update.
abstract: Surgery is the primary intervention in oral and maxillofacial tumors and under ideal circumstances is curative. There is no evidence to support the use of induction or adjuvant chemotherapy in initial therapy of early stage tumors. Locally advanced tumors, non-resectable tumors as well as recurrence in early stage disease, need a multi-modality therapeutic approach involving chemotherapy. Palliative chemotherapy plays an important role in the treatment patients with metastatic oral and maxillofacial tumors. Chemotherapy and targeted agents plays an important role in the treatment of patients with rare oral and maxillofacial tumors such as sarcomas, lymphomas, and giant cell tumors.
authors.affiliation: Department of General Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 0462, Houston, TX 77030, USA. Electronic address: aeid@mdanderson.org.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Eid
authors.affiliation: Internal Medicine, University of Texas Health Science Center at Houston, 6431 Fannin, Houston, TX 77030, USA.
authors.forename: Shuang
authors.initials: S
authors.lastname: Li
authors.affiliation: Oral & Maxillofacial Surgery, University of Texas Health Science Center at Houston, 6516 MD Anderson Boulevard, Houston, TX 77030, USA.
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Garza
authors.affiliation: Oral & Maxillofacial Surgery, University of Texas Health Science Center at Houston, 6516 MD Anderson Boulevard, Houston, TX 77030, USA.
authors.forename: Mark E
authors.initials: ME
authors.lastname: Wong
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000473:pathology; D017024:Chemotherapy, Adjuvant; D005153:Facial Neoplasms / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D009062:Mouth Neoplasms / Q000188:drug therapy* / Q000473:pathology; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D010166:Palliative Care
chemical_list: D000970:Antineoplastic Agents
keywords: Chemotherapy; Locally advanced; Maxillofacial tumors; Oral cavity tumors; Squamous cell carcinoma