title: Mononucleosis-like drug rash: an interesting case presentation.
abstract: Dapsone hypersensitivity syndrome (DHS) is a rare adverse effect of the commonly prescribed drug dapsone. We present a case of a 35-year-old male who was referred to us from the gastroenterologist with complaints of rash, nausea, vomiting, and jaundice since 2 days with a provisional differential diagnosis of infectious mononucleosis or viral exanthema. On enquiry patient gave history of taking dapsone a week prior for refractory urticaria. After thorough investigations we diagnosed him with DHS. This syndrome occurs in a relatively small proportion of patients, but it is associated with considerable morbidity and mortality. The reason for presenting this case is to remind physicians of the unpredictability and potential severity of this reaction which makes it a major concern in clinical practice.
authors.affiliation: Department of Dermatology, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India.
authors.forename: Reshma T
authors.initials: RT
authors.lastname: Vishnani
authors.affiliation: Department of Dermatology, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India.
authors.forename: Ram H
authors.initials: RH
authors.lastname: Malkani
authors.affiliation: Department of Dermatology, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India.
authors.forename: Afsha A
authors.initials: AA
authors.lastname: Topal
authors.affiliation: Department of Gastroenterology, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India.
authors.forename: H G
authors.initials: HG
authors.lastname: Desai
keywords: Dapsone; dapsone hypersensitivity syndrome; mononucleosis-like drug rash