title: A single injection of intravitreal ranibizumab in the treatment of choroidal neovascularisation secondary to optic nerve head drusen in a child.
abstract: Optic nerve head drusen are acellular, calcified deposits which may be found in buried or exposed drusen form. Choroidal neovascularisation secondary to optic nerve head drusen is rarely seen in childhood. This case report summarises the clinical and therapeutic outcomes of a 13-year-old girl with unilateral choroidal neovascularisation secondary to optic nerve head drusen. The patient was successfully treated with a single intravitreal ranibizumab injection. After a month from the injection the visual acuity increased dramatically and maintained at the same level during 9 months of follow-up time. There was no complication related to the injection.
authors.affiliation: Beyoglu Eye Training and Research Hospital, Istanbul, Turkey.
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Alkin
authors.forename: Abdullah
authors.initials: A
authors.lastname: Ozkaya
authors.forename: Ihsan
authors.initials: I
authors.lastname: Yilmaz
authors.forename: Ahmet Taylan
authors.initials: AT
authors.lastname: Yazici
mesh_terms: D000293:Adolescent; D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use*; D020256:Choroidal Neovascularization / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D058449:Intravitreal Injections; D015594:Optic Disk Drusen / Q000150:complications*; D000069579:Ranibizumab; D020127:Recovery of Function; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D014792:Visual Acuity
chemical_list: D020533:Angiogenesis Inhibitors; D061067:Antibodies, Monoclonal, Humanized; D000069579:Ranibizumab