title: Pretibial Myxedema: Case Presentation and Review of Treatment Options.
abstract: Pretibial myxedema (PM) is a rare autoimmune manifestation of Graves' disease, which commonly presents as diffuse, nonpitting edema of shins and less often as plaques, nodules, or elephantiasis lesions mimicking lymphedema. We present a 57-year-old woman with 12-month history of PM, which occurred a year after treatment of Graves' disease and improved with topical corticosteroids, support stockings, and intralesional steroid injections until recurrence with local erythema and woody edema. A literature review was undertaken of the evidence-based treatment modalities for symptomatic PM: although commonly asymptomatic and self-limited, severe cases of PM may be treated with topical corticosteroid, compressive therapy, and intralesional corticosteroid injections.
authors.affiliation: McMaster University, Hamilton, Ontario, Canada whan.kim@medportal.ca.
authors.forename: Whan B
authors.initials: WB
authors.lastname: Kim
authors.affiliation: University of Toronto, Toronto, Ontario, Canada.
authors.forename: Nisha
authors.initials: N
authors.lastname: Mistry
authors.affiliation: University of Toronto, Toronto, Ontario, Canada.
authors.forename: Afsaneh
authors.initials: A
authors.lastname: Alavi
authors.affiliation: University of Toronto, Toronto, Ontario, Canada.
authors.forename: Cathryn
authors.initials: C
authors.lastname: Sibbald
authors.affiliation: University of Toronto, Toronto, Ontario, Canada.
authors.forename: Ronald G
authors.initials: RG
authors.lastname: Sibbald
keywords: case presentation; pretibial myxedema; thyroid dermopathy; treatment