title: Migration of bisphenol A into canned tomatoes produced in Italy: dependence on temperature and storage conditions.
abstract: A method based on solid-phase extraction followed by liquid chromatography, coupled to UV-visible and fluorescence spectrophotometry, has been developed for determination of bisphenol A (BPA) in canned tomatoes. The limit of quantification (LOQ) of the procedure used is 0.03 μM (0.26 μg BPA/kg tomato). For each of three different tomato based products (peeled, cherry and concentrated paste), 16 samples belonging to six commercial brands, retailed in Italian markets, were tested for migration of BPA epoxy-coating cans. All the tomato samples exhibited migration levels below 0.4 μg/kg, while samples subjected to heating process and/or can's damage by denting, exhibited a significant increase in the migration levels. In any case, no sample contained BPA exceeding the European Union limit for migration, set at 600 μg/kg of food. By comparing the results for each brand, no relevant difference in BPA concentration was found depending on the kind of tomato products.
authors.affiliation: National Laboratory on Endocrine Disruptors, National Institute of Biostructures and Biosystems (INBB), Via P. Castellino, 111, 80131 Naples, Italy; Department of Experimental Medicine, Second University of Naples, Via S.M. di Costantinopoli, 16, 80138 Naples, Italy.
authors.forename: Sonia
authors.initials: S
authors.lastname: Errico
authors.affiliation: National Laboratory on Endocrine Disruptors, National Institute of Biostructures and Biosystems (INBB), Via P. Castellino, 111, 80131 Naples, Italy; Dipartimento di Chimica, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via della Salute 2, 80055 Portici (NA), Italy.
authors.forename: Mariangela
authors.initials: M
authors.lastname: Bianco
authors.affiliation: National Laboratory on Endocrine Disruptors, National Institute of Biostructures and Biosystems (INBB), Via P. Castellino, 111, 80131 Naples, Italy; Dipartimento di Chimica, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via della Salute 2, 80055 Portici (NA), Italy.
authors.forename: Luigi
authors.initials: L
authors.lastname: Mita
authors.affiliation: National Laboratory on Endocrine Disruptors, National Institute of Biostructures and Biosystems (INBB), Via P. Castellino, 111, 80131 Naples, Italy; Department of Experimental Medicine, Second University of Naples, Via S.M. di Costantinopoli, 16, 80138 Naples, Italy.
authors.forename: Marina
authors.initials: M
authors.lastname: Migliaccio
authors.affiliation: Institute of Genetic and Biophysics "ABT", Via P. Castellino, 111, 80131 Naples, Italy.
authors.forename: Sergio
authors.initials: S
authors.lastname: Rossi
authors.affiliation: National Laboratory on Endocrine Disruptors, National Institute of Biostructures and Biosystems (INBB), Via P. Castellino, 111, 80131 Naples, Italy; Department of Experimental Medicine, Second University of Naples, Via S.M. di Costantinopoli, 16, 80138 Naples, Italy; Department of Experimental Medicine, Università degli Studi di Messina, AOU Policlinico G. Martino, Viale Gazzi, 98122 Messina, Italy.
authors.forename: Carla
authors.initials: C
authors.lastname: Nicolucci
authors.affiliation: National Laboratory on Endocrine Disruptors, National Institute of Biostructures and Biosystems (INBB), Via P. Castellino, 111, 80131 Naples, Italy; Department of Experimental Medicine, Second University of Naples, Via S.M. di Costantinopoli, 16, 80138 Naples, Italy; Institute of Genetic and Biophysics "ABT", Via P. Castellino, 111, 80131 Naples, Italy.
authors.forename: Ciro
authors.initials: C
authors.lastname: Menale
authors.affiliation: Department of Experimental Medicine, Second University of Naples, Via S.M. di Costantinopoli, 16, 80138 Naples, Italy.
authors.forename: Marianna
authors.initials: M
authors.lastname: Portaccio
authors.affiliation: Dipartimento di Chimica, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via della Salute 2, 80055 Portici (NA), Italy.
authors.forename: Pasquale
authors.initials: P
authors.lastname: Gallo
authors.affiliation: National Laboratory on Endocrine Disruptors, National Institute of Biostructures and Biosystems (INBB), Via P. Castellino, 111, 80131 Naples, Italy; Dipartimento di Chimica, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via della Salute 2, 80055 Portici (NA), Italy; Institute of Genetic and Biophysics "ABT", Via P. Castellino, 111, 80131 Naples, Italy. Electronic address: mita@igb.cnr.it.
authors.forename: Damiano G
authors.initials: DG
authors.lastname: Mita
authors.affiliation: National Laboratory on Endocrine Disruptors, National Institute of Biostructures and Biosystems (INBB), Via P. Castellino, 111, 80131 Naples, Italy; Dipartimento di Chimica, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via della Salute 2, 80055 Portici (NA), Italy; Institute of Genetic and Biophysics "ABT", Via P. Castellino, 111, 80131 Naples, Italy.
authors.forename: Nadia
authors.initials: N
authors.lastname: Diano
mesh_terms: D001559:Benzhydryl Compounds / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D002853:Chromatography, Liquid; D005062:European Union; D005506:Food Contamination / Q000032:analysis; D005519:Food Preservation / Q000379:methods*; D057141:Food, Preserved / Q000032:analysis*; D007558:Italy; D018551:Solanum lycopersicum / Q000737:chemistry*; D008452:Maximum Allowable Concentration; D010636:Phenols / Q000032:analysis*; D052616:Solid Phase Extraction / Q000379:methods; D013696:Temperature; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D010636:Phenols; C006780:bisphenol A; D000098826:Bisphenol A Compounds
keywords: Bisphenol A; Canned tomatoes; HPLC; Migration; Solid-phase extraction