title: Pull-out bond strength of a self-adhesive resin cement to NaOCl-treated root dentin: effect of antioxidizing agents.
abstract: OBJECTIVE
  This study evaluated the effect of three antioxidizing agents on pull-out bond strengths of dentin treated with sodium hypochlorite.
  
  
  METHODS
  Root canals of 75 single-rooted human teeth were prepared. Fifteen teeth were irrigated with normal saline for a negative control group, and the remaining 60 teeth (groups 2 - 5) with 2.5% NaOCl. The teeth in group 2 served as a positive control. Prior to post cementation, the root canals in groups 3 - 5 were irrigated with three antioxidizing agents including 10% rosmarinic acid (RA, Baridge essence), 10% hesperidin (HPN, Sigma), and 10% sodium ascorbate hydrogel (SA, AppliChem). Seventy-five spreaders (#55, taper .02, Produits Dentaires S.A) were coated with silica and silanized with the Rocatec system and ceramic bond. All the prepared spreaders were cemented with a self-adhesive resin cement (Bifix SE, Voco Gmbh) in the prepared canals. After storage in distilled water (24 h/37℃), the spreaders were pulled out in a universal testing machine at a crosshead speed of 1.0 mm/min. Pull-out strength values were analyzed by one-way ANOVA and Tukey's HSD test (α = 0.05).
  
  
  RESULTS
  There were significant differences between study groups (p = 0.016). The highest pull-out strength was related to the SA group. The lowest strength was obtained in the positive control group.
  
  
  CONCLUSIONS
  Irrigation with NaOCl during canal preparation decreased bond strength of resin cement to root dentin. Amongst the antioxidants tested, SA had superior results in reversing the diminishing effect of NaOCl irrigation on the bond strength to root dentin.
authors.affiliation: Dental Materials Research Center and Department of Operative Dentistry, Isfahan University of Medical Sciences School of Dentistry, Isfahan, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Khoroushi
authors.affiliation: Dental Students Research Center, Isfahan University of Medical Sciences School of Dentistry, Isfahan, Iran.
authors.forename: Marzieh
authors.initials: M
authors.lastname: Kachuei
keywords: Antioxidant; Bond strength; Endodontically treated teeth; Resin cement