title: Human Bocavirus in Iranian children with acute gastroenteritis.
abstract: BACKGROUND
  Human Bocavirus (HBoV) infection is of worldwide distribution. There is increasing evidencethat HBoV is pathogenic for the human gastroenteric tract. However, less data are available on the role of HBoVin gastroenteritis. The present study was aimed to determine the prevalence of HBoV in children with gastroenteritis.
  
  
  METHODS
  Real-time PCR TaqMan was used to screen 200 stool specimens that had been referred to the virologylaboratory for HBoV evaluation. All of samples were collected on viral transport media.
  
  
  RESULTS
  Of the 200 stool samples analyzed, 16 (8%) were positive for HBoV. Human Bocavirus positive samplesfrom patients aged between 1 to 5 years with acute gastroenteritis infection suggest a minor role of HBoVin gastroenteritis (p=0.0001).
  
  
  CONCLUSIONS
  The study showed a high prevalence of human Bocavirus in young children with acute gastroenteritisdiseases in Iran, suggesting that HBoV play a role in the pathogenesis of gastroenteritis.
authors.affiliation: PhD, Associate professor, Department of Virology and Anti-Microbial Resistance Research Center, Tehran University of Medical Sciences, Hemmat Highway, Tehran, Iran. hrmonavari@yahoo.com.
authors.forename: Seyed Hamidreza
authors.initials: SH
authors.lastname: Monavari
authors.affiliation: Professor of Pediatric Infectious Diseases, Research Center of Pediatric Infectious Diseases, Tehran University of Medical Sciences, Tehran, Iran. samileh_noorbakhsh @yahoo.com.
authors.forename: Samileh
authors.initials: S
authors.lastname: Noorbakhsh
authors.affiliation: PhD student, Department of Virology, Tehran University of Medical Sciences, Tehran, Iran. hamid2008kmu@gmail.com.
authors.forename: Hamidreza
authors.initials: H
authors.lastname: Mollaie
authors.affiliation: PhD student, Department of Virology, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Fazlalipour
authors.affiliation: Assistant professor, Human Viral Vaccine Department, Razi Vaccine & Serum Research Institute, Karaj, Iran.
authors.forename: Bahman
authors.initials: B
authors.lastname: Abedi Kiasari
keywords: Child; Gastroenteritis; Human Bocavirus; Real-time PCR