title: [Allergen detection among 2 769 children with allergic symptoms in Ningbo area].
abstract: A total of 2 769 children with allergic disease were admitted from October 2010 to December in Ningbo Women & Children's Hospital. Fourteen kinds of serum specific-IgE were detected by immunoblotting method. Among the 2 769 children, the total positive rate of sIgE was 76.0% (2 105/2 769). The sIgE positive rate in males (80.0%, 1 344/1 679) was significantly higher than that of females (69.8%, 761/1 090)(P < 0.05). The top three allergens were dust mites (33.2%), milk (12.6%) and fungi (12.6%). There were statistical differences of positive reaction to dust mites among 4 seasons (19.4%, 33.9%, 39.3%, 36.0%) (P < 0.05). Significant differences were found in the positive rates of dust mites, milk, fungi, and egg among the age groups (P < 0.05). The level of dust mite specific IgE were mainly in grade 3-6 (613/918, 66.8%).
authors.forename: Wen-Yuan
authors.initials: WY
authors.lastname: Liu
authors.forename: Jiang-Jin
authors.initials: JJ
authors.lastname: Zhou
mesh_terms: D000485:Allergens / Q000032:analysis*; D000818:Animals; D039741:Antigens, Dermatophagoides / Q000276:immunology; D000946:Antigens, Fungal / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis*; D007073:Immunoglobulin E / Q000097:blood; D007223:Infant; D008297:Male; D008892:Milk / Q000276:immunology
chemical_list: D000485:Allergens; D039741:Antigens, Dermatophagoides; D000946:Antigens, Fungal; D007073:Immunoglobulin E