title: [Mics of the Clostridium thermocellum in lignocellulose degradation--a review].
abstract: Clostridium thermocellum ( C. thermocellum ) is the dominant microorganism that can efficiently degrade lignocellulose. Extensive studies were done for secreting the cell surface-bound protein complex known as the cellulosome. C. thermocellum is regulated by carbon sources, reflected in overall multiple cellulase production and in the cellulosomal subunit profile. To produce a cellulosomal protein complex is a dynamic assembly process. In recent years, it becomes a hotspot to study how C. thermocellum senses the insoluble substrate, regulates the secretion of relevant enzymes, and assembles the supramolecular-degradation enzyme complex. This review summarized the research advance in genomics, transcriptomics, proteomics and extracellular carbohydrate-sensing mechanism in C. thermocellum, and analyzed the mechanism and dynamic process of C. thermocellum in lignocellulose degradation.
authors.forename: Lin
authors.initials: L
authors.lastname: Chen
authors.forename: Lushan
authors.initials: L
authors.lastname: Wang
authors.forename: Huaiqiang
authors.initials: H
authors.lastname: Zhang
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D001673:Biodegradation, Environmental; D048013:Acetivibrio thermocellus / Q000201:enzymology / Q000235:genetics / Q000378:metabolism*; D008031:Lignin / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; C036909:lignocellulose; D008031:Lignin