title: Bowel preparation regimens for colon capsule endoscopy: a review.
abstract: Colon capsule endoscopy (CCE) is being actively evaluated as an emerging complementary or alternative procedure for evaluation of the colon. The yield of CCE is significantly dependent on the quality of bowel preparation. In addition to achieving a stool-free colon the bowel preparation protocols need to decrease bubble effect and aid propulsion of the capsule. An extensive English literature search was done using PubMed with search terms of colon capsule endoscopy, PillCam and bowel preparation. Full-length articles which met the criteria were included for review. A total of 12 studies including 1149 patients were reviewed. There was significant variability in the type of bowel preparation regimens. Large-volume (3-4 liters) polyethylene glycol (PEG) was the most widely used laxative. Lower volumes of PEG showed comparable results but larger studies are needed to determine efficacy. Sodium phosphate was used as an effective booster in most studies. Magnesium citrate and ascorbic acid are emerging as promising boosters to replace sodium phosphate when it is contraindicated. The potential benefit of prokinetics needs further evaluation. Over the past decade there has been significant improvement in the bowel preparation regimens for CCE. Further experience and studies are likely to standardize the bowel preparation regimens before CCE is adopted into routine clinical practice.
authors.affiliation: Division of Digestive and Liver Diseases, Columbia University Medical Center, New York Presbyterian Hospital, 5141 Broadway, New York, NY 10034, USA.
authors.forename: Shashideep
authors.initials: S
authors.lastname: Singhal
authors.affiliation: Division of Gastroenterology and Hepatology, The Brooklyn Hospital Center, Brooklyn, New York, NY, USA.
authors.forename: Sofia
authors.initials: S
authors.lastname: Nigar
authors.affiliation: Division of Gastroenterology and Hepatology, The Brooklyn Hospital Center, Brooklyn, New York, NY, USA.
authors.forename: Vani
authors.initials: V
authors.lastname: Paleti
authors.affiliation: Division of Gastroenterology and Hepatology, The Brooklyn Hospital Center, Brooklyn, New York, NY, USA.
authors.forename: Devin
authors.initials: D
authors.lastname: Lane
authors.affiliation: Division of Gastroenterology and Hepatology, The Brooklyn Hospital Center, Brooklyn, New York, NY, USA.
authors.forename: Sushil
authors.initials: S
authors.lastname: Duddempudi
keywords: bowel preparation; capsule colonoscopy; regimens; review