title: [Research advances in the expression of co-stimulatory molecules and signaling pathways in γδT cells].
abstract: Human T lymphocytes are divided into αβT cells and γδT cells on the basis of the different expressions of T cell receptors. In recent years, the studies of the regulation of T cell activation and tolerance by co-stimulatory molecules and their signaling pathways in αβT cell have made remarkable progress; however, relatively fewer investigations have been performed on γδT cells. A clearer understanding of the roles of co-stimulatory molecules and their signaling pathways in the positive/negative regulation of γδT cells at different stages will provides new insights for the treatment of viral infections, cancer, autoimmune diseases, transplant rejection, and other conditions.
authors.affiliation: Key Laboratory of Jiaxing Second Hospital,Jiaxing, Zhejiang 314000,China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Bao
authors.affiliation: Key Laboratory of Jiaxing Second Hospital,Jiaxing, Zhejiang 314000,China.
authors.forename: Li
authors.initials: L
authors.lastname: Guo
mesh_terms: D006801:Humans; D008213:Lymphocyte Activation / Q000502:physiology*; D015398:Signal Transduction; D016176:T-Lymphocyte Subsets / Q000502:physiology*