title: Synthetic aspects, spectral, thermal studies and antimicrobial screening on bis(N,N-dimethyldithiocarbamato-S,S')antimony(III) complexes with oxo or thio donor ligands.
abstract: The bis(N,N-dimethyldithiocarbamato-S,S')antimony(III) complexes have been obtained by the reaction of chloro bis(N,N-dimethyldithiocarbamato-S,S')antimony(III) with corresponding oxo or thio donor ligands such as sodium benzoate 1, sodium thioglycolate 2, phenol 3, sodium 1-propanethiolate 4, potassium thioacetate 5, sodium salicylate 6, ethane-1,2-dithiolate 7 and disodium oxalate 8. These complexes have been characterized by the physicochemical [melting point, molecular weight determination and elemental analysis (C, H, N, S and Sb)], spectral [UV-Visible, FT-IR, far IR, NMR (1H and 13C)], thermogravimetric (TG & DTA) analysis, ESI-Mass and powder X-ray diffraction studies. Thermogravimetric analysis of the complexes confirmed the final decomposition product as highly pure antimony sulfide (Sb2S3) and powder X-ray diffraction studies show that the complexes are in lower symmetry with monoclinic crystal lattice and nano-ranged particle size (11.51-20.82 nm). The complexes have also been screened against some bacterial and fungal strains for their antibacterial and antifungal activities and compared with standard drugs. These show that the complexes have greater activities against some human pathogenic bacteria and fungi than the activities of standard drugs.
authors.affiliation: School of Chemical Sciences, Devi Ahilya University, Takshashila Campus, Khandwa Road, Indore 452001, India. Electronic address: hpsc@rediffmail.com.
authors.forename: H P S
authors.initials: HP
authors.lastname: Chauhan
authors.affiliation: School of Chemical Sciences, Devi Ahilya University, Takshashila Campus, Khandwa Road, Indore 452001, India.
authors.forename: Jaswant
authors.initials: J
authors.lastname: Carpenter
authors.affiliation: School of Chemical Sciences, Devi Ahilya University, Takshashila Campus, Khandwa Road, Indore 452001, India.
authors.forename: Sapana
authors.initials: S
authors.lastname: Joshi
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry*; D000965:Antimony / Q000737:chemistry*; D001234:Aspergillus niger / Q000187:drug effects; D001412:Bacillus subtilis / Q000187:drug effects; D002626:Chemistry, Pharmaceutical; D004583:Electrons; D004926:Escherichia coli / Q000187:drug effects; D006358:Hot Temperature; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D010316:Particle Size; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D015203:Reproducibility of Results; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013211:Staphylococcus aureus / Q000187:drug effects; D013438:Sulfhydryl Compounds; D013440:Sulfides / Q000737:chemistry; D013696:Temperature; D013818:Thermogravimetry; D014242:Trichoderma / Q000187:drug effects; D014961:X-Ray Diffraction
chemical_list: D000890:Anti-Infective Agents; D008024:Ligands; D013438:Sulfhydryl Compounds; D013440:Sulfides; D000965:Antimony
keywords: Antimicrobial; Antimony sulfide; Antimony(III); Dithiocarbamate; Powder XRD; Thermogravimetric