title: [Eye infections caused by Purpureocillium lilacinum: A case report and literature review].
abstract: BACKGROUND
  Purpureocillium lilacinum eye infections (previously called Paecilomyces lilacinus) make up a significant percentage of the recorded cases of infection by this fungus, and is considered as an emerging pathogen.
  
  
  OBJECTIVE
  To report a case of ocular mycosis in a patient aged 70, with a double corneal transplantation in the right eye, and exhibiting a poor response to antifungal and surgical treatment.
  
  
  METHODS
  Corneal ring and ocular tissues obtained by surgical procedures were cultured in common mycological media. Molecular identification of the isolated fungus was obtained.
  
  
  RESULTS
  Colonies of a filamentous fungus were obtained, and according to the macroscopic and microscopic morphology it was identified as P. lilacinum. The identification was confirmed by molecular methods in a reference laboratory.
  
  
  CONCLUSIONS
  Eye infections due to P. lilacinum are rare but serious diseases that requires rapid diagnostic and therapeutic measures to enable visual function to recover.
authors.affiliation: Sección de Microbiología, Hospital El Bierzo, Ponferrada, León, España. Electronic address: ramirozlm@ono.com.
authors.forename: Ramiro
authors.initials: R
authors.lastname: López-Medrano
authors.affiliation: Servicio de Oftalmología, Hospital El Bierzo, Ponferrada, León, España.
authors.forename: Alberto
authors.initials: A
authors.lastname: Pérez Madera
authors.affiliation: Sección de Microbiología, Hospital El Bierzo, Ponferrada, León, España.
authors.forename: Carlos
authors.initials: C
authors.lastname: Fuster Foz
mesh_terms: D000368:Aged; D000890:Anti-Infective Agents / Q000627:therapeutic use; D002387:Cataract Extraction; D060085:Coinfection; D016039:Corneal Transplantation; D003320:Corneal Ulcer / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D004271:DNA, Fungal / Q000235:genetics; D021903:DNA, Ribosomal Spacer / Q000235:genetics; D020605:Delftia acidovorans / Q000302:isolation & purification; D017234:Eye Evisceration; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000150:complications; D006563:Herpes Zoster Ophthalmicus / Q000150:complications; D006801:Humans; D006999:Hypocreales / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity*; D010143:Paecilomyces / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity*; D012086:Reoperation; D021521:Ribotyping; D013530:Surgical Wound Infection / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery
chemical_list: D000890:Anti-Infective Agents; D004271:DNA, Fungal; D021903:DNA, Ribosomal Spacer
keywords: Fungal keratitis; Infecciones oculares; Ocular infections; Paecilomyces lilacinus; Queratitis fúngicas