title: Chronic periapical lesions: correlations with clinical finding.
abstract: OBJECTIVE
  The aim of this study was to evaluate the relationship between periapical lesions with and without clinical symptoms.
  
  
  METHODS
  This study was performed on cases with chronic periapical lesion diagnosis. During oral surgery procedures, 80 tissue samples were obtained. Anamnesis data were taken from each subject included in the study. Periapical tissue samples were processed for laboratory procedures including: histological and pathological examination of lesions by light microscopy analysis and microbiological status assessment by qualitative and semi-quantitative analysis of bacteriological findings.
  
  
  CONCLUSIONS
  The results obtained illustrate that symptomatic apical periodontitis was more frequent with teeth without previous endodontic therapy. Even though a pathological type of periapical inflammation is significantly associated with the presence or absence of clinical symptoms (p=0.0002), they do not have an effect on making a clinical diagnosis. Statistical analysis showed no significant difference (p>0.05). Comparative analysis of symptom persistence and infection severity was performed. It was found that positive symptoms were in relation to the quantity of the bacterial growth only in the group previous endodontically treated and these two factors do show relation with an accuracy of 95%. The growth of a mixture of several, mainly anaerobic, bacterial species is closely related to the presence of clinical symptoms.
authors.affiliation: Department of Cariology and Endodontology, Faculty of Dentistry, Ss Cyril and Methodius University, Skopje, R. Macedonia.
authors.forename: Lidija
authors.initials: L
authors.lastname: Popovska
authors.forename: Efka
authors.initials: E
authors.lastname: Zabokova Bilbilova
authors.forename: Elena
authors.initials: E
authors.lastname: Mircheva
authors.forename: Vera
authors.initials: V
authors.lastname: Stojanovska
mesh_terms: D000293:Adolescent; D000328:Adult; D001421:Bacteria, Anaerobic / Q000302:isolation & purification*; D001424:Bacterial Infections / Q000175:diagnosis* / Q000382:microbiology; D003786:Dental Pulp Cavity / Q000382:microbiology / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D010485:Periapical Periodontitis / Q000175:diagnosis* / Q000382:microbiology; D010486:Periapical Tissue / Q000382:microbiology / Q000473:pathology*; D055815:Young Adult