title: Phosphorylated dendronized poly(amido amine)s as protein analogues for directing hydroxylapatite biomineralization.
abstract: Dendronized poly(amido amine)s (DPs) bearing tri-phosphate or bis-phosphonate peripheral groups are synthesized. These worm-like DPs can template the formation of BMSCs adhesive hydroxylapatite (HA) on the nano-scale, or self-assemble into mineral-collecting microfibers on the micro-scale, exhibiting similar functions of non-collagenous proteins (NCPs) in the natural biomineralization process of HA.
authors.affiliation: College of Polymer Science and Engineering, Sichuan University, Chengdu, China. jianshu_li@scu.edu.cn.
authors.forename: Jianyu
authors.initials: J
authors.lastname: Xin
authors.forename: Tianchan
authors.initials: T
authors.lastname: Chen
authors.forename: Zaifu
authors.initials: Z
authors.lastname: Lin
authors.forename: Ping
authors.initials: P
authors.lastname: Dong
authors.forename: Hong
authors.initials: H
authors.lastname: Tan
authors.forename: Jianshu
authors.initials: J
authors.lastname: Li
mesh_terms: D001854:Bone Marrow Cells / Q000166:cytology; D002448:Cell Adhesion / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D050091:Dendrimers / Q000737:chemistry*; D017886:Durapatite / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000166:cytology; D053758:Nanoparticles / Q000737:chemistry; D010766:Phosphorylation; D011073:Polyamines / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry
chemical_list: D050091:Dendrimers; C531249:Poly(amidoamine); D011073:Polyamines; D011506:Proteins; D017886:Durapatite