title: Intravitreal dexamethasone implant for acute exudative polymorphous vitelliform maculopathy.
abstract: OBJECTIVE
  Acute exudative polymorphous vitelliform maculopathy is a rare retinal disease characterized by bilateral serous macular detachment and subretinal accumulation of yellowish deposits resembling Best dystrophy lesions. Corticosteroid systemic therapy has been used empirically in the attempt to treat this retinal disorder with mixed results. Thus, the benefit of corticosteroid remains undetermined. To our knowledge, we report the first case of acute exudative polymorphous vitelliform maculopathy (AEPVM) treated in one eye with intravitreal dexamethasone implant (Ozurdex; Allergan, Inc., Irvine, California, USA).
  
  
  METHODS
  A 28-year-old man with AEPVM underwent intravitreal dexamethasone implantation in the left eye.
  
  
  RESULTS
  Compared with the fellow eye, intravitreal dexamethasone implant did not significantly modify the clinical course of the disease. No implant-related complication was experienced during follow-up.
  
  
  CONCLUSIONS
  The lack of response to intravitreal dexamethasone seems to suggest that corticosteroids may be ineffective for the treatment of AEPVM.
authors.affiliation: Department of Ophthalmology, Catholic University, Rome - Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Scupola
authors.forename: Edoardo
authors.initials: E
authors.lastname: Abed
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Sammarco
authors.forename: Salvatore
authors.initials: S
authors.lastname: Traina
authors.forename: Antonio
authors.initials: A
authors.lastname: Villano
authors.forename: Gabriela
authors.initials: G
authors.lastname: Grimaldi
authors.forename: Maria Antonietta
authors.initials: MA
authors.lastname: Blasi
mesh_terms: D000208:Acute Disease; D000328:Adult; D004396:Coloring Agents; D003907:Dexamethasone / Q000008:administration & dosage*; D004343:Drug Implants; D005122:Exudates and Transudates; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D057826:Vitelliform Macular Dystrophy / Q000175:diagnosis / Q000188:drug therapy*; D014822:Vitreous Body
chemical_list: D004396:Coloring Agents; D004343:Drug Implants; D005938:Glucocorticoids; D003907:Dexamethasone; D007208:Indocyanine Green