title: Modification of bipolar lipid conformation at the air/water interface by a single stereochemical variation.
abstract: This article describes the design and the synthesis of two analogues of archaeal bipolar lipids that differ only by the configuration of a single stereogenic centre on a glyceryl moiety. The corresponding comparative physicochemical study by tensiometry/ellipsometry and atomic force microscopy provided a set of data that points out the effect of this single stereochemical variation. The two epimers revealed different conformations at the air/water interface resulting in a more or less tendency for a bent or a stretched conformation. It strengthens the importance of the stereochemistry in such bipolar lipid packing.
authors.affiliation: Ecole Nationale Supérieure de Chimie de Rennes, CNRS, UMR 6226, 11 Allée de Beaulieu, CS 50837, 35708 Rennes Cedex 7, France; Université Européenne de Bretagne, France.
authors.forename: Nolwenn
authors.initials: N
authors.lastname: Terme
authors.affiliation: Ecole Nationale Supérieure de Chimie de Rennes, CNRS, UMR 6226, 11 Allée de Beaulieu, CS 50837, 35708 Rennes Cedex 7, France; Université Européenne de Bretagne, France.
authors.forename: Alicia
authors.initials: A
authors.lastname: Jacquemet
authors.affiliation: Ecole Nationale Supérieure de Chimie de Rennes, CNRS, UMR 6226, 11 Allée de Beaulieu, CS 50837, 35708 Rennes Cedex 7, France; Université Européenne de Bretagne, France.
authors.forename: Thierry
authors.initials: T
authors.lastname: Benvegnu
authors.affiliation: Institut de Physique de Rennes, Université Rennes 1, UMR-CNRS 6251, Campus Beaulieu Bat. 11A, 35042 Rennes Cedex, France; Université Européenne de Bretagne, France.
authors.forename: Véronique
authors.initials: V
authors.lastname: Vié
authors.affiliation: Ecole Nationale Supérieure de Chimie de Rennes, CNRS, UMR 6226, 11 Allée de Beaulieu, CS 50837, 35708 Rennes Cedex 7, France; Université Européenne de Bretagne, France. Electronic address: loic.lemiegre@ensc-rennes.fr.
authors.forename: Loïc
authors.initials: L
authors.lastname: Lemiègre
mesh_terms: D000388:Air; D008956:Models, Chemical; D008968:Molecular Conformation; D013253:Steroid 12-alpha-Hydroxylase; D013499:Surface Properties; D013501:Surface-Active Agents / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: D013501:Surface-Active Agents; D014867:Water; D013253:Steroid 12-alpha-Hydroxylase
keywords: Air/water interface; Archaea; Stereochemistry; Stretched/bent conformation; Tetraether lipid