title: Decontamination of materials contaminated with Francisella philomiragia or MS2 bacteriophage using PES-Solid, a solid source of peracetic acid.
abstract: OBJECTIVE
  The aim of the study was to develop test methods and evaluate survival of Francisella philomiragia cells and MS2 bacteriophage after exposure to PES-Solid (a solid source of peracetic acid) formulations with or without surfactants.
  
  
  RESULTS
  Francisella philomiragia cells (≥7·6 log10 CFU) or MS2 bacteriophage (≥6·8 log10 PFU) were deposited on seven different test materials and treated with three different PES-Solid formulations, three different preneutralized samples and filter controls at room temperature for 15 min. There were 0-1·3 log10 CFU (<20 cells) of cell survival, or 0-1·7 log10 (<51 PFU) of bacteriophage survival in all 21 test combinations (organism, formulation and substrate) containing reactive PES-Solid. In addition, the microemulsion (Dahlgren Surfactant System) showed ≤2 log10 (100 cells) of viable F. philomiragia cells, indicating the microemulsion achieved <2 log10 CFU on its own.
  
  
  CONCLUSIONS
  Three PES-Solid formulations and one microemulsion system (DSS) inactivated F. philomiragia cells and/or MS2 bacteriophage that were deposited on seven different materials.
  
  
  CONCLUSIONS
  A test method was developed to show that reactive PES-Solid formulations and a microemulsion system (DSS) inactivated >6 log10 CFU/PFU F. philomiragia cells and/or MS2 bacteriophage on different materials.
authors.affiliation: CBR Concepts and Experimentation Branch (Z21), Naval Surface Warfare Center, Dahlgren Division, Dahlgren, VA, USA.
authors.forename: T L
authors.initials: TL
authors.lastname: Buhr
authors.forename: A A
authors.initials: AA
authors.lastname: Young
authors.forename: C A
authors.initials: CA
authors.lastname: Johnson
authors.forename: Z A
authors.initials: ZA
authors.lastname: Minter
authors.forename: C M
authors.initials: CM
authors.lastname: Wells
mesh_terms: D003666:Decontamination / Q000379:methods*; D004202:Disinfectants / Q000494:pharmacology*; D004203:Disinfection / Q000379:methods*; D005603:Francisella / Q000187:drug effects*; D017909:Levivirus / Q000187:drug effects*; D050296:Microbial Viability / Q000187:drug effects; D010463:Peracetic Acid / Q000494:pharmacology*; D013501:Surface-Active Agents
chemical_list: D004202:Disinfectants; D013501:Surface-Active Agents; D010463:Peracetic Acid
keywords: F. philomiragia; MS2 bacteriophage; PES-Solid; decontamination; peracetic acid