title: Small cell lung carcinoma associated with progressive systemic sclerosis.
abstract: The association between progressive systemic sclerosis (PSS) and malignancy is uncommon. The possibility of development of small cell carcinoma lung (SCLC), among all the reported lung malignancies in PSS patients is lowest. A fifty-five year old non-smoker female diagnosed as PSS for 1 year presented to our outpatient department with dry cough for 2 months, shortness of breath for the last 1 month and progressive facial and right upper limb oedema for the last 15 days. Chest X-ray showed homogenous opacity in the right upper and mid zones of lung and the obliteration of both costophrenic angles. High resolution computed tomography (CT) of the thorax revealed a right upper lobe lung mass with bilateral minimal pleural effusion and the presence of bilateral reticular opacities, with basal predominance, associated with septal thickening, suggestive of interstitial lung disease of non-specific interstitial pneumonia pattern. CT guided fine needle aspiration cytology (FNAC) from the right upper lobe mass was suggestive of small cell carcinoma. Patient was improved after 6 cycles of chemotherapy with carboplatin and etoposide.
authors.affiliation: Department of Pulmonary Medicine, Burdwan Medical College, Burdwan, West Bengal, India.
authors.forename: Kaushik
authors.initials: K
authors.lastname: Saha
authors.affiliation: Department of Pulmonary Medicine, Burdwan Medical College, Burdwan, West Bengal, India.
authors.forename: Arnab
authors.initials: A
authors.lastname: Saha
authors.affiliation: Department of Pulmonary Medicine, Burdwan Medical College, Burdwan, West Bengal, India.
authors.forename: Prabodh
authors.initials: P
authors.lastname: Panchadhyayee
authors.affiliation: Department of Pulmonary Medicine, Burdwan Medical College, Burdwan, West Bengal, India.
authors.forename: Mrinmoy
authors.initials: M
authors.lastname: Mitra
authors.affiliation: Department of Pulmonary Medicine, Burdwan Medical College, Burdwan, West Bengal, India.
authors.forename: Tara Sankar
authors.initials: TS
authors.lastname: Malik
authors.affiliation: Department of Pulmonary Medicine, Burdwan Medical College, Burdwan, West Bengal, India.
authors.forename: Pratik
authors.initials: P
authors.lastname: Barma
authors.affiliation: Department of Pulmonary Medicine, Burdwan Medical College, Burdwan, West Bengal, India.
authors.forename: Santanu
authors.initials: S
authors.lastname: Ghosh
keywords: interstitial fibrosis; progressive systemic sclerosis; small cell lung carcinoma