title: Restless legs syndrome in multiple system atrophy.
abstract: The purpose of the study was to evaluate the frequency of restless legs syndrome in 30 patients with multiple system atrophy. Eight patients complained from restless legs syndrome, their severity score was 19.4 ± 4.1. Pittsburgh Sleep Quality Index scores were significantly higher in patients with restless legs syndrome than those without (9.3 ± 3.7 vs. 4.8 ± 2.9, p = 0.00165). Periodic limb movements were found in 75% of patients with restless legs syndrome. Restless legs syndrome is more prevalent in multiple system atrophy as compared to the acknowledged prevalence in the general population.
authors.affiliation: Department of Clinical Neurophysiology, CHU de Bordeaux, Place Amélie Raba-Léon, 33076, Bordeaux, France, imad.ghorayeb@u-bordeaux2.fr.
authors.forename: Imad
authors.initials: I
authors.lastname: Ghorayeb
authors.forename: Sandrine
authors.initials: S
authors.lastname: Dupouy
authors.forename: François
authors.initials: F
authors.lastname: Tison
authors.forename: Wassilios G
authors.initials: WG
authors.lastname: Meissner
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019578:Multiple System Atrophy / Q000150:complications* / Q000453:epidemiology*; D011569:Psychiatric Status Rating Scales; D012148:Restless Legs Syndrome / Q000150:complications* / Q000453:epidemiology*; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric