title: Unifocal Langerhans cell histiocytosis of the superior oblique muscle.
abstract: Orbital Langerhans cell histiocytosis (LCH) without bone involvement is rare. Isolated involvement of an extraocular muscle without bone change, to the best of the authors' knowledge, has not been previously reported. They describe a unique case of unifocal LCH of the superior oblique muscle with no bone involvement. A 16-year-old girl presented with a 2-week history of diplopia and headache. CT and MRI showed an enlarged right superior oblique muscle with no associated bone involvement. Biopsy with partial debulking revealed LCH and staging confirmed unifocal disease. The lesion underwent complete radiologic resolution following surgery. There was no recurrence after 16 months follow up.
authors.affiliation: *South Australian Institute of Ophthalmology and Discipline of Ophthalmology and Visual Sciences, University of Adelaide; †Department of Surgical Pathology, Institute of Medical and Veterinary Science, Royal Adelaide Hospital, Adelaide, South Australia; and ‡Department of Anatomical Pathology, St Vincent's Hospital, Melbourne, Victoria, Australia.
authors.forename: Daniel
authors.initials: D
authors.lastname: Narayan
authors.forename: Edwin
authors.initials: E
authors.lastname: Figueira
authors.forename: Daniel
authors.initials: D
authors.lastname: Kearney
authors.forename: Penelope
authors.initials: P
authors.lastname: McKelvie
authors.forename: Garry
authors.initials: G
authors.lastname: Davis
authors.forename: Dinesh
authors.initials: D
authors.lastname: Selva
mesh_terms: D000293:Adolescent; D001706:Biopsy; D004172:Diplopia / Q000175:diagnosis; D005260:Female; D006261:Headache / Q000175:diagnosis; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D009135:Muscular Diseases / Q000175:diagnosis* / Q000601:surgery; D009801:Oculomotor Muscles / Q000473:pathology*; D014057:Tomography, X-Ray Computed