title: Routine depression screening and diagnosing strategy for cancer inpatients.
abstract: BACKGROUND
  Clinical practice guidelines frequently recommend systematic screening for depression in cancer patients to improve recognition and prompt appropriate management. We aimed to screen major depressive disorder (MDD) in cancer inpatients using a structured tool and explore its applicability.
  
  
  METHODS
  Cancer inpatients were routinely screened by nurses using the Taiwanese Depression Questionnaire (TDQ), and for those screened positive, this was followed by a non-mandated referral to a psychiatrist for clinical evaluation and diagnosis. Patients who completed this two-stage procedure comprised the analysis sample.
  
  
  RESULTS
  Routine screening of 8800 patients in a period of 27 months yielded 1087 (26.9%) positive first-time screens. Of them, 298 (27.4%) completed the psychiatric consultation. Depressive disorders were diagnosed in 185 patients (62.1%), mainly adjustment disorder (23.8%) and MDD (21.5%). The estimated prevalence of MDD was 21.5%. Area under the curve was 0.72, a result produced by the receiver operating characteristic curve of the TDQ scores relative to the clinical psychiatric diagnoses of MDD. A TDQ cutoff score of ≧26 provided an optimal diagnostic accuracy for MDD.
  
  
  CONCLUSIONS
  This two-stage depression screening and diagnosing strategy is practical for improving recognition of MDD and other depressive disorders in cancer patients and could be routinely applied, rather than selectively, in a comprehensive cancer care system.
authors.affiliation: Department of Psychiatry, E-Da Hospital, Kaohsiung, Taiwan; Department of Nursing, College of Medicine, I-Shou University, Kaohsiung, Taiwan.
authors.forename: Chun-Hsien
authors.initials: CH
authors.lastname: Tu
authors.forename: Mei-Chi
authors.initials: MC
authors.lastname: Hsu
authors.forename: Shu-Ching
authors.initials: SC
authors.lastname: Chi
authors.forename: Hung-Yen
authors.initials: HY
authors.lastname: Lin
authors.forename: Yung-Chieh
authors.initials: YC
authors.lastname: Yen
mesh_terms: D000275:Adjustment Disorders / Q000175:diagnosis / Q000208:ethnology; D000328:Adult; D000368:Aged; D044466:Asian People / Q000523:psychology* / Q000706:statistics & numerical data; D003430:Cross-Sectional Studies; D003863:Depression / Q000175:diagnosis* / Q000208:ethnology; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000208:ethnology; D005260:Female; D006801:Humans; D007297:Inpatients; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D009369:Neoplasms / Q000523:psychology*; D015995:Prevalence; D011569:Psychiatric Status Rating Scales; D012372:ROC Curve; D011795:Surveys and Questionnaires; D013624:Taiwan / Q000453:epidemiology
keywords: Taiwanese Depression Questionnaire; cancer; diagnostic accuracy; major depressive disorder; routine depression screening