title: Complex sleep apnea associated with use of nasal expiratory positive airway (nEPAP) device.
abstract: Complex sleep apnea syndrome (CompSAS) is characterized by predominant obstructive sleep disordered breathing with evolution of central disordered breathing following exposure to nasal continuous positive airway pressure (CPAP) therapy in obstructive sleep apnea (OSA) patients. We report a case of CompSAS associated with use of a nasal expiratory positive airway (nEPAP, Provent) device. We therefore recommend obtaining objective sleep data to confirm treatment effectiveness of the nEPAP device for OSA prior to long-term prescription. Further research is warranted to understand the underlying pathophysiological mechanisms and risk factors associated with CompSAS.
authors.affiliation: Center for Sleep Medicine, Mayo Clinic, Rochester, MN.
authors.forename: Amit
authors.initials: A
authors.lastname: Chopra
authors.affiliation: Department of Sleep Medicine, Cleveland Clinic, Cleveland, OH.
authors.forename: Piyush
authors.initials: P
authors.lastname: Das
authors.affiliation: Center for Sleep Medicine, Mayo Clinic, Rochester, MN.
authors.forename: Kannan
authors.initials: K
authors.lastname: Ramar
authors.affiliation: Center for Sleep Medicine, Mayo Clinic, Rochester, MN.
authors.forename: Bruce
authors.initials: B
authors.lastname: Staats
authors.affiliation: Center for Sleep Medicine, Mayo Clinic, Rochester, MN.
authors.forename: Erik K
authors.initials: EK
authors.lastname: St Louis
mesh_terms: D000368:Aged; D006801:Humans; D008297:Male; D009666:Nose; D017286:Polysomnography; D011175:Positive-Pressure Respiration / Q000009:adverse effects* / Q000295:instrumentation; D020181:Sleep Apnea, Obstructive / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy
keywords: complex sleep apnea syndrome; nasal expiratory positive airway; obstructive sleep apnea