title: [Optimization of formulas of Quban gel by uniform design].
abstract: OBJECTIVE
  To optimize formulas of Quban gel.
  
  
  METHODS
  The U6 (6(2) x 3) uniform design was adopted to optimize gel formulas, with rheological parameters, such as viscosity and yield value in room temperature, viscosity and yield value in average temperature of skin, thixlotropy.
  
  
  RESULTS
  The optimum proportion of matrix was made of 1.0 g carbomer 940, 5 mL glycerin and pH value 5-6.
  
  
  CONCLUSIONS
  The regression model for gel matrix quality and gel rheological parameters was established to directly reflect the impacting effect of various factors, and provide certain preference basis for the screening of gel matrix formulas. Quban gel prepared by the method was evenly distributed, moderately viscous and highly thixotropic
authors.forename: Hong-Ye
authors.initials: HY
authors.lastname: Guo
authors.forename: Xiao-Ping
authors.initials: XP
authors.lastname: Yan
authors.forename: Bo-Wen
authors.initials: BW
authors.lastname: Yi
authors.forename: Rui
authors.initials: R
authors.lastname: Zheng
authors.forename: Ying
authors.initials: Y
authors.lastname: Kuang
mesh_terms: D002626:Chemistry, Pharmaceutical / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D005782:Gels; D011786:Quality Control; D012044:Regression Analysis; D014783:Viscosity
chemical_list: D004365:Drugs, Chinese Herbal; D005782:Gels