title: Impaired Fasting Glucose in Omani Adults with no Family History of Type 2 Diabetes.
abstract: OBJECTIVE
  The aim of this study was to estimate the prevalence of impaired fasting glucose (IFG) among Omani adults with no family history (FH) of diabetes and to investigate the factors behind the risk of developing type 2 diabetes (T2D), while excluding a FH of diabetes.
  
  
  METHODS
  A total of 1,182 Omani adults, aged ≥40 years, visited the Family Medicine & Community Health Clinic at Sultan Qaboos University Hospital, Oman, on days other than the Diabetes Clinic days, from July 2010 to July 2011. The subjects were interviewed and asked if they had T2D or a FH of T2D.
  
  
  RESULTS
  Only 191 (16%) reported no personal history of T2D or FH of the disease. Of these, anthropometric and biochemical data was complete in 159 subjects. Of these a total of 42 (26%) had IFG according to the American Diabetes Association criteria. Body mass index, fasting insulin, haemoglobin A1C and blood pressure (BP), were significantly higher among individuals with IFG (P <0.01, P <0.05, P <0.01 and P <0.01, respectively). In addition, fasting insulin, BP and serum lipid profile were correlated with obesity indices (P <0.05). Obesity indices were strongly associated with the risk of IFG among Omanis, with waist circumference being the strongest predictor.
  
  
  CONCLUSIONS
  Despite claiming no FH of diabetes, a large number of Omani adults in this study had a high risk of developing diabetes. This is possibly due to environmental factors and endogamy. The high prevalence of obesity combined with genetically susceptible individuals is a warning that diabetes could be a future epidemic in Oman.
authors.affiliation: Departments of Biochemistry, College of Medicine & Health Sciences, Sultan Qaboos University;
authors.forename: Sawsan
authors.initials: S
authors.lastname: Al-Sinani
authors.affiliation: Family Medicine & Public Health, College of Medicine & Health Sciences, Sultan Qaboos University;
authors.forename: Mohammed
authors.initials: M
authors.lastname: Al-Shafaee
authors.affiliation: Departments of Medicine, Sultan Qaboos University Hospital, Muscat, Oman.
authors.forename: Ali
authors.initials: A
authors.lastname: Al-Mamari
authors.affiliation: Medicine, College of Medicine & Health Sciences, Sultan Qaboos University;
authors.forename: Nicolas
authors.initials: N
authors.lastname: Woodhouse
authors.affiliation: Departments of Medicine, Sultan Qaboos University Hospital, Muscat, Oman.
authors.forename: Omayma
authors.initials: O
authors.lastname: El-Shafie
authors.affiliation: Physiology, College of Medicine & Health Sciences, Sultan Qaboos University;
authors.forename: Mohammed O
authors.initials: MO
authors.lastname: Hassan
authors.affiliation: Genetics, College of Medicine & Health Sciences, Sultan Qaboos University;
authors.forename: Said
authors.initials: S
authors.lastname: Al-Yahyaee
authors.affiliation: Physiology, College of Medicine & Health Sciences, Sultan Qaboos University;
authors.forename: Sulayma
authors.initials: S
authors.lastname: Albarwani
authors.affiliation: Clinical Physiology, Sultan Qaboos University Hospital, Muscat, Oman.
authors.forename: Deepali
authors.initials: D
authors.lastname: Jaju
authors.affiliation: Medicine, College of Medicine & Health Sciences, Sultan Qaboos University;
authors.forename: Khamis
authors.initials: K
authors.lastname: Al-Hashmi
authors.affiliation: Clinical Physiology, Sultan Qaboos University Hospital, Muscat, Oman.
authors.forename: Mohammed
authors.initials: M
authors.lastname: Al-Abri
authors.affiliation: Family Medicine & Public Health, College of Medicine & Health Sciences, Sultan Qaboos University;
authors.forename: Syed
authors.initials: S
authors.lastname: Rizvi
authors.affiliation: Departments of Biochemistry, College of Medicine & Health Sciences, Sultan Qaboos University;
authors.forename: Riad
authors.initials: R
authors.lastname: Bayoumi
keywords: Diabetes Mellitus, Type 2; Obesity; Oman; Prediabetic State; Prevalence