title: Targeting epigenetics to speed up repair.
abstract: In this issue of Cell Stem Cell, Palii et al. reveal that TAL1 is a master regulator of adhesion and migration networks in human endothelial progenitors and that ex vivo treatment with the histone deacetylase inhibitor TSA enables their faster vascularization after ischemic injury.
authors.affiliation: INSERM UMR967 CEA/DSV/iRCM, 92265 Fontenay-aux-Roses, France. Electronic address: eric.soler@cea.fr.
authors.forename: Eric
authors.initials: E
authors.lastname: Soler
authors.affiliation: Department of Cell Biology, Erasmus Medical Center, Rotterdam, The Netherlands. Electronic address: f.grosveld@erasmusmc.nl.
authors.forename: Frank
authors.initials: F
authors.lastname: Grosveld
mesh_terms: D051792:Basic Helix-Loop-Helix Proteins / Q000378:metabolism*; D066026:Endothelial Progenitor Cells / Q000187:drug effects* / Q000378:metabolism*; D006801:Humans; D006877:Hydroxamic Acids / Q000494:pharmacology*; D011518:Proto-Oncogene Proteins / Q000378:metabolism*; D000073942:T-Cell Acute Lymphocytic Leukemia Protein 1
chemical_list: D051792:Basic Helix-Loop-Helix Proteins; D006877:Hydroxamic Acids; D011518:Proto-Oncogene Proteins; D000073942:T-Cell Acute Lymphocytic Leukemia Protein 1; C067143:TAL1 protein, human; C012589:trichostatin A