title: Endoscopic transnasal transsphenoidal approach for craniopharyngioma: report of 6 cases.
abstract: We conducted a retrospective study to evaluate outcomes in patients with a craniopharyngioma who were managed via a transnasal transsphenoidal approach. Craniopharyngiomas exhibit histologically benign but "clinically malignant" features. Our study group was made up of 5 patients who underwent a total of 6 operations. The study population included 1 female and 5 males, aged 14 to 50 years (mean: 29.2). The overall rate of near-total tumor removal was 67%, but all patients eventually experienced a recurrence. Revision surgery to correct any severe postoperative complications was not required in any case. We found that the endoscopic transnasal transsphenoidal approach could be a safe and less invasive surgical option for the removal of craniopharyngiomas, although we were unable to remove all tumor or prevent recurrences.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, St. Vincent's Hospital, Suwon City, Korea.
authors.forename: Chan-Soon
authors.initials: CS
authors.lastname: Park
authors.forename: Byung-Guk
authors.initials: BG
authors.lastname: Kim
authors.forename: Ji-Hyeon
authors.initials: JH
authors.lastname: Shin
authors.forename: Jin-Hee
authors.initials: JH
authors.lastname: Cho
mesh_terms: D000293:Adolescent; D000328:Adult; D003397:Craniopharyngioma / Q000473:pathology / Q000601:surgery*; D004724:Endoscopy / Q000379:methods*; D005260:Female; D005682:Gadolinium; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D009666:Nose; D010911:Pituitary Neoplasms / Q000473:pathology / Q000601:surgery*; D011868:Radioisotopes; D012086:Reoperation; D012189:Retrospective Studies; D013101:Sphenoid Sinus; D016896:Treatment Outcome
chemical_list: D011868:Radioisotopes; D005682:Gadolinium