title: [Treatment of severe asthma: expert opinion].
abstract: Severe asthmatics account 10% of the all asthmatic population. Those asthmatics whose disease is inadequately controlled account for up to half of the cost for asthma, because they have more emergency room visits, more hospital admission and greater absenteeism from work. New therapeutic options were tried in those patients whose asthma was uncontrolled with standart high dose inhaled corticosteroid and long acting beta-2 agonsit combination therapy. In this paper taking into account the conditions of our country, current literature was reviewed and treatment options was discussed and graded recommendations are made for daily clinical practice in patients with severe treatment-refractory asthma.
authors.affiliation: Department of Chest Diseases, Faculty of Medicine, Gazi University, Ankara, Turkey. halukturktas@gmail.com.
authors.forename: Haluk
authors.initials: H
authors.lastname: Türktaş
authors.forename: Sevim
authors.initials: S
authors.lastname: Bavbek
authors.forename: Gülfem
authors.initials: G
authors.lastname: Celik
authors.forename: Tunçalp
authors.initials: T
authors.lastname: Demir
authors.forename: Bilun
authors.initials: B
authors.lastname: Gemicioğlu
authors.forename: Hakan
authors.initials: H
authors.lastname: Günen
authors.forename: Esen
authors.initials: E
authors.lastname: Kiyan
authors.forename: Dilşad
authors.initials: D
authors.lastname: Mungan
authors.forename: Ipek Kıvılcım
authors.initials: IK
authors.lastname: Oğuzülgen
authors.forename: Mehmet
authors.initials: M
authors.lastname: Polatli
authors.forename: Sevgi
authors.initials: S
authors.lastname: Saryal
authors.forename: Abdullah
authors.initials: A
authors.lastname: Sayiner
authors.forename: Elif
authors.initials: E
authors.lastname: Sen
authors.forename: Nurhayat
authors.initials: N
authors.lastname: Yildirim
authors.forename: Füsun
authors.initials: F
authors.lastname: Yildiz
authors.forename: Arzu
authors.initials: A
authors.lastname: Yorgancioğlu
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use*; D058666:Adrenergic beta-2 Receptor Agonists / Q000627:therapeutic use*; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy* / Q000503:physiopathology; D004359:Drug Therapy, Combination; D004636:Emergency Service, Hospital; D006760:Hospitalization; D006801:Humans; D012720:Severity of Illness Index
chemical_list: D000305:Adrenal Cortex Hormones; D058666:Adrenergic beta-2 Receptor Agonists; D018927:Anti-Asthmatic Agents