title: Unusual presentation of xanthogranuloma on the eyelid of an adult.
abstract: A 46-year-old man presented with an unusual papillary eyelid lesion in which histopathological study revealed a cutaneous xanthogranuloma. The clinical appearance was distinctively different from juvenile xanthogranuloma. There was no evidence of an infiltrative and orbital process consistent with adult orbital xanthogranulomatous disease. The histopathologic examination of the lesion revealed well-differentiated histiocytes with foamy cytoplasm. Immunohistochemistry stains were positive for CD163 and Factor XIIIa and negative for CD34, CD1A, CD117, and S100. The final histopathologic diagnosis was cutaneous xanthogranuloma.
authors.affiliation: Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, U.S.A.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Chiang
authors.forename: Gary
authors.initials: G
authors.lastname: Lissner
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Bryar
mesh_terms: D015703:Antigens, CD / Q000378:metabolism; D015415:Biomarkers / Q000378:metabolism; D005141:Eyelid Diseases / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D006099:Granuloma / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D013508:Ophthalmologic Surgical Procedures; D014973:Xanthomatosis / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery
chemical_list: D015703:Antigens, CD; D015415:Biomarkers