title: Relationship between the surface energy and the histologic results of different titanium surfaces.
abstract: The aim of this study was to evaluate, through in vitro and in vivo studies, the existence of a relationship between surface energy, for wettability, and the clinical behavior of dental implants with different surfaces, one with a surface treated by sandblasting with titanium oxide microparticles followed by acid-etching treatment (experimental group) and another with a machined surface (control group). For the in vitro tests, a total of 30 titanium disks (15 disks for each group) were evaluated by scanning electron microscopy and dispersive energy spectroscopy and for surface roughness and wettability. For the in vivo tests, a total of 24 implants (12 implants for each group) were inserted in the tibiae of 6 rabbits and were removed after 30 and 60 days for histologic analysis. The results showed that the implants with the experimental surface presented a low wettability, and it also resulted in highly stimulated new bone formation in vivo, when compared with the control group dental implant. As for the bone formation, differences between the different surfaces seemed evident, both in quantity and in quality, as implants from the experimental group showed a higher new bone deposition than that from the control group. Thus, in vitro and in vivo tests demonstrated an excellent biologic response of the surfaces treated by sandblasting with microparticles of titanium oxide followed by acid etching.
authors.affiliation: From the *Catholic University of Uruguay, Montevideo, Uruguay; Departments of †Pharmacy and ‡Medical, Oral and Biotechnological Science, University "G. d'Annunzio," Chieti, Italy; §Department of Medical Science, Faculty of Medicine, University of Eastern Piedmont, Novara, Italy; and ∥Oral Surgery Unit, Regina Margherita Pediatric Hospital, Turin, Italy.
authors.forename: Sergio Alexandre
authors.initials: SA
authors.lastname: Gehrke
authors.forename: Vincenzo Luca
authors.initials: VL
authors.lastname: Zizzari
authors.forename: Flavia
authors.initials: F
authors.lastname: Iaculli
authors.forename: Carmen
authors.initials: C
authors.lastname: Mortellaro
authors.forename: Stefano
authors.initials: S
authors.lastname: Tetè
authors.forename: Adriano
authors.initials: A
authors.lastname: Piattelli
mesh_terms: D000818:Animals; D002113:Calcification, Physiologic / Q000502:physiology; D045662:Dental Etching / Q000379:methods; D015921:Dental Implants; D003775:Dental Polishing; D020007:Implants, Experimental; D053844:Lasers, Solid-State; D008855:Microscopy, Electron, Scanning; D023421:Models, Animal; D016348:Osseointegration / Q000502:physiology; D011817:Rabbits; D013499:Surface Properties; D013977:Tibia / Q000502:physiology / Q000601:surgery; D014025:Titanium; D017155:Wettability
chemical_list: D015921:Dental Implants; C009495:titanium dioxide; D014025:Titanium