title: Comparison of autofluorescence and optical coherence tomography findings in acute and chronic central serous chorioretinopathy.
abstract: OBJECTIVE
  To discuss and compare the fundus autofluorescence (FAF) and optical coherence tomography (OCT) in acute or chronic central serous chorioretinopathy (CSCR).
  
  
  METHODS
  Medical records of 100 cases of CSCR were reviewed. Acute and chronic cases were evaluated according to the duration of decreased visual acuity, serous retinal detachment (RD) and focal leakage on fluorescein angiography (FA). Chi-square test was used for statistical analysis.
  
  
  RESULTS
  Forty cases had acute and 60 cases had chronic CSCR. FAF showed focal hypo-autofluorescence in 34 (85%) and iso-autofluorescence in 6 (15%) of acute cases and hypo-autofluorescence in 51 (85%), hyper-autofluorescence in 6 (10%) and iso-autofluorescence in 3 (5%) of chronic cases. OCT showed serous RD with distinct borders correlated with FAF findings (hypo-autofluorescence) in all acute CSCR cases. In chronic CSCR group, OCT showed serous RD with indistinct borders correlated with FAF findings. The differences between the OCT and FAF findings of the two groups were significant (P=0.000).
  
  
  CONCLUSIONS
  OCT and FAF findings can support the clinical observations in differential diagnosis of acute and chronic CSCR and help clinicians to evaluate retinal pigment epithelium, outer segments of photoreceptors and the components of serous RD.
authors.affiliation: Ulucanlar Eye Research Hospital, Ankara 06240, Turkey.
authors.forename: Mehmet Yasin
authors.initials: MY
authors.lastname: Teke
authors.affiliation: Ulucanlar Eye Research Hospital, Ankara 06240, Turkey.
authors.forename: Ufuk
authors.initials: U
authors.lastname: Elgin
authors.affiliation: Ulucanlar Eye Research Hospital, Ankara 06240, Turkey.
authors.forename: Pinar
authors.initials: P
authors.lastname: Nalcacioglu-Yuksekkaya
authors.affiliation: Ulucanlar Eye Research Hospital, Ankara 06240, Turkey.
authors.forename: Emine
authors.initials: E
authors.lastname: Sen
authors.affiliation: Ulucanlar Eye Research Hospital, Ankara 06240, Turkey.
authors.forename: Pinar
authors.initials: P
authors.lastname: Ozdal
authors.affiliation: Ulucanlar Eye Research Hospital, Ankara 06240, Turkey.
authors.forename: Faruk
authors.initials: F
authors.lastname: Ozturk
keywords: central serous chorioretinopathy; fluorescein angiography; fundus autofluorescence; optical coherence tomography