title: [Research on Chinese medicine pairs (IV)--Their compatibility effects].
abstract: Chinese medicine pairs (CMP) are specific compatibility with traditional Chinese medicine (TCM) theory as principle, which was formed on basis of effect and treatment theory of TCM. The compatibility of CMP can enhance the effect, or reduce the toxicity. So, compatibility effects of CMP were studied from different pharmacology levels including animals, tissues and organs, cell and molecular levels, their synergy and compatibility attenuation were also evaluated with monomer component-component (group) compatibility-single herb-CMP-formulae as the main line, and the action mechanisms were investigated, all of which can provide scientific basis for the clinical applications of CMP and creation of TCM new drugs.
authors.forename: Wei-Xia
authors.initials: WX
authors.lastname: Li
authors.forename: Yu-Ping
authors.initials: YP
authors.lastname: Tang
authors.forename: Xu-Qin
authors.initials: XQ
authors.lastname: Shi
authors.forename: Jian-Ming
authors.initials: JM
authors.lastname: Guo
authors.forename: Pei
authors.initials: P
authors.lastname: Liu
authors.forename: Jin-Ao
authors.initials: JA
authors.lastname: Duan
mesh_terms: D000818:Animals; D004347:Drug Interactions; D004357:Drug Synergism; D064420:Drug-Related Side Effects and Adverse Reactions / Q000517:prevention & control; D006801:Humans; D008516:Medicine, Chinese Traditional / Q000009:adverse effects / Q000379:methods*