title: Spatio-temporal dynamics of dengue 2009 outbreak in Córdoba City, Argentina.
abstract: During 2009 the biggest dengue epidemic to date occurred in Argentina, affecting almost half the country. We studied the spatio-temporal dynamics of the outbreak in the second most populated city of the country, Córdoba city. Confirmed cases and the results of an Aedes aegypti monitoring during the outbreak were geolocated. The imported cases began in January, and the autochthonous in March. Thirty-three percent of the 130 confirmed cases were imported, and occurred mainly at the center of the city. The autochthonous cases were more frequent in the outskirts, specially in the NE and SE. Aedes aegypti infestation showed no difference between neighborhoods with or without autochthonous cases, neither between neighborhoods with autochthonous vs. imported cases. The neighborhoods with imported cases presented higher population densities. The majority of autochthonous cases occurred at ages between 25 and 44 years old. Cases formed a spatio-temporal cluster of up to 20 days and 12km. According to a mathematical model that estimates the required number of days needed for transmission according to daily temperature, the number of cases begun to fall when more than 15.5 days were needed. This may be a coarse estimation of mean mosquito survival in the area, provided that the study area is close to the global distribution limit of the vector, and that cases prevalence was very low.
authors.affiliation: Instituto de Investigaciones Biológicas y Tecnológicas (IIBYT) CONICET and Universidad Nacional de Córdoba. Centro de Investigaciones Entomológicas de Córdoba (CIEC), Facultad de Ciencias Exactas, Físicas y Naturales. Universidad Nacional de Córdoba, Av. Vélez Sarsfield 1611 (X5016GCA), Ciudad Universitaria, Córdoba, Argentina. Electronic address: eelizabet@gmail.com.
authors.forename: E L
authors.initials: EL
authors.lastname: Estallo
authors.affiliation: Ecología de Enfermedades Transmitidas por Vectores (EETV), Instituto de Investigaciones e Ingeniería Ambiental (3iA), Universidad Nacional de San Martín. Campus Miguelete, 25 de Mayo y Francia (1650), San Martín, Buenos Aires, Argentina.
authors.forename: A E
authors.initials: AE
authors.lastname: Carbajo
authors.affiliation: Laboratorio de Investigaciones en Ecología y Sistemática Animal (LIESA). Universidad Nacional de la Patagonia San Juan Bosco, FCN-Sede Esquel, Sarmiento 849 (9200), Esquel, Chubut, Argentina.
authors.forename: M G
authors.initials: MG
authors.lastname: Grech
authors.affiliation: Dirección de Epidemiología, Ministerio de Salud de la Provincia de Córdoba, Rosario de Santa Fe 473 (5000), Córdoba, Argentina.
authors.forename: M
authors.initials: M
authors.lastname: Frías-Céspedes
authors.affiliation: Dirección de Epidemiología, Ministerio de Salud de la Provincia de Córdoba, Rosario de Santa Fe 473 (5000), Córdoba, Argentina.
authors.forename: L
authors.initials: L
authors.lastname: López
authors.affiliation: Instituto de Altos Estudios Espaciales Mario Gulich, Comisión Nacional de Actividades Espaciales (CONAE), Centro Espacial Teófilo Tabanera, Ruta C45 km 8, Falda del cañete, (5187), Córdoba, Argentina.
authors.forename: M A
authors.initials: MA
authors.lastname: Lanfri
authors.affiliation: Instituto de Investigaciones Biológicas y Tecnológicas (IIBYT) CONICET and Universidad Nacional de Córdoba. Centro de Investigaciones Entomológicas de Córdoba (CIEC), Facultad de Ciencias Exactas, Físicas y Naturales. Universidad Nacional de Córdoba, Av. Vélez Sarsfield 1611 (X5016GCA), Ciudad Universitaria, Córdoba, Argentina.
authors.forename: F F
authors.initials: FF
authors.lastname: Ludueña-Almeida
authors.affiliation: Instituto de Investigaciones Biológicas y Tecnológicas (IIBYT) CONICET and Universidad Nacional de Córdoba. Centro de Investigaciones Entomológicas de Córdoba (CIEC), Facultad de Ciencias Exactas, Físicas y Naturales. Universidad Nacional de Córdoba, Av. Vélez Sarsfield 1611 (X5016GCA), Ciudad Universitaria, Córdoba, Argentina.
authors.forename: W R
authors.initials: WR
authors.lastname: Almirón
mesh_terms: D000330:Aedes / Q000502:physiology; D000818:Animals; D001118:Argentina; D003715:Dengue / Q000453:epidemiology*; D004196:Disease Outbreaks; D006801:Humans; D007303:Insect Vectors / Q000502:physiology; D013997:Time Factors; D014505:Urban Population
keywords: Aedes aegypti; Argentina; Córdoba; Dengue outbreak; Geographic information system (GIS)