title: Evidence of altered fertility in female roach (Rutilus rutilus) from the River Seine (France).
abstract: A large variety of anthropogenic chemicals present in the aquatic environment have been shown to be able to alter the endocrine system of exposed organisms, potentially impacting their reproductive function. The aim of this study was to assess the effects of environmental pollution on the reproductive system of wild female roach (Rutilus rutilus) from the Seine River (Normandy, France). A suite of biomarkers of endocrine disruption including gonado-somatic index, plasmatic vitellogenin, gonadal aromatase activity and histological parameters (oocyte diameter and gonad maturation) were studied. Female fish from the polluted sites showed a number of reproductive alterations, including inhibited gonad maturation, reduced oocyte growth, reduced levels of plasmatic vitellogenin and 3-fold lower gonadal aromatase activity than females collected in the reference site. Overall, these results highlight the presence of endocrine disruption in female roach from the Seine River.
authors.affiliation: Laboratory of Ecotoxicology, ULH Normandie Université, SFR SACLE 4116, BP 540, 76058 Le Havre, France. Electronic address: mariegerbron@hotmail.fr.
authors.forename: M
authors.initials: M
authors.lastname: Gerbron
authors.affiliation: Laboratory of Ecotoxicology, ULH Normandie Université, SFR SACLE 4116, BP 540, 76058 Le Havre, France; Akvaplan-Niva, High North Research Centre, 9296 Tromsø, Norway.
authors.forename: P
authors.initials: P
authors.lastname: Geraudie
authors.affiliation: Environmental Chemistry Department, IDAEA-CSIC, C/Jordi Girona, 18, 08034 Barcelona, Spain.
authors.forename: D
authors.initials: D
authors.lastname: Fernandes
authors.affiliation: Department of Biological Sciences, University of Hull, Cottingham Road, Hull HU6 7RX, United Kingdom.
authors.forename: J M
authors.initials: JM
authors.lastname: Rotchell
authors.affiliation: Environmental Chemistry Department, IDAEA-CSIC, C/Jordi Girona, 18, 08034 Barcelona, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Porte
authors.affiliation: Laboratory of Ecotoxicology, ULH Normandie Université, SFR SACLE 4116, BP 540, 76058 Le Havre, France.
authors.forename: C
authors.initials: C
authors.lastname: Minier
mesh_terms: D000818:Animals; D003530:Cyprinidae / Q000378:metabolism / Q000502:physiology*; D052244:Endocrine Disruptors / Q000506:poisoning*; D004703:Endocrine System / Q000187:drug effects; D005260:Female; D005298:Fertility / Q000187:drug effects; D005602:France; D007247:Infertility, Female / Q000139:chemically induced / Q000662:veterinary; D008297:Male; D012098:Reproduction / Q000187:drug effects; D045483:Rivers; D014819:Vitellogenins / Q000378:metabolism; D014874:Water Pollutants, Chemical / Q000506:poisoning*
chemical_list: D052244:Endocrine Disruptors; D014819:Vitellogenins; D014874:Water Pollutants, Chemical
keywords: Aromatase activity; Endocrine disruption; Female roach; Vitellogenin