title: Treatment of severe hypertriglyceridemia with continuous insulin infusion.
abstract: Severe hypertriglyceridemia (SH) represents a therapeutic emergency because of the possibility of developing cardiovascular events and hyperlipemic acute pancreatitis (PA). Most patients with SH suffer primary or genetic abnormality in lipid metabolism in combination with a precipitating factor such as uncontrolled diabetes mellitus, alcoholism, and drug intake. The standard treatment of hypertriglyceridemia (HTG) with omega 3 fatty acids and fibrates, along with dietary changes, has no effect on an emergency situation. There are no clinical guidelines to SH, but therapy with insulin, heparin, a combination of both, plasmapheresis, or octreotide have been tested succesfully. We report the case of a 10-year-old girl with clinical acute pancreatitis and diabetic ketoacidosis debut, along with incidental finding of an SH, who had a good outcome after treatment with insulin intravenous infusion.
authors.affiliation: Pediatric Intensive Care Unit, Hospital Universitario Materno-Infantil, 35016 Las Palmas de Gran Canaria, Spain.
authors.forename: Yesica
authors.initials: Y
authors.lastname: Rodríguez Santana
authors.affiliation: Pediatric Intensive Care Unit, Hospital Universitario Materno-Infantil, 35016 Las Palmas de Gran Canaria, Spain.
authors.forename: Andrea
authors.initials: A
authors.lastname: Nimo Román
authors.affiliation: Pediatric Intensive Care Unit, Hospital Universitario Materno-Infantil, 35016 Las Palmas de Gran Canaria, Spain.
authors.forename: Iker
authors.initials: I
authors.lastname: García Sáez
authors.affiliation: Pediatric Intensive Care Unit, Hospital Universitario Materno-Infantil, 35016 Las Palmas de Gran Canaria, Spain.
authors.forename: José Manuel
authors.initials: JM
authors.lastname: López Alvarez
authors.affiliation: Pediatric Intensive Care Unit, Hospital Universitario Materno-Infantil, 35016 Las Palmas de Gran Canaria, Spain.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Consuegra Llapur
authors.affiliation: Pediatric Intensive Care Unit, Hospital Universitario Materno-Infantil, 35016 Las Palmas de Gran Canaria, Spain.
authors.forename: Rafael
authors.initials: R
authors.lastname: González Jorge