title: Benzodiazepines consumption: does dependence vary with age?
abstract: We have compared two groups of chronic benzodiazepines (or zolpidem/zopiclone) users: "Seniors," aged 65 years or more, and "Adults," aged less than 65 years. The study took place in the Pays de Loire region. The questionnaire assesses dependence based on items from the DSM-IV. The analysis was based on 176 Senior questionnaires and 212 Adult questionnaires. Whereas Senior patients take benzodiazepines routinely with little negative consequences, Adults suffer from underlying psychological trouble, mention a higher consumption than planned, which causes negative consequences. 35.2% of Seniors are dependent on benzodiazepines versus 49.8% of Adults.
authors.affiliation: 1Department of Clinical Pharmacology, University Hospital of Nantes, Nantes, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Gérardin
authors.forename: Caroline
authors.initials: C
authors.lastname: Victorri-Vigneau
authors.forename: Marylène
authors.initials: M
authors.lastname: Guerlais
authors.forename: Morgane
authors.initials: M
authors.lastname: Guillou-Landreat
authors.forename: Marie
authors.initials: M
authors.lastname: Grall-Bronnec
authors.forename: Pascale
authors.initials: P
authors.lastname: Jolliet
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001569:Benzodiazepines / Q000008:administration & dosage*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019966:Substance-Related Disorders / Q000175:diagnosis*; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D001569:Benzodiazepines
keywords: adults; age; benzodiazepines; pharmacodependence; seniors