title: Breast carcinoma in a prepubertal girl.
abstract: Breast carcinoma is a very rare disease in children. We present a rare case of breast cancer in an 11-year-old prepubertal girl. Clinically, it was a case of locally advanced breast cancer (T4bN1M0). The core biopsy report showed adenocarcinoma of the not otherwise specified (NOS) variety (oestrogen receptor-negative, progesterone receptor-negative and human epidermal growth factor receptor 2-negative). Diagnosis was late in this case due to lack of suspicion. A modified radical mastectomy was considered to be adequate treatment. Histologically, it was adenocarcinoma NOS, which is rare in young girls (the secretory type being more common). Incidence, differential diagnoses, investigation and management of breast carcinoma in young girls are discussed. The purpose of reporting this case is to highlight that prevention and early detection of breast carcinoma in children is very important.
authors.affiliation: Department of General Surgery, RGKAR Hospital, Kolkata, West Bengal, India.
authors.forename: Syed Tausif
authors.initials: ST
authors.lastname: Ahmed
authors.forename: Sudipto Kumar
authors.initials: SK
authors.lastname: Singh
authors.forename: Tanmoy
authors.initials: T
authors.lastname: Mukherjee
authors.forename: Manju
authors.initials: M
authors.lastname: Banerjee
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D044963:Biopsy, Fine-Needle; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000473:pathology* / Q000601:surgery; D002648:Child; D057210:Delayed Diagnosis; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D015411:Mastectomy, Modified Radical; D016217:Ultrasonography, Mammary