title: [Genomic medicine and infectious diseases].
abstract: Relentless progress in our knowledge of the nature and functional consequences of human genetic variation allows for a better understanding of the protracted battle between pathogens and their human hosts. Multiple polymorphisms have been identified that impact our response to infections or to anti-infective drugs, and some of them are already used in the clinic. However, to make personalized medicine a reality in infectious diseases, a sustained effort is needed not only in research but also in genomic education.
authors.affiliation: Faculté des Sciences de la Vie, EPFL, Service des Maladies Infectieuses, CHUV, Institut Suisse de Bioinformatique, Lausanne.
authors.forename: Jacques
authors.initials: J
authors.lastname: Fellay
mesh_terms: D003141:Communicable Diseases / Q000235:genetics*; D003299:Cooperative Behavior; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D036281:Genetic Research; D005820:Genetic Testing; D015894:Genome, Human / Q000235:genetics*; D006801:Humans; D033183:Interdisciplinary Communication; D010597:Pharmacogenetics; D011110:Polymorphism, Genetic / Q000235:genetics; D057285:Precision Medicine; D013557:Switzerland
keywords: Infekionskrankheiten; Koevolution; Pharmakogenetik; coevolution; coévolution; génomique humaine; human genome; infectious diseases; maladies infectieuses; menschliches Genom; médecine personnalisée; personalised medicine; personalisierte Medizin; pharmacogenetics; pharmacogénétique