title: [Tako-tsubo syndrome: analysis of a series of 60 cases].
abstract: OBJECTIVE
  The Tako-tsubo syndrome (TS) is a reversible acute cardiomyopathy simulating an infarction. We analyzed 60 patients admitted with TS in our center.
  
  
  METHODS
  A percentage of 73.3 were women (mean age: 70.6 ± 11.8 years); 83.3% had some cardiovascular risk factor, 25% had an anxiety-depressive disorder and in 58.3% a precipitating factor was identified, emotional stress being the most frequent. A percentage of 15.3 showed complete left bundle branch block (LBBB). In 23.3% of patients, contractile abnormalities respected the apex (mid ventricular or diaphragmatic types).
  
  
  RESULTS
  The anterior descending artery showed no significant lesions in 35% of patients and in 68.3% it had a diaphragmatic segment. Forty percent of patients developed heart failure (HF) and 18.3% cardiogenic shock (CS). The overall in-hospital mortality was 3.3%, while it was 8.3% among those patients who developed HF. The incidence of CS was higher among patients with LBBB (44.4 vs. 13.7%, P=.05) and males (43.8 vs. 9.1%, P=.005).
  
  
  CONCLUSIONS
  Although in-hospital mortality in patients admitted due to TS is low, a significant percentage of these patients develop HF with a high mortality in this subgroup. Males and patients with LBBB had higher in-hospital morbidity.
authors.affiliation: Sección de Hemodinámica y Cardiología Intervencionista, Servicio de Cardiología, Hospital Universitario Infanta Cristina, Badajoz, España. Electronic address: juanmanogales@yahoo.es.
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: Nogales-Asensio
authors.affiliation: Sección de Hemodinámica y Cardiología Intervencionista, Servicio de Cardiología, Hospital Universitario Infanta Cristina, Badajoz, España.
authors.forename: Maria Reyes
authors.initials: MR
authors.lastname: González-Fernández
authors.affiliation: Sección de Hemodinámica y Cardiología Intervencionista, Servicio de Cardiología, Hospital Universitario Infanta Cristina, Badajoz, España.
authors.forename: Jose Ramón
authors.initials: JR
authors.lastname: López-Mínguez
authors.affiliation: Sección de Hemodinámica y Cardiología Intervencionista, Servicio de Cardiología, Hospital Universitario Infanta Cristina, Badajoz, España.
authors.forename: Antonio
authors.initials: A
authors.lastname: Merchán-Herrera
authors.affiliation: Sección de Hemodinámica y Cardiología Intervencionista, Servicio de Cardiología, Hospital Universitario Infanta Cristina, Badajoz, España.
authors.forename: Ginés
authors.initials: G
authors.lastname: Martínez-Cáceres
authors.affiliation: Sección de Hemodinámica y Cardiología Intervencionista, Servicio de Cardiología, Hospital Universitario Infanta Cristina, Badajoz, España.
authors.forename: Carlos
authors.initials: C
authors.lastname: Aranda-López
mesh_terms: D054058:Acute Coronary Syndrome / Q000209:etiology; D000328:Adult; D017677:Age Distribution; D000368:Aged; D001008:Anxiety Disorders / Q000150:complications; D002037:Bundle-Branch Block / Q000453:epidemiology; D003866:Depressive Disorder / Q000150:complications; D005260:Female; D006333:Heart Failure / Q000453:epidemiology / Q000209:etiology; D017052:Hospital Mortality; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D012770:Shock, Cardiogenic / Q000209:etiology; D013030:Spain / Q000453:epidemiology; D013315:Stress, Psychological / Q000150:complications; D054549:Takotsubo Cardiomyopathy / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*
keywords: Discinesia apical transitoria; Heart failure; Insuficiencia cardiaca; Síndrome de Tako-tsubo; Tako-tsubo syndrome; Transient apical ballooning syndrome