title: Matrix-assisted laser desorption/ionization imaging mass spectrometry: new technology for vascular pathology.
abstract: The use of matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) for the assessment of vascular pathology is attracting attention as a new valuable tool for diagnosing disease and finding new markers. MALDI-IMS is a molecular imaging technique whereby the simultaneous measurement of multiple samples directly from clinical tissue sections is possible. The versatility of MALDI-IMS has opened a new frontier in vascular pathology. In this review, we describe the principle and applications of MALDI-IMS.
authors.affiliation: Department of Applied Biological Chemistry, Graduate School of Agriculture, Kinki University, Nara, Japan.
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Zaima
authors.forename: Naoko
authors.initials: N
authors.lastname: Goto-Inoue
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Moriyama
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D006801:Humans; D050356:Lipid Metabolism; D057054:Molecular Imaging / Q000379:methods*; D011237:Predictive Value of Tests; D011379:Prognosis; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D014652:Vascular Diseases / Q000378:metabolism* / Q000473:pathology
chemical_list: D015415:Biomarkers