title: Palladium-catalyzed C-H homocoupling of furans and thiophenes using oxygen as the oxidant.
abstract: A general and efficient palladium-catalyzed intermolecular direct C-H homocoupling of furans and thiophenes has been developed. The reaction is characterized by using molecular oxygen as the sole oxidant and complete C5-position regioselectivity. Both C2- and C3-substituted furans or thiophenes are appropriate substrates. The approach provides a straightforward, facile, and economical route to bifurans and bithiophenes under mild reaction conditions.
authors.affiliation: Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry & Materials Science, Northwest University , Xi'an 710069, P. R. China.
authors.forename: Na-Na
authors.initials: NN
authors.lastname: Li
authors.forename: Yan-Lei
authors.initials: YL
authors.lastname: Zhang
authors.forename: Shuai
authors.initials: S
authors.lastname: Mao
authors.forename: Ya-Ru
authors.initials: YR
authors.lastname: Gao
authors.forename: Dong-Dong
authors.initials: DD
authors.lastname: Guo
authors.forename: Yong-Qiang
authors.initials: YQ
authors.lastname: Wang
mesh_terms: D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D005663:Furans / Q000138:chemical synthesis / Q000737:chemistry*; D006574:Heterocyclic Compounds, 2-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D016877:Oxidants / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013876:Thiophenes / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D005663:Furans; D006574:Heterocyclic Compounds, 2-Ring; D016877:Oxidants; D013876:Thiophenes; D010165:Palladium; D010100:Oxygen