title: Latest Study on the Relationship between Pathological Process of Inflammatory Injury and the Syndrome of Spleen Deficiency and Fluid Retention in Alzheimer's Disease.
abstract: Inflammation exists throughout the incidence and progression of Alzheimer's disease (AD). Traditional Chinese medicine (TCM) differentiates the pathogenesis of AD as kidney essence deficiency and qi and blood deficiency as well as blood stasis in syndromes, whose action mechanisms are all associated with the intervention in its inflammatory process. Our preliminary studies both in clinic and in vitro have demonstrated that the syndrome of spleen deficiency and fluid retention has also been an important pathogenesis for the incidence and development of AD. Hence, the paper aims to further illustrate the correlation between inflammatory process in AD and the syndrome of spleen deficiency and fluid retention, laying solid foundation for the application of invigorating the spleen and eliminating the dampness in clinic, and enriching the theoretical connotation for AD prevention and treatment in TCM.
authors.affiliation: Basic Medicine College, Nanjing University of Chinese Medicine, Nanjing 210046, China.
authors.forename: Beibei
authors.initials: B
authors.lastname: Yu
authors.affiliation: Basic Medicine College, Nanjing University of Chinese Medicine, Nanjing 210046, China ; Nanjing BenQ Hospital, Nanjing 210011, China.
authors.forename: Chunxiang
authors.initials: C
authors.lastname: Zhou
authors.affiliation: Basic Medicine College, Nanjing University of Chinese Medicine, Nanjing 210046, China.
authors.forename: Jiangyuan
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Basic Medicine College, Nanjing University of Chinese Medicine, Nanjing 210046, China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Ling
authors.affiliation: Basic Medicine College, Nanjing University of Chinese Medicine, Nanjing 210046, China.
authors.forename: Qianfeng
authors.initials: Q
authors.lastname: Hu
authors.affiliation: Basic Medicine College, Nanjing University of Chinese Medicine, Nanjing 210046, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Basic Medicine College, Nanjing University of Chinese Medicine, Nanjing 210046, China.
authors.forename: Kangkang
authors.initials: K
authors.lastname: Bai