title: 25-Hydroxyvitamin D levels are related to hyperinsulinemia in polycystic ovary syndrome.
abstract: OBJECTIVE
  To determine 25-hydroxyvitamin D levels and the relationship between 25-hydroxyvitamin D and metabolic disturbances including insulin resistance in women with PCOS.
  
  
  METHODS
  We compared biochemical, hormonal parameters and 25-hydroxyvitamin D levels of 58 women with PCOS and 38 body mass index matched controls.
  
  
  RESULTS
  There was no difference in 25-hydroxyvitamin D levels of women with PCOS and the control group. Low 25-hydroxyvitamin D levels in women with PCOS were related to higher insulin levels (r = -0.271 and p = 0.042). More than 90% of the subjects had hypovitaminosis D. The negative relationship between 25-hydroxyvitamin D levels and body mass index did not reach statistical significance.
  
  
  CONCLUSIONS
  Low 25-hydroxyvitamin D levels were related to hyperinsulinemia in women with PCOS.
authors.affiliation: Department of Obstetrics and Gynecology and.
authors.forename: Nilgün
authors.initials: N
authors.lastname: Güdücü
authors.forename: Uzay
authors.initials: U
authors.lastname: Görmüş
authors.forename: Salih Serdar
authors.initials: SS
authors.lastname: Kutay
authors.forename: Zehra Neşe
authors.initials: ZN
authors.lastname: Kavak
authors.forename: Ilkkan
authors.initials: I
authors.lastname: Dünder
mesh_terms: D000328:Adult; D015992:Body Mass Index; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006946:Hyperinsulinism / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D007328:Insulin / Q000097:blood*; D007333:Insulin Resistance; D009765:Obesity / Q000097:blood / Q000150:complications / Q000453:epidemiology; D011085:Polycystic Ovary Syndrome / Q000097:blood* / Q000453:epidemiology; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000097:blood / Q000150:complications / Q000453:epidemiology; D055815:Young Adult
chemical_list: D007328:Insulin; D014807:Vitamin D; C104450:25-hydroxyvitamin D
keywords: Insulin resistance; obesity; polycystic ovary syndrome; vitamin D