title: Hemophagocytic lymphohistiocytosis and dengue infection: rare case report.
abstract: We describe a 21-year-old female patient returning from a journey to Cambodia, who developed dengue fever complicated with hemophagocytic lymphohistiocytosis. Hectic fever, rash, leukopenia, thrombocytopenia, hepatocellular dysfunction, a markedly elevated ferritin level, and a bone marrow demonstrating abundant hemophagocytosis were present. The patient recovered within 14 days. To our knowledge, this is only the second reported case of dengue virus-associated hemophagocytosis in Europe. As dengue is a rising pathogen in tropical import diseases, clinicians must be aware of its rare but serious complications.
authors.forename: A-S
authors.initials: AS
authors.lastname: De Koninck
authors.forename: J
authors.initials: J
authors.lastname: Dierick
authors.forename: S
authors.initials: S
authors.lastname: Steyaert
authors.forename: P
authors.initials: P
authors.lastname: Taelman
mesh_terms: D001530:Belgium; D002160:Cambodia; D003715:Dengue / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D014195:Travel; D055815:Young Adult
keywords: Hemophagocytic lymphohistiocytosis,; Hemophagocytic syndrome; Infection-associated hemophagocytic syndrome,; Pancytopenia,; Primary dengue infection,