title: Comparison of flowrates and voided volumes during non-instrumented uroflowmetry and pressure-flow studies in women with stress incontinence.
abstract: OBJECTIVE
  The Blaivas-Groutz nomogram defines voiding obstruction in women using Qmax from the NIF and the maximum detrusor pressure (Pdetmax ) from the PFS. The aim of this study was to understand the relationship between NIF and PFS maximum flow rates in women with stress incontinence.
  
  
  METHODS
  We analyzed the UDS of 597 women with stress-dominant urinary incontinence. Each subject underwent a NIF and then a PFS. Mixed model was used to test the hypothesis that the relationship between flow rates and voided volume (VV) were similar for NIF and PFS.
  
  
  RESULTS
  There were 452 subjects with both NIF and PFS studies that met the inclusion criteria and had max flow rate (Qmax ) for both NIF and PFS. The mean age was 53. Overall, higher VV were observed during PFS compared to NIF and subjects had higher Qmax with NIF compared to PFS. The relationship between Qmax and VV was significantly different between NIF and PFS (P < 0.004). At 200 ml, NIF Qmax was 14% higher than PFS Qmax and this difference increased to 30% at 700 ml.
  
  
  CONCLUSIONS
  The difference between PFS Qmax and NIF Qmax increases as VV increase. As a result, values from PFS and NIF cannot be used interchangeably as has been suggested in the Blaivas-Groutz nomogram for obstruction in women.
authors.affiliation: Department of Urology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois.|Department of Obstetrics and Gynecology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois.
authors.forename: Elizabeth R
authors.initials: ER
authors.lastname: Mueller
authors.affiliation: New England Research Institutes, Watertown, Massachusetts.
authors.forename: Heather
authors.initials: H
authors.lastname: Litman
authors.affiliation: Department of Urology, University of Maryland, Baltimore, Maryland.
authors.forename: Leslie R
authors.initials: LR
authors.lastname: Rickey
authors.affiliation: Department of Urology, William Beaumont Hospital, Royal Oak, Michigan.
authors.forename: Larry
authors.initials: L
authors.lastname: Sirls
authors.affiliation: Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, Utah.
authors.forename: Peggy
authors.initials: P
authors.lastname: Norton
authors.affiliation: Department of Urology, University of Alabama Medical Center, Birmingham, Alabama.
authors.forename: Tracey
authors.initials: T
authors.lastname: Wilson
authors.affiliation: Department of Obstetrics and Gynecology, University of Pittsburgh, Pittsburgh, Pennsylvania.
authors.forename: Pamela
authors.initials: P
authors.lastname: Moalli
authors.affiliation: Department of Urology, University of California, San Diego, California.
authors.forename: Michael
authors.initials: M
authors.lastname: Albo
authors.affiliation: Department of Urology, Southwestern Medical Center, Dallas, Texas.
authors.forename: Philippe
authors.initials: P
authors.lastname: Zimmern
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D016496:Incontinence Pads; D008875:Middle Aged; D056887:Pelvic Organ Prolapse / Q000503:physiopathology / Q000601:surgery; D011312:Pressure; D053825:Suburethral Slings; D014524:Urethral Obstruction / Q000503:physiopathology / Q000601:surgery; D014550:Urinary Incontinence, Stress / Q000503:physiopathology* / Q000601:surgery; D014563:Urodynamics / Q000502:physiology*
keywords: obstruction; pelvic organ prolapse; stress incontinence; urodynamics; uroflowmetry; women