title: Emergence of plasmid-mediated quinolone resistance genes in clinical isolates of Acinetobacter baumannii and Pseudomonas aeruginosa in Henan, China.
abstract: A total of 216 clinical isolates of Acinetobacter baumannii and Pseudomonas aeruginosa were collected from a general hospital in Henan, China, and screened for the plasmid-mediated quinolone resistance (PMQR) determinants. The presence of β-lactamase genes and mutations in quinolone resistance-determining regions were investigated among the PMQR-positive isolates.
authors.affiliation: College of Life Sciences, Henan Normal University, Xinxiang 453007, China.
authors.forename: Xiaobing
authors.initials: X
authors.lastname: Jiang
authors.affiliation: Department of Chemistry and Chemical Engineering, Xinxiang University, Xinxiang 453000, China. Electronic address: yutao7777@hotmail.com.
authors.forename: Tao
authors.initials: T
authors.lastname: Yu
authors.affiliation: College of Chemistry and Molecular Engineering, Henan Provincial Key Laboratory of Chemical Biology and Organic Chemistry, Zhengzhou University, Zhengzhou 450000, China.
authors.forename: Xiaojie
authors.initials: X
authors.lastname: Jiang
authors.affiliation: Department of Chemistry and Chemical Engineering, Xinxiang University, Xinxiang 453000, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Department of Chemistry and Chemical Engineering, Xinxiang University, Xinxiang 453000, China.
authors.forename: Laiping
authors.initials: L
authors.lastname: Zhang
authors.affiliation: College of Life Sciences, Henan Normal University, Xinxiang 453007, China.
authors.forename: Jianmin
authors.initials: J
authors.lastname: Ma
mesh_terms: D000151:Acinetobacter Infections / Q000382:microbiology; D040981:Acinetobacter baumannii / Q000187:drug effects* / Q000302:isolation & purification; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002681:China; D024881:Drug Resistance, Bacterial; D005798:Genes, Bacterial; D006769:Hospitals, General; D006801:Humans; D008826:Microbial Sensitivity Tests; D010957:Plasmids; D011552:Pseudomonas Infections / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000302:isolation & purification; D015363:Quinolones / Q000494:pharmacology*; D001618:beta-Lactamases / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D015363:Quinolones; D001618:beta-Lactamases
keywords: Acinetobacter baumannii; PMQR; Pseudomonas aeruginosa; QRDRs