title: The association between airflow obstruction and radiologic change by tuberculosis.
abstract: BACKGROUND
  Cigarette smoking is the most commonly encountered risk factor for chronic obstructive pulmonary disease (COPD). However, it is not the only one and there is consistent evidence from epidemiologic studies that nonsmokers may develop chronic airflow limitation. A history of tuberculosis has recently been found to be associated with airflow obstruction in adults older than 40 years. The aim of this study was to evaluate the association between the radiologic changes by tuberculosis and airflow obstruction in a population based sample.
  
  
  METHODS
  A nationwide COPD prevalence survey was conducted. We compared the prevalence of airflow obstruction according to the presence of the radiologic change by the tuberculosis.
  
  
  RESULTS
  We analyzed 1,384 subjects who participated in the nationwide Korean COPD survey. All subjects were older than 40 years and took the spirometry and simple chest radiography. We defined the airflow obstruction as FEV1/FVC <0.7. A total of 149 (10.8%) subjects showed airflow obstruction. A total of 167 (12.1%) subjects showed radiologic change by tuberculosis. Among these 167 subjects, 44 (26.3%) had airflow obstruction. For the subjects without radiologic change by tuberculosis, the prevalence of airflow obstruction was only 8.6%. The unadjusted odds ratio for airflow obstruction according to the radiologic change was 3.788 (95% CI: 2.544-5.642).
  
  
  CONCLUSIONS
  The radiologic change by tuberculosis was associated with airflow obstruction.
authors.affiliation: Division of Pulmonology, Allergy & Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Seoul, Republic of Korea.
authors.forename: Yong Il
authors.initials: YI
authors.lastname: Hwang
authors.affiliation: Division of Pulmonology, Allergy & Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Seoul, Republic of Korea.
authors.forename: Joo Hee
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Division of Pulmonology, Allergy & Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Seoul, Republic of Korea.
authors.forename: Chang Youl
authors.initials: CY
authors.lastname: Lee
authors.affiliation: Division of Pulmonology, Allergy & Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Seoul, Republic of Korea.
authors.forename: Sunghoon
authors.initials: S
authors.lastname: Park
authors.affiliation: Division of Pulmonology, Allergy & Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Seoul, Republic of Korea.
authors.forename: Yong Bum
authors.initials: YB
authors.lastname: Park
authors.affiliation: Division of Pulmonology, Allergy & Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Seoul, Republic of Korea.
authors.forename: Seung Hun
authors.initials: SH
authors.lastname: Jang
authors.affiliation: Division of Pulmonology, Allergy & Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Seoul, Republic of Korea.
authors.forename: Cheol Hong
authors.initials: CH
authors.lastname: Kim
authors.affiliation: Division of Pulmonology, Allergy & Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Seoul, Republic of Korea.
authors.forename: Tae Rim
authors.initials: TR
authors.lastname: Shin
authors.affiliation: Division of Pulmonology, Allergy & Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Seoul, Republic of Korea.
authors.forename: Sang Myun
authors.initials: SM
authors.lastname: Park
authors.affiliation: Division of Pulmonology, Allergy & Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Seoul, Republic of Korea.
authors.forename: Yun Su
authors.initials: YS
authors.lastname: Sim
authors.affiliation: Division of Pulmonology, Allergy & Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Seoul, Republic of Korea.
authors.forename: Dong-Gyu
authors.initials: DG
authors.lastname: Kim
authors.affiliation: Division of Pulmonology, Allergy & Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Seoul, Republic of Korea.
authors.forename: Myung-Goo
authors.initials: MG
authors.lastname: Lee
authors.affiliation: Division of Pulmonology, Allergy & Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Seoul, Republic of Korea.
authors.forename: In-Gyu
authors.initials: IG
authors.lastname: Hyun
authors.affiliation: Division of Pulmonology, Allergy & Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Seoul, Republic of Korea.
authors.forename: Ki-Suck
authors.initials: KS
authors.lastname: Jung
keywords: Chronic obstructive pulmonary disease (COPD); airflow obstruction; risk factor; tuberculosis