title: Modeling the effect of different vaccine effectiveness estimates on the number of vaccine-prevented influenza-associated hospitalizations in older adults.
abstract: We compared influenza vaccine-prevented hospitalizations in adults aged ≥65 years for a range of hypothetical effectiveness estimates. During 2012-2013, a vaccine with 10% effectiveness (66% coverage) would have averted approximately 13 000 hospitalizations, and a vaccine with 40% effectiveness would have averted approximately 60 000 hospitalizations. Annual vaccination is merited in this vulnerable population.
authors.affiliation: Influenza Division, Centers for Disease Control and Prevention.
authors.forename: Alicia M
authors.initials: AM
authors.lastname: Fry
authors.affiliation: Influenza Division, Centers for Disease Control and Prevention Battelle Memorial Institute, Atlanta, Georgia.
authors.forename: Inkyu K
authors.initials: IK
authors.lastname: Kim
authors.affiliation: Influenza Division, Centers for Disease Control and Prevention.
authors.forename: Carrie
authors.initials: C
authors.lastname: Reed
authors.affiliation: Influenza Division, Centers for Disease Control and Prevention.
authors.forename: Mark
authors.initials: M
authors.lastname: Thompson
authors.affiliation: Influenza Division, Centers for Disease Control and Prevention.
authors.forename: Sandra S
authors.initials: SS
authors.lastname: Chaves
authors.affiliation: Influenza Division, Centers for Disease Control and Prevention.
authors.forename: Lyn
authors.initials: L
authors.lastname: Finelli
authors.affiliation: Influenza Division, Centers for Disease Control and Prevention.
authors.forename: Joseph
authors.initials: J
authors.lastname: Bresee
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007252:Influenza Vaccines / Q000276:immunology*; D007251:Influenza, Human / Q000276:immunology / Q000517:prevention & control*; D008962:Models, Theoretical; D016896:Treatment Outcome; D014611:Vaccination
chemical_list: D007252:Influenza Vaccines
keywords: hospitalization; influenza; older adults; vaccine effectiveness