title: Permeation redux: thermodynamics and kinetics of ion movement through potassium channels.
abstract: The fundamental biophysics underlying the selective movement of ions through ion channels was launched by George Eisenman in the 1960s, using glass electrodes. This minireview examines the insights from these early studies and the explosive progress made since then.
authors.affiliation: Department of Molecular Physiology and Biophysics, Jefferson Medical College, Philadelphia, Pennsylvania. Electronic address: richardspikehorn@gmail.com.
authors.forename: Richard
authors.initials: R
authors.lastname: Horn
authors.affiliation: Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois.
authors.forename: Benoît
authors.initials: B
authors.lastname: Roux
authors.affiliation: Department of Cell & Molecular Biology, Uppsala University, Biomedical Center, Uppsala, Sweden.
authors.forename: Johan
authors.initials: J
authors.lastname: Åqvist
mesh_terms: D007477:Ions / Q000378:metabolism; D007700:Kinetics; D009068:Movement; D010539:Permeability; D015221:Potassium Channels / Q000737:chemistry / Q000378:metabolism*; D013816:Thermodynamics
chemical_list: D007477:Ions; D015221:Potassium Channels