title: Opsoclonus-myoclonus syndrome associated with human herpes virus-6 rhomboencephalitis.
abstract: Opsoclonus-myoclonus syndrome (OMS) is characterized by opsoclonus and arrhythmic-action myoclonus that predominantly involves the trunk, limbs, and head. Human herpes virus-6 (HHV-6) can rarely cause encephalitis in immunocompetent children and adults. Here we report on a case of OMS associated with HHV-6 rhomboencephalitis. HHV-6 infection should be considered in OMS adults and detection of cell-free viral DNA, indicative of active infection, is mandatory in such cases.
authors.affiliation: Neurology Unit, Department of Medicine, S. Anna Hospital, Como, Italy. Electronic address: vincenzobelcastro@libero.it.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Belcastro
authors.affiliation: Neurology Unit, Department of Medicine, S. Anna Hospital, Como, Italy.
authors.forename: Mirko
authors.initials: M
authors.lastname: Piola
authors.affiliation: Department of Biomedical Sciences for Health, University of Milan, Milan, Italy.
authors.forename: Sandro
authors.initials: S
authors.lastname: Binda
authors.affiliation: Department of Medicine, S. Anna Hospital, Como, Italy.
authors.forename: Domenico
authors.initials: D
authors.lastname: Santoro
authors.affiliation: Neurology Unit, Department of Medicine, S. Anna Hospital, Como, Italy.
authors.forename: Monica
authors.initials: M
authors.lastname: Rezzonico
authors.affiliation: Neurology Unit, Department of Medicine, S. Anna Hospital, Como, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Arnaboldi
mesh_terms: D018792:Encephalitis, Viral / Q000150:complications*; D015654:Herpesvirus 6, Human / Q000472:pathogenicity*; D006801:Humans; D008297:Male; D008875:Middle Aged; D053578:Opsoclonus-Myoclonus Syndrome / Q000209:etiology* / Q000821:virology*; D014786:Vision Disorders / Q000209:etiology / Q000821:virology
keywords: Human herpes virus-6 infection; Opsoclonus–myoclonus syndrome; Rhomboencephalitis