title: Gap size and wall lesion development next to composite.
abstract: This in situ study investigated whether there is a relationship between gap size and wall lesion development in dentin next to 2 composite materials, and whether a clinically relevant threshold for the gap size could be established. For 21 days, 14 volunteers wore a modified occlusal splint containing human dentin samples with 5 different interfaces: 4 gaps of 50 µm, 100 µm, 200 µm, or 400 µm and 1 non-bonded interface without a gap. Eight times a day, the splint with samples was dipped in a 20% sucrose solution for 10 minutes. Before and after caries development, specimens were imaged with transversal wavelength-independent microradiography (T-WIM), and lesion depth (LD) and mineral loss (ML) were calculated at the 5 different interfaces. After correction for the confounder location (more mesial or distal), a paired t test clustered within volunteers was performed for comparison of gap widths. Results showed no trend for a relationship between the corrected lesion depth and the gap size. None of the differences in lesion depth for the different gap sizes was statistically significant. Also, the composite material (AP-X or Filtek Supreme) gave no statistically significant differences in lesion depth and mineral loss. A minimum gap size could not be established, although, in a non-bonded interface without a measurable gap, wall lesion development was never observed.
authors.affiliation: College of Dental Sciences, Department of Preventive and Restorative Dentistry, Radboud University Medical Center, the Netherlands Nicolien.Kuper@radboudumc.nl.
authors.forename: N K
authors.initials: NK
authors.lastname: Kuper
authors.affiliation: College of Dental Sciences, Department of Preventive and Restorative Dentistry, Radboud University Medical Center, the Netherlands.
authors.forename: N J M
authors.initials: NJ
authors.lastname: Opdam
authors.affiliation: College of Dental Sciences, Department of Preventive and Restorative Dentistry, Radboud University Medical Center, the Netherlands.
authors.forename: J L
authors.initials: JL
authors.lastname: Ruben
authors.affiliation: Department of Preventive Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University, Amsterdam, the Netherlands.
authors.forename: J J
authors.initials: JJ
authors.lastname: de Soet
authors.affiliation: Federal University of Pelotas, School of Dentistry, Gonçalves Chaves, 457, 5th floor, Pelotas, 96015560, Brazil.
authors.forename: M S
authors.initials: MS
authors.lastname: Cenci
authors.affiliation: College of Dental Sciences, Department of Preventive and Restorative Dentistry, Radboud University Medical Center, the Netherlands.
authors.forename: E M
authors.initials: EM
authors.lastname: Bronkhorst
authors.affiliation: College of Dental Sciences, Department of Preventive and Restorative Dentistry, Radboud University Medical Center, the Netherlands.
authors.forename: M C D N J M
authors.initials: MC
authors.lastname: Huysmans
mesh_terms: D000328:Adult; D002326:Cariogenic Agents / Q000009:adverse effects; D003188:Composite Resins / Q000737:chemistry*; D003731:Dental Caries / Q000209:etiology*; D018772:Dental Marginal Adaptation; D003764:Dental Materials / Q000737:chemistry*; D003793:Dental Restoration, Permanent; D003804:Dentin / Q000737:chemistry / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008297:Male; D008422:Materials Testing; D008689:Methacrylates / Q000737:chemistry; D008852:Microradiography / Q000379:methods; D008875:Middle Aged; D008903:Minerals / Q000032:analysis; D019279:Resin Cements / Q000737:chemistry; D013395:Sucrose / Q000009:adverse effects; D013499:Surface Properties; D055815:Young Adult
chemical_list: D002326:Cariogenic Agents; C112828:Clearfil AP-X; D003188:Composite Resins; D003764:Dental Materials; C474035:Filtek Supreme; D008689:Methacrylates; D008903:Minerals; D019279:Resin Cements; D013395:Sucrose
keywords: Transversal Wavelength Independent Microradiography; composite resin restorations; lesion depth; mineral loss; recurrent caries; secondary caries