title: Development of a new rhodamine-based FRET platform and its application as a Cu2+ probe.
abstract: We have constructed a new rhodamine-based FRET platform, which was then used to develop a ratiometric fluorescent Cu(2+) probe. The novel Cu(2+) probe exhibits several favorable features including a large variation in the emission ratio, well-resolved emission peaks, high sensitivity, and high selectivity. Importantly, it is suitable for fluorescence imaging in living cells.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, P. R. China. weiyinglin2013@163.com.
authors.forename: Xiaoyu
authors.initials: X
authors.lastname: Guan
authors.forename: Weiying
authors.initials: W
authors.lastname: Lin
authors.forename: Weimin
authors.initials: W
authors.lastname: Huang
mesh_terms: D003300:Copper / Q000737:chemistry*; D031541:Fluorescence Resonance Energy Transfer; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006801:Humans; D006868:Hydrolysis; D061986:MCF-7 Cells; D012235:Rhodamines / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D012235:Rhodamines; D003300:Copper