title: Bone marrow mononuclear cell therapy for acute myocardial infarction: a perspective from the cardiovascular cell therapy research network.
abstract: To understand the role of bone marrow mononuclear cells in the treatment of acute myocardial infarction, this overview offers a retrospective examination of strengths and limitations of 3 contemporaneous trials with attention to critical design features and provides an analysis of the combined data set and implications for future directions in cell therapy for acute myocardial infarction.
authors.affiliation: From Mayo Clinic, Rochester, MN (R.D.S., D.B.S.); University of Florida School of Medicine, Gainesville (C.J.P., R.D.A.); Minneapolis Heart Institute at Abbott Northwestern Hospital, University of Minnesota School of Medicine (J.H.T.); Cedars-Sinai Heart Institute, Los Angeles, CA (T.D.H.); University of Louisville School of Medicine, KY (R.B.); The University of Texas MD Anderson Cancer Center, Houston (E.Y.); University of Miami Miller School of Medicine, FL (J.M.H., I.H.S.); Florida Hospital Tampa Pepin Heart Institute (C.L.); University of Texas Health Science Center School of Public Health, Houston (S.L.S., L.A.M.); Texas Heart Institute, Houston (D.A.T.); and National Heart, Lung, and Blood Institute, Bethesda, MD (R.F.E.).
authors.forename: Robert D
authors.initials: RD
authors.lastname: Simari
authors.forename: Carl J
authors.initials: CJ
authors.lastname: Pepine
authors.forename: Jay H
authors.initials: JH
authors.lastname: Traverse
authors.forename: Timothy D
authors.initials: TD
authors.lastname: Henry
authors.forename: Roberto
authors.initials: R
authors.lastname: Bolli
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Spoon
authors.forename: Ed
authors.initials: E
authors.lastname: Yeh
authors.forename: Joshua M
authors.initials: JM
authors.lastname: Hare
authors.forename: Ivonne Hernandez
authors.initials: IH
authors.lastname: Schulman
authors.forename: R David
authors.initials: RD
authors.lastname: Anderson
authors.forename: Charles
authors.initials: C
authors.lastname: Lambert
authors.forename: Shelly L
authors.initials: SL
authors.lastname: Sayre
authors.forename: Doris A
authors.initials: DA
authors.lastname: Taylor
authors.forename: Ray F
authors.initials: RF
authors.lastname: Ebert
authors.forename: Lemuel A
authors.initials: LA
authors.lastname: Moyé
mesh_terms: D016026:Bone Marrow Transplantation / Q000379:methods* / Q000639:trends; D064987:Cell- and Tissue-Based Therapy / Q000379:methods / Q000639:trends; D002986:Clinical Trials as Topic / Q000379:methods / Q000639:trends; D016208:Databases, Factual / Q000639:trends; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000473:pathology / Q000502:physiology / Q000637:transplantation*; D009203:Myocardial Infarction / Q000473:pathology* / Q000601:surgery*; D012189:Retrospective Studies; D013318:Stroke Volume / Q000502:physiology; D016896:Treatment Outcome
keywords: diagnostic imaging; myocardial infarction; population