title: Peak oxygen uptake test in the assessment of growth hormone deficiency.
abstract: This study aimed at evaluating a peak oxygen uptake test as a simple diagnostic tool to assess growth-hormone deficiency (GHD) in adults. Based on the findings of multiple growth hormone (GH) samplings after the exercise, a single GH sample taken 15 min postexercise revealed high accuracy in the diagnosis of GHD in the present study. A standardized peak oxygen uptake test may, therefore, provide an accurate alternative to more invasive tests of GHD.
authors.affiliation: Division of Endocrinology, Diabetes and Clinical Nutrition, Inselspital, Bern University Hospital, and University of Bern, CH-3010 Bern, Switzerland.
authors.forename: Thomas
authors.initials: T
authors.lastname: Zueger
authors.forename: Julie
authors.initials: J
authors.lastname: Bucher
authors.forename: Emanuel R
authors.initials: ER
authors.lastname: Christ
authors.forename: Christoph
authors.initials: C
authors.lastname: Stettler
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003677:Deficiency Diseases / Q000175:diagnosis / Q000378:metabolism; D019382:Human Growth Hormone / Q000172:deficiency*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000378:metabolism*; D011446:Prospective Studies
chemical_list: D019382:Human Growth Hormone; D010100:Oxygen
keywords: V̇O2peak test; analyse de fonction d’efficacité du récepteur (FER); diagnostic accuracy; diagnostic test; déficience en hormone de croissance; growth hormone deficiency; growth hormone secretion; précision du diagnostic; receiver operating characteristics (ROC) analysis; sécrétion de l’hormone de croissance; test diagnostique; test du V̇O2 de pointe