title: Prophylaxis of contrast-induced nephrotoxicity.
abstract: Contrast-induced nephrotoxicity (CIN) is a form of acute kidney injury that follows intravascular contrast media exposure. CIN may be preventable because its risk factors are well established and the timing of renal insult is commonly known in advance. However, contrast-induced nephrotoxicity is still the third leading cause of iatrogenic renal failure. This important complication accounts up to 10% of acute renal failure cases in hospitalized patients and it is associated with increased short- and long-term morbidity and mortality. Prolonged hospitalization follows and overall increases healthcare resource utilization. This paper will discuss the various prophylactic procedures tested in clinical trials.
authors.affiliation: Division of Nephrology, Internal Medicine I, University of Ulm, Albert-Einstein Allee 23, 89081 Ulm, Germany.
authors.forename: Ulla
authors.identifier: 0000-0003-3558-3886
authors.initials: U
authors.lastname: Ludwig
authors.affiliation: Division of Nephrology, Internal Medicine I, University of Ulm, Albert-Einstein Allee 23, 89081 Ulm, Germany.
authors.forename: Frieder
authors.identifier: 0000-0001-9280-3334
authors.initials: F
authors.lastname: Keller
mesh_terms: D000818:Animals; D003287:Contrast Media / Q000009:adverse effects*; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced* / Q000517:prevention & control*; D012307:Risk Factors
chemical_list: D003287:Contrast Media