title: Tic-TACs: refreshing hair growth.
abstract: Although stem cells are subject to niche control, evidence is emerging that they also contribute to generating the niche through their offspring. Using the hair follicle as a model, Hsu at al. demonstrate that the transient-amplifying cells, downstream of stem cells and well-known cell producers, signal back to stem cells to maintain long-term regenerative capacity.
authors.affiliation: Center for Regenerative Medicine, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA; Harvard Stem Cell Institute and Harvard University Department of Stem Cell and Regenerative Biology, 7 Divinity Avenue, Cambridge, MA 02138, USA. Electronic address: dkalaitzidis@partners.org.
authors.forename: Demetrios
authors.initials: D
authors.lastname: Kalaitzidis
authors.affiliation: Center for Regenerative Medicine, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA; Harvard Stem Cell Institute and Harvard University Department of Stem Cell and Regenerative Biology, 7 Divinity Avenue, Cambridge, MA 02138, USA. Electronic address: david_scadden@harvard.edu.
authors.forename: David T
authors.initials: DT
authors.lastname: Scadden
mesh_terms: D000818:Animals; D006197:Hair / Q000166:cytology* / Q000502:physiology*; D018859:Hair Follicle / Q000166:cytology*; D055153:Stem Cell Niche; D013234:Stem Cells / Q000166:cytology*