title: Synthesis of metal complexes involving Schiff base ligand with methylenedioxy moiety: spectral, thermal, XRD and antimicrobial studies.
abstract: Metal complexes of Zn(II), Cd(II), Ni(II), Cu(II), Fe(III), Co(II), Mn(II) Hg(II), and Ag(I) have been synthesized from Schiff base ligand, prepared by the condensation of 3,4-(methylenedioxy)aniline and 5-bromo salicylaldehyde. All the compounds have been characterized by using elemental analysis, molar conductance, FT-IR, UV-Vis, (1)H NMR, (13)C NMR, mass spectra, powder XRD and thermal analysis (TG/DTA) technique. The elemental analysis suggests the stoichiometry to be 1:1 (metal:ligand). The FT-IR, (1)H NMR, (13)C NMR and UV-Vis spectral data suggest that the ligand coordinate to the metal atom by imino nitrogen and phenolic oxygen as bidentate manner. Mass spectral data further support the molecular mass of the compounds and their structure. Powder XRD indicates the crystalline state and morphology of the ligand and its metal complexes. The thermal behaviors of the complexes prove the presence of lattice as well as coordinated water molecules in the complexes. Melting point supports the thermal stability of all the compounds. The in vitro antimicrobial effects of the synthesized compounds were tested against five bacterial and three fungal species by well diffusion method. Antioxidant activities have also been performed for all the compounds. Metal complexes show more biological activity than the Schiff base.
authors.affiliation: Chemistry Section, Faculty of Engineering and Technology, Annamalai University, Annamalai Nagar 608002, Tamil Nadu, India.
authors.forename: M L
authors.initials: ML
authors.lastname: Sundararajan
authors.affiliation: Chemistry Section, Faculty of Engineering and Technology, Annamalai University, Annamalai Nagar 608002, Tamil Nadu, India. Electronic address: jeyasundarligand@rediffmail.com.
authors.forename: T
authors.initials: T
authors.lastname: Jeyakumar
authors.affiliation: Chemistry Section, Faculty of Engineering and Technology, Annamalai University, Annamalai Nagar 608002, Tamil Nadu, India.
authors.forename: J
authors.initials: J
authors.lastname: Anandakumaran
authors.affiliation: Department of Biotechnology, Anna University, Trichy 620024, Tamil Nadu, India.
authors.forename: B
authors.initials: B
authors.lastname: Karpanai Selvan
mesh_terms: D000447:Aldehydes / Q000737:chemistry* / Q000494:pharmacology; D000814:Aniline Compounds / Q000737:chemistry* / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy; D056831:Coordination Complexes / Q000737:chemistry* / Q000494:pharmacology; D005658:Fungi / Q000187:drug effects; D006801:Humans; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D019216:Metals, Heavy / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009181:Mycoses / Q000188:drug therapy; D012545:Schiff Bases / Q000737:chemistry* / Q000494:pharmacology; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D000447:Aldehydes; D000814:Aniline Compounds; D000890:Anti-Infective Agents; D000975:Antioxidants; D056831:Coordination Complexes; D008024:Ligands; D019216:Metals, Heavy; D012545:Schiff Bases; C013243:salicylaldehyde
keywords: 3,4-(Methylenedioxy) aniline; 5-Bromo salicylaldehyde; Schiff base metal complexes