title: Identifying environmental antigens that activate myelin-specific T cells.
abstract: Human genetic and environmental factors underlie susceptibility to the T cell-mediated autoimmune disease, multiple sclerosis (MS). How the environment influences the pathogenesis of MS has been difficult to parse. A recent paper in Cell shows that environmental antigens that activate myelin-specific T cells can be identified with unprecedented accuracy.
authors.affiliation: Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
authors.forename: Brian D
authors.initials: BD
authors.lastname: Stadinski
authors.affiliation: Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA. Electronic address: Eric.Huseby@umassmed.edu.
authors.forename: Eric S
authors.initials: ES
authors.lastname: Huseby
mesh_terms: D000818:Animals; D006801:Humans; D010455:Peptides / Q000737:chemistry*; D011948:Receptors, Antigen, T-Cell / Q000737:chemistry*; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D010455:Peptides; D011948:Receptors, Antigen, T-Cell