title: Maternal and perinatal outcomes of eclampsia with and without HELLP syndrome in a teaching hospital in western Turkey.
abstract: In this study, we compared the perinatal and maternal outcomes of women with eclampsia with and without HELLP syndrome. A total of 219 pregnancies complicated by eclampsia with and without HELLP syndrome managed between January 2002 and December 2011, were reviewed. The incidence of eclampsia was 1.7/1,000 deliveries. Among 219 patients with eclampsia, 141 (64.4%) did not develop HELLP syndrome and 78 (35.6%) did develop HELLP syndrome. Maternal age and the rates of nulliparity were similar in both groups. Interval time from eclamptic seizure to delivery was significantly longer in the without-HELLP syndrome group (0.92 ± 0.29 weeks vs 0.16 ± 0.12 weeks, p = 0.028). Furthermore, overall perinatal mortality (particularly after gestational week 32) was significantly higher in the with-HELLP syndrome group (20.5% vs 9.9%, p = 0.029). In conclusion, patients with HELLP syndrome had significantly higher perinatal mortality than those with eclampsia without HELLP syndrome and no regular prenatal care.
authors.affiliation: Department of Obstetrics and Gynecology, Şişli Etfal Training and Research Hospital , İstanbul.
authors.forename: O
authors.initials: O
authors.lastname: Asıcıoglu
authors.forename: K
authors.initials: K
authors.lastname: Güngördük
authors.forename: G
authors.initials: G
authors.lastname: Yildirim
authors.forename: H
authors.initials: H
authors.lastname: Aslan
authors.forename: T
authors.initials: T
authors.lastname: Günay
mesh_terms: D000328:Adult; D005260:Female; D017359:HELLP Syndrome / Q000453:epidemiology*; D006784:Hospitals, Teaching / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D007226:Infant Mortality; D007231:Infant, Newborn; D054238:Perinatal Mortality; D011225:Pre-Eclampsia / Q000453:epidemiology*; D011247:Pregnancy; D012189:Retrospective Studies; D014421:Turkey / Q000453:epidemiology; D055815:Young Adult