title: Akt: a new activation mechanism.
abstract: Akt phosphorylation at S473 and T308 has been believed to be the prerequisites for its activation for years. Now, new phosphorylation event on Akt is identified and can trigger Akt activation and lead to its downstream oncogenic events.
authors.affiliation: 1] Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA [2] The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX 77030, USA.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Gao
authors.affiliation: 1] Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA [2] Department of Primary Care Health Sciences, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 9DU, UK.
authors.forename: Asad
authors.initials: A
authors.lastname: Moten
authors.affiliation: 1] Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA [2] The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX 77030, USA [3] Graduate Institute of Basic Medical Science, China Medical University, Taichung 404 [4] Department of Biotechnology, Asia University, Taichung 404.
authors.forename: Hui-Kuan
authors.initials: HK
authors.lastname: Lin
mesh_terms: D000818:Animals; D002453:Cell Cycle / Q000502:physiology*; D008297:Male; D051057:Proto-Oncogene Proteins c-akt / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D051057:Proto-Oncogene Proteins c-akt