title: Evaluation of the relationship between renal function and renal volume-vascular indices using 3D power Doppler ultrasound.
abstract: OBJECTIVE
  To investigate the relationship between renal function and total renal volume-vascular indices using 3D power Doppler ultrasound (3DPDUS).
  
  
  METHODS
  One hundred six patients with hypertensive proteinuric nephropathy (HPN) (49 male, 57 female) and 65 healthy controls (32 male, 33 female) were evaluated prospectively using 3DPDUS. Total renal volume (RV), vascularization index (VI), flow index (FI) and vascularization flow index (VFI) were calculated using Virtual Organ Computer-aided Analysis (VOCAL). The estimated glomerular filtration rates (GFRs) of the patients with HPN and the control group were calculated. The patients with HPN were divided into two groups on the basis of GFR, normal (≥90) or reduced (<90). Differences between groups were compared using ANOVA. Correlations between GFR, renal volume and vascular indices were analyzed using Pearson's correlation analysis. Significance was set at p<0.05.
  
  
  RESULTS
  The mean total RV, VI, FI and VFI values in the reduced GFR, normal GFR and control groups were RV (ml): 234.7, 280.7 and 294.6; VI: 17.6, 27.6 and 46.8; FI: 79.1, 88.7 and 93.9 and VFI: 7.1, 12.7 and 23.8. There were statistically significant differences between the groups (p<0.001). Total RVs and vascular indices exhibited significant correlations with estimated GFR (r=0.53-0.59, p<0.001) CONCLUSION: Three-dimensional power Doppler ultrasound is a reliable predictive technique in renal function analysis.
authors.affiliation: Karadeniz Technical University Faculty of Medicine, Farabi Hospital, Department of Radiology, 61080 Trabzon, Turkey. Electronic address: drcansu@gmail.com.
authors.forename: Aysegul
authors.initials: A
authors.lastname: Cansu
authors.affiliation: Karadeniz Technical University Faculty of Medicine, Farabi Hospital, Department of Radiology, 61080 Trabzon, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Kupeli
authors.affiliation: Karadeniz Technical University Faculty of Medicine, Farabi Hospital, Department of Radiology, 61080 Trabzon, Turkey.
authors.forename: Sibel
authors.initials: S
authors.lastname: Kul
authors.affiliation: Karadeniz Technical University Faculty of Medicine, Farabi Hospital, Department of Radiology, 61080 Trabzon, Turkey.
authors.forename: Ilker
authors.initials: I
authors.lastname: Eyuboglu
authors.affiliation: Karadeniz Technical University Faculty of Medicine, Farabi Hospital, Department of Radiology, 61080 Trabzon, Turkey.
authors.forename: Sukru
authors.initials: S
authors.lastname: Oguz
authors.affiliation: Karadeniz Technical University Faculty of Medicine, Farabi Hospital, Department of Radiology, 61080 Trabzon, Turkey.
authors.forename: Mehmet Halil
authors.initials: MH
authors.lastname: Ozturk
authors.affiliation: Karadeniz Technical University Faculty of Medicine, Farabi Hospital, Department of Radiology, 61080 Trabzon, Turkey.
authors.forename: Hasan
authors.initials: H
authors.lastname: Dinc
mesh_terms: D000328:Adult; D005919:Glomerular Filtration Rate; D006801:Humans; D006977:Hypertension, Renal / Q000150:complications / Q000175:diagnosis*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009400:Nephrosclerosis / Q000175:diagnosis* / Q000209:etiology; D015588:Observer Variation; D009929:Organ Size; D011507:Proteinuria / Q000175:diagnosis* / Q000209:etiology; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018608:Ultrasonography, Doppler / Q000379:methods*
keywords: Renal function; Renal volume; Three-dimensional power Doppler ultrasound; VOCAL