title: Composite artificial semi-knee joint system.
abstract: OBJECTIVE
  The purpose of the study was to investigate the clinical implantation protocol of custom-made artificial semi-knee joint based on computer-aided design so as to improve the limb salvage efficiency.
  
  
  METHODS
  The custom-made artificial semi-knee joint was designed and manufactured based on rapid prototyping technology. The repeated modifications were carried out in the design and manufacture of the semi-knee joint, together with the operation protocol. Clinical trial was conducted on 2 cases of osteosarcoma, one receiving allograft prosthesis composite transplantation, and the other receiving synthetic bone graft prosthesis composite transplantation. The clinical outcomes of the 2 patients were evaluated.
  
  
  RESULTS
  The custom-made artificial semi-knee joint met the clinical customization needs. In clinical trial, 18-month follow-up demonstrated the satisfactory knee joint function recovery in near future.
  
  
  CONCLUSIONS
  The custom-made artificial semi-knee joint based on computer-aided design can afford satisfactory knee joint function recovery following allograft bone transplantation.
authors.affiliation: Department of Orthopaedics, No. 161 Hospital of PLA, Wuhan, China. lizhi301@163.com.
authors.forename: Z
authors.initials: Z
authors.lastname: Li
authors.forename: S-F
authors.initials: SF
authors.lastname: Xu
authors.forename: D-C
authors.initials: DC
authors.lastname: Li
authors.forename: Z
authors.initials: Z
authors.lastname: Sun
authors.forename: T
authors.initials: T
authors.lastname: Zhang
authors.forename: J-X
authors.initials: JX
authors.lastname: Lu
authors.forename: Z
authors.initials: Z
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000818:Animals; D019645:Arthroplasty, Replacement, Knee / Q000295:instrumentation*; D001858:Bone Nails; D016025:Bone Transplantation; D017076:Computer-Aided Design; D005260:Female; D005266:Femoral Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D007720:Knee Prosthesis; D008297:Male; D008422:Materials Testing; D023421:Models, Animal; D012516:Osteosarcoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D011474:Prosthesis Design; D011859:Radiography; D020127:Recovery of Function; D013977:Tibia / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome