title: Affective lability in patients with bipolar disorders is associated with high levels of childhood trauma.
abstract: This study aimed to investigate associations between a history of childhood trauma and levels of affective lability in bipolar patients compared to controls. Forty-two patients and 14 controls were assessed using the Affective Lability Scale (ALS) and the Childhood Trauma Questionnaire (CTQ). Affective Lability Score was significantly associated with scores on the Childhood Trauma Questionnaire. A multivariate regression model indicated a relationship between childhood trauma scores and differences in affective lability between patients and controls.
authors.affiliation: NORMENT, Institute of Clinical Medicine, University of Oslo, Norway; Psychosis Research Unit, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway. Electronic address: monica.aas@medisin.uio.no.
authors.forename: Monica
authors.initials: M
authors.lastname: Aas
authors.affiliation: Psychosis Research Unit, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway; Department of Specialized Inpatient Treatment, Akershus University Hospital, Norway.
authors.forename: Sofie R
authors.initials: SR
authors.lastname: Aminoff
authors.affiliation: Psychosis Research Unit, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
authors.forename: Trine
authors.initials: T
authors.lastname: Vik Lagerberg
authors.affiliation: AP-HP, Hôpital H. Mondor - A. Chenevier, Pôle de Psychiatry, Créteil 94000, France; Inserm, U955, Créteil 94000, France; Fondation Fondamental, Créteil, France; ENBREC, European Network of Bipolar Research Expert Centres (ENBREC), Paris, France.
authors.forename: Bruno
authors.initials: B
authors.lastname: Etain
authors.affiliation: NORMENT, Institute of Clinical Medicine, University of Oslo, Norway; Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway.
authors.forename: Ingrid
authors.initials: I
authors.lastname: Agartz
authors.affiliation: NORMENT, Institute of Clinical Medicine, University of Oslo, Norway; Psychosis Research Unit, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway; ENBREC, European Network of Bipolar Research Expert Centres (ENBREC), Paris, France.
authors.forename: Ole A
authors.initials: OA
authors.lastname: Andreassen
authors.affiliation: NORMENT, Institute of Clinical Medicine, University of Oslo, Norway; Psychosis Research Unit, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
authors.forename: Ingrid
authors.initials: I
authors.lastname: Melle
mesh_terms: D000293:Adolescent; D000328:Adult; D054523:Adult Survivors of Child Abuse / Q000523:psychology*; D000339:Affect; D000368:Aged; D001714:Bipolar Disorder / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D011795:Surveys and Questionnaires; D055815:Young Adult
keywords: Affective Lability Scale (ALS); Bipolar disorders; Childhood Trauma Questionnaire (CTQ)