title: The role of sentinel node biopsy in male breast cancer.
abstract: BACKGROUND
  Sentinel lymph node biopsy (SLNB) is a standard procedure in women with breast cancer. The risk of morbidity related to axillary lymph node dissection (ALND) is similar for men and women with breast cancer and SLNB could minimize this risk.
  
  
  METHODS
  Between January 2004 and August 2013, 25 men with primary breast cancer were operated on at the Bács-Kiskun County Teaching Hospital. These were reviewed retrospectively. SLNB was performed following lymphoscintigraphy with intraoperative gamma probe detection and blue dye mapping.
  
  
  RESULTS
  SLNB was successful in all 16 male patients (100 %), in whom it was attempted. The SLNs were negative in 4 cases (25 %) and were involved in 12. Intraoperative imprint cytology was positive in 9 of the 12 involved cases (75 %) and resulted immediate completion ALND. In 7 patients, the intraoperative imprint cytology was negative, with 3 false-negative results that resulted in delayed completion ALND. After a median follow-up of 48 months, there was only one axillary recurrence after ALND and none in the SLNB group.
  
  
  CONCLUSIONS
  SLNB is successful and accurate in male breast cancer patients too. Although compared to women a larger proportion of men have positive nodes, for men with negative nodes, ALND-related morbidity may be reduced by SLNB. We recommend SLNB in male patients with breast cancer and clinically negative axilla.
authors.affiliation: Department of Surgery, Bács-Kiskun County Teaching Hospital, Nyíri út 38, Kecskemet, 6000, Hungary. marazrobert2010@gmail.com.|Department of Oncology, Bács-Kiskun County Teaching Hospital, Nyíri út 38, Kecskemet, 6000, Hungary. marazrobert2010@gmail.com.
authors.forename: Róbert
authors.initials: R
authors.lastname: Maráz
authors.affiliation: Department of Surgery, Bács-Kiskun County Teaching Hospital, Nyíri út 38, Kecskemet, 6000, Hungary.
authors.forename: Gábor
authors.initials: G
authors.lastname: Boross
authors.affiliation: Department of Surgery, Bács-Kiskun County Teaching Hospital, Nyíri út 38, Kecskemet, 6000, Hungary.
authors.forename: József
authors.initials: J
authors.lastname: Pap-Szekeres
authors.affiliation: Department of Surgery, Bács-Kiskun County Teaching Hospital, Nyíri út 38, Kecskemet, 6000, Hungary.
authors.forename: László
authors.initials: L
authors.lastname: Markó
authors.affiliation: Department of Nuclear Medicine, Bács-Kiskun County Teaching Hospital, Nyíri út 38, Kecskemet, 6000, Hungary.
authors.forename: Mária
authors.initials: M
authors.lastname: Rajtár
authors.affiliation: Department of Breast Diagnostics, Mamma Zrt at the Bács-Kiskun County Teaching Hospital, Nyíri út 38, Kecskemet, 6000, Hungary.
authors.forename: Éva
authors.initials: É
authors.lastname: Ambrózay
authors.affiliation: Department of Pathology, Bács-Kiskun County Teaching Hospital, Nyíri út 38, Kecskemet, 6000, Hungary.
authors.forename: Rita
authors.initials: R
authors.lastname: Bori
authors.affiliation: Department of Pathology, Bács-Kiskun County Teaching Hospital, Nyíri út 38, Kecskemet, 6000, Hungary.|Department of Pathology, University of Szeged, Szeged, Hungary.
authors.forename: Gábor
authors.initials: G
authors.lastname: Cserni
mesh_terms: D000368:Aged; D001365:Axilla; D018567:Breast Neoplasms, Male / Q000473:pathology / Q000601:surgery*; D018270:Carcinoma, Ductal, Breast / Q000473:pathology / Q000601:surgery*; D018275:Carcinoma, Lobular / Q000473:pathology / Q000601:surgery*; D015331:Cohort Studies; D004396:Coloring Agents; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology*; D061305:Lymphoscintigraphy; D008297:Male; D008408:Mastectomy / Q000379:methods*; D015412:Mastectomy, Segmental / Q000379:methods; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*
chemical_list: D004396:Coloring Agents
keywords: Axillary block dissection; Male breast cancer; Sentinel lymph node biopsy