title: The effect of topical mometasone furoate nasal spray on carriage of Staphylococcus aureus.
abstract: OBJECTIVE
  This study aims to examine the effect of topical mometasone furoate nasal spray on nasal Staphylococcus aureus (S. aureus) colonization in the treatment of allergic rhinitis.
  
  
  METHODS
  Between January 2012 and February 2013, 53 patients having perennial allergic rhinitis symptoms (37 females, 16 males) and 53 healthy controls (36 females, 17 males) were included in the study. Nasal cultures were obtained and evaluated before and after the treatment in allergic rhinitis patients who were admitted to the ear, nose and throat (ENT) outpatient clinic and receiving a mometasone furoate nasal spray treatment (200 mcg/day) once a day for one-month. In healthy controls, nasal cultures were obtained and evaluated once.
  
  
  RESULTS
  In allergic rhinitis patients, five cultures were positive for S. aureus before the treatment while the number of cultures positive for S. aureus was six after the treatment. There was no significant difference in the pre-treatment and post-treatment S. aureus colonization between the patient group and controls (p>0.05).
  
  
  CONCLUSIONS
  Mometasone furoate nasal spray used in the treatment of allergic rhinitis appears to be ineffective for nasal S. aureus colonization.
authors.affiliation: Department of Otolaryngology, Elazığ Training and Research Hospital, 23100 Elazığ, Turkey. drcahitpolat@yahoo.com.
authors.forename: Cahit
authors.initials: C
authors.lastname: Polat
authors.forename: Elif Bilge
authors.initials: EB
authors.lastname: Uysal
authors.forename: Salim
authors.initials: S
authors.lastname: Yüce
authors.forename: Ismail Onder
authors.initials: IO
authors.lastname: Uysal
authors.forename: Sema
authors.initials: S
authors.lastname: Koç
mesh_terms: D000281:Administration, Intranasal; D000293:Adolescent; D000328:Adult; D000368:Aged; D018926:Anti-Allergic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D002353:Carrier State / Q000188:drug therapy* / Q000382:microbiology; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000068656:Mometasone Furoate; D059085:Nasal Sprays; D011244:Pregnadienediols / Q000008:administration & dosage / Q000494:pharmacology*; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy* / Q000382:microbiology; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects*; D055815:Young Adult
chemical_list: D018926:Anti-Allergic Agents; D059085:Nasal Sprays; D011244:Pregnadienediols; D000068656:Mometasone Furoate