title: Successful management of bilateral refractory chylothorax after double lung transplantation for lymphangioleiomyomatosis.
abstract: Lymphangioleiomyomatosis (LAM) is a rare disease that leads to airways and lymphatic channels obstruction due to abnormal smooth muscle proliferation. It presents with dyspnea, pneumothorax or chylothorax. Lung transplantation (LT) has emerged as a valuable therapeutic option with limited reports. We report a case of LAM that underwent double LT and complicated by refractory bilateral chylothorax which was managed successfully by povidone-iodine pleurodesis and the addition of sirolimus to the post-transplantation immunosuppressive therapy. The patient has no recurrence with 24 months follow-up.
authors.affiliation: Department of Surgery, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia ; Department of Cardiothoracic Surgery, Ain Shams University, Cairo, Egypt.
authors.forename: Mohammed
authors.initials: M
authors.lastname: Hussein
authors.affiliation: Department of Surgery, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
authors.forename: Yasser M
authors.initials: YM
authors.lastname: Aljehani
authors.affiliation: Department of Surgery, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
authors.forename: Imran
authors.initials: I
authors.lastname: Nizami
authors.affiliation: Department of Surgery, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
authors.forename: Waleed
authors.initials: W
authors.lastname: Saleh
keywords: Chylothorax; lung transplantation; lymphangioleiomyomatosis; pleurodesis; povidone iodine