title: A study on Borna disease virus infection in domestic cats in Japan.
abstract: Borna disease virus (BDV) infection causes neurological disease in cats. Here, we report BDV infection in 199 hospitalized domestic cats in the Tokyo area. BDV infection was evaluated by detection of plasma antibodies against BDV-p24 or -p40. BDV-specific antibodies were detected in 54 cats (27.1%). Interestingly, the percentage of seropositive cats was not significantly different among the three clinical groups, i.e., healthy (29.8%), neurologically asymptomatic disease (22.2%) and neurological disease (33.3%). The specific antibodies were present even in cats aged below one year. The seropositive ratio was constant, irrespective of age and sampling season. The present study suggests that additional factors are required for onset of Borna disease in naturally infected cats and that BDV is transmitted through vertical routes in cats.
authors.affiliation: Department of Animal Medical Sciences, Faculty of Life Sciences, Kyoto Sangyo University, Motoyama, Kamigamo, Kita-ku, Kyoto 603-8555, Japan.
authors.forename: Azusa
authors.initials: A
authors.lastname: Someya
authors.forename: Ryoko
authors.initials: R
authors.lastname: Fukushima
authors.forename: Michiko
authors.initials: M
authors.lastname: Yoshida
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Tanahashi
authors.forename: Tangmunkhong
authors.initials: T
authors.lastname: Prapeuk
authors.forename: Reiko
authors.initials: R
authors.lastname: Iizuka
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hirami
authors.forename: Atsushi
authors.initials: A
authors.lastname: Matsuda
authors.forename: Shunichi
authors.initials: S
authors.lastname: Takahashi
authors.forename: Goro
authors.initials: G
authors.lastname: Kurita
authors.forename: Takashi
authors.initials: T
authors.lastname: Kimura
authors.forename: Misuzu
authors.initials: M
authors.lastname: Seo
authors.forename: Masayuki
authors.initials: M
authors.lastname: Funaba
authors.forename: Yoshii
authors.initials: Y
authors.lastname: Nishino
mesh_terms: D000367:Age Factors; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D001890:Borna Disease / Q000453:epidemiology* / Q000635:transmission*; D001891:Borna disease virus / Q000276:immunology*; D002371:Cat Diseases / Q000453:epidemiology* / Q000635:transmission* / Q000821:virology*; D002415:Cats; D018445:Infectious Disease Transmission, Vertical / Q000662:veterinary*; D007564:Japan / Q000453:epidemiology; D015995:Prevalence; D012621:Seasons
chemical_list: D000914:Antibodies, Viral