title: Mass spectrometry in environmental toxicology.
abstract: In environmental toxicology, mass spectrometry can be applied to evaluate both exposure to chemicals as well as their effects in organisms. Various ultra-trace techniques are employed today to measure pollutants in different environmental compartments. Increasingly, effect-directed analysis is being applied to focus chemical monitoring on sites of ecotoxicological concern. Mass spectrometry is also very instrumental for studying the interactions of chemicals with organisms on the molecular and cellular level, providing new insights into mechanisms of toxicity. In the future, diverse mass spectrometry-based techniques are expected to become even more widely used in this field, contributing to the refinement of currently used environmental risk assessment strategies.
authors.affiliation: Department of Environmental Toxicology, Eawag - Swiss Federal Institute of Aquatic Science and Technology, Ueberlandstrasse 133, CH-8600 Dübendorf; ETH Zürich, Switzerland; Department of Chemistry and Applied Biosciences, CH-8093 Zürich, Switzerland.
authors.forename: Ksenia J
authors.initials: KJ
authors.lastname: Groh
authors.affiliation: Department of Environmental Toxicology, Eawag - Swiss Federal Institute of Aquatic Science and Technology, Ueberlandstrasse 133, CH-8600 Dübendorf, Switzerland; ETH Zürich, Institute of Biogeochemistry and Pollutant Dynamics, CH-8092 Zürich, Switzerland.
authors.forename: Marc J-F
authors.initials: MJ
authors.lastname: Suter
mesh_terms: D000818:Animals; D059001:Aquatic Organisms / Q000187:drug effects / Q000378:metabolism; D054750:Ecotoxicology / Q000295:instrumentation / Q000379:methods* / Q000639:trends; D004785:Environmental Pollutants / Q000737:chemistry* / Q000633:toxicity*; D013058:Mass Spectrometry / Q000295:instrumentation / Q000379:methods*; D040901:Proteomics / Q000295:instrumentation / Q000379:methods*
chemical_list: D004785:Environmental Pollutants