title: Association between Urinary Bisphenol A and Waist Circumference in Korean Adults.
abstract: Bisphenol A (BPA) is widely used in the production of polycarbonate plastics, epoxy resins, and food and beverage containers. In the present study, we aimed to investigate the relationship between urinary concentrations of BPA and waist circumference in Korean adults. A total of 1,030 Korean adults (mean age, 44.3 ± 14.6 years) were enrolled in the study on the integrated exposure to hazardous materials for safety control, conducted by the Ministry of Food and Drug Safety from 2010 to 2012. Abdominal obesity was defined as having a waist circumference of at least 90 cm and 85 cm for men and women, respectively. The participants were divided into 4 groups according to the urinary BPA concentration quartile. Waist circumference was significantly higher among subjects with a urinary BPA concentration in the highest quartile relative to those in the lowest quartile (p = 0.0071). Linear regression analysis revealed a significant positive association between urinary BPA concentrations and body mass index, body fat, after adjusting for potential confounders. Moreover, subjects with urinary BPA concentrations in the fourth quartile were more likely to be obese compared to those with urinary BPA concentrations in the first quartile (odds ratio, 1.938; 95% CI: 1.314~2.857; p for trend = 0.0106). These findings provide evidence for a positive association between urinary BPA concentration and waist circumference in Korean adults.
authors.affiliation: Food Safety Risk Assessment Division, National Institute of Food and Drug Safety Evaluation, Chungcheongbuk-do, Korea.
authors.forename: Ahra
authors.initials: A
authors.lastname: Ko
authors.affiliation: Food Safety Risk Assessment Division, National Institute of Food and Drug Safety Evaluation, Chungcheongbuk-do, Korea.
authors.forename: Myung-Sil
authors.initials: MS
authors.lastname: Hwang
authors.affiliation: Food Safety Risk Assessment Division, National Institute of Food and Drug Safety Evaluation, Chungcheongbuk-do, Korea.
authors.forename: Jae-Hong
authors.initials: JH
authors.lastname: Park
authors.affiliation: Food Safety Risk Assessment Division, National Institute of Food and Drug Safety Evaluation, Chungcheongbuk-do, Korea.
authors.forename: Hui-Seung
authors.initials: HS
authors.lastname: Kang
authors.affiliation: Food Safety Risk Assessment Division, National Institute of Food and Drug Safety Evaluation, Chungcheongbuk-do, Korea.
authors.forename: Hee-Seok
authors.initials: HS
authors.lastname: Lee
authors.affiliation: Food Safety Risk Assessment Division, National Institute of Food and Drug Safety Evaluation, Chungcheongbuk-do, Korea.
authors.forename: Jin-Hwan
authors.initials: JH
authors.lastname: Hong
keywords: Bisphenol A; Korean adults; Waist circumference