title: Genotyping of immune-related genetic variants identifies TYK2 as a novel associated locus for idiopathic inflammatory myopathies.
authors.affiliation: Arthritis Research UK Centre for Epidemiology, Musculoskeletal Research Group, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
authors.forename: M
authors.initials: M
authors.lastname: Jani
authors.affiliation: Arthritis Research UK Centre for Epidemiology, Musculoskeletal Research Group, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK The Dermatology Centre, Salford Royal NHS Foundation Trust, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
authors.forename: J
authors.initials: J
authors.lastname: Massey
authors.affiliation: Rheumatology Unit, Institute of Child Health, University College London, London, UK.
authors.forename: L R
authors.initials: LR
authors.lastname: Wedderburn
authors.affiliation: Institute of Rheumatology, Charles University in Prague, Prague, Czech Republic.
authors.forename: J
authors.initials: J
authors.lastname: Vencovský
authors.affiliation: University of Debrecen, Debrecen, Hungary.
authors.forename: K
authors.initials: K
authors.lastname: Danko
authors.affiliation: Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden.
authors.forename: I E
authors.initials: IE
authors.lastname: Lundberg
authors.affiliation: Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden.
authors.forename: L
authors.initials: L
authors.lastname: Padyukov
authors.affiliation: Vall d'Hebron General Hospital, Barcelona, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Selva-O'Callaghan
authors.affiliation: Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
authors.forename: T
authors.initials: T
authors.lastname: Radstake
authors.affiliation: Centre for Integrated Genomic Medical Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
authors.forename: H
authors.initials: H
authors.lastname: Platt
authors.affiliation: The Dermatology Centre, Salford Royal NHS Foundation Trust, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
authors.forename: R B
authors.initials: RB
authors.lastname: Warren
authors.affiliation: The Dermatology Centre, Salford Royal NHS Foundation Trust, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
authors.forename: C E
authors.initials: CE
authors.lastname: Griffiths
authors.affiliation: Feinstein Institute for Medical Research, Manhasset, New York, USA.
authors.forename: A
authors.initials: A
authors.lastname: Lee
authors.affiliation: Feinstein Institute for Medical Research, Manhasset, New York, USA.
authors.forename: P K
authors.initials: PK
authors.lastname: Gregersen
authors.affiliation: National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: F W
authors.initials: FW
authors.lastname: Miller
authors.affiliation: Centre for Integrated Genomic Medical Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
authors.forename: W E
authors.initials: WE
authors.lastname: Ollier
authors.affiliation: Department of Musculoskeletal Biology, University of Liverpool, Liverpool, UK.
authors.forename: R G
authors.initials: RG
authors.lastname: Cooper
authors.affiliation: Arthritis Research UK Centre for Epidemiology, Musculoskeletal Research Group, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK Centre for Integrated Genomic Medical Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
authors.forename: H
authors.initials: H
authors.lastname: Chinoy
authors.affiliation: Centre for Integrated Genomic Medical Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
authors.forename: J A
authors.initials: JA
authors.lastname: Lamb
mesh_terms: D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D009220:Myositis / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide; D017285:Polymyositis / Q000235:genetics; D053634:TYK2 Kinase / Q000235:genetics*
chemical_list: D053634:TYK2 Kinase; C070139:TYK2 protein, human
keywords: Autoimmunity; Dermatomyositis; Gene Polymorphism; Polymyositis