title: Total synthesis of biselyngbyolide A.
abstract: Biselyngbyolide A is an 18-membered macrolide that exhibits significant biological activities such as growth-inhibitory activity and apoptosis inducing activity against cancer cells. In this study, the first total synthesis of biselyngbyolide A by using an intramolecular Stille coupling reaction as a key step is achieved.
authors.affiliation: Department of Chemistry, Faculty of Science and Technology, Keio University , Hiyoshi 3-14-1, Kohoku-ku, Yokohama 223-8522, Japan.
authors.forename: Yurika
authors.initials: Y
authors.lastname: Tanabe
authors.forename: Eisuke
authors.initials: E
authors.lastname: Sato
authors.forename: Naoya
authors.initials: N
authors.lastname: Nakajima
authors.forename: Akifumi
authors.initials: A
authors.lastname: Ohkubo
authors.forename: Osamu
authors.initials: O
authors.lastname: Ohno
authors.forename: Kiyotake
authors.initials: K
authors.lastname: Suenaga
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D002460:Cell Line; D020128:Inhibitory Concentration 50; D018942:Macrolides / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure
chemical_list: D000970:Antineoplastic Agents; D018942:Macrolides; C000591954:biselyngbyolide A