title: Effusion cytology: an effective method for the diagnosis of pulmonary lymphangioleiomyomatosis.
abstract: Lymphangioleiomyomatosis (LAM) is a rare progressive lung disease. Chylous effusion is one of the most common clinical manifestations of LAM. Herein we present a 39-year-old female who presented progressive dyspnea on exertion and chylothorax. The chest computed tomography showed multiple thin-walled cysts in both lungs which suggesting LAM. The pleural effusion cytology plus with further immunocytochemistry confirmed the computed tomography diagnosis. Therefore, the LAM can be diagnosed by cytologic examination combined with conventional chest computed tomography and clinical manifestations, which can help some patients to avoid an invasive biopsy.
authors.affiliation: 1 Department of Pathology, 2 Department of Prevention Care, the Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China.
authors.forename: Daming
authors.initials: D
authors.lastname: Fan
authors.affiliation: 1 Department of Pathology, 2 Department of Prevention Care, the Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China.
authors.forename: Li
authors.initials: L
authors.lastname: Ding
authors.affiliation: 1 Department of Pathology, 2 Department of Prevention Care, the Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Liu
authors.affiliation: 1 Department of Pathology, 2 Department of Prevention Care, the Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China.
authors.forename: Jigang
authors.initials: J
authors.lastname: Wang
authors.affiliation: 1 Department of Pathology, 2 Department of Prevention Care, the Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China.
authors.forename: Wenwen
authors.initials: W
authors.lastname: Ran
authors.affiliation: 1 Department of Pathology, 2 Department of Prevention Care, the Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China.
authors.forename: Yujun
authors.initials: Y
authors.lastname: Li
authors.affiliation: 1 Department of Pathology, 2 Department of Prevention Care, the Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China.
authors.forename: Dongliang
authors.initials: D
authors.lastname: Lin
keywords: Lymphangioleiomyomatosis (LAM); cytology; diagnosis; immunocytochemistry