title: Semilunar valve replacement with decellularized homograft after Damus-Kaye-Stansel anastomosis and fontan procedure.
abstract: We describe a patient in whom severe neoaortic (anatomic pulmonary) valve regurgitation developed late after Damus-Kaye-Stansel anastomosis and Fontan operation. The valve was replaced with a fresh decellularized homograft, which we developed and applied in the normal pulmonary and aortic position in more than 100 patients. During follow-up of more than 2 years, the valve function is excellent, and no infectious or thromboembolic complications were seen. The decellularized homograft seems to be an ideal material in this situation.
authors.affiliation: Division of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School, Hannover, Germany. Electronic address: bobylev.dmitry@mh-hannover.de.
authors.forename: Dmitry
authors.initials: D
authors.lastname: Bobylev
authors.affiliation: Division of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School, Hannover, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Breymann
authors.affiliation: Division of Pediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.
authors.forename: Dietmar
authors.initials: D
authors.lastname: Boethig
authors.affiliation: Division of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School, Hannover, Germany.
authors.forename: Axel
authors.initials: A
authors.lastname: Haverich
authors.affiliation: Division of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School, Hannover, Germany.
authors.forename: Masamichi
authors.initials: M
authors.lastname: Ono
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000601:surgery; D062088:Acellular Dermis; D000714:Anastomosis, Surgical / Q000009:adverse effects / Q000379:methods; D000792:Angiography / Q000379:methods; D001017:Aortic Coarctation / Q000175:diagnosis / Q000601:surgery; D058385:Cardiac Valve Annuloplasty / Q000379:methods*; D018376:Cardiovascular Abnormalities / Q000175:diagnosis* / Q000601:surgery*; D002648:Child; D004310:Double Outlet Right Ventricle / Q000175:diagnosis / Q000601:surgery; D015150:Echocardiography, Doppler / Q000379:methods; D005500:Follow-Up Studies; D018729:Fontan Procedure / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000175:diagnosis / Q000601:surgery; D011665:Pulmonary Valve Insufficiency / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D018570:Risk Assessment; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods; D014184:Transplantation, Homologous; D014188:Transposition of Great Vessels / Q000175:diagnosis / Q000601:surgery; D016896:Treatment Outcome