title: Non-O1, non-O139 Vibrio cholerae bacteraemia in an Australian population.
abstract: This retrospective case series identifies the largest cohort of non-O1, non-O139 Vibrio cholerae bacteraemia in an Australian population from 2000 to 2013. We examine the risk factors, epidemiology, clinical presentations and mortality of non-O1, non-O139 V. cholerae bacteraemia in Victoria and compare them with published cases in the literature. This case series highlights the pathogenic potential of non-O1, non-O139 V. cholerae and identifies possible associations with host (underlying chronic liver disease and malignancy) and environmental factors (contaminated water supply and raw seafood). Clinicians should be aware of the morbidity and mortality associated with invasive non-O1, non-O139 V. cholerae infections, particularly in immunocompromised patients.
authors.affiliation: Department of Infectious Diseases, Austin Health, Melbourne, Victoria, Australia; Communicable Disease Prevention and Control Section, Health Protection Branch, Victorian Government Department of Health, Melbourne, Victoria, Australia.
authors.forename: J A
authors.initials: JA
authors.lastname: Trubiano
authors.forename: J Y H
authors.initials: JY
authors.lastname: Lee
authors.forename: M
authors.initials: M
authors.lastname: Valcanis
authors.forename: J
authors.initials: J
authors.lastname: Gregory
authors.forename: B A
authors.initials: BA
authors.lastname: Sutton
authors.forename: N E
authors.initials: NE
authors.lastname: Holmes
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D016470:Bacteremia / Q000453:epidemiology / Q000382:microbiology*; D015897:Comorbidity; D003296:Cooking; D004198:Disease Susceptibility; D005260:Female; D005516:Food Microbiology; D005759:Gastroenteritis / Q000150:complications / Q000453:epidemiology / Q000382:microbiology; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D010125:Ostreidae / Q000382:microbiology; D012189:Retrospective Studies; D012307:Risk Factors; D017747:Seafood / Q000009:adverse effects / Q000382:microbiology; D012703:Serotyping; D013550:Swimming; D044163:Vibrio cholerae non-O1 / Q000145:classification / Q000302:isolation & purification*; D014739:Victoria / Q000453:epidemiology; D014871:Water Microbiology; D014876:Water Pollution
keywords: Vibrio cholerae; bacteraemia; non-O1; non-O139.; non-toxigenic