title: Adrenal insufficiency during treatment for childhood acute lymphoblastic leukemia is associated with glucocorticoid receptor polymorphisms ER22/23EK and BclI.
authors.affiliation: Department of Pediatrics, Division Oncology/Hematology, VU University Medical Center, Amsterdam, the Netherlands.
authors.forename: Ruben D
authors.initials: RD
authors.lastname: de Ruiter
authors.affiliation: Department of Pediatrics, Division Oncology/Hematology, VU University Medical Center, Amsterdam, the Netherlands ms.gordijn@vumc.nl.
authors.forename: M Suzanne
authors.initials: MS
authors.lastname: Gordijn
authors.affiliation: Department of Pediatrics, Division of General Pediatrics and other subspecialties, VU University Medical Center, Amsterdam, the Netherlands.
authors.forename: Reinoud J B J
authors.initials: RJ
authors.lastname: Gemke
authors.affiliation: Department of Pediatric Oncology, Emma Children's Hospital/Academic Medical Center, Amsterdam, the Netherlands.
authors.forename: Cor
authors.initials: C
authors.lastname: van den Bos
authors.affiliation: Department of Pediatric Hemato/Oncology, University Medical Center Utrecht, Amsterdam, the Netherlands.
authors.forename: Marc B
authors.initials: MB
authors.lastname: Bierings
authors.affiliation: Department of Pediatrics, Division of Endocrinology, VU University Medical Center, Amsterdam, the Netherlands.
authors.forename: Joost
authors.initials: J
authors.lastname: Rotteveel
authors.affiliation: Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.
authors.forename: Jan W
authors.initials: JW
authors.lastname: Koper
authors.affiliation: Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.
authors.forename: Elisabeth F C
authors.initials: EF
authors.lastname: van Rossum
authors.affiliation: Department of Pediatrics, Division Oncology/Hematology, VU University Medical Center, Amsterdam, the Netherlands.
authors.forename: Gertjan L
authors.initials: GL
authors.lastname: Kaspers
mesh_terms: D000293:Adolescent; D000309:Adrenal Insufficiency / Q000139:chemically induced / Q000175:diagnosis* / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D010865:Pilot Projects; D011110:Polymorphism, Genetic / Q000235:genetics*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics*; D011241:Prednisone / Q000009:adverse effects; D011965:Receptors, Glucocorticoid / Q000235:genetics*; D016896:Treatment Outcome
chemical_list: D011965:Receptors, Glucocorticoid; D011241:Prednisone
keywords: ALL; GR polymorphisms; adrenal insufficiency; childhood