title: Tai Chi exercise increases SOD activity and total antioxidant status in saliva and is linked to an improvement of periodontal disease in the elderly.
abstract: The aim of this study was to determine the effect of Tai Chi on biological markers of oxidative stress in saliva and its relationship with periodontal disease (PD) in older adults. We carried out a quasi-experimental study with a sample of 71 sedentary volunteers with PD who were divided into a control group of 34 subjects and an experimental group of 37 subjects who performed Tai Chi 5 days a week for a period of 6 months. PD status was characterized using the Periodontal Disease Index (PDI). Superoxide dismutase (SOD), total antioxidant status (TAS), and TBARS levels of both groups were measured by spectrophotometric methods. In addition, inflammation markers (TNF-α, IL-1β, IL-6, IL-8, and IL-10) were measured by flow cytometry. We found a statistically significant increase in SOD activity (P < 0.001) and TAS concentration (P < 0.05), whereas levels of IL-1β were significantly lower (P < 0.01). Likewise, a statistically significant decrease in the PDI (P < 0.05) was observed in subjects who performed Tai Chi during a period of 6 months. Our findings suggest that the practice of Tai Chi has both antioxidant and anti-inflammatory effects that are linked to the improvement of PD in older adults.
authors.affiliation: Unidad de Investigación en Gerontología, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México (UNAM), Guelatao No. 66, Delegación Iztapalapa, 09230 México, DF, Mexico.
authors.forename: Víctor Manuel
authors.identifier: 0000-0002-9137-3405
authors.initials: VM
authors.lastname: Mendoza-Núñez
authors.affiliation: Unidad de Investigación en Gerontología, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México (UNAM), Guelatao No. 66, Delegación Iztapalapa, 09230 México, DF, Mexico.
authors.forename: Beatriz
authors.initials: B
authors.lastname: Hernández-Monjaraz
authors.affiliation: Laboratorio de Biología Celular y Molecular del Cáncer, UIDCC, FES-Zaragoza, UNAM, México, DF, Mexico.
authors.forename: Edelmiro
authors.initials: E
authors.lastname: Santiago-Osorio
authors.affiliation: Departamento de Ciencias de la Salud, Universidad Autónoma Metropolitana-Iztapalapa, Apartado Postal 55-535, 09340 México, DF, Mexico.
authors.forename: José Miguel
authors.initials: JM
authors.lastname: Betancourt-Rule
authors.affiliation: Unidad de Investigación en Gerontología, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México (UNAM), Guelatao No. 66, Delegación Iztapalapa, 09230 México, DF, Mexico.
authors.forename: Mirna
authors.initials: M
authors.lastname: Ruiz-Ramos
mesh_terms: D000368:Aged; D000975:Antioxidants / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D008054:Lipid Peroxides / Q000378:metabolism; D008875:Middle Aged; D018384:Oxidative Stress; D010510:Periodontal Diseases / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control*; D012463:Saliva / Q000378:metabolism*; D013053:Spectrophotometry; D013482:Superoxide Dismutase / Q000378:metabolism*; D026302:Tai Ji
chemical_list: D000975:Antioxidants; D008054:Lipid Peroxides; D013482:Superoxide Dismutase