title: Acquired bilateral telangiectatic macules: a distinct clinical entity.
abstract: OBJECTIVE
  We evaluated 13 distinct patients with multiple telangiectatic pigmented macules confined mostly to the upper arms to determine if the clinical and histopathological features of these cases might represent a specific clinical entity.
  
  
  METHODS
  We retrospectively investigated the clinical, histopathologic, and immunohistochemical features of 13 patients with multiple telangiectatic pigmented macules on the upper arms who presented between January 2003 and December 2012. Epidermal pigmentation, melanogenic activity, melanocyte number, vascularity, epidermal thickness, and perivascular mast cell number of the specimens were evaluated. Clinically, the condition favored middle-aged men. On histopathologic examination, the lesional skin showed capillary proliferation and telangiectasia in the upper dermis. Histochemical and immunohistochemical analysis revealed basal hyperpigmentation and increased melanogenic activity in the lesional skin (P < .05). No significant difference in epidermal thickness or mast cell number was observed between the normal perilesional skin and the lesional skin.
  
  
  CONCLUSIONS
  The clinical and histopathologic features of these lesions were relatively consistent in all patients. In addition, the features are quite distinct from other diseases. Based on clinical and histologic features, we suggest the name acquired bilateral telangiectatic macules for this new entity.
authors.affiliation: Department of Dermatology, Ajou University School of Medicine, Suwon, South Korea.
authors.forename: Ji-Hye
authors.initials: JH
authors.lastname: Park
authors.affiliation: Department of Dermatology, Ajou University School of Medicine, Suwon, South Korea.
authors.forename: Dong Jun
authors.initials: DJ
authors.lastname: Lee
authors.affiliation: Ajou University School of Medicine, Suwon, South Korea.
authors.forename: Yoo-Jung
authors.initials: YJ
authors.lastname: Lee
authors.affiliation: Department of Dermatology, Kyungpook National University School of Medicine, Daegu, South Korea.
authors.forename: Yong Hyun
authors.initials: YH
authors.lastname: Jang
authors.affiliation: Department of Dermatology, Ajou University School of Medicine, Suwon, South Korea.
authors.forename: Hee Young
authors.initials: HY
authors.lastname: Kang
authors.affiliation: Department of Dermatology, Ajou University School of Medicine, Suwon, South Korea.
authors.forename: You Chan
authors.initials: YC
authors.lastname: Kim
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D017445:Skin Diseases, Vascular / Q000473:pathology*; D013684:Telangiectasis / Q000473:pathology*