title: ¹⁸F-FDG PET/CT imaging for a gastrointestinal mantle cell lymphoma with multiple lymphomatous polyposis.
abstract: Multiple lymphomatous polyposis (MLP) is an uncommon type of gastrointestinal lymphoma characterized by the presence of multiple polyps along the gastrointestinal tract. Most of this entity is in fact considered the counterpart of gastrointestinal tract involvement for mantle cell lymphoma (MCL). To our knowledge, there have been no reports on [fluorine-18]-fluorodeoxy-glucose ((18)F-FDG)-positron emission tomography (PET)/computed tomography (CT) imaging for gastrointestinal MCL with MLP. We present the results of (18)F-FDG PET/CT imaging in a patient with gastrointestinal tract involvement of MCL showing continuous MLP from the stomach to the rectum and intestinal intussusception. FDG-PET/CT findings were false negative in typical MLP spreading widely over the gastrointestinal tract, but uptake was noted in large lesions with deep infiltration considered atypical as MLP. On FDG-PET/CT imaging, the Ki-67 proliferative index, which is a cell proliferation marker, showed neither correlation with the presence of uptake nor the maximum standardized uptake value.
authors.affiliation: Makoto Saito, Koh Izumiyama, Akio Mori, Tatsuro Irie, Masanori Tanaka, Masanobu Morioka, Department of Internal Medicine and Hematology, Aiiku Hospital, Sapporo 064-0804, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Saito
authors.affiliation: Makoto Saito, Koh Izumiyama, Akio Mori, Tatsuro Irie, Masanori Tanaka, Masanobu Morioka, Department of Internal Medicine and Hematology, Aiiku Hospital, Sapporo 064-0804, Japan.
authors.forename: Masaya
authors.initials: M
authors.lastname: Miyazaki
authors.affiliation: Makoto Saito, Koh Izumiyama, Akio Mori, Tatsuro Irie, Masanori Tanaka, Masanobu Morioka, Department of Internal Medicine and Hematology, Aiiku Hospital, Sapporo 064-0804, Japan.
authors.forename: Mishie
authors.initials: M
authors.lastname: Tanino
authors.affiliation: Makoto Saito, Koh Izumiyama, Akio Mori, Tatsuro Irie, Masanori Tanaka, Masanobu Morioka, Department of Internal Medicine and Hematology, Aiiku Hospital, Sapporo 064-0804, Japan.
authors.forename: Shinya
authors.initials: S
authors.lastname: Tanaka
authors.affiliation: Makoto Saito, Koh Izumiyama, Akio Mori, Tatsuro Irie, Masanori Tanaka, Masanobu Morioka, Department of Internal Medicine and Hematology, Aiiku Hospital, Sapporo 064-0804, Japan.
authors.forename: Kencho
authors.initials: K
authors.lastname: Miyashita
authors.affiliation: Makoto Saito, Koh Izumiyama, Akio Mori, Tatsuro Irie, Masanori Tanaka, Masanobu Morioka, Department of Internal Medicine and Hematology, Aiiku Hospital, Sapporo 064-0804, Japan.
authors.forename: Koh
authors.initials: K
authors.lastname: Izumiyama
authors.affiliation: Makoto Saito, Koh Izumiyama, Akio Mori, Tatsuro Irie, Masanori Tanaka, Masanobu Morioka, Department of Internal Medicine and Hematology, Aiiku Hospital, Sapporo 064-0804, Japan.
authors.forename: Akio
authors.initials: A
authors.lastname: Mori
authors.affiliation: Makoto Saito, Koh Izumiyama, Akio Mori, Tatsuro Irie, Masanori Tanaka, Masanobu Morioka, Department of Internal Medicine and Hematology, Aiiku Hospital, Sapporo 064-0804, Japan.
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Irie
authors.affiliation: Makoto Saito, Koh Izumiyama, Akio Mori, Tatsuro Irie, Masanori Tanaka, Masanobu Morioka, Department of Internal Medicine and Hematology, Aiiku Hospital, Sapporo 064-0804, Japan.
authors.forename: Masanori
authors.initials: M
authors.lastname: Tanaka
authors.affiliation: Makoto Saito, Koh Izumiyama, Akio Mori, Tatsuro Irie, Masanori Tanaka, Masanobu Morioka, Department of Internal Medicine and Hematology, Aiiku Hospital, Sapporo 064-0804, Japan.
authors.forename: Masanobu
authors.initials: M
authors.lastname: Morioka
authors.affiliation: Makoto Saito, Koh Izumiyama, Akio Mori, Tatsuro Irie, Masanori Tanaka, Masanobu Morioka, Department of Internal Medicine and Hematology, Aiiku Hospital, Sapporo 064-0804, Japan.
authors.forename: Eriko
authors.initials: E
authors.lastname: Tsukamoto
mesh_terms: D018256:Adenomatous Polyps / Q000737:chemistry / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy; D049109:Cell Proliferation; D016099:Endoscopy, Gastrointestinal; D005260:Female; D019788:Fluorodeoxyglucose F18; D005770:Gastrointestinal Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy; D006801:Humans; D044483:Intestinal Polyposis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism / Q000628:therapy; D019394:Ki-67 Antigen / Q000032:analysis; D020522:Lymphoma, Mantle-Cell / Q000737:chemistry / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy; D008875:Middle Aged; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D019275:Radiopharmaceuticals; D013274:Stomach Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy; D014057:Tomography, X-Ray Computed
chemical_list: D019394:Ki-67 Antigen; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: 18F-fluorodeoxy-glucose-positron emission tomography/computed tomography imaging; Gastrointestinal tract; Ki-67 proliferative index; Mantle cell lymphoma; Multiple lymphomatous polyposis