title: Improving osseointegration of Co-Cr by nanostructured titanium coatings.
abstract: This study reports the deposition of nanostructured Ti films on Co-Cr substrates to improve their surface characteristics and biocompatibility. The microstructure of the Ti films was controlled by application of negative substrate bias voltages. The surface roughness of Co-Cr implants was increased significantly after Ti coatings. The nanostructured Ti films are found to improve osteointergration of Co-Cr implants as indicated by enhancing cellular attachment, proliferation and differentiation, which was attributed mainly to the application of a biocompatible Ti coating, possessed a higher surface area for cell attachments and growth.
authors.affiliation: Advanced Institute for Science and Technology (AIST), Hanoi University of Science and Technology (HUST), No 01, Dai Co Viet road, Hanoi, Vietnam.
authors.forename: Vuong-Hung
authors.initials: VH
authors.lastname: Pham
keywords: Alloys; Biomaterials; Coatings; Metal; Sputtering; Thin films