title: Emerging therapeutic options for eosinophilic esophagitis.
abstract: Eosinophilic esophagitis (EoE) is a chronic inflammatory condition of the esophagus that often occurs in atopic persons. Management strategies include pharmacotherapy, dietary modification, and endoscopic therapy, although patients will often have a relapsing and remitting course. Currently, the primary pharmacotherapy for EoE consists of corticosteroids. Immuno-modulators, leukotriene antagonists, biologies, and monoclonal antibodies are currently under study for treatment of EoE. The role of immunoglobulin E-mediated allergic reactions has been well documented and may provide insight into the etiology and effective therapy of EoE.
authors.affiliation: Dr Dougherty is a fellow and Dr Borum is a professor of medicine and chair in the Division of Gastroenterology and Liver Diseases at The George Washington University in Washington, DC. Both doctors are also affiliated with The George Washington University Medical Faculty Associates. Dr Stephen is an office-based gastroenterologist in Silver Spring, Maryland. Dr Doman is a clinical professor of medicine at The George Washington University.
authors.forename: Timothy
authors.initials: T
authors.lastname: Dougherty
authors.affiliation: Dr Dougherty is a fellow and Dr Borum is a professor of medicine and chair in the Division of Gastroenterology and Liver Diseases at The George Washington University in Washington, DC. Both doctors are also affiliated with The George Washington University Medical Faculty Associates. Dr Stephen is an office-based gastroenterologist in Silver Spring, Maryland. Dr Doman is a clinical professor of medicine at The George Washington University.
authors.forename: Sindu
authors.initials: S
authors.lastname: Stephen
authors.affiliation: Dr Dougherty is a fellow and Dr Borum is a professor of medicine and chair in the Division of Gastroenterology and Liver Diseases at The George Washington University in Washington, DC. Both doctors are also affiliated with The George Washington University Medical Faculty Associates. Dr Stephen is an office-based gastroenterologist in Silver Spring, Maryland. Dr Doman is a clinical professor of medicine at The George Washington University.
authors.forename: Marie L
authors.initials: ML
authors.lastname: Borum
authors.affiliation: Dr Dougherty is a fellow and Dr Borum is a professor of medicine and chair in the Division of Gastroenterology and Liver Diseases at The George Washington University in Washington, DC. Both doctors are also affiliated with The George Washington University Medical Faculty Associates. Dr Stephen is an office-based gastroenterologist in Silver Spring, Maryland. Dr Doman is a clinical professor of medicine at The George Washington University.
authors.forename: David B
authors.initials: DB
authors.lastname: Doman
keywords: Eosinophilic esophagitis; proton pump inhibitor—responsive esophageal eosinophilia; reflux esophagitis