title: Dietary exposure and risk assessment to lead of the population of Jiangsu province, China.
abstract: The paper's main purpose is to estimate the dietary exposure to lead for the inhabitants of Jiangsu province, China. Lead concentration data were obtained from the national food contamination monitoring programme during 2007-10. Food samples (n = 2077) were collected from 23 food categories in Jiangsu province. Consumption data were derived from Chinese national nutrition and health survey in 2002, which included 3938 inhabitants from 1451 households in Jiangsu province. Concentration data were combined with consumption data to estimate the dietary intake for the inhabitants of 2-6, 7-17 and 18-80 years, respectively. The β-binomial-normal (BBN) model was used to estimate the long-term intake for the population in Jiangsu province. The distribution of individual margin of exposure (IMoE) was introduced to assess the health effect. Uncertainty of IMoE was quantified by Monte Carlo and bootstrap methods. The mean levels of dietary exposure to lead were estimated at 3.019 µg kg(-1) bw day(-1) for children aged 2-6 years, 2.104 µg kg(-1) bw day(-1) for teenagers aged 7-17 years, and 1.601 µg kg(-1) bw day(-1) for adults aged 18-80 years. The mean intakes for the urban and rural populations were 1.494 and 1.822 µg kg(-1) bw day(-1), respectively. From the 25th to 99.9th percentiles, IMoE was 0.125-2.057 for 2-6 years and 0.473-7.998 for 18-80 years, respectively. The distribution of IMoE could indicate a public health concern on lead for the Chinese population in Jiangsu. Control measures should be taken to reduce lead exposure in Jiangsu province.
authors.affiliation: a Department of Epidemiology and Biostatistics, School of Public Health , Southeast University , Nanjing , China.
authors.forename: Yingliang
authors.initials: Y
authors.lastname: Jin
authors.forename: Pei
authors.initials: P
authors.lastname: Liu
authors.forename: Jinfang
authors.initials: J
authors.lastname: Sun
authors.forename: Cannan
authors.initials: C
authors.lastname: Wang
authors.forename: Jie
authors.initials: J
authors.lastname: Min
authors.forename: Yafei
authors.initials: Y
authors.lastname: Zhang
authors.forename: Shiyuan
authors.initials: S
authors.lastname: Wang
authors.forename: Yongning
authors.initials: Y
authors.lastname: Wu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D002681:China; D004435:Eating; D004781:Environmental Exposure / Q000032:analysis; D005260:Female; D005506:Food Contamination / Q000032:analysis* / Q000706:statistics & numerical data; D006801:Humans; D007854:Lead / Q000008:administration & dosage / Q000032:analysis* / Q000633:toxicity; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D018570:Risk Assessment / Q000706:statistics & numerical data; D055815:Young Adult
chemical_list: D007854:Lead
keywords: dietary exposure; individual margin of exposure; lead; uncertainty analysis