title: Placement of hemoparin-coated stents in the iliac arteries: early experience and midterm results in 28 patients.
abstract: OBJECTIVE
  Aim was to determine immediate results and mid-term outcome of the hemoparin-coated (HC) stainless-steel stent (camouflage coating) in the treatment of occlusive lesions of the iliac arteries.
  
  
  METHODS
  Twenty-eight patients were prospectively treated with the use of a HC stent between January 2007 and March 2010. Clinical examination and color-doppler ultrasound were performed at 1, 3, 6 and 12 months, CT angiography (CTA) or MR angiography (MRA) at 12 months. Indication for treatment was a high-grade stenosis of the common iliac and/or external iliac artery.
  
  
  RESULTS
  Successful placement was achieved in all patients. Significant decrease in translesional pressure gradient (>10 mm Hg) was measured in 27 patients (96%). In one patient, proximal dissection occurred without flow limitation. A minor complication (small access site hematoma) occurred in one patient (4%). Two patients (7%) were lost to follow-up. After 12 months, stent patency in CTA, MRA and ultrasound was 100%. 20 patients (77%) experienced an initial improvement of at least one clinical stage. In one patient (4%), mild intimal hyperplasia without significant stenosis was observed. In three patients (12%), proximal or distal stenosis occurred. A non-significant increase of mean ankle-brachial index (ABI) after treatment was measured (0.85 ± 0.27 vs. 0.75 ± 0.22, respectively; p=0.328).
  
  
  CONCLUSIONS
  The use of HC stents in patients with iliac artery occlusive disease may lead to a lower rate of intimal hyperplasia and thus to increased patency rates even in heavily calcified vessels. However, large-scale prospective trials have to be performed to evaluate the long-term patency rates of the HC coated stents.
authors.affiliation: Medical University of Graz, Department of Radiology, Univ. Hospital Graz, Auenbruggerplatz 9, A-8036 Graz, Austria. Electronic address: peter.kalmar@medunigraz.at.
authors.forename: Peter I
authors.initials: PI
authors.lastname: Kalmar
authors.affiliation: Medical University of Graz, Department of Radiology, Univ. Hospital Graz, Auenbruggerplatz 9, A-8036 Graz, Austria. Electronic address: rupert.portugaller@medunigraz.at.
authors.forename: Rupert H
authors.initials: RH
authors.lastname: Portugaller
authors.affiliation: Medical University of Graz, Department of Radiology, Univ. Hospital Graz, Auenbruggerplatz 9, A-8036 Graz, Austria. Electronic address: peter.schedlbauer@klinikum-graz.at.
authors.forename: Peter
authors.initials: P
authors.lastname: Schedlbauer
authors.affiliation: Medical University of Graz, Department of Radiology, Univ. Hospital Graz, Auenbruggerplatz 9, A-8036 Graz, Austria. Electronic address: dennis.bohlsen@medunigraz.at.
authors.forename: Dennis
authors.initials: D
authors.lastname: Bohlsen
authors.affiliation: Medical University of Graz, Department of Radiology, Univ. Hospital Graz, Auenbruggerplatz 9, A-8036 Graz, Austria. Electronic address: hannes.deutschmann@medunigraz.at.
authors.forename: Hannes A
authors.initials: HA
authors.lastname: Deutschmann
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography / Q000379:methods; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D001807:Blood Vessel Prosthesis; D054855:Drug-Eluting Stents; D005260:Female; D006801:Humans; D007083:Iliac Artery / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D058729:Peripheral Arterial Disease / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D019919:Prosthesis Implantation / Q000379:methods*; D016896:Treatment Outcome
keywords: Angiography; Arterial intervention; Iliac artery; Intermittent claudication; Stents