title: Interaction of nanoparticles with lipid membranes: a multiscale perspective.
abstract: Freestanding lipid bilayers were challenged with 15 nm Au nanospheres either coated by a citrate layer or passivated by a protein corona. The effect of Au nanospheres on the bilayer morphology, permeability and fluidity presents strong differences or similarities, depending on the observation length scale, from the colloidal to the molecular domains. These findings suggest that the interaction between nanoparticles and lipid membranes should be conveniently treated as a multiscale phenomenon.
authors.affiliation: Department of Chemistry "Ugo Schiff" and CSGI, University of Florence, via della Lastruccia 3, 50019 Sesto Fiorentino, Florence, Italy. montis@csgi.unifi.it debora.berti@unifi.it.
authors.forename: Costanza
authors.initials: C
authors.lastname: Montis
authors.forename: Daniele
authors.initials: D
authors.lastname: Maiolo
authors.forename: Ivano
authors.initials: I
authors.lastname: Alessandri
authors.forename: Paolo
authors.initials: P
authors.lastname: Bergese
authors.forename: Debora
authors.initials: D
authors.lastname: Berti
mesh_terms: D004058:Diffusion; D006046:Gold / Q000737:chemistry*; D008051:Lipid Bilayers / Q000737:chemistry*; D008422:Materials Testing; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure*; D008956:Models, Chemical; D008958:Models, Molecular
chemical_list: D008051:Lipid Bilayers; D006046:Gold