title: Management of postoperative Crohn's disease.
abstract: Surgical treatment does not cure Crohn's disease, and postoperative recurrence is a feature of the clinical course of the disease. Ileocolonoscopy remains the gold standard for the surveillance of recurrent Crohn's disease and should be performed 6-12 months after an operation. Many other non-invasive techniques are also useful and complement endoscopy for the early diagnosis of postoperative recurrence. Anti-TNF agents show great efficacy for the prevention of postoperative recurrence, and long-term use can maintain remission. It remains undetermined whether early treatment after postoperative endoscopic recurrence is ultimately as efficacious as prophylactic therapy.
authors.affiliation: Xijing Hospital of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, 127 West Changle Road, Xi'an, China.
authors.forename: Zhiping
authors.initials: Z
authors.lastname: Yang
authors.forename: Qiong
authors.initials: Q
authors.lastname: Wu
authors.forename: Kaichun
authors.initials: K
authors.lastname: Wu
authors.forename: Daiming
authors.initials: D
authors.lastname: Fan
mesh_terms: D001688:Biological Products / Q000627:therapeutic use; D003113:Colonoscopy; D003424:Crohn Disease / Q000601:surgery*; D006801:Humans; D011183:Postoperative Complications / Q000175:diagnosis / Q000517:prevention & control* / Q000628:therapy*; D012008:Recurrence; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
chemical_list: D001688:Biological Products; D014409:Tumor Necrosis Factor-alpha
keywords: Crohn’s disease; anti-TNF agents; ileocolonoscopy; infliximab; non-invasive; postoperative recurrence; surgery; top-down