title: [Trichophyton rubrum onychomycosis with secondary Aspergillus versicolor infection in a 12-year-old girl: successful topical therapy with terbinafine-urea ointment].
abstract: METHODS
  A 12-year-old with a functional circulatory disturbance had toe nail onychomycosis caused by Trichophyton rubrum. There were no other underlying diseases.
  
  
  RESULTS
  Oral therapy with terbinafine 125 mg once weekly in addition to ciclopirox nail lacquer was ineffective. Two years later the disease worsened and A. versicolor was found in pure culture. A preparation of 10% terbinafine HCl in a 20% urea ointment (Onychomal®) applied daily for 4 weeks, then once weekly resulted in complete cure after 7 months.
authors.affiliation: Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Gießen und Marburg, Standort Gießen, Gaffkystr. 14, 35385, Gießen, Deutschland, Peter.Mayser@derma.med.uni-giessen.de.
authors.forename: P A
authors.initials: PA
authors.lastname: Mayser
authors.forename: A
authors.initials: A
authors.lastname: Gries
authors.forename: N
authors.initials: N
authors.lastname: Hamrouni
mesh_terms: D000287:Administration, Topical; D000935:Antifungal Agents / Q000008:administration & dosage; D001228:Aspergillosis / Q000188:drug therapy* / Q000473:pathology; D002648:Child; D004359:Drug Therapy, Combination / Q000379:methods; D005260:Female; D005533:Foot Dermatoses / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D009281:Naphthalenes / Q000008:administration & dosage*; D009824:Ointments / Q000008:administration & dosage; D014009:Onychomycosis / Q000188:drug therapy* / Q000473:pathology; D000077291:Terbinafine; D014005:Tinea / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome; D014508:Urea / Q000008:administration & dosage*
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D009824:Ointments; D014508:Urea; D000077291:Terbinafine