title: MicroRNA roles in the NF- κB signaling pathway during viral infections.
abstract: NF- κ B signaling network is a crucial component of innate immunity. miRNAs are a subtype of small noncoding RNAs, involved in regulation of gene expression at the posttranscriptional level. Increasing evidence has emerged that miRNAs play an important role in regulation of NF- κ B signaling pathway during viral infections. Both host and viral miRNAs are attributed to modulation of NF- κ B activity, thus affecting viral infection and clearance. Understandings of the mechanisms of these miRNAs will open a direction for development of novel antivirus drugs.
authors.affiliation: State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, CAAS, Lanzhou, Gansu 730046, China.
authors.forename: Zeqian
authors.identifier: 0000-0002-1792-116X
authors.initials: Z
authors.lastname: Gao
authors.affiliation: State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, CAAS, Lanzhou, Gansu 730046, China.
authors.forename: Yongxi
authors.initials: Y
authors.lastname: Dou
authors.affiliation: College of Life Science and Engineering, Northwest University for Nationalities, Lanzhou 730030, China.
authors.forename: Yixia
authors.initials: Y
authors.lastname: Chen
authors.affiliation: State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, CAAS, Lanzhou, Gansu 730046, China.
authors.forename: Yadong
authors.identifier: 0000-0001-6795-9978
authors.initials: Y
authors.lastname: Zheng
mesh_terms: D000818:Animals; D005786:Gene Expression Regulation / Q000235:genetics*; D006801:Humans; D035683:MicroRNAs / Q000235:genetics*; D008957:Models, Genetic; D016328:NF-kappa B / Q000235:genetics*; D015398:Signal Transduction / Q000235:genetics*; D014777:Virus Diseases / Q000235:genetics*
chemical_list: D035683:MicroRNAs; D016328:NF-kappa B