title: Live birth from a 46-year-old using fresh autologous oocytes through in vitro fertilization.
abstract: OBJECTIVE
  To report a live birth with IVF from a 46-year-old woman using autologous oocytes.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Reproductive endocrinology and infertility private practice and ambulatory IVF center.
  
  
  METHODS
  One 46-year-old nulligravid woman.
  
  
  METHODS
  IVF with fresh ET.
  
  
  METHODS
  Live birth after IVF.
  
  
  RESULTS
  A 46-year-old with antimullerian hormone (AMH) level less than 0.16 conceived through IVF using autologous oocytes. A total of seven oocytes were retrieved, from which four embryos were transferred at the cleavage stage, resulting in a pregnancy and delivery of a healthy male infant weighing 1,580 g at 31 and 3/7 weeks' estimated gestational age.
  
  
  CONCLUSIONS
  The prognosis for a live birth from IVF in a patient with very advanced reproductive age, particularly with an undetectable AMH level using autologous oocytes, remains extremely poor. This case should be interpreted with caution so as to not provide false hope to women aged 45 and above.
authors.affiliation: Fertility Center of Assisted Reproduction and Endocrinology, Winter Park, Florida. Electronic address: DrT@MyFertilityCARE.com.
authors.forename: Mark P
authors.initials: MP
authors.lastname: Trolice
mesh_terms: D000367:Age Factors; D054304:Anti-Mullerian Hormone / Q000097:blood; D015415:Biomarkers / Q000097:blood; D004624:Embryo Transfer; D005260:Female; D005298:Fertility; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000097:blood / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D050498:Live Birth; D008297:Male; D008875:Middle Aged; D054315:Oocyte Retrieval; D011247:Pregnancy; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D054304:Anti-Mullerian Hormone
keywords: Autologous oocytes; advanced reproductive age; antimullerian hormone; diminished ovarian reserve; in vitro fertilization