title: [Assessing drug targeting of Yougui Pill, Zuogui Pill, and their disassembled prescriptions using infrared thermography].
abstract: OBJECTIVE
  To dynamically assess drug targeting of Yougui Pill (YP) and Zuogui Pill (ZP) using infrared thermography.
  
  
  METHODS
  In this self-control experiment, five healthy volunteers were recruited. By using infrared thermography 10 to 11 thermal images of different body locations were taken from each participant after they took warm water, YP, ZP, and their dissembled prescriptions at 30, 70, 100, 130, and 160 min, respectively. The heat values in the lower quadrant abdomen, uterus, Du channel, and Shenque (CV8) were statistically analyzed after scanning for 125 times.
  
  
  RESULTS
  Administration of YP and its disassembled prescriptions enhanced the heat value of the locations of the Du channel and Shenque (CV8), but did no enhance the heat value of the lower quadrant abdomen at 30 min. Administration of ZP and its disassembled prescriptions reduced the heat value in the locations of the lower quadrant abdomen, uterus, Du channel, and Shenque (CV8) at each time point.
  
  
  CONCLUSIONS
  The drug targeting of ZP and YP focused on the locations of the Du channel and Shenque (CV8), not on the locations of the lower quadrant abdomen or uterus.
authors.forename: Xia
authors.initials: X
authors.lastname: Zheng
authors.forename: Yan-Li
authors.initials: YL
authors.lastname: Deng
authors.forename: Qi-Jia
authors.initials: QJ
authors.lastname: Li
authors.forename: Hua
authors.initials: H
authors.lastname: Lu
mesh_terms: D000328:Adult; D016503:Drug Delivery Systems; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007259:Infrared Rays; D013817:Thermography / Q000379:methods*; D055815:Young Adult
chemical_list: D004365:Drugs, Chinese Herbal; C552041:yougui; C552040:zuogui