title: Secondary oligodendroglioma after postoperative irradiation for medulloblastoma: a case report and review of the literature.
abstract: Medulloblastoma, a malignant, invasive embryonal tumor of the cerebellum, occurs most often in children. It has high metastatic potential and is usually treated by aggressive multimodal therapy, including surgery, chemotherapy and craniospinal irradiation. Multiple secondary tumors have been reported following craniospinal irradiation. It is rare with the occurrence of oligodendroglioma after irradiation. In this report, we described a patient with secondary oligodendroglioma after postoperative craniospinal irradiation for medulloblastoma.
authors.affiliation: Department of Pathology, E-DA Hospital, I-Shou University Kaohsiung, Taiwan.
authors.forename: Hong-Lin
authors.initials: HL
authors.lastname: He
authors.affiliation: Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung, Taiwan.
authors.forename: Ying-En
authors.initials: YE
authors.lastname: Lee
authors.affiliation: Department of Neurosurgery, E-DA Hospital, I-Shou University Kaohsiung, Taiwan.
authors.forename: Han-Jung
authors.initials: HJ
authors.lastname: Chen
authors.affiliation: Department of Pathology, E-DA Hospital, I-Shou University Kaohsiung, Taiwan.
authors.forename: Chao-Tien
authors.initials: CT
authors.lastname: Hsu
authors.affiliation: Department of Pathology, E-DA Hospital, I-Shou University Kaohsiung, Taiwan.
authors.forename: Yu-Yi
authors.initials: YY
authors.lastname: Huang
authors.affiliation: Department of Pathology, E-DA Hospital, I-Shou University Kaohsiung, Taiwan.
authors.forename: I-Wei
authors.initials: IW
authors.lastname: Chang
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000556:secondary* / Q000628:therapy; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008527:Medulloblastoma / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis; D019635:Neurosurgical Procedures; D009837:Oligodendroglioma / Q000175:diagnosis* / Q000556:secondary* / Q000601:surgery; D011878:Radiotherapy / Q000009:adverse effects*; D016896:Treatment Outcome
keywords: Medulloblastoma; oligodendroglioma; radiation-induced glioma