title: Carotid blood flow, cardiovascular and endocrine responses during head-up tilt in patients with acute cerebrovascular diseases.
abstract: The purpose of this study was to define common carotid blood flow (CBF), cardiovascular and endocrine responses during head-up tilt (HUT) in patients with acute cerebrovascular diseases (CVD). In 31 male patients with acute CVD (damage of the supratentorial area) and 21 age-matched control male subjects, we measured CBF, mean blood pressure (MBP), heart rate, stroke volume and cardiac output responses before (baseline), during and after HUT. We also measured plasma levels of antidiuretic hormone, adrenaline, noradrenaline, aldosterone and plasma renin activity. After obtaining baseline measurements during 3-minutes horizontal position, HUT was performed for 5 minutes, followed by continuation of recording for 3 more minutes in the horizontal position. During HUT, CBF decreased significantly and equally in both groups. MBP did not change during HUT in both groups. The endocrine responses were also not different between the two groups. The results suggest that damage to the supratentorial area in patients with acute CVD do not alter the CBF, cardiovascular and endocrine responses. In other words, HUT does not predispose patients with acute CVD to serious falls in MBP and CBF at upright posture.
authors.affiliation: Department of Rehabilitation Medicine, Wakayama Medical University, School of Medicine, 811-1 Kimiidera, 641-8509 Wakayama City, Wakayama, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Miyake
authors.affiliation: Department of Rehabilitation Medicine, Wakayama Medical University, School of Medicine, 811-1 Kimiidera, 641-8509 Wakayama City, Wakayama, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nakamura
authors.affiliation: Department of Rehabilitation Medicine, Wakayama Medical University, School of Medicine, 811-1 Kimiidera, 641-8509 Wakayama City, Wakayama, Japan.
authors.forename: Ken
authors.initials: K
authors.lastname: Kouda
authors.affiliation: Department of Rehabilitation Medicine, Wakayama Medical University, School of Medicine, 811-1 Kimiidera, 641-8509 Wakayama City, Wakayama, Japan.
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Uenishi
authors.affiliation: Department of Rehabilitation Medicine, Wakayama Medical University, School of Medicine, 811-1 Kimiidera, 641-8509 Wakayama City, Wakayama, Japan.
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Yamamoto
authors.affiliation: Department of Rehabilitation Medicine, Wakayama Medical University, School of Medicine, 811-1 Kimiidera, 641-8509 Wakayama City, Wakayama, Japan.
authors.forename: Shinji
authors.initials: S
authors.lastname: Kawasaki
authors.affiliation: Community Medical Support Center, Wakayama Medical University, 811-1 Kimiidera, 641-8509 Wakayama City, Wakayama, Japan.
authors.forename: Masami
authors.initials: M
authors.lastname: Ueno
authors.affiliation: Department of Rehabilitation Medicine, Wakayama Medical University, School of Medicine, 811-1 Kimiidera, 641-8509 Wakayama City, Wakayama, Japan.
authors.forename: Fumihiro
authors.initials: F
authors.lastname: Tajima
keywords: Blood pressure; Cardiac output; Duplex ultrasound; Noradrenaline; Stroke volume