title: Indications for cardiac resynchronization therapy.
abstract: Initial studies established patient selection criteria for cardiac resynchronization therapy (CRT) as left ventricular ejection fraction less than or equal to 35%, QRS greater than or equal to 120 ms, and New York Heart Association 3-4. Based on newer data, post hoc analyses, and meta-analyses, these criteria have been refined and guidelines updated, highlighting left bundle branch morphology and QRS greater than 150 ms in selecting patients with a likelihood of favorable outcomes. Guidelines will change as more data become available; the decision to apply CRT should be based on patient clinical profile and the balance of risk tolerance and likelihood of benefit.
authors.affiliation: The Heart and Vascular Center, The Christ Hospital, 2139 Auburn Ave, Cincinnati, OH 45219, USA.
authors.forename: Thomas M
authors.initials: TM
authors.lastname: O'Brien
authors.affiliation: The Heart and Vascular Center, The Christ Hospital, 2139 Auburn Ave, Cincinnati, OH 45219, USA.
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Schloss
authors.affiliation: The Heart and Vascular Center, The Christ Hospital, 2139 Auburn Ave, Cincinnati, OH 45219, USA. Electronic address: chunge@ohioheart.org.
authors.forename: Eugene S
authors.initials: ES
authors.lastname: Chung
mesh_terms: D054537:Atrioventricular Block / Q000628:therapy; D058406:Cardiac Resynchronization Therapy / Q000379:methods*; D002986:Clinical Trials as Topic; D006333:Heart Failure / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D009203:Myocardial Infarction / Q000628:therapy; D018579:Patient Selection; D013318:Stroke Volume / Q000502:physiology
keywords: Biventricular pacing; Cardiac resynchronization therapy; Dyssynchrony; Heart failure