title: Unusual effects of GH deficiency in adults: a review about the effects of GH on skin, sleep, and coagulation.
abstract: Based on the literature data in the last two decades, growth hormone deficiency (GHD) in adults has been accepted as a clinical entity. Due to the presence of GH and IGF-I receptors throughout the body, the physiological effects of the GH-IGF-I axis are still under investigation. The effects of GH on skin, sleep, and coagulation parameters in adults have only been investigated in detail only in the recent years. In this review, our aim was to summarize the literature regarding the effects of GHD and GH replacement treatment on the skin, sleep, and coagulation parameters in adults.
authors.affiliation: Department of Endocrinology, Erciyes University Medical School, 38039, Kayseri, Turkey.
authors.forename: F
authors.initials: F
authors.lastname: Tanriverdi
authors.forename: Z
authors.initials: Z
authors.lastname: Karaca
authors.forename: K
authors.initials: K
authors.lastname: Unluhizarci
authors.forename: F
authors.initials: F
authors.lastname: Kelestimur
mesh_terms: D000328:Adult; D001778:Blood Coagulation Disorders / Q000209:etiology* / Q000473:pathology; D019382:Human Growth Hormone / Q000172:deficiency*; D006801:Humans; D007018:Hypopituitarism / Q000150:complications* / Q000473:pathology; D012867:Skin / Q000473:pathology*; D012893:Sleep Wake Disorders / Q000209:etiology* / Q000473:pathology; D013546:Sweating
chemical_list: D019382:Human Growth Hormone