title: RNase AS versus RNase T: similar yet different.
abstract: In this issue of Structure, Romano and colleagues show that RNase AS specifically hydrolyses adenylate-containing RNA and affects mycobacterial virulence. This study reveals the structural basis underlying the substrate specificity of this enzyme.
authors.affiliation: Institute of Molecular and Cell Biology, 61 Biopolis Drive, Proteos, Singapore 138673, Singapore.
authors.forename: Xuhua
authors.initials: X
authors.lastname: Tang
authors.affiliation: Institute of Molecular and Cell Biology, 61 Biopolis Drive, Proteos, Singapore 138673, Singapore.
authors.forename: Siew Choo
authors.initials: SC
authors.lastname: Lim
authors.affiliation: Institute of Molecular and Cell Biology, 61 Biopolis Drive, Proteos, Singapore 138673, Singapore. Electronic address: haiwei@imcb.a-star.edu.sg.
authors.forename: Haiwei
authors.initials: H
authors.lastname: Song
mesh_terms: D000818:Animals; D009169:Mycobacterium tuberculosis / Q000472:pathogenicity*; D012260:Ribonucleases / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D012260:Ribonucleases