title: H2 unimolecular elimination in electrospray ionization mass spectrometry from erythraline, a spirocyclic alkaloid.
abstract: Erythrina alkaloids, which contain a spirocyclic structure, are well known due to their important biological activity at the central nervous system. In this study, systematic electrospray ionization tandem mass spectrometry (ESI-MS/MS) and ESI-multistage mass spectrometry (MS(n)) analysis of erythraline have shown an unexpected H2 neutral elimination reaction. We have investigated the formation of these ions by accurate-mass ESI-MS/MS with different analyzers and the data suggest a possible unimolecular reaction of H2 loss.
authors.forename: Denise Brentan
authors.initials: DB
authors.lastname: Silva
authors.forename: Thais
authors.initials: T
authors.lastname: Guaratini
authors.forename: Ricardo
authors.initials: R
authors.lastname: Vessecchi
authors.forename: Norberto Peporine
authors.initials: NP
authors.lastname: Lopes
authors.forename: Benedikt
authors.initials: B
authors.lastname: Cramer
authors.forename: Hans-Ulrich
authors.initials: HU
authors.lastname: Humpf
authors.forename: João Luis Callegari
authors.initials: JL
authors.lastname: Lopes
mesh_terms: D026121:Indole Alkaloids / Q000737:chemistry*; D007477:Ions / Q000737:chemistry*; D008968:Molecular Conformation; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*
chemical_list: D026121:Indole Alkaloids; D007477:Ions; C586471:erythraline