title: Male fertility preservation, where are we in 2014?
abstract: Male fertility preservation receives growing attention in the field of reproductive medicine. The first clinical programs were established to preserve reproductive potential in men needing gonadotoxic treatment. Sperm cryopreservation is now a standard procedure. Since a few years, several centres offer testicular tissue cryopreservation to prepubertal boys. This method is still experimental and further research is needed to implement the transplantation techniques in the clinic. With the aim to preserve or restore fertility in patients affected by other diseases (Klinefelter syndrome, Sertoli cell only syndrome), techniques for in vitro spermatogenesis are being developed.
authors.affiliation: Research group biology of testis, department of embryology and genetics, Vrije universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium. Electronic address: ellen.goossens@uzbrussel.be.
authors.forename: Ellen
authors.initials: E
authors.lastname: Goossens
authors.affiliation: Research group biology of testis, department of embryology and genetics, Vrije universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium.
authors.forename: Herman
authors.initials: H
authors.lastname: Tournaye
mesh_terms: D000293:Adolescent; D053687:Adult Stem Cells / Q000637:transplantation; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D064592:Autografts; D002648:Child; D015925:Cryopreservation / Q000379:methods; D059247:Fertility Preservation / Q000379:methods* / Q000639:trends; D006801:Humans; D007248:Infertility, Male / Q000209:etiology; D007713:Klinefelter Syndrome / Q000150:complications; D008297:Male; D054331:Sertoli Cell-Only Syndrome / Q000150:complications; D013074:Sperm Banks; D053625:Sperm Retrieval; D013091:Spermatogenesis; D013736:Testicular Neoplasms / Q000150:complications / Q000188:drug therapy; D013737:Testis / Q000637:transplantation
chemical_list: D000970:Antineoplastic Agents
keywords: Cellules souches spermatogoniales; Fertility preservation; Gonadotoxic treatment; Klinefelter; La préservation de la fertilité; Le traitement gonadotoxique; Spermatogenesis; Spermatogenèse; Spermatogonial stem cell