title: Modulation of neural circuits: how stimulus context shapes innate behavior in Drosophila.
abstract: Remarkable advances have been made in recent years in our understanding of innate behavior and the underlying neural circuits. In particular, a wealth of neuromodulatory mechanisms have been uncovered that can alter the input-output relationship of a hereditary neural circuit. It is now clear that this inbuilt flexibility allows animals to modify their behavioral responses according to environmental cues, metabolic demands and physiological states. Here, we discuss recent insights into how modulation of neural circuits impacts innate behavior, with a special focus on how environmental cues and internal physiological states shape different aspects of feeding behavior in Drosophila.
authors.affiliation: Neurobiology Section, Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, United States.
authors.forename: Chih-Ying
authors.initials: CY
authors.lastname: Su
authors.affiliation: Neurobiology Section, Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, United States. Electronic address: jw800@ucsd.edu.
authors.forename: Jing W
authors.initials: JW
authors.lastname: Wang
mesh_terms: D000818:Animals; D001070:Appetitive Behavior / Q000502:physiology*; D002245:Carbon Dioxide / Q000494:pharmacology; D004330:Drosophila; D004924:Escape Reaction / Q000187:drug effects; D007323:Instinct; D009415:Nerve Net / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D012527:Satiation; D012528:Satiety Response
chemical_list: D002245:Carbon Dioxide