title: Twenty-eight day Holter monitoring is poorly tolerated and insensitive for paroxysmal atrial fibrillation detection in cryptogenic stroke.
abstract: This pilot study in a prospective cohort of 20 cryptogenic stroke patients showed that a significant proportion has paroxysmal atrial fibrillation undetected by 24-h Holter monitoring. However, longer monitoring with 28-day Holter was poorly tolerated and still insufficiently sensitive for paroxysmal atrial fibrillation detection. Further studies are urgently needed to elucidate the optimal timing, method and duration of cardiac rhythm monitoring following ischaemic stroke.
authors.affiliation: University Department of Medicine, The University of Melbourne, Melbourne, Victoria, Australia; Department of Neurology, The University of Melbourne, Melbourne, Victoria, Australia.
authors.forename: H T
authors.initials: HT
authors.lastname: Tu
authors.forename: S
authors.initials: S
authors.lastname: Spence
authors.forename: J M
authors.initials: JM
authors.lastname: Kalman
authors.forename: S M
authors.initials: SM
authors.lastname: Davis
mesh_terms: D000368:Aged; D058070:Asymptomatic Diseases; D001281:Atrial Fibrillation / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D018880:Atrial Premature Complexes / Q000175:diagnosis / Q000453:epidemiology; D002545:Brain Ischemia / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D002318:Cardiovascular Diseases / Q000453:epidemiology; D015897:Comorbidity; D003920:Diabetes Mellitus / Q000453:epidemiology; D015716:Electrocardiography, Ambulatory / Q000523:psychology; D005188:False Negative Reactions; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care; D010865:Pilot Projects; D011446:Prospective Studies; D012008:Recurrence; D012494:Sampling Studies; D012680:Sensitivity and Specificity
keywords: Holter monitoring; atrial fibrillation; diagnosis; screening; stroke