title: [Alcohol-related dementia].
abstract: Excessive alcohol use is associated with health problems for the elderly in combination with their chronic conditions. One such complication, alcohol-related dementia (ARD) is brought about by direct or indirect ethanol intoxication, and coexisting nutritional deficiency, liver disease, cerebrovascular disease and traumatic brain injury. The elderly people with ARD have been underestimated and underdiagnosed. In these older alcoholics, atrophic changes, lacunar infarcts and deep white matter lesions of the brain are evident and are associated not only with their cognitive decline, but also with their frailty, leading to high morbidity and mortality ratio. Although lifelong abstinence can recover patients with ARD to temporally lull, aging, the severity of alcohol dependence, and the concomitant nutritional, physical and environmental factors can all impact negatively their outcome. Therefore, a comprehensive approach to lifestyle factors is recommended so that they can minimize preventable risks and maintain health status. Nursing home placement may be an appropriate treatment option for some refractory, long-term patients with ARD.
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Matsui
authors.forename: Akira
authors.initials: A
authors.lastname: Yokoyama
authors.forename: Sachio
authors.initials: S
authors.lastname: Matsushita
authors.forename: Koichi
authors.initials: K
authors.lastname: Kozaki
authors.forename: Susumu
authors.initials: S
authors.lastname: Higuchi
mesh_terms: D000368:Aged; D019973:Alcohol-Related Disorders; D000437:Alcoholism / Q000503:physiopathology; D003704:Dementia / Q000209:etiology*; D006801:Humans