title: How reactive oxygen species and proline face stress together.
abstract: Reactive oxygen species (ROS) are continuously generated as a consequence of plant metabolic processes due to incomplete reduction of O2. Previously considered to be only toxic by-products of metabolism, ROS are now known to act as second messengers in intracellular signalling cascades to trigger tolerance of various abiotic and biotic stresses. The accumulation of proline is frequently observed during the exposure of plants to adverse environmental conditions. Interestingly proline metabolism may also contribute to ROS formation in mitochondria, which play notably a role in hypersensitive response in plants, life-span extension in worms and tumor suppression in animals. Here we review current knowledge about the regulation of proline metabolism in response to environmental constraints and highlight the key role of ROS in the regulation of this metabolism. The impact of proline on ROS generation is also investigated. Deciphering and integrating these relationships at the whole plant level will bring new perspectives on how plants adapt to environmental stresses.
authors.affiliation: Université Pierre & Marie Curie (UPMC), Univ. Paris 6, APCE, URF5, Case 156, 4 place Jussieu, 75252 Paris cedex 05, France; Laboratoire des Plantes Extrêmophiles, Centre de Biotechnologie de Borj-Cedria (CBBC), BP 901, Hammam-Lif 2050, Tunisia.
authors.forename: Kilani
authors.initials: K
authors.lastname: Ben Rejeb
authors.affiliation: Laboratoire des Plantes Extrêmophiles, Centre de Biotechnologie de Borj-Cedria (CBBC), BP 901, Hammam-Lif 2050, Tunisia.
authors.forename: Chedly
authors.initials: C
authors.lastname: Abdelly
authors.affiliation: Université Pierre & Marie Curie (UPMC), Univ. Paris 6, APCE, URF5, Case 156, 4 place Jussieu, 75252 Paris cedex 05, France. Electronic address: arnould.savoure@upmc.fr.
authors.forename: Arnould
authors.initials: A
authors.lastname: Savouré
mesh_terms: D018506:Gene Expression Regulation, Plant; D018384:Oxidative Stress / Q000502:physiology; D011392:Proline / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000378:metabolism*; D013312:Stress, Physiological
chemical_list: D017382:Reactive Oxygen Species; D011392:Proline
keywords: Abiotic stress tolerance; Proline metabolism; ROS signalling; Reactive oxygen species (ROS); Redox homeostasis