title: Collateral damage: depressive symptoms in the partners of COPD patients.
abstract: BACKGROUND
  Depression is a frequent comorbidity in COPD patients and is associated with greater physical impairment, increased health-care utilization, and worse outcomes. The presence of depressive symptoms in the partners of COPD patients has not been evaluated.
  
  
  METHODS
  We evaluated the partners of 230 consecutive COPD patients included in a prospective study. Depressive symptoms were evaluated using Beck's Depression Inventory (BDI) on the first day of admission for COPD exacerbation. Patients were followed-up for 1 year.
  
  
  RESULTS
  Significant depressive symptoms were present in 39.6 % of the COPD patients and in 40.9 % of their partners. Beck scores were higher in the partners of patients with severe airflow obstruction and in those with ≥2 exacerbations and ≥1 hospitalizations for COPD exacerbation during the 1-year follow-up. The BDI score of the patients' partners was significantly correlated with the BDI score of the COPD patients (r s = 0.422). In multivariate analysis, depressive symptoms in the COPD patients were an independent predictor of depressive symptoms in their partners (OR 4.136, 95 % CI 1.991-8.594; p < 0.001).
  
  
  CONCLUSIONS
  A large proportion of the partners of COPD patients present significant depressive symptoms. The identification of those patients and their partners represents a possible target for intervention.
authors.affiliation: 3rd Respiratory Medicine Department, Sismanogleion General Hospital, Sismanogleiou 1 Str, 15126, Athens, Greece.
authors.forename: Andriana I
authors.initials: AI
authors.lastname: Papaioannou
authors.forename: Stamatoula
authors.initials: S
authors.lastname: Tsikrika
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Bartziokas
authors.forename: Foteini
authors.initials: F
authors.lastname: Karakontaki
authors.forename: Emmanouil
authors.initials: E
authors.lastname: Kastanakis
authors.forename: Filia
authors.initials: F
authors.lastname: Diamantea
authors.forename: Aikaterini
authors.initials: A
authors.lastname: Haniotou
authors.forename: Spyros
authors.initials: S
authors.lastname: Papiris
authors.forename: Vlassis
authors.initials: V
authors.lastname: Polychronopoulos
authors.forename: Stelios
authors.initials: S
authors.lastname: Loukides
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Kostikas
mesh_terms: D000368:Aged; D015897:Comorbidity; D017281:Cost of Illness; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology*; D005260:Female; D006115:Greece / Q000453:epidemiology; D006760:Hospitalization; D006801:Humans; D016015:Logistic Models; D008168:Lung / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D029424:Pulmonary Disease, Chronic Obstructive / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000523:psychology* / Q000628:therapy; D011788:Quality of Life; D012307:Risk Factors; D012720:Severity of Illness Index; D018454:Spouses / Q000523:psychology*; D011795:Surveys and Questionnaires; D013997:Time Factors