title: Comparison of the antimicrobial effect of heavy silicone oil and conventional silicone oil against endophthalmitis-causing agents.
abstract: OBJECTIVE
  To conduct an in vitro experimental study comparing the effectiveness of conventional silicone oil and heavy silicone oil against endophthalmitis-causing agents.
  
  
  METHODS
  The antimicrobial activity of conventional silicone oil (RS OIL 5000) and heavy silicone oil (heavySil 1500) was tested. The antimicrobial effects of both silicone oils were determined by the growing capability of the microorganism.
  
  
  RESULTS
  The number of Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa, and Candida albicans decreased to zero levels at the second day of inoculation in heavy silicone oil. In conventional silicone oil, the microorganisms survived longer than in heavy silicone oil.
  
  
  CONCLUSIONS
  Heavy silicone oil seems to be more effective than conventional silicone oil against endophthalmitis-causing agents.
authors.forename: Nurgül
authors.initials: N
authors.lastname: Ornek
authors.forename: Teoman
authors.initials: T
authors.lastname: Apan
authors.forename: Reyhan
authors.initials: R
authors.lastname: Oğurel
authors.affiliation: Department of Ophthalmology , School of Medicine, Kirikkale University, Turkey.
authors.forename: Kemal
authors.initials: K
authors.lastname: Ornek
mesh_terms: D001419:Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D015169:Colony Count, Microbial; D009877:Endophthalmitis / Q000188:drug therapy* / Q000382:microbiology; D005123:Eye / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000188:drug therapy* / Q000382:microbiology; D015821:Eye Infections, Fungal / Q000188:drug therapy* / Q000382:microbiology; D005658:Fungi / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D012827:Silicone Oils / Q000494:pharmacology*
chemical_list: D012827:Silicone Oils; C515608:densiron