title: Alkene-assisted nickel-catalyzed regioselective 1,4-addition of organoboronic acid to dienones: a direct route to all-carbon quaternary centers.
abstract: A nickel-catalyzed highly regioselective 1,4-addition reaction of boronic acids to dienones to form products with an all-carbon quaternary center is described. The 3-alkenyl group of dienones is the key for the reaction to proceed smoothly. A mechanism involving the coordination of the dienyl group to the nickel center is proposed.
authors.affiliation: Department of Chemistry, National Tsing Hua University , Hsinchu 30013, Taiwan.
authors.forename: Ya-Chun
authors.initials: YC
authors.lastname: Hong
authors.forename: Parthasarathy
authors.initials: P
authors.lastname: Gandeepan
authors.forename: Subramaniyan
authors.initials: S
authors.lastname: Mannathan
authors.forename: Wei-Tse
authors.initials: WT
authors.lastname: Lee
authors.forename: Chien-Hong
authors.initials: CH
authors.lastname: Cheng
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D001897:Boronic Acids; D002244:Carbon; D009532:Nickel