title: Retrospective analysis of 80 cases with uterine carcinosarcoma, leiomyosarcoma and endometrial stromal sarcoma in China, 1988-2007.
abstract: OBJECTIVE
  Uterine sarcomas are rare gynecological malignancies with poor prognosis and high mortality. We provides clinical information of uterine sarcoma patients at Changhai Hospital of Secondary Military Medical University in Shanghai, China, over a 20-year period.
  
  
  METHODS
  Satisfied the criteria for the study, a total of 80 female patients with uterine sarcomas were retrospectively evaluated. Overall survival was analyzed by Kaplan-Meier method.
  
  
  METHODS
  The following information was extracted from our medical records: age, presentations, blood types, stages, ultrasonographic results, therapies and follow-up.
  
  
  RESULTS
  Of the 80 patients, the mean age of onset was 57.3±2.03 years, and the highest frequency occurred in 51-60 age group. Endometrial stromal sarcoma was the most common histological type (47.5%). Even population of these patients presented was with early stage (I&II) and advanced stages (III&IV). Among 79 patients underwent primary surgery, 74 cases was hysterectomy and bilateral salping-ooophorectomy. Equal to disease-specific survival, overall survival rates at 1-, 3- and 5-year were 81.3%, 62.5% and 40% respectively. Age, menopausal status, blood type, stage, and pathologic types were all proved to be correlated with the survival.
  
  
  CONCLUSIONS
  Our retrospective data in part reflect clinical characteristics of uterine sarcoma in China, and form the basis for further concerning researches.
authors.affiliation: Department of Gynecology and Obstetrics, Changhai Hospital of Secondary Military Medical University Shanghai, 200433, China ; Department of Gynecology and Obstetrics, General Hospital of PLA Beijing, 100853, China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Gao
authors.affiliation: Department of Orthopedics, Air Force General Hospital Beijing, 100142, China ; Department of Orthopedics, Military General Hospital of Beijing PLA Beijing, 100700, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Meng
authors.affiliation: Department of Gynecology and Obstetrics, Changhai Hospital of Secondary Military Medical University Shanghai, 200433, China.
authors.forename: Yemin
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Gynecology and Obstetrics, Changhai Hospital of Secondary Military Medical University Shanghai, 200433, China.
authors.forename: Tingting
authors.initials: T
authors.lastname: Jiao
authors.affiliation: Department of Gynecology and Obstetrics, Changhai Hospital of Secondary Military Medical University Shanghai, 200433, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Hui
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002296:Carcinosarcoma / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology; D002681:China / Q000453:epidemiology; D016889:Endometrial Neoplasms / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology; D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D015994:Incidence; D053208:Kaplan-Meier Estimate; D007890:Leiomyosarcoma / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology; D008875:Middle Aged; D009367:Neoplasm Staging; D012189:Retrospective Studies; D018203:Sarcoma, Endometrial Stromal / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology; D015996:Survival Rate; D014594:Uterine Neoplasms / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology
keywords: Carcinosarcoma; China; blood type; endometrial stromal sarcoma; leiomyosarcoma; prognosis