title: Lung abscess due to Streptococcus pneumoniae: a case series and brief review of the literature.
abstract: Anaerobes used to be the most common cause of community-acquired lung abscess, and Streptococcus species used to be the second most common cause. In recent years, this has been changing. Klebsiella pneumoniae is now an increasing cause of community- acquired lung abscess, but Streptococcus species continue to be major pathogens. Necrotizing pneumonia has generally been regarded as a rare complication of pneumococcal infection in adults. Type 3 Streptococcus pneumoniae was the single most common type implicated in necrosis; however, many other serotypes were implicated. This entity predominately infects children, but is present also in adults. Lung abscess in adults due to Streptococcus pneumoniae is not common. In this regard we present a case series of pulmonary cavitation due to Streptococcus pneumoniae and discuss the possible pathogenic mechanism of the disease.
authors.affiliation: antonello.nicolini@fastwebnet.it.
authors.forename: Antonello
authors.initials: A
authors.lastname: Nicolini
authors.forename: Catia
authors.initials: C
authors.lastname: Cilloniz
authors.forename: Renata
authors.initials: R
authors.lastname: Senarega
authors.forename: Gianluca
authors.initials: G
authors.lastname: Ferraioli
authors.forename: Cornelius
authors.initials: C
authors.lastname: Barlascini
mesh_terms: D001421:Bacteria, Anaerobic / Q000302:isolation & purification*; D017714:Community-Acquired Infections / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D006801:Humans; D007711:Klebsiella pneumoniae / Q000302:isolation & purification; D008169:Lung Abscess / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology*; D013296:Streptococcus pneumoniae / Q000302:isolation & purification*