title: Post-kidney transplant large bowel lymphoproliferative disorder.
abstract: Epstein-Barr virus (EBV)-associated post-transplant lymphoproliferative disorder (PTLD) is a serious complication of organ transplantation. The gastrointestinal (GI) tract is a common site involved, but non-specific signs and symptoms often delay the diagnosis. We report a case of EBV-associated GI-PTLD in a 68-year-old kidney transplant patient who received the kidney ten months earlier. He presented with chronic diarrhea and developed massive pneumo-peritoneum secondary to multiple colonic perforations.
authors.affiliation: Department of Internal Medicine, Division of Nephrology, The Ohio State University Medical Center, Columbus, OH, USA.
authors.forename: Neeraj
authors.initials: N
authors.lastname: Singh
authors.forename: Singh
authors.initials: S
authors.lastname: Samavedi
authors.forename: Amer
authors.initials: A
authors.lastname: Rajab
mesh_terms: D000368:Aged; D001706:Biopsy; D002908:Chronic Disease; D003082:Colectomy; D003108:Colonic Diseases / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery / Q000821:virology; D003967:Diarrhea / Q000209:etiology; D020031:Epstein-Barr Virus Infections / Q000175:diagnosis / Q000209:etiology* / Q000821:virology; D017809:Fatal Outcome; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology; D016030:Kidney Transplantation / Q000009:adverse effects*; D008232:Lymphoproliferative Disorders / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery / Q000821:virology; D008297:Male; D011027:Pneumoperitoneum / Q000209:etiology; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome