title: A single thiazole orange molecule forms an exciplex in a DNA i-motif.
abstract: A fluorescent exciplex of thiazole orange (TO) is formed in a single-dye conjugated DNA i-motif. The exciplex fluorescence exhibits a large Stokes shift, high quantum yield, robust response to pH oscillation and little structural disturbance to the DNA quadruplex, which can be used to monitor the folding of high-order DNA structures.
authors.affiliation: Division of Chemistry and Biological Chemistry, Nanyang Technological University, 21 Nanyang Link, Singapore 637371, Singapore. fwshao@ntu.edu.sg.
authors.forename: Baochang
authors.initials: B
authors.lastname: Xu
authors.forename: Xiangyang
authors.initials: X
authors.lastname: Wu
authors.forename: Edwin K L
authors.initials: EK
authors.lastname: Yeow
authors.forename: Fangwei
authors.initials: F
authors.lastname: Shao
mesh_terms: D052160:Benzothiazoles / Q000138:chemical synthesis / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D015394:Molecular Structure; D011804:Quinolines / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D052160:Benzothiazoles; D005456:Fluorescent Dyes; D011804:Quinolines; C051000:thiazole orange; D004247:DNA