title: Copper-catalyzed cross-coupling of vinylsiloxanes with bromoalkynes: synthesis of enynes.
abstract: Enynes are versatile building blocks in organic synthesis. A copper-catalyzed Hiyama-type cross-coupling of vinylsiloxanes with bromoalkynes is presented. This mild and efficient method led to the formation of various sensitive enynes. The use of cis, trans, and 1,1'-disubstituted vinylsiloxanes was allowed, and full retention of stereochemistry was observed. Sensitive groups such as halides, unsaturated ketones, and aldehydes were fully tolerated.
authors.affiliation: Institute of Condensed Matter and Nanosciences, Molecules, Solids and Reactivity (IMCN/MOST), - Université Catholique de Louvain , Place Louis Pasteur 1, bte L4.01.02, 1348 Louvain-la-Neuve, Belgium.
authors.forename: Loïc
authors.initials: L
authors.lastname: Cornelissen
authors.forename: Maxime
authors.initials: M
authors.lastname: Lefrancq
authors.forename: Olivier
authors.initials: O
authors.lastname: Riant