title: Effect of intraocular lens diameter implanted in enucleated porcine eye on intraocular pressure induced by scleral depression.
abstract: The effect of the diameter of an intraocular lens (IOL) implanted in enucleated porcine eyes on the intraocular pressure induced by scleral depression was investigated. Two IOLs of 6 mm and 7 mm optic diameter were implanted. The intraocular pressure (IOP) was monitored during scleral depression by a transducer placed in the midvitreous through a sclerotomy at 6 o'clock. The area under the curve (AUC) of the IOP changes from the beginning of the indentation to the point when the peripheral retinal surface was observed through the IOL optics was measured. The AUC was significantly larger in eyes with a 6 mm IOL than in eyes with a 7 mm IOL (p < 0.05). The IOP elevation at the endpoint was higher in eyes with the 6 mm IOL than in eyes with the 7 mm IOL. We conclude that the AUC may represent the degree of stress induced by scleral depression. The higher AUC value with the X-60 may be because of the longer distance from the peripheral retina to the edge of the IOL optics.
authors.affiliation: Department of Ophthalmology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8605, Japan.
authors.forename: Gaku
authors.initials: G
authors.lastname: Terauchi
authors.affiliation: Department of Ophthalmology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8605, Japan ; Matsumoto Eye Clinic, 50-2 Takagaki, Awa-cho, Awa-shi, Tokushima 771-1705, Japan.
authors.forename: Celso Soiti
authors.initials: CS
authors.lastname: Matsumoto
authors.affiliation: Department of Ophthalmology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8605, Japan.
authors.forename: Kei
authors.identifier: 0000-0002-1543-9345
authors.initials: K
authors.lastname: Shinoda
authors.affiliation: Matsumoto Eye Clinic, 50-2 Takagaki, Awa-cho, Awa-shi, Tokushima 771-1705, Japan.
authors.forename: Harue
authors.initials: H
authors.lastname: Matsumoto
authors.affiliation: Department of Ophthalmology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8605, Japan.
authors.forename: Atsushi
authors.identifier: 0000-0001-6446-3467
authors.initials: A
authors.lastname: Mizota
mesh_terms: D000818:Animals; D007429:Intraocular Pressure / Q000502:physiology*; D007910:Lenses, Intraocular; D008954:Models, Biological; D009799:Ocular Physiological Phenomena; D012590:Sclera / Q000502:physiology; D013552:Swine