title: Conditioned taste aversion, drugs of abuse and palatability.
abstract: We consider conditioned taste aversion to involve a learned reduction in the palatability of a taste (and hence in amount consumed) based on the association that develops when a taste experience is followed by gastrointestinal malaise. The present article evaluates the well-established finding that drugs of abuse, at doses that are otherwise considered rewarding and self-administered, cause intake suppression. Our recent work using lick pattern analysis shows that drugs of abuse also cause a palatability downshift and, therefore, support conditioned taste aversion learning.
authors.affiliation: University of Illinois at Chicago, United States. Electronic address: jlin2@uic.edu.
authors.forename: Jian-You
authors.initials: JY
authors.lastname: Lin
authors.affiliation: University of Illinois at Chicago, United States.
authors.forename: Joe
authors.initials: J
authors.lastname: Arthurs
authors.affiliation: University of Illinois at Chicago, United States. Electronic address: sreilly@uic.edu.
authors.forename: Steve
authors.initials: S
authors.lastname: Reilly
mesh_terms: D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects* / Q000502:physiology; D003213:Conditioning, Psychological / Q000187:drug effects* / Q000502:physiology; D005518:Food Preferences / Q000187:drug effects* / Q000502:physiology / Q000523:psychology; D006801:Humans; D013287:Illicit Drugs; D019966:Substance-Related Disorders / Q000503:physiopathology* / Q000523:psychology; D055697:Taste Perception / Q000187:drug effects* / Q000502:physiology
chemical_list: D013287:Illicit Drugs
keywords: Conditioned taste aversion; Danger signal; Drugs of abuse; Lick pattern analysis; Palatability; Taste avoidance learning; Taste neophobia; Taste reactivity