title: [Comparative study of histological results between resection and biopsy of the prostate].
abstract: OBJECTIVE
  To evaluate the histological correlation between transuretral resection chips and biopsy cores within a population of patients who underwent resection of prostate (TURP) and prostate biopsies (BPx).
  
  
  METHODS
  Clinical and tumoral data of 77 patients who had both procedures simultaneously or with a slight delay were collected. According to the presence of prostate cancer (Pca), 4 groups were defined: group 1 (TURP and BPx negative), group 2 (TURP positive, BPx negative), group 3 (TURP negative, BPx positive), group 4 (TURP and BPx positive). Means and proportions were compared using Anova and χ(2) test, respectively.
  
  
  RESULTS
  The patients were older in groups 3 and 4 (79 and 76 respectively, P=0.65). The PSA was higher in the groups 3 and 4 (64 and 55 ng/mL) than the groups 1 and 2 (10.6 et 16 respectively, P=0.23). The number of positive biopsy was higher in the group 4 than the group 3 (5.6 vs. 4.6, P<0.0001), the chips were more invaded in the group 4 than the group 2 (41% vs. 11% P<0.0001), the Gleason score at TURP was higher in the group 4 than the group 2 (7.5 vs. 6.2 P<0.0001).
  
  
  CONCLUSIONS
  Our study underlines that the Pca of transition and peripheral zones seems to have distinct characteristics. When chips of TURP and BPx were both invaded, it was due to an aggressive cancer. The decision to explore the peripheral zone in the case of positive TURP must take clinical context into consideration.
authors.affiliation: Service d'urologie, CHU de Rennes, hôpital Pontchaillou, 2, rue Henri-Le-Guillou, 35000 Rennes, France. Electronic address: romain.MATHIEU@chu-rennes.fr.
authors.forename: R
authors.initials: R
authors.lastname: Mathieu
authors.affiliation: Service d'urologie, CHU de Rennes, hôpital Pontchaillou, 2, rue Henri-Le-Guillou, 35000 Rennes, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Tibari
authors.affiliation: Service d'urologie, CHU de Rennes, hôpital Pontchaillou, 2, rue Henri-Le-Guillou, 35000 Rennes, France.
authors.forename: G
authors.initials: G
authors.lastname: Verhoest
authors.affiliation: Service d'urologie, CHU de Rennes, hôpital Pontchaillou, 2, rue Henri-Le-Guillou, 35000 Rennes, France.
authors.forename: S
authors.initials: S
authors.lastname: Vincendeau
authors.affiliation: Service d'urologie, CHU de Rennes, hôpital Pontchaillou, 2, rue Henri-Le-Guillou, 35000 Rennes, France.
authors.forename: A
authors.initials: A
authors.lastname: Manunta
authors.affiliation: Service d'anatomocytopathologie, CHU de Rennes, 35042 Rennes, France.
authors.forename: N
authors.initials: N
authors.lastname: Rioux-Leclercq
authors.affiliation: Service d'urologie, CHU de Rennes, hôpital Pontchaillou, 2, rue Henri-Le-Guillou, 35000 Rennes, France.
authors.forename: K
authors.initials: K
authors.lastname: Bensalah
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D014408:Biomarkers, Tumor / Q000097:blood*; D062005:Biopsy, Large-Core Needle / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D060787:Neoplasm Grading; D011379:Prognosis; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood / Q000473:pathology* / Q000601:surgery*; D012189:Retrospective Studies; D020728:Transurethral Resection of Prostate / Q000379:methods
chemical_list: D014408:Biomarkers, Tumor; D017430:Prostate-Specific Antigen
keywords: Anatomopathologie; Biopsie de prostate; Cancer de prostate; Prostate biopsy; Prostatic neoplasm; Résection de prostate; Transurethral resection of the prostate