title: Clinical presentation of eosinophilic esophagitis in adults.
abstract: Eosinophilic esophagitis (EoE) is an increasingly recognized immune antigen-mediated esophageal disease found in both children and adults. It is defined as a clinicopathologic disease characterized by symptoms of esophageal dysfunction accompanied by an eosinophil-predominant esophageal inflammation that occurs in the absence of other causes of esophageal eosinophilia. Classic symptoms in adults include dysphagia to solids and food bolus impaction but a variety of other symptoms are also encountered. Despite the increasing awareness of EoE among practicing physicians, a long delay from onset of symptoms to diagnosis remains a problem in this disease.
authors.affiliation: Division of Gastroenterology, Hospital of the University of Pennsylvania, University of Pennsylvania Perelman School of Medicine, 9 Penn Tower, One Convention Avenue, Philadelphia, PA 19104, USA. Electronic address: gary.falk@uphs.upenn.edu.
authors.forename: Gary W
authors.initials: GW
authors.lastname: Falk
mesh_terms: D000328:Adult; D003680:Deglutition Disorders / Q000209:etiology; D057765:Eosinophilic Esophagitis / Q000150:complications / Q000175:diagnosis*; D004945:Esophagoscopy; D006801:Humans
keywords: Dysphagia; Endoscopy; Eosinophilic esophagitis; Esophageal eosinophilia; Gastroesophageal reflux disease; Narrow-caliber esophagus; PPI-responsive esophageal eosinophilia