title: [Chronic kidney disease in 5 708 people receiving physical examination].
abstract: OBJECTIVE
  To investigate chronic kidney disease (CKD) and its risk factors in people receiving physical examination.
  
  
  METHODS
  This retrospective study included people over 20 years old who had physical examination in the Health Management Center of Third Xiangya Hospital from Janurary 2008 to June 2011. CKD and its risk factors as well as questionnaire were recorded. The risk factors were analyzed by multivariate logistic analysis. CKD was defined by kidney damage (microalbuminuria≥30 mg/L) and/or hematuria and/or reduced kidney function [evaluate glomerular filtration rate (eGFR)<60 mL/(min.1.73 m2)]. We counted eGFR according to the modification of diet in renal disease (MDRD).
  
  
  RESULTS
  A total of 5 708 physical examination reports were included. The detection rate of albuminuria, reduced renal function and hematuria was 25.0%, 1.7% and 1.1%. The detection rate of CKD was 25.6%, and detection rate of CKD stage 1-5 was 17.8%, 6.7%, 1.1%, 0 and 0, respectively. Multivariate logistic analysis indicated that diabetes mellitus, hypertension, hypercholesterolemia, male, age, and smoking were the risk factors for CKD. Increasing physical activity was the protective factor against CKD.
  
  
  CONCLUSIONS
  High prevalence of CKD in people receiving physical examination is found in Changsha, especially stage 1 and 2 CKD. Physical examination is important to screen CKD. Stopping smoking, control of blood glucose, blood pressure, blood lipids and increasing physical activity may help reduce the prevalence of CKD.
authors.affiliation: Health Management Center, Third Xiangya Hospital, Central South University, Changsha 410013, China.
authors.forename: Guo
authors.initials: G
authors.lastname: Xu
authors.forename: Zhiheng
authors.initials: Z
authors.lastname: Chen
authors.forename: Hao
authors.initials: H
authors.lastname: Zhang
authors.forename: Ni
authors.initials: N
authors.lastname: Gong
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000419:Albuminuria; D001786:Blood Glucose; D003920:Diabetes Mellitus; D005919:Glomerular Filtration Rate; D006801:Humans; D006973:Hypertension; D007674:Kidney Diseases; D008297:Male; D015999:Multivariate Analysis; D010808:Physical Examination; D015995:Prevalence; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D011795:Surveys and Questionnaires
chemical_list: D001786:Blood Glucose