title: Early preinvasive lesions in ovarian cancer.
abstract: Faced with the catastrophic prognosis for ovarian cancer due to the fact that it is most often diagnosed late at the peritoneal carcinomatosis stage, screening and early detection could probably reduce the mortality rate. A better understanding of the molecular characteristics of the different ovarian cancer subtypes and their specific molecular signatures is indispensable prior to development of new screening strategies. We discuss here the early natural history of ovarian cancer and its origins.
authors.affiliation: Department of Gynecology, Hôpital Femme Mère Enfant (HFME), University Hospital Lyon, 69000 Lyon, France.
authors.forename: Gautier
authors.initials: G
authors.lastname: Chene
authors.affiliation: Department of Gynecology, Hôpital Femme Mère Enfant (HFME), University Hospital Lyon, 69000 Lyon, France.
authors.forename: Gery
authors.initials: G
authors.lastname: Lamblin
authors.affiliation: Department of Gynecology, Hôpital Femme Mère Enfant (HFME), University Hospital Lyon, 69000 Lyon, France.
authors.forename: Karine
authors.initials: K
authors.lastname: Le Bail-Carval
authors.affiliation: Department of Gynecology, Hôpital Femme Mère Enfant (HFME), University Hospital Lyon, 69000 Lyon, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Chabert
authors.affiliation: Department of Gynecology, Hôpital Femme Mère Enfant (HFME), University Hospital Lyon, 69000 Lyon, France.
authors.forename: Naoual
authors.initials: N
authors.lastname: Bakrin
authors.affiliation: Department of Gynecology, Hôpital Femme Mère Enfant (HFME), University Hospital Lyon, 69000 Lyon, France.
authors.forename: Georges
authors.initials: G
authors.lastname: Mellier
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics*; D055088:Early Detection of Cancer; D005260:Female; D006801:Humans; D060787:Neoplasm Grading; D010051:Ovarian Neoplasms / Q000209:etiology* / Q000235:genetics* / Q000473:pathology; D011379:Prognosis
chemical_list: D014408:Biomarkers, Tumor