title: A recently-discovered NMDA receptor gene, GRIN3B, is associated with duration mismatch negativity.
abstract: The study explored associations between mismatch negativity and N-methyl-d-aspartic acid receptor subunit genes, GRIN1, GRIN2B and GRIN3B in healthy subjects and schizophrenia. Nineteen single-nucleotide polymorphisms were genotyped in 138 schizophrenia patients and 103 healthy subjects. Rs2240158 of GRIN3B was significantly associated with mismatch negativity in healthy subjects.
authors.affiliation: Institute of Biomedical Engineering, National Taiwan University, No. 1, Sec. 1, Jen-Ai Road, Taipei City, Taiwan; Department of Psychiatry, National Taiwan University Hospital and College of Medicine, National Taiwan University, No. 1, Changde Street, Taipei City, Taiwan.
authors.forename: Yi-Ting
authors.initials: YT
authors.lastname: Lin
authors.affiliation: Institute of Biomedical Engineering, National Taiwan University, No. 1, Sec. 1, Jen-Ai Road, Taipei City, Taiwan; Department of Psychiatry, National Taiwan University Hospital and College of Medicine, National Taiwan University, No. 1, Changde Street, Taipei City, Taiwan; Neurobiology and Cognitive Science Center, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei City, Taiwan.
authors.forename: Ming H
authors.initials: MH
authors.lastname: Hsieh
authors.affiliation: Department of Psychiatry, National Taiwan University Hospital and College of Medicine, National Taiwan University, No. 1, Changde Street, Taipei City, Taiwan; Neurobiology and Cognitive Science Center, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei City, Taiwan.
authors.forename: Chen-Chung
authors.initials: CC
authors.lastname: Liu
authors.affiliation: Department of Psychiatry, National Taiwan University Hospital and College of Medicine, National Taiwan University, No. 1, Changde Street, Taipei City, Taiwan; Neurobiology and Cognitive Science Center, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei City, Taiwan.
authors.forename: Tzung-Jeng
authors.initials: TJ
authors.lastname: Hwang
authors.affiliation: Department of Psychiatry, National Taiwan University Hospital and College of Medicine, National Taiwan University, No. 1, Changde Street, Taipei City, Taiwan.
authors.forename: Yi-Ling
authors.initials: YL
authors.lastname: Chien
authors.affiliation: Department of Psychiatry, National Taiwan University Hospital and College of Medicine, National Taiwan University, No. 1, Changde Street, Taipei City, Taiwan; Neurobiology and Cognitive Science Center, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei City, Taiwan.
authors.forename: Hai-Gwo
authors.initials: HG
authors.lastname: Hwu
authors.affiliation: Department of Psychiatry, National Taiwan University Hospital and College of Medicine, National Taiwan University, No. 1, Changde Street, Taipei City, Taiwan; Neurobiology and Cognitive Science Center, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei City, Taiwan. Electronic address: cmliu1968@ntu.edu.tw.
authors.forename: Chih-Min
authors.initials: CM
authors.lastname: Liu
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D009419:Nerve Tissue Proteins / Q000235:genetics*; D011110:Polymorphism, Genetic; D020641:Polymorphism, Single Nucleotide; D016194:Receptors, N-Methyl-D-Aspartate / Q000235:genetics*; D012016:Reference Values; D012559:Schizophrenia / Q000235:genetics*
chemical_list: D009419:Nerve Tissue Proteins; D016194:Receptors, N-Methyl-D-Aspartate
keywords: Glutamate; Mismatch negativity; Schizophrenia