title: Comparison of brain 3.0-T with 1.5-T MRI in patients with multiple sclerosis: a 6-month follow-up study.
abstract: OBJECTIVE
  The 2010 revisions to the McDonald criteria for the diagnosis of multiple sclerosis (MS) were recently published. One objective of the revision was to simplify the MRI criteria. The MRI criteria do not specify magnetic field strength. We studied whether there was any difference in diagnosis between brain 3.0-T and 1.5-T MRI according to the 2010 revisions of the McDonald criteria.
  
  
  METHODS
  We prospectively studied brain 3.0-T and 1.5-T MRI in 22 patients with MS. 1.5-T MRI was performed 24h after 3.0-T MRI, and the scanning protocol included contiguous axial sections of T2-weighted images (T2WI), T1WI, and enhanced T1WI. These two different MRI and neurological assessments were scheduled to be repeated 3 and 6 months after study entry.
  
  
  RESULTS
  The regions where MS lesions were better visualized on 3.0-T MRI tended to be in deep white matter on T2WI. Dissemination of lesions in space and time was similar for 3.0-T and 1.5-T MRI.
  
  
  CONCLUSIONS
  Our study found no difference between brain 3.0-T and 1.5-T MRI. There was no apparent impact of brain 3.0-T MRI on the diagnosis of MS according to the 2010 version of the MRI criteria.
authors.affiliation: Department of Neurology, Nara Medical University, Kashihara, Nara, Japan. Electronic address: hk55@naramed-u.ac.jp.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kataoka
authors.affiliation: Department of Neurology, Nara Medical University, Kashihara, Nara, Japan.
authors.forename: Takao
authors.initials: T
authors.lastname: Kiriyama
authors.affiliation: Department of Radiology, Nara Medical University, Kashihara, Nara, Japan.
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Taoka
authors.affiliation: Department of Neurology, Heisei Memorial Hospital, Kashihara, Nara, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Oba
authors.affiliation: Department of Radiology, Heisei Memorial Hospital, Kashihara, Nara, Japan.
authors.forename: Megumi
authors.initials: M
authors.lastname: Takewa
authors.affiliation: Department of Neurology, Nara Medical University, Kashihara, Nara, Japan.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Eura
authors.affiliation: Department of Neurology, Nara Medical University, Kashihara, Nara, Japan.
authors.forename: Ryogo
authors.initials: R
authors.lastname: Syobatake
authors.affiliation: Department of Neurology, Nara Medical University, Kashihara, Nara, Japan.
authors.forename: Yasuyo
authors.initials: Y
authors.lastname: Kobayashi
authors.affiliation: Department of Neurology, Heisei Memorial Hospital, Kashihara, Nara, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kumazawa
authors.affiliation: Department of Neurology, Nara Medical University, Kashihara, Nara, Japan.
authors.forename: Tesseki
authors.initials: T
authors.lastname: Izumi
authors.affiliation: Department of Neurology, Nara Medical University, Kashihara, Nara, Japan.
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Furiya
authors.affiliation: Hospital Director, Heisei Memorial Hospital, Kashihara, Nara, Japan.
authors.forename: Nobufusa
authors.initials: N
authors.lastname: Aoyama
authors.affiliation: Department of Radiology, Nara Medical University, Kashihara, Nara, Japan.
authors.forename: Kimihiko
authors.initials: K
authors.lastname: Kichikawa
authors.affiliation: Department of Neurology, Nara Medical University, Kashihara, Nara, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ueno
mesh_terms: D000328:Adult; D000368:Aged; D001921:Brain / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000473:pathology*; D011446:Prospective Studies
keywords: 3Tesla; High-field MRI; MRI; McDonald criteria; Multiple sclerosis