title: Health-related quality of life in the first year after laparoscopic radical prostatectomy compared with open radical prostatectomy.
abstract: OBJECTIVE
  To assess health-related quality of life in the first year after laparoscopic radical prostatectomy compared with that after open radical prostatectomy.
  
  
  METHODS
  The subjects were 105 consecutive patients with localized prostate cancer treated with laparoscopic radical prostatectomy between January 2011 and June 2012. Health-related quality of life was evaluated using the International Prostate Symptom Score, Medical Outcome Study 8-Items Short Form Health Survey (SF-8) and Expanded Prostate Cancer Index Composite at baseline and 1, 3, 6 and 12 months after surgery. Comparisons were made with data for 107 consecutive patients treated with open radical prostatectomy between October 2005 and July 2007.
  
  
  RESULTS
  The International Prostate Symptom Score change was similar in each group. The laparoscopic radical prostatectomy group had a better baseline Medical Outcome Study 8-Items Short Form Health Survey mental component summary score and a better Medical Outcome Study 8-Items Short Form Health Survey physical component summary score at 1 month after surgery. In Expanded Prostate Cancer Index Composite, obstructive/irritative symptoms did not differ between the groups, but urinary incontinence was worse until 12 months after surgery and particularly severe after 1 month in the laparoscopic radical prostatectomy group. The rate of severe urinary incontinence was much higher in the laparoscopic radical prostatectomy group in the early period. Urinary bother was worse in the laparoscopic radical prostatectomy group at 1 and 3 months, but did not differ between the groups thereafter. Urinary function and bother were good after nerve sparing procedures and did not differ between the groups. Bowel and sexual function and bother were similar in the two groups.
  
  
  CONCLUSIONS
  Urinary function in the first year after laparoscopic radical prostatectomy is worse than that after open radical prostatectomy.
authors.affiliation: Department of Urology, National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan khashine@shikoku-cc.go.jp.
authors.forename: Katsuyoshi
authors.initials: K
authors.lastname: Hashine
authors.affiliation: Department of Urology, National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nakashima
authors.affiliation: Department of Urology, National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Iio
authors.affiliation: Department of Urology, National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan.
authors.forename: Yoshiteru
authors.initials: Y
authors.lastname: Ueno
authors.affiliation: Department of Urology, National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan.
authors.forename: Shinjiro
authors.initials: S
authors.lastname: Shimizu
authors.affiliation: Department of Urology, National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan.
authors.forename: Iku
authors.initials: I
authors.lastname: Ninomiya
mesh_terms: D000368:Aged; D044466:Asian People / Q000706:statistics & numerical data*; D006304:Health Status; D006801:Humans; D007564:Japan / Q000453:epidemiology; D010535:Laparoscopy / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011468:Prostatectomy / Q000009:adverse effects / Q000379:methods*; D011471:Prostatic Neoplasms / Q000601:surgery*; D011788:Quality of Life; D014549:Urinary Incontinence / Q000453:epidemiology / Q000209:etiology*
keywords: EPIC; SF-8; health-related quality of life; laparoscopic radical prostatectomy