title: Self-regulatory fatigue, quality of life, health behaviors, and coping in patients with hematologic malignancies.
abstract: BACKGROUND
  Self-regulatory fatigue may play an important role in a complex medical illness.
  
  
  OBJECTIVE
  Examine associations between self-regulatory fatigue, quality of life, and health behaviors in patients pre- (N = 213) and 1-year post-hematopoietic stem cell transplantation (HSCT; N = 140). Associations between self-regulatory fatigue and coping strategies pre-HSCT were also examined.
  
  
  METHODS
  Pre- and 1-year post-HSCT data collection. Hierarchical linear regression modeling.
  
  
  RESULTS
  Higher self-regulatory fatigue pre-HSCT associated with lower overall, physical, social, emotional, and functional quality of life pre- (p's < .001) and 1-year post-HSCT (p's < .01); lower physical activity pre-HSCT (p < .02) and post-HSCT (p < .03) and less healthy nutritional intake post-HSCT (p < .01); changes (i.e., decrease) in quality of life and healthy nutrition over the follow-up year; and use of avoidance coping strategies pre-HSCT (p's < .001).
  
  
  CONCLUSIONS
  This is the first study to show self-regulatory fatigue pre-HSCT relating to decreased quality of life and health behaviors, and predicting changes in these variables 1-year post-HSCT.
authors.affiliation: Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA, solbergnes@msn.com.
authors.forename: Lise
authors.initials: L
authors.lastname: Solberg Nes
authors.forename: Shawna L
authors.initials: SL
authors.lastname: Ehlers
authors.forename: Christi A
authors.initials: CA
authors.lastname: Patten
authors.forename: Dennis A
authors.initials: DA
authors.lastname: Gastineau
mesh_terms: D000223:Adaptation, Psychological / Q000502:physiology*; D000328:Adult; D000368:Aged; D005221:Fatigue / Q000523:psychology*; D005260:Female; D005500:Follow-Up Studies; D015438:Health Behavior; D019337:Hematologic Neoplasms / Q000523:psychology* / Q000628:therapy; D018380:Hematopoietic Stem Cell Transplantation / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life / Q000523:psychology*; D016896:Treatment Outcome; D055815:Young Adult