title: Time course and the recanalization rate of superficial vein thrombosis treated with low-molecular-weight heparin.
abstract: The aim of this study was to follow the thrombus progression and regression in superficial veins of lower limbs in patients with superficial vein thrombosis (SVT) treated with low-molecular-weight heparin. Patients (n = 68) with a first symptomatic SVT of the lower limbs received 2 different dosages of dalteparin. The primary outcome was a change in the diameter and length of thrombus in the affected veins. The regression of thrombus was not significantly different between the groups (P = .19). The reduction in the length of thrombus as well as thrombus diameter was significantly greater in females. At the end of the observation period, the length of thrombus in the distal part was more reduced than in the proximal segments. It seems that the dosage of anticoagulant drug does not have a significant impact on thrombus resolution.
authors.affiliation: Department of Vascular Disease, University Medical Centre Ljubljana, Ljubljana, Slovenia.
authors.forename: Ana
authors.initials: A
authors.lastname: Spirkoska
authors.affiliation: Department of Vascular Disease, University Medical Centre Ljubljana, Ljubljana, Slovenia.
authors.forename: Mateja Kaja
authors.initials: MK
authors.lastname: Jezovnik
authors.affiliation: Department of Vascular Disease, University Medical Centre Ljubljana, Ljubljana, Slovenia pavel.poredos@kclj.si.
authors.forename: Pavel
authors.initials: P
authors.lastname: Poredos
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000008:administration & dosage*; D017985:Dalteparin / Q000008:administration & dosage*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D035002:Lower Extremity / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D012501:Saphenous Vein / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000503:physiopathology; D012737:Sex Factors; D017524:Slovenia; D013997:Time Factors; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex; D014654:Vascular Patency / Q000187:drug effects; D020246:Venous Thrombosis / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D000925:Anticoagulants; D017985:Dalteparin
keywords: heparin; recanalization; superficial veins; thrombosis; ultrasound