title: [1483 cases of paternity test with STR loci mutation].
abstract: OBJECTIVE
  To observe and analyze the mutation phenomenon of 17 STR loci of PowerPlex 18D Kit in paternity test of Yunnan population.
  
  
  METHODS
  The DNA was extracted by Chelex-100 method. The PowerPlex 18D Kit was used to test 1,483 cases and their conclusions of paternity tests were verified.
  
  
  RESULTS
  In the 1,483 cases, 1,047 were parental triplet and 436 were uniparental diad. A total of 2,530 times of meiosis was observed. One STR locus mutation was observed in 24 cases. And 11 mutation loci were found in the 17 STR loci.
  
  
  CONCLUSIONS
  STR loci mutation is a common phenomenon. We should collect the data of STR loci mutation, choose other good polymorphism, low mutation rate of genetic markers, to ensure that the results are accurate and reliable.
authors.forename: Li
authors.initials: L
authors.lastname: Shuai
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.forename: Qiang
authors.initials: Q
authors.lastname: Jing
authors.forename: Bin
authors.initials: B
authors.lastname: Xu
authors.forename: Qin
authors.initials: Q
authors.lastname: Su
authors.forename: Yun-Juan
authors.initials: YJ
authors.lastname: Li
authors.forename: Hui
authors.initials: H
authors.lastname: Li
mesh_terms: D002681:China; D004247:DNA; D016172:DNA Fingerprinting; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers; D006801:Humans; D018895:Microsatellite Repeats; D009154:Mutation; D010334:Paternity; D011110:Polymorphism, Genetic
chemical_list: D005819:Genetic Markers; D004247:DNA