title: Acute renal failure according to the RIFLE and AKIN criteria: a multicenter study.
abstract: OBJECTIVE
  To determine the incidence of acute renal failure (ARF) in critically ill patients using the RIFLE and AKIN criteria.
  
  
  METHODS
  A prospective, multicenter observational study with a duration of one year from February 2010 was carried out. RIFLE and AKIN were employed using the urinary (UC) and creatinine criteria (CC) jointly and separately.
  
  
  METHODS
  Nine polyvalent Critical Care Units (CCUs) in Argentina.
  
  
  METHODS
  A total of 627 critical patients over 18 years of age were admitted to the CCU for more than 48h.
  
  
  METHODS
  inability to quantify diuresis, surgical instrumentation of the urinary tract, and need for renal support therapy (RST).
  
  
  METHODS
  Calculated hourly diuresis (CHD) was used to apply the UC.
  
  
  RESULTS
  The incidence of ARF was 69.4% and 51.8% according to RIFLE and AKIN, respectively. UC detected ARF in 59.5% of cases, while CC identified ARF in 34.7% (RIFLE) and 25.3% (AKIN). The mortality rate was 40.9% and 44.6% according to RIFLE and AKIN respectively, was significantly higher than in patients without ARF, and increased with disease severity (Data processing: Excel, SQL and SPSS. Levene test, comparison of means with Student t and chi-squared, with 95% confidence interval).
  
  
  CONCLUSIONS
  RIFLE identified more cases of ARF. UC proved more effective than CC. The presence of ARF and severity levels were correlated to mortality but not to days of stay in the CCU. Implementation of the unified CHD was useful for implementing UC and achieving comparable results.
authors.affiliation: Hospital E. Ferreyra de Necochea, Buenos Aires, Argentina. Electronic address: gasalg@hotmail.com.
authors.forename: G
authors.initials: G
authors.lastname: Salgado
authors.affiliation: Hospital E. Ferreyra de Necochea, Buenos Aires, Argentina.
authors.forename: M
authors.initials: M
authors.lastname: Landa
authors.affiliation: Sanatorio Otamendi, Ciudad Autónoma de Buenos Aires, Argentina.
authors.forename: D
authors.initials: D
authors.lastname: Masevicius
authors.affiliation: Hospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina.
authors.forename: S
authors.initials: S
authors.lastname: Gianassi
authors.affiliation: Hospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina.
authors.forename: J E
authors.initials: JE
authors.lastname: San-Román
authors.affiliation: Sanatorio Nuestra Señora del Rosario, Jujuy, Argentina.
authors.forename: L
authors.initials: L
authors.lastname: Silva
authors.affiliation: Clínica de los Virreyes, Ciudad Autónoma de Buenos Aires, Argentina.
authors.forename: M
authors.initials: M
authors.lastname: Gimenez
authors.affiliation: Hospital Pablo Soria, Jujuy, Argentina.
authors.forename: O
authors.initials: O
authors.lastname: Tejerina
authors.affiliation: Hospital Ramón Santamarina de Tandil, Buenos Aires, Argentina.
authors.forename: P
authors.initials: P
authors.lastname: Díaz-Cisneros
authors.affiliation: Hospital Leónidas Lucero de Bahía Blanca, Buenos Aires, Argentina.
authors.forename: F
authors.initials: F
authors.lastname: Ciccioli
authors.affiliation: Hospital E. Ferreyra de Necochea, Buenos Aires, Argentina.
authors.forename: J L
authors.initials: JL
authors.lastname: do Pico
mesh_terms: D058186:Acute Kidney Injury / Q000453:epidemiology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016638:Critical Illness; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D055815:Young Adult
keywords: AKIN; Acute renal failure; Criterio creatinina; Criterio urinario; Insuficiencia renal aguda; RIFLE