title: A 2-year follow-up study of discharged psychiatric patients with bipolar disorder.
abstract: This study investigated medication compliance, disease recurrence and the recovery of social function in discharged psychiatric patients with bipolar disorder. A 2-year follow-up was conducted on all patients with bipolar disorder, who were hospitalized in our psychiatric department between June 2010 and May 2011. Risk factors for recurrence were analyzed based on a self-designed questionnaire. Of the 252 patients in the study, 210 had complete information (83.3%) for the 2-year follow-up: 170 cases of bipolar I disorder and 40 cases of bipolar II disorder. The 1-year and 2-year full-compliance rates were 41.0% and 35.7%, respectively. The 1-year and 2-year recurrence rates were 42.4% and 61.0%, respectively. Statistically significant differences in rates were found between the bipolar subtypes for 1-year full compliance, 1-year non-compliance, 2-year recurrence, and 2-year readmission. Logistic regression identified different sets of independent variables that were risk factors for recurrence, and protective factors for recurrence at 1 year and 2 years after hospital discharge. The results of the follow-up indicated that the situation of patients with bipolar disorder after discharge is not optimistic, because of high recurrence rates, high non-compliance rates and low recovery rates. Clinical and social experts should pay more attention to the situation.
authors.affiliation: Department of Psychiatry, WuZhongpei Memorial Hospital, No. 3 Jianmin Road, Daliang Town, Shunde District of Foshan City, Guangdong 528300, China.
authors.forename: Chunyang
authors.initials: C
authors.lastname: Li
authors.affiliation: Department of Psychiatry, WuZhongpei Memorial Hospital, No. 3 Jianmin Road, Daliang Town, Shunde District of Foshan City, Guangdong 528300, China. Electronic address: chenchaowzp@163.com.
authors.forename: Chao
authors.initials: C
authors.lastname: Chen
authors.affiliation: Department of Psychiatry, WuZhongpei Memorial Hospital, No. 3 Jianmin Road, Daliang Town, Shunde District of Foshan City, Guangdong 528300, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Qiu
authors.affiliation: Department of Psychiatry, WuZhongpei Memorial Hospital, No. 3 Jianmin Road, Daliang Town, Shunde District of Foshan City, Guangdong 528300, China.
authors.forename: Guang
authors.initials: G
authors.lastname: Yang
mesh_terms: D000328:Adult; D018692:Antimanic Agents / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000188:drug therapy / Q000523:psychology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D010351:Patient Discharge; D012008:Recurrence; D012307:Risk Factors; D012917:Social Adjustment
chemical_list: D018692:Antimanic Agents
keywords: Bipolar disorder; Medication compliance; Recurrence