title: [Clinical analysis of the correlation factors of chronic sinusitis osteitis].
abstract: OBJECTIVE
  To analyse the severity of chronic sinusitis osteitis and the correlation factors by global osteitis scoring scale(GOSS).
  
  
  METHODS
  Three hundreds and thirty-four patients with chronic rhinosinusitis with or without nasal polyps(CRSwNP/CRSsNP) were enrolled prospectively in a large tertiary referral center. Preoperative sinus CT was analysed by PHILIPS MxLiteView software.Using grading and classification of GOSS, the association between GOSS and gender, age, smoking, CRS course, asthma, skin prick test(SPT), aspirin sensitive asthma (ASA), nasal polyp, Lund-Mackay, Lund-Kennedy, the number of previous sinus surgeries was examined.Finally a marker factors of severity of CRS osteitis was concluded.
  
  
  RESULTS
  There was no association between CRS osteitis and gender(P = 0.542), age(P = 0.092), smoking(P = 0.695), SPT(P = 0.182). Multiple liner regression analysis showed that there was no association between CRS osteitis and nasal polyps, ASA and asthma (all P > 0.05). The severity of CRS osteitis was correlated with the number of previous sinus surgeries, Lund-Mackay scores, Lund-Kennedy scores, CRS course (r1 = 0.528, r2 = 0.170, r3 = 0.193, r4 = 0.146, respectively, all P < 0.01).
  
  
  CONCLUSIONS
  Osteitis is an important reason of refractory chronic rhinosinusitis. The number of previous sinus surgeries can be used as an important marker for the severity of the osteitis.
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery,Daxing Hospial, Capital Medical University,Beijing 102600, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Cheng
authors.forename: Zhenxiao
authors.initials: Z
authors.lastname: Huang
authors.forename: Qian
authors.initials: Q
authors.lastname: Huang
authors.forename: Chengshuo
authors.initials: C
authors.lastname: Wang
authors.forename: Shunjiu
authors.initials: S
authors.lastname: Cui
authors.forename: Feng
authors.initials: F
authors.lastname: Lin
authors.forename: Yan
authors.initials: Y
authors.lastname: Sun
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otorhinolaryngology Head and Neck Surgery, Ministry of Education (Capital Medical University), Beijing 100730, China. Email: entzhou@263.net.
authors.forename: Bing
authors.initials: B
authors.lastname: Zhou
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010000:Osteitis / Q000209:etiology*; D012220:Rhinitis / Q000209:etiology*; D012720:Severity of Illness Index; D012852:Sinusitis / Q000209:etiology*; D055815:Young Adult