title: Chemoselective N-heterocyclic carbene-catalyzed cross-benzoin reactions: importance of the fused ring in triazolium salts.
abstract: Morpholinone- and piperidinone-derived triazolium salts are shown to catalyze highly chemoselective cross-benzoin reactions between aliphatic and aromatic aldehydes. The reaction scope includes ortho-, meta-, and para-substituted benzaldehyde derivatives with a range of electron-donating and -withdrawing groups as well as branched and unbranched aliphatic aldehydes. Catalytic loadings as low as 5 mol % give excellent yields in these reactions (up to 99%).
authors.affiliation: Department of Chemistry, University of Saskatchewan , 110 Science Place, Saskatoon, Saskatchewan S7N 5C9, Canada.
authors.forename: Steven M
authors.initials: SM
authors.lastname: Langdon
authors.forename: Myron M D
authors.initials: MM
authors.lastname: Wilde
authors.forename: Karen
authors.initials: K
authors.lastname: Thai
authors.forename: Michel
authors.initials: M
authors.lastname: Gravel