title: Hypereosinophilic Syndrome Leading to Severe Right-Sided Heart Failure in a Patient with Ebstein's Anomaly.
abstract: A 36-year-old male with mild Ebstein's anomaly developed severe right-sided heart failure, following a 5-year-long course of hypereosinophilic syndrome. No regular followups had been done, during the years of antineoplastic therapy. A year after being cured from the hypereosinophilic syndrome, the patient developed right-sided heart failure symptoms and was found to have excessive fibrosis of the right ventricular endocardium and free tricuspid regurgitation. The findings were compatible with substantial scarring of the endocardium caused by the hypereosinophilic syndrome. Over a few years, the patient deteriorated significantly and was finally offered a heart transplant. Examination of the explanted heart revealed severe fibrosis of the right ventricle and almost complete sparing of the left.
authors.affiliation: Department of Cardiology, Aarhus University Hospital, 8200 Aarhus, Denmark.
authors.forename: Joas John
authors.initials: JJ
authors.lastname: Kyabonaki
authors.affiliation: Department of Cardiology, Aarhus University Hospital, 8200 Aarhus, Denmark.
authors.forename: Bjarne Linde
authors.initials: BL
authors.lastname: Nørgaard
authors.affiliation: Department of Pathology, Aarhus University Hospital, 8000 Aarhus, Denmark.
authors.forename: Søren
authors.initials: S
authors.lastname: Høyer
authors.affiliation: Department of Cardiology, Aarhus University Hospital, 8200 Aarhus, Denmark.
authors.forename: Niels Holmark
authors.initials: NH
authors.lastname: Andersen