title: Small G Proteins Dexras1 and RHES and Their Role in Pathophysiological Processes.
abstract: Dexras1 and RHES, monomeric G proteins, are members of small GTPase family that are involved in modulation of pathophysiological processes. Dexras1 and RHES levels are modulated by hormones and Dexras1 expression undergoes circadian fluctuations. Both these GTPases are capable of modulating calcium ion channels which in turn can potentially modulate neurosecretion/hormonal release. These two GTPases have been reported to prevent the aberrant cell growth and induce apoptosis in cell lines. Present review focuses on role of these two monomeric GTPases and summarizes their role in pathophysiological processes.
authors.affiliation: Department of Biotechnology, Graphic Era University, Dehradun, Uttarakhand 248002, India.
authors.forename: Ashish
authors.initials: A
authors.lastname: Thapliyal
authors.affiliation: Department of Biotechnology, Graphic Era University, Dehradun, Uttarakhand 248002, India.
authors.forename: Rashmi
authors.initials: R
authors.lastname: Verma
authors.affiliation: Department of Biotechnology, Graphic Era University, Dehradun, Uttarakhand 248002, India.
authors.forename: Navin
authors.identifier: 0000-0003-3531-7414
authors.initials: N
authors.lastname: Kumar