title: Usefulness of lipid ratios and atherogenic index of plasma in obese Moroccan women with or without metabolic syndrome.
abstract: OBJECTIVE
  Our study aimed to study the impact of obesity and metabolic syndrome (MetS) on lipoprotein profiles and cardiovascular risk through lipid ratios and atherogenic index of plasma (AIP) in Moroccan women.
  
  
  METHODS
  Our study included 240 Moroccan women, aged 53.31 +/- 8.51 years, divided into three groups: controls (group 1, n = 80), obese without MetS (group 2, n = 80) and obese with MetS (group 3, n = 80). Anthropometric and lipid measurements were taken and specific lipid ratios assessed, as well as Non-HDL cholesterol (Non-HDL-C) and atherogenic index of plasma (ALP).
  
  
  RESULTS
  Group 2 presented similar lipoprotein profiles compared with group 1. Group 3 had higher triglyceride (TG) levels than group 1, which, in turn, increased HDL and AIP values. Dyslipidemia in group 3 was demonstrated by higher TG levels, lipid ratios and AIP and lower HDL-C levels compared with group 2. All of these abnormalities are responsible for elevations of risks of cardiovascular diseases. Closer associations were found between cardiovascular risk and lipid ratios and AIP than lipids alone.
  
  
  CONCLUSIONS
  Our study confirms that MetS affects the serum lipoprotein profile of obese women. Lipid ratios, non HDL-C and AIP remain useful tools for the diagnosis and prognosis of cardiovascular disease by their associations with lipid parameters and their high predictive values.
authors.forename: Fadwa
authors.initials: F
authors.lastname: Essiarab
authors.forename: Hassan
authors.initials: H
authors.lastname: Taki
authors.forename: Halima
authors.initials: H
authors.lastname: Lebrazi
authors.forename: Maati
authors.initials: M
authors.lastname: Sabri
authors.forename: Rachid
authors.initials: R
authors.lastname: Saïle
mesh_terms: D000328:Adult; D000368:Aged; D050197:Atherosclerosis / Q000097:blood* / Q000473:pathology; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D024821:Metabolic Syndrome / Q000097:blood*; D008875:Middle Aged; D009018:Morocco; D009765:Obesity / Q000097:blood* / Q000473:pathology; D016017:Odds Ratio
chemical_list: D008055:Lipids