title: Single-layered graphitic-C(3)N(4) quantum dots for two-photon fluorescence imaging of cellular nucleus.
abstract: A promising, safe, and economic fluorescent probe, g-C3 N4 single-layered QDs, is introduced for two-photon fluorescence imaging of the cellular nucleus for the first time. The large two-photon absorption cross section, the high photostability, good biocompatibility and non-toxicity, negligible photothermal effect, and specific interaction with DNA render the single-layered g-C3 N4 QDs as a promising candidate for in vivo and in vitro two-photon fluorescence imaging and further biomedical applications.
authors.affiliation: Hefei National Laboratory for Physical Sciences at the Microscale, Collaborative Innovation Center of Chemistry for Energy Materials, University of Science and Technology of China, Hefei, Anhui, 230026, P. R. China.
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Zhang
authors.forename: Hongxia
authors.initials: H
authors.lastname: Wang
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Qiong
authors.initials: Q
authors.lastname: Zhang
authors.forename: Junfeng
authors.initials: J
authors.lastname: Xie
authors.forename: Yupeng
authors.initials: Y
authors.lastname: Tian
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.forename: Yi
authors.initials: Y
authors.lastname: Xie
mesh_terms: D002467:Cell Nucleus / Q000378:metabolism*; D005456:Fluorescent Dyes; D006108:Graphite; D057809:HEK293 Cells; D056945:Hep G2 Cells; D006801:Humans; D046529:Microscopy, Electron, Transmission; D036641:Microscopy, Fluorescence, Multiphoton; D009570:Nitriles; D010316:Particle Size; D045663:Quantum Dots / Q000737:chemistry* / Q000648:ultrastructure
chemical_list: D005456:Fluorescent Dyes; D009570:Nitriles; C011206:cyanogen; D006108:Graphite
keywords: bioimaging; cellular nucleus; graphitic-C3N4; single-layered nanosheet; two-photon fluorescence