title: Incisional surgical site infection after elective open surgery for colorectal cancer.
abstract: BACKGROUND
  The purpose of this study was to clarify the incidence and risk factors for incisional surgical site infections (SSI) in patients undergoing elective open surgery for colorectal cancer.
  
  
  METHODS
  We conducted prospective surveillance of incisional SSI after elective colorectal resections performed by a single surgeon for a 1-year period. Variables associated with infection, as identified in the literature, were collected and statistically analyzed for their association with incisional SSI development.
  
  
  RESULTS
  A total of 224 patients were identified for evaluation. The mean patient age was 67 years, and 120 (55%) were male. Thirty-three (14.7%) patients were diagnosed with incisional SSI. Multivariate analysis suggested that incisional SSI was independently associated with TNM stages III and IV (odds ratio [OR], 2.4) and intraoperative hypotension (OR, 3.4).
  
  
  CONCLUSIONS
  The incidence of incisional SSI in our cohort was well within values generally reported in the literature. Our data suggest the importance of the maintenance of intraoperative normotension to reduce the development of incisional SSI.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo 060-8638, Japan.
authors.forename: Kosuke
authors.identifier: 0000-0002-6068-7276
authors.initials: K
authors.lastname: Ishikawa
authors.affiliation: Department of Surgery, Keiyukai Sapporo Hospital, Kita 1-1, Hondori 14, Shiroishi-ku, Sapporo 003-0027, Japan.
authors.forename: Takaya
authors.initials: T
authors.lastname: Kusumi
authors.affiliation: Department of Surgery, Keiyukai Sapporo Hospital, Kita 1-1, Hondori 14, Shiroishi-ku, Sapporo 003-0027, Japan.
authors.forename: Masao
authors.initials: M
authors.lastname: Hosokawa
authors.affiliation: Department of Surgery, Keiyukai Sapporo Hospital, Kita 1-1, Hondori 14, Shiroishi-ku, Sapporo 003-0027, Japan.
authors.forename: Yasunori
authors.identifier: 0000-0002-6068-1421
authors.initials: Y
authors.lastname: Nishida
authors.affiliation: Department of Surgery, Keiyukai Sapporo Hospital, Kita 1-1, Hondori 14, Shiroishi-ku, Sapporo 003-0027, Japan.
authors.forename: Sosuke
authors.initials: S
authors.lastname: Sumikawa
authors.affiliation: Department of Plastic and Reconstructive Surgery, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo 060-8638, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Furukawa
mesh_terms: D000328:Adult; D000368:Aged; D019072:Antibiotic Prophylaxis; D015179:Colorectal Neoplasms / Q000601:surgery*; D017558:Elective Surgical Procedures / Q000009:adverse effects; D005260:Female; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus; D008875:Middle Aged; D011446:Prospective Studies; D011552:Pseudomonas Infections / Q000209:etiology*; D011550:Pseudomonas aeruginosa; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000209:etiology*; D013212:Staphylococcus epidermidis; D013530:Surgical Wound Infection / Q000209:etiology*