title: Malignant Triton Tumor of the Sciatic Nerve as a Secondary Malignancy after Extended Field Radiotherapy and Chemotherapy of Hodgkin's Disease.
abstract: Late effects of therapy for Hodgkin's disease include secondary malignancies like leukemia, lymphoma or solid tumors developing after long periods of latency. Ionizing radiation often causes the last group. The highest risks have been described for induced breast and lung cancers. We are the first to report a malignant triton tumor (MTT) as a secondary malignancy after radiotherapy and chemotherapy for Hodgkin's lymphoma. MTT is a very rare subtype of malignant peripheral nerve sheath tumors with rhabdomyoblastic differentiation and an aggressive course of disease.
authors.affiliation: Zentrum für Strahlentherapie und Radioonkologie, Bremen/Westerstede, Kiel, Germany ; Klinik für Strahlentherapie, Karl-Lennert-Krebscentrum, Universität Kiel, Kiel, Germany.
authors.forename: Mirko
authors.initials: M
authors.lastname: Nitsche
authors.affiliation: Zentrum für Strahlentherapie und Radioonkologie, Bremen/Westerstede, Kiel, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Reible
authors.affiliation: Abteilung für Hämatologie und internistische Onkologie, DIAKO Bremen, Germany.
authors.forename: Karl-Heinz
authors.initials: KH
authors.lastname: Pflüger
authors.affiliation: Institut für Neuropathologie, Klinikum Bremen Mitte, Bremen, Germany.
authors.forename: Markus
authors.initials: M
authors.lastname: Bergmann
authors.affiliation: Zentrum für Strahlentherapie und Radioonkologie, Bremen/Westerstede, Kiel, Germany ; Abteilung Strahlentherapie und spezielle Onkologie, Medizinische Hochschule Hannover, Hannover, Germany.
authors.forename: Robert Michael
authors.initials: RM
authors.lastname: Hermann
keywords: Hodgkin's disease; Radiotherapy; Second malignancy; Triton tumor