title: Targeting the BET family for the treatment of leukemia.
authors.affiliation: Pharmaceutical Bioinformatics, Institute of Pharmaceutical Sciences, Albert-Ludwigs-University, Hermann-Herder-Str. 9, D-79104 Freiburg, Germany.
authors.forename: Xavier
authors.initials: X
authors.lastname: Lucas
authors.forename: Stefan
authors.initials: S
authors.lastname: Günther
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001381:Azepines / Q000627:therapeutic use; D001569:Benzodiazepines / Q000627:therapeutic use; D018797:Cell Cycle Proteins; D049109:Cell Proliferation / Q000187:drug effects; D015870:Gene Expression / Q000187:drug effects; D006801:Humans; D007938:Leukemia / Q000188:drug therapy* / Q000235:genetics; D009687:Nuclear Proteins / Q000037:antagonists & inhibitors* / Q000235:genetics; D017346:Protein Serine-Threonine Kinases / Q000037:antagonists & inhibitors*; D011799:Quinazolines / Q000627:therapeutic use; D052999:Quinazolinones; D016601:RNA-Binding Proteins / Q000037:antagonists & inhibitors*; D014157:Transcription Factors / Q000037:antagonists & inhibitors*; D014230:Triazoles / Q000627:therapeutic use; D000092468:Bromodomain Containing Proteins
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000970:Antineoplastic Agents; D001381:Azepines; D001569:Benzodiazepines; D018797:Cell Cycle Proteins; D009687:Nuclear Proteins; D017346:Protein Serine-Threonine Kinases; D011799:Quinazolines; D052999:Quinazolinones; D016601:RNA-Binding Proteins; D014157:Transcription Factors; D014230:Triazoles; C561695:(+)-JQ1 compound; C098415:BRD2 protein, human; D000092468:Bromodomain Containing Proteins; C109106:BRD3 protein, human; C441289:BRD4 protein, human; C109570:BRDT protein, human; C554645:molibresib; C000628794:apabetalone