title: Value of a new stick-type rapid urine test for the diagnosis of Helicobacter pylori infection in the Vietnamese population.
abstract: OBJECTIVE
  To assess the value of a new test for the diagnosis of Helicobacter pylori (H. pylori) infection, Rapirun H. pylori Antibody Stick (Rapirun Stick), in a Vietnamese population.
  
  
  METHODS
  Eligible patients without previous history of H. pylori eradication were recruited. Rapid urease test (RUT) and histologic examination were used to diagnose the H. pylori infection. Patients were considered H. pylori positive when the RUT results were positive and/or the bacteria were detected histologically. Rapirun Stick tests were performed using urine samples, and the results were compared with the other 2 methods.
  
  
  RESULTS
  We enrolled 200 patients with a mean age of 36 (range, 18-76) years. There were 116 females and 84 males. Of the 200 patients, 111 (55.5%) were diagnosed as being H. pylori positive. The sensitivity, specificity, and accuracy of the Stick test were 84.7%, 89.9%, and 87.0%, respectively. There were 17 (8.5%) false-negative patients and 9 (4.5%) false-positive patients.
  
  
  CONCLUSIONS
  The Rapirun Stick test has high sensitivity, specificity, and accuracy for the diagnosis of H. pylori infection in the Vietnamese population. The test can be clinically applied in Vietnamese populations.
authors.affiliation: Duc T Quach, Quang D Le, Nhu HT Vu, Department of Endoscopy, University Medical Center, Ho Chi Minh 70000, Vietnam.
authors.forename: Duc T
authors.initials: DT
authors.lastname: Quach
authors.affiliation: Duc T Quach, Quang D Le, Nhu HT Vu, Department of Endoscopy, University Medical Center, Ho Chi Minh 70000, Vietnam.
authors.forename: Toru
authors.initials: T
authors.lastname: Hiyama
authors.affiliation: Duc T Quach, Quang D Le, Nhu HT Vu, Department of Endoscopy, University Medical Center, Ho Chi Minh 70000, Vietnam.
authors.forename: Fumio
authors.initials: F
authors.lastname: Shimamoto
authors.affiliation: Duc T Quach, Quang D Le, Nhu HT Vu, Department of Endoscopy, University Medical Center, Ho Chi Minh 70000, Vietnam.
authors.forename: Quang D
authors.initials: QD
authors.lastname: Le
authors.affiliation: Duc T Quach, Quang D Le, Nhu HT Vu, Department of Endoscopy, University Medical Center, Ho Chi Minh 70000, Vietnam.
authors.forename: Linh X
authors.initials: LX
authors.lastname: Ho
authors.affiliation: Duc T Quach, Quang D Le, Nhu HT Vu, Department of Endoscopy, University Medical Center, Ho Chi Minh 70000, Vietnam.
authors.forename: Nhu Ht
authors.initials: NH
authors.lastname: Vu
authors.affiliation: Duc T Quach, Quang D Le, Nhu HT Vu, Department of Endoscopy, University Medical Center, Ho Chi Minh 70000, Vietnam.
authors.forename: Masaharu
authors.initials: M
authors.lastname: Yoshihara
authors.affiliation: Duc T Quach, Quang D Le, Nhu HT Vu, Department of Endoscopy, University Medical Center, Ho Chi Minh 70000, Vietnam.
authors.forename: Naomi
authors.initials: N
authors.lastname: Uemura
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000652:urine*; D015415:Biomarkers / Q000652:urine; D001706:Biopsy; D004797:Enzyme-Linked Immunosorbent Assay / Q000295:instrumentation*; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D005773:Gastroscopy; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology / Q000652:urine; D016480:Helicobacter pylori / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011934:Reagent Strips; D015203:Reproducibility of Results; D016482:Urinalysis / Q000295:instrumentation*; D014744:Vietnam; D055815:Young Adult
chemical_list: D000907:Antibodies, Bacterial; D015415:Biomarkers; D011934:Reagent Strips
keywords: Helicobacter pylori; Rapid urease test; Rapirun® Stick; Urine test; Vietnamese