title: On-line in-tube solid phase microextraction-capillary liquid chromatography method for monitoring degradation products of di-(2-ethylhexyl) phthalate in waters.
abstract: The main di-(2-ethylhexyl) phthalate (DEHP) degradation products, (2-ethylhexyl) phthalate (MEHP), diethyl phthalate (DEP) and dibutyl phthalate (DBP), have been tested. The proposed cost-effective method combines on-line, in-tube solid-phase micro extraction (IT-SPME) in in-valve configuration and capillary liquid chromatography with UV diode array detection (Cap-LC-DAD). Acidification of the samples at pH 3 improved markedly the estimation of MEHP. Aliquots of 4mL of acidified water samples were directly processed. After sample loading, the analytes were desorbed with the mobile-phase and transferred to the monolithic capillary column. Satisfactory linearity and precision, absence of matrix effect and suitable limits of detection (LODs): 0.005, 0.1, 0.1 and 1.5μg/L for MEHP, DEP, DEHP and DBP, respectively have been achieved. The main advantages are speed and the reduction of background signal by minimizing sample preparation. Real water samples have been analyzed.
authors.affiliation: Departamento de Química Analítica, Facultad de Química, Universidad de Valencia, Dr. Moliner 50, 46100 Burjassot, Valencia, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Jornet-Martínez
authors.affiliation: Departamento de Química Analítica, Facultad de Química, Universidad de Valencia, Dr. Moliner 50, 46100 Burjassot, Valencia, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Muñoz-Ortuño
authors.affiliation: Departamento de Química Analítica, Facultad de Química, Universidad de Valencia, Dr. Moliner 50, 46100 Burjassot, Valencia, Spain.
authors.forename: Y
authors.initials: Y
authors.lastname: Moliner-Martínez
authors.affiliation: Departamento de Química Analítica, Facultad de Química, Universidad de Valencia, Dr. Moliner 50, 46100 Burjassot, Valencia, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Herráez-Hernández
authors.affiliation: Departamento de Química Analítica, Facultad de Química, Universidad de Valencia, Dr. Moliner 50, 46100 Burjassot, Valencia, Spain. Electronic address: pilar.campins@uv.es.
authors.forename: P
authors.initials: P
authors.lastname: Campíns-Falcó
mesh_terms: D002853:Chromatography, Liquid / Q000379:methods; D003993:Dibutyl Phthalate / Q000032:analysis*; D004051:Diethylhexyl Phthalate / Q000031:analogs & derivatives / Q000032:analysis*; D010795:Phthalic Acids / Q000032:analysis*; D010968:Plasticizers / Q000032:analysis*; D052617:Solid Phase Microextraction; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D010795:Phthalic Acids; D010968:Plasticizers; D014874:Water Pollutants, Chemical; D003993:Dibutyl Phthalate; D004051:Diethylhexyl Phthalate; C016599:mono-(2-ethylhexyl)phthalate; C007379:diethyl phthalate
keywords: Capillary chromatography; In-tube solid-phase microextraction (IT-SPME); Phthalates degradation; Water analysis