title: Copper-catalyzed oxidative cyclization of 1,5-enynes with concomitant C-C bond cleavage: an unexpected access to 3-formyl-1-indenone derivatives.
abstract: A Cu(0)/Selectfluor system-mediated oxidative cyclization of 1,5-enynes with concomitant C-C bond cleavage to access 3-formyl-1-indenone derivatives is described. Preliminary mechanistic investigations disclosed that the C-C bond cleavage involved a novel water-participated oxygen-insertion β-carbon elimination through double oxycuprations.
authors.affiliation: State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, Key Laboratory of Green Pesticides and Cleaner Production Technology of Zhejiang Province, Zhejiang University of Technology , Hangzhou 310014, People's Republic of China.
authors.forename: Jian
authors.initials: J
authors.lastname: Zhang
authors.forename: Degui
authors.initials: D
authors.lastname: Wu
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Chen
authors.forename: Yunkui
authors.initials: Y
authors.lastname: Liu
authors.forename: Zhenyuan
authors.initials: Z
authors.lastname: Xu