title: Endoscopic transsphenoidal treatment of a prolactinoma patient with brain and optic chiasmal herniations.
abstract: Bromocriptine has been the most widely used and effective agent to treat macroprolactinoma, and chiasmal herniation in a macroprolactinoma patient following the treatment with bromocriptine is a well-recognized complication. However, herniation of the inferior mesial frontal lobe into the sella has been rarely reported. The present clinical report is the second radiographic demonstration of herniation of the inferior mesial frontal lobe into the sella. After the treatment with transsphenoidal endoscopic chiasmopexy, the patient's visual disturbance improved dramatically. We suggest that transsphenoidal endoscopic chiasmopexy is an effective treatment option for the prolactinoma patient with brain and chiasmal herniations following the treatment with bromocriptine.
authors.affiliation: From the *Department of Neurosurgery, Shanghai Fengxian District Central Hospital, Shanghai Jiao Tong University Affiliated Sixth People's Hospital South Campus; and †Department of Neurosurgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Zhang
authors.forename: Liemei
authors.initials: L
authors.lastname: Guo
authors.forename: Jianwei
authors.initials: J
authors.lastname: Ge
authors.forename: Yongming
authors.initials: Y
authors.lastname: Qiu
mesh_terms: D001971:Bromocriptine / Q000009:adverse effects; D018491:Dopamine Agonists / Q000009:adverse effects; D004724:Endoscopy / Q000379:methods; D005260:Female; D006547:Hernia / Q000209:etiology*; D059685:Herniorrhaphy / Q000379:methods*; D006801:Humans; D019635:Neurosurgical Procedures / Q000379:methods*; D009897:Optic Chiasm / Q000601:surgery*; D010911:Pituitary Neoplasms / Q000601:surgery; D015175:Prolactinoma / Q000188:drug therapy*; D012658:Sella Turcica; D013100:Sphenoid Bone / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D018491:Dopamine Agonists; D001971:Bromocriptine