title: Intraabdominal hypertention--predisposing factor for visceral alterations and abdominal compartment syndrome.
abstract: Compartment syndrome (CS) is a condition in which increased pressure in a confined anatomical space adversely affects the function and viability of the tissues therein.
  
  
  OBJECTIVE
  The aim of the following research is to detect the influence of the intraabdominal hypertension (IAH) as an often met condition in visceral surgery on the organs in the abdominal cavity and outside it and on musculus rectus abdominis.
  
  
  METHODS
  We used adult Wister rats for creating an experimental model of IAH, using our own experimental method with many advantages.
  
  
  RESULTS
  We found expressed alterations in the organs of the group with IAH = 25 mmHg. Morphological changes were found in lung, small intestine, large intestine, stomach, liver, kidneys, spleen and in musculus rectus abdominis In the sham group without IAH we did not find any pathomorphological alterations. CONCLUSIONS. IAH, which is considered as a predictor of ACS and MOF, lasting for only 60 min. and level of = 25 mmHg causes heavy visceral alterations within, and also outside the abdominal cavity, and of the abdominal wall.
authors.forename: G
authors.initials: G
authors.lastname: Deenichin
authors.forename: R
authors.initials: R
authors.lastname: Dimov
mesh_terms: D034841:Abdominal Cavity / Q000473:pathology; D034861:Abdominal Wall / Q000473:pathology; D000818:Animals; D006801:Humans; D007422:Intestines / Q000473:pathology; D059325:Intra-Abdominal Hypertension / Q000150:complications* / Q000473:pathology*; D007668:Kidney / Q000473:pathology; D008099:Liver / Q000473:pathology; D008168:Lung / Q000473:pathology; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D017568:Rectus Abdominis / Q000473:pathology; D013154:Spleen / Q000473:pathology; D013270:Stomach / Q000473:pathology