title: Evaluation of anti-Müllerian hormone in a dog with a Sertoli cell tumour.
abstract: BACKGROUND
  Testicular tumours are common in elderly male dogs, and Sertoli cell tumours (SCTs) are among the most common. An increase in blood estradiol concentration is often seen in canine SCTs, but such measurements do not necessarily correlate with the clinical signs.
  
  
  METHODS
  A 6-year-old male Pembroke Welsh corgi was referred for nonpruritic alopecia. Clinical examination revealed cryptorchidism of the right testicle, and blood tests showed an increased estradiol concentration. The cryptorchid testis was removed by laparotomy, and SCT was diagnosed histologically. An enzyme-linked immunosorbent assay kit designed to measure human anti-Müllerian hormone (AMH) revealed a very high preoperative serum AMH concentration, which decreased after surgery. The serum AMH concentrations of two intact healthy control male dogs were lower than that of the dog with the SCT before treatment but higher than thoseof two healthy castrated male dogs.
  
  
  CONCLUSIONS
  Canine serum AMH concentrations, as measured by a human AMH enzyme-linked immunosorbent assay, may be useful as a marker for canine SCT.
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Ano
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Hidaka
authors.forename: Hiromu
authors.initials: H
authors.lastname: Katamoto
mesh_terms: D000505:Alopecia / Q000209:etiology / Q000662:veterinary; D000818:Animals; D054304:Anti-Mullerian Hormone / Q000097:blood / Q000378:metabolism*; D014408:Biomarkers, Tumor / Q000097:blood / Q000378:metabolism*; D003456:Cryptorchidism / Q000150:complications / Q000662:veterinary; D004283:Dog Diseases / Q000097:blood / Q000209:etiology / Q000378:metabolism*; D004285:Dogs; D008297:Male; D012707:Sertoli Cell Tumor / Q000150:complications / Q000378:metabolism / Q000662:veterinary*; D013736:Testicular Neoplasms / Q000150:complications / Q000378:metabolism / Q000662:veterinary*
chemical_list: D014408:Biomarkers, Tumor; D054304:Anti-Mullerian Hormone