title: Pathology of US porcine epidemic diarrhea virus strain PC21A in gnotobiotic pigs.
abstract: To understand the progression of porcine epidemic diarrhea virus infection, we inoculated gnotobiotic pigs with a newly emerged US strain, PC21A, of the virus. At 24–48 hours postinoculation, the pigs exhibited severe diarrhea and vomiting, fecal shedding, viremia, and severe atrophic enteritis. These findings confirm that strain PC21A is highly enteropathogenic.
authors.forename: Kwonil
authors.initials: K
authors.lastname: Jung
authors.forename: Qiuhong
authors.initials: Q
authors.lastname: Wang
authors.forename: Kelly A
authors.initials: KA
authors.lastname: Scheuer
authors.forename: Zhongyan
authors.initials: Z
authors.lastname: Lu
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Linda J
authors.initials: LJ
authors.lastname: Saif
mesh_terms: D000818:Animals; D018352:Coronavirus Infections / Q000473:pathology* / Q000821:virology*; D003967:Diarrhea / Q000821:virology; D005243:Feces / Q000821:virology; D005856:Germ-Free Life; D053485:Porcine epidemic diarrhea virus / Q000302:isolation & purification*; D013552:Swine; D013553:Swine Diseases / Q000473:pathology* / Q000821:virology*; D014766:Viremia / Q000821:virology; D014774:Virulence / Q000235:genetics; D017201:Virus Shedding