title: Studies on the blood group affiliation of patients with liver hemangioma.
abstract: BACKGROUND
  Regardless of the improvement of the imaging methods for diagnosing the focal lesions of the liver, the etiological nature of the processes often remains unspecified. It is known that the blood cells and the vessels both originate from the mesenchyme, which is one of the embryos constituting a part of the mean embryonic layer--the mesoderm.
  
  
  OBJECTIVE
  We set out the goal of establishing, on the basis of our clinical material, whether there is a connection between the blood group affiliation, according to the ABO system, and the liver hemangioma.
  
  
  METHODS
  The ABO blood group affiliation of patients with liver hemangioma, operated at the Department of General and Liver-pancretatic Surgery, UH "Alexandrovska", in the period from 1995 to April 2013 was as follows: Group 0 - 14 patients (19.4%), Group A - 47 (65.3%), Group B - 6 (8.3%) and Group AB - 5 (6.9%). In the control group of patients: Group 0 - 28 (36.8%), Group A - 25 (32.9%), Group B - 15 (19.7%) and Group AB - 8 (10.5%). Data about the country: Group 0 - 32%, Group A - 44%, Group B - 15% and Group AB - 8%. The patients' blood group affiliation was determined based on the Moc method.
  
  
  RESULTS
  We established considerable statistical dependence between Blood Group A, i.e. aglutinogen and patients with liver hemangioma (p < 0.001.).
  
  
  CONCLUSIONS
  The possibility for genetic determination of the liver hemangioma is confirmed, which makes it possible to determine a group of people (with Blood Group A affiliation) with higher risk of developing hemangioma. The conclusion may serve for early diagnostics or as an additional factor for finding a solution to difficult cases in differential-diagnostic terms.
authors.forename: A
authors.initials: A
authors.lastname: Taseva
authors.forename: Vl
authors.initials: V
authors.lastname: Tasev
authors.forename: V
authors.initials: V
authors.lastname: Dimitrova
authors.forename: J
authors.initials: J
authors.lastname: Ilieva
mesh_terms: D000017:ABO Blood-Group System / Q000097:blood*; D002031:Bulgaria / Q000453:epidemiology; D006391:Hemangioma / Q000097:blood* / Q000453:epidemiology / Q000473:pathology; D006801:Humans; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000097:blood* / Q000453:epidemiology / Q000473:pathology; D012307:Risk Factors
chemical_list: D000017:ABO Blood-Group System