title: Metal-free oxidative synthesis of quinazolinones via dual amination of sp3 C-H bonds.
abstract: A novel metal-free synthesis of quinazolinones via dual amination of sp(3) C-H bonds was developed. The sp(3) carbon in methylarenes or adjacent to a heteroatom in DMSO, DMF or DMA was used as the one carbon synthon.
authors.affiliation: State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, P. R. China. lijxnju@nju.edu.cn.
authors.forename: Dan
authors.initials: D
authors.lastname: Zhao
authors.forename: Teng
authors.initials: T
authors.lastname: Wang
authors.forename: Jian-Xin
authors.initials: JX
authors.lastname: Li
mesh_terms: D000586:Amination; D001557:Benzenesulfonates / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D008670:Metals / Q000737:chemistry; D010084:Oxidation-Reduction; D011789:Quantum Theory; D052999:Quinazolinones / Q000138:chemical synthesis / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry
chemical_list: D001557:Benzenesulfonates; D008670:Metals; D052999:Quinazolinones; D012997:Solvents; D002244:Carbon; D006859:Hydrogen; C029501:4-toluenesulfonic acid