title: Influence of radiofrequency surgery on architecture of the palatine tonsils.
abstract: Radiofrequency surgery is a widely used modern technique for submucosal volume reduction of the tonsils. So far there is very limited information on morphologic changes in the human tonsils after radiofrequency surgery. We performed histopathological study of tonsillectomy specimens after previous bipolar radiofrequency induced thermotherapy (RFITT). A total of 83 patients underwent bipolar RFITT for hypertrophy of palatine tonsils. Tonsil volume reduction was measured by 3D ultrasonography. Five patients subsequently underwent tonsillectomy. Profound histopathological examination was performed to determine the effect of RFITT on tonsillar architecture. All tonsillectomy specimens showed the intact epithelium, intact germinal centers, normal vascularization, and no evidence of increased fibrosis. No microscopic morphological changes in tonsillectomy specimens after bipolar RFITT were observed. RFITT is an effective submucosal volume reduction procedure for treatment of hypertrophic palatine tonsils with no destructive effect on microscopic tonsillar architecture and hence most probably no functional adverse effect.
authors.affiliation: Department of Otorhinolaryngology and Head and Neck Surgery, First Faculty of Medicine, Charles University and Faculty Hospital Motol, V Uvalu 84, 150 06 Prague 5, Czech Republic.
authors.forename: Jan
authors.initials: J
authors.lastname: Plzak
authors.affiliation: Department of Pathology and Molecular Medicine, Second Faculty of Medicine, Charles University, V Uvalu 84, 150 06 Prague 5, Czech Republic.
authors.forename: Pavla
authors.initials: P
authors.lastname: Macokova
authors.affiliation: Department of Otorhinolaryngology and Head and Neck Surgery, First Faculty of Medicine, Charles University and Faculty Hospital Motol, V Uvalu 84, 150 06 Prague 5, Czech Republic.
authors.forename: Michal
authors.initials: M
authors.lastname: Zabrodsky
authors.affiliation: Department of Otorhinolaryngology and Head and Neck Surgery, First Faculty of Medicine, Charles University and Faculty Hospital Motol, V Uvalu 84, 150 06 Prague 5, Czech Republic.
authors.forename: Jan
authors.initials: J
authors.lastname: Kastner
authors.affiliation: Department of Otorhinolaryngology and Head and Neck Surgery, First Faculty of Medicine, Charles University and Faculty Hospital Motol, V Uvalu 84, 150 06 Prague 5, Czech Republic.
authors.forename: Petr
authors.initials: P
authors.lastname: Lastuvka
authors.affiliation: Department of Otorhinolaryngology and Head and Neck Surgery, First Faculty of Medicine, Charles University and Faculty Hospital Motol, V Uvalu 84, 150 06 Prague 5, Czech Republic.
authors.forename: Jaromir
authors.initials: J
authors.lastname: Astl
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D008297:Male; D009929:Organ Size; D014066:Palatine Tonsil / Q000473:pathology / Q000528:radiation effects* / Q000601:surgery*; D000078702:Radiofrequency Therapy; D014068:Tonsillectomy / Q000379:methods*; D055815:Young Adult