title: The diagnostic usefulness of video capsule endoscopy in adolescent immunoglobulin A vasculitis (Henoch-Schonlein purpura).
abstract: Immunoglobulin (Ig) A vasculitis (IgAV), previously known as Henoch-Schönlein purpura, is a systemic IgA-mediated leukocytoclastic vasculitis that usually affects children. We report the usefulness of video capsule endoscopy in 2 adolescent patients with IgAV having gastrointestinal involvement. Both patient 1, a 15-year-old girl, and patient 2, a 14-year-old boy, presented with purpuric rash and abdominal pain. Video capsule endoscopy showed multiple areas of purpuric erythema throughout the small bowel in both patients and showed multiple ulcers with bleeding in patient 2. Patient 1 responded well to oral prednisolone at a dose of 0.5 mg/kg/day. However, in patient 2, prednisolone at a dose of 0.5 mg/kg/day failed to control the symptoms; therefore, the dose was increased to 1 mg/kg/day to provide relief. Video capsule endoscopy was safe in both cases and produced no side effects. In conclusion, video capsule endoscopy is a useful tool for evaluating small bowel lesions in patients with IgAV and provides valuable information for the treatment of IgAV with gastrointestinal involvement.
authors.affiliation: Department of Dermatology, Nippon Medical School.
authors.forename: Min
authors.initials: M
authors.lastname: Li
authors.forename: Tokuya
authors.initials: T
authors.lastname: Omi
authors.forename: Yoko
authors.initials: Y
authors.lastname: Matano
authors.forename: Shunji
authors.initials: S
authors.lastname: Fujimori
authors.forename: Seiji
authors.initials: S
authors.lastname: Kawana
mesh_terms: D000293:Adolescent; D053704:Capsule Endoscopy; D005260:Female; D006801:Humans; D011695:IgA Vasculitis / Q000175:diagnosis*; D007421:Intestine, Small / Q000473:pathology; D008297:Male