title: Sporadic hemangioblastoma of the retroperitoneum.
abstract: Hemangioblastoma is a rare neoplasm occurred in soft tissue. Herein, we present an intriguing case of sporadic hemangioblastoma in the retroperitoneum occurring in a 59-year-old male. The tumor was characterized by an alternation of cellular and paucicellular areas surrounded by a thick fibrous capsule. The stromal cells showed a pale cytoplasm exhibiting occasional lipid droplets and hyperchromatic, irregularly nuclei. CD56, NSE, a-inhibin and S100 were positive in tumor cells. This is the third reported case of a hemangioblastoma in the retroperitoneum. Based on clinical examination, computed tomography imaging, surgical operation, and histopathologic studies, a definitive diagnosis was made. Further characteristic images and pathology of this disease are discussed.
authors.affiliation: Department of Pathology, 251 Hospital of PLA Zhangjiakou, 075000, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Huang
authors.affiliation: Department of Pathology, The First Affiliated Hospital of Hebei North University Zhangjiakou, 075000, China.
authors.forename: Xiang-Chun
authors.initials: XC
authors.lastname: Han
authors.affiliation: Department of Diagnostic Imaging, 251 Hospital of PLA Zhang Jiakou, 075000, China.
authors.forename: Guo-Shi
authors.initials: GS
authors.lastname: Lv
mesh_terms: D019002:CD56 Antigen / Q000378:metabolism; D018325:Hemangioblastoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007265:Inhibins / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D009418:S100 Proteins / Q000378:metabolism; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D019002:CD56 Antigen; D009418:S100 Proteins; C094377:inhibin-alpha subunit; D007265:Inhibins
keywords: Hemangioblastoma; immunohistochemistry; retroperitoneum; soft tissue