Light-emitting hair follicles: studying skin regeneration with in vivo imaging.
Cutting-edge imaging technologies and new luminescent and fluorescent genetic tools now make it possible to study hair regeneration in vivo in real time at the microscopic single-cell level and at the macroscopic level of hair follicle populations. These technologies also allow for noninvasive assessment of the skin's clinically relevant homeostatic parameters, such as oxidative stress levels and pH.
Department of Developmental and Cell Biology, Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, California, USA.
Christian Fernando
CF
Guerrero-Juarez
Department of Developmental and Cell Biology, Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, California, USA.
Raul
R
Ramos
Department of Developmental and Cell Biology, Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, California, USA.
Ji Won
JW
Oh
Department of Developmental and Cell Biology, Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, California, USA.
Tsai-Ching
TC
Hsi
Department of Developmental and Cell Biology, Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, California, USA. Electronic address: plikus@uci.edu.
Maksim V
MV
Plikus
D000818:Animals; D005260:Female; D006197:Hair / Q000196:embryology*; D018859:Hair Follicle / Q000254:growth & development*; D006801:Humans; D018384:Oxidative Stress; D011247:Pregnancy; D012867:Skin / Q000378:metabolism* / Q000503:physiopathology*; D060449:Wnt Signaling Pathway; D051176:beta Catenin / Q000378:metabolism*
C495267:CTNNB1 protein, mouse; D051176:beta Catenin