[Human herpesvirus 6 encephalitis in a patient with glucocorticoid therapy for inflammatory abdominal aortic aneurysm].
A 73-year-old man with inflammatory abdominal aortic aneurysm was admitted with headache and fever. Chest computed tomography (CT) revealed pneumonia and antibiotic therapy was started. Short-term memory impairment was observed and his consciousness had been rapidly deteriorated with seazure. Fluid-attenuated inversion recovery (FLAIR) image and diffusion-weighted magnetic resonance image (DWI) showed high intensity signals around bilateral limbic areas and herpes simplex encephalitis was suspected. After human herpesvirus (HHV)-6 DNA was amplified from cerebrospinal fluid, he was diagnosed with HHV-6 encephalitis and treated with gancyclovir. Clinicians need to be aware that glucocorticoid treatment for elderly can cause HHV-6 encephalitis.
Department of Gastroenterology, Rheumatology and Clinical Immunology, Sapporo Medical University School of Medicine.
Hidetaka
H
Yajima
Motohisa
M
Yamamoto
Tetsuya
T
Tabeya
Chisako
C
Suzuki
Tetsuyuki
T
Igarashi
Mikiko
M
Matsui
Yasuyoshi
Y
Naishiro
Hiroki
H
Takahashi
Yasuhisa
Y
Shinomura
D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000188:drug therapy*; D018792:Encephalitis, Viral / Q000209:etiology*; D005938:Glucocorticoids / Q000009:adverse effects*; D015654:Herpesvirus 6, Human; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000009:adverse effects*; D019349:Roseolovirus Infections / Q000209:etiology*
D005938:Glucocorticoids; D011239:Prednisolone