Second-line therapy in non-small-cell lung cancer: the DELTA between different genotypes widens.
Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada.
Alona
A
Zer
Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada Natasha.Leighl@uhn.ca.
Natasha B
NB
Leighl
D000230:Adenocarcinoma / Q000175:diagnosis / Q000188:drug therapy; D000077192:Adenocarcinoma of Lung; D000077548:Anaplastic Lymphoma Kinase; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000032:analysis* / Q000235:genetics; D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy* / Q000235:genetics; D002945:Cisplatin / Q000008:administration & dosage / Q000009:adverse effects; D004268:DNA-Binding Proteins / Q000032:analysis; D000077143:Docetaxel; D066246:ErbB Receptors / Q000235:genetics; D000069347:Erlotinib Hydrochloride; D005260:Female; D020869:Gene Expression Profiling; D005838:Genotype; D005971:Glutamates / Q000008:administration & dosage / Q000009:adverse effects; D006147:Guanine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives; D006801:Humans; D053552:Keratin-7 / Q000032:analysis; D008175:Lung Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy* / Q000235:genetics; D008875:Middle Aged; D010166:Palliative Care / Q000379:methods*; D000068437:Pemetrexed; D016066:Pleural Effusion, Malignant / Q000209:etiology; D011799:Quinazolines / Q000008:administration & dosage / Q000009:adverse effects; D018714:Radiotherapy, Adjuvant; D016032:Randomized Controlled Trials as Topic; D020794:Receptor Protein-Tyrosine Kinases / Q000235:genetics; D043823:Taxoids / Q000008:administration & dosage / Q000009:adverse effects; D014157:Transcription Factors; D017211:Treatment Failure
D014408:Biomarkers, Tumor; D004268:DNA-Binding Proteins; D005971:Glutamates; D053552:Keratin-7; D011799:Quinazolines; C504003:TTF1 protein, human; D043823:Taxoids; D014157:Transcription Factors; D000068437:Pemetrexed; D000077143:Docetaxel; D006147:Guanine; D000069347:Erlotinib Hydrochloride; D000077548:Anaplastic Lymphoma Kinase; C512478:EGFR protein, human; D066246:ErbB Receptors; D020794:Receptor Protein-Tyrosine Kinases; D002945:Cisplatin