Genomics of wood-degrading fungi.
Woody plants convert the energy of the sun into lignocellulosic biomass, which is an abundant substrate for bioenergy production. Fungi, especially wood decayers from the class Agaricomycetes, have evolved ways to degrade lignocellulose into its monomeric constituents, and understanding this process may facilitate the development of biofuels. Over the past decade genomics has become a powerful tool to study the Agaricomycetes. In 2004 the first sequenced genome of the white rot fungus Phanerochaete chrysosporium revealed a rich catalog of lignocellulolytic enzymes. In the decade that followed the number of genomes of Agaricomycetes grew to more than 75 and revealed a diversity of wood-decaying strategies. New technologies for high-throughput functional genomics are now needed to further study these organisms.
US Department of Energy Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, United States. Electronic address: raohm@lbl.gov.
Robin A
RA
Ohm
US Department of Energy Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, United States.
Robert
R
Riley
US Department of Energy Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, United States.
Asaf
A
Salamov
US Department of Energy Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, United States; Computational & Synthetic Biology Laboratory, College of Life Sciences & Biotechnology, Korea University, Anam-dong, Seongbuk-gu, Seoul 136-713, South Korea.
Byoungnam
B
Min
US Department of Energy Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, United States; Computational & Synthetic Biology Laboratory, College of Life Sciences & Biotechnology, Korea University, Anam-dong, Seongbuk-gu, Seoul 136-713, South Korea.
In-Geol
IG
Choi
US Department of Energy Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, United States. Electronic address: ivgrigoriev@lbl.gov.
Igor V
IV
Grigoriev
D001487:Basidiomycota / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism*; D044602:Cellulases / Q000378:metabolism; D016681:Genome, Fungal; D023281:Genomics / Q000379:methods / Q000639:trends; D053858:Metabolic Networks and Pathways / Q000235:genetics; D014934:Wood / Q000378:metabolism* / Q000382:microbiology*
D044602:Cellulases
Agaricomycetes; Comparative genomics; Fungal genomics; Lignocellulose degradation; Sequencing; Wood decay