Acute case-fatality rates of stroke and acute myocardial infarction in a Japanese population: Takashima stroke and AMI registry, 1989-2005.
BACKGROUND
Few comprehensive stroke and acute myocardial infarction registries of long duration exist in Japan to illustrate trends in acute case-fatality of stroke and acute myocardial infarction with greater precision. We examined 17-year case-fatality rates of stroke and acute myocardial infarction using an entire community-monitoring registration system to investigate trends in these rates over time in a Japanese population.


METHODS
Data were obtained from the Takashima Stroke and AMI Registry covering a stable population of approximately 55 000 residents of Takashima County in central Japan. We divided the total observation period of 17 years into four periods, 1989-1992, 1993-1996, 1997-2000, and 2001-2005. We calculated gender, age-specific and age-adjusted acute case-fatality rates (%) of stroke and acute myocardial infarction across these four periods.


RESULTS
During the study period of 1989-2005, there were 341 fatal cases within 28 days of onset among 2239 first-ever stroke events and 163 fatal cases among 433 first-ever acute myocardial infarction events. The age-adjusted acute case-fatality rate of stroke was 14·9% in men and 15·7% in women. The age-adjusted acute case-fatality rate of acute myocardial infarction was 34·3% in men and 43·3% in women. The age-adjusted acute case-fatality rates of stroke and acute myocardial infarction showed insignificant differences across the four time periods. The average annual change in the acute case-fatality rate of stroke (-0·2%; 95% CI: -2·4-2·1) and acute myocardial infarction (2·7%; 95% CI: -0·7-6·1) did not change significantly across the study years.


CONCLUSIONS
The acute case-fatality rates of stroke and acute myocardial infarction have remained stable from 1989 to 2005 in a rural and semi-urban Japanese population.
Department of Health Science, Shiga University of Medical Science, Shiga, Japan; Sleep Center, Foothills Medical Center, Calgary, Alberta, Canada.
Nahid
N
Rumana
Yoshikuni
Y
Kita
Tanvir Chowdhury
TC
Turin
Yasuyuki
Y
Nakamura
Naoyuki
N
Takashima
Masaharu
M
Ichikawa
Hideki
H
Sugihara
Yutaka
Y
Morita
Kunihiko
K
Hirose
Kenzou
K
Kawakami
Akira
A
Okayama
Katsuyuki
K
Miura
Hirotsugu
H
Ueshima
D000208:Acute Disease; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002391:Catchment Area, Health / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology* / Q000401:mortality*; D012042:Registries; D012189:Retrospective Studies; D020521:Stroke / Q000453:epidemiology* / Q000401:mortality*
Japan; acute myocardial infarction; case-fatality; epidemiology; stroke; trend