Paravertebral mushroom: identification of a novel species of Phellinus as a human pathogen in chronic granulomatous disease.
We describe a case of paravertebral abscess caused by a Phellinus sp. in a boy with chronic granulomatous disease. Sequence-based identification of this mold, a new agent of disease, suggests a close relation to Phellinus umbrinellus.
Laboratory of Host Defenses, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Suk See
SS
De Ravin
Clinical Monitoring Research Program, Leidos Biomedical Research, Inc., Frederick, Maryland, USA.
Mark
M
Parta
Fungus Testing Laboratory, Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Deanna A
DA
Sutton
Department of Microbiology and Immunology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Brian L
BL
Wickes
Fungus Testing Laboratory, Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Elizabeth H
EH
Thompson
Fungus Testing Laboratory, Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Nathan P
NP
Wiederhold
Center for Forest Mycology Research, Northern Research Station, Forest Products Laboratory, USDA Forest Service, Madison, Wisconsin, USA.
Karen K
KK
Nakasone
Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Meghna
M
Alimchandani
Division of Immunology, Boston Children's Hospital, Boston, Massachusetts, USA.
Amy
A
OConnell
Division of Immunology, Boston Children's Hospital, Boston, Massachusetts, USA.
Luigi
L
Notarangelo
Laboratory of Host Defenses, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Elizabeth
E
Kang
Laboratory of Host Defenses, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Harry L
HL
Malech
Department of Laboratory Medicine Clinical Center, National Institutes of Health, Bethesda, Maryland, USA azelazny@mail.nih.gov.
Adrian M
AM
Zelazny
D000038:Abscess / Q000175:diagnosis* / Q000382:microbiology* / Q000473:pathology; D000935:Antifungal Agents / Q000494:pharmacology; D001487:Basidiomycota / Q000145:classification / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D002648:Child; D016000:Cluster Analysis; D004271:DNA, Fungal / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D021903:DNA, Ribosomal Spacer / Q000737:chemistry / Q000235:genetics; D020459:Genes, rRNA; D006105:Granulomatous Disease, Chronic / Q000150:complications*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D009181:Mycoses / Q000175:diagnosis* / Q000382:microbiology* / Q000473:pathology; D010802:Phylogeny; D012331:RNA, Fungal / Q000235:genetics; D012335:RNA, Ribosomal / Q000235:genetics; D011860:Radiography, Abdominal; D013902:Radiography, Thoracic; D017422:Sequence Analysis, DNA; D014057:Tomography, X-Ray Computed
D000935:Antifungal Agents; D004271:DNA, Fungal; D004275:DNA, Ribosomal; D021903:DNA, Ribosomal Spacer; D012331:RNA, Fungal; D012335:RNA, Ribosomal; C065096:RNA, ribosomal, 26S