Improvement in severe psoriasis associated with isoniazid treatment.
A 67 year-old man was diagnosed 10 years ago with severe plaque psoriasis and was hospitalized for re-evaluation of therapy. He was treated previously with topical corticosteroids, methotrexate, and phototherapy. As part of the assessment protocol for initiation of biological treatment, a tuberculin skin test was done, which was positive without signs of active tuberculosis. Isoniazid therapy was started with marked improvement of psoriatic lesions before biologic treatment could be initiated.
Anca
A
Chiriac
Dan
D
Ferariu
Caius
C
Solovan
6th Military Support Unit, Poland.
Piotr
P
Brzezinski
Steven R
SR
Feldman
D000368:Aged; D000995:Antitubercular Agents / Q000627:therapeutic use*; D005148:Facial Dermatoses / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use*; D008297:Male; D011565:Psoriasis / Q000150:complications / Q000188:drug therapy*; D014376:Tuberculosis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*
D000995:Antitubercular Agents; D007538:Isoniazid