Adverse reaction to sublingual Parietaria vaccine following an ultra-rush induction.
In the treatment of respiratory allergies Sublingual Immunotherapy (SLIT) represents a valid alternative to Subcutaneous Immunotherapy (SCIT) for its better safety profile. We describe a case of acute severe asthma following the first maintenance dose of SLIT in a boy allergic to Parietaria pollen. At the initiation of therapy, the patient was in healthy condition and his asthma appeared to be under control. An ultra-rush induction had given no reaction. Despite the good safety profile of SLIT, clinicians should be aware of the risk of adverse effects when prescribing SLIT for respiratory allergies.
U.O.S.D. Allergologia e Immunologia Clinica, Loreto Crispi Hospital, Naples, Italy. E-mail: guglielmoscala@gmail.com.
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Scala
U.O.S.D. Allergologia e Immunologia Clinica, Loreto Crispi Hospital, Naples, Italy.
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Ciccarelli
U.O.S.D. Allergologia e Immunologia Clinica, Loreto Crispi Hospital, Naples, Italy.
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Calabrò
D000208:Acute Disease; D000286:Administration, Sublingual; D052179:Antigens, Plant / Q000008:administration & dosage / Q000009:adverse effects*; D001249:Asthma / Q000139:chemically induced* / Q000175:diagnosis / Q000276:immunology; D002648:Child; D004334:Drug Administration Schedule; D006801:Humans; D008297:Male; D032403:Parietaria / Q000276:immunology*; D006255:Rhinitis, Allergic, Seasonal / Q000175:diagnosis / Q000276:immunology / Q000628:therapy*; D012307:Risk Factors; D012720:Severity of Illness Index; D063729:Sublingual Immunotherapy / Q000009:adverse effects*; D014612:Vaccines / Q000008:administration & dosage / Q000009:adverse effects*
D052179:Antigens, Plant; D014612:Vaccines
Parietaria; Pellitory; SLIT; adverse effects; asthma