A Rh-catalyzed regio- and stereoselective route to enamides: benzamides as assembling reagents.
A new protocol for the synthesis of fully substituted enaminones has been achieved using a diverse range of benzamides and 1-sulfonyl-1,2,3-triazoles. Selective removal of the β-amino moiety of the obtained α-amido-enaminones to form Z-enamides was also demonstrated thus improving the synthetic value of benzamides for structural diversities in a minimum number of synthetic steps.
Department of Chemistry, Kangwon National University, 1 Kangwondaehak-gil, Chuncheo-si, Gangwon-do, 200-791, Republic of Korea. ejyoo@kangwon.ac.kr.
Dong Jin
DJ
Lee
Jinhwan
J
Shin
Eun Jeong
EJ
Yoo