Conformational regulation of integrin activation in drug discovery.
Takayuki
T
Okamoto
Motomu
M
Shimaoka
D001327:Autoimmune Diseases / Q000188:drug therapy / Q000235:genetics; D002448:Cell Adhesion / Q000235:genetics; D015815:Cell Adhesion Molecules; D002465:Cell Movement / Q000235:genetics; D002634:Chemotaxis, Leukocyte / Q000235:genetics; D055808:Drug Discovery; D005109:Extracellular Matrix / Q000378:metabolism; D006801:Humans; D007249:Inflammation / Q000188:drug therapy / Q000235:genetics / Q000276:immunology*; D016023:Integrins / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D007962:Leukocytes / Q000276:immunology*; D008024:Ligands; D008565:Membrane Proteins / Q000378:metabolism; D008968:Molecular Conformation; D058990:Molecular Targeted Therapy; D009154:Mutation; D009369:Neoplasms / Q000188:drug therapy / Q000235:genetics; D017434:Protein Structure, Tertiary; D015398:Signal Transduction / Q000502:physiology; D013927:Thrombosis / Q000188:drug therapy / Q000235:genetics
D015815:Cell Adhesion Molecules; D016023:Integrins; D008024:Ligands; D008565:Membrane Proteins