Scurvy revealed by difficulty walking: three cases in young children.
Scurvy is rare in developed countries but is known to cause lower-extremity pain and refusal to ambulate in children. Since the discovery of the link between scurvy and dietary deficiency of ascorbic acid, there has been a substantial decrease in its prevalence and recognition. Here we describe 3 cases of scurvy in young children presenting with difficulty walking. Only 1 of 3 patients had gingival lesions at the initial presentation. Two cases underwent an extensive evaluation for hematologic and rheumatologic diseases before the diagnosis of scurvy was made. Dietary histories eventually revealed that all 3 patients had sharply limited intake of fruits and vegetables secondary to oral aversion, and 1 patient had autism. Radiographic changes of long bones were observed in all patients. Interestingly, all patients had concomitant vitamin D deficiency. After replacement with vitamin C, all patients recovered and started to walk again with improved leg pain. These clinical manifestations and radiologic findings highlight the importance for rheumatologists to have a higher index of suspicion for scurvy in nonambulatory children.
From the Departments of *Pediatrics and †Radiology, Washington University School of Medicine, St Louis, MO.
Maleewan
M
Kitcharoensakkul
Christa G
CG
Schulz
Rachel
R
Kassel
Geetika
G
Khanna
Shannon
S
Liang
Alexander
A
Ngwube
Kevin W
KW
Baszis
David A
DA
Hunstad
Andrew J
AJ
White
D001205:Ascorbic Acid / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D051346:Mobility Limitation; D012614:Scurvy / Q000175:diagnosis* / Q000188:drug therapy; D016138:Walking
D001205:Ascorbic Acid