Laboratory monitoring of bacterial gastroenteric pathogens Salmonella and Shigella in Shanghai, China 2006-2012.
In 2006 we initiated an enhanced laboratory-based surveillance of Salmonella and Shigella infections in Shanghai, China. A total of 4483 Salmonella and 2226 Shigella isolates were recovered from stool specimens by 2012. In 80 identified Salmonella serovars, Enteritidis (34·5%) and Typhimurium (26·2%) were the most common. Shigella (S.) sonnei accounted for 63·9% of human Shigella infections over the same time period, and replaced S. flexneri to become the primary cause of shigellosis since 2010. Overall, a high level of antimicrobial resistance was observed in Salmonella and Shigella, particularly to nalidixic acid, ampicillin, and tetracycline. Ciprofloxacin resistance was common in Salmonella Typhimurium (21·0%) and S. flexneri (37·6%). The cephalosporin resistance in both pathogens also increased over the years, ranging from 3·4% to 7·0% in Salmonella, and from 10·4% to 28·6% in Shigella. Resistance to multiple antimicrobials was also identified in a large number of the isolates. This study provides insight into the distribution of Salmonella and Shigella in diarrhoeal diseases.
Department of Food Science and Technology, School of Agriculture and Biology,Shanghai Jiao Tong University,Shanghai,P.R. China.
J
J
Zhang
Department of Nutrition and Food Science,University of Maryland,College Park, MD,USA.
F
F
Wang
Shanghai Municipal Center for Disease Control and Prevention,Shanghai,P.R. China.
H
H
Jin
Shanghai Municipal Center for Disease Control and Prevention,Shanghai,P.R. China.
J
J
Hu
Shanghai Municipal Center for Disease Control and Prevention,Shanghai,P.R. China.
Z
Z
Yuan
Shanghai Municipal Ke-Ma-Jia Technology Center for Microbiology,Shanghai,P.R. China.
W
W
Shi
Department of Food Science and Technology, School of Agriculture and Biology,Shanghai Jiao Tong University,Shanghai,P.R. China.
X
X
Yang
Department of Food Science and Technology, School of Agriculture and Biology,Shanghai Jiao Tong University,Shanghai,P.R. China.
J
J
Meng
Shanghai Municipal Center for Disease Control and Prevention,Shanghai,P.R. China.
X
X
Xu
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D024881:Drug Resistance, Bacterial; D004405:Dysentery, Bacillary / Q000453:epidemiology* / Q000382:microbiology; D005243:Feces / Q000382:microbiology; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D015995:Prevalence; D012475:Salmonella / Q000145:classification / Q000302:isolation & purification*; D012480:Salmonella Infections / Q000453:epidemiology* / Q000382:microbiology; D012760:Shigella / Q000145:classification / Q000302:isolation & purification*; D055815:Young Adult
D000900:Anti-Bacterial Agents
Antimicrobial susceptibility; Salmonella; Shigella; gastroenteritis