Central venous catheter infection-induced Henoch-Schönlein purpura in a patient on hemodialysis.
A 69-year-old man, who had been dialyzed using a permanent central venous catheter for 2 years, presented with Henoch-Schönlein purpura and positive perinuclear anti-neutrophil cytoplasmic antibody (p-ANCA). He was diagnosed with catheter-related infection by Staphylococcus aureus. After administration of antibiotic and steroid therapy, purpura disappeared and p-ANCA gradually became negative. This case supports the conclusion that infection can be pathogenesis of the vasculitis, including ANCA-positive HSP. Additionally, impregnation of catheters with antibiotics can be an effective treatment for catheter infections.
Department of Nephrology, the 306th Hospital of Chinese PLA , Beijing , China.
Jian Jun
JJ
Gao
Jia Mei
JM
Wei
Yue Hua
YH
Gao
Shuang
S
Li
Yu
Y
Na
D000368:Aged; D056648:Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / Q000209:etiology*; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood; D055499:Catheter-Related Infections / Q000276:immunology*; D062905:Central Venous Catheters / Q000009:adverse effects*; D006801:Humans; D011695:IgA Vasculitis / Q000276:immunology*; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy; D008297:Male; D006435:Renal Dialysis
D019268:Antibodies, Antineutrophil Cytoplasmic
Anti-neutrophil cytoplasmic antibody; Henoch-Schönlein purpura; central venous catheter infection; diabetic nephropathy; hemodialysis