Mother-child interaction is associated with neurocognitive outcome in extremely low gestational age children.
Early mother-child interaction is one of the factors suggested to have an impact on neurocognitive development of extremely low gestational age (ELGA) children. Our aim was to examine associations of mother-child interaction with neurocognitive outcome, neurological impairments and neonatal brain injuries in ELGA children. A prospective study of 48 ELGA children, born before 28 gestational weeks (26.3 ± 1.2 weeks, birth weight 876 g ± 194 g), and 16 term controls. Brain MRI was performed at term-equivalent age. At two years of corrected age, the mother-child interaction was assessed in a structured play situation using the Erickson Scales and Mutually Responsive Orientation Scales. Neurocognitive outcome was assessed with Griffiths Mental Developmental Scales (GMDS) and Bayley Scales of Infant and Toddler Development - Third Edition (BSID-III) and with Hempel neurological examination. Among ELGA children, higher quality of dyadic relationship and maternal sensitivity, responsiveness, and supportiveness were associated with positive neurocognitive outcome measured both with GMDS and BSID-III (adjusted p < 0.05). This association remained after adjusting for mother's educational level. Neurological impairments at two years, white matter or gray matter abnormalities in MRI at term-equivalent age, and grade III-IV intraventricular hemorrhage during the neonatal period were not associated with mother-child interaction. This study emphasizes the importance of the quality of mother-child interaction after extremely preterm birth for neurocognitive development. Neonatal brain injury and neurological impairments were not associated with worse parent-child interaction after two years.
Children's Hospital, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland.
Petri
P
Rahkonen
Kati
K
Heinonen
Anu-Katriina
AK
Pesonen
Aulikki
A
Lano
Taina
T
Autti
Riina
R
Puosi
Ea
E
Huhtala
Sture
S
Andersson
Marjo
M
Metsäranta
Katri
K
Räikkönen
D001921:Brain / Q000473:pathology*; D002657:Child Development / Q000502:physiology*; D002675:Child, Preschool; D003071:Cognition / Q000502:physiology*; D005260:Female; D006801:Humans; D062071:Infant, Extremely Premature / Q000523:psychology*; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D008425:Maternal Behavior; D009034:Mother-Child Relations; D010988:Play and Playthings
Mother-child interaction; neonate; neurocognition; neurodevelopment; preterm