Passive smoking and preterm birth in urban China.
Studies investigating the relationship between maternal passive smoking and the risk of preterm birth have reached inconsistent conclusions. A birth cohort study that included 10,095 nonsmoking women who delivered a singleton live birth was carried out in Lanzhou, China, between 2010 and 2012. Exposure to passive smoking during pregnancy was associated with an increased risk of very preterm birth (<32 completed weeks of gestation; odds ratio = 1.98, 95% confidence interval: 1.41, 2.76) but not moderate preterm birth (32-36 completed weeks of gestation; odds ratio = 0.98, 95% confidence interval: 0.81, 1.19). Risk of very preterm birth increased with the duration of exposure (P for trend = 0.0014). There was no variability in exposures by trimester. The associations were consistent for both medically indicated and spontaneous preterm births. Overall, our findings support a positive association between passive smoking and the risk of very preterm birth.
Jie
J
Qiu
Xiaochun
X
He
Hongmei
H
Cui
Chong
C
Zhang
Honghong
H
Zhang
Yun
Y
Dang
Xudong
X
Han
Ya
Y
Chen
Zhongfeng
Z
Tang
Hanru
H
Zhang
Haiya
H
Bai
Ruifeng
R
Xu
Daling
D
Zhu
Xiaojuan
X
Lin
Ling
L
Lv
Xiaoying
X
Xu
Ru
R
Lin
Tingting
T
Yao
Jie
J
Su
Xiaohui
X
Liu
Wendi
W
Wang
Yueyuan
Y
Wang
Bin
B
Ma
Sufen
S
Liu
Huang
H
Huang
Catherine
C
Lerro
Nan
N
Zhao
Jiaxin
J
Liang
Shuangge
S
Ma
Richard A
RA
Ehrenkranz
Qing
Q
Liu
Yawei
Y
Zhang
D000293:Adolescent; D000328:Adult; D002681:China / Q000453:epidemiology; D004522:Educational Status; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008423:Maternal Age; D010298:Parity; D011247:Pregnancy; D047928:Premature Birth / Q000453:epidemiology / Q000209:etiology*; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014028:Tobacco Smoke Pollution / Q000009:adverse effects* / Q000706:statistics & numerical data; D014505:Urban Population / Q000706:statistics & numerical data; D055815:Young Adult
D014028:Tobacco Smoke Pollution
China; birth cohort; passive smoking; preterm birth