What happens to patients with COPD with long-term oxygen treatment who receive mechanical ventilation for COPD exacerbation? A 1-year retrospective follow-up study.
We performed a retrospective cohort study of patients with chronic obstructive lung disease (COPD) on long-term oxygen treatment (LTOT) who received invasive mechanical ventilation for COPD exacerbation. Of the 4791 patients, 23% died in the hospital, and 45% died in the subsequent 12 months. 67% of patients were readmitted at least once in the subsequent 12 months, and 26.8% were discharged to a nursing home or skilled nursing facility within 30 days. We conclude that these patients have high mortality rates, both in-hospital and in the 12 months postdischarge. If patients survive, many will be readmitted to the hospital and discharged to nursing home. These potential outcomes may support informed critical care decision making and more preference congruent care.
Hofstra North Shore LIJ School of Medicine and North Shore LIJ Health System, Department of Medicine, Manhasset, New York, USA.
Negin
N
Hajizadeh
Department of Population Health, New York University School of Medicine, New York, New York, USA.
Keith
K
Goldfeld
Division of Pulmonary and Critical Care, University of Washington School of Medicine, Seattle, Washington, USA.
Kristina
K
Crothers
D000368:Aged; D000369:Aged, 80 and over; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000401:mortality* / Q000628:therapy*; D008297:Male; D006278:Medicare / Q000706:statistics & numerical data; D009735:Nursing Homes / Q000706:statistics & numerical data*; D010102:Oxygen Inhalation Therapy; D010359:Patient Readmission / Q000706:statistics & numerical data*; D012121:Respiration, Artificial; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D013997:Time Factors; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology
COPD Exacerbations; Long Term Oxygen Therapy (LTOT)