Two new avermectin derivatives from the Beibu Gulf gorgonian Anthogorgia caerulea.
Two new avermectin derivatives, avermectins B1c and B1e (1 and 2, resp.), as well as two known compounds, avermectin B2a (3) and ivermectin A1a (4), were isolated from a Beibu Gulf gorgonian coral, Anthogorgia caerulea. The structures of the new compounds were established by detailed spectroscopic analysis and by comparison with spectral data of related known compounds. Compounds 1-4 showed moderate antifouling activities against the larval settlement of Balanus amphitrite.
Guangxi Key Laboratory of Marine Environmental Science, Guangxi Academy of Sciences, Nanning 53007, P. R. China.
Chenghai
C
Gao
Yibing
Y
Wang
Yinning
Y
Chen
Bijuan
B
He
Rongcan
R
Zhang
Mingben
M
Xu
Riming
R
Huang
D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D057219:Biofouling / Q000517:prevention & control*; D004202:Disinfectants / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism; D007559:Ivermectin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D007814:Larva / Q000187:drug effects / Q000254:growth & development; D001468:Thoracica / Q000187:drug effects* / Q000254:growth & development
D004202:Disinfectants; C048324:abamectin; D007559:Ivermectin
Anthogorgia caerulea; Antifouling activity; Avermectins B1c and B1e