[Menopause and metabolic syndrome].
The incidence of cardiovascular disease increases considerably after the menopause. One reason for the increased cardiovascular risk seems to be determined by metabolic syndrome, in which all components (visceral obesity, dyslipidemia, hypertension, and glucose metabolism disorder) are associated with higher incidence of coronary artery disease. After menopause, metabolic syndrome is more prevalent than in premenopausal women, and may plays an important role in the occurrence of myocardial infarction and other atherosclerotic and cardiovascular morbidities. Obesity, an essential component of the metabolic syndrome, is also associated with increased incidence of breast, endometrial, bowel, esophagus, and kidney cancer. The treatment of metabolic syndrome is based on the change in lifestyle and, when necessary, the use of medication directed to its components. In the presence of symptoms of the climacteric syndrome, hormonal therapy, when indicated, will also contribute to the improvement of the metabolic syndrome.
Instituto Estadual de Diabetes e Endocrinologia Luiz Capriglione, Rio de Janeiro, RJ, Brasil.
Ricardo M R
RM
Meirelles
D003327:Coronary Disease / Q000150:complications / Q000188:drug therapy; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy; D050171:Dyslipidemias / Q000150:complications; D004958:Estradiol / Q000627:therapeutic use; D004967:Estrogens / Q000627:therapeutic use; D005260:Female; D018149:Glucose Intolerance; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D015994:Incidence; D007333:Insulin Resistance; D008019:Life Style; D008593:Menopause; D024821:Metabolic Syndrome / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control; D008875:Middle Aged; D009765:Obesity / Q000628:therapy; D016387:Women's Health
D004967:Estrogens; D004958:Estradiol