Chitosan-microreactor: a versatile approach for heterogeneous organic synthesis in microfluidics.
Microreactors have been proven to be efficient tools for a variety of homogeneous organic transformations due to their mixing efficiency, which results in very fast reactions, better heat and mass transfer, and simple scale-up. However, in heterogeneous catalytic reactions each catalyst needs an individual substrate as support. Herein, a versatile approach to immobilize metal catalysts on chitosan as a common substrate is presented. Chitosan, accommodating many metal catalysts, is grafted onto the microchannel surface as nanobrush. The versatility, catalytic efficiency, and stability/durability of the microreactor are demonstrated for a number of organic transformations involving various metal compounds as catalysts.
National Centre of Applied Microfluidic Chemistry, Dept. of Chem. Eng. POSTECH (Pohang Univ. of Sci.&Tech.), Pohang, 790-784 (South Korea), Fax: (+82)-54-279-2272 http://camc.postech.ac.kr/
K C
KC
Basavaraju
Siddharth
S
Sharma
Ajay K
AK
Singh
Do Jin
DJ
Im
Dong-Pyo
DP
Kim
D002384:Catalysis; D060326:Chemistry Techniques, Synthetic; D048271:Chitosan / Q000737:chemistry*; D046210:Microfluidic Analytical Techniques / Q000379:methods*; D009942:Organometallic Compounds / Q000737:chemistry; D013499:Surface Properties
D009942:Organometallic Compounds; D048271:Chitosan
chitosan; click reaction; heterogeneous catalysis; microreactor; nanostructures