Blood-brain barrier: a dual life of MFSD2A?
Two recent papers in Nature, Ben-Zvi et al. (2014) and Nguyen et al. (2014), report a surprising dual role for the blood-brain barrier transporter MFSD2A in both establishing BBB integrity and in uptake of the fatty acid DHA.
Zilkha Neurogenetic Institute and Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Zhen
Z
Zhao
Zilkha Neurogenetic Institute and Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA. Electronic address: zlokovic@usc.edu.
Berislav V
BV
Zlokovic
D000818:Animals; D001812:Blood-Brain Barrier / Q000196:embryology* / Q000502:physiology*; D001921:Brain / Q000378:metabolism*; D004281:Docosahexaenoic Acids / Q000378:metabolism*; D005260:Female; D008297:Male; D026901:Membrane Transport Proteins / Q000378:metabolism*
D026901:Membrane Transport Proteins; D004281:Docosahexaenoic Acids