Orthogonal tools to help determine the required selectivity of ligand-binding assays in drug development.
BioQualQuan, LLC, 370 Spring Park Road, Camarillo, CA 93012, USA. ljean095@gmail.com.
Jean W
JW
Lee
D001688:Biological Products / Q000032:analysis / Q000737:chemistry* / Q000494:pharmacology*; D015415:Biomarkers / Q000032:analysis; D002853:Chromatography, Liquid / Q000379:methods*; D015195:Drug Design; D055808:Drug Discovery; D008024:Ligands; D011506:Proteins / Q000032:analysis / Q000737:chemistry* / Q000494:pharmacology*; D053719:Tandem Mass Spectrometry / Q000379:methods*
D001688:Biological Products; D015415:Biomarkers; D008024:Ligands; D011506:Proteins
LC–MS/MS; PK–PD; ligand-binding assay; protein therapeutics; selectivity and specificity; soluble targets