Bioaccumulation of highly hydrophobic organohalogen flame retardants from sediments: application of toxicokinetics and passive sampling techniques.
Highly hydrophobic organohalogen flame retardants (HHOFRs) are found ubiquitously in the environment; therefore, a better understanding of their bioavailability is needed. In the current study, bioaccumulation testing using the oligochaete, Lumbriculus variegatus, and passive sampling (solid-phase microextraction (SPME)) were performed to study the bioaccumulation potential of HHOFRs, including decabromodiphenyl ether (deca-BDE), decabromodiphenyl ethane (DBDPE), and dechlorane plus (DP), in laboratory-spiked and field-collected sediments. The HHOFRs were bioavailable to L. variegatus even though their biota-sediment accumulation factors were low (0.016 ± 0.002 to 0.48 ± 0.082 g organic carbon/g lipid, syn-DP > anti-DP > deca-BDE > DBDPE). Hydrophobicity and stereoisomerism affected HHOFR bioavailability. Meanwhile, HHOFR concentrations on the SPME fibers (Cf) correlated with those in biota (Cb), suggesting the potential application of SPME in bioavailability prediction for those compounds. The log Cf to log Cb correlation for deca-BDE and DP had a greater intercept than that for polychlorinated biphenyls (data obtained from the literature) although the slopes were similar, while data for DBDPE fell on the regression line for PCBs, implying some uncertainty in application of SPMEs across chemical classes. The increasing sorptive ability of proteins for HHOFRs in comparison to the less-brominated BDEs suggested that protein-binding should be considered when estimating bioaccumulation potential of HHOFRs in benthic invertebrates.
State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences , Guangzhou, Guangdong 510640, China.
Huizhen
H
Li
Baozhong
B
Zhang
Yanli
Y
Wei
Fei
F
Wang
Michael J
MJ
Lydy
Jing
J
You
D000818:Animals; D001682:Biological Availability; D004129:Dimethylpolysiloxanes / Q000737:chemistry; D004784:Environmental Monitoring / Q000379:methods*; D005411:Flame Retardants / Q000378:metabolism* / Q000493:pharmacokinetics*; D019015:Geologic Sediments / Q000737:chemistry*; D006846:Hydrocarbons, Halogenated / Q000737:chemistry / Q000378:metabolism / Q000493:pharmacokinetics*; D057927:Hydrophobic and Hydrophilic Interactions; D000442:Octanols / Q000737:chemistry; D009835:Oligochaeta / Q000378:metabolism; D016062:Porosity; D011485:Protein Binding; D012710:Serum Albumin, Bovine / Q000378:metabolism; D052617:Solid Phase Microextraction / Q000379:methods*; D014867:Water / Q000737:chemistry
D004129:Dimethylpolysiloxanes; D005411:Flame Retardants; D006846:Hydrocarbons, Halogenated; D000442:Octanols; D014867:Water; D012710:Serum Albumin, Bovine