Application of electrochemical biosensors in clinical diagnosis.
Analyses in the clinical area need quick and reliable analytical methods and devices. For this purpose, biosensors can be a suitable option, whereas they are constructed to be simple for use, specific for the target analyte, capable of continuous monitoring and giving quick results, potentially low-costing and portable. In this article, we describe electrochemical biosensors developed for clinical diagnosis, namely for glucose, lactate, cholesterol, urea, creatinine, DNA, antigens, antibodies, and cancer markers assays. Chosen biosensors showed desirable sensitivity, selectivity, and potential for application on real samples. They are often designed to avoid interference with undesired components present in the monitored systems.
Institute of Biochemistry, Nutrition and Health Protection, Faculty of Chemical and Food Technology, Slovak University of Technology, Bratislava, Slovak Republic. rasto.monosik@gmail.com, rastislav.monosik@stuba.sk.
Rastislav
R
Monošík
Miroslav
M
Stred'anský
Ernest
E
Šturdík
D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods; D002784:Cholesterol / Q000032:analysis; D019411:Clinical Laboratory Techniques; D003401:Creatine / Q000032:analysis; D003404:Creatinine / Q000032:analysis; D055664:Electrochemical Techniques / Q000295:instrumentation / Q000379:methods; D005947:Glucose / Q000032:analysis; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis; D009696:Nucleic Acids / Q000032:analysis
D009696:Nucleic Acids; D002784:Cholesterol; D003404:Creatinine; D005947:Glucose; D003401:Creatine
amperometric; analysis; biosensor; clinical diagnosis; enzyme