Natural polyphenols and spinal cord injury.
Polyphenols have been shown to have some of the neuroprotective effects against neurodegenerative diseases. These effects are attributed to a variety of biological activities, including free radical scavenging/antioxidant and anti-inflammatory and anti-apoptotic activities. In this regard, many efforts have been made to study the effects of various well-known dietary polyphenols on spinal cord injury (SCI) and to explore the mechanisms behind the neuroprotective effects. The aim of this paper is to present the mechanisms of neuroprotection of natural polyphenols used in animal models of SCI.
Molecular and Cell Biology Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences, 18KM Khazar Blvd, Khazar Sq. Sari, Iran. m khalat90@yahoo.com.
Ali Reza
AR
Khalatbary
D000818:Animals; D001688:Biological Products / Q000627:therapeutic use*; D006801:Humans; D010944:Plants / Q000737:chemistry; D059808:Polyphenols / Q000627:therapeutic use*; D013119:Spinal Cord Injuries / Q000188:drug therapy*
D001688:Biological Products; D059808:Polyphenols
Spinal cord injury; Polyphenols; Herbal medicine