Prostate-specific antigen is unlikely to be a suitable biomarker of semen exposure from recent unprotected receptive anal intercourse in men who have sex with men.
A biomarker of unprotected receptive anal intercourse could improve validity of sexual behavior measurement. We quantified prostate-specific antigen (PSA) from rectal swabs from men who have sex with men (MSM). One swab was PSA positive. Using current methods, PSA is an inadequate biomarker of recent unprotected receptive anal intercourse in men who have sex with men.
From the *Division of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH; †Division of Infectious Diseases, School of Medicine, University of North Carolina, Chapel Hill, NC; ‡Division of Infectious Diseases and §Department of Obstetrics and Gynecology, College of Medicine, The Ohio State University, Columbus, OH; and ¶Sexual Health Clinic, Columbus Public Health, Columbus, OH.
Cara E
CE
Rice
Maria F
MF
Gallo
Marcia M
MM
Hobbs
Courtney D
CD
Lynch
Alison H
AH
Norris
John A
JA
Davis
Karen S
KS
Fields
Melissa
M
Ervin
Abigail Norris
AN
Turner
D000293:Adolescent; D000328:Adult; D001003:Anal Canal / Q000821:virology*; D015415:Biomarkers / Q000032:analysis*; D006679:HIV Seropositivity / Q000635:transmission*; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000032:analysis*; D012661:Semen / Q000737:chemistry*; D012725:Sexual Behavior; D012747:Sexual Partners; D011795:Surveys and Questionnaires; D013997:Time Factors
D015415:Biomarkers; D017430:Prostate-Specific Antigen