A fluorescent probe with restricted intramolecular rotation-induced emission for label-free detection of mercury ions.
Formation of T-Hg(2+)-T complexes changes the configuration of a single-stranded DNA, leading to enhanced fluorescence of an anchored cyanine-based probe that displays restricted intramolecular rotation (RIR)-induced emission. This label-free system can be used as a sensor for mercury ions with a detection limit of 4 nM.
Laboratory of Nanomedicine and Nanosafety, Division of Nanomedicine and Nanobiology, National Center for Nanoscience and Technology of China, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Chinese Academy of Sciences, Beijing, 100190, China. zougz@nanoctr.cn liangxj@nanoctr.cn.
Shengliang
S
Li
Hua
H
Deng
Weipeng
W
Cao
Chunqiu
C
Zhang
Shubin
S
Jin
Xiangdong
X
Xue
Jinchao
J
Zhang
Feng
F
Li
Guozhang
G
Zou
Xing-Jie
XJ
Liang
D002232:Carbocyanines / Q000737:chemistry*; D002413:Cations, Divalent / Q000737:chemistry; D004277:DNA, Single-Stranded / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D057230:Limit of Detection; D008628:Mercury / Q000032:analysis*; D008958:Models, Molecular; D013050:Spectrometry, Fluorescence / Q000379:methods; D013941:Thymine / Q000737:chemistry*
D002232:Carbocyanines; D002413:Cations, Divalent; D004277:DNA, Single-Stranded; D005456:Fluorescent Dyes; D008628:Mercury; D013941:Thymine