Volatile oils from the aerial parts of Eremophila maculata and their antimicrobial activity.
The essential oils isolated from the fresh flowers, fresh leaves, and both fresh and air-dried stems of Eremophila maculata (Scrophulariaceae) were characterized by GC-FID and GC/MS analyses. Sabinene was the major component in most of the oils, followed by limonene, α-pinene, benzaldehyde, (Z)-β-ocimene, and spathulenol. The leaf and flower essential oils showed antibacterial and antifungal activity against five Gram-positive and four Gram-negative bacterial strains, multi-resistant clinical isolates from patients, i.e., methicillin-resistant Staphylococcus aureus (MRSA), as well as two yeasts. Minimum inhibitory concentrations (MICs) and minimum microbicidal concentrations (MMCs) were between 0.25 and 4 mg/ml.
Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Abbassia, 11566-Cairo, Egypt.
Fadia S
FS
Youssef
Razan
R
Hamoud
Mohamed L
ML
Ashour
Abdel Nasser
AN
Singab
Michael
M
Wink
D000890:Anti-Infective Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy; D000081008:Bicyclic Monoterpenes; D005658:Fungi / Q000187:drug effects; D006801:Humans; D039821:Monoterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D009181:Mycoses / Q000188:drug therapy; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D035261:Plant Components, Aerial / Q000737:chemistry*; D028083:Scrophulariaceae / Q000737:chemistry*
D000890:Anti-Infective Agents; D000081008:Bicyclic Monoterpenes; D039821:Monoterpenes; D009822:Oils, Volatile; C035127:sabinene
Antimicrobial activity; Eremophila maculata; Essential oils; Sabinene