EndoGlide versus EndoSerter for the insertion of donor graft in descemet stripping automated endothelial keratoplasty.
OBJECTIVE
To compare 2 lenticule insertion methods currently in use for Descemet stripping automated endothelial keratoplasty (DSAEK).


METHODS
Prospective randomized single-masked study.


METHODS
Twenty patients with Fuchs endothelial dystrophy and pseudophakic bullous keratopathy undergoing DSAEK surgery were included and randomized to the use of either EndoGlide or EndoSerter as a delivery method for the donor lenticule. Post surgery, patients were monitored for up to 1 year. Evaluation included corrected distance visual acuity (CDVA) and refraction. Specular microscopy images were obtained at the 6- and 12-month visits. Complications, including rebubbling rate, graft dislocation, and graft failure, were recorded.


RESULTS
Twenty eyes were randomized to receive the Tan EndoGlide or the EndoSerter injector for lenticule insertion. Mean patient age was 65.9±8.4 years and 70.3±9.8 years in the Tan EndoGlide and EndoSerter groups, respectively (P=.3). Two eyes in each group needed rebubbling. The mean endothelial cell loss, including the rebubbled eyes, at the 12-month visit was 1093±629 cells/mm2 (range: 239-2109 cells/mm2, mean percentage cell loss 41.2%) and 877±566 cells/mm2 (range: 116-1851 cells/mm2, mean percentage cell loss 31.4%) in the Tan EndoGlide and EndoSerter groups, respectively (P=.45). Mean CDVA did not show a statistically significant difference between the 2 groups at the 6- or 12-month visit.


CONCLUSIONS
The EndoSerter shows comparable results to the Tan EndoGlide. However, further investigation is warranted in order to validate these findings.
Department of Ophthalmology and Vision Sciences, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada. Electronic address: urielbaz@gmail.com.
Uri
U
Elbaz
Department of Ophthalmology and Vision Sciences, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.
Sonia N
SN
Yeung
Department of Ophthalmology and Vision Sciences, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.
Alejandro
A
Lichtinger
Department of Ophthalmology and Vision Sciences, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.
Noa Avni
NA
Zauberman
Department of Ophthalmology and Vision Sciences, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.
Yakov
Y
Goldich
Department of Ophthalmology and Vision Sciences, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.
Setareh
S
Ziai
Department of Ophthalmology and Vision Sciences, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.
Clara C
CC
Chan
Department of Ophthalmology and Vision Sciences, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.
David S
DS
Rootman
Department of Ophthalmology and Vision Sciences, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.
Allan R
AR
Slomovic
D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber / Q000601:surgery; D003886:Descemet Membrane / Q000601:surgery*; D057111:Descemet Stripping Endothelial Keratoplasty / Q000295:instrumentation*; D004728:Endothelium, Corneal / Q000637:transplantation*; D004867:Equipment Design; D005260:Female; D005500:Follow-Up Studies; D005642:Fuchs' Endothelial Dystrophy / Q000503:physiopathology / Q000601:surgery*; D006085:Graft Survival; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016037:Single-Blind Method; D016896:Treatment Outcome; D014792:Visual Acuity