Multiple simple bone cysts of the jaws: review of the literature and report of three cases.
OBJECTIVE
This study contributes three well-documented cases of multiple simple bone cysts (SBCs) of the jaws and reviews previously published cases.


METHODS
A comprehensive literature search of multiple SBCs was conducted using the PubMed database. Synonyms of SBC were used as search key words in combination with "mandible or jaw," "bilateral, multiple, multifocal, atypical, and unusual."


RESULTS
A total of 34 cases of multiple SBCs (including two asynchronous cases) were identified, including the three new cases reported here. Multiple SBCs primarily occurred in the second decade (52.9%) and bilaterally in the posterior mandible. Lesions demonstrated female predominance (1.8:1) and were frequently accompanied by bony expansion (44.1%) and a multilocular radiolucent appearance (20.6 %). Recurrence was reported in three patients (mean age: 39.3 years old).


CONCLUSIONS
Knowledge of the clinical and radiographic features of multiple SBCs is important in the diagnosis and management of this entity.
Assistant Professor, Department of Oral and Maxillofacial Radiology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea.
Seo-Young
SY
An
Assistant Professor, Department of Oral and Maxillofacial Radiology, School of Dentistry, Dental Science Institute, Chonnam National University, Gwangju, Republic of Korea.
Jae-Seo
JS
Lee
Clinical Assistant Professor, Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Erika
E
Benavides
Adjunct Lecturer, Division of Endodontics, University of Michigan, Ann Arbor, Michigan and Specialist Endodontic Private Practice, Farmington Hills, Michigan, USA.
Alireza
A
Aminlari
Clinical Professor, Division Head and Graduate Program Director, Endodontics, University of Michigan, Ann Arbor, Michigan, USA.
Neville J
NJ
McDonald
Professor, Department of Oral Pathology, Medicine and Radiology, Indiana University School of Dentistry, Indianapolis, Indiana, USA.
Paul C
PC
Edwards
Professor, Department of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
Min-Suk
MS
Heo
Associate Professor, Department of Oral Pathology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea.
Hong-In
HI
Shin
Assistant Professor, Department of Periodontology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea.
Jin-Woo
JW
Park
Assistant Professor, Department of Oral Medicine, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea.
Jae-Kwang
JK
Jung
Professor, Department of Oral and Maxillofacial Radiology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea. Electronic address: ksichoi@knu.ac.kr.
Karp-Shik
KS
Choi
Associate Professor, Department of Oral and Maxillofacial Radiology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea. Electronic address: chan@knu.ac.kr.
Chang-Hyeon
CH
An
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002648:Child; D054893:Cone-Beam Computed Tomography; D005260:Female; D006801:Humans; D007570:Jaw Cysts / Q000000981:diagnostic imaging* / Q000601:surgery*; D008297:Male; D011862:Radiography, Panoramic