O-acetylation of low-molecular-weight polysaccharide from Enteromorpha linza with antioxidant activity.
Polysaccharide extracted from green algae Enteromorpha linza (EP) is a sulfated polysaccharide, which possesses excellent antioxidant activities. In present study, the acetylated derivatives of low-molecular-weight polysaccharide (LEP) was prepared with the method of response surface quadratic model. And then the antioxidant activities of the derivatives were investigated including scavenging effects of superoxide and hydroxyl radicals. The results of chemical analysis and FT-IR spectrum showed the acetylation was successful. And in addition, certain derivative with different degree of substitution (DS) exhibited different antioxidant activity.
Department of Pharmacology, Huzhou Teachers College, Huzhou 313000, China. Electronic address: zhzs@hutc.zj.cn.
Zhongshan
Z
Zhang
Department of Pharmacology, Huzhou Teachers College, Huzhou 313000, China.
Xiaomei
X
Wang
Department of Pharmacology, Huzhou Teachers College, Huzhou 313000, China.
Mingxing
M
Zhao
School of Pharmaceutical and Biological Sciences, Weifang Medical University, Weifang 261053, China.
Huimin
H
Qi
D019342:Acetic Acid / Q000737:chemistry; D000107:Acetylation; D016166:Free Radical Scavengers / Q000737:chemistry* / Q000494:pharmacology*; D017665:Hydroxyl Radical / Q000737:chemistry; D008970:Molecular Weight; D011134:Polysaccharides / Q000737:chemistry* / Q000494:pharmacology*; D012995:Solubility; D012997:Solvents / Q000737:chemistry; D013329:Structure-Activity Relationship; D013481:Superoxides / Q000737:chemistry; D044445:Ulva / Q000737:chemistry*; D014783:Viscosity; D014867:Water / Q000737:chemistry
D016166:Free Radical Scavengers; D011134:Polysaccharides; D012997:Solvents; D014867:Water; D013481:Superoxides; D017665:Hydroxyl Radical; D019342:Acetic Acid
Acetylation; Antioxidant activities; Enteromorpha linza