A pyogenic granuloma treated with topical timolol.
Pyogenic granulomas are benign vascular tumours usually surgically treated by excision or curettage. The only topical therapy reported to date is imiquimod 5% cream but it produces a marked inflammatory response with discomfort generally worse than simple surgical excision or curettage. Here we report the use of timolol 0·5% ophthalmic gel used successfully to treat a teenager with a clinically classical pyogenic granuloma on the finger. There were no reported adverse effects and the lesion completely resolved. It has not recurred after 7 months. Timolol may be an effective and preferable alternative treatment to surgery for a classical small pyogenic granuloma, particularly in children and young people.
Department of Dermatology, Queens Medical Centre, Nottingham University Hospital, Nottingham, NG7 2UH, U.K.
M
M
Malik
R
R
Murphy
D000279:Administration, Cutaneous; D000293:Adolescent; D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage*; D005385:Fingers; D005782:Gels; D017789:Granuloma, Pyogenic / Q000188:drug therapy*; D006229:Hand Dermatoses / Q000188:drug therapy*; D006801:Humans; D056687:Off-Label Use; D013999:Timolol / Q000008:administration & dosage*
D000319:Adrenergic beta-Antagonists; D005782:Gels; D013999:Timolol