Laryngeal osteosarcoma: case report and literature review.
BACKGROUND
Sarcomas of the larynx are uncommon tumors, and osteosarcoma is the rarest. Only 24 cases of osteosarcoma of the larynx have been reported. The only case reported in Asia was from Thailand in 1981.


METHODS
A 55-year-old male patient was referred to our hospital because of an 8-month history of odynophagia and a gradually enlarging left neck mass. A neck CT scan was performed. A literature review was also performed for this report.


RESULTS
The CT scan revealed extensive calcification with enlargement of the thyroid cartilage. The patient was diagnosed with osteosarcoma and was successfully treated by surgery alone.


CONCLUSIONS
Adequate surgical resection is required for successful treatment of laryngeal sarcomas. Adjuvant therapy is not contraindicated, but chemotherapy may improve the prognosis in patients with high-grade tumors or metastatic disease.
Department of Head and Neck Surgery and Otolaryngology, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
Kiyomi
K
Kuba
Hitoshi
H
Inoue
Takahiro
T
Hayashi
Satoko
S
Matsumura
Kazuhiko
K
Minami
Humihiko
H
Takajo
Kei
K
Morita
Mitsuhiko
M
Nakahira
Masashi
M
Sugasawa
D006801:Humans; D007564:Japan; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012516:Osteosarcoma / Q000473:pathology* / Q000601:surgery; D035583:Rare Diseases / Q000473:pathology
head and neck; hoarseness; laryngeal osteosarcoma; odynophagia; thyroid cartilage