The role of the anterior insula in adolescent decision making.
Much recent research on adolescent decision making has sought to characterize the neurobiological mechanisms that underlie the proclivity of adolescents to engage in risky behavior. One class of influential neurodevelopmental models focuses on the asynchronous development of neural systems, particularly those responsible for self-regulation and reward seeking. While this work has largely focused on the development of prefrontal (self-regulation) and striatal (reward processing) circuitry, the present article explores the significance of a different region, the anterior insular cortex (AIC), in adolescent decision making. Although the AIC is known for its role as a cognitive-emotional hub, and is included in some models of adult self-regulation and reward seeking, the importance of the AIC and its maturation in adolescent risk taking has not been extensively explored. In this article we discuss evidence on AIC development, and consider how age-related differences in AIC engagement may contribute to heightened risk taking during adolescence. Based on this review, we propose a model in which the engagement of adolescents in risk taking may be linked in part to the maturation of the AIC and its connectivity to the broader brain networks in which it participates.
Department of Psychology, Temple University, Philadelphia, Pa., USA.
Ashley R
AR
Smith
Laurence
L
Steinberg
Jason
J
Chein
D000293:Adolescent; D000294:Adolescent Behavior / Q000502:physiology*; D002540:Cerebral Cortex / Q000502:physiology*; D003657:Decision Making; D006801:Humans; D012201:Reward; D012309:Risk-Taking