Ru-catalyzed branched versus linear selective C3-alkylation of 2-aroylbenzofurans with acrylates via C-H activation.
The carbonyl-directed C3-H activation and alkylation of 2-aroylbenzo[b]furans with acrylates occurs selectively either in a linear or branched fashion, depending on the catalyst employed; [Ru(p-cymene)Cl2]2 or Ru(PPh3)3Cl2, respectively. Two alternate pathways--funded upon the differences in steric and electronic preferences of these two complexes--is proposed for the selectivity of linear versus branched products.
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Yadagiri
Y
Kommagalla
Kolluru
K
Srinivas
Chepuri V
CV
Ramana
CH activation; acrylate; benzo[b]furan; branched-selective alkylation; ruthenium