Case of emphysematous cholecystitis in a patient with type 2 diabetes mellitus associated with schizophrenia.
Emphysematous cholecystitis is a rare, but life-threatening, form of acute cholecystitis caused by gas-forming organisms in the gallbladder. A 73-year-old male patient with type 2 diabetes mellitus complicated with neuropathy associated with schizophrenia was admitted to Okayama University Hospital, Okayama, Japan, because of a high fever and general malaise. On the fourth hospital day, despite normal liver function tests and little abdominal pain, his abdominal computed tomography showed huge gas formation in the gallbladder lumen along with a dilated gallbladder with a thickened wall, consistent with emphysematous cholecystitis. The patient underwent an emergency open cholecystectomy. Few abdominal symptoms appeared because of the hyposensitivity to pain caused by not only diabetic neuropathy, but also antipsychotic agents the patient was taking for schizophrenia. Emphysematous cholecystitis should be taken into consideration for the differential diagnosis of high fever in diabetic patients with schizophrenia, irrespective of the level of liver function tests and clinical symptoms.
Department of Medicine and Clinical Science Okayama Japan.
Ayu
A
Ogawa
Department of Medicine and Clinical Science Okayama Japan ; Center for Innovative Clinical Medicine Okayama University Hospital Okayama Japan.
Kenichi
K
Shikata
Department of Medicine and Clinical Science Okayama Japan.
Haruhito Adam
HA
Uchida
Department of Gastroenterological Surgery Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan.
Susumu
S
Shinoura
Department of Gastroenterological Surgery Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan.
Naosuke
N
Yokomichi
Department of Medicine and Clinical Science Okayama Japan.
Daisuke
D
Ogawa
Department of Medicine and Clinical Science Okayama Japan.
Chicage
C
Sato-Horiguchi
Department of Gastroenterological Surgery Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan.
Takahito
T
Yagi
Department of Medicine and Clinical Science Okayama Japan.
Jun
J
Wada
Department of Medicine and Clinical Science Okayama Japan.
Hirofumi
H
Makino
Emphysematous cholecystitis; Schizophrenia; Type 2 diabetes mellitus