Myoglobinuria masquerading as acute rejection in a renal allograft recipient with recurrent post transplant diabetic nephropathy.
Rhabdomyolysis contributes to 7-10% of total AKI cases. Myoglobinuria as a cause of acute renal allograft dysfunction is extremely uncommon. Renal allograft recipient on cyclosporine or tacrolimus can develop myoglobinuria in presence of other precipitating factors. Present case describes an interesting report of myoglobinuria in a patient with post transplant diabetic nephropathy mimicking acute graft rejection. Clinically myoglobinuria presenting as renal allograft dysfunction is diagnosis of exclusion and renal biopsy is extremely important in making a correct diagnosis and planning optimal management in such cases.
Department of Pathology and.
Pallav
P
Gupta
Amit
A
Sharma
Dinesh
D
Khullar
D000368:Aged; D064591:Allografts; D003928:Diabetic Nephropathies / Q000150:complications* / Q000473:pathology; D003937:Diagnosis, Differential; D006084:Graft Rejection / Q000175:diagnosis*; D006801:Humans; D007668:Kidney / Q000473:pathology; D016030:Kidney Transplantation; D008297:Male; D009212:Myoglobinuria / Q000175:diagnosis* / Q000209:etiology; D011183:Postoperative Complications / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D012206:Rhabdomyolysis / Q000150:complications*
Graft dysfunction; rhabdomyolysis; tacrolimus