Molecular watchdogs on genome patrol.
By removing various obstacles from single strands of DNA, an enzyme called Pif1 clears the way for other enzymes that act on DNA.
Gheorghe Chistol is in the Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, United States gheorghe_chistol@hms.harvard.edu.
Gheorghe
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Chistol
Johannes Walter is an eLife reviewing editor, and is in the Howard Hughes Medical Institute and the Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, United States johannes_walter@hms.harvard.edu.
Johannes
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Walter
D004265:DNA Helicases / Q000502:physiology*; D004271:DNA, Fungal / Q000502:physiology*; D012441:Saccharomyces cerevisiae / Q000502:physiology*; D029701:Saccharomyces cerevisiae Proteins / Q000502:physiology*
D004271:DNA, Fungal; D029701:Saccharomyces cerevisiae Proteins; D004265:DNA Helicases
DNA helicases; G-quadruplexes; Pif1 family helicases; R-loops; single molecule analysis