[Value of strain means of quantitative parameters in diagnosis of liver fibrosis].
OBJECTIVE
To explore the value of the strain means of the quantitative parameters of organization diffusion in determining the degree of liver fibrosis.


METHODS
A total of 130 patients with chronic hepatitis B were examined for quantitative analysis of organization diffusion before liver biopsy to analyze the performance of the strain means in liver fibrosis of different degrees. All the cases were confirmed by pathology.


RESULTS
The strain means differed significantly between different stages of liver fibrosis. Using the best cut-off values of 116.2, 111.4, 101.6 and 97.5 for diagnosis of S≥1, S≥2, S≥3 and S=4, the diagnostic sensitivities were 91.2%, 90.8%, 95.8% and 89.7%, with specificities of 90.4%, 98.6%, 93.8% and 95.6% and accuracies of 90.6%, 94.7%, 95.5% and 91.8%, respectively.


CONCLUSIONS
The strain mean can provide specific numerical indicators to determine the degree of liver fibrosis.
Department of Ultrasound, Gangdong General Hospital, Guangdong Academy of Medical, Guangzhou, 510080 China. E-mail: zhoulif21@163.com.
Lifeng
L
Zhou
Shuzhen
S
Cong
Shufang
S
Pei
Yuefeng
Y
Chen
Ruili
R
Zhou
D001706:Biopsy; D004058:Diffusion; D019694:Hepatitis B, Chronic; D006801:Humans; D008103:Liver Cirrhosis / Q000175:diagnosis*; D012680:Sensitivity and Specificity