Fecal microbiota transplantation in children with recurrent Clostridium difficile infection.
Clostridium difficile eradication using fecal microbiota transplantation (FMT) has been successful in adults but little information is available in pediatrics. We report 6 pediatric patients with refractory C. difficile cured by FMT with no recurrences to date. Our results demonstrate that FMT can be an effective treatment for refractory C. difficile infection in pediatrics. Long-term safety and efficacy need to be studied.
From the Columbia University Medical Center, Division of Pediatric Gastroenterology, Hepatology and Nutrition, New York, NY.
Anne
A
Pierog
Ali
A
Mencin
Norelle Rizkalla
NR
Reilly
D001691:Biological Therapy / Q000379:methods; D002648:Child; D002675:Child, Preschool; D016360:Clostridioides difficile; D004761:Enterocolitis, Pseudomembranous / Q000628:therapy*; D005243:Feces / Q000382:microbiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D064307:Microbiota; D012008:Recurrence; D019233:Retreatment; D055815:Young Adult