Nanobiosensing Using Plasmonic Nanoprobes.
This paper provides an overview of the development and applications of plasmonics-active nanoprobes in biomedical diagnostics. Specific examples of detection techniques using surface-enhanced Raman scattering are presented to illustrate the usefulness and potential of the plasmonics nanoprobes for gene detection and nanobiosensing. The detection of specific target deoxyribonucleic acids sequences using a novel "molecular sentinel" nanoprobe method is presented and discussed in detail.
Fitzpatrick Institute for Photonics, Departments of Biomedical Engineering and Chemistry, Duke University, Durham NC 27708 USA.
Tuan
T
Vo-Dinh
Gene diagnostics; Raman; metallic nanostructures; nanoprobes; near-field detection; plasmonics; surface-enhanced Raman scattering (SERS)