Antibiotics from myxobacteria.
Covering: up to the end of 2013. Myxobacteria produce a vast range of structurally diverse natural products with prominent biological activities. Here, we provide a detailed description and judge the potential of all antibiotically active myxobacterial compounds as lead structures, pointing out their particularities and, if known, their mode of action. Thus, the review provides an overview of the potential of specific compounds, suitable for future investigations and possible clinical applications.
Institute for Pharmaceutical Biology, University of Bonn, Nussallee 6, 53115 Bonn, Germany. till.schaeberle@uni-bonn.de g.koenig@uni-bonn.de.
Till F
TF
Schäberle
Friederike
F
Lohr
Alexander
A
Schmitz
Gabriele M
GM
König
D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D051379:Mice; D015394:Molecular Structure; D009231:Myxococcales / Q000737:chemistry / Q000378:metabolism; D051381:Rats
D000900:Anti-Bacterial Agents