Is there any relationship between adverse pregnancy outcome and first trimester nuchal translucency measurements in normal karyotype fetuses?
OBJECTIVE
This study aims to research whether there is a relationship between first trimester nuchal translucency (NT) measurements and pregnancy complications such as gestational diabetes mellitus (GDM), gestational hypertension (GHT), intrauterine growth restriction (IUGR) and oligohydramnios.


METHODS
This study included 225 singleton pregnancies attending Canakkale Onsekiz Mart University Obstetrics and Gynecology clinic for all monitoring and examinations, and gave birth at our clinic between January 2011 and December 2012. Data sources were clinical records and the hospital's automation system, and the study was planned as retrospective cohort. NT measurement was made between 10 weeks 3 days and 13 weeks 6 days gestation. For data analysis, the chi-square, Mann-Whitney U test and Spearman correlation were used.


RESULTS
Of pregnancies, in the study, 5 (2.2%) developed GDM, 6 (2.6%) developed GHT, 2 (0.89%) developed IUGR and 10 (4.4%) developed oligohydramnios. There was no correlation identified between NT measurements and development of GDM, GHT, IUGR and oligohydramnios.


CONCLUSIONS
There was no relationship found between first trimester NT measurements and complications that could develop in pregnancy. For the first time in the literature, NT and oligohydramnios were studied and no relationship was observed.
Department of Radiology .
Fatma
F
Uysal
Emine
E
Coşar
Kaya
K
Yücesoy
Meryem
M
Gencer
Sibel
S
Cevizci
Ayşenur
A
Güngör
Servet
S
Hacıvelioğlu
Ahmet
A
Uysal
D000328:Adult; D005260:Female; D005865:Gestational Age; D006801:Humans; D059785:Karyotype; D048208:Nuchal Translucency Measurement / Q000706:statistics & numerical data; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology; D011261:Pregnancy Trimester, First; D012372:ROC Curve; D012189:Retrospective Studies; D016216:Ultrasonography, Prenatal
Adverse pregnancy outcome; IUGR; gestational diabetes; gestational hypertension; nuchal translucency; oligohydramnios