A tetraphenylethene-based zinc complex as a sensitive DNA probe by coordination interaction.
We developed a new DNA probe by utilizing the coordination interaction of Zn(2+) with DNA and the consequent emission. Because the coordination interactions do not depend on the length of the DNA, the new probe exhibited much higher sensitivity for the detection of short ssDNA than the corresponding probe based on electrostatic interactions.
Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Hubei Key Lab on Organic and Polymeric Optoelectronic Materials, Department of Chemistry, Wuhan University, Wuhan, 430072, People's Republic of China. clyang@whu.edu.cn.
Zece
Z
Zhu
Li
L
Xu
Hao
H
Li
Xiang
X
Zhou
Jingui
J
Qin
Chuluo
C
Yang
D004247:DNA / Q000737:chemistry; D015342:DNA Probes / Q000737:chemistry*; D004277:DNA, Single-Stranded / Q000737:chemistry; D005456:Fluorescent Dyes; D009841:Oligonucleotides / Q000737:chemistry; D011725:Pyridines / Q000737:chemistry*; D055672:Static Electricity; D013267:Stilbenes / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
D015342:DNA Probes; D004277:DNA, Single-Stranded; D005456:Fluorescent Dyes; D009841:Oligonucleotides; D011725:Pyridines; D013267:Stilbenes; D004247:DNA; D015032:Zinc