Regression of peripapillary choroidal neovascular membrane in a patient with sarcoidosis after oral steroid therapy.
Choroidal neovascular membrane (CNV) may occur in patients with posterior uveitis. Treatment of patients with corticosteroids induces regression of the inflammation in the posterior pole with downregulation of many cytokines including vascular endothelial growth factors. We report herewith, a case of biopsy proven sarcoidosis that developed posterior uveitis and peripapillary CNV membrane and subretinal hemorrhage with fluid. The patient was treated with systemic steroids. She demonstrated progressive regression of the CNV membrane and complete resolution of the subretinal hemorrhage and fluids. In conclusion, control of the posterior segment inflammation is crucial in the resolution of the CNV membrane in uveitis and the intravitreal anti-vascular endothelial growth factor may not be always indicated.
The Eye Center and The Eye Foundation for Research in Ophthalmology, Riyadh, Saudi Arabia.
Samir S
SS
Shoughy
The Eye Center and The Eye Foundation for Research in Ophthalmology, Riyadh, Saudi Arabia.
Mahmoud O
MO
Jaroudi
The Eye Center and The Eye Foundation for Research in Ophthalmology, Riyadh, Saudi Arabia ; Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia ; The Wilmer Ophthalmological Institute of The Johns Hopkins University, School of Medicine, Baltimore, MD, USA.
Khalid F
KF
Tabbara
Oral steroids; Peripapillary CNV; Sarcoidosis