Extramedullary pulmonary hematopoiesis causing pulmonary hypertension and severe tricuspid regurgitation detected by technetium-99m sulfur colloid bone marrow scan and single-photon emission computed tomography/CT.
Extramedullary pulmonary hematopoiesis is a rare entity with a limited number of case reports in the available literature only. We report the case of a 66-year-old man with known primary myelofibrosis, in whom a Technetium-99m sulfur colloid bone marrow scan with single-photon emission computed tomography (SPECT)/CT revealed a pulmonary hematopoiesis as the cause of pulmonary hypertension and severe tricuspid regurgitation. To the best of our knowledge, this is the first description of Technetium-99m sulfur colloid SPECT/CT imaging in this rare condition.
Department of Diagnostic Radiology, Khoo Teck Puat Hospital, Singapore 768828, Republic of Singapore.
Syed Zama
SZ
Ali
Department of Diagnostic Radiology, Khoo Teck Puat Hospital, Singapore 768828, Republic of Singapore.
Michael John
MJ
Clarke
Department of Diagnostic Radiology, Khoo Teck Puat Hospital, Singapore 768828, Republic of Singapore.
Anbalagan
A
Kannivelu
Department of Diagnostic Radiology, Khoo Teck Puat Hospital, Singapore 768828, Republic of Singapore.
Dinesh
D
Chinchure
Department of Diagnostic Radiology, Khoo Teck Puat Hospital, Singapore 768828, Republic of Singapore.
Sivasubramanian
S
Srinivasan
D000368:Aged; D001853:Bone Marrow / Q000000981:diagnostic imaging*; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging / Q000209:etiology*; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D055728:Primary Myelofibrosis / Q000150:complications; D013671:Technetium Tc 99m Sulfur Colloid; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods; D014057:Tomography, X-Ray Computed; D014262:Tricuspid Valve Insufficiency / Q000000981:diagnostic imaging / Q000209:etiology*
D013671:Technetium Tc 99m Sulfur Colloid
Extramedullary pulmonary hematopoiesis; Pulmonary hypertension; SPECT/CT; Technetium-99m sulfur colloid bone marrow scan; Tricuspid regurgitation