Deciphering developmental processes from single-cell transcriptomes.
Alveoli facilitate air-blood interchange in the lungs from birth to the last breath. Reporting in Nature, Treutlein et al. (2014) apply single-cell RNA sequencing to the developing mouse lung to address some of the unanswered questions surrounding the embryonic origins of alveoli.
Developmental Cellomics Laboratory, Genome Institute of Singapore, Singapore 138672; Department of Biological Sciences, National University of Singapore, Singapore 117543. Electronic address: robsonp@gis.a-star.edu.sg.
Paul
P
Robson
D000818:Animals; D019070:Cell Lineage / Q000235:genetics*; D004847:Epithelial Cells / Q000166:cytology* / Q000378:metabolism*; D005260:Female; D008168:Lung / Q000166:cytology*; D017423:Sequence Analysis, RNA / Q000379:methods*; D059010:Single-Cell Analysis / Q000379:methods*