Silicon nanowire-based fluorescent nanosensor for complexed Cu2+ and its bioapplications.
A silicon nanowires (SiNWs)-based fluorescent sensor for complexed Cu(2+) was realized. High sensitivity and selectivity of the present sensor facilitate its bioapplications. The sensor was successfully used to detect the Cu(2+) in liver extract. Meanwhile, real-time and in situ monitoring of Cu(2+) released from apoptotic HeLa cell was performed using the as-prepared SiNW arrays-based sensor. These results indicate that the present SiNWs-based sensor would be of potential applications in revealing the physiological and pathological roles of Cu(2+).
Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Beijing, 100190 China.
Rong
R
Miao
Lixuan
L
Mu
Hongyan
H
Zhang
Guangwei
G
She
Bingjiang
B
Zhou
Haitao
H
Xu
Pengfei
P
Wang
Wensheng
W
Shi
D015374:Biosensing Techniques / Q000379:methods*; D003300:Copper / Q000032:analysis* / Q000378:metabolism; D006367:HeLa Cells; D006801:Humans; D053770:Nanowires / Q000737:chemistry*; D012825:Silicon / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
D003300:Copper; D012825:Silicon