Section 1. Image evaluation of fatty liver in living donor liver transplantation.
Preoperative evaluation of donors for living-donor liver transplantation aims to select a suitable donor with optimal graft quality and to ensure donor safety. Hepatic steatosis, a common finding in living liver donors, not only influences the outcome of liver transplantation for the recipient but also affects the recovery of the living donor after partial hepatectomy. Histopathologic analysis is the reference standard to detect and quantify fat in the liver, but it is invasive, and results are vulnerable to sampling error. Imaging can be repeated regularly and allows assessment of the entire liver, thus avoiding sampling error. Selection of appropriate imaging methods demands understanding of their advantages and limitations and the suitable clinical setting. This article describes potential clinical applications for liver fat quantification of imaging methods for fat detection and quantification, with an emphasis on the advantages and limitations of ultrasonography, computed tomography, and magnetic resonance imaging for quantifying liver fat.
1 Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Taiwan. 2 Department of Surgery, Kaohsiung Chang Gung Memorial Hospital, Taiwan. 3 Division of Hepatogastroenterology, Department of Medicine, Kaohsiung Chang Gung Memorial Hospital, Taiwan. 4 Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital, Taiwan. 5 Department of Pathology, Kaohsiung Chang Gung Memorial Hospital, Taiwan. 6 Address correspondence to: Chao-Long Chen, M.D., Liver Transplantation Program and Department of Surgery, Kaohsiung Chang Gung Memorial Hospital, 123 Tai-Pei Road, Niao-Sung, Kaohsiung 83305, Taiwan.
Yu-Fan
YF
Cheng
Chun-Yen
CY
Yu
Hsin-You
HY
Ou
Leo Leung-Chit
LL
Tsang
Tung-Liang
TL
Huang
Tai-Yi
TY
Chen
Allan
A
Concejero
Chih-Chi
CC
Wang
Shih-Ho
SH
Wang
Tsan-Shiun
TS
Lin
Yueh-Wei
YW
Liu
Chin-Hsiang
CH
Yang
Chee-Chien
CC
Yong
King-Wah
KW
Chiu
Bruno
B
Jawan
Hock-Liew
HL
Eng
Chao-Long
CL
Chen
D001208:Asia; D001706:Biopsy; D003952:Diagnostic Imaging / Q000379:methods; D046148:Donor Selection; D005234:Fatty Liver / Q000150:complications / Q000175:diagnosis*; D006498:Hepatectomy; D006801:Humans; D008115:Liver Regeneration; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008279:Magnetic Resonance Imaging; D011237:Predictive Value of Tests; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014463:Ultrasonography