Povidone-iodine-halothane interaction.
A patient with no history of halogen sensitivity, having used povidone-solution previously without adverse effect, developed contact dermatitis when concurrently exposed to Hafothane. The area of dermatitis was localized to those areas on which the povidone-iodine solution was allowed to dry and remained in place while exposed to the Halothane intraoperatively. All symptoms disappeared upon removal of the solution, and did not reoccur upon challenge with povidone-iodine without concurrent exposure to Halothane, or when exposed to Halothane, intraoperatively, without Concurrent exposure to dried povidone-iodine solution.
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Herrick
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Herrick