Current nanotechnological approaches for an effective delivery of bio-active drug molecules in the treatment of acne.
Acne is a chronic inflammatory human skin disease, characterized by areas of skin with seborrhoea, comedones, papules, nodules, pimples, and possibly scarring with lesions occurring on face, neck, and back. Nanotechnological approaches such as particulate (solid lipid nanoparticles and microspheres), vesicular (liposomes and niosomes), colloidal drug delivery systems (micro-emulsion and nano-emulsion), and miscellaneous systems (aerosol foams and micro-sponges) have an important place in acne therapy. These approaches have an enormous opportunity for the designing of a novel, low-dose and effective treatment systems to control acne disease. In this review, we specially focus on the different nanotechnological approaches for an effective treatment of acne.
a Department of Pharmaceutics , ISF College of Pharmacy , Moga, Punjab , India.
Tarun
T
Garg
D000152:Acne Vulgaris / Q000378:metabolism / Q000382:microbiology / Q000473:pathology / Q000628:therapy*; D000726:Androgen Antagonists / Q000627:therapeutic use; D000728:Androgens / Q000096:biosynthesis; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016503:Drug Delivery Systems / Q000379:methods*; D004655:Emulsions; D037741:Fullerenes / Q000627:therapeutic use; D006801:Humans; D008081:Liposomes / Q000737:chemistry / Q000493:pharmacokinetics / Q000627:therapeutic use*; D008863:Microspheres; D053758:Nanoparticles / Q000737:chemistry / Q000627:therapeutic use*; D028321:Plant Preparations / Q000627:therapeutic use; D011425:Propionibacterium acnes / Q000187:drug effects / Q000254:growth & development / Q000472:pathogenicity; D012176:Retinoids / Q000627:therapeutic use; D012629:Sebum / Q000187:drug effects; D012867:Skin / Q000187:drug effects / Q000382:microbiology / Q000473:pathology
D000726:Androgen Antagonists; D000728:Androgens; D000900:Anti-Bacterial Agents; D004655:Emulsions; D037741:Fullerenes; D008081:Liposomes; D028321:Plant Preparations; D012176:Retinoids
Propionibacterium acnes; acne vulgaris; fullerenes; liposomes; micro-sponge