Medical countermeasures after a radiological event: an update from the CATO project.
OBJECTIVE
As part of the European project 'CBRN crisis management: Architecture, Technologies and Operational Procedures' (CATO), an open Toolbox is in development that will address the needs of all stakeholders from first responders to decision makers. A database on chemical, biological, radiological and nuclear (CBRN) threats, including information on medical countermeasures, will be integrated in this Toolbox.


CONCLUSIONS
After a radiological accident, review of national and international recommendations for the major countermeasures (stable iodine, Prussian Blue, and diethylenetriaminepentaacetic acid [DTPA]) showed that discrepancies in treatment protocols and open questions remain: How to proceed in case of repeated release of radioiodines? Which dosage for Prussian Blue? For which radionuclides is DTPA really effective? This paper brings elements to answer these questions.
CEA/DSV/Prositon Route du Panorama, Fontenay-aux-Roses Cedex , Paris Cedex , France.
Alexandra
A
Leiterer
Isabelle
I
Bardot
Florence
F
Ménétrier
Sébastien
S
Bardot
Olivier
O
Grémy
Philippe
P
Bérard
Annick
A
Pech
Pascal
P
Favaro
D000279:Administration, Cutaneous; D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D055885:Biohazard Release / Q000517:prevention & control*; D002648:Child; D002675:Child, Preschool; D016208:Databases, Factual; D003657:Decision Making; D004189:Disaster Planning / Q000379:methods*; D004632:Emergency Medical Services / Q000458:organization & administration; D005060:Europe; D005295:Ferrocyanides / Q000627:therapeutic use*; D006801:Humans; D019570:Inhalation Exposure; D007455:Iodine / Q000737:chemistry* / Q000627:therapeutic use; D008875:Middle Aged; D004369:Pentetic Acid / Q000737:chemistry; D011829:Radiation Dosage; D018788:Radioactive Hazard Release / Q000517:prevention & control
D005295:Ferrocyanides; D004369:Pentetic Acid; D007455:Iodine; C000170:ferric ferrocyanide
Blue; CBRN; DTPA; Internal contamination; Prussian; decorporation treatment; guidelines; stable iodine