Is there association between ABO blood group and the risk factors of unfavorable outcomes of pregnancy?
There are four major blood groups in human based on the presence of A and B antigens. ABO gene encodes A and B antigens on the surface of red blood cells and there are reported relations between this blood phenotype and pregnancy outcomes in the women. In this study, medical records of 792 healthy pregnant women were investigated and their age and blood test results including blood group with fasting blood sugar, hemoglobin, hematocrit, urea, creatinine and red blood cell counts were analyzed in statistical package for the social sciences. The RBC count in AB blood type was significantly higher than A and O blood group, also FBS level in the people with AB blood group was meaningfully higher than A group. But the mean of HGB and HCT were not significantly different between groups. The serum urea in the AB group was higher than the three other groups and also it was significantly higher in B compared to O and A blood groups. The serum creatinine in the AB group was higher than the three other groups too. Also it was significantly higher in the B group compared to A blood groups. These results indicate that the ABO blood group may have association with some of the risk factors of the unfavorable outcomes of pregnancy and it may be one of the prognostic tools, also it addresses more extensive studies.
Immunology Research Center, Tabriz University of Medical Sciences , Tabriz , Iran .
Nayer
N
Seyfizadeh
Narges
N
Seyfizadeh
Bahman
B
Yousefi
Sajad
S
Borzoueisileh
Maryam
M
Majidinia
Dariush
D
Shanehbandi
Mohammad Ali
MA
Jahani
D000017:ABO Blood-Group System / Q000009:adverse effects; D000328:Adult; D004906:Erythrocyte Count; D004912:Erythrocytes / Q000737:chemistry; D005260:Female; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D012307:Risk Factors; D055815:Young Adult
D000017:ABO Blood-Group System; D006454:Hemoglobins
ABO blood group; anemia; gestational diabetes; hypertensive disorders; pregnancy