[Comparison of the therapeutic effect on skeletal fluorosis and impact on urine fluoride value among fire needle therapy, electroacupuncture and calcium carbonate D3].
OBJECTIVE
To observe the impacts on skeletal fluorosis pain, joint motor dysfunction and urine fluoride excretion in the treatment with fire needle therapy, electroacupuncture and calcium carbonate D3.


METHODS
The randomized controlled trial was adopted. Ninety-five patients were randomized into a fire needle group (31 cases), an electroacupuncture group (33 cases) and a calcium carbonate D3 group (31 cases). In the fire needle group and the electroacupuncture group, Ashi points, Dazhui (GV 14), Geshu (BL 17), Quchi (LI 11), Hegu (LI 4), Xuehai (SP 10) points were selected and stimulated with fire needle and electroacupuncture separately, three times a week. In the calcium carbonate D3 group, calcium carbonate D3 tablets was prescribed for oral administration, 600 mg each time, twice a day. The duration of treatment was 2 months in the electroacupuncture group and calcium carbonate D3 group and 1 month in the fire needle group. VAS score, the range of motion (ROM) and urine fluoride value were compared before and after treatment in the patients of the three groups.


RESULTS
After treatment, VAS value and ROM were improved significantly in the patients of the three groups (all P < 0.05), the difference was not significant in comparison of the three groups (all P > 0.05). After treatment, the urine fluoride value was increased significantly in the fire needle group [(7.89 +/- 3.61) mg/L vs (9.81 +/- 4.17) mg/L, P < 0.01] and was increased in the electroacupuncture group [(7.53 +/- 3.46) mg/L vs (8.97 +/- 4.21) mg/L, P < 0.05]. The difference was not significant in comparison before and after treatment in the calcium carbonate D3 group (P > 0.05).


CONCLUSIONS
The fire needle therapy, electroacupuncture and calcium carbonate D3 all have the clinical value in the prevention and treatment of skeletal fluorosis and the difference in the therapeutic effect has not been discovered among them yet at present. But it has been found that the fire needle therapy and electroacupuncture display the active significance in the promotion of urine fluoride excretion.
Tong
T
Wang
Xu-Guang
XG
Yang
Zhong-Chao
ZC
Wu
Jin-Cao
JC
Zhou
Zhong-Jie
ZJ
Chen
Jing
J
Hu
Yue
Y
Jiao
Xiao-Guang
XG
Zhao
D000328:Adult; D000368:Aged; D001847:Bone Diseases / Q000188:drug therapy / Q000628:therapy* / Q000652:urine; D002119:Calcium Carbonate / Q000008:administration & dosage*; D015671:Electroacupuncture / Q000295:instrumentation; D005260:Female; D005459:Fluorides / Q000652:urine*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009339:Needles; D016896:Treatment Outcome
D002119:Calcium Carbonate; D005459:Fluorides