Tadpole tail regeneration in Xenopus.
Some organisms have a remarkable ability to heal wounds without scars and to regenerate complex tissues following injury. By gaining a more complete understanding of the biological mechanisms that promote scar-free healing and tissue regeneration, it is hoped that novel treatments that can enhance the healing and regenerative capacity of human patients can be found. In the present article, we briefly examine the genetic, molecular and cellular mechanisms underlying the regeneration of the Xenopus tadpole tail.
Yaoyao
Y
Chen
Nick R
NR
Love
*The Healing Foundation Centre, Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, U.K.
Enrique
E
Amaya
D000818:Animals; D015870:Gene Expression; D008954:Models, Biological; D017382:Reactive Oxygen Species / Q000378:metabolism; D012038:Regeneration; D013623:Tail / Q000502:physiology*; D014981:Xenopus / Q000235:genetics / Q000502:physiology*
D017382:Reactive Oxygen Species