Monodisperse lanthanide oxyfluorides LnOF (Ln = Y, La, Pr-Tm): morphology controlled synthesis, up-conversion luminescence and in vitro cell imaging.
Lanthanide oxyfluorides LnOF (Ln = Y, La, Pr-Tm) nano/micro-materials with a variety of well-defined morphologies including nanorods, nanospindles, nanorod-bundles and nanospheres, have been successfully synthesized via a facile precipitation technique followed by a heating treatment. It is found that the pH values, fluoride sources and dosage of urea in the initial reaction systems play critical roles in the morphology determination of the LnOF products and the possible formation mechanism for these diverse architectures has been presented. XRD, FT-IR, TG-DTA, SEM, TEM, as well as up-conversion (UC) luminescence spectra are used to characterize the synthesized samples. Under 980 nm NIR laser excitation, red, green and blue UC luminescence are observed from Yb(3+)/Er(3+), Yb(3+)/Ho(3+) and Yb(3+)/Tm(3+) co-doped YOF nanospheres. The MTT assay indicates that YOF nanospheres exhibit good biocompatibility. Especially, the emission spectrum of YOF: 0.20Yb(3+), 0.04Er(3+) nanospheres is dominated by a single red emission at 660 nm, which falls into the "optical window" of biological tissues. The application of YOF: 0.20Yb(3+), 0.04Er(3+) nanospheres in the cell imaging is also investigated, which shows a bright-red emission without background noise.
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, P.R. China. jlin@ciac.ac.cn zyhou@ciac.ac.cn.
Yang
Y
Zhang
Xuejiao
X
Li
Zhiyao
Z
Hou
Jun
J
Lin
D016475:3T3 Cells; D000818:Animals; D003287:Contrast Media / Q000138:chemical synthesis; D005461:Fluorine; D028581:Lanthanoid Series Elements / Q000138:chemical synthesis; D008163:Luminescent Measurements / Q000379:methods*; D053768:Metal Nanoparticles / Q000737:chemistry / Q000648:ultrastructure*; D051379:Mice; D008856:Microscopy, Fluorescence / Q000379:methods*; D054118:Nanospheres / Q000737:chemistry / Q000648:ultrastructure; D010087:Oxides / Q000138:chemical synthesis; D010316:Particle Size; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D003287:Contrast Media; D028581:Lanthanoid Series Elements; D010087:Oxides; D005461:Fluorine; C014559:fluorine monoxide