Comparative analysis of antibacterial properties and chemical composition of Glycyrrhiza glabra L. from Astrakhan region (Russia) and Calabria region (Italy).
We compared antibacterial activity of various extracts of two licorice subspecies against Staphylococcus aureus, Escherichia coli, and Bacillus subtilis. Diethyl carbonate extracts of Glycyrrhiza glabra root from Astrakhan region (Russia) exhibited maximum activity against the test microbial strains; activity of Astrakhan licorice was superior among 50% ethanol extracts from Astrakhan (Russia) and Calabria (Italy). Antibacterial activity is directly proportional to the content of glycyrrhizin and 18β-glycyrrhetinic acid in the extracts. According to preliminary data, the content of these chemical components in Glycyrrhiza glabra root from Astrakhan region is higher than in licorice growing in Italy, which is presumably related to climate and geographic characteristics of Astrakhan region.
Astrakhan State University, Astrakhan, Russia, astra39@list.ru.
O V
OV
Astaf'eva
L T
LT
Sukhenko
D000900:Anti-Bacterial Agents / Q000032:analysis / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects; D004047:Diethyl Pyrocarbonate / Q000031:analogs & derivatives; D004926:Escherichia coli / Q000187:drug effects; D000431:Ethanol; D006034:Glycyrrhetinic Acid / Q000031:analogs & derivatives / Q000737:chemistry / Q000494:pharmacology; D006035:Glycyrrhiza / Q000737:chemistry* / Q000235:genetics; D019695:Glycyrrhizic Acid / Q000737:chemistry / Q000494:pharmacology; D007558:Italy; D015394:Molecular Structure; D010936:Plant Extracts / Q000032:analysis* / Q000494:pharmacology; D018517:Plant Roots / Q000737:chemistry*; D012426:Russia; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D010936:Plant Extracts; C119129:18alpha-glycyrrhetinic acid; D000431:Ethanol; C017858:ethyl carbonate; D019695:Glycyrrhizic Acid; D004047:Diethyl Pyrocarbonate; D006034:Glycyrrhetinic Acid