Regulative peroxidase activity of DNA-linked hemin by graphene oxide for fluorescence DNA sensing.
The inhibition effect of graphene oxide toward the peroxidase activity of DNA-linked hemin was identified and conveniently utilized in the design of a homogenous fluorescence strategy for DNA sensing with high sensitivity.
State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China. hxju@nju.edu.cn.
Quanbo
Q
Wang
Nan
N
Xu
Jianping
J
Lei
Huangxian
H
Ju
D015374:Biosensing Techniques; D004247:DNA / Q000737:chemistry*; D004277:DNA, Single-Stranded / Q000737:chemistry; D005453:Fluorescence; D006108:Graphite / Q000737:chemistry* / Q000494:pharmacology; D006427:Hemin / Q000737:chemistry*; D010544:Peroxidases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D014439:Tyramine / Q000737:chemistry
D004277:DNA, Single-Stranded; D006427:Hemin; D006108:Graphite; D004247:DNA; D010544:Peroxidases; D014439:Tyramine