Risk of Recurrence of Preexisting Ocular Toxoplasmosis during Pregnancy.
OBJECTIVE
Comparison between the risk of recurrence during pregnancy with nonpregnant periods in patients with ocular toxoplasmosis (OT).


METHODS
Records of 40 women were retrospectively reviewed. The women were subdivided into either a pregnant group or a control group formed by nonpregnant women during follow-up. Comparable cases from the literature were added. Mean number of recurrences per year was compared.


RESULTS
Eleven women with pregnancies could be included. Six cases from the literature were added (total n = 17). Mean number of recurrences per year during versus not during pregnancy was 0.16 (SD 0.39) versus 0.32 (SD 0.30; p = 0.088), respectively. In the control group (n = 29) the mean number of recurrences per year (0.31; SD 0.27) was significantly higher when compared to cases during pregnant periods (p = 0.002).


CONCLUSIONS
Adding to published series, the presented data do not provide evidence for a relevant impact of pregnancy on recurrence behavior in OT.
Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg , Heidelberg , Germany.
Michael
M
Reich
Mira
M
Ruppenstein
Matthias D
MD
Becker
Friederike
F
Mackensen
D000293:Adolescent; D000328:Adult; D000818:Animals; D005260:Female; D005544:Forecasting; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000175:diagnosis* / Q000469:parasitology; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D014122:Toxoplasma / Q000302:isolation & purification; D014126:Toxoplasmosis, Ocular / Q000175:diagnosis* / Q000469:parasitology; D055815:Young Adult
Ocular toxoplasmosis; posterior uveitis; pregnancy; prognosis; uveitis