A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammation.
Visualization of macrophages in live animals has been of great interest for a better understanding of inflammation. We developed a near infrared (NIR) probe that can selectively detect macrophages and visualize inflammation in vivo using the IVIS spectrum, Fluorescence Molecular Tomography (FMT) and Multi-Spectral Optoacoustic Tomography (MSOT).
Singapore Bioimaging Consortium, Agency for Science, Technology and Research, 11 Biopolis Way, # 02-02 Helios, Singapore 138667, Singapore. yun_seong_wook@sbic.a-star.edu.sg.
Nam-Young
NY
Kang
Sung-Jin
SJ
Park
Xiao Wei Emmiline
XW
Ang
Animesh
A
Samanta
Wouter H P
WH
Driessen
Vasilis
V
Ntziachristos
Kristine O
KO
Vasquez
Jeffrey D
JD
Peterson
Seong-Wook
SW
Yun
Young-Tae
YT
Chang
D000818:Animals; D002478:Cells, Cultured; D003952:Diagnostic Imaging; D005456:Fluorescent Dyes; D007249:Inflammation / Q000175:diagnosis*; D008264:Macrophages / Q000473:pathology*; D051379:Mice; D019265:Spectroscopy, Near-Infrared; D014054:Tomography
D005456:Fluorescent Dyes