Doppler blood pressure measurement in pigs during anaesthesia.
To determine the accuracy of Doppler blood pressure measurement in anaesthetised pigs eight large white pigs (Sus scrofa) were anaesthetised with zolazepam and tiletamine as Zoletil 100 (4 mg/kg) and xylazine (2 mg/kg) by intramuscular injection followed by isoflurane in 100% oxygen. Blood pressure measurements were recorded using a Doppler probe on the radial artery and a catheter in the femoral artery connected to a transducer. The sample mean of the Doppler measurements were compared with the sample mean of the invasive systolic arterial blood pressure while accounting for the heart rate, end-tidal CO2 and temperature. The predicted error of the Doppler was greatest when pigs were hypotensive and normothermic: 11 mmHg (CI: 6-15). Doppler measurements should be interpreted with caution in anaesthetised pigs that are hypotensive and normothermic.
School of Veterinary and Life Sciences, Murdoch University, Australia. Electronic address: g.musk@murdoch.edu.au.
Gabrielle C
GC
Musk
School of Veterinary and Life Sciences, Murdoch University, Australia.
Renata S
RS
Costa
School of Mathematical Sciences, University of Adelaide, South Australia.
Jonathan
J
Tuke
D000758:Anesthesia / Q000662:veterinary*; D018681:Anesthetics, General / Q000008:administration & dosage*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology*; D001795:Blood Pressure Determination / Q000379:methods / Q000662:veterinary*; D001831:Body Temperature; D004338:Drug Combinations; D006339:Heart Rate / Q000502:physiology; D007273:Injections, Intramuscular; D007530:Isoflurane / Q000008:administration & dosage; D017078:Laser-Doppler Flowmetry / Q000662:veterinary*; D034421:Sus scrofa / Q000502:physiology*; D013552:Swine; D013992:Tiletamine / Q000008:administration & dosage; D014991:Xylazine / Q000008:administration & dosage; D015041:Zolazepam / Q000008:administration & dosage
D018681:Anesthetics, General; D004338:Drug Combinations; C006131:tiletamine, zolazepam drug combination; D014991:Xylazine; D013992:Tiletamine; D007530:Isoflurane; D015041:Zolazepam
Anaesthesia; Blood pressure; Pig