The First Case Report of a Systemic Allergy to OnabotulinumtoxinA (Botox) in a Healthy Patient.
To the authors' knowledge, this is the first report of an allergy to onabotulinumtoxinA. The 43-year-old woman experienced severe itching after injection of Botox and Juvéderm. Results of prick and patch testing confirmed a T-cell-mediated allergy to Botox. This case can aid in the evaluation of suspected allergies to Botox.


METHODS
5.
Dr Rosenfield is a clinical professor in the Department of Plastic Surgery, University of California-San Francisco School of Medicine, California, and an adjunct clinical professor in the Department of Plastic Surgery, Stanford University Medical School, Stanford, California office@drrosenfield.com.
Lorne King
LK
Rosenfield
Dr Kardassakis is a specialist in allergy, asthma, and immunology in private practice in San Mateo, California.
Dean George
DG
Kardassakis
Ms Tsia is an undergraduate student at the University of California, Santa Barbara, California.
Kristen Anne
KA
Tsia
Ms Stayner is an undergraduate student at Stanford University, Stanford, California.
Grace
G
Stayner
D065087:Acetylcholine Release Inhibitors / Q000008:administration & dosage* / Q000009:adverse effects; D000328:Adult; D018926:Anti-Allergic Agents / Q000627:therapeutic use; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage / Q000009:adverse effects*; D003875:Drug Eruptions / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D005260:Female; D006801:Humans; D007428:Intradermal Tests; D010328:Patch Tests; D013601:T-Lymphocytes / Q000187:drug effects* / Q000276:immunology; D016896:Treatment Outcome
D065087:Acetylcholine Release Inhibitors; D018926:Anti-Allergic Agents; D019274:Botulinum Toxins, Type A
Botox Cosmetic; contact dermatitis; hypersensitivity; onabotulinumtoxinA; systemic allergy