Patients' survival after free flap reconstructive surgery of head and neck squamous cell carcinoma: a retrospective multicentre study.
Head and neck squamous cell carcinoma of the (HNSCC) represents approximately 5% of malignant tumours in Italy. HNSCC are commonly treated with surgery or radiotherapy, or a combination of such therapies. The objectives of treatment are maximum cure rate balanced with organ preservation, restoration of form and function, reduction of morbidities and improvement or maintenance of the patient's quality of life. Immediate reconstructive surgery: local, regional or free flaps are now widely advised in the treatment of these patients. Microsurgical transfer requires expertise, is time and resource consuming, and as a whole requires substantial costs. These considerations introduce some concerns about the wide or indiscriminate use of free flap reconstructive surgery. When considering cost-benefit outcomes of such treatment, the main objective is undoubtedly, survival. This data is underreported in the current literature, whereas functional outcomes of free flaps have been largely diffused and accepted. This study collects data from 1178 patients treated with free flap reconstructive surgery following ablation of HNSCC in a group of Italian tertiary hospitals, all members of the Head & Neck Group affiliated with the Italian Society of Microsurgery. According to many authors, free flap surgery for HNSCC seems to be a beneficial option for treatment even in terms of survival.
Ospedale San Giuseppe, Milan, Italy.
P
P
Salvatori
Ospedale San Giuseppe, Milan, Italy.
S
S
Paradisi
Istituto Europeo di Oncologia, Milan, Italy.
L
L
Calabrese
Ospedale San Giuseppe, Milan, Italy.
A
A
Zani
Istituto Nazionale Tumori, Milan, Italy.
G
G
Cantù
Clinica ORL, Università di Brescia, Brescia, Italy.
J
J
Cappiello
Clinica ORL, Università di Pavia, Pavia, Italy.
M
M
Benazzo
Chirurgia Maxillo-Facciale, Università Milano - Bicocca, Milan, Italy.
A
A
Bozzetti
Azienda Ospedaliera San Camillo-Forlanini, Roma, Italy.
G
G
Bellocchi
Clinica ORL, Università di Bologna, Bologna, Italy.
A
A
Rinaldi Ceroni
Ospedale Martini, Torino, Italy.
G
G
Succo
Clinica ORL, Università di Ferrara, Ferrara, Italy.
A
A
Pastore
Istituto Europeo di Oncologia, Milan, Italy.
F
F
Chiesa
Istituto Nazionale Tumori, Milan, Italy.
S
S
Riccio
Clinica ORL, Università di Brescia, Brescia, Italy.
C
C
Piazza
Clinica ORL, Università di Pavia, Pavia, Italy.
A
A
Occhini
Chirurgia Maxillo-Facciale, Università Milano - Bicocca, Milan, Italy.
D
D
Sozzi
Azienda Ospedaliera San Camillo-Forlanini, Roma, Italy.
V
V
Damiani
Clinica ORL, Università di Bologna, Bologna, Italy.
U
U
Caliceti
Ospedale Martini, Torino, Italy.
E
E
Crosetti
Clinica ORL, Università di Ferrara, Ferrara, Italy.
S
S
Pelucchi
Ospedale Careggi, Firenze, Italy.
M
M
Squadrelli Saraceno
Ospedale San Giuseppe, Milan, Italy.
S
S
Podrecca
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000401:mortality* / Q000601:surgery*; D005260:Female; D058752:Free Tissue Flaps; D006258:Head and Neck Neoplasms / Q000401:mortality* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019651:Plastic Surgery Procedures / Q000379:methods; D012189:Retrospective Studies; D000077195:Squamous Cell Carcinoma of Head and Neck; D015996:Survival Rate; D055815:Young Adult
Free flap; Head and neck tumours; Survival