Neonatal outcome of early rescue ICSI and ICSI with ejaculated sperm.
OBJECTIVE
To evaluate the impact of early rescue ICSI on neonatal outcome.


METHODS
This retrospective study compared the neonatal outcome of early rescue ICSI and ICSI with ejaculated sperm, including 233 children who were conceived after early rescue ICSI and a control group of 906 children who were conceived after ICSI with ejaculated sperm, and all of the children had a gestational age of 20 weeks or more. The numbers of live and stillbirths, perinatal deaths, prematurity, birthweights and birth defects of the children were compared.


RESULTS
Children in the early rescue ICSI group showed no increased risk of stillbirths, perinatal death or birth defects. Those children also did not differ from those of the ICSI with ejaculated sperm group in gender rate, birthweight, gestational age or prematurity.


CONCLUSIONS
Early rescue ICSI did not increase the adverse effect on the neonatal outcome when compared to that of ICSI with ejaculated sperm.
Reproductive Medicine Center, Drum Tower Hospital Affiliated to Nanjing University Medical College, Nanjing, Jiangsu, 210008, China, chenlinjun55@163.com.
Linjun
L
Chen
Zhipeng
Z
Xu
Ningyuan
N
Zhang
Bin
B
Wang
Hua
H
Chen
Shanshan
S
Wang
Haixiang
H
Sun
D001724:Birth Weight; D004542:Ejaculation; D005260:Female; D005307:Fertilization in Vitro; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D054315:Oocyte Retrieval; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods*; D013094:Spermatozoa