Anaphylaxis secondary to chymopapain.
Anaphylaxis occurs in approximately 1% of the patients treated with chymopapain. The incidence of anaphylaxis is ten times higher in women than in men. The severity of the reaction may be attenuated by pretreatment with H1- and H2-histamine receptor antagonist. Once anaphylaxis occurs, prompt and correct treatment must be instituted.
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Whisler