Water-dispersible silicon dots as a peroxidase mimetic for the highly-sensitive colorimetric detection of glucose.
We demonstrate that photoluminescent Si-dots exhibit intrinsic peroxidase-like activity, and can catalyze the oxidization of 3,3',5,5'-tetramethylbenzidine (TMB) by H2O2, and produce a color change. This strategy can be used to detect glucose with high sensitivity and selectivity.
Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, P. R. China. zhangyy@hunnu.edu.cn.
Qiong
Q
Chen
Meiling
M
Liu
Jiangna
J
Zhao
Xue
X
Peng
Xiaojiao
X
Chen
Naxiu
N
Mi
Bangda
B
Yin
Haitao
H
Li
Youyu
Y
Zhang
Shouzhuo
S
Yao
D001560:Benzidines / Q000737:chemistry; D032701:Biomimetics; D003124:Colorimetry; D005947:Glucose / Q000032:analysis*; D007700:Kinetics; D049449:Luminescence; D008982:Molybdenum / Q000737:chemistry; D049329:Nanostructures; D010084:Oxidation-Reduction; D010544:Peroxidases / Q000737:chemistry*; D010756:Phosphoric Acids / Q000737:chemistry; D045663:Quantum Dots / Q000737:chemistry*; D012825:Silicon / Q000737:chemistry*
D001560:Benzidines; D010756:Phosphoric Acids; C020515:N,N,N',N'-tetramethylbenzidine; D008982:Molybdenum; D010544:Peroxidases; D005947:Glucose; C003125:phosphomolybdic acid; D012825:Silicon