In vitro fluorescence and phototoxicity of β-SnWO4 nanoparticles.
The nanoparticulate photocatalyst β-SnWO4 is transfected into human liver carcinoma cells (HepG2). CLSM images and MTT assays validate a high phototoxicity under artificial daylight illumination at low systemic cytotoxicity and without long-term effects. β-SnWO4 offers multifunctionality, including high colloidal stability and intrinsic fluorescence.
Karlsruhe Institute of Technology (KIT), Institut für Anorganische Chemie, Engesserstraße 15, D-76131 Karlsruhe, Germany. claus.feldmann@kit.edu.
Jan
J
Ungelenk
Carmen
C
Seidl
Eva
E
Zittel
Sabine
S
Roming
Ute
U
Schepers
Claus
C
Feldmann
D017209:Apoptosis; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D049109:Cell Proliferation; D005453:Fluorescence; D006801:Humans; D066298:In Vitro Techniques; D008027:Light; D008113:Liver Neoplasms / Q000473:pathology*; D053768:Metal Nanoparticles / Q000528:radiation effects / Q000633:toxicity*; D017971:Tin Compounds / Q000737:chemistry*; D017973:Tungsten Compounds / Q000737:chemistry*
C588367:SnWO4; D017971:Tin Compounds; D017973:Tungsten Compounds