Hydrogen sulfide is a novel gasotransmitter with pivotal role in regulating lateral root formation in plants.
Hydrogen sulfide (H2S), the third gasotransmitter after nitric oxide (NO) and carbon monoxide (CO), is a critical neuromodulator in the pathogenesis of various diseases from neurodegenerative diseases to diabetes or heart failure. The crosstalk between NO and H2S has been well established in mammalian physiology. In planta, NO is demonstrated to regulate lateral root formation by acting downstream of auxin. The recent reports revealed that H2S is a novel inducer of lateral root (LR) formation by stimulating the expression of cell cycle regulatory genes (CCRGs), acting similarly with NO, CO, and IAA. Interestingly, during the initiation of lateral root primordia, IAA is a potent inducer of endogenous H2S and CO, which is produced byL-cysteine desulfhydrase (LCD) and heme oxygenase-1 (HO-1), respectively. The increasing evidences suggest that H2S-promoted LR growth is dependent on the endogenous production of CO. In addition, our results indicate that the H2S signaling in the regulation of LR formation can be associated to NO and Ca2+. In this addendum, we advanced a proposed schematic model for H2S-mediated signaling pathway of plant LR development.
Institute of Food Quality and Safety; Jiangsu Academy of Agricultural Sciences; Nanjing, PR China.
Yan-Jun
YJ
Li
Institute of Food Quality and Safety; Jiangsu Academy of Agricultural Sciences; Nanjing, PR China.
Zhi-Qi
ZQ
Shi
College of Life Sciences; Nanjing Agricultural University; Nanjing, PR China.
Li-Jun
LJ
Gan
Institute of Food Quality and Safety; Jiangsu Academy of Agricultural Sciences; Nanjing, PR China.
Jian
J
Chen
auxin; calcium; carbon monoxide; gasotransmitter; hydrogen sulfide; lateral root; signal molecule