No Intense 18F-Fluorodeoxyglucose Uptake in Positron Emission Tomography of a Metastatic Orbital Tumor From Breast Carcinoma.
A 47-year-old woman with a history of invasive ductal carcinoma in the right breast reported decreased vision in the OD for the past 3 months. Her best corrected visual acuity was 0.1 OD and 1.0 OS. T1-weighted MRI revealed enlargement of the right lateral rectus muscle with a faint tumor outline and no contrast enhancement in the lesion. F-fluorodeoxyglucose positron emission tomography did not demonstrate intense uptake at the lesion. Because the patient demonstrated optic neuropathy due to compression by the enlarged muscle, balanced orbital decompression (of the deep lateral and medial orbital walls) was performed simultaneously with a tumor biopsy. Visual acuity of the OD was dramatically improved to 1.0. The histopathological examination demonstrated similar findings to her breast carcinoma. F-fluorodeoxyglucose positron emission tomography does not always show a positive result for an orbital tumor that has metastasized from the breast.
*Department of Ophthalmology, Aichi Medical University, Nagakute, Aichi; †Department of Radiology, Wakayama Medical University, Wakayama; and ‡Department of Pathology, Aichi Medical University Hospital, Nagakute, Aichi, Japan.
Hiromichi
H
Matsuda
Yasuhiro
Y
Takahashi
Kouhei
K
Nakata
Atsuko
A
Kitamura
Hirohiko
H
Kakizaki
D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging* / Q000556:secondary; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism*; D006801:Humans; D008279:Magnetic Resonance Imaging; D015409:Mastectomy, Radical; D008525:Medroxyprogesterone / Q000627:therapeutic use; D008875:Middle Aged; D019042:Muscle Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D009801:Oculomotor Muscles / Q000000981:diagnostic imaging; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D017239:Paclitaxel / Q000627:therapeutic use; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals / Q000378:metabolism*; D014786:Vision Disorders / Q000175:diagnosis
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D008525:Medroxyprogesterone; D017239:Paclitaxel