Risk and benefit assessment of potential neurodevelopmental effect resulting from consumption of marine fish from a coastal archipelago in China.
The aim of this study was to assess net neurodevelopmental effect via maternal consumption of marine fish. A total of thirty-one species were collected from Zhoushan, China. The net IQ point gain was assessed by FAO/WHO deterministic approach and probabilistic computation (if necessary). Results of the deterministic assessment of two samples belonging to Scoliodon sorrakowah showed negative IQ point gain in both common and extreme consumption scenarios (175 and 450 g/week, respectively); the net IQ gain caused by both consumption scenarios of other species were positive. Both consumption scenarios of Scoliodon sorrakowah showed beneficial neurodevelopmental effect according to probabilistic computation (95% CI for mean of net IQ gain: 0.0536-0.0554 and 0.1377-0.1425, respectively). Except for Scoliodon sorrakowah, this study indicates that both consumption scenarios of other studied species would be recommended according to the FAO/WHO approach. There would be no recommendation of consumption scenarios of Scoliodon sorrakowah for the reason for carefulness.
China National Center for Food Safety Risk Assessment, Key Lab of Food Safety Risk Assessment, Ministry of Health , No. 7, Panjiayuan Nanli, Peking 100021, China.
Yi-Xiong
YX
Gao
Hongxia
H
Zhang
Xinwei
X
Yu
Jia-lu
JL
He
Xiaohong
X
Shang
Xiaowei
X
Li
Yunfeng
Y
Zhao
Yongning
Y
Wu
D000818:Animals; D002681:China; D004281:Docosahexaenoic Acids / Q000378:metabolism; D005399:Fishes / Q000145:classification / Q000378:metabolism*; D005506:Food Contamination / Q000032:analysis*; D006801:Humans; D008767:Methylmercury Compounds / Q000378:metabolism / Q000633:toxicity*; D009420:Nervous System / Q000187:drug effects / Q000254:growth & development* / Q000378:metabolism; D018570:Risk Assessment; D017747:Seafood / Q000009:adverse effects* / Q000032:analysis
D008767:Methylmercury Compounds; D004281:Docosahexaenoic Acids