Palladium-catalyzed α-ketocyclopropanation of norbornenes with propargyl acetates.
Propargyl acetates reacted with norbornene in the presence of a catalytic amount of tetrakis(tripheylphosphine)palladium to give cyclopropyl ketones. The reaction proceeded with high stereoselectivity, affording a single stereoisomer. The reaction of various substituted norbornenes gave the corresponding cyclopropanes in moderate to good yields.
Department of Chemistry, Graduate School of Science and ‡Research Institute of Green Science and Technology, Shizuoka University , Shizuoka 422-8529, Japan.
Yuta
Y
Tanioka
Naofumi
N
Tsukada