Matrix effect in ligand-binding assay: the importance of evaluating emerging technologies.
Janssen R&D, L.L.C., 200 Great Valley Parkway, Malvern, PA, USA. rcrisino@its.jnj.com.
Rebecca M
RM
Crisino
Linlin
L
Luo
Brian
B
Geist
Jad
J
Zoghbi
Franklin
F
Spriggs
D000906:Antibodies / Q000032:analysis; D006801:Humans; D007118:Immunoassay / Q000295:instrumentation / Q000379:methods* / Q000592:standards; D062069:Inventions; D004364:Pharmaceutical Preparations / Q000032:analysis
D000906:Antibodies; D004364:Pharmaceutical Preparations
emerging technology; immunogenicity; innovation; ligand-binding assay; matrix effect; matrix interference; pharmacokinetic; technology evaluation