Postinfectious bronchiolitis obliterans in children: the South American contribution.
Postinfectious bronchiolitis obliterans (PIBO) is an infrequent chronic lung that causes irreversible obstruction and, or, obliteration of the smaller airways. This review particularly focuses on more than 30 studies from South America.


CONCLUSIONS
The initial PIBO event occurs in the early years of life and is strongly associated with adenovirus infection and the need for mechanical ventilator support. Treatment requires a multidisciplinary strategy. Multicentre studies are needed to determine progression, optimal management and long-term follow-up.
Pulmonology Unit, Departments of Pediatrics, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Jose A
JA
Castro-Rodriguez
Veronica
V
Giubergia
Gilberto B
GB
Fischer
Claudio
C
Castaños
Edgar E
EE
Sarria
Ramiro
R
Gonzalez
Rita
R
Mattiello
Luis E
LE
Vega-Briceño
Patricia
P
Murtagh
D001989:Bronchiolitis Obliterans / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology* / Q000628:therapy; D006801:Humans; D012129:Respiratory Function Tests; D012307:Risk Factors; D013020:South America
Adenovirus; Bronchiolitis obliterans; Children; Chronic lung disease; South America