New intracellular and molecular aspects in pathophysiology of colorectal cancer.
Colorectal cancer is one of the most common malignancy in the world and the second cancer-related death, many molecular and genetic aspects of this disease have been cleared as chromosomal instability and the role of some key proteins as WNT/β catenin, trypsin and others. Also recently the role of folate turnover and some neurotransmitters as serotonin were also considered. The scope of this review is to describe some details about new molecular pathways suggested for occurrence or progress of this disease.
Cell and Molecular Research Lab, Amol Research Center, Pasteur Institute of Iran, Amol, Iran ; Parasitiology Department, Amol Research Center, Pasteur Institute of Iran, Amol, Iran.
Payman
P
Ziapour
Cell and Molecular Research Lab, Amol Research Center, Pasteur Institute of Iran, Amol, Iran.
Ramin
R
Ataee
Parasitiology Department, Amol Research Center, Pasteur Institute of Iran, Amol, Iran.
Mohammad
M
Shadifar
Biochemistry Department, Armand Frappier Institute, Monntreal, Canada.
Cathy
C
Vaillancourt
Biochemistry Lab, Amol Research Center, Pasteur Instute of Iran, Amol, Iran.
Ali
A
Ahmadi
Pharmacology Department, Faculty Of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Majid
M
Jafari-Sabet
Pharmacology Department, Babol Medical Univesity, Babol, Iran.
Amin
A
Ataee
Colorectal cancer; Molecular pathology; Serotonin; Trypsin; WNT protein