Hydrotrifluoromethylthiolation of α-diazo esters--synthesis of α-SCF3 substituted esters.
A practical protocol for hydrotrifluoromethylthiolation of diazo compounds has been developed. A range of diazo compounds in combination with a nucleophilic SCF3 source provided access to valuable trifluoromethylthiolated compounds. Furthermore, a methodology for the first double trifluoromethylthiolation was developed.
Institute of Organic Chemistry, RWTH Aachen, Landoltweg1, 52074 Aachen, Germany. Magnus.Rueping@rwth-aachen.de.
Quentin
Q
Lefebvre
Eleonora
E
Fava
Pavlo
P
Nikolaienko
Magnus
M
Rueping