[Acute blindness secondary to quinine toxicity: role of hyperbaric oxygen treatment].
We report a rare case of quinine toxicity causing acute bilateral blindness, followed by documented partial recovery within 24 hours. The patient was treated with hyperbaric oxygenotherapy and intravenous nitrates. Visual defects persist after 6 months.
Service d'ophtalmologie, hôpital du Val-de-Grâce, 74, boulevard de Port-Royal, 75005 Paris, France. Electronic address: afmarill@gmail.com.
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Marill
Service d'ophtalmologie, hôpital Pellegrin, CHU de Bordeaux, place Amélie-Raba-Léon, 33000 Bordeaux, France; Université Bordeaux Segalen, 146, rue Léo-Saignat, 33076 Bordeaux, France; Inserm, ISPED, centre Inserm U897, épidémiologie-biostatistique, 146, rue Léo-Saignat, 33076 Bordeaux, France.
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Delyfer
Service d'ophtalmologie, hôpital du Val-de-Grâce, 74, boulevard de Port-Royal, 75005 Paris, France.
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JP
Renard
Service d'ophtalmologie, hôpital Pellegrin, CHU de Bordeaux, place Amélie-Raba-Léon, 33000 Bordeaux, France; Université Bordeaux Segalen, 146, rue Léo-Saignat, 33076 Bordeaux, France; Inserm, ISPED, centre Inserm U897, épidémiologie-biostatistique, 146, rue Léo-Saignat, 33076 Bordeaux, France.
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JF
Korobelnik
D000208:Acute Disease; D000328:Adult; D000962:Antimalarials / Q000009:adverse effects*; D001766:Blindness / Q000139:chemically induced* / Q000628:therapy*; D005260:Female; D006801:Humans; D006931:Hyperbaric Oxygenation; D009553:Nimodipine / Q000627:therapeutic use; D011803:Quinine / Q000009:adverse effects*; D014665:Vasodilator Agents / Q000627:therapeutic use
D000962:Antimalarials; D014665:Vasodilator Agents; D009553:Nimodipine; D011803:Quinine
Amaurose; Amaurosis; Hyperbaric oxygenotherapy; Intoxication aiguë à la quinine; Oxygénothérapie hyperbare; Quinine toxicity; Vasodilatateur; Vasodilator