Multinucleate cell angiohistiocytoma: a case report and review of the literature.
Multinucleate cell angiohistiocytoma (MCAH) is a rare, benign vascular proliferation. Fewer than 80 cases have been reported to date, which may relate to under-recognition of this entity. Lesions are commonly asymptomatic and appear as erythematous to violaceous papules on the lower extremities and dorsal hands of middle-aged to elderly women. The characteristic histopathologic and immunohistochemical features of MCAH are essential for definitive diagnosis of MCAH. Multinucleate cell angiohistiocytoma follows a slowly progressive course, although spontaneous regression has been reported in rare cases. We present a case of MCAH to increase awareness and elucidate the characteristic clinical and histopathologic features of this disorder.
Danielle S
DS
Applebaum
Fareesa
F
Shuja
Lindsey
L
Hicks
Clay
C
Cockerell
Baylor College of Medicine.
Sylvia
S
Hsu
D000368:Aged; D002467:Cell Nucleus / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology*; D006801:Humans; D007866:Leg / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*