[Study of ADC value in healthy adults kidney of different age groups].
OBJECTIVE
To evaluate the changes of ADC value on renal parenchyma at different age groups in healthy adults.


METHODS
One hundred healthy adults were divided into five groups based on age:namely 18-29 years, 30-39 years, 40-49 years, 50-59 years and 60-69 years. All adults underwent diffusion-weighted magnetic resonance(MR) imaging of the kidneys with b values of 800 s/mm(2). ADC values of renal parenchyma were measured by the manufacturer's software.


RESULTS
With the increasing of age , the renal parenchyma ADCs decrease. The ADCs of renal parenchyma in five age groups were (2.07 ± 0.10) ×10(-3)mm(2)/s, (2.06 ± 0.12) ×10(-3)mm(2)/s, (2.03 ± 0.10) ×10(-3)mm(2)/s, (1.98 ± 0.17) ×10(-3)mm(2)/s and (1.94 ± 0.12) ×10(-3)mm(2)/s, which had statistically significant different (F = 3.375, P < 0.05).


CONCLUSIONS
(1)The ADCs of renal parenchyma may be influenced by age , with the increasing of age, ADCs of normal kidney presented tenuous decreasing tendency especially the people aged ≥ 40 years; (2)in clinical application, we ought to pay attention to the influence of age factor. Income data of this study can be took as normal reference value in other more study.
Department of Radiology,General Hospital of Chinese People's Liberation Army,Beijing 100853, China.
Yehuan
Y
Tang
Jingjing
J
Pan
Haiyi
H
Wang
Xinkun
X
Wang
Lu
L
Li
Email: yehuiyi301@aliyun.com.
Huiyi
H
Ye
D000293:Adolescent; D000328:Adult; D000368:Aged; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D007668:Kidney / Q000033:anatomy & histology*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D055815:Young Adult