Time-to-peak values can estimate hepatic functional reserve in patients undergoing surgical resection: a comparison between perfusion CT and indocyanine green retention test.
OBJECTIVE
To evaluate the potential usefulness of perfusion computed tomography (CT) for the estimation of hepatic functional reserve in patients scheduled for surgical resection and to compare the results with those of the indocyanine green retention test results.


METHODS
Thirty-one patients with hepatobiliary malignancies were included. Perfusion CT and indocyanine green retention test were performed on the same day, and their results were compared using Pearson correlation test.


RESULTS
A strong correlation was found between perfusion CT time-to-peak values and indocyanine green retention rate at 15 minutes and indocyanine green plasma disappearance rate values (R, 0.789 and -0.790; R, 0.832 and -0.823, respectively; P < 0.0001).


CONCLUSIONS
Perfusion CT may be useful for the preoperative noninvasive estimation of hepatic functional reserve for patients undergoing liver resection.
From the *Departments of Radiology and †Surgery, G.B. Rossi Hospital, University of Verona, Verona, Italy; and ‡Department of Prevention, Provincial Health Services Agency, Trento, Italy; Department of Public Health and Community Medicine, University of Verona, Italy.
Mirko
M
D'Onofrio
Riccardo
R
De Robertis
Andrea
A
Ruzzenente
William
W
Mantovani
Gino
G
Puntel
Stefano
S
Crosara
Stefano
S
Canestrini
Alfredo
A
Guglielmi
Roberto Pozzi
RP
Mucelli
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006498:Hepatectomy; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D007208:Indocyanine Green / Q000032:analysis*; D008111:Liver Function Tests / Q000379:methods*; D008113:Liver Neoplasms / Q000097:blood* / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D055420:Perfusion Imaging / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*
D007208:Indocyanine Green