Oncologic outcomes of supratracheal laryngectomy: Critical analysis.
BACKGROUND
Laryngeal cancer management should pursue function-sparing therapeutic options. Even though demolitive surgery provides better control of disease at intermediate to advanced stages when compared to chemoradiotherapy, it does not preserve laryngeal function. Supratracheal partial laryngectomy has been described as a function-sparing surgical technique for laryngeal cancer with subglottic extension.


METHODS
In this retrospective study, we analyzed the clinical outcomes of 115 patients who underwent supratracheal partial laryngectomy.


RESULTS
At 5 years, overall survival (OS), disease-free survival (DFS), and locoregional control rates were 78.9%, 68.5%, and 69.6%, respectively; DFS and locoregional control prevalences were greatly affected by pT4a classification (49.0% and 51.4%, respectively); and laryngeal function preservation was maintained in 78.3% of patients despite being affected by pT4a classification (59.3%) and age ≥65 (64.6%).


CONCLUSIONS
For cases with glottic tumors and with subglottic extension, the choice of supratracheal partial laryngectomy versus chemoradiotherapy can be considered to be effective in terms of prognostic and functional results.
Otorhinolaryngology Department, Vittorio Veneto Hospital, Vittorio Veneto, Treviso, Italy.
Giuseppe
G
Rizzotto
Otorhinolaryngology Department, Martini Hospital, Turin, Italy.
Erika
E
Crosetti
Otorhinolaryngology Department, Vittorio Veneto Hospital, Vittorio Veneto, Treviso, Italy.
Marco
M
Lucioni
Otorhinolaryngology Department, Vittorio Veneto Hospital, Vittorio Veneto, Treviso, Italy.
Andy
A
Bertolin
Otorhinolaryngology Department, San Luigi Gonzaga Hospital, Turin, Italy.
Valentina
V
Monticone
Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.
Andrea Elio
AE
Sprio
Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.
Giovanni Nicolao
GN
Berta
Otorhinolaryngology Department, San Luigi Gonzaga Hospital, Turin, Italy.|Department of Oncology, University of Turin, Turin, Italy.
Giovanni
G
Succo
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy / Q000009:adverse effects / Q000379:methods*; D007830:Larynx / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome; D055815:Young Adult
aspiration pneumonia; laryngeal cancer; laryngeal function sparing protocol; open partial laryngectomy; supratracheal partial laryngectomy