Successful increase in uterine volume and subsequent pregnancy in a patient with a history of radiation and chemotherapy.
A 26-year-old woman with a history of cranial radiation and chemotherapy desired pregnancy. Pelvic ultrasound scanning demonstrated a small uterine volume of 7 mL. After 25 weeks of estrogen therapy, her uterine volume increased to 37 mL. The patient had an uncomplicated pregnancy with the use of donor oocytes and delivered a term healthy daughter.
Department of Obstetrics, Gynecology and Women's Health, University of Louisville, Louisville, KY. Electronic address: ms.krause@yahoo.de.
Miriam S
MS
Krause
Department of Obstetrics, Gynecology and Women's Health, University of Louisville, Louisville, KY.
M Symmes
MS
Johnson
Department of Obstetrics, Gynecology and Women's Health, University of Louisville, Louisville, KY.
Abigail A
AA
Delaney
Department of Obstetrics, Gynecology and Women's Health, University of Louisville, Louisville, KY.
Henry
H
Bohler
Department of Obstetrics, Gynecology and Women's Health, University of Louisville, Louisville, KY.
Steven T
ST
Nakajima
D000282:Administration, Intravaginal; D000284:Administration, Oral; D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects; D001755:Blastocyst; D002528:Cerebellar Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D004624:Embryo Transfer; D004958:Estradiol / Q000008:administration & dosage*; D004967:Estrogens / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy; D050498:Live Birth; D008527:Medulloblastoma / Q000188:drug therapy / Q000532:radiotherapy; D018587:Oocyte Donation; D011247:Pregnancy; D016649:Primary Ovarian Insufficiency / Q000150:complications / Q000209:etiology; D014463:Ultrasonography; D014599:Uterus / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000254:growth & development*
D000970:Antineoplastic Agents; D004967:Estrogens; D004958:Estradiol
estradiol treatment; pregnancy; radiation; uterine volume