Evaluation of plasma eosinophil count and mean platelet volume in patients with coronary slow flow.
OBJECTIVE
The pathophysiology of coronary slow flow has not been clearly defined, although multiple abnormalities including arteritis, endothelial dysfunction, and atherothrombosis, have been reported. It is known that eosinophils play an important role in inflammation, endothelial dysfunction, and thrombosis. We aimed to compare the eosinophil counts of coronary slow flow patients versus healthy controls.


METHODS
This study included 50 coronary slow flow patients (19 males, mean age 65.6 ± 13.7 years) and 30 healthy controls (10 males, mean age 57.86 ± 11.6 years). These participants were evaluated using concurrent routine biochemical tests as well as neutrophil, lymphocyte, and eosinophil counts and mean platelet volume (MPV), which were obtained from the whole blood count. These parameters were compared between groups.


RESULTS
The baseline characteristics of the study groups were comparable. The coronary slow flow patients had a higher mean platelet volume and eosinophil count than the control group (8.38 ± 0.86 vs 6.28 ± 1.6 fL and 0.31 ± 0.42 vs 0.09 ± 0.05; p<0.001 and 0.008, respectively).


CONCLUSIONS
Our study demonstrated a relationship between eosinophil count and MPV in patients with coronary slow flow.
Cardiology Department, Bursa Yüksek ?htisas Education and Research Hospital, Bursa, Turkey.
Mehmet
M
Demir
Cardiology Department, Bursa Yüksek ?htisas Education and Research Hospital, Bursa, Turkey.
Selvi
S
Coşar
Cardiology Department, Bursa Yüksek ?htisas Education and Research Hospital, Bursa, Turkey.
Mehmet
M
Melek
D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity / Q000502:physiology; D017023:Coronary Angiography / Q000379:methods; D003324:Coronary Artery Disease / Q000097:blood* / Q000000981:diagnostic imaging; D003326:Coronary Circulation; D004804:Eosinophils; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D063847:Mean Platelet Volume / Q000379:methods*; D008875:Middle Aged; D010976:Platelet Count