Automatic Alignment of Myocardial Perfusion Images With Contrast-Enhanced Cardiac Computed Tomography.
Explicit fusion of perfusion data from Positron Emission Tomography (PET) or Single Photon Emission Computed Tomography (SPECT) with coronary artery anatomy from Computed Tomographic Coronary Angiography (CTA) has been shown to improve the diagnostic yield for coronary artery disease (CAD) compared to either modality alone. However, most clinically available methods were developed for multimodal scanners or require interactive alignment prior to display and analysis. A new approach was developed to register the two distributions obtained either from a single multimodal imager or from separate scanners, and a preliminary validation was undertaken to compare the automatic alignment to interactive alignment by two experts.
Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA 30322 USA.
Tracy L
TL
Faber
Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA 30322 USA.
Cesar A
CA
Santana
Department of Mathematics and Computer Science, Emory University, Atlanta, GA 30322 USA.
Marina
M
Piccinelli
Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA 30322 USA.
Jonathon A
JA
Nye
Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA 30322 USA.
John R
JR
Votaw
Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA 30322 USA.
Ernest V
EV
Garcia
Emory University, Atlanta, GA 30322 USA. He is now with the Department of Mathematics, University of British Columbia, Vancouver, BC V6T IZ2, Canada.
Eldad
E
Haber
Computer-aided diagnosis; image registration; nuclear medicine