Bladder cancer: bladder preservation--learning what we don't know.
Bladder preservation for patients with muscle-invasive bladder cancer has the potential to offer a quality-of-life advantage, but owing to the lack of randomized trials oncological equivalence to surgery has not been demonstrated. A new article provides a comprehensive overview of the current status of this procedure, but raises timely and important questions.
University of Michigan Comprehensive Cancer Center, 1500 East Medical Center Drive, 7314 CC, Ann Arbor, MI 48109, USA.
Maha
M
Hussain
University of Colorado Comprehensive Cancer Center, 13001 East 17th Place, MS #F-434, Aurora, CO 80045, USA.
Dan
D
Theodorescu
D015653:Cystectomy / Q000379:methods; D006801:Humans; D019042:Muscle Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D009361:Neoplasm Invasiveness; D059351:Organ Sparing Treatments; D018579:Patient Selection; D011788:Quality of Life; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*