Isolated Zygomycetes Endophthalmitis: A Case Report.
Mucormycosis is a rare fungal infection typically limited to immunocompromised patients or patients with diabetes., Clinical manifestation varies, with rhino-orbital-cerebral mucormycosis as the most common presentation. The authors present here a 56-year-old man who complained of isolated OD pain with no evidence of cerebral or sinus inflammation on imaging. Enucleation was eventually performed, and histopathology of the globe demonstrated characteristics of zygomycetes infection. Intraocular mucormycosis is rare and when reported is related to contiguous spread of disease or surgical inoculation. After thorough literature review, the authors believe this to be the first reported case of isolated intraocular mucormycosis in a patient with no prior history of ocular surgery.
*Department of Opthalmology, Columbia University, College of Physicians and Surgeons, New York, New York; and †Department of Opthalmology, Jules Stein Eye Institute, University of California, Los Angeles, California, U.S.A.
Juliet
J
Idiga
Daniel B
DB
Rootman
Aaron
A
Nagiel
Robert A
RA
Goldberg
D001706:Biopsy; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D009877:Endophthalmitis / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000601:surgery; D015353:Eye Enucleation; D015821:Eye Infections, Fungal / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009090:Mucorales / Q000302:isolation & purification*; D009091:Mucormycosis / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000601:surgery; D014057:Tomography, X-Ray Computed