Zoaramine, a zoanthamine-like alkaloid with a new skeleton.
Chemical investigation of an Atlantic variety of Zoanthus sp. led to the isolation of two new metabolites, zoaramine and zoarenone. Their structures were deduced by the use of NMR spectroscopy and computational calculation of (1)H and (13)C chemical shifts. The core of these novel compounds resembles the structure of norzoanthamine alkaloids, and their isolation represents an important step toward a better understanding of the biogenetic origin of this group of antiosteoporotic molecules.
University Institute of Bio-Organic Chemistry "Antonio González" and §Department de Chemical Engeneering and Pharmaceutical Technology, University of La Laguna , 38206 Tenerife, Spain.
Francisco
F
Cen-Pacheco
Manuel
M
Norte
José J
JJ
Fernández
Antonio Hernández
AH
Daranas
D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry*; D001381:Azepines / Q000138:chemical synthesis* / Q000737:chemistry; D002247:Carbon Isotopes / Q000737:chemistry*; D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis* / Q000737:chemistry; D006859:Hydrogen / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry
D000470:Alkaloids; D001381:Azepines; D002247:Carbon Isotopes; D006576:Heterocyclic Compounds, 4 or More Rings; D011804:Quinolines; C542309:zoanthamine; D006859:Hydrogen