Stroke type differentiation using spectrally constrained multifrequency EIT: evaluation of feasibility in a realistic head model.
We investigate the application of multifrequency electrical impedance tomography (MFEIT) to imaging the brain in stroke patients. The use of MFEIT could enable early diagnosis and thrombolysis of ischaemic stroke, and therefore improve the outcome of treatment. Recent advances in the imaging methodology suggest that the use of spectral constraints could allow for the reconstruction of a one-shot image. We performed a simulation study to investigate the feasibility of imaging stroke in a head model with realistic conductivities. We introduced increasing levels of modelling errors to test the robustness of the method to the most common sources of artefact. We considered the case of errors in the electrode placement, spectral constraints, and contact impedance. The results indicate that errors in the position and shape of the electrodes can affect image quality, although our imaging method was successful in identifying tissues with sufficiently distinct spectra.
University College London, London WC1E 6BT, UK.
Emma
E
Malone
Markus
M
Jehl
Simon
S
Arridge
Timo
T
Betcke
David
D
Holder
D017097:Electric Impedance; D004566:Electrodes; D005240:Feasibility Studies; D006257:Head; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008959:Models, Neurological; D009716:Numerical Analysis, Computer-Assisted; D015203:Reproducibility of Results; D020521:Stroke / Q000175:diagnosis*; D014054:Tomography / Q000379:methods*