Successful bilateral lung transplantation after 16 h of lung preservation with EP-TU solution: report of a case.
We report a case of bilateral lung transplantation (BLT) after preservation of the donor graft for 16 h 5 min with EP-TU, an extracellular phosphate-buffered lung preservation solution. The recipient was a 26-year-old woman with idiopathic pulmonary arterial hypertension and the graft ischemic time was prolonged significantly because of the time required to induce peripheral veno-arterial extracorporeal membrane oxygenation (V-A ECMO) under local anesthesia, and address the severe intrathoracic and pericardial adhesions from past surgery for partial anomalous pulmonary venous return, with concurrent annular plication of the tricuspid valve. After the operation, ECMO and continuous hemodiafiltration were started preemptively to protect the grafts against excessive edema. Postoperative chest X-ray showed diffuse bilateral infiltrates, which improved within a few days and she was weaned off ECMO on day 9. Successful BLT after a graft ischemic time of over 16 h has rarely been described in clinical lung transplantation.
Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryo-machi Aoba-ku, Sendai, 980-8575, Japan.
Hisashi
H
Oishi
Yoshinori
Y
Okada
Yoshikatsu
Y
Saiki
Tetsu
T
Sado
Masafumi
M
Noda
Yasushi
Y
Hoshikawa
Chiaki
C
Endo
Akira
A
Sakurada
Sumiko
S
Maeda
Miki
M
Akiba
Kunihiko
K
Hoshi
Takashi
T
Kondo
D000328:Adult; D065627:Familial Primary Pulmonary Hypertension / Q000601:surgery*; D005260:Female; D006801:Humans; D016040:Lung Transplantation / Q000379:methods*; D008297:Male; D009926:Organ Preservation / Q000379:methods*; D019188:Organ Preservation Solutions; D010710:Phosphates; D055031:Primary Graft Dysfunction / Q000517:prevention & control; D013997:Time Factors; D014019:Tissue Donors; D016896:Treatment Outcome; D055815:Young Adult
D019188:Organ Preservation Solutions; D010710:Phosphates