Self-expanding prostheses for transcatheter aortic valve replacement.
Transcatheter aortic valve replacement (TAVR) has emerged as an alternative to surgical aortic valve replacement in patients who are considered high surgical risk or inoperable due to advanced age and comorbidities. Randomized trial and registry data have demonstrated the safety and efficacy of TAVR in such patients. Currently available transcatheter heart valves (THVs) employ either balloon-expandable or self-expanding designs, and several new designs have shown promising early results. Differences in valve design may offer specific advantages for accurate deployment and minimizing complications. This article reviews several designs of self-expanding THVs that are currently available or have undergone successful implantation in humans. Additional studies are required to compare the relative performance of these devices.
Division of Cardiology, Sharp Rees-Stealy Medical Group, San Diego, CA.
Robert
R
Kumar
Interventional Cardiology Unit, San Raffaele Scientific Institute, Milan, Italy.
Azeem
A
Latib
Interventional Cardiology Unit, San Raffaele Scientific Institute, Milan, Italy.
Antonio
A
Colombo
Department of Structural and Congenital Heart Disease, Lenox Hill Heart and Vascular Institute, North Shore/LIJ Health System, New York, NY. Electronic address: cruiz@nshs.edu.
Carlos E
CE
Ruiz
D001021:Aortic Valve / Q000503:physiopathology; D001024:Aortic Valve Stenosis / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D006328:Cardiac Catheterization / Q000009:adverse effects / Q000295:instrumentation*; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D018579:Patient Selection; D011474:Prosthesis Design; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome
Aortic stenosis; Aortic valve; Percutaneous; Self-expanding; Transcatheter