Characteristics of Alzheimer's disease among patients in Taiwan, Hong Kong, and Beijing.
In order to obtain data from patients with Alzheimer's disease dementia and their informants in a uniform manner and to foster further research among the Chinese and other races, we have conducted an international study to recruit patients diagnosed with Alzheimer's disease (AD) from Taiwan, Hong Kong, and Beijing. The Uniform Data Set was translated into Chinese and administrated to AD patients and their informants. A total of 1,107 AD dementia patients were recruited, including 691 from Taiwan, 244 from Beijing, and 172 from Hong Kong. There were differences in the AD patients: gender (p = 0.099), education (p < 0.001), age (p < 0.001), and handedness (p = 0.007). For informants, age (p = 0.679), gender (p = 0.117), education (p < 0.001), and living together or not (p < 0.001) differed in the three samples. Although three areas across the Taiwan Strait are ethnic Chinese, the clinical picture for patients and informants are very different. Further study is needed to clarify the significance of clinical characteristics in Chinese societies.
Department of Neurology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan Department of and Master's Program in Neurology, Faculty of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan Mentality Protection Center, Fo Guang Shan Compassion Foundation, Taiwan.
Yuan-Han
YH
Yang
Dementia Care and Research Center, Peking University Institute of Mental Health, Beijing, China.
Huali
H
Wang
Department of Psychiatry, Chinese University of Hong Kong, Hong Kong, China.
Linda
L
Lam
Department of Psychiatry, University of Hong Kong, Hong Kong.
Wai-Chi
WC
Chan
Dementia Care and Research Center, Peking University Institute of Mental Health, Beijing, China.
Xin
X
Yu
Dementia Care and Research Center, Peking University Institute of Mental Health, Beijing, China.
Tao
T
Li
Department of Neurology, Changhua Christian Hospital,Changhua, Taiwan Center for General Education, Central Taiwan University of Science and Technology, Taichung, Taiwan.
Wen-Fu
WF
Wang
Department of Neurology, Lin Shin Hospital, Taichung, Taiwan.
Pai-Yi
PY
Chiu
Section of Neurology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Yu-Te
YT
Lin
Department of Neurology, Shung Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Chaur-Jong
CJ
Hu
Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan.
Jong-Ling
JL
Fuh
Charles F. and Joanne Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.
John C
JC
Morris
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000208:ethnology* / Q000503:physiopathology*; D044466:Asian People; D017028:Caregivers / Q000706:statistics & numerical data; D002681:China; D004522:Educational Status; D005260:Female; D007839:Functional Laterality; D006723:Hong Kong; D006798:Housing; D006801:Humans; D008297:Male; D017533:Marital Status; D012737:Sex Factors; D013624:Taiwan
Alzheimer's disease; Beijing; Hong Kong; Taiwan; informant; uniform data set