Amphiphilic nanocapsules entangled with organometallic coordination polymers for controlled cargo release.
A class of new amphiphilic nanocapsules entangled with organometallic coordination polymers has been developed for the first time. Poly(2-(N,N-dimethyl amino)ethyl methacrylate)-b-polystyrene capped with β-cyclodextrin (β-CD) (CD-PDMAEMA-b-PS) is first synthesized using sequent RAFT polymerization of styrene and 2-(N,N-dimethyl amino)ethyl methacrylate with xanthate modified β-CD as chain transfer agent. The end group of β-CD is allowed to include 4,4'-bipyridine through host-guest inclusion to yield PDMAEMA-b-PS terminated with an inclusion complex of β-CD and bipyridine (bpy-PDMAEMA-b-PS), which is then used as surfactant to prepare emulsion droplets in toluene/water mixture. Upon addition of Ni(II), bipyridine coordinates with Ni(II) to form coordination polymers in the periphery of emulsion droplets, affording amphiphilic capsules entangled with organometallic coordination polymers, as confirmed by GPC, (1)H NMR, SEM, TEM, DLS, and so on. The organometallic coordination polymer capsules are capable of encapsulating organic cargoes. Interestingly, encapsulated cargoes can be extracted from the capsules without damaging the capsules. Such capsules are potential candidates for encapsulating and controlled release of organic cargoes.
DSAP Lab, PCFM Lab, School of Chemistry and Chemical Engineering, Sun Yat-Sen University , Guangzhou 510275, China.
Guodong
G
Liang
Huan
H
Ni
Suping
S
Bao
Fangming
F
Zhu
Haiyang
H
Gao
Qing
Q
Wu
Ben Zhong
BZ
Tang
D016503:Drug Delivery Systems; D009682:Magnetic Resonance Spectroscopy; D008689:Methacrylates / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D008970:Molecular Weight; D053769:Nanocapsules / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D009532:Nickel / Q000737:chemistry; D009757:Nylons / Q000737:chemistry*; D009930:Organic Chemicals / Q000737:chemistry; D010078:Oxazines / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D011137:Polystyrenes / Q000737:chemistry; D011725:Pyridines / Q000737:chemistry; D013501:Surface-Active Agents; D047392:beta-Cyclodextrins / Q000737:chemistry
D008689:Methacrylates; D053769:Nanocapsules; D009757:Nylons; D009930:Organic Chemicals; D010078:Oxazines; D011108:Polymers; D011137:Polystyrenes; D011725:Pyridines; D013501:Surface-Active Agents; D047392:beta-Cyclodextrins; C407037:poly(2-(dimethylamino)ethyl methacrylate); D009532:Nickel; C031215:betadex; C044808:nile red