Optimization of β-cyclodextrin cross-linked polymer for monitoring of quercetin.
A novel method for the separation/analysis of quercetin was described, which was based on the investigation of the inclusion interactions of β-cyclodextrin cross-linked polymer (β-CDCP) with quercetin (Qu) and the adsorption behavior of Qu on β-CDCP. The inclusion interaction of β-CDCP with Qu was studied through FTIR, TGA and 13C NMR. Under the optimum conditions, the preconcentration factor of the proposed method was approximately 8.8, the β-CDCP could be used repeatedly for 30 times and offered better recovery. The linear range, limit of detection (LOD) and the relative standard deviation (RSD) was found to be 0.10-12.0 μg mL(-1), 4.6 ng mL(-1) and 3.10% (n=3, c=2.0 μg mL(-1)) respectively. This technique had been successfully applied to the determination of Qu in real samples.
College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225009, China. Electronic address: xszhu@yzu.edu.cn.
Xiashi
X
Zhu
College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225009, China.
Wenhui
W
Ping
D000327:Adsorption; D000818:Animals; D002482:Cellulose / Q000737:chemistry*; D003432:Cross-Linking Reagents / Q000737:chemistry*; D003505:Cyclodextrins / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007477:Ions; D009682:Magnetic Resonance Spectroscopy; D011794:Quercetin / Q000032:analysis* / Q000737:chemistry; D051381:Rats; D015203:Reproducibility of Results; D012431:Rutin / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared; D013696:Temperature; D013818:Thermogravimetry; D013997:Time Factors; D047392:beta-Cyclodextrins / Q000737:chemistry*
D003432:Cross-Linking Reagents; D003505:Cyclodextrins; D007477:Ions; D047392:beta-Cyclodextrins; C041953:cyclodextrin polymer; D012431:Rutin; D002482:Cellulose; D011794:Quercetin; C031215:betadex
Inclusion interactions; Quercetin; Solid-phase extraction; β-Cyclodextrin cross-linked polymer