Treatment strategies for myeloid growth factors and intravenous iron: when, what, and how?
Myeloid growth factors can reduce the risk of chemotherapy-induced neutropenia (CIN) and thus impact the survival of patients with cancer. Patients should be assessed for risk, taking into consideration patient-related risk factors and chemotherapy regimens. Patients stratified as having at least a 20% risk for CIN should be considered for prophylactic growth factors. The NCCN Guidelines for Myeloid Growth Factors provide category 1 recommendations for the daily use of filgrastim, tbo-filgrastim, and pegfilgrastim. Cancer-related anemia can be treated with erythropoiesis-stimulating agents, red blood cell transfusion, or intravenous iron.
Presented by Jeffrey Crawford, MD, Chief, Division of Medical Oncology, Professor of Medicine, Duke Cancer Institute, Durham, North Carolina, and George M. Rodgers, MD, PhD, Professor of Medicine, Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah.
Jeffrey
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Crawford
Presented by Jeffrey Crawford, MD, Chief, Division of Medical Oncology, Professor of Medicine, Duke Cancer Institute, Durham, North Carolina, and George M. Rodgers, MD, PhD, Professor of Medicine, Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah.
George M
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Rodgers
D000740:Anemia / Q000139:chemically induced* / Q000188:drug therapy*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D064146:Chemotherapy-Induced Febrile Neutropenia / Q000188:drug therapy* / Q000517:prevention & control; D003115:Colony-Stimulating Factors / Q000627:therapeutic use*; D006801:Humans; D007501:Iron / Q000008:administration & dosage*; D009369:Neoplasms / Q000150:complications* / Q000188:drug therapy; D017410:Practice Guidelines as Topic; D018570:Risk Assessment
D003115:Colony-Stimulating Factors; D007501:Iron