Ambient air pollution and daily outpatient visits for cardiac arrhythmia in Shanghai, China.
BACKGROUND
Cardiac arrhythmias are cardiac rhythm disorders that comprise an important public health problem. Few prior studies have examined the association between ambient air pollution and arrhythmias in general populations in mainland China.


METHODS
We performed a time-series analysis to investigate the short-term association between air pollution (particulate matter with an aerodynamic diameter less than 10 µm [PM10], sulfur dioxide [SO2], and nitrogen dioxide [NO2]) and outpatient visits for arrhythmia in Shanghai, China. We applied the over-dispersed Poisson generalized additive model to analyze the associations after control for seasonality, day of the week, and weather conditions. We then stratified the analyses by age, gender, and season.


RESULTS
We identified a total of 56 940 outpatient visits for cardiac arrhythmia. A 10-µg/m3 increase in the present-day concentrations of PM10, SO2, and NO2 corresponded to increases of 0.56% (95% CI 0.42%, 0.70%), 2.07% (95% CI 1.49%, 2.64%), and 2.90% (95% CI 2.53%, 3.27%), respectively, in outpatient arrhythmia visits. The associations were stronger in older people (aged ≥65 years) and in females. This study provides the first evidence that ambient air pollution is significantly associated with increased risk of cardiac arrhythmia in mainland China.


CONCLUSIONS
Our analyses provide evidence that the current air pollution levels have an adverse effect on cardiovascular health and strengthened the rationale for further limiting air pollution levels in the city.
School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Institute of Global Health, Fudan University.
Ang
A
Zhao
Renjie
R
Chen
Xingya
X
Kuang
Haidong
H
Kan
D000368:Aged; D000393:Air Pollutants / Q000009:adverse effects* / Q000032:analysis; D000397:Air Pollution / Q000009:adverse effects* / Q000032:analysis; D000553:Ambulatory Care / Q000706:statistics & numerical data*; D001145:Arrhythmias, Cardiac / Q000209:etiology* / Q000628:therapy*; D002681:China; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016012:Poisson Distribution; D018570:Risk Assessment; D013997:Time Factors
D000393:Air Pollutants