Prevalence of viral hepatitis in Croatian adult population undergoing routine check-up, 2010-2011.
Seroprevalence data on viral hepatitis in the general population vary widely. The aim of this study was to determine the prevalence of hepatitis A (HAV), hepatitis B (HBV) and hepatitis C (HCV) viruses in the general Croatian adult population undergoing routine check-ups. The seroprevalence of anti-HAV, anti-HBc and anti-HCV was 40.5%, 7.0% and 0.9%, respectively. HBsAg was found in 0.7% and anti-HBs antibodies in 24.4% of participants. Gender was not associated with HAV, HBV or HCV seropositivity. HAV and HBV seropositivity increased progressively with age (HAV from 11.7% to 90.4%, p < 0.001; HBV from 1.7% to 15.8%, p < 0.001). Participants from rural areas showed a significantly higher HBV seroprevalence rate than those from urban areas (10.7% vs. 6.1%, p = 0.007). Results of univariate and multiple logistic regression showed that older age was a significant predictor for both HAV and HBV seropositivity while rural place of residence was a significant predictor for HBV seropositivity.
Tatjana
T
Vilibić-Cavlek
Jasmina
J
Kucinar
Suncanica
S
Ljubin-Sternak
Bernard
B
Kaić
Lorena
L
Lazarić-Stefanović
Branko
B
Kolarić
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017523:Croatia / Q000453:epidemiology; D003955:Diagnostic Tests, Routine; D005260:Female; D035922:Hepatitis A Antibodies / Q000097:blood / Q000276:immunology; D006510:Hepatitis B Antibodies / Q000097:blood / Q000276:immunology; D018937:Hepatitis C Antibodies / Q000097:blood / Q000276:immunology; D006525:Hepatitis, Viral, Human / Q000097:blood / Q000453:epidemiology* / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010808:Physical Examination / Q000379:methods; D015995:Prevalence; D012423:Rural Health / Q000706:statistics & numerical data*; D016036:Seroepidemiologic Studies; D014504:Urban Health / Q000706:statistics & numerical data; D055815:Young Adult
D035922:Hepatitis A Antibodies; D006510:Hepatitis B Antibodies; D018937:Hepatitis C Antibodies