Neuroendocrine carcinoma of the stomach: A case report.
Neuroendocrine carcinoma (NEC) is a rare tumor, comprising < 1% of stomach cancers. A 55-year-old woman was referred to our hospital with biopsy-proven gastric cancer. A shallow ulcerative lesion was detected in the lesser curvature of the lower body. It was suspected to be early gastric cancer IIA + IIC type. Thus, endoscopic submucosal dissection was performed. She was subsequently diagnosed with NEC, which is aggressive and carries a poor prognosis. We conducted a radical resection and a laparoscopic-assisted distal gastrectomy. The tumor had infiltrated the subserosal layer and 6/42 lymph nodes were involved. The mitotic index was 16/10 high power fields and the Ki-67 labeling index was 26%-50%. The final diagnosis of NEC was made according to the World Health Organization 2010 criteria. She was suspected of having jumping metastasis to the proximal margin. The patient was treated with an oral anticancer drug (5-flurouracil based drug) for 2 years. The patient has been followed up for 3 years without recurrence.
Sang Hyun Kang, Kwang Hee Kim, Sang Hyuk Seo, Min Sung An, Tae Kwun Ha, Ha Kyung Park, Ki Beom Bae, Chang Soo Choi, Sang Hun Oh, Young Kil Choi, Department of Surgery, Busan Paik Hospital, Inje University College of Medicine, Busan 614-735, South Korea.
Sang Hyun
SH
Kang
Sang Hyun Kang, Kwang Hee Kim, Sang Hyuk Seo, Min Sung An, Tae Kwun Ha, Ha Kyung Park, Ki Beom Bae, Chang Soo Choi, Sang Hun Oh, Young Kil Choi, Department of Surgery, Busan Paik Hospital, Inje University College of Medicine, Busan 614-735, South Korea.
Kwang Hee
KH
Kim
Sang Hyun Kang, Kwang Hee Kim, Sang Hyuk Seo, Min Sung An, Tae Kwun Ha, Ha Kyung Park, Ki Beom Bae, Chang Soo Choi, Sang Hun Oh, Young Kil Choi, Department of Surgery, Busan Paik Hospital, Inje University College of Medicine, Busan 614-735, South Korea.
Sang Hyuk
SH
Seo
Sang Hyun Kang, Kwang Hee Kim, Sang Hyuk Seo, Min Sung An, Tae Kwun Ha, Ha Kyung Park, Ki Beom Bae, Chang Soo Choi, Sang Hun Oh, Young Kil Choi, Department of Surgery, Busan Paik Hospital, Inje University College of Medicine, Busan 614-735, South Korea.
Min Sung
MS
An
Sang Hyun Kang, Kwang Hee Kim, Sang Hyuk Seo, Min Sung An, Tae Kwun Ha, Ha Kyung Park, Ki Beom Bae, Chang Soo Choi, Sang Hun Oh, Young Kil Choi, Department of Surgery, Busan Paik Hospital, Inje University College of Medicine, Busan 614-735, South Korea.
Tae Kwun
TK
Ha
Sang Hyun Kang, Kwang Hee Kim, Sang Hyuk Seo, Min Sung An, Tae Kwun Ha, Ha Kyung Park, Ki Beom Bae, Chang Soo Choi, Sang Hun Oh, Young Kil Choi, Department of Surgery, Busan Paik Hospital, Inje University College of Medicine, Busan 614-735, South Korea.
Ha Kyung
HK
Park
Sang Hyun Kang, Kwang Hee Kim, Sang Hyuk Seo, Min Sung An, Tae Kwun Ha, Ha Kyung Park, Ki Beom Bae, Chang Soo Choi, Sang Hun Oh, Young Kil Choi, Department of Surgery, Busan Paik Hospital, Inje University College of Medicine, Busan 614-735, South Korea.
Ki Beom
KB
Bae
Sang Hyun Kang, Kwang Hee Kim, Sang Hyuk Seo, Min Sung An, Tae Kwun Ha, Ha Kyung Park, Ki Beom Bae, Chang Soo Choi, Sang Hun Oh, Young Kil Choi, Department of Surgery, Busan Paik Hospital, Inje University College of Medicine, Busan 614-735, South Korea.
Chang Soo
CS
Choi
Sang Hyun Kang, Kwang Hee Kim, Sang Hyuk Seo, Min Sung An, Tae Kwun Ha, Ha Kyung Park, Ki Beom Bae, Chang Soo Choi, Sang Hun Oh, Young Kil Choi, Department of Surgery, Busan Paik Hospital, Inje University College of Medicine, Busan 614-735, South Korea.
Sang Hun
SH
Oh
Sang Hyun Kang, Kwang Hee Kim, Sang Hyuk Seo, Min Sung An, Tae Kwun Ha, Ha Kyung Park, Ki Beom Bae, Chang Soo Choi, Sang Hun Oh, Young Kil Choi, Department of Surgery, Busan Paik Hospital, Inje University College of Medicine, Busan 614-735, South Korea.
Young Kil
YK
Choi
Gastrectomy; Ki-67; Mitosis; Neuroendocrine carcinoma; Prognosis