The development of pulmonary aspergillosis and pneumothorax in a patient with neutropenic systemic lupus erythematosus and successful treatment of the first case.
There are reports on patients with systemic lupus erythematosus (SLE) with aspergillosis; however, aspergillosis-related pneumothorax has not been reported in SLE. We present a female patient with active SLE who was administered high-dose steroids, developed an opportunistic bacterial infection and had a cavitary pulmonary lesion. Sputum cultures yielded Aspergillus fumigatus. She was administered voriconazole. She developed dyspnoea and chest X-ray showed pneumothorax. She was placed with an underwater drainage chest tube; the pneumothorax and the pulmonary lesion regressed.
Department of Rheumatology, Trakya University Medical Faculty, Edirne, Turkey.
Omer Nuri
ON
Pamuk
Department of Hematology, Trakya University Medical Faculty, Edirne, Turkey.
Gulsum Emel
GE
Pamuk
Department of Internal Medicine, Trakya University Medical Faculty, Edirne, Turkey.
Ebru
E
Barutcu
Department of Infectious Diseases, Trakya University Medical Faculty, Edirne, Turkey.
Aygul Dogan
AD
Celik
D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D000935:Antifungal Agents / Q000627:therapeutic use; D001232:Aspergillus fumigatus; D004322:Drainage; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000188:drug therapy*; D009503:Neutropenia / Q000150:complications; D009894:Opportunistic Infections / Q000188:drug therapy / Q000382:microbiology*; D011030:Pneumothorax / Q000382:microbiology / Q000628:therapy; D011239:Prednisolone / Q000008:administration & dosage; D055732:Pulmonary Aspergillosis / Q000188:drug therapy / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology; D013211:Staphylococcus aureus; D065819:Voriconazole / Q000627:therapeutic use; D055815:Young Adult
D000893:Anti-Inflammatory Agents; D000935:Antifungal Agents; D011239:Prednisolone; D065819:Voriconazole