Hereditary hyperbilirubinemias.
Inherited disorders of bilirubin metabolism involve four autosomal recessive syndromes: Gilbert, CriglerNajjar, Dubin-Johnson and Rotor, among which the first two are characterized by unconjugated and the second two by conjugated hyperbilirubinemia. Gilbert syndrome occurs in 2%-10% of general population, while others are rare. Except for Crigler-Najjar syndrome, hereditary hyperbilirubinemias belong to benign disorders and thus no treatment is required.
Nedeljko
N
Radlović
D001663:Bilirubin / Q000235:genetics / Q000378:metabolism; D003414:Crigler-Najjar Syndrome / Q000453:epidemiology / Q000235:genetics / Q000628:therapy; D005878:Gilbert Disease / Q000453:epidemiology / Q000235:genetics / Q000628:therapy; D006801:Humans; D006932:Hyperbilirubinemia / Q000453:epidemiology / Q000235:genetics / Q000628:therapy; D006933:Hyperbilirubinemia, Hereditary / Q000145:classification / Q000453:epidemiology / Q000235:genetics / Q000628:therapy
D001663:Bilirubin