Developmental biology of Cystoisospora (Apicomplexa: Sarcocystidae) monozoic tissue cysts.
Tissue cyst stages are an intriguing aspect of the developmental cycle and transmission of species of Sarcocystidae. Tissue-cyst stages of Toxoplasma, Hammondia, Neospora, Besnoitia, and Sarcocystis contain many infectious stages (bradyzoites). The tissue cyst stage of Cystoisospora (syn. Isospora) possesses only 1 infectious stage (zoite), and is therefore referred to as a monozoic tissue cyst (MZTC). No tissue cyst stages are presently known for members of Nephroisospora. The present report examines the developmental biology of MZTC stages of Cystoisospora Frenkel, 1977 . These parasites cause intestinal coccidiosis in cats, dogs, pigs, and humans. The MZTC stages of C. belli are believed to be associated with reoccurrence of clinical disease in humans.
Department of Biomedical Science and Pathology, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, 1410 Prices Fork Road, Blacksburg, Virginia 24061.
David S
DS
Lindsay
Alice E
AE
Houk
Sheila M
SM
Mitchell
J P
JP
Dubey
D000818:Animals; D001681:Biological Assay; D003048:Coccidiosis / Q000469:parasitology* / Q000635:transmission; D006801:Humans; D007411:Intestinal Diseases, Parasitic / Q000469:parasitology* / Q000635:transmission; D008018:Life Cycle Stages; D021745:Sarcocystidae / Q000145:classification / Q000254:growth & development*