Retroperitoneal paragangliomas: Report of 4 cases.
We reviewed the data of all patients managed for retroperitoneal paragangliomas (PGLs) between June 2010 and June 2011 to present our experience concerning this uncommon entity to highlight diagnostic and therapeutic challenges of retroperitoneal PGLs. All patients were admitted to the department of general and hepatobiliary surgery in the regional hospital of Jendouba, Tunisia. The size of the tumor was taken at its largest dimension, as determined in a computed tomography (CT) scan and pathological reports. There were 4 patients (all women) with a median age of 48 years (range 46-56 years). Abdominal pain was the commonest presentation. CT showed and localized the tumors which were all retroperitoneal. All patients had successful surgical resection of the tumors under invasive arterial blood pressure monitoring. One patient underwent surgery for a presumed tumor of the pancreatic head. The fresh-mount microscopic study of the peroperative biopsy yielded inflammatory tissue without malignancy and no resection was performed. Final histological examination of the biopsy concluded PGL. A second laparotomy was performed and the tumor was entirely resected. The diagnosis was made after surgery by histology in all patients. The control of the blood pressure was improved after surgery in 3 patients. Paragangliomas are rare tumors. The retroperitoneal localization is uncommon. Complete surgical resection remains the only curative treatment but it is often challenging as these tumors are located near multiple vital blood vessels.
Helmi Kallel, Hassen Hentati, Amine Baklouti, Ali Gassara, Ahmed Saadaoui, Ghassen Halek, Sana Landolsi, MA El Ouaer, Wajdi Chaieb, Saber Mannaï, Department of Visceral Surgery, Hospital of Jendouba, Faculty of Medicine of Tunis, University of Tunis El Manar, 2083 Ariana, Tunis.
Helmi
H
Kallel
Helmi Kallel, Hassen Hentati, Amine Baklouti, Ali Gassara, Ahmed Saadaoui, Ghassen Halek, Sana Landolsi, MA El Ouaer, Wajdi Chaieb, Saber Mannaï, Department of Visceral Surgery, Hospital of Jendouba, Faculty of Medicine of Tunis, University of Tunis El Manar, 2083 Ariana, Tunis.
Hassen
H
Hentati
Helmi Kallel, Hassen Hentati, Amine Baklouti, Ali Gassara, Ahmed Saadaoui, Ghassen Halek, Sana Landolsi, MA El Ouaer, Wajdi Chaieb, Saber Mannaï, Department of Visceral Surgery, Hospital of Jendouba, Faculty of Medicine of Tunis, University of Tunis El Manar, 2083 Ariana, Tunis.
Amine
A
Baklouti
Helmi Kallel, Hassen Hentati, Amine Baklouti, Ali Gassara, Ahmed Saadaoui, Ghassen Halek, Sana Landolsi, MA El Ouaer, Wajdi Chaieb, Saber Mannaï, Department of Visceral Surgery, Hospital of Jendouba, Faculty of Medicine of Tunis, University of Tunis El Manar, 2083 Ariana, Tunis.
Ali
A
Gassara
Helmi Kallel, Hassen Hentati, Amine Baklouti, Ali Gassara, Ahmed Saadaoui, Ghassen Halek, Sana Landolsi, MA El Ouaer, Wajdi Chaieb, Saber Mannaï, Department of Visceral Surgery, Hospital of Jendouba, Faculty of Medicine of Tunis, University of Tunis El Manar, 2083 Ariana, Tunis.
Ahmed
A
Saadaoui
Helmi Kallel, Hassen Hentati, Amine Baklouti, Ali Gassara, Ahmed Saadaoui, Ghassen Halek, Sana Landolsi, MA El Ouaer, Wajdi Chaieb, Saber Mannaï, Department of Visceral Surgery, Hospital of Jendouba, Faculty of Medicine of Tunis, University of Tunis El Manar, 2083 Ariana, Tunis.
Ghassen
G
Halek
Helmi Kallel, Hassen Hentati, Amine Baklouti, Ali Gassara, Ahmed Saadaoui, Ghassen Halek, Sana Landolsi, MA El Ouaer, Wajdi Chaieb, Saber Mannaï, Department of Visceral Surgery, Hospital of Jendouba, Faculty of Medicine of Tunis, University of Tunis El Manar, 2083 Ariana, Tunis.
Sana
S
Landolsi
Helmi Kallel, Hassen Hentati, Amine Baklouti, Ali Gassara, Ahmed Saadaoui, Ghassen Halek, Sana Landolsi, MA El Ouaer, Wajdi Chaieb, Saber Mannaï, Department of Visceral Surgery, Hospital of Jendouba, Faculty of Medicine of Tunis, University of Tunis El Manar, 2083 Ariana, Tunis.
Ma El
ME
Ouaer
Helmi Kallel, Hassen Hentati, Amine Baklouti, Ali Gassara, Ahmed Saadaoui, Ghassen Halek, Sana Landolsi, MA El Ouaer, Wajdi Chaieb, Saber Mannaï, Department of Visceral Surgery, Hospital of Jendouba, Faculty of Medicine of Tunis, University of Tunis El Manar, 2083 Ariana, Tunis.
Wajdi
W
Chaieb
Helmi Kallel, Hassen Hentati, Amine Baklouti, Ali Gassara, Ahmed Saadaoui, Ghassen Halek, Sana Landolsi, MA El Ouaer, Wajdi Chaieb, Saber Mannaï, Department of Visceral Surgery, Hospital of Jendouba, Faculty of Medicine of Tunis, University of Tunis El Manar, 2083 Ariana, Tunis.
Fethia
F
Maamouri
Helmi Kallel, Hassen Hentati, Amine Baklouti, Ali Gassara, Ahmed Saadaoui, Ghassen Halek, Sana Landolsi, MA El Ouaer, Wajdi Chaieb, Saber Mannaï, Department of Visceral Surgery, Hospital of Jendouba, Faculty of Medicine of Tunis, University of Tunis El Manar, 2083 Ariana, Tunis.
Saber
S
Mannaï
Extra adrenal pheochromocytoma, Retroperitoneal; Histology; Paraganglioma; Surgery