Long-term maternal morbidity and mortality associated with ischemic placental disease.
Ischemic placental disease can have long-term maternal health implications. In this article, we discuss the three conditions of ischemic placental disease (preeclampsia, fetal growth restriction, and abruption placenta) and its associated long-term maternal morbidity. Retrospective observational studies comparing pregnancies complicated by ischemic placental disease to uncomplicated pregnancies suggest an increased long-term risk of hypertension, cardiovascular death, metabolic syndrome, and cerebrovascular disease. This association is much stronger in women who had an indicated-preterm delivery due to ischemic placental disease. It is important to adequately counsel women who are diagnosed with these conditions about their future health risks. Increased awareness of the potential health risks and multidisciplinary collaboration remains paramount to instituting the appropriate screening and preventative strategies (i.e., behavior modification) for affected women.
Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Winthrop-University Hospital, 259 First St, Mineola, NY 11501.
Tracy
T
Adams
Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Winthrop-University Hospital, 259 First St, Mineola, NY 11501.
Corinne
C
Yeh
Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Winthrop-University Hospital, 259 First St, Mineola, NY 11501.
Nadia
N
Bennett-Kunzier
Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Winthrop-University Hospital, 259 First St, Mineola, NY 11501. Electronic address: wkinzler@winthrop.org.
Wendy L
WL
Kinzler
D000037:Abruptio Placentae / Q000503:physiopathology; D002318:Cardiovascular Diseases / Q000209:etiology / Q000401:mortality; D002561:Cerebrovascular Disorders / Q000209:etiology / Q000401:mortality; D002908:Chronic Disease; D005260:Female; D005317:Fetal Growth Retardation / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000401:mortality; D007511:Ischemia / Q000150:complications* / Q000401:mortality / Q000503:physiopathology*; D008428:Maternal Mortality; D024821:Metabolic Syndrome / Q000209:etiology / Q000401:mortality; D009035:Mothers / Q000706:statistics & numerical data*; D010920:Placenta / Q000098:blood supply*; D010922:Placenta Diseases / Q000401:mortality / Q000503:physiopathology*; D011225:Pre-Eclampsia / Q000503:physiopathology; D011247:Pregnancy; D012189:Retrospective Studies; D012307:Risk Factors
Fetal growth restriction; Ischemic placental disease; Long term maternal morbidity; Placental abruption; Preeclampsia