Evaluation of antibody frequency against HBV, HCV and HTLV-1.
OBJECTIVE
This study was designed to evaluate the frequency of antibody against these viruses in individuals attending the endoscopy ward of Taleghani hospital Tehran, Iran.


BACKGROUND
Blood-borne viruses such as hepatitis B and hepatitis C virus and HTLV-1 virus are among the world's public health problems. Hepatitis viruses cause liver problems and HTLV-1 infection can lead to adult T-Cell lymphoma (ATL).


METHODS
Blood samples of 219 individuals attending the endoscopy ward of Taleghani hospital between years 2009-2011 were collected. A questionnaire containing demographic data was completed for each subject. Blood samples were tested for antibody against HTLV-1, HCV and HBc by ELISA (Dia.pro Italy). In case of positive results for anti-HBc, samples were also tested for HBs Ag antigen.


RESULTS
Ninety two subjects were male and 127 were female. Mean age of the population was 39.87 ± 16.47. None of the subjects had anti-HCV antibody, while 4 of them had anti-HTLV-1 antibody and 26 anti-HBc antibody; which only two of these individuals had HBs Antibody.


CONCLUSIONS
The results of this study show that frequency of anti-HCV and anti-HTLV-1 antibodies are very low, while the frequency of anti-HBc was higher in the population. Since HTLV-1 is the causative agent of a type of blood cancer, it seems that screening of donated bloods in this region should be considered.
Gastroenterology and Liver Diseases Research center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Seyed Mohammad Ebrahim
SM
Tahaei
Gastroenterology and Liver Diseases Research center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Seyed Reza
SR
Mohebbi
Gastroenterology and Liver Diseases Research center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Seyed Reza
SR
Fatemi
Gastroenterology and Liver Diseases Research center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Pedram
P
Azimzadeh
Gastroenterology and Liver Diseases Research center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Dariush
D
Mirsattari
Gastroenterology and Liver Diseases Research center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Azar
A
Sanati
Gastroenterology and Liver Diseases Research center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Afsaneh
A
Sharifian
Frequency; HTLV-1; Hepatitis B virus; Hepatitis C virus