Assessing motor outcome and functional recovery following nerve injury.
Behavioral tests significantly contribute to our understanding of nerve function after experimental lesions and/or therapeutic intervention. In particular, the rat sciatic nerve has proven to be a valuable animal model to study nerve injury and repair. Here, we describe how to optimally use the commercially available CatWalk system to obtain a detailed and objective analysis of dynamic and static gait parameters.
Institute of Neuroscience, Université Catholique de Louvain (U.C.L.), Brussels, Belgium, deumensr@gmail.com.
Ronald
R
Deumens
Claudia
C
Marinangeli
Ahmet
A
Bozkurt
Gary Anthony
GA
Brook
D000818:Animals; D004195:Disease Models, Animal; D005684:Gait; D009042:Motivation; D009416:Nerve Regeneration; D051381:Rats; D011917:Rats, Inbred Lew; D017207:Rats, Sprague-Dawley; D017208:Rats, Wistar; D020127:Recovery of Function; D012584:Sciatic Nerve / Q000293:injuries / Q000502:physiology* / Q000503:physiopathology*; D020426:Sciatic Neuropathy / Q000503:physiopathology*; D012984:Software