Regression of metastatic colon tumour from primary adenocarcinoma of the lung due to fistulisation to the bowel lumen.
An 80-year-old Japanese male was diagnosed with pulmonary adenocarcinoma. The patient exhibited extensive extra pulmonary involvement in the bone, adrenal gland, abdominal lymph nodes, and sigmoid colon. A single course of chemotherapy with carboplatin and pemetrexed was administered as the first-line treatment. Subsequently, the patient received pemetrexed monotherapy. Two months after the diagnosis, rapid regression of the metastatic tumour in the sigmoid colon was observed. Based on the findings of CT scanning and colonoscopic examination, tumour-bowel fistulisation was considered to be a cause of the rapid regression. This case report illustrates a tumour-bowel fistula of a colonic metastatic tumour in a patient with lung cancer. Radiographic and endoscopic features of the rare manifestation are presented.
Department of Gastroenterology, Onomichi Municipal Hospital, Onomichi 722-8503, Japan ; Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan.
Masaya
M
Iwamuro
Department of Gastroenterology, Onomichi Municipal Hospital, Onomichi 722-8503, Japan.
Yoshio
Y
Miyabe
Department of Gastroenterology, Onomichi Municipal Hospital, Onomichi 722-8503, Japan.
Kai
K
Hanae
Department of Gastroenterology, Onomichi Municipal Hospital, Onomichi 722-8503, Japan.
Kawai
K
Yoshinari
Department of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan.
Takata
T
Katsuyoshi
Department of Respiratory Medicine, Onomichi Municipal Hospital, Onomichi 722-8503, Japan.
Toshi
T
Murakami
Department of Radiology, Onomichi Municipal Hospital, Onomichi 722-8503, Japan.
Mifune
M
Hirofumi
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan.
Kazuhide
K
Yamamoto
colonic metastasis; lung cancer; pulmonary adenocarcinoma; tumour-bowel fistula