Acute effects of air pollution on asthma hospitalization in Shanghai, China.
Air pollution has been accepted as an important contributor to asthma development and exacerbation. However, the evidence is limited in China. In this study, we investigated the acute effect of air pollution on asthma hospitalization in Shanghai, China. We applied over-dispersed generalized additive model adjusted for weather conditions, day of the week, long-term and seasonal trends. An interquartile range increase in the moving average concentrations of PM10, SO2, NO2 and BC on the concurrent day and previous day corresponded to 1.82%, 6.41%, 8.26% and 6.62% increase of asthmatic hospitalization, respectively. The effects of SO2 and NO2 were robust after adjustment for PM10. The associations appeared to be more evident in the cool season than in the warm season. Our results contribute to the limited data in the scientific literature on acute effects of air pollution on asthma in high exposure settings, which are typical in developing countries.
School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China.
Jing
J
Cai
School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China.
Ang
A
Zhao
School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China.
Jinzhuo
J
Zhao
School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China; Research Institute for the Changing Global Environment and Fudan Tyndall Centre, Fudan University, Shanghai, China; Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP(3)), Fudan University, 130 Dong-An Road, Shanghai 200433, China.
Renjie
R
Chen
School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China.
Weibing
W
Wang
Department of Epidemiology, College of Public Health and Health Professional and College of Medicine, University of Florida, Gainesville, FL, USA.
Sandie
S
Ha
Department of Epidemiology, College of Public Health and Health Professional and College of Medicine, University of Florida, Gainesville, FL, USA.
Xiaohui
X
Xu
School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China; Research Institute for the Changing Global Environment and Fudan Tyndall Centre, Fudan University, Shanghai, China; Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP(3)), Fudan University, 130 Dong-An Road, Shanghai 200433, China. Electronic address: haidongkan@gmail.com.
Haidong
H
Kan
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000393:Air Pollutants / Q000032:analysis*; D001249:Asthma / Q000453:epidemiology*; D002244:Carbon / Q000032:analysis; D002681:China / Q000453:epidemiology; D002947:Cities / Q000706:statistics & numerical data; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D008962:Models, Theoretical; D009569:Nitric Oxide / Q000032:analysis; D012621:Seasons; D013458:Sulfur Dioxide / Q000032:analysis; D014887:Weather; D055815:Young Adult
D000393:Air Pollutants; D013458:Sulfur Dioxide; D009569:Nitric Oxide; D002244:Carbon
Air pollution; Asthma hospitalization; Black carbon; Time series