Outcomes of surgical aortic valve replacement: the benchmark for percutaneous therapies.
Historically, many patients with severe senile calcific aortic valve stenosis (AS) were not offered surgery, largely due to the perception that the risks of operation were prohibitive. Such patients have subsequently been formally designated as 'high risk' or 'inoperable' with respect to their suitability for surgical aortic valve replacement (SAVR) in the evolving lexicon of heart valve disease. The recent availability of transcatheter aortic valve replacement (TAVR) represents an alternative treatment option, and permits the opportunity to re-examine algorithms for assessing operative risk. As the experience with TAVR grows, expanded use in new patient populations can be anticipated. While TAVR in high risk AS patients has demonstrated benefits, the emerging indication in intermediate AS is less clear and conclusions will necessarily await the availability of results from ongoing clinical trials. This article will discuss current outcomes for SAVR among high- and intermediate-risk patients with AS as a barometer in assessing the results of nascent percutaneous therapies.
Division of Cardiovascular Surgery, Department of Surgery, Mayo Clinic, Rochester, MN.
Pietro
P
Bajona
Division of Cardiovascular Surgery, Department of Surgery, Mayo Clinic, Rochester, MN. Electronic address: suri.rakesh@mayo.edu.
Rakesh M
RM
Suri
Division of Cardiovascular Surgery, Department of Surgery, Mayo Clinic, Rochester, MN.
Kevin L
KL
Greason
Division of Cardiovascular Surgery, Department of Surgery, Mayo Clinic, Rochester, MN.
Hartzell V
HV
Schaff
D001021:Aortic Valve / Q000473:pathology* / Q000601:surgery; D001024:Aortic Valve Stenosis / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D019985:Benchmarking / Q000592:standards*; D002114:Calcinosis / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D006328:Cardiac Catheterization / Q000009:adverse effects / Q000592:standards*; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000592:standards*; D006801:Humans; D010043:Outcome and Process Assessment, Health Care / Q000592:standards*; D017410:Practice Guidelines as Topic; D019984:Quality Indicators, Health Care / Q000592:standards*; D018570:Risk Assessment; D012307:Risk Factors; D012720:Severity of Illness Index; D016896:Treatment Outcome
Aortic stenosis; Aortic valve replacement; Surgery; Transcatheter aortic valve replacement