Short-term efficacy of laparoscopy-assisted vs open radical gastrectomy in gastric cancer.
OBJECTIVE
To investigate the short-term benefits of laparoscopic radical gastrectomy (LARG) and open radical gastrectomy (ORG) in patients with gastric cancer.


METHODS
A total of 400 patients with gastric cancer aged ≤ 65 years who were treated at General Hospital of Lanzhou Military Region were enrolled. Among these, 200 patients underwent LARG between October 2008 and August 2012 (LARG group); and 200 patients underwent ORG between March 2000 and September 2008 (ORG group). The short-term therapeutic benefits between the two groups were analyzed.


RESULTS
The LARG procedure offered significantly better benefits to the patients compared to the ORG procedure, including less intraoperative blood loss (103.1 ± 19.5 mL vs 163.0 ± 32.9 mL, P < 0.0001), shorter postoperative hospital stay (6.8 ± 1.2 d vs 9.5 ± 1.6 d, P < 0.0001), less frequent occurrence of postoperative complications (6.5% vs 13.5%, P = 0.02), shorter time to mobilization (1.0 ± 0.3 vs 3.3 ± 0.4 d, P < 0.0001), shorter time to bowel opening (3.3 ± 0.7 d vs 4.5 ± 0.7 d, P < 0.0001), and shorter time to normal diet (3.0 ± 0.4 vs d 3.8 ± 0.5 d, P < 0.0001). However, LARG required a longer time to complete than the ORG procedure (192.3 ± 20.9 min vs 180.0 ± 26.9 min, P < 0.0001).


CONCLUSIONS
Compared to ORG, LARG is safer, more effective, and less invasive for treating gastric cancer, with better short-term efficacy.
Hong-Tao Li, Xiao-Peng Han, Lin Su, Wan-Kun Zhu, Wei Xu, Kun Li, Hong-Bin Liu, Department of General Surgery, General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu Province, China.
Hong-Tao
HT
Li
Hong-Tao Li, Xiao-Peng Han, Lin Su, Wan-Kun Zhu, Wei Xu, Kun Li, Hong-Bin Liu, Department of General Surgery, General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu Province, China.
Xiao-Peng
XP
Han
Hong-Tao Li, Xiao-Peng Han, Lin Su, Wan-Kun Zhu, Wei Xu, Kun Li, Hong-Bin Liu, Department of General Surgery, General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu Province, China.
Lin
L
Su
Hong-Tao Li, Xiao-Peng Han, Lin Su, Wan-Kun Zhu, Wei Xu, Kun Li, Hong-Bin Liu, Department of General Surgery, General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu Province, China.
Wan-Kun
WK
Zhu
Hong-Tao Li, Xiao-Peng Han, Lin Su, Wan-Kun Zhu, Wei Xu, Kun Li, Hong-Bin Liu, Department of General Surgery, General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu Province, China.
Wei
W
Xu
Hong-Tao Li, Xiao-Peng Han, Lin Su, Wan-Kun Zhu, Wei Xu, Kun Li, Hong-Bin Liu, Department of General Surgery, General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu Province, China.
Kun
K
Li
Hong-Tao Li, Xiao-Peng Han, Lin Su, Wan-Kun Zhu, Wei Xu, Kun Li, Hong-Bin Liu, Department of General Surgery, General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu Province, China.
Qing-Chuan
QC
Zhao
Hong-Tao Li, Xiao-Peng Han, Lin Su, Wan-Kun Zhu, Wei Xu, Kun Li, Hong-Bin Liu, Department of General Surgery, General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu Province, China.
Hua
H
Yang
Hong-Tao Li, Xiao-Peng Han, Lin Su, Wan-Kun Zhu, Wei Xu, Kun Li, Hong-Bin Liu, Department of General Surgery, General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu Province, China.
Hong-Bin
HB
Liu
Gastric cancer; Laparoscopic surgery; Open surgery; Short-term efficacy