Beyond the intensive care unit bundle: Implementation of a successful hospital-wide initiative to reduce central line-associated bloodstream infections.
A multimodal hospital-wide central line-associated bloodstream infection (CLABSI) risk reduction strategy was implemented over a 20-month period at an Australian center. Reduced CLABSI rates were observed in both intensive care units (ICUs) (incidence rate ratio [IRR], 0.39; P < .001) and non-ICU wards (IRR, 0.54; P < .001). The median time to CLABSI onset was 7.5 days for ICU events and 13 days for non-ICU events. The timing of infection demonstrates the need for more careful attention to postinsertion care and access of central venous catheters.
Infection Prevention and Healthcare Epidemiology Unit, Alfred Health, Melbourne, Australia. Electronic address: g.klintworth@alfred.org.au.
Gemma
G
Klintworth
Infection Prevention and Healthcare Epidemiology Unit, Alfred Health, Melbourne, Australia.
Jane
J
Stafford
Infection Prevention and Healthcare Epidemiology Unit, Alfred Health, Melbourne, Australia.
Mark
M
O'Connor
Intensive Care Unit, Alfred Hospital, Melbourne, Australia.
Tim
T
Leong
Medical Services, Alfred Health, Melbourne, Australia.
Lee
L
Hamley
Infection Prevention and Healthcare Epidemiology Unit, Alfred Health, Melbourne, Australia.
Kerrie
K
Watson
Infection Prevention and Healthcare Epidemiology Unit, Alfred Health, Melbourne, Australia.
Jacqueline
J
Kennon
Infection Prevention and Healthcare Epidemiology Unit, Alfred Health, Melbourne, Australia.
Pauline
P
Bass
Infection Prevention and Healthcare Epidemiology Unit, Alfred Health, Melbourne, Australia.
Allen C
AC
Cheng
Infection Prevention and Healthcare Epidemiology Unit, Alfred Health, Melbourne, Australia.
Leon J
LJ
Worth
D001315:Australia; D055499:Catheter-Related Infections / Q000517:prevention & control*; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D062905:Central Venous Catheters / Q000009:adverse effects*; D003428:Cross Infection / Q000517:prevention & control*; D006801:Humans; D017053:Infection Control / Q000379:methods* / Q000706:statistics & numerical data; D007362:Intensive Care Units / Q000706:statistics & numerical data; D064872:Patient Care Bundles; D018805:Sepsis / Q000517:prevention & control*; D062606:Tertiary Care Centers / Q000706:statistics & numerical data; D013997:Time Factors
Central venous catheter; Infection prevention; Surveillance