Salivary gland ultrasound in children: a useful tool in the diagnosis of juvenile Sjögren's syndrome.
Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease uncommon in children, clinically characterized by recurrent parotitis at the onset, which is a common disorder in childhood, most of them of infectious origin. Juvenile pSS diagnosis is based on clinical symptoms and presence of autoantibodies, after exclusion of infectious or lymphoproliferative diseases. However, salivary gland ultrasound (SGU) shows typical features of pSS that can add useful information for the diagnosis of this disorder. We describe three patients who presented with recurrent parotitis in which characteristic autoantibodies and typical SGU pattern allow us to make the diagnosis of juvenile pSS. We suggest that in children with recurrent parotitis SGU and autoantibodies should be routinely performed.
Department of Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain. juancarlos.nietog@gmail.com.
Juan Carlos
JC
Nieto-González
Indalecio
I
Monteagudo
Natalia
N
Bello
Lina
L
Martínez-Estupiñan
Esperanza
E
Naredo
Luis
L
Carreño
D017668:Age of Onset; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001323:Autoantibodies / Q000097:blood; D015415:Biomarkers / Q000097:blood; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D010309:Parotitis / Q000209:etiology; D011237:Predictive Value of Tests; D012469:Salivary Glands / Q000000981:diagnostic imaging* / Q000187:drug effects; D012859:Sjogren's Syndrome / Q000097:blood / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy; D016896:Treatment Outcome; D014463:Ultrasonography
D018501:Antirheumatic Agents; D001323:Autoantibodies; D015415:Biomarkers