Idiopathic mesenteric phlebosclerosis associated with long-term use of medical liquor: two case reports and literature review.
A 62-year-old woman was admitted to our hospital in 2011 because of recurrent abdominal pain, nausea and constipation for six months. Computed tomography enterography (CTE) showed tortuous thread-like calcifications in the ileocolic vein and right colic vein, while colonoscopy revealed purple-blue mucosa extending from the cecum to the splenic flexure. Based on the results of these tests, the patient was diagnosed with idiopathic mesenteric phlebosclerosis (IMP). She had a history of Chinese medical liquor intake for one and a half years and her symptoms subsided after conservative treatment. In 2013, a 63-year-old male patient who presented with recurrent lower right abdominal pain, bloating, melena and diarrhea for fifteen months was admitted to our institution. Colonoscopy and CTE led to the diagnosis of IMP. He also used Chinese medical liquor for approximately 12 years. The patient underwent total colectomy and the postoperative course was uneventful. We searched for previously published reports on similar cases and analyzed the clinical data of 50 cases identified in PubMed. As some of these patients admitted use of Chinese medicines, we hypothesize that Chinese medicines may play a role in the pathogenesis of IMP.
Fang Guo, Yu-Fen Zhou, Fan Zhang, Yao-Zong Yuan, Wei-Yan Yao, Department of Gastroenterology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Fang
F
Guo
Fang Guo, Yu-Fen Zhou, Fan Zhang, Yao-Zong Yuan, Wei-Yan Yao, Department of Gastroenterology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Yu-Fen
YF
Zhou
Fang Guo, Yu-Fen Zhou, Fan Zhang, Yao-Zong Yuan, Wei-Yan Yao, Department of Gastroenterology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Fan
F
Zhang
Fang Guo, Yu-Fen Zhou, Fan Zhang, Yao-Zong Yuan, Wei-Yan Yao, Department of Gastroenterology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Fei
F
Yuan
Fang Guo, Yu-Fen Zhou, Fan Zhang, Yao-Zong Yuan, Wei-Yan Yao, Department of Gastroenterology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Yao-Zong
YZ
Yuan
Fang Guo, Yu-Fen Zhou, Fan Zhang, Yao-Zong Yuan, Wei-Yan Yao, Department of Gastroenterology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Wei-Yan
WY
Yao
D003113:Colonoscopy; D004365:Drugs, Chinese Herbal / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008643:Mesentery / Q000098:blood supply*; D008875:Middle Aged; D010690:Phlebography / Q000379:methods; D011237:Predictive Value of Tests; D012307:Risk Factors; D012598:Sclerosis; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D061205:Vascular Calcification / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D014680:Veins / Q000187:drug effects / Q000473:pathology
D004365:Drugs, Chinese Herbal
Chinese medical liquor; Colonoscopy; Computed tomography enterography; Idiopathic mesenteric phlebosclerosis; Ileus