The dark side of DNA repair.
The BER pathway is widely used to repair DNA damage in cells, but it can also introduce unwanted mutations and is sometimes hijacked by other pathways.
Samuel H Wilson is in the Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, United States wilson5@niehs.nih.gov.
Samuel H
SH
Wilson
D020137:Base Pair Mismatch; D004247:DNA / Q000235:genetics*; D004260:DNA Repair; D006801:Humans; D009154:Mutation
D004247:DNA
APOBEC deaminase; DNA repair; mutagenesis; mutations