A novel phenolic acid from the fruits of Rosa soulieana.
From the n-BuOH-soluble fraction of a MeOH extract of the fruits of Rosa soulieana, one new phenolic glucoside (1) was isolated along with five known compounds, comprising two lignin glycosides, two flavonoid glycosides and a phenolic glycoside. The chemical structure of the new compound was elucidated by extensive spectroscopic analyses, including ESI-MS, UV, IR, (1)H and (13)C NMR, DEPT and 2D NMR (HSQC and HMBC). All the isolated compounds were evaluated for their antioxidant activity by using ABTS (2,2'-azino-bis(3-ethylbenzoline-6-sulfonic acid)) assay. Among these compounds, 1, 3 and 6 exhibited strong scavenging activity in ABTS(·+)(SC50 = 102.10, 193.85, 65.38 μmol/L, respectively) compared with the positive control l-ascorbic acid (Vc) (SC50 = 117.16 μmol/L).
a Chengdu Institute of Biology, Chinese Academy of Sciences , Chengdu 610041 , P.R. China.
Wenjun
W
He
Chunyan
C
Yang
Mingkui
M
Wang
Fu
F
Li
D001205:Ascorbic Acid / Q000494:pharmacology; D052160:Benzothiazoles / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005638:Fruit / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D062385:Hydroxybenzoates / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D027826:Rosa / Q000737:chemistry*; D013451:Sulfonic Acids / Q000494:pharmacology
D052160:Benzothiazoles; D004365:Drugs, Chinese Herbal; D006027:Glycosides; D062385:Hydroxybenzoates; D013451:Sulfonic Acids; C000592946:soulieana acid; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; C017616:phenolic acid; D001205:Ascorbic Acid
ABTS; Rosa soulieana; antioxidative; phenolic glucoside