Outcomes following Boston type 1 keratoprosthesis implantation in aniridia patients at the University of Montreal.
OBJECTIVE
To describe outcomes after Boston Type 1 Keratoprosthesis (KPro) surgery in aniridic eyes.


METHODS
Retrospective, interventional case series.


METHODS



METHODS
University-based tertiary care institution.


METHODS
Twenty-six aniridic eyes of 19 patients who underwent KPro implantation by a single experienced surgeon (M.H.-D.) between October 27, 2008 and January 16, 2012.


METHODS
Preoperative and postoperative best-corrected visual acuity (BCVA), intraoperative and postoperative complications, and keratoprosthesis retention.


RESULTS
Mean age was 56 years (range, 28-72); 10 patients were male. Seven patients had bilateral procedures. No intraoperative complications were encountered. Preoperatively, BCVA was 20/300 or worse in all eyes. After a mean follow-up time of 28.7±13.5 months (range 4-50), the most recent BCVA was 20/200 or better in 14 eyes. Visual potential was limited by preexisting terminal glaucoma (n=2), phthisis after retinal detachment (n=4), and suprachoroidal hemorrhage (n=2). Other postoperative complications included retroprosthetic membrane formation (n=15), infectious keratitis (n=1), extrusion (n=2), and corneal melt (n=4). Uncomplicated vitritis was reported in 6 eyes. No endophthalmitis occurred in this series. Most eyes have glaucoma and are on medical treatment. The overall retention rate of the initial prosthesis was 77%.


CONCLUSIONS
The prognosis in aniridic patients after KPro is variable. Meticulous follow-up and a subspecialty team approach are of utmost importance.
Department of Ophthalmology, Centre Hospitalier de l'Université de Montréal - Hôpital Notre-Dame, Montreal, Quebec, Canada. Electronic address: salima.hassanaly@gmail.com.
Salima I
SI
Hassanaly
Department of Ophthalmology, Centre Hospitalier de l'Université de Montréal - Hôpital Notre-Dame, Montreal, Quebec, Canada.
Julia C
JC
Talajic
Department of Ophthalmology, Centre Hospitalier de l'Université de Montréal - Hôpital Notre-Dame, Montreal, Quebec, Canada.
Mona
M
Harissi-Dagher
D000328:Adult; D000368:Aged; D015783:Aniridia / Q000601:surgery*; D001187:Artificial Organs; D003315:Cornea; D005260:Female; D005500:Follow-Up Studies; D006785:Hospitals, University; D006801:Humans; D008297:Male; D008875:Middle Aged; D019736:Prostheses and Implants; D011474:Prosthesis Design; D011792:Quebec; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D014792:Visual Acuity