The application of capillary electrophoresis techniques in toxicological analysis.
Capillary electrophoresis (CE) comprises a group of techniques used to separate chemical mixtures. Analytical separation is based on different electrophoretic mobilities, thereby allowing qualitative and quantitative evaluations to be made. The application of CE in medical science, especially in toxicological studies, is developing rapidly because of the short time required for analysis and its high sensitivity, selectivity and ability to determine substances of an acidic, alkaline and neutral character. This review focuses on the possibility of applying CE in toxicological analysis. Advances in different CE analyses and detection techniques connected with this method are described.
Department of Biomedical and Environmental Analysis, Faculty of Pharmacy, Wroclaw Medical University, Poland.
Ewelina
E
Sieradzka
Katarzyna
K
Witt
Halina
H
Milnerowicz
D019075:Electrophoresis, Capillary / Q000379:methods*; D014116:Toxicology / Q000379:methods*
capillary electrophoresis; drug; overdose; poisoning; toxicological analysis