Effect of intraoperative heparin administration on some indices of the blood coagulatory-lytic system in the ischemic region of the small intestine with anastomosis.
Several parameters of blood coagulation-lytic system were estimated in an ischemic region of narrow intestine with anastomosis in absence of heparin therapy and after subcutaneous intraoperative heparin administration. Single heparin injection in high therapeutic doses (200 U/kg body weight) during the fi nal stage of surgery prevents not only thrombosis of mesenteric blood vessels, but to a certain extent intraperitoneal adhesions.
N. P. Ogarev Mordovia State University, Saransk, Russia, markosyansa@mail.ru.
S A
SA
Markos'yan
N M
NM
Lysyakov
M A
MA
Ismail Alawal
K I
KI
Irkova
I V
IV
Martyanov
D000714:Anastomosis, Surgical / Q000009:adverse effects*; D000818:Animals; D000925:Anticoagulants / Q000627:therapeutic use*; D001777:Blood Coagulation / Q000187:drug effects; D004285:Dogs; D006493:Heparin / Q000627:therapeutic use*; D007082:Ileum / Q000098:blood supply* / Q000601:surgery; D007415:Intestinal Obstruction / Q000188:drug therapy / Q000517:prevention & control; D010529:Peritoneal Cavity / Q000473:pathology; D010538:Peritonitis / Q000188:drug therapy / Q000517:prevention & control; D000267:Tissue Adhesions / Q000188:drug therapy / Q000517:prevention & control*; D020246:Venous Thrombosis / Q000188:drug therapy / Q000517:prevention & control
D000925:Anticoagulants; D006493:Heparin