Omentin, fat and heart: classical music with new instruments.
Obesity is a new pandemic and its cardiovascular and metabolic complications will be more evident in the near future. The need to elucidate the structure and function of adipose tissue is becoming more prominent. Body fat mass has long become not just a matter of quantification, but an area of great interest due to the paracrine, endocrine and autocrine properties of its elements. The novel adipokines are under intense investigation and omentin has come into the centre of interest due to its favourable effects on inflammation and glucose homeostasis. Not all aspects of omentin have been clarified. This review tries to focus on the current knowledge of these aspects and the future perspectives of this novel adipokine.
Hippokration Hospital, Cardiology Department, Athens, Greece.
Vasiliki
V
Katsi
Attikon Hospital, 2(nd) University Cardiology Department, Athens, Greece. Electronic address: gvamva@yahoo.gr.
Georgia
G
Vamvakou
Attikon Hospital, 2(nd) University Cardiology Department, Athens, Greece.
John
J
Lekakis
Hippokration Hospital, 1(st) University Cardiology Department, Athens, Greece.
Dimitris
D
Tousoulis
Hippokration Hospital, 1(st) University Cardiology Department, Athens, Greece.
Christodoulos
C
Stefanadis
Helena Venizelou Maternity and General Hospital, Cardiology Department, Greece.
Thomas
T
Makris
Hippokration Hospital, Cardiology Department, Athens, Greece.
Ioannis
I
Kallikazaros
D054392:Adipokines / Q000097:blood; D052436:Adipose Tissue, White / Q000378:metabolism; D000818:Animals; D003324:Coronary Artery Disease / Q000097:blood; D016207:Cytokines / Q000097:blood*; D003920:Diabetes Mellitus / Q000097:blood*; D004727:Endothelium; D058851:GPI-Linked Proteins / Q000097:blood; D006801:Humans; D007333:Insulin Resistance; D037102:Lectins / Q000097:blood*; D024821:Metabolic Syndrome / Q000097:blood*; D009765:Obesity / Q000097:blood*
D054392:Adipokines; D016207:Cytokines; D058851:GPI-Linked Proteins; C432397:ITLN1 protein, human; D037102:Lectins; C000591992:omentin protein, rat
Cardiovascular effects; Inflammation; Insulin resistance; Novel adipokines; Obesity; Omentin