CuI catalyzed sulfonylation of organozinc reagents with sulfonyl halides.
In this study, a facile CuI catalyzed synthesis of sulfones involving a nucleophilic addition of functionalized organozinc reagents to organic sulfonyl chlorides is realized. This reaction proceeds efficiently at room temperature, giving rise to various functional group substituted sulfones, generally in moderate to high yields. The method provides a novel, simple, and promising strategy for functionalized sulfone synthesis in the research field of sulfur chemistry.
College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, Gansu 730070, PR China. fuying@iccas.ac.cn.
Ying
Y
Fu
Wenbo
W
Zhu
Xingling
X
Zhao
Helmut
H
Hügel
Zhouqiang
Z
Wu
Yuhu
Y
Su
Zhengyin
Z
Du
Danfeng
D
Huang
Yulai
Y
Hu
D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006219:Halogens / Q000737:chemistry*; D007454:Iodides / Q000737:chemistry*; D009930:Organic Chemicals / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry; D013450:Sulfones / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
D006219:Halogens; D007454:Iodides; D009930:Organic Chemicals; D013450:Sulfones; D003300:Copper; C073870:cuprous iodide; D015032:Zinc; D010100:Oxygen