Avatar DNA nanohybrid system in chip-on-a-phone.
Long admired for informational role and recognition function in multidisciplinary science, DNA nanohybrids have been emerging as ideal materials for molecular nanotechnology and genetic information code. Here, we designed an optical machine-readable DNA icon on microarray, Avatar DNA, for automatic identification and data capture such as Quick Response and ColorZip codes. Avatar icon is made of telepathic DNA-DNA hybrids inscribed on chips, which can be identified by camera of smartphone with application software. Information encoded in base-sequences can be accessed by connecting an off-line icon to an on-line web-server network to provide message, index, or URL from database library. Avatar DNA is then converged with nano-bio-info-cogno science: each building block stands for inorganic nanosheets, nucleotides, digits, and pixels. This convergence could address item-level identification that strengthens supply-chain security for drug counterfeits. It can, therefore, provide molecular-level vision through mobile network to coordinate and integrate data management channels for visual detection and recording.
1] Center for Intelligent NanoBio Materials (CINBM), Department of Chemistry and Nano Science (Ewha Global Top 5 program-2011) and Department of Bioinspired Science, Ewha Womans University, Seoul 120-750, Republic of Korea [2] Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul 120-749, Republic of Korea.
Dae-Hwan
DH
Park
Center for Intelligent NanoBio Materials (CINBM), Department of Chemistry and Nano Science (Ewha Global Top 5 program-2011) and Department of Bioinspired Science, Ewha Womans University, Seoul 120-750, Republic of Korea.
Chang Jo
CJ
Han
Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul 120-749, Republic of Korea.
Yong-Gun
YG
Shul
Center for Intelligent NanoBio Materials (CINBM), Department of Chemistry and Nano Science (Ewha Global Top 5 program-2011) and Department of Bioinspired Science, Ewha Womans University, Seoul 120-750, Republic of Korea.
Jin-Ho
JH
Choy
D004247:DNA / Q000737:chemistry*; D046228:Microarray Analysis / Q000379:methods*; D036103:Nanotechnology / Q000379:methods*; D012984:Software
D004247:DNA