Adverse cardiovascular effects from the use of anabolic-androgenic steroids as ergogenic resources.
This review evaluates the documented cardiovascular functioning among anabolic-androgenic steroid (AAS) users. AAS users manifest a reduction in HDL cholesterol, increased inflammatory markers, and oxidative stress. Strong evidence associating AAS use with blood pressure at hypertensive levels, as well as hypertrophy and cardiac dysfunction has also been reported. Both epidemiological and autopsy studies attest the relationship between AAS use and early mortality. The review's limitations are noted.
1Departamento de Biofísica e Fisiologia, Campus Universitário Ministro Petrônio Portella, Universidade Federal do Piauí , Teresina-PI , Brasil.
Marcos Antonio Pereira dos
MA
Santos
Caio Victor Coutinho de
CV
Oliveira
Alexandre Sérgio
AS
Silva
D045930:Anabolic Agents / Q000009:adverse effects*; D000728:Androgens / Q000009:adverse effects*; D020520:Brain Infarction / Q000175:diagnosis*; D002318:Cardiovascular Diseases / Q000139:chemically induced*; D004300:Doping in Sports; D050171:Dyslipidemias / Q000139:chemically induced*; D006801:Humans
D045930:Anabolic Agents; D000728:Androgens
anabolic agents; cardiac hypertrophy; cardiovascular diseases; doping in sports; hypertension