Parallel acquisition of q-space using second order magnetic fields for single-shot diffusion measurements.
A proof of concept is presented for the parallel acquisition of q-space under diffusion using a second order magnetic field. The second order field produces a gradient strength which varies in space, allowing a range of gradients to be applied in a single pulse, and q-space encoded into real space. With the use of a read gradient, the spatial information is regained from the NMR signal, and real space mapped onto q-space for a thin slice excitation volume. As the diffusion encoded image for a thin slice can be mapped onto q-space, and the average propagator is the inverse Fourier transform of the q-space data, it follows that the acquisition of the echo is a direct measurement of the average propagator. In the absence of a thin slice selection, the real space to q-space mapping is lost, but the ability to measure the diffusion coefficient retained with an increase in signal to noise.
MacDiarmid Institute for Advanced Materials and Nanotechnology, School of Chemical and Physical Sciences, Victoria University of Wellington, PO Box, 600, 6140 Wellington, New Zealand. Electronic address: wilfred.kittler@vuw.ac.nz.
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Kittler
MacDiarmid Institute for Advanced Materials and Nanotechnology, School of Chemical and Physical Sciences, Victoria University of Wellington, PO Box, 600, 6140 Wellington, New Zealand. Electronic address: petrik.galvosas@vuw.ac.nz.
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Galvosas
MacDiarmid Institute for Advanced Materials and Nanotechnology, School of Chemical and Physical Sciences, Victoria University of Wellington, PO Box, 600, 6140 Wellington, New Zealand; Magritek Ltd., 32 Salamanca Rd., 6012 Wellington, New Zealand. Electronic address: mark.hunter@vuw.ac.nz.
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Hunter
Diffusion; PGSE; Parabolic; Parallel; Second order; Single-shot; q-space