Advances in geroscience: impact on healthspan and chronic disease.
Population aging is unprecedented, without parallel in human history, and the 21st century will witness even more rapid aging than did the century just past. Improvements in public health and medicine are having a profound effect on population demographics worldwide. By 2017, there will be more people over the age of 65 than under age 5, and by 2050, two billion of the estimated nine billion people on Earth will be older than 60 (http://unfpa.org/ageingreport/). Although we can reasonably expect to live longer today than past generations did, the age-related disease burden we will have to confront has not changed. With the proportion of older people among the global population being now higher than at any time in history and still expanding, maintaining health into old age (or healthspan) has become a new and urgent frontier for modern medicine. Geroscience is a cross-disciplinary field focused on understanding the relationships between the processes of aging and age-related chronic diseases. On October 30-31, 2013, the trans-National Institutes of Health GeroScience Interest Group hosted a Summit to promote collaborations between the aging and chronic disease research communities with the goal of developing innovative strategies to improve healthspan and reduce the burden of chronic disease.
Center for Scientific Review, National Institutes of Health, Bethesda, Maryland.
John B
JB
Burch
Immunoregulation Section, Basic Immunology Branch, Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland.
Alison Deckhut
AD
Augustine
Research Training and Career Development Branch, National Institute of Dental and Craniofacial Research, Bethesda, Maryland.
Leslie A
LA
Frieden
Division of Geriatrics and Clinical Gerontology, National Institute on Aging, Bethesda, Maryland.
Evan
E
Hadley
National Cancer Institute, NIH, Division of Cancer Biology, Bethesda, Maryland.
T Kevin
TK
Howcroft
Cancer Etiology Branch, DNA and Chromosome Aberrations Branch, Division of Cancer Biology, National Cancer Institute, Bethesda, Maryland.
Ron
R
Johnson
Division of Extramural Research, National Center for Complementary and Alternative Medicine, Bethesda, Maryland.
Partap S
PS
Khalsa
Division of Aging Biology, National Institute on Aging, Bethesda, Maryland. kohanskir@mail.nih.gov.
Ronald A
RA
Kohanski
Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.
Xiao Ling
XL
Li
Radiation and Nuclear Countermeasures, Program Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland.
Francesca
F
Macchiarini
Geriatrics and Aging Processes Research Branch, National Institute of Mental Health, Bethesda, Maryland.
George
G
Niederehe
Vascular Biology and Hypertension Branch, Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland.
Young S
YS
Oh
Pharmacogenomics and Drug Discovery, National Institute of Diabetes and Digestive and Kidney Diseases, Division of Diabetes, Endocrinology, and Metabolic Diseases, Bethesda, Maryland.
Aaron C
AC
Pawlyk
Office of Cancer Clinical Proteomics Research, Office of the Director and.
Henry
H
Rodriguez
Office of Cancer Survivorship, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland.
Julia H
JH
Rowland
Retinal Diseases Program, Division of Extramural Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland.
Grace L
GL
Shen
Division of Aging Biology and.
Felipe
F
Sierra
Neurobiology of Aging Branch, Division of Neuroscience, National Institute on Aging, Bethesda, Maryland.
Bradley C
BC
Wise
D000375:Aging; D035843:Biomedical Research / Q000639:trends*; D002908:Chronic Disease / Q000453:epidemiology*; D003226:Congresses as Topic; D005853:Geriatrics / Q000379:methods*; D014943:Global Health; D006801:Humans; D008017:Life Expectancy / Q000639:trends*; D009017:Morbidity / Q000639:trends
Chronic disease; Geroscience.