Telechelic Poly(disulfide)s and Related Block Copolymer.
In this communication, a mild, efficient, and generalized polycondensation route is developed for poly(disulfide)s from commercially available monomers 2,2'-dithiodipyridine and 1,6-hexanedithiol. Using the stoichiometric imbalance between the two monomers, it is possible to produce telechelic poly(disulfide)s of predictable molecular weight with reactive pyridyl disulfide groups at both the terminals of the chain. The two terminal pyridyl disulfide groups can be quantitatively replaced by a functional thiol using selective thiol-disulfide exchange and thus produces functional telechelic poly(disulfide)s, which can be used as a macroinitiator to initiate ring-opening poly-merization of a cyclic lactide monomer generating an ABA-type triblock copolymer with degradable B block.
Polymer Science Unit, Indian Association for the Cultivation of Science, 2A & 2B Raja S. C. Mullick Road, Kolkata, 700032, India.
Dipankar
D
Basak
Rajan
R
Kumar
Suhrit
S
Ghosh
D015082:2,2'-Dipyridyl / Q000031:analogs & derivatives / Q000737:chemistry; D004146:Dioxanes / Q000737:chemistry; D004220:Disulfides / Q000737:chemistry; D008970:Molecular Weight; D058105:Polymerization; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D013438:Sulfhydryl Compounds / Q000737:chemistry
D004146:Dioxanes; D004220:Disulfides; D011108:Polymers; D013438:Sulfhydryl Compounds; C001105:2,2'-dipyridyl disulfide; D015082:2,2'-Dipyridyl; C091880:dilactide; C501433:1,6-hexanedithiol
block copolymer; condensation reaction; poly(disulfide)s; ring-opening polymerization; stoichiometric imbalance