2-Ethyl-3-[(R)-2-phenyl-butanamido]-quinazolin-4(3H)-one monohydrate.
In the title compound, C20H21N3O2·H2O (EQR·H2O), the quinazoline ring system forms dihedral angles of 53.1 (1) and 85.6 (1)° with the phenyl ring and the amide link, respectively. In the crystal, O-H⋯O hydrogen bonds link two EQR and two water mol-ecules into a centrosymmetric R 4 (4)(18) ring motif. N-H⋯O hydrogen bonds further link these hydrogen-bonded fragments into columns extending in [010].
Cornea Research Chair, Department of Optometry, College of Applied Medical Sciences, King Saud University, PO Box 10219, Riyadh 11433, Saudi Arabia.
Gamal A
GA
El-Hiti
School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, Wales.
Keith
K
Smith
School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, Wales.
Amany S
AS
Hegazy
School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, Wales.
D Heulyn
DH
Jones
School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, Wales.
Benson M
BM
Kariuki