Canine low-grade intra-orbital myxosarcoma: case report.
OBJECTIVE
The aim of this study was to evaluate important clinical, morphological, histopathological, histochemical, and immunohistochemical characteristics in order to establish the diagnosis and prognosis of a low-grade intra-orbital myxosarcoma.


METHODS
A mongrel dog presented a 2-year history of a neoplastic mass behind the right eye.


RESULTS
The neoplasm presented a mesenchymal spindle and stellate cell proliferation with an abundant myxoid matrix, moderate anisocariosis, and a low mitotic index. It stained positive for vimentin, moderately positive for periodic acid-Schiff, and negative for Gomori trichrome stain and α-smooth muscle actin.


CONCLUSIONS
One year following surgical excision, the patient remains disease free. The histological findings established a diagnosis of a rare canine intra-orbital low-grade myxosarcoma.
Laboratory of Comparative Pathology, Department of General Pathology, Biological Science Institute, Federal University of Minas Gerais (UFMG), Belo Horizonte, MG, 31270-901, Brazil.
Cecília B
CB
Campos
Fernanda C
FC
Nunes
Conrado O
CO
Gamba
Karine A
KA
Damasceno
Cristina M
CM
Souza
Liliane C
LC
Campos
Geovanni D
GD
Cassali
D000818:Animals; D004283:Dog Diseases / Q000473:pathology* / Q000601:surgery; D004285:Dogs; D005134:Eye Neoplasms / Q000473:pathology* / Q000601:surgery; D009236:Myxosarcoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary*
dog; myxosarcoma; neoplasm; orbital