[A woman with complaints after an injection of diclofenac].
A 61-year-old woman came to the Emergency Department with a skin lesion located at her right upper leg. At the site of the lesion a subcutaneous injection of diclofenac had been administered for pain from nephrolithiasis. CT revealed a large infiltrate proximal in the right upper leg; histologic evaluation of the tissue showed an acute necrotizing inflammation. These findings are typical for Nicolau syndrome.
Rijnland Ziekenhuis, Leiderdorp.
Jan-Willem  H J
JW
Geerts
Andrea M
AM
Siegel
Anne
A
Bosman
D004008:Diclofenac / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular / Q000009:adverse effects*; D007866:Leg; D008875:Middle Aged; D065148:Nicolau Syndrome / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery
D004008:Diclofenac