Cerebral ischemic involvement in Vogt-Koyanagi-Harada disease.
BACKGROUND
Vogt-Koyanagi-Harada (VKH) disease is an autoimmune disorder characterized by ocular, auditory and neurological manifestations (headache, meningismus and/or aspeptic meningoencephalitis).


METHODS
We describe a 12-year-old African boy with bilateral uveitis who presented with acute unilateral hearing loss and neurological symptoms such as left-sided dyskinesias, unsteady gait and throbbing headache. Brain magnetic resonance imaging showed ischemic lesions of the right basal ganglia in the territory of lenticulostriate and thalamic arteries. He improved after treatment with intravenous and oral steroids.


CONCLUSIONS
Cerebral ischemic episodes should be included in the possible neurological manifestations of VKH.
Child Neuropsychiatry Unit, Department of Pediatrics, S.Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy. Electronic address: r.vergaro@gmail.com.
Raffaella
R
Vergaro
Child Neuropsychiatry Unit, Department of Pediatrics, S.Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Duccio Maria
DM
Cordelli
Department of Pediatrics, S.Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Angela
A
Miniaci
Department of Pediatrics, S.Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Davide
D
Tassinari
Neuroradiology Unit, S.Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Luca
L
Spinardi
Department of Pediatrics, S.Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Andrea
A
Pession
Child Neuropsychiatry Unit, Department of Pediatrics, S.Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Emilio
E
Franzoni
D015901:Angiography, Digital Subtraction; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D002545:Brain Ischemia / Q000150:complications*; D002648:Child; D006801:Humans; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D014607:Uveomeningoencephalitic Syndrome / Q000175:diagnosis / Q000209:etiology*
Vogt-Koyanagi-Harada disease; autoimmune; children; neurological manifestations; panuveitis