Prevalence of developmental odontogenic cysts in children and adolescents with emphasis on dentigerous cyst and odontogenic keratocyst (keratocystic odontogenic tumor).
OBJECTIVE
To investigate the incidence and prevalence of developmental odontogenic cysts in children and adolescents and compare the features of the two most common types, dentigerous cyst and keratocystic odontogenic tumor (KCOT).


METHODS
A retrospective review in a series of 369 patients with all histological diagnoses of developmental odontogenic cysts in children (≤12 years) and adolescents (13-18 years) was conducted.


RESULTS
Among these, 361 (97.8%) patients were diagnosed as dentigerous cyst (n = 281) and KCOT (n = 80), with the male-to-female ratios of dentigerous cyst and KCOT both being 2:1. The average age of the patients with KCOT was older than that of those with dentigerous cyst (14.7 years vs 11.8 years, p < 0.001). Dentigerous cyst (59.1%) was more common in children, but KCOT (78.8%) was more common in adolescents (p < 0.001). Dentigerous cyst (57.6%) predominantly located on the maxilla, but KCOT (60.3%) predominantly located on the mandible (p = 0.010).


CONCLUSIONS
Adolescent patients with lesions located on the mandible would favor KCOT over dentigerous cyst. This study aids in better knowledge of the prevalence of developmental odontogenic cysts in a large pediatric population, and shows that a well-supported early diagnosis is indispensable for a more adequate treatment.
School of Stomatology, Jilin University , Changchun, Jilin , China.
Nannan
N
Li
Xing
X
Gao
Ziyuan
Z
Xu
Zhuo
Z
Chen
Laikuan
L
Zhu
Jinrui
J
Wang
Wei
W
Liu
D000293:Adolescent; D000367:Age Factors; D002648:Child; D002681:China / Q000453:epidemiology; D003803:Dentigerous Cyst / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000453:epidemiology; D008339:Mandibular Neoplasms / Q000453:epidemiology; D008439:Maxillary Diseases / Q000453:epidemiology; D008441:Maxillary Neoplasms / Q000453:epidemiology; D009807:Odontogenic Cysts / Q000453:epidemiology*; D009808:Odontogenic Tumors / Q000453:epidemiology*; D015995:Prevalence; D012189:Retrospective Studies; D012737:Sex Factors
dentigerous cyst; developmental odontogenic cysts; keratocystic odontogenic tumor; pediatrics