Human papillomavirus-related cancers among people living with AIDS in Puerto Rico.
The objective of this study was to estimate the incidence of cancer and human papillomavirus (HPV)-related cancers and the risk of death (by cancer status) among people living with AIDS (PLWA) in Puerto Rico. We used data from the Puerto Rico AIDS Surveillance Program and Central Cancer Registry (1985-2005). Cancers with highest incidence were cervix (299.6/100,000) for women and oral cavity/oropharynx for men (150.0/100,000); the greatest excess of cancer incidence for men (standardized incidence ratio, 86.8) and women (standardized incidence ratio, 52.8) was for anal cancer. PLWA who developed a cancer had decreased survival and increased risk of death compared with those who did not have cancer. Cancer control strategies for PLWA will be essential for improving their disease survival.
University of Puerto Rico Comprehensive Cancer Center and Graduate School of Public Health, University of Puerto Rico, PMB 711, 89 De Diego Ave, Suite 105, San Juan, PR 00927-6346. Telephone: 787-772-8300, Ext 1204. E-mail: ana.ortiz7@upr.edu.
Ana Patricia
AP
Ortiz
University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico.
Javier
J
Pérez-Irizarry
University of Puerto Rico, San Juan, Puerto Rico.
Marievelisse
M
Soto-Salgado
University of Puerto Rico, San Juan, Puerto Rico.
Erick
E
Suárez
University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico.
Naydi
N
Pérez
Puerto Rico Department of Health, HIV Surveillance Program, San Juan, Puerto Rico.
Maritza
M
Cruz
University of California, San Francisco, San Francisco, California.
Joel
J
Palefsky
University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico.
Guillermo
G
Tortolero-Luna
Puerto Rico Department of Health, HIV Surveillance Program, San Juan, Puerto Rico.
Sandra
S
Miranda
University of Puerto Rico, San Juan, Puerto Rico.
Vivian
V
Colón-López
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D000293:Adolescent; D000328:Adult; D015897:Comorbidity; D017281:Cost of Illness; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology* / Q000209:etiology / Q000821:virology*; D030361:Papillomavirus Infections / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D011647:Puerto Rico / Q000453:epidemiology; D011788:Quality of Life; D012042:Registries / Q000706:statistics & numerical data; D012307:Risk Factors; D018571:Sentinel Surveillance; D012737:Sex Factors; D011795:Surveys and Questionnaires; D016019:Survival Analysis; D055815:Young Adult