Antimicrobial prophylaxis in hematopoietic stem cell transplantation recipients: 10 years after.
BACKGROUND
Antimicrobial prophylaxis is recommended for all patients undergoing hematopoietic stem cell transplantation. Evidence-based guidelines recently have been updated to incorporate the results from recent clinical studies.


METHODS
An antimicrobial prophylaxis survey was conducted during the 2013 ASBMT Tandem Meetings to discern the degree of concordance between transplant centers and society guidelines.


RESULTS
The results show significant differences in prescribing practices among transplant institutions and variance with evidence-based guidelines.


CONCLUSIONS
The clinical significance of this discordance is unknown.
Department of Hematology and Oncology, Robert Lurie Cancer Center and Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
S
S
Trifilio
J
J
Mehta
D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D000998:Antiviral Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000517:prevention & control; D003625:Data Collection; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D009181:Mycoses / Q000517:prevention & control; D010818:Practice Patterns, Physicians' / Q000592:standards*; D014777:Virus Diseases / Q000517:prevention & control
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D000998:Antiviral Agents
antimicrobial prophylaxis; guidelines; infection; stem cell transplantation; survey