A symmetric pseudo salen based turn-on fluorescent probe for sensitive detection and visual analysis of zinc ion.
A turn-on fluorescence probe for zinc ion has been synthesized, which contains a symmetric pseudo salen moiety as zinc recognition site. The multidentate salen ligand chelates with zinc ions, and generates the rigidity of the zinc complex, which subsequently results in a dramatic fluorescence enhancement of the probe. Mass spectral and spectroscopic results reveal that the reaction proceeds rapidly in a 1 to 1 stoichiometric manner to form a clean zinc complex. We have demonstrated that the fluorescence probe not only has high selectivity for zinc ion over other biological relevant ions but also shows high sensitivity for zinc ion with a detection limit of 83 nM. A fluorescence test paper has been developed by incorporating the probe on a polyamide fiber paper. The fluorescence color of the test paper became bright green-yellow under UV lamp when water sample containing zinc ions was dropped on it, suggesting its potential application in the measurement of zinc ions.
Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei 230031, PR China.
Huan
H
Yu
Beijing Institute of Pharmaceutical Chemistry, State Key Laboratory of NBC Protection for Civilian, Beijing 102205, PR China.
Tao
T
Yu
Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei 230031, PR China.
Mingtai
M
Sun
Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei 230031, PR China; Department of Chemistry, University of Science & Technology of China, Hefei 230026, PR China.
Jian
J
Sun
Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei 230031, PR China; Department of Chemistry, University of Science & Technology of China, Hefei 230026, PR China.
Shan
S
Zhang
Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei 230031, PR China; Department of Chemistry, University of Science & Technology of China, Hefei 230026, PR China. Electronic address: shwang@iim.ac.cn.
Suhua
S
Wang
Beijing Institute of Pharmaceutical Chemistry, State Key Laboratory of NBC Protection for Civilian, Beijing 102205, PR China. Electronic address: jiangtide@sina.cn.
Hui
H
Jiang
D001665:Binding Sites; D002614:Chelating Agents; D005029:Ethylenediamines / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D007477:Ions; D008024:Ligands; D013058:Mass Spectrometry; D008422:Materials Testing; D015394:Molecular Structure; D010777:Photochemistry; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet; D015032:Zinc / Q000737:chemistry*
D002614:Chelating Agents; D005029:Ethylenediamines; D005456:Fluorescent Dyes; D007477:Ions; D008024:Ligands; C011452:disalicylaldehyde ethylenediamine; D015032:Zinc
Coordination modes; Fluorescent probes; Pseudo salen moiety; Visual detection; Zinc ion