A rare glutamine derivative from the flower buds of daylily.
A rare glutamine derivative, hemerocallisamine I (1), was isolated from the methanolic extract of the flower buds of daylily, together with a new pyrrole alkaloid hemerocallisamine II (2) and a new γ-lactam derivative, hemerocallisamine III (3). The chemical structures of the new compounds were elucidated on the basis of chemical and physicochemical evidence. For hemerocallisamine I (1), the absolute configuration was determined by Mo-Kα X-ray crystallographic analysis. This is the first report of a glutamine derivative with a pyrrole ring from natural plants.
Kyoto Pharmaceutical University , Misasagi, Yamashina-ku, Kyoto 607-8412, Japan.
Takahiro
T
Matsumoto
Seikou
S
Nakamura
Tomoe
T
Ohta
Katsuyoshi
K
Fujimoto
Masayuki
M
Yoshikawa
Keiko
K
Ogawa
Hisashi
H
Matsuda
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D035264:Flowers; D005973:Glutamine / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000302:isolation & purification; D007769:Lactams / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011758:Pyrroles / Q000737:chemistry* / Q000302:isolation & purification
D000470:Alkaloids; D007769:Lactams; D011758:Pyrroles; C000592092:hemerocallisamine I; C000591962:hemerocallisamine II; C000591963:hemerocallisamine III; D005973:Glutamine