title: Successful surgical treatment of extrahepatic biliary papillomatosis diagnosed with endoscopic retrograde cholangiopancreatography: a case report.
abstract: BACKGROUND
  Biliary papillomatosis is a condition characterized by multiple papillary tumors of variable distribution and extent within the biliary tract. Papillary carcinoma can develop in these lesions. It is a rare biliary pathological entity and its clinical features and outcome are not well known.
  
  
  METHODS
  We experienced a case of biliary papillomatosis in a 51-year-old North African man who presented with obstructive jaundice. Laboratory tests showed elevated bilirubin, alkaline phosphatase and gamma-glutamyl transpeptidase levels. Imaging (ultrasound and magnetic resonance imaging) was suggestive of Klatskin tumor associated to common bile duct stones. After endoscopic retrograde cholangiopancreatography, a balloon sweep retrieved friable tissue from his bile ducts. Histology demonstrated papillary adenomatous proliferation showing high-grade dysplasia and he was referred for surgical management.
  
  
  CONCLUSIONS
  Although biliary papillomatosis is rare, it is a premalignant condition that should be well known and considered in all diagnoses of obstructive jaundice. We report a new case of biliary papillomatosis and highlight the contribution of endoscopic retrograde cholangiopancreatography in the diagnosis of this condition.
authors.affiliation: Department of Gastroenterology II, Mohamed V Teaching Military Hospital, Rabat 10100, Morocco. tarikadioui@gmail.com.
authors.forename: Tarik
authors.initials: T
authors.lastname: Adioui
authors.forename: Hassan
authors.initials: H
authors.lastname: Seddik
authors.forename: Hicham
authors.initials: H
authors.lastname: Baba
authors.forename: Badr
authors.initials: B
authors.lastname: Slioui
authors.forename: Abdelmounaim Ait
authors.initials: AA
authors.lastname: Ali
authors.forename: Fatima Zohra
authors.initials: FZ
authors.lastname: El Hamdi
authors.forename: Ahmed
authors.initials: A
authors.lastname: Benkirane
authors.forename: Aziz
authors.initials: A
authors.lastname: Zentar
mesh_terms: D001650:Bile Duct Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D017734:Bile Ducts, Extrahepatic / Q000601:surgery*; D002760:Cholangiopancreatography, Endoscopic Retrograde; D006801:Humans; D041781:Jaundice, Obstructive / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010212:Papilloma / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D016896:Treatment Outcome