title: Detectability of simulated interstitial pneumonia on chest radiographs: comparison between irradiation side sampling indirect flat-panel detector and computed radiography.
abstract: OBJECTIVE
  To compare the detectability of simulated interstitial pneumonia on chest radiographs between an irradiation side sampling indirect flat-panel detector (ISS-FPD) and computed radiography (CR).
  
  
  METHODS
  Simulated interstitial pneumonia findings (ground-glass opacity, reticular opacity and honeycomb lung) were superimposed on an anthropomorphic chest phantom. Chest radiographs were acquired under three exposure levels (4.0, 3.2 and 2.0 mAs) with an ISS-FPD and with CR. 5 thoracic radiologists evaluated 72 images for the presence or absence of a lesion over each of 6 areas. A total of 1296 observations were analysed in a receiver-operating characteristic analysis. A jackknife method was used for the statistical analysis.
  
  
  RESULTS
  The areas under the curves (AUCs) for the detection of simulated honeycomb lung obtained with the ISS-FPD were significantly larger than those obtained with CR at all exposure conditions. For the detection of simulated ground-glass opacity and reticular opacity, there were no significant differences between the two systems. In addition, the AUCs for the detectability of simulated honeycomb lung obtained with the ISS-FPD at all exposure levels were significantly larger than those obtained with CR at 4 mAs.
  
  
  CONCLUSIONS
  The ISS-FPD was superior to CR for the detection of simulated honeycomb lung. Provided that the chosen model is representative of interstitial pneumonia, the use of an ISS-FPD might reduce a patient's exposure dose during the detection of interstitial pneumonia.
  
  
  CONCLUSIONS
  The ISS-FPD has shown its advantage compared with CR in the detection of honeycombing, one sign of interstitial pneumonia.
authors.affiliation: 1 Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Yano
authors.forename: H
authors.initials: H
authors.lastname: Yabuuchi
authors.forename: A
authors.initials: A
authors.lastname: Kairada
authors.forename: N
authors.initials: N
authors.lastname: Tanaka
authors.forename: J
authors.initials: J
authors.lastname: Morishita
authors.forename: T
authors.initials: T
authors.lastname: Akasaka
authors.forename: Y
authors.initials: Y
authors.lastname: Matsuo
authors.forename: T
authors.initials: T
authors.lastname: Kamitani
authors.forename: Y
authors.initials: Y
authors.lastname: Yamasaki
authors.forename: M
authors.initials: M
authors.lastname: Nagao
authors.forename: M
authors.initials: M
authors.lastname: Sasaki
mesh_terms: D006801:Humans; D017563:Lung Diseases, Interstitial / Q000000981:diagnostic imaging*; D019047:Phantoms, Imaging; D013902:Radiography, Thoracic / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014963:X-Ray Intensifying Screens