title: Fluoride release, recharge and flexural properties of polymethylmethacrylate containing fluoridated glass fillers.
abstract: BACKGROUND
  The purpose of this study was to investigate the effect of fluoridated glass fillers on fluoride release, recharge and the flexural properties of modified polymethylmethacrylate (PMMA).
  
  
  METHODS
  Specimens of PMMA denture base material with various loading of fluoridated glass fillers (0%, 1%, 2.5%, 5% and 10% by weight) were prepared. Flexural properties were evaluated on rectangular specimens (n = 10) aged in deionized water after 24 hours, 1 and 3 months. Disc specimens (n = 10) were aged for 43 days in deionized water and lactic acid (pH 4.0) and fluoride release was measured at numerous intervals. After ageing, specimens were recharged and fluoride re-release was recorded at 1, 3 and 7 days after recharge.
  
  
  RESULTS
  Samples containing 2.5%, 5% and 10% glass fillers showed significantly (p < 0.05) greater levels of fluoride release compared with the control and 1% glass fillers specimens. All experimental specimens exhibited fluoride release in both media. The flexural strength of specimens decreased in proportion to the percentage filler inclusion with the modulus of elasticity values remaining within ISO Standard 1567.
  
  
  CONCLUSIONS
  The modified PMMA with fluoridated glass fillers has the ability to release and re-release fluoride ion. Flexural strength decreased as glass filler uploading increased.
authors.affiliation: Department of Biomaterials, Faculty of Dentistry, The University of Sydney, New South Wales, Australia.
authors.forename: I A
authors.initials: IA
authors.lastname: Al-Bakri
authors.forename: M V
authors.initials: MV
authors.lastname: Swain
authors.forename: S J
authors.initials: SJ
authors.lastname: Naoum
authors.forename: W M
authors.initials: WM
authors.lastname: Al-Omari
authors.forename: E
authors.initials: E
authors.lastname: Martin
authors.forename: A
authors.initials: A
authors.lastname: Ellakwa
mesh_terms: D000044:Dental Abutments / Q000009:adverse effects*; D003731:Dental Caries / Q000517:prevention & control*; D003819:Denture Bases; D004548:Elasticity; D005459:Fluorides / Q000008:administration & dosage*; D005898:Glass / Q000737:chemistry*; D005899:Glass Ionomer Cements / Q000737:chemistry; D008422:Materials Testing; D019904:Polymethyl Methacrylate / Q000737:chemistry*; D012969:Sodium Fluoride / Q000008:administration & dosage / Q000737:chemistry; D013997:Time Factors
chemical_list: D005899:Glass Ionomer Cements; D012969:Sodium Fluoride; D019904:Polymethyl Methacrylate; D005459:Fluorides
keywords: Flexural strength; fluoride release; glass fillers; modulus of elasticity; polymethylmethacrylate