title: In situ growth of silver nanoparticles on graphene quantum dots for ultrasensitive colorimetric detection of H₂O₂ and glucose.
abstract: We report a facile green approach for in situ growth of silver nanoparticles (AgNPs) on the surface of graphene quantum dots (GQDs). GQDs serve as both reducing agent and stabilizer, and no additional reducing agent and stabilizer is necessary. The GQDs/AgNPs hybrid exhibits a superior absorbance fading response toward the reduction of H2O2. A simple colorimetric procedure is thus proposed for ultrasensitive detection of H2O2 without additional chromogenic agent. It provides a record detection limit of 33 nM for the detection of H2O2 by the AgNPs-based sensing system. This colorimetric sensing system is further extended to the detection of glucose in combination with the specific catalytic effect of glucose oxidase for the oxidation of glucose and formation of H2O2, giving rise to a detection limit of 170 nM. The favorable performances of the GQDs/AgNPs hybrid are due to the peroxidase-like activity of GQDs.
authors.affiliation: Research Center for Analytical Sciences, Northeastern University , Box 332, Shenyang 110819, China.
authors.forename: Shuai
authors.initials: S
authors.lastname: Chen
authors.forename: Xin
authors.initials: X
authors.lastname: Hai
authors.forename: Xu-Wei
authors.initials: XW
authors.lastname: Chen
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Wang
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D003124:Colorimetry / Q000379:methods; D005947:Glucose / Q000032:analysis* / Q000378:metabolism; D005949:Glucose Oxidase / Q000378:metabolism; D006108:Graphite / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000032:analysis*; D057230:Limit of Detection; D053768:Metal Nanoparticles / Q000737:chemistry*; D045663:Quantum Dots / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*
chemical_list: D012834:Silver; D006108:Graphite; D006861:Hydrogen Peroxide; D005949:Glucose Oxidase; D005947:Glucose