title: Acetal-initiated Prins bicyclization for the synthesis of hexahydrofuro-[3,4-c]furan lignans and octahydropyrano[3,4-c]pyran derivatives.
abstract: An acetal-initiated Prins bicyclization approach has been developed for the stereoselective synthesis of hexahydrofuro[3,4-c]furan lignans. This also provides a direct way to generate a new series of octahydropyrano[3,4-c]pyran derivatives in a single-step process.
authors.affiliation: Natural Product Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad, India. basireddy@iict.res.in.
authors.forename: B V Subba
authors.initials: BV
authors.lastname: Reddy
authors.forename: M
authors.initials: M
authors.lastname: Ramana Reddy
authors.forename: B
authors.initials: B
authors.lastname: Sridhar
authors.forename: Kiran Kumar
authors.initials: KK
authors.lastname: Singarapu
mesh_terms: D000080:Acetals / Q000737:chemistry*; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D005663:Furans / Q000138:chemical synthesis / Q000737:chemistry; D017705:Lignans / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation; D011714:Pyrans / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000080:Acetals; D019086:Bridged Bicyclo Compounds, Heterocyclic; D005663:Furans; D017705:Lignans; D011714:Pyrans; C039281:furan