title: Open reduction and closed reduction internal fixation in treatment of femoral neck fractures: a meta-analysis.
abstract: BACKGROUND
  A meta-analysis was performed to assess the association between healing rate, avascular necrosis (AVN) of femoral head and two reductions-open reduction internal fixation (ORIF) and closed reduction internal fixation (CRIF) for femoral neck fracture.
  
  
  METHODS
  A literature-based search was conducted to identify all relevant studies published before September 10, 2013. The odd ratio (OR) and 95% confidence interval (CI) were used for estimating the effects of the two reduction methods. Data were independently extracted by two investigators who reached a consensus on all of the items. The heterogeneity between studies was examined by χ2-based Q statistic. Egger's regression analysis was used to evaluate publication bias. Statistical analysis was performed by Stata 10.0 software.
  
  
  RESULTS
  We examined 14 publications. The results of the present meta-analysis showed that AVN of femoral head were significant associated with the two reductions (CRIF vs. ORIF, OR=1.746, 95% CI 1.159-2.628, p=0.008), while the healing rate were not (CRIF vs. ORIF, OR=0.853, 95% CI 0.573-1.270, p=0.433).
  
  
  CONCLUSIONS
  The present meta-analysis indicated the risk of AVN of femoral head was significant higher after CRIF fixation compared with ORIF, but no association between the healing rate and the two reductions for femoral neck fracture.
authors.forename: Weiguo
authors.initials: W
authors.lastname: Wang
authors.forename: Junjie
authors.initials: J
authors.lastname: Wei
authors.affiliation: Department of Orthopaedics, The First Affiliated Hospital of Shandong University of Traditional Chinese Medicine, NO,16369, Jingshi Road, 250014 Jinan, China. zhanwangxu@hotmail.com.
authors.forename: Zhanwang
authors.initials: Z
authors.lastname: Xu
authors.forename: Wenkun
authors.initials: W
authors.lastname: Zhuo
authors.forename: Yuan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Hui
authors.initials: H
authors.lastname: Rong
authors.forename: Xuecheng
authors.initials: X
authors.lastname: Cao
authors.forename: Pingshan
authors.initials: P
authors.lastname: Wang
mesh_terms: D005265:Femoral Neck Fractures / Q000175:diagnosis / Q000601:surgery*; D005271:Femur Head Necrosis / Q000175:diagnosis / Q000209:etiology*; D005593:Fracture Fixation, Internal / Q000009:adverse effects* / Q000639:trends; D006801:Humans; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology*; D019651:Plastic Surgery Procedures / Q000009:adverse effects* / Q000639:trends; D016896:Treatment Outcome