title: Botulinum toxin clinic-based epidemiologic survey of adults with primary dystonia in East china.
abstract: OBJECTIVE
  Primary focal or segmental dystonia is a rare clinical condition. The clinical features of dystonia have not been evaluated in China. We performed a study to investigate the epidemiology of primary dystonia and its clinical variants in an adult population.
  
  
  METHODS
  A Botulinum Toxin Clinic-based study was conducted in the period 18 May through 8 October 2010 in East China. We identified 523 dystonia patients from the Movement disorders and Botulinum Toxin clinic Cases.
  
  
  RESULTS
  The most common focal dystonia were blepharospasm (59%), cervical dystonia (35%), limb dystonia (3%), oromandibular dystonia (2%) and laryngeal dystonia (1%). Males with primary dystonia were noted to have earlier age of onset. A female predominance was noted for most of the primary dystonias with a male to female ratio (M : F) ranging from 1 : 1.48 to 1 : 3.
  
  
  CONCLUSIONS
  The epidemiological features of dystonia in East China we collected were similar to the report in Japan which contrasts partly with that reported in Europe.
authors.affiliation: Department of Neurology, Sir Run Run Shaw Hospital of Zhejiang University School of Medicine, Zhejiang, China.
authors.forename: Li
authors.initials: L
authors.lastname: Wang
authors.affiliation: Department of Neurology, Sir Run Run Shaw Hospital of Zhejiang University School of Medicine, Zhejiang, China.
authors.forename: Xingyue
authors.initials: X
authors.lastname: Hu
authors.affiliation: Department of Neurology, The Second Affiliated Hospital of Suzhou University, Jiangsu, China.
authors.forename: Chunfeng
authors.initials: C
authors.lastname: Liu
authors.affiliation: Department of Neurology, Ruijin Hospital of Shanghai Jiao Tong University School of Medicine, Shanghai, China.
authors.forename: Yiwen
authors.initials: Y
authors.lastname: Wu
authors.affiliation: Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Anhui, China.
authors.forename: Changqing
authors.initials: C
authors.lastname: Wang
authors.affiliation: Department of Neurology, The First Affiliated Hospital of Fujian Medical University, Fujian, China.
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Neurology, Nanjing Brain Hospital, Nanjing Medical University, Jiangsu, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Chen
keywords: China; Epidemiology; Primary dystonia