title: Small cell lung cancer associated with solitary fibrous tumors of the pleura: a case study and literature review.
abstract: BACKGROUND
  Small cell lung cancer (SCLC) is the most aggressive type of lung cancer. The surgical treatment is possible only in a few and defined occasions. The association between SCLC and a solitary fibrous tumor of pleura (SFTP) is extremely rare.
  
  
  METHODS
  A 56 year-old man had a lung lesion (size 16 mm) FDG-avid (SUV 7.9) within upper lobe of right lung. No lymph adenopathy or other distant lesion were found. The pathological results of FNAB showed the presence of malignant cells inconclusive for a definitive diagnosis. Following thoracotomy, the exploration of pleural cavity showed an unexpected lesion (size. 3 cm) originating from parietal pleura and not radiologically seen. The intraoperative diagnosis was solitary fibrous tumor of the pleura. Then, an upper right lobectomy was achieved. The histological findings of the lung tumor diagnosed to be a SCLC (p-stage: T1N0M0). An adjuvant treatment was started. At 20 months after the procedure, no recurrence was found.
  
  
  CONCLUSIONS
  Surgery as part of multimodality treatment may be indicated in the treatment of SCLC in the early stage (T1N0M0). However, before proceeding to attend tumor resection an exploration of pleural cavity is mandatory in order to exclude any pleural involvement.
authors.affiliation: Department of Medicine and Surgery, University of Salerno, Baronissi, Salerno, S.C., Italy. Electronic address: vdicrescenzo@unisa.it.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Di Crescenzo
authors.affiliation: Department of Medicine and Surgery, University of Salerno, Baronissi, Salerno, S.C., Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Laperuta
authors.affiliation: Department of Medicine and Surgery, University of Salerno, Baronissi, Salerno, S.C., Italy.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Garzi
authors.affiliation: Department of Medicine and Surgery, University of Salerno, Baronissi, Salerno, S.C., Italy.
authors.forename: Filomena
authors.initials: F
authors.lastname: Napolitano
authors.affiliation: Department of Medicine and Surgery, University of Salerno, Baronissi, Salerno, S.C., Italy.
authors.forename: Annamaria
authors.initials: A
authors.lastname: Cascone
authors.affiliation: Department of Medicine and Surgery, University of Salerno, Baronissi, Salerno, S.C., Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Vatrella
mesh_terms: D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000601:surgery*; D055752:Small Cell Lung Carcinoma / Q000473:pathology / Q000601:surgery*; D054363:Solitary Fibrous Tumor, Pleural / Q000601:surgery*; D013908:Thoracotomy / Q000379:methods
keywords: Small cell lung cancer; Solitary fibrous tumor of pleura; Surgical treatment in early stage