title: [Small cell lung cancer associated with paraneoplastic bullous pemphigoid].
abstract: The broncho-pulmonary small cell carcinoma is the most common cancer provider paraneoplastic syndrome especially neurological and endocrine but also cutaneous syndrome. Paraneoplastic dermatosis do not result from a direct extension of cancer and are not metastases, but their presence is suggestive of an underlying tumor. The evolution of the dermatosis is parallel to that of cancer: treating cancer results in the regression of cutaneous manifestations. We report an observation of a 44-year-old smoker, who was hospitalized for a tissue excavated process associated with bullous dermatosis. The transmural puncture biopsy finds small cell carcinoma. The skin biopsy objective bullous pemphigoid. The evolution under chemotherapy was marked regression of bullous lesions and the patient died later after metastatic extension. Cutaneous paraneoplastic syndrome appears only in a minority of cancer patients, but its recognition is very important for early diagnosis.
authors.affiliation: Service des maladies respiratoires, hôpital du 20 Août 1953, CHU Ibn Rochd, Casablanca, Maroc. Electronic address: lakhdarnawal@gmail.com.
authors.forename: N
authors.initials: N
authors.lastname: Lakhdar
authors.affiliation: Service des maladies respiratoires, hôpital du 20 Août 1953, CHU Ibn Rochd, Casablanca, Maroc.
authors.forename: W
authors.initials: W
authors.lastname: El Khattabi
authors.affiliation: Service des maladies respiratoires, hôpital du 20 Août 1953, CHU Ibn Rochd, Casablanca, Maroc.
authors.forename: M
authors.initials: M
authors.lastname: Lahroussi
authors.affiliation: Service des maladies respiratoires, hôpital du 20 Août 1953, CHU Ibn Rochd, Casablanca, Maroc.
authors.forename: H
authors.initials: H
authors.lastname: Afif
authors.affiliation: Service des maladies respiratoires, hôpital du 20 Août 1953, CHU Ibn Rochd, Casablanca, Maroc.
authors.forename: A
authors.initials: A
authors.lastname: Aichane
mesh_terms: D000328:Adult; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000473:pathology; D008297:Male; D010257:Paraneoplastic Syndromes / Q000209:etiology*; D010391:Pemphigoid, Bullous / Q000209:etiology*; D055752:Small Cell Lung Carcinoma / Q000150:complications* / Q000175:diagnosis*
keywords: Bullous pemphigoid; Cancer pulmonaire à petites cellules; Paraneoplastic syndrome; Pemphigoïde bulleuse; Small cell lung cancer; Syndrome paranéoplasique