title: Applicability of EPR/alanine dosimetry for quality assurance in proton eye radiotherapy.
abstract: A new quality assurance and quality control method for proton eye radiotherapy based on electron paramagnetic resonance (EPR)/alanine dosimetry has been developed. It is based on Spread-Out Bragg Peak entrance dose measurement with alanine detectors. The entrance dose is well correlated with the dose at the facility isocenter, where, during the therapeutic irradiation, the tumour is placed. The unique alanine detector features namely keeping the dose record in a form of stable radiation-induced free radicals trapped in the material structure, and the non-destructive read-out makes this type of detector a good candidate for additional documentation of the patient's exposure over the therapy course.
authors.affiliation: The Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences, ul. Radzikowskiego 152, 31-342 Krakow, Poland barbara.michalec@ifj.edu.pl.
authors.forename: B
authors.initials: B
authors.lastname: Michalec
authors.affiliation: The Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences, ul. Radzikowskiego 152, 31-342 Krakow, Poland.
authors.forename: G
authors.initials: G
authors.lastname: Mierzwinska
authors.affiliation: The Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences, ul. Radzikowskiego 152, 31-342 Krakow, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Ptaszkiewicz
authors.affiliation: The Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences, ul. Radzikowskiego 152, 31-342 Krakow, Poland.
authors.forename: U
authors.initials: U
authors.lastname: Sowa
authors.affiliation: The Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences, ul. Radzikowskiego 152, 31-342 Krakow, Poland.
authors.forename: L
authors.initials: L
authors.lastname: Stolarczyk
authors.affiliation: Charité - Universitätsmedizin Berlin, Department of Ophthalmology CBF, BerlinProtonen am Helmholtz-Zentrum Berlin, Hahn-Meitner-Platz 1, 14109 Berlin, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Weber
mesh_terms: D000409:Alanine / Q000737:chemistry*; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods*; D005128:Eye Diseases / Q000532:radiotherapy*; D006801:Humans; D061766:Proton Therapy; D011785:Quality Assurance, Health Care; D011874:Radiometry / Q000379:methods*; D011879:Radiotherapy Dosage
chemical_list: D000409:Alanine