title: Deep vein thrombosis and tuberculosis: a causative link?
abstract: Pulmonary tuberculosis is very devastating in developing countries and its thrombogenic potential is a disturbing new entity. We report an 18-year-old woman who presented with a first episode of deep vein thrombosis. Pulmonary, hepatic and splenic tuberculosis was diagnosed while looking for secondary causes. The patient was treated with rifampicin, isoniazid, pyrazinamide and ethambutol along with low-molecular-weight heparin and antivitamin K. Tuberculosis has several mechanisms that induce a hypercoagulable state and can lead to thromboembolic complications.
authors.affiliation: Department of Internal Medicine, Charles Nicolle's Hospital, Tunis, Tunisia.
authors.forename: Ines
authors.initials: I
authors.lastname: Kechaou
authors.affiliation: Department of Internal Medicine, Charles Nicolle's Hospital, Tunis, Tunisia.
authors.forename: Eya
authors.initials: E
authors.lastname: Cherif
authors.affiliation: Department of Internal Medicine, Charles Nicolle's Hospital, Tunis, Tunisia.
authors.forename: Lamia
authors.initials: L
authors.lastname: Ben Hassine
authors.affiliation: Department of Internal Medicine, Charles Nicolle's Hospital, Tunis, Tunisia.
authors.forename: Narjess
authors.initials: N
authors.lastname: Khalfallah
mesh_terms: D000293:Adolescent; D000925:Anticoagulants / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D019851:Thrombophilia / Q000097:blood / Q000188:drug therapy; D014386:Tuberculosis, Hepatic / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D014397:Tuberculosis, Pulmonary / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D014400:Tuberculosis, Splenic / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D020246:Venous Thrombosis / Q000097:blood / Q000150:complications* / Q000188:drug therapy
chemical_list: D000925:Anticoagulants; D000995:Antitubercular Agents