title: A rare case of pituitary infarction leading to spontaneous tumour resolution and CSF-sella syndrome in an 11-year-old girl and a review of the paediatric literature.
abstract: Pituitary infarction or apoplexy with spontaneous cure of the underlying pituitary adenoma is rare. In the paediatric population, we found only a few reported cases. We report a rare case of pituitary infarction progressing to CSF-sella syndrome (or empty sella) in an 11-year-old girl. She presented with sudden onset vomiting, moderate headaches, lethargy, weight loss, and tall stature above her mid-parental height. She did not have any severe symptoms of apoplexy. Her clinical and radiological findings suggested infarction of a pituitary lesion, such as a pituitary adenoma or infarction of a cystic lesion, such as a Rathke's cleft cyst. In this report, we discuss her case of probable infarction of a growth hormone secreting adenoma with a phase of accelerated growth ending up with total anterior pituitary insufficiency. The differential diagnosis and review of the rare cases of paediatric pituitary infarction in the literature will be discussed.
authors.forename: Vicki E
authors.initials: VE
authors.lastname: Maltby
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Crock
authors.forename: Dieter K
authors.initials: DK
authors.lastname: Lüdecke
mesh_terms: D020520:Brain Infarction / Q000150:complications*; D002648:Child; D004652:Empty Sella Syndrome / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D010899:Pituitary Apoplexy / Q000150:complications* / Q000473:pathology; D010911:Pituitary Neoplasms / Q000150:complications* / Q000473:pathology; D012075:Remission, Spontaneous