title: HIV incidence and risk factors in Chinese young men who have sex with men--a prospective cohort study.
abstract: OBJECTIVE
  To assess HIV incidence and its associated risk factors among young men who have sex with men (YMSM) in urban areas, China.
  
  
  METHODS
  The study used a prospective cohort study design and standard diagnostic tests.
  
  
  METHODS
  A twelve-month prospective cohort study was conducted among YMSM (18-25 years old) in 8 large cities in China. The participants were recruited via snowball sampling. A total of 1102 HIV-negative YMSM completed baseline assessment, 878 YMSM participants completed 6-month follow-up, and 902 completed 12-month follow-up. HIV was screened by an enzyme-linked immunosorbent assay and confirmed with Western Blot. Syphilis was screened via rapid plasma reagent and confirmed by treponema pallidum particle agglutination assay.
  
  
  RESULTS
  78 HIV seroconversions were identified within 1168.4 person-year observations yielding an incidence rate of 6.7 per 100 person-years. HIV seroconversion was associated with non-student status (RR = 2.61, 90% CI = 1.3-5.26), low HIV transmission knowledge (RR = 8.87, 90% CI = 2.16-36.43), and syphilis infection (RR = 5.04, 90% CI = 2.57-9.90).
  
  
  CONCLUSIONS
  Incidence of HIV among YMSM is high in urban areas of China. Interventions measures are required to contain the HIV epidemic within this population.
authors.affiliation: School of Public Health, Anhui Medical University, Hefei, Anhui Province, China.
authors.forename: Zhenxin
authors.initials: Z
authors.lastname: Dong
authors.affiliation: National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Xu
authors.affiliation: School of Public Health, Anhui Medical University, Hefei, Anhui Province, China.
authors.forename: Hongbo
authors.initials: H
authors.lastname: Zhang
authors.affiliation: National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Dou
authors.affiliation: National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
authors.forename: Guodong
authors.initials: G
authors.lastname: Mi
authors.affiliation: National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
authors.forename: Yuhua
authors.initials: Y
authors.lastname: Ruan
authors.affiliation: Guizhou Provincial Center for Disease Control and Prevention, Guizhou, China.
authors.forename: Limei
authors.initials: L
authors.lastname: Shen
authors.affiliation: Yunnan Provincial Center for Disease Control and Prevention, Yunnan, China.
authors.forename: Xiangdong
authors.initials: X
authors.lastname: Min
authors.affiliation: Guangxi Provincial Center for Disease Control and Prevention, Guangxi, China.
authors.forename: Guanghua
authors.initials: G
authors.lastname: Lan
authors.affiliation: Xinjiang Center for Disease Control and Prevention, Xinjiang, China.
authors.forename: Fan
authors.initials: F
authors.lastname: Li
authors.affiliation: Sichuan Provincial Center for Disease Control and Prevention, Sichuan, China.
authors.forename: Tian
authors.initials: T
authors.lastname: Li
authors.affiliation: Shanghai Center for Disease Control and Prevention, Shanghai, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Ning
authors.affiliation: Chongqing Center for Disease Control and Prevention, Chongqing, China.
authors.forename: Guohui
authors.initials: G
authors.lastname: Wu
authors.affiliation: School of Public Health, Anhui Medical University, Hefei, Anhui Province, China.
authors.forename: Min
authors.initials: M
authors.lastname: She
authors.affiliation: National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
authors.forename: Zunyou
authors.initials: Z
authors.lastname: Wu
mesh_terms: D000293:Adolescent; D000328:Adult; D002681:China / Q000453:epidemiology; D002947:Cities / Q000453:epidemiology; D015331:Cohort Studies; D015658:HIV Infections / Q000453:epidemiology*; D006679:HIV Seropositivity / Q000453:epidemiology; D018451:Homosexuality, Male / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D008297:Male; D011446:Prospective Studies; D012307:Risk Factors; D055815:Young Adult