title: Novel multiple mutations in the topoisomerase gene of Haitian variant Vibrio cholerae O1.
authors.affiliation: Cholera Research Lab, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India.
authors.forename: M P
authors.initials: MP
authors.lastname: Divya
authors.affiliation: Bioinformatics Facility, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India.
authors.forename: K C
authors.initials: KC
authors.lastname: Sivakumar
authors.affiliation: Government Medical College Hospital, Kozhikode, Kerala, India.
authors.forename: K L
authors.initials: KL
authors.lastname: Sarada Devi
authors.affiliation: Government Medical College Hospital, Kozhikode, Kerala, India.
authors.forename: S
authors.initials: S
authors.lastname: Remadevi
authors.affiliation: Cholera Research Lab, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India sabu@rgcb.res.in.
authors.forename: Sabu
authors.initials: S
authors.lastname: Thomas
mesh_terms: D000595:Amino Acid Sequence; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D001483:Base Sequence; D002771:Cholera / Q000188:drug therapy / Q000382:microbiology; D002772:Cholera Toxin / Q000235:genetics; D002939:Ciprofloxacin / Q000737:chemistry / Q000494:pharmacology; D027101:DNA Topoisomerase IV / Q000737:chemistry / Q000235:genetics*; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D036781:Fimbriae Proteins / Q000235:genetics; D006801:Humans; D007194:India; D008826:Microbial Sensitivity Tests; D062105:Molecular Docking Simulation; D008969:Molecular Sequence Data; D058885:Multilocus Sequence Typing; D009154:Mutation; D013816:Thermodynamics; D041241:Vibrio cholerae O1 / Q000187:drug effects / Q000201:enzymology / Q000235:genetics* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; C085807:TcpA protein, Vibrio cholerae; D036781:Fimbriae Proteins; D002939:Ciprofloxacin; D002772:Cholera Toxin; D027101:DNA Topoisomerase IV