title: 25-gauge microincision vitrectomy to treat vitreoretinal disease in glaucomatous eyes after trabeculectomy.
abstract: Purpose. To determine the feasibility of using 25-gauge microincision vitrectomy surgery (25GMIVS) to treat vitreoretinal disease in glaucomatous eyes which have previously undergone trabeculectomy (TLE). Methods. A consecutive, interventional case series. We performed 25GMIVS in 15 glaucomatous eyes that had undergone TLE. Follow-up period was 11.5 months. Results. 25GMIVS was successfully used and led to improvement in visual acuity (P < 0.01). We performed 25GMIVS for proliferative diabetic retinopathy with neovascular glaucoma in 53% of eyes (8 of 15). Although 3 eyes needed further TLE following 25GMIVS, final IOP was below 21 mmHg in all eyes except one eye (93%) and was comparable to pre-25GMIVS IOP (P = 0.20) without an increase in the number of glaucoma medications (P = 0.14). Conclusions. 25GMIVS is a feasible treatment for vitreoretinal disease in eyes with preexisting TLE, effective in both significantly improving BCVA and preserving the filtering bleb, while not excluding further glaucoma surgery.
authors.affiliation: Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan.
authors.forename: Hiroshi
authors.identifier: 0000-0003-0642-793X
authors.initials: H
authors.lastname: Kunikata
authors.affiliation: Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan.
authors.forename: Naoko
authors.initials: N
authors.lastname: Aizawa
authors.affiliation: Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Sendai 980-8573, Japan.
authors.forename: Nobuo
authors.identifier: 0000-0003-0237-4746
authors.initials: N
authors.lastname: Fuse
authors.affiliation: Division of Clinical Cell Therapy, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
authors.forename: Toshiaki
authors.identifier: 0000-0003-4666-5078
authors.initials: T
authors.lastname: Abe
authors.affiliation: Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan.
authors.forename: Toru
authors.initials: T
authors.lastname: Nakazawa