title: A new technique for performing endoscopic pyloromyotomy by gastric submucosal tunnel dissection.
abstract: OBJECTIVE
  To investigate the feasibility of a new endoscopic pyloromyotomy technique.
  
  
  METHODS
  Endoscopic pyloromyotomy through a gastric submucosal tunnel was performed in 6 pigs. At the greater curvature, 2 cm proximal to the pylorus, we incised the mucosa and dissected the submucosal tunnel up to the pyloric ring. The pyloric muscular ring was sectioned, and then the gastric mucosal incision was closed with metallic clips. The pigs were then euthanized and necropsies were performed.
  
  
  RESULTS
  Section of the pyloric ring was successful in all 6 pigs. Small perforations occurred in 2 of the pigs, and there was limited bleeding in 1 pig. Necropsy and histologic evaluation confirmed the pyloric section.
  
  
  CONCLUSIONS
  This technique is feasible, easy to perform, and maybe alternative to pyloroplasty in selected cases. Experimental comparative studies with other techniques still must be performed.
authors.affiliation: *Serviço de Endoscopia Gastrointestinal-Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo †Department of Pathology, University of São Paulo, School of Medicine, São Paulo, SP, Brazil.
authors.forename: Dalton M
authors.initials: DM
authors.lastname: Chaves
authors.forename: Carla C
authors.initials: CC
authors.lastname: Gusmon
authors.forename: Luiz H M
authors.initials: LH
authors.lastname: Mestieri
authors.forename: Eduardo G H
authors.initials: EG
authors.lastname: de Moura
authors.forename: Mariana M
authors.initials: MM
authors.lastname: Veras
authors.forename: Fernanda C S
authors.initials: FC
authors.lastname: Pessorrusso
authors.forename: Paulo
authors.initials: P
authors.lastname: Sakai
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004210:Dissection / Q000379:methods*; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D005240:Feasibility Studies; D005500:Follow-Up Studies; D005746:Gastric Emptying; D005753:Gastric Mucosa / Q000601:surgery*; D017219:Gastric Outlet Obstruction / Q000503:physiopathology / Q000601:surgery*; D015391:Gastroplasty / Q000379:methods*; D011708:Pylorus / Q000601:surgery*; D012189:Retrospective Studies; D013552:Swine; D016896:Treatment Outcome