title: Collision tumor of low-grade B-cell lymphoma and adenocarcinoma with tuberculosis in the colon: a case report and literature review.
abstract: This report presents a case of collision tumors of low-grade B-cell lymphoma and adenocarcinoma in the sigmoid colon of an 81-year-old man. All surgically resected regional mesenteric lymph nodes were found to be occupied by low-grade B-cell lymphoma, and one lymph node showed the presence of adenocarcinoma. Low-grade B-cell lymphoma was also observed in the resected spleen. Moreover, concurrent tuberculosis infection in the resected colon was proven by the presence of positive results obtained with polymerase chain reaction analysis of the mycobacterial DNA. Systemic chemotherapy was administered for advanced colon cancer with lung metastasis, and anti-tuberculosis treatment was also prescribed. The occurrence of synchronous lymphoma and adenocarcinoma of the colorectal region is rare. Furthermore, collisions of these different entities are also extremely unusual. The accurate clinical determination of the dominant tumor and a timely follow-up are required for the proper treatment of these cases.
authors.forename: Hung-Hsin
authors.initials: HH
authors.lastname: Lin
authors.forename: Jeng-Kai
authors.initials: JK
authors.lastname: Jiang
authors.affiliation: Division of Colon & Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital, No 201, Sec, 2, Shih-Pai Road, Taipei 11217, Taiwan. jklin@vghtpe.gov.tw.
authors.forename: Jen-Kou
authors.initials: JK
authors.lastname: Lin
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000473:pathology*; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D012809:Colon, Sigmoid / Q000473:pathology*; D003110:Colonic Neoplasms / Q000188:drug therapy / Q000473:pathology*; D004269:DNA, Bacterial / Q000235:genetics; D004359:Drug Therapy, Combination; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary*; D016393:Lymphoma, B-Cell / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D009161:Mycobacterium / Q000235:genetics / Q000302:isolation & purification; D060787:Neoplasm Grading; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy / Q000473:pathology*; D016133:Polymerase Chain Reaction; D011379:Prognosis; D014376:Tuberculosis / Q000175:diagnosis* / Q000382:microbiology
chemical_list: D000995:Antitubercular Agents; D004269:DNA, Bacterial