title: Treatment of malignant gliomas in elderly patients: a concise overview of the literature.
abstract: Gliomas are the most frequent primary brain tumors and the incidence data has increased in the elderly population. Unfortunately, prospective studies on this population are few and so the right treatment is unknown. In the elderly patients no standard treatment has been established and therefore the optimal treatment should be individualized. We performed a review analyzing the prognostic and predictive factors, the clinical studies, and the correct management of this population.
authors.affiliation: Medical Oncology 1 Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.
authors.forename: Patrizia
authors.initials: P
authors.lastname: Farina
authors.affiliation: Medical Oncology 1 Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Lombardi
authors.affiliation: Medical Oncology 1 Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.
authors.forename: Eleonora
authors.initials: E
authors.lastname: Bergo
authors.affiliation: Medical Oncology 1 Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Roma
authors.affiliation: Medical Oncology 1 Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.
authors.forename: Vittorina
authors.initials: V
authors.lastname: Zagonel
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000453:epidemiology / Q000235:genetics / Q000503:physiopathology / Q000628:therapy*; D003071:Cognition; D005910:Glioma / Q000453:epidemiology / Q000235:genetics / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D011379:Prognosis; D011788:Quality of Life