title: Prevalence of acute cardiac disorders in patients with suspected ST-segment elevation myocardial infarction and non-significant coronary artery disease.
abstract: OBJECTIVE
  We aimed to study the prevalence of acute cardiac disorders in patients with suspected ST-segment elevation myocardial infarction (STEMI) and non-significant coronary artery disease (CAD).
  
  
  METHODS
  From January to October 2012 we consecutively included patients admitted with suspected STEMI and non-significant CAD (coronary artery stenosis diameter <50%). Patients were diagnosed with acute cardiac disorder in the presence of elevated cardiac biomarkers (troponin T >50ng/l or creatine kinase MB >4μg/l) or dynamic ECG changes (ST-segment changes or T-wave inversion).
  
  
  RESULTS
  Of the 871 patients admitted with suspected STEMI, 11% (n=95) had non-significant CAD. Of these, 67% (n=64) had elevated cardiac biomarkers or dynamic ECG changes and were accordingly diagnosed with acute cardiac disorders. In the remaining 33% (n=31) of patients, cardiac biomarkers were normal and ECG changes remained stationary.
  
  
  CONCLUSIONS
  Acute cardiac disorders were diagnosed in two thirds of patients with suspected STEMI and non-significant CAD.
authors.affiliation: Department of Cardiology, The Heart Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: hedvig.andersson@regionh.dk.
authors.forename: H
authors.initials: H
authors.lastname: Andersson
authors.affiliation: Department of Cardiology, The Heart Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; Department of Clinical Physiology, Nuclear Medicine and PET, Diagnostic Centre, Copenhagen University Hospital, Copenhagen, Denmark.
authors.forename: T E
authors.initials: TE
authors.lastname: Christensen
authors.affiliation: Department of Cardiology, The Heart Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
authors.forename: K A
authors.initials: KA
authors.lastname: Ahtarovski
authors.affiliation: Department of Cardiology, The Heart Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
authors.forename: L E
authors.initials: LE
authors.lastname: Bang
authors.affiliation: Department of Clinical Physiology, Nuclear Medicine and PET, Diagnostic Centre, Copenhagen University Hospital, Copenhagen, Denmark.
authors.forename: P
authors.initials: P
authors.lastname: Hasbak
authors.affiliation: Department of Cardiology, The Heart Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
authors.forename: N
authors.initials: N
authors.lastname: Vejlstrup
authors.affiliation: Department of Cardiology, The Heart Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
authors.forename: F
authors.initials: F
authors.lastname: Pedersen
authors.affiliation: Department of Cardiology, The Heart Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
authors.forename: L
authors.initials: L
authors.lastname: Holmvang
authors.affiliation: Department of Cardiology, The Heart Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
authors.forename: P
authors.initials: P
authors.lastname: Grande
authors.affiliation: Department of Cardiology, The Heart Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
authors.forename: P
authors.initials: P
authors.lastname: Clemmensen
authors.affiliation: Department of Medicine, division of Cardiology, Duke University Medical, Center, Durham, NC, USA.
authors.forename: G S
authors.initials: GS
authors.lastname: Wagner
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D015984:Causality; D015897:Comorbidity; D003324:Coronary Artery Disease / Q000097:blood / Q000175:diagnosis* / Q000401:mortality*; D003718:Denmark / Q000453:epidemiology; D004562:Electrocardiography / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000175:diagnosis* / Q000401:mortality*; D015995:Prevalence; D012307:Risk Factors; D017678:Sex Distribution; D015996:Survival Rate; D020107:Troponin T / Q000097:blood*; D055815:Young Adult
chemical_list: D015415:Biomarkers; D020107:Troponin T
keywords: Acute cardiac disorders; Non-significant coronary artery disease; ST-segment elevation myocardial infarction