title: An adult patient with common B-cell acute lymphoblastic leukaemia who presented with pancreatic involvement, description of the second adult case and review of paediatric cases.
abstract: Pancreatic involvement in acute lymphoblastic leukaemia (ALL) may go unrecognised. There are only a few paediatric cases; nevertheless, presentation with pancreatic involvement in an adult patient with ALL has been reported rarely. Our 52-year-old male patient came to us with abdominal pain, nausea and vomiting; he had pancreatic enlargement on CT. He was diagnosed with common B-cell ALL with pancreatic involvement. The patient obtained haematological remission and the pancreatic enlargement regressed after chemotherapy, but later he had central nervous system and liver relapses. He died 6 months after diagnosis because of progressive pneumonia and chemotherapy-resistant ALL with multiple extramedullary relapses.
authors.affiliation: Department of Hematology, Trakya University Medicine Faculty, Edirne, Turkey.
authors.forename: Gulsum Emel
authors.initials: GE
authors.lastname: Pamuk
authors.affiliation: Department of Internal Medicine, Steward Carney Hospital, Tufts University School of Medicine, Boston, Massachusetts, USA.
authors.forename: Umit
authors.initials: U
authors.lastname: Tapan
authors.affiliation: Department of Radiodiagnostics, Bakirkoy Dr.Sadi Konuk Education and Research Hospital, Istanbul, Turkey.
authors.forename: Sema
authors.initials: S
authors.lastname: Aksoy
authors.affiliation: Department of Gastroenterology, Trakya University Medical Faculty, Edirne, Turkey.
authors.forename: Hasan
authors.initials: H
authors.lastname: Umit
mesh_terms: D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000000981:diagnostic imaging*; D019283:Pancreatitis, Acute Necrotizing / Q000175:diagnosis / Q000209:etiology*; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000175:diagnosis; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed