title: Stability of nitrofuran residues during honey processing and nitrofuran removal by macroporous adsorption resins.
abstract: There is increasing concern that the presence of antibiotics such as nitrofurans in animal-derived food products is harmful to human. This study originally assessed the effects of different honey processing steps on the stabilities of four nitrofuran metabolites (3-amino-2-oxazolidone, 1-aminohydantonin, semicarbazide and 3-amino-5-morpholinomethyl-2-oxazolidone). Macroporous adsorption resins (MARs) were evaluated for the removal of these residues. Nitrofuran metabolites were analysed by LC-MS/MS after each processing step. The results revealed that honey processing reduced nitrofuran metabolites in honey and the total loss was from 56.6% to 90.4%. Furthermore, LS-901 was the optimum MAR with adsorption rates of 69.9-91.8% for four metabolites. After removing nitrofuran metabolites, the honey could be safely used as winter feed for honeybees.
authors.affiliation: Department of Food Science and Engineering, School of Chemical Engineering, Northwest University, Xi'an 710069, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Jia
authors.affiliation: Xi'an Analytical and Monitoring Centre for Agri-food Quality Safety, Xi'an 710077, China.
authors.forename: Shifeng
authors.initials: S
authors.lastname: Yu
authors.affiliation: Department of Food Science and Engineering, School of Chemical Engineering, Northwest University, Xi'an 710069, China.
authors.forename: Ni
authors.initials: N
authors.lastname: Cheng
authors.affiliation: Institute of Apiculture Research, Chinese Academy of Agricultural Sciences, Beijing 100093, China.
authors.forename: Liming
authors.initials: L
authors.lastname: Wu
authors.affiliation: Department of Food Science and Engineering, School of Chemical Engineering, Northwest University, Xi'an 710069, China.
authors.forename: Jiajia
authors.initials: J
authors.lastname: Jia
authors.affiliation: Institute of Apiculture Research, Chinese Academy of Agricultural Sciences, Beijing 100093, China. Electronic address: xue_xiaofeng@126.com.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Xue
authors.affiliation: Department of Food Science and Engineering, School of Chemical Engineering, Northwest University, Xi'an 710069, China. Electronic address: caowei@nwu.edu.cn.
authors.forename: Wei
authors.initials: W
authors.lastname: Cao
mesh_terms: D000327:Adsorption; D002853:Chromatography, Liquid / Q000379:methods*; D005506:Food Contamination / Q000032:analysis*; D006722:Honey / Q000032:analysis*; D013058:Mass Spectrometry / Q000379:methods*; D009581:Nitrofurans / Q000737:chemistry*
chemical_list: D009581:Nitrofurans
keywords: Honey; Macroporous adsorption resins; Nitrofurans; Processing; Removal