title: Electrophysiological, hemodynamic, and metabolic response to open procedure or endovascular repair of infrarenal aortic aneurysms.
abstract: BACKGROUND
  The occurrence of cardiovascular diseases in the group of patients undergoing vascular surgery because of abdominal aorta aneurysm is very high. Endovascular procedures are regarded as hemodynamically safer for the patients. The aim of this study was to compare the changes in electrophysiological, hemodynamic, and metabolic parameters depending on the type of operation, using invasive hemodynamic monitoring and Holter electrocardiography recording.
  
  
  METHODS
  A prospective, observational, nonrandomized study was conducted to compare dynamic changes of electrophysiological parameters (dominant rhythm, arrhythmia, corrected QT interval (QTc), invasive blood pressure, electrolytes, and acid-base balance in defined points during perioperative time in 2 groups: vascular prosthesis implantation group (91 patients) and stent-graft implantation group (83 patients).
  
  
  RESULTS
  The study group comprised 174 consecutive adult Caucasian patients (mean age 64.4 ± 8.9 years in stent-graft group and 70.0 ± 7.5 years in vascular prosthesis implantation group). Although patients in the stent-graft implantation group were younger, they were diagnosed with lower limbs vascular atherosclerosis, type 2 diabetes mellitus, and a lower left ventricle ejection fraction more often than patients in the open procedure group. During the open procedure, higher blood pressure amplitudes (P = 0.00009), higher decrease in pH (P = 0.049), increase in the arterial lactate level (P = 0.00002), prolonged QTc values (P = 0.001), more frequent ventricular extrasystoles (P = 0.005), and cardiovascular deaths were observed, when compared with those observed during the endovascular aneurysm repair.
  
  
  CONCLUSIONS
  When compared with the chosen techniques, the one for infrarenal abdominal aneurysm was found to be associated with significant differences in electrophysiological, hemodynamic, and metabolic parameters.
authors.affiliation: Clinic of Anesthesiology and Intensive Care, Pomeranian Medical University, Szczecin, Poland.
authors.forename: Jowita
authors.initials: J
authors.lastname: Biernawska
authors.affiliation: Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, Szczecin, Poland.
authors.forename: Mariusz
authors.initials: M
authors.lastname: Kaczmarczyk
authors.affiliation: Clinic of Anesthesiology and Intensive Care, Pomeranian Medical University, Szczecin, Poland. Electronic address: k.kotfis@wp.pl.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Kotfis
authors.affiliation: Clinic of Vascular Surgery, Pomeranian Medical University, Szczecin, Poland.
authors.forename: Miłosław
authors.initials: M
authors.lastname: Cnotliwy
authors.affiliation: Clinic of Anesthesiology and Intensive Care, Pomeranian Medical University, Szczecin, Poland.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Zegan-Barańska
authors.affiliation: Clinic of Anesthesiology and Intensive Care, Pomeranian Medical University, Szczecin, Poland.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Zukowska
authors.affiliation: Clinic of Anesthesiology and Intensive Care, Pomeranian Medical University, Szczecin, Poland.
authors.forename: Arkadiusz
authors.initials: A
authors.lastname: Greczan
authors.affiliation: Clinic of Anesthesiology and Intensive Care, Pomeranian Medical University, Szczecin, Poland.
authors.forename: Maciej
authors.initials: M
authors.lastname: Zukowski
mesh_terms: D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000401:mortality / Q000601:surgery*; D015415:Biomarkers / Q000097:blood; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods* / Q000401:mortality; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D015716:Electrocardiography, Ambulatory; D004594:Electrophysiology; D057510:Endovascular Procedures / Q000401:mortality; D005260:Female; D006439:Hemodynamics; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007773:Lactates / Q000097:blood; D008297:Male; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D011183:Postoperative Complications / Q000453:epidemiology; D011446:Prospective Studies; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D007773:Lactates