title: Clinical Trials without conceptual foundation may produce flawed results for the management of fluid therapy in the critically ill.
authors.affiliation: Department of Critical Care Medicine, University of Pittsburgh, 606 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA.
authors.forename: M R
authors.initials: MR
authors.lastname: Pinsky
mesh_terms: D002986:Clinical Trials as Topic / Q000592:standards*; D003245:Consensus Statements as Topic; D016638:Critical Illness / Q000628:therapy*; D019317:Evidence-Based Medicine; D005440:Fluid Therapy / Q000592:standards*; D006801:Humans; D012107:Research Design