title: Lynch syndrome 101 (years, that is).
abstract: Lynch syndrome was described over a century ago but information on the medical consequences and optimal management of this disorder continue to amass and evolve. This brief overview highlights the gene-specific and site-specific cancer penetrance and management options for those with Lynch syndrome.
authors.affiliation: From the Department of Health Sciences Research, Mayo Clinic, Scottsdale, AZ.
authors.forename: Noralane M
authors.initials: NM
authors.lastname: Lindor
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor / Q000235:genetics; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000453:epidemiology / Q000235:genetics / Q000266:history / Q000473:pathology / Q000628:therapy*; D020022:Genetic Predisposition to Disease; D040941:Heredity; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D025202:Molecular Diagnostic Techniques; D010375:Pedigree; D010641:Phenotype; D011237:Predictive Value of Tests; D015995:Prevalence; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor