title: Rhodium-catalyzed intramolecular annulation via C-H activation leading to fused tricyclic indole scaffolds.
abstract: The rhodium(III)-catalyzed intramolecular annulation of alkyne-tethered acetanilides for the synthesis of fused tricyclic indole scaffolds via C-H activation has been developed, which has the potential for the synthesis of many indole alkaloids. This reaction proceeds under mild reaction conditions and with tolerance to a variety of functional groups.
authors.affiliation: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China. yxjia@bjmu.edu.cn.
authors.forename: Pengyu
authors.initials: P
authors.lastname: Tao
authors.forename: Yanxing
authors.initials: Y
authors.lastname: Jia
mesh_terms: D007211:Indoles / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*
chemical_list: D007211:Indoles; D012238:Rhodium