title: The arachnoid granulations of the newborn human: An ultrastructural study.
abstract: Portions of the superior sagittal sinus and lacunae laterales containing arachnoid villi and granulations from 8 full-term newborn babies were studied by transmission electron microscopy. Arachnoid proliferations from 3 subjects were distended and fixed in vitro by applying a differential pressure of 8 cm H2O to the subarachnoid aspect of the tissues. The remaining cases were fixed in a collapsed state. Distended arachnoid proliferations showed morphologic characteristics associated with similar functional structures in experimental animals: shortened and enlarged interendothelial spaces; micropinocytotic activity and a system of endothelial-lined tubules. All this is taken as evidence that arachnoid proliferations in newborn babies could already be engaged in cerebrospinal fluid absorption.
authors.affiliation: Department of Radiology and William H. Harkness Research Building, Cornell University Medical College, New York, NY 10021 U.S.A.; Department of Pathology, Division of Health Sciences, Universidad del Valle, Cali, Colombia.
authors.forename: D G
authors.initials: DG
authors.lastname: Gomez
authors.affiliation: Department of Radiology and William H. Harkness Research Building, Cornell University Medical College, New York, NY 10021 U.S.A.; Department of Pathology, Division of Health Sciences, Universidad del Valle, Cali, Colombia.
authors.forename: J E
authors.initials: JE
authors.lastname: Ehrmann
authors.affiliation: Department of Radiology and William H. Harkness Research Building, Cornell University Medical College, New York, NY 10021 U.S.A.; Department of Pathology, Division of Health Sciences, Universidad del Valle, Cali, Colombia.
authors.forename: D
authors.initials: D
authors.lastname: Gordon Potts
authors.affiliation: Department of Radiology and William H. Harkness Research Building, Cornell University Medical College, New York, NY 10021 U.S.A.; Department of Pathology, Division of Health Sciences, Universidad del Valle, Cali, Colombia.
authors.forename: A M
authors.initials: AM
authors.lastname: Pavese
authors.affiliation: Department of Radiology and William H. Harkness Research Building, Cornell University Medical College, New York, NY 10021 U.S.A.; Department of Pathology, Division of Health Sciences, Universidad del Valle, Cali, Colombia.
authors.forename: A
authors.initials: A
authors.lastname: Gilanian