title: Application of N-doped graphene modified carbon ionic liquid electrode for direct electrochemistry of hemoglobin.
abstract: Nitrogen-doped graphene (NG) was synthesized and used for the investigation on direct electrochemistry of hemoglobin (Hb) with a carbon ionic liquid electrode as the substrate electrode. Due to specific characteristics of NG such as excellent electrocatalytic property and large surface area, direct electron transfer of Hb was realized with enhanced electrochemical responses appearing. Electrochemical behaviors of Hb on the NG modified electrode were carefully investigated with the electrochemical parameters calculated. The Hb modified electrode exhibited excellent electrocatalytic reduction activity toward different substrates, such as trichloroacetic acid and H2O2, with wider dynamic range and lower detection limit. These findings show that NG can be used for the preparation of chemically modified electrodes with improved performance and has potential applications in electrochemical sensing.
authors.affiliation: College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, PR China. Electronic address: swyy26@hotmail.com.
authors.forename: Wei
authors.initials: W
authors.lastname: Sun
authors.affiliation: College of Materials Science and Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China; Department of Physics, Astronomy, and Materials Science, Missouri State University, Springfield, MO 65897, USA. Electronic address: donglifeng@qust.edu.cn.
authors.forename: Lifeng
authors.initials: L
authors.lastname: Dong
authors.affiliation: College of Materials Science and Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Deng
authors.affiliation: College of Materials Science and Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China.
authors.forename: Jianhua
authors.initials: J
authors.lastname: Yu
authors.affiliation: College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, PR China.
authors.forename: Wencheng
authors.initials: W
authors.lastname: Wang
authors.affiliation: College of Materials Science and Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China.
authors.forename: Qianqian
authors.initials: Q
authors.lastname: Zhu
mesh_terms: D048271:Chitosan / Q000737:chemistry; D004563:Electrochemistry / Q000379:methods*; D004566:Electrodes; D004579:Electron Transport; D006108:Graphite / Q000138:chemical synthesis*; D006454:Hemoglobins / Q000032:analysis*; D052578:Ionic Liquids / Q000138:chemical synthesis*; D057230:Limit of Detection; D009584:Nitrogen / Q000737:chemistry; D014238:Trichloroacetic Acid
chemical_list: D006454:Hemoglobins; D052578:Ionic Liquids; D014238:Trichloroacetic Acid; D006108:Graphite; D048271:Chitosan; D009584:Nitrogen
keywords: Carbon ionic liquid electrode; Direct electrochemistry; Hemoglobin; N-doped graphene