title: Contact dermatitis to cobalt chloride with an unusual mechanism.
abstract: BACKGROUND
  Contact dermatitis is a frequent inflammatory skin disease. A suspected diagnosis is based on clinical symptoms, a plausible contact to allergens and a suitable history of dermatitis. Therefore, careful diagnosis by patch testing is of great importance because the patch testing is important to find out which allergen/material causes the complaints. Metallic allergens such as cobalt are among the most common causes of allergic contact dermatitis, but frequencies of contact dermatitis to these allergens may vary in different skin areas. Here, we report an unusual case of cobalt allergy on the skin contact with the prosthetic leg of a 30-year-old female patient.
  
  
  METHODS
  The patient developed maculopapular and vesicular lesions on her contact region of residual limb to prosthetic leg.
  
  
  RESULTS
  She underwent standard patch testing, which resulted in a strong positive reaction to cobalt chloride.
  
  
  CONCLUSIONS
  This case report may serve to remind doctors to be aware of potential allergic reactions to prostheses and to enable them to recognize a metal allergy if it appears. Prosthetists should also be reminded of potential allergic reactions.
  
  
  CONCLUSIONS
  Cobalt can be used as an accelerator in making a prosthetic socket. Several cases have been reported concerning allergies to components of the prosthetic socket. This is the first report of sensitization to cobalt which is used in making a prosthetic leg.
authors.affiliation: Medical Faculty, Division of Immunology and Allergic Disease, Necmettin Erbakan University, Konya, Turkey arslansevket@hotmail.com.
authors.forename: Sevket
authors.initials: S
authors.lastname: Arslan
authors.affiliation: Medical Faculty, Division of Immunology and Allergic Disease, Necmettin Erbakan University, Konya, Turkey.
authors.forename: Serkan
authors.initials: S
authors.lastname: Aksan
authors.affiliation: Medical Faculty, Division of Immunology and Allergic Disease, Necmettin Erbakan University, Konya, Turkey.
authors.forename: Ramazan
authors.initials: R
authors.lastname: Ucar
authors.affiliation: Medical Faculty, Division of Immunology and Allergic Disease, Necmettin Erbakan University, Konya, Turkey.
authors.forename: Ahmet Zafer
authors.initials: AZ
authors.lastname: Caliskaner
mesh_terms: D000328:Adult; D000485:Allergens / Q000009:adverse effects*; D001186:Artificial Limbs / Q000009:adverse effects*; D003035:Cobalt / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000209:etiology*; D005260:Female; D005266:Femoral Neoplasms / Q000601:surgery; D006801:Humans; D012516:Osteosarcoma / Q000601:surgery; D011474:Prosthesis Design / Q000009:adverse effects*
chemical_list: D000485:Allergens; D003035:Cobalt; C018021:cobaltous chloride
keywords: Contact dermatitis; cobalt; prosthetic leg