title: Investigation of the 8-hydroxy-2'-deoxyguanosine, total antioxidant and nitric oxide levels of serum in dogs infected with Babesia vogeli.
abstract: Oxidative stress was defined as corruption of balance between oxidant-antioxidant states in favor of oxidants. In this study, it was aimed to determine oxidative stress in naturally infected dogs with Babesia vogeli. The 8-hydroxy-2'-deoxyguanosine (8-OHdG), nitric oxide (NO) and total antioxidant capacity (TAC) levels in the sera were analyzed by ELISA. 8-OHdG levels increased in B. vogeli infected dogs compared to control group (P<0.05). Also, NO levels increased while TOC levels decreased in B. vogeli infected dogs but these variations were not found as statistically important (P>0.05).
authors.affiliation: Department of Biochemistry, Faculty of Veterinary Medicine, University of Ondokuz Mayis, 55200 Atakum, Samsun, Turkey. Electronic address: gciftci@omu.edu.tr.
authors.forename: Gulay
authors.initials: G
authors.lastname: Ciftci
authors.affiliation: Department of Internal Medicine, Faculty of Veterinary Medicine, University of Adnan Menderes, 09016 Işıklı, Aydın, Turkey.
authors.forename: Kerem
authors.initials: K
authors.lastname: Ural
authors.affiliation: Department of Parasitology, Faculty of Veterinary Medicine, University of Adnan Menderes, 09016 Işıklı, Aydın, Turkey.
authors.forename: Nuran
authors.initials: N
authors.lastname: Aysul
authors.affiliation: Department of Biochemistry, Faculty of Veterinary Medicine, University of Ondokuz Mayis, 55200 Atakum, Samsun, Turkey.
authors.forename: Sena
authors.initials: S
authors.lastname: Cenesiz
authors.affiliation: Department of Internal Medicine, Faculty of Veterinary Medicine, University of Ondokuz Mayis, 55200 Atakum, Samsun, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Guzel
authors.affiliation: Department of Internal Medicine, Faculty of Veterinary Medicine, University of Ondokuz Mayis, 55200 Atakum, Samsun, Turkey.
authors.forename: Didem
authors.initials: D
authors.lastname: Pekmezci
authors.affiliation: High School of Health, University of Ondokuz Mayis, 55200 Atakum, Samsun, Turkey.
authors.forename: Mehtap Ünlü
authors.initials: MÜ
authors.lastname: Sogut
mesh_terms: D000080242:8-Hydroxy-2'-Deoxyguanosine; D000818:Animals; D000975:Antioxidants / Q000032:analysis*; D001403:Babesia / Q000502:physiology*; D001404:Babesiosis / Q000378:metabolism*; D016054:DNA, Protozoan / Q000235:genetics; D003849:Deoxyguanosine / Q000031:analogs & derivatives* / Q000097:blood; D004283:Dog Diseases / Q000378:metabolism*; D004285:Dogs; D009569:Nitric Oxide / Q000097:blood*; D018384:Oxidative Stress
chemical_list: D000975:Antioxidants; D016054:DNA, Protozoan; D009569:Nitric Oxide; D000080242:8-Hydroxy-2'-Deoxyguanosine; D003849:Deoxyguanosine
keywords: 8-Hydroxy-2′-deoxyguanosine; Babesia vogeli; Nitric oxide; Oxidative stress; Total antioxidant capacity