title: [Bronchopulmonary ACTH-producing tumors].
abstract: Neuroendocrine tumors have the ability to produce the hormones and vasoactive peptides. Excess of these hormones leads to different symptoms and syndromes because of organs' injuries. Detection of ACTH origin by using of modern diagnostic methods is not always possible. Lungs and bronchi are one of the most frequent localization of ACTH-producing tumors. It is considered that carcinoids with bronchopulmonary localization like a benign tumors in the clinical course. But at the same time carcinoid tends to metastasize, so timely diagnostics and treatment improve quality of life significant and increase the life expectancy of patients. The modern state of diagnostics and surgical treatment problem of ACTH-producing tumors with bronchopulmonary localization is presented in the article. It was described the brief historical background, clinical symptoms, instrumental and biochemical methods of diagnosis. The principles of surgical treatment are presented in the article.
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Pikunov
authors.forename: N S
authors.initials: NS
authors.lastname: Kuznetsov
authors.forename: N V
authors.initials: NV
authors.lastname: Latkina
authors.forename: E A
authors.initials: EA
authors.lastname: Dobreva
authors.forename: O V
authors.initials: OV
authors.lastname: Remizov
mesh_terms: D000182:ACTH Syndrome, Ectopic / Q000097:blood / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D000293:Adolescent; D000324:Adrenocorticotropic Hormone / Q000097:blood*; D000328:Adult; D000465:Algorithms; D001984:Bronchial Neoplasms / Q000097:blood / Q000150:complications / Q000473:pathology / Q000601:surgery; D003907:Dexamethasone; D055088:Early Detection of Cancer; D061345:Early Medical Intervention; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood / Q000150:complications / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods; D018358:Neuroendocrine Tumors / Q000097:blood / Q000150:complications / Q000473:pathology / Q000601:surgery; D011013:Pneumonectomy / Q000379:methods / Q000523:psychology; D011379:Prognosis; D011788:Quality of Life; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D003907:Dexamethasone; D000324:Adrenocorticotropic Hormone