title: New CODIS core loci allele frequencies for 96,400 Brazilian individuals.
abstract: We have reported the allele frequencies of 15 STR loci, including the original 13 CODIS core loci, in over 100,000 Brazilian individuals. A new CODIS core loci has been proposed, but the recently established Brazilian Integrated Network of DNA Databases made a decision in 2010 to postpone the implementation of this new set of loci due to the lack of allele frequency data for the Brazilian population. We aimed to report allele frequencies of 20 loci, estimated from 96,400 Brazilian individuals undergoing paternity testing during 2011-2013. The percentage of missing data was less than 0.6% for all loci, except for CSF1PO (3.15%) and D7S820 (2.5%). The dropout rates estimated by the MicroDrop software were 0.013 for CSF1PO, 0.000037 for D7S820 and less than 0.000001 for other loci. Small missing data percentages and dropout rates reflect the high quality of the data.
authors.affiliation: Núcleo de Genética Humana e Molecular, Departamento de Ciências Biológicas, Universidade Federal do Espírito Santo, Av. Marechal Campos 1468, 29043-900 Vitória ES, Brazil.
authors.forename: Vitor R C
authors.initials: VR
authors.lastname: Aguiar
authors.affiliation: Laboratório Hermes Pardini, Departamento de Genética Molecular, Avenida das Nações 2448 Portaria A, 32200-000 Vespasiano MG, Brazil.
authors.forename: Amanda M
authors.initials: AM
authors.lastname: de Castro
authors.affiliation: Laboratório Hermes Pardini, Departamento de Genética Molecular, Avenida das Nações 2448 Portaria A, 32200-000 Vespasiano MG, Brazil.
authors.forename: Vanessa C O
authors.initials: VC
authors.lastname: Almeida
authors.affiliation: Laboratório Hermes Pardini, Departamento de Genética Molecular, Avenida das Nações 2448 Portaria A, 32200-000 Vespasiano MG, Brazil.
authors.forename: Frederico S V
authors.initials: FS
authors.lastname: Malta
authors.affiliation: Laboratório Hermes Pardini, Departamento de Genética Molecular, Avenida das Nações 2448 Portaria A, 32200-000 Vespasiano MG, Brazil.
authors.forename: Alessandro C S
authors.initials: AC
authors.lastname: Ferreira
authors.affiliation: Núcleo de Genética Humana e Molecular, Departamento de Ciências Biológicas, Universidade Federal do Espírito Santo, Av. Marechal Campos 1468, 29043-900 Vitória ES, Brazil. Electronic address: iurilouro@yahoo.com.
authors.forename: Iúri D
authors.initials: ID
authors.lastname: Louro
mesh_terms: D001938:Brazil; D016172:DNA Fingerprinting; D030561:Databases, Nucleic Acid; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D018895:Microsatellite Repeats; D016133:Polymerase Chain Reaction
keywords: Brazilian population; New CODIS core; STR allele frequencies