title: Component costs of foodborne illness: a scoping review.
abstract: BACKGROUND
  Governments require high-quality scientific evidence to prioritize resource allocation and the cost-of-illness (COI) methodology is one technique used to estimate the economic burden of a disease. However, variable cost inventories make it difficult to interpret and compare costs across multiple studies.
  
  
  METHODS
  A scoping review was conducted to identify the component costs and the respective data sources used for estimating the cost of foodborne illnesses in a population. This review was accomplished by: (1) identifying the research question and relevant literature, (2) selecting the literature, (3) charting, collating, and summarizing the results. All pertinent data were extracted at the level of detail reported in a study, and the component cost and source data were subsequently grouped into themes.
  
  
  RESULTS
  Eighty-four studies were identified that described the cost of foodborne illness in humans. Most studies (80%) were published in the last two decades (1992-2012) in North America and Europe. The 10 most frequently estimated costs were due to illnesses caused by bacterial foodborne pathogens, with non-typhoidal Salmonella spp. being the most commonly studied. Forty studies described both individual (direct and indirect) and societal level costs. The direct individual level component costs most often included were hospital services, physician personnel, and drug costs. The most commonly reported indirect individual level component cost was productivity losses due to sick leave from work. Prior estimates published in the literature were the most commonly used source of component cost data. Data sources were not provided or specifically linked to component costs in several studies.
  
  
  CONCLUSIONS
  The results illustrated a highly variable depth and breadth of individual and societal level component costs, and a wide range of data sources being used. This scoping review can be used as evidence that there is a lack of standardization in cost inventories in the cost of foodborne illness literature, and to promote greater transparency and detail of data source reporting. By conforming to a more standardized cost inventory, and by reporting data sources in more detail, there will be an increase in cost of foodborne illness research that can be interpreted and compared in a meaningful way.
authors.affiliation: Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada. taylor.mclinden@mail.mcgill.ca.
authors.forename: Taylor
authors.initials: T
authors.lastname: McLinden
authors.forename: Jan M
authors.initials: JM
authors.lastname: Sargeant
authors.forename: M Kate
authors.initials: MK
authors.lastname: Thomas
authors.forename: Andrew
authors.initials: A
authors.lastname: Papadopoulos
authors.forename: Aamir
authors.initials: A
authors.lastname: Fazil
mesh_terms: D017281:Cost of Illness; D005060:Europe; D005516:Food Microbiology; D005517:Foodborne Diseases / Q000191:economics* / Q000628:therapy; D017048:Health Care Costs / Q000639:trends*; D006801:Humans; D009656:North America