title: Dual responsiveness of a tunable thermo-sensitive polypeptide.
abstract: The temperature and pH dependent solubility of poly(γ-propargyl L-glutamate) (PPLG) functionalized through copper catalyzed 1,3 cycloaddition reaction between an alkyne and azide can be tuned with precision over a broad range of conditions by varying the ratio of substitution of short oligo ethylene glycol and diisopropylamine side groups.
authors.affiliation: Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139.
authors.forename: Caroline M
authors.initials: CM
authors.lastname: Chopko
authors.affiliation: Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139.
authors.forename: Erika L
authors.initials: EL
authors.lastname: Lowden
authors.affiliation: Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139.
authors.forename: Amanda C
authors.initials: AC
authors.lastname: Engler
authors.affiliation: Department of Biological Engineering, Department of Mechanical Engineering, and Center for Gynepathology Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
authors.forename: Linda G
authors.initials: LG
authors.lastname: Griffith
authors.affiliation: Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139.
authors.forename: Paula T
authors.initials: PT
authors.lastname: Hammond