title: A rare case of limbic encephalitis with anti leucine-rich glioma inactivated-1 (LGI1) antibodies.
abstract: We report a case of limbic encephalitis with LGI1 antibodies and cranial MRI abnormality. A 41-year-old woman who presented with confusional state that had started 1 month ago. Brain magnetic resonance imaging revealed hyperintense signal in right basal ganglia followed by hyperintense signals in left hippocampus and bilateral basal ganglia half a month later. This case expands the spectrum of limbic encephalitis to include LGI1 antibodies and cranial MRI changing process.
authors.affiliation: Department of Neurology, The First Teaching Hospital of Jilin University, Changchun, China.
authors.forename: Nannan
authors.initials: N
authors.lastname: Shen
authors.affiliation: Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
authors.forename: Haitao
authors.initials: H
authors.lastname: Ren
authors.affiliation: Department of Neurology, The First Teaching Hospital of Jilin University, Changchun, China.
authors.forename: Jiang
authors.initials: J
authors.lastname: Wu
authors.affiliation: Department of Neurology, The First Teaching Hospital of Jilin University, Changchun, China.
authors.forename: Jiachun
authors.initials: J
authors.lastname: Feng
authors.affiliation: Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
authors.forename: Liying
authors.initials: L
authors.lastname: Cui
authors.affiliation: Department of Neurology, The First Teaching Hospital of Jilin University, Changchun, China.
authors.forename: Shaokuan
authors.initials: S
authors.lastname: Fang
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000097:blood*; D005260:Female; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D020363:Limbic Encephalitis / Q000097:blood / Q000175:diagnosis* / Q000276:immunology*; D008279:Magnetic Resonance Imaging; D011506:Proteins / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D047908:Intracellular Signaling Peptides and Proteins; C116499:LGI1 protein, human; D011506:Proteins