title: Diffuse renal (18)F-FDG uptake of a patient with fever of unknown origin revealed sarcoidosis.
abstract: We report about the usefulness of F-FDG PET for the detection and therapy response evaluation of renal sarcoidosis. A 55-year-old woman presented with a condition diagnosed with pulmonary and ocular sarcoidosis 2 years before having anemia and acute deterioration of renal function. FDG PET revealed diffuse increased FDG uptake in both kidneys and the spleen. Histopathologic examination of a renal biopsy sample revealed granulomatous interstitial nephritis with sarcoidosis. After methylprednisolone treatment, the abnormal FDG uptake resolved completely with improvement of symptoms. FDG PET is a useful tool to detect active sarcoidosis regions and to monitor treatment efficacy.
authors.affiliation: From the Departments of *Nuclear Medicine, and †Internal Medicine II, Hokkaido University Graduate School of Medicine; and ‡Department of Pathology, KKR Sapporo Medical Center, Sapporo, Hokkaido, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Toyonaga
authors.forename: Osamu
authors.initials: O
authors.lastname: Manabe
authors.forename: Florian C
authors.initials: FC
authors.lastname: Gaertner
authors.forename: Tasuku
authors.initials: T
authors.lastname: Nakagaki
authors.forename: Saori
authors.initials: S
authors.lastname: Nishio
authors.forename: Akira
authors.initials: A
authors.lastname: Suzuki
authors.forename: Nagara
authors.initials: N
authors.lastname: Tamaki
mesh_terms: D001706:Biopsy; D005260:Female; D005335:Fever of Unknown Origin / Q000150:complications* / Q000000981:diagnostic imaging*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging* / Q000473:pathology; D008875:Middle Aged; D049268:Positron-Emission Tomography; D012507:Sarcoidosis / Q000150:complications* / Q000000981:diagnostic imaging*
chemical_list: D019788:Fluorodeoxyglucose F18