title: Effect of vaccination against foot-and-mouth disease on growth performance of Korean native goat (Capra hircus coreanae).
abstract: The objectives of this study were 1) to evaluate the effects of vaccination against foot-and-mouth disease (FMD) on growth performance, nutrient digestibility, hematological parameters, and behavior in a ruminant animal and 2) to investigate a possible strategy for reducing its adverse effect. A total of 12 Korean native goats (Capra hircus coreanae; 19.8 ± 2.9 kg) were used in a crossover design with 3 experimental periods and 3 treatments, randomized and balanced for counteracting possible carry-over effects. The treatments were 1) control, 2) co-injection with a commercially available dipyrone (CADI), and 3) supplementation with γ-amino butyric acid (GABA) at 10 g/kg in concentrate mix. Each period lasted 4 wk, and the vaccination against FMD was performed at 2 wk after the start of each period. The goats were individually housed in a metabolic cage and fed ad libitum with a diet consisting of bermuda grass and commercial concentrate mix (6:4, wt/wt). Dry matter intake, ADG, nutrients digestibility, hematological parameters, and behavioral activities of the goats were measured before and after vaccination. Although DMI was not decreased (P > 0.05), ADG was decreased by the vaccination to the goats (P < 0.01). The total number of leukocytes was increased while that of erythrocytes was decreased by the FMD vaccination (P < 0.01). The vaccination shortened standing time while extended lying time and the time spent in drinking (P < 0.05). The treatment by CADI reduced the adverse effect of vaccination on ADG and goat behavior compared with control and GABA treatment (P < 0.05). We concluded that the FMD vaccination decreased ADG of the goats without depression of diet intake, and CADI may attenuate the adverse effect of the FMD vaccination.
authors.affiliation: Department of Animal Biosystem Sciences, Chungnam National University, Daejeon 305-764, Republic of Korea.
authors.forename: N C
authors.initials: NC
authors.lastname: Jo
authors.affiliation: Department of Animal Biosystem Sciences, Chungnam National University, Daejeon 305-764, Republic of Korea.
authors.forename: J
authors.initials: J
authors.lastname: Jung
authors.affiliation: Department of Animal Biosystem Sciences, Chungnam National University, Daejeon 305-764, Republic of Korea.
authors.forename: J N
authors.initials: JN
authors.lastname: Kim
authors.affiliation: Department of Animal Biosystem Sciences, Chungnam National University, Daejeon 305-764, Republic of Korea.
authors.forename: J
authors.initials: J
authors.lastname: Lee
authors.affiliation: Department of Animal Biosystem Sciences, Chungnam National University, Daejeon 305-764, Republic of Korea.
authors.forename: S Y
authors.initials: SY
authors.lastname: Jeong
authors.affiliation: Department of Animal Biosystem Sciences, Chungnam National University, Daejeon 305-764, Republic of Korea.
authors.forename: W
authors.initials: W
authors.lastname: Kim
authors.affiliation: Department of Animal Science and Technology, Sangji University, Wonju, Gangwon 220-702, Republic of Korea.
authors.forename: H G
authors.initials: HG
authors.lastname: Sung
authors.affiliation: Department of Animal Biosystem Sciences, Chungnam National University, Daejeon 305-764, Republic of Korea swseo@cnu.kr.
authors.forename: S
authors.initials: S
authors.lastname: Seo
mesh_terms: D000818:Animals; D001522:Behavior, Animal; D019587:Dietary Supplements; D005536:Foot-and-Mouth Disease / Q000517:prevention & control*; D005765:Gastrointestinal Agents; D015511:Goat Diseases / Q000517:prevention & control*; D006041:Goats; D056910:Republic of Korea; D014611:Vaccination; D014765:Viral Vaccines / Q000009:adverse effects / Q000276:immunology*; D015430:Weight Gain
chemical_list: D005765:Gastrointestinal Agents; D014765:Viral Vaccines
keywords: Korean native goat (Capra hircus coreanae); foot-and-mouth disease; stress attenuation