title: Incidence of amlodipine-induced gingival overgrowth in the rural population of Loni.
abstract: OBJECTIVE
  Since the incidence of gingival overgrowth induced by amlodipine remains poorly defined, this study was carried out with an aim to determine the incidence.
  
  
  METHODS
  Dental patients who received amlodipine (N = 115), for more than 3 months were studied to determine the drug-induced gingival overgrowth. Clinical diagnosis of drug-induced overgrowth was verified by disappearance or decreased severity of gingival overgrowth after withdrawal of the causative drug.
  
  
  RESULTS
  The prevalence rate of amlodipine-induced gingival hyperplasia among experimental patients was 3.4%, while it was not observed among the control subjects. Oral examination revealed gingival overgrowth as a lobular or nodular enlargement on interdental papilla located in the anterior interproximal regions.
  
  
  CONCLUSIONS
  In this study, there was a significant relationship between gingival inflammation resulting from dental plaque and drug dosage, and hyperplasia.
authors.affiliation: GSBS Medical Trust, Loni, Maharashtra, India.
authors.forename: Avneesh
authors.initials: A
authors.lastname: Tejnani
authors.affiliation: Department of Periodontology, Rural Dental College, Loni, India.
authors.forename: Ameet
authors.initials: A
authors.lastname: Mani
authors.affiliation: Private Practitioner, Loni, Maharashtra, India.
authors.forename: Neha Kaur
authors.initials: NK
authors.lastname: Sodhi
authors.affiliation: Department of Periodontology, Hiranandani Hospital, Thane, Maharashtra, India.
authors.forename: Alok
authors.initials: A
authors.lastname: Mehta
authors.affiliation: Department of Periodontology, Late Shri Yashwantrao Chavan Memorial Medical and Rural Development Foundation's Dental College, Maharashtra, India.
authors.forename: Sonal
authors.initials: S
authors.lastname: Gourkhede
authors.affiliation: Department of Periodontology, BVP Dental College, Navi Mumbai, Maharashtra, India.
authors.forename: Vinayak
authors.initials: V
authors.lastname: Thorat
authors.affiliation: Department of Periodontology, Rural Dental College, Loni, India.
authors.forename: Pramod
authors.initials: P
authors.lastname: Marawar
keywords: Gingival hyperplasia; gingival overgrowth induced by amlodipine; hyperplasia