title: Malignant renal epithelioid angiomyolipoma with liver metastasis after resection: a case report with multimodality imaging and review of the literature.
abstract: Renal epithelioid angiomyolipoma (EAML) is a perivascular epithelioid cell tumor. Although the overwhelming majority of renal EAMLs are benign, cases of aggressive behavior and malignancy have been reported. Here, we report the case of a 62-year-old woman with a 12.5-cm renal EAML, who underwent resection and developed a 10.5-cm hepatic EAML 15 months after the surgery. Although multicentric disease is a possibility, the temporal course is consistent with metastasis from the poorly differentiated primary tumor. This is the only report with multimodality imaging to detail new metastatic disease during surveillance after intended curative resection of an EAML.
authors.affiliation: From the Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX.
authors.forename: Rafael A
authors.initials: RA
authors.lastname: Vicens
authors.forename: Corey T
authors.initials: CT
authors.lastname: Jensen
authors.forename: Brinda Rao
authors.initials: BR
authors.lastname: Korivi
authors.forename: Priya R
authors.initials: PR
authors.lastname: Bhosale
mesh_terms: D018207:Angiomyolipoma / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D000970:Antineoplastic Agents / Q000627:therapeutic use; D000068338:Everolimus; D005260:Female; D019788:Fluorodeoxyglucose F18; D005500:Follow-Up Studies; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging / Q000601:surgery; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery*; D008099:Liver / Q000000981:diagnostic imaging / Q000601:surgery; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D008875:Middle Aged; D064847:Multimodal Imaging / Q000379:methods*; D020360:Neoadjuvant Therapy / Q000379:methods; D049268:Positron-Emission Tomography / Q000379:methods; D019275:Radiopharmaceuticals; D020123:Sirolimus / Q000031:analogs & derivatives / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D000970:Antineoplastic Agents; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D000068338:Everolimus; D020123:Sirolimus