title: Long-term seizure outcome after stereotactic amygdalohippocampectomy.
abstract: BACKGROUND
  The aim of the study was to evaluate the long-term seizure outcome and complications after stereotactic radiofrequency amygdalohippocampectomy (SAHE) performed for mesial temporal lobe epilepsy (MTLE).
  
  
  METHODS
  The article describes the cases of 61 patients who were treated at our institution during the period 2004-2010. Mean post-operative follow-up was 5.3 years.
  
  
  RESULTS
  At the last postsurgical visit, 43 (70.5 %) patients were Engel Class I, six (9.8 %) Class II, nine (14.8 %) Class III and three (4.9 %) Class IV. The surgery was complicated by four intracranial haematomas. One of them caused acute hydrocephalus and was treated by shunting and resolved without sequelae. After SAHE, we performed open epilepsy surgery and re-thermo lesions in three and two patients, respectively (8.2 %). There were two cases of meningitis which required antibiotic treatment. In six patients psychiatric disorders developed and one of these committed suicide due to postoperative depression.
  
  
  CONCLUSIONS
  Our results provide preliminary evidence for good long-term seizure outcomes after SAHE. SAHE could be an alternative therapy for MTLE.
authors.affiliation: Department of Neurology, Na Homolce Hospital, Roentgenova 2, 150 30 5 - Motol, Prague, Czech Republic, zdenek.vojtech@homolka.cz.
authors.forename: Zdeněk
authors.initials: Z
authors.lastname: Vojtěch
authors.forename: Hana
authors.initials: H
authors.lastname: Malíková
authors.forename: Lenka
authors.initials: L
authors.lastname: Krámská
authors.forename: Jiří
authors.initials: J
authors.lastname: Anýž
authors.forename: Martin
authors.initials: M
authors.lastname: Syrůček
authors.forename: Josef
authors.initials: J
authors.lastname: Zámečník
authors.forename: Roman
authors.initials: R
authors.lastname: Liščák
authors.forename: Vilibald
authors.initials: V
authors.lastname: Vladyka
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000679:Amygdala / Q000601:surgery*; D004833:Epilepsy, Temporal Lobe / Q000601:surgery*; D005260:Female; D006624:Hippocampus / Q000601:surgery*; D006801:Humans; D021621:Imaging, Three-Dimensional; D020300:Intracranial Hemorrhages / Q000209:etiology; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000009:adverse effects; D011184:Postoperative Period; D012189:Retrospective Studies; D012640:Seizures / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult