title: Hemoglobins in the genome of the cryptomonad Guillardia theta.
abstract: Cryptomonads, are a lineage of unicellular and mostly photosynthetic algae, that acquired their plastids through the "secondary" endosymbiosis of a red alga - and still retain the nuclear genome (nucleomorph) of the latter. We find that the genome of the cryptomonad Guillardia theta comprises genes coding for 13 globin domains, of which 6 occur within two large chimeric proteins. All the sequences adhere to the vertebrate 3/3 myoglobin fold. Although several globins have no introns, the remainder have atypical intron locations. Bayesian phylogenetic analyses suggest that the G. theta Hbs are related to the stramenopile and chlorophyte single domain globins.
authors.forename: David R
authors.initials: DR
authors.lastname: Smith
authors.forename: Serge N
authors.initials: SN
authors.lastname: Vinogradov
authors.affiliation: Institute of Physiology and Zürich, Center for Integrative Human Physiology, University of Zürich, Winterthurerstrasse 190, Zürich CH-8057, Switzerland. david.hoogewijs@access.uzh.ch.
authors.forename: David
authors.initials: D
authors.lastname: Hoogewijs
mesh_terms: D000595:Amino Acid Sequence; D001499:Bayes Theorem; D002467:Cell Nucleus / Q000235:genetics / Q000378:metabolism; D044785:Cryptophyta / Q000145:classification / Q000235:genetics* / Q000378:metabolism; D006454:Hemoglobins / Q000145:classification / Q000235:genetics* / Q000378:metabolism; D010802:Phylogeny; D018087:Plastids / Q000235:genetics / Q000378:metabolism; D016415:Sequence Alignment
chemical_list: D006454:Hemoglobins