title: Ceftriaxone-induced hemolytic anemia: case report and review of literature.
abstract: Ceftriaxone is a frequently used empiric antibiotic in children. Acute hemolysis is a rare side effect of ceftriaxone therapy associated with a high mortality rate. A 14-year-old boy suffering from Crohn disease developed bacterial pneumonia that was treated with ceftriaxone. We report successful management of ceftriaxone-induced hemolytic anemia (CIHA) in this patient and review the CIHA literature in pediatric patients. Early recognition of CIHA with prompt discontinuation of ceftriaxone therapy may have a beneficial role in reduction of high mortality seen in these patients.
authors.affiliation: Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN.
authors.forename: Michael S
authors.initials: MS
authors.lastname: Northrop
authors.forename: Hemant S
authors.initials: HS
authors.lastname: Agarwal
mesh_terms: D000293:Adolescent; D000743:Anemia, Hemolytic / Q000139:chemically induced* / Q000628:therapy; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D002443:Ceftriaxone / Q000009:adverse effects*; D006801:Humans; D008297:Male
chemical_list: D000900:Anti-Bacterial Agents; D002443:Ceftriaxone