title: Species-specific bioaccumulation of halogenated organic pollutants and their metabolites in fish serum from an e-waste site, South China.
abstract: Halogenated organic pollutants (HOPs)-including organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), polybrominated diphenylethers (PBDEs), polybromobiphenyls (PBBs), dechlorane plus (DP), tetrabromobisphenol A (TBBPA), and hexabromocyclododecanes (HBCDs) as well as PCB metabolites (methylsulfone [MeSO2-]) and hydroxylated (OH-) PCBs and OH-PBDEs-were determined in the serum of mud carp and northern snakehead from an electronic-waste (e-waste) site in South China. The average concentrations (mean ± SD) of ΣPCBs, ΣPBDEs, ΣOCPs, ΣPBBs, ΣTBBPA, ΣHBCDs, and ΣDP were 1410 ± 324, 70 ± 20, 3.0 ± 0.4, 2.8 ± 0.8, 1.6 ± 0.4, 1.0 ± 0.2, and 0.3 ± 0.03 ng/g wet weight (ww) in mud carp and 6430 ± 781, 468 ± 49, 22.4 ± 1.1, 7.0 ± 0.6, 2.9 ± 2.3, 5.5 ± 1.1, and 4.6 ± 0.6 ng/g ww in northern snakehead, respectively. MeSO2-PCBs, OH-PCBs, and OH-PBDEs were detected at a total concentration of 0.44 ± 0.03 and 9.7 ± 0.3 ng/g ww in mud carp and northern snakehead, respectively. The congener profiles of PCBs, PBDEs, OH/MeSO2-PCBs, and OH-PBDEs were found to be significantly different between the two fish species, possibly as a result of species-specific bioaccumulation and/or metabolism of the HOPs. Chirality of ten PCB congeners and α-HBCD, as well as the f anti values of DP in the serum samples, supported the species-specific biotransformation of HOPs. Furthermore, the presence of covaried and counter-varied enantiomeric fractions of PCBs between the two fish species indicated species- and congener-specific enantiomer enrichment of PCBs.
authors.affiliation: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, 510640, China.
authors.forename: Yan-Hong
authors.initials: YH
authors.lastname: Zeng
authors.forename: Xiao-Jun
authors.initials: XJ
authors.lastname: Luo
authors.forename: Xiao-Bo
authors.initials: XB
authors.lastname: Zheng
authors.forename: Bin
authors.initials: B
authors.lastname: Tang
authors.forename: Jiang-Ping
authors.initials: JP
authors.lastname: Wu
authors.forename: Bi-Xian
authors.initials: BX
authors.lastname: Mai
mesh_terms: D000818:Animals; D002681:China; D059029:Electronic Waste; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000378:metabolism; D005399:Fishes / Q000097:blood* / Q000378:metabolism; D055768:Halogenated Diphenyl Ethers / Q000378:metabolism; D006843:Hydrocarbons, Chlorinated / Q000378:metabolism; D010575:Pesticides / Q000378:metabolism; D011078:Polychlorinated Biphenyls / Q000378:metabolism; D014874:Water Pollutants, Chemical / Q000097:blood* / Q000378:metabolism
chemical_list: D004785:Environmental Pollutants; D055768:Halogenated Diphenyl Ethers; D006843:Hydrocarbons, Chlorinated; D010575:Pesticides; D014874:Water Pollutants, Chemical; D011078:Polychlorinated Biphenyls