title: Scheimpflug imaging for long-term evaluation of optical components in Hungarian children with a history of preterm birth.
abstract: OBJECTIVE
  To determine ocular geometry and refraction in children with a history of preterm birth, and compare them to age-matched full-term children.
  
  
  METHODS
  In a prospective case-control study, 50 eyes of 27 premature patients 7 to 14 years of age were evaluated with Scheimpflug camera after cycloplegia. Age-matched full-term children comprised the control group (68 eyes of 34 children). All of the eligible eyes had a normal-appearing posterior pole. Anterior segment parameters such as keratometry, anterior chamber volume or thickness, and lens thickness were measured. Corneal thickness, lower- and higher-order aberrations refractive errors of the cornea (root mean square of lower- and higher-order aberrations: RMS LOA, RMS HOA) were also assessed and exported for further analysis.
  
  
  RESULTS
  In the premature eyes, anterior chamber depth was marginally smaller (P = .06), the lens was significantly thicker (P = .03), and axial length was significantly shorter (P < .001). Scheimpflug imaging showed a significant difference in corneal RMS (P = .03) and an increase in corneal RMS HOA (P = .002) in the premature group. Preterm birth showed significant impact on axial length (P < .01) and lens thickness (P = .05); at the same time, anterior chamber depth was more influenced by retinopathy of prematurity stage (P = .01). Laser treatment showed marginally significant impact (P = .06) on anterior chamber depth.
  
  
  CONCLUSIONS
  In premature eyes with or without mild retinopathy of prematurity, anterior segment anatomy is slightly different and they have more higher-order corneal aberrations compared to the eyes of term-born children.
authors.forename: Mónika
authors.initials: M
authors.lastname: Ecsedy
authors.forename: Illes
authors.initials: I
authors.lastname: Kovacs
authors.forename: Kata
authors.initials: K
authors.lastname: Mihaltz
authors.forename: Zsuzsa
authors.initials: Z
authors.lastname: Recsan
authors.forename: Andrea
authors.initials: A
authors.lastname: Szigeti
authors.forename: Eva
authors.initials: E
authors.lastname: Juhasz
authors.forename: Janos
authors.initials: J
authors.lastname: Nemeth
authors.forename: Zoltan Z
authors.initials: ZZ
authors.lastname: Nagy
mesh_terms: D000293:Adolescent; D000869:Anterior Eye Segment / Q000473:pathology*; D058452:Axial Length, Eye / Q000473:pathology*; D016022:Case-Control Studies; D002648:Child; D057108:Corneal Wavefront Aberration / Q000175:diagnosis*; D003941:Diagnostic Techniques, Ophthalmological; D005865:Gestational Age; D006801:Humans; D006814:Hungary; D010781:Photography / Q000295:instrumentation*; D047928:Premature Birth / Q000473:pathology*; D011446:Prospective Studies; D012178:Retinopathy of Prematurity / Q000175:diagnosis*; D047929:Term Birth; D014792:Visual Acuity