title: Cross sections of deuteron induced reactions on (nat)Sm for production of the therapeutic radionuclide ¹⁴⁵Sm and ¹⁵³Sm.
abstract: At present, targeted radiotherapy (TR) is acknowledged to have great potential in oncology. A large list of interesting radionuclides is identified, including several radioisotopes of lanthanides, amongst them (145)Sm and (153)Sm. In this work the possibility of their production at a cyclotron was investigated using a deuteron beam and a samarium target. The excitation functions of the (nat)Sm(d,x)(145,153)Sm reactions were determined for deuteron energies up to 50 MeV using the stacked-foil technique and high-resolution γ-ray spectrometry. The measured cross sections and the contributing reactions were analyzed by comparison with results of the ALICE, EMPIRE and TALYS nuclear reaction codes. A short overview and comparison of possible production routes is given.
authors.affiliation: Institute for Nuclear Research of the Hungarian Academy of Sciences (ATOMKI), 4026 Debrecen, Hungary.
authors.forename: F
authors.initials: F
authors.lastname: Tárkányi
authors.affiliation: Cyclotron Laboratory, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, 1090 Brussels, Belgium.
authors.forename: A
authors.initials: A
authors.lastname: Hermanne
authors.affiliation: Institute for Nuclear Research of the Hungarian Academy of Sciences (ATOMKI), 4026 Debrecen, Hungary.
authors.forename: S
authors.initials: S
authors.lastname: Takács
authors.affiliation: Institute for Nuclear Research of the Hungarian Academy of Sciences (ATOMKI), 4026 Debrecen, Hungary. Electronic address: ditroi@atomki.hu.
authors.forename: F
authors.initials: F
authors.lastname: Ditrói
authors.affiliation: Institute for Nuclear Research of the Hungarian Academy of Sciences (ATOMKI), 4026 Debrecen, Hungary.
authors.forename: J
authors.initials: J
authors.lastname: Csikai
authors.affiliation: Institute of Physics and Power Engineering (IPPE), Obninsk 249020, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Ignatyuk
mesh_terms: D003903:Deuterium / Q000737:chemistry*; D011868:Radioisotopes / Q000737:chemistry*; D019275:Radiopharmaceuticals / Q000138:chemical synthesis* / Q000737:chemistry; D012493:Samarium / Q000737:chemistry*
chemical_list: D011868:Radioisotopes; D019275:Radiopharmaceuticals; D012493:Samarium; D003903:Deuterium
keywords: (145)Sm; (153)Sm; Deuteron irradiation; Natural samarium target; Physical yield