title: Impaired corneal biomechanical properties and the prevalence of keratoconus in mitral valve prolapse.
abstract: Objective. To investigate the biomechanical characteristics of the cornea in patients with mitral valve prolapse (MVP) and the prevalence of keratoconus (KC) in MVP. Materials and Methods. Fifty-two patients with MVP, 39 patients with KC, and 45 control individuals were recruited in this study. All the participants underwent ophthalmologic examination, corneal analysis with the Sirius system (CSO), and the corneal biomechanical evaluation with Reichert ocular response analyzer (ORA). Results. KC was found in six eyes of four patients (5.7%) and suspect KC in eight eyes of five patients (7.7%) in the MVP group. KC was found in one eye of one patient (1.1%) in the control group (P = 0.035). A significant difference occurred in the mean CH and CRF between the MVP and control groups (P = 0.006 and P = 0.009, resp.). All corneal biomechanical and topographical parameters except IOPcc were significantly different between the KC-MVP groups (P < 0.05). Conclusions. KC prevalence is higher than control individuals in MVP patients and the biomechanical properties of the cornea are altered in patients with MVP. These findings should be considered when the MVP patients are evaluated before refractive surgery.
authors.affiliation: Department of Ophthalmology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, Turkey.
authors.forename: Emine
authors.initials: E
authors.lastname: Kalkan Akcay
authors.affiliation: Department of Cardiology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Akcay
authors.affiliation: Department of Ophthalmology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, Turkey.
authors.forename: Betul Seher
authors.initials: BS
authors.lastname: Uysal
authors.affiliation: Department of Ophthalmology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, Turkey.
authors.forename: Pinar
authors.initials: P
authors.lastname: Kosekahya
authors.affiliation: Department of Cardiology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, Turkey.
authors.forename: Abdullah Nabi
authors.initials: AN
authors.lastname: Aslan
authors.affiliation: Department of Ophthalmology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, Turkey.
authors.forename: Mehtap
authors.initials: M
authors.lastname: Caglayan
authors.affiliation: Department of Cardiology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, Turkey.
authors.forename: Cemal
authors.initials: C
authors.lastname: Koseoglu
authors.affiliation: Department of Ophthalmology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, Turkey.
authors.forename: Fatma
authors.initials: F
authors.lastname: Yulek
authors.affiliation: Department of Ophthalmology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, Turkey.
authors.forename: Nurullah
authors.identifier: 0000-0002-3845-066X
authors.initials: N
authors.lastname: Cagil