title: Can we use electrocochleography as a clinical tool in the diagnosis of Meniere's disease during the early symptomatic period?
abstract: CONCLUSIONS
  Our results indicate that electrocochleography (ECoG) has limited value in diagnosing Meniere's disease during the early symptomatic period.
  
  
  OBJECTIVE
  We hypothesized that if endolymphatic hydrops is a cause of Meniere's disease, ECoG results obtained in normal subjects would differ from those obtained during the early symptomatic period of Meniere's disease. We aimed to investigate the usefulness of ECoG in the diagnosis of Meniere's disease during the early symptomatic period.
  
  
  METHODS
  Extratympanic ECoG was used to evaluate 60 patients in a Meniere's group (17 men, 43 women; mean age 43.6 years, range 19-62 years) and 30 controls (11 men, 19 women; mean age 43.5 years, range 21-63 years). The summating potential/action potential (SP/AP) amplitude ratio and SP/AP area ratio were compared between the groups.
  
  
  RESULTS
  Statistically significant differences were not demonstrated in the SP/AP amplitude ratio between the definite Meniere's, probable Meniere's, overall Meniere's, or control groups (0.35 ± 0.02, 0.30 ± 0.03, 0.33 ± 0.02, and 0.30 ± 0.01, respectively). Additionally, statistically significant differences were not indicated in the mean SP/AP area ratio between the definite Meniere's, probable Meniere's, overall Meniere's, or control groups (5.18 ± 0.98, 4.78 ± 0.21, 4.01 ± 0.78, and 3.72 ± 0.66, respectively).
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery.
authors.forename: Kyoung Ho
authors.initials: KH
authors.lastname: Oh
authors.forename: Kang-Woo
authors.initials: KW
authors.lastname: Kim
authors.forename: Jiwon
authors.initials: J
authors.lastname: Chang
authors.forename: Hyun-Su
authors.initials: HS
authors.lastname: Jun
authors.forename: Eun Ha
authors.initials: EH
authors.lastname: Kwon
authors.forename: Jeong-Yoon
authors.initials: JY
authors.lastname: Choi
authors.forename: Gi Jung
authors.initials: GJ
authors.lastname: Im
authors.forename: Sung Won
authors.initials: SW
authors.lastname: Chae
authors.forename: Hak Hyun
authors.initials: HH
authors.lastname: Jung
authors.forename: June
authors.initials: J
authors.lastname: Choi
mesh_terms: D000328:Adult; D000368:Aged; D001300:Audiometry, Evoked Response / Q000379:methods*; D003937:Diagnosis, Differential; D042241:Early Diagnosis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000175:diagnosis* / Q000209:etiology; D008875:Middle Aged; D015203:Reproducibility of Results; D012189:Retrospective Studies; D013997:Time Factors; D055815:Young Adult
keywords: Endolymphatic hydrops; SP/AP; SP/AP area ratio; amplitude ratio; summating potential/action potential