title: [Comparison of TaperGuard tube and the Portex Softseal for prevention of vomitus leakage in an in vitro simulation airway model].
abstract: BACKGROUND
  Microaspiration of vomitus can cause a serious condition known as Mendelson's syndrome. The present study used simulated stomach contents and an airway model to compare a tracheal tube with a tapered cuff (Taper) to the conventional high volume low pressure cuff (HVLP) in their abilities to prevent microaspiration.
  
  
  METHODS
  The automated cuff pressure was adjusted to 10, 20, and 30 cmH2O. We poured 5 ml of simulated stomach contents above the cuff in the vertically situated airway model and measured the leakage volume after 5 minutes as well as 4 hours.
  
  
  RESULTS
  After 5 minutes, leakage volume was significantly lower for the Taper than for the HVLP at 10 cmH2O, but not for 20 and 30 cmH2O. After 4 hours, stomach content leakage was significantly less with the Taper than with the HVLP, regardless of cuff pressure (P < 0.05).
  
  
  CONCLUSIONS
  We conclude that the Taper may be more effective than the conventional HVLP in preventing vomitus microaspiration in an airway model simulation.
authors.forename: Sayuri
authors.initials: S
authors.lastname: Matsunami
authors.forename: Nobuyasu
authors.initials: N
authors.lastname: Komasawa
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Fujiwara
authors.forename: Kenta
authors.initials: K
authors.lastname: Nakao
authors.forename: Shinichi
authors.initials: S
authors.lastname: Tatsumi
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Minami
mesh_terms: D006801:Humans; D007442:Intubation, Intratracheal / Q000295:instrumentation*; D008953:Models, Anatomic; D053717:Pneumonia, Ventilator-Associated / Q000517:prevention & control*; D014839:Vomiting