title: Development of Frequency of Stools over Time in Children with Hirschsprung Disease Posttransanal Endorectal One-Stage Pull-through.
abstract: BACKGROUND
  The transanal endorectal one-stage pull-through (TERPT) procedure in children with Hirschsprung disease (HD) is frequently used worldwide. To give the children's families realistic expectations and to plan the medical care for the period after TERPT, the outcome is of great importance.
  
  
  OBJECTIVE
  The aim of this article is to collect information on the number of stools passed daily after one-stage TERPT procedure for HD. Patients and
  
  
  METHODS
  A prospective follow-up study for collecting information on the outcome of planned TERPT from 2005 through 2012 was performed. A control group consisting of age and gender matched children was used.
  
  
  RESULTS
  The results show an initial high frequency of daily stools, median 12 stools/day (range, 3-30 stools/day), reaching an acceptable situation with median 4 stools/day (range, 0-10 stools/day) after 1 year. After 4 years, the number of stools did not differ significantly from healthy controls.
  
  
  CONCLUSIONS
  This study shows that it takes 4 years after TERPT before the number of stools becomes normalized. To compare the long-term outcome, it would be desirable to have uniform regular reports on the daily frequency of passed stools, incontinence, and constipation during the years after TERPT.
authors.affiliation: Department of Pediatric Surgery, Skane University Hospital, Lund, Sweden.
authors.forename: Christina
authors.initials: C
authors.lastname: Granéli
authors.affiliation: Department of Pediatric Surgery, Skane University Hospital, Lund, Sweden.
authors.forename: Pernilla
authors.initials: P
authors.lastname: Stenström
authors.affiliation: Department of Pediatric Surgery, Skane University Hospital, Lund, Sweden.
authors.forename: Anna
authors.initials: A
authors.lastname: Börjesson
authors.affiliation: Department of Pediatric Surgery, Skane University Hospital, Lund, Sweden.
authors.forename: Einar
authors.initials: E
authors.lastname: Arnbjornsson
mesh_terms: D002648:Child; D002675:Child, Preschool; D003248:Constipation / Q000209:etiology; D003672:Defecation / Q000502:physiology*; D013505:Digestive System Surgical Procedures / Q000009:adverse effects; D005242:Fecal Incontinence / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006627:Hirschsprung Disease / Q000503:physiopathology* / Q000601:surgery*; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D016896:Treatment Outcome