title: Resource utilisation associated with single digit Dupuytren's contracture treated with either surgery or injection of collagenase Clostridium histolyticum.
abstract: The gold standard treatment for Dupuytren's contracture is surgical excision of the cord. A non-surgical treatment with collagenase clostridium histolyticum injection is available but appears costly.
  
  
  OBJECTIVE
  To provide data on resource consumption related to surgical and non-surgical treatment for Dupuytren's contracture.
  
  
  METHODS
  Twenty patients with a single digit Dupuytren's contracture, 10 treated with surgical excision, and 10 treated with a single injection of collagenase.
  
  
  METHODS
  Minutes spent in theatre, number of follow-up appointments, time to skin healing, and patients return to normal activities of daily living.
  
  
  RESULTS
  The injection group was significantly better regarding theatre time (p < 0.0001), follow-up appointments (p = 0.048), skin healing time (p < 0.001), and return to normal activities of daily living (p = 0.02) than the operated group.
  
  
  CONCLUSIONS
  There are significant personal and health economic differences between the two methods of treatment which may influence local choice.
authors.affiliation: Department of Orthopaedic Surgery, Guy's & St. Thomas' Hospital NHS Trust, London, SE1 9RT, UK.
authors.forename: Bo
authors.initials: B
authors.lastname: Povlsen
authors.forename: Adrian M
authors.initials: AM
authors.lastname: Shields
authors.forename: Gev S
authors.initials: GS
authors.lastname: Bhabra
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D000556:Ambulatory Surgical Procedures / Q000191:economics / Q000706:statistics & numerical data*; D017281:Cost of Illness; D004387:Dupuytren Contracture / Q000191:economics* / Q000628:therapy*; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D003012:Microbial Collagenase / Q000008:administration & dosage / Q000191:economics*; D008875:Middle Aged; D009313:National Health Programs; D009819:Office Visits / Q000191:economics / Q000706:statistics & numerical data; D020127:Recovery of Function; D062707:Return to Work; D013997:Time Factors; D006113:United Kingdom; D014945:Wound Healing
chemical_list: D003012:Microbial Collagenase