title: Optimizing the transfer of [¹⁸F]fluoride from aqueous to organic solvents by electrodeposition using carbon electrodes.
abstract: The effect of varying structural modifications of carbon anodes, ranging from thin layers of crystalline boron-doped diamond up to highly graphitic bulk materials, was systematically examined for the possibility of electrochemical fixation and desorption of no-carrier-added [(18)F]fluoride from an aqueous solution. Pyrolysed carbon, i.e. "glassy carbon" (Sigradur(®)G), proved as the most efficient material for deposition and release. An overall radiochemical yield of about 60% was achieved when using this for fixation and DMSO/ionic additive as organic solution for the release of [(18)F]fluoride.
authors.affiliation: Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.
authors.forename: Fabian
authors.initials: F
authors.lastname: Kügler
authors.affiliation: Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.
authors.forename: Daniel
authors.initials: D
authors.lastname: Roehrens
authors.affiliation: Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.
authors.forename: Milosch
authors.initials: M
authors.lastname: Stumpf
authors.affiliation: Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Drerup
authors.affiliation: Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany. Electronic address: j.ermert@fz-juelich.de.
authors.forename: Johannes
authors.initials: J
authors.lastname: Ermert
authors.affiliation: Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.
authors.forename: Kurt
authors.initials: K
authors.lastname: Hamacher
authors.affiliation: Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.
authors.forename: Heinz H
authors.initials: HH
authors.lastname: Coenen
keywords: Carbon electrodes; Electrodeposition; Intercalation; Micro fluidics; [(18)F]fluoride