title: [Economic efficiency of renal denervation in patients with resistant hypertension: results of Markov modeling].
abstract: Aim of this study was to evaluate the cost-effectiveness of renal denervation (RD) in resistant arterial hypertension (AH) in Russia. Modeling of Markov conducted economic impact of RD on the Russian population of patients with resistant hypertension in combination with optimal medical therapy (OMT) compared with OMT using a model developed by American researchers based on the results of international research. The model contains data on Russian mortality, and costs of major complications of hypertension. The simulation results showed a significant reduction in relative risk reduction of adverse outcomes in patients with resistant hypertension for 10 years (risk of stroke is reduced by 30%, myocardial infarction - 32%). RD saves 0.9 years of quality-adjusted life (QALY) by an average of 1 patient with resistant hypertension. Costs for 1 year stored in the application of quality of life amounted to RD 203 791.6 rubles. Which is below the 1 gross domestic product and therefore indicates the feasibility of this method in Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Kontsevaia
authors.forename: E I
authors.initials: EI
authors.lastname: Suvorova
authors.forename: M B
authors.initials: MB
authors.lastname: Khudiakov
mesh_terms: D003362:Cost-Benefit Analysis; D003714:Denervation / Q000191:economics* / Q000379:methods / Q000706:statistics & numerical data*; D006801:Humans; D006973:Hypertension / Q000601:surgery*; D007668:Kidney / Q000294:innervation* / Q000601:surgery*; D008390:Markov Chains; D015233:Models, Statistical