title: Hypercohones D-G, New Polycyclic Polyprenylated Acylphloroglucinol Type Natural Products from Hypericum cohaerens.
abstract: Four new polycyclic polyprenylated acylphloroglucinol type metabolites, hypercohones D-G (1-4), along with four known analogues (5-8), were isolated from the aerial parts of Hypericum cohaerens. The structures of these isolates were elucidated by extensive spectroscopic methods. The inhibitory activities of these isolates against five human cancer cell lines in vitro were also tested.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 People's Republic of China ; University of Chinese Academy of Sciences, Beijing, 100049 People's Republic of China.
authors.forename: Jing-Jing
authors.initials: JJ
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 People's Republic of China ; University of Chinese Academy of Sciences, Beijing, 100049 People's Republic of China.
authors.forename: Xing-Wei
authors.initials: XW
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 People's Republic of China.
authors.forename: Jun-Zeng
authors.initials: JZ
authors.lastname: Ma
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 People's Republic of China.
authors.forename: Xia
authors.initials: X
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 People's Republic of China.
authors.forename: Li-Xin
authors.initials: LX
authors.lastname: Yang
authors.affiliation: Institute of Chinese Medicinal Materials, Yunnan Agricultural University, Kunming, 650201 People's Republic of China.
authors.forename: Sheng-Chao
authors.initials: SC
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 People's Republic of China.
authors.forename: Gang
authors.initials: G
authors.lastname: Xu
keywords: Acylphloroglucinol; Guttiferae; Hypercohones D–G; Hypericum cohaerens