title: Inheritance is where physiology meets evolution.
abstract: Physiology and evolutionary biology have developed as two separated disciplines, a separation that mirrored the hypothesis that the physiological and evolutionary processes could be decoupled. We argue that non-genetic inheritance shatters the frontier between physiology and evolution, and leads to the coupling of physiological and evolutionary processes to a point where there exists a continuum between accommodation by phenotypic plasticity and adaptation by natural selection. This approach is also profoundly affecting the definition of the concept of phenotypic plasticity, which should now be envisaged as a multi-scale concept. We further suggest that inclusive inheritance provides a quantitative way to help bridging infra-individual (i.e. physiology) with supra-individual (i.e. evolution) approaches, in a way that should help building the long sough inclusive evolutionary synthesis.
authors.affiliation: CNRS, UPS, ENFA; EDB (Laboratoire Evolution & Diversité Biologique), UMR5174, 118 route de Narbonne, F-31062, Toulouse, France Université de Toulouse, UMR5174, F-31062, Toulouse, France etienne.danchin@univ-tlse3.fr.
authors.forename: Etienne
authors.initials: E
authors.lastname: Danchin
authors.affiliation: Center for Philosophy of Science, University of Pittsburgh, 817 Cathedral of Learning, Pittsburgh, PA, 15260, USA.
authors.forename: Arnaud
authors.initials: A
authors.lastname: Pocheville
mesh_terms: D000222:Adaptation, Physiological / Q000235:genetics*; D000818:Animals; D005075:Biological Evolution; D018507:Gene Expression Regulation, Developmental; D010829:Physiological Phenomena / Q000235:genetics*