title: [Management of complications related to intraduodenal infusion of levodopa/carbidopa in patients with Parkinson's disease].
abstract: Continuous infusion of intraduodenal levodopa/carbidopa is an effective treatment that improves the motor complications and the quality of life of patients in the advanced stages of Parkinson's disease. However, it is not free of complications. These may present in the post-operative period following surgery (gastrostomy) or in the long-term during the follow-up period and can be related with the medication (levodopa/carbidopa), the stoma, the gastrostomy or the device (pump, enteral tube, parts of the FREKA system). The aim of this review is to report on the management of the complications that can be observed in patients with advanced Parkinson's disease treated with continuous infusion of intraduodenal levodopa/carbidopa.
authors.affiliation: Complejo Hospitalario Arquitecto Marcide - Profesor Novoa Santos, 15405 El Ferrol, Espana.
authors.forename: Diego
authors.initials: D
authors.lastname: Santos-Garcia
authors.forename: Teresa
authors.initials: T
authors.lastname: de Deus
authors.forename: Elina
authors.initials: E
authors.lastname: Lopez-Pazos
authors.forename: Mercedes
authors.initials: M
authors.lastname: Macias-Arribi
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Llaneza-Gonzalez
authors.forename: Ana
authors.initials: A
authors.lastname: Echarri-Piudo
authors.forename: Pedro
authors.initials: P
authors.lastname: Carpintero
authors.forename: Raúl
authors.initials: R
authors.lastname: de la Fuente-Fernandez
mesh_terms: D000978:Antiparkinson Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D002230:Carbidopa / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D004386:Duodenum; D005767:Gastrointestinal Diseases / Q000139:chemically induced; D005774:Gastrostomy / Q000009:adverse effects*; D006099:Granuloma / Q000209:etiology / Q000628:therapy; D006801:Humans; D007260:Infusion Pumps / Q000009:adverse effects; D007263:Infusions, Parenteral; D007980:Levodopa / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D015337:Multicenter Studies as Topic; D064887:Observational Studies as Topic; D010146:Pain / Q000209:etiology; D010300:Parkinson Disease / Q000188:drug therapy*; D010538:Peritonitis / Q000209:etiology; D011183:Postoperative Complications / Q000209:etiology / Q000628:therapy*; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D012189:Retrospective Studies; D054047:Surgical Stomas / Q000009:adverse effects
chemical_list: D000978:Antiparkinson Agents; D007980:Levodopa; D002230:Carbidopa