title: Outcomes of trabeculectomy in microspherophakia.
abstract: OBJECTIVE
  To report the outcomes of trabeculectomy in eyes with glaucoma in microspherophakia.
  
  
  METHODS
  In a retrospective non-comparative case series, we analyzed 29 eyes of 18 patients with glaucoma in microspherophakia, who underwent primary trabeculectomy between 1998 and 2012. Success was defined as complete if the intraocular pressure (IOP) was ≤ 21 and > 5 mm Hg without any antiglaucoma medication and qualified if IOP ≤ 21 and >5 mm Hg with or without antiglaucoma medications. Eyes not falling into qualified success criteria were labeled as failure.
  
  
  RESULTS
  The median age at the time of trabeculectomy was 23 years (inter quartile range: 12, 28). The mean IOP reduced from 31.1 ± 8.6 mm Hg to 14.6 ± 4.4 mm Hg after trabeculectomy over a median follow up of 77 months (P < 0.001). The probability of complete success was 96% (95% CI: 77-99%) at one year, 88% (95% CI: 67-96%) at 2 years, which was maintained till 7 years and decreased to 79% (95% CI: 50-92%) at 8 years. The probability of qualified success was 100% till 7 years and decreased to 90% (95% CI: 47-98%) at 8 years. The median number of postoperative medications reduced from 2 to 0 postoperatively (P < 0.001) . Five eyes (21%) developed post-operative shallow anterior chamber (AC) requiring anterior chamber reformation, with 2 of these eyes needing lensectomy for resolution of this complication.
  
  
  CONCLUSIONS
  Primary trabeculectomy had good success rate in glaucoma associated with microspherophakia. Post-operative shallow AC was a frequent complication needing additional intervention.
authors.affiliation: VST Glaucoma Center, L V Prasad Eye Institute, Banjara Hills, Hyderabad, Andhra Pradesh, India.
authors.forename: Sirisha
authors.initials: S
authors.lastname: Senthil
authors.forename: Harsha L
authors.initials: HL
authors.lastname: Rao
authors.forename: Jonnadula G
authors.initials: JG
authors.lastname: Babu
authors.forename: Anil K
authors.initials: AK
authors.lastname: Mandal
authors.forename: Uday K
authors.initials: UK
authors.lastname: Addepalli
authors.forename: Chandra S
authors.initials: CS
authors.lastname: Garudadri
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003316:Corneal Diseases / Q000150:complications / Q000601:surgery*; D004479:Ectopia Lentis / Q000150:complications / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000150:complications / Q000601:surgery*; D005902:Glaucoma, Open-Angle / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D007429:Intraocular Pressure; D007498:Iris / Q000002:abnormalities* / Q000601:surgery; D008297:Male; D012189:Retrospective Studies; D014130:Trabeculectomy / Q000379:methods*; D016896:Treatment Outcome; D014792:Visual Acuity; D055815:Young Adult