title: Combined therapy of percutaneous cryoablation and traditional Chinese medicine can be a promising strategy for elderly or advanced lung cancer patients based on a retrospective clinical study.
abstract: Presently, elderly and advanced lung cancer patients have very limited treatment options. With no promising therapy, treatment of these patients is challenging. We have reviewed 119 primary lung cancer patients who received a combined percutaneous cryoablation and traditional Chinese medicine therapy (Cryo-TCM therapy) between 2005 and 2013. Out of 119 patients, 84.1% patients were elderly or advanced lung cancer when receiving cryoablation. Overall Survival time from the time of Diagnosis (DOS) and Cryoablation (COS) was 19 and 10 months respectively, which were longer than data previously published. Patients who accepted only Cryo-TCM therapy got similar DOS as those who were treated with Cryo-TCM and other classic anticancer therapies. Thus, Cryo-TCM therapy can prolong the survival time and can be used as the main therapy for the elderly or advanced lung cancer patients in China both in quality of life and cost effectiveness.
authors.affiliation: Oncology Department, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Gao
authors.affiliation: Oncology Department, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China.
authors.forename: Quanwang
authors.initials: Q
authors.lastname: Li
authors.affiliation: Oncology Department, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China.
authors.forename: Min
authors.initials: M
authors.lastname: Jiang
authors.affiliation: Oncology Department, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China.
authors.forename: Chuanbo
authors.initials: C
authors.lastname: Liu
authors.affiliation: Oncology Department, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China.
authors.forename: Zilin
authors.initials: Z
authors.lastname: Song
authors.affiliation: Oncology Department, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China.
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Bao
authors.affiliation: Oncology Department, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Shen
authors.affiliation: Laboratory Department, Guanganmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
authors.forename: Guijian
authors.initials: G
authors.lastname: Liu
authors.affiliation: Oncology Department, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China. Electronic address: kaiwenh@163.com.
authors.forename: Kaiwen
authors.initials: K
authors.lastname: Hu
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D003131:Combined Modality Therapy; D003452:Cryosurgery / Q000379:methods*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology / Q000601:surgery; D008175:Lung Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D008297:Male; D008516:Medicine, Chinese Traditional; D011788:Quality of Life; D012189:Retrospective Studies; D016896:Treatment Outcome
keywords: Cryoablation; Elderly; Lung cancer; Traditional Chinese medicine