title: A new approach based on Machine Learning for predicting corneal curvature (K1) and astigmatism in patients with keratoconus after intracorneal ring implantation.
abstract: Keratoconus (KC) is the most common type of corneal ectasia. A corneal transplantation was the treatment of choice until the last decade. However, intra-corneal ring implantation has become more and more common, and it is commonly used to treat KC thus avoiding a corneal transplantation. This work proposes a new approach based on Machine Learning to predict the vision gain of KC patients after ring implantation. That vision gain is assessed by means of the corneal curvature and the astigmatism. Different models were proposed; the best results were achieved by an artificial neural network based on the Multilayer Perceptron. The error provided by the best model was 0.97D of corneal curvature and 0.93D of astigmatism.
authors.affiliation: LabHuman, Universitat Politècnica de València, Camino de Vera s/n, 46022, Valencia, Spain(1).
authors.forename: M A
authors.initials: MA
authors.lastname: Valdés-Mas
authors.affiliation: Dpt. Enginyeria Electrònica, Universitat de València, Avgda. Universitat, s/n, 46100, Burjassot, Valencia, Spain(2).
authors.forename: J D
authors.initials: JD
authors.lastname: Martín-Guerrero
authors.affiliation: LabHuman, Universitat Politècnica de València, Camino de Vera s/n, 46022, Valencia, Spain(1). Electronic address: mjruperez@labhuman.i3bh.es.
authors.forename: M J
authors.initials: MJ
authors.lastname: Rupérez
authors.affiliation: Fundación Oftalmológica del Mediterráneo, Bifurcación Pío Baroja-General Avilés, s/n, 46015 Valencia, Spain(3).
authors.forename: F
authors.initials: F
authors.lastname: Pastor
authors.affiliation: Fundación Oftalmológica del Mediterráneo, Bifurcación Pío Baroja-General Avilés, s/n, 46015 Valencia, Spain(3).
authors.forename: C
authors.initials: C
authors.lastname: Dualde
authors.affiliation: LabHuman, Universitat Politècnica de València, Camino de Vera s/n, 46022, Valencia, Spain(1).
authors.forename: C
authors.initials: C
authors.lastname: Monserrat
authors.affiliation: Fundación Oftalmológica del Mediterráneo, Bifurcación Pío Baroja-General Avilés, s/n, 46015 Valencia, Spain(3).
authors.forename: C
authors.initials: C
authors.lastname: Peris-Martínez
mesh_terms: D000328:Adult; D000368:Aged; D001185:Artificial Intelligence; D001251:Astigmatism / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control; D019781:Corneal Topography / Q000379:methods; D016039:Corneal Transplantation / Q000009:adverse effects* / Q000379:methods; D020000:Decision Support Systems, Clinical; D005260:Female; D006801:Humans; D007640:Keratoconus / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D063868:Patient Outcome Assessment; D011379:Prognosis; D019736:Prostheses and Implants / Q000009:adverse effects*; D017755:Prosthesis Fitting / Q000379:methods*; D016896:Treatment Outcome; D055815:Young Adult
keywords: Astigmatism; Intracorneal rings; Keratoconus; Machine Learning