title: Sixth INTERMACS annual report: a 10,000-patient database.
abstract: The sixth annual report of the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) summarizes the first 8 years of patient enrollment. The analysis is based on data from >10,000 patients and updates demographics, survival, adverse events and risk factors. Among patients with continuous-flow pumps, actuarial survival continues to be 80% at 1 year and 70% at 2 years. The report features a comparison of two eras of continuous-flow durable devices in the USA in terms of device strategy, patient profiles, adverse event burden, survival and quality of life.
authors.affiliation: Department of Surgery, University of Alabama at Birmingham, Alabama. Electronic address: jkirklin@uab.edu.
authors.forename: James K
authors.initials: JK
authors.lastname: Kirklin
authors.affiliation: Department of Surgery, University of Alabama at Birmingham, Alabama.
authors.forename: David C
authors.initials: DC
authors.lastname: Naftel
authors.affiliation: Department of Surgery, University of Michigan, Ann Arbor, Michigan.
authors.forename: Francis D
authors.initials: FD
authors.lastname: Pagani
authors.affiliation: Department of Surgery, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, Pennsylvania.
authors.forename: Robert L
authors.initials: RL
authors.lastname: Kormos
authors.affiliation: Department of Medicine, Brigham & Women's Hospital, Boston, Massachusetts.
authors.forename: Lynne W
authors.initials: LW
authors.lastname: Stevenson
authors.affiliation: Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts.
authors.forename: Elizabeth D
authors.initials: ED
authors.lastname: Blume
authors.affiliation: Division of Cardiovascular Diseases, Advanced Technologies and Surgery Branch, National Heart Lung and Blood Institute, Bethesda, Maryland.
authors.forename: Marissa A
authors.initials: MA
authors.lastname: Miller
authors.affiliation: Division of Cardiovascular Diseases, Advanced Technologies and Surgery Branch, National Heart Lung and Blood Institute, Bethesda, Maryland.
authors.forename: J T
authors.initials: JT
authors.lastname: Baldwin
authors.affiliation: Division of Cardiovascular Diseases, Advanced Technologies and Surgery Branch, National Heart Lung and Blood Institute, Bethesda, Maryland.
authors.forename: J
authors.initials: J
authors.lastname: Timothy Baldwin
authors.affiliation: Department of Medicine, Cleveland Clinic Foundation Lerner College of Medicine, Cleveland, Ohio.
authors.forename: James B
authors.initials: JB
authors.lastname: Young
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D016208:Databases, Factual; D005112:Extracorporeal Circulation / Q000009:adverse effects / Q000295:instrumentation / Q000706:statistics & numerical data; D005260:Female; D006333:Heart Failure / Q000628:therapy*; D006353:Heart-Assist Devices / Q000009:adverse effects / Q000706:statistics & numerical data*; D006801:Humans; D007223:Infant; D008297:Male; D011788:Quality of Life; D016019:Survival Analysis; D014481:United States
keywords: INTERMACS; advanced heart failure; destination therapy; mechanical support; ventricular assist device