title: Multifocal osteosarcoma of the skull: multiple primary or metastatic? A case report.
abstract: Osteosarcoma of the skull is a very rare condition. Moreover, it is extremely rare for osteosarcoma to present as multiple lesions confined to the skull. A 58-year-old woman was admitted with two masses in the parietal area of the skull, accompanied by mild headache and tenderness. Imaging revealed two masses with a heterogeneous consistency in the cranial bones. Excision craniectomy was performed and the pathology was consistent with osteoblastic osteosarcoma. Two nodules in the heart were found on routine follow-up imaging while the patient was undergoing chemotherapy. The nodules were biopsied and found to be metastatic osteosarcoma.
authors.affiliation: Department of Pathology, Kyung Hee Medical Center, Kyung Hee University College of Medicine, Seoul, Korea.
authors.forename: Hyuck
authors.initials: H
authors.lastname: Cho
authors.affiliation: Department Neurosurgery, Kyung Hee Medical Center, Kyung Hee University College of Medicine, Seoul, Korea.
authors.forename: Bong-Jin
authors.initials: BJ
authors.lastname: Park
authors.affiliation: Department of Pathology, Kyung Hee Medical Center, Kyung Hee University College of Medicine, Seoul, Korea.
authors.forename: Yong-Koo
authors.initials: YK
authors.lastname: Park
keywords: Multifocal; Osteosarcoma; Skull