title: Recent progress in biointerfaces with controlled bacterial adhesion by using chemical and physical methods.
abstract: Biointerfaces with the controlled adhesion of bacteria are highly important, owing to their wide applications, which range from decreasing the probability of infection to promoting higher efficiency and sensitivity in biocatalysts and biosensors. In this Focus Review, we summarize the recent progress in chemically and physically designed biointerfaces with controlled bacterial adhesion. On one hand, several smart-responsive biointerfaces that can be switched between bacteria-adhesive states and bacteria-resistant states by applying an external stimulus have been rationally designed and developed for adhering and detaching bacteria, whilst, on the other hand, the adhesive behavior of bacteria can be controlled by regulating the topography of the biointerface. In addition, new technologies (i.e., biosensors) and materials (i.e., graphene) provide promising approaches for efficiently controlling the adhesion of bacteria for practical applications.
authors.affiliation: Laboratory of Bio-inspired Smart Interface Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190 (P. R. China), Fax: (+86) 010-82627566.
authors.forename: Jingxin
authors.initials: J
authors.lastname: Meng
authors.forename: Pengchao
authors.initials: P
authors.lastname: Zhang
authors.forename: Shutao
authors.initials: S
authors.lastname: Wang
mesh_terms: D001422:Bacterial Adhesion; D018441:Biofilms; D020099:Coated Materials, Biocompatible; D008855:Microscopy, Electron, Scanning; D013499:Surface Properties
chemical_list: D020099:Coated Materials, Biocompatible
keywords: bacteria; biointerfaces; sensors; surface chemistry; topochemistry