title: Association of synchronous medullary and papillary thyroid carcinomas with primary hyperparathyroidism: first case report and literature review.
abstract: OBJECTIVE
  We report a case of a patient with symptomatic primary hyperparathyroidism who was found, through a thorough radiological investigation, to also have papillary and medullary thyroid carcinomas.
  
  
  METHODS
  A 59-year-old female was diagnosed with primary hyperparathyroidism. A further radiological investigation found suspicious areas within both thyroid lobes that were later diagnosed as foci of papillary and medullary thyroid carcinomas. Appropriate treatment was commenced. Reports of similar occurrences of synchronous thyroid and parathyroid pathologies are discussed.
  
  
  CONCLUSIONS
  To our knowledge, this is the first reported case of two synchronous thyroid cancers occurring in the context of primary hyperparathyroidism. We strongly recommend a thorough radiological investigation of all patients with primary hyperparathyroidism to prevent missing concurrent thyroid cancers.
authors.affiliation: Department of ENT,Conquest Hospital,East Sussex Healthcare NHS Trust,St. Leonards-on-Sea,UK.
authors.forename: L
authors.initials: L
authors.lastname: Cheung
authors.affiliation: Department of Radiology,Eastbourne District General Hospital,UK.
authors.forename: D
authors.initials: D
authors.lastname: Howlett
authors.affiliation: Department of Pathology,Eastbourne District General Hospital,UK.
authors.forename: H
authors.initials: H
authors.lastname: El Teraifi
authors.affiliation: Department of ENT,Conquest Hospital,East Sussex Healthcare NHS Trust,St. Leonards-on-Sea,UK.
authors.forename: P
authors.initials: P
authors.lastname: Kirkland
mesh_terms: D002277:Carcinoma / Q000150:complications* / Q000473:pathology; D018278:Carcinoma, Neuroendocrine; D002291:Carcinoma, Papillary; D005260:Female; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000209:etiology* / Q000473:pathology; D033162:Incidental Findings; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000150:complications* / Q000473:pathology; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000150:complications* / Q000473:pathology