title: MM-MTA for direct pulp capping: a histologic comparison with ProRoot MTA in rat molars.
abstract: OBJECTIVE
  To compare the histomorphological response of rat dental pulps capped with MM-MTA and ProRoot MTA at 1, 2 and 4 weeks postoperatively.
  
  
  METHODS
  Direct pulp capping with MM-MTA and ProRoot MTA, overlaid with light-cured composite resin, was performed on right and left maxillary first molars of 20 Wistar rats. Animals were killed at 1, 2 and 4 weeks postoperatively. Biopsy samples were stained and viewed by light microscopy to determine dentin bridge formation. Data were statistically evaluated with the Kruskal-Wallis test (p < 0.05).
  
  
  RESULTS
  Absence of dentin bridge formation at 1 week, partial dentin bridge formation at 2 weeks and complete dentin bridge formation at 4 weeks are observed with MM-MTA and ProRoot MTA. The results showed no statistically significant difference between both materials at 4 weeks.
  
  
  CONCLUSIONS
  Both materials produced similar responses in the pulp when used for pulp capping in intact, caries-free molars of rats.
authors.affiliation: Assistant Professor, Department of Endodontics, Saint Joseph University, Lebanon, e-mail: isamklil@cyberia.net.lb.
authors.forename: Issam Tanios
authors.initials: IT
authors.lastname: Khalil
authors.affiliation: Private Practice, Department of Endodontics, Lebanon.
authors.forename: Tony
authors.initials: T
authors.lastname: Sarkis
authors.affiliation: Chairman, Department of Endodontics, Saint Joseph University Lebanon.
authors.forename: Alfred
authors.initials: A
authors.lastname: Naaman
mesh_terms: D017607:Aluminum Compounds / Q000737:chemistry / Q000627:therapeutic use*; D000818:Animals; D002119:Calcium Carbonate / Q000737:chemistry / Q000627:therapeutic use; D017610:Calcium Compounds / Q000737:chemistry / Q000627:therapeutic use*; D002133:Calcium Sulfate / Q000737:chemistry / Q000627:therapeutic use; D003188:Composite Resins / Q000737:chemistry; D003789:Dental Pulp Exposure / Q000628:therapy; D003793:Dental Restoration, Permanent / Q000379:methods; D003809:Dentin, Secondary / Q000187:drug effects / Q000473:pathology; D017220:Dentin-Bonding Agents / Q000737:chemistry; D004338:Drug Combinations; D008963:Molar / Q000187:drug effects* / Q000473:pathology; D010087:Oxides / Q000737:chemistry / Q000627:therapeutic use*; D057872:Pulp Capping and Pulpectomy Agents / Q000737:chemistry / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar; D017640:Silicates / Q000737:chemistry / Q000627:therapeutic use*
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D003188:Composite Resins; D017220:Dentin-Bonding Agents; D004338:Drug Combinations; D010087:Oxides; D057872:Pulp Capping and Pulpectomy Agents; D017640:Silicates; C086631:mineral trioxide aggregate; D002119:Calcium Carbonate; D002133:Calcium Sulfate