title: Homocysteine serum levels in diabetic patients with non proliferative, proliferative and without retinopathy.
abstract: Homocysteine has been associated with extracellular matrix changes. The diabetic retinopathy is a neurovascular complication of diabetes mellitus and it is the leading cause of vision loss among working adults worldwide. In this study, we evaluate the role of homocysteine in diabetic retinopathy analyzing the plasma levels of homocysteine in 63 diabetic type 2 patients with nonproliferative retinopathy (NPDR), 62 patients with proliferative diabetic retinopathy (PDR), 50 healthy subjects used as control group, and 75 randomly selected patients.
authors.affiliation: International Ph.D. programme in Neuropharmacology, University of Catania, 95123 Catania, Italy.
authors.forename: Giulia
authors.identifier: 0000-0003-3655-4307
authors.initials: G
authors.lastname: Malaguarnera
authors.affiliation: Department of Ophthalmology, University of Catania, 95123 Catania, Italy.
authors.forename: Caterina
authors.initials: C
authors.lastname: Gagliano
authors.affiliation: Research Center "The Great Senescence", University of Catania, 95125 Catania, Italy.
authors.forename: Maria
authors.initials: M
authors.lastname: Giordano
authors.affiliation: International Ph.D. programme in Neuropharmacology, University of Catania, 95123 Catania, Italy ; Section of Pharmacology and Biochemistry, Department of Clinical and Molecular Biomedicine, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy.
authors.forename: Salvatore
authors.identifier: 0000-0001-5307-6103
authors.initials: S
authors.lastname: Salomone
authors.affiliation: Research Center "The Great Senescence", University of Catania, 95125 Catania, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Vacante
authors.affiliation: International Ph.D. programme in Neuropharmacology, University of Catania, 95123 Catania, Italy ; Section of Pharmacology and Biochemistry, Department of Clinical and Molecular Biomedicine, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy.
authors.forename: Claudio
authors.identifier: 0000-0002-4879-4140
authors.initials: C
authors.lastname: Bucolo
authors.affiliation: International Ph.D. programme in Neuropharmacology, University of Catania, 95123 Catania, Italy ; IRCCS, Oasi Maria S.S.-Institute for Research on Mental Retardation and Brain Aging, 94018 Troina, Italy ; Department of Educational Sciences, University of Catania, Via Teatro Greco 84, 95124 Catania, Italy.
authors.forename: Filippo
authors.initials: F
authors.lastname: Caraci
authors.affiliation: Department of Ophthalmology, University of Catania, 95123 Catania, Italy.
authors.forename: Michele
authors.identifier: 0000-0003-1368-6729
authors.initials: M
authors.lastname: Reibaldi
authors.affiliation: International Ph.D. programme in Neuropharmacology, University of Catania, 95123 Catania, Italy ; Section of Pharmacology and Biochemistry, Department of Clinical and Molecular Biomedicine, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy.
authors.forename: Filippo
authors.initials: F
authors.lastname: Drago
authors.affiliation: Department of Ophthalmology, University of Catania, 95123 Catania, Italy.
authors.forename: Teresio
authors.initials: T
authors.lastname: Avitabile
authors.affiliation: Research Center "The Great Senescence", University of Catania, 95125 Catania, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Motta
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001766:Blindness / Q000097:blood* / Q000209:etiology; D003930:Diabetic Retinopathy / Q000097:blood*; D005260:Female; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D006710:Homocysteine