title: Inactivation of avian influenza virus, newcastle disease virus and goose parvovirus using solution of nano-sized scallop shell powder.
abstract: Scallop shell powder produced by calcination process - the average diameter of the powder particles being 20 µm (SSP) - was further ground into nano-sized particles, with average diameter of 500 nm, here designated CaO-Nano. Solution of CaO-Nano could inactivate avian influenza virus within 5 sec, whereas the solution of SSP could not even after 1 hr incubation. CaO-Nano solution could also inactivate Newcastle disease virus and goose parvovirus within 5 sec and 30 sec, respectively. The virus-inactivating capacity (neutralizing index: NI>3) of the solution was not reduced by the presence of 20% fetal bovine serum. CaO-Nano solution seems to be a good candidate of materials for enhancement of biosecurity in farms.
authors.affiliation: Laboratory of Animal Health, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo 183-8509, Japan.
authors.forename: Chanathip
authors.initials: C
authors.lastname: Thammakarn
authors.forename: Keisuke
authors.initials: K
authors.lastname: Satoh
authors.forename: Atsushi
authors.initials: A
authors.lastname: Suguro
authors.forename: Hakimullah
authors.initials: H
authors.lastname: Hakim
authors.forename: Sakchai
authors.initials: S
authors.lastname: Ruenphet
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Takehara
mesh_terms: D060105:Animal Shells; D000818:Animals; D002118:Calcium / Q000494:pharmacology*; D009980:Influenza A virus / Q000254:growth & development*; D053758:Nanoparticles / Q000008:administration & dosage*; D009500:Neutralization Tests / Q000662:veterinary; D009522:Newcastle disease virus / Q000254:growth & development*; D017992:Parvovirus / Q000254:growth & development*; D049897:Pectinidae; D011201:Poultry Diseases / Q000517:prevention & control / Q000821:virology*; D038301:Virus Inactivation
chemical_list: D002118:Calcium