title: Vortex-assisted magnetic dispersive solid-phase microextraction for rapid screening and recognition of dicofol residues in tea products.
abstract: A simple and rapid vortex-assisted magnetic dispersive solid-phase microextraction (VAMDSME) method coupled with gas chromatography-electronic capture detection was developed for rapid screening and selective recognition of dicofol in tea products. The magnetic molecularly imprinted microspheres (mag-MIMs) synthesised by aqueous suspension polymerisation using dichlorodiphenyltrichloroethane (DDT) as a dummy template showed high selectivity and affinity to dicofol in aqueous solution and were successfully applied as special adsorbents of VAMDSME for rapid isolation of dicofol from complex tea matrix. Good linearity was obtained in a range of 0.2-160 ng g(-1) and the limit of detection based on a signal to noise ratio of 3 was 0.05 ng g(-1). The recoveries at three spiked levels ranged from 83.6% to 94.5% with the related standard deviations (RSD) ⩽ 5.0%. The VAMDSME-GC protocol, which took advantages of the selective adsorption of molecularly imprinted microspheres and rapid magnetic phase separation, as well as the short equilibrium time by vortex-assisted, could avoid the time-consuming procedures related to other traditional extraction methods.
authors.affiliation: Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education & College of Pharmaceutical Sciences, Hebei University, Baoding 071002, China; Beijing Children's Hospital Affiliated to Capital University of Medical Sciences, Beijing 100045, China.
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Cheng
authors.affiliation: Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education & College of Pharmaceutical Sciences, Hebei University, Baoding 071002, China. Electronic address: yanhy@hbu.edu.cn.
authors.forename: Hongyuan
authors.initials: H
authors.lastname: Yan
authors.affiliation: Beijing Children's Hospital Affiliated to Capital University of Medical Sciences, Beijing 100045, China.
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Wang
authors.affiliation: Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education & College of Pharmaceutical Sciences, Hebei University, Baoding 071002, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Sun
authors.affiliation: Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education & College of Pharmaceutical Sciences, Hebei University, Baoding 071002, China.
authors.forename: Xiaoqiang
authors.initials: X
authors.lastname: Qiao
mesh_terms: D002849:Chromatography, Gas / Q000379:methods; D002853:Chromatography, Liquid / Q000379:methods*; D004010:Dicofol / Q000737:chemistry*; D060328:Magnetic Phenomena; D052617:Solid Phase Microextraction / Q000379:methods*; D013662:Tea / Q000009:adverse effects* / Q000737:chemistry
chemical_list: D013662:Tea; D004010:Dicofol
keywords: Column liquid chromatography; Dicofol; Dummy molecularly imprinted microspheres; Magnetic dispersive solid-phase microextraction; Tea products