title: Peri-stent contrast staining, major evaginations and severe malapposition after biolimus-eluting stent implantation: a case report based on coronary optical frequency domain imaging.
abstract: Peri-stent contrast staining and late acquired malapposition represent pathological vessel wall healing patterns following percutaneous coronary intervention with stent implantation. Earlier studies have described these abnormal vessel wall responses commonly present after implantation of first-generation drug-eluting stents. These coronary vascular changes can cause flow disturbance and thereby dispose for later thrombotic events. This case report, based on coronary optical frequency domain imaging, describes peri-stent contrast staining, major evaginations and severe malapposition occurring 18months after third-generation biolimus-eluting stent implantation.
authors.affiliation: Department of Cardiology, Odense University Hospital, Odense, Denmark. Electronic address: dr_lissie@hotmail.com.
authors.forename: Lisbeth
authors.initials: L
authors.lastname: Antonsen
authors.affiliation: Department of Cardiology, Odense University Hospital, Odense, Denmark.
authors.forename: Per
authors.initials: P
authors.lastname: Thayssen
authors.affiliation: Department of Cardiology, Odense University Hospital, Odense, Denmark.
authors.forename: Lisette Okkels
authors.initials: LO
authors.lastname: Jensen
mesh_terms: D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000175:diagnosis / Q000000981:diagnostic imaging*; D003331:Coronary Vessels / Q000473:pathology* / Q000601:surgery; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000379:methods; D020123:Sirolimus / Q000031:analogs & derivatives / Q000627:therapeutic use; D013194:Staining and Labeling; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: C518022:umirolimus; D020123:Sirolimus
keywords: Biolimus-eluting stent; Major evaginations; Malapposition; Optical frequency domain imaging; Peri-stent contrast staining