title: Assessment and comparison of anemia of chronic disease in healthy subjects and chronic periodontitis patients: A clinical and hematological study.
abstract: BACKGROUND
  Bacteremia is associated with periodontal diseases whose extent is related to the severity of inflammation in periodontal tissues. The purpose of this study was to assess and compare the various blood parameters in healthy subjects and severe chronic periodontitis patients.
  
  
  METHODS
  100 patients with severe chronic periodontitis (test group) and 100 periodontally healthy subjects (control group) in the age group 35-60 years participated in the study. Blood parameters were recorded with blood samples drawn from the antecubital fossa by venous puncture.
  
  
  RESULTS
  Periodontitis group showed lower erythrocyte count and mean corpuscular hemoglobin concentration (MCHC), and increased total leukocyte count (TLC) and neutrophil, lymphocyte, and eosinophil count, compared to the healthy control group.
  
  
  CONCLUSIONS
  To conclude, periodontitis may tend toward anemia and there is marked leukocytosis due to increased number of circulating neutrophils and lymphocytes.
authors.affiliation: Department of Periodontics, VSPM Dental College and Research Centre, Nagpur, Maharashtra, India.
authors.forename: Rajashri A
authors.initials: RA
authors.lastname: Kolte
authors.affiliation: Department of Periodontics, VSPM Dental College and Research Centre, Nagpur, Maharashtra, India.
authors.forename: Abhay P
authors.initials: AP
authors.lastname: Kolte
authors.affiliation: Department of Periodontics, VSPM Dental College and Research Centre, Nagpur, Maharashtra, India.
authors.forename: Neha M
authors.initials: NM
authors.lastname: Deshpande
keywords: Anemia of chronic disease; bacteremia; chronic periodontitis; systemic inflammation