title: Sleep duration and abnormal serum lipids: the China Health and Nutrition Survey.
abstract: OBJECTIVE
  To examine the associations between sleep duration and total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), apolipoprotein B (ApoB), apolipoprotein A1 (ApoA1), and lipoprotein (a) [Lp(a)].
  
  
  METHODS
  The present study analyzed 8574 adults from the China Health and Nutrition Survey (2009). Sleep duration was classified into < or = 6, 7, 8, 9, and > or = 10 h. Age, education, occupation, current smoking, current drinking, physical activity, body mass index, hypertension, and diabetes were adjusted as confounders in gender-stratified multiple logistic regression models.
  
  
  RESULTS
  Compared with women reporting 8h sleep duration, the odds ratios (ORs) and 95% confidence intervals (CIs) of high TC for those with < or = 6, 7, 9, and > or = 10 h were 1.65 (1.32-2.06), 1.19 (1.00-1.43), 1.11 (0.89-1.39), and 1.27 (1.02-1.60) after adjusting for confounders. Likewise, the ORs (95% CIs) of high LDL-C were 1.71 (1.28-2.29), 1.36 (1.05-1.76), 1.04 (0.74-1.46), and 1.09 (0.78-1.53), whereas those of high ApoB were 1.80 (1.34-2.42), 1.15 (0.88-1.52), 0.95 (0.66-1.35), and 1.00 (0.70-1.43) for women with < or = 6, 7, 9, and > or = 10 h sleep duration, respectively. These associations were not statistically significant in men.
  
  
  CONCLUSIONS
  Both shorter and longer sleep durations were associated with higher risks of abnormal serum lipid profiles in women but not in men.
authors.affiliation: Institute of Clinical Epidemiology, School of Public Health, Fudan University, Shanghai, PR China.
authors.forename: Yiqiang
authors.initials: Y
authors.lastname: Zhan
authors.affiliation: Institute of Clinical Epidemiology, School of Public Health, Fudan University, Shanghai, PR China.
authors.forename: Ruoqing
authors.initials: R
authors.lastname: Chen
authors.affiliation: Institute of Clinical Epidemiology, School of Public Health, Fudan University, Shanghai, PR China. Electronic address: jmy@fudan.edu.cn.
authors.forename: Jinming
authors.initials: J
authors.lastname: Yu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016632:Apolipoprotein A-I / Q000097:blood; D001055:Apolipoproteins B / Q000097:blood; D002681:China / Q000453:epidemiology; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D006970:Disorders of Excessive Somnolence / Q000097:blood / Q000503:physiopathology; D005260:Female; D006306:Health Surveys; D006801:Humans; D008055:Lipids / Q000097:blood*; D017270:Lipoprotein(a) / Q000097:blood; D008297:Male; D008875:Middle Aged; D012723:Sex; D012890:Sleep / Q000502:physiology*; D012892:Sleep Deprivation / Q000097:blood / Q000503:physiopathology; D014280:Triglycerides / Q000097:blood; D055815:Young Adult
chemical_list: C505693:APOA1 protein, human; D016632:Apolipoprotein A-I; D001055:Apolipoproteins B; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D017270:Lipoprotein(a); D014280:Triglycerides; D002784:Cholesterol
keywords: China Health and Nutrition Survey; Cholesterol; Dyslipidemia; Lipoprotein (a); Sleep duration; Triglyceride