title: Controversy over radioiodine ablation in thyroid cancer: who benefits?
abstract: Recent studies have proposed that overdiagnosis is probably the principal cause of the increased incidence of thyroid cancer. The controversy around radioiodine ablation is complicated by the ever increasing numbers of small, low-risk thyroid cancers being diagnosed. This article examines the history and evolving epidemiology of the disease and treatment.
authors.affiliation: Department of Diagnostic Imaging, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, 593 Eddy Street, Providence, RI 02903, USA. Electronic address: dyoo@lifespan.org.
authors.forename: Don C
authors.initials: DC
authors.lastname: Yoo
authors.affiliation: Department of Diagnostic Imaging, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, 593 Eddy Street, Providence, RI 02903, USA.
authors.forename: Richard B
authors.initials: RB
authors.lastname: Noto
authors.affiliation: Department of General Surgery, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, 593 Eddy Street, Providence, RI 02903, USA.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Mazzaglia
mesh_terms: D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D013964:Thyroid Neoplasms / Q000532:radiotherapy*; D016896:Treatment Outcome
chemical_list: D007457:Iodine Radioisotopes
keywords: Overdiagnosis; RIA; Radioiodine ablation; Risk stratification; Thyroid cancer