title: 50 Years of progress in the systemic therapy of non-small cell lung cancer.
abstract: Non-small cell lung cancer constitutes 85% to 90% of lung cancer and is the most common cause of cancer death. Over the past 50 years, substantial progress has been made in all aspects of lung cancer including screening, diagnostic evaluation, surgery, radiation therapy, and chemotherapy. This review focuses on the advances in systemic therapy during this half century.
authors.affiliation: From the Stanford Cancer Institute, Stanford University, Stanford, CA; University of California, Davis Cancer Center, Sacramento, CA; University of New Mexico Cancer Center, Albuquerque, NM.
authors.forename: Heather
authors.initials: H
authors.lastname: Wakelee
authors.affiliation: From the Stanford Cancer Institute, Stanford University, Stanford, CA; University of California, Davis Cancer Center, Sacramento, CA; University of New Mexico Cancer Center, Albuquerque, NM.
authors.forename: Karen
authors.initials: K
authors.lastname: Kelly
authors.affiliation: From the Stanford Cancer Institute, Stanford University, Stanford, CA; University of California, Davis Cancer Center, Sacramento, CA; University of New Mexico Cancer Center, Albuquerque, NM.
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Edelman
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000266:history / Q000627:therapeutic use*; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy* / Q000266:history / Q000276:immunology / Q000401:mortality / Q000473:pathology; D017024:Chemotherapy, Adjuvant; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D007167:Immunotherapy; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000266:history / Q000276:immunology / Q000401:mortality / Q000473:pathology; D008495:Medical Oncology / Q000266:history / Q000639:trends*; D058990:Molecular Targeted Therapy; D011013:Pneumonectomy; D018714:Radiotherapy, Adjuvant; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents