title: Copper-catalyzed aerobic oxidative N-S bond functionalization for C-S bond formation: regio- and stereoselective synthesis of sulfones and thioethers.
abstract: A regio- and stereoselective synthesis of sulfones and thioethers by means of Cu(I)-catalyzed aerobic oxidative N-S bond cleavage of sulfonyl hydrazides, followed by cross-coupling reactions with alkenes and aromatic compounds to form the C sp 2-S bond, is described herein. N2 and H2O are the byproducts of this transformation, thus offering an environmentally benign process with a wide range of potential applications in organic synthesis and medicinal chemistry.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology.
authors.forename: Xianwei
authors.initials: X
authors.lastname: Li
authors.forename: Yanli
authors.initials: Y
authors.lastname: Xu
authors.forename: Wanqing
authors.initials: W
authors.lastname: Wu
authors.forename: Chang
authors.initials: C
authors.lastname: Jiang
authors.forename: Chaorong
authors.initials: C
authors.lastname: Qi
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang
keywords: CH functionalization; copper; oxygen; sulfones; thioethers