title: Efficient synthesis of fluorescent-PET probes based on [¹⁸F]BODIPY dye.
abstract: We report the direct conversion of fluorescent probes to PET/fluorescent probes after efficient [(19)F]/[(18)F] exchange at the BODIPY motif. The radiolabeling of a NIR BODIPY dye was also established, which was conjugated with the RGD peptide for PET/fluorescence imaging of integrin expression in vivo.
authors.affiliation: Molecular Imaging Center, Radiology Department, University of Southern California, 2250 Alcazar St CSC103, Los Angeles, CA, USA. ziboli@usc.edu.
authors.forename: Shuanglong
authors.initials: S
authors.lastname: Liu
authors.forename: Dan
authors.initials: D
authors.lastname: Li
authors.forename: Zhe
authors.initials: Z
authors.lastname: Zhang
authors.forename: G K
authors.initials: GK
authors.lastname: Surya Prakash
authors.forename: Peter S
authors.initials: PS
authors.lastname: Conti
authors.forename: Zibo
authors.initials: Z
authors.lastname: Li
mesh_terms: D000818:Animals; D001896:Boron Compounds / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis*; D051379:Mice; D009842:Oligopeptides / Q000737:chemistry; D049268:Positron-Emission Tomography
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D005456:Fluorescent Dyes; D009842:Oligopeptides; C047981:arginyl-glycyl-aspartic acid