title: Voltammetric behavior of dopamine at a glassy carbon electrode modified with NiFe(2)O(4) magnetic nanoparticles decorated with multiwall carbon nanotubes.
abstract: Voltammetric behavior of dopamine was studied on a glassy carbon electrode (GCE) modified-NiFe(2)O(4) magnetic nanoparticles decorated with multiwall carbon nanotubes. Impedance spectroscopy and cyclic voltammetry were used to characterize the behavior of dopamine at the surface of modified-GCE. The modified electrode showed a synergic effect toward the oxidation of dopamine. The oxidation peak current is increased linearly with the dopamine concentration (at pH7.0) in wide dynamic ranges of 0.05-6.0 and 6.0-100μmolL(-1) with a detection limit of 0.02μmolL(-1), using differential pulse voltammetry. The selectivity of the method was studied and the results showed that the modified electrode is free from interference of organic compounds especially ascorbic acid, uric acid, cysteine and urea. Its applicability in the determination of dopamine in pharmaceutical, urine samples and human blood serum was also evaluated. The proposed electrochemical sensor has appropriate properties such as high selectivity, low detection limit and wide linear dynamic range when compared with that of the previous reported papers for dopamine detection.
authors.affiliation: Department of Chemistry, Isfahan University of Technology, Isfahan 84156-83111, Iran. Electronic address: Ensafi@cc.iut.ac.ir.
authors.forename: Ali A
authors.initials: AA
authors.lastname: Ensafi
authors.affiliation: Department of Chemistry, Isfahan University of Technology, Isfahan 84156-83111, Iran.
authors.forename: B
authors.initials: B
authors.lastname: Arashpour
authors.affiliation: Department of Chemistry, Isfahan University of Technology, Isfahan 84156-83111, Iran.
authors.forename: B
authors.initials: B
authors.lastname: Rezaei
authors.affiliation: Nanotechnology and Advanced Materials Institute, Isfahan University of Technology, Isfahan 84156-83111, Iran.
authors.forename: Ali R
authors.initials: AR
authors.lastname: Allafchian
mesh_terms: D001205:Ascorbic Acid / Q000737:chemistry; D015415:Biomarkers / Q000097:blood / Q000652:urine; D002244:Carbon / Q000737:chemistry*; D003545:Cysteine / Q000737:chemistry; D058266:Dielectric Spectroscopy; D004298:Dopamine / Q000032:analysis*; D004566:Electrodes; D006801:Humans; D006863:Hydrogen-Ion Concentration; D057230:Limit of Detection; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D037742:Nanotubes, Carbon / Q000737:chemistry*; D014527:Uric Acid / Q000737:chemistry
chemical_list: D015415:Biomarkers; D058185:Magnetite Nanoparticles; D037742:Nanotubes, Carbon; D014527:Uric Acid; D002244:Carbon; D003545:Cysteine; D001205:Ascorbic Acid; D004298:Dopamine
keywords: Dopamine determination; NiFe(2)O(4) nanoparticles decorated with multiwall carbon nanotubes; Synergic effect; Voltammetry