title: A new stationary phase for high performance liquid chromatography: Calix[4]arene derivatized chitosan bonded silica gel.
abstract: In the present paper, a new calix[4]arene derivatized chitosan bonded stationary phase (CCS4) for high performance liquid chromatography (HPLC) was synthesized and characterized. Its chromatographic performance and retention mechanism were evaluated in reversed-phase mode compared with ODS using different solute probes including mono-substituted benzenes, phenols and nucleosides. The results showed that CCS4 stationary phase could provide various interactions with solutes, such as hydrophobic, hydrophilic, π-π, and inclusion interactions. It could perform the mixed-mode separation including RP and HILIC.
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.
authors.forename: Jing
authors.initials: J
authors.lastname: Lu
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.
authors.forename: Wenfen
authors.initials: W
authors.lastname: Zhang
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.
authors.forename: Yanhao
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China; School of Chemistry and Chemical Engineering, Henan University of Technology, Zhengzhou 450001, PR China.
authors.forename: Wenjie
authors.initials: W
authors.lastname: Zhao
authors.affiliation: Henan University of Traditional Chinese Medicine, Zhengzhou 450008, PR China.
authors.forename: Kai
authors.initials: K
authors.lastname: Hu
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.
authors.forename: Ajuan
authors.initials: A
authors.lastname: Yu
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China. Electronic address: liupu@zzu.edu.cn.
authors.forename: Pu
authors.initials: P
authors.lastname: Liu
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.
authors.forename: Yangjie
authors.initials: Y
authors.lastname: Wu
authors.affiliation: Key Laboratory of Chemical Biology and Organic Chemistry of Henan, Zhengzhou University, Zhengzhou 450052, PR China. Electronic address: zhangshusheng@371.net.
authors.forename: Shusheng
authors.initials: S
authors.lastname: Zhang
mesh_terms: D047250:Calixarenes / Q000737:chemistry*; D048271:Chitosan / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation*; D057927:Hydrophobic and Hydrophilic Interactions; D009930:Organic Chemicals / Q000737:chemistry; D010636:Phenols / Q000737:chemistry*; D058428:Silica Gel / Q000737:chemistry*
chemical_list: D009930:Organic Chemicals; D010636:Phenols; C121325:calix(4)arene; D047250:Calixarenes; D058428:Silica Gel; D048271:Chitosan
keywords: Calix[4]arene; Chitosan; HILIC; Mixed-mode separation; RPLC; Stationary phase