title: A case of vascular hemichorea responding to topiramate.
abstract: Although vascular chorea often comes into remission spontaneously, a few patients may remain with persistent movement disorder. Most movements respond well to neuroleptics as well as other antidopaminergic drugs, but some patients show poor responses to those neuroleptics. Topiramate is a widely used of broad-spectrum anticonvulsant possessing a complex mechanism of action. It has been proven to enhance gamma-aminobutyrate acid activity and to be effective in the control of other movement disorders. We describe a 63-year-old woman with intractable vascular hemichorea which was controlled with anti-convulsant, topiramate.
authors.affiliation: Department of Neurology, Hallym University College of Medicine, Seoul, Korea.
authors.forename: Jee-Ae
authors.initials: JA
authors.lastname: Kim
authors.affiliation: Department of Neurology, Hallym University College of Medicine, Seoul, Korea.
authors.forename: San
authors.initials: S
authors.lastname: Jung
authors.affiliation: Department of Neurology, Hallym University College of Medicine, Seoul, Korea.
authors.forename: Min-Ju
authors.initials: MJ
authors.lastname: Kim
authors.affiliation: Department of Neurology, Hallym University College of Medicine, Seoul, Korea.
authors.forename: Seok-Beom
authors.initials: SB
authors.lastname: Kwon
authors.affiliation: Department of Neurology, Hallym University College of Medicine, Seoul, Korea.
authors.forename: Sung-Hee
authors.initials: SH
authors.lastname: Hwang
authors.affiliation: Department of Neurology, Hallym University College of Medicine, Seoul, Korea.
authors.forename: Ki-Han
authors.initials: KH
authors.lastname: Kwon
keywords: Anticonvulsant; Hemichorea; Topiramate