title: Mining seasonal marine microbial pattern with greedy heuristic clustering and symmetrical nonnegative matrix factorization.
abstract: With the development of high-throughput and low-cost sequencing technology, a large number of marine microbial sequences were generated. The association patterns between marine microbial species and environment factors are hidden in these large amount sequences. Mining these association patterns is beneficial to exploit the marine resources. However, very few marine microbial association patterns are well investigated in this field. The present study reports the development of a novel method called HC-sNMF to detect the marine microbial association patterns. The results show that the four seasonal marine microbial association networks have characters of complex networks, the same environmental factor influences different species in the four seasons, and the correlative relationships are stronger between OTUs (taxa) than with environmental factors in the four seasons detecting community.
authors.affiliation: College of Automation, Northwestern Polytechnical University, Xi'an 710072, China ; Key Laboratory of Information Fusion Technology, Ministry of Education, Xi'an 710072, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Liu
authors.affiliation: College of Automation, Northwestern Polytechnical University, Xi'an 710072, China ; Key Laboratory of Information Fusion Technology, Ministry of Education, Xi'an 710072, China.
authors.forename: Shao-Wu
authors.initials: SW
authors.lastname: Zhang
authors.affiliation: College of Automation, Northwestern Polytechnical University, Xi'an 710072, China ; Key Laboratory of Information Fusion Technology, Ministry of Education, Xi'an 710072, China.
authors.forename: Ze-Gang
authors.initials: ZG
authors.lastname: Wei
authors.affiliation: College of Automation, Northwestern Polytechnical University, Xi'an 710072, China ; Key Laboratory of Information Fusion Technology, Ministry of Education, Xi'an 710072, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Chen
authors.affiliation: College of Automation, Northwestern Polytechnical University, Xi'an 710072, China ; Key Laboratory of Information Fusion Technology, Ministry of Education, Xi'an 710072, China.
authors.forename: Chen
authors.initials: C
authors.lastname: Zhou
mesh_terms: D059001:Aquatic Organisms / Q000145:classification / Q000235:genetics*; D030561:Databases, Nucleic Acid; D017753:Ecosystem; D059014:High-Throughput Nucleotide Sequencing / Q000379:methods*; D014871:Water Microbiology