title: Cardiac (123)I-metaiodobenzylguanidine Scintigraphy in a Patient with Familial Parkinsonism with Parkin Gene Mutation.
abstract: A decreased cardiac (123)I-metaiodobenzylguanidine ((123)I-MIBG) uptake has been used as a powerful tool to identify Lewy body disease, such as idiopathic parkinson's disease (IPD). We performed cardiac (123)I-MIBG scintigraphy in patient with autosomal recessive juvenile parkinsonism (ARJP) with parkin gene mutation (PARK2). The findings showed normal cardiac (123)I-MIBG uptake. Therefore, although the clinical features of ARJP are sometimes quite similar to those of late-onset IPD, cardiac (123)I-MIBG scintigraphy may be used as a valuable tool to identify patients with IPD and to distinguish them from patients with other parkinsonian syndromes.
authors.affiliation: Department of Neurology, The Catholic University of Korea, College of Medicine, Seoul St. Mary's Hospital, Seoul, Korea.
authors.forename: Young-Do
authors.initials: YD
authors.lastname: Kim
authors.affiliation: Department of Neurology, The Catholic University of Korea, College of Medicine, Seoul St. Mary's Hospital, Seoul, Korea.
authors.forename: In-Uk
authors.initials: IU
authors.lastname: Song
authors.affiliation: Department of Neurology, The Catholic University of Korea, College of Medicine, Seoul St. Mary's Hospital, Seoul, Korea.
authors.forename: Joong-Seok
authors.initials: JS
authors.lastname: Kim
authors.affiliation: Department of Neurology, The Catholic University of Korea, College of Medicine, Seoul St. Mary's Hospital, Seoul, Korea.
authors.forename: Sung-Woo
authors.initials: SW
authors.lastname: Chung
authors.affiliation: Department of Neurology, The Catholic University of Korea, College of Medicine, Seoul St. Mary's Hospital, Seoul, Korea.
authors.forename: Kwang-Soo
authors.initials: KS
authors.lastname: Lee
keywords: 123I-metaiodobenzylguanidine; Autosomal recessive juvenile parkinsonism; Parkin gene