title: Coronary artery abnormalities in Kawasaki disease.
abstract: BACKGROUND
  Kawasaki disease is the number one cause of acquired heart disease among children in developed countries.
  
  
  OBJECTIVE
  The aim of the study was a retrospective analysis of the factors that may influence the persistence of coronary artery abnormalities in patients with Kawasaki disease.
  
  
  METHODS
  Analyzing the medical records of patients hospitalized in the University Children's Hospital of Krakow in the years 2005-2011 we collected the data of 28 patients diagnosed with Kawasaki disease. The group was divided into two subgroups, depending on the duration of the persistence of changes in the coronary arteries - A (n = 17) for up to 6 months, B (n = 11) - for more than 6 months. Both groups were analyzed for the presence of factors that may influence the course of the disease.
  
  
  RESULTS
  There were more boys in group A (11 boys (65%), 6 girls (35%)), whereas in group B the distribution was more uniform (6 boys (55%), 5 girls (45%)). The age of onset in group A was 37.9 months (SD 30.8), in group B 39.5 months (SD 16.7). 17.6% of patients in group A and 36.4% in group B were treated with glucocorticoids.
  
  
  CONCLUSIONS
  In the group of patients in which coronary artery abnormalities disappeared more quickly, male and slightly older children dominated. The only difference observed between the 2 groups related to the frequency of the use of glucocorticoids, they were used more often in children, in whom coronary artery abnormalities persisted longer.
authors.affiliation: Department of Pediatrics, Jagiellonian University Medical College, Krakow, Poland. zasada.magdallena@gmail.com.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Zasada
authors.affiliation: Department of Pediatrics, Jagiellonian University Medical College, Krakow, Poland.
authors.forename: Karolina
authors.initials: K
authors.lastname: Poplawska
authors.affiliation: Department of Pediatrics, Jagiellonian University Medical College, Krakow, Poland.
authors.forename: Paulina
authors.initials: P
authors.lastname: Mazurek
authors.affiliation: Department of Pediatrics, Jagiellonian University Medical College, Krakow, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Rzucidlo-Hymczak
authors.affiliation: Department of Pediatric Cardiology, Jagiellonian University Medical College, Krakow, Poland.
authors.forename: Jacek
authors.initials: J
authors.lastname: Kuzma
authors.affiliation: Department of Pediatric Cardiology, Jagiellonian University Medical College, Krakow, Poland.
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Kordon
authors.affiliation: Department of Pediatrics, Jagiellonian University Medical College, Krakow, Poland.
authors.forename: Bozena
authors.initials: B
authors.lastname: Pilch
authors.affiliation: Department of Pediatric Cardiology, Jagiellonian University Medical College, Krakow, Poland.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Rudzinski
authors.affiliation: Department of Pediatrics, Jagiellonian University Medical College, Krakow, Poland.
authors.forename: Jacek J
authors.initials: JJ
authors.lastname: Pietrzyk
mesh_terms: D002648:Child; D002675:Child, Preschool; D003330:Coronary Vessel Anomalies / Q000473:pathology*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000188:drug therapy* / Q000473:pathology*; D011044:Poland; D012189:Retrospective Studies
chemical_list: D005938:Glucocorticoids