title: Quality of life in patients with cystic fibrosis depending on the severity of the disease and method of its treatment.
abstract: BACKGROUND
  Quality of life is a measure not only of disease severity and its functional impact (physical, psychological, and social functioning) but also the efficacy of novel therapies. The aim of this study was to analyze the quality of life in cystic fibrosis patients depending on the severity of the disease and methods of its treatment.
  
  
  METHODS
  The study included groups of cystic fibrosis patients: 1) after lung transplantation, 2) requiring chronic oxygen therapy, and 3) in stable clinical status. Forty-five men and women older than 18 years were enrolled. The participants were examined with the Polish version of the Cystic Fibrosis Quality of Life Questionnaire (CFQoL) adapted by Dębska & Mazurek.
  
  
  RESULTS
  Patients from analyzed groups differed significantly in terms of their quality of life in most of the subscales included in CFQoL, but not in Future Concerns and Interpersonal Relationships.
  
  
  CONCLUSIONS
  Although lung transplantation markedly improves the quality of life of patients with cystic fibrosis, they still experience problems with social functioning and future concerns.
authors.affiliation: Andrzej Frycz Modrzewski Krakow University Faculty of Health and Medical Studies.
authors.forename: Grażyna
authors.initials: G
authors.lastname: Dębska
authors.affiliation: Jagiellonian University, Collegium Medicum Faculty of Health Sciences, Nursing and Midwifery Institute, Department of Clinical Nursing.
authors.forename: Grażyna
authors.initials: G
authors.lastname: Cepuch
authors.affiliation: Department of Pneumology and Cystic Fibrosis, Institute of Tuberculosis and Lung Diseases, Branch Rabka-Zdroj.
authors.forename: Henryk
authors.initials: H
authors.lastname: Mazurek
mesh_terms: D000328:Adult; D003550:Cystic Fibrosis / Q000523:psychology* / Q000628:therapy; D005260:Female; D006801:Humans; D016040:Lung Transplantation; D008297:Male; D011788:Quality of Life; D011795:Surveys and Questionnaires; D055815:Young Adult