title: Survival of chick embryo sympathetic neurons in cell culture.
abstract: Changes in neuronal numbers during the development of the chick embryo paravertebral sympathetic nervous system have been examined using cell culture techniques. Early sympathetic ganglia contain predominantly cells having neuronal phenotypes and these increase in number until embryonic day 9. Subsequently there is a large decrease in the number of neurons and an increase in the population of non-neuronal cells. This in vivo pattern is maintained when the neurons are grown in vitro, where Nerve Growth Factor more readily prevents the death of neurons cultured from 12-day or older embryos than those from earlier stages of development.
authors.affiliation: Queensland Institute of Medical Research and Biochemistry Department, Queensland University, Brisbane, Australia.
authors.forename: J
authors.initials: J
authors.lastname: Leah
authors.forename: C
authors.initials: C
authors.lastname: Kidson