title: Pre and post lipocryolysis thermic conditioning enhances rat adipocyte destruction.
abstract: BACKGROUND
  New knowledge about crystallization vs. lipid-to-gel transition has surfaced recently, since some of the latest publications on lipocryolysis have focused on its action mechanism. As a result, new opportunities for technical improvements and clinical outcome optimization have opened up. The food industry has been working with lipid crystal polymorphisms for decades, and tempering seems to be the easiest method of external conditioning, in addition to being harmless.
  
  
  OBJECTIVE
  Evaluate if pre and post lipocryolyisis thermic conditioning enhances rat adipocyte destruction.
  
  
  METHODS
  Several temperature treatment patterns (TTP) were applied to isolated rat adipocytes. The survival of the adipocytes exposed to the different TTPs and the formation of crystals in the surviving adipocytes were assessed and analyzed.
  
  
  RESULTS
  Pre and post lipocryolysis thermic conditioning changed lipocryolyisis crystallization process and showed an enhancement in adipocyte destruction that could represent an important step in improving clinical results.
  
  
  CONCLUSIONS
  pre and post lipocryolyisis thermic conditioning enhances rat adipocyte destruction.
authors.affiliation: Instituto de Investigaciones para las Especialidades Esteticas y del Envejecimiento, Barcelona. info@i2e3.com).
authors.forename: Hermán
authors.initials: H
authors.lastname: Pinto
authors.affiliation: Centre de Recerca en Metabolisme, Barcelona (CEREMET).
authors.forename: David
authors.initials: D
authors.lastname: Ricart-Jané
authors.affiliation: Centre de Recerca en Metabolisme, Barcelona (CEREMET).
authors.forename: Eva
authors.initials: E
authors.lastname: Pardina
mesh_terms: D017667:Adipocytes / Q000737:chemistry / Q000166:cytology*; D052436:Adipose Tissue, White / Q000737:chemistry / Q000166:cytology*; D000818:Animals; D016923:Cell Death; D002470:Cell Survival; D003080:Cold Temperature; D003460:Crystallization; D006358:Hot Temperature; D008297:Male; D008563:Membrane Lipids / Q000737:chemistry*; D044367:Phase Transition; D061251:Primary Cell Culture; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D008563:Membrane Lipids