title: The biomolecular era for thoracic surgeons: the example of the ESTS Biology Club.
abstract: Understanding basic mechanisms of lung disease may help to move forward the management of our patients. Molecular biology has affected our diagnostic and therapeutic pathways in the direction of personalized medicine not only for thoracic malignancies. Accordingly, thoracic surgeons are becoming increasingly aware that specific knowledge of genetic and epigenetic alterations may influence their clinical behavior-from the ward to the operating room (OR). In this continuously evolving scenario, surgical societies have perceived the increasing relevance of biomolecular medicine in the practice of modern thoracic surgery. More recently, in the spirit of mutual collaboration between sister societies, the European Society of Thoracic Surgeons (ESTS) has adopted the concept of the American Association for Thoracic Surgery (AATS) incorporating one session dedicated to the Biology Club within the Annual Meeting Program. The aim of the ESTS Biology Club is to outline and sponsor the new profile of the surgeon scientist during the only world meeting exclusively focused on general thoracic surgery. The following article will summarize the significance of this and give an update on molecular biology tools for thoracic malignancies.
authors.affiliation: 1 Division of Thoracic Surgery, University Hospital Zurich, Switzerland ; 2 Division of Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, USA ; 3 Department of Thoracic Surgery and Oncology, Istituto Nazionale Tumori, Fondazione Pascale, IRCCS, Naples, Italy.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Opitz
authors.affiliation: 1 Division of Thoracic Surgery, University Hospital Zurich, Switzerland ; 2 Division of Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, USA ; 3 Department of Thoracic Surgery and Oncology, Istituto Nazionale Tumori, Fondazione Pascale, IRCCS, Naples, Italy.
authors.forename: Thomas A
authors.initials: TA
authors.lastname: D'Amico
authors.affiliation: 1 Division of Thoracic Surgery, University Hospital Zurich, Switzerland ; 2 Division of Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, USA ; 3 Department of Thoracic Surgery and Oncology, Istituto Nazionale Tumori, Fondazione Pascale, IRCCS, Naples, Italy.
authors.forename: Gaetano
authors.initials: G
authors.lastname: Rocco
keywords: Molecular biology; mesothelioma; non-small cell lung cancer (NSCLC); the European Society of Thoracic Surgeons (ESTS); thoracic surgery