title: Prevalence of latent tuberculosis and treatment adherence among patients with chronic kidney disease in Campo Grande, State of Mato Grosso do Sul.
abstract: BACKGROUND
  The primary strategy for tuberculosis control involves identifying individuals with latent tuberculosis. This study aimed to estimate the prevalence of latent tuberculosis in chronic kidney disease (CKD) patients who were undergoing hemodialysis in Campo Grande, State of Mato Grosso do Sul, Brazil, to characterize the sociodemographic and clinical profiles of patients with latent tuberculosis, to verify the association between sociodemographic and clinical characteristics and the occurrence of latent tuberculosis, and to monitor patient adherence to latent tuberculosis treatment.
  
  
  METHODS
  This epidemiological study involved 418 CKD patients who were undergoing hemodialysis and who underwent a tuberculin skin test.
  
  
  RESULTS
  The prevalence of latent tuberculosis was 10.3%. The mean patient age was 53.43±14.97 years, and the patients were predominantly men (63.9%). The population was primarily Caucasian (58.6%); half (50%) were married, and 49.8% had incomplete primary educations. Previous contact with tuberculosis patients was reported by 80% of the participants. Treatment adherence was 97.7%.
  
  
  CONCLUSIONS
  We conclude that the prevalence of latent tuberculosis in our study population was low. Previous contact with patients with active tuberculosis increased the occurrence of latent infection. Although treatment adherence was high in this study, it is crucial to monitor tuberculosis treatment administered to patients in health services to maintain this high rate.
authors.affiliation: Programa de Pós-Graduação em Saúde e Desenvolvimento na Região Centro-Oeste, Universidade Federal do Mato Grosso do Sul, Campo Grande, MS, Brazi.
authors.forename: Aucely Corrêa Fernandes
authors.initials: AC
authors.lastname: Chagas
authors.affiliation: Programa de Pós-Graduação em Saúde e Desenvolvimento na Região Centro-Oeste, Universidade Federal do Mato Grosso do Sul, Campo Grande, MS, Brazi.
authors.forename: Günter
authors.initials: G
authors.lastname: Hans Filho
authors.affiliation: Faculdade de Medicina, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazi.
authors.forename: Sandra Maria do Valle Leone
authors.initials: SM
authors.lastname: de  Oliveira
authors.affiliation: Programa de Pós-Graduação em Saúde e Desenvolvimento na Região Centro-Oeste, Universidade Federal do Mato Grosso do Sul, Campo Grande, MS, Brazi.
authors.forename: Maria Lúcia
authors.initials: ML
authors.lastname: Ivo
authors.affiliation: Faculdade de Medicina Veterinária e Ciência Animal, Universidade Federal do Mato Grosso do Sul, Campo Grande, MS, Brazi.
authors.forename: Ruy Alberto Caetano
authors.initials: RA
authors.lastname: Corrêa Filho
authors.affiliation: Hospital Universitário Maria Aparecida Pedrossian, Universidade Federal do Mato Grosso do Sul, Campo Grande, MS, Brazi.
authors.forename: Maria Ilizabeth
authors.initials: MI
authors.lastname: Donatti
mesh_terms: D000328:Adult; D000368:Aged; D001938:Brazil / Q000453:epidemiology; D005260:Female; D006801:Humans; D055985:Latent Tuberculosis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance / Q000706:statistics & numerical data*; D015995:Prevalence; D006435:Renal Dialysis; D051436:Renal Insufficiency, Chronic / Q000150:complications* / Q000628:therapy; D012959:Socioeconomic Factors; D014374:Tuberculin Test; D055815:Young Adult