title: Posterior reversible encephalopathy syndrome in a patient of organophosphate poisoning.
abstract: A 32-year-old male presented with a history of consuming some organophosphorous compound with suicidal intention. He was treated with atropine, pralidoxime, ventilator support. During stay patient had persistent irritability, tachycardiaand hypertension despite sedation and labetalol infusion. He developed headache, visual blurring hemiparesis and focal seizures. Magnetic resonance imaging of the brain revealed multifocal hyperintensities mainly in subcortical areas of parietal and occipital regions in T2-weighted images, with increased values of Apparent Diffusion Coefficient, suggesting posterior reversible encephalopathy syndrome (PRES). The possibilities of PRES caused by organophosphorous poisoning either due to hypertension caused by autonomic deregulation or direct neurological toxicity has been discussed.
authors.affiliation: Lifeline24 × 7Intensive Care Unit, Hubli, Karnataka, India.
authors.forename: Rajesh
authors.initials: R
authors.lastname: Phatake
authors.affiliation: Department of Anesthesiology, SDM Medical College Hospital, Dharwar, India.
authors.forename: Sameer
authors.initials: S
authors.lastname: Desai
authors.affiliation: Lifeline24 × 7Intensive Care Unit, Hubli, Karnataka, India.
authors.forename: Manikanth
authors.initials: M
authors.lastname: Lodaya
authors.affiliation: Lifeline24 × 7Intensive Care Unit, Hubli, Karnataka, India.
authors.forename: Shrinivas
authors.initials: S
authors.lastname: Deshpande
authors.affiliation: Lifeline24 × 7Intensive Care Unit, Hubli, Karnataka, India.
authors.forename: Nagaraj
authors.initials: N
authors.lastname: Tankasali
keywords: Organophosphorous poisoning; poisoning; posterior reversible encephalopathy syndrome