title: Copper-catalyzed 5-endo-trig cyclization of ketoxime carboxylates: a facile synthesis of 2-arylpyrroles.
abstract: A novel and facile copper-catalyzed 5-endo-trig cyclization of ketoxime carboxylates for the synthesis of 2-arylpyrroles has been developed. The reaction tolerates a range of functional groups and is a practical procedure for rapid synthesis of 2-arylpyrroles in high yields under mild conditions.
authors.affiliation: Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry & Materials Science, Northwest University, Xi'an 710069, P. R. China. guanzhh@nwu.edu.cn.
authors.forename: Wei
authors.initials: W
authors.lastname: Du
authors.forename: Mi-Na
authors.initials: MN
authors.lastname: Zhao
authors.forename: Zhi-Hui
authors.initials: ZH
authors.lastname: Ren
authors.forename: Yao-Yu
authors.initials: YY
authors.lastname: Wang
authors.forename: Zheng-Hui
authors.initials: ZH
authors.lastname: Guan
mesh_terms: D002264:Carboxylic Acids / Q000737:chemistry* / Q000378:metabolism; D002384:Catalysis; D003300:Copper / Q000737:chemistry* / Q000378:metabolism; D003500:Cyclization; D010091:Oximes / Q000737:chemistry* / Q000378:metabolism; D011758:Pyrroles / Q000138:chemical synthesis* / Q000378:metabolism
chemical_list: D002264:Carboxylic Acids; D010091:Oximes; D011758:Pyrroles; D003300:Copper