title: Clinical and optic coherence tomography findings of focal choroidal excavation in Chinese patients.
abstract: BACKGROUND
  To describe the clinical and optical coherence tomography (OCT) features of focal choroidal excavation in Chinese patients.
  
  
  METHODS
  Retrospectively, thirty-seven eyes (in 31 patients) that demonstrated focal choroidal excavation on spectral-domain OCT were collected. Their clinical characteristics and other features were also collected and analyzed.
  
  
  RESULTS
  In total, 42 focal choroidal excavations were identified in 31 patients, including 25 unilateral and 6 bilateral (37 eyes). The abnormal changes in these eyes with choroidal excavation were more prominent at the outer part of the neuro-retina, the retinal pigment epithelium (RPE) and the choroid. The average transverse diameter and depth of the excavations were 670.8 μm and 106.9 μm, respectively. In addition to the conforming and nonconforming types, the excavations could also be classified into 2 types according to their shape: type 1 - small with a sharp, cut-down contour; and type 2 - slightly larger with a gradual edge. The transverse diameter/depth ratio of the two types were significantly different (type1: 4.57 ± 1.65, type 2: 10.0 ± 5.2; p = 0.000). Four central serous chorioretinopathy (CSCR) cases were confirmed by fluorescein angiography; in these cases, the retinal detachment was larger than the area of excavation, and the inner segment/outer segment (IS/OS) and external limiting membrane (ELM) were above those of the normal part. Concomitant CNV was also found in another 2 cases.
  
  
  CONCLUSIONS
  Focal choroidal excavation was not uncommon in Chinese patients. The choroid and the RPE at the excavation were impaired or vulnerable to other damage. Additionally, OCT might be useful in the differentiation between nonconforming excavations and ones with CSCR.
authors.forename: Jie
authors.initials: J
authors.lastname: Guo
authors.forename: Lu
authors.initials: L
authors.lastname: Zhong
authors.affiliation: Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Fenyang Road No, 83, Shanghai 200031, China. chhjiang70@163.com.
authors.forename: Chunhui
authors.initials: C
authors.lastname: Jiang
authors.forename: Xin
authors.initials: X
authors.lastname: Zhou
authors.forename: Gezhi
authors.initials: G
authors.lastname: Xu
authors.forename: Wenji
authors.initials: W
authors.lastname: Wang
authors.forename: Yuliang
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D002829:Choroid / Q000002:abnormalities* / Q000473:pathology; D015862:Choroid Diseases / Q000175:diagnosis* / Q000453:epidemiology; D005124:Eye Abnormalities / Q000175:diagnosis* / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods*; D055815:Young Adult