title: "En-face" spectral-domain optical coherence tomography findings in multiple evanescent white dot syndrome.
abstract: Purpose. The recent use of "en-face" enhanced-depth imaging spectral-domain optical coherence tomography (EDI SD-OCT) helps distinguish the retinal layers involved in the physiopathology of multiple evanescent white dot syndrome (MEWDS). Methods. Four patients presenting with MEWDS underwent a comprehensive ocular examination including C-scan ("en-face") EDI SD-OCT at the initial visit and during follow-up. Results. C-scans combined with the other multimodal imaging enabled the visualization of retinal damage. Acute lesions appeared as diffuse and focal disruptions occurring in the ellipsoid and interdigitation zones. The match between autofluorescence imaging, indocyanine green angiography, and "en-face" OCT helped identify the acute microstructural damages in the outer retina further than the choroid. Follow-up using "en-face" EDI-OCT revealed progressive and complete recovery of the central outer retinal layers. Conclusion. "En-face" EDI SD-OCT identified the site of initial damage in MEWDS as the photoreceptors and the interdigitation layers rather than the choroid. Moreover, "en-face" OCT is helpful in the follow-up of these lesions by being able to show the recovery of the outer retinal layers.
authors.affiliation: Department of Ophthalmology, Croix-Rousse University Hospital, Hospices Civils de Lyon, University of Medicine Lyon 1, 103 Grande rue de la Croix Rousse, 69317 Lyon Cedex 04, France.
authors.forename: Flore
authors.initials: F
authors.lastname: De Bats
authors.affiliation: Professor Sahel Department, Rothschild Ophthalmologic Foundation, 25 rue Manin, 75019 Paris, France ; Kleber Retinal Center, 50 Cours Franklin Roosevelt, 69006 Lyon, France.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Wolff
authors.affiliation: Professor Sahel Department, Rothschild Ophthalmologic Foundation, 25 rue Manin, 75019 Paris, France.
authors.forename: Vivien
authors.initials: V
authors.lastname: Vasseur
authors.affiliation: Professor Sahel Department, Rothschild Ophthalmologic Foundation, 25 rue Manin, 75019 Paris, France.
authors.forename: Aude
authors.initials: A
authors.lastname: Affortit
authors.affiliation: Department of Ophthalmology, Croix-Rousse University Hospital, Hospices Civils de Lyon, University of Medicine Lyon 1, 103 Grande rue de la Croix Rousse, 69317 Lyon Cedex 04, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Kodjikian
authors.affiliation: Professor Sahel Department, Rothschild Ophthalmologic Foundation, 25 rue Manin, 75019 Paris, France.
authors.forename: José-Alain
authors.initials: JA
authors.lastname: Sahel
authors.affiliation: Professor Sahel Department, Rothschild Ophthalmologic Foundation, 25 rue Manin, 75019 Paris, France ; Kleber Retinal Center, 50 Cours Franklin Roosevelt, 69006 Lyon, France ; Monticelli Paradis Retinal Center, 88 rue du Commandant Rolland, 13008 Marseille, France.
authors.forename: Martine
authors.initials: M
authors.lastname: Mauget-Faÿsse