title: DBAASP: database of antimicrobial activity and structure of peptides.
abstract: The Database of Antimicrobial Activity and Structure of Peptides (DBAASP) is a manually curated database for those peptides for which antimicrobial activity against particular targets has been evaluated experimentally. The database is a depository of complete information on: the chemical structure of peptides; target species; target object of cell; peptide antimicrobial/haemolytic/cytotoxic activities; and experimental conditions at which activities were estimated. The DBAASP search page allows the user to search peptides according to their structural characteristics, complexity type (monomer, dimer and two-peptide), source, synthesis type (ribosomal, nonribosomal and synthetic) and target species. The database prediction algorithm provides a tool for rational design of new antimicrobial peptides. DBAASP is accessible at http://www.biomedicine.org.ge/dbaasp/.
authors.affiliation: Laboratory of Bioinformatics, Ivane Beritashvili Center of Experimental Biomedicine, Tbilisi, Georgia.
authors.forename: Giorgi
authors.initials: G
authors.lastname: Gogoladze
authors.forename: Maia
authors.initials: M
authors.lastname: Grigolava
authors.forename: Boris
authors.initials: B
authors.lastname: Vishnepolsky
authors.forename: Mindia
authors.initials: M
authors.lastname: Chubinidze
authors.forename: Patrice
authors.initials: P
authors.lastname: Duroux
authors.forename: Marie-Paule
authors.initials: MP
authors.lastname: Lefranc
authors.forename: Malak
authors.initials: M
authors.lastname: Pirtskhalava
mesh_terms: D000465:Algorithms; D000890:Anti-Infective Agents / Q000737:chemistry*; D023181:Antimicrobial Cationic Peptides / Q000737:chemistry*; D016208:Databases, Factual; D010455:Peptides / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D023181:Antimicrobial Cationic Peptides; D010455:Peptides
keywords: antimicrobial activity; antimicrobial peptide; database; haemolytic/cytotoxic activity