title: Performance-enhancing methods for Au film over nanosphere surface-enhanced Raman scattering substrate and melamine detection application.
abstract: A new high-performance surface-enhanced Raman scattering (SERS) substrate with extremely high SERS activity was produced. This SERS substrate combines the advantages of Au film over nanosphere (AuFON) substrate and Ag nanoparticles (AgNPs). A three order enhancement of SERS was observed when Rhodamine 6G (R6G) was used as a probe molecule to compare the SERS effects of the new substrate and commonly used AuFON substrate. These new SERS substrates can detect R6G down to 1 nM. The new substrate was also utilized to detect melamine, and the limit of detection (LOD) is 1 ppb. A linear relationship was also observed between the SERS intensity at Raman peak 682 cm(-1) and the logarithm of melamine concentrations ranging from 10 ppm to 1 ppb. This ultrasensitive SERS substrate is a promising tool for detecting trace chemical molecules because of its simple and effective fabrication procedure, high sensitivity and high reproducibility of the SERS effect.
authors.affiliation: College of Mechatronics and Automation, National University of Defense Technology, Changsha, Hunan, P. R. China; State Key Laboratory of Transducer Technology, Chinese Academy of Science, Shanghai, P. R. China.
authors.forename: Jun Feng
authors.initials: JF
authors.lastname: Wang
authors.affiliation: College of Mechatronics and Automation, National University of Defense Technology, Changsha, Hunan, P. R. China.
authors.forename: Xue Zhong
authors.initials: XZ
authors.lastname: Wu
authors.affiliation: Beijing Institute of Radiation Medicine, Beijing, P. R. China.
authors.forename: Rui
authors.initials: R
authors.lastname: Xiao
authors.affiliation: College of Mechatronics and Automation, National University of Defense Technology, Changsha, Hunan, P. R. China; State Key Laboratory of Transducer Technology, Chinese Academy of Science, Shanghai, P. R. China.
authors.forename: Pei Tao
authors.initials: PT
authors.lastname: Dong
authors.affiliation: College of Mechatronics and Automation, National University of Defense Technology, Changsha, Hunan, P. R. China.
authors.forename: Chao Guang
authors.initials: CG
authors.lastname: Wang
mesh_terms: D003102:Colloids; D006046:Gold / Q000737:chemistry; D053768:Metal Nanoparticles / Q000648:ultrastructure; D054118:Nanospheres / Q000737:chemistry* / Q000648:ultrastructure; D012235:Rhodamines / Q000032:analysis; D012834:Silver / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet; D013059:Spectrum Analysis, Raman; D014227:Triazines / Q000032:analysis*
chemical_list: D003102:Colloids; D012235:Rhodamines; D014227:Triazines; C026188:rhodamine 6G; D012834:Silver; D006046:Gold; C011907:melamine