title: Systematic review of noninvasive treatments to arrest dentin non-cavitated caries lesions.
abstract: OBJECTIVE
  To systematically review the literature on the efficacy of noninvasive methods of arresting the progression of non-cavitated occlusal carious lesions in dentin.
  
  
  METHODS
  The Medline/PubMed, LILACS, SciELO and Scopus databases were searched to identify relevant publications through to November 2013. Only clinical trials evaluating the ability of noninvasive methods to arrest the progression of occlusal non-cavitated carious lesions in dentin were included. Screening, data extraction and quality assessment were conducted independently and in duplicate.
  
  
  RESULTS
  Of 167 citations identified, nine full text articles were screened and five were included in the analysis. All papers reported on occlusal fissure sealing using a self-curing glass ionomer (n = 1) or resin-based (n = 4) sealant. Only the use of resin-based sealant to obliterate occlusal fissures arrested the progression of non-cavitated occlusal carious lesions in dentin.
  
  
  CONCLUSIONS
  Occlusal fissure sealing with a resin-based sealant may arrest the progression of non-cavitated occlusal dentinal caries. Further clinical trials with longer follow-up times should be performed to increase scientific evidence.
authors.affiliation: Isauremi Vieira de Assunção, Giovanna de Fátima Alves da Costa, Boniek Castillo Dutra Borges, Department of Dentistry, Federal University of Rio Grande do Norte, Natal, 59056-000, Brazil.
authors.forename: Isauremi Vieira
authors.initials: IV
authors.lastname: de Assunção
authors.affiliation: Isauremi Vieira de Assunção, Giovanna de Fátima Alves da Costa, Boniek Castillo Dutra Borges, Department of Dentistry, Federal University of Rio Grande do Norte, Natal, 59056-000, Brazil.
authors.forename: Giovanna de Fátima Alves
authors.initials: Gde F
authors.lastname: da Costa
authors.affiliation: Isauremi Vieira de Assunção, Giovanna de Fátima Alves da Costa, Boniek Castillo Dutra Borges, Department of Dentistry, Federal University of Rio Grande do Norte, Natal, 59056-000, Brazil.
authors.forename: Boniek Castillo Dutra
authors.initials: BC
authors.lastname: Borges
keywords: Dental caries; Dental restoration; Dentin; Fissure sealants; Preventive therapy