title: Cargo recognition and trafficking in selective autophagy.
abstract: Selective autophagy is a quality control pathway through which cellular components are sequestered into double-membrane vesicles and delivered to specific intracellular compartments. This process requires autophagy receptors that link cargo to growing autophagosomal membranes. Selective autophagy is also implicated in various membrane trafficking events. Here we discuss the current view on how cargo selection and transport are achieved during selective autophagy, and point out molecular mechanisms that are congruent between autophagy and vesicle trafficking pathways.
authors.affiliation: Institute of Biochemistry II, Goethe University, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Stolz
authors.affiliation: Institute of Biochemistry II, Goethe University, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Ernst
authors.affiliation: 1] Institute of Biochemistry II, Goethe University, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany [2] Buchmann Institute for Molecular Life Sciences, Max-von-Laue-Straße 15, D-60438 Frankfurt am Main, Germany.
authors.forename: Ivan
authors.initials: I
authors.lastname: Dikic
mesh_terms: D000818:Animals; D001343:Autophagy; D006801:Humans; D007425:Intracellular Membranes / Q000378:metabolism*; D021381:Protein Transport; D018160:Receptors, Cytoplasmic and Nuclear / Q000378:metabolism; D022161:Transport Vesicles / Q000378:metabolism*
chemical_list: D018160:Receptors, Cytoplasmic and Nuclear