title: Attitudes toward pharmacological cognitive enhancement-a review.
abstract: A primary means for the augmentation of cognitive brain functions is "pharmacological cognitive enhancement" (PCE). The term usually refers to the off-label use of medical substances to improve mental performance in healthy individuals. With the final aim to advance the normative debate taking place on that topic, several empirical studies have been conducted to assess the attitudes toward PCE in the public, i.e., in groups outside of the academic debate. In this review, we provide an overview of the 40 empirical studies published so far, reporting both their methodology and results. Overall, we find that several concerns about the use of PCE are prevalent in the public. These concerns largely match those discussed in the normative academic debate. We present our findings structured around the three most common concerns: medical safety, coercion, and fairness. Fairness is divided into three subthemes: equality of opportunity, honesty, and authenticity. Attitudes regarding some concerns are coherent across studies (e.g., coercion), whereas for others we find mixed results (e.g., authenticity). Moreover, we find differences in how specific groups-such as users, nonusers, students, parents, and health care providers-perceive PCE: a coherent finding is that nonusers display more concerns regarding medical safety and fairness than users. We discuss potential psychological explanations for these differences.
authors.affiliation: Department of Industrial Design, Eindhoven University of Technology Eindhoven, Netherlands.
authors.forename: Kimberly J
authors.initials: KJ
authors.lastname: Schelle
authors.affiliation: Department of Experimental Psychology, University of Oxford Oxford, UK ; Department of Values, Technology and Innovation, Delft University of Technology Delft, Netherlands.
authors.forename: Nadira
authors.initials: N
authors.lastname: Faulmüller
authors.affiliation: Department of Experimental Psychology, University of Oxford Oxford, UK.
authors.forename: Lucius
authors.initials: L
authors.lastname: Caviola
authors.affiliation: Department of Experimental Psychology, University of Oxford Oxford, UK.
authors.forename: Miles
authors.initials: M
authors.lastname: Hewstone
keywords: authenticity; brain function augmentation; coercion; cognitive enhancement; fairness; medical safety; neuroenhancement; smart drugs