title: Diprenylated Indole Alkaloids from Fruits of Hexalobus monopetalus.
abstract: New hexalobine type alkaloid, 5-(2″,3″-epoxy-3″-methylbutyl)-3-(3'-hydroxy-3'-methyl-1'-acetyloxy-but-2'-yl)indole (1) alongside the known hexalobines 3-(2',3'-dihydroxy-3'-methylbutyl)-5-(3″-methylcrotonoyl) indole (2), 3,5-hexalobine C (3) and 3,5-hexalobine D (4) were isolated from fruits of Hexalobus monopetalus. Compounds 3 and 4 exhibited antifungal activity against Candida albicans.
authors.affiliation: Department of Traditional Medicine Research, National Institute for Medical Research, P.O. Box 9653, Dar es Salaam, Tanzania.
authors.forename: Hamisi M
authors.initials: HM
authors.lastname: Malebo
authors.affiliation: Department of Chemistry, University of Dar es Salaam, P.O. Box 35061, Dar es Salaam, Tanzania.
authors.forename: Stephan A
authors.initials: SA
authors.lastname: Jonker
authors.affiliation: Department of Pharmaceutical Chemistry, Institute of Pharmacy, University of Erlangen, Schuhstrasse 19, 91052 Erlangen, Germany.
authors.forename: Reiner
authors.initials: R
authors.lastname: Waibel
authors.affiliation: Department of Chemistry, University of Dar es Salaam, P.O. Box 35061, Dar es Salaam, Tanzania.
authors.forename: Mayunga H H
authors.initials: MH
authors.lastname: Nkunya
keywords: Candida albicans; Hexalobines; Hexalobus monopetalus; Indole alkaloids