title: Patients' perception on the nutritional therapy for diabetic nephropathy.
abstract: Low protein diet (LPD) plays an important role in preventing the progression of diabetic nephropathy. However, it is a great burden to the patients. In this paper, we have studied the quality of life (QOL) in such patients. The study subjects were 59 patients (male 38, female 21) with type 2 diabetes. The patients were classified into tertiles based on their protein intake (g/kg BW). Scores from the diet-related QOL questionnaire were summarized by principal component analysis into four components; mental health, less burden, satisfaction and merit, and less social restriction. Higher protein intake was associated with less burden and less social restriction. In multiple regression analysis, the significant predictors for the "less burden" component were higher protein intake/BW and estimated glomerular filtration rate (eGFR). In summary, registered dietitians and clinicians must keep in mind that LPD is a serious burden to the patients and efforts must be made to minimize their burden in order to avoid discontinuation.
authors.affiliation: Department of Metabolism and Clinical Nutrition, Kyoto University Hospital, Kyoto, Japan.
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Shide
authors.affiliation: Department of Food and Nutrition, Kyoto Women's University, Kyoto, Japan.
authors.forename: Yuka
authors.initials: Y
authors.lastname: Takada
authors.affiliation: Department of Food and Nutrition, Kyoto Women's University, Kyoto, Japan.
authors.forename: Asuka
authors.initials: A
authors.lastname: Nakashima
authors.affiliation: Department of Metabolism and Clinical Nutrition, Kyoto University Hospital, Kyoto, Japan.
authors.forename: Hidemi
authors.initials: H
authors.lastname: Tsuji
authors.affiliation: Department of Metabolism and Clinical Nutrition, Kyoto University Hospital, Kyoto, Japan.
authors.forename: Keiko
authors.initials: K
authors.lastname: Wada
authors.affiliation: Department of Health and Nutrition, Osaka Shoin Women's University, Osaka, Japan.
authors.forename: Akiko
authors.initials: A
authors.lastname: Kuwabara
authors.affiliation: Department of Food and Nutrition, Kyoto Women's University, Kyoto, Japan.
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Tanaka
authors.affiliation: Department of Diabetes, Endocrinology, and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors.forename: Nobuya
authors.initials: N
authors.lastname: Inagaki
keywords: diabetic nephropathy; low protein diet; quality of life (QOL)