title: Does aerobic exercise training promote changes in structural and biomechanical properties of the tendons in experimental animals? A systematic review.
abstract: To develop a systematic review to evaluate, through the best scientific evidence available, the effectiveness of aerobic exercise in improving the biomechanical characteristics of tendons in experimental animals. Two independent assessors conducted a systematic search in the databases Medline/PUBMED and Lilacs/BIREME, using the following descriptors of Mesh in animal models. The ultimate load of traction and the elastic modulus tendon were used as primary outcomes and transverse section area, ultimate stress and tendon strain as secondary outcomes. The assessment of risk of bias in the studies was carried out using the following methodological components: light/dark cycle, temperature, nutrition, housing, research undertaken in conjunction with an ethics committee, randomization, adaptation of the animals to the training and preparation for the mechanical test. Eight studies, comprising 384 animals, were selected; it was not possible to combine them into one meta-analysis due to the heterogeneity of the samples. There was a trend to increasing ultimate load without changes in the other outcomes studied. Only one study met more than 80% of the quality criteria. Physical training performed in a structured way with imposition of overloads seems to be able to promote changes in tendon structure of experimental models by increasing the ultimate load supported. However, the results of the influence of exercise on the elastic modulus parameters, strain, transverse section area and ultimate stress, remain controversial and inconclusive. Such a conclusion must be evaluated with reservation as there was low methodological control in the studies included in this review.
authors.affiliation: Master in Physiotherapy. Federal University of Pernambuco - UFPE, Brazil.
authors.forename: M A
authors.initials: MA
authors.lastname: Bezerra
authors.affiliation: Physiotherapy Department of the Federal University of Pernambuco - UFPE, Brazil.
authors.forename: A
authors.initials: A
authors.lastname: Lemos
authors.affiliation: Master in Physiotherapy. Federal University of Pernambuco - UFPE, Brazil.
authors.forename: K D S
authors.initials: KD
authors.lastname: Lira
authors.affiliation: Master in Physiotherapy. Federal University of Pernambuco - UFPE, Brazil.
authors.forename: P V C
authors.initials: PV
authors.lastname: Silveira
authors.affiliation: Federal University of Pernambuco - UFPE, Brazil.
authors.forename: M P G
authors.initials: MP
authors.lastname: Coutinho
authors.affiliation: Anatomy Department of the Federal University of Pernambuco - UFPE, Brazil.
authors.forename: S R A
authors.initials: SR
authors.lastname: E Moraes
keywords: aerobic exercise; animals; biomechanics; systematic reviews