title: Tumor archaeology: tracking leukemic evolution to its origins.
abstract: Unearthing of the BRAF mutation in self-renewing hematopoietic stem cells reveals an unexpected origin for hairy cell leukemia-a mature B cell malignancy-and a potential new therapeutic target (Chung et al., this issue).
authors.affiliation: Princess Margaret Cancer Centre, University Health Network and Department of Molecular Genetics, University of Toronto, Ontario M5G2C1, Canada.
authors.forename: John E
authors.initials: JE
authors.lastname: Dick
mesh_terms: D019143:Evolution, Molecular; D006801:Humans; D007938:Leukemia / Q000235:genetics* / Q000473:pathology; D008954:Models, Biological; D009154:Mutation