title: Two new lignans with antioxidative activities from Jatropha curcas.
abstract: Activity-guided isolation of dried seeds of Jatropha curcas L. led to the isolation of two new lignans along with eight known compounds. These compounds were determined by spectroscopic analysis to be jatrophasin C (1), jatrophasin D (2), β-sitosterol (3), jatrophasin A (4), daucosterol (5), isoamericanol A (6), ( ± )-3,3'-bisdemethylpinoresinol (7), 7'-epi-sesamin-dicatechol (8), isoprincepin (9) and americanol A (10), of which 1 and 2 were new compounds. The antioxidative activities along with peroxisome proliferator-activated receptor gamma exciting activity of these compounds were also determined.
authors.affiliation: a Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences, Shenzhen University , Shenzhen 518060 , P.R. China.
authors.forename: Xiaofan
authors.initials: X
authors.lastname: Li
authors.forename: Ling
authors.initials: L
authors.lastname: Li
authors.forename: Jue
authors.initials: J
authors.lastname: Wang
authors.forename: Tiejie
authors.initials: T
authors.lastname: Wang
authors.forename: Liyan
authors.initials: L
authors.lastname: Wang
mesh_terms: D031286:Jatropha / Q000737:chemistry*; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D047495:PPAR gamma / Q000187:drug effects; D012639:Seeds / Q000737:chemistry; D012855:Sitosterols / Q000737:chemistry
chemical_list: C572728:3,3'-bisdemethylpinoresinol; D017705:Lignans; D047495:PPAR gamma; D012855:Sitosterols; C000594523:jatrophasin C; C000594524:jatrophasin D; C025473:gamma-sitosterol
keywords: Euphorbiaceae; Jatropha curcas; antioxidative activity; lignan