title: Evidence of higher oxidative status in depression and anxiety.
abstract: We use a simple method for evaluating antioxidative status, by measuring the redox potential of urine, and correlate the findings with measures of anxiety and depression. We include 63 individuals (28 males and 35 females aged between 20 and 65 years). The validated anxiety State-Trait Anxiety Inventory questionnaire and the validated BDI (Beck Depression Inventory) questionnaire were used to evaluate anxiety and depression. Antioxidative status was determined by measuring the redox potential of urine collected in standard conditions. Correlation of the antioxidant capacity of urines evaluated using the ferric ion/specific dye method or through redox potential using the platinum electrode demonstrated the suitability of this last procedure. We found that normal anxiety state values corresponded to low urine redox potentials, whereas higher anxiety states were associated with high urinary redox potential. We also found that individuals with normal BDI values had significantly lower urine redox potentials than individuals with higher BDI values.
authors.affiliation: Psychology and Neurology Center (CLONUS), 07014 Palma de Mallorca, Spain ; Centro de Enseñanza Superior Alberta Giménez (CESAG), 07013 Palma de Mallorca, Spain.
authors.forename: G
authors.initials: G
authors.lastname: Grases
authors.affiliation: Psychology and Neurology Center (CLONUS), 07014 Palma de Mallorca, Spain.
authors.forename: M A
authors.initials: MA
authors.lastname: Colom
authors.affiliation: University Institute of Health Sciences Research (IUNICS-IdIsPa), University of Balearic Islands, 07122 Palma de Mallorca, Spain.
authors.forename: R A
authors.initials: RA
authors.lastname: Fernandez
authors.affiliation: University Institute of Health Sciences Research (IUNICS-IdIsPa), University of Balearic Islands, 07122 Palma de Mallorca, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Costa-Bauzá
authors.affiliation: University Institute of Health Sciences Research (IUNICS-IdIsPa), University of Balearic Islands, 07122 Palma de Mallorca, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Grases
mesh_terms: D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000378:metabolism; D001007:Anxiety / Q000378:metabolism* / Q000473:pathology; D003863:Depression / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D016877:Oxidants / Q000652:urine; D018384:Oxidative Stress; D011795:Surveys and Questionnaires
chemical_list: D000975:Antioxidants; D016877:Oxidants