title: Broad-spectrum antiviral property of polyoxometalate localized on a cell surface.
abstract: Cs2K4Na[SiW9Nb3O40] has broad antiviral ability including anti-Influenza A, -Influenza B, -HSV-1, -HSV-2, -HIV-1, and -HBV. A series of antivirus and/or biochemical experiments and X-ray nanotomography analysis confirm that this kind of broad-spectrum antiviral property is mainly due to its localization on the cell surface.
authors.affiliation: School of Public Health, Jilin University , Changchun, Jilin 130021, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Wang
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.forename: Kun
authors.initials: K
authors.lastname: Xu
authors.forename: Yanfei
authors.initials: Y
authors.lastname: Qi
authors.forename: Jun
authors.initials: J
authors.lastname: Zhong
authors.forename: Kai
authors.initials: K
authors.lastname: Zhang
authors.forename: Juan
authors.initials: J
authors.lastname: Li
authors.forename: Enbo
authors.initials: E
authors.lastname: Wang
authors.forename: Ziyu
authors.initials: Z
authors.lastname: Wu
authors.forename: Zhenhui
authors.initials: Z
authors.lastname: Kang
mesh_terms: D000998:Antiviral Agents / Q000737:chemistry* / Q000494:pharmacology; D056945:Hep G2 Cells / Q000737:chemistry / Q000821:virology; D006801:Humans; D013499:Surface Properties; D017973:Tungsten Compounds / Q000737:chemistry* / Q000494:pharmacology; D014780:Viruses / Q000187:drug effects*; D000099294:Polyoxometalates
chemical_list: D000998:Antiviral Agents; D017973:Tungsten Compounds; C102296:polyoxometalate I; D000099294:Polyoxometalates