title: Microwave-assisted preparation of nucleoside-phosphoramidites.
abstract: Microwave-assisted phosphitylation of sterically hindered nucleosides is demonstrated to be an efficient method for the preparation of corresponding phosphoramidites (otherwise onerous under standard conditions) and is shown to be general in its applicability.
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. rkrishna@scripps.edu.
authors.forename: G
authors.initials: G
authors.lastname: Meher
authors.forename: T
authors.initials: T
authors.lastname: Efthymiou
authors.forename: M
authors.initials: M
authors.lastname: Stoop
authors.forename: R
authors.initials: R
authors.lastname: Krishnamurthy
mesh_terms: D008872:Microwaves; D009705:Nucleosides / Q000138:chemical synthesis* / Q000528:radiation effects; D009943:Organophosphorus Compounds / Q000138:chemical synthesis* / Q000528:radiation effects
chemical_list: D009705:Nucleosides; D009943:Organophosphorus Compounds; C434331:phosphoramidite