title: Pseudoxanthoma elasticum and nephrocalcinosis: Incidental finding or an infrequent manifestation?
abstract: Pseudoxanthoma elasticum (PXE) is an inherited disorder characterized by generalized fragmentation and progressive calcification of elastic tissue. We report two sporadic cases of PXE, both of whom presented with asymptomatic yellowish papules over the flexural sites for cosmetic reasons. Histopathological findings on hematoxylin and eosin and Verhoeff-Van Gieson (VVG) staining were classical of PXE. In addition to this, renal calcification was documented on plain radiography of kidneys, ureters, and bladder (KUB) in both the cases. Paucity of literature describing the association of nephrocalcinosis with PXE prompted the present report.
authors.affiliation: Department of Dermatology, Medical College and Hospital, Kolkata, West Bengal, India.
authors.forename: Tirthankar
authors.initials: T
authors.lastname: Gayen
authors.affiliation: Department of Dermatology, Medical College and Hospital, Kolkata, West Bengal, India.
authors.forename: Anupam
authors.initials: A
authors.lastname: Das
authors.affiliation: Department of Dermatology, Medical College and Hospital, Kolkata, West Bengal, India.
authors.forename: Sudipta
authors.initials: S
authors.lastname: Roy
authors.affiliation: Department of Radiodiagnosis, Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, West Bengal, India.
authors.forename: Shamick
authors.initials: S
authors.lastname: Biswas
authors.affiliation: Department of Dermatology, Medical College and Hospital, Kolkata, West Bengal, India.
authors.forename: Kaushik
authors.initials: K
authors.lastname: Shome
authors.affiliation: Department of Dermatology, Medical College and Hospital, Kolkata, West Bengal, India.
authors.forename: Satyendra N
authors.initials: SN
authors.lastname: Chowdhury
keywords: Association; nephrocalcinosis; pseudoxanthoma elasticum