title: Severe Plasmodium knowlesi infection with multiorgan involvement in north east peninsular Malaysia.
abstract: Plasmodium knowlesi has been recently identified as the "fifth human malaria species" following the discovery in Malaysian Borneo of a large focus of this simian malaria parasite in humans. Even though it shares microscopic similarities with Plasmodium malariae, it may cause severe illness with risk of fatality. We describe a case of P. knowlesi infection causing multi-organ failure in a patient who was successfully managed due to early recognition of the infection. Clinicians in this region should be more aware of the infection as it is not as rare as previously thought. This case write up highlight the case of severe malaria infection which presented with multi organ involvement which is caused by P. knowlesi.
authors.affiliation: Department of Family Medicine, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia.
authors.forename: A K
authors.initials: AK
authors.lastname: Azidah
authors.affiliation: Department of Family Medicine, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia.
authors.forename: M A
authors.initials: MA
authors.lastname: Mohd Faizal
authors.affiliation: Department of Family Medicine, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia.
authors.forename: H Y
authors.initials: HY
authors.lastname: Lili
authors.affiliation: Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia.
authors.forename: M
authors.initials: M
authors.lastname: Zeehaida
mesh_terms: D000328:Adult; D000962:Antimalarials / Q000008:administration & dosage*; D004318:Doxycycline / Q000008:administration & dosage*; D006801:Humans; D008288:Malaria / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D008296:Malaysia; D008297:Male; D009102:Multiple Organ Failure / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D016790:Plasmodium knowlesi / Q000235:genetics / Q000302:isolation & purification*; D016896:Treatment Outcome
chemical_list: D000962:Antimalarials; D004318:Doxycycline