title: Intracellular gold nanoparticle aggregation and their potential applications in photodynamic therapy.
abstract: Gold nanoparticles (Au NPs) with opposite surface charge can form aggregates through electrostatic interaction and exhibit surface plasmon resonance (SPR) induced-localized electromagnetic (EM) field enhancement under light irradiation. Intracellular aggregation of Au NPs can further improve the therapeutic efficiency of Au NP-enhanced photodynamic therapy of cancer by promoting singlet oxygen generation.
authors.affiliation: Department of Chemistry, Chemical Biology and Biomedical Engineering, Stevens Institute of Technology, Castle Point on Hudson, Hoboken, NJ 07030, USA. Hongjun.Wang@stevens.edu.
authors.forename: Yamin
authors.initials: Y
authors.lastname: Yang
authors.forename: Yue
authors.initials: Y
authors.lastname: Hu
authors.forename: Henry
authors.initials: H
authors.lastname: Du
authors.forename: Hongjun
authors.initials: H
authors.lastname: Wang
mesh_terms: D004574:Electromagnetic Fields; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles; D010778:Photochemotherapy
chemical_list: D006046:Gold