title: Fracture analysis for biological materials with an expanded cohesive zone model.
abstract: In this study, a theoretical framework for simulation of fracture of bone and bone-like materials is provided. An expanded cohesive zone model with thermodynamically consistent framework has been proposed and used to investigate the crack growth resistance of bone and bone-like materials. The reversible elastic deformation, irreversible plastic deformation caused by large deformation of soft protein matrix, and damage evidenced by the material separation and crack nucleation in the cohesive zone, were all taken into account in the model. Furthermore, the key mechanisms in deformation of biocomposites consisting of mineral platelets and protein interfacial layers were incorporated in the fracture process zone in this model, thereby overcoming the limitations of previous cohesive zone modeling of bone fracture. Finally, applications to fracture of cortical bone and human dentin were presented, which showed good agreement between numerical simulation and reported experiments and substantiated the effectiveness of the model in investigating the fracture behavior of bone-like materials.
authors.affiliation: Department of Physics, Shanghai University, Shanghai 200444, China.
authors.forename: Bingbing
authors.initials: B
authors.lastname: An
authors.affiliation: Department of Physics, Shanghai University, Shanghai 200444, China.
authors.forename: Xinluo
authors.initials: X
authors.lastname: Zhao
authors.affiliation: Department of Mechanical Engineering, University of Maryland Baltimore County, Baltimore, MD 21250, USA.
authors.forename: Dwayne
authors.initials: D
authors.lastname: Arola
authors.affiliation: Department of Mechanics, Shanghai University, Shanghai 200444, China. Electronic address: donzhang@staff.shu.edu.cn.
authors.forename: Dongsheng
authors.initials: D
authors.lastname: Zhang
mesh_terms: D001696:Biomechanical Phenomena; D001698:Biomedical Engineering; D018786:Bone Substitutes / Q000737:chemistry*; D001842:Bone and Bones / Q000737:chemistry; D003198:Computer Simulation; D003804:Dentin / Q000737:chemistry*; D004548:Elasticity; D050723:Fractures, Bone / Q000503:physiopathology*; D006801:Humans; D008422:Materials Testing; D008962:Models, Theoretical; D010969:Plastics; D011312:Pressure; D011475:Prosthesis Failure; D013816:Thermodynamics
chemical_list: D018786:Bone Substitutes; D010969:Plastics
keywords: Bone; Cohesive zone model; Fracture; R-curve; Thermodynamic consistency