title: Perioperative outcome of esophageal fundoplication for gastroesophageal reflux disease in obese and morbidly obese patients.
abstract: BACKGROUND
  To determine the perioperative safety of esophageal fundoplication for gastroesophageal reflux disease (GERD) in patients with body mass index (BMI) ≥ 35 kg/m(2).
  
  
  METHODS
  A retrospective review of 4,231 patients who underwent fundoplication for GERD from 2005 to 2009 was performed. Patients were identified via National Surgical Quality Improvement Program and grouped by BMI < 35 versus BMI ≥ 35 kg/m(2). Univariate analysis compared 30-day outcomes.
  
  
  RESULTS
  Of the 4,231 patients, 3,496 (83%) had BMI < 35 kg/m(2) and 735 (17%) had BMI ≥ 35 kg/m(2). Mean BMI for each cohort was 27.9 versus 39.1, respectively. Patients with BMI ≥ 35 kg/m(2) had significantly longer operative times (129.7 vs 118 minutes, P < .0001) and increased American Society of Anesthesiologists scores (2.43 vs 2.3, P = .001). The overall complication rate was 1.96%. No difference was demonstrated by BMI in complication rate or hospital length of stay. Increased American Society of Anesthesiologists score, diabetes, black race, longer operative time, and intraoperative transfusion significantly increased postoperative complication rates.
  
  
  CONCLUSIONS
  No increased risk is conferred to morbidly obese patients who undergo fundoplication for GERD management. This study identified independent patient risk factors for postoperative complication following esophageal fundoplication.
authors.affiliation: Division of Laparoscopic, Bariatric and Advanced GI Surgery, Stony Brook University Medical Center, 100 Nichols Road, Stony Brook, NY 11794, USA. Electronic address: dana.telem@stonybrookmedicine.edu.
authors.forename: Dana A
authors.initials: DA
authors.lastname: Telem
authors.affiliation: Division of Laparoscopic, Bariatric and Advanced GI Surgery, Stony Brook University Medical Center, 100 Nichols Road, Stony Brook, NY 11794, USA.
authors.forename: Maria
authors.initials: M
authors.lastname: Altieri
authors.affiliation: Division of Laparoscopic, Bariatric and Advanced GI Surgery, Stony Brook University Medical Center, 100 Nichols Road, Stony Brook, NY 11794, USA.
authors.forename: Gerald
authors.initials: G
authors.lastname: Gracia
authors.affiliation: Division of Laparoscopic, Bariatric and Advanced GI Surgery, Stony Brook University Medical Center, 100 Nichols Road, Stony Brook, NY 11794, USA.
authors.forename: Aurora D
authors.initials: AD
authors.lastname: Pryor
mesh_terms: D015897:Comorbidity; D005260:Female; D018662:Fundoplication; D005764:Gastroesophageal Reflux / Q000453:epidemiology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology*; D009767:Obesity, Morbid / Q000453:epidemiology; D011183:Postoperative Complications / Q000453:epidemiology*; D012307:Risk Factors; D016896:Treatment Outcome
keywords: Complications; Fundoplication; Gastroesophageal reflux; Morbid obesity; Outcomes