title: Effects of partially ionised medical oxygen, especially with O2•-, in vibration white finger patients.
abstract: A major symptom of hand-arm vibration syndrome is a secondary Raynaud's phenomenon-vibration white finger (VWF)-which results from a vasospasm of the digital arteries caused by work with vibration devices leading to occupational disease. Pharmacotherapy of VWF is often ineffective or has adverse effects. The aim of this work was to verify the influence of inhalation of partially ionized oxygen (O2•-) on peripheral blood vessels in the hands of patients with VWF. Ninety one (91)patients with VWF underwent four-finger adsorption plethysmography, and the pulse wave amplitude was recorded expressed in numeric parameters-called the native record. Next, a cold water test was conducted following with second plethysmography. The patients were divided in to the three groups. First and second inhaled 20-min of ionized oxygen O2•- or oxygen O2 respectively. Thirth group was control without treatment. All three groups a follow-up third plethysmography-the post-therapy record. Changes in the pulse wave amplitudes were evaluated. Inpatients group inhaling O2•- a modest increase of pulse wave amplitude was observed compared to the native record; patients inhaling medical oxygen O2 and the control showed a undesirable decline of pulse wave amplitude in VWF fingers. Strong vasodilatation were more frequent in the group inhaling O2•- compare to O2 (p < 0.05). Peripheral vasodilatation achieved by inhalation of O2•- could be used for VWF treatment without undesirable side effect in hospital as well as at home environment.
authors.affiliation: Department of Occupational Medicine and Clinical Toxicology, Faculty of Medicine, Pavol Jozef Safarik University, 04190 Kosice, Slovak Republic. slavomir.perecinsky@upjs.sk.
authors.forename: Slavomír
authors.initials: S
authors.lastname: Perečinský
authors.affiliation: Department of Occupational Medicine and Clinical Toxicology, Faculty of Medicine, Pavol Jozef Safarik University, 04190 Kosice, Slovak Republic. murinovalenka@yahoo.com.
authors.forename: Lenka
authors.initials: L
authors.lastname: Murínová
authors.affiliation: Department of Human Physiology, Faculty of Medicine, Pavol Jozef Safarik University, 04001 Kosice, Slovak Republic. engler@io2th.com.
authors.forename: Ivan
authors.initials: I
authors.lastname: Engler
authors.affiliation: Department of Human Physiology, Faculty of Medicine, Pavol Jozef Safarik University, 04001 Kosice, Slovak Republic. viliam.donic@upjs.sk.
authors.forename: Viliam
authors.initials: V
authors.lastname: Donič
authors.affiliation: Cardiology Clinic, Faculty of Medicine, Pavol Jozef Safarik University, 04001 Košice, Slovak Republic. murinpavol@yahoo.com.
authors.forename: Pavol
authors.initials: P
authors.lastname: Murín
authors.affiliation: Department of Occupational Medicine and Clinical Toxicology, Faculty of Medicine, Pavol Jozef Safarik University, 04190 Kosice, Slovak Republic. marek.varga@upjs.sk.
authors.forename: Marek
authors.initials: M
authors.lastname: Varga
authors.affiliation: Department of Occupational Medicine and Clinical Toxicology, Faculty of Medicine, Pavol Jozef Safarik University, 04190 Kosice, Slovak Republic. lubomir.legath@upjs.sk.
authors.forename: Lubomír
authors.initials: L
authors.lastname: Legáth
mesh_terms: D000328:Adult; D000390:Air Ionization; D005260:Female; D053421:Hand-Arm Vibration Syndrome / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases; D010102:Oxygen Inhalation Therapy / Q000379:methods*; D011928:Raynaud Disease / Q000628:therapy; D014732:Vibration / Q000009:adverse effects*