title: [Influence of histological prostatitis on the clinical features of benign prostatic hyperplasia and prostate cancer].
abstract: OBJECTIVE
  To investigate the influence of histological prostatitis (HP) on the clinical features of benign prostatic hyperplasia (BPH) and prostate cancer (PCa) and its clinical significance.
  
  
  METHODS
  We retrospectively studied the data of 273 cases of BPH and 240 cases of PCa, including age, prostate volume, total prostatic special antigen (tPSA), prostatic special antigen density (PSAD), maximum urinary flow rate (MFR) and acute urinary retention (AUR).
  
  
  RESULTS
  Totally, 186 cases of BPH (68.13%) and 45 cases of PCa (18.75%) were complicated by HP, with statistically significant difference between the two groups (P < 0.05). Compared with the patients with BPH only, those complicated by HP showed significantly elevated tPSA, PSAD and total prostate volume (all P < 0.05), decreased MFR (P < 0.05) and increased risk of AUR (P < 0.05). There was no significant difference in the patients' age between the two groups (P > 0.05). The levels of tPSA and PSAD were remarkably higher in the PCa patients complicated by HP than in those with PCa only (all P < 0.05), but no significant differences were found in the other indexes between the two groups (P > 0.05).
  
  
  CONCLUSIONS
  HP may play a certain role in the progenesis and progression of HP and PCa, but HP is associated more closely with BPH.
authors.forename: Feng
authors.initials: F
authors.lastname: Zhang
authors.forename: A
authors.initials: A
authors.lastname: Si-Mu-Jiang-Abula
authors.forename: Li-Dong
authors.initials: LD
authors.lastname: Zhang
mesh_terms: D000368:Aged; D018450:Disease Progression; D006801:Humans; D008297:Male; D009929:Organ Size; D011467:Prostate / Q000473:pathology*; D017430:Prostate-Specific Antigen / Q000097:blood; D011470:Prostatic Hyperplasia / Q000209:etiology*; D011471:Prostatic Neoplasms / Q000150:complications*; D011472:Prostatitis / Q000150:complications*; D012189:Retrospective Studies; D016055:Urinary Retention / Q000209:etiology
chemical_list: D017430:Prostate-Specific Antigen