title: Polarity factors play a role in antibiotic resistance.
abstract: In this issue of Chemistry & Biology, Kirkpatrick and Viollier describe a new twist in the relationship between bacterial cell development and antibiotic resistance. They reveal that TipN, which orchestrates development at cell poles, is required to tolerate induced expression of an antibiotic efflux pump.
authors.affiliation: Department of Biochemistry and Molecular Biology, 929 E. 57(th) Street, University of Chicago, Chicago, IL 60637, USA. Electronic address: aretha@uchicago.edu.
authors.forename: Aretha
authors.initials: A
authors.lastname: Fiebig
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000378:metabolism*; D016935:Caulobacter crescentus / Q000187:drug effects*; D016764:Cell Polarity / Q000187:drug effects*; D002939:Ciprofloxacin / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial / Q000187:drug effects*; D009268:Nalidixic Acid / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D009268:Nalidixic Acid; D002939:Ciprofloxacin