title: Paraneoplastic granulocytosis in an advanced lung cancer patient.
abstract: Paraneoplastic syndromes (PNPs) refer to cancer-associated signs and symptoms arising in organs and tissues that are remote from the cancer and unrelated to metastasis. Currently the best described PNPs are attributed to tumor secretion of functional peptides and hormones or immune cross-reactivity between tumor and normal host tissues. Paraneoplastic hematologic syndromes are observed more rarely. Here we report a case of paraneoplastic granulocytosis in an advanced lung cancer patient.
authors.affiliation: Bégin Military Teaching Hospital, Intensive Care Unit, Saint Mandé, France.
authors.forename: Audrey
authors.initials: A
authors.lastname: Le Roy
authors.affiliation: Bégin Military Teaching Hospital, Intensive Care Unit, Saint Mandé, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Pasquier
authors.affiliation: Family Medicine Residency, David Grant Medical Center, California, USA.
authors.forename: Dillon
authors.initials: D
authors.lastname: Savard
authors.affiliation: Bégin Military Teaching Hospital, Department of biology, Saint Mandé, France.
authors.forename: Sarah
authors.initials: S
authors.lastname: Bugier
authors.affiliation: Bégin Military Teaching Hospital, Intensive Care Unit, Saint Mandé, France.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Merat
authors.affiliation: Bégin Military Teaching Hospital, Department of biology, Saint Mandé, France.
authors.forename: Jean-Etienne
authors.initials: JE
authors.lastname: Pilo
authors.affiliation: Bégin Military Teaching Hospital, Department of biology, Saint Mandé, France.
authors.forename: Hervé
authors.initials: H
authors.lastname: Delacour
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000556:secondary; D001932:Brain Neoplasms / Q000556:secondary; D002097:C-Reactive Protein / Q000032:analysis; D002289:Carcinoma, Non-Small-Cell Lung / Q000175:diagnosis* / Q000556:secondary; D017809:Fatal Outcome; D006098:Granulocytes / Q000473:pathology*; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D007964:Leukocytosis / Q000175:diagnosis*; D008175:Lung Neoplasms / Q000175:diagnosis*; D008207:Lymphatic Metastasis / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000175:diagnosis*
chemical_list: D002097:C-Reactive Protein; D007770:L-Lactate Dehydrogenase
keywords: lung neoplasms; paraneoplastic syndromes