title: [Acid-neutralizing capacity of over-the-counter gastrointestinal medications].
abstract: There is little information regarding the acid-neutralizing capacity of over-the-counter (OTC) gastrointestinal medicines. In this study, we assessed the acid-neutralizing capacity of OTC and prescribed gastrointestinal drugs based on the Japanese Pharmacopoeia 16th Edition. The acid-neutralizing capacity of the OTC drugs was calculated using experimental results for the crude materials found in the prescribed drugs based on OTC antacid quantity. The measured acid-neutralizing capacities of the OTC drugs agreed with the respective calculated values. These results indicate that the acid-neutralizing capacity of OTC drugs labeled as an antacid without information on their capacity can be estimated based on the quantity and capacity of the antacid components.
authors.affiliation: Faculty of Pharmaceutical Sciences, Setsunan University.
authors.forename: Ayano
authors.initials: A
authors.lastname: Iwazaki
authors.forename: Akihiro
authors.initials: A
authors.lastname: Tsuji
authors.forename: Kimie
authors.initials: K
authors.lastname: Imai
authors.forename: Kunio
authors.initials: K
authors.lastname: Nakanishi
mesh_terms: D000143:Acids / Q000737:chemistry*; D000863:Antacids / Q000737:chemistry*; D005765:Gastrointestinal Agents / Q000737:chemistry*; D004366:Nonprescription Drugs / Q000737:chemistry*
chemical_list: D000143:Acids; D000863:Antacids; D005765:Gastrointestinal Agents; D004366:Nonprescription Drugs