title: Total parathyroidectomy with trace amounts of parathyroid tissue autotransplantation as the treatment of choice for secondary hyperparathyroidism: a single-center experience.
abstract: BACKGROUND
  The aim of the study was to evaluate total parathyroidectomy with trace amounts of parathyroid tissue (30 mg) as a surgical option in secondary hyperparathyroidism (sHPT) treatment.
  
  
  METHODS
  From January 2008 to March 2012, 47 patients underwent parathyroidectomy. Comparisons of demographic data, symptoms, and preoperative or postoperative biochemistry were made between total parathyroidectomy with trace amounts of parathyroid tissue autotransplantation group and total parathyroidectomy group.
  
  
  RESULTS
  Out of 47 cases, 45 had successful operation. 187 parathyroid glands identified at the initial operation were reported in 47 patients. 43 patients had been diagnosed with parathyroid hyperplasia, and 4 patients had a benign adenoma. After operation, pruritus, bone pain and muscle weakness disappeared, also serum PTH and serum phosphate were declined markedly as well. After discharge, two patients (in total parathyroidectomy group) were readmitted because of postoperative hypoparathyroidism. Graft-dependent recurrence was not observed in an average follow-up of 42 months.
  
  
  CONCLUSIONS
  Total parathyroidectomy with sternocleidomastoid muscle trace amounts of parathyroid tissue autotransplantation is considered to be a feasible, safe and effective surgical option for the patients with sHPT.
authors.affiliation: Department of Thyroid and Breast Surgery, Jinan Military General Hospital of PLA, No,25 Shifan Road, Jinan 250031, People's Republic of China. heqingqing@yeah.net.
authors.forename: Qingqing
authors.initials: Q
authors.lastname: He
authors.forename: Dayong
authors.initials: D
authors.lastname: Zhuang
authors.forename: Luming
authors.initials: L
authors.lastname: Zheng
authors.forename: Ziyi
authors.initials: Z
authors.lastname: Fan
authors.forename: Peng
authors.initials: P
authors.lastname: Zhou
authors.forename: Jian
authors.initials: J
authors.lastname: Zhu
authors.forename: Songjian
authors.initials: S
authors.lastname: Duan
authors.forename: Yanning
authors.initials: Y
authors.lastname: Li
authors.forename: Yanming
authors.initials: Y
authors.lastname: Ge
authors.forename: Zhen
authors.initials: Z
authors.lastname: Lv
authors.forename: Lei
authors.initials: L
authors.lastname: Cao
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010280:Parathyroid Glands / Q000637:transplantation*; D016105:Parathyroidectomy; D012189:Retrospective Studies; D014182:Transplantation, Autologous; D016896:Treatment Outcome