title: Clinical characteristics and treatment of Herlyn-Werner-Wunderlich syndrome.
abstract: OBJECTIVE
  To investigate the clinical characteristics and treatment of the Herlyn-Werner-Wunderlich syndrome (HWWS).
  
  
  METHODS
  Sixty-one patients diagnosed with HWWS were retrospectively analyzed. HWWS is categorized into three types in China.
  
  
  RESULTS
  Age at presentation of all the cases was after menarche. The most common clinical presentations were dysmenorrhea for type I and vaginal discharge for types II and III. Clinical presentations of types II and III may not occur until reproductive age. HWWS occurred on the right in 39/61. Excision of the obstructed vaginal septum was the treatment utilized in this cohort. After surgery, subsequent pregnancies were ipsilateral in 52.9 %.
  
  
  CONCLUSIONS
  Clinical presentation in untreated HWWS suggests the anatomic anomaly. Early recognition and treatment can reduce symptoms. Pregnancies occur in both the affected and unaffected uterus.
authors.affiliation: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, 100730, China, jinhuiwang@gmail.com.
authors.forename: Jinhui
authors.initials: J
authors.lastname: Wang
authors.forename: Lan
authors.initials: L
authors.lastname: Zhu
authors.forename: Jinghe
authors.initials: J
authors.lastname: Lang
authors.forename: Zhufeng
authors.initials: Z
authors.lastname: Liu
authors.forename: Dawei
authors.initials: D
authors.lastname: Sun
authors.forename: Jinhua
authors.initials: J
authors.lastname: Leng
authors.forename: Qingbo
authors.initials: Q
authors.lastname: Fan
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis* / Q000601:surgery*; D000328:Adult; D017668:Age of Onset; D002681:China; D004412:Dysmenorrhea / Q000209:etiology; D005260:Female; D006801:Humans; D007668:Kidney / Q000002:abnormalities*; D008572:Menarche; D012189:Retrospective Studies; D013577:Syndrome; D016896:Treatment Outcome; D014599:Uterus / Q000002:abnormalities*; D014621:Vagina / Q000002:abnormalities* / Q000601:surgery*; D019522:Vaginal Discharge / Q000209:etiology