title: Preparation and characterisation of thermoresponsive nanogels for smart antibacterial fabrics.
abstract: The present investigation involves the preparation and characterisation of silver containing nanogels and their incorporation onto the surface of woven fabrics so that they can be potentially used in biomedical applications such as wound dressings. These silver nanoparticles were mixed with N-isopropylacrylamide (NIPAM) based nanogels during and at the end of polymerisation process prior to their application onto the fabrics. NIPAM based nanogels were found to have a peak of lower critical solution temperature (LCST) that is close to the human body temperature. These nanogels were applied on cotton fabrics and cured for 15 h at 30°C. Silver based nanogels were padded onto the fabrics followed by drying at 30°C overnight. Scanning electron microscopy images have shown excellent distribution of silver nanoparticles on the fabric surface. EDX analysis was also conducted to confirm the presence of silver particles on the fabric surface. The results showed that a cotton fabric treated with silver based nanogels prevented the growth of bacteria, i.e. Gram-positive (Staphylococcus epidermidis) and Gram-negative (Escherichia coli), on whereas the control cotton fabric samples exhibited considerable level of bacterial growth. Specifically, the nanogels in which the silver particles were added during the polymerisation process were observed to have higher antibacterial efficacy towards both types of bacteria.
authors.affiliation: Institute of Materials Research and Innovation, University of Bolton, UK.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Zafar
authors.affiliation: Institute of Materials Research and Innovation, University of Bolton, UK. Electronic address: t.h.shah@bolton.ac.uk.
authors.forename: Tahir
authors.initials: T
authors.lastname: Shah
authors.affiliation: Department of Textile Technology, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, India.
authors.forename: Amit
authors.initials: A
authors.lastname: Rawal
authors.affiliation: Institute of Materials Research and Innovation, University of Bolton, UK; TEI Athens, Agiou Spyrodonos, 12243 Egaleo, Athens, Greece.
authors.forename: Elias
authors.initials: E
authors.lastname: Siores
mesh_terms: D000178:Acrylamides / Q000737:chemistry; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D005782:Gels / Q000737:chemistry*; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D049329:Nanostructures / Q000737:chemistry* / Q000633:toxicity; D012834:Silver / Q000737:chemistry; D013212:Staphylococcus epidermidis / Q000187:drug effects; D013696:Temperature
chemical_list: D000178:Acrylamides; D000900:Anti-Bacterial Agents; D005782:Gels; D012834:Silver; C067295:N-isopropylacrylamide
keywords: Antibacterial; Nanogel; Nanoparticles; Polymerisation; Smart