title: Recovery of an injured corticoreticular pathway via transcallosal fibers in a patient with intracerebral hemorrhage.
abstract: BACKGROUND
  Several studies have reported on injury of the corticoreticular pathway (CRP), however, little is known about the mechanism for recovery of an injured CRP. We report on a patient with intracerebral hemorrhage (ICH) who showed recovery of an injured CRP via transcallosal fibers, which was demonstrated by diffusion tensor tractography (DTT).
  
  
  METHODS
  A 67-year-old man presented with complete paralysis (Medical Research Council: 0/5) of the left extremities at the onset of a right putaminal hemorrhage. At six weeks after onset, he presented with more severe weakness of proximal joint muscles than distal joint muscles (right shoulder abductor; 2-, finger extensor; 3+, hip flexor; 2+, ankle dorsiflexor; 3). Although his right hemiplegia had recovered well, he consistently showed more severe proximal weakness (right shoulder abductor; 3, finger extensor; 4, hip flexor; 3+, ankle dorsiflexor; 4) until 16 weeks after onset. On both six- and 16-week DTTs, in the left (affected) hemisphere, the CRP showed severe narrowing with discontinuation of the anterior fibers at the corona radiata on six-week DTT, however, the discontinued anterior fibers of the CRP were connected to the right cerebral cortex via transcallosal fibers on 16-week DTT.
  
  
  CONCLUSIONS
  We demonstrated recovery of an injured CRP via transcallosal fibers in a patient with ICH. We believe that this might be a mechanism for recovery of an injured CRP.
authors.forename: Sung Ho
authors.initials: SH
authors.lastname: Jang
authors.affiliation: Department of Physical Therapy, College of Health Sciences, Dankook University, 119, Dandae-ro, Dongnam-gu, Cheonan-si, Chungnam 330-714, Republic of Korea. eangbul@hanmail.net.
authors.forename: Sang Seok
authors.initials: SS
authors.lastname: Yeo
mesh_terms: D000368:Aged; D002540:Cerebral Cortex / Q000293:injuries* / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000473:pathology* / Q000628:therapy; D003337:Corpus Callosum / Q000293:injuries* / Q000473:pathology; D056324:Diffusion Tensor Imaging; D006801:Humans; D008297:Male; D009412:Nerve Fibers / Q000473:pathology; D009434:Neural Pathways / Q000293:injuries* / Q000473:pathology; D020127:Recovery of Function; D012154:Reticular Formation / Q000293:injuries* / Q000473:pathology; D050781:Transcranial Magnetic Stimulation; D016896:Treatment Outcome