title: Characteristics desired in clinical data warehouse for biomedical research.
abstract: OBJECTIVE
  Due to the unique characteristics of clinical data, clinical data warehouses (CDWs) have not been successful so far. Specifically, the use of CDWs for biomedical research has been relatively unsuccessful thus far. The characteristics necessary for the successful implementation and operation of a CDW for biomedical research have not clearly defined yet.
  
  
  METHODS
  THREE EXAMPLES OF CDWS WERE REVIEWED: a multipurpose CDW in a hospital, a CDW for independent multi-institutional research, and a CDW for research use in an institution. After reviewing the three CDW examples, we propose some key characteristics needed in a CDW for biomedical research.
  
  
  RESULTS
  A CDW for research should include an honest broker system and an Institutional Review Board approval interface to comply with governmental regulations. It should also include a simple query interface, an anonymized data review tool, and a data extraction tool. Also, it should be a biomedical research platform for data repository use as well as data analysis.
  
  
  CONCLUSIONS
  The proposed characteristics desired in a CDW may have limited transfer value to organizations in other countries. However, these analysis results are still valid in Korea, and we have developed clinical research data warehouse based on these desiderata.
authors.affiliation: Department of Biomedical Informatics, Asan Medical Center, Seoul, Korea.
authors.forename: Soo-Yong
authors.initials: SY
authors.lastname: Shin
authors.affiliation: Department of Biomedical Informatics, Asan Medical Center, Seoul, Korea. ; Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Woo Sung
authors.initials: WS
authors.lastname: Kim
authors.affiliation: Department of Biomedical Informatics, Asan Medical Center, Seoul, Korea. ; Department of Emergency Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. ; Division of General Internal Medicine, Brigham and Women's Hospital, Boston, MA, USA.
authors.forename: Jae-Ho
authors.initials: JH
authors.lastname: Lee
keywords: Biomedical Research; Information Storage and Retrieval; Privacy; Research Design; Research Ethics