title: Clinicopathologic factors influencing the accuracy of EUS for superficial esophageal carcinoma.
abstract: OBJECTIVE
  To identify clinicopathologic factors influencing the accuracy of a high-frequency catheter probe endoscopic ultrasonography (EUS) for superficial esophageal carcinomas (SECs).
  
  
  METHODS
  A total of 126 patients with endoscopically suspected SEC, who underwent EUS and curative treatment at Pusan National University Hospital during 2005-2013, were enrolled. We reviewed the medical records of the 126 patients and compared EUS findings with histopathologic results according to clinicopathologic factors.
  
  
  RESULTS
  A total of 114 lesions in 113 patients were included in the final analysis. The EUS assessment of tumor invasion depth was accurate in 78.9% (90/114) patients. Accuracy did not differ according to histologic type, tumor differentiation, tumor location, or macroscopic shape. However, accuracy significantly decreased for tumors ≥ 3 cm in size (P = 0.002). Overestimation and underestimation of the invasion depth occurred for 11 (9.6%) and 13 lesions (11.4%), respectively. In multivariate analyses, tumor size ≥ 3 cm was the only factor significantly associated with EUS accuracy (P = 0.031), and was specifically associated with the underestimation of invasion depth.
  
  
  CONCLUSIONS
  EUS using a high-frequency catheter probe generally provides highly accurate assessments of SEC invasion depth, but its accuracy decreases for tumors ≥ 3 cm.
authors.affiliation: Jung Im Jung, Gwang Ha Kim, Tae Kyun Kim, Young Hwa Cho, Yong Wan Sung, Mun Ki Choi, Bong Eun Lee, Geun Am Song, Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, South Korea.
authors.forename: Jung Im
authors.initials: JI
authors.lastname: Jung
authors.affiliation: Jung Im Jung, Gwang Ha Kim, Tae Kyun Kim, Young Hwa Cho, Yong Wan Sung, Mun Ki Choi, Bong Eun Lee, Geun Am Song, Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, South Korea.
authors.forename: Gwang Ha
authors.initials: GH
authors.lastname: Kim
authors.affiliation: Jung Im Jung, Gwang Ha Kim, Tae Kyun Kim, Young Hwa Cho, Yong Wan Sung, Mun Ki Choi, Bong Eun Lee, Geun Am Song, Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, South Korea.
authors.forename: Hoseok
authors.initials: H
authors.lastname: I
authors.affiliation: Jung Im Jung, Gwang Ha Kim, Tae Kyun Kim, Young Hwa Cho, Yong Wan Sung, Mun Ki Choi, Bong Eun Lee, Geun Am Song, Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, South Korea.
authors.forename: Do Youn
authors.initials: DY
authors.lastname: Park
authors.affiliation: Jung Im Jung, Gwang Ha Kim, Tae Kyun Kim, Young Hwa Cho, Yong Wan Sung, Mun Ki Choi, Bong Eun Lee, Geun Am Song, Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, South Korea.
authors.forename: Tae Kyun
authors.initials: TK
authors.lastname: Kim
authors.affiliation: Jung Im Jung, Gwang Ha Kim, Tae Kyun Kim, Young Hwa Cho, Yong Wan Sung, Mun Ki Choi, Bong Eun Lee, Geun Am Song, Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, South Korea.
authors.forename: Young Hwa
authors.initials: YH
authors.lastname: Cho
authors.affiliation: Jung Im Jung, Gwang Ha Kim, Tae Kyun Kim, Young Hwa Cho, Yong Wan Sung, Mun Ki Choi, Bong Eun Lee, Geun Am Song, Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, South Korea.
authors.forename: Yong Wan
authors.initials: YW
authors.lastname: Sung
authors.affiliation: Jung Im Jung, Gwang Ha Kim, Tae Kyun Kim, Young Hwa Cho, Yong Wan Sung, Mun Ki Choi, Bong Eun Lee, Geun Am Song, Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, South Korea.
authors.forename: Mun Ki
authors.initials: MK
authors.lastname: Choi
authors.affiliation: Jung Im Jung, Gwang Ha Kim, Tae Kyun Kim, Young Hwa Cho, Yong Wan Sung, Mun Ki Choi, Bong Eun Lee, Geun Am Song, Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, South Korea.
authors.forename: Bong Eun
authors.initials: BE
authors.lastname: Lee
authors.affiliation: Jung Im Jung, Gwang Ha Kim, Tae Kyun Kim, Young Hwa Cho, Yong Wan Sung, Mun Ki Choi, Bong Eun Lee, Geun Am Song, Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, South Korea.
authors.forename: Geun Am
authors.initials: GA
authors.lastname: Song
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D002404:Catheterization; D004724:Endoscopy; D019160:Endosonography; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D015999:Multivariate Analysis; D009361:Neoplasm Invasiveness; D015203:Reproducibility of Results; D056910:Republic of Korea; D012189:Retrospective Studies
keywords: Accuracy; Endoscopic ultrasonography; Esophageal cancer