title: Intraoperative assessment of margins in breast conservative surgery--still in use?
abstract: A positive margin in breast conserving surgery is associated with an increased risk of local recurrence. Failure to achieve clear margins results in re-excision procedures. Methods for intraoperative assessment of margins have been developed, such as frozen section analysis, touch preparation cytology, near-infrared fluorescence optical imaging, x-ray diffraction technology, high-frequency ultrasound, micro-CT, and radiofrequency spectroscopy. In this article, options that might become the method of choice in the future are discussed.
authors.affiliation: Department of Gynecology and Obstetrics, Breast Center, AGAPLESION Markus Hospital, Frankfurt am Main, Germany.
authors.forename: Marc
authors.initials: M
authors.lastname: Thill
authors.forename: Kristin
authors.initials: K
authors.lastname: Baumann
authors.forename: Jana
authors.initials: J
authors.lastname: Barinoff
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D015412:Mastectomy, Segmental; D018365:Neoplasm, Residual / Q000175:diagnosis*
keywords: breast cancer; breast conserving surgery; ductal carcinoma in situ; intraoperative margin assessment; optical imaging