title: Alkaloids from Xylariaceae sp., a marine-derived fungus.
abstract: A new pyridine derivative, 5-(2'-hydroxypropyl)pyridin-3-ol (1), with seven known alkaloids, 3-hydroxy-5-methyl-5,6-dihydro-7H-cyclopenta[b]pyridin-7-one (2), penicillenol A1 (3), penicillenol A2 (4), a mixture of quinolactacin AI (5a) and quinolactacin A2 (5b), and a mixture of quinolactacin C1 (6a) and quinolactacin C2 (6b), were isolated from the culture broth of a marine-derived fungus Xylariaceae sp. SCSGAF0086. Their structures were elucidated by spectroscopic methods. Compound 2 showed weak antimicrobial activity against Bacillus subtilis, and a mixture of 6a and 6b exhibited strong antifouling activity toward Bugula neritina larval settlement.
authors.forename: Xu-Hua
authors.initials: XH
authors.lastname: Nong
authors.forename: Xiao-Yong
authors.initials: XY
authors.lastname: Zhang
authors.forename: Xin-Ya
authors.initials: XY
authors.lastname: Xu
authors.forename: Yun-Lin
authors.initials: YL
authors.lastname: Sun
authors.forename: Shu-Hua
authors.initials: SH
authors.lastname: Qi
mesh_terms: D000470:Alkaloids / Q000737:chemistry*; D001203:Ascomycota / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D000470:Alkaloids