title: Methylene blue unresponsive methemoglobinemia.
abstract: Acquired methemoglobinemia is an uncommon blood disorder induced by exposure to certain oxidizing agents and drugs. Although parents may not give any history of toxin ingestion; with the aid of pulse-oximetry and blood gas analysis, we can diagnose methemoglobinemia. Prompt recognition of this condition is required in emergency situations to institute early methylene blue therapy. We report an unusual case of severe toxic methemoglobinemia, which did not respond to methylene blue, but was successfully managed with exchange transfusion.
authors.affiliation: Department of Pediatrics, Pediatric Intensive Care Unit, Christian Medical College, Vellore, Tamil Nadu, India.
authors.forename: Sibabratta
authors.initials: S
authors.lastname: Patnaik
authors.affiliation: Department of Pediatrics, Pediatric Intensive Care Unit, Christian Medical College, Vellore, Tamil Nadu, India.
authors.forename: Manivachagan Muthappa
authors.initials: MM
authors.lastname: Natarajan
authors.affiliation: Department of Pediatrics, Pediatric Intensive Care Unit, Christian Medical College, Vellore, Tamil Nadu, India.
authors.forename: Ebor Jacob
authors.initials: EJ
authors.lastname: James
authors.affiliation: Department of Pediatrics, Pediatric Intensive Care Unit, Christian Medical College, Vellore, Tamil Nadu, India.
authors.forename: Kala
authors.initials: K
authors.lastname: Ebenezer
keywords: Co-oximetry; exchange transfusion; methemoglobinemia; methylene blue