title: Deactivation of cationic Cu(I) and Au(I) catalysts for A(3) coupling by CH(2)C(l2) : mechanistic implications of the formation of neutral Cu(I) and Au(I) chlorides.
abstract: Care should be exercised when using CH2 Cl2 as a solvent for reactions in which amines are a reagent, since undesirable deactivation of cationic copper(I) and gold(I) catalysts to form the corresponding inactive neutral chloride complexes [LMCl] (M=Cu or Au) can occur as a result of the generation of hydrogen chloride in the medium. Cu(I) and Au(I) deactivation has been proved for the Mannich three-component coupling reaction. A series of Cu(I) and Au(I) complexes with potential mechanistic implications were isolated and characterized by X-ray crystallography.
authors.affiliation: Instituto Universitario de Tecnología Química CSIC-UPV, Universidad Politécnica de Valencia, Av. de los Naranjos s/n, 46022 Valencia (Spain).
authors.forename: Abdessamad
authors.initials: A
authors.lastname: Grirrane
authors.forename: Eleuterio
authors.initials: E
authors.lastname: Alvarez
authors.forename: Hermenegildo
authors.initials: H
authors.lastname: García
authors.forename: Avelino
authors.initials: A
authors.lastname: Corma
keywords: coordination chemistry; copper intermediates; gold intermediates; homogeneous catalysis; propargylamines