title: Effect of Fe nanoparticle on growth and glycolipid biosurfactant production under solid state culture by marine Nocardiopsis sp. MSA13A.
abstract: BACKGROUND
  Iron is an essential element in several pathways of microbial metabolism, and therefore low iron toxicity is expected on the usage of Fe nanoparticles (NPs). This study aims to determine the effect of Fe NPs on biosurfactant production by marine actinobacterium Nocardiopsis sp. MSA13A under solid state culture. Foam method was used in the production of Fe NPs which were long and fiber shaped in nature.
  
  
  RESULTS
  The SEM observation showed non toxic nature of Fe NPs as no change in the morphology of the filamentous structure of Nocardiopsis MSA13A. The production of biosurfactant by Nocardiopsis MSA13A under solid state culture supplemented with Fe NPs increased to 80% over control. The biosurfactant produced by Nocardiopsis MSA13A was characterized as glycolipid derivative which effectively disrupted the pre-formed biofilm of Vibrio pathogen.
  
  
  CONCLUSIONS
  The use of metal NPs as supplement would reduce the impact of non-metallic ions of the metal salts in a fermentation process. This would ultimately useful to achieve greener production process for biosurfactants. The present results are first report on the optimization of biosurfactant production under SSC using Fe NPs.
authors.affiliation: Department of Food Science and Technology, Pondicherry University, Puducherry 605014, India. seghalkiran@gmail.com.
authors.forename: George Seghal
authors.initials: GS
authors.lastname: Kiran
authors.forename: Lipton Anuj
authors.initials: LA
authors.lastname: Nishanth
authors.forename: Sethu
authors.initials: S
authors.lastname: Priyadharshini
authors.forename: Kumar
authors.initials: K
authors.lastname: Anitha
authors.forename: Joseph
authors.initials: J
authors.lastname: Selvin
mesh_terms: D039903:Actinobacteria / Q000254:growth & development / Q000302:isolation & purification / Q000378:metabolism*; D018441:Biofilms / Q000187:drug effects; D006017:Glycolipids / Q000096:biosynthesis* / Q000737:chemistry / Q000494:pharmacology; D007501:Iron / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D013501:Surface-Active Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D014733:Vibrio / Q000502:physiology
chemical_list: D006017:Glycolipids; D013501:Surface-Active Agents; D007501:Iron