title: Effect of implant design and bioactive glass coating on biomechanical properties of fiber-reinforced composite implants.
abstract: This study aimed to evaluate the influence of implant design and bioactive glass (BAG) coating on the response of bone to fiber-reinforced composite (FRC) implants. Three different FRC implant types were manufactured for the study: non-threaded implants with a BAG coating; threaded implants with a BAG coating; and threaded implants with a grit-blasted surface. Thirty-six implants (six implants for each group per time point) were installed in the tibiae of six pigs. After an implantation period of 4 and 12 wk, the implants were retrieved and prepared for micro-computed tomography (micro-CT), push-out testing, and scanning electron microscopy analysis. Micro-CT demonstrated that the screw-threads and implant structure remained undamaged during the installation. The threaded FRC/BAG implants had the highest bone volume after 12 wk of implantation. The push-out strengths of the threaded FRC/BAG implants after 4 and 12 wk (463°N and 676°N, respectively) were significantly higher than those of the threaded FRC implants (416°N and 549°N, respectively) and the nonthreaded FRC/BAG implants (219°N and 430°N, respectively). Statistically significant correlation was found between bone volume and push-out strength values. This study showed that osseointegrated FRC implants can withstand the static loading up to failure without fracture, and that the addition of BAG significantly improves the push-out strength of FRC implants.
authors.affiliation: Department of Oral Health Sciences, University of British Columbia Faculty of Dentistry, Vancouver, BC, Canada; Dental Implant and Osseointegration Research Chair, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
authors.forename: Ahmed M
authors.initials: AM
authors.lastname: Ballo
authors.forename: Eralp
authors.initials: E
authors.lastname: Akca
authors.forename: Tuncer
authors.initials: T
authors.lastname: Ozen
authors.forename: Niko
authors.initials: N
authors.lastname: Moritz
authors.forename: Lippo
authors.initials: L
authors.lastname: Lassila
authors.forename: Pekka
authors.initials: P
authors.lastname: Vallittu
authors.forename: Timo
authors.initials: T
authors.lastname: Närhi
mesh_terms: D000537:Aluminum Oxide / Q000737:chemistry; D000818:Animals; D001696:Biomechanical Phenomena; D015519:Bone Density / Q000502:physiology; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D003188:Composite Resins / Q000737:chemistry*; D045662:Dental Etching / Q000379:methods; D015921:Dental Implants; D003764:Dental Materials / Q000737:chemistry*; D017267:Dental Prosthesis Design; D005260:Female; D005898:Glass / Q000737:chemistry*; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D016348:Osseointegration / Q000502:physiology; D058105:Polymerization; D019904:Polymethyl Methacrylate / Q000737:chemistry; D013314:Stress, Mechanical; D013499:Surface Properties; D013552:Swine; D013977:Tibia / Q000648:ultrastructure; D013997:Time Factors; D055114:X-Ray Microtomography / Q000379:methods
chemical_list: D020099:Coated Materials, Biocompatible; D003188:Composite Resins; D015921:Dental Implants; D003764:Dental Materials; C485628:Stick resin; C403922:bioactive glass S53P4; C009753:fiberglass; D019904:Polymethyl Methacrylate; D000537:Aluminum Oxide
keywords: bioactive glass; biomechanics; dental implant; fiber-reinforced composite; osseointegration