title: Surgical management of melanoma.
abstract: Surgery remains the mainstay of treatment of every patient in whom complete excision of all disease is feasible. For clinically localized melanoma (clinical stages 0-II), wide excision and, when appropriate, sentinel lymph node biopsy are well established. The management of stage III melanoma is more contentious. Resection remains the first choice of therapy for patients with oligometastatic melanoma in accessible locations, but careful consideration of preoperative use of highly active drugs is appropriate. Decisions regarding surgical management of stage IV melanoma should routinely be made in the context of a multidisciplinary team approach.
authors.affiliation: Department of Cutaneous Oncology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA; Department of Oncologic Sciences, University of South Florida Morsani College of Medicine, Tampa, FL, USA; Department of Surgery, University of South Florida Morsani College of Medicine, Tampa, FL, USA. Electronic address: vernon.sondak@moffitt.org.
authors.forename: Vernon K
authors.initials: VK
authors.lastname: Sondak
authors.affiliation: Department of Cutaneous Oncology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA; Department of Oncologic Sciences, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
authors.forename: Geoffrey T
authors.initials: GT
authors.lastname: Gibney
mesh_terms: D018572:Disease-Free Survival; D006801:Humans; D008545:Melanoma / Q000473:pathology / Q000601:surgery*; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D011379:Prognosis; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome
keywords: Lymphadenectomy; Melanoma; Metastasectomy; Sentinel node biopsy; Surgery