title: Downregulation of neuregulin 1-ErbB4 signaling and antidepressant properties of ketamine: ErbB4 expressing pyramidal neurons may play a role.
abstract: We comment on a recent paper of Wang et al. (J Mol Neurosci, 2014), who have shown that ketamine reduces neuregulin1-ErbB4 signaling in interneurons.
authors.affiliation: Department of Psychiatry, Faculty of Medicine, Otto-von-Guericke University, Leipziger Str. 44, 39120, Magdeburg, Germany, Hans-Gert.Bernstein@med.ovgu.de.
authors.forename: Hans-Gert
authors.initials: HG
authors.lastname: Bernstein
authors.forename: Gerburg
authors.initials: G
authors.lastname: Keilhoff
authors.forename: Johann
authors.initials: J
authors.lastname: Steiner
authors.forename: Gregor
authors.initials: G
authors.lastname: Laube
authors.forename: Bernhard
authors.initials: B
authors.lastname: Bogerts
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001921:Brain / Q000378:metabolism*; D003863:Depression / Q000378:metabolism*; D007395:Interneurons / Q000378:metabolism*; D007649:Ketamine / Q000494:pharmacology*; D008297:Male; D020890:Neuregulin-1 / Q000378:metabolism*; D066247:Receptor, ErbB-4 / Q000378:metabolism*
chemical_list: D000928:Antidepressive Agents; D020890:Neuregulin-1; D007649:Ketamine; D066247:Receptor, ErbB-4