title: Inactivation performance and mechanism of Escherichia coli in aqueous system exposed to iron oxide loaded graphene nanocomposites.
abstract: The challenge to achieve efficient disinfection and microbial control without harmful disinfection byproducts calls for developing new technologies. Magnetic-graphene oxide (M-GO) with magnetic iron oxide nanoparticles well dispersed on graphene oxide (GO) nanosheets exerted excellent antibacterial activity against Escherichia coli. The antibacterial performance of M-GO was dependent on the concentration and the component mass ratio of M/GO. The synergetic antibacterial effect of M-GO was observed with M/GO mass ratio of 9.09. TEM images illustrated the interaction between E. coli cells and M-GO nanocomposites. M-GO nanomaterials were possible to deposit on or penetrate into cells leading to leakage of intercellular contents and loss of cell integrity. The inactivation mechanism of E. coli by M-GO was supposed to result from both the membrane stress and oxidation stress during the incubation period. M-GO with excellent antibacterial efficiency against E. coli and separation-convenient property from water could be potent bactericidal nanomaterials for water disinfection.
authors.affiliation: College of Environmental Science and Engineering, Hunan University, Changsha 410082, PR China; Key Laboratory of Environmental Biology and Pollution Control, Ministry of Education, Hunan University, Changsha 410082, PR China.
authors.forename: Can-Hui
authors.initials: CH
authors.lastname: Deng
authors.affiliation: College of Environmental Science and Engineering, Hunan University, Changsha 410082, PR China; Key Laboratory of Environmental Biology and Pollution Control, Ministry of Education, Hunan University, Changsha 410082, PR China. Electronic address: jilaigong@gmail.com.
authors.forename: Ji-Lai
authors.initials: JL
authors.lastname: Gong
authors.affiliation: College of Environmental Science and Engineering, Hunan University, Changsha 410082, PR China; Key Laboratory of Environmental Biology and Pollution Control, Ministry of Education, Hunan University, Changsha 410082, PR China.
authors.forename: Guang-Ming
authors.initials: GM
authors.lastname: Zeng
authors.affiliation: College of Environmental Science and Engineering, Hunan University, Changsha 410082, PR China; Key Laboratory of Environmental Biology and Pollution Control, Ministry of Education, Hunan University, Changsha 410082, PR China.
authors.forename: Cheng-Gang
authors.initials: CG
authors.lastname: Niu
authors.affiliation: College of Environmental Science and Engineering, Hunan University, Changsha 410082, PR China; Key Laboratory of Environmental Biology and Pollution Control, Ministry of Education, Hunan University, Changsha 410082, PR China.
authors.forename: Qiu-Ya
authors.initials: QY
authors.lastname: Niu
authors.affiliation: College of Environmental Science and Engineering, Hunan University, Changsha 410082, PR China; Key Laboratory of Environmental Biology and Pollution Control, Ministry of Education, Hunan University, Changsha 410082, PR China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.affiliation: College of Environmental Science and Engineering, Hunan University, Changsha 410082, PR China; Key Laboratory of Environmental Biology and Pollution Control, Ministry of Education, Hunan University, Changsha 410082, PR China.
authors.forename: Hong-Yu
authors.initials: HY
authors.lastname: Liu
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects* / Q000378:metabolism; D005290:Ferric Compounds / Q000737:chemistry / Q000494:pharmacology*; D006108:Graphite / Q000737:chemistry / Q000494:pharmacology*; D046529:Microscopy, Electron, Transmission; D053761:Nanocomposites; D013059:Spectrum Analysis, Raman; D014871:Water Microbiology
chemical_list: D000900:Anti-Bacterial Agents; D005290:Ferric Compounds; C000499:ferric oxide; D006108:Graphite
keywords: Antibacterial; Graphene oxide; Magnetic iron oxide; Oxidative stress; Water disinfection