title: Live-cell SERS endoscopy using plasmonic nanowire waveguides.
abstract: Live-cell surface-enhanced Raman spectroscopy (SERS) endoscopy is developed by using plasmonic nanowire waveguides as endoscopic probes. It is demonstrated that the probe insertion does not stress the cell. Opposed to conventional SERS endoscopy, with excitation at the hotspot within the cell, the remote excitation method yields low-background SERS spectra from specific cell compartments with minimal associated photodamage.
authors.affiliation: KU Leuven, Departement Chemie, Celestijnenlaan 200G-F, B-3001, Heverlee, Belgium.
authors.forename: Gang
authors.initials: G
authors.lastname: Lu
authors.forename: Herlinde
authors.initials: H
authors.lastname: De Keersmaecker
authors.forename: Liang
authors.initials: L
authors.lastname: Su
authors.forename: Bart
authors.initials: B
authors.lastname: Kenens
authors.forename: Susana
authors.initials: S
authors.lastname: Rocha
authors.forename: Eduard
authors.initials: E
authors.lastname: Fron
authors.forename: Chang
authors.initials: C
authors.lastname: Chen
authors.forename: Pol
authors.initials: P
authors.lastname: Van Dorpe
authors.forename: Hideaki
authors.initials: H
authors.lastname: Mizuno
authors.forename: Johan
authors.initials: J
authors.lastname: Hofkens
authors.forename: James A
authors.initials: JA
authors.lastname: Hutchison
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Uji-i
mesh_terms: D019723:Endoscopes; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006367:HeLa Cells; D006801:Humans; D008904:Miniaturization; D036103:Nanotechnology / Q000295:instrumentation*; D053770:Nanowires / Q000737:chemistry* / Q000648:ultrastructure; D012834:Silver / Q000737:chemistry*; D013347:Subcellular Fractions / Q000648:ultrastructure*; D020349:Surface Plasmon Resonance / Q000295:instrumentation*
chemical_list: D012834:Silver
keywords: remote excitation; silver nanowires; single-cell endoscopy; tip-enhanced Raman scattering