title: Femtosecond laser versus manual clear corneal incision in cataract surgery.
abstract: OBJECTIVE
  To compare functional and morphological outcomes of femtosecond laser clear corneal incision (CCI) versus manual CCI during cataract surgery.
  
  
  METHODS
  Sixty eyes of 60 patients who underwent CCI during cataract surgery were randomized into two groups: femtosecond laser CCI (30 eyes) and manual CCI (30 eyes).
  
  
  RESULTS
  There were no significant between-group differences in uncorrected distance visual acuity, corrected distance visual acuity, surgically induced astigmatism, and corneal aberrations. Keratometric astigmatism was significantly lower in the femtosecond laser CCI group compared to the manual CCI group at 30 and 180 days (P < .05). Central endothelial cell count was significantly higher in the femtosecond laser CCI group compared to the manual CCI group at 7 and 30 days postoperatively (P < .05). A lower increase of corneal thickness at the incision site was observed at 30 and 180 days postoperatively in the femtosecond laser CCI group compared to the manual CCI group (P < .05). In addition, femtosecond laser CCI showed a better morphology (lower percentage of endothelial and epithelial gaping and endothelial misalignment) compared to manual CCI at different time points. Total phacoemulsification time was significantly lower in the femtosecond laser CCI group (P < .05).
  
  
  CONCLUSIONS
  The femtosecond laser procedure was safe, efficient, and less damaging, as evidenced by lower central endothelial cell loss, lower increase of corneal thickness at the incision site, and better tunnel morphology compared to the manual technique.
authors.forename: Leonardo
authors.initials: L
authors.lastname: Mastropasqua
authors.forename: Lisa
authors.initials: L
authors.lastname: Toto
authors.forename: Alessandra
authors.initials: A
authors.lastname: Mastropasqua
authors.forename: Luca
authors.initials: L
authors.lastname: Vecchiarino
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Mastropasqua
authors.forename: Emilio
authors.initials: E
authors.lastname: Pedrotti
authors.forename: Marta
authors.initials: M
authors.lastname: Di Nicola
mesh_terms: D000368:Aged; D001251:Astigmatism / Q000503:physiopathology; D019923:Capsulorhexis / Q000379:methods; D002386:Cataract / Q000503:physiopathology; D002452:Cell Count; D003315:Cornea / Q000601:surgery*; D057108:Corneal Wavefront Aberration / Q000503:physiopathology; D004728:Endothelium, Corneal / Q000473:pathology; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D019654:Lens Implantation, Intraocular; D008297:Male; D018918:Phacoemulsification / Q000379:methods*; D011446:Prospective Studies; D014792:Visual Acuity / Q000502:physiology