title: A latent reaction in a model GFP chromophore revealed upon confinement: photohydroxylation of ortho-halo benzylidene-3-methylimidazolidiones via an electrocylization process.
abstract: Excited state behavior of halogen substituted model GFP chromophores was investigated in an acetonitrile solution and in a confined environment provided by an octa acid capsule in water. Of the ortho, meta, and para halogen substituted GFP chromophores only the ortho compounds gave a new product resulting from an unprecedented photosubstitution of halogens by the hydroxyl group. This unusual reaction highlights the importance of confined spaces in bringing about some unattainable photoreactions.
authors.affiliation: Department of Chemistry, University of Miami , Coral Gables, Florida 33146, United States.
authors.forename: Shampa R
authors.initials: SR
authors.lastname: Samanta
authors.forename: José P
authors.initials: JP
authors.lastname: Da Silva
authors.forename: Anthony
authors.initials: A
authors.lastname: Baldridge
authors.forename: Laren M
authors.initials: LM
authors.lastname: Tolbert
authors.forename: V
authors.initials: V
authors.lastname: Ramamurthy