title: Scedosporium prolificans osteomyelitis following penetrating injury: A case report.
abstract: Scedosporium prolificans are opportunistic moulds that can cause mycetoma following penetrating injuries. This fungus is more virulent than other species and treatment options are limited. Here we describe the first known case in the UK of S. prolificans osteomyelitis, in a 4 year old following penetrating injury. Successful outcome with limb salvage and foot function is achieved after repeated surgical debridement, and combination chemotherapy with voriconazole/terbinafine.
authors.affiliation: Department of Microbiology, University Hospital of Wales, Cardiff, United Kingdom.
authors.forename: S
authors.initials: S
authors.lastname: Bhagavatula
authors.affiliation: Department of Microbiology, University Hospital of Wales, Cardiff, United Kingdom.
authors.forename: L
authors.initials: L
authors.lastname: Vale
authors.affiliation: Department of Paediatrics and Child Health, University Hospital of Wales, Cardiff, United Kingdom.
authors.forename: J
authors.initials: J
authors.lastname: Evans
authors.affiliation: Department of Paediatric Orthopedics, University Hospital of Wales, Cardiff, United Kingdom.
authors.forename: C
authors.initials: C
authors.lastname: Carpenter
authors.affiliation: Department of Microbiology, University Hospital of Wales, Cardiff, United Kingdom.
authors.forename: R A
authors.initials: RA
authors.lastname: Barnes
keywords: Fungal osteomyelitis; Mycetoma; Scedosporium prolificans; Terbinafine; Voriconazole