title: Decreased levels of serum nesfatin-1 in patients with preeclampsia.
abstract: BACKGROUND
  Nesfatin-1 is implicated to possess an anti-inflammatory effect.
  
  
  OBJECTIVE
  The aim of our study is to investigate whether abnormal serum levels of nesfatin-1 are associated with the presence and severity of preeclampsia.
  
  
  METHODS
  A total of 120 women with preeclampsia and 92 women with uncomplicated pregnancies were enrolled in this study.
  
  
  RESULTS
  Women with preeclampsia showed significantly reduced levels of serum nesfatin-1 levels than women with uncomplicated pregnancies. Serum nesfatin-1 levels were significantly decreased in women with severe preeclampsia compared with women with mild preeclampsia.
  
  
  CONCLUSIONS
  Decreased serum nesfatin-1 levels are associated with the presence and severity of preeclampsia.
authors.affiliation: The Second Department of Obstetrics and.
authors.forename: Cuijuan
authors.initials: C
authors.lastname: Zhang
authors.forename: Ying
authors.initials: Y
authors.lastname: Wang
authors.forename: Yunhai
authors.initials: Y
authors.lastname: Wang
authors.forename: Jie
authors.initials: J
authors.lastname: Li
authors.forename: Ruxin
authors.initials: R
authors.lastname: Liu
authors.forename: Hong
authors.initials: H
authors.lastname: Liu
mesh_terms: D000328:Adult; D001794:Blood Pressure; D002135:Calcium-Binding Proteins / Q000097:blood*; D004268:DNA-Binding Proteins / Q000097:blood*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007333:Insulin Resistance; D016014:Linear Models; D009419:Nerve Tissue Proteins / Q000097:blood*; D000080866:Nucleobindins; D011225:Pre-Eclampsia / Q000097:blood* / Q000175:diagnosis / Q000503:physiopathology; D011247:Pregnancy; D012720:Severity of Illness Index; D014280:Triglycerides / Q000097:blood
chemical_list: D002135:Calcium-Binding Proteins; D004268:DNA-Binding Proteins; C000630650:NUCB2 protein, human; D009419:Nerve Tissue Proteins; D000080866:Nucleobindins; D014280:Triglycerides
keywords: Inflammation; nesfatin-1; obesity; preeclampsia