title: Determination of serotonin on platinum electrode modified with carbon nanotubes/polypyrrole/silver nanoparticles nanohybrid.
abstract: A new sensor has been developed by a simple electrodeposition of multi-walled carbon nanotubes (MWCNT), polypyrrole (PPy) and colloidal silver nanoparticles on the platinum (Pt) electrode surface. The Pt/MWCNT/PPy/AgNPs electrode was applied to the detection of serotonin in plasmatic serum samples using differential pulse voltammetry (DPV). The synergistic effect of MWCNT/PPy/AgNPs nanohybrid formed yielded a LOD of 0.15 μmol L(-1) (26.4 μg L(-1)). Reproducibility and repeatability values of 2.2% and 1.7%, respectively, were obtained compared to the conventional procedure. The proposed electrode can be an effective material to be used in biological analysis.
authors.affiliation: Instituto de Química de São Carlos, Universidade de São Paulo, C.P. 780, 13560-970, São Carlos, São Paulo, Brazil. Electronic address: ivana@iqsc.usp.br.
authors.forename: Ivana
authors.initials: I
authors.lastname: Cesarino
authors.affiliation: Instituto de Química de São Carlos, Universidade de São Paulo, C.P. 780, 13560-970, São Carlos, São Paulo, Brazil.
authors.forename: Heloisa V
authors.initials: HV
authors.lastname: Galesco
authors.affiliation: Instituto de Química de São Carlos, Universidade de São Paulo, C.P. 780, 13560-970, São Carlos, São Paulo, Brazil.
authors.forename: Sergio A S
authors.initials: SA
authors.lastname: Machado
mesh_terms: D001205:Ascorbic Acid / Q000737:chemistry; D055664:Electrochemical Techniques; D004566:Electrodes; D006801:Humans; D006863:Hydrogen-Ion Concentration; D053768:Metal Nanoparticles / Q000737:chemistry; D049329:Nanostructures / Q000737:chemistry*; D037742:Nanotubes, Carbon / Q000737:chemistry; D010084:Oxidation-Reduction; D011108:Polymers / Q000737:chemistry; D011758:Pyrroles / Q000737:chemistry; D012701:Serotonin / Q000032:analysis* / Q000097:blood; D012834:Silver / Q000737:chemistry; D014527:Uric Acid / Q000737:chemistry
chemical_list: D037742:Nanotubes, Carbon; D011108:Polymers; D011758:Pyrroles; D014527:Uric Acid; C067635:polypyrrole; D012701:Serotonin; D012834:Silver; D001205:Ascorbic Acid
keywords: Carbon nanotubes; Nanohybrid; Polypyrrole; Serotonin; Silver nanoparticles