title: Histology and clinical outcome of benign and malignant vascular lesions primary to feline cervical lymph nodes.
abstract: A novel form of primary feline hemangiosarcoma and additional cases of plexiform vascularization in the cervical lymph nodes are reported. Sixteen cases of feline lymphadenopathy attributed to abnormal vascular proliferation were identified and evaluated. Most of these lesions were diagnosed histologically as hemangiosarcoma. However, lesions of plexiform vascularization, with and without areas of putative malignant transformation, were also identified. Mean age of the cats was 11 years (range, 3-16 years) with most being domestic shorthair and medium hair (13). Two domestic long hair and 1 Maine Coon were identified. Excisional nodal biopsy was performed in 15 cases and incisional biopsy in 1 case. Six cats were euthanized due to their disease. Survival times ranged from ≤ 1 month to ≥ 30 months. We provide a new clinical differential for cervical lymphadenopathy in cats that is not widely recognized. Proper identification of primary nodal vascular lesions in cats will enable further characterization of clinical features and biologic behavior to determine specific therapy.
authors.affiliation: Veterinary Specialists of North Texas, Dallas, TX, USA eroof@vsnt.com.
authors.forename: E
authors.initials: E
authors.lastname: Roof-Wages
authors.affiliation: VDxVeterinary Pathology Services, Davis, CA, USA.
authors.forename: T
authors.initials: T
authors.lastname: Spangler
authors.affiliation: Necropsy Services Group, Davis, CA, USA.
authors.forename: W L
authors.initials: WL
authors.lastname: Spangler
authors.affiliation: VCA Bay Area Veterinary Specialists, San Leandro, CA, USA.
authors.forename: C T
authors.initials: CT
authors.lastname: Siedlecki
mesh_terms: D000818:Animals; D001706:Biopsy / Q000662:veterinary; D002371:Cat Diseases / Q000473:pathology*; D002415:Cats; D005260:Female; D006394:Hemangiosarcoma / Q000473:pathology / Q000662:veterinary*; D008198:Lymph Nodes / Q000473:pathology; D000072281:Lymphadenopathy / Q000473:pathology / Q000662:veterinary*; D008297:Male; D009333:Neck / Q000473:pathology
keywords: feline; hemangiosarcoma; lymph node; plexiform vascularization