title: Facile solid phase peptide synthesis with a Re-lysine conjugate generated via a one-pot procedure.
abstract: We have synthesized a Re(CO)3-modified lysine via a one-pot Schiff base formation reaction that can be used in the solid phase peptide synthesis. To demonstrate its potential use, we have attached it to a neurotensin fragment and observed uptake into human umbilical vascular endothelial cells.
authors.affiliation: Department of Chemistry, University of Akron, Akron, OH 44325-3601, USA. ziegler@uakron.edu.
authors.forename: Kullapa
authors.initials: K
authors.lastname: Chanawanno
authors.forename: Joel
authors.initials: J
authors.lastname: Caporoso
authors.forename: Vinay
authors.initials: V
authors.lastname: Kondeti
authors.forename: Sailaja
authors.initials: S
authors.lastname: Paruchuri
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Leeper
authors.forename: Richard S
authors.initials: RS
authors.lastname: Herrick
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Ziegler
mesh_terms: D000595:Amino Acid Sequence; D042783:Endothelial Cells / Q000378:metabolism; D006801:Humans; D008239:Lysine / Q000737:chemistry*; D009496:Neurotensin / Q000737:chemistry* / Q000378:metabolism; D060327:Solid-Phase Synthesis Techniques / Q000379:methods*
chemical_list: D009496:Neurotensin; D008239:Lysine