title: Comparison of office, home, and ambulatory blood pressure in heart transplant recipients.
abstract: BACKGROUND
  The purpose of this study was to prospectively evaluate the relationship between office, home, and ambulatory blood pressure (BP) in heart transplant recipients.
  
  
  RESULTS
  The study enrolled 30 adults ≥ 6 months after heart transplantation. Morning seated office BP was measured with the use of an automatic device at 3 outpatient visits. Seated home BP was measured in the morning and evening for 5 consecutive days. Ambulatory BP was measured over 24 hours with the use of a Spacelabs monitor. The strongest correlation was observed between home and 24-hour ambulatory BP (r = 0.79 systolic; r = 0.72 diastolic). Office and home systolic BPs were significantly lower than daytime ambulatory BP (office, -3.7 mm Hg, P = .009; home, -2.6 mm Hg, P = .05). Ambulatory monitoring identified more participants with BP above hypertensive limits than did office or home measurements (63%, 50%, and 13%, respectively; P = .003). Ambulatory monitoring also revealed high BP loads, abnormal nocturnal BP patterns (eg, 30% nondippers), and a high percentage of masked hypertension (37% home, 50% ambulatory).
  
  
  CONCLUSIONS
  Office and home BP monitoring are acceptable but may underestimate BP burden in heart transplant recipients. Additional studies are needed to determine which BP method is superior for the management of hypertension and associated outcomes after heart transplantation.
authors.affiliation: Department of Pharmaceutical Sciences, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado. Electronic address: christina.aquilante@ucdenver.edu.
authors.forename: Christina L
authors.initials: CL
authors.lastname: Aquilante
authors.affiliation: Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado.
authors.forename: Robert L
authors.initials: RL
authors.lastname: Page
authors.affiliation: Department of Pharmaceutical Sciences, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado.
authors.forename: Anh
authors.initials: A
authors.lastname: Vu
authors.affiliation: Department of Pharmaceutical Sciences, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado.
authors.forename: Nicholai
authors.initials: N
authors.lastname: Roscoe
authors.affiliation: Division of Cardiology, School of Medicine, University of Colorado, Aurora, Colorado.
authors.forename: Eugene E
authors.initials: EE
authors.lastname: Wolfel
authors.affiliation: Division of Cardiology, School of Medicine, University of Colorado, Aurora, Colorado.
authors.forename: JoAnn A
authors.initials: JA
authors.lastname: Lindenfeld
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure / Q000502:physiology*; D001795:Blood Pressure Determination / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000601:surgery*; D016027:Heart Transplantation; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D015203:Reproducibility of Results; D012648:Self Care; D013997:Time Factors; D066027:Transplant Recipients; D055815:Young Adult
keywords: Blood pressure measurement; cardiac transplantation; hypertension