title: The Clinical, Radiographic and Histological evaluation of three different concentrations of Formocresol as a pulpotomy agent.
abstract: BACKGROUND
  Formocresol, though the center of much controversy is still the most widely used medicament for primary teeth pulpotomy and an intracanal medicament which has undergone a lengthy evolution to shorten the formocresol application time and reduce the concentration of formocresol exposure to the pulp tissue. Hence, the determination of the actual effective dose and concentration of formocresol for clinical application in primary teeth is an important area of research and a thorough clinical, radiographic and histological investigation in human subjects is very much needed.
  
  
  METHODS
  The study was conducted on 45 primary molars for the Clinical, Radiographic study and 45 premolars orthodontically indicated for extraction for the Histological study. The samples were randomly and equally divided into 3 groups of 15 each for pulpotomy with full strength formocresol, 1:5 diluted formocresol and 1:25 diluted formocresol respectively. The pulpotomized primary molars were clinically evaluated at 1st, 3rd, 6th and 9th month while the pulpotomized premolars were subjected for histological evaluation after extraction.
  
  
  RESULTS
  Obtained by chi-square test revealed that all the pulpotomized primary molars were asymptomatic till the end of the study period; suggesting 100% clinical and radiographic success while histologically, the three concentrations of formocresol showed decreased severity of fixation of the pulp tissue with decreasing concentration of formocresol.
  
  
  CONCLUSIONS
  It can be inferred that the diluted formulations (1:5 and 1:25) of formocresol are equally efficient when compared to full-strength formocresol and thus, can be recommended for pulpotomy in primary teeth. How to cite the article: Goyal S, Abuwala T, Joshi K, Mehta J, Indushekar KR, Hallikerimath S. The Clinical, Radiographic and Histological evaluation of three different concentrations of Formocresol as a pulpotomy agent. J Int Oral Health 2014;6(2):118-25.
authors.affiliation: Department of Pedodontics and Preventive Dentistry, Government Dental College and Hospital, Ahmedabad, Gujarat, India.
authors.forename: Swati
authors.initials: S
authors.lastname: Goyal
authors.affiliation: Department of Conservative Dentistry and Endodontics, Government Dental College and Hospital, Ahmedabad, Gujarat, India.
authors.forename: Tasnima
authors.initials: T
authors.lastname: Abuwala
authors.affiliation: Department of Pedodontics and Preventive Dentistry, Government Dental College and Hospital, Jamnagar, Gujarat, India.
authors.forename: Keyur
authors.initials: K
authors.lastname: Joshi
authors.affiliation: Department of Conservative Dentistry and Endodontics, Government Dental College and Hospital, Jamnagar, Gujarat, India.
authors.forename: Jahnvi
authors.initials: J
authors.lastname: Mehta
authors.affiliation: Department of Pedodontics and Preventive Dentistry, Sudha Rustagi Dental College of Dental Sciences and Research, Bhopani, Faridabad, Haryana, India.
authors.forename: K R
authors.initials: KR
authors.lastname: Indushekar
authors.affiliation: Department of Oral Pathology, KLE VK Institute of Dental Sciences, Belgaum, Karnataka, India.
authors.forename: Seema
authors.initials: S
authors.lastname: Hallikerimath
keywords: Dilute formocresol; formocresol; primary teeth; pulpotomy