title: Determination of flumioxazin residue in food samples through a sensitive fluorescent sensor based on click chemistry.
abstract: A sensitive and selective fluorescent sensor for flumioxazin was designed based on the formation of strong fluorescence compound (1,2,3-triazole compounds) via the reaction of the alkynyl group in flumioxazin with 3-azido-7-hydroxycoumarin, a weak-fluorescent compound, through the Cu(+)-catalysed azide-alkyne cycloaddition (CuAAC) reaction. The fluorescence increase factor (represented by F/F0) of the system exhibited a good linear relationship with the concentrations of flumioxazin in the range of 0.25-6.0 μg/L with a detection limit of 0.18 μg/L (S/N=3). Also, the proposed fluorescent sensor demonstrated good selectivity for flumioxazin assay even in the presence of high concentration of other pesticides. Based on such high sensitivity and selectivity, the proposed fluorescent sensor has been applied to test the flumioxazin residue in some vegetable and water samples with satisfied results.
authors.affiliation: Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Fuzhou University, Fuzhou, Fujian 350002, China.
authors.forename: Lijun
authors.initials: L
authors.lastname: Lu
authors.affiliation: Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Fuzhou University, Fuzhou, Fujian 350002, China.
authors.forename: Linlin
authors.initials: L
authors.lastname: Yang
authors.affiliation: Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Fuzhou University, Fuzhou, Fujian 350002, China.
authors.forename: Huijian
authors.initials: H
authors.lastname: Cai
authors.affiliation: Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Fuzhou University, Fuzhou, Fujian 350002, China.
authors.forename: Lan
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Fuzhou University, Fuzhou, Fujian 350002, China. Electronic address: zylin@fzu.edu.cn.
authors.forename: Zhenyu
authors.initials: Z
authors.lastname: Lin
authors.affiliation: Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Fuzhou University, Fuzhou, Fujian 350002, China.
authors.forename: Longhua
authors.initials: L
authors.lastname: Guo
authors.affiliation: Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Fuzhou University, Fuzhou, Fujian 350002, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Qiu
authors.affiliation: Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Fuzhou University, Fuzhou, Fujian 350002, China.
authors.forename: Guonan
authors.initials: G
authors.lastname: Chen
mesh_terms: D001386:Azides / Q000737:chemistry*; D048588:Benzoxazines / Q000032:analysis* / Q000737:chemistry; D057930:Click Chemistry; D003374:Coumarins / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D005504:Food Analysis / Q000379:methods*; D006540:Herbicides / Q000032:analysis*; D057230:Limit of Detection; D010797:Phthalimides / Q000032:analysis* / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D014675:Vegetables / Q000737:chemistry; D014867:Water / Q000737:chemistry
chemical_list: C507184:3-azido-7-hydroxycoumarin; D001386:Azides; D048588:Benzoxazines; D003374:Coumarins; D005456:Fluorescent Dyes; D006540:Herbicides; D010797:Phthalimides; D014867:Water; C106487:flumioxazin
keywords: Click chemistry; Flumioxazin; Fluorescent; Pesticide residue