title: Acute renal failure and metformin-associated lactic acidosis following colonoscopy.
abstract: Two patients with type 2 DM developed acute kidney injury and lactic acidosis following colonoscopy despite withholding metformin. We recommend that DM patients on metformin also withhold ACEI, ARB until their dehydration is reversed after colonoscopy. This should reduce the risk of acute renal failure (ARF) and of lactic acidosis.
authors.affiliation: Liverpool Hospital Liverpool Hospital, Liverpool 2170, NSW, Australia. Electronic address: nobeen36@hotmail.com.
authors.forename: Mohammad I
authors.initials: MI
authors.lastname: Hussain
authors.affiliation: University of New South Wales Liverpool Hospital, Liverpool 2170, NSW, Australia. Electronic address: b.hall@unsw.edu.au.
authors.forename: Bruce M
authors.initials: BM
authors.lastname: Hall
authors.affiliation: Prince of Wales Hospital Barker Street, Randwick, 2031, NSW, Australia. Electronic address: Barbara.Depczynski@sesiahs.health.nsw.gov.au.
authors.forename: Barbara
authors.initials: B
authors.lastname: Depczynski
authors.affiliation: Liverpool Hospital, Locked Bag 7103, Liverpool BC 1871, NSW, Australia. Electronic address: Susan.connor2@sswahs.nsw.gov.au.
authors.forename: Susan J
authors.initials: SJ
authors.lastname: Connor
mesh_terms: D000140:Acidosis, Lactic / Q000139:chemically induced* / Q000473:pathology; D058186:Acute Kidney Injury / Q000209:etiology* / Q000473:pathology; D000368:Aged; D003113:Colonoscopy; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects*; D008297:Male; D008687:Metformin / Q000009:adverse effects*; D011379:Prognosis; D012307:Risk Factors
chemical_list: D007004:Hypoglycemic Agents; D008687:Metformin
keywords: ACEI or ARB; Acute renal failure (ARF); Colonoscopy; Lactic acidosis; Metformin