title: Parameter comparison of white matter diffusion tensor imaging (DTI) in rhesus macaques (Macaca mulatta).
abstract: In this study, we analyzed diffusion tensor imaging (DTI) results of brain white matter in rhesus macaques (Macaca mulatta) with four different parameter settings and found that the sequence A (b=1 000 s/mm(2), spatial resolution=1.25 mm×1.25 mm× 1.25 mm, numbers of direction=33, NSA=3) and B (b=800 s/mm(2), spatial resolution=1.25 mm×1.25 mm×1.25 mm, numbers of direction=33, NSA=3) could accurately track coarse fibers. The fractional anisotropy (FA) derived from sequence C (b=1 000s/mm(2), spatial resolution=0.55 mm×0.55 mm×2.5 mm, direction number=33, NSA=3) was too fuzzy to be used in tracking white matter fibers. By comparison, the high resolution and the FA with high contrast of gray matter and white matter derived from sequence D (b=800 s/mm(2), spatial resolution=1.0 mm×1.0 mm ×1.0 mm, numbers of direction=33, NSA=3) qualified in its application in tracking both thick and thin fibers, making it an optimal DTI setting for rhesus macaques.
authors.affiliation: Department of Medical Imaging, the First Affiliated Hospital of Kunming Medical University, Kunming 650032, China.
authors.forename: Yin
authors.initials: Y
authors.lastname: Mo
authors.affiliation: Department of Medical Imaging, the First Affiliated Hospital of Kunming Medical University, Kunming 650032, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Chao
authors.affiliation: National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China.
authors.forename: Ming
authors.initials: M
authors.lastname: Song
authors.affiliation: National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China.
authors.forename: Ci-Rong
authors.initials: CR
authors.lastname: Liu
authors.affiliation: Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.
authors.forename: Hui-Lang
authors.initials: HL
authors.lastname: Liu
authors.affiliation: Department of Neurology, the First Yunnan Provincial Hospital, Kunming 650032, China. yu_hualin@163.com.
authors.forename: Xi-Ying
authors.initials: XY
authors.lastname: Qian
authors.affiliation: Laboratory of Primate Neuroscience, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China. zxd-9@163.com.
authors.forename: Xu-Dong
authors.initials: XD
authors.lastname: Zhao
mesh_terms: D000818:Animals; D001921:Brain / Q000033:anatomy & histology* / Q000254:growth & development; D056324:Diffusion Tensor Imaging / Q000379:methods / Q000662:veterinary*; D008253:Macaca mulatta / Q000033:anatomy & histology* / Q000254:growth & development
keywords: DTI; Rhesus macaque; Whiter matter