title: Amantadine induced corneal edema in a patient with primary progressive freezing of gait.
abstract: Amantadine is commonly used for Parkinsonism. However amantadine can induce adverse corneal reaction. Here we report a patient with primary progressive freezing of gait who had severe corneal edema associated with amantadine, which was reversible after discontinuation of the amantadine. This report alerts neurologists for this reversible but potentially critical corneal edema in patients with Parkinsonism who are receiving amantadine.
authors.affiliation: Department of Neurology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea ; Parkinson's Disease Study Group, Seoul National University Hospital, Seoul, Korea.
authors.forename: Young Eun
authors.initials: YE
authors.lastname: Kim
authors.affiliation: Parkinson's Disease Study Group, Seoul National University Hospital, Seoul, Korea ; Department of Neurology, Ewha Womans University Mokdong Hospital, Seoul, Korea.
authors.forename: Ji Young
authors.initials: JY
authors.lastname: Yun
authors.affiliation: Parkinson's Disease Study Group, Seoul National University Hospital, Seoul, Korea ; Department of Neurology, Ulsan University Hospital, Ulsan, Korea.
authors.forename: Hui-Jun
authors.initials: HJ
authors.lastname: Yang
authors.affiliation: Parkinson's Disease Study Group, Seoul National University Hospital, Seoul, Korea ; Department of Neurology and Movement Disorder Center, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Han-Joon
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Mee Kum
authors.initials: MK
authors.lastname: Kim
authors.affiliation: Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Won Ryang
authors.initials: WR
authors.lastname: Wee
authors.affiliation: Parkinson's Disease Study Group, Seoul National University Hospital, Seoul, Korea ; Department of Neurology and Movement Disorder Center, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Beom S
authors.initials: BS
authors.lastname: Jeon
keywords: Amantadine; Corneal edema; Parkinsonism