title: Cardioprotective and antioxidant effects of oleogum resin "Olibanum" from Bos Boswellia carteri Birdw. (Bursearceae).
abstract: One of the leading causes of death worldwide is cardiovascular disease, hence searching for a cure is an important endeavor. The totally safe, edible, and inexpensive Boswellia plant exudate, known as olibanum or frankincense, is considered to possess diverse medicinal values in traditional medicine and from recent biological studies. Investigating the cardioprotective and antioxidant activities of olibanum from a Boswellia species, family Bursearaceae, namely Boswellia carteri Birdw. was the aim of this study. Cardioprotective activity was evaluated using a model of myocardial infarction induced by isoprenaline (ISO), while antioxidant activity was tested adopting nitric oxide scavenging (NOS) and azino-bis-3-ethyl benzthiazoline-6-sulfonic acid (ABTS) assays. The results revealed a mild cardioprotective effect and weak antioxidant activity.
authors.affiliation: Pharmacognosy Department, Faculty of Pharmacy, Mansoura University, 35516, Egypt. Electronic address: ahmedawadzaki@yahoo.co.uk.
authors.forename: Ahmed A
authors.initials: AA
authors.lastname: Zaki
authors.affiliation: Pharmacognosy Department, Faculty of Pharmacy, Mansoura University, 35516, Egypt.
authors.forename: Nadia E
authors.initials: NE
authors.lastname: Hashish
authors.affiliation: Pharmacognosy Department, Faculty of Pharmacy, Mansoura University, 35516, Egypt.
authors.forename: Mohamed A
authors.initials: MA
authors.lastname: Amer
authors.affiliation: Pharmacognosy Department, Faculty of Pharmacy, Mansoura University, 35516, Egypt.
authors.forename: Mohamed-Farid
authors.initials: MF
authors.lastname: Lahloub
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage* / Q000032:analysis; D029743:Boswellia / Q000737:chemistry*; D065260:Frankincense / Q000008:administration & dosage* / Q000032:analysis; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000473:pathology; D009206:Myocardium / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000975:Antioxidants; D065260:Frankincense
keywords: Antioxidant; Boswellia carteri; Cardiovascular diseases; Frankincense; Olibanum