title: Body burden of Hg in different bio-samples of mothers in Shenyang city, China.
abstract: Hg is an accumulative and neuro-toxic heavy metal which has a wide range of adverse effects in human health. However, few studies are available on body burden of Hg level in different bio-samples of pregnant women in Chinese population. Therefore, this study evaluated Hg levels in different maternal bio-samples in Shenyang city, China and investigated the correlation of Hg levels in different bio-samples. From October to December 2008, 200 pregnant women about to deliver their babies at ShengJing Hospital (Shenyang city, northeast of China) participated in this study. The geometric mean (GM) of Hg levels in cord blood, maternal venous blood, breast milk, and maternal urine were 2.18 µg/L, 1.17 µg/L, 1.14 µg/L, and 0.73 µg/L, respectively, and the GM of maternal hair Hg level was 404.45 µg/kg. There was a strong correlation between cord blood and maternal blood total Hg level (r = 0.713, P<0.001). Frequency of fish consumption more than or equal to 3 times per week during pregnancy was suggested as a significant risk factor of prenatal Hg exposure (unadjusted OR 3.5, adjusted OR 2.94, P<0.05). This study provides evidence about Hg burden of mothers and the risk factors of prenatal Hg exposure in Shenyang city, China.
authors.affiliation: MOE-Shanghai Key Lab of Children's Environmental Health, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
authors.forename: Min-Ming
authors.initials: MM
authors.lastname: Li
authors.affiliation: MOE-Shanghai Key Lab of Children's Environmental Health, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
authors.forename: Mei-Qin
authors.initials: MQ
authors.lastname: Wu
authors.affiliation: MOE-Shanghai Key Lab of Children's Environmental Health, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Xu
authors.affiliation: Department of Gynecology and Obstetrics, Shengjing Hospital Affiliated to China Medical University, Shenyang, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Du
authors.affiliation: MOE-Shanghai Key Lab of Children's Environmental Health, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
authors.forename: Chong-Huai
authors.initials: CH
authors.lastname: Yan
mesh_terms: D000328:Adult; D001822:Body Burden; D002947:Cities / Q000706:statistics & numerical data*; D004781:Environmental Exposure / Q000032:analysis; D004785:Environmental Pollutants / Q000032:analysis*; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D006798:Housing; D006801:Humans; D008628:Mercury / Q000032:analysis* / Q000097:blood / Q000652:urine; D008895:Milk, Human / Q000737:chemistry; D009035:Mothers / Q000706:statistics & numerical data*; D011247:Pregnancy; D012307:Risk Factors; D012959:Socioeconomic Factors; D055815:Young Adult
chemical_list: D004785:Environmental Pollutants; D008628:Mercury