title: Ciprofloxacin-induced crystal nephropathy.
abstract: Ciprofloxacin is a commonly used antibiotic. Renal side effects are rare and are usually immune mediated. Clinical and experimental studies have suggested that crystalluria and crystal nephropathy occur in alkaline urine. Preexisting kidney function impairment, high dose of the medication, and advanced age predispose to this complication. We report a case of crystal nephropathy in a young woman treated with ciprofloxacin and a nonsteroidal anti-inflammatory drug.
authors.affiliation: Department of Nephrology, Hedi Chaker Hospital; Renal Pathology Unit UR 12 ES 14, Faculty of Medicine, Sfax, Tunisia. KhawlaKammoun2002@yahoo.fr.
authors.forename: Khawla
authors.initials: K
authors.lastname: Kammoun
authors.forename: Faical
authors.initials: F
authors.lastname: Jarraya
authors.forename: Saloua
authors.initials: S
authors.lastname: Makni
authors.forename: Lobna
authors.initials: L
authors.lastname: Ben Mahmoud
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Kharrat
authors.forename: Mohamed
authors.initials: M
authors.lastname: Ben Hmida
authors.forename: Khaled
authors.initials: K
authors.lastname: Zeghal
authors.forename: Tahia
authors.initials: T
authors.lastname: Boudawara
authors.forename: Jamil
authors.initials: J
authors.lastname: Hachicha
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D002939:Ciprofloxacin / Q000009:adverse effects*; D003460:Crystallization; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced*; D008528:Mefenamic Acid / Q000009:adverse effects; D014552:Urinary Tract Infections / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D008528:Mefenamic Acid; D002939:Ciprofloxacin