title: Improving treatment for opioid dependence: a perspective from the Ohio Valley node of the NIDA Clinical Trials Network.
abstract: OBJECTIVE
  Rates of adoption of evidenced-based practices, including the use of medications, to treat opioid dependence are low and severely limit secondary prevention efforts to curtail the prescription drug epidemic.
  
  
  OBJECTIVE
  The goal of this article was to describe how involvement in a research clinical trials network (CTN) facilitated the adoption of medications to treat opioid dependence at two community-based treatment programs (CTPs) affiliated with the Ohio Valley Node (OVN) of the National Institute on Drug Abuse's (NIDA) CTN.
  
  
  CONCLUSIONS
  Participation in a CTN may facilitate adoption by providing the infrastructure for trialability and observability, but the most critical function may be the knowledge translation that occurs through the individual-level professional relationships that develop.
  
  
  CONCLUSIONS
  Community-based treatment providers' involvement in research networks may increase the rate of evidence-based practice (EBP) adoption and improve outcomes for patients with opioid dependence.
authors.forename: Erin L
authors.initials: EL
authors.lastname: Winstanley
authors.forename: Greg S
authors.initials: GS
authors.lastname: Brigham
authors.forename: Dean
authors.initials: D
authors.lastname: Babcock
authors.forename: Theresa
authors.initials: T
authors.lastname: Winhusen
mesh_terms: D000701:Analgesics, Opioid / Q000009:adverse effects* / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D055812:Community-Based Participatory Research; D062787:Drug Overdose / Q000401:mortality / Q000517:prevention & control; D005260:Female; D006801:Humans; D054577:National Institute on Drug Abuse (U.S.); D009820:Ohio; D009293:Opioid-Related Disorders / Q000188:drug therapy* / Q000401:mortality / Q000517:prevention & control; D063487:Prescription Drug Misuse / Q000401:mortality* / Q000517:prevention & control; D011785:Quality Assurance, Health Care / Q000379:methods*; D016320:Substance Abuse Treatment Centers / Q000379:methods / Q000458:organization & administration*; D014481:United States / Q000453:epidemiology
chemical_list: D000701:Analgesics, Opioid