title: Population correlates of circulating mercury levels in Korean adults: the Korea National Health and Nutrition Examination Survey IV.
abstract: BACKGROUND
  Prior studies focused on bioaccumulation of mercury (Hg) and on large, long-lived fish species as the major environmental source of Hg, but little is known about consumption of small-sized fish or about non-dietary determinants of circulating Hg levels. The purpose of this study was to evaluate whole blood mercury concentration (WBHg) and its major dietary and non-dietary correlates in Korean adults.
  
  
  METHODS
  We analyzed cross-sectional data from 3,972 (male = 1,994; female = 1,978) participants who completed the Korean National Health and Nutrition Examination Survey IV, 2008 to 2009. Relevant factors included diet, geographic location of residence, demographics, and lifestyle. WBHg concentration was measured using cold-vapor atomic absorption spectrometry. Multivariable linear models assessed independent correlates of dietary and non-dietary factors for WBHg levels.
  
  
  RESULTS
  Median levels of WBHg were 5.1 μg/L in men and 3.7 μg/L in women. Higher levels of fish/shellfish intake were associated with higher levels of WBHg. Higher consumption of small-sized fish was linked to higher levels of WBHg. Non-dietary predictors of higher WBHg were being male, greater alcohol consumption, higher income and education, overweight/obesity, increasing age, and living in the southeast region.
  
  
  CONCLUSIONS
  Both dietary and non-dietary factors were associated with WBHg levels in the Korean population. There is significant geographic variation in WBHg levels; residents living in the mid-south have higher WBHg levels. We speculate that uncontrolled geographic characteristics, such as local soil/water content and specific dietary habits are involved.
authors.forename: Seongbeom
authors.initials: S
authors.lastname: Cho
authors.forename: David R
authors.initials: DR
authors.lastname: Jacobs
authors.affiliation: Department of Food and Nutrition, Yeungnam University, Gyeongsan, Gyeongbuk, Republic of Korea. kypark@ynu.ac.kr.
authors.forename: Kyong
authors.initials: K
authors.lastname: Park
mesh_terms: D000328:Adult; D000818:Animals; D003430:Cross-Sectional Studies; D004032:Diet; D005260:Female; D005399:Fishes; D005504:Food Analysis; D006801:Humans; D008297:Male; D008628:Mercury / Q000097:blood*; D008875:Middle Aged; D009749:Nutrition Surveys; D056910:Republic of Korea
chemical_list: D008628:Mercury