title: Blood gas analysis, blood saturation and chosen parameters of spirometric examination in NSCLC patients undergoing chemotherapy and pulmonary rehabilitation.
abstract: In industrialized countries lung cancer is associated with highest mortality among carcinoma. Progression of the disease is associated with diminished tolerance for physical activities, aggravated dyspnea and lowering of life quality. The aim of study was the evaluation of blood gas, blood saturation and chosen parameters of spirometric examination in NSCLC patients undergoing chemotherapy and pulmonary rehabilitation. Analysis of capillary blood was done using RapidPoint 405 Siemens device. Spirometric examination was done using PNEUMO abcMED device.
  
  
  METHODS
  Forty-nine patients with inoperable NSCLC were subjected to the examination. This included 38 men and 11 women aged between 46-75 years (mean age 63 +/- 7.5 years) who were separated into two groups: group I--25 patients undergoing standard chemotherapy (group C); group II--24 patients undergoing standard chemotherapy and pulmonary rehabilitation (group CK). All patients were subjected to blood gas analysis, blood saturation analysis and spirometric examination twice, before and after first-line chemotherapy
  
  
  RESULTS
  Increase of pO2 and SaO2 in blood, and FEV1 and FVC in spirometric examination was significantly higher in patients undergoing pulmonary rehabilitation and chemotherapy (group II) (p < 0.05) in comparison to NSCLC patients undergoing only chemotherapy (group I).
  
  
  CONCLUSIONS
  Pulmonary rehabilitation of NSCLC patients undergoing first-line chemotherapy results in improvement of indicators of blood gas, blood saturation analysis and chosen parameters of spirometric analysis. Pulmonary rehabilitation in patients with lung cancer seems to be an important form of supplementary treatment.
authors.forename: Sławomir
authors.initials: S
authors.lastname: Tokarski
authors.forename: Kamila
authors.initials: K
authors.lastname: Tokarska
authors.forename: Ewa
authors.initials: E
authors.lastname: Schwarz
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Obrebska
authors.forename: Anna
authors.initials: A
authors.lastname: Mejer
authors.forename: Jan
authors.initials: J
authors.lastname: Kowalski
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001784:Blood Gas Analysis; D002289:Carcinoma, Non-Small-Cell Lung / Q000097:blood* / Q000188:drug therapy / Q000534:rehabilitation*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood* / Q000188:drug therapy / Q000534:rehabilitation*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood*; D013147:Spirometry
chemical_list: D000970:Antineoplastic Agents; D010100:Oxygen