title: Megakaryocytic irreversible P-TEFb activation.
authors.affiliation: Department of Pathology; University of Virginia School of Medicine; Charlottesville, VA USA.
authors.forename: Kamaleldin E
authors.initials: KE
authors.lastname: Elagib
authors.affiliation: Department of Pathology; University of Virginia School of Medicine; Charlottesville, VA USA.
authors.forename: Adam N
authors.initials: AN
authors.lastname: Goldfarb
mesh_terms: D000818:Animals; D002154:Calpain / Q000502:physiology*; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D050982:GATA1 Transcription Factor / Q000235:genetics*; D006801:Humans; D007938:Leukemia / Q000473:pathology*; D008533:Megakaryocytes / Q000473:pathology*; D009154:Mutation / Q000235:genetics*; D042925:Positive Transcriptional Elongation Factor B / Q000378:metabolism*; D017411:Ribonucleoproteins, Small Nuclear / Q000378:metabolism*
chemical_list: D050982:GATA1 Transcription Factor; D017411:Ribonucleoproteins, Small Nuclear; D042925:Positive Transcriptional Elongation Factor B; D002154:Calpain
keywords: 7SK snRNP; P-TEFb; calpain 2; megakaryocyte; morphogenesis