title: Response to letter regarding article, "Archetypal Arg169Cys mutation in NOTCH3 does not drive the pathogenesis in cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy via a loss-of-function mechanism".
authors.affiliation: INSERM, U1161, Paris, France.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Cognat
authors.affiliation: CERVCO, Groupe Hospitalier Saint-Louis Lariboisière-Fernand-Widal, Assistance Publique - Hôpitaux de Paris, Paris, France.
authors.forename: Dominique
authors.initials: D
authors.lastname: Hervé
authors.affiliation: INSERM, U1161, Paris, France.
authors.forename: Anne
authors.initials: A
authors.lastname: Joutel
mesh_terms: D000818:Animals; D046589:CADASIL / Q000235:genetics*; D009154:Mutation / Q000235:genetics* / Q000502:physiology*; D051880:Receptors, Notch / Q000235:genetics* / Q000502:physiology*
chemical_list: D051880:Receptors, Notch