title: Erythropoiesis-stimulating agents for the treatment of chemotherapy-induced anemia: comparisons from real-world clinical experience.
abstract: BACKGROUND
  The purpose of this paper is to report real-world data on the relative effectiveness of a biosimilar erythropoiesis-stimulating agent (ESA; Binocrit(®)), and other available ESAs for the treatment of chemotherapy-induced anemia.
  
  
  METHODS
  Data were collected retrospectively from single centers in Spain (n=284) and Germany (n=145). Hemoglobin outcomes, transfusion requirements, and serious drug-related adverse events were assessed for each ESA.
  
  
  RESULTS
  Hemoglobin outcomes and transfusion requirements were generally similar in the different ESA treatment groups assessed. No serious drug-related adverse events were recorded in any of the treatment groups.
  
  
  CONCLUSIONS
  These data confirm the real-world effectiveness and safety of a biosimilar ESA (Binocrit(®)) for the treatment of cancer patients with chemotherapy-induced anemia.
authors.affiliation: Hospital Universitario 12 de Octubre, Ctra Andalucía, Madrid, Spain.
authors.forename: Analia
authors.initials: A
authors.lastname: Rodriguez Garzotto
authors.affiliation: Hospital Universitario 12 de Octubre, Ctra Andalucía, Madrid, Spain.
authors.forename: Susana
authors.initials: S
authors.lastname: Cortijo Casacajares
authors.affiliation: Hospital Universitario 12 de Octubre, Ctra Andalucía, Madrid, Spain.
authors.forename: Cristina
authors.initials: C
authors.lastname: Pernaut
authors.affiliation: Hospital Universitario 12 de Octubre, Ctra Andalucía, Madrid, Spain.
authors.forename: Gustavo Javier
authors.initials: GJ
authors.lastname: Ruiz Ares
authors.affiliation: 1Hospital Universitario 12 de Octubre, Ctra Andalucía, Madrid, Spain.
authors.forename: Irene
authors.initials: I
authors.lastname: Otero Blas
authors.affiliation: Zentralklinikum Suhl, Suhl, Germany.
authors.forename: Oliver
authors.initials: O
authors.lastname: Heine
authors.affiliation: Sandoz International GmbH, Holzkirchen, Germany.
authors.forename: Matthew
authors.initials: M
authors.lastname: Turner
authors.affiliation: Sandoz Farmaceutica SA, Madrid, Spain.
authors.forename: Francisco
authors.initials: F
authors.lastname: Rebollo Laserna
authors.affiliation: Hospital Universitario 12 de Octubre, Ctra Andalucía, Madrid, Spain.
authors.forename: Hernan
authors.initials: H
authors.lastname: Cortes Funes
authors.affiliation: Frauenarztpraxis, Hildburghausen, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Lorenz
keywords: biosimilar; chemotherapy-induced anemia; erythropoiesis-stimulating agents