title: Full-genome sequence of human betacoronavirus 2c jordan-n3/2012 after serial passage in Mammalian cells.
abstract: Middle East respiratory syndrome coronavirus (MERS-CoV) is the etiologic agent of a highly lethal pneumonia. Here, we report the full-genome sequence of the Jordan-N3/2012 strain after serial passage in two distinct mammalian cell lines. The genome exhibits noteworthy stability, which may inform the development of vaccines and therapeutics used to treat infection with this virus.
authors.affiliation: kenneth.frey@med.navy.mil gabriel.defang@med.navy.mil.
authors.forename: Kenneth G
authors.initials: KG
authors.lastname: Frey
authors.forename: Cassie L
authors.initials: CL
authors.lastname: Redden
authors.forename: Kimberly A
authors.initials: KA
authors.lastname: Bishop-Lilly
authors.affiliation: National Institutes of Health, National Institute of Allergy and Infectious Diseases, Integrated Research Facility, Fort Detrick, Maryland, USA.
authors.forename: Reed
authors.initials: R
authors.lastname: Johnson
authors.affiliation: National Institutes of Health, National Institute of Allergy and Infectious Diseases, Integrated Research Facility, Fort Detrick, Maryland, USA.
authors.forename: Lisa E
authors.initials: LE
authors.lastname: Hensley
authors.affiliation: Naval Medical Research Center, Viral and Rickettsial Diseases Department, Silver Spring, Maryland, USA.
authors.forename: Kanakatte
authors.initials: K
authors.lastname: Raviprakash
authors.forename: Thomas
authors.initials: T
authors.lastname: Luke
authors.affiliation: Naval Medical Research Center, Viral and Rickettsial Diseases Department, Silver Spring, Maryland, USA.
authors.forename: Tad
authors.initials: T
authors.lastname: Kochel
authors.affiliation: Naval Medical Research Center, NMRC-Frederick, Fort Detrick, Maryland, USA.
authors.forename: Vishwesh P
authors.initials: VP
authors.lastname: Mokashi
authors.affiliation: Viral and Zoonotic Diseases Research Program, U.S. Naval Medical Research Unit 3, Abbassia, Cairo, Egypt kenneth.frey@med.navy.mil gabriel.defang@med.navy.mil.
authors.forename: Gabriel N
authors.initials: GN
authors.lastname: Defang