title: ANCA associated vasculitis and chronic lymphocytic leukemia: a rare association.
abstract: The aim of the present work is to discuss the report of a patient who had simultaneous diagnosis of two rare diseases, vasculitis related to antineutrophil cytoplasmic antibodies and chronic lymphocytic leukemia. Both are diseases that may be multisystemic and thus cause diagnostic confusion. In this case, the patient had renal, pulmonary, hematological, and ocular symptoms, which could be secondary to vasculitis both as to leukemia. With the aid of imaging studies, pathological studies, immunohistochemistry and immunophenotyping, we conclude that it was a combination of the two diseases. There are other reports in literature of this association, however, with pANCA positive, this is the first report of chronic lymphocytic leukemia associated with cANCA positive vasculitis.
authors.affiliation: Irmandade Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brasil.
authors.forename: Juliana Miranda
authors.initials: JM
authors.lastname: de Lucena
authors.affiliation: Irmandade Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brasil.
authors.forename: Amanda Garbin
authors.initials: AG
authors.lastname: Callegari
authors.affiliation: Irmandade Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brasil.
authors.forename: Fabiola Brasil
authors.initials: FB
authors.lastname: Barbosa
authors.affiliation: Irmandade Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brasil.
authors.forename: José Celso Giordan Cavalcanti
authors.initials: JC
authors.lastname: Sarinho
authors.affiliation: Irmandade Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brasil.
authors.forename: Renielly
authors.initials: R
authors.lastname: Casagrande
authors.affiliation: Faculdade de Ciências Médicas da Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brasil.
authors.forename: Branca Dias Batista
authors.initials: BD
authors.lastname: de Souza
mesh_terms: D056648:Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / Q000150:complications*; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications*; D008297:Male; D008875:Middle Aged