title: Facile in situ synthesis of hydrophilic RGO-CD-Ag supramolecular hybrid and its enhanced antibacterial properties.
abstract: In this study, a novel hydrophilic RGO-CD-Ag hybrid with the supramolecular β-cyclodextrin (CD) as a conjugation interface was fabricated successfully by a facile in situ synthesis process. The results of several characterizations confirmed that the in situ reaction provided a straightforward approach to deposit the CD wrapped Ag nanoparticles onto the CD chemical functionalized RGO sheets through the head-to-head H-bond interactions between the linker CD molecules. Moreover, it was also found that the CD interface that existed indeed influences the structure and performances of RGO-CD-Ag nanocomposite. The analysis of the static contact angle revealed that the surface property of the hybrid could be transformed from hydrophobic to hydrophilic feature, which highly improved the aqueous dispersibility. And then, the bactericidal test of RGO-CD-Ag was demonstrated and clearly showed the strongest antibacterial activity against Gram-negative and Gram-positive bacteria among all samples. In short, this method may readily provide a new family of supramolecular based materials expected to find applications beyond the bactericidal field.
authors.affiliation: Center of Special Materials and Technology, Fudan University, Shanghai 200433, China; Department of Materials Science, Fudan University, Shanghai 200433, China.
authors.forename: Tie
authors.initials: T
authors.lastname: Li
authors.affiliation: Center of Special Materials and Technology, Fudan University, Shanghai 200433, China; Department of Materials Science, Fudan University, Shanghai 200433, China.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Shen
authors.affiliation: Center of Special Materials and Technology, Fudan University, Shanghai 200433, China.
authors.forename: Na
authors.initials: N
authors.lastname: Li
authors.affiliation: Center of Special Materials and Technology, Fudan University, Shanghai 200433, China; Department of Materials Science, Fudan University, Shanghai 200433, China. Electronic address: mxye@fudan.edu.cn.
authors.forename: Mingxin
authors.initials: M
authors.lastname: Ye
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D006108:Graphite / Q000737:chemistry; D057927:Hydrophobic and Hydrophilic Interactions; D053768:Metal Nanoparticles / Q000737:chemistry; D053761:Nanocomposites / Q000737:chemistry; D012834:Silver / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared; D013059:Spectrum Analysis, Raman; D013499:Surface Properties; D047392:beta-Cyclodextrins / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D047392:beta-Cyclodextrins; D012834:Silver; D006108:Graphite; C031215:betadex
keywords: Antibacterial; Graphene; In situ; Supramolecular interface; β-Cyclodextrin