title: Synthesis and characterization of modified starch/polybutadiene as novel transdermal drug delivery system.
abstract: Transdermal drug delivery systems are topically administered medicaments in the form of patches that deliver drugs for systemic effects at a predetermined and controlled rate. It works very simply in which drug is applied inside the patch and it is worn on skin for long period of time. Polymer matrix, drug, permeation enhancers are the main components of transdermal drug delivery systems. The objective of the present study was to develop the modified starch and 1,4-cis polybutadiene nanoparticles as novel polymer matrix system. We have been studied the properties of a novel transdermal drug delivery system with clonidine as drug model.
authors.affiliation: Nanostructured Materials Synthesis Lab., International Research Institute of Arian Chemie Gostar, Tabriz, Iran. Electronic address: saboktakin123@gmail.com.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Saboktakin
authors.affiliation: Institute of Petrochemical Processes of Azerbaijan National Academy of Sciences, 30, Khodjaly av., Baku AZ 1025, Azerbaijan.
authors.forename: Shahab
authors.initials: S
authors.lastname: Akhyari
authors.affiliation: Institute of Petrochemical Processes of Azerbaijan National Academy of Sciences, 30, Khodjaly av., Baku AZ 1025, Azerbaijan.
authors.forename: Fizuli A
authors.initials: FA
authors.lastname: Nasirov
mesh_terms: D000279:Administration, Cutaneous; D002070:Butadienes / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic; D004337:Drug Carriers / Q000138:chemical synthesis* / Q000737:chemistry*; D020724:Elastomers / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D053758:Nanoparticles / Q000737:chemistry; D013213:Starch / Q000737:chemistry*
chemical_list: D002070:Butadienes; D004337:Drug Carriers; D020724:Elastomers; C028834:polybutadiene; D013213:Starch
keywords: Drug delivery; Modified starch; Polybutadiene; Transdermal