title: The contribution of ¹⁸F-FDG PET/CT in a patient with cutaneous metastases of squamous cell carcinoma of the penis.
abstract: A 61-year-old patient was diagnosed with squamous cell carcinoma of the penis (SCCP) and treated with partial penectomy (pT1,N0,M0,G2). Seven months later, a palpable adenopathy was found in the left inguinal region. An (18)F-FDG PET/CT exploration showed hypermetabolic lymphadenopathies in inguinal, pelvic, retroperitoneal regions, in both lung hila and in the left supraclavicular regions. At the end of the 4th cycle of chemotherapy (cisplatin+5FU) the patient developed numerous skin metastases at the root of the left thigh and a pleural effusion in the right lung. In a new exploration with (18)F-FDG PET/CT the number, size and metabolic activity of known lymphadenopathies decreased. Right pleural carcinomatosis and intense FDG uptake in cutaneous metastases were observed. Weeks later, the patient died. (18)F-FDG-PET/TC may be useful in patients with SCCP and metastatic inguinal lymphadenopathies, to assess the response to chemotherapy and to detect other unsuspected metastases in the rare cases of cutaneous metastases.
authors.affiliation: Unidad PET/TAC, Grupo Hospitalario Quirón La Floresta, Zaragoza, Spain. Electronic address: jbanzoma@unizar.es.
authors.forename: J
authors.initials: J
authors.lastname: Banzo
authors.affiliation: Unidad PET/TAC, Grupo Hospitalario Quirón La Floresta, Zaragoza, Spain.
authors.forename: M A
authors.initials: MA
authors.lastname: Ubieto
authors.affiliation: Servicio de Medicina Nuclear, HCU Lozano Blesa, Zaragoza, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Andrés
authors.affiliation: Servicio de Medicina Nuclear, HCU Lozano Blesa, Zaragoza, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Tardín
authors.affiliation: Servicio de Medicina Nuclear, HCU Lozano Blesa, Zaragoza, Spain.
authors.forename: E F
authors.initials: EF
authors.lastname: Rambalde
authors.affiliation: Servicio de Medicina Nuclear, HCU Lozano Blesa, Zaragoza, Spain.
authors.forename: L F
authors.initials: LF
authors.lastname: Cancer
authors.affiliation: Servicio de Medicina Nuclear, HCU Lozano Blesa, Zaragoza, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Razola
authors.affiliation: Servicio de Medicina Nuclear, HCU Lozano Blesa, Zaragoza, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Prats
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000556:secondary*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D010412:Penile Neoplasms / Q000473:pathology*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000556:secondary*; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: (18)F-FDG PET/CT; (18)F-FDG PET/TC; Carcinoma de células escamosas de pene; Cutaneous metastases; Metástasis cutáneas; Squamous cell carcinoma of the penis