title: Current situation and associated factors of withdrawing or withholding life support to patients in an intensive care unit of cancer center in China.
abstract: OBJECTIVE
  To investigate the current situation and analyze the associated factors of withdrawing or withholding life support in the intensive care unit (ICU) of our cancer center.
  
  
  METHODS
  Three hundred and twenty-two cancer patients in critical status were admitted to our ICU in 2010 and 2011. They were included in the study and were classified into two groups: withdrawing or withholding life support (WWLS), and full life support (FLS). Demographic information and clinical data were collected and compared between the two groups. Factors associated with withdrawing or withholding life support were analyzed with univariate and multivariate logistic regression analysis.
  
  
  RESULTS
  Eighty-two of the 322 cases (25.5% of all) made the decisions to withdraw or withhold life support. Emergency or critical condition at hospital admission, higher scores of Acute Physiology and Chronic Health Evaluation II (APACHE II) in 12 hours after ICU admission, financial difficulties and humanistic care requirements are important factors associated with withdrawing or withholding life support.
  
  
  CONCLUSIONS
  Withdrawing or withholding life support is not uncommon in critically ill cancer patients in China. Characteristics and associated factors of the decision-making are related to the current medical system, medical resources and traditional culture of the country.
authors.affiliation: Intensive Care Unit, Sun Yat-sen University Cancer Center, Guangzhou, China.
authors.forename: Qingyu
authors.initials: Q
authors.lastname: Zhao
authors.affiliation: Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
authors.forename: Xiaodan
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Intensive Care Unit, Sun Yat-sen University Cancer Center, Guangzhou, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Fang
authors.affiliation: Intensive Care Unit, Sun Yat-sen University Cancer Center, Guangzhou, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Gong
authors.affiliation: Intensive Care Unit, Sun Yat-sen University Cancer Center, Guangzhou, China.
authors.forename: Baochun
authors.initials: B
authors.lastname: Gu
authors.affiliation: Intensive Care Unit, Sun Yat-sen University Cancer Center, Guangzhou, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Ma
mesh_terms: D002681:China / Q000453:epidemiology; D006306:Health Surveys / Q000379:methods*; D006801:Humans; D007362:Intensive Care Units / Q000941:ethics*; D008020:Life Support Care / Q000941:ethics* / Q000706:statistics & numerical data; D016015:Logistic Models; D009369:Neoplasms / Q000453:epidemiology* / Q000628:therapy*; D018709:Statistics, Nonparametric; D028761:Withholding Treatment / Q000941:ethics* / Q000706:statistics & numerical data