title: Prevalence and Incidence of Syphilis among Volunteer Blood Donors in Israel.
abstract: Data of 1,290,222 volunteer blood donors, in a 5-year period, was analyzed for prevalence and incidence of syphilis. Subsequent testing of donations positive in Treponema pallidum hemagglutination assay included Venereal Disease Research Laboratory and fluorescent Treponemal antibody absorption. Stepwise logistic regression model was used to identify positive syphilis serology. Prevalence of syphilis was 47 : 100,000, similar in men and women and increased significantly with age (P < 0.001). Native Israelis had the lowest prevalence rate of syphilis (21 : 100,000), while a significantly higher prevalence was found among immigrants from Africa, Eastern Europe, and South America (odds ratios of 19.0, 10.8, and 7.3, resp., P < 0.001 for each). About 33.2% of the seropositive donors had evidence of recent infection, and 66.8% had past infections. Incidence rate reached 8 : 100,000 person-years. Coinfection with HIV, HCV, and HBV was calculated as 8%, 1.88%, and 0.37% for positive donations, respectively. The data support the need to continue screening blood donors in Israel for syphilis and employ preventive measures to populations at risk, in order to improve public health, blood safety, and quality. A subsequent study to assess blood donors' knowledge, attitude, and behavior is planned. In times of global migration this information may be useful to blood services worldwide.
authors.affiliation: Department of Dermatology, Hadassah-Hebrew University Hospital, P.O. Box 12018, Jersalem, Israel.
authors.forename: Leibovici
authors.initials: L
authors.lastname: Vera
authors.affiliation: Brown School of Public Health, Hadassah University Hospital, Jersalem, Israel.
authors.forename: Donchin
authors.initials: D
authors.lastname: Milka
authors.affiliation: Private Practice, P.O. Box 84027, 90805 Mevaseret Zion, Israel.
authors.forename: Strauss-Liviatan
authors.initials: SL
authors.lastname: Nurith
authors.affiliation: Magen David Adom National Blood Services, 52621 Ramat Gan, Israel.
authors.forename: Shinar
authors.initials: S
authors.lastname: Eilat