title: Nitrogen-Vacancy color center in diamond-emerging nanoscale applications in bioimaging and biosensing.
abstract: Nitrogen-Vacancy (NV) color center in diamond is a flourishing research area that, in recent years, has displayed remarkable progress. The system offers great potential for realizing futuristic applications in nanoscience, benefiting a range of fields from bioimaging to quantum-sensing. The ability to image single NV color centers in a nanodiamond and manipulate NV electron spin optically under ambient condition is the main driving force behind developments in nanoscale sensing and novel imaging techniques. In this article we discuss current status on the applications of fluorescent nanodiamonds (FND) for optical super resolution nanoscopy, magneto-optical (spin-assisted) sub-wavelength localization and imaging. We present emerging applications such as single molecule spin imaging, nanoscale imaging of biomagnetic fields, sensing molecular fluctuations and temperatures in live cellular environments. We summarize other current advances and future prospects of NV diamond for imaging and sensing pertaining to bio-medical applications.
authors.affiliation: Max-Planck Research Group Nanoscale Spin Imaging, Max-Planck Institute for Biophysical Chemistry, Göttingen, Germany; Center for Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), Göttingen, Germany. Electronic address: gbalasu@mpibpc.mpg.de.
authors.forename: Gopalakrishnan
authors.initials: G
authors.lastname: Balasubramanian
authors.affiliation: Max-Planck Research Group Nanoscale Spin Imaging, Max-Planck Institute for Biophysical Chemistry, Göttingen, Germany.
authors.forename: Andrii
authors.initials: A
authors.lastname: Lazariev
authors.affiliation: Max-Planck Research Group Nanoscale Spin Imaging, Max-Planck Institute for Biophysical Chemistry, Göttingen, Germany.
authors.forename: Sri Ranjini
authors.initials: SR
authors.lastname: Arumugam
authors.affiliation: Max-Planck Research Group Nanoscale Spin Imaging, Max-Planck Institute for Biophysical Chemistry, Göttingen, Germany.
authors.forename: De-Wen
authors.initials: DW
authors.lastname: Duan
mesh_terms: D000818:Animals; D015374:Biosensing Techniques; D003116:Color; D006801:Humans; D057054:Molecular Imaging; D053758:Nanoparticles / Q000737:chemistry*; D009584:Nitrogen / Q000737:chemistry*
chemical_list: D009584:Nitrogen