title: Aggressive middle turbinate osteoblastoma with intracranial extension: a case report.
abstract: BACKGROUND
  Osteoblastoma is an uncommon benign bone tumor that accounts for 1 percent of all primary bone tumors. About 30 to 40 percent of all osteoblastoma cases involve the spine. Osteoblastoma involving the nasal cavity is rare, with only 11 reported cases in the English-language literature, while only four cases of turbinate osteoblastoma have been described.
  
  
  METHODS
  We report an unusual case of middle turbinate osteoblastoma associated with right-sided nasal obstruction and severe headache in a 14-year-old Caucasian girl. The tumor involved the right middle turbinate, complete anterior and incomplete posterior ethmoidal cells, and the frontal sinus ostium. Cribriform lamina was, in the most part, consumed by the tumor growth, while the skull base was mostly of normal bone structure.
  
  
  CONCLUSIONS
  To the best of our knowledge, this is the first case of middle turbinate osteoblastoma with intracranial spread. Surgical treatment is the only therapeutic option for osteoblastoma.
authors.affiliation: Department of Othorinolaryngology, University Hospital Split, Spinčićeva 1, 21000 Split, Croatia. drasko.cikojevic@st.t-com.hr.
authors.forename: Draško
authors.initials: D
authors.lastname: Cikojević
authors.forename: Zaviša
authors.initials: Z
authors.lastname: Colović
authors.forename: Bernarda
authors.initials: B
authors.lastname: Lozić
authors.forename: Marisa
authors.initials: M
authors.lastname: Klančnik
mesh_terms: D000293:Adolescent; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D005004:Ethmoid Bone / Q000473:pathology*; D005260:Female; D006261:Headache / Q000209:etiology; D006801:Humans; D015508:Nasal Obstruction / Q000209:etiology; D009361:Neoplasm Invasiveness; D009669:Nose Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D018215:Osteoblastoma / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D010255:Paranasal Sinus Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D014420:Turbinates / Q000473:pathology*