title: Periodontal considerations in a patient with glucose-6-phosphate dehydrogenase deficiency with associated pancytopenia: A rare case report.
abstract: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme defect in humans. G6PD deficiency is widely distributed in tropical and subtropical parts of the world and a conservative estimate is that at least 500 million people have a G6PD deficient gene. In several of these areas, the frequency of a G6PD deficiency gene may be as high as 20% or more. The vast majority of people with G6PD deficiency remain clinically asymptomatic throughout their lifetime. However, all of them have an increased risk of developing neonatal jaundice and a risk of developing acute hemolytic anemia when challenged by a number of oxidative agents. The most important treatment measure is prevention: Avoidance of the drugs and foods that cause hemolysis.
authors.affiliation: Department of Periodontology, Government Dental College and Hospital, Amritsar, Punjab, India.
authors.forename: Harinder
authors.initials: H
authors.lastname: Gupta
authors.affiliation: Department of Periodontology, Government Dental College and Hospital, Amritsar, Punjab, India.
authors.forename: Ruchika
authors.initials: R
authors.lastname: Arora
authors.affiliation: Department of Periodontology, Government Dental College and Hospital, Amritsar, Punjab, India.
authors.forename: Monika
authors.initials: M
authors.lastname: Kamboj
keywords: Bone loss; glucose-6-phosphate dehydrogenase deficiency; pancytopenia