title: [Comparison of short- and long-term efficacy of three procedures in postoperative digestive tract reconstruction for upper gastric cancer].
abstract: OBJECTIVE
  To compare the short- and long-term efficacy of three different procedures used for digestive tract reconstruction after radical gastrectomy for upper gastric cancer.
  
  
  METHODS
  Clinical data of 191 patients with upper gastric cancer undergoing radical gastrectomy in the Fujian Provincial Hospital between January 2000 and December 2012 were analyzed retrospectively. Surgical procedures were classified as total gastrectomy followed by Roux-en-Y esophagojejunostomy (TG-RY, n=123), proximal gastrectomy followed by esophagogastrostomy (PG-EG, n=40), and proximal gastrectomy followed by jejunal interposition (PG-JI, n=28). Clinicopathological characteristics, perioperative and long-term outcomes were compared among the three groups.
  
  
  RESULTS
  The operative time was shorter (178 vs. 248 and 224 min, P<0.05), and the intraoperative blood loss was less (194 vs. 323 and 265 ml, P<0.05) in PG-EG group than those in TG-RY and PG-JI groups. Early postoperative complications and hospital stay were comparable (both P>0.05). With respect to gastrectomy-associated symptoms, reflux and heartburn were more frequent in PG-EG patients, while dumpling syndrome was more frequent after TG-RY. Postoperative weight loss was not significantly different among three procedures (P>0.05), however, hemoglobin and serum albumin levels were lower in TG-RY patients (both P<0.05). The 5-year survival rate was similar (P>0.05).
  
  
  CONCLUSIONS
  Surgeons need to choose the proper procedure according to tumor features and patient condition. PG-JI should be the first choice in terms of fewer complaints and better nutrition. TG-RY tends to be used for larger and more advanced tumors. PG-EG is the most minimally invasive procedure and thus may be suitable for older and high-risk patients.
authors.affiliation: Department of Gastrointestinal Surgery, Fujian Provincial Hospital, Provincial Clinical College, Fujian Medical University, Fuzhou 350001, China. yzf665257@163.com.
authors.forename: Changqing
authors.initials: C
authors.lastname: Zeng
authors.forename: Liangxiang
authors.initials: L
authors.lastname: Huang
authors.forename: Linhao
authors.initials: L
authors.lastname: Chen
authors.forename: Haixiao
authors.initials: H
authors.lastname: Huang
authors.forename: Yu
authors.initials: Y
authors.lastname: Zheng
authors.forename: Liangjie
authors.initials: L
authors.lastname: Chi
mesh_terms: D000368:Aged; D000713:Anastomosis, Roux-en-Y / Q000379:methods; D000714:Anastomosis, Surgical / Q000379:methods*; D013505:Digestive System Surgical Procedures / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000601:surgery*; D016896:Treatment Outcome