title: [Correlation between end-tidal carbon dioxide and partial pressure of arterial carbon dioxide in ventilated newborns].
abstract: OBJECTIVE
  To study the correlation between end-tidal carbon dioxide (PetCO2) and partial pressure of arterial carbon dioxide (PaCO2) in ventilated newborns.
  
  
  METHODS
  Thirty-one ventilated newborn underwent mainstream PetCO2 monitoring; meanwhile, arterial blood gas analysis was performed. The correlation and consistency between PetCO2 and PaCO2 were assessed.
  
  
  RESULTS
  A total of 85 end-tidal and arterial CO2 pairs were obtained from 31 ventilated newborns. The mean PetCO2 (41±10 mm Hg) was significantly lower than the corresponding mean PaCO2 (46±11 mm Hg) (P<0.01). There was a significant positive correlation between PetCO2 and PaCO2 (r=0.92, P<0.01). The overall PetCO2 bias was 5.1±4.3 mm Hg (95% limits of consistency, -3.3 to 13.6 mmHg), and 5% (4/85) of the points were beyond the 95%CI. When the oxygenation index (OI) was less than 300 mm Hg (n=48), there was a significant positive correlation between PetCO2 and PaCO2 (r=0.85, P<0.01); the PetCO2 bias was 5.9±4.3 mm Hg (95% limits of consistency, -2.6 to 14.5 mm Hg), and 4.2% (2/48) of the points were beyond the 95%CI. When the OI was more than 300 mm Hg (n=37), there was also a significant positive correlation between PetCO2 and PaCO2 (r=0.91, P<0.01); the PetCO2 bias was 4.1±4.1 mm Hg (95% limits of consistency, -3.9 to 12.1 mm Hg), and 5% (2/37) of the points were beyond the 95%CI.
  
  
  CONCLUSIONS
  There is a good correlation and consistency between PetCO2 and PaCO2 in ventilated newborns.
authors.affiliation: Department of Neonatology, Shenzhen Children's Hospital, Shenzhen 518026, China. szfjx2013@hotmail.com.
authors.forename: Jin-Xing
authors.initials: JX
authors.lastname: Feng
authors.forename: Xiao-Hong
authors.initials: XH
authors.lastname: Liu
authors.forename: Hui-Jun
authors.initials: HJ
authors.lastname: Huang
authors.forename: Zhen-Zhu
authors.initials: ZZ
authors.lastname: Yu
authors.forename: Hui
authors.initials: H
authors.lastname: Yang
authors.forename: Liu-Fang
authors.initials: LF
authors.lastname: He
mesh_terms: D002245:Carbon Dioxide / Q000097:blood*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010313:Partial Pressure; D012121:Respiration, Artificial
chemical_list: D002245:Carbon Dioxide