title: Microwave ablation of a large renal aspergilloma.
abstract: Increasing numbers of immunocompromised patients have led to a corresponding rise in the incidence of invasive Aspergillus infections. Despite advances in antifungal therapy coupled with reduction in immunosuppression, invasive aspergillosis is associated with significant morbidity and mortality. Although surgical debulking has proven effective in difficult-to-treat cases, patient comorbidities may prevent such intervention. Non-invasive alternatives to surgery are needed. Microwave ablation has many advantages over other ablative techniques, including convection profile, faster heating time, and higher intra-lesion temperatures, which may be associated with greater therapeutic efficacy. We report a case of microwave ablation as an adjunct to medical therapy in angioinvasive renal aspergilloma.
authors.affiliation: Division of Infectious Diseases, The University of Kansas Medical Center, Kansas City, Kansas, USA.
authors.forename: S
authors.initials: S
authors.lastname: Waller
authors.forename: Z
authors.initials: Z
authors.lastname: Raglow
authors.forename: S
authors.initials: S
authors.lastname: Lemons
authors.forename: P
authors.initials: P
authors.lastname: Johnson
authors.forename: A
authors.initials: A
authors.lastname: Eid
authors.forename: T
authors.initials: T
authors.lastname: Schmitt
authors.forename: J
authors.initials: J
authors.lastname: Smothers
authors.forename: M
authors.initials: M
authors.lastname: O'Neil
authors.forename: R
authors.initials: R
authors.lastname: Gilroy
mesh_terms: D055011:Ablation Techniques / Q000379:methods*; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D007674:Kidney Diseases / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery*; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008872:Microwaves / Q000627:therapeutic use*; D008875:Middle Aged
chemical_list: D000935:Antifungal Agents
keywords: aspergilloma; invasive aspergillosis; liver transplantation; microwave ablation