title: Physiopathological aspects of the subclinical alterations of thyroid function associated with acute coronary syndromes.
abstract: The subclinical modification of thyroid function represents an important risk factor for the development of acute coronary syndromes, neglected up to this day. Knowledge of the physiopathological processes implicated in the alteration of thyroid function that induces cardiovascular dysfunction is a necessity for the understanding of the phenomena and for the finding of the adequate therapeutic solutions. While recognizing the thyroid dysfunction as a modifiable risk factor for the acute coronary syndrome, we encountered a new challenge for the clinical research regarding its implications. The ability to manage the altered thyroid homeostasis may represent a new stage of prevention at a population level for the reduction of the cardiac risk, a stage which implies a risk factor that may remain clinically mute for a long period of time if left undiagnosed, however influencing the development of the acute coronary syndromes.
authors.affiliation: 1st Internal Medicine and Cardiology Department, "Sfantul Pantelimon" Clinical Emergency Hospital Bucharest ; "Carol Davila" University of Medicine and Pharmacy Bucharest.
authors.forename: C S
authors.initials: CS
authors.lastname: Stamate
authors.affiliation: 1st Internal Medicine and Cardiology Department, "Sfantul Pantelimon" Clinical Emergency Hospital Bucharest ; "Carol Davila" University of Medicine and Pharmacy Bucharest.
authors.forename: A M
authors.initials: AM
authors.lastname: Andronescu
authors.affiliation: 1st Internal Medicine and Cardiology Department, "Sfantul Pantelimon" Clinical Emergency Hospital Bucharest ; "Carol Davila" University of Medicine and Pharmacy Bucharest.
authors.forename: A C
authors.initials: AC
authors.lastname: Nechita
authors.affiliation: 1st Internal Medicine and Cardiology Department, "Sfantul Pantelimon" Clinical Emergency Hospital Bucharest.
authors.forename: C
authors.initials: C
authors.lastname: Delcea
authors.affiliation: 1st Internal Medicine and Cardiology Department, "Sfantul Pantelimon" Clinical Emergency Hospital Bucharest.
authors.forename: E M
authors.initials: EM
authors.lastname: Mihu
authors.affiliation: 1st Internal Medicine and Cardiology Department, "Sfantul Pantelimon" Clinical Emergency Hospital Bucharest ; "Carol Davila" University of Medicine and Pharmacy Bucharest.
authors.forename: M M
authors.initials: MM
authors.lastname: Vintila
mesh_terms: D054058:Acute Coronary Syndrome / Q000503:physiopathology*; D006801:Humans; D012307:Risk Factors; D013961:Thyroid Gland / Q000473:pathology* / Q000503:physiopathology*
keywords: acute coronary syndrome; cardiac risk factor; subclinical thyroid dysfunction