title: [Oropharyngeal cancer].
abstract: Oropharyngeal carcinomas, contrary to other head and neck carcinomas are of increasing frequency, mostly due to a frequent association with human papillomavirus infection. Pluridisciplinary management is necessary. New techniques as transoral surgery or intensity-modulated radiation therapy have the potential to reduce toxicities and morbidity while offering equivalent local control rates. Early stages may be treated with single modality treatment (surgery or radiotherapy) with five-year overall survival rate exceeding 80%. Advanced stages need therapeutic associations and five-years survival rates are inferior to 40%.
authors.affiliation: CLCC François-Baclesse, Service d'ORL et de chirurgie cervico-faciale, 3, avenue du général Harris, 14076 Caen, France.
authors.forename: David
authors.initials: D
authors.lastname: Blanchard
authors.affiliation: CLCC François-Baclesse, Service d'ORL et de chirurgie cervico-faciale, 3, avenue du général Harris, 14076 Caen, France.
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Rame
authors.affiliation: CLCC François-Baclesse, Service de chirurgie maxillo-faciale, Caen, France.
authors.forename: Marie-Yolande
authors.initials: MY
authors.lastname: Louis
authors.affiliation: CLCC François-Baclesse, Service de Radiothérapie, Caen, France.
authors.forename: Bernard
authors.initials: B
authors.lastname: Gery
authors.affiliation: CLCC François-Baclesse, Service de Radiothérapie, Caen, France.
authors.forename: Carmen
authors.initials: C
authors.lastname: Florescu
authors.affiliation: CLCC François-Baclesse, Service d'ORL et de chirurgie cervico-faciale, 3, avenue du général Harris, 14076 Caen, France.
authors.forename: Dominique
authors.initials: D
authors.lastname: de Raucourt
authors.affiliation: CLCC François-Baclesse, Service d'oncologie médicale, Caen, France.
authors.forename: Radj
authors.initials: R
authors.lastname: Gervais
mesh_terms: D000428:Alcohol Drinking / Q000009:adverse effects; D006801:Humans; D060828:Induction Chemotherapy / Q000379:methods; D059351:Organ Sparing Treatments; D009959:Oropharyngeal Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D030361:Papillomavirus Infections / Q000150:complications; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects
keywords: epidemiology; human papillomavirus; oropharynx; squamous cell carcinoma; treatments