title: Understanding the added value of g-protein-coupled receptor heteromers.
abstract: G-protein-coupled receptors (GPCRs) constitute the most populated family of proteins within the human genome. Since the early sixties work on GPCRs and on GPCR-mediated signaling has led to a number of awards, the most recent being the Nobel Prize in Chemistry for 2012. The future of GPCRs research is surely based on their capacity for heteromerization. Receptor heteromers offer a series of challenges that will help in providing success in academic/basic research and translation into more effective and safer drugs.
authors.affiliation: Department Biochemistry and Molecular Biology, Faculty of Biology, University of Barcelona, Prevosti Building, Diagonal 645, 08028 Barcelona, Spain.
authors.forename: Nuria
authors.initials: N
authors.lastname: Franco
authors.affiliation: Department Biochemistry and Molecular Biology, Faculty of Biology, University of Barcelona, Prevosti Building, Diagonal 645, 08028 Barcelona, Spain.
authors.forename: Rafael
authors.identifier: 0000-0003-2549-4919
authors.initials: R
authors.lastname: Franco