title: [An analysis of risk factors for stroke in atrial fibrillation and hypertension patients].
abstract: OBJECTIVE
  To explore the independent risk factors for the 1 year stroke event in Chinese patients with atrial fibrillation (AF) and hypertension (HT).
  
  
  METHODS
  Data of AF and HT patients in the Chinese Emergency Atrial Fibrillation Registry Study were retrospectively analyzed. The eligible patients were divided into the stroke group and the non-stroke group according to the result of 1 year follow-up. The predictors for the 1 year stroke event were identified by uni- and multi-variate Cox regression analysis with the baseline and therapeutic variables.
  
  
  RESULTS
  A total of 1 118 AF and HT patients were enrolled in the study with the incidence of 1 year stroke event of 8.7%. All patients were divided into the stroke group (n = 97) and the non-stroke group (n = 1 021). Compared with the non-stroke group, more female patients were in the stroke group (68.0% vs 54.5%, P < 0.05) and the patients in the stroke group were older [(76.0 ± 9.4) years vs (71.9 ± 10.6) years, P < 0.01] with higher proportion of previous history of stroke (38.1% vs 23.8%, P < 0.01). More patients were observed on the antihypertensive treatment in the non-stroke group (91.6% vs 85.6%, P < 0.05), while more patients on statins in the stroke group (45.4% vs 34.5%, P < 0.05). Multi-variate Cox regression analysis showed that age (HR = 1.036, 95%CI 1.010-1.062), female (HR = 1.908, 95%CI 1.170-3.110), previous stroke history (HR = 1.680, 95%CI 1.084-2.603), and no antihypertensive treatment (HR = 1.955, 95%CI 1.008-3.791) were independent risk factors for the 1 year stroke event in patients with AF and HT.
  
  
  CONCLUSIONS
  Age, female, previous stroke history and no antihypertensive treatment are the independent risk factors for the 1 year stroke event in patients with AF and HT.
authors.affiliation: Emergency and Intensive Care Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Wang
authors.affiliation: Emergency and Intensive Care Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China. Email: yymwin@gmail.com.
authors.forename: Yanmin
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Emergency and Intensive Care Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Zhu
authors.affiliation: Emergency and Intensive Care Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: Xinghui
authors.initials: X
authors.lastname: Shao
authors.affiliation: Emergency and Intensive Care Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: Han
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Emergency and Intensive Care Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: Jiandong
authors.initials: J
authors.lastname: Li
authors.affiliation: Emergency and Intensive Care Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: Lisheng
authors.initials: L
authors.lastname: Liu
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001281:Atrial Fibrillation / Q000150:complications / Q000453:epidemiology*; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D020521:Stroke / Q000453:epidemiology* / Q000209:etiology