title: A prospective matched case-control study of laparoendoscopic single-site vs conventional laparoscopic myomectomy.
abstract: OBJECTIVE
  To compare operative and obstetric outcomes of laparoendoscopic single-site myomectomy (LESS-M) vs conventional laparoscopic myomectomy (LM).
  
  
  METHODS
  Prospective matched case-control study.
  
  
  METHODS
  A university hospital and a tertiary care center.
  
  
  METHODS
  Forty-five women underwent LESS-M, and 90 women underwent conventional LM.
  
  
  METHODS
  LESS-M or conventional LM.
  
  
  RESULTS
  Operative and obstetric outcomes. There were no significant differences between the 2 groups in demographic characteristics, operative time (135 vs 140 minutes), change in hemoglobin concentration (1.9 vs 1.95 g/dL), return of bowel activity (35 vs 28 hours), hospital stay (5 vs 5 days), or complication rate (11.1% vs 8.9%). Insofar as obstetric outcomes, no significant differences were observed between the 2 groups for duration of follow-up (24.4 vs 23.2 months), pregnancy rate in patients who desired pregnancy (66.7% vs 50.0%), full-term delivery rate (66.7% vs 58.3%), and time to first pregnancy after surgery (7.6 vs 10.1 months).
  
  
  CONCLUSIONS
  LESS-M is feasible and safe and has comparable obstetric outcomes to conventional LM in selected women with symptomatic myomas. However, a large prospective randomized study is needed.
authors.affiliation: Department of Obstetrics and Gynecology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
authors.forename: Ji Ye
authors.initials: JY
authors.lastname: Kim
authors.affiliation: Department of Obstetrics and Gynecology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
authors.forename: Kye Hyun
authors.initials: KH
authors.lastname: Kim
authors.affiliation: Department of Obstetrics and Gynecology, College of Medicine, Hanyang University Hospital, Seoul, Republic of Korea.
authors.forename: Joong Sub
authors.initials: JS
authors.lastname: Choi
authors.affiliation: Department of Obstetrics and Gynecology, MizMedi Hospital, Seoul, Republic of Korea. Electronic address: leemjjm@gmail.com.
authors.forename: Jung Hun
authors.initials: JH
authors.lastname: Lee
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D007889:Leiomyoma / Q000453:epidemiology / Q000601:surgery*; D061646:Operative Time; D011247:Pregnancy; D018873:Pregnancy Rate; D011446:Prospective Studies; D061685:Time-to-Pregnancy; D016896:Treatment Outcome; D063186:Uterine Myomectomy / Q000379:methods*; D014594:Uterine Neoplasms / Q000453:epidemiology / Q000601:surgery*
keywords: Gynecology; Laparoscopy; Myomectomy; Single-port surgery