title: Susceptibility of methicillin-resistant Staphylococcus aureus and enterococci to teicoplanin in Pakistan: the MRSET study.
abstract: OBJECTIVE
  To evaluate the susceptibility pattern of S. aureus and enterococci to teicoplanin using an in vitro method.
  
  
  METHODS
  Between February and November 2011, valid bacteriological samples were collected at three hospitals in three cities in Pakistan and the organism was isolated. Only samples containing S. aureus or enterococci were tested for their sensitivity to teicoplanin and various other standard antimicrobials in therapy, using the disc diffusion testing by the Kirby-Bauer method. SPSS 18 was used for statistical analysis.
  
  
  RESULTS
  Of the 401 isolates collected, a majority 293 (59.6%) were methicillin-sensitive S. aureus, while 136 (33.9%) were methicillin-resistant S. aureus; and 26 (6.5%) were enterococci. All isolates were sensitive to teicoplanin and vancomycin.
  
  
  CONCLUSIONS
  Teicoplanin had the same in vitro sensitivity as vancomycin against methicillin-sensitive S. aureus, methicillin-resistant S. aureus and enterococci in clinical isolates.
authors.forename: Altaf
authors.initials: A
authors.lastname: Ahmed
authors.forename: Shagufta
authors.initials: S
authors.lastname: Hussain
authors.forename: Tayyaba
authors.initials: T
authors.lastname: Ijaz
authors.forename: Irfan
authors.initials: I
authors.lastname: Hashemy
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D016983:Enterococcus / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D010154:Pakistan; D013203:Staphylococcal Infections / Q000188:drug therapy; D017334:Teicoplanin / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D017334:Teicoplanin