title: Relationship between the functional status scale and the pediatric overall performance category and pediatric cerebral performance category scales.
abstract: OBJECTIVE
  Functional status assessment methods are important as outcome measures for pediatric critical care studies.
  
  
  OBJECTIVE
  To investigate the relationships between the 2 functional status assessment methods appropriate for large-sample studies, the Functional Status Scale (FSS) and the Pediatric Overall Performance Category and Pediatric Cerebral Performance Category (POPC/PCPC) scales.
  
  
  METHODS
  Prospective cohort study with random patient selection at 7 sites and 8 children's hospitals with general/medical and cardiac/cardiovascular pediatric intensive care units (PICUs) in the Collaborative Pediatric Critical Care Research Network. Participants included all PICU patients younger than 18 years.
  
  
  METHODS
  Functional Status Scale and POPC/PCPC scores determined at PICU admission (baseline) and PICU discharge. We investigated the association between the baseline and PICU discharge POPC/PCPC scores and the baseline and PICU discharge FSS scores, the dispersion of FSS scores within each of the POPC/PCPC ratings, and the relationship between the FSS neurologic components (FSS-CNS) and the PCPC.
  
  
  RESULTS
  We included 5017 patients. We found a significant (P < .001) difference between FSS scores in each POPC or PCPC interval, with an FSS score increase with each worsening POPC/PCPC rating. The FSS scores for the good and mild disability POPC/PCPC ratings were similar and increased by 2 to 3 points for the POPC/PCPC change from mild to moderate disability, 5 to 6 points for moderate to severe disability, and 8 to 9 points for severe disability to vegetative state or coma. The dispersion of FSS scores within each POPC and PCPC rating was substantial and increased with worsening POPC and PCPC scores. We also found a significant (P < .001) difference between the FSS-CNS scores between each of the PCPC ratings with increases in the FSS-CNS score for each higher PCPC rating.
  
  
  CONCLUSIONS
  The FSS and POPC/PCPC system are closely associated. Increases in FSS scores occur with each higher POPC and PCPC rating and with greater magnitudes of change as the dysfunction severity increases. However, the dispersion of the FSS scores indicated a lack of precision in the POPC/PCPC system when compared with the more objective and granular FSS. The relationship between the PCPC and the FSS-CNS paralleled the relationship between the FSS and POPC/PCPC system.
authors.affiliation: Department of Critical Care Medicine, Phoenix Children's Hospital, Phoenix, Arizona2Department of Child Health, University of Arizona College of Medicine-Phoenix.
authors.forename: Murray M
authors.initials: MM
authors.lastname: Pollack
authors.affiliation: Department of Pediatrics, University of Utah School of Medicine, Salt Lake City.
authors.forename: Richard
authors.initials: R
authors.lastname: Holubkov
authors.affiliation: Department of Pediatrics, University of Utah School of Medicine, Salt Lake City.
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Funai
authors.affiliation: Department of Pediatrics, University of Utah School of Medicine, Salt Lake City.
authors.forename: Amy
authors.initials: A
authors.lastname: Clark
authors.affiliation: Department of Pediatrics, University of Michigan, Ann Arbor.
authors.forename: Frank
authors.initials: F
authors.lastname: Moler
authors.affiliation: Department of Pediatrics, University of Michigan, Ann Arbor.
authors.forename: Thomas
authors.initials: T
authors.lastname: Shanley
authors.affiliation: Department of Pediatrics, Children's Hospital of Michigan, Detroit.
authors.forename: Kathy
authors.initials: K
authors.lastname: Meert
authors.affiliation: Department of Anesthesiology and Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, California.
authors.forename: Christopher J L
authors.initials: CJ
authors.lastname: Newth
authors.affiliation: Department of Critical Care Medicine, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.
authors.forename: Joseph
authors.initials: J
authors.lastname: Carcillo
authors.affiliation: Department of Pediatrics, Children's National Medical Center, Washington, DC.
authors.forename: John T
authors.initials: JT
authors.lastname: Berger
authors.affiliation: Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri10Department of Biochemistry, Washington University School of Medicine, St Louis, Missouri.
authors.forename: Allan
authors.initials: A
authors.lastname: Doctor
authors.affiliation: Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
authors.forename: Robert A
authors.initials: RA
authors.lastname: Berg
authors.affiliation: Department of Critical Care Medicine, Phoenix Children's Hospital, Phoenix, Arizona2Department of Child Health, University of Arizona College of Medicine-Phoenix.
authors.forename: Heidi
authors.initials: H
authors.lastname: Dalton
authors.affiliation: Department of Pediatrics, Children's National Medical Center, Washington, DC.
authors.forename: David L
authors.initials: DL
authors.lastname: Wessel
authors.affiliation: Department of Pediatrics, University of California, Los Angeles.
authors.forename: Rick E
authors.initials: RE
authors.lastname: Harrison
authors.affiliation: Department of Pediatrics, University of Utah School of Medicine, Salt Lake City.
authors.forename: J Michael
authors.initials: JM
authors.lastname: Dean
authors.affiliation: Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
authors.forename: Tammara L
authors.initials: TL
authors.lastname: Jenkins
mesh_terms: D000293:Adolescent; D002648:Child; D002657:Child Development; D002675:Child, Preschool; D003072:Cognition Disorders / Q000145:classification*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015278:Intensive Care Units, Pediatric; D007902:Length of Stay; D017063:Outcome Assessment, Health Care / Q000379:methods*; D010351:Patient Discharge; D010372:Pediatrics / Q000379:methods*; D011446:Prospective Studies; D011594:Psychometrics; D015203:Reproducibility of Results; D012720:Severity of Illness Index