title: Investigating the interaction of sunset yellow aggregates and 6-fluoro-2-naphthoic acid: increasing probe molecule complexity.
abstract: The interaction of small molecules with non-covalent assemblies is of wide interest. The use of a magnetically active reporter nucleus allows information to be obtained in the presence of spectral overlap or in cases of high dynamic range. In this paper, we explore the interaction of a larger probe molecule, 6-fluoro-2-naphthoic acid with assemblies of sunset yellow using (19)F chemical shifts and diffusion NMR methods. Comparing the observations with previous studies using fluorophenols, 6-fluoro-2-naphthoic acid prefers to associate as clusters at the ends of the sunset yellow stacks.
authors.affiliation: School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QJ, UK.
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Katz
authors.forename: Iain J
authors.initials: IJ
authors.lastname: Day
mesh_terms: D001391:Azo Compounds / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015335:Molecular Probes / Q000737:chemistry*; D009281:Naphthalenes / Q000737:chemistry*
chemical_list: D001391:Azo Compounds; D002264:Carboxylic Acids; D015335:Molecular Probes; D009281:Naphthalenes; C085312:1-naphthoic acid; C005842:6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt
keywords: 19F; NMR; aggregation; diffusion NMR; equilibrium; sunset yellow