title: Epidemiology of basal cell carcinoma in the United Kingdom: incidence, lifestyle factors, and comorbidities.
abstract: BACKGROUND
  Little is known about the epidemiology of basal cell carcinoma (BCC).
  
  
  METHODS
  Using the Clinical Practice Research Datalink, we calculated annual incidence rates. In a case-control analysis, we examined lifestyle factors and comorbidities.
  
  
  RESULTS
  Incidence rose significantly between 2000 and 2011. Basal cell carcinoma risk was increased in alcohol drinkers (slightly) and immunocompromised patients, but reduced in smokers and individuals with abnormal weight.
  
  
  CONCLUSIONS
  Basal cell carcinoma places a growing public health burden. Lifestyle factors do not play a major role in pathogenesis, but immunosuppression is important.
authors.affiliation: 1] Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacy and Epidemiology, Department of Pharmaceutical Sciences, University of Basel, Spitalstrasse 26, Basel CH-4031, Switzerland [2] Hospital Pharmacy, University Hospital Basel, Basel, Switzerland.
authors.forename: D
authors.initials: D
authors.lastname: Reinau
authors.affiliation: Department of Dermatology, University Hospital Basel, Basel, Switzerland.
authors.forename: C
authors.initials: C
authors.lastname: Surber
authors.affiliation: Boston Collaborative Drug Surveillance Program, Boston University School of Public Health, Lexington, MA, USA.
authors.forename: S S
authors.initials: SS
authors.lastname: Jick
authors.affiliation: 1] Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacy and Epidemiology, Department of Pharmaceutical Sciences, University of Basel, Spitalstrasse 26, Basel CH-4031, Switzerland [2] Hospital Pharmacy, University Hospital Basel, Basel, Switzerland [3] Boston Collaborative Drug Surveillance Program, Boston University School of Public Health, Lexington, MA, USA.
authors.forename: C R
authors.initials: CR
authors.lastname: Meier
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002280:Basal Cell Carcinoma / Q000453:epidemiology* / Q000473:pathology; D016022:Case-Control Studies; D015897:Comorbidity; D005260:Female; D006801:Humans; D015994:Incidence; D008019:Life Style; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012878:Skin Neoplasms / Q000453:epidemiology* / Q000473:pathology; D006113:United Kingdom / Q000453:epidemiology; D055815:Young Adult