title: Different risk factors of recurrent pulmonary tuberculosis between Tibetan and Han populations in Southwest China.
abstract: OBJECTIVE
  The geographical environment and living habits are different between Tibetan and Han populations. The present study aimed to investigate the risk factors of recurrent pulmonary tuberculosis (TB), and analyze the differences between the two populations.
  
  
  METHODS
  A total of 480 TB patients, including 80 Tibetan and 80 Han patients with recurrent pulmonary TB, and 320 patients without recurrent pulmonary TB, were included in present study. All patients with pulmonary TB were diagnosed between 2000 and 2001 and followed until December 2012. Multivariate logistic regression was used for the statistical analysis.
  
  
  RESULTS
  Among all patients, the independent risk factors associated with recurrent pulmonary TB were no use of directly observed therapy, short course (DOTS) (HR 5.867, 95% CI 2.557-13.461), diabetes (HR 3.288, 95% CI 1.301-8.312), smoking (HR 2.387, 95% CI 1.328-4.291) and malnutrition (HR 1.910, 95% CI 1.110-3.285). The independent risk factors of recurrent pulmonary TB for the Tibetan patients included no use of DOTS and malnutrition, while the independent risk factors for the Han patients were diabetes and smoking.
  
  
  CONCLUSIONS
  The risk factors of pulmonary TB recurrence were different between Tibetan and Han patients. To reduce the recurrent rate of pulmonary TB, especially for Tibetan populations, pursuing high-quality DOTS is essential.
authors.affiliation: Department of Respiratory Medicine, West China Hospital of Sichuan University and Division of Pulmonary Diseases, State Key Laboratory of Biotherapy of China, Chengdu, China. wenfuqiang.scu@gmail.com.
authors.forename: P-W
authors.initials: PW
authors.lastname: Tian
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
authors.forename: Y-C
authors.initials: YC
authors.lastname: Shen
authors.forename: L
authors.initials: L
authors.lastname: Chen
authors.forename: C
authors.initials: C
authors.lastname: Wan
authors.forename: Z-L
authors.initials: ZL
authors.lastname: Liao
authors.forename: F-Q
authors.initials: FQ
authors.lastname: Wen
mesh_terms: D000328:Adult; D044466:Asian People / Q000208:ethnology; D002681:China / Q000453:epidemiology; D003920:Diabetes Mellitus / Q000453:epidemiology; D023801:Directly Observed Therapy; D005260:Female; D006801:Humans; D008297:Male; D044342:Malnutrition / Q000453:epidemiology; D008875:Middle Aged; D012008:Recurrence; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology* / Q000208:ethnology*