title: A population of patient-specific adult acquired flatfoot deformity models before and after surgery.
abstract: Following IRB approval, a cohort of 3-D rigid-body computational models was created from submillimeter MRIs of clinically diagnosed Adult Acquired Flatfoot Deformity patients and employed to investigate postoperative foot/ankle function and surgical effect during single-leg stance. Models were constrained through physiologic joint contact, passive soft-tissue tension, active muscle force, full body weight, and without idealized joints. Models were validated against patient-matched controls using clinically utilized radiographic angle and distance measures and plantar force distributions in the medial forefoot, lateral forefoot, and hindfoot. Each model further predicted changes in strain for the spring ligament, deltoid ligament, and plantar fascia, as well as joint contact loads for three midfoot joints, the talonavicular, navicular-1st cuneiform, and calcaneocuboid. Radiographic agreement ranged across measures, with average absolute deviations of <5° and <4 mm indicating generally good agreement. Postoperative plantar force loading in patients and models was reduced for the medial forefoot and hindfoot concomitant with increases in the lateral forefoot. Model predicted reductions in medial soft-tissue strain and increases in lateral joint contact load were consistent with in vitro observations and elucidate the biomechanical mechanisms of repair. Thus, validated rigid-body models offer promise for the investigation of foot/ankle kinematics and biomechanical behaviors that are difficult to measure in vivo.
authors.affiliation: Orthopaedic Research Laboratory, Departments of Biomedical Engineering and Orthopaedic Surgery, Virginia Commonwealth University, Richmond, VA, USA.
authors.forename: E M
authors.initials: EM
authors.lastname: Spratley
authors.forename: E A
authors.initials: EA
authors.lastname: Matheis
authors.forename: C W
authors.initials: CW
authors.lastname: Hayes
authors.forename: R S
authors.initials: RS
authors.lastname: Adelaar
authors.forename: J S
authors.initials: JS
authors.lastname: Wayne
mesh_terms: D000328:Adult; D000368:Aged; D000842:Ankle; D005260:Female; D005413:Flatfoot / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D005528:Foot; D005531:Foot Deformities, Acquired / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D008954:Models, Biological; D011184:Postoperative Period; D057234:Preoperative Period; D011859:Radiography