title: New phenolic glycosides from Pilea cavaleriei.
abstract: Five new phenolic glycosides, 2-hydroxy-(2'E)-prenyl benzoate-2,4'-di-O-β-D-glucopyranoside (1), 2-hydroxy-(2'E)-prenyl benzoate-2-O-α-L-arabinopyranosyl-(1 → 6)-β-D-glucopyranoside (2), 4-methylphenol-1-O-α-L-rhamnopyranosyl-(1 → 6)-β-D-glucopyranoside (3), 4-methylphenol-1-O-α-L-arabinopyranosyl-(1 → 6)-β-D-glucopyranoside (4), and 3,5-dimethoxyphenol-1-O-β-D-apiofuranosyl-(1 → 2)-β-D-glucopyranoside (5), together with six known glycosides (6-11), were isolated from the n-BuOH fraction of the EtOH extract of Pilea cavaleriei Levl subsp. cavaleriei. Their structures were elucidated by extensive spectroscopic analysis, including 1D and 2D NMR spectroscopy as well as HR-ESI-MS, and chemical evidences. All these compounds were isolated from the genus Pilea for the first time.
authors.affiliation: a State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University , Beijing 100191 , China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhou
authors.forename: Heng-Chun
authors.initials: HC
authors.lastname: Ren
authors.forename: Ri-Dong
authors.initials: RD
authors.lastname: Qin
authors.forename: Qing-Ying
authors.initials: QY
authors.lastname: Zhang
authors.forename: Hong
authors.initials: H
authors.lastname: Liang
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism; D027003:Urticaceae / Q000737:chemistry*
chemical_list: D004365:Drugs, Chinese Herbal; D006027:Glycosides; D010636:Phenols
keywords: Pilea cavaleriei Levl subsp. cavaleriei; Urticaceae; phenolic glycosides