title: Organocatalytic enantioselective allylic alkylation of MBH carbonates with β-keto esters.
abstract: The highly stereoselective allylic alkylation of Morita-Baylis-Hillman carbonates with β-ketoesters catalysed by β-ICD is described. The corresponding products containing two adjacent quaternary and tertiary carbon centers were obtained in good yields with high diastereoselectivity (up to 10 : 1 dr) and enantioselectivity (up to 95% ee).
authors.affiliation: Department of Organic Chemistry, Faculty of Science, Charles University in Prague, Hlavova 2030, 128 43 Praha 2, Czech Republic. jxvesely@natur.cuni.cz.
authors.forename: M
authors.initials: M
authors.lastname: Kamlar
authors.forename: S
authors.initials: S
authors.lastname: Hybelbauerová
authors.forename: I
authors.initials: I
authors.lastname: Císařová
authors.forename: J
authors.initials: J
authors.lastname: Veselý