title: Diffuse Myocardial Uptake of (99m)Tc-HDP in Multiple Myeloma.
abstract: Soft tissue uptake is a rare finding in bone scintigraphy, with an incidence of 2%. Although the mechanism has not yet been fully clarified, several causes have been reported for this unusual uptake pattern. This paper presents a case of diffuse myocardial accumulation of technetium-99m hydroxymethylene diphosphonate ((99m)Tc-HDP) without either solid/visceral organ or soft tissue with multiple myeloma (MM) in skeletal scintigraphy. A 93-year-old man with hypertension and chronic heart failure for 14 years underwent bone scanning due to a 2-month history of back pain within a 1-year period of MM. Three hours later, (99m)Tc-HDP late static images showed diffuse myocardial radiotracer accumulation and there were no other sites of abnormal soft tissue or visceral uptake. Myocardial accumulation had disappeared on 24-h delayed static images. This accumulation was thought to be related with AL-type amyloidosis associated with MM.
authors.affiliation: Department of Nuclear Medicine, Ministry of Health Ankara Training and Research Hospital, Ulucanlar Street, 06340 Ankara, Turkey.
authors.forename: Koray
authors.initials: K
authors.lastname: Demirel
authors.affiliation: Department of Nuclear Medicine, Ministry of Health Ankara Training and Research Hospital, Ulucanlar Street, 06340 Ankara, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Sadic
authors.affiliation: Department of Nuclear Medicine, Ministry of Health Ankara Training and Research Hospital, Ulucanlar Street, 06340 Ankara, Turkey.
authors.forename: Meliha
authors.initials: M
authors.lastname: Korkmaz
authors.affiliation: Department of Nuclear Medicine, Ministry of Health Ankara Training and Research Hospital, Ulucanlar Street, 06340 Ankara, Turkey.
authors.forename: Aylin
authors.initials: A
authors.lastname: Comak
authors.affiliation: Department of Nuclear Medicine, Ministry of Health Ankara Training and Research Hospital, Ulucanlar Street, 06340 Ankara, Turkey.
authors.forename: Hasan Ikbal
authors.initials: HI
authors.lastname: Atilgan
authors.affiliation: Department of Nuclear Medicine, Ministry of Health Ankara Training and Research Hospital, Ulucanlar Street, 06340 Ankara, Turkey.
authors.forename: Gökhan
authors.initials: G
authors.lastname: Koca
keywords: Multiple myeloma; Myocardial uptake; Technetium-99m bone agents; Technetium-99m hydroxymethylene diphosphonate (99mTc-HDP)