title: CROI 2014: Advances in antiretroviral therapy.
abstract: The 2014 Conference on Retroviruses and Opportunistic Infections (CROI) highlighted important advances in antiretroviral therapy, with an emphasis on HIV eradication strategies. Follow-up information about the Mississippi baby who remains free of HIV infection off antiretroviral therapy was presented, and a second baby and 1 adult may also have been cured with very early initiation of antiretroviral therapy. The HIV care cascade was again a major focus of the conference. Investigators from around the world presented data on the implementation, and limitations, of the care cascade paradigm. Scale-up of antiretroviral therapy continues and a number of presentations featured optimal ways to measure the impact of these efforts by applying lessons from implementation science and health care economics. Encouraging results from expanded prevention of mother-to-child transmission programs, especially Option B+, were highlighted. Extensive data on transmitted (primary) drug resistance in the United States and Europe were presented.
authors.affiliation: University of Texas Health Science Center, San Antonio, TX, USA.
authors.forename: Barbara S
authors.initials: BS
authors.lastname: Taylor
authors.affiliation: Columbia University College of Physicians and Surgeons, New York, NY, USA.
authors.forename: Noga
authors.initials: N
authors.lastname: Shalev
authors.affiliation: Weill Cornell Medical College, New York, NY, USA.
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Wilkin
mesh_terms: D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods*; D018890:Chemoprevention / Q000379:methods; D018562:Disease Transmission, Infectious / Q000517:prevention & control; D014943:Global Health; D015658:HIV Infections / Q000188:drug therapy* / Q000517:prevention & control; D006801:Humans; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D044966:Anti-Retroviral Agents