title: Polybrominated diphenyl ethers, 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153), and p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) concentrations in sera collected in 2009 from Texas children.
abstract: Polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs) and p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) have been measured in surplus serum collected in 2009 from a convenience sample of 300 Texas children (boys and girls) in the birth to 13 years of age range. Serum concentrations of traditional persistent organic pollutants such as 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) and p,p'-DDE did not change consistently with age. By contrast, serum concentrations of tetra-, penta-, and hexa-BDEs were lowest in the youngest children (birth to two year old) and increased 3.0 to 7.9 times, depending on the analyte, for children in the >4 to 6 years of age group. From the apex concentration to the 10 to 13 years of age group, concentrations decreased significantly except for 2,2',4,4',5,5'-hexabromodiphenyl ether (PBDE-153), which also had a longer apex concentration of >4 to 8 years of age. This concentration trend for PBDE-153 is most likely due to a longer half-life of PBDE-153 than of other PBDE congeners. The observed PBDEs concentration patterns by age may be related, at least in part, to ingestion of residential dust containing PBDEs through hand-to-mouth behavior among toddlers, preschoolers, and kindergarteners. Further studies to characterize young children's exposure to PBDEs are warranted and, in particular, to determine the lifestyle factors that may contribute to such exposures.
authors.affiliation: National Center for Environmental Health, Centers for Disease Control and Prevention , 4770 Buford Highway, Atlanta, Georgia 30341, United States.
authors.forename: Andreas
authors.initials: A
authors.lastname: Sjödin
authors.forename: Arnold
authors.initials: A
authors.lastname: Schecter
authors.forename: Richard
authors.initials: R
authors.lastname: Jones
authors.forename: Lee-Yang
authors.initials: LY
authors.lastname: Wong
authors.forename: Justin A
authors.initials: JA
authors.lastname: Colacino
authors.forename: Noor
authors.initials: N
authors.lastname: Malik-Bass
authors.forename: Yalin
authors.initials: Y
authors.lastname: Zhang
authors.forename: Sarah
authors.initials: S
authors.lastname: Anderson
authors.forename: Cheryl
authors.initials: C
authors.lastname: McClure
authors.forename: Wayman
authors.initials: W
authors.lastname: Turner
authors.forename: Antonia M
authors.initials: AM
authors.lastname: Calafat
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D016001:Confidence Intervals; D003633:Dichlorodiphenyl Dichloroethylene / Q000097:blood*; D004784:Environmental Monitoring; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D057230:Limit of Detection; D008297:Male; D011078:Polychlorinated Biphenyls / Q000097:blood*; D013781:Texas
chemical_list: D003633:Dichlorodiphenyl Dichloroethylene; D011078:Polychlorinated Biphenyls; C014024:2,4,5,2',4',5'-hexachlorobiphenyl