title: Actinic prurigo.
abstract: Actinic prurigo is a chronic photodermatosis with onset in childhood or before 20 years of age. It is most prevalent in Amerindians and Latin American mestizos, although it has been reported worldwide. Patients present with photodistributed, erythematous excoriated papules, cheilitis, and conjunctivitis. There is strong association with human leukocyte antigen DR4, especially the DRB1*0407 subtype. Treatment consists of photoprotection and the use of thalidomide.
authors.affiliation: Photodermatology Unit, Centro Dermatológico Federico Lleras Acosta, Avda. 1 No. 13A-61, Bogotá, Colombia. Electronic address: marvalbuen@yahoo.com.
authors.forename: Martha C
authors.initials: MC
authors.lastname: Valbuena
authors.affiliation: Research and Education Department, Research and Education Office, Centro Dermatológico Federico Lleras Acosta, Avda. 1 No. 13A-61, Bogotá, Colombia.
authors.forename: Sandra
authors.initials: S
authors.lastname: Muvdi
authors.affiliation: Department of Dermatology, Henry Ford Health System, Henry Ford Medical Center - New Center One, 3031 West Grand Boulevard, Detroit, MI 48202, USA.
authors.forename: Henry W
authors.initials: HW
authors.lastname: Lim
mesh_terms: D001706:Biopsy; D014943:Global Health; D006801:Humans; D010787:Photosensitivity Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D015995:Prevalence; D012867:Skin / Q000473:pathology / Q000528:radiation effects; D012873:Skin Diseases, Genetic / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D014466:Ultraviolet Rays / Q000009:adverse effects*
keywords: Actinic prurigo; Human leukocyte antigen; Polymorphic light eruption; Thalidomide