title: Voltage-gated potassium channel antibody-associated limbic encephalitis.
abstract: We are emphasising the importance of considering a rare diagnosis, voltage-gated Potassium channel antibody-associated limbic encephalitis, in an 80-year-old gentleman who presented with memory impairment, seizure and hyponatraemia. He was found to have high titre of voltage-gated potassium channel antibodies in his serum. He was given high-dose steroids and he responded biochemically and clinically with marked improvement in symptomatology.
authors.affiliation: Medicine, Yeovil District Hospital NHS Foundation Trust, Yeovil District Hospital Higher Kingston, Yeovil, Somerset BA21 4AT, UK.
authors.forename: Atif
authors.initials: A
authors.lastname: Saleem
authors.affiliation: Medicine (Care of the Elderly), Yeovil District Hospital NHS Foundation Trust, Yeovil, Somerset, UK.
authors.forename: Rani
authors.initials: R
authors.lastname: Sophia
mesh_terms: D000369:Aged, 80 and over; D000906:Antibodies / Q000097:blood*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007010:Hyponatremia / Q000209:etiology; D020363:Limbic Encephalitis / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology*; D008297:Male; D008569:Memory Disorders / Q000209:etiology; D024642:Potassium Channels, Voltage-Gated / Q000276:immunology*; D012640:Seizures / Q000209:etiology; D013256:Steroids / Q000627:therapeutic use
chemical_list: D000906:Antibodies; D024642:Potassium Channels, Voltage-Gated; D013256:Steroids
keywords: VGKC antibody-associated encephalitis; encephalitis; limbic encephalitis; older people