title: Ehealth monitoring in irritable bowel syndrome patients treated with low fermentable oligo-, di-, mono-saccharides and polyols diet.
abstract: In the present study we report on changes in irritable bowel syndrome-severity scoring system (IBS-SSS) and irritable bowel syndrome-quality of life (IBS-QoL) in 19 IBS patients, aged 18 to 74 years (F/M: 14/5), during 12 wk registering their symptoms on the web-application (www.ibs.constant-care.dk). During a control period of the first 6-wk patients were asked to register their IBS-SSS and IBS-QoL on the web-application weekly without receiving any intervention. Thereafter, low fermentable oligo-, di-, mono-saccharides and polyols (FODMAP) diet (LFD) was introduced for the next 6 wk while continuing the registration. Though a small sample size a significant improvement in disease activity (IBS-SSS) was observed during both the control period, median: 278 (range: 122-377), P = 0.02, and subsequently during the LFD period, median: 151 (range: 29-334), P < 0.01. The IBS-QoL solely changed significantly during the LFD period, median: 67 (37-120), P < 0.01. The significant reduction in disease activity during the control period shows a positive effect of the web-application on IBS symptoms when presented as a "traffic light". However adding the diet reduced IBS-SSS to < 150, inactive to mild symptoms. In the future results from larger scale trials are awaited.
authors.affiliation: Natalia Pedersen, Johan Burisch, Lisbeth Jensen, Pia Munkholm, Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen 2730, Denmark.
authors.forename: Natalia
authors.initials: N
authors.lastname: Pedersen
authors.affiliation: Natalia Pedersen, Johan Burisch, Lisbeth Jensen, Pia Munkholm, Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen 2730, Denmark.
authors.forename: Zsuzsanna
authors.initials: Z
authors.lastname: Vegh
authors.affiliation: Natalia Pedersen, Johan Burisch, Lisbeth Jensen, Pia Munkholm, Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen 2730, Denmark.
authors.forename: Johan
authors.initials: J
authors.lastname: Burisch
authors.affiliation: Natalia Pedersen, Johan Burisch, Lisbeth Jensen, Pia Munkholm, Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen 2730, Denmark.
authors.forename: Lisbeth
authors.initials: L
authors.lastname: Jensen
authors.affiliation: Natalia Pedersen, Johan Burisch, Lisbeth Jensen, Pia Munkholm, Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen 2730, Denmark.
authors.forename: Dorit Vedel
authors.initials: DV
authors.lastname: Ankersen
authors.affiliation: Natalia Pedersen, Johan Burisch, Lisbeth Jensen, Pia Munkholm, Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen 2730, Denmark.
authors.forename: Maria
authors.initials: M
authors.lastname: Felding
authors.affiliation: Natalia Pedersen, Johan Burisch, Lisbeth Jensen, Pia Munkholm, Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen 2730, Denmark.
authors.forename: Nynne Nyboe
authors.initials: NN
authors.lastname: Andersen
authors.affiliation: Natalia Pedersen, Johan Burisch, Lisbeth Jensen, Pia Munkholm, Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen 2730, Denmark.
authors.forename: Pia
authors.initials: P
authors.lastname: Munkholm
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004032:Diet; D004187:Disaccharides / Q000008:administration & dosage; D005260:Female; D005285:Fermentation; D006801:Humans; D020407:Internet; D043183:Irritable Bowel Syndrome / Q000178:diet therapy* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009005:Monosaccharides / Q000008:administration & dosage; D009844:Oligosaccharides / Q000008:administration & dosage*; D011108:Polymers / Q000008:administration & dosage; D011788:Quality of Life; D012074:Remission Induction; D017216:Telemedicine; D014584:User-Computer Interface; D055815:Young Adult
chemical_list: D004187:Disaccharides; D009005:Monosaccharides; D009844:Oligosaccharides; D011108:Polymers; C024617:polyol
keywords: Disease activity; Disease-specific quality of life; Irritable bowel syndrome; Low fermentable oligo-, di-, mono-saccharides and polyols diet; Self-management