title: Electroreductive coupling of optically active α,β-unsaturated carbonyl compounds with diaryl ketones: asymmetric synthesis of 4,5,5-trisubstituted γ-butyrolactones.
abstract: The electroreductive coupling of optically active N-E-crotonoyl- and N-cinnamoylimidazolidin-2-ones and oxazolidin-2-ones with diaryl ketones in the presence of chlorotrimethylsilane gave adducts with high diastereoselectivity. The adducts were readily transformed to optically active 4,5,5-trisubstituted γ-butyrolactones by treatment with TBAF.
authors.affiliation: Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University , 4-101, Koyama-cho Minami, Tottori 680-8552, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Kise
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Hamada
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Sakurai