title: Diastereoselective total synthesis of salvileucalin C.
abstract: A concise and efficient approach for the diastereoselective total synthesis of salvileucalin C, as well as their biosynthetically related diterpenoids salvileucalin D, salvipuberulin, isosalvipuberulin, and dugesin B, has been reported for the first time. The key features of the strategy are based on a Beckwith-Dowd ring expansion, a tandem diastereoselective Stille coupling/debromination/desilylation/lactonization reaction, and a photoinduced electrocyclic ring contraction.
authors.affiliation: Department of Chemistry, Zhejiang University , 148 Tianmushan Road, Hangzhou 310028, P. R. China.
authors.forename: Chenchen
authors.initials: C
authors.lastname: Fu
authors.forename: Yuanbao
authors.initials: Y
authors.lastname: Zhang
authors.forename: Jun
authors.initials: J
authors.lastname: Xuan
authors.forename: Chenlong
authors.initials: C
authors.lastname: Zhu
authors.forename: Bingnan
authors.initials: B
authors.lastname: Wang
authors.forename: Hanfeng
authors.initials: H
authors.lastname: Ding
mesh_terms: D004224:Diterpenes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D027544:Salvia / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D004224:Diterpenes; C000590292:salvileucalin C