title: Rapid brain death caused by a cerebellar abscess with Fusobacterium nucleatum in a young man with drug abuse: a case report.
abstract: BACKGROUND
  Fusobacterium nucleatum is a strict anaerobic microorganism that causes disease entities such as periodontal and soft tissue abscesses, pulmonary and intraabdominal infections and very rarely intracerebral infections.
  
  
  METHODS
  Here, we report the rare case of a previously healthy 25-year-old German man with a cerebellar abscess caused by Fusobacterium nucleatum that resulted in rapid brain death. Toxicological screening showed positivity for amphetamines and cannabis. The diagnosis was obtained by polymerase chain reaction amplification of bacterial deoxyribonucleic acid in cerebrospinal fluid.
  
  
  CONCLUSIONS
  In drug users clinicians should think about rare causes of brain abscesses/meningitis. Early diagnosis is necessary and justifies the use of molecular techniques.
authors.affiliation: Institute of Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn, Sigmund-Freud-Str, 25, D-53127 Bonn, Germany. hischebeth@microbiology-bonn.de.
authors.forename: Gunnar T R
authors.initials: GT
authors.lastname: Hischebeth
authors.forename: Vera C
authors.initials: VC
authors.lastname: Keil
authors.forename: Katrin
authors.initials: K
authors.lastname: Gentil
authors.forename: Azize
authors.initials: A
authors.lastname: Boström
authors.forename: Klaus
authors.initials: K
authors.lastname: Kuchelmeister
authors.forename: Isabelle
authors.initials: I
authors.lastname: Bekeredjian-Ding
mesh_terms: D000328:Adult; D001922:Brain Abscess / Q000150:complications / Q000382:microbiology*; D001926:Brain Death; D005674:Fusobacterium Infections / Q000150:complications* / Q000382:microbiology; D016967:Fusobacterium nucleatum / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D019966:Substance-Related Disorders / Q000150:complications*