title: Brain substrates of recovery from misleading influence.
abstract: Humans are strongly influenced by their environment, a dependence that can lead to errors in judgment. Although a rich literature describes how people are influenced by others, little is known regarding the factors that predict subsequent rectification of misleading influence. Using a mediation model in combination with brain imaging, we propose a model for the correction of misinformation. Specifically, our data suggest that amygdala modulation of hippocampal mnemonic representations, during the time of misleading social influence, is associated with reduced subsequent anterior-lateral prefrontal cortex activity that reflects correction. These findings illuminate the process by which erroneous beliefs are, or fail to be, rectified and highlight how past influence constrains subsequent correction.
authors.affiliation: Department of Neurobiology, Weizmann Institute of Science, Israel, Rehovot 7610001, micah.edelson@weizmann.ac.il.
authors.forename: Micah G
authors.initials: MG
authors.lastname: Edelson
authors.affiliation: Department of Neurobiology, Weizmann Institute of Science, Israel, Rehovot 7610001, Center for Neural Science, New York University, New York, New York 10003.
authors.forename: Yadin
authors.initials: Y
authors.lastname: Dudai
authors.affiliation: Wellcome Trust Center for Neuroimaging, Institute of Neurology, University College London, London, United Kingdom, WC1N 3BG.
authors.forename: Raymond J
authors.initials: RJ
authors.lastname: Dolan
authors.affiliation: Affective Brain Lab, Department of Cognitive Perceptual and Brain Science, University College London, London, United Kingdom, WC1E 6BT, and.
authors.forename: Tali
authors.initials: T
authors.lastname: Sharot
mesh_terms: D000328:Adult; D001921:Brain / Q000098:blood supply / Q000502:physiology*; D001931:Brain Mapping; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007600:Judgment / Q000502:physiology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008568:Memory / Q000502:physiology*; D008960:Models, Psychological; D009434:Neural Pathways / Q000098:blood supply / Q000502:physiology; D010100:Oxygen / Q000097:blood; D010775:Photic Stimulation; D011930:Reaction Time / Q000502:physiology; D012919:Social Behavior
chemical_list: D010100:Oxygen
keywords: brain; fMRI; memory; recovery; social