title: Adherence to clinical care guidelines for cystic fibrosis-related diabetes in 659 German/Austrian patients.
abstract: BACKGROUND
  In Germany/Austria, data on medical care for cystic fibrosis-related diabetes (CFRD) is limited.
  
  
  METHODS
  Anonymized data from 659 CFRD patients were analyzed and compared to the latest ADA/CFF guidelines.
  
  
  RESULTS
  Specialized diabetes clinics were attended less frequently than recommended (3.1 vs. 4.0 times yearly). 7.9% of patients had a complete profile of examinations: diabetes education (44.9%), HbA1c (88.8%), blood pressure (79.5%), BMI (86.5%), lipid status (37.5%), retinopathy (29.9%), microalbuminuria (33.2%), and self-monitoring of blood glucose (71.6%). HbA1c and blood pressure were measured less frequently than recommended (2.3 and 2.0 vs. 4.0 times yearly). Overall, guidelines were followed more frequently in children than adults. Contrary to recommendations, not all patients were treated with insulin (77.2 vs. 100.0%). Insulin therapy was initiated earlier in children than adults, but there was still a substantial delay (0.9 vs. 2.7years after diagnosis, p<0.001).
  
  
  CONCLUSIONS
  In CFRD patients studied, adherence to care guidelines was suboptimal.
authors.affiliation: Institute of Epidemiology and Medical Biometry, ZIBMT, University of Ulm, Albert-Einstein-Allee 41, D-89081 Ulm, Germany. Electronic address: nicole.scheuing@uni-ulm.de.
authors.forename: Nicole
authors.initials: N
authors.lastname: Scheuing
authors.affiliation: Department of Pediatrics and Adolescent Medicine, Medical University Vienna, Währinger Gürtel 18-20, A-1090 Vienna, Austria.
authors.forename: Gabriele
authors.initials: G
authors.lastname: Berger
authors.affiliation: Department of Internal Medicine I, Division of Endocrinology & Metabolism, Goethe University Hospital, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany.
authors.forename: Dominik
authors.initials: D
authors.lastname: Bergis
authors.affiliation: Pediatric Endocrinology Division, Children's Hospital, University of Bonn, Adenauerallee 119, D-53113 Bonn, Germany.
authors.forename: Bettina
authors.initials: B
authors.lastname: Gohlke
authors.affiliation: Department of Pediatrics II, University Children's Hospital Essen, Hufelandstraße 55, D-45147 Essen, Germany.
authors.forename: Katja
authors.initials: K
authors.lastname: Konrad
authors.affiliation: Department of Internal Medicine II, Division of Endocrinology and Diabetology, University Hospital of Freiburg, Hugstetter Straße 49, D-79106 Freiburg, Germany.
authors.forename: Katharina
authors.initials: K
authors.lastname: Laubner
authors.affiliation: Department of Pediatrics, University of Bochum, Alexandrinenstraße 5, D-44791 Bochum, Germany.
authors.forename: Eggert
authors.initials: E
authors.lastname: Lilienthal
authors.affiliation: Department of Pediatrics I, Medical University of Innsbruck, Christoph Probst Platz 1, A-6020 Innsbruck, Austria.
authors.forename: Christine
authors.initials: C
authors.lastname: Moser
authors.affiliation: 3rd Medical Department, Hospital Hietzing, Wolkersbergenstraße 1, A-1130 Vienna, Austria.
authors.forename: Ingrid
authors.initials: I
authors.lastname: Schütz-Fuhrmann
authors.affiliation: Department of Pediatrics, Hannover Medical School, Carl-Neuberg-Straße 1, D-30625 Hannover, Germany.
authors.forename: Angelika
authors.initials: A
authors.lastname: Thon
authors.affiliation: Institute of Epidemiology and Medical Biometry, ZIBMT, University of Ulm, Albert-Einstein-Allee 41, D-89081 Ulm, Germany.
authors.forename: Reinhard W
authors.initials: RW
authors.lastname: Holl
mesh_terms: D000293:Adolescent; D000328:Adult; D001317:Austria; D002648:Child; D003550:Cystic Fibrosis / Q000150:complications* / Q000628:therapy*; D048909:Diabetes Complications / Q000209:etiology / Q000628:therapy*; D005260:Female; D005858:Germany; D006442:Glycated Hemoglobin; D019983:Guideline Adherence; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D008297:Male; D015596:Nutrition Assessment; D017410:Practice Guidelines as Topic; D012042:Registries; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents
keywords: Anti-hyperglycemic therapy; Cystic fibrosis-related diabetes; Guideline recommendations; Insulin treatment; Medical care; Nutritional status