title: Is there more to subjective cognitive impairment than meets the eye? A perspective.
abstract: Multi-disciplinary research has revealed evidence of significant abnormality in a much wider range and level of information processing than that currently definitive for amnestic mild cognitive impairment (MCI). This raises the possibility that the contemporary approach to MCI is inappropriately delimited, and the true nature and extent of brain dysfunction and thus disease burden, underestimated. It follows therefore that the closely related concept of subjective cognitive impairment (SCI) may be similarly constrained. Although research into the wider range of potential brain dysfunction in MCI and SCI is in its infancy, as yet precluding systematic reviews, we present here findings to prompt debate about SCI with respect to its clinical assessment and its personal and societal burden.
authors.affiliation: College of Human and Health Sciences, Department of Psychology, Swansea University, Swansea, Wales, UK.
authors.forename: Andrea
authors.initials: A
authors.lastname: Tales
authors.affiliation: Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
authors.forename: Gordon K
authors.initials: GK
authors.lastname: Wilcock
authors.affiliation: College of Human and Health Sciences, OPAN, Swansea University, Swansea, Wales, UK.
authors.forename: Judith E
authors.initials: JE
authors.lastname: Phillips
authors.affiliation: School of Medicine, Cardiff University, University Hospital Llandough, Wales, UK.
authors.forename: Antony
authors.initials: A
authors.lastname: Bayer
mesh_terms: D003072:Cognition Disorders / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D006801:Humans; D008569:Memory Disorders / Q000523:psychology; D009483:Neuropsychological Tests
keywords: Mild cognitive impairment; subjective cognitive impairment