title: [Clinical and morphological features of papillary thyroid cancer in children and adolescents in the Republic of Belarus: analysis of 936 post-Chernobyl carcinomas].
abstract: There is presented clinical and morphological characteristics of post-Chernobyl papillary thyroid cancer in 936 children and adolescents. In general, carcinoma of these patients featured by locally advanced growth - 57.4% (387 of 674 patients with this sign could be assessed), metastases in regional lymph nodes - 73,7% (N1b in 40.7%) and internal organs - 11.1%. The mean duration of follow-up was 12,4 +/- 3,5 years (range 4.3 to 19.6 years) including children 14,6 +/- 2,7 years (range 8.8 to 19.6 years) and adolescents - 10,1 +/- 3,1 years (range 4.3 to 18.8 years). Overall survival for the 20-year period was 96,6% +/- 1,2%. The causes of death were suicide (7), injuries and accidents (5), secondary malignancies (1), somatic diseases (2). Only in two patients the death was related to the main disease - lung metastases. Free-recurrence survival for the cohort of post-Chernobyl carcinomas was 92,7% +/- 1,0%.
authors.forename: M V
authors.initials: MV
authors.lastname: Fridman
authors.forename: S V
authors.initials: SV
authors.lastname: Man'kovskaia
authors.forename: O V
authors.initials: OV
authors.lastname: Kras'ko
authors.forename: Iu E
authors.initials: IuE
authors.lastname: Demidchik
mesh_terms: D000293:Adolescent; D002277:Carcinoma / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology*; D002291:Carcinoma, Papillary; D002423:Cause of Death; D047852:Chernobyl Nuclear Accident; D002648:Child; D002675:Child, Preschool; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D002094:Republic of Belarus / Q000453:epidemiology; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology*; D055815:Young Adult