title: The optical, photothermal, and facile surface chemical properties of gold and silver nanoparticles in biodiagnostics, therapy, and drug delivery.
abstract: Nanotechnology is a rapidly growing area of research in part due to its integration into many biomedical applications. Within nanotechnology, gold and silver nanostructures are some of the most heavily utilized nanomaterial due to their unique optical, photothermal, and facile surface chemical properties. In this review, common colloid synthesis methods and biofunctionalization strategies of gold and silver nanostructures are highlighted. Their unique properties are also discussed in terms of their use in biodiagnostic, imaging, therapeutic, and drug delivery applications. Furthermore, relevant clinical applications utilizing gold and silver nanostructures are also presented. We also provide a table with reviews covering related topics.
authors.affiliation: Laser Dynamics Laboratory, Department of Chemistry and Biochemistry, Georgia Institute of Technology, 901 Atlantic Dr. NW, Atlanta, GA, 30332-0400, USA.
authors.forename: Lauren A
authors.initials: LA
authors.lastname: Austin
authors.forename: Megan A
authors.initials: MA
authors.lastname: Mackey
authors.forename: Erik C
authors.initials: EC
authors.lastname: Dreaden
authors.forename: Mostafa A
authors.initials: MA
authors.lastname: El-Sayed
mesh_terms: D000818:Animals; D003952:Diagnostic Imaging / Q000379:methods; D016503:Drug Delivery Systems; D006046:Gold / Q000737:chemistry*; D006801:Humans; D053768:Metal Nanoparticles; D036103:Nanotechnology / Q000379:methods; D012834:Silver / Q000737:chemistry*
chemical_list: D012834:Silver; D006046:Gold