title: Percutaneous Nephrolithotomy in Autosomal Dominant Polycystic Kidney Disease: Is it Different from Percutaneous Nephrolithotomy in Normal Kidney?
abstract: OBJECTIVE
  Nephrolithiasis has been reported in 20-28% of patients, of whom 50% are symptomatic for stone disease and 20% require definite urologic intervention. The management of nephrolithiasis includes oral alkali dissolution therapy, extracorporeal shock wave lithotripsy and surgical treatment. In such patients, percutaneous nephrolithotomy (PNL) as a method of stone treatment has been reported in few cases with limited experience. The aim of this study is to present our experience of PNL in autosomal dominant polycystic kidney disease (ADPKD) and assessing the outcome results.
  
  
  METHODS
  From 2002 to 2011, 22 patients (26 renal units) suffering from ADPKD with stone were managed by PNL. Demographic characteristics, operative parameters and postoperative complications were recorded and analysed.
  
  
  RESULTS
  The overall success rate of PNL was 82.1% and PNL with extracorporeal shock wave lithotripsy for clinically significant residual fragments was 92.85% respectively. The hematuria required blood transfusion (n = 9), postoperative fever due to cyst infection (n = 4) and paralytic ileus (n = 3) were recorded.
  
  
  CONCLUSIONS
  The PNL in ADPKD PNL is safe and effective but have more postoperative complications such as bleeding requiring transfusions, fever due to cyst infection and paralytic ileus.
authors.affiliation: Department of Urology, King George Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Vishwajeet
authors.initials: V
authors.lastname: Singh
authors.affiliation: Department of Urology, King George Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Rahul Janak
authors.initials: RJ
authors.lastname: Sinha
authors.affiliation: Department of Urology, King George Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Dheeraj Kumar
authors.initials: DK
authors.lastname: Gupta
keywords: Autosomal dominant polycystic kidney disease; Nephrolithiasis; Percutaneous nephrolithotomy