title: Genetic characterization of acquired aplastic anemia by targeted sequencing.
authors.affiliation: Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Germany heuser.michael@mh-hannover.de.
authors.forename: Michael
authors.initials: M
authors.lastname: Heuser
authors.affiliation: Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Germany.
authors.forename: Carola
authors.initials: C
authors.lastname: Schlarmann
authors.affiliation: Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Germany.
authors.forename: Vera
authors.initials: V
authors.lastname: Dobbernack
authors.affiliation: Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Germany.
authors.forename: Victoria
authors.initials: V
authors.lastname: Panagiota
authors.affiliation: Clinical Research Group, Department of Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Germany.
authors.forename: Lutz
authors.initials: L
authors.lastname: Wiehlmann
authors.affiliation: Institute of Medical Informatics, Münster University, Germany.
authors.forename: Carolin
authors.initials: C
authors.lastname: Walter
authors.affiliation: Department of Oncology, Hematology and Stem Cell Transplantation, RWTH Medical School, Aachen, Germany.
authors.forename: Fabian
authors.initials: F
authors.lastname: Beier
authors.affiliation: Department of Oncology, Hematology and Stem Cell Transplantation, RWTH Medical School, Aachen, Germany.
authors.forename: Patrick
authors.initials: P
authors.lastname: Ziegler
authors.affiliation: Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Germany.
authors.forename: Haiyang
authors.initials: H
authors.lastname: Yun
authors.affiliation: Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Germany.
authors.forename: Sofia
authors.initials: S
authors.lastname: Kade
authors.affiliation: Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Germany.
authors.forename: Aylin
authors.initials: A
authors.lastname: Kirchner
authors.affiliation: Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Germany Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, China.
authors.forename: Liu
authors.initials: L
authors.lastname: Huang
authors.affiliation: Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Koenecke
authors.affiliation: Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Eder
authors.affiliation: Department of Oncology, Hematology and Stem Cell Transplantation, RWTH Medical School, Aachen, Germany.
authors.forename: Tim H
authors.initials: TH
authors.lastname: Brümmendorf
authors.affiliation: Institute of Medical Informatics, Münster University, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Dugas
authors.affiliation: Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Germany.
authors.forename: Arnold
authors.initials: A
authors.lastname: Ganser
authors.affiliation: Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Germany.
authors.forename: Felicitas
authors.initials: F
authors.lastname: Thol
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000741:Anemia, Aplastic / Q000150:complications / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002352:Carrier Proteins / Q000235:genetics; D018797:Cell Cycle Proteins / Q000235:genetics; D002648:Child; D004268:DNA-Binding Proteins / Q000235:genetics; D049308:Dioxygenases; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009154:Mutation; D009190:Myelodysplastic Syndromes / Q000188:drug therapy / Q000209:etiology / Q000235:genetics* / Q000473:pathology; D009419:Nerve Tissue Proteins / Q000235:genetics; D009687:Nuclear Proteins / Q000235:genetics; D011518:Proto-Oncogene Proteins / Q000235:genetics; D012097:Repressor Proteins / Q000235:genetics; D017422:Sequence Analysis, DNA; D012720:Severity of Illness Index; D016615:Telomere; D059505:Telomere Homeostasis; D015534:Trans-Activators / Q000235:genetics
chemical_list: C473949:ASXL1 protein, human; D000970:Antineoplastic Agents; D002352:Carrier Proteins; D018797:Cell Cycle Proteins; D004268:DNA-Binding Proteins; C064352:MYBL2 protein, human; D009419:Nerve Tissue Proteins; D009687:Nuclear Proteins; D011518:Proto-Oncogene Proteins; D012097:Repressor Proteins; C425066:SETBP1 protein, human; C492289:SLIT1 protein, human; D015534:Trans-Activators; D049308:Dioxygenases; C541081:TET2 protein, human
keywords: MDS-related mutations; aplastic anemia