title: Mediator redefines itself.
abstract: Mediator is a large and structurally dynamic protein complex that is globally required for eukaryotic transcription by RNA polymerase II. In a recent paper published in Cell Research, Wang et al. report for the first time the location of distinct subunits and redefine domains in the S. cerevisiae Mediator complex.
authors.affiliation: Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80303, USA.
authors.forename: Nicholas C
authors.initials: NC
authors.lastname: Sennett
authors.affiliation: Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80303, USA.
authors.forename: Dylan J
authors.initials: DJ
authors.lastname: Taatjes
mesh_terms: D056892:Mediator Complex / Q000648:ultrastructure*; D021122:Protein Subunits / Q000378:metabolism*
chemical_list: D056892:Mediator Complex; D021122:Protein Subunits