title: Association between oxidative stress and nutritional status in the elderly.
abstract: Ageing is a dynamic and progressive process that is characterized by the occurrence of morphological, biochemical, functional and psychological changes in the organism. The aim of the present article is to provide updated concepts on oxidative stress, covering its importance in aging, as well as nutritional status and supplementation with antioxidants (substances that prevent or attenuate oxidation of oxidizable substrates, such as lipids, proteins, carbohydrates and deoxyribonucleic acid) in the geriatric population. Evidence suggests that there is an inverse relationship between oxidative stress and nutritional status in elderly individuals. Although an increase in oxidative stress in chronic diseases associated with aging has been proven, such as Parkinson's disease and Alzheimer's disease, up to now there has been no consistent clinical evidence proving the efficiency of supplementation with antioxidants against oxidative stress. In this context, supplementation is not recommended. On the other hand, the elderly should be encouraged to eat antioxidant foods, such as fruits and vegetables. Maintaining a normal weight (body mass index between 23 and 28 Kg/m(2)) should also be stimulated.
authors.affiliation: Master?s degree and Doctorate student, Department of Clinical Medicine, Botucatu School of Medicine, Universidade Estadual Paulista, Botucatu, SP, Brazil.
authors.forename: Priscila Lucelia
authors.initials: PL
authors.lastname: Moreira
authors.affiliation: Professor and Doctor, Department of Clinical Medicine, Botucatu School of Medicine, Universidade Estadual Paulista, Botucatu, SP, Brazil.
authors.forename: Paulo Jose Fortes
authors.initials: PJ
authors.lastname: Villas Boas
authors.affiliation: Physician and Assistant Professor, Department of Clinical Medicine, Botucatu School of Medicine, Universidade Estadual Paulista, Botucatu, SP, Brazil.
authors.forename: Ana Lucia Anjos
authors.initials: AL
authors.lastname: Ferreira
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology*; D000975:Antioxidants / Q000502:physiology; D001835:Body Weight / Q000502:physiology; D019587:Dietary Supplements / Q000009:adverse effects; D005638:Fruit; D006801:Humans; D009752:Nutritional Status / Q000502:physiology*; D018384:Oxidative Stress / Q000502:physiology*; D014675:Vegetables
chemical_list: D000975:Antioxidants