title: Tuberculosis in HIV patient.
abstract: BACKGROUND
  Strict monitoring ofanti tuberculosis therapy and antiretroviral therapyis crucial for proper management of TB/HIV co-infected patients.
  
  
  METHODS
  Between December 2006 and December 2008 a prospective observational study was conducted among 135 TB/HIV co-infected patients visiting antiretroviral therapy in Seti Zonal Hospital, Dhangadi. The diagnosed TB patients were subjected to ATT through directly observed treatment short-course (DOTS) and its response was evaluated as per WHO guidelines.
  
  
  RESULTS
  Among 135 studied subjects, 97 (71.9%) were males and over 119 (88 %) of the patients were in the age group 21 to 50. Of the total TB cases 92 (68.1%) presented pulmonary TB and 37.20% of the Extra-pulmonary Tuberculosis cases were lymph node TB. 72 (53.33%) of them had completed ATT, 11 (8.2%) transfer out and 17 (12.6%) were default.
  
  
  CONCLUSIONS
  Majority of the patients presented PTB, and lymph node TB was found to be the most common EPTB. Comparatively, high efficacy of ATT was found in HIV patients visiting this resource poor setting.
authors.affiliation: Department of Gastroenterology, Bir Hospital, Kathmandu.
authors.forename: Bidhan Nidhi
authors.initials: BN
authors.lastname: Paudel
authors.affiliation: Paropakar Hospital, Thapathali, Kathmandu.
authors.forename: Punya
authors.initials: P
authors.lastname: Paudel
authors.affiliation: Kathmandu Medical College.
authors.forename: Luna
authors.initials: L
authors.lastname: Paudel
authors.affiliation: Department of Microbiology, Shree Siddhanath Science Campus, Mahendranagar, Nepal.
authors.forename: Govinda
authors.initials: G
authors.lastname: Dhungana
authors.affiliation: Department of Gastroenterology, Bir Hospital, Kathmandu.
authors.forename: Gyanendra Lal
authors.initials: GL
authors.lastname: Amatya
authors.affiliation: Nava Jeevan Hospital, Dhangagi, Nepal.
authors.forename: Choodamani
authors.initials: C
authors.lastname: Aryal
authors.affiliation: Alabama, USA.
authors.forename: Prakash
authors.initials: P
authors.lastname: Kandel
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000627:therapeutic use*; D002648:Child; D023801:Directly Observed Therapy; D005260:Female; D006801:Humans; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D009390:Nepal; D011446:Prospective Studies; D014388:Tuberculosis, Lymph Node / Q000188:drug therapy*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*; D055815:Young Adult
chemical_list: D000995:Antitubercular Agents