title: Synthesis of benzoxazoles from 2-aminophenols and β-diketones using a combined catalyst of Brønsted acid and copper iodide.
abstract: Cyclization reactions of 2-aminophenols with β-diketones catalyzed by a combination of Brønsted acid and CuI are presented. Various 2-substituted benzoxazoles were obtained through these reactions. Different substituents such as methyl, chloro, bromo, nitro, and methoxy on 2-aminophenol are tolerated under the optimized reaction conditions.
authors.affiliation: State Key Laboratory of Fine Chemicals, Dalian University of Technology , Dalian 116023, China.
authors.forename: Muhammad Shareef
authors.initials: MS
authors.lastname: Mayo
authors.forename: Xiaoqiang
authors.initials: X
authors.lastname: Yu
authors.forename: Xiaoyu
authors.initials: X
authors.lastname: Zhou
authors.forename: Xiujuan
authors.initials: X
authors.lastname: Feng
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Ming
authors.initials: M
authors.lastname: Bao