title: Acute aortic dissection with carotid and coronary malperfusion: from imaging to pathology.
abstract: Postmortem imaging, including postmortem computed tomography angiography, has become an integral tool in forensic investigation in recent years. A relatively new technique, multiphase postmortem computed tomography angiography, allows detailed visualization of the vascular system and makes it possible to evaluate the dynamic perfusion of aortic branches, including the coronary arteries. Here, we report a case of aortic dissection involving the ascending aorta (type A) with coronary and carotid malperfusion. This case illustrates the complementary use of many of the diagnostic tools that are now available in forensic practice, from imaging to conventional autopsy to pathologic techniques such as immunohistochemistry.
authors.affiliation: From the *University Center of Legal Medicine Lausanne-Geneva, Geneva University Hospitals; †Department of Pathology, Geneva University Hospitals, Geneva; ‡Department of Diagnostic and Interventional Radiology, University Hospital of Lausanne; and §University Center of Legal Medicine Lausanne-Geneva, University Hospital of Lausanne, Lausanne, Switzerland.
authors.forename: Christelle
authors.initials: C
authors.lastname: Lardi
authors.forename: Johannes-Alexander
authors.initials: JA
authors.lastname: Lobrinus
authors.forename: Francesco
authors.initials: F
authors.lastname: Doenz
authors.forename: Tony
authors.initials: T
authors.lastname: Fracasso
authors.forename: Marc
authors.initials: M
authors.lastname: Augsburger
authors.forename: Patrice
authors.initials: P
authors.lastname: Mangin
authors.forename: Silke
authors.initials: S
authors.lastname: Grabherr
mesh_terms: D001011:Aorta / Q000293:injuries* / Q000473:pathology*; D001027:Aortography; D020212:Carotid Artery Injuries / Q000000981:diagnostic imaging / Q000473:pathology*; D003324:Coronary Artery Disease / Q000473:pathology; D049429:Forensic Pathology; D006801:Humans; D021621:Imaging, Three-Dimensional; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography; D017202:Myocardial Ischemia / Q000209:etiology*; D012077:Renal Artery / Q000000981:diagnostic imaging / Q000293:injuries / Q000473:pathology