title: Medication overuse in children and adolescents.
abstract: Medication overuse is not uncommon among children and adolescents with primary headache disorders. Medication overuse in adults is associated with increased headache frequency and reduced effectiveness of acute and preventive medications. These issues probably exist in children. While withdrawal of overused medications is generally recommended, it may not result in improved headache frequency in all patients. This review summarizes what is known about predicting the response to medication withdrawal. Strategies for managing children and adolescents with medication overuse are also offered.
authors.affiliation: UCSF Headache Center, 1701 Divisadero St. Suite 480, San Francisco, CA, 94115, USA, GelfandA@neuropeds.ucsf.edu.
authors.forename: Amy A
authors.initials: AA
authors.lastname: Gelfand
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Goadsby
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage* / Q000009:adverse effects; D000700:Analgesics / Q000008:administration & dosage* / Q000009:adverse effects; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage* / Q000009:adverse effects; D004087:Dihydroergotamine / Q000008:administration & dosage* / Q000009:adverse effects; D004334:Drug Administration Schedule; D051270:Headache Disorders, Primary / Q000188:drug therapy* / Q000453:epidemiology; D051271:Headache Disorders, Secondary / Q000139:chemically induced* / Q000453:epidemiology / Q000628:therapy; D006801:Humans; D009288:Naproxen / Q000008:administration & dosage* / Q000009:adverse effects; D015995:Prevalence; D011379:Prognosis; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D004087:Dihydroergotamine; D009288:Naproxen