title: Ln[N(SiMe3 )2 ]3 -catalyzed cross-diinsertion of C≡N/C≡C into an N≡H bond: facile synthesis of 1,2,4-trisubstituted imidazoles from propargylamines and nitriles.
abstract: A lanthanide-catalyzed sequential insertion of CN and CC into an NH bond is presented. The convenient reaction, which proceeds under mild conditions, is an efficient method for preparing 1,2,4-trisubstituted imidazoles directly from readily available propargylamines and nitriles.
authors.affiliation: Department of Chemistry, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Fudan University, Shanghai 200433 (P. R. China).
authors.forename: Longcheng
authors.initials: L
authors.lastname: Hong
authors.forename: Yinlin
authors.initials: Y
authors.lastname: Shao
authors.forename: Lixin
authors.initials: L
authors.lastname: Zhang
authors.forename: Xigeng
authors.initials: X
authors.lastname: Zhou
keywords: CC coupling; imidazoles; lanthanides; nitriles; propargylamines