title: Sebaceous hyperplasia of the vulva: a series of cases reporting no association with the Muir-Torre syndrome.
abstract: Sebaceous gland hyperplasia is a common skin condition, very rarely reported in the female genital region. We present 13 cases from 12 patients, the first case series of sebaceous gland hyperplasia of the vulva. Differences in age at presentation and clinical presentation compared with classic sebaceous gland hyperplasia from the head and neck region were noted. Also, it was rarely included in the clinical differential diagnosis. Immunohistochemical studies to determine any possible association with the Muir-Torre syndrome were performed and mismatch repair protein loss was not identified.
authors.affiliation: Department of Anatomic Pathology, Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio.
authors.forename: Andres A
authors.initials: AA
authors.lastname: Roma
authors.forename: Jessica
authors.initials: J
authors.lastname: Barry
authors.forename: Rish K
authors.initials: RK
authors.lastname: Pai
authors.forename: Steven D
authors.initials: SD
authors.lastname: Billings
mesh_terms: D000293:Adolescent; D000328:Adult; D053843:DNA Mismatch Repair; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000378:metabolism / Q000473:pathology; D008875:Middle Aged; D055653:Muir-Torre Syndrome / Q000378:metabolism / Q000473:pathology*; D014844:Vulva / Q000378:metabolism / Q000473:pathology*; D014845:Vulvar Diseases / Q000378:metabolism / Q000473:pathology*; D055815:Young Adult