title: Systems biology approach to developing "systems therapeutics".
abstract: The standard drug development model uses reductionist approaches to discover small molecules targeting one pathway. Although systems biology analyzes multiple pathways, the approach is often used to develop a small molecule interacting at only one pathway in the system. Similar to that in physics where a departure from the old reductionist "Copenhagen View" of quantum physics to a new and predictive systems based, collective model has emerged yielding new breakthroughs such as the LASER, a new model is emerging in biology where systems biology is used to develop a new technology acting at multiple pathways called "systems therapeutics."
authors.affiliation: The SRM Molecular Foundry at UCSD, BioRegenerative Sciences, Inc. , San Diego, California 92014, United States.
authors.forename: Greg
authors.initials: G
authors.lastname: Maguire