title: Resistive-pulse analysis of nanoparticles.
abstract: The development of nanopore fabrication methods during the past decade has led to the resurgence of resistive-pulse analysis of nanoparticles. The newly developed resistive-pulse methods enable researchers to simultaneously study properties of a single nanoparticle and statistics of a large ensemble of nanoparticles. This review covers the basic theory and recent advances in applying resistive-pulse analysis and extends to more complex transport motion (e.g., stochastic thermal motion of a single nanoparticle) and unusual electrical responses (e.g., resistive-pulse response sensitive to surface charge), followed by a brief summary of numerical simulations performed in this field. We emphasize the forces within a nanopore governing translocation of low-aspect-ratio, nondeformable particles but conclude by also considering soft materials such as liposomes and microgels.
authors.affiliation: Department of Chemistry, University of Utah, Salt Lake City, Utah 84112; email: white@chem.utah.edu.
authors.forename: Long
authors.initials: L
authors.lastname: Luo
authors.forename: Sean R
authors.initials: SR
authors.lastname: German
authors.forename: Wen-Jie
authors.initials: WJ
authors.lastname: Lan
authors.forename: Deric A
authors.initials: DA
authors.lastname: Holden
authors.forename: Tony L
authors.initials: TL
authors.lastname: Mega
authors.forename: Henry S
authors.initials: HS
authors.lastname: White
keywords: Coulter counter; electroosmosis; electrophoresis; finite element simulation; nanoparticle detection; soft particle