title: Risk factors for development of chronic kidney disease following renal infarction: retrospective evaluation of emergency room patients from a single center.
abstract: BACKGROUND
  Previous studies have analyzed factors associated with renal infarction so that patients can be provided with earlier diagnosis and treatment. However, the factors associated with development of chronic kidney disease (CKD) following renal infarction are unknown.
  
  
  METHODS
  We retrospectively reviewed the records of patients with a diagnosis of renal infarction based on enhanced computed tomography. All patients were admitted to a single emergency department in Taiwan from 1999 to 2008. Univariate and multivariate analysis were used to assess the effect of different factors on development of CKD based on estimates of the glomerular filtration rate (eGFR) at admission and at 3-12 months after discharge.
  
  
  RESULTS
  Univariate analysis indicated significantly increased risk of CKD in patients older than 50 years, with symptoms for 24 h or less before admission, lower eGFR at admission, APACHE II score greater than 7, SOFA score greater than 1, ASA score greater than 2, and SAPS II score greater than 15. Multivariate analysis indicated that only SOFA score greater than 1 was significantly and independently associated with CKD at follow-up (p<0.001).
  
  
  CONCLUSIONS
  A total of 32.5% of patients admitted for renal infarction over a ten-year period developed CKD at 3-12 months after discharge. A SOFA score greater than 1 was significantly and independently associated with development of CKD in these patients.
authors.affiliation: Department of Emergency Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, and Chang Gung University College of Medicine, Taoyuan, Taiwan.
authors.forename: Wen-Ling
authors.initials: WL
authors.lastname: Lin
authors.affiliation: Department of Emergency Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, and Chang Gung University College of Medicine, Taoyuan, Taiwan.
authors.forename: Chen-June
authors.initials: CJ
authors.lastname: Seak
authors.affiliation: Department of Emergency Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan, and Chang Gung University College of Medicine, Taoyuan, Taiwan.
authors.forename: Jiunn-Yih
authors.initials: JY
authors.lastname: Wu
authors.affiliation: Department of Emergency Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, and Chang Gung University College of Medicine, Taoyuan, Taiwan.
authors.forename: Yi-Ming
authors.initials: YM
authors.lastname: Weng
authors.affiliation: Department of Emergency Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan, and Chang Gung University College of Medicine, Taoyuan, Taiwan.
authors.forename: Hang-Cheng
authors.initials: HC
authors.lastname: Chen
mesh_terms: D004636:Emergency Service, Hospital / Q000706:statistics & numerical data*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007238:Infarction / Q000150:complications*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010351:Patient Discharge / Q000706:statistics & numerical data; D051436:Renal Insufficiency, Chronic / Q000150:complications* / Q000503:physiopathology; D012189:Retrospective Studies; D012307:Risk Factors