title: Australian Group on Antimicrobial Resistance Community-onset Gram-negative Surveillance Program annual report, 2010.
abstract: The Australian Group on Antimicrobial Resistance (AGAR) performs regular period-prevalence studies to monitor changes in antimicrobial resistance in selected enteric Gram-negative pathogens. The 2010 survey focussed on community-onset infections, examining isolates from urinary tract infections from patients presenting to outpatient clinics, emergency departments or to community practitioners. Two thousand and ninety-two Escherichia coli, 578 Klebsiella species and 268 Enterobacter species were tested using a commercial automated method (Vitek 2, BioMérieux) and results were analysed using Clinical and Laboratory Standards Institute breakpoints from January 2012. Of the key resistances, non-susceptibility to the third-generation cephalosporin, ceftriaxone, was found in 3.2% of E. coli and 3.2%-4.0% of Klebsiella spp. Non-susceptibility rates to ciprofloxacin were 5.4% for E. coli, 1.0%-2.3% for Klebsiella spp., and 2.5%-6.6% in Enterobacter spp, and resistance rates to piperacillin-tazobactam were 2.8%, 3.2%-6.9%, and 16.8%-18.0% for the same 3 groups respectively. Only 3 strains, 2 Klebsiella spp. and 1 Enterobacter spp, were shown to harbour a carbapenemase (IMP-4).
authors.affiliation: SA Pathology (Women's and Children's Hospital), Department of Microbiology and Infectious Diseases, North Adelaide, South Australia.
authors.forename: John D
authors.initials: JD
authors.lastname: Turnidge
authors.affiliation: Department of Microbiology and Infectious Diseases, Concord, Concord, New South Wales.
authors.forename: Thomas
authors.initials: T
authors.lastname: Gottlieb
authors.affiliation: Centre for Infectious Diseases and Microbiology, Westmead Hospital, Westmead, New South Wales.
authors.forename: David H
authors.initials: DH
authors.lastname: Mitchell
authors.affiliation: Australian Collaborating Centre for Enterococcus and Staphylococcus Species (ACCESS) Typing and Research, School of Biomedical Sciences, Curtin University, Perth, Western Australia; Department of Microbiology and Infectious Diseases, PathWest Laboratory Medicine, WA, Royal Perth Hospital, Perth, Western Australia.
authors.forename: Geoffrey W
authors.initials: GW
authors.lastname: Coombs
authors.affiliation: Australian Collaborating Centre for Enterococcus and Staphylococcus Species (ACCESS) Typing and Research, School of Biomedical Sciences, Curtin University, Perth, Western Australia; Department of Microbiology and Infectious Diseases, PathWest Laboratory Medicine, WA, Royal Perth Hospital, Perth, Western Australia.
authors.forename: Julie C
authors.initials: JC
authors.lastname: Pearson
authors.affiliation: SA Pathology (Women's and Children's Hospital), Department of Microbiology and Infectious Diseases, North Adelaide, South Australia.
authors.forename: Jan M
authors.initials: JM
authors.lastname: Bell
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001315:Australia / Q000453:epidemiology; D017714:Community-Acquired Infections; D024881:Drug Resistance, Bacterial; D006090:Gram-Negative Bacteria / Q000145:classification / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D016905:Gram-Negative Bacterial Infections / Q000453:epidemiology* / Q000266:history / Q000382:microbiology*; D049674:History, 21st Century; D006801:Humans; D008826:Microbial Sensitivity Tests; D062486:Public Health Surveillance
chemical_list: D000900:Anti-Bacterial Agents