title: Epidemiology of virus-induced asthma exacerbations: with special reference to the role of human rhinovirus.
abstract: Viral respiratory infections may be associated with the virus-induced asthma in adults as well as children. Particularly, human rhinovirus is strongly suggested a major candidate for the associations of the virus-induced asthma. Thus, in this review, we reviewed and focused on the epidemiology, pathophysiology, and treatment of virus-induced asthma with special reference on human rhinovirus. Furthermore, we added our preliminary data regarding the clinical and virological findings in the present review.
authors.affiliation: Department of Respiratory Medicine, School of Medicine, Kyorin University Mitaka, Tokyo, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Saraya
authors.affiliation: Department of Respiratory Medicine, School of Medicine, Kyorin University Mitaka, Tokyo, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Kurai
authors.affiliation: Department of Respiratory Medicine, School of Medicine, Kyorin University Mitaka, Tokyo, Japan.
authors.forename: Haruyuki
authors.initials: H
authors.lastname: Ishii
authors.affiliation: Department of Respiratory Medicine, School of Medicine, Kyorin University Mitaka, Tokyo, Japan.
authors.forename: Anri
authors.initials: A
authors.lastname: Ito
authors.affiliation: Gunma Prefectural Institute of Public Health and Environmental Sciences Gunma, Japan.
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Sasaki
authors.affiliation: Gunma Prefectural Institute of Public Health and Environmental Sciences Gunma, Japan.
authors.forename: Shoichi
authors.initials: S
authors.lastname: Niwa
authors.affiliation: Kumamoto Prefectural Institute of Public Health and Environmental Sciences Kumamoto, Japan.
authors.forename: Naoko
authors.initials: N
authors.lastname: Kiyota
authors.affiliation: Gunma Prefectural Institute of Public Health and Environmental Sciences Gunma, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Tsukagoshi
authors.affiliation: Gunma Prefectural Institute of Public Health and Environmental Sciences Gunma, Japan.
authors.forename: Kunihisa
authors.initials: K
authors.lastname: Kozawa
authors.affiliation: Department of Respiratory Medicine, School of Medicine, Kyorin University Mitaka, Tokyo, Japan.
authors.forename: Hajime
authors.initials: H
authors.lastname: Goto
authors.affiliation: Department of Respiratory Medicine, School of Medicine, Kyorin University Mitaka, Tokyo, Japan.
authors.forename: Hajime
authors.initials: H
authors.lastname: Takizawa
keywords: asthma exacerbation; epidemiology; human rhinovirus; pathophysiology; treatment