title: Obstructive sleep apnoea syndrome in patients with primary open-angle glaucoma.
abstract: OBJECTIVE
  To investigate the prevalence of obstructive sleep apnoea syndrome in patients with primary open-angle glaucoma.
  
  
  METHODS
  Case series.
  
  
  METHODS
  School of Medicine, Düzce University, Turkey.
  
  
  METHODS
  Twenty-one consecutive primary open-angle glaucoma patients (12 females and 9 males) who attended the out-patient clinic of the Department of Ophthalmology between July 2007 and February 2008 were included in this study. All patients underwent polysomnographic examination.
  
  
  RESULTS
  The prevalence of obstructive sleep apnoea syndrome was 33.3% in patients with primary open-angle glaucoma; the severity of the condition was mild in 14.3% and moderate in 19.0% of the subjects. The age (P=0.047) and neck circumference (P=0.024) in patients with obstructive sleep apnoea syndrome were significantly greater than those without the syndrome. Triceps skinfold thickness in glaucomatous obstructive sleep apnoea syndrome patients reached near significance versus those without the syndrome (P=0.078). Snoring was observed in all glaucoma cases with obstructive sleep apnoea syndrome. The intra-ocular pressure of patients with primary open-angle glaucoma with obstructive sleep apnoea syndrome was significantly lower than those without obstructive sleep apnoea syndrome (P=0.006 and P=0.035 for the right and left eyes, respectively). There was no significant difference in the cup/disc ratio and visual acuity, except visual field defect, between primary open-angle glaucoma patients with and without obstructive sleep apnoea syndrome.
  
  
  CONCLUSIONS
  Although it does not provide evidence for a cause-effect relationship, high prevalence of obstructive sleep apnoea syndrome in patients with primary open-angle glaucoma in this study suggests the need to explore the long-term results of coincidence, relationship, and cross-interaction of these two common disorders.
authors.affiliation: Department of Chest Diseases, Faculty of Medicine, Düzce University, 81620 Düzce, Turkey.
authors.forename: Ege G
authors.initials: EG
authors.lastname: Balbay
authors.affiliation: Department of Chest Diseases, Faculty of Medicine, Düzce University, 81620 Düzce, Turkey.
authors.forename: Oner
authors.initials: O
authors.lastname: Balbay
authors.affiliation: Department of Chest Diseases, Faculty of Medicine, Düzce University, 81620 Düzce, Turkey.
authors.forename: Ali N
authors.initials: AN
authors.lastname: Annakkaya
authors.affiliation: Department of Chest Diseases, Faculty of Medicine, Düzce University, 81620 Düzce, Turkey.
authors.forename: Kezban O
authors.initials: KO
authors.lastname: Suner
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Düzce University, 81620 Düzce, Turkey.
authors.forename: Harun
authors.initials: H
authors.lastname: Yuksel
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Düzce University, 81620 Düzce, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Tunç
authors.affiliation: Department of Chest Diseases, Faculty of Medicine, Düzce University, 81620 Düzce, Turkey.
authors.forename: Peri
authors.initials: P
authors.lastname: Arbak
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005902:Glaucoma, Open-Angle; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000150:complications / Q000453:epidemiology* / Q000473:pathology; D014421:Turkey / Q000453:epidemiology
keywords: Glaucoma, open-angle; Sleep apnea, obstructive; Turkey