title: Flavonoids and other constituents from Aletris spicata and their chemotaxonomic significance.
abstract: Eleven compounds, including four flavonoids [(2R,3R)-2,3-dihydro-3,5-dihydroxy-7,4'-dimethoxyflavone (1), 5-hydroxy-7,8,4'-trimethoxy-flavone (2), amentoflavone (10) and apigenin (11)], two penylpropanoids [sinapaldehyde (3) and 3-methoxy-4-hydroxy-cinnamic aldehyde (4)], three phenolic acids [4-hydroxyl-3,5-dimethoxy-benzaldehyde (5), 4-hydroxyacetophen-one (6) and p-hydroxybenzaldehyde (7)], one furan derivative [5-hydroxymethyl furfural (8)] and one steroid saponin [β-sitosterol-3-O-β-d-glucoside (9)], were isolated and identified from Aletris spicata. Among them, compounds 1-7, 9 and 10 were reported from the genus Aletris for the first time. Furthermore, seven of them (1-6, 10) were obtained from the family Liliaceae for the first time. Chemotaxonomy of the isolated compounds is discussed briefly.
authors.affiliation: a Department of Natural Medicinal Chemistry , China Pharmaceutical University , #24 Tongjiaxiang, Nanjing 210009 , P.R. China.
authors.forename: Lin-Zhen
authors.initials: LZ
authors.lastname: Li
authors.forename: Meng-Hua
authors.initials: MH
authors.lastname: Wang
authors.forename: Jian-Bo
authors.initials: JB
authors.lastname: Sun
authors.forename: Jing-Yu
authors.initials: JY
authors.lastname: Liang
mesh_terms: D047310:Apigenin / Q000737:chemistry / Q000302:isolation & purification; D001547:Benzaldehydes / Q000737:chemistry; D047309:Flavones / Q000737:chemistry / Q000302:isolation & purification; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D005662:Furaldehyde / Q000031:analogs & derivatives / Q000737:chemistry; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification; D019668:Liliaceae / Q000737:chemistry*; D019684:Magnoliopsida / Q000737:chemistry*; D010802:Phylogeny; D010946:Plants, Medicinal / Q000737:chemistry*; D012855:Sitosterols / Q000737:chemistry
chemical_list: D001547:Benzaldehydes; D047309:Flavones; D005419:Flavonoids; D005960:Glucosides; D012855:Sitosterols; C025473:gamma-sitosterol; C008046:5-hydroxymethylfurfural; D047310:Apigenin; D005662:Furaldehyde; C011483:4-hydroxybenzaldehyde; C043562:flavone; C032175:benzaldehyde
keywords: Aletris spicata; Chemotaxonomy; Nartheciaceae