title: Validation of automated quantification of myocardial perfusion single-photon emission computed tomography using Heart Score View in patients with known or suspected coronary artery disease.
abstract: Heart Score View (HSV) is a free software package for automated quantification of myocardial single photon emission computed tomography (SPECT) imaging using a standard Windows computer. We compared scoring results of myocardial perfusion among visual analysis, Quantitative Perfusion SPECT (QPS), and HSV in patients with known or suspected coronary artery disease.This study included 75 consecutive patients with known or suspected coronary artery disease who underwent adenosive stress-rest Tl-201 SPECT. Analysis of myocardial perfusion SPECT was performed on a standard 17-segment model visually and using QPS and HSV.There were 54 male and 21 female patients with a mean age of 70.5 ± 10.7 years. Thirteen patients (17%) had prior myocardial infarction. Summed stress score (SSS) and summed rest score (SRS) in the mid and basal areas were significantly higher on HSV than visual analysis or QPS. There was no significant difference in SDS in the whole area among the 3 methods. Similar results were found even in patients without prior myocardial infarction. Manual setting of the left ventricular cavity improved the correlations of SSS, SRS and SDS between HSV and the other methods.Our data suggested that HSV was comparable with visual analysis or QPS in scoring myocardial perfusion when manual setting of the left ventricular cavity is applied.
authors.affiliation: Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences.
authors.forename: Toshitaka
authors.initials: T
authors.lastname: Iwasaki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kurisu
authors.forename: Nobukazu
authors.initials: N
authors.lastname: Abe
authors.forename: Megumi
authors.initials: M
authors.lastname: Tamura
authors.forename: Noriaki
authors.initials: N
authors.lastname: Watanabe
authors.forename: Hiroki
authors.initials: H
authors.lastname: Ikenaga
authors.forename: Takashi
authors.initials: T
authors.lastname: Shimonaga
authors.forename: Tadanao
authors.initials: T
authors.lastname: Higaki
authors.forename: Ken
authors.initials: K
authors.lastname: Ishibashi
authors.forename: Naoya
authors.initials: N
authors.lastname: Mitsuba
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Dohi
authors.forename: Yasuki
authors.initials: Y
authors.lastname: Kihara
mesh_terms: D000368:Aged; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003326:Coronary Circulation / Q000502:physiology*; D001330:Electronic Data Processing; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D055414:Myocardial Perfusion Imaging / Q000379:methods*; D012372:ROC Curve; D015203:Reproducibility of Results; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*