title: [Quantifying the chemical composition of crack-cocaine (bazuco) samples seized in Colombia during the first half of 2010].
abstract: OBJECTIVE
  Quantifying crack-cocaine (known locally as bazuco or smokable cocaine base paste-PBC) use and identifying other components in study conditions regarding samples of crack-cocaine seized in Colombia and held by the Colombian Institute of Legal Medicine and Forensic Science Narcotics Laboratory in Bogota during the first half of 2010.
  
  
  METHODS
  A cross-sectional, exploratory analytical study was carried out for chemically characterizing crack-cocaine samples by the gas chromatography analytical methodology using ion trap mass spectrometry developed and validated in the Universidad National de Colombia's Medicine Faculty's Toxicology Laboratory in Bogota.
  
  
  RESULTS
  A 4 % to 70 % w/w cocaine base concentration was found in the 109 samples tested (37 % w/w mean); 73 % of the samples had 20 % to 50 % w/w concentration. Other coca alkaloids were identified, such astropacocaine, trans-cinnamoylcocaine, norcocaine and ecgonine methyl ester. Caffeine was identified as an adulterantin 57 % of the samples and phenacetin in 2.8 % of them.
  
  
  CONCLUSIONS
  The toxicological significance of the results concerning crack-cocaine consumers was quantified, given the profile for chronic users.
authors.affiliation: Universidad Nacional de Colombia, Bogotá, jssabogalc@unal.edu.co.
authors.forename: Juan S
authors.initials: JS
authors.lastname: Sabogal-Carmona
authors.affiliation: Universidad Nacional de Colombia, Bogotá, jssabogalc@unal.edu.co.
authors.forename: José R
authors.initials: JR
authors.lastname: Urrego-Novoa
mesh_terms: D003105:Colombia; D016578:Crack Cocaine / Q000737:chemistry*; D004335:Drug and Narcotic Control
chemical_list: D016578:Crack Cocaine