title: "Click" chemistry mildly stabilizes bifunctional gold nanoparticles for sensing and catalysis.
abstract: A large family of bifunctional 1,2,3-triazole derivatives that contain both a polyethylene glycol (PEG) chain and another functional fragment (e.g., a polymer, dendron, alcohol, carboxylic acid, allyl, fluorescence dye, redox-robust metal complex, or a β-cyclodextrin unit) has been synthesized by facile "click" chemistry and mildly coordinated to nanogold particles, thus providing stable water-soluble gold nanoparticles (AuNPs) in the size range 3.0-11.2 nm with various properties and applications. In particular, the sensing properties of these AuNPs are illustrated through the detection of an analogue of a warfare agent (i.e., sulfur mustard) by means of a fluorescence "turn-on" assay, and the catalytic activity of the smallest triazole-AuNPs (core of 3.0 nm) is excellent for the reduction of 4-nitrophenol in water.
authors.affiliation: ISM, UMR CNRS 5255, Université Bordeaux, 351 Cours de la Libération, 33405 Talence Cedex, (France).
authors.forename: Na
authors.initials: N
authors.lastname: Li
authors.forename: Pengxiang
authors.initials: P
authors.lastname: Zhao
authors.forename: Na
authors.initials: N
authors.lastname: Liu
authors.forename: María
authors.initials: M
authors.lastname: Echeverria
authors.forename: Sergio
authors.initials: S
authors.lastname: Moya
authors.forename: Lionel
authors.initials: L
authors.lastname: Salmon
authors.forename: Jaime
authors.initials: J
authors.lastname: Ruiz
authors.forename: Didier
authors.initials: D
authors.lastname: Astruc
mesh_terms: D002384:Catalysis; D002619:Chemical Warfare Agents / Q000032:analysis; D057930:Click Chemistry; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry; D009151:Mustard Gas / Q000032:analysis; D009596:Nitrophenols / Q000737:chemistry; D010084:Oxidation-Reduction; D010316:Particle Size; D011092:Polyethylene Glycols / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D014230:Triazoles / Q000737:chemistry
chemical_list: D002619:Chemical Warfare Agents; D009596:Nitrophenols; D014230:Triazoles; D011092:Polyethylene Glycols; D006046:Gold; D009151:Mustard Gas; C024836:4-nitrophenol
keywords: click chemistry; fluorescence; gold; nanoparticles; reduction; sulfur-mustard analogues