title: Use of oxycodone in pain management.
abstract: Oxycodone is widely used to alleviate moderate-to severe acute pain, It is an effective analgesic for many types of pain, and is especially useful for paroxysmal spontaneous pain, steady pain, allodynia associated with postherpetic neuralgia, and it is also increasingly used in the management of cancer-related and chronic pain, oxycodone has been found to improve the quality of life of patients with many types of pain. In 2011, following chemical and physical manipulation, an extended-release form of oxycodone was developed in order to maintain its rate-controlling mechanism. This new formulation significantly improved analgesia among patients with moderate-to-severe chronic osteoarthritis pain with an adverse event profile similar to that of other opioids. The long-term safety and efficacy of extended-release form of oxycodone in relieving moderate-to-severe chronic pain has been demonstrated. In this study we discussed about different aspects of this drug in managing of various types of pain.
authors.affiliation: Development Association of Clinical Studies (DACS), Tehran University of Medical Sciences (TUMS), Tehran, Iran ; Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences (TUMS), Tehran, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Moradi
authors.affiliation: Development Association of Clinical Studies (DACS), Tehran University of Medical Sciences (TUMS), Tehran, Iran ; Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences (TUMS), Tehran, Iran.
authors.forename: Sara
authors.initials: S
authors.lastname: Esmaeili
authors.affiliation: Development Association of Clinical Studies (DACS), Tehran University of Medical Sciences (TUMS), Tehran, Iran ; Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences (TUMS), Tehran, Iran.
authors.forename: Saeed
authors.initials: S
authors.lastname: Shoar
authors.affiliation: Department of Anesthesiology, Rasoul Akram Medical Center, Tehran university of Medical Sciences (TUMS), Tehran, Iran.
authors.forename: Saeid
authors.initials: S
authors.lastname: Safari
keywords: Analgesics, Opioid; Oxycodone; Pain