title: Use of BioGlue Surgical Adhesive in Hypospadias Repair.
abstract: OBJECTIVE
  To prospectively evaluate the efficacy of albumin glutaraldehyde tissue adhesive (BioGlue) in the surgical treatment of patients with hypospadias.
  
  
  METHODS
  Two groups of 20 patients each who underwent hypospadias repair were included in the study. In the first group we utilized BioGlue as an additional protective layer to the suture line of the neo-urethra, while patients in the second group were operated on utilizing a routine surgical technique.
  
  
  RESULTS
  There were no statistical differences between patients from the 2 groups in terms of surgical complications. Urethrocutaneous fistula was revealed in 4 (20%) patients after repair with BioGlue and in 3 (15%) patients from the control group (p = 0.686), suture line breakdown in 4 (20%) and in 1 (5%) patients (p = 0.478), meatal stenosis in 1 (5%) and in 1 (5%) patient (p = 1). Furthermore more patients in the BioGlue group (n = 12, 60%) demonstrated poor cosmetic results compared to the control group where most patients - 19 (95%) had acceptable cosmetic outcomes (p = 0.007).
  
  
  CONCLUSIONS
  Our data showed no benefits of BioGlue use in hypospadias repair.
authors.affiliation: Department of Pediatric Urology, Shaare Zedek Medical Center, Faculty of Medical Science, Hebrew University, Jerusalem, Israel.
authors.forename: Stanislav
authors.initials: S
authors.lastname: Kocherov
authors.affiliation: Department of Pediatric Urology, Shaare Zedek Medical Center, Faculty of Medical Science, Hebrew University, Jerusalem, Israel.
authors.forename: Genady
authors.initials: G
authors.lastname: Lev
authors.affiliation: Department of Pediatric Urology, Shaare Zedek Medical Center, Faculty of Medical Science, Hebrew University, Jerusalem, Israel.
authors.forename: Boris
authors.initials: B
authors.lastname: Chertin
keywords: BioGlue; Hypospadias; Hypospadias repair; Urethrocutaneous fstula