title: The role of alginates in regulation of food intake and glycemia: a gastroenterological perspective.
abstract: Regulation of food intake through modulation of gastrointestinal responses to ingested foods is an ever-growing component of the therapeutic approaches targeting the obesity epidemic. Alginates, viscous and gel-forming soluble fibers isolated from the cell wall of brown seaweeds and some bacteria, are recently receiving considerable attention because of their potential role in satiation, satiety, and food intake regulation in the short term. Enhancement of gastric distension, delay of gastric emptying, and attenuation of postprandial glucose responses may constitute the basis of their physiological benefits. Offering physical, chemical, sensorial, and physiological advantages over other viscous and gel-forming fibers, alginates constitute promising functional food ingredients for the food industry. Therefore, the current review explores the role of alginates in food intake and glycemic regulation, their underlying modes of action and their potential in food applications.
authors.affiliation: a Department of Nutritional Sciences, Faculty of Medicine, University of Toronto , Toronto , M5S 3E2 , ON , Canada.
authors.forename: D
authors.initials: D
authors.lastname: El Khoury
authors.forename: H D
authors.initials: HD
authors.lastname: Goff
authors.forename: G H
authors.initials: GH
authors.lastname: Anderson
mesh_terms: D000464:Alginates / Q000008:administration & dosage / Q000494:pharmacology*; D001786:Blood Glucose / Q000187:drug effects*; D004435:Eating / Q000187:drug effects*; D019649:Food Industry; D005746:Gastric Emptying / Q000187:drug effects*; D006801:Humans; D019518:Postprandial Period / Q000502:physiology; D012527:Satiation / Q000187:drug effects*
chemical_list: D000464:Alginates; D001786:Blood Glucose
keywords: Fiber; gelling; glucose; obesity; satiety; viscous