title: Analysis of the association of polymorphic loci rs917997 in IL18RAP gene and rs187238 in IL18 gene with the risk for non-Hodgkin's malignant lymphomas in Novosibirsk population.
abstract: We analyzed the association of polymorphic variants of rs917997 (G/A) locus in IL18RAP gene and rs187238 (G/C) locus in IL18 gene with the risk of malignant non-Hodgkin's lymphomas in Novosibirsk population. Allele and genotype frequencies of the above loci were determined in patients (243 persons) and control group (371 persons) and compared using χ(2) test. None of the analyzed loci showed statistically significant association with the risk of malignant non-Hodgkin's lymphomas.
authors.affiliation: Institute of Chemical Biology and Fundamental Medicine, Siberian Division of Russian Academy of Sciences, Novosibirsk, Russia.
authors.forename: M N
authors.initials: MN
authors.lastname: Surovtseva
authors.forename: A S
authors.initials: AS
authors.lastname: Vainer
authors.forename: O V
authors.initials: OV
authors.lastname: Berezina
authors.forename: V S
authors.initials: VS
authors.lastname: Ovchinnikov
authors.forename: E N
authors.initials: EN
authors.lastname: Voropaeva
authors.forename: T I
authors.initials: TI
authors.lastname: Pospelova
authors.forename: M L
authors.initials: ML
authors.lastname: Filipenko
mesh_terms: D000328:Adult; D000368:Aged; D000483:Alleles; D016022:Case-Control Studies; D005260:Female; D005787:Gene Frequency; D056426:Genetic Loci; D005838:Genotype; D006801:Humans; D020382:Interleukin-18 / Q000235:genetics* / Q000276:immunology; D008228:Lymphoma, Non-Hodgkin / Q000235:genetics* / Q000276:immunology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D060787:Neoplasm Grading; D020641:Polymorphism, Single Nucleotide; D053724:Receptors, Interleukin-18 / Q000235:genetics* / Q000276:immunology; D012306:Risk; D012800:Siberia
chemical_list: C000589760:IL18 protein, human; D020382:Interleukin-18; D053724:Receptors, Interleukin-18