title: Comparing GlideScope Video Laryngoscope and Macintosh Laryngoscope Regarding Hemodynamic Responses During Orotracheal Intubation: A Randomized Controlled Trial.
abstract: BACKGROUND
  To determine if the GlideScope® videolaryngoscope (GVL) could attenuate the hemodynamic responses to orotracheal intubation compared with conventional Macintosh laryngoscope.
  
  
  OBJECTIVE
  The aim of this relatively large randomized trial was to compare the hemodynamic stress responses during laryngoscopy and tracheal intubation using GVL versus MCL amongst healthy adult individuals receiving general anesthesia for elective surgeries.
  
  
  METHODS
  Ninety five healthy adult patients with American Society of Anesthesiologists physical status class I or II that were scheduled for elective surgery under general anesthesia were randomly allocated to either Macintosh or GlideScope arms. All patients received a standardized protocol of general anesthesia. Hemodynamic changes associated with intubation were recorded before and at 1, 3 and 5 minutes after the intubation. The time taken to perform endotracheal intubation was also noted in both groups.
  
  
  RESULTS
  Immediately before laryngoscopy (pre-laryngoscopy), the values of all hemodynamic variables did not differ significantly between the two groups (All P values > 0.05). Blood pressures and HR values changed significantly over time within the groups. Time to intubation was significantly longer in the GlideScope (15.9 ± 6.7 seconds) than in the Macintosh group (7.8 ± 3.7 sec) (P< 0.001). However, there were no significant differences between the two groups in hemodynamic responses at all time points.
  
  
  CONCLUSIONS
  The longer intubation time using GVL suggests that the benefit of GVL could become apparent if the time taken for orotracheal intubation could be decreased in GlideScope group.
authors.affiliation: Department of Anaesthesiology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Ali Reza
authors.initials: AR
authors.lastname: Pournajafian
authors.affiliation: Department of Anaesthesiology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Ghodraty
authors.affiliation: Department of Anaesthesiology, Rasoul-Akram Medical Center, Iran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Seyed Hamid Reza
authors.initials: SH
authors.lastname: Faiz
authors.affiliation: Department of Anaesthesiology, Rasoul-Akram Medical Center, Iran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Poupak
authors.initials: P
authors.lastname: Rahimzadeh
authors.affiliation: Department of Research, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Hamidreza
authors.initials: H
authors.lastname: Goodarzynejad
authors.affiliation: Department of Anaesthesiology, Rasoul-Akram Medical Center, Iran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Enseyeh
authors.initials: E
authors.lastname: Dogmehchi
keywords: Hemodynamic Responses; Intubation; Laryngoscopes