title: Vitamin K1 antagonisation is not safe in high thromboembolic risk patients with over-anticoagulation.
abstract: We report a case of a fatal massive anterior acute myocardial infarction (AMI) after administration of vitamin K1 for over-anticoagulation following cardioembolism from mechanical mitroaortic valve prostheses associated with atrial fibrillation.
authors.affiliation: Réanimation médicale et toxicologique, Hôpital Lariboisière, Paris, France.
authors.forename: Sébastien
authors.initials: S
authors.lastname: Champion
authors.affiliation: Réanimation médicale et toxicologique, Hôpital Lariboisière, Paris, France.
authors.forename: Cédric
authors.initials: C
authors.lastname: Cleophax
authors.affiliation: Réanimation médicale et toxicologique, Hôpital Lariboisière, Paris, France - Cardiologie, Hôpital Lariboisière, Paris, France.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Voicu
authors.affiliation: Cardiologie, Hôpital Lariboisière, Paris, France.
authors.forename: Marc
authors.initials: M
authors.lastname: Sirol
authors.affiliation: Réanimation médicale et toxicologique, Hôpital Lariboisière, Paris, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Deye
authors.affiliation: Réanimation médicale et toxicologique, Hôpital Lariboisière, Paris, France.
authors.forename: Frédéric
authors.initials: F
authors.lastname: J Baud
mesh_terms: D000369:Aged, 80 and over; D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000150:complications / Q000188:drug therapy; D017809:Fatal Outcome; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D009203:Myocardial Infarction / Q000209:etiology* / Q000503:physiopathology; D013923:Thromboembolism / Q000209:etiology* / Q000503:physiopathology; D010837:Vitamin K 1 / Q000008:administration & dosage* / Q000009:adverse effects
chemical_list: D000925:Anticoagulants; D010837:Vitamin K 1