title: Six-minute walk distance is an independent predictor of hospital readmission in patients with chronic heart failure.
abstract: Patients with chronic heart failure (CHF) are frequently readmitted to the hospital due to disease progression. Although a shorter 6-minute walk distance (6MWD) is correlated with poor prognosis, 6MWD is not considered a clinical indicator for predicting hospital readmission.We investigated whether 6MWD measured at the time of hospital discharge predicted readmission due to heart failure in CHF patients.Patients admitted to the hospital for the first time due to heart failure were enrolled. After 6MWD was measured at discharge, patients were followed-up for 3 years. Clinical characteristics, 6MWD and readmission due to heart failure were evaluated in 252 patients (68.5 ± 11.8 years old, 162 males). Significant factors that affected readmission were extracted and cut-off values were determined using multivariate logistic regression analysis and receiver operating characteristic curves.Of 252 CHF patients, 103 were readmitted within 3 years. 6MWD at the time of discharge was significantly shorter in readmitted patients than non-readmitted patients (P < 0.001) and was a significant predictor of readmission (P < 0.001). The odds ratio for readmission was 1.22 (P < 0.001) with each 10-meter decrease in 6MWD. The 6MWD cut-off value was determined to be 390 meters, with a sensitivity of 0.75 and a specificity of 0.77.6MWD measured at the time of discharge is an independent predictor of hospital readmission in CHF patients, with a cut-off value of 390 meters.
authors.affiliation: Department of Cardiovascular Medicine, Kitasato University Graduate School of Medical Sciences.
authors.forename: Minoru
authors.initials: M
authors.lastname: Tabata
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Shimizu
authors.forename: Daisuke
authors.initials: D
authors.lastname: Kamekawa
authors.forename: Michitaka
authors.initials: M
authors.lastname: Kato
authors.forename: Kentaro
authors.initials: K
authors.lastname: Kamiya
authors.forename: Ayako
authors.initials: A
authors.lastname: Akiyama
authors.forename: Yumi
authors.initials: Y
authors.lastname: Kamada
authors.forename: Shinya
authors.initials: S
authors.lastname: Tanaka
authors.forename: Chiharu
authors.initials: C
authors.lastname: Noda
authors.forename: Takashi
authors.initials: T
authors.lastname: Masuda
mesh_terms: D005080:Exercise Test / Q000379:methods*; D017079:Exercise Tolerance; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000175:diagnosis* / Q000503:physiopathology / Q000534:rehabilitation; D006801:Humans; D007902:Length of Stay / Q000639:trends; D008297:Male; D008875:Middle Aged; D010359:Patient Readmission; D011237:Predictive Value of Tests; D012372:ROC Curve; D012189:Retrospective Studies; D013997:Time Factors; D016138:Walking