title: Radiological and Histological Evaluation of the Effects of Cortical Perforations on Bone Healing in Mandibular Onlay Graft Procedures.
abstract: BACKGROUND
  Perforations of the cortical bone may be an advantage for the success of the autogenous bone graft procedure, but whether this perforation has a positive effect on the bone remains controversial.
  
  
  OBJECTIVE
  This study evaluates the effects of cortical perforation of the autogenous bone block graft radiologically and histologically.
  
  
  METHODS
  Seven adult pigs were used for this study. On the experimental side, cortical perforation at the host site was prepared, while no perforation was done on the control side. The specimens were evaluated, and the Wilcoxon signed-rank test was used for statistical analysis.
  
  
  RESULTS
  In the radiological evaluation, the Wilcoxon signed-rank test indicated no significant differences in densities among the grafts (p = .23) with a mean of 4.29 ± 0.951 for the unperforated graft side and 3.57 ± 0.976 for the decorticated graft side. In histological evaluation, there was a significant difference in the thickness of the grafts between the groups (experimental group 3.71 ± 1.286, control group: 4.71 ± 0.488; p = .033). However, when the remodeling and osteoblastic activity in the grafts were measured, no significant differences were observed between the groups (p = 1 and p = .133, respectively).
  
  
  CONCLUSIONS
  In augmentation with mandibular onlay bone grafts, cortical perforations in the recipient site make no distinct contribution to bone healing within 12 weeks.
authors.affiliation: Private practice, Ankara, Turkey.
authors.forename: Emre
authors.initials: E
authors.lastname: Dayangac
authors.affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Baskent University, Ankara, Turkey.
authors.forename: Kenan
authors.initials: K
authors.lastname: Araz
authors.affiliation: Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Baskent University, Ankara, Turkey.
authors.forename: Yener
authors.initials: Y
authors.lastname: Oguz
authors.affiliation: Experimental Research Center, Faculty of Medicine, Baskent University, Ankara, Turkey.
authors.forename: Didem
authors.initials: D
authors.lastname: Bacanli
authors.affiliation: Department of Pathology, Faculty of Medicine, Baskent University, Ankara, Turkey.
authors.forename: Berrin
authors.initials: B
authors.lastname: Caylak
authors.affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Baskent University, Ankara, Turkey.
authors.forename: Sina
authors.initials: S
authors.lastname: Uckan
mesh_terms: D000818:Animals; D015519:Bone Density; D001861:Bone Regeneration; D016723:Bone Remodeling; D001862:Bone Resorption; D016025:Bone Transplantation / Q000379:methods*; D007284:Inlays; D008334:Mandible / Q000000981:diagnostic imaging / Q000601:surgery*; D013552:Swine; D014945:Wound Healing / Q000502:physiology*
keywords: autogenous bone graft; bone augmentation; cortical perforation; edentulous mandible