title: Necrotizing Cervical Lymphadenitis Caused by Mycobacterium simiae in an HIV-Positive Patient: Imaging with (18)F-FDG PET/CT.
abstract: Mycobacterium simiae (M. simiae) is an opportunistic pathogen rarely associated with human disease, although in recent years M. simiae has been detected with increasing frequency in human immunodeficiency virus (HIV)-infected patients, usually causing disseminated infection with fever, diarrhea and weight loss. We report the case of an HIV-positive man, who was referred for an (18)F-FDG PET/CT to evaluate a solitary pulmonary nodule. The PET/CT showed incidental large necrotic cervical lymph nodes, compatible with necrotizing cervical lymphadenitis. Biopsy and culture of one of the affected lymph nodes were positive for M. simiae. We present the first report of (18)F-FDG PET/CT imaging of an infectious process caused by M. simiae in humans.
authors.affiliation: Department of Nuclear Medicine, Brandon Regional Health Centre, 150 McTavish Ave E, Brandon, MB R7A 2B3 Canada.
authors.forename: William
authors.initials: W
authors.lastname: Makis
authors.affiliation: Department of Nuclear Medicine, Jewish General Hospital, McGill University, 3755 Cote Ste Catherine Road, Montreal, QC H3T 1E2 Canada.
authors.forename: Christopher
authors.initials: C
authors.lastname: Rush
keywords: Fluorodeoxyglucose; HIV; Mycobacterium simiae; Necrotizing cervical lymphadenitis; PET/CT