title: Dioxins in the semen of men with infertility.
abstract: The purpose of the present study was to assess ejaculate contamination by polychlorinated dibenzo-p-dioxins/furans in male infertility. The database of 168 infertile and 49 fertile men was included in the study. Dioxin content was determined using gas chromatography/high-resolution mass spectrometry (GC/HRMS). In the ejaculate of infertile men, the content of dioxins and furans was 2.2-2.3 times higher than in fertile donors. The maximum level of the most toxic dioxin congener was detected in pathospermia. Contamination of semen of infertile men by polychlorinated dibenzo-p-dioxins/furans supports the hypothesis about the relationship between environmental factors and reproductive health.
authors.affiliation: Central Research Laboratory, Bashkir State Medical University, 450000, Ufa, Russia. efgalimova@mail.ru.
authors.forename: E F
authors.initials: EF
authors.lastname: Galimova
authors.affiliation: State-financed Institution of the Republic of Bashkortostan Environmental Research and Protection Center, 450075, Ufa, Russia. ecocnt@ufanet.ru.
authors.forename: Z K
authors.initials: ZK
authors.lastname: Amirova
authors.affiliation: Department of Biochemistry, Bashkir State Medical University, 450000, Ufa, Russia. sngalim@mail.ru.
authors.forename: Sh N
authors.initials: ShN
authors.lastname: Galimov
mesh_terms: D000328:Adult; D001572:Benzofurans / Q000032:analysis; D000072338:Dibenzofurans, Polychlorinated; D004542:Ejaculation; D004785:Environmental Pollutants / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007248:Infertility, Male / Q000503:physiopathology; D008297:Male; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives* / Q000032:analysis; D012661:Semen / Q000737:chemistry*; D055815:Young Adult
chemical_list: D001572:Benzofurans; D000072338:Dibenzofurans, Polychlorinated; D004785:Environmental Pollutants; D000072317:Polychlorinated Dibenzodioxins
keywords: Dioxins; Ejaculate; Furans; Male infertility; POP