title: Single foci prostate cancer: current diagnosis and management.
abstract: Diagnosis of small prostate cancer foci is a real challenge for pathologists and urologists as it carries the risk of false positive or negative diagnosis with clinical consequences. Diagnosis of small prostate cancer foci requires a strict methodological approach which includes a search for major and minor features under low and high magnification. Ambiguous cases can be further clarified with the use of basal cell immunomarkers complemented by a positive indicator of malignancy. Despite the new diagnostic armamentarium, a few cases will continue to remain doubtful and might require an appropriate rebiopsy.
authors.affiliation: Department of Urology, General Hospital of Kalamata, Kalamata, Greece.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Efthimiou
authors.affiliation: Department of Urology, General Hospital of Kalamata, Kalamata, Greece.
authors.forename: Konstadinos
authors.initials: K
authors.lastname: Skrepetis
authors.affiliation: Pathology, General Hospital of Kalamata, Kalamata, Greece.
authors.forename: Elefteria
authors.initials: E
authors.lastname: Bournia
keywords: Prostate cancer; Single foci