title: Diagnostic value of magnetic resonance cholangiopancreatography for secondary common bile duct stones compared with laparoscopic trans-cystic common bile duct exploration.
abstract: BACKGROUND
  The aim of this study was to evaluate the diagnostic potential of magnetic resonance cholangiopancreatography (MRCP) in preoperative patients with secondary common bile duct stones during the application of laparoscopic trans-cystic common bile duct exploration (LTCBDE).
  
  
  METHODS
  The clinical records of 255 patients were retrospectively analyzed. All patients included in the study were examined by MRCP 3 days prior to LTCBDE.
  
  
  RESULTS
  Secondary bile duct stones were detected in 220 patients using LTCBDE. Of the patients diagnosed by MRCP, 141 were true-positive, 28 were true-negative, 7 were false-positive and 79 were false-negative. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of MRCP for secondary common bile duct stones were 64.09%, 80.00%, 66.27%, 95.27%, and 26.17%, respectively. When the cases with muddy stones were excluded, the outcomes were 80.41%, 79.41%, 69.23%, 94.44%, and 48.21%, respectively. When cases with stones <3 mm (inclusive) in diameter were excluded, the outcomes were 93.75%, 79.41%, 86.27%, 93.75%, and 65.85%, respectively. When cases with stones <5 mm (inclusive) in diameter were excluded, the outcomes were 93.10%, 79.41%, 89.26%, 92.05%, and 81.82%, respectively.
  
  
  CONCLUSIONS
  The effectiveness of preoperative MRCP is overestimated for the diagnosis of secondary common bile duct stones, particularly for muddy and micro-stones.
authors.affiliation: Department of Comprehensive Surgery, Medical and Health Center, Beijing Friendship Hospital affiliated to Capital Medical University, Beijing, China (mainland).
authors.forename: Peixin
authors.initials: P
authors.lastname: Li
authors.affiliation: Department of General Surgery, Beijing Friendship Hospital Affiliated to Capital Medical Universit, Beijing, China (mainland).
authors.forename: Zhongtao
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Department of General Surgery, Beijing Friendship Hospital Affiliated to Capital Medical Universit, Beijing, China (mainland).
authors.forename: Jianshe
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of General Surgery, Beijing Friendship Hospital Affiliated to Capital Medical Universit, Beijing, China (mainland).
authors.forename: Lan
authors.initials: L
authors.lastname: Jin
authors.affiliation: Department of General Surgery, Beijing Friendship Hospital Affiliated to Capital Medical Universit, Beijing, China (mainland).
authors.forename: Wei
authors.initials: W
authors.lastname: Han
authors.affiliation: Department of Medical Imaging, Beijing Friendship Hospital Affiliated to Capital Medical University, Beijing, China (mainland).
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D049448:Cholangiopancreatography, Magnetic Resonance; D017081:Cholecystectomy, Laparoscopic; D003135:Common Bile Duct / Q000473:pathology* / Q000601:surgery*; D005189:False Positive Reactions; D005260:Female; D042882:Gallstones / Q000175:diagnosis* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D055815:Young Adult