title: [Impact of the Royal Decree-Law 16/2012 on the number of prescriptions and pharmaceutical expenditures].
abstract: BACKGROUND
  this research aims to understand if the consequences on drug expenditures and number of prescriptions of Royal Decree-Law 16/2012 as estimated by the Ministry of Health, Social Services and Equality (MHSSE) are similar to those found by using common statistical approaches. In addition, several models have been built to forecast the evolution of both variables for the period September 2013-December 2014.
  
  
  METHODS
  the Box-Jenkins methodology and the Box-Tiao intervention analysis were applied to data of the period 2003-13 to forecast the monthly values of the number of prescriptions and pharmaceutical expenditures. Forecasts were used in a counter-factual analysis to be compared to the actual values of prescriptions and drug expenditures. Moreover, forecasts for the period September 2013 to December 2014 were obtained to observe the impact of the policy in the future.
  
  
  RESULTS
  the counterfactual analysis estimated a decrease in the number of prescriptions of 12.18% and 12.83% in the pharmaceutical expenditure; these figures were 12,75% and 14,03% respectively, when the intervention analysis was used.
  
  
  CONCLUSIONS
  the estimated reduction in the number of prescriptions for the period June 2012-August 2013 was similar to the figure offered by the MHSSE, while the reduction in the drug expenditure series was smaller. The Box-Jenkins methodology generated low forecast errors (less than 3%) what makes this procedure useful to reliably anticipate future consumptions.
authors.forename: Fernando
authors.initials: F
authors.lastname: Antoñanzas Villar
authors.forename: Roberto
authors.initials: R
authors.lastname: Rodríguez-Ibeas
authors.forename: Carmelo A
authors.initials: CA
authors.lastname: Juárez-Castelló
authors.forename: Ma Reyes
authors.initials: MR
authors.lastname: Lorente Antoñanzas
mesh_terms: D016527:Drug Costs / Q000331:legislation & jurisprudence*; D011307:Drug Prescriptions / Q000706:statistics & numerical data*; D005102:Health Expenditures / Q000331:legislation & jurisprudence* / Q000706:statistics & numerical data; D013030:Spain