title: [The effect of Kaqun-water on the immune parameters of healthy volunteers].
abstract: BACKGROUND
  Kaqun-water contains a high amount of stable oxygen, which absorbed through the skin and intestinal tract, increases tissue oxygenation.
  
  
  OBJECTIVE
  The aim of the authors was to evaluate the effect of 21 days of Kaqun-water treatment on the immune parameters of healthy volunteers.
  
  
  METHODS
  Subpopulations of lymphocytes were determined by immune phenotyping, and CD25 and CD71 activation antigens were used to assess lymphocyte activation. Production of reactive oxygen intermediates was measured to determine the killing capacity of neutrophil granulocytes. Data was analysed with repeated measures ANOVA.
  
  
  RESULTS
  The reactive oxygen intermediate production of neutrophils increased significantly in stimulated samples during three weeks of Kaqun-water treatment. The percent of activated, CD25 positive T and helper T cells, and the ratio of NK cells increased.
  
  
  CONCLUSIONS
  The increase in oxygen concentration caused by Kaqun-water treatment affects several immune functions: the killing potential of neurophil granulocytes is enhanced, the activation of lymphocytes shows an increased activity of immune function, and the elevated ratio of NK cells may help combat virally infected and tumorous cells.
authors.affiliation: Országos Kémiai Biztonsági Intézet Citogenetikai és Immunológiai Csoport Budapest Nagyvárad tér 2. 1096.
authors.forename: Anna
authors.initials: A
authors.lastname: Biró
authors.affiliation: Országos Kémiai Biztonsági Intézet Citogenetikai és Immunológiai Csoport Budapest Nagyvárad tér 2. 1096 Semmelweis Egyetem, Általános Orvostudományi Kar Népegészségtani Intézet Budapest.
authors.forename: Anna
authors.initials: A
authors.lastname: Tompa
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D015703:Antigens, CD / Q000032:analysis; D055612:Cytokine-Induced Killer Cells / Q000276:immunology*; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D016130:Immunophenotyping; D053645:Interleukin-2 Receptor alpha Subunit / Q000032:analysis; D007694:Killer Cells, Natural / Q000276:immunology*; D008213:Lymphocyte Activation / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000628:therapy / Q000821:virology; D009504:Neutrophils / Q000276:immunology*; D010100:Oxygen / Q000008:administration & dosage / Q000276:immunology*; D017382:Reactive Oxygen Species / Q000378:metabolism*; D011990:Receptors, Transferrin / Q000032:analysis; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D014867:Water / Q000008:administration & dosage / Q000737:chemistry*
chemical_list: D015703:Antigens, CD; C068126:CD71 antigen; C508017:IL2RA protein, human; D053645:Interleukin-2 Receptor alpha Subunit; D017382:Reactive Oxygen Species; D011990:Receptors, Transferrin; D014867:Water; D010100:Oxygen
keywords: Kaqun víz; Kaqun-water; NK cell; NK-sejt; immune phenotyping; immunfenotipizálás; leukocyta-ölőképesség; oxidative burst