title: Robustness evaluation of heart rate variability measures for age gender related autonomic changes in healthy volunteers.
abstract: To analyze motion artifact's affect on HRV measures, the age/gender related autonomic changes were investigated by using different HRV measures from wearable medical devices under ambulatory home-monitoring condition. Twelve healthy undergraduates and 20 healthy elderly subjects participated in the research. The electrocardiogram data was collected by using waist-worn device developed by us. Ten HRV measures were used to analyze the age-related automatic change including linear and nonlinear HRV indexes. Many linear HRV indexes were seriously contaminated by motion artefact, and did not reflect the age-related autonomic change. The approximate entropy (p < 0.001) was the best indicator among 10 HRV indexes. However, the approximate entropy was also contaminated by motion artefact and did not reflect the gender-related autonomic change. The study verified the hypothesis that the HRV measures could be contaminated under ambulatory monitoring condition. It is importance for ambulatory home-monitoring to study the robustness of HRV measures.
authors.affiliation: Biomedical Engineering Program, Sun Yat-sen University, Guangzhou, China, yjpn2004@163.com.
authors.forename: Guanzheng
authors.initials: G
authors.lastname: Liu
authors.forename: Qian
authors.initials: Q
authors.lastname: Wang
authors.forename: ShiXiong
authors.initials: S
authors.lastname: Chen
authors.forename: GuangMin
authors.initials: G
authors.lastname: Zhou
authors.forename: WenHui
authors.initials: W
authors.lastname: Chen
authors.forename: YuanYu
authors.initials: Y
authors.lastname: Wu
mesh_terms: D000367:Age Factors; D000368:Aged; D001341:Autonomic Nervous System / Q000502:physiology*; D019277:Entropy; D005260:Female; D064368:Healthy Volunteers; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012727:Sex Characteristics; D013997:Time Factors