title: Insulin pump therapy in transient neonatal diabetes mellitus.
abstract: Neonatal diabetes mellitus (NDM) is a rare disease requiring insulin treatment. Its treatment is primarily focused on maintaining adequate glycemic control and avoiding hypoglycemia. Although insulin pump therapy is frequently administered to adults and children, there is no consensus on the use of insulin pumps in NDM. A 10 day-old female infant was referred to us with intrauterine growth retardation and poor weight gain. Hyperglycemia was noted, and continuous intravenous insulin infusion was initiated. However, the patient's serum glucose levels fluctuated widely, and maintaining the intravenous route became difficult within the following weeks. Continuous subcutaneous insulin infusion with an insulin pump was introduced on the twenty-fifth day of life, and good glycemic control was achieved without any notable adverse effects including hypoglycemia. We suggest that the insulin pump is a safe and effective mode for treating NDM and its early adoption may shorten the length of hospital stays in patients with NDM.
authors.affiliation: Department of Pediatrics, CHA University College of Medicine, Seongnam, Korea.
authors.forename: Joong Heum
authors.initials: JH
authors.lastname: Park
authors.affiliation: Department of Pediatrics, CHA University College of Medicine, Seongnam, Korea.
authors.forename: Jeong Hee
authors.initials: JH
authors.lastname: Kang
authors.affiliation: Department of Pediatrics, CHA University College of Medicine, Seongnam, Korea.
authors.forename: Kyu-Hyung
authors.initials: KH
authors.lastname: Lee
authors.affiliation: Sungae Hospital, Seoul, Korea.
authors.forename: Nam-Hyo
authors.initials: NH
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Han-Wook
authors.initials: HW
authors.lastname: Yoo
authors.affiliation: Department of Pediatrics, Chonbuk National University Medical School, Jeonju, Korea.
authors.forename: Dae-Yeol
authors.initials: DY
authors.lastname: Lee
authors.affiliation: Department of Pediatrics, CHA University College of Medicine, Seongnam, Korea.
authors.forename: Eun-Gyong
authors.initials: EG
authors.lastname: Yoo
keywords: Diabetes mellitus; Insulin infusion systems; Newborn infant