title: Targeting the Achilles' heel of drug-resistant cancer stem cells.
authors.affiliation: Department of Pathology and Moores Cancer Center; University of California, San Diego; La Jolla CA USA.
authors.forename: Laetitia
authors.initials: L
authors.lastname: Seguin
authors.affiliation: Department of Pathology and Moores Cancer Center; University of California, San Diego; La Jolla CA USA.
authors.forename: Maricel
authors.initials: M
authors.lastname: Gozo
authors.affiliation: Department of Pathology and Moores Cancer Center; University of California, San Diego; La Jolla CA USA.
authors.forename: Sara M
authors.initials: SM
authors.lastname: Weis
authors.affiliation: Department of Pathology and Moores Cancer Center; University of California, San Diego; La Jolla CA USA.
authors.forename: David A
authors.initials: DA
authors.lastname: Cheresh
mesh_terms: D000818:Animals; D019008:Drug Resistance, Neoplasm; D066246:ErbB Receptors / Q000037:antagonists & inhibitors*; D005260:Female; D006801:Humans; D039661:Integrin beta3 / Q000378:metabolism*; D008175:Lung Neoplasms / Q000188:drug therapy*; D014411:Neoplastic Stem Cells / Q000187:drug effects*; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use*; D011518:Proto-Oncogene Proteins / Q000378:metabolism*; D020725:ral GTP-Binding Proteins / Q000378:metabolism*; D018631:ras Proteins / Q000378:metabolism*
chemical_list: D039661:Integrin beta3; D047428:Protein Kinase Inhibitors; D011518:Proto-Oncogene Proteins; D066246:ErbB Receptors; D020725:ral GTP-Binding Proteins; D018631:ras Proteins
keywords: EGFR-TKI resistance; KRAS; NFkB; cancer stem cells; integrin β3