title: Choroidal thickness in macular telangiectasia type 2.
abstract: OBJECTIVE
  To assess the choroidal thickness changes in eyes with macular telangiectasia Type 2 and their relationship with the integrity of outer retinal structures and visual acuity.
  
  
  METHODS
  This is a prospective observational study that included 81 eyes (41 subjects) with macular telangiectasia Type 2, including 21 women who underwent enhanced depth choroidal imaging. The choroidal thickness measurements were made at the fovea and at 5 points with an interval of 500 μm in both directions, nasal and temporal from the fovea, and were compared with age-matched healthy subjects. Masked observers assessed the outer retinal structure integrity. Stepwise regression was used to find the relationship between age, spherical equivalent, central macular thickness, integrity of the inner segment/outer segment junction, external limiting membrane integrity, and subfoveal choroidal thickness (SFCT).
  
  
  RESULTS
  The mean age of the subjects was 55.2 ± 7.8 years in study subjects. The mean SFCT was 274.6 ± 45.7 μm. There was no significant difference between the SFCT in eyes with macular telangiectasia Type 2 and age-matched healthy subjects (P = 0.38). There was no correlation between the visual acuity (r = 0.008); integrity of inner segment/outer segment (r = 0.54); external limiting membrane (r = 0.47); central macular thickness (r = 0.31) and SFCT.
  
  
  CONCLUSIONS
  Choroidal thickness did not vary between eyes with macular telangiectasia Type 2 and age-matched healthy subjects. There was no correlation between SFCT and visual acuity, and integrity of the outer retinal structures and central macular thickness.
authors.affiliation: *Smt.Kanuri Santhamma Retina Vitreous Centre, L. V. Prasad Eye Institute, Hyderabad, India; †Division of Vitreoretinal Diseases and Surgery, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; and ‡L. V. Prasad Eye Institute, Kode Venkatadri Chowdary Campus, Vijayawada, India.
authors.forename: Jay
authors.initials: J
authors.lastname: Chhablani
authors.forename: Igor
authors.initials: I
authors.lastname: Kozak
authors.forename: Ganesh Babu
authors.initials: GB
authors.lastname: Jonnadula
authors.forename: Amarnath
authors.initials: A
authors.lastname: Venkata
authors.forename: Raja
authors.initials: R
authors.lastname: Narayanan
authors.forename: Rajeev Reddy
authors.initials: RR
authors.lastname: Pappuru
authors.forename: Podili Srinivas
authors.initials: PS
authors.lastname: Rao
mesh_terms: D000328:Adult; D002829:Choroid / Q000473:pathology*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011446:Prospective Studies; D058456:Retinal Telangiectasis / Q000150:complications* / Q000175:diagnosis; D041623:Tomography, Optical Coherence