title: Mild cognitive impairment diagnosed with the new DSM-5 criteria: prevalence and associations with non-cognitive psychopathology.
abstract: OBJECTIVE
  To contrast the prevalence of mild cognitive impairment (MCI) as diagnosed using DSM-5 criteria (DSM5-MCI) with MCI as diagnosed using Petersen's criteria (P-MCI) and to explore the association of both with non-cognitive psychopathological symptoms (NCPS).
  
  
  METHODS
  A two-phase epidemiological screening was implemented in a population-based sample of individuals aged 55+ (n = 4803). The Geriatric Mental State (GMS) was the main psychopathological instrument used, and AGECAT was used to make psychiatric diagnoses. Research psychiatrists diagnosed DSM5-MCI and P-MCI using operational criteria. Logistic regression models were then used to investigate the association of MCI with anxiety and depression and with NCPS.
  
  
  RESULTS
  Weighted prevalence of DSM5-MCI and P-MCI was, respectively, 3.72% and 7.93% for the aged 65+. NCPS were common in both MCI categories, but negative-type symptoms such as 'anergia' and 'observed slowness' were considerably more frequent among persons with DSM5-MCI. Anxiety and depression diagnostic categories were associated with both P-MCI and DSM5-MCI, but affective-type symptoms were mainly associated with P-MCI. Some negative-type symptoms were inversely associated with P-MCI, and no association was observed with DSM5-MCI.
  
  
  CONCLUSIONS
  The prevalence of DSM5-MCI was half that of P-MCI. Negative-type NCPS were more frequently and typically associated with DSM5-MCI.
authors.affiliation: Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Ministry of Science and Innovation, Madrid, Spain; Department of Psychology and Sociology, Universidad de Zaragoza, Zaragoza, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Lopez-Anton
authors.forename: J
authors.initials: J
authors.lastname: Santabárbara
authors.forename: C
authors.initials: C
authors.lastname: De-la-Cámara
authors.forename: P
authors.initials: P
authors.lastname: Gracia-García
authors.forename: E
authors.initials: E
authors.lastname: Lobo
authors.forename: G
authors.initials: G
authors.lastname: Marcos
authors.forename: G
authors.initials: G
authors.lastname: Pirez
authors.forename: P
authors.initials: P
authors.lastname: Saz
authors.forename: J M
authors.initials: JM
authors.lastname: Haro
authors.forename: L
authors.initials: L
authors.lastname: Rodríguez-Mañas
authors.forename: P J
authors.initials: PJ
authors.lastname: Modrego
authors.forename: M E
authors.initials: ME
authors.lastname: Dewey
authors.forename: A
authors.initials: A
authors.lastname: Lobo
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D060825:Cognitive Dysfunction / Q000175:diagnosis* / Q000453:epidemiology* / Q000523:psychology; D003937:Diagnosis, Differential; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D008875:Middle Aged; D015995:Prevalence; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D013030:Spain / Q000453:epidemiology
keywords: DSM-5; community study; mild cognitive impairment; non-cognitive psychopathological symptoms; prevalence