title: Surgery of the femur in HIV positive patients: a retrospective review from 2005 to 2011.
abstract: BACKGROUND
  There are an estimated 6,900 people with HIV living in Ireland. There is a significant prevalence of femoral osteonecrosis and risk factors for osteoporotic fractures. With this potential, increasing surgical workload, it is important to assess surgical demand and audit outcomes.
  
  
  METHODS
  The hospital's electronic records were examined. Between January 2005 and August 2011, 17 femoral surgeries were identified in seven patients. Patient records were retrospectively reviewed.
  
  
  RESULTS
  Elective operations undertaken were eight hip replacements and one nail dynamisation. Eight emergency operations were undertaken: two DHS, one plating, one nailing, one revision nailing, two incision and drainages and one biopsy. All procedures were carried out using appropriate safety guidelines. Indications for surgery included femoral head osteonecrosis (n = 7), osteomyelitis (n = 3), proximal femoral fracture (n = 2), femoral shaft non-union (n = 1), dynamisation of a nail (n = 1), osteoarthritis (n = 1), fractured femur (n = 1), and revision nailing (n = 1). For two procedures the patient was not on highly active anti-retroviral treatment. All elective patients had CD4 counts greater than 200 pre-operatively. Six patients had undetectable viral loads. Of the eight emergency procedures, four procedures had no preoperative immune status recorded. Complications recorded were three non-unions, one nail fracture, one lesser trochanter fracture and recurrence of osteomyelitis. No surgical site infections were recorded.
  
  
  CONCLUSIONS
  Complications were not related to immune status. The rate of surgical site infection in both elective and emergency procedures was low. The elective surgery patients can safely receive orthopaedic treatment in their regional orthopaedic unit. Due to the high non-infectious complication rates recorded in the emergency group, transfer to a tertiary facility with infectious disease expertise is advised.
authors.affiliation: Departments of Trauma and Orthopaedics, St James's Hospital, Dublin, Ireland, fionnanc@gmail.com.
authors.forename: F
authors.initials: F
authors.lastname: Cummins
authors.forename: B
authors.initials: B
authors.lastname: Ramasubbu
authors.forename: T
authors.initials: T
authors.lastname: McCarthy
authors.forename: C
authors.initials: C
authors.lastname: Bergin
authors.forename: P P
authors.initials: PP
authors.lastname: Grieve
mesh_terms: D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects; D018791:CD4 Lymphocyte Count; D005260:Female; D005264:Femoral Fractures / Q000150:complications / Q000601:surgery*; D005269:Femur; D005271:Femur Head Necrosis / Q000150:complications / Q000601:surgery*; D005594:Fracture Fixation, Intramedullary / Q000009:adverse effects; D005599:Fractures, Ununited / Q000150:complications / Q000601:surgery*; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D007494:Ireland; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000150:complications / Q000601:surgery*; D012189:Retrospective Studies; D019562:Viral Load