title: Highly regio- and stereoselective synthesis of alkylidenecyclopropanes via Ru(II)-Pheox catalyzed asymmetric inter- and intramolecular cyclopropanation of allenes.
abstract: An efficient protocol for the synthesis of optically active alkylidenecyclopropanes (ACPs) via the Ru(II)-Pheox catalyzed asymmetric cyclopropanation of allenes has been established. This catalytic system proceeded with high regioselectivity to give the ACP products in high yield with high diastereoselectivity (up to 99/1) and enantioselectivity (up to 99% ee).
authors.affiliation: Department of Environmental, Life Sciences, Toyohashi University of Technology , 1-1 Hibarigaoka, Tempaku-cho, Toyohashi 441-8580, Japan.
authors.forename: Soda
authors.initials: S
authors.lastname: Chanthamath
authors.forename: Hao Wei
authors.initials: HW
authors.lastname: Chua
authors.forename: Seiya
authors.initials: S
authors.lastname: Kimura
authors.forename: Kazutaka
authors.initials: K
authors.lastname: Shibatomi
authors.forename: Seiji
authors.initials: S
authors.lastname: Iwasa