title: BPA, an energy balance disruptor.
abstract: Bisphenol A (BPA) is used extensively in the world and is present in a diverse range of manufactured articles including dental resins, polycarbonate plastics, and the inner coating of food cans. It is a high volume chemical, with global production at 3.6 × 10(9) kg per year. BPA was identified as a high priority for assessment of human health risk because it was considered to present greatest potential for human exposure. Most studies of the health effects of BPA have focused on endocrine disruption leading to reproductive toxicity, but it displays additional side effects, including liver damage, disrupted pancreatic β-cell function, thyroid hormone disruption, and obesity-promoting effects. In this article, we reviewed specifically on the effects of BPA in energy balance.
authors.affiliation: a Laboratoire de Toxicologie Alimentaire, INSERM U866, NUTOX, Derttech Packtox , University of Burgundy , Dijon , France.
authors.forename: L
authors.initials: L
authors.lastname: Le Corre
authors.forename: P
authors.initials: P
authors.lastname: Besnard
authors.forename: M-C
authors.initials: MC
authors.lastname: Chagnon
mesh_terms: D000818:Animals; D001559:Benzhydryl Compounds / Q000009:adverse effects*; D052244:Endocrine Disruptors / Q000009:adverse effects*; D004734:Energy Metabolism / Q000187:drug effects*; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D010636:Phenols / Q000009:adverse effects*; D051381:Rats; D015430:Weight Gain / Q000187:drug effects; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D052244:Endocrine Disruptors; D010636:Phenols; C006780:bisphenol A; D000098826:Bisphenol A Compounds
keywords: Bisphenol A; endocrine disruptor; lipid and glucose homeostasis; obesogens; toxic chemical