title: Improved total variation minimization method for few-view computed tomography image reconstruction.
abstract: BACKGROUND
  Due to the harmful radiation dose effects for patients, minimizing the x-ray exposure risk has been an area of active research in medical computed tomography (CT) imaging. In CT, reducing the number of projection views is an effective means for reducing dose. The use of fewer projection views can also lead to a reduced imaging time and minimizing potential motion artifacts. However, conventional CT image reconstruction methods will appears prominent streak artifacts for few-view data. Inspired by the compressive sampling (CS) theory, iterative CT reconstruction algorithms have been developed and generated impressive results.
  
  
  METHODS
  In this paper, we propose a few-view adaptive prior image total variation (API-TV) algorithm for CT image reconstruction. The prior image reconstructed by a conventional analytic algorithm such as filtered backprojection (FBP) algorithm from densely angular-sampled projections.
  
  
  RESULTS
  To validate and evaluate the performance of the proposed algorithm, we carried out quantitative evaluation studies in computer simulation and physical experiment.
  
  
  CONCLUSIONS
  The results show that the API-TV algorithm can yield images with quality comparable to that obtained with existing algorithms.
authors.affiliation: Paul Lauterbur Center for Biomedical Imaging Research, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China. zl.hu@siat.ac.cn.
authors.forename: Zhanli
authors.initials: Z
authors.lastname: Hu
authors.forename: Hairong
authors.initials: H
authors.lastname: Zheng
mesh_terms: D000465:Algorithms; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed / Q000379:methods*; D055114:X-Ray Microtomography