title: Brugada syndrome and idiopathic left ventricular tachycardia unmasked by exercise and a class Ic drug.
abstract: The patient was a 33-year-old male. Twenty years ago, he underwent radiofrequency catheter ablation for idiopathic sustained monomorphic ventricular tachycardia (VT) with an RBBB and superior axis pattern. The VT was inducible by programmed stimulation and entrained by rapid pacing. At this presentation, he developed palpitation and VT with the same morphology at the peak exercise on a treadmill with appearance of typical ECG pattern for Brugada syndrome (BrS). Pilsicainide induced the typical ECG pattern and premature ventricular beats (PVBs) of the same morphology as VT. The relationship between BrS and VT of left ventricular origin was discussed.
authors.affiliation: Tachikawa General Hospital, Cardiology, Nagaoka, Japan.
authors.forename: Sho
authors.initials: S
authors.lastname: Yuasa
authors.affiliation: Tachikawa General Hospital, Cardiology, Nagaoka, Japan.
authors.forename: Masahito
authors.initials: M
authors.lastname: Sato
authors.affiliation: Tachikawa General Hospital, Cardiology, Nagaoka, Japan.
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Kitazawa
authors.affiliation: Tachikawa General Hospital, Cardiology, Nagaoka, Japan.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Okabe
authors.affiliation: Tachikawa General Hospital, Cardiology, Nagaoka, Japan.
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Komatsu
authors.affiliation: Tachikawa General Hospital, Cardiology, Nagaoka, Japan.
authors.forename: Tomoyasu
authors.initials: T
authors.lastname: Koshikawa
authors.affiliation: Miyajima Clinics, Tsubame, Japan.
authors.forename: Seiichi
authors.initials: S
authors.lastname: Miyajima
authors.affiliation: Tachikawa Medical Center, Research and Development, Nagaoka, Japan. Electronic address: aizaways@med.niigata-u.ac.jp.
authors.forename: Yoshifusa
authors.initials: Y
authors.lastname: Aizawa
mesh_terms: D000328:Adult; D000889:Anti-Arrhythmia Agents; D053840:Brugada Syndrome / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D006328:Cardiac Catheterization; D017147:Defibrillators, Implantable; D004562:Electrocardiography; D005080:Exercise Test; D006801:Humans; D008012:Lidocaine / Q000031:analogs & derivatives*; D008297:Male; D017180:Tachycardia, Ventricular / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy
chemical_list: D000889:Anti-Arrhythmia Agents; D008012:Lidocaine; C042288:pilsicainide
keywords: Brugada syndrome; Exercise; Pilsicainide; Ventricular tachycardia