title: Role of molecular properties of ulvans on their ability to elaborate antiadhesive surfaces.
abstract: Antiadhesive properties of polysaccharides (such ulvans) once immobilized on a surface are described in the literature but the parameters governing their antifouling properties are not yet well identified. In the present study, the relationship between molecular parameters of ulvans and the inhibition of bacterial adhesion was investigated. To this aim, various ulvans were grafted on silicon wafers under two different experimental immobilization conditions. Results showed that the experimental immobilization conditions and the polysaccharides molecular weight led to specific layer conformations which exhibited a key role in the surface antiadhesive properties.
authors.affiliation: CNRS, UMR 6270, Polymères, Biopolymères, Surfaces Laboratory, F-76821 Mont-Saint-Aignan, France; Normandie Univ, UR, France.
authors.forename: Virginie
authors.initials: V
authors.lastname: Gadenne
authors.forename: Laurent
authors.initials: L
authors.lastname: Lebrun
authors.forename: Thierry
authors.initials: T
authors.lastname: Jouenne
authors.forename: Pascal
authors.initials: P
authors.lastname: Thebault
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry*; D001422:Bacterial Adhesion; D001672:Biocompatible Materials / Q000737:chemistry*; D018441:Biofilms; D002448:Cell Adhesion; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D008422:Materials Testing; D008826:Microbial Sensitivity Tests; D008970:Molecular Weight; D011134:Polysaccharides / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared; D013211:Staphylococcus aureus; D013499:Surface Properties
chemical_list: D000890:Anti-Infective Agents; D001672:Biocompatible Materials; D020099:Coated Materials, Biocompatible; D011134:Polysaccharides; D012997:Solvents; C571831:ulvan
keywords: Staphylococcus aureus; adhesion; biofilms; polysaccharides