title: Father-son chats: inheriting stress through sperm RNA.
abstract: Although mounting evidence in mammals suggests that certain ancestral environmental exposures can influence the phenotype in future generations, mechanisms underlying such intergenerational information transfer remain unclear. A recent report suggests that RNA isolated from sperm can inform offspring of a father's history of early life trauma (Gapp et al., 2014).
authors.affiliation: Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
authors.forename: Upasna
authors.initials: U
authors.lastname: Sharma
authors.affiliation: Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address: oliver.rando@umassmed.edu.
authors.forename: Oliver J
authors.initials: OJ
authors.lastname: Rando
mesh_terms: D000818:Animals; D005260:Female; D008297:Male; D035683:MicroRNAs / Q000378:metabolism*; D013094:Spermatozoa; D013315:Stress, Psychological / Q000209:etiology* / Q000628:therapy*
chemical_list: D035683:MicroRNAs