title: Trichoderma species fungemia after high-dose chemotherapy and autologous stem cell transplantation: a case report.
abstract: We present a case of Trichoderma fungemia with pulmonary involvement in a multiple myeloma patient, who was severely immunocompromised and heavily treated with high-dose melphalan, and underwent autologous hematopoietic cell transplantation. This is the first report, to our knowledge, of proven Trichoderma fungemia, defined by published criteria, successfully treated with voriconazole.
authors.affiliation: Division of Hematology of the University of Torino, Azienda Ospedaliera Città della Salute e della Scienza di Torino, Torino, Italy; Dipartimento di Biotecnologie Molecolari e Scienze per la Salute, University of Torino, Torino, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Festuccia
authors.forename: L
authors.initials: L
authors.lastname: Giaccone
authors.forename: F
authors.initials: F
authors.lastname: Gay
authors.forename: L
authors.initials: L
authors.lastname: Brunello
authors.forename: E
authors.initials: E
authors.lastname: Maffini
authors.forename: F
authors.initials: F
authors.lastname: Ferrando
authors.forename: E
authors.initials: E
authors.lastname: Talamo
authors.forename: M
authors.initials: M
authors.lastname: Boccadoro
authors.forename: R
authors.initials: R
authors.lastname: Serra
authors.forename: A
authors.initials: A
authors.lastname: Barbui
authors.forename: B
authors.initials: B
authors.lastname: Bruno
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D016469:Fungemia / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology*; D033581:Stem Cell Transplantation / Q000009:adverse effects*; D014242:Trichoderma / Q000145:classification / Q000302:isolation & purification*; D065819:Voriconazole / Q000627:therapeutic use
chemical_list: D000935:Antifungal Agents; D000970:Antineoplastic Agents; D065819:Voriconazole
keywords: Trichoderma; autologous transplant; fungemia