title: aglgenes, A curated and searchable database of archaeal N-glycosylation pathway components.
abstract: Whereas N-glycosylation is a posttranslational modification performed across evolution, the archaeal version of this protein-processing event presents a degree of diversity not seen in either bacteria or eukarya. Accordingly, archaeal N-glycosylation relies on a large number of enzymes that are often species-specific or restricted to a select group of species. As such, there is a need for an organized platform upon which amassing information about archaeal glycosylation (agl) genes can rest. Accordingly, the aglgenes database provides detailed descriptions of experimentally characterized archaeal N-glycosyation pathway components. For each agl gene, genomic information, supporting literature and relevant external links are provided at a functional intuitive web-interface designed for data browsing. Routine updates ensure that novel experimental information on genes and proteins contributing to archaeal N-glycosylation is incorporated into aglgenes in a timely manner. As such, aglgenes represents a specialized resource for sharing validated experimental information online, providing support for workers in the field of archaeal protein glycosylation. Database URL: www.bgu.ac.il/aglgenes.
authors.affiliation: Department of Life Sciences, Ben Gurion University of the Negev, P.O. Box 653, Beersheva 84105, Israel.
authors.forename: Noa
authors.initials: N
authors.lastname: Godin
authors.affiliation: Department of Life Sciences, Ben Gurion University of the Negev, P.O. Box 653, Beersheva 84105, Israel jeichler@bgu.ac.il.
authors.forename: Jerry
authors.initials: J
authors.lastname: Eichler
mesh_terms: D001105:Archaea / Q000235:genetics* / Q000378:metabolism*; D019843:Archaeal Proteins / Q000378:metabolism*; D057225:Data Mining; D030541:Databases, Genetic; D030562:Databases, Protein; D019766:Genes, Archaeal; D006031:Glycosylation; D058977:Molecular Sequence Annotation; D057386:Search Engine; D012984:Software
chemical_list: D019843:Archaeal Proteins