title: Giant Cell Tumor Pulmonary Metastases Mimic Primary Malignant Pulmonary Nodules on (18)F-FDG PET/CT.
abstract: A 59-year-old man with a 30-year history of multiple recurrences of a giant cell tumor (GCT) of the left knee was referred for an (18)F-FDG PET/CT to evaluate a solitary pulmonary nodule. The nodule was mildly FDG-avid, raising suspicion of malignancy. It was excised and histologically proven to be a GCT pulmonary metastasis. A follow-up PET/CT done 2 years later revealed a new, larger lung mass that was more intensely FDG-avid, but of the same histology. This rare report highlights a pitfall in the evaluation of solitary pulmonary lesions by (18)F-FDG PET/CT in patients with GCT of the bone.
authors.affiliation: Department of Nuclear Medicine, Brandon Regional Health Centre, 150 McTavish Ave E, Brandon, MB R7A 2B3 Canada.
authors.forename: William
authors.initials: W
authors.lastname: Makis
authors.affiliation: Department of Nuclear Medicine, Royal Victoria Hospital, McGill University Health Centre, 687 Pine Ave West, M2, Montreal, QC H3A 1A1 Canada.
authors.forename: Yazan Z
authors.initials: YZ
authors.lastname: Alabed
authors.affiliation: Department of Pathology, Montreal General Hospital, McGill University Health Centre, 1650 Avenue Cedar, D3-257, Montreal, QC H3G 1A4 Canada.
authors.forename: Ayoub
authors.initials: A
authors.lastname: Nahal
authors.affiliation: Department of Nuclear Medicine, Royal Victoria Hospital, McGill University Health Centre, 687 Pine Ave West, M2, Montreal, QC H3A 1A1 Canada.
authors.forename: Javier A
authors.initials: JA
authors.lastname: Novales-Diaz
authors.affiliation: Department of Nuclear Medicine, Royal Victoria Hospital, McGill University Health Centre, 687 Pine Ave West, M2, Montreal, QC H3A 1A1 Canada.
authors.forename: Marc
authors.initials: M
authors.lastname: Hickeson
keywords: FDG; GCT; Giant cell tumor; PET/CT; Pulmonary metastases