title: Bacillus licheniformis isolated from Korean traditional food sources enhances the resistance of Caenorhabditis elegans to infection by Staphylococcus aureus.
abstract: We investigated whether Bacillus spp., newly isolated from Korean traditional food resources, influence the resistance of hosts to foodborne pathogens, by using Caenorhabditis elegans as a surrogate host model. Initially, we selected 20 Bacillus spp. that possess antimicrobial activity against various foodborne pathogens, including Staphylococcus aureus. Among the selected strains, six strains of Bacillus spp. used in preconditioning significantly prolonged the survival of nematodes exposed to S. aureus. Based on 16S rRNA gene sequencing, all six strains were identified as B. licheniformis. Our findings suggest that preconditioning with B. licheniformis may modulate the host defense response against S. aureus.
authors.affiliation: BK21 Plus Graduate Program, Department of Animal Science, Chonbuk National University, Jeonju 561-756, Republic of Korea.
authors.forename: Hyun Sun
authors.initials: HS
authors.lastname: Yun
authors.forename: Ju Hee
authors.initials: JH
authors.lastname: Heo
authors.forename: Seok Jun
authors.initials: SJ
authors.lastname: Son
authors.forename: Mi Ri
authors.initials: MR
authors.lastname: Park
authors.forename: Sangnam
authors.initials: S
authors.lastname: Oh
authors.forename: Min-Ho
authors.initials: MH
authors.lastname: Song
authors.forename: Jong Nam
authors.initials: JN
authors.lastname: Kim
authors.forename: Gwang-Woong
authors.initials: GW
authors.lastname: Go
authors.forename: Ho-Seong
authors.initials: HS
authors.lastname: Cho
authors.forename: Nag-Jin
authors.initials: NJ
authors.lastname: Choi
authors.forename: Seung-Wha
authors.initials: SW
authors.lastname: Jo
authors.forename: Do-Youn
authors.initials: DY
authors.lastname: Jeong
authors.forename: Younghoon
authors.initials: Y
authors.lastname: Kim
mesh_terms: D000818:Animals; D000898:Antibiosis; D001407:Bacillus / Q000145:classification / Q000302:isolation & purification*; D017173:Caenorhabditis elegans / Q000382:microbiology* / Q000502:physiology*; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D004195:Disease Models, Animal; D060467:Disease Resistance; D005516:Food Microbiology; D007723:Korea; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA; D013203:Staphylococcal Infections / Q000276:immunology*; D013211:Staphylococcus aureus; D016019:Survival Analysis
chemical_list: D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S