title: Uncommon associations and catastrophic manifestation in Takayasu arteritis: an autopsy case report.
abstract: Takayasu arteritis, a chronic inflammatory vasculitis affecting aorta and its major branches, is complicated by stenosis, occlusion, and aneurysm formation. The aneurysm formation and subsequent complications such as heart failure, aortic regurgitation, and aneurysm rupture can be fatal. The aortic aneurysm rupture is a rare and fatal complication with only a few cases reported in the English literature. The involvement of coronary artery in Takayasu occurs in about 10% patients, and the coronary artery aneurysm is the least common manifestation. Here, we describe a case of Takayasu arteritis with abdominal aortic aneurysm rupture and coronary artery aneurysm. This patient also had associated systemic inflammatory diseases like sarcoidosis and Hashimoto's thyroiditis.
authors.affiliation: Department of Histopathology, Post Graduate Institute of Medical Education & Research, (PGIMER), Sector - 12, Chandigarh- 160012, India.
authors.forename: Abhijit
authors.initials: A
authors.lastname: Chougule
authors.affiliation: Department of Histopathology, Post Graduate Institute of Medical Education & Research, (PGIMER), Sector - 12, Chandigarh- 160012, India. Electronic address: docaman5@hotmail.com.
authors.forename: Amanjit
authors.initials: A
authors.lastname: Bal
authors.affiliation: Department of Histopathology, Post Graduate Institute of Medical Education & Research, (PGIMER), Sector - 12, Chandigarh- 160012, India.
authors.forename: Ashim
authors.initials: A
authors.lastname: Das
authors.affiliation: Department of Internal Medicine, Post Graduate Institute of Medical Education & Research, (PGIMER), Sector - 12, Chandigarh- 160012, India.
authors.forename: Sanjay
authors.initials: S
authors.lastname: Jain
authors.affiliation: Department of Cardiology, Post Graduate Institute of Medical Education & Research, (PGIMER), Sector - 12, Chandigarh- 160012, India.
authors.forename: Ajay
authors.initials: A
authors.lastname: Bahl
mesh_terms: D000328:Adult; D017668:Age of Onset; D017544:Aortic Aneurysm, Abdominal / Q000209:etiology / Q000473:pathology; D001019:Aortic Rupture / Q000209:etiology / Q000473:pathology; D001344:Autopsy; D003323:Coronary Aneurysm / Q000209:etiology / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D013625:Takayasu Arteritis / Q000150:complications* / Q000473:pathology*; D055815:Young Adult
keywords: Aneurysm; Coronary; Rupture; Sarcoidosis; Takayasu arteritis