title: Chiral ionic liquids in chromatographic and electrophoretic separations.
abstract: This report provides an overview of the application of chiral ionic liquids (CILs) in separation technology, and particularly in capillary electrophoresis and both gas and liquid chromatography. There is a large number of CILs that have been synthesized and designed as chiral agents. However, only a few have successfully been applied in separation technology. Even though this application of CILs is still in its early stages, the scientific interest is increasing dramatically. This article is focused on the use of CILs as chiral selectors, background electrolyte additives, chiral ligands and chiral stationary phases in electrophoretic and chromatographic techniques. Different examples of CILs, which contain either a chiral cation, a chiral anion or both, are presented in this review article, and their major advantages along with their potential applications in chiral electrophoretic and chromatographic recognition are discussed.
authors.affiliation: Department of Chemistry, University of Cyprus, 1678 Nicosia, Cyprus. Electronic address: ckapni1@ucy.ac.cy.
authors.forename: Constantina P
authors.initials: CP
authors.lastname: Kapnissi-Christodoulou
authors.affiliation: Department of Chemistry, University of Cyprus, 1678 Nicosia, Cyprus.
authors.forename: Ioannis J
authors.initials: IJ
authors.lastname: Stavrou
authors.affiliation: Department of Chemistry, University of Cyprus, 1678 Nicosia, Cyprus.
authors.forename: Maria C
authors.initials: MC
authors.lastname: Mavroudi
mesh_terms: D002849:Chromatography, Gas / Q000379:methods*; D002853:Chromatography, Liquid / Q000379:methods*; D019075:Electrophoresis, Capillary / Q000379:methods*; D052578:Ionic Liquids / Q000737:chemistry*; D008024:Ligands; D013237:Stereoisomerism
chemical_list: D052578:Ionic Liquids; D008024:Ligands
keywords: Capillary electrophoresis; Chiral ionic liquids; Chiral separations; Chromatography; Ionic liquids; Review