title: Symptom severity and conservative treatment for carpal tunnel syndrome in association with eventual carpal tunnel release.
abstract: OBJECTIVE
  To study the relationship between the severity of carpal tunnel syndrome (CTS) symptoms and surgery for CTS and the relationship between conservative treatments and surgery for CTS.
  
  
  METHODS
  A secondary analysis of baseline to 6-month data from a randomized controlled trial, which examined the effectiveness of orthosis/stretch combinations on the symptoms of CTS, was conducted for a total of 96 participants with CTS. Participants completed the Carpal Tunnel Questionnaire and posttreatment surveys. Statistical analyses included exploration of correlates of progression to surgery for CTS and logistical regression to examine the association between conservative treatments and CTS symptoms and progression to surgery for CTS.
  
  
  RESULTS
  Twenty-one participants received surgery for their CTS, and 31 participants received 1 or more conservative treatments. Severity of baseline CTS symptoms and additional treatments were indicators of progression to surgery. The randomized controlled trial intervention was inversely associated with progression to surgery.
  
  
  CONCLUSIONS
  CTS that does not respond to an initial course of conservative treatment may not improve with additional treatments. More than half of the participants who received additional conservative treatment still progressed to surgery. Current intervention guidelines for CTS provide limited guidance as to the best methods to efficiently treat CTS.
  
  
  CONCLUSIONS
  CTS is a costly and high-burden disorder, resulting in reduced quality of life. Research should examine when and for whom conservative care is an effective choice and the association between conservative care and the eventual need for CTS surgery.
authors.affiliation: Department of Occupational Therapy, University of Pittsburgh, School of Health and Rehabilitation Sciences, Pittsburgh, PA.
authors.forename: Nancy A
authors.initials: NA
authors.lastname: Baker
authors.affiliation: Department of Occupational Therapy, University of Pittsburgh, School of Health and Rehabilitation Sciences, Pittsburgh, PA. Electronic address: hml12@pitt.edu.
authors.forename: Heather M
authors.initials: HM
authors.lastname: Livengood
mesh_terms: D002349:Carpal Tunnel Syndrome / Q000601:surgery / Q000628:therapy*; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D052580:Muscle Stretching Exercises; D009989:Orthotic Devices; D018579:Patient Selection; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
keywords: Carpal tunnel syndrome; carpal tunnel release surgery; rehabilitation; treatment