title: Clinical efficacy of low-level laser therapy on localized canine atopic dermatitis severity score and localized pruritic visual analog score in pedal pruritus due to canine atopic dermatitis.
abstract: BACKGROUND
  Canine atopic dermatitis is a genetically predisposed inflammatory skin disease often requiring multimodal treatment. There is a need to find further low-risk adjunctive therapies.
  
  
  OBJECTIVE
  To evaluate the localized effect of low-level laser therapy (LLLT) on the paws of dogs with atopic dermatitis using a localized canine atopic dermatitis severity score (LCADSS) and owner localized pruritic visual analog score (LPVAS) in comparison to treatment with a placebo.
  
  
  METHODS
  Thirty client-owned dogs with symmetrical pedal pruritus due to canine atopic dermatitis.
  
  
  METHODS
  Dogs were randomly assigned into two groups. In each group, one paw was treated with LLLT and one paw treated with a placebo laser (comparing either both fore- or hindpaws). Treatments were administered at 4 J/cm(2) (area from carpus/tarsus to distal aspect of digit 3) three times per week for the first 2 weeks and two times per week for the second 2 weeks. Scores were assessed for each paw at weeks 0, 2, 4 and 5.
  
  
  RESULTS
  There were no significant differences in LCADSS or LPVAS between LLLT and placebo treatments between weeks 0 and 5 (P = 0.0856 and 0.5017, respectively). However, LCADSS and LPVAS significantly decreased from week 0 at weeks 2, 4 and 5 in both LLLT and placebo groups (P < 0.0001 for all).
  
  
  CONCLUSIONS
  Low-level laser therapy is not an effective localized treatment for pedal pruritus in canine atopic dermatitis.
authors.affiliation: Animal Dermatology Clinic, 2965 Edinger Avenue, Tustin, CA, 92780, USA.
authors.forename: Ashley N
authors.initials: AN
authors.lastname: Stich
authors.forename: Wayne S
authors.initials: WS
authors.lastname: Rosenkrantz
authors.forename: Craig E
authors.initials: CE
authors.lastname: Griffin
mesh_terms: D000818:Animals; D003876:Dermatitis, Atopic / Q000150:complications / Q000532:radiotherapy / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis / Q000532:radiotherapy*; D004285:Dogs; D005260:Female; D005533:Foot Dermatoses / Q000532:radiotherapy / Q000662:veterinary*; D028022:Low-Level Light Therapy / Q000379:methods / Q000662:veterinary*; D008297:Male; D011537:Pruritus / Q000175:diagnosis / Q000209:etiology / Q000662:veterinary*; D012720:Severity of Illness Index; D016896:Treatment Outcome; D064232:Visual Analog Scale