title: Diffuse alveolar haemorrhage and severe hypoxemia from Strongyloides stercoralis hyperinfection syndrome.
abstract: Strongyloides stercoralis hyperinfection syndrome is a rare, yet highly fatal disorder. It occurs most commonly in immunocompromised patients. We report a case of a 36-year-old Ethiopian female who presented with abdominal pain and hypotension. Shortly thereafter, she developed acute respiratory failure and progressed to acute respiratory distress syndrome and septic shock. She was found to have diffuse alveolar hemorrhage due to disseminated strongyloidiasis. We discuss the clinical condition of Strongyloides hyperinfection syndrome presenting with severe hypoxemia and complicated by severe diffuse alveolar hemorrhage leading to death. Similar cases in the literature are also describe.
authors.affiliation: Respirology Division, Medicine Institute, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.
authors.forename: Yaser Abu
authors.initials: YA
authors.lastname: El-Sameed
authors.affiliation: Gastroenterology Division, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.
authors.forename: Nigel
authors.initials: N
authors.lastname: Beejay
authors.affiliation: Respirology Division, Medicine Institute, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.
authors.forename: Rehab
authors.initials: R
authors.lastname: Al Maashari
mesh_terms: D000328:Adult; D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D005260:Female; D006470:Hemorrhage / Q000188:drug therapy / Q000469:parasitology*; D006801:Humans; D007559:Ivermectin / Q000627:therapeutic use; D011650:Pulmonary Alveoli / Q000469:parasitology*; D012131:Respiratory Insufficiency / Q000188:drug therapy / Q000469:parasitology*; D017171:Strongyloides stercoralis / Q000302:isolation & purification*; D013322:Strongyloidiasis / Q000150:complications* / Q000188:drug therapy
chemical_list: D000871:Anthelmintics; D007559:Ivermectin; D015766:Albendazole
keywords: diffuse alveolar hemorrhage; hyperinfection syndrome; severe hypoxemia; strongyloides stercoralis