title: Using (18)F-FDG PET/CT to Detect an Occult Mesenchymal Tumor Causing Oncogenic Osteomalacia.
abstract: Oncogenic osteomalacia is a rare paraneoplastic syndrome characterized by renal phosphate excretion, hypophosphatemia, and osteomalacia. This syndrome is often caused by tumors of mesenchymal origin. Patients with oncogenic osteomalacia have abnormal bone mineralization, resulting in a high frequency of fractures. Tumor resection is the treatment of choice, as it will often correct the metabolic imbalance. Although oncogenic osteomalacia is a potentially curable disease, diagnosis is difficult and often delayed because of the small size and sporadic location of the tumor. Bone scintigraphy and radiography best characterize osteomalacia; magnetic resonance imaging findings are nonspecific. Here, we report a case of oncogenic osteomalacia secondary to a phosphaturic mesenchymal tumor that was successfully detected by (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT). This case illustrates the advantages of (18)F-FDG PET/CT in detecting the occult mesenchymal tumor that causes oncogenic osteomalacia.
authors.affiliation: Division of Nuclear Medicine, Department of Radiology, Yonsei University College of Medicine, Seongsanno 250, Seodaemun-gu, Seoul, 120-752 Korea.
authors.forename: Hyo Jung
authors.initials: HJ
authors.lastname: Seo
authors.affiliation: Division of Nuclear Medicine, Department of Radiology, Yonsei University College of Medicine, Seongsanno 250, Seodaemun-gu, Seoul, 120-752 Korea.
authors.forename: Yun Jung
authors.initials: YJ
authors.lastname: Choi
authors.affiliation: Division of Nuclear Medicine, Department of Radiology, Yonsei University College of Medicine, Seongsanno 250, Seodaemun-gu, Seoul, 120-752 Korea.
authors.forename: Hyun Jeong
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Division of Nuclear Medicine, Department of Radiology, Yonsei University College of Medicine, Seongsanno 250, Seodaemun-gu, Seoul, 120-752 Korea.
authors.forename: Yong Hyu
authors.initials: YH
authors.lastname: Jeong
authors.affiliation: Division of Nuclear Medicine, Department of Radiology, Yonsei University College of Medicine, Seongsanno 250, Seodaemun-gu, Seoul, 120-752 Korea.
authors.forename: Arthur
authors.initials: A
authors.lastname: Cho
authors.affiliation: Division of Nuclear Medicine, Department of Radiology, Yonsei University College of Medicine, Seongsanno 250, Seodaemun-gu, Seoul, 120-752 Korea.
authors.forename: Jae Hoon
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Division of Nuclear Medicine, Department of Radiology, Yonsei University College of Medicine, Seongsanno 250, Seodaemun-gu, Seoul, 120-752 Korea.
authors.forename: Mijin
authors.initials: M
authors.lastname: Yun
authors.affiliation: Division of Nuclear Medicine, Department of Radiology, Yonsei University College of Medicine, Seongsanno 250, Seodaemun-gu, Seoul, 120-752 Korea.
authors.forename: Jong Doo
authors.initials: JD
authors.lastname: Lee
authors.affiliation: Division of Nuclear Medicine, Department of Radiology, Yonsei University College of Medicine, Seongsanno 250, Seodaemun-gu, Seoul, 120-752 Korea.
authors.forename: Won Jun
authors.initials: WJ
authors.lastname: Kang
keywords: 18F-fluorodeoxyglucose; Oncogenic osteomalacia; Positron emission tomography