title: Is it safe to perform joint infiltrations or aspirations in patients anticoagulated with acenocoumarol?
abstract: The purpose of this study is to determine the rate of bleeding complications in patient's anticoagulated with acenocoumarol according to the international normalized ratio (INR) coagulation index. A cross-sectional study was performed with 901 charts of patients who underwent arthrocentesis or joint infiltration between 2009 and 2013; the charts were grouped on the basis of having an INR higher or lower than 2.0 (268 and 633, respectively). Comparisons were performed in terms of rates of early or late bleeding complications. A 0.37% rate of early bleeding complications (< 24hours) was observed in the group of patients with INR<2 and 0.99% in the group of patients with INR≥2 (P=.47). Only one case of late complication was presented by bleeding between 24 hours and 30 days, in the group of patients with INR≥2. We conclude that oral anticoagulation with acenocoumarol at terapeutical doses does not increase the risk of bleeding joint punctures.
authors.affiliation: Servicio de Reumatología, Hospital Universitario Ramón y Cajal, Madrid, España; Consulta de Urgencias Reumatológicas y Musculoesqueléticas, Servicio de Urgencias, Hospital Universitario Ramón y Cajal, Madrid, España; Servicio de Urgencias, Hospital Universitario Ramón y Cajal, Madrid, España. Electronic address: caranguillen@gmail.com.
authors.forename: Carlos
authors.initials: C
authors.lastname: Guillen Astete
authors.affiliation: Servicio de Reumatología, Hospital Universitario Ramón y Cajal, Madrid, España; Consulta de Urgencias Reumatológicas y Musculoesqueléticas, Servicio de Urgencias, Hospital Universitario Ramón y Cajal, Madrid, España; Servicio de Urgencias, Hospital Universitario Ramón y Cajal, Madrid, España.
authors.forename: Alina
authors.initials: A
authors.lastname: Boteanu
authors.affiliation: Servicio de Reumatología, Hospital Universitario Ramón y Cajal, Madrid, España.
authors.forename: Carmen
authors.initials: C
authors.lastname: Medina Quiñones
authors.affiliation: Servicio de Urgencias, Hospital Universitario Ramón y Cajal, Madrid, España.
authors.forename: Nuria
authors.initials: N
authors.lastname: Garcia Montes
authors.affiliation: Servicio de Urgencias, Hospital Universitario Ramón y Cajal, Madrid, España.
authors.forename: Fernando
authors.initials: F
authors.lastname: Roldan Moll
authors.affiliation: Servicio de Urgencias, Hospital Universitario Ramón y Cajal, Madrid, España.
authors.forename: César
authors.initials: C
authors.lastname: Carballo Carmano
authors.affiliation: Servicio de Reumatología, Hospital Universitario Ramón y Cajal, Madrid, España.
authors.forename: Antonio
authors.initials: A
authors.lastname: Zea Mendoza
mesh_terms: D000074:Acenocoumarol / Q000009:adverse effects*; D000284:Administration, Oral; D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects*; D000069237:Arthrocentesis / Q000009:adverse effects*; D003430:Cross-Sectional Studies; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced* / Q000209:etiology; D006801:Humans; D007270:Injections, Intra-Articular; D019934:International Normalized Ratio; D007592:Joint Diseases / Q000139:chemically induced* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D000925:Anticoagulants; D000074:Acenocoumarol
keywords: Acenocoumarol; Acenocumarol; Anticoagulación; Anticoagulation; Arthrocentesis; Artrocentesis; Infiltración articular; Joint injection