title: [A very rare cause of haemoptysis - coexistence of primary oncocytic adenoma of trachea with bronchial carcinoma].
abstract: METHODS
  A 70-year-old man with a past history of COPD stage GOLD D with home oxygen therapy and tracheotomy due to long-term ventilation (898 hours) 6 years ago was admitted for investigation of haemoptysis during oral anticoagulation. He suffered from peripheral arterial disease (PAD) with bypass and repeated thrombectomy due to recurrent bypass caps, despite effective warfarin therapy. He had all cardiovascular risk factors.
  
  
  METHODS
  The suspicion of a bronchial carcinoma was confirmed by CT. Bronchoscopically a 2 cm lesion in the left upper lobe was biopsied. Additionally, bronchoscopy revealed an approximately erythematous, bloody discolored lesion (diameter 7 mm) at a tracheotomy scar.
  
  
  METHODS
  The biopsies revealed an adenocarcinoma in the left upper lobe and an oncocytic adenoma of the trachea - an extremely rare adenoma. The staging result was cT1b cN0 cM0 G2 IASLC Ia. Because of his severe multiple diseases the patient was in an inoperable condition. An interdisciplinary tumor conference recommended an individualized approach with a definitive radiotherapy of the adenocarcinoma. Endoscopic control of the macroscopically completely removed oncocytic adenoma of the trachea shall be performed one year later.
  
  
  CONCLUSIONS
  Oncocytoma is an extremely rare adenoma (of the trachea), which in this case, has caused haemoptysis in addition to lung cancer during anticoagulation. For tumor genesis a reactive or hyperplasic response after tracheotomy 6 years ago is considered. Resection is the treatment of choice because of the potential for infiltrative growth. But the decision to treat always depends on individual benefit.
authors.affiliation: Medizinische Klinik für Gastroenterologie, Marien-Hospital Euskirchen.
authors.forename: Y
authors.initials: Y
authors.lastname: Vogel
authors.affiliation: Medizinische Klinik für Gastroenterologie, Marien-Hospital Euskirchen.
authors.forename: I
authors.initials: I
authors.lastname: Wolff
authors.affiliation: Institut für Pathologie, Bonn-Duisdorf.
authors.forename: T
authors.initials: T
authors.lastname: Zienkiewicz
authors.affiliation: Institut für Pathologie der Universität Köln.
authors.forename: R
authors.initials: R
authors.lastname: Büttner
authors.affiliation: Medizinische Klinik für Pneumologie, Kardiologie und Allergologie, Malteserkrankenhaus Bonn.
authors.forename: W
authors.initials: W
authors.lastname: Schulte
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D018249:Adenoma, Oxyphilic / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D000368:Aged; D001706:Biopsy; D001999:Bronchoscopy; D015897:Comorbidity; D003299:Cooperative Behavior; D006305:Health Status Indicators; D006469:Hemoptysis / Q000097:blood / Q000209:etiology* / Q000473:pathology; D006801:Humans; D033183:Interdisciplinary Communication; D019934:International Normalized Ratio; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D008297:Male; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D010166:Palliative Care; D014057:Tomography, X-Ray Computed; D014132:Trachea / Q000473:pathology; D014134:Tracheal Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy