title: Fat or fiction: origins matter.
abstract: Cell-lineage tracing has revealed a complex heterogeneity present in postnatal tissue and adult progenitors. Chau et al. (2014) and Long et al. (2014) provide further evidence for this among adipocytes, and their findings underscore the importance of cellular ontogeny not just for development but also for potential treatment of disease.
authors.affiliation: Hagey Laboratory for Pediatric Regenerative Medicine, Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University Medical Center, Stanford, CA 94305, USA.
authors.forename: Derrick C
authors.initials: DC
authors.lastname: Wan
authors.affiliation: Hagey Laboratory for Pediatric Regenerative Medicine, Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University Medical Center, Stanford, CA 94305, USA; Institue for Stem Cell Biology and Regenerative Medicine, Stanford University Medical Center, Stanford, CA 94305, USA. Electronic address: longaker@stanford.edu.
authors.forename: Michael T
authors.initials: MT
authors.lastname: Longaker
mesh_terms: D017667:Adipocytes / Q000378:metabolism*; D002001:Adipose Tissue, Brown / Q000378:metabolism*; D052436:Adipose Tissue, White / Q000378:metabolism*; D000818:Animals; D005260:Female; D009130:Muscle, Smooth / Q000378:metabolism*; D025721:WT1 Proteins / Q000378:metabolism*
chemical_list: D025721:WT1 Proteins