title: Red emissive two-photon probe for real-time imaging of mitochondria trafficking.
abstract: Mitochondria trafficking plays an essential role for supplying energy in the neuronal system. We report here a red emissive two-photon probe for mitochondria (CMT-red) that showed high selectivity and robust staining ability for mitochondria, high photostability under a two-photon microscopy imaging condition, and low cytotoxicity. This probe can be easily loaded into live cells and tissue and used for real-time, high resolution imaging of the mitochondria trafficking in primary cortical neurons as well as in rat hippocampal tissue.
authors.affiliation: Department of Energy Systems Research, Ajou University , Suwon, Gyeonggi-do 443-749, Korea.
authors.forename: Avik R
authors.initials: AR
authors.lastname: Sarkar
authors.forename: Cheol Ho
authors.initials: CH
authors.lastname: Heo
authors.forename: Hyo Won
authors.initials: HW
authors.lastname: Lee
authors.forename: Kyung Hee
authors.initials: KH
authors.lastname: Park
authors.forename: Young Ho
authors.initials: YH
authors.lastname: Suh
authors.forename: Hwan Myung
authors.initials: HM
authors.lastname: Kim
mesh_terms: D000818:Animals; D001692:Biological Transport; D006624:Hippocampus / Q000378:metabolism; D008928:Mitochondria / Q000378:metabolism*; D015335:Molecular Probes; D017785:Photons; D051381:Rats
chemical_list: D015335:Molecular Probes