title: Chemical constituents from the fungus Chaetomium cupreum RY202.
abstract: Two new angular types of azaphilones, isochromophilonol (1) and ochrephilonol (2), together with ten known compounds (3-12), were isolated from Chaetomium cupreum RY202. Their structures were established on the basis of spectroscopic data and the absolute configurations of 1 and 3 were determined by the modified Mosher's method. Compounds 1, 2 and 4 showed moderated cytotoxicity against KB and NCI-H187 cell lines (IC50 9.63-32.42 µg/mL).
authors.affiliation: Department of Applied Chemistry, Faculty of Sciences and Liberal Arts, Rajamangala University of Technology Isan, Nakhon Ratchasima, 3000, Thailand.
authors.forename: Natcha
authors.initials: N
authors.lastname: Panthama
authors.forename: Somdej
authors.initials: S
authors.lastname: Kanokmedhakul
authors.forename: Kwanjai
authors.initials: K
authors.lastname: Kanokmedhakul
authors.forename: Kasem
authors.initials: K
authors.lastname: Soytong
mesh_terms: D045744:Cell Line, Tumor; D002597:Chaetomium / Q000737:chemistry* / Q000302:isolation & purification*; D006801:Humans; D061986:MCF-7 Cells