title: Advances in research on cis-9, trans-11 conjugated linoleic acid: a major functional conjugated linoleic acid isomer.
abstract: Conjugated linoleic acid (CLA) consists of a group of positional and geometric conjugated isomers of linoleic acid. Since the identification of CLA as a factor that can inhibit mutagenesis and carcinogenesis, thousands of studies have been conducted in the last several decades. Among the many isomers discovered, cis-9, trans-11 CLA is the most intensively studied because of its multiple, isomer-specific effects in humans and animals. This paper provides an overview of the available data on cis-9, trans-11 CLA, including its isomer-specific effects, biosynthesis, in vivo/in vitro research models, quantification, and the factors influencing its content in ruminant products.
authors.affiliation: a Department of Animal Science, and Technology, College of Animal Bioscience & Technology , Konkuk University , 120 Neungdong-ro, Gwangjin-gu , Seoul 143-701 , Republic of Korea.
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.forename: Hong Gu
authors.initials: HG
authors.lastname: Lee
mesh_terms: D000818:Animals; D005527:Food, Fortified; D006801:Humans; D007536:Isomerism; D044243:Linoleic Acids, Conjugated / Q000096:biosynthesis* / Q000737:chemistry*; D012106:Research / Q000639:trends
chemical_list: D044243:Linoleic Acids, Conjugated; C503589:cis-9, trans-11-conjugated linoleic acid
keywords: Conjugated linoleic acid; biosynthesis; cis-9; in vivo/in vitro research models; isomer-specific effects; quantification; trans-11 CLA