title: Hyperreactive Malarious Splenomegaly and AIDS: a case report.
abstract: Malaria is endemic in the North of Brazil. However, Hyperreactive Malarious Splenomegaly (HMS) has been rarely described. Splenomegaly in HIV/Aids infection has a large differential diagnosis, but malaria is a cause of gross splenomegaly, regardless of the HIV status. In this paper, we report the case of a 50-year-old man, HIV positive, with massive splenomegaly and multiple malaria infections in the past. He fulfilled the criteria for HMS, received a short course of anti-malarial treatment and weekly quimioprofilatic Chloroquine. In 9 months, he had great clinical and laboratorial improvement confirming the HMS, a rare diagnosis in Brazil.
authors.affiliation: Departamento de Clínica Médica, Universidade Estadual de Londrina, Londrina, PR, Brazil. Electronic address: zntanno@terra.com.br.
authors.forename: Zuleica Naomi
authors.initials: ZN
authors.lastname: Tano
authors.affiliation: Universidade Estadual de Londrina, Londrina, PR, Brazil.
authors.forename: Chafic Esper Kallas
authors.initials: CE
authors.lastname: Filho
authors.affiliation: Departamento de Ciências Patologicas, Universidade Estadual de Londrina, Londrina, PR, Brazil.
authors.forename: Regina Mitsuka
authors.initials: RM
authors.lastname: Breganó
authors.affiliation: Departamento de Ciências Patologicas, Universidade Estadual de Londrina, Londrina, PR, Brazil.
authors.forename: Wander Rogério
authors.initials: WR
authors.lastname: Pavanelli
authors.affiliation: Universidade Estadual de Londrina, Londrina, PR, Brazil.
authors.forename: Uheyna Gancedo
authors.initials: UG
authors.lastname: Ruzon
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D006801:Humans; D008288:Malaria / Q000150:complications*; D008297:Male; D008875:Middle Aged; D013163:Splenomegaly / Q000209:etiology*
keywords: Aids; Hyperreactivemalarious splenomegaly