title: [Pathological assessment of bone sarcomas].
abstract: Bone tumors are very rare. Diagnosis and treatment is an interdisciplinary task for experienced radiologists, pathologist, and surgeons that is ideally performed in specialized centers. For optimal processing of bone specimens, basic laboratory equipment and special techniques are required. The cornerstone of the histological diagnosis remains H&E staining, supplemented by special stains, immunohistochemistry, and molecular techniques. For an appropriate diagnosis, data on clinical history, age, location, topography within bone, and imaging are required. Major differences between histological and radiological diagnosis have to be clarified before starting treatment (e.g., by involving a reference registry).
authors.affiliation: Knochentumor-Referenzzentrum am Institut für Pathologie, Universitätsspital Basel, Schoenbeinstraße 40, CH-4031, Basel, Schweiz, gernot.jundt@unibas.ch.
authors.forename: G
authors.initials: G
authors.lastname: Jundt
authors.forename: D
authors.initials: D
authors.lastname: Baumhoer
mesh_terms: D062005:Biopsy, Large-Core Needle / Q000379:methods*; D001859:Bone Neoplasms / Q000737:chemistry* / Q000473:pathology*; D004396:Coloring Agents / Q000737:chemistry; D004801:Eosine Yellowish-(YS) / Q000737:chemistry*; D006416:Hematoxylin / Q000737:chemistry*; D006801:Humans; D008853:Microscopy / Q000379:methods; D012516:Osteosarcoma / Q000737:chemistry* / Q000473:pathology*; D013194:Staining and Labeling / Q000379:methods
chemical_list: D004396:Coloring Agents; D004801:Eosine Yellowish-(YS); D006416:Hematoxylin