title: Bowenoid papulosis successfully treated with imiquimod 5% cream.
abstract: A 24-year-old healthy Japanese female was diagnosed as having bowenoid papulosis in the genital area. The histopathological findings revealed acanthosis, papillomatosis, dyskeratotic cells and clumping cells with mild atypical nuclei. Human papillomavirus type 16 was detected in the lesion. The lesion was successfully treated with topical imiquimod 5% cream after 2 months. Imiquimod 5% cream is a potentially effective treatment modality for lesions that are difficult to treat with surgical excision.
authors.affiliation: Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Shimizu
authors.forename: Madoka
authors.initials: M
authors.lastname: Kato
authors.forename: Osamu
authors.initials: O
authors.lastname: Ishikawa
mesh_terms: D000279:Administration, Cutaneous; D000634:Aminoquinolines / Q000008:administration & dosage*; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D005260:Female; D052162:Human papillomavirus 16 / Q000302:isolation & purification; D006801:Humans; D000077271:Imiquimod; D030361:Papillomavirus Infections / Q000188:drug therapy*; D017193:Skin Diseases, Viral / Q000188:drug therapy*; D014845:Vulvar Diseases / Q000188:drug therapy*; D055815:Young Adult
chemical_list: D000634:Aminoquinolines; D000970:Antineoplastic Agents; D000077271:Imiquimod
keywords: HPV typing; bowenoid papulosis; human papillomavirus; imiquimod