title: Clinical outcomes of colonic mucosal cancers with histologically positive or uncertain resection margin after endoscopic resection.
abstract: OBJECTIVE
  Although incomplete endoscopic resection of colonic neoplasms can lead to the development of interval invasive cancer, few studies have assessed clinical outcomes after histologically incomplete resection of colonic mucosal cancer. We aimed to evaluate the clinical outcomes of patients with histologically positive or uncertain resection margins after endoscopically complete resection of colonic mucosal cancer.
  
  
  METHODS
  We analyzed the clinical course of 38 patients (median 62 years, male:female = 27:11) who underwent endoscopically complete resection of colonic mucosal cancer, but who showed histologically positive or uncertain resection margins.
  
  
  RESULTS
  The median size of the 38 colonic mucosal cancers was 14 mm (range, 5-50 mm). Of these, 20 were resected by a piecemeal resection, and had uncertain histological resection margins. The remaining 18 patients underwent en-bloc resection; of these, 16 had uncertain resection margins and 2 had positive margins. Patients underwent a median of 2.3 follow-up endoscopies (range, 1-7) during a median follow-up time of 18.3 months (range, 3-75 months). No local or distant recurrence was detected.
  
  
  CONCLUSIONS
  Cautious followup without immediate additional treatment can be considered for patients who undergo endoscopically complete resection of colonic mucosal cancers, even when histological examination shows uncertain or positive resection margins.
authors.forename: Ock Bae
authors.initials: OB
authors.lastname: Ko
authors.forename: Jeong-Sik
authors.initials: JS
authors.lastname: Byeon
authors.forename: Mi Jung
authors.initials: MJ
authors.lastname: Kim
authors.forename: Hyun
authors.initials: H
authors.lastname: Lim
authors.forename: Min Jung
authors.initials: MJ
authors.lastname: Kim
authors.forename: Dong-Hoon
authors.initials: DH
authors.lastname: Yang
authors.forename: Soon Man
authors.initials: SM
authors.lastname: Yoon
authors.forename: Kyung-Jo
authors.initials: KJ
authors.lastname: Kim
authors.forename: Byong Duk
authors.initials: BD
authors.lastname: Ye
authors.forename: Seung-Jae
authors.initials: SJ
authors.lastname: Myung
authors.forename: Suk-Kyun
authors.initials: SK
authors.lastname: Yang
authors.forename: Jin-Ho
authors.initials: JH
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003110:Colonic Neoplasms / Q000473:pathology* / Q000601:surgery*; D003113:Colonoscopy; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012189:Retrospective Studies; D016896:Treatment Outcome