title: Liver parenchymal sparing surgery for locally advanced gallbladder cancer with extracapsular lymph node invasion.
abstract: A complete R0 resection is the standard treatment in patients with gallbladder cancer and the only potentially definitive curative therapy. Major hepatectomy, including right or extended right hepatectomy with extrahepatic bile duct resection, would be an option in patients with locally advanced gallbladder cancer, while morbidity and mortality rate are still high. Herein, we report a case of a locally advanced gallbladder cancer invading the right hepatic artery (RHA), common hepatic duct, and transverse colon. This patient was successfully treated with parenchymal sparing surgery without major hepatectomy and achieved R0 resection by means of extended cholecystectomy combined with resection of the transverse colon, extrahepatic bile duct, and RHA. Intrahepatic arterial flow was preserved without reconstruction of the RHA, and the postoperative course was favorable. Liver parenchymal sparing surgery might be an alternative procedure in patients with gallbladder cancer, to minimize the risk of severe morbidity, if R0 resection is possible.
authors.affiliation: Department of Surgery, National Hospital Organization, Kyoto Medical Center, 1-1 Mukaihata-cho, Fukakusa, Fushimi-ku, Kyoto 612-8555, Japan. narinari@kuhp.kyoto-u.ac.jp.
authors.forename: Masato
authors.initials: M
authors.lastname: Narita
authors.forename: Ryo
authors.initials: R
authors.lastname: Matsusue
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Hata
authors.forename: Takashi
authors.initials: T
authors.lastname: Yamaguchi
authors.forename: Tetsushi
authors.initials: T
authors.lastname: Otani
authors.forename: Iwao
authors.initials: I
authors.lastname: Ikai
mesh_terms: D017734:Bile Ducts, Extrahepatic / Q000473:pathology / Q000601:surgery*; D002763:Cholecystectomy; D005260:Female; D005706:Gallbladder Neoplasms / Q000473:pathology / Q000601:surgery*; D006499:Hepatic Artery / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000601:surgery*; D008198:Lymph Nodes / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D059351:Organ Sparing Treatments; D011379:Prognosis