title: Evaluation of sentinel node biopsy for cutaneous squamous cell carcinoma.
abstract: Sentinel lymph node biopsy (SLNB) is a standard care for cutaneous melanoma but its role in cutaneous squamous cell carcinoma (SCC) has not been established. Clinical data was obtained from 54 patients with SCC who received SLNB with the usage of blue dye and radioisotope colloid methods. The positive rate of SLNB in SCC was 7.4%. If the cases were limited to more than T2, the positive rate was 12.9%. Three of 41 patients who was estimated negative LN metastasis by the preoperative tests had micrometastasis (7.3%). Among 13 patients who were suggested to have metastasis in the preoperative tests, only one patient had histological metastasis. One patient with SCC located in the lower lip showed negative SLNB and subsequently developed node recurrence. In conclusion, the efficacy of SLNB in SCC is comparable to that of melanoma in the positive rate. There are two kinds of benefit, avoidance of unnecessary complete lymph node dissection and early detection of metastasis.
authors.affiliation: Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Fukushima
authors.forename: Shinichi
authors.initials: S
authors.lastname: Masuguchi
authors.forename: Toshikatsu
authors.initials: T
authors.lastname: Igata
authors.forename: Miho
authors.initials: M
authors.lastname: Harada
authors.forename: Jun
authors.initials: J
authors.lastname: Aoi
authors.forename: Azusa
authors.initials: A
authors.lastname: Miyashita
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nakahara
authors.forename: Yuji
authors.initials: Y
authors.lastname: Inoue
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Jinnin
authors.forename: Shinya
authors.initials: S
authors.lastname: Shiraishi
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Yamashita
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Ishihara
authors.forename: Hironobu
authors.initials: H
authors.lastname: Ihn
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D021701:Sentinel Lymph Node Biopsy / Q000706:statistics & numerical data*; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*; D055815:Young Adult
keywords: false-negative; false-positive; lymph node metastasis; non-melanoma skin cancer; skin surgery