title: Effects of general and spinal anesthetic techniques on endothelial adhesion molecules in cesarean section.
abstract: BACKGROUND
  The aim of this study was to investigate the effects of anesthetic techniques used during general anesthesia (GA) and spinal anesthesia (SA) on endothelial adhesion molecules in the fetal circulation of healthy parturients undergoing elective cesarean section.
  
  
  METHODS
  Patients were randomly assigned to either the general anesthesia (n = 20) or spinal anesthesia (n = 20) group. Maternal and cord blood neopterin, sE-selectin, and sL-selectin levels were measured in both groups.
  
  
  RESULTS
  Cord blood neopterin concentrations in the SA group were not different from those in the GA group, but maternal neopterin levels in the SA group were different from those in the GA group. Maternal blood levels of sE-selectin and sL-selectin were not different between the two groups. Similarly, the cord blood levels of sE-selectin and sL-selectin were not different between the two groups. We found an increased inflammatory process in the fetal circulation depending on the anesthetic method used.
  
  
  CONCLUSIONS
  These results indicate the effects of general and spinal anesthetic techniques on serum sL-selectin, sE-selectin, and neopterin levels in neonates and parturients undergoing elective cesarean section. sE-selectin and neopterin concentrations and leukocyte counts were higher in the fetal circulation than in the maternal circulation during both GA and SA.
authors.affiliation: Department of Anesthesiology and Reanimation, Kecioren Training and Research Hospital, Ankara, Turkey.
authors.forename: Mehtap
authors.initials: M
authors.lastname: Honca
authors.affiliation: Department of Anesthesiology and Reanimation, Gulhane Military Medical Academy, Ankara, Turkey.
authors.forename: Tarık
authors.initials: T
authors.lastname: Purtuloglu
authors.affiliation: Department of Medical Biochemistry, Gulhane Military Medical Academy, Ankara, Turkey.
authors.forename: Emin Ozgur
authors.initials: EO
authors.lastname: Akgul
authors.affiliation: Department of Biochemistry, Turkish Armed Forces, Health Services Command, Etimesgut, Ankara, Turkey.
authors.forename: Muzaffer
authors.initials: M
authors.lastname: Oztosun
authors.affiliation: Department of Medical Biochemistry, Gulhane Military Medical Academy, Ankara, Turkey.
authors.forename: Tevfik
authors.initials: T
authors.lastname: Honca
authors.affiliation: Department of Anesthesiology and Reanimation, Gulhane Military Medical Academy, Ankara, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Sizlan
authors.affiliation: Department of Medical Biochemistry, Gulhane Military Medical Academy, Ankara, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Agilli
authors.affiliation: Department of Medical Biochemistry, Gulhane Military Medical Academy, Ankara, Turkey.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Aydin
authors.affiliation: Department of Anesthesiology and Reanimation, Gulhane Military Medical Academy, Ankara, Turkey.
authors.forename: Memduh
authors.initials: M
authors.lastname: Yetim
authors.affiliation: Department of Medical Biochemistry, Gulhane Military Medical Academy, Ankara, Turkey.
authors.forename: Fevzi Nuri
authors.initials: FN
authors.lastname: Aydin
authors.affiliation: Department of Medical Biochemistry, Gulhane Military Medical Academy, Ankara, Turkey.
authors.forename: Halil
authors.initials: H
authors.lastname: Yaman
keywords: Cesarean section; Endothelial adhesion molecules; General anesthesia; Spinal anesthesia