title: Persistent posttreatment fatigue in thyroid cancer survivors: a scoping review.
abstract: The relevance of persistent posttreatment fatigue (PPF) to thyroid cancer (TC) survivor populations is not known. This article presents a scoping review, which is an overview of published research activity. Uncontrolled data suggest that PPF is one of the most common complaints in TC survivors. Furthermore, statistically significantly worse levels of fatigue were reported in TC survivors, compared with the general population or healthy controls. There was some inconsistency among PPF risk factors. More research is needed on PPF in TC survivors, including long-term prospective cohort studies, research on fatigue severity prevalence, and randomized controlled trials of treatment strategies.
authors.affiliation: Division of Endocrinology, Department of Medicine, University Health Network, 200 Elizabeth Street, 12th Floor, Toronto, Ontario M5G 2C4, Canada; Division of Endocrinology, Department of Medicine, University of Toronto, 200 Elizabeth Street, 12 EN-243, Toronto, Ontario M5G 2C4, Canada. Electronic address: Annie.Sawka@uhn.ca.
authors.forename: Anna M
authors.initials: AM
authors.lastname: Sawka
authors.affiliation: Division of Endocrinology, Department of Medicine, University Health Network, 200 Elizabeth Street, 12th Floor, Toronto, Ontario M5G 2C4, Canada.
authors.forename: Asima
authors.initials: A
authors.lastname: Naeem
authors.affiliation: Department of Psychiatry, University of Toronto, 250 College Street, 8th Floor, Toronto, Ontario M5T 1R8, Canada; Cancer Survivorship Program, Princess Margaret Hospital, University Health Network, 200 Elizabeth Street, Bcs-045, Toronto, Ontario M5G 2C4, Canada.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Jones
authors.affiliation: Division of Endocrinology, Department of Medicine, University of Toronto, 200 Elizabeth Street, 12 EN-243, Toronto, Ontario M5G 2C4, Canada; Division of Endocrinology, Department of Medicine, Sunnybrook Health Sciences Center, 2075 Bayview Avenue, H Wing, Toronto, Ontario M4N 3M5, Canada.
authors.forename: Julia
authors.initials: J
authors.lastname: Lowe
authors.affiliation: Division of Endocrinology, Department of Medicine, University Health Network, 200 Elizabeth Street, 12th Floor, Toronto, Ontario M5G 2C4, Canada; Division of Endocrinology, Department of Medicine, University of Toronto, 200 Elizabeth Street, 12 EN-243, Toronto, Ontario M5G 2C4, Canada; Division of Endocrinology, Department of Medicine, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada.
authors.forename: Philip
authors.initials: P
authors.lastname: Segal
authors.affiliation: Division of Endocrinology, Department of Medicine, University of Toronto, 200 Elizabeth Street, 12 EN-243, Toronto, Ontario M5G 2C4, Canada; Division of Endocrinology, Department of Medicine, St. Michael's Hospital, 61 Queen Street East, 6th Floor, Toronto, Ontario M5C 2T2, Canada.
authors.forename: Jeannette
authors.initials: J
authors.lastname: Goguen
authors.affiliation: Division of Endocrinology, Department of Medicine, University of Toronto, 200 Elizabeth Street, 12 EN-243, Toronto, Ontario M5G 2C4, Canada; Division of Endocrinology, Department of Medicine, Sunnybrook Health Sciences Center, 2075 Bayview Avenue, H Wing, Toronto, Ontario M4N 3M5, Canada.
authors.forename: Jeremy
authors.initials: J
authors.lastname: Gilbert
authors.affiliation: Division of Endocrinology, Department of Medicine, University of Toronto, 200 Elizabeth Street, 12 EN-243, Toronto, Ontario M5G 2C4, Canada; Division of Endocrinology, Department of Medicine, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada; Division of Endocrinology, Department of Medicine, Women's College Hospital, 76 Grenville Street, Toronto, Ontario M5S 1B2, Canada.
authors.forename: Afshan
authors.initials: A
authors.lastname: Zahedi
authors.affiliation: Division of Endocrinology, Department of Medicine, University of Toronto, 200 Elizabeth Street, 12 EN-243, Toronto, Ontario M5G 2C4, Canada; Division of Endocrinology, Department of Medicine, Women's College Hospital, 76 Grenville Street, Toronto, Ontario M5S 1B2, Canada.
authors.forename: Catherine
authors.initials: C
authors.lastname: Kelly
authors.affiliation: Endocrine Oncology Site Group, Princess Margaret Hospital, University Health Network, 200 Elizabeth Street, 12NU-1200, Toronto, Ontario M5G 2C4, Canada.
authors.forename: Shereen
authors.initials: S
authors.lastname: Ezzat
mesh_terms: D005221:Fatigue / Q000209:etiology*; D006801:Humans; D011788:Quality of Life; D017741:Survivors; D013964:Thyroid Neoplasms / Q000150:complications* / Q000628:therapy*
keywords: Fatigue; Quality of life; Survivorship; Thyroid cancer; Vitality