title: Clozapine and cancer treatment: Adding to the experience and evidence.
abstract: The judiciousness of the use of clozapine in patients with schizophrenia in clinical practice is brought to an even sharper focus when it has to be used in combination with other agents that cause myelosuppression, for example, chemotherapy and radiation treatment. There are a few references till date illustrating the combination of clozapine and chemotherapy and/or radiation therapy. To the best of our knowledge, such a case has not been reported from India. We report the case of a 39-year-old gentleman with a diagnosis of schizophrenia, remaining psychiatrically stable on clozapine, who underwent combination treatment of chemotherapy and radiotherapy for the treatment of cancer of the tongue in a tertiary care oncology centre in India.
authors.affiliation: Psychiatric Unit and Department of Palliative Care, Tata Memorial Hospital, Dr. E Borges Road, Parel, Mumbai, Maharashtra, India.
authors.forename: Jayita K
authors.initials: JK
authors.lastname: Deodhar
authors.affiliation: Department of Medical Oncology, Tata Memorial Hospital, Dr. E Borges Road, Parel, Mumbai, Maharashtra, India.
authors.forename: Kumar
authors.initials: K
authors.lastname: Prabhash
authors.affiliation: Department of Radiation Oncology, Tata Memorial Hospital, Dr. E Borges Road, Parel, Mumbai, Maharashtra, India.
authors.forename: Jai P
authors.initials: JP
authors.lastname: Agarwal
authors.affiliation: Department of Head and Neck Surgical Oncology, Tata Memorial Hospital, Dr. E Borges Road, Parel, Mumbai, Maharashtra, India.
authors.forename: Pankaj
authors.initials: P
authors.lastname: Chaturvedi
keywords: Cancer; chemotherapy; clozapine; radiation therapy