title: Composition of a neuromere and its segmental diversification under the control of Hox genes in the embryonic CNS of Drosophila.
abstract: Studies performed at the level of single, identified cells in the fruitfly Drosophila have decisively contributed to our understanding of the mechanisms underlying the development and function of the nervous system. This review highlights some of the work based on single-cell analyses in the embryonic/larval CNS that sheds light on the principles underlying formation and organization of an entire segmental unit and its divergence along the anterior/posterior body axis.
authors.affiliation: Institute of Genetics, University of Mainz , Mainz , Germany.
authors.forename: Gerhard M
authors.initials: GM
authors.lastname: Technau
authors.forename: Ana
authors.initials: A
authors.lastname: Rogulja-Ortmann
authors.forename: Christian
authors.initials: C
authors.lastname: Berger
authors.forename: Oliver
authors.initials: O
authors.lastname: Birkholz
authors.forename: Christof
authors.initials: C
authors.lastname: Rickert
mesh_terms: D000818:Animals; D019521:Body Patterning / Q000235:genetics*; D002490:Central Nervous System / Q000196:embryology*; D004330:Drosophila / Q000196:embryology / Q000235:genetics*; D029721:Drosophila Proteins / Q000235:genetics*; D005801:Genes, Homeobox
chemical_list: D029721:Drosophila Proteins
keywords: CNS; Drosophila; Hox genes; cell lineage; segmental patterning; single-cell tracing