title: Radiation-induced morphoea treated with UVA-1 phototherapy.
abstract: Morphoea is a localized inflammatory disorder of the dermis and subcutaneous fat and radiotherapy is a rarely reported cause (estimated incidence of 2 per 1000). Morphoea is commonly mistaken for an inflammatory recurrence of breast cancer, resulting in unnecessary investigations and treatment. We report the case of a 40-year-old woman who developed radiation-induced morphoea of the breast 7 months following adjuvant radiotherapy. She was treated with topical and systemic steroids as well as psoralen plus ultraviolet (UV)A before proceeding to UVA1 phototherapy. We also review the literature and discuss other management options.
authors.affiliation: Department of Dermatology, Chelsea and Westminster Hospital, London, UK.
authors.forename: D
authors.initials: D
authors.lastname: Lim
authors.forename: S
authors.initials: S
authors.lastname: Johnston
authors.forename: L
authors.initials: L
authors.lastname: Novakovic
authors.forename: L
authors.initials: L
authors.lastname: Fearfield
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000532:radiotherapy; D005260:Female; D006801:Humans; D011832:Radiation Injuries / Q000532:radiotherapy*; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects*; D012594:Scleroderma, Localized / Q000209:etiology / Q000532:radiotherapy*; D016896:Treatment Outcome; D014467:Ultraviolet Therapy / Q000379:methods*