title: Reliability and validity of Leicester Cough Questionnaire Korean version.
abstract: The Leicester Cough Questionnaire (LCQ) is a self-administered questionnaire developed in England and validated for reliability. We developed a Korean translation of this questionnaire by applying a sequential forward and backward translation approach. The purpose of this study is to validate the Korean version of the LCQ (LCQ-K) in Korean patients with chronic cough. A multicenter prospective study was undertaken with 100 chronic cough patients who consented to participate in the study. The LCQ-K includes eight physical items, seven psychological items, and four social items. Visual analog scale (VAS) of cough, Borg Cough Scale (BCS), and Short Form-36 (SF-36) were used as external comparators. Participants included 52 women and 48 men with ages ranging from 18 years to 69 years. The concurrent validity comparing LCQ-K to VAS, BCS, and SF-36 yielded statistically significant Pearson correlation coefficients. The LCQ-K showed good reliability in three domains, with Cronbach's α coefficients ranging from 0.84 to 0.87 (total: 0.91). Test-retest reliability was investigated with single measure intraclass correlation coefficients, which were found to be practically and statistically significant (p = 0.005). Responsiveness was validated by effective size ranging from 1.16 to 1.40 in each domain. LCQ-K is a reliable, valid, and responsive disease-specific questionnaire for assessing symptoms and quality of life of Korean patients with chronic cough.
authors.affiliation: College of Korean Medicine, Daejeon University, Daejeon, South Korea.
authors.forename: Jong-Min
authors.initials: JM
authors.lastname: Han
authors.affiliation: College of Korean Medicine, Daejeon University, Daejeon, South Korea.
authors.forename: In-Chul
authors.initials: IC
authors.lastname: Jung
authors.affiliation: College of Business Administration, Daejeon University, Daejeon, South Korea.
authors.forename: Weechang
authors.initials: W
authors.lastname: Kang
authors.affiliation: Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Daejeon, South Korea.
authors.forename: Seung-Su
authors.initials: SS
authors.lastname: Kim
authors.affiliation: College of Pharmacy, Purdue University, West Lafayette, IN, USA Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
authors.forename: Yoon
authors.initials: Y
authors.lastname: Yeo
authors.affiliation: College of Korean Medicine, Daejeon University, Daejeon, South Korea omdpyc@dju.kr.
authors.forename: Yang-Chun
authors.initials: YC
authors.lastname: Park
keywords: Chronic cough; Leicester Cough Questionnaire; quality of life; reliability; validity