title: [The MitraClip procedure].
abstract: Mitral insufficiency is a frequently occurring valvular disease for which surgery is the reference treatment. A large number of patients are at high risk or even contraindicated for surgery due to comorbidities. The MitraClip procedure reproduces a surgical technique for mitral valve repair. Global experience includes over 12,000 patients and has been mainly reported in registries with limited follow-up. The degree of reduction of mitral insufficiency is less with the MitraClip than with surgery. Safety of the procedure is good in experienced centres. Most patients have functional improvement in the mid-term. The procedure may be considered in patients who are at high risk for surgery and remain symptomatic despite optimal medical treatment. In the future, more data are needed from longer follow-up and randomised trials. Both the technique and the equipment used in the procedure need to improve. In addition, it is hoped that combined percutaneous procedures will be available in the near future.
authors.affiliation: Hôpital Bichat, université Paris VII, département de cardiologie, service de chirurgie cardiaque, 75018 Paris, France. Electronic address: alec.vahanian@bch.aphp.fr.
authors.forename: Alec
authors.initials: A
authors.lastname: Vahanian
authors.affiliation: Hôpital Bichat, université Paris VII, département de cardiologie, service de chirurgie cardiaque, 75018 Paris, France.
authors.forename: Dominique
authors.initials: D
authors.lastname: Himbert
authors.affiliation: Hôpital Bichat, université Paris VII, département de cardiologie, service de chirurgie cardiaque, 75018 Paris, France.
authors.forename: Eric
authors.initials: E
authors.lastname: Brochet
authors.affiliation: Hôpital Bichat, université Paris VII, département de cardiologie, service de chirurgie cardiaque, 75018 Paris, France.
authors.forename: Bernard
authors.initials: B
authors.lastname: Iung
authors.affiliation: Hôpital Bichat, université Paris VII, département de cardiologie, service de chirurgie cardiaque, 75018 Paris, France.
authors.forename: David
authors.initials: D
authors.lastname: Messika-Zeitoun
authors.affiliation: Hôpital Bichat, université Paris VII, département de cardiologie, service de chirurgie cardiaque, 75018 Paris, France.
authors.forename: Patrick
authors.initials: P
authors.lastname: Nataf
mesh_terms: D006348:Cardiac Surgical Procedures / Q000295:instrumentation* / Q000379:methods*; D004867:Equipment Design; D006801:Humans; D008944:Mitral Valve Insufficiency / Q000601:surgery*