title: Colonic metastasis after resection of primary squamous cell carcinoma of the lung: a case report and literature review.
abstract: Lung cancer is a common malignancy in the world; however symptomatic colonic metastasis from primary lung cancer is rare. A 64-year-old man was originally found poorly differentiated squamous cell carcinoma of right lung and received right lower lobectomy and lymph node dissection. Three years later, the patient presented to our emergency room with the symptom of upper abdominal pain and weight loss. Abdominal palpation and computed tomography scan of the abdomen revealed a large mass measuring 7.6 cm × 8.5 cm in the ascending colon. Colonoscopy and biopsy revealed poorly differentiated squamous cell carcinoma with similar morphological pattern to that of the previous lung cancer. Chemotherapy was given and the patient died 5 mo later. Lung cancer metastatic to the colon confers a poor prognosis: overall survival ranged from 5 wk to 1 year, with a median survival of 3 mo after the diagnosis of the colonic metastasis.
authors.affiliation: Hai-Zhou Lou, Hong-Ming Pan, Qin Pan, Department of Medical Oncology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310000, Zhejiang Province, China.
authors.forename: Hai-Zhou
authors.initials: HZ
authors.lastname: Lou
authors.affiliation: Hai-Zhou Lou, Hong-Ming Pan, Qin Pan, Department of Medical Oncology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310000, Zhejiang Province, China.
authors.forename: Chun-Hua
authors.initials: CH
authors.lastname: Wang
authors.affiliation: Hai-Zhou Lou, Hong-Ming Pan, Qin Pan, Department of Medical Oncology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310000, Zhejiang Province, China.
authors.forename: Hong-Ming
authors.initials: HM
authors.lastname: Pan
authors.affiliation: Hai-Zhou Lou, Hong-Ming Pan, Qin Pan, Department of Medical Oncology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310000, Zhejiang Province, China.
authors.forename: Qin
authors.initials: Q
authors.lastname: Pan
authors.affiliation: Hai-Zhou Lou, Hong-Ming Pan, Qin Pan, Department of Medical Oncology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310000, Zhejiang Province, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Wang
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery*; D002454:Cell Differentiation; D003110:Colonic Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000556:secondary*; D003113:Colonoscopy; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents
keywords: Chemotherapy; Colonic metastasis; Lung neoplasm; Squamous cell carcinoma