title: Chronic Conjunctivitis due to Nocardia nova Complex Formation on a Silicone Stent: A Case Report and Review of the Literature.
abstract: Nocardial conjunctivitis associated with silicone tubing is an extremely rare finding. The authors present a case of a 52-year-old woman with previous dacryocystorhinostomy and silicone tube placement 3 years prior who presented with OD redness and discharge for 1 week. On examination, the patient was noted to have mucoid discharge and crusting surrounding the silicone tube. The tube debris was sampled, and the culture was positive for Nocardia nova complex sensitive to trimethoprim/sulfamethoxazole and amikacin. Silicone tube colonization and N. nova complex conjunctivitis are both rare but should be considered in the differential diagnosis of patients with indwelling silicone tubes presenting with chronic conjunctivitis resistant to fluoroquinolones and tobramycin.
authors.affiliation: Department of Ophthalmology, Baylor College of Medicine, Houston, Texas, U.S.A.
authors.forename: John M
authors.initials: JM
authors.lastname: Micheletti
authors.forename: Megha
authors.initials: M
authors.lastname: Agrawal
authors.forename: Alice Y
authors.initials: AY
authors.lastname: Matoba
authors.forename: Douglas P
authors.initials: DP
authors.lastname: Marx
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002908:Chronic Disease; D003234:Conjunctivitis, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D003608:Dacryocystorhinostomy / Q000295:instrumentation; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D007440:Intubation / Q000295:instrumentation; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009615:Nocardia / Q000302:isolation & purification*; D009617:Nocardia Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D016459:Prosthesis-Related Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D012826:Silicone Elastomers; D015607:Stents / Q000382:microbiology*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D012826:Silicone Elastomers; D015662:Trimethoprim, Sulfamethoxazole Drug Combination