title: [Ultrastructural changes in endothelial cells of blood capillaries of the Walker 256 carcinosarcoma while treated with melatonin].
abstract: In Wistar rats with transplanted Walker 256 carcinosarcoma a use of melatonin as monoagent causes changes in intracellular organization of endothelial cells: reduced volume density of mitochondria, granular cytoplasmic network, micropinocytic vesicles, reduced the number density of free and attached ribosomes, which leads to increased apoptosis of tumor cells of Walker 256 carcinosarcoma.
authors.forename: E V
authors.initials: EV
authors.lastname: Ovsianko
authors.forename: M G
authors.initials: MG
authors.lastname: Pustovetova
authors.forename: E N
authors.initials: EN
authors.lastname: Samsonova
authors.forename: Ia U
authors.initials: IaU
authors.lastname: Ovsianko
authors.forename: R G
authors.initials: RG
authors.lastname: Fedina
authors.forename: A O
authors.initials: AO
authors.lastname: Kulishenko
authors.forename: A S
authors.initials: AS
authors.lastname: Vinogradov
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D002196:Capillaries / Q000473:pathology*; D002279:Carcinoma 256, Walker / Q000473:pathology* / Q000648:ultrastructure; D003593:Cytoplasm / Q000187:drug effects; D042783:Endothelial Cells / Q000648:ultrastructure*; D008297:Male; D008550:Melatonin / Q000008:administration & dosage / Q000494:pharmacology*; D008928:Mitochondria / Q000187:drug effects; D010873:Pinocytosis / Q000187:drug effects; D051381:Rats; D012270:Ribosomes / Q000187:drug effects
chemical_list: D000970:Antineoplastic Agents; D008550:Melatonin