title: Oxygen saturation profile in late-preterm and term infants: a prospective cohort study.
abstract: OBJECTIVE
  To determine oxygen saturation profile over 6 h monitoring period in healthy late-preterm and term neonates during the first 48 h of age, and to assess the impact of gestational age, birth weight and method of delivery on this profile.
  
  
  METHODS
  Prospective cohort study of measurement of SpO2 over 6 h in 20 late-preterm (35 to 36 weeks gestation) and 40 term infants within 12 to 48 h of birth was conducted. Infants with cardiorespiratory symptoms or need for cardiorespiratory support at birth were excluded. Percentage time spent at SpO2 >90% and ⩽90% was calculated by gestational age and birth weight.
  
  
  RESULTS
  Late-preterm infants and infants born weighing <2.5 kg spent approximately 7% of the time at SpO2 ⩽90%; this time decreased as gestational age and birth weight increased. Time at SpO2 >90% was significantly different between late-preterm and term infants (93% (5%) vs 96% (3%); P =0.002). Time at SpO2 >90% was not significantly different between males and females (95% (5%) vs 95% (4%), both n=30; P =0.72) or between vaginal births and cesarean births (95% (4%), n=32, vs 95% (4%), n=28; P =0.39). Cumulative time with SpO2 <90 was mean (s.d.) of 25 (18) in preterm vs 13 (10) min in term infants.
  
  
  CONCLUSIONS
  Over a 6-h period healthy late-preterm and term infants spent significant time at SpO2 ⩽90%. Lower gestation and lower birth weight were associated with higher time at SpO2 ⩽90%.
authors.affiliation: Department of Paediatrics, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.
authors.forename: P S
authors.initials: PS
authors.lastname: Shah
authors.affiliation: Department of Paediatrics, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.
authors.forename: H
authors.initials: H
authors.lastname: Hakak
authors.affiliation: Department of Paediatrics, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.
authors.forename: A
authors.initials: A
authors.lastname: Mohamed
authors.affiliation: Department of Paediatrics, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.
authors.forename: J
authors.initials: J
authors.lastname: Shah
authors.affiliation: Department of Paediatrics, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.
authors.forename: J
authors.initials: J
authors.lastname: Young
authors.affiliation: Department of Paediatrics, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.
authors.forename: E
authors.initials: E
authors.lastname: Kelly
mesh_terms: D001724:Birth Weight / Q000502:physiology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn / Q000502:physiology*; D007234:Infant, Premature / Q000502:physiology*; D008297:Male; D010100:Oxygen / Q000097:blood*; D011446:Prospective Studies
chemical_list: D010100:Oxygen