title: A case suspected for yellow fever vaccine-associated viscerotropic disease in the Netherlands.
abstract: Yellow fever (YF) 17D vaccine is one of the most successful vaccines ever developed. Since 2001, 56 cases of yellow fever vaccine-associated viscerotropic disease (YEL-AVD) have been published in the peer-reviewed literature. Here, we report a new case suspected for YEL-AVD in the Netherlands. Further research is needed to determine the true incidence of YEL-AVD and to clarify host and vaccine-associated factors in the pathogenesis of YEL-AVD. Because of the potential adverse events, healthcare providers should carefully consider vaccination only in people who are truly at risk for YF infection, especially in primary vaccine recipients.
authors.affiliation: Department of Internal and Infectious Diseases, Rijnstate Hospital, Arnhem, the Netherlands.
authors.forename: Eva M
authors.initials: EM
authors.lastname: van de Pol
authors.forename: Elizabeth H
authors.initials: EH
authors.lastname: Gisolf
authors.forename: Clemens
authors.initials: C
authors.lastname: Richter
mesh_terms: D015746:Abdominal Pain / Q000821:virology; D000328:Adult; D006261:Headache / Q000821:virology; D006801:Humans; D008297:Male; D009102:Multiple Organ Failure / Q000821:virology*; D009325:Nausea / Q000821:virology; D009426:Netherlands; D012075:Remission, Spontaneous; D014195:Travel; D014613:Vaccines, Attenuated / Q000009:adverse effects; D015004:Yellow Fever / Q000276:immunology / Q000517:prevention & control*; D022341:Yellow Fever Vaccine / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D014613:Vaccines, Attenuated; D022341:Yellow Fever Vaccine