title: Left atrial appendage wall-motion velocity associates with recurrence of nonparoxysmal atrial fibrillation after catheter ablation.
abstract: Catheter ablation (CA) for nonparoxysmal atrial fibrillation (AF) is controversial due to its high recurrence rate. The aim of this study was to assess retrospectively the diagnostic value of preprocedural left atrial appendage (LAA) wall-motion velocity in predicting recurrence of AF within 1 year after CA. We hypothesized that tissue Doppler-derived measurement of LAA wall-motion velocity associate with recurrence of AF within 1 year after CA. We retrospectively reviewed 47 consecutive patients with nonparoxysmal AF (defined as AF lasting for 1 week or longer) who underwent both transthoracic and transesophageal echocardiography before their first treatment by CA in a single center. Forty-one patients aged 58 ± 10 years were included, and variables predicting the recurrence of AF within 1 year after CA were evaluated. Seventeen patients (41%) developed recurrence of AF within 1 year after CA. Univariate analyses showed that preprocedural LAA upward wall-motion velocity at the apex assessed by transesophageal echocardiography was significantly lower in patients with recurrence of AF than those without recurrence (OR = 1.45, 95% CI: 1.13-2.01, P = 0.009). Multivariate logistic analyses including other potential predictors (duration of AF, left ventricular ejection fraction, E-wave deceleration time, and left atrial wall-motion velocity) identified LAA upward wall-motion velocity at the apex as an independent predictor of outcome. These data suggest in patients with nonparoxysmal AF, preprocedural LAA upward wall-motion velocity at the apex, as determined by tissue Doppler imaging during transesophageal echocardiography, may be a useful indicator for predicting recurrence of AF within 1 year after CA.
authors.affiliation: Department of Cardiology, International Medical Center, Saitama Medical University, Saitama, Japan.
authors.forename: Miyuki
authors.initials: M
authors.lastname: Ariyama
authors.forename: Ritsushi
authors.initials: R
authors.lastname: Kato
authors.forename: Makoto
authors.initials: M
authors.lastname: Matsumura
authors.forename: Harumi
authors.initials: H
authors.lastname: Yoshimoto
authors.forename: Yoshie
authors.initials: Y
authors.lastname: Nakajima
authors.forename: Shintaro
authors.initials: S
authors.lastname: Nakano
authors.forename: Takatoshi
authors.initials: T
authors.lastname: Kasai
authors.forename: Jun
authors.initials: J
authors.lastname: Tanno
authors.forename: Takaaki
authors.initials: T
authors.lastname: Senbonmatsu
authors.forename: Kazuo
authors.initials: K
authors.lastname: Matsumoto
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Nishimura
mesh_terms: D020517:Atrial Appendage / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D001281:Atrial Fibrillation / Q000175:diagnosis*; D017115:Catheter Ablation; D015150:Echocardiography, Doppler; D017548:Echocardiography, Transesophageal; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012008:Recurrence; D012189:Retrospective Studies
keywords: atrial fibrillation; left atrial appendage function; tissue Doppler imaging