title: Datura stramonium intoxication in two children.
abstract: Datura stramonium is a toxic plant member of the Solanaceae family. Its consumption may result in severe anticholinergic toxicity. We report the intoxication of 5- and 4-year-old brothers with Datura stramonium, which presented in two different manners. The first child presented agitation, hallucination and mydriasis that improved rapidly with benzodiazepine medication. The second presented comatose, mydriasis and Babinski signs. Gastric lavage and activated charcoal administration were performed. The child was intubated and mechanically ventilated until consciousness improvement. Datura stramonium poisoning may be considered by physicians in case of acute onset of decreased consciousness or behaviour trouble associated with anticholinergic signs and symptoms.
authors.affiliation: Department of Anesthesia and Intensive Care, Fianarantsoa Teaching Hospital, Fianarantsoa, Madagascar.
authors.forename: Falihery
authors.initials: F
authors.lastname: Rakotomavo
authors.forename: Caroline
authors.initials: C
authors.lastname: Andriamasy
authors.forename: Ndrantoniaina
authors.initials: N
authors.lastname: Rasamoelina
authors.forename: Nasolotsiry
authors.initials: N
authors.lastname: Raveloson
mesh_terms: D001569:Benzodiazepines / Q000627:therapeutic use; D002606:Charcoal / Q000627:therapeutic use; D002675:Child, Preschool; D013286:Datura stramonium / Q000506:poisoning*; D005751:Gastric Lavage; D006801:Humans; D008297:Male; D010939:Plant Poisoning / Q000628:therapy
chemical_list: D001569:Benzodiazepines; D002606:Charcoal
keywords: Datura stramonium; agitation; anticholinergic toxicity; comatose; intoxication