title: Impact of Nonosseous Findings on (18)F-NaF PET/CT in a Patient with Ductal Breast Carcinoma.
abstract: (18)F-NaF was used as a bone-seeking PET tracer for skeletal imaging until the introduction of the widely available (99m)Tc-labeled bone agents. However, there is renewed clinical interest in (18)F-NaF since prior technical and logistic limitations to its routine use are no longer present, and, as a consequence, it is likely that uptake unrelated to bone and non-osseous findings will be encountered more frequently. As a result of tumoral necrosis, soft tissue metastases may demonstrate (18)F-NaF avidity due to dystrophic calcification. On the other hand, all non-osseous findings, whether (18)F-NaF avid or not, may provide important diagnostic information that may alter the course of the disease, including treatment options. Herein we present a patient with ductal carcinoma of the breast in whom findings unrelated to the skeletal system in (18)F-NaF PET/CT altered the treatment strategy.
authors.affiliation: Istanbul Medical Faculty, Department of Nuclear Medicine, Istanbul University, 34093 Fatih, Istanbul Turkey.
authors.forename: Serkan
authors.initials: S
authors.lastname: Kuyumcu
authors.affiliation: Istanbul Medical Faculty, Department of Nuclear Medicine, Istanbul University, 34093 Fatih, Istanbul Turkey.
authors.forename: Isik
authors.initials: I
authors.lastname: Adalet
authors.affiliation: Istanbul Medical Faculty, Department of Nuclear Medicine, Istanbul University, 34093 Fatih, Istanbul Turkey.
authors.forename: Emine Goknur
authors.initials: EG
authors.lastname: Isik
authors.affiliation: Istanbul Medical Faculty, Department of Nuclear Medicine, Istanbul University, 34093 Fatih, Istanbul Turkey.
authors.forename: Seher Nilgun
authors.initials: SN
authors.lastname: Unal
keywords: 18F-FDG PET/CT; 18F-NaF PET/CT; Bone metastasis; Breast carcinoma