title: [Health-related quality of life among patients with advanced cancer: an integrative review].
abstract: This integrative literature review aimed to characterize scientific articles on health-related quality of life - HRQoL - among patients with advanced cancer from national and international literature, and summarize those factors evidenced in the literature that contributed to the improvement or worsening of HRQoL among patients with advanced cancer. The search for materials was conducted in the following databases: CINAHL, EMBASE, PubMed, SciELO and LILACS. Among the 21 articles in the sample, 13 showed an improvement of HRQoL among patients with advanced cancer related to the development of physical, emotional and spiritual interventions. In eight studies, we identified predictive symptoms of low HRQoL, such as pain, fatigue, sleep disorders, depression, nutritional changes, and others. The results showed that clinical manifestations, which many times were inherent in cancer, such as factors that can lower patients' HRQoL, while physical, psychological and spiritual benefits resulting from therapeutic interventions may promote its improvement.
authors.affiliation: Department of Clinic Nursing, Federal University of Paraíba, João Pessoa, PB, Brazil, enfelimoreirafreire@gmail.com.
authors.forename: Maria Eliane Moreira
authors.initials: ME
authors.lastname: Freire
authors.affiliation: Ribeirão Preto School of Nursing, University of Sao Paulo, Ribeirão Preto, SP, Brazil.
authors.forename: Namie Okino
authors.initials: NO
authors.lastname: Sawada
authors.affiliation: State University of Paraíba, Joao Pessoa, PB, Brazil.
authors.forename: Inácia Sátiro Xavier
authors.initials: IS
authors.lastname: de França
authors.affiliation: Santa Emília Rodat University, Joao Pessoa, PB, Brazil.
authors.forename: Solange Fátima Geraldo
authors.initials: SF
authors.lastname: da Costa
authors.affiliation: Santa Emília Rodat University, Joao Pessoa, PB, Brazil.
authors.forename: Cecília Danielle Bezerra
authors.initials: CD
authors.lastname: Oliveira
mesh_terms: D006801:Humans; D009369:Neoplasms; D011788:Quality of Life