title: Systematic examination of the fetal abdominal precordial veins: a cohort study.
abstract: OBJECTIVE
  Examination of the fetal venous system is a necessary part of complete fetal organ scanning to confirm landmark anatomy, such as the ductus venosus and course of the umbilical veins, and, whenever cardiovascular anomalies are identified, to exclude associated anomalous development of the fetal veins. We aimed to develop a protocol for systematic examination of the fetal venous system during midtrimester targeted organ scanning.
  
  
  METHODS
  We included low-risk women with a singleton fetus presenting between January 2011 and June 2013 to our center for routine midtrimester (20-24 weeks) targeted organ scanning. Imaging of the venous system was added to the booked scan and comprised two-dimensional color Doppler scanning of the fetal abdomen in three discrete planes, two transverse and one longitudinal. The more caudal plane was obtained in a ventral or lateral transverse abdominal plane to image the umbilical vein, left portal vein, portal sinus, anterior right portal vein, posterior right portal vein, main portal vein and splenic vein and artery. Moving cephalad, a ventral or lateral transverse plane was obtained to image the right, middle and left hepatic veins and inferior vena cava (IVC). Finally, a longitudinal anteroposterior plane showed the umbilical vein, ductus venosus, IVC and left hepatic vein. In some cases the pulsed Doppler waveform of a given target vessel was also examined. Three-dimensional/4D ultrasound was applied as necessary, when anomalous cases were encountered.
  
  
  RESULTS
  We examined 1810 women. Their body mass index ranged from 19 to 40 (mean, 24.7). In 38 (2.1%) women, the target anatomy was not visualized satisfactorily owing to maternal body habitus. A T-shaped configuration of the portal system vessels was observed in 63% of cases, an X-shaped configuration in 25% and an H-shaped configuration in 12%. During the study period, 24 congenital anomalies of the precordial venous system were diagnosed: nine cases of persistent right umbilical vein, seven of agenesis of the ductus venosus, five of anomalous portal venous drainage and three of interrupted IVC with azygos continuation.
  
  
  CONCLUSIONS
  Examination of the fetal venous system is feasible with the application of three abdominal planes. While a venous system scan is not practicable as part of a screening-level examination, mastery of the normal anatomy is an essential part of the professional knowledge base, in order to provide ready and complete scanning of the system in cases of suspected anomalies or disordered cardiac function.
authors.affiliation: Division of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Centers, Jerusalem, Israel.
authors.forename: S
authors.initials: S
authors.lastname: Yagel
authors.forename: S M
authors.initials: SM
authors.lastname: Cohen
authors.forename: D V
authors.initials: DV
authors.lastname: Valsky
authors.forename: O
authors.initials: O
authors.lastname: Shen
authors.forename: M
authors.initials: M
authors.lastname: Lipschuetz
authors.forename: B
authors.initials: B
authors.lastname: Messing
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging* / Q000196:embryology; D000328:Adult; D002318:Cardiovascular Diseases / Q000000981:diagnostic imaging* / Q000196:embryology / Q000473:pathology; D005260:Female; D047109:Fetal Development; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging* / Q000196:embryology; D011169:Portal Vein / Q000196:embryology / Q000473:pathology*; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011446:Prospective Studies; D016216:Ultrasonography, Prenatal; D014471:Umbilical Veins / Q000000981:diagnostic imaging* / Q000196:embryology
keywords: IVC; ductus venosus; hepatic veins; portal system; splenic vein; umbilical vein; venous system