title: A close correlation between plasma and serum levels of brain-derived neurotrophic factor (BDNF) in healthy volunteers.
abstract: Abstract Objective. Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophic family found in both the central and the peripheral nervous system. Blood BDNF levels are considered as a state marker for depression. Methods. We investigated serum and plasma levels of BDNF levels in 103 healthy volunteers (M/F: 39/64, age: 37±12 years) using ELISA methods. Results and Conclusions. Serum BDNF levels were 14-fold higher than plasma BDNF levels, and a close relationship was found between serum and plasma BDNF levels.
authors.affiliation: Department of Psychiatry, University of Occupational and Environmental Health, Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, Japan.
authors.forename: Reiji
authors.initials: R
authors.lastname: Yoshimura
authors.forename: Atsuko
authors.initials: A
authors.lastname: Sugita-Ikenouchi
authors.forename: Hikaru
authors.initials: H
authors.lastname: Hori
authors.forename: Wakako
authors.initials: W
authors.lastname: Umene-Nakano
authors.forename: Kenji
authors.initials: K
authors.lastname: Hayashi
authors.forename: Asuka
authors.initials: A
authors.lastname: Katsuki
authors.forename: Nobuhisa
authors.initials: N
authors.lastname: Ueda
authors.forename: Jun
authors.initials: J
authors.lastname: Nakamura
keywords: Brain-derived neurotrophic factor; plasma; serum