title: Murine Typhus: Clinical and epidemiological aspects.
abstract: is an intracellular bacteria who causes murine typhus. His importance is reflected in the high frequency founding specific antibodies against Rickettsia typhi in several worldwide seroepidemiological studies, the seroprevalence ranging between 3-36%. Natural reservoirs of R. typhi are rats (some species belonging the Rattus Genus) and fleas (Xenopsylla cheopis) are his vector. This infection is associated with overcrowding, pollution and poor hygiene. Typically presents fever, headache, rash on trunk and extremities, in some cases may occur organ-specific complications, affecting liver, kidney, lung or brain. Initially the disease is very similar to other diseases, is very common to confuse the murine typhus with Dengue fever, therefore, ignorance of the disease is a factor related to complications or non-specific treatments for the resolution of this infection. This paper presents the most relevant information to consider about the rickettsiosis caused by Rickettsia typhi.
authors.affiliation: Universidad Autónoma de Yucatán, México gaspar.peniche@uady.mx ; Unidad Interinstitucional de Investigaciónclínica y Epidemiológica, Facultad de Medicina, zavala@uady.mx.
authors.forename: Gaspar
authors.initials: G
authors.lastname: Peniche Lara
authors.affiliation: Universidad Autónoma de Yucatán, México gaspar.peniche@uady.mx ; Centro de Investigaciónes Regionales Dr Hideyo Noguchi, Facultad de Medicina. zcastro@uady.mx.
authors.forename: Karla R
authors.initials: KR
authors.lastname: Dzul-Rosado
authors.affiliation: Universidad Autónoma de Yucatán, México gaspar.peniche@uady.mx ; Unidad Interinstitucional de Investigaciónclínica y Epidemiológica, Facultad de Medicina, zavala@uady.mx.
authors.forename: Jorge Ernesto
authors.initials: JE
authors.lastname: Zavala Velázquez
authors.affiliation: Universidad Autónoma de Yucatán, México gaspar.peniche@uady.mx ; Centro de Investigaciónes Regionales Dr Hideyo Noguchi, Facultad de Medicina. zcastro@uady.mx.
authors.forename: Jorge
authors.initials: J
authors.lastname: Zavala-Castro
keywords: Rickettsia; Rickettsia typhi; fleas; infection; rats; rickettsioses