title: Change in hippocampal theta activity with transfer from simple discrimination tasks to a simultaneous feature-negative task.
abstract: It was showed that solving a simple discrimination task (A+, B-) and a simultaneous feature-negative (FN) task (A+, AB-) used the hippocampal-independent strategy. Recently, we showed that the number of sessions required for a rat to completely learn a task differed between the FN and simple discrimination tasks, and there was a difference in hippocampal theta activity between these tasks. These results suggested that solving the FN task relied on a different strategy than the simple discrimination task. In this study, we provided supportive evidence that solving the FN and simple discrimination tasks involved different strategies by examining changes in performance and hippocampal theta activity in the FN task after transfer from the simple discrimination task (A+, B- → A+, AB-). The results of this study showed that performance on the FN task was impaired and there was a difference in hippocampal theta activity between the simple discrimination task and FN task. Thus, we concluded that solving the FN task uses a different strategy than the simple discrimination task.
authors.affiliation: Department of Systems Neuroscience, Graduate School of Medicine, Yamaguchi University Yamaguchi, Japan.
authors.forename: Yuya
authors.initials: Y
authors.lastname: Sakimoto
authors.affiliation: Department of Behavioral Sciences, Graduate School of Integrated Arts and Sciences, Hiroshima University Hiroshima, Japan.
authors.forename: Shogo
authors.initials: S
authors.lastname: Sakata
keywords: hippocampal theta activity; hippocampal-independent strategy; rat; simple discrimination task; simultaneous feature-negative task