title: Endometrial cancer: a review and current management strategies: part I.
abstract: Endometrial carcinoma is the most common gynecologic malignancy. A thorough understanding of the epidemiology, pathophysiology, and management strategies for this cancer allows the obstetrician-gynecologist to identify women at increased risk, contribute toward risk reduction, and facilitate early diagnosis. The Society of Gynecologic Oncology's Clinical Practice Committee has reviewed the literature and created evidence-based practice recommendations for diagnosis and treatment. This article examines: • Risk factors, including genetic predisposition • Diagnostic and metastatic evaluation • Surgical management of early and advanced cancer, including lymphadenectomy in early cancer.
authors.affiliation: Division of Gynecologic Oncology Valley Hospital, Paramus, NJ, USA; Columbia University Medical Center, New York, NY, USA. Electronic address: wmb7@columbia.edu.
authors.forename: William M
authors.initials: WM
authors.lastname: Burke
authors.affiliation: Medical Director, Florida Gynecologic Oncology, Fort Meyers, FL, USA.
authors.forename: James
authors.initials: J
authors.lastname: Orr
authors.affiliation: Gynecology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
authors.forename: Mario
authors.initials: M
authors.lastname: Leitao
authors.affiliation: Division of Gynecologic Oncology, Florida International University, Miami, FL, USA.
authors.forename: Emery
authors.initials: E
authors.lastname: Salom
authors.affiliation: Division of Gynecologic Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
authors.forename: Paola
authors.initials: P
authors.lastname: Gehrig
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
authors.forename: Alexander B
authors.initials: AB
authors.lastname: Olawaiye
authors.affiliation: Division of Gynecologic Oncology, Carole and Ray Neag Comprehensive Cancer Center, University of Connecticut Health Center, Farmington, CT, USA.
authors.forename: Molly
authors.initials: M
authors.lastname: Brewer
authors.affiliation: Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA, USA.
authors.forename: Dave
authors.initials: D
authors.lastname: Boruta
authors.forename: Jeannine
authors.initials: J
authors.lastname: Villella
authors.affiliation: Division of Gynecologic Oncology, Winthrop University Hospital, Long Island, NY, USA; Division of Gynecologic Oncology, SUNY Stony Brook School of Medicine, Long Island, NY, USA.
authors.forename: Jeanine
authors.initials: J
authors.lastname: Villella
authors.affiliation: Division of Gynecologic Oncology, Columbia University Medical Center, New York, NY, USA.
authors.forename: Tom
authors.initials: T
authors.lastname: Herzog
authors.affiliation: Florida Gynecologic Oncology, Fort Meyers, FL, USA.
authors.forename: Fadi
authors.initials: F
authors.lastname: Abu Shahin
mesh_terms: D016889:Endometrial Neoplasms / Q000175:diagnosis* / Q000601:surgery*; D005260:Female; D006801:Humans
keywords: Diagnosis; Endometrial cancer; Evaluation; Review; Risk factors; Surgery