title: Peptide-catalyzed kinetic resolution of planar-chiral metallocenes.
abstract: Kinetic resolution of racemic planar-chiral metallocenes was performed through the conjugate addition of a nucleophile to the enal part of substrates. While no enantiomeric discrimination was found with low-molecular-weight organocatalysts, a properly designed resin-supported peptide catalyzed the reaction in a highly selective manner.
authors.affiliation: Institute of Industrial Science, University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan. kkudo@iis.u-tokyo.ac.jp.
authors.forename: Midori
authors.initials: M
authors.lastname: Akiyama
authors.forename: Kengo
authors.initials: K
authors.lastname: Akagawa
authors.forename: Hidetake
authors.initials: H
authors.lastname: Seino
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Kudo
mesh_terms: D002384:Catalysis; D007700:Kinetics; D009942:Organometallic Compounds / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D009942:Organometallic Compounds; D010455:Peptides; C013108:metallocene