title: Is ultrasound screening reliable for adverse local tissue reaction after hip arthroplasty?
abstract: There is increasing awareness of prevalence of adverse local tissue reaction (ALTR) surrounding metal-on-metal (MoM) and highly cross-linked polyethylene (HXLPE) bearings, and sensitive and simple screening modalities for ALTR are required. We examined reliability of ultrasound screening for ALTR in 131 hips of 105 patients who received both ultrasound and MRI examinations after hip arthroplasty with MoM or HXLPE bearings. Using the MRI results as reference, sensitivity, specificity and accuracy of ultrasound were 74%, 92% and 84% around MoM bearings, and 90%, 83%, and 85% around HXLPE bearings. Ultrasound detected ALTR in 11 hips that were not shown with MRI. Ultrasound examination is assumed to be a reliable screening tool for detecting clinically important ALTR lesions developing in the anterior region around MoM or HXLPE bearings.
authors.affiliation: Department of Orthopaedic Medical Engineering, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Nishii
authors.affiliation: Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Sakai
authors.affiliation: Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Masaki
authors.initials: M
authors.lastname: Takao
authors.affiliation: Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Hideki
authors.initials: H
authors.lastname: Yoshikawa
authors.affiliation: Department of Orthopaedic Medical Engineering, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Sugano
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D005260:Female; D005549:Foreign-Body Reaction / Q000000981:diagnostic imaging*; D006615:Hip / Q000000981:diagnostic imaging / Q000473:pathology*; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008403:Mass Screening; D061825:Metal-on-Metal Joint Prostheses / Q000009:adverse effects*; D008875:Middle Aged; D020959:Polyethylene / Q000009:adverse effects*; D011474:Prosthesis Design; D011475:Prosthesis Failure; D015203:Reproducibility of Results; D014463:Ultrasonography
chemical_list: D020959:Polyethylene
keywords: MRI; adverse local tissue reaction; reliability; total hip arthroplasty; ultrasound