title: Iron around the clock.
abstract: Carbon assimilation, a key determinant of plant biomass production, is under circadian regulation. Light and temperature are major inputs of the plant clock that control various daily rhythms. Such rhythms confer adaptive advantages to the organisms by adjusting their metabolism in anticipation of environmental fluctuations. The relationship between the circadian clock and nutrition extends far beyond the regulation of carbon assimilation as mineral nutrition, and specially iron homeostasis, is regulated through this mechanism. Conversely, iron status was identified as a new and important input regulating the central oscillator, raising the question of the nature of the Fe-dependent signal that modulates the period of the circadian clock. Several lines of evidence strongly suggest that fully developed and functional chloroplasts as well as early light signalling events, involving phytochromes, are essential to couple the clock to Fe responses. Nevertheless, the exact nature of the signal, which most probably involves unknown or not yet fully characterized elements of the chloroplast-to-nucleus retrograde signalling pathway, remains to be identified. Finally, this regulation may also involves epigenetic components.
authors.affiliation: Laboratoire de Biochimie et Physiologie Moléculaire des Plantes (INRA, CNRS, Montpellier SupAgro, Université Montpellier 2), 34060 Montpellier Cedex 2, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Tissot
authors.affiliation: Laboratoire de Biochimie et Physiologie Moléculaire des Plantes (INRA, CNRS, Montpellier SupAgro, Université Montpellier 2), 34060 Montpellier Cedex 2, France.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Przybyla-Toscano
authors.affiliation: Laboratoire de Biochimie et Physiologie Moléculaire des Plantes (INRA, CNRS, Montpellier SupAgro, Université Montpellier 2), 34060 Montpellier Cedex 2, France.
authors.forename: Guilhem
authors.initials: G
authors.lastname: Reyt
authors.affiliation: Laboratoire de Biochimie et Physiologie Moléculaire des Plantes (INRA, CNRS, Montpellier SupAgro, Université Montpellier 2), 34060 Montpellier Cedex 2, France.
authors.forename: Baptiste
authors.initials: B
authors.lastname: Castel
authors.affiliation: Laboratoire de Biochimie et Physiologie Moléculaire des Plantes (INRA, CNRS, Montpellier SupAgro, Université Montpellier 2), 34060 Montpellier Cedex 2, France.
authors.forename: Céline
authors.initials: C
authors.lastname: Duc
authors.affiliation: Laboratoire de Biochimie et Physiologie Moléculaire des Plantes (INRA, CNRS, Montpellier SupAgro, Université Montpellier 2), 34060 Montpellier Cedex 2, France.
authors.forename: Jossia
authors.initials: J
authors.lastname: Boucherez
authors.affiliation: Laboratoire de Biochimie et Physiologie Moléculaire des Plantes (INRA, CNRS, Montpellier SupAgro, Université Montpellier 2), 34060 Montpellier Cedex 2, France.
authors.forename: Frédéric
authors.initials: F
authors.lastname: Gaymard
authors.affiliation: Laboratoire de Biochimie et Physiologie Moléculaire des Plantes (INRA, CNRS, Montpellier SupAgro, Université Montpellier 2), 34060 Montpellier Cedex 2, France. Electronic address: briat@supagro.inra.fr.
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Briat
authors.affiliation: Laboratoire de Biochimie et Physiologie Moléculaire des Plantes (INRA, CNRS, Montpellier SupAgro, Université Montpellier 2), 34060 Montpellier Cedex 2, France. Electronic address: christian.dubos@supagro.inra.fr.
authors.forename: Christian
authors.initials: C
authors.lastname: Dubos
mesh_terms: D017360:Arabidopsis / Q000378:metabolism*; D002736:Chloroplasts / Q000378:metabolism*; D057906:Circadian Clocks; D002940:Circadian Rhythm; D007501:Iron / Q000378:metabolism*; D008027:Light; D017440:Photoperiod; D010834:Phytochrome / Q000378:metabolism
chemical_list: D010834:Phytochrome; D007501:Iron
keywords: Arabidopsis thaliana; Chloroplast; Circadian clock; Iron homeostasis; Retrograde signalling