title: Ring expansion of cyclic 1,2-diols to form medium sized rings via ruthenium catalyzed transfer hydrogenative [4+2] cycloaddition.
abstract: A new method for the ring expansion of cyclic diols is described. Using improved conditions for the ruthenium(0) catalyzed cycloaddition of cyclic 1,2-diols with 1,3-dienes, fused [n.4.0] bicycles (n = 3-6) are formed, which upon exposure to iodosobenzene diacetate engage in oxidative cleavage to form the 9-12 membered rings .
authors.affiliation: Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, TX 78712, USA. mkrische@mail.utexas.edu.
authors.forename: Zachary A
authors.initials: ZA
authors.lastname: Kasun
authors.forename: Laina M
authors.initials: LM
authors.lastname: Geary
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Krische
mesh_terms: D002384:Catalysis; D003500:Cyclization; D061565:Cycloaddition Reaction / Q000379:methods*; D006865:Hydrogenation; D012428:Ruthenium / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D012428:Ruthenium