title: Tumor formation and antitumor immunity; the overlooked significance of histamine.
abstract: HA is a biogenic amine, widely distributed throughout the body. Given the observations that HA, the decarboxylated amino acid histidine, can be induced and made available in an unstored, diffusible form in tissues undergoing rapid growth (such as tumors and regenerating tissues), it could have a role in antitumor response beyond the well-studied inflammatory and allergic responses.
authors.affiliation: Department of Genetics, Cell and Immunobiology, Semmelweis University, Budapest, Hungary afalus@gmail.com.
authors.forename: Andras
authors.initials: A
authors.lastname: Falus
authors.affiliation: Department of Genetics, Cell and Immunobiology, Semmelweis University, Budapest, Hungary.
authors.forename: Anna
authors.initials: A
authors.lastname: Gilicze
mesh_terms: D000818:Animals; D006632:Histamine / Q000276:immunology*; D006801:Humans; D009369:Neoplasms / Q000276:immunology* / Q000473:pathology
chemical_list: D006632:Histamine
keywords: biogenic amine; cancer; immune response; regulation