title: Leuprolide acetate-induced generalized papular eruption.
abstract: Leuprolide acetate, a gonadotropin-releasing hormone agonist, is used in the treatment of prostate cancer. We report a unique case of a disseminated papular rash following leuprolide acetate injections in a 65-year-old man that shares clinical and histopathological features of papuloerythroderma of Ofuji. Leuprolide-induced papuloerythroderma, as well as a limited number of other disseminated cutaneous eruptions caused by this drug, is extremely rare, with only one case previously reported. Our case calls attention to this uncommon side effect in a commonly used hormonal therapy.
authors.forename: Katy
authors.initials: K
authors.lastname: Burris
authors.forename: Catherine Y
authors.initials: CY
authors.lastname: Ding
authors.forename: Geoffrey F S
authors.initials: GF
authors.lastname: Lim
mesh_terms: D000368:Aged; D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D006801:Humans; D016729:Leuprolide / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D011471:Prostatic Neoplasms / Q000188:drug therapy
chemical_list: D018931:Antineoplastic Agents, Hormonal; D016729:Leuprolide