title: A photothermal cell viability-reporting theranostic nanoprobe for intraoperative optical ablation and tracking of tumors.
abstract: A photothermal pH-reporting nanoprobe was developed for intraoperative tumor detection by "turn-on" fluorescence of the probe inside viable tumor cells, photothermal tumor therapy, and in situ monitoring of tumor killing by non-fluorescence of the probe in damaged cells.
authors.affiliation: Department of Chemical Biology, College of Chemistry and Chemical Engineering, Key Laboratory for Chemical Biology of Fujian Province, MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, Innovation Center for Cell Biology, Xiamen University, Xiamen 361005, China. shoufa@xmu.edu.cn.
authors.forename: Shuqi
authors.initials: S
authors.lastname: Wu
authors.forename: Shoufa
authors.initials: S
authors.lastname: Han
authors.forename: Jiahuai
authors.initials: J
authors.lastname: Han
authors.forename: Xinhui
authors.initials: X
authors.lastname: Su
mesh_terms: D000818:Animals; D016923:Cell Death / Q000187:drug effects; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival; D004195:Disease Models, Animal; D005260:Female; D005456:Fluorescent Dyes / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D006367:HeLa Cells; D056945:Hep G2 Cells; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008325:Mammary Neoplasms, Experimental / Q000188:drug therapy* / Q000473:pathology; D051379:Mice; D008807:Mice, Inbred BALB C; D015394:Molecular Structure; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D010778:Photochemotherapy; D013499:Surface Properties
chemical_list: D005456:Fluorescent Dyes