title: Cognitive enhancers (Nootropics). Part 1: drugs interacting with receptors. Update 2014.
abstract: Scientists working in the fields of Alzheimer's disease and, in particular, cognitive enhancers are very productive. The review "Cognitive enhancers (nootropics): drugs interacting with receptors" was accepted for publication in July 2012. Since then, new targets for the potential treatment of Alzheimer's disease were identified. This update describes drugs interacting with 42 receptors versus 32 receptors in the first paper. Some compounds progressed in their development, while many others were discontinued. The present review covers the evolution of research in this field through March 2014.
authors.affiliation: AC Immune SA, EPFL, Lausanne, Switzerland.
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Froestl
authors.affiliation: AC Immune SA, EPFL, Lausanne, Switzerland.
authors.forename: Andreas
authors.initials: A
authors.lastname: Muhs
authors.affiliation: AC Immune SA, EPFL, Lausanne, Switzerland.
authors.forename: Andrea
authors.initials: A
authors.lastname: Pfeifer
mesh_terms: D000544:Alzheimer Disease / Q000150:complications*; D003072:Cognition Disorders / Q000188:drug therapy* / Q000209:etiology*; D006801:Humans; D018697:Nootropic Agents / Q000627:therapeutic use*; D011956:Receptors, Cell Surface / Q000378:metabolism*
chemical_list: D018697:Nootropic Agents; D011956:Receptors, Cell Surface
keywords: Alzheimer's disease; cognitive enhancers; memantine; memory; nootropics; receptors