title: Hypereosinophilia in a boy with asthma and Varicella Zoster Virus infection.
abstract: Hypereosinophilia is a rare pediatric condition that could be secondary to infections, allergens, immunologic disorders or may be expression of a clonal proliferation. We report the case of an asthmatic boy aged 9 years who presented hypereosinophilia with spontaneous resolution. He had positive serum IgM antibodies to Varicella Zoster Virus while other tests, including genetic ones, gave negative results. Our findings suggest that in children with unexplained hypereosinophilia Varicella Zoster Virus infection should be investigated.
authors.affiliation: Department of Pediatrics, Department of Clinical and Experimental Medicine, Azienda Ospedaliera-Universitaria, University of Parma, Italy. margherita.varini@gmail.com.
authors.forename: Margherita
authors.initials: M
authors.lastname: Varini
authors.forename: Laura
authors.initials: L
authors.lastname: Rinaldi
authors.forename: Lorenza
authors.initials: L
authors.lastname: Bonetti
authors.forename: Fabiola
authors.initials: F
authors.lastname: Neri
authors.forename: Francesca
authors.initials: F
authors.lastname: Santamaria
authors.forename: Giovanna
authors.initials: G
authors.lastname: Stringari
authors.forename: Carlo
authors.initials: C
authors.lastname: Caffarelli
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis; D001249:Asthma / Q000097:blood / Q000150:complications*; D002648:Child; D003937:Diagnosis, Differential; D006562:Herpes Zoster / Q000097:blood / Q000150:complications*; D014645:Herpesvirus 3, Human / Q000276:immunology*; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D008297:Male
chemical_list: D000914:Antibodies, Viral