title: Hereditary spherocytosis diagnosed with the eosin-5'-maleimide binding test.
abstract: We describe three cases of hereditary spherocytosis (HS) diagnosed using the eosin-5'-maleimide (EMA) binding test and discuss the relevance of the EMA binding test. In Japan, this test is not widely used because the prevalence of HS is low. This test is a valuable screening test for the diagnosis of HS.
authors.affiliation: Department of Pediatrics, Iwata City Hospital, Iwata, Japan.
authors.forename: Toru
authors.initials: T
authors.lastname: Watanabe
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Ono
authors.forename: Iwao
authors.initials: I
authors.lastname: Tajima
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Ishigaki
authors.forename: Akio
authors.initials: A
authors.lastname: Hakamata
authors.forename: Masami
authors.initials: M
authors.lastname: Shirai
authors.forename: Akira
authors.initials: A
authors.lastname: Endoh
authors.forename: Teruaki
authors.initials: T
authors.lastname: Hongo
mesh_terms: D000328:Adult; D002648:Child; D004801:Eosine Yellowish-(YS) / Q000031:analogs & derivatives*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D013103:Spherocytosis, Hereditary / Q000175:diagnosis*
chemical_list: C033531:eosin maleimide; D004801:Eosine Yellowish-(YS)
keywords: congenital hemolytic anemia; eosin-5′-maleimide test; flow cytometry; hereditary spherocytosis