title: Cerebral astroblastoma: A radiopathological diagnosis.
abstract: Astroblastoma is a rare glial neoplasm whose histogenesis has been clarified recently. It primarily occurs in children and young adults. We are reporting a case of 12-year-old girl child who presented with features of raised intracranial tension and generalized tonic-clonic seizures. Brain magnetic resonance imaging revealed a large well-circumscribed, cystic lesion without perifocal edema, and enhancing mural nodule in right parietal region. A radiological differential diagnosis of pilocytic astrocytoma and cerebral astroblastoma was made. A complete excision was done and histologically the lesion turned out to be an astroblastoma. We review the histology, immunohistochemistry, and imaging features of astroblastoma and survey the current literature, treatment strategies, and prognostic aspects for the management of this rare neoplasm.
authors.affiliation: Department of Neurosurgery, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.
authors.forename: Deepak Kumar
authors.initials: DK
authors.lastname: Singh
authors.affiliation: Department of Radiodiagnosis, King George's Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Neha
authors.initials: N
authors.lastname: Singh
authors.affiliation: Department of Radiodiagnosis, King George's Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Ragini
authors.initials: R
authors.lastname: Singh
authors.affiliation: Department of Pathology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.
authors.forename: Nuzhat
authors.initials: N
authors.lastname: Husain
keywords: Astroblastoma; brain tumor; cystic tumor; glial tumor