title: Glacier moraine formation-mimicking colloidal particle assembly in microchanneled, bioactive hydrogel for guided vascular network construction.
abstract: This study demonstrates that a new method to align microparticles releasing bioactive molecules in microchannels of a hydrogel allows the guiding of growth direction and spacing of vascular networks.
authors.affiliation: Department of Chemical and Biomolecular Engineering, Institute of Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
authors.forename: Min Kyung
authors.initials: MK
authors.lastname: Lee
authors.forename: Max H
authors.initials: MH
authors.lastname: Rich
authors.forename: Artem
authors.initials: A
authors.lastname: Shkumatov
authors.forename: Jae Hyun
authors.initials: JH
authors.lastname: Jeong
authors.forename: Marni D
authors.initials: MD
authors.lastname: Boppart
authors.forename: Rashid
authors.initials: R
authors.lastname: Bashir
authors.forename: Martha U
authors.initials: MU
authors.lastname: Gillette
authors.forename: Jonghwi
authors.initials: J
authors.lastname: Lee
authors.forename: Hyunjoon
authors.initials: H
authors.lastname: Kong
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000494:pharmacology*; D001808:Blood Vessels / Q000187:drug effects / Q000502:physiology*; D002645:Chickens; D003102:Colloids / Q000737:chemistry*; D005612:Freeze Drying; D019015:Geologic Sediments / Q000737:chemistry*; D048091:Guided Tissue Regeneration / Q000379:methods*; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000494:pharmacology*; D046448:Ice Cover / Q000737:chemistry*; D019344:Lactic Acid / Q000737:chemistry; D008810:Mice, Inbred C57BL; D008863:Microspheres; D011100:Polyglycolic Acid / Q000737:chemistry; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D012038:Regeneration; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism
chemical_list: D001672:Biocompatible Materials; D003102:Colloids; D042461:Vascular Endothelial Growth Factor A; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D011100:Polyglycolic Acid; D019344:Lactic Acid
keywords: colloidal particle assembly; freezing-induced glacier moraine; guided vascular network; microchanneled hydrogel; shear stress