title: Antenatal Bartter syndrome.
abstract: Antenatal Bartter syndrome is characterized by severe polyhydramnios in mother leading to premature delivery. Antenatal treatment has proven effective to prevent these problems. Postnatally newborns suffer from recurrent episodes of severe dehydration and electrolyte imbalance which can lead to fatal outcome. These manifestations are likely to be overlooked and missed under the umbrella of diagnosis of prematurity. This premature newborn with antenatal polyhydramnios had severe manifestations of polyuria, recurrent dehydration, electrolyte derangements and metabolic alkalosis. She was managed accordingly but unfortunately could not survive beyond 4 weeks.
authors.affiliation: Department of Paediatrics, Quaid-e-Azam International Hospital, Islamabad.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Afzal
authors.affiliation: Department of Paediatrics, Quaid-e-Azam International Hospital, Islamabad.
authors.forename: Ejaz A
authors.initials: EA
authors.lastname: Khan
authors.affiliation: Department of Paediatrics, Quaid-e-Azam International Hospital, Islamabad.
authors.forename: Wisal A
authors.initials: WA
authors.lastname: Khan
authors.affiliation: Department of Paediatrics, Quaid-e-Azam International Hospital, Islamabad.
authors.forename: Viqas
authors.initials: V
authors.lastname: Anwar
authors.affiliation: Department of Paediatrics, Quaid-e-Azam International Hospital, Islamabad.
authors.forename: Asma
authors.initials: A
authors.lastname: Yaqoob
authors.affiliation: Department of Paediatrics, Quaid-e-Azam International Hospital, Islamabad.
authors.forename: Shahid
authors.initials: S
authors.lastname: Rafiq
authors.affiliation: Department of Obstetrician, Quaid-e-Azam International Hospital, Islamabad.
authors.forename: Shaheena
authors.initials: S
authors.lastname: Azam
mesh_terms: D001477:Bartter Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D002712:Chlorides / Q000378:metabolism; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007008:Hypokalemia / Q000097:blood / Q000209:etiology; D007010:Hyponatremia / Q000097:blood / Q000209:etiology; D007213:Indomethacin / Q000627:therapeutic use; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000097:blood / Q000175:diagnosis*; D007234:Infant, Premature; D011141:Polyuria / Q000097:blood / Q000209:etiology; D011247:Pregnancy; D014883:Water-Electrolyte Imbalance / Q000209:etiology* / Q000628:therapy
chemical_list: D002712:Chlorides; D007213:Indomethacin