title: Rothia aeria endocarditis in a patient with a bicuspid aortic valve: case report.
abstract: Rothia aeria is an uncommon pathogen mainly associated with endocarditis in case reports. In previous reports, endocarditis by R. aeria was complicated by central nervous system embolization. In the case we report herein, endocarditis by R. aeria was diagnosed after acute self-limited diarrhea. In addition to the common translocation of R. aeria from the oral cavity, we hypothesize the possibility of intestinal translocation. Matrix-assisted laser desorption ionization-time of flight mass spectrometry and genetic sequencing are important tools that can contribute to early and more accurate etiologic diagnosis of severe infections caused by Gram-positive rods.
authors.affiliation: Department of Infectious and Parasitic Diseases, Medical School, Universidade de São Paulo, São Paulo, SP, Brazil. Electronic address: ac_nicodemo@uol.com.br.
authors.forename: Antonio Carlos
authors.initials: AC
authors.lastname: Nicodemo
authors.affiliation: Department of Infectious and Parasitic Diseases, Medical School, Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Luiz Guilherme
authors.initials: LG
authors.lastname: Gonçalves
authors.affiliation: Department of Infectious and Parasitic Diseases, Medical School, Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Fatuma Catherine Atieno
authors.initials: FC
authors.lastname: Odongo
authors.affiliation: Microbiology Laboratory, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
authors.forename: Marines Dalla Valle
authors.initials: MD
authors.lastname: Martino
authors.affiliation: Department of Clinical Analysis, School of Pharmacy, Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Jorge Luiz Mello
authors.initials: JL
authors.lastname: Sampaio
mesh_terms: D000328:Adult; D001021:Aortic Valve / Q000002:abnormalities* / Q000382:microbiology; D018988:Bacterial Translocation; D000082882:Bicuspid Aortic Valve Disease; D004697:Endocarditis, Bacterial / Q000175:diagnosis / Q000382:microbiology*; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis* / Q000382:microbiology; D006349:Heart Valve Diseases / Q000175:diagnosis / Q000382:microbiology*; D006801:Humans; D008297:Male
keywords: Endocarditis; Intestinal translocation; Molecular diagnosis; Rothia aeria