title: On the distinct molecular architectures of dipping- and spray-LbL films containing lipid vesicles.
abstract: The introduction of spraying procedures to fabricate layer-by-layer (LbL) films has brought new possibilities for the control of molecular architectures and for making the LbL technique compliant with industrial processes. In this study we show that significantly distinct architectures are produced for dipping and spray-LbL films of the same components, which included DODAB/DPPG vesicles. The films differed notably in their thickness and stratified nature. The electrical response of the two types of films to aqueous solutions containing erythrosin was also different. With multidimensional projections we showed that the impedance for the DODAB/DPPG spray-LbL film is more sensitive to changes in concentration, being therefore more promising as sensing units. Furthermore, with surface-enhanced Raman scattering (SERS) we could ascribe the high sensitivity of the LbL films to adsorption of erythrosin.
authors.affiliation: DFQB, Faculdade de Ciências e Tecnologia, UNESP Univ Estadual Paulista, Presidente Prudente, SP 19060-900, Brazil. Electronic address: pedroaoki@gmail.com.
authors.forename: Pedro H B
authors.initials: PH
authors.lastname: Aoki
authors.affiliation: DFQB, Faculdade de Ciências e Tecnologia, UNESP Univ Estadual Paulista, Presidente Prudente, SP 19060-900, Brazil.
authors.forename: Priscila
authors.initials: P
authors.lastname: Alessio
authors.affiliation: São Carlos Institute of Physics, University of São Paulo, CP 369, São Carlos, SP 13560-970, Brazil.
authors.forename: Diogo
authors.initials: D
authors.lastname: Volpati
authors.affiliation: Institute of Mathematical and Computer Sciences, University of São Paulo, CP 668, São Carlos, SP 13560-970, Brazil.
authors.forename: Fernando V
authors.initials: FV
authors.lastname: Paulovich
authors.affiliation: Applied Physics Department, Gleb Wataghin Institute of Physics, State University of Campinas, UNICAMP, Campinas, SP 13083-859, Brazil.
authors.forename: Antonio
authors.initials: A
authors.lastname: Riul
authors.affiliation: São Carlos Institute of Physics, University of São Paulo, CP 369, São Carlos, SP 13560-970, Brazil.
authors.forename: Osvaldo N
authors.initials: ON
authors.lastname: Oliveira
authors.affiliation: DFQB, Faculdade de Ciências e Tecnologia, UNESP Univ Estadual Paulista, Presidente Prudente, SP 19060-900, Brazil.
authors.forename: Carlos J L
authors.initials: CJ
authors.lastname: Constantino
mesh_terms: D000327:Adsorption; D055664:Electrochemical Techniques; D004566:Electrodes; D004923:Erythrosine / Q000032:analysis / Q000737:chemistry; D008051:Lipid Bilayers / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D010715:Phosphatidylglycerols / Q000737:chemistry; D000644:Quaternary Ammonium Compounds / Q000737:chemistry; D013059:Spectrum Analysis, Raman; D014867:Water / Q000737:chemistry
chemical_list: D008051:Lipid Bilayers; D010715:Phosphatidylglycerols; D000644:Quaternary Ammonium Compounds; D014867:Water; C015831:dimethyldioctadecylammonium; D004923:Erythrosine; C030345:1,2-dipalmitoylphosphatidylglycerol
keywords: Erythrosin; Information visualization; Layer-by-layer films; Molecular architecture; Sensing