title: A self-assembled conformational switch: a host-guest stabilized triple stem molecular beacon via a photoactivated and thermal regeneration mode.
abstract: We present a novel strategy for construction of a conformational switch of a molecular beacon based on the combination of nucleic acid (DNA) self-assembly and reversible host-guest inclusion interaction. With the functionalized probe, the nucleic acid hybridization process can be easily controlled with a photoactivated and thermal regeneration mode.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, China. kmwang@hnu.edu.cn.
authors.forename: Leiliang
authors.initials: L
authors.lastname: He
authors.forename: Xiaohai
authors.initials: X
authors.lastname: Yang
authors.forename: Kemin
authors.initials: K
authors.lastname: Wang
authors.forename: Qing
authors.initials: Q
authors.lastname: Wang
authors.forename: Fang
authors.initials: F
authors.lastname: Zhao
authors.forename: Jin
authors.initials: J
authors.lastname: Huang
authors.forename: Jianbo
authors.initials: J
authors.lastname: Liu
mesh_terms: D004247:DNA / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D009693:Nucleic Acid Hybridization; D014466:Ultraviolet Rays
chemical_list: D004247:DNA