title: Grid cells and cortical representation.
abstract: One of the grand challenges in neuroscience is to comprehend neural computation in the association cortices, the parts of the cortex that have shown the largest expansion and differentiation during mammalian evolution and that are thought to contribute profoundly to the emergence of advanced cognition in humans. In this Review, we use grid cells in the medial entorhinal cortex as a gateway to understand network computation at a stage of cortical processing in which firing patterns are shaped not primarily by incoming sensory signals but to a large extent by the intrinsic properties of the local circuit.
authors.affiliation: Kavli Institute for Systems Neuroscience and Centre for Neural Computation, Norwegian University of Science and Technology, 7491 Trondheim, Norway.
authors.forename: Edvard I
authors.initials: EI
authors.lastname: Moser
authors.affiliation: Kavli Institute for Systems Neuroscience and Centre for Neural Computation, Norwegian University of Science and Technology, 7491 Trondheim, Norway.
authors.forename: Yasser
authors.initials: Y
authors.lastname: Roudi
authors.affiliation: Kavli Institute for Systems Neuroscience and Centre for Neural Computation, Norwegian University of Science and Technology, 7491 Trondheim, Norway.
authors.forename: Menno P
authors.initials: MP
authors.lastname: Witter
authors.affiliation: 1] Kavli Institute for Systems Neuroscience and Centre for Neural Computation, Norwegian University of Science and Technology, 7491 Trondheim, Norway. [2] Institute of Neuroscience, University of Oregon, Eugene, Oregon 97403-1254, USA.
authors.forename: Clifford
authors.initials: C
authors.lastname: Kentros
authors.affiliation: 1] Kavli Institute for Systems Neuroscience and Centre for Neural Computation, Norwegian University of Science and Technology, 7491 Trondheim, Norway. [2] Max Planck Institute of Neurobiology, Am Klopferspitz 18, 82152 Planegg-Martinsried, Germany.
authors.forename: Tobias
authors.initials: T
authors.lastname: Bonhoeffer
authors.affiliation: Kavli Institute for Systems Neuroscience and Centre for Neural Computation, Norwegian University of Science and Technology, 7491 Trondheim, Norway.
authors.forename: May-Britt
authors.initials: MB
authors.lastname: Moser
mesh_terms: D000818:Animals; D002540:Cerebral Cortex / Q000166:cytology / Q000502:physiology; D019295:Computational Biology / Q000379:methods* / Q000639:trends; D018728:Entorhinal Cortex / Q000166:cytology* / Q000502:physiology*; D006801:Humans; D009415:Nerve Net / Q000166:cytology* / Q000502:physiology*