title: A facile BPO-mediated ortho-hydroxylation and benzoylation of N-alkyl anilines for synthesis of 2-benzamidophenols.
abstract: A facile benzoyl peroxide (BPO) mediated ortho-hydroxylation and benzoylation of N-alkyl anilines for the synthesis of 2-benzamidophenols has been developed. The reaction tolerates a wide range of functional groups and is a good method for the straightforward synthesis of valuable 2-benzamidophenols in good yields under mild conditions.
authors.affiliation: Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry & Materials Science, Northwest University , Xi'an 710069, P. R. China.
authors.forename: Zhi-Jing
authors.initials: ZJ
authors.lastname: Zhang
authors.forename: Xue-Jing
authors.initials: XJ
authors.lastname: Quan
authors.forename: Zhi-Hui
authors.initials: ZH
authors.lastname: Ren
authors.forename: Yao-Yu
authors.initials: YY
authors.lastname: Wang
authors.forename: Zheng-Hui
authors.initials: ZH
authors.lastname: Guan
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry*; D001585:Benzoyl Peroxide / Q000737:chemistry*; D006900:Hydroxylation; D015394:Molecular Structure; D010636:Phenols / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000814:Aniline Compounds; D010636:Phenols; D001585:Benzoyl Peroxide