title: Physical comorbidities affect physical activity in chronic obstructive pulmonary disease: a prospective cohort study.
abstract: OBJECTIVE
  The prevalence of physical comorbidities such as obesity, musculoskeletal or neurological conditions in people with chronic obstructive pulmonary disease (COPD) is high, yet little is known about the impact of these physical comorbidities on physical activity. The primary aim of the study was to compare the physical activity levels of people with COPD with physical comorbidities (COPD + PC) to people with COPD without physical comorbidities (COPD) and healthy age-matched volunteers (control group).
  
  
  METHODS
  Twenty-five people with COPD + PC (mean (standard deviation (SD)) age 73 (11) years, Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage II-IV), 25 people with COPD (70 (8) years, GOLD stage II-IV) and 25 controls (70 (7) years) wore the SenseWear Pro3 Armband for 7 days.
  
  
  RESULTS
  Engagement in light intensity physical activity (1.5-3.0 metabolic equivalents (MET)) (140 (76) minutes per day (min/day)) and moderate intensity physical activity (3.0-6.0 MET) (25 (35) min/day) in the COPD + PC group was significantly reduced compared with the COPD (231 (76) and 104 (106), respectively) and control group (259 (75) and 114 (57), respectively). In the 16 daytime hours between 6 am and 10 pm, people with COPD + PC spent a mean (SD) of 771 (98) min/day engaged in sedentary behaviour (<1.5 MET). This was significantly greater than the group with COPD (603 (148) min/day) and the control group (567 (76) min/day) (P < 0.001).
  
  
  CONCLUSIONS
  People with COPD + PC had significantly lower daily physical activity levels compared with people with COPD without physical comorbidities and healthy people.
authors.affiliation: Clinical and Rehabilitation Sciences, University of Sydney, Sydney, New South Wales, Australia; Department of Respiratory and Sleep Medicine, Prince of Wales Hospital, Sydney, New South Wales, Australia; Department of Physiotherapy, Prince of Wales Hospital, Sydney, New South Wales, Australia.
authors.forename: Renae J
authors.initials: RJ
authors.lastname: McNamara
authors.forename: Zoe J
authors.initials: ZJ
authors.lastname: McKeough
authors.forename: David K
authors.initials: DK
authors.lastname: McKenzie
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Alison
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D015331:Cohort Studies; D015897:Comorbidity; D015444:Exercise / Q000502:physiology; D005260:Female; D005541:Forced Expiratory Volume / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D009140:Musculoskeletal Diseases / Q000453:epidemiology / Q000503:physiopathology*; D009422:Nervous System Diseases / Q000453:epidemiology / Q000503:physiopathology*; D009765:Obesity / Q000453:epidemiology / Q000503:physiopathology*; D017063:Outcome Assessment, Health Care; D011446:Prospective Studies; D029424:Pulmonary Disease, Chronic Obstructive / Q000453:epidemiology / Q000503:physiopathology*; D012720:Severity of Illness Index; D014797:Vital Capacity / Q000502:physiology
keywords: ambulatory monitoring; chronic obstructive pulmonary disease; comorbidity; sedentary lifestyle