title: Neurologic indications for therapeutic plasma exchange: 2013 update.
abstract: Neurologists commonly use therapeutic plasma exchange (TPE) to treat a number of conditions. This concise review considers the most common neurologic indications for TPE. It focuses on Guillain-Barré syndrome and myasthenia gravis and also the role of TPE in chronic inflammatory demyelinating polyneuropathy, Lambert-Eaton syndrome, multiple sclerosis, neuromyelitis optica, paraproteinemic polyneuropathy, Sydenham's chorea, and natalizumab-associated progressive multifocal leukoencephalopathy. As with any treatment, the proven efficacy, cost, side effects, and availability must be considered before initiation of therapy.
authors.affiliation: Department of Neurology, The University of Virginia, Charlottesville, Virginia.
authors.forename: Kelly
authors.initials: K
authors.lastname: Gwathmey
authors.forename: Rasheed A
authors.initials: RA
authors.lastname: Balogun
authors.forename: Ted
authors.initials: T
authors.lastname: Burns
mesh_terms: D061067:Antibodies, Monoclonal, Humanized / Q000009:adverse effects; D020274:Autoimmune Diseases of the Nervous System / Q000276:immunology / Q000628:therapy*; D003131:Combined Modality Therapy; D020820:Dyskinesias / Q000628:therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007968:Leukoencephalopathy, Progressive Multifocal / Q000139:chemically induced / Q000628:therapy; D000069442:Natalizumab; D010265:Paraproteinemias / Q000628:therapy; D010951:Plasma Exchange
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D007166:Immunosuppressive Agents; D000069442:Natalizumab
keywords: CIDP; Guillain-Barré syndrome; Lambert-Eaton syndrome; Syndenham's chorea; apheresis; myasthenia gravis; natalizumab; neurologic indications; plasmapheresis; progressive multifocal leukoencephalopathy