title: Efficacy of tigecycline, polymyxin, gentamicin, meropenem and associations in experimental Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae non-lethal sepsis.
authors.affiliation: Medicine Department, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brazil; Internal Medicine Postgraduate Programme, Universidade Federal do Paraná, Curitiba, PR, Brazil. Electronic address: paulavmtoledo@yahoo.com.br.
authors.forename: Paula Virginia Michelon
authors.initials: PV
authors.lastname: Toledo
authors.affiliation: Medicine Department, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brazil; Division of Infectious Diseases, Universidade Federal do Paraná, Curitiba, PR, Brazil; Internal Medicine Postgraduate Programme, Universidade Federal do Paraná, Curitiba, PR, Brazil.
authors.forename: Felipe Francisco
authors.initials: FF
authors.lastname: Tuon
authors.affiliation: Bacteriology Section, Laboratório Central de Saúde Pública do Estado LACEN, PR, Brazil.
authors.forename: Lavinia
authors.initials: L
authors.lastname: Arend
authors.affiliation: Medicine Department, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brazil; Surgery Postgraduate Programme, Universidade Federal do Paraná, Curitiba, PR, Brazil.
authors.forename: Ayrton Alves
authors.initials: AA
authors.lastname: Aranha Junior
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000096:biosynthesis*; D004359:Drug Therapy, Combination / Q000379:methods; D005839:Gentamicins / Q000627:therapeutic use; D007710:Klebsiella Infections / Q000188:drug therapy* / Q000382:microbiology; D007711:Klebsiella pneumoniae / Q000201:enzymology*; D000077731:Meropenem; D008911:Minocycline / Q000031:analogs & derivatives / Q000627:therapeutic use; D011113:Polymyxins / Q000627:therapeutic use; D051381:Rats; D018805:Sepsis / Q000188:drug therapy*; D013845:Thienamycins / Q000627:therapeutic use; D000078304:Tigecycline; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D001426:Bacterial Proteins; D005839:Gentamicins; D011113:Polymyxins; D013845:Thienamycins; D000078304:Tigecycline; D001618:beta-Lactamases; C063912:carbapenemase; D000077731:Meropenem; D008911:Minocycline