title: [Oral allergy syndrome in adults of a third level hospital].
abstract: BACKGROUND
  Oral allergy syndrome (OAS) is the mildest form of an allergic reaction to foods. It is characterized by the presence of IgE mediated symptoms restricted to oral mucosa after intake of fresh fruits and vegetables. OAS diagnosis is based on suggestive clinical manifestations and can be confirmed with tests such as prick-to-prick skin test with the food implicated, which have a sensitivity > 90%, specificity 30-60%, positive predictive value (PPV) of 40% and negative predictive value (NPV) > 95%.
  
  
  OBJECTIVE
  To know the prevalence of OAS in adult patients attending a third level hospital in southern Mexico City, and also describe the demographics of these patients and comorbidities more frequently associated.
  
  
  METHODS
  We studied 44 patients (40 women and 4 men), with an average age of 33.4 years, with suggestive clinical features of OAS, evaluated with prick-by-prick skin tests with fresh food.
  
  
  RESULTS
  There was a predominance of OAS in woman (91%) and a prevalence of asthma and allergic rhinitis of 54% among this population. We found that 60.4% of these patients had positive prick-by-prick skin tests, being the most frequently involved families of foods: rosaceae (60%), crustaceans (25%), musaceae (23%), actinidacea (21%), lauraceae (16%) and cucurbitaceae (16%). Only 5 patients presented adverse reactions with prick-by-prick skin tests, in 4 of the cases with grade 3 and grade 4 anaphylaxis, while testing with banana-watermelon, peach, papaya and peanut, respectively.
  
  
  CONCLUSIONS
  Oral allergy syndrome affects more women than men, the most frequent comorbidities in patients with oral allergy syndrome are allergic rhinitis and asthma, thus, in patients with asthma and allergic rhinitis, sensitized to pollens we have to ask about symptoms suggestive of oral allergy syndrome.
authors.affiliation: Servicio de Alergia e Inmunología Clínica, Hospital de Especialidades Dr. Bernardo Sepúlveda, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, DF. karen_aicila@hotmail.com.
authors.forename: Karen A
authors.initials: KA
authors.lastname: Rodríguez-Mireles
authors.forename: Arturo
authors.initials: A
authors.lastname: Gaspar-López
authors.forename: Eunice G
authors.initials: EG
authors.lastname: López-Rocha
authors.forename: Leonel
authors.initials: L
authors.lastname: Del Rivero-Hernández
authors.forename: Nora Hilda
authors.initials: NH
authors.lastname: Segura-Méndez
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005512:Food Hypersensitivity / Q000453:epidemiology / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012882:Skin Tests; D013577:Syndrome; D062606:Tertiary Care Centers; D055815:Young Adult
keywords: Associated foods; Diagnosis; Oral allergy syndrome; Pollen-food syndrome; Prevalence; Prick-by-prick test; Treatment