title: Spontaneous involution of diffuse fibrous dysplasia of paranasal sinuses.
abstract: We report the case of a 25-year-old patient, diagnosed at age 10, with diffuse fibrous dysplasia of the paranasal sinuses, an extremely rare idiopathic condition. This diagnosis is possible only by cerebral computed tomography (CT), cerebral and anterior skull base magnetic resonance imaging (MRI), and histopathology. Surgical treatment is common. This boy had mild symptoms: moderate headache in the morning that did not affect his daily activity, and rhinitis, partially responsive to medication. The neurologic examination was abnormal. Radiographs, CT, and MRI showed a diffuse mass in the paranasal sinuses which had a histopathological diagnosis of fibrous dysplasias. The family refused to refer the patient to surgery. The boy has been monitored annually for 15 years. He has remained asymptomatic without headache since age 11, with normal, general and neurologic examinations. Serial MRIs showed a spontaneous partial involution of the mass.
authors.affiliation: Department of Woman's and Child Health, University of Padua, Padua, Italy.
authors.forename: D
authors.initials: D
authors.lastname: De Carlo
authors.affiliation: Department of Woman's and Child Health, University of Padua, Padua, Italy.
authors.forename: L Dal
authors.initials: LD
authors.lastname: Zotto
authors.affiliation: Department of Neuroradiology, University-Hospital of Padua, Padua, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Carollo
authors.affiliation: Department of Human Anatomy and Physiology, University of Padua, Padua, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Porzionato
authors.affiliation: Department of Neurosurgery, University of Padua, Padua, Italy.
authors.forename: D
authors.initials: D
authors.lastname: D'Avella
authors.affiliation: Department of Radiology of Oncology Institute of Padua IOV, Padua, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Pomerri
authors.affiliation: Department of Woman's and Child Health, University of Padua, Padua, Italy pierantonio.battistella@unipd.it.
authors.forename: P A
authors.initials: PA
authors.lastname: Battistella
mesh_terms: D000328:Adult; D002648:Child; D018450:Disease Progression; D005359:Fibrous Dysplasia, Polyostotic / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D006261:Headache / Q000209:etiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010256:Paranasal Sinuses / Q000000981:diagnostic imaging* / Q000473:pathology*; D014057:Tomography, X-Ray Computed
keywords: child; fibrous dysplasia; follow-up; paranasal sinuses; spontaneous involution