title: Ga-68 Somatostatin Receptor PET/CT in von Hippel-Lindau Disease.
abstract: Von Hippel-Lindau (VHL) disease is a dominantly inherited familial cancer syndrome with a variety of benign and malignant tumors such as retinal and central nervous system hemangioblastomas, endolymphatic sac tumors, renal cysts and tumors, pancreatic cysts and tumors, pheochromocytomas, and epididymal cystadenomas. Cross-sectional modalities (computed tomography and magnetic resonance imaging) as well as ultrasound play a major role in the initial evaluation and follow-up of the various manifestations of VHL disease. Ga-68-labeled somatostatin receptor analogs already have a significant role in the diagnosis, staging, and therapy management of neuroendocrine neoplasms and neural crest tumors. Herein, we report a case presenting a variety of malignancies in VHL and showing the usefulness of Ga-68 somatostatin receptor PET/CT as a one-stop-shop imaging modality in the management of VHL disease.
authors.affiliation: Department of Nuclear Medicine, Chonnam National University Hwasun Hospital, Hwasun, South Korea.
authors.forename: Jong-Ryool
authors.initials: JR
authors.lastname: Oh
authors.affiliation: Department of Nuclear Medicine and Center for PET/CT, Zentralklinik Bad Berka, 99437 Bad Berka, Germany.
authors.forename: Harshad
authors.initials: H
authors.lastname: Kulkarni
authors.affiliation: Department of Nuclear Medicine and Center for PET/CT, Zentralklinik Bad Berka, 99437 Bad Berka, Germany.
authors.forename: Cecilia
authors.initials: C
authors.lastname: Carreras
authors.affiliation: Department of Nuclear Medicine and Center for PET/CT, Zentralklinik Bad Berka, 99437 Bad Berka, Germany.
authors.forename: Georg
authors.initials: G
authors.lastname: Schalch
authors.affiliation: Department of Nuclear Medicine, Chonnam National University Hwasun Hospital, Hwasun, South Korea.
authors.forename: Jung-Joon
authors.initials: JJ
authors.lastname: Min
authors.affiliation: Department of Nuclear Medicine and Center for PET/CT, Zentralklinik Bad Berka, 99437 Bad Berka, Germany.
authors.forename: Richard P
authors.initials: RP
authors.lastname: Baum
keywords: Ga-68 DOTA-NOC PET/CT; Ga-68 DOTA-TATE PET/CT; Ga-68 DOTA-TOC PET/CT; Hemangioblastoma; Pheochromocytoma; von Hippel-Lindau disease