title: Serum uric acid levels and metabolic syndrome.
abstract: OBJECTIVE
  To investigate the relationship among serum uric acid levels and metabolic syndrome.
  
  
  METHODS
  Anthropometric parameters, serum uric acid and metabolic parameters were evaluated in 139 subjects.
  
  
  RESULTS
  Serum uric acid levels were significantly higher in subjects with than without metabolic syndrome (p < 0.0001), and raised gradually with the increasing number of metabolic syndrome components (p for trend < 0.0001). Serum uric acid significantly correlated with various anthropometric and serum metabolic parameters.
  
  
  CONCLUSIONS
  Serum uric acid levels were higher in individuals with rather than without metabolic syndrome and raised gradually as the number of metabolic syndrome components increased. The relationship between serum uric acid levels and various metabolic parameters suggests that uric acid might be considered as a component of metabolic syndrome.
  
  
  BACKGROUND
  Hyperuricemia is a common finding in patients with the metabolic syndrome. Recent studies indicated that hyperuricemia may be also a predictor of metabolic syndrome development.
authors.affiliation: University of L'Aquila, Department of Life, Health and Environmental Sciences , San Salvatore Hospital, L'Aquila , Italy.
authors.forename: Sara
authors.initials: S
authors.lastname: Ciarla
authors.forename: Manuela
authors.initials: M
authors.lastname: Struglia
authors.forename: Paolo
authors.initials: P
authors.lastname: Giorgini
authors.forename: Rinaldo
authors.initials: R
authors.lastname: Striuli
authors.forename: Stefano
authors.initials: S
authors.lastname: Necozione
authors.forename: Giuliana
authors.initials: G
authors.lastname: Properzi
authors.forename: Claudio
authors.initials: C
authors.lastname: Ferri
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007333:Insulin Resistance; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood*; D008875:Middle Aged; D012044:Regression Analysis; D014527:Uric Acid / Q000097:blood*; D055815:Young Adult
chemical_list: D014527:Uric Acid
keywords: Cardiovascular risk; Uric acid; insulin resistance; metabolic syndrome