title: Ultrasensitive detection of ATP based on ATP regeneration amplification and its application in cell homogenate and human serum.
abstract: A conformation-switching aptamer molecule that could be circularized without ligation DNA was designed. Pyrophosphate (PPi) was converted to ATP, resulting in higher signals for ATP detection. Meanwhile, the method has significant implications for real applications.
authors.affiliation: School of Chemistry and Chemical Engineering, Linyi University, Linyi 276005, China. yingshug@126.com.
authors.forename: Yingshu
authors.initials: Y
authors.lastname: Guo
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Sun
authors.forename: Guangxu
authors.initials: G
authors.lastname: Yang
authors.forename: Jia
authors.initials: J
authors.lastname: Liu
mesh_terms: D000255:Adenosine Triphosphate / Q000032:analysis*; D052157:Aptamers, Nucleotide / Q000737:chemistry*; D015374:Biosensing Techniques / Q000379:methods; D003593:Cytoplasm / Q000737:chemistry*; D006801:Humans; D021141:Nucleic Acid Amplification Techniques / Q000379:methods / Q000592:standards*; D044967:Serum / Q000737:chemistry*
chemical_list: D052157:Aptamers, Nucleotide; D000255:Adenosine Triphosphate