title: Stereoselective Intramolecular Cyclopropanation of α-Diazoacetates via Co(II)-Based Metalloradical Catalysis.
abstract: Co(II) complexes ofD2-symmetric chiral porphyrins have been proven to be effective metalloradical catalysts for the asymmetric intramolecular cyclopropanation of allyl α-diazoacetates. 4-(Dimethylamino)pyridine (DMAP), through positivetranseffect, plays an important role in the enhancement of the asymmetric induction for the intramolecular cyclopropanation process. This metalloradical catalytic system is suitable for cyclopropanation of allyl α-diazoacetates with varied functional groups and substitution patterns, producing bicyclic products with complete diastereocontrol and good enantiocontrol.
authors.forename: Joshua V
authors.initials: JV
authors.lastname: Ruppel
authors.forename: Xin
authors.initials: X
authors.lastname: Cui
authors.forename: Xue
authors.initials: X
authors.lastname: Xu
authors.forename: X Peter
authors.initials: XP
authors.lastname: Zhang