title: Aphasia: Current Concepts in Theory and Practice.
abstract: Recent advances in neuroimaging contribute to a new insights regarding brain-behavior relationships and expand understanding of the functional neuroanatomy of language. Modern concepts of the functional neuroanatomy of language invoke rich and complex models of language comprehension and expression, such as dual stream networks. Increasingly, aphasia is seen as a disruption of cognitive processes underlying language. Rehabilitation of aphasia incorporates evidence based and person-centered approaches. Novel techniques, such as methods of delivering cortical brain stimulation to modulate cortical excitability, such as repetitive transcranial magnetic stimulation and transcranial direct current stimulation, are just beginning to be explored. In this review, we discuss the historical context of the foundations of neuroscientific approaches to language. We sample the emergent theoretical models of the neural substrates of language and cognitive processes underlying aphasia that contribute to more refined and nuanced concepts of language. Current concepts of aphasia rehabilitation are reviewed, including the promising role of cortical stimulation as an adjunct to behavioral therapy and changes in therapeutic approaches based on principles of neuroplasticity and evidence-based/person-centered practice to optimize functional outcomes.
authors.affiliation: Department of Neurology, Johns Hopkins University School of Medicine, USA.
authors.forename: Donna C
authors.initials: DC
authors.lastname: Tippett
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, School of Medicine, USA.
authors.forename: John K
authors.initials: JK
authors.lastname: Niparko
authors.affiliation: Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, USA.
authors.forename: Argye E
authors.initials: AE
authors.lastname: Hillis
keywords: aphasia; dorsal and ventral streams; neuroanatomy; rehabilitation; stroke