title: Synthesis of poly acrylic acid modified silver nanoparticles and their antimicrobial activities.
abstract: Poly acrylic acid modified silver (Ag/PAA) nanoparticles (NPs) have been successfully synthesized in the aqueous solution by using tannic acid as a reductant. The structure, morphology and composition of Ag/PAA NPs were characterized by various techniques such as X-ray powder diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), ultraviolet-visible absorption spectroscopy (UV-vis) and thermogravimetry analysis (TGA). The results show that PAA/Ag NPs have a quasi-ball shape with an average diameter of 10 nm and exhibit well crystalline, and the reaction conditions have some effect on products morphology and size distribution. In addition, the as-synthesized Ag/PAA NPs antimicrobial activities against Escherichia coli (E. coli), Pseudomonas aeruginosa (P. aeruginosa) and Staphylococcus aureus (S. aureus) were evaluated by the methods of broth dilution, cup diffusion, optical density (OD600) and electron microscopy observation. The as-synthesized Ag/PAA NPs exhibit excellent antibacterial activity. The antimicrobial mechanism may be attributed to the damaging of bacterial cell membrane and causing leakage of cytoplasm.
authors.affiliation: Key Laboratory for Special Functional Materials of Ministry of Education, Henan University, Kaifeng 475004, PR China.
authors.forename: Zhihui
authors.initials: Z
authors.lastname: Ni
authors.affiliation: Institute of Environmental and Analytical Sciences, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, PR China.
authors.forename: Zhihua
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Key Laboratory for Special Functional Materials of Ministry of Education, Henan University, Kaifeng 475004, PR China. Electronic address: sunlei@henu.edu.cn.
authors.forename: Lei
authors.initials: L
authors.lastname: Sun
authors.affiliation: Key Laboratory of Cellular and Molecular Immunology, Henan University, Kaifeng 475004, PR China.
authors.forename: Binjie
authors.initials: B
authors.lastname: Li
authors.affiliation: Key Laboratory for Special Functional Materials of Ministry of Education, Henan University, Kaifeng 475004, PR China.
authors.forename: Yanbao
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry*; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000633:toxicity; D008826:Microbial Sensitivity Tests; D010084:Oxidation-Reduction; D010316:Particle Size; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012834:Silver / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects; D013634:Tannins / Q000737:chemistry
chemical_list: D000180:Acrylic Resins; D000890:Anti-Infective Agents; D013634:Tannins; D012834:Silver; C006903:carbopol 940
keywords: Antimicrobial property; Poly acrylic acid; Silver nanoparticles; Synthesis