title: Switchable reconfiguration of an interlocked DNA olympiadane nanostructure.
abstract: Interlocked DNA rings (catenanes) are interesting reconfigurable nanostructures. The synthesis of catenanes with more than two rings is, however, hampered, owing to low yields of these systems. We report a new method for the synthesis of catenanes with a controlled number of rings in satisfactory yields. Our approach is exemplified by the synthesis of a five-ring DNA catenane that exists in four different configurations. By the use of nucleic acids as "fuels" and "antifuels", the cyclic reconfiguration of the system across four states is demonstrated. One of the states, olympiadane, corresponds to the symbol of the Olympic Games. The five-ring catenane was implemented as a mechanical scaffold for the reconfiguration of Au NPs. The advantages of DNA catenanes over supramolecular catenanes include the possibility of generating highly populated defined states and the feasibility of tethering nanoobjects to the catenanes, which act as a mechanical scaffold to reconfigure the nanoobjects.
authors.affiliation: Institute of Chemistry and The Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 91904 (Israel).
authors.forename: Chun-Hua
authors.initials: CH
authors.lastname: Lu
authors.forename: Xiu-Juan
authors.initials: XJ
authors.lastname: Qi
authors.forename: Alessandro
authors.initials: A
authors.lastname: Cecconello
authors.forename: Stefan-Sven
authors.initials: SS
authors.lastname: Jester
authors.forename: Michael
authors.initials: M
authors.lastname: Famulok
authors.forename: Itamar
authors.initials: I
authors.lastname: Willner
mesh_terms: D004247:DNA / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D049329:Nanostructures
chemical_list: D004247:DNA
keywords: DNA catenanes; molecular devices; nanoparticles; strand displacement; switches