title: New therapies for coronary artery disease: genetics provides a blueprint.
abstract: The development of new therapies for coronary artery disease (CAD) poses a substantial challenge, and several recent approaches have failed for lack of efficacy. Human genetics has the potential to identify new targets for which the likelihood of therapeutic success is considerably greater. The intense focus on the genetics of CAD will revitalize the field and lead to future therapies for this common disease.
authors.affiliation: Department of Medicine and Department of Genetics, Cardiovascular Institute, and Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Rader
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D003324:Coronary Artery Disease / Q000235:genetics* / Q000628:therapy*; D006801:Humans; D058990:Molecular Targeted Therapy
chemical_list: D015415:Biomarkers