title: First identification and quantification of lorcaserin in an herbal slimming dietary supplement.
abstract: The weight-loss drug lorcaserin, a FDA approved anorectic drug, was isolated from the dietary supplement "Lose quickly" claimed to be a pure natural fast slimming diet pill. After its purification by means of preparative liquid chromatography, its structure was characterized using LC-UV, NMR, MS, MS/MS, and IR spectroscopy. The amount of lorcaserin measured by qNMR was 6.6mg/capsule.
authors.affiliation: Groupe de RMN Biomédicale, Laboratoire SPCMIB (UMR CNRS 5068), Université Paul Sabatier, Université de Toulouse, 118 route de Narbonne, 31062 Toulouse cedex, France.
authors.forename: Rabab
authors.initials: R
authors.lastname: Hachem
authors.affiliation: Groupe de RMN Biomédicale, Laboratoire SPCMIB (UMR CNRS 5068), Université Paul Sabatier, Université de Toulouse, 118 route de Narbonne, 31062 Toulouse cedex, France.
authors.forename: Myriam
authors.initials: M
authors.lastname: Malet-Martino
authors.affiliation: Groupe de RMN Biomédicale, Laboratoire SPCMIB (UMR CNRS 5068), Université Paul Sabatier, Université de Toulouse, 118 route de Narbonne, 31062 Toulouse cedex, France. Electronic address: gilard@chimie.ups-tlse.fr.
authors.forename: Véronique
authors.initials: V
authors.lastname: Gilard
mesh_terms: D001552:Benzazepines / Q000737:chemistry*; D002853:Chromatography, Liquid / Q000379:methods; D019587:Dietary Supplements / Q000032:analysis*; D029001:Herbal Medicine / Q000379:methods; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D053719:Tandem Mass Spectrometry / Q000379:methods
chemical_list: D001552:Benzazepines; C506658:lorcaserin
keywords: Adulteration; Lorcaserin; Mass Spectrometry (MS); Nuclear Magnetic Resonance (NMR); Slimming dietary supplements