title: Selective neurolysis in post-paralytic facial nerve syndrome (PFS).
abstract: Post-paralytic facial nerve syndrome (PFS) summarizes specific symptoms that result from an incomplete or poor recovery of the facial nerve after peripheral facial palsy. Selective chemodenervation using botulinum toxin A (Btx A) and mime therapy represent the therapeutic standard for treating PFS. We report on a 35-year-old male who was suffering greatly from unilateral PFS-specific movement disorders, including periorbital contractions and oculofacial synkinesis that did not respond to Btx A administration. We present a surgical alternative to overcome periorbital movement disorders by selective neurolysis and review therapeutic options for this rare syndrome. In conclusion, selective neurolysis appears to be an efficient alternative treatment method of PFS in which the quality of life is severely impacted due to movement disorders and there was no therapeutic benefit from Btx A.
  
  
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authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Center for Plastic and Reconstructive Head and Neck Surgery, Dr. Horst Schmidt Kliniken, Ludwig-Erhard-Straße 100, 65199, Wiesbaden, Germany, gregor.bran@hsk-wiesbaden.de.
authors.forename: Gregor M
authors.initials: GM
authors.lastname: Bran
authors.forename: Peter J F M
authors.initials: PJ
authors.lastname: Lohuis
mesh_terms: D000328:Adult; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use; D003286:Contracture / Q000601:surgery; D005158:Facial Paralysis / Q000601:surgery*; D005546:Forehead / Q000294:innervation / Q000601:surgery; D006801:Humans; D008297:Male; D009407:Nerve Block; D009465:Neuromuscular Agents / Q000627:therapeutic use; D009801:Oculomotor Muscles / Q000601:surgery; D011183:Postoperative Complications / Q000601:surgery; D011788:Quality of Life; D013577:Syndrome; D046608:Synkinesis / Q000601:surgery*; D017211:Treatment Failure
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A