title: A single aspergillus fumigatus intracranial abscess in an immunocompetent patient with parietal lobe tumorectomy.
abstract: Aspergillosis of the central nervous system is a rare fungal infection that is mainly reported in patients with immune deficiency, such as AIDS patients and organ transplant patients treated with immunosuppressive agents, and is uncommon among patients with intact immune function. We report here a rare case of intracranial aspergillosis in a patient who had previously undergone a parietal lobe tumorectomy. Aspergillus fumigatus was confirmed by histopathology, and susceptibility tests reported that this infection should respond to voriconazole. We believe the immunosuppression resulting from surgical trauma and glucocorticosteroid treatment may be contributing to the infection, and therefore management of these two factors may improve the prognosis.
authors.forename: Zhao-Shi
authors.initials: ZS
authors.lastname: Bao
authors.forename: Gan
authors.initials: G
authors.lastname: You
authors.forename: Wen-Bin
authors.initials: WB
authors.lastname: Li
authors.affiliation: Beijing Neurosurgical Institute, Beijing 100050, China. taojiang1964@163.com.
authors.forename: Tao
authors.initials: T
authors.lastname: Jiang
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000188:drug therapy / Q000382:microbiology*; D001232:Aspergillus fumigatus / Q000302:isolation & purification*; D001922:Brain Abscess / Q000188:drug therapy / Q000382:microbiology*; D001932:Brain Neoplasms / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007121:Immunocompetence; D008297:Male; D008826:Microbial Sensitivity Tests; D010296:Parietal Lobe / Q000473:pathology / Q000601:surgery*; D011183:Postoperative Complications; D011379:Prognosis; D065819:Voriconazole / Q000627:therapeutic use
chemical_list: D000935:Antifungal Agents; D065819:Voriconazole