title: Sialoendoscopy: a viable treatment for I(131) induced sialoadenitis.
abstract: To evaluate the viability, efficacy, and safety of sialoendoscopy for the diagnosis and management of radioiodine I(131-) related sialoadenitis, we retrospectively reviewed 30 patients referred between September 2007 and July 2013 from the Thyroid Surgery Unit to the Maxillofacial Unit of the Second University of Naples Hospital with persistent sialoadenitis after treatment with I(131). After the affected gland had been isolated, the endoscope was introduced into the duct under local anaesthesia with 2% lignocaine and continuous lavage with isotonic saline, and was advanced until it reached the ductal system. We studied 24 women and 6 men, mean (SD) age 52 (??) years. In 25 patients I(131) was given for papillary (83%), in 3 for medullary (10%), and in 2 for follicular thyroid carcinoma (7%). Stenosis alone was found in 30 glands (40%), mucous plugs alone in 35 (47%), and mucous plugs, stenosis, and kinks in 10 (13%). Of the 75 glands, dilatation of the ducts was successful in 70, and we completely removed all mucous plugs and kinks. We achieved symptomatic improvement in 23 patients (77%) during a follow-up ranging from 2 weeks to 84 months. Sialoendoscopy is a viable technique for the diagnosis of obstructive salivary disease, and is a safe and effective way to treat sialoadenitis, the most common complication of treatment with I(131).
authors.affiliation: Dipartimento Multidisciplinare di Specialità Medico-chirurgiche ed Odontoiatriche, Seconda Università degli Studi di Napoli. Electronic address: sifilide89@gmail.com.
authors.forename: R
authors.initials: R
authors.lastname: De Luca
authors.affiliation: Dipartimento Multidisciplinare di Specialità Medico-chirurgiche ed Odontoiatriche, Seconda Università degli Studi di Napoli.
authors.forename: A
authors.initials: A
authors.lastname: Vicidomini
authors.affiliation: Dipartimento Multidisciplinare di Specialità Medico-chirurgiche ed Odontoiatriche, Seconda Università degli Studi di Napoli.
authors.forename: M
authors.initials: M
authors.lastname: Trodella
authors.affiliation: Dipartimento Multidisciplinare di Specialità Medico-chirurgiche ed Odontoiatriche, Seconda Università degli Studi di Napoli.
authors.forename: G
authors.initials: G
authors.lastname: Tartaro
authors.affiliation: Dipartimento Multidisciplinare di Specialità Medico-chirurgiche ed Odontoiatriche, Seconda Università degli Studi di Napoli.
authors.forename: G
authors.initials: G
authors.lastname: Colella
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000532:radiotherapy; D000328:Adult; D000368:Aged; D018276:Carcinoma, Medullary / Q000532:radiotherapy; D003251:Constriction, Pathologic / Q000209:etiology / Q000628:therapy; D004106:Dilatation / Q000379:methods; D004724:Endoscopy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007457:Iodine Radioisotopes / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009093:Mucus; D010309:Parotitis / Q000209:etiology / Q000628:therapy; D019275:Radiopharmaceuticals / Q000009:adverse effects*; D012189:Retrospective Studies; D018987:Salivary Ducts / Q000473:pathology; D012793:Sialadenitis / Q000209:etiology / Q000628:therapy*; D013364:Submandibular Gland Diseases / Q000209:etiology / Q000628:therapy; D007507:Therapeutic Irrigation / Q000379:methods; D013964:Thyroid Neoplasms / Q000532:radiotherapy; D016896:Treatment Outcome
chemical_list: D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals
keywords: I 131 induced sialoadenitis; Imaging in salivary diseases; Sialoendoscopy