title: The reliability of a novel magnetic resonance imaging-based tool for the evaluation of forefoot bursae in patients with rheumatoid arthritis: the FFB score.
abstract: OBJECTIVE
  The aim of this study was to determine the reliability of an MRI-based score that evaluates forefoot bursae (FFBs) in patients with RA.
  
  
  METHODS
  Items for inclusion, grading criteria and MRI sequences were determined iteratively. The score was evaluated in 30 patients with established RA. Reader agreement was evaluated using the percentage of exact/close agreement, Bland-Altman plots, kappa and intraclass correlation coefficient analyses.
  
  
  RESULTS
  The FFB score assesses nine forefoot regions and contains four items: presence, shape, enhancement and magnetic resonance characteristics. The FFB score showed moderate to good intra- and interreader agreement (κ range = 0.5-0.9 and 0.47-0.87, respectively).
  
  
  CONCLUSIONS
  The FFB score is adequately reliable in the evaluation of bursa-like lesions of the forefoot in patients with RA.
authors.affiliation: Faculty of Health Sciences, University of Southampton, Department of Podiatry, Solent NHS Trust, Department of Radiology, University Hospital Southampton NHS Foundation Trust, Southampton, UK, Department of Radiology, Klinikum Augsburg, Augsburg, Germany, Department of Radiology, Boston University, Boston, MA, USA, Faculty of Medicine, University of Southampton, Southampton, Nuffield Department of Orthopaedics and Rheumatology, University of Oxford, Oxford and NIHR-Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK. Faculty of Health Sciences, University of Southampton, Department of Podiatry, Solent NHS Trust, Department of Radiology, University Hospital Southampton NHS Foundation Trust, Southampton, UK, Department of Radiology, Klinikum Augsburg, Augsburg, Germany, Department of Radiology, Boston University, Boston, MA, USA, Faculty of Medicine, University of Southampton, Southampton, Nuffield Department of Orthopaedics and Rheumatology, University of Oxford, Oxford and NIHR-Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK. l.cherry@soton.ac.uk.
authors.forename: Lindsey
authors.initials: L
authors.lastname: Cherry
authors.affiliation: Faculty of Health Sciences, University of Southampton, Department of Podiatry, Solent NHS Trust, Department of Radiology, University Hospital Southampton NHS Foundation Trust, Southampton, UK, Department of Radiology, Klinikum Augsburg, Augsburg, Germany, Department of Radiology, Boston University, Boston, MA, USA, Faculty of Medicine, University of Southampton, Southampton, Nuffield Department of Orthopaedics and Rheumatology, University of Oxford, Oxford and NIHR-Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
authors.forename: Leonard
authors.initials: L
authors.lastname: King
authors.affiliation: Faculty of Health Sciences, University of Southampton, Department of Podiatry, Solent NHS Trust, Department of Radiology, University Hospital Southampton NHS Foundation Trust, Southampton, UK, Department of Radiology, Klinikum Augsburg, Augsburg, Germany, Department of Radiology, Boston University, Boston, MA, USA, Faculty of Medicine, University of Southampton, Southampton, Nuffield Department of Orthopaedics and Rheumatology, University of Oxford, Oxford and NIHR-Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
authors.forename: Matthew
authors.initials: M
authors.lastname: Thomas
authors.affiliation: Faculty of Health Sciences, University of Southampton, Department of Podiatry, Solent NHS Trust, Department of Radiology, University Hospital Southampton NHS Foundation Trust, Southampton, UK, Department of Radiology, Klinikum Augsburg, Augsburg, Germany, Department of Radiology, Boston University, Boston, MA, USA, Faculty of Medicine, University of Southampton, Southampton, Nuffield Department of Orthopaedics and Rheumatology, University of Oxford, Oxford and NIHR-Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK. Faculty of Health Sciences, University of Southampton, Department of Podiatry, Solent NHS Trust, Department of Radiology, University Hospital Southampton NHS Foundation Trust, Southampton, UK, Department of Radiology, Klinikum Augsburg, Augsburg, Germany, Department of Radiology, Boston University, Boston, MA, USA, Faculty of Medicine, University of Southampton, Southampton, Nuffield Department of Orthopaedics and Rheumatology, University of Oxford, Oxford and NIHR-Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
authors.forename: Frank
authors.initials: F
authors.lastname: Roemer
authors.affiliation: Faculty of Health Sciences, University of Southampton, Department of Podiatry, Solent NHS Trust, Department of Radiology, University Hospital Southampton NHS Foundation Trust, Southampton, UK, Department of Radiology, Klinikum Augsburg, Augsburg, Germany, Department of Radiology, Boston University, Boston, MA, USA, Faculty of Medicine, University of Southampton, Southampton, Nuffield Department of Orthopaedics and Rheumatology, University of Oxford, Oxford and NIHR-Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK. Faculty of Health Sciences, University of Southampton, Department of Podiatry, Solent NHS Trust, Department of Radiology, University Hospital Southampton NHS Foundation Trust, Southampton, UK, Department of Radiology, Klinikum Augsburg, Augsburg, Germany, Department of Radiology, Boston University, Boston, MA, USA, Faculty of Medicine, University of Southampton, Southampton, Nuffield Department of Orthopaedics and Rheumatology, University of Oxford, Oxford and NIHR-Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
authors.forename: David
authors.initials: D
authors.lastname: Culliford
authors.affiliation: Faculty of Health Sciences, University of Southampton, Department of Podiatry, Solent NHS Trust, Department of Radiology, University Hospital Southampton NHS Foundation Trust, Southampton, UK, Department of Radiology, Klinikum Augsburg, Augsburg, Germany, Department of Radiology, Boston University, Boston, MA, USA, Faculty of Medicine, University of Southampton, Southampton, Nuffield Department of Orthopaedics and Rheumatology, University of Oxford, Oxford and NIHR-Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK. Faculty of Health Sciences, University of Southampton, Department of Podiatry, Solent NHS Trust, Department of Radiology, University Hospital Southampton NHS Foundation Trust, Southampton, UK, Department of Radiology, Klinikum Augsburg, Augsburg, Germany, Department of Radiology, Boston University, Boston, MA, USA, Faculty of Medicine, University of Southampton, Southampton, Nuffield Department of Orthopaedics and Rheumatology, University of Oxford, Oxford and NIHR-Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
authors.forename: Catherine J
authors.initials: CJ
authors.lastname: Bowen
authors.affiliation: Faculty of Health Sciences, University of Southampton, Department of Podiatry, Solent NHS Trust, Department of Radiology, University Hospital Southampton NHS Foundation Trust, Southampton, UK, Department of Radiology, Klinikum Augsburg, Augsburg, Germany, Department of Radiology, Boston University, Boston, MA, USA, Faculty of Medicine, University of Southampton, Southampton, Nuffield Department of Orthopaedics and Rheumatology, University of Oxford, Oxford and NIHR-Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK. Faculty of Health Sciences, University of Southampton, Department of Podiatry, Solent NHS Trust, Department of Radiology, University Hospital Southampton NHS Foundation Trust, Southampton, UK, Department of Radiology, Klinikum Augsburg, Augsburg, Germany, Department of Radiology, Boston University, Boston, MA, USA, Faculty of Medicine, University of Southampton, Southampton, Nuffield Department of Orthopaedics and Rheumatology, University of Oxford, Oxford and NIHR-Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
authors.forename: Nigel K
authors.initials: NK
authors.lastname: Arden
authors.affiliation: Faculty of Health Sciences, University of Southampton, Department of Podiatry, Solent NHS Trust, Department of Radiology, University Hospital Southampton NHS Foundation Trust, Southampton, UK, Department of Radiology, Klinikum Augsburg, Augsburg, Germany, Department of Radiology, Boston University, Boston, MA, USA, Faculty of Medicine, University of Southampton, Southampton, Nuffield Department of Orthopaedics and Rheumatology, University of Oxford, Oxford and NIHR-Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK. Faculty of Health Sciences, University of Southampton, Department of Podiatry, Solent NHS Trust, Department of Radiology, University Hospital Southampton NHS Foundation Trust, Southampton, UK, Department of Radiology, Klinikum Augsburg, Augsburg, Germany, Department of Radiology, Boston University, Boston, MA, USA, Faculty of Medicine, University of Southampton, Southampton, Nuffield Department of Orthopaedics and Rheumatology, University of Oxford, Oxford and NIHR-Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Edwards
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001172:Arthritis, Rheumatoid / Q000175:diagnosis*; D002061:Bursa, Synovial / Q000473:pathology*; D003430:Cross-Sectional Studies; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D005545:Forefoot, Human / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D055815:Young Adult
keywords: disease activity; foot; inflammation; magnetic resonance imaging; outcome measures; radiology; rheumatoid arthritis; synovium