title: Improvement in the postoperative course of salvage esophagectomy after definitive chemoradiotherapy.
abstract: OBJECTIVE
  The aim of this study was to assess the outcome of salvage esophagectomy with less extensive lymphadenectomy, which we have performed since 2003 to improve high mortality and morbidity of standard salvage esophagectomy.
  
  
  METHODS
  We retrospectively compared the surgical outcome of 15 patients who underwent standard salvage esophagectomy via right thoracotomy for thoracic esophageal cancer between 1993 and 2002 (earlier period) with the results of 11 patients between 2003 and 2011 (later period).
  
  
  RESULTS
  There were two mortalities in the earlier period, whereas no patient died in the later period, and there was a lower rate of morbidity. In the later period, there was a significantly shorter SIRS duration, lower CRP on postoperative days 1-5, and higher lymphocyte count on postoperative days 2-4. Long-term survival showed no significant difference between the two periods.
  
  
  CONCLUSIONS
  Salvage esophagectomy with less extensive lymphadenectomy might improve the surgical outcome while maintaining long-term survival.
authors.forename: Takuya
authors.initials: T
authors.lastname: Sato
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Nakamura
authors.forename: Masaho
authors.initials: M
authors.lastname: Ota
authors.forename: Kosuke
authors.initials: K
authors.lastname: Narumiya
authors.forename: Masakazu
authors.initials: M
authors.lastname: Yamamoto
mesh_terms: D000368:Aged; D059248:Chemoradiotherapy; D004938:Esophageal Neoplasms / Q000473:pathology / Q000628:therapy*; D016629:Esophagectomy; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications; D016879:Salvage Therapy; D015996:Survival Rate; D016896:Treatment Outcome