title: A molecular transport medium for collection, inactivation, transport, and detection of Mycobacterium tuberculosis.
abstract: In many parts of the world, the diagnosis of tuberculosis (TB) has rapidly shifted to molecular detection and sequencing formats. The collection and transport of Mycobacterium tuberculosis specimens thus remains a challenging problem where TB is common and the infrastructure required for ensuring sample integrity is lacking. PrimeStore(®) Molecular Transport Medium (MTM) addresses this problem, rapidly inactivating/killing M. tuberculosis while preserving genomic DNA even at elevated temperatures for subsequent downstream molecular analysis.
authors.affiliation: <label>*</label>Longhorn Vaccines & Diagnostics, San Antonio, Texas.
authors.forename: L T
authors.initials: LT
authors.lastname: Daum
authors.affiliation: <label><sup>†</sup></label>Battelle, Columbus, Ohio.
authors.forename: Y
authors.initials: Y
authors.lastname: Choi
authors.affiliation: <label>*</label>Longhorn Vaccines & Diagnostics, San Antonio, Texas.
authors.forename: S A
authors.initials: SA
authors.lastname: Worthy
authors.affiliation: <label>*</label>Longhorn Vaccines & Diagnostics, San Antonio, Texas.
authors.forename: J D
authors.initials: JD
authors.lastname: Rodriguez
authors.affiliation: <label><sup>‡</sup></label>University of Texas at San Antonio, San Antonio, Texas, USA.
authors.forename: J P
authors.initials: JP
authors.lastname: Chambers
authors.affiliation: <label>*</label>Longhorn Vaccines & Diagnostics, San Antonio, Texas.
authors.forename: G W
authors.initials: GW
authors.lastname: Fischer
mesh_terms: D001431:Bacteriological Techniques / Q000379:methods; D004269:DNA, Bacterial / Q000302:isolation & purification; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification*; D013048:Specimen Handling / Q000379:methods*; D013696:Temperature; D014376:Tuberculosis / Q000175:diagnosis* / Q000382:microbiology
chemical_list: D004269:DNA, Bacterial