title: Regulating microtubules and genome stability via the CUL7/3M syndrome complex and CUL9.
abstract: In this issue, two studies from Yue Xiong and colleagues (Li et al., 2014; Yan et al., 2014) show that CUL7, OBSL1, and CCDC8, all mutated in 3M short stature syndrome, form a centrosomal complex that regulates CUL9 and its substrate survivin to link mitosis to cell survival.
authors.affiliation: Baxter Laboratory for Stem Cell Biology, Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: pjackson@stanford.edu.
authors.forename: Peter K
authors.initials: PK
authors.lastname: Jackson