title: Comparison of frequency and severity of longitudinal stent deformation among various drug-eluting stents: an intravascular ultrasound study.
abstract: BACKGROUND
  Longitudinal stent deformation (LSD) in drug-eluting stents (DES) has been described as a disruption of stent structure. This study aimed to compare first- versus second-generation DES with respect to their actual stent length post deployment.
  
  
  METHODS
  A total of 617 DES for de novo coronary lesions in 552 patients were analyzed. Intravascular ultrasound (IVUS) was utilized to compare the degree and rate of LSD among six different DES types. IVUS-measured stent length was compared to the labeled length for calculation of absolute difference in stent length and relative absolute difference (absolute difference divided by the labeled length).
  
  
  RESULTS
  The baseline characteristics were comparable between groups, except for higher calcification in the sirolimus-eluting stent (SES) group (p=0.037). The absolute and relative difference in length showed the lowest degree in the SES group and the highest degree in the Endeavor zotarolimus-eluting stent group (p=0.085 and 0.078, respectively). The percentage of more than 5% relative absolute difference was the lowest in the SES group compared to the other groups (p=0.018). However, the percentage of significant (>15%) relative absolute difference was similar among groups (p=0.99). In multivariate linear regression analysis, labeled stent length and stent diameter, but not stent type, were identified as independent correlates to the absolute and relative difference in the actual stent length post-deployment.
  
  
  CONCLUSIONS
  This IVUS analysis confirms that among second-generation DES, there is overall similar frequency and severity of LSD when deploying in common coronary lesions.
authors.affiliation: Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Ota
authors.affiliation: Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States.
authors.forename: Hironori
authors.initials: H
authors.lastname: Kitabata
authors.affiliation: Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States.
authors.forename: Marco A
authors.initials: MA
authors.lastname: Magalhaes
authors.affiliation: Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States.
authors.forename: Anh
authors.initials: A
authors.lastname: Bui
authors.affiliation: Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States.
authors.forename: Karina
authors.initials: K
authors.lastname: Kardenas
authors.affiliation: Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States.
authors.forename: Caitlin H
authors.initials: CH
authors.lastname: Thomas
authors.affiliation: Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States.
authors.forename: Fang
authors.initials: F
authors.lastname: Chen
authors.affiliation: Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Torguson
authors.affiliation: Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States.
authors.forename: Lowell F
authors.initials: LF
authors.lastname: Satler
authors.affiliation: Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States.
authors.forename: Augusto D
authors.initials: AD
authors.lastname: Pichard
authors.affiliation: Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States. Electronic address: ron.waksman@medstar.net.
authors.forename: Ron
authors.initials: R
authors.lastname: Waksman
mesh_terms: D000368:Aged; D015331:Cohort Studies; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000628:therapy; D054855:Drug-Eluting Stents / Q000009:adverse effects* / Q000592:standards; D004868:Equipment Failure; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D012042:Registries; D012189:Retrospective Studies; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional / Q000379:methods*
keywords: Drug-eluting stent; Intravascular ultrasound; Longitudinal stent deformation