title: Validation of the Apnea Risk Evaluation System (ARES) device against laboratory polysomnography in pregnant women at risk for obstructive sleep apnea syndrome.
abstract: OBJECTIVE
  To assess the validity of using the Apnea Risk Evaluation System (ARES) Unicorder for detecting obstructive sleep apnea (OSA) in pregnant women.
  
  
  METHODS
  Sixteen pregnant women, mean age (SD) = 29.8 (5.4) years, average gestational age (SD) = 28.6 (6.3) weeks, mean body mass index (SD) = 44.7 (6.9) kg/m(2) with signs and symptoms of OSA wore the ARES Unicorder during one night of laboratory polysomnography (PSG). PSG was scored according to AASM 2007 criteria, and PSG AHI and RDI were compared to the ARES 1%, 3%, and 4% AHIs calculated with the ARES propriety software.
  
  
  RESULTS
  Median PSG AHI and PSG RDI were 3.1 and 10.3 events/h of sleep, respectively. Six women had a PSG AHI ≥ 5 events/h of sleep and 11 had a PSG RDI ≥ 5 events/h of sleep. PSG AHI and RDI were strongly correlated with the ARES AHI measures. When compared with polysomnographic diagnosis of OSA, the ARES 3% algorithm provided the best balance between sensitivity (1.0 for PSG AHI, 0.91 for PSG RDI) and specificity (0.5 for PSG AHI, 0.8 for PSG RDI) for detecting sleep disordered breathing in our sample.
  
  
  CONCLUSIONS
  The ARES Unicorder demonstrated reasonable consistency with PSG for diagnosing OSA in this small, heterogeneous sample of obese pregnant women.
authors.affiliation: Department of Medicine, Alpert Medical School of Brown University, Providence, RI ; Department of Psychiatry & Human Behavior, Alpert Medical School of Brown University, Providence, RI ; Sleep Disorders Center of Lifespan Hospitals, Providence, RI.
authors.forename: Katherine M
authors.initials: KM
authors.lastname: Sharkey
authors.affiliation: Department of Neurology, Alpert Medical School of Brown University, Providence, RI.
authors.forename: Kelly
authors.initials: K
authors.lastname: Waters
authors.affiliation: Department of Medicine, Alpert Medical School of Brown University, Providence, RI ; Sleep Disorders Center of Lifespan Hospitals, Providence, RI.
authors.forename: Richard P
authors.initials: RP
authors.lastname: Millman
authors.affiliation: Sleep Disorders Center of Lifespan Hospitals, Providence, RI.
authors.forename: Robin
authors.initials: R
authors.lastname: Moore
authors.affiliation: Women's Medicine Collaborative of Lifespan, Providence, RI.
authors.forename: Susan M
authors.initials: SM
authors.lastname: Martin
authors.affiliation: Department of Medicine, Alpert Medical School of Brown University, Providence, RI ; Women's Medicine Collaborative of Lifespan, Providence, RI.
authors.forename: Ghada
authors.initials: G
authors.lastname: Bourjeily
mesh_terms: D000328:Adult; D001921:Brain / Q000503:physiopathology; D004569:Electroencephalography / Q000295:instrumentation / Q000379:methods*; D005260:Female; D006801:Humans; D017286:Polysomnography; D011247:Pregnancy; D012307:Risk Factors; D012891:Sleep Apnea Syndromes / Q000175:diagnosis / Q000503:physiopathology; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D055815:Young Adult
keywords: ARES; obstructive sleep apnea; polysomnography; pregnancy