title: Atypical neuroimaging in Wilson's disease.
abstract: Wilson's disease is a rare metabolic disease involving copper metabolism. Neuroimaging plays an important part in evaluation of patients with a neuropsychiatric presentation. We present a case of a 14-year-old girl with atypical confluent white matter disease and cystic degeneration on MRI, with a rapidly progressive course, who succumbed to complications despite treatment with trientine. Wilson's disease should be considered as a differential for leucoencephalopathy in young patients with progressive neurological disease for its early recognition and optimum outcome.
authors.affiliation: Department of Medicine, Medical College Baroda, Vadodara, India.
authors.forename: Rushad
authors.initials: R
authors.lastname: Patell
authors.affiliation: Department of Medicine, Medical College Baroda, Vadodara, India.
authors.forename: Rupal
authors.initials: R
authors.lastname: Dosi
authors.affiliation: Department of Medicine, Medical College Baroda, Vadodara, India.
authors.forename: Harshal K
authors.initials: HK
authors.lastname: Joshi
authors.affiliation: Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
authors.forename: Dennis
authors.initials: D
authors.lastname: Storz
mesh_terms: D000293:Adolescent; D001921:Brain / Q000473:pathology*; D005260:Female; D006527:Hepatolenticular Degeneration / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D056784:Leukoencephalopathies / Q000175:diagnosis* / Q000209:etiology; D008279:Magnetic Resonance Imaging