title: Concise stereoselective total synthesis of (+)-muricatacin and (+)-epi-muricatacin.
abstract: Efficient stereoselective total synthesis of (+)-muricatacin (1) and (+)-epi-muricatacin (8) was accomplished from commercially available chemical pent-4-ynoic acid via Shi's asymmetric epoxidation and Mitsunobu reaction as the key steps in 17.8% and 26.9% overall yields, respectively.
authors.affiliation: a Department of Applied Chemistry , College of Sciences, China Agricultural University , Beijing 100193 , China.
authors.forename: Hong-Bo
authors.initials: HB
authors.lastname: Dong
authors.forename: Ming-Yan
authors.initials: MY
authors.lastname: Yang
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.forename: Ming-An
authors.initials: MA
authors.lastname: Wang
mesh_terms: D005231:Fatty Acids, Unsaturated / Q000737:chemistry; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D005231:Fatty Acids, Unsaturated; D005663:Furans; C082488:muricatacin; C003879:4-pentynoic acid
keywords: (+)-epi-muricatacin; (+)-muricatacin; asymmetric epoxidation; total synthesis