title: Review of plants and their constituents in the therapy of cerebral ischemia.
abstract: Cerebral ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. This leads to cerebral hypoxia and thus to the death of neuronal cells or stroke. The limited number of medicines currently available for patients following ischemic stroke and insufficient data on efficiency of these chemicals in the treatment of stroke led us to the search for novel therapeutic approaches. Recent studies have focused on the possible capacity of natural compounds extracted from vegetables and fruits, to prevent human disabilities caused by cerebral ischemia. In this review, we will discuss some plants and their constituents that may protect brain ischemia or delay the neurological disorders following a stroke. We have reviewed different studies in scientific databases that investigate herbal compounds and their effects on cerebral ischemia.
authors.affiliation: Department of Pharmacodynamy and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Effat
authors.initials: E
authors.lastname: Behravan
authors.forename: Bibi Marjan
authors.initials: BM
authors.lastname: Razavi
authors.forename: Hossein
authors.initials: H
authors.lastname: Hosseinzadeh
mesh_terms: D000818:Animals; D002545:Brain Ischemia / Q000188:drug therapy*; D006801:Humans; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D020521:Stroke / Q000188:drug therapy*
keywords: cerebral ischemia; herbs; plants; stroke