title: Mixed Nipple Infections Caused by Variant of BPV3 and a Putative New Subtype of BPV in Cattle.
abstract: Bovine papilloma is a chronic and proliferative skin and mucosal wart caused by Bovine papillomavirus (BPV). In June, 2013, a leaf-and flat-shaped wart disease was observed on the nipple skins in a cattle farm in Xinjiang. To diagnose the disease, we collected the diseased skins for pathological biopsy and DNA analysis by PCR amplification using a pair of degenerate primers FAP59 and FAP64. Sequencing and phylogenetic analysis showed that the infection was caused by a variant of BPV3 and putatively a new subtype of BPV (BPV/CHI-SW1, belonging to the Xi papillomavirus genus). This is the first report of mixed infection caused by variant of BPV3 and BPV (putatively new subtype) in China, and would be of importance for the molecular epidemiological study of the disease.
authors.affiliation: College of Animal Science and Technology, Shihezi University, Shihezi, China.
authors.forename: Z
authors.initials: Z
authors.lastname: He
authors.affiliation: College of Animal Science and Technology, Shihezi University, Shihezi, China.
authors.forename: Q
authors.initials: Q
authors.lastname: Meng
authors.affiliation: College of Animal Science and Technology, Shihezi University, Shihezi, China.
authors.forename: J
authors.initials: J
authors.lastname: Qiao
authors.affiliation: College of Animal Science and Technology, Shihezi University, Shihezi, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Peng
authors.affiliation: College of Animal Science and Technology, Shihezi University, Shihezi, China.
authors.forename: K
authors.initials: K
authors.lastname: Xie
authors.affiliation: College of Animal Science and Technology, Shihezi University, Shihezi, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.
authors.forename: X
authors.initials: X
authors.lastname: Cai
authors.affiliation: Veterinary Station of Shawan County, Xinjiang, China.
authors.forename: J
authors.initials: J
authors.lastname: Zhang
authors.affiliation: College of Animal Science and Technology, Shihezi University, Shihezi, China.
authors.forename: C
authors.initials: C
authors.lastname: Chen
mesh_terms: D000818:Animals; D001941:Breast Diseases / Q000662:veterinary* / Q000821:virology; D002417:Cattle; D002418:Cattle Diseases / Q000821:virology*; D002681:China; D060085:Coinfection / Q000662:veterinary / Q000821:virology; D017931:DNA Primers / Q000235:genetics; D008969:Molecular Sequence Data; D009558:Nipples / Q000821:virology*; D027383:Papillomaviridae / Q000145:classification* / Q000235:genetics; D030361:Papillomavirus Infections / Q000662:veterinary* / Q000821:virology; D010802:Phylogeny; D016133:Polymerase Chain Reaction / Q000662:veterinary; D014860:Warts / Q000662:veterinary / Q000821:virology
chemical_list: D017931:DNA Primers
keywords: cattle; mixed infection; putative new subtype; variant of BPV3