title: [Primary testicular yolk sac tumor: clinicopathological study of 8 cases].
abstract: OBJECTIVE
  To investigate the clinicopathological characteristics, diagnosis and treatment of primary testicular yolk sac tumor (YST).
  
  
  METHODS
  We studied 8 cases of primary testicular YST by microscopy and immunohistochemistry.
  
  
  RESULTS
  The 8 cases of primary testicular YST, including 2 consultation cases, were confirmed from 1998 to 2013, accounting for 10.7% (8/75) of all the testicular germ cell tumors diagnosed in our hospital. The patients ranged in age from 7 to 43 years, 23.9 years on average. The main clinical manifestation of the patients was painless unilateral testis swelling. Microscopically, reticular tissues, schiller-duvaI (S-D) bodies, and eosin-stain transparent bodies were seen in the tumors. One of the cases was confirmed to be simple YST, while the other 7 mixed YST. AFP was a characteristic immunophenotype marker of the tumors.
  
  
  CONCLUSIONS
  Primary testicular YST is a rare malignancyr with poor prognosis. Its diagnosis depends on preoperative AFP test and postoperative pathology. Comprehensive treatment, including orchiectomy, chemotherapy, and radiotherapy, can prolong the survival of the patients.
authors.forename: Fei-Fei
authors.initials: FF
authors.lastname: Liu
authors.forename: Jian-Jun
authors.initials: JJ
authors.lastname: Wang
authors.forename: Qin
authors.initials: Q
authors.lastname: Shen
authors.forename: Bo
authors.initials: B
authors.lastname: Yu
authors.forename: Zhen-Feng
authors.initials: ZF
authors.lastname: Lu
authors.forename: Heng-Hui
authors.initials: HH
authors.lastname: Ma
authors.forename: Qun-Li
authors.initials: QL
authors.lastname: Shi
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D018240:Endodermal Sinus Tumor / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D009919:Orchiectomy; D035583:Rare Diseases / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D013736:Testicular Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D055815:Young Adult