title: Performance of the Verigene Gram-negative blood culture assay for rapid detection of bacteria and resistance determinants.
abstract: Nonduplicate blood cultures that were positive for Gram-negative bacilli (n = 125) were tested by the Verigene Gram-negative blood culture (BC-GN) assay; 117 (90.7%) isolates were members of the panel. For identification and resistance markers, the agreements with routine methods were 97.4% (114/117) and 92.3% (12/13). The BC-GN assay is a rapid and accurate tool for the detection of pathogens from blood cultures and could be integrated alongside conventional systems to enable faster patient management, but the clinical benefits should be further evaluated.
authors.affiliation: Department of Microbiology, Hôpital Erasme, Université Libre de Brussels (ULB), Brussels, Belgium magali.dodemont@erasme.ulb.ac.be.
authors.forename: Magali
authors.initials: M
authors.lastname: Dodémont
authors.affiliation: Department of Microbiology, Hôpital Erasme, Université Libre de Brussels (ULB), Brussels, Belgium.
authors.forename: Ricardo
authors.initials: R
authors.lastname: De Mendonça
authors.affiliation: Department of Microbiology, Hôpital Erasme, Université Libre de Brussels (ULB), Brussels, Belgium.
authors.forename: Claire
authors.initials: C
authors.lastname: Nonhoff
authors.affiliation: Department of Microbiology, Hôpital Erasme, Université Libre de Brussels (ULB), Brussels, Belgium.
authors.forename: Sandrine
authors.initials: S
authors.lastname: Roisin
authors.affiliation: Department of Microbiology, Hôpital Erasme, Université Libre de Brussels (ULB), Brussels, Belgium.
authors.forename: Olivier
authors.initials: O
authors.lastname: Denis
mesh_terms: D001431:Bacteriological Techniques / Q000379:methods*; D001769:Blood / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D006090:Gram-Negative Bacteria / Q000187:drug effects* / Q000302:isolation & purification*; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D013997:Time Factors