title: [Hypofractionated stereotactic radiotherapy of bone metastases].
abstract: Hypofractionated stereotactic radiotherapy can deliver high doses of bone metastases while sparing adjacent healthy tissue not only for a decompressive or analgesic purpose, but also to improve the local control of the irradiated region. Various phases I or II studies showed the feasibility of such an approach at the cost of limited toxicity, including during re-irradiation. Hypofractionated stereotactic radiotherapy to oligometastases may also improve the long-term control of metastatic disease.
authors.affiliation: Service de radiothérapie, institut de cancérologie de l'ouest René-Gauducheau, boulevard Jacques-Monod, 44805 Saint-Herblain, France.
authors.forename: B
authors.initials: B
authors.lastname: Pichon
authors.affiliation: Service de radiothérapie, institut de cancérologie de l'ouest René-Gauducheau, boulevard Jacques-Monod, 44805 Saint-Herblain, France.
authors.forename: F
authors.initials: F
authors.lastname: Thillays
authors.affiliation: Service de radiothérapie, U896, institut régional du cancer de Montpellier, 34298 Montpellier, France.
authors.forename: C
authors.initials: C
authors.lastname: Bourgier
authors.affiliation: Service de radiothérapie, institut de cancérologie de l'ouest René-Gauducheau, boulevard Jacques-Monod, 44805 Saint-Herblain, France.
authors.forename: M-A
authors.initials: MA
authors.lastname: Mahé
authors.affiliation: Service de radiothérapie, institut de cancérologie de l'ouest René-Gauducheau, boulevard Jacques-Monod, 44805 Saint-Herblain, France. Electronic address: stephane.supiot@ico.unicancer.fr.
authors.forename: S
authors.initials: S
authors.lastname: Supiot
mesh_terms: D001859:Bone Neoplasms / Q000473:pathology / Q000556:secondary* / Q000601:surgery*; D003131:Combined Modality Therapy / Q000379:methods; D003245:Consensus Statements as Topic; D003287:Contrast Media; D003952:Diagnostic Imaging; D019583:Dose Fractionation, Radiation; D006801:Humans; D058958:Organs at Risk; D059408:Pain Management; D056888:Patient Positioning; D018579:Patient Selection; D011182:Postoperative Care; D016634:Radiosurgery / Q000009:adverse effects / Q000379:methods*; D061089:Radiotherapy, Image-Guided
chemical_list: D003287:Contrast Media
keywords: Bone metastases; Hypofractionation oligometastases; Hypofractionnement; Métastases osseuses; Oligométastases; Radiotherapy; Radiothérapie; Stereotactic; Stéréotaxie; Vertebrae; Vertèbres