title: Isolated anterior urethral recurrence of prostatic adenocarcinoma.
abstract: Isolated anterior urethral metastases from prostate cancer are rare. The pathogenesis of this form of loco-regional recurrence may be related to spread by instrumentation-induced implantation and could potentially then be associated with a better prognosis than metastatic disease secondary to a more malignant phenotype. We report a case of a 68-year-old man with high-risk prostate cancer, diagnosed at transurethral resection of prostate, who was originally treated with combination external beam radiotherapy and hormonal therapy. He re-presented 4 years after his original diagnosis with recurrent gross hematuria and cystourethroscopic biopsies of anterior urethral polyps revealing isolated recurrent prostatic adenocarcinoma. We present our this case and review the literature.
authors.affiliation: Department of Urology, Queen's University, Kingston General Hospital, Kingston, ON;
authors.forename: Darren
authors.initials: D
authors.lastname: Beiko
authors.affiliation: Division of Radiation Oncology, Queen's University, Kingston General Hospital, Kingston, ON;
authors.forename: Khaled
authors.initials: K
authors.lastname: Zaza
authors.affiliation: Division of Urology, Department of Surgery, Queensway Carleton Hospital, Ottawa, ON.
authors.forename: Kevin V
authors.initials: KV
authors.lastname: Power
authors.affiliation: Department of Urology, Queen's University, Kingston General Hospital, Kingston, ON;
authors.forename: D Robert
authors.initials: DR
authors.lastname: Siemens
authors.affiliation: Department of Pathology, Queen's University, Kingston General Hospital, Kingston, ON;
authors.forename: Alexander H
authors.initials: AH
authors.lastname: Boag