title: AHR: making the keratinocytes thick skinned.
abstract: Dysregulated signals from the external environment and/or the internal milieu of the skin can lead to pathological conditions such as psoriasis. Di Meglio et al. (2014) show that the environment-responsive transcription factor AhR acts in keratinocytes to suppress psoriatic lesions.
authors.affiliation: Washington University School of Medicine, St. Louis, MO, USA. Electronic address: mcolonna@pathology.wustl.edu.
authors.forename: Marco
authors.initials: M
authors.lastname: Colonna
mesh_terms: D000818:Animals; D051792:Basic Helix-Loop-Helix Proteins / Q000276:immunology*; D006801:Humans; D007249:Inflammation / Q000276:immunology*; D011565:Psoriasis / Q000276:immunology*; D018336:Receptors, Aryl Hydrocarbon / Q000276:immunology*
chemical_list: D051792:Basic Helix-Loop-Helix Proteins; D018336:Receptors, Aryl Hydrocarbon; C484722:Ahr protein, mouse