title: Cognitive and behaviour dysfunction of children with neurocysticercosis: a cross-sectional study.
abstract: Eighty-three confirmed cases of neurocysticercosis diagnosed as per modified delBrutto criteria were enrolled in the study (Group-I) to observe cognitive and behavioural changes. Controls consisted of two groups: children with idiopathic generalized tonic-clonic seizure (Group-II) and normal children with non-specific cough (Group-III). Cases and controls were subjected to cognitive and behaviour assessment. There was significant difference in the intelligence quotient (IQ) of cases in domains of visual perception, immediate recall, analysis synthesis and reasoning, verbal ability, memory and spatial ability. In the age group of 6-18 years, cases had significantly more behaviour problems than control without seizure, in domains of anxious depressed, withdrawn depressed, somatic problems, social problems and rule-breaking behaviour. Neurocysticercosis causes decline in cognitive function and behaviours in older children, which should be recognized early for appropriate management and to avoid undue parental anxiety.
authors.affiliation: Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, India rajnitip@gmail.com.
authors.forename: Rajniti
authors.initials: R
authors.lastname: Prasad
authors.affiliation: Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, India.
authors.lastname: Shambhavi
authors.affiliation: Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, India.
authors.forename: Om P
authors.initials: OP
authors.lastname: Mishra
authors.affiliation: Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, India.
authors.forename: Shashi K
authors.initials: SK
authors.lastname: Upadhyay
authors.affiliation: Department of Biostatistics, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, India.
authors.forename: Tej B
authors.initials: TB
authors.lastname: Singh
authors.affiliation: Department of Pediatrics, Nalanda Medical College, Patna 800013, Bihar, India.
authors.forename: Utpal Kant
authors.initials: UK
authors.lastname: Singh
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D003071:Cognition; D003072:Cognition Disorders / Q000175:diagnosis* / Q000469:parasitology / Q000523:psychology; D003430:Cross-Sectional Studies; D004827:Epilepsy / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007360:Intelligence; D007361:Intelligence Tests; D008297:Male; D058069:Neglected Diseases; D020019:Neurocysticercosis / Q000150:complications / Q000175:diagnosis* / Q000523:psychology*; D009483:Neuropsychological Tests; D011239:Prednisolone / Q000627:therapeutic use; D011446:Prospective Studies; D012640:Seizures / Q000150:complications / Q000188:drug therapy; D012920:Social Behavior Disorders / Q000175:diagnosis* / Q000469:parasitology / Q000523:psychology; D016896:Treatment Outcome
chemical_list: D000927:Anticonvulsants; D005938:Glucocorticoids; D011239:Prednisolone
keywords: Neurocysticercosis; behaviour; cognition; computed tomograph; intelligence quotient (IQ)