title: Quinone and hydroquinone metabolites from the ascidians of the genus Aplidium.
abstract: Ascidians of the genus Aplidium are recognized as an important source of chemical diversity and bioactive natural products. Among the compounds produced by this genus are non-nitrogenous metabolites, mainly prenylated quinones and hydroquinones. This review discusses the isolation, structural elucidation, and biological activities of quinones, hydroquinones, rossinones, longithorones, longithorols, floresolides, scabellones, conicaquinones, aplidinones, thiaplidiaquinones, and conithiaquinones. A compilation of the 13C-NMR spectral data of these compounds is also presented.
authors.affiliation: Center for Research in Exact and Technological Sciences, University of Franca, Avenue Doutor Armando Salles Oliveira, 201, Franca, São Paulo 14404-600, Brazil. camila_spereta@hotmail.com.
authors.forename: Camila Spereta
authors.initials: CS
authors.lastname: Bertanha
authors.affiliation: Center for Research in Exact and Technological Sciences, University of Franca, Avenue Doutor Armando Salles Oliveira, 201, Franca, São Paulo 14404-600, Brazil. ana.januario@unifran.edu.br.
authors.forename: Ana Helena
authors.initials: AH
authors.lastname: Januário
authors.affiliation: Center for Research in Exact and Technological Sciences, University of Franca, Avenue Doutor Armando Salles Oliveira, 201, Franca, São Paulo 14404-600, Brazil. farmaciatata@hotmail.com.
authors.forename: Tavane Aparecida
authors.initials: TA
authors.lastname: Alvarenga
authors.affiliation: Center for Research in Exact and Technological Sciences, University of Franca, Avenue Doutor Armando Salles Oliveira, 201, Franca, São Paulo 14404-600, Brazil. leticia_pimenta94@hotmail.com.
authors.forename: Letícia Pereira
authors.initials: LP
authors.lastname: Pimenta
authors.affiliation: Center for Research in Exact and Technological Sciences, University of Franca, Avenue Doutor Armando Salles Oliveira, 201, Franca, São Paulo 14404-600, Brazil. marcio.silva@unifran.edu.br.
authors.forename: Márcio Luis Andrade E
authors.initials: ML
authors.lastname: Silva
authors.affiliation: Center for Research in Exact and Technological Sciences, University of Franca, Avenue Doutor Armando Salles Oliveira, 201, Franca, São Paulo 14404-600, Brazil. wilson.cunha@unifran.edu.br.
authors.forename: Wilson Roberto
authors.initials: WR
authors.lastname: Cunha
authors.affiliation: Center for Research in Exact and Technological Sciences, University of Franca, Avenue Doutor Armando Salles Oliveira, 201, Franca, São Paulo 14404-600, Brazil. patricia.pauletti@unifran.edu.br.
authors.forename: Patrícia Mendonça
authors.initials: PM
authors.lastname: Pauletti
mesh_terms: D000818:Animals; D001688:Biological Products / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D066241:Carbon-13 Magnetic Resonance Spectroscopy; D006801:Humans; D006873:Hydroquinones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D011809:Quinones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014561:Urochordata / Q000378:metabolism*
chemical_list: D001688:Biological Products; D006873:Hydroquinones; D011809:Quinones