title: Managing advanced colorectal cancer: have we reached the PEAK with current therapies?
authors.affiliation: Dana-Farber Cancer Institute; Brigham and Women's Hospital and Harvard Medical School, Boston, MA bwolpin@partners.org.
authors.forename: Brian M
authors.initials: BM
authors.lastname: Wolpin
authors.affiliation: Dana-Farber Cancer Institute; Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
authors.forename: Adam J
authors.initials: AJ
authors.lastname: Bass
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D015179:Colorectal Neoplasms / Q000188:drug therapy*; D005091:Exons / Q000235:genetics*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy*; D008297:Male; D009154:Mutation / Q000235:genetics*; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D016283:Proto-Oncogene Proteins p21(ras); D018631:ras Proteins / Q000235:genetics*
chemical_list: C117307:KRAS protein, human; D011518:Proto-Oncogene Proteins; D016283:Proto-Oncogene Proteins p21(ras); D018631:ras Proteins