title: Imported zika virus infection from the cook islands into australia, 2014.
abstract: A female resident of Townsville, Queensland, Australia has been diagnosed with Zika virus infection following a recent trip to the Cook Islands. An initial serum sample collected in March, 2014 was positive by two separate Zika virus TaqMan real-time RT-PCRs and a pan-Flavivirus RT-PCR. Nucleotide sequencing and phylogenetics of the complete Cook Islands Zika virus envelope gene revealed 99.1% homology with a previous Cambodia 2010 sequence within the Asian lineage. In addition, IgG and IgM antibody seroconversions were detected between paired acute and convalescent phase sera using recombinant Zika virus serology assays. This is the first known imported case of Zika virus infection into northern Queensland where the potential mosquito vector Aedes aegypti is present and only the second such reported case diagnosed within Australia.
authors.affiliation: Forensic and Scientific Services, Coopers Plains, Queensland, Australia.
authors.forename: Alyssa T
authors.initials: AT
authors.lastname: Pyke
authors.affiliation: Tropical Public Health, Townsville, Australia.
authors.forename: Michelle T
authors.initials: MT
authors.lastname: Daly
authors.affiliation: Forensic and Scientific Services, Coopers Plains, Queensland, Australia.
authors.forename: Jane N
authors.initials: JN
authors.lastname: Cameron
authors.affiliation: Forensic and Scientific Services, Coopers Plains, Queensland, Australia.
authors.forename: Peter R
authors.initials: PR
authors.lastname: Moore
authors.affiliation: Forensic and Scientific Services, Coopers Plains, Queensland, Australia.
authors.forename: Carmel T
authors.initials: CT
authors.lastname: Taylor
authors.affiliation: Forensic and Scientific Services, Coopers Plains, Queensland, Australia.
authors.forename: Glen R
authors.initials: GR
authors.lastname: Hewitson
authors.affiliation: Tropical Public Health, Townsville, Australia.
authors.forename: Jan L
authors.initials: JL
authors.lastname: Humphreys
authors.affiliation: Tropical Public Health, Cairns, Australia.
authors.forename: Richard
authors.initials: R
authors.lastname: Gair
keywords: arbovirus; infectious disease