title: Efficient asymmetric synthesis of spiro-2(3H)-furanones via phase-transfer-catalyzed alkynylation.
abstract: Efficient asymmetric synthesis of spiro-2(3H)-furanones was achieved via phase-transfer-catalyzed highly enantioselective alkynylation of cyclic β-keto esters with hypervalent iodine reagents.
authors.affiliation: Laboratory of Synthetic Organic Chemistry and Special Laboratory of Organocatalytic Chemistry, Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto, 606-8502, Japan. maruoka@kuchem.kyoto-u.ac.jp.
authors.forename: Xiangfei
authors.initials: X
authors.lastname: Wu
authors.forename: Seiji
authors.initials: S
authors.lastname: Shirakawa
authors.forename: Keiji
authors.initials: K
authors.lastname: Maruoka
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001688:Biological Products / Q000737:chemistry; D002384:Catalysis; D018360:Crystallography, X-Ray; D003500:Cyclization; D004583:Electrons; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D001688:Biological Products; D013141:Spiro Compounds