title: An expedient approach to pyrrolo[3,2-c]quinolines via regioselective formation of the pyrrole nucleus over indoles.
abstract: An efficient approach for the synthesis of pyrrolo[3,2-c]quinolines (the core nucleus of the natural product martinellic acid) from protected 2-alkynylanilines via the regioselective formation of pyrroles followed by Heck and intramolecular Michael addition has been described.
authors.affiliation: Organometallic Group, Inorganic and Physical Chemistry Division, Indian Institute of Chemical Technology, Hyderabad-500007, India. plikhar@iict.res.in.
authors.forename: Manjusha V
authors.initials: MV
authors.lastname: Karkhelikar
authors.forename: Rajeev R
authors.initials: RR
authors.lastname: Jha
authors.forename: B
authors.initials: B
authors.lastname: Sridhar
authors.forename: Pravin R
authors.initials: PR
authors.lastname: Likhar
authors.forename: Akhilesh K
authors.initials: AK
authors.lastname: Verma
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000814:Aniline Compounds / Q000737:chemistry*; D018360:Crystallography, X-Ray; D003500:Cyclization; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008958:Models, Molecular; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D000814:Aniline Compounds; D011758:Pyrroles; D011804:Quinolines