title: [Application of ozonated perftoran in the treatment of spreaded peritonitis].
abstract: Results of surgical treatment of 114 patients, suffering spreaded peritonitis of various etkoogy, were analyzed. To patients of the comparison group basic conservative therapy was conducted. In patients of the main group was applied intravenous infusion of ozonated perftoran (OP) in 1 mg/kg dose, concentration of ozone 5 mg/l, solely or together with metabolic immunomodulator and detoxicator glutoxim. To all the patients the routine clinical investigations were conducted: in the blood erythrocytes there were measured concentration of diane conjugates, of malonic dialdehyde, activity of catalase, content of the middle molecular mass peptides in blood and urine, as well as of rest nitrogen, urea, creatinine, common bilirubin, state of the protein and electrolyte balance. Basing on analysis of results of the conducted investigations there was revealed, that combined, local and systematic, application of OP and glutoxim together with basic therapy in spreaded peritonitis is pathogenetically substantiated.
authors.forename: I A
authors.initials: IA
authors.lastname: Abdullaev
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005466:Fluorocarbons / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007274:Injections, Intraperitoneal; D007275:Injections, Intravenous; D008875:Middle Aged; D009842:Oligopeptides / Q000008:administration & dosage / Q000627:therapeutic use; D010126:Ozone / Q000008:administration & dosage / Q000627:therapeutic use*; D010538:Peritonitis / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D012720:Severity of Illness Index; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D015415:Biomarkers; D005466:Fluorocarbons; D009842:Oligopeptides; C462699:glutoxim; D010126:Ozone; C063334:perftoran