title: Biochemical effects of glyphosate based herbicide, Excel Mera 71 on enzyme activities of acetylcholinesterase (AChE), lipid peroxidation (LPO), catalase (CAT), glutathione-S-transferase (GST) and protein content on teleostean fishes.
abstract: Effects of glyphosate based herbicide, Excel Mera 71 at a dose of 17.20mg/l on enzyme activities of acetylcholinesterase (AChE), lipid peroxidation (LPO), catalase (CAT), glutathione-S-transferase (GST) and protein content were measured in different tissues of two Indian air-breathing teleosts, Anabas testudineus (Bloch) and Heteropneustes fossilis (Bloch) during an exposure period of 30 days under laboratory condition. AChE activity was significantly increased in all the investigated tissues of both fish species and maximum elevation was observed in brain of H. fossilis, while spinal cord of A. testudineus showed minimum increment. Fishes showed significant increase LPO levels in all the tissues; highest was observed in gill of A. testudineus but lowest LPO level was observed in muscle of H. fossilis. CAT was also enhanced in both the fishes, while GST activity in liver diminished substantially and minimum was observed in liver of A. testudineus. Total protein content showed decreased value in all the tissues, maximum reduction was observed in liver and minimum in brain of A. testudineus and H. fossilis respectively. The results indicated that Excel Mera 71 caused serious alterations in the enzyme activities resulting into severe deterioration of fish health; so, AChE, LPO, CAT and GST can be used as suitable indicators of herbicidal toxicity.
authors.affiliation: Ecotoxicology Lab, Department of Environmental Science, The University of Burdwan, Golapbag, Burdwan 713104, West Bengal, India. Electronic address: samanta.palas2010@gmail.com.
authors.forename: Palas
authors.initials: P
authors.lastname: Samanta
authors.affiliation: Department of Environmental Science, Aghorekamini Prakashchandra Mahavidyalaya, Subhasnagar, Bengai, Hooghly 712611, West Bengal, India. Electronic address: spal.envs@yahoo.co.in.
authors.forename: Sandipan
authors.initials: S
authors.lastname: Pal
authors.affiliation: P.G. Department of Conservation Biology, Durgapur Government College, Durgapur 713214, West Bengal, India. Electronic address: mr.alokemukherjee@gmail.com.
authors.forename: Aloke Kumar
authors.initials: AK
authors.lastname: Mukherjee
authors.affiliation: Ecotoxicology Lab, Department of Environmental Science, The University of Burdwan, Golapbag, Burdwan 713104, West Bengal, India. Electronic address: apurbaghosh2010@gmail.com.
authors.forename: Apurba Ratan
authors.initials: AR
authors.lastname: Ghosh
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism; D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D002374:Catalase / Q000378:metabolism; D002397:Catfishes / Q000378:metabolism*; D029941:Fish Proteins / Q000378:metabolism; D005880:Gills / Q000187:drug effects; D005978:Glutathione / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism; D005998:Glycine / Q000031:analogs & derivatives* / Q000633:toxicity; D006540:Herbicides / Q000633:toxicity*; D007194:India; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000187:drug effects; D009132:Muscles / Q000378:metabolism; D010473:Perciformes / Q000378:metabolism*; D017747:Seafood / Q000032:analysis*; D000097797:Glyphosate
chemical_list: D000110:Acetylcholinesterase; D015415:Biomarkers; D002374:Catalase; D029941:Fish Proteins; D005978:Glutathione; D005982:Glutathione Transferase; D005998:Glycine; D006540:Herbicides; D000097797:Glyphosate
keywords: AChE; CAT; Excel Mera 71; GST; LPO; Teleostean fish