title: Late driveline left ventricular assist device infection treated with frozen-and-thawed allogeneic platelet gel.
abstract: In this case report, we report the application of frozen-and-thawed allogeneic platelet gel (PLT-gel) to treat a late driveline exit site infection in a 56-year old patient supported by a Heartware-HVAD left ventricular assist device. The treatment duration was 4 weeks and at the follow-up the skin around the exit site was free from further infection. PLT-gel can be used to treat local infection of the driveline exit site and to prevent further high-risk infections.
authors.affiliation: Cardiac Surgery Unit, Department of Surgery and Translational Medicine, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy francesco_formica@fastwebnet.it.
authors.forename: Francesco
authors.initials: F
authors.lastname: Formica
authors.affiliation: Transfusion and Immunology Unit, San Gerardo Hospital, Monza, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Perseghin
authors.affiliation: Cardiac Failure Unit, Cardiac-Thoracic-Vascular Department, San Gerardo Hospital, Monza, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Cirò
authors.affiliation: Cardiac Surgery Unit, Department of Surgery and Translational Medicine, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Paolini
mesh_terms: D001684:Biological Dressings; D001792:Blood Platelets; D005615:Freezing; D005782:Gels; D006333:Heart Failure / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D053657:Platelet-Rich Plasma; D011474:Prosthesis Design; D016459:Prosthesis-Related Infections / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy*; D011552:Pseudomonas Infections / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome; D016277:Ventricular Function, Left
chemical_list: D005782:Gels
keywords: Driveline infection; Heartware; Platelet gel