title: [Hepatitis B virus serologic status among hospital health care staff in Lome].
abstract: To assess the hepatitis B virus (HBV) serologic status of hospital health care personnel in Lome. From June 1 to August 31, 2007, 100 workers vaccinated against HBV and 50 unvaccinated workers participated in this comparative cross-sectional study. The data studied were: age, sex, vaccination status, history of accidental exposure to blood, and enzyme-linked immunoassay results for HBs antigen (Ag), total anti-HBc antibodies (Ab), and anti-HBs Ab. Vaccinated subjects had a mean age of 33.2 ± 8.2 years and unvaccinated subjects of 35.2 ± 9.6 years; their respective sex ratios (M:W) were 2:1 and 3:1. Protective levels (>10 IU/L) of anti-HBs Ab were found in 78% (n = 78) of vaccinated subjects compared with 44% (n = 22) of those unvaccinated. HBs Ag was found in 36% (n = 36) of vaccinated and 56% (n = 28) of unvaccinated subjects. Of subjects previously accidentally exposed to blood, 67% (n = 35) had HBs Ag compared with 30% (n = 29) of those subjects without such exposure. This study has proved the high prevalence of HBs Ag carrier status among health care workers in Lome and confirms the importance of vaccination against HBV.
authors.affiliation: Département des sciences fondamentales, faculté des sciences de la santé, université de Lomé, Agoe Logope, 13 BP 378 Lomé, Togo.
authors.forename: A M
authors.initials: AM
authors.lastname: Dorkenoo
authors.affiliation: Département des sciences fondamentales, faculté des sciences de la santé, université de Lomé, Agoe Logope, 13 BP 378 Lomé, Togo.
authors.forename: M
authors.initials: M
authors.lastname: Kolou
authors.affiliation: École supérieure des techniques biologiques et alimentaires de l'université de Lomé, Togo.
authors.forename: H
authors.initials: H
authors.lastname: Sawadogo
authors.affiliation: Centre national de transfusion sanguine de Lomé, Lomé, Togo.
authors.forename: L
authors.initials: L
authors.lastname: Fétéké
authors.affiliation: Département des sciences fondamentales, faculté des sciences de la santé, université de Lomé, Agoe Logope, 13 BP 378 Lomé, Togo.
authors.forename: E
authors.initials: E
authors.lastname: Agbenu
authors.affiliation: Département des sciences fondamentales, faculté des sciences de la santé, université de Lomé, Agoe Logope, 13 BP 378 Lomé, Togo.
authors.forename: S A R
authors.initials: SA
authors.lastname: Issa
authors.affiliation: Département des sciences fondamentales, faculté des sciences de la santé, université de Lomé, Agoe Logope, 13 BP 378 Lomé, Togo.
authors.forename: A Y
authors.initials: AY
authors.lastname: Ségbéna
mesh_terms: D000328:Adult; D002353:Carrier State / Q000175:diagnosis*; D003430:Cross-Sectional Studies; D005260:Female; D006510:Hepatitis B Antibodies / Q000097:blood*; D017325:Hepatitis B Vaccines; D006515:Hepatitis B virus / Q000276:immunology*; D006801:Humans; D008297:Male; D010564:Personnel, Hospital; D014037:Togo; D014611:Vaccination
chemical_list: D006510:Hepatitis B Antibodies; D017325:Hepatitis B Vaccines
keywords: Togo; health-care workers; hepatitis B virus; vaccination