title: Chemical investigation of Cyperus distans L. and inhibitory activity of scabequinone in seed germination and seedling growth bioassays.
abstract: Chemical investigation of the rhizomes of Cyperus distans (Cyperaceae) led to the identification of α-ciperone, cyperotundone and scabequinone, besides other common constituents. Complete assignment of the (13)C NMR data of scabequinone is being published for the first time. The inhibitory effects of C. distans extracts and scabequinone on the seed germination and seedling growth of Mimosa pudica, Senna obtusifolia and Pueraria phaseoloides were evaluated. Seed germination inhibition bioassay revealed that S. obtusifolia (52-53%) was more sensitive to the hexane and the methanol extracts at 1% than M. pudica (0-10%). Scabequinone at 250 mg L⁻¹ displayed seed germination inhibitions more than 50% and radicle growth reduction of more than 35% of the test species S. obtusifolia and P. phaseoloides, while the hypocotyl growth of M. pudica was significantly affected (>50%) by the quinone at the same concentration. These results demonstrate that scabequinone contributes to the overall inhibitory activities of C. distans.
authors.affiliation: a Faculdade de Engenharia Civil, Universidade Federal do Pará , Rua Itaipu n. 36, Tucuruí 68464-00 , Brazil.
authors.forename: Karyme S S
authors.initials: KS
authors.lastname: Vilhena
authors.forename: Giselle Maria Skelding Pinheiro
authors.initials: GM
authors.lastname: Guilhon
authors.forename: Maria das Graças B
authors.initials: Md
authors.lastname: Zoghbi
authors.forename: Lourivaldo Silva
authors.initials: LS
authors.lastname: Santos
authors.forename: Antonio Pedro Silva
authors.initials: AP
authors.lastname: Souza Filho
mesh_terms: D001681:Biological Assay; D001938:Brazil; D029786:Cyperus / Q000737:chemistry*; D018525:Germination / Q000187:drug effects*; D031298:Mimosa / Q000187:drug effects; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D036226:Seedlings / Q000187:drug effects; D012639:Seeds / Q000187:drug effects / Q000254:growth & development; D029846:Senna Plant / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*
chemical_list: D012717:Sesquiterpenes; C000595388:alpha-ciperone; C541832:cyperotundone; C000595389:scabequinone
keywords: 13C NMR; Cyperus distans; phytotoxic activity; scabequinone