title: A case of nonischemic cardiomyopathy associated with autoimmune polyglandular syndrome type III.
abstract: OBJECTIVE
  To report a case of nonischemic dilated cardiomyopathy associated with autoimmune polyglandular syndrome (APS) type III.
  
  
  METHODS
  A review of our patient's medical records was undertaken, and her clinical history, investigations, and outcome are described. In addition, a literature review of nonischemic dilated cardiomyopathy occurring in association with autoimmune polyendocrinopathies was performed.
  
  
  RESULTS
  APS is diagnosed once a patient has developed at least 2 organ specific autoimmune diseases. APS III involves a combination of autoimmune diabetes and Graves' disease without adrenal insufficiency. Autoimmune cardiomyopathies are not described as a feature of this condition; however, there are a few reported cases of patients with autoimmune polyendocrinopathies developing a nonischemic dilated cardiomyopathy. In this case, a 30-year-old female developed vitiligo, Graves' disease, and latent autoimmune diabetes of the adult (LADA) over a 5-year period before presenting with conscious ventricular tachycardia (VT). This evolved into acute severe biventricular failure within a few weeks, which failed to resolve after adequate treatment of her other autoimmune conditions.
  
  
  CONCLUSIONS
  Although nonischemic cardiomyopathies have been associated with APS in a few published cases, this is the first case to our knowledge in a patient with APS III.
authors.affiliation: Department of Endocrinology, Cairns Hospital, Cairns, Australia.
authors.forename: Thomas I
authors.initials: TI
authors.lastname: Hadwen
authors.affiliation: Department of Cardiology, Cairns Hospital, Cairns, Australia.
authors.forename: Katharine
authors.initials: K
authors.lastname: Foster
authors.affiliation: Department of Cardiology, Cairns Hospital, Cairns, Australia.
authors.forename: Jane
authors.initials: J
authors.lastname: Buchanan
authors.affiliation: Department of Cardiology, Cairns Hospital, Cairns, Australia.
authors.forename: Steven
authors.initials: S
authors.lastname: Sutcliffe
authors.affiliation: Department of Endocrinology, Cairns Hospital, Cairns, Australia.
authors.forename: Ashim K
authors.initials: AK
authors.lastname: Sinha