title: Low prevalence of oral and nasal human papillomavirus in employees performing CO2-laser evaporation of genital warts or loop electrode excision procedure of cervical dysplasia.
abstract: Risk of human papillomavirus (HPV) transmission during laser vaporisation of genital warts or loop electrode excision procedure is controversial. An oral rinse, a nasal swabs, history of HPV related diseases and data on HPV exposure were collected from 287 employees at departments of dermato-venerology and gynaecology in Denmark. A mucosal HPV type was found among 5.8% of employees with experience of laser treatment of genital warts as compared to 1.7% of those with no experience (p = 0.12). HPV prevalence was not higher in employees participating in electrosurgical treatment or cryotherapy of genital warts, or loop electrode excision procedure compared with those who did not. HPV 6 or 11 were not detected in any samples. Hand warts after the age of 24 years was more common among dermatology than among non-dermatology personnel (18% vs. 8.0%, p = 0.03). Mucosal HPV types are infrequent in the oral and nasal cavity of health care personnel, however, employees at departments of dermato-venereology are at risk of acquiring hand warts.
authors.affiliation: Department of Dermatovenereology, Copenhagen University Hospital, Bispebjerg, DK-2400 Copenhagen, Denmark. kkofoed@hotmail.com, kristian.kofoed@regionh.dk.
authors.forename: Kristian
authors.initials: K
authors.lastname: Kofoed
authors.forename: Christina
authors.initials: C
authors.lastname: Norrbom
authors.forename: Ola
authors.initials: O
authors.lastname: Forslund
authors.forename: Charlotte
authors.initials: C
authors.lastname: Møller
authors.forename: Ligita P
authors.initials: LP
authors.lastname: Frøding
authors.forename: Anders Elm
authors.initials: AE
authors.lastname: Pedersen
authors.forename: Algirdas
authors.initials: A
authors.lastname: Markauskas
authors.forename: Maria
authors.initials: M
authors.lastname: Blomberg
authors.forename: Jane
authors.initials: J
authors.lastname: Baumgartner-Nielsen
authors.forename: Jakob Torp
authors.initials: JT
authors.lastname: Madsen
authors.forename: Gitte
authors.initials: G
authors.lastname: Strauss
authors.forename: Klaus G
authors.initials: KG
authors.lastname: Madsen
authors.forename: Carsten
authors.initials: C
authors.lastname: Sand
mesh_terms: D003218:Condylomata Acuminata / Q000601:surgery* / Q000821:virology; D003718:Denmark; D004598:Electrosurgery / Q000009:adverse effects; D005260:Female; D061809:Human Papillomavirus DNA Tests; D006801:Humans; D017758:Infectious Disease Transmission, Patient-to-Professional; D053685:Laser Therapy / Q000009:adverse effects / Q000295:instrumentation*; D054020:Lasers, Gas / Q000627:therapeutic use*; D009059:Mouth Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D009061:Mouth Mucosa / Q000821:virology; D009297:Nasal Mucosa / Q000821:virology; D009668:Nose Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D016273:Occupational Exposure; D016272:Occupational Health; D030361:Papillomavirus Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission* / Q000821:virology; D015995:Prevalence; D018570:Risk Assessment; D012307:Risk Factors; D002578:Uterine Cervical Dysplasia / Q000601:surgery* / Q000821:virology