title: Clinical grade purification and expansion of natural killer cells.
abstract: Natural killer (NK) cells have been shown to have important functions in anti-tumor responses and therefore have been used as adoptive immunotherapy for cancer. Here, we review the current methods of ex vivo activation, enrichment, expansion, and shipment of clinical NK cell products.
authors.affiliation: Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX 77030.
authors.forename: Natalia
authors.initials: N
authors.lastname: Lapteva
authors.affiliation: University of Arkansas Medical Center, Little Rock, AK 72205.
authors.forename: Susann M
authors.initials: SM
authors.lastname: Szmania
authors.affiliation: University of Arkansas Medical Center, Little Rock, AK 72205.
authors.forename: Frits
authors.initials: F
authors.lastname: van Rhee
authors.affiliation: Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX 77030.
authors.forename: Cliona M
authors.initials: CM
authors.lastname: Rooney
mesh_terms: D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*; D009369:Neoplasms / Q000276:immunology*