title: Depression in primary care patients with coronary heart disease: baseline findings from the UPBEAT UK study.
abstract: BACKGROUND
  An association between depression and coronary heart disease is now accepted but there has been little primary care research on this topic. The UPBEAT-UK studies are centred on a cohort of primary patients with coronary heart disease assessed every six months for up to four years. The aim of this research was to determine the prevalence and associations of depression in this cohort at baseline.
  
  
  METHODS
  Participants with coronary heart disease were recruited from general practice registers and assessed for cardiac symptoms, depression, quality of life and social problems.
  
  
  RESULTS
  803 people participated. 42% had a documented history of myocardial infarction, 54% a diagnosis of ischaemic heart disease or angina. 44% still experienced chest pain. 7% had an ICD-10 defined depressive disorder. Factors independently associated with this diagnosis were problems living alone (OR 5.49, 95% CI 2.11-13.30), problems carrying out usual activities (OR 3.71, 95% CI 1.93-7.14), experiencing chest pain (OR 3.27, 95% CI 1.58-6.76), other pains or discomfort (OR 3.39, 95% CI 1.42-8.10), younger age (OR 0.95 per year 95% CI 0.92-0.98).
  
  
  CONCLUSIONS
  Problems living alone, chest pain and disability are important predictors of depression in this population.
authors.affiliation: University Department of Mental Health, Dorset HealthCare University NHS Foundation Trust and Bournemouth University, Bournemouth, Dorset, United Kingdom.
authors.forename: Paul
authors.initials: P
authors.lastname: Walters
authors.affiliation: Florence Nightingale School of Nursing and Midwifery, King's College London, London, United Kingdom.
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Barley
authors.affiliation: Section of Primary Care Mental Health, Health Services and Population Research Department, King's College London, London, United Kingdom.
authors.forename: Anthony
authors.initials: A
authors.lastname: Mann
authors.affiliation: Section of Primary Care Mental Health, Health Services and Population Research Department, King's College London, London, United Kingdom.
authors.forename: Rachel
authors.initials: R
authors.lastname: Phillips
authors.affiliation: Section of Primary Care Mental Health, Health Services and Population Research Department, King's College London, London, United Kingdom.
authors.forename: André
authors.initials: A
authors.lastname: Tylee
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003327:Coronary Disease / Q000150:complications* / Q000523:psychology; D003863:Depression / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010045:Outpatients / Q000523:psychology / Q000706:statistics & numerical data; D015995:Prevalence; D011788:Quality of Life; D012923:Social Class