title: Primary angiosarcoma of the breast complicated by the syndrome of disseminated intravascular coagulation (DIC): Case report and literature review.
abstract: Primary angiosarcoma of the breast (PAB) accounts for 0.04% of all breast malignant tumors. It affects young women usually at third or fourth decades of life. PAB clinically manifests as a painless, movable mass with sharp limits. A bluish red discoloration of the overlying skin is often observed. Enlargement of axillary lymph nodes generally does not occur. Angiosarcoma of the breast has a very poor prognosis due to the tendency to metastasize haematogenously and high frequency of local recurrence. Mastectomy and chemotherapy are preferable treatment choices. This paper presents a case of primary angiosarcoma of the breast with a syndrome of disseminated intravascular coagulation (DIC).
authors.affiliation: National Specialized Hospital of Oncology, Sofia, Bulgaria.
authors.forename: Elena
authors.initials: E
authors.lastname: Alexandrova
authors.affiliation: Sofia Cancer Center, Sofia, Bulgaria.
authors.forename: Sonya
authors.initials: S
authors.lastname: Sergieva
authors.affiliation: National Specialized Hospital of Oncology, Sofia, Bulgaria.
authors.forename: Iglika
authors.initials: I
authors.lastname: Mihaylova
authors.affiliation: Specialized Hospital of Haematology, Sofia, Bulgaria.
authors.forename: Antoaneta
authors.initials: A
authors.lastname: Zarkova
keywords: Angiosarcoma; Breast tumors; Disseminated intravascular coagulation