title: A case of reversal of treatment-resistant depression after almost 30 years of symptoms: Case Reports.
abstract: The introduction of antidepressants constituted a breakthrough in the treatment of depression. Despite their success, a significant proportion of patients respond partially or not at all, with detrimental effects for their life. The identification of individual symptom patterns and the employment of new, more specific, drugs targeting the symptoms in question may lead to increased response rates, even in treatment resistant cases. We report a case of long standing depression which responded to reboxetine, a novel noradrenaline re-uptake inhibitor. (Int J Psych Clin Pract 1999; 3: 289-291).
authors.affiliation: Psychopharmacology Unit, School of Medical Sciences, University of Bristol, UK.
authors.forename: S
authors.initials: S
authors.lastname: Argyropoulos
authors.forename: A
authors.initials: A
authors.lastname: Wheeler
authors.forename: D
authors.initials: D
authors.lastname: Nutt
keywords: amotivation; depression; reboxetine; treatment resistant