title: [Motor dysfunction in stroke of subacute stage treated with acupuncture: multi-central randomized controlled study].
abstract: OBJECTIVE
  To verify the clinical efficacy of acupuncture on motor dysfunction in ischemic stroke of subacute stage.
  
  
  METHODS
  The multi-central randomized controlled trial was adopted. One hundred and twenty-six cases of ischemic stroke of subacute stage were randomized into an acupuncture group (61 cases) and a conventional treatment group (65 cases). The basic treatment of western internal medicine and rehabilitation training were applied to the patients of the two groups. In the acupuncture group, acupuncture was supplemented at the body points located on the extensor of the upper limbs and the flexor of the lower limbs. In combination, scalp acupuncture was applied to NS5, MS6 and MS6 on the affected side. The treatment was given 5 times a week and totally 8 weeks were required. The follow-up observation lasted for 3 months. The scores in Fugl-Meyer scale and NIHSS scale and Barthel index were compared between the two groups before treatment, in 4 and 8 weeks of treatment and the 3-month follow-up observation after treatment separately.
  
  
  RESULTS
  In 4 and 8 weeks of treatment and the follow-up observation, Fugl-Meyer scale score was improved obviously in the patients of the two groups (all P<0. 01). In 8 weeks of treatment and the follow-up observation, Fugl-Meyer scale score in the acupuncture groupwas im proved much apparently as compared with that in the conventional treatment group [68. 0 (43. 0,86. 5) vs 52. 5 (30.3, 77.0), 77.0 (49.5, 89.0) vs 63. 0 (33.0, 84.0), both P<0. 05]. Except that NIHSS scale score was not reduced apparently in 4 weeks of treatment in the conventional treatment group (P>0.05), the results of NIHSS scale at the other time points were all decreased obviously as compared with those before treatment in the patients of the two groups (all P<0. 01). In 8 weeks of treatment and the follow-up observation, the results in the acupuncture group were reduced much apparently as compared with those in the conventional treatment group [5. 0 (3.0,8.0) vs 7. 0 (3.0,13.8), 4. 0 (1.5,7.0) vs 6.0 (2.0,11.7) ,both P<0. 05]. In 8 weeks of treatment and the follow-up observation, Barthel index was improved obviously as compared with that before treatment in the patients of the two groups (all P<0. 05). The improvement in the acupuncture group was much more significant as compared with the conventional treatment group [75. 0 (60. 0,87. 5) vs 65. O (36. 3, 87. 5), P<0. 051.
  
  
  CONCLUSIONS
  Based on the conventional treatment, Acupuncture achieves the satisfactory clinical efficacy on motor dysfunction in ischemic stroke of subacute stage.
authors.forename: Li-Fang
authors.initials: LF
authors.lastname: Chen
authors.forename: Jian-Qiao
authors.initials: JQ
authors.lastname: Fang
authors.forename: Yuan-Yuan
authors.initials: YY
authors.lastname: Wu
authors.forename: Rui-Jie
authors.initials: RJ
authors.lastname: Ma
authors.forename: Shou-Yu
authors.initials: SY
authors.lastname: Xu
authors.forename: Lai-Hua
authors.initials: LH
authors.lastname: Shen
authors.forename: Kai-Tao
authors.initials: KT
authors.lastname: Luo
authors.forename: Feng
authors.initials: F
authors.lastname: Gao
authors.forename: Ye-Hua
authors.initials: YH
authors.lastname: Bao
authors.forename: Ke-Feng
authors.initials: KF
authors.lastname: Ni
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Li
mesh_terms: D015670:Acupuncture Therapy; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D020521:Stroke / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome