title: Maternal mindfulness and anxiety during pregnancy affect infants' neural responses to sounds.
abstract: Maternal anxiety during pregnancy has been consistently shown to negatively affect offspring neurodevelopmental outcomes. However, little is known about the impact of positive maternal traits/states during pregnancy on the offspring. The present study was aimed at investigating the effects of the mother's mindfulness and anxiety during pregnancy on the infant's neurocognitive functioning at 9 months of age. Mothers reported mindfulness using the Freiburg Mindfulness Inventory and anxiety using the Symptom Checklist (SCL-90) at ± 20.7 weeks of gestation. Event-related brain potentials (ERPs) were measured from 79 infants in an auditory oddball paradigm designed to measure auditory attention-a key aspect of early neurocognitive functioning. For the ERP responses elicited by standard sounds, higher maternal mindfulness was associated with lower N250 amplitudes (P < 0.01, η(2) = 0.097), whereas higher maternal anxiety was associated with higher N250 amplitudes (P < 0.05, η(2) = 0.057). Maternal mindfulness was also positively associated with the P150 amplitudes (P < 0.01, η(2) = 0.130). These results suggest that infants prenatally exposed to higher levels of maternal mindfulness devote fewer attentional resources to frequently occurring irrelevant sounds. The results show that positive traits and experiences of the mother during pregnancy may also affect the unborn child. Emphasizing the beneficial effects of a positive psychological state during pregnancy may promote healthy behavior in pregnant women.
authors.affiliation: Department of Psychology, Tilburg University, The Netherlands, Department of Psychiatry, University of North Carolina at Chapel Hill, NC, USA, Institute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, MTA, Budapest, Hungary, Institute of Psychology, University of Szeged, Szeged, Hungary, Department of Psychology, Catholic University of Leuven KU Leuven, Belgium, and Flemish Government, Brussels, Belgium.
authors.forename: Marion I
authors.initials: MI
authors.lastname: van den Heuvel
authors.affiliation: Department of Psychology, Tilburg University, The Netherlands, Department of Psychiatry, University of North Carolina at Chapel Hill, NC, USA, Institute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, MTA, Budapest, Hungary, Institute of Psychology, University of Szeged, Szeged, Hungary, Department of Psychology, Catholic University of Leuven KU Leuven, Belgium, and Flemish Government, Brussels, Belgium Department of Psychology, Tilburg University, The Netherlands, Department of Psychiatry, University of North Carolina at Chapel Hill, NC, USA, Institute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, MTA, Budapest, Hungary, Institute of Psychology, University of Szeged, Szeged, Hungary, Department of Psychology, Catholic University of Leuven KU Leuven, Belgium, and Flemish Government, Brussels, Belgium.
authors.forename: Franc C L
authors.initials: FC
authors.lastname: Donkers
authors.affiliation: Department of Psychology, Tilburg University, The Netherlands, Department of Psychiatry, University of North Carolina at Chapel Hill, NC, USA, Institute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, MTA, Budapest, Hungary, Institute of Psychology, University of Szeged, Szeged, Hungary, Department of Psychology, Catholic University of Leuven KU Leuven, Belgium, and Flemish Government, Brussels, Belgium Department of Psychology, Tilburg University, The Netherlands, Department of Psychiatry, University of North Carolina at Chapel Hill, NC, USA, Institute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, MTA, Budapest, Hungary, Institute of Psychology, University of Szeged, Szeged, Hungary, Department of Psychology, Catholic University of Leuven KU Leuven, Belgium, and Flemish Government, Brussels, Belgium.
authors.forename: István
authors.initials: I
authors.lastname: Winkler
authors.affiliation: Department of Psychology, Tilburg University, The Netherlands, Department of Psychiatry, University of North Carolina at Chapel Hill, NC, USA, Institute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, MTA, Budapest, Hungary, Institute of Psychology, University of Szeged, Szeged, Hungary, Department of Psychology, Catholic University of Leuven KU Leuven, Belgium, and Flemish Government, Brussels, Belgium.
authors.forename: Renée A
authors.initials: RA
authors.lastname: Otte
authors.affiliation: Department of Psychology, Tilburg University, The Netherlands, Department of Psychiatry, University of North Carolina at Chapel Hill, NC, USA, Institute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, MTA, Budapest, Hungary, Institute of Psychology, University of Szeged, Szeged, Hungary, Department of Psychology, Catholic University of Leuven KU Leuven, Belgium, and Flemish Government, Brussels, Belgium Department of Psychology, Tilburg University, The Netherlands, Department of Psychiatry, University of North Carolina at Chapel Hill, NC, USA, Institute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, MTA, Budapest, Hungary, Institute of Psychology, University of Szeged, Szeged, Hungary, Department of Psychology, Catholic University of Leuven KU Leuven, Belgium, and Flemish Government, Brussels, Belgium Department of Psychology, Tilburg University, The Netherlands, Department of Psychiatry, University of North Carolina at Chapel Hill, NC, USA, Institute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, MTA, Budapest, Hungary, Institute of Psychology, University of Szeged, Szeged, Hungary, Department of Psychology, Catholic University of Leuven KU Leuven, Belgium, and Flemish Government, Brussels, Belgium bea.vdnbergh@tilburguniversity.edu.
authors.forename: Bea R H
authors.initials: BR
authors.lastname: Van den Bergh
mesh_terms: D000328:Adult; D001007:Anxiety / Q000523:psychology*; D001288:Attention / Q000502:physiology; D001307:Auditory Perception / Q000502:physiology*; D002657:Child Development / Q000502:physiology; D004569:Electroencephalography; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008425:Maternal Behavior / Q000502:physiology* / Q000523:psychology*; D064866:Mindfulness; D009034:Mother-Child Relations; D011247:Pregnancy / Q000523:psychology; D013315:Stress, Psychological / Q000523:psychology
keywords: anxiety; auditory attention; cognitive development; event-related potential; infant; mindfulness