title: Pathology of indolent B-cell neoplasms other than follicular lymphoma.
abstract: Indolent B-cell lymphomas include follicular lymphoma (FL), chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and marginal zone lymphomas (MZLs). They are a diverse group of disorders with different clinical, morphological, immunophenotypic and genetic features. However, because of several histological similarities, such as in cell size and nodular structure, it may sometimes be difficult to differentiate them and to make a definitive diagnosis. In this review article, we summarize the histopathology of indolent B-cell neoplasms excluding FL and including hairy cell leukemia, and briefly mention recent genetic findings useful for their differential diagnosis. In addition, a provisional subtype of low-grade B-cell lymphoma, "prolymphocytic/paraimmunoblastic lymphoma", is described.
authors.affiliation: Pathology Project for Molecular Targets, The Cancer Institute, Japanese Foundation for Cancer Research.
authors.forename: Seiji
authors.initials: S
authors.lastname: Sakata
authors.forename: Naoko
authors.initials: N
authors.lastname: Tsuyama
authors.forename: Kengo
authors.initials: K
authors.lastname: Takeuchi
mesh_terms: D015415:Biomarkers; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D016130:Immunophenotyping; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology*; D008224:Lymphoma, Follicular / Q000473:pathology; D060787:Neoplasm Grading
chemical_list: D015415:Biomarkers