title: A stay of execution: type I interferons pardon T cells from death by natural killers.
abstract: In this issue of Immunity, Crouse et al., (2014) and Xu et al., (2014), show that by modulating the expression of natural killer (NK) cell receptor ligands, type I interferons protect responding T cells against culling by NK cells.
authors.affiliation: Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
authors.forename: Shannon M
authors.initials: SM
authors.lastname: Kahan
authors.affiliation: Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: azajac@uab.edu.
authors.forename: Allan J
authors.initials: AJ
authors.lastname: Zajac
mesh_terms: D000818:Animals; D000950:Antigens, Ly / Q000276:immunology*; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology*; D003602:Cytotoxicity, Immunologic; D007370:Interferon Type I / Q000276:immunology*; D007694:Killer Cells, Natural / Q000276:immunology*; D008216:Lymphocytic Choriomeningitis / Q000276:immunology*; D055627:Natural Cytotoxicity Triggering Receptor 1 / Q000276:immunology*; D053633:Receptor, Interferon alpha-beta / Q000235:genetics* / Q000276:immunology*
chemical_list: D000950:Antigens, Ly; C508032:Ifnar1 protein, mouse; D007370:Interferon Type I; D055627:Natural Cytotoxicity Triggering Receptor 1; C118384:Ncr1 protein, mouse; D053633:Receptor, Interferon alpha-beta