title: Clozapine-induced myoclonic seizures and valproic acid.
abstract: Within a 3-year period, in 220 patients receiving clozapine, we observed myoclonic seizures in two who had no previous epileptic history. Seizures appeared at the titration phase at relatively low doses, and resolved with the addition of valproic acid, allowing further increases of the clozapine dose to therapeutic levels.
authors.affiliation: Department of Psychiatry, Gazi University Faculty of Medicine, Ankara, Turkey.
authors.forename: E
authors.initials: E
authors.lastname: Taner
authors.forename: B
authors.initials: B
authors.lastname: Coşar
authors.forename: E
authors.initials: E
authors.lastname: Işik
keywords: clozapine; myoclonic seizures; schizophrenia; valproic acid