title: Jarid2 links MicroRNA and chromatin in Th17 cells.
abstract: In this issue of Immunity, Escobar et al. (2014) bring microRNAs and chromatin together by showing how activation-induced miR-155 targets the chromatin protein Jarid2 to regulate proinflammatory cytokine production in T helper 17 cells.
authors.affiliation: Lymphocyte Development Group, MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK. Electronic address: matthias.merkenschlager@csc.mrc.ac.uk.
authors.forename: Matthias
authors.initials: M
authors.lastname: Merkenschlager
mesh_terms: D000818:Animals; D016207:Cytokines / Q000235:genetics*; D005786:Gene Expression Regulation; D006801:Humans; D035683:MicroRNAs / Q000378:metabolism*; D063151:Polycomb Repressive Complex 2 / Q000276:immunology* / Q000378:metabolism; D058504:Th17 Cells / Q000276:immunology*
chemical_list: D016207:Cytokines; C547777:JARID2 protein, human; C093650:Jarid2 protein, mouse; C524942:MIRN155 microRNA, human; D035683:MicroRNAs; C532623:Mirn155 microRNA, mouse; D063151:Polycomb Repressive Complex 2