title: Synthetic glycosylated natural products have satisfactory activities.
abstract: Many natural products contain sugar residues, which are essential components for great medicinal importance. The sugar moieties can improve water-solubility of natural products and decrease their toxicity. At the same time, the glycosidic residues are crucial for the activities of natural products. Much effort has been expended over the past decades in developing novel and efficient methodologies to synthesize the glycosylated natural products. This review highlights recent developments in the synthesis of glycosylated natural products. The structure-activity relationships of some of these glycosylated natural products, together with the structure characteristics of their interaction with the biological targets, are also involved.
authors.forename: Gangliang
authors.initials: G
authors.lastname: Huang
authors.affiliation: College of Chemistry, Chongqing Normal University, Chongqing 401331, China. huangdoctor226@163.com.
authors.forename: Xinya
authors.initials: X
authors.lastname: Mei
mesh_terms: D001688:Biological Products / Q000737:chemistry* / Q000494:pharmacology; D006031:Glycosylation; D013329:Structure-Activity Relationship
chemical_list: D001688:Biological Products