title: [Effect of intravenous dexketoprofen use on postoperative analgesic consumption in patients with lumbar disc surgery].
abstract: OBJECTIVE
  The objective of this study was to evaluate the postoperative analgesic effect of a preemptive, single-dose intravenous dexketoprofen administration in patients undergoing lumbar microdiscectomy.
  
  
  METHODS
  A total of 50 ASA I-II patients candidate to laminectomy were included in this study. They were divided in two groups. Patients in Group A were given 50 mg (2 mL) dexketoprofen and those in Group K 2 mL normal saline intravenously by a blinded anesthesia physician, 10 minutes before the start of intervention. All cases underwent general anesthesia. All patients received postoperative patient-controlled analgesia with tramadol. The VAS scores 1, 4, 8, 16 and 24 hours following the operation, sedation and patient satisfaction scores and tramadol consumption were evaluated.
  
  
  RESULTS
  VAS scores recorded during the first 8 postoperative hours and total tramadol amounts were lower, and the patient satisfaction scores higher, in patients given dexketoprofen than control group. Sedation scores and side effects were similar in both groups.
  
  
  CONCLUSIONS
  Single-dose preemptive intravenous dexketoprofen provides effective analgesia especially in the first 8 postoperative hours, reducing tramadol use.
authors.affiliation: Department of Algology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey. ebruk@omu.edu.tr.
authors.forename: Ebru
authors.initials: E
authors.lastname: Kelsaka
authors.affiliation: Department of Algology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey.
authors.forename: Fuat
authors.initials: F
authors.lastname: Güldoğuş
authors.affiliation: Department of Algology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey.
authors.forename: Erhan
authors.initials: E
authors.lastname: Cetinoğlu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D007405:Intervertebral Disc Displacement / Q000601:surgery*; D007660:Ketoprofen / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D007796:Laminectomy; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D016896:Treatment Outcome; D014325:Tromethamine / Q000008:administration & dosage / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D014325:Tromethamine; D007660:Ketoprofen; C118296:dexketoprofen trometamol