title: Accuracy of MR in growth plate measurement.
abstract: OBJECTIVE
  To analyze the accuracy of growth-plate thickness measurements detected on 1.5-T and 7-T MR images using histology sections as a standard of reference.
  
  
  METHODS
  Four defrosted pig tibiae were 1.5-T MR scanned and one fresh tibia was 7-T MR scanned. The height of the growth plate was measured and compared to histology.
  
  
  RESULTS
  Histology measurements showed a mean growth plate thickness of 467 μm (SD = 82.2). The mean growth plate thickness measured in the 7-T MR images was 465 μm (SD = 62.2) and 1,325 μm (SD = 183.5) on 1.5-T MR measurements. We found a better correspondence between the growth plate thickness measured on the 7-T MR and histology samples compared to 1.5 T.
  
  
  CONCLUSIONS
  The growth plate can be identified and measured with high accuracy using 7-T MR. 1.5-T MR can only describe some morphological characteristics.
authors.affiliation: Orthopaedic Research Laboratory, Aarhus University Hospital NBG, Aarhus University, Noerrebrogade 44 Building 1A, 8000, Aarhus C, Denmark, jmshigue@gmail.com.
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: Shiguetomi-Medina
authors.forename: Ole
authors.initials: O
authors.lastname: Rahbek
authors.forename: Steffen
authors.initials: S
authors.lastname: Ringgaard
authors.forename: Maja Sofie
authors.initials: MS
authors.lastname: Kristiansen
authors.forename: Hans
authors.initials: H
authors.lastname: Stødkilde-Jørgensen
authors.forename: Bjarne
authors.initials: B
authors.lastname: Møller-Madsen
mesh_terms: D000818:Animals; D006132:Growth Plate / Q000033:anatomy & histology*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D066298:In Vitro Techniques; D008279:Magnetic Resonance Imaging / Q000379:methods*; D015588:Observer Variation; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013552:Swine; D013977:Tibia / Q000033:anatomy & histology*