title: Enantioselective ruthenium(II)/Xyl-SunPhos/Daipen-catalyzed hydrogenation of γ-ketoamides.
abstract: A series of γ-hydroxy amides were synthesized with high enantioselectivities (up to 99%) using asymmetric hydrogenation of the corresponding γ-ketoamides in the presence of Ru-Xyl-SunPhos-Daipen catalyst providing key building blocks for a variety of naturally occurring and biologically active compounds.
authors.affiliation: School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, China.
authors.forename: Mengmeng
authors.initials: M
authors.lastname: Zhao
authors.forename: Wanfang
authors.initials: W
authors.lastname: Li
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Li
authors.forename: Kai
authors.initials: K
authors.lastname: Ren
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Tao
authors.forename: Xiaomin
authors.initials: X
authors.lastname: Xie
authors.forename: Tahar
authors.initials: T
authors.lastname: Ayad
authors.forename: Virginie
authors.initials: V
authors.lastname: Ratovelomanana-Vidal
authors.forename: Zhaoguo
authors.initials: Z
authors.lastname: Zhang
mesh_terms: D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D006865:Hydrogenation; D015394:Molecular Structure; D010654:Phenylbutyrates / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000577:Amides; C000593323:N-methoxy-N-methyl-4-oxo-4-phenylbutanamide; D010654:Phenylbutyrates; D012428:Ruthenium