title: Keteniminium ion-initiated cascade cationic polycyclization.
abstract: A novel and efficient keteniminium-initiated cationic polycyclization is reported. This reaction, which only requires triflic acid or bistriflimide as promoters, affords a straightforward entry to polycyclic nitrogen heterocycles possessing up to three contiguous stereocenters and seven fused cycles. These complex, polycyclic molecules can be obtained in a single operation from readily available ynamides which were shown to be remarkable building blocks for multiple, consecutive cationic transformations.
authors.affiliation: Laboratoire de Chimie Organique, Service de Chimie et PhysicoChimie Organiques, Université Libre de Bruxelles (ULB) , Avenue F. D. Roosevelt 50, CP160/06, 1050 Brussels, Belgium.
authors.forename: Cédric
authors.initials: C
authors.lastname: Theunissen
authors.forename: Benoît
authors.initials: B
authors.lastname: Métayer
authors.forename: Nicolas
authors.initials: N
authors.lastname: Henry
authors.forename: Guillaume
authors.initials: G
authors.lastname: Compain
authors.forename: Jérome
authors.initials: J
authors.lastname: Marrot
authors.forename: Agnès
authors.initials: A
authors.lastname: Martin-Mingot
authors.forename: Sébastien
authors.initials: S
authors.lastname: Thibaudeau
authors.forename: Gwilherm
authors.initials: G
authors.lastname: Evano