title: [Connective tissue diseases in hospital practice in Ouagadougou (Burkina Faso)].
abstract: To describe the semiological and immunological features of connective tissue diseases seen at the Yalgado Ouédraogo University Hospital in Ouagadougou. A retrospective study reviewed the records of patients seen in the hospital dermatology and internal medicine departments from January 1, 2004, through December 31, 2009 and diagnosed with systemic lupus erythematosus (SLE), systemic sclerosis (ScS), dermatopolymyositis (DPM), primary Gougerot-Sjögren disease (GS), polymyositis (PM) or indeterminate connective tissue disease (ICTD) meeting the criteria of the American College of Rheumatology. The study included 42 patients, 36 women and 6 men. Their mean age was 41.2 years ±11.97 (range: 15-75). SLE was the diagnosis for 10 patients, ScS for 14, DPM for 7, primary GS for 1, PM for 1, and ICTD for 9. Hematologic (93%), cutaneous (88%), and rheumatologic (81%) abnormalities were the most frequent manifestations. The specific auto-antibodies associated with SLE patients were: anti-native DNA (3/6), anti-Sm (3/6), anti-RNP (3/6), and anti-SSA (4/6); anti-Scl 70 antibodies were present in 5 patients with ScS. Connective tissue diseases seem to be rare in Africa, south of the Sahara. However, the very fragmentary studies and the weak healthcare coverage do not allow any definitive conclusions.
authors.affiliation: Service de médecine interne, centre hospitalier universitaire Yalgado, Ouagadougou, Burkina Faso.
authors.forename: D D
authors.initials: DD
authors.lastname: Ouédraogo
authors.affiliation: Service de dermatologie et vénérologie, centre hospitalier universitaire Yalgado, Ouagadougou, Burkina Faso.
authors.forename: N
authors.initials: N
authors.lastname: Korsaga-Somé
authors.affiliation: Service de médecine interne, centre hospitalier universitaire Yalgado, Ouagadougou, Burkina Faso.
authors.forename: J
authors.initials: J
authors.lastname: Zabsonné Tiendrébéogo
authors.affiliation: Service de médecine interne, centre hospitalier universitaire Yalgado, Ouagadougou, Burkina Faso.
authors.forename: H
authors.initials: H
authors.lastname: Tiéno
authors.affiliation: Service de dermatologie et vénérologie, centre hospitalier universitaire Yalgado, Ouagadougou, Burkina Faso.
authors.forename: H
authors.initials: H
authors.lastname: Kaboré
authors.affiliation: Service de dermatologie et vénérologie, centre hospitalier universitaire Yalgado, Ouagadougou, Burkina Faso.
authors.forename: P
authors.initials: P
authors.lastname: Niamba
authors.affiliation: Service de médecine interne, centre hospitalier universitaire Yalgado, Ouagadougou, Burkina Faso.
authors.forename: J
authors.initials: J
authors.lastname: Drabo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001323:Autoantibodies / Q000097:blood; D002050:Burkina Faso / Q000453:epidemiology; D003240:Connective Tissue Diseases / Q000453:epidemiology* / Q000276:immunology; D005260:Female; D006748:Hospital Departments; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: D001323:Autoantibodies
keywords: Burkina Faso; connective tissue diseases; systemic lupus erythematosus; systemic sclerosis