title: Microwave ablation (MWA) for the treatment of a solitary, chemorefractory testicular cancer liver metastasis.
abstract: We present a case of a patient with stage IIIC metastatic seminoma with a persistent chemorefractory liver lesion. The patient was deemed a poor surgical candidate due to the tumor's aggressive biology with numerous other liver lesions treated with chemotherapy and a relatively high probability for additional recurrences. Further chemotherapy with curative intent was not a feasible option due to the fact that the patient had already received second-line high-dose chemotherapy and four cycles of third-line treatment complicated by renal failure, refractory thrombocytopenia, and debilitating neuropathy. After initial failure of laser, microwave ablation of the chemorefractory liver metastasis resulted in prolonged local tumor control and rendered the patient disease-free for more than 35 months, allowing him to regain an improved quality of life.
authors.affiliation: Department of Radiology, Weill-Cornell Medical College, Interventional Radiology Service, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA, eviolari@live.com.
authors.forename: Elena G
authors.initials: EG
authors.lastname: Violari
authors.forename: Elena N
authors.initials: EN
authors.lastname: Petre
authors.forename: Darren R
authors.initials: DR
authors.lastname: Feldman
authors.forename: Joseph P
authors.initials: JP
authors.lastname: Erinjeri
authors.forename: Karen T
authors.initials: KT
authors.lastname: Brown
authors.forename: Stephen B
authors.initials: SB
authors.lastname: Solomon
authors.forename: Michael I
authors.initials: MI
authors.lastname: D'Angelica
authors.forename: Constantinos T
authors.initials: CT
authors.lastname: Sofocleous
mesh_terms: D017115:Catheter Ablation / Q000379:methods*; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000556:secondary* / Q000628:therapy*; D008297:Male; D008872:Microwaves / Q000627:therapeutic use; D008875:Middle Aged; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D015641:Radiography, Interventional; D018239:Seminoma / Q000473:pathology*; D013736:Testicular Neoplasms / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome