title: A novel balloon colonoscope detects significantly more simulated polyps than a standard colonoscope in a colon model.
abstract: BACKGROUND
  Although standard colonoscopy is considered the optimal test to detect adenomas, it can have a significant adenoma miss rate. A major contributing factor to high miss rates is the inability to visualize adenomas behind haustral folds and at anatomic flexures.
  
  
  OBJECTIVE
  To compare the diagnostic yield of balloon-assisted colonoscopy versus standard colonoscopy in the detection of simulated polyps in a colon model.
  
  
  METHODS
  Prospective, cohort study.
  
  
  METHODS
  International gastroenterology meeting.
  
  
  METHODS
  A colon model composed of elastic material, which mimics the flexible structure of haustral folds, allowing for dynamic responses to balloon inflation, with embedded simulated colon polyps (n = 12 silicone "polyps").
  
  
  METHODS
  Fifty gastroenterologists were recruited to identify simulated colon polyps in a colon model, first using standard colonoscopy immediately followed by balloon-assisted colonoscopy.
  
  
  METHODS
  Detection of simulated polyps.
  
  
  RESULTS
  The median polyp detection rate for all simulated polyps was significantly higher with balloon-assisted as compared with standard colonoscopy (91.7% vs 45.8%, respectively; P < .0001). The significantly higher simulated polyp detection rate with balloon-assisted versus standard colonoscopy was notable both for non-obscured polyps (100.0% vs 75.0%; P < .0001) and obscured polyps (88.0% vs 25.0%; P < .0001).
  
  
  CONCLUSIONS
  Non-randomized design, use of a colon model, and simulated colon polyps.
  
  
  CONCLUSIONS
  As compared with standard colonoscopy, balloon-assisted colonoscopy detected significantly more obscured and non-obscured simulated polyps in a colon model. Clinical studies in human participants are being pursued to further evaluate this new colonoscopic technology.
authors.affiliation: Division of Gastroenterology, New York University Langone Medical Center, New York, New York, USA.
authors.forename: Nazia
authors.initials: N
authors.lastname: Hasan
authors.affiliation: Division of Gastroenterology, New York University Langone Medical Center, New York, New York, USA.
authors.forename: Seth A
authors.initials: SA
authors.lastname: Gross
authors.affiliation: Department of Gastroenterology, Rambam Health Care Campus, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
authors.forename: Ian M
authors.initials: IM
authors.lastname: Gralnek
authors.affiliation: Division of Gastroenterology, New York University Langone Medical Center, New York, New York, USA.
authors.forename: Mark
authors.initials: M
authors.lastname: Pochapin
authors.affiliation: Department of Internal Medicine and Gastroenterology, St. Marienkrankenhaus, Frankfurt, Germany.
authors.forename: Ralf
authors.initials: R
authors.lastname: Kiesslich
authors.affiliation: Institute of Gastroenterology, Tel Aviv Sourasky Medical Center and Tel Aviv University, Tel Aviv, Israel.
authors.forename: Zamir
authors.initials: Z
authors.lastname: Halpern
mesh_terms: D000328:Adult; D001291:Attitude of Health Personnel; D002983:Clinical Competence; D003106:Colon; D003111:Colonic Polyps / Q000175:diagnosis*; D020685:Colonoscopes; D003113:Colonoscopy / Q000295:instrumentation*; D004867:Equipment Design; D005260:Female; D005762:Gastroenterology / Q000295:instrumentation*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008953:Models, Anatomic; D011446:Prospective Studies