title: circlize Implements and enhances circular visualization in R.
abstract: CONCLUSIONS
  Circular layout is an efficient way for the visualization of huge amounts of genomic information. Here we present the circlize package, which provides an implementation of circular layout generation in R as well as an enhancement of available software. The flexibility of this package is based on the usage of low-level graphics functions such that self-defined high-level graphics can be easily implemented by users for specific purposes. Together with the seamless connection between the powerful computational and visual environment in R, circlize gives users more convenience and freedom to design figures for better understanding genomic patterns behind multi-dimensional data.
  
  
  METHODS
  circlize is available at the Comprehensive R Archive Network (CRAN): http://cran.r-project.org/web/packages/circlize/
authors.affiliation: Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg Center for Personalized Oncology (DKFZ-HIPO) and Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant Center, Heidelberg University, 69120 Heidelberg, Germany Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg Center for Personalized Oncology (DKFZ-HIPO) and Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant Center, Heidelberg University, 69120 Heidelberg, Germany.
authors.forename: Zuguang
authors.initials: Z
authors.lastname: Gu
authors.affiliation: Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg Center for Personalized Oncology (DKFZ-HIPO) and Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant Center, Heidelberg University, 69120 Heidelberg, Germany.
authors.forename: Lei
authors.initials: L
authors.lastname: Gu
authors.affiliation: Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg Center for Personalized Oncology (DKFZ-HIPO) and Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant Center, Heidelberg University, 69120 Heidelberg, Germany Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg Center for Personalized Oncology (DKFZ-HIPO) and Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant Center, Heidelberg University, 69120 Heidelberg, Germany Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg Center for Personalized Oncology (DKFZ-HIPO) and Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant Center, Heidelberg University, 69120 Heidelberg, Germany.
authors.forename: Roland
authors.initials: R
authors.lastname: Eils
authors.affiliation: Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg Center for Personalized Oncology (DKFZ-HIPO) and Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant Center, Heidelberg University, 69120 Heidelberg, Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Schlesner
authors.affiliation: Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg Center for Personalized Oncology (DKFZ-HIPO) and Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant Center, Heidelberg University, 69120 Heidelberg, Germany Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg Center for Personalized Oncology (DKFZ-HIPO) and Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant Center, Heidelberg University, 69120 Heidelberg, Germany.
authors.forename: Benedikt
authors.initials: B
authors.lastname: Brors
mesh_terms: D000465:Algorithms; D019295:Computational Biology / Q000379:methods*; D003196:Computer Graphics; D016678:Genome; D023281:Genomics / Q000379:methods*; D020407:Internet; D011381:Programming Languages; D012984:Software