title: Detection and characterization of emerging psychoactive substances by ion mobility spectrometry.
abstract: Rapid detection and identification of novel psychoactive substances (NPS) continues to present significant analytical challenges to forensic and analytical chemists. Ion mobility spectrometry (IMS) has been traditionally considered as the analytical technique of choice to detect illicit drugs in security points in airports, borderlines and customs. Databases of the reduced mobility (K0 ) values of illicit drugs are available in the scientific literature and they should be completed with data of emerging designer drugs. In this paper, we have evaluated the effect of different measurement conditions and determined the K0 values of an important number of NPS including different families; such as phenethylamines, cathinones, synthetic cannabinoids and tryptamines among others to be incorporated to the existing data to provide a rapid detection and identification of this emerging threat.
authors.affiliation: Department of Analytical Chemistry, Research Building, University of Valencia, 50 Dr. Moliner St, E-46100, Burjassot, Valencia, Spain.
authors.forename: Sergio
authors.initials: S
authors.lastname: Armenta
authors.forename: Salvador
authors.initials: S
authors.lastname: Garrigues
authors.forename: Miguel
authors.initials: M
authors.lastname: de la Guardia
authors.forename: Judit
authors.initials: J
authors.lastname: Brassier
authors.forename: Manel
authors.initials: M
authors.lastname: Alcalà
authors.forename: Marcelo
authors.initials: M
authors.lastname: Blanco
authors.forename: Clara
authors.initials: C
authors.lastname: Perez-Alfonso
authors.forename: Nieves
authors.initials: N
authors.lastname: Galipienso
mesh_terms: D002186:Cannabinoids / Q000032:analysis; D002853:Chromatography, Liquid; D008401:Gas Chromatography-Mass Spectrometry; D010627:Phenethylamines / Q000032:analysis; D011619:Psychotropic Drugs / Q000032:analysis*; D013057:Spectrum Analysis; D015813:Substance Abuse Detection; D014363:Tryptamines / Q000032:analysis
chemical_list: D002186:Cannabinoids; D010627:Phenethylamines; D011619:Psychotropic Drugs; D014363:Tryptamines
keywords: Designer drugs; amphetamine derivatives; cathinones; ion mobility spectrometry; synthetic cannabinoids; tryptamines