title: Characteristics of distal radius speed of sound data in Chinese mainland men and women.
abstract: Quantitative ultrasound (QUS) assessment of bone health status, as a reliable method, is rapidly gaining popularity. Speed of sound (SOS) is one parameter of skeletal status provided by QUS assessment. The objective of the present study was first to determine the normative distal radius SOS data on healthy Chinese mainland men and women and second to investigate the effects of sex, age, and body size on this parameter. A study cohort consisting of 19,980 healthy Chinese women and 8722 men aged 20-89 yr participated in this investigation. They answered a detailed questionnaire on their healthy condition, and their anthropometric measurements were taken. Their distal radius SOS values were evaluated using the Sunlight ultrasound systems. The distal radius SOS values exhibited a characteristic rise-then-fall pattern with increasing age in both sexes. The peak SOS value occurred at the age of 40-49 both in males and females. Age-related differences were both pronounced among males and females. Pearson correlation and regression analysis showed that age was a major determinant of SOS in both sexes. In females, SOS values had a much stronger correlation with age than male subjects. Body weight was also correlated with SOS but not as well as age. The SOS values of distal radius at present study may be used as normal reference data for Chinese mainland population and will be useful for comparing the results of individual studies and determining diagnostic criteria of osteoporosis by QUS.
authors.affiliation: Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China; Department of Orthopaedic Surgery, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China.
authors.forename: Ligang
authors.initials: L
authors.lastname: Huang
authors.affiliation: Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China; Department of Orthopaedic Surgery, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China.
authors.forename: Jiafei
authors.initials: J
authors.lastname: Pan
authors.affiliation: Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China; Institute of Orthopaedics and Traumatology of Zhejiang Province, Hangzhou, Zhejiang Province, China.
authors.forename: Hongting
authors.initials: H
authors.lastname: Jin
authors.affiliation: Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China; Department of Orthopaedic Surgery, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China; Institute of Orthopaedics and Traumatology of Zhejiang Province, Hangzhou, Zhejiang Province, China.
authors.forename: Luwei
authors.initials: L
authors.lastname: Xiao
authors.affiliation: Hangzhou Women's Federation, Hangzhou, Zhejiang Province, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Tao
authors.affiliation: Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China; Department of Orthopaedic Surgery, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China; Institute of Orthopaedics and Traumatology of Zhejiang Province, Hangzhou, Zhejiang Province, China. Electronic address: tongpeijian@yeah.net.
authors.forename: Peijian
authors.initials: P
authors.lastname: Tong
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D015519:Bone Density; D002681:China; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011884:Radius / Q000000981:diagnostic imaging*; D012016:Reference Values; D012737:Sex Factors; D014463:Ultrasonography; D055815:Young Adult
keywords: Age; distal radius; osteoporosis; quantitative ultrasound; speed of sound