title: [Influence of the comorbidity diseases and risk factors on development of the combined peptic ulcer of the stomach and the duodenum].
abstract: OBJECTIVE
  To define influence of the comorbidity diseases and risk factors of development of the combined peptic ulcer of a stomach and duodenum.
  
  
  METHODS
  As a result of carried-out poll and inspection 250 patients with an exacerbation of a peptic ulcer were surveyed. Patients were distributed in 3 groups of observation depending on localization of ulcerative process. At all surveyed questioning was carried out, data on hereditary load, smoking, alcohol intake, existence of somatopathies were specified, clinic-morphological implications of a peptic ulcer were studied.
  
  
  RESULTS
  The peptic ulcer of a stomach is characteristic for women (72.1%) and develops mainly aged from 45 till 59 years (60.3%). Peptic ulcer of duodenum men (76.3%) suffer mainly, the debut is the share in most cases of age from 18 to 44 years (79.1%). The combined canker of a stomach and duodenum meets at males (61.2%) more often, is initially involved in process ulcerogenesis by duodenum generally aged from 30 till 44 years (64.2%), accession of a canker of a stomach happens is delayed (at 38.8% within 16 and more years). In the analysis of risk factors at patients with the combined peptic ulcer of a stomach and duodenum depending on existence or absence specific to this category of patients of a background from such comorbidity diseases as IBS, HOBL and widespread osteochondrosis taped that larger prevalence of smoking (100%) and as the use (50%) and the excessive use (50%), alcohol are characteristic for the patients having a high comorbidity (a combination of three above nosologies).
  
  
  CONCLUSIONS
  The greatest interest in respect of possible communication with formation of the combined peptic ulcer of a stomach and duodenum is represented by IBS, HOBL and osteochondrosis. And major factors of risk were smoking, the excessive alcohol intake, the burdened heredity.
authors.forename: L A
authors.initials: LA
authors.lastname: Stepanishcheva
authors.forename: A S
authors.initials: AS
authors.lastname: Sarsenbaeva
authors.forename: N V
authors.initials: NV
authors.lastname: Fattakhova
mesh_terms: D000328:Adult; D000367:Age Factors; D004381:Duodenal Ulcer / Q000453:epidemiology* / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D004386:Duodenum / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012737:Sex Factors; D013270:Stomach / Q000473:pathology / Q000503:physiopathology; D013276:Stomach Ulcer / Q000453:epidemiology* / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology