title: [Case of ataxic sensory neuronopathy associated with Sjögren's syndrome].
abstract: A 71-year-old woman developed advanced thermal hypoalgesia, bathyesthesia, and significant sensory ataxia 1 year ago. She also had difficulty maintaining a sitting posture. Patchy and reduced thermal nociception corresponding to a dermatome was found in her four extremities and trunk. On the basis of several tests, she was diagnosed with ataxic sensory neuronopathy due to dorsal root ganglionitis associated with Sjögren's syndrome. Generally, dorsal root ganglionitis associated with Sjögren's syndrome is refractory. After treatment with simple plasmapheresis, she was able to maintain a sitting posture. Finally, her symptoms stabilized after the inclusion of oral D-penicillamine to her treatment regimen. Although the clinical course was observed for about one year, we report this case because of its valuable finding, i.e., her symptoms improved after simple plasmapheresis and oral administration of D-penicillamine.
authors.affiliation: Department of Neurology, Shizuoka General Hospital.
authors.forename: Masanori
authors.initials: M
authors.lastname: Sawamura
authors.forename: Wataru
authors.initials: W
authors.lastname: Oishi
authors.forename: Etsuro
authors.initials: E
authors.lastname: Nakanishi
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Maruhama
authors.forename: Gan
authors.initials: G
authors.lastname: Kim
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Harada
mesh_terms: D000368:Aged; D001259:Ataxia / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D005260:Female; D005727:Ganglia, Spinal; D006801:Humans; D009443:Neuritis / Q000150:complications* / Q000628:therapy; D015401:Nursing Administration Research; D010396:Penicillamine / Q000008:administration & dosage; D010956:Plasmapheresis; D011187:Posture; D012859:Sjogren's Syndrome / Q000150:complications* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D010396:Penicillamine