title: Advantages of laparoscopic abdominoperineal resection for anastomotic recurrence of rectal cancer.
abstract: BACKGROUND
  Surgery offers the only potential for cure and long-term survival of recurrence of rectal cancer. Few studies about laparoscopic recurrent lesion resection have been reported. This study was designed to evaluate the safety and feasibility of laparoscopic abdomino-perineal resection for anastomotic recurrence of rectal cancer.
  
  
  METHODS
  Data for 42 patients with recurrence of rectal cancer were collected retrospectively. Of the 42 patients, 22 underwent laparoscopic surgery (LR group) and 20 received open surgery (OR group). Outcomes between the two groups were compared.
  
  
  RESULTS
  Operation time in LR group was shorter compared with the OR group (164.6 ± 27.7 min vs 203.0 ± 45.3 min); intra-operative blood loss was 119.7 ± 44.4 ml and 185.0 ± 94.0 ml in LR group and OR group, respectively (p<0.001); time to first flatus in LR group was shorter than in OR group, and the difference was statistically significant (2.6 ± 0.8 days vs 3.1 ± 0.8 days, p=0.013); hospital stay in the LR and OR groups was 8.6 ± 1.3 days and 9.8 ± 2.2 days; 3-year survival rates in the LR and OR groups were 44.4% and 42.8% (p=0.915) and the 3-year disease-free survival rates were 36.4% and 30.0%, respectively (p=0.737).
  
  
  CONCLUSIONS
  Laparoscopic abdomino-perineal resection is safe and feasible for anastomotic recurrence of rectal cancer.
authors.affiliation: Department of Gastrointestinal Surgery, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China E-mail : zhouzx_01@163.com.
authors.forename: Xing-Mao
authors.initials: XM
authors.lastname: Zhang
authors.forename: Zheng
authors.initials: Z
authors.lastname: Wang
authors.forename: Sheng-Hui
authors.initials: SH
authors.lastname: Ma
authors.forename: Zhi-Xiang
authors.initials: ZX
authors.lastname: Zhou
mesh_terms: D000005:Abdomen; D016063:Blood Loss, Surgical; D013505:Digestive System Surgical Procedures / Q000401:mortality*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D010502:Perineum / Q000473:pathology / Q000601:surgery*; D012004:Rectal Neoplasms / Q000401:mortality / Q000601:surgery*; D012007:Rectum / Q000473:pathology / Q000601:surgery; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome