title: Evaluation of patients with diffuse unilateral subacute neuroretinitis by spectral domain optical coherence tomography with enhanced depth imaging.
abstract: BACKGROUND
  The purpose of this study was to determine the value of spectral domain optical coherence tomography (SD-OCT) in assessing patients with diffuse unilateral subacute neuroretinitis (DUSN).
  
  
  METHODS
  This was an observational case series with clinical imaging correlation performed at the Retina and Vitreous Institute of Londrina and State University of Londrina, Paraná, Brazil. The series comprised ten consecutive patients with a confirmed diagnosis of DUSN, ie, seven patients with late-stage disease and three with early-stage disease, who were assessed by SD-OCT for mean macular, retinal nerve fiber layer, and choroidal thickness using enhanced depth imaging software.
  
  
  RESULTS
  Comparing the affected eye with the healthy fellow eye, significant diffuse atrophy of the retinal layers with a decrease in mean macular (P=0.004) and retinal nerve fiber layer (P=0.002) thickness was found in all cases. There was no difference in choroidal thickness (P=0.262).
  
  
  CONCLUSIONS
  The correlation of SD-OCT results with central vision and funduscopic findings may explain the profound loss of visual function in patients with DUSN.
authors.affiliation: State University of Londrina, Londrina, Brazil.
authors.forename: Rodrigo F
authors.initials: RF
authors.lastname: Berbel
authors.affiliation: State University of Londrina, Londrina, Brazil.
authors.forename: Antonio Marcelo B
authors.initials: AM
authors.lastname: Casella
authors.affiliation: Federal University of São Paulo, São Paulo, Federative Republic of Brazil, Brazil.
authors.forename: Eduardo C
authors.initials: EC
authors.lastname: de Souza
authors.affiliation: Federal University of São Paulo, São Paulo, Federative Republic of Brazil, Brazil.
authors.forename: Michel E
authors.initials: ME
authors.lastname: Farah
keywords: diffuse unilateral subacute neuroretinitis; enhanced depth imaging; eye infections; optical coherence tomography; parasitic; retinitis