title: Relationships of Circadian Rhythms and Physical Activity With Objective Sleep Parameters in Lung Cancer Patients.
abstract: BACKGROUND
  Lung cancer patients undergo various treatments leading to sleep problems, rest-activity circadian rhythms disruption, and reduced levels of physical activity. It is important to understand the relationships among these variables. Appropriate interventions can possibly be implemented to improve sleep quality in lung cancer patients.
  
  
  OBJECTIVE
  The objective of this study was to examine the relationships of circadian rhythms and physical activity with objective sleep parameters in 106 of Taiwanese lung cancer patients.
  
  
  METHODS
  This study used a cross-sectional design. The instruments included an actigraph to measure the objective sleep parameters (total sleep time [TST], sleep efficiency, and sleep-onset latency [SOL]), rest-activity circadian rhythms (r24 [24-hour autocorrelation coefficient] and I < O [in-bed less than out-of-bed dichotomy index]), and physical activity frequency (UP activity mean). The daily physical activity amount in minutes was measured by the Bouchard 3-day physical activity record.
  
  
  RESULTS
  Patients performing light-intensity physical activity of 295 min/d or greater had better values for the TST, sleep efficiency, SOL, r24, and I < O than those performing less than 295 min/d (all P < .05). Significant predictors of the TST included age (β = -.31), I < O (β = .32), and UP activity mean (β = -.42). Predictors of the SOL included current treatment (β = .20), I < O (β = -.28), UP activity mean (β = .51), and 24-hour light-activity minutes (β = -.23).
  
  
  CONCLUSIONS
  Marked circadian rhythms and adequate light-intensity physical activity may improve sleep quality in lung cancer patients.
  
  
  CONCLUSIONS
  Adequate light-intensity physical activity can be an effective intervention to improve sleep quality in lung cancer patients.
authors.affiliation: Author Affiliations: Graduate Institute of Nursing (Ms Chen) and School of Nursing (Dr Lin), College of Nursing, Taipei Medical University (Dr Tzeng); School of Nursing, College of Nursing, National Taipei University of Nursing and Health Sciences (Ms Chen); Division of Thoracic Surgery, Department of Surgery (Dr Wu) and Chest Department (Dr Tasi), Veterans General Hospital-Taipei; and School of Medicine, National Yang-Ming University, Taipei, Taiwan (Drs Wu and Tasi); Department of Anesthesiology, Chi-Mei Medical Center, Yong Kang; and Department of Food Sciences and Technology, Chia Nan University of Pharmacy and Science, Jen-Te, Tainan City, Taiwan (Dr Tzeng).
authors.forename: Hui-Mei
authors.initials: HM
authors.lastname: Chen
authors.forename: Yu-Chung
authors.initials: YC
authors.lastname: Wu
authors.forename: Chun-Ming
authors.initials: CM
authors.lastname: Tsai
authors.forename: Jann-Inn
authors.initials: JI
authors.lastname: Tzeng
authors.forename: Chia-Chin
authors.initials: CC
authors.lastname: Lin
mesh_terms: D056044:Actigraphy / Q000379:methods; D000367:Age Factors; D000368:Aged; D000554:Ambulatory Care Facilities; D002940:Circadian Rhythm; D015897:Comorbidity; D003430:Cross-Sectional Studies; D015444:Exercise / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000175:diagnosis / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012307:Risk Factors; D012737:Sex Factors; D012893:Sleep Wake Disorders / Q000175:diagnosis* / Q000453:epidemiology*; D013624:Taiwan; D014505:Urban Population