title: Detection of glutamate and acetylcholine with organic electrochemical transistors based on conducting polymer/platinum nanoparticle composites.
abstract: The aim of the study is to open a new scope for organic electrochemical transistors based on PEDOT:PSS, a material blend known for its stability and reliability. These devices can leverage molecular electrocatalysis by incorporating small amounts of nano-catalyst during the transistor manufacturing (spin coating). This methodology is very simple to implement using the know-how of nanochemistry and results in efficient enzymatic activity transduction, in this case utilizing choline oxidase and glutamate oxidase.
authors.affiliation: Linköping University, ITN, Laboratory of Organic Electronics, SE-601 74, Sweden.
authors.forename: Loïg
authors.initials: L
authors.lastname: Kergoat
authors.forename: Benoît
authors.initials: B
authors.lastname: Piro
authors.forename: Daniel T
authors.initials: DT
authors.lastname: Simon
authors.forename: Minh-Chau
authors.initials: MC
authors.lastname: Pham
authors.forename: Vincent
authors.initials: V
authors.lastname: Noël
authors.forename: Magnus
authors.initials: M
authors.lastname: Berggren
mesh_terms: D000109:Acetylcholine / Q000032:analysis; D000429:Alcohol Oxidoreductases / Q000737:chemistry; D002384:Catalysis; D055664:Electrochemical Techniques / Q000295:instrumentation* / Q000379:methods*; D018698:Glutamic Acid / Q000032:analysis; D006861:Hydrogen Peroxide / Q000737:chemistry; D053768:Metal Nanoparticles / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D017671:Platinum Compounds / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D012680:Sensitivity and Specificity; D014173:Transistors, Electronic
chemical_list: D017671:Platinum Compounds; D011108:Polymers; D018698:Glutamic Acid; D006861:Hydrogen Peroxide; D000429:Alcohol Oxidoreductases; C019888:choline oxidase; D000109:Acetylcholine
keywords: PEDOT:PSS; bioelectronics; electrochemical transistors; neurotransmitters; platinum nanoparticles