title: [How I explore and treat a neonatal renal vein thrombosis: a case report].
abstract: Neonatal renal vein thrombosis is a rare condition. The present case is rather unfrequent and particularly educative since it shows the complete diagnostic triad including hematuria, flank mass and thrombocytopenia. The diagnosis relies on the demonstration, by Doppler ultrasound, of an obstructed renal venous bed. The investigation is completed by a platelet count and the determination of the prothrombin time, of the activated partial thromboplastin time as well as of the concentration of fibrinogen. The screening also includes the search for a possible etiology, such as a deficiency in coagulation proteins, the presence of antiphospholipid antibodies or of a genetic mutation of one of the coagulation factors. Since there exist no evidence based guidelines for the management of the disease, we will discuss the diagnosis and treatment in relation with the published literature.
authors.forename: S
authors.initials: S
authors.lastname: Tribolet
authors.forename: M F
authors.initials: MF
authors.lastname: Dresse
authors.forename: J
authors.initials: J
authors.lastname: Lombet
authors.forename: V
authors.initials: V
authors.lastname: Rigo
authors.forename: C
authors.initials: C
authors.lastname: Pieltain
authors.forename: M
authors.initials: M
authors.lastname: Kalenga
mesh_terms: D000328:Adult; D005340:Fibrinogen / Q000378:metabolism; D006417:Hematuria / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008297:Male; D010314:Partial Thromboplastin Time; D010976:Platelet Count; D011517:Prothrombin Time; D012082:Renal Veins / Q000000981:diagnostic imaging / Q000473:pathology*; D013921:Thrombocytopenia / Q000175:diagnosis / Q000209:etiology; D018608:Ultrasonography, Doppler / Q000379:methods; D020246:Venous Thrombosis / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*
chemical_list: D005340:Fibrinogen