title: [Pheochromocytoma in pregnancy].
abstract: Pheochromocytoma occurs with a frequency estimated at 2-7 per 100,000 pregnant women. Unrecognized, and thus untreated pheochromocytoma is associated with very high (40-50%) maternal and fetal mortality. Pheochromocytoma occurs sporadically or as a family trait. Its presence should be suspected in women with paroxysmal or established hypertension, especially before the 20th week of pregnancy, accompanied by headaches and palpitations, and excessive sweating, muscle tremors, vomiting, anxiety, vasomotor disturbances and blurred vision. The variety of clinical presentations and rarity are the cause of not including the disease in differential diagnosis of hypertension in pregnancy. Biochemical tests are essential in the diagnosis of pheochromocytoma, and involving the assessment of methoxycatecholamine urinary excretion. The second step in the diagnostics is magnetic resonance imaging of adrenal glands. Adrenalectomy is the treatment of choice for pheochromocytoma with adrenal location, which depends on the timing of the tumor diagnosis. Conservative treatment for 10-14 days with pharmacological blockade of alpha-adrenergic receptors should precede the surgery. Early diagnosis and properly planned treatment of pheochromocytoma significantly reduces the risk to the mother and fetus.
authors.affiliation: Zakład Patofizjologii Katedry Patofizjologii Wydziału Lekarskiego Śląskiego Uniwersytetu Medycznego w Katowicach.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Wyskida
authors.affiliation: Zakład Promocji Zdrowia i Leczenia Otyłości Katedry Patofizjologii Wydziału Lekarskiego Śląskiego Uniwersytetu Medycznego w Katowicach.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Wyskida
authors.affiliation: Klinika Intensywnej Terapii i Patologii Noworodka Katedry Pediatrii Wydziału Lekarskiego Śląskiego Uniwersytetu Medycznego w Katowicach.
authors.forename: Iwona
authors.initials: I
authors.lastname: Maruniak-Chudek
authors.affiliation: Katedra i Klinika Perinatologii Wydziału Nauk o Zdrowiu Śląskiego Uniwersytetu Medycznego w Katowicach.
authors.forename: Jerzy
authors.initials: J
authors.lastname: Sikora
authors.affiliation: Zakład Patofizjologii Katedry Patofizjologii Wydziału Lekarskiego Śląskiego Uniwersytetu Medycznego w Katowicach.
authors.forename: Jerzy
authors.initials: J
authors.lastname: Chudek
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D000315:Adrenalectomy; D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D010673:Pheochromocytoma / Q000175:diagnosis* / Q000628:therapy*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis* / Q000628:therapy*
chemical_list: D000317:Adrenergic alpha-Antagonists