title: Efficacy of hemocontrol biofeedback system in intradialytic hypotension-prone hemodialysis patients.
abstract: We conducted a study to determine whether the hemocontrol biofeedback system (HBS) can improve intradialytic hypotension (IDH) in hypotension-prone hemodialysis (HD) patients compared with conventional HD. In this multicenter prospective crossover study, 60 hypotension-prone patients were serially treated by conventional HD for 8 weeks (period A), by HD with hemoscan blood volume monitoring for 2 weeks (period B0), and by HBS HD for 8 weeks (period B1). The number of sessions complicated by symptomatic IDH during 24 HD sessions (14.9 ± 5.8 sessions, 62.1% in period A vs 9.2 ± 7.2 sessions, 38.4% in period B1, P<0.001) and the number of IDH-related nursing interventions in a session (0.96 ± 0.66 in period A vs 0.56 ± 0.54 in period B1, P<0.001) significantly decreased in period B1 than in period A. Recovery time from fatigue after dialysis was significantly shorter in period B1 than in period A. The patients with higher post-dialysis blood pressure, lower difference between pre- and post-dialysis blood pressure, less frequent IDH, and higher pre- and post-dialysis body weight in period A responded better to HBS in period B1 in regard to the reduction of IDH. In conclusion, HBS may improve the patient tolerability to HD by reducing the IDH frequency and promoting faster recovery from fatigue after dialysis.
authors.affiliation: Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.
authors.forename: Hyo-Wook
authors.identifier: 0000-0003-2550-2739
authors.initials: HW
authors.lastname: Gil
authors.affiliation: Department of Internal Medicine, Eulji University School of Medicine, Daejeon, Korea.
authors.forename: Kitae
authors.initials: K
authors.lastname: Bang
authors.affiliation: Department of Internal Medicine, Eulji University School of Medicine, Seoul, Korea.
authors.forename: So Young
authors.initials: SY
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
authors.forename: Byoung Geun
authors.initials: BG
authors.lastname: Han
authors.affiliation: Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.
authors.forename: Jin Kuk
authors.initials: JK
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, The Catholic University of Korea, Uijeongbu St. Mary's Hospital, Uijeongbu, Korea.
authors.forename: Young Ok
authors.initials: YO
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, The Catholic University of Korea, Bucheon St. Mary's Hospital, Bucheon, Korea.
authors.forename: Ho Cheol
authors.initials: HC
authors.lastname: Song
authors.affiliation: Department of Internal Medicine, Korea University Guro Hospital, Seoul, Korea.
authors.forename: Young Joo
authors.initials: YJ
authors.lastname: Kwon
authors.affiliation: Department of Internal Medicine, The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, Korea.
authors.forename: Yong-Soo
authors.identifier: 0000-0003-2152-1289
authors.initials: YS
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001676:Biofeedback, Psychology; D001794:Blood Pressure; D001810:Blood Volume; D001835:Body Weight; D018592:Cross-Over Studies; D005221:Fatigue; D005260:Female; D006801:Humans; D007022:Hypotension / Q000209:etiology / Q000517:prevention & control*; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D016684:Prone Position; D011446:Prospective Studies; D006435:Renal Dialysis / Q000009:adverse effects; D055815:Young Adult
keywords: Clinical Trial; Dialysis Volume; Hypotension; Renal Dialysis