title: Selective Kumada biaryl cross-coupling reaction enabled by an iron(III) alkoxide-N-heterocyclic carbene catalyst system.
abstract: A catalyst system comprising Fe2(O(t)Bu)6 and an N-heterocyclic carbene ligand enables efficient syntheses of (hetero)biaryls from the reactions of aryl Grignard reagents with a diverse spectrum of (hetero)aryl chlorides. Amongst the alkoxide and amide counterions investigated, tert-butoxide was the most effective in inhibiting the homocoupling of arylmagnesiums.
authors.affiliation: Institute of Chemical and Engineering Sciences (ICES), Agency for Science, Technology and Research (A*STAR), 8, Biomedical Grove, Neuros, #07-01, Singapore 138665. duong_hung@ices.a-star.edu.sg.
authors.forename: Yi-Yuan
authors.initials: YY
authors.lastname: Chua
authors.forename: Hung A
authors.initials: HA
authors.lastname: Duong
mesh_terms: D000577:Amides / Q000737:chemistry; D002384:Catalysis; D056831:Coordination Complexes / Q000737:chemistry; D005290:Ferric Compounds / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D010087:Oxides / Q000737:chemistry
chemical_list: D000577:Amides; D056831:Coordination Complexes; D005290:Ferric Compounds; D006571:Heterocyclic Compounds; D010087:Oxides; C030011:carbene; D008697:Methane