title: [Diagnostic value of autoantibodies to asialoglycoprotein receptor in autoimmune hepatitis].
abstract: Among 106 patients with autoimmune liver disease in 12 (11.3%) were found autoantibodies to asialoglycoprotein receptor (anti-ASGPR): in 5 (9.1%) of 55 with PBC, and 4 (17.4%) of 23 with AIH and 3 (10.7%) of 28 patients with syndrome chiasm (PBC + AIH). Detection of antibodies against the ASGPR is an effective method for diagnosis of autoimmune hepatitis. Further improvement of this method allows for monitoring and disease. Anti-ASGPR levels correlate with biochemical parameters and with the severity and manifestation autoimmune processes in patients with autoimmune hepatitis.
authors.forename: V É
authors.initials: VÉ
authors.lastname: Sagynbaeva
authors.forename: L B
authors.initials: LB
authors.lastname: Lazebnik
authors.forename: E V
authors.initials: EV
authors.lastname: Vinnitskaia
authors.forename: A S
authors.initials: AS
authors.lastname: Dorofeev
authors.forename: L I
authors.initials: LI
authors.lastname: Efremov
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D037263:Asialoglycoprotein Receptor / Q000276:immunology*; D001323:Autoantibodies / Q000097:blood / Q000276:immunology; D005260:Female; D019693:Hepatitis, Autoimmune / Q000097:blood / Q000175:diagnosis / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D037263:Asialoglycoprotein Receptor; D001323:Autoantibodies