title: Significance of 18 F-FDG PET and immunohistochemical GLUT-1 expression for cardiac myxoma.
abstract: Cardiac tumours are relatively rare and are difficult to diagnose merely with imaging techniques. We demonstrated an unusual case of left atrial myxoma, displaying the successful detection by positron emission tomography using 2-deoxy-2-[18 F] fluoro-D-glucose (18 F-FDG PET), correlated closely to more intense and enhanced immunoreactivity with glucose transporter-1 (GLUT-1) in a substantial number of cardiac myxoma cells. Further prospective studies are needed to validate the significance of 18 F-FDG PET findings for cardiac myxoma and the association with immunohistochemical GLUT-1 expression in its tumour cells, after collecting and investigating a larger number of surgical cases examined with both of them.
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authors.forename: Yukio
authors.initials: Y
authors.lastname: Okazaki
authors.affiliation: Department of Pathology and Cell Biology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan. sousuke@med.uoeh-u.ac.jp.
authors.forename: Sohsuke
authors.initials: S
authors.lastname: Yamada
authors.forename: Shohei
authors.initials: S
authors.lastname: Kitada
authors.forename: Iwao
authors.initials: I
authors.lastname: Matsunaga
authors.forename: Eijirou
authors.initials: E
authors.lastname: Nogami
authors.forename: Teruo
authors.initials: T
authors.lastname: Watanabe
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Sasaguri
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Honma
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Itou
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis*; D001706:Biopsy; D005260:Female; D019788:Fluorodeoxyglucose F18; D051272:Glucose Transporter Type 1 / Q000032:analysis*; D006338:Heart Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D009232:Myxoma / Q000737:chemistry / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor; D051272:Glucose Transporter Type 1; D019275:Radiopharmaceuticals; C495677:SLC2A1 protein, human; D019788:Fluorodeoxyglucose F18