title: Better vaccines for healthier life. Part II. Conference report of the DCVMN International 14th Annual General Meeting Hanoi, Vietnam.
abstract: New vaccines are required to meet the public health challenges of the next generation and many unmet global health needs can be addressed by developing countries vaccine manufacturers such as lower-cost vaccines based on single-dose, thermostable formulations, efficacious in children with compromised gastrointestinal tracts. GMP compliance is also a challenge, as sometimes innovation and clinical development focus is not accompanied by command of scale-up and quality assurance for large volume manufacturing and supply. Identifying and addressing such challenges, beyond cost and cold-chain space, including safety considerations and health worker behavior, regulatory alliances and harmonization to foster access to vaccines, will help countries to ensure sustainable immunization. There needs to be continuous and close management of the global vaccine supply both at national and international levels, requiring careful risk management, coordination and cooperation with manufacturers. Successful partnership models based on sharing a common goal, mutual respect and good communication were discussed among stakeholders.
authors.affiliation: DCVMN International, Chemin du Canal 5, 1260 Nyon, Switzerland. Electronic address: s.pagliusi@dcvmn.org.
authors.forename: Sonia
authors.initials: S
authors.lastname: Pagliusi
authors.affiliation: Biovac Institute, 15 Alexandra Road, Pinelands Cape Town 7430 WP, South Africa. Electronic address: patrick@biovacinstitute.co.za.
authors.forename: Patrick
authors.initials: P
authors.lastname: Tippoo
authors.affiliation: Genome Valley, Shameerpet Mandal, Hyderabad 500078, Andhra Pradesh, India. Electronic address: venkatraman2065@bharatbiotech.com.
authors.forename: Venkatraman
authors.initials: V
authors.lastname: Sivaramakrishnan
authors.affiliation: Vabiotech, Yersin Street, Hanoi, Viet Nam. Electronic address: thuvan@vabiotech.com.vn.
authors.forename: Thuvan
authors.initials: T
authors.lastname: Nguyen
mesh_terms: D003226:Congresses as Topic; D003906:Developing Countries; D014943:Global Health; D007391:International Cooperation; D055818:Public-Private Sector Partnerships; D014612:Vaccines / Q000191:economics / Q000592:standards / Q000600:supply & distribution; D014744:Vietnam
chemical_list: D014612:Vaccines
keywords: GMP compliance; Manufacturing; Quality assurance; Scale-up; Supply-chain