title: [Pit and fissure sealant for caries prevention in 457 children in Uygur city: results of 2-year follow-up].
abstract: OBJECTIVE
  To investigate the 2-year results of pit and fissure sealant in 457 children in Uygur city for caries prevention in the first permanent molars.
  
  
  METHODS
  One thousand four hundred and ninety-nine newly erupted first permanent molars in 457 children between the ages of 7 and 9 in Uygur city underwent pit and fissure sealing using 3M Concisse sealant. The retention of sealants 6, 12 and 24 months after sealing was observed and the caries occurrence were recorded. The data was analyzed with SPSS 16.0 software package.
  
  
  RESULTS
  The retention rate of pit and fissure sealant 6, 12 and 24 months after sealing was 98.33%, 92.71% and 88.93%, respectively. The frequency of dental caries was 0%, 0.63% and 1.15% respectively, which were significantly reduced compared with the average prevalence in China (P<0.05).
  
  
  CONCLUSIONS
  Pit and fissure sealant is safe and effective in preventing dental decay in first permanent molar in Uygur children, which is worthy of wide clinical application. Supported by Comprehensive Intervention Pilot Project for Pediatric Oral Diseases in Middle and Western Area of China in 2010.
authors.affiliation: Dental Clinic, People's Hospital, Uygur Autonomous Region. Urumqi 830001, Xinjiang Autonomous Region;China.E-mail:920327779@qq.com.
authors.forename: Amuti
authors.initials: A
authors.lastname: Riziwaguli
authors.forename: Jing-yu
authors.initials: JY
authors.lastname: Liu
authors.forename: Yi-re
authors.initials: YR
authors.lastname: Ma
authors.forename: Jing
authors.initials: J
authors.lastname: Zou
mesh_terms: D002648:Child; D002681:China; D003731:Dental Caries; D005500:Follow-Up Studies; D006801:Humans; D008963:Molar; D010895:Pit and Fissure Sealants; D014078:Tooth Eruption
chemical_list: D010895:Pit and Fissure Sealants