title: Quantum dots (QDs) based fluorescence probe for the sensitive determination of kaempferol.
abstract: In this work, using the quenching of fluorescence of thioglycollic acid (TGA)-capped CdTe quantum dots (QDs), a novel method for the determination of kaempferol (KAE) has been developed. Under optimum conditions, a linear calibration plot of the quenched fluorescence intensity at 552nm against the concentration of KAE was observed in the range of 4-44μgmL(-1) with a detection limit (3σ/K) of 0.79μgmL(-1). In addition, the detailed reaction mechanism has also been proposed on the basis of electron transfer supported by ultraviolet-visible (UV-vis) absorption and fluorescence (FL) spectroscopy. The method has been applied for the determination of KAE in pharmaceutical preparations with satisfactory results. The proposed method manifested several advantages such as high sensitivity, short analysis time, low cost and ease of operation.
authors.affiliation: School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
authors.forename: Xuanping
authors.initials: X
authors.lastname: Tan
authors.affiliation: School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
authors.forename: Shaopu
authors.initials: S
authors.lastname: Liu
authors.affiliation: School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
authors.forename: Yizhong
authors.initials: Y
authors.lastname: Shen
authors.affiliation: School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
authors.forename: Youqiu
authors.initials: Y
authors.lastname: He
authors.affiliation: School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China; School of Chemistry and Environmental Engineering, Chongqing Three Gorges University, Chongqing, Wanzhou 404000, China. Electronic address: sxyjd7600@sina.com.
authors.forename: Jidong
authors.initials: J
authors.lastname: Yang
mesh_terms: D019187:Cadmium Compounds / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D044949:Kaempferols / Q000032:analysis*; D057230:Limit of Detection; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D045663:Quantum Dots / Q000737:chemistry*; D013050:Spectrometry, Fluorescence / Q000379:methods; D013056:Spectrophotometry, Ultraviolet / Q000379:methods; D013691:Tellurium / Q000737:chemistry*; D013864:Thioglycolates / Q000737:chemistry*
chemical_list: D019187:Cadmium Compounds; D005456:Fluorescent Dyes; D044949:Kaempferols; D004364:Pharmaceutical Preparations; D013864:Thioglycolates; C006552:kaempferol; D013691:Tellurium; C028337:cadmium telluride
keywords: Fluorescence quenching; Kaempferol; TGA-CdTe QDs; Ultraviolet-visible absorption