title: Multiple cutaneous and hepatic hemangiomas in infants.
abstract: OBJECTIVE
  The objectives of the study were to determine the rate of hepatic hemangiomas in infants with cutaneous infantile hemangiomas that were screened by abdominal ultrasound; identify morphological subtypes and number of cutaneous infantile hemangiomas that are likely to suggest the presence of hepatic hemangiomas; and identify clinical history, physical findings, or laboratory abnormalities that may predict hepatic involvement.
  
  
  METHODS
  A retrospective study was conducted between 2000 and 2007 on 37 infants with cutaneous hemangiomas who underwent abdominal ultrasound for hepatic hemangiomas. Infants were classified into subgroups based upon the morphology of their cutaneous hemangioma(s). Data collected included clinical history, physical examination findings, sonographic findings, laboratory results, treatment(s) rendered, and clinical outcome.
  
  
  RESULTS
  Eight of 37 infants (22%) had hepatic hemangiomas. Infants with miliary (30-100 pinpoint/small cutaneous hemangiomas), six or more small cutaneous hemangiomas, and one large with one or more small cutaneous hemangiomas were more likely to have concurrent hepatic hemangiomas. No other clinical findings were associated with hepatic involvement.
  
  
  CONCLUSIONS
  Similar to other studies, our study found clinically asymptomatic hepatic hemangiomas in 22% of infants with multiple cutaneous infantile hemangiomas. No clinical findings studied were predictive of hepatic involvement.
authors.affiliation: From the Section of Dermatology, Children's Mercy Hospitals and Clinics, and the Department of Radiology, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri.
authors.forename: Kristi M
authors.initials: KM
authors.lastname: Canty
authors.affiliation: From the Section of Dermatology, Children's Mercy Hospitals and Clinics, and the Department of Radiology, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri.
authors.forename: Kimberly A
authors.initials: KA
authors.lastname: Horii
authors.affiliation: From the Section of Dermatology, Children's Mercy Hospitals and Clinics, and the Department of Radiology, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri.
authors.forename: Hassan
authors.initials: H
authors.lastname: Ahmad
authors.affiliation: From the Section of Dermatology, Children's Mercy Hospitals and Clinics, and the Department of Radiology, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri.
authors.forename: Lisa H
authors.initials: LH
authors.lastname: Lowe
authors.affiliation: From the Section of Dermatology, Children's Mercy Hospitals and Clinics, and the Department of Radiology, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri.
authors.forename: Amy Jo
authors.initials: AJ
authors.lastname: Nopper
mesh_terms: D005260:Female; D006391:Hemangioma / Q000000981:diagnostic imaging / Q000453:epidemiology*; D006801:Humans; D007223:Infant; D008099:Liver / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology*; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000453:epidemiology*; D014463:Ultrasonography