title: Psychosis in children with systemic lupus erythematosus: the role of steroids as both treatment and cause.
abstract: Steroids may both be a cause of and treatment for pediatric patients with systemic lupus erythematosus (SLE) presenting with psychotic symptoms. We present two cases demonstrating that careful histories (including prior steroid exposure) and the use of biomarkers can help guide the management of children with SLE presenting with psychosis.
authors.affiliation: Department of Child and Adolescent Psychiatry, Children's Hospital of Philadelphia, Philadelphia, PA. Electronic address: alperto@email.chop.edu.
authors.forename: Orna
authors.initials: O
authors.lastname: Alpert
authors.affiliation: Department of Child and Adolescent Psychiatry, Children's Hospital of Philadelphia, Philadelphia, PA.
authors.forename: Raman
authors.initials: R
authors.lastname: Marwaha
authors.affiliation: Department of Psychiatry, Cambridge Health Alliance, Harvard Medical School, Cambridge, MA.
authors.forename: Hsiang
authors.initials: H
authors.lastname: Huang
mesh_terms: D000293:Adolescent; D015415:Biomarkers / Q000097:blood; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000150:complications / Q000188:drug therapy; D011605:Psychoses, Substance-Induced / Q000209:etiology; D011618:Psychotic Disorders / Q000209:etiology*; D013256:Steroids / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D015415:Biomarkers; D013256:Steroids
keywords: Children; Neuropsychiatric lupus; Pediatric; Psychosis; Systemic lupus erythematosus