title: Synthesis of bioactive β-TCP coatings with tailored physico-chemical properties on zirconia bioceramics.
abstract: The objective of this work was to develop a synthesis procedure for the deposition of β-TCP coatings with tailored physico-chemical properties on zirconia bioceramics. The synthesis procedure involved two steps: (i) a rapid wet-chemical deposition of a biomimetic CaP coating and (ii) a subsequent post-deposition processing of the biomimetic CaP coating, which included a heat treatment between 800 and 1200 °C, followed by a short sonication in a water bath. By regulating the heating temperature the topography of the β-TCP coatings could be controlled. The average surface roughness (Ra) ranged from 42 nm for the coating that was heated at 900 °C (TCP-900) to 630 nm for the TCP-1200 coating. Moreover, the heating temperature also affected the dissolution rate of the coatings in a physiological solution, their protein-adsorption capacity and their bioactivity in a simulated body fluid.
authors.affiliation: Engineering Ceramics Department, Jožef Stefan Institute, Ljubljana, Slovenia, martin.stefanic@gmail.com.
authors.forename: Martin
authors.initials: M
authors.lastname: Stefanic
authors.forename: Radmila
authors.initials: R
authors.lastname: Milacic
authors.forename: Goran
authors.initials: G
authors.lastname: Drazic
authors.forename: Miha
authors.initials: M
authors.lastname: Škarabot
authors.forename: Bojan
authors.initials: B
authors.lastname: Budič
authors.forename: Kristoffer
authors.initials: K
authors.lastname: Krnel
authors.forename: Tomaž
authors.initials: T
authors.lastname: Kosmač
mesh_terms: D001826:Body Fluids / Q000737:chemistry; D002130:Calcium Phosphates / Q000138:chemical synthesis / Q000737:chemistry*; D002516:Ceramics / Q000138:chemical synthesis* / Q000737:chemistry; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis* / Q000737:chemistry; D006801:Humans; D008422:Materials Testing / Q000379:methods; D008855:Microscopy, Electron, Scanning; D013499:Surface Properties; D014961:X-Ray Diffraction; D015040:Zirconium / Q000737:chemistry*
chemical_list: D002130:Calcium Phosphates; D020099:Coated Materials, Biocompatible; C485817:beta-tricalcium phosphate; D015040:Zirconium; C028541:zirconium oxide