title: Combination therapy utilizing ketamine and transcranial magnetic stimulation for treatment-resistant depression: a case report.
abstract: In the present article, we report on the case of a 23-year-old woman with a history of treatment-resistant depression who achieved significant symptom improvement with a novel treatment consisting of ketamine, a dissociative anesthetic, and external neuromodulation with transcranial magnetic stimulation (TMS). This case highlights the need for further investigation of treatments pairing external neuromodulation with dissociative anesthetics.
authors.affiliation: 1The Neuroscience Center, Deerfield, IL, USA.
authors.forename: Steven Richard Devore
authors.initials: SR
authors.lastname: Best
authors.forename: Brian
authors.initials: B
authors.lastname: Griffin
mesh_terms: D000778:Anesthetics, Dissociative / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003863:Depression / Q000628:therapy*; D005260:Female; D006801:Humans; D007649:Ketamine / Q000627:therapeutic use*; D011569:Psychiatric Status Rating Scales; D065908:Transcranial Direct Current Stimulation; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000778:Anesthetics, Dissociative; D007649:Ketamine
keywords: depression; ketamine; transcranial magnetic stimulation