title: Bullous mastocytosis mimicking congenital epidermolysis bullosa.
abstract: A 2-month-old female infant was referred to DebRA Mexico from the Regional Children's Hospital because of a generalized dermatosis from birth characterized by multiple blisters and erosions on the trunk, face and limbs, associated with minor trauma. A skin biopsy showing subepidermal blisters associated with a dermal infiltrate of Giemsa-positive cells and CD117-positive antibody was consistent with the diagnosis of bullous mastocytosis. Treatment with oral antihistamines, topical steroids, and antibiotics was initiated, leading to a remission of the lesions.
authors.affiliation: Basic Science Department, School of Medicine, Universidad de Monterrey, Monterrey, Mexico ; Dystrophic Epidermolysis Bullous Research Association Mexico (DebRA Mexico A.C.), Monterrey, Mexico ; Department of Dermatology, University Hospital, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico.
authors.forename: Julio Cesar
authors.initials: JC
authors.lastname: Salas-Alanis
authors.affiliation: Dystrophic Epidermolysis Bullous Research Association Mexico (DebRA Mexico A.C.), Monterrey, Mexico ; Department of Biochemistry and Molecular Medicine, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico.
authors.forename: Cesar Eduard
authors.initials: CE
authors.lastname: Rosales-Mendoza
authors.affiliation: Department of Dermatology, University Hospital, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico.
authors.forename: Jorge
authors.initials: J
authors.lastname: Ocampo-Candiani
keywords: Bullous epidermolysis; Bullous mastocytosis; Darier's sign