title: Cannabinoid-free Cannabis sativa L. grown in the Po valley: evaluation of fatty acid profile, antioxidant capacity and metabolic content.
abstract: Within a project aimed to reintroduce non-drug hemp cultivars in the Italian Po valley, for fibre but also high added-value nutraceutical production, investigation on locally grown plants has been performed, in order to assess their oil and metabolic content. This study provides useful information regarding three different hemp cultivars, from two sites, in view of their potential industrial application. The oil was characterised by a high unsaturated/saturated fatty acid ratio and by an almost perfect balance of ω-3 and ω-6 fatty acids, as requested for healthy foods. The alcoholic extracts, for which a high content of amino acids and phenolic compounds has been highlighted, could provide dietary supplements to help in preventing oxidative stress. By investigating the Carmagnola cultivar, six known and four new lignanamides have been identified, confirming and assessing the general metabolic pattern in the seeds of these locally grown plants.
authors.affiliation: a Dipartimento di Chimica , Università degli Studi di Milano , via C. Golgi 19, 20133 Milano , Italy.
authors.forename: G
authors.initials: G
authors.lastname: Lesma
authors.forename: R
authors.initials: R
authors.lastname: Consonni
authors.forename: V
authors.initials: V
authors.lastname: Gambaro
authors.forename: C
authors.initials: C
authors.lastname: Remuzzi
authors.forename: G
authors.initials: G
authors.lastname: Roda
authors.forename: A
authors.initials: A
authors.lastname: Silvani
authors.forename: V
authors.initials: V
authors.lastname: Vece
authors.forename: G L
authors.initials: GL
authors.lastname: Visconti
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000975:Antioxidants / Q000032:analysis*; D002186:Cannabinoids / Q000032:analysis*; D002188:Cannabis / Q000737:chemistry*; D005227:Fatty Acids / Q000032:analysis*; D007558:Italy; D017705:Lignans / Q000032:analysis; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010636:Phenols / Q000032:analysis; D010938:Plant Oils / Q000737:chemistry; D012639:Seeds / Q000737:chemistry
chemical_list: D000596:Amino Acids; D000975:Antioxidants; D002186:Cannabinoids; D005227:Fatty Acids; D017705:Lignans; D010636:Phenols; D010938:Plant Oils; C093865:cannabisin G
keywords: Cannabis sativa L.; cannabisin; fatty acid; lignanamides; total phenolic