title: Comparison of alveolar ridge preservation methods using three-dimensional micro-computed tomographic analysis and two-dimensional histometric evaluation.
abstract: OBJECTIVE
  This study evaluated the efficacy of alveolar ridge preservation methods with and without primary wound closure and the relationship between histometric and micro-computed tomographic (CT) data.
  
  
  METHODS
  Porcine hydroxyapatite with polytetrafluoroethylene membrane was implanted into a canine extraction socket. The density of the total mineralized tissue, remaining hydroxyapatite, and new bone was analyzed by histometry and micro-CT. The statistical association between these methods was evaluated.
  
  
  RESULTS
  Histometry and micro-CT showed that the group which underwent alveolar preservation without primary wound closure had significantly higher new bone density than the group with primary wound closure (P<0.05). However, there was no significant association between the data from histometry and micro-CT analysis.
  
  
  CONCLUSIONS
  These results suggest that alveolar ridge preservation without primary wound closure enhanced new bone formation more effectively than that with primary wound closure. Further investigation is needed with respect to the comparison of histometry and micro-CT analysis.
authors.affiliation: Department of Oral Anatomy, Seoul National University School of Dentistry, Seoul, Korea.
authors.forename: Young-Seok
authors.initials: YS
authors.lastname: Park
authors.affiliation: Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.
authors.forename: Sungtae
authors.initials: S
authors.lastname: Kim
authors.affiliation: Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.
authors.forename: Seung-Hee
authors.initials: SH
authors.lastname: Oh
authors.affiliation: Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.
authors.forename: Hee-Jung
authors.initials: HJ
authors.lastname: Park
authors.affiliation: Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.
authors.forename: Sophia
authors.initials: S
authors.lastname: Lee
authors.affiliation: Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.
authors.forename: Tae-Il
authors.identifier: 0000-0003-4087-8021
authors.initials: TI
authors.lastname: Kim
authors.affiliation: Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University, Seoul, Korea.
authors.forename: Young-Kyu
authors.initials: YK
authors.lastname: Lee
authors.affiliation: Department of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.
authors.forename: Min-Suk
authors.initials: MS
authors.lastname: Heo
keywords: Bone Substitutes; Polytetrafluoroethylene; X-Ray, Microtomography