title: Naked-eye detection of biologically important anions by a new chromogenic azo-azomethine sensor.
abstract: A new chromogenic azo-azomethine sensor, containing active phenolic sites, has been designed and synthesized via condensation reaction of N,N,N',N'-tetrakis(2-aminoethyl)-2,2-dimethyl propane-1,3-diamine with 1-(3-formyl-4-hydroxyphenylazo)-4-nitrobenzene. The anion recognition ability of the synthesized receptor was evaluated using UV-Vis spectroscopy and (1)H NMR technique. The anion recognition studies exhibited that the receptor acts as a sensor for biologically important anions such as F(-), AcO(-) and H2PO4(-) over other anions. The binding stoichiometry between sensor and anions was found to be 1:2. (1)H NMR experiment revealed that sensor recognizes anions via H-bonds and subsequent deprotonation to elicit a vivid color change. Interestingly, the sensory system not only let for the naked eye detection without any spectroscopic instrumentation but also helped to discriminate between anions.
authors.affiliation: Department of Chemistry, Faculty of Science, Arak University, Arak 38156-8-8349, Iran.
authors.forename: Khatereh
authors.initials: K
authors.lastname: Rezaeian
authors.affiliation: Department of Chemistry, Faculty of Science, Arak University, Arak 38156-8-8349, Iran. Electronic address: h-khanmohammadi@araku.ac.ir.
authors.forename: Hamid
authors.initials: H
authors.lastname: Khanmohammadi
mesh_terms: D000838:Anions / Q000032:analysis*; D001391:Azo Compounds / Q000737:chemistry*; D003124:Colorimetry / Q000379:methods; D004396:Coloring Agents / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D013056:Spectrophotometry, Ultraviolet / Q000379:methods; D013882:Thiosemicarbazones / Q000737:chemistry*
chemical_list: D000838:Anions; D001391:Azo Compounds; D004396:Coloring Agents; D013882:Thiosemicarbazones; C512188:azomethine
keywords: Anion recognition; Azo-azomethine; Chromogenic; Sensor; UV–Vis spectroscopy