title: Ischemic stroke in Greyhounds: 21 cases (2007-2013).
abstract: OBJECTIVE
  To determine the prevalence of ischemic stroke in Greyhounds and determine whether affected dogs had coagulation abnormalities and hypertension.
  
  
  METHODS
  Multi-institutional, retrospective study.
  
  
  METHODS
  21 dogs.
  
  
  METHODS
  Medical records (including diagnostic testing results) and MRI images of the brain were reviewed for Greyhounds with ischemic stroke that had been evaluated at 4 institutions. The proportion of Greyhounds with ischemic stroke was compared with the proportion of non-Greyhound dogs with ischemic stroke. Demographic information for dogs evaluated at each institution was obtained to determine the proportion of Greyhounds in the hospital populations.
  
  
  RESULTS
  21 Greyhounds with ischemic stroke were identified. Abnormalities in coagulation were not identified in the 14 Greyhounds that underwent such testing. Systemic hypertension was identified in 6 of 14 Greyhounds that underwent such testing. No other abnormalities were identified by means of other routine diagnostic tests for Greyhounds. For all institutions combined, the prevalence of ischemic stroke in Greyhounds was 0.66% (21/3,161 Greyhounds). Greyhounds were significantly more likely to be evaluated because of ischemic stroke, compared with all other dog breeds combined (OR, 6.6; 95% confidence interval, 4.2 to 10.2).
  
  
  CONCLUSIONS
  Results of this study suggested that Greyhounds were predisposed to ischemic stroke, compared with all other breeds combined. Coagulation abnormalities did not seem to contribute to ischemic stroke. Hypertension may have contributed to the development of ischemic stroke. Greyhounds with ischemic stroke should undergo measurement of systolic arterial blood pressure. Antihypertensive treatments may be warranted for such dogs.
authors.affiliation: Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602.
authors.forename: Marc
authors.initials: M
authors.lastname: Kent
authors.forename: Eric N
authors.initials: EN
authors.lastname: Glass
authors.forename: Allison C
authors.initials: AC
authors.lastname: Haley
authors.forename: Phillip
authors.initials: P
authors.lastname: March
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Rozanski
authors.forename: Evelyn M
authors.initials: EM
authors.lastname: Galban
authors.forename: Abagail
authors.initials: A
authors.lastname: Bertalan
authors.forename: Simon R
authors.initials: SR
authors.lastname: Platt
mesh_terms: D000818:Animals; D002545:Brain Ischemia / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D008297:Male; D012189:Retrospective Studies; D020521:Stroke / Q000473:pathology / Q000662:veterinary*