title: A case report of acute severe paraquat poisoning and long-term follow-up.
abstract: In the present study, the successful management of severe paraquat (PQ) poisoning with multiple organ dysfunction syndrome is described. A 42-year-old female ingested >100 ml PQ (20% weight/volume) in an attempted suicide. After 22 h the patient was admitted to hospital with serious liver, kidney and lung damage. Comprehensive therapy that maximized poison elimination was administered, along with appropriate glucocorticoids and medication for anticoagulation and protection of the liver and kidney. The patient was successfully treated and recovered after 40 days. However, pulmonary damage was aggravated when the glucocorticoid treatment was stopped after 2 months; the lungs recovered again following systematic therapy. Subsequent to a 8-month follow-up, the patient was able to look after herself in her daily life. To the best of our knowledge, successful treatment following severe PQ poisoning is rare.
authors.affiliation: Department of Poisoning and Occupational Diseases, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
authors.forename: Guangcai
authors.initials: G
authors.lastname: Yu
authors.affiliation: Department of Poisoning and Occupational Diseases, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
authors.forename: Baotian
authors.initials: B
authors.lastname: Kan
authors.affiliation: Department of Poisoning and Occupational Diseases, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
authors.forename: Xiangdong
authors.initials: X
authors.lastname: Jian
authors.affiliation: Department of Poisoning and Occupational Diseases, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
authors.forename: Jieru
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Poisoning and Occupational Diseases, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
authors.forename: Jing
authors.initials: J
authors.lastname: Sun
authors.affiliation: Department of Poisoning and Occupational Diseases, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
authors.forename: Chengzhen
authors.initials: C
authors.lastname: Song
keywords: acute paraquat poisoning; long-term follow; treatment