title: Predictors of mesorectal fascia invasion after gadolinium injection in rectal carcinoma after neoadjuvant therapy.
abstract: OBJECTIVE
  To assess spectral presaturation inversion-recovery MRI sequence with gadolinium to identify predictors of mesorectal fascia (MRF) invasion in patients with locally advanced rectal carcinoma after neoadjuvant therapy.
  
  
  METHODS
  Sixty-five patients underwent neoadjuvant concomitant radiation and chemotherapy and surgery. Magnetic resonance images were assessed by two radiologists.
  
  
  RESULTS
  Linear (odds ratio, 95% confidence intervals: 19.33, 1.98-188.6) and reticular strands (odds ratio, 95% confidence intervals: 9.75, 1.45-67.77) reaching the MRF are predictors of MRF invasion.
  
  
  CONCLUSIONS
  Linear or reticular mesorectal strands reaching the MRF detected at contrast-enhanced MRI represent a predictor of MRF invasion.
authors.affiliation: Department of Radiology, Cattinara Hospital, University of Trieste, Strada di Fiume 447, 34149, Trieste, Italy. Electronic address: quaia@units.it.
authors.forename: Emilio
authors.initials: E
authors.lastname: Quaia
authors.affiliation: Department of Radiology, Cattinara Hospital, University of Trieste, Strada di Fiume 447, 34149, Trieste, Italy.
authors.forename: Antonio Giulio
authors.initials: AG
authors.lastname: Gennari
authors.affiliation: Department of Radiology, Cattinara Hospital, University of Trieste, Strada di Fiume 447, 34149, Trieste, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: De Paoli
authors.affiliation: Department of Radiology, Cattinara Hospital, University of Trieste, Strada di Fiume 447, 34149, Trieste, Italy.
authors.forename: Roberta
authors.initials: R
authors.lastname: Angileri
authors.affiliation: Department of Radiology, Cattinara Hospital, University of Trieste, Strada di Fiume 447, 34149, Trieste, Italy.
authors.forename: Maja
authors.initials: M
authors.lastname: Ukmar
authors.affiliation: Department of Radiology, Cattinara Hospital, University of Trieste, Strada di Fiume 447, 34149, Trieste, Italy.
authors.forename: Maria Assunta
authors.initials: MA
authors.lastname: Cova
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media / Q000008:administration & dosage; D005205:Fascia / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D005682:Gadolinium / Q000008:administration & dosage; D006571:Heterocyclic Compounds / Q000008:administration & dosage*; D006801:Humans; D015552:Injections, Intralesional; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging / Q000379:methods*; D009942:Organometallic Compounds / Q000008:administration & dosage*; D011237:Predictive Value of Tests; D012004:Rectal Neoplasms / Q000175:diagnosis* / Q000628:therapy; D015203:Reproducibility of Results; D012189:Retrospective Studies
chemical_list: D003287:Contrast Media; D006571:Heterocyclic Compounds; D009942:Organometallic Compounds; C062402:gadoteridol; D005682:Gadolinium
keywords: Magnetic resonance imaging; Mesorectal fascia; Neoadjuvant therapy; Rectal cancer