title: Colposcopy: gynecological vision in viewing oral lesions.
abstract: BACKGROUND
  The diagnosis of malignant and potentially malignant epithelial lesions of the oral mucosa cannot be based solely on clinical findings. The histologic evaluation of a representative biopsy specimen thus becomes necessary. The site for biopsy however is always a subjective choice that sometimes raises doubts about its representativeness. So far, no simple and reliable method is available for the selection of the most appropriate area for biopsy. Colposcopy is helpful in the selection of these sites of epithelial dysplasia depending upon the vascular patterns.
  
  
  OBJECTIVE
  This study was planned to assess the role of Colposcopic examination in the selection of biopsy site in patients with varying grades of oral epithelial dysplasia at various sites.
  
  
  METHODS
  One hundred and eighty patients between the ages of 30 and 60 years clinically diagnosed with leukoplakia and carcinoma buccal mucosa were included in the study.
  
  
  METHODS
  For each of the subjects, a thorough clinical examination followed by Colposcopic assessment was carried out for the selection of biopsy site from the involved mucosa. The histopathological findings were then compared in the two cases and results analyzed.
  
  
  METHODS
  The statistical analysis was performed using a paired t-test.
  
  
  RESULTS
  In our study, sensitivity and specificity for the selection of biopsy site by Colposcopic examination was found to be higher for leukoplakia than for carcinoma buccal mucosa.
  
  
  CONCLUSIONS
  It was concluded that Colposcopic examination was found to be significant in the selection of biopsy site for leukoplakia while clinical criterion was found to be more appropriate for carcinoma buccal mucosa cases.
authors.affiliation: Department of Oral Medicine and Radiology, Government Dental College and Research Institute, Bangalore, Karnataka, India.
authors.forename: Abhishek Singh
authors.initials: AS
authors.lastname: Nayyar
authors.forename: Mubeen
authors.initials: M
authors.lastname: Khan
authors.forename: U D
authors.initials: UD
authors.lastname: Bafna
authors.forename: Ahmed
authors.initials: A
authors.lastname: Siddique
authors.forename: H C
authors.initials: HC
authors.lastname: Gayitri
mesh_terms: D000328:Adult; D001706:Biopsy; D002277:Carcinoma / Q000175:diagnosis*; D003127:Colposcopy / Q000379:methods*; D005260:Female; D006801:Humans; D007972:Leukoplakia, Oral / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000175:diagnosis*; D012680:Sensitivity and Specificity