title: Metastatic ovarian sex-cord stromal tumor with annular tubules in a patient without Peutz-Jeghers syndrome.
abstract: Sex-cord stromal tumors (SCSTs) with annular tubules (SCTATs) are a small class of ovarian lesions that possess histologic features of both Sertoli and granulosa cells. Approximately one-third of patients with SCTAT also have Peutz-Jaghers syndreome, which makes these cases especially rare. Patients with non-PJS-associated SCTAT make up the remaining two-thirds; 20% of these cases have a metastatic presentation. Metastasis of these tumors to the head and neck region has only been reported in a few instances. In this article we report a case of a 25-year-old woman who presented with "a lump in her throat" and was ultimately diagnosed with SCTAT. We also discuss the current protocols in the diagnosis and treatment of this entity.
authors.affiliation: Department of Otolaryngology, St. John Oakland Hospital, 27483 Dequindre Rd., Suite 201, Madison Heights, MI 48071, USA. kdartoo7@yahoo.com.
authors.forename: Kimi
authors.initials: K
authors.lastname: Dart
authors.forename: Ted
authors.initials: T
authors.lastname: Schwartzenfeld
authors.forename: Warren
authors.initials: W
authors.lastname: Brandes
authors.forename: Anthony
authors.initials: A
authors.lastname: D'Errico
authors.forename: Michael
authors.initials: M
authors.lastname: Stender
mesh_terms: D000328:Adult; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000556:secondary*; D006801:Humans; D010051:Ovarian Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D010580:Peutz-Jeghers Syndrome / Q000150:complications; D018312:Sex Cord-Gonadal Stromal Tumors / Q000150:complications / Q000188:drug therapy / Q000556:secondary*