title: Usefulness of resistive index on spectral Doppler ultrasonography in the detection of renal cell carcinoma in patients with end-stage renal disease.
abstract: OBJECTIVE
  The aim of this study was to explore the usefulness of the resistive index (RI) on spectral Doppler ultrasonography (US) in the detection of renal cell carcinoma (RCC) in patients with end-stage renal disease (ESRD).
  
  
  METHODS
  Seventeen ESRD patients with kidneys in which renal masses were suspected in routine US were subjected. They underwent computed tomography scans and additional Doppler US for the characterization of the detected lesions. All underwent radical nephrectomy with the suspicion of RCC. Fourteen patients finally were included. RI measurements were conducted in the region of the suspected renal mass and the background renal parenchyma. The intraclass correlation coefficient was used to assess the reproducibility of the RI measurement. A paired t-test was used to compare the RI values between the renal mass and the background renal parenchyma (P<0.05).
  
  
  RESULTS
  The RI values measured at the RCCs were significantly lower than those measured at the background renal parenchyma (0.41-0.65 vs. 0.75-0.89; P<0.001). The intrareader reproducibility proved to be excellent and good for the renal masses and the parenchyma, respectively (P<0.001).
  
  
  CONCLUSIONS
  RI on spectral Doppler US is useful in detecting RCC in patients with ESRD. The RI values measured at the RCCs were significantly lower than those measured at the background renal parenchyma.
authors.affiliation: Department of Radiology, Seoul National University Hospital, Seoul, Korea.
authors.forename: Sang Youn
authors.identifier: 0000-0003-4038-7345
authors.initials: SY
authors.lastname: Kim
authors.affiliation: Department of Radiology, Seoul National University Hospital, Seoul, Korea.
authors.forename: Sungmin
authors.identifier: 0000-0001-8459-8369
authors.initials: S
authors.lastname: Woo
authors.affiliation: Department of Radiology, Seoul National University Boramae Hospital, Seoul, Korea.
authors.forename: Sung Il
authors.identifier: 0000-0001-7516-5369
authors.initials: SI
authors.lastname: Hwang
authors.affiliation: Department of Radiology, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Min Hoan
authors.identifier: 0000-0003-2448-2895
authors.initials: MH
authors.lastname: Moon
authors.affiliation: Department of Radiology, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Chang Kyu
authors.identifier: 0000-0003-4922-5107
authors.initials: CK
authors.lastname: Sung
authors.affiliation: Department of Radiology, Seoul National University Boramae Hospital, Seoul, Korea.
authors.forename: Hak Jong
authors.identifier: 0000-0003-0858-7873
authors.initials: HJ
authors.lastname: Lee
authors.affiliation: Department of Radiology, Seoul National University Hospital, Seoul, Korea ; Department of Radiology, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Jeong Yeon
authors.identifier: 0000-0001-8659-0918
authors.initials: JY
authors.lastname: Cho
authors.affiliation: Department of Radiology, Seoul National University Hospital, Seoul, Korea ; Department of Radiology, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Seung Hyup
authors.identifier: 0000-0002-9339-5907
authors.initials: SH
authors.lastname: Kim
keywords: Carcinoma, renal cell; Kidney failure, chronic; Ultrasonography, Doppler, color; Ultrasonography, Doppler, pulsed