title: Laryngeal actinomycosis in an immunocompromised patient.
abstract: Actinomycosis of the larynx represents an unusual presentation for a common bacterium comprising the oral and oropharyngeal florae. There are few cases reported in the literature of laryngeal actinomycosis occurring primarily in the immunocompromised population. Here, we present a case in a 74-year-old man that occurred in the setting of neutropenia as a result of chemotherapy. Once the diagnosis was made with biopsy of the larynx, the infection was resolved after a prolonged course of penicillin-based therapy.
authors.affiliation: Division of Laryngology, Department of Otolaryngology-Head and Neck Surgery, University of Florida Health, Gainesville, Florida.
authors.forename: Sheylan
authors.initials: S
authors.lastname: Patel
authors.affiliation: Division of Laryngology, Department of Otolaryngology-Head and Neck Surgery, University of Florida Health, Gainesville, Florida.
authors.forename: Aaron J
authors.initials: AJ
authors.lastname: Jaworek
authors.affiliation: Division of Laryngology, Department of Otolaryngology-Head and Neck Surgery, University of Florida Health, Gainesville, Florida.
authors.forename: Vatsal
authors.initials: V
authors.lastname: Patel
authors.affiliation: Division of Laryngology, Department of Otolaryngology-Head and Neck Surgery, University of Florida Health, Gainesville, Florida.
authors.forename: Lizette Vila
authors.initials: LV
authors.lastname: Duckworth
authors.affiliation: Division of Laryngology, Department of Otolaryngology-Head and Neck Surgery, University of Florida Health, Gainesville, Florida.
authors.forename: Raja
authors.initials: R
authors.lastname: Sawhney
authors.affiliation: Division of Laryngology, Department of Otolaryngology-Head and Neck Surgery, University of Florida Health, Gainesville, Florida. Electronic address: Neil.Chheda@ent.ufl.edu.
authors.forename: Neil N
authors.initials: NN
authors.lastname: Chheda
mesh_terms: D000196:Actinomycosis / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology* / Q000382:microbiology; D000368:Aged; D019980:Amoxicillin-Potassium Clavulanate Combination / Q000008:administration & dosage; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D001706:Biopsy; D002939:Ciprofloxacin / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D006801:Humans; D016867:Immunocompromised Host; D007818:Laryngeal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology* / Q000382:microbiology; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy* / Q000276:immunology; D008297:Male; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin; D019980:Amoxicillin-Potassium Clavulanate Combination
keywords: Actinomycosis; Immunocompromised; Larynx; Neutropenia