title: An unexpected role: UVA-induced release of nitric oxide from skin may have unexpected health benefits.
abstract: UVR has deleterious and beneficial effects on human health. In this issue, Liu et al. (2014) show that UVA decreases blood pressure and increases blood flow and heart rate in humans, which is beneficial to the cardiovascular system. This is likely mediated by UVA causing release of nitric oxide (NO) from skin stores. This mediator may have additional effects on human health.
authors.affiliation: Dermatology, Bosch Institute, Sydney Cancer Centre, University of Sydney, Sydney, New South Wales, Australia. Electronic address: gary.halliday@sydney.edu.au.
authors.forename: Gary M
authors.initials: GM
authors.lastname: Halliday
authors.affiliation: Dermatology, Bosch Institute, Sydney Cancer Centre, University of Sydney, Sydney, New South Wales, Australia; Infectious Diseases and Immunology, Bosch Institute, Sydney Cancer Centre, University of Sydney, New South Wales, Sydney, Australia.
authors.forename: Scott N
authors.initials: SN
authors.lastname: Byrne
mesh_terms: D001794:Blood Pressure / Q000528:radiation effects*; D005260:Female; D006801:Humans; D008297:Male; D019001:Nitric Oxide Synthase / Q000378:metabolism*; D012867:Skin / Q000098:blood supply* / Q000528:radiation effects*; D014466:Ultraviolet Rays; D014664:Vasodilation / Q000528:radiation effects*
chemical_list: D019001:Nitric Oxide Synthase