title: Successful treatment of rhabdomyolysis and acute renal failure following amoxapine overdose.
abstract: Amoxapine, a tricyclic antidepressant, is widely used by psychiatrists. While overdose of tricyclic antidepressants is known to be dangerous and potentially fatal (causing hypotension, arrhythmia, convulsions, respiratory failure, and other serious complications), overdose of amoxapine can cause other problems, and metabolic acidosis, seizures, neuroleptic malignant syndrome, and arrhythmia have been reported. This report describes the case of a patient who developed rhabdomyolysis and acute renal failure following amoxapine overdose. Continuous hemofiltration was instituted twice, and he recovered without sequelae; this suggests the effectiveness of continuous hemofiltration and its possibilities in the treatment of amoxapine overdose and acute renal failure due to rhabdomyolysis.
authors.forename: J
authors.initials: J
authors.lastname: Shigemura Tatsuro Kuwahara Soichiro Nomura Akimitsu Yokoyama Hideki Uemura
keywords: Amoxapine Rhabdomyolysis Continuous Hemofiltration Overdose Acute Renal Failure