title: Metabolic syndrome as a risk factor for elevated intraocular pressure.
abstract: OBJECTIVE
  The aim of this study was to investigate the association between intraocular pressure and metabolic syndrome by comparing central corneal thicknesses.
  
  
  METHODS
  One hundred sixty-two subjects were enrolled in this cross-sectional study, with 89 subjects in a metabolic syndrome group and 73 subjects in a control group. Ophthalmological examinations, including intraocular pressure and central corneal thickness measurements, were performed on each subject. Serum fasting glucose, triglyceride and HDL cholesterol levels were measured, and waist circumference, systolic and diastolic blood pressure of all patients were recorded.
  
  
  RESULTS
  Participants with metabolic syndrome had a significantly higher intraocular pressure than those without metabolic syndrome (p = 0.008), and there was no statistically significant difference between the central corneal thicknesses of the two groups (p = 0.553). Most of the metabolic syndrome components were associated with higher intraocular pressure (p < 0.05).
  
  
  CONCLUSIONS
  There is a relationship between metabolic syndrome and intraocular pressure, but no association between metabolic syndrome and central corneal thicknesses. Intraocular pressure is affected by central corneal thicknesses, and intraocular pressure is used to correct according to the central corneal thicknesses measurement. To our knowledge, this is the first study that determines the positive relationship between metabolic syndrome and intraocular pressure by comparing the central corneal thicknesses of the groups.
authors.affiliation: Nedime Sahinoglu-Keskek, MD, Department of Ophthalmology, Numune Training and Research Hospital, Adana, Turkey.
authors.forename: Nedime
authors.initials: N
authors.lastname: Sahinoglu-Keskek
authors.affiliation: Sakir Ozgur Keskek, MD, Department of Internal Medicine, Numune Training and Research Hospital, Adana, Turkey.
authors.forename: Sakir Ozgur
authors.initials: SO
authors.lastname: Keskek
authors.affiliation: Selim Cevher, MD, Department of Ophthalmology, Numune Training and Research Hospital, Adana, Turkey.
authors.forename: Selim
authors.initials: S
authors.lastname: Cevher
authors.affiliation: Sinan Kirim, MD, Department of Internal Medicine, Numune Training and Research Hospital, Adana, Turkey.
authors.forename: Sinan
authors.initials: S
authors.lastname: Kirim
authors.affiliation: Asim Kayiklik, MD, Department of Ophthalmology, Numune Training and Research Hospital, Adana, Turkey.
authors.forename: Asim
authors.initials: A
authors.lastname: Kayiklik
authors.affiliation: Gulay Ortoglu, MD, Department of Internal Medicine, Numune Training and Research Hospital, Adana, Turkey.
authors.forename: Gulay
authors.initials: G
authors.lastname: Ortoglu
authors.affiliation: Tayyibe Saler, Assistant Professor, Department of Internal Medicine, Numune Training and Research Hospital, Adana, Turkey.
authors.forename: Tayyibe
authors.initials: T
authors.lastname: Saler
keywords: Central corneal thickness; Glaucoma; Intraocular pressure; Metabolic syndrome