title: Timing protein assembly in neurons.
abstract: Integration of two fluorescence imaging methods enables tracking of the formation of fibrillar Aβ peptide amyloid aggregates in neurons, as discussed by Esbjörner and colleagues in this issue of Chemistry & Biology. This approach has the potential to fundamentally improve our understanding of the onset and therapeutic intervention of neurodegenerative diseases.
authors.affiliation: Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany. Electronic address: m.sauer@uni-wuerzburg.de.
authors.forename: Markus
authors.initials: M
authors.lastname: Sauer
mesh_terms: D016229:Amyloid beta-Peptides / Q000378:metabolism*; D006801:Humans; D010446:Peptide Fragments / Q000378:metabolism*; D066329:Protein Aggregates; D066263:Protein Aggregation, Pathological
chemical_list: D016229:Amyloid beta-Peptides; D010446:Peptide Fragments; D066329:Protein Aggregates; C078592:amyloid beta-protein (1-40); C075222:amyloid beta-protein (1-42)