title: Organochlorine pesticide level differences among female inhabitants from Veracruz, Puebla and Tabasco, Mexico.
abstract: Organochlorine pesticides have been used in Mexico in malaria control programs and against ectoparasites. The objective of this study was to compare the levels of organochlorine pesticides: HCB, α-β-γ-HCH, pp'-DDE, op'-DDT and pp'-DDT in adipose tissue of female inhabitants from three Mexican states: Veracruz, Puebla and Tabasco. Data analyses indicated higher β-HCH levels in Puebla inhabitants. When comparing the mean values of the pp'-DDE concentrations among the three states, no statistically significant differences were noted. A trend of increasing concentrations of op'-DDT from Veracruz to Puebla and Tabasco was observed. Significantly higher pp'-DDT concentrations in Veracruz as compared to Puebla and Tabasco were determined. Using factorial analysis of three age categories (>30, 31-50, <51) organochlorine pesticide concentrations increases with age of participants, indicating time of exposure as a principal factor of organochlorine pesticides accumulation in adipose tissue.
authors.affiliation: Institute of Forensic Medicine, University of Veracruz, SS Juan Pablo II s/n, 94290, Boca del Rio, Vercaruz, Mexico, swal@uv.mx.
authors.forename: Stefan M
authors.initials: SM
authors.lastname: Waliszewski
authors.forename: M
authors.initials: M
authors.lastname: Caba
authors.forename: H
authors.initials: H
authors.lastname: Saldarriaga-Noreña
authors.forename: A J
authors.initials: AJ
authors.lastname: Martínez
authors.forename: E
authors.initials: E
authors.lastname: Meza
authors.forename: R
authors.initials: R
authors.lastname: Valencia Quintana
authors.forename: R
authors.initials: R
authors.lastname: Zepeda
mesh_terms: D000273:Adipose Tissue / Q000737:chemistry / Q000378:metabolism*; D000328:Adult; D003634:DDT / Q000032:analysis* / Q000378:metabolism; D003633:Dichlorodiphenyl Dichloroethylene / Q000032:analysis* / Q000378:metabolism; D004781:Environmental Exposure / Q000032:analysis*; D005260:Female; D001556:Hexachlorocyclohexane / Q000032:analysis* / Q000378:metabolism; D006801:Humans; D008288:Malaria / Q000517:prevention & control; D008800:Mexico; D008875:Middle Aged; D010573:Pesticide Residues / Q000032:analysis / Q000378:metabolism; D010575:Pesticides / Q000032:analysis* / Q000378:metabolism
chemical_list: D010573:Pesticide Residues; D010575:Pesticides; C040534:alpha-hexachlorocyclohexane; D003633:Dichlorodiphenyl Dichloroethylene; D001556:Hexachlorocyclohexane; D003634:DDT; C023888:beta-hexachlorocyclohexane