title: Enantioselective rhodium-catalyzed arylation of cyclic N-sulfamidate alkylketimines: a new access to chiral β-alkyl-β-aryl amino alcohols.
abstract: The enantioselective rhodium-catalyzed 1,2-addition of arylboronates to cyclic N-sulfamidate alkylketimines was developed. With a rhodium/diene complex as catalyst, high enantioselectivity and broad functional group tolerance were observed. The resulting sulfamidates can easily be converted into chiral β-alkyl-β-aryl amino alcohols.
authors.affiliation: CAS Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , Shanghai 200032, P. R. China.
authors.forename: Ya-Jing
authors.initials: YJ
authors.lastname: Chen
authors.forename: Ya-Heng
authors.initials: YH
authors.lastname: Chen
authors.forename: Chen-Guo
authors.initials: CG
authors.lastname: Feng
authors.forename: Guo-Qiang
authors.initials: GQ
authors.lastname: Lin