title: An increased incidence of total anomalous pulmonary venous connection among Hispanics in southern Nevada.
abstract: OBJECTIVE
  Ethnicity may influence the occurrence of specific cardiac malformations.
  
  
  METHODS
  We retrospectively analyzed the occurrence of isolated total anomalous pulmonary venous connection in the Hispanic and non-Hispanic populations of Southern Nevada over a 10-year period from 2003 to 2013.
  
  
  RESULTS
  The mean cases per 100,000 live births among Hispanics was 19.8 (99% confidence interval 5.9-33.7) and among non-Hispanics was 2.5 (99% confidence interval 0.4-4.6), P = 0.007.
  
  
  CONCLUSIONS
  We found a significantly higher incidence of isolated total anomalous pulmonary venous connection in Hispanics vs. non-Hispanics.
authors.affiliation: Pediatric Cardiology Division, Children's Heart Center, Las Vegas, Nev, USA; School of Medicine, Department of Pediatrics, Division of Cardiology, University of Nevada, Las Vegas, Nev, USA.
authors.forename: William N
authors.initials: WN
authors.lastname: Evans
authors.forename: Ruben J
authors.initials: RJ
authors.lastname: Acherman
authors.forename: Michael L
authors.initials: ML
authors.lastname: Ciccolo
authors.forename: William J
authors.initials: WJ
authors.lastname: Castillo
authors.forename: Humberto
authors.initials: H
authors.lastname: Restrepo
mesh_terms: D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D008297:Male; D009505:Nevada / Q000453:epidemiology; D012189:Retrospective Studies; D012587:Scimitar Syndrome / Q000453:epidemiology*
keywords: Amerindian Genetics; Cardiac Malformation Incidence; Hispanics; Total Anomalous Pulmonary Venous Connection