title: [Construction of research system for processing mechanism of traditional Chinese medicine based on chemical composition transformation combined with intestinal absorption barrier].
abstract: Based on practice of Epimedium processing mechanism for many years and integrated multidisciplinary theory and technology, this paper initially constructs the research system for processing mechanism of traditional Chinese medicine based on chemical composition transformation combined with intestinal absorption barrier, which to form an innovative research mode of the " chemical composition changes-biological transformation-metabolism in vitro and in vivo-intestinal absorption-pharmacokinetic combined pharmacodynamic-pharmacodynamic mechanism". Combined with specific examples of Epimedium and other Chinese herbal medicine processing mechanism, this paper also discusses the academic thoughts, research methods and key technologies of this research system, which will be conducive to systematically reveal the modem scientific connotation of traditional Chinese medicine processing, and enrich the theory of Chinese herbal medicine processing.
authors.forename: E
authors.initials: E
authors.lastname: Sun
authors.forename: Feng-Juan
authors.initials: FJ
authors.lastname: Xu
authors.forename: Zhen-Hai
authors.initials: ZH
authors.lastname: Zhang
authors.forename: Ying-Jie
authors.initials: YJ
authors.lastname: Wei
authors.forename: Xiao-Bin
authors.initials: XB
authors.lastname: Tan
authors.forename: Xu-Dong
authors.initials: XD
authors.lastname: Cheng
authors.forename: Xiao-Bin
authors.initials: XB
authors.lastname: Jia
mesh_terms: D000818:Animals; D004339:Drug Compounding / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000378:metabolism* / Q000493:pharmacokinetics / Q000494:pharmacology; D034181:Epimedium / Q000737:chemistry*; D007408:Intestinal Absorption; D008516:Medicine, Chinese Traditional / Q000379:methods*
chemical_list: D004365:Drugs, Chinese Herbal