title: Synthesis and fungicidal activity of novel chloro-containing 1-aryl-3-oxypyrazoles with an oximino ester or oximino amide moiety.
abstract: Six novel chloro-containing 1-aryl-3-oxypyrazoles TMa-TMf with an oximino ester or an oximino amide moiety were prepared by the reaction of 1-aryl-1H-pyrazol-3-ols with benzyl bromide. Their structures were characterized by 1H-NMR, 13C-NMR, IR, MS, and elemental analysis. A preliminary in vitro bioassay indicated that compounds TMa, TMe and TMf displayed excellent fungicidal activity against Rhizoctonia solani and could be used as potential lead compounds for further development of novel fungicides.
authors.affiliation: Department of Chemical and Pharmaceutical Engineering, Southeast University ChengXian College, Nanjing 210088, China. liuyuanyuan1985419@163.com.
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Liu
authors.affiliation: College of Food Science and Light Industry, Nanjing Tech University, Nanjing 211816, China. liynj2012@njtech.edu.cn.
authors.forename: Yi
authors.initials: Y
authors.lastname: Li
authors.affiliation: College of Science, Nanjing Tech University, Nanjing 211816, China.
authors.forename: Nanqing
authors.initials: N
authors.lastname: Chen
authors.affiliation: College of Science, Nanjing Tech University, Nanjing 211816, China.
authors.forename: Kunzhi
authors.initials: K
authors.lastname: Lv
authors.affiliation: Department of Chemical and Pharmaceutical Engineering, Southeast University ChengXian College, Nanjing 210088, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Zhou
authors.affiliation: College of Food Science and Light Industry, Nanjing Tech University, Nanjing 211816, China.
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Xiong
authors.affiliation: College of Science, Nanjing Tech University, Nanjing 211816, China.
authors.forename: Fangshi
authors.initials: F
authors.lastname: Li
mesh_terms: D005659:Fungicides, Industrial / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D011720:Pyrazoles / Q000737:chemistry*; D012232:Rhizoctonia / Q000187:drug effects; D013329:Structure-Activity Relationship
chemical_list: D005659:Fungicides, Industrial; D011720:Pyrazoles; C031280:pyrazole