title: Structural and functional correlates of epileptogenesis - does gender matter?
abstract: In the majority of neuropsychiatric conditions, marked gender-based differences have been found in the epidemiology, clinical manifestations, and therapy of disease. One possible reason is that sex differences in cerebral morphology, structural and functional connections, render men and women differentially vulnerable to various disease processes. The present review addresses this issue with respect to the functional and structural correlates to some forms of epilepsy.
authors.affiliation: Department of Women's and Children's Health, Karolinska Institute and Neurology Clinic, Karolinska University Hospital, Sweden. Electronic address: ivanka.savic-berglund@ki.se.
authors.forename: Ivanka
authors.initials: I
authors.lastname: Savic
authors.affiliation: Department of Neurology, David Geffen School of Medicine at UCLA, USA; Department of Neurobiology, David Geffen School of Medicine at UCLA, USA; Department of Psychiatry & Biobehavioral Sciences, David Geffen School of Medicine at UCLA, USA; The Brain Research Institute, David Geffen School of Medicine at UCLA, USA.
authors.forename: Jerome
authors.initials: J
authors.lastname: Engel
mesh_terms: D000818:Animals; D001921:Brain / Q000503:physiopathology*; D004827:Epilepsy / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D012727:Sex Characteristics
keywords: Cerebral connectivity; Generalized epilepsy; MRI; MTLE; Seizures; Sex difference