title: Direct analysis of large living organism by megavolt electrostatic ionization mass spectrometry.
abstract: A new ambient ionization method allowing the direct chemical analysis of living human body by mass spectrometry (MS) was developed. This MS method, namely Megavolt Electrostatic Ionization Mass Spectrometry, is based on electrostatic charging of a living individual to megavolt (MV) potential, illicit drugs, and explosives on skin/glove, flammable solvent on cloth/tissue paper, and volatile food substances in breath were readily ionized and detected by a mass spectrometer.
authors.affiliation: Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Hong Kong, People's Republic of China, kwanmng@hku.hk.
authors.forename: Kwan-Ming
authors.initials: KM
authors.lastname: Ng
authors.forename: Ho-Wai
authors.initials: HW
authors.lastname: Tang
authors.forename: Sin-Heng
authors.initials: SH
authors.lastname: Man
authors.forename: Pui-Yuk
authors.initials: PY
authors.lastname: Mak
authors.forename: Yi-Ching
authors.initials: YC
authors.lastname: Choi
authors.forename: Melody Yee-Man
authors.initials: MY
authors.lastname: Wong
mesh_terms: D000082:Acetaminophen / Q000032:analysis; D018712:Analgesics, Non-Narcotic / Q000032:analysis; D000779:Anesthetics, Local / Q000032:analysis; D001944:Breath Tests / Q000295:instrumentation / Q000379:methods; D003042:Cocaine / Q000032:analysis; D004867:Equipment Design; D053834:Explosive Agents / Q000032:analysis*; D017575:Gloves, Protective; D006801:Humans; D013287:Illicit Drugs / Q000032:analysis*; D010209:Paper; D021241:Spectrometry, Mass, Electrospray Ionization / Q000295:instrumentation / Q000379:methods*; D055672:Static Electricity; D055549:Volatile Organic Compounds / Q000032:analysis
chemical_list: D018712:Analgesics, Non-Narcotic; D000779:Anesthetics, Local; D053834:Explosive Agents; D013287:Illicit Drugs; D055549:Volatile Organic Compounds; D000082:Acetaminophen; D003042:Cocaine