title: Histological evaluation of pulp tissue from second primary molars correlated with clinical and radiographic caries findings.
abstract: BACKGROUND
  Managing dental caries in young children is demanding due to the elusions present on the right diagnostic criteria for treatment. The present study evaluated the histological status of pulp tissues extracted from primary second molar with caries involvement. Histological findings are correlated with clinical and radiographic assessment.
  
  
  METHODS
  Simple experimental study was conducted on upper or lower second primary molars with occlusal (22 teeth) or proximal (22 teeth) dental caries. Selected children were below 6 years of age. Percentage of caries involvement, residual dentin thickness (RDT), radiographic assessment of interradicular and periapical areas, clinical caries depth and signs and symptoms are the parameters considered for comparing with the histological findings. The specimens were grouped based on the nature of the inflammatory process as acute or chronic. The data were analyzed by Student t-test to compare histological types of inflammation with clinical parameters. P value < 0.05 was considered as significant.
  
  
  RESULTS
  Four cases revealed severe acute inflammation in coronal and relatively mild acute inflammation in radicular pulp. In the rest of the specimen coronal and radicular pulp had similar acute or chronic inflammatory changes. Histological evidence of pulpitis correlated with dental caries depth of ≥80%, RDT of ≤1 mm, radiographic rarefactions in the interradicular regions and symptoms of pain.
  
  
  CONCLUSIONS
  Primary second molars with more than two-third caries involvement with symptoms of pain histologically showed inflammation of both coronal and radicular pulp tissues in all cases.
authors.affiliation: General and Specialist Dental Practice, College of Dentistry, University of Sharjah, Sharjah, United Arab Emirates.
authors.forename: Vellore Kannan
authors.initials: VK
authors.lastname: Gopinath
authors.affiliation: Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates.
authors.forename: Khurshid
authors.initials: K
authors.lastname: Anwar
keywords: Caries; deciduous; dental pulp; immunohistochemistry; inflammation