title: Reproducibility of the Carpet View system: a novel technical solution for display and off line analysis of OCT images.
abstract: The optical coherence tomography (OCT) evaluation of the stent anatomy requires the inspection of sequential cross section (CS). However stent coils cannot be appreciated in the conventional format as the OCT CS simply display stent struts, that are poorly representative of the stent architecture. The aim of the present study was to validate a new software (Carpet View), which unfolds the stented segment, reconstructing it as an open structure and displaying the stent meshwork. 21 patients were studied with frequency domain OCT after the deployment of different stents: seven bio-absorbable scaffolds (Dream), seven bare metal stent (Vision/Multilink8), seven drug eluting stent (Cre8). Conventional CS reconstructions were post-processed with the Carpet View software and analyzed by the same reader twice (intra-observer variability) and by two different readers (inter-observer variability). A small average difference in the number of all struts was obtained with the two methods (conventional vs carpet view reconstruction). Using the carpet view, high intra-observer and inter-observer correlations were found for the number of struts obtained in each coil. The Pearson correlation values were 0.98 (p = 0.0001) and 0.96 (p = 0.0001) respectively. The same number of coils was found when analyses were repeated by the same reader or by a different reader whilst mild differences in the count of stent junctions were reported. The Carpet View can be used to address the stent geometry with high reproducibility. This approach enables the matching of the same stent portion during serial time points and promises to improve the stent assessment.
authors.affiliation: Centro per la Lotta contro l'Infarto - Fondazione Onlus, Rome, Italy.
authors.forename: Alex
authors.initials: A
authors.lastname: Gabriele
authors.forename: Valeria
authors.initials: V
authors.lastname: Marco
authors.forename: Laura
authors.initials: L
authors.lastname: Gatto
authors.forename: Giulia
authors.initials: G
authors.lastname: Paoletti
authors.forename: Luca
authors.initials: L
authors.lastname: Di Vito
authors.forename: Fausto
authors.initials: F
authors.lastname: Castriota
authors.forename: Enrico
authors.initials: E
authors.lastname: Romagnoli
authors.forename: Andrea
authors.initials: A
authors.lastname: Ricciardi
authors.forename: Francesco
authors.initials: F
authors.lastname: Prati
mesh_terms: D003324:Coronary Artery Disease / Q000473:pathology / Q000628:therapy*; D003331:Coronary Vessels / Q000473:pathology*; D054855:Drug-Eluting Stents; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008670:Metals; D015588:Observer Variation; D062645:Percutaneous Coronary Intervention / Q000295:instrumentation; D011237:Predictive Value of Tests; D011474:Prosthesis Design; D015203:Reproducibility of Results; D012986:Software Validation; D015607:Stents; D041623:Tomography, Optical Coherence / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D008670:Metals