title: [A single-center retrospective study on the intraluminal implantation of inferior vena cava filter for the lower extremity trauma patients with deep venous thrombosis].
abstract: OBJECTIVE
  To evaluate the application of inferior vena cava filter (IVCF) in prevention of peri-operative pulmonary embolism (PE) in lower limb bone fracture patients with deep venous thrombosis (DVT).
  
  
  METHODS
  From January 2003 to December 2012, 2 248 cases of lower limb and pelvic fractures with DVT were retrospectively analyzed. Before the procedure of IVCF implantation began, January 2003 to December 2007, there were 1 052 cases of acute trauma patients with DVT were classified as the group of early none-IVCF. The IVCF implantation was began since January 2008. From that time to December 2012, 712 cases of bone fractures with DVT received filter implantation, which were classified as IVCF group. The other 484 patients who had not undergone filter deployment were divided as group of late none-IVCF. The baseline conditions of the three groups were significantly different in addition to the ages between group of early none-IVCF and IVCF group. The incidences of PE and mortality of PE in each group were recorded and analyzed by χ(2) test.
  
  
  RESULTS
  There were totally 31 cases of symptomatic PE, among which 12 cases died. Totally 712 filters were deployed successfully without any major complications. The incidences of symptomatic PE were 0.14% (1/712), 2.19% (23/1 052) and 1.45% (7/484) in IVCF group, group of early none-IVCF and group of late none-IVCF, respectively. The mortality of PE were 0 (0/712), 0.86% (9/1 052) and 0.62% (3/484) in these groups. The incidence of symptomatic PE in IVCF group was significantly different from that in the group of early and late none-IVCF (χ(2) = 11.762, P = 0.001; χ(2) = 7.395, P = 0.007, respectively). The mortality of IVCF group was also significantly lower compared with the other two groups (χ(2) = 6.122, P = 0.013; χ(2) = 4.424, P = 0.035, respectively).
  
  
  CONCLUSIONS
  IVCF implantation effectively prevents symptomatic and fatal PE of patients of lower limb and pelvic fractures with DVT in the peri-operative period.
authors.affiliation: Department of Vascular Surgery, Shanghai Sixth Affiliated People's Hospital of Shanghai Jiaotong University, Shanghai 200233, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Pan
authors.affiliation: Email: junnzhao@126.com.
authors.forename: Jun
authors.initials: J
authors.lastname: Zhao
authors.forename: Yuqiang
authors.initials: Y
authors.lastname: Sun
authors.forename: Yunfeng
authors.initials: Y
authors.lastname: Chen
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Zhou
authors.forename: Ronggang
authors.initials: R
authors.lastname: Xia
authors.forename: Mingzhe
authors.initials: M
authors.lastname: Shao
authors.forename: Jian
authors.initials: J
authors.lastname: Zhang
authors.forename: Haisheng
authors.initials: H
authors.lastname: Wu
authors.forename: Jiacai
authors.initials: J
authors.lastname: Mei
authors.forename: Mingjie
authors.initials: M
authors.lastname: Tang
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
authors.forename: Jianzhong
authors.initials: J
authors.lastname: Di
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007869:Leg Injuries / Q000150:complications*; D035002:Lower Extremity; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000209:etiology / Q000517:prevention & control*; D012189:Retrospective Studies; D016306:Vena Cava Filters; D020246:Venous Thrombosis / Q000150:complications*