title: Total skin electron beam (TSEB) therapy in pediatric patients: A review of the literature.
abstract: OBJECTIVE
  A literature review was undertaken to identify current TSEB therapy in pediatric patients.
  
  
  BACKGROUND
  Total skin electron beam (TSEB) therapy is a method of irradiation with low energy electron beam dedicated to patients who have superficial skin lesions all over their body. Such skin malignancies are sparse among adults and even more uncommon with pediatric population.
  
  
  METHODS
  In this study, all reported case reports were summed up with a special emphasis on techniques used, doses prescribed and special shielding of critical organs. Moreover, potential problems that were encountered during TSEB irradiation of very young patients were depicted.
  
  
  RESULTS
  The literature has described only seven case reports of children undergoing TSEB therapy. Most of them were infants; however, two adolescents were also treated. For all infants, general anesthesia was provided to allow safe and accurate TSEB irradiation. The prescribed dose varied from 16 Gy to 28 Gy depending on the irradiation schedule and patient condition. Usually, boost fields were applied to the scalp and perineum. Typical shields for fingernails, toenails and lenses were usually used.
  
  
  CONCLUSIONS
  This paper revealed that TSEB therapy may be considered as a palliative treatment for pediatric patients with leukemia cutis. However, its role is still unclear and should be further investigated.
authors.affiliation: Department of Medical Physics, Greater Poland Cancer Centre, Poznan, Poland.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Skórska
keywords: Leukemia cutis; Pediatric total skin electron beam therapy; TSEB