title: Liposomes versus metallic nanostructures: differences in the process of knowledge translation in cancer.
abstract: This research maps the knowledge translation process for two different types of nanotechnologies applied to cancer: liposomes and metallic nanostructures (MNs). We performed a structural analysis of citation networks and text mining supported in controlled vocabularies. In the case of liposomes, our results identify subnetworks (invisible colleges) associated with different therapeutic strategies: nanopharmacology, hyperthermia, and gene therapy. Only in the pharmacological strategy was an organized knowledge translation process identified, which, however, is monopolized by the liposomal doxorubicins. In the case of MNs, subnetworks are not differentiated by the type of therapeutic strategy, and the content of the documents is still basic research. Research on MNs is highly focused on developing a combination of molecular imaging and photothermal therapy.
authors.affiliation: Faculty of Medicine of the National Autonomous University of Mexico, Mexico City, Mexico.
authors.forename: David
authors.initials: D
authors.lastname: Fajardo-Ortiz
authors.affiliation: Faculty of Medicine of the National Autonomous University of Mexico, Mexico City, Mexico.
authors.forename: Luis
authors.initials: L
authors.lastname: Duran
authors.affiliation: Faculty of Medicine of the National Autonomous University of Mexico, Mexico City, Mexico.
authors.forename: Laura
authors.initials: L
authors.lastname: Moreno
authors.affiliation: El Colegio de la Frontera Sur, San Cristobal de las Casas, Mexico.
authors.forename: Héctor
authors.initials: H
authors.lastname: Ochoa
authors.affiliation: Faculty of Medicine of the National Autonomous University of Mexico, Mexico City, Mexico ; Molecular Material Department, Applied Physics and Advanced Technology Center, National Autonomous University of Mexico, Juriquilla, Mexico ; Advanced Technology Center, CIATEQ, Queretaro, Mexico.
authors.forename: Víctor M
authors.initials: VM
authors.lastname: Castaño
mesh_terms: D038622:Internationality; D008081:Liposomes / Q000627:therapeutic use*; D053768:Metal Nanoparticles / Q000627:therapeutic use*; D036103:Nanotechnology / Q000706:statistics & numerical data*; D010506:Periodicals as Topic / Q000706:statistics & numerical data*; D057170:Translational Research, Biomedical / Q000706:statistics & numerical data*
chemical_list: D008081:Liposomes
keywords: basic research; citation network analysis; clinics; health care; nanotechnology