title: Increased density of Demodex folliculorum mites in pregnancies with gestational diabetes.
abstract: OBJECTIVE
  To investigate the presence of Demodex in patients with gestational diabetes and the impact of glucose regulation on Demodex density in gestational diabetes.
  
  
  METHODS
  The study population consisted of 33 patients with gestational diabetes and 30 pregnant women without gestational diabetes (control group). The age, parity, gestational age, and BMI of the study group were recorded and the patients were divided into 2 groups, i.e. those with regulated and unregulated glucose levels, according to their postprandial 1st- and 2nd-hour glucose values. A standardized skin surface biopsy method was used to determine if patients had Demodex folliculorum infestation (>5 mites/cm(2) of skin).
  
  
  RESULTS
  Patients with gestational diabetes had a statistically significantly higher Demodex density compared to the control group (24.2 vs. 3.3%; p < 0.001). Furthermore, a significantly higher proportion of gestational diabetes patients with unregulated glucose levels had a higher Demodex density compared to those in the regulated subgroup (6/19 vs. 2/14; p = 0.001).
  
  
  CONCLUSIONS
  Our study revealed that the Demodex density was increased in gestational diabetes patients. Further, poor glucose regulation could be the mechanism responsible for the increased Demodex density in gestational diabetes patients with unregulated glucose levels compared to those with regulated glucose levels.
authors.affiliation: Department of Obstetrics and Gynecology, Mustafa Kemal University Medical School, Hatay, Turkey.
authors.forename: Raziye
authors.initials: R
authors.lastname: Keskin Kurt
authors.forename: Ozlem
authors.initials: O
authors.lastname: Aycan Kaya
authors.forename: Atilla
authors.initials: A
authors.lastname: Karateke
authors.forename: Dilek Benk
authors.initials: DB
authors.lastname: Silfeler
authors.forename: Oya
authors.initials: O
authors.lastname: Soylu Karapınar
authors.forename: Ayse Neslin
authors.initials: AN
authors.lastname: Akkoca
authors.forename: Ali Ulvi
authors.initials: AU
authors.lastname: Hakverdi
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000818:Animals; D001786:Blood Glucose; D015992:Body Mass Index; D016640:Diabetes, Gestational / Q000097:blood / Q000453:epidemiology*; D005140:Eyelashes / Q000469:parasitology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D008924:Mite Infestations / Q000097:blood / Q000453:epidemiology*; D010298:Parity; D011247:Pregnancy; D012867:Skin / Q000469:parasitology*; D055815:Young Adult
chemical_list: D001786:Blood Glucose