title: [Advance in studies on long-circulating tumor targeted compound preparations].
abstract: Tumor has long been a hard-nut problem in the world medical field. The effect of the conventional drugs is very limited because of the intervention of multiple micro-environmental factors during the occurrence and progression of tumors. With the characteristics of high efficiency, low toxicity and multi-targets synergistic effect, the long-circulating tumor targeted compound preparations show its unique advantages in improving tumor microenvironment and enhancing the therapeutic effect of treatment, thus it has gradually become a hotspot of studies both at home and abroad. Through consulting a great number of professional literatures at home and abroad in recent years, the authors summarized the current studies in vitro and in vive on long-circulating tumor targeted compound preparations in different carriers, in the expectation of providing new ideas and methods for the development of long-circulating tumor targeted compound preparations.
authors.forename: Qiu-Ping
authors.initials: QP
authors.lastname: Li
authors.forename: Xiao-Man
authors.initials: XM
authors.lastname: Liu
authors.forename: Jun-Dong
authors.initials: JD
authors.lastname: Dai
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000097:blood* / Q000737:chemistry* / Q000627:therapeutic use; D004339:Drug Compounding / Q000379:methods*; D006801:Humans; D058990:Molecular Targeted Therapy / Q000379:methods*; D009369:Neoplasms / Q000097:blood* / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents