title: Venous thromboembolism and antithrombotic therapy in pregnancy.
abstract: OBJECTIVE
  To present an approach, based on current evidence, for the diagnosis, treatment, and thromboprophylaxis of venous thromboembolism in pregnancy and postpartum.
  
  
  METHODS
  Published literature was retrieved through searches of PubMed, Medline, CINAHL, and The Cochrane Library from November 2011 to July 2013 using appropriate controlled vocabulary (e.g. pregnancy, venous thromboembolism, deep vein thrombosis, pulmonary embolism, pulmonary thrombosis) and key words (e.g., maternal morbidity, pregnancy complications, thromboprophylaxis, antithrombotic therapy). Results were restricted to systematic reviews, randomized control trials/controlled clinical trials, and observational studies published in English or French. There were no date restrictions. Grey (unpublished) literature was identified through searching the websites of clinical practice guideline collections, clinical trial registries, and national and international medical specialty societies.
  
  
  METHODS
  The quality of evidence in this document was rated using the criteria described in the Report of the Canadian Task Force on Preventative Health Care (Table 1).
authors.affiliation: Vancouver BC.
authors.forename: Wee-Shian
authors.initials: WS
authors.lastname: Chan
authors.affiliation: Montreal QC.
authors.forename: Evelyne
authors.initials: E
authors.lastname: Rey
authors.affiliation: Vancouver BC.
authors.forename: Nancy E
authors.initials: NE
authors.lastname: Kent
authors.affiliation: Vancouver BC.
authors.forename: Wee-Shian
authors.initials: WS
authors.lastname: Chan
authors.affiliation: Vancouver BC.
authors.forename: Nancy E
authors.initials: NE
authors.lastname: Kent
authors.affiliation: Montreal QC.
authors.forename: Evelyne
authors.initials: E
authors.lastname: Rey
authors.affiliation: Edmonton AB.
authors.forename: Thomas
authors.initials: T
authors.lastname: Corbett
authors.affiliation: Montreal QC.
authors.forename: Michèle
authors.initials: M
authors.lastname: David
authors.affiliation: Vancouver BC.
authors.forename: M Joanne
authors.initials: MJ
authors.lastname: Douglas
authors.affiliation: Calgary AB.
authors.forename: Paul S
authors.initials: PS
authors.lastname: Gibson
authors.affiliation: Vancouver BC.
authors.forename: Laura
authors.initials: L
authors.lastname: Magee
authors.affiliation: Ottawa ON.
authors.forename: Marc
authors.initials: M
authors.lastname: Rodger
authors.affiliation: Victoria BC.
authors.forename: Reginald E
authors.initials: RE
authors.lastname: Smith
mesh_terms: D000208:Acute Disease; D000465:Algorithms; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis* / Q000628:therapy*; D054556:Venous Thromboembolism / Q000175:diagnosis* / Q000628:therapy*
chemical_list: D005343:Fibrinolytic Agents
keywords: adverse pregnancy outcomes; assisted reproductive technology; deep vein thrombosis; heparin; neuraxial analgesia; pregnancy or puerperal complications; pulmonary embolism; thromboprophylaxis; venous thromboembolism