title: [Comparison the effects of prilocaine and the addition of dexketoprofen and dexamethasone to prilocaine for intravenous regional anesthesia].
abstract: OBJECTIVE
  The aim of this study was to compare the anesthetic and analgesic effects of prilocaine alone, prilocaine added dexketoprofen and dexamethasone during intravenous regional anesthesia (IVRA).
  
  
  METHODS
  Forty five patients undergoing forearm or hand surgery were randomly assigned to one of three groups to receive (Group P) 3 mg/kg 0.5% prilocaine; (Group PDK) 3 mg/kg 0.5% prilocaine plus 50 mg dexketoprofen; (Group PDM) 3 mg/kg 0.5% prilocaine plus 8 mg dexamethasone in total 40 ml volume for IVRA. The onset and duration of sensory and motor blocks, hemodynamic datas, duration of analgesia and tourniquet, time to first analgesic requirement, visual analog scale (VAS), total analgesic consumption in 24 hours and patient satisfaction score were assessed and recorded.
  
  
  RESULTS
  Time to onset of sensory block was found to be longer in Group P (p<0.05), though no significance was found according to sensory block recovery times amoung groups. Time to onset of motor block was found to be longer and recovery time of motor block was found to be shorter in Group P (p<0.05). Time to first analgesic requirement was found to be longer in Group PDK,and was found to be high in Group PDM than Group PDK(p<0.05). The VAS scores was found to be high and patient satisfaction scale was found to be low in Group P (p<0.05).
  
  
  CONCLUSIONS
  The addition of dexketoprofen and dexamethasone to prilocaine during IVRA improves the quality of both anesthesia and analgesia moreover dexketoprofen provides beter postoperative analgesia during the first 24 hour after surgery.
authors.affiliation: Department of Anesthesiology and Reanimation, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey. borazanh@hotmail.com.
authors.forename: Hale
authors.initials: H
authors.lastname: Borazan
authors.affiliation: Department of Anesthesiology and Reanimation, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey.
authors.forename: Osman
authors.initials: O
authors.lastname: Sahin
authors.affiliation: Department of Anesthesiology and Reanimation, Meram Training and Research Hospital, Konya, Turkey.
authors.forename: Mehmet Selçuk
authors.initials: MS
authors.lastname: Uluer
authors.affiliation: Department of Anesthesiology and Reanimation, Meram Training and Research Hospital, Konya, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Keçecioğlu
authors.affiliation: Department of Anesthesiology and Reanimation, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey.
authors.forename: Tuba Berra
authors.initials: TB
authors.lastname: Sarıtaş
authors.affiliation: Department of Anesthesiology and Reanimation, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey.
authors.forename: Seref
authors.initials: S
authors.lastname: Otelcioğlu
mesh_terms: D000293:Adolescent; D000328:Adult; D019162:Anesthetics, Combined; D018686:Anesthetics, Intravenous / Q000008:administration & dosage / Q000627:therapeutic use*; D003907:Dexamethasone / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D005542:Forearm / Q000601:surgery; D006225:Hand / Q000601:surgery; D006801:Humans; D007262:Infusions, Intravenous; D007660:Ketoprofen / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D019637:Orthopedic Procedures; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D011318:Prilocaine / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome; D014325:Tromethamine / Q000008:administration & dosage / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D019162:Anesthetics, Combined; D018686:Anesthetics, Intravenous; D014325:Tromethamine; D011318:Prilocaine; D003907:Dexamethasone; D007660:Ketoprofen; C118296:dexketoprofen trometamol