title: Comparative analysis of conjugated alkynyl chromophore-triazacyclononane ligands for sensitized emission of europium and terbium.
abstract: A series of europium and terbium complexes based on a functionalized triazacyclononane carboxylate or phosphinate macrocyclic ligand is described. The influence of the anionic group, that is, carboxylate, methylphosphinate, or phenylphosphinate, on the photophysical properties was studied and rationalized on the basis of DFT calculated structures. The nature, number, and position of electron-donating or electron-withdrawing aryl substituents were varied systematically within the same phenylethynyl scaffold in order to optimize the brightness of the corresponding europium complexes and investigate their two-photon absorption properties. Finally, the europium complexes were examined in cell-imaging applications, and selected terbium complexes were studied as potential oxygen sensors.
authors.affiliation: Cisbio Bioassays, Parc Marcel Boiteux, BP 84175, 30200 Codolet (France).
authors.forename: Marine
authors.initials: M
authors.lastname: Soulié
authors.forename: Frédéric
authors.initials: F
authors.lastname: Latzko
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Bourrier
authors.forename: Virginie
authors.initials: V
authors.lastname: Placide
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Butler
authors.forename: Robert
authors.initials: R
authors.lastname: Pal
authors.forename: James W
authors.initials: JW
authors.lastname: Walton
authors.forename: Patrice L
authors.initials: PL
authors.lastname: Baldeck
authors.forename: Boris
authors.initials: B
authors.lastname: Le Guennic
authors.forename: Chantal
authors.initials: C
authors.lastname: Andraud
authors.forename: Jurriaan M
authors.initials: JM
authors.lastname: Zwier
authors.forename: Laurent
authors.initials: L
authors.lastname: Lamarque
authors.forename: David
authors.initials: D
authors.lastname: Parker
authors.forename: Olivier
authors.initials: O
authors.lastname: Maury
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001372:Aza Compounds / Q000737:chemistry*; D005063:Europium / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010880:Piperidines / Q000737:chemistry*; D013725:Terbium / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001372:Aza Compounds; D008024:Ligands; D009942:Organometallic Compounds; D010880:Piperidines; C482777:triazacyclononane; D013725:Terbium; D005063:Europium
keywords: imaging agents; lanthanides; macrocyclic ligands; photophysics; sensors