title: Cardiac structural abnormalities associated with IgG4-related coronary periarteritis and inflammation revealed by multimodality imaging.
abstract: A man presented with shortness of breath, and a globular heart was seen on a chest radiograph. An echocardiogram showed masses at the atrioventricular grooves. Computed tomography (CT) coronary angiography and fluorine-18 ((18)F) fluorodeoxyglucose positron emission tomography (FDG-PET)/CT confirmed coronary aneurysms with hypermetabolic perivascular masses at the coronary arteries and right internal iliac artery. Histologic features were highly suspicious for IgG4-related disease (IgG4-RD). IgG4-RD is a recently recognized fibroinflammatory condition, and FDG-PET/CT can provide information about the disease pattern, which may suggest IgG4-RD, as well as the optimal biopsy site.
authors.affiliation: Department of Nuclear Medicine and PET, Singapore General Hospital, Singapore, Singapore. Electronic address: aaron.arrowt@gmail.com.
authors.forename: Aaron Kian-Ti
authors.initials: AK
authors.lastname: Tong
authors.affiliation: Department of Pathology, Singapore General Hospital, Singapore, Singapore.
authors.forename: Soo-Yong
authors.initials: SY
authors.lastname: Tan
authors.affiliation: Department of Cardiology, National Heart Centre, Singapore, Singapore.
authors.forename: Yun-Yun
authors.initials: YY
authors.lastname: Go
authors.affiliation: Department of Nuclear Medicine and PET, Singapore General Hospital, Singapore, Singapore.
authors.forename: Winnie Wing-Chuen
authors.initials: WW
authors.lastname: Lam
mesh_terms: D001167:Arteritis / Q000175:diagnosis*; D001327:Autoimmune Diseases / Q000175:diagnosis*; D003323:Coronary Aneurysm / Q000175:diagnosis; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000473:pathology*; D004452:Echocardiography; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D007074:Immunoglobulin G; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18