title: Total laparoscopic radical trachelectomy in the treatment of early-stage cervical cancer: review of technique and outcomes.
abstract: OBJECTIVE
  Fertility preservation in early-stage cervical cancer by total laparoscopic radical trachelectomy (TLRT) is gaining acceptance as more cases are published in the literature. The objective is to review all the literatures regarding TLRT especially over the last 12 months and to describe the technique, the operative outcomes, the oncologic outcomes and the obstetric outcomes of this procedure.
  
  
  RESULTS
  As the number of cases reported in the literature increases, the effectiveness of TLRT for treating early-stage cervical cancer continues to gain support. Under the enhanced vision of the laparoscopy, it is easy to preserve the ascending branches of the uterine arteries and to divide the ligaments surrounding the cervix and vagina. Since TLRT was first reported, about 140 cases of TLRT have been reported. The tumour recurrence rate is 2.9%. Fifty-nine out of 140 patients attempted to conceive after TLRT, and forty-six patients succeeded. There were 17 miscarriages, 14 preterm births and 11 term births.
  
  
  CONCLUSIONS
  TLRT appears well tolerated and effective when performed in centres with appropriate experience of laparoscopic techniques. Continued research and clinical trials are needed to further elucidate the equivalence or superiority of TLRT to conventional methods in terms of obstetric outcome and patients' quality of life.
authors.affiliation: Department of Obstetrics and Gynecology, Chao-yang Hospital, Capital Medical University, Beijing, People's Republic of China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Lu
authors.forename: Chongdong
authors.initials: C
authors.lastname: Liu
authors.forename: Zhenyu
authors.initials: Z
authors.lastname: Zhang
mesh_terms: D002584:Cervix Uteri / Q000473:pathology / Q000601:surgery*; D005260:Female; D059247:Fertility Preservation / Q000379:methods; D013509:Gynecologic Surgical Procedures / Q000379:methods; D006801:Humans; D010535:Laparoscopy; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D009367:Neoplasm Staging; D011247:Pregnancy; D018873:Pregnancy Rate; D011788:Quality of Life; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*