title: Preliminary thermoluminescence and optically stimulated luminescence investigation of commercial pharmaceutical preparations towards the drug sterilization dosimetry.
abstract: Drug sterilization with ionizing radiation is a well-established technology and is gaining ground the last decades due to its numerous advantages. Identification of irradiated drugs would be interesting and, in this respect, the present work aims, for the first time to the authors' best knowledge, to explore whether OSL and TL can be employed as methods for post-sterilization dosimetry on commercial drugs, i.e., as tools for the detection of irradiated drugs. Five widely used drugs, i.e., Daktarin(®), Aspirin(®), Panadol(®), Brufen(®) and Procef(®), are used for this purpose. Preliminary findings are very promising towards the post-sterilization dosimetry and the use of commercial drugs for normal and/or accidental dosimetry.
authors.affiliation: Nuclear Physics Laboratory, Physics Department, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece; Department of Archaeometry and Physicochemical Measurements, R.C. 'Athena', PO Box 159, Kimmeria University Campus, 67100 Xanthi, Greece. Electronic address: nikkazak@ceti.gr.
authors.forename: Nikolaos A
authors.initials: NA
authors.lastname: Kazakis
authors.affiliation: Department of Archaeometry and Physicochemical Measurements, R.C. 'Athena', PO Box 159, Kimmeria University Campus, 67100 Xanthi, Greece.
authors.forename: Nestor C
authors.initials: NC
authors.lastname: Tsirliganis
authors.affiliation: Nuclear Physics Laboratory, Physics Department, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
authors.forename: George
authors.initials: G
authors.lastname: Kitis
mesh_terms: D062791:Optically Stimulated Luminescence Dosimetry / Q000379:methods* / Q000592:standards; D004364:Pharmaceutical Preparations / Q000032:analysis* / Q000528:radiation effects*; D013242:Sterilization / Q000379:methods*; D013819:Thermoluminescent Dosimetry / Q000379:methods* / Q000592:standards
chemical_list: D004364:Pharmaceutical Preparations
keywords: Aspirin; Drugs; Infrared stimulated luminescence; Optically stimulated luminescence; Sterilization; Thermoluminescence