title: Surface osteosarcomas: Diagnosis, treatment and outcome.
abstract: Surface osteosarcomas are a rare form of osteosarcomas accounting for around 3-6% of all osteosarcomas. Three major groups of surface osteosarcomas are parosteal, periosteal and the high grade surface osteosarcomas. Of these, the parosteal osteosarcoma is the most common. Parosteal and periosteal osteosarcomas are distinct clinical entities and it is important to identify the clinicoradiological differences between the two types. Surface osteosarcomas occur at a later age as compared to conventional osteosarcomas. The classical site is the lower end of the femur followed by the upper end of the tibia and upper end of humerus, in that order. The periosteal variant affects the tibia more commonly than the parosteal variety. Neo-adjuvant chemotherapy is the standard of care for high grade surface osteosarcomas. Parosteal osteosarcomas, being low grade lesions, can be treated by upfront wide excision without adjuvant systemic therapy. Controversy prevails over the need for chemotherapy in periosteal osteosarcomas, which are intermediate grade lesions.
authors.affiliation: Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Venkatesan Sampath
authors.initials: VS
authors.lastname: Kumar
authors.affiliation: Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Nilesh
authors.initials: N
authors.lastname: Barwar
authors.affiliation: Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Shah Alam
authors.initials: SA
authors.lastname: Khan
keywords: High grade; parosteal; periosteal; surface osteosarcoma