title: Report on the international colloquium on cardio-oncology (rome, 12-14 march 2014).
abstract: Cardio-oncology is a relatively new discipline that focuses on the cardiovascular sequelae of anti-tumour drugs. As any other young adolescent discipline, cardio-oncology struggles to define its scientific boundaries and to identify best standards of care for cancer patients or survivors at risk of cardiovascular events. The International Colloquium on Cardio-Oncology was held in Rome, Italy, 12-14 March 2014, with the aim of illuminating controversial issues and unmet needs in modern cardio-oncology. This colloquium embraced contributions from different kind of disciplines (oncology and cardiology but also paediatrics, geriatrics, genetics, and translational research); in fact, cardio-oncology goes way beyond the merging of cardiology with oncology. Moreover, the colloquium programme did not review cardiovascular toxicity from one drug or the other, rather it looked at patients as we see them in their fight against cancer and eventually returning to everyday life. This represents the melting pot in which anti-cancer therapies, genetic backgrounds, and risk factors conspire in producing cardiovascular sequelae, and this calls for screening programmes and well-designed platforms of collaboration between one key professional figure and another. The International Colloquium on Cardio-Oncology was promoted by the Menarini International Foundation and co-chaired by Giorgio Minotti (Rome), Joseph R Carver (Philadelphia, Pennsylvania, United States), and Steven E Lipshultz (Detroit, Michigan, United States). The programme was split into five sessions of broad investigational and clinical relevance (what is cardiotoxicity?, cardiotoxicity in children, adolescents, and young adults, cardiotoxicity in adults, cardiotoxicity in special populations, and the future of cardio-oncology). Here, the colloquium chairs and all the session chairs briefly summarised what was said at the colloquium. Topics and controversies were reported on behalf of all members of the working group of the International Colloquium on Cardio-Oncology.
authors.affiliation: The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Ewer
authors.affiliation: San Raffaele Hospital, Milan 20132, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Gianni
authors.affiliation: Federico II University School of Medicine, Naples 80131, Italy.
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Pane
authors.affiliation: European Institute of Oncology, Milan 20141, Italy.
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Sandri
authors.affiliation: University of Zurich, Zurich 8006, Switzerland.
authors.forename: Rudolf K
authors.initials: RK
authors.lastname: Steiner
authors.affiliation: University of Mainz, Mainz 55099, Germany.
authors.forename: Leszek
authors.initials: L
authors.lastname: Wojnowski
authors.affiliation: The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
authors.forename: Edward T
authors.initials: ET
authors.lastname: Yeh
authors.affiliation: University of Pennsylvania and Abramson Cancer Center, 1600 Penn Tower, 3400 Spruce St, Philadelphia, PA 19104, USA.
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Carver
authors.affiliation: Wayne State University and Children's Hospital of Michigan, 3901 Beaubien Blvd, Detroit, MI 48201, USA.
authors.forename: Steven E
authors.initials: SE
authors.lastname: Lipshultz
authors.affiliation: University Campus Bio-Medico, Via Alvaro del Portillo 21, Rome 00128, Italy.
authors.forename: Giorgio
authors.initials: G
authors.lastname: Minotti
authors.affiliation: Working Group of the International Colloquium on Cardio-Oncology (St Jude Children's Research Hospital, Memphis, TN 38105, USA).
authors.forename: Gregory T
authors.initials: GT
authors.lastname: Armstrong
authors.affiliation: Working Group of the International Colloquium on Cardio-Oncology (European Institute of Oncology, Milan 20141, Italy).
authors.forename: Daniela
authors.initials: D
authors.lastname: Cardinale
authors.affiliation: Working Group of the International Colloquium on Cardio-Oncology (Harvard Medical School, Boston, MA 02115, USA).
authors.forename: Steven D
authors.initials: SD
authors.lastname: Colan
authors.affiliation: Working Group of the International Colloquium on Cardio-Oncology (University of Oxford, Oxford OX3 7LF, UK).
authors.forename: Sarah C
authors.initials: SC
authors.lastname: Darby
authors.affiliation: Working Group of the International Colloquium on Cardio-Oncology (Vanderbilt University School of Medicine, Nashville 37232, TN, USA).
authors.forename: Thomas L
authors.initials: TL
authors.lastname: Force
authors.affiliation: Working Group of the International Colloquium on Cardio-Oncology (Emma Children's Hospital-Academic Medical Center, Amsterdam 1100 DD, The Netherlands).
authors.forename: Leontien Cm
authors.initials: LC
authors.lastname: Kremer
authors.affiliation: Working Group of the International Colloquium on Cardio-Oncology (Vanderbilt University School of Medicine, Nashville 37232, TN, USA).
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Lenihan
authors.affiliation: Working Group of the International Colloquium on Cardio-Oncology (Dana-Farber Cancer Institute, Boston, MA 02215, USA).
authors.forename: Stephen E
authors.initials: SE
authors.lastname: Sallan
authors.affiliation: Working Group of the International Colloquium on Cardio-Oncology (Vanderbilt University School of Medicine, Nashville 37232, TN, USA).
authors.forename: Douglas B
authors.initials: DB
authors.lastname: Sawyer
authors.affiliation: Working Group of the International Colloquium on Cardio-Oncology (Bern University Hospital, Bern 3012, Switzerland).
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Suter
authors.affiliation: Working Group of the International Colloquium on Cardio-Oncology (Washington Cancer Institute, Washington, DC 20010, USA).
authors.forename: Sandra M
authors.initials: SM
authors.lastname: Swain
authors.affiliation: Working Group of the International Colloquium on Cardio-Oncology (Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands).
authors.forename: Flora E
authors.initials: FE
authors.lastname: van Leeuwen
keywords: antitumor therapies; cardio-oncology; cardiovascular sequelae; patients; survivors