title: [Dynamics of inflammatory mediators and indices of antiendotoxic immunity in children with purulent-destructive pneumonia].
abstract: There were examined 220 children, in whom purulent-destructive pneumonia (PDP) was diagnosed. Level of anti-inflammatory mediators and indices of the antiendotoxine immunity was determined in the blood serum, using immunoassay analysis, after admittance to hospital. There was established, that in PDP in children the concentration of anti-inflammatory mediators interleucines (IL--1 beta, IL-6) is enhanced, as well as of the tumor necrosis factor-- alpha (TNF-alpha), C-reactive protein (CRP), while titre of antibodies to endotoxine class G lowers, and the level of lipopolisaccharid-binded protein (LBP) and soluble form of CD14 receptor (sCD14) is raised, not depending from the patient state severity.
authors.forename: L F
authors.initials: LF
authors.lastname: Pritulo
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Bisiuk
mesh_terms: D000293:Adolescent; D002097:C-Reactive Protein / Q000032:analysis*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D016207:Cytokines / Q000097:blood*; D003627:Data Interpretation, Statistical; D006801:Humans; D056724:Immunity, Humoral; D007223:Infant; D053583:Interleukin-1beta / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D007700:Kinetics; D009336:Necrosis; D018410:Pneumonia, Bacterial / Q000097:blood / Q000276:immunology* / Q000473:pathology*; D012720:Severity of Illness Index; D013492:Suppuration; D014409:Tumor Necrosis Factor-alpha / Q000097:blood
chemical_list: D016207:Cytokines; C508585:IL1B protein, human; C508600:IL6 protein, human; D053583:Interleukin-1beta; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha; D002097:C-Reactive Protein