title: Cytomegalovirus-related hemorrhagic cystitis in an immunocompetent child.
abstract: Cytomegalovirus (CMV) infections are mostly seen in immunocompromised patients. However, unusual manifestations or complications of acquired CMV infections in immunocompetent patients are rarely reported. CMV-related hemorrhagic cystitis is extremely rare but should be considered even in immunocompetent patients. We present a case of a 3-year-old immunocompetent boy with intermittent, terminal gross hematuria lasting for 1 month. There was no history of genitourinary trauma or stone disease. Urine analysis revealed hematuria with eumorphic red blood cells and no proteinuria. Urine culture was negative. Ultrasonography showed increased bladder wall thickness and irregularity at inferior of bladder. Cystoscopy revealed hyperemia and edema. Histopathological examination was consistent with CMV infection, viral DNA by polymerase chain reaction in peripheral blood and urine were positive. Clinical, laboratory, and imaging features pointed towards hemorrhagic cystitis due to CMV. He was followed-up with no treatment. After 1 month, repeated investigations showed complete resolution of finding. This is a rare description of an immunocompetent child with CMV-induced cystitis.
authors.affiliation: Department of Pediatric Nephrology and Rheumatology, Ankara Child Health, Hematology, Oncology Education and Research Hospital , Ankara , Turkey .
authors.forename: Aysel
authors.initials: A
authors.lastname: Taktak
authors.forename: Banu
authors.initials: B
authors.lastname: Acar
authors.forename: Gökçe
authors.initials: G
authors.lastname: Gür
authors.forename: Tuğrul
authors.initials: T
authors.lastname: Tiryaki
authors.forename: Esra
authors.initials: E
authors.lastname: Karakuş
authors.forename: F Şemsa
authors.initials: FŞ
authors.lastname: Çaycı
authors.forename: Nermin
authors.initials: N
authors.lastname: Uncu
authors.forename: Nilgün
authors.initials: N
authors.lastname: Çakar
mesh_terms: D002675:Child, Preschool; D003556:Cystitis / Q000150:complications / Q000821:virology*; D003586:Cytomegalovirus Infections / Q000150:complications*; D006417:Hematuria / Q000821:virology*; D006801:Humans; D007121:Immunocompetence; D008297:Male
keywords: Child; cytomegalovirus; hemorrhagic cystitis; immunocompetent