title: A simple and efficient synthesis of fused morpholine pyrrolidines/piperdines with potential insecticidal activities.
abstract: A simple and efficient synthesis of fused morpholine pyrrolidine/piperdine core structures was accomplished via a Petasis-borono Mannich reaction of cyclic amino alcohols, glyoxal and arylboronic acids with moderate to good yields. The bioassay data showed that the synthesized compounds displayed selective insecticidal activities against armyworm and root-knot nematode.
authors.affiliation: Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai, 200237, People's Republic of China.
authors.forename: Jiayi
authors.initials: J
authors.lastname: Wang
authors.forename: Beiling
authors.initials: B
authors.lastname: Xu
authors.forename: Shanyu
authors.initials: S
authors.lastname: Si
authors.forename: Hui
authors.initials: H
authors.lastname: Li
authors.forename: Gonghua
authors.initials: G
authors.lastname: Song
mesh_terms: D000818:Animals; D007306:Insecticides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D015394:Molecular Structure; D009025:Morpholines / Q000737:chemistry*; D009348:Nematoda / Q000187:drug effects; D011759:Pyrrolidines / Q000737:chemistry*
chemical_list: D007306:Insecticides; D009025:Morpholines; D011759:Pyrrolidines