title: A nanobody-based electrochemiluminescent immunosensor for sensitive detection of human procalcitonin.
abstract: The development of a nanobody-based electrochemiluminescent immunosensor for procalcitonin quantification is described. A highly specific and enhanced sensitivity of target detection was achieved by CdTe quantum dot encapsulated silica nanoparticle-assisted signal amplification.
authors.affiliation: School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China. liusq@seu.edu.cn.
authors.forename: Henan
authors.initials: H
authors.lastname: Li
authors.forename: Yanyan
authors.initials: Y
authors.lastname: Sun
authors.forename: Jelle
authors.initials: J
authors.lastname: Elseviers
authors.forename: Serge
authors.initials: S
authors.lastname: Muyldermans
authors.forename: Songqin
authors.initials: S
authors.lastname: Liu
authors.forename: Yakun
authors.initials: Y
authors.lastname: Wan
mesh_terms: D000595:Amino Acid Sequence; D015374:Biosensing Techniques / Q000295:instrumentation; D019187:Cadmium Compounds / Q000737:chemistry*; D002116:Calcitonin / Q000032:analysis / Q000097:blood*; D015740:Calcitonin Gene-Related Peptide; D055664:Electrochemical Techniques / Q000295:instrumentation*; D004867:Equipment Design; D006801:Humans; D007118:Immunoassay / Q000295:instrumentation; D057230:Limit of Detection; D008163:Luminescent Measurements / Q000295:instrumentation*; D008969:Molecular Sequence Data; D053758:Nanoparticles / Q000737:chemistry*; D011498:Protein Precursors / Q000032:analysis / Q000097:blood*; D045663:Quantum Dots / Q000737:chemistry; D012822:Silicon Dioxide / Q000737:chemistry*; D013691:Tellurium / Q000737:chemistry*
chemical_list: C000606589:CALCA protein, human; D019187:Cadmium Compounds; D011498:Protein Precursors; D012822:Silicon Dioxide; D002116:Calcitonin; D015740:Calcitonin Gene-Related Peptide; D013691:Tellurium; C028337:cadmium telluride