title: Assessment of mitral regurgitation severity by Doppler color flow mapping of the vena contracta in dogs.
abstract: BACKGROUND
  Quantitative and semiquantitative methods have been proposed for the assessment of MR severity, and though all are associated with limitations. Measurement of vena contracta width (VCW) has been used in clinical practice.
  
  
  OBJECTIVE
  To measure the VCW in dogs with different levels of MR severity.
  
  
  METHODS
  Two hundred and seventy-nine dogs were classified according to 5 levels of MR severity.
  
  
  METHODS
  This was a retrospective study. EROA and regurgitant volume calculated by the PISA method, were measured and indexed to BSA. Descriptive statistics were calculated for VCW and VCW index for all categories of MR severity. Spearman's rank correlation coefficients (ρs ) were calculated to compare the results of the different methods (VCW and VCW index vs RV PISA, RV PISA index, EROA, EROA index), and between VCW and VCW index versus MR severity.
  
  
  RESULTS
  All Spearman's rank correlation coefficients were significant (P < .001). The median values of VCW resulted of 2.9 mm (IQR 3.4-2.5) and of 4.6 mm (IQR 5.4-4.1) in the groups previously classified as mild-to-moderate and moderate-to-severe, respectively. The median values of VCW index resulted of 4.4 mm/m(2) (IQR = 5.5-4.2) in mild-to-moderate MR and of 10.8 mm/m(2) (IQR = 12.8-9.4) in moderate-to-severe MR.
  
  
  CONCLUSIONS
  This is not a validation study against any previously validated invasive gold standard, the VCW method has proved easy to employ and it might be an additional tool in quantifying disease severity that supports, rather than replace, data coming from other techniques in daily clinical practice and research.
authors.affiliation: Centro Medico Veterinario Cellatica, Cellatica, Brescia, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Di Marcello
authors.forename: E
authors.initials: E
authors.lastname: Terzo
authors.forename: C
authors.initials: C
authors.lastname: Locatelli
authors.forename: V
authors.initials: V
authors.lastname: Palermo
authors.forename: E
authors.initials: E
authors.lastname: Sala
authors.forename: E
authors.initials: E
authors.lastname: Dall'Aglio
authors.forename: C M
authors.initials: CM
authors.lastname: Bussadori
authors.forename: I
authors.initials: I
authors.lastname: Spalla
authors.forename: P G
authors.initials: PG
authors.lastname: Brambilla
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000000981:diagnostic imaging* / Q000503:physiopathology; D004285:Dogs; D018618:Echocardiography, Doppler, Color / Q000662:veterinary; D006439:Hemodynamics / Q000502:physiology; D017078:Laser-Doppler Flowmetry / Q000662:veterinary; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000503:physiopathology; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000662:veterinary*; D012189:Retrospective Studies; D012720:Severity of Illness Index
keywords: Congestive heart failure; Degenerative mitral valve disease; Vena contracta width