title: Management of neonatal proptosis: a systematic review.
abstract: Gross proptosis presenting at birth is an uncommon manifestation of a variety of lesions that can compromise vision and result in disfigurement or even loss of life. Notably, many disease entities have different presentations and prognoses in neonates compared to older children. A structured mental framework is essential to an efficient and coordinated response. We present three challenging cases of neonatal proptosis and discuss the clinical presentation and biological behavior of the lesions that are most often implicated.
authors.affiliation: Bascom Palmer Eye Institute, Miami, Florida, United States.
authors.forename: Benjamin P
authors.initials: BP
authors.lastname: Erickson
authors.affiliation: Bascom Palmer Eye Institute, Miami, Florida, United States. Electronic address: dtse@med.miami.edu.
authors.forename: David T
authors.initials: DT
authors.lastname: Tse
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000378:metabolism; D017024:Chemotherapy, Adjuvant; D003560:Cysts / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D005094:Exophthalmos / Q000209:etiology / Q000601:surgery*; D017809:Fatal Outcome; D005260:Female; D005354:Fibrosarcoma / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009447:Neuroblastoma / Q000150:complications / Q000556:secondary / Q000601:surgery*; D017233:Orbit Evisceration; D009916:Orbital Diseases / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D009918:Orbital Neoplasms / Q000150:complications / Q000556:secondary / Q000601:surgery*; D016216:Ultrasonography, Prenatal; D055815:Young Adult
chemical_list: D014408:Biomarkers, Tumor
keywords: fetal ultrasound; globe-sparing surgery; neonatal proptosis; orbital tumor