title: Drug-induced gastrointestinal disorders.
abstract: Drug-induced gastrointestinal disorders can mimic conditions, such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) and, hence, recognition can prevent unnecessary investigations and treatment. While the knowledge and awareness relating to the adverse gastrointestinal effects of some medications, such as non-steroidal anti-inflammatory drugs are well established, other commonly prescribed drugs, such as antipsychotics, antidepressants and metformin are less well understood and warrant further study. This review attempts to integrate recent information regarding adverse drug reactions and place this in a useful clinical context.
authors.affiliation: Department of Gastroenterology, Monash University, Eastern Health, Melbourne, Victoria, Australia Box Hill Hospital, Melbourne, Australia The Alfred Hospital, Melbourne, Australia.
authors.forename: H L
authors.initials: HL
authors.lastname: Philpott
authors.affiliation: Department of Gastroenterology, Monash University, Eastern Health, Melbourne, Victoria, Australia Box Hill Hospital, Melbourne, Australia.
authors.forename: S
authors.initials: S
authors.lastname: Nandurkar
authors.affiliation: Department of Gastroenterology, Monash University, Eastern Health, Melbourne, Victoria, Australia Box Hill Hospital, Melbourne, Australia.
authors.forename: J
authors.initials: J
authors.lastname: Lubel
authors.affiliation: Department of Gastroenterology, Monash University, Eastern Health, Melbourne, Victoria, Australia Box Hill Hospital, Melbourne, Australia The Alfred Hospital, Melbourne, Australia.
authors.forename: P R
authors.initials: PR
authors.lastname: Gibson
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D000928:Antidepressive Agents / Q000008:administration & dosage*; D014150:Antipsychotic Agents / Q000009:adverse effects*; D004334:Drug Administration Schedule; D005765:Gastrointestinal Agents / Q000009:adverse effects*; D005767:Gastrointestinal Diseases / Q000139:chemically induced*; D006801:Humans; D015212:Inflammatory Bowel Diseases; D043183:Irritable Bowel Syndrome; D008687:Metformin / Q000009:adverse effects*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D005765:Gastrointestinal Agents; D008687:Metformin
keywords: Adverse Drug Reactions; Clinical Decision Making; Colorectal Motility; Crohn'S Disease; Diarrhoea