title: [Driver genes and its clinical significance in non-small cell lung cancer].
abstract: With the development of molecular biology technology and the transforming patterns of drug research, guiding molecular targeted therapy according to the drive gene mutation spectrum in lung cancer has gradually become a reality. Definition of the mutation incidence and whether existing advantage population groups in non-small cell lung cancer (NSCLC) have important guiding significance in clinical practice. The purpose of this paper will draw a summary on the general characteristics, demographic features and clinical significance of driver genes in NSCLC.
authors.affiliation: Seven-Year System, Clinical Medicine, China Medical University, Shenyang 110001, China.
authors.forename: Yuequan
authors.initials: Y
authors.lastname: Shi
authors.affiliation: Department of Pathology, Shengjing Hospital, China Medical University, Shenyang 110004, China.
authors.forename: Xianghong
authors.initials: X
authors.lastname: Yang
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy / Q000235:genetics*; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000235:genetics*; D058990:Molecular Targeted Therapy; D009154:Mutation
chemical_list: D000970:Antineoplastic Agents