title: BRAF(V600) mutation levels predict response to vemurafenib in metastatic melanoma.
authors.affiliation: aAP-HP, Department of Dermatology, Saint-Louis Hospital bParis-Diderot University, Sorbonne Paris Cite cINSERM U976 dLaboratory for Functional Genomics, Jean Dausset Fondation - CEPH eAP-HP, Pathology Laboratory, Saint-Louis Hospital, INSERM UMR_S 1165 fAP-HP, Saint-Louis Hospital, Pharmacology-Genetic Laboratory gDepartment of Biostatistics and Medical Data Processing, INSERM-U717 hLaboratory for Epigenetics and Environment, Genotyping National Center, CEA, Genomic Institute iINSERM UMR-S 940, Paris, France.
authors.forename: Celeste
authors.initials: C
authors.lastname: Lebbé
authors.forename: Alexandre
authors.initials: A
authors.lastname: How-Kit
authors.forename: Maxime
authors.initials: M
authors.lastname: Battistella
authors.forename: Aurelie
authors.initials: A
authors.lastname: Sadoux
authors.forename: Marie-Pierre
authors.initials: MP
authors.lastname: Podgorniak
authors.forename: Irina
authors.initials: I
authors.lastname: Sidina
authors.forename: Cécile
authors.initials: C
authors.lastname: Pages
authors.forename: Jennifer
authors.initials: J
authors.lastname: Roux
authors.forename: Raphael
authors.initials: R
authors.lastname: Porcher
authors.forename: Jorg
authors.initials: J
authors.lastname: Tost
authors.forename: Samia
authors.initials: S
authors.lastname: Mourah
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D018450:Disease Progression; D005260:Female; D006801:Humans; D007211:Indoles / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008545:Melanoma / Q000188:drug therapy* / Q000201:enzymology / Q000235:genetics; D009154:Mutation; D009362:Neoplasm Metastasis; D048493:Proto-Oncogene Proteins B-raf / Q000235:genetics* / Q000378:metabolism; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000201:enzymology / Q000235:genetics; D013449:Sulfonamides / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome; D000077484:Vemurafenib
chemical_list: D000970:Antineoplastic Agents; D007211:Indoles; D013449:Sulfonamides; D000077484:Vemurafenib; C482119:BRAF protein, human; D048493:Proto-Oncogene Proteins B-raf