title: Pharmacology of pain.
abstract: This article discusses the mechanisms of action of the main drugs used to treat pain, in particular inflammatory pain. The drugs are described following a classification based on the steps of pain processing that they primarily affect.
authors.affiliation: Department of Medical Biotechnologies and Translational Medicine, University of Milan. diego.fornasari@unimi.it.
authors.forename: D
authors.initials: D
authors.lastname: Fornasari
authors.forename: S
authors.initials: S
authors.lastname: Coaccioli
mesh_terms: D000700:Analgesics / Q000494:pharmacology / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001921:Brain / Q000503:physiopathology; D059333:Central Nervous System Sensitization / Q000187:drug effects / Q000502:physiology; D059350:Chronic Pain / Q000188:drug therapy* / Q000503:physiopathology; D004361:Drug Tolerance; D006801:Humans; D062559:NAV1.8 Voltage-Gated Sodium Channel / Q000187:drug effects / Q000502:physiology; D036421:Nerve Fibers, Unmyelinated / Q000187:drug effects / Q000502:physiology; D009431:Neural Conduction / Q000187:drug effects / Q000502:physiology; D009619:Nociceptors / Q000502:physiology; D059408:Pain Management; D058748:Pain Perception / Q000502:physiology; D020671:Posterior Horn Cells / Q000187:drug effects / Q000502:physiology; D011453:Prostaglandins / Q000502:physiology; D011957:Receptors, Opioid / Q000187:drug effects / Q000502:physiology; D050916:TRPV Cation Channels / Q000187:drug effects / Q000502:physiology
chemical_list: D000700:Analgesics; D000893:Anti-Inflammatory Agents; D062559:NAV1.8 Voltage-Gated Sodium Channel; D011453:Prostaglandins; D011957:Receptors, Opioid; C568317:SCN10A protein, human; D050916:TRPV Cation Channels; C494482:TRPV1 protein, human