title: [A matched case-control study of risk factors in abdominal aortic aneurysm].
abstract: OBJECTIVE
  To examine the potential influence factors of abdominal aortic aneurysm (AAA).
  
  
  METHODS
  A 1:2 pair-matched, case-control study was conducted from July 2011 to December 2012. A pair was composed of one AAA patient recruited from the Vascular Surgery Department, Chinese PLA General Hospital and two gender- and age-matched non-AAA subjects, one from the same hospital and the other from the community in Fangshan District in Beijing. Demographic data, medical history and the lifestyle of each subject were collected. Moreover, all the participants underwent abdominal ultrasound or computed tomography (CT) and peripheral venous blood samples were obtained.
  
  
  RESULTS
  There were 155 case/control pairs. The multivariate conditional logistic regression model confirmed that suffering from hypertension conferred a 1.98-fold (95%CI 1.12-3.18) increased likelihood of AAA. Smoking was a strong independent risk factor of AAA, with odds ratios (95% confidence intervals) of 5.23 (2.44-11.23). Dyslipidemia (OR=2.61,95% CI 1.45-4.70), a higher level of serum hsCRP (OR=2.43,95%CI 1.37-4.31) and homocysteine (OR=2.73,95% CI 1.61-4.65) were all associated with AAA.
  
  
  CONCLUSIONS
  Hypertension and smoking are the risk factors of AAA. Dyslipidemia, hsCRP and Hcy are associated with AAA.
authors.affiliation: Department of Vascular & Endovascular Surgery, PLA General Hospital, Beijing 100853, China.
authors.forename: Shang-wei
authors.initials: SW
authors.lastname: Zuo
authors.affiliation: Department of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
authors.forename: Ying-qi
authors.initials: YQ
authors.lastname: Wei
authors.affiliation: Department of Vascular & Endovascular Surgery, PLA General Hospital, Beijing 100853, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Chen
authors.affiliation: Department of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
authors.forename: Da-fang
authors.initials: DF
authors.lastname: Chen
authors.affiliation: Department of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Wu
authors.affiliation: Department of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
authors.forename: Kuo
authors.initials: K
authors.lastname: Liu
authors.affiliation: Department of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
authors.forename: Ke-xin
authors.initials: KX
authors.lastname: Sun
authors.affiliation: Department of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Juan
authors.affiliation: Department of Vascular & Endovascular Surgery, PLA General Hospital, Beijing 100853, China.
authors.forename: Jiang
authors.initials: J
authors.lastname: Xiong
authors.affiliation: Department of Vascular & Endovascular Surgery, PLA General Hospital, Beijing 100853, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Guo
mesh_terms: D017544:Aortic Aneurysm, Abdominal / Q000453:epidemiology*; D044466:Asian People; D002097:C-Reactive Protein / Q000378:metabolism; D016022:Case-Control Studies; D050171:Dyslipidemias; D006710:Homocysteine / Q000097:blood; D006801:Humans; D006973:Hypertension; D016015:Logistic Models; D016017:Odds Ratio; D012307:Risk Factors; D012907:Smoking; D014057:Tomography, X-Ray Computed
chemical_list: D006710:Homocysteine; D002097:C-Reactive Protein