title: Giant chorioangioma treated in utero via laser of feeding vessels with subsequent development of multifocal infantile hemangiomas.
abstract: We report a case of a giant placental chorioangioma (15.6 cm diameter) complicated by polyhydramnios and severe fetal heart failure. Fetoscopic laser occlusion of a dominant feeding vessel was performed at 29 weeks' gestation and partial devascularization was achieved. In the 33rd week of the pregnancy, the decision was made to preemptively deliver the fetus due to persistent signs of fetal cardiac failure. After birth, the infant developed multifocal infantile hemangiomas with extracutaneous involvement. We posit that the development of infantile hemangiomas may be linked to the presence of the large chorioangioma. Further study is required to ascertain if fetal treatment of the chorioangioma may have been an exacerbating factor.
authors.affiliation: 1Department of Pediatrics, Division of Neonatal Medicine, Los Angeles County + University of Southern California, Keck School of Medicine, Los Angeles, CA, USA.
authors.forename: Katrina M
authors.initials: KM
authors.lastname: Jhun
authors.forename: Paulo
authors.initials: P
authors.lastname: Nassar
authors.forename: Tina S
authors.initials: TS
authors.lastname: Chen
authors.forename: Smeeta
authors.initials: S
authors.lastname: Sardesai
authors.forename: Ramen H
authors.initials: RH
authors.lastname: Chmait
mesh_terms: D000328:Adult; D005260:Female; D005332:Fetoscopy; D006333:Heart Failure / Q000150:complications / Q000196:embryology* / Q000628:therapy*; D006391:Hemangioma / Q000150:complications / Q000175:diagnosis* / Q000196:embryology / Q000628:therapy*; D006801:Humans; D007231:Infant, Newborn; D007834:Lasers; D008297:Male; D010922:Placenta Diseases / Q000175:diagnosis* / Q000628:therapy*; D006831:Polyhydramnios / Q000175:diagnosis* / Q000628:therapy*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D011256:Pregnancy Outcome; D016896:Treatment Outcome
keywords: chorioangioma; fetal treatment; fetoscopy; hemangioma; placental tumor