title: Cluster of Escherichia coli isolates producing a plasmid-mediated OXA-48 β-lactamase in a Spanish hospital in 2012.
abstract: Three unrelated sequence type 131 (ST131), ST58, and ST83 Escherichia coli isolates with low-level resistance to imipenem and resistance to ertapenem were recovered in a Spanish hospital from July to October 2012. They were positive for blaOXA-48 carried by an IncL/M conjugative plasmid, which may have been acquired from Klebsiella pneumoniae.
authors.affiliation: Department of Functional Biology, Section of Microbiology, University of Oviedo, Oviedo, Spain Service of Microbiology, Hospital Universitario Central de Asturias, Oviedo, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Fernández
authors.affiliation: Department of Functional Biology, Section of Microbiology, University of Oviedo, Oviedo, Spain.
authors.forename: Ignacio
authors.initials: I
authors.lastname: Montero
authors.affiliation: Service of Microbiology, Hospital Universitario Central de Asturias, Oviedo, Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Fleites
authors.affiliation: Department of Functional Biology, Section of Microbiology, University of Oviedo, Oviedo, Spain rrodicio@uniovi.es.
authors.forename: M Rosario
authors.initials: MR
authors.lastname: Rodicio
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003227:Conjugation, Genetic; D000077727:Ertapenem; D004926:Escherichia coli / Q000145:classification / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000382:microbiology*; D029968:Escherichia coli Proteins; D005260:Female; D022761:Gene Transfer, Horizontal; D005838:Genotype; D006761:Hospitals; D006801:Humans; D015378:Imipenem / Q000494:pharmacology; D008297:Male; D008875:Middle Aged; D010957:Plasmids / Q000032:analysis; D013030:Spain / Q000453:epidemiology; D001618:beta-Lactamases / Q000235:genetics*; D047090:beta-Lactams / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D029968:Escherichia coli Proteins; D047090:beta-Lactams; D015378:Imipenem; D001618:beta-Lactamases; C000601047:beta-lactamase OXA-48, E coli; C108449:oxacillinase; D000077727:Ertapenem