title: Glasgow prognostic score is a useful predictive factor of outcome after palliative gastrectomy for stage IV gastric cancer.
abstract: OBJECTIVE
  The Glasgow prognostic score (GPS) is a predictor of outcome for several cancer types. The present study examined the significance of modified GPS (mGPS) in the prognosis of patients undergoing palliative surgery for stage IV gastric cancer.
  
  
  METHODS
  A total of 42 patients with stage IV gastric cancer treated with palliative gastrectomy and gastrojejunostomy were included in the study. Univariate and multivariate analyses were performed to evaluate the relationship between clinicopathological factors and cancer-specific survival (CS).
  
  
  RESULTS
  Among patients who underwent palliative surgery including gastrectomy and gastrojejunostomy, univariate analysis of CS identified the following significant risk factors: surgical treatment, chemotherapy and mGPS, and multivariate analysis revealed that mGPS was independently-associated with CS. In particular, among patients who underwent palliative gastrectomy, mGPS was shown to be the strongest independent predictive factor for CS.
  
  
  CONCLUSIONS
  The mGPS was an independent predictive factor for survival in patients who underwent palliative surgery for stage IV incurable gastric cancer, especially for those who underwent palliative gastrectomy.
authors.affiliation: Department of Surgery, Social Insurance Yokohama Central Hospital, Kanagawa, Japan mimatsu.kenji@yokochu.jp.
authors.forename: Kenji
authors.initials: K
authors.lastname: Mimatsu
authors.affiliation: Department of Surgery, Social Insurance Yokohama Central Hospital, Kanagawa, Japan.
authors.forename: Takatsugu
authors.initials: T
authors.lastname: Oida
authors.affiliation: Department of Surgery, Social Insurance Yokohama Central Hospital, Kanagawa, Japan.
authors.forename: Nobutada
authors.initials: N
authors.lastname: Fukino
authors.affiliation: Department of Surgery, Social Insurance Yokohama Central Hospital, Kanagawa, Japan.
authors.forename: Hisao
authors.initials: H
authors.lastname: Kano
authors.affiliation: Department of Surgery, Social Insurance Yokohama Central Hospital, Kanagawa, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kawasaki
authors.affiliation: Department of Surgery, Social Insurance Yokohama Central Hospital, Kanagawa, Japan.
authors.forename: Kazutoshi
authors.initials: K
authors.lastname: Kida
authors.affiliation: Department of Surgery, Social Insurance Yokohama Central Hospital, Kanagawa, Japan.
authors.forename: Youichi
authors.initials: Y
authors.lastname: Kuboi
authors.affiliation: Department of Surgery, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: Sadao
authors.initials: S
authors.lastname: Amano
mesh_terms: D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery; D008175:Lung Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery; D008207:Lymphatic Metastasis; D008297:Male; D009367:Neoplasm Staging; D010166:Palliative Care; D010534:Peritoneal Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery; D011379:Prognosis; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D015996:Survival Rate
keywords: Glasgow prognostic score; Stage IV gastric cancer; palliative gastrectomy