title: Prevalence of hepatitis B virus in patients with diabetes mellitus: a comparative cross sectional study at Woldiya General Hospital, Ethiopia.
abstract: BACKGROUND
  The overall prevalence of HBV in Ethiopia varies from 4.7-16.8% for Hepatitis B surface antigen (HBsAg) and 70-76.38% for at least one marker positive. Patients suffering from type I Diabetes Mellitus (DM) incur high risk of infection with hepatotropic viruses because of frequent hospitalization and blood tests.
  
  
  METHODS
  A comparative cross sectional study was conducted at Woldiya General Hospital using 108 consented study populations from Diabetes and 108 non diabetes control groups during the period November 2010 - January 2011. VISITECT HBsAg rapid test kit and Humastat 80 chemistry analyzer were used. Multivariate logistic regression was used to see the association of HBV with clinical history of participants and Sociodemographic variables. All tests were two-sided with α-level of 0.05 and 80% power.
  
  
  RESULTS
  Prevalence of HBsAg was equal between diabetic and non diabetic individuals, 3.7% indicating that there was no difference between the two groups. Only history of invasive procedures and chronic liver disease showed association with HBsAg seropositivity.
  
  
  CONCLUSIONS
  In this study a positive relation was not indicated between HBV and Diabetes and the prevalence of HBsAg was equal between diabetic and non diabetic individuals.
authors.affiliation: Bahir Dar Regional Health Research Laboratory Center, Bahir Dar, Ethiopia ; Department of Medical Microbiology, Immunology and Parasitology College of Health Science, School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
authors.forename: Daniel
authors.initials: D
authors.lastname: Mekonnen
authors.affiliation: Department of Medical Microbiology, Immunology and Parasitology College of Health Science, School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
authors.forename: Solomon
authors.initials: S
authors.lastname: Gebre-Selassie
authors.affiliation: Ethiopian Health and Nutrition Research Institute Bacteriology and Mycology Laboratory, Addis Ababa, Ethiopia.
authors.forename: Surafel
authors.initials: S
authors.lastname: Fantaw
authors.affiliation: Amhara National Regional State Health Bureau, Woldiya General Hospital, Woldiya, Ethiopia.
authors.forename: Andualem
authors.initials: A
authors.lastname: Hunegnaw
authors.affiliation: Department of Medical Microbiology, Immunology and Parasitology College of Health Science, School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia ; Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
authors.forename: Adane
authors.initials: A
authors.lastname: Mihret
mesh_terms: D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D048909:Diabetes Complications / Q000453:epidemiology* / Q000821:virology; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000453:epidemiology* / Q000821:virology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000453:epidemiology* / Q000821:virology; D005002:Ethiopia / Q000453:epidemiology; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology*; D006515:Hepatitis B virus / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D055815:Young Adult
keywords: HBV; Prevalence; association; diabetes; non diabetes