title: Central giant cell granuloma in pediatric maxilla: surgical management.
abstract: Central giant cell granuloma (CGCG) is an intraosseous lesion consisting of fibrous cellular tissue that contains multiple foci of hemorrhage, multinucleated giant cells, and occasional trabeculae of woven bone. An 8-year-old boy presented himself complaining of a painless swelling in the left maxilla that had started 1 year. Computed tomography (CT) scan confirmed a poorly defined multilocular radiolucent lesion in the left maxilla crossing the midline. The patient underwent enucleation through an intraoral approach of the lesion. The biopsy revealed multinucleated giant cells in a fibrous stroma. A CT was taken approximately 1 year postoperatively. There was no clinical or radiographic evidence of recurrence. Therefore, surgical treatment of CGCG can be performed, trying to preserve the surrounding anatomic structures, which can be maintained in case the lesion does not show an aggressive clinical behavior, avoiding large surgical defects which are undesirable in children.
authors.affiliation: From the Division of Oral and Maxillofacial Surgery, Department of Surgery and Integrated Clinic, Aracatuba Dental School, Univ Estadual Paulista - Julio de Mesquita Filho - UNESP, Araçatuba, Brazil.
authors.forename: Leonardo Perez
authors.initials: LP
authors.lastname: Faverani
authors.forename: Sabrina
authors.initials: S
authors.lastname: Ferreira
authors.forename: Gabriel Ramalho
authors.initials: GR
authors.lastname: Ferreira
authors.forename: Juliana Zorzi
authors.initials: JZ
authors.lastname: Coléte
authors.forename: Alessandra Marcondes
authors.initials: AM
authors.lastname: Aranega
authors.forename: Idelmo Rangel
authors.initials: IR
authors.lastname: Garcia Júnior
mesh_terms: D001706:Biopsy; D002648:Child; D005500:Follow-Up Studies; D015726:Giant Cells / Q000473:pathology; D006101:Granuloma, Giant Cell / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008297:Male; D008437:Maxilla / Q000473:pathology / Q000601:surgery; D008439:Maxillary Diseases / Q000473:pathology* / Q000601:surgery*; D014057:Tomography, X-Ray Computed