title: Diagnosis and Treatment of a Preterm Infant With Inoperable Congenital Hepatoblastoma--A Case Report.
abstract: Reports of hepatoblastoma (HB) in preterm infants are quite rare. Herein, we report the clinical management of a preterm infant with inoperable congenital HB. A female fetus that had been diagnosed with a large liver tumor consistent with hemangioma was delivered by emergency cesarean section at 33 weeks of gestation because of fetal distress. Effective antitumor therapy could not be performed, resulting in rapid deterioration and death. The postmortem histopathologic analysis confirmed the tumor as a HB. This report demonstrates the difficulties inherent in both the image diagnosis of HB and in providing efficacious treatments for preterm infants with HB.
authors.affiliation: Departments of *Neonatology †Radiology ‡Clinical Pathology §Maternal and Fetal Medicine, Miyagi Children's Hospital ∥Department of Maternal and Fetal Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Miura
authors.forename: Junko
authors.initials: J
authors.lastname: Saito
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Shimanuki
authors.forename: Junji
authors.initials: J
authors.lastname: Takeyama
authors.forename: Jun
authors.initials: J
authors.lastname: Murotsuki
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017809:Fatal Outcome; D005260:Female; D018197:Hepatoblastoma / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000188:drug therapy*