title: [Integrative pharmacology: new paradigm of modernization of Chinese medicine].
abstract: Chinese medicinal formulae( CMF) were often used in the clinics of traditional Chinese medicine (TCM) which were critical for modernization of Chinese medicine to shed light on the interaction between CMF and biological organisms. In current studies, correlation between system and part, macroscopic actions and microcosmic mechanism, ADME process and pharmacologic actions were often neglected. Thus, we put forward integrative pharmacology, which could integrate the correlation between CMF and biological organisms from multi-levels and multi-dimensional views. Integrative pharmacology would reveal the molecular mechanism of CMF for ailments treatment and screen out effective material systematically, which would be the new paradigm of TCM research.
authors.forename: Hai-Yu
authors.initials: HY
authors.lastname: Xu
authors.forename: Hong-Jun
authors.initials: HJ
authors.lastname: Yang
mesh_terms: D000042:Absorption; D019295:Computational Biology; D008516:Medicine, Chinese Traditional / Q000379:methods* / Q000639:trends; D010600:Pharmacology / Q000379:methods* / Q000639:trends; D014018:Tissue Distribution