title: Silver binding nucleolar organizer regions dots in oral leukoplakia with epithelial dysplasia and oral squamous cell carcinoma: an in vivo study.
abstract: Silver binding nucleolar organizer regions (AgNOR) in normal oral mucosa (NOM), oral leukoplakia with epithelial dysplasia (ED), and oral squamous cell carcinoma (OSCC) were studied. The mean AgNOR count per nucleus increased from NOM to ED to OSCC. Tissue showing ED in oral leukoplakia and OSCC cases showed higher counts, wider scatter, and smaller size of AgNOR dots in the nuclei. The study seems to suggest that time method has some potential in distinguishing between NOM and oral leukoplakia with ED and OSCC. Studies of larger numbers are needed to arrive at more substantial conclusions.
authors.affiliation: Department of Oral Pathology & Microbiology, King George's Medical University, Lucknow, India.
authors.forename: Fahad
authors.initials: F
authors.lastname: Mansoor Samadi
authors.affiliation: Department of Oral Pathology & Microbiology, Mahe Institute of Dental Sciences, Palloor, Mahe, Puducherry, India.
authors.forename: Bastain
authors.initials: B
authors.lastname: Thattil Sebastian
authors.affiliation: Department of Oral Pathology & Microbiology, Saraswati Dental College, Lucknow, India.
authors.forename: Anil
authors.initials: A
authors.lastname: Singh
authors.affiliation: Department of Oral Pathology & Microbiology, King George's Medical University, Lucknow, India.
authors.forename: Shaleen
authors.identifier: 0000-0002-5180-6341
authors.initials: S
authors.lastname: Chandra
authors.affiliation: Department of Oral & Maxillofacial Surgery, King George's Medical University, Lucknow, India.
authors.forename: Shadab
authors.initials: S
authors.lastname: Mohammad
authors.affiliation: Department of Oral Pathology & Microbiology, Kothiwal Dental College & Research Centre, Moradabad, Uttar Pradesh, India.
authors.forename: Arun
authors.initials: A
authors.lastname: Singh
authors.affiliation: Department of Oral Pathology & Microbiology, Babu Banarsi Das College of Dental Sciences, Lucknow, India.
authors.forename: Thippeswamy
authors.initials: T
authors.lastname: Halappa
authors.affiliation: Department of Pedodontics, Career Post Graduate Institute of Dental Sciences and Hospital, Lucknow, Uttar Pradesh, India.
authors.forename: Firoza
authors.initials: F
authors.lastname: Samadi