title: Hormonal manipulation with letrozole in the treatment of metastatic malignant pecoma.
abstract: Perivascular epithelioid cell tumours (pecomas) are rare mesenchymal tumours. Some have a benign course; others metastasize. Treatment of malignant pecomas is challenging, and little is known about treatment for patients with metastatic disease. Here, we report a case of metastatic malignant pecoma with estrogen and progesterone receptor expression that showed a favourable and sustained response to letrozole.
authors.affiliation: Department of Medical Oncology, Jewish General Hospital (a McGill University affiliate), Montreal, QC.
authors.forename: P
authors.initials: P
authors.lastname: Le
authors.affiliation: Department of Medical Oncology, Jewish General Hospital (a McGill University affiliate), Montreal, QC.
authors.forename: A
authors.initials: A
authors.lastname: Garg
authors.affiliation: Department of Pathology, Jewish General Hospital (a McGill University affiliate), Montreal, QC.
authors.forename: G
authors.initials: G
authors.lastname: Brandao
authors.affiliation: Department of Medical Oncology, Jewish General Hospital (a McGill University affiliate), Montreal, QC.
authors.forename: A
authors.initials: A
authors.lastname: Abu-Sanad
authors.affiliation: Department of Medical Oncology, Jewish General Hospital (a McGill University affiliate), Montreal, QC.
authors.forename: L
authors.initials: L
authors.lastname: Panasci
keywords: Malignant pecoma; estrogen; letrozole; metastasis; pecoma; progesterone; receptors; sirolimus