title: Tuberculosis of the Cuboid: A Case Report and Review of the Literature.
abstract: Tuberculosis (TB) remains a major global health problem. According to a recent World Health Organization report, it ranks as the second leading cause of death from an infectious disease worldwide. According to the "UK Health Protection Agency Tuberculosis in the UK: 2012 Report," 8963 cases were reported in the United Kingdom in 2011. London had the greatest proportion of cases in the United Kingdom and the greatest rate of disease. TB affecting the foot is rare, affecting about 10% of all skeletal TB cases. However, owing to the current patterns of global immigration, with significant volumes of people migrating out of endemic countries, it has become a disease that physicians and surgeons in developed countries should be more aware of in today's practice. To the best of our knowledge, we present the first adult case of TB of the cuboid in the United Kingdom and the first adult case documented outside of India. We present the case details and the results of a thorough review of the literature. TB of the foot and ankle poses a diagnostic challenge because of the propensity of TB to mimic other pathologic entities radiologically. Tissue diagnosis and antitubercular medication is the mainstay of diagnosis and treatment, respectively.
authors.affiliation: Specialist Registrar, Trauma and Orthopaedics, Barking, Havering and Redbridge National Health Service Trust, London, United Kingdom.
authors.forename: Luckshmana
authors.initials: L
authors.lastname: Jeyaseelan
authors.affiliation: Specialist Registrar, Trauma and Orthopaedics, Barking, Havering and Redbridge National Health Service Trust, London, United Kingdom.
authors.forename: Daniel
authors.initials: D
authors.lastname: Williams
authors.affiliation: Senior Orthopaedic Registrar, Department of Trauma and Orthopaedics, Barking, Havering and Redbridge National Health Service Trust, London, United Kingdom.
authors.forename: Saket
authors.initials: S
authors.lastname: Tibrewal
authors.affiliation: Associate Specialist, Department of Trauma and Orthopaedics, Barking, Havering and Redbridge National Health Service Trust, London, United Kingdom.
authors.forename: Syed Asif
authors.initials: SA
authors.lastname: Ali
authors.affiliation: Associate Specialist, Department of Trauma and Orthopaedics, Barking, Havering and Redbridge National Health Service Trust, London, United Kingdom.
authors.forename: Mahmood
authors.initials: M
authors.lastname: Hassan
authors.affiliation: Consultant Orthopaedic Surgeon, Department of Trauma and Orthopaedics, Barking, Havering and Redbridge National Health Service Trust, London, United Kingdom. Electronic address: kvorthopaedics@gmail.com.
authors.forename: Krishna
authors.initials: K
authors.lastname: Vemulapalli
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D003920:Diabetes Mellitus; D003952:Diagnostic Imaging; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D013639:Tarsal Bones / Q000382:microbiology*; D014394:Tuberculosis, Osteoarticular / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents
keywords: Mycobacterium tuberculosis; antitubercular therapy; infection; osteomyelitis; skeletal tuberculosis