title: Determining the time required to achieve negative human chorionic gonadotropin value after a nonmolar pregnancy: preliminary results.
abstract: OBJECTIVE
  To determine the time of human chorionic gonadotropin (hCG) regression in nonmolar gestation.
  
  
  METHODS
  Patients treated at our institution between June 2012 and July 2013 were selected by a deterministic sequential sampling distributed among 2 phases. Distribution of the patients included resolved cases by vaginal delivery and cesarean section in preterm and term pregnancies, ectopic, and abortion. Phase 1: serum hCG values were determined at 4, 5 and 6 weeks of obstetric resolution. Phase 2: hCG serum values were determined immediately at obstetric resolution and at 2, 3 and 4 weeks of the resolution of the cases, too.
  
  
  RESULTS
  Phase 1: After the analysis of serum hCG of 63 patients at 4, 5 and 6 weeks postresolution, a negative result was corroborated in 100% of cases, in any period of the sample, with average values of 1.71, 0.55, and 0.18 mIU/mL, respectively. Phase 2 included 398 patients, with serum hCG in the first 72 hours postresolution, showing an average hCG value of 1,483.5 mIU/mL (range, 0.07-10,789), noting that 1% of cases had negative results. We then obtained hCG values at 2, 3 and 4 weeks of resolution, showing the regression in 73.4% of cases in the 2nd week, in 96.7% of patients in the 3rd week, and in all cases in the 4th week.
  
  
  CONCLUSIONS
  The regression of hCG after nonmolar pregnancy does not exceed 3 weeks.
authors.forename: Rafael
authors.initials: R
authors.lastname: Cortés-Charry
authors.forename: Nicol
authors.initials: N
authors.lastname: Corredor
authors.forename: Jessica
authors.initials: J
authors.lastname: Fernández
authors.forename: Aleydah
authors.initials: A
authors.lastname: Salazar
authors.forename: Lourdes
authors.initials: L
authors.lastname: Rodriguez
authors.forename: Margarita
authors.initials: M
authors.lastname: Fargione
mesh_terms: D000022:Abortion, Spontaneous / Q000097:blood; D000293:Adolescent; D000328:Adult; D002585:Cesarean Section; D006063:Chorionic Gonadotropin / Q000097:blood*; D036861:Delivery, Obstetric; D005260:Female; D005865:Gestational Age; D031901:Gestational Trophoblastic Disease / Q000097:blood; D006801:Humans; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000097:blood; D047928:Premature Birth / Q000097:blood; D013997:Time Factors
chemical_list: D006063:Chorionic Gonadotropin