title: An uncommon tail about the common γ-chain.
abstract: The common γ-chain (γc) is a key component of multiple cytokine receptors. In this issue of Immunity, Hong et al. (2014) demonstrate a unique function of γc as a secreted protein capable of inhibiting cytokine responses and promoting autoimmunity.
authors.affiliation: Center for Immunology, Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55414, USA. Electronic address: james024@umn.edu.
authors.forename: Stephen C
authors.initials: SC
authors.lastname: Jameson
authors.affiliation: Center for Immunology, Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55414, USA.
authors.forename: Kristin R
authors.initials: KR
authors.lastname: Renkema
mesh_terms: D017398:Alternative Splicing / Q000276:immunology*; D000818:Animals; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000276:immunology*; D007142:Immunoglobulin gamma-Chains / Q000276:immunology*; D007249:Inflammation / Q000276:immunology*; D058504:Th17 Cells / Q000276:immunology*
chemical_list: D007142:Immunoglobulin gamma-Chains