title: Self-assemble ZnMn2O4 hierarchical hollow microspheres into self-supporting architecture for enhanced biosensing performance.
abstract: We demonstrate a facile and scalable approach to fabricate and self-assemble the hierarchical hollow microspheres into self-supporting architecture by naturally grown branches. The supporting branches can afford integrated transport channels and significantly improve the kinetic performance and mechanical stability. Meanwhile, the supported hierarchical microspheres acting as functional cell can provide high active sites, multiple response and suitable environment for immobilizing biomolecules. Different enzymes are immobilized for biosensors. The experiments demonstrate that the effective assembly of hierarchical microspheres into large size ordered architecture by self-supporting branches can significantly enhance the biosensing performance.
authors.affiliation: Department of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Zhejiang University, Hangzhou 310027, China.
authors.forename: Minggang
authors.initials: M
authors.lastname: Zhao
authors.affiliation: Department of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Zhejiang University, Hangzhou 310027, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Cai
authors.affiliation: Department of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Zhejiang University, Hangzhou 310027, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Ma
authors.affiliation: Department of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Zhejiang University, Hangzhou 310027, China.
authors.forename: Hi
authors.initials: H
authors.lastname: Cai
authors.affiliation: Department of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Zhejiang University, Hangzhou 310027, China; Cyrus Tang Center for Sensor Materials and Applications, Zhejiang University, China. Electronic address: huangjy@zju.edu.cn.
authors.forename: Jingyun
authors.initials: J
authors.lastname: Huang
authors.affiliation: Department of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Zhejiang University, Hangzhou 310027, China.
authors.forename: Xinhua
authors.initials: X
authors.lastname: Pan
authors.affiliation: Department of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Zhejiang University, Hangzhou 310027, China.
authors.forename: Haiping
authors.initials: H
authors.lastname: He
authors.affiliation: Department of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Zhejiang University, Hangzhou 310027, China; Cyrus Tang Center for Sensor Materials and Applications, Zhejiang University, China. Electronic address: yezz@zju.edu.cn.
authors.forename: Zhizhen
authors.initials: Z
authors.lastname: Ye
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D055664:Electrochemical Techniques / Q000295:instrumentation; D004566:Electrodes; D017895:Manganese Compounds / Q000737:chemistry*; D008863:Microspheres; D010087:Oxides / Q000737:chemistry*; D016062:Porosity; D015032:Zinc / Q000737:chemistry*
chemical_list: D017895:Manganese Compounds; D010087:Oxides; C027424:manganese oxide; D015032:Zinc
keywords: Biosensor; Hierarchical structure; Hollow; Self-assemble; Self-supporting