title: Recent advances in polymeric electrospun nanofibers for drug delivery.
abstract: Electrospinning is a simple unit operation process by which polymeric nanofibers with diameters ranging from a few nanometers to hundreds of micrometers can be fabricated using an electrostatically operated jet of polymer solution or polymer melt. Nanofibers because of their interesting features, such as surface-to-volume ratio, high surface area, microporosity, and nonwoven structure, provide numerous opportunities to design novel carrier systems for large commodities of therapeutics. Physicochemical properties of nanofibers depend on several process and formulation parameters, such as applied voltage, flow rate, polymer selection, and concentration of polymer used. The applications of nanofibers in drug delivery are nearly unbounded. This review summarizes the most recent work done on the various physicochemical parameters of electrospinning and polymers used in making wide varieties of nanofibers along with their role in developing more effective, novel drug delivery systems.
authors.affiliation: Department of Pharmaceutics, I.S.F. College of Pharmacy, Moga (Punjab), India.
authors.forename: Rahul
authors.initials: R
authors.lastname: Sharma
authors.affiliation: Department of Pharmaceutics, I.S.F. College of Pharmacy, Moga (Punjab), India.
authors.forename: Harmanpreet
authors.initials: H
authors.lastname: Singh
authors.affiliation: Department of Pharmaceutics, I.S.F. College of Pharmacy, Moga (Punjab), India.
authors.forename: Munish
authors.initials: M
authors.lastname: Joshi
authors.affiliation: Department of Pharmaceutics, I.S.F. College of Pharmacy, Moga (Punjab), India.
authors.forename: Abhinandan
authors.initials: A
authors.lastname: Sharma
authors.affiliation: Department of Pharmaceutics, ISF College of Pharmacy, Moga (Punjab), India 09501223252(M).
authors.forename: Tarun
authors.initials: T
authors.lastname: Garg
authors.affiliation: Department of Pharmaceutics, ISF College of Pharmacy, Moga (Punjab), India.
authors.forename: Amit Kumar
authors.initials: AK
authors.lastname: Goyal
authors.affiliation: Department of Pharmaceutics, ISF College of Pharmacy, Moga, Punjab.
authors.forename: Goutam
authors.initials: G
authors.lastname: Rath
mesh_terms: D002626:Chemistry, Pharmaceutical; D004337:Drug Carriers / Q000737:chemistry; D016503:Drug Delivery Systems; D004563:Electrochemistry; D006801:Humans; D057139:Nanofibers; D010316:Particle Size; D011108:Polymers / Q000737:chemistry*; D016062:Porosity
chemical_list: D004337:Drug Carriers; D011108:Polymers