title: Therapeutic efficacy of a H₄ receptor antagonist in humans: a milestone in histamine research.
authors.affiliation: Institute of Pharmacology, Hannover Medical School, Hannover, Germany seifert.roland@mh-hannover.de.
authors.forename: Roland
authors.initials: R
authors.lastname: Seifert
mesh_terms: D006632:Histamine / Q000009:adverse effects*; D006633:Histamine Antagonists / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011537:Pruritus / Q000139:chemically induced* / Q000188:drug therapy*; D011743:Pyrimidines / Q000627:therapeutic use*; D011759:Pyrrolidines / Q000627:therapeutic use*; D043562:Receptors, G-Protein-Coupled / Q000037:antagonists & inhibitors*; D011968:Receptors, Histamine; D000074040:Receptors, Histamine H4
chemical_list: C000590929:4-(3-aminopyrrolidin-1-yl)-6-isopropylpyrimidin-2-ylamine; C418607:HRH4 protein, human; D006633:Histamine Antagonists; D011743:Pyrimidines; D011759:Pyrrolidines; D043562:Receptors, G-Protein-Coupled; D011968:Receptors, Histamine; D000074040:Receptors, Histamine H4; D006632:Histamine