title: Clinicopathological findings in a case series of abdominopelvic solitary fibrous tumors.
abstract: Solitary fibrous tumors (SFTs) represent a rare type of soft tissue tumor. Extrathoracic SFTs (ESFTs) in the soft tissues of the abdominopelvic cavity are extremely rare. Between January 2002 and January 2013, 10 patients were identified with abdominopelvic SFTs at the Northern Jiangsu People's Hospital. The clinicopathological data, treatment and follow-up results were retrospectively analyzed in this study. Patients included four females and six males, whose age ranged between 21 and 75 years (mean, 53.3 years). The maximum diameter of the tumors was 2.5-28 cm (mean, 12.7 cm). Two cases were diagnosed as malignant variants of ESFTs. R0resection was performed in eight patients, while one patient underwent R1resection, and one patient received palliative chemotherapy for an inoperable mass. Follow-up time ranged between 6 and 126 months (mean, 50 months). The patient with R1resection suffered a local relapse, and the patient receiving palliative chemotherapy succumbed to the disease. The remaining eight patients remained free of disease. Abdominopelvic SFTs usually reveal an indolent process, although the majority of tumors in the present study were of giant size when diagnosed. The risk of local recurrence and metastasis correlates with tumor size and the histological status of surgical margins. The preferred treatment is complete resection followed by extended follow-up surveillance.
authors.affiliation: Department of Gastrointestinal Surgery, Northern Jiangsu People's Hospital, Yangzhou University, Yangzhou, Jiangsu 225001, P.R. China.
authors.forename: Hao
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Gastrointestinal Surgery, Northern Jiangsu People's Hospital, Yangzhou University, Yangzhou, Jiangsu 225001, P.R. China.
authors.forename: Ping
authors.initials: P
authors.lastname: Chen
authors.affiliation: Department of Gastrointestinal Surgery, Northern Jiangsu People's Hospital, Yangzhou University, Yangzhou, Jiangsu 225001, P.R. China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhao
authors.affiliation: Department of Gastrointestinal Surgery, Northern Jiangsu People's Hospital, Yangzhou University, Yangzhou, Jiangsu 225001, P.R. China.
authors.forename: Lei
authors.initials: L
authors.lastname: Shi
authors.affiliation: Department of Pathology, Northern Jiangsu People's Hospital, Yangzhou University, Yangzhou, Jiangsu 225001, P.R. China.
authors.forename: Xuewen
authors.initials: X
authors.lastname: Gu
authors.affiliation: Department of Pathology, Northern Jiangsu People's Hospital, Yangzhou University, Yangzhou, Jiangsu 225001, P.R. China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Xu
keywords: histopathology; immunohistochemistry; solitary fibrous tumor; spindle cell tumor