title: Chemical constituents and antimicrobial properties of the essential oil and ethanol extract from the stem of Aglaia odorata Lour.
abstract: The stem-derived essential oil of Aglaia odorata Lour. was obtained by hydrodistillation using a Clevenger-type system. Gas chromatography-mass spectrometry analysis of the oil revealed the identification of 39 compounds, representing 76.4% of the oil; germacrene D (20.3%), α-humulene (17.1%), α-himachalene (12.7%) and β-caryophyllene (10.2%) were the major components. Ar-turmerone (1) and eichlerialactone (2) were isolated from the stem oil and ethanolic stem extract of this plant species, respectively. Antimicrobial activities of the oil and ethanol extract were tested against both Gram-positive and Gram-negative bacterial strains including Bacillus cereus ATCC 11778, Staphylococcus aureus ATCC 25923, Acinetobacter baumannii ATCC 19606 and Escherichia coli ATCC 25922, as well as three rice fungal pathogens Bipolaris oryzae, Pyricularia oryzae and Rhizoctonia solani using broth microdilution method. The oil and 1 exhibited significant antifungal activity against the three rice pathogens tested, whereas 2 exhibited good antibacterial activity against both the Gram-positive pathogens tested.
authors.affiliation: a Faculty of Traditional Thai Medicine, Prince of Songkla University , Songkhla 90112 , Thailand.
authors.forename: Nantiya
authors.initials: N
authors.lastname: Joycharat
authors.forename: Sonesay
authors.initials: S
authors.lastname: Thammavong
authors.forename: Supayang Piyawan
authors.initials: SP
authors.lastname: Voravuthikunchai
authors.forename: Patimaporn
authors.initials: P
authors.lastname: Plodpai
authors.forename: Watcharapong
authors.initials: W
authors.lastname: Mitsuwan
authors.forename: Surasak
authors.initials: S
authors.lastname: Limsuwan
authors.forename: Sanan
authors.initials: S
authors.lastname: Subhadhirasakul
mesh_terms: D031602:Aglaia / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D008401:Gas Chromatography-Mass Spectrometry; D006090:Gram-Negative Bacteria / Q000187:drug effects; D007659:Ketones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D000081222:Monocyclic Sesquiterpenes; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*; D012275:Oryza / Q000382:microbiology; D018547:Plant Stems / Q000737:chemistry; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D045788:Sesquiterpenes, Germacrane / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects; D013237:Stereoisomerism
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D007659:Ketones; D000081222:Monocyclic Sesquiterpenes; D009822:Oils, Volatile; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; D045788:Sesquiterpenes, Germacrane; C078098:ar-turmerone; C042686:humulene; C024714:caryophyllene; C412292:himachalene; C027259:germacrene D
keywords: Aglaia odorata; antimicrobial activity; ar-turmerone; essential oil; rice pathogens