title: A pilot study of the association between sleep disturbance in children with liver transplants and parent and family health-related quality of life.
abstract: OBJECTIVE
  To investigate the relationship between sleep disturbance in children with liver transplants and parent and family health-related quality of life (HRQOL).
  
  
  METHODS
  47 parents of children with liver transplants completed measures of child sleep and family HRQOL. Relationships between sleep and HRQOL and differences in HRQOL between groups with scores above and below the cutoff on a pediatric sleep measure were examined.
  
  
  RESULTS
  Parents endorsed higher rates of sleep-related breathing disorder (SRBD) and restless legs syndrome and periodic limb movements during sleep (RLS/PLMS) and lower HRQOL compared with published data. Significant correlations were found between SRBD and RLS/PLMS and HRQOL, and significant group differences in HRQOL were found between groups above and below the cutoff for behavior problems and RLS/PLMS.
  
  
  CONCLUSIONS
  There are significant relationships between symptoms of SRBD and RLS/PLMS in children with liver transplants and family HRQOL. Behavior problems may account for these strong relationships.
authors.affiliation: C.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of MichiganC.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of MichiganC.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of Michigan.
authors.forename: Melissa N
authors.initials: MN
authors.lastname: Andersen
authors.affiliation: C.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of MichiganC.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of MichiganC.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of Michigan.
authors.forename: Dawn
authors.initials: D
authors.lastname: Dore-Stites
authors.affiliation: C.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of MichiganC.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of MichiganC.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of Michigan.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Gleit
authors.affiliation: C.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of MichiganC.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of MichiganC.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of Michigan.
authors.forename: M James
authors.initials: MJ
authors.lastname: Lopez
authors.affiliation: C.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of MichiganC.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of MichiganC.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of Michigan emfred@med.umich.edu.
authors.forename: Emily M
authors.initials: EM
authors.lastname: Fredericks
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005190:Family / Q000523:psychology*; D005260:Female; D006304:Health Status; D006801:Humans; D016031:Liver Transplantation / Q000523:psychology*; D008297:Male; D020189:Nocturnal Myoclonus Syndrome / Q000523:psychology*; D010865:Pilot Projects; D011788:Quality of Life / Q000523:psychology*; D012148:Restless Legs Syndrome / Q000523:psychology*; D012890:Sleep
keywords: behavior problems; organ transplantation; parents; quality of life; sleep