title: Neurodevelopmental outcome in Congenital Diaphragmatic Hernia survivors during the first three years.
abstract: OBJECTIVE
  To determine neurodevelopmental outcome in Congenital Diaphragmatic Hernia (CDH) survivors during the first three years of life.
  
  
  METHODS
  Admitted CDH patients were assessed at the age of 12 (n=18) and 36 months (n=15) using the Bayley Scales of Infant and Toddler Development Third Edition. Neurodevelopmental results of CDH patients were compared with published norms and with a healthy matched control group.
  
  
  RESULTS
  At 12 months, receptive language was mildly delayed in 6% of patients and 6% of patients demonstrated mildly delay in expressive language and gross motor skills. Eighteen percent of CDH patients had severely delayed scores for gross motor skills. At 36 months, expressive language scores were mildly delayed in 21% of patients. When compared to the control group, CDH patients had similar neurodevelopmental scores at 12 and 36 months of age.
  
  
  CONCLUSIONS
  CDH is not necessarily associated with impaired neurodevelopmental outcomes during the first three years of life.
  
  
  CONCLUSIONS
  The aim of this study was to describe neurodevelopmental outcomes in Congenital Diaphragmatic Hernia (CDH) survivors. At 12 months, three (18%) patients had severely delayed scores for gross motor skills. At 36 months, expressive language scores were mildly delayed in three (21%) patients. Neurodevelopmental outcomes of CDH patients were no different to healthy matched controls at 12 and 36 months.
authors.affiliation: Department of Respiratory Medicine, The Children's Hospital at Westmead, Sydney, Australia; Medical School, University of Groningen, Groningen, The Netherlands. Electronic address: l.leeuwen1@gmail.com.
authors.forename: Lisette
authors.initials: L
authors.lastname: Leeuwen
authors.affiliation: Discipline of Paediatrics and Child Health, Sydney Medical School, University of Sydney, Sydney, Australia; Grace Centre for Newborn Care, The Children's Hospital at Westmead, Sydney, Australia.
authors.forename: Karen
authors.initials: K
authors.lastname: Walker
authors.affiliation: Discipline of Paediatrics and Child Health, Sydney Medical School, University of Sydney, Sydney, Australia; Grace Centre for Newborn Care, The Children's Hospital at Westmead, Sydney, Australia.
authors.forename: Robert
authors.initials: R
authors.lastname: Halliday
authors.affiliation: Department of Respiratory Medicine, The Children's Hospital at Westmead, Sydney, Australia; Discipline of Paediatrics and Child Health, Sydney Medical School, University of Sydney, Sydney, Australia.
authors.forename: Dominic A
authors.initials: DA
authors.lastname: Fitzgerald
mesh_terms: D016022:Case-Control Studies; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000209:etiology*; D065630:Hernias, Diaphragmatic, Congenital / Q000150:complications* / Q000401:mortality; D006801:Humans; D007223:Infant; D007805:Language Development Disorders / Q000209:etiology; D008297:Male; D011596:Psychomotor Disorders / Q000209:etiology; D017741:Survivors
keywords: Bayley scales of infant development; Congenital Diaphragmatic Hernia; Neurodevelopmental outcome