title: Impact of chronic kidney disease on quality of life, lung function, and functional capacity.
abstract: OBJECTIVE
  To evaluate the impact of the chronic kidney disease (CKD) on quality of life, from the children's and their parents' perspective, respiratory muscle strength, lung function, and functional capacity in children and adolescents.
  
  
  METHODS
  Cross-sectional study of children with CKD aged 8 to 17 years. Those incapable of taking the tests were excluded. After an interview, quality of life by Pediatric Quality of Life Inventory) (PedsQL(TM)), muscular strength, pulmonary function tests, and the 6-minute walking test (6MWT) were applied. Student's t-test, ANOVA (difference in means), and Pearson's coefficient of correlation were used. The level of significance was set at 5%.
  
  
  RESULTS
  Of the 40 patients, the mean distance walked at the 6MWT was 396 meters, and the mean final score at the quality of life test as perceived by the children and parents was 50.9 and 51, respectively. From the children's perspective, the transplanted patients had a higher quality of life score when compared to those undergoing hemodialysis (p<0.001); those who practiced physical activity had better quality of life when compared to the sedentary children (p<0.001). From the children's and the parents' perspectives, the male gender had a higher quality of life score (p<0.05). There was a positive correlation between the distance walked at the 6MWT and age, height, final PedsQL(TM), forced vital capacity (FVC), and forced expiratory volume in the first second (FEV1), as well as a negative correlation between FEV1/FVC and the distance walked.
  
  
  CONCLUSIONS
  A significant reduction in the quality of life and the functional capacity was observed in children with CKD, influenced by the type of treatment, gender, and sedentary life style.
authors.affiliation: Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, PE, Brazil.
authors.forename: Carolina Guimarães
authors.initials: CG
authors.lastname: Teixeira
authors.affiliation: Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, PE, Brazil.
authors.forename: Maria do Carmo M B
authors.initials: Mdo C
authors.lastname: Duarte
authors.affiliation: Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, PE, Brazil.
authors.forename: Cecília Maciel
authors.initials: CM
authors.lastname: Prado
authors.affiliation: Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, PE, Brazil.
authors.forename: Emídio Cavalcanti de
authors.initials: EC
authors.lastname: Albuquerque
authors.affiliation: Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, PE, Brazil. Electronic address: ftliviabandrade@gmail.com.
authors.forename: Lívia B
authors.initials: LB
authors.lastname: Andrade
mesh_terms: D000293:Adolescent; D000704:Analysis of Variance; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D008297:Male; D009043:Motor Activity / Q000502:physiology; D010290:Parents / Q000523:psychology; D011788:Quality of Life; D051436:Renal Insufficiency, Chronic / Q000150:complications* / Q000503:physiopathology; D012129:Respiratory Function Tests; D012132:Respiratory Muscles / Q000293:injuries*; D057185:Sedentary Behavior; D012737:Sex Factors; D011795:Surveys and Questionnaires; D014477:Underachievement; D016138:Walking / Q000502:physiology
keywords: Child; Criança; Função pulmonar; Insuficiência renal crônica; Pulmonary function test; Qualidade de vida; Quality of life; Renal insufficiency, chronic