title: Evaluation of factors predicting recoverability of renal function after pyeloplasty in adults.
abstract: OBJECTIVE
  To analyze the status of renal function after pyeloplasty in a large contemporary adult series and to detect which variables predict improvement of renal function.
  
  
  METHODS
  85 adult patients were retrospectively identified who had undergone pyeloplasty between January 2002 and May 2011 with available pre- and postoperative diuretic scintigraphy. Preoperative differential renal function (DRF) and single-kidney GFR (SKGFR) were obtained by (99m)Tc-MAG-3 diuretic scintigraphy. Baseline-weighted (bw-) DRF and SKGFR were calculated between baseline conditions and time of last follow-up. Factors that explain the variance of bw-DRF and bw-SKGFR were determined.
  
  
  RESULTS
  The mean (SD) preoperative DRF significantly increased from 34% (11.6) to 37.2% (11.8) after pyeloplasty (p < 0.001). Similarly, mean (SD) SKGFR showed a significant improvement from 31.2 (12.9) to 35.9 (15) ml/min (p < 0.001). Patients with a lower baseline DRF (≤40%) showed a significant improvement as opposed to those with a higher baseline DRF (>40%) (p < 0.001 and 0.3, respectively). Baseline DRF and cortical thickness explained the variance in bw-DRF and bw-SKGFR with more contribution of baseline DRF.
  
  
  CONCLUSIONS
  Renal function showed improvement after pyeloplasty in adults and preoperative DRF and cortical thickness were the predicting variables.
authors.affiliation: Urology and Nephrology Center, Mansoura University, Mansoura, Egypt.
authors.forename: Ahmed M
authors.initials: AM
authors.lastname: Harraz
authors.forename: Diaa-Eldin
authors.initials: DE
authors.lastname: Taha
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Shalaby
authors.forename: Ashraf T
authors.initials: AT
authors.lastname: Hafez
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D020127:Recovery of Function; D012189:Retrospective Studies; D012307:Risk Factors; D015607:Stents; D017263:Technetium Tc 99m Mertiatide; D016896:Treatment Outcome; D014517:Ureteral Obstruction / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D013520:Urologic Surgical Procedures / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D055815:Young Adult
chemical_list: D019275:Radiopharmaceuticals; D017263:Technetium Tc 99m Mertiatide