title: [Assessment of malaria screening management in blood donation control in the French Military Blood Institute].
abstract: The French Military Blood Institute is responsible for the entire blood supply chain in the French Armed Forces. Considering, the high exposition rate of military to malaria risk, blood donation screening of plasmodium infection must be as efficient as possible. The main aim of our study was to assess our malaria testing strategy based on a single Elisa test compared with a two-step strategy implying immunofluorescence testing as confirmation test. The second goal was to describe characteristic of malaria Elisa positive donors. We conducted a prospective study: every malaria Elisa positive test was implemented by immunofluorescence testing and demographical data were recorded as usual by our medical software. We showed a significant risk of malaria ELISA positive tests among donor born in endemic area and we estimate the number of abusively 3-year rejected donors. However, based on our estimations, the two-step strategy is not relevant since the number of additionally collected blood products will be low.
authors.affiliation: Centre de transfusion sanguine des armées, 1, rue du Lieutenant-Batany, 92140 Clamart, France.
authors.forename: T
authors.initials: T
authors.lastname: Pouget
authors.affiliation: Fédération de biologie médicale, hôpital d'instruction des armées Percy, 101, avenue Henri-Barbusse, 92140 Clamart, France.
authors.forename: C
authors.initials: C
authors.lastname: Garcia-Hejl
authors.affiliation: Centre de transfusion sanguine des armées, 1, rue du Lieutenant-Batany, 92140 Clamart, France.
authors.forename: S
authors.initials: S
authors.lastname: Bouzard
authors.affiliation: Centre de transfusion sanguine des armées, 1, rue du Lieutenant-Batany, 92140 Clamart, France.
authors.forename: C
authors.initials: C
authors.lastname: Roche
authors.affiliation: Centre de transfusion sanguine des armées, 1, rue du Lieutenant-Batany, 92140 Clamart, France.
authors.forename: A
authors.initials: A
authors.lastname: Sailliol
authors.affiliation: Fédération de biologie médicale, hôpital d'instruction des armées Percy, 101, avenue Henri-Barbusse, 92140 Clamart, France. Electronic address: christophe.martinaud@inserm.fr.
authors.forename: C
authors.initials: C
authors.lastname: Martinaud
mesh_terms: D000047:Academies and Institutes; D000913:Antibodies, Protozoan / Q000097:blood*; D001771:Blood Banks / Q000191:economics; D001782:Blood Donors / Q000706:statistics & numerical data; D058731:Blood Safety / Q000191:economics / Q000592:standards; D046148:Donor Selection; D019353:Endemic Diseases; D004797:Enzyme-Linked Immunosorbent Assay / Q000191:economics; D019084:Fluorescent Antibody Technique, Indirect / Q000191:economics; D005602:France; D006801:Humans; D008288:Malaria / Q000097:blood / Q000175:diagnosis / Q000517:prevention & control*; D008403:Mass Screening / Q000379:methods*; D008887:Military Medicine; D018512:Parasitemia / Q000175:diagnosis*; D015397:Program Evaluation; D011446:Prospective Studies; D012306:Risk; D000094902:Blood Banking / Q000379:methods*
chemical_list: D000913:Antibodies, Protozoan
keywords: Anti-malaria antibody; Anticorps anti-palustre; Blood donation control; Blood donor; Donneurs de sang; Immunofluorescence; Immunofluorescence testing; Qualification biologique des dons; Serology; Sérologie