title: Validation of a numerical FSI simulation of an aortic BMHV by in vitro PIV experiments.
abstract: In this paper, a validation of a recently developed fluid-structure interaction (FSI) coupling algorithm to simulate numerically the dynamics of an aortic bileaflet mechanical heart valve (BMHV) is performed. This validation is done by comparing the numerical simulation results with in vitro experiments. For the in vitro experiments, the leaflet kinematics and flow fields are obtained via the particle image velocimetry (PIV) technique. Subsequently, the same case is numerically simulated by the coupling algorithm and the resulting leaflet kinematics and flow fields are obtained. Finally, the results are compared, revealing great similarity in leaflet motion and flow fields between the numerical simulation and the experimental test. Therefore, it is concluded that the developed algorithm is able to capture very accurately all the major leaflet kinematics and dynamics and can be used to study and optimize the design of BMHVs.
authors.affiliation: Ghent University, Department of Flow, Heat and Combustion Mechanics, Sint-Pietersnieuwstraat 41, B-9000 Ghent, Belgium. Electronic address: Sebastiaan.Annerel@UGent.be.
authors.forename: S
authors.initials: S
authors.lastname: Annerel
authors.affiliation: Ghent University, Department of Industrial Technology and Construction, Valentin Vaerwyckweg 1, B-9000 Ghent, Belgium. Electronic address: Tom.Claessens@UGent.be.
authors.forename: T
authors.initials: T
authors.lastname: Claessens
authors.affiliation: Ghent University, Department of Flow, Heat and Combustion Mechanics, Sint-Pietersnieuwstraat 41, B-9000 Ghent, Belgium. Electronic address: Joris.Degroote@UGent.be.
authors.forename: J
authors.initials: J
authors.lastname: Degroote
authors.affiliation: Ghent University, iMinds Medical IT, IBiTech-bioMMeda, De Pintelaan 185, B-9000 Ghent, Belgium. Electronic address: Patrick.Segers@UGent.be.
authors.forename: P
authors.initials: P
authors.lastname: Segers
authors.affiliation: Ghent University, Department of Flow, Heat and Combustion Mechanics, Sint-Pietersnieuwstraat 41, B-9000 Ghent, Belgium. Electronic address: Jan.Vierendeels@UGent.be.
authors.forename: J
authors.initials: J
authors.lastname: Vierendeels
mesh_terms: D000465:Algorithms; D001011:Aorta / Q000502:physiology; D001021:Aortic Valve / Q000502:physiology; D001696:Biomechanical Phenomena; D001783:Blood Flow Velocity / Q000502:physiology; D003198:Computer Simulation; D006339:Heart Rate / Q000502:physiology; D006350:Heart Valve Prosthesis; D006801:Humans; D066298:In Vitro Techniques; D008955:Models, Cardiovascular; D012212:Rheology; D013318:Stroke Volume / Q000502:physiology
keywords: BMHV; Experiment; FSI; Numerical simulation; PIV; Validation