title: Microwave assisted synthesis, characterization and biocidal activities of some new chelates of carbazole derived Schiff bases of cadmium and tin metals.
abstract: This study is planned to report the advancement of green microwave approach in the fabrication of a new series of biologically potent (N^X, where X=O/S) donor Schiff bases and their cadmium(II) and tin(II) complexes. The ligands and their metal complexes have been characterized in terms of elemental analysis, molar ionic conductance, magnetic moment and spectral (IR, UV-Vis, NMR ((1)H, (119)Sn), FAB-mass, thermal and XRD) data. The data revealed that the ligands coordinated to the metal center via nitrogen and oxygen/sulfur atoms and form an octahedral arrangement of the ligands around central metal atom. All compounds were evaluated for their in vitro antimicrobial activities against two pathogenic bacteria Bacillus subtilis and Escherichia coli and two fungi Aspergillus niger and Aspergillus flavus by standard disc diffusion method. The discs were stored in an incubator at 37°C. The compounds were dissolved in DMF at 500 and 1000 ppm concentrations for screening biocidal activity. The compounds were dissolved in DMF to get the 100 and 200 ppm concentration of test solutions for screening fungicidal activity. The inhibition zone around each disc was measured (in mm) after 24 h and 96 h for biocidal and fungicidal activities respectively.
authors.affiliation: Department of Chemistry, Banasthali University, Banasthali, Rajasthan 304022, India.
authors.forename: Manju
authors.initials: M
authors.lastname: Yadav
authors.affiliation: Department of Chemistry, Banasthali University, Banasthali, Rajasthan 304022, India.
authors.forename: Neelima
authors.initials: N
authors.lastname: Mishra
authors.affiliation: Department of Chemistry, Banasthali University, Banasthali, Rajasthan 304022, India.
authors.forename: Nutan
authors.initials: N
authors.lastname: Sharma
authors.affiliation: Department of Chemistry, Zakir Husain College, University of Delhi, J.L. Nehru Marg, New Delhi 110002, India.
authors.forename: Sulekh
authors.initials: S
authors.lastname: Chandra
authors.affiliation: Department of Chemistry, Banasthali University, Banasthali, Rajasthan 304022, India. Electronic address: dsbchoudhary2002@gmail.com.
authors.forename: Dinesh
authors.initials: D
authors.lastname: Kumar
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D002104:Cadmium / Q000494:pharmacology*; D002227:Carbazoles / Q000737:chemistry / Q000493:pharmacokinetics*; D002614:Chelating Agents / Q000737:chemistry; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry; D004553:Electric Conductivity; D004583:Electrons; D005658:Fungi / Q000187:drug effects; D008024:Ligands; D060328:Magnetic Phenomena; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D008872:Microwaves; D066244:Proton Magnetic Resonance Spectroscopy; D012545:Schiff Bases / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D013055:Spectrophotometry, Infrared; D013696:Temperature; D014001:Tin / Q000494:pharmacology*; D014961:X-Ray Diffraction
chemical_list: D000890:Anti-Infective Agents; D002227:Carbazoles; D002614:Chelating Agents; D056831:Coordination Complexes; D008024:Ligands; D012545:Schiff Bases; D002104:Cadmium; C041514:carbazole; D014001:Tin
keywords: Antimicrobial activities; Carbazole; Cd(II) and Sn(II) complexes; Schiff bases; Spectral characterization