title: Xeroderma pigmentosum in the United kingdom.
abstract: The seminal discovery by James Cleaver of defective DNA repair in xeroderma pigmentosum (XP) opened up an ever-expanding field of DNA repair-related disorders. In addition, it put XP on the map and has led to improved diagnosis, care and management of affected patients. In the United Kingdom, we recently established a multidisciplinary specialist clinic for XP patients. All XP patients in the United Kingdom are able to visit the clinic where they are examined and advised by a team of specialists with detailed knowledge of the different aspects of XP.
authors.affiliation: Genome Damage and Stability Centre, University of Sussex, Falmer, Brighton, BN1 9RQ, UK.
authors.forename: Alan R
authors.initials: AR
authors.lastname: Lehmann
mesh_terms: D017668:Age of Onset; D004249:DNA Damage; D004260:DNA Repair; D004273:DNA, Neoplasm / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D008545:Melanoma / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000235:genetics; D012867:Skin / Q000378:metabolism / Q000473:pathology / Q000528:radiation effects; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000235:genetics; D012880:Skin Pigmentation / Q000528:radiation effects; D014466:Ultraviolet Rays / Q000009:adverse effects; D006113:United Kingdom / Q000453:epidemiology; D014983:Xeroderma Pigmentosum / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000235:genetics
chemical_list: D004273:DNA, Neoplasm