title: Technical Note: evaluation of the uncertainties in (choline + creatine)/citrate ratios measured by proton MR spectroscopic imaging in patients suspicious for prostate cancer.
abstract: The presented evaluation of the relative uncertainty (δ'CCC) of the (choline + creatine)/citrate (CC/C) ratios can provide objective information about the quality and diagnostic value of prostate MR spectroscopic imaging data. This information can be combined with the numeric values of CC/C ratios and provides metabolic-quality maps enabling accurate cancer detection and user-independent data evaluation. In addition, the prostate areas suffering most from the low precision of CC/C ratios (e. g., prostate base) were identified.
authors.forename: Š
authors.initials: Š
authors.lastname: Zbýň
authors.forename: M
authors.initials: M
authors.lastname: Krššák
authors.forename: M
authors.initials: M
authors.lastname: Memarsadeghi
authors.forename: B
authors.initials: B
authors.lastname: Gholami
authors.forename: A
authors.initials: A
authors.lastname: Haitel
authors.forename: M
authors.initials: M
authors.lastname: Weber
authors.forename: T H
authors.initials: TH
authors.lastname: Helbich
authors.forename: S
authors.initials: S
authors.lastname: Trattnig
authors.forename: E
authors.initials: E
authors.lastname: Moser
authors.forename: S
authors.initials: S
authors.lastname: Gruber
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D014408:Biomarkers, Tumor / Q000378:metabolism*; D002794:Choline / Q000378:metabolism*; D019343:Citric Acid / Q000378:metabolism*; D003401:Creatine / Q000378:metabolism*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000378:metabolism*; D011522:Protons; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D014408:Biomarkers, Tumor; D011522:Protons; D019343:Citric Acid; D003401:Creatine; D002794:Choline