title: Intractable prurigo nodularis successfully treated with combination therapy with a newly developed excimer laser and topical steroids.
abstract: Prurigo nodularis (PN) is an eruption of lichenified or excoriated nodules related to intractable pruritus. A few reports have shown that a 308-nm excimer lamp/laser (EL) is effective for intractable PN. Herein, we report on two cases of intractable prurigo nodularis successfully treated with a new EL equipped with a filter to cut wavelengths shorter than 297 nm. Because this newly developed EL yields a therapeutic effect with low cumulative dosages of UV and a lower risk of DNA damage, it can be a new treatment option for intractable PN.
authors.forename: Chisa
authors.initials: C
authors.lastname: Nakashima
authors.forename: Hideaki
authors.initials: H
authors.lastname: Tanizaki
authors.forename: Atsushi
authors.initials: A
authors.lastname: Otsuka
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Miyachi
authors.affiliation: Kyoto University Graduate School of Medicine, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Kabashima
mesh_terms: D000284:Administration, Oral; D000287:Administration, Topical; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000328:Adult; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D011536:Prurigo / Q000188:drug therapy* / Q000601:surgery*
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents