title: [Ovarian stimulation with gonadotropins: comparison between recombinant FSH plus menotropins versus recombinant FSH + LH].
abstract: BACKGROUND
  Nowadays various assisted reproduction ovarian stimulation schemes are used for different clinical outcomes is interesting to compare.
  
  
  OBJECTIVE
  Compare two ovarian stimulation protocols: recombinant FSH + LH versus recombinant FSH + Menotropins.
  
  
  METHODS
  Observational, retrospective study, 38 cycles were analyzed, made from 2010 until 2013, assigned to two groups (n = 19 each), group 1 received FSHr + LHr, group 2 received FSHr + menotropins. Study variables were: days of ovarian stimulation, total gonadotropin dose, retrieved oocytes, fertilization rate, pregnancy rate and number of vitrified embryos.
  
  
  RESULTS
  Fewer stimulation days (8.5 +/- 1.5 vs 9 +/- 1.1) were found in group 1 (recombinant gonadotropins). Group 2 (FSHr + Menotropins), had a greater total dose of gonadotropins (1930.2 +/- 346.2 vs 2000 +/- 418.8) and more retrieved oocytes (8.15 +/- 3.9 vs 8.57 +/- 4). Group 1 patients had higher pregnancy and fertilization rates (56.2 vs 36.8%, and 75.4 vs 69.3%) respectively, no statistical significance was found.
  
  
  CONCLUSIONS
  This study found higher pregnancy and fertilization rates in patients treated with recombinant gonadotropins (FSH + LH) for ovarian stimulation.
authors.forename: Alvaro
authors.initials: A
authors.lastname: Santibáñez Morales
authors.forename: Edgar Omar
authors.initials: EO
authors.lastname: Colín Licea
authors.forename: Esteban
authors.initials: E
authors.lastname: Durán Boullosa
authors.forename: Paola
authors.initials: P
authors.lastname: Sánchez Serrano
authors.forename: Olga
authors.initials: O
authors.lastname: Pashkova
mesh_terms: D000328:Adult; D004359:Drug Therapy, Combination; D005260:Female; D043373:Follicle Stimulating Hormone, Human / Q000008:administration & dosage*; D006062:Gonadotropins / Q000008:administration & dosage*; D006801:Humans; D007986:Luteinizing Hormone / Q000008:administration & dosage*; D008596:Menotropins / Q000008:administration & dosage*; D010062:Ovulation Induction / Q000379:methods*; D011994:Recombinant Proteins / Q000008:administration & dosage; D012189:Retrospective Studies
chemical_list: D043373:Follicle Stimulating Hormone, Human; D006062:Gonadotropins; D011994:Recombinant Proteins; D008596:Menotropins; D007986:Luteinizing Hormone