title: ESHRE task force on ethics and Law22: preimplantation genetic diagnosis.
abstract: This Task Force document discusses some relatively unexplored ethical issues involved in preimplantation genetic diagnosis (PGD). The document starts from the wide consensus that PGD is ethically acceptable if aimed at helping at-risk couples to avoid having a child with a serious disorder. However, if understood as a limit to acceptable indications for PGD, this 'medical model' may turn out too restrictive. The document discusses a range of possible requests for PGD that for different reasons fall outwith the accepted model and argues that instead of rejecting those requests out of hand, they need to be independently assessed in the light of ethical criteria. Whereas, for instance, there is no good reason for rejecting PGD in order to avoid health problems in a third generation (where the second generation would be healthy but faced with burdensome reproductive choices if wanting to have children), using PGD to make sure that one's child will have the same disorder or handicap as its parents, is ethically unacceptable.
authors.affiliation: Department of Health, Ethics & Society, Research Institutes CAPHRI and GROW, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands g.dewert@maastrichtuniversity.nl.
authors.forename: G
authors.initials: G
authors.lastname: De Wert
authors.affiliation: Department of Health, Ethics & Society, Research Institutes CAPHRI and GROW, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands.
authors.forename: W
authors.initials: W
authors.lastname: Dondorp
authors.affiliation: Reproductive Medicine Unit, Obstetric Hospital, 2nd Floor, University College Hospital Huntley Street, London WC1 6AU, UK.
authors.forename: F
authors.initials: F
authors.lastname: Shenfield
authors.affiliation: Centre for Reproductive Medicine, UZ Brussel, Brussels, Belgium.
authors.forename: P
authors.initials: P
authors.lastname: Devroey
authors.affiliation: Infertility and IVF Center, Department of OB/GYN Medical School, Aristotle University of Thessaloniki, Greece.
authors.forename: B
authors.initials: B
authors.lastname: Tarlatzis
authors.affiliation: Servei de Medicina de la Reproducció, Departament d'Obstetricia, Universitari Dexeus, Ginecologia i Reproducció, Barcelona, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Barri
authors.affiliation: Department of Obstetrics and Gynaecology, University of Luebeck, Ratzeburger Allee 160, D-23538 Luebeck, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Diedrich
authors.affiliation: Department of Philosophy, University of Ghent, Blandijnberg 2, Gent 9000, Belgium.
authors.forename: V
authors.initials: V
authors.lastname: Provoost
authors.affiliation: Department of Philosophy, University of Ghent, Blandijnberg 2, Gent 9000, Belgium.
authors.forename: G
authors.initials: G
authors.lastname: Pennings
mesh_terms: D026683:Advisory Committees; D004624:Embryo Transfer / Q000941:ethics; D005307:Fertilization in Vitro / Q000941:ethics* / Q000331:legislation & jurisprudence; D030342:Genetic Diseases, Inborn / Q000517:prevention & control*; D006801:Humans; D026684:Personal Autonomy; D019836:Preimplantation Diagnosis / Q000941:ethics*; D018570:Risk Assessment; D012743:Sex Preselection / Q000941:ethics
keywords: PGD; ethics; indications; transfer decisions