title: Visualization of upconverting nanoparticles in strongly scattering media.
abstract: Optical visualization systems are needed in medical applications for determining the localization of deep-seated luminescent markers in biotissues. The spatial resolution of such systems is limited by the scattering of the tissues. We present a novel epi-luminescent technique, which allows a 1.8-fold increase in the lateral spatial resolution in determining the localization of markers lying deep in a scattering medium compared to the traditional visualization techniques. This goal is attained by using NaYF4:Yb(3+)Tm(3+)@NaYF4 core/shell nanoparticles and special optical fiber probe with combined channels for the excitation and detection of anti-Stokes luminescence signals.
authors.affiliation: Institute on Laser and Information Technologies of the Russian Academy of Sciences, City of Shatura, Moscow Region, Svyatoozerskaya ul. 1, 140700, Russia.
authors.forename: E V
authors.initials: EV
authors.lastname: Khaydukov
authors.affiliation: Institute on Laser and Information Technologies of the Russian Academy of Sciences, City of Shatura, Moscow Region, Svyatoozerskaya ul. 1, 140700, Russia.
authors.forename: V A
authors.initials: VA
authors.lastname: Semchishen
authors.affiliation: Institute on Laser and Information Technologies of the Russian Academy of Sciences, City of Shatura, Moscow Region, Svyatoozerskaya ul. 1, 140700, Russia.
authors.forename: V N
authors.initials: VN
authors.lastname: Seminogov
authors.affiliation: Institute on Laser and Information Technologies of the Russian Academy of Sciences, City of Shatura, Moscow Region, Svyatoozerskaya ul. 1, 140700, Russia ; M.V. Lomonosov Moscow State University of Fine Chemical Technologies, Moscow, prospekt Vernadskogo 86, 119541, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Nechaev
authors.affiliation: Institute on Laser and Information Technologies of the Russian Academy of Sciences, City of Shatura, Moscow Region, Svyatoozerskaya ul. 1, 140700, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Zvyagin
authors.affiliation: Institute on Laser and Information Technologies of the Russian Academy of Sciences, City of Shatura, Moscow Region, Svyatoozerskaya ul. 1, 140700, Russia.
authors.forename: V I
authors.initials: VI
authors.lastname: Sokolov
authors.affiliation: Institute on Laser and Information Technologies of the Russian Academy of Sciences, City of Shatura, Moscow Region, Svyatoozerskaya ul. 1, 140700, Russia.
authors.forename: A S
authors.initials: AS
authors.lastname: Akhmanov
authors.affiliation: Institute on Laser and Information Technologies of the Russian Academy of Sciences, City of Shatura, Moscow Region, Svyatoozerskaya ul. 1, 140700, Russia.
authors.forename: V Ya
authors.initials: VY
authors.lastname: Panchenko
keywords: (110.0113) Imaging through turbid media; (160.4236) Nanomaterials