title: Anti-graying effect of the extract of Pueraria thunbergiana via upregulation of cAMP/MITF-M signaling pathway.
authors.affiliation: Department of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea; Laboratory of Cutaneous Aging Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea; Institute of Human-Environmental Interface Biology, Seoul National University College of Medicine, Seoul, Republic of Korea.
authors.forename: Won-Seok
authors.initials: WS
authors.lastname: Park
authors.affiliation: Department of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea; Laboratory of Cutaneous Aging Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea; Institute of Human-Environmental Interface Biology, Seoul National University College of Medicine, Seoul, Republic of Korea.
authors.forename: Ohsang
authors.initials: O
authors.lastname: Kwon
authors.affiliation: Department of Dermatology and Institute of Health Sciences, School of Medicine, Gyeongsang National University Hospital, Jinju, Republic of Korea.
authors.forename: Tae-Jin
authors.initials: TJ
authors.lastname: Yoon
authors.affiliation: Department of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea; Laboratory of Cutaneous Aging Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea; Institute of Human-Environmental Interface Biology, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address: jhchung@snu.ac.kr.
authors.forename: Jin Ho
authors.initials: JH
authors.lastname: Chung
mesh_terms: D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D006197:Hair / Q000187:drug effects* / Q000378:metabolism; D006200:Hair Color / Q000187:drug effects*; D007529:Isoflavones / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects / Q000378:metabolism; D008543:Melanins / Q000378:metabolism; D051379:Mice; D018345:Mice, Knockout; D051739:Microphthalmia-Associated Transcription Factor / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*; D010936:Plant Extracts / Q000494:pharmacology*; D029908:Pueraria; D015398:Signal Transduction / Q000187:drug effects*; D013997:Time Factors; D015027:Zebrafish / Q000196:embryology / Q000378:metabolism
chemical_list: D007529:Isoflavones; D008543:Melanins; D051739:Microphthalmia-Associated Transcription Factor; C497235:Mitf protein, mouse; D010936:Plant Extracts; D000242:Cyclic AMP; C033607:puerarin
keywords: Hair graying; MITF; Melanogenesis; Puerariathunbergiana