title: Effects of carbohydrate counting method on metabolic control in children with type 1 diabetes mellitus.
abstract: Medical nutritional therapy is important for glycemic control in children and adolescents with type 1 diabetes mellitus (T1DM). Carbohydrate (carb) counting, which is a more flexible nutritional method, has become popular in recent years. This study aimed to investigate the effects of carb counting on metabolic control, body measurements and serum lipid levels in children and adolescents with T1DM.
  
  
  
  T1DM patients aged 7-18 years and receiving flexible insulin therapy were divided into carb counting (n=52) and control (n=32) groups and were followed for 2 years in this randomized, controlled study. Demographic characteristics, body measurements, insulin requirements, hemoglobin A1c (HbA1c) and serum lipid levels at baseline and at follow-up were evaluated.
  
  
  
  There were no statistically significant differences between the groups in mean HbA1c values in the year preceding the study or in age, gender, duration of diabetes, puberty stage, total daily insulin dose, body mass index (BMI) standard deviation score (SDS) and serum lipid values. While there were no differences in BMI SDS, daily insulin requirement, total cholesterol, low-density lipoprotein and triglyceride values between the two groups (p>0.05) during the follow-up, annual mean HbA1c levels of the 2nd year were significantly lower in the carb counting group (p=0.010). The mean values of high-density lipoprotein were also significantly higher in the first and 2nd years in the carb counting group (p=0.02 and p=0.043, respectively).
  
  
  
  Carb counting may provide good metabolic control in children and adolescents with T1DM without causing any increase in weight or in insulin requirements.
authors.affiliation: Ege University School of Medicine, Department of Pediatric Endocrinology, İzmir, Turkey. E-ma-il: yaseminatik@yahoo.com.tr.
authors.forename: Damla
authors.initials: D
authors.lastname: Gökşen
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Atik Altınok
authors.forename: Samim
authors.initials: S
authors.lastname: Ozen
authors.forename: Günay
authors.initials: G
authors.lastname: Demir
authors.forename: Sükran
authors.initials: S
authors.lastname: Darcan
mesh_terms: D000293:Adolescent; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000178:diet therapy* / Q000188:drug therapy / Q000378:metabolism; D003927:Diet, Diabetic; D004040:Dietary Carbohydrates / Q000032:analysis* / Q000378:metabolism; D006442:Glycated Hemoglobin / Q000378:metabolism; D038321:Glycemic Index; D006801:Humans; D007328:Insulin / Q000008:administration & dosage; D008055:Lipids / Q000097:blood
chemical_list: D004040:Dietary Carbohydrates; D006442:Glycated Hemoglobin; D007328:Insulin; D008055:Lipids; C517652:hemoglobin A1c protein, human