title: Bisphosphonate-induced osteonecrosis of the maxilla presenting as a cicatricial ectropion.
abstract: A 63-year-old gentleman, who was being treated with bisphosphonates for multiple myeloma, presented with a cicatricial ectropion of the lower eyelid, without exposure keratopathy. A CT scan demonstrated extensive destruction of bone with an infraorbital fracture surrounded by sclerotic bony changes. The patient was managed conservatively with discontinuation of bisphosphonate therapy and topical ocular lubricants. The patient's condition remained unchanged a year after this initial management.
authors.affiliation: Manchester Royal Eye Hospital, Oculoplastic Unit , Manchester , United Kingdom .
authors.forename: Rizwan
authors.initials: R
authors.lastname: Malik
authors.forename: Bertie S
authors.initials: BS
authors.lastname: Fernando
authors.forename: Roger D
authors.initials: RD
authors.lastname: Laitt
authors.forename: Brian
authors.initials: B
authors.lastname: Leatherbarrow
mesh_terms: D050071:Bone Density Conservation Agents / Q000009:adverse effects*; D004164:Diphosphonates / Q000009:adverse effects*; D004483:Ectropion / Q000139:chemically induced* / Q000175:diagnosis; D005143:Eyelids / Q000473:pathology; D006801:Humans; D008297:Male; D008439:Maxillary Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging; D008875:Middle Aged; D009101:Multiple Myeloma / Q000188:drug therapy; D010020:Osteonecrosis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates
keywords: Bisphosphonate; ectropion; osteonecrosis