title: Syndrome in question.
abstract: A 48-year-old male patient with chronic alcoholism presented with a soft, bulky, asymptomatic, and slow-growing mass in the posterior region of the neck, as well as nodules in the deltoid region and posterior triangle of the sternocleidomastoid muscle. Needle aspiration confirmed the diagnosis of lipoma. Multiple symmetric lipomatosis (Madelung's disease) is a rare proliferation of adipocytes, of unknown etiology, most common in middle-aged men and mainly associated with alcoholism. It predominantly affects the neck and upper trunk, causing compressive symptoms or a imparting a pseudoathletic appearance. Surgical resection or liposuction is the most effective treatment, despite frequent recurrence.
authors.affiliation: Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu, SP, Brazil.
authors.forename: Cínthia Rosane
authors.initials: CR
authors.lastname: Orasmo
authors.affiliation: Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu, SP, Brazil.
authors.forename: Juliana Polizel
authors.initials: JP
authors.lastname: Ocanha
authors.affiliation: Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu, SP, Brazil.
authors.forename: Silvia Regina Catharino
authors.initials: SR
authors.lastname: Barraviera
authors.affiliation: Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu, SP, Brazil.
authors.forename: Hélio Amante
authors.initials: HA
authors.lastname: Miot
mesh_terms: D000437:Alcoholism / Q000150:complications*; D001707:Biopsy, Needle; D006801:Humans; D008067:Lipoma / Q000000981:diagnostic imaging / Q000473:pathology*; D008069:Lipomatosis, Multiple Symmetrical / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D013577:Syndrome; D014057:Tomography, X-Ray Computed