title: Prevalence of IgE mediated cow's milk and egg allergy in children under 2 years of age in Sanliurfa, Turkey: the city that isn't almost allergic to cow's milk.
abstract: OBJECTIVE
  Food allergy is a common problem in children and adults. The aim of this study was to determine the frequency of cow's milk and egg allergy based on skin prick test and oral food challenge results
  
  
  METHODS
  We recruited 614 children aged 1 month-2 years in from different areas of Sanliurfa. An interview was conducted with each parents and family demographic, and prenatal-antenatal-postnatal information was recorded, then skin prick test was applied to the children for egg white, egg yolk and cow's milk. Cases that are required, sIgE levels for cow's milk, egg white and egg yolk were measured and food challenge tests were applied.
  
  
  RESULTS
  Cow's milk and egg allergy was determined in 1 case (0.16%) and 8 cases (1.30%) respectively from the results of the tests applied. Six cases (0.97%) were accepted as sensitive to egg white and egg yolk. Within the factors which were questioned, (only the egg allergy evaluation was made without the cow's milk allergy case) of those with parental consanguinity was determined at a statistically significantly high level (OR=5.8, 95% CI: 1.2-27.2, P=0.01).
  
  
  CONCLUSIONS
  The prevalence of cow's milk allergy in Sanliurfa is the lowest reported prevalence rate to date in children under 2 years of age. When infants develop a food allergy, this takes the form of egg allergy. Within the several factors evaluated to explain this situation, a significant relationship was determined only with parental consanguinity. However, as reported above, to date there is no genetic or epidemiological study to explain this situation.
authors.affiliation: Division of Allergy and Immunology, Department of Pediatrics, Harran University School of Medicine Sanliurfa, Turkey - dostzeyrek@yahoo.com.
authors.forename: D
authors.initials: D
authors.lastname: Zeyrek
authors.forename: I
authors.initials: I
authors.lastname: Koruk
authors.forename: B
authors.initials: B
authors.lastname: Kara
authors.forename: C
authors.initials: C
authors.lastname: Demir
authors.forename: A
authors.initials: A
authors.lastname: Cakmak
mesh_terms: D002675:Child, Preschool; D021181:Egg Hypersensitivity / Q000453:epidemiology* / Q000276:immunology; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D007223:Infant; D008297:Male; D016269:Milk Hypersensitivity / Q000453:epidemiology* / Q000276:immunology; D010865:Pilot Projects; D015995:Prevalence; D012882:Skin Tests; D014421:Turkey / Q000453:epidemiology
chemical_list: D007073:Immunoglobulin E