title: Casting a wide net for endocrine disruptors.
abstract: The number of chemicals identified as endocrine disruptors continues to rise, and, yet, many assays intended to prioritize them for further action cannot gauge their impact on cells. Stossi and colleagues present new high-throughput screening methods that inform estrogen receptor biology, leading to questions about "safe alternatives" for one compound, bisphenol A.
authors.affiliation: Division of Environmental Health Sciences, School of Public Health, University of Massachusetts-Amherst, 149B Goessmann, 686 N. Pleasant Street, Amherst, MA 01003, USA; Program in Neuroscience and Behavior, University of Massachusetts-Amherst, 221 Morrill Science Center, 611 N. Pleasant Street, Amherst, MA 01003, USA. Electronic address: lvandenberg@schoolph.umass.edu.
authors.forename: Laura N
authors.initials: LN
authors.lastname: Vandenberg
authors.affiliation: Program in Neuroscience and Behavior, University of Massachusetts-Amherst, 221 Morrill Science Center, 611 N. Pleasant Street, Amherst, MA 01003, USA.
authors.forename: Mary C
authors.initials: MC
authors.lastname: Catanese
mesh_terms: D001559:Benzhydryl Compounds / Q000737:chemistry* / Q000494:pharmacology*; D047628:Estrogen Receptor alpha / Q000819:agonists*; D047629:Estrogen Receptor beta / Q000037:antagonists & inhibitors*; D057166:High-Throughput Screening Assays; D006801:Humans; D010636:Phenols / Q000737:chemistry* / Q000494:pharmacology*; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D047628:Estrogen Receptor alpha; D047629:Estrogen Receptor beta; D010636:Phenols; C006780:bisphenol A; D000098826:Bisphenol A Compounds