title: Sugar-based molecular computing by material implication.
abstract: A method to integrate an (in principle) unlimited number of molecular logic gates to construct complex circuits is presented. Logic circuits, such as half- or full-adders, can be reinterpreted by using the functional completeness of the implication function (IMP) and the trivial FALSE operation. The molecular gate IMP is represented by a fluorescent boronic acid sugar probe. An external wiring algorithm translates the fluorescent output from one gate into a chemical input for the next gate on microtiter plates. This process is demonstrated on a four-bit full adder.
authors.affiliation: Institute for Inorganic and Analytical Chemistry & Abbe Center of Photonics (ACP), Friedrich Schiller University Jena, Humboldtstrasse 8, 07743 Jena (Germany).
authors.forename: Martin
authors.initials: M
authors.lastname: Elstner
authors.forename: Jörg
authors.initials: J
authors.lastname: Axthelm
authors.forename: Alexander
authors.initials: A
authors.lastname: Schiller
keywords: fluorescence; logic gates; molecular computing; sugar sensors