title: Unambiguous Assignment of Reduction Potentials in Diheme Cytochromes.
abstract: Perturbed matrix method calculations are performed on a diheme cytochrome c (DHC) protein, in order to assign previously experimentally detemined reduction potentials (E0) to their corresponding heme groups. Very good agreement between calculated values to experimental data prove that the present approach can be used as a predictive tool of redox thermodynamic properties of multicenter redox proteins in the absence of experimental data, or in synergy with state-of-the art spectroscopic and electrochemical approaches to obtain a detailed picture of electron transfer processes within these complex systems.
authors.affiliation: Department of Physical and Chemical Sciences, University of L'Aquila , via Vetoio (Coppito 1), 67010 L'Aquila, Italy.
authors.forename: Isabella
authors.initials: I
authors.lastname: Daidone
authors.affiliation: Department of Chemical and Geological Sciences, University of Modena and Reggio Emilia , via Campi 183, 41125 Modena, Italy.
authors.forename: Licia
authors.initials: L
authors.lastname: Paltrinieri
authors.affiliation: Department of Chemical Sciences and Technologies, University of Rome "Tor Vergata" , via della Ricerca Scientifica 1, 00133 Rome, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Amadei
authors.affiliation: Department of Chemical and Geological Sciences, University of Modena and Reggio Emilia , via Campi 183, 41125 Modena, Italy.
authors.forename: Gianantonio
authors.initials: G
authors.lastname: Battistuzzi
authors.affiliation: Department of Life Sciences, University of Modena and Reggio Emilia , via Campi 183, 41125 Modena, Italy.|CNR-Nano Institute of Nanoscience, via Campi 213/A, 41125 Modena, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Sola
authors.affiliation: Department of Chemical and Geological Sciences, University of Modena and Reggio Emilia , via Campi 183, 41125 Modena, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Borsari
authors.affiliation: Department of Life Sciences, University of Modena and Reggio Emilia , via Campi 183, 41125 Modena, Italy.|CNR-Nano Institute of Nanoscience, via Campi 213/A, 41125 Modena, Italy.
authors.forename: Carlo Augusto
authors.initials: CA
authors.lastname: Bortolotti