title: Diagnosis and treatment of tuberculosis among children at an HIV care program in Dar es Salaam, Tanzania.
abstract: Diagnosis and treatment of tuberculosis is challenging in children with human immunodeficiency virus (HIV) infection. We describe the clinical features, diagnostic testing results, tuberculosis and HIV treatment and clinical outcomes of 57 HIV-infected children diagnosed with tuberculosis at the DarDar Pediatric Program in Dar es Salaam, Tanzania. In this cohort, tuberculosis was common, microbiologic studies were frequently negative and mortality was high.
authors.affiliation: From the *Infectious Disease and International Health Section, Geisel School of Medicine at Dartmouth; †Dartmouth College, Hanover, NH; ‡Muhimbili University of Health and Allied Sciences; §Management and Development for Health, Dar es Salaam, Tanzania; Departments of ¶Medicine and ‖Pediatrics, University of California at San Francisco, San Francisco, CA; and **DarDar Pediatric Program, Dar es Salaam, Tanzania.
authors.forename: Lisa V
authors.initials: LV
authors.lastname: Adams
authors.forename: Thomas
authors.initials: T
authors.lastname: McQuillan
authors.forename: Helga E
authors.initials: HE
authors.lastname: Naburi
authors.forename: Goodluck
authors.initials: G
authors.lastname: Lyatuu
authors.forename: Matthew M
authors.initials: MM
authors.lastname: Ippolito
authors.forename: Andrew
authors.initials: A
authors.lastname: Saunders
authors.forename: Anna
authors.initials: A
authors.lastname: Kiravu
authors.forename: Paul
authors.initials: P
authors.lastname: Palumbo
authors.forename: C Fordham
authors.initials: CF
authors.lastname: von Reyn
mesh_terms: D000293:Adolescent; D000995:Antitubercular Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003955:Diagnostic Tests, Routine / Q000379:methods; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007223:Infant; D008297:Male; D016019:Survival Analysis; D013636:Tanzania; D016896:Treatment Outcome; D014376:Tuberculosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000995:Antitubercular Agents