title: Immunological disbalance in carcinogenesis.
abstract: It is postulated a conception of immunological disbalance between carcinogenesis inhibiting and stimulating antibodies (Ab). Inhibiting Ab prevent the carcinogens and estradiol but increase the progesterone penetration into the target cells. And vise versa do stimulating Ab. Inhibiting Ab could be blocked by corresponding antiidiotypic Ab. The processes of carcinogenesis initiation and promotion are intensified when stimulating Ab prevail over inhibiting ones.
authors.affiliation: Institute of Human Ecology of Siberian Branch of Russian Academy of Sciences, Kemerovo, Russia. Electronic address: glushkovan@ihe.sbras.ru.
authors.forename: Andrey N
authors.initials: AN
authors.lastname: Glushkov
mesh_terms: D000912:Antibodies, Neoplasm / Q000276:immunology* / Q000378:metabolism; D063646:Carcinogenesis / Q000276:immunology*; D002274:Carcinogens, Environmental / Q000378:metabolism*; D006801:Humans; D018448:Models, Immunological
chemical_list: D000912:Antibodies, Neoplasm; D002274:Carcinogens, Environmental