title: Rubella Virus-associated Anterior Uveitis in a Vaccinated Patient: A Case Report.
abstract: Rubella virus is involved in the pathogenesis of Fuchs heterochromic uveitis and almost all cases in Europe show an active antibody production in the aqueous humor against rubella virus. Herein we report a case of a fully vaccinated patient with common variable immunodeficiency who developed unilateral Fuchs heterochromic uveitis secondary to rubella virus which was proven by intraocular fluid examination. Awareness of rubella associated anterior uveitis should remain also in vaccinated patients, especially those without a fully competent immune system.
authors.affiliation: a Department of Ophthalmology , Erasmus MC, University Medical Center Rotterdam , Rotterdam , The Netherlands , and.
authors.forename: Josianne C E M
authors.initials: JC
authors.lastname: ten Berge
authors.affiliation: b Department of Immunology, Erasmus MC , University Medical Center Rotterdam , Rotterdam , The Netherlands.
authors.forename: Paul L A
authors.initials: PL
authors.lastname: van Daele
authors.affiliation: a Department of Ophthalmology , Erasmus MC, University Medical Center Rotterdam , Rotterdam , The Netherlands , and.
authors.forename: Aniki
authors.initials: A
authors.lastname: Rothova
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D001082:Aqueous Humor / Q000276:immunology / Q000821:virology; D017074:Common Variable Immunodeficiency / Q000175:diagnosis / Q000628:therapy; D015828:Eye Infections, Viral / Q000175:diagnosis / Q000821:virology*; D006801:Humans; D015863:Iridocyclitis / Q000175:diagnosis / Q000821:virology*; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis / Q000532:radiotherapy; D008297:Male; D012409:Rubella / Q000175:diagnosis / Q000821:virology*; D012411:Rubella Vaccine / Q000008:administration & dosage*; D012412:Rubella virus / Q000302:isolation & purification*; D014611:Vaccination
chemical_list: D000914:Antibodies, Viral; D012411:Rubella Vaccine
keywords: Fuchs heterochromic uveitis; immunocompromised; rubella virus; uveitis anterior; vaccination