title: Rhodium(III)-catalyzed cross-coupling of alkenylboronic acids and N-pivaloyloxylamides.
abstract: Rh(III)-catalyzed umpolung amidation of alkenylboronic acids for the synthesis of enamides is reported. This reaction proceeds readily at room temperature and displays an extremely wide spectrum of functional group tolerance. With cooperation of hydroboration, it enables the formal anti-Markovnikov hydroamidation of terminal alkynes, stereospecifically affording the trans-enamides in excellent yields.
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University , Singapore 637371.
authors.forename: Chao
authors.initials: C
authors.lastname: Feng
authors.forename: Teck-Peng
authors.initials: TP
authors.lastname: Loh