title: Canarypox virus expressing infectious bursal disease VP2 protein as immunogen for chickens.
abstract: Canarypox viruses (CNPV) carrying the coding sequence of VP2 protein from infectious bursal disease virus (IBDV) were obtained. These viruses were able to express VP2 protein in vitro and to induce IBDV-neutralizing antibodies when inoculated in specific pathogen-free chickens demonstrating that CNPV platform is usefulness to develop immunogens for chickens.
authors.affiliation: Consejo Nacional de Investigaciones Científicas y Tecnológicas Ciudad Autónoma de Buenos Aires Argentina.
authors.forename: Flavia Adriana
authors.initials: FA
authors.lastname: Zanetti
authors.affiliation: Consejo Nacional de Investigaciones Científicas y Tecnológicas Ciudad Autónoma de Buenos Aires Argentina.
authors.forename: María Daniela Conte
authors.initials: MD
authors.lastname: Grand
authors.affiliation: Instituto de Biotecnología Centro de Investigaciones en Ciencias Veterinarias y Agronómicas Instituto Nacional de Tecnología Agropecuaria Castelar, Buenos Aires Argentina.
authors.forename: Romina Cristina
authors.initials: RC
authors.lastname: Mitarotonda
authors.affiliation: Consejo Nacional de Investigaciones Científicas y Tecnológicas Ciudad Autónoma de Buenos Aires Argentina ; Instituto de Biotecnología Centro de Investigaciones en Ciencias Veterinarias y Agronómicas Instituto Nacional de Tecnología Agropecuaria Castelar, Buenos Aires Argentina.
authors.forename: Oscar Alberto
authors.initials: OA
authors.lastname: Taboga
authors.affiliation: Instituto de Biotecnología Centro de Investigaciones en Ciencias Veterinarias y Agronómicas Instituto Nacional de Tecnología Agropecuaria Castelar, Buenos Aires Argentina.
authors.forename: Gabriela
authors.initials: G
authors.lastname: Calamante
mesh_terms: D000818:Animals; D057134:Antibodies, Neutralizing / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood; D018175:Birnaviridae Infections / Q000276:immunology / Q000517:prevention & control / Q000662:veterinary*; D028121:Canarypox virus / Q000235:genetics*; D002645:Chickens; D004337:Drug Carriers; D005822:Genetic Vectors; D011201:Poultry Diseases / Q000276:immunology / Q000517:prevention & control*; D011994:Recombinant Proteins / Q000235:genetics / Q000276:immunology; D014614:Vaccines, Synthetic / Q000008:administration & dosage / Q000235:genetics / Q000276:immunology; D015678:Viral Structural Proteins / Q000235:genetics / Q000276:immunology*; D014765:Viral Vaccines / Q000008:administration & dosage / Q000235:genetics / Q000276:immunology*
chemical_list: D057134:Antibodies, Neutralizing; D000914:Antibodies, Viral; D004337:Drug Carriers; D011994:Recombinant Proteins; C082513:VP2 protein, infectious bursal disease virus; D014614:Vaccines, Synthetic; D015678:Viral Structural Proteins; D014765:Viral Vaccines
keywords: IBDV; VP2 protein; canarypox virus; viral vector