title: Dosimetric variability of the rats' exposure to electromagnetic pulses.
abstract: Rats' exposure to electromagnetic pulses (EMPs) has been conducted using an EMP simulator for various biological endpoints. In contrast, information about the EMP energy distribution and its variability in rats is lacking. EMPs are signals with spectrum concentrating in several hundred MHz, leading to EM absorption patterns different from those obtained at high frequencies. In this study, two anatomical models of rats (a male and a female) were reconstructed from magnetic resonance imaging. The models had the same posture as in the exposure experiments. Realistic EMPs were acquired directly from the EMP simulator and applied to the simulations. The interaction of the EMP with the rat was analyzed through the finite-difference time-domain method. Two approaches were utilized to calculate the energy absorption at the tissue and whole-body levels. Dosimetric variability due to incident directions, polarizations, exposure signals simplification, and rat separation was evaluated in this study. The variability result differed substantially from that of the non-constrained rats' exposure experiments. The result sensitivity to frequency and amplitude was discussed as well. The work can be used as a basis to determine the uncertainty and to formulate a standard experimental protocol for this type of experiment.
authors.affiliation: a College of Computer Science and Technology, Beijing University of Science and Technology , Beijing , China .|b China Academy of Telecommunication Research of Ministry of Industry and Information Technology , Beijing , China , and.
authors.forename: Congsheng
authors.initials: C
authors.lastname: Li
authors.affiliation: b China Academy of Telecommunication Research of Ministry of Industry and Information Technology , Beijing , China , and.
authors.forename: Lei
authors.initials: L
authors.lastname: Yang
authors.affiliation: c Schmid & Partner Eng. AG (SPEAG) , Zürich , Switzerland.
authors.forename: Chung-huan
authors.initials: CH
authors.lastname: Li
authors.affiliation: b China Academy of Telecommunication Research of Ministry of Industry and Information Technology , Beijing , China , and.
authors.forename: Yi
authors.initials: Y
authors.lastname: Xie
authors.affiliation: b China Academy of Telecommunication Research of Ministry of Industry and Information Technology , Beijing , China , and.
authors.forename: Tongning
authors.initials: T
authors.lastname: Wu
mesh_terms: D000818:Animals; D003952:Diagnostic Imaging; D060733:Electromagnetic Radiation; D005260:Female; D008279:Magnetic Resonance Imaging; D008297:Male; D008953:Models, Anatomic; D015233:Models, Statistical; D011874:Radiometry / Q000379:methods*; D051381:Rats; D012815:Signal Processing, Computer-Assisted; D012984:Software; D013997:Time Factors; D014916:Whole-Body Irradiation
keywords: Dosimetric variability; EMP exposure; Parseval's theorem; finite-difference time-domain