title: Advanced, neglected basal cell carcinoma.
abstract: Although basal cell carcinoma (BCC) rarely metastasizes and has a cure rate >95% when diagnosed early in its course, BCC causes significant morbidity and presents an enormous burden to the healthcare system worldwide. Patients who present late in the course of their disease are particularly challenging in that their treatment can be more complicated and less likely to be effective than had they presented earlier. Given the high prevalence of this malignancy and the morbidity associated with a late presentation, healthcare professionals should be familiar with the consequences of neglected BCCs, as well as their management after presentation. Knowledge of patient risk characteristics may allow earlier engagement and diagnosis of patients, before more significant morbidity occurs.
authors.affiliation: From the Yale University School of Medicine and the VA Connecticut Healthcare System, New Haven, Connecticut, and the Massachusetts Eye and Ear Infirmary, Boston.
authors.forename: Lauren E
authors.initials: LE
authors.lastname: Wiznia
authors.affiliation: From the Yale University School of Medicine and the VA Connecticut Healthcare System, New Haven, Connecticut, and the Massachusetts Eye and Ear Infirmary, Boston.
authors.forename: Kerry M
authors.initials: KM
authors.lastname: Shanley
authors.affiliation: From the Yale University School of Medicine and the VA Connecticut Healthcare System, New Haven, Connecticut, and the Massachusetts Eye and Ear Infirmary, Boston.
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Federman
mesh_terms: D002280:Basal Cell Carcinoma / Q000175:diagnosis* / Q000628:therapy; D057210:Delayed Diagnosis / Q000009:adverse effects*; D006801:Humans; D012307:Risk Factors; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000628:therapy