title: Suppressive Effect of High Hydrogen Generating High Amylose Cornstarch on Subacute Hepatic Ischemia-reperfusion Injury in Rats.
abstract: We examined whether feeding high hydrogen generating resistant starch could suppress subacute hepatic ischemia-reperfusion injury. Rats were fed a control diet with or without 20% high amylose cornstarch (HAS) supplementation for 14 days. On day 12, rats were subject to ischemia-reperfusion treatment. Portal hydrogen concentration was higher in the HAS group compared with the control group. Increased plasma alanine and aspartate aminotransferase activities due to ischemia-reperfusion treatment tended to decrease, and a significant reduction was observed by HAS feeding when compared with the control group. In conclusion, HAS, which enhances hydrogen generation in the hindgut, alleviated subacute hepatic ischemia-reperfusion injury.
authors.affiliation: Nayoro City University, Kita 8-1, Nishi 4, Nayoro, Hokkaido 096-8641, Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Tanabe
authors.affiliation: Nayoro City University, Kita 8-1, Nishi 4, Nayoro, Hokkaido 096-8641, Japan.
authors.forename: Yumi
authors.initials: Y
authors.lastname: Sasaki
authors.affiliation: Nayoro City University, Kita 8-1, Nishi 4, Nayoro, Hokkaido 096-8641, Japan.
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Yamamoto
authors.affiliation: Luminacoid Laboratory, Mure 4-1-4, Mitaka, Tokyo 181-0002, Japan.
authors.forename: Shuhachi
authors.initials: S
authors.lastname: Kiriyama
authors.affiliation: Nayoro City University, Kita 8-1, Nishi 4, Nayoro, Hokkaido 096-8641, Japan.
authors.forename: Naomichi
authors.initials: N
authors.lastname: Nishimura
keywords: antioxidant; high amylose cornstarch; hydrogen; ischemia-reperfusion; large intestine