title: Cervical arthroplasty for moderate to severe disc degeneration: clinical and radiological assessments after a minimum follow-up of 18 months--Pfirrmann grade and cervical arthroplasty.
abstract: OBJECTIVE
  Clinical outcomes and radiologic results after cervical arthroplasty have been reported in many articles, yet relatively few studies after cervical arthroplasty have been conducted in severe degenerative cervical disc disease.
  
  
  METHODS
  Sixty patients who underwent cervical arthroplasty (Mobi-C®) between April 2006 and November 2011 with a minimum follow-up of 18 months were enrolled in this study. Patients were divided into two groups according to Pfirrmann classification on preoperative cervical MR images: group A (Pfirrmann disc grade III, n=38) and group B (Pfirrmann disc grades IV or V, n=22). Visual analogue scale (VAS) scores of neck and arm pain, modified Oswestry Disability Index (mODI) score, and radiological results including cervical range of motion (ROM) were assessed before and after surgery.
  
  
  RESULTS
  VAS and mean mODI scores decreased after surgery from 5.1 and 57.6 to 2.7 and 31.5 in group A and from 6.1 and 59.9 to 3.7 and 38.4 in group B, respectively. In both groups, VAS and mODI scores significantly improved postoperatively (p<0.001), although no significant intergroup differences were found. Also, cervical dynamic ROM was preserved or gradually improved up to 18 months after cervical arthroplasty in both groups. Global, segmental and adjacent ROM was similar for both groups during follow-up. No cases of device subsidence or extrusion were recorded.
  
  
  CONCLUSIONS
  Clinical and radiological results following cervical arthroplasty in patients with severe degenerative cervical disc disease were no different from those in patients with mild degenerative cervical disc disease after 18 months of follow-up.
authors: Department of Neurosurgery, Guro Teun Teun Hospital, Seoul, Korea.
authors: Chang Hyun
authors: CH
authors: Oh
authors: Department of Neurosurgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
authors: Do Yeon
authors: DY
authors: Kim
authors: Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea.
authors: Gyu Yeul
authors: GY
authors: Ji
authors: Department of Radiology, Inha University Hospital, Incheon, Korea.
authors: Yeo Ju
authors: YJ
authors: Kim
authors: Department of Neurosurgery, Inha University Hospital, Incheon, Korea. nsyoon@gmail.com.
authors: Seung Hwan
authors: SH
authors: Yoon
authors: Department of Neurosurgery, Inha University Hospital, Incheon, Korea.
authors: Dongkeun
authors: D
authors: Hyun
authors: Department of Neurosurgery, Inha University Hospital, Incheon, Korea.
authors: Eun Young
authors: EY
authors: Kim
authors: Department of Neurosurgery, Inha University Hospital, Incheon, Korea.
authors: Hyeonseon
authors: H
authors: Park
authors: Department of Neurosurgery, Inha University Hospital, Incheon, Korea.
authors: Hyeong-Chun
authors: HC
authors: Park
mesh_terms: D000328:Adult; D001178:Arthroplasty / Q000379:methods*; D002574:Cervical Vertebrae / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007403:Intervertebral Disc / Q000601:surgery; D055959:Intervertebral Disc Degeneration / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016059:Range of Motion, Articular / Q000502:physiology; D012189:Retrospective Studies; D013122:Spinal Diseases / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult
keywords: Total disc replacement; cervical arthroplasty; clinical outcome; disc degeneration; range of motion