title: [Chemical constituents of Poria cocos].
abstract: The chemical constituents of Poria cocos were studied by means of silica gel, ODS column chromatography, Sephadex LH-20 and preparative HPLC. Thirteen compounds were isolated from this plant. By analysis of the ESI-MS and NMR data, the structures of these compounds were determined as tumulosic acid (1), dehydrotumulosic acid (2), 3beta, 5alpha-dihydroxy-ergosta-7, 22-dien-6-one (3), 3beta, 5alpha, 9alpha-trihydroxy-ergosta-7, 22-diene -6-one (4), ergosta-7, 22-diene-3-one (5), 6, 9-epoxy-ergosta-7,22-diene-3-ol (6), ergosta-4,22-diene-3-one (7), 3beta, 5alpha, 6beta-trihydroxyl-ergosta-7,22-diene (8), ergosta-5, 6-epoxy-7,22-dien-3-ol (9), beta-sitosterol (10), ribitol (11), mannitol (12), and oleanic acid 3-O-acetate (13), respectively. Compounds 3-13 were isolated from the P. cocos for the first time.
authors: Peng-Fei
authors: PF
authors: Yang
authors: Chao
authors: C
authors: Liu
authors: Hong-Qing
authors: HQ
authors: Wang
authors: Jia-Chun
authors: JC
authors: Li
authors: Zhen-Zhong
authors: ZZ
authors: Wang
authors: Wei
authors: W
authors: Xiao
authors: Ruo-Yun
authors: RY
authors: Chen
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry; D009930:Organic Chemicals / Q000032:analysis*; D055441:Poria / Q000737:chemistry*
chemical_list: D004365:Drugs, Chinese Herbal; D009930:Organic Chemicals