title: Glycomics - a new target for pharmaceuticals.
abstract: Most proteins show characteristic biological roles after modification with carbohydrates, and profiling of total carbohydrates (glycans) has been a big target for a full understanding of protein functions. Owing to extreme heterogeneity of the glycans, high sensitivity and high resolving power are required for their analysis. Combination of techniques using high-performance liquid chromatography, capillary electrophoresis and mass spectrometry allows comprehensive analysis of glycans derived from biological sources.:
authors: Department of Biochemistry, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan.
authors: Miyako
authors: M
authors: Nakano
authors: Department of Glycotherapeutics, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan.
authors: Akihiro
authors: A
authors: Kondo
authors: Faculty of Pharmaceutical Sciences, Kinki University, Kowakae 3-4-1, Higashi-osaka 577-8502, Japan. Electronic address:k_kakehi@phar.kindai.ac.jp.
authors: Kazuaki
authors: K
authors: Kakehi
authors: Department of Biochemistry, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan.
authors: Naoyuki
authors: N
authors: Taniguchi