title: Topography-guided photorefractive keratectomy for irregular astigmatism after small incision lenticule extraction.
abstract: OBJECTIVE
  To report the outcome of topography-guided photorefractive keratectomy (PRK) after complicated small incision lenticule extraction (SMILE).
  
  
  METHODS
  Retrospective case series of 5 eyes with irregular topography and ghost images after complicated SMILE. All eyes received transepithelial topography-guided PRK. Two eyes were treated with 0.02% mitomycin C. Patients were examined after a minimum of 3 months with evaluation of uncorrected (UDVA) and corrected (CDVA) distance visual acuity, Pentacam tomography (Oculus Optikgeräte, Wetzlar, Germany), and whole-eye aberrometry.
  
  
  RESULTS
  In 3 eyes, subjective symptoms were diminished and UDVA, CDVA, topography, and corneal wavefront aberrations were improved. The remaining 2 eyes developed significant haze with worsened topography and wavefront aberrations. One eye experienced a two-line reduction in CDVA. Eyes with haze development had not been treated with mitomycin C.
  
  
  CONCLUSIONS
  Transepithelial topography-guided PRK may reduce visual symptoms after complicated SMILE if postoperative haze can be controlled. To reduce the risk of haze development, application of mitomycin C may be considered.
authors: Anders
authors: A
authors: Ivarsen
authors: Jesper Ø
authors: JØ
authors: Hjortdal
mesh_terms: D001251:Astigmatism / Q000601:surgery*; D003319:Corneal Stroma / Q000601:surgery*; D019781:Corneal Topography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008866:Microsurgery / Q000379:methods; D018903:Photorefractive Keratectomy / Q000379:methods*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology