title: Reproducibility of qualitative assessments of temporal lobe atrophy in MRI studies.
abstract: OBJECTIVE
  To determine the reproducibility of the Scheltens visual rating scale in establishing atrophy of the medial temporal lobe.
  
  
  METHODS
  We used coronal T1-weighted inversion recovery sequences on a 1.5 Tesla MRI scanner to study 25 patients with clinically diagnosed Alzheimer's disease or mild cognitive decline and 25 subjects without cognitive decline. Five neuroradiologists trained to apply the Scheltens visual rating scale analyzed the images. We used the interclass correlation coefficient to evaluate interrater and intrarater agreement.
  
  
  RESULTS
  Raters scored 20 (80%) of the 25 patients with mild cognitive decline or Alzheimer's disease between 2 and 4; by contrast, they scored 21 (84%) of the 25 subjects without cognitive decline between 0 and 1. The interrater agreement was consistently greater than 0.82, with a 95% confidence interval of (0.7-0.9). The intrarater agreement ranged from 0.82 to 0.87, with a 95% confidence interval of (0.56-0.93).
  
  
  CONCLUSIONS
  The Scheltens visual rating scale is reproducible among observers, and this finding supports its use in clinical practice.
authors: Unitat Ressonància Magnètica (I.D.I.), Servei de Radiología, Hospital Universitari Vall d'Hebron, Barcelona, España. Electronic address: ssarria@idi-cat.org.
authors: S
authors: S
authors: Sarria-Estrada
authors: Unitat Ressonància Magnètica (I.D.I.), Servei de Radiología, Hospital Universitari Vall d'Hebron, Barcelona, España.
authors: C
authors: C
authors: Acevedo
authors: Unitat Ressonància Magnètica (I.D.I.), Servei de Radiología, Hospital Universitari Vall d'Hebron, Barcelona, España.
authors: R
authors: R
authors: Mitjana
authors: Unitat Ressonància Magnètica (I.D.I.), Servei de Radiología, Hospital Universitari Vall d'Hebron, Barcelona, España.
authors: L
authors: L
authors: Frascheri
authors: Unitat Ressonància Magnètica (I.D.I.), Servei de Radiología, Hospital Universitari Vall d'Hebron, Barcelona, España.
authors: S
authors: S
authors: Siurana
authors: Unitat Ressonància Magnètica (I.D.I.), Servei de Radiología, Hospital Universitari Vall d'Hebron, Barcelona, España.
authors: C
authors: C
authors: Auger
authors: Unitat Ressonància Magnètica (I.D.I.), Servei de Radiología, Hospital Universitari Vall d'Hebron, Barcelona, España.
authors: A
authors: A
authors: Rovira
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000000981:diagnostic imaging; D001284:Atrophy; D003072:Cognition Disorders / Q000000981:diagnostic imaging; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D015203:Reproducibility of Results; D013702:Temporal Lobe / Q000000981:diagnostic imaging* / Q000473:pathology*
keywords: Alzheimer's disease; Atrofia cerebral; Brain atrophy; Demencia; Dementia; Deterioro cognitivo leve; Enfermedad de Alzheimer; Lóbulo temporal; Mild cognitive decline; Temporal lobe