title: A new sesquiterpene lactone from the fruits of Illicium henryi.
abstract: OBJECTIVE
  To study the chemical constituents of the fruits of Illicium henryi.
  
  
  METHODS
  Chromatographic separations on silica gel, Sephadex LH-20 gel and MCI gel were used to isolate the compounds. The structures were elucidated based on extensive spectroscopic data analyses.
  
  
  RESULTS
  Seven compounds were obtained and their structures were identified as 10-benzoyl-cycloparvifloralone (1), cycloparvifloralone (2), 2α-hydroxycycloparviforalone (3), henrylactone B (4), merrillianone (5), henrylactone C (6) and 7, 14-ortholactone- 3-hydroxyfloridanolide (7).
  
  
  CONCLUSIONS
  Compound 1 is a new sesquiterpene lactone. The tested compounds showed weak anti-HBV activities on HBV surface antigen (HBsAg) secretion and HBV e antigen (HBeAg) secretion using Hep G2.2.15 cell line.
authors: School of Pharmaceutical Science, Zhengzhou University, Zhengzhou 450001, China. Electronic address: liujf2009y@126.com.
authors: Ji-Feng
authors: JF
authors: Liu
authors: School of Pharmaceutical Science, Zhengzhou University, Zhengzhou 450001, China.
authors: Hui-Juan
authors: HJ
authors: Li
authors: School of Pharmaceutical Science, Zhengzhou University, Zhengzhou 450001, China; Henan Key laboratory for Pharmacology of Liver Disease, Academy of Medical and Pharmaceutical Science, Zhengzhou University, Zhengzhou 450052, China.
authors: Jing-Min
authors: JM
authors: Zhang
authors: School of Pharmaceutical Science, Zhengzhou University, Zhengzhou 450001, China.
authors: Li-Xia
authors: LX
authors: Wang
authors: School of Pharmaceutical Science, Zhengzhou University, Zhengzhou 450001, China; Henan Key laboratory for Pharmacology of Liver Disease, Academy of Medical and Pharmaceutical Science, Zhengzhou University, Zhengzhou 450052, China.
authors: Ya-Feng
authors: YF
authors: Wang
authors: School of Pharmaceutical Science, Henan University of Traditional Chinese Medicine, Zhengzhou 450008, China.
authors: Meng-Qi
authors: MQ
authors: Liu
authors: School of Pharmaceutical Science, Zhengzhou University, Zhengzhou 450001, China.
authors: Yue-Feng
authors: YF
authors: Bi
authors: School of Pharmaceutical Science, Zhengzhou University, Zhengzhou 450001, China.
authors: Yan-Bing
authors: YB
authors: Zhang
mesh_terms: D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005638:Fruit / Q000737:chemistry*; D056945:Hep G2 Cells; D006515:Hepatitis B virus / Q000187:drug effects; D006801:Humans; D029523:Illicium / Q000737:chemistry*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: C000594945:10-benzoyl-cycloparvifloralone; D000998:Antiviral Agents; D010936:Plant Extracts; D012717:Sesquiterpenes
keywords: Anti-HBV activity; Illicium henryi; Sesquiterpene lactones