title: [Systematic review of antimicrobial resistance in Enterobacteriaceae isolates from Colombian hospitals].
abstract: BACKGROUND
  Bacterial resistance is a public health problem worldwide that seriously compromises the possibility to treat infections.
  
  
  OBJECTIVE
  To identify levels of resistance to antibiotic markers in Enterobacteriaceae isolates from Colombian hospitals.
  
  
  METHODS
  A systematic literature survey was done including articles indexed in Medline, Embase and LILACS. A manual search was made of Colombian scientific journals and other publications on infectious disease that were not available electronically.
  
  
  RESULTS
  In total, 43 observational studies and epidemiological reports were identified with information about resistance among Enterobacteriaceae isolates in Colombian hospitals, mainly from Bogotá, Cali and Medellín. The resistance rate of Escherichia coli ranges from 3 to 11%, 5 to 20% and from 0.2 to 0.8% for piperacillin-tazobactam, third generation cephalosporins and carbapenems, respectively. For Klebsiella pneumoniae resistance rates ranges from 21.8 to 48.1% to piperacillin-tazobactam, 20 to 35% to broad-spectrum cephalosporins and 3 to 8% to carbapenems, with significant variations by cities, levels of care and clinical settings.
  
  
  CONCLUSIONS
  The spread of bacterial resistance in Enterobacteriaceae isolated in Colombian hospitals is a growing problem that calls for priority action to cut the chains of transmission.
authors: Departamento de Medicina Interna, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, D.C, Colombia.
authors: Leidy
authors: L
authors: González
authors: Grupo de Investigación en Enfermedades Infecciosas, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, D.C, Colombia.
authors: Jorge Alberto
authors: JA
authors: Cortés
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D003105:Colombia / Q000453:epidemiology; D003428:Cross Infection / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D024901:Drug Resistance, Multiple, Bacterial; D004755:Enterobacteriaceae / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D006748:Hospital Departments / Q000706:statistics & numerical data; D006801:Humans; D007362:Intensive Care Units / Q000706:statistics & numerical data; D015337:Multicenter Studies as Topic; D064887:Observational Studies as Topic; D011159:Population Surveillance
chemical_list: D000900:Anti-Bacterial Agents