title: Anxiety, sedation, and simulated driving in binge drinkers.
abstract: The current study evaluated the relationships among trait anxiety, subjective response to alcohol, and simulated driving following a simulated alcohol binge. Sixty drinkers with a binge history completed the State Trait Anxiety Inventory (STAI), the Alcohol Use Questionnaire, and subsequently completed a driving simulation. Participants were then administered 0.2 g/kg ethanol at 30-min intervals (cumulative dose 0.8 g/kg). Following alcohol consumption, the Biphasic Alcohol Effects Scale (BAES) and visual analog scales of subjective impairment and driving confidence were administered, after which simulated driving was reassessed. Due to the emphasis on simulated driving after drinking in the current study, subjective response to alcohol (i.e., self-reported sedation, stimulation, impairment, and confidence in driving ability) was assessed once following alcohol consumption, as this is the time when drinkers tend to make decisions regarding legal driving ability. Alcohol increased driving speed, speeding tickets, and collisions. Sedation following alcohol predicted increased subjective impairment and decreased driving confidence. Subjective impairment was not predicted by sensitivity to stimulation or trait anxiety. High trait anxiety predicted low driving confidence after drinking and this relationship was mediated by sedation. Increased speed after alcohol was predicted by sedation, but not by trait anxiety or stimulation. Anxiety, combined with the sedating effects of alcohol, may indicate when consumption should cease. However, once driving is initiated, sensitivity to sedation following alcohol consumption is positively related to simulated driving speed.
authors: Neuroscience Program, Wake Forest School of Medicine.
authors: Elizabeth R
authors: ER
authors: Aston
authors: Department of Physiology and Pharmacology, Wake Forest School of Medicine.
authors: Erin E
authors: EE
authors: Shannon
authors: Neuroscience Program, Wake Forest School of Medicine.
authors: Anthony
authors: A
authors: Liguori
mesh_terms: D000328:Adult; D000428:Alcohol Drinking; D000435:Alcoholic Intoxication / Q000503:physiopathology*; D000437:Alcoholism; D001007:Anxiety; D001334:Automobile Driving; D063425:Binge Drinking / Q000503:physiopathology*; D002492:Central Nervous System Depressants / Q000494:pharmacology*; D003198:Computer Simulation; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives; D008297:Male; D008875:Middle Aged; D012649:Self Concept; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D002492:Central Nervous System Depressants; D006993:Hypnotics and Sedatives; D000431:Ethanol