title: Simultaneous determination of bisphenols and alkylphenols in water by solid phase extraction and ultra performance liquid chromatography-tandem mass spectrometry.
abstract: To establish an analytical method for determination of four bisphenols (BPA, BPB, BPF, and BPS) and two alkylphenols (4-n-OP, 4-n-NP) in water by ultra performance liquid chromatography- tandem mass spectrometry (UPLC/MS/MS). The water samples were extracted and condensed with solid-phase extraction (SPE) using C18 cartridges and eluted by acetonitrile. Separation was carried out with Acquity BEH C8 column and detection were performed by UPLC/MS/MS. Quantification was calculated by using the internal standard BPA-d16 and 4-n-NP-d8. The linear correlation coefficients of these compounds in the range of 1.0-100.0 μg/L were all over 0.999. The minimum detectable concentrations were 0.75-1.0 ng/L, and the recoveries ranged from 87.0% to 106.9%. Relative standard deviations (RSDs) were between 1.26% and 3.67%. Applying this method to detect the source water of Chaohu Lake and drinking water of Hefei, six target compounds were detected in different levels. This method is simple with high sensitivity and selectivity, could be suitable for the determination of these compounds in source and drinking water.
authors: Anhui Provincial Center for Disease Control and Prevention, Hefei 230601, Anhui, China; School of Public Health, Anhui Medical University, Hefei 230032, Anhui, China.
authors: Xiao Mei
authors: XM
authors: Shan
authors: School of Public Health, Anhui Medical University, Hefei 230032, Anhui, China.
authors: Deng Hui
authors: DH
authors: Shen
authors: School of Public Health, Anhui Medical University, Hefei 230032, Anhui, China.
authors: Bing Shuang
authors: BS
authors: Wang
authors: Ningbo City Center for Disease Control and Prevention, Ningbo 315010, Zhejiang, China.
authors: Bei Bei
authors: BB
authors: Lu
authors: Anhui Provincial Center for Disease Control and Prevention, Hefei 230601, Anhui, China.
authors: Fa Yuan
authors: FY
authors: Huang
mesh_terms: D002853:Chromatography, Liquid; D052244:Endocrine Disruptors / Q000032:analysis*; D010636:Phenols / Q000032:analysis*; D052616:Solid Phase Extraction; D053719:Tandem Mass Spectrometry; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D052244:Endocrine Disruptors; D010636:Phenols; D014874:Water Pollutants, Chemical