title: Radiogenomics: radiobiology enters the era of big data and team science.
authors: Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, New York; Departments of Genetics and Genomic Sciences, Dermatology, and Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York, New York; Department of Radiation Oncology, New York University School of Medicine, New York, New York. Electronic address: barry.rosenstein@mssm.edu.
authors: Barry S
authors: BS
authors: Rosenstein
authors: Translational Radiobiology Group, Institute of Cancer Sciences, The University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, Manchester, UK.
authors: Catharine M
authors: CM
authors: West
authors: Division of Biostatistics and Bioinformatics, University of Maryland Greenebaum Cancer Center, and Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.
authors: Søren M
authors: SM
authors: Bentzen
authors: Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark.
authors: Jan
authors: J
authors: Alsner
authors: Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark.
authors: Christian Nicolaj
authors: CN
authors: Andreassen
authors: Department of Radiation Oncology, Institute of Cancer of Montpellier (INSERM), Center for Cancer Research, Montpellier, France.
authors: David
authors: D
authors: Azria
authors: Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.
authors: Gillian C
authors: GC
authors: Barnett
authors: Department of Radiation Oncology and OncoRay National Center for Radiation Research in Oncology, Technische Universität Dresden, and Helmholtz-Zentrum Dresden-Rossendorf Dresden, Germany.
authors: Michael
authors: M
authors: Baumann
authors: University of Cambridge Department of Oncology, Cambridge Biomedical Campus, Addenbrooke's Hospital, Cambridge, UK.
authors: Neil
authors: N
authors: Burnet
authors: Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
authors: Jenny
authors: J
authors: Chang-Claude
authors: Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan.
authors: Eric Y
authors: EY
authors: Chuang
authors: Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
authors: Charlotte E
authors: CE
authors: Coles
authors: Department of Radiation Oncology (MAASTRO), GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
authors: Andre
authors: A
authors: Dekker
authors: Department of Basic Medical Sciences, Ghent University, Ghent, Belgium.
authors: Kim
authors: K
authors: De Ruyck
authors: Radiation Oncology, University Hospitals Leuven, and Department of Oncology, KU Leuven, Belgium.
authors: Dirk
authors: D
authors: De Ruysscher
authors: Department of Oncology, Rambam Health Care Campus, Haifa, Israel.
authors: Karen
authors: K
authors: Drumea
authors: Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.
authors: Alison M
authors: AM
authors: Dunning
authors: Department of Public Health and Primary Care and Department of Oncology, University of Cambridge, Cambridge, UK.
authors: Douglas
authors: D
authors: Easton
authors: Division of Cancer Genetics and Epidemiology, The Institute of Cancer Research, Sutton, UK.
authors: Rosalind
authors: R
authors: Eeles
authors: Fundación Pública Galega de Medicina Xenómica-SERGAS, Grupo de Medicina Xenómica-USC, CIBERER, IDIS, Santiago de Compostela, Spain.
authors: Laura
authors: L
authors: Fachal
authors: Oncogenetics Group, Vall d'Hebron Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, Barcelona, Spain.
authors: Sara
authors: S
authors: Gutiérrez-Enríquez
authors: Radiation Oncology, University Hospitals Leuven, and Department of Oncology, KU Leuven, Belgium.
authors: Karin
authors: K
authors: Haustermans
authors: Department of Radiation Oncology, Hospital Universitario de Gran Canaria Dr. Negrin, Las Palmas de Gran Canaria, Spain.
authors: Luis Alberto
authors: LA
authors: Henríquez-Hernández
authors: Advanced Radiation Biology Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan.
authors: Takashi
authors: T
authors: Imai
authors: Department Cancer Studies and Molecular Medicine, University of Leicester, Leicester, UK.
authors: George D D
authors: GD
authors: Jones
authors: Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, New York.
authors: Sarah L
authors: SL
authors: Kerns
authors: Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
authors: Zhongxing
authors: Z
authors: Liao
authors: Department of Pediatrics, The University of Chicago, Chicago, Illinois.
authors: Kenan
authors: K
authors: Onel
authors: Departments of Pathology, Genetics and Pediatrics, Albert Einstein College of Medicine at Yeshiva University, New York, New York.
authors: Harry
authors: H
authors: Ostrer
authors: Department of Radiation Oncology, Cross Cancer Institute, University of Alberta, Edmonton, Alberta, Canada.
authors: Matthew
authors: M
authors: Parliament
authors: Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
authors: Paul D P
authors: PD
authors: Pharoah
authors: Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, and Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
authors: Timothy R
authors: TR
authors: Rebbeck
authors: Department of Genetics, University of Leicester, Leicester, UK.
authors: Christopher J
authors: CJ
authors: Talbot
authors: Department of Basic Medical Sciences, Ghent University, Ghent, Belgium.
authors: Hubert
authors: H
authors: Thierens
authors: Fundación Pública Galega de Medicina Xenómica-SERGAS, Grupo de Medicina Xenómica-USC, CIBERER, IDIS, Santiago de Compostela, Spain.
authors: Ana
authors: A
authors: Vega
authors: Department of Epidemiology and Biostatistics, Institute for Human Genetics, University of California, San Francisco, California.
authors: John S
authors: JS
authors: Witte
authors: Department of Radiation Oncology, Centre Hospitalier de l'Université de Montréal, Montréal, Quebec, Canada.
authors: Philip
authors: P
authors: Wong
authors: Department of Basic Medical Sciences, Center for Applied Nanobioscience and Medicine, College of Medicine Phoenix, University of Arizona, Phoenix, Arizona.
authors: Frederic
authors: F
authors: Zenhausern
mesh_terms: D000483:Alleles; D002869:Chromosome Aberrations; D020022:Genetic Predisposition to Disease / Q000235:genetics; D055106:Genome-Wide Association Study / Q000379:methods*; D023281:Genomics / Q000379:methods*; D005838:Genotype; D006801:Humans; D009369:Neoplasms / Q000235:genetics / Q000532:radiotherapy*; D010641:Phenotype; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D011832:Radiation Injuries / Q000235:genetics*; D011836:Radiation Tolerance / Q000235:genetics; D011879:Radiotherapy Dosage; D018401:Sample Size