title: Langerhans cell histiocytosis presenting as isolated mediastinal mass in an infant.
abstract: BACKGROUND
  Isolated mediastinal involvement in Langerhans cell histiocytosis (LCH) has been rarely reported.
  
  
  METHODS
  A 3-month-old boy presented with history of low grade intermittent fever, cough and noisy breathing for 2 weeks.
  
  
  METHODS
  A chest X-ray showed massive mediastinal widening. Biopsy of the mass confirmed LCH.
  
  
  RESULTS
  Patient is doing well after one year of treatment with LCH III protocol.
  
  
  CONCLUSIONS
  Langerhans cell histiocytosis should be considered in differential diagnosis of mediastinal mass in infants.
authors: Pediatric Hematology Oncology and BMT Unit, Department of Pediatrics, Fortis Memorial Research Institute, Gurgaon, Haryana, India. Correspondence to: Dr Satya P Yadav, Department of Pediatrics, Fortis Memorial Research Institute, Gurgaon, Haryana, India. satya_1026@hotmail.com.
authors: Mohammed
authors: M
authors: Ramzan
authors: Satya Prakash
authors: SP
authors: Yadav
mesh_terms: D003937:Diagnosis, Differential; D006646:Histiocytosis, Langerhans-Cell; D006801:Humans; D007223:Infant; D008297:Male; D008477:Mediastinal Diseases