title: Five polyostotic conditions that general orthopedic surgeons should recognize (or should not miss).
abstract: General orthopedic surgeons frequently encounter patients with conditions affecting multiple bones. It is important to recognize common polyostotic diseases. This article describes five polyostotic conditions: Multipe Enchondromatosis (Ollier Disease and Maffucci syndrome), Multiple Hereditary Exostosis (Diaphyseal Aclasis), Fibrous Dysplasia (McCune-Albright syndrome and Mazabraud syndrome), Paget's Disease of bone (Osteitis Deformans), and Skeletal Metastases. This is a survey of the clinical, pathologic and radiographic features that assist in diagnosing these conditions. Also, an overview of the laboratory findings, treatment, follow-up, and prognosis is presented. Recognizing these diseases will aid in prompt and accurate diagnosis and appropriate referral and therapy.
authors: Department of Orthopaedic Surgery, University of Miami Miller School of Medicine, 1400 NW 12th Avenue, Suite 4036, Miami, FL 33136, USA.
authors: Saravanaraja
authors: S
authors: Muthusamy
authors: Department of Orthopaedic Surgery, University of Miami Miller School of Medicine, 1400 NW 12th Avenue, Suite 4036, Miami, FL 33136, USA.
authors: Sheila A
authors: SA
authors: Conway
authors: Department of Orthopaedic Surgery, University of Miami Miller School of Medicine, 1400 NW 12th Avenue, Suite 4036, Miami, FL 33136, USA. Electronic address: HTemple@med.miami.edu.
authors: H Thomas
authors: HT
authors: Temple
mesh_terms: D001859:Bone Neoplasms / Q000175:diagnosis* / Q000556:secondary / Q000601:surgery; D002114:Calcinosis / Q000000981:diagnostic imaging; D004687:Enchondromatosis / Q000175:diagnosis* / Q000601:surgery; D005097:Exostoses, Multiple Hereditary / Q000175:diagnosis* / Q000601:surgery; D005269:Femur / Q000000981:diagnostic imaging; D005357:Fibrous Dysplasia of Bone / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D010001:Osteitis Deformans / Q000175:diagnosis* / Q000601:surgery; D011379:Prognosis; D013977:Tibia / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed
keywords: Fibrous dysplasia; Maffucci syndrome; Multiple exostosis; Ollier disease; Paget disease; Polyostotic; Skeletal metastases