title: Increasing Thermal Stability of Gelatin by UV-Induced Cross-Linking with Glucose.
abstract: The effects of ultraviolet (254 nm) radiation on a hydrated gelatin-glucose matrix were investigated for the development of a physiologically thermostable substrate for potential use in cell scaffold production. Experiments conducted with a differential scanning calorimeter indicate that ultraviolet irradiation of gelatin-glucose hydrogels dramatically increases thermal stability such that no melting is observed at temperatures of at least 90°C. The addition of glucose significantly increases the yield of cross-linked product, suggesting that glucose has a role in cross-link formation. Comparisons of lyophilized samples using scanning electron microscopy show that irradiated materials have visibly different densities.
authors: Stanford University, Stanford, CA 94305, USA.
authors: Evan M
authors: EM
authors: Masutani
authors: Hawaii Natural Energy Institute, University of Hawaii, 1680 East West Road, POST 109, Honolulu, HI 96822, USA.
authors: Christopher K
authors: CK
authors: Kinoshita
authors: Hawaii Natural Energy Institute, University of Hawaii, 1680 East West Road, POST 109, Honolulu, HI 96822, USA.
authors: Travis T
authors: TT
authors: Tanaka
authors: University of Pennsylvania, Philadelphia, PA 19104, USA.
authors: Andrew K D
authors: AK
authors: Ellison
authors: Hawaii Natural Energy Institute, University of Hawaii, 1680 East West Road, POST 109, Honolulu, HI 96822, USA.
authors: Brandon A
authors: BA
authors: Yoza