title: Young male patient diagnosed with cutaneous polyarteritis nodosa successfully treated with etanercept.
abstract: Cutaneous polyarteritis nodosa (CPAN) is a form of necrotizing vasculitis of small and medium-sized arteries. It is limited to the skin and has a recurrent and chronic course, possibly associated with fever, arthralgia, myalgia and neuropathy, but without visceral involvement. We report the clinical case of a 7-year-old male patient with CPAN refractory to treatment with high doses of corticoids and cyclophosphamide, who was successfully treated with the TNF-α (tumor necrosis factor-alpha) inhibitor, etanercept, in monotherapy.
authors: Rheumatology Department, Gregorio Marañón University, General Hospital , Madrid , Spain.
authors: Lara
authors: L
authors: Valor
authors: Indalecio
authors: I
authors: Monteagudo
authors: Inmaculada
authors: I
authors: de la Torre
authors: Carlos González
authors: CG
authors: Fernández
authors: María
authors: M
authors: Montoro
authors: Javier López
authors: JL
authors: Longo
authors: Luis
authors: L
authors: Carreño
mesh_terms: D002648:Child; D000068800:Etanercept; D006801:Humans; D007074:Immunoglobulin G / Q000627:therapeutic use*; D007155:Immunologic Factors / Q000627:therapeutic use*; D008297:Male; D010488:Polyarteritis Nodosa / Q000188:drug therapy*; D018124:Receptors, Tumor Necrosis Factor / Q000627:therapeutic use*; D012871:Skin Diseases / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D007074:Immunoglobulin G; D007155:Immunologic Factors; D018124:Receptors, Tumor Necrosis Factor; D000068800:Etanercept
keywords: Anti-TNF-α; Cutaneous polyarteritis nodosa (CPAN); Etanercept; Polyarteritis nodosa; TNF-α