title: Outbreak of Vibrio cholerae serogroup O1, serotype Ogawa, biotype El Tor strain--La Huasteca Region, Mexico, 2013.
abstract: On September 2 and 6, 2013, Mexico's National System of Epidemiological Surveillance identified two cases of cholera in Mexico City. Rectal swab cultures from both patients were confirmed as toxigenic Vibrio cholerae serogroup O1, serotype Ogawa, biotype El Tor. Pulsed-field gel electrophoresis and virulence gene amplification (ctxA, ctxB, zot, and ace) demonstrated that the strains were identical to one another but different from strains circulating in Mexico previously. The strains were indistinguishable from the strain that has caused outbreaks in Haiti, the Dominican Republic, and Cuba. The strain was susceptible to doxycycline, had intermediate susceptibility to ampicillin and chloramphenicol, was less than fully susceptible to ciprofloxacin, and was resistant to furazolidone and trimethoprim-sulfamethoxazole. An investigation failed to identify a common source of infection, additional cases, or any epidemiologic link between the cases. Both patients were treated with a single, 300-mg dose of doxycycline, and their symptoms resolved.
authors: Alberto
authors: A
authors: Díaz-Quiñonez
authors: Irma
authors: I
authors: Hernández-Monroy
authors: Norma
authors: N
authors: Montes-Colima
authors: Asunción
authors: A
authors: Moreno-Pérez
authors: Adriana
authors: A
authors: Galicia-Nicolás
authors: Hugo
authors: H
authors: Martínez-Rojano
authors: Concepción
authors: C
authors: Carmona-Ramos
authors: Miroslava
authors: M
authors: Sánchez-Mendoza
authors: José Cruz
authors: JC
authors: Rodríguez-Martínez
authors: Lorena
authors: L
authors: Suárez-Idueta
authors: María Eugenia
authors: ME
authors: Jiménez-Corona
authors: Cuitláhuac
authors: C
authors: Ruiz-Matus
authors: Pablo
authors: P
authors: Kuri-Morales
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D002771:Cholera / Q000453:epidemiology* / Q000382:microbiology; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D012703:Serotyping; D041241:Vibrio cholerae O1 / Q000145:classification* / Q000302:isolation & purification; D055815:Young Adult