title: Diagnostic accuracy of the Phototest for cognitive impairment and dementia in Argentina.
abstract: Phototest is a simple, easy and very brief test with theoretical advantages over available dementia screening tests in Spain. The objective of this study was to estimate the diagnostic accuracy of the Phototest for cognitive impairment and dementia and to compare it with that of the MMSE and the Clock Drawing Test (CDT) in an Argentine population. A phase II cross-sectional study of diagnostic tests evaluation was performed in a sample of 30 controls, 61 with amnestic mild cognitive impairment (a-MCI), and 56 with mild Alzheimer type dementia (DAT). The diagnostic accuracy (DA) was assessed in relation to the clinical diagnosis by calculating the area under the ROC curve (UAC), Sensitivity (Sn), and Specificity (Sp).The DA of the Phototest for a-MCI and DAT (0.93 and 0.97 [UAC]) was higher than that of the MMSE and the CDT. The cut-off points of 27/28 for DAT (Sn = 89.29 [78.1-96.0], Sp = 96.67 [82.8-99.9]) and 30/31 for a-MCI (Sn = 85.25 [73.8-93.0], Sp = 90.00 [73.5-97.9]) maximized the sum of Sn and Sp. Phototest correlates significantly with MMSE and CDT. The Phototest is an efficient instrument for the detection of mild dementia or MCI, with good accuracy and good correlation with tests measuring overall cognitive impairment.
authors: a Department of Cognitive Neurology , Instituto de Investigaciones Neurológicas Raúl Carrea (FLENI) , Buenos Aires , Argentina.
authors: María Julieta
authors: MJ
authors: Russo
authors: Mónica
authors: M
authors: Iturry
authors: María Alejandra
authors: MA
authors: Sraka
authors: Leonardo
authors: L
authors: Bartoloni
authors: Cristóbal
authors: C
authors: Carnero Pardo
authors: Ricardo Francisco
authors: RF
authors: Allegri
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis*; D001118:Argentina; D010054:Brief Psychiatric Rating Scale / Q000592:standards*; D060825:Cognitive Dysfunction / Q000175:diagnosis*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000592:standards*; D012372:ROC Curve; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
keywords: Accuracy; Alzheimer’s disease; Mild cognitive impairment; Screening.