title: Outcomes in patients with heart failure with preserved ejection fraction.
abstract: Heart failure with preserved ejection fraction (HF-PEF) represents a heterogenous group of patients with HF, more commonly affecting older women, with a history of hypertension and, less commonly, coronary disease, than patients with HF with reduced ejection fraction (HF-REF). Patients with HF-PEF have lower short-term and longer-term mortality than patients with HF-REF. At present, therapeutic interventions that have had proven benefits for patients with HF with reduced EF have not been shown to have similar benefits for patients with HF-PEF and there remains an urgent need for new therapeutic strategies to improve the clinical outcomes for patients with HF-PEF.
authors: Department of Medicine, National Institute for Health Innovation, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
authors: Katrina K
authors: KK
authors: Poppe
authors: Department of Medicine, National Institute for Health Innovation, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand; Greenlane Cardiovascular Service, Auckland City Hospital, Private Bag 92024, Auckland 1142, New Zealand. Electronic address: r.doughty@auckland.ac.nz.
authors: Robert N
authors: RN
authors: Doughty
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D002303:Cardiac Output, Low / Q000175:diagnosis* / Q000401:mortality; D002423:Cause of Death; D005260:Female; D006333:Heart Failure / Q000175:diagnosis / Q000188:drug therapy* / Q000401:mortality*; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D010343:Patient Admission / Q000706:statistics & numerical data; D010359:Patient Readmission / Q000706:statistics & numerical data; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic; D012016:Reference Values; D012084:Renin-Angiotensin System / Q000187:drug effects; D018570:Risk Assessment; D012720:Severity of Illness Index; D013318:Stroke Volume / Q000502:physiology*; D015996:Survival Rate; D013577:Syndrome; D016896:Treatment Outcome
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors
keywords: Heart failure; Preserved ejection fraction; Reduced ejection fraction