title: Integrative bioinformatics: making sense of the networks.
abstract: The focus of biology has shifted from the investigation of individual genes and proteins to the study of large complex networks featuring interactions between tens of thousands of molecular and cellular components. Information on these networks is obtained from genome-scale experimental and theoretical analyses, which yield valuable but noisy data, on biological processes that are still poorly understood. The new exciting developments in bioinformatics show great promise in meeting the challenge of extracting biological insight from these data.:
authors: Biochemistry Department, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ont., Canada M5S 1A8. Electronic address:Shoshana@sickkids.ca.
authors: Shoshana J
authors: SJ
authors: Wodak
authors: School of Information Technology and Engineering, University of Ottawa, 800 King Edward Avenue, P.O. Box 450, Stn. A, Ottawa, Ont., Canada K1N 6N5. Electronic address:http://www.site.uottawa.ca.
authors: Jeffrey
authors: J
authors: Castura
authors: Department of Structural Biology and Biochemistry, Hospital for Sick Children, 555 University Avenue, Toronto, Ont., Canada M5G 1X8.
authors: Chris
authors: C
authors: Orsi