title: Chemotherapy-enhanced inflammation may lead to the failure of therapy and metastasis.
abstract: The lack of therapy and the failure of existing therapy has been a challenge for clinicians in treating various cancers. Doxorubicin, 5-fluorouracil, cisplatin, and paclitaxel are the first-line therapy in various cancers; however, toxicity, resistance, and treatment failure limit their clinical use. Their status leads us to discover and investigate more targeted therapy with more efficacy. In this article, we dissect literature from the patient perspective, the tumor biology perspective, therapy-induced metastasis, and cell data generated in the laboratory.
authors: College of Human Medicine, Michigan State University, East Lansing, MI, USA.
authors: Dinesh
authors: D
authors: Vyas
authors: College of Human Medicine, Michigan State University, East Lansing, MI, USA.
authors: Gieric
authors: G
authors: Laput
authors: College of Human Medicine, Michigan State University, East Lansing, MI, USA.
authors: Arpitak K
authors: AK
authors: Vyas
keywords: cancer; chemotherapy; inflammation