title: Zingiber officinale: A Potential Plant against Rheumatoid Arthritis.
abstract: Rheumatoid arthritis (RA) is an autoimmune disease particularly affecting elderly people which leads to massive bone destruction with consequent inflammation, pain, and debility. Allopathic medicine can provide only symptomatic relief. However, Zingiber officinale is a plant belonging to the Zingiberaceae family, which has traditionally been used for treatment of RA in alternative medicines of many countries. Many of the phytochemical constituents of the rhizomes of this plant have therapeutic benefits including amelioration of RA. This review attempts to list those phytochemical constituents with their reported mechanisms of action. It is concluded that these phytochemicals can form the basis of discovery of new drugs, which not only can provide symptomatic relief but also may provide total relief from RA by stopping RA-induced bone destruction. As the development of RA is a complex process, further research should be continued towards elucidating the molecular details leading to RA and drugs that can stop or reverse these processes by phytoconstituents of ginger.
authors: Department of Pharmacy, University of Development Alternative, Dhanmondi, Dhaka 1209, Bangladesh.
authors: Abdullah
authors: A
authors: Al-Nahain
authors: Department of Biotechnology and Genetic Engineering, University of Development Alternative, Dhaka 1209, Bangladesh.
authors: Rownak
authors: R
authors: Jahan
authors: Department of Pharmacy, University of Development Alternative, Dhanmondi, Dhaka 1209, Bangladesh.
authors: Mohammed
authors: 0000-0002-0216-7977
authors: M
authors: Rahmatullah