title: [Caries prevention effect of resin based sealants and glass ionomor sealants].
abstract: OBJECTIVE
  To evaluate the effectiveness of resin-based sealants and glass ionomer sealants on caries prevention in the first permanent molars.
  
  
  METHODS
  A randomized controlled, examiner-blinded, 2-year clinical trial with parallel groups was conducted. A total of 419 children (664 first molars) who had at least one sound first permanent molar with deep fissures or fissures with signs of non-cavitated lesions were recruited. They were randomly allocated into three groups.Helioseal F, a light-cured resin-based sealants was used in group R (136 children with 219 first molars). FUJI VII, a light-cured glass ionomer sealants was used in group G (130 children with 218 first molars) and group N (153 children with 227 first molars) was blank control.Follow-up examinations were conducted at 6, 12, and 24 month after sealing to examine the sealants retention and caries incidence. Chi-square test was used to compare the differences of caries incidence among the 3 groups.Generalized estimating equations (GEE) was used to analyze the effective factors of caries incidence.
  
  
  RESULTS
  During the 2-year follow-up period, 3.0% (6/197) of the teeth in group R, 6.7% (13/193) of the teeth in group G, and 14.7% (29/197) of the teeth in group N were diagnosed as having developed a cavitated lesion. The difference in the incidence of caries among the three groups was significant(P < 0.05). No significant difference in caries incidence was found between group R and group G (P > 0.05). The tooth-level preventive fractions were 79.6% for resin-based sealants and 54.4% for glass ionomer sealants, respectively.
  
  
  CONCLUSIONS
  Both resin-based sealants and glass ionomer sealants can effectively prevent the incidence of caries in the first permanent molars. The two sealants have similar caries prevention effect.
authors: Department of Preventive Dentistry, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors: Yijie
authors: Y
authors: Liu
authors: Email: rongwensheng@vip.sina.com.
authors: Wensheng
authors: W
authors: Rong
authors: Xiulan
authors: X
authors: Zhao
authors: Meng
authors: M
authors: Wang
authors: Quanchun
authors: Q
authors: Jiang
authors: Weijian
authors: W
authors: Wang
mesh_terms: D000180:Acrylic Resins; D002648:Child; D003188:Composite Resins; D003731:Dental Caries / Q000517:prevention & control*; D005899:Glass Ionomer Cements; D006801:Humans; D008963:Molar; D010895:Pit and Fissure Sealants; D012822:Silicon Dioxide; D016037:Single-Blind Method
chemical_list: D000180:Acrylic Resins; D003188:Composite Resins; C493186:Fuji VII; D005899:Glass Ionomer Cements; D010895:Pit and Fissure Sealants; C015897:glass ionomer; C059908:Helioseal; D012822:Silicon Dioxide