title: Copper-catalyzed nucleophilic trifluoromethylation of benzylic chlorides.
abstract: Reactions of primary and secondary benzylic chlorides with trifluoromethyltrimethylsilane in the presence of a catalytic amount of copper(i) thiophene-2-carboxylate (CuTC) have been found to give the corresponding benzylic trifluoromethylated products in good to high yields.
authors: Institute of Engineering Innovation, School of Engineering, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo, 113-8656, Japan. ynishiba@sogo.t.u-tokyo.ac.jp.
authors: Yoshihiro
authors: Y
authors: Miyake
authors: Shin-ichi
authors: S
authors: Ota
authors: Masashi
authors: M
authors: Shibata
authors: Kazunari
authors: K
authors: Nakajima
authors: Yoshiaki
authors: Y
authors: Nishibayashi
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006843:Hydrocarbons, Chlorinated / Q000737:chemistry*; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry*; D008745:Methylation
chemical_list: D006843:Hydrocarbons, Chlorinated; D006845:Hydrocarbons, Fluorinated; D003300:Copper