title: Effects of Fermented Mushroom of Cordyceps sinensis, Rich in Selenium, on Uterine Cervix Cancer.
abstract: The purpose of this study was to investigate the effect of fermented mushroom of Cordyceps sinensis (CS), rich in selenium (Se-CS), on uterine cervical cancer in mice. The methylcholanthrene- (MCA-) induced tumor model was used in this paper. After the mice were administered Se-CS, the animals showed 40% tumor incidence (P < 0.05). Se-CS also enhanced the immune functions. Se-CS treatment showed significant (P < 0.05-0.01) restoration in the level of glutathione content, lipid peroxidation, glutathione peroxidase activity, glutathione reductase activity, catalase activity, Na(+)/K(+)-ATPase activity, and glutathione S transferase activity. This finding suggested that the concomitant use of Se and CS could be a potential therapeutic approach to improve the efficacy of therapy for uterine cervical cancer.
authors: Department of Gynecology and Obstetrics, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an 710061, China.
authors: Jing
authors: J
authors: Ji
authors: Department of Obstetrics, Maternal & Child Health Care Hospital of Shanxi Province, Xi'an 710003, China.
authors: Juan
authors: J
authors: Liu
authors: Department of Gynecology and Obstetrics, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an 710061, China.
authors: Haijuan
authors: H
authors: Liu
authors: Department of Gynecology and Obstetrics, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an 710061, China.
authors: Yueling
authors: Y
authors: Wang