title: Targeted and image-guided photodynamic cancer therapy based on organic nanoparticles with aggregation-induced emission characteristics.
abstract: We report for the first time that organic nanoparticles with photodynamic activity and aggregation-induced emission characteristics are developed for targeted and image-guided photodynamic cancer therapy.
authors: Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore117576. cheliub@nus.edu.sg.
authors: Youyong
authors: Y
authors: Yuan
authors: Guangxue
authors: G
authors: Feng
authors: Wei
authors: W
authors: Qin
authors: Ben Zhong
authors: BZ
authors: Tang
authors: Bin
authors: B
authors: Liu
mesh_terms: D017209:Apoptosis / Q000187:drug effects; D045744:Cell Line, Tumor; D016503:Drug Delivery Systems; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry*; D009369:Neoplasms / Q000188:drug therapy / Q000378:metabolism; D010100:Oxygen / Q000737:chemistry; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use; D017382:Reactive Oxygen Species / Q000737:chemistry
chemical_list: D017319:Photosensitizing Agents; D017382:Reactive Oxygen Species; D010100:Oxygen