title: ACR appropriateness Criteria® advanced stage endometrial cancer.
abstract: OBJECTIVE
  Patients with advanced stage endometrial carcinoma constitute a heterogeneous group of patients with different stages, tumor histologic types, and involved sites. Hysterectomy, bilateral salpingo-ophorectomy, and surgical staging are the cornerstone of surgical management in these patients. The optimal adjuvant therapy is yet to be established. An expert panel was convened to reach consensus on the most appropriate management options in this group of patients.
  
  
  METHODS
  The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed every 3 years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances where evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment.
  
  
  RESULTS
  Four clinical variants were developed to address common scenarios in the management of women with advanced-stage endometrial carcinoma. Group members reached consensus on the appropriateness of specific evaluation and treatment approaches with numerical ratings.
  
  
  CONCLUSIONS
  In combining available medical literature and expert opinions, this manuscript may serve as an aid for other practitioners in the appropriate management of women with advanced-stage endometrial carcinoma.
authors: *Department of Radiation Oncology, Henry Ford Health System, Detroit #University of Michigan Health System, Ann Arbor, MI †University of California San Diego, San Diego, CA **Stanford Cancer Center, Stanford, CA ‡University of Miami, Miami, FL §Indiana University Medical Center, Indianapolis, IN §§Indiana University School of Medicine, Indianapolis, IN (American College of Obstetricians and Gynecologists) ∥Medical College of Wisconsin, Milwaukee, WI ¶University of Texas, MD Anderson Cancer Center, Houston, TX ††Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, MA ‡‡UW Medicine, University of Washington, Seattle, WA †††Fred Hutchinson Cancer Center, University of Washington, Seattle, WA ∥∥University of Maryland School of Medicine, Baltimore, MD (American Society of Clinical Oncology) ¶¶Stritch School of Medicine Loyola University Chicago, Maywood, IL ##University of North Carolina School of Medicine, Chapel Hill, NC ***University of Nebraska Medical Center, Omaha, NE ‡‡‡University of Utah Medical Center, Salt Lake City, UT.
authors: Mohamed A
authors: MA
authors: Elshaikh
authors: Catheryn M
authors: CM
authors: Yashar
authors: Aaron H
authors: AH
authors: Wolfson
authors: Higinia Rosa
authors: HR
authors: Cardenes
authors: Beth
authors: B
authors: Erickson
authors: Anuja
authors: A
authors: Jhingran
authors: Shruti
authors: S
authors: Jolly
authors: Elizabeth
authors: E
authors: Kidd
authors: Larissa J
authors: LJ
authors: Lee
authors: Nina A
authors: NA
authors: Mayr
authors: David
authors: D
authors: Moore
authors: Gautam G
authors: GG
authors: Rao
authors: William
authors: W
authors: Small
authors: Mahesh A
authors: MA
authors: Varia
authors: Andrew O
authors: AO
authors: Wahl
authors: William
authors: W
authors: Yuh
authors: David K
authors: DK
authors: Gaffney
mesh_terms: D017024:Chemotherapy, Adjuvant; D016889:Endometrial Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local; D016879:Salvage Therapy