title: To Evaluate the Accuracy of Saline Infusion Sonohysterography (SIS) for Evaluation of Uterine Cavity Abnormalities in Patients with Abnormal Uterine Bleeding.
abstract: OBJECTIVE
  To evaluate the accuracy of transvaginal sonography (TVS) and saline infusion sonohysterography (SIS) for detection of uterine cavity abnormalities in patients with abnormal uterine bleeding (AUB) taking hysteroscopy as the gold standard.
  
  
  METHODS
  This was a prospective study done in the department of Obstetrics and Gynecology of a tertiary care academic hospital. Sixty premenopausal and postmenopausal women who presented with AUB underwent TVS, SIS, and hysteroscopy. The presence of focal abnormality and the type of abnormality, i.e., polyp, submucous myoma, and endometrial hyperplasia, were noted. The results of TVS and SIS were compared with hysteroscopy.
  
  
  RESULTS
  On hysteroscopy, 76.67 % (n = 46) patients were diagnosed with intra cavity abnormalities. SIS showed sensitivity, specificity, PPV, and NPV of 89.1, 100, 100, and 73.7 %, respectively. In comparison, TVS showed sensitivity, specificity, PPV, and NPV of 43.48, 78.57, 86.96, and 29.73 %, respectively.
  
  
  CONCLUSIONS
  SIS was found to be more sensitive and specific than TVS in detection of intra cavity abnormalities.
authors: Department of Obstetrics and Gynecology PGIMER, Dr. RML Hospital, New Delhi, 110001 India ; J-5/169, Rajouri Garden, New Delhi, 110027 India.
authors: Indu
authors: I
authors: Chawla
authors: Department of Obstetrics and Gynecology PGIMER, Dr. RML Hospital, New Delhi, 110001 India.
authors: Suchita
authors: S
authors: Tripathi
authors: Department of Radiodiagnosis PGIMER, Dr. RML Hospital, New Delhi, 110001 India.
authors: Poonam
authors: P
authors: Vohra
authors: Department of Obstetrics and Gynecology PGIMER, Dr. RML Hospital, New Delhi, 110001 India.
authors: Pushpa
authors: P
authors: Singh
keywords: AUB; Endometrial polyps; Hysteroscopy; SIS; TVS