title: Prospective analysis of the risk factors for falls in lymphoma patients.
abstract: OBJECTIVE
  To explore the risk factors for falls in lymphoma patients receiving chemotherapy.
  
  
  METHODS
  Lymphoma patients (203) who received chemotherapy were prospectively recruited and analyzed. Eligible participants were followed up by weekly telephone contact for 6 months or until the time of a fall or death. Risk factors for falling in lymphoma patients were identified using univariate regression analysis and multivariate binary logistic regression analysis.
  
  
  RESULTS
  Of the 203 cases, 13.3% (27 cases) had a fall during follow-up. Univariate regression analysis showed the following risk factors for falls in lymphoma patients: gender (P = 0.023), Eastern Cooperative Oncology Group (ECOG) performance status score (P < 0.0001), cancer stage (P < 0.0001), extranodal involvement (P = 0.041), serum lactate dehydrogenase (LDH) level (P < 0.0001), revised International Prognostic Index (R-IPI) (P < 0.0001), history of falls (P < 0.0001), gait (P < 0.0001), cognitive condition (P = 0.029) and intravenous catheter placement (P < 0.0001). Multivariate binary logistic regression analysis found four independent factors significantly associated with the risk of falling in lymphoma patients: female gender (P = 0.042), later stage (P = 0.021), R-IPI (P = 0.030), and intravenous catheter placement (P = 0.001).
  
  
  CONCLUSIONS
  Gender, stage, R-IPI, and intravenous catheter placement were independent risk factors for falls in patients with lymphoma. Lymphoma patients with these four risk factors should receive particular attention and fall prevention education to reduce the incidence of falls. The R-IPI may be a new predictor of falling in lymphoma patients and may aid in the management of falls.
authors: Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China; State Key Laboratory of Oncology in South China, Guangzhou, China.
authors: Qiu-Huan
authors: QH
authors: Kong
authors: Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China; State Key Laboratory of Oncology in South China, Guangzhou, China.
authors: Yu
authors: Y
authors: Wang
authors: Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China; State Key Laboratory of Oncology in South China, Guangzhou, China.
authors: Chen-Ge
authors: CG
authors: Song
authors: Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China; State Key Laboratory of Oncology in South China, Guangzhou, China.
authors: Yu-Shan
authors: YS
authors: Liu
authors: Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China; State Key Laboratory of Oncology in South China, Guangzhou, China.
authors: Hui-Ying
authors: HY
authors: Qin
authors: Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China; State Key Laboratory of Oncology in South China, Guangzhou, China.
authors: Yan-Dan
authors: YD
authors: Feng
authors: Department of Lymphoma and Hematology, Hunan Provincial Tumor Hospital, Changsha, Hunan, China; The Affiliated Tumor Hospital of Xiangya Medical School, Central South University, Changsha, Hunan, China. Electronic address: liyajun9@yahoo.com.
authors: Ya-Jun
authors: YJ
authors: Li
mesh_terms: D000058:Accidental Falls / Q000706:statistics & numerical data*; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002406:Catheterization, Peripheral / Q000706:statistics & numerical data; D015984:Causality; D015331:Cohort Studies; D015897:Comorbidity; D004358:Drug Therapy; D064420:Drug-Related Side Effects and Adverse Reactions / Q000453:epidemiology*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008223:Lymphoma / Q000188:drug therapy* / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011379:Prognosis; D011446:Prospective Studies; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D055815:Young Adult
keywords: Falling; Gender; Intravenous catheter placement; Lymphoma patients; Nursing; R-IPI; Risk factors; Stage