title: [Pain in chronic pancreatitis and pancreatic cancer - treatment options].
abstract: Treatment of pain is one of the main pillars of treatment of pancreatic diseases. Abdominal pain is a common and often debilitating symptom in patients with chronic pancreatitis and pancreatic cancer. Treatment involves abstinence from tobacco, alcohol and analgetics and adjunctive agents. Surgical and endoscopic treatment requires careful patient selection based on a detailed analysis of ductal anatomy. The limited possibilities of this therapy are patients without dilatation of the main pancreatic duct. Results of randomized trials suggest that the effect of surgical treatment is sustained over time and more efficient than the endoscopic treatment. Less frequently used options include EUS - assisted celiac plexus blockade, thoracoscopic splanchniectomia or total pancreatectomy with islet cell autotransplantation. These methods are rarely used when all other options have failed and only in carefully selected patients.
authors: Martina
authors: M
authors: Bojková
authors: Pavel
authors: P
authors: Klvaňa
authors: Pavel
authors: P
authors: Svoboda
authors: Tomáš
authors: T
authors: Kupka
authors: Arnošt
authors: A
authors: Martínek
authors: Marian
authors: M
authors: Bojko
authors: Petr
authors: P
authors: Dítě
mesh_terms: D015746:Abdominal Pain / Q000209:etiology* / Q000628:therapy*; D000700:Analgesics / Q000627:therapeutic use; D001340:Autonomic Nerve Block; D006801:Humans; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000150:complications*; D050500:Pancreatitis, Chronic / Q000150:complications*
chemical_list: D000700:Analgesics
keywords: abdominal pain - medical therapy - endoscopy - neurolysis - nociceptive neurons - surgery.