title: Risk factors for hospitalization among children with influenza B infection.
abstract: Data regarding risk factors for hospitalization among children with influenza B infection are limited. We conducted a retrospective study of 184 children with influenza B infection during October 2011 - September 2012 seen at Bamrasnaradura Infectious Diseases Institute, Thailand; clinical and laboratory data were compared between hospitalized and outpatient children. The numbers of hospitalized and outpatient children were 65 (35%) and 119 (65%), respectively. Most children (> 80%) were aged > or = 5 years. The median time from onset of symptoms to starting oseltamivir treatment was significantly longer among hospitalized than outpatient children (3 days vs 2 days, p < 0.05). The significantly more hospitalized children received antibiotics than outpatient children (43% vs 7%, p < 0.05). Complications were more common among hospitalized children than outpatient children (37% vs 2%, p < 0.05). Pneumonia and rhinosinusitis were significantly more common among hospitalized children than outpatient children (p < 0.05). Direct contact history, history of receiving an influenza vaccine, history of a previous influenza infection, body temperature, respiratory symptoms, gastrointestinal symptoms, headache and laboratory findings were not significantly different between the two groups (p > 0.05). In conclusion, delay initiation of antiviral therapy and medical complications (pneumonia and rhinosinusitis) were more common among hospitalized children with influenza B than outpatient children with influenza B in the studied population.
authors: Visal
authors: V
authors: Moolasart
authors: Weerawat
authors: W
authors: Manosuthi
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D002673:Child, Hospitalized; D002675:Child, Preschool; D005260:Female; D006801:Humans; D009981:Influenza B virus / Q000302:isolation & purification*; D007251:Influenza, Human / Q000150:complications* / Q000188:drug therapy / Q000821:virology*; D008297:Male; D053139:Oseltamivir / Q000627:therapeutic use; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents; D000998:Antiviral Agents; D053139:Oseltamivir