title: Recurrent severe anaemia: a rare presentation of parvovirus b19 infection.
abstract: Secondary pure red cell aplasia is usually seen in immunocompromised hosts or patients who have chronic haemolytic anaemia, which is caused by blood transfusion related transmission. The present patient, a 30-year-old immunocompetent female, presented several times with recurrent severe anaemia, over a period of one and half years. Her history, clinical examination and investigations did not reveal any indigenous drug intake, previous blood transfusions, haemolytic disorders, myeloproliferative disorders, pregnancies, autoimmune diseases or thymoma. She was found to have a thalassaemia minor trait, on the basis of which severity and recurrence of anaemia could not be explained, and on further evaluation, she was diagnosed to have acute aplastic crisis caused by Parvovirus B19 induced, acquired pure red cell aplasia. The co- existence of these two haematological disorders in an immunocompetent, non-transfusion dependent individual is rare, which makes our case report unique.
authors: Professor and Head, Department of Medicine, Government Medical College , Amritsar, Punjab, India .
authors: Santokh
authors: S
authors: Singh
authors: Associate Professor, Department of Medicine, Government Medical College , Amritsar, Punjab, India .
authors: Gian
authors: G
authors: Chand
authors: Associate Professor, Departmentof Medicine, Government Medical College , Amritsar, Punjab, India .
authors: Shiv
authors: S
authors: Charan
authors: Junior Resident, Department of Medicine, Government Medical College , Amritsar, Punjab, India .
authors: Sahil
authors: S
authors: Arora
authors: Clinical Associate, Department of Medicine, Government Medical College , Amritsar, Punjab, India .
authors: Parampreet
authors: P
authors: Singh
keywords: Beta thalassemia minor trait; Immunocompetent individual; Non transfusion dependent; Secondary pure red cell aplasia