title: Cancer incidence in people with affective disorder: nationwide cohort study in Taiwan, 1997-2010.
abstract: BACKGROUND
  Cancer is a serious public health problem worldwide, and its relationship with affective disorders is not clear. Aims To investigate alcohol- and tobacco-related cancer risk among patients with affective disorders in a large Taiwanese cohort.
  
  
  METHODS
  Records of newly admitted patients with affective disorders from January 1997 through December 2002 were retrieved from the Psychiatric Inpatient Medical Claims database in Taiwan. Cancers were stratified by site and grouped into tobacco- or alcohol-related cancers. Standardised incidence ratios (SIRs) were calculated to compare the risk of cancer between those with affective disorders and the general population.
  
  
  RESULTS
  Some 10 207 patients with bipolar disorder and 9826 with major depression were included. The risk of cancer was higher in patients with major depression (SIR = 2.01, 95% CI 1.85-2.19) than in those with bipolar disorder (SIR 1.39, 95% CI 1.26-1.53). The elevated cancer risk among individuals ever admitted to hospital for affective disorders was more pronounced in tobacco- and/or alcohol-related cancers.
  
  
  CONCLUSIONS
  Elevated cancer risk was found in patients who had received in-patient care for affective disorders. They require holistic approaches to lifestyle behaviours and associated cancer risks.
authors: Yen-Ni Hung, PhD, School of Gerontology Health Management and Master Program in Long-Term Care, College of Nursing, Taipei Medical University, Department of Nursing, School of Nursing, National Yang-Ming University and Department of Education and Research, Taipei City Hospital, Taipei; Shu-Yu Yang, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei and Graduate Institute of Clinical Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan; Ming-Chyi Huang, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei; For-Wey Lung, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei; Shih-Ku Lin, MD,Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei; Kuan-Yu Chen, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei; Chian-Jue Kuo, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University and Psychiatric Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Ying-Yeh Chen, MD, ScD, Taipei City Psychiatric Center, Taipei City Hospital and Institute of Public Health and Department of Public Health, National Yang-Ming University, Taipei, Taiwan.
authors: Yen-Ni
authors: YN
authors: Hung
authors: Yen-Ni Hung, PhD, School of Gerontology Health Management and Master Program in Long-Term Care, College of Nursing, Taipei Medical University, Department of Nursing, School of Nursing, National Yang-Ming University and Department of Education and Research, Taipei City Hospital, Taipei; Shu-Yu Yang, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei and Graduate Institute of Clinical Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan; Ming-Chyi Huang, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei; For-Wey Lung, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei; Shih-Ku Lin, MD,Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei; Kuan-Yu Chen, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei; Chian-Jue Kuo, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University and Psychiatric Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Ying-Yeh Chen, MD, ScD, Taipei City Psychiatric Center, Taipei City Hospital and Institute of Public Health and Department of Public Health, National Yang-Ming University, Taipei, Taiwan.
authors: Shu-Yu
authors: SY
authors: Yang
authors: Yen-Ni Hung, PhD, School of Gerontology Health Management and Master Program in Long-Term Care, College of Nursing, Taipei Medical University, Department of Nursing, School of Nursing, National Yang-Ming University and Department of Education and Research, Taipei City Hospital, Taipei; Shu-Yu Yang, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei and Graduate Institute of Clinical Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan; Ming-Chyi Huang, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei; For-Wey Lung, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei; Shih-Ku Lin, MD,Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei; Kuan-Yu Chen, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei; Chian-Jue Kuo, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University and Psychiatric Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Ying-Yeh Chen, MD, ScD, Taipei City Psychiatric Center, Taipei City Hospital and Institute of Public Health and Department of Public Health, National Yang-Ming University, Taipei, Taiwan.
authors: Ming-Chyi
authors: MC
authors: Huang
authors: Yen-Ni Hung, PhD, School of Gerontology Health Management and Master Program in Long-Term Care, College of Nursing, Taipei Medical University, Department of Nursing, School of Nursing, National Yang-Ming University and Department of Education and Research, Taipei City Hospital, Taipei; Shu-Yu Yang, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei and Graduate Institute of Clinical Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan; Ming-Chyi Huang, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei; For-Wey Lung, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei; Shih-Ku Lin, MD,Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei; Kuan-Yu Chen, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei; Chian-Jue Kuo, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University and Psychiatric Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Ying-Yeh Chen, MD, ScD, Taipei City Psychiatric Center, Taipei City Hospital and Institute of Public Health and Department of Public Health, National Yang-Ming University, Taipei, Taiwan.
authors: For-Wey
authors: FW
authors: Lung
authors: Yen-Ni Hung, PhD, School of Gerontology Health Management and Master Program in Long-Term Care, College of Nursing, Taipei Medical University, Department of Nursing, School of Nursing, National Yang-Ming University and Department of Education and Research, Taipei City Hospital, Taipei; Shu-Yu Yang, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei and Graduate Institute of Clinical Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan; Ming-Chyi Huang, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei; For-Wey Lung, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei; Shih-Ku Lin, MD,Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei; Kuan-Yu Chen, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei; Chian-Jue Kuo, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University and Psychiatric Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Ying-Yeh Chen, MD, ScD, Taipei City Psychiatric Center, Taipei City Hospital and Institute of Public Health and Department of Public Health, National Yang-Ming University, Taipei, Taiwan.
authors: Shih-Ku
authors: SK
authors: Lin
authors: Yen-Ni Hung, PhD, School of Gerontology Health Management and Master Program in Long-Term Care, College of Nursing, Taipei Medical University, Department of Nursing, School of Nursing, National Yang-Ming University and Department of Education and Research, Taipei City Hospital, Taipei; Shu-Yu Yang, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei and Graduate Institute of Clinical Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan; Ming-Chyi Huang, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei; For-Wey Lung, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei; Shih-Ku Lin, MD,Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei; Kuan-Yu Chen, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei; Chian-Jue Kuo, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University and Psychiatric Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Ying-Yeh Chen, MD, ScD, Taipei City Psychiatric Center, Taipei City Hospital and Institute of Public Health and Department of Public Health, National Yang-Ming University, Taipei, Taiwan.
authors: Kuan-Yu
authors: KY
authors: Chen
authors: Yen-Ni Hung, PhD, School of Gerontology Health Management and Master Program in Long-Term Care, College of Nursing, Taipei Medical University, Department of Nursing, School of Nursing, National Yang-Ming University and Department of Education and Research, Taipei City Hospital, Taipei; Shu-Yu Yang, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei and Graduate Institute of Clinical Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan; Ming-Chyi Huang, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei; For-Wey Lung, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei; Shih-Ku Lin, MD,Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei; Kuan-Yu Chen, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei; Chian-Jue Kuo, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University and Psychiatric Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Ying-Yeh Chen, MD, ScD, Taipei City Psychiatric Center, Taipei City Hospital and Institute of Public Health and Department of Public Health, National Yang-Ming University, Taipei, Taiwan.
authors: Chian-Jue
authors: CJ
authors: Kuo
authors: Yen-Ni Hung, PhD, School of Gerontology Health Management and Master Program in Long-Term Care, College of Nursing, Taipei Medical University, Department of Nursing, School of Nursing, National Yang-Ming University and Department of Education and Research, Taipei City Hospital, Taipei; Shu-Yu Yang, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei and Graduate Institute of Clinical Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan; Ming-Chyi Huang, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei; For-Wey Lung, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei; Shih-Ku Lin, MD,Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei; Kuan-Yu Chen, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei; Chian-Jue Kuo, MD, PhD, Taipei City Psychiatric Center, Taipei City Hospital and Department of Psychiatry, School of Medicine, Taipei Medical University and Psychiatric Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Ying-Yeh Chen, MD, ScD, Taipei City Psychiatric Center, Taipei City Hospital and Institute of Public Health and Department of Public Health, National Yang-Ming University, Taipei, Taiwan.
authors: Ying-Yeh
authors: YY
authors: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D016208:Databases, Factual; D005260:Female; D006306:Health Surveys; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000453:epidemiology*; D009369:Neoplasms / Q000453:epidemiology*; D012306:Risk; D013624:Taiwan / Q000453:epidemiology; D055815:Young Adult