title: GnIH and GnRH expressions in the central nervous system and pituitary of Indian major carp, Labeo rohita during ontogeny: An immunocytochemical study.
abstract: Gonadotropin-releasing hormone (GnRH) is the major hypothalamic neuropeptide stimulating gonadotropin secretion in vertebrates. In 2000, gonadotropin-inhibitory hormone (GnIH) was discovered as a hypothalamic neuropeptide that inhibits gonadotropin secretion in birds. Subsequent studies have shown that GnIH is present in the brain of other vertebrates. We show for the first time GnIH immunoreactivity in the central nervous system and pituitary during development of Indian major carp, Labeo rohita and compare it with the localization of GnRH. GnIH and GnRH immunoreactivities were observed from the olfactory system to spinal cord throughout development. In the brain, both neuropeptides were localized in the telencephalon, diencephalon including the preoptic area and rhombencephalon. The localization of GnIH and GnRH in the pituitary suggests that these neuropeptides are involved in the regulation of pituitary hormones by an autocrine manner during development. In addition, the presence of GnIH and GnRH in several other brain regions including the olfactory system suggests their involvement in the regulation of other physiological functions.
authors: Department of Zoology, RTM Nagpur University, Nagpur 440033, India.
authors: Saikat
authors: S
authors: Biswas
authors: Department of Zoology, RTM Nagpur University, Nagpur 440033, India. Electronic address: agj213@hotmail.com.
authors: Arun G
authors: AG
authors: Jadhao
authors: Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, 81100 Caserta, Italy.
authors: Claudia
authors: C
authors: Pinelli
authors: Department of Zoology, RTM Nagpur University, Nagpur 440033, India.
authors: Nikhil V
authors: NV
authors: Palande
authors: Laboratory of Integrative Brain Sciences, Department of Biology and Center for Medical Life Science, Waseda University, Tokyo 162-8480, Japan.
authors: Kazuyoshi
authors: K
authors: Tsutsui
mesh_terms: D000818:Animals; D002347:Carps / Q000378:metabolism*; D002490:Central Nervous System / Q000378:metabolism*; D007987:Gonadotropin-Releasing Hormone / Q000378:metabolism*; D006062:Gonadotropins / Q000378:metabolism; D007028:Hypothalamic Hormones / Q000378:metabolism* / Q000502:physiology
chemical_list: D006062:Gonadotropins; D007028:Hypothalamic Hormones; D007987:Gonadotropin-Releasing Hormone
keywords: Carp; GnIH; GnRH; Ontogeny; Pituitary