title: Biomimetic strategies for bone repair and regeneration.
abstract: The osseointegration rate of implants is related to their composition and surface roughness. Implant roughness favors both bone anchoring and biomechanical stability. Osteoconductive calcium phosphate (Ca-P) coatings promote bone healing and apposition, leading to the rapid biological fixation of implants. It has been clearly shown in many publications that Ca-P coating accelerates bone formation around the implant. This review discusses two main routes for the manufacturing of polymer-based osteoconductive scaffolds for tissue engineering, namely the incorporation of bioceramic particles in the scaffold and the coating of a scaffold with a thin layer of apatite through a biomimetic process.
authors: Institute of Composite and Biomedical Materials, National Research Council of Italy, P.le Tecchio 80, Naples 80125, Italy. mariagrazia.raucci@cnr.it.
authors: Maria G
authors: MG
authors: Raucci
authors: Institute of Composite and Biomedical Materials, National Research Council of Italy, P.le Tecchio 80, Naples 80125, Italy. vguarino@unina.it.
authors: Vincenzo
authors: V
authors: Guarino
authors: Institute of Composite and Biomedical Materials, National Research Council of Italy, P.le Tecchio 80, Naples 80125, Italy. ambrosio@unina.it.
authors: Luigi
authors: L
authors: Ambrosio