title: [Ovarian teratoma associated with anti-N-methyl-D-aspartate receptor encephalitis: a report of 5 cases and review of the literature].
abstract: OBJECTIVE
  To report the clinical features of ovarian teratoma in patients with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis.
  
  
  METHODS
  The clinical information of five female patients with ovarian teratoma and anti-NMDAR encephalitis in Peking Union Medical College Hospital and Beijing Tiantan Hospital affiliated to Capital Medical University from June 2011 to May 2013 were obtained. Relevant literatures were reviewed.
  
  
  RESULTS
  The initial symptoms varied from respiratory prodromes or emotional incentives before the onset of psychiatric symptoms. Patients always presented with psychosis, bizarre dyskinesia and seizures. Antibodies to NMDAR in serum and cerebrospinal fluid (CSF) were positive; The psychiatric symptoms were dramatically relieved by tumor reception and immunotherapy which occurred in inverse order of symptom development. No evidence of tumor recurrence was observed during a short-time follow-up after the surgery.
  
  
  CONCLUSIONS
  Ovarian teratoma with anti-NMDAR encephalitis always presents with psychiatric symptoms which could be misdiagnosed as psychiatric diseases. Patients respond to tumor resection and immunotherapy.
authors: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital,Beijing 100730, China.
authors: Xingnan
authors: X
authors: Zhou
authors: Email: sundw1118@aliyun.com.
authors: Dawei
authors: D
authors: Sun
authors: Limin
authors: L
authors: Feng
authors: Lei
authors: L
authors: Guo
authors: Haitao
authors: H
authors: Ren
authors: Xiaowei
authors: X
authors: Xue
authors: Zhufeng
authors: Z
authors: Liu
authors: Jinhua
authors: J
authors: Leng
authors: Lan
authors: L
authors: Zhu
authors: Jinghe
authors: J
authors: Lang
mesh_terms: D000328:Adult; D060426:Anti-N-Methyl-D-Aspartate Receptor Encephalitis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D001323:Autoantibodies / Q000097:blood / Q000134:cerebrospinal fluid; D005260:Female; D006801:Humans; D007167:Immunotherapy; D010535:Laparoscopy; D010051:Ovarian Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000628:therapy; D010053:Ovary / Q000601:surgery; D016194:Receptors, N-Methyl-D-Aspartate / Q000276:immunology*; D013724:Teratoma / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000628:therapy; D055815:Young Adult; D005719:gamma-Globulins / Q000627:therapeutic use
chemical_list: D001323:Autoantibodies; D016194:Receptors, N-Methyl-D-Aspartate; D005719:gamma-Globulins