title: Asymmetric epoxidation of olefins with hydrogen peroxide by an in situ-formed manganese complex.
abstract: Asymmetric epoxidation of a variety of cis, trans, terminal, and trisubstituted olefins in excellent yields (up to 94%) and enantioselectivities (>99% ee) by an in situ-formed manganese complex using H2O2 has been developed. A relationship between the hydrophobicity of the catalyst imposed by ligand and the catalytic activity has been observed. The influence of the amount and identity of the acid additive was examined, and improved enantioselectivities were achieved through the use of a catalytic amount of a carboxylic acid additive.
authors: Dalian Institute of Chemical Physics, Chinese Academy of Sciences , Dalian 116023, People's Republic of China.
authors: Wen
authors: W
authors: Dai
authors: Sensen
authors: S
authors: Shang
authors: Bo
authors: B
authors: Chen
authors: Guosong
authors: G
authors: Li
authors: Lianyue
authors: L
authors: Wang
authors: Lanhui
authors: L
authors: Ren
authors: Shuang
authors: S
authors: Gao
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D004852:Epoxy Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D006861:Hydrogen Peroxide / Q000737:chemistry*; D008345:Manganese / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D004852:Epoxy Compounds; D009942:Organometallic Compounds; D008345:Manganese; D006861:Hydrogen Peroxide