title: Maxillary sporadic Burkitt's lymphoma associated with neuro-orbital involvement in an Indian male.
abstract: Burkitt's lymphoma (BL) is the fastest growing malignancy of the lymphoreticular system to affect humans and has a potential ability to double in size every day. A case of maxillary sporadic BL (sBL) associated with neuro-orbital involvement in an Indian male is presented. sBL initially presented as maxillary swelling with no obvious dental and periodontal changes. Histological specimen from incisional biopsy revealed a round cell malignant tumor and immunohistochemistry reactions favored nonHodgkin's lymphoma consistent with BL. Four weeks later, patient presented with orbital involvement as diplopia, sixth cranial nerve palsy, and medial rectus palsy. Chemotherapy regimen according to LMB 89 protocol was started. During chemotherapy regimen patient showed bradycardia and Babinski response, suggestive of central nervous system involvement. sBL associated with orbital involvement is extremely rare and only seven cases have been reported. Our case showed unusual presentation; despite the aggressive tumor did not show any common clinical, radiological, and hematological findings. We also discussed the role of oral medicine specialist, importance of early diagnosis, and prompt referral in management of maxillary sBL.
authors: Department of Oral Medicine and Radiology, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, India.
authors: Rakesh Kumar
authors: RK
authors: Manne
authors: Department of Oral Medicine and Radiology, Government Dental College, RIMS, Kadapa, Andhra Pradesh, India.
authors: Chandra Sekhar
authors: CS
authors: Madu
authors: Department of Oral Medicine and Radiology, Meghana Institute of Dental Sciences, Nizamabad, Andhra Pradesh, India.
authors: Harsh Vardhan
authors: HV
authors: Talla
keywords: Burkitt's lymphoma; maxilla; nonHodgkin lymphomas; orbit