title: Enantioselective hydrogenation of α,β-disubstituted nitroalkenes.
abstract: The first highly chemo- and enantioselective hydrogenation of α,β-disubstituted nitroalkenes was accomplished with rhodium/JosiPhos-J2 as a catalyst, with the yield and enantioselectivity of up to 95% and 94%, respectively. The α-chiral nitroalkanes will provide an entry to valuable chiral amphetamines which are otherwise not so easily accessed.
authors: College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, P.R. China. saintkun001@njau.edu.cn.
authors: Shengkun
authors: S
authors: Li
authors: Kexuan
authors: K
authors: Huang
authors: Xumu
authors: X
authors: Zhang
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D006865:Hydrogenation; D009574:Nitro Compounds / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry; D012238:Rhodium / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D009574:Nitro Compounds; D010720:Phosphines; D012238:Rhodium