title: Antibacterial characteristics of heated scallop-shell nano-particles.
abstract: Heated scallop-shell (HSS) nano-particles, prepared using a wet grinding mill, and microparticles were examined for their antibacterial activity against vegetative bacterial cells and spores. The median diameters of the nano-particles and micro-particles were approximately 20 nm and 30 µm, respectively. The antibacterial activity of HSS against Escherichia coli increased with an increase in concentration, regardless of particle size; however, the antibacterial activity of the nano-particles was much higher than that of micro-particles. The sporicidal activity of the nano-particles was also much higher than that of micro-particles, with HSS nano-particles able to kill Bacillus subtilis spores. A reduction of more than three orders of magnitude for B. subtilis spores was confirmed following a 30 min treatment at 5 mg/ml and 60℃, showing that the combination of HSS nano-particle treatment with mild heating was particularly effective for controlling bacterial spores.
authors: Faculty of Applied Bioscience, Kanagawa Institute of Technology.
authors: Takashi
authors: T
authors: Watanabe
authors: Riku
authors: R
authors: Fujimoto
authors: Jun
authors: J
authors: Sawai
authors: Mikio
authors: M
authors: Kikuchi
authors: Shinya
authors: S
authors: Yahata
authors: Susumu
authors: S
authors: Satoh
mesh_terms: D060105:Animal Shells / Q000737:chemistry*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects* / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004926:Escherichia coli / Q000187:drug effects* / Q000502:physiology; D006358:Hot Temperature; D008826:Microbial Sensitivity Tests; D053758:Nanoparticles / Q000737:chemistry / Q000633:toxicity*; D010316:Particle Size; D049897:Pectinidae / Q000737:chemistry*; D011208:Powders; D013171:Spores, Bacterial / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D011208:Powders