title: Flavanones fromMiconia prasina.
abstract: A glycosidic flavanone miconioside C (1) has been isolated from the methanolic extract of the stems ofMiconia prasina, together with 7-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranosylmatteucinol (2), miconioside B (3), matteucinol (4), farrerol (5) and desmethoxymatteucinol (6). Their structures were mainly established by extensive NMR studies (1H NMR,13C NMR, DEPT,1H-1H COSY, HSQC, HMBC) and mass spectrometry. The compounds1-3were evaluated forin vitrobinding assays using cannabinoid receptors (CB1 and CB2).
authors: Department of Medicinal Chemistry, The University of Mississippi, University, MS 38677, USA.
authors: Amer H
authors: AH
authors: Tarawneh
authors: Department of Medicinal Chemistry, The University of Mississippi, University, MS 38677, USA.
authors: Francisco
authors: F
authors: León
authors: National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.
authors: Mohammed A
authors: MA
authors: Ibrahim
authors: Department of Medicinal Chemistry, The University of Mississippi, University, MS 38677, USA.
authors: Sara
authors: S
authors: Pettaway
authors: Department of Medicinal Chemistry, The University of Mississippi, University, MS 38677, USA ; National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.
authors: Christopher R
authors: CR
authors: McCurdy
authors: Department of Medicinal Chemistry, The University of Mississippi, University, MS 38677, USA ; National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.
authors: Stephen J
authors: SJ
authors: Cutler
keywords: Melastomataceae; Miconia prasina; cannabinoids receptors; flavanone; flavanone glycoside