title: Preliminary experiments to quantify liquid movement under mimetic vocal fold vibrational forces.
abstract: Hydration of vocal fold tissues is essential for self-sustained oscillation. Normal regulatory processes of liquid transport to and from the vocal folds would be expected through the autonomic systems, but the possibility exists that liquid movement may occur locally due to vibrational pressures. Such movement may cause regions of lower or higher concentrations of liquid viscosity and therewith changes in phonation threshold pressure. Hyaluronic acid, a glycosaminoglycan that attracts large quantities of free water, may be a key molecule for transporting or localizing liquids. Some preliminary experiments are reported in which attempts were made to move low-concentration HA liquids with vibration. None of the experiments was conclusive, but collectively they lay some groundwork for future explorations.
authors: Department of Communication Sciences and Disorders, The University of Iowa , Iowa City, IA , USA.
authors: Ingo R
authors: IR
authors: Titze
authors: Sarah
authors: S
authors: Klemuk
authors: Xiaoying
authors: X
authors: Lu
mesh_terms: D001696:Biomechanical Phenomena; D006801:Humans; D006820:Hyaluronic Acid / Q000737:chemistry*; D008954:Models, Biological; D008956:Models, Chemical; D009038:Motion; D010699:Phonation; D012212:Rheology; D013314:Stress, Mechanical; D013997:Time Factors; D014732:Vibration; D014783:Viscosity; D014827:Vocal Cords / Q000502:physiology*; D014867:Water / Q000737:chemistry*
chemical_list: D014867:Water; D006820:Hyaluronic Acid
keywords: Fluid transport; hyaluronic acid; hydration; threshold pressure; vocal fold vibration