title: Designing a wearable navigation system for image-guided cancer resection surgery.
abstract: A wearable surgical navigation system is developed for intraoperative imaging of surgical margin in cancer resection surgery. The system consists of an excitation light source, a monochromatic CCD camera, a host computer, and a wearable headset unit in either of the following two modes: head-mounted display (HMD) and Google glass. In the HMD mode, a CMOS camera is installed on a personal cinema system to capture the surgical scene in real-time and transmit the image to the host computer through a USB port. In the Google glass mode, a wireless connection is established between the glass and the host computer for image acquisition and data transport tasks. A software program is written in Python to call OpenCV functions for image calibration, co-registration, fusion, and display with augmented reality. The imaging performance of the surgical navigation system is characterized in a tumor simulating phantom. Image-guided surgical resection is demonstrated in an ex vivo tissue model. Surgical margins identified by the wearable navigation system are co-incident with those acquired by a standard small animal imaging system, indicating the technical feasibility for intraoperative surgical margin detection. The proposed surgical navigation system combines the sensitivity and specificity of a fluorescence imaging system and the mobility of a wearable goggle. It can be potentially used by a surgeon to identify the residual tumor foci and reduce the risk of recurrent diseases without interfering with the regular resection procedure.
authors: School of Engineering Science, University of Science and Technology of China, Hefei, China.
authors: Pengfei
authors: P
authors: Shao
authors: Houzhu
authors: H
authors: Ding
authors: Jinkun
authors: J
authors: Wang
authors: Peng
authors: P
authors: Liu
authors: Qiang
authors: Q
authors: Ling
authors: Jiayu
authors: J
authors: Chen
authors: Junbin
authors: J
authors: Xu
authors: Shiwu
authors: S
authors: Zhang
authors: Ronald
authors: R
authors: Xu
mesh_terms: D004867:Equipment Design; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D009369:Neoplasms / Q000601:surgery*; D012984:Software; D025321:Surgery, Computer-Assisted / Q000295:instrumentation*; D059015:Wireless Technology