title: Observations of TCRVβ Gene Expression in Rats with Dampness Syndrome.
abstract: Environmental dampness is one factor which can cause human diseases. The effects of exposure to humidity on human immune function are diverse and numerous. In the theory of traditional Chinese medicine (TCM), dampness is defined as one of the major pathogenic factors in the human body. It is divided into "external dampness" and "internal dampness." However the molecular mechanism leading to humidity-induced immunosuppression is obscure. In the present study, we investigated the expression of the T-cell antigen receptor variable β (TCRVβ) subfamilies in rats which were fed in different humid environment. And the expression levels of the TCRVβ subfamilies were detected using FQ-PCR. We found that the dampness might reduce the immunological recognition function of rats. And the obstruction of the immunological recognition function might be caused by internal dampness rather than external dampness.
authors: Department of Traditional Chinese Medicine,The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China.
authors: Yan
authors: Y
authors: Chen
authors: Department of Traditional Chinese Medicine,The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China.
authors: Bao-Guo
authors: BG
authors: Sun
authors: Department of Traditional Chinese Medicine,The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China.
authors: Shi-Jun
authors: SJ
authors: Zhang
authors: Department of Traditional Chinese Medicine,The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China.
authors: Ze-Xiong
authors: ZX
authors: Chen
authors: Department of Traditional Chinese Medicine,The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China.
authors: Carlini Fan
authors: CF
authors: Hardi
authors: Department of Traditional Chinese Medicine,The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China.
authors: Ting
authors: T
authors: Xiang