title: Genome scale cytometry: High content analysis for high throughput RNAi phenotype profiling.
abstract: The combination of RNAi-mediated knockdown of gene expression and high content screening (HCS) allows the determination of the contribution of single genes to a variety of cellular effects varying between growth and survival to subtle alterations in cellular morphology and phenotype. This review examines the current status of research in combining these tools.:
authors: Cancer Drug Development Laboratory, Translational Genomics Research Institute, 20, Firstfield Rd, Gaithersburg, MD 20878, USA. Electronic address:devans@tgen.org.
authors: David M
authors: DM
authors: Evans
authors: Cancer Drug Development Laboratory, Translational Genomics Research Institute, 20, Firstfield Rd, Gaithersburg, MD 20878, USA.
authors: David O
authors: DO
authors: Azorsa
authors: Cancer Drug Development Laboratory, Translational Genomics Research Institute, 20, Firstfield Rd, Gaithersburg, MD 20878, USA.
authors: Spyro
authors: S
authors: Mousses