title: Neurophysiological and behavioral responses of gypsy moth larvae to insect repellents: DEET, IR3535, and picaridin.
abstract: The interactions between insect repellents and the olfactory system have been widely studied, however relatively little is known about the effects of repellents on the gustatory system of insects. In this study, we show that the gustatory receptor neuron (GRN) located in the medial styloconic sensilla on the maxillary palps of gypsy moth larvae, and known to be sensitive to feeding deterrents, also responds to the insect repellents DEET, IR3535, and picaridin. These repellents did not elicit responses in the lateral styloconic sensilla. Moreover, behavioral studies demonstrated that each repellent deterred feeding. This is the first study to show perception of insect repellents by the gustatory system of a lepidopteran larva and suggests that detection of a range of bitter or aversive compounds may be a broadly conserved feature among insects.
authors: Biological Sciences Department, Insect Morphology and Physiology Lab, Towson University, Towson, Maryland, United States of America.
authors: Jillian L
authors: JL
authors: Sanford
authors: Biological Sciences Department, Insect Morphology and Physiology Lab, Towson University, Towson, Maryland, United States of America.
authors: Sharon A
authors: SA
authors: Barski
authors: Biological Sciences Department, Insect Morphology and Physiology Lab, Towson University, Towson, Maryland, United States of America.
authors: Christina M
authors: CM
authors: Seen
authors: United States Department of Agriculture, Agricultural Research Service, Henry A. Wallace Beltsville Agricultural Research Center, Invasive Insect Biocontrol and Behavior Laboratory, Beltsville, Maryland, United States of America.
authors: Joseph C
authors: JC
authors: Dickens
authors: Biological Sciences Department, Insect Morphology and Physiology Lab, Towson University, Towson, Maryland, United States of America.
authors: Vonnie D C
authors: VD
authors: Shields
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects* / Q000502:physiology; D003671:DEET / Q000494:pharmacology*; D007302:Insect Repellents / Q000494:pharmacology*; D007814:Larva; D009036:Moths / Q000502:physiology*; D010880:Piperidines / Q000494:pharmacology*; D011422:Propionates / Q000494:pharmacology*
chemical_list: D007302:Insect Repellents; D010880:Piperidines; D011422:Propionates; D003671:DEET; C462400:ethyl-3-(N-n-butyl-N-acetyl)aminopropionate; C483506:picaridin