title: Establishing a quality control program: ensuring safety from contamination for recycled metered-dose inhalers.
abstract: BACKGROUND
  Recycling metered-dose inhalers (MDIs) is an effective method to conserve medications resulting in significant cost savings to the hospital. A noted limitation in some reports is the potential for cross-contamination.
  
  
  OBJECTIVE
  To implement a quality control program to monitor and validate the safety of recycled MDIs for institutional reuse.
  
  
  METHODS
  A quality control program was conducted from December 2012 to May 2013. At a 257-bed acute care facility, MDIs are administered to a single patient using a patient-specific valved holding chamber and then returned to the pharmacy for cleaning with 70% isopropyl alcohol prior to re-dispensing to a new patient. Ten percent of MDIs from 3 categories were categorized: prior to pharmacy cleaning, after pharmacy cleaning, and new/unused control group each month. The mouthpiece and canister spray tip from each MDI were tested. Any bacterial growth was documented. A secondary test was conducted to ensure that artificially contaminated MDIs could be cleaned with current cleaning procedures. Cost savings measures were also quantified.
  
  
  RESULTS
  There was no bacterial growth on the 17 recycled MDIs cultured prior to the cleaning process. Bacteria did not grow on any of the 33 recycled MDIs cleaned with 70% isopropyl alcohol. Likewise, in the control group of 33 new/unused control MDIs, there was no bacterial growth. No bacteria growth was found after cleaning each artificially contaminated MDI. Total drug cost savings during the study period was approximately $130,000.
  
  
  CONCLUSIONS
  Establishing a strict quality control program is paramount to validating a safe and effective recycled MDI procedure.
authors: Pharmacist, Saint Elizabeth Regional Medical Center , Lincoln, Nebraska .
authors: Jenny
authors: J
authors: Liou
authors: Pharmacist, Saint Elizabeth Regional Medical Center , Lincoln, Nebraska .
authors: Kurt
authors: K
authors: Clyne
authors: Microbiology Team Lead, Saint Elizabeth Regional Medical Center , Lincoln, Nebraska .
authors: Donnet
authors: D
authors: Knapp
authors: Director of Cardiopulmonary, Saint Elizabeth Regional Medical Center , Lincoln, Nebraska .
authors: Jay
authors: J
authors: Snyder
keywords: cost savings; hospital pharmacy service; metered-dose inhalers; quality control