title: 25-gauge transconjunctival diagnostic vitrectomy in suspected cases of intraocular lymphoma: a case series and review of the literature.
abstract: OBJECTIVE
  To report the cytology results of 25-gauge transconjunctival (25G-TSV) diagnostic vitrectomy in cases suspicious for intraocular lymphoma (IOL), and compare the results to those reported in the literature.
  
  
  METHODS
  Clinical and cytopathological records of 18 vitreous biopsy specimens obtained via 25G-TSV diagnostic vitrectomy in 12 patients suspicious for IOL were reviewed retrospectively. A review of the literature in regards to the diagnostic yields of vitreous specimens obtained via 25-gauge and 20-gauge diagnostic vitrectomy in suspected cases of IOL was performed.
  
  
  RESULTS
  Eighteen eyes from 12 patients with clinical suspicion of IOL underwent diagnostic 25G-TSV. The cytopathological investigations demonstrated IOL in 15 eyes (83.3%). Vitreous analysis was non-diagnostic in 3 eyes (16.7%).
  
  
  CONCLUSIONS
  Twenty-five-gauge diagnostic vitrectomy yields adequate sample for cytological evaluation of the vitreous in cases suspicious for IOL. The diagnostic results of the 25G-TSV in the current study are superior to those reported for 20-gauge vitrectomy but equivalent to those reported for 25G-TSV in the published literature.
authors: Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran 1666663111, Iran.
authors: Mozhgan Rezaei
authors: MR
authors: Kanavi
authors: Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran 1666663111, Iran.
authors: Masoud
authors: M
authors: Soheilian
authors: Central Eye Bank of Iran, Tehran 1968876711, Iran.
authors: Sayed Bagher
authors: SB
authors: Hosseini
authors: Cornea Service, Wills Eye Hospital, Philadelpheia 19107, USA.
authors: Amir A
authors: AA
authors: Azari
keywords: 20-gauge vitrectomy; 25-gauge vitrectomy; intraocular lymphoma