title: Lung recruitment strategies and surfactant in neonatal intensive care unit.
abstract: Several studies in the lamb model have shown that hyperinflation of the lungs early in life may cause a blunted response to surfactant with signs of lung injury and any attempt to recruit lung volume in the surfactant deficient preterm infant by large lung inflations at birth should be potentially dangerous. As regards the situation when surfactant is given later, as rescue treatment for established RDS, the evidence for a clinically beneficial effect of a recruitment maneuver is yet insufficient and, hopefully, future studies will gather more data on this aspect.
authors: . vento@rm.unicatt.it.
authors: G
authors: G
authors: Vento
authors: M
authors: M
authors: Tana
authors: C
authors: C
authors: Tirone
authors: C
authors: C
authors: Aurilia
authors: A
authors: A
authors: Lio
authors: C
authors: C
authors: Ricci
authors: A
authors: A
authors: Gambacorta
authors: C
authors: C
authors: Romagnoli
mesh_terms: D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007363:Intensive Care Units, Neonatal; D007442:Intubation, Intratracheal; D011247:Pregnancy; D011663:Pulmonary Surfactants / Q000494:pharmacology*; D012121:Respiration, Artificial / Q000379:methods; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*; D012151:Resuscitation / Q000379:methods*; D013501:Surface-Active Agents / Q000494:pharmacology
chemical_list: D011663:Pulmonary Surfactants; D013501:Surface-Active Agents