title: Enhanced infrared neural stimulation using localized surface plasmon resonance of gold nanorods.
abstract: An advanced optical activation of neural tissues is demonstrated using pulsed infrared light and plasmonic gold nanorods. Photothermal effect localized in plasma membrane triggers action potentials of in vivo neural tissues. Compared with conventional infrared stimulation, the suggested method can increase a neural responsivity and lower a threshold stimulation level significantly, thereby reducing a requisite radiant exposure and the concern of tissue damage.
authors: Department of Electrical and Computer Engineering, Seoul National University, Seoul, 151-744, Republic of Korea.
authors: Kyungsik
authors: K
authors: Eom
authors: Jinhyung
authors: J
authors: Kim
authors: Jong Min
authors: JM
authors: Choi
authors: Taekyeong
authors: T
authors: Kang
authors: Jin Woo
authors: JW
authors: Chang
authors: Kyung Min
authors: KM
authors: Byun
authors: Sang Beom
authors: SB
authors: Jun
authors: Sung June
authors: SJ
authors: Kim
mesh_terms: D000200:Action Potentials; D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D006046:Gold / Q000737:chemistry*; D007834:Lasers; D008297:Male; D053768:Metal Nanoparticles / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D036103:Nanotechnology; D043942:Nanotubes / Q000737:chemistry*; D009474:Neurons / Q000378:metabolism / Q000473:pathology*; D055095:Optics and Photonics; D010777:Photochemistry; D051381:Rats; D017207:Rats, Sprague-Dawley; D013055:Spectrophotometry, Infrared; D020349:Surface Plasmon Resonance
chemical_list: D006046:Gold
keywords: gold nanoparticles; infrared neural stimulation; photothermal effect; surface plasmon resonance