title: Esophageal intramucosal hematoma after peripheral blood stem cell transplantation: case report and review of literature.
abstract: Esophageal complications occur after hematopoietic stem cell transplantation (HSCT). There are, however, only limited reports on the etiology or management of esophageal complications. Here, we report the occurrence of intramucosal hematoma presenting continuous esophageal hemorrhage in a 34 year-old man following the second peripheral blood stem cell transplantation for acute myeloid leukemia. His hematemesis started 2 months after HSCT and was repeated in supportive care. On day 156, he underwent total esophagectomy as a result of uncontrollable massive hematemesis. Histopathological testings of the resected esophagus confirmed intramucosal hematoma as a cause of hematemesis. This case highlights intramucosal hematoma as one of the important etiologies of esophageal complications following HSCT.
authors: Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo Tokyo, Japan.
authors: Takashi
authors: T
authors: Kobayashi
authors: Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo Tokyo, Japan.
authors: Sachiko
authors: S
authors: Seo
authors: Department of Pathology, Graduate School of Medicine, The University of Tokyo Tokyo, Japan.
authors: Shigeki
authors: S
authors: Morita
authors: Department of Pathology, Graduate School of Medicine, The University of Tokyo Tokyo, Japan.
authors: Akiteru
authors: A
authors: Goto
authors: Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo Tokyo, Japan.
authors: Akiko
authors: A
authors: Masuda
authors: Department of Gastrointestinal Surgery, The University of Tokyo Hospital Tokyo, Japan.
authors: Nobuyuki
authors: N
authors: Shimizu
authors: Department of Gastrointestinal Surgery, The University of Tokyo Hospital Tokyo, Japan.
authors: Masato
authors: M
authors: Nishida
authors: Department of Gastrointestinal Surgery, The University of Tokyo Hospital Tokyo, Japan.
authors: Souya
authors: S
authors: Nunobe
authors: Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo Tokyo, Japan.
authors: Motoshi
authors: M
authors: Ichikawa
authors: Department of Pathology, Graduate School of Medicine, The University of Tokyo Tokyo, Japan.
authors: Yutaka
authors: Y
authors: Takazawa
authors: Department of Gastrointestinal Surgery, The University of Tokyo Hospital Tokyo, Japan.
authors: Yasuyuki
authors: Y
authors: Seto
authors: Department of Pathology, Graduate School of Medicine, The University of Tokyo Tokyo, Japan.
authors: Masashi
authors: M
authors: Fukayama
authors: Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo Tokyo, Japan.
authors: Mineo
authors: M
authors: Kurokawa
mesh_terms: D000328:Adult; D001706:Biopsy; D004935:Esophageal Diseases / Q000175:diagnosis / Q000209:etiology*; D016629:Esophagectomy; D004945:Esophagoscopy; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D006396:Hematemesis / Q000209:etiology; D006406:Hematoma / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000601:surgery*; D008297:Male; D036102:Peripheral Blood Stem Cell Transplantation / Q000009:adverse effects*; D012086:Reoperation; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: Esophageal hemorrhage; esophagectomy; hematopoietic stem cell transplantation; intramucosal hematoma