title: Can the period of postnatal codevelopment of the rubrospinal and corticospinal systems provide new insights into refinement of limb movement?
abstract: The corticospinal and the rubrospinal tracts are thought to synergistically contribute to the limb control during motor development. Williams et al. (J Neurosci 34: 4432-4441, 2014) demonstrate that the postnatal maturation of red nucleus motor map and the rubrospinal tract develops earlier than the corticospinal tract, to support early forelimb control. They have two distinct phases of maturation; a "precorticospinal" phase characterized by development of the rubrospinal system, and a "cocorticospinal" phase where they overlap with corticospinal development.
authors: Department of Biomedical Engineering, University of Southern California, Los Angeles, California; bertucco@usc.edu.
authors: Matteo
authors: M
authors: Bertucco
authors: Department of Orthopaedic Surgery, University of California; and Department of Veterans Affairs Medical Center, San Diego, California.
authors: Sudarshan
authors: S
authors: Dayanidhi
mesh_terms: D000818:Animals; D005260:Female; D008297:Male; D009044:Motor Cortex / Q000502:physiology*; D009048:Motor Skills / Q000502:physiology*; D009068:Movement / Q000502:physiology*; D012012:Red Nucleus / Q000502:physiology*; D013116:Spinal Cord / Q000502:physiology*
keywords: corticospinal; limb motor control; motor development; rubrospinal