title: The role of bioinformatics in target validation.
abstract: Bioinformatics is being increasingly used to support target validation by providing functionally predictive information mined from databases and experimental datasets using a variety of computational tools. The predictive power of these complementary approaches is strongest when information from several techniques is combined, including experimental confirmation of predictions. The aim of this review is to highlight and discuss the key approaches available in this rapidly developing area to facilitate selection of the appropriate tools and databases.:
authors: Novartis Institutes for Biomedical Research, Respiratory Disease Area, Horsham, West Sussex, UK RH125AB. Electronic address:paul.whittaker@pharma.novartis.com.
authors: Paul A
authors: PA
authors: Whittaker