title: Aortic stenosis and coronary artery disease: what do we know? What don't we know? A comprehensive review of the literature with proposed treatment algorithms.
abstract: Aortic valve stenosis is the most common form of valvular heart disease in the elderly population and occurs frequently in conjunction with coronary artery disease. The standard treatment option for patients with these two conditions has been surgical aortic valve replacement and coronary artery bypass grafting. The arrival of transcatheter aortic valve replacement has considerably shifted the treatment paradigms. Nevertheless, a lot of questions remain unanswered regarding the management of coronary artery disease in the setting of the transcatheter options for severe aortic stenosis. This article includes a comprehensive review of the literature and seeks to describe the actual knowledge on the topic of aortic stenosis and concomitant coronary artery disease.
authors: Columbia University Medical Center, New York, NY, USA Cardiovascular Research Foundation, New York, NY, USA Quebec Heart and Lung Institute, Quebec, Canada jm.paradis@criucpq.ulaval.ca.
authors: Jean-Michel
authors: JM
authors: Paradis
authors: Columbia University Medical Center, New York, NY, USA.
authors: Justin
authors: J
authors: Fried
authors: Columbia University Medical Center, New York, NY, USA.
authors: Tamim
authors: T
authors: Nazif
authors: Columbia University Medical Center, New York, NY, USA Cardiovascular Research Foundation, New York, NY, USA.
authors: Ajay
authors: A
authors: Kirtane
authors: Columbia University Medical Center, New York, NY, USA.
authors: Kishore
authors: K
authors: Harjai
authors: Columbia University Medical Center, New York, NY, USA.
authors: Omar
authors: O
authors: Khalique
authors: Columbia University Medical Center, New York, NY, USA.
authors: Kendra
authors: K
authors: Grubb
authors: Columbia University Medical Center, New York, NY, USA.
authors: Isaac
authors: I
authors: George
authors: Columbia University Medical Center, New York, NY, USA.
authors: Rebecca
authors: R
authors: Hahn
authors: Columbia University Medical Center, New York, NY, USA.
authors: Mathew
authors: M
authors: Williams
authors: Columbia University Medical Center, New York, NY, USA Cardiovascular Research Foundation, New York, NY, USA.
authors: Martin B
authors: MB
authors: Leon
authors: Columbia University Medical Center, New York, NY, USA.
authors: Susheel
authors: S
authors: Kodali
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D001024:Aortic Valve Stenosis / Q000150:complications* / Q000601:surgery; D003131:Combined Modality Therapy; D003324:Coronary Artery Disease / Q000150:complications* / Q000601:surgery; D003326:Coronary Circulation / Q000502:physiology; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology; D062645:Percutaneous Coronary Intervention; D011183:Postoperative Complications / Q000209:etiology; D061665:Time-to-Treatment; D065467:Transcatheter Aortic Valve Replacement; D016896:Treatment Outcome; D061205:Vascular Calcification / Q000150:complications
keywords: Aortic stenosis; Coronary artery disease; Percutaneous coronary intervention; Surgical aortic valve replacement; Transcatheter aortic valve replacement