title: Enhancing upconversion luminescence of NaYF4:Yb/Er nanocrystals by Mo(3+) doping and their application in bioimaging.
abstract: Enhancement of upconversion luminescence is imperative for the applications of upconversion nanocrystals (UCNs). In this work, we investigated the upconversion luminescence enhancement of NaYF4:Yb/Er by Mo(3+) ion doping. It was found that the upconversion luminescence intensities of the green and red emissions of UCNs co-doped with 10 mol% Mo(3+) ions were enhanced by 6 and 8 times, respectively. This enhancement offers a potential increase in the overall detectability of upconversion nanocrystals. HeLa cell imaging using NaYF4:Yb/Er/Mo as luminescent probes showed bright upconversion fluorescence. Moreover, the Mo(3+) doping endowed the UCNs with excellent paramagnetic behavior. It is expected that the as-prepared UCNs with a high upconversion luminescence and excellent paramagnetic properties could be promising bi-functional nanoprobes for sensitive multi-modal bioimaging and other optical applications.
authors: School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.
authors: Dongguang
authors: D
authors: Yin
authors: Chengcheng
authors: C
authors: Wang
authors: Juan
authors: J
authors: Ouyang
authors: Kailin
authors: K
authors: Song
authors: Bing
authors: B
authors: Liu
authors: Xianzhang
authors: X
authors: Cao
authors: Lu
authors: L
authors: Zhang
authors: Yanlin
authors: Y
authors: Han
authors: Xie
authors: X
authors: Long
authors: Minghong
authors: M
authors: Wu
mesh_terms: D002470:Cell Survival / Q000187:drug effects; D002951:Citrates / Q000737:chemistry; D004871:Erbium / Q000737:chemistry* / Q000494:pharmacology; D005456:Fluorescent Dyes / Q000737:chemistry* / Q000494:pharmacology; D005459:Fluorides / Q000737:chemistry* / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D049449:Luminescence; D018613:Microscopy, Confocal; D046529:Microscopy, Electron, Transmission; D008982:Molybdenum / Q000737:chemistry* / Q000494:pharmacology; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D000077559:Sodium Citrate; D014961:X-Ray Diffraction; D015018:Ytterbium / Q000737:chemistry* / Q000494:pharmacology; D015019:Yttrium / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D002951:Citrates; D005456:Fluorescent Dyes; C525362:sodium yttriumtetrafluoride; D000077559:Sodium Citrate; D015019:Yttrium; D004871:Erbium; D008982:Molybdenum; D015018:Ytterbium; D005459:Fluorides