title: Endoscopic interventions for necrotizing pancreatitis.
abstract: Interventions for necrotizing pancreatitis have undergone a paradigm shift away from open surgical necrosectomy and toward minimally invasive techniques, with endoscopic transmural drainage (ETD) and necrosectomy emerging as principle forms of treatment. Recent multicenter studies, randomized trials, evidence-based guidelines, and consensus statements have endorsed the safety and efficacy of endoscopic and other minimally invasive techniques for the treatment of walled-off necrosis. A comprehensive review of indications, standard and novel approaches, outcomes, complications, and controversies regarding ETD and necrosectomy is presented. Given the inherent challenges and associated risks, endoscopic techniques for the management of necrotizing pancreatitis should be performed at specialized multidisciplinary centers by expert endoscopists well versed in the management of necrotizing pancreatitis.
authors: Division of Gastroenterology, University of Minnesota, Minneapolis, Minnesota, USA.
authors: Guru
authors: G
authors: Trikudanathan
authors: Division of Gastroenterology, University of Minnesota, Minneapolis, Minnesota, USA.
authors: Rajeev
authors: R
authors: Attam
authors: Division of Gastroenterology, University of Minnesota, Minneapolis, Minnesota, USA.
authors: Mustafa A
authors: MA
authors: Arain
authors: Division of Gastroenterology, University of Minnesota, Minneapolis, Minnesota, USA.
authors: Shawn
authors: S
authors: Mallery
authors: Division of Gastroenterology, University of Minnesota, Minneapolis, Minnesota, USA.
authors: Martin L
authors: ML
authors: Freeman
mesh_terms: D003131:Combined Modality Therapy; D003952:Diagnostic Imaging; D016145:Endoscopy, Digestive System / Q000379:methods*; D006801:Humans; D019060:Minimally Invasive Surgical Procedures; D019283:Pancreatitis, Acute Necrotizing / Q000175:diagnosis / Q000628:therapy*; D016896:Treatment Outcome