title: Palladium-catalyzed formylation of aryl halides with tert-butyl isocyanide.
abstract: A novel palladium-catalyzed formylation of aryl halides with isocyanide in the presence of Et3SiH has been demonstrated, which provides a strategy toward important aldehydes with moderate to excellent yield. The advantage of this reaction includes milder conditions, convenient operation, lower toxicity, and wide functional group tolerance.
authors: College of Pharmaceutical Sciences, Soochow University , Suzhou, 215123, China.
authors: Xiao
authors: X
authors: Jiang
authors: Jin-Mei
authors: JM
authors: Wang
authors: Ying
authors: Y
authors: Zhang
authors: Zhong
authors: Z
authors: Chen
authors: Yong-Ming
authors: YM
authors: Zhu
authors: Shun-Jun
authors: SJ
authors: Ji
mesh_terms: D000447:Aldehydes / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D006847:Hydrocarbons, Iodinated / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D006842:Hydrocarbons, Brominated; D006847:Hydrocarbons, Iodinated; D009570:Nitriles; D010165:Palladium; C099535:tert-butyl isocyanide