title: Neoglycopeptide synthesis by suzuki-miyaura couplings between glycosyl aryl boronic acids and iodopeptides.
abstract: Suzuki-Miyaura coupling reaction was applied in the syntheses of neoglycopeptides. This work utilizes new type of glycosyl aryl boronic acid and readily accessible iodo amino acids/iodopeptides. Both carbohydrate and peptide moieties are unprotected and the final product could be isolated directly. The neoglyco amino acid and neoglycopeptide products feature an O-glycosyl biaryl linker between the carbohydrate and peptide moieties.
authors: Guohua
authors: G
authors: Chen
authors: Xiangying
authors: X
authors: Gu
authors: Lin
authors: L
authors: Chen
authors: Xin
authors: X
authors: Wang
authors: Yue-Lei
authors: YL
authors: Chen
authors: Jingkang
authors: J
authors: Shen
authors: School of Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, P.R. China. cgh63@163.com.
authors: Wenbin
authors: W
authors: Zeng
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D006020:Glycopeptides / Q000138:chemical synthesis*; D006031:Glycosylation; D007467:Iodoproteins / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry
chemical_list: D001897:Boronic Acids; D006020:Glycopeptides; D007467:Iodoproteins; D010165:Palladium