title: Crosstalk among Taenia crassiceps (ORF Strain) cysts regulates their rates of budding by ways of soluble and contact signals exchanged between them.
abstract: Herein we report that in vitro experiments with different initial parasite densities (1, 5, and 10 cysts per mL of culture medium) show that cysts at densities of 10 and 5 grow faster than those at 1, and that they release into the culture medium factors which increase the budding rates of the slower lower-density ones. Close contact among the incubated cysts also favors budding, thus suggesting the participation of surface sensors of parasite crowding. Thus, contact signals, together with the release of soluble growth factors, could endow cysts with the capacity to sense and regulate their numbers inside their habitat in relation to their population density.
authors: Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, A.P. 70228, 04510 México, DF, Mexico.
authors: Esquivel-Velázquez
authors: EV
authors: Marcela
authors: Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, A.P. 70228, 04510 México, DF, Mexico.
authors: Hernández
authors: H
authors: Ricardo
authors: Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, A.P. 70228, 04510 México, DF, Mexico.
authors: Larralde
authors: L
authors: Carlos
authors: Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, A.P. 70228, 04510 México, DF, Mexico.
authors: Ostoa-Saloma
authors: OS
authors: Pedro
mesh_terms: D000818:Animals; D002455:Cell Division; D003552:Cysticercus / Q000166:cytology; D005260:Female; D008807:Mice, Inbred BALB C; D010063:Ovum / Q000166:cytology*; D015398:Signal Transduction; D012995:Solubility; D013621:Taenia / Q000166:cytology* / Q000254:growth & development*