title: Effects of lipid-lowering agents on inflammation, haemostasis and blood pressure.
abstract: In addition to the modification of the lipid profile, most lipid-lowering agents appear to modulate other atherogenic pathways. We summarize the effects of lipid-lowering agents on inflammation, hemostasis and blood pressure. We also discuss the potential contribution of these actions on cardiovascular disease prevention. Most lipid-lowering agents appear to exert anti-inflammatory, antithrombotic and antihypertensive effects. These pleiotropic actions appear to contribute to the reduction in cardiovascular events and deep venous thrombosis during statin treatment. Regarding other lipid-lowering agents, it is unclear whether their effects on inflammation, thrombosis or blood pressure play a role in their antiatherogenic potential.
authors: Konstantinos
authors: K
authors: Tziomalos
authors: Asterios
authors: A
authors: Karagiannis
authors: Aristotle University, First Propedeutic Department of Internal Medicine, AHEPA Hospital, 1 Stilponos Kyriakidi street, 546 36, Thessaloniki, Greece. ktziomalos@yahoo.com.
authors: Vasilios G
authors: VG
authors: Athyros
mesh_terms: D001794:Blood Pressure / Q000187:drug effects*; D008078:Cholesterol, LDL / Q000097:blood; D006487:Hemostasis / Q000187:drug effects*; D006801:Humans; D000960:Hypolipidemic Agents / Q000494:pharmacology* / Q000627:therapeutic use*; D007249:Inflammation / Q000188:drug therapy*
chemical_list: D008078:Cholesterol, LDL; D000960:Hypolipidemic Agents