title: Health-related quality of life after kidney transplantation: who benefits the most?
abstract: The influence of dialysis modalities on HRQoL before and after kidney transplantation (KT) and the role of adherence to medication on HRQoL have not been fully studied. Sixty four dialysis patients who answered the 15D HRQoL survey during dialysis were surveyed again after KT. Adherence and employment were also investigated. The mean 15D score was highest among home hemodialysis patients (HHD) and lowest among in-center hemodialysis patients (icHD). After KT, the mean 15D score improved significantly in 78.6% of peritoneal dialysis patients (PD), 47.6% of HHD, and 53.8% of icHD. Then, mean 15D score remained unchanged in 28.6% of HHD and in 23.1% of icHD patients. A deterioration in the 15D score occurred in 14.3% of PD, 23.1% of icHD, and 23.8% of HHD patients, and this was influenced by the number of pills (P = 0.04). Adherence to medication was the lowest in PD, timing being the most challenging task showing a connection to higher creatinine concentration (never forgot 1.41 mg/dl vs. forgot 2.08 mg/dl P = 0.05). Employed patients had a higher mean 15D score. The icHD and PD patients benefited the most from KT and HHD the least. Low pill burden and employment were linked to a better HRQoL.
authors: Division of Nephrology, Department of Internal Medicine, Helsinki University Central Hospital, Helsinki, Finland.
authors: Fernanda
authors: F
authors: Ortiz
authors: Pasi
authors: P
authors: Aronen
authors: Petri K
authors: PK
authors: Koskinen
authors: Raija K
authors: RK
authors: Malmström
authors: Patrik
authors: P
authors: Finne
authors: Eero O
authors: EO
authors: Honkanen
authors: Harri
authors: H
authors: Sintonen
authors: Risto P
authors: RP
authors: Roine
mesh_terms: D000328:Adult; D000368:Aged; D003625:Data Collection; D004522:Educational Status; D004651:Employment; D005260:Female; D006437:Hemodialysis, Home; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery / Q000628:therapy; D016030:Kidney Transplantation; D008137:Longitudinal Studies; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D010530:Peritoneal Dialysis; D011788:Quality of Life; D006435:Renal Dialysis
keywords: adherence; dialysis; health-related quality of life; kidney transplantation