title: [Epidemiological analysis for enterococci isolated in Aichi prefecture].
abstract: We investigated vancomycin-resistant genes for clinical isolates of 353 vancomycin-resistant enterococci in the Aichi Medical University hospital and 120 vancomycin-resistant enterococci from the 8 facilities in Aichi prefecture between April 2008 and January 2013. We detected 8, 105, 21 and 4 strains of enterococci with vanA, vanB, vanC1 and vanC2/C3, respectively. Among enterococci with vancomycin-resistant genes, we detected 4, 3 and 2 enterococci of vancomycin MIC level 4 microg/mL with vanB, vanC1 and vanC2/C3, respectively. According to molecular analysis using repetitive-sequence-based PCR (rep-PCR) for enterococci with vanA or vanB genes, although there have been no similarity for Enterococcus faecium with vanA and Enterococcus faecalis with vanB, high similarity was shown among E. faecium with vanB, which might be nosocomial spread in each hospital. These results showed that molecular analysis for vancomycin-resistant genes would be useful for the management of healthcare-associated infections.
authors: Daisuke
authors: D
authors: Sakanashi
authors: Yuka
authors: Y
authors: Yamagishi
authors: Takayoshi
authors: T
authors: Suzuki
authors: Tomoko
authors: T
authors: Ohno
authors: Atsuko
authors: A
authors: Yamada
authors: Hiroyuki
authors: H
authors: Suematsu
authors: Hiroshige
authors: H
authors: Mikamo
mesh_terms: D016983:Enterococcus / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D020713:Vancomycin Resistance / Q000235:genetics*