title: Timing of surgery in rasmussen syndrome: is patience a virtue?
abstract: Rasmussen syndrome affects previously normal people and forever changes their lives and the lives of their families. Although understood as a probable autoimmune condition, medical treatment remains limited and surgery remains the only cure, although with inevitable functional consequences. Difficulties remain in deciding on the optimal timing of surgery. Here, we review data available to aid clinicians faced with making the decision of when to recommend hemispherectomy. Not all patients have rapidly progressive disease, however, and such patients may benefit from immunomodulatory treatment. Thus, a patient's clinical course requires careful evaluation in order to identify those who would benefit most from early surgery.
authors: Department of Neurology, Johns Hopkins Hospital, Baltimore, MD.
authors: Adam L
authors: AL
authors: Hartman
authors: Neurosciences Unit, UCL-Institute of Child Health, London, U.K.
authors: J Helen
authors: JH
authors: Cross