title: [Quantitative analysis of six flavonoids of hongzhu capsule by QAMS].
abstract: OBJECTIVE
  To establish a method of quality assurance for mass-screening (QAMS) for simultaneously determining six flavonoids in Hongzhu Capsules.
  
  
  METHODS
  An HPLC (high performance liquid chromatography) method was developed as QAMS to determine neoeriocitrin, prunin, naringin, rhoifolin, miliditin and naringenin in Hongzhu Capsules. Using naringin as the internal reference substance, relative correction factors (RCF) of the five flavonoids were determined and given as follows (1.05, 0.782, 1.89, 1.27, 0.532). The contents of the flavonoids in Hongzhu Capsules were determined by QAMS and validated by the external standard method.
  
  
  RESULTS
  RCF values were determined by HPLC with good reproducibility. No significant difference between the quantitative results of QAMS and external standard method was observed.
  
  
  CONCLUSIONS
  The present-developed method is convenient and accurate to determine multiple components when some standard substances are unavailable, thus considered as a potential method for quality control of Hongzhu Capsules.
authors: Wei
authors: W
authors: Peng
authors: Wei-wei
authors: WW
authors: Su
authors: Wei
authors: W
authors: Zou
authors: Fang-hui
authors: FH
authors: Zhu
authors: Jing
authors: J
authors: Guo
mesh_terms: D002214:Capsules; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004187:Disaccharides / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000592:standards; D044950:Flavanones / Q000737:chemistry; D005419:Flavonoids / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry; D010695:Phlorhizin / Q000031:analogs & derivatives / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011786:Quality Control; D015203:Reproducibility of Results; D005947:Glucose / Q000031:analogs & derivatives; D008358:Mannose / Q000031:analogs & derivatives; D047310:Apigenin
chemical_list: D002214:Capsules; D004187:Disaccharides; D004365:Drugs, Chinese Herbal; D044950:Flavanones; D005419:Flavonoids; D006027:Glycosides; D010695:Phlorhizin; C553460:neoeriocitrin; C506622:prunin; C005273:naringenin; C089378:rhoifolin; D005947:Glucose; D008358:Mannose; D047310:Apigenin; C005274:naringin