title: Delirium during Weaning from Mechanical Ventilation.
abstract: Background. We compare the incidence of delirium before and after extubation and identify the risk factors and possible predictors for the occurrence of delirium in this group of patients. Methods. Patients weaned from mechanical ventilation (MV) and extubated were included. The assessment of delirium was conducted using the confusion assessment method for the ICU and completed twice per day until discharge from the intensive care unit. Results. Sixty-four patients were included in the study, 53.1% of whom presented with delirium. The risk factors of delirium were age (P = 0.01), SOFA score (P = 0.03), APACHE score (P = 0.01), and a neurological cause of admission (P = 0.01). The majority of the patients began with delirium before or on the day of extubation. Hypoactive delirium was the most common form. Conclusion. Acute (traumatic or medical) neurological injuries were important risk factors in the development of delirium. During the weaning process, delirium developed predominantly before or on the same day of extubation and was generally hypoactive (more difficult to detect). Therefore, while planning early prevention strategies, attention must be focused on neurological patients who are receiving MV and possibly even on patients who are still under sedation.
authors: Intensive Care Unit, Western Parana State University Hospital, Avenue Tancredo Neves 3224, Santo Onofre, 85806-470 Cascavel, PR, Brazil.
authors: Marcela Aparecida
authors: 0000-0001-8953-2799
authors: MA
authors: Leite
authors: Intensive Care Unit, Western Parana State University Hospital, Avenue Tancredo Neves 3224, Santo Onofre, 85806-470 Cascavel, PR, Brazil.
authors: Erica Fernanda
authors: EF
authors: Osaku
authors: Intensive Care Unit, Western Parana State University Hospital, Avenue Tancredo Neves 3224, Santo Onofre, 85806-470 Cascavel, PR, Brazil.
authors: Claudia Rejane Lima de Macedo
authors: CR
authors: Costa
authors: Intensive Care Unit, Western Parana State University Hospital, Avenue Tancredo Neves 3224, Santo Onofre, 85806-470 Cascavel, PR, Brazil.
authors: Maria Fernanda
authors: MF
authors: Cândia
authors: Intensive Care Unit, Western Parana State University Hospital, Avenue Tancredo Neves 3224, Santo Onofre, 85806-470 Cascavel, PR, Brazil.
authors: Beatriz
authors: B
authors: Toccolini
authors: Intensive Care Unit, Western Parana State University Hospital, Avenue Tancredo Neves 3224, Santo Onofre, 85806-470 Cascavel, PR, Brazil.
authors: Caroline
authors: C
authors: Covatti
authors: Intensive Care Unit, Western Parana State University Hospital, Avenue Tancredo Neves 3224, Santo Onofre, 85806-470 Cascavel, PR, Brazil.
authors: Nicolle Lamberti
authors: NL
authors: Costa
authors: Intensive Care Unit, Western Parana State University Hospital, Avenue Tancredo Neves 3224, Santo Onofre, 85806-470 Cascavel, PR, Brazil.
authors: Sandy Teixeira
authors: ST
authors: Nogueira
authors: Intensive Care Unit, Western Parana State University Hospital, Avenue Tancredo Neves 3224, Santo Onofre, 85806-470 Cascavel, PR, Brazil.
authors: Suely Mariko
authors: SM
authors: Ogasawara
authors: Intensive Care Unit, Western Parana State University Hospital, Avenue Tancredo Neves 3224, Santo Onofre, 85806-470 Cascavel, PR, Brazil.
authors: Carlos Eduardo
authors: CE
authors: de Albuquerque
authors: Intensive Care Unit, Western Parana State University Hospital, Avenue Tancredo Neves 3224, Santo Onofre, 85806-470 Cascavel, PR, Brazil.
authors: Cleverson Marcelo
authors: 0000-0002-8930-9113
authors: CM
authors: Pilatti
authors: Western Parana State University, Rua da Faculdade 645, Jardim La Salle, 85903-000 Toledo, PR, Brazil.
authors: Pitágoras Augusto
authors: PA
authors: Piana
authors: Intensive Care Unit, Western Parana State University Hospital, Avenue Tancredo Neves 3224, Santo Onofre, 85806-470 Cascavel, PR, Brazil.
authors: Amaury Cezar
authors: AC
authors: Jorge
authors: Intensive Care Unit, Western Parana State University Hospital, Avenue Tancredo Neves 3224, Santo Onofre, 85806-470 Cascavel, PR, Brazil ; Western Parana State University Hospital, Department of Medicine, Avenue Tancredo Neves 3224, Santo Onofre, 85806-470 Cascavel, PR, Brazil.
authors: Péricles Almeida Delfino
authors: PA
authors: Duarte