title: Is 18F-flutemetamol PET/CT able to reveal cardiac amyloidosis?
abstract: We report here the case of a 56-year-old man with well-documented cardiac light chain amyloidosis successfully imaged with F-flutemetamol PET/CT in 2011. A matched pair healthy volunteer was imaged in the same conditions, and no specific heart uptake could be detected. The present report suggests the potential benefit of this new pharmaceutical in this indication, as it has been recently reported for C-Pittsburgh compound B, but with the main advantage to benefit from the more practical half-life of F. Further prospective trials would, however, be required to define the potential impact of F-flutemetamol PET/CT in cardiac amyloidosis.
authors: From the Departments of *Nuclear Medicine, †Pathology, ‡Neurology, §Hematology, and ¶Cardiology, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, Brussels, Belgium.
authors: Renaud
authors: R
authors: Lhommel
authors: Christine
authors: C
authors: Sempoux
authors: Adrian
authors: A
authors: Ivanoiu
authors: Lucienne
authors: L
authors: Michaux
authors: Bernhard
authors: B
authors: Gerber
mesh_terms: D000686:Amyloidosis / Q000000981:diagnostic imaging*; D000814:Aniline Compounds; D052160:Benzothiazoles; D009202:Cardiomyopathies / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D013844:Thiazoles; D014057:Tomography, X-Ray Computed
chemical_list: C475519:2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole; D000814:Aniline Compounds; D052160:Benzothiazoles; D019275:Radiopharmaceuticals; D013844:Thiazoles; C581552:flutemetamol