title: Securinega alkaloids from the fruits of Flueggea suffruticosa.
abstract: Phytochemical investigation on the fruits of Flueggea suffruticosa resulted in the isolation of three new Securinega alkaloids, secu'amamine H (1), 15β-methoxy-14,15-dihydrosecurinine (3), and securinol E (7), as well as eight known ones (2, 4-6, and 8-11). Their structures were elucidated by means of spectroscopic techniques (1D and 2D NMR, MS, UV, and IR). The absolute configurations of the new compounds were established by single-crystal X-ray diffraction and CD analyses.
authors: a Department of Natural Medicinal Chemistry , China Pharmaceutical University , Nanjing 210009 , China.
authors: Li
authors: L
authors: Zhou
authors: Bing-Xin
authors: BX
authors: Zhao
authors: Ren-Wang
authors: RW
authors: Jiang
authors: Xiao-Jun
authors: XJ
authors: Huang
authors: Zhen-Long
authors: ZL
authors: Wu
authors: Ying
authors: Y
authors: Wang
authors: Wen-Cai
authors: WC
authors: Ye
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D018360:Crystallography, X-Ray; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D019665:Euphorbiaceae / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: D000470:Alkaloids; D004365:Drugs, Chinese Herbal
keywords: Euphorbiaceae; Flueggea suffruticosa; Securinega alkaloids