title: Homogeneous Pd-catalyzed transformation of terminal alkenes into primary allylic alcohols and derivatives.
abstract: Synthesis of primary alcohols from terminal alkenes is an important process in both bulk and fine chemical syntheses. Herein, a homogeneous Pd-complex-catalyzed transformation of terminal alkenes into primary allylic alcohols, by using 5 mol % [Pd(PPh3)4] as a catalyst, and H2O, CO2, and quinone derivatives as reagents, is reported. When alcohols were used instead of H2O, allylic ethers were obtained. A proposed mechanism includes the addition of oxygen nucleophiles at the less-hindered terminal position of π-allyl Pd intermediates.
authors: Department of Chemistry, Kyushu University, Fukuoka 812-8581 and Japan Science & Technology Agency (JST), ALCA (Japan), Fax: (+81) 92-642-7528.
authors: Ren
authors: R
authors: Tomita
authors: Kohei
authors: K
authors: Mantani
authors: Akiyuki
authors: A
authors: Hamasaki
authors: Tamao
authors: T
authors: Ishida
authors: Makoto
authors: M
authors: Tokunaga
keywords: homogeneous catalysis; palladium; primary allylic alcohols; terminal alkenes