title: Acute lymphocytic leukemia with superimposed invasive aspergillosis and pneumopericardium successfully treated with voriconazole.
abstract: We present a 47-year-old man with acute lymphocytic leukemia with a pericardial friction rub heralding pericardial aspergillosis. The clinical course was complicated by pneumopericardium, likely secondary to a direct connection between the lung parenchyma and the pericardial space. Bronchoalveolar lavage cultures returned positive for methicillin-resistant Staphylococcus aureus and Aspergillus niger. Combination voriconazole and vancomycin resulted in symptomatic improvement within 2 weeks of hospitalization.
authors: Division of Cardiology, New York University Langone Medical Center, New York, NY (Alviar); Lennox Hill Hospital, New York, NY (Doherty); and Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Vaduganathan).
authors: Carlos L
authors: CL
authors: Alviar
authors: Division of Cardiology, New York University Langone Medical Center, New York, NY (Alviar); Lennox Hill Hospital, New York, NY (Doherty); and Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Vaduganathan).
authors: Bryan
authors: B
authors: Doherty
authors: Division of Cardiology, New York University Langone Medical Center, New York, NY (Alviar); Lennox Hill Hospital, New York, NY (Doherty); and Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Vaduganathan).
authors: Muthiah
authors: M
authors: Vaduganathan