title: MR-guided focused ultrasound: a new generation treatment of Parkinson's disease, essential tremor and neuropathic pain.
abstract: The application of high intense focused ultrasound (HIFU) is currently the subject of many experimental and clinical trials. The combination of HIFU with MRI guidance known as MR-guided focused ultrasound (MRgFUS) appears to be particularly promising to ablate tissues located deep in the brain. The method can be the beginning of interventional neurology and an important alternative to neurosurgery. Studies conducted to date show the effectiveness of the method both in chronic diseases and in emergency cases. The safety and effectiveness of this method have been observed in parkinsonian and essential tremor as well as in neuropathic pain. The procedure does not require anaesthesia. Ionizing radiation is not used and there is no risk of cumulative dose. Such advantages may result in low complication rates and medical justification for further development of MRgFUS.
authors: Clinical Department of Neurology, Medical University of Silesia; Zabrze, Poland - paweldobrakowski@interia.pl.
authors: Pawel Piotr
authors: PP
authors: Dobrakowski
authors: Clinical Department of Neurology, Medical University of Silesia; Zabrze, Poland.
authors: Agnieszka Kamila
authors: AK
authors: Machowska-Majchrzak
authors: Clinical Department of Neurology, Medical University of Silesia; Zabrze, Poland.
authors: Beata
authors: B
authors: Labuz-Roszak
authors: Clinical Department of Neurology, Medical University of Silesia; Zabrze, Poland.
authors: Krzysztof Grzegorz
authors: KG
authors: Majchrzak
authors: Clinical Department of Neurology, Medical University of Silesia; Zabrze, Poland.
authors: Ewa
authors: E
authors: Kluczewska
authors: Clinical Department of Neurology, Medical University of Silesia; Zabrze, Poland.
authors: Krystyna Barbara
authors: KB
authors: Pierzchała
mesh_terms: D020329:Essential Tremor / Q000175:diagnosis / Q000628:therapy*; D019317:Evidence-Based Medicine; D057086:High-Intensity Focused Ultrasound Ablation / Q000379:methods*; D006801:Humans; D053783:Magnetic Resonance Imaging, Interventional / Q000379:methods*; D009437:Neuralgia / Q000175:diagnosis / Q000628:therapy*; D010300:Parkinson Disease / Q000175:diagnosis / Q000628:therapy*; D016896:Treatment Outcome
keywords: MR-guided focused ultrasound; essential tremor; neuropathic pain; parkinsonian tremor