title: Dynamics of changes in physiological parameters of mice with different radiosensitivity after acute γ-irradiation.
abstract: We studied radiosensitivity of 101/Hf, C3H/Sn, and C57Bl mice exposed to sublethal doses of γ-radiation. C57Bl mice responded to radiation much later than 101/Hf and C3H/Sn mice, while their adaptability was high enough. 101/Hf and C3H/Sn mice developed acute radiation sickness in a similar way. However, C3H/Sn mice showed better physiological indicators after radiation crisis. There was no noticeable improvement after the development of radiation sickness in 101/Hf mice. To assess individual radiosensitivity, integrated approach should be applied using the data obtained by different methods on several physiological levels.
authors: Research Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia, labpolys@gmail.com.
authors: I B
authors: IB
authors: Alchinova
authors: E N
authors: EN
authors: Arkhipova
authors: Yu S
authors: YS
authors: Medvedeva
authors: A B
authors: AB
authors: Cherepov
authors: M Yu
authors: MY
authors: Karganov
mesh_terms: D000818:Animals; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D051379:Mice; D008810:Mice, Inbred C57BL; D011833:Radiation Injuries, Experimental; D011836:Radiation Tolerance