title: Soft tissue giant cell tumor of low malignant potential of mediastinum: a rare case report.
abstract: Giant cell tumor (GCT) is primarily a bone neoplasm. Rare origin of the tumor from soft tissues has been reported. Involvement of mediastinum by GCT is even rarer. We herein describe an interesting case of huge mediastinal tumor in a young man. Radiologically, no primary osseous lesion was present throughout the body. Morphologically, tumor resembles osseous GCT with increased mitotic activity. Hence, the case was diagnosed as soft tissue GCT of low malignant potential at the rare site of mediastinum. To the best of our knowledge, the present case is the fourth reported case. Pathologists and clinicians need to be aware of the rare diagnosis of GCT in mediastinum and should carefully evaluate the clinical and radiological findings.
authors: All India Institute of Medical Sciences, New Delhi, India deepalijain76@gmail.com.
authors: Deepali
authors: D
authors: Jain
authors: All India Institute of Medical Sciences, New Delhi, India.
authors: Sudheer
authors: S
authors: Arava
authors: All India Institute of Medical Sciences, New Delhi, India.
authors: Biplab
authors: B
authors: Mishra
authors: All India Institute of Medical Sciences, New Delhi, India.
authors: Sanjay
authors: S
authors: Sharma
authors: All India Institute of Medical Sciences, New Delhi, India.
authors: Raju
authors: R
authors: Sharma
authors: All India Institute of Medical Sciences, New Delhi, India.
authors: Rajinder
authors: R
authors: Parshad
mesh_terms: D000328:Adult; D005870:Giant Cell Tumors / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000473:pathology* / Q000601:surgery
keywords: GCT; giant cell tumor; mediastinum; soft tissue