title: Cysteine-cystine redox cycling in a gold-gold dual-plate generator-collector microtrench sensor.
abstract: Thiols and disulfides are ubiquitous and important analytical targets. However, their redox properties, in particular on gold sensor electrodes, are complex and obscured by strong adsorption. Here, a gold-gold dual-plate microtrench dual-electrode sensor with feedback signal amplification is demonstrated to give well-defined (but kinetically limited) steady-state voltammetric current responses for the cysteine-cystine redox cycle in nondegassed aqueous buffer media at pH 7 down to micromolar concentration levels.
authors: Department of Electronic & Electrical Engineering, University of Bath , Bath BA2 7AY, U.K.
authors: Jules L
authors: JL
authors: Hammond
authors: Andrew J
authors: AJ
authors: Gross
authors: Pedro
authors: P
authors: Estrela
authors: Jesus
authors: J
authors: Iniesta
authors: Stephen J
authors: SJ
authors: Green
authors: C Peter
authors: CP
authors: Winlove
authors: Paul G
authors: PG
authors: Winyard
authors: Nigel
authors: N
authors: Benjamin
authors: Frank
authors: F
authors: Marken
mesh_terms: D003545:Cysteine / Q000032:analysis* / Q000737:chemistry*; D003553:Cystine / Q000032:analysis* / Q000737:chemistry; D055664:Electrochemical Techniques / Q000295:instrumentation* / Q000379:methods*; D004566:Electrodes; D004867:Equipment Design; D006046:Gold; D010084:Oxidation-Reduction
chemical_list: D003553:Cystine; D006046:Gold; D003545:Cysteine