title: Bifidobacterium animalis ssp. lactis BI07 modulates the tumor necrosis factor alpha-dependent imbalances of the enterocyte-associated intestinal microbiota fraction.
abstract: Using a previously developed in vitro model to characterize the enterocyte-adherent microbiota fraction, we explored the potential of the probiotic strain Bifidobacterium animalis ssp. lactis BI07 to modulate the inflammation-dependent dysbioses of the enterocyte-adherent microbiota from 12 healthy human donors. According to our findings, B. animalis ssp. lactis BI07 is effective in limiting the increase of pro-inflammatory pathobionts on the inflamed mucosal site, supporting the recovery of a mutualistic community.
authors: Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
authors: Manuela
authors: M
authors: Centanni
authors: Silvia
authors: S
authors: Turroni
authors: Simone
authors: S
authors: Rampelli
authors: Elena
authors: E
authors: Biagi
authors: Sara
authors: S
authors: Quercia
authors: Clarissa
authors: C
authors: Consolandi
authors: Marco
authors: M
authors: Severgnini
authors: Patrizia
authors: P
authors: Brigidi
authors: Marco
authors: M
authors: Candela
mesh_terms: D000328:Adult; D001644:Bifidobacterium / Q000276:immunology*; D064806:Dysbiosis / Q000276:immunology; D020895:Enterocytes / Q000276:immunology* / Q000382:microbiology*; D041981:Gastrointestinal Tract / Q000276:immunology* / Q000382:microbiology*; D006801:Humans; D014409:Tumor Necrosis Factor-alpha / Q000276:immunology*; D055815:Young Adult
chemical_list: C439524:TNF protein, human; D014409:Tumor Necrosis Factor-alpha
keywords: Bifidobacterium lactis; gut inflammation; gut microbiota; probiotics