title: Synthesis of water-compatible surface-imprinted polymer via click chemistry and RAFT precipitation polymerization for highly selective and sensitive electrochemical assay of fenitrothion.
abstract: A novel water-compatible fenitrothion imprinted polymer was prepared on Au nanoparticles (AuNPs) by click chemistry and reversible addition-fragmentation chain transfer (RAFT) precipitation polymerization (RAFTPP). The RAFT chain-transfer agent was synthesized on the surface of AuNPs using click chemistry, then an imprinted polymer with hydrophilic polymer brushes was prepared on the RAFT chain-transfer agent modified AuNPs by RAFTPP, mediated by hydrophilic polyethylene glycol macromolecular cochain-transfer agent. The obtained molecularly imprinted material showed improved accessibility to fenitrothion and recognition property in water medium. When the material was immobilized on an ionic liquid functionalized graphene coated glassy carbon electrode for the electrochemical determination of fenitrothion, the resulting electrochemical sensor presented linear response in the range of 0.01-5 μM, with a sensitivity of 6.1 μA/μM mm(2). The low limit of detection was 8 nM (S/N=3). The sensor was successfully applied to the determination of real samples and the recovery for standard added was 95-108%.
authors: Key Laboratory of Analytical Chemistry for Biology and Medicine, (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, Hubei Province, PR China.
authors: Lijuan
authors: L
authors: Zhao
authors: Key Laboratory of Analytical Chemistry for Biology and Medicine, (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, Hubei Province, PR China.
authors: Faqiong
authors: F
authors: Zhao
authors: Key Laboratory of Analytical Chemistry for Biology and Medicine, (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, Hubei Province, PR China. Electronic address: bzzeng@whu.edu.cn.
authors: Baizhao
authors: B
authors: Zeng
mesh_terms: D011232:Chemical Precipitation; D002800:Cholinesterase Inhibitors / Q000032:analysis*; D057930:Click Chemistry / Q000379:methods; D055664:Electrochemical Techniques / Q000379:methods*; D005278:Fenitrothion / Q000032:analysis*; D006046:Gold / Q000737:chemistry; D006108:Graphite / Q000737:chemistry; D007306:Insecticides / Q000032:analysis*; D057230:Limit of Detection; D053768:Metal Nanoparticles / Q000737:chemistry / Q000648:ultrastructure; D054802:Molecular Imprinting / Q000379:methods*; D058105:Polymerization; D011108:Polymers / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D002800:Cholinesterase Inhibitors; D007306:Insecticides; D011108:Polymers; D014867:Water; D006046:Gold; D006108:Graphite; D005278:Fenitrothion
keywords: Au nanoparticles; Electrochemical sensor; Fenitrothion; Graphene; Molecularly imprinted polymer