title: Physical activity and health-related quality of life: US adults with and without limitations.
abstract: OBJECTIVE
  The purpose of this study was to examine the dose-response relationship between physical activity (PA) and health-related quality of life (HRQOL) among adults with and without limitations.
  
  
  METHODS
  We dichotomized HRQOL as ≥14 unhealthy (physical or mental) days (past 30 days), or <14 unhealthy days. By using a moderate-intensity minute equivalent, PA categories were as follows: inactive, 10-60, 61-149, 150-300, and >300 min/week. Persons with limitations reported having problems that limited their activities or required use of special equipment. Age-adjusted prevalence estimates and logistic regression analyses were performed with 2009 Behavioral Risk Factor Surveillance System data (n = 357,665), controlling for demographics, BMI, smoking, and heavy alcohol use.
  
  
  RESULTS
  For adults without limitations, the odds of ≥14 unhealthy days were lower among adults obtaining any PA (10-60 min/week, AOR = 0.79, 95 % CI 0.70, 0.88), compared with those inactive. A quadratic trend (P < 0.001) indicated enhanced HRQOL with each PA level, but improvements were less marked between lower and upper sufficient PA categories (150-300 and >300 min/week). Because of a significant age interaction, persons with limitations were stratified by age (18-34, 35-64, and 65+ years). Findings for persons aged 35 years or older with limitations were similar to those without limitations. Lower odds of poor HRQOL for persons aged 18-34 years with limitations were associated with recommended levels of PA (150-300 min/week; AOR = 0.61, 95 % CI 0.43, 0.88 and >300 min/week; AOR = 0.58, 95 % CI 0.43, 0.80).
  
  
  CONCLUSIONS
  PA is positively associated with HRQOL among persons with and without limitations.
authors: Division of Nutrition, Physical Activity and Obesity, Centers for Disease Control and Prevention, MS K-77, 4770 Buford Hwy, N.E., Atlanta, GA, 30341-3724, USA, drb8@cdc.gov.
authors: David R
authors: DR
authors: Brown
authors: Dianna D
authors: DD
authors: Carroll
authors: Lauren M
authors: LM
authors: Workman
authors: Susan A
authors: SA
authors: Carlson
authors: David W
authors: DW
authors: Brown
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D040343:Behavioral Risk Factor Surveillance System; D006233:Persons with Disabilities / Q000523:psychology*; D015444:Exercise / Q000502:physiology* / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011788:Quality of Life / Q000523:psychology*; D012907:Smoking; D011795:Surveys and Questionnaires; D014481:United States; D055815:Young Adult