title: Optical coherence tomography for the evaluation of asymmetric cardiac allograft vasculopathy in a child.
abstract: We present an unusual case of CAV in a child with isolated disease in the LAD coronary artery. Initial progression of the disease appeared to have been halted by the use of sirolimus, but the assessment of disease in other vessels (particularly the RCA) was of particular importance in deciding whether or not to relist this patient for transplantation. Due to the known limitations of coronary angiography, we used OCT to assess for angiographically silent CAV. The normal intravascular appearance of the RCA by OCT was reassuring, and the child was not relisted for transplantation. OCT offers multiple advantages for the assessment of CAV in children.
authors: Section of Cardiology and Department of Pediatrics, Alberta Children's Hospital, Calgary, AB, Canada.
authors: Steven C
authors: SC
authors: Greenway
authors: Martin
authors: M
authors: Hosking
authors: Kevin C
authors: KC
authors: Harris
mesh_terms: D064591:Allografts; D002648:Child; D003324:Coronary Artery Disease / Q000175:diagnosis* / Q000209:etiology*; D003331:Coronary Vessels; D018450:Disease Progression; D005260:Female; D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome / Q000601:surgery; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D020123:Sirolimus / Q000627:therapeutic use; D041623:Tomography, Optical Coherence
chemical_list: D007166:Immunosuppressive Agents; D020123:Sirolimus
keywords: heart transplant; optical coherence tomography; pediatric; vasculopathy