title: Capture and identification of the volatile components in crude and processed herbal medicines through on-line purge and trap technique coupled with GC × GC-TOF MS.
abstract: This work aimed to investigate the volatile components in crude and processed herbal medicines (HMs). Using Atractylodis Macrocephalae Rhizoma (AMR) as a model HM, the volatile components were captured through on-line purge and trap technique and identified by using comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry (GC × GC-TOF MS) system. A total of 224 and 171 volatile compounds were identified in crude and processed AMR samples, respectively. After frying with honey-bran, 52 compounds which were found in crude AMR samples disappeared in processed AMR samples, and 15 compounds were newly generated in processed AMR. The established method can be applied in different research areas such as HM and food processing.
authors: a Research Center of TCM Processing Technology, Zhejiang Chinese Medical University , Hangzhou , P.R. China.
authors: Gang
authors: G
authors: Cao
authors: Zhiwei
authors: Z
authors: Xu
authors: Xin
authors: X
authors: Wu
authors: Qingli
authors: Q
authors: Li
authors: Xiaocheng
authors: X
authors: Chen
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D029001:Herbal Medicine; D009822:Oils, Volatile / Q000032:analysis*; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry
chemical_list: D004365:Drugs, Chinese Herbal; D009822:Oils, Volatile
keywords: Atractylodis Macrocephalae Rhizoma; herbal medicines; on-line purge and trap; two-dimensional gas chromatography–time-of-flight mass spectrometry; volatile components