title: Unusual biliary myoepithelial carcinoma in liver-case report and immunohistochemical study.
abstract: Myoepithelial carcinoma is a well-known tumor of salivary gland, representing 1% of all salivary gland tumors. They have also been reported in other sites as skin/soft tissue, breast and lung. This paper reports a rare case of primary myoepithelial carcinoma in the liver, as well as discusses the findings of immunohistochemistry. The clinical manifestations, imaging characteristics, and histopathological changes of myoepithelial carcinoma in this case were described. The patient was a 33 years old female presented with a cystic tumor in the right lobe of the liver. As the liver tumor increased in size within six months, malignant neoplasm was suspected and thus anterior hepatic segmentectomy was performed. The mass composed of glandular-like structures and trabecular sheets of spindled shaped cells and epithelioid cells which were positive for myoepithelial markers. The tumor recurred within one year, in the left lobe of the liver and partial left lobe lobectomy was performed. The tumor resected showed similar histology to the primary tumor. Three months later, another recurrence was noted for which radiofrequency ablation was performed. This report presents a recurrent case of myoepithelial carcinoma in the liver and suggests the possibility of biliary origin of such tumor.
authors: Department of Pathology and Experimental Medicine, Kumamoto University, Graduate School of Medical Sciences Kumamoto, Japan ; Department of Pathology, Faculty of Medicine, Suez Canal University Ismailia, Egypt.
authors: Wael
authors: W
authors: Hassan
authors: Department of Radiology, Kumamoto Shinto General Hospital Kumamoto, Japan.
authors: Junko
authors: J
authors: Nishi
authors: Department of Surgery, Kumamoto Shinto General Hospital Kumamoto, Japan.
authors: Shinjiro
authors: S
authors: Tomiyasu
authors: Department of Radiology, Kumamoto Shinto General Hospital Kumamoto, Japan.
authors: Tadahito
authors: T
authors: Urakado
authors: Department of Gastroenterology and Hepatology, Kumamoto Shinto General Hospital Kumamoto, Japan.
authors: Katsuki
authors: K
authors: Haraoka
authors: Department of Surgery, Kumamoto Shinto General Hospital Kumamoto, Japan.
authors: Tuyoshi
authors: T
authors: Yamanaka
authors: Department of Gastroenterology and Hepatology, Kumamoto Shinto General Hospital Kumamoto, Japan.
authors: Shigetoshi
authors: S
authors: Fujiyama
authors: Department of Pathology and Experimental Medicine, Kumamoto University, Graduate School of Medical Sciences Kumamoto, Japan.
authors: Takaaki
authors: T
authors: Ito
mesh_terms: D000328:Adult; D001650:Bile Duct Neoplasms / Q000737:chemistry* / Q000473:pathology / Q000601:surgery; D001653:Bile Ducts, Intrahepatic / Q000737:chemistry* / Q000473:pathology / Q000601:surgery; D014408:Biomarkers, Tumor / Q000032:analysis*; D001706:Biopsy; D017115:Catheter Ablation; D005260:Female; D006498:Hepatectomy; D006801:Humans; D007150:Immunohistochemistry; D009208:Myoepithelioma / Q000737:chemistry* / Q000473:pathology / Q000601:surgery; D009364:Neoplasm Recurrence, Local; D018297:Neoplasms, Cystic, Mucinous, and Serous / Q000737:chemistry* / Q000473:pathology / Q000601:surgery; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D012086:Reoperation; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor
keywords: Recurrent myoepithelial carcinoma; immunohistochemistry; liver