title: Sterols and Terpenoids from Viburnum odoratissimum.
abstract: A new stigmasterol type natural product, viburodorol A (1), along with eleven known sterols and terpenoids (2-12), were isolated from the aerial parts of Viburnum odoratissimum. The structure of 1 was elucidated on the basis of comprehensive spectroscopic analysis. It's noteworthy that compound 2, the major constituent of this plant, can significantly stimulate glucose absorption in insulin resistant HepG2 cells without affecting cell viability. Furthermore, this compound can also restore the glucose absorption in DXMS-induced insulin resistant 3T3-L1 cells.
authors: Southwest Forestry University, Kunming, 650224 People's Republic of China ; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 People's Republic of China.
authors: Jun-Zeng
authors: JZ
authors: Ma
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 People's Republic of China.
authors: Xing-Wei
authors: XW
authors: Yang
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 People's Republic of China.
authors: Jing-Jing
authors: JJ
authors: Zhang
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 People's Republic of China.
authors: Xia
authors: X
authors: Liu
authors: Southwest Forestry University, Kunming, 650224 People's Republic of China.
authors: Li-Lan
authors: LL
authors: Deng
authors: Laboratory of Chinese Herbal Drug Discovery, Tropical Medicine Institute, Guangzhou University of Chinese Medicine, Guangzhou, 510405 People's Republic of China.
authors: Xiao-Ling
authors: XL
authors: Shen
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 People's Republic of China.
authors: Gang
authors: G
authors: Xu
keywords: 6α-Hydroxy-lup-20(29)-en-3-on-28-oic acid; Insulin sensitizing activity; Viburnum odoratissimum; Viburodorol A