title: Bioactivities of Compounds from Elephantopus scaber, an Ethnomedicinal Plant from Southwest China.
abstract: Elephantopus scaber is an ethnomedicinal plant used by the Zhuang people in Southwest China to treat headaches, colds, diarrhea, hepatitis, and bronchitis. A new δ -truxinate derivative, ethyl, methyl 3,4,3',4'-tetrahydroxy- δ -truxinate (1), was isolated from the ethyl acetate extract of the entire plant, along with 4 known compounds. The antioxidant activity of these 5 compounds was determined by ABTS radical scavenging assay. Compound 1 was also tested for its cytotoxicity effect against HepG2 by MTT assay (IC50 = 60  μ M), and its potential anti-inflammatory, antibiotic, and antitumor bioactivities were predicted using target fishing method software.
authors: College of Life and Environmental Sciences, Minzu University of China, 27 Zhong-Guan-Cun South Avenue, Haidian District, Beijing 100081, China.
authors: Jianjun
authors: J
authors: Wang
authors: College of Life and Environmental Sciences, Minzu University of China, 27 Zhong-Guan-Cun South Avenue, Haidian District, Beijing 100081, China.
authors: Ping
authors: P
authors: Li
authors: School of Chinese Materia Medica, Beijing University of Chinese Medicine, 11 Third Ring Road, Chaoyang District, Beijing 100029, China.
authors: Baosai
authors: B
authors: Li
authors: College of Life and Environmental Sciences, Minzu University of China, 27 Zhong-Guan-Cun South Avenue, Haidian District, Beijing 100081, China.
authors: Zhiyong
authors: Z
authors: Guo
authors: College of Life and Environmental Sciences, Minzu University of China, 27 Zhong-Guan-Cun South Avenue, Haidian District, Beijing 100081, China ; Department of Biological Science, Lehman College, and Graduate Center, City University of New York, 250 Bedford Park Boulevard West, Bronx, NY 10468, USA.
authors: Edward J
authors: EJ
authors: Kennelly
authors: College of Life and Environmental Sciences, Minzu University of China, 27 Zhong-Guan-Cun South Avenue, Haidian District, Beijing 100081, China ; Kunming Institute of Botany, Chinese Academy of Sciences, 132 Lanhei Road, Kunming 650201, China.
authors: Chunlin
authors: C
authors: Long