title: Elastosis perforans serpiginosa: a case successfully treated with intralesional steroids and topical allium cepa-allantoin-pentaglycan gel.
abstract: Elastosis perforans serpiginosa is a rare skin disease in which abnormal elastic fibers, other connective tissue elements, and cellular debris are expelled from the papillary dermis through the epidermis. Three clinical variants of EPS can be detected: idiopathic, reactive, and drug-induced. Clinically it consists of small horny or umbilicated papules arranged in a linear, arciform, circular, or serpiginous pattern. It usually occurs in young adults and shows a predilection for the head and neck. The lesions are generally asymptomatic or slightly itching. Several treatments have been reported with poor long-term success; these include intralesional and topical corticosteroids, tazarotene, imiquimod, and cryotherapy. We report a case of 40-year-old black woman affected by elastosis perforans serpiginosa that was referred to our department and treated with intralesional injections of triamcinolone acetonide and topical application of allium cepa-allantoin-pentaglycan gel.
authors: Dermatological Clinic, Department of Clinical and Molecular Medicine, Marche Polytechnic University, Ancona, Italy.
authors: Anna
authors: A
authors: Campanati
authors: Dermatological Clinic, Department of Clinical and Molecular Medicine, Marche Polytechnic University, Ancona, Italy.
authors: Emanuela
authors: E
authors: Martina
authors: Dermatological Clinic, Department of Clinical and Molecular Medicine, Marche Polytechnic University, Ancona, Italy. Corresponding author: katiagiuliodori79@yahoo.it.
authors: Katia
authors: K
authors: Giuliodori
authors: Dermatological Clinic, Department of Clinical and Molecular Medicine, Marche Polytechnic University, Ancona, Italy.
authors: Giulia
authors: G
authors: Ganzetti
authors: Dermatological Clinic, Department of Clinical and Molecular Medicine, Marche Polytechnic University, Ancona, Italy.
authors: Barbara
authors: B
authors: Marconi
authors: Dermatological Clinic, Department of Clinical and Molecular Medicine, Marche Polytechnic University, Ancona, Italy.
authors: Irene
authors: I
authors: Conta
authors: Department of Neurosciences, Institute of Anatomic Pathology, Marche Polytechnic University, Ancona, Italy.
authors: Mirella
authors: M
authors: Giangiacomi
authors: Dermatological Clinic, Department of Clinical and Molecular Medicine, Marche Polytechnic University, Ancona, Italy.
authors: Annamaria
authors: A
authors: Offidani
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000481:Allantoin / Q000008:administration & dosage*; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D015552:Injections, Intralesional; D019697:Onions; D010936:Plant Extracts / Q000008:administration & dosage*; D011134:Polysaccharides / Q000008:administration & dosage*; D012074:Remission Induction; D012871:Skin Diseases / Q000188:drug therapy*; D014222:Triamcinolone Acetonide / Q000008:administration & dosage*
chemical_list: D005938:Glucocorticoids; D010936:Plant Extracts; D011134:Polysaccharides; D000481:Allantoin; D014222:Triamcinolone Acetonide