title: Osseointegration: biological events in relation to characteristics of the implant surface.
abstract: Osseointegration of titanium implants is a complex biological process involving interactions between immuno-inflammatory responses, angiogenesis and osteogenesis, all of which are influenced by the physical and chemical characteristics of the implant surface. An implant surface with moderately rough topography and high surface energy influences cellular activities, enhancing peri-implant bone wound healing. Primary mechanical stability of the implant is essential for osseointegration. In this article we review some of the more important biological events of peri-implant bone wound healing in the process of osseointegration, and discuss how the biophysical properties of implant surfaces influence cellular responses.
authors: L
authors: L
authors: Feller
authors: R
authors: R
authors: Chandran
authors: R A G
authors: RA
authors: Khammissa
authors: R
authors: R
authors: Meyerov
authors: Y
authors: Y
authors: Jadwat
authors: M
authors: M
authors: Bouckaert
authors: I
authors: I
authors: Schechter
authors: J
authors: J
authors: Lemmer
mesh_terms: D001842:Bone and Bones / Q000502:physiology*; D015921:Dental Implants; D003764:Dental Materials / Q000737:chemistry*; D006801:Humans; D016348:Osseointegration / Q000502:physiology*; D010012:Osteogenesis / Q000502:physiology; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry; D014945:Wound Healing / Q000502:physiology
chemical_list: D015921:Dental Implants; D003764:Dental Materials; D014025:Titanium