title: Catheter-related bloodstream infections caused by Trichosporon species.
abstract: Trichosporonosis is an emerging invasive opportunistic fungal infection in immunocompromised patients. We report 5 catheter related blood stream infections caused by Trichosporon species over a five-year period at King Chulalongkorn Memorial Hospital, Bangkok, Thailand. All the patients were immunocompromised, had received broad-spectrum antibiotics and had a central venous catheter or arterial line inserted for a mean duration of 16.2 days (range 10-30 days). Four patients developed disseminated infection and only 2 survived, giving a mortality rate of 60%. Because of the prevalence of Trichosporon catheter related blood stream infections at our institute, health care providers should have a high index of suspicion for Trichosporon species infections in patients with risk factors and prolonged presence of a central venous catheter.
authors: Ratima
authors: R
authors: Issarachaikul
authors: Orapin
authors: O
authors: Lertwannawit
authors: Pitaks
authors: P
authors: Detporntewan
authors: Noppacharn
authors: N
authors: Uaprasert
authors: Rongpong
authors: R
authors: Plongla
authors: Shanop
authors: S
authors: Shuangshoti
authors: Ariya
authors: A
authors: Chindamporn
authors: Chusana
authors: C
authors: Suankratay
mesh_terms: D000328:Adult; D000369:Aged, 80 and over; D000935:Antifungal Agents / Q000627:therapeutic use; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D016469:Fungemia / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D008297:Male; D014250:Trichosporon / Q000302:isolation & purification*; D060586:Trichosporonosis / Q000188:drug therapy / Q000209:etiology*
chemical_list: D000935:Antifungal Agents