title: [Disseminated intravascular coagulation in solid tumours].
abstract: Disseminated intravascular coagulation (DIC) is a complex abnormality of hemostasis with dramatic consequences and long described as associated with tumors. Yet the diagnosis and management of paraneoplastic DIC are poorly defined. The purpose of this paper is to review DIC associated with solid tumors, at the pathophysiological and therapeutic levels in particular. We also report data from a recent retrospective series of patients with DIC in the context of a solid tumor, to illustrate the epidemiological, clinical and prognostic.
authors: Hôpital du Val-de-Grâce, département d'oncologie-radiothérapie, boulevard du Port-Royal, 75005 Paris, France, Institut Gustave Roussy, département d'anesthésie-réanimation, Villejuif, France.
authors: François Régis
authors: FR
authors: Ferrand
authors: Hôpital du Val-de-Grâce, département de biologie, France.
authors: Carine
authors: C
authors: Garcia-Hejl
authors: Hôpital du Val-de-Grâce, département d'oncologie-radiothérapie, boulevard du Port-Royal, 75005 Paris, France, Institut National d'Oncologie, Rabat, Maroc.
authors: Yassine
authors: Y
authors: Moussaid
authors: Hôpital du Val-de-Grâce, département d'oncologie-radiothérapie, boulevard du Port-Royal, 75005 Paris, France.
authors: Antoine
authors: A
authors: Schernberg
authors: Institut Curie, département d'oncologie, Paris, France.
authors: François-Clément
authors: FC
authors: Bidard
authors: Hôpital Desgenettes, service d'oncologie, Lyon, France.
authors: Michel
authors: M
authors: Pavic
authors: Hôpital Desgenettes, service d'oncologie, Lyon, France.
authors: Safia
authors: S
authors: Khenifer
authors: Institut Gustave Roussy, département d'anesthésie-réanimation, Villejuif, France.
authors: Annabelle
authors: A
authors: Stoclin
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D001777:Blood Coagulation / Q000502:physiology; D003029:Coagulants / Q000627:therapeutic use; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D015942:Factor VIIa / Q000627:therapeutic use; D006801:Humans; D009369:Neoplasms / Q000097:blood* / Q000473:pathology / Q000628:therapy; D010257:Paraneoplastic Syndromes / Q000097:blood / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D017713:Platelet Transfusion; D011379:Prognosis; D011994:Recombinant Proteins / Q000627:therapeutic use; D012307:Risk Factors
chemical_list: D000925:Anticoagulants; D003029:Coagulants; D011994:Recombinant Proteins; C103587:recombinant FVIIa; D015942:Factor VIIa
keywords: cancer; disseminated intravascular coagulation; paranéoplastic syndrom