title: A general framework for wireless capsule endoscopy study synopsis.
abstract: We present a general framework for analysis of wireless capsule endoscopy (CE) studies. The current available workstations provide a time-consuming and labor-intense work-flow for clinicians which requires the inspection of the full-length video. The development of a computer-aided diagnosis (CAD) CE workstation will have a great potential to reduce the diagnostic time and improve the accuracy of assessment. We propose a general framework based on hidden Markov models (HMMs) for study synopsis that forms the computational engine of our CAD workstation. Color, edge and texture features are first extracted and analyzed by a Support Vector Machine classifier, and then encoded as the observations for the HMM, uniquely combining the temporal information during the assessment. Experiments were performed on 13 full-length CE studies, instead of selected images previously reported. The results (e.g. 0.933 accuracy with 0.933 recall for detection of polyps) show that our framework achieved promising performance for multiple classification. We also report the patient-level CAD assessment of complete CE studies for multiple abnormalities, and the patient-level validation demonstrates the effectiveness and robustness of our methods.
authors: The Chinese University of Hong Kong, Shatin, Hong Kong; Johns Hopkins University (JHU), Baltimore, MD 21218, USA. Electronic address: qzhao@alumni.ee.cuhk.edu.hk.
authors: Qian
authors: Q
authors: Zhao
authors: Johns Hopkins University (JHU), Baltimore, MD 21218, USA.
authors: Gerard E
authors: GE
authors: Mullin
authors: The Chinese University of Hong Kong, Shatin, Hong Kong.
authors: Max Q-H
authors: MQ
authors: Meng
authors: Washington University School of Medicine, St. Louis, MO 63110, USA.
authors: Themistocles
authors: T
authors: Dassopoulos
authors: Johns Hopkins University (JHU), Baltimore, MD 21218, USA.
authors: Rajesh
authors: R
authors: Kumar
mesh_terms: D000465:Algorithms; D053704:Capsule Endoscopy / Q000379:methods*; D003108:Colonic Diseases / Q000473:pathology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D000069550:Machine Learning; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
keywords: Computer-aided diagnosis; Hidden Markov models; Study synopsis; Supervised classification; Support vector machines; Wireless capsule endoscopy