title: Electrocatalytic oxidation and voltammetric determination of ciprofloxacin employing poly(alizarin red)/graphene composite film in the presence of ascorbic acid, uric acid and dopamine.
abstract: A glassy carbon electrode modified with poly(alizarin red)/electrodeposited graphene (PAR/EGR) composite film was prepared and applied to detect ciprofloxacin (CPFX) in the presence of ascorbic, uric acid and dopamine. The morphology and interface property of PAR/EGR films were examined by scanning electron microscopy (SEM) and electrochemical impedance spectroscopy (EIS). The electrocatalytic oxidation of CPFX on AR/EGR was investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The linearity ranged from 4 × 10(-8) to 1.2 × 10(-4) M with a detection limit (S/N=3) of 0.01 μM. The modified electrode could be applied to the individual determination of CPFX as well as the simultaneous determination of CPFX, ascorbic acid, uric acid and dopamine. This method proved to be a simple, selective and rapid way to determine CPFX in pharmaceutical preparation and biological media.
authors: Department of Chemistry, Shanghai University, Shanghai 200444, PR China.
authors: Xin
authors: X
authors: Zhang
authors: Department of Chemistry, Shanghai University, Shanghai 200444, PR China.
authors: Youli
authors: Y
authors: Wei
authors: Department of Chemistry, Shanghai University, Shanghai 200444, PR China. Electronic address: wdingyp@sina.com.
authors: Yaping
authors: Y
authors: Ding
mesh_terms: D000880:Anthraquinones / Q000737:chemistry*; D001205:Ascorbic Acid / Q000032:analysis* / Q000097:blood; D002939:Ciprofloxacin / Q000032:analysis* / Q000097:blood; D004298:Dopamine / Q000032:analysis* / Q000097:blood; D055664:Electrochemical Techniques / Q000379:methods*; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D010084:Oxidation-Reduction; D014527:Uric Acid / Q000032:analysis* / Q000097:blood
chemical_list: D000880:Anthraquinones; D014527:Uric Acid; D002939:Ciprofloxacin; C010078:alizarin; D006108:Graphite; D001205:Ascorbic Acid; D004298:Dopamine
keywords: Alizarin red; Ciprofloxacin; Potentiostatically electrodeposited graphene; Simultaneously detection