title: Integrins LFA-1 and Mac-1 and cytokines IL-6 and IL-10 in high-cancer mice under the influence of phytoadaptogen.
abstract: The expression of leukocyte integrins LFA-1 and Mac-1 and cytokines IL-6 and IL-10 was studied in mice predisposed to spontaneous hepatocarcinomas. The efficacy of a phytoadaptogen in correcting these parameters was evaluated. The role of adhesive interactions between immune cells and target cells in the recovery of antitumor regulatory mechanisms was estimated.
authors: N. N. Blokhin Russian Research Center of Oncology, Russian Academy of Medical Sciences, Moscow, Russia, imufarm@rambler.ru.
authors: O A
authors: OA
authors: Bocharova
authors: E V
authors: EV
authors: Bocharov
authors: R V
authors: RV
authors: Karpova
authors: V A
authors: VA
authors: Il'enko
authors: I V
authors: IV
authors: Kazeev
authors: A Yu
authors: AY
authors: Baryshnikov
mesh_terms: D000818:Animals; D002448:Cell Adhesion / Q000187:drug effects; D018197:Hepatoblastoma / Q000097:blood / Q000378:metabolism; D016753:Interleukin-10 / Q000097:blood*; D015850:Interleukin-6 / Q000097:blood*; D016169:Lymphocyte Function-Associated Antigen-1 / Q000378:metabolism*; D016177:Macrophage-1 Antigen / Q000378:metabolism*; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology*
chemical_list: D015850:Interleukin-6; D016169:Lymphocyte Function-Associated Antigen-1; D016177:Macrophage-1 Antigen; C401831:PM 40; D010936:Plant Extracts; D016753:Interleukin-10