title: 1,2,3-Triazoles from carbonyl azides and alkynes: filling the gap.
abstract: Electron deficient azides are challenging substrates in CuAAC reactions. Particularly, when N-carbonyl azides are applied the formation of N-carbonyl triazoles has not yet been observed. We report herein the first example of this class of reaction, with a copper-based system that efficiently enables the synthesis of N-carbamoyl 1,2,3-triazoles by [3+2] cycloaddition of N-carbamoyl azides and alkynes.
authors: Laboratorio de Catálisis Homogénea, Unidad Asociada al CSIC, CIQSO-Centro de Investigación en Química Sostenible and Departamento de Química y Ciencias de los Materiales, Campus de El Carmen s/n, Universidad de Huelva, 21007-Huelva, Spain. perez@dqcm.uhu.es.
authors: Estela
authors: E
authors: Haldón
authors: Eleuterio
authors: E
authors: Álvarez
authors: M Carmen
authors: MC
authors: Nicasio
authors: Pedro J
authors: PJ
authors: Pérez
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D061565:Cycloaddition Reaction; D014230:Triazoles / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001386:Azides; D014230:Triazoles; D003300:Copper