title: Safety and efficacy of an intraocular Fresnel prism intraocular lens in patients with advanced macular disease: initial clinical experience.
abstract: OBJECTIVE
  To perform a pilot study of a new in-the-bag Fresnel prism intraocular lens (IOL) designed to deviate the image from diseased to healthy retina in eyes with bilateral age-related macular degeneration (AMD).
  
  
  METHODS
  Anterior segment subspeciality practice, Pretoria, South Africa.
  
  
  METHODS
  Prospective nonmasked trial.
  
  
  METHODS
  Cataract surgery and unilateral implantation of the prismatic IOL were performed in patients with bilateral AMD and cataract. Outcomes were surgical complications, subjective and objective visual improvement, and undesirable optical effects.
  
  
  RESULTS
  Three eyes of 3 patients were evaluated. All patients reported displacement of the scotoma, and no patient reported diplopia. The only complication was posterior capsule opacification (1 eye).
  
  
  CONCLUSIONS
  Patients noted improved vision and no diplopia. This pilot was performed using a prototype IOL with single power and single angle of deviation; however, there is scope for individual patient optimization. This new technology merits further research and development because it may benefit large numbers of patients with stable end-stage AMD.
  
  
  BACKGROUND
  Dr. Claoué has a financial interest in the patent controlling the Fresnel prism IOL. Dr. Potgieter has no financial or proprietary interest in any material or method mentioned.
authors: From the Optimed Eye & Laser Centre (Potgieter), Pretoria, South Africa, and Queen's Hospital (Claoué), Barking Havering and Redbridge University Hospitals, London, United Kingdom.
authors: Frederik J
authors: FJ
authors: Potgieter
authors: From the Optimed Eye & Laser Centre (Potgieter), Pretoria, South Africa, and Queen's Hospital (Claoué), Barking Havering and Redbridge University Hospitals, London, United Kingdom. Electronic address: eyes@dbcg.co.uk.
authors: Charles M P
authors: CM
authors: Claoué
mesh_terms: D000368:Aged; D002386:Cataract / Q000150:complications* / Q000503:physiopathology; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008268:Macular Degeneration / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D010865:Pilot Projects; D011183:Postoperative Complications; D011446:Prospective Studies; D011474:Prosthesis Design; D012029:Refraction, Ocular / Q000502:physiology; D016896:Treatment Outcome; D014786:Vision Disorders / Q000503:physiopathology; D014792:Visual Acuity / Q000502:physiology