title: Myofibroblasts in oral lesions: A review.
abstract: Myofibroblasts (MFs) are modified fibroblasts that express features of smooth muscle differentiation and were first observed in granulation tissue during wound healing. These cells play a key role in physiologic and pathologic processes like wound healing and tumorigenesis. The presence of MFs has been reported in normal oral tissues and pathologic conditions like reactive lesions, benign tumors, locally aggressive tumors and malignancies affecting the oral cavity. This article briefly reviews the important hallmarks related to the discovery, characterization and tissue distribution of MFs in oral health and disease.
authors: Department of Oral and Maxillofacial Pathology, Drs Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Gannavaram, Krishna District, Andhra Pradesh, India.
authors: Soujanya
authors: S
authors: Pinisetti
authors: Vishnu Dental College, Bhimavaram, West Godavari, Andhra Pradesh, India.
authors: Ravikanth
authors: R
authors: Manyam
authors: Department of Oral and Maxillofacial Pathology, Drs Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Gannavaram, Krishna District, Andhra Pradesh, India.
authors: Babburi
authors: B
authors: Suresh
authors: Department of Oral and Maxillofacial Pathology, Drs Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Gannavaram, Krishna District, Andhra Pradesh, India.
authors: V
authors: V
authors: Aparna
keywords: Myofibroblast; oral health and disease; oral lesions; tumorigenesis; wound healing