title: Coexistence of papillary thyroid cancer and Hashimoto thyroiditis in children: report of 3 cases.
abstract: This report documents 3 pediatric papillary thyroid carcinoma cases with associated Hashimoto thyroiditis. In all 3 cases, hypoechoic nodules accompanied by multiple echogenic spots were noted on sonography of the thyroid. Hashimoto thyroiditis was suspected on the basis of positive thyroid autoantibody test results and pathologic examinations of thyroidectomy specimens, which revealed chronic thyroiditis with lymphocytic infiltration as the background of papillary thyroid carcinoma development. The potential for papillary carcinoma development warrants close follow-up, and meticulous sonographic examinations must be performed in children with Hashimoto thyroiditis.
authors: Departments of Clinical Laboratory Medicine (H.K., K.O., T.T., N.T., M.K.) and Laboratory Medicine (K.O., M.K.), Saitama Medical Center, and Department of Diagnostic Pathology (N.F., T.T.), Jichi Medical University, Saitama, Japan.
authors: Harumi
authors: H
authors: Koibuchi
authors: Departments of Clinical Laboratory Medicine (H.K., K.O., T.T., N.T., M.K.) and Laboratory Medicine (K.O., M.K.), Saitama Medical Center, and Department of Diagnostic Pathology (N.F., T.T.), Jichi Medical University, Saitama, Japan. kiyoka@jichi.ac.jp.
authors: Kiyoka
authors: K
authors: Omoto
authors: Departments of Clinical Laboratory Medicine (H.K., K.O., T.T., N.T., M.K.) and Laboratory Medicine (K.O., M.K.), Saitama Medical Center, and Department of Diagnostic Pathology (N.F., T.T.), Jichi Medical University, Saitama, Japan.
authors: Noriyoshi
authors: N
authors: Fukushima
authors: Departments of Clinical Laboratory Medicine (H.K., K.O., T.T., N.T., M.K.) and Laboratory Medicine (K.O., M.K.), Saitama Medical Center, and Department of Diagnostic Pathology (N.F., T.T.), Jichi Medical University, Saitama, Japan.
authors: Tomonori
authors: T
authors: Toyotsuji
authors: Departments of Clinical Laboratory Medicine (H.K., K.O., T.T., N.T., M.K.) and Laboratory Medicine (K.O., M.K.), Saitama Medical Center, and Department of Diagnostic Pathology (N.F., T.T.), Jichi Medical University, Saitama, Japan.
authors: Nobuyuki
authors: N
authors: Taniguchi
authors: Departments of Clinical Laboratory Medicine (H.K., K.O., T.T., N.T., M.K.) and Laboratory Medicine (K.O., M.K.), Saitama Medical Center, and Department of Diagnostic Pathology (N.F., T.T.), Jichi Medical University, Saitama, Japan.
authors: Mikihiko
authors: M
authors: Kawano
mesh_terms: D000293:Adolescent; D044963:Biopsy, Fine-Needle; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000453:epidemiology* / Q000473:pathology; D002291:Carcinoma, Papillary; D002648:Child; D015897:Comorbidity; D005260:Female; D050031:Hashimoto Disease / Q000000981:diagnostic imaging* / Q000453:epidemiology* / Q000473:pathology; D006801:Humans; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000453:epidemiology* / Q000473:pathology; D014463:Ultrasonography
keywords: Hashimoto thyroiditis; children; fine-needle aspiration; papillary thyroid carcinoma; sonography; superficial structures