title: Sleep quality and its correlation with serum C-reactive protein level in hemodialysis patients.
abstract: Poor sleep quality is a common problem that can potentially predict mortality risk and quality of life in hemodialysis (HD) patients. Also, inflammation is a common feature in HD patients. To determine sleep quality and its correlation with serum C-reactive protein (CRP) level in these patients, we studied 132 chronic HD patients in two university-affiliated teaching hospitals in Sari, Iran during September 2010. Pittsburgh Sleep Quality Index was employed to assess the sleep quality of the patients in addition to CRP, albumin, cholesterol, phosphorus and hemoglobin levels. There were 104 (78.7%) patients who suffered from poor sleep quality. A significant correlation was found between serum CRP level and the patients' sleep quality (P <0.05). There was also a significant correlation between sleep quality and serum phosphorus and albumin levels and body mass index (P <0.05). Furthermore, a significant positive correlation existed between the different components of sleep quality and CRP (P <0.05). We conclude that there is a correlation between decreased sleep quality in HD patients and elevated CRP levels, which may have therapeutic implications.
authors: Amir
authors: A
authors: Emami Zeydi
authors: Yadollah
authors: Y
authors: Jannati
authors: Department of Nursing, Islamic Azad University, Sari Branch, Sari, Iran.
authors: Hadi
authors: H
authors: Darvishi Khezri
authors: Afshin
authors: A
authors: Gholipour Baradari
authors: Fatemeh
authors: F
authors: Espahbodi
authors: Mojgan
authors: M
authors: Lesani
authors: Tahereh
authors: T
authors: Yaghoubi
mesh_terms: D000368:Aged; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis*; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D018836:Inflammation Mediators / Q000097:blood*; D007492:Iran; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*; D051436:Renal Insufficiency, Chronic / Q000097:blood / Q000150:complications / Q000628:therapy*; D012307:Risk Factors; D012890:Sleep; D012893:Sleep Wake Disorders / Q000097:blood / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D011795:Surveys and Questionnaires; D013997:Time Factors; D015854:Up-Regulation
chemical_list: D015415:Biomarkers; D018836:Inflammation Mediators; D002097:C-Reactive Protein