title: Assessment of growth dynamics of human cranium middle fossa in foetal period.
abstract: BACKGROUND
  Available literature analysis demonstrated smallness of studies of cranial base.
  
  
  OBJECTIVE
  The goal of the study was to analyse the medial fossa of the human cranium in the foetal period against other fossae.
  
  
  METHODS
  Survey material consisted of 110 human foetuses at a morphological age of 16-28 weeks of foetal life, CRL 98-220 mm. Anthropological, preparation method, reverse method and statistical analysis were utilized. The survey incorporated the following computer programmes: Renishaw, TraceSurf, AutoCAD, CATIA. The reverse method seems especially interesting (impression with polysiloxane (silicone elastomer of high adhesive power used in dentistry) with 18 D 4823 activator. Elicited impression accurately reflected complex shape of cranium base.
  
  
  RESULTS
  On assessing the relative rate of cranium medial fossa, the rate was found to be stable (linear model) for the whole of the analysed period and is 0.19%/week, which stands for the gradual and steady growth of the middle fossa in relation to the whole of the cranium base. At the same time, from the 16th till 28th week of foetal life, relative volume of the cranium middle fossa increases more intensively than cranium anterior fossa, whereas the cranium middle fossa volume as compared with the cranium posterior fossa is definitely slower. In the analysed period, the growth rate of the cranium base middle fossa was bigger in the 4th and 5th weeks than in the 6th and 7th weeks of foetal life. The investigations revealed cranium base asymmetry of the left side. Furthermore, the anterior fossae volume on the left side is significantly bigger than the one of the fossae on the right side.
  
  
  CONCLUSIONS
  Volume growth rate is more intensive in the 4th and 5th than in the 6th and 7th weeks of foetal life. In the examined period, the relative growth rate of cranium base middle fossa is 0.19%/week and it is stable - linear model. The study revealed correlations in the form of mathematical models, which enabled foetuses age assessment.
authors: Specialistic Neurological Consulting Room, Żary, Poland.
authors: Andrzej
authors: A
authors: Skomra
authors: Department of Normal Anatomy, Wroclaw Medical University, Poland.
authors: Alicja
authors: A
authors: Kędzia
authors: Institute of Machines Design and Operation, Technical University of Wroclaw, Poland.
authors: Krzysztof
authors: K
authors: Dudek
authors: Designing Department "GBB-PROJEKT", Marszów, Poland.
authors: Wiesław
authors: W
authors: Bogacz
mesh_terms: D002508:Cephalometry; D035301:Cranial Fossa, Middle / Q000196:embryology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007091:Image Processing, Computer-Assisted; D016014:Linear Models; D008297:Male; D008953:Models, Anatomic; D016628:Replica Techniques