title: Similar physiological effects in Porphyromonas gingivalis ATCC 33277 under hemin-excess and hemin-limited concentrations are putatively associated to different hydrogen peroxide function.
abstract: Porphyromonas gingivalis requires optimal hemin to grow while non-optimal hemin hampers growth. Hemin induces H2O2 production while H2O2 has a dual function. In P. gingivalis ATCC 33277, we found similar physiological effects under hemin-excess and hemin-limited concentrations which we propose is related to two different functions of the H2O2 molecule.
authors: Department of Microbiology, Nihon University School of Dentistry, Tokyo 101-8310, Japan. Electronic address: marni.cueno@nihon-u.ac.jp.
authors: Marni E
authors: ME
authors: Cueno
authors: Department of Microbiology, Nihon University School of Dentistry, Tokyo 101-8310, Japan.
authors: Muneaki
authors: M
authors: Tamura
authors: Department of Microbiology, Nihon University School of Dentistry, Tokyo 101-8310, Japan.
authors: Manabu
authors: M
authors: Ohya
authors: Department of Microbiology, Nihon University School of Dentistry, Tokyo 101-8310, Japan. Electronic address: ochiai.kuniyasu@nihon-u.ac.jp.
authors: Kuniyasu
authors: K
authors: Ochiai
mesh_terms: D018829:Adhesins, Bacterial / Q000378:metabolism; D002087:Butyrates / Q000378:metabolism; D003546:Cysteine Endopeptidases / Q000378:metabolism; D000080867:Gingipain Cysteine Endopeptidases; D006427:Hemin / Q000378:metabolism*; D006861:Hydrogen Peroxide / Q000378:metabolism*; D016966:Porphyromonas gingivalis / Q000254:growth & development / Q000378:metabolism / Q000502:physiology*; D013312:Stress, Physiological; D013482:Superoxide Dismutase / Q000378:metabolism
chemical_list: D018829:Adhesins, Bacterial; D002087:Butyrates; D000080867:Gingipain Cysteine Endopeptidases; D006427:Hemin; D006861:Hydrogen Peroxide; D013482:Superoxide Dismutase; D003546:Cysteine Endopeptidases
keywords: Hemin; Hydrogen peroxide; Porphyromonas gingivalis ATCC 33277