title: A copper-mediated cross-coupling approach for the synthesis of 3-heteroaryl quinolone and related analogues.
abstract: An efficient and practical method for the direct cross-coupling between quinolones and a range of azoles was developed via copper-mediated C-H functionalization. This synthetic strategy provides a convenient access to a variety of C3-heteroaryl quinolones, quinolinone, nalidixic acid, uracil, pyridone and chromone derivatives, which are prominent structural motifs in many biologically active compounds.
authors: Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 305-701, Korea. hongorg@kaist.ac.kr.
authors: Sanghye
authors: S
authors: Shin
authors: Yechan
authors: Y
authors: Kim
authors: Kiho
authors: K
authors: Kim
authors: Sungwoo
authors: S
authors: Hong
mesh_terms: D052160:Benzothiazoles / Q000737:chemistry; D002625:Chemistry, Organic / Q000379:methods*; D003300:Copper / Q000737:chemistry*; D015363:Quinolones / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D052160:Benzothiazoles; D015363:Quinolones; D003300:Copper