title: Association of diabetic peripheral arterial disease and objectively-measured physical activity: NHANES 2003-2004.
abstract: BACKGROUND
  Although much is known about the management of peripheral arterial disease among adults in the general population, the management of this disease among those with diabetes, and the effects of diabetic-induced peripheral arterial disease on objectively-measured physical activity, is unclear. Here, we examined the association between accelerometer-assessed physical activity and peripheral arterial disease among a national sample of U.S. adults with diabetes.
  
  
  METHODS
  Data from the 2003-2004 National Health and Nutrition Examination Survey were used. Physical activity was measured using an accelerometer in 254 adults with diabetes. Peripheral arterial disease was assessed via ankle brachial index. Negative binomial regression analysis was used to examine the association between physical activity and peripheral arterial disease.
  
  
  RESULTS
  Results were adjusted for age, gender, race-ethnicity, comorbidity index, smoking, HgbA1C, C-reactive protein, homocysteine, glomerular filtration rate, microalbuminuria, peripheral neuropathy, physical functioning, and medication use. After adjustments, participants with peripheral arterial disease engaged in 23% less physical activity (RR = 0.77, 95% CI: 0.62-0.96) than those without peripheral arterial disease.
  
  
  CONCLUSIONS
  These findings demonstrate an inverse association between accelerometer-assessed physical activity and peripheral arterial disease in a national sample of U.S adults with diabetes.
authors: Departments of Exercise Science and Physical Therapy, Donna & Allan Lansing School of Nursing & Health Sciences, Bellarmine University, Louisville, KY 40205, USA.
authors: Paul D
authors: PD
authors: Loprinzi
authors: Maricopa Integrated Health System, Phoenix, AZ, USA.
authors: Kalen
authors: K
authors: Abbott
keywords: Accelerometry; Epidemiology; Exercise; National Health and Nutrition Examination Survey (NHANES)