title: The CANadian Pediatric Weight management Registry (CANPWR): study protocol.
abstract: BACKGROUND
  Over recent decades, the prevalence of pediatric obesity has increased markedly in developed and developing countries, and the impact of obesity on health throughout the lifespan has led to urgent calls for action. Family-based weight management interventions that emphasize healthy lifestyle changes can lead to modest improvements in weight status of children with obesity. However, these interventions are generally short in duration, reported in the context of randomized controlled trials and there are few reports of outcomes of these treatment approaches in the clinical setting. Answering these questions is critical for improving the care of children with obesity accessing outpatient health services for weight management. In response, the CANadian Pediatric Weight management Registry (CANPWR) was designed with the following three primary aims: 1. Document changes in anthropometric, lifestyle, behavioural, and obesity-related co-morbidities in children enrolled in Canadian pediatric weight management programs over a three-year period; 2. Characterize the individual-, family-, and program-level determinants of change in anthropometric and obesity-related co-morbidities; 3. Examine the individual-, family-, and program-level determinants of program attrition.
  
  
  METHODS
  This prospective cohort, multi-centre study will include children (2-17 years old; body mass index ≥85(th) percentile) enrolled in one of eight Canadian pediatric weight management centres. We will recruit 1,600 study participants over a three-year period. Data collection will occur at presentation and 6-, 12-, 24-, and 36-months follow-up. The primary study outcomes are BMI z-score and change in BMI z-score over time. Secondary outcomes include anthropometric (e.g., height, waist circumference,), cardiometabolic (e.g., blood pressure, lipid profile, glycemia), lifestyle (e.g., dietary intake, physical activity, sedentary activity), and psychosocial (e.g., health-related quality of life) variables. Potential determinants of change and program attrition will include individual-, family-, and program-level variables.
  
  
  CONCLUSIONS
  This study will enable our interdisciplinary team of clinicians, researchers, and trainees to address foundational issues regarding the management of pediatric obesity in Canada. It will also serve as a harmonized, evidence-based registry and platform for conducting future intervention research, which will ultimately enhance the weight management care provided to children with obesity and their families.
authors: Department of Pediatrics, McMaster Children's Hospital, McMaster University, Hamilton, ON, Canada. kmorrison@mcmaster.ca.
authors: Katherine M
authors: KM
authors: Morrison
authors: Samah
authors: S
authors: Damanhoury
authors: Annick
authors: A
authors: Buchholz
authors: Jean-Pierre
authors: JP
authors: Chanoine
authors: Marie
authors: M
authors: Lambert
authors: Mark S
authors: MS
authors: Tremblay
authors: Glenn
authors: G
authors: Berall
authors: Jill
authors: J
authors: Hamilton
authors: Anne Marie
authors: AM
authors: Laberge
authors: Laurent
authors: L
authors: Legault
authors: Lehana
authors: L
authors: Thabane
authors: Monica
authors: M
authors: Jakymyshyn
authors: Kathryn A
authors: KA
authors: Ambler
authors: Geoff D C
authors: GD
authors: Ball
mesh_terms: D000293:Adolescent; D000886:Anthropometry; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D015992:Body Mass Index; D002170:Canada; D002648:Child; D002675:Child, Preschool; D015438:Health Behavior; D006801:Humans; D008019:Life Style; D008055:Lipids / Q000032:analysis; D010349:Patient Compliance; D063766:Pediatric Obesity / Q000517:prevention & control*; D011446:Prospective Studies; D011788:Quality of Life; D012042:Registries; D061217:Weight Reduction Programs
chemical_list: D001786:Blood Glucose; D008055:Lipids