title: [Chemical constituents from the roots of Ilex pubescens].
abstract: OBJECTIVE
  To study the chemical constituents from the roots of Ilex pubescens.
  
  
  METHODS
  The 95% ethanol extract of the plant was separated by silica gel, Sephadex LH-20 and preparative HPLC chromatography. The structures were elucidated based on the physiochemical properties and spectroscopic analysis.
  
  
  RESULTS
  Fifteen compounds were isolated and identified as oleuropein(1), oleoside dimethyl ester(2),8 (Z)-nuezhenide(3),3,4-dicaffeoylquinic acid methyl ester(4),3,4,5-tricaffeoylquinic acid methyl ester (5), isovanillic acid(6), syringic acid(7), 3beta-acetyloleanolic acid (8), 3beta-acetylursolic acid(9), uvaol(10), asiatic acid(11), 2alpha-hydroxyursolic acid(12), oleanolic acid (13), ursolic acid (14), stigmasterol-3-O-beta-D-glucopyranoside (15).
  
  
  CONCLUSIONS
  Compounds 2,3,8,9 are obtained from this genus for the first time,compounds 5-7,10-12 are isolated from this plant for the first time.
authors: Yi-ping
authors: YP
authors: Jiang
authors: Hua
authors: H
authors: Li
authors: Xue-zhi
authors: XZ
authors: Pan
authors: Xue-gang
authors: XG
authors: Sun
authors: Qing-fa
authors: QF
authors: Tang
authors: Meng
authors: M
authors: Shao
mesh_terms: D002726:Chlorogenic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D002851:Chromatography, High Pressure Liquid; D005707:Gallic Acid / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D030017:Ilex / Q000737:chemistry*; D053978:Pentacyclic Triterpenes / Q000737:chemistry / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry*; D011801:Quinic Acid / Q000031:analogs & derivatives; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification; D014641:Vanillic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification
chemical_list: C412810:2-hydroxyursolic acid; D053978:Pentacyclic Triterpenes; D014315:Triterpenes; C472707:caffeoylquinic acid; D011801:Quinic Acid; D002726:Chlorogenic Acid; D005707:Gallic Acid; C045317:isovanillic acid; C017032:asiatic acid; C001945:syringic acid; D014641:Vanillic Acid; C013330:uvaol