title: Scalable, transition-metal-free direct oxime O-arylation: rapid access to O-arylhydroxylamines and substituted benzo[b]furans.
abstract: O-aryloximes, generated from readily available and inexpensive oximes through transition-metal-free O-arylation, can either be hydrolyzed to O-arylhydroxylamines or conveniently converted to structurally diverse benzo[b]furans through an environmentally benign, one-pot [3,3]-sigmatropic rearrangement/cyclization sequence.
authors: Division of Chemistry, Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390 (USA), Fax: (+1) 617-812-2685.
authors: Hongyin
authors: H
authors: Gao
authors: Qing-Long
authors: QL
authors: Xu
authors: Craig
authors: C
authors: Keene
authors: László
authors: L
authors: Kürti
mesh_terms: D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D019811:Hydroxylamine / Q000138:chemical synthesis* / Q000737:chemistry; D010091:Oximes / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D001572:Benzofurans; D010091:Oximes; D019811:Hydroxylamine
keywords: O-arylation; benzofurans; cyclization; diaryliodonium salts; oximes; sigmatropic rearrangement; transition-metal free