title: Diversity of Francisella tularensis subsp. holarctica lineages, China.
abstract: We analyzed 10 isolates of Francisella tularensis subspecies holarctica from China and assigned them to known clades by using canonical single-nucleotide polymorphisms. We found 4 diverse subtypes, including 3 from the most basal lineage, biovar japonica. This result indicates unprecedented levels of diversity from a single region and suggests new models for emergence.
authors: Yanhua
authors: Y
authors: Wang
authors: Yao
authors: Y
authors: Peng
authors: Rong
authors: R
authors: Hai
authors: Lianxu
authors: L
authors: Xia
authors: Hang
authors: H
authors: Li
authors: Zhikai
authors: Z
authors: Zhang
authors: Hong
authors: H
authors: Cai
authors: Ying
authors: Y
authors: Liang
authors: Xiaona
authors: X
authors: Shen
authors: Dongzheng
authors: D
authors: Yu
authors: Dawn
authors: D
authors: Birdsell
authors: David M
authors: DM
authors: Wagner
authors: Paul
authors: P
authors: Keim
mesh_terms: D002681:China; D005604:Francisella tularensis / Q000235:genetics*; D006801:Humans; D010802:Phylogeny; D058974:Phylogeography / Q000379:methods; D020641:Polymorphism, Single Nucleotide / Q000235:genetics; D014406:Tularemia / Q000382:microbiology
keywords: China; Francisella tularensis subsp. holarctica; SNP; bacteria; canSNP; lineage; phylogeography; tularemia