title: [Role of Wnt/β-catenin signaling pathway in promoting tumorigenesis of hepatocellular carcinoma].
abstract: Wnt/β-catenin signaling pathway has a close relationship with cancer and is abnormally activated in many human cancers. Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death worldwide, but the molecular mechanisms of HCC are still poorly understood. Current studies indicate that Wnt/β-catenin signaling pathway plays a key role in the development and progression of HCC. Validating the role and mechanism of Wnt/β-catenin signaling pathway in HCC will provide a theoretical basis for early diagnosis and treatment of HCC. In this review, we summarize the role of Wnt/β-catenin signaling pathway in HCC and the progress of current researches.
authors: Beilun District TCM hospital, Ningbo 315800, China.
authors: Lianghai
authors: L
authors: Xie
authors: Han
authors: H
authors: Jiang
authors: Fusheng
authors: F
authors: Wu
mesh_terms: D063646:Carcinogenesis; D006528:Carcinoma, Hepatocellular; D006801:Humans; D008113:Liver Neoplasms; D051153:Wnt Proteins; D060449:Wnt Signaling Pathway; D051176:beta Catenin
chemical_list: D051153:Wnt Proteins; D051176:beta Catenin