title: Extended maternal age at birth of last child and women's longevity in the Long Life Family Study.
abstract: OBJECTIVE
  This study investigated the association between maternal age at birth of last child and likelihood of survival to advanced age.
  
  
  METHODS
  This was a nested case-control study using Long Life Family Study data. Three hundred eleven women who survived past the oldest 5th percentile of survival (according to birth cohort-matched life tables) were identified as cases, and 151 women who died at ages younger than the top 5th percentile of survival were identified as controls. A Bayesian mixed-effect logistic regression model was used to estimate the association between maternal age at birth of last child and exceptional longevity among these 462 women.
  
  
  RESULTS
  We found a significant association for older maternal age, whereby women who had their last child beyond age 33 years had twice the odds for survival to the top 5th percentile of survival for their birth cohorts compared with women who had their last child by age 29 years (age between 33 and 37 y: odds ratio, 2.08; 95% CI, 1.13 to 3.92; older age: odds ratio, 1.92; 95% CI, 1.03 to 3.68).
  
  
  CONCLUSIONS
  This study supports findings from other studies demonstrating a positive association between older maternal age and greater odds for surviving to an unusually old age.
authors: From the 1Department of Biostatistics, School of Public Health, Boston University, Boston, MA; 2Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; 3New England Centenarian Study, Geriatrics Section, School of Medicine, Boston University Medical Center, Boston, MA; 4Division of Biostatistics, Washington University in St Louis, St Louis, MO; and 5Population Studies Center, University of Pennsylvania, Philadelphia, PA.
authors: Fangui
authors: F
authors: Sun
authors: Paola
authors: P
authors: Sebastiani
authors: Nicole
authors: N
authors: Schupf
authors: Harold
authors: H
authors: Bae
authors: Stacy L
authors: SL
authors: Andersen
authors: Avery
authors: A
authors: McIntosh
authors: Haley
authors: H
authors: Abel
authors: Irma T
authors: IT
authors: Elo
authors: Thomas T
authors: TT
authors: Perls
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003718:Denmark; D004522:Educational Status; D005260:Female; D006801:Humans; D008136:Longevity / Q000502:physiology*; D008137:Longitudinal Studies; D008423:Maternal Age; D016017:Odds Ratio; D011247:Pregnancy; D012907:Smoking; D014481:United States