title: Unusual cases of pigmented villonodular synovitis after arthroplasty.
abstract: Pigmented Villonodular Synovitis (PVNS) is a relatively rare, benign proliferation lesion of the synovium of large joints. The etiology is varied and unclear. We had report a 79-year-old woman had PVNS after 14 years right hip arthroplasty with metal prosthesis. Here we report another 4 patients had PVNS after arthroplasty. The second one had PVNS in the 2(th) year after hip arthroplasty with bone cement prosthesis. The specimen was brown and like usual PVNS in tissue. The third case had PVNS in the 8(th) after arthroplasty with human bone prosthesis because of the recurrence of PVNS. The proliferated synovium became black from brown. There was brown and many groups black pigment in the tissue. The fourth one had PVNS in the 4(th) year after knee arthroplasty with polyethylene prosthesis. The specimen was yellow. There was no pigment in the tissue but multinucleated giant cells with unstained foreign body. The fifth patient had PVNS in the 10(th) month after the left hip arthroplasty with metal prosthesis. The macroscopy was yellow. There were hemosiderin particles in the tissue but black metal particles. This indicates that arthroplasty with prosthesis could cause some new disease or PVNS had new etiology with different pathological show.
authors: Department of Pathology, Changzheng Hospital, Second Military Medical University Shanghai, China.
authors: Xiao-Mei
authors: XM
authors: Ma
authors: Department of Pathology, Changzheng Hospital, Second Military Medical University Shanghai, China.
authors: Chun-Yan
authors: CY
authors: Xia
authors: Department of Osteology, Changzheng Hospital, Second Military Medical University Shanghai, China.
authors: Pei-Liang
authors: PL
authors: Fu
authors: Department of Pathology, Changzheng Hospital, Second Military Medical University Shanghai, China.
authors: Hui-Min
authors: HM
authors: Liu
authors: Department of Pathology, Changzheng Hospital, Second Military Medical University Shanghai, China.
authors: Hong-Yu
authors: HY
authors: Yu
authors: Department of Pathology, Changzheng Hospital, Second Military Medical University Shanghai, China.
authors: Jin
authors: J
authors: He
keywords: Pigmented villonodular synovitis; arthroplasty; etiology