title: Pulp response to dentine adhesives: A study on mature human pulps.
abstract: OBJECTIVE
  To clinically investigate the antibacterial effects of a commercially available self-etch 12-methacryloyloxy- dodecylpyridinium bromide (MDPB)-containing adhesive system in comparison with its respective non-MDPB-containing adhesive and to evaluate the pulp responses when in use on human teeth.
  
  
  METHODS
  Sixty-two viable human teeth scheduled for extraction were used. Class V cavities were prepared on the buccal surfaces of the teeth and filled with the tested materials (Protect Bond/Clearfil AP-X, SE Bond/Clearfil AP-X and Dycal/Ketac Fill Plus) as a control group, according to manufacturer's recommendations. Randomly divided to two groups teeth remained intra-orally for 4 and 8 weeks. After extraction, teeth were decalcified, sectioned and stained using the Mayer's hematoxylin and eosin, and modified Brown-Brenn's technique. Pulp responses were evaluated microscopically under a microscope and remaining dentine thickness measured under a stereomicroscope.
  
  
  RESULTS
  No statistically significant differences regarding pulp inflammation or bacterial infiltration were found either for the materials tested or for periods of post-operative evaluation.
  
  
  CONCLUSIONS
  The results suggested that for a short period of evaluation there are no quantitative differences, regardless to restoring material used.
authors: Department of Operative Dentistry, Faculty of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors: Pantelis
authors: P
authors: Kouros
authors: Department of Operative Dentistry, Faculty of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors: Eugenia
authors: E
authors: Koliniotou-Koumpia
authors: Department of Operative Dentistry, Faculty of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors: Elisabeth
authors: E
authors: Koulaouzidou
authors: Department of Operative Dentistry, Faculty of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors: Maria
authors: M
authors: Helvatjoglu-Antoniades
authors: Department of Endodontology, Faculty of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors: Dimitrios
authors: D
authors: Tziafas
keywords: 12-methacryloyloxydodecylpyridinium bromide; Adhesive; antibacterial; dentine; pulp