title: Performance of the Cepheid Xpert® SA Nasal Complete PCR assay compared to culture for detection of methicillin-sensitive and methicillin-resistant Staphylococcus aureus colonization.
abstract: Sensitivity, specificity, positive predictive value, and negative predictive value for the Cepheid Xpert® SA Nasal Complete detection (N = 971) of methicillin-sensitive Staphylococcus aureus was 86.5%, 98.5%, 94.6%, and 96.1%; detection of methicillin-resistant S. aureus was 89.3%, 97.9%, 79.8%, and 99.0%, respectively. Our results show that testing on long-term care facility patients had lower sensitivity and specificity compared to acute care patient results.
authors: NorthShore University Health System, Evanston, IL. Electronic address: ppatel@northshore.org.
authors: Parul A
authors: PA
authors: Patel
authors: NorthShore University Health System, Evanston, IL.
authors: Donna M
authors: DM
authors: Schora
authors: NorthShore University Health System, Evanston, IL.
authors: Kari E
authors: KE
authors: Peterson
authors: NorthShore University Health System, Evanston, IL.
authors: Althea
authors: A
authors: Grayes
authors: NorthShore University Health System, Evanston, IL.
authors: Susan
authors: S
authors: Boehm
authors: NorthShore University Health System, Evanston, IL; University of Chicago Pritzker School of Medicine, Chicago, IL.
authors: Lance R
authors: LR
authors: Peterson
mesh_terms: D002353:Carrier State / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus / Q000235:genetics*; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D016133:Polymerase Chain Reaction / Q000379:methods*; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000235:genetics
keywords: MRSA; Methicillin-resistant Staphylococcus aureus; Rapid diagnostics; Real-time PCR; Staphylococcus aureus; Surveillance