title: Microarrays meet the Voltaire challenge: Drug discovery on a chip?
abstract: The co-emergence of microarray technologies with systems oriented approaches to discovery is testament to the technological and conceptual advancements of recent years. By providing a platform for massively parallelized reductionism, microarrays are enabling us to examine the functional features of diverse classes of bio-system components in a contextually meaningful manner. Yet, to provide economic impact, future development of these technologies demands intimate alignment with the goal of producing safer and more efficacious drugs.:
authors: Theoretical Bioinformatics, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. Electronic address:d.jackson@dkfz.de.
authors: David B
authors: DB
authors: Jackson
authors: Theoretical Bioinformatics, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
authors: Martin A
authors: MA
authors: Stein
authors: The Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Ireland.
authors: Alejandro
authors: A
authors: Merino
authors: Theoretical Bioinformatics, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
authors: Roland
authors: R
authors: Eils