title: Role of total hip replacement arthroplasty between transplantation and acute kidney injury.
abstract: Osteonecrosis of the femoral head is a severely disabling complication of steroid immunosuppression in renal transplant patients. The increased number of patients undergoing transplantation has increased the number of transplant recipients undergoing total hip replacement arthroplasty (THRA). In this study, we retrospectively assessed patients who underwent THRA from May 2004 to February 2014, and evaluated their demographic and clinical characteristics, the results of peri-operative laboratory tests, the amounts of fluids transfused during surgery, and anesthesia time. Our results found that post-operative acute kidney injury (AKI) was significantly associated with transplantation, and transplantation was an independent factor predictive of post-operative AKI, so transplant recipients are at risk for AKI following THRA. Total hip replacement is a safe and effective treatment for transplant recipients and, in view of their limited life expectancy, should be considered at an early stage in their treatment.
authors: Traditional Chinese Medicine-Western Medicine Hospital of Cangzhou of Hebei, Cangzhou City , Hebei Province , China.
authors: Xiaoming
authors: X
authors: Li
authors: Donghui
authors: D
authors: Guo
authors: Guojun
authors: G
authors: Shi
authors: Ruiliang
authors: R
authors: Li
authors: Xiao
authors: X
authors: Li
authors: Ruibin
authors: R
authors: Shen
authors: Hongyu
authors: H
authors: Wang
authors: Yunmei
authors: Y
authors: Li
authors: Fulu
authors: F
authors: Yuan
authors: Guangpu
authors: G
authors: Han
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D000305:Adrenal Cortex Hormones / Q000009:adverse effects; D000328:Adult; D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D005271:Femur Head Necrosis / Q000139:chemically induced / Q000601:surgery; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D008875:Middle Aged; D016377:Organ Transplantation / Q000009:adverse effects*; D011183:Postoperative Complications / Q000209:etiology*; D012189:Retrospective Studies
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents
keywords: AKI; AVN; THRA; recipients; transplantation