title: Pulmonary artery thrombus in a premature neonate treated with recombinant tissue plasminogen activator.
abstract: Pulmonary artery thrombus is a rarely reported complication in premature neonates. The management of life-threatening thrombotic events in neonates is controversial, especially regarding the use of thrombolytics versus anticoagulation alone for treatment. We report a case of a premature neonate with symptomatic pulmonary artery thrombus treated with recombinant tissue plasminogen activator who survived without bleeding complications.
authors: Division of Neonatology, Duke University Medical Center, Durham, NC, USA.
authors: S D
authors: SD
authors: DeMeo
authors: Division of Neonatology, University of North Carolina, Chapel Hill, NC, USA.
authors: A
authors: A
authors: Sherwood
authors: Department of Pharmacy, Duke University Medical Center, Durham, NC, USA.
authors: C D
authors: CD
authors: Hornik
authors: Division of Neonatology, Duke University Medical Center, Durham, NC, USA.
authors: R N
authors: RN
authors: Goldberg
authors: Division of Neonatology, Duke University Medical Center, Durham, NC, USA.
authors: C M
authors: CM
authors: Cotten
authors: Division of Neonatology, Duke University Medical Center, Durham, NC, USA.
authors: M
authors: M
authors: Bidegain
mesh_terms: D015150:Echocardiography, Doppler; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D011651:Pulmonary Artery / Q000473:pathology*; D011994:Recombinant Proteins; D013927:Thrombosis / Q000188:drug therapy*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
chemical_list: D005343:Fibrinolytic Agents; D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator