title: Handling chemotherapy drugs-Do medical gloves really protect?
abstract: Due to their potential mutagenic, carcinogenic and teratogenic effects occupational exposure to chemotherapy drugs should be kept to a minimum. Utilization of personnel protective devices, especially the use of protective medical gloves, is a mainstay to avoid skin contact. The choice of appropriate gloves is of outstanding importance. For optimal protection in the oncology setting it is essential to establish general guidelines evaluating appropriate materials and defining quality standards. Establishing these guidelines can facilitate better handling and avoid potential hazards and late sequelae. In Europe there are no specific requirements or test methodologies for medical gloves used in the oncology environment. The implementation of uniform standards for gloves used while handling chemotherapy drugs would be desirable. In contrast, in the US medical gloves used to handle chemotherapy drugs have to fulfill requirements according to the ASTM International (American Society of Testing and Materials) standard D 6978-05. Nitrile or natural rubber latex is a preferred basic glove material, while vinyl is considered inappropriate because of its generally increased permeability. For extended exposure to chemotherapy drugs, double gloving, the use of thicker gloves and the frequent change of gloves increases their protective power.
authors: Department of Dermatology, Ernst von Bergmann General Hospital, Potsdam, Germany.
authors: Lilla
authors: L
authors: Landeck
authors: Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
authors: Ernesto
authors: E
authors: Gonzalez
authors: Department of Oncology, Klinikum Osnabrück, Osnabrück, Germany.
authors: Olaf Manfred
authors: OM
authors: Koch
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D005060:Europe; D017575:Gloves, Protective / Q000592:standards; D006801:Humans; D007840:Latex; D016273:Occupational Exposure / Q000517:prevention & control*; D017410:Practice Guidelines as Topic; D014481:United States
chemical_list: D000970:Antineoplastic Agents; D007840:Latex
keywords: basic glove materials: latex; chemotherapy drugs; nitrile; prevention in health care workers; speciality patient examination gloves; vinyl