title: An atlas of the nonpolypoid colorectal neoplasms in inflammatory bowel disease.
abstract: The role of endoscopy in the management of patients with inflammatory bowel disease (IBD) is well established. However, recent data have shown significant limitations in the effectiveness of colonoscopy in preventing colorectal cancer (CRC) in patients with IBD colitis. The current standard random biopsy seemed largely ineffective in detecting nonpolypoid colorectal neoplasms. Data using chromoendoscopy with targeted biopsy, however, showed a significant improvement when used to detect dysplasia, the best predictor of CRC risk. This article provides a useful and organized series of images of the detection, diagnosis and management of the superficial elevated, flat, and depressed colorectal neoplasms in IBD patients, and provides a technical guide for the use of chromoendoscopy with targeted biopsy.
authors: Veterans Affairs Palo Alto, Stanford University School of Medicine, 3801 Miranda Avenue, GI 111, Palo Alto, CA 94304, USA. Electronic address: giendo@me.com.
authors: Roy
authors: R
authors: Soetikno
authors: Division of Gastroenterology and Hepatology, GROW, School for Oncology and Developmental Biology, Maastricht University Medical Center, Postbox 5800, 6202 AZ, Maastricht, The Netherlands.
authors: Silvia
authors: S
authors: Sanduleanu
authors: Veterans Affairs Palo Alto, Stanford University School of Medicine, 3801 Miranda Avenue, GI 111, Palo Alto, CA 94304, USA.
authors: Tonya
authors: T
authors: Kaltenbach
mesh_terms: D001706:Biopsy / Q000379:methods; D003106:Colon / Q000473:pathology*; D003113:Colonoscopy / Q000379:methods; D015179:Colorectal Neoplasms / Q000209:etiology / Q000473:pathology*; D004396:Coloring Agents; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000150:complications / Q000473:pathology*; D008488:Medical Illustration; D009361:Neoplasm Invasiveness
chemical_list: D004396:Coloring Agents
keywords: Chromoendoscopy; Colorectal cancer; Inflammatory bowel disease; Nonpolypoid colorectal neoplasms; Surveillance colonoscopy