title: Intravascular papillary endothelial hyperplasia of larynx: case report and literature review of all head and neck cases.
abstract: Intravascular papillary endothelial hyperplasia (IPEH) is a benign lesion of a vascular origin that is caused by excessive proliferation of endothelial cells in blood vessels or vascular malformations. It is a rare entity that can present in any region of the body, but with particular predilection to the head and neck region and the extremities. We also present the results of the English literature search, which to our knowledge are all the published cases of IPEH in the head and neck region (No=213). IPEH has not been reported to arise from the glottic region previously. We present a first case of IPEH arising from the vocal fold of a 48-year-old male. Histological differential diagnosis of IPEH includes several entities, most importantly angiosarcoma. Presentation and histology are discussed. The main treatment option is a complete surgical resection. Prognosis of IPEH is excellent, with the exception of some intracranial cases.
authors: University ENT Department, Medical School of Comenius University and University Hospital Bratislava, Slovakia; ENT Department, University Hospitals Coventry and Warwickshire, University of Warwick, United Kingdom. Electronic address: miro.tedla@gmail.com.
authors: Miroslav
authors: M
authors: Tedla
authors: University ENT Department, Medical School of Comenius University and University Hospital Bratislava, Slovakia; ENT Department, Faculty Hospital Trenčín, Slovakia.
authors: Miroslava
authors: M
authors: Bežová
authors: Histopatológia a.s., Bratislava, Slovakia.
authors: Csaba
authors: C
authors: Biró
authors: Department of Pneumology and Phtiseology, Medical School of Comenius University and University Hospital Bratislava, Slovakia.
authors: Eva
authors: E
authors: Tedlová
authors: ENT Department, Alexandra Hospital, Singapore.
authors: Chee-Yean
authors: CY
authors: Eng
authors: Department of Otolaryngology, University Hospital Ostrava, Czech Republic.
authors: Karol
authors: K
authors: Zeleník
mesh_terms: D003937:Diagnosis, Differential; D006257:Head / Q000473:pathology*; D006801:Humans; D006965:Hyperplasia / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*; D007830:Larynx / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009333:Neck / Q000473:pathology*; D011379:Prognosis
keywords: Glottis; Head and neck; Intravascular papillary endothelial hyperplasia