title: Prevalence and severity of asymptomatic coronary and carotid artery disease in patients with abdominal aortic aneurysm.
abstract: We evaluated the prevalence and severity of occult coronary artery disease (CAD) and cerebrovascular disease (CeVD) in patients with abdominal aortic aneurysm (AAA). We studied 100 consecutive patients with no history of CAD, normal electrocardiogram, normal systolic function, and no angina or dyspnea. All patients underwent carotid Doppler study and invasive coronary angiography. Significant CAD was observed in 61% of patients. In all, 51% of patients with significant CAD showed either left main (n = 7), 3-vessel (n = 17), or proximal left anterior descending (n = 7) CAD, corresponding to 31% of the total cohort. Cerebrovascular disease was detected in 53% of patients, and in 38% of them was significant (peak systolic flow velocity ≥125 <230 cm/s). In 36% of patients with CeVD either left main (n = 5), 3-vessel (n = 11), or proximal left anterior descending (n = 3) CAD was observed. Severe asymptomatic CAD is prevalent in AAA, and 31% of patients fulfill indications for coronary revascularization.
authors: Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
authors: Fabio
authors: F
authors: Marsico
authors: Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
authors: Giuseppe
authors: G
authors: Giugliano
authors: Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
authors: Donatella
authors: D
authors: Ruggiero
authors: Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
authors: Antonio
authors: A
authors: Parente
authors: Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
authors: Stefania
authors: S
authors: Paolillo
authors: Department of Public Health, University of Naples Federico II, Naples, Italy.
authors: Luca Del
authors: LD
authors: Guercio
authors: Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
authors: Giovanni
authors: G
authors: Esposito
authors: Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
authors: Bruno
authors: B
authors: Trimarco
authors: Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy fpperron@unina.it.
authors: Pasquale Perrone
authors: PP
authors: Filardi
mesh_terms: D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000175:diagnosis / Q000453:epidemiology*; D058070:Asymptomatic Diseases; D001783:Blood Flow Velocity; D002340:Carotid Artery Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D016022:Case-Control Studies; D002560:Cerebrovascular Circulation; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000175:diagnosis / Q000453:epidemiology*; D023921:Coronary Stenosis / Q000175:diagnosis / Q000453:epidemiology*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012720:Severity of Illness Index; D018608:Ultrasonography, Doppler
keywords: abdominal aortic aneurysm; cerebrovascular disease; coronary artery disease