title: Evidence-based management of traumatic thoracolumbar burst fractures: a systematic review of nonoperative management.
abstract: OBJECTIVE
  The overall evidence for nonoperative management of patients with traumatic thoracolumbar burst fractures is unknown. There is no agreement on the optimal method of conservative treatment. Recent randomized controlled trials that have compared nonoperative to operative treatment of thoracolumbar burst fractures without neurological deficits yielded conflicting results. By assessing the level of evidence on conservative management through validated methodologies, clinicians can assess the availability of critically appraised literature. The purpose of this study was to examine the level of evidence for the use of conservative management in traumatic thoracolumbar burst fractures.
  
  
  METHODS
  A comprehensive search of the English literature over the past 20 years was conducted using PubMed (MEDLINE). The inclusion criteria consisted of burst fractures resulting from a traumatic mechanism, and fractures of the thoracic or lumbar spine. The exclusion criteria consisted of osteoporotic burst fractures, pathological burst fractures, and fractures located in the cervical spine. Of the studies meeting the inclusion/exclusion criteria, any study in which nonoperative treatment was used was included in this review.
  
  
  RESULTS
  One thousand ninety-eight abstracts were reviewed and 447 papers met inclusion/exclusion criteria, of which 45 were included in this review. In total, there were 2 Level-I, 7 Level-II, 9 Level-III, 25 Level-IV, and 2 Level-V studies. Of the 45 studies, 16 investigated conservative management techniques, 20 studies compared operative to nonoperative treatments, and 9 papers investigated the prognosis of conservative management.
  
  
  CONCLUSIONS
  There are 9 high-level studies (Levels I-II) that have investigated the conservative management of traumatic thoracolumbar burst fractures. In neurologically intact patients, there is no superior conservative management technique over another as supported by a high level of evidence. The conservative technique can be based on patient and surgeon preference, comfort, and access to resources. A high level of evidence demonstrated similar functional outcomes with conservative management when compared with open surgical operative management in patients who were neurologically intact. The presence of a neurological deficit is not an absolute contraindication for conservative treatment as supported by a high level of evidence. However, the majority of the literature excluded patients with neurological deficits. More evidence is needed to further classify the appropriate burst fractures for conservative management to decrease variables that may impact the prognosis.
authors: Department of Neurological Surgery, Northwestern University, Feinberg School of Medicine, Chicago, Illinois.
authors: Joshua
authors: J
authors: Bakhsheshian
authors: Nader S
authors: NS
authors: Dahdaleh
authors: Shayan
authors: S
authors: Fakurnejad
authors: Justin K
authors: JK
authors: Scheer
authors: Zachary A
authors: ZA
authors: Smith
mesh_terms: D019468:Disease Management; D019317:Evidence-Based Medicine; D006801:Humans; D039781:PubMed / Q000706:statistics & numerical data; D013119:Spinal Cord Injuries / Q000150:complications*; D016103:Spinal Fractures / Q000209:etiology* / Q000628:therapy*; D013904:Thoracic Vertebrae / Q000473:pathology
keywords: AO Type A3; ODI = Oswestry Disability Index; RCT = randomized controlled trial; RMDQ = Roland-Morris Disability Questionnaire; SF-36 = 36-Item Short-Form Health Survey; TLSO = thoracolumbar orthosis; VAS = visual analog scale; conservative management; nonoperative; orthosis; spine fracture; thoracolumbar burst fracture; trauma