title: The use of thermal techniques for the characterization and selection of natural biomaterials.
abstract: In this paper we explore the ability of thermal analysis to check elastin and collagen integrity in different biomaterial applications. Differential Scanning Calorimetry (DSC) has been used to analyze the first and second order transitions of the biological macromolecules in the hydrated and dehydrated state. First, we report the characterization of control cardiovascular tissues such as pericardium, aortic wall and valvular leaflet. Their thermal properties are compared to pure elastin and pure collagen. Second, we present results obtained on two collagen rich tissues: pericardia with different chemical treatments and collagen with physical treatments. Finally, more complex cardiovascular tissues composed of elastin and collagen are analyzed and the effect of detergent treatment on the physical structure of collagen and elastin is brought to the fore.
authors: Physique des Polymères, Institut Carnot CIRIMAT UMR5085, Université Paul Sabatier, 118 route de Narbonne, Bat 3R1B2, 31062 Toulouse Cedex, France. vsamou@cict.fr.
authors: Valérie
authors: V
authors: Samouillan
authors: Physique des Polymères, Institut Carnot CIRIMAT UMR5085, Université Paul Sabatier, 118 route de Narbonne, Bat 3R1B2, 31062 Toulouse Cedex, France.
authors: Florian
authors: F
authors: Delaunay
authors: Physique des Polymères, Institut Carnot CIRIMAT UMR5085, Université Paul Sabatier, 118 route de Narbonne, Bat 3R1B2, 31062 Toulouse Cedex, France.
authors: Jany
authors: J
authors: Dandurand
authors: LAPLACE, UMR CNRS 5213, Université Paul Sabatier, 118 Route de Narbonne, 31062 Toulouse Cedex 9, France.
authors: Nofel
authors: N
authors: Merbahi
authors: LAPLACE, UMR CNRS 5213, Université Paul Sabatier, 118 Route de Narbonne, 31062 Toulouse Cedex 9, France.
authors: Jean-Pierre
authors: JP
authors: Gardou
authors: LAPLACE, UMR CNRS 5213, Université Paul Sabatier, 118 Route de Narbonne, 31062 Toulouse Cedex 9, France.
authors: Mohammed
authors: M
authors: Yousfi
authors: Dipartimento di Scienze Biomediche Sperimentali, Università di Padova, Viale Colombo 3, 35131 Padova, Italy.
authors: Alessandro
authors: A
authors: Gandaglia
authors: Dipartimento di Scienze Biomediche Sperimentali, Università di Padova, Viale Colombo 3, 35131 Padova, Italy.
authors: Michel
authors: M
authors: Spina
authors: Physique des Polymères, Institut Carnot CIRIMAT UMR5085, Université Paul Sabatier, 118 route de Narbonne, Bat 3R1B2, 31062 Toulouse Cedex, France.
authors: Colette
authors: C
authors: Lacabanne