title: Two new Diels-Alder-type adducts from the stem barks of Morus yunanensis.
abstract: Two new Diels-Alder adducts, yunanensins B and D (1 and 2), were isolated from the stem bark of Morus yunanensis. Their structures were determined by spectroscopic analysis. Compounds 1 and 2 showed moderate antioxidant effects on liver microsomal lipid peroxidation induced by Fe(2+)-Cys system, with inhibitory ratios of 57.1% and 67.9% at a concentration of 10(-5) mol/l.
authors: a State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing 100050 , China.
authors: Jie
authors: J
authors: Kang
authors: Xi-Qiang
authors: XQ
authors: Cui
authors: Hong-Qing
authors: HQ
authors: Wang
authors: De-Quan
authors: DQ
authors: Yu
authors: Ruo-Yun
authors: RY
authors: Chen
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008315:Malondialdehyde / Q000032:analysis; D008862:Microsomes, Liver / Q000187:drug effects; D015394:Molecular Structure; D031625:Morus / Q000737:chemistry*; D024301:Plant Bark / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry
chemical_list: D000975:Antioxidants; D004365:Drugs, Chinese Herbal; D006576:Heterocyclic Compounds, 4 or More Rings; C000591875:yunanensin B; C000591876:yunanensin D; D008315:Malondialdehyde
keywords: Diels–Alder adducts; Morus yunanensis; antioxidant effects; yunanensins B and D