title: Copper-catalyzed synthesis of 1,1-diborylalkanes through regioselective dihydroboration of terminal alkynes.
abstract: The copper-catalyzed sequential hydroboration of terminal alkynes with pinacolborane to prepare 1,1-diborylalkanes directly from alkynes was studied. Protected propargyl amines, propargyl alcohol derivatives, and simple alkynes regioselectively produced the desired 1,1-diborylalkanes in good yields with a copper/xantphos catalyst.
authors: Department of Chemistry and Institute of Basic Science, Sungkyunkwan University, Suwon 440-746 (Korea), Fax: (+82) 31-290-7075.
authors: Sumin
authors: S
authors: Lee
authors: Dingxi
authors: D
authors: Li
authors: Jaesook
authors: J
authors: Yun
keywords: alkynes; copper; homogeneous catalysis; hydroboration; regioselectivity