title: Acinic cell carcinoma of minor salivary gland showing features of high-grade transformation.
abstract: BACKGROUND
  Acinic cell carcinoma (AciCC) of salivary gland is a relatively infrequent tumor. Though known for its low-grade behavior, its unpredictable element of recurrence and malignancy should never be ignored.
  
  
  METHODS
  A male patient with complaints of pain and swelling in the left jaw region since a year was operated based on the computed tomography (CT) and incisional biopsy report. Histopathology (routine staining, special staining, immunostaining and electron microscopy) of the excised specimen revealed it to be a variant of AciCC from minor salivary gland.
  
  
  CONCLUSIONS
  To the best of our knowledge, this is the first case of AciCC showing propensity for high-grade transformation (HGT), arising from minor salivary gland, being reported. The rarity of such variants and the importance of various investigative techniques in the diagnosis of such cases are discussed.
authors: Department of Oral and Maxillofacial Pathology, KSR Institute of Dental Science and Research, Tiruchengode, Namakkal, Tamil Nadu, India.
authors: Vadivel
authors: V
authors: Ilayaraja
authors: Department of Oral and Maxillofacial Pathology, KSR Institute of Dental Science and Research, Tiruchengode, Namakkal, Tamil Nadu, India.
authors: H
authors: H
authors: Prasad
authors: Department of Oral and Maxillofacial Pathology, KSR Institute of Dental Science and Research, Tiruchengode, Namakkal, Tamil Nadu, India.
authors: Krishnamurthy
authors: K
authors: Anuthama
authors: Department of Oral and Maxillofacial Pathology, KSR Institute of Dental Science and Research, Tiruchengode, Namakkal, Tamil Nadu, India.
authors: Ranganath
authors: R
authors: Sruthi
keywords: Acinic cell carcinoma; dedifferentiation; high-grade transformation; minor salivary gland