title: Effect of Er,Cr:YSGG laser irradiation with radial firing tips on Candida albicans in experimentally infected root canals.
abstract: OBJECTIVE
  To compare the disinfection effect of Er,Cr:YSGG laser using radial firing tips with NaOCI in root canals infected with C. albicans and to evaluate the irradiation effect on the dentinal surfaces.
  
  
  METHODS
  In total seventy-six mandibular premolar teeth were used. In order to standardize the incubation and sterilization procedure, eight teeth were used. Sixty-eight of the root canals were incubated with C. albicans suspension for 72 hours. The specimens were divided into 5 experimental groups. Two groups were constituted as Group 1 was irradiated with 1.5 W laser (n = 8) and group 2, which was irradiated with 2 W laser (n = 8). Two more groups were formed as Group 3 (2 W laser (n = 25) and Group 4 NaOCI (5%) (n = 25). Group 5 (n = 2) did not receive any treatment. Mann-Whitney U and Kruskal-Wallis H tests were used to compare the different laser output powers. Wilcoxon Signed Ranks Test was used in order to compare the Candida cfu/ml levels according to treatment protocols (P < 0.05).
  
  
  RESULTS
  Both 1.5 W and 2 W laser resulted in a major reduction of C. albicans without a significant difference. The comparison of the dentin surfaces irradiated with Er,Cr:YSGG laser at two power settings resulted in similar morphological changes. However, NaOCI was found to be more effective in reduction of C. albicans than 2 W laser application.
  
  
  CONCLUSIONS
  According to the results of the present study, the Er,Cr:YSGG laser with radial firing tips presented less antifungal effects on C. albicans in root canals of infected teeth than NaOCl solution.
authors: Department of Pediatric Dentistry, Faculty of Dentistry, Near East University, Nicosia, Northern Cyprus, Mersin 10, Turkey.
authors: Leman
authors: 0000-0001-8498-3742
authors: L
authors: Ozkan
authors: Department of Pediatric Dentistry, Faculty of Dentistry, Near East University, Nicosia, Northern Cyprus, Mersin 10, Turkey.
authors: Serap
authors: 0000-0003-1793-1840
authors: S
authors: Cetiner
authors: Department of Medical Microbiology, Celal Bayar University, Faculty of Medicine, 45000 Manisa, Turkey.
authors: Tamer
authors: 0000-0002-6015-8032
authors: T
authors: Sanlidag
mesh_terms: D000935:Antifungal Agents / Q000008:administration & dosage; D002176:Candida albicans / Q000187:drug effects* / Q000472:pathogenicity / Q000528:radiation effects*; D003786:Dental Pulp Cavity / Q000187:drug effects* / Q000382:microbiology / Q000528:radiation effects; D006801:Humans; D053685:Laser Therapy; D007834:Lasers; D014070:Tooth / Q000382:microbiology
chemical_list: D000935:Antifungal Agents