title: Treatment outcome in substance use disorder patients with and without comorbid posttraumatic stress disorder: A systematic review.
abstract: We investigated the role of comorbid posttraumatic stress disorder (CO-PTSD) in substance use disorder (DSM-IV/ICD-10 substance abuse or dependence, SUD) treatment. We conducted a systematic review of treatment outcome studies in SUD patients with and without CO-PTSD from 2000 to 2011. The N = 22 studies found differed clearly with regard to methodology and the sufficiency of provided study information, limiting their comparability. Remarkably, no consistent indication of a negative effect of CO-PTSD on the reported SUD treatment outcome was found. In addition to CO-PTSD, we point out possible further effect modifiers which need to be better understood. Finally, we emphasize the requirements for future research such as methodological standardization and a focus on long-term studies.
authors: a Institute of Psychology, University of Erlangen-Nuremberg , Erlangen , Germany.
authors: Anja
authors: A
authors: Hildebrand
authors: Silke
authors: S
authors: Behrendt
authors: Jürgen
authors: J
authors: Hoyer
mesh_terms: D015897:Comorbidity; D006801:Humans; D011613:Psychotherapy / Q000379:methods*; D013313:Stress Disorders, Post-Traumatic / Q000628:therapy*; D019966:Substance-Related Disorders / Q000628:therapy*; D016896:Treatment Outcome
keywords: comorbidity; outcome research; substance abuse; substance use disorder; trauma