title: Safety evaluation of Simarouba glauca seed fat.
abstract: Simarouba glauca DC is a tree of the family Simaroubaceae, which grows well up to 1,000 m above sea level in all types of well-drained soils (pH 5.5 to 8.0) and in places with 250 to 2,500 mm annual rainfall. The seed oil has been extracted both by mechanical expelling and solvent extraction. The fatty acid composition and iodine value of the oil indicate that it possesses saturated (40.8-42.6%), monounsaturated (52.9-55.0%), and polyunsaturated (2.5-3.4%) fatty acid in ratios close to that of palm oil. These characteristics are suitable for its use as edible oil. Acute oral toxicity and safety evaluation in a 13-week feeding trial on albino rats showed that the oil is comparable to groundnut oil in all the parameters.
authors: CSIR- Central Institute of Medicinal and Aromatic Plants, Lucknow-226 015, Uttar Pradesh, India.
authors: P K
authors: PK
authors: Rout
authors: Flat No.404, Adityahridayam, 55 Expressway, Kondapur, Hyderabad, 500084 India.
authors: Y R
authors: YR
authors: Rao
authors: CSIR- Regional Research Laboratory, Bhubaneshwar-751 013, Orissa, India.
authors: K S
authors: KS
authors: Jena
authors: CSIR- Central Institute of Medicinal and Aromatic Plants, Lucknow-226 015, Uttar Pradesh, India.
authors: D
authors: D
authors: Sahoo
authors: Biochemistry Department, Hamdard University, New Delhi, 110044 India.
authors: Shakir
authors: S
authors: Ali
keywords: Acute oral toxicity; Fatty acid; GC/MS; Refined simarouba oil; Simarouba glauca; Simaroubaceae