title: The normal internal carotid artery: a computed tomography angiographic study.
abstract: BACKGROUND
  Systematic computed tomography angiographic (CTA) studies investigating variation in internal carotid artery (ICA) luminal diameters (LDs) are scarce. Knowledge of the normal intra-individual LD variability would provide a cut-off value for detection of more subtle collapses. In addition, low intra-individual variability would allow using contralateral LD as a reference for estimation of stenosis degree in cases where ipsilateral measurement is hampered. Therefore, our aim was to investigate intra-individual LD variation of normal ICA.
  
  
  METHODS
  We retrospectively collected multidetector high-speed CTAs of 104 patients younger than 40 years who were considered not to have carotid pathology. We carried out independent measurements of the common carotid artery (CCA) and ICA LDs bilaterally from axial source images by two observers, analysing side-to-side LD differences from averaged double measurements with a paired t test.
  
  
  RESULTS
  We discovered no significant side-to-side LD differences. In the female group, the mean differences (mm) with 95% confidence intervals were 0.08 (0.00, 0.17) for CCA and 0.03 (-0.04, 0.11) for ICA, with ICA LD standard deviation of 0.4 mm. In the male group, these were: 0.06 (-0.04, 0.17), 0.02 (-0.07, 0.11) and 0.4 mm, respectively. We detected no ICA agenesis.
  
  
  CONCLUSIONS
  The intrinsic intra-individual variation of the LD of normal ICA is minimal. This uniformity may serve as the basis for detection of subtle grades of side-to-side variation caused by pathology.
authors: Department of Radiology, HUS Medical Imaging Center, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland, suvi.koskinen@iki.fi.
authors: Suvi Maaria
authors: SM
authors: Koskinen
authors: Lauri
authors: L
authors: Soinne
authors: Leena
authors: L
authors: Valanne
authors: Heli
authors: H
authors: Silvennoinen
mesh_terms: D000293:Adolescent; D000328:Adult; D000792:Angiography / Q000379:methods; D002343:Carotid Artery, Internal / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D008297:Male; D012016:Reference Values; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D055815:Young Adult