title: Vitamin D supplementation ameliorates hypoinsulinemia and hyperglycemia in static magnetic field-exposed rat.
abstract: The purpose of this study is to evaluate the effects of vitamin D supplementation on glucose and lipid metabolism in static magnetic field (SMF)-exposed rats. Rats exposed to SMF (128 mT; 1 h/day) during 5 consecutive days showed an increase in plasma glucose level and a decrease in plasma insulin concentration. By contrast, the same treatment failed to alter body weight and plasmatic total cholesterol, high-density lipoprotein (HDL)-cholesterol, low-density lipoprotein (LDL)-cholesterol, and triglyceride levels. Interestingly, supplementation with vitamin D (1,600 IU/100 g, per os) corrected and restored glycemia and insulinemia in SMF-exposed rats. The same treatment had no effects on lipid metabolism.
authors: a Laboratory of Integrative Physiology, Faculty of Sciences of Bizerte, Cathage University , Jarzouna , Tunisia.
authors: Aïda
authors: A
authors: Lahbib
authors: Soumaya
authors: S
authors: Ghodbane
authors: Karima
authors: K
authors: Maâroufi
authors: Karim
authors: K
authors: Louchami
authors: Abdullah
authors: A
authors: Sener
authors: Mohsen
authors: M
authors: Sakly
authors: Hafedh
authors: H
authors: Abdelmelek
mesh_terms: D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy* / Q000209:etiology; D019587:Dietary Supplements / Q000032:analysis; D005947:Glucose / Q000378:metabolism*; D006943:Hyperglycemia / Q000188:drug therapy* / Q000209:etiology; D050356:Lipid Metabolism / Q000528:radiation effects*; D060526:Magnetic Fields; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D014807:Vitamin D / Q000008:administration & dosage / Q000627:therapeutic use*; D014815:Vitamins / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D014815:Vitamins; D014807:Vitamin D; D005947:Glucose
keywords: SMF; glycemia; insulinemia; lipid metabolism; vitamin D supplementation