title: Excision alone for small size ductal carcinoma in situ of the breast.
abstract: This study was performed to determine the risk of tumor recurrence after local excision alone in patients with small size (≤1 cm) ductal carcinoma in situ (DCIS) of the breast. We have treated 107 patients who had DCIS measuring ≤1 cm with margin widths of ≥0.3 cm with excision alone per institutional protocol. With a median follow-up time of 58 months, 4 patients developed ipsilateral breast tumor recurrence (IBTR). Two of the 4 recurrences were invasive, whereas 2 were DCIS. The 5-year rate of IBTR was 6.1%. The patients with resection margin of <1.0 cm had significantly higher rate of IBTR than the patients with resection margin of ≥1.0 cm (23.1% vs. 1.5% at 5-year, p < 0.01). In conclusion, radiotherapy is necessary in the patients with resection margin of <1.0 cm after excision alone because of the substantial risk of IBTR.
authors: Department of Radiation Oncology, Hallym University Dongtan Sacred Heart Hospital, South Korea.
authors: Haeyoung
authors: H
authors: Kim
authors: Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Gangnam-gu, Seoul 135-710, South Korea.
authors: Jae Myoung
authors: JM
authors: Noh
authors: Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Gangnam-gu, Seoul 135-710, South Korea. Electronic address: doho.choi@samsung.com.
authors: Doo Ho
authors: DH
authors: Choi
authors: Department of Radiation Oncology, Ewha Womans University Medical Center, South Korea.
authors: Jihye
authors: J
authors: Lee
authors: Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, South Korea.
authors: Seok Jin
authors: SJ
authors: Nam
authors: Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, South Korea.
authors: Jeong Eon
authors: JE
authors: Lee
authors: Department of Radiation Oncology, Ewha Womans University Medical Center, South Korea.
authors: Won
authors: W
authors: Park
authors: Department of Radiation Oncology, Ewha Womans University Medical Center, South Korea.
authors: Seung Jae
authors: SJ
authors: Huh
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology / Q000517:prevention & control*; D012189:Retrospective Studies; D016896:Treatment Outcome; D047368:Tumor Burden
keywords: Breast; Intraductal carcinoma; Radiotherapy; Surgery