title: Coexisting glomerular IgA deposition and IgG-kappa multiple myeloma.
abstract: Multiple myeloma (MM) is a common malignancy that often results in many kinds of kidney injuries for the abnormal monoclonal immunoglobulin. Here, we present an IgG-kappa type MM case accompanied by renal IgA deposition combined with IgG-kappa. The patient was treated with prednisone plus mycophenolate mofetil, and got a satisfactory remission. Although it cannot be determined whether the IgA deposition was secondary to MM, this was the first report of coexisting mesangial proliferative nephritis with IgA deposition and IgG-kappa type MM.
authors: Department of Nephrology and Rheumatology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital , Shanghai , China and.
authors: Feng
authors: F
authors: Wang
authors: Tao
authors: T
authors: Xing
authors: Junhui
authors: J
authors: Li
authors: Zhi-Gang
authors: ZG
authors: Zhang
authors: Niansong
authors: N
authors: Wang
mesh_terms: D000368:Aged; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology* / Q000378:metabolism*; D007074:Immunoglobulin G / Q000276:immunology*; D007678:Kidney Glomerulus / Q000378:metabolism*; D008297:Male; D009101:Multiple Myeloma / Q000145:classification / Q000150:complications* / Q000276:immunology / Q000378:metabolism*; D009393:Nephritis / Q000145:classification / Q000150:complications* / Q000276:immunology / Q000378:metabolism*
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G
keywords: Immunoglobulin A; mesangial proliferative nephritis; multiple myeloma; proteinuria