title: A photoresponsive glycosidase mimic.
abstract: Azobenzene-3,3'-dicarboxylic acid exists in photoisomerizable (E) and (Z)-forms. Deprotonation of the carboxylic acid groups from the (E)-form occurs simultaneously, whereas in the (Z)-form it occurs in a stepwise fashion. The mono anionic form of the (Z)-isomer acts as a glycosidase mimic that proceeds through a general acid-general base catalytic mechanism. This is the first example of a photoresponsive glycosidase mimic.
authors: Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur, WB 741246, India. sb1@iiserkol.ac.in.
authors: Mousumi
authors: M
authors: Samanta
authors: V
authors: V
authors: Siva Rama Krishna
authors: Subhajit
authors: S
authors: Bandyopadhyay
mesh_terms: D001391:Azo Compounds / Q000737:chemistry; D001672:Biocompatible Materials / Q000737:chemistry* / Q000378:metabolism; D002384:Catalysis; D003998:Dicarboxylic Acids / Q000737:chemistry; D006026:Glycoside Hydrolases / Q000737:chemistry / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008027:Light; D013237:Stereoisomerism; D013696:Temperature; D014466:Ultraviolet Rays
chemical_list: D001391:Azo Compounds; D001672:Biocompatible Materials; D003998:Dicarboxylic Acids; D006026:Glycoside Hydrolases; C009850:azobenzene