title: Ménétrier's disease, a premalignant condition, with coexisting advanced gastric cancer: A case report and review of the literature.
abstract: Ménétrier's disease (MD) is a rare type of hypertrophic gastropathy involving the body of the stomach, which is characterized by thickening of the mucous membrane in the form of giant rugal folds, hypochlorhydria and protein loss. The potential for malignant transformation of this lesion remains a controversial topic. Therefore, in the present study, a case of a 51-year-old male exhibiting MD with coexisting advanced gastric cancer is described; a review of the literature is also presented. The present case emphasized that MD requires particular attention and should be regarded as a premalignant condition due to the previously documented cases of its coexistence with gastric cancer, in addition to the lack of knowledge regarding its pathogenesis and effective therapeutic management.
authors: Department of General Pathomorphology, The Medical University of Białystok, Białystok 15-269, Poland.
authors: Anna
authors: A
authors: Pryczynicz
authors: The Second Department of General and Gastroenterological Surgery, The Medical University of Białystok, Białystok 15-269, Poland.
authors: Roman
authors: R
authors: Bandurski
authors: Department of General Pathomorphology, The Medical University of Białystok, Białystok 15-269, Poland.
authors: Katarzyna
authors: K
authors: Guzińska-Ustymowicz
authors: Department of General Pathomorphology, The Medical University of Białystok, Białystok 15-269, Poland.
authors: Katarzyna
authors: K
authors: Niewiarowska
authors: Department of General Pathomorphology, The Medical University of Białystok, Białystok 15-269, Poland.
authors: Andrzej
authors: A
authors: Kemona
authors: The Second Department of General and Gastroenterological Surgery, The Medical University of Białystok, Białystok 15-269, Poland.
authors: Bogusław
authors: B
authors: Kędra
keywords: Ménétrier’s disease; adenocarcinoma; gastric cancer