title: Brief report: assessment of early sensory processing in infants at high-risk of autism spectrum disorder.
abstract: This study assessed sensory processing differences between 24-month infants at high-risk of autism spectrum disorder (ASD), each with an older sibling with ASD, and low-risk infants with no family history of ASD. Sensory processing differences were assessed using the Infant/Toddler Sensory Profile, a parent-reported measure. Groups were compared based on 3-year outcomes: (a) high-risk infants subsequently diagnosed with ASD; (b) high-risk infants without an ASD diagnosis; and (c) low-risk infants without an ASD diagnosis. Analyses showed that high-risk infants diagnosed with ASD have more difficulty with auditory processing (i.e., responses to auditory stimuli) and lower registration (i.e., lacking sensation awareness) compared to controls. Thus, behavioral responses to sensory input represent early risk markers of ASD, particularly in high-risk infants.
authors: Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada, germani@ualberta.ca.
authors: Tamara
authors: T
authors: Germani
authors: Lonnie
authors: L
authors: Zwaigenbaum
authors: Susan
authors: S
authors: Bryson
authors: Jessica
authors: J
authors: Brian
authors: Isabel
authors: I
authors: Smith
authors: Wendy
authors: W
authors: Roberts
authors: Peter
authors: P
authors: Szatmari
authors: Caroline
authors: C
authors: Roncadin
authors: Lori Ann R
authors: LA
authors: Sacrey
authors: Nancy
authors: N
authors: Garon
authors: Tracy
authors: T
authors: Vaillancourt
mesh_terms: D002659:Child Development Disorders, Pervasive / Q000175:diagnosis* / Q000523:psychology; D002675:Child, Preschool; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D007223:Infant; D008137:Longitudinal Studies; D008297:Male; D011446:Prospective Studies; D058028:Research Report; D012307:Risk Factors; D012677:Sensation / Q000502:physiology*; D012678:Sensation Disorders / Q000175:diagnosis* / Q000523:psychology