title: An interesting case of cryptogenic stroke in a young man due to left ventricular non-compaction: role of cardiac MRI in the accurate diagnosis.
abstract: A 28-year-old man arrived for an outpatient cardiac MRI (CMR) study to evaluate cardiac structure. At the age of 24 the patient presented with acute onset expressive aphasia and was diagnosed with ischaemic stroke. Echocardiography at that time was reported as 'apical wall thickening consistent with apical hypertrophic cardiomyopathy'. CMR revealed a moderately dilated left ventricle with abnormal appearance of the left ventricular (LV) apical segments. Further evaluation was consistent with a diagnosis of LV non-compaction (LVNC) cardiomyopathy with a ratio of non-compacted to compacted myocardium measuring 3. There was extensive delayed hyperenhancement signal involving multiple segments representing a significant myocardial scar which is shown to have a prognostic role. Our patient, with no significant cerebrovascular risk factors, would likely have had an embolic stroke. This case demonstrates the role of CMR in accurately diagnosing LVNC in a patient with young stroke where prior echocardiography was non-diagnostic.
authors: Department of Inpatient Medicine, University of Arizona, Tucson, Arizona, USA.
authors: Arun
authors: A
authors: Kannan
authors: Department of Inpatient Medicine, University of Arizona, Tucson, Arizona, USA.
authors: Anindita
authors: A
authors: Das
authors: Department of Cardiology, Sarver Heart Center, Tucson, Arizona, USA.
authors: Rajesh
authors: R
authors: Janardhanan
mesh_terms: D000328:Adult; D002545:Brain Ischemia / Q000209:etiology*; D006801:Humans; D056830:Isolated Noncompaction of the Ventricular Myocardium / Q000150:complications* / Q000175:diagnosis; D018810:Magnetic Resonance Angiography; D008297:Male; D020521:Stroke / Q000209:etiology*