title: Atlantinone A, a Meroterpenoid Produced by Penicillium ribeum and Several Cheese Associated Penicillium Species.
abstract: Atlantinone A has been isolated from the psychrotolerant fungus Penicillium ribeum. The exact structure of the compound was confirmed by mass spectrometric and 1- and 2D NMR experiments. Atlantinone A was originally only produced upon chemical epigenetic manipulation of P. hirayamae, however in this study the compound was found to be produced at standard growth conditions by the following species; P. solitum, P. discolor, P. commune, P. caseifulvum, P. palitans, P. novae-zeelandiae and P. monticola. A biosynthetic pathway to atlantinone A starting from andrastin A is proposed.
authors: Department of Forensic Medicine, University of Copenhagen, Frederik V's Vej 11, DK-2100 Copenhagen, Denmark.
authors: Petur W
authors: PW
authors: Dalsgaard
authors: Carlsberg Laboratory, Gamle Carlsbergvej 10, DK-2500 Valby, Denmark.
authors: Bent O
authors: BO
authors: Petersen
authors: Munkehøjvænge 31, 3520 Farum, Denmark.
authors: Jens Ø
authors: JØ
authors: Duus
authors: Institut für Pharmazie, Leopold-Franzens-Universität, Innrain 52, A-6020 Innsbruck, Austria.
authors: Christian
authors: C
authors: Zidorn
authors: Center for Microbial Biotechnology, DTU Systems Biology, Building 221, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark.
authors: Jens C
authors: JC
authors: Frisvad
authors: Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark.
authors: Carsten
authors: C
authors: Christophersen
authors: Center for Microbial Biotechnology, DTU Systems Biology, Building 221, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark. tol@bio.dtu.dk.
authors: Thomas O
authors: TO
authors: Larsen