title: C-21 steroidal glycosides from Dregea sinensis.
abstract: Two new C-21 steroidal glycosides, dregeosides D (1) and E (2), were isolated from the roots of Dregea sinensis. The structures of the isolated compounds were elucidated on the basis of 1D and 2D NMR spectra and HR-ESI-MS analysis. Finally, the inhibited effects of the isolated compounds on interleukin 2 receptor were evaluated by enzyme-linked immunosorbent assay.
authors: a School of Life Science, Beijing Institute of Technology , Beijing 100081 , China.
authors: Shao-Hua
authors: SH
authors: Jia
authors: Fang
authors: F
authors: Lv
authors: Rong-Ji
authors: RJ
authors: Dai
authors: Wei-Wei
authors: WW
authors: Meng
authors: Yan
authors: Y
authors: Chen
authors: Yu-Lin
authors: YL
authors: Deng
mesh_terms: D029062:Apocynaceae / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008519:Medicine, Traditional; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D015375:Receptors, Interleukin-2 / Q000187:drug effects; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D004365:Drugs, Chinese Herbal; D006027:Glycosides; D015375:Receptors, Interleukin-2; D013256:Steroids; C000592716:dregeoside D; C000592717:dregeoside E
keywords: Asclepiadaceae; Dregea sinensis; interleukin 2 receptor; steroidal glycosides