title: [Study on the chemical constituents from the roots of Ligularia dentata in Henan].
abstract: OBJECTIVE
  To study the chemical constituents from the roots of Ligularia dentata in Henna.
  
  
  METHODS
  Chemical constituents from the roots of Ligularia dentata in Henan were isolated and purified by silica gel, Sephadex LH-20 column chromatography and solvent crystallization and their structures were identified by spectral methods.
  
  
  RESULTS
  Four eremophilane-type sesquiterpenoids were obtained and determined as 3-oxo-8alpha-hydroxy-10alphaH-eremophilan-1,7-dien-8, 12beta-olide(1), 3-oxo-eremophil-1, 7-dien-8, 12beta-olide (2),3-oxo-8alpha-ethoxy-10alphaH-eremophil-1,7-dien-8,12-olide(3) and furanoligularenone(4).
  
  
  CONCLUSIONS
  Compound 1-4 are isolated from this plant for the first time and their contents in the roots are high by HPLC analysis except for compound 3. Compound 3 is hardly detected in the fresh EtOH extract and might be derived from other compounds during the extraction.
authors: Shuang
authors: S
authors: Li
authors: Ru
authors: R
authors: Yang
authors: Xian-lei
authors: XL
authors: Zeng
authors: Cai-fang
authors: CF
authors: Wang
mesh_terms: D019659:Asteraceae / Q000737:chemistry*; D002681:China; D002851:Chromatography, High Pressure Liquid; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D012717:Sesquiterpenes; C455061:furanoligularenone