title: Effectiveness evaluation of a pharmacist-driven monitoring database for tardive dyskinesia.
abstract: BACKGROUND
  Tardive dyskinesia (TD) is a potentially irreversible, chronic syndrome related to antipsychotic medication use characterized by hyperkinetic abnormal involuntary movements. Various studies have shown that development of TD is possible with both first- and second-generation antipsychotics. Regular monitoring for emergence of TD symptoms is recommended in clinical practice for early recognition and intervention.
  
  
  METHODS
  This is a retrospective, single-center, observational study of the effectiveness of a pharmacist-driven monitoring database for TD assessment. Subjects were adult inpatients at a state psychiatric hospital who received antipsychotic treatment for at least 3 or 6 months between January 2006 and December 2011. The primary objective was to assess compliance rates with TD monitoring based on facility policy before and after implementation of the database at 3 and 6 months following initiation of antipsychotic therapy.
  
  
  RESULTS
  A significant improvement in compliance with TD monitoring policy was seen after implementation of the database (2.9% vs 66.7%; P < .001). Compliance with TD monitoring did not differ between classes of antipsychotic medication, hospital units, or age groups.
  
  
  CONCLUSIONS
  The results of this study demonstrate that pharmacists can help improve compliance with TD assessment and that monitoring databases may be useful for similar extended or long-term care settings to ensure timely assessment of patients for the development or progression of TD.
authors: Center for Behavioral Medicine, Department of Pharmacy , Kansas City, Missouri.
authors: Lauren A
authors: LA
authors: Diefenderfer
authors: Center for Behavioral Medicine, Department of Pharmacy , Kansas City, Missouri ; University of Missouri-Kansas City School of Pharmacy, Division of Pharmacy Practice and Administration , Kansas City, Missouri.
authors: Leigh Anne
authors: LA
authors: Nelson
authors: Center for Behavioral Medicine, Department of Pharmacy , Kansas City, Missouri.
authors: Ellie
authors: E
authors: Elliott
authors: University of Missouri-Kansas City School of Pharmacy, Division of Pharmacy Practice and Administration , Kansas City, Missouri.
authors: Yifei
authors: Y
authors: Liu
authors: Center for Behavioral Medicine, Department of Pharmacy , Kansas City, Missouri.
authors: Courtney
authors: C
authors: Iuppa
authors: University of Missouri-Kansas City School of Pharmacy, Division of Pharmacy Practice and Administration , Kansas City, Missouri.
authors: Elizabeth
authors: E
authors: Winans
authors: Center for Behavioral Medicine, Department of Pharmacy , Kansas City, Missouri ; University of Missouri-Kansas City School of Pharmacy, Division of Pharmacy Practice and Administration , Kansas City, Missouri.
authors: Roger W
authors: RW
authors: Sommi
keywords: antipsychotics; monitoring; tardive dyskinesia