title: Pure in-phase heteronuclear correlation NMR experiments.
abstract: A general NMR approach to provide pure in-phase (PIP) multiplets in heteronuclear correlation experiments is described. The implementation of a zero-quantum filter efficiently suppresses any unwanted anti-phase contributions that usually distort the multiplet pattern of cross-peaks and can hamper their analysis. The clean pattern obtained in PIP-HSQMBC experiments is suitable for a direct extraction of coupling constants in resolved signals, for a peak-fitting process from a reference signal, and for the application of the IPAP technique in non-resolved multiplets.
authors: Servei de RMN and Departament de Química, Universitat Autònoma de Barcelona, 08193 Bellaterra (Spain).
authors: Laura
authors: L
authors: Castañar
authors: Josep
authors: J
authors: Saurí
authors: Robert Thomas
authors: RT
authors: Williamson
authors: Albert
authors: A
authors: Virgili
authors: Teodor
authors: T
authors: Parella
mesh_terms: D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D019906:Nuclear Magnetic Resonance, Biomolecular; D011522:Protons; D012815:Signal Processing, Computer-Assisted; D013331:Strychnine / Q000737:chemistry*
chemical_list: D011522:Protons; D013331:Strychnine
keywords: HSQC; HSQMBC; coupling constants; heteronuclear long-range correlation; pure in-phase NMR