title: Impact of night sleep duration on glycemic and triglyceride levels in Chinese with different glycemic status.
abstract: BACKGROUND
  The aim of the present study was to assess the relationship between night sleep duration and glycemic and triglyceride (TG) levels among people with different glycemic status.
  
  
  METHODS
  In all, 18,121 subjects aged ≥40 years were enrolled in this cross-sectional study, including 4318 with impaired glucose regulation (IGR), 4225 with diabetes, and 9578 with normal glucose regulation (NGR). The IGR + diabetes and NGR groups were divided into three subgroups according to self-reported night sleep duration as follows: (i) <6 h; (ii) 6-9 h; and (iii) >9 h. The associations of sleep duration with HbA1c, fasting plasma glucose (FPG), 2-h post-load plasma glucose (PPG), and TG levels were examined.
  
  
  RESULTS
  Long night sleep duration (>9 h) was associated with higher HbA1c, FPG, PPG, and TG levels compared with sleep duration of 6-9 h (P < 0.01 for all) in the IGR + diabetes group, but not in the NGR group. This association was adjusted for potential confounders, including body mass index and depressive symptoms, and remained significant even after adjusting for snoring. A significant interaction between sleep duration and TG or snoring was observed for HbA1c levels, which attenuated the sleep-HbA1c association in the IGR + diabetes group. However, no significant association was observed between short night sleep duration and HbA1c levels.
  
  
  CONCLUSIONS
  Long night sleep duration is associated with higher HbA1c, FPG, PPG, and TG levels in IGR and diabetes patients, independent of potential confounders. This may be important in clinical management of IGR and diabetes patients.
authors: Department of Endocrinology, Chinese PLA General Hospital, Beijing, China; School of Medicine, Nankai University, Tianjin, China.
authors: Yu
authors: Y
authors: Zheng
authors: Anping
authors: A
authors: Wang
authors: Changyu
authors: C
authors: Pan
authors: Juming
authors: J
authors: Lu
authors: Jingtao
authors: J
authors: Dou
authors: Zhaohui
authors: Z
authors: Lu
authors: Jianming
authors: J
authors: Ba
authors: Baoan
authors: B
authors: Wang
authors: Yiming
authors: Y
authors: Mu
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis*; D015992:Body Mass Index; D016022:Case-Control Studies; D002681:China; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology*; D005215:Fasting / Q000502:physiology; D005260:Female; D005951:Glucose Tolerance Test; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D007333:Insulin Resistance; D008297:Male; D008875:Middle Aged; D011236:Prediabetic State / Q000503:physiopathology*; D012890:Sleep / Q000502:physiology*; D013997:Time Factors; D014280:Triglycerides / Q000032:analysis*
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; D014280:Triglycerides
keywords: glycemic control; prevalence; sleep duration; type 2 diabetes; 关键词：血糖控制，患病率，睡眠时间、2型糖尿病