title: Regulatory T cells and cancer: an undesired tolerance.
abstract: The incidence of cancer is markedly increased in organ transplant patients. A better understanding of underlying mechanisms and the identification of biomarkers for diagnosis and prognosis are major challenges. Hope et al. report expansion of regulatory T cells to be associated with the presence and severity of cancer. Although relevant, these results raise several questions.
authors: 1] Unité Mixte de Recherche INSERM 1098, Fédération Hospitalo-Universitaire INCREASE, Besançon, France [2] Université de Franche-Comté Institut Fédératif de Recherche 133, Besançon, France [3] Centre Hospitalier Universitaire, Besançon, France [4] Centre d'Investigation Clinique en Biothérapies 506, Besançon, France.
authors: Didier
authors: D
authors: Ducloux
mesh_terms: D005260:Female; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D009369:Neoplasms / Q000209:etiology* / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*