title: Sox4 B-lymphocyte progenitors.
abstract: In this issue of Blood, Mallampati et al provide mechanistic insight into the functions of the transcription factor Sox4 in pro-B lymphocytes using both gain-of-function and loss-of-function approaches combined with global gene expression and genome-wide transcription factor binding analysis.
authors: THE UNIVERSITY OF CHICAGO.
authors: Barbara L
authors: BL
authors: Kee
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000378:metabolism*; D048149:Casein Kinase 1 epsilon / Q000096:biosynthesis*; D002454:Cell Differentiation / Q000502:physiology*; D004268:DNA-Binding Proteins / Q000378:metabolism*; D015971:Gene Expression Regulation, Enzymologic / Q000502:physiology*; D018398:Homeodomain Proteins / Q000378:metabolism*; D055751:SOXC Transcription Factors / Q000378:metabolism*
chemical_list: D004268:DNA-Binding Proteins; D018398:Homeodomain Proteins; C499308:Rag2 protein, mouse; D055751:SOXC Transcription Factors; C489990:Sox4 protein, mouse; C064658:RAG-1 protein; D048149:Casein Kinase 1 epsilon