title: [Differences in the survival after an episode of stroke treated with thrombolytic therapy. Study Ebrictus].
abstract: OBJECTIVE
  To seek if there is gender survival difference among patients treated with thrombolytic therapy.
  
  
  METHODS
  Cohort study.
  
  
  METHODS
  Community based register.
  
  
  METHODS
  91 subjects with an episode of stroke collected since April 2006 up to September 2013 and treated with thrombolytic therapy.
  
  
  METHODS
  Monitoring of vital status.
  
  
  METHODS
  We collected baseline characteristics in Framingham, Regicor, CHA2DS2-VASc, Essen, NIHSS, Barthel scales and outcomes according to gender; person-time incidence rate; survival analysis by Kaplan-Meier's curves, bivariate analysis between survivors and deaths, and Cox multivariate.
  
  
  RESULTS
  91 patients with middle age 68.02±11.9 years. The men have higher cardiovascular basal risk. The average time of follow-up was 2.95±2.33 years. Incidence rate ratio (IR) shown higher risk in men than in women IR=3.2 (CI 95% 1.2-8.0). The dead cases were older (P=.032); with higher cardiovascular basal risk (P=.040) and more risk of stroke recurrence (P=<.001), with cardiovascular pathology before the stroke (P=.005); more stroke severity (P=.002); and a major fall in the score Barthel one year after the episode (P=.016). The percentage of deaths is significantly higher when the patient is referred by complications to other centres (P=.006) in relation to those referred to home, but just the gender (HR: 1,12; IC 95%: 1,05-1,20) and secondary cardiovascular prevention (HR: 0,13; IC 95%: 0,06-0,28) were associated with higher risk of mortality.
  
  
  CONCLUSIONS
  After stroke episode treated with thrombolytic therapy, men have 12% higher risk of dying than women and don't be treated with secondary cardiovascular prevention rise 7.7 times the mortality risk.
authors: EAP Tortosa 1-est, Unidad Docente Tortosa, SAP Terres de l'Ebre, Institut Català Salut, Generalitat Catalunya, Tortosa, España. Electronic address: jlclua@telefonica.net.
authors: Jose Luis
authors: JL
authors: Clua-Espuny
authors: EAP Tortosa 1-est, Unidad Docente Tortosa, SAP Terres de l'Ebre, Institut Català Salut, Generalitat Catalunya, Tortosa, España.
authors: Rosa
authors: R
authors: Ripolles-Vicente
authors: Àrea de Biología Molecular i Recerca, Hospital de Tortosa Verge de la Cinta, IDIAP, IISPV y URV, Tortosa, Tarragona, España.
authors: Carlos
authors: C
authors: Lopez-Pablo
authors: EAP Aldea-Camarles-Ampolla, SAP Terres de l'Ebre, Institut Català Salut, Generalitat Catalunya, Tortosa, España.
authors: Anna
authors: A
authors: Panisello-Tafalla
authors: EAP Deltebre, Unidad Docente Tortosa, SAP Terres de l'Ebre, Institut Català Salut, Generalitat Catalunya, Tortosa, España.
authors: Jorgina
authors: J
authors: Lucas-Noll
authors: EAP Tortosa 1-est, Unidad Docente Tortosa, SAP Terres de l'Ebre, Institut Català Salut, Generalitat Catalunya, Tortosa, España.
authors: Cristina
authors: C
authors: Calduch-Noll
authors: EAP Aldea-Camarles-Ampolla, SAP Terres de l'Ebre, Institut Català Salut, Generalitat Catalunya, Tortosa, España.
authors: M Antonia
authors: MA
authors: González-Henares
authors: EAP Aldea-Camarles-Ampolla, SAP Terres de l'Ebre, Institut Català Salut, Generalitat Catalunya, Tortosa, España.
authors: M Lluisa
authors: ML
authors: Queralt-Tomas
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017678:Sex Distribution; D020521:Stroke / Q000188:drug therapy* / Q000401:mortality*; D015996:Survival Rate; D015912:Thrombolytic Therapy
keywords: Atención primaria; Fibrinólisis; Gender; Género; Ictus; Primary care; Stroke; Supervivencia; Survival; Thrombolysis