title: Abnormal nail fold capillaroscopic findings in patients with coronary slow flow phenomenon.
abstract: The coronary slow flow phenomenon (CSFP) is the delayed opacification of coronary arteries in the absence of significant stenosis. The pathogenesis of CSFP has not been completely understood yet. There are several proposed mechanisms such as the structural and functional abnormalities in coronary microcirculation. Nail fold capillaroscopy is a simple, noninvasive examination of the microvasculature and suggested to be a useful technique for analysis in various inflammatory and autoimmune diseases. In this study; we hypothesized that; CSFP is a part of systemic vascular entity rather than a problem confined to coronary vasculature and our aim was to investigate the nail fold capillaries of the patients with CSFP and compare to those with normal coronary flow (NCF). The study was designed as a case-control study and total 25 patients (10 male, mean age 55 ± 9 years) with documented CSFP, and 24 patients (15 male, mean age 55 ± 11 years) with NCF were recruited. Nail fold capillaroscopy examinations were performed by video dermatoscopy in all patients and results were compared between two groups. The demographic and clinical characteristics were similar between patients of CSFP and NCF groups. Nail fold capillary abnormalities including dilatation, tortuosity and microhemorrhage were present in 15 (60%) patients in CSFP group and 5 (21%) patients in NCF group (p < 0.05 OR: 5.7 95% C.I 1.602-20.279). In this study, we found that the abnormalities in nail fold capillaries suggesting the presence of inflammation and anatomical changes were significantly higher in patients with CSFP.
authors: Department of Cardiology, Faculty of Medicine, Ondokuz Mayis University Samsun, Turkey.
authors: Serkan
authors: S
authors: Yuksel
authors: Department of Dermatology, Faculty of Medicine, Ondokuz Mayis University Samsun, Turkey.
authors: Esra
authors: E
authors: Pancar Yuksel
authors: Department of Cardiology, Faculty of Medicine, Ondokuz Mayis University Samsun, Turkey.
authors: Mustafa
authors: M
authors: Yenercag
authors: Department of Cardiology, Faculty of Medicine, Ondokuz Mayis University Samsun, Turkey.
authors: Korhan
authors: K
authors: Soylu
authors: Department of Cardiology, Faculty of Medicine, Ondokuz Mayis University Samsun, Turkey.
authors: Halit
authors: H
authors: Zengin
authors: Department of Cardiology, Faculty of Medicine, Ondokuz Mayis University Samsun, Turkey.
authors: Okan
authors: O
authors: Gulel
authors: Department of Cardiology, Faculty of Medicine, Ondokuz Mayis University Samsun, Turkey.
authors: Murat
authors: M
authors: Meriç
authors: Department of Dermatology, Faculty of Medicine, Ondokuz Mayis University Samsun, Turkey.
authors: Fatma
authors: F
authors: Aydin
authors: Department of Dermatology, Faculty of Medicine, Ondokuz Mayis University Samsun, Turkey.
authors: Nilgun
authors: N
authors: Senturk
authors: Department of Cardiology, Faculty of Medicine, Ondokuz Mayis University Samsun, Turkey.
authors: Mahmut
authors: M
authors: Sahin
keywords: Coronary slow flow phenomenon; capillaroscopy; coronary artery disease; inflammation; microvascular; nail fold capillary