title: A meta-analysis of surgical versus nonsurgical management of recurrent thymoma.
abstract: This meta-analysis was designed to determine the effect of surgical and nonsurgical approaches on 5-year and 10-year overall survival (OS) in patients with recurrent thymoma. PubMed, Scopus, and the Journal of Japanese Association for Chest Surgery were queried, and 11 studies were eligible. Our meta-analysis using a random-effect model revealed significant differences in the rates of 5- and 10-year OS after thymectomy and in 5-year OS after recurrence, favoring surgically managed patients. Surgical resection may be associated with improved long-term survival and should be considered for patients with recurrent thymoma.
authors: Department of Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan. Electronic address: mhamaji@kuhp.kyoto-u.ac.jp.
authors: Masatsugu
authors: M
authors: Hamaji
authors: Division of Cardiothoracic Surgery, Altru Hospital, Grand Forks, North Dakota.
authors: Syed Osman
authors: SO
authors: Ali
authors: Department of Cardiothoracic Surgery, Division of Thoracic Surgery, Stanford University Medical School, Stanford, California.
authors: Bryan M
authors: BM
authors: Burt
mesh_terms: D057189:Checklist; D006801:Humans; D015996:Survival Rate; D013934:Thymectomy; D013945:Thymoma / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D013953:Thymus Neoplasms / Q000401:mortality / Q000601:surgery / Q000628:therapy*