title: [PSA testing, biopsy and cancer and benign prostate hyperplasia in France].
abstract: BACKGROUND
  Prostate-specific antigen (PSA) testing is high in France. The aim of this study was to estimate their frequency and those of biopsy and newly diagnosed cancer (PCa) according to the presence or absence of treated benign prostatic hyperplasia (BPH).
  
  
  METHODS
  This study concerned men 40 years and older covered by the main French national health insurance scheme (73 % of all men of this age). Data were collected from the national health insurance information system (SNIIRAM). This database comprehensively records all of the outpatient prescriptions and healthcare services reimbursed. This information are linked to data collected during hospitalisations.
  
  
  RESULTS
  The frequency of men without diagnosed PCa (10.9 millions) with at least one PSA test was very high in 2011 (men aged 40 years and older: 30 %, 70-74 years: 56 %, 85 years and older: 33 % and without HBP: 25 %, 41 % and 19 %). Men with treated BPH totalized 9 % of the study population, but 18 % of the men with at least one PSA test, 44 % of those with at least one prostate biopsy and 40 % of those with newly managed PCa. Over a 3-year period, excluding men with PCa, 88 % of men with BPH had at least one PSA test and 52 % had three or more PSA tests versus 52 % and 15 % for men without BPH. One year after PSA testing, men of 55-69 years with BPH more frequently underwent prostate biopsy than those without BPH (5.4 % vs 1.8 %) and presented PCa (1.9 % vs 0.9 %).
  
  
  CONCLUSIONS
  PSA testing frequencies in France are very high even after exclusion of men with BPH, who can be a group with more frequent managed PCa.
  
  
  METHODS
  4.
authors: Caisse nationale d'assurance maladie des travailleurs salariés (CNAMTS), direction de la stratégie des études et des statistiques, 26-50, avenue du Professeur-André-Lemierre, 75986 Paris cedex 20, France. Electronic address: philippe.tuppin@cnamts.fr.
authors: P
authors: P
authors: Tuppin
authors: Caisse nationale d'assurance maladie des travailleurs salariés (CNAMTS), direction de la stratégie des études et des statistiques, 26-50, avenue du Professeur-André-Lemierre, 75986 Paris cedex 20, France.
authors: S
authors: S
authors: Samson
authors: Caisse nationale d'assurance maladie des travailleurs salariés (CNAMTS), direction de la stratégie des études et des statistiques, 26-50, avenue du Professeur-André-Lemierre, 75986 Paris cedex 20, France.
authors: A
authors: A
authors: Fagot-Campagna
authors: Service d'urologie, hôpital Tenon, Assistance publique-Hôpitaux de Paris, 75020 Paris, France.
authors: B
authors: B
authors: Lukacs
authors: Caisse nationale d'assurance maladie des travailleurs salariés (CNAMTS), direction de la stratégie des études et des statistiques, 26-50, avenue du Professeur-André-Lemierre, 75986 Paris cedex 20, France.
authors: F
authors: F
authors: Alla
authors: Caisse nationale d'assurance maladie des travailleurs salariés (CNAMTS), direction de la stratégie des études et des statistiques, 26-50, avenue du Professeur-André-Lemierre, 75986 Paris cedex 20, France.
authors: H
authors: H
authors: Allemand
authors: Membres du groupe de travail du conseil scientifique de la CNAMTS, 75986 Paris cedex 20, France.
authors: F
authors: F
authors: Paccaud
authors: Membres du groupe de travail du conseil scientifique de la CNAMTS, 75986 Paris cedex 20, France.
authors: J-C
authors: JC
authors: Thalabard
authors: Membres du groupe de travail du conseil scientifique de la CNAMTS, 75986 Paris cedex 20, France.
authors: E
authors: E
authors: Vicaut
authors: Membres du groupe de travail du conseil scientifique de la CNAMTS, 75986 Paris cedex 20, France.
authors: M
authors: M
authors: Vidaud
authors: Membres du groupe de travail du conseil scientifique de la CNAMTS, 75986 Paris cedex 20, France.
authors: B
authors: B
authors: Millat
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D005602:France; D006801:Humans; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood*; D011470:Prostatic Hyperplasia / Q000150:complications; D011471:Prostatic Neoplasms / Q000097:blood* / Q000150:complications / Q000473:pathology*
chemical_list: D017430:Prostate-Specific Antigen
keywords: Benign prostatic hyperplasia; Biopsie de la prostate; Cancer de la prostate; France; Hypertrophie bénigne de la prostate; PSA; PSA testing; Population-based study; Prostate biopsy; Prostate cancer; Étude observationnelle