title: Amygdala Atrophy in MCI/Alzheimer's Disease in the BIOCARD cohort based on Diffeomorphic Morphometry.
abstract: Surface-based deformation markers obtained from diffeomorphic mapping of the amygdala are used to study specific atrophy patterns in a combined mild cognitively impaired and demented cohort compared with cognitively normal aging subjects. Statistical analysis demonstrates with high significance in a small sample of legacy data that deformation-based morphometry provides sensitive markers for locating atrophy in the amygdala. With respect to a high-field amygdala atlas, significant atrophy was found in the basomedial and lateral nucleus subregions.
authors: Center for Imaging Science, Johns Hopkins University.
authors: Michael I
authors: MI
authors: Miller
authors: Institute for Computational Medicine, Johns Hopkins University.
authors: Laurent
authors: L
authors: Younes
authors: Departmemt of Biomedical Engineering, Johns Hopkins University.
authors: J Tilak
authors: JT
authors: Ratnanather
authors: Department of Applied Mathematics and Statistics, Johns Hopkins University.
authors: Timothy
authors: T
authors: Brown
authors: Department of Radiology, Johns Hopkins University School of Medicine.
authors: Tommy
authors: T
authors: Reigel
authors: Department of Neurology, Johns Hopkins University School of Medicine.
authors: Huong
authors: H
authors: Trinh
authors: Xiaoying
authors: X
authors: Tang
authors: Peter
authors: P
authors: Barker
authors: Susumu
authors: S
authors: Mori
authors: Marilyn
authors: M
authors: Albert