title: The early history of odontogenic ghost cell lesions: from Thoma to Gorlin.
abstract: To reappraise the early history of odontogenic ghost cell lesions (OGCL), the extensive world literature published from 1838 to 1962 was reviewed. In light of the long history of OGCL, the term "calcifying epithelioma of Malherbe" first appeared in a 1931 French report, and the term "ghost cells" had its origin in two American seminal articles by Thoma and Goldman in 1946. Although Gorlin et al. coined the term "calcifying odontogenic cyst" (COC) in 1962, this type of cyst was initially reported three decades earlier by Rywkind in Russia, and almost concurrently by Blood good in the United States and Sato in Japan. In 1948, Willis provided the initial histological evidence of a peripheral COC in his British pathology textbook. Credit for the earliest clinical presentation of odontoma associated calcifying cystic odontogenic tumor belongs to the American radiology textbook by Thoma in 1917. A Scandinavian journal report published in 1953 by Husted and Pindborg was the first to address a dentinogenic ghost cell tumor, and its peripheral counterpart was originally reported in the Swiss literature 7 years later. The current concept of COC was undoubtedly established by Gorlin et al. but the history of OGCL really started with Thoma's pioneering work about a century ago.
authors: Department of Diagnostic Pathology, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, 230-8501, Japan, ide-f@tsurumi-u.ac.jp.
authors: Fumio
authors: F
authors: Ide
authors: Kentaro
authors: K
authors: Kikuchi
authors: Yuji
authors: Y
authors: Miyazaki
authors: Kaoru
authors: K
authors: Kusama
authors: Ichiro
authors: I
authors: Saito
authors: Takashi
authors: T
authors: Muramatsu
mesh_terms: D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D018333:Odontogenic Cyst, Calcifying / Q000266:history*