title: [3+3] annulation of allylic phosphoryl-stabilized carbanions/phosphorus ylides and vinyl azides: a practice strategy for synthesis of polyfunctionalized anilines.
abstract: Tandem Michael addition and Witting or Horner-Wadsworth-Emmons olefination initiated [3+3] annulation between vinyl azides and allylic phosphorus ylides or allylic phosphoryl-stabilized carbanions has been developed. This one-pot protocol furnishes highly functionalized anilines in good to excellent yields under mild, room-temperature conditions. A rational mechanism is also proposed.
authors: Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Science, Zhejiang University, Hangzhou 310058, P. R. China. yyu@zju.edu.cn.
authors: Shen
authors: S
authors: Liu
authors: Wenteng
authors: W
authors: Chen
authors: Jing
authors: J
authors: Luo
authors: Yongping
authors: Y
authors: Yu
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000814:Aniline Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D000838:Anions / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D018360:Crystallography, X-Ray; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008958:Models, Molecular
chemical_list: D000475:Alkenes; D000814:Aniline Compounds; D000838:Anions; D001386:Azides