title: Are maintenance strategies underused in Crohn's disease?
abstract: A key aim in the management of Crohn's disease is to maintain disease remission, whether this has been achieved by medical or surgical treatment. The reasons for doing this are to maintain quality of life, to avoid steroid dependence and to maintain mucosal healing with a view to preventing relapse, hospital admission and surgery, and improving disease natural history. Options for remission maintenance include smoking cessation, thiopurines, methotrexate, anti-TNF-α drugs and surgery. Evidence suggests that in some places now, and in most places in the past, too few patients are/were appropriately treated when in remission, and, in many instances, treatment regimens are/were insufficiently tailored to the patient's individual phenotype, prognosis and/or genotype.
authors: Centre for Digestive Diseases, Institute of Cellular and Molecular Science, Barts and the London, Queen Mary School of Medicine and Dentistry, London, UK.
authors: David
authors: D
authors: Rampton
mesh_terms: D003424:Crohn Disease / Q000188:drug therapy*; D006040:Goals; D006801:Humans; D060046:Maintenance Chemotherapy / Q000706:statistics & numerical data*; D057285:Precision Medicine; D012074:Remission Induction