title: Synthesis of l-Ascorbic Acid Lactone Derivatives.
abstract: A small focused library which comprised of l-AA lactone derivatives was built with a facile method. This reported method was optimized by modifying the acidity of the solvent. As a result, 12 l-AA lactones were synthesized. Among these lactones, lactones 8-12 were new compounds. The cytotoxicity of these synthetic compounds were investigated.
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 China ; Graduate School of the Chinese Academy of Sciences, University of Chinese Academy of Sciences, Beijing, 100049 China.
authors: Li-Dong
authors: LD
authors: Shao
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 China ; Graduate School of the Chinese Academy of Sciences, University of Chinese Academy of Sciences, Beijing, 100049 China.
authors: Ya-Nan
authors: YN
authors: Wu
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 China ; Graduate School of the Chinese Academy of Sciences, University of Chinese Academy of Sciences, Beijing, 100049 China.
authors: Jun
authors: J
authors: Xu
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 China.
authors: Juan
authors: J
authors: He
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 China.
authors: Yu
authors: Y
authors: Zhao
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 China.
authors: Li-Yan
authors: LY
authors: Peng
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 China.
authors: Yan
authors: Y
authors: Li
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 China.
authors: Yu-Rong
authors: YR
authors: Yang
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 China.
authors: Cheng-Feng
authors: CF
authors: Xia
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 China.
authors: Qin-Shi
authors: QS
authors: Zhao
keywords: Cytotoxicity; Focused library; l-Ascorbic acid lactone