title: Simple and fast method for fabrication of endoscopic implantable sensor arrays.
abstract: Here we have developed a simple method for the fabrication of disposable implantable all-solid-state ion-selective electrodes (ISE) in an array format without using complex fabrication equipment or clean room facilities. The electrodes were designed in a needle shape instead of planar electrodes for a full contact with the tissue. The needle-shape platform comprises 12 metallic pins which were functionalized with conductive inks and ISE membranes. The modified microelectrodes were characterized with cyclic voltammetry, scanning electron microscope (SEM), and optical interferometry. The surface area and roughness factor of each microelectrode were determined and reproducible values were obtained for all the microelectrodes on the array. In this work, the microelectrodes were modified with membranes for the detection of pH and nitrate ions to prove the reliability of the fabricated sensor array platform adapted to an endoscope.
authors: Nanobioengineering Laboratory, Institute for Bioengineering of Catalonia (IBEC), Baldiri Reixac, 10-12, Barcelona 08028, Spain. ibogachan@ibecbarcelona.eu.
authors: I Bogachan
authors: IB
authors: Tahirbegi
authors: Nanobioengineering Laboratory, Institute for Bioengineering of Catalonia (IBEC), Baldiri Reixac, 10-12, Barcelona 08028, Spain. malvira@ibecbarcelona.eu.
authors: Margarita
authors: M
authors: Alvira
authors: Nanobioengineering Laboratory, Institute for Bioengineering of Catalonia (IBEC), Baldiri Reixac, 10-12, Barcelona 08028, Spain. jsamitier@ibecbarcelona.eu.
authors: Mònica
authors: M
authors: Mir
authors: Nanobioengineering Laboratory, Institute for Bioengineering of Catalonia (IBEC), Baldiri Reixac, 10-12, Barcelona 08028, Spain. jsamitier@ibecbarcelona.eu.
authors: Josep
authors: J
authors: Samitier
mesh_terms: D003217:Conductometry / Q000295:instrumentation* / Q000379:methods; D004209:Disposable Equipment; D004567:Electrodes, Implanted; D019723:Endoscopes; D004724:Endoscopy / Q000295:instrumentation* / Q000379:methods*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D046228:Microarray Analysis / Q000295:instrumentation* / Q000379:methods; D019919:Prosthesis Implantation / Q000295:instrumentation / Q000379:methods; D014159:Transducers