title: Caffeic acid phenethyl ester and therapeutic potentials.
abstract: Caffeic acid phenethyl ester (CAPE) is a bioactive compound of propolis extract. The literature search elaborates that CAPE possesses antimicrobial, antioxidant, anti-inflammatory, and cytotoxic properties. The principal objective of this review article is to sum up and critically assess the existing data about therapeutic effects of CAPE in different disorders. The findings elaborate that CAPE is a versatile therapeutically active polyphenol and an effective adjuvant of chemotherapy for enhancing therapeutic efficacy and diminishing chemotherapy-induced toxicities.
authors: Department of Pharmacy, COMSATS Institute of Information Technology, Abbottabad 22060, Pakistan.
authors: Ghulam
authors: 0000-0001-5649-5768
authors: G
authors: Murtaza
authors: University College of Pharmacy, University of Punjab, Lahore 54000, Pakistan.
authors: Sabiha
authors: S
authors: Karim
authors: Department of Pharmacy, University of Sargodha, Sargodha 40100, Pakistan.
authors: Muhammad Rouf
authors: MR
authors: Akram
authors: Department of Pharmacy, COMSATS Institute of Information Technology, Abbottabad 22060, Pakistan.
authors: Shujaat Ali
authors: SA
authors: Khan
authors: Department of Pharmacy, COMSATS Institute of Information Technology, Abbottabad 22060, Pakistan.
authors: Saira
authors: S
authors: Azhar
authors: Department of Chemistry, COMSATS Institute of Information Technology, Abbottabad 22060, Pakistan.
authors: Amara
authors: A
authors: Mumtaz
authors: Department of Pharmacy, COMSATS Institute of Information Technology, Abbottabad 22060, Pakistan.
authors: Muhammad Hassham Hassan
authors: MH
authors: Bin Asad
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D002109:Caffeic Acids / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D010626:Phenylethyl Alcohol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D011429:Propolis / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D002109:Caffeic Acids; D011429:Propolis; C055494:caffeic acid phenethyl ester; D010626:Phenylethyl Alcohol