title: Leprosy and lymphatic filariasis comorbidity: the case for an integrated functional limitation grading system.
abstract: Worldwide, both lymphatic filariasis (LF) and leprosy are major causes of morbidity and functional limitation. Despite an abundance of data on the impairment caused by these infections in isolation, there is little data on disability in patients unfortunate enough to be affected by both infections. We present two cases of patients with LF and leprosy comorbidity. Both cases suffer from Grade 2 disability and chronic lymphedema in the same limb (left and right leg, respectively). These morbidities cause significant functional limitation in the patients' activities of daily living. Both LF and leprosy are endemic in India and their comorbid conditions contribute to functional limitation. However, there is still currently no integrated scale for assessment of interventions for functional limitation in these patients. Investigating and managing impairment and functional limitations individually is the least cost effective and sustainable strategy. Considering the similarities of caring for functional limitations in both diseases and assuming its efficacy, augmentation of LF care services with leprosy referral centres may be beneficial. Integrated approaches have been pilot tested at district level in states in India under the title 'Integrated Prevention of Deformity project' (IPoD). Further work is required to identify a reliable, holistic, functional impairment scoring system, which allows for comparison between diseases. This may help promote greater understanding of impairments and functional limitations these cause and allow effective monitoring and evaluation of all aspects, activities and stages of similar programmes.
authors: Timothy Miles
authors: TM
authors: Rawson
authors: P V Ranganadha
authors: PV
authors: Rao
mesh_terms: D015897:Comorbidity; D006233:Persons with Disabilities; D004605:Elephantiasis, Filarial / Q000175:diagnosis* / Q000453:epidemiology; D005260:Female; D006801:Humans; D007194:India; D007918:Leprosy / Q000175:diagnosis* / Q000453:epidemiology; D008297:Male; D008875:Middle Aged