title: Hybrid SPECT/CT Imaging in the Evaluation of Coronary Stenosis: Role in Diabetic Patients.
abstract: Purpose. Our purpose was to combine the results of the MDCT (multidetector computed tomography) morphological data and the SPECT (single-photon emission computed tomography) data using hybrid imaging to overcome the limits of the MDCT in the evaluation of coronary stenosis in diabetic patients with large amount of calcium in the coronary arteries. Method and Materials. 120 diabetic patients underwent MDCT examination and SPECT examination. We evaluated 324 coronary arteries. After the examinations, we merged CT and SPECT images. Results. CT evaluation: 52 (32.8%) coronaries with stenosis ≥ 50%, 228 (70.4%) with stenosis < 50%, and 44 (13.6%) with a doubtful evaluation. SPECT evaluation: 80 (24.7%) areas with hypoperfusion, 232 (71.6%) with normal perfusion, and 12 (3.7%) with a doubtful evaluation. Of 324 coronary arteries and corresponding areas, the hybrid SPECT/CT evaluation showed 92 (28.4%) areas with hypoperfusion, and 232 (71.6%) with normal perfusion. Conclusion. Hybrid CT/SPECT imaging could be useful in the detection of significant coronary stenosis in patients with large amount of coronary calcifications.
authors: Dipartimento di Diagnostica per Immagini, Imaging Molecolare, Radiologia Interventistica e Radioterapia, Fondazione Ospedaliera Policlinico "Tor Vergata", Viale Oxford 81, 00133 Roma, Italy.
authors: Andrea
authors: A
authors: Romagnoli
authors: Dipartimento di Diagnostica per Immagini, Imaging Molecolare, Radiologia Interventistica e Radioterapia, Fondazione Ospedaliera Policlinico "Tor Vergata", Viale Oxford 81, 00133 Roma, Italy.
authors: Orazio
authors: O
authors: Schillaci
authors: Dipartimento di Diagnostica per Immagini, Imaging Molecolare, Radiologia Interventistica e Radioterapia, Fondazione Ospedaliera Policlinico "Tor Vergata", Viale Oxford 81, 00133 Roma, Italy.
authors: Chiara
authors: C
authors: Arganini
authors: Dipartimento di Diagnostica per Immagini, Imaging Molecolare, Radiologia Interventistica e Radioterapia, Fondazione Ospedaliera Policlinico "Tor Vergata", Viale Oxford 81, 00133 Roma, Italy.
authors: Eleonora
authors: E
authors: Gaspari
authors: Dipartimento di Diagnostica per Immagini, Imaging Molecolare, Radiologia Interventistica e Radioterapia, Fondazione Ospedaliera Policlinico "Tor Vergata", Viale Oxford 81, 00133 Roma, Italy.
authors: Aurora
authors: A
authors: Ricci
authors: Dipartimento di Diagnostica per Immagini, Imaging Molecolare, Radiologia Interventistica e Radioterapia, Fondazione Ospedaliera Policlinico "Tor Vergata", Viale Oxford 81, 00133 Roma, Italy.
authors: Daniele
authors: D
authors: Morosetti
authors: Dipartimento di Diagnostica per Immagini, Imaging Molecolare, Radiologia Interventistica e Radioterapia, Fondazione Ospedaliera Policlinico "Tor Vergata", Viale Oxford 81, 00133 Roma, Italy.
authors: Irene
authors: I
authors: Coco
authors: Dipartimento di Diagnostica per Immagini, Imaging Molecolare, Radiologia Interventistica e Radioterapia, Fondazione Ospedaliera Policlinico "Tor Vergata", Viale Oxford 81, 00133 Roma, Italy.
authors: Sonia
authors: S
authors: Crusco
authors: Dipartimento di Medicina Nucleare e Neuroradiologia, IRCCS Neuromed, Via Atinense 18, 86077 Pozzilli, IS, Italy.
authors: Ferdinando
authors: F
authors: Calabria
authors: Dipartimento di Diagnostica per Immagini, Imaging Molecolare, Radiologia Interventistica e Radioterapia, Fondazione Ospedaliera Policlinico "Tor Vergata", Viale Oxford 81, 00133 Roma, Italy.
authors: Massimiliano
authors: M
authors: Sperandio
authors: Dipartimento di Diagnostica per Immagini, Imaging Molecolare, Radiologia Interventistica e Radioterapia, Fondazione Ospedaliera Policlinico "Tor Vergata", Viale Oxford 81, 00133 Roma, Italy.
authors: Giovanni
authors: G
authors: Simonetti