title: DNA adsorption by magnetic iron oxide nanoparticles and its application for arsenate detection.
abstract: Iron oxide nanoparticles adsorb fluorescently labeled DNA oligonucleotides via the backbone phosphate and quench fluorescence. Arsenate displaces adsorbed DNA to increase fluorescence, allowing detection of arsenate down to 300 nM. This is a new way of using DNA: analyte recognition relies on its phosphate instead of the bases.
authors: Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada. liujw@uwaterloo.ca.
authors: Biwu
authors: B
authors: Liu
authors: Juewen
authors: J
authors: Liu
mesh_terms: D000327:Adsorption; D001149:Arsenates / Q000032:analysis*; D004247:DNA / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D007700:Kinetics; D053758:Nanoparticles / Q000737:chemistry*; D013050:Spectrometry, Fluorescence / Q000379:methods*
chemical_list: D001149:Arsenates; D005290:Ferric Compounds; D005456:Fluorescent Dyes; C000499:ferric oxide; D004247:DNA