title: Infection with Devriesea agamarum and Chrysosporium guarroi in an inland bearded dragon (Pogona vitticeps).
abstract: OBJECTIVE
  Description of clinical, microbiological and histopathological findings in a case of deep dermatitis in an inland bearded dragon (Pogona vitticeps) caused by Devriesea agamarum and Chrysosporium guarroi.
  
  
  METHODS
  A 4-year-old male inland bearded dragon, weighing 497 g, was presented at the clinic because the animal was suffering from dysecdysis and chronic skin lesions. Large numbers of bacilli, cocci and hyphal elements were diagnosed during the microscopic examination of the wound exudate. Microbiological analysis of a skin specimen revealed a moderate growth of Enterococcus sp. and D. agamarum. The condition of the bearded dragon improved with combined therapy consisting of ceftiofur hydrochloride, voriconazole and meloxicam. However, 3 months later recrudescence was observed. This time, Clostridium sp. and Chrysosporium sp. were isolated in large numbers. The bearded dragon was euthanized. Histopathology confirmed a severe granulomatous dermatitis with associated fungal hyphae and a severe granulomatous hepatitis with intralesional hyphae. Chrysosporium guarroi was identified by PCR and sequencing in two organs (skin and liver).
  
  
  CONCLUSIONS
  This is the first case of an infection with D. agamarum and C. guarroi in an inland bearded dragon (P. vitticeps). It emphasizes the importance of mycological cultures and specific treatment. Samples of suspected Chrysosporium sp. should be cultured at 30°C for 10-14 days. Early antifungal treatment is necessary to prevent systemic and potentially fatal infection with C. guarroi.
authors: Department for Farm Animals and Veterinary Public Health, Clinic for Avian, Reptile and Fish Medicine, University of Veterinary Medicine Vienna, Vienna, Austria; Clinical Unit of Internal Medicine Small Animals, Department/Clinic for Companion Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria.
authors: Silvana
authors: S
authors: Schmidt-Ukaj
authors: Igor
authors: I
authors: Loncaric
authors: Andrea
authors: A
authors: Klang
authors: Joachim
authors: J
authors: Spergser
authors: Annett-Carolin
authors: AC
authors: Häbich
authors: Zdenek
authors: Z
authors: Knotek
mesh_terms: D039903:Actinobacteria / Q000302:isolation & purification*; D000818:Animals; D002912:Chrysosporium / Q000302:isolation & purification*; D060085:Coinfection / Q000175:diagnosis / Q000382:microbiology / Q000662:veterinary*; D003872:Dermatitis / Q000150:complications / Q000175:diagnosis / Q000382:microbiology / Q000662:veterinary*; D003881:Dermatomycoses / Q000150:complications / Q000175:diagnosis / Q000382:microbiology / Q000662:veterinary*; D016908:Gram-Positive Bacterial Infections / Q000150:complications / Q000175:diagnosis / Q000382:microbiology / Q000662:veterinary*; D008116:Lizards / Q000382:microbiology*; D008297:Male