title: ESCRT: nipping the wound in the bud?
abstract: Rapid repair of plasma membrane wounds is critical for cellular survival. Exocytic patches, membrane tension reduction and endocytosis were previously proposed to mediate resealing. A recent study implicating the ESCRT complex adds to the growing evidence that repair involves removal of damaged plasma membrane, and not simply patching the wound.
authors: Department of Cell Biology and Molecular Genetics, 2134 Bioscience Research Building, University of Maryland, College Park, MD 20742-5815, USA.
authors: T
authors: T
authors: Castro-Gomes
authors: Department of Cell Biology and Molecular Genetics, 2134 Bioscience Research Building, University of Maryland, College Park, MD 20742-5815, USA.
authors: A B
authors: AB
authors: Koushik
authors: Department of Cell Biology and Molecular Genetics, 2134 Bioscience Research Building, University of Maryland, College Park, MD 20742-5815, USA. Electronic address: andrewsn@umd.edu.
authors: N W
authors: NW
authors: Andrews
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000378:metabolism*; D004705:Endocytosis / Q000502:physiology*; D056827:Endosomal Sorting Complexes Required for Transport / Q000378:metabolism*; D005089:Exocytosis / Q000502:physiology*; D006801:Humans
chemical_list: D056827:Endosomal Sorting Complexes Required for Transport
keywords: plasma membrane repair; resealing; wounding