title: Kinetic modelling of coupled transport across biological membranes.
abstract: In this report, we have modelled a secondary active co-transporter (symport and antiport), based on the classical kinetics model. Michaelis-Menten model of enzyme kinetics for a single substrate, single intermediate enzyme catalyzed reaction was proposed more than a hundred years ago. However, no single model for the kinetics of co-transport of molecules across a membrane is available in the literature We have made several simplifying assumptions and have followed the basic Michaelis-Menten approach. The results have been simulated using GNU Octave. The results will be useful in general kinetic simulations and modelling.
authors: Kalyani
authors: K
authors: Korla
authors: Chanchal K
authors: CK
authors: Mitra
mesh_terms: D001692:Biological Transport; D002462:Cell Membrane / Q000378:metabolism*; D004798:Enzymes / Q000378:metabolism*; D006801:Humans; D017136:Ion Transport; D007700:Kinetics; D008433:Mathematics; D008962:Models, Theoretical
chemical_list: D004798:Enzymes