title: May mean platelet volume levels be a predictor in the diagnosis of pelvic inflammatory disease?
abstract: BACKGROUND
  Our aim in this study was to investigate whether mean platelet volume (MPV) value could be used as an early marker to predict pelvic inflammatory disease (PID).
  
  
  METHODS
  Overall, 44 patients with PID and 44 healthy women were included in the study. The control group consisted of 44 women who applied to the clinic for a routine gynaecological check-up, without chronic disease or a history of medication use. Owing to the fact that it would affect thrombocyte function, women who have the following conditions were excluded from the study: women who were taking anticoagulant therapy, oral contraceptives, nonsteroid anti-inflammatory medications and who had chronic diseases. The leukocyte count, platelet count, neutrophil ratio and MPV values were collected from PID and the control group. C reactive protein values of patients with PID were also noted.
  
  
  RESULTS
  MPV values in patients with PID were lower than those in the control group. This reduction in MPV is statistically significant when the PID patient group is compared with the control group (p < 0.001). A negative correlation was discovered between platelet count and MPV values (p = 0.019, r = - 0.425). Receiver-operating curve analysis pointed out that MPV has greater area under curve value than neutrophil rate, leukocyte and platelet count (0.73, 0.64, 0.72 and 0.49 respectively).
  
  
  CONCLUSIONS
  Since the MPV value was significantly decreased in patients with PID, it may serve as an additional and even more valuable marker than leukocyte count in the diagnosis of PID.
authors: Faculty of Medicine, Department of Gynecology and Obstetrics, Harran University, Yenisehir Campus, 63300, Sanlıurfa, Turkey, dr.aincebiyik@gmail.com.
authors: Adnan
authors: A
authors: Incebiyik
authors: Ahmet
authors: A
authors: Seker
authors: Mehmet
authors: M
authors: Vural
authors: Nese
authors: N
authors: Gul Hilali
authors: Aysun
authors: A
authors: Camuzcuoglu
authors: Hakan
authors: H
authors: Camuzcuoglu
mesh_terms: D000328:Adult; D015415:Biomarkers; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000378:metabolism; D016022:Case-Control Studies; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D063847:Mean Platelet Volume; D000292:Pelvic Inflammatory Disease / Q000097:blood* / Q000175:diagnosis*; D010976:Platelet Count; D011237:Predictive Value of Tests
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein