title: [Closed pleural biopsy in the diagnostics of malignant pleural involvement].
abstract: BACKGROUND
  Pleural effusion is a frequent reason for a pulmonologist´s investigation. The cornerstone is to distinguish transudative pleural effusion from exudative pleural effusion. In the case of the exudative pleural effusion the next step is detection of malignant etiology of pleural effusion. We have a variety of any non-invasive or invasive examinations. The pleural biopsy is one of the most important methods for diagnostics of malignant pleural effusion.
  
  
  METHODS
  Two hundred and twenty-two closed pleural biopsies (CPB) were performed in 208 patients with pleural effusion, where the cytologic examination of pleural fluid was negative. The authors evaluated the value of CPB for the diagnosis of malignant pleural involvement.
  
  
  CONCLUSIONS
  Total sensitivity, specificity, accuracy, positive predictive value and negative predictive value were 63.1%, 100%, 73.9%, 100% and 52.8%, but in the group of mesotheliomas these results were 59.1%, 100%, 79.4%, 100% and 70.7%. The incidence of complications and representative sampling of the pleura was mentioned. The authors compared the diagnostic value and the incidence of complications of various diagnostic methods in malignant pleural involvement by data in the literature.
authors: Petr
authors: P
authors: Jakubec
authors: Vítězslav
authors: V
authors: Kolek
authors: Aleš
authors: A
authors: Václavík
authors: Jaromír
authors: J
authors: Zatloukal
authors: Stanislav
authors: S
authors: Losse
authors: Ladislava
authors: L
authors: Kučerová
authors: Tomáš
authors: T
authors: Tichý
authors: Kateřina
authors: K
authors: Musilová
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D003581:Cytodiagnosis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016066:Pleural Effusion, Malignant / Q000473:pathology*; D012680:Sensitivity and Specificity; D013048:Specimen Handling