title: Repeat Fine-Needle Aspiration Biopsy within a Short Interval Does Not Increase the Atypical Cytologic Results for Thyroid Nodules with Previously Nondiagnostic Results.
abstract: OBJECTIVE
  The purpose of this study was to determine whether the recommended waiting period of 3 months is necessary for repeat fine-needle aspiration biopsy (FNAB).
  
  
  METHODS
  A retrospective review of 128 nodules from 126 patients with initial nondiagnostic (ND) results was performed for the period between January 2009 and December 2012. Demographic and clinical factors were recorded including age, sex, time interval between FNABs, and ultrasound (US) factors, i.e. nodule size, location, consistency, suspicious malignant findings and thyroiditis. The time interval was subdivided into </≥5, 10, 15 and 20 weeks after the initial FNAB. The effects on the nuclear atypia were analyzed using the Fisher exact test and the Mann-Whitney U test.
  
  
  RESULTS
  None of the demographic, clinical or US variables was significantly related to the atypical diagnosis of repeat FNAB. The time interval until repeat FNAB was also not related to the atypical diagnosis (p = 0.63, 0.57, 0.23 and 0.48 for 5, 10, 15 and 20 weeks, respectively).
  
  
  CONCLUSIONS
  The timing of repeat FNAB for thyroid nodules with previous ND results did not increase the nuclear atypia on repeat FNAB.
authors: Department of Radiology, University of Inha School of Medicine, Incheon, Korea.
authors: Ha Young
authors: HY
authors: Lee
authors: Jung Hwan
authors: JH
authors: Baek
authors: Hyunkyung
authors: H
authors: Yoo
authors: Jae Kyun
authors: JK
authors: Kim
authors: Myung Kwan
authors: MK
authors: Lim
authors: Young Chae
authors: YC
authors: Chu
authors: Young Hye
authors: YH
authors: Kang
authors: Jae-Yol
authors: JY
authors: Lim
mesh_terms: D000328:Adult; D000368:Aged; D044963:Biopsy, Fine-Needle; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D011237:Predictive Value of Tests; D011379:Prognosis; D015203:Reproducibility of Results; D012189:Retrospective Studies; D013964:Thyroid Neoplasms / Q000473:pathology*; D016606:Thyroid Nodule / Q000473:pathology*; D013997:Time Factors