title: The absolute configuration for inthomycin C: revision of previously published work with a reinstatement of the (3R)-configuration for (-)-inthomycin C.
abstract: Stereochemical evidence is presented to demonstrate that (-)-inthomycin C has (3R)- and not (3S)-stereochemistry. Careful reappraisal of the previously published work2-5 now indicates that the Hatakeyama, Hale, Ryu, and Taylor teams all have synthesized (-)-(3R)-inthomycin C. The newly measured [α]D of pure (-)-(3R)-inthomycin C (98% ee) is -7.9 (c 0.33, CHCl3) and not -41.5 (c 0.1, CHCl3) as was previously reported in 2012.
authors: The School of Chemistry and Chemical Engineering and the Centre for Cancer Research and Cell Biology (CCRCB), The Queen's University Belfast , Stranmillis Road, Belfast BT9 5AG, Northern Ireland, United Kingdom.
authors: Karl J
authors: KJ
authors: Hale
authors: Susumi
authors: S
authors: Hatakeyama
authors: Fumiya
authors: F
authors: Urabe
authors: Jun
authors: J
authors: Ishihara
authors: Soraya
authors: S
authors: Manaviazar
authors: Milosz
authors: M
authors: Grabski
authors: Maciej
authors: M
authors: Maczka
mesh_terms: D015394:Molecular Structure; D010080:Oxazoles / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D010080:Oxazoles; C554877:inthomycin C