title: Evaluation of clinical course and neurocognition in children with self-limited infantile epilepsy in a Turkish cohort study.
abstract: The outcome of children with self-limited infantile epilepsy was reported to be normal psychosocial and cognitive development as a characteristic criterion. We aimed to investigate the clinical course and neurocognitive outcome in children with self-limited infantile epilepsy in a Turkish cohort. The clinical course, electroencephalographic (EEG) characteristics, neuroimaging, treatment, and outcome of children with self-limited infantile epilepsy were retrospectively analyzed. All infants were reevaluated with the Denver Developmental Screening Test in addition to neurologic examination. Of 44 patients, self-limited familial infantile epilepsy was diagnosed in 8 infants (18.2%) and self-limited nonfamilial infantile epilepsy in 28 (63.6%). Interictal EEGs and neurologic examinations were normal in all cases. Fine motor and gross motor skills, language, adaptive personal/social skills were near-normal in all patients with self-limited familial infantile epilepsy. Delay in language parameters was observed in 2 infants with self-limited nonfamilial infantile epilepsy. Language skills should be thoroughly evaluated with detailed neurocognitive screening tests in patients with self-limited infantile epilepsy.
authors: Zeynep Kamil Maternity and Children's Diseases Training and Research Hospital, Department of Pediatrics, Istanbul, Turkey.
authors: Abdulkadir
authors: A
authors: Bozaykut
authors: Zeynep Kamil Maternity and Children's Diseases Training and Research Hospital, Department of Pediatrics, Istanbul, Turkey.
authors: Halil Ural
authors: HU
authors: Aksoy
authors: Zeynep Kamil Maternity and Children's Diseases Training and Research Hospital, Department of Pediatrics, Istanbul, Turkey rabiagonul@hotmail.com.
authors: Rabia Gönül
authors: RG
authors: Sezer
authors: Celal Bayar University School of Medicine, Department of Pediatric Neurology, Manisa, Turkey.
authors: Muzaffer
authors: M
authors: Polat
mesh_terms: D002675:Child, Preschool; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology*; D015331:Cohort Studies; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009460:Neurologic Examination; D009483:Neuropsychological Tests; D014421:Turkey / Q000453:epidemiology
keywords: Denver Developmental Screening Test; infantile seizures; language; self-limited infantile epilepsy