title: Gold-catalyzed 1,3-transposition of ynones.
abstract: An efficient, regioselective gold-catalyzed 1,3-transposition reaction of ynones and diynones has been developed. It was found that stereoelectronic (interrupted conjugation) and electronic (extended conjugation) factors could efficiently govern the regioselectivity of this thermodynamically controlled transformation. The produced conjugated diynones were efficiently transformed into diverse alkyne-substituted five- and six-membered heterocycles.
authors: Department of Chemistry, University of Illinois at Chicago , 845 West Taylor Street, Chicago, Illinois 60608-7061, United States.
authors: Roohollah
authors: R
authors: Kazem Shiroodi
authors: Mohammad
authors: M
authors: Soltani
authors: Vladimir
authors: V
authors: Gevorgyan
mesh_terms: D000480:Alkynes / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D006046:Gold / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000138:chemical synthesis; D007659:Ketones / Q000737:chemistry*
chemical_list: D000480:Alkynes; D006571:Heterocyclic Compounds; D007659:Ketones; D006046:Gold