title: Synthesis and surface-spectroscopic characterization of photoisomerizable glyco-SAMs on Au(111).
abstract: Photoisomerizable glyco-SAMs (self-assembled monolayers), utilizing synthetic azobenzene glycoside derivatives were fabricated. The ultimate goal of this project is to assay the influence of the 3D arrangement of sugar ligands on cell adhesion, and eventually make cell adhesion photoswitchable. However, it is a prerequisite for any biological study on the spatial conditions of carbohydrate recognition, that photoisomerization of the surface molecules can be verified. Here, we employed IRRAS and XPS to spectroscopically characterize glyco-SAMs. In particular and unprecedented to date, we prove reversible E→Z→E isomerization of azobenzene glycoside-terminated SAMs.
authors: Otto Diels Institute of Organic Chemistry, Christiana Albertina University of Kiel, Otto-Hahn-Platz 3/4, 24118 Kiel (Germany), Fax: (+49) 431-8807410.
authors: Vijayanand
authors: V
authors: Chandrasekaran
authors: Hanne
authors: H
authors: Jacob
authors: Finn
authors: F
authors: Petersen
authors: Ketheeswari
authors: K
authors: Kathirvel
authors: Felix
authors: F
authors: Tuczek
authors: Thisbe K
authors: TK
authors: Lindhorst
mesh_terms: D006027:Glycosides / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D013057:Spectrum Analysis / Q000379:methods*; D013499:Surface Properties
chemical_list: D006027:Glycosides; D006046:Gold
keywords: IR spectroscopy; azobenzene; glycosides; photoswitching; self-assembly