title: A nationwide study on the incidence of rhegmatogenous retinal detachment in Denmark, with emphasis on the risk of the fellow eye.
abstract: OBJECTIVE
  To estimate the risk of developing rhegmatogenous retinal detachment (RRD) in the fellow eye in patients with RRD in the first eye and to identify potential risk factors.
  
  
  METHODS
  We used the Danish National Patient Registry to identify all surgeries performed for RRD in Denmark in the period from January 2000 to July 2011.
  
  
  RESULTS
  In 11,451 cases of RRD in the study period, 8,553 cases in 8,081 patients were identified as primary RRD with an annual incidence of 13.7 per 100,000 citizens. There was a significant increase in the number of cases with RRD during the study period that was mainly explained by an increase of cataract surgeries. Four hundred and seventy-one of 7,941 patients with primary RRD on one eye and no other previous eye disease developed an additional RRD in the fellow eye with an overall incidence of 1% per year. Cox analysis revealed male gender, surgery on the lens, and young age as significant risk factors (P < 0.0001).
  
  
  CONCLUSIONS
  Patients with RRD on the first eye have a 100 times greater risk of developing RRD on the second eye, and the risk increases with male gender and surgery on the lens but decreases with age.
authors: *Department of Ophthalmology, Glostrup Hospital, University of Copenhagen, Glostrup, Denmark; and †Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.
authors: Javad N
authors: JN
authors: Hajari
authors: Søren S
authors: SS
authors: Bjerrum
authors: Ulrik
authors: U
authors: Christensen
authors: Jens F
authors: JF
authors: Kiilgaard
authors: Toke
authors: T
authors: Bek
authors: Morten
authors: M
authors: la Cour
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003718:Denmark / Q000453:epidemiology; D005500:Follow-Up Studies; D007839:Functional Laterality; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008875:Middle Aged; D012042:Registries / Q000706:statistics & numerical data; D012163:Retinal Detachment / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D012307:Risk Factors; D017678:Sex Distribution; D014821:Vitrectomy; D055815:Young Adult