title: Model organisms and target discovery.
abstract: The wealth of information harvested from full genomic sequencing projects has not generated a parallel increase in the number of novel targets for therapeutic intervention. Several pharmaceutical companies have realized that novel drug targets can be identified and validated using simple model organisms. After decades of service in basic research laboratories, yeasts, worms, flies, fishes, and mice are now the cornerstones of modern drug discovery programs.:
authors: Serono Reproductive Biology Institute Inc., One Technology Place, Rockland MA 02370, USA. Electronic address:marco.muda@serono.com.
authors: Marco
authors: M
authors: Muda
authors: Serono Reproductive Biology Institute Inc., One Technology Place, Rockland MA 02370, USA.
authors: Sean
authors: S
authors: McKenna