title: Identification of EGF as an important regulator for promoting CYP3A4 expression in human embryonic stem cell-derived hepatocytes using TALEN-based gene targeting.
authors: College of Veterinary Medicine, Jilin University, Changchun 130062, China.
authors: Ming
authors: M
authors: Yin
authors: Shenzhen Stem Cell Engineering Laboratory, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen 518055, China.
authors: Huan
authors: H
authors: Yang
authors: Shenzhen Stem Cell Engineering Laboratory, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen 518055, China.
authors: Xiaohua
authors: X
authors: Su
authors: College of Veterinary Medicine, Jilin University, Changchun 130062, China.
authors: Ziyi
authors: Z
authors: Li
authors: College of Veterinary Medicine, Jilin University, Changchun 130062, China.
authors: Zhanpeng
authors: Z
authors: Yue
authors: College of Veterinary Medicine, Jilin University, Changchun 130062, China.
authors: Xueming
authors: X
authors: Zhang
authors: Shenzhen Stem Cell Engineering Laboratory, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen 518055, China.
authors: Da
authors: D
authors: Sun
authors: Shenzhen Stem Cell Engineering Laboratory, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen 518055, China. Electronic address: shiyan@pkusz.edu.cn.
authors: Yan
authors: Y
authors: Shi
authors: College of Veterinary Medicine, Jilin University, Changchun 130062, China; Academy of Military Medical Sciences, Beijing 100871, China. Electronic address: lidx@bmi.ac.cn.
authors: Dexue
authors: D
authors: Li
mesh_terms: D002454:Cell Differentiation; D051544:Cytochrome P-450 CYP3A / Q000235:genetics* / Q000378:metabolism; D004262:DNA Restriction Enzymes / Q000378:metabolism*; D053595:Embryonic Stem Cells / Q000166:cytology / Q000378:metabolism*; D004815:Epidermal Growth Factor / Q000378:metabolism*; D055879:Gene Knock-In Techniques / Q000379:methods; D018390:Gene Targeting; D049452:Green Fluorescent Proteins / Q000235:genetics; D022781:Hepatocytes / Q000166:cytology / Q000378:metabolism*; D006801:Humans
chemical_list: C485184:enhanced green fluorescent protein; D049452:Green Fluorescent Proteins; D004815:Epidermal Growth Factor; D051544:Cytochrome P-450 CYP3A; D004262:DNA Restriction Enzymes