title: Primary immune-mediated thrombocytopenia and immune-mediated neutropenia suspected in a 21-week-old Maine Coon cat.
abstract: METHODS
  A 21-week-old Maine Coon cat presented with an acute-onset coagulopathy. Severe concurrent thrombocytopenia and neutropenia were identified on peripheral blood smears and bone marrow cytology supported a peripheral consumptive process. Other than mild superficial haemorrhage, the cat was clinically well and screening for retroviral diseases, abdominal ultrasound examination, thoracic radiography, haematology and biochemistry panels did not identify an underlying disease. There was no historical pharmaceutical or toxicological trigger noted and the cat was from an area without endemic Ehrlichia spp. There was a rapid resolution of both cytopenias following treatment with immunosuppressive doses of prednisolone, though a mild relapse occurred during gradual prednisolone withdrawal and was responsive to a dose increase.
  
  
  CONCLUSIONS
  This report describes this combination of diseases for the first time in a cat and presents a younger patient than previously described with feline primary immune-mediated haematological disease.
authors: Brisbane Veterinary Specialist Centre, Cnr Old Northern and Keong Rds, Albany Creek, Queensland, 4035, Australia. matt.p.best@googlemail.com.
authors: M P
authors: MP
authors: Best
authors: D R
authors: DR
authors: Fry
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000097:blood* / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D002415:Cats; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage; D009503:Neutropenia / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology / Q000662:veterinary*; D011239:Prednisolone / Q000008:administration & dosage; D013921:Thrombocytopenia / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology / Q000662:veterinary*; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone
keywords: autoimmune diseases; cats; idiopathic thrombocytopenic purpura; neutropenia; thrombocytopenia