title: Enucleation combined with peripheral ostectomy: its role in the management of large cystic ameloblastomas of the mandible.
abstract: OBJECTIVE
  Aggressive resection of a large mandibular cystic ameloblastoma may cause severe deformity and dysfunction, while simple enucleation may carry a high risk of recurrence. The purpose of this study was to evaluate, in terms of both recurrence and the preservation of contour and function, the effectiveness of enucleation combined with peripheral ostectomy (Enu/PO) in managing large mandibular cystic ameloblastomas.
  
  
  METHODS
  Fourteen patients who had large mandibular cystic ameloblastoma (11 unicystic, 3 multicystic) and had been treated with the Enu/PO were reviewed.
  
  
  RESULTS
  The follow-up period was 19-117 months. Using Enu/PO, mandibular continuity was preserved in all patients, and only one patient complained of permanent lip numbness. With bone regeneration, the thinned bone plate significantly thickened and the residual cavity shrank. No pathological fracture occurred. There was recurrence in 3 patients. Two recurrences were treated with radical surgery, and the other with Enu/PO. No new recurrence was found thereafter. All patients were satisfied with their facial appearance.
  
  
  CONCLUSIONS
  The Enu/PO technique is excellent in preserving appearance and functions and with a low risk of recurrence, is a reliable option for the management of large mandibular cystic ameloblastomas.
authors: Dental Clinic, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, PR China; Department of Oral and Maxillofacial Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, PR China.
authors: Sailang
authors: S
authors: Shi
authors: Department of Oral and Maxillofacial Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, PR China.
authors: Yanming
authors: Y
authors: Liu
authors: Department of Oral and Maxillofacial Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, PR China.
authors: Yidan
authors: Y
authors: Shan
authors: Department of Oral and Maxillofacial Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, PR China.
authors: Tao
authors: T
authors: Fu
authors: Department of Oral and Maxillofacial Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, PR China; Department of Oral and Maxillofacial Surgery, Zhejiang University School of Dentistry, Hangzhou, PR China. Electronic address: shifang_zhao@yahoo.com.
authors: Shifang
authors: S
authors: Zhao
mesh_terms: D000293:Adolescent; D000328:Adult; D000369:Aged, 80 and over; D000564:Ameloblastoma / Q000601:surgery*; D001729:Bismuth / Q000627:therapeutic use; D001861:Bone Regeneration / Q000502:physiology; D004338:Drug Combinations; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006847:Hydrocarbons, Iodinated / Q000627:therapeutic use; D006987:Hypesthesia / Q000209:etiology; D008047:Lip Diseases / Q000209:etiology; D008297:Male; D008334:Mandible / Q000473:pathology / Q000601:surgery; D008339:Mandibular Neoplasms / Q000601:surgery*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D010027:Osteotomy / Q000379:methods*; D017060:Patient Satisfaction; D011183:Postoperative Complications; D012189:Retrospective Studies; D015503:Surgical Sponges; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D004338:Drug Combinations; D006847:Hydrocarbons, Iodinated; C045757:bismuth iodoform paraffin paste; D001729:Bismuth
keywords: Ameloblastoma; Cystic; Enucleation; Mandible; Peripheral ostectomy; Treatment