title: Real-time elastography in the evaluation of diffuse thyroid disease: a study based on elastography histogram parameters.
abstract: The purpose of this study was to evaluate the diagnostic performance of quantitative histogram parameters using real-time tissue elastography (RTE) in the diagnosis of patients with diffuse thyroid disease. One hundred and sixteen patients (mean age, 43.7 ± 10.97 y) who had undergone pre-operative staging ultrasonography and RTE were included. For each patient, 11 parameters were obtained from RTE images, from which the "elastic index" was calculated. Diagnostic performance of the elastic index and that of the 11 parameters on RTE were calculated and compared. Of the 116 patients, 31 had diffuse thyroid disease and 85 had normal thyroid parenchyma. Area under the receiver operating characteristic curve (A(z)) of MEAN (average relative value) elasticity was high (0.737), without significant differences from other elasticity values. Diagnostic performance of the elastic index was higher than the MEAN, A(z) = 0.753, without significance (p = 0.802). In conclusion, RTE using the elastic index was found to have good diagnostic performance and may be useful in the diagnosis and management of patients with diffuse thyroid disease.
authors: Department of Radiology, Research Institute of Radiologic Science, Yonsei University College of Medicine, Seoul, Korea.
authors: Jung Hyun
authors: JH
authors: Yoon
authors: Yonsei University College of Medicine, Seoul, Korea.
authors: Jaeheung
authors: J
authors: Yoo
authors: Department of Radiology, Research Institute of Radiologic Science, Yonsei University College of Medicine, Seoul, Korea.
authors: Eun-Kyung
authors: EK
authors: Kim
authors: Department of Radiology, Research Institute of Radiologic Science, Yonsei University College of Medicine, Seoul, Korea.
authors: Hee Jung
authors: HJ
authors: Moon
authors: Department of Research Affairs, Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Korea.
authors: Hye Sun
authors: HS
authors: Lee
authors: Department of Radiology, Research Institute of Radiologic Science, Yonsei University College of Medicine, Seoul, Korea; Department of Radiology, Konyang University Hospital, Konyang University College of Medicine, Metropolitan City Daejeon, Korea.
authors: Jae Young
authors: JY
authors: Seo
authors: Department of Radiology, Research Institute of Radiologic Science, Yonsei University College of Medicine, Seoul, Korea; Department of Radiology, Wonkwang University Sanbon Hospital, Gunpo, Korea.
authors: Hye Young
authors: HY
authors: Park
authors: Department of Radiology, Research Institute of Radiologic Science, Yonsei University College of Medicine, Seoul, Korea; Department of Radiology, Gil Hospital, Gacheon University of Medicine and Science, Incheon, Korea.
authors: Woon-Ju
authors: WJ
authors: Park
authors: Department of Radiology, Research Institute of Radiologic Science, Yonsei University College of Medicine, Seoul, Korea. Electronic address: Docjin@yuhs.ac.
authors: Jin Young
authors: JY
authors: Kwak
mesh_terms: D000328:Adult; D000368:Aged; D003199:Computer Systems; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D025341:Principal Component Analysis; D012372:ROC Curve; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013959:Thyroid Diseases / Q000000981:diagnostic imaging*; D013961:Thyroid Gland / Q000000981:diagnostic imaging*; D055815:Young Adult
keywords: Diffuse thyroid disease; Real-time elastography; Thyroid; Thyroiditis; Ultrasound