title: Modelling arterial pressure waveforms using Gaussian functions and two-stage particle swarm optimizer.
abstract: Changes of arterial pressure waveform characteristics have been accepted as risk indicators of cardiovascular diseases. Waveform modelling using Gaussian functions has been used to decompose arterial pressure pulses into different numbers of subwaves and hence quantify waveform characteristics. However, the fitting accuracy and computation efficiency of current modelling approaches need to be improved. This study aimed to develop a novel two-stage particle swarm optimizer (TSPSO) to determine optimal parameters of Gaussian functions. The evaluation was performed on carotid and radial artery pressure waveforms (CAPW and RAPW) which were simultaneously recorded from twenty normal volunteers. The fitting accuracy and calculation efficiency of our TSPSO were compared with three published optimization methods: the Nelder-Mead, the modified PSO (MPSO), and the dynamic multiswarm particle swarm optimizer (DMS-PSO). The results showed that TSPSO achieved the best fitting accuracy with a mean absolute error (MAE) of 1.1% for CAPW and 1.0% for RAPW, in comparison with 4.2% and 4.1% for Nelder-Mead, 2.0% and 1.9% for MPSO, and 1.2% and 1.1% for DMS-PSO. In addition, to achieve target MAE of 2.0%, the computation time of TSPSO was only 1.5 s, which was only 20% and 30% of that for MPSO and DMS-PSO, respectively.
authors: School of Control Science and Engineering, Shandong University, Jinan 250061, China ; School of Information Science and Engineering, Shandong University, Jinan 250100, China ; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
authors: Chengyu
authors: 0000-0002-4515-5773
authors: C
authors: Liu
authors: National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China.
authors: Tao
authors: T
authors: Zhuang
authors: School of Control Science and Engineering, Shandong University, Jinan 250061, China.
authors: Lina
authors: L
authors: Zhao
authors: School of Control Science and Engineering, Shandong University, Jinan 250061, China.
authors: Faliang
authors: F
authors: Chang
authors: School of Control Science and Engineering, Shandong University, Jinan 250061, China.
authors: Changchun
authors: C
authors: Liu
authors: School of Control Science and Engineering, Shandong University, Jinan 250061, China.
authors: Shoushui
authors: S
authors: Wei
authors: School of Control Science and Engineering, Shandong University, Jinan 250061, China.
authors: Qiqiang
authors: Q
authors: Li
authors: Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
authors: Dingchang
authors: 0000-0001-8077-4548
authors: D
authors: Zheng
mesh_terms: D000328:Adult; D062186:Arterial Pressure / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008955:Models, Cardiovascular; D016011:Normal Distribution