title: Therapeutic protocol using growth factors in electrocution wounds--case reports and review of the literature.
abstract: Injuries by high voltage electrocution represent rare and very complex accidents. In order to provide support to surgical therapy, to limit the extension of injuries or to support the natural process of tissue repair, we oriented towards the use of two growth factors, insulin and platelet-enriched plasma (PRP) administered locally, on the injury site. The therapeutic protocol was applied on three cases of electrocution with promising results in reducing the duration of surgical and pharmacological treatment and of time of hospitalization. The influence of growth factors on healing wounds, the mechanism of action and recent therapeutic applications are also discussed.
authors: Clinic of Plastic Surgery and Reconstructive Microsurgery, Bucharest Emergency Hospital, Bucharest, Romania; rteodoreanu@yahoo.com.
authors: Răzvan Nicolae
authors: RN
authors: Teodoreanu
authors: Serban Arghir
authors: SA
authors: Popescu
authors: Ioan
authors: I
authors: Lascăr
authors: Virginia
authors: V
authors: Vulturescu
authors: Alice
authors: A
authors: Grigore
mesh_terms: D002058:Burns, Electric / Q000628:therapy*; D004556:Electric Injuries / Q000628:therapy*; D006801:Humans; D015552:Injections, Intralesional; D007328:Insulin / Q000008:administration & dosage; D036341:Intercellular Signaling Peptides and Proteins / Q000008:administration & dosage* / Q000494:pharmacology; D008297:Male; D053657:Platelet-Rich Plasma; D016038:Skin Transplantation / Q000379:methods; D014945:Wound Healing / Q000187:drug effects
chemical_list: D007328:Insulin; D036341:Intercellular Signaling Peptides and Proteins