title: [Retrospective analysis of the clinical outcomes in 12 recurrent borderline ovarian tumor patients with second fertility-sparing surgery].
abstract: OBJECTIVE
  To analyse the clinical practicability and significance of fertility-sparing surgery for women with recurrent borderline ovarian tumors (BOT).
  
  
  METHODS
  The clinical and pathological recordings of 12 patients suffered from recurrent BOT in the Obstetrics and Gynecology Hospital of Fudan University from Jan.2002 to Dec. 2012 were analyzed retrospectively. The menstruation situation, fertility function, recurrence rate and survival after second conservative surgery were collected and analyzed.
  
  
  RESULTS
  The average onset age of these 12 patients was 26 years, and none of them had procreation before the second operation. The pathological diagnosis were still BOT and the recurrent sites of 10 patients were still restricted to the ovaries.Of the 12 cases, 8 cases of them had normal menstruation functions and 4 cases had less menstrual volumes or longer menstrual periods. Among 6 cases desired for pregnancy after the second operation, 4 cases of them were successful. The spontaneous pregnancy rate was 4/6. The mean duration of follow-up was 53 months (range: 23-97 months) . All recurrent BOT, three cases developed recurrence once more, two cases of them were just be hinted by B ultrasounds and only one cases was approved to be BOT again by a once more surgical pathology. But no disease related deaths occurred.
  
  
  CONCLUSIONS
  The second fertility-sparing surgery may be feasible for women with recurrent BOT who are young and strongly desired for preservation of fertility. The spontaneous pregnancy rate is satisfactory. However, carefully follow-up is still needed.
authors: Department of Gynecologic Oncology, the Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
authors: Ruifang
authors: R
authors: Chen
authors: Department of Gynecologic Oncology, the Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
authors: Tingting
authors: T
authors: Zhu
authors: Department of Gynecologic Oncology, the Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
authors: Hailin
authors: H
authors: Yu
authors: Department of Gynecologic Oncology, the Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
authors: Jing
authors: J
authors: Zhu
authors: Department of Gynecologic Oncology, the Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China. Email:xinludoc@163.com.
authors: Xin
authors: X
authors: Lu
mesh_terms: D000328:Adult; D005260:Female; D059247:Fertility Preservation / Q000379:methods*; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008598:Menstruation; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery*; D018297:Neoplasms, Cystic, Mucinous, and Serous / Q000473:pathology / Q000601:surgery*; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery*; D011183:Postoperative Complications; D011247:Pregnancy; D011256:Pregnancy Outcome; D012086:Reoperation; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult