title: Image-enhanced endoscopy is critical in the surveillance of patients with colonic IBD.
abstract: Cancer risk in patients with inflammatory bowel disease (IBD) involving the colon is high and increases with time. The quality and efficacy of colonoscopic surveillance is variable. Chromoendoscopy with targeted biopsies is superior to standard white light endoscopy with random biopsies. Although commonly practiced, the technique of random colonic biopsies has poor yield for dysplasia and has little clinical consequence. Studies have shown a limited role for electronic-based image-enhanced endoscopy, including narrow band imaging, in detecting IBD dysplasia. Efforts should focus on the dissemination of the technique of chromoendoscopy in routine clinical practice through training and quality metrics.
authors: Molecular Gastroenterology, Leeds Institute of Biomedical and Clinical Sciences, St James University Hospital, University of Leeds, Leeds LS9 7TF, UK. Electronic address: v.subramanian@leeds.ac.uk.
authors: Venkataraman
authors: V
authors: Subramanian
authors: Department of Gastroenterology, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium.
authors: Raf
authors: R
authors: Bisschops
mesh_terms: D001706:Biopsy; D003093:Colitis, Ulcerative / Q000150:complications / Q000473:pathology*; D003106:Colon / Q000473:pathology*; D003113:Colonoscopy / Q000379:methods*; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*; D004396:Coloring Agents; D003424:Crohn Disease / Q000150:complications / Q000473:pathology*; D055088:Early Detection of Cancer; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D062048:Narrow Band Imaging / Q000379:methods*; D061848:Optical Imaging / Q000379:methods; D011230:Precancerous Conditions / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*
chemical_list: D004396:Coloring Agents
keywords: Autofluorescence; Chromoendoscopy; Crohn's disease; FICE; Narrow band imaging; Surveillance; Ulcerative colitis; iSCAN