title: Effect of clinical symptoms on the indication for selective neck dissection for N0 carcinomas of the parotid gland.
abstract: Lymph node metastasis is a major prognostic factor in parotid carcinoma, however, the pre-operative diagnosis of occult nodal metastasis is difficult in clinical N0 (cN0) parotid cancer patients. In addition, the indication of neck dissection in T1-3 cN0 patients is controversial. The current study investigated 17 patients with clinical T1-3 cN0 parotid cancer, and analyzed the correlation between patient symptoms/findings and pathological N status/tumor histological grade. In the statistical analysis, pain was found to significantly correlate with neck metastasis. Furthermore, cN0-staged patients without pain exhibited no neck metastasis. However, no significant correlation was identified between patient symptoms or findings and histological grade. These results indicate the possibility that selective neck dissection can be omitted for T1-3 cN0-staged patients without pain.
authors: Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan.
authors: Takashi
authors: T
authors: Maruo
authors: Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan.
authors: Yasushi
authors: Y
authors: Fujimoto
authors: Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan.
authors: Kenji
authors: K
authors: Yoshida
authors: Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan.
authors: Mariko
authors: M
authors: Hiramatsu
authors: Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan.
authors: Atsushi
authors: A
authors: Suzuki
authors: Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan.
authors: Naoki
authors: N
authors: Nishio
authors: Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan.
authors: Mariko
authors: M
authors: Shimono
authors: Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan.
authors: Tsutomu
authors: T
authors: Nakashima
keywords: clinical symptoms; neck dissection; parotid gland cancer