title: Vitamin D deficiency and altered bone mineral metabolism in HIV-infected individuals.
abstract: Although patients with HIV infection are living decades longer than before with the advent of combination antiretroviral therapy, they have an increased rate of co-morbidities associated with chronic HIV, such as osteoporosis, cardiovascular disease, and immune dysfunction. Many of these complications are known to be affected by vitamin D status in the general population. Thus, the high rate of vitamin D deficiency among HIV-infected patients is alarming. Many observational and cohort studies have demonstrated that vitamin D deficiency is associated with these HIV-related complications, but randomized, placebo-controlled trials are limited. This paper reviews recent data on vitamin D deficiency in HIV infection.
authors: Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA, across3@emory.edu.
authors: Allison Ross
authors: AR
authors: Eckard
authors: Grace A
authors: GA
authors: McComsey
mesh_terms: D015519:Bone Density / Q000502:physiology*; D015658:HIV Infections / Q000150:complications* / Q000473:pathology; D006801:Humans; D012307:Risk Factors; D014807:Vitamin D / Q000031:analogs & derivatives / Q000378:metabolism; D014808:Vitamin D Deficiency / Q000150:complications*
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D