title: Effect of fluoride varnishes containing tri-calcium phosphate sources on remineralization of initial primary enamel lesions.
abstract: The aim of this study was to evaluate the effect of fluoride varnishes containing tri-calcium phosphate on remineralization of primary enamel lesions. Forty-eight sound primary incisors were coated with nail varnish, leaving two 1 x 1 mm windows before being placed in a demineralizing solution for four days. After demineralization, all the specimens were coated with nail varnish over one of the windows and were randomly assigned to one of four groups: Group A: deionized water; Group B: Duraphat Fluoride Varnish; Group C: Clinpro White Varnish; Group D: TCP-fluoride varnish. Polarized light microscopy was used to evaluate initial lesion depth and after a 7-day pH cycle. Lesion depth was measured using a computerized method with the Image-Pro Plus Program. The differences in mean lesion depths were compared among the groups using the One-Way ANOVA and Tukey's multiple comparison tests at a 95% confidence interval. Group A had a significant increase in lesion depth compared to the other groups. No significant differences were found among Groups B, C and D. We concluded fluoride varnishes containing tri-calcium phosphate inhibit progression of initial primary enamel lesions, and the brands tested were not significantly different from each other in efficacy.
authors: Praphasri
authors: P
authors: Rirattanapong
authors: Kadkao
authors: K
authors: Vongsavan
authors: Chavengkiat
authors: C
authors: Saengsirinavin
authors: Tuenjai
authors: T
authors: Pornmahala
mesh_terms: D002130:Calcium Phosphates / Q000494:pharmacology*; D003743:Dental Enamel / Q000187:drug effects* / Q000473:pathology; D005460:Fluorides, Topical / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D007180:Incisor; D010784:Photomicrography; D011897:Random Allocation; D015203:Reproducibility of Results; D012969:Sodium Fluoride / Q000494:pharmacology*; D017001:Tooth Demineralization / Q000188:drug therapy* / Q000473:pathology; D014089:Tooth Remineralization / Q000379:methods*; D014094:Tooth, Deciduous
chemical_list: D002130:Calcium Phosphates; D005460:Fluorides, Topical; C023807:sodium fluoride topical preparation; D012969:Sodium Fluoride; C020243:calcium phosphate