title: Morphofunctional characteristics of the glutathione cycle in peripheral blood erythrocytes of pregnant women with a history of cytomegalovirus infection exacerbation during gestation.
abstract: We studied factors influencing peripheral blood erythrocytes of pregnant women with exacerbation of cytomegalovirus infection during gestation. Cytomegalovirus infection was associated with a decrease in the content of reduced glutathione in erythrocytes and glutathione peroxidase, which leads to H2O2 accumulation in the blood. Exacerbation of cytomegalovirus infection was associated with reduction of glutathione reductase and SOD activities. Erythrocyte antioxidant function and the peripheral blood discocyte count decreased. Accumulation of degenerative erythrocytes is fraught with the risk of anemia in pregnant women.
authors: Far-Eastern Research Center of Physiology and Pathology of Respiration, Siberian Division of the Russian Academy of Medical Sciences, Blagoveshchensk, Russia, Lucenkomt@mail.ru.
authors: M T
authors: MT
authors: Lutsenko
authors: I A
authors: IA
authors: Andrievskaya
authors: O L
authors: OL
authors: Kutepova
mesh_terms: D000293:Adolescent; D000328:Adult; D003586:Cytomegalovirus Infections / Q000097:blood / Q000503:physiopathology*; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D005978:Glutathione / Q000097:blood*; D005979:Glutathione Peroxidase / Q000097:blood; D005980:Glutathione Reductase / Q000097:blood; D006801:Humans; D006861:Hydrogen Peroxide / Q000097:blood; D011247:Pregnancy; D055815:Young Adult
chemical_list: D006861:Hydrogen Peroxide; D005979:Glutathione Peroxidase; D005980:Glutathione Reductase; D005978:Glutathione