title: Genetics patients' perspectives on clinical genomic testing.
abstract: OBJECTIVE
  Advances in next-generation sequencing technologies make it possible to envisage multiple contexts in which genomic tools might be used to enhance patient care. We describe how genetics patients and their caregivers view the promises and perils of clinical genomic testing.
  
  
  METHODS
  Fifty-one interviews with patients and parents of pediatric patients seeking genetic evaluation at an academic medical center.
  
  
  RESULTS
  Themes from interviews include participants' enthusiasm for clinical genomic testing for diagnostic purposes, medical benefits and concerns about emotional and psychosocial burdens resulting from clinical genomic testing.
  
  
  CONCLUSIONS
  By clarifying these patients' and caregivers' views of clinical genomic testing, the findings we report can help to anticipate other patients' reactions to new forms of personalized medicine enabled by genomic technologies.
authors: Department of Bioethics, Case Western Reserve University, Cleveland, OH, USA ; Center for Genetic Research Ethics & Law, Case Western Reserve University, Cleveland, OH, USA.
authors: Michelle L
authors: ML
authors: McGowan
authors: University of Toledo Medical Center, Toledo, OH, USA.
authors: Allison
authors: A
authors: Glinka
authors: Department of Bioethics, Cleveland Clinic, Cleveland, OH, USA.
authors: Janelle
authors: J
authors: Highland
authors: Ohio University College of Osteopathic Medicine, Athens, OH, USA.
authors: George
authors: G
authors: Asaad
authors: Center for Genetic Research Ethics & Law, Case Western Reserve University, Cleveland, OH, USA ; Department of Bioethics, Cleveland Clinic, Cleveland, OH, USA ; Genomic Medicine Institute, Clevel and Clinic, Cleveland, OH, USA.
authors: Richard R
authors: RR
authors: Sharp
keywords: clinical genomic testing; genetics patient; next-generation sequencing; patient attitudes; qualitative research