title: A facile route to 5-methyl-5H-indeno[1,2-c]quinolones via palladium-catalyzed cyclization of 2-alkynylbromobenzenes with N,N-dimethyl-2-alkynylanilines.
abstract: A tandem reaction catalyzed by palladium is developed to provide a facile and simple route for the synthesis of 5-methyl-5H-indeno[1,2-c]quinolones, which can introduce diversity and complexity into the products from readily available starting materials. This transformation proceeds well with good functional group tolerance.
authors: Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China. yykuang@fudan.edu.cn.
authors: Xiaolin
authors: X
authors: Pan
authors: Yong
authors: Y
authors: Luo
authors: Yunyan
authors: Y
authors: Kuang
authors: Guangming
authors: G
authors: Li
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry*; D001969:Bromobenzenes / Q000737:chemistry*; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D003500:Cyclization; D010165:Palladium / Q000737:chemistry*; D015363:Quinolones / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000814:Aniline Compounds; D001969:Bromobenzenes; D015363:Quinolones; D010165:Palladium; C023650:aniline