title: Organization and dynamics of AMPA receptors inside synapses-nano-organization of AMPA receptors and main synaptic scaffolding proteins revealed by super-resolution imaging.
abstract: Progresses in microscopy have often led to major discoveries in neuroscience, and the recent advent of super-resolution microscopy is no exception. In this review, we will show how imaging has advanced our modern vision of synaptic function. More particularly, we will emphasize how novel nanoscopy techniques have helped in deciphering the organization of post-synaptic proteins, offering new insight into the mechanism of synaptic transmission.
authors: University of Bordeaux, Interdisciplinary Institute for Neuroscience, UMR 5297, F-33000 Bordeaux, France; CNRS, UMR 5297, F-33000 Bordeaux, France.
authors: Eric
authors: E
authors: Hosy
authors: University of Bordeaux, Interdisciplinary Institute for Neuroscience, UMR 5297, F-33000 Bordeaux, France; CNRS, UMR 5297, F-33000 Bordeaux, France; Imagine Optic, 18 rue Charles de Gaulle, 91400 Orsay, France.
authors: Corey
authors: C
authors: Butler
authors: University of Bordeaux, Interdisciplinary Institute for Neuroscience, UMR 5297, F-33000 Bordeaux, France; CNRS, UMR 5297, F-33000 Bordeaux, France. Electronic address: jean-baptiste.sibarita@u-bordeaux2.fr.
authors: Jean-Baptiste
authors: JB
authors: Sibarita
mesh_terms: D000818:Animals; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism; D011485:Protein Binding; D021381:Protein Transport; D018091:Receptors, AMPA / Q000378:metabolism*; D013569:Synapses / Q000378:metabolism*; D009435:Synaptic Transmission
chemical_list: D047908:Intracellular Signaling Peptides and Proteins; D018091:Receptors, AMPA