title: Biological markers in haematological malignancies.
abstract: Haematological malignancies comprise a wide spectrum of well-defined entities, and require a risk-adapted treatment. Beside the classical diagnostic tools, haematologists have routinely access to more and more biological markers, which provide different informations about diagnosis, prognosis and targetable status of each individual disease and permit to define a personalized risk-adapted therapeutic strategy. We aim to describe these different biological markers and to pinpoint their accurate role in daily practice.
authors: CHU Clermont-Ferrand, service d'hématologie clinique adulte et de thérapie cellulaire, 63003 Clermont-Ferrand, France ; Clermont Université, Université d'Auvergne, EA7283, CIC501, BP 10448, 63000 Clermont-Ferrand, France.
authors: Richard
authors: R
authors: Lemal
authors: CHU Clermont-Ferrand, service d'hématologie clinique adulte et de thérapie cellulaire, 63003 Clermont-Ferrand, France ; Clermont Université, Université d'Auvergne, EA7283, CIC501, BP 10448, 63000 Clermont-Ferrand, France.
authors: Olivier
authors: O
authors: Tournilhac
authors: CHU Clermont-Ferrand, service d'hématologie clinique adulte et de thérapie cellulaire, 63003 Clermont-Ferrand, France ; Clermont Université, Université d'Auvergne, EA7283, CIC501, BP 10448, 63000 Clermont-Ferrand, France.
authors: Jacques-Olivier
authors: JO
authors: Bay
mesh_terms: D014408:Biomarkers, Tumor / Q000097:blood*; D019337:Hematologic Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000235:genetics / Q000276:immunology / Q000628:therapy; D006801:Humans; D007120:Immunochemistry / Q000379:methods; D016130:Immunophenotyping / Q000379:methods; D008967:Molecular Biology / Q000379:methods; D018365:Neoplasm, Residual; D010597:Pharmacogenetics
chemical_list: D014408:Biomarkers, Tumor
keywords: biology; diagnosis; haematology; prognosis