title: Long term prospective assessment of living kidney donors: single center experience.
abstract: Virtually, all studies reporting the outcomes of living kidney donation beyond the first year from donation were retrospective. In this prospective study, the outcome of 81 consecutive living kidney donors was thoroughly evaluated. Clinical, laboratory, and radiological assessments were carried out at predonation (basal), 3, 6, 12, and 24 months after donation. The mean age at time of donation was 37.8 ± 9.8 years and the majority was females (75.3%). The mean BMI increased significantly after donation (P < 0.04). The mean serum creatinine levels (mg/dl) were 0.75 ± 0.14, 1.01 ± 0.22, 0.99 ± 0.21, 0.98 ± 0.20, and 0.94 ± 0.20 (P < 0.0001). Likewise, the mean levels of measured creatinine clearance (mL/min) were 148.8 ± 35.7, 94.7 ± 26.6, 95.5 ± 24.6, 96.7 ± 20.2, and 101.6 ± 26.2 (P < 0.0001). The mean 24 hours urinary protein excretion (gm/dL) were 0.09 ± 0.03, 0.19 ± 0.18, 0.16 ± 0.09, 0.18 ± 0.25, and 0.17 ± 0.12 (P < 0.0001). There were significant increases in the means of the longitudinal and transverse diameters of the remaining kidney over time (P < 0.001). Out of 42 female donors, eleven female donors have got successful postdonation pregnancies. There were no reported surgical complications, either intra- or postoperative. Long-term follow-up is necessary for all living kidney donors through local institutional and world registries. This trial is registered with ClinicalTrials.gov NCT00813579.
authors: Department of Nephrology, The Urology and Nephrology Center, Mansoura 35516, Egypt.
authors: Ayman Maher
authors: AM
authors: Nagib
authors: Department of Nephrology, The Urology and Nephrology Center, Mansoura 35516, Egypt.
authors: Ayman Fathi
authors: AF
authors: Refaie
authors: Department of Nephrology, Zagazig University, Zagazig 44519, Egypt.
authors: Yasser Abdelmoniem
authors: YA
authors: Hendy
authors: Department of Radiology, Zagazig University, Zagazig 44519, Egypt.
authors: Magdy Abass Mohmed
authors: MA
authors: Elfawal
authors: Department of Urology, The Urology and Nephrology Center, Mansoura 35516, Egypt.
authors: Ahmed Abdelrahman
authors: AA
authors: Shokeir
authors: Department of Nephrology, The Urology and Nephrology Center, Mansoura 35516, Egypt.
authors: Mohamed Adel
authors: MA
authors: Bakr
authors: Department of Nephrology, The Urology and Nephrology Center, Mansoura 35516, Egypt.
authors: Ahmed Hassan
authors: AH
authors: Neamattala
authors: Department of Nephrology, The Urology and Nephrology Center, Mansoura 35516, Egypt.
authors: Ahmed Farouk
authors: AF
authors: Hamdy
authors: Department of Nephrology, The Urology and Nephrology Center, Mansoura 35516, Egypt.
authors: Khaled Mohamed
authors: KM
authors: Mahmoud
authors: Department of Immunology, The Urology and Nephrology Center, Mansoura 35516, Egypt.
authors: Amani Mostafa
authors: AM
authors: Ismail
authors: Department of Urology, The Urology and Nephrology Center, Mansoura 35516, Egypt.
authors: Mohamed Ahmed
authors: MA
authors: Ghoneim