title: Plexiform neurofibromatosis involving face and oral cavity.
abstract: Plexiform neurofibromas (PNFs) are one of the most common and debilitating complications of neurofibromatosis type I (NF-I). They account for substantial morbidity, disfigurement, functional impairment and are life threatening. PNFs can also be subjected to transformation into malignant peripheral nerve sheath tumor (MPNST). This complication is refractory to treat due to paucity of effective therapies for malignant soft tissue sarcomas in general and also the delay in diagnosis from a preexisting tumor. We report a case of PNF of face involving oral cavity with literature review.
authors: Department of Periodontics, Vinayaka Missions Sankarachariyar Dental College, Salem, Tamil Nadu, India.
authors: Dorairaj
authors: D
authors: Jayachandran
authors: Depatment of Prosthodontia, Vinayaka Missions Sankarachariyar Dental College, Salem, Tamil Nadu, India.
authors: Selvaraj
authors: S
authors: Sunantha
authors: Department of Oral Medicine and Radiology, Sree Mookambika Institute of Dental Sciences, Kanyakumari, Tamil Nadu, India.
authors: Hema
authors: H
authors: Gopalaiah
authors: Department of Oral Medicine and Radiology, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India.
authors: Gajendra
authors: G
authors: Veeraraghavan
keywords: Café- au- lait macules; facial plexiform neurofibromatosis; peripheral nerve sheath tumor; von Recklinghausen's