title: Non-thermal plasmas: novel preventive and curative therapy against melanomas?
abstract: Malignant melanoma is a very aggressive cancer with a very poor short-term prognosis once metastatic. For years, there was no efficient adjuvant therapy after surgery. Chemotherapy and immunotherapy provided hope, but not victory. Further efforts are therefore required, to find new ways to cure this disease. Physics has, once again, opened up new possibilities for treatment, through the use of non-equilibrium atmospheric pressure plasma (NEAPP). The curative potential of this technique was initially assessed on cancer cells, among which melanoma. In a recent issue, Yajima et al. use NEAPP on benign nevi, as a preventive treatment.
authors: Institut Curie, Normal and Pathological Development of Melanocytes, Orsay, France; CNRS UMR3347, Orsay, France; INSERM U1021, Orsay, France; Equipe labellisée - Ligue Nationale contre le Cancer, Orsay, France; University of Paris-Sud, Orsay, France.
authors: Franck
authors: F
authors: Gesbert
authors: Lionel
authors: L
authors: Larue
mesh_terms: D000818:Animals; D001128:Argon / Q000627:therapeutic use*; D018797:Cell Cycle Proteins / Q000235:genetics*; D015972:Gene Expression Regulation, Neoplastic / Q000528:radiation effects*; D009508:Nevus, Pigmented / Q000235:genetics*; D051096:Proto-Oncogene Proteins c-ret / Q000235:genetics*; D011878:Radiotherapy / Q000379:methods*; D012878:Skin Neoplasms / Q000235:genetics*
chemical_list: D018797:Cell Cycle Proteins; D001128:Argon; D051096:Proto-Oncogene Proteins c-ret
keywords: CAP; NEAPP; nevi; prevention; treatment