title: Methotrexate and cyclosporine in psoriasis revisited.
abstract: Methotrexate and cyclosporine - as monotherapy or in combination with biologics or other drugs - still have an important place in the roster of therapeutic options for patients with psoriasis. These medications are safe and effective in carefully selected patients and with careful monitoring. Contraindications are discussed. Data on efficacy and adverse effects-particularly hepatoxicity - are reviewed, and recommendations for monitoring are addressed.
authors: Associate Professor and Vice Chair, University of Connecticut Health Center, Farmington, Connecticut.
authors: Bruce E
authors: BE
authors: Strober
mesh_terms: D016572:Cyclosporine / Q000627:therapeutic use*; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects / Q000627:therapeutic use*; D011565:Psoriasis / Q000188:drug therapy*
chemical_list: D016572:Cyclosporine; D008727:Methotrexate
keywords: TNF; cyclosporine; methotrexate; psoriasis treatment