title: New bis[N-(4-pyridyl)-P-toluene sulfonamide] palladium dichloride a novel fluorophore for determination of lysine amino acid.
abstract: Here, we are describing the study of the chemiluminescence arising from the reaction of bis (2,4,6-trichlorophenyl) oxalate (TCPO) system with new bis [N-(4-pyridyl)-p-toluene sulfonamide] palladium dichloride (BSPC) as a novel luminescent. The optimum concentrations of all reagents such as sodium salicylate (SS) as catalyst, hydrogen peroxide as oxidizing reagent and the relationships between the chemiluminescence intensity and concentrations of TCPO, SS, hydrogen peroxide and BSPC are reported. After optimization the required reagents, the system were used for determination of amino acid lysine, as an effective and selective quencher in the solution functioning in a Stern-Volmer fashion. This resulted in the development of a facile and highly sensitive chemiluminescence detection scheme for the determination of lysine in biological samples. Ultimately, estimating quenching constant Kq of 4.29 × 10(3) M(-1) was successfully carried out. Under the optimal conditions, the evaluated lower and upper detection limits of measurable concentration of lysine are 1.17 × 10(-7) and 3.18 × 10(-4) M, respectively.
authors: Department of Chemistry, Faculty of Science, Lorestan University, 68137-17133, Khorramabad, Iran, a.yari@ymail.com.
authors: Abdollah
authors: A
authors: Yari
authors: Ebrahim
authors: E
authors: Mehdipour
authors: Maryam
authors: M
authors: Karami
mesh_terms: D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D008239:Lysine / Q000032:analysis*; D015394:Molecular Structure
chemical_list: D056831:Coordination Complexes; D005456:Fluorescent Dyes; C000598230:bis(N-(4-pyridyl)-P-toluene sulfonamide)palladium dichloride; D008239:Lysine