title: A numerical analysis of the aortic blood flow pattern during pulsed cardiopulmonary bypass.
abstract: In the modern era, stroke remains a main cause of morbidity after cardiac surgery despite continuing improvements in the cardiopulmonary bypass (CPB) techniques. The aim of the current work was to numerically investigate the blood flow in aorta and epiaortic vessels during standard and pulsed CPB, obtained with the intra-aortic balloon pump (IABP). A multi-scale model, realized coupling a 3D computational fluid dynamics study with a 0D model, was developed and validated with in vivo data. The presence of IABP improved the flow pattern directed towards the epiaortic vessels with a mean flow increase of 6.3% and reduced flow vorticity.
authors: a Bioengineering Unit, Magna Graecia University , Catanzaro , Italy.
authors: V
authors: V
authors: Gramigna
authors: M V
authors: MV
authors: Caruso
authors: M
authors: M
authors: Rossi
authors: G F
authors: GF
authors: Serraino
authors: A
authors: A
authors: Renzulli
authors: G
authors: G
authors: Fragomeni
mesh_terms: D001011:Aorta / Q000502:physiology*; D002315:Cardiopulmonary Bypass / Q000379:methods*; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D007423:Intra-Aortic Balloon Pumping; D008955:Models, Cardiovascular; D011673:Pulsatile Flow / Q000502:physiology*; D012039:Regional Blood Flow / Q000502:physiology*
keywords: cardiopulmonary bypass; computational fluid dynamics; intra-aortic balloon pump; multi-scale model