title: One-pot synthesis of highly substituted 4-acetonylindoles via sequential dearomatization and silver-catalyzed domino reaction.
abstract: Synthetically useful 4-acetonylindoles have been conveniently prepared from 2-alkynylanilines and silyl enol ethers using a dearomatization strategy. The two-step/one-pot protocol involves an iodosylbenzene-mediated oxidative dearomatization and a silver-catalyzed domino reaction.
authors: Department of Chemistry, Fudan University , 220 Handan Road, Shanghai 200433, China.
authors: Xin
authors: X
authors: Feng
authors: Huiqing
authors: H
authors: Wang
authors: Bo
authors: B
authors: Yang
authors: Renhua
authors: R
authors: Fan
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000814:Aniline Compounds / Q000737:chemistry*; D002384:Catalysis; D004987:Ethers / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D012821:Silanes / Q000138:chemical synthesis* / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D000814:Aniline Compounds; D004987:Ethers; D007211:Indoles; D012821:Silanes; D012834:Silver