title: Is there specific neurological disorders of primary Sjögren's syndrome?
abstract: Neurological manifestations of primary Sjögren's syndrome are multiple and appear frequently. Depending on data analysis, patient recruitment, and diagnosis criteria used to defined primary Sjögren's syndrome or neurological manifestations, the estimated prevalence is between 0 and 70%. Peripheral neurological complications seem the most common, particularly sensory-motors axonal neuropathies. Neuronopathy seems to be the most specific neurological complication of primary Sjögren's syndrome. Central manifestations of primary Sjögren's syndrome are not uncommon, but the neurological complication's spectrum is not well defined. Neuromyelitis optica is regularly found among central complications. To conclude, although central and peripheral complications of primary Sjögren's syndrome are difficult to assess, partly because of the wide spectrum of possible manifestations, it is around 20%. Neuronopathy is still the most specific complication.
authors: Service de rhumatologie, hôpital de la Cavale-Blanche, CHU de Brest, 29609 Brest cedex, France.
authors: Guillermo
authors: G
authors: Carvajal Alegria
authors: Service de rhumatologie, hôpital de la Cavale-Blanche, CHU de Brest, 29609 Brest cedex, France.
authors: Dewi
authors: D
authors: Guellec
authors: Service de rhumatologie, hôpital de la Cavale-Blanche, CHU de Brest, 29609 Brest cedex, France.
authors: Valérie
authors: V
authors: Devauchelle-Pensec
authors: Service de rhumatologie, hôpital de la Cavale-Blanche, CHU de Brest, 29609 Brest cedex, France. Electronic address: alain.saraux@chu-brest.fr.
authors: Alain
authors: A
authors: Saraux
mesh_terms: D006801:Humans; D009422:Nervous System Diseases / Q000209:etiology / Q000276:immunology*; D010523:Peripheral Nervous System Diseases / Q000209:etiology / Q000276:immunology; D012859:Sjogren's Syndrome / Q000150:complications / Q000276:immunology*
keywords: Neurology; Sjögren's syndrome