title: Vitamin E prevents glucose metabolism alterations induced by static magnetic field in rats.
abstract: In the present study, we investigate the effects of a possible protective role of vitamin E (vit E) or selenium (Se) on glucose metabolism disruption induced by static magnetic field (SMF) in rats. Rats have been exposed to SMF (128 mT, 1 h/day during 5 days). Our results showed that SMF failed to alter body weight and relative liver weight. Our data demonstrated that exposure to SMF increased (+21 %) blood glucose level and caused a decrease (-15 %) in liver glycogen content. Moreover, the same treatment induced a reduction of pancreatic islet area. Interestingly, supplementation with vit E (DL α-tocopherol acetate, 150 mg/kg per os during 5 days) prevented alterations induced by SMF on glucose metabolism and liver glycogen content, whereas supplementation with Se (Na2SeO3, 0.20 mg/l, in drinking water for 4 weeks) restored only hepatic glycogen contents. By contrast, both vit E and Se failed to correct the area of pancreatic islets.
authors: Laboratoire de Physiologie Intégrée, Faculté des Sciences de Bizerte, 7021, Jarzouna, Tunisia, ghodhbanes@yahoo.fr.
authors: Soumaya
authors: S
authors: Ghodbane
authors: Salem
authors: S
authors: Amara
authors: Aida
authors: A
authors: Lahbib
authors: Karim
authors: K
authors: Louchami
authors: Abdullah
authors: A
authors: Sener
authors: Mohsen
authors: M
authors: Sakly
authors: Hafedh
authors: H
authors: Abdelmelek
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D005947:Glucose / Q000378:metabolism*; D006003:Glycogen / Q000378:metabolism; D007515:Islets of Langerhans / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D060526:Magnetic Fields; D008297:Male; D017208:Rats, Wistar; D012643:Selenium / Q000494:pharmacology; D014810:Vitamin E / Q000494:pharmacology*
chemical_list: D001786:Blood Glucose; D014810:Vitamin E; D006003:Glycogen; D012643:Selenium; D005947:Glucose