title: The potential of metabonomics in drug safety and toxicology.
abstract: Metabonomics (or metabolomics) defines a global profile of the metabolites in a cell, tissue or organism using either (1)H NMR spectroscopy or mass spectrometry in conjunction with statistical pattern recognition. Unlike other functional genomic tools, it is high-throughput and cheap on a per sample basis, providing a rapid screen for large scale drug toxicity testing and screening of large populations. However, for its widespread use in toxicology there is an urgent need for biomarker databases.:
authors: Department of Biochemistry, Tennis Court Road, University of Cambridge, Cambridge, UK CB2 1GA. Electronic address:jlg40@mole.bio.cam.ac.uk.
authors: Julian L
authors: JL
authors: Griffin