title: [Expression and clinical significance of 6-phosphofructo-1-kinase in nasopharyngeal carcinoma].
abstract: OBJECTIVE
  The aim of this study is to investigate the expression and clinical significance of 6-phosphofructo-1-kinase in nasopharyngeal carcinoma biopsy samples.
  
  
  METHODS
  Sixty-one biopsy samples were detected, including 41 tissues samples from patients with nasopharyngeal carcinoma and 20 tissues samples from patients with chronic nasopharyngitis as control group. 6-phosphofructo 1 kinase mRNA expression was detected by RTPCR.
  
  
  RESULTS
  It was observed that the expression levels of 6 phosphofructo-1-kinase mRNA in nasopharyngeal carcinoma tissues were higher than in the chronic inflammatory tissues. And the expression levels in patients with lymph node metastasis were higher than without lymph nod metastasis.
  
  
  CONCLUSIONS
  6-phosphofructo-1-kinase may be a marker in occurrence and metastasis of nasopharyngeal carcinoma.
authors: Shuo
authors: S
authors: Li
authors: Zhende
authors: Z
authors: Du
authors: Jinliang
authors: J
authors: Gao
authors: Chunsheng
authors: C
authors: Gao
authors: Fei
authors: F
authors: Li
authors: Qiong
authors: Q
authors: Yang
authors: Banghua
authors: B
authors: Lu
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism*; D002277:Carcinoma; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D000077274:Nasopharyngeal Carcinoma; D009303:Nasopharyngeal Neoplasms / Q000378:metabolism* / Q000473:pathology; D010732:Phosphofructokinase-1 / Q000235:genetics / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism*
chemical_list: D014408:Biomarkers, Tumor; D012333:RNA, Messenger; D010732:Phosphofructokinase-1; C068652:1-phosphofructokinase