title: Neural stem cell quiescence comes to an un-sticky end.
abstract: Cell-cell interactions, a key feature of the stem cell niche, regulate many aspects of stem cell behaviour. N-cadherin-mediated anchorage of neural stem cells within the adult neural niche maintains stem cell quiescence, and its release by the metalloproteinase MT5-MMP promotes neural stem cell activation.
authors: MRC Centre for Regenerative Medicine, SCRM Building, Edinburgh bioQuarter, 5 Little France Drive, Edinburgh, EH16 4UU, UK.
authors: Katherine R
authors: KR
authors: Long
authors: MRC Centre for Regenerative Medicine, SCRM Building, Edinburgh bioQuarter, 5 Little France Drive, Edinburgh, EH16 4UU, UK.
authors: Charles
authors: C
authors: Ffrench-Constant
mesh_terms: D000818:Animals; D015820:Cadherins / Q000378:metabolism*; D053504:Matrix Metalloproteinases, Membrane-Associated / Q000378:metabolism*; D058953:Neural Stem Cells / Q000166:cytology* / Q000201:enzymology*
chemical_list: D015820:Cadherins; D053504:Matrix Metalloproteinases, Membrane-Associated; C118502:Mmp24 protein, mouse