title: Consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids.
abstract: The synthesis of six cyclic depsipeptoids inspired by the natural depsipeptide sansalvamide A is described. An efficient and fast synthetic strategy was developed using a combination of consecutive isocyanide-based multicomponent reactions (Ugi and Passerini reactions). This methodology can be used to access a variety of cyclic oligodepsipeptoids.
authors.affiliation: Laboratório de Química Metodológica e Orgânica Sintética, Instituto de Química, Universidade de Brasília, CP 4478, 70910-970 Brasília-DF, Brazil.
authors.forename: Angélica de Fátima S
authors.initials: Ade F
authors.lastname: Barreto
authors.affiliation: Faculdade UnB Planaltina, Área Universitária Nº 1, Vila Nossa Senhora de Fátima, Planaltina, 73300-000, Brasília, DF, Brazil.
authors.forename: Otilie E
authors.initials: OE
authors.lastname: Vercillo
authors.affiliation: Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, D-06120 Halle (Saale), Germany.
authors.forename: Ludger A
authors.initials: LA
authors.lastname: Wessjohann
authors.affiliation: Laboratório de Química Metodológica e Orgânica Sintética, Instituto de Química, Universidade de Brasília, CP 4478, 70910-970 Brasília-DF, Brazil.
authors.forename: Carlos Kleber Z
authors.initials: CK
authors.lastname: Andrade
keywords: Passerini reaction; Ugi reaction; depsipeptoids; multicomponent reactions; sansalvamide A