title: Structure of large dsDNA viruses.
abstract: Nucleocytoplasmic large dsDNA viruses (NCLDVs) encompass an ever-increasing group of large eukaryotic viruses, infecting a wide variety of organisms. The set of core genes shared by all these viruses includes a major capsid protein with a double jelly-roll fold forming an icosahedral capsid, which surrounds a double layer membrane that contains the viral genome. Furthermore, some of these viruses, such as the members of the Mimiviridae and Phycodnaviridae have a unique vertex that is used during infection to transport DNA into the host.
authors.forename: Thomas
authors.initials: T
authors.lastname: Klose
authors.forename: Michael G
authors.initials: MG
authors.lastname: Rossmann
mesh_terms: D004267:DNA Viruses / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D008958:Models, Molecular