title: Serine in plants: biosynthesis, metabolism, and functions.
abstract: Serine (Ser) has a fundamental role in metabolism and signaling in living organisms. In plants, the existence of different pathways of Ser biosynthesis has complicated our understanding of this amino acid homeostasis. The photorespiratory glycolate pathway has been considered to be of major importance, whereas the nonphotorespiratory phosphorylated pathway has been relatively neglected. Recent advances indicate that the phosphorylated pathway has an important function in plant metabolism and development. Plants deficient in this pathway display developmental defects in embryos, male gametophytes, and roots. We propose that the phosphorylated pathway is more important than was initially thought because it is the only Ser source for specific cell types involved in developmental events. Here, we discuss its importance as a link between metabolism and development in plants.
authors.affiliation: ERI de Biotecnologia i Biomedicina, Departament de Biologia Vegetal, Facultat de Farmàcia, Universitat de València, 46100 Burjassot (Valencia), Spain. Electronic address: roc.ros@uv.es.
authors.forename: Roc
authors.initials: R
authors.lastname: Ros
authors.affiliation: ERI de Biotecnologia i Biomedicina, Departament de Biologia Vegetal, Facultat de Farmàcia, Universitat de València, 46100 Burjassot (Valencia), Spain.
authors.forename: Jesús
authors.initials: J
authors.lastname: Muñoz-Bertomeu
authors.affiliation: Botanical Institute II, Cologne Biocenter, University of Cologne, D-50674 Cologne, Germany.
authors.forename: Stephan
authors.initials: S
authors.lastname: Krueger
mesh_terms: D018506:Gene Expression Regulation, Plant / Q000502:physiology*; D006019:Glycolysis / Q000502:physiology; D010766:Phosphorylation; D010788:Photosynthesis / Q000502:physiology; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism; D018517:Plant Roots; D010944:Plants / Q000378:metabolism*; D012639:Seeds / Q000378:metabolism; D012694:Serine / Q000096:biosynthesis* / Q000378:metabolism; D013312:Stress, Physiological
chemical_list: D010940:Plant Proteins; D012694:Serine
keywords: phosphorylated serine biosynthesis pathway; plants; serine biosynthesis