title: Towards a better understanding of biomarker response in field survey: a case study in eight populations of zebra mussels.
abstract: In order to provide reliable information about responsiveness of biomarkers during environmental monitoring, there is a need to improve the understanding of inter-population differences. The present study focused on eight populations of zebra mussels and aimed to describe how variable are biomarkers in different sampling locations. Biomarkers were investigated and summarised through the Integrated Biomarker Response (IBR index). Inter-site differences in IBR index were analysed through comparisons with morphological data, proteomic profiles and genetic background of the studied populations. We found that the IBR index was a good tool to inform about the status of sites. It revealed higher stress in more polluted sites than in cleaner ones. It was neither correlated to proteomic profiles nor to genetic background, suggesting a stronger influence of environment than genes. Meanwhile, morphological traits were related to both environment and genetic background influence. Together these results attest the benefit of using biological tools to better illustrate the status of a population and highlight the need of consider inter-population difference in their baselines.
authors.affiliation: Laboratoire Interdisciplinaire des Environnements Continentaux (LIEC), Université de Lorraine, UMR 7360 CNRS, Metz, France. Electronic address: sandrine.devin@univ-lorraine.fr.
authors.forename: S
authors.initials: S
authors.lastname: Pain-Devin
authors.affiliation: Laboratoire Interdisciplinaire des Environnements Continentaux (LIEC), Université de Lorraine, UMR 7360 CNRS, Metz, France.
authors.forename: C
authors.initials: C
authors.lastname: Cossu-Leguille
authors.affiliation: Unité Interactions Animal-Environnement EA4689 - Université de Reims Champagne-Ardenne, Reims, France.
authors.forename: A
authors.initials: A
authors.lastname: Geffard
authors.affiliation: Laboratoire Interdisciplinaire des Environnements Continentaux (LIEC), Université de Lorraine, UMR 7360 CNRS, Metz, France.
authors.forename: L
authors.initials: L
authors.lastname: Giambérini
authors.affiliation: Laboratoire Polymères Biopolymères Surfaces, UMR CNRS 6270, Université de Rouen, France.
authors.forename: T
authors.initials: T
authors.lastname: Jouenne
authors.affiliation: Laboratoire Interdisciplinaire des Environnements Continentaux (LIEC), Université de Lorraine, UMR 7360 CNRS, Metz, France.
authors.forename: L
authors.initials: L
authors.lastname: Minguez
authors.affiliation: Laboratoire Polymères Biopolymères Surfaces, UMR CNRS 6270, Université de Rouen, France.
authors.forename: B
authors.initials: B
authors.lastname: Naudin
authors.affiliation: Laboratoire Interdisciplinaire des Environnements Continentaux (LIEC), Université de Lorraine, UMR 7360 CNRS, Metz, France.
authors.forename: M
authors.initials: M
authors.lastname: Parant
authors.affiliation: Laboratoire Interdisciplinaire des Environnements Continentaux (LIEC), Université de Lorraine, UMR 7360 CNRS, Metz, France.
authors.forename: F
authors.initials: F
authors.lastname: Rodius
authors.affiliation: Laboratoire Interdisciplinaire des Environnements Continentaux (LIEC), Université de Lorraine, UMR 7360 CNRS, Metz, France.
authors.forename: P
authors.initials: P
authors.lastname: Rousselle
authors.affiliation: Laboratoire Adaptation & Diversité en Milieu Marin, Université Pierre et Marie Curie - CNRS, UMR 7144, Station Biologique de Roscoff, France.
authors.forename: K
authors.initials: K
authors.lastname: Tarnowska
authors.affiliation: Laboratoire Adaptation & Diversité en Milieu Marin, Université Pierre et Marie Curie - CNRS, UMR 7144, Station Biologique de Roscoff, France.
authors.forename: C
authors.initials: C
authors.lastname: Daguin-Thiébaut
authors.affiliation: Laboratoire Adaptation & Diversité en Milieu Marin, Université Pierre et Marie Curie - CNRS, UMR 7144, Station Biologique de Roscoff, France.
authors.forename: F
authors.initials: F
authors.lastname: Viard
authors.affiliation: Laboratoire Interdisciplinaire des Environnements Continentaux (LIEC), Université de Lorraine, UMR 7360 CNRS, Metz, France.
authors.forename: S
authors.initials: S
authors.lastname: Devin
mesh_terms: D000818:Animals; D015415:Biomarkers; D003710:Demography; D049875:Dreissena / Q000378:metabolism*; D004784:Environmental Monitoring / Q000379:methods*; D005602:France; D040901:Proteomics; D045483:Rivers; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000633:toxicity*
chemical_list: D015415:Biomarkers; D014874:Water Pollutants, Chemical
keywords: Biomarkers; Genetic structure; Populations; Proteomics; Zebra mussels