title: Diagnosis and outcome of pregnancies with prenatally diagnosed fetal dextrocardia.
abstract: OBJECTIVE
  To evaluate the incidence, associated cardiac and extracardiac malformations and clinical outcome of fetuses with dextrocardia.
  
  
  METHODS
  A retrospective review of 3556 fetal echocardiograms between 2000 and 2011 revealed 39 cases of dextrocardia. Dextrocardia was defined as right-sided positioning of the fetal heart. Prenatal and postnatal records of the fetuses were reviewed.
  
  
  RESULTS
  The incidence was 1.1%. Of the 39 fetuses, 22 were primary dextrocardia and 17 were dextroposition. Diaphragmatic hernia was the most common cause of dextroposition with the incidence of 76%. Of the fetuses with dextroposition 35.5% had a cardiac anomaly. The survival rate of dextroposition was 31.2% and none of the survivors had an associated cardiac anomaly. Primary fetal dextrocardia was most common with situs solitus (45.4%), followed by situs ambiguous (36.3%) and then situs inversus totalis (18.1%). Structural cardiac malformations were found in 100%, 80% and 25% of fetuses with situs ambiguous, solitus and inversus, respectively. Of the dextroposition, 47.6% terminated pregnancy, 14.2% resulted in intrauterine death, 9.5% died after birth, and 28.5% survived.
  
  
  CONCLUSIONS
  A wide spectrum of complex cardiac malformations are associated with fetal dextrocardia. Fetal echocardiography enables detection of complex cardiac anomalies so that parents can be appropriately counselled.
authors.affiliation: Department of Pediatrics, Cardiology Unit and.
authors.forename: Funda
authors.initials: F
authors.lastname: Oztunc
authors.forename: Riza
authors.initials: R
authors.lastname: Madazli
authors.forename: Mehmet Aytac
authors.initials: MA
authors.lastname: Yuksel
authors.forename: Selman
authors.initials: S
authors.lastname: Gökalp
authors.forename: Mahmut
authors.initials: M
authors.lastname: Oncul
mesh_terms: D000328:Adult; D003914:Dextrocardia / Q000000981:diagnostic imaging / Q000453:epidemiology*; D004452:Echocardiography; D005260:Female; D006801:Humans; D015994:Incidence; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D014421:Turkey / Q000453:epidemiology; D016216:Ultrasonography, Prenatal; D055815:Young Adult
keywords: Dextrocardia; fetal echocardiography; perinatal outcome; prenatal diagnosis