title: Reoperative lung transplantation for donor-derived pulmonary mucormycosis.
abstract: A 64-year-old male with end-stage lung disease underwent right orthotopic lung transplantation. After doing well initially, he developed acute hypoxemic respiratory failure with allograft pneumonia. Donor operative cultures demonstrated mold of the Mucor species, which were corroborated by donor endobronchial cultures obtained near the right mainstem bronchial anastomosis. The patient was treated with reoperative bilateral orthotopic lung transplantation in combination with antifungal agents. The operation was performed successfully, using lungs donated after cardiac death and treated with ex vivo lung perfusion. The patient has recovered well, remaining on room air with good allograft function, without evidence of fungal disease.
authors.affiliation: Division of Cardiac Surgery, Department of Surgery, University of Maryland Medical Center and School of Medicine, Baltimore, Maryland. Electronic address: krajagopal@smail.umaryland.edu.
authors.forename: Keshava
authors.initials: K
authors.lastname: Rajagopal
authors.affiliation: Division of Cardiac Surgery, Department of Surgery, University of Maryland Medical Center and School of Medicine, Baltimore, Maryland.
authors.forename: A Claire
authors.initials: AC
authors.lastname: Watkins
authors.affiliation: Division of Cardiac Surgery, Department of Surgery, University of Maryland Medical Center and School of Medicine, Baltimore, Maryland.
authors.forename: Marc
authors.initials: M
authors.lastname: Gibber
authors.affiliation: Division of Cardiac Surgery, Department of Surgery, University of Maryland Medical Center and School of Medicine, Baltimore, Maryland.
authors.forename: Zachary N
authors.initials: ZN
authors.lastname: Kon
authors.affiliation: Division of Cardiac Surgery, Department of Surgery, University of Maryland Medical Center and School of Medicine, Baltimore, Maryland.
authors.forename: Pablo G
authors.initials: PG
authors.lastname: Sanchez
authors.affiliation: Division of Pulmonary/Critical Care Medicine, Department of Medicine, University of Maryland Medical Center and School of Medicine, Baltimore, Maryland.
authors.forename: Aldo T
authors.initials: AT
authors.lastname: Iacono
authors.affiliation: Division of Cardiac Surgery, Department of Surgery, University of Maryland Medical Center and School of Medicine, Baltimore, Maryland.
authors.forename: Bartley P
authors.initials: BP
authors.lastname: Griffith
mesh_terms: D006801:Humans; D008172:Lung Diseases, Fungal / Q000601:surgery*; D016040:Lung Transplantation; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000601:surgery*; D012086:Reoperation; D012131:Respiratory Insufficiency / Q000601:surgery*; D013530:Surgical Wound Infection / Q000601:surgery*; D014019:Tissue Donors