title: Studies on copper(I)-catalyzed highly regio- and stereo-selective hydroboration of alkynamides.
abstract: The copper(I)-catalyzed hydroboration of alkynamides with B2pin2 afforded the alkenamide boronates in 66% to nearly quantitative yields with high regio- and stereo-selectivity. It was interesting to note that the regio-selectivity of the reaction is opposite to that observed in the carbometallation reaction of alkynamides, and the resulting alkenyl boronates provided access to α,β-disubstituted (Z)-alkenamides through further elaboration.
authors.affiliation: Department of Applied Chemistry, College of Science, Nanjing Tech University, Nanjing 211816, People's Republic of China. zhuhj@njtech.edu.cn.
authors.forename: Guangke
authors.initials: G
authors.lastname: He
authors.forename: Shan
authors.initials: S
authors.lastname: Chen
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wang
authors.forename: Hai
authors.initials: H
authors.lastname: Huang
authors.forename: Qijun
authors.initials: Q
authors.lastname: Zhang
authors.forename: Dongming
authors.initials: D
authors.lastname: Zhang
authors.forename: Rong
authors.initials: R
authors.lastname: Zhang
authors.forename: Hongjun
authors.initials: H
authors.lastname: Zhu