title: Middle cerebral artery aneurysm endovascular and surgical therapies: comprehensive literature review and local experience.
abstract: The middle cerebral artery is a common location for cerebral aneurysms and is associated with a lower risk of rupture than aneurysms located in the anterior or posterior communicating arteries. No evidence supports the superiority of clipping over coiling to treat middle cerebral artery aneurysm (MCAA) or vice versa. The feasibility of treating the MCAA with endovascular therapy as the first choice of treatment in cohorts of nonselected aneurysms exceeds 90%. A randomized clinical trial comparing the 2 approaches in nonselected cases with long-term follow-up will shed light on which patients may benefit from one approach over another.
authors.affiliation: Department of Neurology, SNN (Stroke, Neurocritical Care, and Neurointerventional) Research Center, Froedtert Hospital, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA; Department of Radiology, SNN (Stroke, Neurocritical Care, and Neurointerventional) Research Center, Froedtert Hospital, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA; Department of Neurosurgery, SNN (Stroke, Neurocritical Care, and Neurointerventional) Research Center, Froedtert Hospital, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA. Electronic address: szaidat@mcw.edu.
authors.forename: Osama O
authors.initials: OO
authors.lastname: Zaidat
authors.affiliation: Department of Neurology, SNN (Stroke, Neurocritical Care, and Neurointerventional) Research Center, Froedtert Hospital, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
authors.forename: Alicia C
authors.initials: AC
authors.lastname: Castonguay
authors.affiliation: Department of Neurology, SNN (Stroke, Neurocritical Care, and Neurointerventional) Research Center, Froedtert Hospital, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
authors.forename: Mohamed S
authors.initials: MS
authors.lastname: Teleb
authors.affiliation: Department of Neurology, SNN (Stroke, Neurocritical Care, and Neurointerventional) Research Center, Froedtert Hospital, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
authors.forename: Kaiz
authors.initials: K
authors.lastname: Asif
authors.affiliation: Department of Neurology, SNN (Stroke, Neurocritical Care, and Neurointerventional) Research Center, Froedtert Hospital, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
authors.forename: Ayman
authors.initials: A
authors.lastname: Gheith
authors.affiliation: Department of Neurology, SNN (Stroke, Neurocritical Care, and Neurointerventional) Research Center, Froedtert Hospital, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
authors.forename: Chris
authors.initials: C
authors.lastname: Southwood
authors.affiliation: Department of Neurology, SNN (Stroke, Neurocritical Care, and Neurointerventional) Research Center, Froedtert Hospital, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA; Department of Neurosurgery, SNN (Stroke, Neurocritical Care, and Neurointerventional) Research Center, Froedtert Hospital, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
authors.forename: Glen
authors.initials: G
authors.lastname: Pollock
authors.affiliation: Department of Neurology, SNN (Stroke, Neurocritical Care, and Neurointerventional) Research Center, Froedtert Hospital, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA; Department of Radiology, SNN (Stroke, Neurocritical Care, and Neurointerventional) Research Center, Froedtert Hospital, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA; Department of Neurosurgery, SNN (Stroke, Neurocritical Care, and Neurointerventional) Research Center, Froedtert Hospital, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
authors.forename: John R
authors.initials: JR
authors.lastname: Lynch
mesh_terms: D057510:Endovascular Procedures; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000601:surgery*; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging; D011859:Radiography
keywords: Aneurysm; Clipping; Coiling; Endovascular; Intracranial aneurysm; Middle cerebral artery