title: Selective and simultaneous determination of trace bisphenol A and tebuconazole in vegetable and juice samples by membrane-based molecularly imprinted solid-phase extraction and HPLC.
abstract: Nanofibrous molecularly imprinted membranes (nano-MIMs) with multi-analyte selectivity were prepared by encapsulating two types of molecularly imprinted polymer nanoparticles (MIP-NPs) into electrospun polyvinyl alcohol nanofibers. The obtained nano-MIMs maintained high molecular selectivity offered by each of the MIP-NPs. Nano-MIM embedding BPA-imprinted nanoparticles and TBZ-imprinted nanoparticles together showed the highest binding selectivity for acid bisphenol A (BPA) and basic tebuconazole (TBZ). This nano-MIM was used as affinity material of membrane-based molecularly imprinted solid-phase extraction (m-MISPE) to extract trace BPA and TBZ in vegetables and juices simultaneously. The recoveries of BPA and TBZ from different samples were higher than 70.33% with RSDs lower than 9.57%. m-MISPE gave better HPLC separation efficiencies and higher recoveries than conventional SPE based on C18/SCX. Multi-analyte selective m-MISPE combined with HPLC realized selective and simultaneous determination of several trace analytes with opposite charges/polarities in different food samples.
authors.affiliation: Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
authors.forename: Ya-Ting
authors.initials: YT
authors.lastname: Wu
authors.affiliation: Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
authors.forename: Yan-Hong
authors.initials: YH
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
authors.forename: Meng
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Liu
authors.affiliation: Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
authors.forename: Ying-Chun
authors.initials: YC
authors.lastname: Wan
authors.affiliation: Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Huang
authors.affiliation: Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China; Pure and Applied Biochemistry, Center for Chemistry and Chemical Engineering, Lund University, Box 124, SE 22 100 Lund, Sweden.
authors.forename: Lei
authors.initials: L
authors.lastname: Ye
authors.affiliation: Bureau of Health Supervision, Health Department of Hubei Province, #6 Zhuodaoquan North Street, Wuhan, Hubei 430079, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhou
authors.affiliation: Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China. Electronic address: yunshi31@163.com.
authors.forename: Yun
authors.initials: Y
authors.lastname: Shi
authors.affiliation: Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China. Electronic address: lubin@mails.tjmu.edu.cn.
authors.forename: Bin
authors.initials: B
authors.lastname: Lu
mesh_terms: D001559:Benzhydryl Compounds / Q000032:analysis*; D001628:Beverages / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D053758:Nanoparticles / Q000737:chemistry; D010636:Phenols / Q000032:analysis*; D011108:Polymers / Q000737:chemistry; D052616:Solid Phase Extraction / Q000379:methods*; D014230:Triazoles / Q000032:analysis*; D014675:Vegetables / Q000737:chemistry*; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D010636:Phenols; D011108:Polymers; D014230:Triazoles; C087114:tebuconazole; C006780:bisphenol A; D000098826:Bisphenol A Compounds
keywords: 4-Vinylpyridine (PubChem CID: 7502); Azobisisobutyronitrile (PubChem CID: 6547); Bisphenol A; Bisphenol A (PubChem CID: 6623); Bisphenol C (PubChem CID: 6620); Bisphenol Z (PubChem CID: 232446); Electrospun nanofibrous membrane; Estradial (PubChem CID: 5757); Flutriafol (PubChem CID: 91727); Hexaconazole (PubChem CID: 66461); Hydroquinone (PubChem CID: 785); Membrane-based molecularly imprinted solid-phase extraction; Methacrylic acid (PubChem CID: 4093); Molecularly imprinted polymers; Penconazole (PubChem CID: 91693); Tebuconazole; Tebuconazole (PubChem CID: 86102); Vegetable and juice samples; trimethylolpropane trimethacrylate (PubChem CID: 18689)