title: Double-tuned radiofrequency coil for (19)F and (1)H imaging.
abstract: We developed a double-tuned radiofrequency (RF) coil using a novel circuit method to double tune for fluorine-19 (19F) and 1H magnetic resonance imaging, whose frequencies are very close to each other. The RF coil consists of 3 parallel-connected series inductor capacitor circuits. A computer simulation for our double-tuned RF coil with a phantom demonstrated that the coil has tuned resonant frequency and high sensitivity for both 19F and 1H. Drug distribution was visualized at 7 tesla using this RF coil and a rat administered perfluoro 15-crown-5-ether emulsion. The double-tune RF coil we developed may be a powerful tool for 19F and 1H imaging.
authors.affiliation: Central Research Laboratory, Hitachi, Ltd.
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Otake
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Soutome
authors.forename: Koji
authors.initials: K
authors.lastname: Hirata
authors.forename: Hisaaki
authors.initials: H
authors.lastname: Ochi
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Bito
mesh_terms: D000818:Animals; D003198:Computer Simulation; D043844:Crown Ethers / Q000008:administration & dosage; D004867:Equipment Design; D005260:Female; D066235:Fluorine-19 Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000295:instrumentation* / Q000379:methods*; D019047:Phantoms, Imaging; D011522:Protons; D011846:Radio Waves; D051381:Rats; D017208:Rats, Wistar; D012680:Sensitivity and Specificity
chemical_list: D043844:Crown Ethers; D011522:Protons; C042148:15-crown-5