title: Pathological characteristics of esophageal cancer.
abstract: The pathological characteristics of esophageal squamous cell carcinoma, which include regularly occurring multiple carcinogenic lesions (MLs), severe dysplasia (SD) and direct intramural infiltration (DI), were investigated using large pathological sections. A total of 52 esophageal cancer patients underwent surgical resection and were diagnosed with esophageal squamous cell carcinoma. Large sections of the surgical resection specimens were then made for pathological examination. The actual length of the carcinoma was calculated during surgery from the length determined microscopically. ML, SD and DI were identified during pathological examination of the large sections by microscope and were statistically analyzed. The lesion lengths obtained by the various inspection methods differed from each other. ML, SD and DI were identified in 15, 28 and 41 patients, respectively. Furthermore, a higher incidence of DI was observed in patients with lymphatic infiltration or those with a later stage of disease. ML, SD and DI were identified as characteristics of esophageal squamous cell carcinoma, and ML and DI were found to correlate with lymphatic infiltration.
authors.affiliation: Department of Radiation Oncology, Affiliated Hospital of Hebei University, Baoding, Hebei 071000, P.R. China.
authors.forename: Hong-Yun
authors.initials: HY
authors.lastname: Shi
authors.affiliation: Department of Radiation Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China.
authors.forename: Shu-Chai
authors.initials: SC
authors.lastname: Zhu
authors.affiliation: Department of Radiation Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China.
authors.forename: Wen-Bin
authors.initials: WB
authors.lastname: Shen
authors.affiliation: Department of Radiation Oncology, Affiliated Hospital of Hebei University, Baoding, Hebei 071000, P.R. China.
authors.forename: Miao-Ling
authors.initials: ML
authors.lastname: Liu
keywords: esophageal squamous cell carcinoma; large pathological section; pathological characteristics; radiation; surgery