title: CEPP regimen (cyclophosphamide, etoposide, procarbazine and prednisone) as initial treatment for Hodgkin lymphoma patients presenting with severe abnormal liver function.
abstract: ABVD regimen (doxorubicin, bleomycin, vinblastine and dacarbazine) remains the most commonly used front-line therapy for Hodgkin lymphoma. However, atypical and extranodal presentations present challenges to initial therapy, especially in the presence of renal and liver failure. We hereby present two cases of young male patients with atypical presentation of Hodgkin lymphoma with severe abnormal liver function. Patients showed excellent response to cyclophosphamide, etoposide, procarbazine and prednisone (CEPP regimen).
authors.affiliation: Division of Hematology & Oncology, Department of Medicine, Westchester Medical Center, 100 Woods Rd, Valhalla, NY 10595, USA.
authors.forename: Keyur
authors.initials: K
authors.lastname: Thakar
authors.affiliation: Division of Hematology & Oncology, Department of Medicine, Westchester Medical Center, 100 Woods Rd, Valhalla, NY 10595, USA.
authors.forename: Aileen
authors.initials: A
authors.lastname: Novero
authors.affiliation: Division of Hematology & Oncology, Department of Medicine, Westchester Medical Center, 100 Woods Rd, Valhalla, NY 10595, USA.
authors.forename: Arundhati
authors.initials: A
authors.lastname: Das
authors.affiliation: Division of Hematology & Oncology, Department of Medicine, Westchester Medical Center, 100 Woods Rd, Valhalla, NY 10595, USA.
authors.forename: Adriana
authors.initials: A
authors.lastname: Lisinschi
authors.affiliation: Division of Hematology & Oncology, Department of Medicine, Westchester Medical Center, 100 Woods Rd, Valhalla, NY 10595, USA.
authors.forename: Bella
authors.initials: B
authors.lastname: Mehta
authors.affiliation: Division of Hematology & Oncology, Department of Medicine, Westchester Medical Center, 100 Woods Rd, Valhalla, NY 10595, USA.
authors.forename: Tauseef
authors.initials: T
authors.lastname: Ahmed
authors.affiliation: Henan Tumor Hospital, Zhengzhou University, Zhengzhou 450003, China.
authors.forename: Delong
authors.initials: D
authors.lastname: Liu
keywords: CEPP regimen; Hodgkin lymphoma; extranodal lymphoma