title: CoreValve prosthesis causes anterior mitral leaflet perforation resulting in severe mitral regurgitation.
abstract: Percutaneous transcatheter aortic valve replacement (TAVR) has become an alternative to surgical therapy for patients with severe aortic stenosis and high operative risk, but it is associated with specific complications. We report the case of a 72-year-old man who underwent the procedure without complications; however, 45 days after the procedure, he was admitted to the hospital with symptoms of heart failure secondary to severe mitral regurgitation. Necropsy findings showed prosthesis malposition and perforation of the anterior mitral leaflet caused by the contact of the stent of the CoreValve prosthesis (Medtronic, Minneapolis, MN). We discuss TAVR complications, specifically regarding low positioning of the prosthetic valve.
authors.affiliation: Department of Cardiology, Hospital of the Government of the City of Buenos Aires "Dr. Cosme Argerich", Buenos Aires, Argentina.
authors.forename: Alberto
authors.initials: A
authors.lastname: Cozzarin
authors.affiliation: Department of Cardiology, Hospital of the Government of the City of Buenos Aires "Dr. Cosme Argerich", Buenos Aires, Argentina; Ministry of Health of the Government of the City of Buenos Aires, Buenos Aires, Argentina. Electronic address: tcianciulli@gmail.com.
authors.forename: Tomás F
authors.initials: TF
authors.lastname: Cianciulli
authors.affiliation: Department of Surgery, Laval University and Quebec Biomaterials Institute, St François d'Assise Hospital, CHUQ, Quebec, Canada.
authors.forename: Robert
authors.initials: R
authors.lastname: Guidoin
authors.affiliation: Department of Surgery, Laval University and Quebec Biomaterials Institute, St François d'Assise Hospital, CHUQ, Quebec, Canada.
authors.forename: Ze
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Department of Cardiology, Hospital of the Government of the City of Buenos Aires "Dr. Cosme Argerich", Buenos Aires, Argentina.
authors.forename: Jorge A
authors.initials: JA
authors.lastname: Lax
authors.affiliation: Department of Cardiology, Hospital of the Government of the City of Buenos Aires "Dr. Cosme Argerich", Buenos Aires, Argentina.
authors.forename: María C
authors.initials: MC
authors.lastname: Saccheri
authors.affiliation: Department of Cardiology, Hospital of the Government of the City of Buenos Aires "Dr. Cosme Argerich", Buenos Aires, Argentina.
authors.forename: Alejandro
authors.initials: A
authors.lastname: García Escudero
authors.affiliation: Department of Cardiovascular Surgery, Hospital of the Government of the City of Buenos Aires "Dr. Cosme Argerich", Buenos Aires, Argentina.
authors.forename: Jorge E
authors.initials: JE
authors.lastname: Estrada
mesh_terms: D000368:Aged; D001021:Aortic Valve; D006333:Heart Failure / Q000209:etiology; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000293:injuries*; D008944:Mitral Valve Insufficiency / Q000209:etiology*; D011183:Postoperative Complications