title: Sleep-disordered breathing in hypertrophic cardiomyopathy: challenges and opportunities.
abstract: Sleep-disordered breathing (SDB) may be a treatable risk factor in patients with hypertrophic cardiomyopathy (HCM), the most common inherited cardiomyopathy. Evidence suggests a high prevalence of SDB in HCM. We summarize the pathophysiology of SDB as it relates to hypertension, coronary artery disease, atrial fibrillation, and sudden cardiac death in patients with HCM. The implications regarding the care of patients with HCM and SDB are discussed as well as the knowledge deficits needing further exploration.
authors.affiliation: Mayo Clinic, Rochester, MN; International Clinical Research Center, St Anne's Hospital, Brno, Czech Republic. Electronic address: konecny.tomas@mayo.edu.
authors.forename: Tomas
authors.initials: T
authors.lastname: Konecny
authors.affiliation: Mayo Clinic, Rochester, MN.
authors.forename: Virend K
authors.initials: VK
authors.lastname: Somers
mesh_terms: D002312:Cardiomyopathy, Hypertrophic / Q000150:complications* / Q000503:physiopathology; D019468:Disease Management; D014943:Global Health; D006801:Humans; D015994:Incidence; D017286:Polysomnography; D012307:Risk Factors; D012891:Sleep Apnea Syndromes / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology