title: Gait abnormalities in obstructive sleep apnea and impact of continuous positive airway pressure.
abstract: We aimed to determine the effect of continuous positive airway pressure (CPAP) on gait in obstructive sleep apnea (OSA) patients. Gait during single and dual tasks was recorded in 15 OSA patients at baseline and after 8 weeks of CPAP therapy. Step and stance time improved after CPAP. We showed a specific dual-task effect in the condition of verbal fluency. Eight weeks of CPAP seems to improve gait of OSA patients that are specifically disturbed by the dual task of verbal fluency.
authors.affiliation: Department of Neurology, Geneva University Hospitals and University of Geneva, Switzerland; Department of Neurology, Division of Cognitive and Motor Aging, Albert Einstein College of Medicine, Bronx, NY, USA. Electronic address: gilles.allali@hcuge.ch.
authors.forename: G
authors.initials: G
authors.lastname: Allali
authors.affiliation: Sleep Research Laboratory, Geneva University Hospital and University of Geneva, Switzerland.
authors.forename: S
authors.initials: S
authors.lastname: Perrig
authors.affiliation: Department of Neurology, Geneva University Hospitals and University of Geneva, Switzerland.
authors.forename: M
authors.initials: M
authors.lastname: Cleusix
authors.affiliation: Department of Internal Medicine, Rehabilitation and Geriatrics, Geneva University Hospital and University of Geneva, Switzerland.
authors.forename: F R
authors.initials: FR
authors.lastname: Herrmann
authors.affiliation: Division of Pulmonary Diseases, Geneva University Hospital and University of Geneva, Switzerland.
authors.forename: D
authors.initials: D
authors.lastname: Adler
authors.affiliation: Division of Pulmonary Diseases, Geneva University Hospital and University of Geneva, Switzerland.
authors.forename: G
authors.initials: G
authors.lastname: Gex
authors.affiliation: Willy Taillard Laboratory of Kinesiology, Geneva University Hospitals and Geneva University, Switzerland.
authors.forename: S
authors.initials: S
authors.lastname: Armand
authors.affiliation: Division of Pulmonary Diseases, Geneva University Hospital and University of Geneva, Switzerland.
authors.forename: J P
authors.initials: JP
authors.lastname: Janssens
authors.affiliation: Sleep Research Laboratory, Geneva University Hospital and University of Geneva, Switzerland; Univ. Grenoble Alpes, HP2, Inserm, HP2 (U1042), 38043 Grenoble, France.
authors.forename: J L
authors.initials: JL
authors.lastname: Pepin
authors.affiliation: Department of Neurology, Geneva University Hospitals and University of Geneva, Switzerland.
authors.forename: F
authors.initials: F
authors.lastname: Assal
mesh_terms: D000328:Adult; D045422:Continuous Positive Airway Pressure / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D020233:Gait Disorders, Neurologic / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D010865:Pilot Projects; D020181:Sleep Apnea, Obstructive / Q000150:complications*
keywords: Continuous positive airway pressure; Gait disorders/ataxia; Obstructive sleep apnea