title: Adenocarcinoma of the pigmented ciliary epithelium.
abstract: Adenocarcinoma of the pigmented ciliary epithelium is an exceptionally rare eye tumour, with only a few cases reported to date. We encountered such a case in a 50-year-old woman who reported seeing floaters in her right eye. Fundus examination and MRI revealed an elevated lesion located in the ciliary body compressing the lens. The ciliary body was resected under the diagnosis of ciliary adenoma. On histological examination, the tumour exhibited epithelial features with glandular formation and moderate nuclear pleomorphism. The tumour invaded the subepithelial stroma of the ciliary body. Immunohistochemical findings were positive for cytokeratin OSCAR, AE1/AE3, CK7, EMA, S100, Melan A, HMB45, and microphthalmia-associated transcription factor.
authors.affiliation: Department of Pathology and Clinical Laboratories, National Cancer Center Central Hospital, Tokyo, Japan.
authors.forename: Aoi
authors.initials: A
authors.lastname: Sukeda
authors.affiliation: Department of Pathology and Clinical Laboratories, National Cancer Center Central Hospital, Tokyo, Japan.
authors.forename: Taisuke
authors.initials: T
authors.lastname: Mori
authors.affiliation: Department of Opthalamic Tumor, National Cancer Center Central Hospital, Tokyo, Japan.
authors.forename: Shigenobu
authors.initials: S
authors.lastname: Suzuki
authors.affiliation: Department of Pathology and Clinical Laboratories, National Cancer Center Central Hospital, Tokyo, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Ochiai
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis*; D001706:Biopsy; D002924:Ciliary Body / Q000473:pathology*; D003937:Diagnosis, Differential; D005134:Eye Neoplasms / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology*