title: Syphilitic hepatitis treated with doxycycline in an HIV-infected patient and review of the literature.
abstract: An HIV-infected male patient who had sex with men and with a penicillin allergy presented with liver dysfunction due to secondary syphilis and was successfully treated with doxycycline. This case highlights that syphilitic hepatitis may be overlooked in this particular population, and health care providers should be attuned to this diagnosis. Doxycycline may be an acceptable alternative to penicillin for treatment of this clinical syndrome.
authors.affiliation: From the *Department of Medicine, Division of Infectious Diseases, University of Maryland Medical Center, Baltimore, MD; †Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD; and ‡Department of Pathology, University of Maryland Medical Center, Baltimore, MD.
authors.forename: Jacqueline T
authors.initials: JT
authors.lastname: Bork
authors.forename: Thomas
authors.initials: T
authors.lastname: Macharia
authors.forename: Julia
authors.initials: J
authors.lastname: Choi
authors.forename: Bruce L
authors.initials: BL
authors.lastname: Gilliam
authors.forename: Ulrike K
authors.initials: UK
authors.lastname: Buchwald
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000188:drug therapy*; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004318:Doxycycline / Q000627:therapeutic use*; D004342:Drug Hypersensitivity; D006505:Hepatitis / Q000150:complications / Q000188:drug therapy*; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D010406:Penicillins / Q000009:adverse effects; D013587:Syphilis / Q000150:complications / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D010406:Penicillins; D004318:Doxycycline