title: Successful in utero intervention for bilateral renal agenesis.
abstract: BACKGROUND
  We report a case of bilateral renal agenesis treated with serial amnioinfusion in which the newborn survived the newborn period and was able to undergo peritoneal dialysis as a bridge to planned renal transplantation.
  
  
  METHODS
  A 34-year-old woman, gravida 1 para 0, presented at 23 1/7 weeks of gestation with a diagnosis of anhydramnios and bilateral renal agenesis. The patient underwent weekly serial amnioinfusion with the goal of improving fetal pulmonary development. At 28 weeks of gestation, the patient delivered a live newborn who required minimal respiratory support. The neonate is currently 9 months old and is undergoing daily peritoneal dialysis.
  
  
  CONCLUSIONS
  Serial amnioinfusion appears to have mitigated the severe pulmonary compromise that has, in the past, led to the death of newborns with bilateral renal agenesis.
authors.affiliation: Johns Hopkins University School of Medicine, Baltimore, Maryland, and Legacy Maternal Fetal Medicine, Vancouver, Washington.
authors.forename: Jessica L
authors.initials: JL
authors.lastname: Bienstock
authors.forename: Meredith L
authors.initials: ML
authors.lastname: Birsner
authors.forename: Fred
authors.initials: F
authors.lastname: Coleman
authors.forename: Nancy A
authors.initials: NA
authors.lastname: Hueppchen
mesh_terms: D000015:Abnormalities, Multiple / Q000209:etiology / Q000517:prevention & control*; D000328:Adult; D000013:Congenital Abnormalities / Q000628:therapy*; D005260:Female; D005315:Fetal Diseases / Q000628:therapy*; D046128:Fetal Therapies; D006801:Humans; D007231:Infant, Newborn; D007668:Kidney / Q000002:abnormalities*; D007674:Kidney Diseases / Q000150:complications / Q000151:congenital* / Q000628:therapy; D008168:Lung / Q000002:abnormalities*; D008171:Lung Diseases / Q000209:etiology / Q000517:prevention & control*; D010530:Peritoneal Dialysis; D011247:Pregnancy