title: [Cross-sectional study on high-normal blood pressure and chronic kidney disease in occupational physical examination population in Changsha].
abstract: OBJECTIVE
  To investigate the relationship between high-normal blood pressure and chronic kidney disease (CKD) in occupational physical examination population in Changsha.
  
  
  METHODS
  With a convenient sampling method, a cross-sectional survey of representative sample of 11 274 white collar workers was conducted in Changsha between March 2011 and May 2011 in a large comprehensive hospital. All subjects were assigned into 4 groups: a normal blood pressure group, a high-normal blood pressure group, an undiagnosed hypertension group, and a diagnosed hypertension group. Anthropometry, blood pressure, blood sample and urine sample were measured with standard instruments and methodology for all the subjects. Multiple logistic regression analysis was used to identify risk factors for CKD.
  
  
  RESULTS
  The prevalence of CKD in the normal blood pressure, high-normal blood pressure, undiagnosed hypertension, and diagnosed hypertension were 3.31%, 6.60%, 11.78%, and 17.35%, respectively. The prevalence of CKD in males was significantly higher than that in females (P<0.01). For males with high-normal blood pressure, the CKD risk was significantly greater (OR, 1.30; 95% CI:1.03 - 1.63) than those with optimal blood pressure. The logistic regression analysis showed that there was an additive effect of hyperuricemia on CKD risk in men with high-normal blood pressure compared with men with optimal blood pressure (OR, 2.25; 95% CI, 1.59 - 3.19; P<0.05).
  
  
  CONCLUSIONS
  The prevalence of CKD in people with the high-normal blood pressure is 6.60% in occupational physical examination population in Changsha. CKD is a high risk for men with highnormal blood pressure and hyperuricemia is an independent risk factor.
authors.affiliation: Department of Health Management, Third Xiangya Hospital, Central South University, Changsha 410013,China.
authors.forename: Xia
authors.initials: X
authors.lastname: Cao
authors.forename: Xiumei
authors.initials: X
authors.lastname: Xie
authors.forename: Guo
authors.initials: G
authors.lastname: Xu
authors.forename: Hong
authors.initials: H
authors.lastname: Yuan
authors.forename: Zhiheng
authors.initials: Z
authors.lastname: Chen
mesh_terms: D001794:Blood Pressure; D002681:China; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D033461:Hyperuricemia / Q000453:epidemiology; D008297:Male; D010808:Physical Examination; D015995:Prevalence; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology*; D012307:Risk Factors