title: Microincision vitrectomy surgery in vitreomacular traction syndrome of retinitis pigmentosa patients.
abstract: OBJECTIVE
  To investigate long-term retinal changes after microincision pars plana vitrectomy surgery (MIVS) and internal limiting membrane (ILM) peeling outcome in retinitis pigmentosa (RP) patients affected by vitreomacular traction syndrome (VMT) with higher vitreous surface adhesion or coexisting epiretinal membrane (ERM).
  
  
  METHODS
  Eight RP patients suffering from VMT were evaluated by means of best corrected visual acuity (BCVA), anterior and posterior binocular examination, spectral-domain optical coherence tomography (SD-OCT), MP-1 microperimetry (MP-1), and full-field electroretinogram (ERG), before MIVS and ILM peeling and during the 36-month follow-up. Patients were hospitalized for two days after the surgery. Surgical procedure was performed following this schedule: surgical removal of crystalline lens (MICS), MIVS with 23-gauge sutureless system trocars, core vitreous body removal, and balanced-sterile-salin-solution- (BSS-) air-gas (SF6) exchange.
  
  
  RESULTS
  All patients presented visual acuity (VA) increase after MIVS. None of the patients developed ocular hypertension or vitreomacular adhesions during the 3-year follow-up. MP-1 bivariate contour ellipse area (BCEA) was reduced in its dimensions and improved in all patients demonstrating a better fixation.
  
  
  CONCLUSIONS
  MIVS could be the gold standard therapy in RP patients with VMT and higher vitreous surface adhesion or coexisting ERM if medical therapy is not applicable or not effective.
authors.affiliation: Department of Ophthalmology, Polo Pontino, A. Fiorini Hospital, Via Firenze, 04019 Terracina, Italy ; Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
authors.forename: Enzo Maria
authors.initials: EM
authors.lastname: Vingolo
authors.affiliation: Department of Ophthalmology, Polo Pontino, A. Fiorini Hospital, Via Firenze, 04019 Terracina, Italy ; Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
authors.forename: Emanuele
authors.initials: E
authors.lastname: Gerace
authors.affiliation: Department of Ophthalmology, Polo Pontino, A. Fiorini Hospital, Via Firenze, 04019 Terracina, Italy ; Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Valente
authors.affiliation: Department of Ophthalmology, Polo Pontino, A. Fiorini Hospital, Via Firenze, 04019 Terracina, Italy ; Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
authors.forename: Leopoldo
authors.initials: L
authors.lastname: Spadea
authors.affiliation: Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy ; Department of Sense Organs, Centre of Ocular Electrophysiology, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico 155, 00161 Rome, Italy.
authors.forename: Marcella
authors.initials: M
authors.lastname: Nebbioso
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D020127:Recovery of Function; D012174:Retinitis Pigmentosa / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D013577:Syndrome; D014821:Vitrectomy; D014822:Vitreous Body / Q000473:pathology / Q000503:physiopathology