title: Stability of sunscreens containing CePO4: proposal for a new inorganic UV filter.
abstract: Inorganic UV filters have become attractive because of their role in protecting the skin from the damage caused by continuous exposure to the sun. However, their large refractive index and high photocatalytic activity have led to the development of alternative inorganic materials such as CePO4 for application as UV filters. This compound leaves a low amount of white residue on the skin and is highly stable. The aim of this study was to evaluate the physical and chemical stability of a cosmetic formulation containing ordinary organic UV filters combined with 5% CePO4, and, to compare it with other formulations containing the same vehicle with 5% TiO2 or ZnO as inorganic materials. The rheological behavior and chemical stability of the formulations containing these different UV filters were investigated. Results showed that the formulation containing CePO4 is a promising innovative UV filter due to its low interaction with organic filters, which culminates in longer shelf life when compared with traditional formulations containing ZnO or TiO2 filters. Moreover, the recognized ability of CePO4 to leave a low amount of white residue on the skin combined with great stability, suggests that CePO4 can be used as inorganic filter in high concentrations, affording formulations with high SPF values.
authors.affiliation: Department of Chemistry, Faculty of Philosophy, Sciences and Languages of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP 14040-901, Brazil. vitorcseixas@yahoo.com.br.
authors.forename: Vitor C
authors.initials: VC
authors.lastname: Seixas
authors.affiliation: Department of Chemistry, Faculty of Philosophy, Sciences and Languages of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP 14040-901, Brazil. osaserra@usp.br.
authors.forename: Osvaldo A
authors.initials: OA
authors.lastname: Serra
mesh_terms: D002563:Cerium / Q000737:chemistry*; D010710:Phosphates / Q000737:chemistry*; D012212:Rheology; D013473:Sunscreening Agents / Q000737:chemistry*; D014466:Ultraviolet Rays
chemical_list: D010710:Phosphates; D013473:Sunscreening Agents; D002563:Cerium; C048083:cerium phosphate