title: [Risk factors for adverse reactions after protamine administration in adult patients undergoing cardiac surgery- a case report and literature review].
abstract: Protamine is a protein mainly used to reverse anticoagulant effects of heparin during cardiac or vascular surgery with extracorporeal circulation. Adverse events after protamine administration are rare but if they occur they can be catastrophic. Based on a case report with an elective cardiac surgery patient with known allergy to fish, we discuss the related events and risk factors for an adverse reaction after protamine. The patient management and its outcome are presented.
authors.forename: Simone
authors.initials: S
authors.lastname: Brück
authors.forename: Christian
authors.initials: C
authors.lastname: Skrabal
authors.forename: Karl
authors.initials: K
authors.lastname: Träger
authors.forename: Helmut
authors.initials: H
authors.lastname: Reinelt
mesh_terms: D000368:Aged; D000707:Anaphylaxis / Q000209:etiology / Q000628:therapy; D000818:Animals; D006348:Cardiac Surgical Procedures; D004342:Drug Hypersensitivity / Q000628:therapy*; D005260:Female; D005399:Fishes; D005512:Food Hypersensitivity / Q000150:complications*; D006494:Heparin Antagonists / Q000009:adverse effects*; D006801:Humans; D008460:Meat; D019990:Perioperative Care; D011183:Postoperative Complications / Q000628:therapy*; D011479:Protamines / Q000009:adverse effects*; D012307:Risk Factors
chemical_list: D006494:Heparin Antagonists; D011479:Protamines