title: Gestational choriocarcinoma at Ibn Rochd Hospital, Casablanca, 2004-2010.
abstract: The aim of this retrospective study was to determine the frequency, risk factors, management and prognosis of gestational choriocarcinoma at the gynaecology-obstetrics C department of the Ibn Rochd Hospital in Casablanca, Morocco over a 7-year period (2004-2010). There were 18 760 pregnancies in the study period, among which 8 cases of gestational choriocarcinoma were recorded, a frequency of 43/100 000 or 1 case of gestational choriocarcinoma in 2345 pregnancies. Maternal age ranged from 20 to 48 years. It occurred after a hydatidiform mole in 4 cases, after spontaneous miscarriage in 2 and after normal delivery in 2 cases. All the patients presented with bleeding. Metastases were found in 3 patients, including 2 with pulmonary localization. Positive diagnosis was made mainly by ultrasound and human chorionic gonadotropin level and histological confirmation was done for all cases. Polychemotherapy was used to treat 4 cases, monochemotherapy to treat 3 and one case received only radiotherapy. Of the 8 cases, 2 patients died and 6 had complete remission.
authors.affiliation: Centre hospitalier universitaire (CHU) Ibn Rochd, Casablanca (Maroc); Service de gynécologie-obstétrique « C », Centre hospitalier universitaire Ibn Rochd, Casablanca (Maroc); Centre d'Études Doctorales de Biologie Moléculaire et Génétique, Faculté de Médecine et de Pharmacie, Université Hassan II - Aïn Chock, Casablanca (Maroc).
authors.forename: H
authors.initials: H
authors.lastname: Boufettal
authors.affiliation: Service de gynécologie-obstétrique « C », Centre hospitalier universitaire Ibn Rochd, Casablanca (Maroc).
authors.forename: L
authors.initials: L
authors.lastname: Khalkane
authors.affiliation: Service de gynécologie-obstétrique « C », Centre hospitalier universitaire Ibn Rochd, Casablanca (Maroc).
authors.forename: M
authors.initials: M
authors.lastname: Noun
authors.affiliation: Service de gynécologie-obstétrique « C », Centre hospitalier universitaire Ibn Rochd, Casablanca (Maroc).
authors.forename: S
authors.initials: S
authors.lastname: Hermas
authors.affiliation: Service de gynécologie-obstétrique « C », Centre hospitalier universitaire Ibn Rochd, Casablanca (Maroc).
authors.forename: N
authors.initials: N
authors.lastname: Samouh