title: Association between macroscopic appearance of liver lesions and liver histology in dogs with splenic hemangiosarcoma: 79 cases (2004-2009).
abstract: Medical records for 79 dogs with confirmed splenic hemangiosarcoma (HSA) following splenectomy were reviewed for information regarding either the presence or absence of macroscopic liver lesions and the histopathological characteristics of the liver. Only 29 of 58 dogs (50%) with grossly abnormal livers had HSA metastasis. No dogs with grossly normal livers had metastasis detected on liver pathology. Gross lesions in the liver such as multiple nodules, dark-colored nodules, and active bleeding nodules were highly associated with malignancy. For the dogs in this study, performing biopsy in a grossly normal liver was a low-yield procedure in dogs with splenic HSA.
authors.affiliation: Department of Small Animal Surgery (D.C., R.S.) and Department of Pathology (T.D.), Animal Medical Center, New York, NY; Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA (K.S.); Department of Small Animal Oncology, Fifth Avenue Veterinary Specialists, New York, NY (A.T.); Department of Small Animal Oncology, Long Island Veterinary Specialists, Plainview, NY (T.A.); and Department of Clinical Studies, Katonah-Bedford Veterinary Center, Bedford Hills, NY (P.B.).
authors.forename: Daphne C
authors.initials: DC
authors.lastname: Clendaniel
authors.forename: Ramesh K
authors.initials: RK
authors.lastname: Sivacolundhu
authors.forename: Karin U
authors.initials: KU
authors.lastname: Sorenmo
authors.forename: Taryn A
authors.initials: TA
authors.lastname: Donovan
authors.forename: Avenelle
authors.initials: A
authors.lastname: Turner
authors.forename: Theresa
authors.initials: T
authors.lastname: Arteaga
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Bergman
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D006394:Hemangiosarcoma / Q000473:pathology / Q000556:secondary / Q000601:surgery / Q000662:veterinary*; D008113:Liver Neoplasms / Q000556:secondary / Q000662:veterinary*; D008297:Male; D008499:Medical Records; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000473:pathology / Q000601:surgery / Q000662:veterinary*