title: [Effect of central obesity on the events of new-onset cerebral infarction among type 2 diabetes mellitus patients].
abstract: OBJECTIVE
  To analyze the effect of central obesity on new-onset cerebral infarction events among type 2 diabetes mellitus patients in the Kailuan Group.
  
  
  METHODS
  This was a prospective cohort study. In a total of 101 510 employees who had been carried out a healthy examination in Kailuan Group from Jul. 2006 to Oct. 2007. 8 306 type 2 diabetes mellitus patients were selected. According to the baseline waist measurement, the observed population was divided into two groups-with central obesity or without. The total period of follow-up was 38-53 (48.05 ± 3.09) months.
  
  
  RESULTS
  1) Mean age, BMI, the levels of SBP, DBP, pulse pressure, FPG, TC, LDL-C, uric acid significant increased in the central obesity group were higher than in the non-obese group (P < 0.01). 2) The incidence of new onset cerebral infarction in obese group was higher than that in the non-obese group (3.1% vs. 1.6%, 6.8%, P < 0.01; 3.3% vs. 1.7%, P < 0.01 in male respectively. 3) Results from the multiple logistic regression analysis showed that, compared with the non-obese group, the obese group had an increase of relative risk (RR) on new onset cerebral infarction events after adjustment on age, gender and other risk factors, with RR value as 2.07 (95%CI:1.39-3.09, P < 0.01).
  
  
  CONCLUSIONS
  Type 2 diabetes mellitus patients with central obesity seemed to have increased the risk of new-onset cerebral infarction events.
authors.affiliation: Department of Physical Examination, the Affiliated Kailuan General Hospital of Hebei Union University, Tangshan 063000, China.
authors.forename: Xiurong
authors.initials: X
authors.lastname: Liu
authors.affiliation: Department of Physical Examination, the Affiliated Kailuan General Hospital of Hebei Union University, Tangshan 063000, China.
authors.forename: Yanru
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Hospital of Zhaogezhuang, the Affiliated Kailuan General Hospital of Hebei Union University, Tangshan 063000, China.
authors.forename: Jianjun
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Physical Examination, the Affiliated Kailuan General Hospital of Hebei Union University, Tangshan 063000, China.
authors.forename: Xing
authors.initials: X
authors.lastname: Liu
authors.affiliation: Department of Physical Examination, the Affiliated Kailuan General Hospital of Hebei Union University, Tangshan 063000, China.
authors.forename: Chunwei
authors.initials: C
authors.lastname: Yang
authors.affiliation: Department of Physical Examination, the Affiliated Kailuan General Hospital of Hebei Union University, Tangshan 063000, China.
authors.forename: Junjuan
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Physical Examination, the Affiliated Kailuan General Hospital of Hebei Union University, Tangshan 063000, China.
authors.forename: Shuohua
authors.initials: S
authors.lastname: Chen
authors.affiliation: Department of Physical Examination, the Affiliated Kailuan General Hospital of Hebei Union University, Tangshan 063000, China. Email: drwusl@163.com.
authors.forename: Shouling
authors.initials: S
authors.lastname: Wu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002544:Cerebral Infarction / Q000453:epidemiology*; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D056128:Obesity, Abdominal / Q000453:epidemiology*; D011446:Prospective Studies; D012307:Risk Factors; D055815:Young Adult