title: Endometrioid adenocarcinoma in an extrauterine adenomyoma.
abstract: BACKGROUND
  Focal involvement by endometrioid adenocarcinoma in an extrauterine adenomyoma in a patient with stage 1 endometrioid adenocarcinoma presented a unique problem in staging and management of extrauterine endometrial cancer.
  
  
  METHODS
  A 49-year-old white woman, gravida 0, referred for endometrioid adenocarcinoma was found to have an extrauterine adenomyoma involved with endometrioid adenocarcinoma in the inguinal canal after surgical staging. The endometrioid adenocarcinoma involving the extrauterine adenomyoma was low-grade and noninvasive, representing an embryological anomaly transformed into endometrioid adenocarcinoma by unopposed estrogen. Stage 1A, grade 2 endometrioid adenocarcinoma was diagnosed and observed.
  
  
  CONCLUSIONS
  Stage 1 endometrioid adenocarcinoma with concurrent, noninvasive, focal involvement in an extrauterine adenomyoma represents a secondary site and does not alter disease stage.
authors.affiliation: Departments of Obstetrics and Gynecology and Pathology and Laboratory Medicine, University of Tennessee Health Science Center, and Department of Obstetrics and Gynecology, University of Tennessee Health Science Center-West Clinic, Memphis, Tennessee.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Ulm
authors.forename: David B
authors.initials: DB
authors.lastname: Robins
authors.forename: Edwin M
authors.initials: EM
authors.lastname: Thorpe
authors.forename: Mark E
authors.initials: ME
authors.lastname: Reed
mesh_terms: D000008:Abdominal Neoplasms / Q000473:pathology*; D018194:Adenomyoma / Q000473:pathology*; D018269:Carcinoma, Endometrioid / Q000473:pathology*; D016889:Endometrial Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D007264:Inguinal Canal / Q000473:pathology*; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D016609:Neoplasms, Second Primary / Q000473:pathology*