title: The diagnosis and treatment of oncocytic carcinoma.
abstract: The purpose of this study was to assess the diagnosis, treatment, and prognosis of oncocytic carcinoma. This was a retrospective study of 7 patients with oncocytic carcinoma according to the 2005 World Health Organization classification guidelines who underwent 1 or more surgical interventions within the last 20-year period from 1992 to 2012. The lesions were located in the parotid glands in 5 patients, the submandibular glands in 1 patient, and the sublingual gland in 1 patient. One of the patients experienced tumor recurrence after conservative surgery before he was admitted to our department. Five patients were treated with a total parotidectomy, and 3 underwent additional neck dissection. Only 1 patient died, as a result of pulmonary metastases. After a follow-up period of 3 to 198 months, no recurrences were found in any of the surviving patients. On the basis of our experience, poorly differentiated oncocytic carcinoma should be treated with the total resection of the affected salivary gland and a selective neck dissection. Patients with oncocytic carcinoma should remain in long-term follow-up.
authors.affiliation: From the *Department of Oral and Maxillofacial Surgery, †Central Laboratory of Stomatology, and ‡Department of Pathology, Stomatological Hospital Affiliated Medical School, Nanjing University, Nanjing, People's Republic of China.
authors.forename: Han
authors.initials: H
authors.lastname: Wei
authors.forename: Huang
authors.initials: H
authors.lastname: Xiaofeng
authors.forename: Zheng
authors.initials: Z
authors.lastname: Yang
authors.forename: Wang
authors.initials: W
authors.lastname: Zhiyong
mesh_terms: D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000175:diagnosis* / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection / Q000379:methods; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D012189:Retrospective Studies; D012468:Salivary Gland Neoplasms / Q000175:diagnosis* / Q000628:therapy*