title: Indole alkaloids from marine sources as potential leads against infectious diseases.
abstract: Indole alkaloids comprise a large and complex class of natural products found in a variety of marine sources. Infectious diseases remain a major threat to public health, and in the absence of long-term protective vaccines, the control of these infectious diseases is based on a small number of chemotherapeutic agents. Furthermore, the emerging resistance against these drugs makes it urgently necessary to discover and develop new, safe and, effective anti-infective agents. In this regard, the aim of this review is to highlight indole alkaloids from marine sources which have been shown to demonstrate activity against infectious diseases.
authors.affiliation: Institute of Chemistry and Biotechnology, Federal University of Alagoas, University City, BR 101, KM 14 Norte, Tabuleiro dos Martins, 57072-970 Maceio, AL, Brazil.
authors.forename: Paulo H B
authors.initials: PH
authors.lastname: França
authors.affiliation: School of Nursing and Pharmacy, Federal University of Alagoas, Av. Lourival de Mello Motta, S/N, Tabuleiro dos Martins, 57072-970 Maceió, AL, Brazil.
authors.forename: Daniel P
authors.initials: DP
authors.lastname: Barbosa
authors.affiliation: Institute of Chemistry and Biotechnology, Federal University of Alagoas, University City, BR 101, KM 14 Norte, Tabuleiro dos Martins, 57072-970 Maceio, AL, Brazil.
authors.forename: Daniel L
authors.initials: DL
authors.lastname: da Silva
authors.affiliation: School of Nursing and Pharmacy, Federal University of Alagoas, Av. Lourival de Mello Motta, S/N, Tabuleiro dos Martins, 57072-970 Maceió, AL, Brazil.
authors.forename: Êurica A N
authors.initials: ÊA
authors.lastname: Ribeiro
authors.affiliation: Institute of Chemistry and Biotechnology, Federal University of Alagoas, University City, BR 101, KM 14 Norte, Tabuleiro dos Martins, 57072-970 Maceio, AL, Brazil.
authors.forename: Antônio E G
authors.initials: AE
authors.lastname: Santana
authors.affiliation: Laboratory of Pharmaceutical Technology, Federal University of Paraiba, 58051-900 João Pessoa, PB, Brazil.
authors.forename: Bárbara V O
authors.initials: BV
authors.lastname: Santos
authors.affiliation: Laboratory of Pharmaceutical Technology, Federal University of Paraiba, 58051-900 João Pessoa, PB, Brazil.
authors.forename: José M
authors.initials: JM
authors.lastname: Barbosa-Filho
authors.affiliation: Department of Physiology, Federal University of Sergipe, 49000-100 São Cristóvão, SE, Brazil.
authors.forename: Jullyana S S
authors.initials: JS
authors.lastname: Quintans
authors.affiliation: Department of Physiology, Federal University of Sergipe, 49000-100 São Cristóvão, SE, Brazil.
authors.forename: Rosana S S
authors.initials: RS
authors.lastname: Barreto
authors.affiliation: Department of Physiology, Federal University of Sergipe, 49000-100 São Cristóvão, SE, Brazil.
authors.forename: Lucindo J
authors.initials: LJ
authors.lastname: Quintans-Júnior
authors.affiliation: Institute of Chemistry and Biotechnology, Federal University of Alagoas, University City, BR 101, KM 14 Norte, Tabuleiro dos Martins, 57072-970 Maceio, AL, Brazil ; School of Nursing and Pharmacy, Federal University of Alagoas, Av. Lourival de Mello Motta, S/N, Tabuleiro dos Martins, 57072-970 Maceió, AL, Brazil.
authors.forename: João X
authors.initials: JX
authors.lastname: de Araújo-Júnior
mesh_terms: D059001:Aquatic Organisms / Q000737:chemistry*; D001688:Biological Products / Q000737:chemistry* / Q000627:therapeutic use; D003141:Communicable Diseases / Q000188:drug therapy*; D006801:Humans; D026121:Indole Alkaloids / Q000737:chemistry* / Q000627:therapeutic use; D015394:Molecular Structure
chemical_list: D001688:Biological Products; D026121:Indole Alkaloids