title: Can IgA, C3, IL-6 and TNF-α act as predictors for reoccurrence of breast cancer among Iraqi women?
abstract: Blood samples were collected from 30 women with age ranged from 27-70 years after 3 cycles of chemotherapy. Sera were used for IgA, IgG, IgM, C3, C4, IL-6 and TNF-α estimation. After 3 cycles of chemotherapy, all the immunological parameters reduced except TNF-α. Patients who developed disease reoccurrence after chemotherapy exhibit a significantly higher IgA, C3, IL-6 and TNF-α levels after 3 cycles of chemotherapy than patients who did not (p < 0.05). Therefore, serum IgA, C3, IL-6 and TNF-α can be used as predictors for breast cancer reoccurrence.
authors.affiliation: College of Medicine, University of Basrah, Basrah, Iraq.
authors.forename: Nadham Kadham
authors.initials: NK
authors.lastname: Mahdi
authors.affiliation: College of Medicine, University of Basrah, Basrah, Iraq.
authors.forename: Mohammad Hussein
authors.initials: MH
authors.lastname: Al-Jowher
authors.affiliation: College of Medicine, University of Basrah, Basrah, Iraq.
authors.forename: Hiba Q
authors.initials: HQ
authors.lastname: Ali
keywords: Breast cancer; Complements; Immunoglobulines; Interleukines; Women