title: Prevalence and correlates of DSM-5 bipolar and related disorders and hyperthymic personality in the community.
abstract: BACKGROUND
  To 1) establish the lifetime and 12-month prevalence of DSM-5 bipolar and related disorders including the new algorithmically defined conditions grouped within Other Specified Bipolar and Related Disorders (OSBARD) as well as hyperthymic personality in a randomly selected community sample, and 2) determine the clinical relevance of the OSBARD category in terms of sociodemographic characteristics, course, comorbidity and treatment patterns by comparing the subjects of this category to those with bipolar-I (BP-I), bipolar-II (BP-II), major depressive disorder (MDD), and those with no history of mood disorders.
  
  
  METHODS
  The semi-structured Diagnostic Interview for Genetic Studies was administered by masterslevel psychologists to a random sample of an urban area (n=3'719).
  
  
  RESULTS
  The lifetime prevalence was 1.0% for BP-I, 0.8% for BP-II, 1.0% for OSBARD and 3% for hyperthymic personality. Subjects with OSBARD were more severely affected than subjects without a history of mood disorders regarding almost all clinical correlates. Compared to those with MDD, they also revealed an elevated risk of suicidal attempts, lower global functioning, more treatment seeking and more lifetime comorbidity including anxiety, substance use and impulse-control disorders. However, they did not differ from subjects with BP-II.
  
  
  CONCLUSIONS
  Small sample sizes for bipolar and related disorders and potential inaccurate recall of symptoms.
  
  
  CONCLUSIONS
  The modifications of diagnostic criteria for manic/hypomanic episodes according to the DSM-5 only marginally affect the prevalence estimates for BP-I and BP-II. The new DSM-5 OSBARD category is associated with significant clinical burden, is hardly distinct from BP-II with respect to clinical correlates and deserves similar clinical attention.
authors.affiliation: Department of Psychiatry, CHUV, Lausanne, Switzerland. Electronic address: sylfa.fassassi@chuv.ch.
authors.forename: Sylfa
authors.initials: S
authors.lastname: Fassassi
authors.affiliation: Department of Psychiatry, CHUV, Lausanne, Switzerland.
authors.forename: Caroline
authors.initials: C
authors.lastname: Vandeleur
authors.affiliation: Department of Mental Health and Psychiatry, Geneva University, Switzerland.
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Aubry
authors.affiliation: Department of Psychiatry, CHUV, Lausanne, Switzerland.
authors.forename: Enrique
authors.initials: E
authors.lastname: Castelao
authors.affiliation: Department of Psychiatry, CHUV, Lausanne, Switzerland.
authors.forename: Martin
authors.initials: M
authors.lastname: Preisig
mesh_terms: D000328:Adult; D000368:Aged; D001008:Anxiety Disorders / Q000175:diagnosis / Q000453:epidemiology*; D001714:Bipolar Disorder / Q000175:diagnosis / Q000453:epidemiology*; D015897:Comorbidity; D003527:Cyclothymic Disorder / Q000175:diagnosis / Q000453:epidemiology*; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D007174:Disruptive, Impulse Control, and Conduct Disorders / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007406:Interview, Psychological; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012494:Sampling Studies; D019966:Substance-Related Disorders / Q000175:diagnosis / Q000453:epidemiology*; D013557:Switzerland / Q000453:epidemiology; D014505:Urban Population / Q000706:statistics & numerical data
keywords: Bipolar disorders; Bipolar related disorders; Bipolar spectrum; Course; Hyperthymic personality; Prevalence