title: The role of the γ δ T cell in allergic diseases.
abstract: The predominant distribution of γ δ T cells in the mucosal and epithelial tissues makes these unconventional lymphocytes the "guards" to contact external environment (like allergens) and to contribute to immune surveillance, as well as "vanguards" to participate in initiating mucosal inflammation. Therefore, γ δ T cells have been considered to bridge the innate and adaptive immunity. The role these cells play in allergy seems to be complicated and meaningful, so it makes sense to review the characteristics and role of γ δ T cells in allergic diseases.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, The Third Affiliated Hospital, SUN Yat-sen University, Guangzhou 510630, China.
authors.forename: Rui
authors.identifier: 0000-0001-8693-4717
authors.initials: R
authors.lastname: Zheng
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, The Third Affiliated Hospital, SUN Yat-sen University, Guangzhou 510630, China.
authors.forename: Qintai
authors.initials: Q
authors.lastname: Yang
mesh_terms: D000367:Age Factors; D000485:Allergens / Q000276:immunology; D000818:Animals; D016207:Cytokines / Q000096:biosynthesis; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology* / Q000378:metabolism* / Q000517:prevention & control / Q000628:therapy; D056747:Immunomodulation; D008297:Male; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000378:metabolism*; D012737:Sex Factors; D016176:T-Lymphocyte Subsets / Q000276:immunology* / Q000378:metabolism*
chemical_list: D000485:Allergens; D016207:Cytokines; D016692:Receptors, Antigen, T-Cell, gamma-delta