title: Single molecule analysis by biological nanopore sensors.
abstract: Nanopore sensors provide a highly innovative technique for a rapid and label-free single molecule analysis, which holds a great potential in routing applications. Biological nanopores have been used as ultra-sensitive sensors over a wide range of single molecule analysis including DNA sequencing, disease diagnosis, drug screening, environment monitoring and the construction of molecule machines. This mini review will focus on the current strategies for the identification and characterization of an individual analyte, especially based on our recent achievements in biological nanopore biosensors.
authors.affiliation: Key Laboratory for Advanced Materials & Department of Chemistry, East China University of Science and Technology, P. R. China. ytlong@ecust.edu.cn.
authors.forename: Yi-Lun
authors.initials: YL
authors.lastname: Ying
authors.forename: Chan
authors.initials: C
authors.lastname: Cao
authors.forename: Yi-Tao
authors.initials: YT
authors.lastname: Long
mesh_terms: D000818:Animals; D052157:Aptamers, Nucleotide / Q000737:chemistry; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D008958:Models, Molecular; D058608:Nanopores / Q000648:ultrastructure
chemical_list: D052157:Aptamers, Nucleotide