title: Evaluation and comparison of anti-Candida effect of heat cure polymethylmethacrylate resin enforced with silver nanoparticles and conventional heat cure resins: an in vitro study.
abstract: Recent years have been dominated by research in nano science. Dentistry is no exception and there is increased research on nanoparticles in dentistry. Complete dentures increase the carriage of Candida in healthy patients, and the proliferation of C. albicans can be associated with denture-induced stomatitis.
  
  
  OBJECTIVE
  To evaluate the anti-Candida effect of heat cure denture base resins reinforced with Ag° in the ratio of 4:1, 3:1, 2:1 (Groups B, C, and D, respectively) to the weight of denture base resins.
  
  
  METHODS
  Ag° were synthesized by chemical reduction method, incorporated into the polymer powder according to the ratio for each group, subjected to polymerization and microbial assay was calculated for the reference C. albicans strains by agar diffusion method for the incubation period of 24 h.
  
  
  RESULTS
  Group D showed multifold decrease in the colony-forming units.
  
  
  CONCLUSIONS
  The antimicrobial effect of silver could be used vividly in the denture base for immunocompromised and geriatric patients.
authors.affiliation: Department of Prosthodontics, Sri Ramasamy Memorial Dental College, Ramapuram, Chennai, Tamil Nadu, India.
authors.forename: S
authors.initials: S
authors.lastname: Suganya
authors.forename: S C
authors.initials: SC
authors.lastname: Ahila
authors.forename: B Muthu
authors.initials: BM
authors.lastname: Kumar
authors.forename: M Vasantha
authors.initials: MV
authors.lastname: Kumar
mesh_terms: D002175:Candida / Q000187:drug effects* / Q000254:growth & development; D006358:Hot Temperature; D066298:In Vitro Techniques; D053768:Metal Nanoparticles; D019904:Polymethyl Methacrylate / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*
chemical_list: D012834:Silver; D019904:Polymethyl Methacrylate