title: [Ocular surface squamous neoplasia: analysis of 34 cases].
abstract: OBJECTIVE
  To evaluate location, treatment and clinical course in cases of ocular surface squamous neoplasia (OSSN).
  
  
  METHODS
  Thirty-four cases with OSSN [conjunctival intraepithelial neoplasia (CIN) 17 cases; squamous cell carcinoma (SCC) 17 cases] treated in Kyushu University hospital from 2000 to 2011 were retrospectively studied.
  
  
  RESULTS
  Lesions of CIN were observed in the conjunctiva bulbar in sixteen cases (16/17), and in eleven of those, the lesions were seen in the nasal part (nasal : lateral = 11 : 6). The lesions of eight SCC cases (8/17) were observed in the conjunctiva bulbar, of seven cases (7/17) were observed in the conjunctiva palpebral, and of two cases (2/17) in the fornical conjunctiva. Significantly far more cases of SCC in the conjunctiva bulbar were seen in the nasal part compared to the lateral part (nasal : lateral = 7 : 1). Most SCC lesions in the conjunctiva palpebral and fornix were observed in the upper eyelid (upper : lower = 6 : 3). CIN were treated by excision in nine cases (9/17), excision after topical chemotherapy in three cases (3/ 17), and topical chemotherapy in 5 cases (5/17). Nine SCC patients were treated by excision (9/17), four by excision after topical chemotherapy (4/17), and four by radiotherapy (4/17). Three cases of CIN and one case of SCC had recurrence and needed further treatment.
  
  
  CONCLUSIONS
  The use of preoperative chemotherapy and radiotherapy for OSSN patients seems useful for a good outcome.
authors.forename: Mika
authors.initials: M
authors.lastname: Tanabe
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yoshikawa
authors.forename: Yoko
authors.initials: Y
authors.lastname: Onishi
authors.forename: Ri-ichiro
authors.initials: R
authors.lastname: Kohno
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Ishibashi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002278:Carcinoma in Situ / Q000473:pathology* / Q000628:therapy*; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000628:therapy*; D003230:Conjunctival Neoplasms / Q000473:pathology* / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged