title: [A double-blind RCT of the hemostatic effects of local packing of Nasopore combined with hemocoagulase injection for postoperative management of FESS].
abstract: OBJECTIVE
  To compare the hemostatic effects of local packing of Nasopore combined with hemocoagulase injection and local packing of Nasopore combined with saline injection for postoperative management of functional endoscopic sinus surgery by a double-blind, randomized control clinical trial.
  
  
  METHODS
  Sixty-eight cases of chronic sinusitis needed functional endoscopic sinus surgery were randomly divided into the experimental group of 40 cases and control group of 28 cases, respectively. For the experimental group, 1 U of hemocoagulase dissolved in 0.5 ml saline was injected into Nasopore which was packed into the nasal cavity after operation. For the control group, 0.5 ml of saline was injected. The postoperative bleeding of the two groups were scored by visual analogue scale.
  
  
  RESULTS
  There was statistically significant difference between the bleeding VAS scores assessed 6 hours and the ones assessed 1, 2 and 3 days after the operation in the control group (P < 0.05). There was the statistically significant difference between the bleeding VAS scores of experimental group and control group assessed 6 h after the operation (P < 0.05).
  
  
  CONCLUSIONS
  The hemocoagulase may improve the hemostatic effect of Nasopore 6 hours after the operation by combined injection with Nasopore as nasal cavity packing.
authors.forename: Jia
authors.initials: J
authors.lastname: Ren
authors.forename: Yilin
authors.initials: Y
authors.lastname: Liu
authors.forename: Qiulin
authors.initials: Q
authors.lastname: Li
authors.forename: Feng
authors.initials: F
authors.lastname: Liu
authors.forename: Junming
authors.initials: J
authors.lastname: Xian
authors.forename: Huimin
authors.initials: H
authors.lastname: An
authors.forename: Yafeng
authors.initials: Y
authors.lastname: Liu
authors.forename: Shixi
authors.initials: S
authors.lastname: Liu
mesh_terms: D001458:Bandages; D012103:Batroxobin / Q000008:administration & dosage*; D004311:Double-Blind Method; D004724:Endoscopy; D004844:Epistaxis / Q000628:therapy*; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D009296:Nasal Cavity / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D012103:Batroxobin