title: Xp 11.2 translocation renal carcinoma in young adults; recently classified distinct subtype.
abstract: BACKGROUND
  XP11.2 renal translocation carcinomas are often encountered in paediatric group of patients where they are believed to be rather indolent. They are rare but more aggressive in young adults. They are slow growing, sometimes without characteristic symptoms and their biologic behaviour is uncertain.
  
  
  METHODS
  We report two cases of this type of tumour in Slovenian young adult males with long and unusual history. Tumours were confirmed imunohistologically by positive reaction for CD10, P504S and TFE3.
  
  
  CONCLUSIONS
  According to the indications in the literature prognosis of these tumours in young adults depends upon the stage. It seems that cysts, haematomas and necrosis around the kidney are often encountered in these tumours. In advanced stage with lymph nodes involvement or distant metastases, the prognosis is poor. Surgery seems to be basic mode of therapy.
authors.affiliation: Urologic Clinical Department, University Medical Centre Ljubljana, Ljubljana, Slovenia.
authors.forename: Andrej
authors.initials: A
authors.lastname: Kmetec
authors.affiliation: Institute of Pathology, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia.
authors.forename: Jera
authors.initials: J
authors.lastname: Jeruc
keywords: histology; renal tumours; translocation renal cell carcinoma