title: NSAIDs and bleeding in periodontal surgery.
abstract: OBJECTIVE
  To evaluate and compare the clinical effects of ibuprofen and diclofenac sodium on bleeding during periodontal surgery.
  
  
  METHODS
  Thirteen medically healthy men and women of mean age 37.5±17.67 (mean age± standard deviation) were selected for the study. All the subjects were divided into three groups: control (C) and test groups (T1) and (T2). Each subject of T1 group and T2 group was given ibuprofen and diclofenac sodium respectively, prior to surgery. Bleeding times of patients were recorded prior to performance of periodontal flap surgical procedures.
  
  
  RESULTS
  It was found that there was increased bleeding time and increased peri-operative bleeding when ibuprofen and diclofenac sodium were taken prior to surgery and this was statistically significant. (2.5538 (T1), 1.8385 (T2) versus 1.2385 (C) minute, p= .001) (mean blood loss) and (62.0325 ± 9.0594 (T1), 51.082 ± 9.792 (T2) versus 37.4992 ± 5.99 (C) millilitre, p = .000).
  
  
  CONCLUSIONS
  The findings of this study suggested that pre-operative administration of ibuprofen and diclofenac sodium could increase bleeding time and peri - operative blood loss.
authors.affiliation: Senior Lecturer, Department of Periodontics, Dr. D.Y. Patil Dental College & Hospital , Nerul, Navi Mumbai, India .
authors.forename: Sanyuktha
authors.initials: S
authors.lastname: Shetty
authors.affiliation: Professor and Head, Department of Periodontics, Srinivas Institute of Dental Sciences , Mukka, Karnataka, India .
authors.forename: Sharath
authors.initials: S
authors.lastname: K
authors.affiliation: Professor and Head, Department of Periodontics, A.B. Shetty Memorial Institute of Dental Sciences , Deralakatte, Mangalore, Karnataka, India .
authors.forename: Biju
authors.initials: B
authors.lastname: Thomas
authors.affiliation: Senior Lecturer, Department of Prosthodontics, Dr. D.Y. Patil Dental College & Hospital , Nerul, Navi Mumbai, India .
authors.forename: Nitin
authors.initials: N
authors.lastname: Shetty
authors.affiliation: Professor and Head, Department of Periodontics, Dr. D.Y. Patil Dental College & Hospital , Nerul, Navi Mumbai, India .
authors.forename: Arvind
authors.initials: A
authors.lastname: Shetty
authors.affiliation: Professor, Department of Periodontics, Dr. D.Y. Patil Dental College & Hospital , Nerul, Navi Mumbai, India .
authors.forename: Devanand
authors.initials: D
authors.lastname: Shetty
keywords: Blood loss; Diclofenac sodium; Ibuprofen; Periodontal flap surgery