title: Infliximab-induced aseptic meningitis.
abstract: Infliximab is a commonly used biologic agent in the treatment of various autoimmune diseases. Although it is generally well tolerated in most patients, infliximab has been associated with some rare but serious adverse events. Aseptic meningitis is one such distinctly uncommon side effect. We present the case of middle-aged white patient, who presented with fever and headache within a few days of starting the infliximab therapy and was diagnosed with infliximab-induced aseptic meningitis after a complete workup. To our knowledge, this is the fifth case of infliximab-induced aseptic meningitis reported in literature. Because of atypical presentation, the diagnosis can be easily missed. It is vital to increase awareness of this potentially severe side effect among internists and community physicians.
authors.affiliation: SUNY Upstate Medical University, 50 Presidential Plaza, Syracuse, NY 13202. Electronic address: rushishah.17@gmail.com.
authors.forename: Rushikesh
authors.initials: R
authors.lastname: Shah
authors.affiliation: 50 Presidential Plaza, Syracuse, NY 13202. Electronic address: Milisshah5@gmail.com.
authors.forename: Mili
authors.initials: M
authors.lastname: Shah
authors.affiliation: SUNY Upstate Medical University, 750 E Adams St, Syaracuse, NY 13210. Electronic address: bansalN@upstate.edu.
authors.forename: Nidhi
authors.initials: N
authors.lastname: Bansal
authors.affiliation: SUNY Upstate Medical University, 750 E Adams St, Syaracuse, NY 13210. Electronic address: manochaD@upstate.edu.
authors.forename: Divey
authors.initials: D
authors.lastname: Manocha
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000627:therapeutic use; D000911:Antibodies, Monoclonal / Q000009:adverse effects* / Q000627:therapeutic use; D003424:Crohn Disease / Q000188:drug therapy; D004636:Emergency Service, Hospital; D006801:Humans; D000069285:Infliximab; D008297:Male; D008582:Meningitis, Aseptic / Q000139:chemically induced*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000911:Antibodies, Monoclonal; D000069285:Infliximab