title: Anti-fungal activity of Morinda citrifolia (noni) extracts against Candida albicans: an in vitro study.
abstract: OBJECTIVE
  The aim of this study was to investigate the anti-fungal activity of Morinda citrifolia fruit extract on Candida albicans.
  
  
  METHODS
  Juice extract from M. citrifolia fruit was lyophilized and used in anti-fungal testing. Anti-fungal activity of M. citrifolia fruit extract against C. albicans was tested in vitro at various concentrations. The inhibitory effect of M. citrifolia extract on C. albicans was determined by agar culture and applied broth dilution test.
  
  
  RESULTS
  M. citrifolia extract at 1000 μg/ml concentration effectively inhibited the growth of C. albicans (16.6 ± 0.3) compared with the positive control - amphotericin B (20.6 ± 0.6). It was found to be a dose-dependent reaction.
  
  
  CONCLUSIONS
  M. citrifolia fruit extract had an anti-fungal effect on C. albicans and the inhibitory effect varied with concentration.
authors.affiliation: Department of Public Health Dentistry, SRM Dental College, Ramapuram, Chennai, Tamil Nadu, India.
authors.forename: K
authors.initials: K
authors.lastname: Barani
authors.forename: Sunayana
authors.initials: S
authors.lastname: Manipal
authors.forename: D
authors.initials: D
authors.lastname: Prabu
authors.forename: Adil
authors.initials: A
authors.lastname: Ahmed
authors.forename: Preethi
authors.initials: P
authors.lastname: Adusumilli
authors.forename: C
authors.initials: C
authors.lastname: Jeevika
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects*; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests; D032066:Morinda / Q000737:chemistry*; D010936:Plant Extracts / Q000494:pharmacology*
chemical_list: D000935:Antifungal Agents; D010936:Plant Extracts