title: Serum adenosine deaminase activity in cutaneous anthrax.
abstract: BACKGROUND
  Adenosine deaminase (ADA) activity has been discovered in several inflammatory conditions; however, there are no data associated with cutaneous anthrax. The aim of this study was to investigate serum ADA activity in patients with cutaneous anthrax.
  
  
  METHODS
  Sixteen patients with cutaneous anthrax and 17 healthy controls were enrolled. We measured ADA activity; peripheral blood leukocyte, lymphocyte, neutrophil, and monocyte counts; erythrocyte sedimentation rate; and C reactive protein levels.
  
  
  RESULTS
  Serum ADA activity was signiﬁcantly higher in patients with cutaneous anthrax than in the controls (p<0.001). A positive correlation was observed between ADA activity and lymphocyte counts (r=0.589, p=0.021) in the patient group.
  
  
  CONCLUSIONS
  This study suggests that serum ADA could be used as a biochemical marker in cutaneous anthrax.
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey.
authors.forename: Mahmut
authors.initials: M
authors.lastname: Sunnetcioglu
authors.affiliation: Department of Emergency Medicine, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey.
authors.forename: Sevdegul
authors.initials: S
authors.lastname: Karadas
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Aslan
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey.
authors.forename: Mehmet Resat
authors.initials: MR
authors.lastname: Ceylan
authors.affiliation: Department of Chemistry, Yuzuncu Yil University, Faculty of Science and Art, Van, Turkey.
authors.forename: Halit
authors.initials: H
authors.lastname: Demir
authors.affiliation: Department of Emergency Medicine, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey.
authors.forename: Mehmet Resit
authors.initials: MR
authors.lastname: Oncu
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey.
authors.forename: Mustafa Kasım
authors.initials: MK
authors.lastname: Karahocagil
authors.affiliation: Department of Pulmonary Diseases, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey.
authors.forename: Aysel
authors.initials: A
authors.lastname: Sunnetcioglu
authors.affiliation: Department of Family Medicine, Dıskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.
authors.forename: Cenk
authors.initials: C
authors.lastname: Aypak
mesh_terms: D000243:Adenosine Deaminase / Q000097:blood*; D000328:Adult; D000881:Anthrax / Q000097:blood* / Q000201:enzymology*; D016022:Case-Control Studies; D003710:Demography; D005260:Female; D006801:Humans; D008297:Male; D017192:Skin Diseases, Bacterial / Q000097:blood* / Q000201:enzymology*
chemical_list: C548482:ADA protein, human; D000243:Adenosine Deaminase