title: [AA Amyloidosis].
abstract: AA amyloidosis is caused by the tissue deposition of AA protein, which is degraded from serum amyloid A (SAA) mainly produced in an inflammatory state. However, AA amyloidosis is hardly observed in neurol-cerebral diseases. Therefore, in this issue, the role of cytokines and activation of signal transducer and activator of transcription 3 (STAT3) in SAA-inducing mechanism are presented.
authors.affiliation: Immuno-Medical Science Division of Applied Chemistry, Graduate School of Engineering, Osaka University.
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Yoshizaki
mesh_terms: D000686:Amyloidosis / Q000276:immunology / Q000378:metabolism*; D006801:Humans; D015850:Interleukin-6 / Q000096:biosynthesis / Q000276:immunology; D011485:Protein Binding; D050796:STAT3 Transcription Factor / Q000378:metabolism; D000685:Serum Amyloid A Protein / Q000378:metabolism*; D014158:Transcription, Genetic
chemical_list: D015850:Interleukin-6; D050796:STAT3 Transcription Factor; D000685:Serum Amyloid A Protein