title: Effects of Electroacupuncture on Facial Nerve Function and HSV-1 DNA Quantity in HSV-1 Induced Facial Nerve Palsy Mice.
abstract: Acupuncture is a common and effective therapeutic method to treat facial nerve palsy (FNP). However, its underlying mechanism remains unclear. This study was aimed to investigate the effects of electroacupuncture on symptoms and content of HSV-1 DNA in FNP mice. Mice were randomized into four groups, an electroacupuncture treatment group, saline group, model animal group, and blank control group. Electroacupuncture was applied at Jiache (ST6) and Hegu (LI4) in electroacupuncture group once daily for 14 days, while electroacupuncture was not applied in model animal group. In electroacupuncture group, mice recovered more rapidly and HSV-1 DNA content also decreased more rapidly, compared with model animal group. We conclude that electroacupuncture is effective to alleviate symptoms and promote the reduction of HSV-1 in FNP.
authors.affiliation: Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.
authors.forename: Hongzhi
authors.initials: H
authors.lastname: Tang
authors.affiliation: Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.
authors.forename: Shuwei
authors.initials: S
authors.lastname: Feng
authors.affiliation: Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.
authors.forename: Jiao
authors.initials: J
authors.lastname: Chen
authors.affiliation: Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.
authors.forename: Jie
authors.identifier: 0000-0002-6787-0938
authors.initials: J
authors.lastname: Yang
authors.affiliation: Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.
authors.forename: Mingxiao
authors.initials: M
authors.lastname: Yang
authors.affiliation: Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, Sichuan 610072, China.
authors.forename: Zhendong
authors.initials: Z
authors.lastname: Zhong
authors.affiliation: Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Li
authors.affiliation: Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.
authors.forename: Fanrong
authors.initials: F
authors.lastname: Liang