title: Uterine perivascular epithelioid cell neoplasms (PEComas): report of two cases and literature review.
abstract: Perivascular epithelioid cell tumors (PEComas) are rare tumors characterized by co-expression of melanocytic and smooth muscle markers. PEComas have been reported in a wide variety of anatomic sites. In the female genital tract, PEComas most frequently affect the uterus. PEComas which occur in non-classic anatomic distributions are known as perivascular epithelioid cell tumor-not otherwise specified (PEComa-NOS). PEComas have an unpredictable biologic behavior, with some tumors being unresectable or metastatic at the time of diagnosis. The risk of aggressive behavior of these tumors has been linked to a number of factors evaluable on histopathological review following initial surgical resection. The authors report two cases of PEComa-NOS of the uterus: one with disease confined to uterus and the other case with lung and liver metastasis.
authors.forename: A
authors.initials: A
authors.lastname: Cossu
authors.forename: P
authors.initials: P
authors.lastname: Paliogiannis
authors.forename: F
authors.initials: F
authors.lastname: Tanda
authors.forename: S
authors.initials: S
authors.lastname: Dessole
authors.forename: G
authors.initials: G
authors.lastname: Palmieri
authors.forename: G
authors.initials: G
authors.lastname: Capobianco
mesh_terms: D005260:Female; D006801:Humans; D008875:Middle Aged; D054973:Perivascular Epithelioid Cell Neoplasms / Q000473:pathology*; D014594:Uterine Neoplasms / Q000473:pathology*