title: Lichenoid drug reaction to isoniazid presenting as exfoliative dermatitis in a patient with acquired immunodeficiency syndrome.
abstract: Human immunodeficiency virus-infected patients are at increased risk of drug reactions because of immune dysregulation and multiple drug intake. Lichenoid drug reactions to isoniazid have been reported previously in the literature. However, for lichenoid drug reaction to isoniazid to be so extensive to present as exfoliative dermatitis is rare. We report here a rare case of lichenoid drug reaction to isoniazid presenting as exfoliative dermatitis in a patient with acquired immunodeficiency syndrome.
authors.affiliation: Department of Dermatology and STD, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, India binod.k.thakur@gmail.com.
authors.forename: B K
authors.initials: BK
authors.lastname: Thakur
authors.affiliation: Department of Dermatology and STD, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, India.
authors.forename: S
authors.initials: S
authors.lastname: Verma
authors.affiliation: Department of Pathology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, India.
authors.forename: J
authors.initials: J
authors.lastname: Mishra
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000328:Adult; D000995:Antitubercular Agents / Q000009:adverse effects*; D003873:Dermatitis, Exfoliative / Q000139:chemically induced*; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology*; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007538:Isoniazid / Q000009:adverse effects*; D017512:Lichenoid Eruptions / Q000139:chemically induced*; D008297:Male; D010328:Patch Tests; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents; D007538:Isoniazid
keywords: AIDS; HIV; adverse drug reaction; antibiotics; antiretroviral therapy; drug rash; exfoliative dermatitis; isoniazid; lichenoid