title: Evaluation of an immunochromatographic point-of-care test for the simultaneous detection of nontreponemal and treponemal antibodies in patients with syphilis.
abstract: We described the evaluation of the Syphilis Screening & Confirm Assay for the simultaneous detection of nontreponemal and treponemal antibodies. A total of 248 samples were evaluated. The sensitivity of the tests was 98.8%, 99.5% and 98.9%, while specificity was 94.7%, 88.9% and 93.2%, respectively, as compared with the rapid plasma reagin, Treponema pallidum hemagglutination assay, and fluorescent treponemal antibody absorption tests.
authors.affiliation: From the *Clin Path-Unidade de Microbiologia Médica/Instituto de Higiene e Medicina Tropical, Lisboa, Portugal; Centro de Recursos Microbiológicos (CREM), Lisboa, Portugal; and †Chemical Engineering-§Unidade de Microbiologia Médica/Instituto de Higiene e Medicina Tropical, Lisboa, Portugal.
authors.forename: Rita
authors.initials: R
authors.lastname: Castro
authors.forename: Ângela
authors.initials: Â
authors.lastname: Lopes
authors.forename: Filomena
authors.initials: F
authors.lastname: da Luz Martins Pereira
mesh_terms: D000907:Antibodies, Bacterial / Q000097:blood*; D002846:Chromatography, Affinity; D037001:Directive Counseling; D005260:Female; D016508:Fluorescent Treponemal Antibody-Absorption Test; D006801:Humans; D008297:Male; D008403:Mass Screening; D019095:Point-of-Care Systems; D012680:Sensitivity and Specificity; D013587:Syphilis / Q000097:blood / Q000276:immunology* / Q000517:prevention & control; D013588:Syphilis Serodiagnosis / Q000379:methods*; D014210:Treponema pallidum / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial