title: Electrochemiluminescent swimmers for dynamic enzymatic sensing.
abstract: An electrochemiluminescent (ECL) swimmer driven by bipolar electrochemistry is reported for enzymatic glucose sensing. The chemo-mechanical motion is induced by localized hydrogen bubble generation. The concomitant oxidation of the luminophore and of the enzymatically-produced NADH leads to ECL emission with a direct glucose-dependent light intensity. We demonstrate herein the local sensing and reporting of glucose in a concentration gradient explored by the ECL swimmer. Such a dynamic sensing approach combines in a synergetic way the wireless propulsion with the enzymatic selectivity using ECL as a readout method at the level of moving objects.
authors.affiliation: Univ. Bordeaux, ISM, UMR 5255, F-33400 Talence, France. Laurent.Bouffier@enscbp.fr Neso.Sojic@enscbp.fr.
authors.forename: Milica
authors.initials: M
authors.lastname: Sentic
authors.forename: Stéphane
authors.initials: S
authors.lastname: Arbault
authors.forename: Bertrand
authors.initials: B
authors.lastname: Goudeau
authors.forename: Dragan
authors.initials: D
authors.lastname: Manojlovic
authors.forename: Alexander
authors.initials: A
authors.lastname: Kuhn
authors.forename: Laurent
authors.initials: L
authors.lastname: Bouffier
authors.forename: Neso
authors.initials: N
authors.lastname: Sojic
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D055664:Electrochemical Techniques / Q000379:methods*; D057075:Enzyme Assays / Q000379:methods; D005947:Glucose / Q000032:analysis / Q000737:chemistry; D008163:Luminescent Measurements / Q000379:methods*; D017433:Protein Structure, Secondary
chemical_list: D005947:Glucose