title: Gold-catalyzed [1,5]-hydride shift onto unactivated alkynes to trigger an intermolecular Diels-Alder reaction.
abstract: A [1,5]-hydride shift of sp(3) C-H onto an unactivated carbon-carbon triple bond catalyzed by a gold(I) complex enabled N-propargylisoindolines to be latent dienes and therefore triggered an intermolecular Diels-Alder reaction with dienophiles. This protocol provides an atom-economical and straightforward approach to access a wide range of polycyclic skeletons in high yields and with excellent diastereoselectivities from easily accessible molecules.
authors.affiliation: Hefei National Laboratory for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China , Hefei 230026, China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Wu
authors.forename: Shu-Sen
authors.initials: SS
authors.lastname: Chen
authors.forename: Yue
authors.initials: Y
authors.lastname: Hu
authors.forename: Liu-Zhu
authors.initials: LZ
authors.lastname: Gong