title: Effect of the 2010 task force criteria on reclassification of cardiovascular magnetic resonance criteria for arrhythmogenic right ventricular cardiomyopathy.
abstract: BACKGROUND
  We sought to evaluate the effect of application of the revised 2010 Task Force Criteria (TFC) on the prevalence of major and minor Cardiovascular Magnetic Resonance (CMR) criteria for Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) versus application of the original 1994 TFC. We also assessed the utility of MRI to identify alternative diagnoses for patients referred for ARVC evaluation.
  
  
  METHODS
  968 consecutive patients referred to our institution for CMR with clinical suspicion of ARVC from 1995 to 2010, were evaluated for the presence of major and minor CMR criteria per the 1994 and 2010 ARVC TFC. CMR criteria included right ventricle (RV) dilatation, reduced RV ejection fraction, RV aneurysm, or regional RV wall motion abnormalities. When quantitative measures of RV size and function were not available, and in whom abnormal size or function was reported, a repeat quantitative analysis by 2 qualified CMR physicians in consensus.
  
  
  RESULTS
  Of 968 patients, 220 (22.7%) fulfilled either a major or a minor 1994 TFC, and 25 (2.6%) fulfilled any of the 2010 TFC criterion. Among patients meeting any 1994 criteria, only 25 (11.4%) met at least one 2010 criterion. All patients who fulfilled a 2010 criteria also satisfied at least one 1994 criterion. Per the 2010 TFC, 21 (2.2%) patients met major criteria and 4 (0.4%) patients fulfilled at least one minor criterion. Eight patients meeting 1994 minor criteria were reclassified as satisfying 2010 major criteria, while 4 patients fulfilling 1994 major criteria were reclassified to only minor or no criteria under the 2010 TFC.Eighty-nine (9.2%) patients had alternative cardiac diagnoses, including 43 (4.4%) with clinically significant potential ARVC mimics. These included cardiac sarcoidosis, RV volume overload conditions, and other cardiomyopathies.
  
  
  CONCLUSIONS
  Application of the 2010 TFC resulted in reduction of total patients meeting any diagnostic CMR criteria for ARVC from 22.7% to 2.6% versus the 1994 TFC. CMR identified alternative cardiac diagnoses in 9.2% of patients, and 4.4% of the diagnoses were potential mimics of ARVC.
authors.affiliation: Department of Radiology, The First Affiliated Hospital of China Medical University, Shenyang, China. tingliu365@gmail.com.
authors.forename: Ting
authors.initials: T
authors.lastname: Liu
authors.forename: Amit
authors.initials: A
authors.lastname: Pursnani
authors.forename: Umesh C
authors.initials: UC
authors.lastname: Sharma
authors.forename: Yongkasem
authors.initials: Y
authors.lastname: Vorasettakarnkij
authors.forename: Daniel
authors.initials: D
authors.lastname: Verdini
authors.forename: Peerawut
authors.initials: P
authors.lastname: Deeprasertkul
authors.forename: Ashley M
authors.initials: AM
authors.lastname: Lee
authors.forename: Heidi
authors.initials: H
authors.lastname: Lumish
authors.forename: Manavjot S
authors.initials: MS
authors.lastname: Sidhu
authors.forename: Hector
authors.initials: H
authors.lastname: Medina
authors.forename: Stephan
authors.initials: S
authors.lastname: Danik
authors.forename: Suhny
authors.initials: S
authors.lastname: Abbara
authors.forename: Godtfred
authors.initials: G
authors.lastname: Holmvang
authors.forename: Udo
authors.initials: U
authors.lastname: Hoffmann
authors.forename: Brian B
authors.initials: BB
authors.lastname: Ghoshhajra
mesh_terms: D000328:Adult; D019571:Arrhythmogenic Right Ventricular Dysplasia / Q000145:classification / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology / Q000503:physiopathology; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D019983:Guideline Adherence; D006352:Heart Ventricles / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D017380:Hypertrophy, Right Ventricular / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000592:standards*; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D009206:Myocardium / Q000473:pathology*; D017410:Practice Guidelines as Topic; D011237:Predictive Value of Tests; D015995:Prevalence; D012189:Retrospective Studies; D013318:Stroke Volume; D018497:Ventricular Dysfunction, Right / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D016278:Ventricular Function, Right
chemical_list: D003287:Contrast Media