title: Gender disparities in ocular inflammatory disorders.
abstract: Ocular inflammatory disorders disproportionately affect women, and the majority of affected women are of childbearing age. The role of sex or reproductive hormones has been proposed in many other inflammatory or autoimmune disorders, and findings from non-ocular autoimmune diseases suggest a complex interaction between sex hormones, genetic factors and the immune system. However, despite the age and sex bias, factors that influence this disparity are complicated and unclear. This review aims to evaluate the gender disparities in prevalence, incidence and severity of the most common infectious and non-infectious ocular inflammatory disorders.
authors.affiliation: National Eye Institute, National Institutes of Health , Bethesda, MD , USA .
authors.forename: Hatice Nida
authors.initials: HN
authors.lastname: Sen
authors.forename: Janet
authors.initials: J
authors.lastname: Davis
authors.forename: Didar
authors.initials: D
authors.lastname: Ucar
authors.forename: Austin
authors.initials: A
authors.lastname: Fox
authors.forename: Chi Chao
authors.initials: CC
authors.lastname: Chan
authors.forename: Debra A
authors.initials: DA
authors.lastname: Goldstein
mesh_terms: D001327:Autoimmune Diseases / Q000453:epidemiology*; D005260:Female; D020022:Genetic Predisposition to Disease; D012739:Gonadal Steroid Hormones / Q000502:physiology; D054624:Health Status Disparities; D006801:Humans; D007107:Immune System / Q000502:physiology; D008297:Male; D012737:Sex Factors; D014605:Uveitis / Q000453:epidemiology*
chemical_list: D012739:Gonadal Steroid Hormones
keywords: Disparity; gender; ocular inflammation; sex; uveitis