title: [Linear insertion of atrioventricular valves in children with and without Down's syndrome].
abstract: OBJECTIVE
  Study various parameters encountered in the linear insertion of the atrioventricular valves (LIAVV) in patients with and without Down's syndrome (DS).
  
  
  METHODS
  A group of patients (n = 6240) aged from 0 to 16 years with and without congenital heart disease (CHD) registered over 6 years (1.07.2005-30.06.2011) in the National Registry of the Pediatric and Congenital Heart Disease of the Society of Cardiology in Lebanon.
  
  
  METHODS
  Children were divided in two groups; Group I: children with DS and group II: children without DS. In the two groups, the frequency of LIAVV whether isolated or associated with other CHD (excluding the atrioventricular canal), the distribution boy-girl and the various associated cardiac anomalies were studied. We used nonparametric tests for comparing the two groups. The p value < 0.05 was considered significant.
  
  
  RESULTS
  Group I consists of 155 patients including 31 (20%) with LIAVV, isolated in 22 cases (14.2%) and associated with CHD in 9 cases (5.8%). Group II was composed of 5995 patients; the incidence of LIAVV was 0.2% (14 patients) with apvalue < 0.00001. Regarding sex, there was a marked male predominance: respectively 78% and 56% in groups I and II. In patients with isolated LIAVV, 86% of patients were males. Family history of DS is found in 3/7 children without T21 with isolated LIAVV. A patient, in whom an atrial septal defect ostium primum type with LIAVV was diagnosed during the first month of life, has seen his septal defect closed spontaneously five months later.
  
  
  CONCLUSIONS
  Encountered predominantly among a male population, the isolated LIAVV is less frequent in children without DS but often with family history of Down's syndrom.
authors.forename: Ghassan
authors.initials: G
authors.lastname: Chehab
authors.forename: Zakhia
authors.initials: Z
authors.lastname: Saliba
authors.forename: Bernard
authors.initials: B
authors.lastname: Gerbaka
authors.forename: Tony
authors.initials: T
authors.lastname: Abdel-Massih
authors.forename: Issam
authors.initials: I
authors.lastname: El-Rassi
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D004314:Down Syndrome / Q000150:complications* / Q000601:surgery; D005260:Female; D006330:Heart Defects, Congenital / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007861:Lebanon; D008297:Male; D012737:Sex Factors; D016896:Treatment Outcome