title: Solid-phase-supported synthesis of morpholinoglycine oligonucleotide mimics.
abstract: An efficient solid-phase-supported peptide synthesis (SPPS) of morpholinoglycine oligonucleotide (MorGly) mimics has been developed. The proposed strategy includes a novel specially designed labile linker group containing the oxalyl residue and the 2-aminomethylmorpholino nucleoside analogues as first subunits.
authors.affiliation: Institute of Chemical Biology and Fundamental Medicine, SB RAS, Lavrent'ev Ave, 8, Novosibirsk 630090, Russia.
authors.forename: Tatyana V
authors.initials: TV
authors.lastname: Abramova
authors.affiliation: Institute of Chemical Biology and Fundamental Medicine, SB RAS, Lavrent'ev Ave, 8, Novosibirsk 630090, Russia ; Novosibirsk State University, Pirogova St. 2, Novosibirsk 630090, Russia.
authors.forename: Sergey S
authors.initials: SS
authors.lastname: Belov
authors.affiliation: Institute of Chemical Biology and Fundamental Medicine, SB RAS, Lavrent'ev Ave, 8, Novosibirsk 630090, Russia.
authors.forename: Yulia V
authors.initials: YV
authors.lastname: Tarasenko
authors.affiliation: Institute of Chemical Biology and Fundamental Medicine, SB RAS, Lavrent'ev Ave, 8, Novosibirsk 630090, Russia.
authors.forename: Vladimir N
authors.initials: VN
authors.lastname: Silnikov
keywords: labile linker; morpholino oligomers; oligonucleotide mimics; solid-phase-supported peptide synthesis (SPPS)