title: Recent advances in the management of cystic fibrosis.
abstract: Cystic fibrosis is a disease that still causes a reduced life expectancy. The treatment burden remains high for affected individuals with often a combination of multiple oral and inhaled medications, as well as physiotherapy, required on a daily basis. In this article, we look at an overview of the pathogenesis, how this might lead to treatment options and look at some of the available new therapies, all in the aim of increasing life expectancy and reducing treatment burden.
authors.affiliation: Imperial College, London, UK Royal Brompton and Harefield NHS Foundation Trust, London, UK.
authors.forename: Jane C
authors.initials: JC
authors.lastname: Davies
authors.affiliation: Royal Brompton and Harefield NHS Foundation Trust, London, UK.
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Ebdon
authors.affiliation: Frimley Park Hospital, Frimley, Surrey, UK.
authors.forename: Christopher
authors.initials: C
authors.lastname: Orchard
mesh_terms: D003550:Cystic Fibrosis / Q000209:etiology* / Q000378:metabolism / Q000628:therapy; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000378:metabolism; D006801:Humans
chemical_list: D019005:Cystic Fibrosis Transmembrane Conductance Regulator
keywords: Cystic Fibrosis; Therapeutics