title: Recommendations for the management of acute hepatitis B: position paper of the Italian Society for the Study of Infectious and Tropical Diseases (SIMIT).
abstract: OBJECTIVE
  To develop recommendations for the management of acute hepatitis B by the Italian Society for the Study of Infectious and Tropical Diseases.
  
  
  METHODS
  Development of the recommendations divided into three levels of evidence according to the GRADE system: A (high), B (medium) and C (low experts opinion), together with three recommendation levels: 1 (strong), 2 (medium), 3 (weak).
  
  
  RESULTS
  The treatment with antivirals is in selected cases the mainstay of management of severe acute hepatitis, and should be started as a matter of urgency in order to prevent death.
  
  
  CONCLUSIONS
  These recommendations are meant to provide the rationale and practical indications for the management of acute hepatitis B (AHB).
authors.affiliation: Department of Infectious Diseases, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Via Taramelli, 5, 27100, Pavia, Italy, raffaele.bruno@unipv.it.
authors.forename: R
authors.initials: R
authors.lastname: Bruno
authors.forename: G
authors.initials: G
authors.lastname: Carosi
authors.forename: N
authors.initials: N
authors.lastname: Coppola
authors.forename: G B
authors.initials: GB
authors.lastname: Gaeta
authors.forename: M
authors.initials: M
authors.lastname: Puoti
authors.forename: T
authors.initials: T
authors.lastname: Santantonio
authors.forename: G
authors.initials: G
authors.lastname: Taliani
authors.forename: O
authors.initials: O
authors.lastname: Armignacco
authors.forename: E
authors.initials: E
authors.lastname: Sagnelli
authors.forename: M
authors.initials: M
authors.lastname: Andreoni
authors.forename: G
authors.initials: G
authors.lastname: Angarano
authors.forename: G
authors.initials: G
authors.lastname: Di Perri
authors.forename: G
authors.initials: G
authors.lastname: D'Offizi
authors.forename: M
authors.initials: M
authors.lastname: Galli
authors.forename: G
authors.initials: G
authors.lastname: Rizzardini
mesh_terms: D000208:Acute Disease; D000998:Antiviral Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D006509:Hepatitis B / Q000188:drug therapy* / Q000628:therapy / Q000821:virology; D006801:Humans; D007558:Italy; D016031:Liver Transplantation
chemical_list: D000998:Antiviral Agents