title: Influence of inhomogeneous static magnetic field-exposure on patients with erosive gastritis: a randomized, self- and placebo-controlled, double-blind, single centre, pilot study.
abstract: This pilot study was devoted to the effect of static magnetic field (SMF)-exposure on erosive gastritis. The randomized, self- and placebo-controlled, double-blind, pilot study included 16 patients of the 2nd Department of Internal Medicine, Semmelweis University diagnosed with erosive gastritis. The instrumental analysis followed a qualitative (pre-intervention) assessment of the symptoms by the patient: lower heartburn (in the ventricle), upper heartburn (in the oesophagus), epigastric pain, regurgitation, bloating and dry cough. Medical diagnosis included a double-line upper panendoscopy followed by 30 min local inhomogeneous SMF-exposure intervention at the lower sternal region over the stomach with peak-to-peak magnetic induction of 3 mT and 30 mT m(-1) gradient at the target site. A qualitative (post-intervention) assessment of the same symptoms closed the examination. Sham- or SMF-exposure was used in a double-blind manner. The authors succeeded in justifying the clinically and statistically significant beneficial effect of the SMF- over sham-exposure on the symptoms of erosive gastritis, the average effect of inhibition was 56% by p = 0.001, n = 42 + 96. This pilot study was aimed to encourage gastroenterologists to test local, inhomogeneous SMF-exposure on erosive gastritis patients, so this intervention may become an evidence-based alternative or complementary method in the clinical use especially in cases when conventional therapy options are contraindicated.
authors.affiliation: 2nd Department of Internal Medicine, Semmelweis University, Budapest, Szentkirályi u. 46, 1088, Hungary.
authors.forename: Márk
authors.initials: M
authors.lastname: Juhász
authors.affiliation: 2nd Department of Internal Medicine, Semmelweis University, Budapest, Szentkirályi u. 46, 1088, Hungary.
authors.forename: Viktor L
authors.initials: VL
authors.lastname: Nagy
authors.affiliation: 2nd Department of Internal Medicine, Semmelweis University, Budapest, Szentkirályi u. 46, 1088, Hungary.
authors.forename: Hajnal
authors.initials: H
authors.lastname: Székely
authors.affiliation: 2nd Department of Internal Medicine, Semmelweis University, Budapest, Szentkirályi u. 46, 1088, Hungary.
authors.forename: Dorottya
authors.initials: D
authors.lastname: Kocsis
authors.affiliation: 2nd Department of Internal Medicine, Semmelweis University, Budapest, Szentkirályi u. 46, 1088, Hungary.
authors.forename: Zsolt
authors.initials: Z
authors.lastname: Tulassay
authors.affiliation: e-Comers LLC, Csejtei u. 1-3, Budapest 1025, Hungary Department of Computer Science, University of Debrecen, Kassai út 26, Debrecen 4028, Hungary laszlo.janos@inf.unideb.hu.
authors.forename: János F
authors.initials: JF
authors.lastname: László
mesh_terms: D000328:Adult; D000368:Aged; D004311:Double-Blind Method; D005260:Female; D005756:Gastritis / Q000175:diagnosis / Q000628:therapy*; D006356:Heartburn / Q000175:diagnosis; D006801:Humans; D055909:Magnetic Field Therapy / Q000379:methods*; D060526:Magnetic Fields; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000175:diagnosis; D010865:Pilot Projects; D016896:Treatment Outcome; D055815:Young Adult
keywords: double-blind; erosive gastritis; pilot study; randomized; self- and placebo-controlled; static magnetic field-exposure