title: Effects of laparoscopic ovarian endometriosis cystectomy combined with postoperative GnRH-a therapy on ovarian reserve, pregnancy, and outcome recurrence.
abstract: OBJECTIVE
  The aim of this study was to investigate the impacts of laparoscopic ovarian endometriosis cystectomy combined with postoperative GnRH-a therapy on ovarian reserve, pregnancy outcome and recurrence.
  
  
  METHODS
  This was a prospective control study. The experimental group: 63 patients with combinations of laparoscopic bilateral ovarian endometrial cystectomies and gonadotropin-releasing hormone agonist (GnRH-a) treatment for three months.
  
  
  METHODS
  62 patients with laparoscopic bilateral ovarian endometrial cystectomies. Benchmarks: the changes of follicle stimulating hormone (FSH) and FSH/luteinizing hormone (LH), etradiol (E2) in preoperative and postoperative three months or menstrual two to three days, menstrual two to three days after surgery, natural pregnancy, and cyst recurrence in 18th month during postoperative follow-up.
  
  
  RESULTS
  In experimental group after six months, the percentage of returned FSH accounted for 95.3% of normal range, in the control group it was 82.2%, and the difference was significant (p < 0.05). The natural pregnancy rate of preoperative infertility patients (57.1%) was higher than the control (36.8%) (p < 0.05). The recurrence rate of preoperative infertility patients (12.7%) was lower than the control (27.4%) (p < 0.05).
  
  
  CONCLUSIONS
  After bilateral laparoscopic ovarian endometrial cystectomy, an implement of GnRH-a therapy can improve the postoperative pregnancy rate, which changes with clinical stage and patient age, reduces ovarian recurrence, and its influence on ovarian reserve is lesser.
authors.forename: Xin-Hua
authors.initials: XH
authors.lastname: Yang
authors.forename: Fei
authors.initials: F
authors.lastname: Ji
authors.forename: AiXingZi
authors.initials: A
authors.lastname: AiLi
authors.forename: HaNiKeXi
authors.initials: H
authors.lastname: TuerXun
authors.forename: Yan
authors.initials: Y
authors.lastname: He
authors.forename: Yan
authors.initials: Y
authors.lastname: Ding
mesh_terms: D017024:Chemotherapy, Adjuvant; D004715:Endometriosis / Q000097:blood / Q000188:drug therapy / Q000601:surgery*; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists*; D006801:Humans; D007247:Infertility, Female / Q000097:blood / Q000209:etiology; D010535:Laparoscopy; D007986:Luteinizing Hormone / Q000097:blood; D010048:Ovarian Cysts / Q000097:blood / Q000188:drug therapy / Q000601:surgery*; D011184:Postoperative Period; D011247:Pregnancy; D018873:Pregnancy Rate; D012008:Recurrence; D013997:Time Factors
chemical_list: D007987:Gonadotropin-Releasing Hormone; D004958:Estradiol; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone