title: Quality of life after laparoscopic and open resection of colorectal cancer.
abstract: BACKGROUND
  The aim of the study was to evaluate quality of life (QOL) outcomes after colorectal surgery for cancer from a 6-month perspective at a single institution.
  
  
  METHODS
  Cohort study to prospectively assess postoperative QOL in patients who underwent elective colorectal resection at the University Hospital Ostrava. QOL was assessed using the validated Short Form 36 (SF-36v2™) questionnaire at fixed time points.
  
  
  RESULTS
  A total of 148 patients were enrolled in the study (83 and 65 patients underwent laparoscopic and open colorectal resection, respectively). Operative time was significantly longer (161 vs. 133 min; p = 0.0073) and length of hospital stay was significantly shorter (10.7 vs. 13.1 days; p = 0.0451) in the laparoscopic group. Overall 30-day morbidity rates were lower in the laparoscopic group, but the difference was not significant (27.7 vs. 33.8%; p = 0.2116). QOL scores were comparable in both study groups before surgery (p ≥ 0.05). QOL was statistically significantly lower 2 days and 1 week after open colorectal surgery compared with laparoscopic surgery. One month and 6 months after surgery, there were no statistically significant differences between groups.
  
  
  CONCLUSIONS
  The present study suggests a higher postoperative QOL during the first month after laparoscopic colorectal resection could be one of the benefits of laparoscopy.
authors.affiliation: Department of Surgery, University Hospital Ostrava, Ostrava, Czech Republic.
authors.forename: Peter
authors.initials: P
authors.lastname: Ihnát
authors.forename: Lubomír
authors.initials: L
authors.lastname: Martínek
authors.forename: Marcel
authors.initials: M
authors.lastname: Mitták
authors.forename: Petr
authors.initials: P
authors.lastname: Vávra
authors.forename: Lucia
authors.initials: L
authors.lastname: Ihnát Rudinská
authors.forename: Pavel
authors.initials: P
authors.lastname: Zonča
mesh_terms: D000368:Aged; D015331:Cohort Studies; D003082:Colectomy / Q000009:adverse effects / Q000379:methods*; D015179:Colorectal Neoplasms / Q000473:pathology / Q000601:surgery*; D018153:Czech Republic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects / Q000379:methods*; D007813:Laparotomy / Q000009:adverse effects / Q000379:methods*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D061646:Operative Time; D010147:Pain Measurement; D010149:Postoperative Pain / Q000503:physiopathology; D011446:Prospective Studies; D011788:Quality of Life; D018570:Risk Assessment; D016896:Treatment Outcome