title: Allenylphosphine oxides as simple scaffolds for phosphinoylindoles and phosphinoylisocoumarins.
abstract: A range of phosphinoylindoles was prepared in one-pot from functionalized propargyl alcohols and a suitable P(III) precursor via a base-mediated reaction. The reaction proceeds via the intermediacy of allenylphosphine oxides. Similarly, phosphinoylisocoumarins were prepared from allenylphosphine oxides in a trifluoroacetic acid-mediated reaction; the latter also acts as a solvent. Interestingly, in the presence of wet trifluoroacetic acid, in addition to phosphinoylisocoumarins, phosphorus-free isocoumarins were also obtained. Key products were characterized by single crystal X-ray crystallography.
authors.affiliation: School of Chemistry, University of Hyderabad, Hyderabad 500 046, A. P., India.
authors.forename: G
authors.initials: G
authors.lastname: Gangadhararao
authors.affiliation: School of Chemistry, University of Hyderabad, Hyderabad 500 046, A. P., India.
authors.forename: Ramesh
authors.initials: R
authors.lastname: Kotikalapudi
authors.affiliation: School of Chemistry, University of Hyderabad, Hyderabad 500 046, A. P., India.
authors.forename: M
authors.initials: M
authors.lastname: Nagarjuna Reddy
authors.affiliation: School of Chemistry, University of Hyderabad, Hyderabad 500 046, A. P., India.
authors.forename: K C Kumara
authors.initials: KC
authors.lastname: Swamy
keywords: allenes; indoles; isocoumarins; organophosphorus; phosphinoyl-heterocycles; propargyl alcohols