title: Is a highly linear relationship between the dose of quercetin and the pharmacological effect possible? - a comment on Liu, et al. Evaluation of antioxidant and immunity activities of quercetin in isoproterenol-treated rats. Molecules 2012, 17, 4281-4291.
abstract: We wish to offer some comments on the article by H. Liu et al. entitled "Evaluation of antioxidant and immunity activities of quercetin in isoproterenol-treated rats", published in Molecules in 2012 [1]. [...].
authors.affiliation: Department of Pharmacology and Toxicology, Charles University in Prague, Faculty of Pharmacy in Hradec Králové, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic. mladenkap@faf.cuni.cz.
authors.forename: Přemysl
authors.initials: P
authors.lastname: Mladěnka
authors.affiliation: Department of Pharmacology and Toxicology, Charles University in Prague, Faculty of Pharmacy in Hradec Králové, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.
authors.forename: Radomír
authors.initials: R
authors.lastname: Hrdina
authors.affiliation: Department of Pharmacology and Toxicology, Charles University in Prague, Faculty of Pharmacy in Hradec Králové, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.
authors.forename: Tomáš
authors.initials: T
authors.lastname: Filipský
authors.affiliation: Department of Pharmacology and Toxicology, Charles University in Prague, Faculty of Pharmacy in Hradec Králové, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.
authors.forename: Michal
authors.initials: M
authors.lastname: Ríha
authors.affiliation: Charles University in Prague, Faculty of Medicine in Hradec Králové, Šimkova 870, 500 38 Hradec Králové, Czech Republic.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Palicka
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D007155:Immunologic Factors / Q000494:pharmacology*; D017202:Myocardial Ischemia / Q000188:drug therapy*; D011794:Quercetin / Q000494:pharmacology*
chemical_list: D000975:Antioxidants; D007155:Immunologic Factors; D011794:Quercetin