title: Primary diffuse large B-cell non-Hodgkin lymphoma of the paranasal sinuses presenting as cavernous sinus syndrome.
abstract: Primary paranasal sinus lymphoma is an uncommon malignancy that accounts for only 0.17% of all lymphomas and is often difficult to diagnose. Initially, tumors in this area cause very few symptoms and are at an advanced stage at the time of diagnosis. Ophthalmologic signs and symptoms occur early in the disease process because of close proximity of the orbit to the paranasal sinuses. We report on a case of primary malignant lymphoma of the sphenoid and ethmoid sinuses with involvement of the cavernous sinus, initially presenting with ophthalmologic signs and symptoms in association with cavernous sinus syndrome.
authors.affiliation: From the *Department of Ophthalmology, Korea University College of Medicine, Ansan; †Department of Ophthalmology, KEPCO Medical Center, Seoul; and ‡Department of Otolaryngology, Korea University College of Medicine, Ansan, South Korea.
authors.forename: Hwa
authors.initials: H
authors.lastname: Lee
authors.forename: Kwang-Eon
authors.initials: KE
authors.lastname: Choi
authors.forename: Minsoo
authors.initials: M
authors.lastname: Park
authors.forename: Seung Hoon
authors.initials: SH
authors.lastname: Lee
authors.forename: Sehyun
authors.initials: S
authors.lastname: Baek
mesh_terms: D000368:Aged; D002426:Cavernous Sinus / Q000473:pathology*; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D018450:Disease Progression; D005005:Ethmoid Sinus / Q000473:pathology*; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology* / Q000628:therapy*; D008297:Male; D009361:Neoplasm Invasiveness; D009886:Ophthalmoplegia / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D010255:Paranasal Sinus Neoplasms / Q000473:pathology* / Q000628:therapy; D013101:Sphenoid Sinus / Q000473:pathology*; D013577:Syndrome