title: Multi-modal CT scanning in the evaluation of cerebrovascular disease patients.
abstract: Ischemic stroke currently represents one of the leading causes of severe disability and mortality in the Western World. Until now, angiography was the most used imaging technique for the detection of the extra-cranial and intracranial vessel pathology. Currently, however, non-invasive imaging tool like ultrasound (US), magnetic resonance (MR) and computed tomography (CT) have proven capable of offering a detailed analysis of the vascular system. CT in particular represents an advanced system to explore the pathology of carotid arteries and intracranial vessels and also offers tools like CT perfusion (CTP) that provides valuable information of the brain's vascular physiology by increasing the stroke diagnostic. In this review, our purpose is to discuss stroke risk prediction and detection using CT.
authors.affiliation: 1 Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.), di Cagliari - Polo di Monserrato s.s. 554 Monserrato (Cagliari) 09045, Italy ; 2 Departments of Radiological Sciences, University of Rome La Sapienza, Viale Regina Elena 324, 00161 (Rome), Italy ; 3 Department of Radiology, University of Washington, Seattle, Washington, USA ; 4 Fellow AIMBE, CTO, AtheroPoint LLC, Roseville, CA, USA ; 5 Department of Biomedical Engineering, Idaho State University (Aff.), ID, USA ; 6 Department of Radiology, New York University School of Medicine, New York, USA ; 7 Department of Neurology and Psychiatry, Sapienza University of Rome, Viale dell' Università, 30, 00185 Rome, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Saba
authors.affiliation: 1 Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.), di Cagliari - Polo di Monserrato s.s. 554 Monserrato (Cagliari) 09045, Italy ; 2 Departments of Radiological Sciences, University of Rome La Sapienza, Viale Regina Elena 324, 00161 (Rome), Italy ; 3 Department of Radiology, University of Washington, Seattle, Washington, USA ; 4 Fellow AIMBE, CTO, AtheroPoint LLC, Roseville, CA, USA ; 5 Department of Biomedical Engineering, Idaho State University (Aff.), ID, USA ; 6 Department of Radiology, New York University School of Medicine, New York, USA ; 7 Department of Neurology and Psychiatry, Sapienza University of Rome, Viale dell' Università, 30, 00185 Rome, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Anzidei
authors.affiliation: 1 Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.), di Cagliari - Polo di Monserrato s.s. 554 Monserrato (Cagliari) 09045, Italy ; 2 Departments of Radiological Sciences, University of Rome La Sapienza, Viale Regina Elena 324, 00161 (Rome), Italy ; 3 Department of Radiology, University of Washington, Seattle, Washington, USA ; 4 Fellow AIMBE, CTO, AtheroPoint LLC, Roseville, CA, USA ; 5 Department of Biomedical Engineering, Idaho State University (Aff.), ID, USA ; 6 Department of Radiology, New York University School of Medicine, New York, USA ; 7 Department of Neurology and Psychiatry, Sapienza University of Rome, Viale dell' Università, 30, 00185 Rome, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Piga
authors.affiliation: 1 Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.), di Cagliari - Polo di Monserrato s.s. 554 Monserrato (Cagliari) 09045, Italy ; 2 Departments of Radiological Sciences, University of Rome La Sapienza, Viale Regina Elena 324, 00161 (Rome), Italy ; 3 Department of Radiology, University of Washington, Seattle, Washington, USA ; 4 Fellow AIMBE, CTO, AtheroPoint LLC, Roseville, CA, USA ; 5 Department of Biomedical Engineering, Idaho State University (Aff.), ID, USA ; 6 Department of Radiology, New York University School of Medicine, New York, USA ; 7 Department of Neurology and Psychiatry, Sapienza University of Rome, Viale dell' Università, 30, 00185 Rome, Italy.
authors.forename: Federica
authors.initials: F
authors.lastname: Ciolina
authors.affiliation: 1 Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.), di Cagliari - Polo di Monserrato s.s. 554 Monserrato (Cagliari) 09045, Italy ; 2 Departments of Radiological Sciences, University of Rome La Sapienza, Viale Regina Elena 324, 00161 (Rome), Italy ; 3 Department of Radiology, University of Washington, Seattle, Washington, USA ; 4 Fellow AIMBE, CTO, AtheroPoint LLC, Roseville, CA, USA ; 5 Department of Biomedical Engineering, Idaho State University (Aff.), ID, USA ; 6 Department of Radiology, New York University School of Medicine, New York, USA ; 7 Department of Neurology and Psychiatry, Sapienza University of Rome, Viale dell' Università, 30, 00185 Rome, Italy.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Mannelli
authors.affiliation: 1 Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.), di Cagliari - Polo di Monserrato s.s. 554 Monserrato (Cagliari) 09045, Italy ; 2 Departments of Radiological Sciences, University of Rome La Sapienza, Viale Regina Elena 324, 00161 (Rome), Italy ; 3 Department of Radiology, University of Washington, Seattle, Washington, USA ; 4 Fellow AIMBE, CTO, AtheroPoint LLC, Roseville, CA, USA ; 5 Department of Biomedical Engineering, Idaho State University (Aff.), ID, USA ; 6 Department of Radiology, New York University School of Medicine, New York, USA ; 7 Department of Neurology and Psychiatry, Sapienza University of Rome, Viale dell' Università, 30, 00185 Rome, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Catalano
authors.affiliation: 1 Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.), di Cagliari - Polo di Monserrato s.s. 554 Monserrato (Cagliari) 09045, Italy ; 2 Departments of Radiological Sciences, University of Rome La Sapienza, Viale Regina Elena 324, 00161 (Rome), Italy ; 3 Department of Radiology, University of Washington, Seattle, Washington, USA ; 4 Fellow AIMBE, CTO, AtheroPoint LLC, Roseville, CA, USA ; 5 Department of Biomedical Engineering, Idaho State University (Aff.), ID, USA ; 6 Department of Radiology, New York University School of Medicine, New York, USA ; 7 Department of Neurology and Psychiatry, Sapienza University of Rome, Viale dell' Università, 30, 00185 Rome, Italy.
authors.forename: Jasjit S
authors.initials: JS
authors.lastname: Suri
authors.affiliation: 1 Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.), di Cagliari - Polo di Monserrato s.s. 554 Monserrato (Cagliari) 09045, Italy ; 2 Departments of Radiological Sciences, University of Rome La Sapienza, Viale Regina Elena 324, 00161 (Rome), Italy ; 3 Department of Radiology, University of Washington, Seattle, Washington, USA ; 4 Fellow AIMBE, CTO, AtheroPoint LLC, Roseville, CA, USA ; 5 Department of Biomedical Engineering, Idaho State University (Aff.), ID, USA ; 6 Department of Radiology, New York University School of Medicine, New York, USA ; 7 Department of Neurology and Psychiatry, Sapienza University of Rome, Viale dell' Università, 30, 00185 Rome, Italy.
authors.forename: Eytan
authors.initials: E
authors.lastname: Raz
keywords: CT perfusion (CTP); CT-angiography (CTA); Computed tomography (CT); carotid artery; stroke; vulnerable plaque