title: B-acute lymphoblastic leukaemia.
abstract: A 13-year-old boy presented with fever, skeletal pain, polydipsia, polyuria and multiple osteolytic lesions in pelvic bones and upper femur. There was no organomegaly or lymphadenopathy. His serum calcium levels were raised. Peripheral blood film examination was normal. Bone marrow showed presence of blast cells. Flowcytometry indicated B-acute lymphoblastic leukaemia (B-ALL). Hypercalcaemia and osteolytic lesions are rare presentations of B-ALL. This should be kept as a differential if a child presents with unexplained skeletal pain with lytic lesions.
authors.affiliation: Department of Pathology, KGMU, Lucknow, Uttar Pradesh, India.
authors.forename: Rashmi
authors.initials: R
authors.lastname: Kushwaha
authors.affiliation: Department of Pathology, KGMU, Lucknow, Uttar Pradesh, India.
authors.forename: Ashutosh
authors.initials: A
authors.lastname: Kumar
authors.affiliation: Department of Pathology, KGMU, Lucknow, Uttar Pradesh, India.
authors.forename: Mili
authors.initials: M
authors.lastname: Jain
authors.affiliation: Department of Pathology, KGMU, Lucknow, Uttar Pradesh, India.
authors.forename: Uma Shankar
authors.initials: US
authors.lastname: Singh
mesh_terms: D000293:Adolescent; D001853:Bone Marrow / Q000473:pathology*; D001856:Bone Marrow Examination; D001842:Bone and Bones / Q000473:pathology*; D006801:Humans; D006934:Hypercalcemia / Q000175:diagnosis* / Q000209:etiology; D008297:Male; D059352:Musculoskeletal Pain / Q000209:etiology; D010014:Osteolysis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D059606:Polydipsia / Q000209:etiology; D011141:Polyuria / Q000209:etiology; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D011859:Radiography