title: Peptide nucleic acid - an opportunity for bio-nanotechnology.
abstract: DNA is a major player in the field of bio-nanotechnology and many interesting applications have been realized using this oligonucleotide. In contrast, the use of peptide nucleic acid (PNA), which is a non-natural, neutral analogue of DNA with superior hybridization strengths compared to DNA, is still in its infancy in bio-nanotechnology. However, as demonstrated in this short review using selected studies, promising examples demonstrating the tremendous opportunities that PNA can offer for bio-nanotechnology were recently described.
authors.affiliation: University of Zurich Department of Chemistry Winterthurerstrasse 190 CH-8057 Zurich, Switzerland.
authors.forename: Philipp
authors.initials: P
authors.lastname: Anstaett
authors.affiliation: University of Zurich Department of Chemistry Winterthurerstrasse 190 CH-8057 Zurich, Switzerland. gilles.gasser@chem.uzh.ch.
authors.forename: Gilles
authors.initials: G
authors.lastname: Gasser
mesh_terms: D015374:Biosensing Techniques; D004247:DNA / Q000032:analysis* / Q000737:chemistry; D006046:Gold / Q000737:chemistry; D053768:Metal Nanoparticles / Q000737:chemistry; D036103:Nanotechnology; D009693:Nucleic Acid Hybridization; D020135:Peptide Nucleic Acids / Q000138:chemical synthesis / Q000737:chemistry*; D013059:Spectrum Analysis, Raman
chemical_list: D020135:Peptide Nucleic Acids; D006046:Gold; D004247:DNA