title: A case of primary subglottic malignant melanoma with a successful surgical treatment.
abstract: Primary subglottic malignant melanoma is a very rare and underdiagnosed neoplasm. We are reporting a case of primary malignant melanoma of subglottic mucosa in a 78-year-old woman who presented to our hospital with shortness of breath and hoarseness of voice. Laryngoscopy and excisional biopsy along with immunoreactivity to S-100 and human melanoma black-45 (HMB-45) confirmed the diagnosis. The patient was treated with laryngectomy followed by radiotherapy. Five years following surgical treatment, she continues to be asymptomatic. To our knowledge, there is only one reported case of primary malignant melanoma of subglottic mucosa in the medical literatures.
authors.affiliation: Department of Medicine, Conemaugh Memorial Medical Center, Johnstown, PA 15905, USA.
authors.forename: Shahzad
authors.identifier: 0000-0002-1761-0847
authors.initials: S
authors.lastname: Ahmad
authors.affiliation: Department of Medicine, Conemaugh Memorial Medical Center, Johnstown, PA 15905, USA.
authors.forename: Mahmoud
authors.identifier: 0000-0002-0643-2168
authors.initials: M
authors.lastname: Abdelghany
authors.affiliation: Department of Anatomic and Clinical Pathology, Conemaugh Memorial Medical Center, Johnstown, PA 15905, USA.
authors.forename: Curtis
authors.initials: C
authors.lastname: Goldblatt
authors.affiliation: Department of Radiology, Conemaugh Memorial Medical Center, Johnstown, PA 15905, USA.
authors.forename: Owen
authors.initials: O
authors.lastname: Stark
authors.affiliation: Department of Otolaryngology, Conemaugh Memorial Medical Center, Johnstown, PA 15905, USA.
authors.forename: Nicholas
authors.initials: N
authors.lastname: Masciotra