title: Classification of non-Hodgkin lymphoma in Algeria according to the World Health Organization classification.
abstract: The relative distribution of non-Hodgkin lymphoma (NHL) subtypes differs markedly around the world. The aim of this study was to report this distribution in Algeria. A panel of four hematopathologists classified 197 consecutive cases according to the World Health Organization classification, including 87.3% B-cell and 12.7% T- or natural killer (NK)-cell NHLs. This series was compared with similar cohorts from Western Europe (WEU) and North America (NA). Algeria had a significantly higher frequency of diffuse large B-cell lymphoma (DLBCL: 52.8%) and a lower frequency of follicular lymphoma (FL: 13.2%) compared with WEU (DLBCL: 32.2%; FL: 20.0%) and NA (DLBCL: 29.3%; FL: 33.6%). The frequency of mantle cell lymphoma was lower in Algeria (2.5%) compared with WEU (8.3%). Smaller differences were also found among the NK/T-cell lymphomas. In conclusion, we found important differences between Algeria and Western countries, and further epidemiologic studies are needed to explain these differences.
authors.affiliation: Department of Clinical Hematology, University Pierre and Marie Curie , Algiers , Algeria.
authors.forename: Nadia
authors.initials: N
authors.lastname: Boudjerra
authors.forename: Anamarija M
authors.initials: AM
authors.lastname: Perry
authors.forename: Josée
authors.initials: J
authors.lastname: Audouin
authors.forename: Jacques
authors.initials: J
authors.lastname: Diebold
authors.forename: Bharat N
authors.initials: BN
authors.lastname: Nathwani
authors.forename: Kenneth A
authors.initials: KA
authors.lastname: MacLennan
authors.forename: Hans K
authors.initials: HK
authors.lastname: Müller-Hermelink
authors.forename: Martin
authors.initials: M
authors.lastname: Bast
authors.forename: Eugene
authors.initials: E
authors.lastname: Boilesen
authors.forename: James O
authors.initials: JO
authors.lastname: Armitage
authors.forename: Dennis D
authors.initials: DD
authors.lastname: Weisenburger
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000462:Algeria / Q000453:epidemiology; D001402:B-Lymphocytes / Q000473:pathology; D002648:Child; D005060:Europe / Q000453:epidemiology; D005260:Female; D006801:Humans; D007694:Killer Cells, Natural / Q000473:pathology; D008224:Lymphoma, Follicular / Q000453:epidemiology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000453:epidemiology; D020522:Lymphoma, Mantle-Cell / Q000453:epidemiology; D008228:Lymphoma, Non-Hodgkin / Q000145:classification* / Q000453:epidemiology*; D016399:Lymphoma, T-Cell / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009656:North America / Q000453:epidemiology; D013601:T-Lymphocytes / Q000473:pathology; D014944:World Health Organization; D055815:Young Adult
keywords: Algeria; Non-Hodgkin lymphoma; diffuse large B-cell lymphoma; epidemiology