title: Prioritizing a research agenda: a Delphi study of the better outcomes through research for newborns (BORN) network.
abstract: BACKGROUND
  There is a paucity of evidence to guide clinical management for term and late preterm newborns. The Better Outcomes through Research for Newborns (BORN) network is a national collaborative of clinicians formed to increase the evidence-base for well newborn care.
  
  
  OBJECTIVE
  To develop a consensus-based, prioritized research agenda for well newborn care.
  
  
  METHODS
  A two-round modified Delphi survey of BORN members was conducted. Round 1 was an open-ended survey soliciting 5 clinical questions identified as important and under-researched. Using qualitative methods, 20 most common themes were extracted and transformed into research questions. Round 2 survey respondents ranked the top 20 questions using a 5- point Likert scale and a quantitative analysis was conducted.
  
  
  RESULTS
  Round 1 survey generated 439 unique research questions that fell into 57 themes. In the Round 2 survey, the highest rated questions were: 1) At what weight-loss percentage is it medically necessary to formula supplement a breastfeeding infant? 2) What is the optimal management of infants with neonatal abstinence syndrome? 3) How and when should we initiate a workup for sepsis, and how should these newborns be managed?
  
  
  CONCLUSIONS
  Research priorities of clinicians include criteria for medically indicated formula supplementation of the breastfed newborn, management of neonatal abstinence syndrome and management of newborns at-risk for sepsis.
authors.affiliation: University of Missouri-Kansas City School of Medicine, Children's Mercy Hospital Kansas City, Missouri easimpson@cmh.edu.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Simpson
authors.affiliation: Division of Neonatology and Division of Hospital Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
authors.forename: Neera K
authors.initials: NK
authors.lastname: Goyal
authors.affiliation: Academic Pediatric Association, McLean, Virginia.
authors.forename: Niramol
authors.initials: N
authors.lastname: Dhepyasuwan
authors.affiliation: University of California at San Francisco, San Francisco, California.
authors.forename: Valerie J
authors.initials: VJ
authors.lastname: Flaherman
authors.affiliation: Nemours and Jefferson Medical College, Philadelphia, Pennsylvania.
authors.forename: Esther K
authors.initials: EK
authors.lastname: Chung
authors.affiliation: Holy Cross Health, Silver Spring, Maryland.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Von Kohorn
authors.affiliation: Well Newborn Care, Kaiser Permanente, Downey, California.
authors.forename: Anthony
authors.initials: A
authors.lastname: Burgos
authors.affiliation: Department of Pediatrics, University of Washington, Seattle, and Newborn Nursery, University of Washington Medical Center, Seattle, Washington.
authors.forename: James
authors.initials: J
authors.lastname: Taylor
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003697:Delphi Technique; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009359:Neonatology; D017063:Outcome Assessment, Health Care; D012106:Research
keywords: Delphi technique; academic medical centers; infant; newborn; nursery