title: [Embryo implantation: role of interleukin 1 family members].
abstract: Endometrial receptivity to embryo implantation is one of the fundamental features of reproduction. Success of natural or assisted embryo implantation is low (20-25%). Implantation remains the result of a successful collaboration, tightly regulated and closely coordinated, between maternal and embryonic tissues located at the crossroads of endocrinology and immunology. In scientific terms, this collaboration is a mystery of human reproduction. The implanted blastocyst within the endometrium is dependent on a fine-tuned synchronization. Therefore, an accurate dialogue between the mother and the embryo is timely required to orchestrate mutual and well-synchronized changes in the developing embryo and maternal responsiveness in order to achieve a successful implantation. Maternal-derived mediators, such as steroid hormones, matrix-degrading enzymes, integrins, cytokines, chemokines, and many embryonic growth factors could be involved in the feto-maternal dialogue. Therefore, what is the maternal molecular signature compatible with embryo implantation?
authors.affiliation: Endocrinologie de la reproduction, centre de recherche hôpital Saint-François d'Assise, centre hospitalier universitaire de Québec, faculté de médecine, université Laval, Québec, Canada.
authors.forename: Amélie
authors.initials: A
authors.lastname: Bourdiec
authors.affiliation: Endocrinologie de la reproduction, centre de recherche hôpital Saint-François d'Assise, centre hospitalier universitaire de Québec, faculté de médecine, université Laval, Québec, Canada.
authors.forename: Ali
authors.initials: A
authors.lastname: Akoum
mesh_terms: D000818:Animals; D016207:Cytokines / Q000502:physiology; D010064:Embryo Implantation / Q000235:genetics*; D004622:Embryo, Mammalian / Q000276:immunology / Q000378:metabolism; D004717:Endometrium / Q000276:immunology / Q000378:metabolism; D005260:Female; D006801:Humans; D007109:Immunity; D007375:Interleukin-1 / Q000502:physiology*; D011247:Pregnancy; D018523:Tropism / Q000276:immunology
chemical_list: D016207:Cytokines; D007375:Interleukin-1