title: Human papillomavirus testing in head and neck squamous cell carcinoma: best practice for diagnosis.
abstract: Human papillomavirus (HPV)-associated oropharyngeal carcinoma is now recognized as a clinically distinct subtype of head and neck cancer with important prognostic implications. HPV testing is recommended as the standard of care for all patients diagnosed with oropharyngeal squamous cell carcinoma. Here, we describe a practical approach to HPV testing within the setting of the diagnostic histopathology laboratory.
authors.affiliation: Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Pembroke Place, Liverpool, Merseyside, L3 5PS, UK.
authors.forename: Andrew
authors.initials: A
authors.lastname: Schache
authors.forename: James
authors.initials: J
authors.lastname: Croud
authors.forename: Max
authors.initials: M
authors.lastname: Robinson
authors.forename: Selvam
authors.initials: S
authors.lastname: Thavaraj
mesh_terms: D000465:Algorithms; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000473:pathology / Q000821:virology*; D004279:DNA, Viral / Q000235:genetics; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000821:virology*; D006801:Humans; D007150:Immunohistochemistry; D017403:In Situ Hybridization; D027383:Papillomaviridae / Q000235:genetics / Q000302:isolation & purification* / Q000502:physiology*; D016133:Polymerase Chain Reaction; D012306:Risk; D000077195:Squamous Cell Carcinoma of Head and Neck
chemical_list: D004279:DNA, Viral