title: Evaluation of the measles, mumps and rubella vaccination catch-up campaign in England in 2013.
abstract: In January-March 2013 in England, confirmed measles cases increased in children aged 10-16 years. In April-September 2013, the National Health System and Public Health England launched a national measles-mumps-rubella (MMR) campaign based on data from Child Health Information Systems (CHIS) estimating that approximately 8% in this age group were unvaccinated. We estimated coverage at baseline, and, of those unvaccinated (target), the proportion vaccinated up to 20/08/2013 (mid-point) to inform further public health action. We selected a sample of 6644 children aged 10-16 years using multistage sampling from those reported unvaccinated in CHIS at baseline and validated their records against GP records. We adjusted the CHIS MMR vaccine coverage estimates correcting by the proportion of vaccinated children obtained through sample validation. We validated 5179/6644 (78%) of the sample records. Coverage at baseline was estimated as 94.7% (95% confidence intervals, CI: 93.5-96.0%), lower in London (86.9%, 95%CI: 83.0-90.9%) than outside (96.1%, 95%CI 95.5-96.8%). The campaign reached 10.8% (95%CI: 7.0-14.6%) of the target population, lower in London (7.1%, 95%CI: 4.9-9.3) than in the rest of England (11.4%, 95%CI: 7.0-15.9%). Coverage increased by 0.5% up to 95.3% (95% CI: 94.1-96.4%) but an estimated 210,000 10-16 year old children remained unvaccinated nationally. Baseline MMR coverage was higher than previously reported and was estimated to have reached the 95% campaign objective at midpoint. Eleven per cent of the target population were vaccinated during the campaign, and may be underestimated, especially in London. No further national campaigns are needed but targeted local vaccination activities should be considered.
authors.affiliation: Field Epidemiology Service (Victoria Office), Public Health England, 151 Buckingham Palace Road, London SW1W 9SZ, United Kingdom; European Programme for Intervention Epidemiology Training (EPIET), ECDC, Sweden. Electronic address: benedetto.simone@phe.gov.uk.
authors.forename: Benedetto
authors.initials: B
authors.lastname: Simone
authors.affiliation: Field Epidemiology Service (Victoria Office), Public Health England, 151 Buckingham Palace Road, London SW1W 9SZ, United Kingdom.
authors.forename: Sooria
authors.initials: S
authors.lastname: Balasegaram
authors.affiliation: Field Epidemiology Service (Bristol Office), Public Health England, 2 Rivergate Temple Quay, Bristol BS1 6EH, United Kingdom.
authors.forename: Maya
authors.initials: M
authors.lastname: Gobin
authors.affiliation: Field Epidemiology Service (Victoria Office), Public Health England, 151 Buckingham Palace Road, London SW1W 9SZ, United Kingdom.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Anderson
authors.affiliation: Statistics, Modelling and Economics Dept, Centre for Infectious Disease Surveillance and Control, Public Health England, Health Protection Directorate, 61 Colindale Avenue, London NW9 5EQ, United Kingdom.
authors.forename: André
authors.initials: A
authors.lastname: Charlett
authors.affiliation: Field Epidemiology Services (Leeds office), Public Health England, Quarry House, Quarry Hill, Leeds LS2 7UE, United Kingdom.
authors.forename: Louise
authors.initials: L
authors.lastname: Coole
authors.affiliation: Field Epidemiology Service (Victoria Office), Public Health England, 151 Buckingham Palace Road, London SW1W 9SZ, United Kingdom.
authors.forename: Helen
authors.initials: H
authors.lastname: Maguire
authors.affiliation: Statistics, Modelling and Economics Dept, Centre for Infectious Disease Surveillance and Control, Public Health England, Health Protection Directorate, 61 Colindale Avenue, London NW9 5EQ, United Kingdom.
authors.forename: Tom
authors.initials: T
authors.lastname: Nichols
authors.affiliation: Field Epidemiology Service (Victoria Office), Public Health England, 151 Buckingham Palace Road, London SW1W 9SZ, United Kingdom.
authors.forename: Chas
authors.initials: C
authors.lastname: Rawlings
authors.affiliation: Health Protection Services, Immunisation, Hepatitis, and Blood Safety Department, Public Health England, 61 Colindale Avenue, London NW9 5EQ, United Kingdom.
authors.forename: Mary
authors.initials: M
authors.lastname: Ramsay
authors.affiliation: Field Epidemiology Service (Bristol Office), Public Health England, 2 Rivergate Temple Quay, Bristol BS1 6EH, United Kingdom; University of Bristol, School of Social and Community Medicine, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, United Kingdom.
authors.forename: Isabel
authors.initials: I
authors.lastname: Oliver
mesh_terms: D000293:Adolescent; D002648:Child; D004739:England; D006306:Health Surveys; D006801:Humans; D017589:Immunization Programs / Q000706:statistics & numerical data*; D008457:Measles / Q000517:prevention & control*; D022542:Measles-Mumps-Rubella Vaccine / Q000627:therapeutic use*; D009107:Mumps / Q000517:prevention & control*; D011634:Public Health; D012409:Rubella / Q000517:prevention & control*
chemical_list: D022542:Measles-Mumps-Rubella Vaccine
keywords: England; Evaluation; Health campaigns; Measles-Mumps-Rubella Vaccine; Vaccination