title: A MYOD1 mutation cooperates with PI3K pathway activation in ERMS.
abstract: A recurring point mutation in MYOD1 is found in 10% of embryonal rhabdomyosarcomas (ERMS).
mesh_terms: D002454:Cell Differentiation; D006801:Humans; D020935:MAP Kinase Signaling System; D017570:MyoD Protein / Q000235:genetics*; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism*; D017354:Point Mutation; D011379:Prognosis; D018233:Rhabdomyosarcoma, Embryonal / Q000235:genetics* / Q000473:pathology
chemical_list: D017570:MyoD Protein; C057363:MyoD1 myogenic differentiation protein; D019869:Phosphatidylinositol 3-Kinases