title: Clinical characteristics of angioedema with eosinophilia.
abstract: Angioedema with eosinophilia (AE) is a very rare allergy disease, case reports of which have been published sporadically since 1984. Here, we retrospectively analyzed the clinical features of 10 AE patients in Korea. Nine of the 10 subjects were young females, ranging from 23 to 38 years old. Twenty percent of the subjects had episodic-type AE with high serum IgM and eosinophil counts, while 80% were non-episodic type with normal serum IgM levels but high eosinophil counts. All patients had used systemic corticosteroids to control AE. One patient with refractory episodic-type AE was treated with anti-IgE antibody. This is the first study to evaluate the clinical characteristics of AE in a Korean population.
authors.affiliation: Department of Allergy & Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
authors.forename: Hyo-Jung
authors.initials: HJ
authors.lastname: Cho
authors.affiliation: Department of Allergy & Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
authors.forename: Hye-Soo
authors.initials: HS
authors.lastname: Yoo
authors.affiliation: Department of Allergy & Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
authors.forename: Mi-Ae
authors.initials: MA
authors.lastname: Kim
authors.affiliation: Department of Allergy & Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
authors.forename: Yoo-Seob
authors.initials: YS
authors.lastname: Shin
authors.affiliation: Department of Allergy & Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
authors.forename: Young-Min
authors.initials: YM
authors.lastname: Ye
authors.affiliation: Department of Allergy & Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
authors.forename: Dong-Ho
authors.initials: DH
authors.lastname: Nahm
authors.affiliation: Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
authors.forename: Joo-Hee
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Dongtan, Korea.
authors.forename: Jeong-Hee
authors.initials: JH
authors.lastname: Choi
authors.affiliation: Department of Allergy & Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
authors.forename: Sun-Young
authors.initials: SY
authors.lastname: Park
authors.affiliation: Department of Allergy & Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
authors.forename: Hae-Sim
authors.identifier: 0000-0003-2614-0303
authors.initials: HS
authors.lastname: Park
keywords: Angioedema; anti-IgE antibody; eosinophilia