title: Nanofiltration, bipolar electrodialysis and reactive extraction hybrid system for separation of fumaric acid from fermentation broth.
abstract: A novel approach based on a hybrid system allowing nanofiltration, bipolar electrodialysis and reactive extraction, was proposed to remove fumaric acid from fermentation broth left after bioconversion of glycerol. The fumaric salts can be concentrated in the nanofiltration process to a high yield (80-95% depending on pressure), fumaric acid can be selectively separated from other fermentation components, as well as sodium fumarate can be conversed into the acid form in bipolar electrodialysis process (stack consists of bipolar and anion-exchange membranes). Reactive extraction with quaternary ammonium chloride (Aliquat 336) or alkylphosphine oxides (Cyanex 923) solutions (yield between 60% and 98%) was applied as the final step for fumaric acid recovery from aqueous streams after the membrane techniques. The hybrid system permitting nanofiltration, bipolar electrodialysis and reactive extraction was found effective for recovery of fumaric acid from the fermentation broth.
authors.affiliation: Poznan University of Technology, Institute of Chemical Technology and Engineering, pl. M. Skłodowskiej-Curie 2, 60-965 Poznań, Poland. Electronic address: krystyna.prochaska@put.poznan.pl.
authors.forename: Krystyna
authors.initials: K
authors.lastname: Prochaska
authors.affiliation: Poznan University of Technology, Institute of Chemical Technology and Engineering, pl. M. Skłodowskiej-Curie 2, 60-965 Poznań, Poland.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Staszak
authors.affiliation: Poznan University of Technology, Institute of Chemical Technology and Engineering, pl. M. Skłodowskiej-Curie 2, 60-965 Poznań, Poland.
authors.forename: Marta Joanna
authors.initials: MJ
authors.lastname: Woźniak-Budych
authors.affiliation: Poznan University of Technology, Institute of Chemical Technology and Engineering, pl. M. Skłodowskiej-Curie 2, 60-965 Poznań, Poland.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Regel-Rosocka
authors.affiliation: Poznan University of Technology, Institute of Chemical Technology and Engineering, pl. M. Skłodowskiej-Curie 2, 60-965 Poznań, Poland.
authors.forename: Michalina
authors.initials: M
authors.lastname: Adamczak
authors.affiliation: Poznan University of Technology, Institute of Chemical Technology and Engineering, pl. M. Skłodowskiej-Curie 2, 60-965 Poznań, Poland.
authors.forename: Maciej
authors.initials: M
authors.lastname: Wiśniewski
authors.affiliation: Poznan University of Technology, Institute of Chemical Technology and Engineering, pl. M. Skłodowskiej-Curie 2, 60-965 Poznań, Poland.
authors.forename: Jacek
authors.initials: J
authors.lastname: Staniewski
mesh_terms: D002851:Chromatography, High Pressure Liquid; D003956:Dialysis / Q000379:methods*; D004560:Electricity; D005285:Fermentation; D005374:Filtration / Q000379:methods*; D005650:Fumarates / Q000302:isolation & purification*; D006863:Hydrogen-Ion Concentration; D036103:Nanotechnology / Q000379:methods*; D010539:Permeability; D011312:Pressure; D012996:Solutions
chemical_list: D005650:Fumarates; D012996:Solutions; C032005:fumaric acid
keywords: Bipolar electrodialysis; Fermentation broth; Fumaric acid; Nanofiltration; Reactive extraction