title: Eosinophil interactions: antigen presentation.
abstract: Eosinophils have been demonstrated in a variety of experimental models to express MHC Class II and co-stimulatory molecules necessary to act as antigen presenting cells (APCs). They also have been experimentally observed to use these expressed proteins to function as APCs. This chapter reviews basic techniques to allow for in vitro and ex vivo experimentation of human and murine eosinophil APC function.
authors.affiliation: Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, KSB 23, 330 Brookline Avenue, 02215, Boston, MA, USA, pakuthot@bidmc.harvard.edu.
authors.forename: Praveen
authors.initials: P
authors.lastname: Akuthota
mesh_terms: D000818:Animals; D017951:Antigen Presentation / Q000502:physiology*; D000938:Antigen-Presenting Cells / Q000166:cytology; D004804:Eosinophils / Q000166:cytology*; D000949:Histocompatibility Antigens Class II / Q000378:metabolism; D006801:Humans; D051379:Mice
chemical_list: D000949:Histocompatibility Antigens Class II