title: Myxoid leiomyosarcoma of the Bartholin gland.
abstract: BACKGROUND
  Myxoid leiomyosarcomas originating from the Bartholin gland are exceedingly rare. Only one other case of a Bartholin gland myxoid leiomyosarcoma has been reported.
  
  
  METHODS
  Our patient presented with a 10 cm mass on her vulva, which was presumed to be a Bartholin gland cyst. Pathology showed a high-grade myxoid leiomyosarcoma with positive margins. She was treated with left radical hemivulvectomy, laparoscopic hysterectomy with bilateral salpingo-oophorectomy, and six cycles of adjuvant chemotherapy. She is now 1 year from completion of therapy and remains disease-free.
  
  
  CONCLUSIONS
  All solid vulvar masses should be thoroughly evaluated with a low threshold for biopsy. Treatment should consist of complete resection. Hormonal manipulation, chemotherapy, and radiation should be considered as potential adjuvant treatment options.
authors.affiliation: Departments of Obstetrics and Gynecology and Pathology, University of Michigan Medical Center, Ann Arbor, Michigan; and the Department of Obstetrics and Gynecology, Naval Medical Center San Diego, San Diego, California.
authors.forename: Erika L
authors.initials: EL
authors.lastname: Mowers
authors.forename: Jessica J
authors.initials: JJ
authors.lastname: Shank
authors.forename: Nora
authors.initials: N
authors.lastname: Frisch
authors.forename: R Kevin
authors.initials: RK
authors.lastname: Reynolds
mesh_terms: D001472:Bartholin's Glands / Q000473:pathology*; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D014846:Vulvar Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery