title: Ultrasonographic findings in hereditary neuropathy with liability to pressure palsies.
abstract: OBJECTIVE
  The aims of this study were to evaluate the sonographic findings of patients with hereditary neuropathy with liability to pressure palsies (HNPP) and to examine the correlation between sonographic and electrophysiological findings.
  
  
  METHODS
  Nine patients whose electrophysiological findings indicated HNPP and whose diagnosis was confirmed by genetic analysis were enrolled in the study. The median, ulnar, peroneal, and tibial nerves were evaluated by ultrasonography.
  
  
  RESULTS
  We ultrasonographically evaluated 18 median, ulnar, peroneal, and tibial nerves. Nerve enlargement was identified in the median, ulnar, and peroneal nerves at the typical sites of compression. None of the patients had nerve enlargement at a site of noncompression. None of the tibial nerves had increased cross-sectional area (CSA) values. There were no significant differences in median, ulnar, and peroneal nerve distal motor latencies (DMLs) between the patients with an increased CSA and those with a normal CSA. In most cases, there was no correlation between electrophysiological abnormalities and clinical or sonographic findings.
  
  
  CONCLUSIONS
  Although multiple nerve enlargements at typical entrapment sites on sonographic evaluation can suggest HNPP, ultrasonography cannot be used as a diagnostic tool for HNPP. Ultrasonography may contribute to the differential diagnosis of HNPP and other demyelinating polyneuropathies or compression neuropathies; however, further studies are required.
authors.forename: Ayse O
authors.initials: AO
authors.lastname: Bayrak
authors.forename: Ilkay Koray
authors.initials: IK
authors.lastname: Bayrak
authors.forename: Esra
authors.initials: E
authors.lastname: Battaloglu
authors.forename: Burcak
authors.initials: B
authors.lastname: Ozes
authors.forename: Onur
authors.initials: O
authors.lastname: Yildiz
authors.forename: Musa Kazim
authors.initials: MK
authors.lastname: Onar
mesh_terms: D000293:Adolescent; D000328:Adult; D001176:Arthrogryposis / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D015417:Hereditary Sensory and Motor Neuropathy / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008475:Median Nerve / Q000000981:diagnostic imaging* / Q000473:pathology / Q000502:physiology; D008875:Middle Aged; D009431:Neural Conduction / Q000502:physiology*; D010543:Peroneal Nerve / Q000000981:diagnostic imaging* / Q000473:pathology / Q000502:physiology; D013979:Tibial Nerve / Q000000981:diagnostic imaging* / Q000473:pathology / Q000502:physiology; D014459:Ulnar Nerve / Q000000981:diagnostic imaging* / Q000473:pathology / Q000502:physiology; D014463:Ultrasonography; D055815:Young Adult
keywords: Hereditary neuropathy,; Ultrasonography