title: [Relationship between resting heart rate and carotid artery structure in young hypertensive patients].
abstract: OBJECTIVE
  To investigate the relationship between resting heart rate (RHR) and carotid artery structure in young hypertensive patients.
  
  
  METHODS
  A total of 663 primary hypertensive patients aged between 18 and 45 (38.01 ± 5.78) were chosen from the First Affiliated Hospital of Xinjiang Medical University from January, 2009 to January, 2012. Patients under this study were divided into three groups according to their RHRs: group A (RHR<70 bpm, n = 163), group B (70 bpm≤RHR<80 bpm, n = 268), group C (RHR≥80 bpm, n = 232). Data on bilateral carotid artery intima-media thickness, common carotid artery diameter were detected by carotid ultra- sonography. Indexes of carotid artery were analyzed by both variance and bi-variate correlation analysis.
  
  
  RESULTS
  1) Differences in the blood pressure among three groups showed statistical significance (P < 0.01), with diastolic pressure in group A higher than in group B (P < 0.05), while both systolic and diastolic pressure in group C higher than in group B (P < 0.01). 2) In group A, the right carotid artery diameter was higher than in group C (P < 0.05) and the left carotid artery diameter higher than in group B (P < 0.05) with the left carotid artery diameter higher than in group C (P < 0.05). 3) Significant positive correlations were found between RHR and blood pressure (r = 0.112,0.118) and negative correlation between RHR and left carotid artery diameter (r = -0.89). However, correlation between RHR and right carotid artery diameter was not significant (r = -0.075, P = 0.068).
  
  
  CONCLUSIONS
  When blood pressure had an increase, we found that the carotid artery diameter was decreasing along with the increasing RHR among the young hypertensive patients.
authors.affiliation: Department of Outpatient, 69010 Unit PLA, Urumqi 830011, China.
authors.forename: Jianghong
authors.initials: J
authors.lastname: Song
authors.affiliation: Department of Hypertension, the First Affiliated of Xinjiang Medical University. Email: zymdxx@163.com.
authors.forename: Yuanming
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Outpatient, 69010 Unit PLA, Urumqi 830011, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Zhang
authors.affiliation: Department of Outpatient, 69010 Unit PLA, Urumqi 830011, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Jing
authors.affiliation: Department of Outpatient, 69010 Unit PLA, Urumqi 830011, China.
authors.forename: Lixia
authors.initials: L
authors.lastname: Wang
authors.affiliation: Department of Hypertension, the First Affiliated of Xinjiang Medical University.
authors.forename: Shasha
authors.initials: S
authors.lastname: Huang
authors.affiliation: Department of Hypertension, the People's Hospital of Xinjiang Uygur Autonomous Region.
authors.forename: Xinguo
authors.initials: X
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D002339:Carotid Arteries / Q000473:pathology*; D059168:Carotid Intima-Media Thickness; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000473:pathology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D055815:Young Adult