title: Sensitive voltammetric sensor based on isopropanol-Nafion-PSS-GR nanocomposite modified glassy carbon electrode for determination of clenbuterol in pork.
abstract: In the present study, poly(sodium 4-styrenesulfonate) (PSS) functionalized graphene (GR) was synthesised via a simple one-step chemical reduction of exfoliated graphite oxides in the presence of PSS. Characterisation of as-made nanocomposite using Fourier transform infrared spectroscopy (FT-IR) and ultraviolet and visible spectroscopy (UV-vis) clearly demonstrate the successful attachment of PSS to graphene sheets. A novel clenbuterol (CLB) electrochemical sensor was fabricated based on isopropanol-Nafion-PSS-GR composite film modified glassy carbon electrode. In the Britton-Robinson buffer (pH 1.2), the sensor exhibited superior electrocatalytic activity towards the oxidation of CLB. Applying linear sweep voltammetry, a good linear relationship of the oxidation peak current with respect to concentrations of CLB cross the range of 7.5 × 10(-8)-2.5 × 10(-5)mol L(-1) and a detection limit of 2.2 × 10(-8) mol L(-1) were achieved. The proposed method was successfully applied for the determination of CLB in pork.
authors.affiliation: The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China; Department of Chemistry, Zhengzhou Normal University, Zhengzhou 450001, PR China.
authors.forename: Ling
authors.initials: L
authors.lastname: Wang
authors.affiliation: The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China. Electronic address: yangran@zzu.edu.cn.
authors.forename: Ran
authors.initials: R
authors.lastname: Yang
authors.affiliation: The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.
authors.forename: Jing
authors.initials: J
authors.lastname: Chen
authors.affiliation: The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.
authors.forename: Jianjun
authors.initials: J
authors.lastname: Li
authors.affiliation: The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China; School of Chemistry & Chemical Engineering, Henan University of Technology, Zhengzhou 450001, PR China. Electronic address: qulingbo@zzu.edu.cn.
authors.forename: Lingbo
authors.initials: L
authors.lastname: Qu
authors.affiliation: Center for Intelligent Chemical Instrumentation, Department of Chemistry and Biochemistry, OHIO University, Athens, OH 45701-2979, USA.
authors.forename: Peter
authors.initials: P
authors.lastname: de B Harrington
mesh_terms: D019840:2-Propanol; D000318:Adrenergic beta-Agonists / Q000032:analysis*; D000818:Animals; D002244:Carbon / Q000737:chemistry; D002976:Clenbuterol / Q000032:analysis*; D004566:Electrodes; D005465:Fluorocarbon Polymers; D005506:Food Contamination / Q000032:analysis*; D006108:Graphite / Q000737:chemistry; D057230:Limit of Detection; D008460:Meat / Q000032:analysis*; D053761:Nanocomposites; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry; D010710:Phosphates; D011108:Polymers; D017550:Spectroscopy, Fourier Transform Infrared; D013451:Sulfonic Acids; D013552:Swine
chemical_list: D000318:Adrenergic beta-Agonists; D005465:Fluorocarbon Polymers; D010087:Oxides; D010710:Phosphates; D011108:Polymers; D013451:Sulfonic Acids; C040402:perfluorosulfonic acid; D002244:Carbon; D006108:Graphite; D019840:2-Propanol; C009285:sodium polymetaphosphate; D002976:Clenbuterol; C077114:styrenesulfonic acid polymer
keywords: Clenbuterol; Electrochemical sensor; Functionalized graphene; Poly(sodium 4-styrenesulfonate)