title: [Metabolic syndrome and cognitive dysfunction in the old age].
abstract: BACKGROUND
  We analyzed metabolic profile of patients with cognitive dysfunctions by means of levels of lipoproteins, glycaemia and hypertension.
  
  
  METHODS
  In naturalistic, open manner, we studied 100 persons--44 without cognitive dysfunctions, 17 with MCI and 39 with dementia. Patients were grouped according to ICD-10, NIA/AA, McKhann's criteria of cognitive impairment and STMS cutoff levels.
  
  
  RESULTS
  We found correlations between HDL cholesterol (p = 0.036, OR = 1.061, <0.99; 1.13>), hyperglycaemia (p = 0.008, OR = 0.97, <0.95; 0.99>), metabolic syndrome (p = 0.03; OR = 0.34; <0.12; 0.91>) with age (p = 0.001; OR = 0.9; <0.84; 0.95>) and dementia. We confirmed also correlations of glucose levels with CT changes (p = 0.01, OR = 0.97, <0.95; 0.99>), and age (r = -0.47, p = 0.000001), fasting glucose (r =-0.33, p = 0.0024), HDL levels (r = 0.32; p = 0.05) with STMS results.
  
  
  CONCLUSIONS
  Metabolic-cognitive syndrome seems to be a part of pathogenesis of dementia.
authors.forename: Tadeusz
authors.initials: T
authors.lastname: Parnowski
authors.forename: Bernadetta
authors.initials: B
authors.lastname: Kałuza
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000032:analysis; D015992:Body Mass Index; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003071:Cognition; D003072:Cognition Disorders / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D003704:Dementia / Q000175:diagnosis; D005260:Female; D006304:Health Status; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D008603:Mental Health; D024821:Metabolic Syndrome / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D014280:Triglycerides