title: Invited commentary.
authors.affiliation: Department of Cardiovascular Surgery, Ruijin Hospital, Shanghai Jiaotong University, Shanghai, China. Electronic address: dr.xiaofengye@gmail.com.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Ye
mesh_terms: D017545:Aortic Aneurysm, Thoracic / Q000503:physiopathology*; D001021:Aortic Valve / Q000002:abnormalities* / Q000503:physiopathology; D000082882:Bicuspid Aortic Valve Disease; D003094:Collagen / Q000502:physiology*; D005260:Female; D006349:Heart Valve Diseases / Q000503:physiopathology*; D006801:Humans; D008297:Male; D013718:Tensile Strength / Q000502:physiology*; D014261:Tricuspid Valve / Q000503:physiopathology*
chemical_list: D003094:Collagen