title: Menstruation disorders in adolescents with eating disorders-target body mass index percentiles for their resolution.
abstract: OBJECTIVE
  To analyse the progression of body mass index in eating disorders and to determine the percentile for establishment and resolution of the disease.
  
  
  METHODS
  A retrospective descriptive cross-sectional study. Review of clinical files of adolescents with eating disorders.
  
  
  RESULTS
  Of the 62 female adolescents studied with eating disorders, 51 presented with eating disorder not otherwise specified, 10 anorexia nervosa, and 1 bulimia nervosa. Twenty-one of these adolescents had menstrual disorders; in that, 14 secondary amenorrhea and 7 menstrual irregularities (6 eating disorder not otherwise specified, and 1 bulimia nervosa). In average, in anorectic adolescents, the initial body mass index was in 75th percentile; secondary amenorrhea was established 1 month after onset of the disease; minimum weight was 76.6% of ideal body mass index (at 4th percentile) at 10.2 months of disease; and resolution of amenorrhea occurred at 24 months, with average weight recovery of 93.4% of the ideal. In eating disorder not otherwise specified with menstrual disorder (n=10), the mean initial body mass index was at 85th percentile; minimal weight was in average 97.7% of the ideal value (minimum body mass index was in 52nd percentile) at 14.9 months of disease; body mass index stabilization occurred at 1.6 year of disease; and mean body mass index was in 73rd percentile. Considering eating disorder not otherwise specified with secondary amenorrhea (n=4); secondary amenorrhea occurred at 4 months, with resolution at 12 months of disease (mean 65th percentile body mass index).
  
  
  CONCLUSIONS
  One-third of the eating disorder group had menstrual disorder - two-thirds presented with amenorrhea. This study indicated that for the resolution of their menstrual disturbance the body mass index percentiles to be achieved by female adolescents with eating disorders was 25-50 in anorexia nervosa, and 50-75, in eating disorder not otherwise specified.
authors.affiliation: Hospital Pediátrico Carmona de Mota, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal.
authors.forename: Beatriz
authors.initials: B
authors.lastname: Vale
authors.affiliation: Centro Hospitalar de Leiria, Leiria, Portugal.
authors.forename: Sara
authors.initials: S
authors.lastname: Brito
authors.affiliation: Centro Hospitalar de Leiria, Leiria, Portugal.
authors.forename: Lígia
authors.initials: L
authors.lastname: Paulos
authors.affiliation: Centro Hospitalar de Leiria, Leiria, Portugal.
authors.forename: Pascoal
authors.initials: P
authors.lastname: Moleiro
mesh_terms: D000293:Adolescent; D000568:Amenorrhea / Q000209:etiology; D000856:Anorexia Nervosa / Q000150:complications; D015992:Body Mass Index; D001835:Body Weight; D002032:Bulimia / Q000150:complications; D002648:Child; D003430:Cross-Sectional Studies; D001068:Feeding and Eating Disorders / Q000150:complications*; D005260:Female; D006801:Humans; D008599:Menstruation Disturbances / Q000209:etiology*; D012189:Retrospective Studies