title: Morphological and immunohistological characteristics of follicular-compact thyroid carcinoma in dog.
abstract: The case of a 14-year-old mongrel dog with a thyroid tumor treated by thyreoidectomy is described. The resected tumor was subjected to a detailed morphological and immunohistochemical analysis utilizing antibodies directed against thyroglobulin, calcitonin, chromogranin A, cytokeratin 19, thyroid transcription factor-1, CD31, Ki-67 and minichromosome maintenance protein 3. Expression level of the above mentioned antigens allowed to characterize the resected tumor as thyroid follicular-compact carcinoma. Common application of immunohistochemistry may increase the diagnosis precision and efficacy of thyroid tumor treatment in dogs.
authors.forename: Rafal
authors.initials: R
authors.lastname: Ciaputa
authors.forename: Marcin
authors.initials: M
authors.lastname: Nowak
authors.forename: Malgorzata
authors.initials: M
authors.lastname: Kandefer-Gola
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Dziedzic
authors.forename: Pawel
authors.initials: P
authors.lastname: Halupka
authors.forename: Bartosz
authors.initials: B
authors.lastname: Pula
authors.forename: Maciej
authors.initials: M
authors.lastname: Kielbowicz
mesh_terms: D000818:Animals; D002116:Calcitonin / Q000235:genetics / Q000378:metabolism; D053379:Chromogranin A / Q000235:genetics / Q000378:metabolism; D004283:Dog Diseases / Q000378:metabolism* / Q000473:pathology; D004285:Dogs; D053539:Keratin-19 / Q000235:genetics / Q000378:metabolism; D019394:Ki-67 Antigen / Q000235:genetics / Q000378:metabolism; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000235:genetics / Q000378:metabolism; D013954:Thyroglobulin / Q000235:genetics / Q000378:metabolism; D013964:Thyroid Neoplasms / Q000662:veterinary*; D000074482:Thyroid Nuclear Factor 1; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism
chemical_list: D053379:Chromogranin A; D053539:Keratin-19; D019394:Ki-67 Antigen; D009687:Nuclear Proteins; D019408:Platelet Endothelial Cell Adhesion Molecule-1; D000074482:Thyroid Nuclear Factor 1; D014157:Transcription Factors; D002116:Calcitonin; D013954:Thyroglobulin