title: The role of tissue engineering in achilles tendon repair: a review.
abstract: Achilles tendon injuries are common but complex in nature. Healing occurs via scar tissue formation leading to poor patient outcomes. Currently surgical and non-surgical treatment leads to suboptimal tendon healing and has complications. Tissue engineering is an advancing field that can either augment surgical repair or provide an alternative method for Achilles tendon repair. This article will explore the principles behind tissue engineering in Achilles tendon repair. Furthermore it will describe the current literature regarding the different types of stem cells used in Achilles tendon repair, how different growth factors augment tendon repair, as well as the role of biomaterials in tissue engineering.
authors.forename: Varun
authors.initials: V
authors.lastname: Sahni
authors.forename: Saket
authors.initials: S
authors.lastname: Tibrewal
authors.forename: Lianne
authors.initials: L
authors.lastname: Bissell
authors.affiliation: 59 Elmstead Lane, Chislehurst, Kent BR7 5EQ. UK. sak11@hotmail.com.
authors.forename: Wasim S
authors.initials: WS
authors.lastname: Khan
mesh_terms: D000125:Achilles Tendon / Q000187:drug effects / Q000473:pathology*; D001672:Biocompatible Materials / Q000494:pharmacology; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000494:pharmacology; D033581:Stem Cell Transplantation; D013234:Stem Cells / Q000166:cytology / Q000187:drug effects; D023822:Tissue Engineering / Q000379:methods*; D014945:Wound Healing / Q000187:drug effects
chemical_list: D001672:Biocompatible Materials; D036341:Intercellular Signaling Peptides and Proteins