title: Experimental validation of 3D printed patient-specific implants using digital image correlation and finite element analysis.
abstract: With the dawn of 3D printing technology, patient-specific implant designs are set to have a paradigm shift. A topology optimization method in designing patient-specific craniofacial implants has been developed to ensure adequate load transfer mechanism and restore the form and function of the mid-face. Patient-specific finite element models are used to design these implants and to validate whether they are viable for physiological loading such as mastication. Validation of these topology optimized finite element models using mechanical testing is a critical step. Instead of inserting the implants into a cadaver or patient, we embed the implants into the computer-aided skull model of a patient and, fuse them together to 3D print the complete skull model with the implant. Masticatory forces are applied in the molar region to simulate chewing and measure the stress-strain trajectory. Until recently, strain gages have been used to measure strains for validation. Digital Image Correlation (DIC) method is a relatively new technique for full-field strain measurement which provides a continuous deformation field data. The main objective of this study is to validate the finite element model of patient-specific craniofacial implants against the strain data from the DIC obtained during the mastication simulation and show that the optimized shapes provide adequate load-transfer mechanism. Patient-specific models are obtained from CT scans. The principal maximum and minimum strains are compared. The computational and experimental approach to designing patient-specific implants proved to be a viable technique for mid-face craniofacial reconstruction.
authors.affiliation: Department of Plastic Surgery, The Ohio State University, Columbus, OH 43210, USA; Department of Mechanical and Aerospace Engineering, The Ohio State University, Columbus, OH 43210, USA. Electronic address: alok.sutradhar@osumc.edu.
authors.forename: Alok
authors.initials: A
authors.lastname: Sutradhar
authors.affiliation: Department of Mechanical and Aerospace Engineering, The Ohio State University, Columbus, OH 43210, USA.
authors.forename: Jaejong
authors.initials: J
authors.lastname: Park
authors.affiliation: College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
authors.forename: Diana
authors.initials: D
authors.lastname: Carrau
authors.affiliation: Department of Plastic Surgery, The Ohio State University, Columbus, OH 43210, USA.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Miller
mesh_terms: D020342:Finite Element Analysis; D006801:Humans; D008962:Models, Theoretical; D066330:Printing, Three-Dimensional; D012886:Skull / Q000033:anatomy & histology
keywords: Craniofacial implants; Digital image correlation; Masticatory simulation; Segmental bone defect; Topology optimization