title: Acute leukemia presenting as acute hepatitis without liver failure.
abstract: A diagnosis of acute lymphoblastic or myeloblastic leukemia was made in 6 children ages 4 to 14 years who presented with a clinicobiochemical picture of acute hepatitis without liver failure. Standard chemotherapy, including 1 week pretreatment with steroids in children with lymphoblastic leukemia, allowed complete remission of the leukemia and normalization of serum liver tests.
authors.affiliation: *Hépatologie Pédiatrique and Centre de Référence National de l'Atrésie des Voies Biliaires, Hôpital Bicêtre AP-HP, the INSERM U757 Orsay, and Université Paris-Sud 11, Le Kremlin-Bicêtre †Hématologie-Immuno-Oncologie Pédiatrique, Hôpital d'Enfants Armand Trousseau, AP-HP, Paris, France.
authors.forename: Christine
authors.initials: C
authors.lastname: Rivet
authors.forename: Guy
authors.initials: G
authors.lastname: Leverger
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Jacquemin
authors.forename: Olivier
authors.initials: O
authors.lastname: Bernard
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D006505:Hepatitis / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008099:Liver / Q000473:pathology*; D017093:Liver Failure; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D012074:Remission Induction
chemical_list: D000970:Antineoplastic Agents