title: New affinity-based probes for capturing flavonoid-binding proteins.
abstract: Flavonoid-bearing probes have been designed and synthesized to explore their ability to selectively capture target proteins or biosynthetic enzymes under oxidative activation. A proof-of-concept study using biotinylated (epi)catechin-bearing affinity-based probes herein demonstrates the ability of these probes to capture the LDOX flavonoid enzyme using sodium periodate as the oxidant.
authors.affiliation: Université de Bordeaux, Institut des Sciences Moléculaires (UMR-CNRS 5255), 2 rue Robert Escarpit, 33607 Pessac Cedex, France. denis.deffieux@u-bordeaux.fr.
authors.forename: Hélène
authors.initials: H
authors.lastname: Carrié
authors.forename: Dong Tien
authors.initials: DT
authors.lastname: Tran
authors.forename: Sabrina
authors.initials: S
authors.lastname: Rousseau
authors.forename: Stéphane
authors.initials: S
authors.lastname: Chaignepain
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Schmitter
authors.forename: Denis
authors.initials: D
authors.lastname: Deffieux
authors.forename: Stéphane
authors.initials: S
authors.lastname: Quideau
mesh_terms: D000345:Affinity Labels; D004591:Electrophoresis, Polyacrylamide Gel; D005419:Flavonoids / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry*
chemical_list: D000345:Affinity Labels; D005419:Flavonoids; D011506:Proteins