title: Epitope imprinted polyethersulfone beads by self-assembly for target protein capture from the plasma proteome.
abstract: Polymer self-assembly was developed as an epitope imprinting strategy involving facile processes and high recognition site density. As a model, transferrin epitope imprinted polyethersulfone (PES) beads were successfully fabricated using this technique. The imprinted beads demonstrated excellent selectivity toward the transferrin epitope and transferrin even in the real sample.
authors.affiliation: CAS Key Lab of Separation Sciences for Analytical Chemistry, National Chromatographic R&A Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China. lihuazhang@dicp.ac.cn.
authors.forename: Kaiguang
authors.initials: K
authors.lastname: Yang
authors.forename: Jianxi
authors.initials: J
authors.lastname: Liu
authors.forename: Senwu
authors.initials: S
authors.lastname: Li
authors.forename: Qinran
authors.initials: Q
authors.lastname: Li
authors.forename: Qi
authors.initials: Q
authors.lastname: Wu
authors.forename: Yuan
authors.initials: Y
authors.lastname: Zhou
authors.forename: Qun
authors.initials: Q
authors.lastname: Zhao
authors.forename: Nan
authors.initials: N
authors.lastname: Deng
authors.forename: Zhen
authors.initials: Z
authors.lastname: Liang
authors.forename: Lihua
authors.initials: L
authors.lastname: Zhang
authors.forename: Yukui
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000327:Adsorption; D000818:Animals; D000939:Epitopes / Q000737:chemistry*; D006801:Humans; D008863:Microspheres; D054802:Molecular Imprinting / Q000379:methods*; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry*; D020543:Proteome / Q000737:chemistry* / Q000276:immunology; D013450:Sulfones / Q000138:chemical synthesis* / Q000737:chemistry*; D014168:Transferrin / Q000737:chemistry* / Q000276:immunology
chemical_list: D000939:Epitopes; D011108:Polymers; D020543:Proteome; D013450:Sulfones; D014168:Transferrin; C022840:polyether sulfone