title: Highly stable antibacterial silver nanoparticles as selective fluorescent sensor for Fe³⁺ ions.
abstract: Calix[4]resorcinarene polyhydrazide (CPH) protected water dispersible fluorescent silver nanaoparticles (AgNps) were prepared by one-pot method using water soluble CPH and AgNO₃. (CPH) bearing hydrazide group on its periphery acts as a reducing agent and its web type of structure as a stabilizing agent for the formation of calix protected silver nanoparticles (CPH-AgNps). CPH-AgNps were found to be highly stable over 120 days at room temperature and at varied pH. CPH-AgNps were characterized by UV/Vis-spectroscopy, particle size analyzer (PSA), transmission electron microscopy (TEM) and Energy dispersive X-ray analysis (EDX). Duly characterized nanoparticles were explored for their application as sensitive and selective fluorescent chemosensors for various metal ions. It was found that nanoparticles were selective and sensitive only for Fe(3+) ions with the linear range of detection from 0.1 μM to 10 μM. CPH-AgNps were also found to exhibit good antimicrobial activity when compared with standard Chloramphenicol. The selectivity and antimicrobial activity of CPH-AgNps suggests its potential use as a sensor for Fe(III) ions in ecosystems prone to industrial pollution and as an antimicrobial agent in biological applications.
authors.affiliation: Department of Chemistry, School of Sciences, Gujarat University, Ahmedabad 380009, India.
authors.forename: Bharat A
authors.initials: BA
authors.lastname: Makwana
authors.affiliation: Department of Chemistry, School of Sciences, Gujarat University, Ahmedabad 380009, India.
authors.forename: Disha J
authors.initials: DJ
authors.lastname: Vyas
authors.affiliation: Department of Chemistry, School of Sciences, Gujarat University, Ahmedabad 380009, India.
authors.forename: Keyur D
authors.initials: KD
authors.lastname: Bhatt
authors.affiliation: Department of Chemistry, School of Sciences, Gujarat University, Ahmedabad 380009, India. Electronic address: drvkjain@hotmail.com.
authors.forename: Vinod K
authors.initials: VK
authors.lastname: Jain
authors.affiliation: Institute of Research & Development, Gujarat Forensic Sciences University, Gandhinagar 382007, Gujarat, India.
authors.forename: Yadvendra K
authors.initials: YK
authors.lastname: Agrawal
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D015374:Biosensing Techniques / Q000379:methods*; D047250:Calixarenes / Q000737:chemistry; D004355:Drug Stability; D005453:Fluorescence; D006863:Hydrogen-Ion Concentration; D007477:Ions; D007501:Iron / Q000032:analysis*; D057230:Limit of Detection; D053768:Metal Nanoparticles / Q000737:chemistry*; D008670:Metals / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D046529:Microscopy, Electron, Transmission; D012834:Silver / Q000737:chemistry*; D012835:Silver Nitrate / Q000737:chemistry; D013696:Temperature
chemical_list: D000900:Anti-Bacterial Agents; C000599839:Calix(4)resorcinarene polyhydrazide; D007477:Ions; D008670:Metals; D047250:Calixarenes; D012834:Silver; D012835:Silver Nitrate; D007501:Iron
keywords: Antibacterial; Calix[4]resorcinarene; Fluorescence; Polyhydrazide; Silver nanoparticles