title: Long-lasting changes in brain activation induced by a single REAC technology pulse in Wi-Fi bands. Randomized double-blind fMRI qualitative study.
abstract: The aim of this randomized double-blind study was to evaluate in healthy adult subjects, with functional magnetic resonance imaging (fMRI), long lasting changes in brain activation patterns following administration of a single, 250 milliseconds pulse emitted with radio-electric asymmetric conveyer (REAC) technology in the Wi-Fi bands. The REAC impulse was not administered during the scan, but after this, according to a protocol that has previously been demonstrated to be effective in improving motor control and postural balance, in healthy subjects and patients. The study was conducted on 33 healthy volunteers, performed with a 1.5 T unit while operating a motor block task involving cyclical and alternating flexion and extension of one leg. Subsequently subjects were randomly divided into a treatment and a sham treatment control group. Repeated fMRI examinations were performed following the administration of the REAC pulse or sham treatment. The Treated group showed cerebellar and ponto-mesencephalic activation components that disappeared in the second scan, while these activation components persisted in the Sham group. This study shows that a very weak signal, such as 250 milliseconds Wi-Fi pulse, administered with REAC technology, could lead to lasting effects on brain activity modification.
authors.affiliation: 1] Department of regenerative medicine, Rinaldi Fontani Institute, Viale Belfiore 43, 50144 Florence, Italy [2] Department of neuro psycho physical optimization, Rinaldi Fontani Institute, Viale Belfiore 43, 50144 Florence, Italy.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Rinaldi
authors.affiliation: Institute of Radiology, University of Cagliari, 09042 Monserrato, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Mura
authors.affiliation: 1] Department of regenerative medicine, Rinaldi Fontani Institute, Viale Belfiore 43, 50144 Florence, Italy [2] Department of neuro psycho physical optimization, Rinaldi Fontani Institute, Viale Belfiore 43, 50144 Florence, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Castagna
authors.affiliation: 1] Department of regenerative medicine, Rinaldi Fontani Institute, Viale Belfiore 43, 50144 Florence, Italy [2] Department of neuro psycho physical optimization, Rinaldi Fontani Institute, Viale Belfiore 43, 50144 Florence, Italy.
authors.forename: Vania
authors.initials: V
authors.lastname: Fontani
mesh_terms: D000328:Adult; D001921:Brain / Q000502:physiology*; D004311:Double-Blind Method; D004560:Electricity; D005260:Female; D006801:Humans; D020407:Internet; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D011846:Radio Waves; D055815:Young Adult