title: Management of life-threatening calcium channel blocker overdose with continuous veno-venous hemodiafiltration with charcoal hemoperfusion.
abstract: Cases of calcium channel blocker overdose reported from India are few, and although rare, they are associated with high mortality. Management includes fluids, vasopressors, calcium gluconate or chloride, glucagon infusion, and hyperinsulinemia-euglycemia therapy along with some rescue therapies tried in anecdotal reports. We report here a case of life-threatening overdose of amlodipine with shock, refractory to conventional therapies. Salvage therapy with continuous veno-venous hemodiafiltration using charcoal hemoperfusion with prior infusion of intravenous lipid emulsion resulted in a successful outcome.
authors.affiliation: Institute of Critical Care Medicine, Max Super Speciality Hospital, New Delhi, India.
authors.forename: Suneel K
authors.initials: SK
authors.lastname: Garg
authors.affiliation: Institute of Critical Care Medicine, Max Super Speciality Hospital, New Delhi, India.
authors.forename: Pankaj K
authors.initials: PK
authors.lastname: Goyal
authors.affiliation: Institute of Critical Care Medicine, Max Super Speciality Hospital, New Delhi, India.
authors.forename: Rahul
authors.initials: R
authors.lastname: Kumar
authors.affiliation: Institute of Critical Care Medicine, Max Super Speciality Hospital, New Delhi, India.
authors.forename: Deven
authors.initials: D
authors.lastname: Juneja
authors.affiliation: Institute of Critical Care Medicine, Max Super Speciality Hospital, New Delhi, India.
authors.forename: Alka
authors.initials: A
authors.lastname: Bhasin
authors.affiliation: Institute of Critical Care Medicine, Max Super Speciality Hospital, New Delhi, India.
authors.forename: Omender
authors.initials: O
authors.lastname: Singh
keywords: Amlodipine overdose; calcium channel blocker overdose; charcoal hemoperfusion; continuous veno-venous hemodiafiltration