title: Natural products containing 'decalin' motif in microorganisms.
abstract: Microorganisms are well-known producers of a wide variety of bioactive compounds that are utilized not only for their primary metabolism but also for other purposes such as defense, detoxification, or communication with other micro- and macro-organisms. Natural products containing a 'decalin ring' occur often in microorganisms. They exhibit diverse and remarkable biological activities, including antifungal, antibacterial, anticancer and immunosuppressive activities, to name a few. This review surveys the natural decalin-type compounds that have been isolated from microorganisms, with emphasis on both chemical and biological implications. Total syntheses of some important decalin moiety-containing natural products are also highlighted.
authors.affiliation: Institute of Environmental Research (INFU), Department of Chemistry and Chemical Biology, Chair of Environmental Chemistry and Analytical Chemistry, TU Dortmund, Otto-Hahn-Str.6, 44221 Dortmund, Germany. souvik.kusari@infu.tu-dortmund.de m.spiteller@infu.tu-dortmund.de.
authors.forename: Gang
authors.initials: G
authors.lastname: Li
authors.forename: Souvik
authors.initials: S
authors.lastname: Kusari
authors.forename: Michael
authors.initials: M
authors.lastname: Spiteller
mesh_terms: D000192:Actinomycetales / Q000737:chemistry*; D001688:Biological Products / Q000737:chemistry*; D005658:Fungi / Q000737:chemistry*; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry*
chemical_list: D001688:Biological Products; D009281:Naphthalenes; C007229:decalin