title: Performance and model of a novel multi-sparger multi-stage airlift loop membrane bioreactor to treat high-strength 7-ACA pharmaceutical wastewater: effect of hydraulic retention time, temperature and pH.
abstract: In this study, three novel multi-sparger multi-stage airlift loop membrane bioreactors (Ms(2)ALMBRs) were set up in parallel for treating synthetic high-strength 7-ACA pharmaceutical wastewater under different HRTs, temperatures and pHs, respectively. During the 200-day operating time, average COD removal efficiencies were 94.96%, 96.05% and 93.9%. While average 7-ACA removal efficiencies were 66.44%, 59.04% and 59.60%, respectively. The optimal conditions were 10h, 15-35°C and 7-9 for HRT, temperature and pH, respectively. Moreover, the sludge characteristics and microorganism drug-resistances were explored. Results showed that different temperatures and pHs influenced contaminant removals by affecting MLSS concentration and β-lactamase activity significantly. In addition, mathematical statistical models, built on the polynomial and linear regression techniques, were developed for exploring the inner relationships between HRT, temperature and pH changes and MLSS concentrations, β-lactamase activities and contaminant removals of the Ms(2)ALMBR system.
authors.affiliation: College of Environment and Resources, Dalian Nationalities University, 18 Liaohe West Road, Dalian 116600, China. Electronic address: czbhdx@163.com.
authors.forename: Zhao-bo
authors.initials: ZB
authors.lastname: Chen
authors.affiliation: School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China.
authors.forename: Zhang-wei
authors.initials: ZW
authors.lastname: He
authors.affiliation: School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China.
authors.forename: Cong-cong
authors.initials: CC
authors.lastname: Tang
authors.affiliation: College of Environment and Resources, Dalian Nationalities University, 18 Liaohe West Road, Dalian 116600, China.
authors.forename: Dong-xue
authors.initials: DX
authors.lastname: Hu
authors.affiliation: College of Environment and Resources, Dalian Nationalities University, 18 Liaohe West Road, Dalian 116600, China.
authors.forename: Yu-bo
authors.initials: YB
authors.lastname: Cui
authors.affiliation: School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China.
authors.forename: Ai-jie
authors.initials: AJ
authors.lastname: Wang
authors.affiliation: College of Resources and Environment, Northeast Agricultural University, Harbin 150030, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: College of Resources and Environment, Northeast Agricultural University, Harbin 150030, China.
authors.forename: Li-long
authors.initials: LL
authors.lastname: Yan
authors.affiliation: School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China.
authors.forename: Nan-qi
authors.initials: NQ
authors.lastname: Ren
mesh_terms: D001673:Biodegradation, Environmental; D019149:Bioreactors; D002511:Cephalosporins / Q000302:isolation & purification*; D006863:Hydrogen-Ion Concentration; D008567:Membranes, Artificial; D008962:Models, Theoretical; D004364:Pharmaceutical Preparations / Q000302:isolation & purification; D013696:Temperature; D013997:Time Factors; D062065:Wastewater / Q000737:chemistry*; D018508:Water Purification / Q000295:instrumentation* / Q000379:methods*
chemical_list: D002511:Cephalosporins; D008567:Membranes, Artificial; D004364:Pharmaceutical Preparations; D062065:Wastewater; C030735:7-aminocephalosporanic acid
keywords: Mathematical statistical model; Microorganism drug-resistances; Multi-sparger multi-stage airlift loop membrane bioreactor (Ms(2)ALMBR); Sludge characteristics; Synthetic high-strength 7-ACA pharmaceutical wastewater