title: Palladium-catalyzed synthesis of isoindoloquinazolinones via dicarbonylation of 1,2-dibromoarenes.
abstract: A convenient procedure for the carbonylative synthesis of isoindoloquinazolinones has been developed. Using 1,2-dibromobenzenes and 2-aminobenzyl amine as substrates and palladium as the catalyst, the desired products were isolated in moderate to good yields with the installation of two molecules of carbon monoxide. Notably, this is the first example of carbonylative synthesis of batracylin analogues.
authors.affiliation: Leibniz-Institut für Katalyse an der Universität Rostock, Albert-Einstein-Straße 29a, 18059 Rostock, Germany. xiao-feng.wu@catalysis.de.
authors.forename: Jianbin
authors.initials: J
authors.lastname: Chen
authors.forename: Helfried
authors.initials: H
authors.lastname: Neumann
authors.forename: Matthias
authors.initials: M
authors.lastname: Beller
authors.forename: Xiao-Feng
authors.initials: XF
authors.lastname: Wu
mesh_terms: D002254:Carbonates / Q000737:chemistry*; D002384:Catalysis; D008401:Gas Chromatography-Mass Spectrometry; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D011799:Quinazolines / Q000737:chemistry; D052999:Quinazolinones / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D002254:Carbonates; D006842:Hydrocarbons, Brominated; D011799:Quinazolines; D052999:Quinazolinones; D010165:Palladium; C057924:batracylin