title: [The development of C-C cross-coupling reaction of monocarba-closo-dodecaborate anion for the synthesis of functional molecules].
abstract: A cross-coupling reaction at the carbon vertex of a monocarba-closo-dodecaborate has been developed to allow introduction of various aryl groups and other sp(2)/sp-hybridized carbon centers. A copper(I) complex facilitated the coupling process with a wide range of electrophiles at room temperature. The reaction was successfully used to prepare a series of C-arylated caborane anion derivatives, some of which showed potent androgen-receptor binding activity and excellent mesogenic properties.
authors.affiliation: Graduate School of Pharmaceutical Sciences, The University of Tokyo.
authors.forename: Junichiro
authors.initials: J
authors.lastname: Kanazawa
authors.forename: Ryo
authors.initials: R
authors.lastname: Takita
authors.forename: Masanobu
authors.initials: M
authors.lastname: Uchiyama
mesh_terms: D000838:Anions / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D002254:Carbonates / Q000737:chemistry*; D003300:Copper / Q000737:chemistry; D003432:Cross-Linking Reagents / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy
chemical_list: D000838:Anions; D002254:Carbonates; D003432:Cross-Linking Reagents; D002244:Carbon; D003300:Copper