title: Meckel's Diverticulum: Factors Associated with Clinical Manifestations.
abstract: Objectives. The purpose of this study was to investigate the clinical features of Meckel's diverticula at different ages, genders, and pathology in order to serve as a reminder to clinicians when evaluating potential cases and to help obtain an early diagnosis. Methods. We collected information of patients with Meckel's diverticulum diagnosed at Mackay Memorial Hospital in Taiwan from 1984 to 2009. After performing a thorough review of their charts, the clinical features of the Meckel's diverticula were analyzed according to age groups, gender, and pathology. Result. A total of 126 patients, with 90 males and 36 females, were enrolled in this study. Seventy-five patients were symptomatic and 51 Meckel's diverticula were found incidentally during surgery for other diseases. Among symptomatic patients, 39% of pediatric patients and 5% of adult patients had intestinal hemorrhage. Twenty-eight percent of pediatric patients and 67% of adult patients had inflammation of Meckel's diverticulum. Forty-six percent of males and 16% of females had inflammation. Conversely, 27% of males and 58% percent of females had intestinal obstruction. When Meckel's diverticulum had ectopic gastric mucosa, it tended to cause intestinal hemorrhage when the patient is young. Conclusions. Age, gender, and pathology affect the clinical presentations of Meckel's diverticula.
authors.affiliation: Department of Pediatrics, Mackay Memorial hospital, Hsinchu, Taiwan.
authors.forename: Jeng-Jung
authors.identifier: 0000-0002-7756-7123
authors.initials: JJ
authors.lastname: Chen
authors.affiliation: Department of Pediatrics, Mackay Memorial hospital, Hsinchu, Taiwan ; Department of Pediatrics, Taipei Medical University, Taipei, Taiwan.
authors.forename: Hung-Chang
authors.initials: HC
authors.lastname: Lee
authors.affiliation: Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan ; Mackay Medicine, Nursing and Management College, Taipei, Taiwan.
authors.forename: Chun-Yan
authors.identifier: 0000-0001-8582-927X
authors.initials: CY
authors.lastname: Yeung
authors.affiliation: Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Wai-Tao
authors.initials: WT
authors.lastname: Chan
authors.affiliation: Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Chuen-Bin
authors.initials: CB
authors.lastname: Jiang
authors.affiliation: Department of Pediatric Surgery, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Jin-Cherng
authors.initials: JC
authors.lastname: Sheu
authors.affiliation: Department of Pediatric Surgery, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Nein-Lu
authors.initials: NL
authors.lastname: Wang