title: Motor task performance under vibratory feedback early poststroke: single center, randomized, cross-over, controlled clinical trial.
abstract: Stroke rehabilitation is far from meeting patient needs in terms of timing, intensity and quality. This study evaluates the efficacy and safety of an innovative technological tool, combining 3D motion analysis with targeted vibratory feedback, on upper-limb task performance early poststroke (<4 weeks). The study design was a two-sequence, two-period, randomized, crossover trial (NCT01967290) in 44 patients with upper-limb motor deficit (non-plegic) after medial cerebral artery ischemia. Participants were randomly assigned to receive either the experimental session (repetitive motor task under vibratory feedback and 3D motor characterization) or the active comparator (3D motor characterization only). The primary outcome was the number of correct movements per minute on a hand-to-mouth task measured independently. Vibratory feedback was able to modulate motor training, increasing the number of correct movements by an average of 7.2/min (95%CI [4.9;9.4]; P < 0.001) and reducing the probability of performing an error from 1:3 to 1:9. This strategy may improve the efficacy of training on motor re-learning processes after stroke, and its clinical relevance deserves further study in longer duration trials.
authors.affiliation: 1] Neurology Department, Hospital São Sebastião, Centro Hospitalar Entre Douro e Vouga, Rua Dr Cândido de Pinho, 4520-211 Santa Maria da Feira, Portugal [2] Clinical Research Office, Health Sciences Department, University of Aveiro, Portugal.
authors.forename: Vítor Tedim
authors.initials: VT
authors.lastname: Cruz
authors.affiliation: 1] Neurology Department, Hospital São Sebastião, Centro Hospitalar Entre Douro e Vouga, Rua Dr Cândido de Pinho, 4520-211 Santa Maria da Feira, Portugal [2] Maia Institute of Higher Education, Maia, Portugal.
authors.forename: Virgílio
authors.initials: V
authors.lastname: Bento
authors.affiliation: Neurology Department, Hospital São Sebastião, Centro Hospitalar Entre Douro e Vouga, Rua Dr Cândido de Pinho, 4520-211 Santa Maria da Feira, Portugal.
authors.forename: Luís
authors.initials: L
authors.lastname: Ruano
authors.affiliation: Neurology Department, Hospital São Sebastião, Centro Hospitalar Entre Douro e Vouga, Rua Dr Cândido de Pinho, 4520-211 Santa Maria da Feira, Portugal.
authors.forename: David Dieteren
authors.initials: DD
authors.lastname: Ribeiro
authors.affiliation: Neurology Department, Hospital São Sebastião, Centro Hospitalar Entre Douro e Vouga, Rua Dr Cândido de Pinho, 4520-211 Santa Maria da Feira, Portugal.
authors.forename: Luís
authors.initials: L
authors.lastname: Fontão
authors.affiliation: Neurology Department, Hospital São Sebastião, Centro Hospitalar Entre Douro e Vouga, Rua Dr Cândido de Pinho, 4520-211 Santa Maria da Feira, Portugal.
authors.forename: Cátia
authors.initials: C
authors.lastname: Mateus
authors.affiliation: Neurology Department, Hospital São Sebastião, Centro Hospitalar Entre Douro e Vouga, Rua Dr Cândido de Pinho, 4520-211 Santa Maria da Feira, Portugal.
authors.forename: Rui
authors.initials: R
authors.lastname: Barreto
authors.affiliation: Neurology Department, Hospital São Sebastião, Centro Hospitalar Entre Douro e Vouga, Rua Dr Cândido de Pinho, 4520-211 Santa Maria da Feira, Portugal.
authors.forename: Márcio
authors.initials: M
authors.lastname: Colunas
authors.affiliation: Rehabilitation Department, Hospital São Sebastião, Centro Hospitalar Entre Douro e Vouga, Santa Maria da Feira, Portugal.
authors.forename: Ana
authors.initials: A
authors.lastname: Alves
authors.affiliation: Rehabilitation Department, Hospital Sra. da Oliveira, Centro Hospitalar do Alto Ave, Guimarães, Portugal.
authors.forename: Bárbara
authors.initials: B
authors.lastname: Cruz
authors.affiliation: Rehabilitation Department, Hospital São Sebastião, Centro Hospitalar Entre Douro e Vouga, Santa Maria da Feira, Portugal.
authors.forename: Catarina
authors.initials: C
authors.lastname: Branco
authors.affiliation: Clinical Research Office, Health Sciences Department, University of Aveiro, Portugal.
authors.forename: Nelson P
authors.initials: NP
authors.lastname: Rocha
authors.affiliation: UnIGENe, Instituto de Biologia Molecular e Celular, University of Porto, Portugal.
authors.forename: Paula
authors.initials: P
authors.lastname: Coutinho
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018592:Cross-Over Studies; D005246:Feedback; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D009068:Movement / Q000502:physiology; D020127:Recovery of Function / Q000502:physiology*; D020521:Stroke / Q000503:physiopathology*; D013647:Task Performance and Analysis; D013997:Time Factors; D034941:Upper Extremity / Q000502:physiology