title: Regioselective SN2' Mitsunobu reaction of Morita-Baylis-Hillman alcohols: A facile and stereoselective synthesis of α-alkylidene-β-hydrazino acid derivatives.
abstract: A highly regioselective SN2' Mitsunobu reaction between Morita-Baylis-Hillman (MBH) alcohols, azodicarboxylates, and triphenylphosphine is developed, which provides an easy access to α-alkylidene-β-hydrazino acid derivatives in high yields and good stereoselectivity. This reaction represents the first direct transformation of MBH alcohols into hydrazines.
authors.affiliation: Department of Chemistry, School of Science, Xi'an Jiaotong University, Xi'an 710049, P. R. China.
authors.forename: Silong
authors.initials: S
authors.lastname: Xu
authors.affiliation: Department of Chemistry, School of Science, Xi'an Jiaotong University, Xi'an 710049, P. R. China.
authors.forename: Jian
authors.initials: J
authors.lastname: Shang
authors.affiliation: Department of Chemistry, School of Science, Xi'an Jiaotong University, Xi'an 710049, P. R. China.
authors.forename: Junjie
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Chemistry, School of Science, Xi'an Jiaotong University, Xi'an 710049, P. R. China.
authors.forename: Yuhai
authors.initials: Y
authors.lastname: Tang
keywords: Mitsunobu reaction; Morita–Baylis–Hillman; SN2' reaction; azodicarboxylate; hydrazine