title: Magnetic resonance standard for cavernous sinus hemangiomas: proposal for a diagnostic test.
abstract: BACKGROUND
  By definition, a cavernous sinus is a vascular plexus. A hemangioma is a vascular tumor which is rich in vascular plexus and caused by vascular deformity or tumor-like proliferation. Radiosurgery can effectively control the growth of smaller cavernous sinus hemangiomas (CSHs). This paper aimed to quantify the MRI characteristics of CSHs which provided a basis for further treatment.
  
  
  METHODS
  A retrospective analysis was conducted of the MRI characteristics of 133 cavernous sinus lesion patients between January 2006 and December 2009, and none of them was diagnosed without histology. Two groups were set apart according to the pathological results: a CSH group (24 patients) and a non-CSH group (109 patients). The latter was further divided into 3 categories: a meningioma group (33 patients), a neurilemmoma group (37 patients) and a miscellaneous group (39 patients). A single-factor χ(2) analysis was performed to analyze the data on the 12 MRI characteristics.
  
  
  RESULTS
  T2-weighted ultrahigh signal, signal uniformity, dumbbell-like appearance and infiltration of the sellar region were considered statistically significant for the differentiation of CSHs from non-CSHs. If these 4 items served as the diagnostic criteria, the sensitivity, specificity and accuracy was 87.5, 96.3 and 94.7%, respectively.
  
  
  CONCLUSIONS
  Smaller CSHs can be treated by radiosurgery directly, without performance of a pathological biopsy.
authors.affiliation: Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
authors.forename: Kangmin
authors.initials: K
authors.lastname: He
authors.forename: Liang
authors.initials: L
authors.lastname: Chen
authors.forename: Wei
authors.initials: W
authors.lastname: Zhu
authors.forename: Ying
authors.initials: Y
authors.lastname: Mao
mesh_terms: D002426:Cavernous Sinus / Q000473:pathology*; D016543:Central Nervous System Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D020786:Hemangioma, Cavernous, Central Nervous System / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008579:Meningioma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D009442:Neurilemmoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D012189:Retrospective Studies; D012680:Sensitivity and Specificity