title: Early diagnosis of lip cancer preceded by a persistent actinic lesion in a kidney transplant patient: a case report.
abstract: Lip cancer is 65 times more likely to occur in kidney transplant patients than in members of the general population. Immunosuppression drugs taken by the transplant patients have been associated with this increased occurrence. This case report shows the progression from actinic cheilosis to squamous cell carcinoma (SCC) in the lower lip of a 58-year-old man receiving immunosuppressive therapy 9 years after undergoing a kidney transplant. Earlier incisional biopsies had resulted in a histological diagnosis of actinic cheilosis. However, the last incisional biopsy showed histological results compatible with SCC, and oncological surgery was performed. Eight months post-surgery, the patient was free of cancer and metastasis. Frequent dental follow-up visits allowed for the early diagnosis, proper treatment, and an improved prognosis for this patient.
authors.forename: Francisco Artur Forte
authors.initials: FA
authors.lastname: Oliveira
authors.forename: Clarissa Pessoa
authors.initials: CP
authors.lastname: Fernandes
authors.forename: Ana Paula Negreiros Nunes
authors.initials: AP
authors.lastname: Alves
authors.forename: Mario Rogerio Lima
authors.initials: MR
authors.lastname: Mota
authors.forename: Paula Frassinetti Castelo Branco Camurca
authors.initials: PF
authors.lastname: Fernandes
authors.forename: Fabricio Bitu
authors.initials: FB
authors.lastname: Sousa
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000175:diagnosis*; D002613:Cheilitis / Q000150:complications*; D042241:Early Diagnosis; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D016030:Kidney Transplantation; D008048:Lip Neoplasms / Q000150:complications / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged
chemical_list: D007166:Immunosuppressive Agents