title: A phosphine-mediated stereocontrolled synthesis of Z-enediynes by a vicinal dialkynylation of ethynylphosphonium salts.
abstract: Z-Enediynes are prepared by a vicinal dialkynylation of triaryl(arylethynyl)phosphonium cations. The method, which proceeds under mild transition metal-free conditions, can be conducted on multigram scale as a one-pot, phosphine-mediated synthetic cycle giving enediyne products with excellent control of configuration.
authors.affiliation: Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA. radosevich@psu.edu.
authors.forename: Kyle D
authors.initials: KD
authors.lastname: Reichl
authors.forename: Alexander T
authors.initials: AT
authors.lastname: Radosevich