title: Two cases of esophageal eosinophilia: eosinophilic esophagitis or gastro-esophageal reflux disease?
abstract: Eosinophilic esophagitis (EoE) and gastroesophageal reflux disease are among the major causes of isolated esophageal eosinophilia. Isolated esophageal eosinophilia meeting criteria for EoE may respond to proton pump inhibitor (PPI) treatment. This entity is termed proton pumps inhibitor responsive esophageal eosinophilia (PPI-REE). Gastro-esophageal reflux is thought to comprise a subgroup of patients with PPI-REE. According to the latest guidelines, PPI responsiveness distinguishes people with PPI-REE from patients having EoE (non-responders). In this report, two unusual cases with findings belonging to both EoE and PPI-REE are discussed with known and unknown facts.
authors.affiliation: Department of Pediatric Allergy and Asthma, Gazi University School of Medicine , Ankara, Turkey.
authors.forename: Ozlem
authors.initials: O
authors.lastname: Yilmaz
authors.affiliation: Department of Pediatric Allergy and Asthma, Gazi University School of Medicine , Ankara, Turkey.
authors.forename: Hacer Ilbilge Ertoy
authors.initials: HI
authors.lastname: Karagol
authors.affiliation: Department of Pediatric Allergy and Asthma, Gazi University School of Medicine , Ankara, Turkey.
authors.forename: Erdem
authors.initials: E
authors.lastname: Topal
authors.affiliation: Department of Pediatric Gastroenterology, Gazi University School of Medicine , Ankara, Turkey.
authors.forename: Aysel Aksu
authors.initials: AA
authors.lastname: Unlusoy
authors.affiliation: Department of Pediatric Gastroenterology, Gazi University School of Medicine , Ankara, Turkey.
authors.forename: Odul
authors.initials: O
authors.lastname: Egritas
authors.affiliation: Department of Pathology, Gazi University School of Medicine , Ankara, Turkey.
authors.forename: Ipek Isik
authors.initials: II
authors.lastname: Gonul
authors.affiliation: Department of Pediatric Allergy and Asthma, Gazi University School of Medicine , Ankara, Turkey.
authors.forename: Arzu
authors.initials: A
authors.lastname: Bakirtas
keywords: children; eosinophils; esophagitis; proton pumps inhibitors