title: Stereoselective total synthesis of cytospolide P.
abstract: A short and convergent stereoselective total synthesis of biologically potent cytospolide P has been accomplished from acrolein. The salient features of our synthetic strategy include modified Crimmins aldols, Yamaguchi esterification, and Grubbs ring-closing metathesis reaction.
authors.affiliation: Department of Organic Chemistry, Indian Association for the Cultivation of Science , Jadavpur, Kolkata-700032, India.
authors.forename: Shamba
authors.initials: S
authors.lastname: Chatterjee
authors.forename: Sandip
authors.initials: S
authors.lastname: Guchhait
authors.forename: Rajib Kumar
authors.initials: RK
authors.lastname: Goswami
mesh_terms: D000171:Acrolein / Q000737:chemistry*; D003500:Cyclization; D004951:Esterification; D018942:Macrolides / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D018942:Macrolides; C000595171:cytospolide P; D000171:Acrolein