title: Er:Yb:NaY2F5O up-converting nanoparticles for sub-tissue fluorescence lifetime thermal sensing.
abstract: Non-contact thermometry is essential in biomedical studies requiring thermal sensing and imaging with high thermal and spatial resolutions. In this work, we report the potential use of Er:Yb:NaYF4 and Er:Yb:NaY2F5O up-conversion nanoparticles as thermal sensors by means of lifetime based luminescent thermometry. We demonstrate how Er:Yb:NaY2F5O nanocrystals present a higher thermal sensitivity than the Er:Yb:NaYF4 ones and that their lifetime thermal coefficient is comparable to those corresponding to other nano-sized luminescent systems already used for high resolution lifetime fluorescence thermal sensing. We evaluate the potential use of Er:Yb:NaY2F5O nanoparticles as lifetime based thermal probes by providing the first experimental evidence on sub-tissue lifetime fluorescence thermal sensing by using up-conversion nanoparticles in an ex vivo experiment.
authors.affiliation: Física i Cristal.lografia de Materials i Nanomaterials (FiCMA-FiCNA)- EMaS, Universitat Rovira i Virgili (URV), Campus Sescelades, C/ Marcel.li Domingo s/n, E-43007, Tarragona, Spain. joanjosep.carvajal@urv.cat.
authors.forename: Ol A
authors.initials: OA
authors.lastname: Savchuk
authors.forename: P
authors.initials: P
authors.lastname: Haro-González
authors.forename: J J
authors.initials: JJ
authors.lastname: Carvajal
authors.forename: D
authors.initials: D
authors.lastname: Jaque
authors.forename: J
authors.initials: J
authors.lastname: Massons
authors.forename: M
authors.initials: M
authors.lastname: Aguiló
authors.forename: F
authors.initials: F
authors.lastname: Díaz
mesh_terms: D005456:Fluorescent Dyes / Q000737:chemistry*; D005459:Fluorides / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D008674:Metals, Rare Earth / Q000737:chemistry*; D010316:Particle Size; D013696:Temperature
chemical_list: D005456:Fluorescent Dyes; D008674:Metals, Rare Earth; D005459:Fluorides