title: Challenges of infectious diseases in the USA.
abstract: In the USA, infectious diseases continue to exact a substantial toll on health and health-care resources. Endemic diseases such as chronic hepatitis, HIV, and other sexually transmitted infections affect millions of individuals and widen health disparities. Additional concerns include health-care-associated and foodborne infections--both of which have been targets of broad prevention efforts, with success in some areas, yet major challenges remain. Although substantial progress in reduction of the burden of vaccine-preventable diseases has been made, continued cases and outbreaks of these diseases persist, driven by various contributing factors. Worldwide, emerging and reemerging infections continue to challenge prevention and control strategies while the growing problem of antimicrobial resistance needs urgent action. An important priority for control of infectious disease is to ensure that scientific and technological advances in molecular diagnostics and bioinformatics are well integrated into public health. Broad and diverse partnerships across governments, health care, academia, and industry, and with the public, are essential to effectively reduce the burden of infectious diseases.
authors.affiliation: Office of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: rfk1@cdc.gov.
authors.forename: Rima F
authors.initials: RF
authors.lastname: Khabbaz
authors.affiliation: Office of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Robin R
authors.initials: RR
authors.lastname: Moseley
authors.affiliation: Division of Adolescent and School Health, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Riley J
authors.initials: RJ
authors.lastname: Steiner
authors.affiliation: Office of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Alexandra M
authors.initials: AM
authors.lastname: Levitt
authors.affiliation: National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Beth P
authors.initials: BP
authors.lastname: Bell
mesh_terms: D000818:Animals; D003140:Communicable Disease Control / Q000379:methods; D003141:Communicable Diseases / Q000453:epidemiology*; D004199:Disease Vectors; D004352:Drug Resistance, Microbial; D015658:HIV Infections / Q000453:epidemiology / Q000517:prevention & control; D006521:Hepatitis, Chronic / Q000453:epidemiology / Q000517:prevention & control; D006801:Humans; D015994:Incidence; D015995:Prevalence; D011634:Public Health / Q000592:standards / Q000639:trends; D012749:Sexually Transmitted Diseases / Q000453:epidemiology / Q000517:prevention & control; D014376:Tuberculosis / Q000453:epidemiology / Q000517:prevention & control; D014481:United States / Q000453:epidemiology; D014611:Vaccination; D015047:Zoonoses / Q000453:epidemiology / Q000517:prevention & control