title: [Acid stress response of Salmonella and its relationship with virulence--a review].
abstract: As successful enteric bacteria, Salmonella spp. has to overcome the extreme acid condition in the stomach before invading into host intestinal epithelial cells. Salmonella spp. has evolved an adaptation to its replicative niche in the acidic environment. This review summarizes acid resistant characteristics of Salmonella, and introduces several mechanisms to acid resistance, including keeping internal pH homeostatic, synthesizing acid shock protein through several regulatory pathways and altering membrane character. The achievements will be significant for understanding and controlling Salmonella infections in the future.
authors.forename: Jie
authors.initials: J
authors.lastname: Ren
authors.forename: Mingwen
authors.initials: M
authors.lastname: Zhao
authors.forename: Yufeng
authors.initials: Y
authors.lastname: Yao
mesh_terms: D000143:Acids / Q000378:metabolism*; D000222:Adaptation, Physiological; D000818:Animals; D006801:Humans; D012475:Salmonella / Q000472:pathogenicity* / Q000502:physiology*; D012480:Salmonella Infections / Q000382:microbiology*; D014774:Virulence
chemical_list: D000143:Acids