title: Palladium-catalyzed oxidative CH/CH cross-coupling of pyridine N-oxides with five-membered heterocycles.
abstract: Using Ag2CO3 as an additive, we developed the Pd-catalyzed intermolecular C-H/C-H cross-coupling of pyridine N-oxides with five-membered heterocycles such as 1-benzyl-1,2,3-triazoles, thiophens and furans. This protocol provides an efficient and regioselective approach for the synthesis of unsymmetrical biheteroaryl molecules.
authors.affiliation: Department of Chemistry, Tongji University, Siping Road 1239, Shanghai 200092, China. kuangcx@tongji.edu.cn.
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.forename: Xin
authors.initials: X
authors.lastname: Yu
authors.forename: Yahui
authors.initials: Y
authors.lastname: Li
authors.forename: Chunxiang
authors.initials: C
authors.lastname: Kuang
mesh_terms: D002384:Catalysis; D006571:Heterocyclic Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*
chemical_list: D006571:Heterocyclic Compounds; D010087:Oxides; D011725:Pyridines; D010165:Palladium; C023666:pyridine