title: Monocyte-plasmablast crosstalk during dengue.
abstract: Dengue virus infection induces a dramatic expansion of B cell plasmablasts. In this issue, Kwissa et al. (2014) begin with transcriptomic analysis and then integrate studies in human clinical samples, nonhuman primates, and coculture of primary human cells to identify a role for CD14(+)CD16(+) monocytes in generating plasmablast responses during dengue virus infection.
authors.affiliation: Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA 94720-3370, USA.
authors.forename: Angela M
authors.initials: AM
authors.lastname: Green
authors.affiliation: Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA 94720-3370, USA. Electronic address: eharris@berkeley.edu.
authors.forename: Eva
authors.initials: E
authors.lastname: Harris
mesh_terms: D000818:Animals; D049109:Cell Proliferation; D003715:Dengue / Q000276:immunology*; D003716:Dengue Virus / Q000276:immunology*; D006801:Humans; D018950:Lipopolysaccharide Receptors / Q000032:analysis*; D009000:Monocytes / Q000276:immunology*; D010950:Plasma Cells / Q000502:physiology*; D017452:Receptors, IgG / Q000032:analysis*
chemical_list: D018950:Lipopolysaccharide Receptors; D017452:Receptors, IgG