title: Novel [4 + 2]-benzannulation to access substituted benzenes and polycyclic aromatic and benzene-fused heteroaromatic compounds.
abstract: A common [4 + 2]-benzannulation of Morita-Baylis-Hillman acetates of acetylenic aldehydes with boronic acids has been developed for the synthesis of aromatic and heteroaromatic compounds through tandem allylic substitution/hydroarylative cycloisomerization process. This method provides a facile and general route to substituted benzenes, naphthalenes, other polycyclic aromatics, and various benzene-fused heteroaromatic compounds such as benzofuran, benzothiophene, indole, and carbazoles.
authors.affiliation: Division of Natural Products Chemistry, CSIR-Indian Institute of Chemical Technology , Hyderabad 500607, India.
authors.forename: Chada
authors.initials: C
authors.lastname: Raji Reddy
authors.forename: Uredi
authors.initials: U
authors.lastname: Dilipkumar
authors.forename: Motatipally
authors.initials: M
authors.lastname: Damoder Reddy