title: A cascade alkylarylation reaction of 2-isocyanobiphenyls with simple alkanes for 6-alkyl phenanthridines via dual C(sp3)-H/C(sp2)-H functionalizations.
abstract: A cascade alkylarylation reaction of 2-isocyanobiphenyls with simple alkanes for 6-alkyl phenanthridines has been developed through dual C(sp(3))-H/C(sp(2))-H functionalizations. The synthetic method has the advantages of high yields, good compatibility of functional groups and mild reaction conditions, although very unreactive alkanes were involved in the reaction. A plausible mechanism through both copper-catalyzed and DTBP mediated pathways has also been proposed.
authors.affiliation: Department of Chemistry, Zhejiang University, Xixi Campus, Hangzhou 310028, P. R. China. huangzhizhen@zju.edu.cn.
authors.forename: Zhi-Qiang
authors.initials: ZQ
authors.lastname: Zhu
authors.forename: Tian-Tian
authors.initials: TT
authors.lastname: Wang
authors.forename: Peng
authors.initials: P
authors.lastname: Bai
authors.forename: Zhi-Zhen
authors.initials: ZZ
authors.lastname: Huang