title: Anti-aquaporin-4 antibody-positive dorsal midbrain syndrome.
abstract: Neuromyelitis optica spectrum disorders (NMOSD) can cause various ocular motor disorders in addition to optic neuritis. Ocular motor findings associated with NMOSD include spontaneous vertical and gaze-evoked nystagmus, wall-eyed bilateral internuclear ophthalmoplegia, and trochlear nerve palsy. The association between dorsal midbrain syndrome and anti-aquaporin-4 antibody seropositivity has not been reported. Here, we report a patient displaying typical dorsal midbrain syndrome and anti-aquaporin-4 antibody seropositivity.
authors.affiliation: Chungnam National University Hospital, Daejeon, Korea.
authors.forename: Juyoun
authors.initials: J
authors.lastname: Lee
authors.affiliation: Chungnam National University Hospital, Daejeon, Korea mseaj@hanmail.net.
authors.forename: Seong-Hae
authors.initials: SH
authors.lastname: Jeong
authors.affiliation: Chungnam National University Hospital, Daejeon, Korea.
authors.forename: Sang Min
authors.initials: SM
authors.lastname: Park
authors.affiliation: Chungnam National University Hospital, Daejeon, Korea.
authors.forename: Eun Hee
authors.initials: EH
authors.lastname: Sohn
authors.affiliation: Chungnam National University Hospital, Daejeon, Korea.
authors.forename: Ae Young
authors.initials: AY
authors.lastname: Lee
authors.affiliation: Chungnam National University Hospital, Daejeon, Korea.
authors.forename: Jae-Moon
authors.initials: JM
authors.lastname: Kim
authors.affiliation: Chungnam National University Hospital, Daejeon, Korea.
authors.forename: Hyun-Jin
authors.initials: HJ
authors.lastname: Jo
authors.affiliation: Chungnam National University Hospital, Daejeon, Korea.
authors.forename: Yeon-Hee
authors.initials: YH
authors.lastname: Lee
authors.affiliation: Seoul National Bundang Hospital, Seongnam, Korea.
authors.forename: Ji-Soo
authors.initials: JS
authors.lastname: Kim
mesh_terms: D051401:Aquaporin 4 / Q000276:immunology; D001323:Autoantibodies / Q000097:blood / Q000276:immunology; D001324:Autoantigens / Q000276:immunology; D001927:Brain Diseases / Q000276:immunology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008636:Mesencephalon / Q000473:pathology*; D008875:Middle Aged; D009471:Neuromyelitis Optica / Q000276:immunology / Q000503:physiopathology*; D013577:Syndrome
chemical_list: C496030:AQP4 protein, human; D051401:Aquaporin 4; D001323:Autoantibodies; D001324:Autoantigens
keywords: Dorsal midbrain syndrome; aquaporin-4; neuromyelitis optica