title: Antiepileptic drugs for neuropathic pain and fibromyalgia.
abstract: OBJECTIVE
  Are antiepileptic drugs associated with reduced pain intensity in patients with neuropathic pain or fibromyalgia?
  
  
  CONCLUSIONS
  In treating diabetic neuropathy and postherpetic neuralgia compared with placebo, gabapentin and pregabalin are associated with a modest increase in the number of patients experiencing meaningful pain reduction. In treating fibromyalgia, compared with placebo, pregabalin alone is associated with a small increase in the number of patients experiencing meaningful pain reduction. There is insufficient evidence for other antiepileptics.
authors.affiliation: Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, England.
authors.forename: Andrew
authors.initials: A
authors.lastname: Moore
authors.affiliation: Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, England.
authors.forename: Philip
authors.initials: P
authors.lastname: Wiffen
authors.affiliation: Department of Anaesthesia, Intensive Care Medicine, Emergency Medicine, and Pain Medicine, Helsinki University Central Hospital, Helsinki, Finland3Institute of Clinical Medicine, University of Helsinki, Finland.
authors.forename: Eija
authors.initials: E
authors.lastname: Kalso
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use*; D005356:Fibromyalgia / Q000188:drug therapy*; D006801:Humans; D009437:Neuralgia / Q000188:drug therapy*
chemical_list: D000927:Anticonvulsants