title: The use of negative pressure in critical necrotizing fasciitis treatment: a case presentation.
abstract: Surgery complemented by antibiotics forms the backbone of the successful management of necrotizing fasciitis. But it will be very difficult to clear away extensive necrotizing tissue thoroughly in critically ill patients when their vital signs are unstable. The authors report the case of a 33-year-old woman who had extensive necrotizing fasciitis of the right lower limb with septic shock. The patient was severely anemic and malnutrition and had been given conservative debridement at bedside, that is, only detached necrotizing tissues was taken away while some other necrotizing tissue still remained, so that the skin tissue within the same area could be saved as much as possible. After debridement, negative pressure was applied at 125 mm Hg. Broad-spectrum antibiotics and effective supplementation were also complemented, thus controlling the septic shock. All necrotizing tissues were detached, and the sparing vital skin on necrotizing fascia was preserved successfully after negative pressure treatment. The patient was finally saved. In conclusion, negative pressure treatment may help diminish toxin absorbance, detach gangrene tissue, and preserve sparing vital tissue. This case suggests the value of combined use of negative pressure therapy and conservative debridement in critically ill patients with extensive necrotizing fasciitis.
authors.affiliation: Shanghai 9th People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Kui
authors.initials: K
authors.lastname: Ge
authors.affiliation: Shanghai 9th People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Bing
authors.initials: B
authors.lastname: Xu
authors.affiliation: Shanghai 9th People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Jia-Jun
authors.initials: JJ
authors.lastname: Wu
authors.affiliation: Shanghai 9th People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Minjie
authors.initials: M
authors.lastname: Wu
authors.affiliation: Shanghai 9th People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Shuliang
authors.initials: S
authors.lastname: Lu
authors.affiliation: Shanghai 9th People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China 13564350034@139.com.
authors.forename: Ting
authors.initials: T
authors.lastname: Xie
mesh_terms: D000328:Adult; D016638:Critical Illness; D019115:Fasciitis, Necrotizing / Q000628:therapy*; D005260:Female; D006801:Humans; D054843:Negative-Pressure Wound Therapy
keywords: critical ill patient; necrotizing fasciitis; negative pressure treatment; wound debridement