title: Iron-catalyzed, chelation-induced remote C-H allylation of quinolines via 8-amido assistance.
abstract: An iron-catalyzed, 8-amido-enabled regiodivergent C-H allylation of quinolines is described. This reaction represents a rare example of chelation-induced geometrically inaccessible C-H functionalization, allowing for the highly regio- and stereoselective preparation of either the C5- or the C4-allylated quinoline scaffolds regiocontrolled by the catalytic systems.
authors.affiliation: Center for Organic Chemistry, Frontier Institute of Science and Technology, Xi'an Jiaotong University , Xi'an, Shaanxi, 710054, P. R. China.
authors.forename: Xuefeng
authors.initials: X
authors.lastname: Cong
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Zeng
mesh_terms: D000577:Amides / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D015394:Molecular Structure; D011804:Quinolines / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000577:Amides; D011804:Quinolines; D007501:Iron