title: Optimizing prostate specimen handling for diagnosis and prognosis.
abstract: Optimal processing, handling, and sampling of prostatic biopsies, transurethral resections, and radical prostatectomy specimens ensure accurate diagnosis and staging. Prognostic factors derived from careful examination of tissue samples are critical for patient management, including cancer volume, extraprostatic extension, surgical margins, vascular/lymphatic invasion, and perineural invasion. This chapter addresses these important issues, including recent recommendations of a consensus panel of the International Society of Urologic Pathologists.
authors.affiliation: Bostwick Laboratories, 7001 Lake Ellenor Dr, Orlando, FL, 32809, USA, dbostwick@bostwicklaboratories.com.
authors.forename: David G
authors.initials: DG
authors.lastname: Bostwick
authors.forename: Christina E
authors.initials: CE
authors.lastname: Day
authors.forename: Isabelle
authors.initials: I
authors.lastname: Meiers
mesh_terms: D001706:Biopsy / Q000379:methods*; D062005:Biopsy, Large-Core Needle; D006801:Humans; D008297:Male; D011379:Prognosis; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D020728:Transurethral Resection of Prostate