title: Examining the utility of using genotype and functional biology in a clinical pharmacology trial: pilot testing dopamine β-hydroxylase, norepinephrine, and post-traumatic stress disorder.
authors.affiliation: aNeurorehabilitation: Neurons to Networks Traumatic Brain Injury Center of Excellence, Michael E. DeBakey Veterans Affairs (VA) Medical Center (MEDVAMC) bMenninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas cDepartment of Veterans Affairs, South Central Mental Illness, Research, Education and Clinical Center (MIRECC), Houston, Texas dTuscaloosa VA Medical Center (TVAMC), Tuscaloosa eDepartment of Psychiatry, University of Alabama School of Medicine, Birmingham, Alabama fRalph H. Johnson VA Medical Center (RHJVAMC), Medical University of South Carolina, Charleston, South Carolina gDepartment of Psychiatry, James J. Peters VA Medical Center (JJPVAMC), Bronx hIchan School of Medicine at Mount Sinai, New York, New York, USA.
authors.forename: David P
authors.initials: DP
authors.lastname: Graham
authors.forename: David A
authors.initials: DA
authors.lastname: Nielsen
authors.forename: Thomas R
authors.initials: TR
authors.lastname: Kosten
authors.forename: Lori L
authors.initials: LL
authors.lastname: Davis
authors.forename: Mark B
authors.initials: MB
authors.lastname: Hamner
authors.forename: Iouri
authors.initials: I
authors.lastname: Makotkine
authors.forename: Rachel
authors.initials: R
authors.lastname: Yehuda
mesh_terms: D002986:Clinical Trials as Topic; D004299:Dopamine beta-Hydroxylase / Q000235:genetics*; D005838:Genotype; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use*; D009638:Norepinephrine / Q000378:metabolism*; D010865:Pilot Projects; D013313:Stress Disorders, Post-Traumatic / Q000188:drug therapy* / Q000201:enzymology / Q000235:genetics*; D013871:Thiones / Q000627:therapeutic use*
chemical_list: D007093:Imidazoles; D013871:Thiones; D004299:Dopamine beta-Hydroxylase; C109487:nepicastat; D009638:Norepinephrine