title: Chronic Venous Disease and Comorbidities.
abstract: We report the relations between comorbidities and chronic venous disease. In this cross-sectional study, information was gathered from 1679 Serbian patients. The majority (65.0%) of patients were women. Mild forms of chronic venous disease (clinical, etiologic, anatomic and pathophysiologic [CEAP] classification; C0s-C1) were more frequent in women (11.6%), while severe forms (CEAP C4-C6) were more commonly encountered in men (42.1%). The most frequent comorbidity was emphysema/chronic obstructive pulmonary disease in both groups (74.3% in males and 70.6% in females). For females, diabetes mellitus (P < .005), arterial hypertension (P < .000), and skeletal/joint diseases (P < .042) were more commonly found in the C4 to C6 category. Both males and females, with severe form of chronic venous disease, may benefit from additional screening for comorbidities. Further studies are needed to clarify the nature of association among comorbidities and chronic venous disease.
authors.affiliation: Cardiovascular Institute Dedinje, School of Medicine, University of Belgrade, Belgrade, Serbia.
authors.forename: P
authors.initials: P
authors.lastname: Matic
authors.affiliation: Department of Dermatology, Medical Centre Kikinda, Kikinda, Serbia.
authors.forename: S
authors.initials: S
authors.lastname: Jolic
authors.affiliation: Cardiovascular Institute Dedinje, School of Medicine, University of Belgrade, Belgrade, Serbia.
authors.forename: S
authors.initials: S
authors.lastname: Tanaskovic
authors.affiliation: Faculty of Medicine, Institute of Medical Statistics and Informatics, University of Belgrade, Belgrade, Serbia.
authors.forename: I
authors.initials: I
authors.lastname: Soldatovic
authors.affiliation: Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece.
authors.forename: N
authors.initials: N
authors.lastname: Katsiki
authors.affiliation: Laboratory of Radiobiology and Molecular Genetics, Institute Vinca, University of Belgrade, Belgrade, Serbia isenovic@yahoo.com.
authors.forename: E
authors.initials: E
authors.lastname: Isenovic
authors.affiliation: Cardiovascular Institute Dedinje, School of Medicine, University of Belgrade, Belgrade, Serbia.
authors.forename: Dj
authors.initials: Dj
authors.lastname: Radak
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D015897:Comorbidity; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D055771:Serbia / Q000453:epidemiology; D012720:Severity of Illness Index; D017678:Sex Distribution; D012737:Sex Factors; D014648:Varicose Veins / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D014689:Venous Insufficiency / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D055815:Young Adult
keywords: anatomic and pathophysiologic classification; chronic venous disease; clinical; comorbidity; etiologic