title: Invasive ductal carcinoma of the breast in a 14-year-old girl.
abstract: Breast cancer is rare in children and adolescents. In particular, there are very few cases of invasive ductal carcinoma in childhood. We report a case of invasive ductal carcinoma of the breast in a 14-year-old girl presenting as a palpable mass. While the tumor demonstrated a relatively benign appearance on ultrasound, magnetic resonance imaging revealed typical malignant features. Several polymorphisms of single nucleotide variation were observed on gene analysis. The patient underwent breast conserving surgery and received subsequent concurrent chemo-radiation therapy. An awareness that ductal carcinoma of the breast rarely occurs in children is important to detect early stage breast cancer.
authors.affiliation: Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-Gu, Seoul, Korea.
authors.forename: Joo Yeon
authors.initials: JY
authors.lastname: Kim
authors.forename: Yun Ju
authors.initials: YJ
authors.lastname: Kim
authors.forename: Sung Hun
authors.initials: SH
authors.lastname: Kim
authors.forename: Bong Joo
authors.initials: BJ
authors.lastname: Kang
authors.forename: Byung Joo
authors.initials: BJ
authors.lastname: Song
mesh_terms: D000293:Adolescent; D001943:Breast Neoplasms / Q000235:genetics / Q000473:pathology* / Q000628:therapy*; D018270:Carcinoma, Ductal, Breast / Q000235:genetics / Q000473:pathology* / Q000628:therapy*; D059186:Chemoradiotherapy, Adjuvant; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D008279:Magnetic Resonance Imaging; D015412:Mastectomy, Segmental; D009367:Neoplasm Staging; D035583:Rare Diseases / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D016217:Ultrasonography, Mammary