title: Comparison of diagnostic methods for evaluation of postmenopausal bleeding.
abstract: OBJECTIVE
  To determine and compare diagnostic accuracy parameters of saline infusion sonohysterography (SIS), transvaginal ultrasonography (TVUSG), and hysteroscopy (H/S) based on histopathologic results which are accepted to be the gold standard in patients with postmenopausal bleeding (PMB).
  
  
  METHODS
  Forty-seven patients who applied to Gynecology clinic of Adnan Menderes University, School of Medicine with PMB complaint aged between 43-76 years were included to the study. Fractioned curettage (F/C) and H/S guided biopsy were used for endometrial sampling. Diagnostic accuracy parameters (sensitivity, specificity, and positive and negative predictive values) of different methods; TVUSG, SIS, and H/S based on histopathologic findings were investigated.
  
  
  RESULTS
  Specificity and sensitivity values calculated based on histopathologic results for all endometrial cavity lesions were found, respectively: 44.4% and 25% for TVUSG, 88.8% and 60.7% for SIS, and 100% and 77.7% for HIS.
  
  
  CONCLUSIONS
  SIS is superior to TVUSG and as effective as H/S for assessment of endometrial cavity lesions in patients with PMB.
authors.forename: S
authors.initials: S
authors.lastname: Nergiz
authors.forename: S
authors.initials: S
authors.lastname: Demircan-Sezer
authors.forename: M
authors.initials: M
authors.lastname: Küçük
authors.forename: H
authors.initials: H
authors.lastname: Yüksel
authors.forename: A R
authors.initials: AR
authors.lastname: Odabaşi
authors.forename: S O
authors.initials: SO
authors.lastname: Altinkaya
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D008875:Middle Aged; D017698:Postmenopause; D014463:Ultrasonography; D014592:Uterine Hemorrhage / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D014621:Vagina / Q000000981:diagnostic imaging