title: Turning cell cycle entry on its head.
abstract: New data on the relationship between two proteins, cyclin D and Rb, suggest that we need to re-evaluate our understanding of how cells enter into the cell cycle.
authors.affiliation: Cosetta Bertoli is at the MRC Laboratory for Molecular Cell Biology, University College London, London, United Kingdom.
authors.forename: Cosetta
authors.initials: C
authors.lastname: Bertoli
authors.affiliation: Robertus Antonius Maria de Bruin is at the MRC Laboratory for Molecular Cell Biology, University College London, London, United Kingdom r.debruin@ucl.ac.uk.
authors.forename: Robertus Antonius Maria
authors.initials: RA
authors.lastname: de Bruin
mesh_terms: D000818:Animals; D019938:Cyclin D1 / Q000378:metabolism*; D006801:Humans; D016160:Retinoblastoma Protein / Q000378:metabolism*
chemical_list: D016160:Retinoblastoma Protein; D019938:Cyclin D1
keywords: CDK; DNA replication stress; G1/S transcription; cell cycle; checkpoint; genome integrity