title: Triflic acid-promoted cycloisomerization of 2-alkynylphenyl isothiocyanates and isocyanates: a novel synthetic method for a variety of indole derivatives.
abstract: A new approach towards the synthesis of indole derivatives via triflic acid-promoted cycloisomerization with rearrangement of 2-(alkyn-1-yl)phenyl isothiocyanates and 2-(alkyn-1-yl)phenyl isocyanates has been achieved. By this methodology, structurally diverse types of indole derivatives such as thieno- and furo-indoles, spiro-indolethiones, spiro-oxindoles, and 3-alkylidene-oxindoles were synthesized.
authors.affiliation: Department of Chemistry, Faculty of Science, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan. tsaito@rs.kagu.tus.ac.jp totani@rs.tus.ac.jp.
authors.forename: Takao
authors.initials: T
authors.lastname: Saito
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Sonoki
authors.forename: Takashi
authors.initials: T
authors.lastname: Otani
authors.forename: Noriki
authors.initials: N
authors.lastname: Kutsumura
mesh_terms: D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis*; D017953:Isocyanates / Q000737:chemistry*; D007536:Isomerism; D017879:Isothiocyanates / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D008958:Models, Molecular
chemical_list: D007211:Indoles; D017953:Isocyanates; D017879:Isothiocyanates; D008698:Mesylates; C005441:phenylisothiocyanate; C012077:trifluoromethanesulfonic acid