title: Optoelectrical microfluidics as a promising tool in biology.
abstract: Noncontact robotic particle grippers with trapping, manipulation, and release functions are highly desired in cell biology and microfluidics. Optoelectric techniques combine optical and electrokinetic effects to create thousands of such individually addressable traps. By projecting reconfigurable light patterns, these techniques can concentrate molecules, as well as manipulate, sort, and electroporate cells in a programmable manner. We describe the underlying physical mechanisms and discuss applications in biology and future prospects of these devices.
authors.affiliation: Birck Nanotechnology Center, School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA.
authors.forename: Avanish
authors.initials: A
authors.lastname: Mishra
authors.affiliation: Birck Nanotechnology Center, School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA.
authors.forename: Jae-Sung
authors.initials: JS
authors.lastname: Kwon
authors.affiliation: Birck Nanotechnology Center, School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA.
authors.forename: Raviraj
authors.initials: R
authors.lastname: Thakur
authors.affiliation: Birck Nanotechnology Center, School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA. Electronic address: wereley@purdue.edu.
authors.forename: Steve
authors.initials: S
authors.lastname: Wereley
mesh_terms: D000818:Animals; D035843:Biomedical Research; D002469:Cell Separation; D002478:Cells, Cultured; D055664:Electrochemical Techniques; D018274:Electroporation; D006801:Humans; D051379:Mice; D046210:Microfluidic Analytical Techniques; D052898:Optical Tweezers; D055095:Optics and Photonics; D010777:Photochemistry; D013552:Swine
keywords: cell manipulation; electrokinetics; microfluidics; optical tweezers; optofluidics; patterning