title: Management of heparin-induced thrombocytopenia with fondaparinux in a patient with left ventricular assist device.
abstract: Heparin-induced thrombocytopenia is an immune-mediated serious adverse effect of heparin therapy. It is a relatively frequent complication among patients with mechanical circulatory support. Herein, we present a patient with severe heart failure and sepsis who developed heparin-induced thrombocytopenia shortly after implantation of left ventricular assist device as a bridge to transplantation and who was successfully treated with fondaparinux.
authors.affiliation: Department for Cardiovascular Diseases, University Hospital Centre Zagreb, Croatia.
authors.forename: V
authors.initials: V
authors.lastname: Velagic
authors.affiliation: Department for Cardiovascular Diseases, University Hospital Centre Zagreb, Croatia ; University of Zagreb School of Medicine, Zagreb, Croatia.
authors.forename: J
authors.initials: J
authors.lastname: Samardzic
authors.affiliation: Department for Cardiovascular Diseases, University Hospital Centre Zagreb, Croatia.
authors.forename: Z
authors.initials: Z
authors.lastname: Baricevic
authors.affiliation: Department for Cardiovascular Diseases, University Hospital Centre Zagreb, Croatia ; University of Zagreb School of Medicine, Zagreb, Croatia.
authors.forename: B
authors.initials: B
authors.lastname: Skoric
authors.affiliation: Department for Cardiovascular Diseases, University Hospital Centre Zagreb, Croatia ; University of Zagreb School of Medicine, Zagreb, Croatia.
authors.forename: M
authors.initials: M
authors.lastname: Cikes
authors.affiliation: University of Zagreb School of Medicine, Zagreb, Croatia ; Department of Cardiac Surgery, University Hospital Centre Zagreb, Croatia.
authors.forename: H
authors.initials: H
authors.lastname: Gasparovic
authors.affiliation: University of Zagreb School of Medicine, Zagreb, Croatia ; Department of Cardiac Surgery, University Hospital Centre Zagreb, Croatia.
authors.forename: B
authors.initials: B
authors.lastname: Biocina
authors.affiliation: Department for Cardiovascular Diseases, University Hospital Centre Zagreb, Croatia ; University of Zagreb School of Medicine, Zagreb, Croatia.
authors.forename: D
authors.initials: D
authors.lastname: Milicic
keywords: Anticoagulation; Heart failure; Heparin-induced thrombocytopenia; Sepsis; Ventricular assist device