title: Anti-TNF-α therapy in patients with refractory uveitis due to Behçet's disease: a 1-year follow-up study of 124 patients.
abstract: OBJECTIVE
  The aim of this study was to assess the efficacy of anti-TNF-α therapy in refractory uveitis due to Behçet's disease (BD).
  
  
  METHODS
  We performed a multicentre study of 124 patients with BD uveitis refractory to conventional treatment including high-dose corticosteroids and at least one standard immunosuppressive agent. Patients were treated for at least 12 months with infliximab (IFX) (3-5 mg/kg at 0, 2 and 6 weeks and then every 4-8 weeks) or adalimumab (ADA) (usually 40 mg every 2 weeks). The main outcome measures were degree of anterior and posterior chamber inflammation, visual acuity, macular thickness and immunosuppression load.
  
  
  RESULTS
  Sixty-eight men and 56 women (221 affected eyes) were studied. The mean age was 38.6 years (s.d. 10.4). HLA-B51 was positive in 66.1% of patients and uveitis was bilateral in 78.2%. IFX was the first biologic agent in 77 cases (62%) and ADA was first in 47 (38%). In most cases anti-TNF-α drugs were used in combination with conventional immunosuppressive drugs. At the onset of anti-TNF-α therapy, anterior chamber and vitreous inflammation was observed in 57% and 64.4% of patients, respectively. In both conditions the damage decreased significantly after 1 year. At baseline, 50 patients (80 eyes) had macular thickening [optical coherence tomography (OCT) >250 μm] and 35 (49 eyes) had cystoid macular oedema (OCT>300 μm) that improved from 420 μm (s.d. 119.5) at baseline to 271 μm (s.d. 45.6) at month 12 (P < 0.01). The best-corrected visual acuity and the suppression load also showed significant improvement. After 1 year of follow-up, 67.7% of patients were inactive. Biologic therapy was well tolerated in most cases.
  
  
  CONCLUSIONS
  Anti-TNF-α therapy is effective and relatively safe in refractory BD uveitis.
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Vanesa
authors.initials: V
authors.lastname: Calvo-Río
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Ricardo
authors.initials: R
authors.lastname: Blanco
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Emma
authors.initials: E
authors.lastname: Beltrán
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Juán
authors.initials: J
authors.lastname: Sánchez-Bursón
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Marina
authors.initials: M
authors.lastname: Mesquida
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Alfredo
authors.initials: A
authors.lastname: Adán
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: María Victoria
authors.initials: MV
authors.lastname: Hernandez
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Marisa
authors.initials: M
authors.lastname: Hernandez Garfella
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Elia
authors.initials: E
authors.lastname: Valls Pascual
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Lucía
authors.initials: L
authors.lastname: Martínez-Costa
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Agustí
authors.initials: A
authors.lastname: Sellas-Fernández
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Miguel
authors.initials: M
authors.lastname: Cordero Coma
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Manuel
authors.initials: M
authors.lastname: Díaz-Llopis
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Roberto
authors.initials: R
authors.lastname: Gallego
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: David
authors.initials: D
authors.lastname: Salom
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: José L
authors.initials: JL
authors.lastname: García Serrano
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Norberto
authors.initials: N
authors.lastname: Ortego
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: José M
authors.initials: JM
authors.lastname: Herreras
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Alejandro
authors.initials: A
authors.lastname: Fonollosa
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Angel M
authors.initials: AM
authors.lastname: García-Aparicio
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Olga
authors.initials: O
authors.lastname: Maíz
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Ana
authors.initials: A
authors.lastname: Blanco
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Ignacio
authors.initials: I
authors.lastname: Torre
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Cruz
authors.initials: C
authors.lastname: Fernández-Espartero
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Vega
authors.initials: V
authors.lastname: Jovani
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Diana
authors.initials: D
authors.lastname: Peiteado-Lopez
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Esperanza
authors.initials: E
authors.lastname: Pato
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Juan
authors.initials: J
authors.lastname: Cruz
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Carlos
authors.initials: C
authors.lastname: Fernández-Cid
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Elena
authors.initials: E
authors.lastname: Aurrecoechea
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Miriam
authors.initials: M
authors.lastname: García
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Caracuel
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Carlos
authors.initials: C
authors.lastname: Montilla
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Antonio
authors.initials: A
authors.lastname: Atanes
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Félix Francisco
authors.initials: FF
authors.lastname: Hernandez
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Santos
authors.initials: S
authors.lastname: Insua
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Senén
authors.initials: S
authors.lastname: González-Suárez
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Amalia
authors.initials: A
authors.lastname: Sánchez-Andrade
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Fernando
authors.initials: F
authors.lastname: Gamero
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Luis
authors.initials: L
authors.lastname: Linares
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Fredeswinda
authors.initials: F
authors.lastname: Romero-Bueno
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: A Javier
authors.initials: AJ
authors.lastname: García
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Raquel
authors.initials: R
authors.lastname: Almodovar
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Enrique
authors.initials: E
authors.lastname: Minguez
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Carmen
authors.initials: C
authors.lastname: Carrasco Cubero
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Alejandro
authors.initials: A
authors.lastname: Olive
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Julio
authors.initials: J
authors.lastname: Vázquez
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Oscar
authors.initials: O
authors.lastname: Ruiz Moreno
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Fernando
authors.initials: F
authors.lastname: Jiménez-Zorzo
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Javier
authors.initials: J
authors.lastname: Manero
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Santiago
authors.initials: S
authors.lastname: Muñoz Fernández
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Javier
authors.initials: J
authors.lastname: Rueda-Gotor
authors.affiliation: Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Rheumatology, Hospital General Universitario de Valencia, Valencia, Rheumatology, Hospital de Valme, Sevilla, Ophthalmology and Rheumatology, Hospital Clinic, Barcelona, Ophthalmology, Hospital General Universitario de Valencia, Rheumatology and Ophthalmology, Hospital Peset Valencia, Valencia, Rheumatology Hospital Val d'Hebron, Barcelona, Ophthalmology Division, Hospital de León, Ophthalmology, Hospital Universitario La Fe, Valencia, Ophthalmology and Autoimmune Diseases, Hospital San Cecilio, Granada, Ophthalmology, Hospital Universitario, IOBA, Valladolid, Ophthalmology, Hospital de Cruces, Bilbao, Rheumatology, Hospital de Toledo, Rheumatology and Ophthalmology, Hospital Donosti San Sebastian, Rheumatology, Hospital Basurto, Bilbao, Rheumatology, Hospital Universitario de Móstoles, Rheumatology, Hospital General de Alicante, Rheumatology, Hospital Universitario La Paz Madrid, Rheumatology, Hospital Clínico San Carlos, Madrid, Rheumatology and Ophthalmology, Hospital de Pontevedra, Rheumatology, Hospital Sierrallana, Torrelavega, Rheumatology, Hospital La Princesa, Madrid, Rheumatology, Hospital de Córdoba, Rheumatology, Hospital Universitario de Salamanca, Rheumatology, HUCA La Coruña, Rheumatology, Hospital Doctor Negrín Canarias, Rheumatology, Hospital Universitario Santiago de Compostela, A Coruña, Rheumatology, Hospital Cabueñes, Gijón, Rheumatology, Hospital Lucus Augusti, Lugo, Rheumatology, Hospital San Pedro Alcantara, Caceres, Rheumatology, Hospital Arrixaca, Murcia, Rheumatology, Fundación Jiménez Díaz, Rheumatology, Hospital 12 de Octubre, Madrid, Rheumatology, Hospital Universitario Fundación Alcorcon, Ophthalmology, Hospital Clínico de Zaragoza, Rheumatology, Hospital de Merida, Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Rheumatology, Hospital de Ferrol, A Coruña, Ophthalmology, Rheumatology Hospital Miguel Servet, Zaragoza, and 
authors.forename: Miguel A
authors.initials: MA
authors.lastname: González-Gay
mesh_terms: D000068879:Adalimumab; D000293:Adolescent; D000328:Adult; D000368:Aged; D000911:Antibodies, Monoclonal / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D061067:Antibodies, Monoclonal, Humanized / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001528:Behcet Syndrome / Q000150:complications / Q000188:drug therapy*; D001688:Biological Products / Q000009:adverse effects / Q000627:therapeutic use; D002648:Child; D004334:Drug Administration Schedule; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D000069285:Infliximab; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*; D014605:Uveitis / Q000188:drug therapy* / Q000209:etiology; D055815:Young Adult
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D001688:Biological Products; D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D014409:Tumor Necrosis Factor-alpha; D000069285:Infliximab; D000068879:Adalimumab; D011241:Prednisone
keywords: Behçet’s disease; anti-TNF therapy; uveitis