title: Neurofeedback training of gamma band oscillations improves perceptual processing.
abstract: In this study, a noninvasive electroencephalography-based neurofeedback method is applied to train volunteers to deliberately increase gamma band oscillations (40 Hz) in the visual cortex. Gamma band oscillations in the visual cortex play a functional role in perceptual processing. In a previous study, we were able to demonstrate that gamma band oscillations prior to stimulus presentation have a significant influence on perceptual processing of visual stimuli. In the present study, we aimed to investigate longer lasting effects of gamma band neurofeedback training on perceptual processing. For this purpose, a feedback group was trained to modulate oscillations in the gamma band, while a control group participated in a task with an identical design setting but without gamma band feedback. Before and after training, both groups participated in a perceptual object detection task and a spatial attention task. Our results clearly revealed that only the feedback group but not the control group exhibited a visual processing advantage and an increase in oscillatory gamma band activity in the pre-stimulus period of the processing of the visual object stimuli after the neurofeedback training. Results of the spatial attention task showed no difference between the groups, which underlines the specific role of gamma band oscillations for perceptual processing. In summary, our results show that modulation of gamma band activity selectively affects perceptual processing and therefore supports the relevant role of gamma band activity for this specific process. Furthermore, our results demonstrate the eligibility of gamma band oscillations as a valuable tool for neurofeedback applications.
authors.affiliation: Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany, n.salari@uke.de.
authors.forename: Neda
authors.initials: N
authors.lastname: Salari
authors.forename: Christian
authors.initials: C
authors.lastname: Büchel
authors.forename: Michael
authors.initials: M
authors.lastname: Rose
mesh_terms: D000328:Adult; D001288:Attention / Q000502:physiology*; D004569:Electroencephalography / Q000379:methods; D005074:Evoked Potentials, Visual / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D058765:Neurofeedback / Q000502:physiology*; D010775:Photic Stimulation / Q000379:methods; D014793:Visual Cortex / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*