title: Intraoperative complications have a negative impact on postoperative outcomes after rectal cancer surgery.
abstract: OBJECTIVE
  The impact of intraoperative complications on the postoperative outcome in rectal cancer surgery is only poorly studied in literature. Thus, the aim of the present study was to assess the frequency of intraoperative complications during rectal resections for malignancies and its influence on the short term outcome.
  
  
  METHODS
  We analyzed 605 consecutive patients, who had operations for rectal cancer at a single institution between 1995 and 2010. Retrospective data from the surgical procedure and postoperative course were obtained from the institutional colorectal database and individual chart reviews. Intraoperative complications were recorded and its influence on postoperative course was investigated.
  
  
  RESULTS
  Intraoperative complications occurred in 66 (10.9%) patients, with injury to the spleen (n = 35 of 66, 53%) being the most frequent complication. Patients with intraoperative complications had a significant longer hospital stay (median: 13 days, range 7-92) compared to patients without complications (median: 12 days, range 2-135; p = 0.0102). In addition, intraoperative complications showed a tendency towards an increased risk for postoperative surgical complications (p = 0.0536), whereas no impact on postoperative medical complications could be found (p = 0.8043). Pulmonary disorders were the only predictive marker for intraoperative complications (p = 0.0247) by univariate analysis.
  
  
  CONCLUSIONS
  We found that intraoperative complications during rectal cancer surgery significantly prolonged hospital length stay. The overall morbidity rate was not affected.
authors.affiliation: Medical University of Vienna, Austria, Department of General Surgery, Währinger Gürtel 18-20, A-1090 Vienna, Austria. Electronic address: stefan.riss@meduniwien.ac.at.
authors.forename: Stefan
authors.initials: S
authors.lastname: Riss
authors.affiliation: Center for Medical Statistics, Informatics, and Intelligent Systems, Austria.
authors.forename: Martina
authors.initials: M
authors.lastname: Mittlböck
authors.affiliation: Medical University of Vienna, Austria, Department of General Surgery, Währinger Gürtel 18-20, A-1090 Vienna, Austria.
authors.forename: Katharina
authors.initials: K
authors.lastname: Riss
authors.affiliation: York Teaching Hospital NHS Foundation Trust, UK.
authors.forename: Praminthra
authors.initials: P
authors.lastname: Chitsabesan
authors.affiliation: Medical University of Vienna, Austria, Department of General Surgery, Währinger Gürtel 18-20, A-1090 Vienna, Austria.
authors.forename: Anton
authors.initials: A
authors.lastname: Stift
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007431:Intraoperative Complications; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology; D012004:Rectal Neoplasms / Q000601:surgery*; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome
keywords: Complications; Rectal cancer; Rectal resection; Surgery