title: Diagnostic and functional imaging of thymic and mediastinal involvement in lymphoproliferative disorders.
abstract: Lymphoproliferative disorders of the anterior mediastinum may involve the thymus or lymph nodes as part of disseminated disease or as an isolated site. Imaging is crucial in managing patients with mediastinal lymphoma and is employed in pretreatment assessment, midtreatment evaluation of response, posttreatment restaging, and surveillance during follow-up. For decades, computed tomography (CT) has been the standard imaging technique, although in the last years, positron emission tomography (PET)-CT and magnetic resonance imaging (MRI) have been introduced. We discuss the role of different imaging techniques in the assessment of patients with mediastinal lymphoma, focusing on novel aspects of PET-CT and diffusion-weighted/MRI.
authors.affiliation: Department of Radiology, San Luigi Gonzaga University Hospital, Orbassano, Torino, Italy. Electronic address: adriano.priola@inwind.it.
authors.forename: Adriano Massimiliano
authors.initials: AM
authors.lastname: Priola
authors.affiliation: Department of Emergency Medicine, Johns Hopkins Bayview Medical Center, Baltimore, MD, USA.
authors.forename: Giorgio
authors.initials: G
authors.lastname: Galetto
authors.affiliation: Department of Radiology, San Luigi Gonzaga University Hospital, Orbassano, Torino, Italy.
authors.forename: Sandro Massimo
authors.initials: SM
authors.lastname: Priola
mesh_terms: D003937:Diagnosis, Differential; D003952:Diagnostic Imaging / Q000379:methods*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology; D008223:Lymphoma / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008477:Mediastinal Diseases / Q000175:diagnosis*; D008479:Mediastinal Neoplasms / Q000473:pathology; D008482:Mediastinum / Q000000981:diagnostic imaging / Q000473:pathology; D064847:Multimodal Imaging / Q000379:methods; D049268:Positron-Emission Tomography / Q000379:methods; D019275:Radiopharmaceuticals; D013950:Thymus Gland / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: (18)F-FDG/PET–CT; Computed tomography; Lymphoma; Magnetic resonance imaging; Thymus