title: Biopsy of uterine leiomyomata and frozen sections before laparoscopic morcellation.
abstract: Uterine sarcoma is rare. However, its morcellation can be associated with spread of disease. The definitive diagnosis of uterine sarcomas is made via histology. To date, the only reliable preoperative test for determination of the types of myometrial tumors is analysis of either frozen sections or permanent formalin-fixed tissue sections of surgical specimens. We report 2 cases in which the feasibility of obtaining multiple biopsy specimens of uterine leiomyomas and frozen sections before laparoscopic morcellation is demonstrated. This procedure might reduce the risk of laparoscopic morcellation of unsuspected leiomyosarcomas while still offering the advantages of a minimally invasive technique.
authors.affiliation: Department of Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada. Electronic address: togas.tulandi@mcgill.ca.
authors.forename: Togas
authors.initials: T
authors.lastname: Tulandi
authors.affiliation: Department of Pathology, McGill University, Montreal, Quebec, Canada.
authors.forename: Alex
authors.initials: A
authors.lastname: Ferenczy
mesh_terms: D000328:Adult; D001706:Biopsy; D005260:Female; D005629:Frozen Sections; D006801:Humans; D007430:Intraoperative Care; D010535:Laparoscopy / Q000379:methods; D007889:Leiomyoma / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D014594:Uterine Neoplasms / Q000473:pathology* / Q000601:surgery
keywords: Frozen section; Hysterectomy; Laparoscopy; Morcellation; Myoma; Myomectomy; Sarcoma; Tru-Cut needle biopsy