title: Sleep debt and obesity.
abstract: Short sleep duration has been shown to be associated with elevated body mass index (BMI) in many epidemiological studies. Several pathways could link sleep deprivation to weight gain and obesity, including increased food intake, decreased energy expenditure, and changes in levels of appetite-regulating hormones, such as leptin and ghrelin. A relatively new factor that is contributing to sleep deprivation is the use of multimedia (e.g. television viewing, computer, and internet), which may aggravate sedentary behavior and increase caloric intake. In addition, shift-work, long working hours, and increased time commuting to and from work have also been hypothesized to favor weight gain and obesity-related metabolic disorders, because of their strong link to shorter sleep times. This article reviews the epidemiological, biological, and behavioral evidence linking sleep debt and obesity.
authors.affiliation: Université Paris Descartes, Sorbonne Paris Cité, APHP, Hôtel Dieu, Centre du Sommeil et de la Vigilance de l'Hôtel Dieu de Paris, Equipe d'accueil VIFASOM EAU07 , Paris , France.
authors.forename: Virginie
authors.initials: V
authors.lastname: Bayon
authors.forename: Damien
authors.initials: D
authors.lastname: Leger
authors.forename: Danielle
authors.initials: D
authors.lastname: Gomez-Merino
authors.forename: Marie-Françoise
authors.initials: MF
authors.lastname: Vecchierini
authors.forename: Mounir
authors.initials: M
authors.lastname: Chennaoui
mesh_terms: D001066:Appetite / Q000502:physiology; D015992:Body Mass Index; D002149:Energy Intake / Q000502:physiology; D004734:Energy Metabolism / Q000502:physiology; D054439:Ghrelin / Q000378:metabolism; D006801:Humans; D020738:Leptin / Q000378:metabolism; D009765:Obesity / Q000453:epidemiology / Q000209:etiology*; D057185:Sedentary Behavior; D012890:Sleep / Q000502:physiology*; D012892:Sleep Deprivation / Q000150:complications*; D015430:Weight Gain / Q000502:physiology
chemical_list: D054439:Ghrelin; D020738:Leptin
keywords: Energy expenditure; energy intake; epidemiology; ghrelin; leptin; obesity; sleep; sleep deprivation