title: Probes for optical imaging: new developments.
abstract: Recent developments of fluorescent probes beyond approved indocyanine green (ICG) - itself increasingly spreading into new imaging applications like lymphatic mapping, arthritis imaging and tumor surgery - exploit various photophysical and biochemical mechanisms to monitor molecular events with higher specificity and accuracy. Emphasizing nanoparticulate formulations, targeted conjugates, activatable probes, probes with a sensor function and multimodality probes, this review discusses advantages and limitations of each type of probe, thereby critically assessing the desired translation into the clinic.:
authors.affiliation: mivenion GmbH, Robert-Koch-Platz 4, D-10115 Berlin, Germany. Electronic address:licha@mivenion.com.
authors.forename: Kai
authors.initials: K
authors.lastname: Licha
authors.affiliation: BAM Bundesanstalt für Materialforschung, Richard-Willstaetter-Str. 11, D-12489 Berlin, Germany. Electronic address:ute.resch@bam.de.
authors.forename: Ute
authors.initials: U
authors.lastname: Resch-Genger