title: The interrelated effects of 2D angiographic morphological variables and aneurysm rupture.
abstract: OBJECTIVE
  To investigate the correlations between morphological parameters and rupture status in cerebral aneurysm patients.
  
  
  METHODS
  We conducted a retrospective study of 34 patient records from March 2010 to December 2012. The morphological parameters of 34 ruptured and 42 unruptured cerebral aneurysms in 34 patients (males: female, 15:19; mean age 55.79+/-10.64 years) leading to subarachnoid hemorrhage were examined using 3D (dimension) digital subtraction angiography (DSA) models, to identify the correlation between 2D morphological parameters and risk factors of rupture status with univariate and multivariate analysis.
  
  
  RESULTS
  The 2D morphological parameters in ruptured aneurysms were significantly different from those observed in unruptured aneurysms (p<0.05), though only size and height-width ratios independently predicted rupture status. Dmax, Hmax, bottleneck factor, and size ratio significantly correlated with height-width ratio in ruptured but not unruptured aneurysms.
  
  
  CONCLUSIONS
  A specific set of morphological characteristics, most notably size and height-width ratios, may help to understand rupture risk by indicating arterial stretch character in cerebral aneurysms patients.
authors.affiliation: Department of Neurosurgery, Shaoxing City People`s Hospital, Shaoxing 312000, Zhejiang Province, China. Tel. +86 13676884796. Fax. +86 (21) 64085875. E-mail: sxrqtl@163.com.
authors.forename: Tianlun
authors.initials: T
authors.lastname: Qiu
authors.forename: Guoliang
authors.initials: G
authors.lastname: Jin
authors.forename: Wuqiao
authors.initials: W
authors.lastname: Bao
mesh_terms: D000328:Adult; D000368:Aged; D017542:Aneurysm, Ruptured / Q000000981:diagnostic imaging*; D015901:Angiography, Digital Subtraction / Q000379:methods*; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012307:Risk Factors; D013345:Subarachnoid Hemorrhage / Q000000981:diagnostic imaging*