title: A sensitive SERS assay for detecting proteins and nucleic acids using a triple-helix molecular switch for cascade signal amplification.
abstract: A novel surface-enhanced Raman scattering (SERS) detection system is developed for proteins and nucleic acids based on a triple-helix molecular switch for multiple cycle signal amplification, achieving high sensitivity, universality, rapid analysis, and high selectivity.
authors.affiliation: College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, P. R. China. tangb@sdnu.edu.cn.
authors.forename: Sujuan
authors.initials: S
authors.lastname: Ye
authors.forename: Yanying
authors.initials: Y
authors.lastname: Wu
authors.forename: Wen
authors.initials: W
authors.lastname: Zhang
authors.forename: Na
authors.initials: N
authors.lastname: Li
authors.forename: Bo
authors.initials: B
authors.lastname: Tang
mesh_terms: D009696:Nucleic Acids / Q000032:analysis*; D011506:Proteins / Q000032:analysis*; D013059:Spectrum Analysis, Raman / Q000379:methods*
chemical_list: D009696:Nucleic Acids; D011506:Proteins