title: [Monitoring of liver function in the critically ill].
abstract: Liver failure and hepatic dysfunction represent diagnostic and therapeutic challenges for the intensivist. Besides acute liver failure, hypoxic hepatitis, sepsis and (secondary) sclerosing cholangitis may lead to massive liver dysfunction with subsequent multiorgan dysfunction syndrome that limits survival. Among classical laboratory parameters (so-called static liver parameters) liver function tests may help with the diagnosis to allow early treatment or prevention of liver dysfunction. The aim of this article is to present the current aspects of liver function monitoring and to provide guidelines to the intensivist for diagnosing liver dysfunction in the intensive care setting.
authors.affiliation: Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Jena, Erlanger Allee 101, 07747, Jena, Deutschland, christoph.sponholz@med.uni-jena.de.
authors.forename: C
authors.initials: C
authors.lastname: Sponholz
authors.forename: F A
authors.initials: FA
authors.lastname: Gonnert
authors.forename: A
authors.initials: A
authors.lastname: Kortgen
authors.forename: M
authors.initials: M
authors.lastname: Bauer
mesh_terms: D003422:Critical Care / Q000379:methods*; D016638:Critical Illness; D006801:Humans; D008099:Liver / Q000503:physiopathology*; D008107:Liver Diseases / Q000503:physiopathology*; D008111:Liver Function Tests; D008991:Monitoring, Physiologic / Q000379:methods*