title: Detection of colistin sensitivity in clinical isolates of Acinetobacter baumannii in Iran.
abstract: BACKGROUND
  Nosocomial infection caused by Acinetobacter baumannii has emerged as a serious problem world-wide. Finding the suitable drug is an important priority. The aim of this study was to determine colistin (polymyxin E) resistance in clinical isolates of A. baumannii from intensive care units (ICUs) of Al Zahra Hospital.
  
  
  METHODS
  Sixty isolates of A. baumannii from patients hospitalized in ICU (Al Zahra Hospital, Isfahan University of Medical Sciences [IUMS]) were studied. All isolates of A. baumannii were tested for colistin susceptibility by Eopsilometer test (E-test).
  
  
  RESULTS
  Of the 60 isolates 57, (95%) were multidrug resistant (MDR) and 76.6% (46/60) were highly resistant. The rate of colistin resistant with the E-test method was 11.6% (7/60).
  
  
  CONCLUSIONS
  As the frequency of resistance to colistin is low, it can be used as an easily available drug for treatment of MDR A. baumannii strains, which are susceptible to colistin.
authors.affiliation: Department of Microbiology, Science and Research Branch, Islami Azad University, Kerman, Iran.
authors.forename: Bahareh
authors.initials: B
authors.lastname: Vakili
authors.affiliation: Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Hossein
authors.initials: H
authors.lastname: Fazeli
authors.affiliation: Nosocomial Infection Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Parisa
authors.initials: P
authors.lastname: Shoaei
authors.affiliation: Acquired Immunodeficiency Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Majid
authors.initials: M
authors.lastname: Yaran
authors.affiliation: Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Behrooz
authors.initials: B
authors.lastname: Ataei
authors.affiliation: Nosocomial Infection Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Farzin
authors.initials: F
authors.lastname: Khorvash
authors.affiliation: Department of Biology, Faculty of Science, Shahid Bahonar University of Kerman, Iran.
authors.forename: Moj
authors.initials: M
authors.lastname: Khaleghi
keywords: Acinetobacter baumannii; colistin resistance; multidrug resistant organism