title: Biocompatibility of a new pulp capping cement.
abstract: OBJECTIVE
  THE AIM OF THE PRESENT STUDY WAS TO EVALUATE THE BIOCOMPATIBILITY OF A NEW PULP CAPPING MATERIAL (BIODENTINE, SEPTODONT) COMPARED WITH REFERENCE PULP CAPPING MATERIALS: Dycal (Dentsply), ProRoot MTA (Dentsply) and MTA-Angelus (Angelus) by using murine odontoblast cell line and Alamar blue and MTT cytotoxicity tests.
  
  
  METHODS
  The citocompatibility of murine odontoblasts cells (MDPC-23) were evaluated at different times using a 24 Transwell culture plate by Alamar blue test and MTT assay.
  
  
  RESULTS
  The results were significantly different among the pulp capping materials tested. Biocompatibility was significant different among materials with different composition.
  
  
  CONCLUSIONS
  Biodentine and MTA-based products show lower cytotoxicity varying from calcium hydroxide-based material which present higher citotoxicity.
authors.affiliation: Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, Section of Dentistry, University of Pavia, Italy.
authors.forename: Claudio
authors.initials: C
authors.lastname: Poggio
authors.affiliation: Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, Section of Dentistry, University of Pavia, Italy.
authors.forename: Matteo
authors.initials: M
authors.lastname: Ceci
authors.affiliation: Department of Brain and Behavioural Sciences, University of Pavia, Italy.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Beltrami
authors.affiliation: Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, Section of Dentistry, University of Pavia, Italy.
authors.forename: Alberto
authors.initials: A
authors.lastname: Dagna
authors.affiliation: Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, Section of Dentistry, University of Pavia, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Colombo
authors.affiliation: Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, Section of Dentistry, University of Pavia, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Chiesa
keywords: MTT test; biocompatibility; murine odontoblast; pulp capping materials