title: Rejuvenation: it's in our blood.
abstract: It has been known for some time that blood from young mice can positively impact aged animals, while blood from old mice has the opposite effect. Recent studies report that rejuvenating effects of young blood extend to multiple tissues and have identified GDF11 and CCL11 as factors mediating these effects.
authors.affiliation: Department of Pathology, University of Washington, Seattle, WA 98195-7470, USA.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Bitto
authors.affiliation: Department of Pathology, University of Washington, Seattle, WA 98195-7470, USA. Electronic address: kaeber@uw.edu.
authors.forename: Matt
authors.initials: M
authors.lastname: Kaeberlein
mesh_terms: D000375:Aging; D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000378:metabolism; D054413:Chemokine CCL11 / Q000378:metabolism; D055412:Growth Differentiation Factors / Q000378:metabolism; D051379:Mice; D010227:Parabiosis
chemical_list: D019485:Bone Morphogenetic Proteins; C515457:Ccl11 protein, mouse; D054413:Chemokine CCL11; C119153:Gdf11 protein, mouse; D055412:Growth Differentiation Factors