title: Multiple pulmonary nodules and unexplained fever: when the pulmonologist fails.
abstract: We describe herein a difficult case of persistent and refractory fever, associated with multiple lung nodules, progressive respiratory failure and general deterioration. Our patient was carefully investigated for the possible causes of his symptoms, using current and advanced diagnostic procedures, either serological or by imaging. The confirmatory diagnosis of anaplastic T-cell lymphoma, was obtained only after an invasive procedure (with severe pneumothorax), although it was too late. This suggests that also very rare diseases should be considered in the presence of unexplained signs/symptoms, and that in such cases, aggressive diagnostic procedures should be applied as early as possible.
authors.affiliation: Respiratory Diseases, IRCCS S.Martino Hospital-IST, University of Genoa, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Mincarini
authors.affiliation: Respiratory Diseases, IRCCS S.Martino Hospital-IST, University of Genoa, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Bagnasco
authors.affiliation: Respiratory Diseases, IRCCS S.Martino Hospital-IST, University of Genoa, Italy.
authors.forename: M G
authors.initials: MG
authors.lastname: Ferrantino
authors.affiliation: Respiratory Diseases, IRCCS S.Martino Hospital-IST, University of Genoa, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Balbi
authors.affiliation: Respiratory Diseases, IRCCS S.Martino Hospital-IST, University of Genoa, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Passalacqua
mesh_terms: D017809:Fatal Outcome; D005334:Fever / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000175:diagnosis; D017728:Lymphoma, Large-Cell, Anaplastic / Q000150:complications* / Q000175:diagnosis; D016399:Lymphoma, T-Cell / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D055613:Multiple Pulmonary Nodules / Q000150:complications* / Q000175:diagnosis; D011237:Predictive Value of Tests; D015272:Pulmonary Medicine; D014057:Tomography, X-Ray Computed