title: Intense 18F-choline uptake after minor head injury: misleading PET/CT result in a patient with biochemical relapse of prostate adenocarcinoma.
abstract: We report the results of whole body 18F-fluorocholine (FCH) PET/CT in a single patient with biochemical suspicion of prostate adenocarcinoma relapse and recent history of minor head injury. PET showed an intense area of increased FCH uptake in the right parietal bone, without any morphological abnormality on either CT or skull radiographs. Understanding the radiotracer's physiological biodistribution as well as the nonmalignant etiologies of FCH uptake are essential requirements for a correct diagnostic interpretation of FCH PET/CT in patients with biological recurrence of prostate cancer.
authors.affiliation: From the *Service de Biophysique et de Médecine Nucléaire, Hôpitaux Universitaires de Strasbourg, Strasbourg, France; †ICube, Université de Strasbourg/CNRS UMR 7357, Strasbourg, France; ‡Fédération de Médecine Translationnelle de Strasbourg (FMTS), Faculté de Médecine, Strasbourg, France; §Cabinet Radiologie Imagerie de Bischwiller, Bischwiller, France; and ¶Département de Radiothérapie, Centre Paul Strauss, Strasbourg, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Leyendecker
authors.forename: Alessio
authors.initials: A
authors.lastname: Imperiale
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Matern
authors.forename: Georges
authors.initials: G
authors.lastname: Noël
authors.forename: Izzie-Jacques
authors.initials: IJ
authors.lastname: Namer
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging*; D002794:Choline / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D003951:Diagnostic Errors; D006801:Humans; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D012886:Skull / Q000000981:diagnostic imaging* / Q000293:injuries; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; C516370:fluoromethylcholine; D002794:Choline