title: A new fluorescent probe for Al(3+) based on rhodamine 6G and its application to bioimaging.
abstract: A water-soluble rhodamine-based derivative (L) has been rationally designed for selective recognition of Al(3+) in aqueous medium with good sensitivity. The addition of Al(3+) to the aqueous solution of L induces a remarkable fluorescence enhancement along with obvious color change detected by the naked eye, due to the ring-opening mechanism of the rhodamine spirolactam, which has been proved by single crystal diffraction analyses directly. The recognizing behavior has been investigated both experimentally and computationally. Furthermore, the fluorescent probe can also be used as a bioimaging reagent for detection of Al(3+) in living cells.
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450001, P. R. China. zangsqzg@zzu.edu.cn.
authors.forename: Yan
authors.initials: Y
authors.lastname: Fu
authors.forename: Xiu-Juan
authors.initials: XJ
authors.lastname: Jiang
authors.forename: Yan-Yan
authors.initials: YY
authors.lastname: Zhu
authors.forename: Bing-Jiang
authors.initials: BJ
authors.lastname: Zhou
authors.forename: Shuang-Quan
authors.initials: SQ
authors.lastname: Zang
authors.forename: Ming-Sheng
authors.initials: MS
authors.lastname: Tang
authors.forename: Hong-Yan
authors.initials: HY
authors.lastname: Zhang
authors.forename: Thomas C W
authors.initials: TC
authors.lastname: Mak
mesh_terms: D000535:Aluminum / Q000032:analysis*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D057054:Molecular Imaging / Q000379:methods; D061848:Optical Imaging / Q000379:methods; D012235:Rhodamines / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D005456:Fluorescent Dyes; D012235:Rhodamines; C026188:rhodamine 6G; D000535:Aluminum