title: [Pineal anlage tumor in a 8-month-old boy. The first case reported in Spanish language].
abstract: BACKGROUND
  The pineal anlage tumor is a very infrequent malign neoplasm. Even though it has been documented in literature, it is not listed yet in the World Health Organization's last nervous system classification (2007). It is a primitive pineal tumor with neuroepithelial and ectomesenchyme differentiation. Due to its low frequency, the understanding of its biological behavior and a suitable treatment are incomplete. In a search performed in PubMed with the term pineal anlage tumor, only seven informed cases were identified between 1989 and 2011.
  
  
  METHODS
  An 8-month-old infant was brought to medical attention because he had a progressive enlargement of the cephalic perimeter, and convergent strabismus of two months of evolution. A pineal tumor was identified. The histology showed glial tissue, ganglia cells, pigmented neuroepithelium and striate muscle cells. A ventriculoperitoneal derivation was done to diminish hydrocephalic pressure and also to led the complete surgical resection. The patient was treated with two courses of chemotherapy with carboplatine, ifosfamide and mesna. One year after the treatment, the patient is asymptomatic.
  
  
  CONCLUSIONS
  This is the first case reported in Spanish language. Given that it is a really infrequent tumor, it could be misdiagnosed as teratome, melanotic or mesoblastic medulloblastoma, or a melanotic neuroectodermal tumor of childhood (melanotic prognoma).
authors.affiliation: Servicio de Patología, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Distrito Federal, México. alirove0101@gmail.com.
authors.forename: Alicia
authors.initials: A
authors.lastname: Rodríguez-Velasco
authors.forename: Alma Griselda
authors.initials: AG
authors.lastname: Ramírez-Reyes
mesh_terms: D001932:Brain Neoplasms / Q000473:pathology*; D006801:Humans; D007223:Infant; D007802:Language; D008297:Male; D010870:Pineal Gland; D010871:Pinealoma / Q000473:pathology*
keywords: Child; Neoplasms; Pineal gland