title: The relationship between psychological symptoms, lung function and quality of life in children and adolescents with non-cystic fibrosis bronchiectasis.
abstract: OBJECTIVE
  The aim of this study was to evaluate the relationship between psychological symptoms and quality of life (QOL) and clinical variables in a cohort of children and adolescents with non-cystic fibrosis (non-CF) bronchiectasis.
  
  
  METHODS
  Seventy-six patients (aged 8-17years) participated in this study. Questionnaires were used to evaluate the psychological status and QOL of the patients and healthy controls. The patient and control groups were divided into child and adolescent groups to exclude the effect of puberty on psychological status.
  
  
  RESULTS
  No significant difference was found between patient and control groups for mean depression and trait anxiety scores. Only the child-rated physical health QOL scores were significantly lower for patients than the controls. Also, excepting physical health scores in adolescent group, all of the parent-rated QOL scores were significantly lower in both group and total subjects. Regarding determinants of QOL, age of children and FEV1/FVC percent predicted had positive effects, while dyspnea severity and trait anxiety had negative effects, for the sample as a whole.
  
  
  CONCLUSIONS
  Non-CF bronchiectasis is associated with poorer QOL in childhood. The impact of the disease on QOL occurs through both clinical and psychological variables.
authors.affiliation: Department of Child and Adolescent Psychiatry, Bakirkoy Research and Training Hospital for Psychiatry, Neurology and Neurosurgery, Istanbul, Turkey. Electronic address: mkbahali@yahoo.com.
authors.forename: Kayhan
authors.initials: K
authors.lastname: Bahali
authors.affiliation: Department of Pediatric Pulmonology, Medical Faculty, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Ahmet Hakan
authors.initials: AH
authors.lastname: Gedik
authors.affiliation: Department of Child and Adolescent Psychiatry, Medical Faculty of Meram, Necmettin Erbakan University, Konya, Turkey.
authors.forename: Ayhan
authors.initials: A
authors.lastname: Bilgic
authors.affiliation: Department of Pediatric Pulmonology, Medical Faculty, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Erkan
authors.initials: E
authors.lastname: Cakir
authors.affiliation: Department of Pediatrics, Medical Faculty, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Feyza
authors.initials: F
authors.lastname: Ustabas Kahraman
authors.affiliation: Department of Pediatrics, Medical Faculty, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Nurcan
authors.initials: N
authors.lastname: Keskin Osmanoglu
authors.affiliation: Department of Pediatrics, Medical Faculty, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Selcuk
authors.initials: S
authors.lastname: Uzuner
authors.affiliation: Department of Child and Adolescent Psychiatry, Bakirkoy Research and Training Hospital for Psychiatry, Neurology and Neurosurgery, Istanbul, Turkey.
authors.forename: Ali Guven
authors.initials: AG
authors.lastname: Kilicoglu
mesh_terms: D000293:Adolescent; D001007:Anxiety / Q000523:psychology*; D001987:Bronchiectasis / Q000503:physiopathology / Q000523:psychology*; D002648:Child; D003371:Cough / Q000523:psychology; D003863:Depression / Q000523:psychology*; D004417:Dyspnea / Q000523:psychology; D005260:Female; D006469:Hemoptysis / Q000523:psychology; D006801:Humans; D008297:Male; D011788:Quality of Life / Q000523:psychology*; D012720:Severity of Illness Index
keywords: Anxiety; Bronchiectasis; Child; Depression; Quality of life