title: Relationship between immunosuppressive medications adherence and quality of life and some patient factors in renal transplant patients in Iran.
abstract: OBJECTIVE
  About organ transplant, immunosuppressive medications adherence is a critical issue, because non-adherence to these medications causes rejection, reduces quality of life and increases treatment cost and mortality rate. Among these, the quality of life is deemed very important to evaluate treatment result and also it can be useful for discovering non adherence. The aim this study was to assess the relationship between medication adherence and quality of life and some patient factors in renal transplant patients.
  
  
  METHODS
  The study was a descriptive-correlational design and was done on renal transplant patients over 18 who had undergone surgery for over 3 months, and were inclined to participate. Sample size was 230 people and sampling was convenience. Quality of life questionnaire in renal transplant patients and Immunosuppressant Therapy Adherence Scale were filled by patients and the data was analyzed by SPSS15 software.
  
  
  RESULTS
  It showed that the mean score of quality of life in renal transplant patients was 21.65±4.03 and 57.8% of them did not adhere to immunosuppressive medications. Results of correlation between scores of immunosuppressive medication adherence and Quality of life showed that there were significant correlation in 3 dimensions of 4: health performance (p ≤ 0.0001 & rETA=0.23), social-economic (p=0.001 &amp; rETA=0.15), psychological-spiritual (p=0.011 &amp; rETA=0.15), also logistic test showed significant relationship between immunosuppressive medication adherence and number of transplantation (?=1.04, p= 0.048).
  
  
  CONCLUSIONS
  According to the results, health care providers i.e. nurses must note to medication adherence as a health enhancement factor while treating and educating to these patients.
authors.forename: Maryam
authors.initials: M
authors.lastname: Shabany Hamedan
authors.affiliation: School of Nursing and Midwifery, Department of medical surgical nursing , Iran University of Medical Science, Tehran, Iran. mohammadaliha.j@iums.ac.ir.
authors.forename: Jaleh
authors.initials: J
authors.lastname: Mohamad Aliha
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004334:Drug Administration Schedule; D005252:Fees, Pharmaceutical; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D007492:Iran; D016030:Kidney Transplantation / Q000523:psychology*; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D008875:Middle Aged; D011788:Quality of Life; D012959:Socioeconomic Factors; D013997:Time Factors; D055815:Young Adult; D016903:Drug Monitoring
chemical_list: D007166:Immunosuppressive Agents