title: Iodotrifluoromethylation of alkenes and alkynes with sodium trifluoromethanesulfinate and iodine pentoxide.
abstract: A scalable, selective, and operationally easy iodotrifluoromethylation of a wide range of alkenes and alkynes by using two simple and safe solids, sodium trifluoromethanesulfinate and iodine pentoxide, in aqueous medium has been developed. Mechanistic studies confirm that free-radical processes are involved in this system since the key radical intermediates such as CF(3) and β-CF(3) alkyl radicals have been clearly detected by spin trapping and electron spin resonance.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou, Gansu 730000, China.
authors.forename: Zhaojia
authors.initials: Z
authors.lastname: Hang
authors.forename: Zejiang
authors.initials: Z
authors.lastname: Li
authors.forename: Zhong-Quan
authors.initials: ZQ
authors.lastname: Liu
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000480:Alkynes / Q000737:chemistry*; D004578:Electron Spin Resonance Spectroscopy; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry*; D017613:Iodine Compounds / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure; D010087:Oxides / Q000737:chemistry*
chemical_list: D000475:Alkenes; D000480:Alkynes; D006845:Hydrocarbons, Fluorinated; D017613:Iodine Compounds; D008698:Mesylates; D010087:Oxides; C000592252:sodium trifluoromethanesulfinate; C555514:iodine pentoxide