title: Maxillary anterior ridge augmentation with recombinant human bone morphogenetic protein 2.
abstract: No human studies exist on the use of recombinant human bone morphogenetic protein 2 (rhBMP-2) on an absorbable collagen sponge (ACS) as a sole graft material for lateral ridge augmentation in large ridge defect sites. This series evaluates the treatment outcome of maxillary anterior lateral ridge augmentation with rhBMP-2/ACS. Twenty patients were treated with rhBMP-2/ACS and fixation screws for space maintenance. Cone beam volumetric tomography measurements were used to determine gain in ridge width, and a bone core biopsy was obtained. The mean horizontal ridge gain was 1.2 mm across sites, and every site gained width.
authors.forename: Ryan K
authors.initials: RK
authors.lastname: Edmunds
authors.forename: Brian L
authors.initials: BL
authors.lastname: Mealey
authors.forename: Michael P
authors.initials: MP
authors.lastname: Mills
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Thoma
authors.forename: John
authors.initials: J
authors.lastname: Schoolfield
authors.forename: David L
authors.initials: DL
authors.lastname: Cochran
authors.forename: Jim
authors.initials: J
authors.lastname: Mellonig
mesh_terms: D000328:Adult; D000368:Aged; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D055396:Bone Morphogenetic Protein 2 / Q000008:administration & dosage*; D054893:Cone-Beam Computed Tomography; D006801:Humans; D008437:Maxilla / Q000601:surgery*; D008875:Middle Aged; D011994:Recombinant Proteins / Q000008:administration & dosage; D013524:Surgical Flaps
chemical_list: C525718:BMP2 protein, human; D055396:Bone Morphogenetic Protein 2; D011994:Recombinant Proteins