title: [Cannabis smoking and lung cancer].
abstract: Cannabis is the most commonly smoked illicit substance in the world. It can be smoked alone in plant form (marijuana) but it is mainly smoked mixed with tobacco. The combined smoking of cannabis and tobacco is a common-place phenomenon in our society. However, its use is responsible for severe pulmonary consequences. The specific impact of smoking cannabis is difficult to assess precisely and to distinguish from the effect of tobacco. Marijuana smoke contains polycyclic aromatic hydrocarbons and carcinogens at higher concentration than tobacco smoke. Cellular, tissue, animal and human studies, and also epidemiological studies, show that marijuana smoke is a risk factor for lung cancer. Cannabis exposure doubles the risk of developing lung cancer. This should encourage clinicians to identify cannabis use and to offer patients support in quitting.
authors.affiliation: Service de pneumologie, unité de tabacologie, CHU La Milétrie, pavillon René-Beauchant, BP 577, 86021 Poitiers, France. Electronic address: m.underner@chu-poitiers.fr.
authors.forename: M
authors.initials: M
authors.lastname: Underner
authors.affiliation: Service de pneumologie, CHU d'Angers, 49000 Angers, France.
authors.forename: T
authors.initials: T
authors.lastname: Urban
authors.affiliation: Dispensaire Emile-Roux, CLAT 63, 63000 Clermont-Ferrand, France.
authors.forename: J
authors.initials: J
authors.lastname: Perriot
authors.affiliation: Service de psychiatrie-addictologie, CHU de Clermont-Ferrand, 63000 Clermont-Ferrand, France.
authors.forename: I
authors.initials: I
authors.lastname: de Chazeron
authors.affiliation: Service de pneumologie, unité de tabacologie, CHU La Milétrie, pavillon René-Beauchant, BP 577, 86021 Poitiers, France.
authors.forename: J-C
authors.initials: JC
authors.lastname: Meurice
mesh_terms: D000818:Animals; D002283:Carcinoma, Bronchogenic / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology / Q000209:etiology*; D008385:Marijuana Smoking / Q000009:adverse effects* / Q000453:epidemiology; D012307:Risk Factors; D012906:Smoke / Q000009:adverse effects; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology; D014026:Nicotiana
chemical_list: D012906:Smoke
keywords: Cancer bronchique; Cannabinoïdes; Cannabis; Lung cancer; Marijuana; Tetrahydrocannabinol; Tétrahydrocannabinol