title: Obsessive Compulsive Treatment Efficacy Trial (OCTET) comparing the clinical and cost effectiveness of self-managed therapies: study protocol for a randomised controlled trial.
abstract: BACKGROUND
  UK National Institute of Health and Clinical Excellence guidelines for obsessive compulsive disorder (OCD) specify recommendations for the treatment and management of OCD using a stepped care approach. Steps three to six of this model recommend treatment options for people with OCD that range from low-intensity guided self-help (GSH) to more intensive psychological and pharmacological interventions. Cognitive behavioural therapy (CBT), including exposure and response prevention, is the recommended psychological treatment. However, whilst there is some preliminary evidence that self-managed therapy packages for OCD can be effective, a more robust evidence base of their clinical and cost effectiveness and acceptability is required.
  
  
  METHODS
  Our proposed study will test two different self-help treatments for OCD: 1) computerised CBT (cCBT) using OCFighter, an internet-delivered OCD treatment package; and 2) GSH using a book. Both treatments will be accompanied by email or telephone support from a mental health professional. We will evaluate the effectiveness, cost and patient and health professional acceptability of the treatments.
  
  
  CONCLUSIONS
  This study will provide more robust evidence of efficacy, cost effectiveness and acceptability of self-help treatments for OCD. If cCBT and/or GSH prove effective, it will provide additional, more accessible treatment options for people with OCD.
  
  
  BACKGROUND
  Current Controlled Trials: ISRCTN73535163. Date of registration: 5 April 2011.
authors.affiliation: School of Nursing, Midwifery & Social Work, The University of Manchester, Manchester, UK. judith.l.gellatly@manchester.ac.uk.
authors.forename: Judith
authors.initials: J
authors.lastname: Gellatly
authors.forename: Peter
authors.initials: P
authors.lastname: Bower
authors.forename: Dean
authors.initials: D
authors.lastname: McMillan
authors.forename: Christopher
authors.initials: C
authors.lastname: Roberts
authors.forename: Sarah
authors.initials: S
authors.lastname: Byford
authors.forename: Penny
authors.initials: P
authors.lastname: Bee
authors.forename: Simon
authors.initials: S
authors.lastname: Gilbody
authors.forename: Catherine
authors.initials: C
authors.lastname: Arundel
authors.forename: Gillian
authors.initials: G
authors.lastname: Hardy
authors.forename: Michael
authors.initials: M
authors.lastname: Barkham
authors.forename: Shirley
authors.initials: S
authors.lastname: Reynolds
authors.forename: Lina
authors.initials: L
authors.lastname: Gega
authors.forename: Patricia
authors.initials: P
authors.lastname: Mottram
authors.forename: Nicola
authors.initials: N
authors.lastname: Lidbetter
authors.forename: Rebecca
authors.initials: R
authors.lastname: Pedley
authors.forename: Emily
authors.initials: E
authors.lastname: Peckham
authors.forename: Janice
authors.initials: J
authors.lastname: Connell
authors.forename: Jo
authors.initials: J
authors.lastname: Molle
authors.forename: Neil
authors.initials: N
authors.lastname: O'Leary
authors.forename: Karina
authors.initials: K
authors.lastname: Lovell
mesh_terms: D001291:Attitude of Health Personnel; D001877:Books; D002985:Clinical Protocols; D015928:Cognitive Behavioral Therapy / Q000191:economics*; D003362:Cost-Benefit Analysis; D017048:Health Care Costs; D006297:Health Services Accessibility / Q000191:economics; D006801:Humans; D020407:Internet / Q000191:economics; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000191:economics / Q000503:physiopathology / Q000628:therapy*; D010342:Patient Acceptance of Health Care; D011237:Predictive Value of Tests; D011569:Psychiatric Status Rating Scales; D012107:Research Design; D012648:Self Care / Q000191:economics*; D013813:Therapy, Computer-Assisted / Q000191:economics*; D013997:Time Factors; D016896:Treatment Outcome; D006113:United Kingdom