title: Diffuse Pulmonary Uptake of Tc-99m Methylene Diphosphonate in a Patient with Non-tuberculosis Mycobacterial Infection.
abstract: Extra-osseous uptake of bone-seeking radiopharmaceuticals has been reported at various sites and it is known to be induced by various causes. Diffuse pulmonary infection, such as tuberculosis, can be a cause of lung uptake of bone-scan agent. Here we report on a patient with non-tuberculosis mycobacterial infection (NTM) who demonstrated diffuse pulmonary uptake on Tc-99m MDP bone scan. After medical treatment for NTM, the patient's lung lesions improved. Extraskeletal lung Tc-99m MDP uptake on bone scan may suggest lung parenchymal damage associated with disease activity.
authors.affiliation: Department of Nuclear Medicine, Seoul National University College of Medicine, 28 Yeongeon-dong Jongno-gu, Seoul, Korea ; Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Hyun-Woo
authors.initials: HW
authors.lastname: Kwon
authors.affiliation: Department of Nuclear Medicine, Seoul National University College of Medicine, 28 Yeongeon-dong Jongno-gu, Seoul, Korea ; Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: June-Key
authors.initials: JK
authors.lastname: Chung
authors.affiliation: Department of Radiology, University Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
authors.forename: Aini
authors.initials: A
authors.lastname: Ab-Aziz
authors.affiliation: Department of Nuclear Medicine, Seoul National University College of Medicine, 28 Yeongeon-dong Jongno-gu, Seoul, Korea ; Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Dong Soo
authors.initials: DS
authors.lastname: Lee
keywords: Diffuse pulmonary uptake; Non-tuberculous mycobacterium; Tc-99m MDP