title: Incidence of deferasirox-associated renal tubular dysfunction in children and young adults with beta-thalassaemia.
authors.affiliation: Department of Paediatrics & Adolescent Medicine, Li Ka Shing Faculty of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.
authors.forename: Cathleen Michelle A
authors.initials: CM
authors.lastname: Dee
authors.forename: Daniel Ka Leung
authors.initials: DK
authors.lastname: Cheuk
authors.forename: Shau-Yin
authors.initials: SY
authors.lastname: Ha
authors.forename: Alan Kwok-Shing
authors.initials: AK
authors.lastname: Chiang
authors.forename: Godfrey Chi-Fung
authors.initials: GC
authors.lastname: Chan
mesh_terms: D000293:Adolescent; D000471:Alkalosis / Q000139:chemically induced; D001565:Benzoates / Q000009:adverse effects* / Q000627:therapeutic use; D015913:Chelation Therapy / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D000077588:Deferasirox; D000077543:Deferiprone; D003676:Deferoxamine / Q000627:therapeutic use; D005198:Fanconi Syndrome / Q000139:chemically induced; D005260:Female; D006801:Humans; D007502:Iron Chelating Agents / Q000009:adverse effects* / Q000627:therapeutic use; D007674:Kidney Diseases / Q000139:chemically induced*; D007684:Kidney Tubules / Q000187:drug effects / Q000503:physiopathology; D008297:Male; D011728:Pyridones / Q000627:therapeutic use; D012189:Retrospective Studies; D065227:Transfusion Reaction; D014230:Triazoles / Q000009:adverse effects* / Q000627:therapeutic use; D014883:Water-Electrolyte Imbalance / Q000139:chemically induced; D055815:Young Adult; D001613:beta 2-Microglobulin / Q000032:analysis; D017086:beta-Thalassemia / Q000150:complications* / Q000188:drug therapy / Q000628:therapy
chemical_list: D001565:Benzoates; D007502:Iron Chelating Agents; D011728:Pyridones; D014230:Triazoles; D001613:beta 2-Microglobulin; D000077543:Deferiprone; D003676:Deferoxamine; D000077588:Deferasirox
keywords: deferasirox; iron overload; renal tubular dysfunction; serum electrolyte; β-thalassaemia