title: Advances in the management of squamous cell carcinoma of the head and neck.
abstract: Squamous cell carcinoma of the head and neck (SCCHN) is the sixth most common cancer worldwide. The main risk factors for cancers of the oral cavity, larynx, oropharynx, and hypopharynx are alcohol and tobacco use. In addition, the human papillomavirus (HPV) is an established cause of oropharyngeal cancer. An experienced multidisciplinary team is necessary for adequate management and optimal outcome. The treatment of locally advanced disease generally requires various combinations of radiotherapy, surgery, and systemic therapy, but despite this aggressive multimodal treatment, 40% to 60% of the patients will relapse. In this report, we will discuss recent advances in the management of SCCHN, including new developments in molecular biology, imaging, and treatment.
authors.affiliation: Clinique de cancérologie cervico-maxillo-faciale, Centre du cancer et d'hématologie, Cliniques universitaires Saint-Luc and Institut de Recherche Clinique et Expérimentale (IREC), Université catholique de Louvain 10 Avenue Hippocrate, 1200 Brussels Belgium.
authors.forename: Jean-Pascal
authors.initials: JP
authors.lastname: Machiels
authors.affiliation: Clinique de cancérologie cervico-maxillo-faciale, Centre du cancer et d'hématologie, Cliniques universitaires Saint-Luc and Institut de Recherche Clinique et Expérimentale (IREC), Université catholique de Louvain 10 Avenue Hippocrate, 1200 Brussels Belgium.
authors.forename: Maarten
authors.initials: M
authors.lastname: Lambrecht
authors.affiliation: Clinique de cancérologie cervico-maxillo-faciale, Centre du cancer et d'hématologie, Cliniques universitaires Saint-Luc and Institut de Recherche Clinique et Expérimentale (IREC), Université catholique de Louvain 10 Avenue Hippocrate, 1200 Brussels Belgium.
authors.forename: François-Xavier
authors.initials: FX
authors.lastname: Hanin
authors.affiliation: Clinique de cancérologie cervico-maxillo-faciale, Centre du cancer et d'hématologie, Cliniques universitaires Saint-Luc and Institut de Recherche Clinique et Expérimentale (IREC), Université catholique de Louvain 10 Avenue Hippocrate, 1200 Brussels Belgium.
authors.forename: Thierry
authors.initials: T
authors.lastname: Duprez
authors.affiliation: Clinique de cancérologie cervico-maxillo-faciale, Centre du cancer et d'hématologie, Cliniques universitaires Saint-Luc and Institut de Recherche Clinique et Expérimentale (IREC), Université catholique de Louvain 10 Avenue Hippocrate, 1200 Brussels Belgium.
authors.forename: Vincent
authors.initials: V
authors.lastname: Gregoire
authors.affiliation: Clinique de cancérologie cervico-maxillo-faciale, Centre du cancer et d'hématologie, Cliniques universitaires Saint-Luc and Institut de Recherche Clinique et Expérimentale (IREC), Université catholique de Louvain 10 Avenue Hippocrate, 1200 Brussels Belgium.
authors.forename: Sandra
authors.initials: S
authors.lastname: Schmitz
authors.affiliation: Clinique de cancérologie cervico-maxillo-faciale, Centre du cancer et d'hématologie, Cliniques universitaires Saint-Luc and Institut de Recherche Clinique et Expérimentale (IREC), Université catholique de Louvain 10 Avenue Hippocrate, 1200 Brussels Belgium.
authors.forename: Marc
authors.initials: M
authors.lastname: Hamoir