title: Exercise programme in patients with cystic fibrosis: a randomized controlled trial.
abstract: OBJECTIVE
  Assess the effects of a home exercise programme, based on aerobic training and muscle strength training, in patients with cystic fibrosis (CF), for a period of 3 months.
  
  
  METHODS
  Randomised controlled clinical experiment, with an analysis of intention to treat including clinically stable patients with CF and of age ≥ 16. Assessments include: a 6 min walk test (6 MWT), one-repetition maximum strength test (1 RM), spirometry and quality of life questionnaires. The patients randomised for the exercise group exercise group followed a home exercise protocol, supervised by telephone, while the control group maintained their usual activities.
  
  
  RESULTS
  41 Patients were included, 22 in the control group and 19 in the exercise group. The exercise group presented a significant increase in muscle strength in upper limbs (UULL) on the 1 RM test. There was no significant difference between groups on the scores for general quality of life and specifically for CF and in the distance walked on the 6 MWT.
  
  
  CONCLUSIONS
  The study demonstrated that a home exercise programme had positive effects in adult patients with CF, including gain in muscle strength in UULL. No increase in tolerance to exercise was shown and improvement in the quality of life of the patients who received intervention.
authors.affiliation: Faculdade de Fisioterapia, Universidade Federal do Rio Grande do Sul (UFRGS), Brazil.
authors.forename: Paula Maria Eidt
authors.initials: PM
authors.lastname: Rovedder
authors.affiliation: UFRGS, Brazil.
authors.forename: Josani
authors.initials: J
authors.lastname: Flores
authors.affiliation: UFRGS, Brazil.
authors.forename: Bruna
authors.initials: B
authors.lastname: Ziegler
authors.affiliation: Faculdade de Medicina, UFRGS, Brazil.
authors.forename: Fernanda
authors.initials: F
authors.lastname: Casarotto
authors.affiliation: UFRGS, Brazil.
authors.forename: Patrícia
authors.initials: P
authors.lastname: Jaques
authors.affiliation: UFRGS, Brazil.
authors.forename: Sergio Saldanha Menna
authors.initials: SS
authors.lastname: Barreto
authors.affiliation: Serviço de Pneumologia, HCPA, Faculdade de Medicina, UFRGS, Brazil. Electronic address: paula.rovedder@metodistadosul.edu.br.
authors.forename: Paulo de Tarso Roth
authors.initials: Pde T
authors.lastname: Dalcin
mesh_terms: D003550:Cystic Fibrosis / Q000503:physiopathology / Q000628:therapy*; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D005541:Forced Expiratory Volume / Q000502:physiology; D006699:Home Care Services; D006801:Humans; D008297:Male; D053580:Muscle Strength / Q000502:physiology; D018482:Muscle, Skeletal / Q000502:physiology; D011446:Prospective Studies; D011788:Quality of Life; D014797:Vital Capacity / Q000502:physiology; D055815:Young Adult
keywords: Aerobic training; Cystic fibrosis; Home exercise programme; Muscle strength training