title: [Reasearch on evolution and transition of processing method of fuzi in ancient and modern times].
abstract: Fuzi is a medicine used for rescuing from collapse by restoring yang as well as a famous toxic traditional Chinese medicine. In order to ensure the efficacy and safe medication, Fuzi has mostly been applied after being processed. There have been different Fuzi processing methods recorded by doctors of previous generations. Besides, there have also been differences in Fuzi processing methods recorded in modern pharmacopeia and ancient medical books. In this study, the authors traced back to medical books between the Han Dynasty and the period of Republic of China, and summarized Fuzi processing methods collected in ancient and modern literatures. According to the results, Fuzi processing methods and using methods have changed along with the evolution of dynasties, with differences in ancient and modern processing methods. Before the Tang Dynasty, Fuzi had been mostly processed and soaked. From Tang to Ming Dynasties, Fuzi had been mostly processed, soaked and stir-fried. During the Qing Dynasty, Fuzi had been mostly soaked and boiled. In the modem times, Fuzi is mostly processed by being boiled and soaked. Before the Tang Dynasty, a whole piece of Fuzi herbs or their fragments had been applied in medicines; Whereas their fragments are primarily used in the modern times. Because different processing methods have great impacts on the toxicity of Fuzi, it is suggested to study Fuzi processing methods.
authors.forename: Chan-Chan
authors.initials: CC
authors.lastname: Liu
authors.forename: Ming-En
authors.initials: ME
authors.lastname: Cheng
authors.forename: Hai-Yan
authors.initials: HY
authors.lastname: Duan
authors.forename: Hua-Sheng
authors.initials: HS
authors.lastname: Peng
mesh_terms: D002626:Chemistry, Pharmaceutical / Q000266:history* / Q000379:methods*; D002681:China; D004224:Diterpenes; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D049668:History, 15th Century; D049669:History, 16th Century; D049670:History, 17th Century; D049671:History, 18th Century; D049672:History, 19th Century; D049690:History, Ancient; D049691:History, Medieval; D006801:Humans; D008516:Medicine, Chinese Traditional / Q000266:history / Q000379:methods; D010936:Plant Extracts / Q000737:chemistry*
chemical_list: D004224:Diterpenes; D004365:Drugs, Chinese Herbal; D010936:Plant Extracts; C575009:fuzi drug herbal