title: Effect of biometric characteristics on the change of biomechanical properties of the human cornea due to cataract surgery.
abstract: OBJECTIVE
  To determine the impact of biometric characteristics on changes of biomechanical properties of the human cornea due to standard cataract surgery using biomechanical analysis.
  
  
  METHODS
  This prospective consecutive cross-sectional study comprised 54 eyes with cataract in stages I or II that underwent phacoemulsification and IOL implantation. CH, CRF, IOPg, and IOPcc intraocular pressure were measured by biomechanical analysis preoperatively and at 1 month postoperatively. Changes (Δ) were calculated as preoperative value versus postoperative value. Biometrical data were extracted from TMS-5 (CSI and SAI), IOLMaster (AL), and EM-3000 (CCT and ECC) preoperatively.
  
  
  RESULTS
  The average values of the changes were ΔCH = -0.45 ± 1.27 mmHg, ΔCRF = -0.88 ± 1.1 mmHg, ΔIOPg = -1.58 ± 3.15 mmHg, and ΔIOPcc = -1.45 ± 3.93 mmHg. The higher the CSI the smaller the decrease in CH (r = 0.302, P = 0.028). The higher the CCT the larger the decrease in CRF (r = -0.371, P = 0.013). The higher the AL the smaller the decrease in IOPg (r = 0.417, P = 0.005). The higher the AL, SAI, and EEC the smaller the decrease in IOPcc (r = 0.351, P = 0.001; r = -0.478, P < 0.001; r = 0.339, P = 0.013).
  
  
  CONCLUSIONS
  Corneal biomechanical properties were affected by comprehensive factors after cataract surgery, including corneal endothelium properties, biometry, and geometrical characteristics.
authors.affiliation: Department of Ophthalmology, Saarland University Medical Center, Kirrberger Straße 100, 66424 Homburg/Saar, Germany.
authors.forename: Xuefei
authors.identifier: 0000-0003-4421-6017
authors.initials: X
authors.lastname: Song
authors.affiliation: Experimental Ophthalmology, Saarland University, Kirrberger Straße 100, 66424 Homburg/Saar, Germany.
authors.forename: Achim
authors.initials: A
authors.lastname: Langenbucher
authors.affiliation: Department of Ophthalmology, Saarland University Medical Center, Kirrberger Straße 100, 66424 Homburg/Saar, Germany.
authors.forename: Zisis
authors.initials: Z
authors.lastname: Gatzioufas
authors.affiliation: Department of Ophthalmology, Saarland University Medical Center, Kirrberger Straße 100, 66424 Homburg/Saar, Germany.
authors.forename: Berthold
authors.initials: B
authors.lastname: Seitz
authors.affiliation: Department of Ophthalmology, Saarland University Medical Center, Kirrberger Straße 100, 66424 Homburg/Saar, Germany.
authors.forename: Moatasem
authors.initials: M
authors.lastname: El-Husseiny
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001696:Biomechanical Phenomena; D001699:Biometry; D002386:Cataract / Q000473:pathology / Q000503:physiopathology; D002387:Cataract Extraction; D003315:Cornea / Q000473:pathology / Q000503:physiopathology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged