title: [Localized neuropathic pain--5% lidocaine medicated patch as a first-line treatment and as add-on therapy: literature review and personal experience].
abstract: Localized neuropathic pain (LNP) is a type of neuropathic pain characterized by consistent and circumscribed area(s) of maximum pain, which are associated with negative or positive sensory signs and/or spontaneous symptoms typical of neuropathic pain. This description outlines the clinical features of a group of pathologies, in which a LNP can be diagnosed and for whom topical targeted treatment with 5% Lidocaine medicated plaster can be suggested. Indeed both American as well as European guidelines already suggest 5% Lidocaine medicated plaster as a first line treatment in post herpetic neuralgia and in general in the treatment of conditions such as diabetic painful polyneuropathy and post surgical pain where a LNP can be ascertain. In a daily practice of a Pain Unit however the usual case mix encompasses also other causes of LNP, most of them with a scanty pain control in spite of a ongoing polytherapy. Aims of this paper were to focus on 5% Lidocaine medicated plaster as a first line treatment in LNP and to add new insight on its possible use as add-on therapy reporting our data on a consecutive series of 42 patients affected by LNP under unsatisfactory polytherapy in which 5% Lidocaine medicated plaster was able to achieve a satisfactory pain control.
authors.affiliation: Servizio Neurofisiopatologia Unità di Diagnosi e Riabilitazione del Dolore Istituto Scientifico di Montescano IRCCS Fondazione "S. Maugeri" 27040 ‑ Montescano (PV) - roberto.casale@fsm.it.
authors.forename: R
authors.initials: R
authors.lastname: Casale
authors.forename: E
authors.initials: E
authors.lastname: Polati
authors.forename: V
authors.initials: V
authors.lastname: Schweiger
authors.forename: F
authors.initials: F
authors.lastname: Coluzzi
authors.forename: A
authors.initials: A
authors.lastname: Bhaskar
authors.forename: M
authors.initials: M
authors.lastname: Consalvo
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D000779:Anesthetics, Local / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009437:Neuralgia / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D059408:Pain Management / Q000379:methods*; D010147:Pain Measurement; D057968:Transdermal Patch
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine