title: Gene deletion speeds mutation rate.
abstract: The APOBEC proteins fight off viruses by editing their genomes. A deletion that removes one of the proteins produces large numbers of mutations in the human genome, potentially leading to cancer.
mesh_terms: D003564:Cytidine Deaminase / Q000378:metabolism*; D017353:Gene Deletion; D006801:Humans; D005810:Multigene Family; D059645:Mutation Rate; D009369:Neoplasms / Q000235:genetics* / Q000378:metabolism
chemical_list: D003564:Cytidine Deaminase