title: Primary pleural hybrid cellular schwannoma/perineurioma: a case report.
abstract: Hybrid schwannoma/perineurioma is a recently characterized benign nerve sheath tumor, most commonly affecting the lower limb and limb girdle. Hybrid tumors located in the subcutis of the trunk have not previously been reported to affect the pleura. We describe a 52-year-old man with dyspnea and thoracic pain due to a large mass in the right pleura, histologically composed of densely packed, S-100-positive spindle cells, intermixed with cells containing slender nuclei positive for epithelial membrane antigen, Glut-1, and claudin-1. To our knowledge, this is the first report of hybrid schwannoma/perineurioma in the pleura.
authors.affiliation: Department of Surgical and Molecular Pathology, The American British Cowdray Medical Center, Mexico City, Mexico. Electronic address: drsoriac@abchospital.com.
authors.forename: Danny
authors.initials: D
authors.lastname: Soria-Céspedes
authors.affiliation: Department of Surgery, The American British Cowdray Medical Center, Mexico City, Mexico. Electronic address: dannysoria@hotmail.com.
authors.forename: Carlos
authors.initials: C
authors.lastname: Robles-Vidal
authors.affiliation: Department of Internal Medicine, The American British Cowdray Medical Center, Mexico City, Mexico. Electronic address: dannysoriaces@yahoo.com.
authors.forename: Arturo
authors.initials: A
authors.lastname: Gómez-González
authors.affiliation: Department of Surgical and Molecular Pathology, The American British Cowdray Medical Center, Mexico City, Mexico. Electronic address: rositadeolivo_patologia@hotmail.com.
authors.forename: Rosalinda
authors.initials: R
authors.lastname: Peñaloza-Ramírez
authors.affiliation: Department of Surgical and Molecular Pathology, The American British Cowdray Medical Center, Mexico City, Mexico; Department of Tissue and Cell Biology, Universidad Panamericana, Mexico City, Mexico. Electronic address: cortiz@abchospital.com.
authors.forename: Carlos
authors.initials: C
authors.lastname: Ortiz-Hidalgo
mesh_terms: D002637:Chest Pain / Q000209:etiology; D062445:Claudin-1 / Q000378:metabolism; D004417:Dyspnea / Q000209:etiology; D051272:Glucose Transporter Type 1 / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D018396:Mucin-1 / Q000378:metabolism; D009378:Neoplasms, Multiple Primary; D018317:Nerve Sheath Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D009442:Neurilemmoma / Q000150:complications / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D010997:Pleural Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D049268:Positron-Emission Tomography; D009418:S100 Proteins / Q000378:metabolism; D014057:Tomography, X-Ray Computed
chemical_list: C568108:CLDN1 protein, human; D062445:Claudin-1; D051272:Glucose Transporter Type 1; D018396:Mucin-1; D009418:S100 Proteins