title: Intrameningioma metastasis of breast carcinoma.
abstract: Tumor-to-tumor metastasis of breast carcinoma to meningioma is a rare phenomenon. It is likely underdiagnosed given the relatively high prevalence and comorbidity of these two primary tumor types, the lack of standardized methodologies for its diagnosis, and the tendency to obfuscate this lesion with simple meningioma or cerebral metastasis of breast carcinoma. Careful histopathologic study of the resected meningioma is the cornerstone of diagnosis of these lesions, although certain conventional radiological features along with specialized modalities may clue the diagnosis. Vigilance for this lesion is appropriate in selected patients with known breast cancer or meningioma, as the two are often coexistent in the same patient, permitting tumor-to-tumor metastasis. Detection of this rare disease process may alter the treatment plan and prognosis. Here, we report a case of breast carcinoma-to-meningioma metastasis in a patient who developed subacute neurological decline while undergoing long-term treatment of her primary, late-stage breast cancer.
authors.affiliation: Department of Neurological Surgery, Northwestern University , Chicago, IL, USA.
authors.forename: Eli T
authors.initials: ET
authors.lastname: Sayegh
authors.affiliation: College of Physicians and Surgeons, Columbia University , New York, NY, USA.
authors.forename: Grant A
authors.initials: GA
authors.lastname: Henderson
authors.affiliation: College of Physicians and Surgeons, Columbia University , New York, NY, USA.
authors.forename: Ezra A
authors.initials: EA
authors.lastname: Burch
authors.affiliation: Department of Pathology, University of California , San Francisco, CA, USA.
authors.forename: Gerald F
authors.initials: GF
authors.lastname: Reis
authors.affiliation: Department of Radiology, University of California , San Francisco, CA, USA.
authors.forename: Soonmee
authors.initials: S
authors.lastname: Cha
authors.affiliation: Department of Neurological Surgery, Northwestern University , Chicago, IL, USA.
authors.forename: Taemin
authors.initials: T
authors.lastname: Oh
authors.affiliation: Department of Neurological Surgery, Northwestern University , Chicago, IL, USA.
authors.forename: Orin
authors.initials: O
authors.lastname: Bloch
authors.affiliation: Department of Neurological Surgery, Northwestern University , Chicago, IL, USA.
authors.forename: Andrew T
authors.initials: AT
authors.lastname: Parsa
keywords: adenocarcinoma; breast carcinoma; meningioma; metastasis; tumor-to-tumor