title: Demand-based web surveillance of sexually transmitted infections in Russia.
abstract: OBJECTIVE
  To investigate the possibility of using HIV- and syphilis-related web queries to predict incident diagnosis rates of sexually transmitted infections in Russia.
  
  
  METHODS
  The regional volume of HIV/syphilis queries, normalized to the total number of queries submitted to the most popular search engine, was used to predict the notification rates of HIV/syphilis in each region by applying both global non-spatial and spatial statistics.
  
  
  RESULTS
  Nationwide, both search volumes and regional HIV/syphilis diagnosis rates were positively spatially auto-correlated, indicating a clustered pattern of spatial distribution. A high positive correlation between notification rates and search volume was observed. Compared with linear models, spatially explicit geographically weighted models adjusted for broadband Internet diffusion proved superior in predicting the regional level of the HIV/syphilis epidemic on the basis of their search volume.
  
  
  CONCLUSIONS
  Timeliness, easy availability, low cost, and transparency make HIV- and syphilis-related web queries a promising addition to traditional methods of disease surveillance in Russia. Geographically weighted regression provides useful insights, as it is able to capture the spatial heterogeneity of the relationship between search volume and disease incidence.
authors.affiliation: Department of Health Sciences, University of Genoa, Genoa, Italy, alexander.domnich@gmail.com.
authors.forename: Alexander
authors.initials: A
authors.lastname: Domnich
authors.forename: Eva K
authors.initials: EK
authors.lastname: Arbuzova
authors.forename: Alessio
authors.initials: A
authors.lastname: Signori
authors.forename: Daniela
authors.initials: D
authors.lastname: Amicizia
authors.forename: Donatella
authors.initials: D
authors.lastname: Panatto
authors.forename: Roberto
authors.initials: R
authors.lastname: Gasparini
mesh_terms: D000293:Adolescent; D000328:Adult; D003625:Data Collection / Q000379:methods; D062665:Epidemiological Monitoring; D005260:Female; D005544:Forecasting; D006801:Humans; D015994:Incidence; D020407:Internet; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance / Q000379:methods*; D015995:Prevalence; D012426:Russia / Q000453:epidemiology; D012749:Sexually Transmitted Diseases / Q000175:diagnosis* / Q000453:epidemiology*; D055815:Young Adult