title: Decolonization to prevent Staphylococcus aureus transmission and infections in the neonatal intensive care unit.
abstract: Staphylococcus aureus (S. aureus) continues to be a leading cause of outbreaks and health-care-associated infections in neonatal intensive care units. In the first few months of life, many neonates acquire S. aureus as part of their delicate and evolving microbiota. Neonates that asymptomatically acquire S. aureus colonization are at increased risk of developing a subsequent S. aureus infection. This review discusses the epidemiology and prevention of S. aureus disease in neonates and how decolonization to eradicate S. aureus may decrease S. aureus transmission and infections in the neonatal intensive care unit.
authors.affiliation: Department of Pediatrics and Epidemiology, Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: V O
authors.initials: VO
authors.lastname: Popoola
authors.affiliation: 1] Department of Pediatrics and Epidemiology, Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA [2] Department of Hospital Epidemiology and Infection Control, Johns Hopkins Hospital, Baltimore, MD, USA.
authors.forename: A M
authors.initials: AM
authors.lastname: Milstone
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D058070:Asymptomatic Diseases; D002353:Carrier State; D003428:Cross Infection / Q000635:transmission*; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D016712:Mupirocin / Q000627:therapeutic use; D018570:Risk Assessment; D013203:Staphylococcal Infections / Q000635:transmission*
chemical_list: D000900:Anti-Bacterial Agents; D016712:Mupirocin