title: Mitochondrial priming of chronic lymphocytic leukemia patients associates Bcl-xL dependence with alvocidib response.
authors.affiliation: Eutropics Inc., Cambridge, MA, USA.
authors.forename: W E
authors.initials: WE
authors.lastname: Pierceall
authors.affiliation: Tolero Pharmaceuticals, Inc., Lehi, UT, USA.
authors.forename: S L
authors.initials: SL
authors.lastname: Warner
authors.affiliation: Eutropics Inc., Cambridge, MA, USA.
authors.forename: R J
authors.initials: RJ
authors.lastname: Lena
authors.affiliation: Eutropics Inc., Cambridge, MA, USA.
authors.forename: C
authors.initials: C
authors.lastname: Doykan
authors.affiliation: Eutropics Inc., Cambridge, MA, USA.
authors.forename: N
authors.initials: N
authors.lastname: Blake
authors.affiliation: Eutropics Inc., Cambridge, MA, USA.
authors.forename: M
authors.initials: M
authors.lastname: Elashoff
authors.affiliation: 1] Tolero Pharmaceuticals, Inc., Lehi, UT, USA [2] Translational Genomics Research Institute, Scottsdale, AZ, USA.
authors.forename: D V
authors.initials: DV
authors.lastname: Hoff
authors.affiliation: Tolero Pharmaceuticals, Inc., Lehi, UT, USA.
authors.forename: D J
authors.initials: DJ
authors.lastname: Bearss
authors.affiliation: Eutropics Inc., Cambridge, MA, USA.
authors.forename: M H
authors.initials: MH
authors.lastname: Cardone
authors.affiliation: Department of Internal Medicine, Division of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
authors.forename: L
authors.initials: L
authors.lastname: Andritsos
authors.affiliation: Department of Internal Medicine, Division of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Byrd
authors.affiliation: Department of Medicine, Duke Cancer Institute, Durham, NC, USA.
authors.forename: M C
authors.initials: MC
authors.lastname: Lanasa
authors.affiliation: Department of Internal Medicine, Division of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
authors.forename: M R
authors.initials: MR
authors.lastname: Grever
authors.affiliation: Department of Internal Medicine, Division of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
authors.forename: A J
authors.initials: AJ
authors.lastname: Johnson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000627:therapeutic use; D019008:Drug Resistance, Neoplasm / Q000235:genetics; D005260:Female; D005419:Flavonoids / Q000627:therapeutic use*; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy* / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D008928:Mitochondria / Q000502:physiology*; D010880:Piperidines / Q000627:therapeutic use*; D051020:bcl-X Protein / Q000235:genetics*
chemical_list: D000970:Antineoplastic Agents; C494811:BCL2L1 protein, human; D005419:Flavonoids; D010880:Piperidines; D051020:bcl-X Protein; C077990:alvocidib