title: Clean and fast cross-coupling of aryl halides in one-pot.
abstract: Unsymmetrically coupled biaryls are synthesized in high yield starting from different aryl bromides and bis(pinacolato)diboron by carrying out the Miyaura borylation reaction followed by the Suzuki-Miyaura reaction in the same reaction pot over 1-2 mol % SiliaCat DPP-Pd. The SiliaCat DPP-Pd catalyst is air-stable and the method does not require the use of inert conditions. The use of non-toxic isopropanol or 2-butanol as reaction solvent further adds to the environmental benefits of this new green synthetic methodology.
authors.affiliation: SiliCycle Inc., 2500, Parc-Technologique Blvd, Quebec City, Quebec, Canada G1P 4S6.
authors.forename: Valerica
authors.initials: V
authors.lastname: Pandarus
authors.affiliation: SiliCycle Inc., 2500, Parc-Technologique Blvd, Quebec City, Quebec, Canada G1P 4S6.
authors.forename: Geneviève
authors.initials: G
authors.lastname: Gingras
authors.affiliation: SiliCycle Inc., 2500, Parc-Technologique Blvd, Quebec City, Quebec, Canada G1P 4S6.
authors.forename: François
authors.initials: F
authors.lastname: Béland
authors.affiliation: Istituto per lo Studio dei Materiali Nanostrutturati, CNR, via U. La Malfa 153, 90146 Palermo, Italy.
authors.forename: Rosaria
authors.initials: R
authors.lastname: Ciriminna
authors.affiliation: Istituto per lo Studio dei Materiali Nanostrutturati, CNR, via U. La Malfa 153, 90146 Palermo, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Pagliaro
keywords: SiliaCat; Suzuki–Miyaura; borylation; cross-coupling; one-pot