title: Abdominal lymphangiomatosis in a 38-year-old female: case report and literature review.
abstract: Lymphangioma is an uncommon benign tumor that develops in the lymphatic system. Abdominal lymphangiomatosis is extremely rare in adult patients, and the clinical symptoms of this condition are complicated and atypical. We report a case of abdominal lymphangiomatosis in a 38-year-old female who presented with intestinal bleeding and protein-losing enteropathy, as well as lesions in the lung and bones. A computed tomography scan revealed multiple small cystic lesions without enhancement. Histological examination revealed microscopic cysts were submucosal, with walls composed of thin fibrous tissue, and D2-40 stained highlight the lining of the lymphatic channels by immunohistochemical method. We make a comparison with the cases reported before, and also discuss the diagnose of diffuse pulmonary lymphangiomatosis and Gorham's disease.
authors.affiliation: Ruo-Yang Lin, Tan-Zhou Chen, Wei Wu, Jian-Hong Wang, Qing-Xi Han, Department of Gastroenterology and Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China.
authors.forename: Ruo-Yang
authors.initials: RY
authors.lastname: Lin
authors.affiliation: Ruo-Yang Lin, Tan-Zhou Chen, Wei Wu, Jian-Hong Wang, Qing-Xi Han, Department of Gastroenterology and Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China.
authors.forename: Hai
authors.initials: H
authors.lastname: Zou
authors.affiliation: Ruo-Yang Lin, Tan-Zhou Chen, Wei Wu, Jian-Hong Wang, Qing-Xi Han, Department of Gastroenterology and Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China.
authors.forename: Tan-Zhou
authors.initials: TZ
authors.lastname: Chen
authors.affiliation: Ruo-Yang Lin, Tan-Zhou Chen, Wei Wu, Jian-Hong Wang, Qing-Xi Han, Department of Gastroenterology and Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Wu
authors.affiliation: Ruo-Yang Lin, Tan-Zhou Chen, Wei Wu, Jian-Hong Wang, Qing-Xi Han, Department of Gastroenterology and Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China.
authors.forename: Jian-Hong
authors.initials: JH
authors.lastname: Wang
authors.affiliation: Ruo-Yang Lin, Tan-Zhou Chen, Wei Wu, Jian-Hong Wang, Qing-Xi Han, Department of Gastroenterology and Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China.
authors.forename: Xiao-Lei
authors.initials: XL
authors.lastname: Chen
authors.affiliation: Ruo-Yang Lin, Tan-Zhou Chen, Wei Wu, Jian-Hong Wang, Qing-Xi Han, Department of Gastroenterology and Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China.
authors.forename: Qing-Xi
authors.initials: QX
authors.lastname: Han
mesh_terms: D000008:Abdominal Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D000328:Adult; D001706:Biopsy; D016099:Endoscopy, Gastrointestinal; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D007150:Immunohistochemistry; D008171:Lung Diseases / Q000151:congenital / Q000175:diagnosis / Q000209:etiology; D008200:Lymphangiectasis / Q000151:congenital / Q000175:diagnosis / Q000209:etiology; D008202:Lymphangioma / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D010015:Osteolysis, Essential / Q000175:diagnosis / Q000209:etiology; D011504:Protein-Losing Enteropathies / Q000175:diagnosis / Q000209:etiology; D014057:Tomography, X-Ray Computed
keywords: Abdominal lymphangiomatosis; Diffuse pulmonary lymphangiomatosis; Gastrointestinal bleeding; Gorham’s disease; Lymphangioma