title: Psychotic episode secondary to gonadotrophins.
abstract: OBJECTIVE
  To report a case of a substance-induced psychotic disorder secondary to ovulation induction therapy with gonadotrophins.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  We report a case of a psychotic episode secondary to gonadotrophins therapy. The acute episode was treated with antipsychotic (Aripiprazole). After 2 years the patient remains free of psychotic symptoms.
  
  
  CONCLUSIONS
  There have been several reports correlating low levels of estrogen with psychotic symptoms, leading to studies evaluating the possible effect of this hormone as an antipsychotic. In this case, we report psychotic symptoms with high levels of estradiol, which is contrary to that theory.
authors.affiliation: Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal. Electronic address: jdmrodrigues@gmail.com.
authors.forename: José Daniel Machado
authors.initials: JD
authors.lastname: Rodrigues
authors.affiliation: Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal.
authors.forename: Maria Georgina Santos
authors.initials: MG
authors.lastname: Lapa
authors.affiliation: University of Birmingham, United Kingdom.
authors.forename: Ian Fraser
authors.initials: IF
authors.lastname: Brockington
mesh_terms: D000328:Adult; D005260:Female; D005300:Fertility Agents, Female / Q000009:adverse effects*; D043373:Follicle Stimulating Hormone, Human / Q000009:adverse effects*; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy*; D008596:Menotropins / Q000009:adverse effects*; D011605:Psychoses, Substance-Induced / Q000209:etiology*; D011994:Recombinant Proteins / Q000009:adverse effects
chemical_list: D005300:Fertility Agents, Female; D043373:Follicle Stimulating Hormone, Human; D011994:Recombinant Proteins; C571801:follitropin alfa; D008596:Menotropins
keywords: Estradiol; Estrogen; Gonadotrophins; In vitro; Psychotic