title: Lobular breast carcinoma: a case of rare possible 18F-FDG PET/CT and bone scan false negative.
abstract: A patient with diffuse osteosclerotic bone metastases from invasive lobular breast carcinoma is presented with both F-FDG PET/CT and bone scans negative for hypermetabolic lesions. Skeletal metastases were documented by CT and bone marrow biopsy, and high increased CA 15-3 level was recorded. This case report points to the potential risk of false-negative FDG PET and bone scans examination in lobular carcinoma type.
authors.affiliation: From the Departments of *Nuclear Medicine, PET Unit, and †Pathology, Santa Maria della Misericordia Hospital, Rovigo, Italy; and ‡Department of Radiology, University of Southern California, Los Angeles, CA.
authors.forename: Anna Margherita
authors.initials: AM
authors.lastname: Maffione
authors.forename: Laura Camilla
authors.initials: LC
authors.lastname: Lisato
authors.forename: Annalisa
authors.initials: A
authors.lastname: Rasi
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Marzola
authors.forename: Patrick M
authors.initials: PM
authors.lastname: Colletti
authors.forename: Domenico
authors.initials: D
authors.lastname: Rubello
mesh_terms: D000368:Aged; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D018275:Carcinoma, Lobular / Q000000981:diagnostic imaging* / Q000473:pathology; D005188:False Negative Reactions; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18