title: [Prophylactic, preemptive and curative use of donor lymphocyte infusion in patients undergoing allogeneic stem cell transplantation: guidelines of the SFGM-TC].
abstract: In the attempt to harmonize clinical practices between different French transplantation centers, the French Society of Bone Marrow Transplantation and Cell Therapy (SFGM-TC) set up the fourth annual series of workshops which brought together practitioners from all member centers and took place in September 2013 in Lille. Here, we report our recommendations regarding the use of donor lymphocyte injection (DLI) in the prophylactic, pre-emptive and curative settings. This work has been limited to allogeneic stem cell transplantations from an HLA-matched (10/10) or -one antigen-mismatched (9/10) donor.
authors.affiliation: Service d'hématologie clinique, Hôtel-Dieu, CHU de Nantes, place Alexis-Ricordeau, 44035 Nantes cedex 01, France.
authors.forename: T
authors.initials: T
authors.lastname: Guillaume
authors.affiliation: Unité de soins intensifs - hématologie, centre Henri-Becquerel, 1, rue d'Amiens, 76000 Rouen cedex, France.
authors.forename: S
authors.initials: S
authors.lastname: Porcheron
authors.affiliation: Agence de la biomédecine, 1, avenue du Stade-de-France, 93212 Saint-Denis La Plaine cedex, France.
authors.forename: F
authors.initials: F
authors.lastname: Audat
authors.affiliation: Service d'hématologie, CHU d'Angers, 49033 Angers cedex 2, France.
authors.forename: N
authors.initials: N
authors.lastname: Bancillon
authors.affiliation: Service d'hématologie, hôpital Jean-Minjoz, boulevard Fleming, 25030 Besançon cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Berceanu
authors.affiliation: Service d'hématologie clinique, hôpital Sud, CHU d'Amiens, avenue Laënnec, 80054 Amiens cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Charbonnier
authors.affiliation: Maladies du sang, CHRU de Lille, rue Michel-Polonovski, 59037 Lille cedex, France.
authors.forename: R
authors.initials: R
authors.lastname: Dulery
authors.affiliation: Unité d'hémato-immunologie, hôpital Robert-Debré, 48, boulevard Sérurier, 75019 Paris, France.
authors.forename: N
authors.initials: N
authors.lastname: Edy
authors.affiliation: Unité de transplantation médullaire, institut Paoli-Calmettes, 232, boulevard Sainte-Marguerite, 13273 Marseille cedex 09, France.
authors.forename: J
authors.initials: J
authors.lastname: El Cheikh
authors.affiliation: Hôpital Estaing, 1, place Lucie-Aubrac, 63003 Clermont-Ferrand cedex 1, France.
authors.forename: E
authors.initials: E
authors.lastname: Hermet
authors.affiliation: Unité de greffe de moelle osseuse, CHRU de Strasbourg, 1, avenue Molière, 67098 Strasbourg, France.
authors.forename: N
authors.initials: N
authors.lastname: Maurer
authors.affiliation: Département d'hématologie clinique, CHRU de Montpellier, 80, rue Augustin-Fliche, 34295 Montpellier cedex, France.
authors.forename: F
authors.initials: F
authors.lastname: Paul
authors.affiliation: Service d'hématologie, hôpital d'instruction des armées Percy, 101, avenue Henri-Barbusse, 92140 Clamart, France.
authors.forename: J
authors.initials: J
authors.lastname: Konopacki-Potet
authors.affiliation: Service d'hématologie, centre hospitalier Dupuytren, 2, avenue Martin-Luther-King, 87042 Limoges cedex, France.
authors.forename: P
authors.initials: P
authors.lastname: Turlure
authors.affiliation: Maladies du sang, CHRU de Lille, rue Michel-Polonovski, 59037 Lille cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Wallart
authors.affiliation: EFS Nord de France, 21, rue Camille-Guérin, 59012 Lille cedex, France.
authors.forename: F
authors.initials: F
authors.lastname: Boulanger
authors.affiliation: Service d'hématologie, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75475 Paris cedex 10, France.
authors.forename: N
authors.initials: N
authors.lastname: Dhédin
authors.affiliation: Service d'hématologie adulte, hôpital Necker, 149, rue de Sèvres, 75743 Paris cedex 15, France.
authors.forename: F
authors.initials: F
authors.lastname: Suarez
authors.affiliation: Maladies du sang, CHRU de Lille, rue Michel-Polonovski, 59037 Lille cedex, France. Electronic address: sfgm-tc-iya@live.fr.
authors.forename: I
authors.initials: I
authors.lastname: Yakoub-Agha
mesh_terms: D006239:Haplotypes; D006650:Histocompatibility Testing; D006801:Humans; D017710:Lymphocyte Transfusion; D012008:Recurrence; D033581:Stem Cell Transplantation / Q000379:methods / Q000592:standards*; D009927:Tissue and Organ Procurement; D014184:Transplantation, Homologous / Q000379:methods / Q000592:standards*
keywords: Cell therapies; Curatif; Curative; Donor lymphocyte injection; Immunotherapy post-allogeneic transplantation; Immunothérapie post-allogreffe; Injection de lymphocytes du donneur; Preemptive; Prophylaxie; Prophylaxis; Préemptif; Thérapie cellulaire