title: Properties of novel composite meshes in chest wall reconstruction: A comparative animal study.
abstract: OBJECTIVE
  Novel composite meshes routinely used in laparoscopic hernia repair reportedly lead to fewer and less dense visceral adhesions and may provide a viable alternative in thoracic surgery as well.
  
  
  METHODS
  A total of 15 adult domestic pigs underwent full thickness chest wall resection and reconstruction with Parietene (polypropylene composite; PTE, n = 5), Parietex (polyester composite; PTX, n = 5) or Bard (purely polypropylene, n = 5) mesh. After an observation period of 90 days all animals were sacrificed, intrathoracic adhesions classified via thoracoscopy (VATS), meshes explanted and peak peal strength required for lung/mesh separation recorded.
  
  
  RESULTS
  Adhesions assessed through VATS-exploration were strongest in the PTX-Group while PTE and BM showed comparable results. Tensiometric analyses of peak peal strength confirmed lower values in BM than for PTE and PTX. Both composite materials showed good overall bioincorporation with post-surgical perigraft-fibrosis being strongest in BM.
  
  
  CONCLUSIONS
  We consider composite grafts a suitable alternative for chest wall reconstruction. They are characterized by good overall biointegration and limited perigraft-fibrosis, thus potentially facilitating redo-procedures, even though a hydrophilic coating per se does not appear to prevent intrathoracic adhesion formation.
authors.affiliation: Division of Cardiothoracic Surgery, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
authors.forename: Patrick
authors.initials: P
authors.lastname: Zardo
authors.affiliation: Division of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
authors.forename: Ruoyu
authors.initials: R
authors.lastname: Zhang
authors.affiliation: Division of Thoracic Surgery and Lung Support, Ibbenbüren General Hospital, Ibbenbüren, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Freermann
authors.affiliation: Division of Thoracic Surgery and Lung Support, Ibbenbüren General Hospital, Ibbenbüren, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Fischer
keywords: Composite grafts; chest wall reconstruction; chest wall resection