title: DNA gated photochromism and fluorescent switch in a thiazole orange modified diarylethene.
abstract: Thiazole orange-modified diarylethene (1) shows weak fluorescence but no photochromism in aqueous solution. When binding with DNA, the fluorescence of 1 is enhanced drastically and the photochromic reactivity is unlocked. This kind of DNA-responsive photoswitchable system can be used for imaging nucleic acids within cells.
authors.affiliation: Department of Chemistry, and Concerted Innovation Center of Chemistry for Energy Materials, Fudan University, 220 Handan Road, Shanghai 200433, P. R. China. yitao@fudan.edu.cn.
authors.forename: Keyin
authors.initials: K
authors.lastname: Liu
authors.forename: Ying
authors.initials: Y
authors.lastname: Wen
authors.forename: Ting
authors.initials: T
authors.lastname: Shi
authors.forename: Yi
authors.initials: Y
authors.lastname: Li
authors.forename: Fuyou
authors.initials: F
authors.lastname: Li
authors.forename: Yi-lei
authors.initials: YL
authors.lastname: Zhao
authors.forename: Chunhui
authors.initials: C
authors.lastname: Huang
authors.forename: Tao
authors.initials: T
authors.lastname: Yi
mesh_terms: D052160:Benzothiazoles / Q000737:chemistry*; D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry*; D005030:Ethylenes / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D018613:Microscopy, Confocal; D011804:Quinolines / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
chemical_list: D052160:Benzothiazoles; D005030:Ethylenes; D005456:Fluorescent Dyes; D011804:Quinolines; C051000:thiazole orange; D004247:DNA