title: P,N,N-pincer nickel-catalyzed cross-coupling of aryl fluorides and chlorides.
abstract: P,N,N-Pincer nickel complexes [Ni(Cl){N(2-R2PC6H4)(2'-Me2NC6H4)}] (R = Ph, 3a; R = Pr(i), 3b; R = Cy, 3c) were synthesized and their catalysis toward the Kumada or Negishi cross-coupling reaction of aryl fluorides and chlorides was evaluated. Complex 3a effectively catalyzes the cross-coupling of (hetero)aryl fluorides with aryl Grignard reagents at room temperature. Complex 3a also catalyzes the cross-coupling of (hetero)aryl chlorides and arylzinc reagents at 80 °C with low catalyst loadings and good functional group compatibility.
authors.affiliation: CAS Key Laboratory of Soft Matter Chemistry and Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, People's Republic of China. zxwang@ustc.edu.cn.
authors.forename: Dan
authors.initials: D
authors.lastname: Wu
authors.forename: Zhong-Xia
authors.initials: ZX
authors.lastname: Wang