title: Spontaneous Perforation as a First Presentation of Ileal Gastrointestinal Stromal Tumour (GIST) with Synchronous Breast Sarcoma.
abstract: Gastrointestinal Stromal Tumours (GIST's) are the most common mesenchymal neoplasms of the gastrointestinal tract. Majority of the GISTs are asymptomatic and often diagnosis is incidental. Synchronous second malignancies have been reported in patients with GIST. We report a case of 50-year-old female presenting with features of hollow viscous perforation, found to have ileal GIST with perforations along with a synchronous breast sarcoma. GIST with spontaneous perforation as its first clinical manifestation is rare. Synchronous occurrence of an ileal GIST with a breast sarcoma is unique and deserves reporting. This case report highlights the varied nature of clinical presentation of the GIST and also stresses on the importance of extensive search for the synchronous second malignancies in the extra abdominal sites as well.
authors.affiliation: Professor, Department of General Surgery, Regional Institute of Medical Sciences , Imphal, Manipur, India .
authors.forename: Bir Kumar
authors.initials: BK
authors.lastname: Sharma M
authors.affiliation: Junior Resident, Department of General Surgery, Regional Institute of Medical Sciences , Imphal, Manipur, India .
authors.forename: Arun Kumar
authors.initials: AK
authors.lastname: Barad
authors.affiliation: Junior Resident, Department of General Surgery, Regional Institute of Medical Sciences , Imphal, Manipur, India .
authors.forename: Kemba
authors.initials: K
authors.lastname: Padu
authors.affiliation: Junior Resident, Department of General Surgery, Regional Institute of Medical Sciences , Imphal, Manipur, India .
authors.forename: Sridartha
authors.initials: S
authors.lastname: Singh K
authors.affiliation: Professor, Department of General Surgery, Regional Institute of Medical Sciences , Imphal, Manipur, India .
authors.forename: Sudhir Chandra
authors.initials: SC
authors.lastname: Singh Th
keywords: Breast sarcoma; C-kit; Cajal cells; Gastrointestinal stromal tumour (GIST); Ileal perforation; Synchronous