title: Benign myoepithelioma in the intrathoracic trachea.
abstract: A 67-year-old woman who was followed as a patient with bronchial asthma for 1.5 years visited our hospital with progressive dyspnea. Although the chest radiography findings were normal, a chest computed tomography scan revealed a mass obliterating the intrathoracic tracheal lumen. The patient's symptoms disappeared immediately after tumor excision, and no recurrence was observed during a 1.5-year follow-up period. Microscopically, the tumor was composed of densely packed polygonal-, oval- and spindle-shaped cells that were positive for pan-cytokeratin, α-smooth muscle actin and p63. These pathological findings confirmed the diagnosis of benign myoepithelioma. Chest physicians should recognize that benign myoepithelioma can develop in the trachea, although it is very rare.
authors.affiliation: Department of Respiratory Medicine, National Hospital Organization, Ibarakihigashi National Hospital, Japan.
authors.forename: Akimasa
authors.initials: A
authors.lastname: Sekine
authors.forename: Yukio
authors.initials: Y
authors.lastname: Morishita
authors.forename: Koji
authors.initials: K
authors.lastname: Okudela
authors.forename: Yoshiya
authors.initials: Y
authors.lastname: Tsunoda
authors.forename: Yuki
authors.initials: Y
authors.lastname: Sumazaki
authors.forename: Toru
authors.initials: T
authors.lastname: Tanaka
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Takoi
authors.forename: Shih-Yuan
authors.initials: SY
authors.lastname: Lin
authors.forename: Yohei
authors.initials: Y
authors.lastname: Yatagai
authors.forename: Masaoki
authors.initials: M
authors.lastname: Shimanouchi
authors.forename: Toshinori
authors.initials: T
authors.lastname: Hashizume
authors.forename: Kenji
authors.initials: K
authors.lastname: Hayashihara
authors.forename: Takefumi
authors.initials: T
authors.lastname: Saito
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000378:metabolism; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D009208:Myoepithelioma / Q000175:diagnosis* / Q000378:metabolism; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014132:Trachea / Q000000981:diagnostic imaging / Q000473:pathology; D014134:Tracheal Neoplasms / Q000175:diagnosis* / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor