title: Complicated pediatric subglottic granular cell tumor with extensive intraluminal and extraluminal invasion.
abstract: Subglottic granular cell tumors (GCT) are rare, potentially life threatening benign tumors. Complete resection is necessary, yet care must be taken to preserve laryngeal function. We present the first description of a pediatric subglottic GCT with extensive invasion beyond the confines of the subglottis to include the vocal folds and central neck. Urgent endoscopic debulking avoided tracheotomy and facilitated extubation. Later, complete resection required hemithyroidectomy, laryngofissure and partial cricotracheal resection. We conclude that endoscopic debulking is an appropriate initial treatment. Transmural extension should be suspected in tumors larger than 1cm and warn of the need for tracheal resection.
authors.affiliation: Department of Otorhinolaryngology - Albert Einstein College of Medicine, Bronx, NY, United States; Steven and Alexandra Cohen Children's Medical Center, North Shore LIJ Health System, New Hyde Park, NY, United States.
authors.forename: Nathan J
authors.initials: NJ
authors.lastname: Gonik
authors.affiliation: Division of Thoracic Surgery, Department of Cardiovascular and Thoracic Surgery - Hofstra North Shore LIJ School of Medicine, New Hyde Park, NY, United States.
authors.forename: David
authors.initials: D
authors.lastname: Zeltsman
authors.affiliation: Department of Otorhinolaryngology - Albert Einstein College of Medicine, Bronx, NY, United States; Steven and Alexandra Cohen Children's Medical Center, North Shore LIJ Health System, New Hyde Park, NY, United States; Department of Otolaryngology - Hofsta North Shore LIJ School of Medicine, New Hyde Park, NY, United States. Electronic address: LSmith8@nshs.edu.
authors.forename: Lee P
authors.initials: LP
authors.lastname: Smith
mesh_terms: D000293:Adolescent; D065426:Cytoreduction Surgical Procedures / Q000379:methods*; D005260:Female; D016586:Granular Cell Tumor / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D007830:Larynx / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D009361:Neoplasm Invasiveness
keywords: Debulking; GCT; Granular cell; Pediatric; Subglottic; Tracheal resection