title: Goal-oriented treatment of pulmonary arterial hypertension.
abstract: OBJECTIVE
  To understand the rational of establishing a goal-oriented therapy for pulmonary arterial hypertension management.
  
  
  RESULTS
  During the last decades, the development of targeted therapies and the recognition of prognostic markers represented a major step for improving pulmonary arterial hypertension survival. Now, changing the strategy on using these compounds therapies might represent the best way to optimize treatment response.
  
  
  CONCLUSIONS
  Prespecified goals with regular reassessment should be incorporated as the routine practice for pulmonary arterial hypertension management to provide the best available treatment, aiming to improve or maintain every patient in a clinical and functional status that reflects better long-term survival.
authors.affiliation: Pulmonary Circulation Unit, Pulmonary Division, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, Brazil.
authors.forename: Carlos
authors.initials: C
authors.lastname: Jardim
authors.forename: Caio Julio Cesar
authors.initials: CJ
authors.lastname: Fernandes
authors.forename: Rogerio
authors.initials: R
authors.lastname: Souza
mesh_terms: D015444:Exercise; D006439:Hemodynamics; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy* / Q000503:physiopathology; D012129:Respiratory Function Tests