title: [The comparative pattern of neuromidin and magnetic stimulation influence on neuroplasticity in experimental traumatic neuropathy].
abstract: OBJECTIVE
  Traumatic neuropathies are among the most actual problems in neurology due to the severe neurological deficit in most cases and poor prognosis of recovery. We evaluated the effect of ipidacrin (cholinesterase inhibitor) and magnetic stimulation on neuroplastic axonal changes after experimental neurotmesis of rat's sciatic nerve.
  
  
  METHODS
  Animals (20 rats) were stratified into 3 groups. There was no treatment in the control group; in the second -group experimental animals underwent 3-5 min daily rhythmic magnetic stimulation (0,8-1T, 3 Hz) The third group of animals received intramuscular 0,035 mg of ipidacrin daily within 1 month.
  
  
  CONCLUSIONS
  Based on the received data on the restoration of myelin, axons, myelin nodes structure and lemmocyte ultrastructure), we have concluded that both magnetic stimulation and ipidacrin can trigger restorative and compensative processes in traumatic neuropathies.
authors.forename: S A
authors.initials: SA
authors.lastname: Zhivolupov
authors.forename: N A
authors.initials: NA
authors.lastname: Rashidov
authors.forename: L S
authors.initials: LS
authors.lastname: Onishchenko
authors.forename: I N
authors.initials: IN
authors.lastname: Samartsev
authors.forename: A V
authors.initials: AV
authors.lastname: Klimkin
authors.forename: A A
authors.initials: AA
authors.lastname: Iurin
mesh_terms: D000634:Aminoquinolines / Q000627:therapeutic use*; D000818:Animals; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use*; D004195:Disease Models, Animal; D055909:Magnetic Field Therapy; D008297:Male; D009473:Neuronal Plasticity; D051381:Rats; D011919:Rats, Inbred Strains; D012584:Sciatic Nerve / Q000293:injuries* / Q000502:physiology; D020426:Sciatic Neuropathy / Q000188:drug therapy / Q000503:physiopathology / Q000628:therapy*
chemical_list: D000634:Aminoquinolines; D002800:Cholinesterase Inhibitors; C049860:amiridine