title: Rational approaches to the treatment of hypertension: drug therapy-monotherapy, combination, or fixed-dose combination?
abstract: Blood pressure (BP) control is inadequate worldwide. Many clinical trials suggest that BP is not satisfactorily controlled using monotherapy in most patients. Free drug or fixed-dose combinations are other therapeutic options. The advantages and disadvantages for different treatment approaches are discussed in this review.
authors.affiliation: Ankara Numune Training and Research Hospital , Samanpazari, Ankara, Turkey.
authors.forename: Başol
authors.initials: B
authors.lastname: Canbakan
keywords: combination therapy; hypertension; treatment