title: ¹¹C-acetate PET/CT imaging: physiologic uptake, variants, and pitfalls.
abstract: (11)C-acetate PET is used in the assessment of various cardiologic and oncologic diseases. This article describes the physiologic uptake of (11)C-acetate and presents the common benign findings in different anatomic parts of the body. Salivary glands, tonsils, thyroid, meningeal tuberculoma, meningiomas, and macroadenomas of pituitary gland are sites of mild to moderate tracer uptake in the head and neck region. Parenchymal diseases of the lung and reactive and/or inflammatory mediastinal lymphadenopathies cause benign (11)C-acetate uptake in the thorax. Liver, spleen, pancreas, and rectum show an increased uptake. Urinary tract and prostate gland show faint tracer uptake.
authors.affiliation: Division of Nuclear Medicine, PET-PET/CT, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, Vienna A-1090, Austria. Electronic address: georgios.karanikas@meduniwien.ac.at.
authors.forename: Georgios
authors.initials: G
authors.lastname: Karanikas
authors.affiliation: PET-CT Center LINZ, Department of Nuclear Medicine and Endocrinology, St. Vincent's Hospital, Seilerstaette 4, Linz A-4020, Austria.
authors.forename: Mohsen
authors.initials: M
authors.lastname: Beheshti
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging; D000085:Acetates / Q000493:pharmacokinetics*; D002250:Carbon Radioisotopes / Q000493:pharmacokinetics*; D002490:Central Nervous System / Q000000981:diagnostic imaging; D006257:Head / Q000000981:diagnostic imaging; D006801:Humans; D009333:Neck / Q000000981:diagnostic imaging; D009369:Neoplasms / Q000000981:diagnostic imaging*; D010388:Pelvis / Q000000981:diagnostic imaging; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics*; D013909:Thorax / Q000000981:diagnostic imaging; D014018:Tissue Distribution; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D000085:Acetates; D002250:Carbon Radioisotopes; D019275:Radiopharmaceuticals
keywords: Acetate; PET-CT; Physiologic distribution; Pitfalls