title: [Evaluation of ovarian status in women who received anti-tumor therapy in childhood and adolescence].
abstract: The paper presents the results of a study of the ovarian reserve in young women who received treatment for malignant tumors in childhood and adolescence and are in complete clinical remission. The function of the reproductive system was evaluated by serum concentrations of gonadotropins, estradiol, anti-Müllerian hormone (AMH) and inhibin B. The results were compared to the treatment, patients' age at the beginning of therapy and at the time of the examination. AMH level in serum was the most informative indicator of ovarian reserve in patients treated for malignant tumors.
authors.forename: N V
authors.initials: NV
authors.lastname: Roshchina
authors.forename: E V
authors.initials: EV
authors.lastname: Tsyrlina
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Punanov
authors.forename: S A
authors.initials: SA
authors.lastname: Safonova
authors.forename: L M
authors.initials: LM
authors.lastname: Bershteĭn
authors.forename: E V
authors.initials: EV
authors.lastname: Kostromina
authors.forename: A P
authors.initials: AP
authors.lastname: Malinin
authors.forename: E V
authors.initials: EV
authors.lastname: Morozova
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D054304:Anti-Mullerian Hormone / Q000097:blood*; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D015415:Biomarkers / Q000097:blood; D001859:Bone Neoplasms / Q000628:therapy; D002648:Child; D004958:Estradiol / Q000097:blood*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006689:Hodgkin Disease / Q000628:therapy; D006801:Humans; D007265:Inhibins / Q000097:blood*; D007986:Luteinizing Hormone / Q000097:blood*; D008228:Lymphoma, Non-Hodgkin / Q000628:therapy; D009369:Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D009447:Neuroblastoma / Q000628:therapy; D012516:Osteosarcoma / Q000628:therapy; D010053:Ovary / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology / Q000528:radiation effects; D011237:Predictive Value of Tests; D011878:Radiotherapy / Q000009:adverse effects; D012512:Sarcoma, Ewing / Q000628:therapy; D009396:Wilms Tumor / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents; D015415:Biomarkers; C422364:inhibin B; D004958:Estradiol; D007265:Inhibins; D054304:Anti-Mullerian Hormone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone