title: Blood lactate measurement and interpretation in critically ill equine adults and neonates.
abstract: Admission blood lactate concentration is widely used as a prognostic indicator in equine medicine and can be a useful indicator of disease severity but typically fails to completely discriminate survivors from nonsurvivors. Increased admission lactate concentrations in adult horses typically return to normal within 12 to 24 hours. Lactate concentrations in neonatal foals are higher than adult concentrations for the first 24 to 72 hours of life. Serial measures reflecting both the magnitude and duration of hyperlactatemia might enable more accurate prognostication and provide insight into disease pathogenesis and could be a valuable therapeutic guide.
authors.affiliation: Faculty of Veterinary Science, Equine Centre, The University of Melbourne, 250 Princess Highway, Werribee, Victoria 3030, Australia. Electronic address: brett.tennent@unimelb.edu.au.
authors.forename: Brett
authors.initials: B
authors.lastname: Tennent-Brown
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D016638:Critical Illness; D006734:Horse Diseases / Q000097:blood*; D006736:Horses / Q000097:blood*; D019344:Lactic Acid / Q000097:blood*
chemical_list: D019344:Lactic Acid
keywords: Equine; Lactate; Lactate clearance; Serial measurement