title: [Basic features of the ISUP prostate carcinoma Gleason grading system: a preliminary analysis].
abstract: OBJECTIVE
  To explore the basic features of the prostate carcinoma Gleason grading system of the International Society of Urological Pathology (ISUP).
  
  
  METHODS
  We analyzed the means and proportions of the Gleason score (GS), primary grade (PG), secondary grade (SG) and third grade (TG) of 667 cases of prostate carcinoma.
  
  
  RESULTS
  The means of GS, PG, SG and TG were 7.06 +/- 1.10, 3.53 +/- 0.66, 3.53 +/- 0.72 and 4.30 +/- 0.96, respectively. The cases with GS 5, 6, 7, 8, 9 and 10 accounted for 0.4% (3/677), 37.2% (252/677), 34.4% (233/677), 13.7% (93/677), 12.0% (81/677) and 2.2% (15/677), respectively; those with GS < or = 6 and > or = 7 constituted 37.7% (255/677) and 62.3% (422/677); those with GS3 + 3, 4 + 3 and 3 + 4 made up 37.2% (252/677), 19.2% (130/677) and 15.2% (103/677); and the TG cases held 10.3% (70/677), including 30.0% (21/70) of grade 3, 10% (7/70) of grade 4 and 60.0% (42/70) of grade 5.
  
  
  CONCLUSIONS
  Our study showed a high proportion of GS, a low proportion of GS < or = 6, and a high proportion of GS > or = 7 in the ISUP prostate carcinoma Gleason grading system. TG of GS needs to be further understood.
authors.forename: Gong-Wei
authors.initials: GW
authors.lastname: Wang
authors.forename: Dan-Hua
authors.initials: DH
authors.lastname: Shen
mesh_terms: D006801:Humans; D008297:Male; D060787:Neoplasm Grading / Q000379:methods*; D011471:Prostatic Neoplasms / Q000473:pathology*