title: Phenolic components from the stem of Acanthopanax koreanum and their inhibitory effects on NF-kappa B.
abstract: Two novel phenolic glucosides (1-2), as well as seven known compounds (3-9), were isolated from the stem of Acanthopanax koreanum; their chemical structures were determined by chemical and spectroscopic methods and subsequently compared with previously reported data. Their inhibition of nuclear factor kappa B (NF-κB) was measured in human embryonic kidney (293T) cells by using an NF-κB luciferase assay.
authors.affiliation: a College of Pharmacy, Chungnam National University , Daejeon , Korea.
authors.forename: Ya Nan
authors.initials: YN
authors.lastname: Sun
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Xi Tao
authors.initials: XT
authors.lastname: Yan
authors.forename: Seo Young
authors.initials: SY
authors.lastname: Yang
authors.forename: Seok Bean
authors.initials: SB
authors.lastname: Song
authors.forename: Young Ho
authors.initials: YH
authors.lastname: Kim
mesh_terms: D028001:Eleutherococcus / Q000737:chemistry*; D015870:Gene Expression / Q000187:drug effects*; D057809:HEK293 Cells; D006801:Humans; D016328:NF-kappa B / Q000096:biosynthesis*; D010636:Phenols / Q000008:administration & dosage* / Q000737:chemistry / Q000302:isolation & purification; D018547:Plant Stems / Q000737:chemistry
chemical_list: D016328:NF-kappa B; D010636:Phenols
keywords: Acanthopanax koreanum; Araliaceae; NF-kappa B