title: The synthesis, characterization and optical properties of novel 2-acyl 6-arylindolizines.
abstract: A series of novel 2-acyl-6-aryl substituted indolizine derivatives was synthesized by a novel tandem reaction between 4-acyl-pyrrole-2-carbaldehyde derivatives and ethyl 4-bromo-3-arylbut-2-enoate under mild conditions. The compounds were characterized using IR, (1)H NMR (13)C NMR and HRMS. The crystal structure of 7a was determined using single crystal X-ray crystallography. The absorption results showed that compounds 7a-e presented their absorption maxima at ca. 270 nm, while compounds 7f and 7g with a larger conjugation system exhibited red-shifted absorption character (ca. 280 nm). Fluorescence spectra revealed that these compounds exhibited blue fluorescence (434-456 nm) in dilute solutions and showed quantum yields of fluorescence between 0.02 and 0.39 in dichloromethane.
authors.affiliation: School of Chemical Engineering, Taishan Medical University, Taian, Shandong 271016, PR China.
authors.forename: Yan Qing
authors.initials: YQ
authors.lastname: Ge
authors.affiliation: School of Chemical Engineering, Taishan Medical University, Taian, Shandong 271016, PR China.
authors.forename: Xue Yong
authors.initials: XY
authors.lastname: Gong
authors.affiliation: School of Chemical Engineering, Taishan Medical University, Taian, Shandong 271016, PR China.
authors.forename: Guang Jie
authors.initials: GJ
authors.lastname: Song
authors.affiliation: School of Chemical Engineering, Taishan Medical University, Taian, Shandong 271016, PR China. Electronic address: xqcao@tsmc.edu.cn.
authors.forename: Xiao Qun
authors.initials: XQ
authors.lastname: Cao
authors.affiliation: School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong 250100, PR China. Electronic address: jwwang@sdu.edu.cn.
authors.forename: Jian Wu
authors.initials: JW
authors.lastname: Wang
mesh_terms: D018360:Crystallography, X-Ray; D004583:Electrons; D007212:Indolizines / Q000138:chemical synthesis* / Q000737:chemistry*; D008752:Methylene Chloride / Q000737:chemistry; D008968:Molecular Conformation; D055620:Optical Phenomena; D012997:Solvents / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet
chemical_list: D007212:Indolizines; D012997:Solvents; D008752:Methylene Chloride
keywords: Fluorescence; Indolizine; Nitrogen-bridgehead; Synthesis; Tandem; UV absorption