title: Early modified functional hemispherectomy in a young infant with Ohtahara syndrome and hemimegalencephaly.
abstract: We report on the youngest infant treated with modified functional hemispherectomy at the age of 5 months for Ohtahara syndrome and hemimegalencephaly as underlying pathology, and we depict the favorable outcome regarding seizure control and psychomotor development. These results highlight the potential usefulness of early surgery in such conditions.
authors.affiliation: Neurosurgery Department, Saint Georges Hospital and University Medical Center, Balamand University, Beirut, Lebanon.
authors.forename: Antoine
authors.initials: A
authors.lastname: Nachanakian
authors.affiliation: Pediatric Neurology Unit, Saint Georges Hospital and University Medical Center, Balamand University, Beirut, Lebanon.
authors.forename: Ghassan
authors.initials: G
authors.lastname: Hmaimess
authors.affiliation: Neurosurgery Department, Saint Georges Hospital and University Medical Center, Balamand University, Beirut, Lebanon.
authors.forename: Antonios
authors.initials: A
authors.lastname: El-Helou
authors.affiliation: Neurosurgery Department, Saint Georges Hospital and University Medical Center, Balamand University, Beirut, Lebanon.
authors.forename: Moussa
authors.initials: M
authors.lastname: Alaywan
authors.affiliation: Radiology Department, Saint Georges Hospital and University Medical Center, Balamand University, Beirut, Lebanon.
authors.forename: Carmen
authors.initials: C
authors.lastname: Adem-Hachem
authors.affiliation: Neuropathology Unit, Brugmann University Hospital, and Children Academic Hospital, Université Libre de Bruxelles (U.L.B.), Brussels, Belgium Hazim.Kadhim@chu-brugmann.be.
authors.forename: Hazim
authors.initials: H
authors.lastname: Kadhim
mesh_terms: D001921:Brain / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D004569:Electroencephalography; D005500:Follow-Up Studies; D065705:Hemimegalencephaly / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D038421:Hemispherectomy; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D012640:Seizures / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D013577:Syndrome
keywords: Ohtahara syndrome; epilepsy surgery; hemimegalencephaly; hemispherectomy; seizure