title: Is there a binding deficit in working memory in patients with schizophrenia? A meta-analysis.
abstract: In schizophrenia (SZ), a specific binding deficit in working memory (WM) has not yet been demonstrated, given that studies with various methodologies were conducted and the results obtained were heterogeneous. Thus, a meta-analysis of 10 WM studies was performed. Effect sizes were calculated for binding and control conditions. Analyses disclosed significantly lower scores in SZ patients relative to controls for both binding and control conditions. In addition, analyses revealed no greater impairments for the binding condition than for the control condition in SZ patients. Our meta-analysis suggests that there is no specific deficit of binding in WM in SZ.
authors.affiliation: Centre de recherche, Institut universitaire en santé mentale de Montréal, Montreal, Quebec, Canada; Department of Psychiatry, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Grot
authors.affiliation: Centre de recherche, Institut universitaire en santé mentale de Montréal, Montreal, Quebec, Canada; Department of Psychiatry, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Potvin
authors.affiliation: Centre de recherche, Institut universitaire en santé mentale de Montréal, Montreal, Quebec, Canada; Department of Psychiatry, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada. Electronic address: david.luck@umontreal.ca.
authors.forename: David
authors.initials: D
authors.lastname: Luck
mesh_terms: D001245:Association Learning; D006801:Humans; D008570:Memory, Short-Term; D012044:Regression Analysis; D012565:Schizophrenic Psychology
keywords: Binding; Meta-analysis; Schizophrenia; Working memory