title: Osteogenic ability according to the decalcified modality of auto-tooth bone grafts in peri-implant defects in dogs.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the bone generation capacity of the autotransplantation material with clinical and histological analyses after controlled acid treatment conditions.
  
  
  METHODS
  Bony defects were formed in the femur. Then, autotransplantation material was grafted after hydroxyapatite-coated implant placement. Experimental groups were classified according to the acid treatment method: 2% H2SO4 (group 1), 2% HCl (group 2), 2% HNO3 (group 3), or 2% ethylenediaminetetraacetic acid (EDTA) (group 4).
  
  
  RESULTS
  The new bone formation area and bone-implant contact (BIC) of the autotransplantation materials were measured after 8 weeks. The new bone formation area in experimental groups 2, 3, and 4 were greater than that in the control group (no graft) and in experimental group 1 at 8 weeks, and the BIC of experimental group 4 was greater than that in the control group and in experimental group 1; these differences showed statistical significance (P < 0.05).
  
  
  CONCLUSIONS
  Auto-tooth bone treated with EDTA resulted in more effective bone formation in dogs' femurs than bone treated with other solutions.
authors.affiliation: *Resident, Department of Oral and Maxillofacial Surgery, School of Dentistry, Chosun University, Gwangju, Republic of Korea. †Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Chosun University, Gwangju, Republic of Korea. ‡Professor, Department of Pathology, School of Medicine, Chosun University, Gwangju, Republic of Korea. §Assistant Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Chosun University, Gwangju, Republic of Korea. **Associate Professor, Department of Dental Hygiene, Kangwon National University, Samcheok, Republic of Korea. ††Clinical doctor, Misomore Dental Clinic, Republic of Korea.
authors.forename: Han-Seung
authors.initials: HS
authors.lastname: Jang
authors.forename: Su-Gwan
authors.initials: SG
authors.lastname: Kim
authors.forename: Sung-Chul
authors.initials: SC
authors.lastname: Lim
authors.forename: Ji-Su
authors.initials: JS
authors.lastname: Oh
authors.forename: Mi-Ae
authors.initials: MA
authors.lastname: Jeong
authors.forename: Jin-Son
authors.initials: JS
authors.lastname: Kim
mesh_terms: D000818:Animals; D016025:Bone Transplantation; D002114:Calcinosis; D015921:Dental Implants; D004285:Dogs; D010012:Osteogenesis; D014070:Tooth
chemical_list: D015921:Dental Implants