title: The association of some genetic factors with pulmonary tuberculosis in Georgian and Azeri ethno groups.
abstract: Pulmonary Tuberculosis (TB) is still one of the major public health problems. Over the last half decade the significant problem is an increased ratio of drug-resistant TB cases. TB is as well the most significant infectious disease in the country of Georgia. Pulmonary tuberculosis is assessed as a complex infectious disease affected by both, environmental and genetic factors. Present study was undertaken to find out the correlation between pulmonary tuberculosis and erythrocyte blood groups antigens determinant alleles (ABO - r, p, q; Rh D+, Rh D- and MN - p, q) in two different, Georgian and Azeri, ethno groups. Immune-serological methods, direct reaction of universal monoclonal antibodies were used. Materials processed by biostatistician methods. The study had shown different correlation of pulmonary tuberculosis to erythrocyte blood groups determinant alleles in Georgian and Azeri ethno groups. In Georgian ethno group pulmonary TB correlates with ABO-r and p, Rh-D,+' and MN-p alleles, whether ABO-q, Rh-D,-' and MN-p in Azeri ethno group.
authors.affiliation: Batumi Shota Rustaveli State University, Batumi, Georgia.
authors.forename: R
authors.initials: R
authors.lastname: Khukhunaishvili
authors.affiliation: Batumi Shota Rustaveli State University, Batumi, Georgia.
authors.forename: S
authors.initials: S
authors.lastname: Tskvitinidze
authors.affiliation: Batumi Shota Rustaveli State University, Batumi, Georgia.
authors.forename: M
authors.initials: M
authors.lastname: Nagervadze
authors.affiliation: Batumi Shota Rustaveli State University, Batumi, Georgia.
authors.forename: L
authors.initials: L
authors.lastname: Akhvlediani
authors.affiliation: Batumi Shota Rustaveli State University, Batumi, Georgia.
authors.forename: M
authors.initials: M
authors.lastname: Koridze
mesh_terms: D000017:ABO Blood-Group System / Q000235:genetics*; D000483:Alleles; D001382:Azerbaijan; D005006:Ethnicity / Q000235:genetics; D056726:Genetic Association Studies; D005846:Georgia (Republic); D006801:Humans; D008951:MNSs Blood-Group System / Q000235:genetics*; D010641:Phenotype; D012204:Rh-Hr Blood-Group System / Q000235:genetics*; D018088:Tuberculosis, Multidrug-Resistant / Q000235:genetics* / Q000473:pathology; D014397:Tuberculosis, Pulmonary / Q000235:genetics* / Q000473:pathology
chemical_list: D000017:ABO Blood-Group System; D008951:MNSs Blood-Group System; D012204:Rh-Hr Blood-Group System