title: Vitiligo nonsurgical treatment: a review of latest treatment researches.
abstract: Vitiligo is a common depigmenting acquired disorder affecting about 1-2% of the world population, regardless of race, ethnic background, or gender. It is characterized by the appearance of milky white maculae because of a loss of melanocytes. The disfiguring nature of vitiligo causes high psychosocial morbidity. This is especially pronounced in populations with darker skin tone, likely because of the marked contrast. A variety of nonsurgical treatment regimens are currently employed in vitiligo. We reviewed the latest studies carried out on different nonsurgical treatment modalities used in vitiligo. All nonsurgical treatment aid to repigment or depigmentation the skin, however, many of them require a prolonged treatment course and may yield minimal results as well as carry unwanted side effects. There is a need for further research into the causes of vitiligo and into discovering better treatments.
authors.affiliation: Department of Dermatology, The Second Affiliated Hospital, College of Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.
authors.forename: Yanfei
authors.initials: Y
authors.lastname: Zhang
authors.forename: Jessini Soranambal
authors.initials: JS
authors.lastname: Mooneyan-Ramchurn
authors.forename: Nan
authors.initials: N
authors.lastname: Zuo
authors.forename: Yiguo
authors.initials: Y
authors.lastname: Feng
authors.forename: Shengxiang
authors.initials: S
authors.lastname: Xiao
mesh_terms: D000279:Administration, Cutaneous; D003131:Combined Modality Therapy; D003879:Dermatologic Agents / Q000008:administration & dosage*; D006801:Humans; D028022:Low-Level Light Therapy; D011701:PUVA Therapy; D010778:Photochemotherapy; D010789:Phototherapy / Q000379:methods; D012880:Skin Pigmentation / Q000187:drug effects* / Q000528:radiation effects*; D016896:Treatment Outcome; D014820:Vitiligo / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*
chemical_list: D003879:Dermatologic Agents
keywords: nonsurgical treatment; treatment; vitiligo