title: Exploiting endogenous anti-inflammatory pathways as a therapeutic approach to multiorgan inflammatory disease.
abstract: This Commentary highlights the article by Montero-Melendez et al, revealing novel protective properties of endogenous melanocortin receptor 3 on periodontal status in health and disease and suggesting a new genus of anti-arthritic bone-sparing therapeutics.
authors.affiliation: Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada. Electronic address: altapharm@hotmail.com.
authors.forename: John L
authors.initials: JL
authors.lastname: Wallace
mesh_terms: D000818:Animals; D001169:Arthritis, Experimental / Q000378:metabolism*; D001172:Arthritis, Rheumatoid / Q000378:metabolism*; D008297:Male; D010510:Periodontal Diseases / Q000378:metabolism*; D044104:Receptor, Melanocortin, Type 3 / Q000378:metabolism*
chemical_list: D044104:Receptor, Melanocortin, Type 3