title: Celebrating 20 years of evidence from the Cochrane Collaboration: what has been the impact of systematic reviews on nephrology?
abstract: It has been 20 years since the Cochrane Collaboration started the global effort to synthesize evidence to improve healthcare. Since 1997, the Cochrane Renal Group has produced over 100 systematic reviews that have collectively had an important impact on nephrology care, guidelines and policy. In this article, we reflect on the ongoing need for randomized trials and systematic reviews in contemporary nephrology and the achievements of the Cochrane Collaboration so far. We also describe some of the challenges in clinical research still faced by the nephrology community today.
authors.affiliation: Cochrane Renal Group, Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia University of Otago Christchurch, Christchurch, New Zealand.
authors.forename: Suetonia C
authors.initials: SC
authors.lastname: Palmer
authors.affiliation: Cochrane Renal Group, Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia Sydney School of Public Health, Sydney, Australia.
authors.forename: Jonathan C
authors.initials: JC
authors.lastname: Craig
authors.affiliation: Cochrane Renal Group, Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia Sydney School of Public Health, Sydney, Australia.
authors.forename: Ann
authors.initials: A
authors.lastname: Jones
authors.affiliation: Cochrane Renal Group, Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia Sydney School of Public Health, Sydney, Australia.
authors.forename: Gail
authors.initials: G
authors.lastname: Higgins
authors.affiliation: Cochrane Renal Group, Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia Sydney School of Public Health, Sydney, Australia.
authors.forename: Narelle
authors.initials: N
authors.lastname: Willis
authors.affiliation: Cochrane Renal Group, Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia Sydney School of Public Health, Sydney, Australia Fondazione Mario Negri Sud, Santa Maria Imbaro, Italy Diaverum Scientific Office, Lund, Sweden University of Bari, Bari, Italy Amedeo Avogadro University of Eastern Piedmont, Piedmont, Italy.
authors.forename: Giovanni F M
authors.initials: GF
authors.lastname: Strippoli
mesh_terms: D035843:Biomedical Research; D003299:Cooperative Behavior; D019317:Evidence-Based Medicine / Q000592:standards*; D017408:Guidelines as Topic; D006801:Humans; D007391:International Cooperation; D007674:Kidney Diseases / Q000628:therapy*; D009398:Nephrology / Q000592:standards*; D012196:Review Literature as Topic
keywords: evidence; meta-analysis; randomized trial; systematic review