title: Erythromycin- and copper-resistant Enterococcus hirae from marine sediment and co-transfer of erm(B) and tcrB to human Enterococcus faecalis.
abstract: An erythromycin-, copper- and cadmium-resistant isolate of Enterococcus hirae from marine sediment was shown to harbor the plasmid pRE25 and to co-transfer erm(B) and tcrB to Enterococcus faecalis JH2-2. These data highlight the scope for antibiotic resistance selection by the marine environment through heavy metals and its possible involvement in antibiotic-resistant enterococcal infections.
authors.affiliation: Department of Life and Environmental Sciences, Polytechnic University of Marche, Ancona, Italy. Electronic address: s.pasquaroli@univpm.it.
authors.forename: Sonia
authors.initials: S
authors.lastname: Pasquaroli
authors.affiliation: Department of Life and Environmental Sciences, Polytechnic University of Marche, Ancona, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Di Cesare
authors.affiliation: Department of Life and Environmental Sciences, Polytechnic University of Marche, Ancona, Italy.
authors.forename: Carla
authors.initials: C
authors.lastname: Vignaroli
authors.affiliation: Department of Life and Environmental Sciences, Polytechnic University of Marche, Ancona, Italy.
authors.forename: Giulia
authors.initials: G
authors.lastname: Conti
authors.affiliation: Department of Biomolecular Sciences sect. Toxicological, Hygiene, and Environmental Sciences, University of Urbino Carlo Bo - Urbino (PU), Italy.
authors.forename: Barbara
authors.initials: B
authors.lastname: Citterio
authors.affiliation: Department of Life and Environmental Sciences, Polytechnic University of Marche, Ancona, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Biavasco
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000235:genetics*; D003300:Copper / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial / Q000235:genetics; D016983:Enterococcus / Q000187:drug effects* / Q000235:genetics*; D013293:Enterococcus faecalis / Q000235:genetics*; D004917:Erythromycin / Q000494:pharmacology*; D019015:Geologic Sediments / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D014161:Transduction, Genetic
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D004917:Erythromycin; D003300:Copper
keywords: Antibiotic resistance; Enterococci; Heavy metals; Marine environment