title: [Study on process and principle of lactose grinding modification to decrease hygroscopic of Rhodiolae Crenulatae Radix et Rhizoma extract].
abstract: In this paper, Rhodiolae Crenulatae Radix et Rhizoma extract,with high hygroscopic,was selected as research model, while lactose was selected as modifiers to study the effect of the grinding modification method on the hygroscopic. Subsequently, particle size distribution, scannin electron microscopy, infrared spectroscopy and surface properties were adopted for a phase analysis. The results showed that the modified extract, prepared by Rhodiolae Crenulatae Radix et Rhizoma extract grinding 5 min with the same amount of lactose UP2, which hygroscopic initial velocity, acceleration, and critical relative humidity moisture were less than that of Rhodiolae Crenulatae Radix et Rhizoma extract and the mixture dramatically. In addition, compared with the mixture, the size distribution of modified extract was much less, the microstructure was also difference, while the infrared spectroscopy and surface properties were similar with that of lactose. It is the main principle that lactose particle adhered to the surface of Rhodiolae Crenulatae Radix et Rhizoma extract after grinding mofication to decress the moisture obviously.
authors.forename: Ding-Kun
authors.initials: DK
authors.lastname: Zhang
authors.forename: Fang
authors.initials: F
authors.lastname: Zhang
authors.forename: Jun-Zhi
authors.initials: JZ
authors.lastname: Lin
authors.forename: Li
authors.initials: L
authors.lastname: Han
authors.forename: Zhen-Feng
authors.initials: ZF
authors.lastname: Wu
authors.forename: Ying-Guang
authors.initials: YG
authors.lastname: Yang
authors.forename: Ming
authors.initials: M
authors.lastname: Yang
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D007785:Lactose / Q000737:chemistry; D010316:Particle Size; D027343:Rhizome / Q000737:chemistry*; D029771:Rhodiola / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013499:Surface Properties; D017155:Wettability
chemical_list: D004365:Drugs, Chinese Herbal; D007785:Lactose