title: Sporadic lymphoplasmacytic cholecystitis: a clinicopathologic entity.
abstract: OBJECTIVE
  To describe a sporadic form of lymphoplasmacytic cholecystitis (LPC), a condition known to occur in patients with chronic biliary tract disease.
  
  
  METHODS
  One year's worth of cholecystectomies was reviewed for sporadic cases of LPC. Histologic, radiologic, and clinical findings were reviewed and compared with noninflamed controls. Sporadic cases were also compared histologically with obstructive LPC cases.
  
  
  RESULTS
  Sporadic LPC made up 7% of cholecystectomies, had a male predominance (54.2%), and more often presented with clinical signs of acute inflammation compared with controls. Radiologic findings identified gallstones in 71.4% of patients. The second most common finding was unexplained extrahepatic biliary dilation. There were no unique histologic findings to separate sporadic cases from those associated with pancreatobiliary disease.
  
  
  CONCLUSIONS
  While obstructive LPC is traditionally described as acalculous, chronic cholecystitis, we show this inflammatory pattern occurs both in the presence of gallstones and outside of previously described disease categories. In addition, LPC occurs in a unique patient demographic (older men), often presenting similarly to acute cholecystitis.
authors.affiliation: From the University of Michigan Health System, Ann Arbor, MI. Suntrea.Hammer@utsouthwestern.edu.
authors.forename: Suntrea T G
authors.initials: ST
authors.lastname: Hammer
authors.affiliation: From the University of Michigan Health System, Ann Arbor, MI.
authors.forename: Henry D
authors.initials: HD
authors.lastname: Appelman
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002764:Cholecystitis / Q000175:diagnosis / Q000473:pathology*; D002908:Chronic Disease; D005260:Female; D005704:Gallbladder / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D055815:Young Adult
keywords: Chronic cholecystitis; Lymphoplasmacytic cholecystitis