title: Evaluation of the effect of green tea extract on the prevention of gingival bleeding after posterior mandibular teeth extraction: a randomized controlled trial.
abstract: Background. Removing tooth results in gingival bleeding. Several measures are taken to stop bleeding. In this study, the effect of green tea extract on cessation of bleeding and oozing after removing of mandibular molars was investigated. Methods. This was a randomized controlled clinical trial carried out on 62 patients who were referred for extraction of their mandibular molars. The volunteers were randomly and equally divided into treatment and control groups. In the first group, green tea extract-impregnated sterile gauze was used after removing the tooth while in the second group, green tea extract-free gauze was applied. Active bleeding and oozing monitoring was done every 5 minutes until cessation of bleeding and one hour after that, respectively. The results were compared using t-test. Results. The mean ± SD of bleeding duration in green tea group was significantly lower than control group (5.87 ± 1.76 versus 10.09 ± 3.61 minutes, P = 0.001). In addition, the number of people with oozing one hour after surgery was significantly lower in the green tea group (6 versus 29 persons, P = 0.001). Conclusion. This study showed that green tea extract contributes to significant decline in bleeding of the socket caused by tooth extraction as well as reduction of oozing.
authors.affiliation: Department of Clinical Pharmacy and Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran.
authors.forename: Rasool
authors.identifier: 0000-0001-9301-4732
authors.initials: R
authors.lastname: Soltani
authors.affiliation: Department of Oral and Maxillofacial Surgery, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Abbas
authors.initials: A
authors.lastname: Haghighat
authors.affiliation: Department of Clinical Pharmacy and Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran.
authors.forename: Mehrdad
authors.initials: M
authors.lastname: Fanaei
authors.affiliation: Department of Pharmacognosy, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran.
authors.forename: Gholamreza
authors.initials: G
authors.lastname: Asghari