title: Sequential asymptomatic enterovirus infections in a patient with major histocompatibility complex class II primary immunodeficiency.
abstract: Patients with primary immunodeficiencies are usually susceptible to enterovirus infections and have higher risks to develop severe clinical forms. We report a unique description of a boy with major histocompatibility complex class II (MHC-II) deficiency infected by 9 different enterovirus serotypes during a 2-year period, with very mild clinical symptoms, probably due to the immunoglobulin therapy he was receiving.
authors.affiliation: Laboratory of Clinical Virology, WHO Reference Laboratory on Poliomyelitis, Institut Pasteur de Tunis, Tunisia nadiadrisschaari@gmail.com henda.triki@pasteur.rns.tn.
authors.forename: Nadia
authors.initials: N
authors.lastname: Driss
authors.affiliation: Pediatrics Department, Bone Marrow Transplantation Center, Tunis, Tunisia.
authors.forename: Fethi
authors.initials: F
authors.lastname: Mellouli
authors.affiliation: Laboratory of Clinical Virology, WHO Reference Laboratory on Poliomyelitis, Institut Pasteur de Tunis, Tunisia.
authors.forename: Ahlem
authors.initials: A
authors.lastname: Ben Yahia
authors.affiliation: Laboratory of Clinical Virology, WHO Reference Laboratory on Poliomyelitis, Institut Pasteur de Tunis, Tunisia.
authors.forename: Henda
authors.initials: H
authors.lastname: Touzi
authors.affiliation: Laboratory of Immunology, Institut Pasteur de Tunis, Tunisia.
authors.forename: Mohamed-Ridha
authors.initials: MR
authors.lastname: Barbouche
authors.affiliation: Laboratory of Clinical Virology, WHO Reference Laboratory on Poliomyelitis, Institut Pasteur de Tunis, Tunisia nadiadrisschaari@gmail.com henda.triki@pasteur.rns.tn.
authors.forename: Henda
authors.initials: H
authors.lastname: Triki
authors.affiliation: Pediatrics Department, Bone Marrow Transplantation Center, Tunis, Tunisia.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Bejaoui
mesh_terms: D000293:Adolescent; D058070:Asymptomatic Diseases; D004770:Enterovirus / Q000145:classification / Q000302:isolation & purification*; D004769:Enterovirus Infections / Q000175:diagnosis* / Q000276:immunology*; D000949:Histocompatibility Antigens Class II / Q000235:genetics* / Q000276:immunology; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000150:complications* / Q000175:diagnosis*; D008297:Male; D065288:Serogroup
chemical_list: D000949:Histocompatibility Antigens Class II