title: [Death caused by heat stroke: case report].
abstract: BACKGROUND
  Heat stroke is the most dangerous among numerous disorders caused by elevated environmental temperature. It is characterized by an increased body temperature of over 40 degrees C, the dysfunction of the central nervous system and the development of multiple organ failure. The aim of this paper was to highlight problems in the clinical and post-mortal diagnosis of fatal heat stroke.
  
  
  METHODS
  A 20-year-old male was found unconscious on the street; on admission at the Emergency Center, Clinical Center of Serbia, Belgrade, he was in a coma. The body temperature of 40 degrees C was maintained despite the applied therapy, meningeal signs were negative, tachycardia with gallop rhythm, hypotension, bleeding from the nose and mouth, and presence of skin bruises.
  
  
  RESULTS
  highly elevated LDH and creatine kinase, elevated serum creatinine, AST, and signs of DIC. Lethal outcome occurred 6 hours after admission, and the case remained clinically unsolved. Autopsy showed signs of hemorrhagic diathesis, brain and pulmonary edema, and microscopic examination revealed general congestion, internal bleeding in various organs, cerebral edema, massive blood aspiration and pulmonary edema. Toxicological and bacteriological examinations were negative. Based on these findings and subsequently obtained data on the conditions at the workplace where the young man had a part-time job, it was concluded that the violent death was caused by heat stroke.
  
  
  CONCLUSIONS
  Since heat stroke is associated with a high mortality rate and high incidence of serious and permanent organ damage in survivors, it is important to make the diagnosis of heat stroke as quickly as possible and apply appropriate treatment. Misdiagnosis of heat stroke, and consequently inadequate treatment, with a potential fatal outcome for the patient, can be the reason for blaming doctors for the legal offense of medical malpractice in failing to administer first aid.
authors.forename: Slobodan
authors.initials: S
authors.lastname: Savić
authors.forename: Snezana
authors.initials: S
authors.lastname: Pavlekić
authors.forename: Djordje
authors.initials: D
authors.lastname: Alempijević
authors.forename: Jecmenica
authors.initials: J
authors.lastname: Dragan
mesh_terms: D001344:Autopsy; D003128:Coma / Q000473:pathology; D003643:Death; D017809:Fatal Outcome; D018883:Heat Stroke / Q000473:pathology*; D006801:Humans; D008297:Male; D055771:Serbia; D055815:Young Adult