title: Brain correlates of response inhibition in Internet gaming disorder.
abstract: OBJECTIVE
  The present study aimed to evaluate the brain correlates of response inhibition among subjects with Internet gaming disorder (IGD).
  
  
  METHODS
  For this purpose, 15 men with IGD for at least 1 year, and 15 controls with no history of IGD were recruited to perform the Go/Nogo task under functional magnetic resonance imaging investigation. Prior to scanning, the subjects were assessed using the Chen Internet Addiction Scale and the Barrett Impulsivity Scale.
  
  
  RESULTS
  The control group exhibited activation of the right supplement motor area (SMA), dorsolateral prefrontal cortex, and caudate for response inhibition. However, the IGD group had a higher impulsivity and lower activity of the right SMA/pre-SMA in comparison to the control group.
  
  
  CONCLUSIONS
  The results obtained suggest that dysfunctional activation of the SMA for response inhibition is one of the candidate mechanisms of IGD.
authors.affiliation: Department of Medical Imaging, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; Department of Radiology, Faculty of Medicine, College of Medicine, Kaohsiung, Taiwan.
authors.forename: Chiao-Yun
authors.initials: CY
authors.lastname: Chen
authors.forename: Mei-Feng
authors.initials: MF
authors.lastname: Huang
authors.forename: Ju-Yu
authors.initials: JY
authors.lastname: Yen
authors.forename: Cheng-Sheng
authors.initials: CS
authors.lastname: Chen
authors.forename: Gin-Chung
authors.initials: GC
authors.lastname: Liu
authors.forename: Cheng-Fang
authors.initials: CF
authors.lastname: Yen
authors.forename: Chih-Hung
authors.initials: CH
authors.lastname: Ko
mesh_terms: D000328:Adult; D016739:Behavior, Addictive / Q000503:physiopathology*; D001921:Brain / Q000503:physiopathology*; D001931:Brain Mapping; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007175:Impulsive Behavior / Q000502:physiology*; D007266:Inhibition, Psychological; D020407:Internet; D008279:Magnetic Resonance Imaging; D008297:Male; D009483:Neuropsychological Tests; D018910:Video Games; D055815:Young Adult
keywords: Internet gaming disorder; impulsivity; response inhibition; supplement motor area