title: [REM sleep behavior disorders in Parkinson's disease].
abstract: The article presents a literature review on REM sleep behavior disorder (RBD). The loss of REM atonia of sleep, such that patients act out the contents of their dreams, is described. The most important implication of research into this area is that patients with idiopathic RBD are at very high risk of developing synuclein-mediated neurodegenerative disease (Parkinson's disease, dementia with Lewy bodies and multiple system atrophy), with risk estimates that approximate 40-65% at 10 years. Thus, RBD is a reliable marker of prodromal synucleinopathy that open possibilities for neuroprotective therapy.
authors.affiliation: Kafedra nevrologii Rossiĭskoĭ meditsinskoĭ akademii postdiplomnogo obrazovaniia, Tsentr ékstrapiramidnykh zabolevaniĭ, Moskva.
authors.forename: E A
authors.initials: EA
authors.lastname: Liashenko
authors.forename: M G
authors.initials: MG
authors.lastname: Poluéktov
authors.forename: O S
authors.initials: OS
authors.lastname: Levin