title: Evaluation of malnutrition and its association with biochemical parameters in patients with end stage renal disease undergoing hemodialysis using subjective global assessment.
abstract: BACKGROUND
  Malnutrition is a common problem in patients with end stage renal disease (ESRD) undergoing hemodialysis that increases morbidity and mortality rate in them. Subjective global assessment (SGA) is a tool used by health care providers to assess nutritional status in these patients. In addition, biochemical parameters are used to assess the nutritional status in all people.
  
  
  OBJECTIVE
  In this study, we evaluated the nutritional status of patients with ESRD undergoing hemodialysis using SGA and assessed probable association between biochemical parameters and malnutrition in this population.
  
  
  METHODS
  Using SGA, the nutritional status of 105 patients (60 males and 45 females) of two dialysis centers in Sari, Iran, was evaluated during years 2007-2008. It is a semiquantitative scoring system that has seven variables derived from medical history and physical examination. The biochemical parameters including hemoglobin, albumin, cholesterol, BUN, and creatinine were also measured.
  
  
  RESULTS
  Among 105 patients, 98 (93.33%) patients consisted of 56 males and 42 females had mild to moderate malnutrition and 3 (2.86%) women had severe malnutrition. In addition, all of the patients without malnutrition were men. We found significant association between patient's sex and the SGA score (P = 0.03) but no significant association was seen between age and duration of hemodialysis with SGA score. In addition, we did not find significant association between the measured biochemical parameters and malnutrition.
  
  
  CONCLUSIONS
  According to high prevalence of malnutrition in our patients with ESRD undergoing hemodialysis, periodic assessment of nutritional status is necessary in them. Meanwhile we found SGA as the best tool to assess nutritional status in patients with ESRD undergoing hemodialysis, because it can recognize various degrees of malnutrition that may remain undetected by a single laboratory assessment.
authors.affiliation: Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, IR Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Espahbodi
authors.affiliation: Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, IR Iran.
authors.forename: Talayeh
authors.initials: T
authors.lastname: Khoddad
authors.affiliation: Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, IR Iran.
authors.forename: Leila
authors.initials: L
authors.lastname: Esmaeili
keywords: Biological Markers; Kidney Failure, Chronic; Malnutrition; Renal Dialysis