title: Reducing prostate cancer deaths: unsupported speculation about the androgen deprivation hypothesis.
abstract: The reduction in prostate cancer deaths in the European Randomized Study of Screening for Prostate Cancer is best explained by a stage migration in the intervention arm, resulting in earlier effective treatment of localized prostate cancer compared with controls.
authors.affiliation: James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, MD, USA. Electronic address: hcarter@jhmi.edu.
authors.forename: H Ballentine
authors.initials: HB
authors.lastname: Carter
mesh_terms: D000726:Androgen Antagonists / Q000627:therapeutic use*; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000097:blood*; D055088:Early Detection of Cancer; D006801:Humans; D008297:Male; D008403:Mass Screening; D017430:Prostate-Specific Antigen / Q000097:blood*; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000401:mortality*; D057832:Watchful Waiting
chemical_list: D000726:Androgen Antagonists; D018931:Antineoplastic Agents, Hormonal; D014408:Biomarkers, Tumor; D017430:Prostate-Specific Antigen