title: Spectrum of mucocutaneous manifestations in human immunodeficiency virus-infected patients and its correlation with CD4 lymphocyte count.
abstract: In this study, 100 HIV-positive cases (63 men, 37 women) with skin findings were included. The mean CD4 T cell count was 253 cells/mm(3). A total of 235 dermatological manifestations were seen. The common infectious dermatoses were candidiasis (21%), Staphylococcal skin infections (20%), dermatophytoses (14%) and herpes zoster (6%). Among the non-infectious dermatoses were papular pruritic eruptions (20%), xerosis/ichthyosis (20%) and seborrhoeic dermatitis (16%). Statistically significant association (p < 0.05) with CD4 T cell count was seen in pyodermas, dermatophytoses and papular pruritic eruptions. Adverse drug reactions, diffuse hair loss, straightening of hairs and pigmentary changes were also noted. Although there was an absence of Kaposi's sarcoma in our study, a case of verrucous carcinoma of penis was noted.
authors.affiliation: Department of Dermatology, Venereology and Leprosy, KS Hegde Medical Academy, Mangalore, India michelle@dr.com.
authors.forename: Michelle S
authors.initials: MS
authors.lastname: Fernandes
authors.affiliation: Department of Dermatology, Venereology and Leprosy, Fr Muller Medical College, Mangalore, India.
authors.forename: Ramesh M
authors.initials: RM
authors.lastname: Bhat
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications* / Q000453:epidemiology / Q000276:immunology; D000328:Adult; D018791:CD4 Lymphocyte Count; D002177:Candidiasis / Q000453:epidemiology; D012628:Dermatitis, Seborrheic / Q000453:epidemiology / Q000276:immunology; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology; D006562:Herpes Zoster / Q000453:epidemiology / Q000276:immunology; D006801:Humans; D007057:Ichthyosis / Q000453:epidemiology / Q000276:immunology; D016867:Immunocompromised Host; D007194:India / Q000453:epidemiology; D008297:Male; D015995:Prevalence; D011446:Prospective Studies; D011537:Pruritus / Q000453:epidemiology; D011711:Pyoderma; D012514:Sarcoma, Kaposi / Q000453:epidemiology / Q000276:immunology; D012720:Severity of Illness Index; D012871:Skin Diseases / Q000453:epidemiology* / Q000209:etiology / Q000276:immunology*
keywords: AIDS; CD4 T cell count; HIV; dermatology; immunosuppression; mucocutaneous manifestations; skin