title: Two new iridoids from Verbena officinalis L.
abstract: Two new iridoids, 3-(5-(methoxycarbonyl)-2-oxo-2H-pyran-3-yl)butanoic acid, named verbeofflin I (1), and 7-hydroxydehydrohastatoside (2), were isolated from the aerial part of Verbena officinalis L, along with three known iridoids, verbenalin (3), 3,4-dihydroverbenalin (4), hastatoside (5) by means of various column chromatography steps. The structures of these compounds were elucidated through analysis of their spectroscopic data obtained using 1D and 2D NMR and MS techniques. Verbeofflin I (1) is the new class of secoiridoid in the family Verbenaceae.
authors.affiliation: The MOE Key Laboratory for Standardization of Chinese Medicines and SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Shanghai R&D Center for Standardization of Chinese Medicines, Institute of Chinese Materia Medica of Shanghai University of Traditional Chinese Medicine, Cai Lun Road 1200, Zhangjiang, Shanghai 201203, China. shujc210@163.com.
authors.forename: Jicheng
authors.initials: J
authors.lastname: Shu
authors.affiliation: The MOE Key Laboratory for Standardization of Chinese Medicines and SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Shanghai R&D Center for Standardization of Chinese Medicines, Institute of Chinese Materia Medica of Shanghai University of Traditional Chinese Medicine, Cai Lun Road 1200, Zhangjiang, Shanghai 201203, China. chouguixinmsn@hotmail.com.
authors.forename: Guixin
authors.initials: G
authors.lastname: Chou
authors.affiliation: The MOE Key Laboratory for Standardization of Chinese Medicines and SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Shanghai R&D Center for Standardization of Chinese Medicines, Institute of Chinese Materia Medica of Shanghai University of Traditional Chinese Medicine, Cai Lun Road 1200, Zhangjiang, Shanghai 201203, China. wangzht@hotmail.com.
authors.forename: Zhengtao
authors.initials: Z
authors.lastname: Wang
mesh_terms: D002853:Chromatography, Liquid; D039823:Iridoids / Q000737:chemistry* / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D032412:Verbena / Q000737:chemistry*
chemical_list: D039823:Iridoids