title: Nanofibers as novel drug carrier--An overview.
abstract: Presently polymer nanofibers have received much attention due to their unique properties such as large surface area, high porosity, small pore size, superior mechanical properties and ease of addition of surface functionalities compared with any other material. Nanofibers particularly polymeric nanofiber prepared by electrospinning process can be used as carriers for the controlled drug delivery of bioactive molecules such as cytokines, growth factors, anticancer drugs, enzymes and certain vitamins. This article presents an overview of nanofibers, various techniques involved in fabrication of nanofibers, their characterization, parameters affecting electrospinning process and their applications.
authors.affiliation: a Department of Pharmaceutics , ISF College of Pharmacy , Moga , Punjab , India.
authors.forename: Asif
authors.initials: A
authors.lastname: Morie
authors.affiliation: a Department of Pharmaceutics , ISF College of Pharmacy , Moga , Punjab , India.
authors.forename: Tarun
authors.initials: T
authors.lastname: Garg
authors.affiliation: a Department of Pharmaceutics , ISF College of Pharmacy , Moga , Punjab , India.
authors.forename: Amit K
authors.initials: AK
authors.lastname: Goyal
authors.affiliation: a Department of Pharmaceutics , ISF College of Pharmacy , Moga , Punjab , India.
authors.forename: Goutam
authors.initials: G
authors.lastname: Rath
mesh_terms: D000970:Antineoplastic Agents / Q000493:pharmacokinetics; D016207:Cytokines / Q000493:pharmacokinetics; D003692:Delayed-Action Preparations / Q000138:chemical synthesis*; D004337:Drug Carriers / Q000138:chemical synthesis*; D004339:Drug Compounding / Q000379:methods; D055664:Electrochemical Techniques; D004798:Enzymes / Q000493:pharmacokinetics; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000493:pharmacokinetics; D057139:Nanofibers / Q000737:chemistry*; D016062:Porosity; D014815:Vitamins / Q000493:pharmacokinetics
chemical_list: D000970:Antineoplastic Agents; D016207:Cytokines; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D004798:Enzymes; D036341:Intercellular Signaling Peptides and Proteins; D014815:Vitamins
keywords: drug delivery; electrospinning; nanofiber; sensor devices