title: Endometriosis in association with Herlyn-Werner-Wunderlich syndrome.
abstract: OBJECTIVE
  To describe the clinical characteristics of patients with Herlyn-Werner-Wunderlich syndrome (HWWS) and explore the relationship between an obstructive genital abnormality and pelvic endometriosis.
  
  
  METHODS
  Case series.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  A total of 94 women with Herlyn-Werner-Wunderlich syndrome (HWWS).
  
  
  METHODS
  Retrospectively reviewed charts of patients diagnosed with HWWS and follow-up contact.
  
  
  METHODS
  Data for each patient regarding demographics, presenting symptoms, concomitant complications, and anatomic variations were obtained from operation notes and clinical records.
  
  
  RESULTS
  The occurrence of pelvic endometriosis was 19.15% (18/94) in patients with HWWS. All ovarian endometrial cysts (100%) occurred ipsilateral to the vaginal septum. Pelvic endometriosis was significantly more frequent in patients with complete hemivaginal obstructions (10/27, 37.0%) than those with incomplete obstructions (8/67, 11.9%).
  
  
  CONCLUSIONS
  One-fifth of patients with HWWS were susceptible to pelvic endometriosis, and all of the ovarian endometriotic cysts were ipsilateral to the vaginal septum. Pelvic endometriosis in adolescents appeared to be related to the obstructed genital abnormality. Vaginal septum resection should be the first step in treatment and surgery has an important role in the treatment of endometriosis and pelvic adhesion.
authors.affiliation: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
authors.forename: Jiali
authors.initials: J
authors.lastname: Tong
authors.affiliation: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People's Republic of China. Electronic address: zhu_julie@sina.com.
authors.forename: Lan
authors.initials: L
authors.lastname: Zhu
authors.affiliation: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
authors.forename: Na
authors.initials: N
authors.lastname: Chen
authors.affiliation: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
authors.forename: Jinghe
authors.initials: J
authors.lastname: Lang
mesh_terms: D000015:Abnormalities, Multiple / Q000453:epidemiology; D000293:Adolescent; D000328:Adult; D004715:Endometriosis / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007668:Kidney / Q000002:abnormalities; D059952:Pelvic Floor Disorders / Q000453:epidemiology*; D012189:Retrospective Studies; D013577:Syndrome; D014564:Urogenital Abnormalities / Q000453:epidemiology*; D014599:Uterus / Q000002:abnormalities; D014621:Vagina / Q000002:abnormalities; D055815:Young Adult
keywords: Endometriosis; hemivaginal septum; obstructive genital abnormality; uterus didelphys