title: Efficacy of ethanol ablation for thyroglossal duct cyst.
abstract: OBJECTIVE
  Ethanol ablation has been known as an effective, easy, and safe treatment of cystic thyroid lesions. The objective of the present study was to evaluate efficacy of ethanol ablation as a minimally invasive management of thyroglossal duct cyst (TGDC).
  
  
  METHODS
  Between January 2012 and July 2013, 9 TGDC patients were diagnosed and treated with ethanol ablation. We evaluated the treatment outcomes with the change of volume reduction and the improvement of symptomatic and cosmetic complaints and complications.
  
  
  RESULTS
  Initial mean tumor volume was 8.9 mL (range, 0.2-36.9 mL) in ultrasonography. The mean number of the treatment sessions was 1.7 (range, 1-3 sessions). At last follow-up, the mean volume of the treated thyroglossal duct cyst decreased significantly from 8.9 mL to 1.9 mL (P = .019; volume reduction rate = 76.6%). Treatment success rate was 77.8% (7/9). Mean symptoms and cosmetic-grading scores improved from 5.2 to 3.1 and from 5.3 to 3.1 (P = .062). No significant complications were observed during follow-up.
  
  
  CONCLUSIONS
  Ethanol ablation is a feasible and convenient procedure without surgical scars and hospitalization for TGDC patients. Favorable outcomes can be achieved without significant complications.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Dong-A University College of Medicine, Busan, Korea.
authors.forename: Dong Kun
authors.initials: DK
authors.lastname: Lee
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Dong-A University College of Medicine, Busan, Korea.
authors.forename: Ji Won
authors.initials: JW
authors.lastname: Seo
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Dong-A University College of Medicine, Busan, Korea.
authors.forename: Heon Soo
authors.initials: HS
authors.lastname: Park
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Dong-A University College of Medicine, Busan, Korea.
authors.forename: Myung Koo
authors.initials: MK
authors.lastname: Kang
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Dong-A University College of Medicine, Busan, Korea.
authors.forename: Ae Lan
authors.initials: AL
authors.lastname: Jang
authors.affiliation: Department of Radiology, Dong-A University College of Medicine, Busan, Korea.
authors.forename: Joon Hyung
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Dong-A University College of Medicine, Busan, Korea santa@dau.ac.kr hyungnz@damc.or.kr.
authors.forename: Jong Chul
authors.initials: JC
authors.lastname: Hong
mesh_terms: D000293:Adolescent; D000328:Adult; D015331:Cohort Studies; D000431:Ethanol / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D015911:Sclerotherapy / Q000379:methods*; D012997:Solvents / Q000008:administration & dosage*; D013955:Thyroglossal Cyst / Q000473:pathology / Q000628:therapy*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D012997:Solvents; D000431:Ethanol
keywords: ablation; ethanol; sclerotherapy; thyroglossal duct cyst