title: Monoterpenoid coumarins from the peels of Clausena lansium.
abstract: A phytochemical investigation on the peels of Clausena lansium (Lour.) Skeels led to the isolation of two new monoterpenoid coumarins, named clauslactone V (1) and clauslactone W (2), together with three known analogues (3-5). Their structures were elucidated by spectroscopic techniques (UV, IR, MS, 1D and 2D NMR). All the compounds were evaluated for hypoglycemic activity, and compounds 1-5 showed α-glucosidase inhibitory activity in vitro.
authors.affiliation: Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture (Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine), Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, P. R. China.
authors.forename: Hui-Dong
authors.initials: HD
authors.lastname: Deng
authors.affiliation: Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture (Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine), Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, P. R. China.
authors.forename: Wen-Li
authors.initials: WL
authors.lastname: Mei
authors.affiliation: Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture (Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine), Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, P. R. China.
authors.forename: Zhi-Kai
authors.initials: ZK
authors.lastname: Guo
authors.affiliation: Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture (Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine), Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, P. R. China.
authors.forename: Shuai
authors.initials: S
authors.lastname: Liu
authors.affiliation: Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture (Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine), Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, P. R. China.
authors.forename: Wen-Jian
authors.initials: WJ
authors.lastname: Zuo
authors.affiliation: Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture (Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine), Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, P. R. China.
authors.forename: Wen-Hua
authors.initials: WH
authors.lastname: Dong
authors.affiliation: Key Laboratory of Protection and Developmental Utilization of Tropical Crop Germplasm Resources, Ministry of Education, College of Horticulture and Landscape Architecture, Hainan University, Haikou, Hainan, P. R. China.
authors.forename: Shao-Peng
authors.initials: SP
authors.lastname: Li
authors.affiliation: Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture (Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine), Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, P. R. China.
authors.forename: Hao-Fu
authors.initials: HF
authors.lastname: Dai
mesh_terms: D054700:Clausena / Q000737:chemistry*; D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D005638:Fruit / Q000737:chemistry; D065089:Glycoside Hydrolase Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D007004:Hypoglycemic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D015394:Molecular Structure; D039821:Monoterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal; D000520:alpha-Glucosidases / Q000187:drug effects
chemical_list: D003374:Coumarins; D004365:Drugs, Chinese Herbal; D065089:Glycoside Hydrolase Inhibitors; D007004:Hypoglycemic Agents; D039821:Monoterpenes; C000597144:clauslactone V; C000597253:clauslactone W; D000520:alpha-Glucosidases