title: Reasons for calibration standard curve slope variation in LC-MS assays and how to address it.
authors.affiliation: Bioanalytical Sciences Department, Research & Development, Bristol-Myers Squibb Co, Route 206 & Province Line Road, Princeton, NJ 08543, USA.
authors.forename: Yue
authors.initials: Y
authors.lastname: Zhao
authors.forename: Guowen
authors.initials: G
authors.lastname: Liu
authors.forename: Jim X
authors.initials: JX
authors.lastname: Shen
authors.forename: Anne-Francoise
authors.initials: AF
authors.lastname: Aubry
mesh_terms: D002138:Calibration / Q000592:standards*; D002853:Chromatography, Liquid / Q000379:methods / Q000592:standards*; D003198:Computer Simulation; D006801:Humans; D016014:Linear Models; D013058:Mass Spectrometry / Q000379:methods / Q000592:standards*; D008956:Models, Chemical
keywords: LC–MS/MS; calibration standard curve; regulated bioanalysis; slope variation