title: [Application of functional magnetic resonance imaging in acupoint functional significance of encephalic region].
abstract: Literatures of study on acupoint functional effect of encephalic region with functional magnetic resonance imaging (fMRI) are collected from the database of China National Knowledge Information (CNKI) and Wan fang database. Analysis and comments are made respectively from the status quo of studies on combination of single acupoint, two acupoints and multiple acupoints under both physiological and pathological conditions. The results show that the corresponding encephalic regions can be specifically activated by acupuncture. And different regions can be activated by different acupoints. However, studies on single acupoint, two acupoints and three acupoints are the major researches carried out at present. It is still lack of observation on effect of commonly-used combinations in clinic. Moreover, the reliability of the research results are also affected by disunity of operations protocol, reinforcing or reducing manipulations, intensity or depth of stimulation and duration of needling retention. Therefore, it is necessary to establish a unified and standard operation protocol to strictly control the bias factors which may affect the result of research in the future, and take patients as the study target as much as possible, so as to further explore the central effect mechanism.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Su
authors.forename: Jian-Ming
authors.initials: JM
authors.lastname: Zhang
authors.forename: Ming
authors.initials: M
authors.lastname: Li
mesh_terms: D015669:Acupuncture Points; D015670:Acupuncture Therapy; D001921:Brain / Q000000981:diagnostic imaging* / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D011859:Radiography