title: A new ellagic acid glycoside and DNA topoisomerase IB inhibitory activity of saponins from Putranjiva roxburghii.
abstract: Chemical investigation of the stem bark and leaves of Putranjiva roxburghii has resulted in the isolation of a new ellagic acid glycoside (5) along with four saponins (1-4). The structures of the isolated compounds were established by detailed spectral analysis. Incidentally putranoside-A methyl ester (4) has been isolated for the first time from this species and the saponins (1-4) exhibited potent DNA topoisomerase IB inhibitory activity.
authors.forename: Ashish
authors.initials: A
authors.lastname: Kumar
authors.forename: Somenath Roy
authors.initials: SR
authors.lastname: Chowdhury
authors.forename: Tulika
authors.initials: T
authors.lastname: Chakrabarti
authors.forename: Hemanta K
authors.initials: HK
authors.lastname: Majumdarb
authors.forename: Tarun
authors.initials: T
authors.lastname: Jha
authors.forename: Sibabrata
authors.initials: S
authors.lastname: Mukhopadhyay
mesh_terms: D004610:Ellagic Acid / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019665:Euphorbiaceae / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D059004:Topoisomerase I Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D006027:Glycosides; D012503:Saponins; D059004:Topoisomerase I Inhibitors; D004610:Ellagic Acid