title: Surgical technique of double valve replacement in a patient with osteogenesis imperfecta.
abstract: Osteogenesis imperfecta (OI) is an inherited connective tissue disorder. Left ventricle dilation and valve insufficiency are complications in patients with OI and such patients are at high risk of mortality and complications related to bleeding and tissue friability during cardiac surgery. Valve dehiscence due to extreme friability of the annulus is a major complication of cardiac valve replacement with OI. We describe OI in a male patient who underwent double valve replacement with mechanical valves using a tissue protective method to prevent valve dehiscence.
authors.affiliation: Department of Cardiovascular Surgery, Graduate School of Medicine, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan. mtabata_wk@yahoo.co.jp.
authors.forename: Mizuki
authors.initials: M
authors.lastname: Sumi
authors.affiliation: Department of Cardiovascular Surgery, Graduate School of Medicine, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
authors.forename: Tsuneo
authors.initials: T
authors.lastname: Ariyoshi
authors.affiliation: Department of Cardiovascular Surgery, Graduate School of Medicine, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
authors.forename: Seiji
authors.initials: S
authors.lastname: Matsukuma
authors.affiliation: Department of Cardiovascular Surgery, Graduate School of Medicine, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
authors.forename: Shun
authors.initials: S
authors.lastname: Nakaji
authors.affiliation: Department of Cardiovascular Surgery, Graduate School of Medicine, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Hashizume
authors.affiliation: Department of Pathology, Graduate School of Medicine, Nagasaki University, Nagasaki, Japan.
authors.forename: Naoe
authors.initials: N
authors.lastname: Kinoshita
authors.affiliation: Department of Cardiovascular Surgery, Graduate School of Medicine, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
authors.forename: Kiyoyuki
authors.initials: K
authors.lastname: Eishi
mesh_terms: D001022:Aortic Valve Insufficiency / Q000601:surgery*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D008297:Male; D008944:Mitral Valve Insufficiency / Q000601:surgery*; D010013:Osteogenesis Imperfecta / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult
keywords: Heart valve prosthesis implantation; Heritable disorder; Myxomatous degeneration; Osteogenesis imperfecta; Tissue friability; Valve insufficiency