title: Another brick in the wall of needs for invasive ventilation?
abstract: Ventilator-induced lung injury and ventilator-induced diaphragmatic dysfunction are major complications in mechanically ventilated patients with acute respiratory failure. Invasive ventilation adds a further burden by increasing the risk of infections. An approach that protects both lung and diaphragm is pivotal. Mirabella and colleagues compared conventional controlled ventilation with a mode that combines several potentially lung-protective properties - non-invasively applied neurally adjusted ventilatory assist - in an animal experiment. This approach seemed to be as effective but potentially more lung-protective. Although the experimental setup and results cannot be translated directly to the clinical setting, they should motivate us to further study this innovative approach.
authors.forename: Michael
authors.initials: M
authors.lastname: Quintel
authors.forename: Onnen
authors.initials: O
authors.lastname: Moerer
mesh_terms: D055371:Acute Lung Injury / Q000503:physiopathology*; D000818:Animals; D011175:Positive-Pressure Respiration / Q000379:methods*; D055397:Ventilator-Induced Lung Injury / Q000517:prevention & control*