title: Chicken essence improves exercise performance and ameliorates physical fatigue.
abstract: Chicken essence (CE) is a liquid nutritional supplement made from cooking whole chickens. In traditional Chinese medicine, CE is used to support health, promote healing, increase metabolism, and relieve fatigue. However, few studies have examined the effect of CE on exercise performance and physical fatigue. We aimed to evaluate the potential beneficial effects of CE on fatigue and ergogenic functions following physical challenge in mice. Male ICR mice were divided into four groups to receive vehicle or CE by oral gavage at 0, 845, 1690, or 4225 mg/kg/day for 4 weeks. Exercise performance and anti-fatigue function were evaluated by forelimb grip strength, exhaustive swimming time, and levels of physical fatigue-related biomarkers serum lactate, ammonia, glucose, and creatine kinase (CK) after physical challenge. CE supplementation dose-dependently elevated endurance and grip strength. CE supplementation significantly decreased lactate, ammonia, and CK levels after physical challenge. Tissue glycogen content, an important energy source for exercise, was significantly increased with CE supplementation. In addition, CE supplementation had few subchronic toxic effects. The supplementation with CE can have a wide spectrum of bioactivities on health promotion, performance improvement and anti-fatigue.
authors.affiliation: Graduate Institute of Athletics and Coaching Science, National Taiwan Sport University, Taoyuan 33301, Taiwan. magicpica521@gmail.com.
authors.forename: Wen-Ching
authors.initials: WC
authors.lastname: Huang
authors.affiliation: Department of Nutrition and Health Sciences, Kainan University, Taoyuan 33857, Taiwan. cilin@mail.knu.edu.tw.
authors.forename: Ching-I
authors.initials: CI
authors.lastname: Lin
authors.affiliation: Graduate Institute of Sports Science, National Taiwan Sport University, Taoyuan 33301, Taiwan. chiu2295@yahoo.com.tw.
authors.forename: Chien-Chao
authors.initials: CC
authors.lastname: Chiu
authors.affiliation: Department of Food Science, Nutrition, and Nutraceutical Biotechnology, Shih Chien University, Taipei 10462, Taiwan. linyiting0617@gmail.com.
authors.forename: Yi-Ting
authors.initials: YT
authors.lastname: Lin
authors.affiliation: Department of Food Science, Nutrition, and Nutraceutical Biotechnology, Shih Chien University, Taipei 10462, Taiwan. eric29345876@gmail.com.
authors.forename: Wei-Kai
authors.initials: WK
authors.lastname: Huang
authors.affiliation: Department of Food Science, Nutrition, and Nutraceutical Biotechnology, Shih Chien University, Taipei 10462, Taiwan. maggieh@mail.usc.edu.tw.
authors.forename: Hui-Yu
authors.initials: HY
authors.lastname: Huang
authors.affiliation: Graduate Institute of Sports Science, National Taiwan Sport University, Taoyuan 33301, Taiwan. john5523@ntsu.edu.tw.
authors.forename: Chi-Chang
authors.initials: CC
authors.lastname: Huang
mesh_terms: D000641:Ammonia / Q000097:blood; D000818:Animals; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D002645:Chickens; D003402:Creatine Kinase / Q000097:blood; D019587:Dietary Supplements; D005221:Fatigue / Q000628:therapy*; D005552:Forelimb; D006003:Glycogen / Q000378:metabolism; D018737:Hand Strength / Q000502:physiology; D050152:Intra-Abdominal Fat; D019344:Lactic Acid / Q000097:blood; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D018482:Muscle, Skeletal / Q000378:metabolism; D009929:Organ Size; D010805:Physical Conditioning, Animal; D011202:Poultry Products; D059550:Toxicity Tests, Subchronic
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D019344:Lactic Acid; D000641:Ammonia; D006003:Glycogen; D003402:Creatine Kinase