title: Investigation of α-dicarbonyl compounds in baby foods by high-performance liquid chromatography coupled with electrospray ionization mass spectrometry.
abstract: Baby foods are exposed to elevated temperatures during processing treatments such as sterilization or spray drying. These treatments decompose sugars leading to the formation of α-dicarbonyl compounds that are of importance since they have been associated with several metabolic disorders. In this study, an analytical method based on high-performance liquid chromatography coupled with electrospray ionization mass spectrometry (HPLC-ESI-MS) was used to determine α-dicarbonyl compounds in baby foods. The method entailed aqueous extraction of α-dicarbonyl compounds from the samples and derivatization with o-phenylenediamine prior to chromatographic analysis. The results indicated that major degradation product was 3-deoxyglucosone in the samples including cereal-based infant formula, canned fruit and vegetable puree. Its concentration ranged between 3.9 and 827.1 mg/kg in infant formula and between 26.7 and 92.3 mg/kg in fruit puree samples. The concentrations of glucosone, 1-deoxyglucosone, 5-hydroxymethyl-2-furfural, furfural, glyoxal, methylglyoxal, and dimethylglyoxal levels were rather low.
authors.affiliation: Department of Food Engineering, Hacettepe University , Ankara 06640, Turkey.
authors.forename: Tolgahan
authors.initials: T
authors.lastname: Kocadağlı
authors.forename: Vural
authors.initials: V
authors.lastname: Gökmen
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D003847:Deoxyglucose / Q000031:analogs & derivatives* / Q000032:analysis; D005662:Furaldehyde / Q000032:analysis; D006037:Glyoxal / Q000032:analysis; D006801:Humans; D007225:Infant Food / Q000032:analysis*; D041943:Infant Formula / Q000737:chemistry; D007661:Ketoses / Q000032:analysis; D011765:Pyruvaldehyde / Q000032:analysis; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*
chemical_list: D007661:Ketoses; C017022:glucosone; D006037:Glyoxal; D011765:Pyruvaldehyde; D003847:Deoxyglucose; D005662:Furaldehyde; C016350:3-deoxyglucosone