title: Sedation and memories of patients subjected to mechanical ventilation in an intensive care unit.
abstract: OBJECTIVE
  To investigate the relationship between sedation and the memories reported by patients subjected to mechanical ventilation following discharge from the intensive care unit.
  
  
  METHODS
  This prospective, observational, cohort study was conducted with individuals subjected to mechanical ventilation who remained in the intensive care unit for more than 24 hours. Clinical statistics and sedation records were extracted from the participants' clinical records; the data relative to the participants' memories were collected using a specific validated instrument. Assessment was performed three months after discharge from the intensive care unit.
  
  
  RESULTS
  A total of 128 individuals were assessed, most of whom (84.4%) reported recollections from their stay in the intensive care unit as predominantly a combination of real and illusory events. The participants subjected to sedation (67.2%) at deep levels (Richmond Agitation-Sedation Scale [RASS] -4 and -5) for more than two days and those with psychomotor agitation (33.6%) exhibited greater susceptibility to occurrence of illusory memories (p>0.001).
  
  
  CONCLUSIONS
  The probability of the occurrence of illusory memories was greater among the participants who were subjected to deep sedation. Sedation seems to be an additional factor that contributed to the occurrence of illusory memories in severely ill individuals subjected to mechanical ventilation.
authors.affiliation: Hospital Universitário do Oeste do Paraná, Cascavel, PR, Brasil.
authors.forename: Jaquilene Barreto da
authors.initials: JB
authors.lastname: Costa
authors.affiliation: Universidade Estadual de Maringá, Maringá, PR, Brasil.
authors.forename: Sonia Silva
authors.initials: SS
authors.lastname: Marcon
authors.affiliation: Curso de Fisioterapia, Universidade Estadual do Oeste do Paraná, Cascavel, PR, Brasil.
authors.forename: Claudia Rejane Lima de
authors.initials: CR
authors.lastname: Macedo
authors.affiliation: Unidade de Terapia Intensiva, Hospital Universitário do Oeste do Paraná, Cascavel, PR, Brasil.
authors.forename: Amaury Cesar
authors.initials: AC
authors.lastname: Jorge
authors.affiliation: Unidade de Terapia Intensiva, Hospital Universitário do Oeste do Paraná, Cascavel, PR, Brasil.
authors.forename: Péricles Almeida Delfino
authors.initials: PA
authors.lastname: Duarte
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015331:Cohort Studies; D054810:Deep Sedation / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D007362:Intensive Care Units; D008297:Male; D008568:Memory / Q000502:physiology*; D008875:Middle Aged; D011446:Prospective Studies; D011595:Psychomotor Agitation / Q000453:epidemiology; D012121:Respiration, Artificial / Q000379:methods* / Q000523:psychology; D013997:Time Factors; D055815:Young Adult
chemical_list: D006993:Hypnotics and Sedatives