title: Detection of methicillin-resistant Staphylococcus aureus carrying the mecC gene in human samples in Slovenia.
abstract: SUMMARY Following the recognition of a mecC MRSA isolate from a patient hospitalized in the northeastern region of Slovenia, a national collection of 395 community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) isolates from 2006 to 2013 was screened. An additional six mecC MRSA strains were found and characterized as spa types t843, t9397 and t10009, and multilocus sequence type ST130. The low oxacillin minimum inhibitory concentrations and absence of the mecA gene make recognition of these MRSA strains problematical for diagnostic laboratories. In such strains the presence of mecC should be determined.
authors.affiliation: National Laboratory for Health,Environment and Food, Maribor,Slovenia.
authors.forename: U
authors.initials: U
authors.lastname: Dermota
authors.affiliation: University of Ljubljana,Veterinary Faculty, Institute of Microbiology and Parasitology, Ljubljana,Slovenia.
authors.forename: I
authors.initials: I
authors.lastname: Zdovc
authors.affiliation: National Laboratory for Health,Environment and Food, Maribor,Slovenia.
authors.forename: I
authors.initials: I
authors.lastname: Strumbelj
authors.affiliation: National Laboratory for Health,Environment and Food, Maribor,Slovenia.
authors.forename: I
authors.initials: I
authors.lastname: Grmek-Kosnik
authors.affiliation: National Laboratory for Health,Environment and Food, Maribor,Slovenia.
authors.forename: H
authors.initials: H
authors.lastname: Ribic
authors.affiliation: National Laboratory for Health,Environment and Food, Maribor,Slovenia.
authors.forename: M
authors.initials: M
authors.lastname: Rupnik
authors.affiliation: University of Ljubljana,Veterinary Faculty, Institute of Microbiology and Parasitology, Ljubljana,Slovenia.
authors.forename: M
authors.initials: M
authors.lastname: Golob
authors.affiliation: University of Ljubljana,Veterinary Faculty, Institute of Microbiology and Parasitology, Ljubljana,Slovenia.
authors.forename: U
authors.initials: U
authors.lastname: Zajc
authors.affiliation: French National Reference Centre for Staphylococci,Lyon, France and Hospices Civils de Lyon, Lyon,France.
authors.forename: M
authors.initials: M
authors.lastname: Bes
authors.affiliation: French National Reference Centre for Staphylococci,Lyon, France and Hospices Civils de Lyon, Lyon,France.
authors.forename: F
authors.initials: F
authors.lastname: Laurent
authors.affiliation: Institute of Microbiology and Immunology,University of Ljubljana,Faculty of Medicine, Ljubljana,Slovenia.
authors.forename: M
authors.initials: M
authors.lastname: Mueller-Premru
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000235:genetics*; D017714:Community-Acquired Infections / Q000453:epidemiology* / Q000382:microbiology; D004269:DNA, Bacterial / Q000032:analysis; D005260:Female; D005798:Genes, Bacterial; D006801:Humans; D008297:Male; D016106:Methicillin Resistance / Q000235:genetics; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects / Q000235:genetics*; D008826:Microbial Sensitivity Tests; D010068:Oxacillin / Q000494:pharmacology; D046915:Penicillin-Binding Proteins; D017422:Sequence Analysis, DNA; D017524:Slovenia / Q000453:epidemiology; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D004269:DNA, Bacterial; D046915:Penicillin-Binding Proteins; C487789:mecA protein, Staphylococcus aureus; D010068:Oxacillin
keywords: t10009