title: Non-toxigenic penicillin-resistant cutaneous C. diphtheriae infection: a case report and review of the literature.
abstract: Here, we report a case of non-toxigenic Corynebacterium diphtheriae in a previously healthy 14-year-old girl that was acquired in Ethiopia and presented locally. This is the first clinical case of penicillin-resistant C. diphtheriae in the UK. This is significant finding because penicillin is the recommended first-line agent for the prophylaxis against and treatment of C. diphtheriae in patients who are not allergic to penicillin.
authors.affiliation: University Hospitals of Leicester NHS Trust, Microbiology Department, Leicester Royal Infirmary, Leicester LE1 5WW, United Kingdom. Electronic address: rosemary.fitzgerald@uhl-tr.nhs.uk.
authors.forename: Rosemarie Philippa
authors.initials: RP
authors.lastname: FitzGerald
authors.affiliation: University Hospitals of Leicester NHS Trust, Microbiology Department, Leicester Royal Infirmary, Leicester LE1 5WW, United Kingdom; University Hospitals of Leicester NHS Trust, Infectious Diseases Department, Leicester Royal Infirmary, Leicester LE1 5WW, United Kingdom.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Rosser
authors.affiliation: University Hospitals of Leicester NHS Trust, Microbiology Department, Leicester Royal Infirmary, Leicester LE1 5WW, United Kingdom.
authors.forename: Dona Nelun
authors.initials: DN
authors.lastname: Perera
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003353:Corynebacterium diphtheriae / Q000302:isolation & purification*; D004165:Diphtheria / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D010403:Penicillin Resistance; D010406:Penicillins / Q000627:therapeutic use; D017192:Skin Diseases, Bacterial / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D010406:Penicillins
keywords: Corynebacterium diphtheriae; Non-toxigenic; Penicillin resistant