title: Bilateral laparoscopic gonadectomy in a patient with complete androgen insensitivity syndrome and bilateral sertoli-leydig cell tumor: a case report and brief review of the literature.
abstract: BACKGROUND
  Complete androgen insensitivity syndrome (previously called testicular feminization) is specified by a 46 XY karyotype and negative sex chromatin, bilateral undescended testes, female genitalia appearance, and lack of mullerian derivatives.
  
  
  METHODS
  A 28-year-old woman with complete (severe) androgen resistance underwent prophylactic laparoscopic bilateral gonadectomy because of the eventually increased risk of gonadal malignancy. Although the gonads appeared grossly normal, microscopic examination revealed bilateral well differentiated sertoli-leydig cell tumor (SLCT).
  
  
  CONCLUSIONS
  Our Medline search revealed that this is the first reported case of bilateral sertoli-leydig cell tumor (SLCT) in androgen insensitivity syndrome.
authors.affiliation: Department of Urology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Asl Zare
authors.affiliation: Department of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran.
authors.forename: Mahmood Reza
authors.initials: MR
authors.lastname: Kalantari
authors.affiliation: Department of Urology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran.
authors.forename: Amir Abbas
authors.initials: AA
authors.lastname: Asadpour
authors.affiliation: Department of Urology, Faculty of Medicine, Kerman University of Medical Sciences, Kerman, IR Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Kamalati
keywords: Androgen-Insensitivity Syndrome; Laparoscopy; Sertoli-Leydig Cell Tumor