title: [A literature review on Chinese medicine syndrome and syndrome elements of chronic fatigue syndrome].
abstract: OBJECTIVE
  To research the distribution characteristics of Chinese medicine (CM) syndrome and syndrome elements of chronic fatigue syndrome (CFS) by analyzing literature in recent 20 years.
  
  
  METHODS
  Relevant literature on treating CFS by syndrome differentiation of CM at home were retrieved by computer and manual ways. Database were established by using EpiData 3.1 to conduct frequency analysis of syndrome and syndrome elements.
  
  
  RESULTS
  The most common clinical syndromes were Xin-Pi deficiency syndrome, Gan stagnation Pi deficiency syndrome, Gan-Shen yin deficiency syndrome, Gan qi stagnation syndrome, and Pi-Wei qi deficiency syndrome. Disease locations were sequenced as Pi, Gan, Shen, and Xin. The clinical pathogenesis of CFS was characterized by deficiency of vital energy, complicated with intermingled excess and deficiency. Asthenia of healthy energy was mainly manifested as qi deficiency, blood deficiency, and yin deficiency, while excess of sthenia was mainly manifested as qi stagnation, phlegm dampness, and static blood.
  
  
  CONCLUSIONS
  Research of CM syndrome starting from syndrome elements can better unify and standardize clinical syndrome differentiation. Results of literature analysis can provide reference for further studies.
authors.forename: Min
authors.initials: M
authors.lastname: Peng
authors.forename: Hong-bo
authors.initials: HB
authors.lastname: Ma
authors.forename: Guo-min
authors.initials: GM
authors.lastname: Si
mesh_terms: D015673:Fatigue Syndrome, Chronic; D006801:Humans; D008516:Medicine, Chinese Traditional; D016711:Yang Deficiency; D016710:Yin Deficiency