title: Effect of malic enzyme on ethanol production by Synechocystis sp. PCC 6803.
abstract: We investigated effects of malic enzyme on ethanol production by Synechocystis sp. PCC 6803 under autotrophic conditions. Deletion of me, which encodes malic enzyme, decreased ethanol production, whereas its overexpression had no effect. Our results suggest that maintaining optimal malic enzyme activity controls ethanol production by Synechocystis sp. PCC 6803.
authors.affiliation: Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita, Osaka 565-0871, Japan; Japan Science and Technology Agency, Core Research for Evolutional Science and Technology (JST, CREST), 1-5 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: yoshikawa@ist.osaka-u.ac.jp.
authors.forename: Katsunori
authors.initials: K
authors.lastname: Yoshikawa
authors.affiliation: Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita, Osaka 565-0871, Japan; Japan Science and Technology Agency, Core Research for Evolutional Science and Technology (JST, CREST), 1-5 Yamadaoka, Suita, Osaka 565-0871, Japan; Department of Bioengineering, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8501, Japan. Electronic address: thirasawa@bio.titech.ac.jp.
authors.forename: Takashi
authors.initials: T
authors.lastname: Hirasawa
authors.affiliation: Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita, Osaka 565-0871, Japan; Japan Science and Technology Agency, Core Research for Evolutional Science and Technology (JST, CREST), 1-5 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: shimizu@ist.osaka-u.ac.jp.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Shimizu
mesh_terms: D000431:Ethanol / Q000378:metabolism*; D008291:Malate Dehydrogenase / Q000378:metabolism*; D046939:Synechocystis / Q000378:metabolism*
chemical_list: D000431:Ethanol; D008291:Malate Dehydrogenase; C030574:malate dehydrogenase (decarboxylating)
keywords: Bioproduction; Cyanobacteria; Ethanol; Malic enzyme; Synechocystis sp. PCC 6803