title: Orbital alveolar soft-part sarcoma: clinico-pathological profiles, management and outcomes.
abstract: OBJECTIVE
  To study the clinico-radiological and clinic-pathological features of orbital alveolar soft-part sarcomas (ASPS).
  
  
  METHODS
  We retrieved 9 cases of orbital ASPS. Histopathological and immunohistochemical features and clinico-radiological findings were evaluated.
  
  
  RESULTS
  Age at presentation varied from 1 to 31 years. Both, children and adults were affected. Proptosis was the most common clinical presentation. PAS-positive diastase-resistant crystals and granules were found in all cases. All patients received adjuvant radiotherapy. Two cases had positive surgical margins and were treated with additional adjuvant chemotherapy. None of the patients had recurrence or metastases till the last follow up.
  
  
  CONCLUSIONS
  Early diagnosis with a multidisciplinary, multimodal approach of treatment is quintessential in achieving a long disease-free survival in patients with ASPS.
authors.forename: Kaustubh
authors.initials: K
authors.lastname: Mulay
authors.forename: Mohammad Javed
authors.initials: MJ
authors.lastname: Ali
authors.affiliation: Ocular Oncology Service, L.V. Prasad Eye Institute, Hyderabad, Andhra Pradesh, India.
authors.forename: Santosh G
authors.initials: SG
authors.lastname: Honavar
authors.forename: Vijay Anand P
authors.initials: VA
authors.lastname: Reddy
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D019468:Disease Management; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D011859:Radiography; D012189:Retrospective Studies; D018234:Sarcoma, Alveolar Soft Part / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult