title: [Chemoradiotherapy for locally advanced cervical cancer].
abstract: Cervical cancer takes second place in morbidity and third place in mortality from gynecological cancer. Advanced stages among newly diagnosed cases is still large. The "gold standard" of treatment for locally advanced cervical cancer is chemoradiotherapy with cisplatin that results in a lower risk of death. Improvement of radiotherapy methods allowed to bring optimal dose to the primary tumor with the inclusion of regional metastasis areas with less risk of damage to surrounding healthy tissue and organs. The search for alternative combinations of cytostatics, modes of drug administration, adjuvant chemotherapy after chemoradiotherapy showed an increase in survival of patients with locally advanced cervical cancer.
authors.forename: I Ia
authors.initials: IIa
authors.lastname: Bazaeva
authors.forename: V A
authors.initials: VA
authors.lastname: Gorbunova
authors.forename: O A
authors.initials: OA
authors.lastname: Kravets
authors.forename: S V
authors.initials: SV
authors.lastname: Khokhlova
authors.forename: S V
authors.initials: SV
authors.lastname: Limareva
authors.forename: V O
authors.initials: VO
authors.lastname: Panov
authors.forename: O N
authors.initials: ON
authors.lastname: Strel'tsova
authors.forename: E V
authors.initials: EV
authors.lastname: Tarachkova
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D059248:Chemoradiotherapy / Q000379:methods; D059186:Chemoradiotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D002986:Clinical Trials as Topic; D019583:Dose Fractionation, Radiation; D004334:Drug Administration Schedule; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D016019:Survival Analysis; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000628:therapy*
chemical_list: D002945:Cisplatin; D005472:Fluorouracil