title: Association between dopa decarboxylase gene variants and borderline personality disorder.
abstract: Despite heritability estimates of 37-69%, research has identified few genetic risk variants for borderline personality disorder (BPD). The present collaborative candidate gene study of 987 BPD cases and 1110 healthy controls found an association between BPD and single nucleotide polymorphism rs12718541 in the dopa decarboxylase gene.
authors.affiliation: Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Untere Zahlbacher Str. 8, 55131 Mainz, Germany. Electronic address: arian.mobascher@unimedizin-mainz.de.
authors.forename: Arian
authors.initials: A
authors.lastname: Mobascher
authors.affiliation: Department of Psychosomatic Medicine, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Bohus
authors.affiliation: Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Untere Zahlbacher Str. 8, 55131 Mainz, Germany.
authors.forename: Norbert
authors.initials: N
authors.lastname: Dahmen
authors.affiliation: Department of Psychiatry, Campus Benjamin Franklin, Charité-Universitätsmedizin, Berlin, Germany.
authors.forename: Lydie
authors.initials: L
authors.lastname: Dietl
authors.affiliation: Department of Psychiatry, Ludwig-Maximilians University, Munich, Germany; Department of Psychiatry and Psychotherapy, Martin-Luther University Halle-Wittenberg, Germany.
authors.forename: Ina
authors.initials: I
authors.lastname: Giegling
authors.affiliation: Department of Psychosomatic Medicine, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Jungkunz
authors.affiliation: Department of Psychosomatic Medicine, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.
authors.forename: Nikolaus
authors.initials: N
authors.lastname: Kleindienst
authors.affiliation: Department of Psychosomatic Medicine, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Limberger
authors.affiliation: Department of Psychiatry, Ludwig-Maximilians University, Munich, Germany.
authors.forename: Eva
authors.initials: E
authors.lastname: Meisenzahl
authors.affiliation: Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.
authors.forename: Marcella
authors.initials: M
authors.lastname: Rietschel
authors.affiliation: Department of Psychiatry, Campus Benjamin Franklin, Charité-Universitätsmedizin, Berlin, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Roepke
authors.affiliation: Department of Psychosomatic Medicine, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Schmahl
authors.affiliation: Department of Psychiatry, Campus Benjamin Franklin, Charité-Universitätsmedizin, Berlin, Germany; Leibniz Institute for Neurobiology, Magdeburg, Germany.
authors.forename: Björn
authors.initials: B
authors.lastname: Schott
authors.affiliation: Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Untere Zahlbacher Str. 8, 55131 Mainz, Germany.
authors.forename: Cornelia E
authors.initials: CE
authors.lastname: Schwarze
authors.affiliation: Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Untere Zahlbacher Str. 8, 55131 Mainz, Germany.
authors.forename: André
authors.initials: A
authors.lastname: Tadić
authors.affiliation: Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.
authors.forename: Jens
authors.initials: J
authors.lastname: Treutlein
authors.affiliation: Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Untere Zahlbacher Str. 8, 55131 Mainz, Germany.
authors.forename: Friederike
authors.initials: F
authors.lastname: Vogel
authors.affiliation: Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.
authors.forename: Stephanie H
authors.initials: SH
authors.lastname: Witt
authors.affiliation: Department of Psychiatry, Ludwig-Maximilians University, Munich, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Zetzsche
authors.affiliation: Department of Psychiatry, Ludwig-Maximilians University, Munich, Germany; Department of Psychiatry and Psychotherapy, Martin-Luther University Halle-Wittenberg, Germany.
authors.forename: Dan
authors.initials: D
authors.lastname: Rujescu
authors.affiliation: Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Untere Zahlbacher Str. 8, 55131 Mainz, Germany.
authors.forename: Klaus
authors.initials: K
authors.lastname: Lieb
mesh_terms: D000328:Adult; D000483:Alleles; D001883:Borderline Personality Disorder / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics*; D016022:Case-Control Studies; D004296:Dopa Decarboxylase / Q000235:genetics*; D005260:Female; D014644:Genetic Variation; D006801:Humans; D008297:Male; D008875:Middle Aged; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*
chemical_list: D004296:Dopa Decarboxylase
keywords: Borderline personality disorder; Dopa decarboxylase; Single nucleotide polymorphism