title: Positivity to p-ANCA in patients with status epilepticus.
abstract: BACKGROUND
  Status epilepticus (SE) may occur in the setting of several internal or neurologic diseases. Anti-neutrophilic cytoplasmic antibodies (ANCA) are a group of Ig that may be observed in patients with different autoimmune disorders but are particularly associated with systemic vasculitis named ANCA-associated-vasculities (AAV). We herein report 3 patients with SE and positivity to p-ANCA.
  
  
  METHODS
  One patient had a catastrophic evolution and died 5 months after disease onset. The other two patients had a good outcome and remained seizure-free at 30 months and 5 years of follow-up respectively.
  
  
  CONCLUSIONS
  This report highlights the importance of considering ANCA dosage in patients with SE of unclear origin.
authors.forename: Edoardo
authors.initials: E
authors.lastname: Ferlazzo
authors.affiliation: Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy. a.gambardella@unicz.it.
authors.forename: Antonio
authors.initials: A
authors.lastname: Gambardella
authors.forename: Marina
authors.initials: M
authors.lastname: Bellavia
authors.forename: Sara
authors.initials: S
authors.lastname: Gasparini
authors.forename: Laura
authors.initials: L
authors.lastname: Mumoli
authors.forename: Angelo
authors.initials: A
authors.lastname: Labate
authors.forename: Vittoria
authors.initials: V
authors.lastname: Cianci
authors.forename: Concetta
authors.initials: C
authors.lastname: Russo
authors.forename: Umberto
authors.initials: U
authors.lastname: Aguglia
mesh_terms: D000293:Adolescent; D000328:Adult; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013226:Status Epilepticus / Q000097:blood / Q000276:immunology* / Q000473:pathology*
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic