title: Diagnosis and management of laryngo-pharyngeal reflux.
abstract: The aim of the present paper was to analyze laryngo-pharyngeal reflux (LPR) manifestations in ENT patients, and present a diagnostic and treatment algorithm for appropriate management. Retrospective chart review of 150 patients, who had initially presented with symptoms suggestive of LPR. Treatment included the administration of omeprazole 20 mg twice daily for at least 4 weeks. Unresponsive patients were also given metoclopramide 10 mg twice daily for four additional weeks, and the dose of omeprazole was increased to 40 mg twice daily, if they did not achieve complete symptom resolution. Only patients who became completely asymptomatic after LPR treatment were included in the study. As many as 18 % of patients attending an ENT outpatient department benefited from anti-reflux treatment. A need to clear the throat represented the most common symptom, whereas interarytenoid oedema/congestion was the most common finding on flexible naso-endoscopy (62.67 and 72.7 % of patients, respectively). The vast majority of patients responded after 4 weeks of treatment with omeprazole, however, as many as 32 % of LPR patients achieved complete symptom control after the initial 4 week trial period. LPR seems to be more common than previously reported in the literature. Appropriate management of LPR can prevent the symptomatic use of various medical treatments for related manifestations, and even surgical interventions, thus decreasing the overall patient morbidity.
authors.affiliation: ENT Department, Doctors Hospital and Medical Centre, Johar Town, Pakistan.
authors.forename: Khurshid H
authors.initials: KH
authors.lastname: Alam
authors.affiliation: ENT Department, Lister Hospital, Coreys Mill Lane, Stevenage, Hertfordshire, SG1 4AB UK ; 33 Wetherby Close, Stevenage, Hertfordshire, SG1 5RX UK.
authors.forename: Petros V
authors.initials: PV
authors.lastname: Vlastarakos
keywords: Gastro-esophageal; Hoarseness; Laryngeal; Proton pump inhibitors; Reflux; Treatment