title: Nanorods of a new metal-biomolecule coordination polymer showing novel bidirectional electrocatalytic activity and excellent performance in electrochemical sensing.
abstract: Metal organic coordination polymers (CPs), as most attractive multifunctional materials, have been studied extensively in many fields. However, metal-biomolecule CPs and CPs' electrochemical properties and applications were studied much less. We focus on this topic aiming at electrochemical biosensors with excellent performance and high biocompatibility. A new nanoscaled metal-biomolecule CP, Mn-tyr, containing manganese and tyrosine, was synthesized hydrothermally and characterized by various techniques, including XRD, TEM, EDS, EDX mapping, elemental analysis, XPS, and IR. Electrode modified with Mn-tyr showed novel bidirectional electrocatalytic ability toward both reduction and oxidation of H2O2, which might be due to Mn. With the assistance of CNTs, the sensing performance of Mn-tyr/CNTs/GCE was improved to a much higher level, with high sensitivity of 543 mA mol(-1) L cm(-2) in linear range of 1.00×10(-6)-1.02×10(-4) mol L(-1), and detection limit of 3.8×10(-7) mol L(-1). Mn-tyr/CNTs/GCE also showed fast response, high selectivity, high steadiness and reproducibility. The excellent performance implies that the metal-biomolecule CPs are promising candidates for using in enzyme-free electrochemical biosensing.
authors.affiliation: Jiangsu Key Laboratory of New Power Batteries, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Jiangsu Key Laboratory of Biomedical Materials, College of Chemistry and Materials Science, Nanjing Normal University, 1 Wenyuan Road, Nanjing 210023, China.
authors.forename: Jiao
authors.initials: J
authors.lastname: Yang
authors.affiliation: Jiangsu Key Laboratory of New Power Batteries, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Jiangsu Key Laboratory of Biomedical Materials, College of Chemistry and Materials Science, Nanjing Normal University, 1 Wenyuan Road, Nanjing 210023, China. Electronic address: zhoubo@njnu.edu.cn.
authors.forename: Bo
authors.initials: B
authors.lastname: Zhou
authors.affiliation: Analytical & Testing Center of Nanjing Normal University, Nanjing Normal University, 1 Wenyuan Road, Nanjing 210023, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Yao
authors.affiliation: Jiangsu Key Laboratory of New Power Batteries, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Jiangsu Key Laboratory of Biomedical Materials, College of Chemistry and Materials Science, Nanjing Normal University, 1 Wenyuan Road, Nanjing 210023, China.
authors.forename: Xiao-Qing
authors.initials: XQ
authors.lastname: Jiang
mesh_terms: D015374:Biosensing Techniques; D006861:Hydrogen Peroxide / Q000737:chemistry / Q000302:isolation & purification*; D008345:Manganese / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry; D008670:Metals / Q000138:chemical synthesis / Q000737:chemistry; D043942:Nanotubes / Q000737:chemistry; D037742:Nanotubes, Carbon / Q000737:chemistry; D010084:Oxidation-Reduction; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry; D014443:Tyrosine / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D008670:Metals; D037742:Nanotubes, Carbon; D011108:Polymers; D014443:Tyrosine; D008345:Manganese; D006861:Hydrogen Peroxide
keywords: Bidirectional electrocatalysis; Coordination polymer; Electrochemical sensing; Hydrogen peroxide determination; Manganese; Nanomaterials