title: Foreign- vs US-born Asians and the association of type I uterine cancer.
abstract: OBJECTIVE
  The purpose of this study was to determine the association of type I endometrioid uterine cancer in US-born vs immigrant Asian women.
  
  
  METHODS
  Data were obtained from the Surveillance, Epidemiology, and End Results Program from 2001-2009. Chi-squared, Kaplan-Meier, and binomial logistic regression analyses were used for statistics.
  
  
  RESULTS
  Of 4834 Asian women with uterine cancer, 62% were US-born and 38% were immigrants. Of these women, 2972 (61%) had type I (grade 1 or 2, endometrioid histologic type) uterine cancer. Compared with patients with type II disease (grade 3, clear cell and serous histologic type), patients with type I disease were younger (age 55 vs 59 years; P < .01) and had lower stage disease (90% vs 71%; P < .01). US-born Asian women had a significantly higher proportion of type I uterine cancers in contrast to their immigrant counterparts (65% vs 56%; P < .01). Of all immigrants, the proportion of type I cancers was lowest in Japanese women followed by Chinese and Filipino women, respectively (48% vs 52% vs 58%; P < .01). The 5-year disease-specific survivals of US-born vs immigrant Asian women with type I cancer was 92% for both groups. Over 3 time periods (2001-2003, 2004-2006, and 2007-2009), there was an increase in type I cancers among US-born Asian women (61% to 65% to 68%; P < .01).
  
  
  CONCLUSIONS
  US-born Asian women are more likely to be diagnosed with type I uterine cancer compared with immigrants. Over the study period, there was a trend towards an increase in type I cancers among US-born Asian women.
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics, Gynecology & Reproductive Sciences, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, School of Medicine, San Francisco, CA.
authors.forename: Elise
authors.initials: E
authors.lastname: Simons
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics, Gynecology & Reproductive Sciences, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, School of Medicine, San Francisco, CA; Division of Gynecologic Oncology, California Pacific and Palo Alto Medical Foundation Sutter Research Institute, Palo Alto, CA.
authors.forename: Kevin
authors.initials: K
authors.lastname: Blansit
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics, Gynecology & Reproductive Sciences, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, School of Medicine, San Francisco, CA.
authors.forename: Torie
authors.initials: T
authors.lastname: Tsuei
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics, Gynecology & Reproductive Sciences, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, School of Medicine, San Francisco, CA.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Brooks
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics, Gynecology & Reproductive Sciences, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, School of Medicine, San Francisco, CA.
authors.forename: Stefanie
authors.initials: S
authors.lastname: Ueda
authors.affiliation: Department of Radiation Oncology, Stanford Cancer Center, Stanford University, Stanford, CA.
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Kapp
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics, Gynecology & Reproductive Sciences, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, School of Medicine, San Francisco, CA; Division of Gynecologic Oncology, California Pacific and Palo Alto Medical Foundation Sutter Research Institute, Palo Alto, CA. Electronic address: chanjohn@sutterhealth.org.
authors.forename: John K
authors.initials: JK
authors.lastname: Chan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001208:Asia / Q000208:ethnology; D001213:Asian; D018269:Carcinoma, Endometrioid / Q000453:epidemiology*; D054242:Emigrants and Immigrants; D005260:Female; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies; D014594:Uterine Neoplasms / Q000453:epidemiology*; D055815:Young Adult
keywords: Asian; birthplace; endometrial cancer; ethnicity; type I cancer