title: Influence of short term exposure of TBT on the male reproductive activity in freshwater prawn Macrobrachium rosenbergii (De Man).
abstract: In the present study, the effect of tributyltin (TBT) on the histopathological and hormonal changes during spermatogenesis in freshwater prawn Macrobrachium rosenbergii was documented. Three experimental concentrations such as 10, 100 and 1,000 ng/L were selected and exposed to prawns for 45 days. After TBT exposure, the reproductive activities like sperm count and sperm length were decreased when compared with control. Further, abnormal structure of the seminiferous tubule, decrease in spermatozoa concentration, diminution of the seminiferous tubule membrane and the abundance of spermatocytes in the testis were noticed in treated prawns. Interestingly, radioimmunoassay clearly revealed the reduction of testosterone level in TBT exposed groups. Thus, TBT has considerably reduced the level of testosterone and caused the impairment of spermatogenesis in the freshwater male prawn M. rosenbergii.
authors.affiliation: Department of Environmental Biotechnology, Bharathidasan University, Trichy, 620 024, Tamil Nadu, India, revathi_uniomad@yahoo.co.in.
authors.forename: Peranandam
authors.initials: P
authors.lastname: Revathi
authors.forename: Palanisamy
authors.initials: P
authors.lastname: Iyapparaj
authors.forename: Lourduraj Arockia
authors.initials: LA
authors.lastname: Vasanthi
authors.forename: Natesan
authors.initials: N
authors.lastname: Munuswamy
authors.forename: Vimalanathan Arun
authors.initials: VA
authors.lastname: Prasanna
authors.forename: Jayaraj
authors.initials: J
authors.lastname: Pandiyarajan
authors.forename: Muthukalingan
authors.initials: M
authors.lastname: Krishnan
mesh_terms: D000818:Animals; D005618:Fresh Water; D006801:Humans; D008297:Male; D033541:Palaemonidae / Q000187:drug effects* / Q000502:physiology; D011863:Radioimmunoassay; D012098:Reproduction / Q000187:drug effects; D012671:Seminiferous Tubules / Q000187:drug effects; D013076:Sperm Count; D013091:Spermatogenesis / Q000187:drug effects*; D013094:Spermatozoa / Q000166:cytology / Q000187:drug effects; D013739:Testosterone / Q000378:metabolism; D014220:Trialkyltin Compounds / Q000633:toxicity*
chemical_list: D014220:Trialkyltin Compounds; D013739:Testosterone; C011559:tributyltin