title: Surveillance of chronic obstructive pulmonary disease in high-risk individuals by using regional lung cancer mass screening.
abstract: OBJECTIVE
  Patients with chronic obstructive pulmonary disease (COPD) are at risk for lung cancer; the diseases have common etiologies, including cigarette smoking. We aimed to clarify the effectiveness of COPD detection using a regional mass-screening program for lung cancer.
  
  
  METHODS
  A total of 7,067 residents of Togane, Chiba, Japan received lung cancer screening between May and July, 2011. We defined four groups of possible COPD candidates: group A (n=358), positive smoking history, positive chronic respiratory symptoms; group B (n=766), positive smoking history, positive lifestyle-related disease; group C (n=75), passive smoking history, positive chronic respiratory symptoms; and group D (n=301), passive smoking history, positive lifestyle-related disease. Candidates underwent on-site pulmonary function testing (PFT).
  
  
  RESULTS
  The criteria for COPD candidates were fulfilled in 1,686 of 7,067 individuals (23.9%); 1,500 participants underwent PFT (89%), and 171 (11.4%) were diagnosed with COPD. The overall COPD detection rate was 2.4%. The frequency of COPD was significantly higher in groups A and B than in groups C and D (P=0.048); however, the distribution of COPD grades was similar among the groups (P=0.372). Multiple logistic regression analysis identified male sex, age 60 years or greater, and positive smoking history as risk factors for COPD.
  
  
  CONCLUSIONS
  COPD screening using a community-based lung cancer-screening program may be effective for disease detection. Individuals who are 60 years of age or older with a positive smoking history should undergo PFT to detect COPD.
authors.affiliation: Chiba Foundation for Health Promotion and Disease Prevention, Chiba, Japan.
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Sekine
authors.affiliation: Chiba Foundation for Health Promotion and Disease Prevention, Chiba, Japan.
authors.forename: Ryoko
authors.initials: R
authors.lastname: Yanagibori
authors.affiliation: Chiba Foundation for Health Promotion and Disease Prevention, Chiba, Japan.
authors.forename: Kiminori
authors.initials: K
authors.lastname: Suzuki
authors.affiliation: Chiba Foundation for Health Promotion and Disease Prevention, Chiba, Japan.
authors.forename: Sonomi
authors.initials: S
authors.lastname: Sugiyama
authors.affiliation: Chiba Foundation for Health Promotion and Disease Prevention, Chiba, Japan.
authors.forename: Haruko
authors.initials: H
authors.lastname: Yamaji
authors.affiliation: Chiba Foundation for Health Promotion and Disease Prevention, Chiba, Japan.
authors.forename: Michiko
authors.initials: M
authors.lastname: Ishibashi
authors.affiliation: Chiba Foundation for Health Promotion and Disease Prevention, Chiba, Japan.
authors.forename: Takehiko
authors.initials: T
authors.lastname: Fujisawa
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008019:Life Style; D016015:Logistic Models; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000453:epidemiology; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D011237:Predictive Value of Tests; D015397:Program Evaluation; D029424:Pulmonary Disease, Chronic Obstructive / Q000175:diagnosis* / Q000453:epidemiology; D012129:Respiratory Function Tests; D018570:Risk Assessment; D012307:Risk Factors; D012720:Severity of Illness Index; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects; D013997:Time Factors
keywords: chronic obstructive pulmonary disease; lung neoplasms; mass screening; respiratory function tests