title: Microtubule self-organization via protein-RNA network crosstalk.
abstract: Microtubule plus-end tracking proteins are crucial for the regulation of microtubule dynamics. Preitner et al. report that one such protein, adenomatous polyposis coli (APC), also binds RNA and identify mRNAs encoding tubulin subunits within the brain APC-RNA interactome, suggesting a new mode of microtubule self-regulation.
authors.affiliation: Laboratory for Axon Growth and Regeneration, German Center for Neurodegenerative Diseases (DZNE), Ludwig-Erhard-Allee 2, 53175 Bonn, Germany. Electronic address: charlotte.coles@dzne.de.
authors.forename: Charlotte H
authors.initials: CH
authors.lastname: Coles
authors.affiliation: Laboratory for Axon Growth and Regeneration, German Center for Neurodegenerative Diseases (DZNE), Ludwig-Erhard-Allee 2, 53175 Bonn, Germany. Electronic address: frank.bradke@dzne.de.
authors.forename: Frank
authors.initials: F
authors.lastname: Bradke
mesh_terms: D025601:Adenomatous Polyposis Coli Protein / Q000378:metabolism*; D000818:Animals; D008870:Microtubules / Q000378:metabolism*; D055495:Neurogenesis; D016601:RNA-Binding Proteins / Q000378:metabolism*
chemical_list: D025601:Adenomatous Polyposis Coli Protein; D016601:RNA-Binding Proteins