title: Systemic endothelial function in primary open-angle glaucoma.
abstract: Objective. We aimed to assess peripheral vascular endothelial function in open-angle glaucoma (POAG) by measuring flow-mediated dilatation (FMD). Materials and Methods. The study included 20 cases with POAG (group 1, mean age 58.68 ± 13.3 years) and 30 healthy individuals (group 2, mean age 58.68 ± 13.6 years). In all cases, responses of endothelial function were assessed by a cardiologist through measurement of FMD following brachial artery occlusion. Results. Mean percent of FMD, an indicator of endothelial function, was found to be 11.9 ± 4.2% in group 1 and 12.3 ± 4.4% in group 2 (P = 0.86). Conclusion. No impairment in systemic vascular function of cases with POAG suggests that POAG could be a local disorder rather than being a component of systemic disease.
authors.affiliation: Department of Ophthalmology and Vision Science, Kayseri Training and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street, No. 78, 38010 Kayseri, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Atas
authors.affiliation: Department of Ophthalmology and Vision Science, Kayseri Training and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street, No. 78, 38010 Kayseri, Turkey.
authors.forename: Hasan Basri
authors.initials: HB
authors.lastname: Arifoglu
authors.affiliation: Department of Ophthalmology and Vision Science, Kayseri Training and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street, No. 78, 38010 Kayseri, Turkey.
authors.forename: Arzu Seyhan Karatepe
authors.initials: AS
authors.lastname: Hashas
authors.affiliation: Department of Cardiology, Kayseri Training and Research Hospital, 38010 Kayseri, Turkey.
authors.forename: Bahadır
authors.initials: B
authors.lastname: Sarli
authors.affiliation: Department of Ophthalmology and Vision Science, Kayseri Training and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street, No. 78, 38010 Kayseri, Turkey.
authors.forename: Suleyman
authors.initials: S
authors.lastname: Demircan
authors.affiliation: Department of Ophthalmology and Vision Science, Kayseri Training and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street, No. 78, 38010 Kayseri, Turkey.
authors.forename: Ayse
authors.initials: A
authors.lastname: Ozkose
authors.affiliation: Department of Ophthalmology and Vision Science, Kayseri Training and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street, No. 78, 38010 Kayseri, Turkey.
authors.forename: Altan
authors.initials: A
authors.lastname: Goktas