title: FDG-PET/CT in staging of clear cell odontogenic carcinoma.
abstract: Clear cell odontogenic carcinoma (CCOC) is a rare neoplasm; only 75 cases have been reported in the English language literature. They have a tendency for recurrence and a capacity to metastasize. There is very little known regarding the metabolic features of this tumour or the utility of fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) scans in the staging and follow-up of these tumours. We present two cases of CCOC with their relevant FDG-PET/CT scan findings. The first patient had primary CCOC of the mandible that was FDG-avid, and the other had recurrence of CCOC of the anterior mandible and superomedial orbit that was not FDG-avid. FDG uptake in CCOC appears to be variable. Although FDG-PET/CT is useful in other head and neck cancers and has benefits compared to other imaging modalities, further studies are needed to investigate the sensitivity of FDG-PET/CT in CCOC.
authors.affiliation: Department of Oral and Maxillofacial Surgery & Department of Nuclear Medicine and Specialised PET Services, Royal Brisbane Hospital, Queensland, Australia. Electronic address: ragukrishnamoorthy@gmail.com.
authors.forename: R
authors.initials: R
authors.lastname: Krishnamoorthy
authors.affiliation: Department of Oral and Maxillofacial Surgery & Department of Nuclear Medicine and Specialised PET Services, Royal Brisbane Hospital, Queensland, Australia.
authors.forename: A S
authors.initials: AS
authors.lastname: Ravi Kumar
authors.affiliation: Department of Oral and Maxillofacial Surgery & Department of Nuclear Medicine and Specialised PET Services, Royal Brisbane Hospital, Queensland, Australia.
authors.forename: M
authors.initials: M
authors.lastname: Batstone
mesh_terms: D000368:Aged; D001706:Biopsy; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008207:Lymphatic Metastasis; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D008441:Maxillary Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D064847:Multimodal Imaging; D009367:Neoplasm Staging; D009808:Odontogenic Tumors / Q000000981:diagnostic imaging* / Q000276:immunology* / Q000473:pathology / Q000601:surgery; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18