title: Iridium-catalyzed oxidative olefination of furans with unactivated alkenes.
abstract: The oxidative coupling of arenes and alkenes is an attractive strategy for the synthesis of vinylarenes, but reactions with unactivated alkenes have typically occurred in low yield. We report an Ir-catalyzed oxidative coupling of furans with unactivated olefins to generate branched vinylfuran products in high yields and with high selectivities with a second alkene as the hydrogen acceptor. Detailed mechanistic experiments revealed catalyst decomposition pathways that were alleviated by the judicious selection of reaction conditions and application of new ligands.
authors.affiliation: Division of Chemical Sciences, Lawrence Berkeley National Laboratory, and Department of Chemistry, University of California , Berkeley, California 94720, United States.
authors.forename: Christo S
authors.initials: CS
authors.lastname: Sevov
authors.forename: John F
authors.initials: JF
authors.lastname: Hartwig