title: New enhanced and effective method for staging cancer to detect lymph nodes after fat-dissociation.
abstract: Pathologic staging is a key factor in the treatment and outcome of cancer patients, and lymph node status plays a pivotal role in this staging process. Several methods of lymph node assessment, such as the fat clearance, Schwartz solution and GEWF solution, are unpopular as they require a significant amount of time (1‑9 days) to clear the fat of the resected mesentery and to visualize the lymph nodes. In the present study, we discussed a more simple and effective method, called the fat‑dissociation method, which clears the fat using enzymes and allows for easy identification of lymph nodes around vessels. This new procedure facilitates precise staging of cancer which directs the post-operative treatment plan.
authors.affiliation: Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
authors.forename: Shiki
authors.initials: S
authors.lastname: Fujino
authors.affiliation: Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
authors.forename: Norikatsu
authors.initials: N
authors.lastname: Miyoshi
authors.affiliation: Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Ohue
authors.affiliation: Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
authors.forename: Shingo
authors.initials: S
authors.lastname: Noura
authors.affiliation: Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Tomita
authors.affiliation: Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
authors.forename: Masahiko
authors.initials: M
authors.lastname: Yano
authors.affiliation: Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
authors.forename: Masato
authors.initials: M
authors.lastname: Sakon
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism*; D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008643:Mesentery / Q000378:metabolism*; D008875:Middle Aged; D009367:Neoplasm Staging