title: Ciprofloxacin-induced tendinopathy of the gluteal tendons.
abstract: Fluoroquinolone-induced tendinopathy most commonly affects the Achilles tendon; however, involvement of several other tendons has been described. This is a case report of ciprofloxacin-induced tendinopathy of the gluteal tendons with MRI findings. An obese 25-year-old woman with no significant past medical history was diagnosed with acute pyelonephritis and was treated with intravenous ciprofloxacin. Shortly after her first dose of ciprofloxacin, she developed severe left hip pain and decreased range of motion. MRI of the hips showed bilateral tendinopathy of the gluteal muscle insertion. A diagnosis of ciprofloxacin-induced tendinopathy was made based on her MRI and a Naranjo score of 7. Ciprofloxacin was stopped and her pain quickly resolved. Fluoroquinolones cause tendinopathy in 0.14 % to 0.4 % of patients using these agents. Fluoroquinolone-associated tendinopathy is a serious adverse reaction that can affect many tendons and should be considered in any patient presenting with new musculoskeletal complaints and in whom there is a history of fluoroquinolone use within the preceding 6 months.
authors.affiliation: Department of Internal Medicine, University of California at Davis Internal Medicine Residency Program, 3100 PSSB 4150 V St., Sacramento, CA, 95817, USA.
authors.forename: Kaumakaokalani
authors.initials: K
authors.lastname: Shimatsu
authors.forename: Somasundaram
authors.initials: S
authors.lastname: Subramaniam
authors.forename: Helen
authors.initials: H
authors.lastname: Sim
authors.forename: Paul
authors.initials: P
authors.lastname: Aronowitz
mesh_terms: D000208:Acute Disease; D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002081:Buttocks; D002939:Ciprofloxacin / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D011704:Pyelonephritis / Q000188:drug therapy; D052256:Tendinopathy / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin