title: Which patients have greatest need for elvitegravir/cobicistat/ emtricitabine/tenofovirDF-based therapy?
abstract: Elvitegravir/cobicistat/emtricitabine/tenofovirDF (EVG/COBI/FTC/TDF) is the new single-tablet, fixed-dose formulation containing an integrase strand transfer inhibitor recently approved as antiretroviral treatment. In this paper we analysed its use and advantages in naïve and experienced HIV-infected patients and we focused on special populations in which EVG/COBI/FTC/TDF could be a suitable option. Furthermore the manuscript reports the recent patent of EVG which may have an influence on the management of HIV-infected patients in the next future.
authors.forename: Antonio
authors.initials: A
authors.lastname: Di Biagio
authors.forename: Roberta
authors.initials: R
authors.lastname: Prinapori
authors.forename: Lucia
authors.initials: L
authors.lastname: Taramasso
authors.forename: Giulia
authors.initials: G
authors.lastname: Gustinetti
authors.forename: Laura
authors.initials: L
authors.lastname: Sticchi
authors.forename: Bianca
authors.initials: B
authors.lastname: Bruzzone
authors.affiliation: InfectiousDiseases Unit, IRCCS A.O.U. San Martino- IST, Genoa, Italy, Largo R. Benzi, 10, 16132 Genoa, Italy. antonio.dibiagio@hsanmartino.it.
authors.forename: Claudio
authors.initials: C
authors.lastname: Viscoli
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D002219:Carbamates / Q000627:therapeutic use*; D000069547:Cobicistat; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004338:Drug Combinations; D000068679:Emtricitabine; D015658:HIV Infections / Q000188:drug therapy*; D015497:HIV-1 / Q000187:drug effects; D006801:Humans; D010330:Patents as Topic; D010757:Phosphorous Acids / Q000627:therapeutic use*; D015363:Quinolones / Q000627:therapeutic use*; D013844:Thiazoles / Q000627:therapeutic use*
chemical_list: C574165:9-(2-((bis(pivaloyloxymethoxy)phosphinoyl)methoxy)propyl)adenine; D019380:Anti-HIV Agents; D002219:Carbamates; D004338:Drug Combinations; D010757:Phosphorous Acids; D015363:Quinolones; D013844:Thiazoles; D003841:Deoxycytidine; C509700:elvitegravir; D000068679:Emtricitabine; D000225:Adenine; D000069547:Cobicistat