title: Human papillomavirus (HPV) vaccination and subsequent sexual behaviour: evidence from a large survey of Nordic women.
abstract: OBJECTIVE
  To assess whether recipients and non-recipients of the human papillomavirus (HPV) vaccine subsequently differ in terms of sexual risk taking behaviour.
  
  
  METHODS
  Cross-sectional survey. Sequential analyses constructed from self-reported age at vaccination, age at first intercourse and age at response.
  
  
  METHODS
  A random selection of women aged 18-46 years living in Denmark, Norway and Sweden in 2011-2012, eligible for opportunistic or organized catch-up HPV vaccination.
  
  
  METHODS
  A total of 3805 women reported to have received the HPV vaccine and 40,247 reported not to have received it. Among vaccinees, 1539 received the HPV vaccine before or at the same age as sexual debut, of which 476 and 1063 were eligible for organized catch-up and opportunistic vaccination, respectively.
  
  
  METHODS
  Self-reported sexual behaviour, compared by hazard ratios and odds ratios for women who received the HPV vaccine before or at the same age as sexual debut versus women who did not receive the HPV vaccine.
  
  
  RESULTS
  HPV vaccination did not result in younger age at first intercourse. Women who received the HPV vaccine before or at the same age as sexual debut did not have more sexual partners than did non-vaccinees. Non-use of contraception during first intercourse was more common among non-vaccinees than among HPV vaccinees. The results were similar for organized catch-up and opportunistic vaccinees.
  
  
  CONCLUSIONS
  Women who received the HPV vaccine before or at the same age as sexual debut did not subsequently engage more in sexual risk taking behaviour than women who did not receive the HPV vaccine.
authors.affiliation: Department of Research, Cancer Registry of Norway, Oslo, Norway. Electronic address: bo.terning.hansen@kreftregisteret.no.
authors.forename: Bo T
authors.initials: BT
authors.lastname: Hansen
authors.affiliation: Unit of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark; Department of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. Electronic address: susanne@cancer.dk.
authors.forename: Susanne K
authors.initials: SK
authors.lastname: Kjær
authors.affiliation: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. Electronic address: lisen.arnheim.dahlstrom@ki.se.
authors.forename: Lisen
authors.initials: L
authors.lastname: Arnheim-Dahlström
authors.affiliation: Department of Epidemiology, Merck Research Laboratories, North Wales, USA. Electronic address: kaili_liaw@merck.com.
authors.forename: Kai-Li
authors.initials: KL
authors.lastname: Liaw
authors.affiliation: Unit of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark. Electronic address: kir@cancer.dk.
authors.forename: Kirsten E
authors.initials: KE
authors.lastname: Jensen
authors.affiliation: Unit of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark. Electronic address: ltt@cancer.dk.
authors.forename: Louise T
authors.initials: LT
authors.lastname: Thomsen
authors.affiliation: Unit of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark. Electronic address: munk@cancer.dk.
authors.forename: Christian
authors.initials: C
authors.lastname: Munk
authors.affiliation: Department of Research, Cancer Registry of Norway, Oslo, Norway. Electronic address: mari.nygard@kreftregisteret.no.
authors.forename: Mari
authors.initials: M
authors.lastname: Nygård
mesh_terms: D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D003718:Denmark; D005260:Female; D006801:Humans; D008875:Middle Aged; D009664:Norway; D016017:Odds Ratio; D030361:Papillomavirus Infections / Q000517:prevention & control; D053918:Papillomavirus Vaccines / Q000008:administration & dosage*; D016016:Proportional Hazards Models; D012309:Risk-Taking; D012725:Sexual Behavior / Q000706:statistics & numerical data*; D013548:Sweden; D014611:Vaccination / Q000706:statistics & numerical data*; D055815:Young Adult
chemical_list: D053918:Papillomavirus Vaccines
keywords: Adolescent health; Cervical cancer; First intercourse; HPV; Risk compensation; Sexual behaviour