title: Intra-aortic balloon pump treatment for patients with acute anterior wall myocardial infarction after reperfusion therapy.
abstract: We evaluated the effects of an intra-aortic balloon pump on hemodynamics, brain natriuretic peptide concentration and cardiac function of patients with acute myocardial infarction, after reperfusion therapy. Sixty-three patients with acute anterior wall ST-elevation myocardial infarction who underwent primary percutaneous coronary intervention were given an intra-aortic balloon pump (32 cases) or not (control group, 31 cases). The mean pulmonary arterial pressure, pulmonary capillary wedge pressure and cardiac index were measured with a Swan-Ganz catheter. The brain natriuretic peptide concentration was detected by immunochemiluminometric assay. Left ventricular end-diastolic diameter and left ventricular ejection fraction were measured by echocardiography. No difference in baseline was observed between the two groups on day 1 in the hospital. On day 5, mean pulmonary artery pressure and pulmonary capillary wedge pressure of patients with the intra-aortic balloon pump were significantly lower, and cardiac index of was higher than that of the controls, whereas no differences in left ventricular end-diastolic diameter or left ventricular ejection fraction were observed between the two groups. On days 5 and 90, the brain natriuretic peptide concentration of the intra-aortic balloon pump patients was lower than that of the controls. On day 90, left ventricular end-diastolic diameter was smaller in the intra-aortic balloon pump patients, but no difference in left ventricular ejection fraction was observed between the two groups. The intra-aortic balloon pump improved the hemodynamic index and cardiac function and decreased brain natriuretic peptide concentration in patients with acute anterior wall ST-elevation myocardial infarction.
authors.affiliation: Department of Cardiology, First Affiliated Hospital, Suzhou University, Suzhou, China.
authors.forename: C G
authors.initials: CG
authors.lastname: Feng
authors.affiliation: Department of Cardiology, First Affiliated Hospital, Suzhou University, Suzhou, China xiangjunyangcn@126.com.
authors.forename: X J
authors.initials: XJ
authors.lastname: Yang
authors.affiliation: Institute of Cardiovascular Disease of Xuzhou, Department of Cardiology, Xuzhou Central Hospital, Xuzhou, Jiangsu Province, China.
authors.forename: Q
authors.initials: Q
authors.lastname: Fu
authors.affiliation: Institute of Cardiovascular Disease of Xuzhou, Department of Cardiology, Xuzhou Central Hospital, Xuzhou, Jiangsu Province, China.
authors.forename: Y J
authors.initials: YJ
authors.lastname: Wang
authors.affiliation: Institute of Cardiovascular Disease of Xuzhou, Department of Cardiology, Xuzhou Central Hospital, Xuzhou, Jiangsu Province, China.
authors.forename: H Y
authors.initials: HY
authors.lastname: Ruan
authors.affiliation: Institute of Cardiovascular Disease of Xuzhou, Department of Cardiology, Xuzhou Central Hospital, Xuzhou, Jiangsu Province, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Lu
authors.affiliation: Institute of Cardiovascular Disease of Xuzhou, Department of Cardiology, Xuzhou Central Hospital, Xuzhou, Jiangsu Province, China.
authors.forename: X L
authors.initials: XL
authors.lastname: Li
authors.affiliation: Institute of Cardiovascular Disease of Xuzhou, Department of Cardiology, Xuzhou Central Hospital, Xuzhou, Jiangsu Province, China.
authors.forename: X P
authors.initials: XP
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D056988:Anterior Wall Myocardial Infarction / Q000503:physiopathology* / Q000601:surgery* / Q000628:therapy; D004452:Echocardiography; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007423:Intra-Aortic Balloon Pumping / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015425:Myocardial Reperfusion / Q000379:methods*; D020097:Natriuretic Peptide, Brain / Q000378:metabolism; D013318:Stroke Volume
chemical_list: D020097:Natriuretic Peptide, Brain