title: Simultaneous analysis of phthalates, adipate and polycyclic aromatic hydrocarbons in edible oils using isotope dilution-gas chromatography-mass spectrometry.
abstract: A method for simultaneous determination of 12 priority phthalates, adipate and polycyclic aromatic hydrocarbons (PAHs) in edible oils by isotope dilution-gas chromatography-mass spectrometry (ID-GC-MS) was developed for fast, accurate and trace analysis. The extraction and clean-up procedures were optimised, and using stable isotope-labelled internal standards for each analyte, relative standard deviations (RSDs) of 0.92-10.6% and spiked sample recoveries of 80.6-97.8% were obtained. Limits of detection for PAHs were in the range of 0.15-0.77 µg/kg and those for phthalates were in the range of 4.6-10.0 µg/kg. The calibration curves exhibited good linearities with regression coefficients of R(2) ≥ 0.99. Twelve edible oils were examined to evaluate the efficiency of this method. Among the 12 analytes, dibutyl phthalates (DBP), diethylhexyl phthalates (DEHP), diethylhexyl adipate (DEHA), benzo[a]anthracene (B[a]A), chrysene (Chry) and benzo[b]fluoranthene (B[b]F) were detected in the range of 1.17-806 µg/kg.
authors.affiliation: a Advanced Analysis Center, Korea Institute of Science and Technology , Seoul , Republic of Korea.
authors.forename: Min-Seok
authors.initials: MS
authors.lastname: Oh
authors.forename: Seon-Hwa
authors.initials: SH
authors.lastname: Lee
authors.forename: Myeong Hee
authors.initials: MH
authors.lastname: Moon
authors.forename: Dong Soo
authors.initials: DS
authors.lastname: Lee
authors.forename: Hyun-Mee
authors.initials: HM
authors.lastname: Park
mesh_terms: D000272:Adipates / Q000032:analysis*; D005506:Food Contamination / Q000032:analysis; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D007201:Indicator Dilution Techniques; D007554:Isotopes; D010795:Phthalic Acids / Q000032:analysis*; D010938:Plant Oils / Q000737:chemistry*; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D000272:Adipates; D007554:Isotopes; D010795:Phthalic Acids; D010938:Plant Oils; D011084:Polycyclic Aromatic Hydrocarbons; C032279:phthalic acid; C029900:adipic acid
keywords: GC–MS; adipate; edible oils; isotope dilution; phthalates; polycyclic aromatic hydrocarbons; simultaneous determination