title: Thin-slice T2 MRI imaging predicts vascular pathology in hemifacial spasm: a case-control study.
abstract: Hemifacial spasm (HFS) is a condition that may severely reduce patients' quality of life. We sought to determine the sensitivity and specificity of thin-slice T2 magnetic resonance imaging (MRI) for detecting vascular compression in HFS patients. Prospective information was collected on 28 patients with HFS who presented to our center between March 2011 and March 2012 with thin-slice T2 MR imaging. The sensitivity and specificity for differentiating patients from controls were calculated. Sensitivities were 78.6% and 92.9% for the blinded radiologists and 75% for the partially blinded neurosurgeon. Specificities were 42.9% and 28.6% for the blinded radiologists and 75% for the partially blinded neurosurgeon. Magnetic resonance imaging of the facial nerve can guide clinicians in selecting patients who are good surgical candidates. Thin-slice T2 MRI should be viewed as supportive rather than diagnostic.
authors.affiliation: Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
authors.forename: Raymond F
authors.initials: RF
authors.lastname: Sekula
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Frederickson
authors.forename: Barton F
authors.initials: BF
authors.lastname: Branstetter
authors.forename: James E
authors.initials: JE
authors.lastname: Oskin
authors.forename: Dale R
authors.initials: DR
authors.lastname: Stevens
authors.forename: Nathan T
authors.initials: NT
authors.lastname: Zwagerman
authors.forename: Ramesh
authors.initials: R
authors.lastname: Grandhi
authors.forename: Marion A
authors.initials: MA
authors.lastname: Hughes
mesh_terms: D016022:Case-Control Studies; D002561:Cerebrovascular Disorders / Q000209:etiology / Q000473:pathology; D005154:Facial Nerve / Q000473:pathology; D005260:Female; D019569:Hemifacial Spasm / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D061145:Microvascular Decompression Surgery / Q000379:methods; D055806:Microvessels / Q000473:pathology*; D008875:Middle Aged; D012680:Sensitivity and Specificity
keywords: MRI; botulinum toxin; facial nerve; hemifacial spasm; microvascular decompression