title: Valley fever: danger lurking in a dust cloud.
abstract: Coccidioides immitis and Coccidioides posadasii contribute to the development of Valley Fever. The ability of these fungal pathogens to evade the host immune system creates difficulty in recognition and treatment of this debilitating infection. In this review, we describe the current knowledge of Valley Fever and approaches to improve prevention, detection, and treatment.
authors.affiliation: Department of Molecular Cell Biology, University of California, Merced, CA 95343, USA; Health Sciences Research Institute, University of California, Merced, CA 95343, USA.
authors.forename: Larry
authors.initials: L
authors.lastname: Johnson
authors.affiliation: Health Sciences Research Institute, University of California, Merced, CA 95343, USA.
authors.forename: Erin M
authors.initials: EM
authors.lastname: Gaab
authors.affiliation: Department of Molecular Cell Biology, University of California, Merced, CA 95343, USA; Health Sciences Research Institute, University of California, Merced, CA 95343, USA.
authors.forename: Javier
authors.initials: J
authors.lastname: Sanchez
authors.affiliation: Department of Molecular Cell Biology, University of California, Merced, CA 95343, USA; Health Sciences Research Institute, University of California, Merced, CA 95343, USA.
authors.forename: Phuong Q
authors.initials: PQ
authors.lastname: Bui
authors.affiliation: Department of Molecular Cell Biology, University of California, Merced, CA 95343, USA; Health Sciences Research Institute, University of California, Merced, CA 95343, USA.
authors.forename: Clarissa J
authors.initials: CJ
authors.lastname: Nobile
authors.affiliation: Department of Molecular Cell Biology, University of California, Merced, CA 95343, USA; Health Sciences Research Institute, University of California, Merced, CA 95343, USA.
authors.forename: Katrina K
authors.initials: KK
authors.lastname: Hoyer
authors.affiliation: Department of Internal Medicine, University of California San Francisco - Fresno, Fresno, CA 93703, USA.
authors.forename: Michael W
authors.initials: MW
authors.lastname: Peterson
authors.affiliation: Department of Molecular Cell Biology, University of California, Merced, CA 95343, USA; Health Sciences Research Institute, University of California, Merced, CA 95343, USA. Electronic address: david.ojcius@gmail.com.
authors.forename: David M
authors.initials: DM
authors.lastname: Ojcius
mesh_terms: D003045:Coccidioides / Q000302:isolation & purification* / Q000472:pathogenicity; D003047:Coccidioidomycosis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology* / Q000517:prevention & control; D004391:Dust; D004783:Environmental Microbiology; D006801:Humans
chemical_list: D004391:Dust
keywords: Adaptive immunity; Coccidioides; Fungal pathogen; Innate immunity; Lung infection