title: Cyclosporine A as a Primary Treatment for Panniculitis-like T Cell Lymphoma: A Case with a Long-Term Remission.
abstract: Subcutaneous panniculitis-like T cell lymphoma (SPTL) is a distinctive cutaneous lymphoma characterized by an infiltration of subcutaneous tissue by neoplastic T cells, similar to panniculitis. It is well-established that patients who are diagnosed with SPTL usually respond poorly to chemotherapy, showing fatal outcome. As a first line treatment for SPTL, anthracycline-based chemotherapy was most frequently used. For the treatment of SPTL, the efficacy of cyclosporine A has been recently reported in relapsed SPTL after anthracycline-based chemotherapy. However, it is still not clear whether cyclosporine A can be used as a first-line treatment against SPTL. Here, we report a case of SPTL, which achieved complete remission for nine years after first-line cyclosporine A therapy. This study suggests that cyclosporine A can induce a complete long-term remission as a first-line treatment.
authors.affiliation: Departments of Internal Medicine, Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Korea.
authors.forename: Won Sup
authors.initials: WS
authors.lastname: Lee
authors.forename: Ji-Hyen
authors.initials: JH
authors.lastname: Hwang
authors.forename: Moon Jin
authors.initials: MJ
authors.lastname: Kim
authors.forename: Se-Il
authors.initials: SI
authors.lastname: Go
authors.forename: Anna
authors.initials: A
authors.lastname: Lee
authors.forename: Haa-Na
authors.initials: HN
authors.lastname: Song
authors.forename: Min Jeong
authors.initials: MJ
authors.lastname: Lee
authors.forename: Myung Hee
authors.initials: MH
authors.lastname: Kang
authors.forename: Hoon-Gu
authors.initials: HG
authors.lastname: Kim
authors.forename: Jeong-Hee
authors.initials: JH
authors.lastname: Lee