title: Helicobacter pylori infection and skin disorders.
abstract: Helicobacter pylori is a Gram-negative bacterium that has been linked to peptic ulcer disease, gastric lymphoma, and gastric carcinoma. Apart from its well-demonstrated role in gastroduodenal diseases, some authors have suggested a potential role of Helicobacter pylori infection in several extra-intestinal pathologies including haematological, cardiovascular, neurological, metabolic, autoimmune, and dermatological diseases. Some studies suggest an association between Helicobacter pylori infection and skin diseases such as chronic idiopathic urticaria and rosacea. There have also been few case reports documenting association between Helicobacter pylori and psoriasis vulgaris, Behçet's disease, alopecia areata, Henoch-Schönlein purpura, and Sweet's syndrome. However, more systematic studies are required to clarify the proposed association between Helicobacter pylori and skin diseases; most of the studies do not show relevant relationships of these diseases with Helicobacter pylori infections. This review discusses skin diseases that are believed to be associated with Helicobacter pylori.
authors.affiliation: Dermatology Department, Cerrahpasa Faculty of Medicine, Istanbul University, Cerrahpaşa, 34099 Istanbul, Turkey.
authors.forename: Zekayi
authors.initials: Z
authors.lastname: Kutlubay
authors.affiliation: Dermatology Department, Cerrahpasa Faculty of Medicine, Istanbul University, Cerrahpaşa, 34099 Istanbul, Turkey.
authors.forename: Tuba
authors.initials: T
authors.lastname: Zara
authors.affiliation: Dermatology Department, Cerrahpasa Faculty of Medicine, Istanbul University, Cerrahpaşa, 34099 Istanbul, Turkey.
authors.forename: Burhan
authors.initials: B
authors.lastname: Engin
authors.affiliation: Dermatology Department, Cerrahpasa Faculty of Medicine, Istanbul University, Cerrahpaşa, 34099 Istanbul, Turkey.
authors.forename: Server
authors.initials: S
authors.lastname: Serdaroğlu
authors.affiliation: Dermatology Department, Cerrahpasa Faculty of Medicine, Istanbul University, Cerrahpaşa, 34099 Istanbul, Turkey.
authors.forename: Yalçin
authors.initials: Y
authors.lastname: Tüzün
authors.affiliation: Blood Bank, Tissue Typing Laboratory, Cerrahpasa Faculty of Medicine, Istanbul University, Cerrahpaşa, 34099 Istanbul, Turkey.
authors.forename: Erkan
authors.initials: E
authors.lastname: Yilmaz
authors.affiliation: Council of Forensic Medicine of Turkey, Bursa Morgue Department, 16010, Bursa, Turkey.
authors.forename: Bülent
authors.initials: B
authors.lastname: Eren
mesh_terms: D016481:Helicobacter Infections / Q000503:physiopathology*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D012393:Rosacea / Q000382:microbiology; D012871:Skin Diseases / Q000382:microbiology* / Q000503:physiopathology*; D014581:Urticaria / Q000382:microbiology
keywords: Helicobacter pylori; Skin diseases; Urticaria