title: Fatigue and quality of life in women treated for various types of gynaecological cancers: a cross-sectional study.
abstract: OBJECTIVE
  To examine the prevalence of cancer-related fatigue in women treated for various types of gynaecological cancers and, for these cancers, to assess fatigue in relation to distress, health-related quality of life, demography and treatment characteristics.
  
  
  BACKGROUND
  Advances in treatment of cancer have improved the likelihood of survival. Consequently, there are a growing number of patients who become survivors after cancer and who face side effects even years after treatment. One of the most frequently reported side effects across all types and stages of the disease is cancer-related fatigue.
  
  
  METHODS
  A descriptive cross-sectional study.
  
  
  METHODS
  One hundred and twenty women treated for gynaecological cancers who were participants in an intervention study were included. Fatigue, psychological distress, health-related QoL and demographics were assessed by questionnaires. Disease and treatment characteristics were extracted from medical records.
  
  
  RESULTS
  Cancer-related fatigue was reported in 53% of the women treated for gynaecological cancers, with a higher proportion in the group of cervical cancer, followed by ovarian cancer. Younger participants reported fatigue more frequently than older participants. When adjusting for age, the type of cancer a woman experiences was shown to have little impact on her risk of experiencing fatigue. The participants with fatigue reported higher levels of anxiety and depression than participants without fatigue. There was a relationship between fatigue and quality of life as measured by SF-36 domains.
  
  
  CONCLUSIONS
  The findings underscore the importance of screening for fatigue, patient education and symptom management. This should be included in a standard procedure during treatment and follow-up. Both somatic and psychological aspects of fatigue should be emphasised.
  
  
  CONCLUSIONS
  The findings imply the need for health personnel to have focus on fatigue during the entire cancer trajectory of women after gynaecological cancers, as well as the need for screening, information, guidance and symptom management.
authors.affiliation: Department of Obstetrics and Gynaecology, Haukeland University Hospital, Bergen, Norway; Department of Clinical Science, University of Bergen, Bergen, Norway.
authors.forename: Ragnhild Johanne Tveit
authors.initials: RJ
authors.lastname: Sekse
authors.forename: Karl Ove
authors.initials: KO
authors.lastname: Hufthammer
authors.forename: Margrethe Elin
authors.initials: ME
authors.lastname: Vika
mesh_terms: D001007:Anxiety / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003863:Depression / Q000453:epidemiology; D005221:Fatigue / Q000453:epidemiology* / Q000523:psychology; D005260:Female; D005833:Genital Neoplasms, Female / Q000150:complications* / Q000523:psychology* / Q000628:therapy; D006801:Humans; D008875:Middle Aged; D015995:Prevalence; D011788:Quality of Life; D013315:Stress, Psychological / Q000453:epidemiology / Q000523:psychology*; D011795:Surveys and Questionnaires
keywords: anxiety; depression; fatigue; gynaecological cancers; quality of life