title: Comparative evaluation of clinical efficacy of β-tri calcium phosphate (Septodont-RTR)™ alone and in combination with platelet rich plasma for treatment of intrabony defects in chronic periodontitis.
abstract: OBJECTIVE
  To assess the clinical outcome by comparing β-tri calcium phosphate (Septodont RTR)™ along with platelet rich plasma (PRP) and β-tri calcium phosphate (β-TCP) alone in intrabony defects, by clinical evaluation in a 6-month analysis.
  
  
  METHODS
  Ten patients participated in the study. Using a split-mouth design, interproximal bony defects were surgically treated with either platelet rich plasma (PRP) combined with β-tri calcium phosphate (β-TCP) or β-TCP alone. Plaque Index (PI), Gingival Index, Probing Pocket Depth (PPD), Clinical Attachment Level (CAL) were recorded 6 months after surgery.
  
  
  RESULTS
  At 6 months after therapy, the PRP combined with β-TCP group showed mean PPD reduction of 2.50, CAL mean gain of 2.60 + 1.43. The β-TCP group showed mean PPD reduction of 2.80 mm, mean CAL gain of 2.60 mm. On intra-group comparison, there was greater PPD reduction and CAL gain at 6 months in both the groups. In intergroup comparison of PRP/β-TCP and β-TCP alone, there was no statistical significant difference observed. (P = 0.55, and 0.87 for PPD and CAL gain).
  
  
  CONCLUSIONS
  Both therapies resulted in significant PPD reduction, CAL gain. The present study shows that treatment of intrabony periodontal defects with combination of PRP and β-TCP does not have additional improvements when compared with β-TCP alone within 6 months follow-up.
authors.affiliation: Department of Periodontics, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India.
authors.forename: Jyostna
authors.initials: J
authors.lastname: Pinipe
authors.affiliation: Department of Periodontics, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India.
authors.forename: Narendra Babu
authors.initials: NB
authors.lastname: Mandalapu
authors.affiliation: Department of Periodontics, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India.
authors.forename: Sesha Reddy
authors.initials: SR
authors.lastname: Manchala
authors.affiliation: Department of Periodontics, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India.
authors.forename: Satheesh
authors.initials: S
authors.lastname: Mannem
authors.affiliation: Department of Periodontics, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India.
authors.forename: N V S Sruthima
authors.initials: NV
authors.lastname: Gottumukkala
authors.affiliation: Department of Periodontics, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India.
authors.forename: Suneetha
authors.initials: S
authors.lastname: Koneru
keywords: Infrabony defects; periodontal regeneration; platelet rich plasma; β-tri calcium phosphate