title: [Influence of reverse osmosis concentrate on physicochemical parameters of Sini decoction material system and their relevance].
abstract: OBJECTIVE
  By studying the process of reverse osmosis system for traditional Chinese medicine materials physicochemical parameters affecting the osmotic pressure of its relevance, new compound system reverse osmosis process design methods were explored.
  
  
  METHODS
  Three concentrations materials for high, middle and low were dubbed with Sini decoction as a model drug, and pretreated by 50 thousand relative molecular weight cut-off ultrafiltration membrane. The viscosity, turbidity, conductivity, salinity, TDS, pH value and osmotic pressure of each sample were determined after the reverse osmosis to study the physical and chemical parameters between their respective correlations with the osmotic pressure, and characterized by HPLC chromatograms showing changes before and after the main chemical composition of samples of reverse osmosis.
  
  
  RESULTS
  Conductivity-osmotic pressure, salinity-osmotic pressure of the linear correlation coefficient, TDS-osmotic pressure between the three sets of parameters were 0.963 8, 0.932 7, 0.973 7, respectively. Reverse osmosis concentrate and its characteristic spectrum ultrafiltrate HPLC similarity were up to 0. 968 or more, except the low concentrations.
  
  
  CONCLUSIONS
  There is a significant correlation between the three physicochemical parameters (conductivity, salinity, TDS) and osmotic pressure of each sample system, and there is also significant linear correlation between salinity, conductivity, TDS. The original chemical composition of Sini decoction material concentrate was completely remained after the process of reverse osmosis.
authors.forename: Tang-Hui
authors.initials: TH
authors.lastname: Jin
authors.forename: Liu-Hong
authors.initials: LH
authors.lastname: Zhang
authors.forename: Hua-Xu
authors.initials: HX
authors.lastname: Zhu
authors.forename: Li-Wei
authors.initials: LW
authors.lastname: Guo
authors.forename: Bo
authors.initials: B
authors.lastname: Li
authors.forename: Ming-Ming
authors.initials: MM
authors.lastname: Lu
mesh_terms: D055598:Chemical Phenomena; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D008970:Molecular Weight; D009997:Osmotic Pressure; D013499:Surface Properties; D014783:Viscosity
chemical_list: D004365:Drugs, Chinese Herbal; C478756:sini tang