title: Malignant fibrous histiocytoma of maxillary alveolar ridge extending to the hard palate.
abstract: Malignant fibrous histiocytoma (MFH) is the most common soft-tissue sarcoma occurring in adults. This entity was first described by O'Brian and Stout in 1964. Apart from the soft-tissues, this tumor has been reported to occur in all other parts of the body including bone. It has male predilection and is usually noticed in the fifth to seventh decades of life. It commonly affects extremities and retroperitoneum, whereas involvement of the head and neck region is comparatively rare. However, when the head and neck region is affected, the most common sites are the maxillary sinus and the nasal cavity, in which case, later involvement of the maxillary alveolar bone can happen. The oral cavity is a relatively less common site for MFH. This article describes clinical, computed tomographic and microscopic features of a MFH of the maxillary alveolar ridge extending to the hard palate in a 46-year-old female patient. Histogenesis, advanced imaging features, differential diagnosis, and management of MFH are also discussed.
authors.affiliation: Department of Oral Medicine and Radiology, Rural Dental College, Loni, India.
authors.forename: Vikrant O
authors.initials: VO
authors.lastname: Kasat
authors.forename: Harish
authors.initials: H
authors.lastname: Saluja
authors.forename: Bhimmapa M
authors.initials: BM
authors.lastname: Rudagi
authors.forename: Jitendra V
authors.initials: JV
authors.lastname: Kalburge
authors.forename: Shivani
authors.initials: S
authors.lastname: Sachdeva
mesh_terms: D005260:Female; D051677:Histiocytoma, Malignant Fibrous / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008437:Maxilla / Q000473:pathology / Q000601:surgery; D008441:Maxillary Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D021362:Palate, Hard / Q000473:pathology / Q000601:surgery; D011859:Radiography