title: From prednisone to pylori: a case of Helicobacter pylori-induced chronic immune thrombocytopenia.
abstract: A 54-year-old woman was seen by her primary care internist for a general health maintenance visit. Her major chronic illness was immune thrombocytopenic purpura (ITP) for which she had been treated with prednisone therapy for the past 15 years. Recent review of possible aetiologies of her chronic thrombocytopenia revealed infection with Helicobacter pylori. Successful eradication resulted in complete resolution of her thrombocytopenia within 2 months. She was weaned from steroid therapy and at 1-year follow-up, her platelet counts remained in the normal range. This case report summarises what is known about the association of H. pylori infection and ITP.
authors.affiliation: Mayo Medical School, Rochester, Minnesota, USA.
authors.forename: Larisa J N
authors.initials: LJ
authors.lastname: Hill
authors.affiliation: The Division of Primary Care Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
authors.forename: Ericka E
authors.initials: EE
authors.lastname: Tung
mesh_terms: D001792:Blood Platelets / Q000473:pathology; D002908:Chronic Disease; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D016481:Helicobacter Infections / Q000150:complications / Q000382:microbiology; D016480:Helicobacter pylori; D006801:Humans; D008875:Middle Aged; D010976:Platelet Count; D011241:Prednisone / Q000627:therapeutic use; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D013921:Thrombocytopenia / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology
chemical_list: D005938:Glucocorticoids; D011241:Prednisone