title: Pedicle-Screw-Based Dynamic Systems and Degenerative Lumbar Diseases: Biomechanical and Clinical Experiences of Dynamic Fusion with Isobar TTL.
abstract: Dynamic systems in the lumbar spine are believed to reduce main fusion drawbacks such as pseudarthrosis, bone rarefaction, and mechanical failure. Compared to fusion achieved with rigid constructs, biomechanical studies underlined some advantages of dynamic instrumentation including increased load sharing between the instrumentation and interbody bone graft and stresses reduction at bone-to-screw interface. These advantages may result in increased fusion rates, limitation of bone rarefaction, and reduction of mechanical complications with the ultimate objective to reduce reoperations rates. However published clinical evidence for dynamic systems remains limited. In addition to providing biomechanical evaluation of a pedicle-screw-based dynamic system, the present study offers a long-term (average 10.2 years) insight view of the clinical outcomes of 18 patients treated by fusion with dynamic systems for degenerative lumbar spine diseases. The findings outline significant and stable symptoms relief, absence of implant-related complications, no revision surgery, and few adjacent segment degenerative changes. In spite of sample limitations, this is the first long-term report of outcomes of dynamic fusion that opens an interesting perspective for clinical outcomes of dynamic systems that need to be explored at larger scale.
authors.affiliation: Department of Spine Surgery, University Neurological Hospital P Wertheimer and Hospices Civils de Lyon, University Claude Bernard Lyon 1, 69003 Lyon, France.
authors.forename: Cédric
authors.initials: C
authors.lastname: Barrey
authors.affiliation: Department of Spine Surgery, University Neurological Hospital P Wertheimer and Hospices Civils de Lyon, University Claude Bernard Lyon 1, 69003 Lyon, France.
authors.forename: Gilles
authors.initials: G
authors.lastname: Perrin
authors.affiliation: Department of Clinical Research, Alphatecspine, 62217 Beaurains, France.
authors.forename: Sabina
authors.initials: S
authors.lastname: Champain