title: [Iron and inflammation in renal diseases].
abstract: Subclinical inflammation is one of the key mechanisms responsible for the development and progression of chronic kidney disease. It may stem from uremia, ongoing inflammation in kidney as well as latent bacterial and viral infections. Inflammation also plays a significant role in the pathogenesis of anemia of chronic disease through its impact on the iron metabolism. The paper presents the current knowledge concerning the involvement of iron in the development of anemia in chronic kidney disease, with particular reference to the role of hepcidin in systemic iron circulation.
authors.forename: Ewelina
authors.initials: E
authors.lastname: Łukaszyk
authors.forename: Jolanta
authors.initials: J
authors.lastname: Małyszko
mesh_terms: D000740:Anemia / Q000209:etiology* / Q000378:metabolism*; D018450:Disease Progression; D064451:Hepcidins / Q000378:metabolism*; D006801:Humans; D007501:Iron / Q000378:metabolism*; D009393:Nephritis / Q000150:complications*; D051436:Renal Insufficiency, Chronic / Q000209:etiology* / Q000378:metabolism
chemical_list: D064451:Hepcidins; D007501:Iron