title: Effect of a carbohydrate-protein multi-ingredient supplement on intermittent sprint performance and muscle damage in recreational athletes.
abstract: Carbohydrate-protein-based multi-ingredient supplements have been proposed as an effective strategy for limiting the deleterious effects of exercise-induced muscle damage. This study compares the effects of a commercially available carbohydrate-protein supplement enriched with l-glutamine and l-carnitine-l-tartrate to carbohydrate alone or placebo on sprint performance, muscle damage markers, and recovery from intermittent exercise. On 3 occasions, 10 recreationally trained males ingested a multi-ingredient, a carbohydrate supplement, or a placebo before, during, and immediately after a 90-min intermittent repeated sprint test. Fifteen-metre sprint times, creatine kinase, myoglobin, and interleukin-6 were assessed before (pre), immediately after (post), 1 h after (1h), and 24 h after (24h) exercise. Total sprint time measured during the intermittent protocol was not different between conditions. Fifteen-metre sprint time was slower (p < 0.05) at post, 1h and 24h compared with pre without differences between conditions (p > 0.05). Creatine kinase at 24h was lower (p < 0.05) in the multi-ingredient (461.8 ± 271.8 U·L) compared with both carbohydrate and placebo (606 ± 314.5 U·L and 636 ± 344.6 U·L, respectively). Myoglobin increased (p < 0.05) in all 3 conditions at post and 1h compared with pre, showing lower values at 1h (p < 0.05) for the carbohydrate and a trend (p = 0.060) for multi-ingredient compared with the placebo condition (211.4 ± 127.2 ng·mL(-1) and 239.4 ± 103.8 ng·mL(-1) vs. 484.6 ± 200.0 ng·mL(-1), respectively). Interleukin-6 increased at both post and 1h compared with pre (p < 0.05) with no differences between conditions. In conclusion, ingesting a multi-ingredient supplement before, during, and immediately after a 90-min intermittent sprint test resulted in no effects on performance and fatigue while the accumulation of some biomarkers of muscle damage could be attenuated.
authors.affiliation: a Centre for Sport Science and Human Performance, School of Science, University of Greenwich, Medway Campus Central Avenue, Chatham Maritime, Kent ME4 4TB, UK.
authors.forename: Fernando
authors.initials: F
authors.lastname: Naclerio
authors.forename: Eneko
authors.initials: E
authors.lastname: Larumbe-Zabala
authors.forename: Robert
authors.initials: R
authors.lastname: Cooper
authors.forename: Alfonso
authors.initials: A
authors.lastname: Jimenez
authors.forename: Mark
authors.initials: M
authors.lastname: Goss-Sampson
mesh_terms: D000328:Adult; D054874:Athletic Performance / Q000502:physiology*; D004040:Dietary Carbohydrates / Q000008:administration & dosage*; D004044:Dietary Proteins / Q000008:administration & dosage*; D019587:Dietary Supplements; D004311:Double-Blind Method; D006801:Humans; D008297:Male; D018763:Muscle Fatigue; D009135:Muscular Diseases / Q000517:prevention & control*
chemical_list: D004040:Dietary Carbohydrates; D004044:Dietary Proteins
keywords: creatine kinase; créatine kinase; fatigue musculaire; interleukin-6; interleukine-6; muscle fatigue; myoglobin; myoglobine; nutritional supplements; supplément nutritif