title: Fever management in intensive care patients with infections.
abstract: With great interest we read the article by Dr Schoeneberg and colleagues regarding gender-specific differences with respect to outcome in patients with severe traumatic injury. The authors show that, apart from the acute phase after trauma, women have a more favorable trauma severity-adjusted outcome, with shorter ICU and hospital stay and lower sepsis rates. However, a possible mechanism of action behind this difference was not suggested. We hypothesize that, in view of the fact that morbidity and mortality in the post-acute phase after trauma are often caused by infectious complications, gender differences in immunity might explain the observed differences.
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Young
authors.forename: Manoj
authors.initials: M
authors.lastname: Saxena
mesh_terms: D000818:Animals; D003141:Communicable Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D003422:Critical Care / Q000379:methods* / Q000639:trends; D019468:Disease Management; D005334:Fever / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D006801:Humans; D007362:Intensive Care Units / Q000639:trends