title: All-organic microelectromechanical systems integrating specific molecular recognition--a new generation of chemical sensors.
abstract: Cantilever-type all-organic microelectromechanical systems based on molecularly imprinted polymers for specific analyte recognition are used as chemical sensors. They are produced by a simple spray-coating-shadow-masking process. Analyte binding to the cantilever generates a measurable change in its resonance frequency. This allows label-free detection by direct mass sensing of low-molecular-weight analytes at nanomolar concentrations.
authors.affiliation: Laboratoire de l'Intégration, du Matériau au Système UMR 5218, Université de Bordeaux, F-33405, Talence, France.
authors.forename: Cédric
authors.initials: C
authors.lastname: Ayela
authors.forename: Georges
authors.initials: G
authors.lastname: Dubourg
authors.forename: Claude
authors.initials: C
authors.lastname: Pellet
authors.forename: Karsten
authors.initials: K
authors.lastname: Haupt
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods; D004867:Equipment Design; D007536:Isomerism; D055617:Micro-Electrical-Mechanical Systems / Q000295:instrumentation* / Q000379:methods*; D055616:Microtechnology / Q000295:instrumentation / Q000379:methods; D011108:Polymers / Q000737:chemistry; D011433:Propranolol / Q000737:chemistry
chemical_list: D011108:Polymers; D011433:Propranolol
keywords: chemical sensors; microelectromechanical systems; microfabrication; molecularly imprinted polymers; organic materials