title: Trends in the Incidence and In-Hospital Outcomes of Elective Major Orthopaedic Surgery in Patients Eighty Years of Age and Older in the United States from 2000 to 2009.
abstract: BACKGROUND
  Although life expectancy continues to increase worldwide and advances occur in surgical techniques and medical treatment, the chronological age limit for patients to undergo elective major orthopaedic procedures remains a controversial subject. The purpose of this study was to examine the trends in the incidence and in-hospital outcomes of elective major orthopaedic surgery in patients eighty years of age and older in the United States as a whole.
  
  
  METHODS
  ICD-9-CM (International Classification of Diseases, 9th Revision, Clinical Modification) codes were used to identify patients at least eighty years of age in the Nationwide Inpatient Sample who underwent spinal fusion, total hip arthroplasty, or total knee arthroplasty from 2000 to 2009. Demographic data regarding the patient and health-care system were retrieved and analyzed.
  
  
  RESULTS
  From 2000 to 2009, there were increasing trends in the age-adjusted incidence of spinal fusion, total hip arthroplasty, and total knee arthroplasty in patients at least eighty years of age (rate per 100,000 per year, 40 to 102 for spinal fusion, 181 to 257 for total hip arthroplasty, and 300 to 477 for total knee arthroplasty; p ≤ 0.001 for each). The overall in-hospital complication rate remained stable over time for spinal fusion and total knee arthroplasty and increased for total hip arthroplasty (9.0% to 10.3%, p = 0.008). The in-hospital mortality rate decreased over time (1.1% to 0.6% for spinal fusion, 0.5% to 0.3% for total hip arthroplasty, and 0.3% to 0.2% for total knee arthroplasty; p < 0.05 for each). The overall in-hospital complication and mortality rates of patients at least eighty years of age were significantly higher than those of patients sixty-five to seventy-nine years of age (p < 0.001 for both).
  
  
  CONCLUSIONS
  During the previous decade, the rates of elective major orthopaedic surgical procedures in patients at least eighty years of age increased in the U.S. The in-hospital mortality rates decreased, whereas the overall in-hospital complication rates remained stable or increased. The overall event rates were low, and these elective procedures could be offered to very elderly patients.
  
  
  METHODS
  Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.
authors.affiliation: Department of Orthopaedic Surgery, NYU Hospital for Joint Diseases, 301 East 17th Street, New York, NY 10003. E-mail address: hiroyoshihara55@yahoo.co.jp.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yoshihara
authors.affiliation: Department of Statistical Science, School of Advanced Sciences, The Graduate University for Advanced Studies, 10-3 Midori-machi, Tachikawa, Tokyo 190-8562, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Yoneoka
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D017558:Elective Surgical Procedures / Q000706:statistics & numerical data*; D017052:Hospital Mortality; D006760:Hospitalization; D006801:Humans; D019637:Orthopedic Procedures / Q000706:statistics & numerical data*; D011183:Postoperative Complications / Q000453:epidemiology*; D013997:Time Factors; D016896:Treatment Outcome; D014481:United States