title: Pathogenesis and treatment of atherosclerosis in lupus.
abstract: The prevalence of atherosclerosis (ATH) is higher in patients with systemic lupus erythematosus (SLE) and occurs at an earlier age. The lupus-related factors that account for this increased risk are likely numerous and related to the factors described in this article. Identifying of at-risk subjects and increasing the understanding of pathogenesis of ATH in SLE is critical for improving the quality of care and improving mortality in this vulnerable population.
authors.affiliation: Division of Rheumatology, David Geffen School of Medicine, University of California, Los Angeles, 1000 Veteran Avenue, Room 32-59, Los Angeles, CA 90095, USA. Electronic address: mmcmahon@mednet.ucla.edu.
authors.forename: Maureen
authors.initials: M
authors.lastname: McMahon
authors.affiliation: Division of Rheumatology, David Geffen School of Medicine, University of California, Los Angeles, 1000 Veteran Avenue, Room 32-59, Los Angeles, CA 90095, USA.
authors.forename: Brian
authors.initials: B
authors.lastname: Skaggs
mesh_terms: D000367:Age Factors; D050197:Atherosclerosis / Q000150:complications / Q000453:epidemiology / Q000378:metabolism / Q000517:prevention & control; D015415:Biomarkers / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D016207:Cytokines / Q000378:metabolism*; D019468:Disease Management; D006801:Humans; D050356:Lipid Metabolism; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000453:epidemiology / Q000378:metabolism / Q000628:therapy; D017063:Outcome Assessment, Health Care; D015995:Prevalence; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors
chemical_list: D015415:Biomarkers; D016207:Cytokines
keywords: Atherosclerosis; Cardiovascular diseases; Cytokine; Proinflammatory lipids; Systemic lupus erythematosus