title: Synchronous tumors of the female genital tract: a 20-year experience in a single center.
abstract: OBJECTIVE
  To evaluate the clinicopathological characteristics and the clinical outcome of synchronous malignant neoplasms of the female reproductive tract.
  
  
  METHODS
  Patients who were operated and diagnosed with synchronous malignant tumor of the genital system (n = 25) at the Dokuz Eylul University Department of Obstetrics and Gynecology Gynecologic Oncology Unit between 1992 and 2012 were included into this study. Recurrent, metastatic and metachronously detected tumors were not included. Age at diagnosis, parity menopausal status, hormone use, presenting sign or symptoms and the clinical outcomes were evaluated.
  
  
  RESULTS
  20 of 25 patients had endometrial-ovarian cancer. The mean age at diagnosis was 53,6 years. The most common presenting symptom was abnormal uterine bleeding. The median follow-up duration for all patients was 69 months. Overall survival for all patients was 87 months and 81 months for patients with endometrial-ovarian cancer 5-year survival rate was 73% for all patients and 68% for patients with endometrial-ovarian cancer.
  
  
  CONCLUSIONS
  Endometrial-ovarian cancer togetherness is the most common in synchronous gynecologic malignancies. They occur at a younger age and have more favorable prognosis than metastatic primary gynecologic tumors.
authors.forename: Bahadir
authors.initials: B
authors.lastname: Saatli
authors.forename: Nuri
authors.initials: N
authors.lastname: Yildirim
authors.forename: Ali Cenk
authors.initials: AC
authors.lastname: Ozay
authors.forename: Meral
authors.initials: M
authors.lastname: Koyuncuoglu
authors.forename: Binnaz
authors.initials: B
authors.lastname: Demirkan
authors.forename: Uğur
authors.initials: U
authors.lastname: Saygili
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015984:Causality; D015897:Comorbidity; D016889:Endometrial Neoplasms / Q000401:mortality*; D005260:Female; D005833:Genital Neoplasms, Female / Q000401:mortality; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000401:mortality*; D010051:Ovarian Neoplasms / Q000401:mortality*; D015996:Survival Rate; D014592:Uterine Hemorrhage / Q000453:epidemiology; D014594:Uterine Neoplasms / Q000401:mortality*