title: Inappropriate antidiuretic hormone secretion due to squamous cell lung cancer.
abstract: The syndrome of inappropriate secretion of antidiuretic hormone is a disorder of impaired water excretion caused by the inability to suppress secretion of antidiuretic hormone. It has been commonly associated with small cell carcinoma. The association of this syndrome with squamous cell lung carcinoma has rarely been reported, with only 4 cases over the past two decades in the English literature. We describe the case of a 75-year-old Caucasian male who developed the syndrome after a right pneumonectomy for down-staged squamous cell lung cancer previously treated with neoadjuvant platinum-based chemotherapy and radiotherapy.
authors.affiliation: Cardiothoracic Surgery and Cardiology Departments, Iaso General Hospital, Athens, Greece info@kotoulas.com.
authors.forename: Christophoros
authors.initials: C
authors.lastname: Kotoulas
authors.affiliation: Cardiothoracic Surgery and Cardiology Departments, Iaso General Hospital, Athens, Greece.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Panagiotou
authors.affiliation: Cardiothoracic Surgery and Cardiology Departments, Iaso General Hospital, Athens, Greece.
authors.forename: Panteleimon
authors.initials: P
authors.lastname: Tsipas
authors.affiliation: Cardiothoracic Surgery and Cardiology Departments, Iaso General Hospital, Athens, Greece.
authors.forename: Emmanouil
authors.initials: E
authors.lastname: Koutoulakis
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000097:blood / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D059248:Chemoradiotherapy / Q000379:methods; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000097:blood / Q000209:etiology*; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D010257:Paraneoplastic Syndromes / Q000097:blood / Q000209:etiology*; D011013:Pneumonectomy / Q000379:methods; D014667:Vasopressins / Q000097:blood
chemical_list: D014667:Vasopressins
keywords: Carcinoma; hyponatremia; inappropriate ADH syndrome; lung neoplasms; non-small-cell lung; pneumonectomy; vasopressins