title: Electronic readout enzyme-linked immunosorbent assay with organic field-effect transistors as a preeclampsia prognostic.
abstract: Organic field-effect transistor (OFET) sensors can meet the need for portable and real-time diagnostics. An electronicreadout enzyme-linked immunosorbent assay using OFETs for the detection of a panel of three biomarkers in complex media to create a pre-eclampsia prognostic is demonstrated, along with biodetection utilizing a fully inkjet-printed and flexible OFET to underscore our ability to produce disposable devices.
authors.affiliation: Department of Chemical Engineering, Stanford University, Stanford, CA, 94305.
authors.forename: Mallory L
authors.initials: ML
authors.lastname: Hammock
authors.forename: Oren
authors.initials: O
authors.lastname: Knopfmacher
authors.forename: Tse Nga
authors.initials: TN
authors.lastname: Ng
authors.forename: Jeffrey B-H
authors.initials: JB
authors.lastname: Tok
authors.forename: Zhenan
authors.initials: Z
authors.lastname: Bao
mesh_terms: D000906:Antibodies / Q000276:immunology; D015415:Biomarkers / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay; D004800:Enzymes, Immobilized / Q000737:chemistry / Q000378:metabolism; D005260:Female; D005949:Glucose Oxidase / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D011225:Pre-Eclampsia / Q000175:diagnosis* / Q000378:metabolism; D011247:Pregnancy; D011379:Prognosis; D014173:Transistors, Electronic; D040281:Vascular Endothelial Growth Factor Receptor-1 / Q000097:blood / Q000276:immunology
chemical_list: D000906:Antibodies; D015415:Biomarkers; D004800:Enzymes, Immobilized; D005949:Glucose Oxidase; D040281:Vascular Endothelial Growth Factor Receptor-1
keywords: biodetection; organic field-effect transistors; preeclampsia; serum