title: Relationship between quality of life and nurse-led bedside symptom evaluations in patients with chemotherapy-induced peripheral neuropathy.
abstract: OBJECTIVE
  This cross-sectional study aimed at determining the relationship between patient-reported quality of life (QOL) and nurse-led bedside evaluations of chemotherapy-induced peripheral neuropathy symptoms.
  
  
  METHODS
  One hundred ninety-five patients treated at the oncology clinic at our institution were assessed using Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity and nurse-led bedside examinations. The relationship between self-reported QOL and bedside examinations was evaluated using Spearman rank correlations.
  
  
  RESULTS
  Scores of upper and lower extremity muscle strength based on the bedside examinations showed a weak negative correlation with the emotional well-being subscale of Functional Assessment of Cancer Therapy-General. Further, weak negative relationships were present between QOL and the following nurse-reported parameters: vibration perception in the hand, upper extremity muscle strength, touch and vibration perception in the feet, and tendon reflexes.
  
  
  CONCLUSIONS
  Collectively, our results indicate that nurse-led bedside evaluation is a noninvasive and useful method for detecting neurotoxicity and evaluating the patient's QOL both during and after treatment.
authors.affiliation: College of Nursing, The Catholic University, Seoul, South Korea.
authors.forename: Yang-Sook
authors.initials: YS
authors.lastname: Yoo
authors.affiliation: College of Nursing, Jeju National University, Jeju, South Korea. Electronic address: ohcho@jejunu.ac.kr.
authors.forename: Ok-Hee
authors.initials: OH
authors.lastname: Cho
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects; D001291:Attitude of Health Personnel; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy; D020258:Neurotoxicity Syndromes / Q000175:diagnosis* / Q000209:etiology; D009726:Nurses / Q000523:psychology*; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced / Q000175:diagnosis*; D017671:Platinum Compounds / Q000009:adverse effects; D011788:Quality of Life; D011795:Surveys and Questionnaires; D063189:Symptom Assessment / Q000379:methods / Q000592:standards*; D043823:Taxoids / Q000009:adverse effects
chemical_list: D000970:Antineoplastic Agents; D017671:Platinum Compounds; D043823:Taxoids
keywords: neurotoxicity syndromes; quality of life; symptom assessment