title: Hypothermia in hypoxic ischemic encephalopathy: a 5-year experience at Phoenix Children's Hospital Neuro NICU.
abstract: We found TH to be safe and effective in improving survival and neurodevelopmental outcomes following HIE in term children. Additionally, the use of a multidisciplinary team involved with these complex patients and the use of advanced monitoring techniques will likely assist in identifying second insults (ie, seizures), leading to more rapidly instituted treatments. Our study, however, had the limitation of including only retrospective data from patients in whom TH was provided. This makes it difficult to identify the specific sources for the improved outcomes and/or the presence of complications.
authors.affiliation: Barrow Neurological Institute at Phoenix Children's Hospital, 1919 East Thomas Road, Phoenix, AZ 85016, USA.
authors.forename: Jorge I
authors.initials: JI
authors.lastname: Arango
authors.affiliation: Barrow Neurological Institute at Phoenix Children's Hospital, 1919 East Thomas Road, Phoenix, AZ 85016, USA.
authors.forename: Kimberlee
authors.initials: K
authors.lastname: Allred
authors.affiliation: Barrow Neurological Institute at Phoenix Children's Hospital, 1919 East Thomas Road, Phoenix, AZ 85016, USA.
authors.forename: P David
authors.initials: PD
authors.lastname: Adelson
authors.affiliation: Barrow Neurological Institute at Phoenix Children's Hospital, 1919 East Thomas Road, Phoenix, AZ 85016, USA.
authors.forename: Parita
authors.initials: P
authors.lastname: Soni
authors.affiliation: Barrow Neurological Institute at Phoenix Children's Hospital, 1919 East Thomas Road, Phoenix, AZ 85016, USA.
authors.forename: Ryan
authors.initials: R
authors.lastname: Stradleigh
authors.affiliation: Barrow Neurological Institute at Phoenix Children's Hospital, 1919 East Thomas Road, Phoenix, AZ 85016, USA.
authors.forename: Remy
authors.initials: R
authors.lastname: Wahnoun
authors.affiliation: Barrow Neurological Institute at Phoenix Children's Hospital, 1919 East Thomas Road, Phoenix, AZ 85016, USA. Electronic address: ccperelman@me.com.
authors.forename: Cristina
authors.initials: C
authors.lastname: Carballo
mesh_terms: D002648:Child; D006776:Hospitals, Pediatric; D006801:Humans; D007036:Hypothermia, Induced / Q000379:methods*; D020925:Hypoxia-Ischemia, Brain / Q000628:therapy*; D007363:Intensive Care Units, Neonatal; D016896:Treatment Outcome
keywords: Hypoxic ischemic encephalopathy; NICU; Neurodevelopmental; Therapeutic hypothermia