title: Hematoma volume as the major determinant of outcomes after intracerebral hemorrhage.
abstract: Intracerebral hemorrhage (ICH) is a leading cause of morbidity and mortality, greatly linked to hematoma volume. Understanding the characteristics and size of hematoma is integral to evaluating severity and prognosis after ICH. Examination of the literature suggests that markers for hematoma size vary, but the key range between 20-30 mL is most widely used as the cut-off for classification of hematoma volume. The role of hematoma volume in episodes of hematoma expansion and re-bleeding further impact outcomes, with increased growth associated with larger hematoma volume. Additionally, many commonly used predictors of ICH outcomes are directly related to hematoma volume, implicating it as an important variable when determining outcomes. In conclusion, hematoma volume is likely the most significant determinant of outcomes in intracerebral hemorrhage.
authors.affiliation: Cerebrovascular Laboratory, Department of Neurosurgery Columbia University Medical Centre, 630 West 168th Street, New York, NY, United States. Electronic address: mal653@nyumc.org.
authors.forename: Melissa A
authors.initials: MA
authors.lastname: LoPresti
authors.affiliation: Cerebrovascular Laboratory, Department of Neurosurgery Columbia University Medical Centre, 630 West 168th Street, New York, NY, United States.
authors.forename: Samuel S
authors.initials: SS
authors.lastname: Bruce
authors.affiliation: Cerebrovascular Laboratory, Department of Neurosurgery Columbia University Medical Centre, 630 West 168th Street, New York, NY, United States.
authors.forename: Elvis
authors.initials: E
authors.lastname: Camacho
authors.affiliation: Cerebrovascular Laboratory, Department of Neurosurgery Columbia University Medical Centre, 630 West 168th Street, New York, NY, United States.
authors.forename: Sudkir
authors.initials: S
authors.lastname: Kunchala
authors.affiliation: Cerebrovascular Laboratory, Department of Neurosurgery Columbia University Medical Centre, 630 West 168th Street, New York, NY, United States.
authors.forename: Byron G
authors.initials: BG
authors.lastname: Dubois
authors.affiliation: Cerebrovascular Laboratory, Department of Neurosurgery Columbia University Medical Centre, 630 West 168th Street, New York, NY, United States.
authors.forename: Eliza
authors.initials: E
authors.lastname: Bruce
authors.affiliation: Cerebrovascular Laboratory, Department of Neurosurgery Columbia University Medical Centre, 630 West 168th Street, New York, NY, United States.
authors.forename: Geoff
authors.initials: G
authors.lastname: Appelboom
authors.affiliation: Cerebrovascular Laboratory, Department of Neurosurgery Columbia University Medical Centre, 630 West 168th Street, New York, NY, United States.
authors.forename: E Sander
authors.initials: ES
authors.lastname: Connolly
mesh_terms: D002543:Cerebral Hemorrhage / Q000150:complications* / Q000175:diagnosis*; D006406:Hematoma / Q000209:etiology* / Q000473:pathology*; D006801:Humans; D011237:Predictive Value of Tests
keywords: Hematoma expansion; Hematoma volume; Intracerebral hemorrhage; Outcomes; Predictors; Stroke