title: Construction of collagen gel scaffolds for mechanical stress analysis.
abstract: We designed a cyclic compression system using readily available six-well culture plates to investigate the influence of mechanical stress on skin-like structures. The effects of cyclic mechanical stress on protein expression by cells were easily examined, and hence, this system should be useful for further analysis of skin responses to mechanical stress.
authors.affiliation: a Advanced Technology Research Laboratory , NOF Corporation , Ibaraki , Japan.
authors.forename: Masao
authors.initials: M
authors.lastname: Hara
authors.forename: Masahiro
authors.initials: M
authors.lastname: Nakashima
authors.forename: Takahiro
authors.initials: T
authors.lastname: Fujii
authors.forename: Kazuki
authors.initials: K
authors.lastname: Uehara
authors.forename: Chisako
authors.initials: C
authors.lastname: Yokono
authors.forename: Ron
authors.initials: R
authors.lastname: Hashizume
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Nomura
mesh_terms: D018929:Cell Culture Techniques; D003094:Collagen / Q000737:chemistry*; D005347:Fibroblasts / Q000166:cytology; D005782:Gels / Q000737:chemistry*; D006801:Humans; D012867:Skin / Q000166:cytology; D013314:Stress, Mechanical
chemical_list: D005782:Gels; D003094:Collagen
keywords: collagen gel; fibroblast; mechanical compression; skin model