title: Effects of aerobic exercise during hemodialysis on physical functional performance and depression.
abstract: Previous studies have concluded that exercise training is beneficial to patients on hemodialysis (HD). Results, however, have shown that differences in the type, intensity, and frequency of physical exercise lead to variability in its effects on physical functional performance and depression. Further research is thus warranted. Our aim was to evaluate the effects of aerobic exercise on physical functional performance and depression during HD. Using a pretest-posttest control group design, we recruited HD patients and nonrandomly assigned them to an exercise group (n = 13) that completed a 12-week aerobic exercise program during HD or a control group (n = 11) that did no exercise during HD. The primary outcome measures were physical functional performance, as evaluated by the 6-min walk test and the sit-to-stand test, and depression, as evaluated by the Beck Depression Inventory II. The secondary outcome measures were albumin and triglyceride levels and hematocrit. Results revealed significant between-group differences in physical functional performance and depression but not in albumin level, hematocrit, or triglyceride level. Findings suggest that exercise may play a critical role in physical functional performance and may decrease depression. Exercise should be encouraged and performed during HD in HD centers.
authors.affiliation: School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan, Republic of China Hemodialysis Center, Cardinal Tien Hospital, New Taipei City, Taiwan, Republic of China.
authors.forename: Yueh-Min
authors.initials: YM
authors.lastname: Liu
authors.affiliation: School of Nursing, Yuanpei University, Hsinchu City, Taiwan, Republic of China.
authors.forename: Yu-Chu
authors.initials: YC
authors.lastname: Chung
authors.affiliation: Kaohsiung Medical University, Kaohsuing City, Taiwan, Republic of China.
authors.forename: Jung-San
authors.initials: JS
authors.lastname: Chang
authors.affiliation: School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan, Republic of China meiling@ntunhs.edu.tw.
authors.forename: Mei-Ling
authors.initials: ML
authors.lastname: Yeh
mesh_terms: D000328:Adult; D003863:Depression / Q000517:prevention & control*; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D009043:Motor Activity / Q000502:physiology*; D006435:Renal Dialysis
keywords: aerobic exercise; albumin; and triglyceride level; depression; hematocrit; hemodialysis; physical function performance