title: An atypical meningioma demystified and advanced magnetic resonance imaging techniques.
abstract: A 40-year-old male presented with visuospatial processing disturbances. Family history was free. Conventional and advanced magnetic resonance imaging (MRI) studies were performed. On T2 and fluid attenuation inversion recovery images, an increased signal intensity extra-axial lesion was demonstrated. Post-contrast scans depicted homogeneous intense contrast medium enhancement. T2* star sequence was negative for hemorrhagic or calcification foci. Diffusion-weighted imaging findings were indicative of malignant behavior and magnetic resonance venography confirmed superior sagittal sinus infiltration. Increased cerebral blood volume values were observed and peri-lesional oedema on perfusion-weighted imaging was also demonstrated. The signal intensity-time curve depicted the characteristic meningioma pattern. Spectroscopy showed increased choline and alanine levels, but decreased N-acetyl-aspartate levels. Conventional MRI is adequate for typical types of meningiomas. However, the more atypical ones, in which even the histopathologic specimen may demonstrate characteristics of typical meningioma, could be easier diagnosed with advanced MRI techniques.
authors.forename: Despoina
authors.initials: D
authors.lastname: Voultsinou
authors.affiliation: Department of Neuroradiology, University Hospital of Zürich, Zürich, Switzerland.
authors.forename: Georgios K
authors.initials: GK
authors.lastname: Matis
authors.forename: Olga I
authors.initials: OI
authors.lastname: Chrysou
authors.forename: Theodossios A
authors.initials: TA
authors.lastname: Birbilis
authors.forename: Angeliki
authors.initials: A
authors.lastname: Cheva
authors.forename: Triantafillos
authors.initials: T
authors.lastname: Geroukis
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008579:Meningioma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D009361:Neoplasm Invasiveness