title: Designing multi-branched gold nanoechinus for NIR light activated dual modal photodynamic and photothermal therapy in the second biological window.
abstract: Gold nanoechinus can sensitize the formation of singlet oxygen in the first and the second near-infra red (NIR) biological windows and exert in vivo dual modal photodynamic and photothermal therapeutic effects (PDT and PTT) to destruct the tumors completely. This is the first literature example of the destruction of tumors in NIR window II induced by dual modal nanomaterial-mediated photodynamic and photothermal therapy (NmPDT & NmPTT).
authors.affiliation: Department of Chemistry, National Tsing Hua University, Hsinchu, 30013, Taiwan, ROC.
authors.forename: Priya
authors.initials: P
authors.lastname: Vijayaraghavan
authors.forename: Cheng-Hong
authors.initials: CH
authors.lastname: Liu
authors.forename: Raviraj
authors.initials: R
authors.lastname: Vankayala
authors.forename: Chi-Shiun
authors.initials: CS
authors.lastname: Chiang
authors.forename: Kuo Chu
authors.initials: KC
authors.lastname: Hwang
mesh_terms: D000818:Animals; D015195:Drug Design; D006046:Gold / Q000737:chemistry* / Q000494:pharmacology*; D007259:Infrared Rays; D008546:Melanoma, Experimental / Q000188:drug therapy; D051379:Mice; D049329:Nanostructures; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000737:chemistry / Q000494:pharmacology
chemical_list: D017319:Photosensitizing Agents; D006046:Gold
keywords: biological window; gold nanoechinus; photodynamic therapy; photothermal therapy; singlet oxygen