title: Role of exercise training on autonomic changes and inflammatory profile induced by myocardial infarction.
abstract: The cardiovascular autonomic imbalance in patients after myocardial infarction (MI) provides a significant increase in mortality rate, and seems to precede metabolic, hormonal, and immunological changes. Moreover, the reduction in the parasympathetic function has been associated with inflammatory response in different pathological conditions. Over the years, most of the studies have indicated the exercise training (ET) as an important nonpharmacological tool in the management of autonomic dysfunction and reduction in inflammatory profile after a myocardial infarction. In this work, we reviewed the effects of ET on autonomic imbalance after MI, and its consequences, particularly, in the post-MI inflammatory profile. Clinical and experimental evidence regarding relationship between alterations in autonomic regulation and local or systemic inflammation response after MI were also discussed.
authors.affiliation: Human Movement Laboratory, Sao Judas Tadeu University (USJT), Avenida Taquari 546, 03166-000 São Paulo, SP, Brazil.
authors.forename: Bruno
authors.initials: B
authors.lastname: Rodrigues
authors.affiliation: Immunometabolism Research Group, Department of Physical Education, Universidade Estadual Paulista (UNESP), Rua Roberto Simonsen 305, 19060-900 Presidente Prudente, SP, Brazil.
authors.forename: Fabio S
authors.initials: FS
authors.lastname: Lira
authors.affiliation: Hypertension Unit, Heart Institute (InCor), Medical School of University of São Paulo, Avenida Dr. Enéas de Carvalho Aguiar 44, 05403-900 São Paulo, SP, Brazil.
authors.forename: Fernanda M
authors.initials: FM
authors.lastname: Consolim-Colombo
authors.affiliation: Hypertension Unit, Heart Institute (InCor), Medical School of University of São Paulo, Avenida Dr. Enéas de Carvalho Aguiar 44, 05403-900 São Paulo, SP, Brazil.
authors.forename: Juraci A
authors.initials: JA
authors.lastname: Rocha
authors.affiliation: Human Movement Laboratory, Sao Judas Tadeu University (USJT), Avenida Taquari 546, 03166-000 São Paulo, SP, Brazil.
authors.forename: Erico C
authors.initials: EC
authors.lastname: Caperuto
authors.affiliation: Translational Physiology Laboratory, Universidade Nove de Julho (UNINOVE), Rua Vergueiro 235/249, Liberdade, 01504-001 São Paulo, SP, Brazil.
authors.forename: Kátia
authors.initials: K
authors.lastname: De Angelis
authors.affiliation: Hypertension Unit, Heart Institute (InCor), Medical School of University of São Paulo, Avenida Dr. Enéas de Carvalho Aguiar 44, 05403-900 São Paulo, SP, Brazil.
authors.forename: Maria-Cláudia
authors.initials: MC
authors.lastname: Irigoyen
mesh_terms: D017776:Autonomic Pathways / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D006801:Humans; D009203:Myocardial Infarction / Q000378:metabolism* / Q000503:physiopathology*