title: Fresh extraction socket: spontaneous healing vs. immediate implant placement.
abstract: OBJECTIVE
  To evaluate the impact that immediate implant placement may have on bone remodelling in comparison with adjacent sockets left to heal spontaneously.
  
  
  METHODS
  In a beagle dog model (N = 16 dogs), mandibular premolars were extracted, and implants were placed in each distal socket (test) with the corresponding mesial site left to heal undisturbed (control). Healing was assessed measuring both the vertical distance between buccal and lingual crest (B'L') and the width of buccal and lingual walls at different levels. Five healing periods were evaluated. Differences between means for each variable and for each healing period between test and control were compared (Kruskal-Wallis test; Friedman test).
  
  
  RESULTS
  At 2 and 8 weeks of healing, the B'L' distance revealed significant higher values at test compared to control sites, being this difference three times higher at the end of the study (P < 0.05). In the test group, the width of the crest was reduced between baseline (0.37 [0.04]) and 8 weeks healing (0.13 [0.64]), demonstrating a 62% reduction of the initial width. These differences were not observed in the control group.
  
  
  CONCLUSIONS
  Immediate implant placement into fresh extraction sockets may jeopardize the vertical bone remodelling of the socket. Furthermore, a tendency towards greater buccal horizontal resorption was observed in the most coronal aspect of the buccal bone crest.
authors.affiliation: Postgraduate Periodontology, University Complutense of Madrid, Madrid, Spain.
authors.forename: Nicola
authors.initials: N
authors.lastname: Discepoli
authors.affiliation: Postgraduate Periodontology, University Complutense of Madrid, Madrid, Spain.
authors.forename: Fabio
authors.initials: F
authors.lastname: Vignoletti
authors.affiliation: Department of Oral Surgery, Universita' Federico II, Naples, Italy.
authors.forename: Luigi
authors.initials: L
authors.lastname: Laino
authors.affiliation: Postgraduate Periodontology, Universita degli Studi di Siena, Siena, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: de Sanctis
authors.affiliation: School of Veterinary Sciences of the University of Santiago de Compostela, Lugo, Spain.
authors.forename: Fernando
authors.initials: F
authors.lastname: Muñoz
authors.affiliation: Postgraduate Periodontology, University Complutense of Madrid, Madrid, Spain.
authors.forename: Mariano
authors.initials: M
authors.lastname: Sanz
mesh_terms: D032761:Animal Experimentation; D000818:Animals; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D004285:Dogs; D020390:Tooth Socket
chemical_list: D015921:Dental Implants
keywords: animal experiments; bone implant interactions; wound healing