title: Does pain mediate or moderate the effect of cognitive impairment on aggression in nursing home residents with dementia?
abstract: OBJECTIVE
  The purpose of this study was to investigate if pain mediates or moderates the relationship between cognitive impairment and aggressive behaviors in nursing home residents with dementia based on the Need-driven Dementia-compromised Behavior model.
  
  
  METHODS
  This was a secondary analysis of the Minimum Data Set assessment data on long-term care from the state of Florida during calendar year 2009. The data used in this study was the first comprehensive assessment data from residents with dementia (N = 56,577) in Medicare-certified or Medicaid-certified nursing homes. Path analysis using a series of hierarchical regression analyses and two-way analysis of variance was used to evaluate the mediating and moderating effect of pain on the relationship between the level of cognitive impairment and aggression.
  
  
  RESULTS
  Results indicated that pain did not mediate the relationship between cognition and aggressive behaviors, but there was evidence of a significant moderating effect of pain only for residents with severe cognitive impairment. Only among the residents with severe cognitive impairment, those with pain had significantly more frequent aggressive behaviors than those without pain.
  
  
  CONCLUSIONS
  A change in the frequency of aggressive behaviors in severely cognitively impaired residents should signal the possibility that the person is experiencing pain. Accurate but simple pain assessment in this population including these behavioral changes should be developed further, and pain should be well controlled to reduce these problematic behaviors.
authors.affiliation: Department of Adult and Elderly Nursing, College of Nursing, University of Florida, Gainesville, USA. Electronic address: hcahn@ufl.edu.
authors.forename: Hyochol
authors.initials: H
authors.lastname: Ahn
authors.affiliation: Department of Adult and Elderly Nursing, College of Nursing, University of Florida, Gainesville, USA.
authors.forename: Ann
authors.initials: A
authors.lastname: Horgas
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000374:Aggression; D003072:Cognition Disorders / Q000150:complications* / Q000523:psychology; D003704:Dementia / Q000150:complications* / Q000523:psychology; D005260:Female; D005431:Florida; D006801:Humans; D008134:Long-Term Care; D008297:Male; D009735:Nursing Homes; D010146:Pain / Q000150:complications* / Q000523:psychology; D010147:Pain Measurement / Q000379:methods; D057566:Self Report; D012919:Social Behavior
keywords: aggression; cognitive impairment; dementia; nursing homes; pain