title: [Factorial analysis of root canal irrigants and cements on coronal microleakage after cementing metal post-cores].
abstract: OBJECTIVE
  To evaluate the effect of different root canal irrigants and cements on coronal microleakage and the interaction effects after cementing metal post-cores.
  
  
  METHODS
  Ninety newly extracted single-rooted mandibular human premolars were endodontically treated. Post spaces were prepared in the root canals, and Co-Cr post-cores were cast routinely. The specimens were randomly divided into six groups (n = 15) via a two-way factorial design method. The irrigant factors (A) included A1: no irrigant (75% alcohol wiping), A2: 3% H2O2 + 0.9% NaCl, and A3: 15% ethylenediamine tetraacetic acid (EDTA) + 5.25% NaClO. The cement factors (B) included B1: zinc polycarboxylate cement, and B2: glass ionomer cement. The specimens received treatments based on the grouping of A1B1, A1B2, A2B1, A2B2, A3B1, and A3B2. All samples were sectioned longitudinally after being immersed in India ink for three weeks. The microleakages were observed using a stereomicroscope. The SPSS 13.0 software package was used for factorial analysis.
  
  
  RESULTS
  The mean microleakage scores and standard deviations were as follows: Group A1BI: (1,192.59 +/- 417.84) microm, Group A1B2: (1,317.38 +/- 527.35) microm, Group A2B1: (1,429.33 +/- 482.68) microm, Group A2B2: (1,026.79 +/- 459.49) microm, Group A3B1: (1,448.29 +/- 561.02) microm, and Group A3B2: (1,922.47 +/- 678.86) microm. The A2B2 group showed minimum microleakage, whereas the A3B2 group showed maximum microleakage. The microleakage degrees among different irrigants presented significant statistical difference (P < 0.05), but the two cements showed no significant difference (P > 0.05). An interactive effect on the microleakage existed between the irrigants and the cements after cementing the metal post-cores (P < 0.05).
  
  
  CONCLUSIONS
  When cementing metal post-cores, the coronal microleakage following 3% H2O2 + 0.9% NaCl irrigation combined with glass ionomer cement can be reduced. The combined application of 15% EDTA + 5.25% NaClO and glass ionomer cement significantly aggravates microleakage.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Zheng
authors.forename: Cuiling
authors.initials: C
authors.lastname: Liu
authors.forename: Jing
authors.initials: J
authors.lastname: Lan
authors.forename: Xu
authors.initials: X
authors.lastname: Gao
mesh_terms: D002484:Cementation; D003738:Dental Cements; D003763:Dental Leakage; D005899:Glass Ionomer Cements; D006801:Humans; D006861:Hydrogen Peroxide; D008670:Metals; D011176:Post and Core Technique; D019279:Resin Cements; D012388:Root Canal Irrigants
chemical_list: D003738:Dental Cements; D005899:Glass Ionomer Cements; D008670:Metals; D019279:Resin Cements; D012388:Root Canal Irrigants; D006861:Hydrogen Peroxide