title: Disseminated infection due to Mycobacterium bovis after intravesical BCG instillation.
abstract: Intravesical bacillus Calmette-Guerin (BCG) instillation has been adopted for the treatment of patients with superficial bladder cancer. Severe adverse events due to local instillation of BCG are uncommon, with an overall rate of serious complications of less than 5%. We report the case of an immunocompetent adult patient with multi-system effects, namely pneumonitis, granulomatous hepatitis and meningitis, who responded well to standard treatment for Mycobacterium bovis. This case highlights the importance of a thorough assessment of this type of patient.
authors.affiliation: Sara Marquez-Batalla, Esther Fraile-Villarejo, Servicio de Medicina Interna (CAUSA), IBSAL, Universidad de Salamanca, 37007 Salamanca, Spain.
authors.forename: Sara
authors.initials: S
authors.lastname: Marquez-Batalla
authors.affiliation: Sara Marquez-Batalla, Esther Fraile-Villarejo, Servicio de Medicina Interna (CAUSA), IBSAL, Universidad de Salamanca, 37007 Salamanca, Spain.
authors.forename: Esther
authors.initials: E
authors.lastname: Fraile-Villarejo
authors.affiliation: Sara Marquez-Batalla, Esther Fraile-Villarejo, Servicio de Medicina Interna (CAUSA), IBSAL, Universidad de Salamanca, 37007 Salamanca, Spain.
authors.forename: Moncef
authors.initials: M
authors.lastname: Belhassen-García
authors.affiliation: Sara Marquez-Batalla, Esther Fraile-Villarejo, Servicio de Medicina Interna (CAUSA), IBSAL, Universidad de Salamanca, 37007 Salamanca, Spain.
authors.forename: Nieves
authors.initials: N
authors.lastname: Gutierrez-Zubiaurre
authors.affiliation: Sara Marquez-Batalla, Esther Fraile-Villarejo, Servicio de Medicina Interna (CAUSA), IBSAL, Universidad de Salamanca, 37007 Salamanca, Spain.
authors.forename: Miguel
authors.initials: M
authors.lastname: Cordero-Sánchez
keywords: Bacillus Calmette-Guerin; Bladder cancer; Mycobacterium bovis; Tuberculosis