title: Mechanism of unpinning spirals by a series of stimuli.
abstract: Antitachycardia pacing (ATP) is widely used to terminate tachycardia before it proceeds to lethal fibrillation. The important prerequisite for successful ATP is unpinning of the spirals anchored to the obstacle by a series of stimuli. Here, to understand the mechanism of unpinning spirals by ATP, we propose a theoretical explanation based on a nonlinear eikonal relation and a kinematical model. The theoretical results are quantitatively consistent with the numerical simulations in both weak and high excitabilities.
authors.affiliation: Zhejiang Institute of Modern Physics and Department of Physics, Zhejiang University, Hangzhou 310027, China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Gao
authors.affiliation: Zhejiang Institute of Modern Physics and Department of Physics, Zhejiang University, Hangzhou 310027, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Zhang
mesh_terms: D001696:Biomechanical Phenomena; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D003198:Computer Simulation; D008955:Models, Cardiovascular; D017711:Nonlinear Dynamics