title: Clinical effectiveness of non-invasive selective cryolipolysis.
abstract: BACKGROUND
  Excess subcutaneous fat causes not only cosmetic issues, but also substantial systemic health problems. Cryolipolysis has been reported to provide non-invasive fat reduction that significantly reduces subcutaneous fat cells with controlled, localized cooling.
  
  
  OBJECTIVE
  This study is intended to determine whether a cryolipolysis device can effectively reduce subcutaneous fat without damaging the overlying skin or causing significant side effects and ultimately produce improved cosmetic results.
  
  
  METHODS
  A total of 15 patients participated in this study and they were treated unilaterally in a split-body trial manner with a non-invasive cryolipolysis device (Micool(™), Hironic Co., Seongnam, Korea). The degree of improvement was assessed by both objective and subjective assessments. Complications and side effects were recorded at every visit.
  
  
  RESULTS
  The results of both objective and subjective assessments showed significant improvements in subcutaneous fat reduction without any meaningful complications.
  
  
  CONCLUSIONS
  Non-invasive selective cryolipolysis has been reported to be a safe and effective treatment modality for the reduction of excess adipose tissue. Therefore, cryolipolysis is a promising technology that could be an appropriate and safe therapeutic option for subcutaneous fat reduction.
authors.affiliation: Dr. Kim's Skin & Laser Clinic, Dermatology , Suwon , Republic of Korea.
authors.forename: Jiehoon
authors.initials: J
authors.lastname: Kim
authors.forename: Dai Hyun
authors.initials: DH
authors.lastname: Kim
authors.forename: Hwa Jung
authors.initials: HJ
authors.lastname: Ryu
mesh_terms: D000328:Adult; D017679:Cryotherapy / Q000379:methods*; D005260:Female; D006801:Humans; D015187:Lipectomy / Q000379:methods*; D008297:Male; D017060:Patient Satisfaction; D056910:Republic of Korea; D050151:Subcutaneous Fat / Q000601:surgery*
keywords: cryolipolysis; fat removal