title: Pulmonary arterial hypertension in pregnancy.
abstract: Pulmonary hypertension is a medical condition characterized by elevated pulmonary arterial pressure and secondary right heart failure. Pulmonary arterial hypertension is a subset of pulmonary hypertension, which is characterized by an underlying disorder of the pulmonary arterial vasculature. Pulmonary hypertension can also occur secondarily to structural cardiac disease, autoimmune disorders, and toxic exposures. Although pregnancies affected by pulmonary hypertension and pulmonary arterial hypertension are rare, the pathophysiology exacerbated by pregnancy confers both high maternal and fetal mortality and morbidity. In light of new treatment modalities and the use of a multidisciplinary approach to care, maternal outcomes may be improving.
authors.affiliation: Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, 622 W 168th St, PH 16-66, New York, NY 10032. Electronic address: sgo2105@columbia.edu.
authors.forename: Sarah G
authors.initials: SG
authors.lastname: Običan
authors.affiliation: Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, 622 W 168th St, PH 16-66, New York, NY 10032.
authors.forename: Kirsten L
authors.initials: KL
authors.lastname: Cleary
mesh_terms: D000773:Anesthesia, Obstetrical / Q000379:methods*; D000077300:Bosentan; D002243:Carbolines; D037001:Directive Counseling; D011464:Epoprostenol; D015199:Extracorporeal Membrane Oxygenation / Q000379:methods*; D065627:Familial Primary Pulmonary Hypertension / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006801:Humans; D016285:Iloprost; D007231:Infant, Newborn; D010879:Piperazines; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000503:physiopathology / Q000628:therapy*; D011256:Pregnancy Outcome; D018566:Pregnancy, High-Risk; D011379:Prognosis; D011652:Pulmonary Circulation; D011687:Purines; D000068677:Sildenafil Citrate; D013449:Sulfonamides; D000068581:Tadalafil
chemical_list: D002243:Carbolines; D010879:Piperazines; D011687:Purines; D013449:Sulfonamides; D000068581:Tadalafil; D000068677:Sildenafil Citrate; D011464:Epoprostenol; D016285:Iloprost; D000077300:Bosentan
keywords: Eisenmenger’s syndrome; pregnancy; pulmonary arterial hypertension in pregnancy; pulmonary hypertension