title: [Apelin activity in patients with essential hypertension nd accompanied prediabetes and type 2 diabetes mellitus].
abstract: Studying of apelin's activity corresponding to pronunciation of carbohydrate disorders was provided in 136 patients with essential hypertension. General clinical and laboratory investigations were used. In (34,46%) patients with essential hypertension comorbid type 2 diabetes was revealed, in 37 (31,92%) patients - pre diabetes. Significant increasing of apelin levels were estimated in the whole group of hypertensive patients with marked expression in patients with comorbid type 2 diabetes. Significant correlations of apelin with components of carbohydrate pool dedicate that apelin takes part in the development of gluco-metabolic disorders in essential hypertension.
authors.forename: A V
authors.initials: AV
authors.lastname: Demidenko
mesh_terms: D000328:Adult; D000368:Aged; D000073861:Apelin; D050260:Carbohydrate Metabolism; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications / Q000473:pathology; D000075222:Essential Hypertension; D005260:Female; D005947:Glucose / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000150:complications / Q000473:pathology; D036341:Intercellular Signaling Peptides and Proteins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011236:Prediabetic State / Q000097:blood* / Q000150:complications / Q000473:pathology
chemical_list: C115436:APLN protein, human; D000073861:Apelin; D036341:Intercellular Signaling Peptides and Proteins; D005947:Glucose