title: Brain: positron emission tomography tracers beyond [¹⁸F]fluorodeoxyglucose.
abstract: Several PET radiopharmaceuticals beyond FDG have been used to study the physiology and pathophysiology in neurosciences. This article provides a broad overview of some of the commonly studied radiopharmaceuticals for PET imaging in selected neurologic conditions, particularly attempting to study their clinical relevance. Future studies on the use of advanced PET imaging in delineating neural pathophysiology, drug development, and altering patient management and outcomes across the disciplines of neurosciences are needed.
authors.affiliation: Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
authors.forename: Tarun
authors.initials: T
authors.lastname: Singhal
authors.affiliation: Division of Nuclear Medicine, Department of Radiology, University of Pennsylvania School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: Abass
authors.initials: A
authors.lastname: Alavi
authors.affiliation: Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. Electronic address: ckkim@bwh.harvard.edu.
authors.forename: Chun K
authors.initials: CK
authors.lastname: Kim
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging*; D002250:Carbon Radioisotopes; D003704:Dementia / Q000000981:diagnostic imaging*; D004827:Epilepsy / Q000000981:diagnostic imaging*; D005462:Fluorine Radioisotopes; D006801:Humans; D009069:Movement Disorders / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals
chemical_list: D002250:Carbon Radioisotopes; D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals
keywords: Brain; Central nervous system; Dementia; Epilepsy; Neuroinflammation; Parkinson disease; Positron; Positron emission tomography