title: [Obesity and cancer: «Dangerous friendship»].
abstract: Obesity and cancer are one of the most important health problems is Spain. Between 23 and 28% of the adult population in Spain are obese, 39% are overweight and 36% have abdominal obesity. The association between obesity and type 2 diabetes mellitus, hypertension, dyslipidemia and sleep obstructive apnea is well known. On the contrary, the association between obesity and cancer is less known, because the recent evidence on it. Several prospective studies have shown during the last years the strong relationship between obesity and cancer of colon, breast in post-menopausal women, endometrial, kidney and pancreas as well as esophageal adenocarcinoma. Furthermore there is recent evidence showing that liver, gallbladder, thyroid and ovarian cancer as well as leukemia, multiple myeloma and Hodgkin lymphomas are probably associated with obesity, yet more studies are needed. A better knowledge of the relation between cancer and obesity will allow improving the prevention strategies against cancer, a more efficient early detection, and a more suitable treatment of obesity and overweight. Although the mechanisms of carcinogenesis of obesity are not well established, avoiding overweight and obesity are considered one of the best approaches to reduce the risk of cancer. Therefore the general population must be aware that cancer is one of the most important hazards associated with the current obesity epidemic in our society.
authors.affiliation: Unidad de Nutrición, Ambiente y Cáncer, Instituto Catalán de Oncología (ICO), L'Hospitalet de Llobregat, Barcelona, España. Electronic address: cagonzalez@iconcologia.net.
authors.forename: Carlos A
authors.initials: CA
authors.lastname: González Svatetz
authors.affiliation: Servicio de Endocrinología y Nutrición, Hospital del Mar, Departament de Medicina, Universitat Autónoma de Barcelona, Barcelona, España; Centros de Investigación Biomédica en Red (CIBER) Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, España.
authors.forename: Alberto
authors.initials: A
authors.lastname: Goday Arnó
mesh_terms: D000328:Adult; D002277:Carcinoma / Q000453:epidemiology / Q000209:etiology; D015984:Causality; D015897:Comorbidity; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology; D004067:Digestive System Neoplasms / Q000453:epidemiology / Q000209:etiology; D004198:Disease Susceptibility; D055088:Early Detection of Cancer; D005260:Female; D005833:Genital Neoplasms, Female / Q000453:epidemiology / Q000209:etiology; D019337:Hematologic Neoplasms / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D008297:Male; D009017:Morbidity / Q000639:trends; D009369:Neoplasms / Q000453:epidemiology* / Q000209:etiology; D009765:Obesity / Q000453:epidemiology* / Q000503:physiopathology; D009928:Organ Specificity; D015995:Prevalence; D011446:Prospective Studies; D040242:Risk Reduction Behavior; D013030:Spain / Q000453:epidemiology; D013964:Thyroid Neoplasms / Q000453:epidemiology / Q000209:etiology
keywords: Abdominal obesity; Cancer; Cáncer; Obesidad; Obesidad abdominal; Obesity; Obesity prevalence; Overweight; Prevalencia obesidad; Sobrepeso