title: A Case of mild idiopathic adulthood ductopenia and brief review of literature.
abstract: Mild idiopathic adulthood ductopenia (IAD) is a rare cholestatic disease of unknown cause and characterized by interlobular bile duct loss in less than 50% of the portal tracts. We describe the case of a middLe-aged male who presented with persistent elevation of transaminases and alkaline phosphatase. He had a normal biliary tree on endoscopic retrograde cholangiopathy and negative anti-mitochondrial antibody. His liver biopsy specimen showed chronic biliary disease, duct loss in 4 out of 15 portal tracts and prominent cholestasis. Based on the work-up, he likely had mild IAD. Liver transplantation would be necessary if his disease becomes progressive.
authors.affiliation: Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA, Center for Liver Disease and Transplantation, Cedars-Sinai Medical Center, Los Angeles, CA, USA and Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, USA aung.kaung@cshs.org.
authors.forename: Aung
authors.initials: A
authors.lastname: Kaung
authors.affiliation: Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA, Center for Liver Disease and Transplantation, Cedars-Sinai Medical Center, Los Angeles, CA, USA and Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
authors.forename: Vinay
authors.initials: V
authors.lastname: Sundaram
authors.affiliation: Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA, Center for Liver Disease and Transplantation, Cedars-Sinai Medical Center, Los Angeles, CA, USA and Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
authors.forename: Deepti
authors.initials: D
authors.lastname: Dhall
authors.affiliation: Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA, Center for Liver Disease and Transplantation, Cedars-Sinai Medical Center, Los Angeles, CA, USA and Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
authors.forename: Tram T
authors.initials: TT
authors.lastname: Tran
keywords: idiopathic adulthood ductopenia; idiopathic cholestasis; primary biliary cirrhosis; small-duct primary sclerosing cholangitis