title: Fasting plasma glucose to avoid a full OGTT in the diagnosis of gestational diabetes.
abstract: OBJECTIVE
  To evaluate the performance of fasting plasma glucose (FPG) in determining the need for a full oral glucose tolerance test (OGTT) to diagnose gestational diabetes (GDM) by the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria.
  
  
  METHODS
  A multicenter cohort study of 4926 pregnant women 20 years or older consecutively enrolled in prenatal care clinics of the Brazilian National Health Service from 1991 to 1995. All women underwent a single 2 h 75 g OGTT by weeks 24-28 of pregnancy and were followed to detect adverse pregnancy outcomes.
  
  
  RESULTS
  A FPG cut-off value of 80 mg/dl indicated that only 38.7% of all women needed to undergo a complete OGTT, while detecting 96.9% of all GDM cases. When the 85 mg/dl cut-off was used, the corresponding percentages were 18.7% and 92.5%, respectively. The fraction of women labeled with GDM who had adverse pregnancy outcomes was nearly identical when using FPG strategies and universal full testing.
  
  
  CONCLUSIONS
  Using a FPG cut-off to diagnose GDM and to determine the need for post-load OGTT measurements is a valid strategy to diagnose GDM by IADPSG criteria. This approach may improve feasibility of applying IADPSG diagnostic criteria by reducing costs and increasing convenience.
authors.affiliation: Post Graduate Studies Program in Epidemiology, School of Medicine, Rio Grande do Sul Federal University, Rua Ramiro Barcelos 2600, sala 414, 90035-003, Porto Alegre, RS, Brazil. Electronic address: njtrujill@gmail.com.
authors.forename: J
authors.initials: J
authors.lastname: Trujillo
authors.affiliation: Post Graduate Studies Program in Epidemiology, School of Medicine, Rio Grande do Sul Federal University, Rua Ramiro Barcelos 2600, sala 414, 90035-003, Porto Alegre, RS, Brazil.
authors.forename: A
authors.initials: A
authors.lastname: Vigo
authors.affiliation: Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
authors.forename: A
authors.initials: A
authors.lastname: Reichelt
authors.affiliation: Post Graduate Studies Program in Epidemiology, School of Medicine, Rio Grande do Sul Federal University, Rua Ramiro Barcelos 2600, sala 414, 90035-003, Porto Alegre, RS, Brazil.
authors.forename: B B
authors.initials: BB
authors.lastname: Duncan
authors.affiliation: Post Graduate Studies Program in Epidemiology, School of Medicine, Rio Grande do Sul Federal University, Rua Ramiro Barcelos 2600, sala 414, 90035-003, Porto Alegre, RS, Brazil.
authors.forename: M I
authors.initials: MI
authors.lastname: Schmidt
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis*; D001938:Brazil; D015331:Cohort Studies; D016640:Diabetes, Gestational / Q000097:blood / Q000175:diagnosis*; D005215:Fasting / Q000097:blood*; D005260:Female; D005951:Glucose Tolerance Test / Q000706:statistics & numerical data*; D006801:Humans; D011247:Pregnancy; D012680:Sensitivity and Specificity
chemical_list: D001786:Blood Glucose
keywords: Diagnosis; Fasting plasma glucose; Gestational diabetes