title: Evaluation of different obesity indices as predictors of type 2 diabetes mellitus in a Chinese population.
abstract: BACKGROUND
  The aim of the present study was to compare correlation coefficients between anthropometric indices and blood glucose level, and to determine optimal cutoff points of obesity indices in a Chinese population.
  
  
  METHODS
  2419 males and 5140 females participated in this study in Changchun city. Weight, height, WC (waist circumference) and hip circumference were measured; and BMI (body mass index), WHtR (waist height ratio), WHR (waist hip ratio) and BAI (body adiposity index) were calculated by formulas. FPG (fasting plasma glucose), PPG (post-load plasma glucose), HbA1c (glycosylated hemoglobin) and FSI (fasting serum insulin) were measured.
  
  
  RESULTS
  WHtR had the highest partial correlation coefficients with blood glucose and HbA1c in both males and females; however, BAI had the lowest coefficients. AUC (area under receiver operating characteristic curves) for WHtR in screening type 2 diabetes mellitus were higher than other indices. We confirmed that the optimal cutoff points of obesity for WHtR, WHR, WC, BMI and BAI were 0.55, 0.92, 88.1, 25.9 and 28.1 in males, and 0.52, 0.85, 81.6, 24.6 and 31.0 in females, respectively.
  
  
  CONCLUSIONS
  Central obesity correlates more closely to glucose metabolism in Chinese population than general obesity. WHtR is the best index to predict type 2 diabetes mellitus in Chinese adults.
authors.affiliation: Department of Endocrinology and Metabolism, the First Hospital of Jilin University, Changchun, Jilin, China.
authors.forename: Xianchao
authors.initials: X
authors.lastname: Xiao
authors.forename: Yujia
authors.initials: Y
authors.lastname: Liu
authors.forename: Chenglin
authors.initials: C
authors.lastname: Sun
authors.forename: Xiaokun
authors.initials: X
authors.lastname: Gang
authors.forename: Jie
authors.initials: J
authors.lastname: Cheng
authors.forename: Suyan
authors.initials: S
authors.lastname: Tian
authors.forename: Ying
authors.initials: Y
authors.lastname: Gao
authors.forename: You
authors.initials: Y
authors.lastname: Lv
authors.forename: Zhonghua
authors.initials: Z
authors.lastname: Sun
authors.forename: Yazhen
authors.initials: Y
authors.lastname: Li
authors.forename: Ping
authors.initials: P
authors.lastname: He
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.forename: Gang
authors.initials: G
authors.lastname: Wang
authors.forename: Yuan
authors.initials: Y
authors.lastname: Gao
authors.forename: Liwen
authors.initials: L
authors.lastname: Zhu
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
authors.forename: Guixia
authors.initials: G
authors.lastname: Wang
mesh_terms: D050154:Adiposity; D000328:Adult; D001786:Blood Glucose; D001794:Blood Pressure; D001827:Body Height; D015992:Body Mass Index; D002681:China / Q000453:epidemiology; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D012372:ROC Curve; D012307:Risk Factors; D055105:Waist Circumference; D065927:Waist-Height Ratio; D049629:Waist-Hip Ratio
chemical_list: D001786:Blood Glucose
keywords: diabetes mellitus; obesity; receiver operating characteristic curve; type 2; 关键词：2型糖尿病，肥胖，受试者工作特征曲线。