title: Inflammatory and perfusion markers as risk factors and predictors of critically ill patient readmission.
abstract: OBJECTIVE
  To assess the performance of central venous oxygen saturation, lactate, base deficit, and C-reactive protein levels and SOFA and SWIFT scores on the day of discharge from the intensive care unit as predictors of patient readmission to the intensive care unit.
  
  
  METHODS
  This prospective and observational study collected data from 1,360 patients who were admitted consecutively to a clinical-surgical intensive care unit from August 2011 to August 2012. The clinical characteristics and laboratory data of readmitted and non-readmitted patients after discharge from the intensive care unit were compared. Using a multivariate analysis, the risk factors independently associated with readmission were identified.
  
  
  RESULTS
  The C-reactive protein, central venous oxygen saturation, base deficit, and lactate levels and the SWIFT and SOFA scores did not correlate with the readmission of critically ill patients. Increased age and contact isolation because of multidrug-resistant organisms were identified as risk factors that were independently associated with readmission in this study group.
  
  
  CONCLUSIONS
  Inflammatory and perfusion parameters were not associated with patient readmission. Increased age and contact isolation because of multidrug-resistant organisms were identified as predictors of readmission to the intensive care unit.
authors.affiliation: Departamento de Terapia Intensiva, Hospital Nossa Senhora da Conceição, Porto Alegre, RS, Brasil.
authors.forename: Moreno Calcagnotto dos
authors.initials: MC
authors.lastname: Santos
authors.affiliation: Departamento de Terapia Intensiva, Hospital Nossa Senhora da Conceição, Porto Alegre, RS, Brasil.
authors.forename: Márcio Manozzo
authors.initials: MM
authors.lastname: Boniatti
authors.affiliation: Departamento de Terapia Intensiva, Hospital Nossa Senhora da Conceição, Porto Alegre, RS, Brasil.
authors.forename: Carla Silva
authors.initials: CS
authors.lastname: Lincho
authors.affiliation: Departamento de Terapia Intensiva, Hospital Nossa Senhora da Conceição, Porto Alegre, RS, Brasil.
authors.forename: José Augusto Santos
authors.initials: JA
authors.lastname: Pellegrini
authors.affiliation: Departamento de Terapia Intensiva, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
authors.forename: Josi
authors.initials: J
authors.lastname: Vidart
authors.affiliation: Departamento de Terapia Intensiva, Hospital Nossa Senhora da Conceição, Porto Alegre, RS, Brasil.
authors.forename: Edison Moraes
authors.initials: EM
authors.lastname: Rodrigues Filho
authors.affiliation: Departamento de Terapia Intensiva, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
authors.forename: Silvia Regina Rios
authors.initials: SR
authors.lastname: Vieira
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000378:metabolism; D002097:C-Reactive Protein / Q000378:metabolism*; D016638:Critical Illness; D005260:Female; D006801:Humans; D007249:Inflammation / Q000473:pathology*; D007362:Intensive Care Units; D019344:Lactic Acid / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010100:Oxygen / Q000097:blood*; D010356:Patient Isolation / Q000706:statistics & numerical data; D010359:Patient Readmission / Q000706:statistics & numerical data*; D011446:Prospective Studies; D012307:Risk Factors; D055815:Young Adult
chemical_list: D015415:Biomarkers; D019344:Lactic Acid; D002097:C-Reactive Protein; D010100:Oxygen