title: Hypoglossal canal invasion by glomus jugulare tumors: clinico-radiological correlation.
abstract: The aim of this retrospective study is to assess the rate at which glomus jugulare tumors invade the hypoglossal canal (HC) and to correlate computed tomography (CT) and magnetic resonance imaging (MRI) findings with the clinical evidence of cranial nerve (CN) XII dysfunction. CT and MRI imaging modalities of 31 patients were blindly reviewed by an attending neuroradiologist. Imaging studies identified involvement in 22 tumors (22/31, 71.0%). Thirteen of 22 patients (59.1%) had clinically evident CN XII symptoms. Accuracy rate was 76.7% (23/30) for MRI and 78.6% (11/14) for CT. MRI showed 100% sensitivity but had only 59% specificity and the specificity for CT was 66.7%. When radiologists elucidate HC involvement, it may alter the surgical approach and may lead to more focused/accurate clinical evaluation of tongue function.
authors.affiliation: Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Medical Institution, 600 N. Wolfe Street, Baltimore, MD 21287. Electronic address: gursoymerve@yahoo.com.
authors.forename: Merve
authors.initials: M
authors.lastname: Gursoy
authors.affiliation: Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Medical Institution, 600 N. Wolfe Street, Baltimore, MD 21287.
authors.forename: Emanuele
authors.initials: E
authors.lastname: Orru
authors.affiliation: Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Medical Institution, 600 N. Wolfe Street, Baltimore, MD 21287.
authors.forename: Ari M
authors.initials: AM
authors.lastname: Blitz
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, The Johns Hopkins Medical Institution, 600 N. Wolfe Street, Baltimore, MD 21287.
authors.forename: John P
authors.initials: JP
authors.lastname: Carey
authors.affiliation: Department of Neurosurgery, The Johns Hopkins Medical Institution, 600 N. Wolfe Street, Baltimore, MD 21287.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Olivi
authors.affiliation: Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Medical Institution, 600 N. Wolfe Street, Baltimore, MD 21287.
authors.forename: David M
authors.initials: DM
authors.lastname: Yousem
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005925:Glomus Jugulare Tumor / Q000150:complications / Q000175:diagnosis*; D006258:Head and Neck Neoplasms / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007002:Hypoglossal Nerve / Q000000981:diagnostic imaging / Q000473:pathology*; D020437:Hypoglossal Nerve Diseases / Q000175:diagnosis* / Q000209:etiology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*
keywords: Computed tomography; Glomus jugulare; Hypoglossal canal; Magnetic resonance imaging