title: Clinical and histological evaluation of socket grafting using different types of bone substitute in adult patients.
abstract: OBJECTIVE
  This clinical and histological study evaluated the healing of extraction sockets after implantation of a biphasic calcium sulfate (CS) alone or in combination with a gamma-radiated human mineralized allograft.
  
  
  METHODS
  Ten healthy adult patients participated in the study. A minimum of 2 teeth, per patient, extracted for different reasons were evaluated. Each socket was randomly filled to the crest with either (a) a biphasic CS or (b) large particulate gamma-radiated human mineralized allograft in combination with a biphasic CS.
  
  
  RESULTS
  No complications during reentry of the socket site during bone core retrieval, such as inflammation/immunogenic response, were observed. Histological findings showed a mean new bone (NB) of 33% for sockets filled with biphasic CS and 31% for sockets filled with biphasic CS in combination with allograft material. There was no statistically significant difference in the percentage of NB and the presence of soft tissue between graft materials.
  
  
  CONCLUSIONS
  Biphasic CS used alone or in combination with an allograft resulted in the same amount of NB formation in alveolar ridge preservation procedures.
authors.affiliation: *Professor and Director of Graduate Periodontics, Department of Periodontics, School of Dentistry, Pontificia Universidad Católica Madre y Maestra (PUCMM), Santo Domingo, Dominican Republic. †Resident, Department of Periodontology, Graduate School, Catholic University of Santo Domingo, Santo Domingo, Dominican Republic. ‡Professor and Director, Department of Prosthodontics, Graduate School, Catholic University of Santo Domingo, Santo Domingo, Dominican Republic. §Assistant Professor, Department of Biomaterials and Biomimetics, New York University College of Dentistry, New York, NY. ‖Undergraduate Student, New York University College of Dentistry, New York, NY. ¶Associate Professor, Department of Biomaterials and Biomimetics, New York University College of Dentistry, New York, NY; Director, Research Department of Periodontology and Implant Dentistry, New York University College of Dentistry, New York, NY; Affiliated Faculty, Division of Engineering, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates. #Assistant Professor, Department of Prosthodontics, Bauru College of Dentistry, University of São Paulo, Bauru, SP, Brazil. **Adjunct Professor, Director, Material Analysis and Testing Laboratory, Department of Biomaterials and Biomimetics, New York University College of Dentistry, New York, NY.
authors.forename: James Rudolph
authors.initials: JR
authors.lastname: Collins
authors.forename: Ely
authors.initials: E
authors.lastname: Jiménez
authors.forename: Carol
authors.initials: C
authors.lastname: Martínez
authors.forename: Rubén Tobias
authors.initials: RT
authors.lastname: Polanco
authors.forename: Ronaldo
authors.initials: R
authors.lastname: Hirata
authors.forename: Ramy
authors.initials: R
authors.lastname: Mousa
authors.forename: Paulo G
authors.initials: PG
authors.lastname: Coelho
authors.forename: Estevam A
authors.initials: EA
authors.lastname: Bonfante
authors.forename: Nick
authors.initials: N
authors.lastname: Tovar
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D018786:Bone Substitutes; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014081:Tooth Extraction; D020390:Tooth Socket / Q000473:pathology*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D018786:Bone Substitutes