title: Re-feeding rats a high-sucrose diet after 3 days of starvation enhances histone H3 acetylation in transcribed region and expression of jejunal GLUT5 gene.
abstract: Fasting for 3 days leads to reduction in the expression of GLUT5 and SGLT1 genes in jejunum. Re-feeding a high-sucrose diet in fasted rats enhanced mRNA levels and histone H3 acetylation on transcribed region of GLUT5 gene within 24 h, but not in SGLT1. Responsiveness of jejunal GLUT5 gene is associated with changes in histone H3 acetylation on transcribed region.
authors.affiliation: a Laboratory of Nutritional Physiology , School of Food and Nutritional Sciences, University of Shizuoka , Shizuoka , Japan.
authors.forename: Kazue
authors.initials: K
authors.lastname: Honma
authors.forename: Yuriko
authors.initials: Y
authors.lastname: Masuda
authors.forename: Kazuki
authors.initials: K
authors.lastname: Mochizuki
authors.forename: Toshinao
authors.initials: T
authors.lastname: Goda
mesh_terms: D000107:Acetylation / Q000187:drug effects; D000818:Animals; D019422:Dietary Sucrose / Q000009:adverse effects*; D005786:Gene Expression Regulation / Q000187:drug effects*; D051296:Glucose Transporter Type 5 / Q000235:genetics*; D006657:Histones / Q000378:metabolism*; D007583:Jejunum / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D013217:Starvation; D013997:Time Factors; D014158:Transcription, Genetic / Q000187:drug effects*
chemical_list: D019422:Dietary Sucrose; D051296:Glucose Transporter Type 5; D006657:Histones; D012333:RNA, Messenger
keywords: GLUT5; SGLT1; fasting; histone acetylation; intestine