title: [Casual diagnosis of Gitelman's syndrome].
abstract: Gitelman's syndrome is a renal tubule disease of recessive autosomal inheritance in which the fundamental alteration is found in the distal tubule, specifically at the level of the Na/Cl cotransporter, is sensitive to thiazides, and coded in chromosome 16q. It is characterised by a metabolic alkalosis with normal blood pressure, hypokalaemia, as well as hypomagnesaemia and hypocalciuria, which separate it from Bartter's syndrome. Its diagnosis can be delayed up to the adult age, as patients may remain asymptomatic for long periods of time. The treatment consists of oral supplements of potassium and magnesium, and the use of potassium-sparing diuretics and indomethacin has also been described.
authors.affiliation: Medicina de Familia y Comunitaria, ABS Bordeta-Magraners, Lleida, España. Electronic address: vmartin.lleida.ics@gencat.cat.
authors.forename: V
authors.initials: V
authors.lastname: Martín-Miguel
authors.affiliation: Medicina de Familia y Comunitaria, ABS Bordeta-Magraners, Lleida, España.
authors.forename: M A
authors.initials: MA
authors.lastname: Lafarga-Giribets
authors.affiliation: Medicina de Familia y Comunitaria, ABS Bordeta-Magraners, Lleida, España.
authors.forename: L
authors.initials: L
authors.lastname: Garcia-Esteve
authors.affiliation: Medicina de Familia y Comunitaria, ABS Bordeta-Magraners, Lleida, España.
authors.forename: M D
authors.initials: MD
authors.lastname: Rodrigo-Claverol
mesh_terms: D000328:Adult; D001477:Bartter Syndrome / Q000175:diagnosis*; D062865:Diuretics, Potassium Sparing / Q000627:therapeutic use; D005260:Female; D053579:Gitelman Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D006801:Humans; D007008:Hypokalemia / Q000209:etiology*; D033162:Incidental Findings; D007213:Indomethacin / Q000627:therapeutic use; D008274:Magnesium / Q000627:therapeutic use; D011188:Potassium / Q000627:therapeutic use
chemical_list: D062865:Diuretics, Potassium Sparing; D008274:Magnesium; D011188:Potassium; D007213:Indomethacin
keywords: Alcalosis metabólica; Gitelman's syndrome; Hipopotasemia; Hypokalaemia; Metabolic alkalosis; Síndrome de Gitelman