title: Toxic metals in seminal plasma and in vitro fertilization (IVF) outcomes.
abstract: We measured toxic metals in seminal plasma collected from 30 men using vitro fertilization (IVF), to evaluate associations with semen quality and IVF outcomes. A doubling in Hg-adjusted Pb concentration was associated with 47% lower total motile sperm. Positive associations were suggested for Hg with pregnancy and live birth, adjusted for Cd or Pb. A negative association was suggested for Hg-adjusted Cd with pregnancy. These data add to evidence indicating that toxic metals impact IVF.
authors.affiliation: Department of Environmental Health Sciences, University at Albany, State University of New York, Rensselaer, NY, USA.
authors.forename: Keewan
authors.initials: K
authors.lastname: Kim
authors.affiliation: Department of Environmental Health Sciences, University at Albany, State University of New York, Rensselaer, NY, USA; Department of Epidemiology and Biostatistics, University at Albany, State University of New York, Rensselaer, NY, USA. Electronic address: mbloom@albany.edu.
authors.forename: Michael S
authors.initials: MS
authors.lastname: Bloom
authors.affiliation: The Laboratory of Inorganic and Nuclear Chemistry, Wadsworth Center, New York State Department of Health, Albany, NY, USA.
authors.forename: Pamela C
authors.initials: PC
authors.lastname: Kruger
authors.affiliation: The Laboratory of Inorganic and Nuclear Chemistry, Wadsworth Center, New York State Department of Health, Albany, NY, USA; Department of Environmental Health Sciences, University at Albany, State University of New York, Rensselaer, NY, USA.
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Parsons
authors.affiliation: The Laboratory of Inorganic and Nuclear Chemistry, Wadsworth Center, New York State Department of Health, Albany, NY, USA; Department of Environmental Health Sciences, University at Albany, State University of New York, Rensselaer, NY, USA.
authors.forename: John G
authors.initials: JG
authors.lastname: Arnason
authors.affiliation: Department of Epidemiology and Biostatistics, University at Albany, State University of New York, Rensselaer, NY, USA.
authors.forename: Youjung
authors.initials: Y
authors.lastname: Byun
authors.affiliation: Department of Epidemiology and Biostatistics, University at Albany, State University of New York, Rensselaer, NY, USA.
authors.forename: Stephen
authors.initials: S
authors.lastname: Goins
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California at San Francisco, San Francisco, CA, USA.
authors.forename: Victor Y
authors.initials: VY
authors.lastname: Fujimoto
mesh_terms: D000328:Adult; D002104:Cadmium / Q000009:adverse effects / Q000032:analysis; D005260:Female; D005307:Fertilization in Vitro / Q000009:adverse effects*; D006801:Humans; D007854:Lead / Q000032:analysis / Q000097:blood; D008297:Male; D008628:Mercury / Q000009:adverse effects / Q000032:analysis; D019216:Metals, Heavy / Q000009:adverse effects* / Q000032:analysis; D008875:Middle Aged; D010865:Pilot Projects; D011247:Pregnancy; D012661:Semen / Q000737:chemistry*; D055101:Semen Analysis; D016896:Treatment Outcome
chemical_list: D019216:Metals, Heavy; D002104:Cadmium; D007854:Lead; D008628:Mercury
keywords: Cadmium (Cd); Lead (Pb); Mercury (Hg); Reproduction; Semen; in vitro fertilization (IVF)