title: Treatment of drug-induced gingival overgrowth by full-mouth disinfection: A non-surgical approach.
abstract: BACKGROUND
  Drug-induced gingival overgrowth is a common finding in the modern era. These gingival overgrowths are usually treated by various modalities namely substitution of drugs, surgical, and non-surgical treatment. The recent concept mainly involves full-mouth scaling and root planing (the entire dentition in two visits within 24 hours, i.e., two consecutive days) followed by chair side mouth rinsing by the patient with a 0.2% chlorhexidine solution for 2 minutes and brushing the tongue of the patient with 1% chlorhexidine gel. This is followed by an additional subgingival irrigation (three times, repeated within 10 minutes) of all pockets with a 1% chlorhexidine gel.
  
  
  METHODS
  Twenty patients between the ages of 20 and 50 years with drug-induced gingival overgrowth were treated using the full-mouth disinfection approach. The patients were evaluated at 3 months and 6 months after therapy. The data obtained for plaque index, bleeding on probing index, probing pocket depth, and gingival overgrowth scores were tabulated and compared statistically using the one sample unpaired t test.
  
  
  METHODS
  Statistically significant difference (P < 0.05) was found in PI GBI, PPD, and GO score between baseline, 3 months, and 6 months.
  
  
  RESULTS
  All clinical parameters improved significantly after therapy without the need of further surgical treatment.
  
  
  CONCLUSIONS
  Full-mouth disinfection might be a beneficial treatment concept in patients with drug-induced gingival overgrowth, thus decreasing the need for surgical therapy.
authors.affiliation: Department of Periodontics, Rungta College of Dental Sciences and Research, Bhilai, Chhattisgarh, India.
authors.forename: Aena Jain
authors.initials: AJ
authors.lastname: Pundir
authors.affiliation: Department of Oral Pathology, Rungta College of Dental Sciences and Research, Bhilai, Chhattisgarh, India.
authors.forename: Siddharth
authors.initials: S
authors.lastname: Pundir
authors.affiliation: Department of Periodontics, Rungta College of Dental Sciences and Research, Bhilai, Chhattisgarh, India.
authors.forename: R K
authors.initials: RK
authors.lastname: Yeltiwar
authors.affiliation: Department of Periodontics, Rungta College of Dental Sciences and Research, Bhilai, Chhattisgarh, India.
authors.forename: Sana
authors.initials: S
authors.lastname: Farista
authors.affiliation: Department of Periodontics, Rungta College of Dental Sciences and Research, Bhilai, Chhattisgarh, India.
authors.forename: V
authors.initials: V
authors.lastname: Gopinath
authors.affiliation: Department of Periodontics, Rungta College of Dental Sciences and Research, Bhilai, Chhattisgarh, India.
authors.forename: T S
authors.initials: TS
authors.lastname: Srinivas
keywords: Chlorhexidine; drug-induced; gingival overgrowth; non-surgical