title: A new symmetrical tetramer oligostilbenoid containing tetrahydrofuran ring from the stem bark of Dryobalanops lanceolata.
abstract: A new tetramer oligostilbenoid possessing tetrahydrofuran ring, malaysianol C (1), was isolated from the acetone extract of the stem bark of Dryobalanops lanceolata, together with four known oligostilbenoids nepalensinol E (2), ϵ-viniferin (3), laevifonol (4), and ampelopsin F (5). The structures of isolated compounds were elucidated on the basis of spectral evidence. The antibacterial activity of the isolated compounds was evaluated using resazurin microtitre-plate assay, whereas the cytotoxic activity was tested using MTT assay. The plausible biogenetic routes of the isolated compounds are also discussed.
authors.affiliation: a Faculty of Applied Sciences, Universiti Teknologi MARA , 40450 Shah Alam , Selangor Darul Ehsan , Malaysia.
authors.forename: Norizan
authors.initials: N
authors.lastname: Ahmat
authors.forename: Agustono
authors.initials: A
authors.lastname: Wibowo
authors.forename: Sharifah Aminah Syed
authors.initials: SA
authors.lastname: Mohamad
authors.forename: Anis Lou Muhammad
authors.initials: AL
authors.lastname: Low
authors.forename: Adila Sahida
authors.initials: AS
authors.lastname: Sufian
authors.forename: Muhd Izwan Muhd
authors.initials: MI
authors.lastname: Yusof
authors.forename: Jalifah
authors.initials: J
authors.lastname: Latip
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D053958:Dipterocarpaceae / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D008296:Malaysia; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D013237:Stereoisomerism; D013267:Stilbenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D000972:Antineoplastic Agents, Phytogenic; D001572:Benzofurans; D005419:Flavonoids; D005663:Furans; D010936:Plant Extracts; D013267:Stilbenes; C000594273:malaysianol C; C106407:ampelopsin; C018674:tetrahydrofuran; C091891:epsilon-viniferin
keywords: Dipterocarpaceae; Dryobalanops lanceolata; antibacterial; cytotoxicity; malaysianol C; oligostilbenoid