title: Inner and outer central retinal findings after surgery for rhegmatogenous retinal detachment using different spectral-domain optical coherence tomography devices.
abstract: OBJECTIVE
  The aim of the study was to analyse macular changes after rhegmatogenous retinal detachment (RRD) repair using spectral-domain optical coherence tomography (SD-OCT).
  
  
  METHODS
  Forty eyes with macula-on and 27 eyes with macula-off RRD underwent scleral buckling or vitrectomy and were postoperatively imaged using 2 SD-OCT devices (Cirrus® HD-OCT, RTVue-100®). Measurement of total and inner macular thickness consisting of ganglion cell layer + inner plexiform layer (GCL-IPL) using Cirrus or retinal nerve fibre layer + ganglion cell layer + inner plexiform layer (RNFL-GCL-IPL) using RTVue was performed. Results of inner macular thickness were compared with image results of 40 healthy controls. Qualitative analysis of inner and outer retinal layers was additionally assessed.
  
  
  RESULTS
  Measurement of overall retinal thickness within the 9 ETDRS sectors was highly correlated between both OCTs (Pearson's r, range 0.88-0.99; p < 0.001). Correlation of RNFL-GCL-IPL complex between OCTs was excellent in both surgery groups (Pearson's r, range 0.73-0.88; p < 0.001) and normal controls (Pearson's r, range 0.79-0.90; p < 0.001). The RNFL-GCL-IPL complex was thicker in both surgery groups compared to normal controls using Cirrus. Outer retinal findings of macula-off patients were seen in four eyes (14.8 %). Visual acuity (VA) significantly improved in both groups independent of preoperative VA or duration of symptoms.
  
  
  CONCLUSIONS
  Agreement between both OCTs was excellent for overall and inner retinal thickness, although RTVue measured a thicker RNFL-GCL-IPL complex. Thinning of inner retinal layers as a potential cause of poor VA was rarely detected, possibly due to tractional changes at the vitreomacular interface. VA improved even in patients with macula-involving RRD.
authors.affiliation: Department of Ophthalmology, University of Würzburg, Josef-Schneider-Str. 11, Würzburg, 97080, Germany, j.matlach@augenklinik.uni-wuerzburg.de.
authors.forename: Juliane
authors.initials: J
authors.lastname: Matlach
authors.forename: Bärbel
authors.initials: B
authors.lastname: Pflüger
authors.forename: Johannes
authors.initials: J
authors.lastname: Hain
authors.forename: Winfried
authors.initials: W
authors.lastname: Göbel
mesh_terms: D000368:Aged; D058450:Endotamponade; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology*; D011184:Postoperative Period; D012163:Retinal Detachment / Q000175:diagnosis / Q000601:surgery*; D012165:Retinal Ganglion Cells / Q000473:pathology*; D055211:Retinal Photoreceptor Cell Inner Segment / Q000473:pathology; D055214:Retinal Photoreceptor Cell Outer Segment / Q000473:pathology; D012591:Scleral Buckling; D041623:Tomography, Optical Coherence / Q000295:instrumentation*; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy