title: Brain plasticity-based therapeutics.
abstract: The primary objective of this review article is to summarize how the neuroscience of brain plasticity, exploiting new findings in fundamental, integrative and cognitive neuroscience, is changing the therapeutic landscape for professional communities addressing brain-based disorders and disease. After considering the neurological bases of training-driven neuroplasticity, we shall describe how this neuroscience-guided perspective distinguishes this new approach from (a) the more-behavioral, traditional clinical strategies of professional therapy practitioners, and (b) an even more widely applied pharmaceutical treatment model for neurological and psychiatric treatment domains. With that background, we shall argue that neuroplasticity-based treatments will be an important part of future best-treatment practices in neurological and psychiatric medicine.
authors.affiliation: Posit Science Corporation San Francisco, CA, USA.
authors.forename: Michael M
authors.initials: MM
authors.lastname: Merzenich
authors.affiliation: Posit Science Corporation San Francisco, CA, USA ; Medical Research, Department of Veteran Affairs Martinez, CA, USA.
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Van Vleet
authors.affiliation: Posit Science Corporation San Francisco, CA, USA ; Department of Optometry, University of California at Berkeley Berkeley, CA, USA.
authors.forename: Mor
authors.initials: M
authors.lastname: Nahum
keywords: aging; brain plasticity; computerized training; hemispatial neglect; neuroplasticity; schizophrenia