title: Localization of NADPH production: a wheel within a wheel.
abstract: In this issue of Molecular Cell, Lewis et al. (2014) describe a new method to determine where in the cell NADPH is produced, contributing to a growing appreciation that the THF cycle is an important source of mitochondrial NADPH.
authors.affiliation: Cancer Research UK Beatson Institute, Switchback Road, Glasgow G61 1BD, UK.
authors.forename: Oliver D K
authors.initials: OD
authors.lastname: Maddocks
authors.affiliation: Cancer Research UK Beatson Institute, Switchback Road, Glasgow G61 1BD, UK.
authors.forename: Christiaan F
authors.initials: CF
authors.lastname: Labuschagne
authors.affiliation: Cancer Research UK Beatson Institute, Switchback Road, Glasgow G61 1BD, UK. Electronic address: k.vousden@beatson.gla.ac.uk.
authors.forename: Karen H
authors.initials: KH
authors.lastname: Vousden
mesh_terms: D003600:Cytosol / Q000378:metabolism*; D006801:Humans; D008928:Mitochondria / Q000378:metabolism*; D009249:NADP / Q000378:metabolism*
chemical_list: D009249:NADP