title: Hematoma shape, hematoma size, Glasgow coma scale score and ICH score: which predicts the 30-day mortality better for intracerebral hematoma?
abstract: OBJECTIVE
  To investigate the performance of hematoma shape, hematoma size, Glasgow coma scale (GCS) score, and intracerebral hematoma (ICH) score in predicting the 30-day mortality for ICH patients. To examine the influence of the estimation error of hematoma size on the prediction of 30-day mortality.
  
  
  METHODS
  This retrospective study, approved by a local institutional review board with written informed consent waived, recruited 106 patients diagnosed as ICH by non-enhanced computed tomography study. The hemorrhagic shape, hematoma size measured by computer-assisted volumetric analysis (CAVA) and estimated by ABC/2 formula, ICH score and GCS score was examined. The predicting performance of 30-day mortality of the aforementioned variables was evaluated. Statistical analysis was performed using Kolmogorov-Smirnov tests, paired t test, nonparametric test, linear regression analysis, and binary logistic regression. The receiver operating characteristics curves were plotted and areas under curve (AUC) were calculated for 30-day mortality. A P value less than 0.05 was considered as statistically significant.
  
  
  RESULTS
  The overall 30-day mortality rate was 15.1% of ICH patients. The hematoma shape, hematoma size, ICH score, and GCS score all significantly predict the 30-day mortality for ICH patients, with an AUC of 0.692 (P = 0.0018), 0.715 (P = 0.0008) (by ABC/2) to 0.738 (P = 0.0002) (by CAVA), 0.877 (P<0.0001) (by ABC/2) to 0.882 (P<0.0001) (by CAVA), and 0.912 (P<0.0001), respectively.
  
  
  CONCLUSIONS
  Our study shows that hematoma shape, hematoma size, ICH scores and GCS score all significantly predict the 30-day mortality in an increasing order of AUC. The effect of overestimation of hematoma size by ABC/2 formula in predicting the 30-day mortality could be remedied by using ICH score.
authors.affiliation: Department of Radiology, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, Republic of China.
authors.forename: Chih-Wei
authors.initials: CW
authors.lastname: Wang
authors.affiliation: Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan, Republic of China.
authors.forename: Yi-Jui
authors.initials: YJ
authors.lastname: Liu
authors.affiliation: Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan, Republic of China.
authors.forename: Yi-Hsiung
authors.initials: YH
authors.lastname: Lee
authors.affiliation: Department of Neurological Surgery, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, Republic of China.
authors.forename: Dueng-Yuan
authors.initials: DY
authors.lastname: Hueng
authors.affiliation: Department of Pediatrics, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, Republic of China.
authors.forename: Hueng-Chuen
authors.initials: HC
authors.lastname: Fan
authors.affiliation: Department of Neurology, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, Republic of China.
authors.forename: Fu-Chi
authors.initials: FC
authors.lastname: Yang
authors.affiliation: Department of Radiology, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, Republic of China.
authors.forename: Chun-Jen
authors.initials: CJ
authors.lastname: Hsueh
authors.affiliation: Department of Radiology, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, Republic of China.
authors.forename: Hung-Wen
authors.initials: HW
authors.lastname: Kao
authors.affiliation: Department of Radiology, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, Republic of China.
authors.forename: Chun-Jung
authors.initials: CJ
authors.lastname: Juan
authors.affiliation: Department of Radiology, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, Republic of China.
authors.forename: Hsian-He
authors.initials: HH
authors.lastname: Hsu
mesh_terms: D019540:Area Under Curve; D002543:Cerebral Hemorrhage / Q000175:diagnosis* / Q000401:mortality*; D054893:Cone-Beam Computed Tomography; D015600:Glasgow Coma Scale; D006406:Hematoma / Q000473:pathology*; D006801:Humans; D011237:Predictive Value of Tests; D012044:Regression Analysis; D012107:Research Design; D012189:Retrospective Studies; D018709:Statistics, Nonparametric