title: [Bone defect reconstruction in bone sarcoma surgery: tumour endoprosthesis versus biological reconstruction].
abstract: BACKGROUND
  Primary bone sarcomas typically arise in the long bones and the pelvis of children and adolescence but may also occur in adults. Meta/diaphysial tumour involvement resulting in the necessity of a joint replacement is more common than diaphysial tumour sites.
  
  
  OBJECTIVE
  In the treatment of these tumours, both endoprosthetic replacement and biological reconstruction techniques are used. Each technique has method-specific advantages and disadvantages.
  
  
  RESULTS
  To choose the appropriate surgical method, a multitude of influencing parameters need to be considered. The age at treatment (soft tissue situation/estimated growth/biological potential of the bone), therapeutic concept (palliative vs. curative), the tumour site (upper/lower extremity), tumour expansion (diaphysis/metaphysis) and oncological treatment concept (chemotherapy/radiotherapy) are key factors significantly influencing the surgical technique in terms of functional outcome and longevity of the reconstruction.
  
  
  CONCLUSIONS
  Surgical treatment of bone sarcoma requires broad-based experience of the oncological surgeon. Knowledge of the different surgical technics and reconstruction methods is decisive to offer the individual patient the best oncological and functional outcome.
authors.affiliation: Klinik und Poliklinik für allgemeine Orthopädie und Tumororthopädie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Deutschland, streitb@ukmuenster.de.
authors.forename: A
authors.initials: A
authors.lastname: Streitbürger
authors.forename: G
authors.initials: G
authors.lastname: Gosheger
authors.forename: R
authors.initials: R
authors.lastname: Dieckmann
authors.forename: M
authors.initials: M
authors.lastname: Nottrott
authors.forename: H
authors.initials: H
authors.lastname: Ahrens
authors.forename: J
authors.initials: J
authors.lastname: Hardes
mesh_terms: D000328:Adult; D001705:Bioprosthesis; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D003131:Combined Modality Therapy; D019317:Evidence-Based Medicine; D006801:Humans; D007595:Joint Prosthesis; D012516:Osteosarcoma / Q000000981:diagnostic imaging / Q000601:surgery*; D011859:Radiography; D019651:Plastic Surgery Procedures / Q000295:instrumentation / Q000379:methods*