title: Reactions in elastomeric nanoreactors reveal the role of force on the kinetics of the Huisgen reaction on surfaces.
abstract: The force dependence of the copper-free Huisgen cycloaddition between an alkyne and a surface-bound azide was examined in elastomeric nanoreactors. These studies revealed that pressure and chain length are critical factors that determine the reaction rate. These experiments demonstrate the central role of pressure and surface structure on interfacial processes that are increasingly important in biology, materials science, and nanotechnology.
authors.affiliation: Department of Chemistry, University of Miami , Coral Gables, Florida 33146, United States.
authors.forename: Xu
authors.initials: X
authors.lastname: Han
authors.forename: Shudan
authors.initials: S
authors.lastname: Bian
authors.forename: Yong
authors.initials: Y
authors.lastname: Liang
authors.forename: K N
authors.initials: KN
authors.lastname: Houk
authors.forename: Adam B
authors.initials: AB
authors.lastname: Braunschweig