title: Solitary fibrous tumor of the central nervous system: report of 2 cases and review of literature.
abstract: Solitary fibrous tumors (SFTs) rarely occur in the central nervous system (CNS). Involvement of the brainstem and pineal gland is rarely recorded. Herein, we represent 2 cases of SFTs and firstly report SFT of the pineal gland. Cranial MR imaging showed isointense to hypointense signal intensity, and marked enhancement. Microscopically, the tumors showed characteristic "patternless-pattern" architecture. Elongated tumour cells formed fascicles alternating with hypocellular densely collagenous stroma. Immunohistochemistry for CD34, BCL2, and CD99 favors the definitive diagnosis of SFT. It is difficult to predict prognosis in patients with intraventricular SFT. In general, complete surgical resection may offer the best chance of a favorable clinical outcome.
authors.affiliation: Department of Imaging Center, Nanfang Hospital, Southern Medical University Guangzhou, China.
authors.forename: Ge
authors.initials: G
authors.lastname: Wen
authors.affiliation: Department of Imaging Center, Nanfang Hospital, Southern Medical University Guangzhou, China.
authors.forename: Meifang
authors.initials: M
authors.lastname: Li
authors.affiliation: Department of Pathology, School of Basic Medical Sciences, Southern Medical University Guangzhou, China.
authors.forename: Lijun
authors.initials: L
authors.lastname: Xu
authors.affiliation: Department of Imaging Center, Nanfang Hospital, Southern Medical University Guangzhou, China.
authors.forename: Peiqian
authors.initials: P
authors.lastname: Hu
authors.affiliation: Department of Radiology, Nanfang Hospital, Southern Medical University Guangzhou, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Liao
authors.affiliation: Department of Pathology, Nanfang Hospital, Southern Medical University Guangzhou, China.
authors.forename: Chuang
authors.initials: C
authors.lastname: Lin
authors.affiliation: Department of Pathology, School of Basic Medical Sciences, Southern Medical University Guangzhou, China ; Department of Pathology, Nanfang Hospital, Southern Medical University Guangzhou, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Zhao
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D020295:Brain Stem Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D010871:Pinealoma / Q000473:pathology*; D054364:Solitary Fibrous Tumors / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor
keywords: CD34; Solitary fibrous tumor; central nervous system; immunohistochemistry; magnetic resonance imaging