title: Exploring luminescence-based temperature sensing using protein-passivated gold nanoclusters.
abstract: We explore the analytical performance and limitations of optically monitoring aqueous-phase temperature using protein-protected gold nanoclusters (AuNCs). Although not reported elsewhere, we find that these bio-passivated AuNCs show pronounced hysteresis upon thermal cycling. This unwanted behaviour can be eliminated by several strategies, including sol-gel coating and thermal denaturation of the biomolecular template, introducing protein-templated AuNC probes as viable nanothermometers.
authors.affiliation: Department of Chemistry, University of Missouri-Columbia, Columbia, MO 65211, USA. bakergar@missouri.edu.
authors.forename: Xi
authors.initials: X
authors.lastname: Chen
authors.forename: Jeremy B
authors.initials: JB
authors.lastname: Essner
authors.forename: Gary A
authors.initials: GA
authors.lastname: Baker
mesh_terms: D006046:Gold / Q000737:chemistry*; D049449:Luminescence; D053768:Metal Nanoparticles / Q000737:chemistry*; D008958:Models, Molecular; D012710:Serum Albumin, Bovine / Q000737:chemistry*; D013696:Temperature; D062125:Thermometry / Q000379:methods*
chemical_list: D012710:Serum Albumin, Bovine; D006046:Gold