title: The Paediatric migraine disability assessment score is a useful tool for evaluating prophylactic migraine treatment.
abstract: OBJECTIVE
  There is a need for an objective assessment scoring system to evaluate the effectiveness of prophylactic drugs in paediatric migraine, and the aim of this study was to evaluate the Paediatric Migraine Disability Assessment Score (PedMIDAS).
  
  
  METHODS
  We recruited 88 children aged between 6 and 17 years of age with migraine. The 53 children in the treatment group were divided into three groups according to the prophylactic drug they received topiramate, flunarizine and propranolol and assessed using PedMIDAS before the start of treatment and 3 and 6 months after treatment. The 35 patients in the control group did not receive prophylactic treatment and were assessed with PedMIDAS on three occasions, 3 months apart.
  
  
  RESULTS
  Topiramate, propranolol and flunarizine treatments significantly decreased PedMIDASs and were shown to be effective in improving the patients' quality of life. Topiramate and propranolol were more effective than flunarizine. The number of days on analgesic treatment significantly decreased in the patients who had received topiramate and propranolol treatments (p < 0.05), but remained unchanged in the flunarizine prophylaxis group (p > 0.05).
  
  
  CONCLUSIONS
  The PedMIDAS scoring system is useful in evaluating the efficacy of prophylactic therapy in paediatric migraine. Topiramate and propranolol lowered the PedMIDASs better than flunarizine.
authors.affiliation: Division of Pediatric Neurology, Dokuz Eylul University Hospital, Izmir, Turkey.
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Topcu
authors.affiliation: Division of Pediatric Neurology, Dokuz Eylul University Hospital, Izmir, Turkey.
authors.forename: Semra
authors.initials: S
authors.lastname: Hiz Kurul
authors.affiliation: Division of Pediatric Neurology, Dokuz Eylul University Hospital, Izmir, Turkey.
authors.forename: Erhan
authors.initials: E
authors.lastname: Bayram
authors.affiliation: Department of Public Health, Katip Celebi University, Izmir, Turkey.
authors.forename: Kaan
authors.initials: K
authors.lastname: Sozmen
authors.affiliation: Division of Pediatric Neurology, Dokuz Eylul University Hospital, Izmir, Turkey.
authors.forename: Uluc
authors.initials: U
authors.lastname: Yis
mesh_terms: D000293:Adolescent; D002648:Child; D004185:Disability Evaluation; D005444:Flunarizine / Q000627:therapeutic use*; D005632:Fructose / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008881:Migraine Disorders / Q000175:diagnosis* / Q000517:prevention & control*; D011433:Propranolol / Q000627:therapeutic use*; D000077236:Topiramate; D016896:Treatment Outcome
chemical_list: D000077236:Topiramate; D005632:Fructose; D011433:Propranolol; D005444:Flunarizine
keywords: Child; Flunarizine; Migraine; PedMIDAS; Propranolol; Topiramate