title: EVI1 overexpression is a poor prognostic factor in pediatric patients with mixed lineage leukemia-AF9 rearranged acute myeloid leukemia.
authors.affiliation: Department of Human Health Sciences, Kyoto University, Japan.
authors.forename: Hidemasa
authors.initials: H
authors.lastname: Matsuo
authors.affiliation: Department of Human Health Sciences, Kyoto University, Japan.
authors.forename: Mio
authors.initials: M
authors.lastname: Kajihara
authors.affiliation: Department of Pediatrics, Tokyo Medical and Dental University (TMDU), Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Tomizawa
authors.affiliation: Department of Nutritional Science, Aichi Gakuin University, Nisshin, Japan.
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Watanabe
authors.affiliation: Clinical Research Center, National Hospital Organization Nagoya Medical Center, Japan.
authors.forename: Akiko Moriya
authors.initials: AM
authors.lastname: Saito
authors.affiliation: Epidemiology and Clinical Research Center for Children's Cancer, National Center for Child Health and Development, Tokyo, Japan.
authors.forename: Junichiro
authors.initials: J
authors.lastname: Fujimoto
authors.affiliation: Clinical Research Center, National Hospital Organization Nagoya Medical Center, Japan.
authors.forename: Keizo
authors.initials: K
authors.lastname: Horibe
authors.affiliation: Department of Human Health Sciences, Kyoto University, Japan.
authors.forename: Kumi
authors.initials: K
authors.lastname: Kodama
authors.affiliation: Department of Pediatrics, Kyoto University, Japan.
authors.forename: Mayu
authors.initials: M
authors.lastname: Tokumasu
authors.affiliation: Department of Human Health Sciences, Kyoto University, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Itoh
authors.affiliation: Department of Pediatrics, National Hospital Organization Fukuoka-Higashi Medical Center, Koga, Japan.
authors.forename: Hideki
authors.initials: H
authors.lastname: Nakayama
authors.affiliation: Department of Pediatrics, St. Marianna University School of Medicine, Kawasaki, Japan.
authors.forename: Akitoshi
authors.initials: A
authors.lastname: Kinoshita
authors.affiliation: Department of Pediatrics, Shiga University of Medical Science, Otsu, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Taga
authors.affiliation: Department of Pediatrics, National Hospital Organization Osaka National Hospital, Japan.
authors.forename: Akio
authors.initials: A
authors.lastname: Tawa
authors.affiliation: Department of Molecular Diagnostics and Therapeutics, Kyoto Prefectural University of Medicine, Japan.
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Taki
authors.affiliation: Department of Pediatrics, Gunma University Graduate School of Medicine, Maebashi, Japan.
authors.forename: Norio
authors.initials: N
authors.lastname: Shiba
authors.affiliation: Department of Hematology and Oncology, Gunma Children's Medical Center, Shibukawa, Japan.
authors.forename: Kentaro
authors.initials: K
authors.lastname: Ohki
authors.affiliation: Department of Hematology and Oncology, Gunma Children's Medical Center, Shibukawa, Japan.
authors.forename: Yasuhide
authors.initials: Y
authors.lastname: Hayashi
authors.affiliation: Department of Pediatrics, National Hospital Organization Nagoya Medical Center, Japan.
authors.forename: Yuka
authors.initials: Y
authors.lastname: Yamashita
authors.affiliation: Department of Pediatrics, Okayama University Hospitaland, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Shimada
authors.affiliation: Department of Pharmacoepidemiology, Kyoto University, Japan.
authors.forename: Shiro
authors.initials: S
authors.lastname: Tanaka
authors.affiliation: Department of Human Health Sciences, Kyoto University, Japan adachiso@kuhp.kyoto-u.ac.jp.
authors.forename: Souichi
authors.initials: S
authors.lastname: Adachi
mesh_terms: D004268:DNA-Binding Proteins / Q000235:genetics*; D015870:Gene Expression; D015321:Gene Rearrangement; D011495:Histone-Lysine N-Methyltransferase; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000401:mortality* / Q000473:pathology; D000074008:MDS1 and EVI1 Complex Locus Protein; D051788:Myeloid-Lymphoid Leukemia Protein / Q000235:genetics*; D011379:Prognosis; D011519:Proto-Oncogenes / Q000235:genetics*; D014157:Transcription Factors / Q000235:genetics*; D014178:Translocation, Genetic
chemical_list: D004268:DNA-Binding Proteins; C497422:KMT2A protein, human; D000074008:MDS1 and EVI1 Complex Locus Protein; C063575:MECOM protein, human; D014157:Transcription Factors; D051788:Myeloid-Lymphoid Leukemia Protein; D011495:Histone-Lysine N-Methyltransferase
keywords: EVI1; MLL; acute myeloid leukemia; pediatrics; prognostic factor