title: Length of storage of transfused red blood cells and risk of prosthetic joint infection after primary knee arthroplasty.
abstract: The aim of our study was to determine the potential influence of blood transfusion and the length of storage of packed red blood cells (RBC) on prosthetic joint infection after primary knee arthroplasty. From November 2007 to November 2009, all variables potentially associated with deep infection were registered in 1331 consecutive patients who underwent total knee arthroplasty. Infection was diagnosed in 32 (2.4%) patients. After adjusting for important variables, blood transfusion with RBCs stored >14days was the strongest predictive factor for prosthetic joint infection within 90days after primary knee arthroplasty (OR: 5.9, 95% CI: 2.6-13.2, P < 0.001). Blood saving techniques are desirable to reduce perioperative blood transfusion.
authors.affiliation: Department of Internal Medicine, University Hospital of Salamanca-IBSAL, Salamanca, Spain.
authors.forename: Sandra P
authors.initials: SP
authors.lastname: Gómez-Lesmes
authors.affiliation: Department of Orthopedic Surgery, Spain.
authors.forename: Eduard
authors.initials: E
authors.lastname: Tornero
authors.affiliation: Department of Orthopedic Surgery, Spain.
authors.forename: Juan C
authors.initials: JC
authors.lastname: Martínez-Pastor
authors.affiliation: Service of Hemotherapy and Hemostasis, Spain.
authors.forename: Arturo
authors.initials: A
authors.lastname: Pereira
authors.affiliation: Department of Internal Medicine, University Hospital of Salamanca-IBSAL, Salamanca, Spain.
authors.forename: Miguel
authors.initials: M
authors.lastname: Marcos
authors.affiliation: Service of Infectious Diseases, IDIBAPS, University of Barcelona, Spain.
authors.forename: Alex
authors.initials: A
authors.lastname: Soriano
mesh_terms: D000368:Aged; D001168:Arthritis / Q000601:surgery*; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D001793:Blood Preservation; D017707:Erythrocyte Transfusion / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000209:etiology*; D016032:Randomized Controlled Trials as Topic; D013997:Time Factors
keywords: arthroplasty; blood transfusion; infection; packed red blood cells; risk factors; time of storage