title: Development of angioimmunoblastic T-cell lymphoma after treatment of diffuse large B-cell lymphoma: a case report and review of literature.
abstract: Cases of diffuse large B-cell lymphoma (DLBCL) arising after the initial diagnosis of angioimmunoblastic T-cell lymphoma (AITL) and DLBCL synchronous with AITL have been reported. To date, there is no report on the subsequent development of AITL in patients with DLBCL. Here we presented a rare case of AITL developing six months after the initial diagnosis of DLBCL. In order to investigate the clinical and molecular features of patients with AITL and DLBCL, we also reviewed the literature on AITL patients developing DLBCL, and patients with composite AITL and DLBCL.
authors.affiliation: Centre of Oncology and Hematology, The First Affiliated Hospital of Guangzhou Medical University Guangzhou, China.
authors.forename: Yaya
authors.initials: Y
authors.lastname: Wang
authors.affiliation: The Department of Pharmacy, The First Affiliated Hospital of Guangzhou Medical University Guangzhou, China.
authors.forename: Bailu
authors.initials: B
authors.lastname: Xie
authors.affiliation: The Department of Pathology, Guangdong General Hospital Guangzhou, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Centre of Oncology and Hematology, The First Affiliated Hospital of Guangzhou Medical University Guangzhou, China.
authors.forename: Zhenqian
authors.initials: Z
authors.lastname: Huang
authors.affiliation: Centre of Oncology and Hematology, The First Affiliated Hospital of Guangzhou Medical University Guangzhou, China.
authors.forename: Huo
authors.initials: H
authors.lastname: Tan
mesh_terms: D000368:Aged; D006801:Humans; D007119:Immunoblastic Lymphadenopathy / Q000473:pathology*; D016130:Immunophenotyping; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology*; D016399:Lymphoma, T-Cell / Q000473:pathology*; D008297:Male; D016609:Neoplasms, Second Primary / Q000473:pathology*
keywords: Angioimmunoblastic T-cell lymphoma; composite lymphoma; diffuse large B-cell lymphoma