title: Evidence of pleiotropy by statins: leukocyte Rho kinase (ROCK) activity and pretreated statin before percutaneous coronary interventions are clinical vascular outcome predictors.
authors.affiliation: Division of Cardiology, Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan; Institute of Clinical Medicine, National Cheng Kung University, Tainan, Taiwan; Cardiovascular Research Center National Cheng-Kung University, Tainan, Taiwan. Electronic address: larry@mail.ncku.edu.tw.
authors.forename: Ping-Yen
authors.initials: PY
authors.lastname: Liu
authors.affiliation: Division of Cardiology, Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan; Institute of Clinical Medicine, National Cheng Kung University, Tainan, Taiwan; Cardiovascular Research Center National Cheng-Kung University, Tainan, Taiwan; Internal Medicine, National Cheng Kung University Hospital Dou-Liou Branch, Yun-Lin County, Taiwan. Electronic address: ptlee31@gmail.com.
authors.forename: Po-Tseng
authors.initials: PT
authors.lastname: Lee
authors.affiliation: Division of Cardiology, Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan; Institute of Clinical Medicine, National Cheng Kung University, Tainan, Taiwan; Cardiovascular Research Center National Cheng-Kung University, Tainan, Taiwan. Electronic address: weiting@info.hosp.ncku.edu.tw.
authors.forename: Wei-Ting
authors.initials: WT
authors.lastname: Chang
authors.affiliation: Division of Cardiology, Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan; Institute of Clinical Medicine, National Cheng Kung University, Tainan, Taiwan; Cardiovascular Research Center National Cheng-Kung University, Tainan, Taiwan. Electronic address: bunnylinn@gmail.com.
authors.forename: Yun-Ling
authors.initials: YL
authors.lastname: Tai
authors.affiliation: Division of Cardiology, Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan; Cardiovascular Research Center National Cheng-Kung University, Tainan, Taiwan. Electronic address: chaotinghsing@gmail.com.
authors.forename: Ting-Hsing
authors.initials: TH
authors.lastname: Chao
authors.affiliation: Division of Cardiology, Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan; Cardiovascular Research Center National Cheng-Kung University, Tainan, Taiwan. Electronic address: appollolee@yahoo.com.tw.
authors.forename: Cheng-Han
authors.initials: CH
authors.lastname: Lee
authors.affiliation: Division of Cardiology, Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan; Cardiovascular Research Center National Cheng-Kung University, Tainan, Taiwan. Electronic address: t025215@ms17.hinet.net.
authors.forename: Yi-Heng
authors.initials: YH
authors.lastname: Li
authors.affiliation: Division of Cardiology, Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan; Cardiovascular Research Center National Cheng-Kung University, Tainan, Taiwan. Electronic address: jyhhong@mail.ncku.edu.tw.
authors.forename: Jyh-Hong
authors.initials: JH
authors.lastname: Chen
authors.affiliation: Division of Cardiology, Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan; Cardiovascular Research Center National Cheng-Kung University, Tainan, Taiwan. Electronic address: tsailm@mail.ncku.edu.tw.
authors.forename: Liang-Miin
authors.initials: LM
authors.lastname: Tsai
authors.affiliation: Division of Cardiology, University of Chicago, IL, USA. Electronic address: jliao@medicine.bsd.uchicago.edu.
authors.forename: James K
authors.initials: JK
authors.lastname: Liao
mesh_terms: D000368:Aged; D004789:Enzyme Activation / Q000187:drug effects / Q000502:physiology; D005260:Female; D058685:Genetic Pleiotropy / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000008:administration & dosage*; D007962:Leukocytes / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects*; D011237:Predictive Value of Tests; D011300:Preoperative Care / Q000379:methods; D016896:Treatment Outcome; D054460:rho-Associated Kinases / Q000378:metabolism*
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D054460:rho-Associated Kinases
keywords: Inflammation; Percutaneous coronary intervention; Rho kinase; Statin