title: An efficient regioselective hydrodifluoromethylation of unactivated alkenes with TMSCF₂CO₂Et at ambient temperature.
abstract: A mild, versatile and efficient method for the regioselective hydrodifluoromethylation of unactivated alkenes has been developed. This Ag-mediated Csp(3)-CF2 bond forming reaction provides easy access to a variety of vicinal α-difluoroacetate-containing alkanes.
authors.affiliation: Department of Chemistry, School of Materials Science and Engineering, Shanghai University, Shanghai 200444, China. jhao@shu.edu.cn wanwen@staff.shu.edu.cn.
authors.forename: Guobin
authors.initials: G
authors.lastname: Ma
authors.forename: Wen
authors.initials: W
authors.lastname: Wan
authors.forename: Jialiang
authors.initials: J
authors.lastname: Li
authors.forename: Qingyang
authors.initials: Q
authors.lastname: Hu
authors.forename: Haizhen
authors.initials: H
authors.lastname: Jiang
authors.forename: Shizheng
authors.initials: S
authors.lastname: Zhu
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.forename: Jian
authors.initials: J
authors.lastname: Hao
mesh_terms: D000085:Acetates / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D054879:Halogenation; D008745:Methylation; D012821:Silanes / Q000737:chemistry*; D012834:Silver / Q000737:chemistry; D013237:Stereoisomerism; D013696:Temperature
chemical_list: D000085:Acetates; D000475:Alkenes; D012821:Silanes; D012834:Silver