title: Local and general anesthetics immediate hypersensitivity reactions.
abstract: Intraoperative anaphylaxis and hypersensitivity reactions in the setting of anesthesia contribute significantly to the morbidity and mortality of surgeries and surgical procedures. Because multiple medications and products are given in a short period of time, identifying the specific cause can be difficult. Neuromuscular blocking agents, antibiotics, and latex are the most common causes of anesthesia-related reactions, though other medications or exposures could be involved. Careful review of anesthetic charts and allergy testing can help identify the underlying cause. The identification of the cause and subsequent prevention of reactions are critical to reduce overall mortality and morbidity related to anesthesia.
authors.affiliation: Division of Allergic Diseases, Mayo Medical School, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.
authors.forename: Gerald W
authors.initials: GW
authors.lastname: Volcheck
authors.affiliation: Department of Anesthesia and Intensive Care, University Hospital of Strasbourg, Nouvel Hôpital Civil, 1 Place de l'Hôpital - BP 426, 67091 Strasbourg Cedex, France. Electronic address: paul-michel.mertes@chru-strasbourg.fr.
authors.forename: Paul Michel
authors.initials: PM
authors.lastname: Mertes
mesh_terms: D000707:Anaphylaxis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D018681:Anesthetics, General / Q000009:adverse effects* / Q000145:classification; D000779:Anesthetics, Local / Q000009:adverse effects* / Q000145:classification; D004342:Drug Hypersensitivity / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control* / Q000628:therapy*; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*
chemical_list: D018681:Anesthetics, General; D000779:Anesthetics, Local
keywords: Allergy; Anaphylaxis; Anesthetics; Perioperative; Skin tests