title: Effects of probiotic yogurt consumption on inflammatory biomarkers in patients with type 2 diabetes.
abstract: BACKGROUND
  The role of inflammatory cytokines in diabetes and its complications has been shown in some studies. The purpose of this study was to compare the effect of probiotic and conventional yogurt on inflammatory markers in patients with type 2 diabetes.
  
  
  METHODS
  Forty-four patients with type 2 diabetes were participated in this randomized, double-blind controlled clinical trial and assigned to two intervention and control groups. The subjects in the intervention group consumed 300 g/d probiotic yogurt and subjects in the control group consumed 300 g/d conventional yogurt for 8 weeks. Anthropometric indices, dietary intakes, and serum levels of glucose, HbA1c, IL-6, TNF-α and hs-CRP were evaluated at the beginning and end of the intervention.
  
  
  RESULTS
  For anthropometric indices and dietary intakes, no significant differences were seen within and between groups post intervention (p> 0.05). The consumption of probiotic yogurt caused significant decrease in HbA1c and TNF-α levels (p= 0.032 and p= 0.040, respectively) in the intervention group.
  
  
  CONCLUSIONS
  It is suggested that probiotic yogurt may be used as an alternative prevention approach and treatment method to control diabetic complications.
authors.affiliation: Hyperlipidemia Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Majid
authors.initials: M
authors.lastname: Mohamadshahi
authors.affiliation: Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Masoud
authors.initials: M
authors.lastname: Veissi
authors.affiliation: Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Haidari
authors.affiliation: Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Hajieh
authors.initials: H
authors.lastname: Shahbazian
authors.affiliation: Department of Laboratory Sciences, School of Para-medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Gholam-Abas
authors.initials: GA
authors.lastname: Kaydani
authors.affiliation: Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Mohammadi
keywords: Glycosylated hemoglobin; Inflammatory biomarkers; Probiotic; Type 2 diabetes