title: Triorchidism: genetic and imaging evaluation in an adult male.
abstract: We report the results of imaging and cytogenetic studies in a case of triorchidism in a 54 years old male without any associated anomaly. A scrotal ultrasonography revealed the presence of two testes within the left hemiscrotum with complete septation and echotexture and vascular flow pattern similar to the vascular flow of the normal right testis. There was no focal abnormal echogenicity suggesting malignancy. Scrotal MRI confirmed two soft-tissue structures in the left hemiscrotum with normal signal intensity at T1w and T2w images. Both testes had a tunica albuginea with low-signal intensity. Cytogenetic analysis resulted in normal male karyotype 46XY. Array-CGH analysis detected the presence of two interstitial rearrangements: a ~120 Kb deletion of chromosome 1 and a ~140 Kb deletion of chromosome 16. Currently there are little details on the functions of both genes.
authors.affiliation: Urological and Andrological Unit, Department of Medicine, Surgery and Neuroscience, Siena. roberto.ponchietti@unisi.it.
authors.forename: Arben
authors.initials: A
authors.lastname: Belba
authors.forename: Valentina
authors.initials: V
authors.lastname: Riversi
authors.forename: Francesca
authors.initials: F
authors.lastname: Mari
authors.forename: Eleonora
authors.initials: E
authors.lastname: Cellesi
authors.forename: Roberto
authors.initials: R
authors.lastname: Ponchietti
mesh_terms: D002869:Chromosome Aberrations; D002900:Chromosomes, Human, 1-3; D002902:Chromosomes, Human, 16-18; D000013:Congenital Abnormalities / Q000000981:diagnostic imaging / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D013737:Testis / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D014463:Ultrasonography