title: The cardioprotective actions of hydrogen sulfide in acute myocardial infarction and heart failure.
abstract: It has now become universally accepted that hydrogen sulfide (H2S), previously considered only as a lethal toxin, has robust cytoprotective actions in multiple organ systems. The diverse signaling profile of H2S impacts multiple pathways to exert cytoprotective actions in a number of pathological states. This paper will review the recently described cardioprotective actions of hydrogen sulfide in both myocardial ischemia/reperfusion injury and congestive heart failure.
authors.affiliation: Department of Pharmacology and Experimental Therapeutics and Cardiovascular Center of Excellence, LSU Health Sciences Center, New Orleans, LA 70112, USA.
authors.forename: David J
authors.initials: DJ
authors.lastname: Polhemus
authors.affiliation: Department of Surgery, Emory University School of Medicine, Atlanta, GA 30322, USA.
authors.forename: John W
authors.initials: JW
authors.lastname: Calvert
authors.affiliation: Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
authors.forename: Javed
authors.initials: J
authors.lastname: Butler
authors.affiliation: Department of Pharmacology and Experimental Therapeutics and Cardiovascular Center of Excellence, LSU Health Sciences Center, New Orleans, LA 70112, USA.
authors.forename: David J
authors.initials: DJ
authors.lastname: Lefer