title: The CROWN initiative: journal editors invite researchers to develop core outcomes in women's health.
abstract: Clinical trials, systematic reviews and guidelines compare beneficial and non-beneficial outcomes following interventions. Often, however, various studies on a particular topic do not address the same outcomes, making it difficult to draw clinically useful conclusions when a group of studies is looked at as a whole. This problem was recently thrown into sharp focus by a systematic review of interventions for preterm birth prevention, which found that among 103 randomised trials, no fewer than 72 different outcomes were reported. There is a growing recognition among clinical researchers that this variability undermines consistent synthesis of the evidence, and that what is needed is an agreed standardised collection of outcomes - a "core outcomes set" - for all trials in a specific clinical area. Recognising that the current inconsistency is a serious hindrance to progress in our specialty, the editors of over 50 journals related to women's health have come together to support The CROWN (CoRe Outcomes in WomeN's health) Initiative.
authors.forename: Khalid
authors.initials: K
authors.lastname: Khan
authors.affiliation: Institute for Clinical Effectiveness and Health Policy (IECS), Buenos Aires, Argentina. reproductivehealthjournal@biomedcentral.com.
authors.forename: José M
authors.initials: JM
authors.lastname: Belizán
mesh_terms: D005260:Female; D006801:Humans; D017063:Outcome Assessment, Health Care; D012107:Research Design; D012108:Research Personnel; D016896:Treatment Outcome; D016387:Women's Health