title: Comparison between Three Rare Cases of Co-Infection with Dengue, Leptospira and Hepatitis E: Is Early Endothelial Involvement the Culprit in Mortality?
abstract: Co-infection in immunocompetent patients is rare. Though co-infection with dengue and leptospira cases is increasingly reported, a co-infection of this combination along with hepatitis E is rarely thought of. Until date only two case of triple co-infection have been reported world-wide. Here, we are reporting a patient with co-infection of dengue, leptospirosis and hepatitis E admitted to our intensive care unit. Early septic shock and increasing procalcitonin in dengue patient raised suspicion of co-infection. Our aim is to educate intensivists about this rare co-infection and hence that timely initiation of appropriate diagnostic, therapeutic and supportive measures can alter outcome favorably.
authors.affiliation: Department of Critical Care Medicine, SGPGIMS, Lucknow, Uttar Pradesh, India.
authors.forename: Rk
authors.initials: R
authors.lastname: Singh
authors.affiliation: Department of Critical Care Medicine, SGPGIMS, Lucknow, Uttar Pradesh, India.
authors.forename: T
authors.initials: T
authors.lastname: Ghatak
authors.affiliation: Department of Critical Care Medicine, SGPGIMS, Lucknow, Uttar Pradesh, India.
authors.forename: S
authors.initials: S
authors.lastname: Saigal
authors.affiliation: Department of Critical Care Medicine, SGPGIMS, Lucknow, Uttar Pradesh, India.
authors.forename: Ak
authors.initials: A
authors.lastname: Baronia
keywords: Co-infection; Dengue; Endothelium; Hepatitis E; Leptospirosis