title: Nuclear medicine procedures in the diagnosis of NET: a historical perspective.
abstract: Novel diagnostic tools and therapies have emerged as a result of the continuous endeavors relating to neuroendocrine tumors (NETs). Nuclear medicine plays a pivotal role in the imaging and treatment of NETs. Somatostatin receptor analogues and metaiodobenzylguanidine remain front-line single-photon emission computed tomography (SPECT) radiotracers in the imaging of NET; their utility has been augmented by the increasing availability of SPECT/CT. Positron emission tomography has been growing rapidly in the imaging of NETs, paralleled by great efforts toward the development of new tracers. Hybrid imaging will play an important role in the future of NETs.
authors.affiliation: PET Unit, Department of Nuclear Medicine, Santa Maria della Misericordia Hospital, Viale Tre Martiri 140, Rovigo 45100, Italy.
authors.forename: Anna Margherita
authors.initials: AM
authors.lastname: Maffione
authors.affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Sellam
authors.initials: S
authors.lastname: Karunanithi
authors.affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Rakesh
authors.initials: R
authors.lastname: Kumar
authors.affiliation: PET Unit, Department of Nuclear Medicine, Santa Maria della Misericordia Hospital, Viale Tre Martiri 140, Rovigo 45100, Italy. Electronic address: rubello.domenico@azisanrovigo.it.
authors.forename: Domenico
authors.initials: D
authors.lastname: Rubello
authors.affiliation: Department of Radiology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.
authors.forename: Abass
authors.initials: A
authors.lastname: Alavi
mesh_terms: D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D018358:Neuroendocrine Tumors / Q000000981:diagnostic imaging* / Q000266:history; D049268:Positron-Emission Tomography / Q000266:history*; D019275:Radiopharmaceuticals / Q000266:history; D015899:Tomography, Emission-Computed, Single-Photon / Q000266:history*
chemical_list: D019275:Radiopharmaceuticals
keywords: Imaging; Neuroendocrine tumor; Nuclear medicine; PET; SPECT; Therapy; Treatment