title: α-Selective ribofuranosylation of alcohols with ribofuranosyl iodides and triphenylphosphine oxide.
abstract: Ribofuranosylation of a variety of alcohols with ribofuranosyl iodides in the presence of a base and triphenylphosphine oxide afforded the corresponding α-ribofuranosides with diastereoselectivities ≥ 99:1. This reaction can be carried out under mildly basic conditions and is thus compatible with acid-sensitive functional groups.
authors.affiliation: Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University , 1-1 Yanagido, Gifu 501-1193, Japan.
authors.forename: Natsuhisa
authors.initials: N
authors.lastname: Oka
authors.forename: Rin
authors.initials: R
authors.lastname: Kajino
authors.forename: Kaoru
authors.initials: K
authors.lastname: Takeuchi
authors.forename: Haruna
authors.initials: H
authors.lastname: Nagakawa
authors.forename: Kaori
authors.initials: K
authors.lastname: Ando
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D002384:Catalysis; D007454:Iodides / Q000737:chemistry*; D015394:Molecular Structure; D009943:Organophosphorus Compounds / Q000737:chemistry*; D012263:Ribonucleosides / Q000737:chemistry*
chemical_list: D000438:Alcohols; D007454:Iodides; D009943:Organophosphorus Compounds; D012263:Ribonucleosides; C063888:triphenylphosphine oxide