title: Why epistasis is important for tackling complex human disease genetics.
abstract: Epistasis has been dismissed by some as having little role in the genetic architecture of complex human disease. The authors argue that this view is the result of a misconception and explain why exploring epistasis is likely to be crucial to understanding and predicting complex disease.
authors.affiliation: Department of Biological Sciences, North Carolina State University, Raleigh, NC 27695, USA.
authors.forename: Trudy Fc
authors.initials: TF
authors.lastname: Mackay
authors.affiliation: Institute for Quantitative Biomedical Sciences, Geisel School of Medicine, Dartmouth College, Lebanon, NH 03756, USA.
authors.forename: Jason H
authors.initials: JH
authors.lastname: Moore