title: High prevalence of vitamin D insufficiency/deficiency in Dutch multi-ethnic obese children.
abstract: Vitamin D insufficiency/deficiency is common among non-white children; however, little is known about the prevalence of vitamin D insufficiency/deficiency in non-white obese children living in the Netherlands. Therefore, a retrospective analysis was performed on data from multi-ethnic Dutch children and adolescents 6–18 years who visited the obesity outpatient clinic in 2012–2013. We performed anthropometric measurements, oral glucose tolerance test, and measured 25(OH)D and lipid levels. Vitamin D insufficiency was defined as 25(OH)D levels 37.5- <50 nmol/L and vitamin D deficiency as 25(OH)D <37.5 nmol/L. In total, data from 387 children were obtained (mean age 11.6 years, 41.1 % boys, 10.3 % Dutch native, 25.6 % Turkish, 24.5 % Moroccan, 7.5 % African Surinamese, and 7.0 % West African). The median 25(OH)D level was 34 (range 12–105) nmol/L. In total, 17.8 % were vitamin D sufficient, 24.5 % with vitamin D insufficiency, and 57.6 % with vitamin D deficiency. Obese ethnic children showed the highest (87.5 %) and normal weight white children showed the lowest (20.0 %) prevalence of vitamin D insufficiency/deficiency . Conclusion: Vitamin D insufficiency and deficiency is extremely prevalent in treatment-seeking obese ethnic children. However, there was no evidence of an effect of vitamin D status on various components of the metabolic syndrome in our cohort.
authors.forename: Nalini
authors.initials: N
authors.lastname: Radhakishun
authors.forename: Mariska
authors.initials: M
authors.lastname: van Vliet
authors.forename: Ines
authors.initials: I
authors.lastname: von Rosenstiel
authors.forename: Olivier
authors.initials: O
authors.lastname: Weijer
authors.forename: Michaela
authors.initials: M
authors.lastname: Diamant
authors.forename: Jos
authors.initials: J
authors.lastname: Beijnen
authors.forename: Dees
authors.initials: D
authors.lastname: Brandjes
mesh_terms: D000293:Adolescent; D000886:Anthropometry; D002648:Child; D005006:Ethnicity; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications; D009426:Netherlands / Q000453:epidemiology; D063766:Pediatric Obesity / Q000208:ethnology*; D015995:Prevalence; D012189:Retrospective Studies; D014807:Vitamin D / Q000031:analogs & derivatives / Q000097:blood; D014808:Vitamin D Deficiency / Q000097:blood / Q000208:ethnology*
chemical_list: D008055:Lipids; D014807:Vitamin D; C104450:25-hydroxyvitamin D