title: Chronic inflammatory arthritis prevalence estimates for children and adolescents in three Canadian provinces.
abstract: There is a paucity of published population-based estimates of the prevalence of chronic inflammatory arthritis in the pediatric population. We used administrative health data to estimate the prevalence of chronic inflammatory arthritis in individuals ≤18 years in three Canadian provinces: Quebec, Manitoba, and Saskatchewan. Cases aged ≤18 years were identified by meeting any one of the following criteria: (a) ≥1 hospital discharge abstract with an ICD-9 code of 714 or ICD-10-CA codes of M05, M06 or M08, or (b) ≥2 ICD-9 714 billing codes ≥8 weeks apart, but within 2 years, or (c) ≥1 ICD-9 714 billing code by a rheumatologist. Crude prevalence estimates per 10,000 population were estimated with 95 % confidence intervals (CIs). Prevalence estimates were 11.7 per 10,000 individuals ≤18 years of age in Manitoba, 9.8 per 10,000 in Saskatchewan, and 8.0 per 10,000 in Quebec. In pairwise comparisons of rate differences, Manitoba and Saskatchewan had higher estimates than Quebec. Prevalence estimates were higher for females than males, with a difference of 5.9 cases per 10,000 residents (95 % CI 5.1, 6.7). Saskatchewan was the only province with a higher estimate in urban compared to rural residents (5.2, 95 % CI 2.5, 8.0). Variations in provincial estimates may be due to differences in underlying population characteristics. Although these estimates have face validity and are in keeping with the range of previously published pediatric prevalence estimates, studies to establish the empiric validity of case-finding algorithms are needed to advance research in pediatric chronic disease epidemiology.
authors.affiliation: Department of Paediatrics, Royal University Hospital, University of Saskatchewan, 103 Hospital Drive, Saskatoon, SK, S7N 0C8, Canada, natalie_shiff@hotmail.com.
authors.forename: Natalie Jane
authors.initials: NJ
authors.lastname: Shiff
authors.forename: Lisa M
authors.initials: LM
authors.lastname: Lix
authors.forename: Kiem
authors.initials: K
authors.lastname: Oen
authors.forename: Lawrence
authors.initials: L
authors.lastname: Joseph
authors.forename: Ciaran
authors.initials: C
authors.lastname: Duffy
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Stringer
authors.forename: Lori B
authors.initials: LB
authors.lastname: Tucker
authors.forename: Lawrence W
authors.initials: LW
authors.lastname: Svenson
authors.forename: Patrick
authors.initials: P
authors.lastname: Belisle
authors.forename: Sasha
authors.initials: S
authors.lastname: Bernatsky
mesh_terms: D000293:Adolescent; D001171:Arthritis, Juvenile / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D016208:Databases, Factual; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008350:Manitoba / Q000453:epidemiology; D015995:Prevalence; D011792:Quebec / Q000453:epidemiology; D012525:Saskatchewan / Q000453:epidemiology; D017678:Sex Distribution