title: High performance of a palladium phosphinooxazoline catalyst in the asymmetric arylation of cyclic N-sulfonyl ketimines.
abstract: A cationic palladium complex with a chiral phosphine-oxazoline ligand (iPr-phox) showed high catalytic activity and enantioselectivity in the asymmetric addition of arylboronic acids to six-membered cyclic N-sulfonyl ketimines to give high yields of the corresponding chiral cyclic sulfamidates with 96-99.9% ee. The products have tetrasubstituted stereogenic centers with an amino group and a triaryl or alkyldiaryl group as substituents.
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543 (Singapore).
authors.forename: Chunhui
authors.initials: C
authors.lastname: Jiang
authors.forename: Yixin
authors.initials: Y
authors.lastname: Lu
authors.forename: Tamio
authors.initials: T
authors.lastname: Hayashi
keywords: arylboronic acids; asymmetric arylation; chiral amines; cyclic sulfonyl ketimines; palladium