title: Mild and versatile nitrate-promoted C-H bond fluorination.
abstract: A novel and facile C-H bond fluorination proceeds under remarkably mild conditions (close to room temperature in most cases). Both aromatic and olefinic C(sp(2))-H bonds with a wide range of electronic properties are selectively fluorinated in the presence of a catalytic amount of simple, cheap, and nontoxic nitrate as the promoter. A Pd(II)/Pd(IV) catalytic cycle that is initiated by an in situ generated cationic [Pd(NO3)](+) species was proposed based on preliminary mechanistic studies.
authors.affiliation: Catalytic Hydrogenation Research Center, State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, Zhejiang University of Technology, Hangzhou 310014 (P.R. China).
authors.forename: Shao-Jie
authors.initials: SJ
authors.lastname: Lou
authors.forename: Dan-Qian
authors.initials: DQ
authors.lastname: Xu
authors.forename: Zhen-Yuan
authors.initials: ZY
authors.lastname: Xu
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D054879:Halogenation; D006859:Hydrogen / Q000737:chemistry; D009566:Nitrates / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry; D013696:Temperature
chemical_list: D000475:Alkenes; D009566:Nitrates; D010165:Palladium; D002244:Carbon; D006859:Hydrogen
keywords: CH activation; alkenes; fluorination; nitrate; room temperature