title: A one-pot, three-component reaction for the synthesis of novel 7-arylbenzo[c]acridine-5,6-diones.
abstract: A one pot domino protocol for an efficient synthesis of 7-arylbenzo[c]acridine-5,6-diones, with a novel nucleus, has been developed by reacting 2-hydroxynaphthalene-1,4-dione, aromatic aldehydes and aromatic amines using environmentally benevolent p-toluene sulphonic acid as a catalyst. An exciting feature of this communication is the reaction mechanism that depends on the reaction solvent.
authors.affiliation: Department of Natural Products, National Institute of Pharmaceutical Education and Research, Sector 67, SAS Nagar, Punjab 160062, India. ipsingh@niper.ac.in ipsingh67@yahoo.com.
authors.forename: Shivani
authors.initials: S
authors.lastname: Mahajan
authors.forename: Sadhika
authors.initials: S
authors.lastname: Khullar
authors.forename: Sanjay K
authors.initials: SK
authors.lastname: Mandal
authors.forename: Inder Pal
authors.initials: IP
authors.lastname: Singh
mesh_terms: D000166:Acridines / Q000138:chemical synthesis*; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D002851:Chromatography, High Pressure Liquid / Q000379:methods
chemical_list: D000166:Acridines