title: Prevalence of renal dysfunction in patients with cirrhosis according to ADQI-IAC working party proposal.
abstract: OBJECTIVE
  A revised classification system for renal dysfunction in patients with cirrhosis was proposed by the Acute Dialysis Quality Initiative and the International Ascites Club Working Group in 2011. The aim of this study was to determine the prevalence of renal dysfunction according to the criteria in this proposal.
  
  
  METHODS
  The medical records of cirrhotic patients who were admitted to Konkuk University Hospital between 2006 and 2010 were reviewed retrospectively. The data obtained at first admission were collected. Acute kidney injury (AKI) and chronic kidney disease (CKD) were defined using the proposed diagnostic criteria of kidney dysfunction in cirrhosis.
  
  
  RESULTS
  Six hundred and forty-three patients were admitted, of whom 190 (29.5%), 273 (42.5%), and 180 (28.0%) were Child-Pugh class A, B, and C, respectively. Eighty-three patients (12.9%) were diagnosed with AKI, the most common cause for which was dehydration (30 patients). Three patients had hepatorenal syndrome type 1 and 26 patients had prerenal-type AKI caused by volume deficiency after variceal bleeding. In addition, 22 patients (3.4%) were diagnosed with CKD, 1 patient with hepatorenal syndrome type 2, and 3 patients (0.5%) with AKI on CKD.
  
  
  CONCLUSIONS
  Both AKI and CKD are common among hospitalized cirrhotic patients, and often occur simultaneously (16.8%). The most common type of renal dysfunction was AKI (12.9%). Diagnosis of type 2 hepatorenal syndrome remains difficult. A prospective cohort study is warranted to evaluate the clinical course in cirrhotic patients with renal dysfunction.
authors.affiliation: Digestive Disease Center, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Yun Jung
authors.initials: YJ
authors.lastname: Choi
authors.affiliation: Digestive Disease Center, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Jeong Han
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Digestive Disease Center, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Ja Kyung
authors.initials: JK
authors.lastname: Koo
authors.affiliation: Digestive Disease Center, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Cho I
authors.initials: CI
authors.lastname: Lee
authors.affiliation: Digestive Disease Center, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Ji Young
authors.initials: JY
authors.lastname: Lee
authors.affiliation: Digestive Disease Center, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Jae Hoon
authors.initials: JH
authors.lastname: Yang
authors.affiliation: Digestive Disease Center, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Soon Young
authors.initials: SY
authors.lastname: Ko
authors.affiliation: Digestive Disease Center, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Won Hyeok
authors.initials: WH
authors.lastname: Choe
authors.affiliation: Digestive Disease Center, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: So Young
authors.initials: SY
authors.lastname: Kwon
authors.affiliation: Digestive Disease Center, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Chang Hong
authors.initials: CH
authors.lastname: Lee
mesh_terms: D058186:Acute Kidney Injury / Q000453:epidemiology* / Q000209:etiology / Q000401:mortality; D000328:Adult; D000368:Aged; D015331:Cohort Studies; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007676:Kidney Failure, Chronic / Q000453:epidemiology* / Q000209:etiology / Q000401:mortality; D008103:Liver Cirrhosis / Q000150:complications / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012720:Severity of Illness Index; D015996:Survival Rate
keywords: Acute kidney injury; Chronic kidney disease; Cirrhosis; Hepatorenal syndrome