title: Effect of a mind-body therapeutic program for infertile women repeating in vitro fertilization treatment on uncertainty, anxiety, and implantation rate.
abstract: OBJECTIVE
  The study aimed to develop a mind-body therapeutic program and evaluate its effects on mitigating uncertainty, anxiety, and implantation rate of second-trial in vitro fertilization (IVF) women.
  
  
  METHODS
  This study employed a nonequivalent control group nonsynchronized design. The conceptual framework and program content were developed from a preliminary survey of eight infertile women and the extensive review of the literature. Program focuses on three uncertainty-induced anxieties in infertile women: cognitive, emotional, and biological responses. To evaluate the effect of the intervention, the infertile women with unknown cause preparing for a second IVF treatment were sampled at convenience (26 experimental and 24 control).
  
  
  RESULTS
  The experimental group in the study showed greater decrease in uncertainty and anxiety in premeasurements and postmeasurements than the control group did. However, no statistically significant differences in the implantation rate between groups were observed.
  
  
  CONCLUSIONS
  This study is meaningful as the first intervention program for alleviating uncertainty and anxiety provided during the IVF treatment process. The positive effects of the mind-body therapeutic program in alleviating both uncertainty and anxiety have direct meaning for clinical applications.
authors.affiliation: Department of Nursing, Namseoul University, Choongnam, South Korea. Electronic address: aprilsea@hanmail.net.
authors.forename: Miok
authors.initials: M
authors.lastname: Kim
authors.affiliation: College of Nursing, Nursing Policy Research Institute, Yonsei University, Seoul, South Korea.
authors.forename: Sue
authors.initials: S
authors.lastname: Kim
authors.affiliation: College of Nursing, Nursing Policy Research Institute, Yonsei University, Seoul, South Korea.
authors.forename: Soon-bok
authors.initials: SB
authors.lastname: Chang
authors.affiliation: College of Nursing, Nursing Policy Research Institute, Yonsei University, Seoul, South Korea.
authors.forename: Ji-Soo
authors.initials: JS
authors.lastname: Yoo
authors.affiliation: Department of Nursing, College of Nursing and Health, Kongju University, Choongnam, South Korea.
authors.forename: Hee Kyung
authors.initials: HK
authors.lastname: Kim
authors.affiliation: Department of Obstetrics and Gynecology, Fertility Center, Cha Gangnam Medical Center, College of Medicine, Cha University, Seoul, South Korea.
authors.forename: Jung Hyun
authors.initials: JH
authors.lastname: Cho
mesh_terms: D000328:Adult; D001007:Anxiety / Q000523:psychology / Q000628:therapy; D016022:Case-Control Studies; D010064:Embryo Implantation; D005260:Female; D005307:Fertilization in Vitro / Q000523:psychology*; D006801:Humans; D007247:Infertility, Female / Q000523:psychology*; D026441:Mind-Body Therapies / Q000379:methods*; D016896:Treatment Outcome; D035501:Uncertainty; D014930:Women / Q000523:psychology*
keywords: anxiety; fertilization in vitro; infertility; mind-body therapies; uncertainty