title: Pre-operative ⁶⁸Ga-DOTANOC somatostatin receptor PET/CT imaging demonstrating multiple synchronous lesions in a patient with head and neck paraganglioma.
abstract: Paragangliomas, or glomus tumors, are neoplasms arising from extra-adrenal chromaffin tissue. They frequently cause symptoms by over-production of catecholamines with known predilection to multicentricity. We describe the case of a patient with bilateral carotid body tumor who underwent a preoperative ⁶⁸Gallium labeled [1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-1-NaI3-Octreotide (⁶⁸Ga-DOTANOC) positron emission tomography/computed tomography (PET/CT) imaging for staging. This is a unique case in which multiple paraganglioma and pheochromocytoma were demonstrated in a single patient using ⁶⁸Ga-DOTANOC PET/CT.
authors.affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: N
authors.initials: N
authors.lastname: Naswa
authors.affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: S
authors.initials: S
authors.lastname: Karunanithi
authors.affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: P
authors.initials: P
authors.lastname: Sharma
authors.affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: R
authors.initials: R
authors.lastname: Soundararajan
authors.affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: C
authors.initials: C
authors.lastname: Bal
authors.affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India. Electronic address: rkphulia@hotmail.com.
authors.forename: R
authors.initials: R
authors.lastname: Kumar
mesh_terms: D000008:Abdominal Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging; D000310:Adrenal Gland Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging*; D002345:Carotid Body Tumor / Q000737:chemistry / Q000000981:diagnostic imaging*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008479:Mediastinal Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging; D008875:Middle Aged; D064847:Multimodal Imaging; D009363:Neoplasm Proteins / Q000032:analysis; D009378:Neoplasms, Multiple Primary / Q000737:chemistry / Q000000981:diagnostic imaging*; D009942:Organometallic Compounds / Q000032:analysis*; D010235:Paraganglioma / Q000737:chemistry / Q000000981:diagnostic imaging*; D010673:Pheochromocytoma / Q000737:chemistry / Q000000981:diagnostic imaging*; D000072078:Positron Emission Tomography Computed Tomography; D011300:Preoperative Care; D019275:Radiopharmaceuticals / Q000032:analysis*; D017481:Receptors, Somatostatin / Q000032:analysis; D012680:Sensitivity and Specificity; D051598:Whole Body Imaging
chemical_list: C504894:68Ga-DOTANOC; D009363:Neoplasm Proteins; D009942:Organometallic Compounds; D019275:Radiopharmaceuticals; D017481:Receptors, Somatostatin
keywords: (68)Ga-DOTANOC; (68)Ga-tetraaza ciclododecano ácido tetraacético-Nal (3)-octreótido; (68)Ga-tetraazacyclododecane tetraacetic acid-Nal(3)-octreotide; Carotid body tumor; Gammagrafía; PET/CT; PET/TC; Paraganglioma; Radionuclide imaging; Tumor del cuerpo carotídeo