title: Vimentin positive acantholytic penile squamous cell carcinoma with rhabdoid features.
abstract: Acantholytic variant of penile squamous cell carcinoma (SCC) is an exceedingly rare and associated with bad prognosis. Histologically it mimics angiosarcoma due to pseudovascular spaces. Vimentin immunopositivity in such cases represent epithelial to mesenchymal transition manifested by cellular discohesion. We describe a case of vimentin positive acantholytic penile SCC in a 55-year-old patient.
authors.forename: Ramesh Y
authors.initials: RY
authors.lastname: Chavan
authors.affiliation: Department of Pathology and Surgery, KLE University's Jawaharlal Nehru Medical College, Belgaum, Karnataka, India.
authors.forename: Akshay
authors.initials: A
authors.lastname: Bali
authors.forename: K S
authors.initials: KS
authors.lastname: Savita
authors.forename: J V
authors.initials: JV
authors.lastname: Chethan
mesh_terms: D000051:Acantholysis / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010412:Penile Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D014746:Vimentin / Q000378:metabolism*
chemical_list: D014746:Vimentin