title: Map transfer from the thalamus to the neocortex: inputs from the barrel field.
abstract: Sensory perception relies on the formation of stereotyped maps inside the brain. This feature is particularly well illustrated in the mammalian neocortex, which is subdivided into distinct cortical sensory areas that comprise topological maps, such as the somatosensory homunculus in humans or the barrel field of the large whiskers in rodents. How somatosensory maps are formed and relayed into the neocortex remain essential questions in developmental neuroscience. Here, we will present our current knowledge on whisker map transfer in the mouse model, with the goal of linking embryonic and postnatal studies into a comprehensive framework.
authors.affiliation: Ecole Normale Supérieure, Institut de Biologie de l'ENS, IBENS, 46 rue d'Ulm, Paris F-75005, France; Inserm, U1024, Paris F-75005, France; CNRS, UMR 8197, Paris F-75005, France. Electronic address: lokmane@biologie.ens.fr.
authors.forename: Ludmilla
authors.initials: L
authors.lastname: Lokmane
authors.affiliation: Ecole Normale Supérieure, Institut de Biologie de l'ENS, IBENS, 46 rue d'Ulm, Paris F-75005, France; Inserm, U1024, Paris F-75005, France; CNRS, UMR 8197, Paris F-75005, France. Electronic address: garel@biologie.ens.fr.
authors.forename: Sonia
authors.initials: S
authors.lastname: Garel
mesh_terms: D000818:Animals; D001931:Brain Mapping; D051379:Mice; D008959:Models, Neurological; D019579:Neocortex / Q000033:anatomy & histology / Q000196:embryology / Q000502:physiology*; D009434:Neural Pathways / Q000033:anatomy & histology / Q000196:embryology / Q000502:physiology; D013003:Somatosensory Cortex / Q000033:anatomy & histology / Q000196:embryology / Q000502:physiology*; D013788:Thalamus / Q000033:anatomy & histology / Q000196:embryology / Q000502:physiology*; D014738:Vibrissae / Q000294:innervation / Q000502:physiology
keywords: Axonal ordering; Axonal plasticity; Barrel field formation; Cortical regionalization; Thalamocortical axons