title: Poor sleep quality measured by polysomnography in non-obese asthmatic children with or without moderate to severe obstructive sleep apnea.
abstract: BACKGROUND
  The co-effect of asthma and obstructive sleep apnea (OSA) on sleep quality among children remained unclear.
  
  
  OBJECTIVE
  To compare sleep quality and emotional/behavioral problems among asthmatic and non-asthmatic children with or without moderate to severe obstructive sleep apnea.
  
  
  METHODS
  An AHI-range-matched BMI-range-matched cross-sectional design was used to examine polysomnographic evaluation and emotional/behavioral problems in 102 non-obese children aged between 6 and 12 years old, categorized as with or without asthma and sleep disordered breathing.
  
  
  RESULTS
  Asthmatic children in AHI ≤ 5/h group revealed a significantly longer sleep latency, a greater leg movement index (LMI), and a lower ratio of slow wave sleep compared with non-asthmatic AHI ≤ 5/h group. Compared with non-asthmatic AHI > 5/h group, asthmatic children displayed a higher ratio of REM sleep, sleep stage 1 and 2, a lower ratio of slow wave sleep, as well as a greater respiratory arousal index and LMI. There was no significant difference in emotional/behavior problems among groups.
  
  
  CONCLUSIONS
  Sleep disturbance exists in asthmatic children with or without moderate to severe obstructive sleep apnea. Non-obese asthmatic children had less slow wave sleep compared with non-asthmatic children. We might recommend that sleep quality could be noticed and evaluated in children with asthma.
authors.affiliation: Graduate Institute of clinical medical science, China Medical University, Taichung, Taiwan; School of Nursing, China Medical University, Taichung, Taiwan.
authors.forename: Yu-Kuei
authors.initials: YK
authors.lastname: Teng
authors.affiliation: School of Nursing, National Defense Medical Center, Taiwan.
authors.forename: Li-Chi
authors.initials: LC
authors.lastname: Chiang
authors.affiliation: Department of Pediatrics, Chung Shan Medical University Hospital Taichung, Taiwan; School of Medicine, Chung Shan Medical University Taichung, Taiwan.
authors.forename: Ko-Huang
authors.initials: KH
authors.lastname: Lue
authors.affiliation: Center of Sleep Medicine, Chung-Shan Medical University Hospital, Chung-Shan Medical University, Taichung, Taiwan.
authors.forename: Shen-Wen
authors.initials: SW
authors.lastname: Chang
authors.affiliation: Department of Public Health, Chung-Shan Medical University, Taichung, Taiwan.
authors.forename: Lee
authors.initials: L
authors.lastname: Wang
authors.affiliation: Department of Foreign Languages and Literature, Asia University, Taichung, Taiwan.
authors.forename: Shu-Ping
authors.initials: SP
authors.lastname: Lee
authors.affiliation: Center of Sleep Medicine, Chung-Shan Medical University Hospital, Chung-Shan Medical University, Taichung, Taiwan; Department of Physical Medicine and Rehabilitation, Chung-Shan Medical University Hospital, Chung-Shan Medical University, Taichung, Taiwan.
authors.forename: Hua
authors.initials: H
authors.lastname: Ting
authors.affiliation: Graduate Institute of clinical medical science, China Medical University, Taichung, Taiwan; Department of Physical Therapy, Graduate Institute of Rehabilitation Science, China Medical University, Taichung, Taiwan; Department of Healthcare Administration, Asia University, Taichung, Taiwan. Electronic address: shinda@mail.cmu.edu.tw.
authors.forename: Shin-Da
authors.initials: SD
authors.lastname: Lee
mesh_terms: D000342:Affective Symptoms / Q000175:diagnosis; D001249:Asthma / Q000175:diagnosis*; D001835:Body Weight; D002648:Child; D002653:Child Behavior Disorders / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D017286:Polysomnography; D012016:Reference Values; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis*; D012893:Sleep Wake Disorders / Q000175:diagnosis*
keywords: Asthma; Child; Obstructive sleep apnea; Polysomnography; Sleep