title: Liposarcoma: a soft tissue tumor with many presentations.
abstract: Liposarcoma is an uncommon connective tissue tumor arising from lipoblast cells. The lesion is located in body soft parts and rarely arises from the bones. The tumors are variable in presentation ranging from benign well-differentiated tumors to myxoid and round cell-dedifferentiated and pleomorphic forms which can present with metastases. The lesions are most often treated by surgical resection. Chemotherapy and radiation may be added to the treatment of the more malignant variants with some success.
authors.affiliation: Departments of Orthopaedics, Pathology, Radiation Oncology, Hematology/Oncology, Massachusetts General Hospital, Boston, MA, USA, HMANKIN@PARTNERS.ORG.
authors.forename: H J
authors.initials: HJ
authors.lastname: Mankin
authors.forename: K P
authors.initials: KP
authors.lastname: Mankin
authors.forename: D C
authors.initials: DC
authors.lastname: Harmon
mesh_terms: D006801:Humans; D008080:Liposarcoma / Q000175:diagnosis* / Q000628:therapy; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000628:therapy; D016019:Survival Analysis