title: Characteristics of Hodgkin lymphoma in a defined group of Iranian pediatric patients.
abstract: This study was conducted to describe the characteristics of Hodgkin lymphoma in Iranian children. In a referral center for pediatric oncology (Mofid Hospital) in Tehran, patient data over a 10-year period were retrieved and recorded accordingly. Among 82 cases, 73.2% were male, 26.8% were female, and 70.7% were 5-9 years old. About 40% of patients were in stage III and 42.7% had systemic signs. Cervical nodes were commonly involved (91.5%). The most frequent histological subtype was mixed cellularity. The main hematological features were anemia (47.6%), lymphopenia (20.7%), and eosinophilia (8.7%). Survival rate was 72%, and 8.4% of patients were deceased. A 3% recurrence rate was observed in our patients. A significant relationship was found between the stage of disease and systemic signs (P<0.0005, χ2). Despite diagnosis of Hodgkin lymphoma in many children in Iran being made in higher stages, the mortality rate is relatively low.
authors.affiliation: Department of Oral Medicine, Faculty of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran E-mail : hamedmortazavi2013@gmail.com.
authors.forename: Maryam
authors.initials: M
authors.lastname: Baharvand
authors.forename: Hamed
authors.initials: H
authors.lastname: Mortazavi
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006689:Hodgkin Disease / Q000401:mortality / Q000473:pathology*; D006801:Humans; D007492:Iran; D008297:Male; D015996:Survival Rate