title: Life satisfaction in adult survivors of childhood brain tumors.
abstract: Adult survivors of childhood brain tumors experience multiple, significant, lifelong deficits as a consequence of their malignancy and therapy. Current survivorship literature documents the substantial impact such impairments have on survivors' physical health and quality of life. Psychosocial reports detail educational, cognitive, and emotional limitations characterizing survivors as especially fragile, often incompetent, and unreliable in evaluating their circumstances. Anecdotal data suggest some survivors report life experiences similar to those of healthy controls. The aim of our investigation was to determine whether life satisfaction in adult survivors of childhood brain tumors differs from that of healthy controls and to identify potential predictors of life satisfaction in survivors. This cross-sectional study compared 78 brain tumor survivors with population-based matched controls. Chi-square tests, t tests, and linear regression models were used to investigate patterns of life satisfaction and identify potential correlates. Results indicated that life satisfaction of adult survivors of childhood brain tumors was similar to that of healthy controls. Survivors' general health expectations emerged as the primary correlate of life satisfaction. Understanding life satisfaction as an important variable will optimize the design of strategies to enhance participation in follow-up care, reduce suffering, and optimize quality of life in this vulnerable population.
authors.affiliation: St. Jude Children's Research Hospital, Memphis, TN, USA debbie.crom@stjude.org.
authors.forename: Deborah B
authors.initials: DB
authors.lastname: Crom
authors.affiliation: St. Jude Children's Research Hospital, Memphis, TN, USA.
authors.forename: Zhenghong
authors.initials: Z
authors.lastname: Li
authors.affiliation: St. Jude Children's Research Hospital, Memphis, TN, USA.
authors.forename: Tara M
authors.initials: TM
authors.lastname: Brinkman
authors.affiliation: St. Jude Children's Research Hospital, Memphis, TN, USA.
authors.forename: Melissa M
authors.initials: MM
authors.lastname: Hudson
authors.affiliation: St. Jude Children's Research Hospital, Memphis, TN, USA.
authors.forename: Gregory T
authors.initials: GT
authors.lastname: Armstrong
authors.affiliation: University of Minnesota, Minneapolis, MN, USA.
authors.forename: Joseph
authors.initials: J
authors.lastname: Neglia
authors.affiliation: St. Jude Children's Research Hospital, Memphis, TN, USA.
authors.forename: Kirsten K
authors.initials: KK
authors.lastname: Ness
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000523:psychology*; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004644:Emotions; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010549:Personal Satisfaction; D011788:Quality of Life / Q000523:psychology*; D017741:Survivors / Q000523:psychology*; D014481:United States; D055815:Young Adult
keywords: life satisfaction; pediatric brain tumors; quality of life; survivorship