title: The Mre11/Rad50/Nbs1 complex: recent insights into catalytic activities and ATP-driven conformational changes.
authors.affiliation: The Howard Hughes Medical Institute, The Department of Molecular Biosciences, The Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA. Electronic address: tpaull@utexas.edu.
authors.forename: Tanya T
authors.initials: TT
authors.lastname: Paull
authors.affiliation: The Howard Hughes Medical Institute, The Department of Molecular Biosciences, The Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA.
authors.forename: Rajashree A
authors.initials: RA
authors.lastname: Deshpande
mesh_terms: D017766:Acid Anhydride Hydrolases; D000255:Adenosine Triphosphate / Q000494:pharmacology*; D002384:Catalysis; D018797:Cell Cycle Proteins / Q000737:chemistry* / Q000378:metabolism; D045643:DNA Repair Enzymes / Q000737:chemistry* / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D000076228:MRE11 Homologue Protein; D009687:Nuclear Proteins / Q000737:chemistry* / Q000378:metabolism; D011487:Protein Conformation / Q000187:drug effects*
chemical_list: D018797:Cell Cycle Proteins; D004268:DNA-Binding Proteins; C121766:MRE11 protein, human; C112156:NBN protein, human; D009687:Nuclear Proteins; D000255:Adenosine Triphosphate; D000076228:MRE11 Homologue Protein; D017766:Acid Anhydride Hydrolases; C112158:RAD50 protein, human; D045643:DNA Repair Enzymes
keywords: DNA double-strand break repair; Mre11; Nbs1; Rad50