title: Bipotent or Oligopotent? A macrophage and DC progenitor revisited.
abstract: Macrophage and dendritic cell (DC) progenitors (MDPs) produce macrophages and DCs but not other hematopoietic lineages. In this issue of Immunity, Sathe et al. (2014) show that isolated MDP populations hardly contain such bipotent progenitors at clonal levels, arguing against the existence of MDPs.
authors.affiliation: Department of Biodefense Research, Medical Research Institute, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Onai
authors.affiliation: Department of Biodefense Research, Medical Research Institute, Tokyo Medical and Dental University, Tokyo 113-8510, Japan. Electronic address: ohteki.bre@mri.tmd.ac.jp.
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Ohteki
mesh_terms: D000818:Animals; D019070:Cell Lineage / Q000276:immunology*; D003713:Dendritic Cells / Q000166:cytology*; D008221:Lymphoid Tissue / Q000166:cytology*; D008264:Macrophages / Q000166:cytology*; D055017:Monocyte-Macrophage Precursor Cells / Q000166:cytology*