title: [Clinical reseach of early laryngocarcinoma treatment by carbon dioxide laser microsurgery].
abstract: OBJECTIVE
  To define the oncologic efficacy of transoral endoscopic CO2 laser surgery in early glottic carci noma.
  
  
  METHODS
  A retrospective study of 112 patients with laryngocarcinoma treated. Surgical treatment included endoscopic CO2 laser cordectomies according to the classification of the European Laryngological Society. After the patients were given the general anesthesia and oral intubation, the tumors in the study group were resected along the margin of the tumor under larynscope, and the safety margin was reserved as 3-5 mm. All the patients were followed-up for 12-62 months.
  
  
  RESULTS
  Eight relapses were detected in 112 cases of glottic laryngeal carcinoma after CO2 laser surgery. The local recurernce rate was 7.14% (8/112),of the rate for T1a, T1b and T2 were 0.89%, 0.89% and 5.04% respectively, with significant differences among groups (chi2 = 5.306, P < 0.01) . The rate of local recurrence rate of anterior commissure involvement was 7.14% and that was 7.14% when this site was not compromised by the tumor, which has no statistically significant differences (chi2 = 0.000, P > 0.01).
  
  
  CONCLUSIONS
  According to our reaserch, endoscopic CO2 laser sur gery is an effective treatment for early laryngocarcinoma.
authors.forename: Fayao
authors.initials: F
authors.lastname: He
authors.forename: Yuejian
authors.initials: Y
authors.lastname: Wang
authors.forename: Weixiong
authors.initials: W
authors.lastname: Chen
authors.forename: Zhaofeng
authors.initials: Z
authors.lastname: Zhu
authors.forename: Yong
authors.initials: Y
authors.lastname: Zeng
authors.forename: Jianli
authors.initials: J
authors.lastname: Zhang
authors.forename: Sucheng
authors.initials: S
authors.lastname: Tang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002245:Carbon Dioxide / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000601:surgery*; D053685:Laser Therapy; D054020:Lasers, Gas / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D002245:Carbon Dioxide