title: Natamycin based sol-gel antimicrobial coatings on polylactic acid films for food packaging.
abstract: In this work a comprehensive study on a new active packaging obtained by a hybrid organic-inorganic coating with antimicrobial properties was carried out. The packaging system based on polylactic acid was realised by sol-gel processing, employing tetraethoxysilane as a precursor of the inorganic phase and polyvinyl alcohol as the organic component, and incorporating natamycin as the active agent. Films with different organic-inorganic ratios (in a range between 1:19 and 1:4) were prepared, and the amount of antimycotic entrapped was found to be modulated by the sol composition, and was between 0.18 and 0.25mg/dm(2). FTIR microspectroscopic measurements were used to characterise the prepared coatings. The antifungal properties of the films were investigated against mould growth on the surface of commercial semi-soft cheese. The release of natamycin from the films to ethanol 50% (v/v) was studied by means of HPLC UV-DAD. The maximal level released was about 0.105 mg/dm(2), which is far below the value allowed by legislation.
authors.affiliation: Department of Chemistry, University of Parma, Parco Area delle Scienze, 17/A, 43124 Parma, Italy.
authors.forename: Claudia
authors.initials: C
authors.lastname: Lantano
authors.affiliation: Department of Chemistry, University of Parma, Parco Area delle Scienze, 17/A, 43124 Parma, Italy; CIPACK, Interdepartmental Center on Packaging, Parco Area delle Scienze, 181/A, 43124 Parma, Italy.
authors.forename: Ilaria
authors.initials: I
authors.lastname: Alfieri
authors.affiliation: Department of Chemistry, University of Parma, Parco Area delle Scienze, 17/A, 43124 Parma, Italy; CIPACK, Interdepartmental Center on Packaging, Parco Area delle Scienze, 181/A, 43124 Parma, Italy.
authors.forename: Antonella
authors.initials: A
authors.lastname: Cavazza
authors.affiliation: Department of Chemistry, University of Parma, Parco Area delle Scienze, 17/A, 43124 Parma, Italy; CIPACK, Interdepartmental Center on Packaging, Parco Area delle Scienze, 181/A, 43124 Parma, Italy. Electronic address: claudio.corradini@unipr.it.
authors.forename: Claudio
authors.initials: C
authors.lastname: Corradini
authors.affiliation: Department of Chemistry, University of Parma, Parco Area delle Scienze, 17/A, 43124 Parma, Italy; CIPACK, Interdepartmental Center on Packaging, Parco Area delle Scienze, 181/A, 43124 Parma, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Lorenzi
authors.affiliation: Department of Chemistry, University of Parma, Parco Area delle Scienze, 17/A, 43124 Parma, Italy; CIPACK, Interdepartmental Center on Packaging, Parco Area delle Scienze, 181/A, 43124 Parma, Italy.
authors.forename: Nicola
authors.initials: N
authors.lastname: Zucchetto
authors.affiliation: Department of Chemistry, University of Parma, Parco Area delle Scienze, 17/A, 43124 Parma, Italy; CIPACK, Interdepartmental Center on Packaging, Parco Area delle Scienze, 181/A, 43124 Parma, Italy.
authors.forename: Angelo
authors.initials: A
authors.lastname: Montenero
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D018857:Food Packaging / Q000379:methods*; D019344:Lactic Acid / Q000737:chemistry*; D010866:Natamycin / Q000627:therapeutic use*; D011091:Polyesters; D011108:Polymers / Q000737:chemistry*; D019904:Polymethyl Methacrylate
chemical_list: D000890:Anti-Infective Agents; D000935:Antifungal Agents; D011091:Polyesters; D011108:Polymers; D019344:Lactic Acid; C033616:poly(lactide); D010866:Natamycin; D019904:Polymethyl Methacrylate
keywords: Antimicrobial active packaging; Cheese; Natamycin; Polylactic acid; Polyvinyl alcohol; Sol–gel