title: Stereoselective construction of a key hydroindole precursor of epidithiodiketopiperazine (ETP) natural products.
abstract: An asymmetric synthetic strategy for constructing the divergent-synthesis monomer of epidithiodiketopiperazine (ETP) natural products has been successfully developed. The functionalized 2,3,3a,4,7,7a-hexahydroindole scaffold was constructed by a diastereoselective inverse electron-demand Diels-Alder (IEDDA) reaction.
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, P. R. China. xfjiang@chem.ecnu.edu.cn.
authors.forename: Minghao
authors.initials: M
authors.lastname: Feng
authors.forename: Xuefeng
authors.initials: X
authors.lastname: Jiang
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D061565:Cycloaddition Reaction; D004583:Electrons; D007211:Indoles / Q000138:chemical synthesis / Q000737:chemistry*; D010879:Piperazines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D001688:Biological Products; D007211:Indoles; D010879:Piperazines; C583251:epidithiodiketopiperazine