title: Intraneural perineurioma affecting multiple nerves: a case report and literature review.
abstract: Intraneural perineurioma is a neoplasm of perineurial cells, corresponding to WHO grade I. We present a case of intraneural perineurioma affecting multiple nerves, which usually involved one or two of major nerve trunks in one patient. We describe the clinical presentation, magnetic resonance (MR) neurography characteristics, and pathological characteristics. The differential diagnosis with other diseases, such as neurofibroma, Schwannomatosis and HNPP, will also be discussed. We also review the literature in efforts to highlight recent studies on intraneural perineurioma and heighten and awareness for the possible presentations of this disorder.
authors.affiliation: Department of Pathology, Peking University Health Science Center Beijing 100191, China ; Department of Pathology, Capital Medical University, Xuanwu Hospital Beijing 100053, China.
authors.forename: Lei-Ming
authors.initials: LM
authors.lastname: Wang
authors.affiliation: Department of Pathology, Peking University Health Science Center Beijing 100191, China.
authors.forename: Yan-Feng
authors.initials: YF
authors.lastname: Zhong
authors.affiliation: Department of Pathology, Peking University Health Science Center Beijing 100191, China.
authors.forename: Dan-Feng
authors.initials: DF
authors.lastname: Zheng
authors.affiliation: Department of Neurology, Peking University Third Hospital Beijing 100191, China.
authors.forename: A-Ping
authors.initials: AP
authors.lastname: Sun
authors.affiliation: Department of Neurology, Peking University Third Hospital Beijing 100191, China.
authors.forename: Ying-Shuang
authors.initials: YS
authors.lastname: Zhang
authors.affiliation: Department of Pathology, Peking University Health Science Center Beijing 100191, China.
authors.forename: Rong-Fang
authors.initials: RF
authors.lastname: Dong
authors.affiliation: Department of Pathology, Peking University Health Science Center Beijing 100191, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Pan
mesh_terms: D001176:Arthrogryposis / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D015417:Hereditary Sensory and Motor Neuropathy / Q000175:diagnosis; D006801:Humans; D018317:Nerve Sheath Neoplasms / Q000473:pathology*; D009442:Neurilemmoma / Q000175:diagnosis; D009455:Neurofibroma / Q000175:diagnosis; D017253:Neurofibromatoses / Q000175:diagnosis; D010524:Peripheral Nervous System Neoplasms / Q000473:pathology*; D012878:Skin Neoplasms / Q000175:diagnosis; D055815:Young Adult
keywords: Intraneural perineurioma; MR; neuropathology; pseudo-onion bulbs