title: Biology of stem cells: an overview.
abstract: Stem cells are defined as precursor cells that have the capacity to self-renew and to generate multiple mature cell types. Only after collecting and culturing tissues is it possible to classify cells according to this operational concept. This difficulty in identifying stem cellsin situ, without any manipulation, limits the understanding of their true nature. This review aims at presenting, to health professionals interested in this area, an overview on the biology of embryonic and adult stem cells, and their therapeutic potential.
authors.affiliation: Department of Genetics, Universidade Federal do Rio Grande do Sul , Porto Alegre, Brazil.
authors.forename: Pedro C
authors.initials: PC
authors.lastname: Chagastelles
authors.affiliation: Department of Genetics, Universidade Federal do Rio Grande do Sul , Porto Alegre, Brazil ; Postgraduation Program in Genetic and Molecular Diagnosis, Universidade Luterana do Brasil , Canoas, Brazil.
authors.forename: Nance B
authors.initials: NB
authors.lastname: Nardi
keywords: adult stem cells; biological characteristics; cell therapy; embryonic stem cells; human diseases