title: Lipophilic cationic porphyrins as photodynamic sensitisers-Synthesis and structure-activity relationships.
abstract: A convenient synthesis of a range of phosphorous and nitrogen centred lipophilic cationic porphyrins is described. In vitro assays for photodynamic activity against human colorectal adenocarcinoma cells (HT-29) reveal significant differences based on substituents around the cation centres.
authors.affiliation: Department of Chemistry, University of Hull, Kingston-upon-Hull, East Yorkshire HU6 7RX, UK.
authors.forename: Robert
authors.initials: R
authors.lastname: Hudson
authors.forename: Huguette
authors.initials: H
authors.lastname: Savoie
authors.forename: Ross W
authors.initials: RW
authors.lastname: Boyle