title: Connecting model species to nature: predator-induced long-term sensitization in Aplysia californica.
abstract: Previous research on sensitization in Aplysia was based entirely on unnatural noxious stimuli, usually electric shock, until our laboratory found that a natural noxious stimulus, a single sublethal lobster attack, causes short-term sensitization. We here extend that finding by demonstrating that multiple lobster attacks induce long-term sensitization (≥24 h) as well as similar, although not identical, neuronal correlates as observed after electric shock. Together these findings establish long- and short-term sensitization caused by sublethal predator attack as a natural equivalent to sensitization caused by artificial stimuli.
authors.affiliation: Schmid College of Science, Chapman University, Orange, California 92866, USA.
authors.forename: Maria J
authors.initials: MJ
authors.lastname: Mason
authors.affiliation: Schmid College of Science, Chapman University, Orange, California 92866, USA.
authors.forename: Amanda J
authors.initials: AJ
authors.lastname: Watkins
authors.affiliation: Schmid College of Science, Chapman University, Orange, California 92866, USA.
authors.forename: Jordann
authors.initials: J
authors.lastname: Wakabayashi
authors.affiliation: Schmid College of Science, Chapman University, Orange, California 92866, USA.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Buechler
authors.affiliation: Schmid College of Science, Chapman University, Orange, California 92866, USA.
authors.forename: Christine
authors.initials: C
authors.lastname: Pepino
authors.affiliation: Schmid College of Science, Chapman University, Orange, California 92866, USA.
authors.forename: Michelle
authors.initials: M
authors.lastname: Brown
authors.affiliation: Schmid College of Science, Chapman University, Orange, California 92866, USA wwright@chapman.edu.
authors.forename: William G
authors.initials: WG
authors.lastname: Wright
mesh_terms: D000818:Animals; D001048:Aplysia / Q000502:physiology*; D004597:Electroshock; D017952:Ganglia, Invertebrate / Q000502:physiology; D008564:Membrane Potentials; D008839:Microelectrodes; D009046:Motor Neurons / Q000502:physiology; D009473:Neuronal Plasticity; D033521:Palinuridae; D010812:Physical Stimulation; D011235:Predatory Behavior; D011897:Random Allocation; D012018:Reflex / Q000502:physiology; D013569:Synapses / Q000502:physiology; D014741:Video Recording