title: Vaccine allergy.
abstract: Overdiagnosis of vaccine allergy is considered a major public health problem. This article discusses the different types of allergic reactions after immunization based on the timing (immediate vs nonimmediate) and the extent of the reaction (local vs systemic). The vaccine components potentially responsible for an allergic reaction are discussed, as well as the management of patients with a history of reaction to a specific vaccine and those with a history of allergy to one of the vaccine components.
authors.affiliation: Department of Pediatrics, University Hospitals of Geneva and Medical School, University of Geneva, Geneva, Switzerland. Electronic address: Jean-Christoph.Caubet@hucge.ch.
authors.forename: Jean-Christoph
authors.initials: JC
authors.lastname: Caubet
authors.affiliation: Pulmonology & Allergology Service, Department of Pediatrics, Sick Children's Hospital, Paris, France.
authors.forename: Claude
authors.initials: C
authors.lastname: Ponvert
mesh_terms: D019468:Disease Management; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control*; D012307:Risk Factors; D014612:Vaccines / Q000009:adverse effects* / Q000145:classification
chemical_list: D014612:Vaccines
keywords: Children; Egg; Gelatin; Hypersensitivity; Toxoids; Vaccine allergy; Vaccine components