title: Oral health-related quality of life of patients with oral lichen planus, oral leukoplakia, or oral squamous cell carcinoma.
abstract: OBJECTIVE
  To compare oral health-related quality of life (OHRQoL) of patients with oral lichen planus (OLP), oral leukoplakia (OL), or oral squamous cell carcinoma (OSCC).
  
  
  METHODS
  Seventy-three patients with OLP, 44 with OL, and 37 with OSCC participated in this prospective study. The German version of the 14-item Oral Health Impact Profile (OHIP-G 14) was used to measure OHRQoL. Descriptive statistics and multivariate analysis of clinical forms, age, gender, alcohol consumption, and smoking habits were evaluated.
  
  
  RESULTS
  No association to cumulative OHIP-14 score (P = .086) among the 3 groups was found. However, patients with OLP showed a higher "physical pain" score and a lower "social disability" score (P = .026) than patients with OSCC, followed by patients with OL. Women with OLP had a lower OHRQoL than men. After differentiation of clinical forms of OLP (symptomatic vs asymptomatic), an impact on these patients' OHRQoL in the dimensions "physical pain" and "physical disability" was found.
  
  
  CONCLUSIONS
  Patients with OLP or OSCC and high OHIP-G 14 scores reported physical pain, which emphasizes the need for physical therapy. For improved OHRQoL, patients with symptomatic forms of OLP would gain more from a treatment compared with those with asymptomatic forms. In contrast, patients with asymptomatic OLP or OL and thus with a minimal impact on their OHRQoL might be at risk of delayed consultation, diagnosis, and treatment of their condition.
authors.affiliation: Resident, Department of Oral and Maxillofacial Surgery, University Medical Center, Mainz, Germany. Electronic address: jkarbach@uni-mainz.de.
authors.forename: Julia
authors.initials: J
authors.lastname: Karbach
authors.affiliation: Professor, Department of Oral and Maxillofacial Surgery, University Medical Center, Mainz, Germany.
authors.forename: Bilal
authors.initials: B
authors.lastname: Al-Nawas
authors.affiliation: Consultant, Department of Oral and Maxillofacial Surgery, University Medical Center, Mainz, Germany.
authors.forename: Maximilian
authors.initials: M
authors.lastname: Moergel
authors.affiliation: Professor, Department of Oral Surgery, University Medical Center, Mainz, Germany.
authors.forename: Monika
authors.initials: M
authors.lastname: Daubländer
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007972:Leukoplakia, Oral / Q000503:physiopathology*; D017676:Lichen Planus, Oral / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000503:physiopathology*; D009909:Oral Health; D011788:Quality of Life