title: Brief report: independent validation of autism spectrum disorder case status in the Utah Autism and Developmental Disabilities Monitoring (ADDM) Network Site.
abstract: An independent validation was conducted of the Utah Autism and Developmental Disabilities Monitoring Network's (UT-ADDM) classification of children with autism spectrum disorder (ASD). UT-ADDM final case status (n = 90) was compared with final case status as determined by independent external expert reviewers (EERs). Inter-rater reliability (ICC = 0.84), specificity [0.83 (95 % CI 0.74-0.90)], and sensitivity [0.99 (95 % CI 0.96-1.00)] were high for ASD case versus non-case classification between UT-ADDM and EER. At least one EER disagreed with UT-ADDM on ASD final case status on nine out of 30 records; however, all three EERs disagreed with UT-ADDM for only one record. Findings based on limited data suggest that children with ASD as identified by UT-ADDM are consistently classified as ASD cases by independent autism experts.
authors.affiliation: Department of Psychiatry, University of Utah, 650 Komas Drive Suite 206, Salt Lake City, UT, 84108, USA, amanda.bakian@hsc.utah.edu.
authors.forename: Amanda V
authors.initials: AV
authors.lastname: Bakian
authors.forename: Deborah A
authors.initials: DA
authors.lastname: Bilder
authors.forename: Paul S
authors.initials: PS
authors.lastname: Carbone
authors.forename: Tyler D
authors.initials: TD
authors.lastname: Hunt
authors.forename: Brent
authors.initials: B
authors.lastname: Petersen
authors.forename: Catherine E
authors.initials: CE
authors.lastname: Rice
mesh_terms: D002648:Child; D002659:Child Development Disorders, Pervasive / Q000175:diagnosis* / Q000453:epidemiology; D002658:Developmental Disabilities / Q000175:diagnosis* / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D011159:Population Surveillance; D015995:Prevalence; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014589:Utah