title: Physicochemical modifications accompanying UV laser induced surface structures on poly(ethylene terephthalate) and their effect on adhesion of mesenchymal cells.
abstract: This work reports on the formation of different types of structures on the surface of polymer films upon UV laser irradiation. Poly(ethylene terephthalate) was irradiated with nanosecond UV pulses at 193 and 266 nm. The polarization of the laser beam and the irradiation angle of incidence were varied, giving rise to laser induced surface structures with different shapes and periodicities. The irradiated surfaces were topographically characterized by atomic force microscopy and the chemical modifications induced by laser irradiation were inspected via micro-Raman and fluorescence spectroscopies. Contact angle measurements were performed with different liquids, and the results evaluated in terms of surface free energy components. Finally, in order to test the influence of surface properties for a potential application, the modified surfaces were used for mesenchymal stem cell culture assays and the effect of nanostructure and surface chemistry on cell adhesion was evaluated.
authors.affiliation: Instituto de Química Física Rocasolano IQFR-CSIC, Serrano 119, 28006 Madrid, Spain. e.rebollar@iqfr.csic.es.
authors.forename: Esther
authors.initials: E
authors.lastname: Rebollar
authors.forename: Susana
authors.initials: S
authors.lastname: Pérez
authors.forename: Margarita
authors.initials: M
authors.lastname: Hernández
authors.forename: Concepción
authors.initials: C
authors.lastname: Domingo
authors.forename: Margarita
authors.initials: M
authors.lastname: Martín
authors.forename: Tiberio A
authors.initials: TA
authors.lastname: Ezquerra
authors.forename: Josefa P
authors.initials: JP
authors.lastname: García-Ruiz
authors.forename: Marta
authors.initials: M
authors.lastname: Castillejo
mesh_terms: D000268:Adhesiveness / Q000528:radiation effects; D002448:Cell Adhesion / Q000502:physiology*; D002478:Cells, Cultured; D006801:Humans; D007834:Lasers; D008422:Materials Testing; D059630:Mesenchymal Stem Cells / Q000166:cytology* / Q000502:physiology*; D011093:Polyethylene Terephthalates / Q000737:chemistry* / Q000528:radiation effects*; D011829:Radiation Dosage; D013499:Surface Properties / Q000528:radiation effects; D014466:Ultraviolet Rays
chemical_list: D011093:Polyethylene Terephthalates