title: Established EUS-guided therapeutic interventions.
abstract: Over the three last decades, endosonography ultrasound (EUS) has evolved from a diagnostic tool to an interventional modality through cumulative advances in experience, knowledge, equipment, and devices. EUS-guided therapeutic procedures appear feasible and safe when performed in highly-experienced centers. This review covers the technical aspects, indications, and results of the most commonly performed procedures. Celiac plexus neurolysis and collection drainages are now well-established techniques and considered to be first-line treatments. Biliary and pancreatic EUS-guided drainages are, conversely, more challenging, and there is currently insufficient clinical evidence documenting their superiority over established practice. Well-designed prospective trials are thus needed in order to accurately assess this modality's risks and long-term outcomes compared to radiological or surgical techniques.
authors.affiliation: Hepato‑Gastroenterology Department Cliniques universitaires Saint‑Luc Université catholique de Louvain Brussels, Belgium - pdeprez@uclouvain.be.
authors.forename: J B
authors.initials: JB
authors.lastname: Chevaux
authors.forename: P H
authors.initials: PH
authors.lastname: Deprez
mesh_terms: D018784:Abdominal Abscess / Q000150:complications / Q000209:etiology; D000208:Acute Disease; D000779:Anesthetics, Local / Q000008:administration & dosage*; D001340:Autonomic Nerve Block / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D001659:Biliary Tract / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002447:Celiac Plexus; D004322:Drainage / Q000295:instrumentation / Q000379:methods*; D019160:Endosonography / Q000295:instrumentation / Q000379:methods*; D004867:Equipment Design; D019317:Evidence-Based Medicine; D006801:Humans; D010146:Pain / Q000209:etiology; D059408:Pain Management / Q000379:methods*; D010182:Pancreatic Diseases / Q000150:complications*; D010190:Pancreatic Neoplasms / Q000150:complications; D010195:Pancreatitis / Q000150:complications; D011788:Quality of Life; D018084:Ultrasonography, Interventional / Q000295:instrumentation / Q000379:methods*
chemical_list: D000779:Anesthetics, Local