title: Selective ortho-hydroxylation-defluorination of 2-fluorophenolates with a bis(μ-oxo)dicopper(III) species.
abstract: The bis(μ-oxo)dicopper(III) species [Cu(III) 2 (μ-O)2 (m-XYL(MeAN) )](2+) (1) promotes the electrophilic ortho-hydroxylation-defluorination of 2-fluorophenolates to give the corresponding catechols, a reaction that is not accomplishable with a (η(2) :η(2) -O2 )dicopper(II) complex. Isotopic labeling studies show that the incoming oxygen atom originates from the bis(μ-oxo) unit. Ortho-hydroxylation-defluorination occurs selectively in intramolecular competition with other ortho-substituents such as chlorine or bromine.
authors.affiliation: Grup de Química Bioinorgànica i Supramolecular (QBIS), Institut de Química Computacional i Catàlisi (IQCC), Departament de Química, Universitat de Girona, Campus Montilivi, 17071 Girona (Catalonia) (Spain).
authors.forename: Joan
authors.initials: J
authors.lastname: Serrano-Plana
authors.forename: Isaac
authors.initials: I
authors.lastname: Garcia-Bosch
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Miyake
authors.forename: Miquel
authors.initials: M
authors.lastname: Costas
authors.forename: Anna
authors.initials: A
authors.lastname: Company
keywords: aromatic defluorination; copper; dioxygen; hydroxylation