title: A novel fluorescence probe for estimation of cysteine/histidine in human blood plasma and recognition of endogenous cysteine in live Hct116 cells.
abstract: A new Cu(II)-complex is used as a "Turn-On" luminescence probe for specific detection of endogenous Cys in live Hct116 cells and Cys present in human blood plasma without any interference from other amino acids, especially GSH and Hcy. Difference in the mechanistic pathway for Cys and His recognition is discussed.
authors.affiliation: Organic Chemistry Division, CSIR-National Chemical Laboratory, Pune-411008, India. a.das@ncl.res.in.
authors.forename: Upendar
authors.initials: U
authors.lastname: Reddy G
authors.forename: Hridesh
authors.initials: H
authors.lastname: Agarwalla
authors.forename: Nandaraj
authors.initials: N
authors.lastname: Taye
authors.forename: Suvankar
authors.initials: S
authors.lastname: Ghorai
authors.forename: Samit
authors.initials: S
authors.lastname: Chattopadhyay
authors.forename: Amitava
authors.initials: A
authors.lastname: Das
mesh_terms: D015179:Colorectal Neoplasms / Q000737:chemistry; D056831:Coordination Complexes / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D003545:Cysteine / Q000032:analysis* / Q000097:blood*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D045325:HCT116 Cells; D006639:Histidine / Q000032:analysis* / Q000097:blood*; D006801:Humans; D008163:Luminescent Measurements
chemical_list: D056831:Coordination Complexes; D005456:Fluorescent Dyes; D006639:Histidine; D003300:Copper; D003545:Cysteine