title: Synthesis of Indolyldiketopiperazines with NBS.
abstract: Two series of indolyldiketopiperazines were synthesized starting from methyl 1-substituted-1,2,3,4-tetrahydro-β-carboline-3-carboxylate hydrochlorides via N-bromo-succinimide (NBS) as an important reagent. All eight compounds were characterized by nuclear magnetic resonance (NMR) and elemental analysis. Furthermore, the mechanisms of NBS-reacted rearrangements are also discussed.
authors.affiliation: Key Laboratory of Auxiliary Chemistry & Technology for Chemical Industry, Ministry of Education, Shaanxi University of Science & Technology, Xi'an, China.
authors.forename: Yangmin
authors.initials: Y
authors.lastname: Ma
authors.forename: Decheng
authors.initials: D
authors.lastname: Ren
authors.forename: Hao
authors.initials: H
authors.lastname: Wu
authors.forename: Jin
authors.initials: J
authors.lastname: Zhang
authors.forename: Tingting
authors.initials: T
authors.lastname: Feng
authors.forename: Yanchao
authors.initials: Y
authors.lastname: Li
mesh_terms: D001974:Bromosuccinimide / Q000737:chemistry*; D002243:Carbolines / Q000737:chemistry; D002264:Carboxylic Acids / Q000737:chemistry; D060326:Chemistry Techniques, Synthetic; D015394:Molecular Structure; D010879:Piperazines / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D002243:Carbolines; D002264:Carboxylic Acids; D010879:Piperazines; C009804:tryptoline; D001974:Bromosuccinimide
keywords: N-bromosuccinimide; conjugative effect; indolyldiketopiperazine; rearrangement