title: Spontaneous pneumothorax after intensive chemotherapy in endometrial cancer: a rare complication.
abstract: OBJECTIVE
  Endometrial cancer with hematogenous metastases can be treated with chemotherapy. We present a case of spontaneous pneumothorax that occurred when a solitary pulmonary endometrial metastatic lesion was treated with paclitaxel plus carboplatin.
  
  
  METHODS
  A 38-year-old female had stage II endometrial endometrioid adenocarcinoma. Solitary bilateral pulmonary metastases developed after primary treatment. Complete remission accompanied by a right spontaneous pneumothorax occurred during chemotherapy with paclitaxel plus carboplatin.
  
  
  CONCLUSIONS
  Rapid shrinkage of a pulmonary space-occupying tumor sometimes causes rare but life-threatening spontaneous pneumothoraces. We report the first case of a spontaneous pneumothorax after using paclitaxel plus carboplatin in the treatment of endometrial cancer.
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan; Mackay Medicine, Nursing and Management College, Taipei, Taiwan. Electronic address: cremaster4471@gmail.com.
authors.forename: Jen-Ruei
authors.initials: JR
authors.lastname: Chen
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Yuh-Cheng
authors.initials: YC
authors.lastname: Yang
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016190:Carboplatin / Q000008:administration & dosage; D018269:Carcinoma, Endometrioid / Q000188:drug therapy* / Q000556:secondary; D016889:Endometrial Neoplasms / Q000188:drug therapy* / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary; D017239:Paclitaxel / Q000008:administration & dosage; D011030:Pneumothorax / Q000209:etiology*; D012074:Remission Induction
chemical_list: D016190:Carboplatin; D017239:Paclitaxel
keywords: carboplatin; endometrial cancer; paclitaxel; pulmonary metastases; spontaneous pneumothorax