title: Dietary patterns and breast cancer: a case-control study in women.
abstract: OBJECTIVE
  Since dietary habits have been associated with breast cancer, the tested research hypothesis was the associations between food patterns, as derived through multivariate methods, and breast cancer.
  
  
  METHODS
  In a case-control study, Two-hundred and fifty consecutive, newly diagnosed breast cancer female patients (56 ± 12 years) and 250 one-to-one age-matched, healthy controls were studied. A standardized, validated questionnaire assessing various socio-demographic, clinical, lifestyle, and dietary characteristics was applied through face-to-face interviews. Factor analysis, with principal components method, was applied to extract dietary patterns from 86 foods or food groups consumption reported by the controls.
  
  
  RESULTS
  Three components were derived explaining 43% of the total variation in consumption. Component 1 was characterized by the consumption of potatoes, red meat and its products, poultry and white meat, dairy products, use of margarine/butter in cooking or at the table, consumption of sausages, fried food as well as grilled meat or fish; component 2 was characterized by the consumption of whole grains, fruits, and vegetables; and component 3 was characterized by olive oil and fish consumption. After adjusting for various confounders, components 2 and 3 were favorably associated with the absence of having breast cancer [odds ratio (OR) 0.60, 95% CI 0.47-0.75 and OR 0.81, 95% CI 0.66-0.99, respectively], while component 1 was not significantly associated with the disease.
  
  
  CONCLUSIONS
  Adherence to healthy dietary patterns (including whole grains, fruits, and vegetables, olive oil, and fish) seems to be favorable in not having breast cancer, among middle-aged women.
authors: Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
authors: Niki
authors: N
authors: Mourouti
authors: Christos
authors: C
authors: Papavagelis
authors: Petrini
authors: P
authors: Plytzanopoulou
authors: Meropi
authors: M
authors: Kontogianni
authors: Tonia
authors: T
authors: Vassilakou
authors: Nikolaos
authors: N
authors: Malamos
authors: Athena
authors: A
authors: Linos
authors: Demosthenes
authors: D
authors: Panagiotakos
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D001943:Breast Neoplasms / Q000453:epidemiology*; D016022:Case-Control Studies; D003611:Dairy Products; D004032:Diet; D005247:Feeding Behavior; D005260:Female; D005638:Fruit; D006115:Greece; D006801:Humans; D008019:Life Style; D008875:Middle Aged; D015596:Nutrition Assessment; D000069463:Olive Oil; D010349:Patient Compliance; D012307:Risk Factors; D017747:Seafood; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D014675:Vegetables; D000067348:Whole Grains
chemical_list: D000069463:Olive Oil