title: Calcium and zinc containing bactericidal glass coatings for biomedical metallic substrates.
abstract: The present work presents new bactericidal coatings, based on two families of non-toxic, antimicrobial glasses belonging to B2O3-SiO2-Na2O-ZnO and SiO2-Na2O-Al2O3-CaO-B2O3 systems. Free of cracking, single layer direct coatings on different biomedical metallic substrates (titanium alloy, Nb, Ta, and stainless steel) have been developed. Thermal expansion mismatch was adjusted by changing glass composition of the glass type, as well as the firing atmosphere (air or Ar) according to the biomedical metallic substrates. Formation of bubbles in some of the glassy coatings has been rationalized considering the reactions that take place at the different metal/coating interfaces. All the obtained coatings were proven to be strongly antibacterial versus Escherichia coli (>4 log).
authors: Department of Biomaterials and Bioinspired Materials, Institute of Materials Science of Madrid (ICMM-CSIC), Cantoblanco, Madrid 28049, Spain. lesteban@icmm.csic.es.
authors: Leticia
authors: L
authors: Esteban-Tejeda
authors: Nanomaterials and Nanotechnology Research Center (CINN-CSIC)-Universidad de Oviedo (UO) -Principado de Asturias, El Entrego, San Martín del Rey Aurelio 33940, Spain. la.diaz@cinn.es.
authors: Luis A
authors: LA
authors: Díaz
authors: Nanomaterials and Nanotechnology Research Center (CINN-CSIC)-Universidad de Oviedo (UO) -Principado de Asturias, El Entrego, San Martín del Rey Aurelio 33940, Spain. c.prado@cinn.es.
authors: Catuxa
authors: C
authors: Prado
authors: Nanomaterials and Nanotechnology Research Center (CINN-CSIC)-Universidad de Oviedo (UO) -Principado de Asturias, El Entrego, San Martín del Rey Aurelio 33940, Spain. b.cabal@cinn.es.
authors: Belén
authors: B
authors: Cabal
authors: Nanomaterials and Nanotechnology Research Center (CINN-CSIC)-Universidad de Oviedo (UO) -Principado de Asturias, El Entrego, San Martín del Rey Aurelio 33940, Spain. r.torrecillas@cinn.es.
authors: Ramón
authors: R
authors: Torrecillas
authors: Department of Biomaterials and Bioinspired Materials, Institute of Materials Science of Madrid (ICMM-CSIC), Cantoblanco, Madrid 28049, Spain. jsmoya@icmm.csic.es.
authors: José S
authors: JS
authors: Moya
mesh_terms: D000497:Alloys / Q000737:chemistry / Q000494:pharmacology; D002118:Calcium / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000737:chemistry / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D005898:Glass / Q000737:chemistry*; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry; D015032:Zinc / Q000737:chemistry*
chemical_list: D000497:Alloys; D020099:Coated Materials, Biocompatible; D014025:Titanium; D015032:Zinc; D002118:Calcium