title: [The changes in the oxygen saturations in the superior vena cava and the pulmonary artery are not the same during cardiac surgery].
abstract: OBJECTIVE
  To evaluate the changes over time (trend) in sign and magnitude for SSVO2 and SVO2 during and after cardiac surgery.
  
  
  METHODS
  A prospective and observational study was conducted on 34 cardiac surgery patients. Venous blood samples were taken simultaneously from the introductor (SVCO2) and distal (SVO2) port of the pulmonary artery catheter at predefined intervals. Systemic and pulmonary hemodynamic variables were measured at the same time. The trend was calculated as the difference between 2 consecutive measurements (tSO2). Data were processed with ANOVA for multiple comparisons, Pearson correlation coefficient and Bland-Altman analysis.
  
  
  RESULTS
  There was a significant correlation between SVCO2 and tSVO2 (R(2)=0.55), the mean of the differences was 0.36±7.75%, and the limits of agreement ranged from -15.1 to 15.9%. The sign of the trend was similar in 85.1% of the paired data. However, the magnitude of the changes in tSVCO2 and tSVO2 were not always equivalent. Between 0 and 5% of the change in the tSVCO2 was coincident with only 44.7% of the tSVO2. A wide variation was found between both trends when the signs and magnitudes of the changes were taken into account.
  
  
  CONCLUSIONS
  When considering the sign and magnitude, the change over time of central venous O2 saturations were not interchangeable in cardiac surgery patients. Clinical decisions based exclusively on tSVCO2 monitoring should be taken with caution.
authors: Departamento y Cátedra de Anestesiología, Hospital de Clínicas, Universidad de la República, Montevideo, Uruguay.
authors: J A
authors: JA
authors: Riva
authors: Departamento y Cátedra de Anestesiología, Hospital de Clínicas, Universidad de la República, Montevideo, Uruguay. Electronic address: jboucha@hc.edu.uy.
authors: J P
authors: JP
authors: Bouchacourt
authors: Departamento y Cátedra de Anestesiología, Hospital de Clínicas, Universidad de la República, Montevideo, Uruguay.
authors: W E
authors: WE
authors: Kohn
authors: Departamento de Fisiopatología, Hospital de Clínicas, Universidad de la República, Montevideo, Uruguay.
authors: F J
authors: FJ
authors: Hurtado
mesh_terms: D006348:Cardiac Surgical Procedures; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D010100:Oxygen / Q000378:metabolism*; D011446:Prospective Studies; D011651:Pulmonary Artery; D014683:Vena Cava, Superior
chemical_list: D010100:Oxygen
keywords: Cardiac surgery; Catéter de arteria pulmonar; Central venous saturation; Cirugía cardíaca; Extracción de oxígeno; Hemodynamic monitoring; Mixed venous saturation; Monitorización hemodinámica; Oxygen extraction ratio; Pulmonary artery catheter; Saturación de sangre venosa mezclada; Saturación de vena cava superior