title: Anticancer effects of fucoidan.
abstract: Recently, there has been an increased interest in the pharmacologically active natural compounds isolated and used for remedies of various kinds of diseases, including cancer. The great deal of interest has been developed to isolate bioactive compounds from marine resources because of their numerous health beneficial effects. Among marine resources, marine algae are valuable sources of structurally diverse bioactive compounds. Fucoidan is a sulfated polysaccharide derived from brown seaweeds and has been used as an ingredient in some dietary supplement products. Fucoidan has various biological activities including antibacterial, antioxidant, anti-inflammatory, anticoagulant, and antitumor activities. So this chapter deals with anticancer effects of fucoidan.
authors: Specialized Graduate School Science and Technology Convergence, Department of Marine Bio Convergence Science, Pukyong National University, Busan, South Korea; Department of Nuclear Medicine, Kyungpook National University School of Medicine, Daegu, South Korea.
authors: Kalimuthu
authors: K
authors: Senthilkumar
authors: Department of Marine-bio Convergence Science, Specialized Graduate School Science and Technology Convergence, Marine Bioprocess Research Center, Pukyong National University, Busan, South Korea. Electronic address: sknkim@pknu.ac.kr.
authors: Se-Kwon
authors: SK
authors: Kim
mesh_terms: D000970:Antineoplastic Agents; D006801:Humans; D015394:Molecular Structure; D009362:Neoplasm Metastasis; D009389:Neovascularization, Pathologic; D000459:Phaeophyceae / Q000737:chemistry*; D011134:Polysaccharides / Q000737:chemistry / Q000502:physiology / Q000627:therapeutic use*; D015398:Signal Transduction
chemical_list: D000970:Antineoplastic Agents; D011134:Polysaccharides; C007789:fucoidan
keywords: Akt; Apoptosis; Cancer; Fucoidan; LMWF; PI3K