title: A meta-analysis of minimally invasive versus conventional sternotomy for aortic valve replacement.
abstract: Minimally invasive aortic valve replacement (AVR) is increasingly used as an alternative to conventional AVR, despite limited randomized evidence available. To assess the evidence base, a systematic search identified 50 comparative studies with a total of 12,786 patients. A meta-analysis demonstrated that minimally invasive AVR is associated with reduced transfusion incidence, intensive care stay, hospitalization, and renal failure, and has a mortality rate that is comparable to conventional AVR. The evidence quality was mostly very low. Given the inadequate statistical power and heterogeneity of available studies, prospective randomized trials are needed to assess the benefits and risks of minimally invasive AVR approaches.
authors: The Collaborative Research (CORE) Group, Macquarie University, Sydney, New South Wales, Australia.
authors: Kevin
authors: K
authors: Phan
authors: The Collaborative Research (CORE) Group, Macquarie University, Sydney, New South Wales, Australia.
authors: Ashleigh
authors: A
authors: Xie
authors: The Collaborative Research (CORE) Group, Macquarie University, Sydney, New South Wales, Australia; Cardiovascular Surgery Department, Sant'Orsola-Malpighi Hospital, Bologna University, Bologna, Italy.
authors: Marco
authors: M
authors: Di Eusanio
authors: The Collaborative Research (CORE) Group, Macquarie University, Sydney, New South Wales, Australia; Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia. Electronic address: tristanyan@annalscts.com.
authors: Tristan D
authors: TD
authors: Yan
mesh_terms: D000368:Aged; D001021:Aortic Valve / Q000601:surgery*; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D007362:Intensive Care Units; D007902:Length of Stay; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D056346:Sternotomy / Q000379:methods*