title: Postoperative stereotactic radiosurgery for resected brain metastasis.
abstract: Despite therapeutic advances in management, the prognosis of patients with brain metastasis remains dismal. Treatment options include surgical resection, whole brain radiation therapy (WBRT), and stereotactic radiosurgery (SRS). Patients who undergo surgical resection typically receive WBRT as adjuvant therapy. However, several studies have demonstrated an association between WBRT and neurotoxicity. Thus, clinicians are increasingly delaying WBRT in favor of postoperative use of SRS. In this review, we will discuss the current literature exploring the efficacy and toxicity of postoperative SRS in the treatment of patients with resected brain metastasis.
authors: Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
authors: Zain
authors: Z
authors: Ahmed
authors: Ehsan
authors: E
authors: Balagamwala
authors: Erin
authors: E
authors: Murphy
authors: Lilyana
authors: L
authors: Angelov
authors: John
authors: J
authors: Suh
authors: Simon
authors: S
authors: Lo
authors: Samuel
authors: S
authors: Chao
mesh_terms: D001921:Brain / Q000473:pathology / Q000601:surgery; D001932:Brain Neoplasms / Q000473:pathology / Q000556:secondary* / Q000601:surgery*; D003131:Combined Modality Therapy; D006801:Humans; D011184:Postoperative Period; D016634:Radiosurgery / Q000009:adverse effects / Q000379:methods*; D016032:Randomized Controlled Trials as Topic; D013997:Time Factors