title: Seropositivity and coinfection of hepatitis B and C among patients seeking hospital care in Islamabad, Pakistan.
abstract: The undertaken study was conducted to find out the seroprevalence and coinfection of HBV and HCV infection among patients seeking hospital care. A total of 845 samples were received at tertiary care hospital of Islamabad and were screened for hepatitis B and C. The ELISA was used to detect antigen for HBV and antibodies for HCV in patient serum. Among 845 collected samples, 255 (30.1%) were seropositive for HBV and HCV. Out of 255 seropositive samples, 45 (5.3%) were positive for HBsAg while 199 (23.5%) were positive for anti-HCV. Among 255, 11 (1.3%) were seropositive for both HBsAg and anti-HCV (coinfection). Among the seropositive male, HBV was more prevalent (23.8%) while female patients had a high incidence of HCV (52.2%). Among the age group variable, HBV, HCV, and coinfection were found to be more common in the age groups of 21-30 (29%) and 30-40 (24%) years. The seropositivity for HBsAg was higher in unmarried individuals (31.2%) while anti-HCV was more prevalent in married individuals (84%). The present study provides the preliminary information about high HCV and HBV prevalence. Findings from the current study will be helpful for the better management and control of viral hepatitis among patients seeking hospital care.
authors: Department of Microbiology, Kohat University of Science and Technology, Kohat 26000, Khyber Pakhtunkhwa, Pakistan.
authors: Jafar
authors: J
authors: Khan
authors: Department of Microbiology, Kohat University of Science and Technology, Kohat 26000, Khyber Pakhtunkhwa, Pakistan.
authors: Mehwish
authors: M
authors: Shafiq
authors: Department of Microbiology, Kohat University of Science and Technology, Kohat 26000, Khyber Pakhtunkhwa, Pakistan.
authors: Sameera
authors: S
authors: Mushtaq
authors: Department of Zoology, Kohat University of Science and Technology, Kohat 26000, Pakistan.
authors: Sultan
authors: S
authors: Ayaz
authors: Department of Chemistry, Government College Ara Khel, FR Kohat 26000, Pakistan.
authors: Riaz
authors: 0000-0002-2860-467X
authors: R
authors: Ullah
authors: Riyadh Community College, King Saud University, Riyadh 11437, Saudi Arabia.
authors: Naser M
authors: NM
authors: AbdEI-Salam
authors: Riyadh Community College, King Saud University, Riyadh 11437, Saudi Arabia.
authors: H
authors: H
authors: Fouad
authors: Department of Chemistry, Sarhad University of Science and Information Technology, Peshawar 25000, Pakistan.
authors: Mohammad Abdul
authors: 0000-0002-4803-5558
authors: MA
authors: Wasim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D060085:Coinfection / Q000150:complications / Q000453:epidemiology* / Q000821:virology; D005260:Female; D006509:Hepatitis B / Q000150:complications* / Q000453:epidemiology* / Q000276:immunology / Q000821:virology; D006514:Hepatitis B Surface Antigens / Q000276:immunology; D006526:Hepatitis C / Q000150:complications* / Q000453:epidemiology* / Q000276:immunology / Q000821:virology; D018937:Hepatitis C Antibodies / Q000276:immunology; D006761:Hospitals / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008875:Middle Aged; D010154:Pakistan / Q000453:epidemiology; D010342:Patient Acceptance of Health Care / Q000706:statistics & numerical data*; D016036:Seroepidemiologic Studies; D055815:Young Adult
chemical_list: D006514:Hepatitis B Surface Antigens; D018937:Hepatitis C Antibodies