title: Role of diet and lifestyle changes in nonalcoholic fatty liver disease.
abstract: Nonalcoholic fatty liver disease (NAFLD) has become one of the most common causes of liver disease worldwide and has been recognized as a major health burden. The prevalence of NAFLD has grown proportionally with the rise in obesity, sedentary lifestyle, unhealthy dietary pattern, and metabolic syndrome. Currently, there is no drug therapy that can be formulated for treating NAFLD. A combination of dietary modifications and increased physical activity remains the mainstay of NAFLD management. It is hard to maintain this mode of management; however, it seems to have significant long-term benefits. Furthermore, NAFLD patients, whether obese or not, should be educated that a healthy diet and physical activity have benefits beyond weight reduction. Further large controlled randomized trials are needed in order to identify the best dietary regimen and physical activity in the management of NAFLD patients. This review highlights the role of diet and lifestyle modifications in the management of NAFLD, and focuses on human studies regarding dietary modifications and physical activity.
authors: William Nseir, Elias Hellou, Department of Internal Medicine, EMMS, The Nazareth Hospital, Nazareth 16100, Israel.
authors: William
authors: W
authors: Nseir
authors: William Nseir, Elias Hellou, Department of Internal Medicine, EMMS, The Nazareth Hospital, Nazareth 16100, Israel.
authors: Elias
authors: E
authors: Hellou
authors: William Nseir, Elias Hellou, Department of Internal Medicine, EMMS, The Nazareth Hospital, Nazareth 16100, Israel.
authors: Nimer
authors: N
authors: Assy
mesh_terms: D031204:Caloric Restriction; D004032:Diet / Q000009:adverse effects*; D050528:Diet, Carbohydrate-Restricted; D018752:Diet, Fat-Restricted; D015444:Exercise; D005247:Feeding Behavior; D006801:Humans; D008019:Life Style; D065626:Non-alcoholic Fatty Liver Disease / Q000175:diagnosis / Q000453:epidemiology / Q000378:metabolism / Q000628:therapy*; D015995:Prevalence; D012307:Risk Factors; D040242:Risk Reduction Behavior; D057185:Sedentary Behavior; D013997:Time Factors; D016896:Treatment Outcome; D015431:Weight Loss
keywords: Aerobic exercise; Caloric restriction; Diet; Lifestyle changes; Management; Nonalcoholic fatty liver disease; Physical activity; Resistance exercise