title: Spasticity and the use of intrathecal baclofen in patients with spinal cord injury.
abstract: Muscle spasms and spasticity constitute a significant problem in patients with spinal cord injury, interfering with rehabilitation and leading to impairments in quality of life in addition to medical complications. Administration of intrathecal baclofen (ITB) is indicated when spasticity continues to produce a clinical disability despite trials of oral treatments and other alternatives in patients who have functional goals and/or pain without contractures. Severe spasticity of spinal origin has been shown to respond dramatically to long-term ITB when used in appropriate patients with spasticity.
authors: Department of Physical Medicine and Rehabilitation, University of Miami, Miller School of Medicine, 1120 Northwest 14th Street, CRB Room 948, Miami, FL 33136, USA. Electronic address: skhurana@med.miami.edu.
authors: Seema R
authors: SR
authors: Khurana
authors: Department of Physical Medicine and Rehabilitation, Jackson Memorial Hospital, University of Miami-Miller School of Medicine, Miami, FL, USA.
authors: Deep S
authors: DS
authors: Garg
mesh_terms: D001418:Baclofen / Q000627:therapeutic use*; D004868:Equipment Failure; D058786:GABA-B Receptor Agonists / Q000627:therapeutic use*; D006801:Humans; D015918:Infusion Pumps, Implantable / Q000009:adverse effects; D060186:Infusions, Spinal / Q000295:instrumentation; D009128:Muscle Spasticity / Q000188:drug therapy* / Q000209:etiology; D018579:Patient Selection; D013119:Spinal Cord Injuries / Q000150:complications*
chemical_list: D058786:GABA-B Receptor Agonists; D001418:Baclofen
keywords: Baclofen; Spasms; Spasticity; Tone