title: Monoclonal hyperglobulinemia in lymphosarcoma in a cockatiel (Nymphicus hollandicus) and a blue and gold macaw (Ara ararauna).
abstract: A 15-yr-old cockatiel (Nymphicus hollandicus) presented with decreased activity and appetite. A presumptive diagnosis of lymphoproliferative disease was made because of a monoclonal band observed on plasma protein electrophoresis. The owner declined further diagnostics or treatment, and the bird died 2 yr later. In a second case, a 4-yr-old blue and gold macaw (Ara ararauna) presented with lethargy and anorexia. Despite supportive treatment, the bird died 7 days later. Blood studies also demonstrated a monoclonal band on plasma protein electrophoresis. The histologic review of tissues from both birds found extensive neoplastic lymphoplasmocytic cells in the liver and supported a diagnosis of lymphosarcoma.
authors: Angela
authors: A
authors: Lennox
authors: Susan
authors: S
authors: Clubb
authors: April
authors: A
authors: Romagnano
authors: Norman H
authors: NH
authors: Altman
authors: Carolyn
authors: C
authors: Cray
mesh_terms: D000818:Animals; D001715:Bird Diseases / Q000175:diagnosis* / Q000628:therapy; D001797:Blood Protein Electrophoresis / Q000379:methods* / Q000662:veterinary; D017809:Fatal Outcome; D006942:Hypergammaglobulinemia / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary; D008099:Liver / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary*; D008297:Male; D010311:Parrots