title: Molecular characterization of DHA-1-producing Klebsiella pneumoniae isolates collected during a 4-year period in an intensive care unit.
abstract: Seventeen Klebsiella pneumoniae isolates producing DHA-1 β-lactamase were collected in an intensive care unit between 2006 and 2010. Molecular analysis revealed the predominance of ST48 and ST1263 clones of K. pneumoniae and the spread of DHA-1-encoding plasmids belonging to incompatibility group IncL/M or IncHI2.
authors: Université Pierre et Marie Curie-Paris 6, Faculté de Médecine, Site Saint-Antoine, Laboratoire de Bactériologie, ER8, Paris, France. Electronic address: compain.fabrice@wanadoo.fr.
authors: Fabrice
authors: F
authors: Compain
authors: Université Pierre et Marie Curie-Paris 6, Faculté de Médecine, Site Saint-Antoine, Laboratoire de Bactériologie, ER8, Paris, France; Laboratoire de Bactériologie, Hôpital Saint-Antoine, Assistance Publique - Hôpitaux de Paris, Paris, France.
authors: Dominique
authors: D
authors: Decré
authors: Service de réanimation, Hôpital Tenon, Assistance Publique - Hôpitaux de Paris, Paris, France.
authors: Jean-Pierre
authors: JP
authors: Fulgencio
authors: Université Pierre et Marie Curie-Paris 6, Faculté de Médecine, Site Saint-Antoine, Laboratoire de Bactériologie, ER8, Paris, France.
authors: Sfia
authors: S
authors: Berraho
authors: Université Pierre et Marie Curie-Paris 6, Faculté de Médecine, Site Saint-Antoine, Laboratoire de Bactériologie, ER8, Paris, France; Laboratoire de Bactériologie, Hôpital Saint-Antoine, Assistance Publique - Hôpitaux de Paris, Paris, France; Laboratoire de Bactériologie, Hôpital Tenon, Assistance Publique - Hôpitaux de Paris, Paris, France.
authors: Guillaume
authors: G
authors: Arlet
authors: Laboratoire de Bactériologie, Hôpital Tenon, Assistance Publique - Hôpitaux de Paris, Paris, France.
authors: Charlotte
authors: C
authors: Verdet
mesh_terms: D002510:Cephalosporinase / Q000235:genetics / Q000378:metabolism*; D029968:Escherichia coli Proteins / Q000235:genetics / Q000378:metabolism*; D005838:Genotype; D006801:Humans; D007362:Intensive Care Units; D007710:Klebsiella Infections / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000145:classification* / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D058889:Molecular Typing; D010957:Plasmids / Q000032:analysis / Q000145:classification
chemical_list: D029968:Escherichia coli Proteins; D002510:Cephalosporinase; C508952:DHA-1 cephalosporinase, E coli
keywords: DHA-1; Klebsiella pneumoniae; Plasmid typing