title: Chronic pancreatitis: A surgical disease? Role of the Frey procedure.
abstract: Although medical treatment and endoscopic interventions are primarily offered to patients with chronic pancreatitis, approximately 40% to 75% will ultimately require surgery during the course of their disease. Although pancreaticoduodenectomy has been considered the standard surgical procedure because of its favorable results on pain control, its high postoperative complication and pancreatic exocrine or/and endocrine dysfunction rates have led to a growing enthusiasm for duodenal preserving pancreatic head resection. The aim of this review is to better understand the rationale underlying of the Frey procedure in chronic pancreatitis and to analyze its outcome. Because of its hybrid nature, combining both resection and drainage, the Frey procedure has been conceptualized based on the pathophysiology of chronic pancreatitis. The short and long-term outcome, especially pain relief and quality of life, are better after the Frey procedure than after any other surgical procedure performed for chronic pancreatitis.
authors: Alexandra Roch, Jérome Teyssedou, Didier Mutter, Jacques Marescaux, Patrick Pessaux, Digestive and Endocrine Surgery, Nouvel Hôpital Civil, University of Strasbourg, 67000 Strabourg, France.
authors: Alexandra
authors: A
authors: Roch
authors: Alexandra Roch, Jérome Teyssedou, Didier Mutter, Jacques Marescaux, Patrick Pessaux, Digestive and Endocrine Surgery, Nouvel Hôpital Civil, University of Strasbourg, 67000 Strabourg, France.
authors: Jérome
authors: J
authors: Teyssedou
authors: Alexandra Roch, Jérome Teyssedou, Didier Mutter, Jacques Marescaux, Patrick Pessaux, Digestive and Endocrine Surgery, Nouvel Hôpital Civil, University of Strasbourg, 67000 Strabourg, France.
authors: Didier
authors: D
authors: Mutter
authors: Alexandra Roch, Jérome Teyssedou, Didier Mutter, Jacques Marescaux, Patrick Pessaux, Digestive and Endocrine Surgery, Nouvel Hôpital Civil, University of Strasbourg, 67000 Strabourg, France.
authors: Jacques
authors: J
authors: Marescaux
authors: Alexandra Roch, Jérome Teyssedou, Didier Mutter, Jacques Marescaux, Patrick Pessaux, Digestive and Endocrine Surgery, Nouvel Hôpital Civil, University of Strasbourg, 67000 Strabourg, France.
authors: Patrick
authors: P
authors: Pessaux
keywords: Chronic pancreatitis; Complication; Frey procedure; Outcome; Surgery