title: Progressive corneal clearance after a DMEK graft partially folded over on itself in a non-fuchs pseudophakic eye.
abstract: OBJECTIVE
  The aim of this study was to report progressive corneal clearance and endothelial cell repopulation after a Descemet membrane endothelial keratoplasty graft that was partially folded over on itself in a pseudophakic patient without endothelial dystrophy.
  
  
  METHODS
  Retrospective case report.
  
  
  RESULTS
  A 75-year-old man without Fuchs dystrophy underwent cataract extraction on his right eye in 2007, and 5 years later, Descemet membrane endothelial keratoplasty was performed for pseudophakic edema in the same eye at another center. On presentation at our institution, a graft that is partially folded over on itself was observed in the right eye, leaving about 2/3 of donor endothelium correctly exposed. The graft was only attached in the lower part of the cornea. We observed progressive clearance of the entire cornea within 7 months with reendothelialization of the entire cornea. Good visual acuity was achieved, with no evidence of recurrent corneal edema.
  
  
  CONCLUSIONS
  Endothelial cell migration and repopulation in the presence of a folded attached endothelium graft may occur, resulting in corneal clearance and improved visual outcome. This could happen in patients with pseudophakic edema without congenital endothelial dystrophy.
authors: Cornea Unit, Institut de Microcirugia Ocular, Universidad Autónoma de Barcelona, Cerdanyola del Vallès, Spain.
authors: Celso D
authors: CD
authors: Ponce de Los Ríos
authors: Oscar
authors: O
authors: Gris
authors: Daniel
authors: D
authors: Elies
authors: Jose L
authors: JL
authors: Güell
mesh_terms: D000086:Acetazolamide / Q000627:therapeutic use; D000368:Aged; D044482:Benzeneacetamides / Q000627:therapeutic use; D002387:Cataract Extraction; D003315:Cornea / Q000502:physiology*; D015715:Corneal Edema / Q000188:drug therapy / Q000601:surgery*; D057111:Descemet Stripping Endothelial Keratoplasty; D004728:Endothelium, Corneal / Q000473:pathology*; D005642:Fuchs' Endothelial Dystrophy / Q000150:complications; D006801:Humans; D019654:Lens Implantation, Intraocular; D008269:Macular Edema / Q000188:drug therapy; D008297:Male; D010648:Phenylacetates / Q000627:therapeutic use; D011183:Postoperative Complications; D019591:Pseudophakia / Q000209:etiology*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology
chemical_list: D044482:Benzeneacetamides; D010648:Phenylacetates; C414203:nepafenac; D000086:Acetazolamide