title: [Status of center point thickness and correlation between anatomic and best corrected visual acuity changes after photocoagulation, in diabetic macular edema].
abstract: BACKGROUND
  Center point thickness in diabetic macular edema varies after photocoagulation according to its baseline status; it is unknown whether this variation reduces the correlation between anatomic and visual acuity changes.
  
  
  OBJECTIVE
  to identify the contribution of baseline center point thickness to the correlation between anatomic and visual acuity after photocoagulation, in eyes with diabetic macular edema.
  
  
  METHODS
  non-experimental, prospective, longitudinal, analytical study in diabetics with macular edema treated with photocoagulation, stratified by groups: visual acuity < 0.5 with (group 1) or without central thickening (group 2), and visual acuity = 0.5 with (group 3) or without central thickening (4). The correlations between changes of center point thickness, macular volume, and visual acuity were identified (Spearman).
  
  
  RESULTS
  79 eyes, 17 in group 1 (21.5%), 21 in group 2 (26.6%), 14 in group 3 (17.7%) and 27 in group 4 (34.2%). Center point thickness increased in groups 2 and 4, visual acuity decreased in group 3 and macular volume in all the groups. The correlations between center point thickness and best corrected visual acuity changes in group 3, and between macular volume and visual acuity in group 1 were negative. The correlations between anatomic variables and visual acuity were low in the sample (r= 0.14).
  
  
  CONCLUSIONS
  the increase of center point thickness in eyes without baseline central thickening produced opposite correlations between groups, which reduced the correlations in the samples. Stratification according to baseline center point thickness would make easier to evaluate other variables that modify the functional outcome after photocoagulation.
authors: Servicio de Oftalmología, Hospital Juárez de México, México DF, Mexico.
authors: Virgilio
authors: V
authors: Lima-Gómez
authors: División de Investigación, Hospital Juárez de México, México DF, Mexico. dulcerazo@yahoo.com.mx.
authors: Dulce Milagros
authors: DM
authors: Razo Blanco-Hernández
mesh_terms: D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications / Q000188:drug therapy; D003930:Diabetic Retinopathy / Q000150:complications*; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D006973:Hypertension / Q000150:complications; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000627:therapeutic use; D008028:Light Coagulation; D008266:Macula Lutea / Q000473:pathology*; D008269:Macular Edema / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin
keywords: diabetic macular edema; diabetic retinopathy; edema macular diabético; grosor retiniano; macular volume; retinal thickness; retinopatía diabética; volumen macular