title: The German Aortic Valve Registry: 1-year results from 13,680 patients with aortic valve disease.
abstract: OBJECTIVE
  The German Aortic Valve Registry (GARY) seeks to provide information on a real-world, all-comers basis for patients undergoing aortic valve interventions. This registry comprises patients undergoing the complete spectrum of transcutaneous and conventional surgical aortic valve interventions. The aim of this study was to use the GARY registry to evaluate conventional and catheter-based aortic valve interventions in several risk groups.
  
  
  METHODS
  A total of 13 860 consecutive patients undergoing intervention for aortic valve disease [conventional aortic valve replacement (AVR) or transvascular/transapical TAVR (TV-/TA-TAVR)] were enrolled in 78 German centres in 2011. Baseline, procedural and outcome data, including quality of life, were acquired up to 1 year post-intervention. Vital status at 1 year was known for 98.1% of patients.
  
  
  RESULTS
  The 1-year mortality rate was 6.7% for conventional AVR patients (n = 6523) and 11.0% for patients who underwent AVR with coronary artery bypass grafting (n = 3464). The 1-year mortality rate was 20.7 and 28.0% in TV- and TA-TAVR patients, respectively (n = 2695 and 1181). However, if patients were stratified into four risk groups by means of the EuroSCORE and the German AV Score, the highest risk cohorts showed the same mortality at 1 year with either therapy. More than 80% of patients in all groups were in the same or better state of health at 1 year post-intervention and were satisfied with the procedural outcome.
  
  
  CONCLUSIONS
  Conventional AVR surgery yields excellent results after 1 year in lower-risk patients. Catheter-based AVR is a good alternative in high-risk and elderly patients.
authors: Heart Center Leipzig, Leipzig, Germany mohrf@medizin.uni-leipzig.de friedrich.mohr@herzzentrum-leipzig.de.
authors: Friedrich W
authors: FW
authors: Mohr
authors: Heart Center Leipzig, Leipzig, Germany.
authors: David
authors: D
authors: Holzhey
authors: Department of Cardiology, Kerckhoff Heart Center, Bad Nauheim, Germany.
authors: Helge
authors: H
authors: Möllmann
authors: Deutsche Gesellschaft für Thorax-, Herz- und Gefäßchirurgie, Langenbeck-Virchow-Haus, Berlin, Germany.
authors: Andreas
authors: A
authors: Beckmann
authors: BQS Institute for Quality and Patient Safety, Düsseldorf, Germany.
authors: Christof
authors: C
authors: Veit
authors: Division of Cardiology, 1st Department of Medicine, University Hospital of Jena, Jena, Germany.
authors: Hans Reiner
authors: HR
authors: Figulla
authors: Department of Cardiovascular Surgery, University of Schleswig-Holstein, Kiel, Germany.
authors: Jochen
authors: J
authors: Cremer
authors: Asklepios Klinik St. Georg, Hamburg, Germany.
authors: Karl-Heinz
authors: KH
authors: Kuck
authors: German Heart Center Munich, Department of Cardiovascular Surgery, Technische Universität München, Munich, Germany.
authors: Rüdiger
authors: R
authors: Lange
authors: Department of Cardiology, Medizinische Klinik B, Herzzentrum am Klinikum Ludwigshafen, Ludwigshafen, Germany.
authors: Ralf
authors: R
authors: Zahn
authors: Klinik für Kardiologie, Pneumologie und Internistische Intensivmedizin, Klinikum Schwabing, Munich, Germany.
authors: Stefan
authors: S
authors: Sack
authors: Heart Center Leipzig, Leipzig, Germany.
authors: Gerhard
authors: G
authors: Schuler
authors: Kerckhoff-Herzzentrum, Abteilung für Herzchirurgie, Bad Nauheim, Germany.
authors: Thomas
authors: T
authors: Walther
authors: Universitätsklinikum Freiburg, Chirurgische Klinik Abteilung Herz- und Gefäßchirurgie, Freiburg, Germany.
authors: Friedhelm
authors: F
authors: Beyersdorf
authors: Medizinische Klinik und Poliklinik, Universitätsklinik des Saarlandes, Innere Medizin III, Homburg/Saar, Germany.
authors: Michael
authors: M
authors: Böhm
authors: Institut für Pathophysiologie, Universitätsklinikum Essen, Essen, Germany.
authors: Gerd
authors: G
authors: Heusch
authors: Heart Center Leipzig, Leipzig, Germany.
authors: Anne-Kathrin
authors: AK
authors: Funkat
authors: Deutsche Herzstiftung, Frankfurt am Main, Germany.
authors: Thomas
authors: T
authors: Meinertz
authors: Department of Cardiology, University of Duisburg-Essen Medical School, Essen, Germany.
authors: Till
authors: T
authors: Neumann
authors: German Cardiac Society, Düsseldorf, Germany.
authors: Konstantinos
authors: K
authors: Papoutsis
authors: Institut für Herzinfarktforschung, Ludwigshafen, Germany.
authors: Steffen
authors: S
authors: Schneider
authors: Department of Cardiac Surgery, University of Bonn, Bonn, Germany.
authors: Armin
authors: A
authors: Welz
authors: Department of Cardiology, Kerckhoff Heart Center, Bad Nauheim, Germany.
authors: Christian W
authors: CW
authors: Hamm
mesh_terms: D001021:Aortic Valve / Q000601:surgery; D000082882:Bicuspid Aortic Valve Disease; D005858:Germany / Q000453:epidemiology; D006330:Heart Defects, Congenital / Q000453:epidemiology / Q000401:mortality / Q000601:surgery*; D006349:Heart Valve Diseases / Q000453:epidemiology / Q000401:mortality / Q000601:surgery*; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000379:methods; D006801:Humans; D011788:Quality of Life; D012042:Registries; D016019:Survival Analysis
keywords: Aortic valve interventions; Aortic valve registry; Catheter-based valve replacement; One-year mortality; Risk groups