title: 3D FIESTA pulse sequence for assessing renal artery stenosis: is it a reliable application in unenhanced magnetic resonance angiography?
abstract: OBJECTIVE
  To assess the capability of the three-dimensional (3D) Fast Imaging Employing Steady-State Acquisition (FIESTA) sequence in evaluating renal artery stenosis (RAS).
  
  
  METHODS
  We retrospectively analysed 79 patients referred for suspected RAS, examined by 3D FIESTA and contrast-enhanced magnetic resonance angiography (CE-MRA), using a 1.5T whole-body scanner. Image quality was assessed as well as the presence and grade of RAS. Patients with RAS ≥ 50% were evaluated for possible digital subtraction angiography (DSA). Sensitivity, specificity, negative predictive value (NPV), positive predictive value (PPV), and accuracy of 3D FIESTA were calculated with ROC analysis using CE-MRA and DSA as the standard of reference.
  
  
  RESULTS
  A total of 186 renal arteries were assessed; 36 had RAS ≥ 50 % demonstrated by CE-MRA. Ten patients underwent DSA, for a total evaluation of 22 arteries. Sensitivity, specificity, NPV, PPV, and accuracy of 3D FIESTA were 91.7%, 100%, 98%, 100%, and 98%, respectively, as compared to CE-MRA, and 88.2%, 100%, 71.4%, 100%, and 91%, respectively, as compared to DSA. The area under the ROC curve (AUC) of 3D FIESTA as compared to CE-MRA and DSA was 0.958 and 0.941, respectively.
  
  
  CONCLUSIONS
  Our study demonstrated the capability of the 3D FIESTA sequence in evaluating RAS, with high-quality images and good diagnostic accuracy.
  
  
  CONCLUSIONS
  The 3D FIESTA sequence provides a robust evaluation of RAS. The 3D FIESTA sequence allows non-invasive evaluation of the renal arteries. The 3D FIESTA sequence could be a useful tool in evaluating RAS.
authors: Radiology Unit, Department of Digestive Diseases and Internal Medicine, University of Bologna, Via Albertoni, 15, 40138, Bologna, Italy, caterina.gaudiano@aosp.bo.it.
authors: Caterina
authors: C
authors: Gaudiano
authors: Fiorenza
authors: F
authors: Busato
authors: Emiliana
authors: E
authors: Ferramosca
authors: Carlo
authors: C
authors: Cecchelli
authors: Beniamino
authors: B
authors: Corcioni
authors: Lucia Barbara
authors: LB
authors: De Sanctis
authors: Antonio
authors: A
authors: Santoro
authors: Rita
authors: R
authors: Golfieri
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015901:Angiography, Digital Subtraction / Q000379:methods; D003287:Contrast Media; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012078:Renal Artery Obstruction / Q000175:diagnosis*; D055815:Young Adult
chemical_list: D003287:Contrast Media