title: Sizing up lung stem cells.
abstract: Mammalian lungs are comprised of conducting airways and alveoli. How the distinct epithelial linings of these two zones are differentially specified and maintained is not fully understood. In this issue of Developmental Cell, two groups find critical roles for the Hippo pathway in regulation of lung progenitor cell differentiation.
authors: Department of Anatomy, University of California, San Francisco, CA 94143, USA. Electronic address: jason.rock@ucsf.edu.
authors: Jason R
authors: JR
authors: Rock
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000378:metabolism*; D053687:Adult Stem Cells / Q000166:cytology*; D000818:Animals; D019521:Body Patterning; D018797:Cell Cycle Proteins; D002454:Cell Differentiation; D049109:Cell Proliferation; D053595:Embryonic Stem Cells / Q000166:cytology*; D004847:Epithelial Cells / Q000166:cytology*; D000090683:Hippo Signaling Pathway; D008168:Lung / Q000166:cytology*; D010750:Phosphoproteins / Q000378:metabolism*; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D014132:Trachea / Q000166:cytology*; D000091102:YAP-Signaling Proteins
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D018797:Cell Cycle Proteins; D010750:Phosphoproteins; D000091102:YAP-Signaling Proteins; C486223:Yap1 protein, mouse; D017346:Protein Serine-Threonine Kinases