title: Is Tumor of Follicular Infundibulum a Reaction to Dermal Scarring?
abstract: Tumor of follicular infundibulum (TFI) is currently believed to be a benign epithelial neoplasm with follicular differentiation. It has been suggested that TFI is associated with dermal scarring, but further investigation is needed to confirm this correlation. To approach this question, a retrospective study was presented, a total of 67 cases (64 lesions) were found in a search covering cases over a 10-year period. Overall, the presence of histological dermal scarring was noted in 34 of 64 (53.13%) cases. Of the cases where TFI was an incidental finding, the presence of dermal scarring was noted in 13 of 18 (72.22%) cases. Meanwhile, of the cases where TFI was the main diagnosis, the presence of dermal scarring was noted in 12 of 34 (35.29%) cases. This suggests that TFI may, in some cases, represent an epidermal reaction pattern to dermal scarring.
authors: *Department of Pathology, Wake Forest School of Medicine, Winston-Salem, NC; †Department of Pathology, King Fahad University Hospital, University of Dammam, Dammam, Saudi Arabia; and ‡Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, NC.
authors: Katherine L
authors: KL
authors: Baquerizo Nole
authors: Dan R
authors: DR
authors: Lopez-Garcia
authors: Daniel J
authors: DJ
authors: Teague
authors: Ahmed
authors: A
authors: Al Sayyah
authors: Parisa
authors: P
authors: Mansoori
authors: Hamza
authors: H
authors: Salim Al Alshehri
authors: Omar P
authors: OP
authors: Sangüeza
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002921:Cicatrix / Q000150:complications / Q000473:pathology*; D005260:Female; D018859:Hair Follicle; D006801:Humans; D033162:Incidental Findings; D008297:Male; D008875:Middle Aged; D018294:Neoplasms, Adnexal and Skin Appendage / Q000150:complications / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology*