title: Cobalt-catalyzed, aminoquinoline-directed C(sp²)-H bond alkenylation by alkynes.
abstract: A method for cobalt-catalyzed, aminoquinoline- and picolinamide-directed C(sp(2))-H bond alkenylation by alkynes was developed. The method shows excellent functional-group tolerance and both internal and terminal alkynes are competent substrates for the coupling. The reaction employs a Co(OAc)2⋅4 H2O catalyst, Mn(OAc)2 co-catalyst, and oxygen (from air) as a terminal oxidant.
authors: Department of Chemistry, University of Houston, Houston, TX 77204-5003 (USA).
authors: Liene
authors: L
authors: Grigorjeva
authors: Olafs
authors: O
authors: Daugulis
mesh_terms: D000478:Alkylation; D000480:Alkynes / Q000737:chemistry*; D000577:Amides / Q000737:chemistry; D000634:Aminoquinolines / Q000737:chemistry*; D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010848:Picolinic Acids / Q000737:chemistry
chemical_list: D000480:Alkynes; D000577:Amides; D000634:Aminoquinolines; D009942:Organometallic Compounds; D010848:Picolinic Acids; D003035:Cobalt; C003142:picolinamide
keywords: CH activation; alkenes; alkynes; cobalt; cyclization