title: [Implantation metastasis of breast cancer in vacuum-assisted breast biopsy needle tract and the impact of neoadjuvant chemotherapy].
abstract: OBJECTIVE
  To study the incidence of implantation metastasis of breast cancer in vacuum-assisted breast biopsy (VABB) needle tract in Chinese patients and evaluate the effect of neoadjuvant chemotherapy on needle tract metastasis following VABB.
  
  
  METHODS
  The breast cancer patients with established diagnosis by VABB were divided into two groups to receive open surgery or neoadjuvant chemotherapy prior to open surgery. The incidence of needle tract metastasis, disease-free survival (DFS) and overall survival (OS) were compared between the two groups.
  
  
  RESULTS
  A total of 214 patients were enrolled, among whom 94 directly underwent surgeries and 120 had neoadjuvant chemotherapy before surgery. The two groups showed no significant differences in the incidence of needle tract metastasis (3.2% vs 0.8%, P=0.206), DFS (P=0.221), or OS (P=0.531).
  
  
  CONCLUSIONS
  The incidence of needle tract metastasis is low after VABB, and neoadjuvant chemotherapy does not increase this risk.
authors: 1Southern Medical University, Guangzhou 510515, China; 2Department of Breast Cancer, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China. E-mail: renjiujiu99@hotmail.com.
authors: Chongyang
authors: C
authors: Ren
authors: Ning
authors: N
authors: Liao
authors: Guochun
authors: G
authors: Zhang
authors: Shengli
authors: S
authors: An
authors: Lingzhu
authors: L
authors: Wen
authors: Xueke
authors: X
authors: Qian
authors: Haitong
authors: H
authors: Lü
mesh_terms: D001707:Biopsy, Needle / Q000379:methods*; D001940:Breast; D001943:Breast Neoplasms / Q000473:pathology*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D015994:Incidence; D009339:Needles; D020360:Neoadjuvant Therapy; D016609:Neoplasms, Second Primary / Q000188:drug therapy*; D014618:Vacuum