title: mTOR: a new therapeutic target for pediatric low-grade glioma?
authors: Division of Neuropathology, Johns Hopkins University, Baltimore, MD, USA.
authors: Fausto J
authors: FJ
authors: Rodriguez
authors: Eric H
authors: EH
authors: Raabe
mesh_terms: D001932:Brain Neoplasms / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D002648:Child; D005910:Glioma / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D060787:Neoplasm Grading; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects; D058570:TOR Serine-Threonine Kinases / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism*
chemical_list: D019869:Phosphatidylinositol 3-Kinases; D058570:TOR Serine-Threonine Kinases; C546842:MTOR protein, human
keywords: mTOR; neurofibromatosis; optic nerve; pediatric glioma; pilocytic astrocytoma