title: Glucocerebrosidase inhibitors: future drugs for the treatment of Gaucher disease?
authors: Laboratory of Medicinal Chemistry, Department of Biomedicinal Chemistry, Institut de Química Avançada de Catalunya (IQAC-CSIC), Jordi Girona 18-26, 08034 Barcelona, Spain.
authors: Ana
authors: A
authors: Trapero
authors: Amadeu
authors: A
authors: Llebaria
mesh_terms: D015195:Drug Design; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use*; D005776:Gaucher Disease / Q000188:drug therapy* / Q000201:enzymology / Q000378:metabolism; D005962:Glucosylceramidase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006801:Humans; D013329:Structure-Activity Relationship
chemical_list: D004791:Enzyme Inhibitors; D005962:Glucosylceramidase
keywords: Gaucher disease; glucocerebrosidase; inhibitors; lysosomal storage disorders; pharmacological chaperone; rare disease