title: Presentation and initial assessment of ENT problems in patients with granulomatosis with polyangiitis (Wegener's).
abstract: BACKGROUND
  Granulomatosis with polyangiitis (formerly known as Wegener's granulomatosis) is a primary systemic vasculitis that affects medium to small sized vessels throughout the body. It often presents with symptoms and signs involving the ear, nose, and head and neck area.
  
  
  OBJECTIVE
  To highlight salient features of ENT-related issues in granulomatosis with polyangiitis, and raise awareness of the condition.
  
  
  METHODS
  A case report of a patient with limited disease and an insidious onset is presented, along with a review of the current literature. In addition, basic initial management is described.
  
  
  RESULTS
  Eighty-six publications were used to describe salient features of ENT-related issues in granulomatosis with polyangiitis.
  
  
  CONCLUSIONS
  The time to diagnosis has not reduced significantly in the last 10 years in the UK. A high index of suspicion is required for an earlier diagnosis of granulomatosis with polyangiitis.
authors: Department of Otolaryngology,Addenbrooke's Hospital,Cambridge University Hospitals NHS Foundation Trust,UK.
authors: M
authors: M
authors: Martinez Del Pero
authors: Department of Otolaryngology,Addenbrooke's Hospital,Cambridge University Hospitals NHS Foundation Trust,UK.
authors: D
authors: D
authors: McKiernan
authors: Department of Otolaryngology,Addenbrooke's Hospital,Cambridge University Hospitals NHS Foundation Trust,UK.
authors: P
authors: P
authors: Jani
mesh_terms: D000328:Adult; D004427:Ear Diseases / Q000175:diagnosis; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D009668:Nose Diseases / Q000175:diagnosis; D010608:Pharyngeal Diseases / Q000175:diagnosis