title: Application of platelet-rich plasma in the treatment of chronic skin ulcer - case report.
abstract: The platelet-rich plasma (PRP) has proved promising regarding its applicability in dermatology, especially in the healing of chronic ulcers. The autologous platelet-rich plasma is obtained by centrifuging the blood, so that the components are separated by density gradient. The final product is a gel rich in growth factors that act in tissue repair by activating fibroblasts and inducing extracellular matrix remodeling.
authors: Universidade Federal Fluminense, Niterói, RJ, Brazil.
authors: Jane Marcy Neffá
authors: JM
authors: Pinto
authors: Universidade Federal Fluminense, Niterói, RJ, Brazil.
authors: Natássia Soares
authors: NS
authors: Pizani
authors: Universidade Federal Fluminense, Niterói, RJ, Brazil.
authors: Hye Chung
authors: HC
authors: Kang
authors: Universidade Federal Fluminense, Niterói, RJ, Brazil.
authors: Luis Augusto Knecht
authors: LA
authors: Silva
mesh_terms: D000368:Aged; D001804:Blood Transfusion, Autologous / Q000379:methods; D002908:Chronic Disease; D005260:Female; D005782:Gels / Q000627:therapeutic use; D006801:Humans; D017713:Platelet Transfusion / Q000379:methods; D053657:Platelet-Rich Plasma; D012883:Skin Ulcer / Q000473:pathology / Q000628:therapy*; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D005782:Gels