title: Esophageal dilations in eosinophilic esophagitis: a single center experience.
abstract: OBJECTIVE
  To diagnose the clinical and histologic features that may be associated with or predictive of the need for dilation and dilation related complications; examine the safety of dilation in patients with eosinophilic esophagitis (EoE).
  
  
  METHODS
  The medical records of all patients diagnosed with EoE between January 2002 and July 2010 were retrospectively reviewed. Esophageal biopsies were reexamined by an experienced pathologist to confirm the diagnosis (≥ 15 eos/hpf per current guidelines). Patients were divided into 2 groups: patients who did not receive dilation therapy and those who did. Demographics, clinical history, the use of pharmacologic therapy, endoscopic and pathology findings, and the number of biopsies and dilations carried out, if any, and their locations were recorded for each patient. The dilation group was further examined based on the interval between diagnosis and dilation, and whether or not a complication occurred.
  
  
  RESULTS
  Sixty-one patients were identified with EoE and 22 (36%) of them underwent esophageal dilations for stricture/narrowing. The peak eos/hpf was significantly higher in patients who received a dilation (P = 0.04). Four (18% of pts.) minor complications occurred: deep mucosal tear 1, and small mucosal tears 3. There were no cases of esophageal perforations. Higher peak eos/hpf counts were not associated with increased risk of complications.
  
  
  CONCLUSIONS
  Esophageal dilation appears to be a safe procedure in EoE patients, carrying a low complication rate. No correlation was found between the peak of eosinophil count and complication rate. Complications can occur independently of the histologic features. The long-term outcome of EoE treatment, with or without dilation, needs to be determined.
authors: Andrew Ukleja, Jennifer Shiroky, Department of Gastroenterology, Cleveland Clinic Florida, Weston, FL 33331, United States.
authors: Andrew
authors: A
authors: Ukleja
authors: Andrew Ukleja, Jennifer Shiroky, Department of Gastroenterology, Cleveland Clinic Florida, Weston, FL 33331, United States.
authors: Jennifer
authors: J
authors: Shiroky
authors: Andrew Ukleja, Jennifer Shiroky, Department of Gastroenterology, Cleveland Clinic Florida, Weston, FL 33331, United States.
authors: Amitesh
authors: A
authors: Agarwal
authors: Andrew Ukleja, Jennifer Shiroky, Department of Gastroenterology, Cleveland Clinic Florida, Weston, FL 33331, United States.
authors: Daniela
authors: D
authors: Allende
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy; D004106:Dilatation / Q000009:adverse effects / Q000379:methods*; D057765:Eosinophilic Esophagitis / Q000175:diagnosis / Q000628:therapy*; D004940:Esophageal Stenosis / Q000175:diagnosis / Q000628:therapy*; D004945:Esophagoscopy; D005260:Female; D005431:Florida; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
keywords: Balloon dilation; Dysphagia; Esophageal stricture; Esophagus disorder; Esosinophilic esophagitis