title: Prioritized current unmet needs for antibacterial therapies.
abstract: As a result of declining new antibacterial approvals and rising antibiotic resistance, society clearly needs new treatments for bacterial infections. Specific areas of unmet need evolve over time owing to changes in resistance patterns and treatment strategies. Our goal here is to describe and prioritize the current areas of greatest unmet need for new antibacterial development based on an understanding of the most serious treatment challenges facing patients and their providers today.
authors: Division of Infectious Diseases, Keck School of Medicine at the University of Southern California and LAC+USC Medical Center, Los Angeles, California, USA.
authors: B
authors: B
authors: Spellberg
authors: Stonington, Connecticut, USA.
authors: D
authors: D
authors: Shlaes
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology; D015195:Drug Design; D024901:Drug Resistance, Multiple, Bacterial / Q000187:drug effects* / Q000502:physiology; D006292:Health Priorities / Q000639:trends*; D006301:Health Services Needs and Demand / Q000639:trends*; D006801:Humans
chemical_list: D000900:Anti-Bacterial Agents