title: First finding of Southeast Asia topotype of foot-and-mouth disease virus in Kinmen, Taiwan, in the 2012 outbreak.
abstract: Foot-and-mouth disease virus, a member of genus Aphthovirus within the family Picornaviridae, affects cloven-hoofed animals, causing foot-and-mouth disease characterized by vesicle development. The Southeast Asia topotype, one of the topotypes within serotype O of the virus, is prevalent in some Asian countries, but had not previously been found in Taiwan. The topotype was first found in pigs in Kinmen Island, Taiwan, in 2012 and identified by nucleotide sequence comparison and phylogenetic analysis. Outbreaks were reported at 4 farms, resulting in the culling of 628 pigs and 1 cattle. Pigs were the only species infected during the outbreak. The incursion of Southeast Asia topotype into Taiwan implies the expansion of the topotype in East Asia.
authors: Animal Health Research Institute, 376 Chung Cheng Road, Tamsui District, New Taipei City 25158, Taiwan.
authors: Yeou-Liang
authors: YL
authors: Lin
authors: Chia-Yi
authors: CY
authors: Chang
authors: Chu-Hsiang
authors: CH
authors: Pan
authors: Ming-Chung
authors: MC
authors: Deng
authors: Hsiang-Jung
authors: HJ
authors: Tsai
authors: Fan
authors: F
authors: Lee
mesh_terms: D000818:Animals; D001483:Base Sequence; D016000:Cluster Analysis; D017931:DNA Primers / Q000235:genetics; D004196:Disease Outbreaks / Q000266:history / Q000662:veterinary*; D004797:Enzyme-Linked Immunosorbent Assay; D005536:Foot-and-Mouth Disease / Q000453:epidemiology* / Q000821:virology; D029544:Foot-and-Mouth Disease Virus / Q000145:classification / Q000235:genetics*; D005843:Geography; D049674:History, 21st Century; D008969:Molecular Sequence Data; D010802:Phylogeny; D020133:Reverse Transcriptase Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D013552:Swine; D013624:Taiwan / Q000453:epidemiology
chemical_list: D017931:DNA Primers