title: Mechanochemical C-H bond activation: rapid and regioselective double cyclopalladation monitored by in situ Raman spectroscopy.
abstract: The first direct mechanochemical transition-metal-mediated activation of strong phenyl C-H bonds is reported. The mechanochemical procedure, resulting in cyclopalladated complexes, is quantitative and significantly faster than solution synthesis and allows highly regioselective activation of two C-H bonds by palladium(II) acetate in asymmetrically substituted azobenzene. Milling is monitored by in situ solid-state Raman spectroscopy which in combination with quantum-chemical calculations enabled characterization of involved reaction species, direct insight into the dynamics and reaction pathways, as well as the optimization of a milling process.
authors: Ruđer Bošković Institute, Bijenička 54, HR-10000 Zagreb, Croatia. curic@irb.hr.
authors: Marina
authors: M
authors: Juribašić
authors: Krunoslav
authors: K
authors: Užarević
authors: Davor
authors: D
authors: Gracin
authors: Manda
authors: M
authors: Ćurić