title: Rhodium-catalyzed transannulation of 1,2,3-triazoles to polysubstituted pyrroles.
abstract: Rhodium-catalyzed transannulation of N-sulfonyl-1,2,3-triazoles with vinyl ether has been accomplished for the synthesis of various polysubstituted pyrroles. The present method allows the synthesis of mono-, di-, and trisubstituted pyrroles with appropriate substitutions. Furthermore, the developed methodology was applied in the formal synthesis of neolamellarin A, an antitumor agent.
authors: Department of Chemistry, Indian Institute of Technology Madras , Chennai - 600036, India.
authors: Shanmugam
authors: S
authors: Rajasekar
authors: Pazhamalai
authors: P
authors: Anbarasan
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D002384:Catalysis; D015394:Molecular Structure; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D012238:Rhodium / Q000737:chemistry*; D014230:Triazoles / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D000970:Antineoplastic Agents; D011758:Pyrroles; D014230:Triazoles; C543768:neolamellarin A; D012238:Rhodium