title: Thyroid storm complicated by bicytopenia and disseminated intravascular coagulation.
abstract: METHODS
  Male, 23.
  
  
  METHODS
  Thyroid storm.
  
  
  METHODS
  Delirium • diarrhea • fever • hypertension • hyperventilation • tachycardia • weight loss.
  
  
  METHODS
  -.
  
  
  METHODS
  -.
  
  
  METHODS
  Endocrinology and Metabolic.
  
  
  OBJECTIVE
  Unusual clinical course.
  
  
  BACKGROUND
  The clinical presentation of thyroid storm includes fever, tachycardia, hypertension, and neurological abnormalities. It is a serious condition with a high mortality rate. Furthermore, some other complications affect the clinical course of thyroid storm. Although it is reported that prognosis is poor when thyroid storm is complicated by disseminated intravascular coagulation syndrome (DIC) and leukopenia, reports of such cases are rare.
  
  
  METHODS
  A 23-year-old man presented with delirium, high pyrexia, diarrhea, and weight loss of 18 kg over 2 months. According to the criteria of Burch and Wartofsky, he was diagnosed with thyroid storm on the basis of his symptom-complex and laboratory data that confirmed the presence of hyperthyroidism. Investigations also found leukopenia, thrombocytopenia, and disseminated intravascular coagulation, all of which are very rare complications of thyroid storm. We successfully treated him with combined therapy including anti-thyroid medication, despite leukopenia.
  
  
  CONCLUSIONS
  Early diagnosis and treatment are essential in ensuring a good outcome for patients with this rare combination of medical problems.
authors: Department of General Medicine, Saga University Hospital, Saga city, Japan.
authors: Yoshinori
authors: Y
authors: Tokushima
authors: Community Medical Support Institute, Faculty of Medicine, Saga University Hospital, Saga city, Japan.
authors: Yuta
authors: Y
authors: Sakanishi
authors: Department of General Medicine, Saga University Hospital, Saga city, Japan.
authors: Kou
authors: K
authors: Nagae
authors: Department of General Medicine, Saga University Hospital, Saga city, Japan.
authors: Midori
authors: M
authors: Tokushima
authors: Department of General Medicine, Saga University Hospital, Saga city, Japan.
authors: Masaki
authors: M
authors: Tago
authors: Department of General Medicine, Saga University Hospital, Saga city, Japan.
authors: Motosuke
authors: M
authors: Tomonaga
authors: Department of General Medicine, Saga University Hospital,, Saga city, Japan.
authors: Tsuneaki
authors: T
authors: Yoshioka
authors: Department of General Medicine, Saga University Hospital, Saga city, Japan.
authors: Masaki
authors: M
authors: Hyakutake
authors: Community Medical Support Institute, Faculty of Medicine, Saga University Hospital, Saga city, Japan.
authors: Takashi
authors: T
authors: Sugioka
authors: Department of General Medicine, Saga University Hospital, Saga city, Japan.
authors: Shu-ichi
authors: S
authors: Yamashita
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D013956:Antithyroid Agents / Q000627:therapeutic use; D004211:Disseminated Intravascular Coagulation / Q000188:drug therapy / Q000209:etiology*; D004359:Drug Therapy, Combination; D006801:Humans; D007452:Iodates / Q000627:therapeutic use; D007958:Leukocyte Count; D007970:Leukopenia / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008713:Methimazole / Q000627:therapeutic use; D017680:Potassium Compounds / Q000627:therapeutic use; D011433:Propranolol / Q000627:therapeutic use; D013958:Thyroid Crisis / Q000150:complications* / Q000188:drug therapy; D055815:Young Adult
chemical_list: D000319:Adrenergic beta-Antagonists; D013956:Antithyroid Agents; D007452:Iodates; D017680:Potassium Compounds; D008713:Methimazole; D011433:Propranolol; C039693:potassium iodate