title: Biomarkers as predictors of recurrence following curative resection for pancreatic ductal adenocarcinoma: a review.
abstract: Pancreatic ductal adenocarcinoma (PDA) is the fourth most common cancer causing death in the United States. Early tumor recurrence is an important contributor to the dismal prognosis. The availability of an accurate prognostic biomarker for predicting disease recurrence following curative resection will be beneficial for patient care. Most of the currently studied biomarkers remain in the investigational phase, with CA 19-9 being the only biomarker currently approved by the FDA. Herein, we review the utility of CA 19-9 and other investigational cellular, gene, and molecular tumor markers for predicting PDA recurrence following curative surgical resection.
authors: Department of Surgery and Center for Minimally Invasive Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
authors: Sylvester N
authors: SN
authors: Osayi
authors: Department of Surgery and Center for Minimally Invasive Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
authors: Mark
authors: M
authors: Bloomston
authors: Department of Surgery and Center for Minimally Invasive Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
authors: Carl M
authors: CM
authors: Schmidt
authors: Department of Surgery and Center for Minimally Invasive Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
authors: E Christopher
authors: EC
authors: Ellison
authors: Department of Surgery and Center for Minimally Invasive Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
authors: Peter
authors: P
authors: Muscarella
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery*; D014408:Biomarkers, Tumor / Q000378:metabolism*; D021441:Carcinoma, Pancreatic Ductal / Q000601:surgery*; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000601:surgery*; D010190:Pancreatic Neoplasms / Q000601:surgery*
chemical_list: D014408:Biomarkers, Tumor