title: Amoebic anal fistula: new insight into an old disease.
abstract: A 67-year-old gentleman underwent fistulectomy for low trans-sphincteric anal fistula along with curettage for an associated abscess extending proximally for half a centimeter into the intersphincteric plane. The roof of the cavity became clearly visible after satisfactory culmination of the surgical procedure. Histopathological examination of the fistulous tract and the curetted granulation tissue revealed presence of multiple trophozoites of Entamoeba histolytica exhibiting erythrophagocytosis in the background of mixed inflammatory infiltrate. This case report provides the outlook that yields the novel insight into the possible role of Entamoeba histolytica in the pathogenesis and persistence of the fistulous tract.
authors: Department of Surgery, University College of Medical Sciences and Guru Teg Bahadur Hospital, University of Delhi, New Delhi, India.
authors: Vivek
authors: V
authors: Agrawal
authors: Pankaj Kumar
authors: PK
authors: Garg
authors: Bhupendra Kumar
authors: BK
authors: Jain
authors: Kiran
authors: K
authors: Mishra
authors: Debajyoti
authors: D
authors: Mohanty
mesh_terms: D000038:Abscess / Q000469:parasitology* / Q000473:pathology / Q000628:therapy; D000368:Aged; D004748:Entamoeba histolytica; D004749:Entamoebiasis / Q000150:complications*; D006801:Humans; D008297:Male; D012003:Rectal Fistula / Q000469:parasitology* / Q000473:pathology / Q000628:therapy