title: Old medications and new targeted therapies in systemic sclerosis.
abstract: SSc is a multiorgan disease with significant morbidity that is associated with poor health-related quality of life. Treatment of this condition is often organ based and non-curative. However, there are newer, potentially disease-modifying therapies available to treat certain aspects of the disease. This review focuses on old and new therapies in the management of SSc in clinical practice.
authors: Division of Rheumatology, University of Michigan, Ann Arbor, MI, USA and.
authors: Vivek
authors: V
authors: Nagaraja
authors: Division of Medicine, University College London, London, UK.
authors: Christopher P
authors: CP
authors: Denton
authors: Division of Rheumatology, University of Michigan, Ann Arbor, MI, USA and khannad@med.umich.edu.
authors: Dinesh
authors: D
authors: Khanna
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use*; D004358:Drug Therapy / Q000639:trends*; D005355:Fibrosis / Q000209:etiology; D006801:Humans; D012595:Scleroderma, Systemic / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D012867:Skin / Q000473:pathology; D014652:Vascular Diseases / Q000209:etiology
chemical_list: D018501:Antirheumatic Agents
keywords: Raynaud’s phenomenon; digital ulcers; immunosuppressive therapy; interstitial lung disease; pulmonary arterial hypertension; renal crisis; skin fibrosis; systemic sclerosis; treatment