title: Surgery. NSAIDs and risk of anastomotic leaks after colorectal surgery.
abstract: NSAIDs provide improved pain control and reduce the use of opioids--both important components of enhanced recovery programs after colorectal surgery. However, the possible association between NSAID use and anastomotic leaks is greatly debated. Anastomotic leak remains an important concern due to the substantial associated morbidity.
authors: Division of General Surgery, Department of Surgery, University Hospital, Western University, 339 Windermere Road, Room C8-128, London, Ontario N6A 5A5, Canada.
authors: Julie Ann M
authors: JA
authors: Van Koughnett
authors: Department of Colorectal Surgery, Digestive Disease Institute, Cleveland Clinic Florida, 2950 Cleveland Clinic Boulevard, Weston, FL 33331, USA.
authors: Steven D
authors: SD
authors: Wexner
mesh_terms: D057868:Anastomotic Leak / Q000139:chemically induced*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D003106:Colon / Q000601:surgery*; D017558:Elective Surgical Procedures; D005260:Female; D006801:Humans; D007082:Ileum / Q000601:surgery*; D020910:Ketorolac / Q000009:adverse effects*; D008297:Male; D019990:Perioperative Care / Q000009:adverse effects*; D012007:Rectum / Q000601:surgery*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D020910:Ketorolac