title: High-Sensitivity C-Reactive Protein and Statin Initiation.
abstract: The assessment of cardiovascular risk and treatment of cardiovascular diseases are major public health issues worldwide. Inflammation is now recognized as a key regulatory process that links multiple risk factors for atherosclerosis. The substantial number of patients having cardiovascular events lack commonly established risk factors. The utility of high-sensitivity C-reactive protein (hsCRP), a circulating biomarker related to inflammation, may provide additional information in risk prediction. This review will consider the impact of hsCRP level on initiation of statin therapy.
authors: Laboratory of Radiobiology and Molecular Genetics and Laboratory for Molecular Biology and Endocrinology, Vinca Institute of Nuclear Sciences, University of Belgrade, Belgrade, Serbia.
authors: Andreja
authors: A
authors: Trpkovic
authors: Laboratory of Radiobiology and Molecular Genetics and Laboratory for Molecular Biology and Endocrinology, Vinca Institute of Nuclear Sciences, University of Belgrade, Belgrade, Serbia.
authors: Julijana
authors: J
authors: Stanimirovic
authors: Department of Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy.
authors: Manfredi
authors: M
authors: Rizzo
authors: Laboratory of Radiobiology and Molecular Genetics and Laboratory for Molecular Biology and Endocrinology, Vinca Institute of Nuclear Sciences, University of Belgrade, Belgrade, Serbia.
authors: Ivana
authors: I
authors: Resanovic
authors: Laboratory of Radiobiology and Molecular Genetics and Laboratory for Molecular Biology and Endocrinology, Vinca Institute of Nuclear Sciences, University of Belgrade, Belgrade, Serbia.
authors: Sanja
authors: S
authors: Soskic
authors: Faculty of Stomatology in Pancevo, University Business Academy in Novi Sad, Pancevo, Serbia.
authors: Danimir
authors: D
authors: Jevremovic
authors: Laboratory of Radiobiology and Molecular Genetics and Laboratory for Molecular Biology and Endocrinology, Vinca Institute of Nuclear Sciences, University of Belgrade, Belgrade, Serbia isenovic@yahoo.com.
authors: Esma R
authors: ER
authors: Isenovic
mesh_terms: D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis*; D002318:Cardiovascular Diseases / Q000097:blood / Q000209:etiology / Q000517:prevention & control*; D050171:Dyslipidemias / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D007249:Inflammation / Q000097:blood* / Q000150:complications; D018836:Inflammation Mediators / Q000097:blood*; D017410:Practice Guidelines as Topic; D011237:Predictive Value of Tests; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D018836:Inflammation Mediators; D002097:C-Reactive Protein
keywords: C-reactive protein; biomarker; cardiovascular disease; high-sensitivity C-reactive protein; inflammation; statins