title: Mitochondrial plasticity with exercise training and extreme environments.
abstract: Mitochondria form a reticulum in skeletal muscle. Exercise training stimulates mitochondrial biogenesis, yet an emerging hypothesis is that training also induces qualitative regulatory changes. Substrate oxidation, oxygen affinity, and biochemical coupling efficiency may be regulated differentially with training and exposure to extreme environments. Threshold training doses inducing mitochondrial upregulation remain to be elucidated considering fitness level.
authors: 1Åstrand Laboratory, The Swedish School of Sport and Health Sciences, Stockholm, Sweden; 2Center for Integrative Human Physiology, Institute of Physiology, University of Zurich, Zurich, Switzerland; and 3Department of Biomedical Sciences, Core Facility for Integrated Microscopy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
authors: Robert
authors: R
authors: Boushel
authors: Carsten
authors: C
authors: Lundby
authors: Klaus
authors: K
authors: Qvortrup
authors: Kent
authors: K
authors: Sahlin
mesh_terms: D004734:Energy Metabolism; D004777:Environment; D006801:Humans; D008931:Mitochondria, Muscle / Q000378:metabolism* / Q000648:ultrastructure; D063269:Mitochondrial Turnover; D018482:Muscle, Skeletal / Q000378:metabolism*; D010085:Oxidative Phosphorylation; D010101:Oxygen Consumption; D010806:Physical Education and Training / Q000379:methods*; D010807:Physical Endurance / Q000502:physiology*