title: Vitamin D status in non-supplemented postmenopausal Taiwanese women with osteoporosis and fragility fracture.
abstract: BACKGROUND
  Vitamin D is essential for calcium metabolism, Vitamin D deficiency can precipitate osteoporosis, cause muscle weakness and increase the risk of fracture. The aim of this study was to assess the prevalence of vitamin D inadequacy among non-supplemented postmenopausal women with osteoporosis and fragility fractures of the hip or vertebrae in Taiwan.
  
  
  METHODS
  This multi-center, cross-sectional, observational study analyzed the vitamin D inadequacy [defined as 25(OH) D level less than 30 ng/mL] in Taiwanese postmenopausal osteoporotic patients who suffered from a low trauma, non-pathological fragility hip or vertebral fracture that received post-fracture medical care when admitted to hospital or at an outpatient clinic.
  
  
  RESULTS
  A total of 199 patients were enrolled at 8 medical centers in Taiwan; 194 patients met the study criteria with 113 (58.2%) and 81 (41.8%) patients diagnosed with hip and vertebral fracture, respectively. The mean serum 25(OH) D level was 21.1 ± 9.3 ng/mL, resulting in a prevalence of vitamin D inadequacy of 86.6% of the patients.
  
  
  CONCLUSIONS
  High prevalence of vitamin D inadequacy across all age groups was found among non-supplemented women with osteoporosis and fragility hip or vertebral fracture in Taiwan.
authors: Jawl-Shan
authors: JS
authors: Hwang
authors: Keh-Sung
authors: KS
authors: Tsai
authors: Yuh-Min
authors: YM
authors: Cheng
authors: Wen-Jer
authors: WJ
authors: Chen
authors: Shih-Te
authors: ST
authors: Tu
authors: Ko-Hsiu
authors: KH
authors: Lu
authors: Sheng-Mou
authors: SM
authors: Hou
authors: Shu-Hua
authors: SH
authors: Yang
authors: Henrich
authors: H
authors: Cheng
authors: Hung Jen
authors: HJ
authors: Lai
authors: Sharon
authors: S
authors: Lei
authors: Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, 123, Ta-Pei Road, Niao-Sung Hsiang, Kaohsiung, Taiwan. chenjf56090@gmail.com.
authors: Jung-Fu
authors: JF
authors: Chen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D003430:Cross-Sectional Studies; D005260:Female; D006620:Hip Fractures / Q000175:diagnosis / Q000453:epidemiology*; D006801:Humans; D008875:Middle Aged; D010024:Osteoporosis / Q000175:diagnosis / Q000453:epidemiology*; D058866:Osteoporotic Fractures / Q000175:diagnosis / Q000453:epidemiology*; D015995:Prevalence; D016103:Spinal Fractures / Q000175:diagnosis / Q000453:epidemiology*; D013624:Taiwan / Q000453:epidemiology; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*
chemical_list: D015415:Biomarkers; D014807:Vitamin D; C104450:25-hydroxyvitamin D