title: A one-pot synthetic strategy for construction of the dibenzodiazepine skeleton via a transition metal-free process.
abstract: A one-pot transition metal-free methodology for constructing pharmacologically active dibenzodiazepine derivatives was developed. Fluoro-, bromo- and nitro-substituted aryl aldehydes were applied to this reaction efficiently.
authors: Key Laboratory of Special Functional Aggregated Materials, Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan, 250100, P. R. China.
authors: Shuai
authors: S
authors: Fang
authors: Xiaoyi
authors: X
authors: Niu
authors: Zeyuan
authors: Z
authors: Zhang
authors: Yan
authors: Y
authors: Sun
authors: Xiaomeng
authors: X
authors: Si
authors: Cuicui
authors: C
authors: Shan
authors: Lei
authors: L
authors: Wei
authors: Aiqing
authors: A
authors: Xu
authors: Lei
authors: L
authors: Feng
authors: Chen
authors: C
authors: Ma
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D001569:Benzodiazepines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D015195:Drug Design; D008670:Metals / Q000737:chemistry; D015394:Molecular Structure; D004364:Pharmaceutical Preparations / Q000737:chemistry; D013696:Temperature; D028561:Transition Elements
chemical_list: D000447:Aldehydes; D008670:Metals; D004364:Pharmaceutical Preparations; D028561:Transition Elements; D001569:Benzodiazepines