title: Transfer, transformation, and impacts of ceria nanomaterials in aquatic mesocosms simulating a pond ecosystem.
abstract: Mesocosms are an invaluable tool for addressing the complex issue of exposure during nanoecotoxicological testing. This experimental strategy was used to take into account parameters as the interactions between the NPs and naturally occurring (in)organic colloids (heteroaggregation), or the flux between compartments of the ecosystems (aqueous phase, sediments, biota) when assessing the impacts of CeO2 NPs in aquatic ecosystems. In this study, we determine the transfer, redox transformation, and impacts of 1 mg L(-1) of bare and citrate coated CeO2-NPs toward an ecologically relevant organism (snail, Planorbarius corneus) exposed 4 weeks in a complex experimental system mimicking a pond ecosystem. Over time, CeO2-NPs tend to homo- and heteroaggregate and to accumulate on the surficial sediment. The kinetic of settling down was coating-dependent and related to the coating degradation. After 4 weeks, Ce was observed in the digestive gland of benthic organisms and associated with 65-80% of Ce(IV) reduction into Ce(III) for both bare and coated CeO2 NPs. A transitory oxidative stress was observed for bare CeO2-NPs. Coated-NPs exposed snails did not undergo any lipid peroxidation nor change in the antioxidant contents, while Ce content and reduction in the digestive gland were identical to bare CeO2-NPs. We hypothesized that the presence of citrate coating enhanced the defense capacity of the cells toward the oxidative stress induced by the CeO2 core.
authors: CNRS, Aix-Marseille Université, CEREGE UM34, UMR 7330, 13545 Aix en Provence, France.
authors: Tella
authors: T
authors: Marie
authors: Auffan
authors: A
authors: Mélanie
authors: Brousset
authors: B
authors: Lenka
authors: Issartel
authors: I
authors: Julien
authors: Kieffer
authors: K
authors: Isabelle
authors: Pailles
authors: P
authors: Christine
authors: Morel
authors: M
authors: Elise
authors: Santaella
authors: S
authors: Catherine
authors: Angeletti
authors: A
authors: Bernard
authors: Artells
authors: A
authors: Ester
authors: Rose
authors: R
authors: Jérôme
authors: Thiéry
authors: T
authors: Alain
authors: Bottero
authors: B
authors: Jean-Yves
mesh_terms: D000818:Animals; D059001:Aquatic Organisms / Q000737:chemistry; D002563:Cerium / Q000032:analysis* / Q000378:metabolism; D002951:Citrates / Q000737:chemistry; D003102:Colloids; D017753:Ecosystem; D019015:Geologic Sediments / Q000737:chemistry*; D007700:Kinetics; D053768:Metal Nanoparticles / Q000032:analysis*; D008962:Models, Theoretical; D061005:Ponds / Q000737:chemistry*; D012908:Snails / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000378:metabolism
chemical_list: D002951:Citrates; D003102:Colloids; D014874:Water Pollutants, Chemical; D002563:Cerium