title: [Rat tissues antioxidant status correction by peptide delta sleep during physiological aging of the organism].
abstract: It is shown that exogenous delta-sleep inducing peptide increases glutathione antioxidant system level in rat tissues at different stages of ontogenesis, by subcutaneous injection to rats 2-24 months postnatal development in a dose of 100 mg/kg animal body weight by courses of 5 consecutive days per month, and this effect is especially marked in non-renewable postmitotic tissues.
authors: T I
authors: TI
authors: Bondarenko
authors: D S
authors: DS
authors: Kutilin
authors: I I
authors: II
authors: Mikhaleva
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology; D000367:Age Factors; D000375:Aging / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D000818:Animals; D000975:Antioxidants / Q000502:physiology*; D016922:Cellular Senescence / Q000187:drug effects / Q000502:physiology; D003701:Delta Sleep-Inducing Peptide / Q000008:administration & dosage / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism*; D005979:Glutathione Peroxidase / Q000378:metabolism; D005980:Glutathione Reductase; D005982:Glutathione Transferase / Q000378:metabolism*; D051381:Rats
chemical_list: D000975:Antioxidants; D003701:Delta Sleep-Inducing Peptide; D005979:Glutathione Peroxidase; D005980:Glutathione Reductase; D005982:Glutathione Transferase; D005978:Glutathione