title: Fecal volatile organic compounds: a novel, cheaper method of diagnosing inflammatory bowel disease?
abstract: The investigation of a novel, cheaper method of diagnosing inflammatory bowel disease (IBD) is an area of active research. Recently, investigations into the metabolomic profile of IBD patients and animal models of colitis compared to healthy controls has begun to receive considerable attention and correlations between the fecal volatile organic compound (VOC) metabolome and IBD is merging. Patients and clinicians have often reported a change in odor of feces during relapse of IBD. Therefore, this article will focus specifically on the fecal VOC metabolome and its potential role in identifying a novel diagnostic method for IBD.
authors: Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, Liverpool, L69 3BX, UK.
authors: Chris S J
authors: CS
authors: Probert
authors: Sophie
authors: S
authors: Reade
authors: Iftikhar
authors: I
authors: Ahmed
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D005243:Feces / Q000737:chemistry* / Q000382:microbiology; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology; D007413:Intestinal Mucosa / Q000378:metabolism*; D007422:Intestines / Q000276:immunology / Q000382:microbiology; D055442:Metabolome / Q000276:immunology; D064307:Microbiota; D009812:Odorants / Q000032:analysis; D055549:Volatile Organic Compounds / Q000032:analysis* / Q000276:immunology
chemical_list: D055549:Volatile Organic Compounds
keywords: diagnostic; feces; inflammatory bowel disease; novel; volatile organic compound