title: The relationship between bone mineral density and blood pressure in the Korean elderly population: the Korea National Health and Nutrition Examination Survey, 2008-2011.
abstract: It is not clear whether the inverse relationship between bone mineral density (BMD) and blood pressure (BP) could be generalizable to the general elderly population. We used data from the fourth and fifth Korea National Health and Nutrition Examination Survey. The study sample consisted of 8439 men and postmenopausal women aged 50 years and older. We evaluated the relationship between BMD and BP. When adjusted for covariates, femur neck T-score [coefficient = -0.391, 95% confidence interval (CI) -0.766 to -0.016, p = 0.041] had an inverse relationship with diastolic BP (DBP), whereas lumbar spine BMD (coefficient = 0.395, 95% CI 0.058-7.752, p = 0.047) and T-score (coefficient = 0.458, 95% CI 0.005-0.911, p = 0.047) had a positive relationship with systolic BP (SBP). When adjusted for confounding factors, SBP (128.67 ± 0.979 mmHg versus 126.36 ± 0.545 mmHg, p = 0.026) and DBP (78.8 ± 0.622 mmHg versus 77.27 ± 0.283 mmHg, p = 0.016) were significantly higher in femur neck osteoporosis subjects than non-osteoporosis subjects. However, there were no differences in BP in relation to lumbar spine osteoporosis. Femur neck osteoporosis (odds ratio = 1.422, 95% CI 1.107-1.827, p = 0.006) had a significant and positive relationship with hypertension, whereas the other parameters of BMD were not significantly related to hypertension. In conclusion, higher BP and hypertension were significantly and positively correlated with femur neck osteoporosis in men and postmenopausal women aged 50 years and older.
authors: Division of Cardiology, Department of Internal Medicine, Hanyang University Medical Center , Seoul , Korea and.
authors: Hyung Tak
authors: HT
authors: Lee
authors: Jinho
authors: J
authors: Shin
authors: Seung Yeon
authors: SY
authors: Min
authors: Young-Hyo
authors: YH
authors: Lim
authors: Kyung-Soo
authors: KS
authors: Kim
authors: Soon Gil
authors: SG
authors: Kim
authors: Jeong Hyun
authors: JH
authors: Kim
authors: Heon Kil
authors: HK
authors: Lim
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods; D000368:Aged; D001794:Blood Pressure; D001795:Blood Pressure Determination; D015519:Bone Density; D003430:Cross-Sectional Studies; D005260:Female; D005272:Femur Neck / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000453:epidemiology / Q000378:metabolism; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D010024:Osteoporosis / Q000175:diagnosis / Q000453:epidemiology / Q000378:metabolism; D056910:Republic of Korea / Q000453:epidemiology; D013223:Statistics as Topic
keywords: Bone mineral density; KNHANES; blood pressure; hypertension; osteoporosis