title: Ag shell-Au satellite hetero-nanostructure for ultra-sensitive, reproducible, and homogeneous NIR SERS activity.
abstract: It is critical to create isotropic hot spots in developing a reproducible, homogeneous, and ultrasensitive SERS probe. Here, an Ag shell-Au satellite (Ag-Au SS) nanostructure composed of an Ag shell and surrounding Au nanoparticles was developed as a near-IR active SERS probe. The heterometallic shell-satellite structure based SERS probe produced intense and uniform SERS signals (SERS enhancement factor ∼1.4 × 10(6) with 11% relative standard deviation) with high detectability (100% under current measurement condition) by 785 nm photoexcitation. This signal enhancement was independent of the laser polarizations, which reflects the isotropic feature of the SERS activity of Ag-Au SS from the three-dimensional (3D) distribution of SERS hot spots between the shell and the surrounding satellite particles. The Ag-Au SS nanostructure shows a great potential as a reproducible and quantifiable NIR SERS probe for in vivo targets.
authors: Department of Chemistry Education, and §Interdisciplinary Program in Nano-Science and Technology, #School of Chemical and Biological Engineering, Seoul National University , Seoul 151-742, Republic of Korea.
authors: Hyejin
authors: H
authors: Chang
authors: Homan
authors: H
authors: Kang
authors: Jin-Kyoung
authors: JK
authors: Yang
authors: Ahla
authors: A
authors: Jo
authors: Ho-Young
authors: HY
authors: Lee
authors: Yoon-Sik
authors: YS
authors: Lee
authors: Dae Hong
authors: DH
authors: Jeong
mesh_terms: D000818:Animals; D006046:Gold / Q000737:chemistry*; D021621:Imaging, Three-Dimensional; D008027:Light; D053768:Metal Nanoparticles / Q000737:chemistry; D008670:Metals / Q000737:chemistry; D051379:Mice; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D049329:Nanostructures / Q000737:chemistry; D036103:Nanotechnology / Q000379:methods*; D010316:Particle Size; D015203:Reproducibility of Results; D012542:Scattering, Radiation; D012834:Silver / Q000737:chemistry*; D019265:Spectroscopy, Near-Infrared; D013059:Spectrum Analysis, Raman; D013499:Surface Properties
chemical_list: D008670:Metals; D012834:Silver; D006046:Gold