title: Case Report: Pregnancy in a patient with recurrent glioblastoma.
abstract: We report the case of a woman with relapsed glioblastoma multiforme (GBM) who recently gave birth. She announced her pregnancy shortly after the sixth cycle of a dense regimen of temozolomide, prescribed for treating the first recurrence of glioblastoma. Three years ago, in April 2008, she had undergone gross total resection of a glioblastoma multiforme in the postcentral region of the right hemisphere and had subsequently received treatment according to the actual standard therapy consisting of radiotherapy up to 60 Gy with concomitant and adjuvant temozolomide. The complete amount of temozolomide given before this pregnancy was 20.9 mg/m (2). Nevertheless, she delivered a 1890 g child by caesarean section in the 32/6 week of pregnancy. The child showed no anomalies and is developing normally under close surveillance by paediatricians.
authors: Department of Internal Medicine I, Clinical Division of Oncology, Medical University of Vienna, 1090 Vienna, Austria.
authors: Birgit
authors: B
authors: Flechl
authors: Department of Internal Medicine I, Clinical Division of Oncology, Medical University of Vienna, 1090 Vienna, Austria.
authors: Marco Ronald
authors: MR
authors: Hassler
authors: Department of Internal Medicine I, General Hospital of St. Pölten, 3100 St. Pölten, Austria.
authors: Gerhard
authors: G
authors: Kopetzky
authors: Department of Internal Medicine I, General Hospital of St. Pölten, 3100 St. Pölten, Austria.
authors: Peter
authors: P
authors: Balcke
authors: Department of Obstetrics and Gynaecology, Clinical Division of Endocrinology, Medical University of Vienna, 1090 Vienna, Austria.
authors: Christine
authors: C
authors: Kurz
authors: Department of Internal Medicine I, Clinical Division of Oncology, Medical University of Vienna, 1090 Vienna, Austria ; Comprehensive Cancer Center-Central Nervous System Tumours Unit (CCC-CNS), Medical University of Vienna, 1090 Vienna, Austria.
authors: Christine
authors: C
authors: Marosi