title: Management of prostate cancer in older patients: updated recommendations of a working group of the International Society of Geriatric Oncology.
abstract: In 2010, the International Society of Geriatric Oncology (SIOG) developed treatment guidelines for men with prostate cancer who are older than 70 years old. In 2013, a new multidisciplinary SIOG working group was formed to update these recommendations. The consensus of the task force is that older men with prostate cancer should be managed according to their individual health status, not according to age. On the basis of a validated rapid health status screening instrument and simple assessment, the task force recommends that patients are classed into three groups for treatment: healthy or fit patients who should have the same treatment options as younger patients; vulnerable patients with reversible impairment who should receive standard treatment after medical intervention; and frail patients with non-reversible impairment who should receive adapted treatment.
authors: Claude-Bernard-Lyon-1 University and Department of Medical Oncology, Centre Léon-Bérard, Lyon, France. Electronic address: jpdroz@orange.fr.
authors: Jean-Pierre
authors: JP
authors: Droz
authors: Multidisciplinary Oncology Institute, Clinique de Genolier, Genolier, Switzerland.
authors: Matti
authors: M
authors: Aapro
authors: H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
authors: Lodovico
authors: L
authors: Balducci
authors: Claude-Bernard-Lyon-1 University and Department of Medical Oncology, Centre Léon-Bérard, Lyon, France.
authors: Helen
authors: H
authors: Boyle
authors: Department of Urology, University Hospitals, Leuven, Belgium.
authors: Thomas
authors: T
authors: Van den Broeck
authors: Department of Urology, Queen Mary University of London, London, UK.
authors: Paul
authors: P
authors: Cathcart
authors: Division of Surgery and Interventional Science, University College London, London, UK.
authors: Louise
authors: L
authors: Dickinson
authors: Department of Clinical Therapeutics, University of Athens Medical School, Athens, Greece.
authors: Eleni
authors: E
authors: Efstathiou
authors: Division of Surgery and Interventional Science, University College London, London, UK.
authors: Mark
authors: M
authors: Emberton
authors: Irish Cancer Society and University College Dublin, Dublin, Ireland.
authors: John M
authors: JM
authors: Fitzpatrick
authors: Department of Urology, RWTH University Aachen, Aachen, Germany.
authors: Axel
authors: A
authors: Heidenreich
authors: Guy's and St Thomas' NHS Trust, London, UK.
authors: Simon
authors: S
authors: Hughes
authors: Department of Urology, University Hospitals, Leuven, Belgium.
authors: Steven
authors: S
authors: Joniau
authors: Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA.
authors: Michael
authors: M
authors: Kattan
authors: University Hospital, Saint-Etienne, France.
authors: Nicolas
authors: N
authors: Mottet
authors: Georges Pompidou Hospital, Department of Oncology, Paris, France.
authors: Stéphane
authors: S
authors: Oudard
authors: University College London Hospitals, London, UK.
authors: Heather
authors: H
authors: Payne
authors: Uro‑Oncology Clinic, Centre Hospitalier de l'Université de Montreal, Montreal, QC, Canada.
authors: Fred
authors: F
authors: Saad
authors: Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA.
authors: Toru
authors: T
authors: Sugihara
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000726:Androgen Antagonists / Q000627:therapeutic use; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D018572:Disease-Free Survival; D015577:Geriatric Assessment; D006299:Health Services for the Aged / Q000592:standards; D006801:Humans; D007391:International Cooperation; D008297:Male; D017410:Practice Guidelines as Topic; D011379:Prognosis; D011468:Prostatectomy / Q000379:methods / Q000401:mortality; D011471:Prostatic Neoplasms / Q000401:mortality* / Q000473:pathology / Q000628:therapy*; D020266:Radiotherapy, Conformal / Q000379:methods / Q000401:mortality; D018570:Risk Assessment; D012955:Societies, Medical; D016019:Survival Analysis; D016896:Treatment Outcome; D057832:Watchful Waiting
chemical_list: D000726:Androgen Antagonists; D018931:Antineoplastic Agents, Hormonal