title: Morphofunctional analysis of the prostate exposed to chemical manufacture factors.
abstract: The structural characteristics of the prostate and the blood flow in the organ were studied in chemical plant workers suffering from chronic prostatitis. The prostate echostructure was characterized by vast zones of fibrosis and calcinosis, the hemodynamic ultrasonic parameters were low. Degenerative changes in the acinar structures and stromal fibrosis predominated in the biopsy specimens, these shifts were the most pronounced in the peripheral and transitory zones. Foci of common and small-acinar degeneration of the glands, abundant concrements, and significant collagenization with periglandular and perivascular sclerosis without or with slight inflammatory infiltration were detected. We hypothesize that long exposure to adverse factors of sulfuric acid manufacture contributed to the development of pathological changes in the prostate.
authors: Research Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia, pathol@soramn.ru.
authors: G A
authors: GA
authors: Lapii
authors: L M
authors: LM
authors: Nepomnyashchikh
authors: A V
authors: AV
authors: Kiptilov
authors: A I
authors: AI
authors: Neimark
mesh_terms: D000328:Adult; D000336:Aerosols; D000368:Aged; D000395:Air Pollutants, Occupational / Q000633:toxicity*; D002617:Chemical Industry; D006801:Humans; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D011467:Prostate / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology*; D011472:Prostatitis / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology*; D012039:Regional Blood Flow; D013464:Sulfuric Acids / Q000633:toxicity*; D014463:Ultrasonography; D055815:Young Adult
chemical_list: D000336:Aerosols; D000395:Air Pollutants, Occupational; D013464:Sulfuric Acids; C033158:sulfuric acid