title: Saudi Guidelines on the Diagnosis and Treatment of Pulmonary Hypertension: Pulmonary hypertension due to left heart disease.
abstract: Pulmonary hypertension (PH) due to left heart disease is the most common cause of pulmonary hypertension in the western world. It is classified as WHO PH group II. Different pathophysiologic abnormalities may take place in this condition, including pulmonary venous congestion and vascular remodeling. Despite the high prevalence of WHO group 2 PH, the major focus of research on PH over the past decade has been on WHO group 1 pulmonary arterial hypertension (PAH). Few investigators have focused on WHO group 2 PH; consequently, the pathophysiology of this condition remains poorly understood, and no specific therapy is available. Clinical and translational studies in this area are much needed and have the potential to positively affect large numbers of patients. In this review, we provide a detailed discussion upon the pathophysiology of the disease, the recent updates in classification, and the diagnostic and therapeutic algorithms.
authors: Department of Cardiology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
authors: Waleed
authors: W
authors: Alhabeeb
authors: Pulmonary Medicine, Department of Medicine, Prince Sultan Medical Military City, Riyadh, Kingdom of Saudi Arabia.
authors: Majdy M
authors: MM
authors: Idrees
authors: Department of Cardiology, Fondazione IR IRCCS Policlinico San Matteo, Pavia, Italy.
authors: Stefano
authors: S
authors: Ghio
authors: Department of Cardiac Sciences, King Fahd Cardiac Center, King Saud University, Riyadh, Kingdom of Saudi Arabia.
authors: Tarek
authors: T
authors: Kashour
keywords: Pulmonary hypertension; Saudi association for pulmonary hypertension guidelines; left heart disease; left ventricular end diastolic pressure; pulmonary artery wedge pressure