title: Comparison of a MEMS-Based Handheld OCT Scanner With a Commercial Desktop OCT System for Retinal Evaluation.
abstract: OBJECTIVE
  The goal of this study was to evaluate the ability of our handheld optical coherence tomography (OCT) scanner to image the posterior and anterior structures of the human eye, and especially the individual layers of the retina, and to compare its diagnostic performance with that of a fixed desktop commercial ophthalmic OCT system.
  
  
  METHODS
  We compared the clinical imaging results of our handheld OCT with a leading commercial desktop ophthalmic system (RTVue) used in specialist offices. Six patients exhibiting diabetes-related retinal pathology had both eyes imaged with each OCT system.
  
  
  RESULTS
  In both sets of images, the structural irregularities of the retinal layers could be identified such as retinal edema and vitreomacular traction.
  
  
  CONCLUSIONS
  Our handheld OCT system can be used to identify relevant anatomical structures and pathologies in the eye, potentially enabling earlier screening, disease detection, and treatment. Images can be acquired quickly, with sufficient resolution and negligible motion artifacts that would normally limit its diagnostic use.
  
  
  CONCLUSIONS
  Following screening and early disease detection in primary care via our optimized handheld OCT system, patients can be referred to a specialist for treatment, preventing further disease progression. While many primary care physicians are adept at using the ophthalmoscope, they can definitely take advantage of more advanced technologies.
authors: The Eye Center, Champaign, IL, USA.
authors: Samir I
authors: SI
authors: Sayegh
authors: Beckman Institute for Advanced Science and Technology, Urbana, IL, USA.
authors: Ryan M
authors: RM
authors: Nolan
authors: School of Nano-Bioscience and Chemical Engineering, Ulsan National Institute of Science and Technology, Korea.
authors: Woonggyu
authors: W
authors: Jung
authors: Department of Electrical and Computer Engineering, Kyungpook National University, Korea.
authors: Jeehyun
authors: J
authors: Kim
authors: AdvancedMEMS, San Francisco, CA, USA.
authors: Daniel T
authors: DT
authors: McCormick
authors: Beckman Institute for Advanced Science and Technology, Urbana, IL, USA.
authors: Eric J
authors: EJ
authors: Chaney
authors: Welch Allyn, Inc., Skaneateles Falls, NY, USA.
authors: Charles N
authors: CN
authors: Stewart
authors: Beckman Institute for Advanced Science and Technology, Urbana, IL, USA ; Departments of Electrical and Computer Engineering, Bioengineering, and Internal Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
authors: Stephen A
authors: SA
authors: Boppart
keywords: handheld scanner; microelectromechanical devices; optical coherence tomography