title: Attachment anxiety predicts IL-6 and length of hospital stay in coronary artery bypass graft surgery (CABG) patients.
abstract: OBJECTIVE
  The mechanisms underlying the association between adult attachment and health are not well understood. In the current study, we investigated the relationship between attachment anxiety, attachment avoidance, inflammation, and length of hospital stay in coronary artery bypass graft (CABG) surgery patients.
  
  
  METHODS
  167 CABG patients completed an attachment questionnaire prior to surgery, and blood samples were taken before and after surgery to assess inflammatory activity.
  
  
  RESULTS
  We found that attachment anxiety predicted higher plasma interleukin 6 (IL-6) concentration, and this association was mediated by self-reported sleep quality. Anxious attachment also predicted longer hospital stays following CABG surgery, even after controlling for demographic and clinical factors.
  
  
  CONCLUSIONS
  These data suggest that increased levels of IL-6 may be a process linking adult attachment anxiety with health outcomes.
authors: Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London WC1E 6BT, United Kingdom. Electronic address: T.Kidd@ucl.ac.uk.
authors: Tara
authors: T
authors: Kidd
authors: Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London WC1E 6BT, United Kingdom.
authors: Lydia
authors: L
authors: Poole
authors: Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London WC1E 6BT, United Kingdom.
authors: Elizabeth
authors: E
authors: Leigh
authors: Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London WC1E 6BT, United Kingdom.
authors: Amy
authors: A
authors: Ronaldson
authors: Department of Cardiac Surgery, St. George's Hospital, University of London, Blackshaw Road, London SW17 0QT, United Kingdom.
authors: Marjan
authors: M
authors: Jahangiri
authors: Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London WC1E 6BT, United Kingdom.
authors: Andrew
authors: A
authors: Steptoe
mesh_terms: D000368:Aged; D001007:Anxiety / Q000097:blood / Q000175:diagnosis / Q000209:etiology; D015415:Biomarkers / Q000097:blood; D001026:Coronary Artery Bypass; D005260:Female; D006801:Humans; D007249:Inflammation / Q000097:blood*; D015850:Interleukin-6 / Q000097:blood*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009769:Object Attachment; D006113:United Kingdom
chemical_list: D015415:Biomarkers; D015850:Interleukin-6
keywords: Attachment; CABG; Hospital stay; IL-6; Sleep