title: Aronia melanocarpa treatment and antioxidant status in selected tissues in Wistar rats.
abstract: Aronia juice is considered to be a source of compounds with high antioxidative potential. We conducted a study on the impact of compounds in the Aronia juice on oxidative stress in plasma and brain tissues. The influence of Aronia juice on oxidative stress parameters was tested with the use of a model with a high content of fructose and nonsaturated fats. Therefore, the activity of enzymatic (catalase, CAT, and paraoxonase, PON) and nonenzymatic (thiol groups, SH, and protein carbonyl groups, PCG) oxidative stress markers, which indicate changes in the carbohydrate and protein profiles, was marked in brain tissue homogenates. Adding Aronia caused statistically significant increase in the CAT activity in plasma in all tested diets, while the PON activity showed a statistically significant increase only in case of high fat diet. In animals fed with Aronia juice supplemented with carbohydrates or fat, statistically significant increase in the PON activity and the decrease in the CAT activity in brain tissue were observed. In case of the high fat diet, an increase in the number of SH groups and a decrease in the number of PCG groups in brain tissue were observed.
authors: Department of Bioorganic Chemistry, Medical College, Pharmacy Faculty, Jagiellonian University, 9 Medyczna Street, 30-688 Krakow, Poland ; Institute of Health, State Higher Vocational School, Staszica 1 Street, 33-300 Nowy Sącz, Poland.
authors: Renata
authors: 0000-0002-7071-8072
authors: R
authors: Francik
authors: Department of Food Chemistry and Nutrition, Medical College, Pharmacy Faculty, Jagiellonian University, 9 Medyczna Street, 30-688 Krakow, Poland.
authors: Mirosław
authors: M
authors: Krośniak
authors: Department of Bioorganic Chemistry, Medical College, Pharmacy Faculty, Jagiellonian University, 9 Medyczna Street, 30-688 Krakow, Poland.
authors: Ilona
authors: I
authors: Sanocka
authors: Department of Food Chemistry and Nutrition, Medical College, Pharmacy Faculty, Jagiellonian University, 9 Medyczna Street, 30-688 Krakow, Poland.
authors: Henryk
authors: H
authors: Bartoń
authors: Department of Mechanical Engineering and Agrophysics, Faculty of Production Engineering and Energetics, University of Agriculture in Krakow, 116 B Balicka Street, 30-149 Krakow, Poland.
authors: Tomasz
authors: T
authors: Hebda
authors: Department of Mechanical Engineering and Agrophysics, Faculty of Production Engineering and Energetics, University of Agriculture in Krakow, 116 B Balicka Street, 30-149 Krakow, Poland.
authors: Sławomir
authors: S
authors: Francik
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000737:chemistry*; D043303:Aryldialkylphosphatase / Q000378:metabolism; D001628:Beverages; D001921:Brain / Q000187:drug effects / Q000201:enzymology*; D002374:Catalase / Q000378:metabolism; D005632:Fructose / Q000737:chemistry; D008297:Male; D018384:Oxidative Stress; D046936:Photinia / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar; D013438:Sulfhydryl Compounds / Q000737:chemistry
chemical_list: D000975:Antioxidants; D010936:Plant Extracts; D013438:Sulfhydryl Compounds; D005632:Fructose; D002374:Catalase; D043303:Aryldialkylphosphatase