title: Collagen-based engineered heart muscle.
abstract: Cardiac muscle engineering has evolved over nearly 20 years from a scientific oddity to a mainstream technology with a wide range of applications. Of the many published methods it appears that hydrogels constitute the preferred scaffolds for myocardial tissue engineering and support of organotypic development. Here we describe a simple and highly robust protocol for the generation of engineered heart muscle using a collagen-based hydrogel method.
authors: Institute of Pharmacology, Heart Research Center Göttingen (HRCG), University Medical Center Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany.
authors: Malte
authors: M
authors: Tiburcy
authors: Tim
authors: T
authors: Meyer
authors: Poh Loong
authors: PL
authors: Soong
authors: Wolfram-Hubertus
authors: WH
authors: Zimmermann
mesh_terms: D024042:Collagen Type I / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D009119:Muscle Contraction / Q000187:drug effects; D009206:Myocardium / Q000166:cytology*; D011786:Quality Control; D023822:Tissue Engineering / Q000379:methods*
chemical_list: D024042:Collagen Type I