title: Maternal medical compromise during pregnancy and pregnancy outcomes.
abstract: OBJECTIVE
  To examine the outcomes of pregnancy and newborn following an event of maternal medical compromise during pregnancy.
  
  
  METHODS
  A retrospective study was performed on all patients hospitalized following an event of medical compromise during pregnancy. Medical compromise was divided to acute or chronic bleeding, major or complicated operations, and admission to intensive care unit (ICU). Data collected included maternal, fetal, neonatal and child's follow-up.
  
  
  RESULTS
  The study included 51 pregnant patients and 58 fetuses. The study group had increased risk of preterm deliveries (35.0 versus 6.5%, p < 0.001), cesarean delivery (55.0 versus 22.7%, p < 0.001) and low Apgar scores (5.0 versus 0.45%, p = 0.002). Patients with acute bleeding had higher rates of cesarean sections, preterm deliveries, admissions to neonatal ICU and neonatal mortality. Two cases of fetal abnormalities included brain abnormalities and pericardial effusion. Three terminations of pregnancies were performed: two in patients in ICU due to severe maternal medical condition and one in the fetus with brain abnormalities.
  
  
  CONCLUSIONS
  Maternal medical compromise during pregnancy increases the risk for preterm deliveries, cesarean delivery and low Apgar scores. Acute bleeding was the main cause of medical compromised and with the higher rates of adverse outcomes.
authors: a Department of Obstetrics and Gynecology , The Chaim Sheba Medical Center , Tel HaShomer , Israel .
authors: Alina
authors: A
authors: Weissmann-Brenner
authors: Shimrit
authors: S
authors: Haiman
authors: Maayan-Metzger
authors: MM
authors: Ayala
authors: Liat
authors: L
authors: Gindes
authors: Reuven
authors: R
authors: Achiron
authors: Eyal
authors: E
authors: Sivan
authors: Eran
authors: E
authors: Barzilay
mesh_terms: D000328:Adult; D002585:Cesarean Section / Q000706:statistics & numerical data; D002648:Child; D005260:Female; D006801:Humans; D007223:Infant; D007226:Infant Mortality; D007231:Infant, Newborn; D000068097:Maternal Health; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D011256:Pregnancy Outcome / Q000453:epidemiology*; D047928:Premature Birth / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors
keywords: Cesarean section; maternal medical compromise; pregnancy outcome; premature delivery