title: End-stage kidney disease and kidney transplantation in HIV-positive patients: an observational cohort study.
abstract: End-stage kidney disease (ESKD) is a major complication of HIV infection. We observed a 3.8-fold increase in ESKD prevalence among black patients in the UK CHIC cohort during the 12-year study period. As of 2005, 107 patients had an ESKD diagnosis, 69 of whom (64%) were considered suitable for kidney transplantation (KT) and 34 (32%) had received a KT. Survival was similar for KT recipients and those awaiting KT (85% and 89% at 5 years, respectively; P = 0.53). Our results endorse the use of KT to manage ESKD in HIV-positive patients.
authors: *Department of Renal Sciences, King's College London, London, United Kingdom; †Research Department of Infection and Population Health, University College London, London, United Kingdom; ‡West London Centre for Sexual Health, Chelsea and Westminster Hospital NHS Foundation Trust, London, United Kingdom; §Imperial College Kidney and Transplant Centre, Imperial College Healthcare NHS Trust, London, United Kingdom; ‖UCL Centre for Nephrology, Royal Free Hospital NHS Foundation Trust, London, United Kingdom; ¶Department of Infectious Diseases, The Lothian University Hospitals NHS Trust, Edinburgh, United Kingdom; #Department of Sexual Health and HIV, Brighton and Sussex University Hospitals NHS Trust, Brighton, United Kingdom; and **Department of Sexual Health and HIV, King's College Hospital NHS Foundation Trust, London, United Kingdom.
authors: Esther
authors: E
authors: Gathogo
authors: Sophie
authors: S
authors: Jose
authors: Rachael
authors: R
authors: Jones
authors: Jeremy B
authors: JB
authors: Levy
authors: Nicola E
authors: NE
authors: Mackie
authors: John
authors: J
authors: Booth
authors: John
authors: J
authors: Connolly
authors: Margaret
authors: M
authors: Johnson
authors: Clifford
authors: C
authors: Leen
authors: Debbie
authors: D
authors: Williams
authors: Caroline A
authors: CA
authors: Sabin
authors: Frank A
authors: FA
authors: Post
mesh_terms: D000328:Adult; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D016019:Survival Analysis; D016896:Treatment Outcome; D006113:United Kingdom