title: Effects of intervention to mild GDM on outcomes.
abstract: OBJECTIVE
  To evaluate pregnancy outcomes in women with gestational diabetes mellitus (GDM) diagnosed by the IADPSG criteria at 24-28 weeks of gestation but with fasting plasma glucose (FPG) less than 4.4 mmol/L.
  
  
  METHODS
  A retrospective study was conducted. Medical records of 25,674 pregnant women attending the Peking University First Hospital (PUFH) were analyzed. Women with FPG value <4.4 mmol/L were segregated into those with and without GDM based on the IADPSG criteria. Pregnancy outcomes in the form of birth weight, neonatal hypoglycemia and cesarean delivery were compared between the two groups.
  
  
  RESULTS
  The incidence of macrosomia between GDM 7.1% (treated 6.9%; untreated 7.2%) was not different from the non GDM group 6.3%, similarly neonatal hypoglycemia 1.9% (treated 2.0%; untreated 1.7%) was were not significantly different from the non GDM group 1.1%. Rate of cesarean delivery in the untreated GDM group 59.7% was significantly higher compared to both with treated GDM (48.4%) and the non GDM group (47.6%).
  
  
  CONCLUSIONS
  There is no difference in the incidence of select adverse pregnancy outcomes amongst Chinese women with mild GDM (FPG<4.4 mmol/L) with or without intervention compared to women without GDM.
authors: Department of Obstetrics and Gynecology and.
authors: Yu-Mei
authors: YM
authors: Wei
authors: Hui-Xia
authors: HX
authors: Yang
authors: Wei-Wei
authors: WW
authors: Zhu
authors: Hong-Yun
authors: HY
authors: Yang
authors: Hai-Xia
authors: HX
authors: Li
authors: Anil
authors: A
authors: Kapur
mesh_terms: D000328:Adult; D001724:Birth Weight; D002585:Cesarean Section / Q000706:statistics & numerical data; D016640:Diabetes, Gestational / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D005320:Fetal Macrosomia / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D007003:Hypoglycemia / Q000453:epidemiology / Q000209:etiology; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D015994:Incidence; D007231:Infant, Newborn; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D007004:Hypoglycemic Agents
keywords: Fasting plasma glucose; gestational diabetes mellitus; oral glucose tolerence test