title: Anaplastic large cell lymphoma presenting as a cerebellar mass.
abstract: Anaplastic large cell lymphoma (ALCL) is a T cell lymphoma occurring commonly in childhood and rarely in adults. Central nervous system involvement in ALCL is very rare and cerebellar involvement at presentation has never been described. We examine the case of a young adult who presented with a cerebellar mass. A 19-year-old boy presented with signs of raised intracranial tension, which, on imaging, revealed a right cerebellar mass. He underwent suboccipital craniotomy and partial excision of the tumor. However, the histopathology was inconclusive. He subsequently presented with cerebellar signs and repeat imaging showed recurrence of the cerebellar lesion. He underwent decompression and ventriculoperitoneal (VP) shunting. Histopathology was suggestive of ALK (anaplastic lymphoma kinase) positive anaplastic large cell lymphoma. The patient was started on chemotherapy. However, his neurological status deteriorated, his condition worsened, and he expired a month later.
authors: Department of Medical Oncology, Regional Cancer Centre, Trivandrum 695011, Kerala, India. Electronic address: geenarayanan@yahoo.com.
authors: N
authors: N
authors: Geetha
authors: Department of Medical Oncology, Regional Cancer Centre, Trivandrum 695011, Kerala, India. Electronic address: sreelukp@gmail.com.
authors: K P
authors: KP
authors: Sreelesh
authors: Department of Pathology, Regional Cancer Centre, Trivandrum 695011, India. Electronic address: drrekhanair@gmail.com.
authors: Rekha
authors: R
authors: Nair
authors: Department of Pathology, Regional Cancer Centre, Trivandrum 695011, India. Electronic address: anithamfrancis@gmail.com.
authors: Anitha
authors: A
authors: Mathews
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D017728:Lymphoma, Large-Cell, Anaplastic / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D055815:Young Adult
keywords: ALCL; Brain; Cerebellum; NHL