title: A digital multigate Doppler method for high frequency ultrasound.
abstract: Noninvasive visualization of blood flow with high frequency Doppler ultrasound has been extensively used to assess the morphology and hemodynamics of the microcirculation. A completely digital implementation of multigate pulsed-wave (PW) Doppler method was proposed in this paper for high frequency ultrasound applications. Analog mixer was eliminated by a digital demodulator and the same data acquisition path was shared with traditional B-mode imaging which made the design compact and flexible. Hilbert transform based quadrature demodulation scheme was employed to achieve the multigate Doppler acquisition. A programmable high frequency ultrasound platform was also proposed to facilitate the multigate flow visualization. Experimental results showed good performance of the proposed method. Parabolic velocity gradient inside the vessel and velocity profile with different time slots were acquired to demonstrate the functionality of the multigate Doppler. Slow wall motion was also recorded by the proposed method.
authors: Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China. wb.qiu@siat.ac.cn.
authors: Weibao
authors: W
authors: Qiu
authors: Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China. zy.ye@siat.ac.cn.
authors: Zongying
authors: Z
authors: Ye
authors: Department of Electronic Engineering, City University of Hong Kong, Hong Kong, China. yanyanyu2-c@my.cityu.edu.hk.
authors: Yanyan
authors: Y
authors: Yu
authors: The Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen 518057, China. ap.cheny@connect.polyu.hk.
authors: Yan
authors: Y
authors: Chen
authors: Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China. ly.chi@siat.ac.cn.
authors: Liyang
authors: L
authors: Chi
authors: Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China. pt.mu@siat.ac.cn.
authors: Peitian
authors: P
authors: Mu
authors: Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China. gf.li@siat.ac.cn.
authors: Guofeng
authors: G
authors: Li
authors: Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China. cz.wang@siat.ac.cn.
authors: Congzhi
authors: C
authors: Wang
authors: Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China. yang.xiao@siat.ac.cn.
authors: Yang
authors: Y
authors: Xiao
authors: The Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen 518057, China. jiyan.dai@polyu.edu.hk.
authors: Jiyan
authors: J
authors: Dai
authors: Interdisciplinary Division of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China. lei.sun@polyu.edu.hk.
authors: Lei
authors: L
authors: Sun
authors: Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China. hr.zheng@siat.ac.cn.
authors: Hairong
authors: H
authors: Zheng
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology; D019220:High-Energy Shock Waves; D006801:Humans; D008833:Microcirculation / Q000502:physiology; D014465:Ultrasonics / Q000295:instrumentation* / Q000379:methods*