title: [Oflomelid ointment: activity against hospital microbial strains].
abstract: Ofloxacin susceptibility was tested with the use of 100 hospital isolates by the disk diffusion method vs. the activity of Oflomelid ointment tested by the cavity method. It was shown that the hospital isolates of all the species were susceptible to the Oflomelid ointment, while susceptibility to ofloxacin was preserved in S. epidermidis, the susceptibility of Acinetobacter spp., E. coli, Proteus spp. being intermediate. Such a difference in the susceptibility of the isolates was evidently due to the properties of polyethylene glycols in the ointment composition.
authors: L A
authors: LA
authors: Blatun
authors: R P
authors: RP
authors: Terekhova
mesh_terms: D000150:Acinetobacter / Q000187:drug effects* / Q000254:growth & development / Q000302:isolation & purification; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D003428:Cross Infection / Q000382:microbiology; D052978:Disk Diffusion Antimicrobial Tests; D004926:Escherichia coli / Q000187:drug effects* / Q000254:growth & development / Q000302:isolation & purification; D005079:Excipients / Q000737:chemistry; D006801:Humans; D015242:Ofloxacin / Q000494:pharmacology*; D009824:Ointments / Q000737:chemistry / Q000494:pharmacology*; D011092:Polyethylene Glycols / Q000737:chemistry; D011511:Proteus / Q000187:drug effects* / Q000254:growth & development / Q000302:isolation & purification; D013045:Species Specificity; D013212:Staphylococcus epidermidis / Q000187:drug effects* / Q000254:growth & development / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D005079:Excipients; D009824:Ointments; D011092:Polyethylene Glycols; D015242:Ofloxacin