title: Lumbar discitis caused by Clostridium perfringens.
abstract: We report here a rare case of chronic lumbar discitis caused by Clostridium perfringens in an elderly patient that was treated with a combination of β-lactams and clindamycin. Molecular analysis performed on the strain revealed an unusual toxin gene pattern.
authors: Department of Bacteriology, Nice Academic Hospital, Nice, France Nice Medical University, Nice-Sophia Antipolis University, Nice, France lotte.r@chu-nice.fr.
authors: Romain
authors: R
authors: Lotte
authors: Centre de Référence des Bactéries Anaérobies et du Botulisme, Pasteur Institute, Paris, France.
authors: M R
authors: MR
authors: Popoff
authors: Department of Bacteriology, Nice Academic Hospital, Nice, France.
authors: Nicolas
authors: N
authors: Degand
authors: Department of Bacteriology, Nice Academic Hospital, Nice, France.
authors: Laurene
authors: L
authors: Lotte
authors: Centre de Référence des Bactéries Anaérobies et du Botulisme, Pasteur Institute, Paris, France.
authors: Philippe
authors: P
authors: Bouvet
authors: Department of Radiology, Nice Academic Hospital, Nice, France.
authors: Guillaume
authors: G
authors: Baudin
authors: Department of Infectious Diseases, Nice Academic Hospital, Nice, France.
authors: Eric
authors: E
authors: Cua
authors: Nice Medical University, Nice-Sophia Antipolis University, Nice, France Department of Infectious Diseases, Nice Academic Hospital, Nice, France.
authors: Pierre-Marie
authors: PM
authors: Roger
authors: Department of Bacteriology, Nice Academic Hospital, Nice, France Nice Medical University, Nice-Sophia Antipolis University, Nice, France.
authors: Raymond
authors: R
authors: Ruimy
mesh_terms: D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D001427:Bacterial Toxins / Q000235:genetics; D002981:Clindamycin / Q000627:therapeutic use; D003015:Clostridium Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D003016:Clostridium perfringens / Q000235:genetics / Q000302:isolation & purification*; D015299:Discitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D005260:Female; D005838:Genotype; D006801:Humans; D055959:Intervertebral Disc Degeneration / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D007405:Intervertebral Disc Displacement / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D008826:Microbial Sensitivity Tests; D016133:Polymerase Chain Reaction; D013131:Spine / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed; D047090:beta-Lactams / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D001427:Bacterial Toxins; D047090:beta-Lactams; D002981:Clindamycin