title: [Use of NSAIDs in traumatology].
abstract: In traumatology, non-steroidal anti-inflammatory drugs (NSAIDs) are widely used, due to their efficacy in controlling pain and safety profile. Nonetheless, experimental and retrospective studies about the use of NSAIDs in traumatology raise the question about a possible negative influence on bone remodeling through inhibition of prostaglandin synthesis. The results from these studies must be interpreted with caution, as bone repair can be influenced by several parameters. When used in the case of sprains or tendinitis, unwanted side effects of NSAIDs seem to be limited; on the other hand, benefits in terms of antalgic effect are less clear. We have conducted a review of the literature aimed to suggest practical solutions for the use of NSAIDs in traumatology.
authors: Nicole Ferrera
authors: NF
authors: Espinosa
authors: Brigitte
authors: B
authors: Uebelhart
authors: Sophie
authors: S
authors: Abrassart
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use*; D001842:Bone and Bones / Q000293:injuries; D004363:Drug Utilization; D050723:Fractures, Bone / Q000188:drug therapy; D006801:Humans; D013180:Sprains and Strains / Q000188:drug therapy; D052256:Tendinopathy / Q000188:drug therapy; D014947:Wounds and Injuries / Q000188:drug therapy*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal