title: Heterotopic mesenteric ossification after a ruptured abdominal aortic aneurism: case report with a review of literatures.
abstract: Heterotopic mesenteric ossification (HMO) is a rare disease that results in intra-abdominal ossification of unknown origin. An 88-year-old man developed an intestinal obstruction 2 weeks after undergoing an operation for a ruptured abdominal aortic aneurysm, resulting in intestinal obstructions those did not improved concervatively. During relaparotomy performed 30 days after the first operation, hard adhesions of the small intestine and mesentery were found; these adhesions were difficult to separate without damaging the serosa of the small intestine. We removed 240 cm of the small intestine and performed a jejuno-ileo anastomosis. Microscopically, trabecular bone tissue had increased irregularly in the fat tissue of the nodules with fibrosis, which were partially lined with osteoblasts. Accordingly, we histopathologically diagnosed the patient as having HMO. The patient was treated with NSAIDs and cimetidine to prevent the recurrence of HMO. No signs of recurrence have occurred as of one year after the second operation.
authors: 1 Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
authors: Hiroaki
authors: H
authors: Honjo
authors: Youichi
authors: Y
authors: Kumagai
authors: Toru
authors: T
authors: Ishiguro
authors: Hideko
authors: H
authors: Imaizumi
authors: Tomojiro
authors: T
authors: Ono
authors: Okihide
authors: O
authors: Suzuki
authors: Tetsuya
authors: T
authors: Ito
authors: Norihiro
authors: N
authors: Haga
authors: Kohki
authors: K
authors: Kuwabara
authors: Jun
authors: J
authors: Sobajima
authors: Kensuke
authors: K
authors: Kumamoto
authors: Keiichiro
authors: K
authors: Ishibashi
authors: Hiroyuki
authors: H
authors: Baba
authors: Osamu
authors: O
authors: Sato
authors: Hideyuki
authors: H
authors: Ishida
authors: Hiroyuki
authors: H
authors: Kuwano
mesh_terms: D000369:Aged, 80 and over; D017542:Aneurysm, Ruptured / Q000601:surgery*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D002927:Cimetidine / Q000627:therapeutic use; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology / Q000601:surgery*; D007421:Intestine, Small / Q000601:surgery; D008297:Male; D008643:Mesentery; D009999:Ossification, Heterotopic / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D012086:Reoperation; D000267:Tissue Adhesions / Q000601:surgery
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D006635:Histamine H2 Antagonists; D002927:Cimetidine
keywords: Aortic aneurysm; Heterotopic mesenteric ossification; Ileus; Obstruction; Small bowel