title: Performance evaluation of Samsung LABGEO(HC10) Hematology Analyzer.
abstract: BACKGROUND
  The Samsung LABGEO(HC10) Hematology Analyzer (LABGEO(HC10)) is a recently developed automated hematology analyzer that uses impedance technologies. The analyzer provides 18 parameters including 3-part differential at a maximum rate of 80 samples per hour.
  
  
  OBJECTIVE
  To evaluate the performance of the LABGEO(HC10).
  
  
  METHODS
  We evaluated precision, linearity, carryover, and relationship for complete blood cell count parameters between the LABGEO(HC10) and the LH780 (Beckman Coulter Inc) in a university hospital in Korea according to the Clinical and Laboratory Standards Institute guidelines. Sample stability and differences due to the anticoagulant used (K₂EDTA versus K₃EDTA) were also evaluated.
  
  
  RESULTS
  The LABGEO(HC10) showed linearity over a wide range and minimal carryover (<1%) for white blood cell, hemoglobin, red blood cell, and platelet parameters. Correlation between the LABGEO(HC10) and the LH780 was good for all complete blood cell count parameters (R > 0.92) except for mean corpuscular hemoglobin concentration. The bias estimated was acceptable for all parameters investigated except for monocyte count. Most parameters were stable until 24 hours both at room temperature and at 4°C. The difference by anticoagulant type was statistically insignificant for all parameters except for a few red cell parameters.
  
  
  CONCLUSIONS
  The accurate results achievable and simplicity of operation make the unit recommendable for small to medium-sized laboratories.
authors: From the Department of Laboratory Medicine, Ajou University School of Medicine, Suwon, Republic of Korea.
authors: Il Joong
authors: IJ
authors: Park
authors: Sunhyun
authors: S
authors: Ahn
authors: Young In
authors: YI
authors: Kim
authors: Seon Joo
authors: SJ
authors: Kang
authors: Sung Ran
authors: SR
authors: Cho
mesh_terms: D000925:Anticoagulants / Q000494:pharmacology; D057205:Automation, Laboratory; D001772:Blood Cell Count / Q000295:instrumentation; D001792:Blood Platelets / Q000166:cytology / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D004492:Edetic Acid / Q000494:pharmacology; D017097:Electric Impedance; D004912:Erythrocytes / Q000166:cytology / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D006403:Hematologic Tests / Q000295:instrumentation* / Q000592:standards; D006454:Hemoglobins / Q000032:analysis; D006785:Hospitals, University; D006801:Humans; D008422:Materials Testing; D017410:Practice Guidelines as Topic; D015203:Reproducibility of Results; D056910:Republic of Korea; D013997:Time Factors
chemical_list: D000925:Anticoagulants; D006454:Hemoglobins; D004492:Edetic Acid