title: Novel reversible permanent contraception: an animal experiment of embedding contraceptive surgery in the fimbriated extremity of the fallopian.
abstract: OBJECTIVE
  According to female pelvic anatomical characteristics, we designed a novel reversible permanent contraception: embedding contraceptive surgery in the fimbriated extremity of the fallopian. This study involves embedding the oviduct of New Zealand rabbits into the peritoneum, and assesses contraceptive effect, morphological changes and recoverability.
  
  
  METHODS
  Thirty New Zealand rabbits were divided into three groups: embedding in the fimbriated extremity of the fallopian group (A group); polyethylene film in the fimbriated extremity of the fallopian group (B group); and control (C group). Surgery was performed in each group, respectively. Contraceptive efficacy, morphological changes and recoverability were noted.
  
  
  RESULTS
  As for contraceptive effect, mating experiences were successful. After 3 months, there were no pregnant rabbits in group A and B, while in group C all samples were pregnant. Regarding recoverability, after belly operation, 10 rabbits in group A showed dropsy in the bilateral oviducts. Tissue adhesion could be found in the fimbriated extremity of the fallopian with a large range of damage. All samples in group B also had dropsy, but only two of them had unilateral slight adhesions in the fimbriated extremity of the fallopian, while others had no pathological changes. After being released from the oviduct embedding, five rabbits in group A became pregnant and nine in group B.
  
  
  CONCLUSIONS
  Embedding contraceptive surgery in the fimbriated extremity of the fallopian after being covered by polyethylene film is reliable and safe. Releasing the embedding may cause minor injury. Although there is a problem of hydrosalpinx, the pregnancy rate is high.
authors: Department of Gynecology and Obstetric, The Second Hospital of Shandong University, Jinan, China.
authors: Gang
authors: G
authors: Xin
authors: Juan
authors: J
authors: Du
authors: Jun
authors: J
authors: Zhang
authors: YongPing
authors: Y
authors: Xu
mesh_terms: D000818:Animals; D004487:Edema / Q000209:etiology / Q000517:prevention & control; D005187:Fallopian Tubes / Q000293:injuries / Q000601:surgery; D005260:Female; D005298:Fertility; D010057:Oviducts / Q000293:injuries / Q000601:surgery; D010537:Peritoneum / Q000601:surgery; D011183:Postoperative Complications / Q000517:prevention & control; D011247:Pregnancy; D011817:Rabbits; D013243:Sterilization Reversal / Q000009:adverse effects*; D013246:Sterilization, Tubal; D000267:Tissue Adhesions / Q000517:prevention & control
keywords: fallopian; sterilization; surgical technique