title: [Early detection, prevention and management of renal failure in liver transplantation].
abstract: Renal failure is a frequent complication in liver transplant recipients and is associated with increased morbidity and mortality. A variety of risk factors for the development of renal failure in the pre- and post-transplantation periods have been described, as well as at the time of surgery. To reduce the negative impact of renal failure in this population, an active approach is required for the identification of those patients with risk factors, the implementation of preventive strategies, and the early detection of progressive deterioration of renal function. Based on published evidence and on clinical experience, this document presents a series of recommendations on monitoring RF in LT recipients, as well as on the prevention and management of acute and chronic renal failure after LT and referral of these patients to the nephrologist. In addition, this document also provides an update of the various immunosuppressive regimens tested in this population for the prevention and control of post-transplantation deterioration of renal function.
authors: Servicio de Medicina Interna-Hepatología, Hospital Vall d'Hebron, Barcelona, España; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, España. Electronic address: llcastells@vhebron.net.
authors: Lluís
authors: L
authors: Castells
authors: Servicio del Aparato Digestivo, Instituto de Investigación Biomédica, Hospital Universitario de Bellvitge, Hospitalet de Llobregat, España.
authors: Carme
authors: C
authors: Baliellas
authors: Unidad de Trasplante Hepático, Hospital Vall d'Hebron, Barcelona, España.
authors: Itxarone
authors: I
authors: Bilbao
authors: Servicio de Nefrología, Hospital Vall d'Hebron, Barcelona, España.
authors: Carme
authors: C
authors: Cantarell
authors: Servicio de Nefrología, Hospital Universitario de Bellvitge, Hospitalet de Llobregat, España.
authors: Josep Maria
authors: JM
authors: Cruzado
authors: Unidad de Trasplante Renal, Servicio de Nefrología, Hospital Clínico de Barcelona, Barcelona, España.
authors: Núria
authors: N
authors: Esforzado
authors: Servicio de Trasplante Hepático, Hospital Clínico de Barcelona, Barcelona, España.
authors: Juan Carlos
authors: JC
authors: García-Valdecasas
authors: Unidad de Cirugía Hepática, Hospital Universitario de Bellvitge, Hospitalet de Llobregat, España.
authors: Laura
authors: L
authors: Lladó
authors: Servicio de Hepatología, Hospital Clínico de Barcelona, Barcelona, España.
authors: Antoni
authors: A
authors: Rimola
authors: Servicio de Nefrología, Hospital Vall d'Hebron, Barcelona, España.
authors: Daniel
authors: D
authors: Serón
authors: Unidad de Trasplante Renal, Servicio de Nefrología, Hospital Clínico de Barcelona, Barcelona, España.
authors: Federico
authors: F
authors: Oppenheimer
mesh_terms: D000208:Acute Disease; D000465:Algorithms; D002908:Chronic Disease; D042241:Early Diagnosis; D006801:Humans; D007677:Kidney Function Tests; D016031:Liver Transplantation; D011183:Postoperative Complications / Q000175:diagnosis* / Q000517:prevention & control / Q000628:therapy*; D017410:Practice Guidelines as Topic; D051437:Renal Insufficiency / Q000175:diagnosis* / Q000517:prevention & control / Q000628:therapy*; D012307:Risk Factors
keywords: Everolimus; Inhibidores de la mammalian target of rapamycin; Insuficiencia renal; Liver transplantation; Mammalian target of rapamycin inhibitors; Renal failure; Trasplante hepático