title: [Possibility of DNA isolation from archived autopsy tissues for molecular genetic studies].
abstract: Optimal conditions were defined for DNA isolation from formalin-fixed and paraffin-embedded (FFPE) archived autopsy lung tissue slices. The quality of DNA preparations isolated from the FFPE archived slices was assessed and their suitability for further molecular genetic analysis estimated. DNA isolated from the FFPE slices stored less and more than 10 years was suitable for molecular genetic studies in 100 and 66.7% of cases, respectively.
authors: N S
authors: NS
authors: Viazovskaia
authors: G G
authors: GG
authors: Rusinova
authors: T V
authors: TV
authors: Azizova
authors: V S
authors: VS
authors: Revina
authors: I V
authors: IV
authors: Glazkova
authors: E V
authors: EV
authors: Generozov
authors: N B
authors: NB
authors: Zakharzhevskaia
authors: D S
authors: DS
authors: Matushkina
mesh_terms: D001344:Autopsy; D004247:DNA / Q000235:genetics* / Q000302:isolation & purification*; D005557:Formaldehyde; D006801:Humans; D008168:Lung / Q000737:chemistry / Q000473:pathology; D016612:Paraffin Embedding; D016707:Tissue Fixation
chemical_list: D005557:Formaldehyde; D004247:DNA