title: Narrowband ultraviolet B phototherapy in combination with other therapies for vitiligo: mechanisms and efficacies.
abstract: Vitiligo is a disorder of pigmentation affecting about 1% of the global population. It is a psychologically devastating disease with suboptimal treatment options. Narrowband ultraviolet B (NB-UVB) phototherapy has become a first-line choice for treating generalized disease. In recent years, topical calcineurin inhibitors, vitamin D analogues, antioxidant agents and other therapies have been combined with NB-UVB to improve its efficacy. This article will address what is known about the mechanisms of action of these treatments and how they may complement NB-UVB on a cellular level, as well as offer a comprehensive, evidence-based review of clinical outcomes with combination therapies.
authors: Department of Dermatology and Cutaneous Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, FL, 33136, USA.
authors: M
authors: M
authors: Yazdani Abyaneh
authors: R D
authors: RD
authors: Griffith
authors: L
authors: L
authors: Falto-Aizpurua
authors: K
authors: K
authors: Nouri
mesh_terms: D006801:Humans; D010789:Phototherapy; D014466:Ultraviolet Rays; D014820:Vitiligo / Q000628:therapy*