title: [Bone dysplasia in mucopolysacchoridoses].
abstract: Mucopolysaccharidoses (MPS) are a group of disorders characterized by the accumulation of glycosaminoglycans. Skeletal abnormalities are early and prominent features of MPS. Cervical spine and atlantoaxial instability, thoracolumbar kyphosis, hip dysplasia and osteonecrosis, genu valgum, and carpal tunnel syndrome are frequently observed. MPS disease-awareness is important for pediatric healthcare providers who should be able to recognize the clinical presentation, musculoskeletal abnormalities, and radiographic findings associated with this group of disorders.
authors: Service d'orthopédie et traumatologie infantile, CHU de Nancy, hôpital d'enfants de Brabois, rue du Morvan, 54500 Vandœuvre-lès-Nancy, France. Electronic address: p.journeau@chu-nancy.fr.
authors: P
authors: P
authors: Journeau
authors: Service d'orthopédie et traumatologie pédiatrique, CHU de Lyon, hôpital Femme-Mère-Enfant, 59, boulevard Pinel, 69677 Bron cedex, France.
authors: C
authors: C
authors: Garin
authors: Service d'orthopédie et traumatologie infantile, CHU de Nancy, hôpital d'enfants de Brabois, rue du Morvan, 54500 Vandœuvre-lès-Nancy, France.
authors: E
authors: E
authors: Polirsztok
authors: Service d'orthopédie pédiatrique, CHU de Marseille, hôpital La Timone, 264, rue Saint-Pierre, 13385 Marseille cedex, France.
authors: J-L
authors: JL
authors: Jouve
mesh_terms: D001848:Bone Diseases, Developmental / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D002648:Child; D006801:Humans; D009083:Mucopolysaccharidoses / Q000150:complications* / Q000175:diagnosis / Q000628:therapy