title: Performance monitoring during associative learning and its relation to obsessive-compulsive characteristics.
abstract: Neural responses to performance errors and external feedback have been suggested to be altered in obsessive-compulsive disorder. In the current study, an associative learning task was used in healthy participants assessed for obsessive-compulsive symptoms by the OCI-R questionnaire. The task included a condition with equivocal feedback that did not inform about the participants' performance. Following incorrect responses, an error-related negativity and an error positivity were observed. In the feedback phase, the largest feedback-related negativity was observed following equivocal feedback. Theta and beta oscillatory components were found following incorrect and correct responses, respectively, and an increase in theta power was associated with negative and equivocal feedback. Changes over time were also explored as an indicator for possible learning effects. Finally, event-related potentials and oscillatory components were found to be uncorrelated with OCI-R scores in the current non-clinical sample.
authors: Department of Neurology, Universität zu Lübeck, Germany. Electronic address: nuria.donamayor@neuro.uni-luebeck.de.
authors: Nuria
authors: N
authors: Doñamayor
authors: Department of Neurology, Universität zu Lübeck, Germany.
authors: Jakob
authors: J
authors: Dinani
authors: Department of Neurology, Universität zu Lübeck, Germany.
authors: Manuel
authors: M
authors: Römisch
authors: Donders Centre for Cognitive Neuroimaging, Radboud Universiteit Nijmegen, The Netherlands.
authors: Zheng
authors: Z
authors: Ye
authors: Department of Neurology, Universität zu Lübeck, Germany.
authors: Thomas F
authors: TF
authors: Münte
mesh_terms: D000328:Adult; D001245:Association Learning / Q000502:physiology*; D003214:Conditioning, Classical / Q000502:physiology*; D004569:Electroencephalography; D005071:Evoked Potentials / Q000502:physiology*; D005246:Feedback; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000503:physiopathology*; D055815:Young Adult
keywords: Electroencephalography; Error-related negativity; Feedback-related negativity; Obsessive-compulsive disorder; Reinforcement learning