title: Synthesis of multisubstituted 2-aminopyrroles/pyridines via chemoselective Michael addition/intramolecular cyclization reaction.
abstract: A facile and efficient synthetic strategy to construct polysubstituted 2-aminopyrroles/pyridines was developed via chemoselective Michael addition/intramolecular cyclization reaction under very mild conditions. It suggested that the chemoselectivity of the process could be controlled by the leaving ability of the halides.
authors: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , 555 Zuchongzhi Road, Shanghai, 201203, China.
authors: Xueyu
authors: X
authors: Qi
authors: Haoyue
authors: H
authors: Xiang
authors: Qian
authors: Q
authors: He
authors: Chunhao
authors: C
authors: Yang
mesh_terms: D002384:Catalysis; D003500:Cyclization; D015394:Molecular Structure; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D011725:Pyridines; D011758:Pyrroles