title: IQuant: an automated pipeline for quantitative proteomics based upon isobaric tags.
abstract: Quantitative proteomics technology based on isobaric tags is playing an important role in proteomic investigation. In this paper, we present an automated software, named IQuant, which integrates a postprocessing tool of protein identification and advanced statistical algorithms to process the MS/MS signals generated from the peptides labeled by isobaric tags and aims at proteomics quantification. The software of IQuant, which is freely downloaded at http://sourceforge.net/projects/iquant/, can run from a graphical user interface and a command-line interface, and can work on both Windows and Linux systems.
authors: BGI-Shenzhen, Shenzhen, P. R. China.
authors: Bo
authors: B
authors: Wen
authors: Ruo
authors: R
authors: Zhou
authors: Qiang
authors: Q
authors: Feng
authors: Quanhui
authors: Q
authors: Wang
authors: Jun
authors: J
authors: Wang
authors: Siqi
authors: S
authors: Liu
mesh_terms: D020407:Internet; D010455:Peptides / Q000032:analysis; D011506:Proteins / Q000032:analysis; D040901:Proteomics / Q000379:methods*; D012984:Software; D053719:Tandem Mass Spectrometry / Q000379:methods*
chemical_list: D010455:Peptides; D011506:Proteins
keywords: Bioinformatics; Isobaric tags; Mass spectrometry; Protein quantification; Technology