title: Electromagnetic thermotherapy for deep organ ablation by using a needle array under a synchronized-coil system.
abstract: Thermal ablation by using electromagnetic thermotherapy (EMT) has been a promising cancer modality in recent years. It has relatively few side effects and has therefore been extensively investigated for a variety of medical applications in internal medicine and surgery. The EMT system applies a high-frequency alternating electromagnetic field to heat up the needles which are inserted into the target tumor to cause tumor ablation. In this study, a new synchronized-coil EMT system was demonstrated, which was equipped with two synchronized coils and magnetic field generators to provide a long-range, penetrated electromagnetic field to effectively heat up the needles. The heating effect of the needles at the center of the two coils was first explored. The newly designed two-section needle array combined with the synchronized-coil EMT system was thus demonstrated in the in vitro and in vivo animal experiments. Experimental data showed that the developed system is promising for minimally invasive surgery since it might provide superior performance for thermotherapy in cancer treatment.
authors: Sheng-Chieh
authors: SC
authors: Huang
authors: Jui-Wen
authors: JW
authors: Kang
authors: Hung-Wen
authors: HW
authors: Tsai
authors: Yan-Shen
authors: YS
authors: Shan
authors: Xi-Zhang
authors: XZ
authors: Lin
authors: Gwo-Bin
authors: GB
authors: Lee
mesh_terms: D055011:Ablation Techniques / Q000295:instrumentation* / Q000379:methods; D000818:Animals; D004574:Electromagnetic Fields; D004867:Equipment Design; D006979:Hyperthermia, Induced / Q000295:instrumentation*; D008099:Liver / Q000473:pathology / Q000528:radiation effects / Q000601:surgery; D009339:Needles; D013552:Swine