title: Levofloxacin-resistant haemophilus influenzae, Taiwan, 2004-2010.
abstract: Levofloxacin resistance in Haemophilus influenzae has increased significantly in Taiwan, from 2.0% in 2004 to 24.3% in 2010 (p<0.001). Clinical and molecular investigations of 182 levofloxacin-resistant isolates revealed that the increase was mainly the result of the spread of several clones in the elderly population in different regions.
authors: Shu-Chen
authors: SC
authors: Kuo
authors: Pei-Chen
authors: PC
authors: Chen
authors: Yih-Ru
authors: YR
authors: Shiau
authors: Hui-Ying
authors: HY
authors: Wang
authors: Jui-Fen
authors: JF
authors: Lai
authors: Wen
authors: W
authors: Huang
authors: Tsai-Ling Yang
authors: TL
authors: Lauderdale
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D016000:Cluster Analysis; D003428:Cross Infection; D024881:Drug Resistance, Bacterial; D016521:Electrophoresis, Gel, Pulsed-Field; D006192:Haemophilus Infections / Q000453:epidemiology* / Q000266:history / Q000382:microbiology*; D006193:Haemophilus influenzae / Q000145:classification / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D049674:History, 21st Century; D006801:Humans; D064704:Levofloxacin / Q000494:pharmacology*; D008875:Middle Aged; D058885:Multilocus Sequence Typing; D062486:Public Health Surveillance; D013624:Taiwan / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents; D064704:Levofloxacin
keywords: GyrA; Haemophilus influenzae; ParC; Taiwan; antimicrobial resistance; bacteria; fluoroquinolone resistance; levofloxacin; respiratory infections