title: Antimicrobial activity of cobalt imidazolate metal-organic frameworks.
abstract: Two cobalt imidazolate metal-organic frameworks were evaluated as a bactericidal material against the growth of the Gram-negative bacteria Pseudomonas putida and Escherichia coli. Under the most unfavourable conditions, within the exponential growth phase and in the culture media for both microorganisms, the growth inhibition reached over 50% for concentrations of biocidal material in the 5-10mgL(-1) range. The release of metal gives excellent durability with the antibacterial effect persisting after 3months. Both cobalt-based materials can be prepared with simple, cheap and easily accessible commercial ligands, leading to a more affordable possible future application as antimicrobial materials.
authors: Department of Chemical Engineering, University of Alcalá, 28871 Alcalá de Henares, Madrid, Spain. Electronic address: sonia.aguado@uah.es.
authors: Sonia
authors: S
authors: Aguado
authors: Department of Chemical Engineering, University of Alcalá, 28871 Alcalá de Henares, Madrid, Spain.
authors: Jennifer
authors: J
authors: Quirós
authors: Institut de Recherches sur la Catalyse et l'Environnement de Lyon (IRCELYON), University Lyon 1, CNRS; 2, Avenue Albert Einstein, 69626 Villeurbanne, France.
authors: Jerome
authors: J
authors: Canivet
authors: Institut de Recherches sur la Catalyse et l'Environnement de Lyon (IRCELYON), University Lyon 1, CNRS; 2, Avenue Albert Einstein, 69626 Villeurbanne, France.
authors: David
authors: D
authors: Farrusseng
authors: Department of Chemical Engineering, University of Alcalá, 28871 Alcalá de Henares, Madrid, Spain.
authors: Karina
authors: K
authors: Boltes
authors: Department of Chemical Engineering, University of Alcalá, 28871 Alcalá de Henares, Madrid, Spain.
authors: Roberto
authors: R
authors: Rosal
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D003035:Cobalt / Q000737:chemistry / Q000494:pharmacology*; D003470:Culture Media; D004926:Escherichia coli / Q000187:drug effects; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D007093:Imidazoles / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry / Q000494:pharmacology*; D016958:Pseudomonas putida / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D003470:Culture Media; D007093:Imidazoles; D009942:Organometallic Compounds; D003035:Cobalt
keywords: Antibacterial; Cobalt; Escherichia coli; Metal organic frameworks