title: Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential.
abstract: Some protein pharmaceuticals from Chinese medicine have been developed to treat cardiovascular diseases, genetic diseases, and cancer. Bioactive proteins with various pharmacological properties have been successfully isolated from animals such as Hirudo medicinalis (medicinal leech), Eisenia fetida (earthworm), and Mesobuthus martensii (Chinese scorpion), and from herbal medicines derived from species such as Cordyceps militaris, Ganoderma, Momordica cochinchinensis, Viscum album, Poria cocos, Senna obtusifolia, Panax notoginseng, Smilax glabra, Ginkgo biloba, Dioscorea batatas, and Trichosanthes kirilowii. This article reviews the isolation methods, molecular characteristics, bioactivities, pharmacological properties, and potential uses of bioactive proteins originating from these Chinese medicines.
authors: School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, China.
authors: Kam Lok
authors: KL
authors: Wong
authors: Department of Biology, Faculty of Science, Hong Kong Baptist University, Hong Kong Special Administrative Region, China.
authors: Ricky Ngok Shun
authors: RN
authors: Wong
authors: School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, China.
authors: Liang
authors: L
authors: Zhang
authors: School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong Special Administrative Region, China.
authors: Wing Keung
authors: WK
authors: Liu
authors: School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong Special Administrative Region, China.
authors: Tzi Bun
authors: TB
authors: Ng
authors: School of Life Sciences and Centre for Protein Science and Crystallography, Faculty of Science, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong Special Administrative Region, China.
authors: Pang Chui
authors: PC
authors: Shaw
authors: Department of Pharmacology & Pharmacy, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
authors: Philip Chi Lip
authors: PC
authors: Kwok
authors: Department of Health Technology and Informatics, Hong Kong Polytechnic University, Hung Hom, Hong Kong Special Administrative Region, China.
authors: Yau Ming
authors: YM
authors: Lai
authors: School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, China.
authors: Zhang Jin
authors: ZJ
authors: Zhang
authors: School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, China.
authors: Yanbo
authors: Y
authors: Zhang
authors: School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, China.
authors: Yao
authors: Y
authors: Tong
authors: School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, China.
authors: Ho-Pan
authors: HP
authors: Cheung
authors: School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, China.
authors: Jia
authors: J
authors: Lu
authors: School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, China.
authors: Stephen Cho Wing
authors: SC
authors: Sze