title: Systemic gene silencing in plants triggered by fluorescent nanoparticle-delivered double-stranded RNA.
abstract: A cationic fluorescence nanoparticle efficiently enters plants with high transfection efficacy. Applying a mixture of G2/dsRNA to the model plant, Arabidopsis root, leads to significant reduction in the expression of important developmental genes and results in apparent phenotypes. This study reports a non-viral gene nanocarrier which triggers gene silencing in plants and leads to systemic phenotypes.
authors: College of Agronomy and Biotechnology, Beijing Key Laboratory of Growth and Developmental Regulation for Protected Vegetable Crops, China Agricultural University, Beijing 100193, China. shenjie@cau.edu.cn zhxiaolan@cau.edu.cn.
authors: Li
authors: L
authors: Jiang
authors: Lian
authors: L
authors: Ding
authors: Bicheng
authors: B
authors: He
authors: Jie
authors: J
authors: Shen
authors: Zejun
authors: Z
authors: Xu
authors: Meizhen
authors: M
authors: Yin
authors: Xiaolan
authors: X
authors: Zhang
mesh_terms: D017360:Arabidopsis / Q000166:cytology / Q000235:genetics*; D005456:Fluorescent Dyes / Q000737:chemistry*; D008422:Materials Testing; D053769:Nanocapsules / Q000008:administration & dosage / Q000737:chemistry* / Q000648:ultrastructure; D010316:Particle Size; D030821:Plants, Genetically Modified / Q000235:genetics; D034622:RNA Interference; D012330:RNA, Double-Stranded / Q000008:administration & dosage / Q000235:genetics*; D013499:Surface Properties; D014162:Transfection / Q000379:methods*
chemical_list: D005456:Fluorescent Dyes; D053769:Nanocapsules; D012330:RNA, Double-Stranded