title: Role of NF-κB-dependent signaling in the growth capacity of mesenchymal progenitor cells under the influence of basic fibroblast growth factor.
abstract: We studied the in vitro role of NF-κB-dependent signaling in the growth capacity of mesenchymal progenitor cells upon stimulation by basic fibroblast growth factor. Proliferative activity of progenitor cells was suppressed by specifi c inhibitors of this transcription factor (NF-κB), oridonin and aurothiomalate. These inhibitors had no effect on differentiation of fibroblast CFU.
authors: Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia, zgn@pharm.tsu.ru.
authors: G N
authors: GN
authors: Zyuz'kov
authors: M G
authors: MG
authors: Danilets
authors: A A
authors: AA
authors: Ligacheva
authors: V V
authors: VV
authors: Zhdanov
authors: E V
authors: EV
authors: Udut
authors: L A
authors: LA
authors: Miroshnichenko
authors: A V
authors: AV
authors: Chaikovskii
authors: E V
authors: EV
authors: Simanina
authors: E S Trofi
authors: ES
authors: Mova
authors: M Yu
authors: MY
authors: Minakova
authors: E A
authors: EA
authors: Losev
authors: V V
authors: VV
authors: Udut
authors: A M
authors: AM
authors: Dygai
mesh_terms: D000818:Animals; D059447:Cell Cycle Checkpoints; D049109:Cell Proliferation; D002478:Cells, Cultured; D016222:Fibroblast Growth Factor 2 / Q000502:physiology*; D059630:Mesenchymal Stem Cells / Q000502:physiology*; D008808:Mice, Inbred CBA; D016328:NF-kappa B / Q000378:metabolism*; D015290:Second Messenger Systems
chemical_list: D016328:NF-kappa B; D016222:Fibroblast Growth Factor 2