title: Purple glove syndrome occurring after oral administration of phenytoin in therapeutic doses: mechanism still a dilemma.
abstract: Purple glove syndrome is a rare and poorly understood complication of phenytoin use, occurring almost always with its intravenous formulation. This syndrome comprises of pain, purple discoloration, and edema distal to the site of intravenous administration of phenytoin. We hereby report an unusual case, wherein purple glove syndrome was seen on oral formulation of phenytoin in its therapeutic dose.
authors: Department of Neurology, SMS Medical College, Jaipur, Rajasthan, India. Electronic address: drrsjain@yahoo.com.
authors: Rajendra Singh
authors: RS
authors: Jain
authors: Department of Neurology, SMS Medical College, Jaipur, Rajasthan, India. Electronic address: kadamnagpal@gmail.com.
authors: Kadam
authors: K
authors: Nagpal
authors: Department of Neurology, SMS Medical College, Jaipur, Rajasthan, India. Electronic address: doc.kumarsunil@hotmail.com.
authors: Sunil
authors: S
authors: Kumar
authors: Department of Neurology, SMS Medical College, Jaipur, Rajasthan, India. Electronic address: vanswayam@rediffmail.com.
authors: Swayam
authors: S
authors: Prakash
authors: Department of Neurology, SMS Medical College, Jaipur, Rajasthan, India. Electronic address: pratibha_doc2000@yahoo.co.in.
authors: Rahul
authors: R
authors: Handa
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage* / Q000009:adverse effects*; D003490:Cyanosis / Q000139:chemically induced*; D004487:Edema / Q000139:chemically induced*; D006225:Hand; D006801:Humans; D008297:Male; D010672:Phenytoin / Q000008:administration & dosage* / Q000009:adverse effects*; D013226:Status Epilepticus / Q000188:drug therapy*; D013577:Syndrome
chemical_list: D000927:Anticonvulsants; D010672:Phenytoin