title: Self-rated and assessed cognitive functions in epilepsy: impact on quality of life.
abstract: OBJECTIVE
  To compare the effects of perceived and assessed cognitive functions on quality of life (QoL) in patients with epilepsy (PWE).
  
  
  METHODS
  The study analyzed the data from a series of PWE who compiled the Quality of Life in Epilepsy-89 Inventory (QOLIE-89) and the Multiple Ability Self-Report Questionnaire (MASQ) for QoL and perceived cognitive abilities, respectively. The State-Trait Anxiety and Beck Depression inventories were used to assess mood. Neuropsychological tests evaluated abstract reasoning, attention, conceptual-motor tracking, constructional praxis, language, verbal and non-verbal memory, abstraction, category shifting, verbal fluency, and visual-spatial abilities.
  
  
  RESULTS
  The QOLIE-89 overall score was predicted by the Mood and Attention and Executive Functions factors and MASQ scores, explaining 38, 6, and 4% of its variance, while disease duration, seizure frequency, and schooling determined 16%. The QOLIE-89 Psychosocial, Cognitive, and Physical Performance sub-domains related to mood. The Cognitive and Physical Performance factors also related to the MASQ and Attention and Executive Functions factor scores, respectively.
  
  
  CONCLUSIONS
  In PWE, self-rated and assessed cognitive deficits may influence QoL, explaining 10% of its variance irrespective from mood and clinical variables. Treating cognitive deficits and their perception may help improve QoL.
authors: Department of Diagnostics and Applied Technology, Fondazione IRCCS Istituto Neurologico C. Besta, Milano, Italy. Electronic address: annarita.giovagnoli@gmail.com.
authors: Anna Rita
authors: AR
authors: Giovagnoli
authors: Department of Diagnostics and Applied Technology, Fondazione IRCCS Istituto Neurologico C. Besta, Milano, Italy.
authors: Annalisa
authors: A
authors: Parente
authors: Department of Diagnostics and Applied Technology, Fondazione IRCCS Istituto Neurologico C. Besta, Milano, Italy.
authors: Anna
authors: A
authors: Tarallo
authors: Department of Diagnostics and Applied Technology, Fondazione IRCCS Istituto Neurologico C. Besta, Milano, Italy.
authors: Marina
authors: M
authors: Casazza
authors: Department of Diagnostics and Applied Technology, Fondazione IRCCS Istituto Neurologico C. Besta, Milano, Italy.
authors: Silvana
authors: S
authors: Franceschetti
authors: Department of Diagnostics and Applied Technology, Fondazione IRCCS Istituto Neurologico C. Besta, Milano, Italy.
authors: Giuliano
authors: G
authors: Avanzini
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003071:Cognition; D004827:Epilepsy / Q000175:diagnosis / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011788:Quality of Life / Q000523:psychology*; D012189:Retrospective Studies; D057566:Self Report; D055815:Young Adult
keywords: Cognitive deficits; Epilepsy; Neuropsychology; Quality of life; Self-rating