title: Myorelaxant effect of bee venom topical skin application in patients with RDC/TMD Ia and RDC/TMD Ib: a randomized, double blinded study.
abstract: The aim of the study was the evaluation of myorelaxant action of bee venom (BV) ointment compared to placebo. Parallel group, randomized double blinded trial was performed. Experimental group patients were applying BV for 14 days, locally over masseter muscles, during 3-minute massage. Placebo group patients used vaseline for massage. Muscle tension was measured twice (TON1 and TON2) in rest muscle tonus (RMT) and maximal muscle contraction (MMC) on both sides, right and left, with Easy Train Myo EMG (Schwa-medico, Version 3.1). Reduction of muscle tonus was statistically relevant in BV group and irrelevant in placebo group. VAS scale reduction was statistically relevant in both groups: BV and placebo. Physiotherapy is an effective method for myofascial pain treatment, but 0,0005% BV ointment gets better relief in muscle tension reduction and analgesic effect. This trial is registered with Clinicaltrials.gov NCT02101632.
authors: Department of Orthodontics and Temporomandibular Joint Dysfunction, Medical University of Silesia in Katowice, plac Traugutta 2, 41-800 Zabrze, Poland.
authors: Aleksandra
authors: 0000-0002-0322-2130
authors: A
authors: Nitecka-Buchta
authors: Department of Orthodontics and Temporomandibular Joint Dysfunction, Medical University of Silesia in Katowice, plac Traugutta 2, 41-800 Zabrze, Poland.
authors: Piotr
authors: 0000-0001-8725-000X
authors: P
authors: Buchta
authors: Department of Orthodontics and Temporomandibular Joint Dysfunction, Medical University of Silesia in Katowice, plac Traugutta 2, 41-800 Zabrze, Poland.
authors: Elżbieta
authors: 0000-0001-9857-3170
authors: E
authors: Tabeńska-Bosakowska
authors: Department of Orthodontics and Temporomandibular Joint Dysfunction, Medical University of Silesia in Katowice, plac Traugutta 2, 41-800 Zabrze, Poland.
authors: Karolina
authors: 0000-0003-3066-7765
authors: K
authors: Walczyńska-Dragoń
authors: Department of Orthodontics and Temporomandibular Joint Dysfunction, Medical University of Silesia in Katowice, plac Traugutta 2, 41-800 Zabrze, Poland.
authors: Stefan
authors: S
authors: Baron
mesh_terms: D000287:Administration, Topical; D000328:Adult; D001514:Bee Venoms / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use*; D004311:Double-Blind Method; D004576:Electromyography; D005260:Female; D006801:Humans; D008297:Male; D008406:Masseter Muscle / Q000187:drug effects / Q000502:physiology; D009126:Muscle Relaxation / Q000187:drug effects*; D009129:Muscle Tonus / Q000187:drug effects / Q000502:physiology; D010147:Pain Measurement; D010919:Placebos; D012146:Rest / Q000502:physiology; D012867:Skin / Q000187:drug effects*; D013705:Temporomandibular Joint Disorders / Q000188:drug therapy* / Q000503:physiopathology*; D055815:Young Adult
chemical_list: D001514:Bee Venoms; D010919:Placebos