title: Trifluoromethylation of arenediazonium salts with fluoroform-derived CuCF3 in aqueous media.
abstract: A new protocol has been developed for trifluoromethylation of arenediazonium salts with moisture-sensitive CuCF3 (from fluoroform) in aqueous media. The reaction is governed by a radical mechanism, tolerates a broad variety of functional groups, and is applicable to the synthesis of complex, polyfunctionalized molecules.
authors: Institute of Chemical Research of Catalonia (ICIQ), Avgda. Països Catalans 16, 43007 Tarragona, Spain. vgrushin@iciq.es.
authors: Anton
authors: A
authors: Lishchynskyi
authors: Guillaume
authors: G
authors: Berthon
authors: Vladimir V
authors: VV
authors: Grushin
mesh_terms: D005617:Chlorofluorocarbons, Methane / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D018360:Crystallography, X-Ray; D003979:Diazonium Compounds / Q000737:chemistry*; D008745:Methylation; D014867:Water / Q000737:chemistry*
chemical_list: D005617:Chlorofluorocarbons, Methane; D003979:Diazonium Compounds; D014867:Water; D003300:Copper; C009554:fluoroform