title: Short-term changes of intraocular pressure after cervical interlaminar epidural injection: a pilot study.
abstract: BACKGROUND
  Cervical epidural injection (CEI) is widely performed on patients with intervertebral disc herniation. The aim of the present study was to investigate the short-term effects of CEI on non-invasive intraocular pressure (IOP) measurements in subjects with normal eyes.
  
  
  METHODS
  This prospective study enrolled 15 patients who were undergoing CEI at the C5/6 level with an interlaminar approach in the left lateral decubitus position. IOP was measured in both eyes by a rebound tonometer (Icare-PRO, Icare Finland Oy, Helsinki, Finland). A total volume of 14 ml (4 ml non-ionic contrast, a mixture of 0.2% lidocaine 1 ml and normal saline 4 ml for irrigation and a mixture of normal saline 4.5 ml with non-particulate betamethasone 2 mg) was injected with 1.0 ml s(-1). IOP was measured 5 min after the lateral decubitus position (T0, baseline), immediately after CEI (T1), and 1 min intervals for 5 min (T2-T6).
  
  
  RESULTS
  The values of left and right baseline IOP (T0) were 18.9 (2.0) and 15.6 (2.6) mm Hg, respectively. IOP of left and right eyes at T1 [26.6 (4.2) and 21.2 (2.5) mm Hg, respectively] and T2 [26.2 (4.5) and 21.0 (2.8) mm Hg, respectively] were significantly higher compared with T0. These values immediately decreased at T3 and returned to baseline levels within 5 min after CEI.
  
  
  CONCLUSIONS
  CEI resulted in an elevation of IOP of both eyes. However, the effects were transient only lasting a few minutes.
authors: Department of Anesthesiology and Pain Medicine and.
authors: S S
authors: SS
authors: Kang
authors: Department of Anesthesiology and Pain Medicine and.
authors: I S
authors: IS
authors: Kim
authors: Department of Anesthesiology and Pain Medicine and.
authors: J H
authors: JH
authors: Park
authors: Department of Anesthesiology and Pain Medicine and.
authors: S J
authors: SJ
authors: Hong
authors: Department of Anesthesiology and Pain Medicine and.
authors: H K
authors: HK
authors: Shin
authors: Department of Anesthesiology and Pain Medicine and.
authors: C G
authors: CG
authors: Song
authors: Department of Ophthalmology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, 445, Gil-dong, Gangdong-gu, Seoul 134-010, Republic of Korea demian7435@gmail.com paintx@naver.com.
authors: Y C
authors: YC
authors: Yoo
authors: Department of Anesthesiology and Pain Medicine and demian7435@gmail.com paintx@naver.com.
authors: K M
authors: KM
authors: Shin
mesh_terms: D000328:Adult; D000368:Aged; D000556:Ambulatory Surgical Procedures; D000767:Anesthesia, Epidural / Q000009:adverse effects*; D000779:Anesthetics, Local / Q000008:administration & dosage; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000601:surgery; D007429:Intraocular Pressure / Q000187:drug effects*; D008012:Lidocaine / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D019547:Neck Pain / Q000150:complications; D056888:Patient Positioning; D010865:Pilot Projects; D011446:Prospective Studies; D055815:Young Adult
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine
keywords: analgesic techniques, epidural; epidural; eye, intraocular pressure