title: Recommendations of the Alzheimer's disease-related dementias conference.
abstract: The National Alzheimer's Project Act, signed into law in 2011, mandates a National Plan to Address Alzheimer's Disease that is updated annually. In the Plan, the term Alzheimer disease includes not only Alzheimer disease (AD) proper, but also several specified related dementias, namely, frontotemporal, Lewy body, vascular, and mixed dementia. In response to a specific action item in the 2012 National Plan, the National Institute of Neurological Disorders and Stroke, in collaboration with the National Institute on Aging, convened panels of experts and conducted a 2-day public conference to develop research priorities and timelines for addressing Alzheimer disease-related dementias (ADRD) in 5 topic areas: multiple etiology dementias, health disparities, Lewy body dementias including dementia with Lewy bodies and Parkinson disease dementia, frontotemporal dementia and related tauopathies, and vascular contributions to ADRD. By design, the product was up to 8 prioritized research recommendations in each topic area including estimated timelines from when work on a recommendation is started to completion or to full implementation of an ongoing activity, and recognition of shared research themes across recommendations. These included increased education and training of both researchers and health care professionals, addressing health disparities, fundamental neurobiology research, advanced diagnostics, collaborative biosample repositories, and a focus on developing effective interventions to prevent or treat ADRD by the year 2025 as targeted by the National Plan.
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Thomas J
authors: TJ
authors: Montine
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Walter J
authors: WJ
authors: Koroshetz
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Debra
authors: D
authors: Babcock
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Dennis W
authors: DW
authors: Dickson
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Wendy R
authors: WR
authors: Galpern
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: M Maria
authors: MM
authors: Glymour
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Steven M
authors: SM
authors: Greenberg
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Michael L
authors: ML
authors: Hutton
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: David S
authors: DS
authors: Knopman
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Andrey N
authors: AN
authors: Kuzmichev
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Jennifer J
authors: JJ
authors: Manly
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Karen S
authors: KS
authors: Marder
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Bruce L
authors: BL
authors: Miller
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Creighton H
authors: CH
authors: Phelps
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: William W
authors: WW
authors: Seeley
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Beth-Anne
authors: BA
authors: Sieber
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Nina B
authors: NB
authors: Silverberg
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Margaret
authors: M
authors: Sutherland
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Christine L
authors: CL
authors: Torborg
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Salina P
authors: SP
authors: Waddy
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA.
authors: Berislav V
authors: BV
authors: Zlokovic
authors: From the Department of Pathology (T.J.M.), University of Washington, Seattle; National Institute of Neurological Disorders and Stroke (W.J.K., D.B., W.R.G., A.N.K., B.-A.S., M.S., C.L.T., S.P.W., R.A.C.), Bethesda, MD; Neuropathology Lab (D.W.D.), Mayo Clinic, Jacksonville, FL; Department of Epidemiology & Biostatistics (M.M.G.), University of California San Francisco; Hemorrhagic Stroke Research Program (S.M.G.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neurodegenerative Diseases DHT at Eli Lilly and Company (M.L.H.), Lilly Research Center, Windlesham, UK; Department of Neurology (D.S.K.), Mayo Clinic Rochester, MN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M., K.S.M.), Columbia University Medical Center, New York; Columbia University (J.J.M., K.S.M.), College of Physicians and Surgeons, New York, NY; University of California San Francisco Memory and Aging Center (B.L.M., W.W.S.); National Institute on Aging (C.H.P., N.B.S.), Bethesda, MD; and Zilhka Neurogenetic Institute (B.V.Z.), Center for Neurodegeneration and Regeneration and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, CA. roderick.corriveau@nih.gov.
authors: Roderick A
authors: RA
authors: Corriveau
mesh_terms: D000544:Alzheimer Disease; D003704:Dementia; D006801:Humans; D012106:Research; D014481:United States