title: CHARGE syndrome: an overview on dental and maxillofacial features.
abstract: OBJECTIVE
  CHARGE is an acronym referring to the aspects of this rare syndromic condition. Patients with CHARGE association are today considered as subjects lacking in pathognomonic dental alterations. The present study is aimed at adding to the body of evidence of the cases reported in literature and the continuous clinical research which show a clinical picture which is strongly associated with patients afflicted by this syndrome.
  
  
  METHODS
  We report a case-series of 8 patients with CHARGE syndrome. The dental features associated with CHARGE syndrome are from case-reports, but without a congruity that can lead to a definition of the dental condition typical of the CHARGE phenotype.
  
  
  CONCLUSIONS
  The systemic problems affecting these patients are predominant in compromising their quality of life: this is the reason for a frequent lack of a diagnostics and interceptive phase, relative to oral diseases. We report new oral pathological conditions affecting CHARGE patients. Knowledge of these pathological conditions may induce dentists to carry out specific diagnoses of these patients, thus, avoiding the deterioration of oral conditions.
authors: Department of  Dental Sciences and Surgery, University of Bari, Bari, Italy. f.inchingolo@uniba.it.
authors: F
authors: F
authors: Inchingolo
authors: A
authors: A
authors: Pacifici
authors: M
authors: M
authors: Gargari
authors: J I
authors: JI
authors: Acitores Garcia
authors: M
authors: M
authors: Amantea
authors: M
authors: M
authors: Marrelli
authors: G
authors: G
authors: Dipalma
authors: A M
authors: AM
authors: Inchingolo
authors: R
authors: R
authors: Rinaldi
authors: A D
authors: AD
authors: Inchingolo
authors: L
authors: L
authors: Pacifici
authors: M
authors: M
authors: Tatullo
mesh_terms: D058747:CHARGE Syndrome / Q000473:pathology*; D002648:Child; D005260:Female; D006801:Humans; D019767:Maxillofacial Abnormalities / Q000473:pathology*; D009059:Mouth Diseases / Q000473:pathology*; D011788:Quality of Life