title: Predictive factors for a single successful cytapheresis session during the first mobilisation.
abstract: To avoid repeated apheresis, the objective of this study was to analyse the predictive factors for a single successful cytapheresis during the first mobilisation. The pre-collection characteristics of 170 lymphoma and 95 myeloma patients were analysed. Among 60 lymphoma patients who had less than 30 CD34 cells/mm(3) the day before the first apheresis, an increase in the CD34 cell count between Day -1 and Day 1 was predictive of first stem cell mobilisation success, with a sensitivity of 100% if the Day 1 was higher than 30/mm(3) (10/60 patients). Success rate of obtaining an appropriate number of stem cells in one apheresis was 120 among 170 patients.
authors: Service d'Hématologie Clinique, Centre Hospitalier Universitaire, Caen, France; Université Caen, France. Electronic address: gac-ac@chu-caen.fr.
authors: A C
authors: AC
authors: Gac
authors: Université Caen, France; Etablissement Français du Sang, Caen, France; Centre de Lutte contre le Cancer François Baclesse, Caen, France; Unité de Biostatistiques, Centre Hospitalier Universitaire, Caen, France.
authors: J J
authors: JJ
authors: Parienti
authors: Service d'Hématologie Clinique, Centre Hospitalier Universitaire, Caen, France.
authors: S
authors: S
authors: Chantepie
authors: Service d'Hématologie Clinique, Centre Hospitalier Universitaire, Caen, France.
authors: S
authors: S
authors: Cheze
authors: Service d'Hématologie Clinique, Centre Hospitalier Universitaire, Caen, France.
authors: H
authors: H
authors: Johnson-Ansah
authors: Service d'Hématologie Clinique, Centre Hospitalier Universitaire, Caen, France.
authors: K
authors: K
authors: Benabed
authors: Service d'Hématologie Clinique, Centre Hospitalier Universitaire, Caen, France.
authors: M
authors: M
authors: Macro
authors: Etablissement Français du Sang, Caen, France.
authors: V
authors: V
authors: Lefevre
authors: Etablissement Français du Sang, Caen, France.
authors: A
authors: A
authors: Batho
authors: Centre de Lutte contre le Cancer François Baclesse, Caen, France.
authors: C
authors: C
authors: Fruchart
authors: Service d'Hématologie Clinique, Centre Hospitalier Universitaire, Caen, France.
authors: O
authors: O
authors: Reman
mesh_terms: D000328:Adult; D000368:Aged; D018952:Antigens, CD34 / Q000097:blood; D015331:Cohort Studies; D016238:Cytapheresis / Q000379:methods*; D005260:Female; D019650:Hematopoietic Stem Cell Mobilization / Q000379:methods*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008223:Lymphoma / Q000097:blood / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000097:blood / Q000175:diagnosis* / Q000628:therapy*; D011237:Predictive Value of Tests; D011379:Prognosis; D019172:Transplantation Conditioning / Q000379:methods; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D018952:Antigens, CD34
keywords: Lymphoma; Multiple myeloma; Plerixafor; Single apheresis; Stem cell mobilisation