title: Testosterone deficiency and quality of life in Australasian testicular cancer survivors: a prospective cohort study.
abstract: This is the first prospective study in a contemporary Australian/New Zealand population to determine the prevalence of testosterone deficiency in testicular cancer survivors at 12 months from treatment, and any association with poorer quality of life. Hormone assays from 54 evaluable patients in a prospective cohort study revealed biochemical hypogonadism in 18 patients (33%) and low-normal testosterone in 13 patients (24%). We found no association between testosterone levels and quality of life (all P > 0.05). Hypogonadal patients should be considered for testosterone replacement to prevent long-term morbidity.
authors: Chris O'Brien Lifehouse, Sydney, New South Wales, Australia; Sydney Medical School, Sydney, New South Wales, Australia.
authors: B
authors: B
authors: O'Carrigan
authors: M
authors: M
authors: Fournier
authors: I N
authors: IN
authors: Olver
authors: M R
authors: MR
authors: Stockler
authors: H
authors: H
authors: Whitford
authors: G C
authors: GC
authors: Toner
authors: D B
authors: DB
authors: Thomson
authors: I D
authors: ID
authors: Davis
authors: F
authors: F
authors: Hanning
authors: N
authors: N
authors: Singhal
authors: C
authors: C
authors: Underhill
authors: P
authors: P
authors: Clingan
authors: A
authors: A
authors: McDonald
authors: A
authors: A
authors: Boland
authors: P
authors: P
authors: Grimison
mesh_terms: D000328:Adult; D001315:Australia / Q000453:epidemiology; D005500:Follow-Up Studies; D020249:Hormone Replacement Therapy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009373:Neoplasms, Germ Cell and Embryonal / Q000097:blood* / Q000188:drug therapy / Q000453:epidemiology; D009520:New Zealand / Q000453:epidemiology; D015995:Prevalence; D011446:Prospective Studies; D011788:Quality of Life; D015996:Survival Rate / Q000639:trends; D017741:Survivors; D013736:Testicular Neoplasms / Q000097:blood* / Q000188:drug therapy / Q000453:epidemiology; D013739:Testosterone / Q000172:deficiency*; D055815:Young Adult
chemical_list: D013739:Testosterone
keywords: hypogonadism; quality of life; testicular cancer