title: Differentially private distributed logistic regression using private and public data.
abstract: BACKGROUND
  Privacy protecting is an important issue in medical informatics and differential privacy is a state-of-the-art framework for data privacy research. Differential privacy offers provable privacy against attackers who have auxiliary information, and can be applied to data mining models (for example, logistic regression). However, differentially private methods sometimes introduce too much noise and make outputs less useful. Given available public data in medical research (e.g. from patients who sign open-consent agreements), we can design algorithms that use both public and private data sets to decrease the amount of noise that is introduced.
  
  
  METHODS
  In this paper, we modify the update step in Newton-Raphson method to propose a differentially private distributed logistic regression model based on both public and private data.
  
  
  RESULTS
  We try our algorithm on three different data sets, and show its advantage over: (1) a logistic regression model based solely on public data, and (2) a differentially private distributed logistic regression model based on private data under various scenarios.
  
  
  CONCLUSIONS
  Logistic regression models built with our new algorithm based on both private and public datasets demonstrate better utility than models that trained on private or public datasets alone without sacrificing the rigorous privacy guarantee.
authors: Zhanglong
authors: Z
authors: Ji
authors: Xiaoqian
authors: X
authors: Jiang
authors: Shuang
authors: S
authors: Wang
authors: Li
authors: L
authors: Xiong
authors: Lucila
authors: L
authors: Ohno-Machado
mesh_terms: D022126:Access to Information; D000465:Algorithms; D001943:Breast Neoplasms / Q000453:epidemiology / Q000378:metabolism / Q000473:pathology; D057225:Data Mining / Q000379:methods*; D006801:Humans; D016015:Logistic Models; D008490:Medical Informatics / Q000379:methods*; D010351:Patient Discharge / Q000706:statistics & numerical data; D018907:Privacy