title: Skin sensitivity and intolerance in Shanghai: cumulative influence of different meteorological parameters.
abstract: BACKGROUND
  Although Sensitive skin (SS) conditions are reported to be affected by climate changes, the correlations with meteorological parameters remain mostly unclear.
  
  
  OBJECTIVE
  To investigate the changes of facial skin conditions in different seasons in Shanghai, including the speed and severity of the influences imposed by different meteorological parameters.
  
  
  METHODS
  Totally eighty-one healthy female volunteers completed the study in both spring (May) and summer (August). Evaluations of facial skin conditions included stimulating sensory test, clinical grading and biophysical measurements. Correlations between the meteorological parameters and ΔTEWL as well as clinical parameters were analyzed.
  
  
  RESULTS
  There was no significant difference between two seasons in lactic acid sting test. The stimulation sensations felt by Vitamin B3 (VB3) containing cream was significantly higher in May than that in August. In accordance, baseline visual scores for erythema and scaliness in May were also significantly higher than those scores in August. The baseline transepidermal water loss (TEWL) value was significantly higher in May than that in August. Positive correlations were detected between ΔTEWL and atmospheric pressure on the test day, adjust 3-day and 7-day mean of daily solar radiation respectively. There were negative correlations between ΔTEWL and temperature outside on the test day, adjust 3-day mean as well as adjust 7-day mean of relative humidity.
  
  
  CONCLUSIONS
  Facial skin conditions in summer are better than that in spring in Shanghai. The influences from atmospheric pressure and temperature are relatively quick in speed, while the influences from relative humidity and solar radiation are slow but cumulative.
authors: Department of Skin & Cosmetic Research, Shanghai Skin Disease Hospital , Shanghai , P.R. China .
authors: Yi M
authors: YM
authors: Tan
authors: Xue M
authors: XM
authors: Wang
authors: Chao
authors: C
authors: Yuan
authors: Ya W
authors: YW
authors: Tang
authors: Sheng J
authors: SJ
authors: Luo
authors: Jie
authors: J
authors: Mao
authors: Subramanyan
authors: S
authors: Kumar
authors: Sona
authors: S
authors: Pushker
authors: Jian F
authors: JF
authors: Du
authors: Zhi K
authors: ZK
authors: Yuan
mesh_terms: D000293:Adolescent; D000328:Adult; D002681:China; D057231:Climate Change; D005145:Face; D005260:Female; D006801:Humans; D012871:Skin Diseases / Q000209:etiology*; D055815:Young Adult
keywords: Cumulative influence; meteorological parameter; skin barrier; skin surface temperature; stimulating sensory