title: A rare association of celiac disease and aplastic anemia: case report of a child and review of literature.
abstract: An association between severe aplastic anemia and other autoimmune diseases is rare and has been described in adults for eosinophilic fasciitis, thymomas, systemic lupus erythematosus, and thyroid disorders. Herein we report a patient with celiac disease who was not strictly following a gluten-free diet and presented with progressive pallor, fever, and weakness of 1 month's duration. On investigation, he had pancytopenia, which on subsequent evaluation revealed aplastic anemia. An association between aplastic anemia and celiac disease has rarely been reported. To the best of author's knowledge, only 1 pediatric case of celiac disease associated with aplastic anemia has been published. This is the second report to suggest such an association in children.
authors: 1 Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors: Rama Kumari
authors: RK
authors: Badyal
authors: Man Updesh Singh
authors: MU
authors: Sachdeva
authors: Neelam
authors: N
authors: Varma
authors: Babu Ram
authors: BR
authors: Thapa
mesh_terms: D000741:Anemia, Aplastic / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000628:therapy; D000961:Antilymphocyte Serum / Q000627:therapeutic use; D001803:Blood Transfusion; D001856:Bone Marrow Examination; D002446:Celiac Disease / Q000150:complications* / Q000175:diagnosis / Q000178:diet therapy / Q000276:immunology; D002648:Child; D055050:Diet, Gluten-Free; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D055118:Medication Adherence; D013256:Steroids / Q000627:therapeutic use; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000961:Antilymphocyte Serum; D013256:Steroids
keywords: aplastic anemia; celiac disease; child; gluten-free diet