title: Anemia management among hemodyalisis patients at the University Hospital in Puerto Rico.
abstract: End-stage renal disease is frequently complicated with anemia. Iron deficiency anemia occurs in most hemodialysis patients secondary to increased iron demand driven by the accelerated erythropoiesis that occurs when stimulating agents are administered as treatment of the anemia. The purpose of this study was to determine the prevalence of anemia and iron stores in patients undergoing hemodialysis at our unit; identify their treatment and effectiveness. Medical records of fifty-three patients undergoing ambulatory hemodialysis were evaluated for three months. Patient's hemoglobin, ferritin, iron, total iron binding capacity and percent transferrin saturation were recorded. 91% patients had arterial hypertension and 62% were diabetic. The prevalence of anemia was 34%, 57% and 47% during the three-month period respectively. Only 21% of the population had transferrin saturation less than 20% and none had ferritin below 200 ng/ml. Throughout the study, the majority of patients were managed with combination of iron and erythropoietin stimulating agents (ESAs). The prevalence of anemia remained elevated despite treatment with iron and ESAs. However, 56% of anemic patients throughout the three months showed an increase in hemoglobin levels by the end of the observation period. 53% of patients were treated with iron alone or with ESAs for the three consecutive month periods and only two had transferrin saturation less than 20%. In our population, ESAs low responsiveness is not related to iron deficiency but to the morbidity of their disease.
authors: Heana E
authors: HE
authors: Ocasio
authors: Hector
authors: H
authors: Diaz
authors: José L
authors: JL
authors: Cangiano
authors: Rafael
authors: R
authors: Báez
authors: Erick
authors: E
authors: Suárez
mesh_terms: D000740:Anemia / Q000188:drug therapy* / Q000209:etiology*; D005260:Female; D006397:Hematinics / Q000627:therapeutic use*; D006785:Hospitals, University; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011647:Puerto Rico; D006435:Renal Dialysis; D012189:Retrospective Studies
chemical_list: D006397:Hematinics