title: [Molecular-genetic characterization of the Okhotskiy virus (OKHV) and Aniva virus (ANIV) (Orbivirus, Reoviridae) isolated from the ticks Ixodes (Ceratixodes) uriae White, 1852 in high latitudes of the Northern Eurasia].
abstract: Molecular-genetic characteristics of the Okhotskiy virus (OKHV) and Aniva virus (ANIV) were studied (ID GenBank KF981623-32). These viruses are distributed over the shelf and Island areas in the high latitudes in the Okhotsk, Bering, and Barents seas and linked with nesting colonies of Alcidae seabirds and their obligatory parasites, the Ixodes uriae (Ixodidae) ticks. OKHV and ANIV are observed to be independent species within the limits of the Great Island virus (GIV) group of the Orbivirus genus of the Reoviridae family. The majority of the genes of OKHV and ANIV have high homology (VP1 - 96%, T2 - 99%, VP7 (T13) - 98%, NS1 - 94%, NS2 - 98%, NS3 - 72%, VP6 - 93%). Nevertheless, the envelope proteins containing the main specific antigenic determinants (VP2 and VP5) of OKHV and ANIV are sufficiently different (62% and 68% homology for amino acid sequences, respectively).
authors: D K
authors: DK
authors: L'vov
authors: S V
authors: SV
authors: Al'khovskiĭ
authors: M Iu
authors: MIu
authors: Shchelkanov
authors: A M
authors: AM
authors: Shchetinin
authors: P G
authors: PG
authors: Deriabin
authors: A K
authors: AK
authors: Gitel'man
authors: E I
authors: EI
authors: Samokhvalov
authors: A G
authors: AG
authors: Botikov
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D046091:Charadriiformes / Q000235:genetics / Q000821:virology*; D018884:Ixodes / Q000235:genetics / Q000821:virology*; D018163:Orbivirus / Q000235:genetics* / Q000472:pathogenicity; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics
chemical_list: D012367:RNA, Viral