title: [Myo-inositol in the treatment of polycystic ovary syndrome].
abstract: OBJECTIVE
  Presentation of a comprehensive body of knowledge on the role of insulin sensitizer myo-inositol in the treatment of polycystic ovary syndrome (PCOS).
  
  
  METHODS
  Review article.
  
  
  METHODS
  Institute for the Care of Mother and Child, Prague.
  
  
  METHODS
  An overview of publishing data.
  
  
  CONCLUSIONS
  Polycystic ovary syndrome is the most common cause of ovarian dysfunction and anovulatory infertility in women. The insulin resistance occurs very frequently as a part of PCOS. This paper reviews the literature documenting the effectiveness of insulin sensitizer myo-inositol in the treatment of ovarian dysfunction, symptoms of hyperandrogenism and wide complex of symptoms of metabolic syndrome. Six randomized controlled trials provides evidence of a positive effect of myo-inositol to normalize ovarian function, improve laboratory and clinical manifestations of hyperandrogenism and insulin resistance. The myo-inositol treatment has been demonstrated as a safe method of PCOS management.
authors: P
authors: P
authors: Křepelka
mesh_terms: D005260:Female; D006801:Humans; D007294:Inositol / Q000627:therapeutic use*; D011085:Polycystic Ovary Syndrome / Q000188:drug therapy*; D014803:Vitamin B Complex / Q000627:therapeutic use
chemical_list: D014803:Vitamin B Complex; D007294:Inositol