title: [Role of hormonal regulation and stress in the interaction of sleep and biorhythms in aging].
abstract: The present work describes bibliographic analysis of ontogenetic changes in hormonal regulation of sleep and circadian biorhythms. It is suggested that two-stage, age-related dynamics of such changes may be related to differential occurrence registered by us earlier, of maxima of morbidity and mortality caused by a number of disorders, in middle-age and in senile period. It is proposed to concentrate future efforts on elaboration of mathematical models of ontogenetic regulation, on the basis of systems biomedicine.
authors: V I
authors: VI
authors: Goudochnikov
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology*; D002940:Circadian Rhythm / Q000502:physiology*; D005790:General Adaptation Syndrome / Q000453:epidemiology / Q000378:metabolism / Q000517:prevention & control; D006728:Hormones / Q000378:metabolism*; D006801:Humans; D008875:Middle Aged; D008962:Models, Theoretical; D009017:Morbidity; D012890:Sleep / Q000502:physiology*; D020178:Sleep Disorders, Circadian Rhythm / Q000453:epidemiology / Q000209:etiology / Q000378:metabolism; D013312:Stress, Physiological
chemical_list: D006728:Hormones