title: Soft tissue sarcomas.
abstract: Sarcoma is a cancer that arises from cells of mesenchymal origin, such as bone, cartilage, muscle, fat, vascular, or hematopoietic tissue. It is a very rare form of cancer with over 50 histologic subtypes. This chapter discusses selected individual subtypes of sarcomas and characteristics specific to each one. It will broadly go over molecular biology, etiology, risk factors, and the clinical features of this disease. It discusses diagnostic evaluation and the principles of management including imaging, biopsy, staging, treatment, follow-up, and the importance of a multidisciplinary approach.
authors: University of Florida, Department of Orthopaedic Surgery, Division of Oncology, UF Orthopaedics and Sports Medicine Institute, PO Box 112727, Gainesville, FL, 32611-2727, USA, spiguar@ortho.ufl.edu.
authors: Andre
authors: A
authors: Spiguel
mesh_terms: D001706:Biopsy; D005350:Fibroma / Q000175:diagnosis / Q000628:therapy; D005354:Fibrosarcoma / Q000175:diagnosis / Q000628:therapy; D006394:Hemangiosarcoma / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D007890:Leiomyosarcoma / Q000175:diagnosis / Q000628:therapy; D008080:Liposarcoma / Q000175:diagnosis / Q000628:therapy; D018317:Nerve Sheath Neoplasms / Q000175:diagnosis / Q000628:therapy; D012208:Rhabdomyosarcoma / Q000175:diagnosis / Q000628:therapy; D012307:Risk Factors; D012509:Sarcoma / Q000175:diagnosis* / Q000628:therapy*; D018227:Sarcoma, Clear Cell / Q000175:diagnosis / Q000628:therapy; D013584:Sarcoma, Synovial / Q000175:diagnosis / Q000628:therapy; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000628:therapy*