title: Dopaminergic modulation of striatal networks in health and Parkinson's disease.
abstract: In the last couple of years, there have been significant advances in our understanding of how dopamine modulates striatal circuits underlying goal-directed behaviors and how therapeutic interventions intended to normalize disordered dopaminergic signaling can go awry. This review summarizes some of the advances in this field with a translational focus on Parkinson's disease.
authors: Department of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Electronic address: j-surmeier@northwestern.edu.
authors: D James
authors: DJ
authors: Surmeier
authors: Department of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
authors: Steven M
authors: SM
authors: Graves
authors: Department of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
authors: Weixing
authors: W
authors: Shen
mesh_terms: D003342:Corpus Striatum / Q000378:metabolism / Q000473:pathology*; D004298:Dopamine / Q000378:metabolism*; D006801:Humans; D009415:Nerve Net / Q000378:metabolism*; D010300:Parkinson Disease / Q000473:pathology*; D015398:Signal Transduction / Q000502:physiology
chemical_list: D004298:Dopamine