title: Acute Eosinophilic Myocarditis and Hyper IgE in HIV Infection: A Case Report.
abstract: BACKGROUND
  Eosinophilic myocarditis is a rare cause of myocarditis. It is manifested histopathologically by diffuse or focal myocardial inflammation with eosinophilic infiltration, often in association with peripheral blood eosinophilia. Patients infected with Human Immunodeficiency Virus (HIV), especially those with lower CD4 counts, can occasionally have hyperimmunoglobulinemia E (Hyper IgE) and eosinophilia.
  
  
  METHODS
  We report a case of a 29-year-old patient with Acquired Immunodeficiency Syndrome (AIDS) who had a persistent elevation of eosinophil counts and elevated IgE levels for a year prior to admission. He was presented to our emergency department with chest pain and laboratory tests revealed peripheral blood eosinophilia and elevated troponins. Coronary angiogram showed nonobstructive coronary artery disease. He then underwent cardiac magnetic resonance imaging which was consistent with an infiltrative myocarditis. After being put on steroid therapy, his peripheral eosinophilia resolved and his cardiac symptoms improved.
  
  
  CONCLUSIONS
  Our case highlights that eosinophilia and Hyper IgE in HIV patients has the potential to contribute to end-organ damage.
authors: Department of Cardiology in Seton Hall University School of Health and Medical Sciences, South Orange,New Jersey, USA.
authors: Mohammad
authors: M
authors: Thawabi
authors: Department of Cardiology in Seton Hall University School of Health and Medical Sciences, South Orange,New Jersey, USA.
authors: Mirette
authors: M
authors: Habib
authors: Department of Internal Medicine, Saint Michael's Medical Center, Newark, New Jersey, USA.
authors: Hamid
authors: H
authors: Shaaban
authors: Department of Cardiology in Seton Hall University School of Health and Medical Sciences, South Orange,New Jersey, USA.
authors: Fayez
authors: F
authors: Shamoon
keywords: Acute eosinophilic myocarditis; HIV infection; Hyper Ig-E