title: Vitamin D status in patients admitted in a clinic of endocrinology.
abstract: Vitamin D deficiency has been known as a global health problem and there were reported moderate to strong inverse associations between 25(OH) D concentrations and cardiovascular diseases, serum lipid concentrations, inflammation, glucose metabolism disorders, weight gain, infectious diseases, multiple sclerosis, mood disorders, declining cognitive function, impaired physical functioning, and all-cause mortality. In Romania there are only a few published reports on vitamin D status among adult population.
  
  
  OBJECTIVE
  To evaluate vitamin D status in 440 patients those were admitted in our clinic for various endocrine pathology.
  
  
  METHODS
  Serum 25-hydroxy vitamin D was measured using chemiluminescence assay. We categorized the vitamin D levels in 3 subgroups (deficiency, insufficiency and sufficiency).
  
  
  RESULTS
  In our study there was a high prevalence of both vitamin D deficiency and insufficiency, while optimal level was observed only in a very small number of patients.
  
  
  CONCLUSIONS
  We demonstrated a high frequency of vitamin D deficiency in general population, especially in elderly and children. There are still many controversies regarding the optimal vitamin D status and the supplementation dosage, so long-term large scale studies are needed regarding efficacy and safety.
authors: Corina
authors: C
authors: Găleanu
authors: A
authors: A
authors: Florescu
authors: Maria Christina
authors: MC
authors: Ungureanu
authors: Ilinka
authors: I
authors: Grozavu
authors: Andra
authors: A
authors: Loghin
authors: Didona
authors: D
authors: Ungureanu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D050071:Bone Density Conservation Agents / Q000097:blood*; D002112:Calcifediol / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D004704:Endocrinology; D005260:Female; D006801:Humans; D007297:Inpatients / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D014808:Vitamin D Deficiency / Q000097:blood / Q000175:diagnosis* / Q000453:epidemiology* / Q000517:prevention & control
chemical_list: D015415:Biomarkers; D050071:Bone Density Conservation Agents; D002112:Calcifediol