title: Processed and unprocessed red meat consumption and hypertension in women.
abstract: BACKGROUND
  High processed red meat consumption is associated with increased risk of cardiovascular disease. The high sodium content of processed red meat could increase blood pressure and explain the association with cardiovascular disease.
  
  
  OBJECTIVE
  We evaluated the relation between the consumption of unprocessed and processed red meat and incident hypertension.
  
  
  METHODS
  In a prospective cohort of 44,616 disease-free French women who responded to a validated dietary questionnaire, we observed 10,256 incident cases of hypertension between 1993 and 2008. Cases were identified through self-reports of diagnosed or treated hypertension. Multivariate Cox regression models were adjusted for age, education, smoking, physical activity, body mass index, menopause, menopausal hormone therapy, and alcohol, bread, coffee, and fruit and vegetable consumption.
  
  
  RESULTS
  Women who consumed ≥5 servings of processed red meat/wk (50 g = 1 serving) had a 17% higher rate of hypertension than that of women who consumed <1 serving/wk (HR: 1.17; 95% CI: 1.09, 1.26; P-trend = 0.0002). No association was observed between unprocessed red meat consumption and hypertension. When women who consumed ≥5 servings of unprocessed red meat/wk (100 g = 1 serving) were compared with women who consumed <1 serving unprocessed red meat/wk, the multivariate HR was 0.99 (95% CI: 0.91, 1.08; P-trend = 0.63).
  
  
  CONCLUSIONS
  In this large prospective cohort of French women, we observed an association between the consumption of processed red meat and hypertension. We observed no association for unprocessed red meat consumption and hypertension.
authors: From the Center for Research on Population Health, Instituto Nacional de Salud Pública, Cuernavaca, México (ML); the Department of Epidemiology, Harvard School of Public Health, Boston, MA (ML); the Institut National de la Santé et de la Recherche Médicale, Center for Research in Epidemiology and Population Health, Unit 1018, Villejuif, France (ML, AB, GF, ER, M-CB-R, and FC-C); and the Paris-South University, Unité Mixte de Recherche et de Service 1018, Villejuif, France (AB, GF, ER, M-CB-R, and FC-C).
authors: Martin
authors: M
authors: Lajous
authors: From the Center for Research on Population Health, Instituto Nacional de Salud Pública, Cuernavaca, México (ML); the Department of Epidemiology, Harvard School of Public Health, Boston, MA (ML); the Institut National de la Santé et de la Recherche Médicale, Center for Research in Epidemiology and Population Health, Unit 1018, Villejuif, France (ML, AB, GF, ER, M-CB-R, and FC-C); and the Paris-South University, Unité Mixte de Recherche et de Service 1018, Villejuif, France (AB, GF, ER, M-CB-R, and FC-C).
authors: Anne
authors: A
authors: Bijon
authors: From the Center for Research on Population Health, Instituto Nacional de Salud Pública, Cuernavaca, México (ML); the Department of Epidemiology, Harvard School of Public Health, Boston, MA (ML); the Institut National de la Santé et de la Recherche Médicale, Center for Research in Epidemiology and Population Health, Unit 1018, Villejuif, France (ML, AB, GF, ER, M-CB-R, and FC-C); and the Paris-South University, Unité Mixte de Recherche et de Service 1018, Villejuif, France (AB, GF, ER, M-CB-R, and FC-C).
authors: Guy
authors: G
authors: Fagherazzi
authors: From the Center for Research on Population Health, Instituto Nacional de Salud Pública, Cuernavaca, México (ML); the Department of Epidemiology, Harvard School of Public Health, Boston, MA (ML); the Institut National de la Santé et de la Recherche Médicale, Center for Research in Epidemiology and Population Health, Unit 1018, Villejuif, France (ML, AB, GF, ER, M-CB-R, and FC-C); and the Paris-South University, Unité Mixte de Recherche et de Service 1018, Villejuif, France (AB, GF, ER, M-CB-R, and FC-C).
authors: Emilie
authors: E
authors: Rossignol
authors: From the Center for Research on Population Health, Instituto Nacional de Salud Pública, Cuernavaca, México (ML); the Department of Epidemiology, Harvard School of Public Health, Boston, MA (ML); the Institut National de la Santé et de la Recherche Médicale, Center for Research in Epidemiology and Population Health, Unit 1018, Villejuif, France (ML, AB, GF, ER, M-CB-R, and FC-C); and the Paris-South University, Unité Mixte de Recherche et de Service 1018, Villejuif, France (AB, GF, ER, M-CB-R, and FC-C).
authors: Marie-Christine
authors: MC
authors: Boutron-Ruault
authors: From the Center for Research on Population Health, Instituto Nacional de Salud Pública, Cuernavaca, México (ML); the Department of Epidemiology, Harvard School of Public Health, Boston, MA (ML); the Institut National de la Santé et de la Recherche Médicale, Center for Research in Epidemiology and Population Health, Unit 1018, Villejuif, France (ML, AB, GF, ER, M-CB-R, and FC-C); and the Paris-South University, Unité Mixte de Recherche et de Service 1018, Villejuif, France (AB, GF, ER, M-CB-R, and FC-C).
authors: Françoise
authors: F
authors: Clavel-Chapelon
mesh_terms: D000818:Animals; D002417:Cattle; D015331:Cohort Studies; D002149:Energy Intake; D005260:Female; D005500:Follow-Up Studies; D005602:France / Q000453:epidemiology; D006736:Horses; D006801:Humans; D006973:Hypertension / Q000453:epidemiology / Q000209:etiology*; D015994:Incidence; D059012:Lost to Follow-Up; D008460:Meat / Q000009:adverse effects*; D008461:Meat Products / Q000009:adverse effects*; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D057566:Self Report; D034561:Sheep, Domestic; D034421:Sus scrofa