title: Ductal adenocarcinoma of the prostate: a Hong Kong case series.
abstract: OBJECTIVE
  To review and report our local experience in the management of ductal adenocarcinoma of the prostate.
  
  
  METHODS
  Retrospective review of patients diagnosed with ductal adenocarcinoma of the prostate in two regional urological centres in Hong Kong during 1995-2009. Clinical information, treatment and outcomes were retrieved for further analysis.
  
  
  RESULTS
  We identified 19 Chinese patients diagnosed with ductal adenocarcinoma of the prostate. Majority of our patients presented with retention of urine and haematuria. At presentation, seven patients were already at an advanced stage with evidence of rectal invasion or distant metastasis. The overall treatment outcome was poor with high failure rate after either local or systemic hormonal therapy.
  
  
  CONCLUSIONS
  We observed a predilection of this tumour to be locally aggressive, and hence a relatively high incidence of intra-luminal growth and rectal invasion. We observed a high failure rate after either radical prostatectomy or hormonal therapy.
authors: Division of Urology, Queen Elizabeth Hospital, Kowloon, Hong Kong, kwm.raymond@yahoo.com.
authors: Raymond Wai Man
authors: RW
authors: Kan
authors: Chi Fai
authors: CF
authors: Kan
authors: Joseph Hon Ming
authors: JH
authors: Wong
authors: Kenneth Kam Fung
authors: KK
authors: Fu
authors: Chi Fai
authors: CF
authors: Ng
authors: Steve Wai Hee
authors: SW
authors: Chan
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D044584:Carcinoma, Ductal / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D003131:Combined Modality Therapy; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration; D005500:Follow-Up Studies; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D012007:Rectum; D012189:Retrospective Studies