title: Highly enantioselective hydrogenation of steric hindrance enones catalyzed by Ru complexes with chiral diamine and achiral phosphane.
abstract: An asymmetric hydrogenation of sterically hindered β,β-disubstituted enones has been well-established by using a ruthenium complex composed of an achiral diphosphane and a chiral diamine as catalyst, wherein the carbonyl group was selectively hydrogenated to give a wide range of chiral allylic alcohols with high levels of enantioselectivity and complete chemoselectivity.
authors: State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences , Lanzhou 730000, China.
authors: Xiangning
authors: X
authors: Chen
authors: Han
authors: H
authors: Zhou
authors: Kunyu
authors: K
authors: Zhang
authors: Jiawen
authors: J
authors: Li
authors: Hanmin
authors: H
authors: Huang
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003959:Diamines / Q000737:chemistry*; D006865:Hydrogenation; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D010720:Phosphines / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000438:Alcohols; D003959:Diamines; D007659:Ketones; D010720:Phosphines; D012428:Ruthenium; C044646:phosphine