title: Tumor models: tumor-stroma interactions drive neoplastic transformation in Drosophila.
abstract: Stromal cells play a supportive role in the initiation and progression of carcinomas. A new study in Drosophila implicates mesenchymal cells in supporting EGF receptor-driven tumor growth and cellular transformation of epithelial tissues.
authors: ICREA and Institute for Research in Biomedicine, Parc Cientific de Barcelona, Baldiri Reixac, 10-12, 08028 Barcelona, Spain. Electronic address: marco.milan@irbbarcelona.org.
authors: Marco
authors: M
authors: Milán
mesh_terms: D000818:Animals; D063646:Carcinogenesis / Q000235:genetics*; D002471:Cell Transformation, Neoplastic / Q000378:metabolism*; D004848:Epithelium / Q000378:metabolism*; D060227:Imaginal Discs / Q000254:growth & development*; D008648:Mesoderm / Q000378:metabolism*; D008954:Models, Biological