title: Solvent selection in ultrasonic-assisted emulsification microextraction: Comparison between high- and low-density solvents by means of novel type of extraction vessel.
abstract: There are numerous published reports about dispersive liquid phase microextraction of the wide range of substances, however, till now no broadly accepted systematic and purpose oriented selection of extraction solvent has been proposed. Most works deal with the optimization of available solvents without adequate pre-consideration of properness. In this study, it is tried to compare the performances of low- and high-density solvents at the same conditions by means of novel type of extraction vessel with head and bottom conical shape. Extraction efficiencies of seven basic pharmaceutical compounds using eighteen common organic solvents were studied in this work. It was much easier to work with high-density solvents and they mostly showed better performances. This work shows that although exact predicting the performance of the solvents is multifaceted case but the pre-consideration of initial selection of solvents with attention to the physiochemical properties of the desired analytes is feasible and promising. Finally, the practicality of the method for extraction from urine and plasma samples was investigated.
authors: Faculty of Chemistry, Shahid Beheshti University, G. C., 1983963113, Evin, Tehran, Iran. Electronic address: s_nojavan@sbu.ac.ir.
authors: Saeed
authors: S
authors: Nojavan
authors: Faculty of Chemistry, Shahid Beheshti University, G. C., 1983963113, Evin, Tehran, Iran.
authors: Tayebeh
authors: T
authors: Gorji
authors: Faculty of Chemistry, Shahid Beheshti University, G. C., 1983963113, Evin, Tehran, Iran.
authors: Saied Saeed Hosseiny
authors: SS
authors: Davarani
authors: Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2, Canada. Electronic address: mortezan@ualberta.ca.
authors: Amin
authors: A
authors: Morteza-Najarian
keywords: Dispersive liquid phase microextraction; Extraction vessel; Plasma analysis; Ultrasonic assisted emulsification microextraction; Urine analysis