title: The pharmacologic treatment of short bowel syndrome: new tricks and novel agents.
abstract: Short bowel syndrome (SBS) is a manifestation of massive resection of the intestines resulting in severe fluid, electrolyte, and vitamin/mineral deficiencies. Diet and parenteral nutrition play a large role in the management of SBS; however, pharmacologic options are becoming more readily available. These pharmacologic agents focus on reducing secretions and stimulating intestinal adaptation. The choice of medication is highly dependent on the patient's symptoms, remaining anatomy, and risk versus benefit profile for each agent. This article focuses on common and novel pharmacologic medications used in SBS, including expert advice on their indications and use.
authors: Departments of Medicine, University of Missouri, Columbia, MO, USA.
authors: Matthew L
authors: ML
authors: Bechtold
authors: Stephen A
authors: SA
authors: McClave
authors: Lena B
authors: LB
authors: Palmer
authors: Douglas L
authors: DL
authors: Nguyen
authors: Lindsay M
authors: LM
authors: Urben
authors: Robert G
authors: RG
authors: Martindale
authors: Ryan T
authors: RT
authors: Hurt
mesh_terms: D000930:Antidiarrheals / Q000627:therapeutic use; D006133:Growth Substances / Q000627:therapeutic use; D006801:Humans; D054328:Proton Pump Inhibitors / Q000627:therapeutic use; D012778:Short Bowel Syndrome / Q000178:diet therapy / Q000188:drug therapy* / Q000453:epidemiology / Q000503:physiopathology
chemical_list: D000930:Antidiarrheals; D006133:Growth Substances; D054328:Proton Pump Inhibitors