title: Cupriavidus pauculus bacteremia in a child on extracorporeal membrane oxygenation.
abstract: We report a case of bacteremia secondary to Cupriavidus pauculus in a 15-month-old boy on extracorporeal membrane oxygenation (ECMO). The source of the organism was water in the thermoregulator reservoir. The child responded well to cefepime and ciprofloxacin, a delayed oxygenator change out and replacement of the thermoregulator reservoir with a unit that was cleaned and decontaminated with sodium hypochlorite. Isolation of Cupriavidus pauculus from a patient on ECMO support should raise suspicion of the reservoir as a source.
authors: From the *Division of Pediatric Infectious Diseases; †Department of Anesthesiology; and ‡Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota.
authors: Adaora S
authors: AS
authors: Uzodi
authors: Gregory J
authors: GJ
authors: Schears
authors: James R
authors: JR
authors: Neal
authors: Nancy K
authors: NK
authors: Henry
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D016470:Bacteremia / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D000077723:Cefepime; D002511:Cephalosporins / Q000008:administration & dosage; D002939:Ciprofloxacin / Q000008:administration & dosage; D049921:Cupriavidus / Q000302:isolation & purification; D003666:Decontamination; D004197:Disease Reservoirs / Q000382:microbiology; D004359:Drug Therapy, Combination; D015199:Extracorporeal Membrane Oxygenation / Q000009:adverse effects* / Q000295:instrumentation; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D016027:Heart Transplantation; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome / Q000150:complications / Q000628:therapy; D007223:Infant; D008297:Male; D014871:Water Microbiology
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D002939:Ciprofloxacin; D000077723:Cefepime