title: A critical role for natural killer cells in dendritic cell-based anticancer immunotherapy.
abstract: Multipronged immunotherapies that activate both T cells and natural killer (NK) cells may result in more robust and durable anticancer responses. The successful outcome of dendritic cell (DC)-based vaccination therapy involves a hitherto unrecognized role for NK cells. Combinatorial regimens that enhance the contribution of NK cells to the anticancer immune response may therefore improve clinical outcomes.
authors: Department of Microbiology and Immunology; University of Otago; Dunedin, New Zealand.
authors: Alexander D
authors: AD
authors: McLellan
keywords: cancer; dendritic cell; immunotherapy; melanoma; natural killer cell