title: [The practical application of marker -2proPSA and health index of prostate phi in diagnostics of prostate cancer].
abstract: The article demonstrates that prostate-specific antigen (PSA) has some limitations in detection of cancer of prostate. It was demonstrated that isoform of free PSA - 2proPSA has higher specificity in comparison with total PSA (tPSA) and percentage tPSA and free PSA (%free PSA) in detection of cancer of prostate. The application of Prostate Health Index including such indicators as -2PSA, free PSA and tPSA makes it possible to increase degree of detection of cancer of prostate, to increase specificity and to decrease number of optional biopsies. Besides, correlation was established between value of Prostate Health Index and degree of aggressiveness of forms of cancer of prostate.
authors: A V
authors: AV
authors: Ruzhanskaya
authors: S A
authors: SA
authors: Evgina
authors: I I
authors: II
authors: Skibo
mesh_terms: D055088:Early Detection of Cancer / Q000379:methods; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D017430:Prostate-Specific Antigen / Q000097:blood* / Q000737:chemistry; D011471:Prostatic Neoplasms / Q000097:blood*; D020033:Protein Isoforms; D012680:Sensitivity and Specificity
chemical_list: D020033:Protein Isoforms; D017430:Prostate-Specific Antigen