title: Treatment-related dysgeusia in head and neck cancer patients.
abstract: Head and neck cancer patients treated with radiotherapy and/or chemotherapy agents may develop altered taste acuity. This, together with radiation induced xerostomia and dysphagia, is a major contributory factor to the anorexia and concomitant morbidity often seen in this group of patients. This paper examines the existing literature in order to assess the prevalence of clinician and patient-reported dysgeusia in HNC patients undergoing oncological treatment. We also describe the temporal manifestations of the same and its reported impact on QOL.
authors: Head & Neck Research Unit, Royal Marsden Hospital, 3rd Floor, Mulberry House, London SW3 6JJ, UK. Electronic address: eirune@nhs.net.
authors: Ekpemi
authors: E
authors: Irune
authors: Head & Neck Research Unit, Royal Marsden Hospital, 3rd Floor, Mulberry House, London SW3 6JJ, UK. Electronic address: raghav.rmh@gmail.com.
authors: Raghav C
authors: RC
authors: Dwivedi
authors: Head & Neck Research Unit, Royal Marsden Hospital, 3rd Floor, Mulberry House, London SW3 6JJ, UK; Institute of Cancer Research, Chester Beatty Laboratories, 237 Fulham Road, London SW3 6JB, UK. Electronic address: Chris.Nutting@icr.ac.uk.
authors: Christopher M
authors: CM
authors: Nutting
authors: Head & Neck Research Unit, Royal Marsden Hospital, 3rd Floor, Mulberry House, London SW3 6JJ, UK; Institute of Cancer Research, Chester Beatty Laboratories, 237 Fulham Road, London SW3 6JB, UK. Electronic address: Kevin.Harrington@icr.ac.uk.
authors: Kevin J
authors: KJ
authors: Harrington
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects; D004307:Dose-Response Relationship, Radiation; D004408:Dysgeusia / Q000453:epidemiology / Q000209:etiology*; D006258:Head and Neck Neoplasms / Q000532:radiotherapy* / Q000628:therapy; D006801:Humans; D011788:Quality of Life; D011878:Radiotherapy / Q000009:adverse effects*; D013649:Taste; D014987:Xerostomia / Q000209:etiology
chemical_list: D000970:Antineoplastic Agents
keywords: Ageusia; Anorexia; Dysgeusia; Head and neck cancer; Oral cancer; Oropharyngeal cancer; Quality of life; Radiotherapy; Taste