title: Electrochemical device based on a Pt nanosphere-paper working electrode for in situ and real-time determination of the flux of H2O2 releasing from SK-BR-3 cancer cells.
abstract: A novel paper working electrode with Pt nanospheres grown in it (Pt-PWE) was first used as a sensor platform and then cancer cells were immobilized on the Pt-PWE (high affinity binding with aptamers). This electrode was first designed to achieve the in situ and real-time determination of H2O2 released from cancer cells to obtain an accurate determination.
authors: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, University of Jinan, Jinan 250022, P. R. China. ujn.yujh@gmail.com.
authors: Fang
authors: F
authors: Liu
authors: Shenguang
authors: S
authors: Ge
authors: Jinghua
authors: J
authors: Yu
authors: Mei
authors: M
authors: Yan
authors: Xianrang
authors: X
authors: Song
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects / Q000502:physiology; D001943:Breast Neoplasms / Q000737:chemistry* / Q000378:metabolism; D045744:Cell Line, Tumor; D055664:Electrochemical Techniques / Q000379:methods*; D004566:Electrodes; D005260:Female; D006801:Humans; D006861:Hydrogen Peroxide / Q000032:analysis* / Q000378:metabolism; D054118:Nanospheres / Q000737:chemistry*; D010209:Paper; D010984:Platinum / Q000737:chemistry*
chemical_list: D000970:Antineoplastic Agents; D010984:Platinum; D006861:Hydrogen Peroxide