title: Towards intelligent bioreactor systems: triggering the release and mixing of compounds based on DNA-functionalized hybrid hydrogel.
abstract: We have designed and synthesized an intelligent mesoporous silica nanoparticle-DNA hydrogel bioreactor system that can be controlled by external stimuli. The system allowed the simultaneous incorporation of multiple components, and the separation between the components can be destroyed by a structural change of the DNA to initiate a reaction.
authors: State Key Laboratory of Rare Earth Resource Utilization and Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China. jren@ciac.ac.cn xqu@ciac.ac.cn.
authors: Li
authors: L
authors: Zhou
authors: Cuie
authors: C
authors: Chen
authors: Jinsong
authors: J
authors: Ren
authors: Xiaogang
authors: X
authors: Qu
mesh_terms: D019149:Bioreactors; D004247:DNA / Q000138:chemical synthesis* / Q000378:metabolism; D020100:Hydrogels / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D020100:Hydrogels; D004247:DNA