title: Room-temperature palladium-catalyzed direct 2-arylation of benzoxazoles with aryl and heteroaryl bromides.
abstract: An efficient room-temperature palladium-catalyzed direct 2-arylation of benzoxazoles with aryl bromides is presented. The Pd(OAc)2/NiXantphos-based catalyst enables the introduction of various aryl and heteroaryl groups, via a deprotonative cross-coupling process (DCCP) in good to excellent yields (60-99%).
authors: Department of Medicinal Plants, Agronomy College, Sichuan Agricultural University, No. 211, Huimin Road, Wenjiang Region, Chengdu 611130, P. R. China.
authors: Feng
authors: F
authors: Gao
authors: Byeong-Seon
authors: BS
authors: Kim
authors: Patrick J
authors: PJ
authors: Walsh
mesh_terms: D001583:Benzoxazoles / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D056831:Coordination Complexes / Q000737:chemistry; D006842:Hydrocarbons, Brominated; D006859:Hydrogen / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D013696:Temperature
chemical_list: D001583:Benzoxazoles; D056831:Coordination Complexes; D006842:Hydrocarbons, Brominated; D010165:Palladium; D002244:Carbon; D006859:Hydrogen