title: Small calcified lesions suggestive of neurocysticercosis are associated with mesial temporal sclerosis.
abstract: Recent studies have suggested a possible relationship between temporal lobe epilepsy with mesial temporal sclerosis (MTS) and neurocysticercosis (NC). We performed a case-control study to evaluate the association of NC and MTS.
  
  
  METHODS
  We randomly selected patients with different epilepsy types, including: MTS, primary generalized epilepsy (PGE) and focal symptomatic epilepsy (FSE). Patients underwent a structured interview, followed by head computed tomography (CT). A neuroradiologist evaluated the scan for presence of calcified lesions suggestive of NC. CT results were matched with patients' data.
  
  
  RESULTS
  More patients in the MTS group displayed calcified lesions suggestive of NC than patients in the other groups (p=0.002). On multivariate analysis, MTS was found to be an independent predictor of one or more calcified NC lesions (p=0.033).
  
  
  CONCLUSIONS
  After controlling for confounding factors, we found an independent association between NC calcified lesions and MTS.
authors: Departamento de Neurologia, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, SP, Brazil.
authors: Marcos C B
authors: MC
authors: Oliveira
authors: Laboratório de Investigações Médicas 44, Instituto de Radiologia, Hospital das Clínicas, Faculdade de Medicina de São Paulo, Sao Paulo, SP, Brazil.
authors: Maria G M
authors: MG
authors: Martin
authors: Departamento de Bioestatística, Instituto de Biociências, Campus de Botucatu Distrito de Rubião Júnior, Universidade Estadual Paulista ?Júlio de Mesquita Filho?, Botucatu, SP, Brazil.
authors: Miriam H
authors: MH
authors: Tsunemi
authors: Instituto de Radiologia, Hospital das Clínicas, Faculdade de Medicina de São Paulo, Sao Paulo, SP, Brazil.
authors: Gilson
authors: G
authors: Vieira
authors: Departamento de Neurologia, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, SP, Brazil.
authors: Luiz H M
authors: LH
authors: Castro
mesh_terms: D000328:Adult; D002114:Calcinosis / Q000000981:diagnostic imaging*; D016022:Case-Control Studies; D004833:Epilepsy, Temporal Lobe / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D020019:Neurocysticercosis / Q000000981:diagnostic imaging*; D012598:Sclerosis; D013702:Temporal Lobe / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed