title: New sesquiterpene coumarin from the roots of Ferula latisecta.
abstract: OBJECTIVE
  The genus of Ferula belongs to the tribe Peucedaneae, subfamily of Apioideae and family of Umbelliferae with 133 species distributed throughout the Mediterranean area and central Asia, especially in the former USSR and neighboring countries such as Iran. The popular Persian name of the most of these species is "Koma". In this research we tried to isolate and elucidate the structure of new sesquiterpene in the root of Ferula latisecta (F. latisecta).
  
  
  METHODS
  Dried and powdered roots of F. latisecta were extracted with CH2Cl2 using a Soxhlet apparatus. The extract was concentrated in vacuo to give a red extract. The extract was subjected to column chromatography on silica gel. (1)H NMR, (13)C NMR, DEPT, (1)H-(1)H COSY, HMBC, HSQC, and NOESY spectra were the methods we used to elucidate the structure of new sesquiterpene in this plant.
  
  
  RESULTS
  One new sesquieterpene coumarin, namely Latisectin and IUPAC name [1-(2-Hydroxy-4-methoxy-phenyl)-3,4,8,12-tetramethyl-trideca-4,7,11-trien-1-one ] , together with one known compound , Kopetdaghin C, were isolated from the root of F. latisecta.
  
  
  CONCLUSIONS
  In this research the structure of one new and one known sesquiterpene in the root of F. latisecta was elucidated.
authors: Biotechnology Ressearch Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, I. R. Iran.
authors: Mehrdad
authors: M
authors: Iranshahi
authors: Biotechnology Ressearch Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, I. R. Iran.
authors: Farjad
authors: F
authors: Amanolahi
authors: Max Planck Institute for Chemical Ecology, Beutenberg Campus, Jena, Germany.
authors: Bernd
authors: B
authors: Schneider