title: 5-year results comparing mineral trioxide aggregate and adhesive resin composite for root-end sealing in apical surgery.
abstract: BACKGROUND
  Recent meta-analyses of the outcome of apical surgery using modern techniques including microsurgical principles and high-power magnification have yielded higher rates of healing. However, the information is mainly based on 1- to 2-year follow-up data. The present prospective study was designed to re-examine a large sample of teeth treated with apical surgery after 5 years.
  
  
  METHODS
  Patients were recalled 5 years after apical surgery, and treated teeth were classified as healed or not healed based on clinical and radiographic examination. (The latter was performed independently by 3 observers). Two different methods of root-end preparation and filling (primary study parameters) were to be compared (mineral trioxide aggregate [MTA] vs adhesive resin composite [COMP]) without randomization.
  
  
  RESULTS
  A total of 271 patients and teeth from a 1-year follow-up sample of 339 could be re-examined after 5 years (dropout rate = 20.1%). The overall rate of healed cases was 84.5% with a significant difference (P = .0003) when comparing MTA (92.5%) and COMP (76.6%). The evaluation of secondary study parameters yielded no significant difference for healing outcome when comparing subcategories (ie, sex, age, type of tooth treated, post/screw, type of surgery).
  
  
  CONCLUSIONS
  The results from this prospective nonrandomized clinical study with a 5-year follow-up of 271 teeth indicate that MTA exhibited a higher healing rate than COMP in the longitudinal prognosis of root-end sealing.
authors: Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern, Bern, Switzerland. Electronic address: thomas.vonarx@zmk.unibe.ch.
authors: Thomas
authors: T
authors: von Arx
authors: Department of Preventive, Pediatric, and Restorative Dentistry, School of Dental Medicine, University of Bern, Bern, Switzerland; Private Practice limited to Endodontology, Bern, Switzerland.
authors: Stefan
authors: S
authors: Hänni
authors: Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern, Bern, Switzerland; Department of Oral and Maxillofacial Surgery, Copenhagen University Hospital, Denmark.
authors: Simon Storgård
authors: SS
authors: Jensen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017607:Aluminum Compounds / Q000627:therapeutic use*; D001047:Apicoectomy / Q000379:methods*; D017610:Calcium Compounds / Q000627:therapeutic use*; D002648:Child; D015331:Cohort Studies; D003188:Composite Resins / Q000627:therapeutic use*; D017220:Dentin-Bonding Agents / Q000627:therapeutic use; D004338:Drug Combinations; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D065228:Non-Randomized Controlled Trials as Topic; D010087:Oxides / Q000627:therapeutic use*; D010352:Patient Dropouts; D011446:Prospective Studies; D016300:Radiography, Bitewing; D012184:Retrograde Obturation / Q000379:methods*; D012387:Root Canal Filling Materials / Q000627:therapeutic use*; D017640:Silicates / Q000627:therapeutic use*; D016896:Treatment Outcome; D014945:Wound Healing / Q000502:physiology; D055815:Young Adult
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D003188:Composite Resins; D017220:Dentin-Bonding Agents; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate
keywords: Apical surgery; clinical comparative study; long-term follow-up; root-end filling