title: [Clinical applications of active fixation at the right ventricular outflow tract using a modified pacing leads model].
abstract: OBJECTIVE
  To assess the feasibility and safety of using the modified active fixation pacing leads model to pace the right ventricular outflow tract septum.
  
  
  METHODS
  A total of 136 patients undergoing artificial heart pacemaker implantation with active fixation pacing leads were randomized into two groups to receive conventional right ventricular outflow tract pacing (CRVOTP) or modified right ventricular outflow tract pacing (MRVOTP). The electrode lead wire core was modeled in a double-curved three-dimensional shape in CRVOTP group and in a J-shaped bend in MRVOTP group before fixation at the right ventricular outflow tract septum.
  
  
  RESULTS
  Right ventricular outflow tract septum pacing was achieved successfully in all the patients. None of patients experienced serious complications. No significant differences were found between the two groups in the number of times of electrode fixation, pacing thresholds, impedance, R wave height or QRS wave width during the operation, but MRVOTP was associated with a reduced time of X -ray exposure and operation (P<0.05) due to the convenience in electrode modeling and in passing the leads through the tricuspid annulus and the direct access to the right ventricular outflow tract septum. Postoperative follow-up of the patients showed no incidence of active fixation pacing lead dislocation and comparable pacing thresholds of the ventricular electrodes, impedance, R wave height and QRS wave width between the two groups.
  
  
  CONCLUSIONS
  Using the modified active fixation pacing leads model to pace the right ventricular outflow tract septum can reduce the time of X -ray exposure and operation with a low probability of lead damage.
authors: Department of Cardiology, First Affiliated Hospital, Guangdong University of Pharmacy, Guangzhou 510080, China. E-mail: gzzh@163.com.
authors: Zhihuan
authors: Z
authors: Zeng
authors: Silin
authors: S
authors: Chen
authors: Yanqun
authors: Y
authors: Zhao
authors: Wanxing
authors: W
authors: Zhou
authors: Wei
authors: W
authors: Zhang
authors: Guiping
authors: G
authors: Zhu
authors: Bowei
authors: B
authors: Li
authors: Yuliang
authors: Y
authors: Zhou
mesh_terms: D002304:Cardiac Pacing, Artificial; D004566:Electrodes; D006352:Heart Ventricles; D006801:Humans; D010138:Pacemaker, Artificial