title: Processed meat consumption and squamous cell carcinoma of the oesophagus in a large case-control study in Uruguay.
abstract: BACKGROUND
  The role of processed meat in the aetiology of squamous cell oesophageal cancer has been explored in detail.
  
  
  METHODS
  In the time period 1990-2005, a case-control study was conducted in Montevideo, Uruguay including 2,368 participants (876 cases of oesophageal cancer and 1,492 controls). Relative risks, approximated by the odds ratios, were estimated by multiple unconditional logistic regression.
  
  
  RESULTS
  Processed meat was positively associated with oesophageal cancer (upper quartile vs lower quartile OR 2.30, 95%CI 1.72-3.07), whereas salted meat intake was positively associated with squamous cell oesophageal cancer (OR 3.82, 95%CI 2.74-5.33). Finally other cured meats were positively associated with oesophageal cancer (OR 1.65, 95%CI 1.22- 2.22).
  
  
  CONCLUSIONS
  It could be concluded that processed meat consumption could be an important risk factor for the aetiology of squamous cell oesophageal cancer in Uruguay.
authors: Epidemiology Group, Department of Pathology, School of Medicine, University of the Republic, Montevideo, Uruguay E-mail : edestefani@gmail.com.
authors: Eduardo
authors: E
authors: De Stefani
authors: Paolo
authors: P
authors: Boffetta
authors: Alvaro Luis
authors: AL
authors: Ronco
authors: Hugo
authors: H
authors: Deneo-Pellegrini
authors: Pelayo
authors: P
authors: Correa
authors: Gisele
authors: G
authors: Acosta
authors: Maria
authors: M
authors: Mendilaharsu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology*; D016022:Case-Control Studies; D004938:Esophageal Neoplasms / Q000453:epidemiology*; D000077277:Esophageal Squamous Cell Carcinoma; D004947:Esophagus / Q000473:pathology; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D008297:Male; D008461:Meat Products / Q000009:adverse effects*; D008875:Middle Aged; D016017:Odds Ratio; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology; D012965:Sodium Chloride; D014583:Uruguay / Q000453:epidemiology
chemical_list: D012965:Sodium Chloride