title: Evaluation of the multi-element capabilities of collision/reaction cell inductively coupled plasma-mass spectrometry in wine analysis.
abstract: This work explores the multi-element capabilities of inductively coupled plasma-mass spectrometry with collision/reaction cell technology (CCT-ICP-MS) for the simultaneous determination of both spectrally interfered and non-interfered nuclides in wine samples using a single set of experimental conditions. The influence of the cell gas type (i.e. He, He+H2 and He+NH3), cell gas flow rate and sample pre-treatment (i.e. water dilution or acid digestion) on the background-equivalent concentration (BEC) of several nuclides covering the mass range from 7 to 238u has been studied. Results obtained in this work show that, operating the collision/reaction cell with a compromise cell gas flow rate (i.e. 4 mL min(-1)) improves BEC values for interfered nuclides without a significant effect on the BECs for non-interfered nuclides, with the exception of the light elements Li and Be. Among the different cell gas mixtures tested, the use of He or He+H2 is preferred over He+NH3 because NH3 generates new spectral interferences. No significant influence of the sample pre-treatment methodology (i.e. dilution or digestion) on the multi-element capabilities of CCT-ICP-MS in the context of simultaneous analysis of interfered and non-interfered nuclides was observed. Nonetheless, sample dilution should be kept at minimum to ensure that light nuclides could be quantified in wine. Finally, a direct 5-fold aqueous dilution is recommended for the simultaneous trace and ultra-trace determination of spectrally interfered and non-interfered elements in wine by means of CCT-ICP-MS. The use of the CCT is mandatory for interference-free ultra-trace determination of Ti and Cr. Only Be could not be determined when using the CCT due to a deteriorated limit of detection when compared to conventional ICP-MS.
authors: University of Alicante, Department of Analytical Chemistry, Nutrition and Food Sciences, PO Box 99, 03080 Alicante, Spain; Ghent University, Department of Analytical Chemistry, Krijgslaan 281-S12, 9000 Ghent, Belgium. Electronic address: guillermo.grindlay@ua.es.
authors: Guillermo
authors: G
authors: Grindlay
authors: University of Alicante, Department of Analytical Chemistry, Nutrition and Food Sciences, PO Box 99, 03080 Alicante, Spain.
authors: Juan
authors: J
authors: Mora
authors: Ghent University, Department of Analytical Chemistry, Krijgslaan 281-S12, 9000 Ghent, Belgium; Delft University of Technology, Faculty of Applied Sciences, Analytical Biotechnology, Julianalaan 67, 2628 BC Delft, The Netherlands.
authors: Margaretha T C
authors: MT
authors: de Loos-Vollebregt
authors: University of Alicante, Department of Analytical Chemistry, Nutrition and Food Sciences, PO Box 99, 03080 Alicante, Spain. Electronic address: frank.vanhaecke@ugent.be.
authors: Frank
authors: F
authors: Vanhaecke
mesh_terms: D000641:Ammonia; D002857:Chromium / Q000032:analysis; D004602:Elements; D005740:Gases; D006371:Helium; D006859:Hydrogen; D013058:Mass Spectrometry / Q000295:instrumentation* / Q000379:methods*; D015203:Reproducibility of Results; D014025:Titanium / Q000032:analysis; D014920:Wine / Q000032:analysis*
chemical_list: D004602:Elements; D005740:Gases; D002857:Chromium; D006371:Helium; D000641:Ammonia; D006859:Hydrogen; D014025:Titanium
keywords: Collision/reaction cell; ICP–MS; Multi-element analysis; Spectral interference; Wine