title: A Comparison of Dynamics in Two Models for the Spread of a Vector-Borne Disease.
abstract: In 2007, bluetongue virus (BTV) was introduced to both Denmark (DK) and the United Kingdom (UK). For this reason, simulation models were built to predict scenarios for future incursions. The DK and UK models have a common description of within-herd dynamics, but differ greatly in their descriptions of between-herd spread, one using an explicit representation of vector dispersal, the other a transmission kernel. Here, we compare model predictions for the dynamics of bluetongue in the UK, based on the 2007 incursion and vaccination rollout in 2008. We demonstrate how an agent-based model shows greater sensitivity to the level of vaccine uptake and has lower variability compared with a kernel-based model. However, a model using a transmission kernel requires less detailed data and is often faster.
authors: Department of Applied Mathematics and Computer Science, Technical University of Denmark, Lyngby, Denmark.|National Veterinary Institute, Technical University of Denmark, Frederiksberg C, Denmark.
authors: K
authors: K
authors: Graesbøll
authors: The Pirbright Institute, Woking, UK.
authors: T
authors: T
authors: Sumner
authors: National Veterinary Institute, Technical University of Denmark, Frederiksberg C, Denmark.
authors: C
authors: C
authors: Enøe
authors: Department of Applied Mathematics and Computer Science, Technical University of Denmark, Lyngby, Denmark.
authors: L E
authors: LE
authors: Christiansen
authors: The Pirbright Institute, Woking, UK.
authors: S
authors: S
authors: Gubbins
mesh_terms: D000818:Animals; D001819:Bluetongue / Q000453:epidemiology* / Q000517:prevention & control / Q000635:transmission; D001820:Bluetongue virus / Q000276:immunology / Q000302:isolation & purification*; D002417:Cattle; D002519:Ceratopogonidae / Q000821:virology; D003718:Denmark / Q000453:epidemiology; D007303:Insect Vectors / Q000821:virology; D008962:Models, Theoretical; D012756:Sheep; D006113:United Kingdom / Q000453:epidemiology; D014611:Vaccination / Q000662:veterinary
keywords: bluetongue; mathematical modelling; model comparison; spread dynamics; vector-borne disease