title: [Stimforte action on the main inflammation characteristics in experimental animals contaminated by Herpes simplex-1].
abstract: In the brain and lungs of the experimental animals contaminated by Herpes simplex-1 there were detected much higher levels of the thiobarbituric acid-stained lipid oxidation products and proteolytic activity, evident of the inflammation process. Stimforte lowered the inflammation indices to the level, close to that in the brain of the noninfected animals. Yet the drug provided lower titers of the virus in the brain, lungs and serum in the contaminated animals and arrested the infection process by stimulation of the immune system. The mechanism of the inflammation suppression is discussed.
authors: D G
authors: DG
authors: Mal'dov
authors: G A
authors: GA
authors: Galegov
authors: V L
authors: VL
authors: Andronova
authors: A V
authors: AV
authors: Il'ichev
authors: A P
authors: AP
authors: Bel'kov
mesh_terms: D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000276:immunology / Q000821:virology; D006561:Herpes Simplex / Q000188:drug therapy* / Q000276:immunology / Q000821:virology; D018259:Herpesvirus 1, Human / Q000187:drug effects* / Q000254:growth & development; D007155:Immunologic Factors / Q000494:pharmacology*; D056747:Immunomodulation; D007249:Inflammation / Q000188:drug therapy / Q000276:immunology / Q000821:virology; D015227:Lipid Peroxidation / Q000187:drug effects; D008168:Lung / Q000187:drug effects* / Q000276:immunology / Q000821:virology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D018384:Oxidative Stress; D059748:Proteolysis; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism; D019562:Viral Load / Q000187:drug effects; D014779:Virus Replication / Q000187:drug effects
chemical_list: D007155:Immunologic Factors; D017392:Thiobarbituric Acid Reactive Substances