title: Assessment of cervicovaginal vascular endothelial growth factor in predicting preterm delivery.
abstract: OBJECTIVE
  The aim of this study is to estimate the effectiveness of cervicovaginal vascular endothelial growth factor (VEGF) in predicting preterm delivery.
  
  
  METHODS
  Cervicovaginal VEGF was measured in 30 women who presented symptoms or signs of threatened preterm labor and the control group of 30 healthy pregnant patients by enzyme-linked immunoassay.
  
  
  RESULTS
  There was no statistically significant difference in cervicovaginal VEGF values between the threatened preterm labor group and the control group (P > 0.05). Similarly, no statistically significant difference was observed in terms of cervical length and cervicovaginal VEGF values between preterm and term-delivered groups (P > 0.05). Additionally, there was no correlation between cervicovaginal VEGF values and cervical length (P > 0.05) between the threatened preterm labor and the control groups.
  
  
  CONCLUSIONS
  No correlation was found between cervicovaginal VEGF values and the preterm delivery. However, we believe that the role of VEGF in preterm delivery needs to be investigated further in well-designed studies with larger samples.
authors: Department of Obstetrics and Gynecology, Faculty of Medicine, Uludağ University, Bursa, Turkey.
authors: Embiye
authors: E
authors: Yilmaz
authors: Emin
authors: E
authors: Ustunyurt
authors: Sakir
authors: S
authors: Kucukkomurcu
authors: Ferah
authors: F
authors: Budak
authors: Guven
authors: G
authors: Ozkaya
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000378:metabolism; D054791:Cervical Length Measurement; D002584:Cervix Uteri / Q000000981:diagnostic imaging / Q000378:metabolism*; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D009092:Mucous Membrane / Q000378:metabolism*; D007752:Obstetric Labor, Premature / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism; D011237:Predictive Value of Tests; D011247:Pregnancy; D011296:Prenatal Diagnosis; D011446:Prospective Studies; D013499:Surface Properties; D014421:Turkey; D015854:Up-Regulation; D014621:Vagina / Q000378:metabolism*; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism*; D055815:Young Adult
chemical_list: D015415:Biomarkers; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A
keywords: cervical length; labor; preterm; vascular endothelial growth factor