title: Cancers of the anal canal: diagnosis, treatment and future strategies.
abstract: Anal cancer is an uncommon cancer; however, it is rising in incidence. There is confusion regarding nomenclature and the distinction between anal canal cancer and anal margin cancer. This article discusses the modern definition, etiology and staging of anal canal and anal margin cancers. Modern chemotherapy and radiotherapy regimens are discussed, in addition to modern imaging and radiotherapy techniques. Future preventative strategies and potential novel treatments are discussed.
authors: Department of Colorectal Surgery, Leicester Royal Infirmary, Infirmary Square, Leicester, LE1 5WW, UK.
authors: Emma
authors: E
authors: Bown
authors: Vikas
authors: V
authors: Shah
authors: Thiagarajan
authors: T
authors: Sridhar
authors: Kirsten
authors: K
authors: Boyle
authors: David
authors: D
authors: Hemingway
authors: Justin M
authors: JM
authors: Yeung
mesh_terms: D001005:Anus Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000401:mortality / Q000628:therapy*; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D011379:Prognosis; D012307:Risk Factors
keywords: anal canal cancer; anal margin cancer; human papillomavirus; salvage APER