title: Outcomes of shipped live donor kidney transplants compared with traditional living donor kidney transplants.
abstract: The disparity between kidney transplant candidates and donors necessitates innovations to increase organ availability. Transporting kidneys allows for living donors and recipients to undergo surgery with a familiar transplant team, city, friends, and family. The effect of shipping kidneys and prolonged cold ischemia time (CIT) with living donor transplantation outcomes is not clearly known. This retrospective matched (age, gender, race, and year of procedure) cohort study compared allograft outcomes for shipped live donor kidney transplants and nonshipped living donor kidney transplants. Fifty-seven shipped live donor kidneys were transplanted from 31 institutions in 26 cities. The mean shipping distance was 1634 miles (range 123-2811) with mean CIT of 12.1 ± 2.8 h. The incidence of delayed graft function in the shipped cohort was 1.8% (1/57) compared to 0% (0/57) in the nonshipped cohort. The 1-year allograft survival was 98% in both cohorts. There were no significant differences between the mean serum creatinine values or the rates of serum creatinine decline in the immediate postoperative period even after adjusted for gender and differences in recipient and donor BMI. Despite prolonged CITs, outcomes for shipped live donor kidney transplants were similar when compared to matched nonshipped living donor kidney transplants.
authors: Department of Urology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
authors: Eric G
authors: EG
authors: Treat
authors: Eric T
authors: ET
authors: Miller
authors: Lorna
authors: L
authors: Kwan
authors: Sarah E
authors: SE
authors: Connor
authors: Sally L
authors: SL
authors: Maliski
authors: Elisabeth M
authors: EM
authors: Hicks
authors: Kristen C
authors: KC
authors: Williams
authors: Lauren A
authors: LA
authors: Whitted
authors: Hans A
authors: HA
authors: Gritsch
authors: Suzanne M
authors: SM
authors: McGuire
authors: Thomas D
authors: TD
authors: Mone
authors: Jeffrey L
authors: JL
authors: Veale
mesh_terms: D000328:Adult; D015331:Cohort Studies; D050377:Cold Ischemia; D003404:Creatinine / Q000097:blood; D051799:Delayed Graft Function; D005260:Female; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D009927:Tissue and Organ Procurement; D014186:Transportation; D061349:Unrelated Donors
chemical_list: D003404:Creatinine
keywords: cold ischemia; delayed graft function; kidney transplantation; transport