title: Intact IL-12 signaling is necessary for the generation of human natural killer cells with enhanced effector function after restimulation.
authors: Laboratory of Molecular and Developmental Immunology, Division of Monoclonal Antibodies, Center for Drug Evaluation and Research, Food and Drug Administration, Bethesda, Md.
authors: Venkateswara R
authors: VR
authors: Simhadri
authors: Laboratory of Molecular and Developmental Immunology, Division of Monoclonal Antibodies, Center for Drug Evaluation and Research, Food and Drug Administration, Bethesda, Md.
authors: John L
authors: JL
authors: Mariano
authors: BioCruces Health Research Institute, Barakaldo, Spain.
authors: Olatz
authors: O
authors: Zenarruzabeitia
authors: University of Wisconsin School of Medicine and Public Health, Madison, Wis.
authors: Christine M
authors: CM
authors: Seroogy
authors: Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
authors: Steven M
authors: SM
authors: Holland
authors: Immunology Service, Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Md.
authors: Hye Sun
authors: HS
authors: Kuehn
authors: Primary Immunodeficiency Clinic, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
authors: Sergio D
authors: SD
authors: Rosenzweig
authors: Laboratory of Molecular and Developmental Immunology, Division of Monoclonal Antibodies, Center for Drug Evaluation and Research, Food and Drug Administration, Bethesda, Md; BioCruces Health Research Institute, Barakaldo, Spain; Ikerbasque, Basque Foundation for Science, Bilbao, Spain. Electronic address: francisco.borregorabasco@osakidetza.net.
authors: Francisco
authors: F
authors: Borrego
mesh_terms: D002478:Cells, Cultured; D006801:Humans; D018664:Interleukin-12 / Q000276:immunology*; D007694:Killer Cells, Natural / Q000166:cytology / Q000276:immunology*; D015398:Signal Transduction / Q000276:immunology*
chemical_list: D018664:Interleukin-12