title: The association of thyroid nodule with non-iodized salt among Chinese children.
abstract: OBJECTIVE
  The controversy that iodized salt may increase the risk of thyroid disorders has been aroused in China during the past decade. Most of studies focused on adult rather than children. We aimed to explore whether iodized salt was associated with an increased risk of thyroid nodule in Chinese children.
  
  
  METHODS
  The cross-sectional study was conducted in Hangzhou, China, in 2010. Iodized salt intake, urine iodine concentration (UIC) and thyroid nodule (by ultrasonography) were measured in 3026 children. The associations of iodized salt with thyroid nodule were evaluated using multiple logistic regression models.
  
  
  RESULTS
  The prevalence of thyroid nodule was 10.59% among Chinese children. Girls (11.89%) had higher prevalence of thyroid nodule than boys (9.26%). No significant association was observed between type of salt and thyroid nodule in pooled samples, boys and girls, respectively. Similar associations were observed between UIC and thyroid nodule. There was no significant association between milk consumption and thyroid nodule as well.
  
  
  CONCLUSIONS
  The present study indicated that non-iodized salt may not increase the risk of thyroid nodules among Chinese children. Similar associations were observed between milk consumption, UIC and thyroid nodules.
authors: Department of Endemic Diseases Control and Prevention, Hangzhou Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
authors: Weimin
authors: W
authors: Xu
authors: Department of Epidemiology and Health Statistics, School of Public Health, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Clinical Epidemiology and Biostatistics Center, The Second Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou, Zhejiang, China.
authors: Zexin
authors: Z
authors: Chen
authors: Department of Epidemiology and Health Statistics, School of Public Health, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
authors: Hui
authors: H
authors: Liu
authors: Department of Endemic Diseases Control and Prevention, Hangzhou Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
authors: Liangliang
authors: L
authors: Huo
authors: Department of Endemic Diseases Control and Prevention, Hangzhou Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
authors: Yangmei
authors: Y
authors: Huang
authors: Department of Endemic Diseases Control and Prevention, Hangzhou Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
authors: Xingyi
authors: X
authors: Jin
authors: Department of Endemic Diseases Control and Prevention, Hangzhou Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
authors: Jin
authors: J
authors: Deng
authors: Department of Endemic Diseases Control and Prevention, Hangzhou Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
authors: Sujuan
authors: S
authors: Zhu
authors: Department of Epidemiology and Health Statistics, School of Public Health, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
authors: Wen
authors: W
authors: Jin
authors: Department of Epidemiology and Health Statistics, School of Public Health, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
authors: Shanchun
authors: S
authors: Zhang
authors: Department of Epidemiology and Health Statistics, School of Public Health, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
authors: Yunxian
authors: Y
authors: Yu
mesh_terms: D002648:Child; D002681:China; D005260:Female; D006801:Humans; D007455:Iodine / Q000032:analysis; D008297:Male; D008875:Middle Aged; D012965:Sodium Chloride / Q000009:adverse effects*; D016606:Thyroid Nodule / Q000139:chemically induced*
chemical_list: D012965:Sodium Chloride; D007455:Iodine