title: Effect of quaternization degree on physiochemical and biological activities of chitosan from squid pens.
abstract: Chitosan was prepared by alkaline N-deacetylation of β-chitin from squid pens, and N-(2-hydroxy) propyl-3-trimethyl ammonium chitosan chloride (HTCC) derivatives, with different degrees of quaternization (DQ) ranging from 0.77 to 1.06, were synthesized. It was identified by FT-IR, 1H NMR and XRD analysis. All of the HTCC showed good water solubility in a wide pH range. The moisture absorption and retention abilities of all the HTCC were much better than that of the chitosan. The moisture absorption and retention values of all the HTCC at 43% RH for 24 h were above 49% and 92%, respectively. The scavenging ability of HTCC against hydroxyl and ABTS radicals improved with increasing concentration. The effectiveness of HTCC against hydroxyl radicals was lower than that of chitosan. These results indicated that HTCC, which has a much better moisture absorption and retention capacity, may act as a potential moisturizer in vitro.
authors: Key Laboratory of Agricultural Products Chemical and Biological Processing Technology of Zhejiang Province, School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, PR China. Electronic address: hjun79@gmail.com.
authors: Jun
authors: J
authors: Huang
authors: Department of Food Science, Zhejiang University of Technology, Hangzhou 310014, PR China.
authors: Zhen-Hua
authors: ZH
authors: Cheng
authors: Key Laboratory of Agricultural Products Chemical and Biological Processing Technology of Zhejiang Province, School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, PR China.
authors: Hai-Hua
authors: HH
authors: Xie
authors: Key Laboratory of Agricultural Products Chemical and Biological Processing Technology of Zhejiang Province, School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, PR China.
authors: Jin-Yan
authors: JY
authors: Gong
authors: Key Laboratory of Agricultural Products Chemical and Biological Processing Technology of Zhejiang Province, School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, PR China.
authors: Jian
authors: J
authors: Lou
authors: Key Laboratory of Agricultural Products Chemical and Biological Processing Technology of Zhejiang Province, School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, PR China.
authors: Qing
authors: Q
authors: Ge
authors: Key Laboratory of Agricultural Products Chemical and Biological Processing Technology of Zhejiang Province, School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, PR China.
authors: Yong-Jiang
authors: YJ
authors: Wang
authors: Key Laboratory of Agricultural Products Chemical and Biological Processing Technology of Zhejiang Province, School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, PR China.
authors: Yuan-Feng
authors: YF
authors: Wu
authors: Key Laboratory of Agricultural Products Chemical and Biological Processing Technology of Zhejiang Province, School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, PR China.
authors: Shi-Wang
authors: SW
authors: Liu
authors: Department of Food Science, Zhejiang University of Technology, Hangzhou 310014, PR China.
authors: Pei-Long
authors: PL
authors: Sun
authors: Key Laboratory of Agricultural Products Chemical and Biological Processing Technology of Zhejiang Province, School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, PR China. Electronic address: zjhzmjw@163.com.
authors: Jian-Wei
authors: JW
authors: Mao
mesh_terms: D065966:Absorption, Physicochemical; D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology; D055598:Chemical Phenomena; D048271:Chitosan / Q000737:chemistry* / Q000494:pharmacology*; D049832:Decapodiformes / Q000737:chemistry*; D016166:Free Radical Scavengers / Q000737:chemistry / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D019906:Nuclear Magnetic Resonance, Biomolecular; D012995:Solubility; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D000975:Antioxidants; D016166:Free Radical Scavengers; D048271:Chitosan
keywords: Chitosan; Quaternization degree; β-Chitin