title: Pd-catalyzed [3+2] cycloaddition of ketoimines with alkynes via directed sp³ C-H bond activation.
abstract: The Pd(II)-catalyzed oxidative [3+2] cycloaddition of N-(2-pyridyl) ketoimines with internal alkynes has been developed. The transformation is tolerant of extensive substitution on halogen, alkene, alkyne, hydroxyl, aryl and acyl groups, and allows facile assembly of multisubstituted pyrroles.
authors: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510641, China. zengwei@scut.edu.cn.
authors: Ying
authors: Y
authors: Xie
authors: Tengfei
authors: T
authors: Chen
authors: Shaomin
authors: S
authors: Fu
authors: Xing-Shu
authors: XS
authors: Li
authors: Yuanfu
authors: Y
authors: Deng
authors: Huanfeng
authors: H
authors: Jiang
authors: Wei
authors: W
authors: Zeng
mesh_terms: D000475:Alkenes / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D061565:Cycloaddition Reaction; D006219:Halogens / Q000737:chemistry; D006859:Hydrogen / Q000737:chemistry; D007097:Imines / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry
chemical_list: D000475:Alkenes; D000480:Alkynes; D006219:Halogens; D007097:Imines; D011758:Pyrroles; D010165:Palladium; D002244:Carbon; D006859:Hydrogen