title: Reusable and robust high sensitive non-enzymatic glucose sensor based on Ni(OH)₂ nanoparticles.
abstract: Nickel hydroxide nanoparticles were successfully electrodeposited on graphite electrode (Gr/NiONP) and employed as a robust non-enzymatic glucose sensor. The results of cyclic voltammetry (CV) and chronoamperometry demonstrated that the Gr/NiONP electrode displayed high electrocatalytic activity toward glucose. The oxidation current is directly related to the glucose concentration from 1 μM to 15 mM. Besides, the glucose sensor displayed high sensitivity (2400 μA mM(-1) cm(-2)) with a detection limit of 0.53 μM (S/N=3) in basic solution. Moreover, the sensor showed excellent selectivity, reproducibility and stability properties. The relative standard deviation is 1.2% for 10 successive measurements in 16 μM glucose. Interestingly, the signal for glucose was maintained at 95% of its initial value even after 6 months of storage under ambient conditions. Gr/NiONP electrode has also been tested to detect glucose in human serum with satisfactory results.
authors: Chemistry & Chemical Engineering Research Center of Iran, P.O. Box 14335-186, Tehran, Iran. Electronic address: makiani@ccerci.ac.ir.
authors: M A
authors: MA
authors: Kiani
authors: Chemistry & Chemical Engineering Research Center of Iran, P.O. Box 14335-186, Tehran, Iran.
authors: M Abbasnia
authors: MA
authors: Tehrani
authors: Chemistry & Chemical Engineering Research Center of Iran, P.O. Box 14335-186, Tehran, Iran.
authors: H
authors: H
authors: Sayahi
mesh_terms: D015374:Biosensing Techniques; D005947:Glucose / Q000032:analysis*; D006878:Hydroxides / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D053758:Nanoparticles; D009532:Nickel / Q000737:chemistry*; D010084:Oxidation-Reduction; D015203:Reproducibility of Results; D014961:X-Ray Diffraction
chemical_list: D006878:Hydroxides; C037473:nickel hydroxide; D009532:Nickel; D005947:Glucose
keywords: Glucose; Graphite; Nanoparticle; Nickel hydroxide; Non-enzymatic sensor