title: Body mass index and response to a multidisciplinary treatment of fibromyalgia.
abstract: The purpose of this study is to determine whether there are some differences in the treatment responses to a multidisciplinary fibromyalgia (FM) treatment related with the baseline body mass index (BMI) of the participants. Inclusion criteria consisted of female sex, a diagnosis of FM (American College of Rheumatology criteria), age between 18 and 60 years, and between 3 and 8 years of schooling. Baseline BMI was determined, and patients were randomly assigned to one of the two treatment conditions: conventional pharmacologic treatment or multidisciplinary treatment. Outcome measures were pain intensity, functionality, catastrophizing, psychological distress, health-related quality of life, and sleep disturbances. One hundred thirty patients participated in the study. No statistical significant differences regarding pre-treatment outcomes were found among the different BMI subgroups, and between the two experimental conditions for each BMI category. General linear model analysis showed a significant interaction group treatment × time in pain intensity (p < .01), functionality (p < .0001), catastrophizing (p < .01), psychological distress (p < .0001), sleep index problems (p < .0001), and health-related quality of life (p < .05). No significant interactions were found in BMI × time, and in BMI × group treatment × time. There are not differences among normal weight, overweight and obese patients with FM regarding their response to a multidisciplinary treatment programme for FM which combines pharmacological treatment, education, physical therapy and cognitive behavioural therapy.
authors: Pain Clinic, Hospital Universitari de Tarragona Joan XXIII, C/Doctor Mallafré Guasch, 4, 43007, Tarragona, Spain, antonicastel.hj23.ics@gencat.cat.
authors: Antoni
authors: A
authors: Castel
authors: Sonia
authors: S
authors: Castro
authors: Ramon
authors: R
authors: Fontova
authors: Maria José
authors: MJ
authors: Poveda
authors: Rosalia
authors: R
authors: Cascón-Pereira
authors: Salvador
authors: S
authors: Montull
authors: Anna
authors: A
authors: Padrol
authors: Rami
authors: R
authors: Qanneta
authors: Maria
authors: M
authors: Rull
mesh_terms: D000293:Adolescent; D000328:Adult; D000700:Analgesics / Q000627:therapeutic use*; D000928:Antidepressive Agents / Q000627:therapeutic use*; D015992:Body Mass Index; D058443:Catastrophization / Q000150:complications / Q000523:psychology; D015928:Cognitive Behavioral Therapy; D003131:Combined Modality Therapy; D005260:Female; D005356:Fibromyalgia / Q000150:complications / Q000523:psychology / Q000628:therapy*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use*; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D050177:Overweight / Q000150:complications; D010147:Pain Measurement; D010348:Patient Care Team; D026741:Physical Therapy Modalities; D011379:Prognosis; D011788:Quality of Life; D012893:Sleep Wake Disorders / Q000150:complications; D013315:Stress, Psychological / Q000150:complications / Q000523:psychology; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000700:Analgesics; D000928:Antidepressive Agents; D006993:Hypnotics and Sedatives