title: Additional perspectives on chronic kidney disease of unknown aetiology (CKDu) in Sri Lanka--lessons learned from the WHO CKDu population prevalence study.
abstract: The recent emergence of an apparently new form of chronic kidney disease of unknown aetiology (CKDu) has become a serious public health crisis in Sri Lanka. CKDu is slowly progressive, irreversible, and asymptomatic until late stages, and is not attributable to hypertension, diabetes, or other known aetiologies. In response to the scope and severity of the emerging CKDu health crisis, the Sri Lanka Ministry of Health and the World Health Organization initiated a collaborative research project from 2009 through 2012 to investigate CKDu prevalence and aetiology. The objective of this paper is to discuss the recently published findings of this investigation and present additional considerations and recommendations that may enhance subsequent investigations designed to identify and understand CKDu risk factors in Sri Lanka or other countries.
authors: RTI International, Center for Health and Environmetnal Modeling, 3040 East Cornwallis Rd, Research Triangle Park, NC 27709-2194, USA. jredmon@rti.org.
authors: Jennifer Hoponick
authors: JH
authors: Redmon
authors: Myles F
authors: MF
authors: Elledge
authors: Donna S
authors: DS
authors: Womack
authors: Rajitha
authors: R
authors: Wickremashinghe
authors: Kamani P
authors: KP
authors: Wanigasuriya
authors: Roshini J
authors: RJ
authors: Peiris-John
authors: Joseph
authors: J
authors: Lunyera
authors: Kristin
authors: K
authors: Smith
authors: James H
authors: JH
authors: Raymer
authors: Keith E
authors: KE
authors: Levine
mesh_terms: D003906:Developing Countries / Q000706:statistics & numerical data*; D004781:Environmental Exposure / Q000706:statistics & numerical data*; D005260:Female; D000075322:Heavy Metal Poisoning; D006801:Humans; D008297:Male; D011041:Poisoning / Q000453:epidemiology*; D019216:Metals, Heavy
chemical_list: D019216:Metals, Heavy