title: [Characteristics of regulatory system in children exposed to the environmental chemical factors].
abstract: In children residing in areas with a high content of a number of aromatic hydrocarbons in ambient air and organochlorine compounds in drinking water there were studied the blood levels of these compounds, as well as the assessment of the indices of the immune and neuroendocrine systems was performed. The higher blood content of phenol and formaldehyde has been established and there was identified an array of organochlorine and aromatic compounds not detected in the control group children. In the blood of the children of a study group there was found an imbalance of indices of cellular components of innate and adaptive immunity, pro- and anti-inflammatory cytokines, as well as increased concentrations of free thyroxine and serotonin in the blood serum, which indicates to a change in the functions of regulatory systems in children exposed to organochlorine and aromatic compounds.
authors: D V
authors: DV
authors: Lanin
authors: N V
authors: NV
authors: Zaytseva
authors: M A
authors: MA
authors: Zamlyanova
authors: O V
authors: OV
authors: Dolgikh
authors: D G
authors: DG
authors: Dianova
mesh_terms: D000393:Air Pollutants / Q000009:adverse effects / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D060766:Drinking Water / Q000032:analysis*; D004703:Endocrine System / Q000187:drug effects; D004781:Environmental Exposure / Q000009:adverse effects / Q000032:analysis*; D004784:Environmental Monitoring / Q000379:methods; D005260:Female; D006801:Humans; D006841:Hydrocarbons, Aromatic / Q000009:adverse effects / Q000032:analysis* / Q000097:blood; D006843:Hydrocarbons, Chlorinated / Q000009:adverse effects / Q000032:analysis* / Q000097:blood; D007107:Immune System / Q000187:drug effects; D008297:Male; D012426:Russia / Q000453:epidemiology
chemical_list: D000393:Air Pollutants; D060766:Drinking Water; D006841:Hydrocarbons, Aromatic; D006843:Hydrocarbons, Chlorinated