title: Routine one-stage exchange for chronic infection after total hip replacement.
abstract: OBJECTIVE
  We hypothesized that a routine one-stage exchange for treatment of chronically infected total hip replacement (THR) will lead to (1) a higher rate of infection recurrence and (2) a poorer hip outcome than the published rates after two-stage exchange.
  
  
  METHODS
  Sixty-five cases have been treated consecutively with one-stage exchange. All patients have been followed for a period of three to six years or until death or infection recurrence.
  
  
  RESULTS
  The five-year rate for infection recurrence was 16%. The five-year survival rate for recurrence of the index infection was 8%. Forty-two percent of the hips had a good or excellent PMA score, and 46% a good or excellent OH score.
  
  
  CONCLUSIONS
  Routine one-stage exchange was not associated with a higher recurrence rate and a poorer hip function than previously published series of two-stage exchange. Therefore, there is little support to choose two-stage exchange as the routine treatment for management of chronically infected THR.
authors: Centre for Orthopaedic and Hand Surgery, University Hospital Strasbourg, 10 avenue Baumann, 67400, Illkirch, France, jean-yves.jenny@chru-strasbourg.fr.
authors: Jean-Yves
authors: JY
authors: Jenny
authors: Régis
authors: R
authors: Lengert
authors: Yann
authors: Y
authors: Diesinger
authors: Jeannot
authors: J
authors: Gaudias
authors: Cyril
authors: C
authors: Boeri
authors: Jean-François
authors: JF
authors: Kempf
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006621:Hip Joint / Q000382:microbiology / Q000601:surgery*; D006622:Hip Prosthesis / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000209:etiology / Q000601:surgery*; D012008:Recurrence; D012189:Retrospective Studies; D015996:Survival Rate; D014945:Wound Healing
chemical_list: D000900:Anti-Bacterial Agents