title: Regioselective air oxidation of sulfides to O,S-acetals in a bubble column.
abstract: In this paper the use of a bubble column for a metal-free, selective oxidation of α-alkylthio-imines to O,S-acetals is presented. During the synthesis, which is straightforward to perform, the sulfides are oxidized to α-alkoxy- or, respectively, α-hydroxysulfide by adding activated carbon in the presence of atmospheric oxygen only. We show that the use of the bubble column, which is unusual on laboratory scale, improves the efficiency of the reaction in comparison to common laboratory techniques. As atmospheric oxygen alone is used for oxidation, this method is cost saving, environmentally friendly, and safe.
authors: Carl von Ossietzky Universität Oldenburg, Fakultät für Mathematik und Naturwissenschaften, Institut für Chemie, Carl-von-Ossietzky-Str. 9-11, 26129 Oldenburg (Germany) http://www.martens.chemie.uni-oldenburg.de.
authors: Fabian
authors: F
authors: Brockmeyer
authors: Jürgen
authors: J
authors: Martens
mesh_terms: D000080:Acetals / Q000737:chemistry*; D000388:Air; D002384:Catalysis; D010084:Oxidation-Reduction; D013237:Stereoisomerism; D013379:Substrate Specificity; D013440:Sulfides / Q000737:chemistry*
chemical_list: D000080:Acetals; D013440:Sulfides
keywords: acetals; green chemistry; o,s-hemiacetals; oxidation; synthesis