title: Ultrasonics in isocyanide-based multicomponent reactions: a new, efficient and fast method for the synthesis of fully substituted 1,3,4-oxadiazole derivatives under ultrasound irradiation.
abstract: A fast and convenient approach to the synthesis of fully substituted 1,3,4-oxadiazoles via three-component reaction of aromatic carboxylic acids, acenaphthoquinone, and (N-isocyanimino)triphenylphosphorane under ultrasound irradiation is described. Furthermore, a series of compounds were synthesized and characterized by melting point, IR, NMR and MS. Utilization of easy reaction conditions, very high to excellent yields, and short reaction times makes this manipulation potentially very useful.
authors: Department of Chemistry, University of Zanjan, P O Box 45195-313, Zanjan, Iran.
authors: Morteza
authors: M
authors: Rouhani
authors: Department of Chemistry, University of Zanjan, P O Box 45195-313, Zanjan, Iran. Electronic address: aliramazani@gmail.com.
authors: Ali
authors: A
authors: Ramazani
authors: School of Mechanical Engineering, Yeungnam University, Gyeongsan 712-749, Republic of Korea. Electronic address: swjoo@yu.ac.kr.
authors: Sang Woo
authors: SW
authors: Joo
keywords: (N-Isocyanimino)triphenylphosphorane; Acenaphthoquinone; Aromatic carboxylic acids; Intramolecular aza-Wittig reaction; Isocyanide; Ultrasound