title: Preliminary experience with squid: a new liquid embolizing agent for AVM, AV fistulas and tumors.
abstract: OBJECTIVE
  The aim of the present study was to analyze our experience with a new liquid embolic agent, Squid, for the treatment of cerebral vascular lesions.
  
  
  METHODS
  We present 28 patients who were treated with two formulations of Squid (Squid 18 and Squid 12). The lesions included 16 arteriovenous malformation (AVM)s (Spetzler-Martin grade 2 in 8, 3 in 6 and 4 in 2), 9 arteriovenous (AV) fistulas, 2 tumors (glomus tumor and angiofibroma) and 1 AICA aneurysm. Of the 9 patients presenting with hemorrhage, 6 were AVM, 2 were AVF and 1 was aneurysm.
  
  
  RESULTS
  The total obliteration rate of the AVMs was 37.5%. Fistulas were closed completely after combined treatment with surgery in 6 out of 9 patients, and one was sent to radiotherapy. There was no mortality. Two reported hemorrhages and thromboembolic complications resulted in permanent deficits in 3 patients. Pathologic examination revealed mild inflammatory reaction with infiltration of polymorphonuclear cells in 5 patients in whom surgery was performed immediately after embolization. Technical problems such as rupture, inability to remove or premature occlusion of the microcatheter related to the embolic agent were not recorded.
  
  
  CONCLUSIONS
  Squid is a safe and effective embolic agent for treatment of cerebral AVMs, AV fistulas, tumors and aneurysms with satisfactory obliteration rate.
authors: Ankara Numune Education and Research Hospital, Department of Radiology, Ankara, Turkey.
authors: Ilkay
authors: I
authors: Akmangit
authors: Ergun
authors: E
authors: Daglioglu
authors: Tunca
authors: T
authors: Kaya
authors: Fatih
authors: F
authors: Alagoz
authors: Mert
authors: M
authors: Sahinoglu
authors: Ahmet
authors: A
authors: Peker
authors: Shehram
authors: S
authors: Derakshani
authors: Dogan
authors: D
authors: Dede
authors: Deniz
authors: D
authors: Belen
authors: Anil
authors: A
authors: Arat
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D018322:Angiofibroma / Q000601:surgery; D001164:Arteriovenous Fistula / Q000473:pathology / Q000628:therapy*; D001932:Brain Neoplasms / Q000473:pathology / Q000628:therapy*; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D005918:Glomus Tumor / Q000601:surgery; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011145:Polyvinyls / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D011145:Polyvinyls; C020320:ethylene-vinyl alcohol copolymer