title: [Application of exogenous surfactant and recruitment maneuver in newborns with respiratory distress-syndrome].
abstract: Respiratory distress-syndrome (RDS) in newborns is a one of the most frequent critical conditions of neonatal period requires the use of invasive methods of respiratory support.
  
  
  OBJECTIVE
  To define an efficiency of complex application of exogenous surfactant and recruitment maneuver in newborns with RDS.
  
  
  METHODS
  30 newborns with RDS and progressive hypoxemia were included in the study. Average mass of body was 1575 grams. In 11 newborns RDS was accompanied severe hypoxemia and required the application of recruitment maneuver and exogenous surfactant administration.
  
  
  RESULTS
  Application of recruitment maneuver with exogenous surfactant administration allow to improve gas exchange and blood oxygenation in newborns with RDS (PaO2 54 vs 39 mmHg; SpO2 95 vs 90% and blood pH 7.34 vs 7.28). Application of recruitment maneuver with exogenous surfactant administration decrease number of complications and improve outcomes.
authors: Yu S
authors: YS
authors: Aleksandrovich
authors: O A
authors: OA
authors: Pechueva
authors: K V
authors: KV
authors: Pshenisnov
mesh_terms: D018450:Disease Progression; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000188:drug therapy* / Q000209:etiology; D007231:Infant, Newborn; D008297:Male; D010100:Oxygen / Q000378:metabolism*; D011650:Pulmonary Alveoli / Q000378:metabolism; D011659:Pulmonary Gas Exchange; D011663:Pulmonary Surfactants / Q000627:therapeutic use*; D012127:Respiratory Distress Syndrome, Newborn / Q000188:drug therapy* / Q000503:physiopathology; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D011663:Pulmonary Surfactants; D010100:Oxygen