title: [Jatropha seed oils extracted by different methods and their effect on killing cercaria of Schistosoma japonicum].
abstract: OBJECTIVE
  To evaluate the effect of Jatropha seed oils extracted by different methods on killing cercaria of Schistosomajaponicum so as to screen the optimum process and formulations.
  
  
  METHODS
  The cercaria directly contacting tests with Jatropha seed oils extracted by 6 different extraction processes were carried out, and the mouse immediate contacting cercaria infection trials with different formulations of Jatropha seed oil and various additives were performed.
  
  
  RESULTS
  With 95% ethanol, the ratio of material to liquid being 1:8, and 2 h extraction, the oil extraction rate was 30.7%. The cercaria directly contacting tests showed that 6 kinds of Jatropha seed oil killed all cercaria within 30 min. In the mouse immediate contacting cercaria infection trials, the worm declined rate of Jatropha seed oil liquid was 70.97%, and the worm declined rate of the sample added with benzyl benzoate was 58.87%, and the worm declined rate of the sample added with laurocapram was 77.42%. The worm declined rate of the samples added with benzyl benzoate, dibutyl phthalate and laurocapram was 100%.
  
  
  CONCLUSIONS
  The process with 95% ethanol, the ratio of material to liquid being 1:8, and 2 h extraction is the optimum, and the Jatropha seed oil has a good killing schistosome cercaria effect.
authors: Ping
authors: P
authors: Yi
authors: Qu-zhi
authors: QZ
authors: Yu
authors: Wen
authors: W
authors: Qu
authors: Ying
authors: Y
authors: Xia
authors: Wen-hua
authors: WH
authors: Cheng
authors: Shuang
authors: S
authors: Li
authors: Qin-qi
authors: QQ
authors: Liu
authors: Yao
authors: Y
authors: Tong
authors: Li-jun
authors: LJ
authors: Tang
mesh_terms: D000818:Animals; D058487:Cercaria / Q000187:drug effects*; D005591:Chemical Fractionation / Q000379:methods*; D005260:Female; D031286:Jatropha / Q000737:chemistry*; D008297:Male; D051379:Mice; D010938:Plant Oils / Q000302:isolation & purification* / Q000494:pharmacology*; D012549:Schistosoma japonicum / Q000187:drug effects*; D012639:Seeds / Q000737:chemistry*
chemical_list: D010938:Plant Oils