title: Retinal sensitivity assessed by microperimetry and corresponding retinal structure and thickness in resolved central serous chorioretinopathy.
abstract: OBJECTIVE
  To investigate the relationship between retinal sensitivity (RS) assessed by microperimetry (MP) and retinal structural changes in patients with resolved central serous chorioretinopathy (CSC).
  
  
  METHODS
  Spectral domain optical coherence tomography (OCT) examination and MP tests were performed in patients with resolved CSC. Point-to-point correlation was performed between RS and corresponding retinal structural changes using Pearson's correlation analysis. In addition, in a 1-mm zone in the central fovea, a correlation was calculated between the mean RS and the mean central retinal thickness (CRT).
  
  
  RESULTS
  Eighty-four eyes were analyzed. The total number of MP test points was 1092 (84 eyes × 13 points). The mean RS and retinal point thickness (RPT) of all test points were 13.53±3.84 dB and 208.6±48.0 μm, respectively. The RS and RPT were significantly decreased in the test points with loss of the ellipsoid portion of the inner segments (EPIS) (P<0.0001). Within the 1-mm foveal center zone, there was a significant correlation between mean RS and mean CRT (r=0.432, P<0.0001) and between RS and the corresponding RPT (r=0.339, P<0.0001).
  
  
  CONCLUSIONS
  RS was dependent on the status of the EPIS in patients with resolved CSC. The correlation between mean RS and mean CRT was compatible with the point-to-point correlation between RS and the corresponding RPT.
authors: Korea University College of Medicine, Seoul, Korea.
authors: H W
authors: HW
authors: Chung
authors: Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea.
authors: C M
authors: CM
authors: Yun
authors: Department of Ophthalmology, Chung-Ang University College of Medicine, Seoul, Korea.
authors: J T
authors: JT
authors: Kim
authors: Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea.
authors: S-W
authors: SW
authors: Kim
authors: Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea.
authors: J
authors: J
authors: Oh
authors: Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea.
authors: K
authors: K
authors: Huh
mesh_terms: D000328:Adult; D056833:Central Serous Chorioretinopathy / Q000175:diagnosis / Q000503:physiopathology*; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000503:physiopathology*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D058609:Visual Field Tests / Q000379:methods*; D014794:Visual Fields / Q000502:physiology*
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green