title: Implementation and evaluation of an Asbru-based decision support system for adjuvant treatment in breast cancer.
abstract: The domain of cancer treatment is a promising field for the implementation and evaluation of a protocol-based clinical decision support system, because of the algorithmic nature of treatment recommendations. However, many factors can limit such systems' potential to support the decision of clinicians: technical challenges related to the interoperability with existing electronic patient records and clinical challenges related to the inherent complexity of the decisions, often collectively taken by panels of different specialists. In this paper, we evaluate the performances of an Asbru-based decision support system implementing treatment protocols for breast cancer, which accesses data from an oncological electronic patient record. Focusing on the decision on the adjuvant pharmaceutical treatment for patients affected by early invasive breast cancer, we evaluate the matching of the system's recommendations with those issued by the multidisciplinary panel held weekly in a hospital.
authors: Fondazione Bruno Kessler, Trento, Italy. Electronic address: cleccher@fbk.eu.
authors: Claudio
authors: C
authors: Eccher
authors: Vienna University of Technology, Vienna, Austria.
authors: Andreas
authors: A
authors: Seyfang
authors: Medical Oncology, S. Chiara Hospital, Trento, Italy.
authors: Antonella
authors: A
authors: Ferro
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000188:drug therapy*; D017024:Chemotherapy, Adjuvant; D020000:Decision Support Systems, Clinical; D004360:Drug Therapy, Computer-Assisted / Q000379:methods*; D005260:Female; D006801:Humans; D011381:Programming Languages; D012984:Software
chemical_list: D000970:Antineoplastic Agents
keywords: Asbru; Clinical guidelines; Decision support systems