title: Predicting psychosis and psychiatric hospital care among adolescent psychiatric patients with the Prodromal Questionnaire.
abstract: The Prodromal Questionnaire (PQ) identifies psychiatric help-seekers in need of clinical interviews to diagnose psychosis risk. However, some providers use the PQ alone to identify risk. Therefore, we tested its predictive utility among 731 adolescent psychiatric help-seekers, with a 3-9-year register-based follow-up. Nine latent factors corresponded well with postulated subscales. Depersonalization predicted later hospitalization with a psychosis diagnosis (HR 1.6 per SD increase), and Role Functioning predicted any psychiatric hospitalization (HR 1.3). Published cut-off scores were poor predictors of psychosis; endorsement rates were very high for most symptoms. Therefore, we do not recommend using the PQ without second-stage clinical interviews.
authors: National Institute for Health and Welfare, Department of Mental Health and Substance Abuse Services, P.O. Box 30, FI-00271 Helsinki, Finland. Electronic address: Sebastian.Therman@thl.fi.
authors: Sebastian
authors: S
authors: Therman
authors: National Institute for Health and Welfare, Department of Mental Health and Substance Abuse Services, P.O. Box 30, FI-00271 Helsinki, Finland. Electronic address: Maija.Lindgren@thl.fi.
authors: Maija
authors: M
authors: Lindgren
authors: National Institute for Health and Welfare, Department of Mental Health and Substance Abuse Services, P.O. Box 30, FI-00271 Helsinki, Finland. Electronic address: Marko.Manninen@thl.fi.
authors: Marko
authors: M
authors: Manninen
authors: University of California, San Francisco, Department of Psychiatry, Box 0984 PAR, 401 Parnassus Ave., LangPorter, San Francisco, CA 94143, United States. Electronic address: RachelL@lppi.ucsf.edu.
authors: Rachel L
authors: RL
authors: Loewy
authors: National Institute for Health and Welfare, Department of Mental Health and Substance Abuse Services, P.O. Box 30, FI-00271 Helsinki, Finland. Electronic address: Matti.Huttunen@konsmoh.inet.fi.
authors: Matti O
authors: MO
authors: Huttunen
authors: Yale University, Department of Psychology, Box 208205, 2 Hillhouse Ave., New Haven, CT 06520-8205, United States. Electronic address: Tyrone.Cannon@yale.edu.
authors: Tyrone D
authors: TD
authors: Cannon
authors: National Institute for Health and Welfare, Department of Mental Health and Substance Abuse Services, P.O. Box 30, FI-00271 Helsinki, Finland. Electronic address: Jaana.Suvisaari@thl.fi.
authors: Jaana
authors: J
authors: Suvisaari
mesh_terms: D000293:Adolescent; D003861:Depersonalization; D005163:Factor Analysis, Statistical; D005260:Female; D005387:Finland; D005500:Follow-Up Studies; D006760:Hospitalization; D006801:Humans; D007406:Interview, Psychological / Q000379:methods; D008297:Male; D062706:Prodromal Symptoms; D011379:Prognosis; D016016:Proportional Hazards Models; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000523:psychology / Q000628:therapy; D012042:Registries; D012306:Risk; D057566:Self Report; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires; D016019:Survival Analysis
keywords: Adolescent; Follow-up; Psychosis prodrome; Screening; Self-report instrument