title: mPing: The bursting transposon.
abstract: Though transposable elements (TEs) have been considered as an efficient source of evolution, it has never been possible to test this hypothesis because most of TE insertions had occurred millions of years ago, or because currently active TEs have very few copies in a host genome. However, mPing, the first active DNA transposon in rice, was revealed to hold a key to answer this question. mPing has attained high copy numbers and still retained very high activity in a traditional rice strain, which enabled direct observation of behavior and impact of a bursting TE. A comprehensive analysis of mPing insertion sites has revealed it avoids exons but prefers promoter regions and thus moderately affects transcription of neighboring genes. Some of the mPing insertions have introduced possibly useful expression profile to adjacent genes that indicated TE's potential in de novo formation of gene regulatory network.
authors: Genetic Resource Center, National Institute of Agrobiological Sciences , 2-1-2 Kannondai, Tsukuba, Ibaraki 305-8602 , Japan.
authors: Ken
authors: K
authors: Naito
authors: Graduate School of Environmental and life Science, Okayama University , 3-1-1 Tsushima-naka, Kita, Okayama 700-8530 , Japan.
authors: Yuki
authors: Y
authors: Monden
authors: Department of Agriculture, Kyoto University , Kitashirakawa Oiwake, Sakyo, Kyoto 606-8502 , Japan.
authors: Kanako
authors: K
authors: Yasuda
authors: Department of Agriculture, Kyoto University , Kitashirakawa Oiwake, Sakyo, Kyoto 606-8502 , Japan.
authors: Hiroki
authors: H
authors: Saito
authors: Department of Agriculture, Kyoto University , Kitashirakawa Oiwake, Sakyo, Kyoto 606-8502 , Japan.
authors: Yutaka
authors: Y
authors: Okumoto
keywords: Oryza sativa; gene regulation; genome evolution; transposable element