title: Organocatalysed multicomponent synthesis of pyrazolidinones: Meldrum's acid approach.
abstract: We discovered a novel organocatalysed multicomponent domino Knoevenagel-aza-Michael-cyclocondensation reaction leading to an unprecedented straightforward synthesis of 1,5-diazabicyclo[3.3.0]octane-2,6-diones. The specific capability of the (DHQ)2PHAL organocatalyst in this process was also highlighted to eventually furnish the corresponding bicyclopyrazolidinones with up to 96 : 4 er.
authors: Normandie Univ, COBRA, UMR 6014 et FR 3038, Univ Rouen, INSA Rouen, CNRS, IRCOF, 1 rue Tesnière, 76821 Mont Saint Aignan cedex, France. jean-francois.briere@insa-rouen.fr.
authors: Etienne
authors: E
authors: Pair
authors: Christophe
authors: C
authors: Berini
authors: Romain
authors: R
authors: Noël
authors: Morgane
authors: M
authors: Sanselme
authors: Vincent
authors: V
authors: Levacher
authors: Jean-François
authors: JF
authors: Brière