title: Synthesis and characterization of gold nanotube/nanowire-polyurethane composite based on castor oil and polyethylene glycol.
abstract: Gold nanotubes/nanowires (GNT/NW) were synthesized by using the template-assisted electrodeposition technique and mixed with castor oil-polyethylene glycol based polyurethane (PU) to fabricate porous composite scaffolds for biomedical application. 100 and 50 ppm of GNT/NW were used to synthesize composites. The composite scaffolds were characterized by Fourier transform infrared spectroscopy, dynamic mechanical thermal analysis, differential scanning calorimetry, and scanning electron microscopy. Cell attachment on polyurethane-GNT/NW composites was investigated using fat-derived mesenchymal stem cells. Addition of 50 or 100 ppm GNT/NW had significant effects on thermal, mechanical, and cell attachment of polyurethane. Higher crosslink density and better cell attachment and proliferation were observed in polyurethane containing 50 ppm GNT/NW. The results revealed that GNT/NW formed hydrogen bonding with the polyurethane matrix and improved the thermomechanical properties of nanocomposites. Compared with pure PU, better cellular attachment on polyurethane-GNT/NW composites was observed resulting from the improved surface properties of composites.
authors: Faculty of Biomedical Engineering, Amirkabir University of Technology, 424 Hafez Ave., Tehran, Iran. Electronic address: y.ganji@aut.ac.ir.
authors: Yasaman
authors: Y
authors: Ganji
authors: Faculty of Biomedical Engineering, Amirkabir University of Technology, 424 Hafez Ave., Tehran, Iran. Electronic address: mkasra@aut.ac.ir.
authors: Mehran
authors: M
authors: Kasra
authors: Faculty of Biomedical Engineering, Amirkabir University of Technology, 424 Hafez Ave., Tehran, Iran. Electronic address: s.kordestani@aut.ac.ir.
authors: Soheila
authors: S
authors: Salahshour Kordestani
authors: Materials Science and Engineering Department, Sharif University of Technology, Azadi Ave., Tehran, Iran. Electronic address: mohibagheri@gmail.com.
authors: Mohiedin
authors: M
authors: Bagheri Hariri
mesh_terms: D000818:Animals; D002368:Castor Oil / Q000737:chemistry*; D002448:Cell Adhesion; D002478:Cells, Cultured; D006046:Gold / Q000737:chemistry*; D059630:Mesenchymal Stem Cells; D053761:Nanocomposites / Q000737:chemistry* / Q000648:ultrastructure; D043942:Nanotubes / Q000737:chemistry; D053770:Nanowires / Q000737:chemistry; D011092:Polyethylene Glycols / Q000737:chemistry*; D011140:Polyurethanes / Q000737:chemistry*; D016062:Porosity; D011817:Rabbits; D054457:Tissue Scaffolds / Q000737:chemistry
chemical_list: D011140:Polyurethanes; D011092:Polyethylene Glycols; D006046:Gold; D002368:Castor Oil
keywords: Castor oil; Gold nanotube/nanowire; Polyethylene glycol; Polyurethane; Scaffold