title: Physiology of iron metabolism.
abstract: A revolution occurred during the last decade in the comprehension of the physiology as well as in the physiopathology of iron metabolism. The purpose of this review is to summarize the recent knowledge that has accumulated, allowing a better comprehension of the mechanisms implicated in iron homeostasis. Iron metabolism is very fine tuned. The free molecule is very toxic; therefore, complex regulatory mechanisms have been developed in mammalian to insure adequate intestinal absorption, transportation, utilization, and elimination. 'Ironomics' certainly will be the future of the understanding of genes as well as of the protein-protein interactions involved in iron metabolism.
authors: Service régional vaudois de transfusion sanguine, Epalinges, Switzerland.
authors: Sophie
authors: S
authors: Waldvogel-Abramowski
authors: Service de médecine interne, CHUV, Lausanne, Switzerland.
authors: Gérard
authors: G
authors: Waeber
authors: Blutspende Zurich, Schlieren, Switzerland.
authors: Christoph
authors: C
authors: Gassner
authors: Blutspende Beiderbasel, Basel, Switzerland.
authors: Andreas
authors: A
authors: Buser
authors: Blutspende Zurich, Schlieren, Switzerland.
authors: Beat M
authors: BM
authors: Frey
authors: Department of Ambulatory Care and Community Medicine, Lausanne, Switzerland.
authors: Bernard
authors: B
authors: Favrat
authors: Service régional vaudois de transfusion sanguine, Epalinges, Switzerland.
authors: Jean-Daniel
authors: JD
authors: Tissot
keywords: Iron; Metabolism; Transfusion medicine