title: Oxetanyl peptides: novel peptidomimetic modules for medicinal chemistry.
abstract: The synthesis of novel oxetanyl peptides, where the amide bond is replaced by a non-hydrolyzable oxetanylamine fragment, is reported. This new class of pseudo-dipeptides with the same H-bond donor/acceptor pattern found in proteins expands the repertoire of peptidomimetics.
authors: Department of Chemistry and Applied Biosciences, Laboratorium für Organische Chemie, Vladimir-Prelog-Weg 3, Eidgenössische Technische Hochschule Zürich , CH-8093 Zürich, Switzerland.
authors: Martin
authors: M
authors: McLaughlin
authors: Ryo
authors: R
authors: Yazaki
authors: Thomas C
authors: TC
authors: Fessard
authors: Erick M
authors: EM
authors: Carreira
mesh_terms: D002626:Chemistry, Pharmaceutical; D004151:Dipeptides / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry*; D057786:Peptidomimetics; D011506:Proteins / Q000737:chemistry
chemical_list: D004151:Dipeptides; D010455:Peptides; D057786:Peptidomimetics; D011506:Proteins