title: Leaf-templated synthesis of 3D hierarchical porous cobalt oxide nanostructure as direct electrochemical biosensing interface with enhanced electrocatalysis.
abstract: A novel three-dimensional (3D) hierarchical porous cobalt oxide (Co3O4) architecture was first synthesized through a simple, cost-effective and environmentally friendly leaf-templated strategy. The Co3O4 nanoparticles (30-100 nm) with irregular shapes were interconnected with each other to form a 3D multilayer porous network structure, which provided high specific surface area and numerous electrocatalytic active sites. Subsequently, Co3O4 was successfully utilized as direct electrochemical sensing interface for non-enzymatic detection of H2O2 and glucose. By using chronoamperometry, the current response of the sensor at +0.31 V was linear with H2O2 concentration within 0.4-200 μM with a low limit of detection (LOD) of 0.24 μM (S/N=3) and a high sensitivity of 389.7 μA mM(-1) cm(-2). Two linear ranges of 1-300 μM (with LOD of 0.1 μM and sensitivity of 471.5 μA mM(-1) cm(-2)) and 4-12.5 mM were found at +0.59 V for glucose. In addition, the as-prepared sensor showed excellent stability and anti-interference performance for possible interferents such as ascorbic acid, uric acid, dopamine, acetaminophen and especially 0.15 M chloride ions. Similarly, other various metal oxide nanostructures may be also prepared using this similar strategy for possible applications in catalysis, electrochemical sensors, and fuel cells.
authors: Laboratory for Biosensing, Qingdao Institute of Bioenergy & Bioprocess Technology, and Key Laboratory of Biofuels, Chinese Academy of Sciences, 189 Songling Road, Qingdao 266101, China; University of Chinese Academy of Sciences, 19A Yuquan Road, Beijing 100049, China.
authors: Lei
authors: L
authors: Han
authors: Laboratory for Biosensing, Qingdao Institute of Bioenergy & Bioprocess Technology, and Key Laboratory of Biofuels, Chinese Academy of Sciences, 189 Songling Road, Qingdao 266101, China. Electronic address: yangdp@qibebt.ac.cn.
authors: Da-Peng
authors: DP
authors: Yang
authors: Laboratory for Biosensing, Qingdao Institute of Bioenergy & Bioprocess Technology, and Key Laboratory of Biofuels, Chinese Academy of Sciences, 189 Songling Road, Qingdao 266101, China; University of Chinese Academy of Sciences, 19A Yuquan Road, Beijing 100049, China. Electronic address: liuah@qibebt.ac.cn.
authors: Aihua
authors: A
authors: Liu
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation; D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D003217:Conductometry / Q000295:instrumentation*; D004566:Electrodes; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005947:Glucose / Q000032:analysis*; D006861:Hydrogen Peroxide / Q000032:analysis; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D054802:Molecular Imprinting / Q000379:methods*; D058608:Nanopores / Q000648:ultrastructure; D010087:Oxides / Q000737:chemistry*; D018515:Plant Leaves / Q000648:ultrastructure*; D016062:Porosity; D013499:Surface Properties
chemical_list: D010087:Oxides; D003035:Cobalt; D006861:Hydrogen Peroxide; D005947:Glucose; C060728:cobalt oxide
keywords: Biomimetic synthesis; Biomineralization; Hierarchical porous cobalt oxide architecture; Leaf template; Nonenzymatic glucose sensor