title: Resident rounds part III: plaque on left areola of an African-American woman.
abstract: Basal cell carcinoma (BCC) is the most common cutaneous malignancy, and usually presents on sun-exposed areas of the skin. Unsurprisingly, BCC appearing on the nipple-areola complex (NAC) is rare, and even more so in females and dark skin types. BCC of the NAC is more aggressive than other locations, thus diagnosis and treatment are imperative. We present a case of an African American female with a lichenified, scaly plaque on her left areola that was unresponsive to clobetasol. After biopsy, the lesion was identified as pigmented BCC of the NAC. The patient denied surgical treatment and was treated with topical 5-fluorouracil. The BCC initially resolved but recurred at 22 month follow-up. We plan to treat the recurrence with Mohs surgery.
authors: Lindsey
authors: L
authors: Goddard
authors: Todd
authors: T
authors: Mollet
authors: Travis
authors: T
authors: Blalock
mesh_terms: D000287:Administration, Topical; D001741:Black or African American; D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000627:therapeutic use; D001706:Biopsy; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D002280:Basal Cell Carcinoma / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D015580:Mohs Surgery / Q000379:methods; D009364:Neoplasm Recurrence, Local; D009558:Nipples / Q000473:pathology*; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy
chemical_list: D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil