title: Lipid profile in children with coronary artery disease in Sindh, Pakistan.
abstract: OBJECTIVE
  To evaluate lipid profile in children with coronary artery disease (CAD) in Hyderabad, Sindh, Pakistan.
  
  
  METHODS
  The study included 100 children (6-15 years), of which 43 were children of young parents (one or both) with recognized CAD, while the other 57 were children with no evidence of CAD (controls). All were evaluated for fasting blood lipid profile. Blood samples were collected from patients with CAD and healthy controls and analysis of the levels of lipid profile were carried out using a kit method on Microlab 300.
  
  
  RESULTS
  Children with CAD had significantly higher levels of total serum cholesterol and triglycerides and decreased levels of high density lipoprotein and low density lipoprotein compared to children in the control group. Systolic and diastolic blood pressures were significantly higher, without any significant difference.
  
  
  CONCLUSIONS
  CAD risk factors are significant regarding abnormal lipid levels. Genetic tendency seems to be important in the development of CAD in children.
authors: Saira Baloch, Bikha Ram Devrajani, Medical Research Center, Liaquat University of Medical and Health Sciences, Sindh 75000, Pakistan.
authors: Saira
authors: S
authors: Baloch
authors: Saira Baloch, Bikha Ram Devrajani, Medical Research Center, Liaquat University of Medical and Health Sciences, Sindh 75000, Pakistan.
authors: Bikha Ram
authors: BR
authors: Devrajani
authors: Saira Baloch, Bikha Ram Devrajani, Medical Research Center, Liaquat University of Medical and Health Sciences, Sindh 75000, Pakistan.
authors: Mohsin Ali
authors: MA
authors: Baloch
authors: Saira Baloch, Bikha Ram Devrajani, Medical Research Center, Liaquat University of Medical and Health Sciences, Sindh 75000, Pakistan.
authors: Mohammad Ali
authors: MA
authors: Pir
keywords: Children; Coronary artery disease; Lipid profile; Serum; Sindh