title: Middle lobe syndrome: a rare presentation of allergic bronchopulmonary aspergillosis.
abstract: Allergic bronchopulmonary aspergillosis (ABPA) is a disease predominantly seen in susceptible asthmatic subjects, due to a hypersensitivity phenomenon caused by colonisation of the airways by Aspergillus species. Although collapse, both lobar and segmental due to mucoid impaction, is not uncommon in ABPA, a middle lobe syndrome (MLS) secondary to ABPA is rather an uncommon association. We report this rare and unusual clinical presentation in a 36-year-old male, who presented for evaluation of a "non resolving pneumonia". Imaging suggested the presence of a MLS and central bronchiectasis. Further investigations revealed that the patient met 6/8 of the essential diagnostic criteria for ABPA. Appropriate therapy with oral corticosteroids resulted in remarkable symptomatic improvement.
authors: Department of Respiratory Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi 110 007, India. E-mail: ashokshah99@yahoo.com.
authors: A
authors: A
authors: Shah
authors: Department of Respiratory Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi 110 007, India.
authors: S
authors: S
authors: Behera
authors: Department of Respiratory Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi 110 007, India. Current affiliation: Department of Respiratory Medicine, Mata Chanan Devi Hospital, New Delhi, India.
authors: C
authors: C
authors: Panjabi
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008878:Middle Lobe Syndrome / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology
chemical_list: D000305:Adrenal Cortex Hormones
keywords: Allergic bronchopulmonary aspergillosis; Aspergillus; bronchial asthma; central bronchiectasis; middle lobe syndrome