title: Propofol as a panacea for acute kidney injury?
abstract: Yoo and colleagues report a small but provocative randomized clinical trial to prevent acute kidney injury in the setting of cardiopulmonary bypass surgery. Their article describes a trial of 112 patients undergoing valvular surgery with cardiopulmonary bypass who were randomized to receive sevoflurane (an inhaled anesthetic) or propofol for general anesthesia. The use of propofol was associated with a significant decrease in the rate of postoperative acute kidney injury.
authors: Department of Anesthesia, University of California, San Francisco, San Francisco, California, USA.
authors: Lindsey L
authors: LL
authors: Huddleston
authors: 1] Division of Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, California, USA [2] Division of Critical Care Medicine, Department of Anesthesia, University of California, San Francisco, San Francisco, California, USA.
authors: Kathleen D
authors: KD
authors: Liu
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology* / Q000517:prevention & control*; D018681:Anesthetics, General / Q000009:adverse effects* / Q000627:therapeutic use*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D005260:Female; D006349:Heart Valve Diseases / Q000601:surgery*; D006801:Humans; D008297:Male
chemical_list: D018681:Anesthetics, General