title: Uneventful benznidazole treatment of acute Chagas disease during pregnancy: a case report.
abstract: This report describes the case of a patient with acute Chagas disease in Tocantins, Brazil, who was unaware of her pregnancy during benznidazole treatment. She presented with impaired cardiac function during the acute phase (pericarditis and incomplete right bundle-branch block) that resolved favorably after benznidazole therapy. Serological results also became negative, as determined by hemagglutination assays, enzyme-linked immunosorbent assays, and immunofluorescence assays. The child was born without sequelae and showed no evidence of congenital Trypanosoma cruzi infection at birth or 24 days later.
authors: Faculdade de Medicina, Instituto Tocantinense Presidente Antonio Carlos, Araguaina, TO, Brasil.
authors: Valeria Rita
authors: VR
authors: Corrêa
authors: Faculdade de Medicina, Instituto Tocantinense Presidente Antonio Carlos, Araguaina, TO, Brasil.
authors: Fernanda Gama
authors: FG
authors: Barbosa
authors: Faculdade de Medicina, Instituto Tocantinense Presidente Antonio Carlos, Araguaina, TO, Brasil.
authors: Claudimar Américo de
authors: CA
authors: Melo Junior
authors: Faculdade de Medicina, Instituto Tocantinense Presidente Antonio Carlos, Araguaina, TO, Brasil.
authors: Luis Fernando
authors: LF
authors: D'Albuquerque e Castro
authors: Instituto de Medicina Tropical, Universidade de São Paulo, São Paulo, SP, Brazil.
authors: Heitor Franco de
authors: HF
authors: Andrade Junior
authors: Centro de Biotecnologia, Instituto de Pesquisas Energéticas e Nucleares, São Paulo, SP, Brazil.
authors: Nanci
authors: N
authors: Nascimento
mesh_terms: D000208:Acute Disease; D014355:Chagas Disease / Q000151:congenital / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009593:Nitroimidazoles / Q000627:therapeutic use*; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000188:drug therapy*; D014344:Trypanocidal Agents / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D009593:Nitroimidazoles; D014344:Trypanocidal Agents; C009999:benzonidazole