title: The Repurposing Drugs in Oncology (ReDO) Project.
abstract: The Repurposing Drugs in Oncology (ReDO) Project seeks to repurpose well-known and well-characterised non-cancer drugs for new uses in oncology. The rationale for this project is presented, examining current issues in oncological drug development, challenges for health systems, and existing and future patient needs. In addition to discussing the advantages of repurposing, the paper also outlines some of the characteristics used in the selection of drug candidates by this project. Challenges in moving candidate drugs into clinical trial and subsequent practice are also discussed.
authors: Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium ; The George Pantziarka TP53 Trust, London KT1 2JP, UK.
authors: Pan
authors: P
authors: Pantziarka
authors: Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.
authors: Gauthier
authors: G
authors: Bouche
authors: Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.
authors: Lydie
authors: L
authors: Meheus
authors: GlobalCures, Inc, Newton, MA 02459, USA.
authors: Vidula
authors: V
authors: Sukhatme
authors: GlobalCures, Inc, Newton, MA 02459, USA.
authors: Vikas P
authors: VP
authors: Sukhatme
authors: GlobalCures, Inc, Newton, MA 02459, USA ; Beth Israel Deaconess Medical Centre and Harvard Medical School, Boston, MA 02215, USA.
authors: P
authors: P
authors: Vikas
keywords: ReDO Project; drug development; drug repurposing; health economics; health policy; metronomics