title: From PET/CT to PET/MRI: advances in instrumentation and clinical applications.
abstract: Multimodality imaging of positron emission tomography/computed tomography (PET/CT) provides both metabolic information and the anatomic structure, which is significantly superior to either PET or CT alone and has greatly improved its clinical applications. Because of the higher soft-tissue contrast of magnetic resonance imaging (MRI) and no extra ionizing radiation, PET/MRI imaging is the hottest topic currently. PET/MRI is swiftly making its way into clinical practice. However, it has many technical difficulties to overcome, such as photomultiplier tubes, which cannot work properly in a magnetic field, and the inability to provide density information on the object for attenuation correction. This paper introduces the technique process of PET/MRI and summarizes its clinical applications, including imaging in oncology, neurology, and cardiology.
authors: Institute of Automation, Chinese Academy of Sciences , Beijing 100190, China.
authors: Zhenhua
authors: Z
authors: Hu
authors: Weidong
authors: W
authors: Yang
authors: Haixiao
authors: H
authors: Liu
authors: Kun
authors: K
authors: Wang
authors: Chengpeng
authors: C
authors: Bao
authors: Tianming
authors: T
authors: Song
authors: Jing
authors: J
authors: Wang
authors: Jie
authors: J
authors: Tian
mesh_terms: D000818:Animals; D004867:Equipment Design; D006801:Humans; D060526:Magnetic Fields; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008495:Medical Oncology / Q000379:methods; D064847:Multimodal Imaging / Q000379:methods; D009369:Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D049268:Positron-Emission Tomography / Q000379:methods*; D011839:Radiation, Ionizing; D014057:Tomography, X-Ray Computed / Q000379:methods*
keywords: attenuation correction; cardiology; neurologic disease; oncology; positron emission tomography/computed tomography (PET/CT); positron emission tomography/magnetic resonance imaging (PET/MRI); silicon photomultiplier (SiPM); time-of-flight (TOF)