title: Possible Tyromyces fissilis (Basidiomycota, Polyporales) co-infection in a lung transplant recipient.
abstract: Invasive fungal diseases are severe complication of the lung transplant patients' follow-up as they are increasing the risk of rejection. We report a patient who developed possible Tyromyces fissilis co-infection during graft rejection episode 2 years after bilateral lung transplantation for cystic fibrosis. The fungus was detected using conventional culture methods as a filamentous basidiomycete and further placed to T. fissilis species based on internal transcribed spacer (ITS) rDNA sequences. The patient was treated according to the susceptibility testing results by voriconazole in combination with the anti-rejection therapy and recovered completely within few weeks. This is, to our knowledge, the first published case report of T. fissilis as a possible causative agent of an infection/rejection episode in a lung transplant recipient.
authors: Department of Medical Microbiology 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, V Uvalu 84, 15006, Prague 5, Czech Republic, vanda.chrenkova@fnmotol.cz.
authors: Vanda
authors: V
authors: Chrenkova
authors: Miroslav
authors: M
authors: Kolarik
authors: Petr
authors: P
authors: Hubacek
authors: Jan
authors: J
authors: Kolarik
authors: Jan
authors: J
authors: Simonek
authors: Robert
authors: R
authors: Lischke
authors: Pavel
authors: P
authors: Drevinek
mesh_terms: D000328:Adult; D006084:Graft Rejection / Q000382:microbiology*; D006801:Humans; D016040:Lung Transplantation / Q000009:adverse effects*; D008297:Male; D009181:Mycoses / Q000209:etiology / Q000382:microbiology*; D020072:Polyporales / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology*; D011183:Postoperative Complications / Q000209:etiology / Q000382:microbiology*; D066027:Transplant Recipients; D055815:Young Adult