title: Clinical analysis of secondary acquired cholesteatoma.
abstract: OBJECTIVE
  This study aimed to analyze the clinical features of patients who underwent surgery for secondary acquired cholesteatoma (SAC).
  
  
  METHODS
  The subjects were 30 patients who underwent surgery for SAC in 30 ears. We investigated the age distribution, sex, tympanic membrane (TM) findings, temporal bone pneumatization, morphology of TM epidermis invasion, extent of cholesteatoma invasion, ossicular erosion, surgical methods and surgical results.
  
  
  RESULTS
  There were 10 males (33.3%) and 20 females (66.6%), with a mean age 54.9 years. The TM perforation was medium-sized or larger in 27 ears (90%). Temporal bone pneumatization was poor or bad in 90% (18/20) of the evaluated ears. The cholesteatoma invaded from the malleus manubrium to the promontory in 23 ears (76.7%). There were no patients in whom the cholesteatoma invaded the antrum or mastoid. The ossicles were affected in 19 ears (63.3%). Ossiculoplasty with a columella on the stapes was the most frequent procedure, performed for 16 ears (53.3%). There were no hearing results with a postoperative air-bone gap of more than 31 dB.
  
  
  CONCLUSIONS
  Although SAC is rare, it is important for the clinician to keep this type of cholesteatoma in mind.
authors: Department of Otorhinolaryngology, Jikei University School of Medicine, Tokyo, Japan. Electronic address: kazu1109@jikei.ac.jp.
authors: Kazuhisa
authors: K
authors: Yamamoto
authors: Department of Otorhinolaryngology, Jikei University School of Medicine, Tokyo, Japan.
authors: Yuichiro
authors: Y
authors: Yaguchi
authors: Department of Otorhinolaryngology, Jikei University School of Medicine, Tokyo, Japan.
authors: Hiromi
authors: H
authors: Kojima
mesh_terms: D000328:Adult; D000368:Aged; D018424:Cholesteatoma, Middle Ear / Q000473:pathology* / Q000601:surgery*; D004429:Ear Ossicles / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D013701:Temporal Bone / Q000473:pathology; D016896:Treatment Outcome; D018058:Tympanic Membrane Perforation / Q000473:pathology