title: Frontal ostium neo-osteogenesis and patency after Draf III procedure: a computer-assisted study.
abstract: BACKGROUND
  Stenosis of the frontal neo-ostium after Draf III procedure has been associated with inflammatory risk factors. However, the degree to which neo-osteogenesis contributes to postsurgical stenosis of the frontal neo-ostium is unclear.
  
  
  METHODS
  Twenty-five patients with chronic frontal sinusitis who underwent Draf III procedure and had been followed for at least 12 months were included. Paranasal sinus computed tomography (CT) scans were performed 7 days and 1 year postoperatively. The frontal neo-ostium cross-sectional area and the amount of frontal neo-osteogenesis were measured by a standardized protocol using triplanar radiologic viewing software. Association between the severity of frontal neo-osteogenesis and the patency of the neo-ostium was analyzed, as was the correlation between the extent of neo-osteogenesis and the preoperative Global Osteitis Scoring Scale (GOSS), Lund-Mackay score (LMS), Lund-Kennedy score (LKS), serum eosinophil count, and history of previous surgery.
  
  
  RESULTS
  At 1 year postoperatively, significant inverse correlation was found between the size of the frontal neo-ostium and the extent of neo-osteogenesis. According to a multiple linear regression model, the severity of neo-osteogenesis was positively correlated with preoperative GOSS and negatively correlated with asthma (p < 0.05). Additionally, there was no association between extent of neo-osteogenesis and the preoperative LMS, LKS, serum eosinophil count, and history of previous surgery.
  
  
  CONCLUSIONS
  Neo-osteogenesis has a significant impact on the patency of the frontal neo-ostium but appears unrelated to inflammatory factors. Patients with a higher risk for developing neo-osteogenesis can be identified preoperatively based on GOSS; these patients may benefit from closer monitoring during the follow-up period.
authors: Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing.
authors: Ting
authors: T
authors: Ye
authors: Peter H
authors: PH
authors: Hwang
authors: Zhenxiao
authors: Z
authors: Huang
authors: Qian
authors: Q
authors: Huang
authors: Junfang
authors: J
authors: Xian
authors: Cheng
authors: C
authors: Li
authors: Bing
authors: B
authors: Zhou
mesh_terms: D000328:Adult; D002908:Chronic Disease; D004724:Endoscopy; D005260:Female; D005626:Frontal Sinus / Q000000981:diagnostic imaging* / Q000601:surgery*; D015522:Frontal Sinusitis / Q000000981:diagnostic imaging* / Q000601:surgery*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D010012:Osteogenesis; D012220:Rhinitis / Q000000981:diagnostic imaging / Q000601:surgery; D012984:Software; D014057:Tomography, X-Ray Computed
keywords: Draf III procedure; chronic rhinosinusitis; computed tomography; neo-osteogenesis; patency