title: Meta-analysis of the risk of cataract in type 2 diabetes.
abstract: BACKGROUND
  This meta-analysis aimed to investigate the association between type 2 diabetes (T2D) and the risk of cataract.
  
  
  METHODS
  Databases of Pubmed, Embase, and SpringerLink were retrieved for observational studies published before November 2013. The odds ratio (OR) and 95% confidence interval (CI) were used for estimating the association. All statistical analyses were performed by Stata 10.0 software.
  
  
  RESULTS
  A total of 8 studies involving 20837 subjects were included in the meta-analysis. The risk of any cataract (AC) in T2D patients was higher than that in non-diabetic subjects (OR = 1.97, 95% CI: 1.45-2.67, P < 0.001). The risks of cortical cataract posterior (CC) (OR = 1.68, 95% CI: 1.47-1.91, P < 0.001) and posterior subcapsular (PSC) (OR = 1.55, 95% CI: 1.27-1.90, P < 0.001) were significantly elevated in T2D patients, while no significant association was found in nuclear sclerosis (NS) (OR = 1.36, 95% CI: 0.97-1.90, P = 0.070).
  
  
  CONCLUSIONS
  T2D patients had a higher risk of cataracts, excepting NS. Special attention should be paid on the ophthalmic extermination, especially for cataract in T2D patients.
authors: Department of Ophthalmology, The Affiliated Beijing Children's Hospital of Capital Medical University; National Key Discipline of Pediatrics, Ministry of Education, Beijing 100045, China. lliilili2@hotmail.com.
authors: Li
authors: L
authors: Li
authors: Xiu-hua
authors: XH
authors: Wan
authors: Guo-hong
authors: GH
authors: Zhao
mesh_terms: D000375:Aging; D002386:Cataract / Q000453:epidemiology / Q000209:etiology*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000453:epidemiology; D014943:Global Health; D006801:Humans; D015994:Incidence; D016017:Odds Ratio; D015995:Prevalence; D018570:Risk Assessment; D012307:Risk Factors