title: Effects of material, coating, design and plaque composition on stent deployment inside a stenotic artery--finite element simulation.
abstract: Finite-element simulations have been carried out to study the effects of material choice, drug eluting coating and cell design on the mechanical behaviour of stents during deployment inside a stenotic artery. Metallic stents made of materials with lower yield stress and weaker strain hardening tend to experience higher deformation and stronger dogboning and recoiling, but less residual stresses. Drug eluting coatings have limited effect on stent expansion, recoiling, dogboning and residual stresses. Stent expansion is mainly controlled by the radial stiffness of the stent which is closely associated with the stent design. In particular, open-cell design tends to have easier expansion and higher recoiling than closed-cell design. Dogboning is stronger for slotted tube design and open-cell sinusoidal design, but reduced significantly for designs strengthened with longitudinal connective struts. After deployment, the maximum von Mises stress appears to locate at the U-bends of stent cell struts, with varying magnitude that depends on the materials and severity of plastic deformation. For the artery-plaque system, the stresses, especially in the plaque which is in direct contact with the stent, appear to be distinctly different for different stent designs and materials in terms of both distribution and magnitude. The plaque composition also strongly affects the expansion behaviour of the stent-artery system and modifies the stresses on the plaque.
authors: Wolfson School of Mechanical and Manufacturing Engineering, Loughborough University, LE11 3TU Loughborough, UK.
authors: A
authors: A
authors: Schiavone
authors: Wolfson School of Mechanical and Manufacturing Engineering, Loughborough University, LE11 3TU Loughborough, UK. Electronic address: L.Zhao@Lboro.ac.uk.
authors: L G
authors: LG
authors: Zhao
authors: Wolfson School of Mechanical and Manufacturing Engineering, Loughborough University, LE11 3TU Loughborough, UK.
authors: A A
authors: AA
authors: Abdel-Wahab
mesh_terms: D001157:Arterial Occlusive Diseases / Q000473:pathology; D003198:Computer Simulation; D054855:Drug-Eluting Stents; D020342:Finite Element Analysis; D006801:Humans; D008422:Materials Testing / Q000379:methods*; D008955:Models, Cardiovascular; D058226:Plaque, Atherosclerotic / Q000473:pathology*; D011474:Prosthesis Design / Q000379:methods*
keywords: Dogboning; Finite element; Recoiling; Stenotic artery; Stent expansion; Stresses