title: Cardiac biomarkers for infarct diagnosis and early exclusion of acute coronary syndrome.
abstract: The acute coronary syndrome (ACS) represents a diagnostic challenge: on the one hand patients need to be quickly identified to initiate treatment and on the other hand early exclusion of patients without ACS is important to relieve patient stress as well as overcrowded emergency departments. A growing number of biomarkers are becoming available to aid physicians with this task. This review gives an overview of the current research concerning early exclusion with an emphasis on the clinically most important biomarker: cardiac troponin.
authors: Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.
authors: C
authors: C
authors: Puelacher
authors: P
authors: P
authors: Hillinger
authors: M
authors: M
authors: Wagener
authors: C
authors: C
authors: Müller
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood* / Q000175:diagnosis*; D015415:Biomarkers / Q000097:blood; D055318:Evidence-Based Nursing; D000074026:Fatty Acid Binding Protein 3; D050556:Fatty Acid-Binding Proteins / Q000097:blood*; D006020:Glycopeptides / Q000097:blood*; D006801:Humans; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D019210:Troponin I / Q000097:blood*; D020107:Troponin T / Q000097:blood*
chemical_list: D015415:Biomarkers; C493408:FABP3 protein, human; D000074026:Fatty Acid Binding Protein 3; D050556:Fatty Acid-Binding Proteins; D006020:Glycopeptides; D019210:Troponin I; D020107:Troponin T; C048197:copeptins