title: Chronic mucocutaneous candidiasis: a case with exuberant cutaneous horns in nipples.
abstract: Chronic mucocutaneous candidiasis is a rare disorder characterized by persistent and recurrent infections by Candida due to changes in cellular immunity and may be associated with autoimmune endocrine disorders. It is refractory to the usual antifungal treatments, which merely control it with imidazole derivatives. This reports the case of a 50-year-old female patient who referred vaginal discharge associated with vulvar ulcerated lesions and whitish plaques on oral and genital mucous membranes of onset in adolescence besides cutaneous horns in nipples. The clinical picture, family history, culture and anatomopathological studies were consistent with chronic infection by candida. Treatment with systemic antifungals obtained partial response of lesions characterizing a clinical picture of Chronic Mucocutaneous Candidiasis.
authors: Santa Casa de Misericórdia de Vitória, Vitória, ES, Brazil.
authors: Antônio
authors: A
authors: Chambô Filho
authors: Santa Casa de Misericórdia de Vitória, Vitória, ES, Brazil.
authors: João Basilio de
authors: JB
authors: Souza Filho
authors: Santa Casa de Misericórdia de Vitória, Vitória, ES, Brazil.
authors: Christine Chambô
authors: CC
authors: Pignaton
authors: Santa Casa de Misericórdia de Vitória, Vitória, ES, Brazil.
authors: Ingrid
authors: I
authors: Zon
authors: Santa Casa de Misericórdia de Vitória, Vitória, ES, Brazil.
authors: Alan Santos
authors: AS
authors: Fernandes
authors: Santa Casa de Misericórdia de Vitória, Vitória, ES, Brazil.
authors: Lia Quintaes
authors: LQ
authors: Cardoso
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D001706:Biopsy; D002178:Candidiasis, Chronic Mucocutaneous / Q000188:drug therapy / Q000473:pathology*; D002180:Candidiasis, Oral / Q000188:drug therapy / Q000473:pathology; D002181:Candidiasis, Vulvovaginal / Q000188:drug therapy / Q000473:pathology; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D009558:Nipples / Q000473:pathology*; D012867:Skin / Q000473:pathology*; D014059:Tongue / Q000473:pathology; D016896:Treatment Outcome; D014844:Vulva / Q000473:pathology
chemical_list: D000935:Antifungal Agents; D015725:Fluconazole