title: Systems biology brings new dimensions for structure-based drug design.
abstract: In this Perspective, we focus on new, systems-centric views of structure-based drug design (SBDD) that we believe will impact future drug discovery research and development. We will first discuss new ways to identify drug targets based on systems intervention analysis, and then we will introduce emerging SBDD methods driven by advancements in systems biology.
authors: Center for Quantitative Biology, Academy for Advanced Interdisciplinary Studies, Peking University , Beijing 100871, China.
authors: Jianfeng
authors: J
authors: Pei
authors: Ning
authors: N
authors: Yin
authors: Xiaomin
authors: X
authors: Ma
authors: Luhua
authors: L
authors: Lai
mesh_terms: D015195:Drug Design; D006801:Humans; D015394:Molecular Structure; D049490:Systems Biology