title: Highly efficient anti-cancer therapy using scorpion 'NanoVenin'.
abstract: Host defence peptidotoxins from animal venoms have been identified to possess substantial anticancer properties. Towards a safer, translatable approach, we have developed a viable chemical methodology based on a well-defined, self-assembled polymeric nano-architecture for controlled delivery of toxins derived from scorpion venom.
authors: Department of Bioengineering and Beckman Institute, University of Illinois at Urbana-Champaign, 502 N. Busey, Urbana, IL 61801, USA. dipanjan@illinois.edu.
authors: Santosh K
authors: SK
authors: Misra
authors: Mao
authors: M
authors: Ye
authors: Sumin
authors: S
authors: Kim
authors: Dipanjan
authors: D
authors: Pan
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology*; D045744:Cell Line, Tumor; D004305:Dose-Response Relationship, Drug; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D061986:MCF-7 Cells; D008958:Models, Molecular; D015394:Molecular Structure; D049329:Nanostructures / Q000737:chemistry*; D010316:Particle Size; D012604:Scorpion Venoms / Q000737:chemistry* / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D013499:Surface Properties
chemical_list: D000970:Antineoplastic Agents; D012604:Scorpion Venoms