title: 3D printed high-throughput hydrothermal reactionware for discovery, optimization, and scale-up.
abstract: 3D printing techniques allow the laboratory-scale design and production of reactionware tailored to specific experimental requirements. To increase the range and versatility of reactionware devices, sealed, monolithic reactors suitable for use in hydrothermal synthesis have been digitally designed and realized. The fabrication process allows the introduction of reaction mixtures directly into the reactors during the production, and also enables the manufacture of devices of varying scales and geometries unavailable in traditional equipment. The utility of these devices is shown by the use of 3D printed, high-throughput array reactors to discover two new coordination polymers, optimize the synthesis of one of these, and scale-up its synthesis using larger reactors produced on the same 3D printer. Reactors were also used to produce phase-pure samples of coordination polymers MIL-96 and HKUST-1, in yields comparable to synthesis in traditional apparatus.
authors: WestCHEM, School of Chemistry, University of Glasgow, Glasgow G12 8QQ, Scotland (UK) http://www.croninlab.com.
authors: Philip J
authors: PJ
authors: Kitson
authors: Ross J
authors: RJ
authors: Marshall
authors: Deliang
authors: D
authors: Long
authors: Ross S
authors: RS
authors: Forgan
authors: Leroy
authors: L
authors: Cronin
keywords: 3D printing; coordination polymers; high-throughput synthesis; hydrothermal synthesis; reactor design