title: Concentrated ascites re-infusion therapy for pseudo-Meigs' syndrome complicated by massive ascites in large pedunculated uterine leiomyoma.
abstract: Pseudo-Meigs' syndrome accompanied by massive ascites in uterine leiomyoma is rare. We encountered a rare case of a 37-year-old, nulliparous woman with a lower abdominal tumor and severe abdominal distention due to massive ascites. Serum cancer antigen 125 and vascular endothelial growth factor levels were elevated to 1007.9 U/mL and 103 pg/mL, respectively. She was tentatively diagnosed with ovarian cancer. Emergency concentrated ascites re-infusion therapy was performed to improve dyspnea, abdominal pain, and her preoperative respiratory condition. Concentrated ascites re-infusion therapy eliminated dyspnea and abdominal discomfort without decreasing serum albumin levels. The patient underwent laparotomy, which revealed a fist-sized pedunculated uterine leiomyoma arising from the right uterine fundus. Myomectomy was performed. Pseudo-Meigs' syndrome mimics advanced ovarian cancer due to massive ascites and markedly elevated serum cancer antigen 125 and vascular endothelial growth factor levels. Concentrated ascites re-infusion therapy was effective in improving the subjective symptoms of pseudo-Meigs' syndrome and the patient's preoperative condition.
authors: Department of Obstetrics and Gynecology, Imamura Hospital, Kagoshima, Japan.
authors: Yukie
authors: Y
authors: Yonehara
authors: Shintaro
authors: S
authors: Yanazume
authors: Masaki
authors: M
authors: Kamio
authors: Shinichi
authors: S
authors: Togami
authors: Takashi
authors: T
authors: Tasaki
authors: Tsutomu
authors: T
authors: Douchi
mesh_terms: D000328:Adult; D001201:Ascites / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D001202:Ascitic Fluid; D003937:Diagnosis, Differential; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D007263:Infusions, Parenteral; D007564:Japan; D007889:Leiomyoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D008539:Meigs Syndrome / Q000175:diagnosis; D020360:Neoadjuvant Therapy; D010996:Pleural Effusion / Q000175:diagnosis / Q000503:physiopathology; D012720:Severity of Illness Index; D013577:Syndrome; D035703:Therapies, Investigational; D016896:Treatment Outcome; D047368:Tumor Burden; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*
keywords: concentrated ascites re-infusion therapy; massive ascites; pedunculated uterine leiomyoma; pseudo-Meigs' syndrome