title: Recording frequency-following responses to voice pitch in guinea pigs: preliminary results.
abstract: Although scalp-recorded frequency-following response (FFR) to voice pitch has shown great potential to examine pitch processing mechanisms in human participants and animals, few reports have addressed the test-retest reliability of such a response in an animal model. The purpose of this study was to investigate the feasibility and reliability of recording such a response in an animal model and to evaluate the extent to which the response could be separated from background noise. A Chinese monosyllable with a rising pitch was used to elicit the FFR to voice pitch in four guinea pigs. Four objective measures (Root-Mean-Square, Amplitude, Tracking Accuracy, Frequency Error, and Slope Error) were computed from recorded brain waves and were used to examine the phase-locking magnitude and test-retest reliability of the response. Results demonstrated that the animal model produced FFR trends that were repeatable, reliable, and significantly different from responses to the background noise.
authors: 1 Department of Otolaryngology-HNS, China Medical University Hospital, Taiwan.
authors: Meng-Shih
authors: MS
authors: Chou
authors: Chia-Der
authors: CD
authors: Lin
authors: Tang-Chuan
authors: TC
authors: Wang
authors: Fuh-Cherng
authors: FC
authors: Jeng
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology*; D004569:Electroencephalography; D005240:Feasibility Studies; D005260:Female; D006168:Guinea Pigs / Q000502:physiology*; D008297:Male; D009483:Neuropsychological Tests / Q000592:standards*; D010865:Pilot Projects; D010898:Pitch Perception / Q000502:physiology*; D015203:Reproducibility of Results