title: Molecular imprinted polymer-coated optical fiber sensor for the identification of low molecular weight molecules.
abstract: A biomimetic optical probe for detecting low molecular weight molecules (maltol, 3-hydroxy-2-methyl-4H-pyran-4-one, molecular weight of 126.11 g/mol), was designed, fabricated, and characterized. The sensor couples a molecular imprinted polymer (MIP) and the Bragg grating refractometry technology into an optical fiber. The probe is fabricated first by inscribing tilted grating planes in the core of the fiber, and then by photopolymerization to immobilize a maltol imprinted MIP on the fiber cladding surface over the Bragg grating. The sensor response to the presence of maltol in different media is obtained by spectral interrogation of the fiber transmission signal. The results showed that the limit of detection of the sensor reached 1 ng/mL in pure water with a sensitivity of 6.3 × 10(8)pm/M. The selectivity of the sensor against other compounds and its reusability were also studied experimentally. Finally, the unambiguous detection of concentrations as little as 10nM of maltol in complex media (real food samples) by the MIP-coated tilted fiber Bragg grating sensor was demonstrated.
authors: Department of Electronic, Carleton University, 1125 Colonel By Drive, Ottawa, ON, Canada K1S 5B6; Department of Chemistry, Carleton University, 1125 Colonel By Drive, Ottawa, ON, Canada K1S 5B6. Electronic address: slepinay@connect.carleton.ca.
authors: Sandrine
authors: S
authors: Lépinay
authors: Department of Chemistry, Carleton University, 1125 Colonel By Drive, Ottawa, ON, Canada K1S 5B6.
authors: Anatoli
authors: A
authors: Ianoul
authors: Department of Electronic, Carleton University, 1125 Colonel By Drive, Ottawa, ON, Canada K1S 5B6.
authors: Jacques
authors: J
authors: Albert
mesh_terms: D005336:Fiber Optic Technology / Q000295:instrumentation / Q000379:methods*; D005638:Fruit / Q000737:chemistry; D005782:Gels / Q000032:analysis / Q000737:chemistry; D018625:Microscopy, Atomic Force; D054802:Molecular Imprinting; D015394:Molecular Structure; D008970:Molecular Weight; D055100:Optical Fibers; D011108:Polymers / Q000737:chemistry*; D011753:Pyrones / Q000032:analysis* / Q000737:chemistry; D012031:Refractometry / Q000295:instrumentation / Q000379:methods*; D015203:Reproducibility of Results
chemical_list: D005782:Gels; D011108:Polymers; D011753:Pyrones; C008316:maltol
keywords: Chemical probe; Maltol; Molecular imprinted polymer; Tilted fiber Bragg grating