title: Diversity-oriented syntheses: coupling reactions between electron-deficient olefins and aryl aldehydes via C(sp2)-H functionalization.
abstract: A diversity-oriented syntheses by coupling three electron-deficient olefins (vinyl sulfonamides, methacrylamides, and methyl acrylates, respectively) with aryl aldehydes via C(sp(2))-H functionalization were reported. These reactions gave four different skeletal products respectively under environment-friendly and mild conditions. All these reactions are highly regioselective and effective, very suitable for the preparation of synthetic building blocks and compound library, the results will enrich current coupling chemistry of olefins with aldehydes and can be applied to other chemistry areas as well.
authors: Pharmacy School, Jiangsu University , Xuefu Road 301, Zhenjiang, Jiangsu, China , 212013.
authors: Ben
authors: B
authors: Niu
authors: Lei
authors: L
authors: Xu
authors: Ping
authors: P
authors: Xie
authors: Min
authors: M
authors: Wang
authors: Wannian
authors: W
authors: Zhao
authors: Charles U
authors: CU
authors: Pittman
authors: Aihua
authors: A
authors: Zhou
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry*; D004583:Electrons; D015394:Molecular Structure
chemical_list: D000447:Aldehydes; D000475:Alkenes
keywords: C(sp2)−H functionalization; aldehydes; diversity-oriented synthesis; environmentally friendly; olefin; regioselective