title: Two new sesquiterpenoids from endophytic fungus J3 isolated from Mangrove Plant Ceriops tagal.
abstract: Two new sesquiterpenoids, named 2α-hydroxyxylaranol B (1) and 4β-hydroxyxylaranol B (2), together with a known diterpenoid 3,4-seco-sonderianol (3) were isolated from the fermentation of endophytic fungus J3 of Ceriops tagal. Their structures were elucidated based on spectroscopic methods including 1D and 2D NMR (HMQC, (1)H-(1)H COSY and HMBC). All compounds were evaluated for their cytotoxic activities by MTT method, and compound 3 exhibited cytotoxic activities against K562, SGC-7901, and BEL-7402 cell lines.
authors: Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, China.
authors: Yan-Bo
authors: YB
authors: Zeng
authors: Hai-Gang
authors: HG
authors: Gu
authors: Wen-Jian
authors: WJ
authors: Zuo
authors: Li-Li
authors: LL
authors: Zhang
authors: Hong-Jin
authors: HJ
authors: Bai
authors: Zhi-Kai
authors: ZK
authors: Guo
authors: Peter
authors: P
authors: Proksch
authors: Wen-Li
authors: WL
authors: Mei
authors: Hao-Fu
authors: HF
authors: Dai
mesh_terms: D003603:Cytotoxins / Q000737:chemistry / Q000302:isolation & purification; D060026:Endophytes / Q000302:isolation & purification*; D005658:Fungi / Q000302:isolation & purification*; D006801:Humans; D020014:K562 Cells; D018515:Plant Leaves; D043982:Rhizophoraceae; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification*
chemical_list: D003603:Cytotoxins; D012717:Sesquiterpenes