title: Simultaneous determination of 50 residual pesticides in Flos Chrysanthemi using accelerated solvent extraction and gas chromatography.
abstract: A gas chromatographic method for simultaneous determination of 50 organochlorine (OCP) and pyrethroid (PP) pesticides in Flos Chrysanthemi was established. Accelerated solvent extraction (ASE) technique was used to extract the target compounds, cleaned with alumina neutral-florisil column, and eluted by mixed solvents of ethyl acetate and hexane (15:85, v/v). Selected pesticides were identified using HP-5 and DB1701 capillary dual column and detected by electron-capture detector. Quantitative analysis was performed using an external standard by HP-5 capillary column. Results showed that recoveries were 73.4-120.1%, and the relative standard deviations (RSDs) were 1.6-12.4%. The limits of detection of the method were 0.0021-0.0069 mg/kg, and the limits of quantity were 0.0064-0.0210 mg/kg.
authors: Department of Pharmacy, Xinhua Hospital, Shanghai Jiao tong University School of Medicine, Shanghai 200092, China.
authors: Xiaohui
authors: X
authors: Huang
authors: Department of Pharmacy, Xuzhou Children's Hospital, Xuzhou 221000, China.
authors: Xinghui
authors: X
authors: Zhao
authors: Department of Pharmacy, Xinhua Hospital, Shanghai Jiao tong University School of Medicine, Shanghai 200092, China.
authors: Xiaotong
authors: X
authors: Lu
authors: Department of Pharmacy, Xinhua Hospital, Shanghai Jiao tong University School of Medicine, Shanghai 200092, China.
authors: Huaiping
authors: H
authors: Tian
authors: Department of Pharmacy, Xinhua Hospital, Shanghai Jiao tong University School of Medicine, Shanghai 200092, China.
authors: Ajing
authors: A
authors: Xu
authors: Department of Pharmacy, Xinhua Hospital, Shanghai Jiao tong University School of Medicine, Shanghai 200092, China.
authors: Yan
authors: Y
authors: Liu
authors: Department of Pharmacy, Xinhua Hospital, Shanghai Jiao tong University School of Medicine, Shanghai 200092, China. Electronic address: zj_boss@126.com.
authors: Zhang
authors: Z
authors: Jian
mesh_terms: D002849:Chromatography, Gas / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D006843:Hydrocarbons, Chlorinated / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D057230:Limit of Detection; D016014:Linear Models; D010573:Pesticide Residues / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification; D011722:Pyrethrins / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D015203:Reproducibility of Results; D052616:Solid Phase Extraction
chemical_list: D004365:Drugs, Chinese Herbal; D006843:Hydrocarbons, Chlorinated; D010573:Pesticide Residues; D011722:Pyrethrins
keywords: Flos Chrysanthemi; Gas chromatography; Multi-residues; Organochlorine pesticides (OCP); Pyrethroid pesticides (PP)