title: Oral rehydration with 10% carbohydrate drink for preventing postoperative nausea and vomiting (PONV) after low dose of spinal morphine.
abstract: BACKGROUND
  Preoperative oral carbohydrate (CHO) drink may improve patients' comfort. However, whether it prevents or reduces postoperative nausea and vomiting (PONV) is questionable.
  
  
  OBJECTIVE
  Evaluate the effect of oral rehydration with 10% CHO drink before anesthesia on incidence and severity of postoperative nausea and vomiting (PONV) after spinal morphine injection.
  
  
  METHODS
  One hundred patients scheduled for unilateral total knee replacement (TKR) were randomly divided into two equal groups (n = 50 each). Group I patients received 400 ml 10% CHO drink the preoperative night and 2-hour before anesthesia, whereas Group II patients served as control. Spinal anesthesia for all patients contained 0.5% bupivacaine 2.0 to 3.5 ml plus morphine 0.2 mg. Pain therapy was standardized with femoral nerve block, local infiltration, intravenous parecoxib, and oral paracetamol. Incidence and severity of PONV within 24 hours were recorded In addition, preoperative intensity of thirst and hunger, dry lips and throat, and anxiety was also recorded
  
  
  RESULTS
  Incidence and severity of PONV (81.2% vs. 72.0%, p = 0.536) as well as preoperative thirst, hunger dry lips, and throat were not different between the groups.
  
  
  CONCLUSIONS
  Preoperative oral rehydration with carbohydrate drinks had no positive effect on PONV nor patients' comfort.
authors: Manee
authors: M
authors: Raksakietisak
authors: Tithima
authors: T
authors: Chinachoti
authors: Arissara
authors: A
authors: Iamaroon
authors: Yos
authors: Y
authors: Thabpenthai
authors: Pathom
authors: P
authors: Halilamien
authors: Sasiya
authors: S
authors: Siriratwarangkul
authors: Arraya
authors: A
authors: Watanitanon
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000701:Analgesics, Opioid / Q000008:administration & dosage*; D000932:Antiemetics / Q000008:administration & dosage*; D001628:Beverages; D004040:Dietary Carbohydrates / Q000008:administration & dosage*; D005260:Female; D005440:Fluid Therapy / Q000379:methods*; D006801:Humans; D007278:Injections, Spinal; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage*; D020250:Postoperative Nausea and Vomiting / Q000517:prevention & control*; D011446:Prospective Studies; D016896:Treatment Outcome
chemical_list: D000701:Analgesics, Opioid; D000932:Antiemetics; D004040:Dietary Carbohydrates; D009020:Morphine