title: Frequency-doubling technology perimetry and multifocal visual evoked potential in glaucoma, suspected glaucoma, and control patients.
abstract: BACKGROUND
  The gold standard in functional glaucoma evaluation is standard automated perimetry (SAP). However, SAP depends on the reliability of the patients' responses and other external factors; therefore, other technologies have been developed for earlier detection of visual field changes in glaucoma patients. The frequency-doubling perimetry (FDT) is believed to detect glaucoma earlier than SAP. The multifocal visual evoked potential (mfVEP) is an objective test for functional evaluation.
  
  
  OBJECTIVE
  To evaluate the sensitivity and specificity of FDT and mfVEP tests in normal, suspect, and glaucomatous eyes and compare the monocular and interocular mfVEP.
  
  
  METHODS
  Ninety-five eyes from 95 individuals (23 controls, 33 glaucoma suspects, 39 glaucomatous) were enrolled. All participants underwent a full ophthalmic examination, followed by SAP, FDT, and mfVEP tests.
  
  
  RESULTS
  The area under the curve for mean deviation and pattern standard deviation were 0.756 and 0.761, respectively, for FDT, 0.564 and 0.512 for signal and alpha for interocular mfVEP, and 0.568 and 0.538 for signal and alpha for monocular mfVEP. This difference between monocular and interocular mfVEP was not significant.
  
  
  CONCLUSIONS
  The FDT Matrix was superior to mfVEP in glaucoma detection. The difference between monocular and interocular mfVEP in the diagnosis of glaucoma was not significant.
authors: Federal University of Sao Paulo, Sao Paulo, Brazil.
authors: Fabio N
authors: FN
authors: Kanadani
authors: Federal University of Sao Paulo, Sao Paulo, Brazil.
authors: Paulo Aa
authors: PA
authors: Mello
authors: Mayo Clinic, Department of Ophthalmology, Jacksonville, Florida, USA.
authors: Syril K
authors: SK
authors: Dorairaj
authors: Sao Jose University Hospital, Belo Horizonte, Brazil.
authors: Tereza Cm
authors: TC
authors: Kanadani
keywords: electrophysiology; glaucomatous eyes; standard automated perimetry