title: Fasting and postprandial glucose, insulin, leptin, and ghrelin values in preterm babies and their mothers: relationships among their levels, fetal growth, and neonatal anthropometry.
abstract: OBJECTIVE
  To investigate relationship between anthropometric values of premature babies with their's glucose, insulin, leptin, and ghrelin at birth and on day 15.
  
  
  METHODS
  We analyzed fasting and postprandial glucose, insulin, leptin, and ghrelin levels at birth and on day 15 in babies born prematurely between 24 and 37 weeks, and who did not have serious problems aside from prematurity at birth.
  
  
  RESULTS
  Fasting glucose, insulin, leptin and ghrelin values of babies at birth and on day 15 were significantly lower than postprandial values (all p values p < 0.001). There were positive correlations between the mean insulin, leptin, and ghrelin levels with the gestational age, birth weight, body mass index, head circumference of babies at birth, and anthropometric values on day 15 (all r values > 0.400, all p values < 0.05). Fasting glucose, leptin, and ghrelin values of mothers birth were significantly lower than post-prandial values (all p values p < 0.05).
  
  
  CONCLUSIONS
  The positive correlations between the insulin, leptin, and ghrelin values of babies at birth with gestational age and anthropometric values suggest that both hormones play important roles in fetal and neonatal growth and development.
authors: Department of Neonatal Intensive Care Unit, Erzurum District Training and Research Hospital , Erzurum , Turkey .
authors: Hasan
authors: H
authors: Kahveci
authors: Fuat
authors: F
authors: Laloglu
authors: Omer
authors: O
authors: Kilic
authors: Murat
authors: M
authors: Ciftel
authors: Mustafa
authors: M
authors: Kara
authors: Esra
authors: E
authors: Laloglu
authors: Abdulkadir
authors: A
authors: Yildirim
authors: Zerrin
authors: Z
authors: Orbak
authors: Vildan
authors: V
authors: Ertekin
authors: Yasar
authors: Y
authors: Cesur
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001724:Birth Weight; D001786:Blood Glucose / Q000378:metabolism*; D015992:Body Mass Index; D016022:Case-Control Studies; D005215:Fasting; D005260:Female; D047109:Fetal Development / Q000502:physiology*; D005865:Gestational Age; D054439:Ghrelin / Q000097:blood*; D006257:Head / Q000033:anatomy & histology; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000097:blood*; D007328:Insulin / Q000097:blood*; D020738:Leptin / Q000097:blood*; D008297:Male; D011446:Prospective Studies
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D054439:Ghrelin; D007328:Insulin; D020738:Leptin
keywords: Fasting; ghrelin; glucose; insulin; leptin; premature newborn