title: Choroidal thickness changes in patients with pseudoexfoliation syndrome.
abstract: To evaluate the choroidal thickness using spectral-domain optical coherence tomography (OCT) in patients with pseudoexfoliation syndrome (PXS) and to compare them with healthy controls. This observational comparative study consisted of 35 PXS patients and 35 age- and sex-matched control cases. The control cases had neither systemic nor ocular disease. All 70 patients underwent a complete ophthalmic examination as well as choroidal thickness measurement using a high speed and high resolution SD-OCT device (Topcon 3D OCT-2000, Japan). There was no significant difference with respect to mean refractive error and intraocular pressure measurement between patients with PXS and controls (p = 0.237 and 0.433, respectively). The mean choroidal thickness was found as 206.6 ± 37.6 µm in the PXS group and 215.9 ± 47.3 µm in controls, respectively. The mean choroidal thickness was not significant between the PXS patients and the control cases (p = 0.362). Although PXS patients had lower mean choroidal thickness than controls, our results did not reach any statistical significance.
authors: Department of Ophtalmology, Izmir University Faculty of Medicine, Gursel Aksel Bulvarı, No. 14, Uckuyular, 35350, Izmir, Turkey, mehmetozgurzengin@yahoo.com.
authors: Mehmet Ozgur
authors: MO
authors: Zengin
authors: Esat
authors: E
authors: Cinar
authors: Eyyup
authors: E
authors: Karahan
authors: Ibrahim
authors: I
authors: Tuncer
authors: Sami
authors: S
authors: Yilmaz
authors: Tolga
authors: T
authors: Kocaturk
authors: Cem
authors: C
authors: Kucukerdonmez
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D002829:Choroid / Q000473:pathology*; D017889:Exfoliation Syndrome / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D012030:Refractive Errors / Q000503:physiopathology; D041623:Tomography, Optical Coherence / Q000379:methods