title: Perceived social support following myocardial infarction and long-term development of frailty.
abstract: OBJECTIVE
  Frailty is a multidimensional geriatric syndrome that indicates increasing vulnerability and decreasing resistance to stressors. Social support (SS) is linked both to cardiovascular disease and to frailty. However, few cohort studies evaluated SS as a potential predictor of frailty, and none involved coronary disease populations. The aim of this study was to evaluate the role of perceived SS (PSS) - a specific component of SS - in the prediction of frailty development in myocardial infarction (MI) survivors, controlling for other psychosocial risk factors.
  
  
  METHODS
  A cohort of 558 patients aged ≤65 years, admitted for first-ever MI to hospitals in central Israel, was studied. PSS and other clinical and sociodemographic variables were assessed at baseline. Frailty was assessed via a frailty index of deficit accumulation 10-13 years later. Logistic regression models were constructed to assess the odds ratios (OR) for frailty associated with PSS as well as other covariates.
  
  
  RESULTS
  At last follow-up, 154 (28%) met the criteria for frailty. In the logistic regression models, higher PSS level was associated with lower frailty risk (unadjusted OR = 0.63, 95%CI 0.53-0.76; multivariable-adjusted OR = 0.80, 95%CI 0.64-0.98). Below average family income, poor self-rated health and higher depression scores were all associated with the development of frailty, in both the unadjusted and adjusted models.
  
  
  CONCLUSIONS
  PSS predicts frailty development post-MI, which has important implications for prognosis and healthcare use.
authors: Shalvata Mental Health Centre, Hod Hasharon, Israel Department of Psychiatry, Sackler Medical School, Tel Aviv University, Israel Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Medical School, Tel Aviv University, Israel ido.lurie@gmail.com.
authors: Ido
authors: I
authors: Lurie
authors: Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Medical School, Tel Aviv University, Israel.
authors: Vicki
authors: V
authors: Myers
authors: Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Medical School, Tel Aviv University, Israel.
authors: Uri
authors: U
authors: Goldbourt
authors: Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Medical School, Tel Aviv University, Israel.
authors: Yariv
authors: Y
authors: Gerber
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D016009:Chi-Square Distribution; D016330:Frail Elderly / Q000523:psychology*; D015577:Geriatric Assessment; D006801:Humans; D007557:Israel; D016014:Linear Models; D016015:Logistic Models; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology* / Q000628:therapy; D016017:Odds Ratio; D010465:Perception; D011379:Prognosis; D011446:Prospective Studies; D012307:Risk Factors; D055502:Secondary Prevention / Q000379:methods; D012944:Social Support; D013997:Time Factors
keywords: Myocardial infarction; epidemiology; frailty; perceived social support; secondary prevention