title: Discrete nanoparticles of ruta graveolens induces the bacterial and fungal biofilm inhibition.
abstract: Ruta graveolens silver nanoparticles (AgNPs) showed the color change within 30 min and characterized using UV-visible spectra, Fourier Transform Infrared (FTIR), X-ray Diffraction (XRD) and Transmission Electron Microscopy (TEM). UV-visible spectrum of R. graveolens AgNPs showed the sharp peak at the wavelength of 440-560 nm. XRD patterns confirmed that crystalline nature of R. graveolens AgNPs and FTIR results revealed that phytochemical reaction of these R. graveolens is responsible for the synthesis of AgNPs. TEM results showed the size of the R. graveolens AgNPs around 30-50 nm with spherical and triangular nature. Further, the antibacterial and antibiofilm activity of R. graveolens AgNPs showed the effective inhibitory activity against clinically important Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans. Our findings suggest that R. graveolens AgNPs can be exploited toward the development of potential antibacterial agents for various biomedical and environmental applications.
authors: Crustacean Molecular Biology and Genomics Lab, Department of Animal Health and Management, Alagappa University , Karaikudi, Tamil Nadu , India.
authors: Jeyachandran
authors: J
authors: Sivakamavalli
authors: Oyyappan
authors: O
authors: Deepa
authors: Baskaralingam
authors: B
authors: Vaseeharan
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology*; D018441:Biofilms / Q000187:drug effects*; D002176:Candida albicans / Q000187:drug effects / Q000502:physiology; D052978:Disk Diffusion Antimicrobial Tests; D053758:Nanoparticles; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000502:physiology; D032105:Ruta / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000502:physiology
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D010936:Plant Extracts
keywords: R. graveolens; antibacterial activity; biofilm; cell adhesion; green synthesis; silver nanoparticles