title: Clinical outcome and immune follow-up of different surgical approaches for human cyst hydatid disease in liver.
abstract: A new surgical approach (subadventitial cystectomy) has been developed for liver hydatid disease. We retrospectively compared clinical outcomes and immune status 24 months after a subadventitial cystectomy with traditional surgical approaches. Patients with liver hydatid cysts were treated with a subadventitial cystectomy (N = 11), pericystectomy (N = 16), partial pericystectomy (N = 18), or hepatic resection (N = 12). By the end of the follow-up period, the subadventitial cystectomy group had the fewest post-operative complications and shortest hospital stays. Two recurrences occurred: one recurrence after partial pericystectomy and one recurrence after pericystectomy. The total immunoglobulin E (IgE) level decreased significantly in the subadventitial cystectomy group. The post-surgery IgG level was lower in the subadventitial cystectomy than the pericystectomy and partial pericystectomy groups. In conclusion, subadventitial cystectomy completely removes the parasite, causing lower complication rates and lower immune reactions.
authors: Department of Hepatobiliary Surgery, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Department of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan Shandong, China; Xinjiang Key Laboratory of Echinococcosis, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
authors: Xinhua
authors: X
authors: Chen
authors: Department of Hepatobiliary Surgery, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Department of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan Shandong, China; Xinjiang Key Laboratory of Echinococcosis, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
authors: Xinmei
authors: X
authors: Chen
authors: Department of Hepatobiliary Surgery, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Department of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan Shandong, China; Xinjiang Key Laboratory of Echinococcosis, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
authors: Yingmei
authors: Y
authors: Shao
authors: Department of Hepatobiliary Surgery, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Department of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan Shandong, China; Xinjiang Key Laboratory of Echinococcosis, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
authors: Jingming
authors: J
authors: Zhao
authors: Department of Hepatobiliary Surgery, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Department of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan Shandong, China; Xinjiang Key Laboratory of Echinococcosis, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
authors: Haitao
authors: H
authors: Li
authors: Department of Hepatobiliary Surgery, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Department of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan Shandong, China; Xinjiang Key Laboratory of Echinococcosis, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China wenhao@superinfo.info.
authors: Hao
authors: H
authors: Wen
mesh_terms: D000328:Adult; D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D000923:Anticestodal Agents / Q000627:therapeutic use; D015653:Cystectomy / Q000379:methods*; D004444:Echinococcosis, Hepatic / Q000276:immunology / Q000469:parasitology / Q000601:surgery*; D004446:Echinococcus / Q000302:isolation & purification*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007902:Length of Stay; D008099:Liver / Q000276:immunology / Q000469:parasitology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies
chemical_list: D000923:Anticestodal Agents; D007074:Immunoglobulin G; D007073:Immunoglobulin E; D015766:Albendazole