title: Assessment of coronary artery disease using coronary computed tomography angiography and biochemical markers.
abstract: Chronic inflammatory mechanisms in the arterial wall lead to atherosclerosis, and include endothelial cell damage, inflammation, apoptosis, lipoprotein deposition, calcification and fibrosis. Cardiac computed tomography angiography (CCTA) has been shown to be a promising tool for non-invasive assessment of theses specific compositional and structural changes in coronary arteries. This review focuses on the technical background of CCTA-based quantitative plaque characterization. Furthermore, we discuss the available evidence for CCTA-based plaque characterization and the potential role of CCTA for risk stratification of patients with coronary artery disease.
authors: Gitsios Gitsioudis, Hugo A Katus, Grigorios Korosoglou, Department of Cardiology, University of Heidelberg, 69120 Heidelberg, Germany.
authors: Gitsios
authors: G
authors: Gitsioudis
authors: Gitsios Gitsioudis, Hugo A Katus, Grigorios Korosoglou, Department of Cardiology, University of Heidelberg, 69120 Heidelberg, Germany.
authors: Hugo A
authors: HA
authors: Katus
authors: Gitsios Gitsioudis, Hugo A Katus, Grigorios Korosoglou, Department of Cardiology, University of Heidelberg, 69120 Heidelberg, Germany.
authors: Grigorios
authors: G
authors: Korosoglou
keywords: Atherosclerotic plaque composition; Biomarkers; Multi-slice cardiac computed tomography; Quantification analysis