title: Immunophenotypic characterization of canine malignant lymphoma: a retrospective study of cases diagnosed in Poland Lower Silesia, over the period 2011-2013.
abstract: Lymphoma is the most frequently diagnosed cancer of the canine haematopoietic system. In this study, the flow cytometry and polymerase chain reaction (PCR) analysis were used to characterize a series of canine lymphomas in detail. The aim of this study was to determine the incidence of B- and T-cell high-grade lymphomas and their immunophenotypic characterization in Lower Silesia, Poland. The results show that the frequency of each type of lymphoma is 71% for B-cell and 17% for T-cell lymphomas. In two cases the PCR techniques confirmed the presence of simultaneous double gene rearrangements of the BCR and TCR receptors.
authors: Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland.
authors: A
authors: A
authors: Pawlak
authors: Laboratory of Tumor Molecular Immunobiology, Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Wroclaw, Poland.
authors: A
authors: A
authors: Rapak
authors: Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland.
authors: A
authors: A
authors: Drynda
authors: Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland.
authors: D
authors: D
authors: Poradowski
authors: Laboratory of Flow Cytometry, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland.
authors: I
authors: I
authors: Zbyryt
authors: Department of Pathology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland.
authors: S
authors: S
authors: Dzimira
authors: Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland.
authors: J
authors: J
authors: Suchański
authors: Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland.
authors: B
authors: B
authors: Obmińska-Mrukowicz
mesh_terms: D000818:Animals; D015703:Antigens, CD / Q000032:analysis; D004283:Dog Diseases / Q000453:epidemiology* / Q000235:genetics / Q000473:pathology*; D004285:Dogs; D005434:Flow Cytometry / Q000662:veterinary; D019672:Genes, T-Cell Receptor / Q000235:genetics; D016130:Immunophenotyping / Q000662:veterinary; D016393:Lymphoma, B-Cell / Q000453:epidemiology / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D016399:Lymphoma, T-Cell / Q000453:epidemiology / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D011044:Poland / Q000453:epidemiology; D016133:Polymerase Chain Reaction; D051562:Proto-Oncogene Proteins c-bcr / Q000235:genetics; D012189:Retrospective Studies; D012582:Schools, Veterinary
chemical_list: D015703:Antigens, CD; D051562:Proto-Oncogene Proteins c-bcr
keywords: PCR; canine lymphoma; flow cytometry; immunophenotyping