title: PhI(OAc)2-mediated intramolecular oxidative aryl-aldehyde Csp(2)-Csp(2) bond formation: metal-free synthesis of acridone derivatives.
abstract: A metal-free protocol for direct aryl-aldehyde Csp(2)-Csp(2) bond formation via a PhI(OAc)2-mediated intramolecular cross-dehydrogenative coupling (CDC) of various 2-(N-arylamino)aldehydes was developed. The novel methodology requires no need of preactivation of the aldehyde group, is applicable to a large variety of functionalized substrates, and most of all provides a convenient approach to the construction of biologically important acridone derivatives.
authors: Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University , Tianjin 300072, China.
authors: Zisheng
authors: Z
authors: Zheng
authors: Longyang
authors: L
authors: Dian
authors: Yucheng
authors: Y
authors: Yuan
authors: Daisy
authors: D
authors: Zhang-Negrerie
authors: Yunfei
authors: Y
authors: Du
authors: Kang
authors: K
authors: Zhao