title: Successful chemotherapy with nab-Paclitaxel in a heavily treated non-small cell lung cancer patient: a case report.
abstract: Non-small cell lung cancer (NSCLC) accounts for the majority of all lung cancers. A 69-year-old female with postoperatively recurrent NSCLC was treated weekly with nanoparticle-albumin-bound paclitaxel (nab-paclitaxel) monotherapy every 4 weeks as a tenth line chemotherapy, and stable disease was achieved by seven cycles of this regimen. The patient developed grade 4 neutropenia and grade 3 leukopenia, but none of the other toxicities, including febrile neutropenia and peripheral neuropathy, were severe, and thus she was able to tolerate this salvage chemotherapy. To our knowledge this is the first report of the efficacy of nab-paclitaxel monotherapy in a heavily treated NSCLC patient.
authors: Department of Respiratory Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
authors: Mikiko
authors: M
authors: Ishihara
authors: Department of Respiratory Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
authors: Satoshi
authors: S
authors: Igawa
authors: Department of Respiratory Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
authors: Sachiyo
authors: S
authors: Maki
authors: Department of Respiratory Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
authors: Shinya
authors: S
authors: Harada
authors: Department of Respiratory Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
authors: Seiichiro
authors: S
authors: Kusuhara
authors: Department of Respiratory Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
authors: Hideyuki
authors: H
authors: Niwa
authors: Department of Respiratory Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
authors: Sakiko
authors: S
authors: Otani
authors: Research and Development Center for New Medical Frontiers, Kitasato University School of Medicine, Sagamihara, Japan.
authors: Jiichiro
authors: J
authors: Sasaki
authors: Department of Pathology, Kitasato University School of Medicine, Sagamihara, Japan.
authors: Shi-Xu
authors: SX
authors: Jiang
authors: Department of Respiratory Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
authors: Noriyuki
authors: N
authors: Masuda
keywords: Chemotherapy; Nab-paclitaxel; Non-small cell lung cancer