title: Biomarker studies in multiple sclerosis: from proteins to noncoding RNAs.
abstract: Multiple sclerosis (MS) is a neuroimmunological disorder characterized by central nervous system demyelination, axonal injury and loss. Considering the complexity of its aetiopathogenesis, early diagnosis of MS and individualized management are challenging in clinical practice. As the pathophysiologic and pharmacological indicators, studies on biomarkers in MS are useful for early prediction and diagnosis, monitoring of disease activity and predicting treatment response. In this review, we will summarize recent development of biomarker studies in MS from protein molecules to noncoding RNAs.
authors: Department of Neurology, Xiangya Hospital, Central South University, Changsha, 410008, China.
authors: Xiao-Fang
authors: XF
authors: Liu
authors: Yue-Bei
authors: YB
authors: Luo
authors: Zhao-Hui
authors: ZH
authors: Luo
authors: Huan
authors: H
authors: Yang
mesh_terms: D015415:Biomarkers / Q000378:metabolism*; D006801:Humans; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism*; D022661:RNA, Untranslated / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D011506:Proteins; D022661:RNA, Untranslated