title: Is the LINX reflux management system an effective treatment for gastro-oesophageal reflux disease?
abstract: A best evidence topic in surgery was written according to a structured protocol. The question addressed whether LINX™ Reflux management system is an efficacious treatment for patients with symptoms of gastro-oesophageal reflux disease (GORD) not controlled by proton pump inhibitors (PPI). Forty-eight LINX-related papers were identified using the reported search, of which three represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group, study type, relevant outcomes and results of these papers are tabulated. All three studies were prospective case studies. They demonstrated that LINX is an efficacious treatment for GORD patients with good short and medium term outcomes and an acceptable safety profile. Further studies are required to determine its long term outcomes and its relative efficacy as compared to other established treatments.
authors: Department of Upper GI Surgery, St Georges Hospital, Blackshaw Road, London SW17 0QT, UK.
authors: Yiwen
authors: Y
authors: Loh
authors: Department of Upper GI Surgery, St Georges Hospital, Blackshaw Road, London SW17 0QT, UK.
authors: Emma Rose
authors: ER
authors: McGlone
authors: Department of Upper GI Surgery, St Georges Hospital, Blackshaw Road, London SW17 0QT, UK.
authors: Marcus
authors: M
authors: Reddy
authors: Department of Upper GI Surgery, St Georges Hospital, Blackshaw Road, London SW17 0QT, UK. Electronic address: okhan342@gmail.com.
authors: Omar A
authors: OA
authors: Khan
mesh_terms: D005764:Gastroesophageal Reflux / Q000188:drug therapy / Q000601:surgery*; D005765:Gastrointestinal Agents / Q000627:therapeutic use; D006801:Humans; D055909:Magnetic Field Therapy / Q000295:instrumentation*; D011446:Prospective Studies; D054328:Proton Pump Inhibitors / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D005765:Gastrointestinal Agents; D054328:Proton Pump Inhibitors
keywords: GERD; GORD; LINX; MSA; Magnetic sphincter augmentation; Magnetic sphincter device