title: Clinical analysis of port-wine stain in 130 Chinese patients treated by long-pulsed 1064-nm Nd: YAG laser.
abstract: BACKGROUND
  The long-pulsed 1064-nm Nd: YAG laser is effective for treating port-wine stain (PWS). This study evaluated the efficacy and safety of Nd: YAG laser in treating PWS in Chinese patients.
  
  
  METHODS
  A retrospective study of 130 PWS patients treated with long-pulsed 1064-nm Nd: YAG laser from 2009 to 2011.
  
  
  RESULTS
  After treatment, 2, 15, 64, and 19 percent of patients experienced < 25%, 25-49%, 50-75%, and > 75% lesion clearance, respectively. Purple lesions showed more significant improvement than pink lesions. The initial response was blistering, dark gray coloration, or light gray coloration, the best improvement occurred in 100% (27/27), 82.5% (52/63), and 72.5% (29/40), respectively. Patients older than 20 years showed the best improvement (37/38, 97.4%), followed by those 10-20 years old (20/24, 83.3%), 1-9 years old (23/29, 79.3%) and less than 1 year old (28/39, 71.8%). Patients with neck lesions had the best outcome (47/48, 97.9%), followed by those with lesions on the face (43/53, 81.2%), extremities (13/18, 72.2%), and trunk (5/11, 45.5%). The common adverse side effects were blistering and pigment changes.
  
  
  CONCLUSIONS
  1064-nm Nd: YAG laser is effective and safe for the treatment of PWS. The efficacy is affected by the age of the patient, the color and location of the lesions, and immediate responses to the laser.
authors: Department of Dermatology and Venereology, First Hospital of Jilin University , Changchun , P. R. China.
authors: Shu-Xia
authors: SX
authors: Zhong
authors: Yuan-Yuan
authors: YY
authors: Liu
authors: Lei
authors: L
authors: Yao
authors: Yang
authors: Y
authors: Song
authors: Jun-Feng
authors: JF
authors: Zhou
authors: Jian-Jiao
authors: JJ
authors: Zu
authors: Shan-Shan
authors: SS
authors: Li
mesh_terms: D000293:Adolescent; D000328:Adult; D044466:Asian People; D002648:Child; D002675:Child, Preschool; D002681:China; D003357:Cosmetic Techniques / Q000295:instrumentation; D005145:Face; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D053844:Lasers, Solid-State / Q000009:adverse effects / Q000627:therapeutic use*; D028022:Low-Level Light Therapy / Q000009:adverse effects / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009333:Neck; D019339:Port-Wine Stain / Q000532:radiotherapy*; D012189:Retrospective Studies; D055815:Young Adult
keywords: 1064-nm Nd: YAG laser; birthmark; influencing factor; laser therapeutic efficacy; nevus flammeus; port-wine stain