title: [Ultra-sensitive C-reactive protein associated to nutritional status and biochemical profile in Mexican shoolchildren].
abstract: BACKGROUND
  C-reactive protein (CRP) is a nonspecific marker of inflammation with low serum levels, which are not usually detectable. In order to assess cardiovascular risk in adults apparently healthy, ultrasensitive methods are used, and the CRP measured through these techniques is known as ultrasensitive C-reactive protein (US-CRP). Some researchers report an association of US-CRP with some anthropometric parameters in children with no apparent disease. The aim was to associate US-CRP with nutritional status and biochemical profiles in Mexican schoolchildren.
  
  
  METHODS
  In this cross-sectional study 300 healthy children (aged 10 to 12 years) were evaluated. Weight, height, body mass index (BMI), waist circumference, body fat percentage, glucose, lipid profiles and US-CRP were measured. Exclusion criteria was: US-CRP > 10mg/L. We used multivariate regression models.
  
  
  RESULTS
  53.7 % were girls and 46.3 % were boys. The US-CRP median was of 0.3 mg/L (range: 0.3 mg/L-6.8 mg/L), and it was positively and significantly correlated with BMI (ß = 0.226, p = 0.032) and LDL-C (ß = -0.267, p = 0.007) and negatively associated with cholesterol (ß = -0.267, p = 0.007).
  
  
  CONCLUSIONS
  There is an association between US-CRP and cardiovascular risk indicators, such as obesity and some lipid disorder in childhood; therefore, US-CRP may be used for close examination in Mexican children.
authors: Departamento de Planeación y Enlace Institucional, Delegación Baja California, Instituto Mexicano del Seguro Social, Baja California, México. josefinaruizesparza@uabc.edu.mx.
authors: María Elena
authors: ME
authors: Haro-Acosta
authors: Josefina
authors: J
authors: Ruíz Esparza-Cisneros
authors: Jesús Hernán
authors: JH
authors: Delgado-Valdez
authors: Raúl
authors: R
authors: Díaz-Molina
authors: Rafael Iván
authors: RI
authors: Ayala-Figueroa
mesh_terms: D015415:Biomarkers / Q000097:blood; D001827:Body Height; D015992:Body Mass Index; D001835:Body Weight; D002097:C-Reactive Protein / Q000378:metabolism*; D002318:Cardiovascular Diseases / Q000097:blood / Q000209:etiology; D002648:Child; D002784:Cholesterol / Q000097:blood; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000175:diagnosis; D008297:Male; D008800:Mexico; D009752:Nutritional Status / Q000502:physiology*; D009765:Obesity / Q000097:blood / Q000175:diagnosis; D018570:Risk Assessment; D055105:Waist Circumference
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein; D002784:Cholesterol
keywords: Body mass index; C-reactive protein; Child, Mexico; Nutritional status