title: Stereotactic body radiotherapy: a new paradigm in the management of spinal metastases.
abstract: Spine stereotactic body radiotherapy is based on delivering high biologically effective doses to spinal metastases, with the intent to maximize both tumor and pain control. The purpose of this review is to outline the technical details of spine stereotactic body radiotherapy, contrast clinical outcomes to low biologically effective dose conventional palliative radiotherapy, discuss the role of surgery in the era of spine stereotactic body radiotherapy, and summarize the major serious adverse events that patients would otherwise not be at risk of with conventional radiotherapy.
authors: Department of Radiation Oncology, Yale School of Medicine, New Haven, CT, USA.
authors: Zain A
authors: ZA
authors: Husain
authors: Isabelle
authors: I
authors: Thibault
authors: Daniel
authors: D
authors: Letourneau
authors: Lijun
authors: L
authors: Ma
authors: Harald
authors: H
authors: Keller
authors: John
authors: J
authors: Suh
authors: Veronica
authors: V
authors: Chiang
authors: Eric L
authors: EL
authors: Chang
authors: Raja K
authors: RK
authors: Rampersaud
authors: James
authors: J
authors: Perry
authors: David A
authors: DA
authors: Larson
authors: Arjun
authors: A
authors: Sahgal
mesh_terms: D006801:Humans; D016634:Radiosurgery / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D011880:Radiotherapy Planning, Computer-Assisted; D016032:Randomized Controlled Trials as Topic; D013125:Spinal Neoplasms / Q000473:pathology / Q000556:secondary* / Q000601:surgery*