title: Effects of Rosmarinus officinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers.
abstract: BACKGROUND
  The aim of this study was to investigate the effects of Rosmarinus officinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers.
  
  
  METHODS
  Ten C. albicans isolates recovered from denture wearers were tested using 10% fetal bovine serum with or without 4% R. officinalis essential oil.
  
  
  RESULTS
  The essential oil from R. officinalis completely inhibited germ tube formation in the investigated C. albicans isolates.
  
  
  CONCLUSIONS
  The results demonstrate that the essential oil of R. officinalis modulates C. albicans pathogenicity through its primary virulence factor (i.e., germ tube formation was suppressed).
authors: Programa de Pós-Graduação em Biologia de Agentes Infecciosos de Parasitários, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, PA, Brazil.
authors: Lurdete Maria Rocha
authors: LM
authors: Gauch
authors: Programa de Pós-Graduação em Biologia de Agentes Infecciosos de Parasitários, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, PA, Brazil.
authors: Fabíola
authors: F
authors: Silveira-Gomes
authors: Faculdade de Odontologia, Instituto de Ciências da Saúde, Universidade Federal do Pará, Belém, PA, Brazil.
authors: Renata Antunes
authors: RA
authors: Esteves
authors: Faculdade de Odontologia, Instituto de Ciências da Saúde, Universidade Federal do Pará, Belém, PA, Brazil.
authors: Simone Soares
authors: SS
authors: Pedrosa
authors: Laboratório de Botânica, Museu Paraense Emílio Goeldi, Belém, PA, Brazil.
authors: Ely Simone Cajueiro
authors: ES
authors: Gurgel
authors: Laboratório Central de Extração, Instituto de Ciências Exatas e Naturais, Universidade federal do Pará, Belém, PA, Brazil.
authors: Alberto Cardoso
authors: AC
authors: Arruda
authors: Laboratório de Micologia, Seção de Bacteriologia e Micologia, Instituto Evandro Chagas, Belém, PA, Brazil.
authors: Silvia Helena
authors: SH
authors: Marques-da-Silva
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects* / Q000302:isolation & purification; D003778:Dentures / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009822:Oils, Volatile / Q000494:pharmacology*; D027542:Rosmarinus / Q000737:chemistry*
chemical_list: D000935:Antifungal Agents; D009822:Oils, Volatile