title: Factors associated with high rates of antiretroviral medication adherence among youth living with perinatal HIV in Thailand.
abstract: Antiretroviral medication adherence behaviour among Thai youth with perinatal HIV in Thailand has received growing attention. However, few studies have examined individual predictors of antiretroviral adherence using multiple self-reports. A convenience sample of 89 Thai youth (interquartile range 14-16 years) with perinatal HIV at three paediatric programmes in Chiang Mai completed a structured questionnaire and reported their antiretroviral adherence in the past one, seven and 30 days using count-based recall and a visual analog scale. Mean self-reported adherence rates ranged from 83.5% (past 30 days) to 99.8% (yesterday) of the time. One-inflated beta regression models were used to examine the associations between antiretroviral adherence outcomes, treatment self-efficacy, depression, anxiety, social support and beliefs/attitudes about medications. Higher percentage of medications taken in the past 30 days was independently associated with higher treatment self-efficacy and fewer symptoms of depression. Adherence monitoring would benefit from focal assessment of youth depression and perceived capacity to follow their antiretroviral regimen.
authors: Department of Psychology, Wheaton College, Wheaton, IL, USA.
authors: Ezer
authors: E
authors: Kang
authors: Department of Mathematics and Computer Science, Wheaton College, Wheaton, IL, USA.
authors: Darcie A P
authors: DA
authors: Delzell
authors: Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT, USA.
authors: Manik
authors: M
authors: Chhabra
authors: Division of Pediatric Infectious Diseases, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand aoberdor@med.cmu.ac.th.
authors: Peninnah
authors: P
authors: Oberdorfer
mesh_terms: D000293:Adolescent; D019380:Anti-HIV Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D001007:Anxiety / Q000175:diagnosis / Q000523:psychology; D002648:Child; D003430:Cross-Sectional Studies; D003863:Depression / Q000175:diagnosis / Q000523:psychology; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000208:ethnology / Q000523:psychology; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D016015:Logistic Models; D008297:Male; D055118:Medication Adherence / Q000208:ethnology; D020377:Self Efficacy; D012944:Social Support; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D013785:Thailand / Q000453:epidemiology; D019562:Viral Load; D016903:Drug Monitoring
chemical_list: D019380:Anti-HIV Agents
keywords: AIDS; HIV; Thailand; antiretroviral therapy; medication adherence; treatment; youth