title: Bioprinting technology and its applications.
abstract: Bioprinting technology has emerged as a powerful tool for building tissue and organ structures in the field of tissue engineering. This technology allows precise placement of cells, biomaterials and biomolecules in spatially predefined locations within confined three-dimensional (3D) structures. Various bioprinting technologies have been developed and utilized for applications in life sciences, ranging from studying cellular mechanisms to constructing tissues and organs for implantation, including heart valve, myocardial tissue, trachea and blood vessels. In this article, we introduce the general principles and limitations of the most widely used bioprinting technologies, including jetting- and extrusion-based systems. Application-based research focused on tissue regeneration is presented, as well as the current challenges that hamper clinical utility of bioprinting technology.
authors: Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine Medical Center Boulevard, Winston-Salem, NC, USA.
authors: Young-Joon
authors: YJ
authors: Seol
authors: Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine Medical Center Boulevard, Winston-Salem, NC, USA.
authors: Hyun-Wook
authors: HW
authors: Kang
authors: Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine Medical Center Boulevard, Winston-Salem, NC, USA.
authors: Sang Jin
authors: SJ
authors: Lee
authors: Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine Medical Center Boulevard, Winston-Salem, NC, USA.
authors: Anthony
authors: A
authors: Atala
authors: Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine Medical Center Boulevard, Winston-Salem, NC, USA jyoo@wakehealth.edu.
authors: James J
authors: JJ
authors: Yoo
mesh_terms: D062028:Bioprinting; D002478:Cells, Cultured; D006801:Humans; D044968:Regenerative Medicine; D023822:Tissue Engineering
keywords: Bioprinting; Reconstruction; Regenerative medicine