title: Sarcomatoid carcinoma of the lung: a model of resistance of chemotherapy.
abstract: BACKGROUND
  Lung tumors are very heterogeneous histological entities. Pulmonary sarcomatoid carcinoma is a subset of tumors characterized by specific histological features. Their poor prognosis compared to other lung tumors is due to limited responses to different types of chemotherapy.
  
  
  METHODS
  WE REPORT TWO PATIENTS WITH SARCOMATOID TUMORS: A 53-year-old woman and a 46-year-old man who presented respiratory symptoms: Dyspnea, cough, associated with a deterioration of general condition.
  
  
  CONCLUSIONS
  Pulmonary sarcomatoid carcinomas remained an unexplored entity, despite their poor prognosis. Based on these cases, we will discuss the histological and immunohistochemical features of these tumors, as well as report their responses to different chemotherapy regimens used in the course of treatment.
authors: Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco ; Jules Bordet Institute, Brussels, Belgium.
authors: Imane
authors: I
authors: Ouziane
authors: Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
authors: Saber
authors: S
authors: Boutayeb
authors: Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
authors: Hind
authors: H
authors: Mrabti
authors: Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
authors: Issam
authors: I
authors: Lalya
authors: Department of Pathology, Hassan Loboratory, Rabat, Morocco.
authors: Mouna
authors: M
authors: Rimani
authors: Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
authors: Hassan
authors: H
authors: Errihani
keywords: Chemotherapy; lung; response to platinum salts; saromatoid carcinoma; surgery; targeted therapy