title: Sequence types 235, 111, and 132 predominate among multidrug-resistant pseudomonas aeruginosa clinical isolates in Croatia.
abstract: A population analysis of 103 multidrug-resistant Pseudomonas aeruginosa isolates from Croatian hospitals was performed. Twelve sequence types (STs) were identified, with a predominance of international clones ST235 (serotype O11 [41%]), ST111 (serotype O12 [15%]), and ST132 (serotype O6 [11%]). Overexpression of the natural AmpC cephalosporinase was common (42%), but only a few ST235 or ST111 isolates produced VIM-1 or VIM-2 metallo-β-lactamases or PER-1 or GES-7 extended-spectrum β-lactamases.
authors: University Hospital for Infectious Diseases, Zagreb, Croatia marija.guzvinec@bfm.hr.
authors: Marija
authors: http://orcid.org/0000-0002-5920-8223
authors: M
authors: Guzvinec
authors: National Medicines Institute, Warsaw, Poland.
authors: Radosław
authors: R
authors: Izdebski
authors: University Hospital for Infectious Diseases, Zagreb, Croatia.
authors: Iva
authors: I
authors: Butic
authors: University Hospital for Infectious Diseases, Zagreb, Croatia.
authors: Marko
authors: M
authors: Jelic
authors: Clinical Hospital Centre Rijeka, Rijeka, Croatia.
authors: Maja
authors: M
authors: Abram
authors: Institute of Public Health, Varazdin, Croatia.
authors: Iva
authors: I
authors: Koscak
authors: National Medicines Institute, Warsaw, Poland.
authors: Anna
authors: A
authors: Baraniak
authors: National Medicines Institute, Warsaw, Poland.
authors: Waleria
authors: W
authors: Hryniewicz
authors: National Medicines Institute, Warsaw, Poland.
authors: Marek
authors: M
authors: Gniadkowski
authors: University Hospital for Infectious Diseases, Zagreb, Croatia.
authors: Arjana
authors: A
authors: Tambic Andrasevic
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002510:Cephalosporinase / Q000235:genetics; D017523:Croatia; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000201:enzymology* / Q000235:genetics; D001618:beta-Lactamases / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D002510:Cephalosporinase; D001618:beta-Lactamases