title: Primary small cell neuroendocrine carcinoma of paranasal sinuses.
abstract: Small cell neuroendocrine carcinoma of the paranasal sinuses is an extremely rare and aggressive neoplasm. Despite aggressive management, the tumor carries a poor prognosis, with a high risk of local recurrence or distant metastases. The management strategy is based on that for pulmonary small cell cancer and includes platinum-based chemotherapy combined with radiotherapy. We are reporting a case of an 89-year-old female patient diagnosed with small cell carcinoma of right-sided ethmoid and sphenoid sinuses. The tumor was found to have invaded the right orbit and anterior cranial fossa. Metastases to cervical lymph nodes and bone were also found. Due to the extended stage and poor prognosis of the patient, the management plan is palliative chemoradiotherapy.
authors: Presence Saint Joseph Hospital, Department of Internal Medicine, 2900 N. Lake Shore Drive, Chicago, IL 60657, USA.
authors: Maliha
authors: M
authors: Khan
authors: Department of Medicine, Aga Khan University, Karachi, Sindh 74800, Pakistan.
authors: Sobia
authors: S
authors: Nizami
authors: Presence Saint Joseph Hospital, Department of Internal Medicine, 2900 N. Lake Shore Drive, Chicago, IL 60657, USA.
authors: Aibek E
authors: AE
authors: Mirrakhimov
authors: Sidney Kimmel Comprehensive Cancer Center, John Hopkins University, Baltimore, MD 21287, USA.
authors: Benjamin
authors: B
authors: Maughan
authors: Sidney Kimmel Comprehensive Cancer Center, John Hopkins University, Baltimore, MD 21287, USA.
authors: Justin A
authors: JA
authors: Bishop
authors: Sidney Kimmel Comprehensive Cancer Center, John Hopkins University, Baltimore, MD 21287, USA.
authors: William H
authors: WH
authors: Sharfman