title: Neutrophilic Fixed Drug Eruption.
abstract: Fixed drug eruption (FDE) is a cutaneous reaction to a medication that recurs in the same fairly localized site with each exposure to the offending drug. The classical histopathologic findings in FDE consist of an interface dermatitis with predominantly lymphocytic inflammatory cell infiltrate. An unusual case of FDE in a 27-year-old pregnant woman who presented with widespread lesions and a predominantly neutrophilic infiltrate on histopathologic examination is reported.
authors: *Rush Medical College, Rush University, Chicago, IL; †Department of Surgery, Yale University Medical Center, New Haven, CT; ‡Department of Dermatology, Rush University Medical Center, Chicago, IL; and §Department of Pathology, Rush University Medical Center, Chicago, IL.
authors: Leah
authors: L
authors: Waldman
authors: Swathi B
authors: SB
authors: Reddy
authors: Andrea
authors: A
authors: Kassim
authors: Jennifer
authors: J
authors: Dettloff
authors: Vijaya B
authors: VB
authors: Reddy
mesh_terms: D000328:Adult; D000890:Anti-Infective Agents / Q000009:adverse effects; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D000935:Antifungal Agents / Q000009:adverse effects; D003875:Drug Eruptions / Q000209:etiology / Q000473:pathology*; D005260:Female; D015725:Fluconazole / Q000009:adverse effects; D006801:Humans; D008795:Metronidazole / Q000009:adverse effects; D009288:Naproxen / Q000009:adverse effects; D009504:Neutrophils / Q000473:pathology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000139:chemically induced / Q000473:pathology*
chemical_list: D000890:Anti-Infective Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000935:Antifungal Agents; D008795:Metronidazole; D009288:Naproxen; D015725:Fluconazole