title: Effects of atmospheric pollutants (CO, O3, SO2) on the allergenicity of Betula pendula, Ostrya carpinifolia, and Carpinus betulus pollen.
abstract: Pollen of Betula pendula, Ostrya carpinifolia, and Carpinus betulus was exposed in vitro to relatively low levels of the air pollutants, namely carbon monoxide, ozone, and sulfur dioxide. The allergenicity of the exposed pollen was compared with that of non-exposed pollen samples to assess if air pollution exposition affects the allergenicity potential of pollen. The immunodetection assays indicated higher IgE recognition by all sera of allergic patients to the pollen protein extracts in all exposed samples in comparison to the non-exposed samples. These results show that the pollen exposition to low pollutants' levels induces increased allergic reaction to sensitized individuals.
authors: a Centro de Investigação em Química (CIQ-UP), Departamento de Química e Bioquímica, Faculdade de Ciências , Universidade do Porto , Porto , Portugal.
authors: Lázaro G
authors: LG
authors: Cuinica
authors: Ana
authors: A
authors: Cruz
authors: Ilda
authors: I
authors: Abreu
authors: Joaquim C G Esteves
authors: JC
authors: da Silva
mesh_terms: D000393:Air Pollutants / Q000494:pharmacology; D000818:Animals; D029662:Betula / Q000187:drug effects / Q000276:immunology; D029401:Betulaceae / Q000187:drug effects / Q000276:immunology*; D002248:Carbon Monoxide / Q000494:pharmacology*; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007106:Immune Sera; D007073:Immunoglobulin E / Q000276:immunology / Q000378:metabolism; D051379:Mice; D010126:Ozone / Q000494:pharmacology*; D010940:Plant Proteins / Q000032:analysis / Q000276:immunology; D011058:Pollen / Q000187:drug effects / Q000276:immunology*; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology*; D013458:Sulfur Dioxide / Q000494:pharmacology*
chemical_list: D000393:Air Pollutants; D007106:Immune Sera; D010940:Plant Proteins; D013458:Sulfur Dioxide; D007073:Immunoglobulin E; D010126:Ozone; D002248:Carbon Monoxide
keywords: Betula pendula pollen; Carpinus betulus pollen; Ostrya carpinifolia pollen; air pollutants; allergic sensitization; pollen allergy