title: Matrix metalloproteinases and peripheral arterial disease.
abstract: It has been postulated that atherosclerosis should be considered as a chronic inflammatory process and peripheral arterial disease (PAD) is a manifestation of such an atherosclerotic vascular disease. Matrix metalloproteinases (MMPs) are significant circulating biomarkers which play a pivotal role in the initiation, progression and clinical manifestations of PAD. This review summarizes the current body of evidence with regard to the association between MMPs and PAD.
authors: Fifth Surgical Department, Hippokrateio General Hospital, Thessaloniki, Greece - kimisnet@gmail.com.
authors: I
authors: I
authors: Giagtzidis
authors: C
authors: C
authors: Karkos
authors: G
authors: G
authors: Pitoulias
authors: K
authors: K
authors: Papazoglou
mesh_terms: D000800:Angioplasty, Balloon; D000818:Animals; D015415:Biomarkers; D015897:Comorbidity; D003920:Diabetes Mellitus / Q000201:enzymology; D018450:Disease Progression; D005109:Extracellular Matrix / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000201:enzymology; D020782:Matrix Metalloproteinases / Q000378:metabolism*; D058729:Peripheral Arterial Disease / Q000150:complications* / Q000201:enzymology*; D051436:Renal Insufficiency, Chronic / Q000201:enzymology
chemical_list: D015415:Biomarkers; D020782:Matrix Metalloproteinases