title: Compositional studies and Biological activities of Perovskia abrotanoides Kar. oils.
abstract: BACKGROUND
  Current study has been designed to evaluate the chemical composition of essential and fixed oils from stem and leaves of Perovskia abrotanoides and antioxidant and antimicrobial activities of these oils.
  
  
  RESULTS
  GC-MS analysis of essential oil identified 19 compounds with (E)-9-dodecenal being the major component in stem and hexadecanoic acid in leaves. In contrast, GC-MS analysis of fixed oil showed 40 constituents with α-amyrin the major component in stem and α-copaene in leaves. The antioxidant activity showed the highest value of 76.7% in essential oil from leaves in comparison with fixed oil from stem (45.9%) through inhibition of peroxidation in linoleic acid system. The antimicrobial assay tested on different microorganisms (e.g. E. coli, S. aureus, B. cereus, Nitrospira, S. epidermis, A. niger, A. flavus and C. albicans) showed the higher inhibition zone at essential oil from leaves (15.2 mm on B. cereus) as compared to fixed oil from stem (8.34 mm on S. aureus) and leaves (11.2 mm on S. aureus).
  
  
  CONCLUSIONS
  The present study revealed the fact that essential oil analyzed from Perovskia abrotanoides stem and leaves could be a promising source of natural products with potential antioxidant and antimicrobial activities, as compared to fixed oil.
authors: Sadaf Naz
authors: SN
authors: Ashraf
authors: Muhammad
authors: M
authors: Zubair
authors: Komal
authors: K
authors: Rizwan
authors: Rasool Bakhsh
authors: RB
authors: Tareen
authors: Nasir
authors: N
authors: Rasool
authors: Muhammad
authors: M
authors: Zia-Ul-Haq
authors: Sezai
authors: S
authors: Ercisli
mesh_terms: D000473:Alkanes / Q000032:analysis / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology; D001230:Aspergillus / Q000187:drug effects; D001409:Bacillus cereus / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D052978:Disk Diffusion Antimicrobial Tests; D004926:Escherichia coli / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D019686:Lamiaceae / Q000737:chemistry*; D015227:Lipid Peroxidation / Q000187:drug effects; D008738:Methyl Ethers / Q000032:analysis / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry; D009828:Oleanolic Acid / Q000031:analogs & derivatives / Q000032:analysis / Q000494:pharmacology; D019308:Palmitic Acid / Q000032:analysis / Q000494:pharmacology; D053978:Pentacyclic Triterpenes / Q000032:analysis / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry*; D010938:Plant Oils / Q000737:chemistry / Q000494:pharmacology*; D018547:Plant Stems / Q000737:chemistry*; D019163:Reducing Agents / Q000032:analysis; D012717:Sesquiterpenes / Q000032:analysis / Q000494:pharmacology; D013210:Staphylococcus / Q000187:drug effects; D013229:Stearic Acids / Q000032:analysis / Q000494:pharmacology; D000094042:Lupanes
chemical_list: D000473:Alkanes; D000890:Anti-Infective Agents; D000975:Antioxidants; D008738:Methyl Ethers; D009822:Oils, Volatile; D009828:Oleanolic Acid; D019308:Palmitic Acid; D053978:Pentacyclic Triterpenes; D010938:Plant Oils; D019163:Reducing Agents; D012717:Sesquiterpenes; D013229:Stearic Acids; C024713:n-tetradecane; C050821:eicosane; C031183:stearic acid; C036380:beta-amyrin; C010480:lupeol; D000094042:Lupanes