title: First identification of a chromosomally located penicillinase gene in Kingella kingae species isolated in continental Europe.
abstract: Kingella kingae is the major pathogen causing osteoarticular infections (OAI) in young children in numerous countries. Plasmid-borne TEM-1 penicillinase production has been sporadically detected in a few countries but not in continental Europe, despite a high prevalence of K. kingae infections. We describe here for the first time a K. kingae β-lactamase-producing strain in continental Europe and demonstrate the novel chromosomal location of the blaTEM-1 gene in K. kingae species.
authors: INSERM, IAME, UMR 1137, Paris, France Université Paris Diderot, Sorbonne Paris Cité, IAME, UMR 1137, Paris, France AP-HP, Laboratoire de Microbiologie, Hôpital Robert-Debré, Paris, France.
authors: Romain
authors: R
authors: Basmaci
authors: INSERM, IAME, UMR 1137, Paris, France Université Paris Diderot, Sorbonne Paris Cité, IAME, UMR 1137, Paris, France AP-HP, Laboratoire de Microbiologie, Hôpital Robert-Debré, Paris, France.
authors: Philippe
authors: P
authors: Bidet
authors: INSERM, IAME, UMR 1137, Paris, France Université Paris Diderot, Sorbonne Paris Cité, IAME, UMR 1137, Paris, France AP-HP, Laboratoire de Bactériologie, Hôpital Lariboisière, Paris, France.
authors: Béatrice
authors: B
authors: Berçot
authors: INSERM, IAME, UMR 1137, Paris, France Université Paris Diderot, Sorbonne Paris Cité, IAME, UMR 1137, Paris, France AP-HP, Laboratoire de Microbiologie, Hôpital Robert-Debré, Paris, France.
authors: Christelle
authors: C
authors: Jost
authors: AP-HP, Service de Néphrologie Pédiatrique, Hôpital Robert-Debré, Paris, France.
authors: Thérésa
authors: T
authors: Kwon
authors: AP-HP, Service de Chirurgie Orthopédique Pédiatrique, Hôpital Robert-Debré, Paris, France.
authors: Elodie
authors: E
authors: Gaumetou
authors: INSERM, IAME, UMR 1137, Paris, France Université Paris Diderot, Sorbonne Paris Cité, IAME, UMR 1137, Paris, France AP-HP, Laboratoire de Microbiologie, Hôpital Robert-Debré, Paris, France stephane.bonacorsi@rdb.aphp.fr.
authors: Stéphane
authors: S
authors: Bonacorsi
mesh_terms: D016521:Electrophoresis, Gel, Pulsed-Field; D005060:Europe; D006801:Humans; D017882:Kingella kingae / Q000201:enzymology* / Q000235:genetics; D010405:Penicillinase / Q000235:genetics*
chemical_list: D010405:Penicillinase