title: Determination of buprenorphine by differential pulse voltammetry on carbon paste electrode using SDS as an enhancement factor.
abstract: In the present study, a facile electrochemical approach is proposed for the determination of buprenorphine (BPR) in the presence of sodium dodecyl sulfate (SDS). SDS was applied for amplification of oxidation signal. Carbon paste electrode (CPE) used as working electrode and cyclic voltammetry (CV), differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS) were carried out in phosphate buffer solution (pH3.0). Under optimal experimental conditions, the oxidation current increased with the addition of BPR in the sample and two dynamic ranges obtained from 4.00 nM to 0.126 μM and from 0.126 to 0.317 μM by DPV and exhibited a low detection limit (LOD) of 1.33 nM (S/N=3). This offered method has been used for the determination of BPR in the real samples and has validated with the recovery test for BPR spiked urine samples. The result demonstrated that this method is a simple, sensitive, rapid, low-cost, and stable method for BPR detection.
authors: Department of Analytical Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran. Electronic address: m.behpour@kashanu.ac.ir.
authors: Mohsen
authors: M
authors: Behpour
authors: Department of Analytical Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran.
authors: Akram
authors: A
authors: Valipour
authors: Department of Analytical Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran.
authors: Mahin
authors: M
authors: Keshavarz
mesh_terms: D002047:Buprenorphine / Q000032:analysis* / Q000737:chemistry / Q000652:urine; D002244:Carbon; D055664:Electrochemical Techniques / Q000295:instrumentation* / Q000379:methods*; D004566:Electrodes; D006801:Humans; D057230:Limit of Detection; D012967:Sodium Dodecyl Sulfate / Q000737:chemistry*
chemical_list: D012967:Sodium Dodecyl Sulfate; D002047:Buprenorphine; D002244:Carbon
keywords: Buprenorphine; Carbon paste electrode; Differential pulse voltammetry; Sodium dodecyl sulfate