title: The revolution of whole genome sequencing to study parasites.
abstract: Genome sequencing has revolutionized the way in which we approach biological research from fundamental molecular biology to ecology and epidemiology. In the last 10 years the field of genomics has changed enormously as technology has improved and the tools for genomic sequencing have moved out of a few dedicated centers and now can be performed on bench-top instruments. In this review we will cover some of the key discoveries that were catalyzed by some of the first genome projects and discuss how this field is developing, what the new challenges are and how this may impact on research in the near future.
authors.affiliation: Department of Comparative and Functional Genomics, University of Liverpool, Crown Street, Liverpool L69 7ZB, United Kingdom. Electronic address: S.J.Forrester@student.liverpool.ac.uk.
authors.forename: Sarah Jayne
authors.initials: SJ
authors.lastname: Forrester
authors.affiliation: Department of Comparative and Functional Genomics, University of Liverpool, Crown Street, Liverpool L69 7ZB, United Kingdom. Electronic address: Neil.Hall@liverpool.ac.uk.
authors.forename: Neil
authors.initials: N
authors.lastname: Hall
mesh_terms: D000818:Animals; D016678:Genome; D023281:Genomics; D010271:Parasites / Q000235:genetics*; D017422:Sequence Analysis, DNA / Q000639:trends*
keywords: Antigenic variation; Comparative genomics; Drug target; Genome sequencing; Genome structure