title: Bioresorbable scaffolds for the treatment of coronary artery disease: current status and future perspective.
abstract: Bioresorbable scaffolds represent a novel approach in the treatment of coronary artery disease which allows for vessel wall support without leaving a permanent foreign body in the coronary artery. This technology has the potential to reduce some of the shortcomings of current standard treatment with metallic drug-eluting stents, such as late in-stent restenosis, impaired vasomotion of the stented segment and hindrance of surgical revascularizations. Currently, several bioresorbable scaffolds are available and undergoing clinical or preclinical evaluation. This review will present the current status of development of bioresorbable scaffolds, describe the degradation/resorption process of each device and the clinical data available to date.
authors.affiliation: AMC Heartcenter, Academic Medical Center - University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
authors.forename: Robin P
authors.initials: RP
authors.lastname: Kraak
authors.forename: Maik J
authors.initials: MJ
authors.lastname: Grundeken
authors.forename: Karel T
authors.initials: KT
authors.lastname: Koch
authors.forename: Robbert J
authors.initials: RJ
authors.lastname: de Winter
authors.forename: Joanna J
authors.initials: JJ
authors.lastname: Wykrzykowska
mesh_terms: D020341:Absorbable Implants; D003324:Coronary Artery Disease / Q000601:surgery*; D054855:Drug-Eluting Stents; D005547:Foreign Bodies; D006801:Humans; D009204:Myocardial Revascularization / Q000295:instrumentation* / Q000379:methods
keywords: biodegradable; bioresorbable scaffold; coronary artery disease; drug-eluting stents; percutaneous coronary interventions