title: Intracranial cystic lesions: a review.
abstract: Cysts and cystic-appearing intracranial lesions are common findings with routine cerebral imaging examination. These lesions often represent a challenge in diagnosis. Intracranial cystic lesions have wide pathologic and imaging spectra, of which some require an aggressive and tailored treatment, whereas many others remain asymptomatic and do not require follow-up or intervention. Intracranial cysts can be divided in non-neoplastic lesions that are often of developmental origin but comprise as well infectious cysts and neoplastic lesions that include benign cysts associated with low-grade tumors and cysts as a component of higher grade neoplasms. Reviewed are the pathology, origin, radiologic appearance, differential diagnosis, and therapeutic aspects of intracranial cystic lesions.
authors.affiliation: Pitié-Salpétrière Hospital, Neurology Mazarin and Radiation Oncology Departments, Paris, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Taillibert
authors.forename: Emilie
authors.initials: E
authors.lastname: Le Rhun
authors.forename: Marc C
authors.initials: MC
authors.lastname: Chamberlain
mesh_terms: D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D003560:Cysts / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D014057:Tomography, X-Ray Computed
references.citation: AJNR Am J Neuroradiol. 2009 Mar;30(3):581-5
references.pmid: 18842767
references.citation: Pediatr Neurosurg. 1994;20(3):169-77
references.pmid: 8204490
references.citation: Acad Radiol. 2012 Jul;19(7):794-800
references.pmid: 22513110
references.citation: AJNR Am J Neuroradiol. 2000 Mar;21(3):485-8
references.pmid: 10730639
references.citation: J Neurooncol. 2008 Oct;90(1):25-30
references.pmid: 18566748
references.citation: J Clin Oncol. 2005 Mar 1;23(7):1491-9
references.pmid: 15735125
references.citation: Cancer. 2010 Dec 15;116(24):5725-32
references.pmid: 20737418
references.citation: J Clin Oncol. 2013 Apr 1;31(10):e159-60
references.pmid: 23358987
references.citation: Cancer. 2013 Dec 1;119(23):4180-7
references.pmid: 24104527
references.citation: Acta Neuropathol. 2013 Jun;125(6):891-900
references.pmid: 23435618
references.citation: J Clin Oncol. 2006 Apr 1;24(10):1554-60
references.pmid: 16575007
references.citation: Radiology. 2006 Jun;239(3):650-64
references.pmid: 16714456
references.citation: J Comput Assist Tomogr. 2004 Jul-Aug;28(4):540-7
references.pmid: 15232388
references.citation: J Neurooncol. 2005 Sep;74(2):187-94
references.pmid: 16193391
references.citation: Int J Radiat Oncol Biol Phys. 2013 Mar 1;85(3):667-71
references.pmid: 22885145
references.citation: Blood. 1998 Nov 1;92(9):3388-93
references.pmid: 9787178
references.citation: Curr Pain Headache Rep. 2004 Aug;8(4):297-300
references.pmid: 15228889
references.citation: J Neurosurg. 1989 Jan;70(1):24-30
references.pmid: 2909683
references.citation: Cancer Res. 2008 Nov 1;68(21):8673-7
references.pmid: 18974108
references.citation: Brain Tumor Pathol. 2006 Apr;23(1):29-34
references.pmid: 18095116
references.citation: N Engl J Med. 2009 Sep 17;361(12):1173-8
references.pmid: 19726761
references.citation: J Clin Oncol. 2005 Oct 20;23(30):7621-31
references.pmid: 16234523
references.citation: J Clin Oncol. 2009 Jan 20;27(3):385-9
references.pmid: 19064966
references.citation: Clin Neuropathol. 2002 May-Jun;21(3):93-8
references.pmid: 12049182
references.citation: Cancer. 2012 Sep 1;118(17):4212-9
references.pmid: 22213196
references.citation: J Neurosurg. 2002 Oct;97(4):977-82
references.pmid: 12405390
references.citation: Neurosurgery. 1991 Dec;29(6):893-7; discussion 897-8
references.pmid: 1758603
references.citation: Am J Med. 1961 Aug;31:318-24
references.pmid: 13782653
references.citation: J Clin Oncol. 2011 Apr 10;29(11):1408-14
references.pmid: 20823417
references.citation: Am J Trop Med Hyg. 2009 Mar;80(3):373-8
references.pmid: 19270284
references.citation: Med Hypotheses. 2006;66(4):801-4
references.pmid: 16321475
references.citation: Neurosurg Clin N Am. 1990 Jan;1(1):123-38
references.pmid: 2135964
references.citation: J Clin Oncol. 2011 Apr 10;29(11):1400-7
references.pmid: 20921458
references.citation: J Clin Oncol. 2010 Mar 10;28(8):1345-50
references.pmid: 20142599
references.citation: Brain Pathol. 2011 Sep;21(5):564-74
references.pmid: 21314850
references.citation: Acta Neuropathol. 2014 Aug;128(2):279-89
references.pmid: 24337497
references.citation: Surg Neurol. 1976 Apr;5(4):246-52
references.pmid: 1265637
references.citation: J Neurosurg. 2005 Apr;102(3 Suppl):314-7
references.pmid: 15881758
references.citation: Lancet Neurol. 2008 Dec;7(12):1099-105
references.pmid: 18986841
references.citation: J Clin Oncol. 2004 Sep 1;22(17):3639-40
references.pmid: 15337812
references.citation: J Clin Oncol. 2010 Nov 20;28(33):4961-8
references.pmid: 20940197
references.citation: J Clin Oncol. 2014 Mar 20;32(9):886-96
references.pmid: 24493713
references.citation: J Clin Oncol. 1995 Jul;13(7):1687-96
references.pmid: 7602359
references.citation: Neurology. 2013 Apr 9;80(15):1424-9
references.pmid: 23568997
references.citation: J Neurosurg. 2012 Dec;117 Suppl:17-22
references.pmid: 23205784
references.citation: Pediatr Neurosurg. 2001 Jun;34(6):306-10
references.pmid: 11455231
references.citation: J Neurosurg. 2003 Jan;98(1):95-105
references.pmid: 12546357
references.citation: Cancer. 2005 Jul 1;104(1):135-42
references.pmid: 15880432
references.citation: Pediatr Blood Cancer. 2011 Jan;56(1):7-15
references.pmid: 21108436
references.citation: J Neurosurg. 1996 Jul;85(1):56-65
references.pmid: 8683283
references.citation: Nature. 1998 Jul 9;394(6689):203-6
references.pmid: 9671307
references.citation: J Neurosurg. 2012 Dec;117 Suppl:45-8
references.pmid: 23205788
references.citation: Surg Neurol. 2006 Sep;66(3):246-50; discussion 250-1
references.pmid: 16935625
references.citation: Acta Neuropathol. 2011 Mar;121(3):397-405
references.pmid: 21274720
references.citation: J Neurooncol. 2009 Dec;95(3):377-382
references.pmid: 19533024
references.citation: Brain Pathol. 1993 Jul;3(3):297-306
references.pmid: 8293189
references.citation: Cancer. 1993 Aug 15;72(4):1335-42
references.pmid: 8339223
references.citation: J Neurol Neurosurg Psychiatry. 2001 May;70(5):644-8
references.pmid: 11309459
references.citation: Cancer. 2000 May 1;88(9):2189-93
references.pmid: 10813733
references.citation: Folia Neuropathol. 1995;33(1):41-50
references.pmid: 8673419
references.citation: J Neurosurg. 2006 Dec;105 Suppl:79-81
references.pmid: 18503335
references.citation: Cancer Res. 2011 Aug 1;71(15):5057-61
references.pmid: 21771911
references.citation: J Neurosurg. 2013 Feb;118(2):222-31
references.pmid: 23140149
references.citation: J Neurooncol. 2011 May;102(3):459-69
references.pmid: 21308398
references.citation: Surg Neurol. 2002 Jun;57(6):391-8; discussion 398
references.pmid: 12176198
references.citation: AJNR Am J Neuroradiol. 1996 Mar;17(3):525-31
references.pmid: 8881249
references.citation: J Neurosurg. 2011 Oct;115(4):754-9
references.pmid: 21761969
references.citation: Int J Radiat Oncol Biol Phys. 2007 Dec 1;69(5):1521-6
references.pmid: 17869023
references.citation: Otol Neurotol. 2002 Jan;23(1):84-92
references.pmid: 11773853
references.citation: Pediatr Blood Cancer. 2011 Jul 1;56(7):1026-31
references.pmid: 20848638
references.citation: J Pediatr Hematol Oncol. 2009 Sep;31(9):651-63
references.pmid: 19707161
references.citation: Neurology. 2012 Aug 21;79(8):793-6
references.pmid: 22875085
references.citation: Acta Neurochir Suppl. 1995;64:59-63
references.pmid: 8748585
references.citation: J Neurosurg. 2004 Jan;100(1):61-7
references.pmid: 14743913
references.citation: Neurosurgery. 2009 Jul;65(1):79-85; discussion 85
references.pmid: 19574828
references.citation: Acta Neurochir (Wien). 1998;140(11):1191-6
references.pmid: 9870067
references.citation: Lancet. 2003 Aug 16;362(9383):547-56
references.pmid: 12932389
references.citation: Acta Neurochir (Wien). 2000;142(1):97-100
references.pmid: 10664382
references.citation: J Clin Oncol. 2010 Dec 10;28(35):5188-96
references.pmid: 21060032
references.citation: Neuro Oncol. 2011 Feb;13(2):223-34
references.pmid: 21177781
references.citation: J Clin Oncol. 2011 Apr 10;29(11):1424-30
references.pmid: 21098324
references.citation: Magn Reson Imaging. 2009 Apr;27(3):434-40
references.pmid: 18789624
references.citation: AJNR Am J Neuroradiol. 2006 Jun-Jul;27(6):1362-9
references.pmid: 16775298
references.citation: J Neurooncol. 2005 Jan;71(1):33-8
references.pmid: 15719272
references.citation: Cancer. 2007 Nov 15;110(10):2276-84
references.pmid: 17926332
references.citation: Neurol India. 2004 Dec;52(4):524-5
references.pmid: 15626865
references.citation: Int J Radiat Oncol Biol Phys. 2013 May 1;86(1):114-20
references.pmid: 23498870