title: Hemophagocytic lymphohistiocytosis secondary to Mycoplasma pneumoniae infection without pneumonia.
abstract: Mycoplasma pneumoniae typically causes respiratory tract infections, including pneumonia. We herein report the case of a 30-year-old Japanese woman with hemophagocytic lymphohistiocytosis (HLH), which is rarely caused by bacteria, secondary to Mycoplasma pneumoniae infection and ensuing hypercytokinemia without pneumonia who was successfully treated with a combination of antibiotics and corticosteroids. Therefore, Mycoplasma pneumoniae infection, which is treatable with antibiotics, should be considered a possible trigger of HLH in patients who present with a viral-like illness without pneumonia.
authors.affiliation: Department of Respiratory Medicine, Shonan Fujisawa Tokushukai Hospital, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Hibino
authors.forename: Shuku
authors.initials: S
authors.lastname: Sato
authors.forename: Takanori
authors.initials: T
authors.lastname: Shimizu
authors.forename: Saori
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Motoki
authors.initials: M
authors.lastname: Ohe
authors.forename: Tetsuri
authors.initials: T
authors.lastname: Kondo
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001707:Biopsy, Needle; D001853:Bone Marrow / Q000473:pathology; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D009175:Mycoplasma Infections / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D009177:Mycoplasma pneumoniae / Q000302:isolation & purification*; D011014:Pneumonia; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents; D005938:Glucocorticoids