title: A cuff & a clock.
abstract: Ischemic conditioning is a unique physiologic process that has shown potential for reducing the size of MI in animal studies for more than twenty years. Early human trials have been inconclusive. However, one clinical trial is in progress that is well designed and will enroll enough subjects to potentially demonstrate significant reductions in mortality and hospitalization for congestive heart failure in STEMI patients who receive RIC in the field. Certainly, the simplicity, low cost and safety of ischemic conditioning merit continued clinical study in humans.
authors.forename: Terence
authors.initials: T
authors.lastname: Valenzuela
mesh_terms: D004562:Electrocardiography; D004638:Emergency Treatment / Q000379:methods*; D006801:Humans; D019157:Ischemic Preconditioning, Myocardial / Q000379:methods*; D009203:Myocardial Infarction / Q000503:physiopathology / Q000628:therapy*; D015428:Myocardial Reperfusion Injury / Q000503:physiopathology / Q000628:therapy*; D019722:Sphygmomanometers; D013997:Time Factors