title: Alternative therapies in management of leiomyomas.
abstract: Leiomyomas are benign soft-tissue neoplasms that arise from smooth muscle. Relief of symptoms (abnormal uterine bleeding, pain, pressure) is the major goal in management of women with significant symptoms. For symptomatic myomas, hysterectomy is a definitive solution; however, there are emerging less-invasive options. Magnetic resonance imaging-guided focused ultrasound surgery, cryomyolysis, and temporary occlusion of the uterine arteries are treatment options that are minimally invasive interventions with the benefit of preserving the uterus. This review summarizes procedure techniques, eligibility, complications, and outcomes of these alternate therapies.
authors.affiliation: Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
authors.forename: Amrita
authors.initials: A
authors.lastname: Patel
authors.affiliation: Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
authors.forename: Minnie
authors.initials: M
authors.lastname: Malik
authors.affiliation: Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
authors.forename: Joy
authors.initials: J
authors.lastname: Britten
authors.affiliation: Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, Maryland; Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
authors.forename: Jeris
authors.initials: J
authors.lastname: Cox
authors.affiliation: Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, Maryland; Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland. Electronic address: william.catherino@usuhs.edu.
authors.forename: William H
authors.initials: WH
authors.lastname: Catherino
mesh_terms: D000529:Complementary Therapies; D017679:Cryotherapy / Q000379:methods; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000379:methods; D007889:Leiomyoma / Q000601:surgery*; D053783:Magnetic Resonance Imaging, Interventional; D018084:Ultrasonography, Interventional / Q000379:methods; D055357:Uterine Artery Embolization; D014594:Uterine Neoplasms / Q000601:surgery*; D014599:Uterus / Q000601:surgery*
keywords: Leiomyomas; MRgFUS; cryomyolyisis; occlusion of uterine arteries