title: Computer-assisted cognitive-behavioral therapy for adolescent depression in primary care clinics in Santiago, Chile (YPSA-M): study protocol for a randomized controlled trial.
abstract: BACKGROUND
  Depression is a common and disabling condition. In Chile, assistance is guaranteed by law through a national program for depression in primary care services, and there is evidence of effective treatment for depressed women. However, there is a shortage of evidence-based treatments for depression in adolescents. The incorporation of technology to expand therapeutic options is becoming more common. This proposal aims to compare the efficacy of therapy that enhances traditional face-to-face cognitive-behavioral therapy (CBT) with a computer-based program versus usual care to treat depression in adolescents in primary care clinics in Santiago, Chile.
  
  
  METHODS
  This is a two-arm, single-blind, randomized controlled trial with a target enrollment of 216 depressed adolescents between 15 and 19 years of age, attending four primary care clinics in Santiago, Chile. In the active arm, depressed adolescents will receive eight sessions of computer-assisted CBT, led by trained psychologists on a weekly basis. In the control arm, depressed adolescents will receive treatment as usual from the primary care centers. Mean depression scores and indicators of dysfunctional thoughts, problem-solving strategies, and health-related quality of life will be measured at baseline and four and six months after randomization.
  
  
  CONCLUSIONS
  As far as we know, this is the first randomized controlled trial of a computer-assisted CBT intervention for depressed adolescents in a Latin American country.
  
  
  BACKGROUND
  Clinical Trials: NCT01862913.
authors.affiliation: Universidad de Chile, CEMERA, Facultad de Medicina, Profesor Zañartu 1030, Independencia, Santiago, Chile. vmartinezn@med.uchile.cl.
authors.forename: Vania
authors.initials: V
authors.lastname: Martínez
authors.forename: Pablo
authors.initials: P
authors.lastname: Martínez
authors.forename: Paul A
authors.initials: PA
authors.lastname: Vöhringer
authors.forename: Ricardo
authors.initials: R
authors.lastname: Araya
authors.forename: Graciela
authors.initials: G
authors.lastname: Rojas
mesh_terms: D000293:Adolescent; D000328:Adult; D002985:Clinical Protocols; D015928:Cognitive Behavioral Therapy; D003863:Depression / Q000628:therapy*; D006801:Humans; D017063:Outcome Assessment, Health Care; D011320:Primary Health Care; D012107:Research Design; D018401:Sample Size; D016037:Single-Blind Method; D013813:Therapy, Computer-Assisted
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