title: Redox-dependent conformational switching of diphenylacetylenes.
abstract: Herein we describe the design and synthesis of a redox-dependent single-molecule switch. Appending a ferrocene unit to a diphenylacetylene scaffold gives a redox-sensitive handle, which undergoes reversible one-electron oxidation, as demonstrated by cyclic voltammetry analysis. (1)H-NMR spectroscopy of the partially oxidized switch and control compounds suggests that oxidation to the ferrocenium cation induces a change in hydrogen bonding interactions that results in a conformational switch.
authors.affiliation: Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK. thoe.michaelos@yale.edu.
authors.forename: Ian M
authors.initials: IM
authors.lastname: Jones
authors.affiliation: Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK. peter.knipe@chem.ox.ac.uk.
authors.forename: Peter C
authors.initials: PC
authors.lastname: Knipe
authors.affiliation: Department of Chemistry, Yale University, P. O. Box 208107, New Haven, CT 06520-8107, USA. thoe.michaelos@yale.edu.
authors.forename: Thoe
authors.initials: T
authors.lastname: Michaelos
authors.affiliation: Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK. sam.thompson@chem.ox.ac.uk.
authors.forename: Sam
authors.initials: S
authors.lastname: Thompson
authors.affiliation: Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK. thoe.michaelos@yale.edu.
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Hamilton
mesh_terms: D000114:Acetylene / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D007477:Ions / Q000737:chemistry; D008958:Models, Molecular; D008968:Molecular Conformation; D019906:Nuclear Magnetic Resonance, Biomolecular; D010084:Oxidation-Reduction
chemical_list: D007477:Ions; C044735:biphenylacetylene; D000114:Acetylene
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