title: Effects of self-blood on the molding process of polymethyl methacrylate bone cement.
abstract: OBJECTIVE
  To evaluate whether the self-blood has influence on the molding process of polymethyl methacrylate (PMMA) bone cement, and to make sure whether it is valuable for the clinical practice.
  
  
  METHODS
  An in vitro study was performed to evaluate the prolonging-effect of self-blood on PMMA bone cement. The effect of prolonging was evaluated by the dough time (TD) and operable time (TO). Moreover, hardness test, squeezing value test and peak temperature test were also conducted to complete the evaluation of this program.
  
  
  RESULTS
  The self-blood, especially the plasma, could greatly prolong the handling time of PMMA bone cement without affecting its basic characteristics including hardness, leakage level and peak temperature. On the other hand, we found that in some abnormal conditions, for example with hyperlipemia, self-blood though can also prolong the handling time, would cause some side-effects.
  
  
  CONCLUSIONS
  We report a new effective way to prolong the handling time of PMMA bone cement by adding moderate amount of self-blood. But "individualized medicine" should be noticed because some abnormal conditions like hyperlipemia would cause undesired side-effects.
authors.affiliation: Department of Orthopaedic Surgery, Qilu Hospital of Shandong University, Jinan 250012, China.
authors.forename: Ying-Jun
authors.initials: YJ
authors.lastname: Guo
authors.forename: Lin
authors.initials: L
authors.lastname: Nie
authors.forename: Wen
authors.initials: W
authors.lastname: Zhang
authors.forename: Qing
authors.initials: Q
authors.lastname: Mu
mesh_terms: D001769:Blood; D001843:Bone Cements / Q000737:chemistry*; D006801:Humans; D066298:In Vitro Techniques; D008422:Materials Testing; D019904:Polymethyl Methacrylate / Q000737:chemistry*
chemical_list: D001843:Bone Cements; D019904:Polymethyl Methacrylate