title: Antimicrobial and antioxidant activities of a new benzamide from endophytic Streptomyces sp. YIM 67086.
abstract: A new benzamide (1) and four known compounds (2-5) were isolated from endophytic Streptomyces YIM67086, and their structures were determined as 2-amino-3,4-dihydroxy-5-methoxybenzamide (1), 4-hydroxy-3-methoxybenzoic acid (2), phenylacetic acid (3), N-acetyltyramine (4) and p-hydroxytruxinic acid (5). Compound 5 was first found in the microorganism. The antimicrobial activities of compounds 1-5 and antioxidant activity of compound 1 were investigated.
authors.affiliation: a Key Laboratory of Medicinal Chemistry for Natural Resource , Ministry of Education, School of Chemical Science and Technology, Yunnan University , Kunming 650091 , P.R. China.
authors.forename: Xueqiong
authors.initials: X
authors.lastname: Yang
authors.forename: Tianfeng
authors.initials: T
authors.lastname: Peng
authors.forename: Yabin
authors.initials: Y
authors.lastname: Yang
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Jie
authors.initials: J
authors.lastname: Xiong
authors.forename: Lixing
authors.initials: L
authors.lastname: Zhao
authors.forename: Zhongtao
authors.initials: Z
authors.lastname: Ding
mesh_terms: D000890:Anti-Infective Agents / Q000302:isolation & purification / Q000494:pharmacology*; D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology*; D001549:Benzamides / Q000302:isolation & purification / Q000494:pharmacology*; D060026:Endophytes / Q000737:chemistry; D015394:Molecular Structure; D013302:Streptomyces / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D000975:Antioxidants; D001549:Benzamides; C037689:benzamide
keywords: Streptomyces sp; antimicrobial activities; antioxidant activity; benzamide