title: [Metabolomics has the potential to improve drug therapy].
abstract: Until now drug therapy has primarily been controlled by dose titration on the basis of effects and side effects. However, a lot of people being treated with a drug experience too little effect or too many side effects. Therefore it will be advantageous to improve drug therapy and make it even more "individualized". In this chase metabolomics is a hot topic. The aim of this paper is to review the concepts of metabolomics and the possible applications in regard to drug development, drug therapy and diagnosis, prognosis and monitoring of diseases.
authors.affiliation: Klinisk Farmakologisk Afdeling, Bispebjerg Hospital, Bispebjerg Bakke 23, 2400 København NV. clausstage@hotmail.com.
authors.forename: Claus
authors.initials: C
authors.lastname: Stage
authors.forename: Gesche
authors.initials: G
authors.lastname: Jürgens
authors.forename: Kim Peder
authors.initials: KP
authors.lastname: Dalhoff
authors.forename: Henrik Berg
authors.initials: HB
authors.lastname: Rasmussen
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D004358:Drug Therapy / Q000379:methods / Q000639:trends; D006801:Humans; D055442:Metabolome; D055432:Metabolomics / Q000379:methods / Q000639:trends; D057285:Precision Medicine / Q000379:methods
chemical_list: D015415:Biomarkers