title: Redox-based selective fluorometric detection of homocysteine.
abstract: Plasma homocysteine (Hcy) is an important risk factor for various diseases. A novel redox-sensitive fluorescent probe is developed for the selective detection of Hcy. A linear calibration curve has been obtained in buffer and plasma for the quantitative determination of Hcy in such media.
authors.affiliation: Department of Chemistry and the Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30303, USA. wang@gsu.edu.
authors.forename: Hanjing
authors.initials: H
authors.lastname: Peng
authors.forename: Ke
authors.initials: K
authors.lastname: Wang
authors.forename: Chaofeng
authors.initials: C
authors.lastname: Dai
authors.forename: Samuel
authors.initials: S
authors.lastname: Williamson
authors.forename: Binghe
authors.initials: B
authors.lastname: Wang
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D000818:Animals; D001386:Azides / Q000138:chemical synthesis / Q000737:chemistry; D002417:Cattle; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry; D006710:Homocysteine / Q000032:analysis / Q000097:blood* / Q000737:chemistry; D010084:Oxidation-Reduction; D010710:Phosphates / Q000737:chemistry; D044967:Serum / Q000737:chemistry; D013050:Spectrometry, Fluorescence
chemical_list: D000596:Amino Acids; D001386:Azides; D005456:Fluorescent Dyes; D010710:Phosphates; D006710:Homocysteine; C018279:sodium phosphate