title: Dramatic regression of presumed acquired retinal astrocytoma with photodynamic therapy.
abstract: Photodynamic therapy (PDT) has been used for treatment of various intraocular tumors including choroidal hemangioma, vasoproliferative tumor, amelanotic choroidal melanoma and choroidal neovascular membrane due to choroidal osteoma. This case report documents the effect of PDT for a presumed acquired retinal astrocytoma. A 42-year-old female with a juxtapapillary acquired astrocytoma was treated with a single session of PDT using standard parameters. The tumor showed dramatic regression over 6 months into a fibrotic scar. It remained regressed and stable with 20/20 vision after 51 months of follow-up. We believe that PDT can be used as a primary treatment for acquired retinal astrocytoma.
authors.affiliation: Department of Ophthalmology, Istanbul Faculty of Medicine, Istanbul University, Capa 34390, Istanbul, Turkey.
authors.forename: Samuray
authors.initials: S
authors.lastname: Tuncer
authors.affiliation: Department of Ophthalmology, Istanbul Faculty of Medicine, Istanbul University, Capa 34390, Istanbul, Turkey.
authors.forename: Zafer
authors.initials: Z
authors.lastname: Cebeci
mesh_terms: D000328:Adult; D001254:Astrocytoma / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006801:Humans; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D011166:Porphyrins / Q000627:therapeutic use*; D019572:Retinal Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D041623:Tomography, Optical Coherence; D000077362:Verteporfin; D014792:Visual Acuity
chemical_list: D017319:Photosensitizing Agents; D011166:Porphyrins; D000077362:Verteporfin
keywords: Astrocytoma; Photodynamic Therapy; Retinal Astrocytoma
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