title: Immunohistochemical localization of androgen and progesterone receptors in the uterus of the camel (Camelus dromedarius).
abstract: Ten adult, cyclic female camels (Camelus dromedarius) were used to describe the distribution of androgen (AR) and progesterone (PR) receptors in the uterus using immunohistochemistry. Both AR and PR were distributed throughout the different compartments of the uterus with nuclear staining for AR and PR seen in the cells of epithelia (luminal and glandular), stroma and myometrial smooth muscles. AR immunostaining was not uniform in distribution and intensity; the surface epithelium and the glandular epithelium in the adluminal region of the endometrium showed lower AR immunoreactivity than other compartments of the uterus. PR immunostaining showed uniformity in both distribution and intensity strong PR immunostaining intensity in almost all cells of the different uterine compartments. The intensity and distribution of PR immunostaining in epithelia of lumen and glands in the adluminal regions of endometrium was higher (P<0.05) than that of AR. In conclusion, immunohistochemical localization of AR and PR in the uterus of the cyclic dromedary camel indicates the important roles of androgen and progesterone in controlling the uterine activity during the follicular phase.
authors.affiliation: Histology and Cytology Department, Faculty of Veterinary Medicine, Benha University, 13736 Egypt. Electronic address: mahmoud.hussein@fvtm.bu.edu.eg.
authors.forename: Mahmoud Abdelghaffar
authors.initials: MA
authors.lastname: Emam
mesh_terms: D000818:Animals; D002162:Camelus / Q000378:metabolism*; D005260:Female; D007150:Immunohistochemistry; D011944:Receptors, Androgen / Q000378:metabolism*; D011980:Receptors, Progesterone / Q000378:metabolism*; D014599:Uterus / Q000378:metabolism*
chemical_list: D011944:Receptors, Androgen; D011980:Receptors, Progesterone
keywords: Androgen receptor; Camel; Immunohistochemistry; Progesterone receptor; Uterus