title: The constituents of roots and stems of Illigera luzonensis and their anti-platelet aggregation effects.
abstract: Phytochemical investigation of the roots and stems of Illigera luzonensis afforded two new aporphine alkaloids (1) and (2), one new bisdehydroaporphine alkaloid (3), and one new benzenoid (4), along with 28 known structures. The structures of new compounds were elucidated by spectral and MS analysis. Among the isolated compounds, (1) and (4-13) were subjected into the examination for their inhibitory effects on the aggregation of washed rabbit platelets.
authors.affiliation: Department of Chemistry, National Cheng Kung University, Tainan 70101, Taiwan. hjh2000.tw@gmail.com.
authors.forename: Chieh-Hung
authors.initials: CH
authors.lastname: Huang
authors.affiliation: Department of Biotechnology, Southern Taiwan University of Technology, Tainan 71005, Taiwan. yuyichan@mail.stust.edu.tw.
authors.forename: Yu-Yi
authors.initials: YY
authors.lastname: Chan
authors.affiliation: Department of Biotechnology, National Formosa University, Yunlin 63201, Taiwan. pcckuoo@sunws.nfu.edu.tw.
authors.forename: Ping-Chung
authors.initials: PC
authors.lastname: Kuo
authors.affiliation: Department of Life Sciences, National Cheng Kung University, Tainan 70101, Taiwan. yufons@gmail.com.
authors.forename: Yu-Fon
authors.initials: YF
authors.lastname: Chen
authors.affiliation: Department of Chemistry, National Cheng Kung University, Tainan 70101, Taiwan. l3894116@mail.ncku.edu.tw.
authors.forename: Ren-Jie
authors.initials: RJ
authors.lastname: Chang
authors.affiliation: Department of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan. m635013@kmu.edu.tw.
authors.forename: Ih-Sheng
authors.initials: IS
authors.lastname: Chen
authors.affiliation: Department of Medical Laboratory Science and Biotechnology, Chung Hwa University of Medical Technology, Tainan 71703, Taiwan. shwu01054@yahoo.com.tw.
authors.forename: Shwu-Jen
authors.initials: SJ
authors.lastname: Wu
authors.affiliation: Department of Chemistry, National Cheng Kung University, Tainan 70101, Taiwan. tswu@mail.ncku.edu.tw.
authors.forename: Tian-Shung
authors.initials: TS
authors.lastname: Wu
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D001060:Aporphines / Q000737:chemistry; D049935:Hernandiaceae / Q000737:chemistry* / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry / Q000378:metabolism; D018547:Plant Stems / Q000737:chemistry / Q000378:metabolism; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology; D011817:Rabbits
chemical_list: D000470:Alkaloids; D001060:Aporphines; D010936:Plant Extracts; D010975:Platelet Aggregation Inhibitors; C081279:aporphine
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