title: [Microalbuminuria as a marker of endothelial dysfunction in the long-term follow-up patients after surgical correction of aortic coarctation].
abstract: 1170 patients after surgical correction of aortic coarctation during the period from 1988 to 2002 were studied. The median period of medical supervision after coarctation repair was 13,8 years, maximum age - 24 years. For diagnostics of the Microalbuminuria (MAU) it were used the special test-strings Microalbu PHAN (PLIVA-Lachema Diagnostica). MAU were discovered in 62.6% of and 34.9% of normotesive patients. Credible decrease of MAU of hypertensive patients with corrected coarctation of the aorta were defined after 3 months-long treatment by Losartan.
authors.forename: N I
authors.initials: NI
authors.lastname: Volkova
authors.forename: V V
authors.initials: VV
authors.lastname: Lazoryshynets
mesh_terms: D000293:Adolescent; D000328:Adult; D000419:Albuminuria / Q000150:complications / Q000188:drug therapy / Q000601:surgery / Q000652:urine*; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001013:Aorta, Thoracic / Q000187:drug effects / Q000473:pathology / Q000601:surgery; D001017:Aortic Coarctation / Q000150:complications / Q000188:drug therapy / Q000601:surgery / Q000652:urine*; D015415:Biomarkers / Q000652:urine; D002648:Child; D003404:Creatinine / Q000652:urine; D004730:Endothelium, Vascular / Q000378:metabolism* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy / Q000601:surgery / Q000652:urine*; D019808:Losartan / Q000627:therapeutic use; D008297:Male; D012189:Retrospective Studies
chemical_list: D000959:Antihypertensive Agents; D015415:Biomarkers; D003404:Creatinine; D019808:Losartan