title: Chemo-mechanical caries removal with Papacarie™: case series with 84 reports and 12 months of follow-up.
abstract: OBJECTIVE
  The aim of the present study was to determine the success rate after 12 months of follow-up in a series of cases in which chemo-mechanical caries removal (CMCR) was performed with Papacarie(TM), followed by restoration with glass ionomer cement.
  
  
  BACKGROUND
  The development of conservative techniques for carious tissue removal and improvements in dental restoration materials have allowed better preservation of dental structures in the treatment of decayed teeth. Chemo-mechanical caries removal (CMCR) is a conservative atraumatic treatment option. Papacarie(TM) is a papain-based material developed to act only on the carious dentin, allowing its easy removal with a blunt curette.
  
  
  METHODS
  The study involved a total of 84 deciduous posterior teeth with occlusal dentinal caries. Only teeth without risk of pulp exposure were studied. After a period of 12 months, the restorations were evaluated based on criteria employed in previous studies. The radiographic evaluation revealed resorption and calcification of the affected teeth. The data were submitted to descriptive statistical analysis with the aid of the XLSTAT program. The success rate was 88.1% and 98.8% based on the clinical and radiographic evaluations, respectively. The difference between the success and failure rates was statistically significant (p < 0.0001).
  
  
  CONCLUSIONS
  Papacarie(TM) is an effective product for CMCR on occlusal dentinal tissue in deciduous teeth, demonstrating a high clinical and radiographic success rate after 12 months of follow-up.
authors.affiliation: Professor, Department of Rehabilitation Sciences Postgraduation Program, Universidade Nove de Julho, Brazil.
authors.forename: Sandra Kalil
authors.initials: SK
authors.lastname: Bussadori
authors.affiliation: Student, Department of Rehabilitation Sciences Postgraduation Program, Universidade Nove de Julho, Brazil.
authors.forename: Camila Haddad Leal de
authors.initials: CH
authors.lastname: Godoy
authors.affiliation: Student, Department of Dental Clinic of Postgraduation Program Universidade Federal Fluminense, Brazil.
authors.forename: Thays Almeida
authors.initials: TA
authors.lastname: Alfaya
authors.affiliation: Professor, Department of Rehabilitation Sciences Postgraduation Program, Universidade Nove de Julho, Brazil.
authors.forename: Kristianne Porta Santos
authors.initials: KP
authors.lastname: Fernandes
authors.affiliation: Professor, Department of Rehabilitation Sciences Postgraduation Program, Universidade Nove de Julho, Brazil.
authors.forename: Raquel Agnelli
authors.initials: RA
authors.lastname: Mesquita-Ferrari
authors.affiliation: Professor, Department of Health Systems Management, Postgraduate Program, Universidade Nove de Julho, Brazil.
authors.forename: Lara Jansiski
authors.initials: LJ
authors.lastname: Motta
mesh_terms: D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D002675:Child, Preschool; D002710:Chlorhexidine / Q000031:analogs & derivatives / Q000627:therapeutic use; D003475:Curettage / Q000295:instrumentation; D057087:Dental Atraumatic Restorative Treatment / Q000379:methods; D003731:Dental Caries / Q000000981:diagnostic imaging / Q000628:therapy*; D003737:Dental Cavity Preparation / Q000295:instrumentation / Q000379:methods*; D003804:Dentin / Q000000981:diagnostic imaging / Q000473:pathology; D005500:Follow-Up Studies; D005899:Glass Ionomer Cements / Q000737:chemistry; D006801:Humans; D010206:Papain / Q000627:therapeutic use*; D011859:Radiography; D014089:Tooth Remineralization / Q000379:methods; D014094:Tooth, Deciduous / Q000000981:diagnostic imaging / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000891:Anti-Infective Agents, Local; D005899:Glass Ionomer Cements; C515713:Ketac Molar Easymix; C509557:Papacarie; D010206:Papain; C010882:chlorhexidine gluconate; D002710:Chlorhexidine