title: Compare mDCs and pDCs between two distinct patients groups in acute HIV-1 infection.
abstract: The role of DCs in primary HIV-1 infection remains uncertain. In this study, we enrolled two different groups of subjects with acute HIV-1 infection. One group progressed to CD4 counts below 200 cells/μl within 2 years of HIV-1 infection (CD4 Low Group), while the other group maintained CD4 counts above 500 cells/μl (CD4 High Group). We did not find statistical difference in the pDC number between the two groups during acute HIV-1 infection. However, the mDC number was significantly lower in the CD4 Low Group than in the CD4 High Group.
authors.affiliation: Center for Infectious Diseases, Beijing You-an Hospital, Capital Medical University, Beijing 100069, China.
authors.forename: Yanmei
authors.initials: Y
authors.lastname: Jiao
authors.affiliation: Center for Infectious Diseases, Beijing You-an Hospital, Capital Medical University, Beijing 100069, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Sun
authors.affiliation: Center for Infectious Diseases, Beijing You-an Hospital, Capital Medical University, Beijing 100069, China.
authors.forename: Xiaojie
authors.initials: X
authors.lastname: Huang
authors.affiliation: Center for Infectious Diseases, Beijing You-an Hospital, Capital Medical University, Beijing 100069, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.affiliation: Center for Infectious Diseases, Beijing You-an Hospital, Capital Medical University, Beijing 100069, China.
authors.forename: Tong
authors.initials: T
authors.lastname: Zhang
authors.affiliation: Center for Infectious Diseases, Beijing You-an Hospital, Capital Medical University, Beijing 100069, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Wu
keywords: Acute HIV-1 infection; DCs; Rapid disease progression
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