title: Corneal deposit after topical ciprofloxacin as postoperative medication after cataract surgery.
abstract: OBJECTIVE
  To report 5 cases of corneal deposits after administration of topical ciprofloxacin as postoperative medication after uneventful cataract surgery.
  
  
  METHODS
  Observational Case Series.
  
  
  METHODS
  Five patients ranging from 60 to 72 years of age.
  
  
  METHODS
  All cases were operated by small-incision cataract surgery technique and prescribed postoperatively ciprofloxacin and prednisolone acetate eye drops. All cases had corneal deposits on second follow-up visit (15 days after cataract surgery) with decreased visual acuity. Ciprofloxacin eye drops were immediately discontinued and replaced by topical artificial tear substitute and tobramycin eye drop along with prednisolone acetate. In 1 case, surgical debridement was done.
  
  
  RESULTS
  Complete resolution of corneal deposit occurred in 2 months with good recovery of visual acuity in cases managed conservatively. The case with surgical debridement required more time for healing and visual recovery.
  
  
  CONCLUSIONS
  More frequent and prolonged application of ciprofloxacin drops can lead to drug precipitation, which can interfere with surgical outcome.
authors.affiliation: Department of Ophthalmology, Tulsi Eye Hospital, Nashik, Maharashtra, India. Electronic address: swati_anuja@yahoo.com.
authors.forename: Swati
authors.initials: S
authors.lastname: Vijay Zawar
authors.affiliation: Department of Ophthalmology, Tulsi Eye Hospital, Nashik, Maharashtra, India.
authors.forename: Sanjay
authors.initials: S
authors.lastname: Mahadik
mesh_terms: D000287:Administration, Topical; D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D002387:Cataract Extraction; D011232:Chemical Precipitation; D002939:Ciprofloxacin / Q000009:adverse effects*; D003316:Corneal Diseases / Q000139:chemically induced* / Q000503:physiopathology; D009877:Endophthalmitis / Q000517:prevention & control; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D009883:Ophthalmic Solutions; D011182:Postoperative Care; D011239:Prednisolone / Q000031:analogs & derivatives / Q000627:therapeutic use; D014792:Visual Acuity
chemical_list: D000900:Anti-Bacterial Agents; D005938:Glucocorticoids; D009883:Ophthalmic Solutions; D002939:Ciprofloxacin; C009935:prednisolone acetate; D011239:Prednisolone