title: Granulosa cell tumor and concurrent endometrial cancer with (18)F-FDG uptake.
abstract: The findings and the role of fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) for the diagnosis of ovarian granulosa cell tumor (OG) are described. We present the pre-operative findings of (18)F-FDG PET/CT scan of a case of OG concurrent with endometrium cancer and endometrial hyperplasia, which revealed a 48mm mass demonstrating mild increased metabolic activity on the right ovary. Total abdominal hysterectomy and bilateral salpingo-oophorectomy was performed. Frozen and paraffin-enbeded sections showed an encapsulated OG. There were few mitoses. There was concurrent atypical endometrial hyperplasia. In conclusion, we reported a case of an encapsulated OG, which showed mild uptake of the (18)F-FDG with concurrent endometrial cancer. There has been only one report of (18)F-FDG findings in primary ovarian granulosa cell tumor, similar to ours.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Suleyman Demirel University, Isparta, 32000,Turkey. evrimmd@yahoo.com.
authors.forename: Ilker
authors.initials: I
authors.lastname: Günyeli
authors.forename: Kemal K
authors.initials: KK
authors.lastname: Bozkurt
authors.forename: Yakup
authors.initials: Y
authors.lastname: Yalçın
authors.forename: Burak
authors.initials: B
authors.lastname: Tatar
authors.forename: Sevim S
authors.initials: SS
authors.lastname: Cerçi
authors.forename: Evrim
authors.initials: E
authors.lastname: Erdemoğlu
mesh_terms: D000328:Adult; D001692:Biological Transport; D016889:Endometrial Neoplasms / Q000150:complications*; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism*; D006106:Granulosa Cell Tumor / Q000150:complications* / Q000175:diagnosis* / Q000378:metabolism; D006801:Humans; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18