title: Pseudo chediak-higashi granules in acute lymphoblastic leukemia: a rare entity.
abstract: Pseudo-Chediak-Highashi granules are giant cytoplasmic inclusions commonly encountered in myeloblasts or other myeloid precursors in acute myeloid leukemia and myelodysplastic syndromes. They derive their name from the inherited Chediak-Higashi syndrome that presents with oculocutaneous albinism, chronic infections and platelet dense granule deficiency. We report possibly the third case in world literature where these granules were seen in the blast cells of acute lymphoblastic leukemia in a 15-year-old male.
authors.affiliation: Department of Haematology, Level 5, Research Block A, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012 India.
authors.forename: Pallavi
authors.initials: P
authors.lastname: Agrawal
authors.affiliation: Department of Haematology, Level 5, Research Block A, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012 India.
authors.forename: Narender
authors.initials: N
authors.lastname: Kumar
authors.affiliation: Department of Haematology, Level 5, Research Block A, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012 India.
authors.forename: Prashant
authors.initials: P
authors.lastname: Sharma
authors.affiliation: Department of Internal Medicine, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012 India.
authors.forename: Subhash
authors.initials: S
authors.lastname: Varma
authors.affiliation: Department of Haematology, Level 5, Research Block A, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012 India.
authors.forename: Neelam
authors.initials: N
authors.lastname: Varma
keywords: Acute lymphoblastic leukemia; Bone marrow; Flow cytometry; Morphology; Pseudo Chediak-Highashi granules
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