title: Endoscopic cyclophotocoagulation combined with phacoemulsification versus phacoemulsification alone in medically controlled glaucoma.
abstract: OBJECTIVE
  To compare the outcomes of combined endoscopic cyclophotocoagulation (ECP) and phacoemulsification cataract extraction versus cataract extraction alone in eyes with medically controlled open-angle glaucoma (OAG) and visually significant cataract.
  
  
  METHODS
  Clinical practices of glaucoma specialists and comprehensive ophthalmologists.
  
  
  METHODS
  Prospective nonrandomized matched-control study.
  
  
  METHODS
  Consecutive patients with medically controlled OAG and visually significant cataracts were treated with ECP and cataract extraction (study group) or cataract extraction alone (control group). The groups were matched in age and baseline intraocular pressure (IOP). The main outcome measures were the change in IOP and number of glaucoma medications. Secondary measures included visual acuity and postoperative complications.
  
  
  RESULTS
  In the study group (n = 80) the mean IOP decreased (baseline: 18.1 mm Hg ± 3.0 [SD]; 1 year: 16.0 ± 2.8 mm Hg; 2 years: 16.0 ± 3.3 mm Hg). The number of glaucoma medications decreased from 1.5 ± 0.8 to 0.4 ± 0.7 (1 year and 2 years). In the control group (n = 80), the mean IOP was 18.1 ± 3.0 mm Hg (baseline), 17.5 ± 3.6 mm Hg (1 year), and 17.3 ± 3.2 mm Hg (2 years). The mean number of glaucoma medications was 2.4 ± 1.0, 1.8 ± 1.2, and 2.0 ± 1.0, respectively. The difference in IOP and medication reduction between the 2 groups was statistically significant at all timepoints. Visual acuity outcomes and complication rates were similar between the 2 groups.
  
  
  CONCLUSIONS
  Combined ECP and cataract extraction resulted in lower IOP and a greater reduction in glaucoma medications than cataract extraction alone in medically controlled OAG patients with visually significant cataract.
  
  
  BACKGROUND
  Proprietary or commercial disclosures are listed after the references.
authors.affiliation: From Doheny Eye Institute (Francis), Department of Ophthalmology, David Geffen School of Medicine of the University of California Los Angeles, and the Department of Preventative Medicine and Biostatistics (Dustin), Keck School of Medicine of the University of Southern California, Los Angeles, California; Albert Einstein College of Medicine, Bronx and Nassau University Medical Center (Berke), and East Meadow, the Ophthalmic Consultants of Long Island (Berke), Lynbrook, New York; Ophthalmic Consultants of Connecticut (Noecker), Fairfield, Connecticut, USA. Electronic address: francis@jsei.ucla.edu.
authors.forename: Brian A
authors.initials: BA
authors.lastname: Francis
authors.affiliation: From Doheny Eye Institute (Francis), Department of Ophthalmology, David Geffen School of Medicine of the University of California Los Angeles, and the Department of Preventative Medicine and Biostatistics (Dustin), Keck School of Medicine of the University of Southern California, Los Angeles, California; Albert Einstein College of Medicine, Bronx and Nassau University Medical Center (Berke), and East Meadow, the Ophthalmic Consultants of Long Island (Berke), Lynbrook, New York; Ophthalmic Consultants of Connecticut (Noecker), Fairfield, Connecticut, USA.
authors.forename: Stanley J
authors.initials: SJ
authors.lastname: Berke
authors.affiliation: From Doheny Eye Institute (Francis), Department of Ophthalmology, David Geffen School of Medicine of the University of California Los Angeles, and the Department of Preventative Medicine and Biostatistics (Dustin), Keck School of Medicine of the University of Southern California, Los Angeles, California; Albert Einstein College of Medicine, Bronx and Nassau University Medical Center (Berke), and East Meadow, the Ophthalmic Consultants of Long Island (Berke), Lynbrook, New York; Ophthalmic Consultants of Connecticut (Noecker), Fairfield, Connecticut, USA.
authors.forename: Laurie
authors.initials: L
authors.lastname: Dustin
authors.affiliation: From Doheny Eye Institute (Francis), Department of Ophthalmology, David Geffen School of Medicine of the University of California Los Angeles, and the Department of Preventative Medicine and Biostatistics (Dustin), Keck School of Medicine of the University of Southern California, Los Angeles, California; Albert Einstein College of Medicine, Bronx and Nassau University Medical Center (Berke), and East Meadow, the Ophthalmic Consultants of Long Island (Berke), Lynbrook, New York; Ophthalmic Consultants of Connecticut (Noecker), Fairfield, Connecticut, USA.
authors.forename: Robert
authors.initials: R
authors.lastname: Noecker
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000008:administration & dosage; D002386:Cataract / Q000150:complications*; D002924:Ciliary Body / Q000601:surgery*; D004724:Endoscopy; D005260:Female; D005902:Glaucoma, Open-Angle / Q000150:complications* / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D017075:Laser Coagulation; D054023:Lasers, Semiconductor / Q000627:therapeutic use; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011183:Postoperative Complications; D011446:Prospective Studies; D014065:Tonometry, Ocular; D014792:Visual Acuity / Q000502:physiology
chemical_list: D000959:Antihypertensive Agents