title: [Attitudes of pregnant Japanese women and folic acid intake for the prevention of neural tube defects: a nationwide Internet survey].
abstract: OBJECTIVE
  Folic acid intake is recommended for pregnant women because it significantly reduces the risk of neural tube defects (NTD) in the fetus. However, the risk of NTD remains medium in Japan. In this study, the attitudes of pregnant Japanese women and factors related to folic acid intake for the prevention of NTD were evaluated using a nationwide survey.
  
  
  METHODS
  An Internet-based questionnaire was conducted on 2,367 pregnant Japanese women who were registrants of a Japanese social research company in January 2012; 1,236 of these women responded. In the questionnaires, the knowledge regarding the folate intake (i.e., name of folic acid, the risk of NTD, recommended doses, and timing), actual intake of folic acid, demographic factors (i.e., age, geographical area, gestational age, and birth order), and intake of dietary supplements were surveyed.
  
  
  RESULTS
  Eighty-five percent of respondents consumed folate, which was mostly obtained through dietary folic acid supplements during the first month of pregnancy or after. Factors associated with loss of folic acid intake until 3 months of pregnancy included lack of knowledge, failure to consume dietary supplements, younger age, and multigravida.
  
  
  CONCLUSIONS
  Many pregnant women in Japan consumed folic acid. However, most of them started supplementation after pregnancy recognition, which is too late to reduce the risk of NTD. Alternative strategies to increase the efficacy of folic acid intake, such as recommending folic acid-enriched foods, promoting folic acid fortification efforts, and providing access to practical information, are necessary.
authors.affiliation: National Institute of Health and Nutrition.
authors.forename: Yoko
authors.initials: Y
authors.lastname: Sato
authors.forename: Tomoko
authors.initials: T
authors.lastname: Nakanishi
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Chiba
authors.forename: Keizo
authors.initials: K
authors.lastname: Umegaki
mesh_terms: D000328:Adult; D001294:Attitude to Health; D003625:Data Collection; D019587:Dietary Supplements; D005260:Female; D005492:Folic Acid / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D009436:Neural Tube Defects / Q000517:prevention & control*; D011247:Pregnancy; D012307:Risk Factors; D012923:Social Class; D055815:Young Adult
chemical_list: D005492:Folic Acid