title: Implications of vitamin D deficiency in lithiasic patient and in general population.
abstract: OBJECTIVE
  Vitamin D deficiency causes problems in mineral metabolism but also overall health. In first place a review of the topic was carried out. Then, in order to contextualize it in lithiasic patient, a study on Vitamin D deficiency and its possible relationship with impaired PTH levels is performed.
  
  
  METHODS
  A review of topics such as metabolism, epidemiology and the relationship of vitamin D deficiency with several pathologies was performed. Besides a multivariate analysis and a correlation study between vitamin D and PTH levels was conducted in 100 lithiasic patients.
  
  
  RESULTS
  We present a review of Vitamin D metabolism, receptors and functions, as well as about its valuation methodology and the treatment of its deficiency. Lithiasic patients show a higher vitamin D deficiency than general population. Vitamin D deficiency has been significantly associated with increased PTH levels. In addition, there is enough literature showing a relationship between vitamin D deficiency not only with bone disease, but also with multiple diseases.
  
  
  CONCLUSIONS
  vitamin D levels should be measured in all lithiasic patients, and those with vitamin D deficiency should be treated.
authors.affiliation: Servicio de Urología, Fundació Puigvert, Barcelona, España. Electronic address: fmillan@fundacio-puigvert.es.
authors.forename: F
authors.initials: F
authors.lastname: Millán-Rodríguez
authors.affiliation: Servicio de Urología, Fundació Puigvert, Barcelona, España.
authors.forename: P
authors.initials: P
authors.lastname: Gavrilov
authors.affiliation: Servicio de Bioquímica, Fundació Puigvert, Barcelona, España.
authors.forename: S
authors.initials: S
authors.lastname: Gracia-García
authors.affiliation: Servicio de Urología, Fundació Puigvert, Barcelona, España.
authors.forename: O
authors.initials: O
authors.lastname: Angerri-Feu
authors.affiliation: Servicio de Urología, Fundació Puigvert, Barcelona, España.
authors.forename: F M
authors.initials: FM
authors.lastname: Sánchez-Martín
authors.affiliation: Servicio de Urología, Fundació Puigvert, Barcelona, España.
authors.forename: H
authors.initials: H
authors.lastname: Villavicencio-Mavrich
mesh_terms: D001842:Bone and Bones / Q000378:metabolism; D002118:Calcium / Q000378:metabolism; D006801:Humans; D006961:Hyperparathyroidism / Q000209:etiology / Q000503:physiopathology; D007408:Intestinal Absorption; D010024:Osteoporosis / Q000209:etiology / Q000503:physiopathology; D010281:Parathyroid Hormone / Q000097:blood*; D010758:Phosphorus / Q000378:metabolism; D018167:Receptors, Calcitriol / Q000378:metabolism; D052878:Urolithiasis / Q000097:blood / Q000150:complications*; D014807:Vitamin D / Q000031:analogs & derivatives / Q000097:blood / Q000627:therapeutic use; D014808:Vitamin D Deficiency / Q000097:blood / Q000150:complications* / Q000188:drug therapy
chemical_list: D010281:Parathyroid Hormone; D018167:Receptors, Calcitriol; D014807:Vitamin D; D010758:Phosphorus; C104450:25-hydroxyvitamin D; D002118:Calcium
keywords: Hormona paratiroidea; Litiasis urinaria; Metabolismo fosfocálcico; Parathyroid hormone; Phosphocalcic metabolism; Urinary lithiasis; Vitamin D; Vitamina D