title: [Primary immune thrombocytopenia in adults in Mexico: national characteristics and the relation to international literature].
abstract: In order to identify the clinical approach of a sample of Mexican hematologists for primary immune thrombocytopenia (ITP) in adults in Mexico, we applied an electronic survey via the internet to identify common practices for the diagnosis and treatment of ITP and draw a comparison between the information from these hematologists with international guidelines or the international literature. The results were analyzed using measures of central tendency. The sample was 21 medical hematologists, predominantly from Mexico City (average age: 51.4 years). A total of 66.7% of the surveyed physicians use international guidelines to make therapeutic decisions, and 43% defined ITP including the numerical concept (< 100 x 10(9)/l). We found some differences between requested clinical exams and tests indicated by the guidelines. In first-line treatment (except emergency), 91% of the participants start with prednisone and 24% use dexamethasone. Danazol is used in persistent ITP by most (41%) of the specialists. In second-line treatment, 67% would indicate splenectomy. Some differences were found between clinical practice of the hematologists in Mexico versus guidelines recommendations.
authors.affiliation: Servicio de Hematología, Hospital de Especialidades «Dr. Bernardo Sepúlveda», Centro Médico Nacional (CMN) Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), México, D.F.
authors.forename: Luis Antonio
authors.initials: LA
authors.lastname: Meillón-García
authors.affiliation: Clínica de Hemostasia y Trombosis, Hospital de Especialidades, CMN La Raza, IMSS, México, D.F.
authors.forename: Jaime
authors.initials: J
authors.lastname: García-Chávez
authors.affiliation: Servicio de Hematología, Hospital Universitario, Universidad Autónoma de Nuevo León, Monterrey.
authors.forename: David
authors.initials: D
authors.lastname: Gómez-Almaguer
authors.affiliation: Servicio de Hematología, Hospital de Especialidades «Dr. Bernardo Sepúlveda», Centro Médico Nacional (CMN) Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), México, D.F.
authors.forename: Guillermo R
authors.initials: GR
authors.lastname: Gutiérrez-Espíndola
authors.affiliation: Banco Central de Sangre, CMN Siglo XXI, IMSS, Clínica de Hemostasia y Trombosis, Hospital General de México, Secretaría de Salud, México, D.F.
authors.forename: Carlos
authors.initials: C
authors.lastname: Martínez-Murillo
mesh_terms: D000328:Adult; D000368:Aged; D006405:Hematology; D006801:Humans; D038622:Internationality; D008800:Mexico; D008875:Middle Aged; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000175:diagnosis* / Q000628:therapy*; D012196:Review Literature as Topic