title: Genome-wide association studies: the good, the bad and the ugly.
authors.affiliation: Genetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, Exeter, UK T.M.Frayling@exeter.ac.uk.
authors.forename: T M
authors.initials: TM
authors.lastname: Frayling
mesh_terms: D014644:Genetic Variation; D055106:Genome-Wide Association Study; D006801:Humans; D008659:Metabolic Diseases / Q000235:genetics; D009765:Obesity / Q000235:genetics; D010641:Phenotype
keywords: Genetic variants; genome-wide association studies; single nucleotide polymorphisms
references.citation: PLoS Genet. 2007 Jul;3(7):e115
references.pmid: 17658951
references.citation: Diabetes. 2008 Nov;57(11):3129-35
references.pmid: 18591388
references.citation: Nat Genet. 2014 Feb;46(2):136-143
references.pmid: 24413736
references.citation: Nat Genet. 2011 Dec 11;44(1):67-72
references.pmid: 22158537
references.citation: N Engl J Med. 2007 Aug 2;357(5):443-53
references.pmid: 17634449
references.citation: Nat Genet. 2013 Nov;45(11):1274-1283
references.pmid: 24097068
references.citation: PLoS Genet. 2013;9(1):e1003166
references.pmid: 23300482
references.citation: Breast Cancer Res. 2011;13(6):R110
references.pmid: 22053997
references.citation: Hum Mol Genet. 2014 Jan 1;23(1):239-46
references.pmid: 23945395
references.citation: Ann Intern Med. 2013 Dec 3;159(11):758-69
references.pmid: 24297192
references.citation: Nat Genet. 2007 Jun;39(6):724-6
references.pmid: 17496892
references.citation: Nature. 2014 Mar 20;507(7492):371-5
references.pmid: 24646999
references.citation: Nat Genet. 2011 Aug 28;43(10):984-9
references.pmid: 21874001
references.citation: Nat Genet. 2012 Sep;44(9):981-90
references.pmid: 22885922
references.citation: Science. 2007 May 11;316(5826):889-94
references.pmid: 17434869
references.citation: Hum Mol Genet. 2011 Oct 15;20(20):4069-75
references.pmid: 21757498
references.citation: Nat Genet. 2010 Nov;42(11):937-48
references.pmid: 20935630
references.citation: PLoS Genet. 2014 Feb 13;10(2):e1004137
references.pmid: 24550740
references.citation: Nat Genet. 2007 Oct;39(10):1245-50
references.pmid: 17767157
references.citation: Science. 2007 Nov 30;318(5855):1469-72
references.pmid: 17991826
references.citation: Am J Hum Genet. 2014 Apr 3;94(4):522-32
references.pmid: 24656864
references.citation: Hum Mol Genet. 2011 Jan 1;20(1):186-92
references.pmid: 20952801
references.citation: Nat Genet. 2006 Mar;38(3):320-3
references.pmid: 16415884
references.citation: Nature. 2010 Aug 5;466(7307):707-13
references.pmid: 20686565
references.citation: Nat Genet. 2010 Dec;42(12):1086-92
references.pmid: 21076408
references.citation: J Natl Cancer Inst. 2013 Jun 5;105(11):812-22
references.pmid: 23628597
references.citation: Nature. 2014 Feb 6;506(7486):97-101
references.pmid: 24390345
references.citation: Nature. 2010 Oct 14;467(7317):832-8
references.pmid: 20881960
references.citation: Diabetes. 2010 Jan;59(1):266-71
references.pmid: 19794065
references.citation: Nat Genet. 2011 Jun 26;43(8):753-60
references.pmid: 21706003
references.citation: Nat Genet. 2009 Oct;41(10):1110-5
references.pmid: 19734900