title: A change of heart: reopening of a foramen ovale.
abstract: Platypnea-orthodeoxia is a rare syndrome characterized by dyspnea and hypoxemia that is exacerbated by assuming an upright position. The most common cause is intracardiac shunting through an atrial septal defect or patent foramen ovale (PFO). We present a 63-year-old man with dyspnea after right pneumonectomy for lung cancer, who was found to have a large PFO with right-to-left shunt in the presence of normal right-sided pressures. Percutaneous closure of the PFO led to resolution of symptoms.
authors.affiliation: Department of Internal Medicine-Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA. Electronic address: vidyabpai@gmail.com.
authors.forename: Vidya B
authors.initials: VB
authors.lastname: Pai
authors.affiliation: Division of Cardiovascular Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
authors.forename: Srikanth
authors.initials: S
authors.lastname: Vallurupalli
authors.affiliation: Division of Cardiovascular Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
authors.forename: Srikanth R
authors.initials: SR
authors.lastname: Kasula
authors.affiliation: Division of Cardiovascular Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
authors.forename: Abdul
authors.initials: A
authors.lastname: Hakeem
authors.affiliation: Division of Cardiovascular Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
authors.forename: Sabha
authors.initials: S
authors.lastname: Bhatti
mesh_terms: D004417:Dyspnea / Q000209:etiology; D054092:Foramen Ovale, Patent / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D000860:Hypoxia / Q000209:etiology; D008175:Lung Neoplasms / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000378:metabolism; D062645:Percutaneous Coronary Intervention; D011013:Pneumonectomy; D011183:Postoperative Complications / Q000601:surgery; D011187:Posture; D019919:Prosthesis Implantation / Q000379:methods; D055989:Septal Occluder Device; D013577:Syndrome
chemical_list: D010100:Oxygen