title: What is the need for comparative effectiveness studies in IBD?
abstract: Unlike traditional clinical trial research, Comparative Effectiveness Research seeks to determine what is 'best' for a typical patient when deciding between effective options used in daily practice - a therapy, diagnostic test, or course of action. There is a clear need for Comparative Effectiveness Research in Inflammatory Bowel Disease, a point emphasized by the Institute of Medicine and supported by governmental agencies and escalating funding. This review highlights the rationale and support for Comparative Effectiveness Research, provides examples of Comparative Effectiveness Research in Inflammatory Bowel Disease, and outlines current and future focus for Comparative Effectiveness Research in Inflammatory Bowel Disease.
authors.affiliation: Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, 100 N. Greene Street, Lower Level, Baltimore, MD 21201, USA.
authors.forename: Mark H
authors.initials: MH
authors.lastname: Flasar
authors.forename: Raymond K
authors.initials: RK
authors.lastname: Cross
mesh_terms: D057186:Comparative Effectiveness Research; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*
keywords: Crohn’s disease; comparative effectiveness research; inflammatory bowel disease; ulcerative colitis