title: [Prognostication of course and treatment of peripancreatic infiltrate in patients, suffering an acute necrotic pancreatitis].
abstract: Results of treatment of 229 patients, suffering an acute necrotic pancreatitis, complicated by peripancreatic infiltrate, were analyzed. To all the patients antibiotic prophylaxis and antibiotic therapy were conducted. In 63 (27.5%) patients the methods of extracorporal hemocorrection were applied, and in 108 (47.1%)--the "four--catheters" rule (catheter for epidural anesthesia, installment of the feeding intestinal probe further than the Treitz ligament level, the central vein catheterization, the programmed laparocentesis). In 31 (13.5%) patients there were determined the activity of mononuclear phagocytes and production of ROS (the oxygen active forms) by them in peripheral blood with objective for the purulent-septic complications prognostication. In 14 (6.1%) patients purulent--septic complications have occurred, postoperative lethality was 21.4%, general lethality--3.4%.
authors.forename: Ia M
authors.initials: IaM
authors.lastname: Susak
authors.forename: O A
authors.initials: OA
authors.lastname: Tkachenko
authors.forename: I R
authors.initials: IR
authors.lastname: Malysh
authors.forename: O O
authors.initials: OO
authors.lastname: Dirda
authors.forename: O H
authors.initials: OH
authors.lastname: Fedorchuk
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001202:Ascitic Fluid / Q000187:drug effects; D002408:Catheters, Indwelling; D005260:Female; D006464:Hemoperfusion; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D008297:Male; D008875:Middle Aged; D019283:Pancreatitis, Acute Necrotizing / Q000150:complications / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy*; D011379:Prognosis; D017382:Reactive Oxygen Species / Q000378:metabolism; D018805:Sepsis / Q000175:diagnosis* / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D017382:Reactive Oxygen Species