title: History and update of HTLV infection in China.
abstract: Human T-lymphotropic virus (HTLV) infection is a high risk factor for lymphoproliferative, inflammatory, and infectious disorders. The epidemiology of HTLV-I, II in industrialized countries has been intensively investigated, and mandatory screening of blood supplies for HTLV-I/II was implemented in mid-1980s in most developed and several developing countries, yet no expanding investigation has been executed in China so far and also been considered as a non-endemic region. However, Gessain et al. reported that the current number of HTLV carriers in the highly populated China is very probably much higher. Therefore, gaining insight into the epidemiology of HTLV infections is essential for avoiding HTLV-induced risk. To introduce the history and renew the HTLV infection in China, we reviewed literatures and conducted an investigation among blood donors in 9 provinces in China. Concluded from the historical and renewed data, the HTLV screen in China can be divided into three stages.
authors.affiliation: National Institutes for Food and Drug Control, Beijing, China. Electronic address: dujialiang@nifdc.org.cn.
authors.forename: Jialiang
authors.initials: J
authors.lastname: Du
authors.affiliation: Xiamen Blood Center, Xiamen, Fujian Province, China. Electronic address: ccr1969@163.com.
authors.forename: Changrong
authors.initials: C
authors.lastname: Chen
authors.affiliation: National Institutes for Food and Drug Control, Beijing, China.
authors.forename: Jiamei
authors.initials: J
authors.lastname: Gao
authors.affiliation: Xiamen Blood Center, Xiamen, Fujian Province, China.
authors.forename: Jinzhen
authors.initials: J
authors.lastname: Xie
authors.affiliation: Guangzhou Blood Center, Guangzhou, Guangdong Province, China.
authors.forename: Xia
authors.initials: X
authors.lastname: Rong
authors.affiliation: Shenzhen Blood Center, Shenzhen, Guangdong Province, China.
authors.forename: Xiaoxun
authors.initials: X
authors.lastname: Xu
authors.affiliation: Zhejiang Blood Center, Hangzhou, Zhejiang Province, China.
authors.forename: Yongjun
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Liaoning Blood Center, Shenyang, Liaoning Province, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Wang
authors.affiliation: Henan Red Cross Blood Center, Zhengzhou, Henan Province, China.
authors.forename: Jianbin
authors.initials: J
authors.lastname: Li
authors.affiliation: Shandong Provincial Hospital, Jinan, Shandong Province, China.
authors.forename: Zhiming
authors.initials: Z
authors.lastname: Lu
authors.affiliation: Urumqi Blood Center, Urumqi, Xinjiang Province, China.
authors.forename: Weipeng
authors.initials: W
authors.lastname: Guo
authors.affiliation: Jiangxi Blood Center, Nanchang, Jiangxi Province, China.
authors.forename: Guoliang
authors.initials: G
authors.lastname: Li
authors.affiliation: Shanghai Blood Center, Shanghai, China.
authors.forename: Zhongying
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Ningde Blood Center, Ningde, Fujian Province, China.
authors.forename: Dongfeng
authors.initials: D
authors.lastname: Xu
authors.affiliation: Putian Blood Center, Putian, Fujian Province, China.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Weng
authors.affiliation: Zhangzhou Blood Center, Zhangzhou, Fujian Province, China.
authors.forename: Zhijian
authors.initials: Z
authors.lastname: Zhao
authors.affiliation: Longyan Blood Center, Longyan, Fujian Province, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Weng
authors.affiliation: Zhoushan Blood Center, Zhoushan, Zhejiang Province, China.
authors.forename: Haoru
authors.initials: H
authors.lastname: Li
authors.affiliation: Ningbo Blood Center, Ningbo, Zhejiang Province, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Du
authors.affiliation: Jiaxing Blood Center, Jiaxing, Zhejiang Province, China.
authors.forename: Song
authors.initials: S
authors.lastname: Li
authors.affiliation: Taizhou Blood Center, Taizhou, Zhejiang Province, China.
authors.forename: Chaohui
authors.initials: C
authors.lastname: Zhen
authors.affiliation: Wenzhou Blood Center, Wenzhou, Zhejiang Province, China.
authors.forename: Baolin
authors.initials: B
authors.lastname: Liu
authors.affiliation: National Institutes for Food and Drug Control, Beijing, China. Electronic address: guotai@nifdc.org.cn.
authors.forename: Tai
authors.initials: T
authors.lastname: Guo
mesh_terms: D002681:China / Q000453:epidemiology; D015490:HTLV-I Infections / Q000453:epidemiology* / Q000266:history* / Q000821:virology; D049673:History, 20th Century; D049674:History, 21st Century; D015368:Human T-lymphotropic virus 1 / Q000235:genetics / Q000502:physiology*; D015367:Human T-lymphotropic virus 2 / Q000235:genetics / Q000502:physiology*; D006801:Humans
keywords: China; HTLV infection; History; Update