title: Comparison of risk factors in HIV-infected men who have sex with men, coinfected or not with hepatitis C virus (ANRS VESPA2 French cross-sectional national survey).
abstract: OBJECTIVE
  HIV-infected men who have sex with men (HIV-MSM) are at high risk of hepatitis C virus (HCV) infection. This study aimed to compare risk factors between HIV-MSM coinfected with HCV and those who are not, in a national representative survey conducted in France.
  
  
  METHODS
  The ANRS VESPA2 survey (April 2011-January 2012) collected sociodemographic and behavioural data (through face-to-face administered questionnaires) as well as medical data (physician questionnaire) among 3022 HIV-infected adults recruited in 73 French HIV hospital departments. We identified behavioural correlates of HCV coinfection among sexually active HIV-MSM who participated in VESPA2 (logistic regression models).
  
  
  RESULTS
  Ninety-three of the 1037 HIV-MSM of the study population (8.9%) were coinfected with HCV. The following risk factors were independently associated with HCV coinfection, after adjustment for age and time since HIV diagnosis: current or past injecting drug use, having had at least 20 male sexual partners during the previous 12 months, reporting inconsistent condom use during anal sex with casual partners, and attending sex parties. Individuals reporting at least three sexual risk factors were at the highest risk of being coinfected with HCV (OR (95% CI): 22.86 (9.74; 53.62), p<0.0001).
  
  
  CONCLUSIONS
  HIV-MSM reporting several sexual risk factors should be sensitised to risk-reduction behaviours to avoid HCV transmission to sexual partners, and infection or reinfection with HCV.
authors.affiliation: INSERM, UMR912 (SESSTIM), 13006, Marseille, France Aix Marseille Université, UMR_S912, IRD, 13006, Marseille, France ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, 13006, Marseille, France.
authors.forename: Fabienne
authors.identifier: http://orcid.org/0000-0001-8853-3829
authors.initials: F
authors.lastname: Marcellin
authors.affiliation: INSERM, UMR912 (SESSTIM), 13006, Marseille, France Aix Marseille Université, UMR_S912, IRD, 13006, Marseille, France ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, 13006, Marseille, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Lorente
authors.affiliation: INSERM, UMR912 (SESSTIM), 13006, Marseille, France Aix Marseille Université, UMR_S912, IRD, 13006, Marseille, France ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, 13006, Marseille, France.
authors.forename: Baptiste
authors.initials: B
authors.lastname: Demoulin
authors.affiliation: INSERM, UMR912 (SESSTIM), 13006, Marseille, France Aix Marseille Université, UMR_S912, IRD, 13006, Marseille, France ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, 13006, Marseille, France.
authors.forename: Maria Patrizia
authors.initials: MP
authors.lastname: Carrieri
authors.affiliation: INSERM, UMR912 (SESSTIM), 13006, Marseille, France Aix Marseille Université, UMR_S912, IRD, 13006, Marseille, France ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, 13006, Marseille, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Suzan-Monti
authors.affiliation: INSERM, UMR912 (SESSTIM), 13006, Marseille, France Aix Marseille Université, UMR_S912, IRD, 13006, Marseille, France ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, 13006, Marseille, France.
authors.forename: Perrine
authors.initials: P
authors.lastname: Roux
authors.affiliation: Centre de recherche en épidémiologie et santé des populations, Inserm U1018, Villejuif, France Université de Versailles Saint-Quentin-en-Yvelines, UMRS 1018, Villejuif, France.
authors.forename: France
authors.initials: F
authors.lastname: Lert
authors.affiliation: INSERM, UMR912 (SESSTIM), 13006, Marseille, France Aix Marseille Université, UMR_S912, IRD, 13006, Marseille, France ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, 13006, Marseille, France.
authors.forename: Luis
authors.initials: L
authors.lastname: Sagaon-Teyssier
authors.affiliation: INSERM, UMR_S1136, Pierre Louis Institute of Epidemiology and Public Health, Team Research in social epidemiology, F-75013, Paris, France Sorbonne Universités, UPMC Univ Paris 06, UMR_S1136, Pierre Louis Institute of Epidemiology and Public Health, Team Research in social epidemiology, F-75013, Paris, France.
authors.forename: Rosemary
authors.initials: R
authors.lastname: Dray-Spira
authors.affiliation: INSERM, UMR912 (SESSTIM), 13006, Marseille, France Aix Marseille Université, UMR_S912, IRD, 13006, Marseille, France ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, 13006, Marseille, France.
authors.forename: Bruno
authors.initials: B
authors.lastname: Spire
mesh_terms: D000328:Adult; D001519:Behavior; D003430:Cross-Sectional Studies; D005602:France / Q000453:epidemiology; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology*; D019698:Hepatitis C, Chronic / Q000453:epidemiology* / Q000635:transmission*; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D012307:Risk Factors
keywords: DRUG ADDICTION; GAY MEN; HEPATITIS C; HIV; SEXUAL BEHAVIOUR