title: Atom-economical access to highly substituted indenes and furan-2-ones via tandem reaction of diazo compounds and propargyl alcohols.
abstract: A facile synthesis of highly substituted as well as conjugated indene/furanone systems via a BF3·OEt2 catalyzed tandem reaction of α-diazo-esters/-amides and propargyl alcohols has been demonstrated under mild conditions. This method offers great potential for the synthesis of biologically active indene and furanone derivatives and their related polycyclic compounds.
authors.affiliation: School of Chemistry, Bharathidasan University , Tiruchirappalli, 620024, India.
authors.forename: Sengodagounder
authors.initials: S
authors.lastname: Muthusamy
authors.forename: Manickasamy
authors.initials: M
authors.lastname: Sivaguru
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001391:Azo Compounds / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D007192:Indenes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011083:Polycyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D020005:Propanols / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001391:Azo Compounds; D005663:Furans; D007192:Indenes; D011083:Polycyclic Compounds; D020005:Propanols; C028255:propargyl alcohol