title: Self-powered glucose-responsive micropumps.
abstract: A self-powered polymeric micropump based on boronate chemistry is described. The pump is triggered by the presence of glucose in ambient conditions and induces convective fluid flows, with pumping velocity proportional to the glucose concentration. The pumping is due to buoyancy convection that originates from reaction-associated heat flux, as verified from experiments and finite difference modeling. As predicted, the fluid flow increases with increasing height of the chamber. In addition, pumping velocity is enhanced on replacing glucose with mannitol because of the enhanced exothermicity associated with the reaction of the latter.
authors.affiliation: Department of Chemistry and ‡Department of Engineering Science and Mechanics, The Pennsylvania State University , University Park, Pennsylvania 16802, United States.
authors.forename: Hua
authors.initials: H
authors.lastname: Zhang
authors.forename: Wentao
authors.initials: W
authors.lastname: Duan
authors.forename: Mengqian
authors.initials: M
authors.lastname: Lu
authors.forename: Xi
authors.initials: X
authors.lastname: Zhao
authors.forename: Sergey
authors.initials: S
authors.lastname: Shklyaev
authors.forename: Lei
authors.initials: L
authors.lastname: Liu
authors.forename: Tony Jun
authors.initials: TJ
authors.lastname: Huang
authors.forename: Ayusman
authors.initials: A
authors.lastname: Sen
mesh_terms: D001897:Boronic Acids / Q000737:chemistry; D016503:Drug Delivery Systems / Q000379:methods*; D005947:Glucose / Q000737:chemistry*; D057446:Hydrodynamics; D055616:Microtechnology / Q000379:methods*; D013499:Surface Properties; D013696:Temperature
chemical_list: D001897:Boronic Acids; D005947:Glucose