title: Acupuncture mechanism and redox equilibrium.
abstract: Oxidative stress participates in the pathological process of various diseases. Acupuncture is a component of the health care system in China that can be traced back for at least 3000 years. Recently, increased evidences indicate that acupuncture stimulation could reduce oxidative damage in organisms under pathological state, but the exact mechanism remains unclear. This review focuses on the emerging links between acupuncture and redox modulation in various disorders, such as vascular dementia, Parkinson's disease, and hypertension, ranging from redox system, antioxidant system, anti-inflammatory system, and nervous system to signaling pathway. Although the molecular and cellular pathways studies of acupuncture effect on oxidative stress are preliminary, they represent an important step forward in the research of acupuncture antioxidative effect.
authors.affiliation: Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, 23 Meishuguanhou Street, Dongcheng District, Beijing 100010, China ; Acupuncture and Moxibustion College, Tianjin University of Traditional Chinese Medicine, No. 312, Anshan West Road, Nankai District, Tianjin 300193, China.
authors.forename: Xiang-Hong
authors.initials: XH
authors.lastname: Zeng
authors.affiliation: Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, 23 Meishuguanhou Street, Dongcheng District, Beijing 100010, China.
authors.forename: Qian-Qian
authors.initials: QQ
authors.lastname: Li
authors.affiliation: Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, 23 Meishuguanhou Street, Dongcheng District, Beijing 100010, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Xu
authors.affiliation: Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, 23 Meishuguanhou Street, Dongcheng District, Beijing 100010, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Li
authors.affiliation: Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, 23 Meishuguanhou Street, Dongcheng District, Beijing 100010, China.
authors.forename: Cun-Zhi
authors.initials: CZ
authors.lastname: Liu
references.citation: Life Sci. 2005 Jun 10;77(4):386-99
references.pmid: 15894008
references.citation: Anesth Analg. 2007 Mar;104(3):646-54
references.pmid: 17312224
references.citation: Zhen Ci Yan Jiu. 2009 Feb;34(1):48-51
references.pmid: 19526808
references.citation: Acta Cir Bras. 2013 Aug;28(8):582-8
references.pmid: 23896837
references.citation: Neurochem Res. 2004 Dec;29(12):2239-43
references.pmid: 15672545
references.citation: Acta Cir Bras. 2011;26 Suppl 1:60-5
references.pmid: 21971660
references.citation: J Neural Transm. 1988;74(3):199-205
references.pmid: 3210014
references.citation: J Biomed Sci. 2006 Jan;13(1):127-41
references.pmid: 16283433
references.citation: Hypertens Res. 2011 Jan;34(1):5-14
references.pmid: 20981034
references.citation: Neurochem Int. 2014 Jan;65:23-9
references.pmid: 24361538
references.citation: World J Gastroenterol. 2009 Feb 28;15(8):973-7
references.pmid: 19248197
references.citation: Aesthetic Plast Surg. 2012 Oct;36(5):1230-5
references.pmid: 22678136
references.citation: Ann Neurol. 2002 Aug;52(2):175-9
references.pmid: 12210787
references.citation: J Alzheimers Dis. 2010;22(2):593-607
references.pmid: 20847409
references.citation: Exp Neurol. 2004 Sep;189(1):189-96
references.pmid: 15296849
references.citation: Ann N Y Acad Sci. 1998 Nov 20;854:448-62
references.pmid: 9928452
references.citation: Am J Physiol Cell Physiol. 2008 Oct;295(4):C849-68
references.pmid: 18684987
references.citation: Oxid Med Cell Longev. 2013;2013:316523
references.pmid: 23983897
references.citation: Neurol Res. 2010 Feb;32 Suppl 1:5-9
references.pmid: 20034437
references.citation: CMAJ. 2010 Nov 9;182(16):1711-2
references.pmid: 20876262
references.citation: Int J Cardiol. 2013 Nov 20;169(5):317-26
references.pmid: 24060112
references.citation: J Tradit Chin Med. 2013 Jun;33(3):399-402
references.pmid: 24024340
references.citation: J Alzheimers Dis. 2004 Aug;6(4):385-9; discussion 443-9
references.pmid: 15345808
references.citation: Ann Neurol. 1992;32 Suppl:S51-61
references.pmid: 1510381
references.citation: J Tradit Chin Med. 2012 Jun;32(2):199-202
references.pmid: 22876443
references.citation: J Neurochem. 2012 Jan;120(2):292-301
references.pmid: 22050439
references.citation: ACS Chem Biol. 2013 May 17;8(5):856-65
references.pmid: 23506614
references.citation: PLoS One. 2014 Mar 13;9(3):e91426
references.pmid: 24626220
references.citation: Neurosci Lett. 2006 May 15;399(1-2):11-6
references.pmid: 16516385
references.citation: J Mol Neurosci. 2004;24(3):401-16
references.pmid: 15655262
references.citation: J Endocrinol Invest. 2011 Nov;34(10):e355-61
references.pmid: 21750401
references.citation: Neurosci Lett. 2005 Aug 12-19;384(1-2):133-8
references.pmid: 15893426
references.citation: Exp Neurol. 2012 Aug;236(2):268-82
references.pmid: 22634758
references.citation: Antioxid Redox Signal. 2008 Oct;10(10):1713-65
references.pmid: 18707220
references.citation: Neuroepidemiology. 2014;42(1):50-8
references.pmid: 24356063
references.citation: CNS Neurosci Ther. 2011 Oct;17(5):398-410
references.pmid: 21091639
references.citation: Biochem Biophys Res Commun. 2000 Feb 24;268(3):916-20
references.pmid: 10679305
references.citation: Antioxid Redox Signal. 2014 Jan 1;20(1):146-63
references.pmid: 23418728
references.citation: Kidney Blood Press Res. 2012;35(6):634-43
references.pmid: 22964493
references.citation: Neurosci Lett. 2006 Jan 23;393(1):45-50
references.pmid: 16236447
references.citation: J Biol Chem. 2014 May 30;289(22):15611-20
references.pmid: 24722990
references.citation: Antioxid Redox Signal. 2003 Oct;5(5):597-607
references.pmid: 14580316
references.citation: Oxid Med Cell Longev. 2012;2012:624925
references.pmid: 22829959
references.citation: PLoS One. 2011;6(5):e19790
references.pmid: 21625423
references.citation: J Acupunct Meridian Stud. 2012 Dec;5(6):295-300
references.pmid: 23265080
references.citation: Exp Neurol. 2013 Jan;239:163-9
references.pmid: 23059458
references.citation: Brain Res. 2012 Jan 13;1432:36-45
references.pmid: 22129788
references.citation: Neurol Sci. 2013 Mar;34(3):305-12
references.pmid: 22391677
references.citation: Biotechnol Lett. 2012 Jul;34(7):1175-82
references.pmid: 22421970
references.citation: Neurobiol Dis. 2010 Sep;39(3):272-82
references.pmid: 20382225
references.citation: Zhongguo Zhen Jiu. 2010 Jan;30(1):18-21
references.pmid: 20353108
references.citation: Free Radic Biol Med. 2001 Dec 1;31(11):1287-312
references.pmid: 11728801
references.citation: Brain Res. 2010 Jun 8;1336:58-65
references.pmid: 20399757
references.citation: Oxid Med Cell Longev. 2012;2012:240146
references.pmid: 22701755
references.citation: Hypertens Res. 2011 Apr;34(4):431-40
references.pmid: 21228777
references.citation: Drug Metab Rev. 1998 May;30(2):225-43
references.pmid: 9606602
references.citation: Life Sci. 2004 Jul 30;75(11):1323-32
references.pmid: 15234190
references.citation: Free Radic Biol Med. 2006 Jun 1;40(11):2028-39
references.pmid: 16716903
references.citation: CNS Neurol Disord Drug Targets. 2007 Dec;6(6):411-23
references.pmid: 18220780
references.citation: Annu Rev Pharmacol Toxicol. 2007;47:143-83
references.pmid: 17029566
references.citation: Trends Mol Med. 2008 Nov;14(11):495-502
references.pmid: 18929509
references.citation: Physiol Behav. 2009 Jan 8;96(1):155-61
references.pmid: 18938189
references.citation: Gene. 2013 Feb 25;515(2):329-38
references.pmid: 23235115
references.citation: J Physiol Sci. 2010 Jan;60(1):27-34
references.pmid: 19760485
references.citation: Int J Alzheimers Dis. 2012;2012:630182
references.pmid: 22482074
references.citation: Ann N Y Acad Sci. 2004 Mar;1012:14-26
references.pmid: 15105252
references.citation: Mol Cells. 2008 Apr 30;25(2):178-83
references.pmid: 18413997
references.citation: Parkinsons Dis. 2011 Mar 15;2011:716871
references.pmid: 21461368
references.citation: Neurosci Lett. 2004 Jan 9;354(2):158-62
references.pmid: 14698462
references.citation: PLoS One. 2011;6(11):e27566
references.pmid: 22132113
references.citation: Can J Neurol Sci. 2012 Jan;39(1):65-8
references.pmid: 22384487
references.citation: Int J Clin Pract. 2009 Jun;63(6):874-9
references.pmid: 19490197
references.citation: Evid Based Complement Alternat Med. 2014;2014:279478
references.pmid: 24723957
references.citation: Brain Res Bull. 2013 Aug;97:53-62
references.pmid: 23751198
references.citation: Brain Res. 2007 Feb 2;1131(1):211-9
references.pmid: 17173870
references.citation: Free Radic Biol Med. 2011 Dec 15;51(12):2163
references.pmid: 22044659
references.citation: PLoS One. 2012;7(9):e44216
references.pmid: 22984478
references.citation: Zhen Ci Yan Jiu. 2009 Jun;34(3):152-8
references.pmid: 19761106
references.citation: Int Rev Neurobiol. 2013;111:181-95
references.pmid: 24215923
references.citation: Nat Rev Genet. 2006 Aug;7(8):606-19
references.pmid: 16847462
references.citation: J Biomed Sci. 2013 Sep 18;20:69
references.pmid: 24047403