title: Copper-catalyzed decarboxylative sulfonylation of α,β-unsaturated carboxylic acids.
abstract: Copper-catalyzed, ligand-promoted decarboxylative coupling of readily available α,β-unsaturated acids with sodium aryl sulfinates is presented. This method provides a new avenue for the synthesis of vinyl sulfones via a decarboxylative radical coupling strategy by employing a catalytic amount of Cu(ClO4)2·6H2O, TBHP in decane as an oxidant, and 1,10-phenanthroline as a ligand. The salient feature of this method is that it furnishes exclusively the (E)-isomer.
authors.affiliation: Department of Organic Chemistry, Indian Institute of Science , Bangalore 560 012, Karnataka, India.
authors.forename: Balaji V
authors.initials: BV
authors.lastname: Rokade
authors.forename: Kandikere Ramaiah
authors.initials: KR
authors.lastname: Prabhu