title: Human papilloma virions in the laboratory.
abstract: Carcinogenic human papillomaviruses (HPV) can cause cervical, vaginal, vulvar, penile, anal, and oropharyngeal cancers. Non-carcinogenic HPVs can cause anogenital warts and recurrent respiratory papillomatosis. Currently, few research laboratories propagate, isolate or generate papilloma virions. However, there have been questions about potential exposure and risk in this setting. In this brief note, we discuss the use of wild type and laboratory-generated virions in research laboratories, potential routes of laboratory exposure, and considerations for HPV vaccination of laboratory personnel.
authors.affiliation: Division of STD Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Eileen F
authors.initials: EF
authors.lastname: Dunne
authors.affiliation: Division of STD Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Lauri E
authors.initials: LE
authors.lastname: Markowitz
authors.affiliation: Division of STD Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA; Epidemic Intelligence Service Fellow (EIS), Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: La'shan D
authors.initials: LD
authors.lastname: Taylor
authors.affiliation: Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Elizabeth R
authors.initials: ER
authors.lastname: Unger
authors.affiliation: Departments of Pathology and Obstetrics and Gynecology, University of New Mexico Health Sciences Center, Albuquerque, NM, USA. Electronic address: cwheeler@salud.unm.edu.
authors.forename: Cosette M
authors.initials: CM
authors.lastname: Wheeler
mesh_terms: D006801:Humans; D007753:Laboratories; D009784:Occupational Diseases / Q000517:prevention & control* / Q000821:virology; D016273:Occupational Exposure; D027383:Papillomaviridae / Q000254:growth & development* / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000517:prevention & control* / Q000821:virology; D053918:Papillomavirus Vaccines / Q000008:administration & dosage*
chemical_list: D053918:Papillomavirus Vaccines
keywords: HPV; HPV vaccines; Human papillomavirus; Laboratory safety
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