title: Stenting of the right ventricular outflow tract in 2 dogs for palliation of dysplastic pulmonary valve stenosis and right-to-left intracardiac shunting defects.
abstract: Two dogs with severe dysplastic pulmonary valve stenosis and right-to-left shunting defects (patent foramen ovale, perimembranous ventricular septal defect) underwent palliative stenting of the right ventricular outflow tract and pulmonary valve annulus using balloon expandable stents. One dog received 2 over-lapping bare metal stents placed 7 months apart; the other received a single covered stent. Both procedures were considered technically successful with a reduction in the transpulmonary valve pressure gradient from 202 to 90 mmHg in 1 dog and from 168 to 95 mmHg in the other. Clinical signs of exercise intolerance and syncope were temporarily resolved in both dogs. However, progressive right ventricular concentric hypertrophy, recurrent stenosis, and erythrocytosis were observed over the subsequent 6 months leading to poor long-term outcomes. Stenting of the right ventricular outflow tract is feasible in dogs with severe dysplastic pulmonary valve stenosis, though further study and optimization of the procedure is required.
authors.affiliation: Department of Clinical Sciences, The Ohio State University College of Veterinary Medicine, 601 Vernon L Tharp St., Columbus, OH 43210, USA. Electronic address: Brian.Scansen@cvm.osu.edu.
authors.forename: Brian A
authors.initials: BA
authors.lastname: Scansen
authors.affiliation: Department of Clinical Sciences, The Ohio State University College of Veterinary Medicine, 601 Vernon L Tharp St., Columbus, OH 43210, USA.
authors.forename: Agnieszka M
authors.initials: AM
authors.lastname: Kent
authors.affiliation: The Heart Center, Nationwide Children's Hospital, 700 Children's Dr., Columbus, OH 43205, USA.
authors.forename: Sharon L
authors.initials: SL
authors.lastname: Cheatham
authors.affiliation: The Heart Center, Nationwide Children's Hospital, 700 Children's Dr., Columbus, OH 43205, USA.
authors.forename: John P
authors.initials: JP
authors.lastname: Cheatham
authors.affiliation: The Heart Center, Nationwide Children's Hospital, 700 Children's Dr., Columbus, OH 43205, USA.
authors.forename: John D
authors.initials: JD
authors.lastname: Cheatham
mesh_terms: D000818:Animals; D002404:Catheterization / Q000662:veterinary; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000628:therapy*; D004285:Dogs; D018618:Echocardiography, Doppler, Color / Q000662:veterinary; D054092:Foramen Ovale, Patent / Q000150:complications / Q000662:veterinary*; D006345:Heart Septal Defects, Ventricular / Q000150:complications / Q000662:veterinary*; D006352:Heart Ventricles / Q000601:surgery; D008297:Male; D011666:Pulmonary Valve Stenosis / Q000628:therapy / Q000662:veterinary*; D012720:Severity of Illness Index; D015607:Stents / Q000662:veterinary*
keywords: Angiography; Canine; Congenital heart disease; Echocardiography