title: Phosphathiahelicenes: synthesis and uses in enantioselective gold catalysis.
abstract: Enantiomerically pure thiahelicenes displaying a terminal phosphole unit and a stereogenic phosphorus center have been prepared by oxidative photocyclization of a diaryl-olefin precursor. Starting from one of these phosphathiahelicene oxides, the corresponding trivalent phosphine-Au(I) complex is obtained with complete diastereoselectivity. It affords a new, excellent precatalyst for the enantioselective cycloisomerization of N-tethered enynes (up to 96 % ee).
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS UPR 2301, 1, av. De la Terrasse - 91198 Gif-sur-Yvette (France).
authors.forename: Paul
authors.initials: P
authors.lastname: Aillard
authors.forename: Arnaud
authors.initials: A
authors.lastname: Voituriez
authors.forename: Davide
authors.initials: D
authors.lastname: Dova
authors.forename: Silvia
authors.initials: S
authors.lastname: Cauteruccio
authors.forename: Emanuela
authors.initials: E
authors.lastname: Licandro
authors.forename: Angela
authors.initials: A
authors.lastname: Marinetti
keywords: enantioselectivity; enyne cycloisomerization; gold; phosphahelicenes; thiahelicenes