title: Maternal obesity influences the relationship between location of neonate fat mass and total fat mass.
abstract: BACKGROUND
  It is suggested that maternal obesity perpetuates offspring obesity to future generations.
  
  
  OBJECTIVE
  To determine whether location of neonate fat mass (FM: central vs. peripheral) is related to total neonate FM and whether maternal obesity influences this relationship.
  
  
  METHODS
  Neonate body composition and skin-fold thicknesses were assessed in healthy neonates (n = 371; 1-3 days old). Linear regression models examined the relationship between total FM and location of FM (central vs. peripheral). Location of FM was calculated by skin-folds: peripheral was the sum of (biceps and triceps)/2 and central was represented by the subscapular skin-fold.
  
  
  RESULTS
  A significant interaction was found for location of FM and maternal obesity. Holding all predictors constant, in offspring born to non-obese mothers, a 0.5 mm increase in central FM predicted a 15 g greater total FM, whereas a 0.5 mm increase in peripheral FM predicted a 66 g greater total FM. However, in offspring born to obese mothers, a 0.5 mm increase in central FM predicted a 56 g total FM, whereas a 0.5 mm increase in peripheral FM predicted a 14 g greater total FM.
  
  
  CONCLUSIONS
  The relationship between total FM and location of FM is influenced by maternal obesity.
authors.affiliation: Department of Dietetics and Nutrition, University of Kansas Medical Center, Kansas City, KS, USA.|New York Obesity Nutrition Research Center, Columbia University, St. Luke's-Roosevelt Hospital, New York, NY, USA.
authors.forename: H R
authors.initials: HR
authors.lastname: Hull
authors.affiliation: New York Obesity Nutrition Research Center, Columbia University, St. Luke's-Roosevelt Hospital, New York, NY, USA.
authors.forename: J
authors.initials: J
authors.lastname: Thornton
authors.affiliation: Department of Pediatrics, St. Luke's-Roosevelt Hospital, New York, NY, USA.
authors.forename: C
authors.initials: C
authors.lastname: Paley
authors.affiliation: Department of Nutritional Sciences, Hunter College, New York, NY, USA.
authors.forename: K
authors.initials: K
authors.lastname: Navder
authors.affiliation: New York Obesity Nutrition Research Center, Columbia University, St. Luke's-Roosevelt Hospital, New York, NY, USA.
authors.forename: D
authors.initials: D
authors.lastname: Gallagher
mesh_terms: D000328:Adult; D001823:Body Composition; D050218:Body Fat Distribution; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009035:Mothers; D009765:Obesity / Q000150:complications*; D012885:Skinfold Thickness
keywords: Fat pattern; maternal obesity; neonate body composition; neonate fat mass
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