title: Response to rituximab in a case of lupus associated digital ischemia.
abstract: We report the case of a 38-year-old female patient with systemic lupus erythematosus (SLE) and Jaccoud arthritis (JA) that sequentially developed digital ischemic lesions of the hands. In spite of follow-up treatment with glucocorticoids, immunosuppressant, antiaggregant, and potent vasodilatator agents, a serious progression to digital gangrene over a one-month period was observed. Surprisingly, her nonhealing digital lesions improved after two cycles of rituximab (RTX) administration.
authors.affiliation: Department of Rheumatology, Ankara University Medical Faculty, Sihhiye, 06410 Ankara, Turkey.
authors.forename: Orhan
authors.initials: O
authors.lastname: Küçükşahin
authors.affiliation: Department of Rheumatology, Ankara University Medical Faculty, Sihhiye, 06410 Ankara, Turkey.
authors.forename: Nurşen
authors.initials: N
authors.lastname: Düzgün
authors.affiliation: Department of Internal Medicine, Ankara University Medical Faculty, Sihhiye, 06410 Ankara, Turkey.
authors.forename: Alexis K
authors.initials: AK
authors.lastname: Okoh
authors.affiliation: Department of Internal Medicine, Ankara University Medical Faculty, Sihhiye, 06410 Ankara, Turkey.
authors.forename: Emre
authors.initials: E
authors.lastname: Kulahçioglu
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