title: Residential exposure to volatile organic compounds and lung function: results from a population-based cross-sectional survey.
abstract: Exposure to residential volatile organic compounds (VOCs) is ubiquitous in homes, and may influence respiratory health with important public health implications. To investigate the association between VOCs measured in residential indoor air and lung function in the Canadian population Cycle 2 of the Canadian Health Measures Survey - a population based cross-sectional survey designed to be representative of the Canadian population - was carried out between 2009 and 2011. Of the 84 VOCs measured, 47 were detectable in at least 50% of homes and ten were negatively associated with lung function: decanal, 2-furancarboxaldehyde, hexanal, nonanal, octanal, benzene, styrene, α-pinene, 2-methyl-1,2-butadiene and naphthalene. Differences were observed between males and females, as well as by age, and significant associations were most frequent in those under 17 years. These results provide evidence that some VOCs measured indoors are negatively associated with lung function in the Canadian population.
authors.affiliation: Population Studies Division, Environmental Health Science & Research Bureau, Health Canada, 50 Columbine Driveway, Ottawa, ON K1A 0K9, Canada. Electronic address: sabit.cakmak@hc-sc.gc.ca.
authors.forename: Sabit
authors.initials: S
authors.lastname: Cakmak
authors.affiliation: University of Ottawa, 501 Smyth Road, Ottawa, ON K1H 8L6, Canada; Ottawa Hospital Research Institute, Canada; Population Studies Division, Environmental Health Science & Research Bureau, Health Canada, 200 Eglantine Driveway, AL 1915B, Ottawa, ON K1A 0K9, Canada. Electronic address: rdales@ohri.ca.
authors.forename: Robert E
authors.initials: RE
authors.lastname: Dales
authors.affiliation: Population Studies Division, Environmental Health Science & Research Bureau, Health Canada, 200 Eglantine Driveway, AL 1915B, Ottawa, ON K1A 0K9, Canada. Electronic address: ling.liu@hc-sc.gc.ca.
authors.forename: Ling
authors.initials: L
authors.lastname: Liu
authors.affiliation: Population Studies Division, Environmental Health Science & Research Bureau, Health Canada, 200 Eglantine Driveway, AL 1915B, Ottawa, ON K1A 0K9, Canada. Electronic address: Lisa.Marie.Kauri@hc-sc.gc.ca.
authors.forename: Lisa Marie
authors.initials: LM
authors.lastname: Kauri
authors.affiliation: Air Health Science Division, Water and Air Quality Bureau, Health Canada, 269 Laurier Avenue W, Ottawa, ON K1A 0K9, Canada. Electronic address: Christine.Lemieux@hc-sc.gc.ca.
authors.forename: Christine L
authors.initials: CL
authors.lastname: Lemieux
authors.affiliation: Population Studies Division, Environmental Health Science & Research Bureau, Health Canada, 50 Columbine Driveway, Ottawa, ON K1A 0K9, Canada. Electronic address: christopher.hebbern@hc-sc.gc.ca.
authors.forename: Christopher
authors.initials: C
authors.lastname: Hebbern
authors.affiliation: Exposure and Biomonitoring Division, Environmental Health Science & Research Bureau, Health Canada, 50 Colombine Driveway, Ottawa, ON K1A 0K9, Canada. Electronic address: jiping.zhu@hc-sc.gc.ca.
authors.forename: Jiping
authors.initials: J
authors.lastname: Zhu
mesh_terms: D000393:Air Pollutants / Q000032:analysis*; D016902:Air Pollution, Indoor / Q000032:analysis / Q000706:statistics & numerical data; D002170:Canada / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006798:Housing / Q000706:statistics & numerical data; D006801:Humans; D019570:Inhalation Exposure / Q000032:analysis / Q000706:statistics & numerical data*; D008297:Male; D012129:Respiratory Function Tests; D012140:Respiratory Tract Diseases / Q000453:epidemiology; D014505:Urban Population; D055549:Volatile Organic Compounds / Q000032:analysis*
chemical_list: D000393:Air Pollutants; D055549:Volatile Organic Compounds
keywords: Air quality; Asthma; Indoor air; Pulmonary diseases; Volatile organic compounds