title: Molecular resonance tonsillectomy in children: comparative study over standard techniques in an 11-year study.
abstract: OBJECTIVE
  Learn the molecular resonance (MR) technology for tonsillectomy. An analysis of outcomes of MR compared to standard cold-knife (CK) and monopolar cautery (MPC) for pediatric tonsillectomy offers new possibilities, lowering postoperative morbidity.
  
  
  METHODS
  Eleven-year, prospective, randomized, 3-group trial.
  
  
  METHODS
  Tertiary care pediatric institution.
  
  
  METHODS
  Eight hundred and seventy-three children undergoing adenotonsillectomy were randomly assigned to MR (n = 283), CK (n = 279), or MPC (n = 279) techniques. Outcome measures included intraoperative time, blood loss, postoperative pain, weight loss, and histopathologic examination on excised tonsils.
  
  
  RESULTS
  Histopathologic evaluation revealed reduced thermal injury with MR over MPC (43 µm vs 186, P < .001), statistically associated with reduced muscular, blood vessel, and nerve fiber damage compared to CK (P < .001). Blood loss was minimal in MR. Significant reduced pain scores were related to MR (P < .002). Two MR, 15 CK, and 12 MPC patients experienced delayed bleeding.
  
  
  CONCLUSIONS
  MR for pediatric tonsillectomy resulted in reduced histopathologic thermal injury, lower pain scores, and reduced postoperative morbidity compared with CK and MPC techniques in an 11-year study.
authors.affiliation: Division of Pediatric Otolaryngology, Department of Otorhinolaryngology, Head and Neck Surgery, Vicenza Civil Hospital, Vicenza, Italy riccardo.deredita@ulssvicenza.it riccardo.deredita@hotmail.com.
authors.forename: Riccardo
authors.initials: R
authors.lastname: D'Eredità
mesh_terms: D000293:Adolescent; D002425:Cautery; D002648:Child; D002675:Child, Preschool; D003452:Cryosurgery; D005260:Female; D006801:Humans; D008297:Male; D014066:Palatine Tonsil / Q000473:pathology; D011446:Prospective Studies; D016037:Single-Blind Method; D013997:Time Factors; D014068:Tonsillectomy / Q000379:methods*
keywords: adenotonsillectomy; children; molecular resonance; prospective trial; tonsillectomy