title: A case control study investigating the effects of levels of physical activity at work as a risk factor for prostate cancer.
abstract: BACKGROUND
  A potential risk factor for prostate cancer is occupational physical activity. The occupational aetiology of prostate cancer remains unclear. The purpose of this research was to examine associations between the level of exposure to various measures of physical activity at work and the risk of Prostate Cancer.
  
  
  METHODS
  Using the Finnish Job Exposure Matrix and the occupational history of 1,436 cases and 1,349 matched controls from an Australian case control study; we investigated five related exposure variables considered to be risk factors by comparing odds ratios.
  
  
  RESULTS
  Modestly increasing odds ratios were detected with increasing levels of workload but there was no difference in this trend between moderate and high grade tumours. In regard to occupational physical workload no statistically significant association was observed overall but an increasing trend with level of exposure was observed for high grade compared with moderate grade tumours.
  
  
  CONCLUSIONS
  Both workload and physical workload merit further investigation, particularly for the latter in relation to grade of tumour.
authors.affiliation: Department of Epidemiology & Preventive Medicine, Monash University, The Alfred Centre, The Alfred, Commercial Road, Melbourne, Victoria 3004, Australia. 2doolans@vic.australis.com.au.
authors.forename: Glenn W
authors.initials: GW
authors.lastname: Doolan
authors.forename: Geza
authors.initials: G
authors.lastname: Benke
authors.forename: Graham G
authors.initials: GG
authors.lastname: Giles
authors.forename: Gianluca
authors.initials: G
authors.lastname: Severi
authors.forename: Timo
authors.initials: T
authors.lastname: Kauppinen
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D009517:New South Wales / Q000453:epidemiology; D009784:Occupational Diseases / Q000453:epidemiology* / Q000209:etiology; D011471:Prostatic Neoplasms / Q000453:epidemiology* / Q000209:etiology; D012307:Risk Factors; D014739:Victoria / Q000453:epidemiology; D014904:Western Australia / Q000453:epidemiology
references.citation: Nurs Forum. 2005 Jul-Sep;40(3):79-87
references.pmid: 16271119
references.citation: Am J Ind Med. 1998 Apr;33(4):409-17
references.pmid: 9513649
references.citation: Appl Occup Environ Hyg. 2001 Jan;16(1):84-91
references.pmid: 11202032
references.citation: Ann Oncol. 2001 Jun;12(6):761-5
references.pmid: 11484949
references.citation: Eur J Cancer Prev. 2008 Aug;17(4):336-9
references.pmid: 18562958
references.citation: Eur Urol. 2011 Nov;60(5):1029-44
references.pmid: 21802197
references.citation: Eur J Cancer Prev. 2007 Oct;16(5):415-21
references.pmid: 17923812
references.citation: J Am Geriatr Soc. 2009 Jan;57(1):24-30
references.pmid: 19054189
references.citation: IARC Sci Publ. 1987;(82):1-406
references.pmid: 3329634
references.citation: Cancer Causes Control. 2000 Sep;11(8):759-64
references.pmid: 11065013
references.citation: Int J Occup Environ Health. 2000 Jul-Sep;6(3):194-202
references.pmid: 10926723
references.citation: Am J Ind Med. 2007 Aug;50(8):568-76
references.pmid: 17620275
references.citation: Cancer Causes Control. 2008 Feb;19(1):107-14
references.pmid: 18064535
references.citation: BMJ. 2013 Feb 07;346:f165
references.pmid: 23393080
references.citation: Prostate. 2008 Apr 1;68(5):563-70
references.pmid: 18247399
references.citation: Scand J Work Environ Health. 2011 Jan;37(1):6-29
references.pmid: 20802979
references.citation: Br J Cancer. 1996 Nov;74(10):1682-6
references.pmid: 8932356
references.citation: Asian Pac J Cancer Prev. 2014;15(2):501-16
references.pmid: 24568454
references.citation: Ann Oncol. 2012 Jul;23(7):1665-71
references.pmid: 22228452
references.citation: Scand J Work Environ Health. 1995 Aug;21(4):265-71
references.pmid: 8553000
references.citation: Am J Prev Med. 2011 Apr;40(4):476-85
references.pmid: 21406284
references.citation: J Prev Med Hyg. 2011 Dec;52(4):174-80
references.pmid: 22442921