title: An umpolung approach toward N-aryl nitrone construction: a phosphine-mediated addition of 1,2-dicarbonyls to nitroso electrophiles.
abstract: An umpolung approach toward nitrone construction utilizing a phosphine-mediated addition of 1,2-dicarbonyls to nitroso compounds is reported. The reaction exhibits a high degree of chemoselectivity and provides direct access to isoxazolidines, imines, and trisubstituted alkenes.
authors.affiliation: Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, USA. bashfeld@nd.edu.
authors.forename: Aditi P
authors.initials: AP
authors.lastname: Chavannavar
authors.forename: Allen G
authors.initials: AG
authors.lastname: Oliver
authors.forename: Brandon L
authors.initials: BL
authors.lastname: Ashfeld