title: A local circadian clock calls time on lung inflammation.
abstract: Inflammatory diseases typically display circadian variation in symptom severity. A new study in mice shows how a pulmonary epithelial cell clock controls neutrophil recruitment to the lungs and provides insight into interactions between local and systemic circadian clocks.
authors.affiliation: Academic Unit of Respiratory Medicine, Department of Infection and Immunity, The Medical School, University of Sheffield, Sheffield, UK.
authors.forename: A A Roger
authors.initials: AA
authors.lastname: Thompson
authors.affiliation: Academic Unit of Respiratory Medicine, Department of Infection and Immunity, The Medical School, University of Sheffield, Sheffield, UK.
authors.forename: Sarah R
authors.initials: SR
authors.lastname: Walmsley
authors.affiliation: Academic Unit of Respiratory Medicine, Department of Infection and Immunity, The Medical School, University of Sheffield, Sheffield, UK.
authors.forename: Moira K B
authors.initials: MK
authors.lastname: Whyte
mesh_terms: D056930:ARNTL Transcription Factors / Q000276:immunology*; D000818:Animals; D054365:Chemokine CXCL5 / Q000276:immunology*; D057906:Circadian Clocks / Q000276:immunology*; D005938:Glucocorticoids / Q000494:pharmacology*; D006801:Humans; D011018:Pneumonia, Pneumococcal / Q000276:immunology*; D013296:Streptococcus pneumoniae
chemical_list: D056930:ARNTL Transcription Factors; C538961:Bmal1 protein, mouse; D054365:Chemokine CXCL5; C094739:Cxcl5 protein, mouse; D005938:Glucocorticoids
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