title: Genome evolution: How sister genes grow apart.
abstract: As genomes evolve, proteins with novel functions arise primarily from gene duplication and divergence events. A new study identifies several molecular mechanisms by which related transcription factors diverge over time to control new sets of target genes and novel cellular functions.
authors.affiliation: Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
authors.forename: Victoria M
authors.initials: VM
authors.lastname: Blake
authors.affiliation: Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Electronic address: sbarolo@umich.edu.
authors.forename: Scott
authors.initials: S
authors.lastname: Barolo
mesh_terms: D000818:Animals; D002176:Candida albicans / Q000235:genetics*; D019143:Evolution, Molecular; D020440:Gene Duplication; D005786:Gene Expression Regulation / Q000235:genetics*; D005800:Genes, Fungal / Q000235:genetics*; D006801:Humans; D014157:Transcription Factors / Q000235:genetics*
chemical_list: D014157:Transcription Factors