title: Anterior segment ischemia following diode laser photocoagulation for aggressive posterior retinopathy of prematurity.
abstract: OBJECTIVE
  To describe the clinical and demographical characteristics and treatment outcomes of the premature infants who were presented with the signs of anterior segment ischemia (ASI) following transpupillary diode laser photocoagulation for aggressive posterior retinopathy of prematurity (APROP).
  
  
  METHODS
  The records of the premature infants who developed ASI following bilateral laser photocoagulation between November 2010 and December 2013 in a single institution for the treatment of APROP were retrospectively reviewed. The clinical and demographical characteristics, laser parameters, anterior segment complications, and structural outcomes were evaluated.
  
  
  RESULTS
  Nine eyes of five infants (three males, two females) were recruited for the study. Mean gestational age (GA), birth weight (BW), and postmenstrual age (PMA) at the time of laser ablation were 28.2 ± 2.5 weeks, 1,287.0 ± 483.4 g and 34.8 ± 2.2 weeks, respectively. All eyes were treated with a near-confluent pattern of laser ablation. Several anterior segment complications were observed including corneal edema (nine eyes), posterior synechia (nine eyes), pupillary membranes (five eyes), shallow anterior chamber (three eyes), hyphema (three eyes), and focal lens opacities (two eyes), of all resolved completely. Permanent dense cataracts observed in two eyes of two infants who were scheduled for lensectomy and anterior vitrectomy. None of the eyes progressed to phthisis bulbi.
  
  
  CONCLUSIONS
  Anterior segment ischemia after laser treatment of APROP is a rarely encountered clinical entity. Mild and transient cases may resolve without any long-term sequelae but severe ones may progress to permanent cataract requiring further surgery.
authors.affiliation: Department Of Ophthalmology, Zeynep Kamil Maternity and Children's Disease Training and Research Hospital, Istanbul, Turkey, drmurat301@yahoo.com.tr.
authors.forename: Murat
authors.initials: M
authors.lastname: Gunay
authors.forename: Mehmet Ali
authors.initials: MA
authors.lastname: Sekeroglu
authors.forename: Gokhan
authors.initials: G
authors.lastname: Celik
authors.forename: Betul Onal
authors.initials: BO
authors.lastname: Gunay
authors.forename: Cihan
authors.initials: C
authors.lastname: Unlu
authors.forename: Fahri
authors.initials: F
authors.lastname: Ovali
mesh_terms: D000869:Anterior Eye Segment / Q000098:blood supply*; D001724:Birth Weight; D002386:Cataract / Q000209:etiology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007511:Ischemia / Q000209:etiology*; D017075:Laser Coagulation / Q000009:adverse effects*; D054023:Lasers, Semiconductor / Q000009:adverse effects*; D008297:Male; D012178:Retinopathy of Prematurity / Q000601:surgery*; D012189:Retrospective Studies; D012307:Risk Factors
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