title: Unusual relapse of primary central nervous system lymphoma at site of lumbar puncture.
abstract: Primary CNS lymphoma (PCNSL) is a rare non-Hodgkin's lymphoma confined to the CNS. Local relapse of this disease is common, but extracranial or subcutaneous metastasis is rare with only a few cases being reported in literature. We report a 63-year-old male patient, who responded well to treatment for PCNSL but relapsed two and half years later with a lumbosacral nodule at the site of a previous lumbar puncture due to microscopic tumor seeding. Clinicians treating patients with PCNSL must remain alert to the possibility of extracranial solitary relapse even after the resolution of initial disease because prompt treatment can result in a good outcome.
authors.affiliation: Dow Medical College, Dow University of Health Sciences, Baba-e-Urdu Road, Karachi 74200, Pakistan.
authors.forename: Zartaj
authors.identifier: 0000-0002-1648-7373
authors.initials: Z
authors.lastname: Ahmed
authors.affiliation: Virginia G Piper Cancer Centre, 10460 N. 92nd Street, Suite No. 200, Scottsdale, AZ 85258, USA.
authors.forename: Ramesh K
authors.initials: RK
authors.lastname: Ramanathan
authors.affiliation: Scottsdale Medical Imaging, 3501 N. Scottsdale Road No. 130, Scottsdale, AZ 85251, USA.
authors.forename: Sunil
authors.initials: S
authors.lastname: Ram
authors.affiliation: Scottsdale Pathology Associates, 9003 E. Shea Boulevard, Scottsdale, AZ 85260, USA.
authors.forename: James
authors.identifier: 0000-0003-3175-5409
authors.initials: J
authors.lastname: Newell
authors.affiliation: Palo Verde Cancer Centre, 10460 N. 92nd Street, Suite 402, Scottsdale, AZ 85258, USA.
authors.forename: Maqbool
authors.initials: M
authors.lastname: Halepota
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