title: Anorectal manometric parameters are influenced by gender and age in subjects with normal bowel function.
abstract: OBJECTIVE
  Anorectal manometry provides objective information about anorectal function, but its results depend on the examiner's skill, the type of equipment, and subject characteristics like age or gender. This single institution, prospective study was performed to investigate the effect of gender and age on the results of anorectal manometry.
  
  
  METHODS
  All included subjects completed a questionnaire to assess their bowel function. The survey included 13 validated questions (eight on constipation and five on incontinence) and was used to exclude subjects with pathological constipation or incontinence. Subjects with normal bowel function underwent anorectal manometry to measure anal sphincter length (ASL), maximum resting pressure (MRP), and maximum squeeze pressure (MSP), and the results were compared by gender and age.
  
  
  RESULTS
  The mean age of the 154 participants (94 male and 60 female) was 59.1 years. ASL was greater in men (4.23 vs. 3.85 cm, p < 0.001). MRP was not significantly different according to gender (p = 0.93), but MSP was higher in men (190.18 vs. 116.49 mmHg, p < 0.001). ASL did not correlate with age (p = 0.707). MRP was inversely related to age in both men (R (2) = 0.152, p < 0.001) and women (R (2) = 0.282, p < 0.001), and MSP only in women (R (2) = 0.210, p < 0.001).
  
  
  CONCLUSIONS
  Anorectal manometric parameters are influenced by gender and age. This should be taken into consideration when interpreting manometric readings in a clinical setting.
authors.affiliation: Department of Colorectal Clinic, Asan Medical Center, Seoul, South Korea.
authors.forename: Hyang Ran
authors.initials: HR
authors.lastname: Lee
authors.forename: Seok-Byung
authors.initials: SB
authors.lastname: Lim
authors.forename: Jeong Yun
authors.initials: JY
authors.lastname: Park
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001003:Anal Canal / Q000033:anatomy & histology / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D011312:Pressure; D011446:Prospective Studies; D012007:Rectum / Q000502:physiology*; D012016:Reference Values; D012737:Sex Factors
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