title: [Atypical fractures of the femur: apropos of 3 clinical cases].
abstract: Osteoporosis is an increasing public health problem. The bisphophonates are the most useful treatment used through the world to prevent osteoporotic fractures. Their large prescription revealed an unpredictable side effect: the atypical fracture. These fractures appear in the subtrochanteric or diaphysal femoral proximal site, spontaneously or after a low trauma, and could be bilateral. X-rays shows a transversal or oblique fracture with a spur in the cortex and with a diffuse thickening of the cortical of the proximal femur. Expert's recommendations are current in progress to well understand and managed this problem. Here we report three cases of atypical femur fractures occurred in our Centre of bone diseases with some management and treatment propositions.
authors.affiliation: Centre des maladies osseuses, Lausanne University Hospital.
authors.forename: Maria
authors.initials: M
authors.lastname: Sanduloviciu
authors.affiliation: Centre des maladies osseuses, Lausanne University Hospital.
authors.forename: Delphine
authors.initials: D
authors.lastname: Stoll
authors.affiliation: Centre des maladies osseuses, Lausanne University Hospital.
authors.forename: Olivier
authors.initials: O
authors.lastname: Lamy
authors.affiliation: Service de rhumatologie, Hôpitaux Fribourgeois.
authors.forename: Marc-Antoine
authors.initials: MA
authors.lastname: Krieg
authors.affiliation: Centre des maladies osseuses, Lausanne University Hospital.
authors.forename: Bérengère
authors.initials: B
authors.lastname: Aubry-Rozier
mesh_terms: D000368:Aged; D004164:Diphosphonates / Q000009:adverse effects* / Q000627:therapeutic use*; D057915:Drug Substitution; D005260:Female; D005264:Femoral Fractures / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000601:surgery; D005593:Fracture Fixation, Internal; D005594:Fracture Fixation, Intramedullary; D005598:Fractures, Spontaneous / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D015663:Osteoporosis, Postmenopausal / Q000517:prevention & control*; D011859:Radiography; D012307:Risk Factors
chemical_list: D004164:Diphosphonates
keywords: Bisphosphonate; Empfehlungen; Osteoporose; atypical fracture; atypische Frakturen; bisphosphonates; fractures atypiques; osteoporosis; ostéoporose; recommandations; recommendations