title: Carcinoma of unknown primary presenting as large right atrial and ventricular mass secondary to disseminated tumor thrombosis.
abstract: We report a 65-year-old male patient who presented with right heart failure and a large mobile right atrial and ventricular mass on echocardiography. His computed tomography demonstrated bilateral supraclavicular/mediastinal lymphadenopathy, right atrial and ventricular mass with right pulmonary artery segmental embolism, and multiple liver hypodense lesions. His tumor markers were negative. However, fine-needle aspiration cytology of supraclavicular lymph node revealed metastatic carcinoma suggestive of squamous cell carcinoma. He was suspected to have carcinoma of unknown primary origin. This case illustrates a rare presentation of carcinoma of unknown primary origin with disseminated tumor thrombosis primarily manifesting in heart and other sites.
authors.affiliation: Department of Cardiology, Royal Hospital, Muscat, Sultanate of Oman.
authors.forename: Prashanth
authors.initials: P
authors.lastname: Panduranga
authors.affiliation: Department of Cardiology, Royal Hospital, Muscat, Sultanate of Oman.
authors.forename: Zahid
authors.initials: Z
authors.lastname: Kazmi
authors.affiliation: Department of Cardiology, Royal Hospital, Muscat, Sultanate of Oman.
authors.forename: Najib
authors.initials: N
authors.lastname: Al-Rawahi
authors.affiliation: Department of Chest Medicine, Royal Hospital, Muscat, Sultanate of Oman.
authors.forename: Zulfikar
authors.initials: Z
authors.lastname: Habibulla
authors.affiliation: Department of Chest Medicine, Royal Hospital, Muscat, Sultanate of Oman.
authors.forename: Nabil
authors.initials: N
authors.lastname: Al-Lawati
authors.affiliation: Department of Radiology, Royal Hospital, Muscat, Sultanate of Oman.
authors.forename: Faiza
authors.initials: F
authors.lastname: Al-Kindi
keywords: Carcinoma of unknown primary; cardiac metastasis; right atrium; tumor thrombosis
references.citation: Ann Oncol. 2004 Mar;15(3):375-81
references.pmid: 14998838
references.citation: J Cardiovasc Med (Hagerstown). 2008 Aug;9(8):769-77
references.pmid: 18607239
references.citation: Rev Port Cardiol. 2009 May;28(5):633-9
references.pmid: 19650576