title: Development and matching of binocular orientation preference in mouse V1.
abstract: Eye-specific thalamic inputs converge in the primary visual cortex (V1) and form the basis of binocular vision. For normal binocular perceptions, such as depth and stereopsis, binocularly matched orientation preference between the two eyes is required. A critical period of binocular matching of orientation preference in mice during normal development is reported in literature. Using a reaction diffusion model we present the development of RF and orientation selectivity in mouse V1 and investigate the binocular orientation preference matching during the critical period. At the onset of the critical period the preferred orientations of the modeled cells are mostly mismatched in the two eyes and the mismatch decreases and reaches levels reported in juvenile mouse by the end of the critical period. At the end of critical period 39% of cells in binocular zone in our model cortex is orientation selective. In literature around 40% cortical cells are reported as orientation selective in mouse V1. The starting and the closing time for critical period determine the orientation preference alignment between the two eyes and orientation tuning in cortical cells. The absence of near neighbor interaction among cortical cells during the development of thalamo-cortical wiring causes a salt and pepper organization in the orientation preference map in mice. It also results in much lower % of orientation selective cells in mice as compared to ferrets and cats having organized orientation maps with pinwheels.
authors.affiliation: Electrical Engineering Department, Indian Institute of Technology Delhi New Delhi, India.
authors.forename: Basabi
authors.initials: B
authors.lastname: Bhaumik
authors.affiliation: Electrical Engineering Department, Indian Institute of Technology Delhi New Delhi, India.
authors.forename: Nishal P
authors.initials: NP
authors.lastname: Shah
keywords: critical period for orientation matching; mouse V1; orientation map; orientation selectivity; receptive field alignment
references.citation: J Neurosci. 2001 Sep 15;21(18):7293-302
references.pmid: 11549739
references.citation: Science. 1999 Jul 23;285(5427):599-604
references.pmid: 10417392
references.citation: Vision Res. 2004 Dec;44(28):3307-16
references.pmid: 15535998
references.citation: Nature. 1995 Nov 16;378(6554):281-4
references.pmid: 7477347
references.citation: J Neurosci. 2011 Aug 24;31(34):12339-50
references.pmid: 21865476
references.citation: J Neurophysiol. 2012 Jun;107(11):2937-49
references.pmid: 22402662
references.citation: J Neurosci. 1994 Jan;14(1):409-41
references.pmid: 8283248
references.citation: Curr Opin Neurobiol. 2014 Feb;24(1):95-102
references.pmid: 24492085
references.citation: Vis Neurosci. 2005 Sep-Oct;22(5):661-76
references.pmid: 16332277
references.citation: Annu Rev Neurosci. 2001;24:139-66
references.pmid: 11283308
references.citation: J Comput Neurosci. 2003 Mar-Apr;14(2):211-27
references.pmid: 12567018
references.citation: J Neurosci. 2007 Sep 5;27(36):9648-52
references.pmid: 17804625
references.citation: Cell. 2008 Oct 31;135(3):422-35
references.pmid: 18984155
references.citation: Cereb Cortex. 2014 Jun;24(6):1658-70
references.pmid: 23389996
references.citation: Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16261-6
references.pmid: 12461179
references.citation: Nature. 1996 Mar 21;380(6571):249-52
references.pmid: 8637573
references.citation: Curr Opin Neurobiol. 1996 Aug;6(4):475-80
references.pmid: 8794104
references.citation: Science. 2000 Mar 31;287(5462):2479-82
references.pmid: 10741966
references.citation: J Physiol. 1996 Aug 1;494 ( Pt 3):757-71
references.pmid: 8865072
references.citation: Neuron. 2005 Dec 8;48(5):797-809
references.pmid: 16337917
references.citation: Front Neural Circuits. 2013 Mar 25;7:28
references.pmid: 23533083
references.citation: Vis Neurosci. 2001 Nov-Dec;18(6):879-91
references.pmid: 12020078
references.citation: J Neurosci. 1997 Mar 15;17(6):2112-27
references.pmid: 9045738
references.citation: J Neurosci. 1993 Dec;13(12):5251-62
references.pmid: 8254372
references.citation: J Neurophysiol. 2002 Jul;88(1):507-13
references.pmid: 12091572
references.citation: Science. 1994 Jan 28;263(5146):532-6
references.pmid: 8290963
references.citation: Nat Neurosci. 2013 Jun;16(6):714-23
references.pmid: 23644484
references.citation: Nature. 2011 May 5;473(7345):87-91
references.pmid: 21478872
references.citation: Proc Natl Acad Sci U S A. 1989 Dec;86(23):9574-8
references.pmid: 2556718
references.citation: J Comp Neurol. 2006 Dec 20;499(6):861-81
references.pmid: 17072837
references.citation: J Neurophysiol. 1978 Jan;41(1):28-42
references.pmid: 621544
references.citation: J Neurosci. 2000 Mar 1;20(5):1922-30
references.pmid: 10684893
references.citation: J Physiol. 1962 Jan;160:106-54
references.pmid: 14449617
references.citation: Biol Cybern. 1993;69(2):109-18
references.pmid: 8373882
references.citation: J Physiol. 1968 Mar;195(1):215-43
references.pmid: 4966457
references.citation: J Neurophysiol. 2008 Oct;100(4):1936-48
references.pmid: 18667547
references.citation: Nat Rev Neurosci. 2001 Apr;2(4):251-62
references.pmid: 11283748
references.citation: Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3380-3
references.pmid: 9096402
references.citation: J Neurosci. 2012 Mar 21;32(12):4049-64
references.pmid: 22442071
references.citation: J Neurosci. 2013 Apr 24;33(17):7325-44
references.pmid: 23616540
references.citation: Neuron. 2008 Jun 26;58(6):851-8
references.pmid: 18579076
references.citation: Neuroscientist. 2007 Dec;13(6):639-56
references.pmid: 17911223
references.citation: Neuron. 2000 Dec;28(3):955-66
references.pmid: 11163279
references.citation: Nature. 2013 Apr 4;496(7443):96-100
references.pmid: 23552948
references.citation: J Neurosci. 1999 Mar 15;19(6):1976-87
references.pmid: 10066251
references.citation: J Comp Neurol. 1975 Apr 1;160(3):269-90
references.pmid: 1112925
references.citation: J Comp Neurol. 1988 Aug 22;274(4):539-59
references.pmid: 2464623
references.citation: Science. 1992 Nov 6;258(5084):1007-11
references.pmid: 1279803
references.citation: Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):15049-54
references.pmid: 19706480
references.citation: J Neurosci. 2004 Sep 29;24(39):8459-69
references.pmid: 15456819
references.citation: Neuron. 2012 Jul 26;75(2):230-49
references.pmid: 22841309
references.citation: J Neurosci. 1991 Jul;11(7):1959-79
references.pmid: 2066770
references.citation: J Comp Neurol. 1994 Jun 22;344(4):581-97
references.pmid: 7929893
references.citation: Nature. 1997 Apr 17;386(6626):680-5
references.pmid: 9109486
references.citation: J Neurophysiol. 2003 Dec;90(6):3594-607
references.pmid: 12944530
references.citation: Neuron. 2000 Sep;27(3):427-30
references.pmid: 11055425
references.citation: J Neurosci. 1996 Nov 15;16(22):7253-69
references.pmid: 8929433
references.citation: J Neurophysiol. 1998 Jan;79(1):13-20
references.pmid: 9425172
references.citation: Science. 1996 Nov 15;274(5290):1133-8
references.pmid: 8895456
references.citation: J Neurosci. 2000 May 1;20(9):3233-43
references.pmid: 10777788
references.citation: Front Neuroanat. 2011 Sep 28;5:62
references.pmid: 22046148
references.citation: Neuron. 1995 Mar;14(3):599-605
references.pmid: 7695906
references.citation: Brain Res Rev. 2009 May;60(2):287-305
references.pmid: 19162072
references.citation: Nature. 2001 Jun 28;411(6841):1049-52
references.pmid: 11429605
references.citation: Neuron. 2003 Dec 18;40(6):1161-72
references.pmid: 14687550
references.citation: Proc Natl Acad Sci U S A. 1989 Oct;86(20):8113-7
references.pmid: 2813381
references.citation: Neuron. 2006 Aug 3;51(3):339-49
references.pmid: 16880128
references.citation: Curr Opin Neurobiol. 1996 Feb;6(1):119-26
references.pmid: 8794047
references.citation: J Comp Neurol. 2010 Jun 1;518(11):2051-70
references.pmid: 20394058
references.citation: Neuron. 2010 Jan 28;65(2):246-56
references.pmid: 20152130
references.citation: Neuroscience. 2009 Jun 30;161(2):561-71
references.pmid: 19327388
references.citation: J Comp Neurol. 1990 Dec 22;302(4):920-34
references.pmid: 2081821
references.citation: PLoS One. 2011;6(10):e24997
references.pmid: 22022370
references.citation: Front Syst Neurosci. 2013 Nov 15;7:87
references.pmid: 24298241
references.citation: J Neurosci. 2008 Jul 23;28(30):7520-36
references.pmid: 18650330
references.citation: J Neurosci. 2010 Apr 28;30(17):5912-26
references.pmid: 20427651
references.citation: Neuron. 2001 Aug 30;31(4):569-80
references.pmid: 11545716
references.citation: J Neurosci. 1995 Aug;15(8):5448-65
references.pmid: 7643194
references.citation: Neuron. 2001 Feb;29(2):519-27
references.pmid: 11239440
references.citation: Nat Rev Neurosci. 2011 Jun;12(6):311-26
references.pmid: 21587288
references.citation: Invest Ophthalmol. 1972 May;11(5):346-54
references.pmid: 5028231
references.citation: J Physiol. 1972 Nov;226(3):725-49
references.pmid: 4564896
references.citation: Nature. 2012 Oct 11;490(7419):219-25
references.pmid: 23060192
references.citation: Annu Rev Neurosci. 1996;19:289-317
references.pmid: 8833445
references.citation: J Physiol. 1963 Mar;165:559-68
references.pmid: 13955384
references.citation: Annu Rev Neurosci. 2008;31:479-509
references.pmid: 18558864
references.citation: Curr Opin Neurobiol. 2007 Aug;17(4):401-7
references.pmid: 17720489
references.citation: Prog Neurobiol. 1996 May;49(1):53-71
references.pmid: 8817698
references.citation: J Neurosci. 2011 Dec 14;31(50):18506-21
references.pmid: 22171051
references.citation: J Comp Neurol. 1980 Sep 1;193(1):203-22
references.pmid: 6776165
references.citation: Nature. 1997 Jul 17;388(6639):279-84
references.pmid: 9230437
references.citation: Exp Brain Res. 1988;69(3):594-612
references.pmid: 3371440
references.citation: Curr Opin Neurobiol. 2003 Aug;13(4):413-20
references.pmid: 12965287
references.citation: Synapse. 1989;4(2):132-42
references.pmid: 2781465
references.citation: Nature. 1997 May 15;387(6630):281-4
references.pmid: 9153392