title: The value of the ucN13-P15 interpeak latency predicted acute posterior circulation ischemia and the chronic outcome.
abstract: OBJECTIVE
  To determine the sensitivity and specificity of the ucN13-P15 (CV2-Fz) and IcN13-P15 (CV7-Fz) interpeak latencies when used to predict acute posterior circulation ischemia.
  
  
  METHODS
  A total of 426 consecutive patients who were hospitalized within 3 days of the onset of stroke were prospectively enrolled in the study. Of these patients, 110 had infarct lesions in the posterior circulation territory. The ucN13-P15 and IcN13-P15 interpeak latencies on admission were assessed, and the chronic outcome was assessed at 3 months.
  
  
  RESULTS
  The ucN13-P15 and IcN13-P15 interpeak latencies (both P < 0.001) were prolonged in patients with posterior circulation ischemia than in those with anterior circulation ischemia. The optimal cutoff score of the baseline ucN13-P15 IPL (≥ 3.35 milliseconds) had a sensitivity of 76.8% and a specificity of 79.9%. The IcN13-P15 IPL (≥ 4.225 milliseconds) had a sensitivity of 56.1% and a specificity of 93.2%.
  
  
  CONCLUSIONS
  The ucN13-P15 interpeak latency must be appraised in light of its diagnostic value in acute posterior circulation ischemia. However, the ucN13-P15 interpeak latency was not independently predictive of a favorable outcome.
authors.affiliation: Departments of *Electrophysiology and Neurology, First Affiliated Hospital of Herbing Medical University, Ha E Bing China.
authors.forename: Chao
authors.initials: C
authors.lastname: Peng
authors.forename: Xi
authors.initials: X
authors.lastname: Wang
authors.forename: Chaoming
authors.initials: C
authors.lastname: He
authors.forename: Yue
authors.initials: Y
authors.lastname: Ma
authors.forename: Shurong
authors.initials: S
authors.lastname: Duan
authors.forename: Xiqin
authors.initials: X
authors.lastname: Guan
authors.forename: Desheng
authors.initials: D
authors.lastname: Wang
authors.forename: Ying
authors.initials: Y
authors.lastname: Tang
mesh_terms: D000328:Adult; D020520:Brain Infarction / Q000175:diagnosis / Q000209:etiology*; D015331:Cohort Studies; D004558:Electric Stimulation; D004569:Electroencephalography; D004576:Electromyography; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008475:Median Nerve / Q000503:physiopathology; D008875:Middle Aged; D011237:Predictive Value of Tests; D012372:ROC Curve; D011930:Reaction Time / Q000502:physiology*; D012307:Risk Factors; D012720:Severity of Illness Index; D020521:Stroke / Q000150:complications* / Q000175:diagnosis*