title: HuR and post-transcriptional regulation in vascular aging.
abstract: HuR (ELAV11 (embryonic lethal, abnormal vision)-like 1), a ubiquitously expressed member of the ELAV-like RNA-binding protein family, has been shown to regulate the stability and translation of mRNAs that encode factors regulating cellular senescence, thereby impacting on aging. In this review, we discuss the current knowledge of HuR's role in vascular cell senescence and vascular aging.
authors.affiliation: Research Center on Aging, Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, 100191, China, wwg@bjmu.edu.cn.
authors.forename: WenGong
authors.initials: W
authors.lastname: Wang
mesh_terms: D001808:Blood Vessels / Q000166:cytology*; D016922:Cellular Senescence / Q000235:genetics*; D051959:ELAV Proteins / Q000235:genetics / Q000502:physiology*; D006801:Humans; D012323:RNA Processing, Post-Transcriptional
chemical_list: D051959:ELAV Proteins