title: Applicability of the Chinese version of the 16-item Prodromal Questionnaire (CPQ-16) for identifying attenuated psychosis syndrome in a college population.
abstract: The aim of this study was to examine the reliability, validity, sensitivity and specificity of the Chinese version of the 16-item Prodromal Questionnaire (CPQ-16) for identifying attenuated psychosis syndrome (APS) in a college population.
  
  
  
  The participants were recruited from a university. Five hundred seventy-nine students completed the CPQ-16 and the Symptom Checklist-90. One class (n = 79) was randomly selected to be retested with the CPQ-16 after 2 weeks. A randomly selected group of 49 individuals who tested positive and 50 individuals who tested negative were interviewed using the Structured Interview for Prodromal Syndromes (SIPS).
  
  
  
  The internal consistency reliability was good (Cronbach's α = 0.72). The test-retest reliability was 0.88. The total score on the CPQ-16 was moderately to highly correlated with the total score on the Symptom Checklist-90 and all of the subscales (r = 0.39-0.67, P < 0.001). A cut-off CPQ-16 score of 9 was used to differentiate between those with a APS diagnosis on the SIPS versus those with no SIPS diagnoses; this cut-off value yielded 85% sensitivity, 87% specificity, a positive predictive value of 63% and a positive likelihood ratio of 6.69. The area under the ROC curve (AUC) was significant for the CPQ-16 total score (AUC = 0.93, SE = 0.026, 95% CI = 0.87-0.98, P < 0.001). Based on the proposed cut-off score, the CPQ-16 yielded a positive rate of 5.0% (29/579).
  
  
  
  The CPQ-16, administered in a face-to-face interview, demonstrated high reliability and the ability to identify college students at risk for psychosis.
authors.affiliation: Department of Psychiatry, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
authors.forename: Fazhan
authors.initials: F
authors.lastname: Chen
authors.affiliation: Department of Psychosomatic Medicine, East Hospital, Tongji University School of Medicine, Shanghai, China.
authors.forename: Lu
authors.initials: L
authors.lastname: Wang
authors.affiliation: Department of Psychosomatic Medicine, East Hospital, Tongji University School of Medicine, Shanghai, China.
authors.forename: Jikun
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Psychiatry, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
authors.forename: Anisha
authors.initials: A
authors.lastname: Heeramun-Aubeeluck
authors.affiliation: Department of Psychosomatic Medicine, East Hospital, Tongji University School of Medicine, Shanghai, China.
authors.forename: Jiabei
authors.initials: J
authors.lastname: Yuan
authors.affiliation: Department of Psychosomatic Medicine, East Hospital, Tongji University School of Medicine, Shanghai, China.|Faculty of Humanities and Behavioral Medicine, Tongji University School of Medicine, Shanghai, China.
authors.forename: Xudong
authors.initials: X
authors.lastname: Zhao
mesh_terms: D000293:Adolescent; D044466:Asian People / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D062706:Prodromal Symptoms; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data*; D011594:Psychometrics; D011618:Psychotic Disorders / Q000175:diagnosis*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013334:Students / Q000523:psychology; D014495:Universities; D055815:Young Adult
keywords: China; Chinese version of the 16-item Prodromal Questionnaire (CPQ-16); attenuated psychosis syndrome