title: Evaluation of clinical factors influencing pregnancy rate in frozen embryo transfer.
abstract: BACKGROUND
  Frozen embryo transfer (FET) is one of the most important supplementary procedures in the treatment of infertile couples. While general information concerning the outcome of fresh embryo transfer has been documented, paucity of investigations has addressed the clinical factors influenced on pregnancy rates in FET.
  
  
  OBJECTIVE
  In this study, we performed a retrospective analysis of clinical factors that potentially influence the outcome of FET.
  
  
  METHODS
  We reviewed the data from 372 women who were subjected to FET registered from April 2009-2011 at the Research and clinical center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Baseline data and pregnancy rate were collected. The data were analyzed statistically using the Kolmogorov-Smirnov, and Mann-Whitney tests.
  
  
  RESULTS
  The clinical pregnancy rate was 57.7 and 29.2% in women <35 years old, and women >35 years old, respectively (p<0.0001). Clinical pregnancy rates in women with FSH <10 IU/ml, and FSH >10 IU/ml were 56.3% and 17.5 %, respectively (p<0.0001). Whereas the other clinical parameters consist of reason of fetus freezing, primary IVF protocol, IVF procedure, endometrial thickness, treatment duration to fetal transfer found to be unrelated to FET outcomes (p>0.05).
  
  
  CONCLUSIONS
  Female age and basal FSH level are the most important factors influencing the clinical pregnancy rate following FET.
authors.affiliation: Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Eftekhar
authors.affiliation: Department of Obstetrics and Gynecology, Bushehr University of Medical Science, Bushehr, Iran.
authors.forename: Elham
authors.initials: E
authors.lastname: Rahmani
authors.affiliation: Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
authors.forename: Soheila
authors.initials: S
authors.lastname: Pourmasumi
keywords: Clinical pregnancy rate; Frozen embryo transfer; In Vitro Fertilization
references.citation: Reprod Biomed Online. 2006 Sep;13(3):321-5
references.pmid: 16984757
references.citation: Fertil Steril. 1994 Oct;62(4):775-80
references.pmid: 7926086
references.citation: Hum Reprod. 2001 Jun;16(6):1140-4
references.pmid: 11387283
references.citation: Fertil Steril. 2009 Oct;92(4):1269-1275
references.pmid: 18930194
references.citation: Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2012 Dec;37(12):1233-8
references.pmid: 23281376
references.citation: Fertil Steril. 2004 May;81(5):1399-400
references.pmid: 15136111
references.citation: J Ovarian Res. 2008 Nov 06;1(1):7
references.pmid: 19014420
references.citation: Reprod Biomed Online. 2006 Oct;13(4):516-22
references.pmid: 17007672
references.citation: Reprod Biomed Online. 2007 Feb;14(2):148-54
references.pmid: 17298715
references.citation: Fertil Steril. 1984 Aug;42(2):293-6
references.pmid: 6745463
references.citation: Fertil Steril. 1996 Jan;65(1):103-8
references.pmid: 8557122
references.citation: Hum Reprod. 1999 Oct;14(10):2619-24
references.pmid: 10527997
references.citation: Fertil Steril. 2008 Oct;90(4):1294-6
references.pmid: 18178197
references.citation: Taiwan J Obstet Gynecol. 2011 Jun;50(2):159-64
references.pmid: 21791301
references.citation: Hum Reprod. 2009 Jun;24(6):1267-87
references.pmid: 19225009
references.citation: Ann N Y Acad Sci. 2011 Mar;1221:32-9
references.pmid: 21401627
references.citation: Fertil Steril. 2013 Jan;99(1):168-173
references.pmid: 23025881
references.citation: Fertil Steril. 1995 Jul;64(1):22-8
references.pmid: 7789569
references.citation: J Med Assoc Thai. 1996 Jun;79(6):347-52
references.pmid: 8855607
references.citation: Cochrane Database Syst Rev. 2010 Jan 20;(1):CD006359
references.pmid: 20091592
references.citation: Hum Reprod. 2000 Jan;15(1):175-9
references.pmid: 10611209
references.citation: Hum Reprod. 2006 Sep;21(9):2368-74
references.pmid: 16684837
references.citation: Zhonghua Fu Chan Ke Za Zhi. 2001 May;36(5):290-2
references.pmid: 11783380
references.citation: J Assist Reprod Genet. 1998 Aug;15(7):431-7
references.pmid: 9717119
references.citation: J Assist Reprod Genet. 1996 Apr;13(4):293-7
references.pmid: 8777342
references.citation: Fertil Steril. 1994 Dec;62(6):1192-6
references.pmid: 7957983
references.citation: Hum Reprod. 2001 Nov;16(11):2316-9
references.pmid: 11679511
references.citation: Clin Exp Obstet Gynecol. 2008;35(1):13-5
references.pmid: 18390073
references.citation: Hum Reprod. 2001 Jul;16(7):1403-8
references.pmid: 11425820
references.citation: J Assist Reprod Genet. 2004 Dec;21(12):437-43
references.pmid: 15704519
references.citation: Fertil Steril. 2002 Jul;78(1):201-3
references.pmid: 12095518
references.citation: Fertil Steril. 1993 May;59(5):1070-4
references.pmid: 8486176
references.citation: Clin Exp Obstet Gynecol. 2008;35(3):167-9
references.pmid: 18754283
references.citation: Fertil Steril. 2008 Apr;89(4):832-9
references.pmid: 17681313
references.citation: Fertil Steril. 2002 May;77(5):956-60
references.pmid: 12009350
references.citation: Gynecol Endocrinol. 2005 Oct;21(4):227-31
references.pmid: 16316845
references.citation: Mol Cell Endocrinol. 2000 Nov 27;169(1-2):73-7
references.pmid: 11155958
references.citation: Zhonghua Yi Xue Za Zhi. 2009 Nov 10;89(41):2928-30
references.pmid: 20137652
references.citation: Nature. 1983 Oct 20-26;305(5936):707-9
references.pmid: 6633637