title: [A case of acute aortic dissection presenting with cerebral ischemic symptoms: utility of 3D CT angiography and CT perfusion for the diagnosis of acute stroke].
abstract: A 76-year-old woman presented at our hospital complaining of loss of consciousness, dysarthria, and upper extremity paresis. Head CT showed no remarkable findings. 3D CT angiography (CTA) and CT perfusion (CTP) revealed acute aortic dissection (AAD) involving the innominate artery and decreased cerebral blood flow in the right cerebral hemisphere, although there were no clinical signs of AAD. The patient underwent emergency allograft replacement performed by cardiovascular surgeons. The symptoms disappeared within several days and no cerebral infarction developed. Although patients with AAD and neurological symptoms can show a fatal course when they receive tissue plasminogen activator (tPA), it is difficult to exclude patient with AAD as candidates for tPA treatment. Routine use of 3D CTA and CTP in the diagnosis of acute stroke may help overcome the above problem.
authors.affiliation: Department of Neurosurgery, Tokyo Women's Medical University Medical Center East.
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Koseki
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Kuroi
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Arai
authors.forename: Hidenori
authors.initials: H
authors.lastname: Ohbuchi
authors.forename: Kengo
authors.initials: K
authors.lastname: Hirota
authors.forename: Shinji
authors.initials: S
authors.lastname: Hagiwara
authors.forename: Shigeru
authors.initials: S
authors.lastname: Tani
authors.forename: Atsushi
authors.initials: A
authors.lastname: Sasahara
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Kasuya
mesh_terms: D000368:Aged; D000792:Angiography / Q000379:methods; D001011:Aorta / Q000601:surgery; D002545:Brain Ischemia / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery*; D002560:Cerebrovascular Circulation / Q000187:drug effects; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D021621:Imaging, Three-Dimensional; D020521:Stroke / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery*; D015912:Thrombolytic Therapy / Q000379:methods; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator