title: The association between vibration and vascular injury in rheumatic diseases: a review of the literature.
abstract: Vascular manifestations can be seen early in the pathogenesis of inflammatory rheumatic diseases. Animal experiments, laboratory and clinical findings indicated that acute or long-term vibration exposure can induce vascular abnormalities. Recent years, in addition to Raynaud's phenomenon (RP), vibration as a risk factor for other rheumatic diseases has also received corresponding considered. This review is concentrated upon the role of vibration in the disease of systemic sclerosis (SSc). In this review, we are going to discuss the main mechanisms which are thought to be important in pathophysiology of vascular injury under the three broad headings of "vascular", "neural" and "intravascular". Aspects on the vibration and vascular inflammation are briefly discussed. And the epidemiological studies related to vibration studies in SSc and other rheumatic diseases are taken into account.
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University , Hefei , China .
authors.forename: Yu-Jie
authors.initials: YJ
authors.lastname: Wang
authors.forename: Xiao-Lei
authors.initials: XL
authors.lastname: Huang
authors.forename: Jun-Wei
authors.initials: JW
authors.lastname: Yan
authors.forename: Ya-Nan
authors.initials: YN
authors.lastname: Wan
authors.forename: Bing-Xiang
authors.initials: BX
authors.lastname: Wang
authors.forename: Jin-Hui
authors.initials: JH
authors.lastname: Tao
authors.forename: Bing
authors.initials: B
authors.lastname: Chen
authors.forename: Bao-Zhu
authors.initials: BZ
authors.lastname: Li
authors.forename: Guo-Jun
authors.initials: GJ
authors.lastname: Yang
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
mesh_terms: D042501:Angiogenic Proteins / Q000378:metabolism; D001172:Arthritis, Rheumatoid / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D001779:Blood Coagulation Factors / Q000378:metabolism; D016022:Case-Control Studies; D006801:Humans; D055806:Microvessels / Q000293:injuries / Q000378:metabolism / Q000473:pathology; D009784:Occupational Diseases / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D011928:Raynaud Disease / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D012595:Scleroderma, Systemic / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D057772:Vascular System Injuries / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D014732:Vibration / Q000009:adverse effects*
chemical_list: D042501:Angiogenic Proteins; D001779:Blood Coagulation Factors
keywords: Epidemiology; inflammation; rheumatic diseases; vasculopathy; vibration