title: An efficient strategy to syntheses of isoflavones.
abstract: Isoflavones were synthesized by two steps in good yields, starting from commercially available 2-hydroxyacetophenones and benzene analogs. First, intermediate 3-(dimethylamino)-1-(2-hydroxyphenyl) prop-2-en-1-ones were obtained by the condensation of 2-hydroxyacetophenones and DMF-DMA in DMF with high yields. Second, isoflavones were synthesized by irradiation of 3-(dimethylamino)-1-(2-hydroxyphenyl)prop- 2-en-1-ones in the presence of iodine using benzene analogs as solvent under a mercury lamp.
authors.affiliation: Key Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China, and School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, People's Republic of China.
authors.forename: Longzhu
authors.initials: L
authors.lastname: Liu
authors.forename: Qiuya
authors.initials: Q
authors.lastname: Wang
authors.forename: Zunting
authors.initials: Z
authors.lastname: Zhang
authors.forename: Qiong
authors.initials: Q
authors.lastname: Zhang
authors.forename: Zichao
authors.initials: Z
authors.lastname: Du
authors.forename: Dong
authors.initials: D
authors.lastname: Xue
authors.forename: Tingting
authors.initials: T
authors.lastname: Wang
mesh_terms: D007529:Isoflavones / Q000138:chemical synthesis*; D015394:Molecular Structure; D055668:Photochemical Processes
chemical_list: D007529:Isoflavones
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