title: Extraction of p-coumaric acid and ferulic acid using surfactant-based aqueous two-phase system.
abstract: Ferulic acid (FA) and p-coumaric acid (pCA) are high-value products that can be obtained by alkaline hydrolysis of lignocellulose. Present work explores the potential of surfactant-based cloud-point extraction (CPE) for FA and pCA extraction from corn cob hydrolysate. More than 90 % (w/w) extraction of both FA and pCA was achieved from model system with L92. The partition coefficient of FA and pCA in L92 aqueous phase system was 35 and 55, respectively. A significant enrichment (8-10-fold) of both FA and pCA was achieved in surfactant-rich phase. Furthermore, the downstream process volume was reduced by 10 to 13 times. Optimized conditions (5 % v/v L92 and pH 3.0) resulted into 85 and 89 % extraction of FA and p-CA, respectively, from alkaline corn cob hydrolysate. Biocompatibility tests were carried out for L92 for ethanol fermentation and found to be biocompatible. Thus, the new surfactant-based CPE system not only concentrated FA and pCA but also reduced the process volume significantly. Further, aqueous phase containing sugars can be used for ethanol fermentation.
authors.affiliation: Department of Chemical Engineering, Birla Institute of Technology and Science, Pilani Hyderabad Campus, R.R. District, Hyderabad, 500078, Telangana, India, pradipdhamole@gmail.com.
authors.forename: Pradip B
authors.initials: PB
authors.lastname: Dhamole
authors.forename: Dhanashree
authors.initials: D
authors.lastname: Demanna
authors.forename: S A
authors.initials: SA
authors.lastname: Desai
mesh_terms: D001672:Biocompatible Materials; D003373:Coumaric Acids / Q000302:isolation & purification*; D005285:Fermentation; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D011422:Propionates; D013501:Surface-Active Agents / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D003373:Coumaric Acids; D011422:Propionates; D013501:Surface-Active Agents; D014867:Water; C004999:ferulic acid; C495469:p-coumaric acid