title: [Cardiovascular exercise on obese women: effects on adiponectine, leptine, and tumour necrosis factor-alpha].
abstract: BACKGROUND
  The relationship of hormones adiponectin, leptin and tumor necrosis factor-alpha in adipose tissue on the atherogenic process is one of the most promising models in preventive medicine. The numerous tests performed to identify the effect of exercise on these hormones have not been clear on the type of exercise routine and physical effort calculated to contribute to changing plasma concentrations in obese women.
  
  
  OBJECTIVE
  Analyze controlledcardiovascular exercise effect on serum level of adiponectin, leptin, and tumournecrosis factor-alpha in obese young women.
  
  
  METHODS
  A simple blind clinical essay. The intervention covered a 10-week controlled, cardiovascular exercise program by 34 women (cases n=17, controls n=17) with a body mass index>27kg/m(2). Molecular analysis was performed by immune-fluorescence.
  
  
  RESULTS
  Following the intervention, cases and controls means were as follows: adiponectin 19.0 vs. 12.2μ/ml (P=.008); leptin 20.0 vs. 28.0μ/L (P=.02); and tumour necrosis factor-alpha 4.7 vs. 5.1pg/ml (P=.05).
  
  
  CONCLUSIONS
  The established exercise (5 sessions a week of exercise of 40min each for 10 weeks with a heart rate reserve of 40 to 80%) improved plasma concentrations of these hormones in the expected direction. This finding highlights an unpublished amount of exercise, controlled by the reserve cardiac frequency that might contribute the cardiovascular and metabolic protection to obese women.
authors.affiliation: Facultad de Enfermería, Benemérita Universidad Autónoma de Puebla, Puebla, México. Electronic address: nursingresearch@outlook.com.
authors.forename: Erick
authors.initials: E
authors.lastname: Landeros-Olvera
authors.affiliation: Dirección de investigación, Hospital General de México Dr. Eduardo Liceaga, México DF, México.
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: López-Alvarenga
authors.affiliation: Facultad de Salud Pública y Nutrición, Universidad Autónoma de Nuevo León, Nuevo León, Monterrey, México.
authors.forename: Edna J
authors.initials: EJ
authors.lastname: Nava-González
authors.affiliation: Facultad de Enfermería, Universidad Autónoma de Nuevo León, Nuevo León, Monterrey, México.
authors.forename: Esther
authors.initials: E
authors.lastname: Gallegos-Cabriales
authors.affiliation: Hospital Universitario de la Universidad Autónoma de Nuevo León, Nuevo León, Monterrey, México.
authors.forename: Fernando
authors.initials: F
authors.lastname: Lavalle-González
authors.affiliation: Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, Estados Unidos.
authors.forename: Raúl A
authors.initials: RA
authors.lastname: Bastarrachea
authors.affiliation: Facultad de Enfermería, Universidad Autónoma de Nuevo León, Nuevo León, Monterrey, México.
authors.forename: Bertha Cecilia
authors.initials: BC
authors.lastname: Salazar González
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000293:Adolescent; D015444:Exercise; D005260:Female; D006339:Heart Rate; D006801:Humans; D020738:Leptin / Q000097:blood*; D009765:Obesity / Q000097:blood*; D016037:Single-Blind Method; D014409:Tumor Necrosis Factor-alpha / Q000097:blood*; D055815:Young Adult
chemical_list: D052242:Adiponectin; D020738:Leptin; D014409:Tumor Necrosis Factor-alpha
keywords: Adiponectin; Adiponectina; Ejercicio; Exercise; Factor de necrosis tumoral-alfa; Leptin; Leptina; Mexico; México; Obesidad; Obesity; Tumour necrosis factor-alpha