title: 8-year follow-up of central giant cell lesion mimicking apical periodontitis.
abstract: BACKGROUND
  Lesions of nonendodontic origin may mimic apical periodontitis. Central giant cell lesions (CGCLs) are aggressive or nonaggressive benign idiopathic intraosseous lesions of the jaw. This report describes a case of a CGCL in the periapical region of teeth #21-#26 of a 17-year-old female who sought orthodontic care because of a change in the position of tooth #23.
  
  
  METHODS
  Clinical examination revealed mild facial asymmetry caused by increased volume in the mental region and cortical bone expansion but no cortical disruption. A panoramic radiograph showed a well-defined radiolucent osteolytic lesion involving teeth #21-#26. The cortical bone was not affected, and there was no root resorption. Incisional biopsy was performed, and the diagnosis was a CGCL. The lesion was enucleated surgically. CGCLs should be included in the differential diagnosis of jaw lesions that mimic apical periodontitis.
  
  
  RESULTS
  The patient subsequently underwent orthodontic treatment successfully.
  
  
  CONCLUSIONS
  The 8-year clinical and radiographic follow-up confirmed lesion remission, no recurrence, and pulp vitality of all teeth.
authors.affiliation: Department of Oral Sciences, University of Cuiabá, MT, Brazil; Cancer Hospital, Cuiabá, Mato Grosso, Brazil. Electronic address: arturaburad@gmail.com.
authors.forename: Artur Aburad
authors.initials: AA
authors.lastname: de Carvalhosa
authors.affiliation: Department of Oral Sciences, University of Cuiabá, MT, Brazil.
authors.forename: Regina Maria Cristovan
authors.initials: RM
authors.lastname: Zandonade
authors.affiliation: Cancer Hospital, Cuiabá, Mato Grosso, Brazil.
authors.lastname: de Souza Castro
authors.affiliation: Department of Oral Sciences, University of Cuiabá, MT, Brazil.
authors.forename: Cyntia Rodrigues
authors.initials: CR
authors.lastname: de Araújo Estrela
authors.affiliation: Department of Oral Sciences, University of Cuiabá, MT, Brazil.
authors.forename: Alvaro Henrique
authors.initials: AH
authors.lastname: Borges
authors.affiliation: Federal University of Goiás, Goiânia, Goiás, Brazil.
authors.forename: Carlos
authors.initials: C
authors.lastname: Estrela
mesh_terms: D000293:Adolescent; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006101:Granuloma, Giant Cell / Q000175:diagnosis*; D006801:Humans; D008336:Mandibular Diseases / Q000175:diagnosis*; D010485:Periapical Periodontitis / Q000175:diagnosis*; D011862:Radiography, Panoramic
keywords: Apical periodontitis; central giant cell lesion; differential diagnosis; periapical lesion