title: Long-term follow-up results in patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stents: results from a single high-volume PCI centre.
abstract: OBJECTIVE
  To assess both short-term and long-term prognosis in consecutive patients with coronary heart disease treated with drug-eluting stents in a high-volume percutaneous coronary intervention (PCI) centre.
  
  
  METHODS
  Observational cohort study.
  
  
  METHODS
  A hospital in the Henan province, China, between 2009 and 2011.
  
  
  METHODS
  A total of 2533 patients were enrolled. Patients with ST-elevation myocardial infarction (STEMI) treated with urgent PCI accounted for 3.9% of cases; patients with STEMI treated with delayed PCI accounted for 20.5% of cases; patients with stable angina accounted for 16.5% of cases; and patients with non-ST elevation acute coronary syndrome (NSTE-ACS) accounted for 58.6% of cases.
  
  
  METHODS
  Death, major adverse cardiac and cerebrovascular events (MACCE: death/myocardial infarction/stroke), and target vessel revascularisation.
  
  
  RESULTS
  Follow-up after a median of 29.8 months was obtained for 2533 patients (92.6%). The mortality rate during hospitalisation was highest in the urgent PCI group (p<0.001). During follow-up, although the incidences of death and MACCE were highest in the urgent PCI group, no significant differences were observed among the different groups. The incidences of cardiac death and myocardial infarction were significantly higher in the paclitaxel-eluting stent (PES) group than in the sirolimus-eluting stent (SES) group. Independent predictors of death during follow-up were age, left ventricular ejection function <40%, diabetes mellitus, prior coronary artery bypass graft and chronic total occlusion.
  
  
  CONCLUSIONS
  PCI patients with STEMI had the worst hospital and long-term prognosis. The mortality rate after hospital increased markedly in patients with NSTE-ACS. SESs seem to be more effective than PESs.
authors.affiliation: Department of Cardiology, The First Afﬁliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
authors.forename: Hai-Mu
authors.initials: HM
authors.lastname: Yao
authors.affiliation: Department of Integrated ICU, The First Afﬁliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
authors.forename: You-Dong
authors.initials: YD
authors.lastname: Wan
authors.affiliation: Department of Integrated ICU, The First Afﬁliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
authors.forename: Xiao-Juan
authors.initials: XJ
authors.lastname: Zhang
authors.affiliation: Department of Cardiology, The First Afﬁliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
authors.forename: De-Liang
authors.initials: DL
authors.lastname: Shen
authors.affiliation: Department of Cardiology, The First Afﬁliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
authors.forename: Jin-Ying
authors.initials: JY
authors.lastname: Zhang
authors.affiliation: Department of Cardiology, The First Afﬁliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
authors.forename: Ling
authors.initials: L
authors.lastname: Li
authors.affiliation: Department of Cardiology, The First Afﬁliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
authors.forename: Luo-Sha
authors.initials: LS
authors.lastname: Zhao
authors.affiliation: Department of Integrated ICU, The First Afﬁliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
authors.forename: Tong-Wen
authors.initials: TW
authors.lastname: Sun
mesh_terms: D002681:China; D015331:Cohort Studies; D003324:Coronary Artery Disease / Q000601:surgery*; D054855:Drug-Eluting Stents / Q000706:statistics & numerical data*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000706:statistics & numerical data*; D013995:Time; D016896:Treatment Outcome
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