title: Recruitment of plasmacytoid dendritic cells to skin regulates treatment responsiveness of actinic keratosis to imiquimod.
authors.affiliation: Departments of Dermatology, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.
authors.forename: Youichi
authors.initials: Y
authors.lastname: Ogawa
authors.affiliation: Departments of Dermatology, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan. Electronic address: tkawa@yamanashi.ac.jp.
authors.forename: Tatsuyoshi
authors.initials: T
authors.lastname: Kawamura
authors.affiliation: Departments of Dermatology, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Matsuzawa
authors.affiliation: Departments of Dermatology, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.
authors.forename: Rui
authors.initials: R
authors.lastname: Aoki
authors.affiliation: Departments of Dermatology, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.
authors.forename: Shinji
authors.initials: S
authors.lastname: Shimada
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage; D000634:Aminoquinolines / Q000008:administration & dosage*; D001706:Biopsy; D016207:Cytokines / Q000378:metabolism; D003713:Dendritic Cells / Q000166:cytology* / Q000187:drug effects; D006801:Humans; D000077271:Imiquimod; D007249:Inflammation; D016898:Interferon-alpha / Q000378:metabolism; D055623:Keratosis, Actinic / Q000188:drug therapy* / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism; D012867:Skin / Q000187:drug effects / Q000378:metabolism*; D051199:Toll-Like Receptor 7 / Q000378:metabolism; D014945:Wound Healing
chemical_list: D000276:Adjuvants, Immunologic; D000634:Aminoquinolines; D016207:Cytokines; D016898:Interferon-alpha; D012333:RNA, Messenger; C495348:TLR7 protein, human; D051199:Toll-Like Receptor 7; D000077271:Imiquimod
keywords: Actinic keratosis; IFN-α; Imiquimod; Plasmacytoid dendritic cells; TLR7