title: Hormone-sensitive lipase deficiency in humans.
abstract: The breakdown of cellular fat stores fuels energy production and multiple anabolic processes. Albert et al. (2014) demonstrate that the lack of hormone-sensitive lipase, a member of the enzyme trio that catabolizes fat, has pronounced effects on lipid metabolism, glucose homeostasis, and cell signaling in humans.
authors.affiliation: Institute of Molecular Biosciences, University of Graz, 8010 Graz, Austria. Electronic address: rudolf.zechner@uni-graz.at.
authors.forename: Rudolf
authors.initials: R
authors.lastname: Zechner
authors.affiliation: Inserm, UMR1048, Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases, 31432 Toulouse, France; University of Toulouse, Paul Sabatier University, 31062 Toulouse, France; Toulouse University Hospitals, Department of Clinical Biochemistry, 31059 Toulouse, France.
authors.forename: Dominique
authors.initials: D
authors.lastname: Langin
mesh_terms: D003924:Diabetes Mellitus, Type 2 / Q000235:genetics*; D005260:Female; D016368:Frameshift Mutation; D020022:Genetic Predisposition to Disease; D006801:Humans; D008066:Lipolysis / Q000235:genetics*; D008297:Male; D002787:Sterol Esterase / Q000235:genetics*
chemical_list: D002787:Sterol Esterase