title: Revisiting dimerization of acetoacetamide leading to 4,6-dimethyl-2-pyridone-5-carboxamide.
abstract: A commercially purchased acetoacetamide was found to dimerize during storage for several months to afford 4,6-dimethyl-2-pyridone-5-carboxamide. We successfully achieved the quantitative dimerization of acetoacetamide by using an acid catalyst. It was also found that the pyridone formed served as a self-catalyst of the dimerization.
authors.affiliation: School of Environmental Science and Engineering, Kochi University of Technology.
authors.forename: Sho
authors.initials: S
authors.lastname: Hirai
authors.forename: Haruyasu
authors.initials: H
authors.lastname: Asahara
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Sugimoto
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Saigo
authors.forename: Nagatoshi
authors.initials: N
authors.lastname: Nishiwaki
mesh_terms: D000081:Acetamides / Q000737:chemistry*; D002384:Catalysis; D009536:Niacinamide / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D058105:Polymerization; D011728:Pyridones / Q000138:chemical synthesis* / Q000737:chemistry*; D013997:Time Factors
chemical_list: D000081:Acetamides; D011728:Pyridones; D009536:Niacinamide; C030686:acetamide