title: Synthesis of functionalized β-lactams and pyrrolidine-2,5-diones through a metal-free sequential Ugi-4CR/cyclization reaction.
abstract: An efficient approach for the synthesis of functionalized β-lactams and pyrrolidine-2,5-diones was achieved through a sequential Ugi-4CR/cyclization reaction. Diversity-oriented synthesis, good to high yields, easy workup, and short reaction times are advantages of this procedure.
authors.affiliation: Peptide Chemistry Research Center, K. N. Toosi University of Technology , P.O. Box 15875-4416, Tehran, Iran.
authors.forename: Elmira
authors.initials: E
authors.lastname: Ghabraie
authors.forename: Saeed
authors.initials: S
authors.lastname: Balalaie
authors.forename: Saber
authors.initials: S
authors.lastname: Mehrparvar
authors.forename: Frank
authors.initials: F
authors.lastname: Rominger
mesh_terms: D020650:Combinatorial Chemistry Techniques / Q000379:methods; D003500:Cyclization; D008670:Metals / Q000737:chemistry*; D011760:Pyrrolidinones / Q000138:chemical synthesis*; D013237:Stereoisomerism; D047090:beta-Lactams / Q000138:chemical synthesis*
chemical_list: D008670:Metals; D011760:Pyrrolidinones; D047090:beta-Lactams