title: Meta analysis of efficacy and safety between Mammotome vacuum-assisted breast biopsy and open excision for benign breast tumor.
abstract: OBJECTIVE
  To compare the efficacy and safety between Mammotome vacuum-assisted breast biopsy (Mammotome VABB) and conventional open excision for benign breast tumor.
  
  
  METHODS
  A computer-based online search of Medline, PubMed, Embase, Ovid, Cochrane Library, VIP, Wanfang, CNKI and Chinese Biological Medicine Database was performed, and conference references were manually searched. With the Cochrane Collaboration Guidelines, all randomized controlled trials comparing mammotome minimally invasive operation and conventional open excision were systematically reviewed. The Cochrane Collaboration's RevMan 5.0 software was used for data analysis.
  
  
  RESULTS
  A total of 15 studies involving 5,256 patients was included. Meta-analyses showed no significant difference in the size of tumor, postoperative hematomas, ecchymosis, ecchymoma and residual disease between Mammotome VABB and conventional open excision. Mammotome VABB was superior to open excision as to the size of incision, intraoperative blood loss, operative time, healing time, size of scar, wound infection and breast deformation.
  
  
  CONCLUSIONS
  Mammotome VABB is an ideal method for benign breast tumor.
authors.affiliation: Department of General Surgery, Third Xiangya Hospital, Central South University, Changsha 410013, China.
authors.forename: Boni
authors.initials: B
authors.lastname: Ding
authors.affiliation: Department of General Surgery, Third Xiangya Hospital, Central South University, Changsha 410013, China.
authors.forename: Daojin
authors.initials: D
authors.lastname: Chen
authors.affiliation: Department of General Surgery, Third Xiangya Hospital, Central South University, Changsha 410013, China.
authors.forename: Xiaorong
authors.initials: X
authors.lastname: Li
authors.affiliation: Department of General Surgery, Third Xiangya Hospital, Central South University, Changsha 410013, China.
authors.forename: Hongyan
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Department of General Surgery, Third Xiangya Hospital, Central South University, Changsha 410013, China.
authors.forename: Yujun
authors.initials: Y
authors.lastname: Zhao
keywords: Mammotome vacuum-assisted breast biopsy (Mammotome VABB); Meta analysis; benign tumor; breast; surgery
references.citation: Arch Surg. 2003 Jul;138(7):796-800
references.pmid: 12860764
references.citation: Am J Surg. 2001 Oct;182(4):335-40
references.pmid: 11720666
references.citation: J Surg Oncol. 2009 Dec 15;100(8):675-80
references.pmid: 19731243
references.citation: Ann Surg. 2003 Nov;238(5):738-42
references.pmid: 14578737
references.citation: Tumori. 2005 Jul-Aug;91(4):351-4
references.pmid: 16277103
references.citation: J Radiol. 2005 Sep;86(9 Pt 1):1003-15
references.pmid: 16224340
references.citation: Surgery. 2002 May;131(5):497-501
references.pmid: 12019401
references.citation: Breast Cancer Res Treat. 2007 Mar;102(1):103-10
references.pmid: 16838109
references.citation: Am J Surg. 2002 Oct;184(4):332-6
references.pmid: 12383895