title: LTX-315 (Oncopore™): A short synthetic anticancer peptide and novel immunotherapeutic agent.
abstract: Several cationic antimicrobial peptides demonstrate promising anticancer effects. We have recently described the anticancer properties of LTX-315, a novel synthetic anticancer peptide, against syngeneic B16 melanomas. LTX-315 induced a complete regression of B16 melanomas and systemic protective immune responses following intralesional administration of the peptide.
authors.affiliation: Lytix Biopharma AS; Tromsø, Norway ; Department of Medical Biology; Faculty of Health Sciences; University of Tromsø; Tromsø, Norway.
authors.forename: Ketil André
authors.initials: KA
authors.lastname: Camilio
authors.affiliation: Lytix Biopharma AS; Tromsø, Norway.
authors.forename: Oystein
authors.initials: O
authors.lastname: Rekdal
authors.affiliation: Lytix Biopharma AS; Tromsø, Norway ; Department of Medical Biology; Faculty of Health Sciences; University of Tromsø; Tromsø, Norway.
authors.forename: Baldur
authors.initials: B
authors.lastname: Sveinbjörnsson
keywords: B16 melanoma; DAMPs; anticancer peptides; immunogenic cell death; inflammation; intralesional treatment
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