title: A novel treatment in X-linked agammaglobulinaemia - hyperbaric oxygen therapy in refractory chronic wounds.
abstract: Chronic wounds are a rare complication of X-linked agammaglobulinaemia (XLA). Fastidious organisms such as helicobacter bills have been reported in XLA with chronic wounds but sterile chronic wounds also occur. Hyperbaric Oxygen Therapy has been used in chronic wounds but has not previously been reported in primary antibody deficiencies. We present a case of a chronic wound in a patient with XLA refractory to antimicrobial therapy that made a remarkable recovery following Hyperbaric Oxygen Therapy.
authors.affiliation: The Belfast HSC Trust, Belfast, UK, cathal.steele@belfasttrust.hscni.net.
authors.forename: C L
authors.initials: CL
authors.lastname: Steele
authors.forename: C
authors.initials: C
authors.lastname: Cridge
authors.forename: J D M
authors.initials: JD
authors.lastname: Edgar
mesh_terms: D000328:Adult; D000361:Agammaglobulinemia / Q000150:complications / Q000276:immunology / Q000628:therapy*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002908:Chronic Disease; D004351:Drug Resistance; D004848:Epithelium / Q000187:drug effects* / Q000473:pathology; D040181:Genetic Diseases, X-Linked / Q000150:complications / Q000276:immunology / Q000628:therapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D007223:Infant; D018836:Inflammation Mediators / Q000378:metabolism; D007869:Leg Injuries / Q000150:complications / Q000276:immunology / Q000628:therapy*; D020127:Recovery of Function; D012008:Recurrence; D014946:Wound Infection / Q000209:etiology / Q000276:immunology / Q000628:therapy*
chemical_list: D000900:Anti-Bacterial Agents; D018836:Inflammation Mediators
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