title: Effect of Moderate Aerobic Training on Bone Metabolism Indices among Adult Humans.
abstract: OBJECTIVE
  This study assessed the osteogenic effect (T-Score) and changes in bone markers in healthy subjects by 12-weeks of aerobic training.
  
  
  METHODS
  Total 65 healthy subjects (36 males, 29 females), their age ranged between 30 and 60 years with normal body mass index, were recruited to participate in this study and they were selected among healthy subjects who do not have any metabolic disorders and were not receiving any medication that could affect the bone turnover. Standardized physical examination and collection of serum samples were performed at base line and after 12 weeks of moderate aerobic training to measure bone formation markers (osteocalcin (OC) and bone specific alkaline Phosphatase (BAP) and bone resorption marker Deoxypyridinoline (DPD), and serum calcium. Each subject participated in exercise training program for 12 weeks, three times per week.
  
  
  RESULTS
  The results showed that the 12 weeks of moderate aerobic training produced a significant improvement in all bone metabolism indices including Serum bone-specific alkaline phosphatase, serum osteocalcin, serum free Calcium and bone mineral density among all subjects. Conclusion : Moderate intensity of aerobic training exerts significant positive effects on bone formation marker and bone density associated with a significant decrease in the rate of bone resorption that could assist in preventing or decelerating osteoporosis.
authors.affiliation: Ahmad H. Alghadir, Department of Rehabilitation Sciences, College of Applied Medical Sciences, Rehabilitation Research Chair King Saud University, Riyadh, Kingdom of Saudi Arabia.
authors.forename: Ahmad H
authors.initials: AH
authors.lastname: Alghadir
authors.affiliation: Farag A. Aly, Faculty of Physical Therapy, Cairo University, Cairo, Egypt. Rehabilitation Research Chair King Saud University, Riyadh, Kingdom of Saudi Arabia.
authors.forename: Farag A
authors.initials: FA
authors.lastname: Aly
authors.affiliation: Sami A. Gabr, Department of Anatomy, Faculty of Medicine, Mansoura University, Rehabilitation Research Chair King Saud University, Riyadh, Kingdom of Saudi Arabia. Egypt.
authors.forename: Sami A
authors.initials: SA
authors.lastname: Gabr
keywords: Aerobic exercise; Bone formation marker; Calcium; S-BAP; S-DPD; Serum Osteocalcin
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