title: Comparison of micronutrient levels in children with cerebral palsy and neurologically normal controls.
abstract: OBJECTIVE
  To measure levels of micronutrients in children with cerebral palsy and compare them with neurologically normal children of similar nutritional status.
  
  
  METHODS
  Fifty children with cerebral palsy (2-12 y) and 50 age and sex matched controls of similar nutritional status were enrolled. Detailed dietary history was recorded and nutritional status assessed. Venous blood (3 ml) was drawn for analysis. Micronutrient levels were measured as per standard technique.
  
  
  RESULTS
  Serum iron was 12.6 ± 5.9 and 20.9 ± 3.3 μmol/L in CP and controls respectively (P < 0.001). Mean copper levels were 106.2 ± 38.3 μg/dl in CP and 128.8 ± 20.2 μg/dl in controls (P < 0.001); magnesium levels were 1.97 ± 0.4 and 2.2 ± 0.3 mg/dl (P = 0.003). Zinc levels were similar in CP and controls (P = 0.979). The mean energy intake was significantly less in CP (P = 0.016). Mean protein intake did not vary significantly (P = 0.847). No correlation was found between energy intake and serum levels of micronutrients (P > 0.05). There was no difference in micronutrient levels with respect to gross motor functional classification system (GMFCS) grades and limb involvement (P > 0.05).
  
  
  CONCLUSIONS
  The serum levels of iron, copper and magnesium are significantly less in children with cerebral palsy, hence the need for supplementation.
authors.affiliation: Department of Pediatrics, University College of Medical Sciences and Guru Tegh Bahadur Hospital, Dilshad Garden, New Delhi, India.
authors.forename: Swati
authors.initials: S
authors.lastname: Kalra
authors.forename: Anju
authors.initials: A
authors.lastname: Aggarwal
authors.forename: Neelam
authors.initials: N
authors.lastname: Chillar
authors.forename: M M A
authors.initials: MM
authors.lastname: Faridi
mesh_terms: D000886:Anthropometry / Q000379:methods; D002547:Cerebral Palsy / Q000097:blood / Q000175:diagnosis; D002648:Child; D002675:Child, Preschool; D003300:Copper / Q000097:blood*; D019587:Dietary Supplements; D002149:Energy Intake; D005260:Female; D006801:Humans; D007194:India; D007501:Iron / Q000097:blood*; D008274:Magnesium / Q000097:blood*; D008297:Male; D018977:Micronutrients / Q000097:blood; D015596:Nutrition Assessment; D009752:Nutritional Status
chemical_list: D018977:Micronutrients; D003300:Copper; D007501:Iron; D008274:Magnesium
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