title: Vaccination recommendations and risk of meningitis following cochlear implantation.
abstract: OBJECTIVE
  The Centers for Disease Control and Prevention has established vaccination guidelines for cochlear implant recipients to address the concern for implant-associated bacterial meningitis. Since their inception in 2002, these guidelines have undergone several revisions. We review the rationale and development of the current vaccination schedule.
  
  
  RESULTS
  Bacterial meningitis is a rare yet potentially life-threatening complication of cochlear implantation. The recommendations for pneumococcal vaccination have evolved to a state in which nearly all cochlear implant patients receive a combination of both the PCV7 or PCV13 and PPSV23.
  
  
  CONCLUSIONS
  Streptococcus pneumoniae vaccinations have dramatically decreased the incidence of serotype-specific invasive pneumococcal disease across all age groups. However, the optimal timing of immunization remains unclear in cochlear implant candidates.
authors.affiliation: The Otology Group of Vanderbilt, Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
authors.forename: Charissa N
authors.initials: CN
authors.lastname: Kahue
authors.forename: Alex D
authors.initials: AD
authors.lastname: Sweeney
authors.forename: Matthew L
authors.initials: ML
authors.lastname: Carlson
authors.forename: David S
authors.initials: DS
authors.lastname: Haynes
mesh_terms: D000208:Acute Disease; D019929:Cochlear Implantation / Q000009:adverse effects*; D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D006801:Humans; D007115:Immunization Schedule; D008586:Meningitis, Pneumococcal / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control*; D010033:Otitis Media / Q000150:complications; D022242:Pneumococcal Vaccines / Q000627:therapeutic use*; D012307:Risk Factors; D014611:Vaccination / Q000592:standards*; D018074:Vaccines, Conjugate / Q000627:therapeutic use
chemical_list: D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D022242:Pneumococcal Vaccines; D018074:Vaccines, Conjugate