title: A series of 4 cases of distinct keratopathy secondary to dysproteinemia: immunotactoid keratopathy.
abstract: OBJECTIVE
  To describe a series of 4 cases of immunotactoid keratopathy (ITK) secondary to monoclonal gammopathy.
  
  
  METHODS
  Multicentre retrospective case series of 4 patients.
  
  
  METHODS
  Eight eyes of 4 patients presenting to a cornea service with ITK.
  
  
  METHODS
  Retrospective case series of 4 patients referred between 2011 and 2013 for bilateral corneal opacities. Work-up including serum protein electrophoresis was performed, and slit-lamp photographs were obtained.
  
  
  RESULTS
  After investigation, diagnoses of ITK secondary to monoclonal gammopathy of unknown significance were established in 3 cases. In 1 patient, the diagnosis of monoclonal gammopathy of unknown significance was established prereferral.
  
  
  CONCLUSIONS
  ITK secondary to plasma cell disorders can clinically resemble a broad category of disease processes and must be considered when evaluating patients with bilateral peripheral stromal opacities. Our series validates previously proposed classification schemes for these opacities.
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver General Hospital, Vancouver, B.C.. Electronic address: hall.riley@usask.ca.
authors.forename: Riley B
authors.initials: RB
authors.lastname: Hall
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver General Hospital, Vancouver, B.C.
authors.forename: Sonia N
authors.initials: SN
authors.lastname: Yeung
authors.affiliation: Division of Hematology, Department of Medicine, Vancouver General Hospital, Vancouver, B.C.
authors.forename: Paul R
authors.initials: PR
authors.lastname: Yenson
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver General Hospital, Vancouver, B.C.; Discipline of Ophthalmology, University of Sydney, Sydney Eye Hospital Campus, Macquarie Street, Sydney, New South Wales, Australia.
authors.forename: Gregory
authors.initials: G
authors.lastname: Moloney
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001798:Blood Proteins / Q000032:analysis; D003318:Corneal Opacity / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007145:Immunoglobulin kappa-Chains / Q000097:blood; D008297:Male; D008875:Middle Aged; D010265:Paraproteinemias / Q000150:complications* / Q000175:diagnosis; D012189:Retrospective Studies; D014786:Vision Disorders / Q000209:etiology; D014792:Visual Acuity
chemical_list: D001798:Blood Proteins; D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains