title: Influence of placental cord drainage in management of the third stage of labor: a multicenter randomized controlled study.
abstract: OBJECTIVE
  The aim of this study is to assess the effect of placental drainage during active management of the third stage of labor on reducing both blood loss and the length of the third stage.
  
  
  METHODS
  This prospective randomized controlled trial included 485 patients who underwent vaginal delivery in two tertiary hospital. Subjects were randomly allocated to the cord drainage group, in which the cord was unclamped after cutting (n = 242), or the control group, in which the cord was left clamped (n = 243). The primary outcome was mean blood loss during the third and fourth stages of labor.
  
  
  RESULTS
  The mean estimated blood loss was significantly lower in the cord drainage group than in the control group (207.04 ± 123.3 vs. 277.63 ± 246.9 mL, respectively; p ˂ 0.001). The third stage of labor was significantly shorter in the cord drainage group than in the control group (3.5 ± 1.9 vs. 7.7 ± 3.4 minutes, respectively; p ˂ 0.001). No adverse events occurred during the cord drainage period.
  
  
  CONCLUSIONS
  Active management of the third stage of labor with the cord drainage method significantly reduced postpartum blood loss and the duration of the third stage.
authors.affiliation: Department of Obstetrics and Gynecology, Şişli Etfal Education and Research Hospital, Istanbul, Turkey.
authors.forename: Osman
authors.initials: O
authors.lastname: Asicioglu
authors.affiliation: Department of Obstetrics and Gynecology, Şişli Etfal Education and Research Hospital, Istanbul, Turkey.
authors.forename: Canan
authors.initials: C
authors.lastname: Unal
authors.affiliation: Department of Obstetrics and Gynecology, Kanuni Sultan Suleyman Education and Research Hospital, Istanbul, Turkey.
authors.forename: Berhan Besimoglu
authors.initials: BB
authors.lastname: Asicioglu
authors.affiliation: Department of Obstetrics and Gynecology, Şişli Etfal Education and Research Hospital, Istanbul, Turkey.
authors.forename: Osman
authors.initials: O
authors.lastname: Temizkan
authors.affiliation: Department of Obstetrics and Gynecology, Kanuni Sultan Suleyman Education and Research Hospital, Istanbul, Turkey.
authors.forename: Gokhan
authors.initials: G
authors.lastname: Yildirım
authors.affiliation: Department of Obstetrics and Gynecology, Şişli Etfal Education and Research Hospital, Istanbul, Turkey.
authors.forename: Bulent
authors.initials: B
authors.lastname: Arici
authors.affiliation: Department of Obstetrics and Gynecology, Şişli Etfal Education and Research Hospital, Istanbul, Turkey.
authors.forename: Sibel
authors.initials: S
authors.lastname: Gulova
mesh_terms: D000328:Adult; D036861:Delivery, Obstetric / Q000379:methods*; D004322:Drainage / Q000379:methods*; D005260:Female; D006801:Humans; D007749:Labor Stage, Third; D006473:Postpartum Hemorrhage / Q000517:prevention & control / Q000601:surgery*; D011247:Pregnancy; D011446:Prospective Studies; D062606:Tertiary Care Centers; D014421:Turkey; D014470:Umbilical Cord / Q000601:surgery*; D055815:Young Adult