title: Identification of 3-chloro-1,2-propandiol using molecularly imprinted composite solid-phase extraction materials.
abstract: A novel molecularly imprinted material based on silica microparticles was synthesized by surface polymerization with 3-chloro-1,2-propandiol (3-MCPD) as a template molecule. The molecularly imprinted polymer (MIP) was characterized by infrared spectroscopy and scanning electron microscopy. The adsorption of 3-MCPD by MIP was measured by gas chromatography with electron capture detection (GC-ECD) and an equilibrium binding experiment. Scatchard analysis revealed that the maximum apparent binding capacities of the MIP and non-imprinted polymer (NIP) were 67.64 and 23.31 μmol/g, respectively. The new adsorbent was successfully used in solid-phase extraction (SPE) to selectively enrich and determine 3-MCPD in soy sauce samples. The MIP-SPE column achieves recoveries higher than 92.7% with a relative standard deviation of less than 1.83%. The MIP-SPE-GC protocol improved the selectivity and eliminated the effects of template leakage on quantitative analysis and could be used for the determination of 3-MCPD in other complex food samples.
authors.affiliation: Key Laboratory of Agro-food Safety and Quality of Ministry of Agriculture, Institute of Quality Standards and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, No. 12, Zhongguancun South Street, Beijing, 100081, People's Republic of China, GZ-liyun@126.com.
authors.forename: Yun
authors.initials: Y
authors.lastname: Li
authors.forename: Chuangmu
authors.initials: C
authors.lastname: Zheng
authors.forename: Xiulan
authors.initials: X
authors.lastname: Sun
authors.forename: Ben
authors.initials: B
authors.lastname: Ouyang
authors.forename: Ping
authors.initials: P
authors.lastname: Ni
authors.forename: Yingzhi
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000327:Adsorption; D054802:Molecular Imprinting; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D011409:Propylene Glycols / Q000737:chemistry / Q000302:isolation & purification*; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*
chemical_list: D011108:Polymers; D011409:Propylene Glycols