title: Polychlorinated biphenyls and selected organochlorine pesticides in serum of Slovak population from industrial and non-industrial areas.
abstract: The concentrations of indicator polychlorinated biphenyls (PCBs No. 28, 52, 101, 138, 153 and 180) and organochlorine pesticides (HCB, p,p'-DDE and p,p'-DDT) in 121 blood serum specimens collected from non-occupationally exposed adults living in contaminated and comparison areas were determined using high-resolution gas chromatography/electron capture detection (HRGC/ECD). The sum of the serum concentrations of the three most abundant PCB congeners (No. 138, 153 and 180) found in participants (N = 81) living in industrial areas near incinerators, metallurgical and chemical plants (Krompachy, Kosice, Nemecka and Sala) was significantly higher (p < 0.001) than in participants living in villages and towns without known sources causing persistent organic pollutant (POP) contamination (N = 40). Similarly, significant differences were observed for p,p'-DDE (p < 0.0001) and p,p'-DDT (p < 0.002). However, a Mann-Whitney U test between groups showed that the difference for HCB was not statistically significant (p = 0.089). Age was positively correlated with the sum of PCBs (No. 138, 153 and 180), HCB and the sum of p,p'-DDE and p,p'-DDT (p < 0.01 for all).
authors.affiliation: Department of Toxic Organic Pollutants, Slovak Medical University, Limbová 12, 833 03, Bratislava, Slovak Republic, jana.chovancova@szu.sk.
authors.forename: Jana
authors.initials: J
authors.lastname: Chovancová
authors.forename: Beáta
authors.initials: B
authors.lastname: Drobná
authors.forename: Anna
authors.initials: A
authors.lastname: Fabišiková
authors.forename: Kamil
authors.initials: K
authors.lastname: Conka
authors.forename: Soňa
authors.initials: S
authors.lastname: Wimmerová
authors.forename: Marian
authors.initials: M
authors.lastname: Pavuk
mesh_terms: D000328:Adult; D000368:Aged; D003634:DDT / Q000097:blood; D003633:Dichlorodiphenyl Dichloroethylene / Q000097:blood; D004781:Environmental Exposure / Q000706:statistics & numerical data*; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000097:blood*; D005260:Female; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000097:blood*; D007221:Industry; D008297:Male; D008875:Middle Aged; D010575:Pesticides / Q000097:blood*; D011078:Polychlorinated Biphenyls / Q000097:blood*; D018154:Slovakia; D055815:Young Adult
chemical_list: D004785:Environmental Pollutants; D006843:Hydrocarbons, Chlorinated; D010575:Pesticides; D003633:Dichlorodiphenyl Dichloroethylene; D003634:DDT; D011078:Polychlorinated Biphenyls
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