title: Ventilation catheter-assisted airway stenting under local anaesthesia for patients with airway stenosis: initial clinical experience.
abstract: OBJECTIVE
  This report details our preliminary results of ventilation catheter-assisted airway stenting under local anaesthesia for airway stenosis.
  
  
  METHODS
  Fifteen consecutive patients with airway stenosis underwent ventilation catheter-assisted airway stenting under local anaesthesia. A 4F angiographic catheter was used as the ventilation catheter. During the treatment, the distal tip of the ventilation catheter was placed across the stenosis into one of the main bronchi and the proximal tip of the catheter was linked to the oxygen tube for oxygen supplementation. Airway stenting was performed under ventilation support. Patients maintained autonomous respiration throughout the procedures. Data on technical success, clinical outcome and follow-up were collected and analysed.
  
  
  RESULTS
  Ventilation catheter-assisted airway stenting under local anaesthesia was technically successful and well tolerated in all patients. Respiratory difficulty was improved in all patients after treatment. The average Hugh-Jones classification grade, arterial oxygen saturation value, and respiratory rate improved from 4.20 ± 0.68, 80.60 ± 3.83%, and 30.33 ± 2.02 times/min, respectively, before stenting to 1.47 ± 0.52 (P < 0.001), 94.93 ± 1.33% (P < 0.001), and 18.07 ± 1.33 times/min (P < 0.001), respectively, after stenting. After 2-11 months (average 5.73 ± 2.40 months) of follow-up, one patient experienced re-stenosis of the stent. The mean survival time of the 15 patients was 162.00 ± 71.60 days (range 55-320 days).
  
  
  CONCLUSIONS
  Ventilation catheter-assisted airway stenting under local anaesthesia can be an effective, simple and safe method for airway stenosis.
authors.affiliation: Department of Interventional Radiology, The Affiliated Hospital of Xuzhou Medical College, 99 West Huai-hai Road, Xuzhou, 221006, Jiangsu, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Wei
authors.forename: Yu-Fei
authors.initials: YF
authors.lastname: Fu
authors.forename: Ke
authors.initials: K
authors.lastname: Zhang
authors.forename: Hao-Guang
authors.initials: HG
authors.lastname: Wan
authors.forename: Hao
authors.initials: H
authors.lastname: Xu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000402:Airway Obstruction / Q000000981:diagnostic imaging / Q000628:therapy*; D000772:Anesthesia, Local; D001982:Bronchial Diseases / Q000628:therapy*; D057785:Catheters; D003251:Constriction, Pathologic / Q000628:therapy; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D012121:Respiration, Artificial / Q000295:instrumentation*; D015607:Stents; D014057:Tomography, X-Ray Computed; D014135:Tracheal Stenosis / Q000628:therapy*; D016896:Treatment Outcome
references.citation: Anesth Analg. 2000 Jun;90(6):1436-40
references.pmid: 10825336
references.citation: Arch Bronconeumol. 2012 Feb;48(2):43-8
references.pmid: 22137422
references.citation: Thorax. 1987 Sep;42(9):656-60
references.pmid: 3686456
references.citation: Clin Radiol. 2013 Apr;68(4):358-64
references.pmid: 23137611
references.citation: Ann Thorac Surg. 1982 Nov;34(5):564-71
references.pmid: 6753772
references.citation: Cardiovasc Intervent Radiol. 2007 Jan-Feb;30(1):74-8
references.pmid: 17031728
references.citation: Am J Hosp Palliat Care. 2013 Nov;30(7):683-9
references.pmid: 23070620
references.citation: J Vasc Interv Radiol. 2001 Jan;12(1):55-9
references.pmid: 11200354
references.citation: Minim Invasive Ther Allied Technol. 2012 Mar;21(2):108-12
references.pmid: 21417832
references.citation: Anesth Analg. 1999 Feb;88(2):298-301
references.pmid: 9972744
references.citation: Cardiovasc Intervent Radiol. 1996 Mar-Apr;19(2):91-6
references.pmid: 8662165