title: MDSCs: the final frontier of the microenvironment in CLL?
abstract: In this issue of Blood, Jitschin et al identify increased numbers of myeloid-derived suppressor cells (MDSCs) in untreated patients with chronic lymphocytic leukemia (CLL) suppressing T cells and inducing regulatory T cells (T(regs)), resulting in impaired immune responses.
authors.affiliation: UNIVERSITY MEDICAL CENTER FREIBURG.
authors.forename: Katja
authors.identifier: http://orcid.org/0000-0001-6588-3076
authors.initials: K
authors.lastname: Zirlik
mesh_terms: D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000276:immunology*; D008213:Lymphocyte Activation; D008297:Male; D022423:Myeloid Cells / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*
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