title: Corneal allograft reaction associated with nonocular inflammation.
abstract: Corneal allograft rejection is known to have many risk factors, including ocular infection and inflammation. Although not reported in the literature, local nonocular inflammation may also have the ability to incite a graft reaction. We report 2 cases, one with dental inflammation and the other with a facial abscess, with simultaneous corneal transplant rejection. Possible pathophysiology and a review of the literature are given.
authors.affiliation: Cornea and Refractive Surgery Service, Massachusetts Eye and Ear Infirmary.
authors.forename: Gargi Khare
authors.initials: GK
authors.lastname: Vora
authors.affiliation: Cornea and Refractive Surgery Service, Massachusetts Eye and Ear Infirmary.
authors.forename: Joseph B
authors.initials: JB
authors.lastname: Ciolino
mesh_terms: D000208:Acute Disease; D016039:Corneal Transplantation; D005260:Female; D005491:Focal Infection, Dental / Q000150:complications*; D006084:Graft Rejection / Q000209:etiology*; D006801:Humans; D007249:Inflammation / Q000150:complications; D008297:Male; D008875:Middle Aged; D013207:Staphylococcal Skin Infections / Q000150:complications*
references.citation: Cornea. 2011 Dec;30(12):1328-35
references.pmid: 21926910
references.citation: Am J Ophthalmol. 1989 Jun 15;107(6):647-54
references.pmid: 2658619
references.citation: Trans Am Ophthalmol Soc. 1983;81:361-402
references.pmid: 6375088
references.citation: Am J Ophthalmol. 1948 Nov;31(11):1375-83
references.pmid: 18894706
references.citation: Cornea. 2011 Oct;30(10):1088-97
references.pmid: 21795976
references.citation: Cornea. 2012 Oct;31(10):1141-7
references.pmid: 22488114
references.citation: Am J Ophthalmol. 2011 Sep;152(3):358-363.e2
references.pmid: 21683335