title: Could the human papillomavirus vaccination be cost-effective in males for the prevention of oropharyngeal cancer?
abstract: Could the human papillomavirus (HPV) vaccination be cost-effective in males for the prevention of oropharyngeal squamous cell cancer (OPC)? It could be under certain conditions. Research on HPV vaccine has focused mainly on females. However, within the next decade, it is predicted that OPC will surpass cervical cancer as the most common HPV-related cancer, and it is postulated that HPV vaccination may alter the incidence of OPC. The purpose of this editorial is to comment on the potential cost-effectiveness of HPV vaccination in males for OPC prevention by addressing three elements payers often consider when making a decision to fund an intervention and to provide an overview of recent findings regarding the cost-effectiveness of HPV vaccine in males.
authors.affiliation: Centre for Excellence in Economic Analysis Research, St. Michael's Hospital, 30 Bond Street, Toronto, Ontario, M5B 1W8, Canada.
authors.forename: Wanrudee
authors.initials: W
authors.lastname: Isaranuwatchai
authors.forename: Donna M
authors.initials: DM
authors.lastname: Graham
authors.forename: Lillian L
authors.initials: LL
authors.lastname: Siu
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Hoch
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000191:economics* / Q000453:epidemiology / Q000517:prevention & control* / Q000821:virology; D003362:Cost-Benefit Analysis; D016527:Drug Costs; D006258:Head and Neck Neoplasms / Q000191:economics* / Q000453:epidemiology / Q000517:prevention & control* / Q000821:virology; D006801:Humans; D015994:Incidence; D008297:Male; D009959:Oropharyngeal Neoplasms / Q000191:economics* / Q000453:epidemiology / Q000517:prevention & control* / Q000821:virology; D030361:Papillomavirus Infections / Q000191:economics* / Q000453:epidemiology / Q000517:prevention & control* / Q000821:virology; D053918:Papillomavirus Vaccines / Q000191:economics* / Q000627:therapeutic use*; D012307:Risk Factors; D012737:Sex Factors; D000077195:Squamous Cell Carcinoma of Head and Neck; D016896:Treatment Outcome; D014611:Vaccination / Q000191:economics*
chemical_list: D053918:Papillomavirus Vaccines
keywords: cost–effectiveness analysis; economic evaluation; human papillomavirus; oropharyngeal cancer; vaccine