title: Balance of apoptotic cell death and survival in allergic diseases.
abstract: Allergic diseases result from over-reaction of the immune system in response to exogenous allergens, where inflammatory cells have constantly extended longevity and contribute to an on-going immune response in allergic tissues. Here, we review disequilibrium in the death and survival of epithelial cells and inflammatory cells in the pathological processes of asthma, atopic dermatitis, and other allergic diseases.
authors.affiliation: Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China; Key Site of National Clinical Research Center for Respiratory Disease, Hangzhou, Zhejiang 310058, China.
authors.forename: Bao-Ping
authors.initials: BP
authors.lastname: Tian
authors.affiliation: Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China; Key Site of National Clinical Research Center for Respiratory Disease, Hangzhou, Zhejiang 310058, China.
authors.forename: Hong-Bin
authors.initials: HB
authors.lastname: Zhou
authors.affiliation: Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China; Key Site of National Clinical Research Center for Respiratory Disease, Hangzhou, Zhejiang 310058, China.
authors.forename: Li-Xia
authors.initials: LX
authors.lastname: Xia
authors.affiliation: Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China; Key Site of National Clinical Research Center for Respiratory Disease, Hangzhou, Zhejiang 310058, China; State Key Laboratory of Respiratory Diseases, Guangzhou, Guangdong 510120, China. Electronic address: huahaoshen@zju.edu.cn.
authors.forename: Hua-Hao
authors.initials: HH
authors.lastname: Shen
authors.affiliation: Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China; Key Site of National Clinical Research Center for Respiratory Disease, Hangzhou, Zhejiang 310058, China; Department of Pharmacology, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China. Electronic address: yings@zju.edu.cn.
authors.forename: Songmin
authors.initials: S
authors.lastname: Ying
mesh_terms: D000485:Allergens / Q000276:immunology; D000818:Animals; D017209:Apoptosis; D002470:Cell Survival; D004195:Disease Models, Animal; D004847:Epithelial Cells / Q000166:cytology / Q000378:metabolism; D006098:Granulocytes / Q000166:cytology / Q000378:metabolism; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology* / Q000473:pathology; D008407:Mast Cells / Q000166:cytology / Q000378:metabolism; D009000:Monocytes / Q000166:cytology / Q000378:metabolism
chemical_list: D000485:Allergens
keywords: Allergic disease; Apoptosis; Cell death; Epithelial cells; Inflammatory cells