title: Effect of maternal body mass index on cord blood erthropoietin concentrations.
abstract: OBJECTIVE
  To examine the hypothesis that maternal body mass index (BMI) (an index of maternal adiposity) correlates with cord blood concentrations of erythropoietin (EPO).
  
  
  METHODS
  Cross-sectional cohort study of consecutively born singleton term healthy infants born to mothers with various BMIs. Excluded were infants with major factors known to be associated with a potential increase in fetal erythropoiesis. Prepregnancy maternal BMI was calculated from maternal recollection.
  
  
  RESULTS
  There was a significant correlation between EPO concentrations and maternal BMI (R = 0.427, P = 0.007). This correlation remained significant in multiple stepwise regression analysis using the EPO concentration as the dependent variable, and maternal age, parity, gestational age and Apgar scores (1 or 5 min) as potential confounders.
  
  
  CONCLUSIONS
  Cord blood concentrations of EPO correlate with maternal BMI. We speculate that increasing maternal BMI may represent a relative hypoxic burden on the fetus.
authors.affiliation: 1] Department of Obstetrics and Gynecology, The Lis Maternity Hospital, Tel Aviv-Sourasky Medical Center, Tel Aviv, Israel [2] The Sackler School of Medicine, Tel Aviv, Israel.
authors.forename: S
authors.initials: S
authors.lastname: Barak
authors.affiliation: 1] The Sackler School of Medicine, Tel Aviv, Israel [2] Department of Neonatology, The Lis Maternity Hospital, Tel Aviv-Sourasky Medial Center, Tel Aviv, Israel.
authors.forename: F B
authors.initials: FB
authors.lastname: Mimouni
authors.affiliation: Department of Hematology, The Lis Maternity Hospital, Tel Aviv-Sourasky Medial Center, Tel Aviv, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Stern
authors.affiliation: 1] The Sackler School of Medicine, Tel Aviv, Israel [2] Department of Neonatology, The Lis Maternity Hospital, Tel Aviv-Sourasky Medial Center, Tel Aviv, Israel.
authors.forename: N
authors.initials: N
authors.lastname: Cohen
authors.affiliation: 1] The Sackler School of Medicine, Tel Aviv, Israel [2] Department of Neonatology, The Lis Maternity Hospital, Tel Aviv-Sourasky Medial Center, Tel Aviv, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Marom
mesh_terms: D000328:Adult; D001034:Apgar Score; D015992:Body Mass Index; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D004921:Erythropoietin / Q000097:blood*; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D005865:Gestational Age; D006801:Humans; D008423:Maternal Age; D010298:Parity; D011247:Pregnancy
chemical_list: D004921:Erythropoietin
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