title: [Changes of fingerprints with crude and processed cassiae semen in xuezhiling tablets].
abstract: OBJECTIVE
  To establish an effective and convenient method for HPLC fingerprints of Xuezhiling tablets and new Xuezhiling tablets, and to observe the changes of fingerprint with crude and processed Cassiae Semen in Xuezhiling tablets.
  
  
  METHODS
  The HPLC with Agilent TC-C18 (4.6 mm x 250 mm, 5 microm) column was used for the gradient elution of acetonitrile-0.1% phosphoric acid solution, at the flow rate of 1.0 mL/min. Detection wavelength was set at 284 nm and the column temperature was 30 degrees C.
  
  
  RESULTS
  Ten batches of Xuezhiling tablets and new Xuezhiling tablets were tested and gained HPLC fingerprint containing 20 common peaks, respectively.
  
  
  CONCLUSIONS
  This method is stable and reliable. The number of common peaks of fingerprint had little change after the crude and processed Cassiae Semen in Xuezhiling tablets interchangeably, but the contents of some components had significant changes.
authors.forename: Yan-Chao
authors.initials: YC
authors.lastname: Zheng
authors.forename: Xian-Kuan
authors.initials: XK
authors.lastname: Li
authors.forename: Bao-Li
authors.initials: BL
authors.lastname: Mi
authors.forename: Zhen-Qiu
authors.initials: ZQ
authors.lastname: Zhang
mesh_terms: D034902:Alisma / Q000737:chemistry; D000880:Anthraquinones / Q000032:analysis*; D002366:Cassia / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification / Q000592:standards; D004642:Emodin / Q000032:analysis; D000960:Hypolipidemic Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000592:standards; D010946:Plants, Medicinal / Q000737:chemistry*; D011786:Quality Control
chemical_list: D000880:Anthraquinones; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D000960:Hypolipidemic Agents; D004642:Emodin