title: Effect of the timing of posthatch feed restrictions on the deposition of fat during broiler breast muscle development.
abstract: The effect of the timing of posthatch feed restriction on adipose deposition and adipogenic gene expression in the broiler pectoralis major muscle was studied by applying a 20% feed restriction either the first or second week after hatch. Broiler chicks at hatch were divided into a full-fed (control) group and a 20% feed restriction group. The expression of adipogenic genes, peroxisome proliferator-activated receptor gamma (PPARγ), and CCAAT/enhancer-binding protein alpha (C/EBPα) were measured. The expression of both PPARγ and C/EBPα was affected by the wk 1 feed restriction with expression significantly increased during the first week posthatch. The deposition of fat within the pectoralis major muscle was affected by the timing of the feed restriction. Extensive fat depots were present by 27 d of age in the pectoralis major muscle of the wk 1 restricted group compared with the control. Fat deposition was eliminated when the 20% feed restriction occurred in wk 2. Taken together, these results demonstrate that the timing of early posthatch feed restrictions in chicks is critical in the deposition of fat in the pectoralis major muscle and expression of adipogenic genes.
authors.affiliation: Department of Animal Sciences, Ohio Agricultural Research and Development Center, The Ohio State University, 1680 Madison Ave, Wooster 44691 Velleman.1@osu.edu.
authors.forename: S G
authors.initials: SG
authors.lastname: Velleman
authors.affiliation: Department of Animal Sciences, Ohio Agricultural Research and Development Center, The Ohio State University, 1680 Madison Ave, Wooster 44691.
authors.forename: C S
authors.initials: CS
authors.lastname: Coy
authors.affiliation: Aviagen Incorporated, 5015 Bradford Dr, Huntsville, AL 35805.
authors.forename: D A
authors.initials: DA
authors.lastname: Emmerson
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism*; D000822:Animal Husbandry; D000818:Animals; D030161:Avian Proteins / Q000235:genetics / Q000378:metabolism; D022763:CCAAT-Enhancer-Binding Protein-alpha / Q000235:genetics / Q000378:metabolism; D002645:Chickens / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D005508:Food Deprivation; D008297:Male; D024510:Muscle Development; D047495:PPAR gamma / Q000235:genetics / Q000378:metabolism; D010369:Pectoralis Muscles / Q000254:growth & development / Q000378:metabolism*; D060888:Real-Time Polymerase Chain Reaction / Q000662:veterinary
chemical_list: D030161:Avian Proteins; D022763:CCAAT-Enhancer-Binding Protein-alpha; D047495:PPAR gamma
keywords: adipogenic gene; chick; fat; feed restriction; muscle