title: Ab interno stenting procedures.
abstract: Trabecular bypass was first used as a surgical treatment for glaucoma more than 100 years ago and aims to circumvent the trabecular meshwork, thought to be the main site of aqueous humor outflow resistance. The emerging field of microinvasive glaucoma surgery has brought a new ab interno trabecular microbypass stent through the U.S. Food and Drug Administration-approval process, and data from long-term randomized prospective trials have shown the safety and intraocular pressure-lowering value of trabecular microbypass. This review discusses the historical evolution of trabecular microbypass and describes new and forthcoming surgical options along with available clinical safety and efficacy data.
  
  
  BACKGROUND
  Proprietary or commercial disclosures are listed after the references.
authors.affiliation: From the Atlanta Ophthalmology Associates (Brown), Atlanta Veterans Medical Center, and Emory University Eye Center (Lynch), Atlanta, Georgia, and the Department of Ophthalmology (Radcliffe), Weill Cornell Medical College, New York, New York, USA. Electronic address: drradcliffe@gmail.com.
authors.forename: Nathan M
authors.initials: NM
authors.lastname: Radcliffe
authors.affiliation: From the Atlanta Ophthalmology Associates (Brown), Atlanta Veterans Medical Center, and Emory University Eye Center (Lynch), Atlanta, Georgia, and the Department of Ophthalmology (Radcliffe), Weill Cornell Medical College, New York, New York, USA.
authors.forename: Mary G
authors.initials: MG
authors.lastname: Lynch
authors.affiliation: From the Atlanta Ophthalmology Associates (Brown), Atlanta Veterans Medical Center, and Emory University Eye Center (Lynch), Atlanta, Georgia, and the Department of Ophthalmology (Radcliffe), Weill Cornell Medical College, New York, New York, USA.
authors.forename: Reay H
authors.initials: RH
authors.lastname: Brown
mesh_terms: D018463:Filtering Surgery / Q000379:methods*; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D008866:Microsurgery / Q000379:methods*; D015607:Stents; D014129:Trabecular Meshwork / Q000601:surgery*