title: [The influence of electrosleep therapy on the dynamics of the parameters of biorhythmic hormonal activity in the children presenting with extrasystolic arrhythmia in the course of the spa and resort-based treatment].
abstract: Heart rhythm disorders occupy a leading place in the modern structure of cardiovascular diseases in the children. At present, the role of stress-induced reactions in the development of more than a thousand diseases has been proved. Rehabilitation of systemic manifestations of extrasystolic arrhythmia (EA) in the children is only scarcely described in the literature.
  
  
  OBJECTIVE
  The objective of the present work was to improve the effectiveness of the spa and resort-based treatment of the children presenting with extrasystolic arrhythmia taking advantage of the available information about the different biorhythmic activities of the stress-realizing and stress-limiting systems.
  
  
  METHODS
  The study included 60 children presenting with EA, who received a standard combination of spa and resort-based therapeutic modalities in conjunction with electro-sleep therapy.
  
  
  CONCLUSIONS
  The study revealed desynchronization of the endocrine functions in the children with EA that manifests itself as the increased secretion of cortisol and adrenaline, suppressed melatonin and ACTH production, mismatched daytime and nocturnal hormonal levels. The daily bio-rhythmic profile influenced the formation of circadian-type extra systola in the children. The most unfavorable clinical and electrocardiographic patterns were observed in the children with the mixed and night-type arrhythmia. The complex of rehabilitation measures practiced at the Evpatoriya health resort including electro-sleep therapy made it possible to balance the activities of the stress-limiting and stress-implementing systems of the body in the form of normalization of the altered levels of adaptive hormones, ordering of biorhythmical hormonal relationships, and reduction of the number of extrasystoles. The most pronounced effect of the treatment was observed in the group of children with a rare and day-type of arrhythmia to whom electrosleep was prescribed. It is concluded that the significant decrease in the frequency of night-type and mixed-type extrasystoles under effect of electro-sleeptherapy allows to recommend the treatment modality being considered for the correction of this type of heart rhythm disorders.
authors.forename: N N
authors.initials: NN
authors.lastname: Kaladze
authors.forename: A V
authors.initials: AV
authors.lastname: Shvets
authors.forename: N A
authors.initials: NA
authors.lastname: Revenko
mesh_terms: D000293:Adolescent; D001494:Baths / Q000379:methods*; D005117:Cardiac Complexes, Premature / Q000503:physiopathology* / Q000628:therapy*; D002648:Child; D004580:Electronarcosis / Q000379:methods*; D005260:Female; D006294:Health Resorts; D006801:Humans; D008297:Male