title: Characterization of acute phase proteins and oxidative stress response to road transportation in the dog.
abstract: Haptoglobin (Hp), serum amyloid A (SAA), C-reactive protein (CRP), white blood cells (WBC), reactive oxygen metabolites (ROMs), the antioxidant barrier (Oxy-adsorbent) and thiol groups of plasma compounds (SHp) were measured in ten dogs that had been transported a distance of about 230 km within 2 h (experimental group) and in ten dogs that had not been subjected to road transportation (control group). Blood was collected via cephalic venipuncture before road transportation (T0), after road transportation (T1), and more than 6 (T6) and 24 (T24) hours after road transportation in the experimental group (Group A) and at the same time points in the control group (Group B). The GLM (general linear model) Repeated Measures procedure showed a significant difference between the two groups (P<0.0001) and a significant rise (P<0.0001) in the concentrations of Hp, SAA, CRP, WBC, ROMs, Oxy-adsorbent and SHp after road transportation in Group A, underlining that physiological and homeostatic mechanisms are modified differently at various sampling times.
authors.affiliation: Department of Veterinary Sciences, Polo Universitario Annunziata, University of Messina, 98168, Messina, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Fazio
authors.forename: Stefania
authors.initials: S
authors.lastname: Casella
authors.forename: Claudia
authors.initials: C
authors.lastname: Giannetto
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Giudice
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Piccione
mesh_terms: D000209:Acute-Phase Proteins / Q000378:metabolism*; D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D002097:C-Reactive Protein / Q000378:metabolism; D004285:Dogs / Q000502:physiology* / Q000523:psychology*; D006242:Haptoglobins / Q000378:metabolism; D006706:Homeostasis; D007958:Leukocyte Count; D018384:Oxidative Stress / Q000502:physiology*; D017382:Reactive Oxygen Species / Q000097:blood; D000685:Serum Amyloid A Protein / Q000378:metabolism; D013312:Stress, Physiological / Q000502:physiology; D013315:Stress, Psychological / Q000097:blood*; D013438:Sulfhydryl Compounds / Q000097:blood; D013997:Time Factors; D014186:Transportation / Q000379:methods*
chemical_list: D000209:Acute-Phase Proteins; D000975:Antioxidants; D006242:Haptoglobins; D017382:Reactive Oxygen Species; D000685:Serum Amyloid A Protein; D013438:Sulfhydryl Compounds; D002097:C-Reactive Protein
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