title: Development of a hydrogen peroxide sensor based on screen-printed electrodes modified with inkjet-printed Prussian blue nanoparticles.
abstract: A sensor for the simple and sensitive measurement of hydrogen peroxide has been developed which is based on screen printed electrodes (SPEs) modified with Prussian blue nanoparticles (PBNPs) deposited using piezoelectric inkjet printing. PBNP-modified SPEs were characterized using physical and electrochemical techniques to optimize the PBNP layer thickness and electroanalytical conditions for optimum measurement of hydrogen peroxide. Sensor optimization resulted in a limit of detection of 2 × 10(-7) M, a linear range from 0 to 4.5 mM and a sensitivity of 762 μA ∙ mM(-1) ∙ cm(-2) which was achieved using 20 layers of printed PBNPs. Sensors also demonstrated excellent reproducibility (<5% rsd).
authors.affiliation: Dipartimento di Scienze e Tecnologie Chimiche, Università di Roma Tor Vergata, Via della Ricerca Scientifica 1, Rome 00133, Italy. Stefano.Cinti@uniroma2.it.
authors.forename: Stefano
authors.initials: S
authors.lastname: Cinti
authors.affiliation: Dipartimento di Scienze e Tecnologie Chimiche, Università di Roma Tor Vergata, Via della Ricerca Scientifica 1, Rome 00133, Italy. Fabiana.Arduini@uniroma2.it.
authors.forename: Fabiana
authors.initials: F
authors.lastname: Arduini
authors.affiliation: Dipartimento di Scienze e Tecnologie Chimiche, Università di Roma Tor Vergata, Via della Ricerca Scientifica 1, Rome 00133, Italy. Danila.Moscone@uniroma2.it.
authors.forename: Danila
authors.initials: D
authors.lastname: Moscone
authors.affiliation: Dipartimento di Scienze e Tecnologie Chimiche, Università di Roma Tor Vergata, Via della Ricerca Scientifica 1, Rome 00133, Italy. Giuseppe.Palleschi@uniroma2.it.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Palleschi
authors.affiliation: Department of Biological, Biomedical and Analytical Sciences, Faculty of Health and Applied Sciences, University of the West of England, Coldharbour Lane, Bristol BS16 1QY, UK. tony.killard@uwe.ac.uk.
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Killard
mesh_terms: D055664:Electrochemical Techniques / Q000295:instrumentation* / Q000379:methods*; D004566:Electrodes; D005295:Ferrocyanides / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry*; D057230:Limit of Detection; D053758:Nanoparticles; D011327:Printing / Q000379:methods; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D005295:Ferrocyanides; D006861:Hydrogen Peroxide; C000170:ferric ferrocyanide
references.citation: J Biochem Biophys Methods. 2005 Dec 31;65(2-3):45-80
references.pmid: 16297980
references.citation: Nature. 2009 Jun 18;459(7249):996-9
references.pmid: 19494811
references.citation: Analyst. 2012 Jan 7;137(1):49-58
references.pmid: 22081036
references.citation: Inorg Chem. 2004 Nov 15;43(23):7339-45
references.pmid: 15530083
references.citation: Anal Chim Acta. 2006 Nov 24;580(2):155-62
references.pmid: 17723768
references.citation: Anal Bioanal Chem. 2007 Jul;388(5-6):1049-57
references.pmid: 17508205
references.citation: Analyst. 2010 May;135(5):845-67
references.pmid: 20419231
references.citation: Colloids Surf B Biointerfaces. 2012 Jan 1;89:108-16
references.pmid: 21958538
references.citation: Anal Chim Acta. 2013 May 24;779:56-63
references.pmid: 23663672
references.citation: Biosens Bioelectron. 2007 May 15;22(11):2669-74
references.pmid: 17141494
references.citation: Anal Chem. 2000 Apr 1;72(7):1720-3
references.pmid: 10763276
references.citation: ACS Appl Mater Interfaces. 2010 Aug;2(8):2339-46
references.pmid: 20735106
references.citation: J Pharm Sci. 2012 Mar;101(3):895-913
references.pmid: 22083792
references.citation: Biosens Bioelectron. 2009 Jan 1;24(5):1141-5
references.pmid: 18707863
references.citation: Nature. 2011 Jul 13;475(7356):364-7
references.pmid: 21753752
references.citation: Anal Chem. 2001 Jun 1;73(11):2529-35
references.pmid: 11403295
references.citation: Anal Sci. 2012;28(2):135-40
references.pmid: 22322805
references.citation: Biosens Bioelectron. 2005 Sep 15;21(3):389-407
references.pmid: 16076428
references.citation: J Nanosci Nanotechnol. 2007 Aug;7(8):2877-82
references.pmid: 17685310
references.citation: Talanta. 2005 Mar 31;66(1):86-91
references.pmid: 18969966