title: Alkyne mechanochemistry: putative activation by transoidal bending.
abstract: We investigated the use of mechanical stress to bend carbon-carbon triple bonds. Formation of an isoquinoline after reaction with a benzyl azide trap points towards a nucleophilic addition mechanism, differentiating mechanochemical trans-bending of π bonds from the typical reactivity observed for cisoidal bending of triple bonds in strained cyclic alkynes.
authors.affiliation: Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, USA. jsmoore@illinois.edu.
authors.forename: Charles E
authors.initials: CE
authors.lastname: Diesendruck
authors.forename: Lingyang
authors.initials: L
authors.lastname: Zhu
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Moore