title: Acceptance of standardized ultrasound classification, use of albendazole, and long-term follow-up in clinical management of cystic echinococcosis: a systematic review.
abstract: OBJECTIVE
  Cystic echinococcosis is a chronic, complex, and neglected disease. The need for a simple classification of cyst morphology that would provide an accepted framework for scientific and clinical work on cystic echinococcosis has been addressed by two documents issued by the WHO Informal Working Group on Echinococcosis in 2003 (cyst classification) and in 2010 (Expert consensus for the diagnosis and treatment of echinococcosis).
  
  
  RESULTS
  Here we evaluate the use of the WHO Informal Working Group on Echinococcosis classification of hepatic cystic echinococcosis, the acceptance by clinicians of recommendations regarding the use of albendazole, and the implementation of the long-term follow-up of patients with hepatic cystic echinococcosis in the scientific literature since the WHO Informal Working Group on Echinococcosis recommendations were issued.
  
  
  CONCLUSIONS
  Of the publications included in our review, 71.2% did not indicate any classification, whereas 14% used the WHO Informal Working Group on Echinococcosis classification. Seventy-four percent reported the administration of peri-interventional albendazole, although less than half reported its modality, and 51% the length of patient follow-up. A joint effort is needed from the scientific community to encourage the acceptance and implementation of these three key issues in the clinical management of cystic echinococcosis.
authors.affiliation: aDepartment of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia bDivision of Infectious and Tropical Diseases, 'San Matteo' Hospital Foundation cWHO Collaborating Centre for Clinical Management of Cystic Echinococcosis, Pavia, Italy dSwiss Tropical and Public Health Institutee University of Basel, Basel, Switzerland.
authors.forename: Francesca
authors.initials: F
authors.lastname: Tamarozzi
authors.forename: Giovanni J
authors.initials: GJ
authors.lastname: Nicoletti
authors.forename: Andreas
authors.initials: A
authors.lastname: Neumayr
authors.forename: Enrico
authors.initials: E
authors.lastname: Brunetti
mesh_terms: D015766:Albendazole / Q000627:therapeutic use*; D000871:Anthelmintics / Q000627:therapeutic use*; D004322:Drainage; D004444:Echinococcosis, Hepatic / Q000145:classification / Q000175:diagnosis* / Q000188:drug therapy; D005500:Follow-Up Studies; D006498:Hepatectomy; D006801:Humans; D058069:Neglected Diseases / Q000145:classification / Q000175:diagnosis* / Q000188:drug therapy; D018084:Ultrasonography, Interventional; D014944:World Health Organization
chemical_list: D000871:Anthelmintics; D015766:Albendazole