title: Blood pressure levels and prognosis of intracranial trauma patients with cognitive dysfunction.
abstract: OBJECTIVE
  To evaluate the effects of blood pressure levels on prognosis of intracranial trauma patients with cognitive dysfunction.
  
  
  METHODS
  One hundred and twenty intracranial trauma patients enrolled in our hospital from February 2011 to July 2013 were selected, including 40 hypertension and 80 non-hypertension cases. They were investigated by MiniMental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) scales, and the clinical data were retrospectively analyzed.
  
  
  RESULTS
  Compared with the control group, the MoCA, visuospatial executive function, attention, language, delayed recall, MMSE, orientation and memory scores of the hypertension group were significantly lower. Unconditional Logistic regression analysis showed that age, history of cerebrovascular disease and triglyceride level were the independent risk factors of cognitive function.
  
  
  CONCLUSIONS
  The blood pressure levels of intracranial trauma patients were associated with cognitive function, with age, history of cerebrovascular disease and triglyceride level as the independent risk factors. Therefore, it is necessary to control blood pressure level to improve prognosis.
authors.affiliation: Weiyu Wang, Department of Neurosurgery, Zhejiang Provincial People's Hospital, Hangzhou 310014, China.
authors.forename: Weiyu
authors.initials: W
authors.lastname: Wang
authors.affiliation: Weiyu Wang, Department of Neurosurgery, Zhejiang Provincial People's Hospital, Hangzhou 310014, China.
authors.forename: Junbiao
authors.initials: J
authors.lastname: Fang
authors.affiliation: Bing Lei, Department of Neurosurgery, Zhejiang Provincial People's Hospital, Hangzhou 310014, China.
authors.forename: Bing
authors.initials: B
authors.lastname: Lei
keywords: Blood pressure; Cognitive dysfunction; Intracranial trauma; Risk factor
references.citation: N Engl J Med. 2011 Jul 7;365(1):44-53
references.pmid: 21732836
references.citation: Cochrane Database Syst Rev. 2009 Oct 07;(4):CD004034
references.pmid: 19821318
references.citation: Hypertens Res. 2008 Apr;31(4):673-8
references.pmid: 18633179
references.citation: J Neurosci Res. 2010 Oct;88(13):2889-98
references.pmid: 20544833
references.citation: Hypertension. 2010 Aug;56(2):196-202
references.pmid: 20530299
references.citation: Rev Med Liege. 2008 May-Jun;63(5-6):269-79
references.pmid: 18669192
references.citation: J Am Geriatr Soc. 2009 Jul;57(7):1232-7
references.pmid: 19453303
references.citation: Curr Opin Neurol. 2013 Feb;26(1):29-36
references.pmid: 23254555
references.citation: Am J Hypertens. 2012 Jul;25(7):739-45
references.pmid: 22513830
references.citation: Am J Hypertens. 2011 Mar;24(3):285-91
references.pmid: 21088668
references.citation: Neurology. 2009 Aug 25;73(8):589-95
references.pmid: 19704077
references.citation: J Hypertens. 2008 Aug;26(8):1642-50
references.pmid: 18622244
references.citation: Neurocrit Care. 2012 Sep;17 Suppl 1:S60-5
references.pmid: 22936079
references.citation: Hypertension. 2008 Jan;51(1):99-104
references.pmid: 18025297
references.citation: Neurochem Res. 2010 Dec;35(12):1933-8
references.pmid: 21127967
references.citation: Nat Rev Endocrinol. 2011 Feb;7(2):108-14
references.pmid: 21263438
references.citation: Nurs Res. 2010 Mar-Apr;59(2):127-39
references.pmid: 20216015
references.citation: Int J Cardiol. 2013 Sep 30;168(2):871-80
references.pmid: 23164592