title: Longer incubation times for yeast fungemia: importance for presumptive treatment.
abstract: Isolation rates of Candida glabrata at ≤2 days were 8.9% and 34.8% at >2 days; for Cryptococcus neoformans, they were 0.9% and 8.6%, respectively (1741 fungemia analyzed). An incubation time >2 days supports candins as presumptive treatment for C. glabrata, keeping in mind the risk of Cryptococcus fungemia.
authors.affiliation: Université Paris Descartes-Paris 5, Service de Parasitologie-Mycologie, Hôpital Cochin, APHP, Paris, France. Electronic address: andre.paugam@cch.aphp.fr.
authors.forename: André
authors.initials: A
authors.lastname: Paugam
authors.affiliation: Université Paris Descartes-Paris 5, Service de Parasitologie-Mycologie, Hôpital Cochin, APHP, Paris, France.
authors.forename: Thierry
authors.initials: T
authors.lastname: Ancelle
authors.affiliation: Institut Pasteur, Unité de Mycologie Moléculaire, Centre National de Référence Mycoses Invasives et Antifongiques, Paris, France; CNRS URA3012, Paris, France; Université Paris Descartes-Paris 5, Service de Maladies Infectieuses et Tropicales, Hôpital Necker-Enfants malades, APHP, Centre d'Infectiologie Necker Pasteur, IHU Imagine, Paris, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Lortholary
authors.affiliation: Institut Pasteur, Unité de Mycologie Moléculaire, Centre National de Référence Mycoses Invasives et Antifongiques, Paris, France; Université Paris Diderot- Paris 7, Service de Parasitologie-Mycologie, Hôpital Saint-Louis, APHP, Créteil, France.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Bretagne
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use*; D041221:Candida glabrata / Q000302:isolation & purification*; D003455:Cryptococcus neoformans / Q000302:isolation & purification*; D016469:Fungemia / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D013997:Time Factors
chemical_list: D000935:Antifungal Agents
keywords: automated blood cultures; candidemia; incubation time