title: Cu(II)-mediated ortho C-H alkynylation of (hetero)arenes with terminal alkynes.
abstract: Cu(II)-promoted ortho alkynylation of arenes and heteroarenes with terminal alkynes has been developed to prepare aryl alkynes. A variety of arenes and terminal alkynes bearing different substituents are compatible with this reaction, thus providing an alternative disconnection to Sonogashira coupling.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China.
authors.forename: Ming
authors.initials: M
authors.lastname: Shang
authors.forename: Hong-Li
authors.initials: HL
authors.lastname: Wang
authors.forename: Shang-Zheng
authors.initials: SZ
authors.lastname: Sun
authors.forename: Hui-Xiong
authors.initials: HX
authors.lastname: Dai
authors.forename: Jin-Quan
authors.initials: JQ
authors.lastname: Yu
mesh_terms: D000478:Alkylation; D000480:Alkynes / Q000138:chemical synthesis* / Q000737:chemistry*; D001555:Benzene Derivatives / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D000480:Alkynes; D001555:Benzene Derivatives; D003300:Copper