title: [Comparative evaluation of effectiveness of the combined immunocorrection in patients suffering severe craniocerebral trauma].
abstract: Comparative estimation of clinical efficacy of various immunocorrection schemes for the immune state correction was conducted in 106 patients in conditions ofsevere craniocerebral trauma (SCCT), combined application of immunofan and intravenous laser irradiation of blood (IVLIB). In 32 patients (I group) a standard intensive therapy (SITH) was conducted: in 21 (II group)--immunofan was applied additionally; in 25 (III group)--in addition to SITH IVLIB was conducted; in 28 (IV group)--immunofan solution was infused and sessions of IVLIB (3 - 4 sessions a day) on a background of SITH were conducted. The immunity indices were analyzed on the 1 - 2, 5 - 6-th and 9 -10-th days after trauma. Estimation of the combined therapy efficacy have shown, that in SCCT she renders a significant immunocorrecting effect on the 5 - 6-th days already, on the 9 - 10-th days the immune state parameters were really normalized, reduction of the complications rate by 26% and of lethality by 8.6% was noted.
authors.forename: I Sh
authors.initials: ISh
authors.lastname: Marerrambeĭli
authors.forename: V S
authors.initials: VS
authors.lastname: Mirzoeva
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000328:Adult; D001402:B-Lymphocytes / Q000187:drug effects / Q000276:immunology; D003131:Combined Modality Therapy; D006259:Craniocerebral Trauma / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology / Q000532:radiotherapy*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects / Q000528:radiation effects; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007273:Injections, Intramuscular; D028022:Low-Level Light Therapy; D008297:Male; D008875:Middle Aged; D009842:Oligopeptides / Q000627:therapeutic use*
chemical_list: D000276:Adjuvants, Immunologic; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D009842:Oligopeptides