title: Primary ovarian choriocarcinoma mimicking ectopic pregnancy.
abstract: Nongestational ovarian choriocarcinoma is an exceedingly rare and highly aggressive tumor. Although early diagnosis and timely initiation of therapy is important, it is difficult in reproductive aged patients because of the frequent elevation of human chorionic gonadotropin. We report a primarily nongestational ovarian choriocarcinoma in a 12-year-old virgin female. Initial diagnosis based on abdominopelvic computed tomography and pelvis magnetic resonance imaging was ectopic pregnancy with hemoperitoneum. A diagnostic laparoscopy of the ovarian tumor revealed choriocarcinoma. Unilateral salpingo-oophorectomy and omental sampling revealed surgical stage of IA. Six courses of adjuvant combination chemotherapy (bleomycin, etoposide, and cisplatin) followed surgery.
authors.affiliation: Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Eun Jin
authors.initials: EJ
authors.lastname: Heo
authors.affiliation: Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Chel Hun
authors.initials: CH
authors.lastname: Choi
authors.affiliation: Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Jung Min
authors.initials: JM
authors.lastname: Park
authors.affiliation: Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Jeong-Won
authors.initials: JW
authors.lastname: Lee
authors.affiliation: Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Duk-Soo
authors.initials: DS
authors.lastname: Bae
authors.affiliation: Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Byoung-Gie
authors.initials: BG
authors.lastname: Kim
keywords: Choriocarcinoma; Laparoscopy; Nongestational; Ovary
references.citation: Obstet Gynecol. 2006 May;107(5):1075-85
references.pmid: 16648414
references.citation: Pediatr Int. 2000 Aug;42(4):383-5
references.pmid: 10986872
references.citation: Best Pract Res Clin Obstet Gynaecol. 2012 Jun;26(3):347-55
references.pmid: 22301054
references.citation: Ann Oncol. 2012 Oct;23 Suppl 7:vii20-6
references.pmid: 22997450
references.citation: Chem Biol Interact. 1976 Jul;14(1-2):93-9
references.pmid: 182391
references.citation: Gynecol Oncol. 2005 Mar;96(3):784-91
references.pmid: 15721426
references.citation: J Clin Oncol. 1995 Sep;13(9):2278-80
references.pmid: 7545220
references.citation: Br J Cancer. 2011 Aug 9;105(4):493-7
references.pmid: 21772335
references.citation: Pathol Int. 2006 Oct;56(10):613-6
references.pmid: 16984618