title: Preoperative MRI in patients with locoregional recurrent breast cancer: influence on treatment modalities.
abstract: OBJECTIVE
  The purpose of this analysis was to evaluate the impact of preoperative magnetic resonance imaging (MRI) on management in patients with locoregional recurrent breast cancer.
  
  
  METHODS
  Forty-three patients who underwent treatment for locoregional relapse of breast cancer from 2008 through 2012 were analyzed. All patients underwent both conventional surveillance by mammography, ultrasound, and clinical examination and subsequent bilateral breast MRI.
  
  
  RESULTS
  Preoperative MRI detected additional tumor foci in 15 of 43 patients (34.9%). In two cases (4.7%), the diagnosis of occult sites had no influence on the subsequent treatment. Two patients (4.7%) had an unfavorable change of surgical management with unnecessary additional resection of benign foci. Eleven patients benefited from the MRI scan detecting malignant occult lesions (25.6%) resulting in either additional surgical resection or radiotherapy. Patient and tumor characteristics in primary disease did not differ significantly between patients with a favorable impact on surgical management and patients who experienced either no benefit or even disadvantage from MRI scan.
  
  
  CONCLUSIONS
  Preoperative breast MRI has a strong impact on the management of locoregional recurrent breast cancer. This study demonstrates that breast MRI is a powerful supplement to conventional diagnostic work-up, both during follow-up or preoperative treatment planning in recurrent disease.
authors.affiliation: Department of Obstetrics and Gynecology, Center for Integrated Oncology, University of Bonn, Sigmund-Freud-St 25, 53105 Bonn, Germany.
authors.forename: Anton
authors.initials: A
authors.lastname: Oseledchyk
authors.affiliation: Department of Obstetrics and Gynecology, Center for Integrated Oncology, University of Bonn, Sigmund-Freud-St 25, 53105 Bonn, Germany.
authors.forename: Christina
authors.initials: C
authors.lastname: Kaiser
authors.affiliation: Department of Obstetrics and Gynecology, Center for Integrated Oncology, University of Bonn, Sigmund-Freud-St 25, 53105 Bonn, Germany.
authors.forename: Lisa
authors.initials: L
authors.lastname: Nemes
authors.affiliation: Department of Obstetrics and Gynecology, Center for Integrated Oncology, University of Bonn, Sigmund-Freud-St 25, 53105 Bonn, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Döbler
authors.affiliation: Department of Obstetrics and Gynecology, Center for Integrated Oncology, University of Bonn, Sigmund-Freud-St 25, 53105 Bonn, Germany.
authors.forename: Alina
authors.initials: A
authors.lastname: Abramian
authors.affiliation: Department of Obstetrics and Gynecology, Center for Integrated Oncology, University of Bonn, Sigmund-Freud-St 25, 53105 Bonn, Germany.
authors.forename: Mignon-Denise
authors.initials: MD
authors.lastname: Keyver-Paik
authors.affiliation: Department of Radiology, Center for Integrated Oncology, University of Bonn, Bonn, Germany.
authors.forename: Claudia
authors.initials: C
authors.lastname: Leutner
authors.affiliation: Department of Radiology, Center for Integrated Oncology, University of Bonn, Bonn, Germany.
authors.forename: Hans H
authors.initials: HH
authors.lastname: Schild
authors.affiliation: Department of Obstetrics and Gynecology, Center for Integrated Oncology, University of Bonn, Sigmund-Freud-St 25, 53105 Bonn, Germany.
authors.forename: Walther
authors.initials: W
authors.lastname: Kuhn
authors.affiliation: Department of Obstetrics and Gynecology, Center for Integrated Oncology, University of Bonn, Sigmund-Freud-St 25, 53105 Bonn, Germany. Electronic address: manuel.debald@ukb.uni-bonn.de.
authors.forename: Manuel
authors.initials: M
authors.lastname: Debald
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery*; D019091:Critical Pathways; D003657:Decision Making; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery*; D011300:Preoperative Care / Q000379:methods*; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D019564:Unnecessary Procedures
keywords: Breast MRI; breast cancer; locoregional recurrence; relapse