title: Successful Treatment of a Progressive BRAF V600E-Mutated Anaplastic Pleomorphic Xanthoastrocytoma With Vemurafenib Monotherapy.
authors.affiliation: Center for Neuro-Oncology, Dana-Farber/Brigham and Women's Cancer Center; and Harvard Medical School, Boston, MA eqlee@partners.org.
authors.forename: Eudocia Q
authors.initials: EQ
authors.lastname: Lee
authors.affiliation: Center for Neuro-Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, MA.
authors.forename: Sandra
authors.initials: S
authors.lastname: Ruland
authors.affiliation: Dana-Farber Cancer Institute; and Brigham and Women's Hospital, Boston, MA.
authors.forename: Nicole R
authors.initials: NR
authors.lastname: LeBoeuf
authors.affiliation: Center for Neuro-Oncology, Dana-Farber/Brigham and Women's Cancer Center; and Harvard Medical School, Boston, MA.
authors.forename: Patrick Y
authors.initials: PY
authors.lastname: Wen
authors.affiliation: Harvard Medical School; and Brigham and Women's Hospital, Boston, MA.
authors.forename: Sandro
authors.initials: S
authors.lastname: Santagata
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001254:Astrocytoma / Q000188:drug therapy* / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D004334:Drug Administration Schedule; D003875:Drug Eruptions / Q000209:etiology; D005625:Frontal Lobe / Q000473:pathology; D018698:Glutamic Acid; D006801:Humans; D007211:Indoles / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008279:Magnetic Resonance Imaging; D008297:Male; D009154:Mutation; D009367:Neoplasm Staging; D048493:Proto-Oncogene Proteins B-raf / Q000235:genetics*; D013449:Sulfonamides / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D013702:Temporal Lobe / Q000473:pathology; D016896:Treatment Outcome; D014633:Valine; D000077484:Vemurafenib; D014973:Xanthomatosis / Q000188:drug therapy* / Q000235:genetics* / Q000473:pathology / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents; D007211:Indoles; D013449:Sulfonamides; D000077484:Vemurafenib; D018698:Glutamic Acid; C482119:BRAF protein, human; D048493:Proto-Oncogene Proteins B-raf; D014633:Valine