title: A signal detection analysis of executive control performance among adolescent inhalant and cannabis users.
abstract: BACKGROUND
  Inhalant users have multiple comorbid issues (e.g., polydrug use) that complicate identifying inhalant-specific cognitive deficits.
  
  
  OBJECTIVE
  The aim of the present study was to use signal detection theory to identify inhalant-specific differences in executive control.
  
  
  METHODS
  We examined three well-matched groups: 19 inhalant users, 19 cannabis users, and 19 controls using Stroop and Go/No-Go tasks.
  
  
  RESULTS
  Inhalant users demonstrated significantly lower d-prime scores relative to controls, but not cannabis users, on both tasks, suggesting possible executive deficits relative to controls. CONCLUSIONS/IMPORTANCE: The results of this study raise questions regarding inhalant toxicity and the vulnerability of the adolescent brain to drugs of abuse.
authors.affiliation: 1Department of Psychiatry, Melbourne Neuropsychiatry Centre, University of Melbourne , Melbourne, Victoria , Australia.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Takagi
authors.forename: Dan I
authors.initials: DI
authors.lastname: Lubman
authors.forename: Susan M
authors.initials: SM
authors.lastname: Cotton
authors.forename: Antonio
authors.initials: A
authors.lastname: Verdejo-García
authors.forename: Raquel
authors.initials: R
authors.lastname: Vilar-López
authors.forename: Murat
authors.initials: M
authors.lastname: Yücel
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior / Q000523:psychology*; D000704:Analysis of Variance; D016022:Case-Control Studies; D003071:Cognition; D005260:Female; D006801:Humans; D058545:Inhalant Abuse / Q000523:psychology*; D008297:Male; D002189:Marijuana Abuse / Q000523:psychology*; D009483:Neuropsychological Tests; D011930:Reaction Time; D017603:Signal Detection, Psychological; D057190:Stroop Test; D055815:Young Adult
keywords: Go/No-Go; Stroop; cannabis; cognitive control; d-prime; inhalants; signal detection