title: Comparison of medical issues in antenatal and perinatal periods in early youth, adolescent, and young adult mothers in Taiwan: a 10-year nationwide study.
abstract: BACKGROUND
  Limited information is available concerning investigating the separate effect of teenage childbirth on medical issues in the antenatal and perinatal periods. Therefore, this study aimed to assess medical problems in antenatal and perinatal periods among early youth, adolescent and young adult mothers in Taiwan.
  
  
  METHODS
  This retrospective population-based cohort study was conducted by using data from Taiwan's National Health Insurance Research Database. A total of 335,590 mothers aged less than 25 years who had singleton births were identified between 2002 and 2011. Univariate and multivariate logistic regression analyses were conducted to estimate unadjusted and adjusted odds ratios (OR) and 95% confidence intervals (CI) of each medical problem category in the antenatal and perinatal periods.
  
  
  RESULTS
  Compared with mothers aged 20-24 years, adolescents (16-19 years) and early youth mothers (≤ 15 years), particularly those aged 10-15, had a significantly higher risk of intrauterine growth retardation (IUGR, OR = 1.37, 95% CI: 1.00-1.89) and preterm delivery (OR = 2.98, 95% CI: 2.48-3.58) after adjusting for demographic characteristics and clinical factors. Additionally, adolescents mothers were at an increased risk of anemia (OR = 1.32, 95% CI: 1.24-1.40), oligohydramnios (OR = 1.21, 95% CI: 1.12-1.32), failed labor induction (OR = 1.33, 95% CI: 1.24-1.43), and fetal distress (OR = 1.20, 95% CI: 1.14-1.26) after adjustment.
  
  
  CONCLUSIONS
  Not all young mothers in our study experienced the same magnitude of increased medical problems in the antenatal and perinatal periods. However, a sufficiently higher probability of having IUGR and preterm delivery was observed among early youth and adolescent mothers.
authors.forename: Chun-Che
authors.initials: CC
authors.lastname: Huang
authors.forename: Yung-Chieh
authors.initials: YC
authors.lastname: Lin
authors.affiliation: Master Degree Program in Aging and Long-Term Care, College of Nursing, Kaohsiung Medical University, Kaohsiung, Taiwan. yah@kmu.edu.tw.
authors.forename: Yu-Tung
authors.initials: YT
authors.lastname: Huang
authors.forename: Kuang-Hua
authors.initials: KH
authors.lastname: Huang
mesh_terms: D000293:Adolescent; D000740:Anemia / Q000453:epidemiology; D002648:Child; D005260:Female; D005316:Fetal Distress / Q000453:epidemiology; D005317:Fetal Growth Retardation / Q000453:epidemiology; D006801:Humans; D008423:Maternal Age; D016104:Oligohydramnios / Q000453:epidemiology; D058725:Peripartum Period; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D047928:Premature Birth / Q000453:epidemiology; D012189:Retrospective Studies; D013624:Taiwan / Q000453:epidemiology; D055815:Young Adult
references.citation: Acta Obstet Gynecol Scand. 2004 Dec;83(12):1178-83
references.pmid: 15548152
references.citation: Lancet. 2012 Apr 28;379(9826):1630-40
references.pmid: 22538178
references.citation: Paediatr Perinat Epidemiol. 2003 Oct;17(4):332-9
references.pmid: 14629314
references.citation: Matern Child Health J. 2008 Mar;12(2):149-54
references.pmid: 17562148
references.citation: Eur J Obstet Gynecol Reprod Biol. 2009 Dec;147(2):151-6
references.pmid: 19733429
references.citation: Am J Public Health. 1995 Aug;85(8 Pt 1):1143-6
references.pmid: 7625515
references.citation: BMC Public Health. 2006 Oct 09;6:246
references.pmid: 17029640
references.citation: Pediatr Int. 2010 Jun;52(3):447-52
references.pmid: 19863752
references.citation: Br J Clin Pharmacol. 2012 Aug;74(2):362-9
references.pmid: 22435711
references.citation: Paediatr Perinat Epidemiol. 2012 Jul;26 Suppl 1:259-84
references.pmid: 22742615
references.citation: Asia Pac J Public Health. 2007;19(1):40-2
references.pmid: 17784658
references.citation: Int J Gynaecol Obstet. 2001 Nov;75(2):111-21
references.pmid: 11684107
references.citation: Am J Obstet Gynecol. 2005 Feb;192(2):342-9
references.pmid: 15695970
references.citation: J Pediatr Adolesc Gynecol. 2010 Jun;23(3):142-5
references.pmid: 19822446
references.citation: Child Care Health Dev. 2010 Mar;36(2):232-40
references.pmid: 20047601
references.citation: BMC Pregnancy Childbirth. 2010 Jul 09;10:36
references.pmid: 20618921
references.citation: BMC Pregnancy Childbirth. 2013 Nov 09;13:204
references.pmid: 24207112
references.citation: J Matern Fetal Neonatal Med. 2013 Mar;26(5):469-72
references.pmid: 23057873
references.citation: Lancet. 2011 Dec 17;378(9809):2123-35
references.pmid: 21813172
references.citation: Am J Ind Med. 2008 Dec;51(12):911-22
references.pmid: 18942663
references.citation: Int J Epidemiol. 2007 Apr;36(2):368-73
references.pmid: 17213208
references.citation: Arch Gynecol Obstet. 2012 Mar;285(3):573-7
references.pmid: 21789518
references.citation: J Pediatr Adolesc Gynecol. 2008 Feb;21(1):17-9
references.pmid: 18312795