title: Comparison of Artecoll, Restylane and silicone for augmentation rhinoplasty in 378 Chinese patients.
abstract: OBJECTIVE
  Dermal fillers have been proven to be safe in soft tissue augmentation; however, their efficacy in modeling the noses of Asian patients has not been demonstrated.
  
  
  METHODS
  In this study, 378 patients were included and underwent augmentation rhinoplasty (Artecoll, n=126; Restylane, n=126 and silicone implants, n=126). The subjective and objective outcomes were evaluated on day 1, and months 1, 3, 6, and 12 after injection rhinoplasty.
  
  
  RESULTS
  All patients achieved significant improvement in nasal shape and contour immediately after surgery. Patients treated with Restylane failed to maintain the nasal shape and contour 1 year after surgery, whereas patients undergoing Artecoll rhinoplasty completely maintained the post-treatment nasal shape and contour. More patients with silicone implants experienced adverse events and the severity of these events was greater in the silicone group compared to those in the Restylane and Acetoll groups.
  
  
  CONCLUSIONS
  Artecoll rhinoplasty has a low incidence of adverse effects and the shape and contour of the nose are maintained for a prolonged period.
authors.forename: Liang
authors.initials: L
authors.lastname: Chen
authors.forename: Shi-Rong
authors.initials: SR
authors.lastname: Li
authors.forename: Pan
authors.initials: P
authors.lastname: Yu
authors.affiliation: . wangzhenxiang0915@163.com.
authors.forename: Zhen-Xiang
authors.initials: ZX
authors.lastname: Wang
mesh_terms: D000328:Adult; D044466:Asian People; D003094:Collagen / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male; D019904:Polymethyl Methacrylate / Q000009:adverse effects / Q000627:therapeutic use; D019736:Prostheses and Implants; D012225:Rhinoplasty / Q000009:adverse effects / Q000379:methods*; D012828:Silicones / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: C445359:Artecoll; D012828:Silicones; D006820:Hyaluronic Acid; D003094:Collagen; D019904:Polymethyl Methacrylate; C445361:Restylane