title: Cognitive function in patients with alcoholic and nonalcoholic chronic liver disease.
abstract: The aim of the present study was to characterize the neurophysiological profile of cognitive impairment associated with patients with chronic alcoholic and nonalcoholic liver disease. The authors evaluated 43 patients with cirrhotic liver disease: 19 patients with chronic alcohol ingestion and 24 nonalcoholic patients who had been infected with hepatitis B or C virus. Eleven healthy subjects were included as control subjects. A battery of 12 psychological tests was used to investigate cognitive deficits in the patients with chronic liver disease. It was observed that alcoholic patients with chronic liver disease showed a more important cognitive deterioration than those affected by hepatitis B or C virus.
authors.forename: Carlos
authors.initials: C
authors.lastname: Brodersen
authors.forename: Eduardo
authors.initials: E
authors.lastname: Koen
authors.forename: Alicia
authors.initials: A
authors.lastname: Ponte
authors.forename: Silvina
authors.initials: S
authors.lastname: Sánchez
authors.forename: Eduardo
authors.initials: E
authors.lastname: Segal
authors.forename: Alberto
authors.initials: A
authors.lastname: Chiapella
authors.forename: Maria
authors.initials: M
authors.lastname: Fernández
authors.forename: Maria
authors.initials: M
authors.lastname: Torres
authors.forename: Valeria
authors.initials: V
authors.lastname: Tripodi
authors.forename: Abraham
authors.initials: A
authors.lastname: Lemberg
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000378:metabolism*; D000704:Analysis of Variance; D002908:Chronic Disease; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000209:etiology; D008103:Liver Cirrhosis / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D055815:Young Adult