title: Expanding the functional role of long noncoding RNAs.
abstract: New findings bring to light a previously unappreciated mechanism involved in the regulation of the oncoprotein MYC. Interesting observations find that the long noncoding RNA (lncRNA) PVT1 is active in controlling levels of MYC through regulation of MYC protein stability.
authors.affiliation: Department of Oncology and Pathology, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
authors.forename: Per
authors.initials: P
authors.lastname: Johnsson
authors.affiliation: 1] Biotechnology and Biomedical Sciences, The University of New South Wales, NSW 2052, Sydney, Australia [2] Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
authors.forename: Kevin V
authors.initials: KV
authors.lastname: Morris
mesh_terms: D000818:Animals; D056915:DNA Copy Number Variations / Q000235:genetics*; D005784:Gene Amplification / Q000235:genetics*; D018628:Gene Dosage / Q000235:genetics*; D016259:Genes, myc / Q000235:genetics*; D006801:Humans; D016274:Oncogene Protein p55(v-myc) / Q000235:genetics*; D062085:RNA, Long Noncoding / Q000235:genetics*
chemical_list: D016274:Oncogene Protein p55(v-myc); D062085:RNA, Long Noncoding
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