title: The principle of membrane fusion in the cell (Nobel lecture).
abstract: Cells contain small membrane-enclosed vesicles which transport many kinds of cargo between the compartments of the cell. The result is a choreographed program of secretory, biosynthetic, and endocytic protein traffic that serves the cell's internal physiologic needs.
authors.affiliation: Department of Cell Biology, Yale University, 333 Cedar Street, CT 06520 New Haven (USA).
authors.forename: James Edward
authors.initials: JE
authors.lastname: Rothman
mesh_terms: D000818:Animals; D002477:Cells / Q000166:cytology* / Q000378:metabolism*; D006801:Humans; D008561:Membrane Fusion; D009613:Nobel Prize
keywords: Nobel lecture; SNARE; cellular biology; membrane fusion; vesicle transport