title: acACS: improving the prediction accuracy of protein subcellular locations and protein classification by incorporating the average chemical shifts composition.
abstract: The chemical shift is sensitive to changes in the local environments and can report the structural changes. The structure information of a protein can be represented by the average chemical shifts (ACS) composition, which has been broadly applied for enhancing the prediction accuracy in protein subcellular locations and protein classification. However, different kinds of ACS composition can solve different problems. We established an online web server named acACS, which can convert secondary structure into average chemical shift and then compose the vector for representing a protein by using the algorithm of auto covariance. Our solution is easy to use and can meet the needs of users.
authors.affiliation: Department of Physics, School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China.
authors.forename: Guo-Liang
authors.identifier: 0000-0003-0943-6129
authors.initials: GL
authors.lastname: Fan
authors.affiliation: Department of Physics, School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China.
authors.forename: Yan-Ling
authors.initials: YL
authors.lastname: Liu
authors.affiliation: The Key Laboratory of Mammalian Reproductive Biology and Biotechnology of the Ministry of Education, College of Life Sciences, Inner Mongolia University, Hohhot 010021, China.
authors.forename: Yong-Chun
authors.identifier: 0000-0002-4953-2337
authors.initials: YC
authors.lastname: Zuo
authors.affiliation: Department of Physics, School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China.
authors.forename: Han-Xue
authors.initials: HX
authors.lastname: Mei
authors.affiliation: Department of Physics, School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Rang
authors.affiliation: Department of Physics, School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China.
authors.forename: Bao-Yan
authors.initials: BY
authors.lastname: Hou
authors.affiliation: Department of Physics, School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D000465:Algorithms; D042541:Intracellular Space / Q000378:metabolism*; D008954:Models, Biological; D008956:Models, Chemical; D017433:Protein Structure, Secondary; D021381:Protein Transport; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D011506:Proteins
references.citation: PLoS One. 2012;7(9):e46633
references.pmid: 23029559
references.citation: J Theor Biol. 2007 Sep 21;248(2):377-81
references.pmid: 17572445
references.citation: J Bioinform Comput Biol. 2010 Oct;8(5):867-84
references.pmid: 20981892
references.citation: J Theor Biol. 2009 Jul 21;259(2):361-5
references.pmid: 19328812
references.citation: J Theor Biol. 2014 Sep 7;356:30-5
references.pmid: 24732262
references.citation: Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W496-502
references.pmid: 18515350
references.citation: J Theor Biol. 2001 Dec 7;213(3):493-502
references.pmid: 11735294
references.citation: J Mol Biol. 1991 Nov 20;222(2):311-33
references.pmid: 1960729
references.citation: Biomed Res Int. 2013;2013:263829
references.pmid: 24027753
references.citation: J Theor Biol. 2014 Sep 7;356:213-22
references.pmid: 24819464
references.citation: Int J Mol Sci. 2014 Feb 26;15(3):3495-506
references.pmid: 24577312
references.citation: Mol Biosyst. 2014 Aug;10(8):2229-35
references.pmid: 24931825
references.citation: J Theor Biol. 2012 Jul 7;304:88-95
references.pmid: 22459701
references.citation: J Theor Biol. 2011 Mar 21;273(1):236-47
references.pmid: 21168420
references.citation: Biophys J. 2003 Feb;84(2 Pt 1):1223-7
references.pmid: 12547802
references.citation: Mol Cell Biol Res Commun. 2000 Sep;4(3):172-3
references.pmid: 11281732
references.citation: Amino Acids. 2007 Jul;33(1):69-74
references.pmid: 17235454
references.citation: Biochem Biophys Res Commun. 2003 May 30;305(2):407-11
references.pmid: 12745090
references.citation: Nat Protoc. 2007;2(4):953-71
references.pmid: 17446895
references.citation: Protein Pept Lett. 2008;15(3):286-9
references.pmid: 18336359
references.citation: Amino Acids. 2012 Aug;43(2):545-55
references.pmid: 22102053
references.citation: J Biomol NMR. 2012 Dec;54(4):355-76
references.pmid: 23086713
references.citation: J Cell Biochem. 2006 Oct 1;99(2):517-27
references.pmid: 16639720
references.citation: Anal Biochem. 2014 Aug 1;458:14-9
references.pmid: 24802134
references.citation: Bioinformatics. 2001 Mar;17(3):282-3
references.pmid: 11294794
references.citation: Nucleic Acids Res. 2000 Jan 1;28(1):235-42
references.pmid: 10592235
references.citation: Bioinformatics. 2006 May 15;22(10):1158-65
references.pmid: 16428265
references.citation: Amino Acids. 2008 May;34(4):653-60
references.pmid: 18175047
references.citation: J Biomol NMR. 1991 Sep;1(3):217-36
references.pmid: 1841696
references.citation: BMC Bioinformatics. 2014;15 Suppl 2:S3
references.pmid: 24564580
references.citation: J Theor Biol. 2013 Oct 7;334:45-51
references.pmid: 23770403
references.citation: Parasit Vectors. 2014 May 27;7:242
references.pmid: 24884876
references.citation: Bioinformatics. 2005 Apr 15;21(8):1719-20
references.pmid: 15585524
references.citation: J Biomol NMR. 2007 Jul;38(3):221-35
references.pmid: 17558470
references.citation: BMC Bioinformatics. 2007 Jun 14;8:201
references.pmid: 17570843
references.citation: J Biomol NMR. 2012 Jun;53(2):125-38
references.pmid: 22534787
references.citation: BMC Bioinformatics. 2007 Sep 13;8:337
references.pmid: 17854501
references.citation: Bioinformatics. 2008 Nov 1;24(21):2512-7
references.pmid: 18728042
references.citation: Biochem Biophys Res Commun. 2004 Aug 6;320(4):1236-9
references.pmid: 15249222
references.citation: Brief Funct Genomic Proteomic. 2008 Jan;7(1):63-73
references.pmid: 18283051
references.citation: J Proteome Res. 2006 Aug;5(8):1888-97
references.pmid: 16889410
references.citation: Biopolymers. 1983 Dec;22(12):2577-637
references.pmid: 6667333
references.citation: Anal Biochem. 2012 Jun 15;425(2):117-9
references.pmid: 22459120
references.citation: Mol Inform. 2013 Oct;32(9-10):775-82
references.pmid: 27480230
references.citation: J Biomol NMR. 2011 May;50(1):43-57
references.pmid: 21448735
references.citation: J Biomol NMR. 2012 Nov;54(3):237-43
references.pmid: 23007199
references.citation: BMC Bioinformatics. 2008 Dec 01;9:510
references.pmid: 19046430
references.citation: Biomed Res Int. 2014;2014:286419
references.pmid: 24991545
references.citation: Bioinformatics. 2014 Feb 15;30(4):472-9
references.pmid: 24318998
references.citation: Nucleic Acids Res. 2007 Jul;35(Web Server issue):W585-7
references.pmid: 17517783
references.citation: J Biomol NMR. 2007 Aug;38(4):289-302
references.pmid: 17610132
references.citation: BMC Bioinformatics. 2006 Nov 30;7:518
references.pmid: 17134515
references.citation: Pac Symp Biocomput. 2008;:604-15
references.pmid: 18229719
references.citation: Bioinformatics. 2003 Nov 1;19(16):2054-64
references.pmid: 14594710