title: In search of next generation antimalarials.
abstract: Compounds 7-10 displayed potency without any apparent toxicity, in animal models of both relapsing and non-relapsing forms of malaria offering hope of a single molecule that can cure both relapsing and non relapsing forms of malaria.
authors.affiliation: Franklin Research Center, Norristown, PA 19403, USA. Electronic address: Sankar.Chatterjee24@gmail.com.
authors.forename: Sankar
authors.initials: S
authors.lastname: Chatterjee
authors.affiliation: Franklin Research Center, Norristown, PA 19403, USA.
authors.forename: Keiichi
authors.initials: K
authors.lastname: Tanabe
authors.affiliation: Franklin Research Center, Norristown, PA 19403, USA.
authors.forename: Edward A
authors.initials: EA
authors.lastname: Nodiff
mesh_terms: D000818:Animals; D000962:Antimalarials / Q000009:adverse effects / Q000737:chemistry / Q000494:pharmacology*; D037621:Artemisinins / Q000009:adverse effects / Q000737:chemistry / Q000494:pharmacology*; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D055808:Drug Discovery; D008253:Macaca mulatta; D008288:Malaria / Q000188:drug therapy*; D015394:Molecular Structure; D021261:Parasitic Sensitivity Tests; D010961:Plasmodium / Q000187:drug effects*; D013329:Structure-Activity Relationship
chemical_list: D000962:Antimalarials; D037621:Artemisinins; C031327:artemisinin
keywords: Malaria; Plasmodium; Primaquine; Quinoline