title: Synthetic biology for therapeutic applications.
abstract: Synthetic biology is a relatively new field with the key aim of designing and constructing biological systems with novel functionalities. Today, synthetic biology devices are making their first steps in contributing new solutions to a number of biomedical challenges, such as emerging bacterial antibiotic resistance and cancer therapy. This review discusses some synthetic biology approaches and applications that were recently used in disease mechanism investigation and disease modeling, drug discovery and production, as well as vaccine development and treatment of infectious diseases, cancer, and metabolic disorders.
authors.affiliation: Department of Biochemistry, ‡Department of Chemical and Biomolecular Engineering, and §Department of Bioengineering, Department of Chemistry, Center for Biophysics and Computational Biology and Institute for Genomic Biology, University of Illinois at Urbana-Champaign , 600 South Mathews Avenue, Urbana, Illinois 61801, United States.
authors.forename: Zhanar
authors.initials: Z
authors.lastname: Abil
authors.forename: Xiong
authors.initials: X
authors.lastname: Xiong
authors.forename: Huimin
authors.initials: H
authors.lastname: Zhao
mesh_terms: D000818:Animals; D055808:Drug Discovery / Q000379:methods; D006801:Humans; D058615:Synthetic Biology / Q000379:methods*
keywords: cancer treatment; disease mechanism; drug discovery; infectious diseases; metabolic disorders; synthetic biology; therapeutic treatment; vaccine development
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