title: Characteristics of Patients With Diabetes Having Normal Coronary Arteries.
abstract: We evaluated the association between risk variables in diabetic patients with normal and diseased coronary arteries in a retrospective cohort study conducted at Rashid Hospital, Dubai. A total of 4446 patients underwent coronary angiography due to various indications; 43% had type 2 diabetes mellitus (T2DM). Among the diabetic patients, 94% had diseased coronary arteries and the remaining 6% had absolutely normal arteries. The normal coronary group had significantly lower low-density lipoprotein cholesterol (LDL-C) and a higher high-density lipoprotein cholesterol (HDL-C) levels than the diseased group. Patients with normal coronaries were more likely to be females, have T2DM for a shorter duration, and were nonsmokers and non-South Asians. They also had lower levels of LDL, hemoglobin A1c, and fasting glucose and higher levels of HDL-C. Apart from these variables, genetic or environmental factors could protect these patients from atherosclerosis.
authors.affiliation: Cardiology Department, Rashid Hospital, Dubai, United Arab Emirates.
authors.forename: Azan Salim
authors.initials: AS
authors.lastname: Binbrek
authors.affiliation: Cardiology Department, Rashid Hospital, Dubai, United Arab Emirates pmsameera@gmail.com.
authors.forename: Sameera Mohamed
authors.initials: SM
authors.lastname: Ali
authors.affiliation: Cardiology Department, Rashid Hospital, Dubai, United Arab Emirates.
authors.forename: Fahad Omar
authors.initials: FO
authors.lastname: Baslaib
authors.affiliation: Cardiology Department, Sheikh Khalifa Hospital, Abudhabi, United Arab Emirates.
authors.forename: Alawi Al Sheikh
authors.initials: AA
authors.lastname: Ali
mesh_terms: D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000032:analysis; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000097:blood / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000517:prevention & control*; D003331:Coronary Vessels / Q000000981:diagnostic imaging; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000000981:diagnostic imaging / Q000453:epidemiology*; D003925:Diabetic Angiopathies / Q000097:blood / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000517:prevention & control*; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D015995:Prevalence; D065840:Protective Factors; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D012737:Sex Factors; D013997:Time Factors; D014479:United Arab Emirates / Q000453:epidemiology
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human
keywords: coronary angiography; coronary atherosclerosis; diseased coronaries; normal coronaries; type 2 diabetes mellitus