title: Respiratory hospitalizations of children and residential exposure to traffic air pollution in Jerusalem.
abstract: Although exposure to traffic-related air pollution has been reported to be associated with respiratory morbidity in children, this association has not been examined in Israel. Jerusalem is ranked among the leading Israeli cities in transport-related air pollution. This case-control study examined whether pediatric hospitalization for respiratory diseases in Jerusalem is related to residential exposure to traffic-related air pollution. Cases (n=4844) were Jerusalem residents aged 0-14 years hospitalized for respiratory illnesses between 2000 and 2006. These were compared to children admitted electively (n=2161) or urgently (n=3085) for non-respiratory conditions. Individual measures of exposure included distance from residence to nearest main road, the total length of main roads, traffic volume, and bus load within buffers of 50, 150, and 300m around each address. Cases were more likely to have any diesel buses passing within 50m of their home (adjusted odds ratios=1.16 and 1.10, 95% confidence intervals 1.04-1.30 and 1.01-1.20 for elective and emergency controls, respectively). Our findings indicated that older girls (5-14) and younger boys (0-4) had increased risks of respiratory hospitalization, albeit with generally widened confidence intervals due to small sample sizes. Our results add to the limited body of evidence regarding associations between diesel exhaust particles and respiratory morbidity. The findings also point to possible differential associations between traffic-related air pollution and pediatric hospitalization among boys and girls in different age groups.
authors.affiliation: Department of Statistics, The Hebrew University of Jerusalem, Jerusalem, Israel. Electronic address: nirelr@mail.huji.ac.il.
authors.forename: Ronit
authors.initials: R
authors.lastname: Nirel
authors.affiliation: Hebrew University - Hadassah Braun School of Public Health and Community Medicine, Jerusalem, Israel.
authors.forename: Michal
authors.initials: M
authors.lastname: Schiff
authors.affiliation: Hebrew University - Hadassah Braun School of Public Health and Community Medicine, Jerusalem, Israel.
authors.forename: Ora
authors.initials: O
authors.lastname: Paltiel
mesh_terms: D000293:Adolescent; D000393:Air Pollutants / Q000633:toxicity*; D000397:Air Pollution / Q000032:analysis; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D004781:Environmental Exposure; D005260:Female; D006760:Hospitalization; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007557:Israel; D008297:Male; D016017:Odds Ratio; D012140:Respiratory Tract Diseases / Q000175:diagnosis / Q000209:etiology*; D001335:Vehicle Emissions / Q000032:analysis
chemical_list: D000393:Air Pollutants; D001335:Vehicle Emissions
keywords: Air pollution; Case–control study; Child; Diesel bus; Hospitalization; Respiratory disease