title: Arterial stiffness and pulse wave reflection are increased in patients suffering from severe periodontitis.
abstract: OBJECTIVE
  This single blind cross-sectional study compared the vascular health of subjects suffering from severe chronic periodontitis, severe aggressive periodontitis and periodontal healthy controls by evaluating pulse wave velocity (PWV), augmentation index (AIx) and pulse pressure amplification (PPA).
  
  
  METHODS
  In a total of 158 subjects, 92 suffering from severe periodontitis and 66 matched periodontal healthy controls, PWV, AIx, central and peripheral blood pressure were recorded using an oscillometric device (Arteriograph).
  
  
  RESULTS
  Subjects suffering from severe chronic or aggressive periodontitis exhibited significantly higher PWV (p = 0.00004), higher AIx (p = 0.0049) and lower PPA (p = 0.028) than matched periodontal healthy controls.
  
  
  CONCLUSIONS
  The results of this study confirm the association between periodontal inflammation and increased cardiovascular risk shown by impaired vascular health in case of severe periodontitis. As impaired vascular health is a common finding in patients suffering from severe periodontal disease a concomitant routine cardiovascular evaluation may be advised.
authors.affiliation: Department of Periodontology, University Hospital Wuerzburg, Wuerzburg, Germany.
authors.forename: Yvonne
authors.initials: Y
authors.lastname: Jockel-Schneider
authors.affiliation: Department of Periodontology, University Hospital Muenster, Muenster, Germany.
authors.forename: Inga
authors.initials: I
authors.lastname: Harks
authors.affiliation: Department of Periodontology, University Hospital Wuerzburg, Wuerzburg, Germany.
authors.forename: Imme
authors.initials: I
authors.lastname: Haubitz
authors.affiliation: Department of Periodontology, University Hospital Wuerzburg, Wuerzburg, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Fickl
authors.affiliation: Department of Periodontology, University Hospital Wuerzburg, Wuerzburg, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Eigenthaler
authors.affiliation: Department of Periodontology, University Hospital Wuerzburg, Wuerzburg, Germany.
authors.forename: Ulrich
authors.initials: U
authors.lastname: Schlagenhauf
authors.affiliation: Clinic of Internal Medicine II, University Hospital Schleswig-Holstein, Luebeck, Germany.
authors.forename: Johannes
authors.initials: J
authors.lastname: Baulmann
mesh_terms: D000328:Adult; D000368:Aged; D001011:Aorta / Q000503:physiopathology; D001794:Blood Pressure; D002908:Chronic Disease; D003430:Cross-Sectional Studies; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009991:Oscillometry; D010518:Periodontitis / Q000175:diagnosis / Q000503:physiopathology*; D063177:Pulse Wave Analysis; D012307:Risk Factors; D012720:Severity of Illness Index; D059289:Vascular Stiffness
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