title: The relationship between daily urinary sodium excretion and metabolic syndrome in patients with kidney transplantation.
abstract: BACKGROUND
  The aim of this study was to determine whether there is a relationship between daily urinary sodium excretion and metabolic syndrome in kidney transplantation patients.
  
  
  METHODS
  This cross-sectional study included 76 adult renal transplantation recipients. To calculate urinary sodium excretion, 24-h urine samples were collected. Metabolic syndrome was diagnosed according to Adult Treatment Panel III (ATP III) criteria updated in a statement from the American Heart Association (AHA)/National Heart, Lung, and Blood Institute (NHLBI) in 2005.
  
  
  RESULTS
  Mean age of the 76 patients was 38 ± 10 years; 21 of the 76 patients were female. Metabolic syndrome was found in 52 (68.4%) of the 76 renal transplantation patients. Mean daily urinary sodium excretion was 190 ± 102 mmol/day, which is equal to a salt intake of 11.1 g/day. Daily urinary sodium excretion was significantly higher in patients with metabolic syndrome compared to those without metabolic syndrome (209 ± 112 mmol/day and 150 ± 62 mmol/day, respectively, p: 0.005). Daily urinary sodium excretion correlated with diastolic blood pressure (r: 0.254, p: 0.028), serum glucose concentration (r: 0.446, p: <0.001), and creatinine clearance (r: 478, p: <0.001). In addition, although there was no significant correlation between daily urinary sodium excretion and systolic blood pressure, the statistical significance was borderline (r: 0.221, p: 0.056).
  
  
  CONCLUSIONS
  There is a significant relationship between daily urinary sodium excretion and metabolic syndrome in renal transplant recipients. The Turkish kidney transplantation patients consume a great amount of salt and salt intake is positively correlated with blood pressure.
authors.affiliation: Department of Nephrology, Erciyes University Medical School, Kayseri, Turkey.
authors.forename: Aydin
authors.initials: A
authors.lastname: Unal
authors.affiliation: Department of Nephrology, Erciyes University Medical School, Kayseri, Turkey.
authors.forename: Ismail
authors.initials: I
authors.lastname: Kocyigit
authors.affiliation: Department of Nephrology, Erciyes University Medical School, Kayseri, Turkey.
authors.forename: Murat Hahri
authors.initials: MH
authors.lastname: Sipahioglu
authors.affiliation: Department of Nephrology, Erciyes University Medical School, Kayseri, Turkey.
authors.forename: Bulent
authors.initials: B
authors.lastname: Tokgoz
authors.affiliation: Department of Nephrology, Erciyes University Medical School, Kayseri, Turkey.
authors.forename: Oktay
authors.initials: O
authors.lastname: Oymak
mesh_terms: D000328:Adult; D001794:Blood Pressure; D003404:Creatinine / Q000378:metabolism; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D024821:Metabolic Syndrome / Q000209:etiology* / Q000503:physiopathology / Q000652:urine*; D008875:Middle Aged; D012307:Risk Factors; D012964:Sodium / Q000652:urine*; D017673:Sodium Chloride, Dietary / Q000008:administration & dosage; D014421:Turkey
chemical_list: D017673:Sodium Chloride, Dietary; D012964:Sodium; D003404:Creatinine