title: Bilateral choroidal osteoma with choroidal neovascular membrane treated with bevacizumab in a child.
abstract: Choroidal osteoma is a rare benign tumor. We report a male child diagnosed with bilateral choroidal osteoma, high myopia and secondary choroidal neovascularization (CNV) membrane in one eye. Co-existence of posterior staphyloma made the clinical diagnosis of choroidal osteoma difficult due to the osteoma filling the depression of the posterior staphyloma. Typical findings on fundus fluorescein angiography, optical coherence tomography, B-scan and indocyanine green angiography confirmed the diagnosis. A review of literature was performed. CNV secondary to choroidal osteoma was treated with intravitreal bevacizumab and it responded well. Regular follow-up is essential for recurrence of CNV and decalcification of the osteoma.
authors.affiliation: Department of Vitreoretina, Dr. Shroff's Charity Eye Hospital, Daryaganj, New Delhi, India.
authors.forename: Manisha
authors.initials: M
authors.lastname: Agarwal
authors.affiliation: Department of Vitreoretina, Dr. Shroff's Charity Eye Hospital, Daryaganj, New Delhi, India.
authors.forename: Meha
authors.initials: M
authors.lastname: Kantha
authors.affiliation: Department of Vitreoretina, Dr. Shroff's Charity Eye Hospital, Daryaganj, New Delhi, India.
authors.forename: Rahul
authors.initials: R
authors.lastname: Mayor
authors.affiliation: Department of Vitreoretina, Dr. Shroff's Charity Eye Hospital, Daryaganj, New Delhi, India.
authors.forename: Ramesh
authors.initials: R
authors.lastname: Venkatesh
authors.affiliation: Department of Vitreoretina, Dr. Shroff's Charity Eye Hospital, Daryaganj, New Delhi, India.
authors.forename: Cyrus M
authors.initials: CM
authors.lastname: Shroff
mesh_terms: D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use*; D000068258:Bevacizumab; D002648:Child; D002828:Choristoma / Q000175:diagnosis / Q000188:drug therapy*; D002830:Choroid Neoplasms / Q000175:diagnosis / Q000188:drug therapy*; D020256:Choroidal Neovascularization / Q000175:diagnosis / Q000188:drug therapy*; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D010016:Osteoma / Q000175:diagnosis / Q000188:drug therapy*; D041623:Tomography, Optical Coherence / Q000379:methods; D042461:Vascular Endothelial Growth Factor A / Q000037:antagonists & inhibitors
chemical_list: D020533:Angiogenesis Inhibitors; D061067:Antibodies, Monoclonal, Humanized; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A; D000068258:Bevacizumab
keywords: Bevacizumab; Choroidal Neovascular Membrane; Choroidal Osteoma
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