title: Ocular flutter as the presenting sign of lung adenocarcinoma.
abstract: Ocular flutter is a rare ophthalmic finding that could represent paraneoplastic phenomena. In adults it is most commonly associated with small cell lung cancer (SCLC). Most patients also present with other neurological defects. We report the case of a 75-year-old woman who presented with isolated ocular flutter. The ensuing workup was significant for an early lung adenocarcinoma that would not have been biopsied otherwise due to its small size. To our knowledge, this is the first reported case of isolated ocular flutter as the presenting symptom of non-SCLC.
authors.affiliation: Neuro-Ophthalmology Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts.
authors.forename: Joshua M
authors.initials: JM
authors.lastname: Kruger
authors.affiliation: Neuro-Ophthalmology Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Yonekawa
authors.affiliation: Neuro-Ophthalmology Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts.
authors.forename: Philip
authors.initials: P
authors.lastname: Skidd
authors.affiliation: Neuro-Ophthalmology Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts.
authors.forename: Dean M
authors.initials: DM
authors.lastname: Cestari
mesh_terms: D000230:Adenocarcinoma / Q000150:complications*; D000077192:Adenocarcinoma of Lung; D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D009759:Nystagmus, Pathologic / Q000209:etiology*; D059545:Paraneoplastic Syndromes, Ocular / Q000209:etiology*
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