title: Serum oxidative stress, visfatin and apelin in healthy women and those with premenstrual syndrome.
abstract: The aim of this study was to investigate whether there is a relationship between premenstrual syndrome and oxidative stress, visfatin and apelin. The study included 40 women with premenstrual syndrome and 40 healthy women. In all subjects, serum visfatin, apelin and oxidative stress parameters were studied in venous blood samples. The oxidative stress parameters were higher in the premenstrual syndrome group than among the controls, but this difference did not reach statistical significance (p > 0.05). It was found that total antioxidant capacity was similar in both groups. For the insulin-serotonin cycle markers, no significant difference was found between groups in terms of visfatin level (p = 0.893), although apelin was found to be significantly higher in the premenstrual syndrome group when compared with the controls (p < 0.001). According to our results, apelin can be used as an ancillary laboratory test in the diagnosis of premenstrual syndrome.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Harran University , Sanliurfa , Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Incebiyik
authors.forename: A
authors.initials: A
authors.lastname: Camuzcuoglu
authors.forename: N Gul
authors.initials: NG
authors.lastname: Hilali
authors.forename: T
authors.initials: T
authors.lastname: Ulas
authors.forename: M
authors.initials: M
authors.lastname: Vural
authors.forename: H
authors.initials: H
authors.lastname: Camuzcuoglu
authors.forename: N
authors.initials: N
authors.lastname: Aksoy
mesh_terms: D000293:Adolescent; D000328:Adult; D000975:Antioxidants; D000073861:Apelin; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000097:blood*; D008875:Middle Aged; D054409:Nicotinamide Phosphoribosyltransferase / Q000097:blood*; D018384:Oxidative Stress; D011293:Premenstrual Syndrome / Q000097:blood* / Q000175:diagnosis; D013438:Sulfhydryl Compounds / Q000097:blood; D055815:Young Adult
chemical_list: C115436:APLN protein, human; D000975:Antioxidants; D000073861:Apelin; D015415:Biomarkers; D036341:Intercellular Signaling Peptides and Proteins; D013438:Sulfhydryl Compounds; D054409:Nicotinamide Phosphoribosyltransferase
keywords: Apelin; oxidative stress; premenstrual syndrome; visfatin