title: Nanometer-sized manganese oxide-quenched fluorescent oligonucleotides: an effective sensing platform for probing biomolecular interactions.
abstract: We propose a novel template-assisted strategy to prepare nanometer-sized manganese oxide (nano-MnO2) by self-assembly of some MnO2 platelets and demonstrate its application as a new class of biosensing platform for probing DNA hybridization and aptamer-target interaction in a homogeneous solution.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Institute of Biology, Hunan University, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Changsha 410082, China. kmwang@hnu.edu.cn xiaoxiaohe@hnu.edu.cn.
authors.forename: Dinggeng
authors.initials: D
authors.lastname: He
authors.forename: Xiaoxiao
authors.initials: X
authors.lastname: He
authors.forename: Kemin
authors.initials: K
authors.lastname: Wang
authors.forename: Xue
authors.initials: X
authors.lastname: Yang
authors.forename: Xiaoxiao
authors.initials: X
authors.lastname: Yang
authors.forename: Xuecai
authors.initials: X
authors.lastname: Li
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zou
mesh_terms: D052157:Aptamers, Nucleotide / Q000737:chemistry; D015374:Biosensing Techniques; D004247:DNA / Q000032:analysis; D004277:DNA, Single-Stranded / Q000737:chemistry / Q000378:metabolism; D031541:Fluorescence Resonance Energy Transfer; D005456:Fluorescent Dyes / Q000737:chemistry; D017895:Manganese Compounds / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry*; D009693:Nucleic Acid Hybridization; D009841:Oligonucleotides / Q000737:chemistry* / Q000378:metabolism; D010087:Oxides / Q000737:chemistry*; D010316:Particle Size; D055672:Static Electricity; D013501:Surface-Active Agents / Q000737:chemistry
chemical_list: D052157:Aptamers, Nucleotide; D004277:DNA, Single-Stranded; D005456:Fluorescent Dyes; D017895:Manganese Compounds; D009841:Oligonucleotides; D010087:Oxides; D013501:Surface-Active Agents; C027424:manganese oxide; D004247:DNA