title: Primary care management of non-institutionalized elderly diabetic patients: The S.AGES cohort - Baseline data.
abstract: OBJECTIVE
  S.AGES is a multicenter prospective cohort study of non-institutionalized patients aged 65 and over with atrial fibrillation, type 2 diabetes or chronic pain. Its objective is to describe the medical management in primary care. This article presents the baseline characteristics of subjects in the diabetes subcohort and compares the results to those from cohorts of older diabetic patients.
  
  
  METHODS
  From April 2009 to June 2011, 983 patients were included in the diabetes subcohort by 213 primary care providers. Demographic data, geriatric parameters and the history, characteristics and treatment of the diabetes were recorded at baseline.
  
  
  RESULTS
  The mean age was 76.7 ± 5.9 years. Most patients were living independently, with no cognitive impairment and in relatively good health. The duration of diabetes was 11.3 ± 8.7 years with average HbA1c of 6.9 ± 1.0%. 20% of patients had macrovascular disease, 33% renal failure, 14.6% ocular complication and 7.1% neuropathy. The first-line antidiabetic treatment was metformin (61.2%) and 18% of patients had used insulin. Treatment intensified with the worsening of diabetic symptoms. When compared to those from French and North American cohorts, the results showed increased complications and use of insulin with age, disease duration and severity.
  
  
  CONCLUSIONS
  Due to the method of recruitment, S.AGES patients were generally healthy with well-controlled diabetes. However, the results were consistent with those from other cohorts. Three-year follow-up is expected to study the management of diabetic patients aged 65 and over in primary care.
authors.affiliation: General Practice Department, Paris-Sud Faculty of Medicine, University of Paris-Sud, Le Kremlin-Bicêtre, France; INSERM, CESP Centre for Research in Epidemiology and Population Health, U1018, Gender, Sexual and Reproductive Health Team, University of Paris-Sud, Le Kremlin-Bicêtre, France. Electronic address: sophie.bucher@u-psud.fr.
authors.forename: Sophie
authors.initials: S
authors.lastname: Bucher
authors.affiliation: Endocrinology Department, Begin Hospital, Saint Mandé, France.
authors.forename: Bernard
authors.initials: B
authors.lastname: Bauduceau
authors.affiliation: Medical Director of ORPEA/CLINEA, Puteaux, France.
authors.forename: Linda
authors.initials: L
authors.lastname: Benattar-Zibi
authors.affiliation: Rheumatology Department, Limoges University Hospital, Limoges, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Bertin
authors.affiliation: Clinical Gerontology, Nantes University Hospital, France.
authors.forename: Gilles
authors.initials: G
authors.lastname: Berrut
authors.affiliation: INSERM U 669, Paris-Sud Faculty of Medicine, University of Paris-Sud, Psychiatry Department, Bicêtre University Hospital, Assistance Publique-Hôpitaux de Paris, Le Kremlin-Bicêtre, France.
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Corruble
authors.affiliation: HEGP, Coronary Diseases, Paris, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Danchin
authors.affiliation: Pharmacology Department, Paris-Sud Faculty of Medicine, University of Paris-Sud, Assistance Publique-Hôpitaux de Paris, Bicêtre Hospital, Le Kremlin-Bicêtre, France.
authors.forename: Tiba
authors.initials: T
authors.lastname: Delespierre
authors.affiliation: Cardiovascular Functional Exploration, Louis Pradel Hospital, Hospices Civils de Lyon, Bron, France.
authors.forename: Geneviève
authors.initials: G
authors.lastname: Derumeaux
authors.affiliation: Internal Medicine, Geriatry and Therapeutics, Saint Julien University Hospital, Rouen University, Rouen, France.
authors.forename: Jean
authors.initials: J
authors.lastname: Doucet
authors.affiliation: INSERM U 669, Paris-Sud Faculty of Medicine, University of Paris-Sud, Biostatistics Department, Assistance Publique-Hôpitaux de Paris, Paul Brousse Hospital, Le Kremlin-Bicêtre, France.
authors.forename: Bruno
authors.initials: B
authors.lastname: Falissard
authors.affiliation: University of Paris Descartes, National Foundation of Gerontology, Paris, France.
authors.forename: Francoise
authors.initials: F
authors.lastname: Forette
authors.affiliation: University of Paris Descartes, EA 4468, AP-HP, Broca Hospital, Geriatrics Department, Paris, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Hanon
authors.affiliation: General Practice Department, Paris-Sud Faculty of Medicine, University of Paris-Sud, Le Kremlin-Bicêtre, France.
authors.forename: Rissane
authors.initials: R
authors.lastname: Ourabah
authors.affiliation: University of Lille Nord de France, UDSL, EA 1046, CHU, Lille, France.
authors.forename: Florence
authors.initials: F
authors.lastname: Pasquier
authors.affiliation: Pharmacology Department, Paris-Sud Faculty of Medicine, University of Paris-Sud, Assistance Publique-Hôpitaux de Paris, Bicêtre Hospital, Le Kremlin-Bicêtre, France.
authors.forename: Celine
authors.initials: C
authors.lastname: Piedvache
authors.affiliation: Endocrinology, Diabetes and Nutrition-Related Diseases (NUDE Unit), Strasbourg University Hospital and the European Centre for the Study of Diabetes (CeeD), University of Strasbourg, Strasbourg, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Pinget
authors.affiliation: INSERM, CESP Centre for Research in Epidemiology and Population Health, U1018, Gender, Sexual and Reproductive Health Team, University of Paris-Sud, Le Kremlin-Bicêtre, France.
authors.forename: Virginie
authors.initials: V
authors.lastname: Ringa
authors.affiliation: Pharmacology Department, Paris-Sud Faculty of Medicine, University of Paris-Sud, Assistance Publique-Hôpitaux de Paris, Bicêtre Hospital, Le Kremlin-Bicêtre, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Becquemont
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000187:drug effects / Q000378:metabolism; D015897:Comorbidity; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology; D005260:Female; D005602:France / Q000453:epidemiology; D015577:Geriatric Assessment; D006442:Glycated Hemoglobin / Q000378:metabolism; D006299:Health Services for the Aged; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D057187:Independent Living; D008019:Life Style; D008297:Male; D011320:Primary Health Care / Q000379:methods*; D011446:Prospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; C517652:hemoglobin A1c protein, human
keywords: Aged; Pharmacoepidemiology; Primary care; Type 2 diabetes mellitus