title: Continuous objective recording of fetal heart rate and fetal movements could reliably identify fetal compromise, which could reduce stillbirth rates by facilitating timely management.
abstract: Stillbirth currently affects approximately 1 in every 200 pregnancies in the United Kingdom. Fetuses may exhibit signs of compromise as part of a stress response before stillbirth, including reduced fetal movements (RFM) and fetal heart rate (FHR) alterations. At present, and despite widespread use, current fetal monitoring is not associated with a reduction in perinatal mortality rate (PMR) as signs of fetal compromise are not adequately detected. This may be attributed to inaccuracies resulting from manual interpretation of results or subjective assessment of fetal activity. In addition, signs of compromise often occur only hours or days before fetal death, so may be missed by current monitoring methods, which are performed intermittently. A significant consideration is that correct identification of these signs and consequent intervention can result in the delivery of a healthy baby, thus preventing stillbirth. A hypothesis is presented, proposing prompt detection of fetal compromise with the use of 24-hour continuous objective fetal monitoring. With focus placed on obtaining long-term FHR and fetal movement data, prior interest has been found in developing devices for this purpose. However, introduction into clinical practice has not been achieved. Investigation of the hypothesis will begin with the design of a device to record the mentioned parameters, followed by an appropriate validation process. Should development and testing be successful, an eventual comparison in PMR with the use of continuous fetal monitoring vs current monitoring would address the hypothesis. It is suggested that a timely yet reliable indication of fetal wellbeing obtained via long-term monitoring would allow prompt and appropriate obstetric intervention and consequently reduce PMR.
authors.affiliation: Maternal and Fetal Health Research Centre, University of Manchester, St. Mary's Hospital, Oxford Road, Manchester M13 9WL, United Kingdom.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Brown
authors.affiliation: School of Electrical and Electronic Engineering, University of Manchester, Sackville Street Building, Manchester M13 9PL, United Kingdom.
authors.forename: Jayawan H B
authors.initials: JH
authors.lastname: Wijekoon
authors.affiliation: School of Materials, University of Manchester, Oxford Road, M13 9PL, United Kingdom.
authors.forename: Anura
authors.initials: A
authors.lastname: Fernando
authors.affiliation: Maternal and Fetal Health Research Centre, University of Manchester, St. Mary's Hospital, Oxford Road, Manchester M13 9WL, United Kingdom.
authors.forename: Edward D
authors.initials: ED
authors.lastname: Johnstone
authors.affiliation: Maternal and Fetal Health Research Centre, University of Manchester, St. Mary's Hospital, Oxford Road, Manchester M13 9WL, United Kingdom. Electronic address: alex_heazell@talk21.com.
authors.forename: Alexander E P
authors.initials: AE
authors.lastname: Heazell
mesh_terms: D015148:Cardiotocography / Q000379:methods; D019317:Evidence-Based Medicine; D005260:Female; D005313:Fetal Death / Q000517:prevention & control; D005323:Fetal Monitoring / Q000379:methods*; D005324:Fetal Movement / Q000502:physiology*; D006340:Heart Rate, Fetal; D006801:Humans; D009774:Obstetrics / Q000379:methods; D018743:Perinatal Care / Q000379:methods; D011247:Pregnancy; D011295:Prenatal Care / Q000379:methods; D050497:Stillbirth; D016216:Ultrasonography, Prenatal