title: Modern interventional management of stroke.
abstract: Acute ischemic stroke continues to be one of the leading causes of disability and death and is a financial burden to an already taxed health care system. Much research and investigation has been carried out over the past decade on various recanalization devices aimed at restoring cerebral blood flow. Despite the rapidly improving technical abilities of these devices, it has been difficult to demonstrate corresponding improved clinical outcomes. This article will describe the application of the most recent generation of these devices and briefly discuss the ongoing discrepancy between these technical achievements and stroke outcomes.
authors.affiliation: University of Tennessee Medical Center Knoxville, Knoxville, Tennessee.
authors.forename: Andrew S
authors.initials: AS
authors.lastname: Ferrell
authors.affiliation: Houston Methodist Hospital, Houston, Texas.
authors.forename: Y Jonathan
authors.initials: YJ
authors.lastname: Zhang
authors.affiliation: Houston Methodist Hospital, Houston, Texas.
authors.forename: Orlando
authors.initials: O
authors.lastname: Diaz
authors.affiliation: Houston Methodist Hospital, Houston, Texas.
authors.forename: Richard
authors.initials: R
authors.lastname: Klucznik
authors.affiliation: Houston Methodist Hospital, Houston, Texas.
authors.forename: Gavin W
authors.initials: GW
authors.lastname: Britz
mesh_terms: D002545:Brain Ischemia / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D002560:Cerebrovascular Circulation; D057510:Endovascular Procedures / Q000009:adverse effects / Q000379:methods / Q000401:mortality; D005343:Fibrinolytic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D007261:Infusions, Intra-Arterial; D007262:Infusions, Intravenous; D012307:Risk Factors; D020521:Stroke / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D017131:Thrombectomy / Q000009:adverse effects / Q000379:methods / Q000401:mortality; D015912:Thrombolytic Therapy / Q000009:adverse effects / Q000379:methods / Q000401:mortality; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents
keywords: stent retriever; stroke; thrombolysis
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