title: Oncogenic osteomalacia induced by a sinonasal tumour: case report and review.
abstract: BACKGROUND
  Oncogenic osteomalacia (OOM) is a rare paraneoplastic syndrome characterized by hypophosphatemia and overexpression of a phosphaturic agent, fibroblast growth factor 23 (FGF23). OOM is associated with a variety of mesenchymal tumours referred to as phosphaturic mesenchymal tumours. Head and neck regions are concerned in 5-10% of cases.
  
  
  RESULTS
  We report the case of a 42-year-old female with OOM caused by a hemangiopericytoma of the left ethmoid sinus. The period between first symptoms and surgical excision of the lesion was approximately 5 years. We also conducted a PubMed-based search to identify all cases of OOM related to sinonasal tumour. Twenty eight cases in the sinonasal area were reported in the literature.
  
  
  CONCLUSIONS
  OOM is an important diagnosis because resection of the causative tumour results in cure of the disease.
authors.forename: H
authors.initials: H
authors.lastname: Kabtouri
authors.forename: R
authors.initials: R
authors.lastname: Karmali
authors.forename: L
authors.initials: L
authors.lastname: Spinato
authors.forename: M
authors.initials: M
authors.lastname: Khamaktchian
authors.forename: P
authors.initials: P
authors.lastname: Bisschop
mesh_terms: D000328:Adult; D005005:Ethmoid Sinus; D005260:Female; D000089703:Fibroblast Growth Factor-23; D006393:Hemangiopericytoma / Q000150:complications*; D006801:Humans; D009372:Neoplasms, Connective Tissue / Q000209:etiology*; D010018:Osteomalacia; D010255:Paranasal Sinus Neoplasms / Q000150:complications*; D010257:Paraneoplastic Syndromes / Q000150:complications*