title: Synchronous activation within the default mode network correlates with perceived social support.
abstract: Perceived social support emphasizes subjective feeling of provisions offered by family, friends and significant others. In consideration of the great significance of perceived social support to health outcomes, attempt to reveal the neural substrates of perceived social support will facilitate its application in a series of mental disorders. Perceived social support potentially relies on healthy interpersonal relationships calling for cognitive processes like perspective taking, empathy and theory of mind. Interestingly, functional activations and connectivity within the default mode network (DMN) are extensively involved in these interpersonal skills. As a result, it is proposed that synchronous activities among brain regions within the DMN will correlate with self-report of perceived social support. In the present study, we tried to investigate the associations between coherence among the DMN regions and perceived social support at resting state. A total of 333 (145 men) participants were directed to fulfill the Multidimensional Scale of Perceived Social Support (MSPSS) after a 484-s functional magnetic resonance imaging (fMRI) scanning without any task. As a result, seed-based functional connectivity and power spectrum analyses revealed that heightened synchronicity among the DMN regions was associated with better performance on perceived social support. Moreover, results in the present study were independent of different methods, structural changes, and general cognitive performance.
authors.affiliation: Key Laboratory of Cognition and Personality (SWU), Ministry of Education, Chongqing 400715, China; Department of Psychology, Southwest University, Chongqing 400715, China.
authors.forename: Xianwei
authors.initials: X
authors.lastname: Che
authors.affiliation: Key Laboratory of Cognition and Personality (SWU), Ministry of Education, Chongqing 400715, China; Department of Psychology, Southwest University, Chongqing 400715, China. Electronic address: zhangql@swu.edu.cn.
authors.forename: Qinglin
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: College of Mechanical and Electronic Engineering, Northwest A&F University, Shaanxi 712100, China.
authors.forename: Jizheng
authors.initials: J
authors.lastname: Zhao
authors.affiliation: Key Laboratory of Cognition and Personality (SWU), Ministry of Education, Chongqing 400715, China; Department of Psychology, Southwest University, Chongqing 400715, China.
authors.forename: Dongtao
authors.initials: D
authors.lastname: Wei
authors.affiliation: Key Laboratory of Cognition and Personality (SWU), Ministry of Education, Chongqing 400715, China; Department of Psychology, Southwest University, Chongqing 400715, China.
authors.forename: Bingbing
authors.initials: B
authors.lastname: Li
authors.affiliation: Key Laboratory of Cognition and Personality (SWU), Ministry of Education, Chongqing 400715, China; Department of Psychology, Southwest University, Chongqing 400715, China.
authors.forename: Yanan
authors.initials: Y
authors.lastname: Guo
authors.affiliation: Key Laboratory of Cognition and Personality (SWU), Ministry of Education, Chongqing 400715, China; Department of Psychology, Southwest University, Chongqing 400715, China. Electronic address: qiuj318@swu.edu.cn.
authors.forename: Jiang
authors.initials: J
authors.lastname: Qiu
authors.affiliation: Key Laboratory of Cognition and Personality (SWU), Ministry of Education, Chongqing 400715, China; Department of Psychology, Southwest University, Chongqing 400715, China.
authors.forename: Yijun
authors.initials: Y
authors.lastname: Liu
mesh_terms: D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009415:Nerve Net / Q000502:physiology*; D012938:Social Perception; D012944:Social Support
keywords: Default mode network; Perceived social support; Synchronicity