title: Multi-parameter brain tissue microsensor and interface systems: calibration, reliability and user experiences of pressure and temperature sensors in the setting of neurointensive care.
abstract: The objective was to investigate sensor measurement uncertainty for intracerebral probes inserted during neurosurgery and remaining in situ during neurocritical care. This describes a prospective observational study of two sensor types and including performance of the complete sensor-bedside monitoring and readout system. Sensors from 16 patients with severe traumatic brain injury (TBI) were obtained at the time of removal from the brain. When tested, 40% of sensors achieved the manufacturer temperature specification of 0.1 °C. Pressure sensors calibration differed from the manufacturers at all test pressures in 8/20 sensors. The largest pressure measurement error was in the intraparenchymal triple sensor. Measurement uncertainty is not influenced by duration in situ. User experiences reveal problems with sensor 'handling', alarms and firmware. Rigorous investigation of the performance of intracerebral sensors in the laboratory and at the bedside has established measurement uncertainty in the 'real world' setting of neurocritical care.
authors.affiliation: Centre for Health and Social Care Research, Sheffield Hallam University, Montgomery House , 32 Collegiate Crescent , Sheffield S10 2BP .
authors.forename: Charmaine
authors.initials: C
authors.lastname: Childs
authors.forename: Li
authors.initials: L
authors.lastname: Wang
authors.forename: Boon Kwee
authors.initials: BK
authors.lastname: Neoh
authors.forename: Hok Liok
authors.initials: HL
authors.lastname: Goh
authors.forename: Mya Myint
authors.initials: MM
authors.lastname: Zu
authors.forename: Phyo Wai
authors.initials: PW
authors.lastname: Aung
authors.forename: Tseng Tsai
authors.initials: TT
authors.lastname: Yeo
mesh_terms: D001831:Body Temperature; D001921:Brain / Q000502:physiology*; D001930:Brain Injuries / Q000503:physiopathology; D002138:Calibration; D003422:Critical Care; D006801:Humans; D007427:Intracranial Pressure; D008991:Monitoring, Physiologic / Q000295:instrumentation*; D035501:Uncertainty
keywords: Brain; measurement error; neuromonitoring; temperature; uncertainty budget