title: Enhancement of human skin facial revitalization by moringa leaf extract cream.
abstract: BACKGROUND
  Solar ultraviolet exposure is the main cause of skin damage by initiation of reactive oxygen species (ROS) leading to skin collagen imperfection and eventually skin roughness. This can be reduced by proper revitalization of skin enhancing younger and healthier appearance.
  
  
  OBJECTIVE
  To evaluate the skin facial revitalization effect of a cream formulation containing the Moringa oleifera leaf extract on humans.
  
  
  METHODS
  Active cream containing 3% of the concentrated extract of moringa leaves was developed by entrapping in the inner aqueous phase of cream. Base contained no extract. Skin revitalizing parameters, i.e. surface, volume, texture parameters and surface evaluation of the living skin (SELS) were assessed comparatively after application of the base and active cream on human face using Visioscan(®) VC 98 for a period of 3 months.
  
  
  RESULTS
  Surface values were increased by the base and decreased by the active cream. Effects produced for the base and active cream were significant and insignificant, respectively, as observed in the case of surface. Unlike the base, the active cream showed significant effects on skin volume, texture parameters (energy, variance and contrast) and SELS, SEr (skin roughness), SEsc (skin scaliness), SEsm (skin smoothness), and SEw (skin wrinkles) parameters.
  
  
  CONCLUSIONS
  The results suggested that moringa cream enhances skin revitalization effect and supports anti-aging skin effects.
authors.affiliation: Institute of Pharmaceutical Sciences, University of Veterinary and Animal Sciences, Lahore, Pakistan. Head of Institute: Dr. Farzana Chowdhary ; Department of Pharmacy, Faculty of Pharmacy and Alternative Medicine, Islamia University of Bahawalpur, Bahawalpur, Pakistan. Head of Department: Prof. Dr. Naveed Akhtar.
authors.forename: Atif
authors.initials: A
authors.lastname: Ali
authors.affiliation: Department of Pharmacy, Faculty of Pharmacy and Alternative Medicine, Islamia University of Bahawalpur, Bahawalpur, Pakistan. Head of Department: Prof. Dr. Naveed Akhtar.
authors.forename: Naveed
authors.initials: N
authors.lastname: Akhtar
authors.affiliation: Institute of Pharmaceutical Sciences, University of Veterinary and Animal Sciences, Lahore, Pakistan. Head of Institute: Dr. Farzana Chowdhary.
authors.forename: Farzana
authors.initials: F
authors.lastname: Chowdhary
keywords: Moringa oleifera; cream; facial revitalization
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