title: Techniques of autologous pericardial leaflet replacement for aortic valve reconstruction.
abstract: Glutaraldehyde-fixed autologous pericardium rarely calcifies or retracts, and it is a useful substitute for cardiac valve leaflets. Current understanding of aortic valve geometry provides good models for aortic leaflet design, and pericardial leaflet construction is illustrated in this article for bicuspid and tri-leaflet valves. Outcomes have been characterized by low valve-related complication rates, and results of recent series are encouraging. Perhaps sufficient data are available to consider autologous pericardial leaflet replacement in highly selected younger patients with irreparable leaflets and contraindications to warfarin.
authors.affiliation: Vanderbilt University, Nashville, Tennessee. Electronic address: jsrankinmd@cs.com.
authors.forename: J Scott
authors.initials: JS
authors.lastname: Rankin
authors.affiliation: Technische Universität München, Deutsches Herzzentrum München, Munich, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Nöbauer
authors.affiliation: Vanderbilt University, Nashville, Tennessee.
authors.forename: Philip S
authors.initials: PS
authors.lastname: Crooke
authors.affiliation: Technische Universität München, Deutsches Herzzentrum München, Munich, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Schreiber
authors.affiliation: Technische Universität München, Deutsches Herzzentrum München, Munich, Germany.
authors.forename: Rüdiger
authors.initials: R
authors.lastname: Lange
authors.affiliation: Technische Universität München, Deutsches Herzzentrum München, Munich, Germany.
authors.forename: Domenico
authors.initials: D
authors.lastname: Mazzitelli
mesh_terms: D001021:Aortic Valve / Q000601:surgery*; D001705:Bioprosthesis; D006348:Cardiac Surgical Procedures / Q000379:methods; D005976:Glutaral; D006801:Humans; D010496:Pericardium / Q000637:transplantation*; D011474:Prosthesis Design; D014182:Transplantation, Autologous
chemical_list: D005976:Glutaral