title: Functional and metabolic changes in the brain in neuropathic pain syndrome against the background of chronic epidural electrostimulation of the spinal cord.
abstract: Changes in functional and metabolic activities of the brain were evaluated by EEG and positron-emission/computer tomography with 18F-fluorodeoxyglucose in patients with neuropathic pain syndrome previous to and 3 months after implantation of a system for chronic epidural spinal cord stimulation. In most cases, the use of a nerve stimulator was followed by alleviation of neuropathic pain and partial normalization of functional and metabolic activities of brain structures responsible for pain perception, emotiogenic, behavioral, and autonomic responses.
authors.affiliation: Federal Center of Neurosurgery, Ministry of Health of the Russian Federation, Tyumen, Russia, sufianov@mail.ru.
authors.forename: A A
authors.initials: AA
authors.lastname: Sufianov
authors.forename: A G
authors.initials: AG
authors.lastname: Shapkin
authors.forename: G Z
authors.initials: GZ
authors.lastname: Sufianova
authors.forename: V G
authors.initials: VG
authors.lastname: Elishev
authors.forename: D A
authors.initials: DA
authors.lastname: Barashin
authors.forename: V B
authors.initials: VB
authors.lastname: Berdichevskii
authors.forename: S V
authors.initials: SV
authors.lastname: Churkin
mesh_terms: D000328:Adult; D001921:Brain / Q000378:metabolism / Q000503:physiopathology*; D016022:Case-Control Studies; D004569:Electroencephalography; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism; D006801:Humans; D058542:Implantable Neurostimulators; D008297:Male; D008875:Middle Aged; D009437:Neuralgia / Q000378:metabolism / Q000503:physiopathology / Q000601:surgery / Q000628:therapy*; D059225:Nociception; D059408:Pain Management / Q000379:methods*; D049268:Positron-Emission Tomography; D013116:Spinal Cord / Q000503:physiopathology / Q000601:surgery; D062187:Spinal Cord Stimulation / Q000295:instrumentation / Q000379:methods*
chemical_list: D019788:Fluorodeoxyglucose F18