title: Severe anemia in an adolescent male with sickle cell trait: a case report.
abstract: BACKGROUND
  Sickle cell trait is generally considered a benign condition. However, it has been associated with uncommon comorbidities such as painless gross hematuria secondary to renal papillary necrosis and renal medullary carcinoma.
  
  
  METHODS
  We present a 16-year-old African American boy with sickle cell trait and a recent history of prolonged gross hematuria due to renal papillary necrosis. The patient developed severe iron deficiency anemia and required transfusion support.
  
  
  CONCLUSIONS
  Although renal papillary necrosis is well-described, it is uncommon in pediatrics and only rarely results in the need for transfusion.
authors.affiliation: Division of Pediatric Hematology/Oncology, Department of Pediatrics, John H. Stroger Jr. Hospital of Cook County, Chicago, IL.
authors.forename: Adrian
authors.initials: A
authors.lastname: Chapa-Rodriguez
authors.forename: Dipti
authors.initials: D
authors.lastname: Dighe
authors.forename: Lisa
authors.initials: L
authors.lastname: Giordano
mesh_terms: D000293:Adolescent; D018798:Anemia, Iron-Deficiency / Q000209:etiology*; D006417:Hematuria / Q000209:etiology; D006801:Humans; D007681:Kidney Papillary Necrosis / Q000150:complications; D008297:Male; D012805:Sickle Cell Trait / Q000150:complications*