title: Copper(I) bromide catalyzed arylation of cyclic enamides and naphthyl-1-acetamides using diaryliodonium salts.
abstract: Copper(I) bromide catalyzed direct C-H arylation of cyclic enamides was achieved using diaryliodonium salts in the absence of base/additive at ambient temperature with high yields. A biologically active dihydro[a]benzocarbazole scaffold was synthesized using the established protocol. The scope of the current methodology was further extended for the synthesis of C4-, C7-aryl-substituted 1-naphthyl acetamides in good yields.
authors.affiliation: Chemical Biology Lab, Department of Biotechnology, Bhupat and Jyothi Mehta School of Biosciences Building, Indian Institute of Technology Madras , Chennai-600036, India.
authors.forename: Muthuraj
authors.initials: M
authors.lastname: Prakash
authors.forename: Subramaniam
authors.initials: S
authors.lastname: Muthusamy
authors.forename: Venkitasamy
authors.initials: V
authors.lastname: Kesavan
mesh_terms: D000081:Acetamides / Q000138:chemical synthesis* / Q000737:chemistry; D002227:Carbazoles / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D015394:Molecular Structure; D012492:Salts / Q000737:chemistry
chemical_list: D000081:Acetamides; D002227:Carbazoles; D012492:Salts; D003300:Copper