title: Three New Humulane Sesquiterpenes from Cultures of the Fungus Antrodiella albocinnamomea.
abstract: Three new humulane-type sesquiterpenes, antrodols A-C (1-3), were isolated from cultures of the fungus Antrodiella albocinnamomea. Their structures were elucidated on the basis of extensive spectroscopic analysis. Antrodols A-C (1-3) are first examples of humulane-type sesquiterpenes isolated from cultures of higher fungi, and antrodol A (1) was the first report of humulane-type sesquiterpene with a methyl rearranged at C-3. All compounds were evaluated in the enzyme inhibition assay against two protein-tyrosine phosphatases (PTPs): MEG2 and PTP1Bc.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 132# Lanhei Road, Heilongtan, Kunming, 650201 Yunnan People's Republic of China.
authors.forename: Zi-Ming
authors.initials: ZM
authors.lastname: Chen
authors.affiliation: College of Life Science, Hebei Normal University, Shijiazhuang, 050024 People's Republic of China.
authors.forename: Qiong-Ying
authors.initials: QY
authors.lastname: Fan
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 132# Lanhei Road, Heilongtan, Kunming, 650201 Yunnan People's Republic of China.
authors.forename: Xia
authors.initials: X
authors.lastname: Yin
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 132# Lanhei Road, Heilongtan, Kunming, 650201 Yunnan People's Republic of China.
authors.forename: Xiao-Yan
authors.initials: XY
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 132# Lanhei Road, Heilongtan, Kunming, 650201 Yunnan People's Republic of China.
authors.forename: Zheng-Hui
authors.initials: ZH
authors.lastname: Li
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 132# Lanhei Road, Heilongtan, Kunming, 650201 Yunnan People's Republic of China.
authors.forename: Tao
authors.initials: T
authors.lastname: Feng
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 132# Lanhei Road, Heilongtan, Kunming, 650201 Yunnan People's Republic of China.
authors.forename: Ji-Kai
authors.initials: JK
authors.lastname: Liu
keywords: Antrodiella albocinnamomea; Humulane-type sesquiterpenes; Protein tyrosine phosphatase inhibitory activity
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