title: Highly enantioselective [3+2] coupling of indoles with quinone monoimines promoted by a chiral phosphoric acid.
abstract: Highly enantioselective [3+2] coupling of 3-substituted indoles with quinone monoimines promoted by a chiral phosphoric acid has been reported. A large variety of benzofuroindolines were prepared in moderate to good yields (up to 98%) with generally excellent enantioselectivities (up to 99% ee).
authors.affiliation: Key Laboratory for Asymmetric Synthesis and Chiral Technology of Sichuan Province, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu, 610041 (China); University of Chinese Academy of Sciences, Beijing, 100049 (China).
authors.forename: Lihua
authors.initials: L
authors.lastname: Liao
authors.forename: Chang
authors.initials: C
authors.lastname: Shu
authors.forename: Minmin
authors.initials: M
authors.lastname: Zhang
authors.forename: Yijun
authors.initials: Y
authors.lastname: Liao
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Hu
authors.forename: Yonghong
authors.initials: Y
authors.lastname: Zhang
authors.forename: Zhijun
authors.initials: Z
authors.lastname: Wu
authors.forename: Weicheng
authors.initials: W
authors.lastname: Yuan
authors.forename: Xiaomei
authors.initials: X
authors.lastname: Zhang
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D061565:Cycloaddition Reaction; D007097:Imines / Q000138:chemical synthesis / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D008968:Molecular Conformation; D010756:Phosphoric Acids / Q000737:chemistry*; D011809:Quinones / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007097:Imines; D007211:Indoles; D010756:Phosphoric Acids; D011809:Quinones; C030242:phosphoric acid
keywords: asymmetric catalysis; enantioselectivity; heterocycles; indoles; organocatalysis