title: [Hypercalcaemia can be the only initial symptom of sarcoidosis].
abstract: Sarcoidosis is an ordinary systemic inflammatory disease that can affect many organs. It is characterized by development of non-necrotizing granulomas. It commonly affects lungs (80%) while hypercalcaemia is found in 5% and reflects an activation of T-cells within the granulomas that causes an overproduction of 1,25-dihydroxyvitamin D3. We describe a case where hypercalcaemia was the only symptom in a patient with extrapulmonary sarcoidosis, and the investigation was misled by different serologic findings though PET-CT showed fludeoxyglucose uptake in the biceps femoris muscles. The diagnosis was made after a biopsy.
authors.affiliation: Amerikavej 6, 4. th., 1756 København V. thermanrud@gmail.com.
authors.forename: Thorbjørn
authors.initials: T
authors.lastname: Hermanrud
authors.forename: Julie Hjortsø
authors.initials: JH
authors.lastname: Janner
authors.forename: Ida Elisabeth
authors.initials: IE
authors.lastname: Steffensen
mesh_terms: D000368:Aged; D005938:Glucocorticoids / Q000627:therapeutic use; D006099:Granuloma / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D008297:Male; D018482:Muscle, Skeletal / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use; D012507:Sarcoidosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone