title: Incidence and risk factors for AIDS-related mortality in HIV patients in China: a cross-sectional study.
abstract: BACKGROUND
  To estimate the incidence and risk factors for mortality in HIV-1-infected patients in China.
  
  
  METHODS
  Information on AIDS-related deaths was collected from the Chinese Center for Disease Control and Prevention's Disease Surveillance Information Reporting System and AIDS Prevention and Control Information System.
  
  
  RESULTS
  A total of 379,348 HIV cases were recorded in the databases from 2006. Among those, 138,288 patients were reported as having developed AIDS and 72,616 (19%) died of AIDS after data was extracted from the databases in January 2011. Mortality was higher among those patients aged 50 years old or older (AOR: 3.41, CI: 1.47-7.91) who had been infected by intravenous drug use (AOR: 1.65, CI: 1.28-2.14) or blood transfusion/donation (AOR: 2.18: 1.18-3.99). Compared to patients who had not initiated highly active antiretroviral therapy (HAART), those who had initiated HAART were more likely to have a long interval of time between infection confirmation and AIDS-related death.
  
  
  CONCLUSIONS
  The effective reduction of AIDS mortality could be improved through timely treatment.
authors.forename: Hui
authors.initials: H
authors.lastname: Zheng
authors.forename: Lu
authors.initials: L
authors.lastname: Wang
authors.forename: Peng
authors.initials: P
authors.lastname: Huang
authors.forename: Jessie
authors.initials: J
authors.lastname: Norris
authors.forename: Qing
authors.initials: Q
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Guo
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, China. zhihangpeng@njmu.edu.cn.
authors.forename: Zhihang
authors.initials: Z
authors.lastname: Peng
authors.forename: Rongbin
authors.initials: R
authors.lastname: Yu
authors.forename: Ning
authors.initials: N
authors.lastname: Wang
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy / Q000209:etiology / Q000401:mortality* / Q000821:virology; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D001782:Blood Donors; D001803:Blood Transfusion; D002487:Centers for Disease Control and Prevention, U.S.; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000209:etiology / Q000401:mortality / Q000821:virology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D015819:Substance Abuse, Intravenous / Q000150:complications; D014481:United States; D055815:Young Adult
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