title: Titanium prosthesis or autologous incus for total ossicular reconstruction in the absence of the stapes suprastructure and presence of mobile footplate.
abstract: The purpose of this study was to compare the hearing results after total ossicular replacement with a titanium prosthesis or autologous incus in the absence of stapes suprastructure and presence of mobile footplate as a retrospective medical record review in a tertiary referral center setting. There were 49 patients who had total ossicular reconstruction (titanium prosthesis, 40 patients; autologous incus, 9 patients). Medical records were reviewed after total ossicular replacement. Air-bone gap at 1 and 2 years after surgery were determined with the 4-frequency average (0.5, 1, 2, and 4 kHz) and the American Academy of Otolaryngology-Head and Neck Surgery 4-frequency average (0.5, 1, 2, and 3 kHz). The number of patients who had air-bone gap <20 dB was determined. For comparisons that were based on American Academy of Otolaryngology-Head and Neck Surgery 4-frequency average, mean air-bone gap at 2 years after surgery was significantly smaller for the titanium prosthesis (21 dB) than autologous incus group (31 dB; P ≤ 0.03); the frequency of patients who had air-bone gap <20 dB at 1 or 2 years after surgery was significantly greater for the titanium prosthesis (1 year, 40%; 2 years, 56%) than autologous incus group [1 year, 0% (P ≤ 0.03); 2 years, 0% (P ≤ 0.04)]. Titanium prosthesis ossiculoplasty gave better results than autologous incus in the absence of the stapes suprastructure and presence of a mobile footplate.
authors.affiliation: Service of Otolaryngology, University Hospital of Rouen, 1 rue germont, 76000, Rouen, France, zakzouk.abdulmajeed@gmail.com.
authors.forename: Abdulmajeed
authors.initials: A
authors.lastname: Zakzouk
authors.forename: Nicolas
authors.initials: N
authors.lastname: Bonmardion
authors.forename: Pierre
authors.initials: P
authors.lastname: Bouchetemble
authors.forename: Yannick
authors.initials: Y
authors.lastname: Lerosey
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Marie
mesh_terms: D000328:Adult; D004432:Ear, Middle / Q000601:surgery; D005260:Female; D006309:Hearing / Q000502:physiology*; D034381:Hearing Loss / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007188:Incus / Q000637:transplantation*; D008297:Male; D009998:Ossicular Prosthesis; D011474:Prosthesis Design; D012189:Retrospective Studies; D013201:Stapes Surgery / Q000379:methods*; D014025:Titanium; D014182:Transplantation, Autologous; D055815:Young Adult
chemical_list: D014025:Titanium
references.citation: Otolaryngol Head Neck Surg. 2001 Sep;125(3):135-41
references.pmid: 11555743
references.citation: Otol Neurotol. 2003 Mar;24(2):149-52
references.pmid: 12621325
references.citation: Otol Neurotol. 2010 Apr;31(3):409-14
references.pmid: 20042992
references.citation: Ear Nose Throat J. 2005 Mar;84(3):142-4, 147-9
references.pmid: 15871581
references.citation: Otol Neurotol. 2010 Jul;31(5):752-8
references.pmid: 20502377
references.citation: Laryngoscope. 2004 Jan;114(1):65-70
references.pmid: 14709997
references.citation: Otolaryngol Head Neck Surg. 2012 Jul;147(1):102-4
references.pmid: 22301102
references.citation: Acta Otolaryngol. 2010 May;130(5):554-8
references.pmid: 19958249
references.citation: Otolaryngol Clin North Am. 1994 Aug;27(4):717-26
references.pmid: 7984371
references.citation: Otol Neurotol. 2012 Jun;33(4):580-5
references.pmid: 22429941
references.citation: Otolaryngol Head Neck Surg. 1995 Sep;113(3):186-7
references.pmid: 7675477
references.citation: Rev Laryngol Otol Rhinol (Bord). 2005;126(1):19-23
references.pmid: 16080643
references.citation: Am J Otol. 1998 Sep;19(5):569-73
references.pmid: 9752962