title: A case report of HCC cutaneous metastasis.
abstract: BACKGROUND
  Hepatocellular carcinoma (HCC) is one of the most common solid tumors in the world. HCC muscle and cutaneous metastases are rare and can occur by hematogenous spread or following surgical procedures performed for diagnostic or therapeutic aims.
  
  
  METHODS
  We present a 47-year-old man underwent liver biopsy followed by surgical resection for moderately differentiated HCC in January 1999. In February 2010 the patient presented with HCC cutaneous metastases in the surgical scare and with HCC metastases of the right abdominal rectus muscle. En bloc tumor resection with the right abdominal rectus muscle was performed. In March 2011 the patient underwent resection of a locoregional muscle relapse. In November 2011 we started Sorafenib for intraepatic recurrence.
  
  
  CONCLUSIONS
  This case suggests that in the follow-up of patients who underwent surgical resection or diagnostic and therapeutic procedures for HCC should be considered the possibility of abdominal wall metastasis even after many years, particularly in the cases with favorable evolution.
authors.affiliation: 1 Medical Oncology, "F. Veneziale" Hospital, Isernia, Italy ; 2 Anatomic Phatology Unit, "F. Veneziale" Hospital, Isernia, Department of Biomorphological Science, Anatomic Pathology Section, Federico II University, Napoli, Italy ; 3 General Surgery, "F. Veneziale" Hospital, Isernia, Italy.
authors.forename: Divina
authors.initials: D
authors.lastname: Traficante
authors.affiliation: 1 Medical Oncology, "F. Veneziale" Hospital, Isernia, Italy ; 2 Anatomic Phatology Unit, "F. Veneziale" Hospital, Isernia, Department of Biomorphological Science, Anatomic Pathology Section, Federico II University, Napoli, Italy ; 3 General Surgery, "F. Veneziale" Hospital, Isernia, Italy.
authors.forename: Pasquale
authors.initials: P
authors.lastname: Assalone
authors.affiliation: 1 Medical Oncology, "F. Veneziale" Hospital, Isernia, Italy ; 2 Anatomic Phatology Unit, "F. Veneziale" Hospital, Isernia, Department of Biomorphological Science, Anatomic Pathology Section, Federico II University, Napoli, Italy ; 3 General Surgery, "F. Veneziale" Hospital, Isernia, Italy.
authors.forename: Federica
authors.initials: F
authors.lastname: Tomei
authors.affiliation: 1 Medical Oncology, "F. Veneziale" Hospital, Isernia, Italy ; 2 Anatomic Phatology Unit, "F. Veneziale" Hospital, Isernia, Department of Biomorphological Science, Anatomic Pathology Section, Federico II University, Napoli, Italy ; 3 General Surgery, "F. Veneziale" Hospital, Isernia, Italy.
authors.forename: Franco
authors.initials: F
authors.lastname: Calista
authors.affiliation: 1 Medical Oncology, "F. Veneziale" Hospital, Isernia, Italy ; 2 Anatomic Phatology Unit, "F. Veneziale" Hospital, Isernia, Department of Biomorphological Science, Anatomic Pathology Section, Federico II University, Napoli, Italy ; 3 General Surgery, "F. Veneziale" Hospital, Isernia, Italy.
authors.forename: Jessica
authors.initials: J
authors.lastname: Falleti
authors.affiliation: 1 Medical Oncology, "F. Veneziale" Hospital, Isernia, Italy ; 2 Anatomic Phatology Unit, "F. Veneziale" Hospital, Isernia, Department of Biomorphological Science, Anatomic Pathology Section, Federico II University, Napoli, Italy ; 3 General Surgery, "F. Veneziale" Hospital, Isernia, Italy.
authors.forename: Enrico
authors.initials: E
authors.lastname: Caranci
authors.affiliation: 1 Medical Oncology, "F. Veneziale" Hospital, Isernia, Italy ; 2 Anatomic Phatology Unit, "F. Veneziale" Hospital, Isernia, Department of Biomorphological Science, Anatomic Pathology Section, Federico II University, Napoli, Italy ; 3 General Surgery, "F. Veneziale" Hospital, Isernia, Italy.
authors.forename: Liberato
authors.initials: L
authors.lastname: Di Lullo
keywords: Hepatocellular carcinoma (HCC); cutaneous metastases; muscle metastases; seeding
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