title: [Dynamics of indices of sympatho-adrenal system at application of a combined central sedation using alpha2a-NMDA and phentanyl].
abstract: The investigation objective was studying of impact of a combined central sedation, using alpha2a-receptors N-methyl-D-aspartate (alpha2a-NMDA) and phentanyl, on dynamics of the sympatho-adrenal system indices. Positive protection of the pain impulses while usage of a standard anesthesia method was established, application of combined central alpha2a-NMDA sedation, using phentanyl, have guaranteed more effective protective action of anesthesia. The standard anesthesia did not guarantee a blocade while application of central alpha2a-NMDA sedation provides inhibition of all types of the receptors, causing subsequent blocade of the tissue basophils.
authors.forename: Ie V
authors.initials: IeV
authors.lastname: Podrez
mesh_terms: D000768:Anesthesia, General / Q000379:methods*; D018686:Anesthetics, Intravenous / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000097:blood / Q000601:surgery; D004837:Epinephrine / Q000097:blood; D005260:Female; D005283:Fentanyl / Q000627:therapeutic use*; D006801:Humans; D010146:Pain / Q000097:blood / Q000517:prevention & control*; D010913:Pituitary-Adrenal System / Q000187:drug effects; D016194:Receptors, N-Methyl-D-Aspartate / Q000037:antagonists & inhibitors* / Q000378:metabolism; D013564:Sympathetic Nervous System / Q000187:drug effects
chemical_list: D018686:Anesthetics, Intravenous; D004837:Epinephrine; D005283:Fentanyl; D016194:Receptors, N-Methyl-D-Aspartate