title: Affective prosody perception in symptomatically remitted patients with schizophrenia and bipolar disorder.
abstract: Affect perception has frequently been shown to be impaired in patients suffering from schizophrenia or bipolar disorder (BD), but it remains unclear whether these impairments exist during symptomatic remission and whether the two disorders differ from each other in this regard. Most previous studies have investigated facial affect recognition, but not the ability to decode mental states from emotional tone of voice, i.e. affective prosody perception (APP). Accordingly, the present study directly compared APP in symptomatically remitted patients with schizophrenia or BD and healthy control subjects and investigated its relationship with residual symptomatology in patients. Patients with schizophrenia and BD showed comparable APP impairments despite being symptomatically remitted. In comparison to healthy control subjects, overall APP deficits were found in BD but not in schizophrenia patients. Both patient groups were particularly impaired in the identification of anger and confounded it with neutral prosody. In addition, schizophrenia patients frequently confused sadness with happiness, anger, or fright. There was an inverse association between the degree of residual positive symptoms and the ability to correctly recognize happiness in schizophrenia patients. Overall, these data indicate that impairments in APP represent an enduring deficit and a trait marker of both schizophrenia and BD and that the level of impairment is comparable between disorders.
authors.affiliation: Innsbruck Medical University, Department of Psychiatry and Psychotherapy, General and Social Psychiatry Division, Anichstrasse 35, 6020 Innsbruck, Austria.
authors.forename: Christine M
authors.initials: CM
authors.lastname: Hoertnagl
authors.affiliation: Innsbruck Medical University, Department of Psychiatry and Psychotherapy, Biological Psychiatry Division, Anichstrasse 35, 6020 Innsbruck, Austria.
authors.forename: Nursen
authors.initials: N
authors.lastname: Yalcin-Siedentopf
authors.affiliation: Innsbruck Medical University, Department of Psychiatry and Psychotherapy, Biological Psychiatry Division, Anichstrasse 35, 6020 Innsbruck, Austria.
authors.forename: Susanne
authors.initials: S
authors.lastname: Baumgartner
authors.affiliation: Innsbruck Medical University, Department of Psychiatry and Psychotherapy, Biological Psychiatry Division, Anichstrasse 35, 6020 Innsbruck, Austria.
authors.forename: Falko
authors.initials: F
authors.lastname: Biedermann
authors.affiliation: Innsbruck Medical University, Department of Psychiatry and Psychotherapy, General and Social Psychiatry Division, Anichstrasse 35, 6020 Innsbruck, Austria.
authors.forename: Eberhard A
authors.initials: EA
authors.lastname: Deisenhammer
authors.affiliation: Innsbruck Medical University, Department of Psychiatry and Psychotherapy, General and Social Psychiatry Division, Anichstrasse 35, 6020 Innsbruck, Austria.
authors.forename: Armand
authors.initials: A
authors.lastname: Hausmann
authors.affiliation: Innsbruck Medical University, Department of Psychiatry and Psychotherapy, Biological Psychiatry Division, Anichstrasse 35, 6020 Innsbruck, Austria.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Kaufmann
authors.affiliation: Innsbruck Medical University, Department of Psychiatry and Psychotherapy, General and Social Psychiatry Division, Anichstrasse 35, 6020 Innsbruck, Austria.
authors.forename: Georg
authors.initials: G
authors.lastname: Kemmler
authors.affiliation: Private Medical University of Salzburg, Department of Psychiatry and Psychotherapy, Ignaz Harrerstrasse 79, 5020 Salzburg, Austria.
authors.forename: Moritz
authors.initials: M
authors.lastname: Mühlbacher
authors.affiliation: Innsbruck Medical University, Department of Psychiatry and Psychotherapy, Biological Psychiatry Division, Anichstrasse 35, 6020 Innsbruck, Austria.
authors.forename: Anna-Sophia
authors.initials: AS
authors.lastname: Rauch
authors.affiliation: Innsbruck Medical University, Department of Psychiatry and Psychotherapy, General and Social Psychiatry Division, Anichstrasse 35, 6020 Innsbruck, Austria; Innsbruck Medical University, Department of Psychiatry and Psychotherapy, Biological Psychiatry Division, Anichstrasse 35, 6020 Innsbruck, Austria.
authors.forename: Wolfgang W
authors.initials: WW
authors.lastname: Fleischhacker
authors.affiliation: Innsbruck Medical University, Department of Psychiatry and Psychotherapy, Biological Psychiatry Division, Anichstrasse 35, 6020 Innsbruck, Austria. Electronic address: a.hofer@i-med.ac.at.
authors.forename: Alex
authors.initials: A
authors.lastname: Hofer
mesh_terms: D000293:Adolescent; D000328:Adult; D001714:Bipolar Disorder / Q000523:psychology*; D003430:Cross-Sectional Studies; D004644:Emotions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011581:Psychological Tests; D012565:Schizophrenic Psychology; D012938:Social Perception; D013067:Speech Perception; D055815:Young Adult
keywords: Affective prosody perception; Bipolar disorder; Schizophrenia; Social cognition