title: Calysolins X-XIII, resin glycosides from Calystegia soldanella, and their antiviral activity toward herpes simplex virus.
abstract: Four new resin glycosides having macrolactone structures (jalapins), named calysolins X (1)-XIII (4), were isolated from the leaves, stems, and roots of Calystegia soldanella ROEM. et SCHULT. (Convolvulaceae). Their structures were determined on the basis of spectroscopic data as well as chemical evidence. The sugar moieties of 1-4 were partially acylated by some organic acids, including tiglic acid, 2S-methylbutyric acid, and 2S,3S-nilic acid. Additionally, the antiviral activity of 1-4 toward herpes simplex virus type 1 was evaluated. All the compounds showed antiviral activity.
authors.affiliation: School of Agriculture, Tokai University.
authors.forename: Masateru
authors.initials: M
authors.lastname: Ono
authors.forename: Gen
authors.initials: G
authors.lastname: Kawakami
authors.forename: Ayako
authors.initials: A
authors.lastname: Takigawa
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Kabata
authors.forename: Masafumi
authors.initials: M
authors.lastname: Okawa
authors.forename: Junei
authors.initials: J
authors.lastname: Kinjo
authors.forename: Kazumi
authors.initials: K
authors.lastname: Yokomizo
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Yoshimitsu
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Nohara
mesh_terms: D000998:Antiviral Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D031253:Calystegia / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D006561:Herpes Simplex / Q000188:drug therapy; D018259:Herpesvirus 1, Human / Q000187:drug effects*; D006801:Humans; D007783:Lactones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D012116:Resins, Plant / Q000737:chemistry*
chemical_list: D000998:Antiviral Agents; D006027:Glycosides; D007783:Lactones; D012116:Resins, Plant