title: Nociceptive neurons regulate innate and adaptive immunity and neuropathic pain through MyD88 adapter.
authors.affiliation: Departments of Anesthesiology and Neurobiology, Duke University Medical Center, Durham, NC 27710.
authors.forename: Xing-Jun
authors.initials: XJ
authors.lastname: Liu
authors.affiliation: 1] Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA [2] State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Peking Union Medical College; Chinese Academy of Medical Sciences, Beijing 100005, China.
authors.forename: Yanli
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: 1] Departments of Anesthesiology and Neurobiology, Duke University Medical Center, Durham, NC 27710 [2] Current address: Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases, Institute of Neuroscience, Soochow University, Suzhou, Jiangsu 215006, China.
authors.forename: Tong
authors.initials: T
authors.lastname: Liu
authors.affiliation: Departments of Anesthesiology and Neurobiology, Duke University Medical Center, Durham, NC 27710.
authors.forename: Zhen-Zhong
authors.initials: ZZ
authors.lastname: Xu
authors.affiliation: Departments of Anesthesiology and Neurobiology, Duke University Medical Center, Durham, NC 27710.
authors.forename: Chul-Kyu
authors.initials: CK
authors.lastname: Park
authors.affiliation: Departments of Anesthesiology and Neurobiology, Duke University Medical Center, Durham, NC 27710.
authors.forename: Temugin
authors.initials: T
authors.lastname: Berta
authors.affiliation: Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
authors.forename: Dianhua
authors.initials: D
authors.lastname: Jiang
authors.affiliation: Departments of Anesthesiology and Neurobiology, Duke University Medical Center, Durham, NC 27710.
authors.forename: Ru-Rong
authors.initials: RR
authors.lastname: Ji
mesh_terms: D056704:Adaptive Immunity / Q000187:drug effects; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology; D039481:CD11b Antigen / Q000378:metabolism; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology / Q000378:metabolism; D005727:Ganglia, Spinal / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D007113:Immunity, Innate / Q000187:drug effects; D007694:Killer Cells, Natural / Q000187:drug effects / Q000276:immunology / Q000378:metabolism; D017493:Leukocyte Common Antigens / Q000378:metabolism; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D053594:Myeloid Differentiation Factor 88 / Q000235:genetics / Q000378:metabolism*; D009437:Neuralgia / Q000378:metabolism / Q000473:pathology*; D009619:Nociceptors / Q000378:metabolism*; D017239:Paclitaxel / Q000494:pharmacology; D050378:T-Lymphocytes, Regulatory / Q000187:drug effects / Q000276:immunology / Q000378:metabolism; D018417:Th1 Cells / Q000187:drug effects / Q000276:immunology / Q000378:metabolism; D018418:Th2 Cells / Q000187:drug effects / Q000276:immunology / Q000378:metabolism
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D039481:CD11b Antigen; D053594:Myeloid Differentiation Factor 88; D017493:Leukocyte Common Antigens; D017239:Paclitaxel
references.citation: Eur J Pain. 2013 Jan;17(1):75-85
references.pmid: 22623135
references.citation: Nat Rev Immunol. 2006 Apr;6(4):318-28
references.pmid: 16557263
references.citation: Pain. 2012 Oct;153(10):2017-2030
references.pmid: 22703890
references.citation: Neurosci Bull. 2012 Apr;28(2):131-44
references.pmid: 22466124
references.citation: Nat Neurosci. 2010 Dec;13(12):1460-2
references.pmid: 21037581
references.citation: Neuron. 2014 Apr 2;82(1):47-54
references.pmid: 24698267
references.citation: Eur J Pharmacol. 2012 Jan 5;674(1):51-7
references.pmid: 22051147
references.citation: Nature. 2013 Sep 5;501(7465):52-7
references.pmid: 23965627
references.citation: Glia. 2011 Feb;59(2):231-41
references.pmid: 21125644
references.citation: Nat Rev Drug Discov. 2014 Jul;13(7):533-48
references.pmid: 24948120
references.citation: Nat Neurosci. 2012 Jul 26;15(8):1063-7
references.pmid: 22837035
references.citation: J Neurosci. 2009 Nov 18;29(46):14415-22
references.pmid: 19923276
references.citation: J Clin Invest. 2012 Jun;122(6):2195-207
references.pmid: 22565312
references.citation: Nature. 2014 Jun 5;510(7503):157-61
references.pmid: 24759321
references.citation: J Pain. 2014 Jul;15(7):712-25
references.pmid: 24755282