title: Modulation of arm reaching movements during processing of arm/hand-related action verbs with and without emotional connotation.
abstract: The theory of embodied language states that language comprehension relies on an internal reenactment of the sensorimotor experience associated with the processed word or sentence. Most evidence in support of this hypothesis had been collected using linguistic material without any emotional connotation. For instance, it had been shown that processing of arm-related verbs, but not of those leg-related verbs, affects the planning and execution of reaching movements; however, at present it is unknown whether this effect is further modulated by verbs evoking an emotional experience. Showing such a modulation might shed light on a very debated issue, i.e. the way in which the emotional meaning of a word is processed. To this end, we assessed whether processing arm/hand-related verbs describing actions with negative connotations (e.g. to stab) affects reaching movements differently from arm/hand-related verbs describing actions with neutral connotation (e.g. to comb). We exploited a go/no-go paradigm in which healthy participants were required to perform arm-reaching movements toward a target when verbs expressing emotional hand actions, neutral hand actions or foot actions were shown, and to refrain from moving when no-effector-related verbs were presented. Reaction times and percentages of errors increased when the verb involved the same effector as used to give the response. However, we also found that the size of this interference decreased when the arm/hand-related verbs had a negative emotional connotation. Crucially, we show that such modulation only occurred when the verb semantics had to be retrieved. These results suggest that the comprehension of negatively valenced verbs might require the simultaneous reenactment of the neural circuitry associated with the processing of the emotion evoked by their meaning and of the neural circuitry associated with their motor features.
authors.affiliation: PhD Program in Neurophysiology, Department of Physiology and Pharmacology, University of Rome La Sapienza, Rome, Italy; Istituto Neurologico Mediterraneo Neuromed, Pozzilli (IS), Italy.
authors.forename: Silvia
authors.initials: S
authors.lastname: Spadacenta
authors.affiliation: Department of Neuroscience, University of Parma, Parma, Italy.
authors.forename: Vittorio
authors.initials: V
authors.lastname: Gallese
authors.affiliation: Department of Physiology and Pharmacology, University of Rome La Sapienza, Rome, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Fragola
authors.affiliation: Department of Physiology and Pharmacology, University of Rome La Sapienza, Rome, Italy; Istituto Neurologico Mediterraneo Neuromed, Pozzilli (IS), Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Mirabella
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001132:Arm; D004192:Discrimination, Psychological; D004644:Emotions; D006225:Hand; D006801:Humans; D009068:Movement; D012660:Semantics; D014705:Verbal Behavior; D055815:Young Adult
references.citation: Psychon Bull Rev. 2008 Feb;15(1):161-7
references.pmid: 18605497
references.citation: PLoS One. 2013;8(1):e54091
references.pmid: 23349792
references.citation: J Exp Psychol Learn Mem Cogn. 2004 Mar;30(2):382-92
references.pmid: 14979812
references.citation: J Exp Psychol Gen. 2011 Feb;140(1):14-34
references.pmid: 21171803
references.citation: Eur J Neurosci. 2002 Jan;15(2):399-402
references.pmid: 11849307
references.citation: Neuropsychologia. 2003;41(1):53-70
references.pmid: 12427565
references.citation: Cortex. 2012 Jul;48(7):788-804
references.pmid: 21163473
references.citation: Front Psychol. 2013 Nov 26;4:863
references.pmid: 24324449
references.citation: Cereb Cortex. 2014 Jul;24(7):1767-77
references.pmid: 23408565
references.citation: PLoS One. 2012;7(4):e35403
references.pmid: 22536380
references.citation: Cognition. 2008 Aug;108(2):557-65
references.pmid: 18433742
references.citation: Cogn Neuropsychol. 2008 Oct-Dec;25(7-8):996-1010
references.pmid: 19378414
references.citation: Biol Psychol. 2011 May;87(2):265-74
references.pmid: 21440031
references.citation: Cogn Neuropsychol. 2005 May;22(3):480-94
references.pmid: 21038262
references.citation: J Exp Psychol. 1960 Apr;59:239-45
references.pmid: 13832584
references.citation: Cogn Neuropsychol. 2005 May;22(3):455-79
references.pmid: 21038261
references.citation: Neuroimage. 2006 May 1;30(4):1383-400
references.pmid: 16460964
references.citation: Neuropsychologia. 2003;41(2):171-83
references.pmid: 12459215
references.citation: Nat Neurosci. 2001 Jul;4(7):752-8
references.pmid: 11426233
references.citation: Can J Exp Psychol. 2003 Sep;57(3):141-51
references.pmid: 14596473
references.citation: PLoS One. 2013 May 03;8(5):e62793
references.pmid: 23658775
references.citation: Psychol Sci. 2009 Aug;20(8):974-80
references.pmid: 19594858
references.citation: Brain Res. 2007 Jan 26;1130(1):119-24
references.pmid: 17174278
references.citation: Psychol Sci. 2003 Jan;14(1):14-8
references.pmid: 12564748
references.citation: Neurosci Biobehav Rev. 2011 Jan;35(3):407-26
references.pmid: 20451552
references.citation: Q J Exp Psychol (Hove). 2008 Jun;61(6):905-19
references.pmid: 18470821
references.citation: Proc Natl Acad Sci U S A. 2005 May 24;102(21):7713-7
references.pmid: 15897465
references.citation: Emotion. 2009 Oct;9(5):609-18
references.pmid: 19803583
references.citation: Psychon Bull Rev. 2007 Jun;14(3):436-41
references.pmid: 17874584
references.citation: Psychon Bull Rev. 2011 Aug;18(4):742-50
references.pmid: 21494916
references.citation: Front Hum Neurosci. 2013 Feb 01;7:11
references.pmid: 23378833
references.citation: Brain Lang. 2013 Oct;127(1):86-103
references.pmid: 23932167
references.citation: Brain Res Cogn Brain Res. 2005 Aug;24(3):355-63
references.pmid: 16099349
references.citation: J Pers Soc Psychol. 1991 Sep;61(3):380-91
references.pmid: 1941510
references.citation: Behav Brain Sci. 1999 Aug;22(4):577-609; discussion 610-60
references.pmid: 11301525
references.citation: J Exp Psychol Gen. 2014 Jun;143(3):1065-1081
references.pmid: 24490848
references.citation: Hum Brain Mapp. 2004 Mar;21(3):191-201
references.pmid: 14755838
references.citation: Neuropsychologia. 1971 Mar;9(1):97-113
references.pmid: 5146491
references.citation: Front Hum Neurosci. 2012 Oct 08;6:275
references.pmid: 23060778
references.citation: Eur J Neurosci. 2005 Feb;21(3):793-7
references.pmid: 15733097
references.citation: Neuropsychologia. 2008 Jan 31;46(2):743-56
references.pmid: 18037143
references.citation: Brain Lang. 2008 May;105(2):83-90
references.pmid: 18054379