title: [Clinical and epidemiological aspects of medullary thyroid carcinoma in Ukraine].
abstract: Analyzed data from 232 patients with medullary thyroid carcinoma who were treated in the surgical department of the Institute from 1979 to 2012 (inclusive). Found that the analyzed cohort of patients to meet other samples in such characteristics as age of patients and the distribution of the forms of the disease (sporadic, familial, in the syndrome MEN-2B). At the same time it is shown that the number of patients with sporadic medullary carcinoma from the end of the century the alien has increased significantly mainly due to the increase in the number of female patients. Analysis of the distribution of patients in the community shows that the share of the 5 most industrially polluted regions of Ukraine--Donetsk, Dnepropetrovsk, Lugansk, Zaporozhye, Kiev (and Kiev)--more than a third of patients with the sporadic form of medullary carcinoma of the cohort of patients, whereas in share of the best "clean" areas--Chernivtsi, Rivne, Volyn, Ternopil and Zhytomyr--3.6 times less. While noting some patients most of the areas most affected by the Chernobyl accident. The increase in the last decade the number of patients with sporadic medullary thyroid carcinoma, and more than the other samples, the number of female patients showed some features of the causes of this form of the disease among the population of Ukraine and can be due to the adverse impact of environmental factors, especially the female body.
authors.forename: A M
authors.initials: AM
authors.lastname: Kvacheniuk
authors.forename: D V
authors.initials: DV
authors.lastname: Reĭzin
mesh_terms: D000328:Adult; D018278:Carcinoma, Neuroendocrine; D047852:Chernobyl Nuclear Accident; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D013964:Thyroid Neoplasms / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology / Q000601:surgery; D014455:Ukraine / Q000453:epidemiology