title: Acute phase proteins in Andalusian horses infected with Theileria equi.
abstract: Clinical and laboratory findings were determined in 23 Andalusian horses in southern Spain that were positive for Theileria equi by PCR, including 16 mares at pasture (group A1) and seven stabled stallions (group B1). Five healthy mares at pasture (group A2) and five stabled stallions (group B2), all of which were negative for T. equi in Giemsa stained blood smears and by PCR, were used as controls. The most frequent clinical signs were anorexia, anaemia, depression and icterus (group A1), along with loss of performance or failure to train and depression (group B1). Thrombocytopoenia was evident in 5/7 horses in group B1. Lower serum iron concentrations were observed in both diseased groups compared with their respective control groups. There were no significant differences in APP concentrations between diseased and control groups; all affected horses had APP concentrations within reference limits. Serum haptoglobin, serum amyloid A and plasma fibrinogen concentrations were higher than the reference limits in 5/23, 3/23 and 1/23 diseased horses, respectively. It was concluded that horses with theileriosis exhibited only a mild systemic inflammatory response.
authors.affiliation: Equine Sport Medicine Centre, CEMEDE, School of Veterinary Medicine, University of Córdoba, 14004 Córdoba, Spain.
authors.forename: Rocío
authors.initials: R
authors.lastname: Rodríguez
authors.affiliation: Department of Animal Medicine and Surgery, School of Veterinary Medicine, Campus of Excellence Mare Nostrum, University of Murcia, 30100 Murcia, Spain.
authors.forename: José J
authors.initials: JJ
authors.lastname: Cerón
authors.affiliation: Equine Sport Medicine Centre, CEMEDE, School of Veterinary Medicine, University of Córdoba, 14004 Córdoba, Spain; Department of Animal Medicine and Surgery, School of Veterinary Medicine, University of Córdoba, Córdoba, Spain.
authors.forename: Cristina
authors.initials: C
authors.lastname: Riber
authors.affiliation: Equine Sport Medicine Centre, CEMEDE, School of Veterinary Medicine, University of Córdoba, 14004 Córdoba, Spain.
authors.forename: Francisco
authors.initials: F
authors.lastname: Castejón
authors.affiliation: Equine Sport Medicine Centre, CEMEDE, School of Veterinary Medicine, University of Córdoba, 14004 Córdoba, Spain.
authors.forename: Manuel
authors.initials: M
authors.lastname: Gómez-Díez
authors.affiliation: Department of Pharmacology, Toxicology, and Legal and Forensic Medicine, School of Veterinary Medicine, University of Córdoba, Córdoba, Spain.
authors.forename: Juan M
authors.initials: JM
authors.lastname: Serrano-Rodríguez
authors.affiliation: Equine Sport Medicine Centre, CEMEDE, School of Veterinary Medicine, University of Córdoba, 14004 Córdoba, Spain; Department of Animal Medicine and Surgery, School of Veterinary Medicine, University of Córdoba, Córdoba, Spain. Electronic address: pv1mujua@uco.es.
authors.forename: Ana
authors.initials: A
authors.lastname: Muñoz
mesh_terms: D000209:Acute-Phase Proteins / Q000378:metabolism*; D000818:Animals; D005260:Female; D006734:Horse Diseases / Q000097:blood* / Q000378:metabolism; D006736:Horses; D008297:Male; D016794:Theileria / Q000145:classification*; D013801:Theileriasis / Q000097:blood* / Q000378:metabolism
chemical_list: D000209:Acute-Phase Proteins
keywords: Acute phase proteins; Clinical pathology; Equine; Theileria equi