title: Bilateral familial elastofibroma dorsi: is genetic abnormality essential?
abstract: Elastofibroma dorsi is a rare, slowly growing, benign soft tissue tumor located in the periscapular region on the chest wall. Although it is generally unilateral, it may be bilateral in 10% of cases. The tumor is located between the costa and the chest wall muscles. The patients generally describe back and shoulder pain that increases with movement. Three sisters, aged 58, 61, and 63 years, who were admitted to our clinic with of bilateral swelling and pain in the infrascapular region, received diagnoses of elastofibroma dorsi after radiologic examination. Bilateral elastofibroma dorsi resection was performed on the three sisters. Inasmuch as cases of elstofibroma dorsi demonstrate familial features, a genetic examination was conducted; however, prominent chromosomal instability was not detected. It is emphasized that the disease might be familial; however, chromosomal changes may not be present.
authors.affiliation: Department of Thoracic Surgery, Dr Suat Seren Chest Disease and Thoracic Surgery Training and Research Hospital, Izmir, Turkey. Electronic address: tevfikilkerakcam@hotmail.com.
authors.forename: Tevfik İlker
authors.initials: Tİ
authors.lastname: Akçam
authors.affiliation: Department of Thoracic Surgery, Faculty of Medicine, EGE University, Izmir, Turkey.
authors.forename: Ufuk
authors.initials: U
authors.lastname: Çağırıcı
authors.affiliation: Department of Thoracic Surgery, Faculty of Medicine, EGE University, Izmir, Turkey.
authors.forename: Alpaslan
authors.initials: A
authors.lastname: Çakan
authors.affiliation: Department of Genetics, Faculty of Medicine, EGE University, Izmir, Turkey.
authors.forename: Haluk
authors.initials: H
authors.lastname: Akın
mesh_terms: D005350:Fibroma / Q000235:genetics* / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D012983:Soft Tissue Neoplasms / Q000235:genetics* / Q000473:pathology; D035441:Thoracic Wall