title: Acute pericarditis as the first manifestation of familial Mediterranean fever: a possible relationship with idiopathic recurrent pericarditis.
abstract: A 56-year-old man was admitted to our hospital due to periodic episodes of acute pericarditis. These episodes occurred monthly along with a high fever and elevation of the C-reactive protein (CRP) level. The patient became afebrile and his CRP level decreased following the administration of a non-steroidal anti-inflammatory drug. A mutation analysis revealed the heterozygote of the familial Mediterranean fever (FMF) gene (E84K, G304R). This finding confirmed our diagnosis, and we treated the patient with colchicine. He responded to treatment and has been visiting our hospital without disease recurrence. FMF should be included in the differential diagnosis of repeated episodes of pericarditis.
authors.affiliation: Department of Internal Medicine, Social Welfare Foundation Shitennoji Hospital, Japan.
authors.forename: Katsunobu
authors.initials: K
authors.lastname: Yoshioka
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Furumitsu
authors.forename: Tatsushi
authors.initials: T
authors.lastname: Sano
authors.forename: Takahiro
authors.initials: T
authors.lastname: Miyamoto
authors.forename: Kazunaga
authors.initials: K
authors.lastname: Agematsu
mesh_terms: D000208:Acute Disease; D002097:C-Reactive Protein / Q000378:metabolism; D003937:Diagnosis, Differential; D004562:Electrocardiography; D010505:Familial Mediterranean Fever / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010493:Pericarditis / Q000175:diagnosis / Q000209:etiology* / Q000378:metabolism; D012008:Recurrence; D014057:Tomography, X-Ray Computed
chemical_list: D002097:C-Reactive Protein