title: A comparison between three-dimensional conformal radiotherapy combined with interventional treatment and interventional treatment alone for hepatocellular carcinoma with portal vein tumour thrombosis.
abstract: BACKGROUND
  We investigated the therapeutic effects of three-dimensional conformal radiotherapy combined with transcatheter arterial chemoembolisation (TACE) for hepatocellular carcinoma (HCC) with portal vein tumour thrombosis (PVTT).
  
  
  METHODS
  Sixty-three HCC patients with PVTT were divided into two groups. Group A (30 patients) was treated with three-dimensional conformal radiotherapy followed by 2-3 series of TACE, while group B (33 patients) was only treated with TACE.
  
  
  RESULTS
  The 1- and 2-year survival rates of group A were 62.40% and 20.81%, respectively, with a mean survival time of 13.0 months. The 1- and 2-year survival rates of group B were 56.49% and 18.83%, respectively, with a mean survival time of 9.0 months. There were significant differences between the two groups (log-rank chi-square value = 3.950, P = 0.047).
  
  
  CONCLUSIONS
  Three-dimensional conformal radiotherapy combined with TACE can significantly improve clinical outcomes in patients with HCC and PVTT compared with TACE alone.
authors.affiliation: Tumor Diagnosis and Treatment Center, 105th Hospital of PLA, Hefei, China.
authors.forename: Dong-Hui
authors.initials: DH
authors.lastname: Lu
authors.forename: Zhen-Le
authors.initials: ZL
authors.lastname: Fei
authors.forename: Jun-Ping
authors.initials: JP
authors.lastname: Zhou
authors.forename: Zong-Tao
authors.initials: ZT
authors.lastname: Hu
authors.forename: Wen-Sheng
authors.initials: WS
authors.lastname: Hao
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000401:mortality* / Q000628:therapy*; D015984:Causality; D016461:Chemoembolization, Therapeutic / Q000401:mortality*; D002681:China / Q000453:epidemiology; D003131:Combined Modality Therapy / Q000401:mortality; D015897:Comorbidity; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011169:Portal Vein; D015995:Prevalence; D050397:Radiotherapy, Intensity-Modulated / Q000401:mortality*; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000401:mortality / Q000628:therapy*
keywords: liver tumour; portal vein tumour thrombosis; three-dimensional conformal radiotherapy; transcatheter arterial chemoembolisation