title: New case of azole-resistant Aspergillus fumigatus due to TR46/Y121F/T289A mutation in Belgium.
authors.affiliation: Department of Microbiology, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik 808, 1070 Brussels, Belgium carlota.montesinos@erasme.ulb.ac.be.
authors.forename: Isabel
authors.initials: I
authors.lastname: Montesinos
authors.affiliation: Department of Microbiology, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik 808, 1070 Brussels, Belgium.
authors.forename: Magali
authors.initials: M
authors.lastname: Dodemont
authors.affiliation: Department of Microbiology and Immunology, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium.
authors.forename: Katrien
authors.initials: K
authors.lastname: Lagrou
authors.affiliation: Department of Infectious Diseases, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik 808, 1070 Brussels, Belgium.
authors.forename: Frederique
authors.initials: F
authors.lastname: Jacobs
authors.affiliation: Department of Pneumology, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik 808, 1070 Brussels, Belgium.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Etienne
authors.affiliation: Department of Microbiology, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik 808, 1070 Brussels, Belgium.
authors.forename: Olivier
authors.initials: O
authors.lastname: Denis
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D001228:Aspergillosis / Q000382:microbiology*; D001232:Aspergillus fumigatus / Q000187:drug effects* / Q000302:isolation & purification; D001393:Azoles / Q000494:pharmacology*; D001530:Belgium; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics*; D025141:Drug Resistance, Fungal; D005656:Fungal Proteins / Q000235:genetics*; D006801:Humans; D020125:Mutation, Missense
chemical_list: D000935:Antifungal Agents; D001393:Azoles; D005656:Fungal Proteins; D003577:Cytochrome P-450 Enzyme System; C465526:cytochrome P-450 CYP51A, Aspergillus
keywords: cyp51A genotyping; invasive aspergillosis; voriconazole high resistance