title: Effect of chlorhexidine chip in the treatment of chronic periodontitis.
abstract: OBJECTIVE
  The evaluation of clinical and specific microbiological changes associated with chlorhexidine chip in the chronic periodontitis patients.
  
  
  METHODS
  A total of 30 chronic periodontitis patients (aged 20-65 years) having pocket depth of ≥5 mm in molar teeth were selected and randomly divided into following treatment groups: Group 1 - Scaling and root planning (SRP), Group 2 - SRP along with chlorhexidine chip and Group 3 - Only chlorhexidine chip. The clinical and microbial parameters were recorded at baseline and 1 and 3 months post-treatment as above. Benzoyl-DL-arginine-naphthylamide (BANA) chair side test was used for estimation of specific microbiota.
  
  
  RESULTS
  Gingival index, probing pocket depth and clinical attachment level scores in selected teeth within the groups at different time intervals was significantly (P < 0.001) different. Although, the comparison between groups for specific microbiota in selected sites at different intervals was not statistically significant at baseline and 1 month, it reached statistical significance at 3(rd) month post-treatment. Although significant reductions in percentage of BANA positive sites were observed in all three groups, the Group 2 had significantly greater percentage of BANA negative sites.
  
  
  CONCLUSIONS
  Local drug delivery using chlorhexidine chip enhances the benefit of SRP in the treatment of chronic periodontitis.
authors.affiliation: Department of Periodontology, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, India.
authors.forename: A Jana
authors.initials: AJ
authors.lastname: Kumar
authors.affiliation: Department of Periodontology, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, India.
authors.forename: B V
authors.initials: BV
authors.lastname: Ramesh Reddy
authors.affiliation: Department of Periodontology, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, India.
authors.forename: Vijay K
authors.initials: VK
authors.lastname: Chava
keywords: N Benzoyl-DL-arginine-β naphthylamide; chlorhexidine; chronic periodontitis; local drug delivery
references.citation: Ann Periodontol. 2003 Dec;8(1):79-98
references.pmid: 14971250
references.citation: J Periodontol. 1993 Aug;64(8 Suppl):782-91
references.pmid: 8410618
references.citation: J Periodontol. 2007 Jun;78(6):997-1001
references.pmid: 17539711
references.citation: J Periodontol. 2008 Feb;79(2):271-82
references.pmid: 18251641
references.citation: J Periodontol. 2007 Apr;78(4):624-8
references.pmid: 17397308
references.citation: J Clin Periodontol. 2002 Oct;29(10):875-81
references.pmid: 12445218
references.citation: J Periodontol. 1998 May;69(5):507-20
references.pmid: 9623893
references.citation: J Periodontol. 2006 Mar;77(3):437-43
references.pmid: 16512758
references.citation: J Clin Periodontol. 2000 Aug;27(8):578-89
references.pmid: 10959784
references.citation: J Clin Periodontol. 2001 Jan;28(1):90-5
references.pmid: 11142674
references.citation: J Clin Periodontol. 2000 Jan;27(1):30-6
references.pmid: 10674959
references.citation: J Dent Res. 1988 Dec;67(12):1505-9
references.pmid: 3198850
references.citation: J Dent Res. 1990 Oct;69(10):1696-702
references.pmid: 2212216
references.citation: J Periodontol. 1993 Sep;64(9):848-52
references.pmid: 8229620
references.citation: J Periodontol. 1998 Sep;69(9):989-97
references.pmid: 9776027
references.citation: J Periodontol. 2006 Feb;77(2):257-64
references.pmid: 16460252
references.citation: J Clin Periodontol. 1997 May;24(5):324-34
references.pmid: 9178112
references.citation: Periodontol 2000. 1996 Feb;10:139-59
references.pmid: 9567941
references.citation: J Periodontol. 1997 Jan;68(1):32-8
references.pmid: 9029449
references.citation: J Periodontal Res. 2002 Oct;37(5):375-9
references.pmid: 12366861