title: Rapid onset of small intestinal perforation after successful steroid treatment in eosinophilic granulomatosis with polyangiitis.
abstract: Eosinophilic granulomatosis with polyangiitis (EGPA) is a disorder characterized by extravascular granulomas, hypereosinophilia, and pulmonary and systemic small-vessel vasculitis. Bowel perforation is a rare but often fatal complication of EGPA. In the present report, we describe a case of small intestinal perforation in a patient with EGPA. Through various examinations, we confirmed the presence of EGPA, and the patient responded well to steroid therapy. However, as the patient's condition subsequently worsened, the small intestine was consequently resected. The patient's overall condition improved thereafter. Thus, we believe that careful attention should be paid to intestinal symptoms and perforation in patients with EGPA.
authors.affiliation: a Department of Internal Medicine and Rheumatology , Juntendo University Urayasu Hospital , Chiba , Japan.|b Institute for Environmental and Gender Specific Medicine, Juntendo University School of Medicine , Chiba , Japan.
authors.forename: Keigo
authors.initials: K
authors.lastname: Ikeda
authors.affiliation: c Department of Internal Medicine and Rheumatology , Juntendo University School of Medicine , Tokyo , Japan.
authors.forename: Yoshinari
authors.initials: Y
authors.lastname: Takasaki
authors.affiliation: a Department of Internal Medicine and Rheumatology , Juntendo University Urayasu Hospital , Chiba , Japan.|b Institute for Environmental and Gender Specific Medicine, Juntendo University School of Medicine , Chiba , Japan.
authors.forename: Iwao
authors.initials: I
authors.lastname: Sekigawa
mesh_terms: D000328:Adult; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology*; D013256:Steroids / Q000627:therapeutic use
chemical_list: D013256:Steroids
keywords: EGPA; Intestinal perforation; Necrotizing vasculitis