title: Influence of phosphate-buffered sucrose solution on early graft function in feline renal autotransplantation.
abstract: Graft perfusion with cold heparinized saline has known to induce ischemia and reperfusion injury in feline kidney transplantation. In this study, the effects of phosphate-buffered sucrose solution and heparinized saline solution on early kidney graft function were compared in feline kidney autotransplantation. Perfusion of grafts with or without hypothermic storage with chilled phosphate-buffered sucrose solution prevented ischemia and reperfusion injury despite a very short ischemic time. The results of our study suggest that phosphate-buffered sucrose perfusion and storage solution should be effective to reduce ischemia and reperfusion injury despite a very short ischemic time in feline kidney transplantation.
authors.affiliation: Division of Small Animal Surgery, Iwate University, 3-18-8 Ueda, Morioka, Iwate 020-8550, Japan. Electronic address: masaaki@iwate-u.ac.jp.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Katayama
authors.affiliation: Division of Small Animal Surgery, Iwate University, 3-18-8 Ueda, Morioka, Iwate 020-8550, Japan.
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Okamura
authors.affiliation: Small Animal Internal Medicine, Co-Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, 3-18-8 Ueda, Morioka, Iwate 020-8550, Japan.
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Shimamura
authors.affiliation: Division of Small Animal Surgery, Iwate University, 3-18-8 Ueda, Morioka, Iwate 020-8550, Japan.
authors.forename: Rieko
authors.initials: R
authors.lastname: Katayama
authors.affiliation: Division of Veterinary Clinical Radiology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu, Gifu 501-1193, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Kamishina
authors.affiliation: Division of Small Animal Surgery, Iwate University, 3-18-8 Ueda, Morioka, Iwate 020-8550, Japan.
authors.forename: Yuji
authors.initials: Y
authors.lastname: Uzuka
mesh_terms: D000818:Animals; D002021:Buffers; D002371:Cat Diseases / Q000517:prevention & control*; D002415:Cats / Q000601:surgery*; D005260:Female; D007668:Kidney / Q000098:blood supply / Q000601:surgery; D016030:Kidney Transplantation / Q000379:methods / Q000662:veterinary*; D008297:Male; D009392:Nephrectomy; D010710:Phosphates; D015427:Reperfusion Injury / Q000517:prevention & control / Q000662:veterinary*; D012965:Sodium Chloride / Q000627:therapeutic use; D013395:Sucrose / Q000627:therapeutic use*; D014182:Transplantation, Autologous / Q000379:methods / Q000662:veterinary*
chemical_list: D002021:Buffers; D010710:Phosphates; D012965:Sodium Chloride; D013395:Sucrose
keywords: Delayed graft function; Feline; Ischemia and reperfusion injury; Kidney transplantation