title: Ductal carcinoma in situ in a benign phyllodes tumor of breast: A rare presentation.
abstract: Phyllodes tumor (PT) is an uncommon tumor of female breast. The tumor clinically, radiologically, cytologically as well as histologically can mimic fibroadenoma which is a common tumor of fibroepithelial group. Ductal carcinoma in situ (DCIS) in the epithelial component of PT is very rare. We report a rare case of intermediate grade DCIS arising in a benign PT in a 42-year-old lady. The patient presented with a small nodule in right breast along with serosanguineous discharge from nipple. Ultrasonography and cytology failed to distinguish between fibroadenoma and PT. Histopathological examination following wide local excision displayed the biphasic tumor comprising of benign looking cellular stroma and epithelial lining. It also demonstrated the foci of intermediate grade DCIS without any invasive component. Considering the clinicoradiological profile along with histopathological features, the diagnosis of DCIS in a benign PT of breast was made.
authors.affiliation: DESUN (NEON) Reference Lab, Kolkata, West Bengal, India.
authors.forename: Prithwijit
authors.initials: P
authors.lastname: Ghosh
authors.affiliation: Department of Pathology, Murshidabad Medical College and Hospital, Berhampore, Murshidabad, West Bengal, India.
authors.forename: Kaushik
authors.initials: K
authors.lastname: Saha
keywords: Breast; carcinoma; in situ; phyllodes tumor
references.citation: World J Surg Oncol. 2004 Dec 15;2:46
references.pmid: 15601470
references.citation: Breast Cancer. 2006;13(1):89-94
references.pmid: 16518067
references.citation: J Chin Med Assoc. 2010 Nov;73(11):602-4
references.pmid: 21093830
references.citation: Oncol Lett. 2011 Mar;2(2):223-228
references.pmid: 22866068
references.citation: Eur J Med Res. 2012 Apr 25;17:8
references.pmid: 22534285
references.citation: Singapore Med J. 2008 Nov;49(11):e318-21
references.pmid: 19037540
references.citation: Hum Pathol. 2010 Feb;41(2):293-6
references.pmid: 19896695