title: [Vascular-parenchymal ratio of testes under correction of exposure to combinations of heavy metals salts].
abstract: The results of the study of testes' tissue of 128 immature rats, which get within 60 days drinking water with threshold concentration of salts of copper, zinc, iron, manganese, lead, chromium. It was found that morphological changes of microvasculature was nonspecific and lead to the secondary damage of blood-testis barrier and correlated with changes in testes' parenchymal structures. Fullest possible extent of testicular parenchymal damage occurs in the areas of intensive blood supply, as well as toxic substances in these areas have a longer exposure time. Under exposure combinations of heavy metals salts of organisme the reduction of the vascular streambed in the testes is influenced by intravascular, extravascular intrawall factors. The intensity of vasculature and parenchyma violations of gland depends on duration of exposure combinations of salts of heavy metals. Applying the L-carnitine on the background of intoxication of heavy metal salts partially reduces adverse changes in testes' microvasculature streambed and parenchyma of rats.
authors.forename: A M
authors.initials: AM
authors.lastname: Romaniuk
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Moskalenko
authors.forename: S V
authors.initials: SV
authors.lastname: Sauliak
authors.forename: S D
authors.initials: SD
authors.lastname: Bonchev
authors.forename: R A
authors.initials: RA
authors.lastname: Moskalenko
mesh_terms: D000818:Animals; D001814:Blood-Testis Barrier / Q000187:drug effects / Q000648:ultrastructure; D002331:Carnitine / Q000494:pharmacology*; D004730:Endothelium, Vascular / Q000187:drug effects / Q000648:ultrastructure; D000075322:Heavy Metal Poisoning; D008297:Male; D019216:Metals, Heavy / Q000633:toxicity*; D008855:Microscopy, Electron, Scanning; D011041:Poisoning / Q000188:drug therapy* / Q000473:pathology; D020011:Protective Agents / Q000494:pharmacology*; D051381:Rats; D012492:Salts; D013737:Testis / Q000098:blood supply / Q000187:drug effects* / Q000648:ultrastructure
chemical_list: D019216:Metals, Heavy; D020011:Protective Agents; D012492:Salts; D002331:Carnitine