title: Irritable bowel syndrome: a concise review of current treatment concepts.
abstract: Irritable bowel syndrome (IBS) is one of the most common gastrointestinal disorders causing patients to seek medical treatment. It is relatively resource intensive and the source of significant morbidity. Recent insights into the pathophysiology and treatment of IBS has given clinicians more options than ever to contend with this disorder. The purpose of our paper is to review older, "classic" treatments for IBS as well as newer agents and "alternative" therapies. We discuss the evidence base of these drugs and provide context to help develop appropriate treatment plans for IBS patients.
authors.affiliation: Geoffrey C Wall, Ginelle A Bryant, Michelle M Bottenberg, Erik D Maki, Andrew R Miesner, Department of Pharmacy Practice, Drake University College of Pharmacy, Des Moines, IA 50311, United States.
authors.forename: Geoffrey C
authors.initials: GC
authors.lastname: Wall
authors.affiliation: Geoffrey C Wall, Ginelle A Bryant, Michelle M Bottenberg, Erik D Maki, Andrew R Miesner, Department of Pharmacy Practice, Drake University College of Pharmacy, Des Moines, IA 50311, United States.
authors.forename: Ginelle A
authors.initials: GA
authors.lastname: Bryant
authors.affiliation: Geoffrey C Wall, Ginelle A Bryant, Michelle M Bottenberg, Erik D Maki, Andrew R Miesner, Department of Pharmacy Practice, Drake University College of Pharmacy, Des Moines, IA 50311, United States.
authors.forename: Michelle M
authors.initials: MM
authors.lastname: Bottenberg
authors.affiliation: Geoffrey C Wall, Ginelle A Bryant, Michelle M Bottenberg, Erik D Maki, Andrew R Miesner, Department of Pharmacy Practice, Drake University College of Pharmacy, Des Moines, IA 50311, United States.
authors.forename: Erik D
authors.initials: ED
authors.lastname: Maki
authors.affiliation: Geoffrey C Wall, Ginelle A Bryant, Michelle M Bottenberg, Erik D Maki, Andrew R Miesner, Department of Pharmacy Practice, Drake University College of Pharmacy, Des Moines, IA 50311, United States.
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Miesner
mesh_terms: D000529:Complementary Therapies; D005765:Gastrointestinal Agents / Q000627:therapeutic use*; D006801:Humans; D007422:Intestines / Q000187:drug effects* / Q000382:microbiology / Q000503:physiopathology; D043183:Irritable Bowel Syndrome / Q000175:diagnosis / Q000382:microbiology / Q000503:physiopathology / Q000628:therapy*; D019936:Probiotics / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D005765:Gastrointestinal Agents
keywords: Irritable bowel syndrome; Linaclotide; Lubiprostone; Peppermint oil; Probiotics; Rifaximin
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