title: Evidence-based medicine: a 'hidden threat' for patient safety and surgical innovation?
abstract: We explore the limitations of complete reliance on evidence-based medicine which can be diminished by confounding issues and sampling bias. Other strategies which may be reasonably invoked are discussed.
authors.affiliation: Denver Health Medical Centre, University of Colorado, Department of Orthopaedics, School of Medicine, 777 Bannock Street, Denver, Colorado 80204, USA.
authors.forename: P F
authors.initials: PF
authors.lastname: Stahel
authors.affiliation: Denver Health Medical Centre, University of Colorado, Department of Orthopaedics, School of Medicine, 777 Bannock Street, Denver, Colorado 80204, USA.
authors.forename: C
authors.initials: C
authors.lastname: Mauffrey
mesh_terms: D004059:Diffusion of Innovation; D019317:Evidence-Based Medicine; D006801:Humans; D061214:Patient Safety; D017410:Practice Guidelines as Topic; D017594:Publication Bias; D016032:Randomized Controlled Trials as Topic; D013514:Surgical Procedures, Operative / Q000639:trends
keywords: Evidence-based medicine; Innovation; Patient safety in surgery