title: Ocular vestibular-evoked myogenic potentials (oVEMPs) in response to bone-conducted vertex vibration.
abstract: OBJECTIVE
  To investigate low-frequency vertex bone-conducted (BC) vibration for evoking ocular vestibular myogenic potentials (oVEMPs) and its ability to discriminate between lesioned and healthy ears.
  
  
  METHODS
  oVEMPs were analysed in response to 125-Hz single cycle vertex BC vibration in healthy subjects (n=50) and in patients with severe unilateral vestibular loss (n=10). Both positive and negative initial stimulus motions were used.
  
  
  RESULTS
  In most healthy subjects, vertex BC vibration oVEMPs was successfully and symmetrically evoked from both ears. The response was dependent on the direction of the stimulus motion. The latency was shorter with negative initial stimulus motion; however, a positive initial stimulus motion generated somewhat larger amplitudes. Furthermore, there was no significant response from lesioned ears, whereas oVEMPs from the patients' healthy ears were similar to the responses in healthy subjects.
  
  
  CONCLUSIONS
  The oVEMP low-frequency BC response was dependent on the direction of the initial stimulus motion. Testing oVEMPs in response to low-frequency vertex vibration can discriminate patients with unilateral vestibular function loss from healthy controls.
  
  
  CONCLUSIONS
  Low-frequency vertex BC vibration oVEMPs should be considered a possible clinical screening test to evaluate vestibular function.
authors.affiliation: Department of Otolaryngology, St. Olav Hospital, Trondheim University Hospital, Norwegian University of Science and Technology, Norway. Electronic address: Berit.Holmeslet@ntnu.no.
authors.forename: B
authors.initials: B
authors.lastname: Holmeslet
authors.affiliation: Orthopedic Research Center, St. Olav Hospital, Trondheim University Hospital, Norway.
authors.forename: O A
authors.initials: OA
authors.lastname: Foss
authors.affiliation: Department of Otolaryngology, St. Olav Hospital, Trondheim University Hospital, Norwegian University of Science and Technology, Norway.
authors.forename: V
authors.initials: V
authors.lastname: Bugten
authors.affiliation: Department of Audiology, Karolinska Hospital, Stockholm, Sweden.
authors.forename: K
authors.initials: K
authors.lastname: Brantberg
mesh_terms: D000328:Adult; D000368:Aged; D001844:Bone Conduction / Q000502:physiology*; D005260:Female; D006257:Head / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009038:Motion; D015837:Vestibular Diseases / Q000503:physiopathology*; D058585:Vestibular Evoked Myogenic Potentials / Q000502:physiology*; D014722:Vestibule, Labyrinth / Q000503:physiopathology*; D014732:Vibration; D055815:Young Adult
keywords: BC vibration; Low frequency; Stimulus direction; Vertex; oVEMP