title: Genetic diversity of bovine viral diarrhea viruses in commercial bovine serum batches of Chinese origin.
abstract: Bovine viral diarrhea virus (BVDV) is often detected in commercial bovine serum. BVDV genetic diversity was investigated in commercial bovine serum of Chinese origin. Twenty-two batches of bovine serum were obtained from 10 suppliers with different geographic origins in China, and 20 batches of bovine serum were positive by reverse-transcription polymerase chain reaction (RT-PCR) and sequencing. Phylogenetic reconstructions of partial 5'UTR sequences indicated that the samples examined in this work clustered within the BVDV type 1 and BVDV type 2 genotypes. Interestingly, 3 sample sequences clustered into CSFV. These results suggest a high genetic diversity in Chinese BVDV field isolates. This study will benefit epidemiological surveys of BVDV detected in China.
authors.affiliation: State Key Laboratory for Molecular Biology of Special Economic Animals, Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, People's Republic of China.
authors.forename: Shu-Qin
authors.initials: SQ
authors.lastname: Zhang
authors.affiliation: State Key Laboratory for Molecular Biology of Special Economic Animals, Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, People's Republic of China.
authors.forename: Bin
authors.initials: B
authors.lastname: Tan
authors.affiliation: State Key Laboratory for Molecular Biology of Special Economic Animals, Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, People's Republic of China.
authors.forename: Li
authors.initials: L
authors.lastname: Guo
authors.affiliation: State Key Laboratory for Molecular Biology of Special Economic Animals, Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, People's Republic of China.
authors.forename: Feng-Xue
authors.initials: FX
authors.lastname: Wang
authors.affiliation: State Key Laboratory for Molecular Biology of Special Economic Animals, Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, People's Republic of China.
authors.forename: Hong-Wei
authors.initials: HW
authors.lastname: Zhu
authors.affiliation: State Key Laboratory for Molecular Biology of Special Economic Animals, Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, People's Republic of China.
authors.forename: Yong-Jun
authors.initials: YJ
authors.lastname: Wen
authors.affiliation: State Key Laboratory for Molecular Biology of Special Economic Animals, Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, People's Republic of China. Electronic address: tcscsp@126.com.
authors.forename: Shipeng
authors.initials: S
authors.lastname: Cheng
mesh_terms: D020121:5' Untranslated Regions; D000818:Animals; D002417:Cattle; D002681:China; D001908:Diarrhea Viruses, Bovine Viral / Q000145:classification / Q000235:genetics*; D014644:Genetic Variation; D005838:Genotype; D030243:Hemorrhagic Syndrome, Bovine / Q000821:virology*; D008969:Molecular Sequence Data; D010802:Phylogeny
chemical_list: D020121:5' Untranslated Regions
keywords: Bovine serum; Bovine viral diarrhea virus (BVDV); Genetic diversity