title: Efficacy of short-term intrapulmonary percussive ventilation in patients with chronic obstructive pulmonary disease.
abstract: OBJECTIVE
  We evaluated the effectiveness of intrapulmonary percussive ventilation (IPV) compared to traditional standard chest physical therapy (CPT) in patients with chronic obstructive pulmonary disease (COPD) and productive cough.
  
  
  METHODS
  We conducted a quasi-experimental clinical trial. Twenty patients, 40% female (mean ± SD age: 70 ± 8 years), with COPD and productive cough received a multimodal respiratory treatment including IPV and CPT or a control intervention CPT for 10 days.
  
  
  RESULTS
  PImax, PEmax, heart rate, respiratory rate, SBP, DBP, Likert scale, Borg dyspnea scale and arterial blood gas analysis: PO2, PCO2, pH, HCO3 and SpO2 measurements. All measures were collected at baseline and at the end of the intervention. We used repeated ANOVA to examine the effects of interventions within groups, between-subjects and the within-subjects.
  
  
  RESULTS
  A significant effect of time interaction (F = 7.27; p = 0.015, F = 6.16; p = 0.02 and F = 7.41; p = 0.014) existed for PO2, SpO2 and dyspnea over the moderate COPD and productive cough immediately after the intervention (all, p < 0.02). Both treatments are similarly effective in PImax and PEmax. No significant group effect or group-by-time interaction was detected for any of them, which suggests that both groups improved in the same way.
  
  
  CONCLUSIONS
  This study provides evidence that a short-term combination of IPV and CPT improves PO2, SpO2 and perceived dyspnea than a traditional standard CPT in patients with COPD and productive cough.
authors.affiliation: IRCCS Don Gnocchi Foundation , Milan , Italy .
authors.forename: Amidio
authors.initials: A
authors.lastname: Testa
authors.forename: Silvia
authors.initials: S
authors.lastname: Galeri
authors.forename: Jorge Hugo
authors.initials: JH
authors.lastname: Villafañe
authors.forename: Camilo
authors.initials: C
authors.lastname: Corbellini
authors.forename: Paolo
authors.initials: P
authors.lastname: Pillastrini
authors.forename: Stefano
authors.initials: S
authors.lastname: Negrini
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001784:Blood Gas Analysis; D004417:Dyspnea / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D065228:Non-Randomized Controlled Trials as Topic; D026741:Physical Therapy Modalities; D029424:Pulmonary Disease, Chronic Obstructive / Q000628:therapy*; D012138:Respiratory Therapy / Q000295:instrumentation*; D013909:Thorax; D016896:Treatment Outcome
keywords: Chest; chronic obstructive pulmonary disease; intrapulmonary percussive ventilation; physical therapy