title: Cobalt-catalyzed hydroarylative cyclization of 1,6-enynes with aromatic ketones and esters via C-H activation.
abstract: A highly chemo- and stereoselective cobalt-catalyzed hydroarylative cyclization of 1,6-enynes with aromatic ketones and esters to synthesize functionalized pyrrolidines and dihydrofurans is described. A mechanism involving cobaltacycle triggered C-H activation of aromatic ketones and esters was proposed.
authors.affiliation: Department of Chemistry, National Tsing Hua University , Hsinchu 30013, Taiwan.
authors.forename: Rajagopal
authors.initials: R
authors.lastname: Santhoshkumar
authors.forename: Subramaniyan
authors.initials: S
authors.lastname: Mannathan
authors.forename: Chien-Hong
authors.initials: CH
authors.lastname: Cheng
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D003500:Cyclization; D004952:Esters; D007659:Ketones / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D000480:Alkynes; D004952:Esters; D007659:Ketones; D003035:Cobalt