title: A simple method to shorten the unfolding time of prehydrated hydrophobic intraocular lens.
abstract: OBJECTIVE
  To evaluate the effect of warm ophthalmic viscosurgical devices (OVDs) on the unfolding time of prehydrated hydrophobic acrylic intraocular lenses (IOLs).
  
  
  METHODS
  Experimental study and human trial.
  
  
  METHODS
  Three foldable hydrophobic acrylic IOLs (enVista MX60, AcrySof SN60AT, and Tecnis 1 ZCB00).
  
  
  METHODS
  The unfolding times of 3 kinds of IOLs were measured according to temperature from 26°C to 32°C in a transparent container filled with a mixture of OVDs and balanced salt solution. The unfolding time of each IOL was measured 4 times for each temperature. Unfolding time was defined as the time required for the folded IOL to recover ≥ 90% of its overall optic diameter before folding. In human trials, the unfolding time of the MX60 in a capsular bag filled with 30°C OVDs was compared with that filled with room temperature OVDs for 4 cases in each group.
  
  
  RESULTS
  The unfolding time of the MX60 (215 ± 25 seconds) was significantly longer than that of the SN60AT (28 ± 7 seconds) and the ZCB00 (29 ± 7 seconds) at 26°C (p = 0.013). However, there were no differences in the unfolding time of 3 IOLs at 32°C. In human trials, the unfolding time of the MX60 was shorter in a capsular bag filled with 30°C OVDs (32 ± 13 seconds) than if filled with OVDs kept at room temperature (127 ± 27 seconds; p = 0.029).
  
  
  CONCLUSIONS
  When fast and complete unfolding characteristics are needed, filling the anterior chamber and capsular bag with OVDs warmed to 30°C before IOL implantation is recommended.
authors.affiliation: Department of Ophthalmology, Korea University College of Medicine, Seoul, South Korea.
authors.forename: Youngsub
authors.initials: Y
authors.lastname: Eom
authors.affiliation: Department of Ophthalmology, Korea University College of Medicine, Seoul, South Korea.
authors.forename: Joon Sik
authors.initials: JS
authors.lastname: Lee
authors.affiliation: Department of Ophthalmology, Korea University College of Medicine, Seoul, South Korea.
authors.forename: Jay Won
authors.initials: JW
authors.lastname: Rhim
authors.affiliation: Department of Ophthalmology, Korea University College of Medicine, Seoul, South Korea.
authors.forename: Su-Yeon
authors.initials: SY
authors.lastname: Kang
authors.affiliation: Department of Ophthalmology, Korea University College of Medicine, Seoul, South Korea.
authors.forename: Jong Suk
authors.initials: JS
authors.lastname: Song
authors.affiliation: Department of Ophthalmology, Korea University College of Medicine, Seoul, South Korea. Electronic address: hyomkim@hanmail.net.
authors.forename: Hyo Myung
authors.initials: HM
authors.lastname: Kim
mesh_terms: D000180:Acrylic Resins; D006358:Hot Temperature; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D019654:Lens Implantation, Intraocular / Q000379:methods*; D007910:Lenses, Intraocular; D018918:Phacoemulsification; D013997:Time Factors; D055675:Viscosupplements / Q000737:chemistry*
chemical_list: D000180:Acrylic Resins; D055675:Viscosupplements