title: Dendrimersomes with photodegradable membranes for triggered release of hydrophilic and hydrophobic cargo.
abstract: Amphiphilic Janus dendrimers containing first through third generation (G1-G3) photodegradable hydrophobic blocks were synthesized and their self-assembly in water was studied. While the G1 and G2 systems formed solid aggregates, the G3 system self-assembled to form dendrimersomes. These dendrimersomes were demonstrated to degrade upon irradiation with UV light, and exhibited triggered release of both hydrophobic and hydrophilic payloads.
authors.affiliation: Department of Chemistry, The University of Western Ontario, London, ON N6G 5B7, Canada. egillie@uwo.ca.
authors.forename: Ali
authors.initials: A
authors.lastname: Nazemi
authors.forename: Elizabeth R
authors.initials: ER
authors.lastname: Gillies