title: Multicentric evaluation of strategies for treatment of T1a glottic carcinomas.
abstract: The aim of this study was to evaluate the practices of ENT surgeons for the management of early glottic cancers affecting only one vocal cord, i.e. classified T1a. A questionnaire was sent to different surgeons managing cancers of the larynx in France, Belgium and Switzerland. A descriptive and comparative analysis of practices across centers was performed. The decision-making parameters of the therapeutic strategy were analyzed. Sixty-nine surgeons completed the questionnaire (58 in France, 10 in Belgium and one in Switzerland). In the example of a 50-year-old man with active tobacco use and no oncologic history presenting a squamous cell carcinoma of the middle third of the vocal cord classified T1aN0M0, and with easy glottic exposition by laryngoscopy, 91 % of surgeons proposed endoscopic surgery laser, 2 % radiotherapy and 7 % proposed one of these two treatments without any preference. Therapeutic strategies were not influenced by the sex (p = 1.00), the smoking status (p = 0.58) or the age of the patient (more or less than 80 years, p = 0.27). A significant change was observed in the therapeutic strategy for tumors non-exposable by laryngoscopy (p = 0.032), tumors reaching the anterior commissure (p = 0.001) and patients using their voice professionally (p = 0.0003). The management strategy of T1a glottic carcinomas, in our series, is mainly surgical. The choice of therapeutic strategy seems to be based, in our series, on criteria such as the risk of a second location, cost, and duration of treatment.
authors.affiliation: Service d'ORL et Chirurgie Cervico-Faciale, Assistance Publique-Hôpitaux de Marseille (AP-HM)/Aix-Marseille Univ, Centre Hospitalier Universitaire la Timone, 264 rue Saint Pierre, 13385, Marseille Cedex 05, France, nicolas.fakhry@ap-hm.fr.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Fakhry
authors.forename: Sébastien
authors.initials: S
authors.lastname: Vergez
authors.forename: Karine
authors.initials: K
authors.lastname: Baumstarck
authors.forename: Aude
authors.initials: A
authors.lastname: Lagier
authors.forename: Laure
authors.initials: L
authors.lastname: Santini
authors.forename: Patrick
authors.initials: P
authors.lastname: Dessi
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Babin
authors.forename: Antoine
authors.initials: A
authors.lastname: Giovanni
mesh_terms: D001530:Belgium; D003131:Combined Modality Therapy / Q000592:standards; D019468:Disease Management; D005602:France; D005931:Glottis; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D017410:Practice Guidelines as Topic; D011795:Surveys and Questionnaires; D013557:Switzerland
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