title: Removal of amino groups from anilines through diazonium salt-based reactions.
abstract: This minireview describes the applications of in situ generated diazonium salts from anilines in organic synthesis. In situ generation of diazonium salts from anilines represents an efficient and practical pathway, leading to a series of useful structures. In these transformations, the amino group of aniline formally acts as a leaving group. Two distinctive kinds of mechanisms, including transition metal (especially palladium)-catalyzed oxidative addition-reductive elimination and a radical process, are involved in the removal of amino groups from anilines, and both catalytic processes are described in this minireview.
authors.affiliation: Department of Hepatology Disease, Shanghai Shuguang Hospital, Shanghai University of T.C.M., Shanghai 201203, China. gaoyueqiu@hotmail.com.
authors.forename: Linman
authors.initials: L
authors.lastname: He
authors.forename: Guanyinsheng
authors.initials: G
authors.lastname: Qiu
authors.forename: Yueqiu
authors.initials: Y
authors.lastname: Gao
authors.forename: Jie
authors.initials: J
authors.lastname: Wu
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D003641:Deamination; D003979:Diazonium Compounds / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry
chemical_list: D000814:Aniline Compounds; D003979:Diazonium Compounds; D010165:Palladium; D003300:Copper