title: Biofeedback-guided pelvic floor exercise therapy for obstructive defecation: an effective alternative.
abstract: OBJECTIVE
  To compare biofeedback-guided pelvic floor exercise therapy (BFT) with the use of oral polyethylene glycol (PEG) for the treatment of obstructive defecation.
  
  
  METHODS
  A total of 88 subjects were assigned to treatment with either BFT (n = 44) or oral PEG (n = 44). Constipation symptoms (including difficult evacuation, hard stool, digitation necessity, incomplete emptying sensation, laxative dependence, perianal pain at defecation, and constipation satisfaction), Wexner Scores, and quality of life scores were assessed after 1, 3, and 6 mo.
  
  
  RESULTS
  At the 6 mo follow-up, the symptoms of the BFT group patients showed significantly greater improvements compared with the PEG group regarding difficult evacuation, hard stools, digitation necessity, laxative dependence, perianal pain at defecation, constipation satisfaction, Wexner Constipation Score, and quality of life score (P < 0.05). The quality of life score of the BFT group at the final follow-up time (6 mo) was 80 ± 2.2. After a complete course of training, improvements in the clinical symptoms of the BFT group were markedly improved (P < 0.05), and the Wexner Constipation Scores were greatly decreased compared with the oral PEG group (P < 0.05).
  
  
  CONCLUSIONS
  We concluded that manometric biofeedback-guided pelvic floor exercise training is superior to oral polyethylene glycol therapy for obstructive defecation.
authors.affiliation: Ma-Mu-Ti-Jiang A ba-bai-ke-re, Tuerhongjiang Tuxun, Aierhati Husaiyin, Yalikun Sailai, Alimujiang Abulimiti, Liang Zhao, General Surgical Department of First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China.
authors.forename: Ma-Mu-Ti-Jiang A
authors.initials: MM
authors.lastname: Ba-Bai-Ke-Re
authors.affiliation: Ma-Mu-Ti-Jiang A ba-bai-ke-re, Tuerhongjiang Tuxun, Aierhati Husaiyin, Yalikun Sailai, Alimujiang Abulimiti, Liang Zhao, General Surgical Department of First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China.
authors.forename: Ni-Re
authors.initials: NR
authors.lastname: Wen
authors.affiliation: Ma-Mu-Ti-Jiang A ba-bai-ke-re, Tuerhongjiang Tuxun, Aierhati Husaiyin, Yalikun Sailai, Alimujiang Abulimiti, Liang Zhao, General Surgical Department of First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China.
authors.forename: Yun-Long
authors.initials: YL
authors.lastname: Hu
authors.affiliation: Ma-Mu-Ti-Jiang A ba-bai-ke-re, Tuerhongjiang Tuxun, Aierhati Husaiyin, Yalikun Sailai, Alimujiang Abulimiti, Liang Zhao, General Surgical Department of First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Zhao
authors.affiliation: Ma-Mu-Ti-Jiang A ba-bai-ke-re, Tuerhongjiang Tuxun, Aierhati Husaiyin, Yalikun Sailai, Alimujiang Abulimiti, Liang Zhao, General Surgical Department of First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China.
authors.forename: Tuerhongjiang
authors.initials: T
authors.lastname: Tuxun
authors.affiliation: Ma-Mu-Ti-Jiang A ba-bai-ke-re, Tuerhongjiang Tuxun, Aierhati Husaiyin, Yalikun Sailai, Alimujiang Abulimiti, Liang Zhao, General Surgical Department of First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China.
authors.forename: Aierhati
authors.initials: A
authors.lastname: Husaiyin
authors.affiliation: Ma-Mu-Ti-Jiang A ba-bai-ke-re, Tuerhongjiang Tuxun, Aierhati Husaiyin, Yalikun Sailai, Alimujiang Abulimiti, Liang Zhao, General Surgical Department of First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China.
authors.forename: Yalikun
authors.initials: Y
authors.lastname: Sailai
authors.affiliation: Ma-Mu-Ti-Jiang A ba-bai-ke-re, Tuerhongjiang Tuxun, Aierhati Husaiyin, Yalikun Sailai, Alimujiang Abulimiti, Liang Zhao, General Surgical Department of First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China.
authors.forename: Alimujiang
authors.initials: A
authors.lastname: Abulimiti
authors.affiliation: Ma-Mu-Ti-Jiang A ba-bai-ke-re, Tuerhongjiang Tuxun, Aierhati Husaiyin, Yalikun Sailai, Alimujiang Abulimiti, Liang Zhao, General Surgical Department of First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China.
authors.forename: Yun-Hai
authors.initials: YH
authors.lastname: Wang
authors.affiliation: Ma-Mu-Ti-Jiang A ba-bai-ke-re, Tuerhongjiang Tuxun, Aierhati Husaiyin, Yalikun Sailai, Alimujiang Abulimiti, Liang Zhao, General Surgical Department of First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Yang
mesh_terms: D000284:Administration, Oral; D001676:Biofeedback, Psychology / Q000379:methods*; D002681:China; D003248:Constipation / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D003672:Defecation / Q000187:drug effects*; D006801:Humans; D054368:Laxatives / Q000008:administration & dosage*; D008365:Manometry; D008875:Middle Aged; D017060:Patient Satisfaction; D017773:Pelvic Floor / Q000294:innervation*; D011092:Polyethylene Glycols / Q000008:administration & dosage*; D011788:Quality of Life; D020127:Recovery of Function; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D054368:Laxatives; D011092:Polyethylene Glycols
keywords: Biofeedback; Obstructive defecation; Polyethylene glycol
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