title: Changes of anterior chamber architecture induced by laser peripheral iridotomy in acute angle closure crisis.
abstract: In acute angle closure crisis (AAC), a laser peripheral iridotomy (LPI) is performed to balance the pressure gradient between anterior and posterior chamber. The hereby induced changes in anterior chamber architecture were analyzed using Scheimpflug photography (SP). SP was performed in eyes with AAC and in fellow eyes (FE) before and after LPI. Intraocular pressure (IOP), anterior chamber volume (ACV), anterior chamber depth (ACD), anterior chamber angle width (ACA), and central corneal thickness (CCT) were analyzed. The group consisted of 18 patients (14♀, 4♂; 69 ± 11 years) with unilateral AAC. Mean IOP in AAC eyes decreased from 49.3 ± 2.8 mmHg at presentation to 13.7 ± 1.6 mmHg after LPI (p = 0.001). Mean ACV increased from 48.2 ± 3.6 to 60.6 ± 2.4 mm(3) in AAC eyes (p < 0.001) and from 60.4 ± 4.6 to 74.1 ± 3.7 mm(3) in the FE (p < 0.001). Mean ACD increased from 1.27 ± 0.08 to 1.44 ± 0.06 mm (p = 0.01) in AAC eyes and decreased in FE from 1.72 ± 0.08 to 1.59 ± 0.04 mm (p = 0.5). Mean ACA increased from 16.8 ± 1.6 to 20.5 ± 1.5° in AAC eyes (p = 0.01) and from 18.5 ± 1.4 to 22.6 ± 1.5° in the FE (p = 0.01). Mean CCT did not change significantly in both groups after LPI (AAC p = 0.09; FE p = 0.9) but a statistically significant difference between the two groups was detectable before LPI (p = 0.04) which disappeared thereafter (p = 0.14). Using Scheimpflug photography, a significant difference of ACV, ACD, and ACA can be detected after LPI in eyes suffering from acute angle closure crisis which demonstrates the effectiveness of LPI.
authors.affiliation: University Eye Clinic, Liebigstrasse 10-14, Leipzig, 04103, Germany, jandarius.unterlauft@medizin.uni-leipzig.de.
authors.forename: J D
authors.initials: JD
authors.lastname: Unterlauft
authors.forename: Y
authors.initials: Y
authors.lastname: Yafai
authors.forename: P
authors.initials: P
authors.lastname: Wiedemann
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D000867:Anterior Chamber / Q000473:pathology* / Q000601:surgery; D058452:Axial Length, Eye; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D032801:Iridectomy / Q000009:adverse effects* / Q000379:methods; D007498:Iris / Q000601:surgery; D053844:Lasers, Solid-State / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014792:Visual Acuity
references.citation: Ophthalmology. 2004 Aug;111(8):1475-9
references.pmid: 15288974
references.citation: Br J Ophthalmol. 1996 May;80(5):389-93
references.pmid: 8695555
references.citation: Cornea. 2009 Jul;28(6):657-66
references.pmid: 19512905
references.citation: Invest Ophthalmol Vis Sci. 2013 May 01;54(5):3763-70
references.pmid: 23661374
references.citation: Clin Exp Optom. 2009 Mar;92(2):110-8
references.pmid: 18983633
references.citation: Arch Ophthalmol. 1997 Nov;115(11):1436-40
references.pmid: 9366676
references.citation: Ophthalmologe. 2006 Jan;103(1):35-9
references.pmid: 15983778
references.citation: J Cataract Refract Surg. 2009 Jan;35(1):127-33
references.pmid: 19101435
references.citation: AMA Arch Ophthalmol. 1957 Oct;58(4):510-2
references.pmid: 13457548
references.citation: Eur J Ophthalmol. 2010 May-Jun;20(3):517-22
references.pmid: 20037901
references.citation: Yan Ke Xue Bao. 1994 Sep;10(3):176-85
references.pmid: 7744211
references.citation: Clin Exp Ophthalmol. 2010 Jan;38(1):10-4
references.pmid: 20447095
references.citation: J Glaucoma. 2013 Dec;22(9):776-9
references.pmid: 22668977
references.citation: Eur J Ophthalmol. 2012 May 14;:0
references.pmid: 22610719
references.citation: Am J Ophthalmol. 1997 Jul;124(1):53-60
references.pmid: 9222233
references.citation: J Cataract Refract Surg. 2008 Jan;34(1):103-13
references.pmid: 18165089
references.citation: Trans Am Acad Ophthalmol Otolaryngol. 1960 Mar-Apr;64:112-27
references.pmid: 14445374
references.citation: Ophthalmology. 1992 Oct;99(10):1499-504
references.pmid: 1454314
references.citation: Br J Ophthalmol. 2007 Nov;91(11):1485-9
references.pmid: 17504852
references.citation: Clin Exp Ophthalmol. 2000 Aug;28(4):253-8
references.pmid: 11021552
references.citation: Invest Ophthalmol Vis Sci. 2013 May 03;54(5):3166-70
references.pmid: 23599331
references.citation: Ophthalmology. 2000 May;107(5):998-1003
references.pmid: 10811096
references.citation: Eye (Lond). 2005 Dec;19(12):1271-5
references.pmid: 15565188
references.citation: J Cataract Refract Surg. 2006 Nov;32(11):1803-8
references.pmid: 17081861
references.citation: Acta Ophthalmol (Copenh). 1974;52(4):551-64
references.pmid: 4479061
references.citation: Br J Ophthalmol. 1973 Jul;57(7):471-4
references.pmid: 4725855
references.citation: Klin Monbl Augenheilkd. 2008 Mar;225(3):194-9
references.pmid: 18351532
references.citation: Trans Ophthalmol Soc U K. 1971;91:709-39
references.pmid: 5291556
references.citation: Trans Ophthalmol Soc U K. 1977 Apr;97(1):189-91
references.pmid: 271393
references.citation: Br J Ophthalmol. 1970 Mar;54(3):161-9
references.pmid: 5428641
references.citation: Clin Exp Ophthalmol. 2010 Nov;38(8):778-85
references.pmid: 20572815