title: The falling incidence of hematologic cancer after heart transplantation.
abstract: BACKGROUND
  A number of changes in the management of heart transplantation (HT) patients have each tended to reduce the risk of post-HT hematologic cancer, but little information is available concerning the overall effect on incidence in the HT population.
  
  
  METHODS
  Comparison of data from the Spanish Post-Heart-Transplantation Tumour Registry for the periods 1991-2000 and 2001-2010.
  
  
  RESULTS
  The incidence among patients who underwent HT in the latter period was about half that observed in the former, with a particularly marked improvement in regard to incidence more than five yr post-HT.
  
  
  CONCLUSIONS
  Changes in HT patient management have jointly reduced the risk of hematologic cancer in the Spanish HT population. Long-term risk appears to have benefited more than short-term risk.
authors.affiliation: Hospital Universitario A Coruña, La Coruña, Spain.
authors.forename: M G
authors.initials: MG
authors.lastname: Crespo-Leiro
authors.forename: J
authors.initials: J
authors.lastname: Delgado-Jiménez
authors.forename: L
authors.initials: L
authors.lastname: López
authors.forename: L
authors.initials: L
authors.lastname: Alonso-Pulpón
authors.forename: F
authors.initials: F
authors.lastname: González-Vilchez
authors.forename: L
authors.initials: L
authors.lastname: Almenar-Bonet
authors.forename: G
authors.initials: G
authors.lastname: Rábago
authors.forename: F
authors.initials: F
authors.lastname: Pérez-Villa
authors.forename: M J
authors.initials: MJ
authors.lastname: Paniagua Martín
authors.forename: J M
authors.initials: JM
authors.lastname: Arizón Del Prado
authors.forename: I
authors.initials: I
authors.lastname: Sousa-Casasnovas
authors.forename: N
authors.initials: N
authors.lastname: Manito-Lorite
authors.forename: B
authors.initials: B
authors.lastname: Díaz-Molina
authors.forename: D
authors.initials: D
authors.lastname: Pascual-Figal
authors.forename: E
authors.initials: E
authors.lastname: Lage-Galle
authors.forename: T
authors.initials: T
authors.lastname: Blasco-Peiró
authors.forename: L
authors.initials: L
authors.lastname: De la Fuente-Galán
authors.forename: J
authors.initials: J
authors.lastname: Muñiz
mesh_terms: D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000601:surgery; D016027:Heart Transplantation / Q000706:statistics & numerical data*; D019337:Hematologic Neoplasms / Q000453:epidemiology* / Q000517:prevention & control; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012042:Registries; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology
keywords: cancer incidence; heart transplantation; immunosuppressive therapy; long-term complications; lymphomas; mortality