title: Respiratory failure during infusion of pamidronate in a 3 year-old male with osteogenesis imperfecta: a case report.
abstract: Bisphosphonates are being used more frequently as part of the multi-disciplinary management of moderate to severe Osteogenesis Imperfecta (OI). This report details the development of respiratory failure during the second infusion of pamidronate in a 3.5 year-old male with osteogenesis imperfecta type 1 and no prior history of respiratory disease.
authors.affiliation: Department of Endocrinology, UCSF Benioff Children's Hospital Oakland, 757 52nd Street, Oakland, CA 94609, USA. Tel.: +1 510 428 3654; Fax: +1 510 450 5614; E-mail: JeOlson@mail.cho.org.
authors.forename: Jennifer Ann
authors.initials: JA
authors.lastname: Olson
mesh_terms: D050071:Bone Density Conservation Agents / Q000009:adverse effects*; D002675:Child, Preschool; D004164:Diphosphonates / Q000009:adverse effects*; D006801:Humans; D007262:Infusions, Intravenous / Q000009:adverse effects; D008297:Male; D010013:Osteogenesis Imperfecta / Q000188:drug therapy*; D000077268:Pamidronate; D012131:Respiratory Insufficiency / Q000139:chemically induced*; D016896:Treatment Outcome
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D000077268:Pamidronate
keywords: Osteogenesis imperfecta; bisphosphonates; pamidronate; respiratory distress; respiratory failure