title: The impact of anxious symptoms in the remission of depressive symptoms in a clinical trial for depression: follow-up of six months.
abstract: BACKGROUND
  Studies show high comorbidity between anxiety disorder and depression. Little is known regarding how anxiety symptoms affect prognosis in depression treatment, suggesting the importance of studying the impact of anxiety symptoms in the treatment of depression. We evaluated the impact of anxiety symptoms in the remission of depressive symptoms after brief psychotherapies for depression.
  
  
  METHODS
  This randomized clinical trial of 18-29-year-old adults included individuals who met the diagnostic criteria for depression as assessed by the Structured Clinical Interview for DSM (SCID). Depressive symptoms were assessed using the Hamilton Rating Scale for Depression (HRSD); anxiety symptoms were assessed using the Hamilton Anxiety Rating Scale (HARS). The protocols of psychotherapy used were: Cognitive Narrative Psychotherapy (CNP) and Cognitive Behavioral Psychotherapy (CBP). Both treatments included seven sessions. At the end of the treatment and six-month follow-up, an evaluation was made with the HRSD and HARS. The sample included 97 patients divided between the protocols of psychotherapy.
  
  
  RESULTS
  There was a significant, positive, moderate correlation between the severity of anxiety symptoms at baseline and the remission of depressive symptoms at post-intervention (r=0.38 p<0.001) as well as a significant, positive, low correlation at follow up (r=0.20 p=0.049). We found remission of anxiety symptoms and depressive symptoms after brief psychotherapies, and the remission persisted at follow up.
  
  
  CONCLUSIONS
  We did not evaluate the diagnosis of anxiety disorders.
  
  
  CONCLUSIONS
  The severity of anxiety symptoms did not compromise the treatment focused primarily on depressive symptoms.
authors.affiliation: Universidade Católica de Pelotas-Programa de pós-graduação em Saúde e Comportamento, Rua Gonçalves Chaves, 373, Sala 416C, Centro CEP 96015-560, Brazil.
authors.forename: Taiane
authors.initials: T
authors.lastname: de Azevedo Cardoso
authors.affiliation: Universidade Católica de Pelotas-Programa de pós-graduação em Saúde e Comportamento, Rua Gonçalves Chaves, 373, Sala 416C, Centro CEP 96015-560, Brazil.
authors.forename: Thaíse Campos
authors.initials: TC
authors.lastname: Mondin
authors.affiliation: Universidade Católica de Pelotas-Programa de pós-graduação em Saúde e Comportamento, Rua Gonçalves Chaves, 373, Sala 416C, Centro CEP 96015-560, Brazil.
authors.forename: Bárbara Coiro
authors.initials: BC
authors.lastname: Spessato
authors.affiliation: Universidade Católica de Pelotas-Programa de pós-graduação em Saúde e Comportamento, Rua Gonçalves Chaves, 373, Sala 416C, Centro CEP 96015-560, Brazil.
authors.forename: Luciana
authors.initials: L
authors.lastname: de Avila Quevedo
authors.affiliation: Universidade Católica de Pelotas-Programa de pós-graduação em Saúde e Comportamento, Rua Gonçalves Chaves, 373, Sala 416C, Centro CEP 96015-560, Brazil.
authors.forename: Luciano Dias
authors.initials: LD
authors.lastname: de Mattos Souza
authors.affiliation: Universidade Católica de Pelotas-Programa de pós-graduação em Saúde e Comportamento, Rua Gonçalves Chaves, 373, Sala 416C, Centro CEP 96015-560, Brazil.
authors.forename: Ricardo Azevedo
authors.initials: RA
authors.lastname: da Silva
authors.affiliation: Universidade Católica de Pelotas-Programa de pós-graduação em Saúde e Comportamento, Rua Gonçalves Chaves, 373, Sala 416C, Centro CEP 96015-560, Brazil. Electronic address: jansen@ucpel.tche.br.
authors.forename: Karen
authors.initials: K
authors.lastname: Jansen
mesh_terms: D000293:Adolescent; D000328:Adult; D001008:Anxiety Disorders / Q000150:complications* / Q000628:therapy*; D015928:Cognitive Behavioral Therapy / Q000379:methods; D003866:Depressive Disorder / Q000150:complications* / Q000517:prevention & control* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D011614:Psychotherapy, Brief / Q000379:methods; D012074:Remission Induction; D055815:Young Adult
keywords: Anxiety; Cognitive therapy; Depression; Follow-up study; Randomized clinical trial