title: Metabolism-based herbicide resistance and cross-resistance in crop weeds: a threat to herbicide sustainability and global crop production.
abstract: Weedy plant species that have evolved resistance to herbicides due to enhanced metabolic capacity to detoxify herbicides (metabolic resistance) are a major issue. Metabolic herbicide resistance in weedy plant species first became evident in the 1980s in Australia (in Lolium rigidum) and the United Kingdom (in Alopecurus myosuroides) and is now increasingly recognized in several crop-weed species as a looming threat to herbicide sustainability and thus world crop production. Metabolic resistance often confers resistance to herbicides of different chemical groups and sites of action and can extend to new herbicide(s). Cytochrome P450 monooxygenase, glycosyl transferase, and glutathione S-transferase are often implicated in herbicide metabolic resistance. However, precise biochemical and molecular genetic elucidation of metabolic resistance had been stalled until recently. Complex cytochrome P450 superfamilies, high genetic diversity in metabolic resistant weedy plant species (especially cross-pollinated species), and the complexity of genetic control of metabolic resistance have all been barriers to advances in understanding metabolic herbicide resistance. However, next-generation sequencing technologies and transcriptome-wide gene expression profiling are now revealing the genes endowing metabolic herbicide resistance in plants. This Update presents an historical review to current understanding of metabolic herbicide resistance evolution in weedy plant species.
authors.affiliation: Australian Herbicide Resistance Initiative, School of Plant Biology, University of Western Australia, Western Australia 6009, Australia.
authors.forename: Qin
authors.initials: Q
authors.lastname: Yu
authors.affiliation: Australian Herbicide Resistance Initiative, School of Plant Biology, University of Western Australia, Western Australia 6009, Australia stephen.powles@uwa.edu.au.
authors.forename: Stephen
authors.initials: S
authors.lastname: Powles
mesh_terms: D001315:Australia; D005075:Biological Evolution; D018556:Crops, Agricultural / Q000254:growth & development*; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics; D005982:Glutathione Transferase / Q000235:genetics; D053209:Herbicide Resistance; D006540:Herbicides / Q000494:pharmacology*; D008129:Lolium / Q000187:drug effects / Q000502:physiology; D010940:Plant Proteins / Q000235:genetics; D057685:Plant Weeds / Q000187:drug effects* / Q000502:physiology; D006109:Poaceae / Q000187:drug effects* / Q000502:physiology; D006113:United Kingdom
chemical_list: D006540:Herbicides; D010940:Plant Proteins; D003577:Cytochrome P-450 Enzyme System; D005982:Glutathione Transferase
references.citation: Pest Manag Sci. 2008 Dec;64(12):1229-36
references.pmid: 18636424
references.citation: Trends Plant Sci. 2007 Jan;12(1):6-13
references.pmid: 17161644
references.citation: J Agric Food Chem. 2000 Jul;48(7):2986-90
references.pmid: 10898653
references.citation: J Agric Food Chem. 1979 May-Jun;27(3):615-23
references.pmid: 447934
references.citation: Arch Biochem Biophys. 2010 Jan 1;493(1):53-61
references.pmid: 19577534
references.citation: Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):5812-7
references.pmid: 23530204
references.citation: Pest Manag Sci. 2013 Feb;69(2):176-87
references.pmid: 22614948
references.citation: J Agric Food Chem. 2009 May 13;57(9):3653-60
references.pmid: 19323496
references.citation: Theor Appl Genet. 2005 Apr;110(6):1154-66
references.pmid: 15756534
references.citation: Annu Rev Plant Physiol Plant Mol Biol. 1996 Jun;47:127-158
references.pmid: 15012285
references.citation: Plant Physiol. 1991 May;96(1):104-9
references.pmid: 16668137
references.citation: J Toxicol Environ Health. 1993 Feb;38(2):199-223
references.pmid: 8433403
references.citation: Plant Physiol. 2013 Sep;163(1):363-77
references.pmid: 23872617
references.citation: Plant J. 1999 May;18(3):285-92
references.pmid: 10377994
references.citation: Heredity (Edinb). 2011 May;106(5):817-24
references.pmid: 20877397
references.citation: Plant Physiol. 2014 Apr 23;165(2):618-629
references.pmid: 24760819
references.citation: Heredity (Edinb). 2005 Dec;95(6):485-92
references.pmid: 16175194
references.citation: Drug Metab Rev. 2011 May;43(2):266-80
references.pmid: 21425939
references.citation: Pest Manag Sci. 2012 Jul;68(7):1077-82
references.pmid: 22383419
references.citation: Pest Manag Sci. 2001 Jul;57(7):587-97
references.pmid: 11464789
references.citation: Plant Physiol. 1992 Dec;100(4):1909-13
references.pmid: 16653216
references.citation: Annu Rev Entomol. 2007;52:231-53
references.pmid: 16925478
references.citation: Pest Manag Sci. 2014 Sep;70(9):1340-50
references.pmid: 24338926
references.citation: Heredity (Edinb). 2013 Mar;110(3):220-31
references.pmid: 23047200
references.citation: Pest Manag Sci. 2014 Apr;70(4):549-58
references.pmid: 23650123
references.citation: Anal Chem. 2014 Apr 1;86(7):3525-32
references.pmid: 24568686
references.citation: Plant Physiol. 1990 Nov;94(3):1180-6
references.pmid: 16667814
references.citation: Plant Physiol. 1996 Jun;111(2):349-353
references.pmid: 12226292
references.citation: Evol Appl. 2013 Feb;6(2):231-42
references.pmid: 23798973
references.citation: PLoS One. 2013 May 16;8(5):e63576
references.pmid: 23696834
references.citation: Annu Rev Plant Biol. 2003;54:629-67
references.pmid: 14503006
references.citation: Plant Physiol. 2014 Nov;166(3):1232-40
references.pmid: 24406793
references.citation: New Phytol. 2005 Sep;167(3):787-96
references.pmid: 16101915
references.citation: Pest Manag Sci. 2013 Dec;69(12):1379-84
references.pmid: 23423954
references.citation: Plant Physiol. 1991 Nov;97(3):1026-34
references.pmid: 16668486
references.citation: Curr Opin Biotechnol. 2003 Apr;14(2):151-62
references.pmid: 12732316
references.citation: Pest Manag Sci. 2013 Sep;69(9):996-1000
references.pmid: 23785039
references.citation: Nat Biotechnol. 2007 Nov;25(11):1307-13
references.pmid: 17982444
references.citation: Plant Cell Environ. 2013 Apr;36(4):818-27
references.pmid: 23046181
references.citation: Plant Physiol. 2010 May;153(1):319-26
references.pmid: 20207709
references.citation: Pest Manag Sci. 2015 Jan;71(1):32-9
references.pmid: 24515640
references.citation: Plant Mol Biol. 2006 Aug;61(6):933-43
references.pmid: 16927205
references.citation: Plant Physiol. 1991 Apr;95(4):1036-43
references.pmid: 16668088
references.citation: Trends Plant Sci. 2000 Mar;5(3):116-23
references.pmid: 10707077
references.citation: Plant J. 2014 Jun;78(5):865-76
references.pmid: 24654891
references.citation: Annu Rev Plant Biol. 2010;61:317-47
references.pmid: 20192743