title: Direct validation of the restriction of intramolecular rotation hypothesis via the synthesis of novel ortho-methyl substituted tetraphenylethenes and their application in cell imaging.
abstract: We demonstrate a novel synthetic approach to ortho-methyl substituted tetraphenylethene materials, which can be utilised for directly validating the restriction of intramolecular rotation hypothesis as the basic mechanism of aggregation-induced emission phenomenon and cell imaging.
authors.affiliation: Wuhan National Laboratory for Optoelectronics, School of Optical and Electronic Information, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China. mqzhu@hust.edu.cn mpaldred@hotmail.com.
authors.forename: Guo-Feng
authors.initials: GF
authors.lastname: Zhang
authors.forename: Ze-Qiang
authors.initials: ZQ
authors.lastname: Chen
authors.forename: Matthew P
authors.initials: MP
authors.lastname: Aldred
authors.forename: Zhe
authors.initials: Z
authors.lastname: Hu
authors.forename: Tao
authors.initials: T
authors.lastname: Chen
authors.forename: Zhenli
authors.initials: Z
authors.lastname: Huang
authors.forename: Xianggao
authors.initials: X
authors.lastname: Meng
authors.forename: Ming-Qiang
authors.initials: MQ
authors.lastname: Zhu
mesh_terms: D018360:Crystallography, X-Ray; D005030:Ethylenes / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism; D005456:Fluorescent Dyes / Q000737:chemistry* / Q000378:metabolism; D006367:HeLa Cells; D006801:Humans; D018613:Microscopy, Confocal; D008968:Molecular Conformation
chemical_list: D005030:Ethylenes; D005456:Fluorescent Dyes