title: Pre-exposure prophylaxis for the primary prevention of HIV in at-risk women: empowerment and equity revisited.
abstract: Women continue to bear a disproportionate burden of the HIV epidemic's impact. The last three years have witnessed the explosive emergence of pre-exposure prophylaxis as a viable, woman-initiated, and woman-controlled candidate for the primary prevention of HIV in women. These developments have proven particularly significant for at-risk women in environments where negotiation of safe sex is difficult. In this review, we trace the recent evolution of the pre-exposure prophylaxis vision for women, delineate the clinical trials that made it all possible, and discuss ongoing efforts required for its full actualization.
authors.affiliation: The Warren Alpert Medical School, Brown University, Providence, RI, USA.
authors.forename: Aaron
authors.initials: A
authors.lastname: Kofman
authors.affiliation: The Warren Alpert Medical School, Brown University, Providence, RI, USA.
authors.forename: Eli Y
authors.initials: EY
authors.lastname: Adashi
mesh_terms: D005260:Female; D015658:HIV Infections / Q000453:epidemiology / Q000517:prevention & control* / Q000523:psychology; D006801:Humans; D017008:Negotiating; D011209:Power, Psychological; D065129:Pre-Exposure Prophylaxis; D012307:Risk Factors; D021841:Safe Sex; D014481:United States / Q000453:epidemiology