title: Sources, gastrointestinal absorption and stereo-selective and tissue-specific accumulation of Dechlorane Plus (DP) in chicken.
abstract: Dechlorane Plus (DP) isomers, along with two dechlorinated metabolites were measured in environmental matrices, chyme and digestive tract contents and tissues of chicken from an e-waste recycling site located in South China. Soil is proved to be the main source of DP in chicken rather than food because soil contributes more than 94% of total DP in chyme. In the gastrointestinal tract absorption processes, no selective absorption was observed for DP isomers during the ingestion processes. The tissue distribution of DP isomers in chicken exhibits complicated characteristics. The lipid contents in tissues are the main factors in the tissue distribution of DP, while the different blood perfusion state and the different tissue functions also seem to influence the tissue distribution of DP. The fat, brain, and liver exhibit higher fanti values (0.65, 0.64, and 0.64) than the other tissues (0.54-0.59). The elevated fanti values of DP from the contamination source (0.52 in soil) to chicken suggest stereoselective bioaccumulation of anti-DP in chicken. The similar ratios of anti-Cl11-DP to anti-DP between soil and chicken imply that anti-Cl11-DP mainly derives from the uptake from environment rather than in vivo dechlorination.
authors.affiliation: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China; University of the Chinese Academy of Sciences, Beijing 100049, China.
authors.forename: Xiao-Bo
authors.initials: XB
authors.lastname: Zheng
authors.affiliation: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China. Electronic address: luoxiaoj@gig.ac.cn.
authors.forename: Xiao-Jun
authors.initials: XJ
authors.lastname: Luo
authors.affiliation: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China; University of the Chinese Academy of Sciences, Beijing 100049, China.
authors.forename: Yan-Hong
authors.initials: YH
authors.lastname: Zeng
authors.affiliation: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China.
authors.forename: Jiang-Ping
authors.initials: JP
authors.lastname: Wu
authors.affiliation: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China.
authors.forename: Bi-Xian
authors.initials: BX
authors.lastname: Mai
mesh_terms: D000818:Animals; D002645:Chickens / Q000502:physiology*; D002681:China; D004784:Environmental Monitoring; D005411:Flame Retardants / Q000032:analysis / Q000378:metabolism*; D006843:Hydrocarbons, Chlorinated / Q000032:analysis / Q000378:metabolism*; D007408:Intestinal Absorption; D007536:Isomerism; D011083:Polycyclic Compounds / Q000032:analysis / Q000378:metabolism*; D059027:Recycling; D012987:Soil / Q000737:chemistry; D012989:Soil Pollutants / Q000032:analysis / Q000378:metabolism*
chemical_list: D005411:Flame Retardants; D006843:Hydrocarbons, Chlorinated; D011083:Polycyclic Compounds; D012987:Soil; D012989:Soil Pollutants; C526360:dechlorane plus
keywords: Chicken; Dechlorane Plus; Gastrointestinal absorption; Soil; Tissue distribution