title: Evaluation of quality of life and anxiety and depression levels in patients receiving chemotherapy for colorectal cancer: impact of patient education before treatment initiation.
abstract: BACKGROUND
  As a consequence of the improved survival due to the availability of several treatment option cost-effectiveness and health-related quality of life (HRQoL) issues have gained increasing attention in colorectal cancer (CRC). In the present study, we aimed to evaluate quality of life, level of anxiety and depression before and after a 6-month follow-up period in chemotherapy receiving patients with CRC.
  
  
  METHODS
  The study was conducted in 50 patients with colon or rectal cancer. All patients were informed and educated about their disease and treatment before getting the treatment and were followed for 6 months, during which they received chemotherapy. A "Questionnaire Form" to collect patient demographic characteristics; the "EORTC QLQ-C30 Scale" and "EQ-5D Scale" to evaluate patient's quality of life; and the "Hospital Anxiety and Depression (HAD) Scale" to evaluate the level of anxiety and depression status of patients, were used as data collecting tools.
  
  
  RESULTS
  Quality of life scores in all functional fields were high in the sixth course when compared to the first according to EORTC QLQ-C30 Scale, reaching to statistically significant level in emotional function score compared to the initial ones (P<0.05). Moreover quality of life score measured in the sixth month with EQ-5D was statistically significantly higher than the initial.
  
  
  CONCLUSIONS
  These data, shows that with proper patient management, quality of life score, and the anxiety and depression levels improve during the course of treatment.
authors.affiliation: 1 Department of Nursing for Internal Medicine, Health Sciences Institute, Gazi University, Beşevler, Ankara, Turkey ; 2 Ambulatory Chemotherapy Unit, Hacettepe University Oncology Hospital, Sıhhiye, Ankara, Turkey ; 3 Department of Nursing for Mental Health and Diseases, Nursing Department, Health Sciences Institute, Gazi University, Beşevler, Ankara, Turkey ; 4 Hacettepe University Oncology Hospital Nursing Services Management, Sıhhiye, Ankara, Turkey ; 5 Department of Medical Oncology, Hacettepe University Institute of Cancer, Department of Medical Oncology, Sıhhiye, Ankara, Turkey.
authors.forename: Ulku
authors.initials: U
authors.lastname: Polat
authors.affiliation: 1 Department of Nursing for Internal Medicine, Health Sciences Institute, Gazi University, Beşevler, Ankara, Turkey ; 2 Ambulatory Chemotherapy Unit, Hacettepe University Oncology Hospital, Sıhhiye, Ankara, Turkey ; 3 Department of Nursing for Mental Health and Diseases, Nursing Department, Health Sciences Institute, Gazi University, Beşevler, Ankara, Turkey ; 4 Hacettepe University Oncology Hospital Nursing Services Management, Sıhhiye, Ankara, Turkey ; 5 Department of Medical Oncology, Hacettepe University Institute of Cancer, Department of Medical Oncology, Sıhhiye, Ankara, Turkey.
authors.forename: Afey
authors.initials: A
authors.lastname: Arpacı
authors.affiliation: 1 Department of Nursing for Internal Medicine, Health Sciences Institute, Gazi University, Beşevler, Ankara, Turkey ; 2 Ambulatory Chemotherapy Unit, Hacettepe University Oncology Hospital, Sıhhiye, Ankara, Turkey ; 3 Department of Nursing for Mental Health and Diseases, Nursing Department, Health Sciences Institute, Gazi University, Beşevler, Ankara, Turkey ; 4 Hacettepe University Oncology Hospital Nursing Services Management, Sıhhiye, Ankara, Turkey ; 5 Department of Medical Oncology, Hacettepe University Institute of Cancer, Department of Medical Oncology, Sıhhiye, Ankara, Turkey.
authors.forename: Satı
authors.initials: S
authors.lastname: Demir
authors.affiliation: 1 Department of Nursing for Internal Medicine, Health Sciences Institute, Gazi University, Beşevler, Ankara, Turkey ; 2 Ambulatory Chemotherapy Unit, Hacettepe University Oncology Hospital, Sıhhiye, Ankara, Turkey ; 3 Department of Nursing for Mental Health and Diseases, Nursing Department, Health Sciences Institute, Gazi University, Beşevler, Ankara, Turkey ; 4 Hacettepe University Oncology Hospital Nursing Services Management, Sıhhiye, Ankara, Turkey ; 5 Department of Medical Oncology, Hacettepe University Institute of Cancer, Department of Medical Oncology, Sıhhiye, Ankara, Turkey.
authors.forename: Sevgi
authors.initials: S
authors.lastname: Erdal
authors.affiliation: 1 Department of Nursing for Internal Medicine, Health Sciences Institute, Gazi University, Beşevler, Ankara, Turkey ; 2 Ambulatory Chemotherapy Unit, Hacettepe University Oncology Hospital, Sıhhiye, Ankara, Turkey ; 3 Department of Nursing for Mental Health and Diseases, Nursing Department, Health Sciences Institute, Gazi University, Beşevler, Ankara, Turkey ; 4 Hacettepe University Oncology Hospital Nursing Services Management, Sıhhiye, Ankara, Turkey ; 5 Department of Medical Oncology, Hacettepe University Institute of Cancer, Department of Medical Oncology, Sıhhiye, Ankara, Turkey.
authors.forename: Suayib
authors.initials: S
authors.lastname: Yalcin
keywords: Education; anxiety; colorectal cancer (CRC); depression; patient; quality of life
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