title: High dengue NS1 antigenemia in febrile patients in Ibadan, Nigeria.
abstract: We conducted a dengue seroprevalence survey among febrile patients positive or negative for malaria in Ibadan, Nigeria. Dengue IgG and NS1 seroprevalence of 73% and 35%, respectively, was observed, and 43% of those with malaria had acute dengue infection (NS1 determination). On the other hand, all participants with malaria were IgG dengue seropositive consistent with the endemicity of both arthropod-borne infections in the region. These data indicate that dengue is emerging as a major and neglected cause of fever in Nigeria.
authors.affiliation: Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria. Electronic address: olufunmilayo.oyero@yahoo.com.
authors.forename: Olufunmilayo G
authors.initials: OG
authors.lastname: Oyero
authors.affiliation: Department of Infectious Diseases/Section of Clinical Virology, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden; Section for Clinical research, Redeem Biomedical System, Douala, Cameroon. Electronic address: jayuk@redeem-biomedical.com.
authors.forename: James A
authors.initials: JA
authors.lastname: Ayukekbong
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood* / Q000276:immunology; D002648:Child; D003715:Dengue / Q000097:blood* / Q000276:immunology / Q000821:virology; D003716:Dengue Virus / Q000145:classification / Q000235:genetics / Q000276:immunology*; D005260:Female; D005334:Fever / Q000097:blood* / Q000276:immunology / Q000821:virology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009549:Nigeria; D017361:Viral Nonstructural Proteins / Q000235:genetics / Q000276:immunology*; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D017361:Viral Nonstructural Proteins
keywords: Dengue virus; Fever; NS1 antigen; Nigeria