title: Analysis of a panel of rapidly growing mycobacteria for resistance to aldehyde-based disinfectants.
abstract: After several accounts across the globe of mycobacteria outbreaks associated with medical procedures and aldehyde disinfectants resistance, we undertook an analysis of mycobacteria isolated from patients seen in a hospital in the United States between 1994 and 2008 to determine prevalence of resistance to aldehyde-based disinfectants. Out of the 117 clinical isolates screened, 6 isolates belonging to the emerging Mycobacterium abscessus group were found to display significant levels of resistance to glutaraldehyde and ortho-phthalaldehyde.
authors.affiliation: Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO.
authors.forename: Mary Ann
authors.initials: MA
authors.lastname: De Groote
authors.affiliation: Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO.
authors.forename: Sara
authors.initials: S
authors.lastname: Gibbs
authors.affiliation: Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO.
authors.forename: Vinicius Calado Nogueira
authors.initials: VC
authors.lastname: de Moura
authors.affiliation: Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO.
authors.forename: Winona
authors.initials: W
authors.lastname: Burgess
authors.affiliation: Division of Infectious Diseases, University of Colorado Denver, Aurora, CO.
authors.forename: Kris
authors.initials: K
authors.lastname: Richardson
authors.affiliation: Department of Medicine, National Jewish Health, Denver, CO.
authors.forename: Shannon
authors.initials: S
authors.lastname: Kasperbauer
authors.affiliation: Division of Infectious Diseases, University of Colorado Denver, Aurora, CO.
authors.forename: Nancy
authors.initials: N
authors.lastname: Madinger
authors.affiliation: Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO. Electronic address: Mary.Jackson@colostate.edu.
authors.forename: Mary
authors.initials: M
authors.lastname: Jackson
mesh_terms: D004202:Disinfectants / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D005976:Glutaral / Q000494:pharmacology*; D006801:Humans; D009165:Mycobacterium Infections, Nontuberculous / Q000382:microbiology; D009170:Nontuberculous Mycobacteria / Q000187:drug effects* / Q000302:isolation & purification; D014481:United States; D009764:o-Phthalaldehyde / Q000494:pharmacology*
chemical_list: D004202:Disinfectants; D009764:o-Phthalaldehyde; D005976:Glutaral
keywords: Glutaraldehyde; Ortho-phthalaldehyde
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