title: A preliminary investigation of the long-term outcome of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders.
abstract: OBJECTIVE
  The aim of this study is to conduct a preliminary examination of long-term outcomes on a broad range of affective disorder symptoms treated with a newly developed intervention: The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP).
  
  
  METHODS
  Maintenance of treatment gains at long-term follow-up (LTFU) were explored in patients (N=15, mean age=32.27; 60% female) who completed a clinical trial of the UP.
  
  
  RESULTS
  Treatment gains observed at 6-month follow-up (6MFU) on measures of clinical severity, general symptoms of depression and anxiety, and a measure of symptom interference in daily functioning were largely maintained 12months later (at an average of 18months posttreatment), and any significant changes from 6MFU to LTFU reflected small increases in symptoms that remained, on average, in the subclinical range.
  
  
  CONCLUSIONS
  These findings provide the first initial support for the durability of broad treatment gains following transdiagnostic treatment.
authors.affiliation: Boston University, 648 Beacon Street, 6th floor, Boston, MA 02215, USA. Electronic address: jbullis@bu.edu.
authors.forename: Jacqueline R
authors.initials: JR
authors.lastname: Bullis
authors.affiliation: Boston University, 648 Beacon Street, 6th floor, Boston, MA 02215, USA. Electronic address: fortunem@bu.edu.
authors.forename: Meghan R
authors.initials: MR
authors.lastname: Fortune
authors.affiliation: Boston University, 648 Beacon Street, 6th floor, Boston, MA 02215, USA. Electronic address: tfarchio@bu.edu.
authors.forename: Todd J
authors.initials: TJ
authors.lastname: Farchione
authors.affiliation: Boston University, 648 Beacon Street, 6th floor, Boston, MA 02215, USA. Electronic address: dhbarlow@bu.edu.
authors.forename: David H
authors.initials: DH
authors.lastname: Barlow
mesh_terms: D000328:Adult; D000342:Affective Symptoms / Q000628:therapy*; D001007:Anxiety / Q000628:therapy*; D002985:Clinical Protocols / Q000592:standards; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003863:Depression / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D012720:Severity of Illness Index; D055815:Young Adult
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