title: Treatment of metastatic extramammary Paget's disease associated with adnexal adenocarcinoma, with anti-HER2 drugs based on genomic alteration ERBB2 S310F.
authors.affiliation: Division of Oncology, Rambam Health Care Campus and Technion-Israel Institute of Technology, Haifa, Israel.
authors.forename: Olga
authors.initials: O
authors.lastname: Vornicova
authors.affiliation: Institute of Pathology, Rambam Health Care Campus and Technion-Israel Institute of Technology, Haifa, Israel.
authors.forename: Dov
authors.initials: D
authors.lastname: Hershkovitz
authors.affiliation: Sharett Institute of Oncology, Hadassah Medical Center, Hebrew University, Jerusalem, Israel.
authors.forename: Tamar
authors.initials: T
authors.lastname: Yablonski-Peretz
authors.affiliation: Institute of Pathology, Rambam Health Care Campus and Technion-Israel Institute of Technology, Haifa, Israel.
authors.forename: Ofer
authors.initials: O
authors.lastname: Ben-Itzhak
authors.affiliation: Department of Nuclear Medicine, Rambam Health Care Campus and Technion-Israel Institute of Technology, Haifa, Israel.
authors.forename: Zohar
authors.initials: Z
authors.lastname: Keidar
authors.affiliation: Division of Oncology, Rambam Health Care Campus and Technion-Israel Institute of Technology, Haifa, Israel.
authors.forename: Gil
authors.initials: G
authors.lastname: Bar-Sela
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D000291:Adnexal Diseases / Q000150:complications / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D005260:Female; D015894:Genome, Human; D006801:Humans; D058990:Molecular Targeted Therapy; D009154:Mutation; D009362:Neoplasm Metastasis; D010145:Paget Disease, Extramammary / Q000150:complications / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000037:antagonists & inhibitors / Q000235:genetics*
chemical_list: D018719:Erb-b2 Receptor Tyrosine Kinases; C508053:ERBB2 protein, human
references.citation: Cancer Discov. 2013 Feb;3(2):224-37
references.pmid: 23220880
references.citation: Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14476-81
references.pmid: 22908275
references.citation: Cancer. 1992 Aug 1;70(3):704-8
references.pmid: 1320453
references.citation: Case Rep Dermatol. 2011 Sep;3(3):223-7
references.pmid: 22135629
references.citation: Nucleic Acids Res. 2011 Jan;39(Database issue):D945-50
references.pmid: 20952405
references.citation: Hum Pathol. 2005 Dec;36(12):1273-80
references.pmid: 16311120
references.citation: J Dermatol. 2009 Aug;36(8):457-61
references.pmid: 19691751
references.citation: J Invest Dermatol. 1999 Aug;113(2):258-62
references.pmid: 10469313
references.citation: J Surg Oncol. 1988 May;38(1):38-44
references.pmid: 2836660