title: Predictor's analysis of anterior circulation cerebral infarction after the endovascular treatment of anterior communicating artery aneurysms.
abstract: BACKGROUND
  Despite increasing acceptance of endovascular coiling for treating anterior communicating artery (ACoA) aneurysms, anterior circulation cerebral infarction (ACI) after embolization remains a limitation. With higher incidence, higher morbidity and higher mortality, it is one of the main factors influencing the ACoA aneurysms prognosis. Determining the risk factors leading to ACI after embolization will have clinical significance. Through retrospective case analysis, this study investigated the risk factors related to ACI after embolization in order to provide information to serve the clinical practice.
  
  
  METHODS
  A retrospective review was performed of patients who had undergone coiling of ACoA aneurysms from 2008 to 2012. All patients had ruptured prior to the completion of embolization. Cases with acute stroke symptoms without alternative diagnoses after embolization were diagnosed as ACI. A total of 32 risk factors such as age, sex, hypertension, diabetes mellitus, modified Fisher grade, Hunt-Hess grade, ventricular hemorrhage, etc. were analyzed using univariate and logistic regression analysis.
  
  
  RESULTS
  Univariate analysis showed that negative fluid volume balance (P = 0.041 <0.05) and modified Fisher grade (P = 0.049 <0.05) reached statistical significance, suggesting that they might be risk factors for ACI after embolization. Multiple logistic regression analysis showed that modified Fisher grade was significantly associated with ACI after embolization, suggesting that it was an independent risk factor (odds ratios (OR): 4.968, 95% confidence intervals (CI): 1.013-24.360, P = 0.048).
  
  
  CONCLUSIONS
  Modified Fisher grade is an independent risk factor for ACI after embolization.
authors.affiliation: Department of Neurological Surgery, Tangshan Gongren Hospital, Tangshan, Hebei Province, People's Republic of China.
authors.forename: Liqian
authors.initials: L
authors.lastname: Sun
authors.affiliation: Department of Ophthalmology, Tangshan Ophthalmology Hospital, Tangshan, Hebei Province, People's Republic of China.
authors.forename: Xiaobin
authors.initials: X
authors.lastname: Jing
authors.affiliation: Department of Neurological Surgery, Tangshan Gongren Hospital, Tangshan, Hebei Province, People's Republic of China.
authors.forename: Changmeng
authors.initials: C
authors.lastname: Cui
authors.affiliation: Department of Neurological Surgery, Tangshan Gongren Hospital, Tangshan, Hebei Province, People's Republic of China.
authors.forename: Jianzhong
authors.initials: J
authors.lastname: Cui
keywords: Anterior circulation cerebral infarction; anterior communicating artery aneurysm; embolization; modified Fisher grade; risk factors
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