title: Behavior therapy for depressed breast cancer patients: predictors of treatment outcome.
abstract: OBJECTIVE
  Major depressive disorder (MDD) is the most common psychiatric disorder among breast cancer patients and is associated with substantial functional impairment. Although several outcome studies have explored the utility of psychotherapy for breast cancer patients with subsyndromal depression symptoms, only a few clinical trials have explored the efficacy of behavior therapy for patients with well-diagnosed MDD. An additional limitation of this research is that little is known about factors that best predict treatment outcome.
  
  
  METHODS
  In the context of a recent randomized trial of behavior activation and problem-solving therapy for depressed breast cancer patients (n = 80; Hopko et al., 2011), this study explored predictors of treatment outcome with selected demographic (age, education, marital status, occupational status), psychosocial (pretreatment depression and environmental reward, coexistent anxiety disorders, social support, history of psychotherapy) and cancer-related variables (cancer stage, duration of cancer diagnosis, and cancer treatment).
  
  
  RESULTS
  Positive treatment outcome as defined by Beck Depression Inventory-II (Beck et al., 1996) response and remission criteria was associated with being married, increased social support, not actively undergoing cancer treatment during psychotherapy, and having a history of psychotherapy.
  
  
  CONCLUSIONS
  The efficacy of behavior therapy for depressed breast cancer patients may depend on several patient variables. Implications for the provision of behavior therapy for breast cancer patients are discussed.
authors.affiliation: Department of Psychology, The University of Tennessee-Knoxville.
authors.forename: Derek Richard
authors.initials: DR
authors.lastname: Hopko
authors.affiliation: Department of Psychology, The University of Tennessee-Knoxville.
authors.forename: Kerry
authors.initials: K
authors.lastname: Cannity
authors.affiliation: Department of Psychology, The University of Tennessee-Knoxville.
authors.forename: Crystal Constance
authors.initials: CC
authors.lastname: McIndoo
authors.affiliation: Department of Psychology, The University of Tennessee-Knoxville.
authors.forename: Audrey Ashton
authors.initials: AA
authors.lastname: File
authors.affiliation: Department of Psychology, The University of Tennessee-Knoxville.
authors.forename: Marlena M
authors.initials: MM
authors.lastname: Ryba
authors.affiliation: Department of Psychology, The University of Tennessee-Knoxville.
authors.forename: Caroline Gray
authors.initials: CG
authors.lastname: Clark
authors.affiliation: The University of Tennessee Medical Center Cancer Institute.
authors.forename: John L
authors.initials: JL
authors.lastname: Bell
mesh_terms: D001521:Behavior Therapy; D001943:Breast Neoplasms / Q000150:complications* / Q000523:psychology*; D003865:Major Depressive Disorder / Q000150:complications* / Q000523:psychology / Q000628:therapy*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010555:Personality Inventory; D011569:Psychiatric Status Rating Scales; D012944:Social Support; D016896:Treatment Outcome