title: The potential role of HPV vaccination in the prevention of infectious complications of pregnancy.
abstract: There is now incontrovertible evidence that HPV is the cause of almost all cases of genital warts, cervical dysplasia and cervical cancer. Moreover the current review of the recent literature on HPV in relation to pregnancy found strong indications that HPV plays an important role in adverse outcomes of pregnancy. HPV may contribute to infertility and may increase the risk of miscarriage. Recent studies indicate a significant rate of vertical transmission of HPV between mother and child but whether the mode of delivery makes a difference to the risk of transmission remains unknown. HPV infection appears to be correlated with both spontaneous preterm birth and preterm prelabor rupture of the membranes.
authors.affiliation: Department of Gynaecology and Obstetrics, Odense University Hospital, Sdr. Boulevard 29, Odense C 5000, Denmark.
authors.forename: Ulla
authors.initials: U
authors.lastname: Bonde
authors.forename: Jan Stener
authors.initials: JS
authors.lastname: Joergensen
authors.forename: Ole
authors.initials: O
authors.lastname: Mogensen
authors.forename: Ronald F
authors.initials: RF
authors.lastname: Lamont
mesh_terms: D000022:Abortion, Spontaneous / Q000517:prevention & control; D005260:Female; D006801:Humans; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control; D030361:Papillomavirus Infections / Q000517:prevention & control* / Q000635:transmission; D053918:Papillomavirus Vaccines / Q000008:administration & dosage* / Q000276:immunology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000517:prevention & control*; D014611:Vaccination / Q000379:methods*
chemical_list: D053918:Papillomavirus Vaccines
keywords: HPV; condylomata acuminata; infertility; miscarriage; pregnancy; pregnancy outcome; preterm birth; preterm prelabour rupture of the membrane; semen