title: Synthesis of optically active deuterated primary amines via reduction of N-tert-butanesulfinyl aldimines.
abstract: Optically active deuterated primary amines have been obtained with 78-98% ee's from chiral N-tert-butanesulfinyl aldimines via reduction with N-Selectride and subsequent alcoholysis.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences , Beijing 100190, China.
authors.forename: Mao
authors.initials: M
authors.lastname: Liu
authors.forename: Ying
authors.initials: Y
authors.lastname: Xie
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Hongjie
authors.initials: H
authors.lastname: Pan
authors.forename: Hua
authors.initials: H
authors.lastname: Tian
authors.forename: Yian
authors.initials: Y
authors.lastname: Shi
mesh_terms: D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D004072:Digitonin / Q000737:chemistry*; D007097:Imines / Q000737:chemistry*; D008239:Lysine / Q000737:chemistry*; D015394:Molecular Structure; D012663:Semicarbazides / Q000737:chemistry*; D013237:Stereoisomerism; D013439:Sulfhydryl Reagents / Q000737:chemistry*; D014633:Valine / Q000737:chemistry*
chemical_list: D000588:Amines; D007097:Imines; D012663:Semicarbazides; D013439:Sulfhydryl Reagents; C042448:aldimine eliminator; D014633:Valine; D008239:Lysine; D004072:Digitonin