title: [The duration of untreated depression is associated with a poor treatment response].
abstract: According to clinical lore the duration of untreated depression is associated with a poor treatment response. This is in accordance with the kindling hypothesis of depression. It is an important subject, since the duration of untreated depression is a potentially modifiable risk factor. Despite this, relatively few studies addressing the problem exist. While an association between the duration of untreated depression and treatment response generally is found, the uncontrolled and often retrospective nature of these studies makes it difficult to ascertain causality.
authors.affiliation: Center for Psykiatrisk Forskning, Aarhus Universitetshospital, Risskov, Skovagervej 2, 8240 Risskov. simon@dadlnet.dk.
authors.forename: Simon
authors.initials: S
authors.lastname: Hjerrild
authors.forename: Poul
authors.initials: P
authors.lastname: Videbech
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use; D003866:Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D017063:Outcome Assessment, Health Care; D011379:Prognosis; D013997:Time Factors; D061665:Time-to-Treatment
chemical_list: D000928:Antidepressive Agents