title: A comparative pathological finding in pigs exposed to fumonisin B1 and/or Mycoplasma hyopneumoniae.
abstract: A more complicated pathology was observed in female pigs infected with Mycoplasma hyopneumoniae, when the same were exposed to 20 ppm dietary levels of fumonisin B1 (FB1) starting 14 days before infection for a period of 42 days as was assessed by gross pathology and pathomorphological examinations or computed tomography, and also manifested by the strong deterioration of the pneumonic process in two pigs and the subsequent euthanizing of one pig. Typical damages in FB1-fed pigs were a strong oedema in the lung and slight oedema in the other internal organs and mild degenerative changes in the kidneys, whereas the typical pathomorphological changes in M. hyopneumoniae-infected pigs corresponded to the morphologic pattern of a catarrhal bronchointerstitial pneumonia more pronounced in the cranial and middle lobes or in the cranial third of the caudal lobe of the lung. The pigs treated by both pathogens (toxic and infectious) revealed strong oedematous changes in the interstitium of lung in addition to deteriorated and extended bronchointerstitial pneumonic process.
authors.affiliation: Faculty of Animal Science, Kaposvár University, Kaposvár, Hungary.
authors.forename: Roland
authors.initials: R
authors.lastname: Pósa
authors.affiliation: Department of General and Clinical Pathology, Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria stoev@uni-sz.bg.
authors.forename: Stoycho
authors.initials: S
authors.lastname: Stoev
authors.affiliation: Faculty of Animal Science, Kaposvár University, Kaposvár, Hungary Research Group of 'Mycotoxins in the Food Chain' of the Hungarian Academy of Sciences and Kaposvár University, Hungary.
authors.forename: Melinda
authors.initials: M
authors.lastname: Kovács
authors.affiliation: Faculty of Animal Science, Kaposvár University, Kaposvár, Hungary.
authors.forename: Tamás
authors.initials: T
authors.lastname: Donkó
authors.affiliation: Faculty of Animal Science, Kaposvár University, Kaposvár, Hungary.
authors.forename: Imre
authors.initials: I
authors.lastname: Repa
authors.affiliation: Centre for Agricultural Research, Hungarian Academy of Sciences, Institute for Veterinary Medical Research, Budapest, Hungary.
authors.forename: Tibor
authors.initials: T
authors.lastname: Magyar
mesh_terms: D000818:Animals; D004487:Edema / Q000139:chemically induced / Q000382:microbiology / Q000473:pathology; D005260:Female; D037341:Fumonisins / Q000633:toxicity*; D008168:Lung / Q000187:drug effects / Q000382:microbiology / Q000473:pathology; D008171:Lung Diseases / Q000139:chemically induced / Q000382:microbiology / Q000473:pathology; D045705:Mycoplasma hyopneumoniae / Q000302:isolation & purification*; D045729:Pneumonia of Swine, Mycoplasmal / Q000382:microbiology / Q000473:pathology*; D013552:Swine / Q000382:microbiology*; D014057:Tomography, X-Ray Computed
chemical_list: D037341:Fumonisins; C056933:fumonisin B1
keywords: Fumonisin B1; Mycoplasma hyopneumoniae; computed tomography; pathology; pigs