title: Molecular markers for breast cancer diagnosis, prognosis and targeted therapy.
abstract: Precision medicine involves understanding the molecular drivers unique to an individual patient's cancer so that specific factors may be targeted with the goal of improved patient outcomes. The purpose of this article is to review standard of care and research grade (non-standard of care) biomarkers in breast cancer that may be useful for diagnosis, prognosis and targeted therapy.
authors.affiliation: University of Southern California Department of Surgery, Division of Breast and Soft Tissue Surgery, Norris Comprehensive Cancer Center, Los Angeles, California.
authors.forename: Julie E
authors.initials: JE
authors.lastname: Lang
authors.forename: Julie S
authors.initials: JS
authors.lastname: Wecsler
authors.forename: Michael F
authors.initials: MF
authors.lastname: Press
authors.forename: Debasish
authors.initials: D
authors.lastname: Tripathy
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000235:genetics*; D001943:Breast Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D005260:Female; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects*; D006801:Humans; D058990:Molecular Targeted Therapy; D011379:Prognosis
chemical_list: D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor
keywords: biomarker; breast cancer; molecular marker; personalized medicine; precision medicine