title: Myocardial serotonin during ischemia under conditions of ischemic preconditioning.
abstract: We studied the dynamics of interstitial serotonin during local myocardial ischemia under conditions of ischemic preconditioning in Wistar rats. Ischemic preconditioning increased serotonin content in the dialysate (p=0.003). During 30-min ischemia, ischemic preconditioning delayed serotonin increase just before the 20th min of ischemia. Ischemic preconditioning promoted short-term increase in the serotonin level in the myocardial interstitium but followed by prolonged ischemia, it delayed the accumulation of serotonin in the myocardial interstitium.
authors.affiliation: Research Institute of Physiology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia, NSE2@mail.ru.
authors.forename: S E
authors.initials: SE
authors.lastname: Naumenko
authors.forename: T V
authors.initials: TV
authors.lastname: Latysheva
authors.forename: M A
authors.initials: MA
authors.lastname: Gilinskii
mesh_terms: D000818:Animals; D015314:Dialysis Solutions / Q000737:chemistry; D019157:Ischemic Preconditioning, Myocardial; D008297:Male; D015428:Myocardial Reperfusion Injury / Q000378:metabolism* / Q000473:pathology / Q000517:prevention & control; D009206:Myocardium / Q000378:metabolism* / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar; D012701:Serotonin / Q000378:metabolism*
chemical_list: D015314:Dialysis Solutions; D012701:Serotonin