title: Exceptionally large mitochondrial fragments to the nucleus in sequenced mollusk genomes.
abstract: The available genome sequences of three mollusks (Biomphalaria glabrata, Aplysia californica and Crassostrea gigas) were first used to investigate the nuclear mitochondrial DNAs (NUMTs) in mollusks. The analysis showed that the NUMT contents were high in B. glabrata (17.738 Kb) and C. gigas (17.192 Kb), of which all or almost all mtDNA sequences were transferred to the nucleus, whereas NUMTs are rare (584 bp) in A. californica. The length of NUMTs was 61 to 5492 bp for B. glabrata, 1711 to 15,481 bp for C. gigas, and 124 to 460 bp for A. californica. The largest C. gigas NUMT covered 84.9% (15,481 bp) of its mitochondrial genome, which is rarely found in invertebrates so far. No correlation was found between NUMT content and genome size in the three sequenced mollusk genomes.
authors.affiliation: a Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences , Qingdao , P.R. China.
authors.forename: Xiujun
authors.initials: X
authors.lastname: Sun
authors.affiliation: a Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences , Qingdao , P.R. China.
authors.forename: Aiguo
authors.initials: A
authors.lastname: Yang
mesh_terms: D000818:Animals; D001482:Base Composition; D002467:Cell Nucleus / Q000235:genetics*; D023061:Gene Order; D059646:Genome Size; D054629:Genome, Mitochondrial; D008928:Mitochondria / Q000235:genetics; D008974:Mollusca / Q000145:classification / Q000235:genetics*; D017422:Sequence Analysis, DNA / Q000379:methods*
keywords: Mitochondrial DNA; NUMT; mollusk