title: Simultaneous determination of galanthamine and lycorine in Lycoris radiata by a capillary electrophoresis with an electrochemiluminescence method.
abstract: A novel capillary electrophoresis with electrochemiluminescence determination method was developed for the determination of two alkaloids based on the electrochemiluminescence signal enhancement effect of the tertiary amine group on tris(2,2'-bipyridyl)ruthenium(II). A linear relationship between the electrochemiluminescence peak area and concentrations of galanthamine and lycorine in the range of 0.07 ∼ 17 μg/mL and 0.07 ∼ 18 μg/mL was obtained and the detection limit was 0.008 and 0.002 μg/mL, respectively. The method is selective, simple, and convenient. It had been successfully applied to the analysis of galanthamine and lycorine in Lycoris radiata samples purchased from a local market.
authors.affiliation: College of Life Science, Northeast Agricultural University, Harbin, China.
authors.forename: Yanchao
authors.initials: Y
authors.lastname: Wang
authors.forename: Guimei
authors.initials: G
authors.lastname: Zhu
authors.forename: Xia
authors.initials: X
authors.lastname: Li
authors.forename: Zaibin
authors.initials: Z
authors.lastname: Hao
mesh_terms: D047151:Amaryllidaceae Alkaloids / Q000032:analysis*; D002021:Buffers; D019075:Electrophoresis, Capillary / Q000379:methods*; D005702:Galantamine / Q000032:analysis*; D006863:Hydrogen-Ion Concentration; D049449:Luminescence; D031426:Lycoris / Q000737:chemistry*; D010617:Phenanthridines / Q000032:analysis*
chemical_list: D047151:Amaryllidaceae Alkaloids; D002021:Buffers; D010617:Phenanthridines; D005702:Galantamine; C015330:lycorine
keywords: Capillary electrophoresis; Electrochemiluminescence; Galanthamine; Lycorine