title: Magnetic resonance imaging of transplanted stem cell fate in stroke.
abstract: Nowadays, scientific findings in the field of regeneration of nervous system have revealed the possibility of stem cell based therapies for damaged brain tissue related disorders like stroke. Furthermore, to achieve desirable outcomes from cellular therapies, one needs to monitor the migration, engraftment, viability, and also functional fate of transplanted stem cells. Magnetic resonance imaging is an extremely versatile technique for this purpose, which has been broadly used to study stroke and assessment of therapeutic role of stem cells. In this review we searched in PubMed search engine by using following keywords; "Stem Cells", "Cell Tracking", "Stroke", "Stem Cell Transplantation", "Nanoparticles", and "Magnetic Resonance Imaging" as entry terms and based on the mentioned key words, the search period was set from 1976 to 2012. The main purpose of this article is describing various advantages of molecular and magnetic resonance imaging of stem cells, with focus on translation of stem cell research to clinical research.
authors.affiliation: cGMP-compliant stem cell facility, Brain and Spinal Cord Injury Research Center, Tarbiat Modares University, Tehran, Iran ; cGMP-compliant stem cell facility, Endocrinology and Metabolism Research Center, Tarbiat Modares University, Tehran, Iran.
authors.forename: Hamid Reza
authors.initials: HR
authors.lastname: Aghayan
authors.affiliation: cGMP-compliant stem cell facility, Brain and Spinal Cord Injury Research Center, Tarbiat Modares University, Tehran, Iran ; Department of Hematology, Faculty of Medicine, Tarbiat Modares University, Tehran, Iran.
authors.forename: Masoud
authors.initials: M
authors.lastname: Soleimani
authors.affiliation: cGMP-compliant stem cell facility, Brain and Spinal Cord Injury Research Center, Tarbiat Modares University, Tehran, Iran ; Cellul Fanavaran Knowledge-Based Organization, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Parisa
authors.initials: P
authors.lastname: Goodarzi
authors.affiliation: cGMP-compliant stem cell facility, Brain and Spinal Cord Injury Research Center, Tarbiat Modares University, Tehran, Iran ; Cellul Fanavaran Knowledge-Based Organization, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Abbas
authors.initials: A
authors.lastname: Norouzi-Javidan
authors.affiliation: cGMP-compliant stem cell facility, Brain and Spinal Cord Injury Research Center, Tarbiat Modares University, Tehran, Iran.
authors.forename: Seyed Hasan
authors.initials: SH
authors.lastname: Emami-Razavi
authors.affiliation: cGMP-compliant stem cell facility, Endocrinology and Metabolism Research Center, Tarbiat Modares University, Tehran, Iran ; Medical Ethics and History of Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Bagher
authors.initials: B
authors.lastname: Larijani
authors.affiliation: cGMP-compliant stem cell facility, Endocrinology and Metabolism Research Center, Tarbiat Modares University, Tehran, Iran ; cGMP-compliant stem cell facility, Brain and Spinal Cord Injury Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Babak
authors.initials: B
authors.lastname: Arjmand
keywords: Cell fate; cell tracking; magnetic resonance imaging; nanoparticle; stem cells; stroke; tracking
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