title: Cronobacter: an emergent pathogen causing meningitis to neonates through their feeds.
abstract: The recognition of Cronobacter as a public health concern was raised when powdered infant formula (PIF) was linked to several neonatal meningitis outbreaks. It is an opportunistic pathogen that causes necrotising enterocolitis, infantile septicaemia, and meningitis which carries a high mortality rate among neonates. It has been also linked with cases of infection in adults and elderly. Over the past decade, much focus has been made on developing sensitive and specific characterisation, detection, and isolation methods to ascertain the quality of foods, notably contamination of PIF with Cronobacter and to understand its ability to cause disease. Whole genome sequencing has unveiled several putative virulence factors, yet the full capacity of the pathogenesis of Cronobacter has not yet been elucidated.
authors.forename: Ben D
authors.initials: BD
authors.lastname: Tall
authors.forename: Yi
authors.initials: Y
authors.lastname: Chen
authors.forename: Qiongqiong
authors.initials: Q
authors.lastname: Yan
authors.forename: Gopal R
authors.initials: GR
authors.lastname: Gopinath
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Grim
authors.forename: Karen G
authors.initials: KG
authors.lastname: Jarvis
authors.forename: Séamus
authors.initials: S
authors.lastname: Fanning
authors.forename: Keith A
authors.initials: KA
authors.lastname: Lampel
mesh_terms: D059126:Cronobacter / Q000302:isolation & purification / Q000472:pathogenicity*; D005516:Food Microbiology; D006801:Humans; D007225:Infant Food; D007231:Infant, Newborn; D016920:Meningitis, Bacterial / Q000382:microbiology*
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