title: Patient-specific flexible and stretchable devices for cardiac diagnostics and therapy.
abstract: Advances in material science techniques and pioneering circuit designs have led to the development of electronic membranes that can form intimate contacts with biological tissues. In this review, we present the range of geometries, sensors, and actuators available for custom configurations of electronic membranes in cardiac applications. Additionally, we highlight the desirable mechanics achieved by such devices that allow the circuits and substrates to deform with the beating heart. These devices unlock opportunities to collect continuous data on the electrical, metabolic, and mechanical state of the heart as well as a platform on which to develop high definition therapeutics.
authors.affiliation: Biomedical Engineering, Washington University in St Louis, USA.
authors.forename: Sarah R
authors.initials: SR
authors.lastname: Gutbrod
authors.affiliation: Biomedical Engineering, Washington University in St Louis, USA.
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Sulkin
authors.affiliation: Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, USA.
authors.forename: John A
authors.initials: JA
authors.lastname: Rogers
authors.affiliation: Biomedical Engineering, Washington University in St Louis, USA. Electronic address: igor@wustl.edu.
authors.forename: Igor R
authors.initials: IR
authors.lastname: Efimov
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis; D018780:Body Surface Potential Mapping / Q000295:instrumentation*; D017147:Defibrillators, Implantable; D055119:Elastic Modulus; D004562:Electrocardiography / Q000295:instrumentation*; D004566:Electrodes; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008567:Membranes, Artificial; D010138:Pacemaker, Artificial
chemical_list: D001672:Biocompatible Materials; D008567:Membranes, Artificial
keywords: Bioelectronics; Imaging; Physiology
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