title: Perspectives in Pediatric Pathology, Chapter 5. Gonadal Dysgenesis.
abstract: One of the most challenging areas in pediatric testicular pathology is the appropriate understanding and pathological diagnosis of disorders of sexual development (DSD), and in particular, the issue of gonadal dysgenesis. Here we present the main concepts necessary for their understanding and appropriate classification, with extensive genetic correlations.
authors.affiliation: 1 Department of Pathology, Hospital La Paz, Universidad Autónoma de Madrid, Calle Arzobispo Morcillo #2, Madrid 28029, Spain.
authors.forename: Manuel
authors.initials: M
authors.lastname: Nistal
authors.affiliation: 2 Department of Cell Biology, Universidad de Alcala, Madrid, Spain.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Paniagua
authors.affiliation: 1 Department of Pathology, Hospital La Paz, Universidad Autónoma de Madrid, Calle Arzobispo Morcillo #2, Madrid 28029, Spain.
authors.forename: Pilar
authors.initials: P
authors.lastname: González-Peramato
authors.affiliation: 3 Department of Pathology, Children's Hospital of Pittsburgh of UPMC, One Children's Hospital Drive, 4401 Penn Avenue, Pittsburgh, PA 15224, USA.
authors.forename: Miguel
authors.initials: M
authors.lastname: Reyes-Múgica
mesh_terms: D001706:Biopsy; D041321:Chromosomes, Human, X; D041322:Chromosomes, Human, Y; D005260:Female; D020022:Genetic Predisposition to Disease; D006059:Gonadal Dysgenesis / Q000145:classification / Q000235:genetics / Q000473:pathology*; D006801:Humans; D008297:Male; D010053:Ovary / Q000473:pathology; D010641:Phenotype; D011237:Predictive Value of Tests; D009626:Terminology as Topic; D013737:Testis / Q000473:pathology*