title: Plasmodium simium/Plasmodium vivax infections in southern brown howler monkeys from the Atlantic Forest.
abstract: Blood infection by the simian parasite, Plasmodium simium, was identified in captive (n = 45, 4.4%) and in wild Alouatta clamitans monkeys (n = 20, 35%) from the Atlantic Forest of southern Brazil. A single malaria infection was symptomatic and the monkey presented clinical and haematological alterations. A high frequency of Plasmodium vivax-specific antibodies was detected among these monkeys, with 87% of the monkeys testing positive against P. vivax antigens. These findings highlight the possibility of malaria as a zoonosis in the remaining Atlantic Forest and its impact on the epidemiology of the disease.
authors.affiliation: Laboratório de Malária, Centro de Pesquisas René Rachou-Fiocruz, Belo Horizonte, MG, Brasil.
authors.forename: Daniela Camargos
authors.initials: DC
authors.lastname: Costa
authors.affiliation: Fundação Universidade Regional de Blumenau, Blumenau, SC, Brasil.
authors.forename: Vanessa Pecini
authors.initials: VP
authors.lastname: da Cunha
authors.affiliation: Laboratório de Malária, Centro de Pesquisas René Rachou-Fiocruz, Belo Horizonte, MG, Brasil.
authors.forename: Gabriela Maria Pereira
authors.initials: GM
authors.lastname: de Assis
authors.affiliation: Fundação Universidade Regional de Blumenau, Blumenau, SC, Brasil.
authors.forename: Júlio César
authors.initials: JC
authors.lastname: de Souza Junior
authors.affiliation: Fundação Universidade Regional de Blumenau, Blumenau, SC, Brasil.
authors.forename: Zelinda Maria Braga
authors.initials: ZM
authors.lastname: Hirano
authors.affiliation: Centro de Pesquisas Aggeu Magalhães-Fiocruz, Recife, PE, Brasil.
authors.forename: Mércia Eliane
authors.initials: ME
authors.lastname: de Arruda
authors.affiliation: Laboratório de Malária, Centro de Pesquisas René Rachou-Fiocruz, Belo Horizonte, MG, Brasil.
authors.forename: Flora Satiko
authors.initials: FS
authors.lastname: Kano
authors.affiliation: Laboratório de Malária, Centro de Pesquisas René Rachou-Fiocruz, Belo Horizonte, MG, Brasil.
authors.forename: Luzia Helena
authors.initials: LH
authors.lastname: Carvalho
authors.affiliation: Laboratório de Malária, Centro de Pesquisas René Rachou-Fiocruz, Belo Horizonte, MG, Brasil.
authors.forename: Cristiana Ferreira Alves
authors.initials: CF
authors.lastname: de Brito
mesh_terms: D000508:Alouatta / Q000469:parasitology*; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D001938:Brazil / Q000453:epidemiology; D065928:Forests; D008288:Malaria / Q000453:epidemiology / Q000469:parasitology / Q000662:veterinary*; D008992:Monkey Diseases / Q000453:epidemiology* / Q000469:parasitology; D010961:Plasmodium / Q000145:classification*; D016133:Polymerase Chain Reaction
chemical_list: D000913:Antibodies, Protozoan
references.citation: Acta Trop. 2006 Nov;100(1-2):54-62
references.pmid: 17126279
references.citation: Bull World Health Organ. 1966;35(5):805-8
references.pmid: 5297817
references.citation: Am J Trop Med Hyg. 1988 Mar;38(2):223-30
references.pmid: 3281486
references.citation: Am J Trop Med Hyg. 1971 Nov;20(6):795-803
references.pmid: 5002245
references.citation: Acta Trop. 2008 Aug;107(2):179-85
references.pmid: 18620330
references.citation: Parasitology. 2004 Dec;129(Pt 6):677-84
references.pmid: 15648690
references.citation: J Clin Microbiol. 1998 Nov;36(11):3378-81
references.pmid: 9774600
references.citation: Rev Saude Publica. 1994 Jun;28(3):192-7
references.pmid: 7747077
references.citation: Infect Immun. 1985 Oct;50(1):58-61
references.pmid: 3899939
references.citation: J Med Primatol. 2006 Apr;35(2):87-96
references.pmid: 16556295
references.citation: J Med Primatol. 2011 Dec;40(6):392-400
references.pmid: 21933192
references.citation: J Clin Microbiol. 2005 May;43(5):2435-40
references.pmid: 15872277
references.citation: Malar J. 2007 Mar 19;6:33
references.pmid: 17371598
references.citation: Mem Inst Oswaldo Cruz. 1951 Mar;49:543-53
references.pmid: 14890537
references.citation: Mem Inst Oswaldo Cruz. 1997 Mar-Apr;92(2):235-43
references.pmid: 9332584
references.citation: Trop Med Int Health. 2012 Aug;17(8):989-1000
references.pmid: 22643072
references.citation: J Parasitol. 1969 Aug;55(4):814-6
references.pmid: 4390413
references.citation: Rev Inst Med Trop Sao Paulo. 1968 Sep-Oct;10(5):287-8
references.pmid: 4974015
references.citation: Mol Biochem Parasitol. 1993 Apr;58(2):283-92
references.pmid: 8479452
references.citation: Malar J. 2007 Sep 19;6:127
references.pmid: 17880709
references.citation: Mem Inst Oswaldo Cruz. 1992;87 Suppl 3:1-20
references.pmid: 1343676