title: Post-operative radiotherapy for the treatment of malignant solitary fibrous tumor of the nasal and paranasal area.
abstract: OBJECTIVE
  Solitary fibrous tumor is a rare tumor occurring in almost every anatomic location of human body; however, reports of malignant solitary fibrous tumor in the nasal and paranasal area are especially rare. In this report, we describe a case of non-recurrent malignant solitary fibrous tumor of the nasal and paranasal area.
  
  
  METHODS
  The patient was initially treated with nasal and paranasal tumor cytoreductive surgery, followed by post-operative three-dimensional conformal intensity modulated radiation therapy (dynamic MLC Varian 600CD Linac, inversely optimized by the Eclipse system) and stereotactic body radiation therapy to provide a radical cure for residual tumor.
  
  
  RESULTS
  The tumor of the nasal and paranasal area was effectively treated and the integrity of the right eye kept. There were no signs of recurrence after four and a half years of further follow-up.
  
  
  CONCLUSIONS
  This is the first attempt to successfully combine cytoreductive surgery with intensity modulated radiation therapy and stereotactic body radiation therapy together to treat solitary fibrous tumor of the nasal and paranasal area, which may provide a potential strategy for the treatment of similar cases.
authors.affiliation: Department of Radiation Oncology, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Xue
authors.affiliation: Department of Radiation Oncology, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
authors.forename: Guangjin
authors.initials: G
authors.lastname: Chai
authors.affiliation: Department of Radiation Oncology, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Xiao
authors.affiliation: Department of Radiation Oncology, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Wang
authors.affiliation: Department of Radiation Oncology, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
authors.forename: Yunfeng
authors.initials: Y
authors.lastname: Mu
authors.affiliation: Department of Radiation Oncology, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
authors.forename: Yujie
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Radiation Oncology, Xijing Hospital, The Fourth Military Medical University, Xi'an, China meishi_xa@163.com.
authors.forename: Mei
authors.initials: M
authors.lastname: Shi
mesh_terms: D000293:Adolescent; D002681:China; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D011184:Postoperative Period; D016634:Radiosurgery; D018714:Radiotherapy, Adjuvant; D050397:Radiotherapy, Intensity-Modulated; D054364:Solitary Fibrous Tumors / Q000000981:diagnostic imaging / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: radiotherapy; solitary fibrous tumor