title: Body Mass Index Is Associated with Hypercholesterolemia following Thyroid Hormone Withdrawal in Thyroidectomized Patients.
abstract: Thyroid hormone withdrawal (THW) for postoperative radioiodine adjuvant therapy or diagnostic radioiodine whole body scan in patients with differentiated thyroid cancers results in acute thyroid hormone deficiency and abnormal lipid profiles. To better clarify the clinical pattern of dyslipidemia occurring after THW, we retrospectively analyzed the association between serum total cholesterol level after THW and various clinical factors in a total of 61 patients who underwent total thyroidectomy due to papillary thyroid cancers from January 2010 to March 2012, in Severance Hospital, Seoul, Korea. Preoperative baseline total cholesterol was significantly correlated with post-THW total cholesterol level; however, age, gender, or elevated TSH level after THW itself was not correlated with post-THW total cholesterol level. A significant correlation between preoperative measured BMI and post-THW total cholesterol level was found (r = 0.263, P = 0.041). In multiple logistic analysis, BMI was an independent determining factor of post-THW total cholesterol level (P = 0.012).
authors.affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea ; Department of Medicine, The Graduate School, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea.
authors.forename: Dong Yeob
authors.initials: DY
authors.lastname: Shin
authors.affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea ; Severance Executive Healthcare Clinic, Yonsei University Health System, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea ; Severance Check-up, Yonsei University Health System, 10 Tongil-ro, Jung-gu, Seoul 100-753, Republic of Korea.
authors.forename: Kwang Joon
authors.initials: KJ
authors.lastname: Kim
authors.affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea ; Department of Medicine, The Graduate School, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea.
authors.forename: Yongin
authors.identifier: 0000-0002-4645-816X
authors.initials: Y
authors.lastname: Cho
authors.affiliation: Department of Endocrinology and Metabolism, National Health Insurance Service, Ilsan Hospital, Goyang, Gyeonggi 410-719, Republic of Korea.
authors.forename: Kyeong Hye
authors.identifier: 0000-0001-5190-2213
authors.initials: KH
authors.lastname: Park
authors.affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea ; Department of Medicine, The Graduate School, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea.
authors.forename: Sena
authors.initials: S
authors.lastname: Hwang
authors.affiliation: Department of Surgery, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea.
authors.forename: Woong Youn
authors.initials: WY
authors.lastname: Chung
authors.affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea.
authors.forename: Eun Jig
authors.initials: EJ
authors.lastname: Lee
references.citation: Lancet. 2004 Jan 10;363(9403):157-63
references.pmid: 14726171
references.citation: Clin Endocrinol (Oxf). 2003 Nov;59(5):607-12
references.pmid: 14616885
references.citation: Clin Endocrinol (Oxf). 2009 Jan;70(1):152-60
references.pmid: 18494864
references.citation: Thyroid. 2008 Aug;18(8):825-30
references.pmid: 18651824
references.citation: Endocr J. 2009;56(6):753-8
references.pmid: 19506325
references.citation: J Clin Endocrinol Metab. 2001 Mar;86(3):1206-11
references.pmid: 11238510
references.citation: Clin Endocrinol (Oxf). 2013 Sep;79(3):416-23
references.pmid: 23278171
references.citation: Atherosclerosis. 2011 Sep;218(1):77-82
references.pmid: 21605865
references.citation: J Clin Endocrinol Metab. 1998 Jan;83(1):140-3
references.pmid: 9435431
references.citation: J Clin Endocrinol Metab. 2005 Sep;90(9):5317-20
references.pmid: 15985488
references.citation: Endocr Res. 2000 Feb;26(1):1-21
references.pmid: 10711719
references.citation: Yonsei Med J. 2010 Jul;51(4):492-8
references.pmid: 20499412
references.citation: Eur J Endocrinol. 2012 Dec 10;168(1):59-65
references.pmid: 23093697
references.citation: N Engl J Med. 2006 Aug 24;355(8):779-87
references.pmid: 16926276
references.citation: Clin Endocrinol (Oxf). 2009 Jul;71(1):130-6
references.pmid: 19178521
references.citation: J Biol Chem. 2003 Sep 5;278(36):34114-8
references.pmid: 12829694
references.citation: Atherosclerosis. 2009 Jun;204(2):e77-81
references.pmid: 18977482
references.citation: Minerva Endocrinol. 2006 Jun;31(2):173-8
references.pmid: 16682940
references.citation: J Clin Endocrinol Metab. 1988 Jan;66(1):51-6
references.pmid: 3335609
references.citation: Arch Intern Med. 2000 Feb 28;160(4):526-34
references.pmid: 10695693
references.citation: Mayo Clin Proc. 1993 Sep;68(9):860-6
references.pmid: 8371604
references.citation: Thyroid. 2009 Jan;19(1):13-20
references.pmid: 19072673
references.citation: Clin Chem. 1972 Jun;18(6):499-502
references.pmid: 4337382
references.citation: J Endocrinol Invest. 2011 Jul-Aug;34(7):488-92
references.pmid: 20651468
references.citation: J Clin Endocrinol Metab. 2012 Aug;97(8):2724-31
references.pmid: 22730515
references.citation: Thyroid. 2009 Nov;19(11):1167-214
references.pmid: 19860577
references.citation: J Endocrinol Invest. 2006 Jan;29(1):32-40
references.pmid: 16553031
references.citation: Q J Med. 1986 May;59(229):513-21
references.pmid: 3763814
references.citation: Exp Clin Endocrinol Diabetes. 2010 Jun;118(6):381-7
references.pmid: 19658059
references.citation: J Clin Endocrinol Metab. 2012 Feb;97(2):326-33
references.pmid: 22205712
references.citation: Thyroid. 2012 Nov;22(11):1096-103
references.pmid: 23050788