title: Designing two-photon fluorescent probes based on the target-induced enhancement of the absorption cross-section.
abstract: We have reported a new strategy to design two-photon (2P) fluorescent probes for simultaneous elevation of the 2P absorption cross-section (δ) and quantum yield (ϕ). The target-induced hydrogen bond-chelated ring enhances molecular planarity, leading to the enhancement of δ; meanwhile, the photo-induced electron transfer (PET) "on-off" process modulates ϕ.
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China. zhhliu@whu.edu.cn.
authors.forename: Lingyu
authors.initials: L
authors.lastname: Zeng
authors.forename: Shiyu
authors.initials: S
authors.lastname: Chen
authors.forename: Tian
authors.initials: T
authors.lastname: Xia
authors.forename: Cheng
authors.initials: C
authors.lastname: Zhong
authors.forename: Zhihong
authors.initials: Z
authors.lastname: Liu
mesh_terms: D065966:Absorption, Physicochemical; D005456:Fluorescent Dyes / Q000737:chemistry*; D015394:Molecular Structure; D017785:Photons
chemical_list: D005456:Fluorescent Dyes