title: MicroRNAs: novel players in cancer diagnosis and therapies.
abstract: First discovered in 1993, microRNAs (miRNAs) have been one of the hottest research areas over the past two decades. Oftentimes, miRNAs levels are found to be dysregulated in cancer patients. The potential use of miRNAs in cancer therapies is an emerging and promising field, with research finding miRNAs to play a role in cancer initiation, tumor growth, and metastasis. Therefore, miRNAs could become an integral part from cancer diagnosis to treatment in future. This review aims to examine current novel research work on the potential roles of miRNAs in cancer therapies, while also discussing several current challenges and needed future research.
authors.affiliation: Department of Physiology, Michigan State University, East Lansing, MI 48824, USA.
authors.forename: Aaron L
authors.identifier: 0000-0003-3300-0333
authors.initials: AL
authors.lastname: Oom
authors.affiliation: Department of Physiology, Michigan State University, East Lansing, MI 48824, USA ; Cellular and Molecular Biology Graduate Program, Michigan State University, East Lansing, MI 48824, USA.
authors.forename: Brock A
authors.initials: BA
authors.lastname: Humphries
authors.affiliation: Department of Physiology, Michigan State University, East Lansing, MI 48824, USA ; Cellular and Molecular Biology Graduate Program, Michigan State University, East Lansing, MI 48824, USA ; Center for Integrative Toxicology, Michigan State University, East Lansing, MI 48824, USA.
authors.forename: Chengfeng
authors.identifier: 0000-0002-2196-6854
authors.initials: C
authors.lastname: Yang
mesh_terms: D014408:Biomarkers, Tumor / Q000096:biosynthesis* / Q000235:genetics; D019008:Drug Resistance, Neoplasm / Q000235:genetics; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D035683:MicroRNAs / Q000096:biosynthesis* / Q000235:genetics; D058990:Molecular Targeted Therapy; D009369:Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy
chemical_list: D014408:Biomarkers, Tumor; D035683:MicroRNAs
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