title: Tick-borne lymphadenopathy, an emerging disease.
abstract: Tick-borne lymphadenopathy (TIBOLA) is a spotted fever group disease characterized by an eschar and pronounced enlarged lymph nodes after a scalp tick bite. The goal of this synopsis is to review the TIBOLA literature published until May 2013: Forty-one articles (reporting 537 cases) were included. There was a predominance of cases in females and young people. Spain, France, and Hungary reported the majority of cases, and they were mainly reported in the colder seasons. The involved tick bite was frequently on the scalp. Rickettsia slovaca was the most frequent identified bacterium and Dermacentor marginatus the most frequently identified vector. The most prescribed antibiotic was doxycycline. TIBOLA has the potential to emerge outside Europe: improving knowledge of TIBOLA may promote early symptoms recognition and may allow early treatment.
authors.affiliation: Centro Hospitalar São João, Porto, Portugal; Faculdade de Medicina da Universidade do Porto, Porto, Portugal. Electronic address: pintoandre@gmail.com.
authors.forename: André
authors.initials: A
authors.lastname: Silva-Pinto
authors.affiliation: Centro Hospitalar São João, Porto, Portugal; Faculdade de Medicina da Universidade do Porto, Porto, Portugal.
authors.forename: Maria de Lurdes
authors.initials: Mde L
authors.lastname: Santos
authors.affiliation: Centro Hospitalar São João, Porto, Portugal; Faculdade de Medicina da Universidade do Porto, Porto, Portugal.
authors.forename: António
authors.initials: A
authors.lastname: Sarmento
mesh_terms: D000818:Animals; D005260:Female; D006801:Humans; D008206:Lymphatic Diseases / Q000453:epidemiology* / Q000382:microbiology; D008297:Male; D012281:Rickettsia / Q000302:isolation & purification / Q000502:physiology; D017282:Tick-Borne Diseases / Q000453:epidemiology* / Q000382:microbiology; D013987:Ticks / Q000382:microbiology
keywords: DEBONEL; Rickettsia infections (MeSH); Rickettsia raoultii; Rickettsia slovaca; TIBOLA