title: Enzyme immobilised novel core-shell superparamagnetic nanocomposites for enantioselective formation of 4-(R)-hydroxycyclopent-2-en-1-(S)-acetate.
abstract: Lipase immobilized novel high surface area core-shell superparamagnetic nanoparticles have been fabricated and used as efficient reusable catalysts for the selective production of pharmaceutically important chiral isomers from meso-cyclopent-2-en-1,4-diacetate.
authors.affiliation: Centre for Materials Science, School of Forensic and Investigative Sciences, University of Central Lancashire, Preston, PR1 2HE, UK. tsen@uclan.ac.uk.
authors.forename: Maneea Eizadi
authors.initials: ME
authors.lastname: Sharifabad
authors.forename: Ben
authors.initials: B
authors.lastname: Hodgson
authors.forename: Mourad
authors.initials: M
authors.lastname: Jellite
authors.forename: Tim
authors.initials: T
authors.lastname: Mercer
authors.forename: Tapas
authors.initials: T
authors.lastname: Sen
mesh_terms: D000085:Acetates / Q000737:chemistry / Q000378:metabolism*; D055162:Biocatalysis; D003517:Cyclopentanes / Q000737:chemistry / Q000378:metabolism*; D004800:Enzymes, Immobilized / Q000737:chemistry / Q000378:metabolism*; D008049:Lipase / Q000737:chemistry / Q000378:metabolism*; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D008968:Molecular Conformation; D010316:Particle Size; D013237:Stereoisomerism
chemical_list: D000085:Acetates; D003517:Cyclopentanes; D004800:Enzymes, Immobilized; D058185:Magnetite Nanoparticles; D008049:Lipase