title: Update on colon cancer screening: recent advances and observations in colorectal cancer screening.
abstract: There have been many recent advances and observations regarding colorectal cancer (CRC) screening. New CRC surveillance guidelines have been published to help endoscopists with the management of important clinical issues such as serrated polyps. There have been several important large studies examining the impact of endoscopic process measures such as bowel prep, withdrawal time, and adenoma detection rate on CRC screening. In addition, there have been technical advances in CT colonography including the development of exams that do not require a bowel preparation. Other new technology such as colon capsule endoscopy may aid endoscopists in the challenge of completing the evaluation of the colon in those patients with an incomplete colonoscopy. Finally, there have been large studies which examine the performance characteristics of the so-called non-invasive CRC screening tests such as fecal immunochemical test (FIT) and fecal DNA.
authors.affiliation: Department of Veterans Affairs Medical Center, 215 North Main Street, White River Junction, VT, 05009, USA, joseph.anderson@dartmouth.edu.
authors.forename: Joseph C
authors.initials: JC
authors.lastname: Anderson
authors.forename: Robert D
authors.initials: RD
authors.lastname: Shaw
mesh_terms: D000236:Adenoma / Q000175:diagnosis*; D053704:Capsule Endoscopy; D002277:Carcinoma / Q000175:diagnosis*; D023881:Colonography, Computed Tomographic; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000175:diagnosis*; D055088:Early Detection of Cancer / Q000379:methods*; D006801:Humans
references.citation: Am J Gastroenterol. 2010 Sep;105(9):2017-25
references.pmid: 20502450
references.citation: Am J Gastroenterol. 2012 Sep;107(9):1315-29; quiz 1314, 1330
references.pmid: 22710576
references.citation: Gastrointest Endosc. 2014 Feb;79(2):307-16
references.pmid: 24060522
references.citation: Br Med Bull. 1971 Jan;27(1):3-8
references.pmid: 5100948
references.citation: Am J Gastroenterol. 2014 Feb;109(2):148-54
references.pmid: 24496417
references.citation: CA Cancer J Clin. 2006 May-Jun;56(3):143-59; quiz 184-5
references.pmid: 16737947
references.citation: AJR Am J Roentgenol. 2013 Oct;201(4):787-94
references.pmid: 24059367
references.citation: Gastroenterology. 2013 Jan;144(1):74-80.e1
references.pmid: 23022496
references.citation: Gastrointest Endosc. 2012 Nov;76(5):1003-8
references.pmid: 23078924
references.citation: Gastrointest Endosc. 2003 Jul;58(1):76-9
references.pmid: 12838225
references.citation: Expert Rev Gastroenterol Hepatol. 2014 Mar;8(3):211-3
references.pmid: 24490683
references.citation: Clin Gastroenterol Hepatol. 2013 May;11(5):541-2
references.pmid: 23246647
references.citation: Eur Radiol. 2012 Jul;22(7):1488-94
references.pmid: 22210409
references.citation: Gastrointest Endosc. 2014 Sep;80(3):463-70
references.pmid: 24818550
references.citation: N Engl J Med. 2008 Sep 18;359(12):1207-17
references.pmid: 18799557
references.citation: Hum Mutat. 2013 Mar;34(3):490-7
references.pmid: 23255516
references.citation: Gastroenterology. 2009 Feb;136(2):459-70
references.pmid: 19026650
references.citation: CA Cancer J Clin. 2014 Mar-Apr;64(2):104-17
references.pmid: 24639052
references.citation: Gastrointest Endosc. 2012 Mar;75(3):545-53
references.pmid: 22138085
references.citation: Gastrointest Endosc. 2013 Apr;77(4):617-23
references.pmid: 23321338
references.citation: Gut. 2012 Nov;61(11):1552-9
references.pmid: 22198714
references.citation: Gastrointest Endosc. 2011 Jun;73(6):1207-14
references.pmid: 21481857
references.citation: N Engl J Med. 2007 Oct 4;357(14):1403-12
references.pmid: 17914041
references.citation: Clin Chem. 2003 Jul;49(7):1185-7
references.pmid: 12816918
references.citation: Ann Intern Med. 2014 Feb 4;160(3):171
references.pmid: 24658694
references.citation: Gastroenterology. 2012 Feb;142(2):248-56; quiz e25-6
references.pmid: 22062357
references.citation: Lancet. 2002 Feb 2;359(9304):403-4
references.pmid: 11844514
references.citation: N Engl J Med. 2009 Jun 25;360(26):2699-701
references.pmid: 19474419
references.citation: Gastroenterology. 2012 Sep;143(3):844-857
references.pmid: 22763141
references.citation: Am J Gastroenterol. 2014 Mar;109(3):417-26
references.pmid: 24394752
references.citation: Gastrointest Endosc. 2012 Mar;75(3):515-20
references.pmid: 22018551
references.citation: N Engl J Med. 2014 Apr 3;370(14):1350-1
references.pmid: 24645801
references.citation: Clin Gastroenterol Hepatol. 2014 Jul;12(7):1119-26
references.pmid: 24333512
references.citation: Clin Gastroenterol Hepatol. 2010 Jun;8(6):516-22
references.pmid: 20215066
references.citation: Radiology. 2014 Mar;270(3):784-90
references.pmid: 24475809
references.citation: Diagn Mol Pathol. 2005 Sep;14(3):183-91
references.pmid: 16106201
references.citation: Clin Gastroenterol Hepatol. 2012 Jun;10(6):633-8
references.pmid: 22426085
references.citation: Hum Pathol. 2000 Jan;31(1):51-7
references.pmid: 10665913
references.citation: Am J Gastroenterol. 2009 Mar;104(3):739-50
references.pmid: 19240699
references.citation: Gastrointest Endosc. 2010 Apr;71(4):792-8
references.pmid: 20363421
references.citation: Gut. 2013 Feb;62(2):272-9
references.pmid: 22345660
references.citation: Am J Gastroenterol. 2014 Feb;109(2):183-9
references.pmid: 24343549
references.citation: Pharmacogenomics. 2007 Jun;8(6):597-608
references.pmid: 17559349
references.citation: Gastrointest Endosc. 2013 Sep;78(3):444-9
references.pmid: 23948194
references.citation: Clin Chem. 2012 Feb;58(2):375-83
references.pmid: 22194633
references.citation: Gastrointest Endosc. 2013 Dec;78(6):805-815
references.pmid: 24119509
references.citation: AJR Am J Roentgenol. 2012 Jul;199(1):W27-34
references.pmid: 22733929
references.citation: Gastrointest Endosc. 2011 Jun;73(6):1240-5
references.pmid: 21628016
references.citation: J Med Genet. 2013 Dec;50(12):785-93
references.pmid: 23956446
references.citation: JAMA. 2006 Sep 27;296(12):1479-87
references.pmid: 17003396
references.citation: N Engl J Med. 2014 Apr 3;370(14):1287-97
references.pmid: 24645800
references.citation: Clin Gastroenterol Hepatol. 2014 Aug;12(8):1303-10
references.pmid: 24398064
references.citation: N Engl J Med. 2004 Dec 23;351(26):2704-14
references.pmid: 15616205
references.citation: Clin Gastroenterol Hepatol. 2013 Oct;11(10):1308-12
references.pmid: 23660415
references.citation: Gastroenterology. 2008 Aug;135(2):489-98
references.pmid: 18602395
references.citation: Clin Gastroenterol Hepatol. 2011 Jan;9(1):42-6
references.pmid: 20888435
references.citation: J Am Coll Radiol. 2013 Jan;10(1):30-6
references.pmid: 23290671
references.citation: N Engl J Med. 2012 Feb 23;366(8):697-706
references.pmid: 22356323
references.citation: N Engl J Med. 2014 Apr 3;370(14):1298-306
references.pmid: 24693890
references.citation: Clin Gastroenterol Hepatol. 2013 May;11(5):534-40.e1
references.pmid: 23078891
references.citation: N Engl J Med. 2003 Dec 4;349(23):2191-200
references.pmid: 14657426
references.citation: Lancet Oncol. 2012 Jan;13(1):55-64
references.pmid: 22088831
references.citation: N Engl J Med. 2010 May 13;362(19):1795-803
references.pmid: 20463339
references.citation: CA Cancer J Clin. 2008 May-Jun;58(3):130-60
references.pmid: 18322143