title: [Study on prevention effect of huoluotongnao tablet on stroke (II)].
abstract: OBJECTIVE
  To study the prevention effect of Huoluotongnao tablet on stroke.
  
  
  METHODS
  Bilateral common carotid artery ligation and reperfusion injury model and reperfusion injury in focal cerebral ischemia-induced thrombosis line method rat model were used.
  
  
  RESULTS
  Huoluotongnao tablet could significantly reduce the pathological injury of rat brain tissue changes of these two models, and increase the activity of SOD and decrease the content of MDA in the brain tissue and plasma of rats. The brain water content of treatment groups were significantly reduced. The behavioral index and cerebral infarction range index were effectively improved in the middle cerebral artery occlusion reperfusion model rats.
  
  
  CONCLUSIONS
  Huoluotongnao tablet has certain prevention effect on stroke.
authors.forename: Ren-Qiang
authors.initials: RQ
authors.lastname: Ma
authors.forename: Yi-Hu
authors.initials: YH
authors.lastname: Ma
authors.forename: Pei-Qing
authors.initials: PQ
authors.lastname: Liu
mesh_terms: D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D002545:Brain Ischemia / Q000378:metabolism / Q000517:prevention & control*; D004195:Disease Models, Animal; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D020244:Infarction, Middle Cerebral Artery / Q000378:metabolism / Q000517:prevention & control; D008297:Male; D008315:Malondialdehyde / Q000097:blood / Q000378:metabolism; D018696:Neuroprotective Agents / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D015427:Reperfusion Injury / Q000378:metabolism / Q000517:prevention & control*; D013482:Superoxide Dismutase / Q000097:blood / Q000378:metabolism; D013607:Tablets
chemical_list: D004365:Drugs, Chinese Herbal; D018696:Neuroprotective Agents; D013607:Tablets; D008315:Malondialdehyde; D013482:Superoxide Dismutase