title: The role of decision-making ability in HIV/AIDS: impact on prospective memory.
abstract: BACKGROUND
  Prospective memory (ProM), a form of episodic memory related to execution of future intentions, is important for everyday functioning. Among persons living with HIV (PLWH), executive dysfunction is implicated in ProM impairments. However, specific subcomponents of executive functioning involved in ProM deficits remain poorly understood. Unlike more "traditional" neurocognitive (NC) measures of executive functioning associated with dorsolateral prefrontal cortex (i.e., conceptual reasoning, abstraction), those associated with medial orbitofrontal/ventromedial prefrontal (mOF/vmP) cortex (i.e., decision making, inhibitory control, goal-oriented behavior) have yet to be examined in ProM.
  
  
  METHODS
  This study characterized ProM ability in a sample of 89 HIV-seropositive adults and examined the unique role of decision-making ability in ProM. Participants completed a standard NC battery, the Iowa Gambling Task (IGT; a decision-making measure), and the Memory for Intentions Screening Test (MIST; a ProM measure).
  
  
  RESULTS
  Correlational analyses revealed that both traditional executive functioning measures and the IGT were associated with ProM. Regression analyses revealed that the IGT significantly predicted ProM, even after accounting for NC measures. Among all NC measures, only executive functioning significantly contributed to ProM.
  
  
  CONCLUSIONS
  Further examination of mOF/vmP-sensitive executive dysfunction within this population is needed as PLWH may require more tailored treatment recommendations due to specific decision-making difficulties that can impact medication management.
authors.affiliation: a Department of Psychology , Fordham University , Bronx , NY , USA.
authors.forename: Kelly
authors.initials: K
authors.lastname: Coulehan
authors.forename: Desiree
authors.initials: D
authors.lastname: Byrd
authors.forename: Alyssa
authors.initials: A
authors.lastname: Arentoft
authors.forename: Jennifer
authors.initials: J
authors.lastname: Monzones
authors.forename: Armando
authors.initials: A
authors.lastname: Fuentes
authors.forename: Felicia
authors.initials: F
authors.lastname: Fraser
authors.forename: Ana
authors.initials: A
authors.lastname: Rosario
authors.forename: Susan
authors.initials: S
authors.lastname: Morgello
authors.forename: Monica Rivera
authors.initials: MR
authors.lastname: Mindt
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000503:physiopathology*; D000328:Adult; D003657:Decision Making / Q000502:physiology*; D056344:Executive Function / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D061212:Memory, Episodic; D008875:Middle Aged
keywords: Decision making; Executive function; HIV/AIDS; Neurocognition; Prospective memory
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