title: Odontogenic myxofibroma: a concise review of the literature with emphasis on the surgical approach.
abstract: OBJECTIVE
  The aim of this work is to report a review of the literature concerning epidemiology, clinical and radiographic features as well as treatment of odontogenic myxofibroma (MF).
  
  
  METHODS
  The PubMed database was searched using the following keywords: "odontogenic myxofibroma", "odontogenic fibromyxoma", "myxofibroma of the jaw" and "fibromyxoma of the jaw".
  
  
  RESULTS
  Fifteen articles reporting the experience with 24 patients were identified. Male/female ratio was 1:1.4 and the average age 29.5 years. The most frequent location was the mandible. In 66.7% of the cases the radiographic appearance was a multilocular radiolucency. Swelling was observed in 13 patients (92.86%), varying degrees of pain in 5 (35.71%) and paresthesia in only one patient (7.14%). Six out of 24 patients (26.09%) were treated with radical surgery and 17 out of 24 (73.91%) with a conservative approach. In two out of 21 cases (9.52%) a recurrence was reported.
  
  
  CONCLUSIONS
  MF is an extremely rare tumour and no agreement exist on the causes of its development. According to the present review, the choice of treatment should depend on variables such as localization, presence of a primary or of a recurrent lesion, age, general medical conditions and aesthetic needs of the patient.
authors.affiliation: Center of Oral Laser Surgery and Oral Pathology, Dental School. Department of Biomedical, Biotechnological and Translational Sciences, Via Gramsci, 14, 43100 Parma, Italy, marco.meleti@unipr.it.
authors.forename: Marco
authors.initials: M
authors.lastname: Meleti
authors.forename: Ilaria
authors.initials: I
authors.lastname: Giovannacci
authors.forename: Domenico
authors.initials: D
authors.lastname: Corradi
authors.forename: Maddalena
authors.initials: M
authors.lastname: Manfredi
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Merigo
authors.forename: Mauro
authors.initials: M
authors.lastname: Bonanini
authors.forename: Paolo
authors.initials: P
authors.lastname: Vescovi
mesh_terms: D000328:Adult; D005260:Female; D005350:Fibroma / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*; D006801:Humans; D007573:Jaw Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*; D008297:Male; D009808:Odontogenic Tumors / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*