title: Topical vs Combination Ciprofloxacin in the Management of Discharging Chronic Suppurative Otitis Media.
abstract: OBJECTIVE
  To study the microbial flora and determine the efficacy of topical ciprofloxacin ear drops in comparison with combination of topical and oral ciprofloxacin as first line management in patients diagnosed with chronic suppurative otitis media.
  
  
  METHODS
  Prospective randomized interventional clinical trial on 100 patients who presented with an acute episode of CSOM to our outpatient department.
  
  
  RESULTS
  In our study, topical ciprofloxacin therapy was found to be an effective treatment for an acute on chronic otitis media as was the combination therapy though the overall recurrence rate was found to be more in the former group.
  
  
  CONCLUSIONS
  In the absence of systemic infection or serious underlying disease, topical antibiotics alone constitute first line treatment for most patients with chronic suppurative otitis media, finding no evidence that systemic antibiotics alone or in combination with topical preparations improve treatment outcomes compared with topical antibiotics alone.
authors.affiliation: Professor & Unit Chief, Department of Otorhinolaryngology, J.J.M. Medical College, Davangere , Karnataka, India .
authors.forename: G S
authors.initials: GS
authors.lastname: Renukananda
authors.affiliation: Professor, Department of Otorhinolaryngology, J.J.M. Medical College, Davangere , Karnataka, India .
authors.forename: Santosh
authors.initials: S
authors.lastname: U P
authors.affiliation: Postgraduate, Department of Otorhinolaryngology, J.J.M. Medical College, Davangere , Karnataka, India .
authors.forename: Nitha Mary
authors.initials: NM
authors.lastname: George
keywords: Antibiotic resistance; Chronic suppurative otitis media; Ciprofloxacin