title: [Micropump infusion of gonadorelin in the treatment of hypogonadotropic hypogonadism in patients with pituitary stalk interruption syndrome: cases analysis and literature review].
abstract: Two cases of hypogonadotropic hypogonadism caused by pituitary stalk interruption syndrome treated by pulse infusion of gonadorelin via micropump were reported, and their clinical features and the treatment process of pulse infusion of gonadorelin via micropump summarized. Both of the 2 patients were presented primarily with hypogonadotropic hypogonadism. After the treatment with pulse infusion of gonadorelin via micropump, their syndrome of androgen deficiency improved and the gonadotropin levels promoted at the end of 12 weeks' follow-up. Pulse infusion of gonadorelin via micropump is an alternative to treat hypogonadotropic hypogonadism caused by pituitary stalk interruption syndrome.
authors.affiliation: Department of Urology, Peking University People's Hospital, Beijing 10044,China; Center of Urology,The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
authors.forename: Wei-min
authors.initials: WM
authors.lastname: Shao
authors.affiliation: Department of Urology, Peking University People's Hospital, Beijing 10044,China.
authors.forename: Wen-jun
authors.initials: WJ
authors.lastname: Bai
authors.affiliation: Department of Urology, Chaozhou People's Hospital, Guangdong Chaozhou 521000,China.
authors.forename: Yi-min
authors.initials: YM
authors.lastname: Chen
authors.affiliation: Department of Urology, The First Hospital of Zhengzhou, Henan, Zhengzhou 450004, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Liu
authors.affiliation: Center of Urology,The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
authors.forename: Yu-jie
authors.initials: YJ
authors.lastname: Wang
mesh_terms: D007987:Gonadotropin-Releasing Hormone / Q000627:therapeutic use*; D006801:Humans; D007006:Hypogonadism / Q000188:drug therapy*; D010902:Pituitary Gland / Q000503:physiopathology*; D011498:Protein Precursors / Q000627:therapeutic use*
chemical_list: D011498:Protein Precursors; C050866:progonadoliberin I; D007987:Gonadotropin-Releasing Hormone