title: MicroRNAs: a new key in lung cancer.
abstract: Lung cancer as a malignance has been killing numerous patients around the world annually, and small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) are the two major types, the later accounting for nearly 80 % of lung cancer. There are multiple causes for lung cancer, and more researches have been carried out to prevent, anticipate, and diagnose the cancer. MicroRNAs (miRNAs) are small non-coding RNA molecules capable of regulating expression of over 50 % of protein-coding genes. The RNA molecules are stable in tissues and blood, so it can tend to be a biomarker in anti-lung cancer. Here, this is a review on the roles of miRNAs for possible ways to prevent lung cancer in clinical trials.
authors.affiliation: Department of Natural Medicine, School of Pharmacy, Fourth Military Medical University, 169 West Changle Road, Xi'an, 710032, People's Republic of China, zhangyunlong8822@sina.com.
authors.forename: Yunlong
authors.initials: Y
authors.lastname: Zhang
authors.forename: Qian
authors.initials: Q
authors.lastname: Yang
authors.forename: Siwang
authors.initials: S
authors.lastname: Wang
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism; D002289:Carcinoma, Non-Small-Cell Lung / Q000235:genetics / Q000473:pathology / Q000517:prevention & control; D002986:Clinical Trials as Topic; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D008175:Lung Neoplasms / Q000235:genetics* / Q000473:pathology / Q000517:prevention & control; D035683:MicroRNAs / Q000235:genetics*; D055752:Small Cell Lung Carcinoma / Q000235:genetics / Q000473:pathology / Q000517:prevention & control
chemical_list: D014408:Biomarkers, Tumor; D035683:MicroRNAs