title: Effect of β-glucan supplementation on acute postprandial changes in fatty acid profile of lymph and serum in pigs.
abstract: Triglycerides are absorbed by the lymphatic system and have various functions in the body. It has been shown that some types of β-glucans have a positive effect on the systemic concentrations of cholesterol and lipid, presumably through interference with the absorption of lipid and/or reabsorption of bile acids. In the current study we investigated the acute effects of ingesting 2 g of β-glucan concentrates derived from barley β-(1→3)(1→4)-D-glucan or yeast β-(1→3)(1→6)-D-glucan on fatty acid content and composition in lymph and serum of 10 female pigs (initial weight 34.7±1.1 kg) fitted with a permanent catheter in the jejunal lymphatic trunk in a cross-over design. Lymph was collected continuously for 8 h followed by a spot sample taken 24 h after. A significant effect of time after feeding was observed for all fatty acids in serum and for 18:0, 18:2ω6 and 18:3ω3 in lymph, but a significant effect of β-glucan was only observed for 14:0 (p=0.049) and 22:6ω3 (p=0.048) in lymph and 18:0 (p=0.019) in serum. While the concentration of dietary fatty acids increased postprandially in lymph, the concentration of arachidonic and docahexanoic acid tended to decrease. Furthermore, there was a drop in concentration of all fatty acid in serum 1 h after the meal.
authors.affiliation: Department of Animal Science, Aarhus University, Blichers Allé 20, 8830 Tjele, Denmark. hellen.laerke@agrsci.dk.
authors.forename: Helle Nygaard
authors.initials: HN
authors.lastname: Lærke
authors.affiliation: Department of Animal Science, Aarhus University, Blichers Allé 20, 8830 Tjele, Denmark. lasse_uha@yahoo.dk.
authors.forename: Lasse Sommer
authors.initials: LS
authors.lastname: Mikkelsen
authors.affiliation: Department of Animal Science, Aarhus University, Blichers Allé 20, 8830 Tjele, Denmark. henry.jorgensen@agrsci.dk.
authors.forename: Henry
authors.initials: H
authors.lastname: Jørgensen
authors.affiliation: Department of Animal Science, Aarhus University, Blichers Allé 20, 8830 Tjele, Denmark. sorenkrogh.jensen@agrsci.dk.
authors.forename: Søren Krogh
authors.initials: SK
authors.lastname: Jensen
mesh_terms: D000818:Animals; D019587:Dietary Supplements; D005227:Fatty Acids / Q000097:blood* / Q000378:metabolism; D005260:Female; D008196:Lymph / Q000378:metabolism*; D013552:Swine; D013997:Time Factors; D047071:beta-Glucans / Q000494:pharmacology*
chemical_list: D005227:Fatty Acids; D047071:beta-Glucans