title: Recent advances of stem cell therapy for retinitis pigmentosa.
abstract: Retinitis pigmentosa (RP) is a group of inherited retinal disorders characterized by progressive loss of photoreceptors and eventually leads to retina degeneration and atrophy. Until now, the exact pathogenesis and etiology of this disease has not been clear, and many approaches for RP therapies have been carried out in animals and in clinical trials. In recent years, stem cell transplantation-based attempts made some progress, especially the transplantation of bone marrow-derived mesenchymal stem cells (BMSCs). This review will provide an overview of stem cell-based treatment of RP and its main problems, to provide evidence for the safety and feasibility for further clinical treatment.
authors.affiliation: Department of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, China. heyuxihot@163.com.
authors.forename: Yuxi
authors.initials: Y
authors.lastname: He
authors.affiliation: Department of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, China. zhangy66@jlu.edu.cn.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, China. emperorsoninlow@163.com.
authors.forename: Xin
authors.initials: X
authors.lastname: Liu
authors.affiliation: Department of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, China. emmaghazaryan@163.com.
authors.forename: Emma
authors.initials: E
authors.lastname: Ghazaryan
authors.affiliation: Department of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, China. lyvoilet@163.com.
authors.forename: Ying
authors.initials: Y
authors.lastname: Li
authors.affiliation: Department of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, China. 13844108986@163.com.
authors.forename: Jianan
authors.initials: J
authors.lastname: Xie
authors.affiliation: Department of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, China. sugf2012@163.com.
authors.forename: Guanfang
authors.initials: G
authors.lastname: Su
mesh_terms: D001854:Bone Marrow Cells / Q000166:cytology* / Q000502:physiology; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000166:cytology* / Q000502:physiology; D012174:Retinitis Pigmentosa / Q000628:therapy*; D033581:Stem Cell Transplantation / Q000379:methods*