title: Cervical cancer biopsy reporting: a review.
abstract: The terminology for reporting human papillomavirus-associated squamous lesions in the cervix, both in tissue samples and cytology specimens, has suffered from many changes throughout the last years creating confusion in interpreting cervical biopsy and cytology reports by clinicians. This review presents a summary and discussion of the current terminology for reporting results of cervical biopsies and cytology with emphasis in the lower anogenital squamous terminology consensus recommendations for tissue specimens and the 2001 Bethesda Workshop for reporting cytology results. Microscopic features of cervical lesions in tissue samples and cytology specimens are presented. Biomarkers, including p16 and Ki-67, are discussed and how they can help the pathologist when dealing with difficult cases.
authors.affiliation: Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: Maria Carolina
authors.initials: MC
authors.lastname: Reyes
authors.forename: Kumarasen
authors.initials: K
authors.lastname: Cooper
mesh_terms: D001706:Biopsy; D003584:Cytological Techniques / Q000379:methods / Q000592:standards*; D005260:Female; D006651:Histocytochemistry / Q000379:methods / Q000592:standards*; D006801:Humans; D008853:Microscopy / Q000379:methods / Q000592:standards*; D012107:Research Design / Q000592:standards*; D009626:Terminology as Topic; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000473:pathology*