title: A new phenyl glycoside from the aerial parts of Equisetum hyemale.
abstract: A new phenyl glycoside, 2-(sophorosyl)-1-(4-hydroxyphenyl)ethanone (9), was isolated from the ethanolic extract of the aerial parts of Equisetum hyemale L., together with eight known compounds (1-8). The structures of these compounds were elucidated using a combination of spectroscopic analyses and chemical method. Of these nine compounds, 4 and 7 showed hepatoprotective effects towards tacrine-induced cytotoxicity in Hep 3B cells with EC50 values of 42.7 ± 1.5 and 132.6 ± 2.8 μM, respectively.
authors.affiliation: a Department of Pharmacy, Yanbian University Hospital , Yanji 133000 , P.R. China.
authors.forename: Mei
authors.initials: M
authors.lastname: Jin
authors.forename: Changhao
authors.initials: C
authors.lastname: Zhang
authors.forename: Tie
authors.initials: T
authors.lastname: Zheng
authors.forename: Dalei
authors.initials: D
authors.lastname: Yao
authors.forename: Le
authors.initials: L
authors.lastname: Shen
authors.forename: Jie
authors.initials: J
authors.lastname: Luo
authors.forename: Zhe
authors.initials: Z
authors.lastname: Jiang
authors.forename: Juan
authors.initials: J
authors.lastname: Ma
authors.forename: Xue-Jun
authors.initials: XJ
authors.lastname: Jin
authors.forename: Jiongmo
authors.initials: J
authors.lastname: Cui
authors.forename: Jung Joon
authors.initials: JJ
authors.lastname: Lee
authors.forename: Gao
authors.initials: G
authors.lastname: Li
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D020829:Equisetum / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D019906:Nuclear Magnetic Resonance, Biomolecular; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D035261:Plant Components, Aerial / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D013619:Tacrine / Q000494:pharmacology
chemical_list: C000594411:2-(sophorosyl)-1-(4-hydroxyphenyl)ethanone; D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D006027:Glycosides; D010636:Phenols; D010936:Plant Extracts; D013619:Tacrine
keywords: 5-hydroymethylfurfural; Equisetum hyemale L; hepatoprotective effect