title: [A case of advanced gastric cancer with multiple liver metastases treated with preoperative TS-1/CDDP chemotherapy and resection, with a complete response and survival for 7 years].
abstract: An 82-year-old man died because of squamous cell carcinoma of the right lung with metastasis to the left femoral bone. At the age of 75 years, he was admitted to our hospital because of hematemesis. Widespread type 3 gastric cancer was detected in the lesser curvature. Computed tomography(CT)showed multiple liver metastases. Preoperative chemotherapy with TS-1/cisplatin(CDDP)was administered. TS-1 was orally administered at 80mg/body/day and CDDP was administered by intravenous infusion at 20mg/body/day every week for 3 weeks and this was followed by a drug-free 2-week period as the first course. After the fourth course, gastrectomy was performed for the primary lesion and radiofrequency ablation(RFA)was performed for the liver metastases. The patient survived for more than 7 years with a complete response (CR)and died thereafter because of squamous cell carcinoma of the lung.
authors.affiliation: Dept. of Surgery, Asada General Hospital.
authors.forename: Maiko
authors.initials: M
authors.lastname: Mitan
authors.forename: Miki
authors.initials: M
authors.lastname: Miyamoto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tsuda
authors.forename: Kouichi
authors.initials: K
authors.lastname: Nishiwaki
authors.forename: Isamu
authors.initials: I
authors.lastname: Kagawa
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Matsumoto
authors.forename: Sosuke
authors.initials: S
authors.lastname: Kishi
authors.forename: Masanao
authors.initials: M
authors.lastname: Yokohira
authors.forename: Katsumi
authors.initials: K
authors.lastname: Imaida
authors.forename: Kousuke
authors.initials: K
authors.lastname: Saoo
mesh_terms: D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001344:Autopsy; D002945:Cisplatin / Q000008:administration & dosage; D004338:Drug Combinations; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008297:Male; D018307:Neoplasms, Squamous Cell / Q000188:drug therapy* / Q000601:surgery; D010094:Oxonic Acid / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000008:administration & dosage; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D002945:Cisplatin