title: Heterologous type of malignant mixed Müllerian tumor of the uterus presenting as a vulvar mass.
abstract: Carcinosarcoma is a rare, extremely aggressive tumor of the uterus with a poor prognosis. The authors describe a case of a 78-year-old woman who presented with a giant mass protruding through the cervix, vagina, and vulva. A total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed. The histopathological examination of the surgical specimen revealed a malignant mixed Müllerian tumor. The clinical and pathological features, molecular data, and prognosis of this aggressive neoplasm are discussed. Although uterine carcinosarcomas are extremely rare, when a postmenopausal woman with a vulvar mass is admitted to the gynecology clinic, the physician should consider that the mass may be a carcinosarcoma.
authors.forename: M
authors.initials: M
authors.lastname: Grigore
authors.forename: C
authors.initials: C
authors.lastname: Ilea
authors.forename: C
authors.initials: C
authors.lastname: Terinte
authors.forename: A
authors.initials: A
authors.lastname: Sava
authors.forename: R
authors.initials: R
authors.lastname: Popovici
mesh_terms: D000368:Aged; D002296:Carcinosarcoma / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D018200:Mixed Tumor, Mullerian / Q000473:pathology* / Q000601:surgery; D010052:Ovariectomy; D058994:Salpingectomy; D014594:Uterine Neoplasms / Q000473:pathology* / Q000601:surgery; D014623:Vaginal Diseases / Q000473:pathology / Q000601:surgery; D014845:Vulvar Diseases / Q000473:pathology / Q000601:surgery