title: Efficacy of insulin lispro in improving glycemic control in gestational diabetes.
abstract: OBJECTIVE
  To assess the safety and efficacy of insulin lispro in improving glycemic control in patients with gestational diabetes.
  
  
  METHODS
  A retrospective observational study was conducted at a single center on 201 gestational women with diabetes. Subjects who received insulin lispro performed blood glucose self-monitoring and recorded the readings in the fasting state and 1 h after each meal. At each contact (in person or telephonic contact), the insulin dose was adjusted based on the readings measured. A total of 53 subjects also recorded glucose levels post-partum. Pregnancy and post-delivery glucose level and insulin requirements of these 53 patients were compared.
  
  
  RESULTS
  Analysis of glucose levels both fasting and post-prandial glucose levels revealed that after using insulin lispro, the number of episodes of post-prandial hyperglycemia (1 h plasma glucose >120 mg/dL) was minimal and so was the incidence of hypoglycemia. Hypoglycemia was defined as a blood sugar value of. There was neither any congenital abnormality except for a poorly formed pinna in the right ear of one baby nor any post-partum complications of note.
  
  
  CONCLUSIONS
  Insulin lispro is an effective and safe treatment option in gestational diabetes.
authors.affiliation: Diabetologist, Madhav Diabetes Centre, Anna Nagar, Chennai, India.
authors.forename: M C
authors.initials: MC
authors.lastname: Deepaklal
authors.affiliation: Cons. Obstetrician and Gynaecology, Joseph Nursing Home, Chennai, India.
authors.forename: Kurian
authors.initials: K
authors.lastname: Joseph
authors.affiliation: Cons. Obstetrician and Gynaecology, Joseph Nursing Home, Chennai, India.
authors.forename: Rekha
authors.initials: R
authors.lastname: Kurian
authors.affiliation: Dr. Nandita's Fertility Centre, Chetput, Chennai, India.
authors.forename: Nandita A
authors.initials: NA
authors.lastname: Thakkar
keywords: Efficacy; gestational diabetes; hyperglycemia; hypoglycemia; insulin iispro; macrosomia