title: De Quervain thyroiditis in the course of H1N1 influenza infection.
abstract: OBJECTIVE
  Viral infections have been frequently associated with subacute (De Quervain) thyroiditis and autoimmune thyroid diseases. In the present case report we document a rare case of De Quervain thyroiditis in the course of H1N1 influenza infection.
  
  
  METHODS
  A 17-year-old previously healthy female that was treated in the General Hospital of Kalamata developed an influenza-like syndrome that was accompanied by palpitations, thyroid enlargement, and increased C-reactive protein. Polymerase chain reaction assay confirmed the diagnosis of H1N1 virus infection. Serum thyroid-stimulating hormone was suppressed to zero while the levels of free thyroxine and triiodothyronine were increased. The patient was treated with non-steroidal anti-inflammatory drugs and thyroid function was gradually restored without evolving to a hypothyroid phase.
  
  
  CONCLUSIONS
  To our knowledge this is the second case described in the literature of De Quervain thyroiditis associated with H1N1 influenza infection.
authors.affiliation: Department of Internal Medicine, General Hospital of Kalamata, Kalamata, Greece.
authors.forename: G
authors.initials: G
authors.lastname: Michas
authors.affiliation: Department of Internal Medicine, General Hospital of Kalamata, Kalamata, Greece.
authors.forename: G
authors.initials: G
authors.lastname: Alevetsovitis
authors.affiliation: Department of Internal Medicine, General Hospital of Kalamata, Kalamata, Greece.
authors.forename: I
authors.initials: I
authors.lastname: Andrikou
authors.affiliation: Department of Internal Medicine, General Hospital of Kalamata, Kalamata, Greece.
authors.forename: S
authors.initials: S
authors.lastname: Tsimiklis
authors.affiliation: Department of Internal Medicine, General Hospital of Kalamata, Kalamata, Greece ; North Middlesex University Hospital NHS Trust, London, UK.
authors.forename: E
authors.initials: E
authors.lastname: Vryonis
keywords: De Quervain thyroiditis; H1N1 virus