title: Oncologic validity of recipient vessel preservation in microvascular free-flap reconstruction.
abstract: OBJECTIVE
  The use of free-flap reconstruction requires a more limited neck dissection to allow for microvascular anastomosis. This study seeks to determine the oncologic validity of cervical vessel preservation.
  
  
  METHODS
  The current study is a prospective review of cervical vessel biopsies from patients undergoing resection of squamous cell carcinoma (SCCA) tumors of the head and neck with free tissue reconstruction.
  
  
  RESULTS
  From June 2010 to March 2012, 227 recipient vessel biopsies were performed on 100 patients. Three of these patients had grossly abnormal vessels, with malignancy confirmed by frozen section analysis. One patient had a vessel positive for malignancy that was grossly normal but found to have SCCA on the final pathology.
  
  
  CONCLUSIONS
  When the recipient vessel appears grossly suspicious, a frozen section biopsy and re-resection should be considered. Recipient vessel trimmings should routinely be sent for permanent pathology since in rare cases, they can be involved by tumor, affecting the margin status, prognosis, and indications for adjuvant therapy.
authors.affiliation: Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, Calif., USA.
authors.forename: Adam S
authors.initials: AS
authors.lastname: DeConde
authors.forename: Christopher F
authors.initials: CF
authors.lastname: Thompson
authors.forename: Soroush
authors.initials: S
authors.lastname: Zaghi
authors.forename: Darshni
authors.initials: D
authors.lastname: Vira
authors.forename: Keith E
authors.initials: KE
authors.lastname: Blackwell
authors.forename: Vishad
authors.initials: V
authors.lastname: Nabili
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D005260:Female; D006258:Head and Neck Neoplasms / Q000601:surgery*; D006801:Humans; D008297:Male; D008866:Microsurgery / Q000379:methods*; D008875:Middle Aged; D009333:Neck / Q000098:blood supply*; D037981:Neck Dissection; D011446:Prospective Studies; D019651:Plastic Surgery Procedures / Q000379:methods*; D015203:Reproducibility of Results; D000077195:Squamous Cell Carcinoma of Head and Neck; D013524:Surgical Flaps / Q000098:blood supply*