title: [Spondylosclerosis hemispherica: a rare radiological syndrome of the spine].
abstract: BACKGROUND
  Spondylosclerosis hemispherica is a rare syndrome of the spine and was described first by Dihlmann. The typical radiographic appearance is a hemispherical sclerosis of the vertebral body, which is accompanied by pain in the affected region. Usually it appears at the lower lumbar spine. The etiology varies and includes degenerative disk diseases, scoliosis, bacterial infections, ankylosing spondylitis, osteoid osteoma, and malignant diseases.The radiological findings of 2 patients with spondylosclerosis hemispherica are presented and the current literature discussed.
  
  
  METHODS
  Two women (33 and 60 years old) with spondylosclerosis hemispherica of the lower spine suffered from low back pain and fulfilled all criteria of Dihlmann's description. Malignant disease was excluded in both cases with a broad diagnostic workup (lab values, x-ray, CT scan, MRI) and in one case a biopsy from the affected vertebra was taken.
  
  
  RESULTS
  In both cases all radiological findings demonstrated the typical changes of spondylosclerosis hemispherica with sclerosis of the vertebra body and erosions at the upper and inferior end plates. Malignant disease was excluded in one case with a biopsy and in the other case with noninvasive diagnostic procedures. Both patients were treated nonsurgically. During clinical follow-up, the patients were in a good condition with decreasing regional low back pain and no ongoing radiological changes in the affected vertebral bodies.
  
  
  CONCLUSIONS
  Spondylosclerosis hemispherica is a syndrome with a typical radiographic appearance. The etiology of spondylosclerosis hemispherica is manifold; however, malignancy must be excluded. In most cases, noninvasive diagnostics are sufficient to rule out malignant growth even in cases with concomitant degenerative changes of the affected segment. Thus, there is no need for a biopsy except in cases with ambiguous results. Subsequently, close clinical and radiological follow-up of the patients with spondylosclerosis hemispherica is necessary.
authors.affiliation: Klinik und Poliklinik für Orthopädie, Universität Leipzig, Liebigstraße 20, 04103, Leipzig, Deutschland, heyde@uniklinik-leipzig.de.
authors.forename: C E
authors.initials: CE
authors.lastname: Heyde
authors.forename: T
authors.initials: T
authors.lastname: Kahn
authors.forename: N H
authors.initials: NH
authors.lastname: von der Höh
authors.forename: A
authors.initials: A
authors.lastname: Völker
authors.forename: J
authors.initials: J
authors.lastname: Gulow
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D035583:Rare Diseases / Q000175:diagnosis / Q000628:therapy; D012598:Sclerosis; D012600:Scoliosis / Q000175:diagnosis* / Q000628:therapy*; D013131:Spine / Q000000981:diagnostic imaging* / Q000473:pathology*; D055009:Spondylosis / Q000175:diagnosis* / Q000628:therapy*; D013577:Syndrome; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome