title: Effects of Acute Active Video Games on Endothelial Function Following a High-Fat Meal in Overweight Adolescents.
abstract: BACKGROUND
  We tested the hypothesis that an active video game following a high-fat meal would partially prevent the unfavorable effect of a high-fat meal on vascular function in overweight adolescents.
  
  
  METHODS
  Twenty-four overweight adolescents were randomized to either a 60-minute active video game (AVG) group (n = 12) or seated rest (SR) as a control group (n = 12) after a high-fat meal. Blood parameters were measured, and vascular function was measured using brachial artery flow-mediated dilation (FMD) at baseline and 3 hours after a high-fat meal.
  
  
  RESULTS
  No significant interaction was found in any blood parameter. A high-fat meal significantly increased blood triglyceride and glucose concentrations in both groups in a similar manner. Brachial artery FMD significantly decreased in the SR group (13.8 ± 3.2% to 11.8 ± 2.5), but increased in the AVG group (11.4 ± 4.0% to 13.3 ± 3.5), with a significant interaction (P = .034).
  
  
  CONCLUSIONS
  These findings show that an active video game attenuated high-fat meal-induced endothelial dysfunction. This suggests that an active video game may have a cardioprotective effect on endothelial function in overweight adolescents when exposed to a high-fat meal.
authors.affiliation: Dept of Sport Science, University of Seoul, Seoul, South Korea.
authors.forename: Soo Hyun
authors.initials: SH
authors.lastname: Park
authors.forename: Eun Sun
authors.initials: ES
authors.lastname: Yoon
authors.forename: Yong Hee
authors.initials: YH
authors.lastname: Lee
authors.forename: Chul-Ho
authors.initials: CH
authors.lastname: Kim
authors.forename: Kanokwan
authors.initials: K
authors.lastname: Bunsawat
authors.forename: Kevin S
authors.initials: KS
authors.lastname: Heffernan
authors.forename: Bo
authors.initials: B
authors.lastname: Fernall
authors.forename: Sae Young
authors.initials: SY
authors.lastname: Jae
mesh_terms: D000293:Adolescent; D004041:Dietary Fats; D004730:Endothelium, Vascular / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D050177:Overweight / Q000503:physiopathology*; D018910:Video Games / Q000009:adverse effects*
chemical_list: D004041:Dietary Fats