title: Comparison of the effects of low volume prilocaine and alkalinized prilocaine for the regional intravenous anesthesia technique in hand and wrist surgery.
abstract: OBJECTIVE
  Comparing the effectivity of prilocaine and prilocaine alkalinized with 8.4% NaHCO3 in terms of sensory and motor block onset and termination durations in RIVA technique considering patients' satisfaction and tolerance with application of tourniquet undergoing hand-wrist surgery.
  
  
  METHODS
  64 patients were randomised into two groups. First group (Group P) was administered prilocaine and second group (Group PN) was administered prilocaine + %8.4 NaHCO3. Sensory and motor block onset and termination times and onset of tourniquet pain were recorded.
  
  
  RESULTS
  No significant difference was found between the two groups in terms of onset and termination of sensory block and the onset of motor block. The duration of the motor block was longer in Group PN than in Group P (P < 0.05). Tourniquet pain was more intense in Group P (P = 0.036). In Group PN, the use of additional drugs was recorded at a lower rate and patients' satisfaction was higher than Group P.
  
  
  CONCLUSIONS
  In the present study, it was established that alkalinization of prilocaine had no effect on the duration of sensory block and it prolonged the duration of motor block, increased patients' satisfaction, and decreased tourniquet pain. It is our suggestion that future studies should be carried out on the issue by using different volumes.
authors.affiliation: Department of Anesthesiology and Reanimation, Training and Research Hospital, Vatan Caddesi No. 33, Demetevler, 06200 Ankara, Turkey.
authors.forename: Ozlem
authors.initials: O
authors.lastname: Kapusuz
authors.affiliation: Department of Anesthesiology and Reanimation, Training and Research Hospital, Vatan Caddesi No. 33, Demetevler, 06200 Ankara, Turkey.
authors.forename: Guldeniz
authors.initials: G
authors.lastname: Argun
authors.affiliation: Department of Orthopedics and Traumatology, Oncology Training and Research Hospital, Vatan Caddesi No. 33, Demetevler, 06200 Ankara, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Arikan
authors.affiliation: Department of Orthopedics and Traumatology, Oncology Training and Research Hospital, Vatan Caddesi No. 33, Demetevler, 06200 Ankara, Turkey.
authors.forename: Guray
authors.initials: G
authors.lastname: Toğral
authors.affiliation: Department of Anesthesiology and Reanimation, Training and Research Hospital, Vatan Caddesi No. 33, Demetevler, 06200 Ankara, Turkey.
authors.forename: Aysun
authors.initials: A
authors.lastname: Basarir
authors.affiliation: Department of Anesthesiology and Reanimation, Training and Research Hospital, Vatan Caddesi No. 33, Demetevler, 06200 Ankara, Turkey.
authors.forename: Nihal
authors.initials: N
authors.lastname: Kadiogullari
mesh_terms: D000468:Alkalies / Q000737:chemistry*; D000765:Anesthesia, Conduction; D000771:Anesthesia, Intravenous; D005260:Female; D006225:Hand / Q000601:surgery*; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D009407:Nerve Block; D010147:Pain Measurement; D017060:Patient Satisfaction; D011318:Prilocaine / Q000494:pharmacology*; D012677:Sensation; D013997:Time Factors; D014111:Tourniquets; D014953:Wrist / Q000601:surgery*
chemical_list: D000468:Alkalies; D011318:Prilocaine