title: Medical management in type B aortic dissection.
abstract: Medical management is generally the preferred treatment for uncomplicated type B acute aortic dissection cases. It is often centered on the use of antihypertensive agents, which alleviates hemodynamic stress on the damaged aortic wall. Methods of medical management and drug selection are still based mainly on personal experience, expert opinion and historical observational studies as randomized controlled studies are lacking. Guidelines from European (ESC), American (ACC/AHA) and Asian (Japan) societies in the last decade have made recommendations on use of medications, but also reaffirmed the lack of evidence for therapeutic approaches and targeted medical management. More recent evidence suggests that there may be type-selective benefits for antihypertensive medications. Here, we will discuss the present understanding of medical management of acute aortic dissection.
authors.affiliation: 1 The University of Tokyo, Tokyo, Japan ; 2 University of Michigan, Ann Arbor, MI, USA ; 3 Cardiology Division, "Cava de' Tirreni and Amalfi Coast" Hospital, Heart Department, University of Salerno, Italy ; 4 IRCCS Policlinico San Donato, San Donato Milanese, Italy ; 5 Massachusetts General Hospital, Boston, MA, USA.
authors.forename: Toru
authors.initials: T
authors.lastname: Suzuki
authors.affiliation: 1 The University of Tokyo, Tokyo, Japan ; 2 University of Michigan, Ann Arbor, MI, USA ; 3 Cardiology Division, "Cava de' Tirreni and Amalfi Coast" Hospital, Heart Department, University of Salerno, Italy ; 4 IRCCS Policlinico San Donato, San Donato Milanese, Italy ; 5 Massachusetts General Hospital, Boston, MA, USA.
authors.forename: Kim A
authors.initials: KA
authors.lastname: Eagle
authors.affiliation: 1 The University of Tokyo, Tokyo, Japan ; 2 University of Michigan, Ann Arbor, MI, USA ; 3 Cardiology Division, "Cava de' Tirreni and Amalfi Coast" Hospital, Heart Department, University of Salerno, Italy ; 4 IRCCS Policlinico San Donato, San Donato Milanese, Italy ; 5 Massachusetts General Hospital, Boston, MA, USA.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Bossone
authors.affiliation: 1 The University of Tokyo, Tokyo, Japan ; 2 University of Michigan, Ann Arbor, MI, USA ; 3 Cardiology Division, "Cava de' Tirreni and Amalfi Coast" Hospital, Heart Department, University of Salerno, Italy ; 4 IRCCS Policlinico San Donato, San Donato Milanese, Italy ; 5 Massachusetts General Hospital, Boston, MA, USA.
authors.forename: Andrea
authors.initials: A
authors.lastname: Ballotta
authors.affiliation: 1 The University of Tokyo, Tokyo, Japan ; 2 University of Michigan, Ann Arbor, MI, USA ; 3 Cardiology Division, "Cava de' Tirreni and Amalfi Coast" Hospital, Heart Department, University of Salerno, Italy ; 4 IRCCS Policlinico San Donato, San Donato Milanese, Italy ; 5 Massachusetts General Hospital, Boston, MA, USA.
authors.forename: James B
authors.initials: JB
authors.lastname: Froehlich
authors.affiliation: 1 The University of Tokyo, Tokyo, Japan ; 2 University of Michigan, Ann Arbor, MI, USA ; 3 Cardiology Division, "Cava de' Tirreni and Amalfi Coast" Hospital, Heart Department, University of Salerno, Italy ; 4 IRCCS Policlinico San Donato, San Donato Milanese, Italy ; 5 Massachusetts General Hospital, Boston, MA, USA.
authors.forename: Eric M
authors.initials: EM
authors.lastname: Isselbacher
keywords: Aortic dissection; medication