title: Natural products; pharmacological importance of family Cucurbitaceae: a brief review.
abstract: Compounds derived from nature have played a major role in drug discovery. They became the basis for the development of new pharmaceuticals. In this scope, family Cucurbitaceae is a prominent source of secondary metabolites, mainly triterpenoids. In this paper, we provide a brief review of cucurbitane metabolites that exhibit an extensive range of biological actions specifically antidiabetic, anti-inflammatory, cytotoxic, hepatoprotective, and antiparasitic effects.
authors.forename: Syed Shoaib Ahmad
authors.initials: SS
authors.lastname: Shah
authors.forename: M Ijaz
authors.initials: MI
authors.lastname: Hussain
authors.forename: M Kashif
authors.initials: MK
authors.lastname: Aslam
authors.affiliation: Centro de Biotecnologia Genomica, Instituto Politecnico Nacional, Boulevard del Maestro, s/n, Esq. Elías Piña, 88710, Reynosa, Mexico. gildardors@hotmail.com.
authors.forename: Gildardo
authors.initials: G
authors.lastname: Rivera
mesh_terms: D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000592:standards; D000970:Antineoplastic Agents / Q000737:chemistry / Q000592:standards; D000977:Antiparasitic Agents / Q000737:chemistry / Q000592:standards; D001688:Biological Products / Q000737:chemistry* / Q000592:standards; D019662:Cucurbitaceae / Q000737:chemistry*; D055808:Drug Discovery / Q000639:trends*; D006801:Humans; D007004:Hypoglycemic Agents / Q000737:chemistry / Q000592:standards
chemical_list: D000893:Anti-Inflammatory Agents; D000970:Antineoplastic Agents; D000977:Antiparasitic Agents; D001688:Biological Products; D007004:Hypoglycemic Agents