title: Having a promising efficacy on type II diabetes, it's definitely a green tea time.
abstract: The beneficial effects of green tea have been confirmed in various diseases, such as different types of cancer, heart disease, and liver disease. The effective components of green tea mainly include tea polysaccharides and tea polyphenols, such as catechin, particularly (-)-epigallocatechin-3-gallate. Increasing in vivo and in vitro evidences have explored the potential molecular mechanisms of green tea as well as the specific biological actions. Moreover, clinical trials have also explored the potential value of green tea components in treating metabolic syndromes, such as obesity, type II diabetes, and cardiovascular disease. This study explores the effects of the two major green tea components on the improvement of type II diabetes. It is concluded that regular consumption of green tea is beneficial for the improvement of high-fat dietary-induced obesity and type II diabetes.
authors.forename: Hen
authors.initials: H
authors.lastname: Jiao
authors.forename: Guohua
authors.initials: G
authors.lastname: Hu
authors.forename: Dayong
authors.initials: D
authors.lastname: Gu
authors.affiliation: Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. ni.xiaoling@zs-hospital.sh.cn.
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Ni
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification / Q000627:therapeutic use; D002392:Catechin / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003924:Diabetes Mellitus, Type 2 / Q000517:prevention & control*; D006801:Humans; D007004:Hypoglycemic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000627:therapeutic use; D007328:Insulin / Q000378:metabolism; D059808:Polyphenols / Q000737:chemistry / Q000302:isolation & purification / Q000627:therapeutic use; D011134:Polysaccharides / Q000737:chemistry / Q000302:isolation & purification / Q000627:therapeutic use; D015398:Signal Transduction; D013662:Tea / Q000737:chemistry* / Q000378:metabolism
chemical_list: D000975:Antioxidants; D007004:Hypoglycemic Agents; D007328:Insulin; D059808:Polyphenols; D011134:Polysaccharides; D013662:Tea; D002392:Catechin; C045651:epigallocatechin gallate