title: Effect of calcium-ozone treatment on chemical and biological properties of polyethylene terephthalate.
abstract: Ozone (O3 ) treatment of polyethylene terephthalate (PET) in distilled water was performed in the presence and absence of calcium (Ca(2+) ). PET was oxidized and thus carboxylic and hydroxyl functional groups were introduced on its surface after O3 treatment, regardless of the presence or absence of Ca(2+) . In the case of O3 treatment with Ca(2+) , PET surface was modified with Ca(2+) . Ca(2+) immobilization was confirmed by X-ray photoelectron spectrometric analysis. Hydrophilicity was investigated by measuring contact angles (CA). CA of PET decreased significantly after ozonation. Surface topography of PET before and after ozone treatment was observed by scanning electron microscopy, and showed no morphological changes. In vitro studies showed enhanced rat bone marrow cell responses on the O3 -treated PET surface. Ca(2+) -O3 oxidation at 37°C for 6 h is expected to be an effective method to fabricate PET with good biocompatibility.
authors.affiliation: Department of Biomaterials, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
authors.forename: Ahmed Nafis
authors.initials: AN
authors.lastname: Rashid
authors.forename: Kanji
authors.initials: K
authors.lastname: Tsuru
authors.forename: Kunio
authors.initials: K
authors.lastname: Ishikawa
mesh_terms: D000818:Animals; D001854:Bone Marrow Cells / Q000166:cytology / Q000378:metabolism*; D002118:Calcium / Q000737:chemistry*; D002478:Cells, Cultured; D057927:Hydrophobic and Hydrophilic Interactions; D008422:Materials Testing; D010126:Ozone / Q000737:chemistry*; D011093:Polyethylene Terephthalates / Q000737:chemistry*; D051381:Rats
chemical_list: D011093:Polyethylene Terephthalates; D010126:Ozone; D002118:Calcium
keywords: biocompatibility; calcium modification; ozone treatment; poly(ethylene terephthalate)