title: Short and long-term outcomes of systemic drainage to IVC: a new technique for pancreas transplantation.
abstract: Ninety-eight percent of the whole pancreas does not serve the purpose of pancreatic transplantation and it is a major cause of surgical complications. Up to 30% of pancreas transplant recipients experience surgical complications and require reoperation. Graft thrombosis and pancreatitis are the most common complications of pancreas transplantation (PT). Thus, different surgical techniques have been described to overcome the surgical hurdles and reduce surgical complications. In this study, for the first time, we report short- and long-term outcomes of PT with inferior vena cava (IVC) venous drainage. Forty-five PTs (22 simultaneous pancreas and kidney [SPK] transplantations and 23 pancreas after kidney [PAK] transplantations) were performed with this technique in our center. Sixty-eight percent of the donors were imported from outside of our area after they were declined by their local transplantation center. Patient and graft survival rates were 100% at 1 year. No graft thrombosis or pancreatitis occurred with this technique. Six patients (13.3%) required reoperation (3 bleeding, 2 anastomotic leak, and 1 small bowel perforation). No patient or graft loss occurred due to surgical complications. We conclude that this technique provides fast and easy dissection of the venous drainage of the PT without the need of complete occlusion of venous outflow. Surgical complication rates were lower with this technique compared with other reported techniques.
authors.affiliation: Surgery, SUNY at Buffalo, Buffalo, New York, United States. Electronic address: mlaftavi@buffalo.edu.
authors.forename: M R
authors.initials: MR
authors.lastname: Laftavi
authors.affiliation: Medicine, SUNY at Buffalo, Buffalo, New York, United States.
authors.forename: O
authors.initials: O
authors.lastname: Pankewycz
authors.affiliation: Medicine, SUNY at Buffalo, Buffalo, New York, United States.
authors.forename: R
authors.initials: R
authors.lastname: Kohli
authors.affiliation: Surgery, SUNY at Buffalo, Buffalo, New York, United States.
authors.forename: L
authors.initials: L
authors.lastname: Feng
authors.affiliation: Surgery, SUNY at Buffalo, Buffalo, New York, United States.
authors.forename: M
authors.initials: M
authors.lastname: Said
authors.affiliation: Surgery, SUNY at Buffalo, Buffalo, New York, United States.
authors.forename: R
authors.initials: R
authors.lastname: Sharma
authors.affiliation: Surgery, SUNY at Buffalo, Buffalo, New York, United States.
authors.forename: S
authors.initials: S
authors.lastname: Patel
mesh_terms: D000328:Adult; D004322:Drainage / Q000379:methods; D005260:Female; D006085:Graft Survival; D006801:Humans; D008297:Male; D008875:Middle Aged; D016035:Pancreas Transplantation / Q000009:adverse effects / Q000379:methods*; D011183:Postoperative Complications / Q000517:prevention & control; D012086:Reoperation; D014019:Tissue Donors; D016896:Treatment Outcome; D014682:Vena Cava, Inferior / Q000601:surgery