title: Thiol-activated gem-dithiols: a new class of controllable hydrogen sulfide donors.
abstract: A class of novel thiol-activated H2S donors has been developed on the basis of the gem-dithiol template. These donors release H2S in the presence of cysteine or GSH in aqueous solutions as well as in cellular environments.
authors.affiliation: Department of Chemistry, Washington State University , Pullman, Washington 99164, United States.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhao
authors.forename: Jianming
authors.initials: J
authors.lastname: Kang
authors.forename: Chung-Min
authors.initials: CM
authors.lastname: Park
authors.forename: Powell E
authors.initials: PE
authors.lastname: Bagdon
authors.forename: Bo
authors.initials: B
authors.lastname: Peng
authors.forename: Ming
authors.initials: M
authors.lastname: Xian
mesh_terms: D003545:Cysteine / Q000737:chemistry; D005978:Glutathione / Q000737:chemistry; D006862:Hydrogen Sulfide / Q000737:chemistry*; D015394:Molecular Structure; D013438:Sulfhydryl Compounds / Q000737:chemistry*; D014050:Toluene / Q000031:analogs & derivatives* / Q000737:chemistry
chemical_list: D013438:Sulfhydryl Compounds; D014050:Toluene; D005978:Glutathione; D003545:Cysteine; C004848:dithiol; D006862:Hydrogen Sulfide