title: Non-occupational post-exposure prophylaxis for HIV: 10-year retrospective analysis in Seattle, Washington.
abstract: Despite treatment guidelines in place since 2005, non-occupational post-exposure HIV prophylaxis (nPEP) remains an underutilized prevention strategy. We conducted a retrospective chart review of patients presenting to a publicly-funded HIV clinic in Seattle, Washington for nPEP between 2000 and 2010 (N = 360). nPEP prescriptions were provided for 324 (90%) patients; 83% of prescription decisions were appropriate according to Centers for Disease Control and Prevention guidelines, but only 31% (N = 111/360) of patients were considered "high risk." In order to use limited resources most efficiently, public health agencies should target messaging for this high-cost intervention to individuals with high-risk HIV exposures.
authors.affiliation: Department of Medicine, University of Washington, Seattle, Washington, United States of America.
authors.forename: Sarah J
authors.initials: SJ
authors.lastname: McDougal
authors.affiliation: Department of Medicine, University of Washington, Seattle, Washington, United States of America; Veterans Affairs Puget Sound, General Medicine Service, Seattle, Washington, United States of America.
authors.forename: Jeremiah
authors.initials: J
authors.lastname: Alexander
authors.affiliation: Department of Medicine, University of Washington, Seattle, Washington, United States of America.
authors.forename: Shireesha
authors.initials: S
authors.lastname: Dhanireddy
authors.affiliation: Department of Medicine, University of Washington, Seattle, Washington, United States of America.
authors.forename: Robert D
authors.initials: RD
authors.lastname: Harrington
authors.affiliation: Department of Medicine, University of Washington, Seattle, Washington, United States of America; Department of Epidemiology, University of Washington, Seattle, Washington, United States of America.
authors.forename: Joanne D
authors.initials: JD
authors.lastname: Stekler
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008875:Middle Aged; D056990:Post-Exposure Prophylaxis; D012189:Retrospective Studies; D012307:Risk Factors; D014861:Washington; D055815:Young Adult
chemical_list: D019380:Anti-HIV Agents