title: [Experience in kidney transplantation without blood transfusion: kidney transplantation transfusion-free in Jehovah's Witnesses. First communication in Mexico].
abstract: BACKGROUND
  Jehovah's Witness refuse blood transfusion, but they accept organ transplantation, albumin, immunoglobulin, vaccines and clotting factors.
  
  
  METHODS
  We present 3 kidney transplants in Jehovah's Witness patients (two male and one female) without blood transfusion, with a mean age of 31.33 years and a mean body mass index of 20.99 kg/m(2). All patients underwent pretransplant peritoneal dialysis for an average of 52.3 months. Two transplants came from living donors and one from a deceased donor with a cold ischemia of 23 hours. The donors were two females and one male, with a mean age of 34.33 years. All patients received pretransplant erythropoietin and iron dextran and an intraoperative cell saver was used. Hemoglobin, hematocrit, red blood cells and serum creatinine levels, as well as the glomerular filtration at 24 months postransplant were stable. All patients received induction with basiliximab and initial immunosuppression with calcineurin inhibitors. One of the patients had a perirenal hematoma as a complication, which required a surgery 20 days post-transplant. At 5, 26 and 36 months postransplant the three patients are alive and with functional grafts.
  
  
  CONCLUSIONS
  It is possible to perform kidney transplantation without transfusion in Jehovah's Witness, obtaining an acceptable global survival without acute rejection.
authors.affiliation: Universidad Anáhuac México Norte, Veracruz, Veracruz, Mexico.
authors.forename: Liliana Stefany
authors.initials: LS
authors.lastname: Hernández-Navarrete
authors.affiliation: Universidad Juárez Autónoma de Tabasco, Mexico.
authors.forename: Jesús Diego
authors.initials: JD
authors.lastname: Hernández-Jiménez
authors.affiliation: Departamento de Trasplantes, IMSS UMAE 189 Adolfo Ruiz Cortines. Veracruz, México.
authors.forename: Luis Alfredo
authors.initials: LA
authors.lastname: Jiménez-López
authors.affiliation: Departamento de Trasplantes, IMSS UMAE 189 Adolfo Ruiz Cortines. Veracruz, México.
authors.forename: Luis Filadelfo
authors.initials: LF
authors.lastname: Budar-Fernández
authors.affiliation: Departamento de Trasplantes, IMSS UMAE 189 Adolfo Ruiz Cortines. Veracruz, México.
authors.forename: Marco Tulio
authors.initials: MT
authors.lastname: Méndez-López
authors.affiliation: Departamento de Trasplantes, IMSS UMAE 189 Adolfo Ruiz Cortines. Veracruz, México. gmtzmier@hotmail.com.
authors.forename: Gustavo
authors.initials: G
authors.lastname: Martínez-Mier
mesh_terms: D000328:Adult; D000740:Anemia / Q000517:prevention & control; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D000077552:Basiliximab; D001803:Blood Transfusion / Q000941:ethics / Q000523:psychology; D004921:Erythropoietin / Q000627:therapeutic use; D005260:Female; D005921:Glomerulonephritis / Q000601:surgery; D006397:Hematinics / Q000627:therapeutic use; D006403:Hematologic Tests; D006406:Hematoma / Q000209:etiology / Q000601:surgery; D006801:Humans; D007505:Iron-Dextran Complex / Q000627:therapeutic use; D033221:Jehovah's Witnesses / Q000523:psychology; D007668:Kidney / Q000098:blood supply; D007677:Kidney Function Tests; D016030:Kidney Transplantation / Q000379:methods*; D008297:Male; D008800:Mexico; D057725:Operative Blood Salvage / Q000295:instrumentation / Q000379:methods*; D010342:Patient Acceptance of Health Care; D011183:Postoperative Complications / Q000517:prevention & control; D019106:Postoperative Hemorrhage / Q000209:etiology / Q000601:surgery; D011993:Recombinant Fusion Proteins / Q000627:therapeutic use; D016896:Treatment Outcome; D016312:Treatment Refusal; D055815:Young Adult
chemical_list: D000911:Antibodies, Monoclonal; D006397:Hematinics; D011993:Recombinant Fusion Proteins; D004921:Erythropoietin; D007505:Iron-Dextran Complex; D000077552:Basiliximab
keywords: Jehovah's Witness; Kidney transplantation; Testigos de Jehová; blood transfusion; transfusión sanguínea; trasplante renal