title: PAIN OUT: the making of an international acute pain registry.
abstract: BACKGROUND
  About 240 million patients undergo surgery every year, worldwide. Roughly 50% of these patients report clinically significant pain. Numerous barriers impede provision of adequate management. Lack of evidence about appropriateness and effectiveness of interventions is one. A registry can provide such information, eventually facilitating better management. This paper reports the development and feasibility of PAIN OUT, the first international acute pain registry, established with funds from the European Commission, and presents preliminary analysis to illustrate the nature of investigations that registry data make possible.
  
  
  METHODS
  On the first postoperative day, 6347 adult patients undergoing orthopaedic or general surgery, in 11 medical centres in Europe and Israel, provided Patient Reported Outcomes (PROs) using a validated questionnaire. Clinical data were abstracted from the patient's chart.
  
  
  RESULTS
  Feasibility worked well. Over a period of 1 year, surveyors accrued targeted data sets and entered them into an online browser. Collaborators could receive online feedback comparing their findings about PROs against anonymized findings from other centres. Missing data for the majority of variables were low. Despite considerable variability between institutions, a large number of patients were treated according to the generic, evidence-based recommendations we assessed. However, this was not sufficient to result in acceptable outcomes for the majority of patients.
  
  
  CONCLUSIONS
  The initial development of PAIN OUT has been achieved. From 2013, it continues as a not-for-profit academic project, open to clinicians and researchers worldwide. The International Association for Study of Pain and PAIN OUT will work together to maintain, disseminate and develop the registry.
authors.affiliation: Department of Anesthesiology & Intensive Care, Friedrich-Schiller University Hospital, Jena, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Zaslansky
authors.forename: J
authors.initials: J
authors.lastname: Rothaug
authors.forename: C R
authors.initials: CR
authors.lastname: Chapman
authors.forename: R
authors.initials: R
authors.lastname: Bäckström
authors.forename: S
authors.initials: S
authors.lastname: Brill
authors.forename: D
authors.initials: D
authors.lastname: Fletcher
authors.forename: L
authors.initials: L
authors.lastname: Fodor
authors.forename: D B
authors.initials: DB
authors.lastname: Gordon
authors.forename: M
authors.initials: M
authors.lastname: Komann
authors.forename: C
authors.initials: C
authors.lastname: Konrad
authors.forename: Y
authors.initials: Y
authors.lastname: Leykin
authors.forename: E
authors.initials: E
authors.lastname: Pogatski-Zahn
authors.forename: M M
authors.initials: MM
authors.lastname: Puig
authors.forename: N
authors.initials: N
authors.lastname: Rawal
authors.forename: K
authors.initials: K
authors.lastname: Ullrich
authors.forename: T
authors.initials: T
authors.lastname: Volk
authors.forename: W
authors.initials: W
authors.lastname: Meissner
mesh_terms: D059787:Acute Pain / Q000175:diagnosis / Q000628:therapy*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005060:Europe; D005240:Feasibility Studies; D005260:Female; D006761:Hospitals; D006801:Humans; D008297:Male; D008875:Middle Aged; D059408:Pain Management; D010149:Postoperative Pain / Q000175:diagnosis / Q000628:therapy*; D012042:Registries; D011795:Surveys and Questionnaires