title: Plant secondary metabolites- potent inhibitors of monoamine oxidase isoforms.
abstract: Target of monoamine oxidase inhibitions are considered as the treatment of depressive states and neurodegenerative disorders, including Parkinson’s and Alzheimer’s diseases. Many medicinal chemistry research groups are actively working in this area for the development of most promising selective MAO inhibitors. Many plant isolates also showed remarkable MAO inhibition in recent years. The objective of this review is to identify the major MAO inhibitors secondary metabolites from plants like flavonoids, alkaloids and xanthones class of compounds.
authors.forename: Bijo
authors.initials: B
authors.lastname: Mathew
authors.forename: Jerad
authors.initials: J
authors.lastname: Suresh
authors.forename: Githa E
authors.initials: GE
authors.lastname: Mathew
authors.forename: Ramamoorthy
authors.initials: R
authors.lastname: Parasuraman
authors.forename: Nalakathu
authors.initials: N
authors.lastname: Abdulla
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000378:metabolism / Q000627:therapeutic use; D000818:Animals; D047309:Flavones / Q000737:chemistry / Q000378:metabolism / Q000627:therapeutic use; D006801:Humans; D008995:Monoamine Oxidase / Q000737:chemistry / Q000378:metabolism*; D008996:Monoamine Oxidase Inhibitors / Q000737:chemistry / Q000378:metabolism* / Q000627:therapeutic use; D019636:Neurodegenerative Diseases / Q000188:drug therapy / Q000378:metabolism; D010936:Plant Extracts / Q000737:chemistry / Q000378:metabolism* / Q000627:therapeutic use
chemical_list: D000470:Alkaloids; D047309:Flavones; D008996:Monoamine Oxidase Inhibitors; D010936:Plant Extracts; D008995:Monoamine Oxidase