title: [Microscopic investigation of vessel wall after endovascular catheter atherectomy].
abstract: Endovascular target catheter atherectomy (ETCA) - method of artery patency allowing to obtain occlusion substrate. Given the high destructive effect of atherectome's elements on tissue the objective was determination possibility of histological and electron microscopic investigation of this substrate after atherectomy. The research included 8 patients who underwent ETCA of legs arteries. It was observed substrate removal from broken stent in 1 case. 2 of 8 patients had diabetes. Obtained substrate was available for histological and electron microscopic investigation. Atherosclerosis was confirmed in all cases. It was not observed substrate significant morphological changes in patients with presence or absence of diabetes. Microscopic investigation of substrate from broken stent shows pronounced development of granulation tissue that was regarded as special form of reparative regeneration. Finding internal elastic membrane during microscopic investigation in some cases proves radical intervention. The authors consider that microscopic investigation of substrate after ETCA may be used for diagnosis verification, thorough analysis of morphological changes in lesion area and radicalism of atherectomy.
authors.forename: V N
authors.initials: VN
authors.lastname: Tsygankov
authors.forename: R G
authors.initials: RG
authors.lastname: Khovalkin
authors.forename: I A
authors.initials: IA
authors.lastname: Chekmareva
authors.forename: D V
authors.initials: DV
authors.lastname: Kalinin
authors.forename: E M
authors.initials: EM
authors.lastname: Filippova
mesh_terms: D000368:Aged; D001158:Arteries / Q000473:pathology*; D017073:Atherectomy / Q000379:methods*; D050197:Atherosclerosis / Q000150:complications / Q000473:pathology; D005260:Female; D006801:Humans; D035002:Lower Extremity / Q000098:blood supply*; D008297:Male; D008853:Microscopy / Q000379:methods; D058729:Peripheral Arterial Disease / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D016896:Treatment Outcome