title: Antiphospholipid syndrome and acute myocardial infarction: treatment with thrombectomy and abciximab.
abstract: Antiphospholipid syndrome (APS) is an autoimmune coagulation disorder that manifests clinically as venous and arterial thrombosis, and may affect any tissue or organ. Coronary artery involvement, however, is very rare. Case reports in the literature describing patients with coronary acute syndrome and APS treated with coronary angioplasty show conflicting results. We report an adult male patient with APS who presented with an acute myocardial infarction. Given the high risk of thrombosis in these patients, he was treated percutaneously with thrombectomy and abciximab. We review the few cases of coronary angioplasty in patients with APS reported to date. To our knowledge, this is the first case in which acute myocardial infarction due to thrombotic coronary occlusion was treated with thrombectomy and abciximab without stenting the artery.
authors.affiliation: Hospital Santa Creu y San Pau, Barcelona, Spain. Electronic address: VMarti@santpau.cat.
authors.forename: Vicens
authors.initials: V
authors.lastname: Martí
authors.affiliation: Hospital São Bernardo, Centro Hospitalar Setúbal, Setúbal, Portugal.
authors.forename: Filipe
authors.initials: F
authors.lastname: Seixo
authors.affiliation: Hospital Santa Creu y San Pau, Barcelona, Spain.
authors.forename: Miguel
authors.initials: M
authors.lastname: Santaló
authors.affiliation: Hospital Santa Creu y San Pau, Barcelona, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Serra
mesh_terms: D000077284:Abciximab; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D000925:Anticoagulants / Q000627:therapeutic use*; D016736:Antiphospholipid Syndrome / Q000150:complications / Q000628:therapy*; D003131:Combined Modality Therapy; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000628:therapy*; D017131:Thrombectomy
chemical_list: D000911:Antibodies, Monoclonal; D000925:Anticoagulants; D007140:Immunoglobulin Fab Fragments; D000077284:Abciximab
keywords: Abciximab; Acute coronary syndrome; Antiphospholipid syndrome; Síndrome antifosfolipídica; Síndrome coronária aguda; Thrombectomy; Trombectomia