title: An iridoid glucoside and the related aglycones from Cornus florida.
abstract: A new iridoid glucoside, cornusoside A (1), and four new natural product iridoid aglycones, cornolactones A-D (2-5), together with 10 known compounds were isolated from the leaves of Cornus florida. The structures of compounds 1-5 were established by interpretation of their spectroscopic data. Cornolactone B (3) is the first natural cis-fused tricyclic dilactone iridoid containing both a five- and a six-membered lactone ring. A biosynthesis pathway is proposed for cornolactones C (4) and D (5), the C-6 epimers of compounds 1-3.
authors.affiliation: Department of Applied Chemistry, College of Science, Xi'an University of Technology , Xi'an 710054, People's Republic of China.
authors.forename: Yangqing
authors.initials: Y
authors.lastname: He
authors.forename: Jiangnan
authors.initials: J
authors.lastname: Peng
authors.forename: Mark T
authors.initials: MT
authors.lastname: Hamann
authors.forename: Lyndon M
authors.initials: LM
authors.lastname: West
mesh_terms: D029768:Cornus / Q000737:chemistry*; D057888:Iridoid Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D039823:Iridoids / Q000737:chemistry / Q000302:isolation & purification*; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification*; D008922:Mississippi; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry
chemical_list: D057888:Iridoid Glucosides; D039823:Iridoids; D007783:Lactones; C000594572:cornusoside A