title: Accuracy of cytotechnologist evaluation of specimen adequacy and screening interpretation of malignancy in fine-needle aspiration of the liver.
abstract: OBJECTIVE
  To evaluate the performance of cytotechnologists in assessing the adequacy and accuracy of the preliminary diagnosis for fine-needle aspirates of the liver.
  
  
  METHODS
  We retrospectively analyzed 10 years of data and found 589 cases of ultrasound-guided fine-needle aspiration (FNA) of the liver with on-site evaluation of adequacy (OSEA). All the OSEA were performed by the cytopathologist because OSEA of liver FNA is not performed by cytotechnologists at our institution at present. After OSEA, the material was seen by cytotechnologists who rendered an adequacy assessment and preliminary diagnosis. We calculated the adequacy and accuracy statistics and compared the performance of the cytotechnologists with the OSEA and final interpretation.
  
  
  RESULTS
  There was no statistically significant difference in adequacy downgrade rate for cytotechnologist versus cytopathologist assessment during the study period (5 vs. 3%, p = 0.06). A total agreement of 88% was noted in overall diagnosis with 97% agreement in malignant cases.
  
  
  CONCLUSIONS
  Cytotechnologists assess the adequacy of liver FNA accurately and there is therefore potential for them to perform OSEA for liver FNA.
authors.affiliation: Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Md., USA.
authors.forename: Aadil
authors.initials: A
authors.lastname: Ahmed
authors.forename: Anna B
authors.initials: AB
authors.lastname: Novak
authors.forename: Aisha
authors.initials: A
authors.lastname: Farhat Sheerin
authors.forename: Thiraphon
authors.initials: T
authors.lastname: Boonyaarunnate
authors.forename: Syed Z
authors.initials: SZ
authors.lastname: Ali
authors.forename: Matthew T
authors.initials: MT
authors.lastname: Olson
mesh_terms: D000328:Adult; D000368:Aged; D015142:Baltimore; D044963:Biopsy, Fine-Needle / Q000592:standards*; D002983:Clinical Competence / Q000592:standards*; D016208:Databases, Factual; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000145:classification / Q000473:pathology*; D008297:Male; D017056:Medical Laboratory Personnel / Q000592:standards*; D008875:Middle Aged; D009367:Neoplasm Staging; D015588:Observer Variation; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012189:Retrospective Studies; D013647:Task Performance and Analysis