title: Lipid interactions during virus entry and infection.
abstract: For entry and infection viruses have developed numerous strategies to subjugate indispensable cellular factors and functions. Host cell lipids and cellular lipid synthesis machinery are no exception. Not only do viruses exploit existing lipid signalling and modifications for virus entry and trafficking, they also reprogram lipid synthesis, metabolism, and compartmentalization for assembly and egress. Here we review these various concepts and highlight recent progress in understanding viral interactions with host cell lipids during entry and assembly.
authors.affiliation: MRC-Laboratory for Molecular Cell Biology, University College London, Gower Street, London, WC1E 6BT, UK.
authors.forename: Michela
authors.initials: M
authors.lastname: Mazzon
authors.forename: Jason
authors.initials: J
authors.lastname: Mercer
mesh_terms: D002462:Cell Membrane / Q000821:virology*; D054884:Host-Pathogen Interactions / Q000502:physiology*; D006801:Humans; D050356:Lipid Metabolism / Q000502:physiology*; D008563:Membrane Lipids / Q000378:metabolism*; D015398:Signal Transduction; D014777:Virus Diseases / Q000378:metabolism; D053586:Virus Internalization; D014779:Virus Replication
chemical_list: D008563:Membrane Lipids