title: Short- and long-term outcomes of every graft recovered during a multi-organ procurement procedure including the intestine.
abstract: BACKGROUND
  The development of intestinal transplant (Tx) programs introduces thymoglobulin donor treatment as well as an almost complete warm dissection of the abdominal organs to allocate them to different recipients. Our aim is to assess the reproducibility and feasibility of the surgical technique of multi-organ procurement with the use of thymoglobulin donor pre-treatment and report the short- and long-term outcomes of every graft harvested as part of multi-organ procurement (MTOp), including the intestine.
  
  
  METHODS
  Data were collected of all organs harvested from MTOp, including the intestines allocated to our center from March 2006 to July 2011. Data from 92 recipients and 116 organs procured from 29 MTOp were analyzed. Twelve hearts, 2 lungs, and 1 cardio-pulmonary block were transplanted; primary graft dysfunction developed in 4 of the 12 hearts and in the cardio-pulmonary block.
  
  
  RESULTS
  The survival rate was 75% and 100% for hearts and lungs, respectively. Nineteen livers, 9 kidney-pancreas, 19 kidneys, and 29 intestines were transplanted. Delayed graft function (DGF) of the pancreas developed in 3 of 9 kidney-pancreas, and the other 3 exhibited DGF of the kidney; 4 of 19 Tx kidneys had DGF. The survival was 84%, 78%, 95%, and 65.5% for livers, kidney-pancreas, kidneys, and intestines, respectively.
  
  
  CONCLUSIONS
  Organs procured during MTOp including the intestine can be safely used, increasing organ availability and transplant applicability without compromising allocation, quality, and long-term results of the non-intestinal-procured organs.
authors.affiliation: Hospital Universitario Fundación Favaloro. Electronic address: pablofarinelli@hotmail.com.
authors.forename: P A
authors.initials: PA
authors.lastname: Farinelli
authors.affiliation: Hospital Universitario Fundación Favaloro.
authors.forename: J M
authors.initials: JM
authors.lastname: Padin
authors.affiliation: Instituto Nacional Central Único Coordinador de Ablación e Implante (INCUCAI).
authors.forename: J C
authors.initials: JC
authors.lastname: Troncoso
authors.affiliation: Hospital Universitario Fundación Favaloro.
authors.forename: A
authors.initials: A
authors.lastname: Bertolotti
authors.affiliation: Hospital Italiano de Buenos Aires.
authors.forename: M
authors.initials: M
authors.lastname: Lenz
authors.affiliation: Instituto de Nefrología Nephrology S.A.
authors.forename: N
authors.initials: N
authors.lastname: Sanchez
authors.affiliation: Hospital Universitario Fundación Favaloro.
authors.forename: R
authors.initials: R
authors.lastname: Fortunato
authors.affiliation: Hospital Italiano de Buenos Aires.
authors.forename: E
authors.initials: E
authors.lastname: Caravello
authors.affiliation: Hospital Italiano de Buenos Aires.
authors.forename: N
authors.initials: N
authors.lastname: Imperiali
authors.affiliation: Hospital de Pediatría SAMIC Prof. Dr. Juan Pedro Garrahan.
authors.forename: M
authors.initials: M
authors.lastname: Dip
authors.affiliation: Hospital Italiano de Buenos Aires.
authors.forename: R
authors.initials: R
authors.lastname: Sanchez Claria
authors.affiliation: Clínica de Nefrología, Urología y Enfermedades Cardiovasculares de la Ciudad de Santa Fe SA.
authors.forename: M
authors.initials: M
authors.lastname: Arriola
authors.affiliation: Hospital Privado de Córdoba.
authors.forename: J
authors.initials: J
authors.lastname: De Arteaga
authors.affiliation: Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno" (CEMIC).
authors.forename: G
authors.initials: G
authors.lastname: Pujol Soler
authors.affiliation: Instituto Nacional Central Único Coordinador de Ablación e Implante (INCUCAI).
authors.forename: L
authors.initials: L
authors.lastname: Bisigniano
authors.affiliation: Hospital Allende.
authors.forename: O
authors.initials: O
authors.lastname: Gil
authors.affiliation: Hospital Alemán.
authors.forename: L
authors.initials: L
authors.lastname: McCormack
authors.affiliation: Clínica de Nefrología, Urología y Enfermedades Cardiovasculares de la Ciudad de Santa Fe SA.
authors.forename: E
authors.initials: E
authors.lastname: Botta
authors.affiliation: Hospital General de Agudos "Dr. Cosme Argerich"
authors.forename: O
authors.initials: O
authors.lastname: Inventarza
authors.affiliation: Clínica de Nefrología, Urología y Enfermedades Cardiovasculares de la Ciudad de Santa Fe SA.
authors.forename: L
authors.initials: L
authors.lastname: Gaite
authors.affiliation: Hospital Italiano de Buenos Aires.
authors.forename: S H
authors.initials: SH
authors.lastname: Hyon
authors.affiliation: Hospital Universitario Fundación Favaloro.
authors.forename: P
authors.initials: P
authors.lastname: Raffaele
authors.affiliation: Instituto de Nefrología Nephrology S.A.
authors.forename: G
authors.initials: G
authors.lastname: Illanes
authors.affiliation: Hospital Italiano de Buenos Aires.
authors.forename: E
authors.initials: E
authors.lastname: de Santibañez
authors.affiliation: Hospital Universitario Fundación Favaloro.
authors.forename: R
authors.initials: R
authors.lastname: Favaloro
authors.affiliation: Hospital Universitario Fundación Favaloro.
authors.forename: G
authors.initials: G
authors.lastname: Gondolesi
mesh_terms: D000293:Adolescent; D000328:Adult; D000961:Antilymphocyte Serum; D002648:Child; D002675:Child, Preschool; D005240:Feasibility Studies; D005260:Female; D006085:Graft Survival; D006801:Humans; D007223:Infant; D007422:Intestines / Q000637:transplantation; D008297:Male; D016377:Organ Transplantation; D015203:Reproducibility of Results; D012189:Retrospective Studies; D015996:Survival Rate; D020858:Tissue and Organ Harvesting / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D009927:Tissue and Organ Procurement; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000961:Antilymphocyte Serum; C512542:thymoglobulin