title: Enzymatic size control of RNA particles using complementary rolling circle transcription (cRCT) method for efficient siRNA production.
abstract: A novel fabrication method for RNA particles (RPs) was developed based on enzymatic polymerization, and the size of the RPs was controlled intentionally by adjusting the RNA polymerase concentration for a variety of potential applications.
authors.affiliation: Department of Chemical Engineering, University of Seoul, Seoul, 130-743, South Korea. jblee@uos.ac.kr.
authors.forename: Daehoon
authors.initials: D
authors.lastname: Han
authors.forename: Yongkuk
authors.initials: Y
authors.lastname: Park
authors.forename: Hyangsu
authors.initials: H
authors.lastname: Nam
authors.forename: Jong Bum
authors.initials: JB
authors.lastname: Lee
mesh_terms: D004270:DNA, Circular / Q000737:chemistry*; D012321:DNA-Directed RNA Polymerases / Q000737:chemistry*; D021141:Nucleic Acid Amplification Techniques; D012313:RNA / Q000737:chemistry*; D043244:Ribonuclease III / Q000737:chemistry; D014158:Transcription, Genetic
chemical_list: D004270:DNA, Circular; D012313:RNA; D012321:DNA-Directed RNA Polymerases; D043244:Ribonuclease III