title: A selective and sensitive fluorescent albumin probe for the determination of urinary albumin.
abstract: In this communication, we report a simple albumin probe based on a fluorescent molecular rotor for the detection of trace albumin levels in urine. In the presence of albumin, the probe exhibits remarkable 400-fold fluorescence enhancement with high selectivity and sensitivity. The probe was successfully applied in the quantitative detection of urinary albumin.
authors.affiliation: Department of Chemistry, National Tsing Hua University, 101 Sec. 2, Kuang Fu Rd, Hsinchu 30013, Taiwan, Republic of China. kttan@mx.nthu.edu.tw.
authors.forename: Ying-Yi
authors.initials: YY
authors.lastname: Wu
authors.forename: Wan-Ting
authors.initials: WT
authors.lastname: Yu
authors.forename: Tai-Cheng
authors.initials: TC
authors.lastname: Hou
authors.forename: Tao-Kai
authors.initials: TK
authors.lastname: Liu
authors.forename: Chi-Ling
authors.initials: CL
authors.lastname: Huang
authors.forename: I-Chia
authors.initials: IC
authors.lastname: Chen
authors.forename: Kui-Thong
authors.initials: KT
authors.lastname: Tan
mesh_terms: D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D011485:Protein Binding; D012709:Serum Albumin / Q000032:analysis*; D013050:Spectrometry, Fluorescence
chemical_list: D005456:Fluorescent Dyes; D012709:Serum Albumin