title: Nordic guidelines 2014 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms.
abstract: The diagnostic work-up and treatment of patients with neuroendocrine neoplasms (NENs) has undergone major recent advances and new methods are currently introduced into the clinic. An update of the WHO classification has resulted in a new nomenclature dividing NENs into neuroendocrine tumours (NETs) including G1 (Ki67 index ≤ 2%) and G2 (Ki67 index 3-20%) tumours and neuroendocrine carcinomas (NECs) with Ki67 index > 20%, G3. Aim. These Nordic guidelines summarise the Nordic Neuroendocrine Tumour Group's current view on how to diagnose and treat NEN-patients and are meant to be useful in the daily practice for clinicians handling these patients.
authors.affiliation: Department of Medical Sciences, Uppsala University , Uppsala , Sweden *
authors.forename: Eva Tiensuu
authors.initials: ET
authors.lastname: Janson
authors.forename: Halfdan
authors.initials: H
authors.lastname: Sorbye
authors.forename: Staffan
authors.initials: S
authors.lastname: Welin
authors.forename: Birgitte
authors.initials: B
authors.lastname: Federspiel
authors.forename: Henning
authors.initials: H
authors.lastname: Grønbæk
authors.forename: Per
authors.initials: P
authors.lastname: Hellman
authors.forename: Morten
authors.initials: M
authors.lastname: Ladekarl
authors.forename: Seppo W
authors.initials: SW
authors.lastname: Langer
authors.forename: Jann
authors.initials: J
authors.lastname: Mortensen
authors.forename: Camilla
authors.initials: C
authors.lastname: Schalin-Jäntti
authors.forename: Anders
authors.initials: A
authors.lastname: Sundin
authors.forename: Anna
authors.initials: A
authors.lastname: Sundlöv
authors.forename: Espen
authors.initials: E
authors.lastname: Thiis-Evensen
authors.forename: Ulrich
authors.initials: U
authors.lastname: Knigge
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D018278:Carcinoma, Neuroendocrine / Q000737:chemistry / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000628:therapy; D003952:Diagnostic Imaging / Q000379:methods; D005770:Gastrointestinal Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000628:therapy; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000628:therapy; D018358:Neuroendocrine Tumors / Q000737:chemistry / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000628:therapy; D010190:Pancreatic Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000628:therapy; D011379:Prognosis
chemical_list: D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor