title: Double-valve replacement for mitral and aortic regurgitation in a Patient with Libman-Sacks endocarditis.
abstract: A 53-year-old woman with systemic lupus erythematosus and antiphospholipid syndrome presented with central nervous system (CNS) lupus and vegetation of the mitral and aortic valves. Her CNS lupus was relieved with methylprednisolone pulse therapy; however, her mitral regurgitation worsened, and she developed acute decompensated heart failure. The mitral and aortic valves were replaced with mechanical heart valves. Microscopic examination of the excised valves showed no bacterial invasion, and Libman-Sacks (LS) endocarditis of both valves was confirmed. This was a case of LS endocarditis with clear vegetation that spread over the mitral and aortic valves.
authors.affiliation: Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Japan.
authors.forename: Kenta
authors.initials: K
authors.lastname: Hachiya
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Wakami
authors.forename: Tomomitsu
authors.initials: T
authors.lastname: Tani
authors.forename: Atsuhiro
authors.initials: A
authors.lastname: Yoshida
authors.forename: Shugo
authors.initials: S
authors.lastname: Suzuki
authors.forename: Hisao
authors.initials: H
authors.lastname: Suda
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Ohte
mesh_terms: D016736:Antiphospholipid Syndrome / Q000150:complications / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000209:etiology / Q000601:surgery*; D005260:Female; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000601:surgery*; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000209:etiology / Q000601:surgery*; D016896:Treatment Outcome