title: Echinocandin-induced eosinophilia: a case report.
abstract: Drug-induced eosinophilia is difficult to diagnose. Severe organ damage can occur if it is left untreated. Presently, caspofungin is the only echinocandin that has been reported to cause eosinophilia. A patient who developed eosinophilia after exposure to caspofungin and re-challenge with anidulafungin is presented. Eosinophilia resolved upon discontinuation of both drugs.
authors.affiliation: From the Department of Pharmacy, Singapore General Hospital , Singapore.
authors.forename: Nathalie G
authors.initials: NG
authors.lastname: Chua
authors.forename: Yvonne P
authors.initials: YP
authors.lastname: Zhou
authors.forename: Pushpalatha B
authors.initials: PB
authors.lastname: Lingegowda
authors.forename: Andrea L
authors.initials: AL
authors.lastname: Kwa
authors.forename: Winnie
authors.initials: W
authors.lastname: Lee
mesh_terms: D000368:Aged; D000077612:Anidulafungin; D000935:Antifungal Agents / Q000009:adverse effects*; D000077336:Caspofungin; D054714:Echinocandins / Q000009:adverse effects*; D004802:Eosinophilia / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D005260:Female; D006801:Humans; D055666:Lipopeptides
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D000077612:Anidulafungin; D000077336:Caspofungin
keywords: Echinocandins; adverse effect; anidulafungin; caspofungin; eosinophilia