title: [Prevalence of hepatitis B infection in children under 5 years old on indigenous communities of the Peruvian Amazonia after immunization interventions].
abstract: OBJECTIVE
  To determine the prevalence of hepatitis B virus (HVB) infection and seroprotection in indigenous children living in three draining basins of the Peruvian Amazon.
  
  
  METHODS
  A cross sectional study was conducted in three draining basins (Pastaza, Morona and Lower Urubamba rivers), home to six indigenous populations: shapra, candoshi, machiguenga, yine, ashaninka and nanti. Children under 5 years were included. A survey and review of the vaccination card was applied, and a serum sample was processed with ELISA for HBsAg, total anti-HBc and anti-HBs was obtained, defining "seroprotected children" if they were reactive to anti-HBs and non-reactive to anti-HBc.
  
  
  RESULTS
  A total of 742 children under 5 years old residents in six indigenous communities were included in the study. 380 (51.2%) were male and 169 (22.9%) one year old or younger. Regarding recorded HVB vaccination on the card, only 434 (58.5%) had received three doses; 208 (38.8%) received the first dose within 24 hours. No cases were detected with HBsAg. 88.8% of children had seroconverted, varying between 67-100% across the populations.
  
  
  CONCLUSIONS
  No cases of chronic HBV infection were detected. The vaccination coverage by card revision is low, contrasting with high seroconversion rates.
authors.affiliation: Centro Nacional de Salud Pública, Instituto Nacional de Salud, Lima, Perú
authors.forename: César
authors.initials: C
authors.lastname: Cabezas-Sánchez
authors.affiliation: Centro Nacional de Salud Intercultural, Instituto Nacional de Salud, Lima, Perú
authors.forename: Omar
authors.initials: O
authors.lastname: Trujillo-Villarroel
authors.affiliation: Centro Nacional de Salud Intercultural, Instituto Nacional de Salud, Lima, Perú
authors.forename: Carol
authors.initials: C
authors.lastname: Zavaleta-Cortijo
authors.affiliation: Centro Nacional de Salud Intercultural, Instituto Nacional de Salud, Lima, Perú
authors.forename: Dante
authors.initials: D
authors.lastname: Culqui-Lévano
authors.affiliation: Centro Nacional de Salud Pública, Instituto Nacional de Salud, Lima, Perú
authors.forename: Magna
authors.initials: M
authors.lastname: Suarez-Jara
authors.affiliation: Centro Nacional de Salud Intercultural, Instituto Nacional de Salud, Lima, Perú
authors.forename: Neptalí
authors.initials: N
authors.lastname: Cueva-Maza
authors.affiliation: Centro Nacional de Salud Intercultural, Instituto Nacional de Salud, Lima, Perú
authors.forename: Shirley
authors.initials: S
authors.lastname: Monzon
mesh_terms: D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology* / Q000517:prevention & control*; D017325:Hepatitis B Vaccines; D006801:Humans; D007114:Immunization; D007199:Indians, South American; D007223:Infant; D008297:Male; D010568:Peru; D015995:Prevalence
chemical_list: D017325:Hepatitis B Vaccines