title: Trends in antifungal susceptibility of Candida species--one year observation.
abstract: In the past years opportunistic fungal infections have seriously increased, mainly in immunocompromised patients. The aim of the study was to determine the prevalence of yeast-like fungi in invasive candidiasis and to estimate its susceptibility to chosen antifungal agents. One hundred and sixty strains of yeast-like fungi were cultured from various clinical material: samples from lower respiratory tract, blood, the peritoneal cavity and others. The susceptibility tests were established according to the quantitative E-test method. The Candida genus represented the main etiological factor of invasive candidiasis. The predominant species were: C. glabrata (71/160), C. albicans (34/160), C. krusei (17/160), C. tropicalis (14/160). All tested strains were the most resistant to itraconazole. Candida glabrata presented the 100% susceptibility to amphotericin B and caspofungin and was the least susceptible to itraconazole, posaconazole and voriconazole. Candida albicans was the most susceptible species to all antymicotics.
authors.forename: M
authors.initials: M
authors.lastname: Gołaś
authors.forename: I
authors.initials: I
authors.lastname: Netsvyetayeva
authors.forename: M
authors.initials: M
authors.lastname: Sikora
authors.forename: K
authors.initials: K
authors.lastname: Piskorska
authors.forename: B
authors.initials: B
authors.lastname: Sulik-Tyszka
authors.forename: E
authors.initials: E
authors.lastname: Swoboda-Kopeć
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000145:classification / Q000187:drug effects*; D058365:Candidiasis, Invasive / Q000382:microbiology*; D025141:Drug Resistance, Fungal; D006801:Humans; D008826:Microbial Sensitivity Tests
chemical_list: D000935:Antifungal Agents