title: [The clinical analysis for the whole-spine magnetic resonance imaging of axial spondyloarthritis].
abstract: OBJECTIVE
  To investigate spinemagnetic resonance imaging(MRI) findings in patients with axial spondyloarthritis (SpA) and to analyze the correlation between imaging and clinical manifestation.
  
  
  METHODS
  The clinical data of patients with axial SpA were recorded. All patients underwent whole spine MRI scanning. The MRI findings of spinal involvement were explored. Moreover, the correlation between lesions in spinal MRI and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Metrology Index (BASMI), nocturnal pain visual analogue scale (VAS) score, back pain VAS score, global disease activity VAS score, Ankylosing Spondylitis Disease Activity score (ASDAS), erythrocyte sedimentation rate, C-reactive protein was analyzed.
  
  
  RESULTS
  Thirty-three patients with axial SpA were included in this study. The image abnormalities of the spine were confirmed in 29 axial SpA patients by MRI, including Romanus lesion, Andersson lesion, the inflammation of facet joints and syndesmophyte. In correlation study, BASMI was positively correlated to the numbers of acute Romanus lesions, chronic Romanus lesions, chronic Andersson lesions and whole spinal lesions(r = 0.440, P < 0.05; r = 0.483, P < 0.05; r = 0.421, P < 0.05; r = 0.589, P < 0.05 respectively). There was a statistically significant correlation between chronic Andersson lesions and BASFI(r = 0.392, P < 0.05). But no significant associations were found between MRI lesions and other clinical findings.
  
  
  CONCLUSIONS
  MRI lesions in axial SpA were associated with findings reflecting the spinal function, which can better guide the clinical treatment.
authors.affiliation: Department of Rheumatology, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Gui
authors.initials: G
authors.lastname: Luo
authors.affiliation: Department of Rheumatology, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Zhao
authors.affiliation: Department of Rheumatology, Chinese PLA General Hospital, Beijing 100853, China. Email: jian.jzhu@gmail.com.
authors.forename: Jian
authors.initials: J
authors.lastname: Zhu
authors.affiliation: Department of Rheumatology, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Jianglin
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Rheumatology, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Huang
mesh_terms: D002097:C-Reactive Protein; D006801:Humans; D007249:Inflammation; D008279:Magnetic Resonance Imaging; D012720:Severity of Illness Index; D025241:Spondylarthritis / Q000175:diagnosis / Q000473:pathology*; D013167:Spondylitis, Ankylosing / Q000175:diagnosis / Q000473:pathology
chemical_list: D002097:C-Reactive Protein