title: An economical and environmentally friendly oxidative biaryl coupling promoted by activated MnO2.
abstract: An activated manganese dioxide (MnO2)-BF3·OEt2 oxidation system was developed to efficiently mediate the intramolecular as well as intermolecular biaryl coupling. The oxidative coupling proceeds smoothly at ambient temperature to deliver the corresponding five- to eight-membered tricyclic products in good to excellent yields. The employment of the combination of MnO2 and BF3·OEt2 is attractive on the basis of economical and environmental issues.
authors.affiliation: Key Lab of Chemical Biology of Ministry of Education, School of Pharmaceutical Sciences, Jinan 250012, P. R. China. leiliu@sdu.edu.cn.
authors.forename: Jingjing
authors.initials: J
authors.lastname: Yang
authors.forename: Shutao
authors.initials: S
authors.lastname: Sun
authors.forename: Ziyu
authors.initials: Z
authors.lastname: Zeng
authors.forename: Hongbo
authors.initials: H
authors.lastname: Zheng
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Hongxiang
authors.initials: H
authors.lastname: Lou
authors.forename: Lei
authors.initials: L
authors.lastname: Liu
mesh_terms: D001554:Benzene / Q000737:chemistry; D055772:Green Chemistry Technology; D017895:Manganese Compounds / Q000737:chemistry*; D058451:Oxidative Coupling; D010087:Oxides / Q000737:chemistry*; D013696:Temperature
chemical_list: D017895:Manganese Compounds; D010087:Oxides; D001554:Benzene; C016552:manganese dioxide