title: Sorptive capacity of membrane lipids, storage lipids, and proteins: a preliminary study of partitioning of organochlorines in lean fish from a PCB-contaminated freshwater lake.
abstract: Knowledge on the internal distribution of halogenated organic chemicals (HOCs) would improve our understanding of dose-effect relationships and subsequently improve risk assessment of contaminated sites. Herein, we determine the concentrations of HOCs based on equilibrium partitioning in storage lipids, membrane lipids, and proteins in field-contaminated fish using equilibrium sampling devices. The study shows the importance of protein as a sorptive phase in lean fish. Our results provide a basis for using species-specific equilibrium partitioning coefficients between sorptive tissues and fish internal water as a substitute for K(ow) in, for example, upgrading models that simulate food-chain accumulation of the chemical.
authors.affiliation: Department of Biology, University of Eastern Finland, P.O. Box 111, FI-80101, Joensuu, Finland, kimmo.maenpaa@uef.fi.
authors.forename: Kimmo
authors.initials: K
authors.lastname: Mäenpää
authors.forename: Matti T
authors.initials: MT
authors.lastname: Leppänen
authors.forename: Kaisa
authors.initials: K
authors.lastname: Figueiredo
authors.forename: Feven
authors.initials: F
authors.lastname: Tigistu-Sahle
authors.forename: Reijo
authors.initials: R
authors.lastname: Käkelä
mesh_terms: D000818:Animals; D029941:Fish Proteins / Q000378:metabolism*; D005399:Fishes / Q000378:metabolism*; D006843:Hydrocarbons, Chlorinated / Q000378:metabolism*; D060106:Lakes / Q000737:chemistry; D008563:Membrane Lipids / Q000378:metabolism*; D011078:Polychlorinated Biphenyls / Q000378:metabolism; D014874:Water Pollutants, Chemical / Q000378:metabolism*
chemical_list: D029941:Fish Proteins; D006843:Hydrocarbons, Chlorinated; D008563:Membrane Lipids; D014874:Water Pollutants, Chemical; D011078:Polychlorinated Biphenyls