title: Solitary Fibrous Tumor With Myxoid Stromal Change.
abstract: We report the case of a 46-year-old Korean woman who presented with a 5-month history of a hyperkeratotic plaque on the left palm. On examination, the plaque showed an annular pattern with an umbilicated central nodule and a peripheral palisading induration, which had a verrucous surface. After surgical resection, histopathologic analysis revealed that the tumor was composed of haphazardly arranged spindle cells and displayed a predominantly myxoid appearance in the stroma. The tumor cells were positive for CD34 and bcl-2, but negative for smooth muscle actin and S-100. The clinical manifestation and histopathologic findings were most consistent with a diagnosis of solitary fibrous tumor with myxoid stromal change. There was no evidence of recurrence or metastasis during the 8-month follow-up period. This case highlights the importance of an accurate diagnosis of solitary fibrous tumors, which may have extensive myxoid stromal change, hence mimicking other myxoid-type spindle cell tumors.
authors.affiliation: *Department of Dermatology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea; and †Department of Dermatology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
authors.forename: Jin Yong
authors.initials: JY
authors.lastname: Lee
authors.forename: So Eun
authors.initials: SE
authors.lastname: Park
authors.forename: Soo Jung
authors.initials: SJ
authors.lastname: Shin
authors.forename: Chul Woo
authors.initials: CW
authors.lastname: Kim
authors.forename: Sang Seok
authors.initials: SS
authors.lastname: Kim
authors.forename: Kwang Ho
authors.initials: KH
authors.lastname: Kim
mesh_terms: D005260:Female; D006225:Hand; D006801:Humans; D008875:Middle Aged; D012878:Skin Neoplasms / Q000473:pathology*; D054364:Solitary Fibrous Tumors / Q000473:pathology*; D017154:Stromal Cells / Q000473:pathology*