title: A case with pachyonychia congenita and B-cell lymphoma.
abstract: Pachyonychia congenital (PC) is a rare autosomal dominant genodermatosis characterized hyperkeratosis affecting the nails and palmoplantar areas, oral leukokeratosis, and cystic lesions. A 39-year-old woman with PC type 1 (Jadassohn-Lewandowsky syndrome) and B-cell lymphoma is described. No similar disorders or parental consanguinity were found in her family. Typical features of PC developed since her early childhood and the diagnosis of B-cell lymphoma was established seven years ago, without a clear causal relation between these entities. Despite inherent limitations of a single case, this report may contribute to PC understanding.
authors.affiliation: Catholic University Medical Course, Brasília-DF, Brazil . AND Department of Internal Medicine, Armed Forces Hospital, Brasília-DF, Brazil. vitorinomodesto@gmail.com.
authors.forename: Vitorino Modesto
authors.initials: VM
authors.lastname: dos Santos
authors.affiliation: Department of Internal Medicine, Armed Forces Hospital, Brasília-DF, Brazil. tloures@hotmail.com.
authors.forename: Thiago Pereira
authors.initials: TP
authors.lastname: Loures
authors.affiliation: Division of Pneumology, Armed Forces Hospital, Brasília-DF, Brazil. sbdt@terra.com.br.
authors.forename: João Daniel Bringel
authors.initials: JD
authors.lastname: Rego
authors.affiliation: Division of Pneumology, Armed Forces Hospital, Brasília-DF, Brazil. chrisateixeira@hotmail.com.
authors.forename: Christiane Aires
authors.initials: CA
authors.lastname: Teixeira
authors.affiliation: Department of Internal Medicine, Armed Forces Hospital, Brasília-DF, Brazil. kayursula.dantas@gmail.com.
authors.forename: Kayursula Dantas
authors.initials: KD
authors.lastname: de Carvalho
authors.affiliation: Department of Internal Medicine, Armed Forces Hospital, Brasília-DF, Brazil. afonso.lon@hotmail.com.
authors.forename: Afonso Lucas Oliveira
authors.initials: AL
authors.lastname: Nascimento
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D053549:Pachyonychia Congenita / Q000150:complications* / Q000175:diagnosis; D014057:Tomography, X-Ray Computed