title: Molecular encapsulation beyond the aperture size limit through dissociative linker exchange in metal-organic framework crystals.
abstract: Under linker exchange conditions, large guests with molecular diameters 3-4 times the framework aperture size have been encapsulated into preformed nanocrystals of the metal-organic framework ZIF-8. Guest encapsulation is facilitated by the formation of short-lived "open" states of the pores upon linker dissociation. Kinetic studies suggested that linker exchange reactions in ZIF-8 proceed via a competition between dissociative and associative exchange mechanisms, and guest encapsulation was enhanced under conditions where the dissociative pathway predominates.
authors.affiliation: Department of Chemistry, Merkert Chemistry Center, Boston College , Chestnut Hill, Massachusetts 02467, United States.
authors.forename: Joseph V
authors.initials: JV
authors.lastname: Morabito
authors.forename: Lien-Yang
authors.initials: LY
authors.lastname: Chou
authors.forename: Zhehui
authors.initials: Z
authors.lastname: Li
authors.forename: Cesar M
authors.initials: CM
authors.lastname: Manna
authors.forename: Christopher A
authors.initials: CA
authors.lastname: Petroff
authors.forename: Rutvin J
authors.initials: RJ
authors.lastname: Kyada
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Palomba
authors.forename: Jeffery A
authors.initials: JA
authors.lastname: Byers
authors.forename: Chia-Kuang
authors.initials: CK
authors.lastname: Tsung