title: Radiologically determined orthodontically induced external apical root resorption in incisors after non-surgical orthodontic treatment of class II division 1 malocclusion: a systematic review.
abstract: This study aims to critically evaluate orthodontically induced external apical root resorption (OIEARR) in incisors of patients undergoing non-surgical orthodontic treatment of class II division 1 malocclusion by a systematic review of the published data. An electronic search of two databases was performed; the bibliographies of relevant articles were also reviewed. Studies were included if they examined the amount of OIEARR in incisors produced during non-surgical orthodontic treatment of individuals with class II division I malocclusion in the permanent dentition. Individuals had no previous history of OIEARR, syndromes, pathologies, or general diseases. Study selections, risk of bias assessment, and data extraction were performed in duplicate. Eight studies of moderate methodological quality were finally included. An increased prevalence (65.6% to 98.1%) and mild to moderate severity of OIEARR (<4 mm and <1/3 original root) were reported. No sex difference in root resorption was found. For the maxillary incisors, there was no evidence that either the central or lateral incisor was more susceptible to OIEARR. A weak to moderate positive correlation between treatment duration and root resorption, and anteroposterior apical displacement and root resorption was found. Current limited evidence suggests that non-surgical comprehensive orthodontic treatment to correct class II division 1 malocclusions causes increased prevalence and severity of OIEARR the more the incisor roots are displaced and the longer this movement takes.
authors.forename: Long D
authors.initials: LD
authors.lastname: Tieu
authors.forename: Humam
authors.initials: H
authors.lastname: Saltaji
authors.forename: David
authors.initials: D
authors.lastname: Normando
authors.affiliation: School of Dentistry, University of Alberta, Edmonton T6G 1C9, Alberta, Canada. cf1@ualberta.ca.
authors.forename: Carlos
authors.initials: C
authors.lastname: Flores-Mir
mesh_terms: D006801:Humans; D007180:Incisor / Q000000981:diagnostic imaging*; D008312:Malocclusion, Angle Class II / Q000628:therapy*; D008334:Mandible / Q000000981:diagnostic imaging; D008437:Maxilla / Q000000981:diagnostic imaging; D009971:Orthodontics, Corrective / Q000009:adverse effects*; D011859:Radiography; D012391:Root Resorption / Q000000981:diagnostic imaging / Q000209:etiology*