title: Alcoholic liver disease complicated by deep bleeding into the muscles or retroperitoneum: report of three cases and a review of the literature.
abstract: We herein report three cases of alcoholic cirrhosis complicated by deep bleeding. In two of the three cases, intramuscular or retroperitoneal hematomas developed spontaneously. In contrast, in the remaining case, an intramuscular hematoma developed after trauma. In the former two patients, the intramuscular hematomas recurred at other sites during hospitalization. All three patients received conservative therapy, and one patient with a retroperitoneal hematoma underwent transcatheter arterial embolization. All of the patients eventually died of liver failure. The occurrence of severe alcoholic liver disease with deep bleeding has recently been reported with increasing frequency, and clinicians should bear this condition in mind as a life-threatening complication of alcoholic liver disease.
authors.affiliation: Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, Japan.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Takamura
authors.forename: Jun
authors.initials: J
authors.lastname: Watanabe
authors.forename: Akira
authors.initials: A
authors.lastname: Sakamaki
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Honda
authors.forename: Kenya
authors.initials: K
authors.lastname: Kamimura
authors.forename: Atsunori
authors.initials: A
authors.lastname: Tsuchiya
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yamagiwa
authors.forename: Takeshi
authors.initials: T
authors.lastname: Suda
authors.forename: Yasunobu
authors.initials: Y
authors.lastname: Matsuda
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Aoyagi
mesh_terms: D000328:Adult; D017809:Fatal Outcome; D005260:Female; D006406:Hematoma / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D006470:Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D011859:Radiography; D012187:Retroperitoneal Space / Q000098:blood supply / Q000473:pathology