title: Evaluation of functional status, pulmonary capacity, body composition, and quality of life of end-stage liver disease patients who are candidates for liver surgery.
abstract: BACKGROUND
  Muscular weakness in combination with malnutrition can induce a global motor impairment and physical inactivity, adversely impairing the daily living activities and quality of life of end-stage liver disease patients who are candidates for liver transplantation.
  
  
  OBJECTIVE
  To evaluate functional status, pulmonary capacity, body composition and quality of life in end-stage liver disease patients who are candidates for liver transplantation; to verify if there is a correlation between the functional variables of the individuals tested through the 6-minute walk test (6MWT) and covariables: pulmonary function test (PFP), quality of life and body composition.
  
  
  METHODS
  This study was carried out at the Liver Transplantation Unit of the State University of Campinas (UNICAMP). We included 46 patients with end-stage liver disease who underwent the following evaluations: medical history, quality of life questionnaire "Short Form 36" (SF-36), surface electromyography (sEMG) of the diaphragm and rectus abdominis muscles, body composition assessment by electrical vioimpedance (BIA), 6MWT and PFP.
  
  
  RESULTS
  Univariate analysis and Pearson's correlation found correlations between distance walked on 6MWT and QOL (P = .006 and P = .02) and TBW (P = .5 and P = .02). Pearson's correlation were found between respiratory variables of 6MWT, QOL, and PFP.
  
  
  CONCLUSIONS
  The functional status may be correlated to body composition, quality of life and pulmonary capacity of patients with liver disease, candidates for transplantation.
authors.affiliation: Faculty of Medical Science, State University of Campinas, Campinas, Brazil.
authors.forename: D C
authors.initials: DC
authors.lastname: dos Santos
authors.affiliation: Faculty of Medical Science, State University of Campinas, Campinas, Brazil.
authors.forename: V
authors.initials: V
authors.lastname: Limongi
authors.affiliation: Faculty of Medical Science, State University of Campinas, Campinas, Brazil.
authors.forename: A M
authors.initials: AM
authors.lastname: de Oliveira da Silva
authors.affiliation: Clinical Hospital, State University of Campinas, Campinas, Brazil.
authors.forename: E C
authors.initials: EC
authors.lastname: de Ataide
authors.affiliation: Clinical Hospital, State University of Campinas, Campinas, Brazil.
authors.forename: M F
authors.initials: MF
authors.lastname: Trovato Mei
authors.affiliation: Clinical Hospital, State University of Campinas, Campinas, Brazil.
authors.forename: E Y
authors.initials: EY
authors.lastname: Udo
authors.affiliation: State University of Campinas, Campinas, Brazil.
authors.forename: I F S F
authors.initials: IF
authors.lastname: Boin
authors.affiliation: State University of Campinas, Campinas, Brazil. Electronic address: stucchi.raquel@gmail.com.
authors.forename: R S B
authors.initials: RS
authors.lastname: Stucchi
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D001823:Body Composition; D004576:Electromyography; D058625:End Stage Liver Disease / Q000503:physiopathology* / Q000601:surgery; D005080:Exercise Test; D005260:Female; D006801:Humans; D016031:Liver Transplantation; D008168:Lung / Q000503:physiopathology*; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength; D011446:Prospective Studies; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016138:Walking