title: Correlation of coronary artery stenosis evaluation with left heart structure and function by multi-slice computed tomography.
abstract: The aim of this study was to determine the impact of multi-slice computed tomography (MSCT) evaluation of coronary artery stenosis on left heart structure and systolic function. Coronary artery CT angiography was performed in 200 patients diagnosed with coronary heart disease, and then according to the AHA coronary artery 17-segment fractionation method, the Gensini score (GS) was determined for every narrow segment, and one-stop assessment of the correlation between left heart structure and function was performed. After the grouping of GS quartiles from low to high, there were differences between different patients with regard to LVDD, LADD, LVEDV, LVESV, MM, LVEF, and FS, while no difference in SV and CO. GS showed linear negative correlation with LVEF and FS, and linear positive correlation with LVDD, LADD, LVEDV, LVESV, and MM, while no correlation with SV and CO. That is, GS of coronary artery stenosis was negatively correlated with left ventricular systolic function and positively correlated with myocardial mass. The narrower the coronary artery, the worse the cardiac function and the higher the myocardial hypertrophy. Coronary artery stenosis was one of the important causes of the decrease in left ventricular systolic function and cardiac remodeling.
authors.affiliation: Department of Radiology, The First Affiliated Hospital of Liaoning Medical University, Jinzhou, China.
authors.forename: L N
authors.initials: LN
authors.lastname: Song
authors.affiliation: Department of Radiology, The First Affiliated Hospital of Liaoning Medical University, Jinzhou, China.
authors.forename: A D
authors.initials: AD
authors.lastname: Cao
authors.affiliation: Department of Radiology, The First Affiliated Hospital of Liaoning Medical University, Jinzhou, China jhdoccn@126.com.
authors.forename: Y J
authors.initials: YJ
authors.lastname: Niu
authors.affiliation: Department of Radiology, The First Affiliated Hospital of Liaoning Medical University, Jinzhou, China.
authors.forename: N
authors.initials: N
authors.lastname: Liu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000000981:diagnostic imaging* / Q000473:pathology*; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D013318:Stroke Volume; D014057:Tomography, X-Ray Computed / Q000379:methods; D061205:Vascular Calcification / Q000000981:diagnostic imaging; D018487:Ventricular Dysfunction, Left; D016277:Ventricular Function, Left