title: A colorimetric immunoassay for respiratory syncytial virus detection based on gold nanoparticles-graphene oxide hybrids with mercury-enhanced peroxidase-like activity.
abstract: A novel colorimetric immunoassay for highly sensitive detection of respiratory syncytial virus (RSV), one of the leading causes of severe lower respiratory tract infections in all age groups, has been proposed based on Hg(2+)-stimulated peroxidase-like activity of gold nanoparticles-graphene oxide (AuNPs-GO) hybrids. This metal ion-enhanced immunoassay shows high promise in the field of biomedical sciences.
authors.affiliation: Key Laboratory on Luminescence and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China. chengzhi@swu.edu.cn.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhan
authors.forename: Chun Mei
authors.initials: CM
authors.lastname: Li
authors.forename: Wen Bi
authors.initials: WB
authors.lastname: Wu
authors.forename: Cheng Zhi
authors.initials: CZ
authors.lastname: Huang
mesh_terms: D000906:Antibodies / Q000737:chemistry / Q000276:immunology; D003124:Colorimetry; D006046:Gold / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry*; D007118:Immunoassay; D008628:Mercury / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry; D010544:Peroxidases / Q000737:chemistry / Q000378:metabolism; D012136:Respiratory Syncytial Viruses / Q000276:immunology / Q000302:isolation & purification*
chemical_list: D000906:Antibodies; D010087:Oxides; D006046:Gold; D006108:Graphite; D010544:Peroxidases; D008628:Mercury