title: Cu(I)-NHC-catalyzed silylation of allenes: diastereoselective three-component coupling with aldehydes.
abstract: Copper-catalyzed silylation of aryl allenes using a silylborane reagent affords vinyl silane building blocks with high efficiency. The use of a seven-membered NHC ligand proved crucial for high regioselectivity. The catalytically generated allylcoppper intermediates were intercepted by aldehydes in a diastereoselective three-component coupling to furnish homoallylic alcohols.
authors.affiliation: School of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL (UK) http://people.man.ac.uk/∼mbdssdp2/
authors.forename: James
authors.initials: J
authors.lastname: Rae
authors.forename: Ya Chu
authors.initials: YC
authors.lastname: Hu
authors.forename: David J
authors.initials: DJ
authors.lastname: Procter
keywords: N-heterocyclic carbenes; allenes; copper; homogeneous catalysis; silylation