title: Severe dermatologic reactions with bendamustine: a case series.
abstract: Cutaneous drug reactions make up the largest proportion of adverse events in the medical field. Causality, in particular, is difficult to determine, and therefore, preventing recurrent reactions can be challenging. Bendamustine was initially thought to be a well-tolerated chemotherapy agent with few side effects aside from bone marrow suppression. However, the incidence of cutaneous reactions reported is rising. We describe three such reactions in relation to bendamustine administration in hopes of adding to the awareness of such side effects.
authors.affiliation: UF Health Cancer Center, Orlando Health, Orlando, Fla., USA.
authors.forename: Allison
authors.initials: A
authors.lastname: Carilli
authors.affiliation: Halifax Regional Oncology Center, Daytona Beach, Fla., USA.
authors.forename: Gregory
authors.initials: G
authors.lastname: Favis
authors.affiliation: Department of Pathology, Orlando Health, Orlando, Fla., USA.
authors.forename: Lohini
authors.initials: L
authors.lastname: Sundharkrishnan
authors.affiliation: UF Health Cancer Center, Orlando Health, Orlando, Fla., USA.
authors.forename: Julio
authors.initials: J
authors.lastname: Hajdenberg
keywords: Adverse events; Bendamustine; Chemotherapy; Dermatologic reaction; Lymphoma; Rash