title: Intraoperative surgical sealant application during cardiac defect repair.
abstract: Bleeding can occur as a sequela to cardiac surgery. Surgical products-such as conventional sutures and clips, and somewhat less conventional sealants-have been developed to prevent this event. Among these, CoSeal is a sealant used at our institution; here we report the cases of 2 patients in whom CoSeal was used successfully as either a supplement or an alternative to suture repair. This sealant was found to be useful in attaining hemostasis both in high-pressure ventricular repair and in the rupture of a friable coronary sinus adjacent to vital structures (in this instance, a left circumflex coronary artery).
authors.affiliation: Department of Cardiovascular Surgery, Methodist DeBakey Heart & Vascular Center, Houston, Texas 77030.
authors.forename: Luis J
authors.initials: LJ
authors.lastname: Garcia-Morales
authors.affiliation: Department of Cardiovascular Surgery, Methodist DeBakey Heart & Vascular Center, Houston, Texas 77030.
authors.forename: Mahesh
authors.initials: M
authors.lastname: Ramchandani
authors.affiliation: Department of Cardiovascular Surgery, Methodist DeBakey Heart & Vascular Center, Houston, Texas 77030.
authors.forename: Matthias
authors.initials: M
authors.lastname: Loebe
authors.affiliation: Department of Cardiovascular Surgery, Methodist DeBakey Heart & Vascular Center, Houston, Texas 77030.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Reardon
authors.affiliation: Department of Cardiovascular Surgery, Methodist DeBakey Heart & Vascular Center, Houston, Texas 77030.
authors.forename: Brian A
authors.initials: BA
authors.lastname: Bruckner
authors.affiliation: Department of Cardiovascular Surgery, Methodist DeBakey Heart & Vascular Center, Houston, Texas 77030.
authors.forename: Basel
authors.initials: B
authors.lastname: Ramlawi
mesh_terms: D016063:Blood Loss, Surgical / Q000517:prevention & control*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D005260:Female; D006331:Heart Diseases / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D006488:Hemostasis, Surgical / Q000379:methods*; D006801:Humans; D008875:Middle Aged; D011092:Polyethylene Glycols / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: C513322:CoSeal; D011092:Polyethylene Glycols
keywords: Anastomosis, surgical/adverse effects/methods; biocompatible materials/therapeutic use; blood loss, surgical/prevention & control; coronary sinus; heart ventricles; heart-assist devices; hemostasis, surgical/methods; polyethylene glycols; vascular surgical procedures/methods