title: Multi-resolution voxel phantom modeling: a high-resolution eye model for computational dosimetry.
abstract: Voxel models of the human body are commonly used for simulating radiation dose with a Monte Carlo radiation transport code. Due to memory limitations, the voxel resolution of these computational phantoms is typically too large to accurately represent the dimensions of small features such as the eye. Recently reduced recommended dose limits to the lens of the eye, which is a radiosensitive tissue with a significant concern for cataract formation, has lent increased importance to understanding the dose to this tissue. A high-resolution eye model is constructed using physiological data for the dimensions of radiosensitive tissues, and combined with an existing set of whole-body models to form a multi-resolution voxel phantom, which is used with the MCNPX code to calculate radiation dose from various exposure types. This phantom provides an accurate representation of the radiation transport through the structures of the eye. Two alternate methods of including a high-resolution eye model within an existing whole-body model are developed. The accuracy and performance of each method is compared against existing computational phantoms.
authors.affiliation: Nuclear Engineering Program, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
authors.forename: Peter F
authors.initials: PF
authors.lastname: Caracappa
authors.forename: Ashley
authors.initials: A
authors.lastname: Rhodes
authors.forename: Derek
authors.initials: D
authors.lastname: Fiedler
mesh_terms: D000465:Algorithms; D002386:Cataract / Q000209:etiology / Q000517:prevention & control; D003198:Computer Simulation; D005123:Eye / Q000528:radiation effects*; D005260:Female; D006801:Humans; D007908:Lens, Crystalline / Q000528:radiation effects*; D008297:Male; D008962:Models, Theoretical; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D011835:Radiation Protection / Q000379:methods; D011874:Radiometry / Q000379:methods*