title: Left atrial volume index and prediction of events in acute coronary syndrome: Solar Registry.
abstract: BACKGROUND
  According to some international studies, patients with acute coronary syndrome (ACS) and increased left atrial volume index (LAVI) have worse long-term prognosis. However, national Brazilian studies confirming this prediction are still lacking.
  
  
  OBJECTIVE
  To evaluate LAVI as a predictor of major cardiovascular events (MCE) in patients with ACS during a 365-day follow-up.
  
  
  METHODS
  Prospective cohort of 171 patients diagnosed with ACS whose LAVI was calculated within 48 hours after hospital admission. According to LAVI, two groups were categorized: normal LAVI (≤ 32 mL/m2) and increased LAVI (> 32 mL/m2). Both groups were compared regarding clinical and echocardiographic characteristics, in- and out-of-hospital outcomes, and occurrence of ECM in up to 365 days.
  
  
  RESULTS
  Increased LAVI was observed in 78 patients (45%), and was associated with older age, higher body mass index, hypertension, history of myocardial infarction and previous angioplasty, and lower creatinine clearance and ejection fraction. During hospitalization, acute pulmonary edema was more frequent in patients with increased LAVI (14.1% vs. 4.3%, p = 0.024). After discharge, the occurrence of combined outcome for MCE was higher (p = 0.001) in the group with increased LAVI (26%) as compared to the normal LAVI group (7%) [RR (95% CI) = 3.46 (1.54-7.73) vs. 0.80 (0.69-0.92)]. After Cox regression, increased LAVI increased the probability of MCE (HR = 3.08, 95% CI = 1.28-7.40, p = 0.012).
  
  
  CONCLUSIONS
  Increased LAVI is an important predictor of MCE in a one-year follow-up.
authors.affiliation: Universidade Federal de Sergipe, Aracaju, SE, Brazil.
authors.forename: Jose Alves
authors.initials: JA
authors.lastname: Secundo Junior
authors.affiliation: Universidade Federal de Sergipe, Aracaju, SE, Brazil.
authors.forename: Marcos Antonio Almeida
authors.initials: MA
authors.lastname: Santos
authors.affiliation: Universidade Federal de Sergipe, Aracaju, SE, Brazil.
authors.forename: Gustavo Baptista de Almeida
authors.initials: GB
authors.lastname: Faro
authors.affiliation: Universidade Federal de Sergipe, Aracaju, SE, Brazil.
authors.forename: Camile Bittencourt
authors.initials: CB
authors.lastname: Soares
authors.forename: Allyson Matos Porto
authors.initials: AM
authors.lastname: Silva
authors.affiliation: Universidade Federal de Sergipe, Aracaju, SE, Brazil.
authors.forename: Paulo Fernando Carvalho
authors.initials: PF
authors.lastname: Secundo
authors.affiliation: Universidade Federal de Sergipe, Aracaju, SE, Brazil.
authors.forename: Clarissa Karine Cardoso
authors.initials: CK
authors.lastname: Teixeira
authors.affiliation: Universidade Federal de Sergipe, Aracaju, SE, Brazil.
authors.forename: Joselina Luzia Menezes
authors.initials: JL
authors.lastname: Oliveira
authors.affiliation: Universidade Federal de Sergipe, Aracaju, SE, Brazil.
authors.forename: Jose Augusto Soares
authors.initials: JA
authors.lastname: Barreto Filho
authors.affiliation: Universidade Federal de Sergipe, Aracaju, SE, Brazil.
authors.forename: Antônio Carlos Sobral
authors.initials: AC
authors.lastname: Sousa
mesh_terms: D054058:Acute Coronary Syndrome / Q000401:mortality / Q000503:physiopathology* / Q000628:therapy; D000368:Aged; D000369:Aged, 80 and over; D016279:Atrial Function, Left / Q000502:physiology*; D002306:Cardiac Volume / Q000502:physiology*; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006325:Heart Atria / Q000503:physiopathology; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D012042:Registries; D018570:Risk Assessment; D012307:Risk Factors; D018709:Statistics, Nonparametric; D013997:Time Factors; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000503:physiopathology