title: Counteracting the inhibitory effect of proteins towards lung surfactant substitutes: a fluorocarbon gas helps displace albumin at the air/water interface.
abstract: Perfluorohexane gas lowers the kinetic barrier that opposes the displacement of albumin by dipalmitoylphosphatidylcholine at the air/water interface submitted to sinusoidal oscillations at frequencies in the range of those encountered in respiration.
authors.affiliation: Systèmes Organisés Fluorés à Finalités Thérapeutiques (SOFFT), Institut Charles Sadron (ICS) CNRS, Université de Strasbourg (UPR 22), 23 rue du Loess, 67034 Strasbourg Cedex 2, France. krafft@unistra.fr.
authors.forename: Phuc Nghia
authors.initials: PN
authors.lastname: Nguyen
authors.forename: Mariam
authors.initials: M
authors.lastname: Veschgini
authors.forename: Motomu
authors.initials: M
authors.lastname: Tanaka
authors.forename: Gilles
authors.initials: G
authors.lastname: Waton
authors.forename: Thierry
authors.initials: T
authors.lastname: Vandamme
authors.forename: Marie Pierre
authors.initials: MP
authors.lastname: Krafft
mesh_terms: D015060:1,2-Dipalmitoylphosphatidylcholine / Q000737:chemistry; D000327:Adsorption; D000388:Air; D000818:Animals; D002417:Cattle; D005466:Fluorocarbons / Q000737:chemistry* / Q000378:metabolism; D005740:Gases / Q000737:chemistry; D007700:Kinetics; D008081:Liposomes / Q000737:chemistry / Q000378:metabolism; D008856:Microscopy, Fluorescence; D011663:Pulmonary Surfactants / Q000737:chemistry* / Q000378:metabolism; D012710:Serum Albumin, Bovine / Q000737:chemistry* / Q000378:metabolism; D014867:Water / Q000737:chemistry
chemical_list: D005466:Fluorocarbons; D005740:Gases; D008081:Liposomes; D011663:Pulmonary Surfactants; D014867:Water; D015060:1,2-Dipalmitoylphosphatidylcholine; D012710:Serum Albumin, Bovine; C078626:perflexane