title: Getting rid of the bad apple: inflammasome-induced extrusion of Salmonella-infected enterocytes.
abstract: Two reports in this issue of Cell Host & Microbe (Sellin et al., 2014; Knodler et al., 2014) establish the cell-intrinsic inflammasome-induced extrusion of infected enterocytes as a general defense mechanism against acute bacterial infections.
authors.affiliation: Focal Area Infection Biology, Biozentrum, University of Basel, 4056 Basel, Switzerland. Electronic address: petr.broz@unibas.ch.
authors.forename: Petr
authors.initials: P
authors.lastname: Broz
mesh_terms: D000818:Animals; D051017:Apoptosis Regulatory Proteins / Q000502:physiology*; D002135:Calcium-Binding Proteins / Q000502:physiology*; D020169:Caspases / Q000378:metabolism*; D053471:Caspases, Initiator / Q000378:metabolism*; D020895:Enterocytes / Q000382:microbiology*; D004927:Escherichia coli Infections / Q000201:enzymology*; D006801:Humans; D058847:Inflammasomes / Q000502:physiology*; D051616:Neuronal Apoptosis-Inhibitory Protein / Q000502:physiology*; D012480:Salmonella Infections / Q000201:enzymology* / Q000276:immunology*; D012486:Salmonella typhimurium / Q000276:immunology*
chemical_list: D051017:Apoptosis Regulatory Proteins; D002135:Calcium-Binding Proteins; D058847:Inflammasomes; C512299:Ipaf protein, mouse; C496801:Naip1 protein, mouse; D051616:Neuronal Apoptosis-Inhibitory Protein; C093516:CASP4 protein, human; C101136:Casp4 protein, mouse; D020169:Caspases; D053471:Caspases, Initiator