title: New cholesterol guidelines and the secondary prevention of cardiovascular disease - a commentary on epistemic aspects.
abstract: The recommendations contained in the 2013 cholesterol guidelines may be described as either with or without a direct empirical clinical trial basis. Recommendations without a direct empirical clinical trial basis tend to be controversial. Recommendations with and without a direct empirical clinical trial basis are mixed in the same text - while at the same time (rightfully) rejecting previous recommendations, also without a direct empirical clinical trial basis.
authors.affiliation: Faculdade de Medicina da Universidade do Porto, Department of Medicine, Alameda Prof. Hernani Monteiro, 4200 Porto, Portugal. Electronic address: jplnunes@med.up.pt.
authors.forename: José Pedro L
authors.initials: JP
authors.lastname: Nunes
mesh_terms: D000368:Aged; D050197:Atherosclerosis / Q000188:drug therapy*; D002318:Cardiovascular Diseases / Q000517:prevention & control; D008078:Cholesterol, LDL / Q000187:drug effects*; D002986:Clinical Trials as Topic; D055317:Evidence-Based Practice; D005260:Female; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000008:administration & dosage* / Q000627:therapeutic use; D006937:Hypercholesterolemia / Q000188:drug therapy / Q000517:prevention & control; D019359:Knowledge; D008297:Male; D008875:Middle Aged; D017410:Practice Guidelines as Topic; D055502:Secondary Prevention / Q000379:methods
chemical_list: D008078:Cholesterol, LDL; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors
keywords: Cholesterol; Guidelines; Statins