title: [Soft tissue tumor near the joint: hibernoma].
abstract: Joint associated tumors must undergo histological analysis, since not only inflammatory, but also benign and malign tumors exist in this location. We report a well circumscribed tumor, located in the elbow that histologically turned out to be a hibernoma. Complete surgical excision is the therapy of choice and recurrences are rare. To rule out liposarcoma with hibernoma like changes, fluorescence in-situ hybridisation has been performed and showed no MDM-2 amplification. Hibernomas are tumors of brown adipose tissue that may be localized next to joints.
authors.affiliation: Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn.
authors.forename: J
authors.initials: J
authors.lastname: Schmolders
authors.affiliation: Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn.
authors.forename: S
authors.initials: S
authors.lastname: Gravius
authors.affiliation: Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn.
authors.forename: M J
authors.initials: MJ
authors.lastname: Friedrich
authors.affiliation: Institut für Pathologie, Universitätsklinikum Heidelberg, Heidelberg.
authors.forename: M
authors.initials: M
authors.lastname: Kriegsmann
authors.affiliation: Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn.
authors.forename: D C
authors.initials: DC
authors.lastname: Wirtz
authors.affiliation: Zentrum für Histologie, Zytologie und Molekulare Diagnostik Trier.
authors.forename: J
authors.initials: J
authors.lastname: Kriegsmann
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D003937:Diagnosis, Differential; D004551:Elbow Joint / Q000473:pathology; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008067:Lipoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D051736:Proto-Oncogene Proteins c-mdm2 / Q000032:analysis; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*
chemical_list: D014408:Biomarkers, Tumor; D051736:Proto-Oncogene Proteins c-mdm2