title: Suicidality in non-treatment seeking young adults with subsyndromal gambling disorder.
abstract: Gambling Disorder is associated with elevated rates of suicidal thoughts and acts. However, virtually nothing is known about suicidality in people with subsyndromal forms of gambling disorder. A total of 174 non-treatment seeking subjects were recruited for a study of impulsivity and met criteria for a subsyndromal form of DSM-5 gambling disorder (31.0 % females; mean age = 21.7 ± 3.61 years). Subjects were categorized as being 'at risk of suicide' or 'no suicide risk' based on the Mini-International Neuropsychiatric Interview (MINI). Those with and without suicidality were compared on clinical and cognitive measures. 32 (18.4 %) met MINI criteria for suicidality. Suicidality was significantly associated with mood and anxiety disorders, greater rates of nicotine consumption, and relative impairments in decision-making and cognitive flexibility. These findings suggest that decision-making impairments may be implicated in the development of both gambling problems and suicidality. Future work should address causality, neural correlates, and tailored suicide prevention strategies for people with, or at risk for, disordered forms of gambling.
authors.affiliation: Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Pritzker School of Medicine, 5841 S. Maryland Avenue, MC 3077, Chicago, IL, 60637, USA, jgrant4@bsd.uchicago.edu.
authors.forename: Jon E
authors.initials: JE
authors.lastname: Grant
authors.forename: Katherine
authors.initials: K
authors.lastname: Derbyshire
authors.forename: Eric
authors.initials: E
authors.lastname: Leppink
authors.forename: Samuel R
authors.initials: SR
authors.lastname: Chamberlain
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology; D005260:Female; D005715:Gambling / Q000150:complications / Q000523:psychology*; D006801:Humans; D008297:Male; D008609:Mental Status Schedule; D013405:Suicide / Q000523:psychology* / Q000706:statistics & numerical data; D055815:Young Adult