title: Nuclear magnetic resonance relaxivities: investigations of ultrahigh-spin lanthanide clusters from 10 MHz to 1.4 GHz.
abstract: Paramagnetic relaxation enhancement is often explored in magnetic resonance imaging in terms of contrast agents and in biomolecular nuclear magnetic resonance (NMR) spectroscopy for structure determination. New ultrahigh-spin clusters are investigated with respect to their NMR relaxation properties. As their molecular size and therefore motional correlation times as well as their electronic properties differ significantly from those of conventional contrast agents, questions about a comprehensive characterization arise. The relaxivity was studied by field-dependent longitudinal and transverse NMR relaxometry of aqueous solutions containing Fe(III)(10)Dy(III)(10) ultrahigh-spin clusters (spin ground state 100/2). The high-field limit was extended to 32.9 T by using a 24 MW resistive magnet and an ultrahigh-frequency NMR setup. Interesting relaxation dispersions were observed; the relaxivities increase up to the highest available fields, which indicates a complex interplay of electronic and molecular correlation times.
authors.affiliation: Pro2NMR at the Institute -for Biological Interfaces, Karlsruhe Institute of Technology, Adenauerring 20b, 76131 Karlsruhe (Germany).
authors.forename: Julyana R
authors.initials: JR
authors.lastname: Machado
authors.forename: Amer
authors.initials: A
authors.lastname: Baniodeh
authors.forename: Annie K
authors.initials: AK
authors.lastname: Powell
authors.forename: Burkhard
authors.initials: B
authors.lastname: Luy
authors.forename: Steffen
authors.initials: S
authors.lastname: Krämer
authors.forename: Gisela
authors.initials: G
authors.lastname: Guthausen
mesh_terms: D005290:Ferric Compounds / Q000737:chemistry; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013113:Spin Labels
chemical_list: D005290:Ferric Compounds; D028581:Lanthanoid Series Elements; D013113:Spin Labels
keywords: Cooperative cluster compounds; NMR spectroscopy; Single molecule magnet; lanthanides; ultrahigh magnetic field