title: The Changes of Muscle FGF-6 Expression at Different Time Points after Exercise-induced Muscle Damage.
abstract: OBJECTIVE
  To investigate the changes of fibroblast growth factor (FGF)-6 expression in the regeneration and repair process after exercise-induced muscle damage (EIMD) and the relationship with skeletal muscle regeneration and repair.
  
  
  METHODS
  The expression of FGF-6 at different time points was examined by reverse transcription-polymerase chain reaction (PCR) and immunohistochemistry staining after a downhill treadmill exercise. Skeletal muscle injury and regeneration at different times after EIMD was assessed by haematoxylin and eosin (H and E) staining.
  
  
  RESULTS
  The FGF-6 protein expression was initially elevated and followed by a gradual reduction, while the changes of FGF-6 mRNA were almost all raised after the treadmill exercise.
  
  
  CONCLUSIONS
  The results point out that FGF-6 is closely related to skeletal muscle regeneration and repair, probably implying a dual function in muscle regeneration.
authors.affiliation: Key Laboratory of Exercise and Health Sciences, Shanghai University of Sport, Ministry of Education, 399 Changhai Road, Shanghai 200438, China. yuxinkaijiang@126.com.
authors.forename: X
authors.initials: X
authors.lastname: Yu
authors.affiliation: Key Laboratory of Exercise and Health Sciences, Shanghai University of Sport, Ministry of Education, 399 Changhai Road, Shanghai 200438, China.
authors.forename: Q
authors.initials: Q
authors.lastname: Zuo
authors.affiliation: Key Laboratory of Exercise and Health Sciences, Shanghai University of Sport, Ministry of Education, 399 Changhai Road, Shanghai 200438, China.
authors.forename: W
authors.initials: W
authors.lastname: Chao
authors.affiliation: Key Laboratory of Exercise and Health Sciences, Shanghai University of Sport, Ministry of Education, 399 Changhai Road, Shanghai 200438, China.
authors.forename: R
authors.initials: R
authors.lastname: Jiang