title: Oral and sublingual immunotherapy.
abstract: Allergic diseases have continued to increase throughout the developed world. Subcutaneous immunotherapy has been a mainstay of treatment for allergic rhinitis and asthma, however, some patients are precluded from treatment. On the other hand, in the case of food allergy, treatments simply do not exist. Oral and sublingual immunotherapy, with its superior safety and ease of administration, offers an alternative for patients with allergic rhinitis and asthma and has also been promising as a potential treatment for food allergy. The review summarizes significant advances from the past year including further data on the effectiveness of existing treatments, preliminary data on novel treatments, and further understanding of the mechanisms of these new therapies.
authors.affiliation: University of North Carolina at Chapel Hill, 2144 Genome Sciences Bldg, CB #7231, Chapel Hill, NC 27599-7231, 919-962-4409 (office), 919-962-4730 (fax).
authors.forename: Edwin H
authors.initials: EH
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, University of North Carolina at Chapel Hill, 260 MacNider Bldg, CB#7220, Chapel Hill, NC 27599-7220, 919-966-1505 (office), 919-966-7299 (fax).
authors.forename: Wesley
authors.initials: W
authors.lastname: Burks
keywords: allergic rhinitis; allergic rhinoconjunctivitis; asthma; food allergy; oral immunotherapy; sublingual immunotherapy