title: Ecocatalysis for 2H-chromenes synthesis: an integrated approach for phytomanagement of polluted ecosystems.
abstract: A direct, general and efficient method to synthesize 2H-chromenes (2H-benzo[b]pyrans), identified as environmentally friendly pesticides, has been developed. This approach lays on the new concept of ecocatalysis, which involves the use of biomass from phytoextraction processes, as a valuable source of metallic elements for chemical synthesis. This methodology is similar or superior to known methods, affording 2H-chromenes with good to excellent yields (60-98%), including the preparation of precocene I, a natural insect growth regulator, with 91% yield. The approach is ideal for poor reactive substrates such as phenol or naphthol, classically transformed into 2H-chromenes by methodologies associated with environmental issues. These results illustrate the interest of combining phytoextraction and green synthesis of natural insecticides.
authors.affiliation: Laboratory of Bio-inspired Chemistry and Ecological Innovations FRE 3673 ChimEco CNRS-UM2, Stratoz, Cap Alpha, Avenue de l'Europe, 34830, Clapiers, France.
authors.forename: Vincent
authors.initials: V
authors.lastname: Escande
authors.forename: Alicia
authors.initials: A
authors.lastname: Velati
authors.forename: Claude
authors.initials: C
authors.lastname: Grison
mesh_terms: D001578:Benzopyrans / Q000737:chemistry / Q000378:metabolism; D001673:Biodegradation, Environmental; D002186:Cannabinoids / Q000138:chemical synthesis / Q000378:metabolism; D002384:Catalysis; D004785:Environmental Pollutants / Q000032:analysis / Q000493:pharmacokinetics*; D055772:Green Chemistry Technology / Q000379:methods*; D007306:Insecticides / Q000138:chemical synthesis*; D058116:Lewis Acids / Q000737:chemistry / Q000378:metabolism; D019684:Magnoliopsida / Q000378:metabolism*; D019216:Metals, Heavy / Q000032:analysis / Q000493:pharmacokinetics*; D015394:Molecular Structure; D010571:Pest Control / Q000379:methods*
chemical_list: C412074:5,7-dimethoxy-2-methyl-2H-benzopyran; D001578:Benzopyrans; D002186:Cannabinoids; D004785:Environmental Pollutants; D007306:Insecticides; D058116:Lewis Acids; D019216:Metals, Heavy; C019539:precocene I