title: Impact of contrast-enhanced ultrasound in the study of hepatic artery hypoperfusion shortly after liver transplantation: contribution to the diagnosis of artery steal syndrome.
abstract: OBJECTIVE
  To assess the value of contrast-enhanced ultrasound (CEUS) in the absence of hepatic artery signal on Doppler ultrasound (DUS) in the immediate postoperative period after liver transplant.
  
  
  METHODS
  This prospective study included 675 consecutive liver transplants. Patients without hepatic artery signal by DUS within 8 days post-transplant were studied with CEUS. If it remained undetectable, a thrombosis was suspected. In patent hepatic artery, a DUS was performed immediately after CEUS; if low resistance flow was detected, an arteriography was indicated. Patients with high resistance waveform underwent DUS+/CEUS follow-up. Arteriography was indicated when abnormal flow persisted for more than 5 days or liver dysfunction appeared.
  
  
  RESULTS
  Thirty-four patients were studied with CEUS. In 11 patients CEUS correctly diagnosed hepatic artery thrombosis. In two out of 23 non-occluded arteries, a low resistance flow lead to a diagnosis of stenosis/proximal thrombosis. Twenty-one patients had absence of diastolic flow, which normalized in the follow-up in 13 patients. In the remaining eight patients, splenic artery steal syndrome (ASS) was diagnosed.
  
  
  CONCLUSIONS
  CEUS allows us to avoid invasive tests in the diagnostic work-up shortly after liver transplant. It identifies the hepatic artery thrombosis and points to a diagnosis of ASS.
  
  
  CONCLUSIONS
  • CEUS is useful in the diagnostic work-up shortly after liver transplant • CEUS identifies the hepatic artery thrombosis with reliability • There is little information about DUS and CEUS findings in the ASS • DUS and CEUS offer functional information useful in the diagnosis of ASS.
authors.affiliation: Department of Radiology, Hospital Clinic of Barcelona, Villarroel 170, 08036, Barcelona, Spain, magarcia@clinic.ub.es.
authors.forename: Angeles
authors.initials: A
authors.lastname: García-Criado
authors.forename: Rosa
authors.initials: R
authors.lastname: Gilabert
authors.forename: Luis
authors.initials: L
authors.lastname: Bianchi
authors.forename: Ramón
authors.initials: R
authors.lastname: Vilana
authors.forename: Marta
authors.initials: M
authors.lastname: Burrel
authors.forename: Marta
authors.initials: M
authors.lastname: Barrufet
authors.forename: Rafael
authors.initials: R
authors.lastname: Oliveira
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: García-Valdecasas
authors.forename: Concepción
authors.initials: C
authors.lastname: Brú
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging* / Q000209:etiology / Q000503:physiopathology; D003287:Contrast Media; D005260:Female; D005500:Follow-Up Studies; D006499:Hepatic Artery / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D008099:Liver / Q000098:blood supply*; D008102:Liver Circulation; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011446:Prospective Studies; D012039:Regional Blood Flow; D015203:Reproducibility of Results; D013577:Syndrome; D018615:Ultrasonography, Doppler, Color / Q000379:methods*; D055815:Young Adult
chemical_list: D003287:Contrast Media