title: In vitro biological activities and fatty acid profiles of Pistacia terebinthus fruits and Pistacia khinjuk seeds.
abstract: This study reports in vitro anticholinesterase, antioxidant and antimicrobial effects of the n-hexane, dichloromethane, ethanol and ethanol-water extracts prepared from Pistacia terebinthus L. fruits and Pistacia khinjuk Stocks seeds as well as their total phenolic and flavonoid contents, and fatty acid compositions. Ethanol and ethanol-water extracts of both species exhibited higher anticholinesterase activity than galanthamine. Among ABTS, DPPH and CUPRAC assays, the highest antioxidant capacity of the extracts was found in the last one. P. terebinthus ethanol extract being rich in flavonoid content showed the best cupric reducing effect. All extracts possessed no antimicrobial activity. The main fatty acid in P. terebinthus fruits (52.52%) and P. khinjuk seeds (59.44%) was found to be oleic acid. Our results indicate that P. terebinthus fruits and P. khinjuk seeds could be a good source of anticholinesterase compounds, and could be phytochemically investigated.
authors.affiliation: a Department of Analytical Chemistry , Faculty of Pharmacy, Bezmialem Vakif University , 34093 Istanbul , Turkey.
authors.forename: Işil
authors.initials: I
authors.lastname: Hacıbekiroğlu
authors.forename: Pelin Köseoğlu
authors.initials: PK
authors.lastname: Yılmaz
authors.forename: Nesrin
authors.initials: N
authors.lastname: Haşimi
authors.forename: Ersin
authors.initials: E
authors.lastname: Kılınç
authors.forename: Veysel
authors.initials: V
authors.lastname: Tolan
authors.forename: Ufuk
authors.initials: U
authors.lastname: Kolak
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry; D000975:Antioxidants / Q000737:chemistry; D002800:Cholinesterase Inhibitors / Q000737:chemistry*; D005227:Fatty Acids / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry; D005638:Fruit / Q000737:chemistry; D019301:Oleic Acid / Q000737:chemistry; D010636:Phenols / Q000737:chemistry; D027927:Pistacia / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry
chemical_list: D000890:Anti-Infective Agents; D000975:Antioxidants; D002800:Cholinesterase Inhibitors; D005227:Fatty Acids; D005419:Flavonoids; D010636:Phenols; D010936:Plant Extracts; D019301:Oleic Acid
keywords: Anacardiaceae; Pistacia khinjuk; Pistacia terebinthus; anticholinesterase; antioxidant; fatty acid