title: Public and patient research priorities for orthostatic hypotension.
abstract: With a rapidly expanding older population and increased survival of older people with chronic disease, we can expect to see increasing numbers of people with orthostatic hypotension (OH). Unfortunately the evidence base for people with OH, with particular relevance to older people, has not kept up and has resulted in a real lack of progress and little good evidence. There are several areas of research that could potentially benefit patients but establishing which ones are priority areas requires public and patient involvement (PPI). This process includes people/patients in the research team to maximise the relevance, success and translation of the research. This brief report describes the early involvement of older people in prioritising the research question, methods to improve adherence during a trial and the preferred methods to disseminate research output. The individuals' priority was to research non-pharmacological treatment strategies and to improve the education of patients about their condition. Education was felt to be the best strategy to promote adherence during a trial, with change in symptoms and quality of life felt to be the most important outcome measures as opposed to blood pressure. This report offers guidance for academics that are undertaking OH-related research and how they can improve its relevance and increase its translation into clinical practice.
authors.affiliation: Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK.
authors.forename: James
authors.initials: J
authors.lastname: Frith
authors.affiliation: The Medical School, Newcastle University, Newcastle upon Tyne, UK.
authors.forename: Ayat S
authors.initials: AS
authors.lastname: Bashir
authors.affiliation: Newcastle University, Newcastle upon Tyne, UK.
authors.forename: Chris S
authors.initials: CS
authors.lastname: Elliott
authors.affiliation: Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK.
authors.forename: Julia L
authors.initials: JL
authors.lastname: Newton
mesh_terms: D000367:Age Factors; D000375:Aging; D003159:Community-Institutional Relations; D032882:Comprehension; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006292:Health Priorities; D006801:Humans; D007024:Hypotension, Orthostatic / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D033181:Information Dissemination; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D010353:Patient Education as Topic; D010358:Patient Participation; D057240:Patient Preference; D011639:Public Opinion; D057170:Translational Research, Biomedical
keywords: older people; orthostatic hypotension; patient adherence; patient education