title: Developing a genetic fuzzy system for risk assessment of mortality after cardiac surgery.
abstract: Cardiac events could be taken into account as the leading causes of death throughout the globe. Such events also trigger an undesirable increase in what treatment procedures cost. Despite the giant leaps in technological development in heart surgery, coronary surgery still carries the high risk of the mortality. Besides, there is still a long way ahead to accurately predict and assess the mortality risk. This study is an attempt to develop an expert system for the risk assessment of mortality following the cardiac surgery. The developed system involves three main steps. In the first step, a filtering feature selection method is applied to select the best features. In the second step, an ad hoc data-driven method is utilized to generate the preliminary fuzzy inference system. Finally, a hybrid optimization method is presented to select the optimum subset of the rules. The study relies on 1,811 samples to evaluate the diagnosis performance of the proposed system. The obtained classification accuracy is very promising with regard to other benchmark classification methods including binary logistic regression (LR) and multilayer perceptron neural network (MLP) with the same attributes. The developed system leads to 100% sensitivity and 84.7% specificity, while LR and MLP methods statistically come up with lower figures (65, 78.6 and 65%, 75.8%), respectively. Now, a fuzzy supportive tool can be potentially taken as an alternative for the current mortality risk assessment system that are applied in coronary surgeries, and are chiefly based on crisp database.
authors.affiliation: Department of Applied Mathematics, School of Mathematical Sciences, Ferdowsi University of Mashhad, International Campus, Mashhad, Iran, M.nouei@yahoo.ca.
authors.forename: Mahyar Taghizadeh
authors.initials: MT
authors.lastname: Nouei
authors.forename: Ali Vahidian
authors.initials: AV
authors.lastname: Kamyad
authors.forename: MahmoodReza
authors.initials: M
authors.lastname: Sarzaeem
authors.forename: Somayeh
authors.initials: S
authors.lastname: Ghazalbash
mesh_terms: D000368:Aged; D000465:Algorithms; D003324:Coronary Artery Disease / Q000401:mortality / Q000601:surgery*; D005103:Expert Systems; D017143:Fuzzy Logic; D006801:Humans; D008875:Middle Aged; D018570:Risk Assessment / Q000379:methods*; D012680:Sensitivity and Specificity; D019616:Thoracic Surgical Procedures / Q000401:mortality*