title: Comparison of Korean COPD guideline and GOLD initiative report in term of acute exacerbation: a validation study for Korean COPD guideline.
abstract: The purpose of this study was to compare the Korean COPD guideline to GOLD consensus report in terms of acute exacerbation. A total of 361 patients were enrolled in this study, and 16.9% of them experienced acute exacerbation during the follow-up. A total of 6.3% of patients in GOLD A, 9.5% in GOLD B, 7.7% in GOLD C and 17.0% of GOLD D experienced exacerbation during the first year of follow-up, respectively (P=0.09). There was no one who experienced exacerbation during the first year of follow-up in the Korean group 'ga'. The 12-month exacerbation rates of Korean group 'na' and 'da' were 4.5% and 16.0%, respectively (P<0.001). We explore the experience of exacerbation in patients with change of their risk group after applying Korean COPD guideline. A total of 16.0% of the patients who were reclassified from GOLD A to Korean group 'da' experienced acute exacerbation,and 15.3% from GOLD B to Korean group 'da' experienced acute exacerbation. In summary, the Korean COPD guideline is useful to differentiate the high risk from low risk for exacerbation in terms of spirometry. This indicates that application of Korean COPD guideline is appropriate to treat Korean COPD patients.
authors.affiliation: Department of Pulmonary, Allergy and Critical Care Medicine, Hallym University Medical Center, Hallym University College of Medicine, Anyang, Korea.
authors.forename: Yong Il
authors.identifier: 0000-0002-3502-5211
authors.initials: YI
authors.lastname: Hwang
authors.affiliation: Department of Pulmonary, Allergy and Critical Care Medicine, Hallym University Medical Center, Hallym University College of Medicine, Anyang, Korea.
authors.forename: Yong Bum
authors.identifier: 0000-0001-8810-6077
authors.initials: YB
authors.lastname: Park
authors.affiliation: Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Yeon Mok
authors.identifier: 0000-0003-0116-4683
authors.initials: YM
authors.lastname: Oh
authors.affiliation: Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
authors.forename: Ji Hyun
authors.identifier: 0000-0002-8287-5470
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.
authors.forename: Tae Hyung
authors.identifier: 0000-0002-3863-7854
authors.initials: TH
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Konkuk University College of Medicine, Seoul, Korea.
authors.forename: Kwang Ha
authors.identifier: 0000-0001-9969-2657
authors.initials: KH
authors.lastname: Yoo
authors.affiliation: Department of Internal Medicine, Yeouido St. Marry's Hosital, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors.forename: Hyoung Kyu
authors.initials: HK
authors.lastname: Yoon
authors.affiliation: Department of Internal Medicine, St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors.forename: Chin Kook
authors.identifier: 0000-0003-4533-7937
authors.initials: CK
authors.lastname: Rhee
authors.affiliation: Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.
authors.forename: Deog Kyeom
authors.identifier: 0000-0001-9379-8098
authors.initials: DK
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine,Yeungnam University College of Medicine, Daegu, Korea.
authors.forename: Kyeong Cheol
authors.initials: KC
authors.lastname: Shin
authors.affiliation: Department of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea.
authors.forename: Sang Yeub
authors.identifier: 0000-0001-7565-1076
authors.initials: SY
authors.lastname: Lee
authors.affiliation: Department of Pulmonary, Allergy and Critical Care Medicine, Hallym University Medical Center, Hallym University College of Medicine, Anyang, Korea.
authors.forename: Ki-Suck
authors.identifier: 0000-0002-6878-6543
authors.initials: KS
authors.lastname: Jung
mesh_terms: D000208:Acute Disease; D000368:Aged; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D017410:Practice Guidelines as Topic; D029424:Pulmonary Disease, Chronic Obstructive / Q000145:classification* / Q000175:diagnosis*; D015272:Pulmonary Medicine / Q000592:standards*; D015203:Reproducibility of Results; D056910:Republic of Korea; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D013147:Spirometry / Q000592:standards*
keywords: Assessment; COPD; Exacerbation; FEV1; Guidelines