title: Progenitor genealogy in the developing cerebral cortex.
abstract: The mammalian cerebral cortex is characterized by a complex histological organization that reflects the spatio-temporal stratifications of related stem and neural progenitor cells, which are responsible for the generation of distinct glial and neuronal subtypes during development. Some work has been done to shed light on the existing filiations between these progenitors as well as their respective contribution to cortical neurogenesis. The aim of the present review is to summarize the current views of progenitor hierarchy and relationship in the developing cortex and to further discuss future research directions that would help us to understand the molecular and cellular regulating mechanisms involved in cerebral corticogenesis.
authors.affiliation: GIGA-Neurosciences, University of Liège, C.H.U. Sart Tilman, Liège, 4000, Belgium.
authors.forename: Sophie
authors.initials: S
authors.lastname: Laguesse
authors.forename: Elise
authors.initials: E
authors.lastname: Peyre
authors.forename: Laurent
authors.initials: L
authors.lastname: Nguyen
mesh_terms: D000818:Animals; D005075:Biological Evolution; D019070:Cell Lineage; D002540:Cerebral Cortex / Q000166:cytology* / Q000196:embryology*; D006801:Humans; D058953:Neural Stem Cells / Q000166:cytology*; D009474:Neurons / Q000166:cytology; D008941:Spindle Apparatus / Q000378:metabolism