title: Targeted theranostic prodrugs based on an aggregation-induced emission (AIE) luminogen for real-time dual-drug tracking.
abstract: A targeted theranostic delivery system containing two prodrugs with drug tracking and activation monitoring functions was developed for visualizing cancer cell ablation with synergistic anticancer effects.
authors.affiliation: Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore117576. cheliub@nus.edu.sg.
authors.forename: Youyong
authors.initials: Y
authors.lastname: Yuan
authors.forename: Ryan T K
authors.initials: RT
authors.lastname: Kwok
authors.forename: Ruoyu
authors.initials: R
authors.lastname: Zhang
authors.forename: Ben Zhong
authors.initials: BZ
authors.lastname: Tang
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry* / Q000633:toxicity; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D002945:Cisplatin / Q000737:chemistry / Q000633:toxicity; D004317:Doxorubicin / Q000737:chemistry / Q000633:toxicity; D004337:Drug Carriers / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D057809:HEK293 Cells; D006801:Humans; D018613:Microscopy, Confocal; D010456:Peptides, Cyclic / Q000737:chemistry; D011355:Prodrugs / Q000737:chemistry* / Q000633:toxicity
chemical_list: D000970:Antineoplastic Agents; D004337:Drug Carriers; D005456:Fluorescent Dyes; D010456:Peptides, Cyclic; D011355:Prodrugs; C507169:cyclic arginine-glycine-aspartic acid peptide; D004317:Doxorubicin; D002945:Cisplatin