title: Catalyst design in oxidation chemistry; from KMnO4 to artificial metalloenzymes.
abstract: Oxidation reactions are an important part of the synthetic organic chemist's toolkit and continued advancements have, in many cases, resulted in high yields and selectivities. This review aims to give an overview of the current state-of-the-art in oxygenation reactions using both chemical and enzymatic processes, the design principles applied to date and a possible future in the direction of hybrid catalysts combining the best of chemical and natural design.
authors.affiliation: School of Chemistry, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, United Kingdom.
authors.forename: Megan V
authors.initials: MV
authors.lastname: Doble
authors.affiliation: School of Chemistry, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, United Kingdom.
authors.forename: Andrew C C
authors.initials: AC
authors.lastname: Ward
authors.affiliation: Stratingh Institute for Chemistry, Rijksuniversiteit Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Deuss
authors.affiliation: School of Chemistry, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, United Kingdom. Electronic address: agj2@st-andrews.ac.uk.
authors.forename: Amanda G
authors.initials: AG
authors.lastname: Jarvis
authors.affiliation: School of Chemistry, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, United Kingdom.
authors.forename: Paul C J
authors.initials: PC
authors.lastname: Kamer
mesh_terms: D002384:Catalysis; D008667:Metalloproteins / Q000737:chemistry* / Q000378:metabolism; D008958:Models, Molecular; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011196:Potassium Permanganate / Q000737:chemistry*
chemical_list: D008667:Metalloproteins; D011196:Potassium Permanganate
keywords: Artificial enzymes; Biocatalysis; Homogenous catalysis; N-ligands; Oxidation