title: Impact of dairy consumption on essential hypertension: a clinical study.
abstract: BACKGROUND
  Several studies have presented evidence suggesting that dairy consumption has beneficial effects on blood pressure (BP) in healthy subjects; however, only a few studies have examined this possibility in patients with established essential hypertension using ambulatory blood pressure monitoring. The objective of this study was to investigate how consuming dairy products impacts mean daytime systolic and diastolic BP in men and women with mild to moderate essential hypertension.
  
  
  METHODS
  Eighty-nine men and women with systolic BP ≥ 135 mm Hg and ≤ 160 mm Hg and diastolic BP ≤ 110 mm Hg were enrolled in this single-blind, randomized, cross-over, controlled study. Participants had to incorporate three daily servings of dairy products or control products equivalent in macronutrients and sodium during four-week treatment phases. Twenty-four hour ambulatory BP and endothelial function were assessed at screening and at the end of each dietary phase.
  
  
  RESULTS
  The consumption of three daily servings of dairy products led to a significant reduction in mean daytime ambulatory systolic BP (-2 mm Hg; P = 0.05) in men compared with readings after the control phase. In women, dairy consumption had no effect on ambulatory systolic BP. Moreover, endothelial function was significantly improved by dairy consumption in the whole cohort.
  
  
  CONCLUSIONS
  These data indicate that the consumption of three daily servings of dairy products have beneficial effects on daytime systolic ambulatory BP compared to a heart-healthy, dairy-free, diet in men with mild to moderate essential hypertension.
  
  
  BACKGROUND
  This trial is registered at clinicaltrials.gov as NCT01776216.
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Drouin-Chartier
authors.forename: Iris
authors.initials: I
authors.lastname: Gigleux
authors.forename: André J
authors.initials: AJ
authors.lastname: Tremblay
authors.forename: Luc
authors.initials: L
authors.lastname: Poirier
authors.forename: Benoît
authors.initials: B
authors.lastname: Lamarche
authors.affiliation: Institute of Nutrition and Functional Foods (INAF), Pavillon des Services, Laval University, 2440, Hochelaga Blvd, Quebec City G1V 0A6, Canada. patrick.couture@crchul.ulaval.ca.
authors.forename: Patrick
authors.initials: P
authors.lastname: Couture
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000502:physiology; D018660:Blood Pressure Monitoring, Ambulatory / Q000379:methods; D018592:Cross-Over Studies; D003611:Dairy Products; D004032:Diet; D000075222:Essential Hypertension; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D006973:Hypertension / Q000178:diet therapy*; D008297:Male; D008875:Middle Aged; D016037:Single-Blind Method; D012982:Sodium, Dietary / Q000008:administration & dosage; D055815:Young Adult
chemical_list: D012982:Sodium, Dietary