title: Febrile seizures: etiology, prevalence, and geographical variation.
abstract: OBJECTIVE
  Febrile seizures (FSs) are the most common neurological disorder observed in the pediatric age group. The present study provides information about epidemiological and clinical characteristics as well as risk factors associated with FS among Iranian children.
  
  
  METHODS
  On the computerized literature valid databases, the FS prevalence and 95% confidence intervals were calculated using a random effects model. A metaregression analysis was introduced to explore heterogeneity between studies. Data manipulation and statistical analyses were performed using Stata10.
  
  
  RESULTS
  The important viral or bacterial infection causes of FSs were; recent upper respiratory infection 42.3% (95% CI: 37.2%-47.4%), gastroenteritis21.5% (95% CI: 13.6%-29.4%), and otitis media nfections15.2% (95% CI: 9.8%- 20.7%) respectively. The pooled prevalence rate of FS among other childhood convulsions was 47.9% (95% CI: 38.8-59.9%). The meta-regression analysis showed that the sample size does not significantly affect heterogeneity for the factor 'prevalence FS'.
  
  
  CONCLUSIONS
  Almost half of all childhood convulsions among Iranian children are associated with Febrile seizure.
authors.affiliation: Prevention of Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam, Iran ; Department of Clinical Epidemiology, Ilam University of Medical Sciences, Ilam, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Delpisheh
authors.affiliation: Department of Clinical Epidemiology, Ilam University of Medical Sciences, Ilam, Iran ; The Student Research Committee, Ilam University of Medical Sciences, Ilam, Iran.
authors.forename: Yousef
authors.initials: Y
authors.lastname: Veisani
authors.affiliation: Prevention of Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam, Iran ; Department of Community Medicine, Ilam University of Medical Sciences, Ilam, Iran.
authors.forename: Kourosh
authors.initials: K
authors.lastname: Sayehmiri
authors.affiliation: Department of Pediatric, Neurology, Hamaden University of Medical Sciences, Hamadan, Iran.
authors.forename: Afshin
authors.initials: A
authors.lastname: Fayyazi
keywords: Febrile seizure; Iran; Meta–analysis; Pediatrics