title: [Clinical aspects of the problem of vertebral metastases, possibilities of modern treatment methods, considering especially radiofrequency ablation].
abstract: From 100,000 people in Germany, statistically calculated, 441 males and 350 females suffer from a cancer disease. In about 50 to 80 % of patients with breast or prostate carcinoma bone metastases are registered, which is connected, among others, with a high risk for pathological fractures and other debilitating diseases. The diagnosis of bone metastases is done by conventional X-ray equipment, CT, MRI, and especially with the help of skeletal scintigraphy. For therapy bisphosphonates, anti-hormones and chemotherapeutic agents as drugs are used. Furthermore, radiotherapy, radionuclides, surgery and ablative procedures are applied. A more recent technical method is the STAR™ Tumour Ablation System (RFA), by which minimally invasively an electrode is introduced into the vertebral bodies. The system ensures precise control and thus a targeted ablation of the metastases. Several publications and reports describing a combined application demonstrate the synergistic effectiveness of RFA and radiofrequency kyphoplasty.
authors.affiliation: Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn.
authors.forename: R
authors.initials: R
authors.lastname: Bornemann
authors.affiliation: Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn.
authors.forename: T R
authors.initials: TR
authors.lastname: Jansen
authors.affiliation: Reimbursement and Funding Consultancy for Medical Devices, MedImbursement, Tarmstedt.
authors.forename: M
authors.initials: M
authors.lastname: Wollny
authors.affiliation: Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn.
authors.forename: D C
authors.initials: DC
authors.lastname: Wirtz
authors.affiliation: Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn.
authors.forename: R
authors.initials: R
authors.lastname: Pflugmacher
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D017115:Catheter Ablation; D003430:Cross-Sectional Studies; D003952:Diagnostic Imaging; D005260:Female; D005598:Fractures, Spontaneous / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D006801:Humans; D058498:Kyphoplasty / Q000379:methods; D008297:Male; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D016103:Spinal Fractures / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D013125:Spinal Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000556:secondary* / Q000601:surgery*