title: Regioselective formal hydroamination of styrenes with 1-phenyl-1H-tetrazole-5-thiol.
abstract: 1-Phenyl-1H-tetrazole-5-thiol 1 (PT-thiol) is employed in a unique Markovnikov-selective formal hydroamination of styrenyl compounds in the presence of catalytic amounts of Ga(OTf)3. This gives rise to the formation of tetrazolothione moieties in an atom-economical manner. Mechanistically, we have determined that this transformation may occur by kinetically favored hydrothiolation, followed by rearrangement to the observed hydroamination products.
authors.affiliation: Department of Chemistry, Dartmouth College , Hanover, New Hampshire 03755, United States.
authors.forename: Markku A
authors.initials: MA
authors.lastname: Savolainen
authors.forename: Xinping
authors.initials: X
authors.lastname: Han
authors.forename: Jimmy
authors.initials: J
authors.lastname: Wu