title: Primary renal angiosarcoma with extensive necrosis: a difficult diagnosis.
abstract: Angiosarcoma of the kidney is an exceedingly rare and aggressive neoplasm. Very few cases have been reported in the English literature to date. We report a case of primary renal angiosarcoma with extensive necrosis and discuss its diagnostic difficulties. An 86-year-old male presented with a 12 cm necrotic renal mass and multiple pulmonary and hepatic nodules. A CT guided renal biopsy revealed extensive necrosis and few vascular channels lined by malignant endothelial cells. Diagnosis was given on a morphologic base and proven by an immunohistochemical study. Primary renal angiosarcoma should be included among the differential diagnosis of necrotic renal lesions.
authors.affiliation: Department of Pathology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
authors.forename: Sohail
authors.identifier: 0000-0001-9944-0679
authors.initials: S
authors.lastname: Qayyum
authors.affiliation: Department of Pathology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
authors.forename: Jignesh G
authors.initials: JG
authors.lastname: Parikh
authors.affiliation: Department of Pathology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
authors.forename: Nadeem
authors.identifier: 0000-0003-2106-7063
authors.initials: N
authors.lastname: Zafar