title: Retracted: Association of aldosterone synthase (CYP11B2) gene polymorphism with IgA nephropathy risk and progression of IgA nephropathy.
abstract: OBJECTIVE
  This meta-analysis was conducted to assess the association of aldosterone synthase (CYP11B2) gene polymorphism with the risk of immunoglobulin A (IgA) nephropathy (IgAN) and the progression of IgAN.
  
  
  METHODS
  The literature on associations was identified from PubMed and the Cochrane Library on 1 October 2013, and eligible reports were synthesized.
  
  
  RESULTS
  Eligible reports were recruited into this meta-analysis for the association of CYP11B2-344C/T (rs1799998) gene polymorphism with IgAN risk, and the progression of IgAN. In this meta-analysis, the association of CYP11B2-344C/T (rs1799998) gene polymorphism with IgAN risk was not found in overall populations and in Asians. Interestingly, the C allele and CC genotype were associated with the risk of IgAN in Caucasians, but the TT genotype was not.
  
  
  CONCLUSIONS
  CYP11B2-344C/T gene polymorphism is not associated with IgAN risk and IgAN progression in overall populations and in Asians, but CYP11B2 C allele and CC genotype were associated with the risk of IgAN in Caucasians. However, more studies should be performed in the future to confirm this association.
authors.affiliation: Department of Nephrology, Central Hospital of Huizhou, China.
authors.forename: Weiqiang
authors.initials: W
authors.lastname: Zhong
authors.affiliation: Department of Nephrology, Central Hospital of Huizhou, China.
authors.forename: Zhongliang
authors.initials: Z
authors.lastname: Huang
authors.affiliation: Department of Nephrology, Central Hospital of Huizhou, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Wu
authors.affiliation: Department of Nephrology, Sixth Affiliated Hospital of Sun Yat-Sen University, China zongpeijiang@yeah.net.
authors.forename: Zongpei
authors.initials: Z
authors.lastname: Jiang
authors.affiliation: Department of Nephrology, Sixth Affiliated Hospital of Sun Yat-Sen University, China.
authors.forename: Tian-Biao
authors.initials: TB
authors.lastname: Zhou
keywords: CYP11B2; IgA nephropathy; aldosterone synthase; gene polymorphism; meta-analysis