title: [Diaphragmatic bronchogenic cyst: an exceptional location].
abstract: A 64-year-old man complained of persistent dyspnea and bilateral basi-thoracic pain with shoulder irradiation. Chest computed tomography revealed a heterogeneous left diaphragmatic mass, while magnetic resonance imaging showed hypo-T1 and hyper-T2 signal. Positron-emission tomography did not show any hypermetabolism. Video-assisted thoracic surgery was decided. At inspection, tumour appeared within the posterior costal part of the diaphragmatic muscle. Tumour resection was extended to a 8-cm-long portion of the lumbar part of diaphragm. Diaphragm was repaired with non-absorbable interrupted sutures. Postoperative course was uneventful. Final pathology revealed an intra-diaphragmatic bronchogenic cyst, which is an exceptional condition. Primary diaphragmatic tumours are very rare and preoperative diagnosis cannot be affirmed. Embryologic hypotheses (migration along the oesophagus or envelopment within diaphragmatic precursors of an abnormal supernumerary lung bud) including recent molecular findings of deregulated pathways (fibroblast growth factor-10 and NOTCH) are discussed.
authors.affiliation: Département chirurgie thoracique et transplantation pulmonaire, université Paris-Descartes, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Legras
authors.affiliation: Département chirurgie thoracique et transplantation pulmonaire, université Paris-Descartes, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris, France.
authors.forename: P
authors.initials: P
authors.lastname: Mordant
authors.affiliation: Service de cytologie et d'anatomie pathologique, université Paris-Descartes, hôpital européen Georges-Pompidou, 75015 Paris, France.
authors.forename: L
authors.initials: L
authors.lastname: Gibault
authors.affiliation: Service de radiologie, université Paris-Descartes, hôpital européen Georges-Pompidou, 75015 Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Hernigou
authors.affiliation: Département chirurgie thoracique et transplantation pulmonaire, université Paris-Descartes, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Le Pimpec Barthes
authors.affiliation: Département chirurgie thoracique et transplantation pulmonaire, université Paris-Descartes, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris, France. Electronic address: marc.riquet@egp.aphp.fr.
authors.forename: M
authors.initials: M
authors.lastname: Riquet
mesh_terms: D001994:Bronchogenic Cyst / Q000175:diagnosis* / Q000601:surgery; D003964:Diaphragm / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D020775:Thoracic Surgery, Video-Assisted / Q000379:methods*; D014057:Tomography, X-Ray Computed
keywords: (Diaphragm); Diaphragme; Embryologie; Embryology; Lung (benign or congenital lesions); Lésion bénigne ou congénitale; Poumon; Tumeur; Tumour