title: Multiciliogenesis: multicilin directs transcriptional activation of centriole formation.
abstract: During differentiation of multiciliated cells, numerous centrioles are generated in each cell to act as templates for the formation of a corresponding number of cilia. A new study reveals that multicilin, a protein required for multiciliogenesis, is a key component of a regulatory complex that activates the transcription of genes required for centriole formation.
authors.affiliation: Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland.
authors.forename: Fernando R
authors.initials: FR
authors.lastname: Balestra
authors.affiliation: Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland. Electronic address: pierre.gonczy@epfl.ch.
authors.forename: Pierre
authors.initials: P
authors.lastname: Gönczy
mesh_terms: D000818:Animals; D002502:Centrioles / Q000378:metabolism*; D050684:E2F Transcription Factors / Q000378:metabolism*; D029867:Xenopus Proteins / Q000378:metabolism*
chemical_list: D050684:E2F Transcription Factors; D029867:Xenopus Proteins