title: Retinal detachment associated with ocular toxoplasmosis.
abstract: OBJECTIVE
  To assess the frequency of retinal detachment (RD) and associated clinical features in ocular toxoplasmosis.
  
  
  METHODS
  A review of the medical records of patients diagnosed with ocular toxoplasmosis and follow-up of 6 months or more was conducted. All patients were seen at the Casey Eye Institute at the Oregon Health & Science University over a 9-year period (2003-2012). Demographic data, presence of RD and/or vitritis, and treatments were reviewed. Main outcome measures were the rate of RD in ocular toxoplasmosis, degree of vision loss, and final anatomical status of the retina. Disease- and treatment-related factors associated with poor visual outcome were also analyzed.
  
  
  RESULTS
  Thirty-five eyes of 28 patients with ocular toxoplasmosis and sufficient follow-up were studied. Median age of patients was 40 years (range, 7-93 years). Median follow-up time was 22.5 months (range, 6-96 months). Four of thirty-five eyes (11.4%) developed RD with a frequency of 0.06 RD events per patient-year of follow-up in this sample in a single center. Of four patients with RD, three underwent pars plana vitrectomy and one underwent laser retinopexy. Two of the 4 patients had recurrent RD requiring scleral buckle. At final follow-up, all patients who underwent surgical repair had attached retinas; however, 3 of 4 patients had severe vision loss (20/200 or worse).
  
  
  CONCLUSIONS
  Retinal detachment occurred in 11% of eyes in this study that led to severe vision loss despite successful RD repair.
authors.affiliation: *Department of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, Portland, Oregon; †Department of Ophthalmology, Emory Eye Center, Emory University, Atlanta, Georgia; ‡Portland Veterans Association Medical Center, Portland, Oregon; and §Department of Ophthalmology, Flinders University, Adelaide, Australia.
authors.forename: Ambar
authors.initials: A
authors.lastname: Faridi
authors.forename: Steven
authors.initials: S
authors.lastname: Yeh
authors.forename: Eric B
authors.initials: EB
authors.lastname: Suhler
authors.forename: Justine R
authors.initials: JR
authors.lastname: Smith
authors.forename: Christina J
authors.initials: CJ
authors.lastname: Flaxel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D002648:Child; D058450:Endotamponade; D015822:Eye Infections, Parasitic / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology*; D005260:Female; D006801:Humans; D017075:Laser Coagulation; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment / Q000175:diagnosis / Q000469:parasitology* / Q000601:surgery; D012307:Risk Factors; D012591:Scleral Buckling; D014126:Toxoplasmosis, Ocular / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology*; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy
chemical_list: D000981:Antiprotozoal Agents