title: Rapid time to results and high sensitivity of the CarbaNP test on early cultures.
abstract: For rapid results, we adapted the CarbaNP test by using 5-hour-old cultures; the sensitivity and specificity for detection of carbapenemase production were 100% for non-OXA-producing organisms. The sensitivity from early cultures was 94% for detection of carbapenemase production in Enterobacteriaceae strains. Utilizing younger cultures allows the test to be incorporated into a single day's workflow, facilitating timely patient care and antimicrobial stewardship.
authors.affiliation: Monash Infectious Diseases and Microbiology, Monash Health, Clayton, Victoria, Australia.
authors.forename: Lai-yang
authors.initials: LY
authors.lastname: Lee
authors.affiliation: Monash Infectious Diseases and Microbiology, Monash Health, Clayton, Victoria, Australia Department of Medicine, Monash University, Clayton, Victoria, Australia.
authors.forename: Tony M
authors.initials: TM
authors.lastname: Korman
authors.affiliation: Monash Infectious Diseases and Microbiology, Monash Health, Clayton, Victoria, Australia maryza.graham@monashhealth.org.
authors.forename: Maryza
authors.initials: M
authors.lastname: Graham
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001426:Bacterial Proteins / Q000032:analysis*; D004755:Enterobacteriaceae / Q000201:enzymology* / Q000254:growth & development / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D012680:Sensitivity and Specificity; D013997:Time Factors; D001618:beta-Lactamases / Q000032:analysis*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D001618:beta-Lactamases; C063912:carbapenemase