title: [Stem cell-based therapy in orthopaedics and trauma surgery - current concepts].
abstract: Over the last few years, numerous new treatment methods have been developed for musculoskeletal diseases. Some of these new methods are based on the targeted use of stem cells to initiate healing processes, to compensate for deficits or to activate the regeneration of tendons, muscles, bones and cartilage. This goal can be achieved through the direct use of stem cells on or in a carrier material or through a combination with tissue engineering. In this article, we give a short overview of the possible fields of application of inducible pluripotent haematopoietic, and adult stem cells as well as on their use in musculoskeletal tissue. Furthermore, we provide a summary of the current legal situation concerning the application of stem cells in humans.
authors.affiliation: Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn.
authors.forename: T M
authors.initials: TM
authors.lastname: Randau
authors.affiliation: Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn.
authors.forename: S
authors.initials: S
authors.lastname: Gravius
authors.affiliation: Siegfried Weller Institut für Unfallmedizinische Forschung, BG Unfallklinik, Eberhard-Karls Universität Tübingen.
authors.forename: A
authors.initials: A
authors.lastname: Nüssler
mesh_terms: D006801:Humans; D045164:Mesenchymal Stem Cell Transplantation; D009140:Musculoskeletal Diseases / Q000628:therapy*; D039904:Pluripotent Stem Cells / Q000637:transplantation; D033581:Stem Cell Transplantation / Q000331:legislation & jurisprudence; D023822:Tissue Engineering / Q000331:legislation & jurisprudence