title: Multicystic dysplastic kidney: a retrospective study.
abstract: OBJECTIVE
  To report the renal structural and functional anomalies in children with multicystic dysplastic kidneys.
  
  
  METHODS
  Retrospective descriptive analysis of 47 children with multicystic dysplastic kidney seen in a pediatric nephrology unit over a period of 6 years.
  
  
  RESULTS
  Antenatal diagnosis of multicystic dysplastic kidney was made in 34 (72.3%) patients. On follow up of 31 children for more than 12 months, 21 (68%) had involution, 4 [13%] had non-regression, and 4 (13%) were nephrectomized. Vesico-ureteric reflux (n=13; 28%) was the commonest renal abnormality. The serum creatinine values were higher (P=0.006) in children with contralateral reflux. Sub-nephrotic proteinuria was noted in 9 (29%) and was significantly associated with complete involution (P=<0.023). None of the patients developed hypertension and 2 (6.4%) had renal failure.
  
  
  CONCLUSIONS
  Close nephrological follow-up is needed in children with multicystic dysplasia of kidneys.
authors.affiliation: Departments of *Pediatrics and Pediatric Nephrology, Mehta Children's Hospital, Chetpet, Chennai, India. Correspondence to: Dr M Vijayakumar, Consultant Pediatric Nephrologist, Mehta Children's Hospital, No.2(e) Mc Nichols Road, 3rd Lane, Chetpet, Chennai 600 031, Tamilnadu, India. doctormvk@gmail.com.
authors.forename: Sathish
authors.initials: S
authors.lastname: Sharada
authors.forename: Mahalingam
authors.initials: M
authors.lastname: Vijayakumar
authors.forename: Prahlad
authors.initials: P
authors.lastname: Nageswaran
authors.forename: Sudha
authors.initials: S
authors.lastname: Ekambaram
authors.forename: Amish
authors.initials: A
authors.lastname: Udani
mesh_terms: D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D007668:Kidney / Q000503:physiopathology; D008297:Male; D021782:Multicystic Dysplastic Kidney / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D011507:Proteinuria; D012189:Retrospective Studies; D014718:Vesico-Ureteral Reflux