title: Associations between liver enzymes, psychopathological and clinical features in eating disorders.
abstract: Elevated aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels are frequently reported in patients with anorexia nervosa (AN) and in subjects who are overweight or with hyperlipidemia, which can be found to be associated with binge eating disorder (BED) and bulimia nervosa (BN). Liver functioning and psychopathological features have been evaluated in 43 patients with AN, 33 with BN, and 32 with BED. Body mass index was found to be inversely associated with AST and ALT in AN, and directly associated with AST and ALT in BED. A positive association between ALT and AST and body shape concern in AN was observed. Liver enzymes could be considered as an index of severity in AN and BED patients.
authors.affiliation: Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Firenze, Italy.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Lelli
authors.forename: Giovanni
authors.initials: G
authors.lastname: Castellini
authors.forename: Tommaso
authors.initials: T
authors.lastname: Gabbani
authors.forename: Lucia
authors.initials: L
authors.lastname: Godini
authors.forename: Francesco
authors.initials: F
authors.lastname: Rotella
authors.forename: Valdo
authors.initials: V
authors.lastname: Ricca
mesh_terms: D000293:Adolescent; D000328:Adult; D000410:Alanine Transaminase / Q000097:blood*; D001219:Aspartate Aminotransferases / Q000097:blood*; D015992:Body Mass Index; D001068:Feeding and Eating Disorders / Q000097:blood / Q000175:diagnosis / Q000201:enzymology*; D005260:Female; D006801:Humans; D008099:Liver / Q000201:enzymology*; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D050177:Overweight; D011599:Psychopathology; D055815:Young Adult
chemical_list: D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
keywords: ALT; AST; BMI; eating disorders; psychopathology