title: Side effects of yttrium-90 radioembolization.
abstract: Limited therapeutic options are available for hepatic malignancies. Image guided targeted therapies have established their role in management of primary and secondary hepatic malignancies. Radioembolization with yttrium-90 ((90)Y) microspheres is safe and efficacious for treatment of hepatic malignancies. The tumoricidal effect of radioembolization is predominantly due to radioactivity and not ischemia. This article will present a comprehensive review of the side effects that have been associated with radioembolization using (90)Y microspheres. Some of the described side effects are associated with all transarterial procedures. Side effects specific to radioembolization will also be discussed in detail. Methods to decrease the incidence of these potential side effects will also be discussed.
authors.affiliation: Section of Interventional Radiology, Department of Radiology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University , Chicago, IL , USA.
authors.forename: Ahsun
authors.initials: A
authors.lastname: Riaz
authors.affiliation: Section of Interventional Radiology, Department of Radiology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University , Chicago, IL , USA.
authors.forename: Rafia
authors.initials: R
authors.lastname: Awais
authors.affiliation: Section of Interventional Radiology, Department of Radiology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University , Chicago, IL , USA.
authors.forename: Riad
authors.initials: R
authors.lastname: Salem
keywords: complications of cancer therapy; liver neoplasms; radiation effects; radioembolization; side effects