title: A highly enantioselective hydrogenation of silyl enol ethers catalyzed by chiral frustrated Lewis pairs.
abstract: Using a simple combination of tri-tert-butylphosphine and chiral borane generated in situ by the hydroboration of chiral diene with HB(C6F5)2 as a frustrated Lewis pair catalyst, a highly enantioselective metal-free hydrogenation of silyl enol ethers was successfully realized to furnish a variety of optically active secondary alcohols in 93-99% yields with 88->99% ee's.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences , Beijing 100190, China.
authors.forename: Simin
authors.initials: S
authors.lastname: Wei
authors.forename: Haifeng
authors.initials: H
authors.lastname: Du