title: Factors associated with malnutrition in patients with head and neck cancer.
abstract: CONCLUSIONS
  Comorbidities as well as T classification were the primary determinants for the nutritional status of patients with head and neck cancer.
  
  
  OBJECTIVE
  We aimed to elucidate the underlying conditions of malnutrition in patients with head and neck cancer.
  
  
  METHODS
  We retrospectively reviewed 726 patients diagnosed with head and neck cancer between 2004 and 2013. Associations between malnutrition and clinical parameters were assessed using univariate and multivariate analyses.
  
  
  RESULTS
  Median body mass index was 21.5 (range 11.6-38.0). According to World Health Organization criteria, the nutritional status of these patients was classified into four groups: underweight (18%), normal (63%), overweight (17%), and obese (1%). Comorbidities were detected in 40% of patients. Multivariate analysis revealed the following factors to be independent factors associated with malnutrition: advanced T stage, metachronous cancer, collagen disease, gastrointestinal disease, and pulmonary disease.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine , Suita, Osaka , Japan.
authors.forename: Yukinori
authors.initials: Y
authors.lastname: Takenaka
authors.forename: Masashi
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Susumu
authors.initials: S
authors.lastname: Nakahara
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Toshimichi
authors.initials: T
authors.lastname: Yasui
authors.forename: Atshushi
authors.initials: A
authors.lastname: Hanamoto
authors.forename: Norihiko
authors.initials: N
authors.lastname: Takemoto
authors.forename: Takahito
authors.initials: T
authors.lastname: Fukusumi
authors.forename: Takahiro
authors.initials: T
authors.lastname: Michiba
authors.forename: Hironori
authors.initials: H
authors.lastname: Cho
authors.forename: Hidenori
authors.initials: H
authors.lastname: Inohara
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D015992:Body Mass Index; D015331:Cohort Studies; D015897:Comorbidity; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000453:epidemiology* / Q000628:therapy; D006801:Humans; D007564:Japan / Q000453:epidemiology; D016015:Logistic Models; D008297:Male; D044342:Malnutrition / Q000175:diagnosis* / Q000453:epidemiology*; D008875:Middle Aged; D015999:Multivariate Analysis; D009752:Nutritional Status; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D017678:Sex Distribution; D055815:Young Adult
keywords: Body mass index; comorbidity; metachronous cancer; nutrition