title: Perioperative physiology and pharmacology in the obese small animal patient.
abstract: OBJECTIVE
  To review the available literature concerning the physiologic and pharmacologic alterations induced by obesity in canine and feline patients and their relevance to perioperative care.
  
  
  METHODS
  Literature review.
  
  
  METHODS
  PubMed, CAB, Web of Science.
  
  
  CONCLUSIONS
  Obesity of cats and dogs is a chronic inflammatory condition that is increasingly prevalent. Similar to the situation in humans, small animal obesity may be associated with changes in endocrine, respiratory, and cardiovascular function. In addition, alteration of body composition in obesity can affect pharmacokinetic variables. Modifications in perioperative care may need to be made for obese dogs and cats, including attention to respiratory and cardiovascular supportive care and drug dose adjustments.
authors.affiliation: Department of Anesthesia, Animal Emergency & Referral Associates, Fairfield, NJ, USA.
authors.forename: Lydia
authors.initials: L
authors.lastname: Love
authors.forename: Martha G
authors.initials: MG
authors.lastname: Cline
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery*; D002415:Cats; D004283:Dog Diseases / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery*; D004285:Dogs; D009765:Obesity / Q000503:physiopathology / Q000662:veterinary*; D019990:Perioperative Care / Q000662:veterinary*
keywords: anesthesia; cats; dogs; obesity; perioperative care