title: The TG/HDL-C Ratio Might Be a Surrogate for Insulin Resistance in Chinese Nonobese Women.
abstract: Obejective. To examine the discriminatory power of triglyceride (TG) and triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-C) for insulin resistance (IR) in a normoglycaemic Chinese population. Methods. The data were collected from 711 individuals. The normoglycaemic individuals were eventually included in the study (n = 533, age: 62.8 ± 6.6 years, male: 56.8%), who were with a fasting plasma glucose < 6.1 mmol/L and without a history of diabetes. IR was defined as the upper quintile (≥1.6) of homeostasis model assessment of IR. Area under the receiver operating characteristic curve (AROC) was used to examine the discriminatory power. Results. The discriminatory power of TG/HDL-C for IR was acceptable in women with a BMI < 24 kg/m(2) or waist circumference < 80 cm (AROCs: 0.718 and 0.713, resp.); however, the discriminatory power was not acceptable in the obese women. TG/HDL-C was not an acceptable marker of IR in men. The discriminatory power of TG for IR was not acceptable in both men and women. Conclusions. The discriminatory power of TG/HDL-C for IR differs by gender and obesity index in the normoglycaemic Chinese population, and TG/HDL-C could discriminate IR in the nonobese and normoglycaemic women.
authors.affiliation: Department of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Jiyun
authors.initials: J
authors.lastname: He
authors.affiliation: Department of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Sen
authors.initials: S
authors.lastname: He
authors.affiliation: Department of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Kai
authors.initials: K
authors.lastname: Liu
authors.affiliation: Department of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Di
authors.initials: D
authors.lastname: Shi
authors.affiliation: Department of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Xiaoping
authors.identifier: 0000-0001-8725-6591
authors.initials: X
authors.lastname: Chen