title: [If the general practitioner has to decide: what is the evidence for the selection of antidepressants?].
abstract: The review summarises the evidence supporting the choice of an antidepressant in primary care. We report current guidance on the choice of antidepressants and the current use of antidepressants in Germany. Evidence for the comparative efficacy of modern antidepressants, such as venlafaxine, duloxetine or agomelatine will be summarized with respect to depressive and accompanying symptoms. Furthermore, differences in adverse events between antidepressants will be reviewed.
authors.affiliation: Klinik für Psychiatrie und Psychotherapie II, Universität Ulm.
authors.forename: L
authors.initials: L
authors.lastname: Staudigl
authors.affiliation: Klinik für Psychiatrie und Psychotherapie II, Universität Ulm.
authors.forename: T
authors.initials: T
authors.lastname: Becker
authors.affiliation: Klinik für Psychiatrie und Psychotherapie II, Universität Ulm.
authors.forename: M
authors.initials: M
authors.lastname: Kösters
mesh_terms: D000081:Acetamides / Q000009:adverse effects / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D015283:Citalopram / Q000009:adverse effects / Q000627:therapeutic use; D003511:Cyclohexanols / Q000009:adverse effects / Q000627:therapeutic use; D003866:Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D000068736:Duloxetine Hydrochloride; D019317:Evidence-Based Medicine; D058006:General Practice; D005858:Germany; D019983:Guideline Adherence; D006801:Humans; D013876:Thiophenes / Q000009:adverse effects / Q000627:therapeutic use; D016896:Treatment Outcome; D000069470:Venlafaxine Hydrochloride; D009281:Naphthalenes
chemical_list: D000081:Acetamides; D000928:Antidepressive Agents; D015283:Citalopram; D003511:Cyclohexanols; D000068736:Duloxetine Hydrochloride; D013876:Thiophenes; D000069470:Venlafaxine Hydrochloride; C084711:agomelatine; D009281:Naphthalenes