title: Urethral polyp-like lesions on prostatic urethra caused by Chlamydia trachomatis infection: a case report.
abstract: Urethral polyp is one of differential diagnoses for the male patients complain of gross-hematuria and/or hematospermia. However, there have been limited numbers of case reports including infectious etiology. Here we reported clinical course and pathological findings of one rare case who was diagnosed and treated as urethral polyp-like lesions on the prostatic urethra caused by Chlamydia trachomatis infection. A 25 year-old man who had a past history of frequent sexual intercourse with unspecified female sexual partner visited the clinic. His chief complaint was gross-hematuria and hematospermia. Endoscopic findings showed that non-specific hemorrhagic polyp-like lesions. To determine the pathological findings including malignant diseases and diagnosis, transurethral resection was performed. Because the pathological findings were similar to those of chlamydial proctitis, additional examination was done. As the results, nucleic acid amplification test of C. trachomatis in urine specimen was positive and immunohistochemical staining of specific chlamydia antigen in resected specimen was also positive. Treatment by orally minocyline 100 mg twice daily for 4 weeks was introduced. After the treatment, symptom was disappeared and nucleic acid amplification test of C. trachomatis in urine specimen turned to be negative. No recurrence was reported 2 years posttreatment.
authors.affiliation: Department of Urology, Hokkaido Social Health Insurance Hospital, Sapporo, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Muranaka
authors.affiliation: Department of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan. Electronic address: stakahas@sapmed.ac.jp.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Takahashi
authors.affiliation: Department of Urology, Hokkaido Social Health Insurance Hospital, Sapporo, Japan.
authors.forename: Takaoki
authors.initials: T
authors.lastname: Hirose
authors.affiliation: Department of Pathology, Hokkaido Social Health Insurance Hospital, Sapporo, Japan.
authors.forename: Atsuo
authors.initials: A
authors.lastname: Hattori
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002690:Chlamydia Infections / Q000150:complications* / Q000188:drug therapy; D002692:Chlamydia trachomatis; D006801:Humans; D008297:Male; D008911:Minocycline / Q000627:therapeutic use; D011127:Polyps / Q000382:microbiology* / Q000601:surgery; D014526:Urethritis / Q000382:microbiology* / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents; D008911:Minocycline
keywords: Chlamydia trachomatis; Hematospermia; Urethral polyp-like lesion