title: Prenatal Diagnosis of Infantile Myofibroma with Postnatal Imaging Correlation.
abstract: Infantile myofibroma is the most common fibrous tumor in infancy. A majority of these lesions are solitary and occur in the head and neck region. Unless visceral sites are involved, the clinical course is typically benign. However, the difficulty in these cases is the differentiation of a benign myofibroma from a solitary malignant neoplasm and determination of visceral involvement. Prenatal diagnosis of this condition is rarely described in the literature, but it does indeed have a role in perinatal management. Our patient was initially identified by prenatal ultrasound with fetal MRI for further characterization of the mass. We present the case of a prenatally diagnosed solitary infantile myofibroma of the lower extremity and highlight the role of prenatal imaging in the diagnosis and treatment of this condition.
authors.affiliation: Cincinnati Fetal Center, Center for Fetal Cellular and Molecular Therapy, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
authors.forename: Alan M
authors.initials: AM
authors.lastname: Coleman
authors.forename: Maria A
authors.initials: MA
authors.lastname: Calvo-Garcia
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Zbojniewicz
authors.forename: Maria
authors.initials: M
authors.lastname: Alonso
authors.forename: Foong-Yen
authors.initials: FY
authors.lastname: Lim
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D047708:Myofibroma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D011247:Pregnancy; D016216:Ultrasonography, Prenatal