title: [Paraneoplastic vasculitis in a patient with cervical cancer].
abstract: BACKGROUND
  Paraneoplastic syndromes precede the dia-gnosis of malignancy. Early detection of paraneoplastic syndrome may lead to detection of malignancy in its early and potentially curable stage. Differential diagnostic process of rare paraneoplastic vasculitis requires multidisciplinary cooperation between rheumatologists, radiologists and oncologists.
  
  
  METHODS
  41 year old female patient with cervical cancer in stage IVB (paraaortic lymphadenopathy) and clinical symptoms of acute vasculitis was admitted to our ward for oncological treatment. Chemoradiotheraphy was initiated concurrently with corticotherapy. During the treatment we observed alleviation of vasculitis related symptoms. Ongoing followup, however, brought no further improvement in vasculitis related symptoms. This lead us to suspicion of recurrence, confirmed on CT scan. Palliative chemotherapy was without any effect and due to worsening performance status was terminated.
  
  
  CONCLUSIONS
  The activity of vasculitis was closely associated with the activity of primary malignant disease. Early recognition of paraneoplastic syndrome may contribute not only to dia-gnosis of malignancy, but is helpful during followup of these patients.
authors.forename: F
authors.initials: F
authors.lastname: Kohútek
authors.forename: A
authors.initials: A
authors.lastname: Rosík
authors.forename: N
authors.initials: N
authors.lastname: Izák
authors.forename: M
authors.initials: M
authors.lastname: Tamášová
authors.forename: B
authors.initials: B
authors.lastname: Bystrický
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D059248:Chemoradiotherapy; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000628:therapy*; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000628:therapy*; D014657:Vasculitis / Q000175:diagnosis / Q000628:therapy*
chemical_list: D000305:Adrenal Cortex Hormones