title: Paroxysmal nocturnal hemoglobinuria presenting as cerebral venous sinus thrombosis: a case report.
abstract: Paroxysmal Nocturnal Hemoglobinuria (PNH) is a rare type of acquired hemolytic anemia that is frequently associated with thrombophilia. It may rarely present with cerebral venous sinus thrombosis, which manifests clinically with signs of raised intracranial pressure and requires lifelong anticoagulation therapy. One such rare presentation was seen in a 28 years old male who had history of recurrent episodes of passing red colored urine and this time presented with severe headache. He was diagnosed to have cerebral venous sinus thrombosis and on further workup was found to be suffering from PNH.
authors.affiliation: Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.
authors.forename: Abdul Rauf
authors.initials: AR
authors.lastname: Memon
authors.affiliation: Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.
authors.forename: Rizwan
authors.initials: R
authors.lastname: Khan
authors.affiliation: Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.
authors.forename: Mohammad Uzair Abdul
authors.initials: MU
authors.lastname: Rauf
authors.affiliation: School of Public Health, Dow University of Health Sciences, Karachi, Pakistan ; Institute of Health and Wellbeing, Public Health, University of Glasgow, 1-Lilybank Gardens, Glasgow G12 8RZ, UK.
authors.forename: Kashif
authors.initials: K
authors.lastname: Shafique