title: Molecular characterization of Streptococcus agalactiae isolates harboring small erm(T)-carrying plasmids.
abstract: Among 1,827 group B Streptococcus (GBS) strains collected between 2006 and 2013 by the French National Reference Center for Streptococci, 490 (26.8%) strains were erythromycin resistant. The erm(T) resistance gene was found in six strains belonging to capsular polysaccharides Ia, III, and V and was carried by the same mobilizable plasmid, which could be efficiently transferred by mobilization to GBS and Enterococcus faecalis recipients, thus promoting a broad dissemination of erm(T).
authors.affiliation: Service de Bactériologie, Centre National de Référence des Streptocoques, Groupe Hospitalier Paris Centre Cochin-Hôtel Dieu-Broca, Assistance Publique Hôpitaux de Paris, Paris, France.
authors.forename: Fabrice
authors.initials: F
authors.lastname: Compain
authors.affiliation: Service de Bactériologie, Centre National de Référence des Streptocoques, Groupe Hospitalier Paris Centre Cochin-Hôtel Dieu-Broca, Assistance Publique Hôpitaux de Paris, Paris, France DHU Risques et Grossesse, Assistance Publique Hôpitaux de Paris, Paris, France INSERM, U1016, Institut Cochin, Paris, France CNRS (UMR 8104), Paris, France Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
authors.forename: Constantin
authors.initials: C
authors.lastname: Hays
authors.affiliation: Service de Bactériologie, Centre National de Référence des Streptocoques, Groupe Hospitalier Paris Centre Cochin-Hôtel Dieu-Broca, Assistance Publique Hôpitaux de Paris, Paris, France DHU Risques et Grossesse, Assistance Publique Hôpitaux de Paris, Paris, France.
authors.forename: Gérald
authors.initials: G
authors.lastname: Touak
authors.affiliation: Service de Bactériologie, Centre National de Référence des Streptocoques, Groupe Hospitalier Paris Centre Cochin-Hôtel Dieu-Broca, Assistance Publique Hôpitaux de Paris, Paris, France DHU Risques et Grossesse, Assistance Publique Hôpitaux de Paris, Paris, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Dmytruk
authors.affiliation: Institut Pasteur, Unité de Biologie des Bactéries Pathogènes à Gram Positif, Paris, France CNRS ERL3526, Paris, France.
authors.forename: Patrick
authors.initials: P
authors.lastname: Trieu-Cuot
authors.affiliation: Service de Bactériologie, Centre National de Référence des Streptocoques, Groupe Hospitalier Paris Centre Cochin-Hôtel Dieu-Broca, Assistance Publique Hôpitaux de Paris, Paris, France DHU Risques et Grossesse, Assistance Publique Hôpitaux de Paris, Paris, France INSERM, U1016, Institut Cochin, Paris, France CNRS (UMR 8104), Paris, France Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
authors.forename: Caroline
authors.initials: C
authors.lastname: Joubrel
authors.affiliation: Service de Bactériologie, Centre National de Référence des Streptocoques, Groupe Hospitalier Paris Centre Cochin-Hôtel Dieu-Broca, Assistance Publique Hôpitaux de Paris, Paris, France DHU Risques et Grossesse, Assistance Publique Hôpitaux de Paris, Paris, France INSERM, U1016, Institut Cochin, Paris, France CNRS (UMR 8104), Paris, France Université Paris Descartes, Sorbonne Paris Cité, Paris, France claire.poyart@cch.aphp.fr.
authors.forename: Claire
authors.initials: C
authors.lastname: Poyart
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D016667:Bacterial Capsules / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics*; D001483:Base Sequence; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D004917:Erythromycin / Q000494:pharmacology*; D008780:Methyltransferases / Q000235:genetics*; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000235:genetics; D017422:Sequence Analysis, DNA; D012703:Serotyping; D013290:Streptococcal Infections / Q000188:drug therapy / Q000382:microbiology; D013292:Streptococcus agalactiae / Q000187:drug effects* / Q000235:genetics*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; C068312:capsular polysaccharide, streptoccal group B type V; D004917:Erythromycin; C111078:ErmTR protein, bacteria; D008780:Methyltransferases