title: Engaging stakeholders in research related to anesthesia and neurodevelopment in children.
abstract: The Fourth PANDA symposium on Anesthesia and Neurodevelopment in Children invited 4 leaders in community engagement and federal government collaboration to share their experiences with overcoming challenges in promoting public health issues. There continues to be emerging evidence from laboratory findings in animal models demonstrating neurotoxic effects and neurodevelopmental changes from early exposure to anesthetic and sedative drugs, but studies in humans have been very limited and inconclusive. Although definitive recommendations for clinical care still cannot be made given the limitations in the clinical data, the need for open communication among clinicians, parents, and other stakeholders is clear. A "top-down, bottom-up" engagement strategy including parents, children, clinicians, government agencies, and community organizations may improve communication and collaboration. To reach the goal of "improving quality, safety, efficiency, and effectiveness of health care in children," clinicians and researchers will need to adopt strategies to engage and partner with stakeholders as coinvestigators who actively participate in efforts to increase anesthetic safety in children. Collaborations with government regulatory administration can improve the efficacy and effectiveness of resource utilization to address public health needs. This session provided an opportunity for open dialog between clinicians, researchers, and community leaders to discuss strategies to engage stakeholders to partake in patient-centered outcomes research on anesthetic neurotoxicity.
authors.affiliation: Department of Anesthesiology, Columbia University Medical Center, Division of Pediatric Anesthesia, Columbia University College of Physicians and Surgeons, New York, NY.
authors.forename: Susan
authors.initials: S
authors.lastname: Lei
authors.forename: Nicholas
authors.initials: N
authors.lastname: Davis
authors.forename: Melissa
authors.initials: M
authors.lastname: Lee
authors.forename: Caleb
authors.initials: C
authors.lastname: Ing
mesh_terms: D000758:Anesthesia / Q000009:adverse effects*; D000777:Anesthetics / Q000009:adverse effects; D035843:Biomedical Research / Q000379:methods*; D002648:Child; D002658:Developmental Disabilities / Q000139:chemically induced*; D006801:Humans; D009420:Nervous System / Q000187:drug effects* / Q000254:growth & development*; D020258:Neurotoxicity Syndromes / Q000209:etiology*; D061214:Patient Safety
chemical_list: D000777:Anesthetics