title: Nuclear magnetic resonance spectroscopy with single spin sensitivity.
abstract: Nuclear magnetic resonance spectroscopy and magnetic resonance imaging at the ultimate sensitivity limit of single molecules or single nuclear spins requires fundamentally new detection strategies. The strong coupling regime, when interaction between sensor and sample spins dominates all other interactions, is one such strategy. In this regime, classically forbidden detection of completely unpolarized nuclei is allowed, going beyond statistical fluctuations in magnetization. Here we realize strong coupling between an atomic (nitrogen-vacancy) sensor and sample nuclei to perform nuclear magnetic resonance on four (29)Si spins. We exploit the field gradient created by the diamond atomic sensor, in concert with compressed sensing, to realize imaging protocols, enabling individual nuclei to be located with Angstrom precision. The achieved signal-to-noise ratio under ambient conditions allows single nuclear spin sensitivity to be achieved within seconds.
authors.affiliation: 1] Institute for Quantum Optics, Albert-Einstein Allee 11, University of Ulm, Ulm D-89081, Germany [2] Center for Integrated Quantum Science and Technology, University of Ulm, Ulm D-89081 Germany [3].
authors.forename: C
authors.initials: C
authors.lastname: Müller
authors.affiliation: 1] Institute for Quantum Optics, Albert-Einstein Allee 11, University of Ulm, Ulm D-89081, Germany [2] Department of Modern Physics, Hefei National Laboratory for Physics Sciences at Microscale, University of Science and Technology of China, Hefei 230026, China [3] Synergetic Innovation Center of Quantum Information and Quantum Physics, University of Science and Technology of China, Hefei 230026, China [4].
authors.forename: X
authors.initials: X
authors.lastname: Kong
authors.affiliation: 1] Center for Integrated Quantum Science and Technology, University of Ulm, Ulm D-89081 Germany [2] Institute for Theoretical Physics, Albert-Einstein Allee 11, University of Ulm, Ulm D-89081, Germany.
authors.forename: J-M
authors.initials: JM
authors.lastname: Cai
authors.affiliation: 1] Institute for Quantum Optics, Albert-Einstein Allee 11, University of Ulm, Ulm D-89081, Germany [2] Center for Integrated Quantum Science and Technology, University of Ulm, Ulm D-89081 Germany.
authors.forename: K
authors.initials: K
authors.lastname: Melentijević
authors.affiliation: Element Six, Ltd., Ascot, Berkshire SL5 8BP, UK.
authors.forename: A
authors.initials: A
authors.lastname: Stacey
authors.affiliation: Element Six, Ltd., Ascot, Berkshire SL5 8BP, UK.
authors.forename: M
authors.initials: M
authors.lastname: Markham
authors.affiliation: Element Six, Ltd., Ascot, Berkshire SL5 8BP, UK.
authors.forename: D
authors.initials: D
authors.lastname: Twitchen
authors.affiliation: Research Center for Knowledge Communities, University of Tsukuba, 1-2 Kasuga, Tsukuba, Ibaraki 305-8550, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Isoya
authors.affiliation: Experimental Physics II, University Leipzig, Linnéstr. 5, 03401 Leipzig, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Pezzagna
authors.affiliation: Experimental Physics II, University Leipzig, Linnéstr. 5, 03401 Leipzig, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Meijer
authors.affiliation: 1] Department of Modern Physics, Hefei National Laboratory for Physics Sciences at Microscale, University of Science and Technology of China, Hefei 230026, China [2] Synergetic Innovation Center of Quantum Information and Quantum Physics, University of Science and Technology of China, Hefei 230026, China.
authors.forename: J F
authors.initials: JF
authors.lastname: Du
authors.affiliation: 1] Center for Integrated Quantum Science and Technology, University of Ulm, Ulm D-89081 Germany [2] Institute for Theoretical Physics, Albert-Einstein Allee 11, University of Ulm, Ulm D-89081, Germany.
authors.forename: M B
authors.initials: MB
authors.lastname: Plenio
authors.affiliation: 1] Institute for Quantum Optics, Albert-Einstein Allee 11, University of Ulm, Ulm D-89081, Germany [2] Center for Integrated Quantum Science and Technology, University of Ulm, Ulm D-89081 Germany.
authors.forename: B
authors.initials: B
authors.lastname: Naydenov
authors.affiliation: 1] Institute for Quantum Optics, Albert-Einstein Allee 11, University of Ulm, Ulm D-89081, Germany [2] Center for Integrated Quantum Science and Technology, University of Ulm, Ulm D-89081 Germany.
authors.forename: L P
authors.initials: LP
authors.lastname: McGuinness
authors.affiliation: 1] Institute for Quantum Optics, Albert-Einstein Allee 11, University of Ulm, Ulm D-89081, Germany [2] Center for Integrated Quantum Science and Technology, University of Ulm, Ulm D-89081 Germany.
authors.forename: F
authors.initials: F
authors.lastname: Jelezko