title: Coccidioides parenchymal cerebral abscess in the setting of lymphoma.
abstract: Coccidioides immitis is a dimorphic fungus endemic to southwestern United States of America. When symptomatic, infection usually results in a subacute respiratory infection. Disseminated coccidioidomycosis occurs in less than 1% of all cases. We report a patient with follicular lymphoma and recent travel to Arizona, who underwent resection of a cerebral Coccidioides abscess. Serology testing was negative. This case highlights the importance of clinical suspicion in patients with neurologic symptoms and travel to an endemic location.
authors.affiliation: Northeast Ohio Medial University, Rootstown, OH, USA.
authors.forename: Benjamin D
authors.initials: BD
authors.lastname: Motley
authors.affiliation: Department of Neurosurgery, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.
authors.forename: Matthew
authors.initials: M
authors.lastname: Grabowski
authors.affiliation: Department of Pathology, Pathology and Laboratory Medicine Institute, L25, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA. Electronic address: praysor@ccf.org.
authors.forename: Richard A
authors.initials: RA
authors.lastname: Prayson
mesh_terms: D000368:Aged; D001922:Brain Abscess / Q000209:etiology* / Q000473:pathology; D003045:Coccidioides / Q000472:pathogenicity*; D003047:Coccidioidomycosis / Q000150:complications*; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use*; D008224:Lymphoma, Follicular / Q000188:drug therapy*; D008297:Male; D000069283:Rituximab / Q000627:therapeutic use*; D014481:United States
chemical_list: D007155:Immunologic Factors; D000069283:Rituximab
keywords: Coccidioides; Follicular lymphoma; Fungus