title: A novel method to estimate the stiffness of carbohydrate polyelectrolyte polymers based on the ionic strength dependence of zeta potential.
abstract: Polysaccharides have received a great deal of attention from, for example, the food, cosmetic and pharmaceutical industries. Their conformations (flexibility/stiffness) span a wide range of conformational flexibilities with large hydrated volumes, these properties are important in relation to polysaccharide structure-function relationships. Perhaps the simplest parameter available to estimate the dilute solution conformation of polysaccharides is the Smidsrød-Haug stiffness parameter (B) where the stiffness of polyelectrolytes can be estimated by measuring the intrinsic viscosity at a number of different ionic strengths. In this paper we propose an alternative method for estimating the Smidsrød-Haug stiffness parameter (B) using the ionic strength dependency of zeta potential. For this purpose we have studied a number of different polysaccharides.
authors.affiliation: Department of Chemical Sciences, School of Applied Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK.
authors.forename: Atiga
authors.initials: A
authors.lastname: Abodinar
authors.affiliation: Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK.
authors.forename: Alan M
authors.initials: AM
authors.lastname: Smith
authors.affiliation: Department of Chemical Sciences, School of Applied Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK. Electronic address: g.morris@hud.ac.uk.
authors.forename: Gordon A
authors.initials: GA
authors.lastname: Morris
mesh_terms: D000464:Alginates / Q000737:chemistry; D048271:Chitosan / Q000737:chemistry; D004573:Electrolytes / Q000737:chemistry*; D020723:Glucuronic Acid / Q000737:chemistry; D006603:Hexuronic Acids / Q000737:chemistry; D008962:Models, Theoretical; D009994:Osmolar Concentration; D010368:Pectins / Q000737:chemistry; D011134:Polysaccharides / Q000737:chemistry*; D012996:Solutions / Q000737:chemistry; D014783:Viscosity
chemical_list: D000464:Alginates; D004573:Electrolytes; D006603:Hexuronic Acids; D011134:Polysaccharides; D012996:Solutions; D010368:Pectins; D020723:Glucuronic Acid; D048271:Chitosan
keywords: Intrinsic viscosity; Persistence length; Polysaccharide conformation; Zeta potential