title: Adipose-derived stem cells: Implications in tissue regeneration.
abstract: Adipose-derived stem cells (ASCs) are mesenchymal stem cells (MSCs) that are obtained from abundant adipose tissue, adherent on plastic culture flasks, can be expanded in vitro, and have the capacity to differentiate into multiple cell lineages. Unlike bone marrow-derived MSCs, ASCs can be obtained from abundant adipose tissue by a minimally invasive procedure, which results in a high number of cells. Therefore, ASCs are promising for regenerating tissues and organs damaged by injury and diseases. This article reviews the implications of ASCs in tissue regeneration.
authors.affiliation: Wakako Tsuji, J Peter Rubin, Kacey G Marra, Adipose Stem Cell Center, Department of Plastic Surgery, University of Pittsburgh, Pittsburgh, PA 15213, United States.
authors.forename: Wakako
authors.initials: W
authors.lastname: Tsuji
authors.affiliation: Wakako Tsuji, J Peter Rubin, Kacey G Marra, Adipose Stem Cell Center, Department of Plastic Surgery, University of Pittsburgh, Pittsburgh, PA 15213, United States.
authors.forename: J Peter
authors.initials: JP
authors.lastname: Rubin
authors.affiliation: Wakako Tsuji, J Peter Rubin, Kacey G Marra, Adipose Stem Cell Center, Department of Plastic Surgery, University of Pittsburgh, Pittsburgh, PA 15213, United States.
authors.forename: Kacey G
authors.initials: KG
authors.lastname: Marra
keywords: Adipose-derived stem cells; Clinical trials; Differentiation; Growth factors; Mesenchymal stem cells; Tissue engineering