title: Botulinum toxin injection for bruxism associated with brain injury: case report.
abstract: Bruxism is involuntary grinding of the teeth and can occur as a complication of brain injury. If untreated, bruxism can lead to severe occlusal trauma. Herein, we present a patient with traumatic brain injury and nocturnal bruxism that was treated with botulinum toxin injection. A 21 yr old male patient with traumatic brain injury from a car accident was admitted to our inpatient rehabilitation unit. He had a history of coma for 2 wk in the intensive care unit. The initial cranial computed tomography scan indicated a superior thalamic hemorrhage. On admission to our department 3 mo postinjury, his mental status was good and he was able to walk without assistance, but he had mild ataxia. He complained about severe teeth grinding at night, which began 2 mo postinjury. Botulinum toxin-A was injected into the masseter muscles (20 U in each muscle) and temporalis muscles (15 U in each muscle) bilaterally. A decrease in bruxism was reported within 3 d. Clinical improvement persisted at assessment 4 mo posttreatment. Botulinum toxin injection can be used as an effective treatment for bruxism associated with brain injury.
authors.affiliation: TSK Rehabilitasyon Merkezi 06530 Bilkent/ANKARA, Turkey. serdarkb@gmail.com.
authors.forename: Serdar
authors.initials: S
authors.lastname: Kesikburun
authors.forename: Rıdvan
authors.initials: R
authors.lastname: Alaca
authors.forename: Berke
authors.initials: B
authors.lastname: Aras
authors.forename: Ilknur
authors.initials: I
authors.lastname: Tuğcu
authors.forename: Arif Kenan
authors.initials: AK
authors.lastname: Tan
mesh_terms: D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D001930:Brain Injuries / Q000150:complications*; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008406:Masseter Muscle; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D020186:Sleep Bruxism / Q000188:drug therapy* / Q000209:etiology; D055815:Young Adult
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A
keywords: botulinum toxin; bruxism; bruxism treatment; case 
  report; complication; masseter muscle; temporalis muscle; tooth clenching; tooth grinding; traumatic brain injury