title: Stress Reactivity in Insomnia.
abstract: This study examined whether individuals with primary insomnia (PI) are more reactive to stress than good sleepers (GS). PI and GS (n = 20 per group), matched on gender and age, completed three nights of polysomnography. On the stress night, participants received a mild electric shock and were told they could receive additional shocks during the night. Saliva samples were obtained for analysis of cortisol and alpha amylase along with self-report and visual analog scales (VAS). There was very little evidence of increased stress on the stress night, compared to the baseline night. There was also no evidence of greater stress reactivity in the PI group for any sleep or for salivary measures. In the GS group, stress reactivity measured by VAS scales was positively associated with an increase in sleep latency in the experimental night on exploratory analyses. Individuals with PI did not show greater stress reactivity compared to GS.
authors.affiliation: a Department of Psychiatry Perelman School of Medicine at the University of Pennsylvania.|b Philadelphia Veterans Administration Medical Center.
authors.forename: Philip R
authors.initials: PR
authors.lastname: Gehrman
authors.affiliation: c Sleep Medicine Institute and Department of Psychiatry , University of Pittsburgh School of Medicine.
authors.forename: Martica
authors.initials: M
authors.lastname: Hall
authors.affiliation: a Department of Psychiatry Perelman School of Medicine at the University of Pennsylvania.
authors.forename: Holly
authors.initials: H
authors.lastname: Barilla
authors.affiliation: c Sleep Medicine Institute and Department of Psychiatry , University of Pittsburgh School of Medicine.
authors.forename: Daniel
authors.initials: D
authors.lastname: Buysse
authors.affiliation: a Department of Psychiatry Perelman School of Medicine at the University of Pennsylvania.
authors.forename: Michael
authors.initials: M
authors.lastname: Perlis
authors.affiliation: d Division of Geriatric Medicine Perelman School of Medicine at the University of Pennsylvania.
authors.forename: Nalaka
authors.initials: N
authors.lastname: Gooneratne
authors.affiliation: a Department of Psychiatry Perelman School of Medicine at the University of Pennsylvania.|b Philadelphia Veterans Administration Medical Center.
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Ross
mesh_terms: D000328:Adult; D004597:Electroshock; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis; D008297:Male; D017286:Polysomnography; D012463:Saliva / Q000737:chemistry; D057566:Self Report; D012890:Sleep / Q000502:physiology; D007319:Sleep Initiation and Maintenance Disorders / Q000150:complications* / Q000503:physiopathology / Q000523:psychology*; D013315:Stress, Psychological / Q000150:complications*; D000516:alpha-Amylases / Q000032:analysis
chemical_list: D000516:alpha-Amylases; D006854:Hydrocortisone