title: Palladium-catalyzed intramolecular oxidative coupling involving double C(sp(2))-H bonds for the synthesis of annulated biaryl sultams.
abstract: The palladium-catalyzed intramolecular oxidative coupling described herein involves a double C(sp(2))-H bond functionalization in sulfonanilides, providing a workable access to biaryl sultams annulated into a six-membered ring that are otherwise difficult to obtain by literature methods. The other synthetic applications of this protocol including the synthesis of biaryl sultams containing a seven-membered ring and analogous sultones are also presented.
authors.affiliation: Department of Pharmaceutical Technology (Process Chemistry), National Institute of Pharmaceutical Education and Research , S. A. S. Nagar, Punjab 160062 India.
authors.forename: Joydev K
authors.initials: JK
authors.lastname: Laha
authors.forename: Krupal P
authors.initials: KP
authors.lastname: Jethava
authors.forename: Neetu
authors.initials: N
authors.lastname: Dayal
mesh_terms: D001713:Biphenyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D006860:Hydrogen Bonding; D009282:Naphthalenesulfonates / Q000138:chemical synthesis* / Q000737:chemistry; D058451:Oxidative Coupling; D010165:Palladium / Q000737:chemistry
chemical_list: D001713:Biphenyl Compounds; D009282:Naphthalenesulfonates; D010165:Palladium; C016768:naphthosultone