title: Systematic review of proximal femoral arthroplasty for non-neoplastic conditions.
abstract: Proximal femoral arthroplasty (PFA) is an established treatment modality following oncological resection. Increasingly, these prostheses are being used for non-neoplastic conditions such as fractures and bone loss associated with septic or aseptic loosening. We performed a systematic review of the literature to determine the failure rates, mortality rates and hip outcome scores when PFAs were used in non-neoplastic conditions. There were 14 studies with an average follow-up of 3.8 years (range 0-14 years) describing 356 PFAs. Re-operation for any reason occurred in 23.8% (85/356) of cases. The most common complications were dislocation (15.7%) and infection (7.6%). The mortality rate ranged from 0% to 40%. PFA provides an acceptable surgical solution when confronted with massive bone loss, but it has a high re-operation rate for dislocation and infection.
authors.affiliation: Leicester Orthopaedics, University Hospitals of Leicester NHS Trust, Leicester, UK.
authors.forename: Muhammad T
authors.initials: MT
authors.lastname: Korim
authors.affiliation: Leicester Orthopaedics, University Hospitals of Leicester NHS Trust, Leicester, UK.
authors.forename: Colin N A
authors.initials: CN
authors.lastname: Esler
authors.affiliation: Leicester Orthopaedics, University Hospitals of Leicester NHS Trust, Leicester, UK; Academic Orthopaedics, Trauma & Sports Medicine, University of Nottingham, Nottingham, UK.
authors.forename: Robert U
authors.initials: RU
authors.lastname: Ashford
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects; D001847:Bone Diseases / Q000601:surgery*; D005269:Femur / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D057068:Periprosthetic Fractures / Q000209:etiology; D011475:Prosthesis Failure; D016459:Prosthesis-Related Infections / Q000209:etiology; D012086:Reoperation
keywords: bone loss; hip revision; megaprosthesis; proximal femoral arthroplasty