title: Biotransformation.
abstract: The field of clinical pharmacology and therapeutics spans a wide spectrum of research areas involving human subjects at both individual and population levels. One of the key concepts relevant to all of these research areas is biotransformation of drug molecules, which can be defined as the chemical modification of drugs within an organism. This issue of the Journal highlights some of the biotransformation pathways and their sources of individual variations.
authors.affiliation: Division of Clinical Pharmacology and Toxicology, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Toronto, Canada.
authors.forename: S
authors.initials: S
authors.lastname: Ito
mesh_terms: D001711:Biotransformation / Q000235:genetics*; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D010597:Pharmacogenetics; D010641:Phenotype; D057285:Precision Medicine