title: Achieving 1% NMR polarization in water in less than 1min using SABRE.
abstract: The development of biocompatible hyperpolarized media is a crucial step towards application of hyperpolarization in vivo. This article describes the achievement of 1% hyperpolarization of 3-amino-1,2,4-triazine protons in water using the parahydrogen induced polarization technique based on signal amplification by reversible exchange (SABRE). Polarization was achieved in less than 1 min.
authors.affiliation: Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Research Institute, Baltimore, Maryland, USA. Electronic address: hzeng6@jhmi.edu.
authors.forename: Haifeng
authors.initials: H
authors.lastname: Zeng
authors.affiliation: Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Research Institute, Baltimore, Maryland, USA.
authors.forename: Jiadi
authors.initials: J
authors.lastname: Xu
authors.affiliation: Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Research Institute, Baltimore, Maryland, USA.
authors.forename: Michael T
authors.initials: MT
authors.lastname: McMahon
authors.affiliation: Bruker UK Limited, Banner Lane, Coventry, UK.
authors.forename: Joost A B
authors.initials: JA
authors.lastname: Lohman
authors.affiliation: Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Research Institute, Baltimore, Maryland, USA. Electronic address: pvanzijl@jhu.edu.
authors.forename: Peter C M
authors.initials: PC
authors.lastname: van Zijl
keywords: Hyperpolarization; Parahydrogen; SABRE