title: [Speckle tracking analysis of left atrial phasic function in patients with hypertension].
abstract: OBJECTIVE
  To assess left atrial (LA) phasic function in hypertension (HT) and to evaluate its relationship with left ventricular diastolic function.
  
  
  METHODS
  Cross-sectional data of 738 population (149 non-HT as control, and 589 HT were further grouped into normal left ventricular diastolic function, mild diastolic dysfunction and moderate/severe diastolic dysfunction sub-groups) in an urban community of Beijing were used. LA global longitudinal strain in late diastole (Sa), early diastole (Se), and total strain (Stot = Sa+ Se), strain rate in late diastole (SRa), systole (SRs), and early diastole (SRe) were measured using off-line speckle-tracking echocardiography analyzing software, and were compared between non-HT and HT groups, and among HT sub-groups.
  
  
  RESULTS
  LA reservoir [Stot: 22.7% ± 5.9% vs. 21.0% ± 5.8%, P = 0.002; SRs: (1.1 ± 0.3)/s vs. (1.0 ± 0.3)/s, P = 0.033] and conduit [Se: 11.1% ± 4.8% vs. 9.6% ± 4.2%, P = 0.001; SRe: (1.0 ± 0.4)/s vs. (0.9 ± 0.3)/s, P < 0.001] indexes were reduced significantly in HT, while contraction (Sa & SRa) indexes were similar to those of non-HT.
  
  
  CONCLUSIONS
  LA reservoir and conduit functions are impaired in HT and deteriorate with left ventricular diastolic dysfunction. LA contraction is preserved in HT with normal and mild diastolic dysfunction while impaired in moderate/severe diastolic dysfunction.
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
authors.forename: Yiang
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
authors.forename: Bao-wei
authors.initials: BW
authors.lastname: Zhang
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
authors.forename: Li-tong
authors.initials: LT
authors.lastname: Qi
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Ma
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Meng
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Huo
mesh_terms: D016279:Atrial Function, Left; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D003971:Diastole; D004452:Echocardiography; D006801:Humans; D006973:Hypertension; D013599:Systole; D018487:Ventricular Dysfunction, Left; D016277:Ventricular Function, Left