title: Knee joint biomechanics and neuromuscular control during gait before and after total knee arthroplasty are sex-specific.
abstract: The future of total knee arthroplasty (TKA) surgery will involve planning that incorporates more patient-specific characteristics. Despite known biological, morphological, and functional differences between men and women, there has been little investigation into knee joint biomechanical and neuromuscular differences between men and women with osteoarthritis, and none that have examined sex-specific biomechanical and neuromuscular responses to TKA surgery. The objective of this study was to examine sex-associated differences in knee kinematics, kinetics and neuromuscular patterns during gait before and after TKA. Fifty-two patients with end-stage knee OA (28 women, 24 men) underwent gait and neuromuscular analysis within the week prior to and one year after surgery. A number of sex-specific differences were identified which suggest a different manifestation of end-stage knee OA between the sexes.
authors.affiliation: School of Biomedical Engineering, Dalhousie University, Halifax, Canada.
authors.forename: Janie L
authors.initials: JL
authors.lastname: Astephen Wilson
authors.affiliation: School of Biomedical Engineering, Dalhousie University, Halifax, Canada; Department of Surgery, Division of Orthopedics, Dalhousie University, Halifax, Canada.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Dunbar
authors.affiliation: School of Biomedical Engineering, Dalhousie University, Halifax, Canada; School of Physiotherapy, Dalhousie University, Halifax, Canada.
authors.forename: Cheryl L
authors.initials: CL
authors.lastname: Hubley-Kozey
mesh_terms: D000368:Aged; D019645:Arthroplasty, Replacement, Knee; D001696:Biomechanical Phenomena; D004576:Electromyography; D005260:Female; D005684:Gait / Q000502:physiology*; D006801:Humans; D007717:Knee / Q000294:innervation*; D007719:Knee Joint / Q000503:physiopathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000294:innervation; D020370:Osteoarthritis, Knee / Q000503:physiopathology* / Q000601:surgery; D025341:Principal Component Analysis; D012737:Sex Factors
keywords: biomechanics; electromyography; gait; knee osteoarthritis; sex; total knee arthroplasty