title: [Specificity of the intradermal Montenegro test in patients infected by Trypanosoma cruzi from different regions of Peru].
abstract: In order to assess the specificity of the leishmanin skin test in Chagas disease patients without clinical history of leishmaniasis, present or former. A sample of 102 persons infected with Trypanosoma cruzi (14 acute cases with parasitological diagnosis and 88 chronic cases) through the demonstration of IgG antibodies by ELISA and indirect immunofluorescence (IIF) were evaluated with leishmanin soluble antigen which contained Leishmania (Viannia) peruviana concentration of 25-30 ug/mL. Only five people showed cutaneous hypersensitivity reaction to the application of the antigen between hours 48 and 72. The Leishmanin skin test evaluated was negative in 97 people infected with T. cruzi, thus specificity of 95.1% was achieved. In conclusion, the intradermal Montenegro test is a simple and effective diagnostic tool that also could be used to discriminate infections by Leishmania or T. cruzi, in Peruvian geographic areas where both parasites are present.
authors.affiliation: Centro Nacional de Salud Pública, Instituto Nacional de Salud, Lima, Perú
authors.forename: Gloria
authors.initials: G
authors.lastname: Minaya-Gómez
authors.affiliation: Centro Nacional de Salud Pública, Instituto Nacional de Salud, Lima, Perú
authors.forename: Silver
authors.initials: S
authors.lastname: Vargas-Apaza
authors.affiliation: Dirección Regional de Salud de San Martin, San Martín, Perú
authors.forename: Yolanda
authors.initials: Y
authors.lastname: Monteza-Zuloeta
authors.affiliation: Dirección Regional de Salud de Amazonas, Amazonas, Perú
authors.forename: Enrique
authors.initials: E
authors.lastname: Purisaca-Morante
authors.affiliation: Dirección Regional de Salud de Arequipa, Arequipa, Perú
authors.forename: Freddy
authors.initials: F
authors.lastname: Delgado-Diaz
mesh_terms: D000293:Adolescent; D000328:Adult; D000913:Antibodies, Protozoan / Q000032:analysis; D014355:Chagas Disease / Q000175:diagnosis* / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D010568:Peru; D012680:Sensitivity and Specificity; D012882:Skin Tests / Q000379:methods; D014349:Trypanosoma cruzi / Q000276:immunology; D055815:Young Adult
chemical_list: D000913:Antibodies, Protozoan