title: Circulating miR-1, miR-133a, and miR-206 levels are increased after a half-marathon run.
abstract: Circulating miRNAs are potential biomarkers that can be important molecules driving cell-to-cell communication.
  
  
  
  To investigate circulating muscle-specific miRNAs in recreational athletes.
  
  
  
  Three miRNAs from whole plasma before and after a half-marathon were analyzed by qPCR.
  
  
  
  MiR-1, -133a, and -206 significantly increased after the race.
  
  
  
  Increased levels of miRNAs after exercise point to potential biomarkers and to the possibility of being functional players following endurance training.
  
  
  
  These miRNAs are potential biomarkers of muscle damage or adaptation to exercise.
authors.affiliation: Pós-Graduação em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília , Brasília, DF , Brazil .
authors.forename: Clarissa P C
authors.initials: CP
authors.lastname: Gomes
authors.forename: Getúlio P
authors.initials: GP
authors.lastname: Oliveira
authors.forename: Bibiano
authors.initials: B
authors.lastname: Madrid
authors.forename: Jeeser A
authors.initials: JA
authors.lastname: Almeida
authors.forename: Octávio L
authors.initials: OL
authors.lastname: Franco
authors.forename: Rinaldo W
authors.initials: RW
authors.lastname: Pereira
mesh_terms: D000328:Adult; D005819:Genetic Markers; D006801:Humans; D008297:Male; D035683:MicroRNAs / Q000097:blood*; D010807:Physical Endurance / Q000235:genetics*; D060888:Real-Time Polymerase Chain Reaction; D012420:Running; D013997:Time Factors; D015854:Up-Regulation
chemical_list: D005819:Genetic Markers; C544547:MIRN1 microRNA, human; C548234:MIRN133 microRNA, human; C546087:MIRN206 microRNA, human; D035683:MicroRNAs
keywords: Exercise; extracellular vesicles; microRNA; plasma; quantitative PCR