title: Palliative care for patients with malignancy and end-stage renal failure on peritoneal dialysis.
abstract: BACKGROUND
  Many patients on peritoneal dialysis experience a poor quality of life because of a high burden of comorbid conditions. Dialysists must pay more attention to reducing a patient's pain and suffering, both physical and psychological and improve the quality of life for the patients as much as possible. A consensus regarding eligibility for palliative care and the delivery of these inventions does not currently exist.
  
  
  OBJECTIVE
  The present study aimed to describe the implementation of palliative care for end-stage renal failure patients on peritoneal dialysis.
  
  
  METHODS
  A report on three cases.
  
  
  METHODS
  This study included three outpatients on peritoneal dialysis who received palliative care and died between January 2008 and June 2010.
  
  
  METHODS
  The patients' comorbidities, nutritional status, and functional status were evaluated using the Charlson comorbidity score, subjective global assessment, and Karnofsky Performance Score index, respectively. The Hamilton depression and Hamilton anxiety scales were also employed. The patients' clinical manifestations and treatments were reviewed.
  
  
  RESULTS
  Each patient displayed 11-16 symptoms. The Charlson comorbidity scores were from 11 to 13, the subjective global assessment indicated that two patients were class assigned to "C" and one to class "B", and the mean Karnofsky index was <40. Among these patients, all experienced depression and two experienced anxiety, Low doses of hypertonic glucose solutions, skin care, psychological services, and tranquillizers were intermittently used to alleviate symptoms, after making the decision to terminate dialysis. The patients died 5 days to 2 months after dialysis withdrawal.
  
  
  CONCLUSIONS
  The considerable burden associated with comorbid conditions, malnutrition, poor functional status, and serious psychological problems are predictors of poor patient prognoses. Withdrawal of dialysis, palliative care, and psychological interventions can reduce patient distress and improve the quality of life before death, with the care provided.
authors.affiliation: Division of Nephrology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
authors.forename: Lv
authors.initials: L
authors.lastname: Jing
authors.affiliation: Division of Nephrology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
authors.forename: Xue
authors.initials: X
authors.lastname: Wu-Jun
authors.affiliation: Division of Nephrology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
authors.forename: Tan
authors.initials: T
authors.lastname: Feng
keywords: Palliative care; peritoneal dialysis; quality of life; symptom burden