title: Growing the seeds sown by Piero Sensi.
abstract: Piero Sensi is probably known primarily for his role in the discovery of rifamycin and for developing it to be a drug of fundamental importance in the treatment of tuberculosis. He has also contributed to promote screening programs of microbial products and research approaches for antibacterial agents that have been further developed up to the present day. This paper reports a sequence of discovery approaches, failures and successes that spans for about 50 years and is still in progress.
authors.affiliation: Biology and Biotechnology, University of Pavia, Pavia, Italy.
authors.forename: Enrico
authors.initials: E
authors.lastname: Selva
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000266:history* / Q000494:pharmacology; D015195:Drug Design; D055808:Drug Discovery / Q000266:history*; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D012294:Rifamycins / Q000737:chemistry / Q000266:history* / Q000494:pharmacology; D014376:Tuberculosis / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D012294:Rifamycins