title: Uterine endometrial carcinoma with trophoblastic differentiation: a case report with literature review.
abstract: Choriocarcinoma is categorized as either gestational or nongestational depending on its origin. Nongestational choriocarcinoma originated in the trophoblastic differentiation is a rare but an aggressive tumor. This article reports a nongestational case of a uterine endometrial carcinoma with trophoblastic differentiation. A 54-year-old woman with a history of atypical genital bleeding that underwent semi-radical hysterectomy, bilateral salpingo-oophrectomy, and pelvic lymph nodes dissection. Pathological investigation showed that the tumor had endometrioid adenocarcinoma and choriocarcinomatous components. Although a series of multimodality treatments including craniotomy were performed, she died of aggressive lung and brain metastases one year after the primary surgery.
authors.forename: T
authors.initials: T
authors.lastname: Seki
authors.forename: N
authors.initials: N
authors.lastname: Yanaihara
authors.forename: Y
authors.initials: Y
authors.lastname: Hirata
authors.forename: M
authors.initials: M
authors.lastname: Fukunaga
authors.forename: T
authors.initials: T
authors.lastname: Tanaka
authors.forename: A
authors.initials: A
authors.lastname: Okamoto
mesh_terms: D018269:Carcinoma, Endometrioid / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D031954:Choriocarcinoma, Non-gestational / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D016889:Endometrial Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D018198:Mixed Tumor, Malignant / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D010052:Ovariectomy; D058994:Salpingectomy; D014057:Tomography, X-Ray Computed