title: Percutaneous closure of ruptured sinus of Valsalva aneurysm: results from a multicentre experience.
abstract: OBJECTIVE
  To evaluate the safety and efficacy of percutaneous closure (PC) using modified double-disc ventricular septal defect (VSD) occluders in patients with ruptured sinus of Valsalva aneurysm (RSVA).
  
  
  RESULTS
  Between 2005 and 2012, 25 patients were enrolled in our study for attempted PC. There were five patients (20%) with RSVA combined with VSD and two (8%) with aortic regurgitation (AR). The median age was 45 years (24-74 years). The QP/QS was 2.4±0.6 (1.6-4.0). The median diameter of lesions was 6 mm (4-8 mm) while the median size of occluders was 8 mm (6-12 mm). Twenty-three patients (92%) underwent PC successfully. Occluders were retrieved in two patients within one week. Trivial residual shunts developed in three and mild occluder-related AR occurred in five at discharge. During a median follow-up of 19 months (6-96 months) all trivial residual shunts vanished and mild occluder-related AR disappeared in four out of five patients. The proportion of patients in NYHA Class III/IV was reduced from 72% at baseline to 12% at the time of last follow-up (p<0.001).
  
  
  CONCLUSIONS
  In selected patients with RSVA, PC using modified double-disc occluders may become a valuable alternative to surgery with encouraging immediate outcomes and midterm results.
authors.affiliation: Department of Cardiology, Changhai Hospital, 2nd Military Medical University, Shanghai, China.
authors.forename: Suxuan
authors.initials: S
authors.lastname: Liu
authors.forename: Xudong
authors.initials: X
authors.lastname: Xu
authors.forename: Xianxian
authors.initials: X
authors.lastname: Zhao
authors.forename: Feng
authors.initials: F
authors.lastname: Chen
authors.forename: Yuan
authors.initials: Y
authors.lastname: Bai
authors.forename: Weiping
authors.initials: W
authors.lastname: Li
authors.forename: Yigang
authors.initials: Y
authors.lastname: Zhang
authors.forename: Cheng
authors.initials: C
authors.lastname: Wang
authors.forename: Jun
authors.initials: J
authors.lastname: Xiang
authors.forename: Guangwei
authors.initials: G
authors.lastname: Wu
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Chen
authors.forename: Yongwen
authors.initials: Y
authors.lastname: Qin
mesh_terms: D000328:Adult; D000368:Aged; D017542:Aneurysm, Ruptured / Q000601:surgery*; D001014:Aortic Aneurysm / Q000601:surgery*; D001021:Aortic Valve / Q000601:surgery; D000082882:Bicuspid Aortic Valve Disease; D005260:Female; D005500:Follow-Up Studies; D006330:Heart Defects, Congenital / Q000601:surgery*; D006349:Heart Valve Diseases / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D055989:Septal Occluder Device / Q000009:adverse effects; D012850:Sinus of Valsalva / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult