title: Microbiological Profile and Drug Sensitivity Pattern among Community Acquired Pneumonia Patients in Tertiary Care Centre in Mangalore, Coastal Karnataka, India.
abstract: BACKGROUND
  Community Acquired Pneumonia (CAP) is the most common respiratory tract infection in day to day practice. The knowledge of organism commonly causative of CAP helps in early empirical treatment initiation.
  
  
  OBJECTIVE
  To study the microbiological profile of patients with community acquired pneumonia and to study drug sensitivity pattern.
  
  
  METHODS
  Hospital based cross sectional study among 100 patients with CAP was conducted in a tertiary care hospital of Southern India. Sputum culture showed that out of 100 patients 39 had an identifiable etiology with 12 patients having evidence of mixed infection.
  
  
  RESULTS
  Micro-organisms isolated in sputum culture were Streptococcus pneumoniae (31%) followed by, Pseudomonas pyogens (15%), Klebsiella pneumoniae (13%). AFB smear was found to be positive in 6 patients. Organisms were found to be sensitive for piperacillin plus tazobactum (41%), aminoglycocides (amikacin-46%, gentamicin-31%), third generation cephalosporins (Cefotaxim-36%, Ceftriaxone-18%) and macrolides (Erythromicin-31%, Azithromycin-18%). Sensitivity to chloramphenicol was observed in 31% sputum culture positive patients. Ciprofloxacin sensitivity was seen among 49%.
  
  
  CONCLUSIONS
  Most of the organisms were found to be sensitive to monotherapy with extended spectrum beta lactamases, third generation cephalosporins, fluroquinolones, macrolides.
authors.affiliation: Associate Professor, Department of Chest Medicine, Kasturba Medical College Mangalore (Manipal University), India .
authors.forename: Vishak K
authors.initials: VK
authors.lastname: Acharya
authors.affiliation: Senior Resident, Department of General Medicine, Kasturba Medical College Mangalore (Manipal University), India .
authors.forename: Mahesha
authors.initials: M
authors.lastname: Padyana
authors.affiliation: Professor and Head, Department of Community Medicine, Kasturba Medical College Mangalore, Mangalore (Manipal University), India .
authors.forename: Unnikrishnan
authors.initials: U
authors.lastname: B
authors.affiliation: Professor and Head, Department of Chest Medicine, Kasturba Medical College Mangalore, Mangalore (Manipal University), India .
authors.forename: Anand
authors.initials: A
authors.lastname: R
authors.affiliation: Associate Professor, Department of Chest Medicine, Kasturba Medical College Mangalore, Mangalore (Manipal University), India .
authors.forename: Preethm R
authors.initials: PR
authors.lastname: Acharya
authors.affiliation: MBBS Student, Kasturba Medical College Mangalore, Mangalore (Manipal University), India .
authors.forename: Divya Jyoti
authors.initials: DJ
authors.lastname: Juneja
keywords: Coastal southern india; Community acquired pneumonia; Drug sensitivity; Microbiological profile