title: Scalarane sesterterpenes from the Paracel Islands marine sponge Hyrtios sp.
abstract: A new scalarane sesterterpene, sesterstamide (1), together with four known sesterterpenes (2-5), were isolated from the Paracel Islands marine sponge Hyrtios sp. The chemical structures were established on the basis of spectroscopic analysis and comparison with known compounds. The cytotoxic and antileishmanial activities of the isolated compounds were also evaluated.
authors.forename: Fan
authors.initials: F
authors.lastname: Yang
authors.forename: Jian-Hong
authors.initials: JH
authors.lastname: Gan
authors.forename: Xiao-Yan
authors.initials: XY
authors.lastname: Liu
authors.forename: Hou-Wen
authors.initials: HW
authors.lastname: Lin
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology; D000981:Antiprotozoal Agents / Q000737:chemistry / Q000494:pharmacology; D062312:Islands; D015394:Molecular Structure; D010140:Pacific Ocean; D011161:Porifera / Q000737:chemistry / Q000378:metabolism*; D054830:Sesterterpenes / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000970:Antineoplastic Agents; D000981:Antiprotozoal Agents; D054830:Sesterterpenes; C000591502:sesterstamide