title: Ruthenium-catalyzed allylic alkylations of chelated enolates using vinyl dioxolanon-2-ones.
abstract: 4-Vinyl-substituted 1,3-dioxolan-2-ones are found to be good substrates for Ru-catalyzed allylic alkylations of chelated amino acid ester enolates. cis-1,3-Dioxolan-2-ones are more reactive than the corresponding trans-isomers. The attack occurs preferentially with regioretention at the position of the leaving group with perfect chirality transfer. Therefore, this protocol is a good complement to the Pd-catalyzed processes, which give only linear products with this type of substrate.
authors.affiliation: Institut für Organische Chemie, Universität des Saarlandes , Campus, Geb. C4.2, D-66123 Saarbruecken, Germany.
authors.forename: Anton
authors.initials: A
authors.lastname: Bayer
authors.forename: Uli
authors.initials: U
authors.lastname: Kazmaier