title: Immune reconstitution inflammatory syndrome in CNS tuberculosis.
abstract: BACKGROUND
  Immune Reconstitution Inflammatory Syndrome (IRIS), an exaggerated inflammatory response with clinical worsening due to immune recovery during treatment, is rare in the immune-competent population.
  
  
  METHODS
  A 5-½-year old immune-competent girl with CNS tuberculosis without HIV who developed paradoxical IRIS.
  
  
  RESULTS
  Response to supportive care along with Anti-tuberculosis treatment.
  
  
  CONCLUSIONS
  IRIS can occur in tuberculosis, even in the immuno-competent.
authors.affiliation: Department of Pediatrics, SAT Hospital, Government Medical College, Thiruvananthapuram, Kerala, India. Correspondence to: Dr KE Elizabeth, Professor of Pediatrics and Superintendent, SAT Hospital, Government Medical College, Thiruvananthapuram, Kerala, India 695 011. elizake@hotmail.com.
authors.forename: K E
authors.initials: KE
authors.lastname: Elizabeth
authors.forename: K
authors.initials: K
authors.lastname: Jubin
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D002675:Child, Preschool; D005260:Female; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome; D011239:Prednisolone / Q000627:therapeutic use; D011859:Radiography; D020306:Tuberculosis, Central Nervous System
chemical_list: D000893:Anti-Inflammatory Agents; D000995:Antitubercular Agents; D011239:Prednisolone