title: Scoring hip osteoarthritis with MRI (SHOMRI): A whole joint osteoarthritis evaluation system.
abstract: BACKGROUND
  To develop a semi-quantitative MR-based hip osteoarthritis (OA) evaluation system (Scoring hip osteoarthritis with MRI, SHOMRI), and to test its reproducibility and face validity.
  
  
  METHODS
  The study involved 98 subjects with informed consent. Three-Tesla MR imaging of hip was performed in three planes with intermediate-weighted fat saturated FSE sequences. Two radiologists assessed cartilage loss, bone marrow edema pattern, subchondral cyst in 10 subregions, and assessed labrum in 4 subregions. In addition, presence or absence of ligamentum teres integrity, paralabral cysts, intra-articular body, and effusion in the hip joint were analyzed using the SHOMRI system. The reproducibility was assessed with intra-class correlation coefficient (ICC), Cohen's Kappa values and percent agreement. SHOMRI scores were correlated with radiographic Kellgren-Lawrence (KL) and OARSI atlas gradings, and clinical parameters, the hip osteoarthritis outcome score (HOOS) and hip range of motion (ROM), using Spearman's rank correlation and ordinal logistic regression.
  
  
  RESULTS
  ICC values were in the excellent range, 0.91 to 0.97. Cohen's Kappa values and percent agreement ranged from 0.55 to 0.79 and 66 to 99%, respectively. SHOMRI demonstrated significant correlations with KL and OARSI gradings as well as with clinical parameters, HOOS and ROM (P < 0.05). Among the SHOMRI features, subchondral cyst and bone marrow edema pattern showed the highest correlation with HOOS and ROM.
  
  
  CONCLUSIONS
  SHOMRI demonstrated moderate to excellent reproducibility and significant correlation with radiographic gradings and clinical parameters.
authors.affiliation: Musculoskeletal Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
authors.forename: Sonia
authors.initials: S
authors.lastname: Lee
authors.affiliation: Musculoskeletal Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Nardo
authors.affiliation: Musculoskeletal Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
authors.forename: Deepak
authors.initials: D
authors.lastname: Kumar
authors.affiliation: Musculoskeletal Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
authors.forename: Cory R
authors.initials: CR
authors.lastname: Wyatt
authors.affiliation: Musculoskeletal Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
authors.forename: Richard B
authors.initials: RB
authors.lastname: Souza
authors.affiliation: Department of Epidemiology & Biostatistics, University of California San Francisco, San Francisco, California, USA.
authors.forename: John
authors.initials: J
authors.lastname: Lynch
authors.affiliation: Department of Epidemiology & Biostatistics, University of California San Francisco, San Francisco, California, USA.
authors.forename: Charles E
authors.initials: CE
authors.lastname: McCulloch
authors.affiliation: Musculoskeletal Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
authors.forename: Sharmila
authors.initials: S
authors.lastname: Majumdar
authors.affiliation: Department of Medicine, University of California at Davis Medical School, Sacramento, California, USA.
authors.forename: Nancy E
authors.initials: NE
authors.lastname: Lane
authors.affiliation: Musculoskeletal Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Link
mesh_terms: D000328:Adult; D000368:Aged; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000503:physiopathology*; D010147:Pain Measurement; D016059:Range of Motion, Articular / Q000502:physiology; D015203:Reproducibility of Results
keywords: hip osteoarthritis, classification system; hip osteoarthritis, diagnosis; hip osteoarthritis, magnetic resonance imaging; hip osteoarthritis, pathology