title: Evaluation of antibiotic allergy: the role of skin tests and drug challenges.
abstract: Antibiotic allergies are frequently reported in both adult and pediatric populations. While a detailed drug history is essential in the evaluation of antibiotic allergy, the history is typically insufficient to determine the presence of a drug allergy. The most readily available diagnostic testing for evaluating antibiotic allergies are drug skin testing and drug challenges. This review will focus on updates in the evaluation of antibiotic allergy utilizing immediate skin tests, delayed intradermal testing, drug patch tests, and drug challenges for both adults and children with histories of antibiotic allergies.
authors.affiliation: The Corvallis Clinic, Corvallis, OR, USA.
authors.forename: Roland
authors.initials: R
authors.lastname: Solensky
authors.forename: David A
authors.initials: DA
authors.lastname: Khan
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D002648:Child; D004342:Drug Hypersensitivity / Q000175:diagnosis*; D006801:Humans; D007428:Intradermal Tests; D018942:Macrolides / Q000009:adverse effects*; D010328:Patch Tests; D010406:Penicillins / Q000009:adverse effects*; D011237:Predictive Value of Tests; D012882:Skin Tests
chemical_list: D000900:Anti-Bacterial Agents; D018942:Macrolides; D010406:Penicillins