title: The association of major patterns of physical activity, sedentary behavior and sleep with health-related quality of life: a cohort study.
abstract: OBJECTIVE
  To examine the prospective association of patterns of physical activity, sedentary behavior and sleep with health-related quality of life (HRQL) in the general population of Spain.
  
  
  METHODS
  A cohort study with 4271 individuals aged ≥ 18 years was recruited in 2008-2010 and followed-up prospectively through 2012. Activity patterns were derived from factor analysis. HRQL was assessed with the SF-12 questionnaire, and suboptimal HRQL was defined as a score below the sex-specific sample median.
  
  
  RESULTS
  Three main activity patterns were identified. A higher adherence to the pattern named "vigorous activity-seated at the computer" was inversely associated with a suboptimal score in the physical-composite summary (PCS) of the SF-12 (multivariate adjusted odds ratio [aOR] for the highest vs. the lowest quartile 0.71; 95% confidence interval [IC] 0.55-0.90; p-trend=0.003). The "light activity-seated for reading" pattern was inversely associated with a suboptimal score in the mental-composite summary (aOR=0.73; 95% CI=0.61-0.89; p-trend=0.002). However, a higher adherence to the "seated for watching TV-daytime sleeping" pattern was directly associated with suboptimal PCS (aOR=1.35; 95% CI=1.10-1.66; p-trend=0.008).
  
  
  CONCLUSIONS
  Patterns including any physical activity were associated with better physical or mental HRQL. However, a pattern defined by sedentary behavior with diurnal sleep showed worse HRQL and should be a priority target of preventive interventions.
authors.affiliation: Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid/IdiPaz, CIBERESP, Madrid, Spain. Electronic address: mpilar.guallar@uam.es.
authors.forename: Pilar
authors.initials: P
authors.lastname: Guallar-Castillón
authors.affiliation: Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid/IdiPaz, CIBERESP, Madrid, Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Bayán-Bravo
authors.affiliation: Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid/IdiPaz, CIBERESP, Madrid, Spain.
authors.forename: Luz M
authors.initials: LM
authors.lastname: León-Muñoz
authors.affiliation: Department of Public Health, School of Medicine, Universidad de la Frontera, Temuco, Chile.
authors.forename: Teresa
authors.initials: T
authors.lastname: Balboa-Castillo
authors.affiliation: Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid/IdiPaz, CIBERESP, Madrid, Spain.
authors.forename: Esther
authors.initials: E
authors.lastname: López-García
authors.affiliation: Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid/IdiPaz, CIBERESP, Madrid, Spain.
authors.forename: Juan Luis
authors.initials: JL
authors.lastname: Gutierrez-Fisac
authors.affiliation: Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid/IdiPaz, CIBERESP, Madrid, Spain.
authors.forename: Fernando
authors.initials: F
authors.lastname: Rodríguez-Artalejo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D015444:Exercise / Q000502:physiology*; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011446:Prospective Studies; D011788:Quality of Life; D057185:Sedentary Behavior; D012890:Sleep / Q000502:physiology*; D013030:Spain; D011795:Surveys and Questionnaires; D055815:Young Adult
keywords: Health-related quality of life; Physical activity; Sedentary behavior; Sleep; Spain