title: Advances in preparation and characterization of chitosan nanoparticles for therapeutics.
abstract: BACKGROUND
  Polymers have been largely explored for the preparation of nanoparticles due to ease of preparation and modification, large gene/drug loading capacity, and biocompatibility. Various methods have been adapted for the preparation and characterization of chitosan nanoparticles.
  
  
  OBJECTIVE
  Focus on the different methods of preparation and characterization of chitosan nanoparticles.
  
  
  METHODS
  Detailed literature survey has been done for the studies reporting various methods of preparation and characterization of chitosan nanoparticles.
  
  
  CONCLUSIONS
  Published database suggests of several methods which have been developed for the preparation and characterization of chitosan nanoparticles as per the application.
authors.affiliation: a Department of Biotechnology , School of Life Sciences, Central University of Rajasthan , Dist-Ajmer , Rajasthan , India.
authors.forename: Krushna
authors.initials: K
authors.lastname: Chandra Hembram
authors.affiliation: b Department of Pharmaceutical Chemistry , Jamia Hamdard University , New Delhi , India.
authors.forename: Shashi
authors.initials: S
authors.lastname: Prabha
authors.affiliation: c Department of Chemistry , University of Delhi , Delhi , India.
authors.forename: Ramesh
authors.initials: R
authors.lastname: Chandra
authors.affiliation: b Department of Pharmaceutical Chemistry , Jamia Hamdard University , New Delhi , India.
authors.forename: Bahar
authors.initials: B
authors.lastname: Ahmed
authors.affiliation: a Department of Biotechnology , School of Life Sciences, Central University of Rajasthan , Dist-Ajmer , Rajasthan , India.
authors.forename: Surendra
authors.initials: S
authors.lastname: Nimesh
mesh_terms: D000107:Acetylation; D011232:Chemical Precipitation; D002686:Chitin / Q000737:chemistry*; D048271:Chitosan / Q000737:chemistry*; D003432:Cross-Linking Reagents / Q000737:chemistry; D004337:Drug Carriers / Q000737:chemistry* / Q000627:therapeutic use; D004655:Emulsions; D005782:Gels; D006801:Humans; D008853:Microscopy / Q000379:methods; D053758:Nanoparticles / Q000737:chemistry* / Q000627:therapeutic use / Q000648:ultrastructure; D010316:Particle Size; D011092:Polyethylene Glycols / Q000737:chemistry*
chemical_list: D003432:Cross-Linking Reagents; D004337:Drug Carriers; D004655:Emulsions; D005782:Gels; D002686:Chitin; D011092:Polyethylene Glycols; D048271:Chitosan
keywords: chitosan; co-precipitation; ionotropic gelation; microemulsion; nanoparticles; polyelectrolyte complex