title: [Non-cystic fibrosis bronchiectasis: diagnosis and treatment].
abstract: Bronchiectasis is the term used for irreversibly dilated airways. Exact epidemiological information on the frequency of bronchiectasis is not available, but the morphological findings are increasingly detected and the associated syndrome is more frequently diagnosed due to improved imaging techniques and increased awareness among chest physicians. The workup of these patients includes a wide panel of investigations guided by patient history and clinical presentation. Despite thorough evaluation the aetiology frequently remains unclear. Chronic infection with Pseudomonas aeruginosa is associated with a severe course of the disease and its detection has impacts on the therapeutic management. Chest physiotherapy, mucoactive substances and antibiotics are the mainstay of therapy. In this review the evaluation of bronchiectasis and the recent therapeutic insights for non-cystic fibrosis bronchiectasis are discussed.
authors.affiliation: Klinik für Pneumologie, UniversitätsSpital Zürich.
authors.forename: L C
authors.initials: LC
authors.lastname: Huber
authors.affiliation: Klinik für Pneumologie, UniversitätsSpital Zürich.
authors.forename: U
authors.initials: U
authors.lastname: Bürgi
authors.affiliation: Klinik für Pneumologie, UniversitätsSpital Zürich.
authors.forename: M M
authors.initials: MM
authors.lastname: Schuurmans
authors.affiliation: Klinik für Pneumologie, UniversitätsSpital Zürich.
authors.forename: C
authors.initials: C
authors.lastname: Benden
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000175:diagnosis / Q000628:therapy; D001987:Bronchiectasis / Q000175:diagnosis* / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D015916:Drainage, Postural; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D026741:Physical Therapy Modalities; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000175:diagnosis / Q000401:mortality; D012138:Respiratory Therapy; D015996:Survival Rate; D014057:Tomography, X-Ray Computed
chemical_list: D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D007155:Immunologic Factors