title: A proteomics-based methodology to investigate the protein corona effect for targeted drug delivery.
abstract: Here we introduce a proteomics methodology based on nanoliquid-chromatography tandem mass spectrometry (nanoLC/MS-MS) to investigate the "protein corona effect for targeted drug delivery", an innovative strategy, which exploits the "protein corona" that forms around nanoparticles in a physiological environment to target cells.
authors.affiliation: Department of Molecular Medicine, "Sapienza" University of Rome, Viale Regina Elena 291, 00161 Rome, Italy. giulio.caracciolo@uniroma1.it.
authors.forename: D
authors.initials: D
authors.lastname: Pozzi
authors.forename: G
authors.initials: G
authors.lastname: Caracciolo
authors.forename: A L
authors.initials: AL
authors.lastname: Capriotti
authors.forename: C
authors.initials: C
authors.lastname: Cavaliere
authors.forename: S
authors.initials: S
authors.lastname: Piovesana
authors.forename: V
authors.initials: V
authors.lastname: Colapicchioni
authors.forename: S
authors.initials: S
authors.lastname: Palchetti
authors.forename: A
authors.initials: A
authors.lastname: Riccioli
authors.forename: A
authors.initials: A
authors.lastname: Laganà
mesh_terms: D000328:Adult; D001798:Blood Proteins / Q000302:isolation & purification* / Q000378:metabolism; D045744:Cell Line, Tumor; D002462:Cell Membrane / Q000378:metabolism; D002853:Chromatography, Liquid / Q000379:methods*; D006801:Humans; D008081:Liposomes / Q000378:metabolism / Q000494:pharmacology*; D011092:Polyethylene Glycols / Q000737:chemistry; D040901:Proteomics / Q000379:methods*; D053719:Tandem Mass Spectrometry / Q000379:methods*; D055815:Young Adult
chemical_list: D001798:Blood Proteins; D008081:Liposomes; D011092:Polyethylene Glycols