title: Primary mediastinal adenocarcinoma originating from a calcified nodule.
abstract: Primary mediastinal adenocarcinoma is rare, but its originating from a calcified nodule is even more unusual. We present herein a 55-year-old female with a superior mediastinal mass, first discovered 2 years prior that changed dramatically from its original appearance as a calcified nodule. The mass was completely resected, and histopathological examination revealed a primary adenocarcinoma. The patient has been disease-free for over 13 months since surgery. To the best of our knowledge, this is the first reported case of mediastinal adenocarcinoma to demonstrate such a surprising course of development.
authors.affiliation: Department of Lung Cancer Surgery, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital Tianjin 30052, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Chen
authors.affiliation: Department of Lung Cancer Surgery, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital Tianjin 30052, China.
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Qiu
authors.affiliation: Department of Lung Cancer Surgery, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital Tianjin 30052, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Lung Cancer Surgery, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital Tianjin 30052, China.
authors.forename: Yanjie
authors.initials: Y
authors.lastname: Qiao
authors.affiliation: Department of Lung Cancer Surgery, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital Tianjin 30052, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Shi
authors.affiliation: Department of Lung Cancer Surgery, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital Tianjin 30052, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Chen
authors.affiliation: Department of Lung Cancer Surgery, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital Tianjin 30052, China.
authors.forename: Qinghua
authors.initials: Q
authors.lastname: Zhou
keywords: Mediastinal adenocarcinoma; calcified nodule; surgery