title: Respiratory sinus arrhythmia in Chagas disease.
abstract: We applied the respiratory sinus arrhythmia (RSA) quantification algorithm to 24-hour ECG recordings of Chagas disease (ChD) patients with (G1, n=148) and without left ventricular dysfunction (LVD) (G2, n=33), and in control subjects (G0, n=28). Both ChD groups displayed a reduced RSA index; G1=299 (144-812); G2=335 (162-667), p=0.011, which was correlated with vagal indexes of heart rate variability analysis. RSA index is a marker of vagal modulation in ChD patients.
authors.affiliation: Faculdade de Medicina and Hospital das Clínicas, Universidade Federal de Minas Gerais, Avenida Professor Alfredo Balena, 190-Santa Efigênia, Belo Horizonte, 30130-100 Minas Gerais, Brazil.
authors.forename: Victor Ribeiro
authors.initials: VR
authors.lastname: Neves
authors.affiliation: Faculty of Medicine, Institute of Clinical Medicine, University of Oulu, Aapistie 5 A, P.O. Box 5000, 90014 Oulu, Finland.
authors.forename: Mirja
authors.initials: M
authors.lastname: Peltola
authors.affiliation: Faculty of Medicine, Institute of Clinical Medicine, University of Oulu, Aapistie 5 A, P.O. Box 5000, 90014 Oulu, Finland.
authors.forename: Heikki
authors.initials: H
authors.lastname: Huikuri
authors.affiliation: Faculdade de Medicina and Hospital das Clínicas, Universidade Federal de Minas Gerais, Avenida Professor Alfredo Balena, 190-Santa Efigênia, Belo Horizonte, 30130-100 Minas Gerais, Brazil.
authors.forename: Manoel Otávio da Costa
authors.initials: MO
authors.lastname: Rocha
authors.affiliation: Faculdade de Medicina and Hospital das Clínicas, Universidade Federal de Minas Gerais, Avenida Professor Alfredo Balena, 190-Santa Efigênia, Belo Horizonte, 30130-100 Minas Gerais, Brazil. Electronic address: tom@hc.ufmg.br.
authors.forename: Antonio Luiz
authors.initials: AL
authors.lastname: Ribeiro
mesh_terms: D000328:Adult; D000465:Algorithms; D014355:Chagas Disease / Q000150:complications / Q000503:physiopathology*; D003430:Cross-Sectional Studies; D004562:Electrocardiography; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D065809:Respiratory Sinus Arrhythmia / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000503:physiopathology
keywords: Autonomic nervous system; Chagas disease; Heart rate variability; Respiratory sinus arrhythmia; Vagal modulation