title: Formation of and countermeasures for subacute coronary stent thrombosis in elderly diabetic patients.
abstract: The aim of this study was to evaluate and investigate the pathogenetic mechanism and countermeasures of subacute thrombosis (SAT) after coronary stenting in elderly diabetic patients. The clinical characteristics and pathogenetic mechanisms in 3 cases of SAT after stent implantations in elderly diabetic patients were retrospectively examined to determine the treatment strategies for SAT. Among 98 patients with diabetes who had coronary stents implanted or were >60 years of age, three (3.06%) had SAT. One case of SAT was diagnosed by angiography; coronary balloon dilatation, thrombolysis, and re-perfusion resulted in full recovery in this case. The second case involved potential SAT, and in the third case, SAT was not ruled out. Two cases were characteristic of ST-segment elevation myocardial infarction, and one case, in which SAT was not ruled out, resulted in sudden death. SAT within a stent may be related to intraoperative stent malapposition caused by a grade C lesion, age, diabetes, chronic total occlusion, or postoperative irregular administration of medication.
authors.affiliation: Department of Cardiology, Yongchuang Hospital, Chongqing Medical University, Chongqing, China.
authors.forename: Z-F
authors.initials: ZF
authors.lastname: Li
authors.affiliation: Department of Cardiology, People's Hospital of Tongliang County, Chongqing, China lzf56888@163.com.
authors.forename: Y-P
authors.initials: YP
authors.lastname: Zhang
authors.affiliation: Department of Cardiology, People's Hospital of Tongliang County, Chongqing, China.
authors.forename: Z-Q
authors.initials: ZQ
authors.lastname: Qin
authors.affiliation: Department of Cardiology, Yongchuang Hospital, Chongqing Medical University, Chongqing, China.
authors.forename: X-L
authors.initials: XL
authors.lastname: Li
authors.affiliation: Department of Cardiology, Yongchuang Hospital, Chongqing Medical University, Chongqing, China.
authors.forename: C-H
authors.initials: CH
authors.lastname: Gao
authors.affiliation: Department of Cardiology, Yongchuang Hospital, Chongqing Medical University, Chongqing, China.
authors.forename: S
authors.initials: S
authors.lastname: Yang
authors.affiliation: Department of Cardiology, Yongchuang Hospital, Chongqing Medical University, Chongqing, China.
authors.forename: Z-J
authors.initials: ZJ
authors.lastname: Chen
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D003327:Coronary Disease / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D003328:Coronary Thrombosis / Q000209:etiology* / Q000628:therapy*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D017809:Fatal Outcome; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D015607:Stents / Q000009:adverse effects*; D016896:Treatment Outcome; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D005343:Fibrinolytic Agents; D014568:Urokinase-Type Plasminogen Activator