title: Molecular function of counting the numbers 1 and 2 exhibited by a sulfoneamidohelicene tetramer.
abstract: The sulfoneamidohelicene tetramer in solution exhibits different molecular responses to the same cooling stimulus delivered once and twice under thermal hysteresis conditions. Its random-coil state at a high temperature was cooled and maintained at a given temperature for which its molecules remained in a random coil (first cooling); the resulting solution was heated and cooled, after which a helix dimer formed (second cooling). Such a property can be regarded as a molecular function of counting the numbers 1 and 2.
authors.affiliation: Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University 6-3 Aoba, Sendai 980-8578 (Japan), Fax: (+81) 22-795-6811.
authors.forename: Masanori
authors.initials: M
authors.lastname: Shigeno
authors.forename: Yo
authors.initials: Y
authors.lastname: Kushida
authors.forename: Yuta
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Masahiko
authors.initials: M
authors.lastname: Yamaguchi
mesh_terms: D019281:Dimerization; D008968:Molecular Conformation; D013449:Sulfonamides / Q000737:chemistry*; D013696:Temperature
chemical_list: D013449:Sulfonamides
keywords: counting; helical structures; sulfonamides; thermal hysteresis; threshold