title: Serine-threonine kinases in TCR signaling.
abstract: T lymphocyte proliferation and differentiation are controlled by signaling pathways initiated by the T cell antigen receptor. Here we explore how key serine-threonine kinases and their substrates mediate T cell signaling and coordinate T cell metabolism to meet the metabolic demands of participating in an immune response.
authors.affiliation: Instituto Investigación Sanitaria/Hospital Universitario de la Princesa, Universidad Autónoma de Madrid, Madrid, Spain.
authors.forename: María N
authors.initials: MN
authors.lastname: Navarro
authors.affiliation: The College of Life Sciences, Division of Cell Signalling and Immunology, University of Dundee, Dundee, UK.
authors.forename: Doreen A
authors.initials: DA
authors.lastname: Cantrell
mesh_terms: D002454:Cell Differentiation / Q000276:immunology*; D049109:Cell Proliferation / Q000502:physiology*; D006801:Humans; D008213:Lymphocyte Activation / Q000276:immunology; D017346:Protein Serine-Threonine Kinases / Q000276:immunology*; D011948:Receptors, Antigen, T-Cell / Q000276:immunology*; D015398:Signal Transduction / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D011948:Receptors, Antigen, T-Cell; D017346:Protein Serine-Threonine Kinases