title: Feasibility and preliminary efficacy of a web-based smoking cessation intervention for HIV-infected smokers: a randomized controlled trial.
abstract: OBJECTIVE
  To evaluate the feasibility and preliminary efficacy of a Web-based tobacco treatment for persons living with HIV (PLWH).
  
  
  METHODS
  Prospective, randomized controlled trial.
  
  
  METHODS
  HIV-care center in the Bronx, New York.
  
  
  METHODS
  Eligibility criteria included HIV infection, current tobacco usage, interest in quitting, and access to a computer with internet. One hundred thirty-eight subjects enrolled, and 134 completed the study.
  
  
  METHODS
  Positively Smoke Free on the Web (PSFW), an 8-session, 7-week targeted tobacco treatment program for PLWH, was compared with standard care (brief advice to quit and self-help brochure). All subjects were offered nicotine patches.
  
  
  METHODS
  The main feasibility outcomes were number of sessions logged into, number of Web pages visited, number of interactive clicks, and total time logged in. The main efficacy outcome was biochemically verified, 7-day point prevalence abstinence 3 months after intervention.
  
  
  RESULTS
  PSFW subjects logged into a mean of 5.5 of 8 sessions and 26.2 of 41 pages. They executed a mean of 10 interactive clicks during a mean total of 59.8 minutes logged in. Most required reminder phone calls to complete the sessions. Educational level, anxiety score, and home access of the Web site were associated with Web site usage. Ten percent of the PSFW group vs. 4.3% of controls achieved the abstinence end point. Among those who completed all 8 sessions, 17.9% were abstinent, and among women completers, 30.8% were abstinent.
  
  
  CONCLUSIONS
  Web-based treatment is a feasible strategy for PLWH smokers, and preliminary findings suggest therapeutic efficacy.
authors.affiliation: *Department of Medicine, AIDS Center/Division of Infectious Diseases, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY; †Department of Medicine, Center for Health Communications Research, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; and ‡Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Shuter
authors.forename: Daniela A
authors.initials: DA
authors.lastname: Morales
authors.forename: Shannon E
authors.initials: SE
authors.lastname: Considine-Dunn
authors.forename: Lawrence C
authors.initials: LC
authors.lastname: An
authors.forename: Cassandra A
authors.initials: CA
authors.lastname: Stanton
mesh_terms: D001944:Breath Tests; D002248:Carbon Monoxide / Q000032:analysis; D005260:Female; D015658:HIV Infections / Q000523:psychology*; D015497:HIV-1; D006801:Humans; D020407:Internet / Q000592:standards*; D016015:Logistic Models; D008297:Male; D009519:New York City; D011446:Prospective Studies; D016540:Smoking Cessation / Q000379:methods* / Q000523:psychology; D011795:Surveys and Questionnaires
chemical_list: D002248:Carbon Monoxide