title: Three-dimensional flash flow microreactor for scale-up production of monodisperse PEG-PLGA nanoparticles.
abstract: We present a pressure-tolerant 3D parallel polyimide (PI) film microreactor operating at up to ~160 bars with direct 3D flow focusing geometry for mass production of PEG-PLGA nanoparticles in a ~10(1) gram-scale (g h(-1)).
authors.affiliation: Center of Applied Microfluidic Chemistry (CAMC), Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, 790-784, Republic of Korea. dpkim@postech.ac.kr.
authors.forename: Kyoung-Ik
authors.initials: KI
authors.lastname: Min
authors.forename: Do Jin
authors.initials: DJ
authors.lastname: Im
authors.forename: Hyune-Jea
authors.initials: HJ
authors.lastname: Lee
authors.forename: Dong-Pyo
authors.initials: DP
authors.lastname: Kim
mesh_terms: D007094:Imides / Q000737:chemistry; D055616:Microtechnology / Q000295:instrumentation; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D011091:Polyesters / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry; D013499:Surface Properties
chemical_list: D007094:Imides; D011091:Polyesters; D011108:Polymers; C000589473:polyethylene glycol-poly(lactide-co-glycolide); D011092:Polyethylene Glycols