title: Ratiometric fluorescent probe for biothiol in aqueous medium with fluorescent organic nanoparticles.
abstract: A dipodal rhodamine-based mercury complex have been designed and synthesized, for the selective detection of 3-mercaptopropionic acid (MPA). To avoid the poor solubility of rhodamine-based ligand in pure water, the Hg(2+) complex of fluorescent organic nanoparticles (FONs) of ligand have been developed using reprecipitation method and the formation of 1:1 complex has been confirmed with various spectroscopic techniques. The resultant chemosensor can detect MPA in a concentration range of 60 nM-1 μM (in buffered aqueous medium) with detection limit of 60 nM.
authors.affiliation: Department of Chemistry, Indian Institute of Technology Ropar (IIT Ropar), Rupnagar, Punjab 140001, India.
authors.forename: Vimal K
authors.initials: VK
authors.lastname: Bhardwaj
authors.affiliation: Department of Chemistry, Indian Institute of Technology Ropar (IIT Ropar), Rupnagar, Punjab 140001, India.
authors.forename: Hemant
authors.initials: H
authors.lastname: Sharma
authors.affiliation: Department of Chemistry, Indian Institute of Technology Ropar (IIT Ropar), Rupnagar, Punjab 140001, India. Electronic address: nsingh@iitrpr.ac.in.
authors.forename: Narinder
authors.initials: N
authors.lastname: Singh
mesh_terms: D015097:3-Mercaptopropionic Acid / Q000737:chemistry*; D002021:Buffers; D005456:Fluorescent Dyes / Q000737:chemistry*; D007287:Inorganic Chemicals / Q000737:chemistry; D007477:Ions; D008024:Ligands; D008628:Mercury / Q000737:chemistry; D008670:Metals / Q000737:chemistry; D053758:Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D009930:Organic Chemicals / Q000737:chemistry*; D012235:Rhodamines / Q000737:chemistry; D012995:Solubility; D012997:Solvents / Q000737:chemistry; D013053:Spectrophotometry / Q000379:methods; D013696:Temperature; D014867:Water / Q000737:chemistry
chemical_list: D002021:Buffers; D005456:Fluorescent Dyes; D007287:Inorganic Chemicals; D007477:Ions; D008024:Ligands; D008670:Metals; D009930:Organic Chemicals; D012235:Rhodamines; D012997:Solvents; D014867:Water; D015097:3-Mercaptopropionic Acid; D008628:Mercury
keywords: Dipodal; Fluorescent organic nanoparticles; Nanomolar detection; Ratiometric