title: Comparison of Tc-99m pertechnetate images with dual-phase Tc 99m MIBI and SPECT images in primary hyperparathyroidism.
abstract: BACKGROUND
  The purpose of this study was to evaluate the value of Tc-99m pertechnetate planar, dual-phase MIBI and MIBI-SPECT images in the determination and localization of parathyroid lesions.
  
  
  METHODS
  In this study, 38 patients who underwent operation for primary hyperparathyroidism were included. Tc-99m pertechnetate planar-pinhole imaging of the neck and then MIBI planar and SPECT images in supine position was performed. Late SPECT images were acquired 120 minutes after the injection. Early and late MIBI images were quantitatively evaluated.
  
  
  RESULTS
  Of the 38 patients, 30 of them had adenoma, 2 patients had hyperplasia and 6 of them were normal on planar images. Thirty-four of 38 patients were positive on SPECT images. SPECT images of the patients with positive results were matched with pathology results.
  
  
  CONCLUSIONS
  As a result, Tc-99m pertechnetate planar-pinhole, Tc-99m MIBI planar and SPECT images are useful for localization of parathyroid lesions especially in multinodular thyroid gland. However, US or CT images are necessary for more accurate localization and Tc-99m pertechnetate images are useful for interpreting and comparing with the early and late MIBI images.
authors.affiliation: Department of Nuclear Medicine, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey.
authors.forename: Sait
authors.initials: S
authors.lastname: Sager
authors.affiliation: Department of Nuclear Medicine, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey.
authors.forename: Hojjat
authors.initials: H
authors.lastname: Shafipour
authors.affiliation: Department of Nuclear Medicine, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey.
authors.forename: Sertac
authors.initials: S
authors.lastname: Asa
authors.affiliation: Department of Nuclear Medicine, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey.
authors.forename: Sabire
authors.initials: S
authors.lastname: Yılmaz
authors.affiliation: Department of Endocrine Surgery, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey.
authors.forename: Serkan
authors.initials: S
authors.lastname: Teksöz
authors.affiliation: Department of Nuclear Medicine, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey.
authors.forename: Cetin
authors.initials: C
authors.lastname: Onsel
keywords: MIBI; Single-photon emission computed tomography; TC-99m pertechnetate; primary hyperparathyroidism; scintigraphy