title: [Analysis for related factors of upper urinary tract deterioration in patients with spinal cord injury].
abstract: OBJECTIVE
  To evaluate the related factors of upper urinary tract deterioration in spinal cord injured patients.
  
  
  METHODS
  Medical records of spinal cord injured patients from Jan.2002 to Sep.2009 were retrospectively reviewed. All the patients were divided into the upper urinary tract deterioration group and non-deterioration group according to the diagnostic criteria. Indexes such as demographic characteristic (gender, age), spinal cord injury information (cause, level, completeness), statuses of urinary tract system (bladder management, urine routine, urine culture, ultrasound, serum creatinine, fever caused by urinary tract infection) and urodynamics information(bladder compliance, bladder stability, bladder sensation, detrusor sphincter dyssynergia, detrusor leak point pressure, maximum cystometric capacity, relative safe bladder capacity, maximum flow rate, maximum urethra closure pressure) were compared between the two groups.Then Logistic regression analysis were performed.
  
  
  RESULTS
  There was significantly difference between the two groups in spinal cord injury level(χ(2) = 8.840, P = 0.031),bladder management(χ(2) = 11.362, P = 0.045), urinary rutine(χ(2) = 17.983, P = 0.000), fever caused by urinary tract infection(χ(2)= 64.472, P = 0.000), bladder compliance(χ(2) = 6.531, P = 0.011), bladder sensation(χ(2) = 11.505, P = 0.009), maximum cystometric capacity(t = 2.209, P = 0.043), and detrusor-sphincter dyssynergia(χ(2) = 4.247, P = 0.039). The multiple-factor non-conditional Logistic regression analysis showed that bladder management (OR = 1.114, P = 0.006), fever caused by urinary tract infection(OR = 1.018,P = 0.000), bladder compliance (OR = 1.588, P = 0.040) and detrusor-sphincter dyssynergia(OR = 1.023, P = 0.034) were the key factors of upper urinary tract deterioration in spinal cord injured patients.
  
  
  CONCLUSIONS
  Urinary tract infection, lower bladder compliance, detrusor-sphincter dyssynergia and unreasonable bladder management are the risk factors of upper urinary tract deterioration in spinal cord injured patients.
authors.affiliation: Department of Urology,China Rehabilitation Research Center Beijing Bo Ai Hospital; Department of Urology, Capital Medical University, Beijing 100068,China.
authors.forename: Hua-fang
authors.initials: HF
authors.lastname: Jing
authors.affiliation: Department of Urology,China Rehabilitation Research Center Beijing Bo Ai Hospital; Department of Urology, Capital Medical University, Beijing 100068,China.
authors.forename: Li-min
authors.initials: LM
authors.lastname: Liao
authors.affiliation: Department of Urology,China Rehabilitation Research Center Beijing Bo Ai Hospital; Department of Urology, Capital Medical University, Beijing 100068,China.
authors.forename: Guang
authors.initials: G
authors.lastname: Fu
authors.affiliation: Department of Urology,China Rehabilitation Research Center Beijing Bo Ai Hospital; Department of Urology, Capital Medical University, Beijing 100068,China.
authors.forename: Juan
authors.initials: J
authors.lastname: Wu
authors.affiliation: Department of Urology,China Rehabilitation Research Center Beijing Bo Ai Hospital; Department of Urology, Capital Medical University, Beijing 100068,China.
authors.forename: Yan-he
authors.initials: YH
authors.lastname: Ju
authors.affiliation: Department of Urology,China Rehabilitation Research Center Beijing Bo Ai Hospital; Department of Urology, Capital Medical University, Beijing 100068,China.
authors.forename: Guo-qing
authors.initials: GQ
authors.lastname: Chen
mesh_terms: D006801:Humans; D012189:Retrospective Studies; D012307:Risk Factors; D013119:Spinal Cord Injuries / Q000503:physiopathology*; D001745:Urinary Bladder Diseases / Q000453:epidemiology*; D014563:Urodynamics