title: Reconstruction of irradiated mandible after segmental resection of osteoradionecrosis-a technique employing a microvascular latissimus dorsi flap and subsequent particulate iliac bone grafting.
abstract: The fibula osteocutaneous flap has revolutionized the options of mandibular segmental defect bridging in osteoradionecrosis (ORN). In selected cases, however, the fibula flap is not an option because of atherosclerosis or other features that compromise the vascularity of the lower leg and foot. The aim of this study is to present an alternative method of mandibular segmental reconstruction employing a latissimus dorsi (LD) flap and subsequent particulate iliac free bone graft reconstruction. In 15 patients with ORN, a mandibular segmental defect was bridged with a reconstruction plate, and the defect site was primed with a LD musculocutaneous flap wrapped around the reconstruction plate to bring in vascularized tissue and optimize healing conditions for a subsequent particulate iliac free bone graft reconstruction. The management of defect closure was successful in all 15 patients. Twelve patients had a subsequent bone grafting from the posterior ileum for repair of defects up to 14 cm length. Three patients had no bone graft for various reasons. In three patients dental rehabilitation was achieved with implant supported prosthodontic appliances. Ten patients met the success criteria of uneventful graft healing with restitution of osseous continuity, mandibular height, symmetry and function, and avoidance of reconstruction plate fracture.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Rigshospitalet, University of Copenhagen.
authors.forename: Soren
authors.initials: S
authors.lastname: Hillerup
authors.affiliation: Department of Plastic and Reconstructive Surgery, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
authors.forename: Jens Jorgen
authors.initials: JJ
authors.lastname: Elberg
authors.affiliation: Department of Oral and Maxillofacial Surgery, Hospital of South-West Denmark, Esbjerg, Denmark.
authors.forename: Jens Jorgen
authors.initials: JJ
authors.lastname: Thorn
authors.affiliation: Department of Plastic and Reconstructive Surgery, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
authors.forename: Mikael
authors.initials: M
authors.lastname: Andersen
keywords: latissimus dorsi flap; mandible; particulate iliac bone grafting; reconstruction; segmental defect