title: Macular Changes Correlate with the Degree of Acute Anterior Uveitis in Patients with Spondyloarthropathy.
abstract: OBJECTIVE
  To evaluate the correlation between anterior chamber inflammation and the central foveal thickness of the retina in a homogenous uveitic group (seronegative spondyloarthropathy (subgroup: ankylosing spondylitis)) of patients with the first acute anterior unilateral uveitic attack.
  
  
  METHODS
  Central foveal thickness (FT) and perifoveal retinal thickness were recorded by optical coherence tomography (Optovue RTVue-100), and the difference between the two eyes was calculated. Statistical analysis was performed by Mathworks Matlab software. Anterior chamber inflammation was measured by laser flare photometry (Kowa FM-600).
  
  
  RESULTS
  A statistically significant (p < .05) increase was found in retinal thickness in all OCT subfields in acute anterior uveitic eyes compared to healthy fellow eyes. There was a linear correlation between the degree of inflammation (laser flare photometry values) and central foveal thickness (r = .900, p < .001).
  
  
  CONCLUSIONS
  We could demonstrate close correlation between macular thickness and inflammation in anterior uveitic patients with spondyloarthropathy.
authors.affiliation: a Department of Ophthalmology , Semmelweis University , Budapest , Hungary .
authors.forename: Zsuzsanna
authors.initials: Z
authors.lastname: Szepessy
authors.affiliation: b Department of Photogrammetry and Geoinformatics , Budapest University of Technology and Economics , Budapest , Hungary , and.
authors.forename: Árpád
authors.initials: Á
authors.lastname: Barsi
authors.affiliation: c Department of Ophthalmology , Semmelweis University , Budapest , Hungary.
authors.forename: János
authors.initials: J
authors.lastname: Németh
mesh_terms: D000208:Acute Disease; D000328:Adult; D058452:Axial Length, Eye / Q000473:pathology; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010783:Photometry; D011446:Prospective Studies; D013167:Spondylitis, Ankylosing / Q000175:diagnosis* / Q000503:physiopathology; D041623:Tomography, Optical Coherence; D014606:Uveitis, Anterior / Q000175:diagnosis* / Q000503:physiopathology; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult
keywords: Inflammation; macular thickness; optical coherence tomography; spondyloarthropathy; uveitis