title: Single functionalized graphene oxide reconstitutes kinesin mediated intracellular cargo transport and delivers multiple cytoskeleton proteins and therapeutic molecules into the cell.
abstract: Here, we report a covalently functionalized graphene oxide with Tris-(nitrilo Tris-acetic acid) (TGO), which can reconstitute kinesin mediated intracellular cargo transport, and deliver multiple proteins and therapeutic antimitotic dodecapeptide peptides into the cancer cell.
authors.affiliation: Chemistry Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Jadavpur, Kolkata-700032, West Bengal, India. sghosh@iicb.res.in.
authors.forename: Batakrishna
authors.initials: B
authors.lastname: Jana
authors.forename: Atanu
authors.initials: A
authors.lastname: Biswas
authors.forename: Saswat
authors.initials: S
authors.lastname: Mohapatra
authors.forename: Abhijit
authors.initials: A
authors.lastname: Saha
authors.forename: Surajit
authors.initials: S
authors.lastname: Ghosh
mesh_terms: D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D016547:Kinesins / Q000737:chemistry* / Q000378:metabolism; D061986:MCF-7 Cells; D008870:Microtubules / Q000378:metabolism; D053758:Nanoparticles / Q000737:chemistry / Q000633:toxicity; D010087:Oxides / Q000737:chemistry; D010455:Peptides / Q000737:chemistry / Q000378:metabolism; D059008:Time-Lapse Imaging
chemical_list: D010087:Oxides; D010455:Peptides; D006108:Graphite; D016547:Kinesins