title: Riluzole likely lacks antidepressant efficacy in ketamine non-responders.
authors.affiliation: National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA. Electronic address: mark.niciu@nih.gov.
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Niciu
authors.affiliation: National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA.
authors.forename: David A
authors.initials: DA
authors.lastname: Luckenbaugh
authors.affiliation: National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA.
authors.forename: Dawn F
authors.initials: DF
authors.lastname: Ionescu
authors.affiliation: National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA.
authors.forename: Erica M
authors.initials: EM
authors.lastname: Richards
authors.affiliation: National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Vande Voort
authors.affiliation: National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA.
authors.forename: Elizabeth D
authors.initials: ED
authors.lastname: Ballard
authors.affiliation: National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA.
authors.forename: Nancy E
authors.initials: NE
authors.lastname: Brutsche
authors.affiliation: National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA.
authors.forename: Maura L
authors.initials: ML
authors.lastname: Furey
authors.affiliation: National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA.
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Zarate
mesh_terms: D000328:Adult; D061218:Depressive Disorder, Treatment-Resistant / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D018691:Excitatory Amino Acid Antagonists / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007649:Ketamine / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D019782:Riluzole / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D018691:Excitatory Amino Acid Antagonists; D007649:Ketamine; D019782:Riluzole
keywords: Glutamate; Ketamine; Major depressive disorder; Riluzole; Treatment-resistant depression