title: Increased platelet count in severe peritoneal endometriosis.
abstract: OBJECTIVE
  Platelet count (PC) is higher in chronic inflammatory diseases. The aim of this study was to evaluate the PC in patients with severe pelvic endometriosis.
  
  
  METHODS
  Patients with advanced stage pelvic endometriosis were retrospectively evaluated in a tertiary center between January 2009 and December 2011. Patients with pelvic endometriosis were divided into two groups; advanced stage peritoneal endometriosis were classified as Group 1 (n = 28). Group 2 consisted of 29 patients which had ovarian endometrioma without clinically apparent peritoneal endometriosis foci. Group 3 included 51 women as control subjects. PC between the groups was tested by Student's t test. The mean values of three groups were analyzed by using one way ANOVA test followed post-hoc test Bonferroni.
  
  
  RESULTS
  PC in patients with pelvic endometriosis were found to be higher from the control group (290 +/- 67 10(9)/1; 264 +/- 63 10(9)/1, respectively; p = 0.038). Patients with peritoneal endometriosis (Group 1) had significantly higher PCs compared with the healthy controls (309 +/- 65 10(9)/1; 264 +/- 63 10(9)/1; respectively; p = 0.011).
  
  
  CONCLUSIONS
  Increased PC in advanced stage pelvic endometriosis may be a sign of increased systemic inflammation. The systemic inflammation may be more apparent in advanced stage peritoneal endometriosis.
authors.forename: M S
authors.initials: MS
authors.lastname: Evsen
authors.forename: H E
authors.initials: HE
authors.lastname: Soydinc
authors.forename: M E
authors.initials: ME
authors.lastname: Sak
authors.forename: A
authors.initials: A
authors.lastname: Ozler
authors.forename: A
authors.initials: A
authors.lastname: Turgut
authors.forename: Y
authors.initials: Y
authors.lastname: Celik
authors.forename: S Y
authors.initials: SY
authors.lastname: Tunc
authors.forename: T
authors.initials: T
authors.lastname: Gul
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004715:Endometriosis / Q000097:blood*; D005260:Female; D006801:Humans; D010049:Ovarian Diseases / Q000097:blood; D010532:Peritoneal Diseases / Q000097:blood*; D010976:Platelet Count; D055815:Young Adult