title: Aggressive natural killer-cell leukemia: classical presentation of a rare disease.
abstract: Aggressive natural killer-cell leukaemia is a rare aggressive form of natural killer-cell neoplasm. We report a case of a 40-year-old male who presented with jaundice, raised blood counts,generalised lymphadenopathy and hepatosplenomegaly. The diagnosis was established by flow cytometric analysis of bone marrow aspirate. The patient, however, succumbed to his illness within 2 weeks of starting chemotherapy. To the best of our knowledge, this is the third reported case from India.
authors.forename: Priya M
authors.initials: PM
authors.lastname: Jacob
authors.affiliation: Department of Pathology, Regional Cancer Centre, Trivandrum, Kerala, India.
authors.forename: Rekha A
authors.initials: RA
authors.lastname: Nair
authors.forename: Anila Kunjulekshmi Amma Raveendran
authors.initials: AK
authors.lastname: Nair
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001853:Bone Marrow / Q000473:pathology; D017809:Fatal Outcome; D005434:Flow Cytometry; D006801:Humans; D007194:India; D007694:Killer Cells, Natural; D007938:Leukemia / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology*; D008218:Lymphocytosis; D008297:Male; D008853:Microscopy; D035583:Rare Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents