title: Caveolin-1 in oral squamous cell carcinoma microenvironment: an overview.
abstract: Caveolin-1 plays an important role in the pathogenesis of oncogenic cell transformation, tumorigenesis, and metastasis. Increased expression of caveolin-1 in an array of tumors has confirmed its value in prognosis. It has been established that oxidative stress is the main cause for loss of stromal caveolin-1 via autophagy in the tumor microenvironment. In this overview, we attempt to abridge the relationship between caveolin-1 and oral squamous cell carcinoma, taking all the established theories into consideration.
authors.affiliation: Department of Oral Pathology & Microbiology, Institute of Dental Sciences, SOA University, Ghatikia, Sector 8, Bhubaneswar, 751003, India, drroutray.samapika@gmail.com.
authors.forename: Samapika
authors.initials: S
authors.lastname: Routray
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000378:metabolism*; D051242:Caveolin 1 / Q000378:metabolism*; D006801:Humans; D009062:Mouth Neoplasms / Q000378:metabolism*; D059016:Tumor Microenvironment / Q000502:physiology*
chemical_list: C495540:CAV1 protein, human; D051242:Caveolin 1