title: Incidence and trends of blastomycosis-associated hospitalizations in the United States.
abstract: We used the State Inpatient Databases from the United States Agency for Healthcare Research and Quality to provide state-specific age-adjusted blastomycosis-associated hospitalization incidence throughout the entire United States. Among the 46 states studied, states within the Mississippi and Ohio River valleys had the highest age-adjusted hospitalization incidence. Specifically, Wisconsin had the highest age-adjusted hospitalization incidence (2.9 hospitalizations per 100,000 person-years). Trends were studied in the five highest hospitalization incidence states. From 2000 to 2011, blastomycosis-associated hospitalizations increased significantly in Illinois and Kentucky with an average annual increase of 4.4% and 8.4%, respectively. Trends varied significantly by state. Overall, 64% of blastomycosis-associated hospitalizations were among men and the median age at hospitalization was 53 years. This analysis provides a complete epidemiologic description of blastomycosis-associated hospitalizations throughout the endemic area in the United States.
authors.affiliation: Epidemiology Unit, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America; Department of Epidemiology and Biostatistics, Milken Institute School of Public Health, The George Washington University, Washington, D.C., United States of America.
authors.forename: Amy E
authors.initials: AE
authors.lastname: Seitz
authors.affiliation: Department of Epidemiology and Biostatistics, Milken Institute School of Public Health, The George Washington University, Washington, D.C., United States of America.
authors.forename: Naji
authors.initials: N
authors.lastname: Younes
authors.affiliation: Healthcare Cost Utilization Project, United States Agency for Healthcare Research and Quality, Rockville, Maryland, United States of America.
authors.forename: Claudia A
authors.initials: CA
authors.lastname: Steiner
authors.affiliation: Epidemiology Unit, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
authors.forename: D Rebecca
authors.initials: DR
authors.lastname: Prevots
mesh_terms: D001759:Blastomycosis / Q000453:epidemiology* / Q000628:therapy; D005260:Female; D006760:Hospitalization / Q000639:trends; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D014481:United States / Q000453:epidemiology