title: Haematological and biochemical characteristics of the splenic effluent blood in schistosomal patients undergoing splenectomy.
abstract: OBJECTIVE
  To assess hematological and biochemical features of splenic effluent blood and their influence on the rise of hematological values after splenectomy.
  
  
  METHODS
  we studied 20 patients undergoing surgical treatment for schistosomatic portal hypertension. We collected blood samples for CBC, coagulation, bilirubin and albumin in the splenic vein (perioperative) and peripheral blood (immediately pre and postoperative periods).
  
  
  RESULTS
  the splenic blood showed higher values of red blood cells, hemoglobin, hematocrit, platelet count, total leukocytes, neutrophils, lymphocytes, monocytes, eosinophils and basophils, as well as reduction of laboratory coagulation parameters in relation to peripheral blood collected preoperatively. In the postoperative peripheral blood there was an increase in the overall leukocytes and in their neutrophil component, and decreased levels of basophils, eosinophils and lymphocytes. The other postoperative variables of complete blood count and coagulation tests were not different compared with the splenic blood. The albumin values were lower postoperatively when compared to preoperative and splenic blood. There were higher values of direct bilirubin in the postoperative period when compared with the preoperative and splenic blood. Postoperative indirect bilirubin was lower compared to its value in the splenic blood.
  
  
  CONCLUSIONS
  hematological and biochemical values of splenic effluent blood are higher than those found in peripheral blood in the presence of schistosomal splenomegaly. However, the splenic blood effluent is not sufficient to raise the blood levels found after splenectomy.
authors.affiliation: Department of Surgery, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
authors.forename: Andy
authors.initials: A
authors.lastname: Petroianu
authors.affiliation: Instituto Alfa de Gastroenterologia, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
authors.forename: Kelly Cristine de Lacerda Rodrigues
authors.initials: KC
authors.lastname: Buzatti
authors.affiliation: Department of Surgery, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
authors.forename: Vivian
authors.initials: V
authors.lastname: Resende
authors.affiliation: Santa Casa de Misericórdia de Belo Horizonte, MG, Brazil.
authors.forename: Kelly Renata
authors.initials: KR
authors.lastname: Sabino
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012552:Schistosomiasis / Q000097:blood* / Q000601:surgery*; D013154:Spleen / Q000098:blood supply*; D013156:Splenectomy; D013158:Splenic Diseases / Q000097:blood* / Q000469:parasitology / Q000601:surgery*; D055815:Young Adult