title: Metastatic hepatocellular carcinoma to parotid glands.
abstract: METHODS
  Male, 66.
  
  
  METHODS
  Hepatocellular carcinoma.
  
  
  METHODS
  Abdominal distension • painful right facial swelling • weight loss.
  
  
  METHODS
  -.
  
  
  METHODS
  -.
  
  
  METHODS
  -.
  
  
  OBJECTIVE
  Rare disease.
  
  
  BACKGROUND
  Hepatocellular carcinoma is a common cancer, but it rarely metastasizes to the salivary glands. A review of the literature revealed only 5 reported cases of hepatocellular carcinoma metastatic to parotid glands. We here report an additional case of this rare association.
  
  
  METHODS
  A 66-year-old male with a background of type 2 diabetes mellitus and post-alcoholic decompensated liver cirrhosis presented with a progressively enlarging painful right facial swelling for 2 months that was eventually found to be due to hepatocellular carcinoma metastatic to the right parotid gland. Fine needle aspiration from the right parotid showed sheets and single malignant cells that were interpreted as carcinoma not otherwise specific. However, biopsy showed metastatic hepatocellular carcinoma into the right parotid gland.
  
  
  CONCLUSIONS
  We report an additional case of the rare metastasis of hepatocellular carcinoma to the parotid glands. It should therefore be considered in a patient with decompensated liver cirrhosis presenting with a parotid swelling. Furthermore, the present case demonstrates the importance of the tissue biopsy for obtaining an accurate final diagnosis.
authors.affiliation: Department of Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.
authors.forename: Abdel-Naser
authors.initials: AN
authors.lastname: Elzouki
authors.affiliation: Department of Medicine, Hamad General Hospital, Hamad Medical Corporation, Dohaa, Qatar.
authors.forename: Hisham
authors.initials: H
authors.lastname: Elkhider
authors.affiliation: Department of Radiology, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.
authors.forename: Khalid
authors.initials: K
authors.lastname: Yacout
authors.affiliation: Department of Radiology, Hamad General Hospital, Hamad Medical Corporation, Dohaa, Qatar.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Al Muzrakchi
authors.affiliation: Department of Pathology, Hamad General Hospital, Hamad Medical Corporation, Dohaa, Qatar.
authors.forename: Shaikah
authors.initials: S
authors.lastname: Al-Thani
authors.affiliation: Department of Medicine, Hamad General Hospital, Hamad Medical Corporation, Dohaa, Qatar.
authors.forename: Omer
authors.initials: O
authors.lastname: Ismail
mesh_terms: D000368:Aged; D044963:Biopsy, Fine-Needle; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis / Q000556:secondary*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D009367:Neoplasm Staging; D010306:Parotid Gland / Q000473:pathology; D010307:Parotid Neoplasms / Q000175:diagnosis / Q000556:secondary*; D011859:Radiography