title: A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level.
abstract: Human immunodeficiency virus (HIV) infection is growing medical concern worldwide. There are many types of glomerulonephritis which are associated with HIV infection. We report a case of a 53-year-old Korean man with an HIV infection, who was developed nephritic range proteinuria and purpura with elevated IgA level rasing a possibility of Henoch-Schölein Purpura (H-S purpura). However, renal biopsy showed "lupus-like feature" glomerulonephritis without clinical or serologic evidence of systemic lupus erythematosus. Although baseline renal function was maintained without further need for maintenance dialysis following anti-retroviral therapy (ART) and steroid, patient died from uncontrolled gastrointestinal bleeding.
authors.affiliation: Department of Internal Medicine, Division of Nephrology, National Medical Center Seoul, Korea.
authors.forename: Jihyun
authors.initials: J
authors.lastname: Yang
authors.affiliation: Department of Internal Medicine, Division of Nephrology, National Medical Center Seoul, Korea.
authors.forename: Min Young
authors.initials: MY
authors.lastname: Seo
authors.affiliation: Department of Internal Medicine, Division of Nephrology, National Medical Center Seoul, Korea.
authors.forename: Ki Tae
authors.initials: KT
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Division of Nephrology, National Medical Center Seoul, Korea.
authors.forename: Jun Yong
authors.initials: JY
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Division of Nephrology, National Medical Center Seoul, Korea.
authors.forename: Sun-Chul
authors.initials: SC
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Division of Nephrology, National Medical Center Seoul, Korea.
authors.forename: Myung-Gyu
authors.initials: MG
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Division of Nephrology, National Medical Center Seoul, Korea.
authors.forename: Sang-Kyung
authors.initials: SK
authors.lastname: Jo
authors.affiliation: Department of Internal Medicine, Division of Nephrology, National Medical Center Seoul, Korea.
authors.forename: Won-Yong
authors.initials: WY
authors.lastname: Cho
authors.affiliation: Department of Internal Medicine, Division of Nephrology, National Medical Center Seoul, Korea.
authors.forename: Hyoung-Kyu
authors.initials: HK
authors.lastname: Kim
authors.affiliation: Department of Pathology, Korea University Anam Hospital, National Medical Center Seoul, Korea.
authors.forename: Nam Hee
authors.initials: NH
authors.lastname: Won
authors.affiliation: Department of Internal Medicine, Division of Nephrology, National Medical Center Seoul, Korea.
authors.forename: Ran-Hui
authors.initials: RH
authors.lastname: Cha
authors.affiliation: Department of Internal Medicine, Division of Nephrology, National Medical Center Seoul, Korea.
authors.forename: Eunjung
authors.initials: E
authors.lastname: Cho
mesh_terms: D005921:Glomerulonephritis / Q000473:pathology* / Q000503:physiopathology / Q000821:virology; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007105:Immune Complex Diseases / Q000473:pathology* / Q000503:physiopathology / Q000821:virology; D007070:Immunoglobulin A / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011507:Proteinuria / Q000503:physiopathology / Q000821:virology; D011693:Purpura / Q000473:pathology / Q000503:physiopathology / Q000821:virology
chemical_list: D007070:Immunoglobulin A
keywords: HIV-associated nephropathy; Human immunodeficiency virus; glomerulonephritis; lupus nephritis; renal biopsy