title: Executive function late effects in survivors of pediatric brain tumors and acute lymphoblastic leukemia.
abstract: BACKGROUND
  Survivors of pediatric brain tumors (BT) and acute lymphoblastic leukemia (ALL) are at risk for neurocognitive late effects related to executive function.
  
  
  METHODS
  Survivors of BT (48) and ALL (50) completed neurocognitive assessment. Executive function was compared to estimated IQ and population norms by diagnostic group.
  
  
  RESULTS
  Both BT and ALL demonstrated relative executive function weaknesses. As a group, BT survivors demonstrated weaker executive functioning than expected for age. Those BT survivors with deficits exhibited a profile suggestive of global executive dysfunction, while affected ALL survivors tended to demonstrate specific rapid naming deficits.
  
  
  CONCLUSIONS
  Findings suggest that pediatric BT and ALL survivors may exhibit different profiles of executive function late effects, which may necessitate distinct intervention plans.
authors.affiliation: a Department of Pediatrics, Section of Psychology , Baylor College of Medicine , Houston , TX , USA.
authors.forename: Amanda L
authors.initials: AL
authors.lastname: Winter
authors.forename: Heather M
authors.initials: HM
authors.lastname: Conklin
authors.forename: Vida L
authors.initials: VL
authors.lastname: Tyc
authors.forename: Heather
authors.initials: H
authors.lastname: Stancel
authors.forename: Pamela S
authors.initials: PS
authors.lastname: Hinds
authors.forename: Melissa M
authors.initials: MM
authors.lastname: Hudson
authors.forename: Lisa S
authors.initials: LS
authors.lastname: Kahalley
mesh_terms: D000293:Adolescent; D001932:Brain Neoplasms / Q000150:complications*; D002648:Child; D003072:Cognition Disorders / Q000209:etiology*; D056344:Executive Function / Q000502:physiology*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009483:Neuropsychological Tests; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D017741:Survivors / Q000523:psychology*
keywords: Brain tumor; Executive function; Late effects; Leukemia; Pediatric