title: Metabolomic (anthropometric and biochemical) indexes and metabolic syndrome in adolescents and young adults with intellectual disabilities.
abstract: The aim of the present study was to describe the use of combination of international standardized anthropometric parameters, along with biochemical parameters (metabolomic indexes) to identify metabolic syndrome (MetS), in persons with intellectual disabilities. We conducted a cross-sectional study of 42 adolescents and young adults with intellectual disabilities (aged 13-30years) who attend special schools in Ciudad Juárez, Chihuahua, México. The study included anthropometric (using the International Society for the Advancement of Kineanthropometry recommendations) and biochemical measures, and their combinations as metabolomic-indexes, that can significantly predict MetS occurrence in this vulnerable population. Waist circumference (WC) and relaxed arm circumference, both adjusted for height, have the highest correlation with MetS (R2=0.23-0.47, p<0.01). Besides body mass index (BMI) and WC we propose other indicators such as, skinfolds, hip circumference and relaxed arm circumference, all of them adjusted by height in order to better define the presence of MetS in persons with intellectual disabilities.
authors.affiliation: Department of Health Sciences, Autonomous University of Ciudad Juarez, Anillo Envolvente del PRONAF y Estocolmo s/n, Ciudad Juárez 32310, Chihuahua, Mexico. Electronic address: aramos@uacj.mx.
authors.forename: Arnulfo
authors.initials: A
authors.lastname: Ramos-Jiménez
authors.affiliation: School of Sciences of Physical Culture, Autonomous University of Chihuahua, Ciudad Juárez, Chihuahua, Mexico. Electronic address: rphernant@yahoo.com.
authors.forename: Rosa Patricia
authors.initials: RP
authors.lastname: Hernández-Torres
authors.affiliation: Department of Health Sciences, Autonomous University of Ciudad Juarez, Anillo Envolvente del PRONAF y Estocolmo s/n, Ciudad Juárez 32310, Chihuahua, Mexico. Electronic address: awall@uacj.mx.
authors.forename: Abraham
authors.initials: A
authors.lastname: Wall-Medrano
authors.affiliation: Department of Health Sciences, Autonomous University of Ciudad Juarez, Anillo Envolvente del PRONAF y Estocolmo s/n, Ciudad Juárez 32310, Chihuahua, Mexico; Biomedicine Unit, School of Higher Studies Iztacala, National Autonomous University of México, Tlalnepantla, Mexico. Electronic address: villalobos@campus.iztacala.unam.mx.
authors.forename: Rafael
authors.initials: R
authors.lastname: Villalobos-Molina
mesh_terms: D000293:Adolescent; D000328:Adult; D000886:Anthropometry; D001132:Arm / Q000033:anatomy & histology; D001786:Blood Glucose; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D003430:Cross-Sectional Studies; D005260:Female; D006615:Hip; D006801:Humans; D008607:Intellectual Disability / Q000150:complications*; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D009929:Organ Size; D012885:Skinfold Thickness; D014280:Triglycerides / Q000097:blood; D055105:Waist Circumference; D049629:Waist-Hip Ratio; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D008076:Cholesterol, HDL; D014280:Triglycerides; D002784:Cholesterol
keywords: Arm circumference; Cardiovascular risk; Metabolic syndrome index; Obesity; Skinfolds