title: [Bile duct lesions repaired with peritoneal tube grafts].
abstract: BACKGROUND
  A significant number of people suffer iatrogenic bile duct injury during laparoscopic cholescystectomy. Biliary-digestive bypass may be complicated by stenosis and biliary sepsis, affecting both quality of life and life expectancy. To avoid bypass synthetic grafts have been used, which are expensive.
  
  
  OBJECTIVE
  Evaluating autologous implantation of peritoneus as alternative of bile duct repair.
  
  
  METHODS
  Under general anesthesia, ten New Zealand adult rabbits were operated, common bile duct approached and sectioned underneath the cystic duct followed by a liver biopsy. An autologous graft was built of peritoneum and graft-bile duct proximal and distal end-to-end anastomosis done. Animals were followed-up by weekly bilirrubin and transferases. Rabbits were scheduled euthanized and a liver biopsy done for histological examinations.
  
  
  RESULTS
  Autologous graft was easy to create and all rabbits survived. They did not develop jaundice or alterations in their normal habits. At necropsy, autologous grafts were removed and no signs of occlusion were noticed. Moderate short-term liver damage was observed but long-term damage was negligible. Bileoma and pyogenic liver abscess were observed in two animals, respectively.
  
  
  CONCLUSIONS
  Our results favourably match well-known procedures used for bile duct repair, especially in cases of severe injury (Bismuth-Strasberg E1-3): it seems less complicated than biliary-digestive bypass, not as expensive as synthetic grafts, and much easier to build than human amnion graft.
  
  
  CONCLUSIONS
  Interposing an autologous graft of peritoneum is an easy-to-create surgical procedure and circumferential bile duct injuries were adequately repaired.
authors.affiliation: Departamento de Cirugía, Hospital Regional de Alta Especialidad de Veracruz, Secretaría de Salud, Veracruz, Mexico.
authors.forename: Ileana
authors.initials: I
authors.lastname: Lorenzana-Bautista
authors.affiliation: Departamento de Cirugía, Hospital Regional de Alta Especialidad de Veracruz, Secretaría de Salud, Veracruz, Mexico.
authors.forename: Aníbal
authors.initials: A
authors.lastname: Flores-Plascencia
authors.affiliation: Departamento de Enseñanza, Hospital Regional de Alta Especialidad de Veracruz, Secretaría de Salud, Veracruz, Mexico.
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Barrios-Pineda
authors.affiliation: Departamento de Patología, Hospital Regional de Alta Especialidad de Veracruz, Secretaría de Salud, Veracruz, Mexico.
authors.forename: Georgia
authors.initials: G
authors.lastname: Alderete-Vázquez
authors.affiliation: Departamento de Investigación, Escuela de Medicina, Universidad Cristóbal Colón, Veracruz, Mexico. easanchezv@gmail.com.
authors.forename: Enrique Alejandro
authors.initials: EA
authors.lastname: Sánchez-Valdivieso
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000714:Anastomosis, Surgical; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000097:blood; D001705:Bioprosthesis; D003135:Common Bile Duct / Q000293:injuries / Q000601:surgery*; D008099:Liver / Q000473:pathology; D008100:Liver Abscess / Q000097:blood / Q000209:etiology / Q000473:pathology; D010537:Peritoneum; D011183:Postoperative Complications / Q000097:blood / Q000473:pathology; D011817:Rabbits; D014182:Transplantation, Autologous
chemical_list: D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D001663:Bilirubin
keywords: Common bile duct injury; animal model; autologous graft; lesión, colédoco; modelo animal