title: Melatonin improve the sperm quality in forced swimming test induced oxidative stress in nandrolone treated Wistar rats.
abstract: This study investigates the effects of melatonin on the sperm quality and testis weight after the combination of swimming exercise and nandrolone decanoate (DECA). Two groups of male Wistar rats were treated for eight weeks as follows; group A consist of CO (control), Sham, N (DECA), S (swimming) and NS (DECA plus swimming); and group B: Sham M (sham melatonin), M (melatonin), MN (melatonin plus DECA), MS (melatonin plus swimming), MNS (melatonin, DECA plus swimming). The motility of sperm was significantly improved in melatonin groups in comparison to N, S and NS groups (P≤0.05).  The left testes weight was decreased in N, NS and MNS groups, and the right testes weight was decreased in N,S,NS, MS and MNS groups in compare with the control group. This study concluded that melatonin probably could improve the sperm motility and sex organs weight after the combination of DECA and exercise.
authors.affiliation: Department of Anatomy, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. aeedshus@zums.ac.ir.
authors.forename: Bagher
authors.initials: B
authors.lastname: Minaii
authors.affiliation: Department of Anatomy, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.AND Department of Anatomy, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran. aeedshus@zums.ac.ir.
authors.forename: Ardeshir
authors.initials: A
authors.lastname: Moayeri
authors.affiliation: Department of Anatomy, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran. aeedshus@zums.ac.ir.
authors.forename: Saeed
authors.initials: S
authors.lastname: Shokri
authors.affiliation: Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran. saeedshus@zums.ac.ir.
authors.forename: Mehryar
authors.initials: M
authors.lastname: Habibi Roudkenar
authors.affiliation: Department of Clinical Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. saeedshus@zums.ac.ir.
authors.forename: Taghi
authors.initials: T
authors.lastname: Golmohammadi
authors.affiliation: Department of Anatomy, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. saeedshus@zums.ac.ir.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Malek
authors.affiliation: Department of Anatomy, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. barbarestani@sina.tums.ac.ir.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Barbarestani
mesh_terms: D045930:Anabolic Agents / Q000494:pharmacology; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D004195:Disease Models, Animal; D006801:Humans; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D009277:Nandrolone / Q000031:analogs & derivatives* / Q000494:pharmacology; D000077603:Nandrolone Decanoate; D018384:Oxidative Stress / Q000187:drug effects*; D010805:Physical Conditioning, Animal; D051381:Rats; D017208:Rats, Wistar; D055101:Semen Analysis; D013094:Spermatozoa / Q000187:drug effects / Q000378:metabolism*; D013550:Swimming
chemical_list: D045930:Anabolic Agents; D000975:Antioxidants; D009277:Nandrolone; D000077603:Nandrolone Decanoate; D008550:Melatonin