title: Substrate utilization during and after high intensity exercise in healthy lean and obese men.
abstract: OBJECTIVE
  To compare lipid and carbohydrate use during and after a high-intensity endurance exercise bout between lean and obese subjects.
  
  
  METHODS
  Lean and obese healthy male subjects with energetic physical activity and stable body weight were recruited to participate in the present study. The respiratory exchange ratio (RER), lipid and carbohydrate oxidation, and lipid and carbohydrate energy expenditure during resting condition, high-intensity exercise and 180 min after exercise were determined by indirect calorimetry
  
  
  RESULTS
  Ten lean and ten obese healthy male subjects, aged 26+/-4 years, completed a 300-kcal high-intensity exercise session. Resting energy expenditure and lipid energy expenditure in the obese group were significantly higher than those of the lean group. The RER, lipid oxidation, and carbohydrate oxidation were not significantly different between groups throughout the exercise period. The total energy expenditure and total lipid and carbohydrate energy expenditure were also not significantly different between lean and obese groups. During the 180-minute post exercise period, both lean and obese subjects showed a declination in RER and carbohydrate oxidation and an increase in lipid oxidation.
  
  
  CONCLUSIONS
  Substrate use during and after high-intensity exercise between healthy lean and obese subjects was not significantly different. Both groups used carbohydrates and lipids as the main substrate sources during and after high-intensity exercise, respectively.
authors.forename: Anoma
authors.initials: A
authors.lastname: Santiworakul
authors.forename: Benjamas
authors.initials: B
authors.lastname: Chuaychoo
authors.forename: Wantanee
authors.initials: W
authors.lastname: Kriengsinyos
authors.forename: Vitoon
authors.initials: V
authors.lastname: Saengsirisuwan
authors.forename: Wattana
authors.initials: W
authors.lastname: Jalayondeja
mesh_terms: D000328:Adult; D001835:Body Weight / Q000502:physiology*; D002153:Calorimetry, Indirect; D004734:Energy Metabolism / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D006801:Humans; D008297:Male; D009765:Obesity / Q000503:physiopathology*; D055815:Young Adult