title: New approach for the step by step control of magnetic nanostructure functionalization.
abstract: This paper describes the synthesis, functionalization, and multitechnique analysis of magnetic nanoparticles. The synthetic method involves the covering of a magnetite nucleus by a silica layer and the further functionalization with different fluorophores via a cross-linker molecule. All synthetic intermediates were analyzed by fluorescence spectroscopy and AC magnetic susceptibility. For one of the considered molecules, a further investigation with STEM, EDXS, and DLS has been conducted in order to validate the proposed magnetic results. The comparison between the two techniques is used to ensure a complete characterization of the product confirming the success of the synthesis. By comparing the magnetic and the fluorescence measurements, we also demonstrate the effectiveness of AC susceptibility as a robust and versatile technique to follow the synthesis of complex magnetic nanostructures regardless of the nature of the functionalization.
authors.affiliation: Department of Chemistry and Industrial Chemistry, University of Genoa , Via Dodecaneso 31, 16146 Genoa, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Riani
authors.forename: M A
authors.initials: MA
authors.lastname: Lucchini
authors.forename: S
authors.initials: S
authors.lastname: Thea
authors.forename: M
authors.initials: M
authors.lastname: Alloisio
authors.forename: G
authors.initials: G
authors.lastname: Bertoni
authors.forename: F
authors.initials: F
authors.lastname: Canepa
mesh_terms: D008280:Magnetics; D008855:Microscopy, Electron, Scanning; D049329:Nanostructures; D066244:Proton Magnetic Resonance Spectroscopy; D013050:Spectrometry, Fluorescence