title: [A case of post-operative recurrence of pancreatic cancer in the residual pancreas treated by resection of the residual pancreas following radiological complete response achieved with second-line FOLFIRINOX].
abstract: A 65-year-old woman with carcinoma of the pancreatic body underwent Whipple's operation. After surgery, adjuvant chemotherapy with gemcitabine alone, and S-1 combined with gemcitabine was conducted. But one year later, a recurrent tumor was detected in the pancreatic tail. We administered FOLFIRINOX treatment for the recurrent tumor. After 6 courses, FOLFIRINOX treatment resulted in a partial response, and after 9 courses, a radiological complete response was achieved. We could then perform total pancreatotectomy and resection of the metastatic liver tumor. FOLFIRINOX as a second-line treat- ment was effective and safe in this case. In cases of gemcitabine and/or S-1 failure, FOLFIRINOX treatment should be considered.
authors.affiliation: Division of Clinical Oncology, Yokohama City University Hospital.
authors.forename: Noritoshi
authors.initials: N
authors.lastname: Kobayashi
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shimamura
authors.forename: Motohiko
authors.initials: M
authors.lastname: Tokuhisa
authors.forename: Ayumu
authors.initials: A
authors.lastname: Goto
authors.forename: Ryutaro
authors.initials: R
authors.lastname: Mori
authors.forename: Ryusei
authors.initials: R
authors.lastname: Matsuyama
authors.forename: Koichi
authors.initials: K
authors.lastname: Taniguchi
authors.forename: Kuniya
authors.initials: K
authors.lastname: Tanaka
authors.forename: Hirotoshi
authors.initials: H
authors.lastname: Akiyama
authors.forename: Itaru
authors.initials: I
authors.lastname: Endo
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Ichikawa
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D010190:Pancreatic Neoplasms / Q000188:drug therapy* / Q000601:surgery; D016577:Pancreaticoduodenectomy; D012008:Recurrence; D014057:Tomography, X-Ray Computed