title: 1,3-Halogen migration as an entry to aryl coppers from an unintuitive starting material.
abstract: A copper(I) catalyzed 1,3-halogen migration/borylation migrates a bromine from an sp(2) carbon to a benzylic carbon with concomitant borylation of the aryl-bromine bond. This transformation proceeds via an aryl copper intermediate which can be accessed independently and then trapped with electrophiles. As such, copper-catalyzed 1,3-halogen migration provides unique and mild access to an aryl copper species that allows for rapid aromatic functionalization from an unconventional starting material.
authors.affiliation: Department of Chemistry, University of Wisconsin, 1101 University Ave., Madison, Wisconsin 53706, USA. schomakerj@chem.wisc.edu.
authors.forename: R J
authors.initials: RJ
authors.lastname: Van Hoveln
authors.forename: S C
authors.initials: SC
authors.lastname: Schmid
authors.forename: J M
authors.initials: JM
authors.lastname: Schomaker
mesh_terms: D001554:Benzene / Q000737:chemistry*; D001895:Boron / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006219:Halogens / Q000737:chemistry*
chemical_list: D006219:Halogens; D003300:Copper; D001554:Benzene; D001895:Boron