title: Pulmonary embolism in burns, is there an evidence based prophylactic recommendation? Case report and review of literature.
abstract: Burn patients exhibit an acquired hypercoagulable state with increased risk of venous thromboembolism. Currently, no randomized control study assessing the efficacy of chemical venous thromboembolism (VTE) prophylaxis in burn patients has been performed. We present a case of a morbidly (body mass index>54kg/m(2)) obese patient with 18% total body surface area (TBSA) burn who developed a VTE and a non-fatal submassive pulmonary embolus (PE). We will be reviewing the current consensus of venous thrombosis prophylaxis in burn patients and briefly discuss the treatment of PE in this population.
authors.affiliation: Johns Hopkins University School of Medicine, Johns Hopkins Burn Center, Baltimore, MD 21224, United States.
authors.forename: Raul
authors.initials: R
authors.lastname: Sebastian
authors.affiliation: Medstar Union Memorial Hospital, Baltimore, MD 21218, United States.
authors.forename: Omar
authors.initials: O
authors.lastname: Ghanem
authors.affiliation: Johns Hopkins University School of Medicine, Johns Hopkins Burn Center, Baltimore, MD 21224, United States.
authors.forename: Frank
authors.initials: F
authors.lastname: DiRoma
authors.affiliation: Johns Hopkins University School of Medicine, Johns Hopkins Burn Center, Baltimore, MD 21224, United States.
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Milner
authors.affiliation: Johns Hopkins University School of Medicine, Johns Hopkins Burn Center, Baltimore, MD 21224, United States. Electronic address: lprice13@jhmi.edu.
authors.forename: Leigh A
authors.initials: LA
authors.lastname: Price
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use*; D002056:Burns / Q000150:complications*; D017984:Enoxaparin / Q000627:therapeutic use*; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D009765:Obesity / Q000150:complications; D011655:Pulmonary Embolism / Q000150:complications / Q000517:prevention & control*; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants; D017984:Enoxaparin
keywords: Acquired hypercoagulopathy; Blood clot; Burn wounds; Deep venous thrombosis; Pulmonary embolism; Venous thromboembolism