title: A Beautician's Dystonia: Long-Lasting Effect of Botulinum Toxin.
abstract: Treatment options for dystonia are not curative but symptomatic; the treatment of choice for focal dystonias is repeated botulinum toxin injections. Here, we present the case of a 46-year-old beautician with focal dystonia in her left hand that affected her ability to work. Pharmacological treatment with clonazepam and gabapentin failed to resolve her symptoms and was discontinued due to side effects (sleepiness, gastrointestinal disorders). Intramuscular injection of botulinum toxin (incobotulinumtoxinA, Xeomin) into the extensor digitorum communis (35 U), flexor carpi radialis (35 U), and flexor digitorum superficialis (30 U) muscles resulted in complete resolution of symptoms at clinical assessments at 1, 3, 6, and 10 months after the injections, confirmed by the results of surface electromyography 10 months after treatment. The patient was able to work again 1 month after treatment. No reinjection has been necessary at the last evaluation (12 months after treatment). In conclusion, botulinum toxin is an effective treatment for focal dystonia that can have long-lasting effects and can improve patients' ability to work and quality of life.
authors.affiliation: Unit of Neurorehabilitation, University Hospital of Pisa, 56124 Pisa, Italy.
authors.forename: Siria
authors.initials: S
authors.lastname: Di Martino
authors.affiliation: Unit of Neurorehabilitation, University Hospital of Pisa, 56124 Pisa, Italy.
authors.forename: Stefania
authors.initials: S
authors.lastname: Dalise
authors.affiliation: Unit of Neurorehabilitation, University Hospital of Pisa, 56124 Pisa, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Lamola
authors.affiliation: Unit of Neurorehabilitation, University Hospital of Pisa, 56124 Pisa, Italy.
authors.forename: Martina
authors.initials: M
authors.lastname: Venturi
authors.affiliation: Unit of Neurorehabilitation, University Hospital of Pisa, 56124 Pisa, Italy.
authors.forename: Bruno
authors.initials: B
authors.lastname: Rossi
authors.affiliation: Unit of Neurorehabilitation, University Hospital of Pisa, 56124 Pisa, Italy.
authors.forename: Carmelo
authors.initials: C
authors.lastname: Chisari