title: Corneal collagen crosslinking failure in a patient with floppy eyelid syndrome.
abstract: A 30-year-old man with bilateral floppy eyelid syndrome (more prominent in the left eye) and progressive keratoconus had corneal collagen crosslinking (CXL) in both eyes. No intraoperative or early postoperative complications were found. Topographic examination after CXL revealed a continuous increase in the keratometric values in the left eye in which the floppy eyelid syndrome was more prominent, indicating keratoconus progression (CXL failure). The fellow eye with the less prominent floppy eyelid syndrome remained stable during the follow-up period. Floppy eyelid syndrome could be a risk factor for CXL failure.
  
  
  BACKGROUND
  No author has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: From the Vardinoyiannion Eye Institute of Crete (Kymionis, Grentzelos, Liakopoulos, Kontadakis, Stojanovic), Faculty of Medicine, University of Crete, Heraklion, Crete, Greece, and the Bascom Palmer Eye Institute (Kymionis), Miller School of Medicine, University of Miami, Miami, Florida, USA. Electronic address: kymionis@med.uoc.gr.
authors.forename: George D
authors.initials: GD
authors.lastname: Kymionis
authors.affiliation: From the Vardinoyiannion Eye Institute of Crete (Kymionis, Grentzelos, Liakopoulos, Kontadakis, Stojanovic), Faculty of Medicine, University of Crete, Heraklion, Crete, Greece, and the Bascom Palmer Eye Institute (Kymionis), Miller School of Medicine, University of Miami, Miami, Florida, USA.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Grentzelos
authors.affiliation: From the Vardinoyiannion Eye Institute of Crete (Kymionis, Grentzelos, Liakopoulos, Kontadakis, Stojanovic), Faculty of Medicine, University of Crete, Heraklion, Crete, Greece, and the Bascom Palmer Eye Institute (Kymionis), Miller School of Medicine, University of Miami, Miami, Florida, USA.
authors.forename: Dimitrios A
authors.initials: DA
authors.lastname: Liakopoulos
authors.affiliation: From the Vardinoyiannion Eye Institute of Crete (Kymionis, Grentzelos, Liakopoulos, Kontadakis, Stojanovic), Faculty of Medicine, University of Crete, Heraklion, Crete, Greece, and the Bascom Palmer Eye Institute (Kymionis), Miller School of Medicine, University of Miami, Miami, Florida, USA.
authors.forename: George A
authors.initials: GA
authors.lastname: Kontadakis
authors.affiliation: From the Vardinoyiannion Eye Institute of Crete (Kymionis, Grentzelos, Liakopoulos, Kontadakis, Stojanovic), Faculty of Medicine, University of Crete, Heraklion, Crete, Greece, and the Bascom Palmer Eye Institute (Kymionis), Miller School of Medicine, University of Miami, Miami, Florida, USA.
authors.forename: Nela
authors.initials: N
authors.lastname: Stojanovic
mesh_terms: D000328:Adult; D003094:Collagen / Q000378:metabolism*; D003319:Corneal Stroma / Q000378:metabolism*; D019781:Corneal Topography; D003432:Cross-Linking Reagents; D005141:Eyelid Diseases / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D007640:Keratoconus / Q000150:complications* / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use; D012256:Riboflavin / Q000627:therapeutic use; D017211:Treatment Failure; D014466:Ultraviolet Rays
chemical_list: D003432:Cross-Linking Reagents; D017319:Photosensitizing Agents; D003094:Collagen; D012256:Riboflavin