title: Organocatalytic amination of alkyl ethers via n-Bu4NI/t-BuOOH-mediated intermolecular oxidative C(sp(3))-N bond formation: novel synthesis of hemiaminal ethers.
abstract: A novel method for constructing the hemiaminal ether framework under metal-free conditions has been developed. It involves direct organocatalytic amination of alkyl ethers through intermolecular oxidative C(sp(3))-N bond formation, with t-BuOOH being the oxidant and n-Bu4NI as the catalyst.
authors.affiliation: School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China. duyunfeier@tju.edu.cn.
authors.forename: Longyang
authors.initials: L
authors.lastname: Dian
authors.forename: Sisi
authors.initials: S
authors.lastname: Wang
authors.forename: Daisy
authors.initials: D
authors.lastname: Zhang-Negrerie
authors.forename: Yunfei
authors.initials: Y
authors.lastname: Du
authors.forename: Kang
authors.initials: K
authors.lastname: Zhao
mesh_terms: D000586:Amination; D000588:Amines / Q000737:chemistry; D002384:Catalysis; D004987:Ethers / Q000138:chemical synthesis* / Q000737:chemistry; D016877:Oxidants / Q000737:chemistry*; D010084:Oxidation-Reduction; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D020122:tert-Butylhydroperoxide / Q000737:chemistry*
chemical_list: D000588:Amines; D004987:Ethers; D016877:Oxidants; D000644:Quaternary Ammonium Compounds; D020122:tert-Butylhydroperoxide; C009405:tetrabutylammonium