title: Enzymatic synthesis of fatty hydroxamic acid derivatives based on palm kernel oil.
abstract: Fatty hydroxamic acid derivatives were synthesized using Lipozyme TL IM catalyst at biphasic medium as the palm kernel oil was dissolved in hexane and hydroxylamine derivatives were dissolved in water: (1) N-methyl fatty hydroxamic acids (MFHAs); (2) N-isopropyl fatty hydroxamic acids (IPFHAs) and (3) N-benzyl fatty hydroxamic acids (BFHAs) were synthesized by reaction of palm kernel oil and N-methyl hydroxylamine (N-MHA), N-isopropyl hydroxylamine (N-IPHA) and N-benzyl hydroxylamine (N-BHA), respectively. Finally, after separation the products were characterized by color testing, elemental analysis, FT-IR and 1H-NMR spectroscopy. For achieving the highest conversion percentage of product the optimum molar ratio of reactants was obtained by changing the ratio of reactants while other reaction parameters were kept constant. For synthesis of MFHAs the optimum mol ratio of N-MHA/palm kernel oil = 6/1 and the highest conversion was 77.8%, for synthesis of IPFHAs the optimum mol ratio of N-IPHA/palm kernel oil = 7/1 and the highest conversion was 65.4% and for synthesis of BFHAs the optimum mol ratio of N-BHA/palm kernel oil = 7/1 and the highest conversion was 61.7%.
authors.affiliation: Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, UPM Serdang, Selangor 43400, Malaysia. kamran.jahangirian@gmail.com.
authors.forename: Hossein
authors.initials: H
authors.lastname: Jahangirian
authors.affiliation: Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, UPM Serdang, Selangor 43400, Malaysia. mdjelas@science.upm.edu.my.
authors.forename: Md Jelas
authors.initials: MJ
authors.lastname: Haron
authors.affiliation: Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, UPM Serdang, Selangor 43400, Malaysia.
authors.forename: Nor Azah
authors.initials: NA
authors.lastname: Yusof
authors.affiliation: Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, UPM Serdang, Selangor 43400, Malaysia.
authors.forename: Sidik
authors.initials: S
authors.lastname: Silong
authors.affiliation: Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, UPM Serdang, Selangor 43400, Malaysia.
authors.forename: Anuar
authors.initials: A
authors.lastname: Kassim
authors.affiliation: School of Chemical Sciences and food Technology, Faculty of science and Technology, Universiti Kebangsaan Malaysia, UKM Bangi, Selangor 43600, Malaysia.
authors.forename: Roshanak
authors.initials: R
authors.lastname: Rafiee-Moghaddam
authors.affiliation: Department of Chemical and Environmental Engineering, Faculty of Engineering, Universiti Putra Malaysia, UPM Serdang, Selangor 43400, Malaysia.
authors.forename: Mazyar
authors.initials: M
authors.lastname: Peyda
authors.affiliation: Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, UPM Serdang, Selangor 43400, Malaysia.
authors.forename: Yadollah
authors.initials: Y
authors.lastname: Gharayebi
mesh_terms: D004602:Elements; D005227:Fatty Acids / Q000138:chemical synthesis*; D006877:Hydroxamic Acids / Q000138:chemical synthesis*; D008049:Lipase / Q000378:metabolism*; D000073878:Palm Oil; D010938:Plant Oils / Q000737:chemistry*; D066244:Proton Magnetic Resonance Spectroscopy; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D004602:Elements; D005227:Fatty Acids; D006877:Hydroxamic Acids; D010938:Plant Oils; D000073878:Palm Oil; C093666:Lipozyme; D008049:Lipase