title: Changes in sleep characteristics and airway obstruction in OSAHS patients with multi-level obstruction following simple UPPP, UPPP-GA, or UPPP-TBA: a prospective, single-center, parallel group study.
abstract: OBJECTIVE
  To investigate changes in S3 sleep and the apnea hypopnea index (AHI), SpO2 desaturation and CT90, and to determine changes in the degree of airway collapse and in the cross-sectional area of the retropalatal and lingual region in obstructive sleep apnea hypopnea syndrome patients.
  
  
  METHODS
  All subjects underwent overnight polysomnography and were evaluated using Müller's test and magnetic resonance imaging at baseline, 3, and 12 months following surgery.
  
  
  RESULTS
  The mean S3 scores in patients receiving uvulopalatopharyngoplasty combined with genioglossus advancement (UPPP-GA) or UPPP combined with tongue base advancement using the Repose™ system (UPPP-TBA) noticeably increased. Marked improvement was seen in the mean AHI, LSO2, and CT90 scores 3 and 12 months following surgery compared to baseline. Airway collapsed by 25-50% in the greatest proportion undergoing surgery at the tongue base.
  
  
  CONCLUSIONS
  UPPP-GA and UPPP-TBA more effectively improve S3 sleep, and mean AHI, LSO2, and CT90 scores. In addition, they effectively alleviate airway obstruction by improving the cross-sectional area of these regions.
authors.affiliation: Department of Otolaryngology - Head and Neck Surgery, Changhai Hospital, The Second Military Medical University, Shanghai, China.
authors.forename: Shicai
authors.initials: S
authors.lastname: Chen
authors.forename: Song
authors.initials: S
authors.lastname: Shi
authors.forename: Yanghui
authors.initials: Y
authors.lastname: Xia
authors.forename: Fei
authors.initials: F
authors.lastname: Liu
authors.forename: Donghui
authors.initials: D
authors.lastname: Chen
authors.forename: Minhui
authors.initials: M
authors.lastname: Zhu
authors.forename: Meng
authors.initials: M
authors.lastname: Li
authors.forename: Hongliang
authors.initials: H
authors.lastname: Zheng
mesh_terms: D000328:Adult; D000402:Airway Obstruction / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013517:Otorhinolaryngologic Surgical Procedures / Q000379:methods*; D010159:Palate / Q000601:surgery*; D010614:Pharynx / Q000601:surgery*; D017286:Polysomnography; D011446:Prospective Studies; D012890:Sleep / Q000502:physiology*; D020181:Sleep Apnea, Obstructive / Q000503:physiopathology / Q000601:surgery*