title: CDC Kerala 3: At-risk baby clinic service using different screening tools--outcome at 12 months using Developmental Assessment Scale for Indian Infants.
abstract: OBJECTIVE
  To describe CDC Kerala experience of establishing an at-risk baby clinic and the comparison of different developmental screening tools at 12 mo against the gold standard Developmental Assessment Scale for Indian Infants (DASII).
  
  
  METHODS
  At risk baby clinic of CDC, Kerala was established as a facility for follow up of NICU graduates from Sree Avittam Thirunal Hospital at 2, 4, 6, 8 and 12 mo corrected age and during each visit the mother is taught the CDC model early stimulation by developmental therapists and encouraged to continue to do the same at home. At 12 mo, assessment results of four simple developmental tools were compared with the gold standard DASII administered by a senior developmental therapist.
  
  
  RESULTS
  Out of a total of 800 babies, outcome measurements at 12 mo were available for 604 infants. The prevalence of developmental delay using the screening tools, CDC grading for standing, Amiel Tison angles and DDST II (Denver II) gross motor were 24.8, 24 and 24.3% respectively and using DASII, a diagnostic tool (13.3%). Also the combination of Amiel Tison angles, CDC standing grading and DDST gross motor against DASII motor DQ had high specificity (94.15%) and negative predictive value (NPV) (70.18%) but with a very low sensitivity of 14.58% and low positive predictive value (PPV) of 53.85%. It was observed that a significant odds ratio for DASII mental deviation quotient (DQ) was seen for neonatal seizures (2.34) and low birth weight (1.49).
  
  
  CONCLUSIONS
  The prevalence of developmental delay using the screening tools, CDC grading for standing, Amiel Tison angles and DDST II (Denver II) gross motor were 24.8, 24 and 24.3% respectively and together they had a high specificity, NPV and accuracy against DASII motor DQ as gold standard at one year assessment.
authors.affiliation: Child Development Centre, Thiruvananthapuram Medical College, Thiruvananthapuram, 695011, Kerala, India, cdcmkc@gmail.com.
authors.forename: M K C
authors.initials: MK
authors.lastname: Nair
authors.forename: Rajee
authors.initials: R
authors.lastname: Krishnan
authors.forename: G S
authors.initials: GS
authors.lastname: Harikumaran Nair
authors.forename: Babu
authors.initials: B
authors.lastname: George
authors.forename: Deepa
authors.initials: D
authors.lastname: Bhaskaran
authors.forename: M L
authors.initials: ML
authors.lastname: Leena
authors.forename: Paul Swamidhas Sudhakar
authors.initials: PS
authors.lastname: Russell
mesh_terms: D002657:Child Development; D002658:Developmental Disabilities / Q000175:diagnosis*; D006801:Humans; D007194:India; D007223:Infant