title: [An update in drug use during pregnancy: risk classification].
abstract: OBJECTIVE
  To review medicines pregnancy category and establish the degree of conformity between the two systems more used: FDA (Food and Drug Administration) and ACPM (advisory Committee on Prescription Medicines).
  
  
  METHODS
  drugs used in most frequent pathologies during pregnancy have been selected and found its pregnancy category according to FDA and ACPM. The degree of conformity has been established between both categorisation systems.
  
  
  RESULTS
  a total of 270 medicines were reviewed. 260 drugs had pregnancy category by FDA and 245 by ACPM system. 232 drugs had pregnancy category defined by both classifications (FDA and ACPM). We found 70,2% of them in the same pregnancy category.
  
  
  CONCLUSIONS
  The discrepancies found in both pregnancy categorisation systems can be confused in order to prescribe and know its safety statement of medicines during pregnancy which can limits its utility. It would be desirable more studies after medicines registered to get more information which could help to use safety drugs during pregnancy and minimize discrepancies between both pregnancy categorisation systems.
authors.affiliation: Servicio de Farmacia. Hospital Universitario del Henares. Coslada. Madrid.. mgallego.hulp@salud.madrid.org.
authors.forename: M
authors.initials: M
authors.lastname: Gallego Úbeda
authors.affiliation: Servicio de Farmacia. Hospital Universitario del Henares. Coslada. Madrid.. mgallego.hulp@salud.madrid.org.
authors.forename: L
authors.initials: L
authors.lastname: Delgado Téllez de Cepeda
authors.affiliation: Servicio de Farmacia. Hospital Universitario del Henares. Coslada. Madrid.. mgallego.hulp@salud.madrid.org.
authors.forename: M de Los A
authors.initials: Mde L
authors.lastname: Campos Fernández de Sevilla
authors.affiliation: Servicio de Farmacia. Hospital Universitario del Henares. Coslada. Madrid.. mgallego.hulp@salud.madrid.org.
authors.forename: A
authors.initials: A
authors.lastname: De Lorenzo Pinto
authors.affiliation: Servicio de Farmacia. Hospital Universitario del Henares. Coslada. Madrid.. mgallego.hulp@salud.madrid.org.
authors.forename: F
authors.initials: F
authors.lastname: Tutau Gómez
mesh_terms: D005260:Female; D006801:Humans; D011247:Pregnancy; D055553:Prescription Drugs / Q000145:classification* / Q000627:therapeutic use*; D018570:Risk Assessment
chemical_list: D055553:Prescription Drugs