title: The antimicrobial activity of fruits from some cultivar varieties of Rubus idaeus and Rubus occidentalis.
abstract: Raspberries, derived from different cultivar varieties, are a popular ingredient of everyday diet, and their biological activity is a point of interest for researchers. The ethanol-water extracts from four varieties of red (Rubus idaeus'Ljulin', 'Veten', 'Poranna Rosa') and black (Rubus occidentalis'Litacz') raspberries were evaluated in the range of their antimicrobial properties as well as phenolic content - sanguiin H-6, free ellagic acid and anthocyanins. The antimicrobial assay was performed with the use of fifteen strains of bacteria, both Gram-negative and Gram-positive. The antimicrobial activity of the extracts varied and depended on the analysed strain of bacteria and cultivar variety, with the exception of Helicobacter pylori, towards which the extracts displayed the same growth inhibiting activity. Two human pathogens Corynebacterium diphtheriae and Moraxella catarrhalis proved to be the most sensitive to raspberry extracts. Contrary to the extracts, sanguiin H-6 and ellagic acid were only active against eight and nine bacterial strains, respectively. The determined MIC and MBC values of both compounds were several times lower than the tested extracts. The highest sensitivity of Corynebacterium diphtheriae to extracts from both black and red raspberries may be due to its sensitivity to sanguiin H-6 and ellagic acid.
authors.affiliation: Department of Pharmacognosy with Medicinal Plant Garden, Faculty of Pharmacy with Subfaculty of Laboratory Medicine, Medical University of Gdańsk, Al. Gen. J. Hallera 107, 80-416 Gdańsk, Poland. krauze@gumed.edu.pl.
authors.forename: M
authors.initials: M
authors.lastname: Krauze-Baranowska
authors.forename: M
authors.initials: M
authors.lastname: Majdan
authors.forename: R
authors.initials: R
authors.lastname: Hałasa
authors.forename: D
authors.initials: D
authors.lastname: Głód
authors.forename: M
authors.initials: M
authors.lastname: Kula
authors.forename: I
authors.initials: I
authors.lastname: Fecka
authors.forename: A
authors.initials: A
authors.lastname: Orzeł
mesh_terms: D000872:Anthocyanins / Q000032:analysis / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000032:analysis / Q000494:pharmacology*; D002851:Chromatography, High Pressure Liquid; D003353:Corynebacterium diphtheriae / Q000187:drug effects; D004610:Ellagic Acid / Q000032:analysis / Q000494:pharmacology*; D005638:Fruit / Q000737:chemistry*; D016480:Helicobacter pylori / Q000187:drug effects; D006863:Hydrogen-Ion Concentration; D047348:Hydrolyzable Tannins / Q000032:analysis / Q000494:pharmacology*; D001936:Moraxella catarrhalis / Q000187:drug effects; D010936:Plant Extracts / Q000032:analysis / Q000494:pharmacology; D065856:Rubus / Q000737:chemistry*
chemical_list: D000872:Anthocyanins; D000890:Anti-Infective Agents; D047348:Hydrolyzable Tannins; D010936:Plant Extracts; D004610:Ellagic Acid; C081844:sanguiin H 6