title: AgONO-assisted direct C-H arylation of heteroarenes with anilines.
abstract: A novel copper-catalyzed C-H arylation of heteroarenes with anilines by an in situ diazonium reaction is established by using silver nitrite (AgONO) as an unconventional nitrosating reagent under acid-free conditions. It provides a complementary approach for the C-H arylation of electron-rich heteroarenes with aromatic amines affording a variety of heterobiaryls in moderate to good yields.
authors.affiliation: Organic Chemistry, Institute of Chemical and Engineering Sciences (ICES), 8 Biomedical Grove, Neuros #07-01, Singapore 138665. jayasree_seayad@ices.a-star.edu.sg.
authors.forename: Saravanan
authors.initials: S
authors.lastname: Gowrisankar
authors.forename: Jayasree
authors.initials: J
authors.lastname: Seayad
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003979:Diazonium Compounds / Q000737:chemistry*; D006841:Hydrocarbons, Aromatic / Q000737:chemistry*; D009573:Nitrites / Q000737:chemistry*; D018030:Silver Compounds / Q000737:chemistry*
chemical_list: D000814:Aniline Compounds; D003979:Diazonium Compounds; D006841:Hydrocarbons, Aromatic; D009573:Nitrites; D018030:Silver Compounds; D003300:Copper; C023650:aniline
keywords: CH arylation; copper acetate; diazonium reaction; heteroarenes; silver nitrite