title: Aplasia of the septum transversum has no effect on plasma biochemistry following an acute hypoxic event in Atlantic salmon.
abstract: Aplasia of the septum transversum (AST) is a malformation that results in alterations in ventricle morphology. The condition has been linked to increased mortality during periods of increased cardiac demand in Atlantic salmon Salmo salar. The blood plasma biochemical response to an acute hypoxic event (1 h at 31-39% O₂saturation) was investigated in fish with and without a septum transversum to assess levels of anaerobic respiration (lactate) and the stress response (cortisol, glucose, osmolality, Na⁺, Cl⁻ and K⁺). AST had no effect on body size parameters or relative ventricular mass. The hypoxic event increased the levels of anaerobic respiration and induced a typical stress response. Contrary to our expectations, AST had no effect on any plasma parameter in normoxia or following severe acute hypoxia. We conclude that in the current scenario, AST does not affect the levels of anaerobic respiration or the plasma stress response in Atlantic salmon.
authors.affiliation: Department of Production Animal Clinical Sciences, Norwegian School of Veterinary Science, 0033 Oslo, Norway.
authors.forename: Thomas W K
authors.initials: TW
authors.lastname: Fraser
authors.forename: Per Gunnar
authors.initials: PG
authors.lastname: Fjelldal
authors.forename: Tom J
authors.initials: TJ
authors.lastname: Hansen
authors.forename: Frode
authors.initials: F
authors.lastname: Oppedal
authors.forename: Rolf Erik
authors.initials: RE
authors.lastname: Olsen
authors.forename: Tone
authors.initials: T
authors.lastname: Vågseth
authors.forename: Mette
authors.initials: M
authors.lastname: Remen
mesh_terms: D000818:Animals; D005393:Fish Diseases / Q000097:blood / Q000151:congenital*; D006330:Heart Defects, Congenital / Q000097:blood / Q000662:veterinary*; D000860:Hypoxia / Q000097:blood / Q000662:veterinary*; D020317:Salmo salar / Q000097:blood*; D013312:Stress, Physiological; D013997:Time Factors