title: Copper(II) catalyzed expeditious synthesis of furoquinoxalines through a one-pot three-component coupling strategy.
abstract: Microwave assisted one-pot transformation has been developed for the synthesis of biologically significant polysubstituted furoquinoxalines in good to excellent yields through a copper(II) catalyzed three-component coupling of o-phenylenediamine, ethylglyoxalate, and terminal alkyne, known as A(3)-coupling, followed by 5-endo-dig cyclization.
authors.affiliation: Medicinal and Process Chemistry Division, §Molecular and Structural Biology Division, CSIR-Central Drug Research Institute , Lucknow-226 031, India.
authors.forename: Gunaganti
authors.initials: G
authors.lastname: Naresh
authors.forename: Ruchir
authors.initials: R
authors.lastname: Kant
authors.forename: Tadigoppula
authors.initials: T
authors.lastname: Narender
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis* / Q000737:chemistry; D008698:Mesylates / Q000737:chemistry; D008872:Microwaves; D015394:Molecular Structure; D010655:Phenylenediamines / Q000737:chemistry
chemical_list: D000480:Alkynes; D006576:Heterocyclic Compounds, 4 or More Rings; D008698:Mesylates; D010655:Phenylenediamines; D003300:Copper; C034193:1,2-diaminobenzene; C012077:trifluoromethanesulfonic acid