title: Wandering pneumonia caused by dabigatran.
abstract: We herein describe the case of a 74-year-old man who experienced pulmonary consolidation and chest pain following administration of dabigatran, a novel oral anticoagulant. The consolidation settled spontaneously in another lung area, a condition sometimes referred to as "wandering pneumonia." Although we did not find specific pathological evidence of interstitial lung disease on transbronchial lung biopsy, a lung opacity spontaneously disappeared following discontinuance of dabigatran, and there was no recurrence. There are no other reports of dabigatran-induced lung injury, except alveolar hemorrhage and eosinophilic pneumonia. We should consider that any novel drug could cause various types of pulmonary injuries.
authors.affiliation: Department of Pulmonary Medicine, Tokyo Rosai Hospital, Japan.
authors.forename: Masakazu
authors.initials: M
authors.lastname: Kono
authors.forename: Kousuke
authors.initials: K
authors.lastname: Hirota
authors.forename: Ayako
authors.initials: A
authors.lastname: Yokoe
authors.forename: Chie
authors.initials: C
authors.lastname: Koumura
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Sakai
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Tojima
mesh_terms: D000368:Aged; D000991:Antithrombins / Q000008:administration & dosage / Q000009:adverse effects*; D001562:Benzimidazoles / Q000008:administration & dosage / Q000009:adverse effects*; D000069604:Dabigatran; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008297:Male; D011014:Pneumonia / Q000139:chemically induced* / Q000000981:diagnostic imaging*; D011859:Radiography; D012075:Remission, Spontaneous; D015091:beta-Alanine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*
chemical_list: D000991:Antithrombins; D001562:Benzimidazoles; D015091:beta-Alanine; D000069604:Dabigatran