title: [The progress of sperm functional proteins regulating the process of fertilization].
abstract: The process of mammalian fertilization involves a series of sperm functional activities, including the sperm transportation, hyperactivation and capacitation, acrosome reaction and sperm-egg fusion, etc. The semen proteins play indispensable roles in these processes, and they are closely associated with the fecundity of males. So these proteins can be biomarkers to evaluate the fertilization capacity of mammalian semen. In this review, we mainly introduce some semen proteins relevant to spermatozoa functions and illustrate their important regulatory roles on the fertilization processes, involving spermatozoa motility, capacitation, acrosome reaction, penetrating the zona pellucida and sperm-egg fusion, etc. Moreover, their potential applications in the evaluation of heredity in livestock are also summarized.
authors.affiliation: National Engineering Research Center For Breeding Swine Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
authors.forename: Zhilin
authors.initials: Z
authors.lastname: Chen
authors.affiliation: National Engineering Research Center For Breeding Swine Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
authors.forename: Meiying
authors.initials: M
authors.lastname: Feng
authors.affiliation: National Engineering Research Center For Breeding Swine Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
authors.forename: Yuming
authors.initials: Y
authors.lastname: Chen
authors.affiliation: National Engineering Research Center For Breeding Swine Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
authors.forename: Hengxi
authors.initials: H
authors.lastname: Wei
authors.affiliation: National Engineering Research Center For Breeding Swine Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
authors.forename: Li
authors.initials: L
authors.lastname: Li
authors.affiliation: Dongguan Institute of Animal Science, Dongguan 523086, China.
authors.forename: Tongshan
authors.initials: T
authors.lastname: Wu
authors.affiliation: National Engineering Research Center For Breeding Swine Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
authors.forename: Shouquan
authors.initials: S
authors.lastname: Zhang
mesh_terms: D000818:Animals; D005306:Fertilization; D006801:Humans; D008297:Male; D011506:Proteins / Q000378:metabolism*; D013094:Spermatozoa / Q000166:cytology / Q000378:metabolism* / Q000502:physiology
chemical_list: D011506:Proteins