title: [Lactic acidosis in a child with acute severe asthma].
abstract: Lactic acidosis is a recognized event in adult patients with acute severe asthma (ASA). Only a few cases have been reported in children. Hereinafter is reported the case of a 2-year-old girl hospitalized in the pediatric intensive care unit for ASA, which was treated with high-flow oxygen therapy and intravenous methylprednisolone and salbutamol. During hospitalization, she had metabolic acidosis with a 7.29 pH, a 26mmHg hypocapnia, and a decrease in bicarbonates to 12 mmol/L. The anion gap was increased to 20 mmol/L and lactates to 8 mmol/L. The work-up for a congenital metabolic disease was normal. Progression was propitious with spontaneous improvement of lactic acidosis, and the child was discharged from the intensive care unit after 72 h. The origin of lactic acidosis during ASA seems to be multifactorial. Although its recovery can be spontaneous, it is important to know how to identify it because it can worsen respiratory symptoms and can lead to incongruous therapeutic escalation.
authors.affiliation: Service de réanimation pédiatrique, CHU Estaing, 1, place Raymond et Lucie Aubrac, 63003 Clermont-Ferrand, France. Electronic address: ceperrin63@gmail.com.
authors.forename: C
authors.initials: C
authors.lastname: Perrin
authors.affiliation: Service de réanimation pédiatrique, CHU Estaing, 1, place Raymond et Lucie Aubrac, 63003 Clermont-Ferrand, France.
authors.forename: N
authors.initials: N
authors.lastname: Savy
authors.affiliation: Service de réanimation pédiatrique, CHU Estaing, 1, place Raymond et Lucie Aubrac, 63003 Clermont-Ferrand, France.
authors.forename: M
authors.initials: M
authors.lastname: Lang
authors.affiliation: Service des urgences pédiatriques, CHU Estaing, 1, place Raymond et Lucie Aubrac, 63003 Clermont-Ferrand, France.
authors.forename: N
authors.initials: N
authors.lastname: Caron
authors.affiliation: Service de réanimation pédiatrique, CHU Estaing, 1, place Raymond et Lucie Aubrac, 63003 Clermont-Ferrand, France; Service des urgences pédiatriques, CHU Estaing, 1, place Raymond et Lucie Aubrac, 63003 Clermont-Ferrand, France.
authors.forename: A
authors.initials: A
authors.lastname: Labbé
mesh_terms: D000140:Acidosis, Lactic / Q000150:complications* / Q000175:diagnosis; D001249:Asthma / Q000150:complications* / Q000628:therapy; D002675:Child, Preschool; D005260:Female; D006801:Humans; D016857:Hypocapnia / Q000150:complications / Q000175:diagnosis; D015278:Intensive Care Units, Pediatric; D012720:Severity of Illness Index