title: [Symptom control and place of death in palliative cancer patients in primary care. Results of the controlled PAMINO evaluation study].
abstract: BACKGROUND
  The care of patients at the end of life focuses on preservation of the quality of life, symptom control and fulfillment of the preferred place of death. Only few care and outcome-related data for primary palliative care in Germany are available; therefore, the objective was to examine the quality of life, symptom control and place of death of patients with palliative treatment by general practitioners (GP).
  
  
  METHODS
  The study is part of the PAMINO project, a non-randomized, controlled trial evaluating the effectiveness of continuing medical education for GPs (≥ 40 h) in palliative care (ISRCTN78021852). Cancer patients with an estimated life expectancy of less than 6 months were recruited by GPs with (PG) or without (CG) continuing education and documented the diagnosis, medication based on the hospice and palliative care collation ( Hospiz- und Palliativ-Erfassung, HOPE) core documentation and the preferred place of death. Patients rated their symptom burden and health-related quality of life using the quality of life questionnaire (QLQ-C15-PAL). Baseline (t0) data at enrollment and the last individual (t1) assessment were used for the analysis.
  
  
  RESULTS
  Data of 68 patients (PG: n = 43, CG: n = 25, mean age 69.2 ± 12 years, average time since cancer diagnosis 14 months) were available at t0 and t1 (mean period 4.0 ± 2.1 months). Physical function decreased while emotional functioning remained stable. Patient-perceived pain did not increase; however, GPs intensified the pain therapy. The PGs prescribed non-opioid analgesics more frequently than CGs. During the observation period 59 patients died of which 40 out of 48 (83 %) as preferred at home.
  
  
  CONCLUSIONS
  Stable emotional functioning, good symptom control in cancer patients at the end of life and the high rate of dying at home as preferred suggest that GPs with specific training can ensure high-quality general palliative care.
authors.affiliation: Abteilung Allgemeinmedizin und Versorgungsforschung, Universitätsklinikum Heidelberg, Voßstr. 2, Gebäude 37, 69115, Heidelberg, Deutschland, peter.engeser@med.uni-heidelberg.de.
authors.forename: P
authors.initials: P
authors.lastname: Engeser
authors.forename: K
authors.initials: K
authors.lastname: Hermann
authors.forename: J
authors.initials: J
authors.lastname: Szecsenyi
authors.forename: F
authors.initials: F
authors.lastname: Peters-Klimm
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004502:Education, Medical, Continuing; D005260:Female; D058006:General Practice / Q000193:education; D005858:Germany; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000523:psychology / Q000628:therapy*; D010147:Pain Measurement; D010166:Palliative Care / Q000379:methods* / Q000523:psychology; D011320:Primary Health Care; D011787:Quality of Health Care; D011788:Quality of Life / Q000523:psychology; D012111:Residence Characteristics; D011795:Surveys and Questionnaires