title: Evaluation of neutrophil function during hemodialysis treatment in healthy dogs under anesthesia with sevoflurane.
abstract: This study evaluated the number and function of neutrophils during 3 hr of hemodialysis in healthy dogs under anesthesia. Isolated neutrophils were used to assess neutrophil adhesion, phagocytosis and the oxidative burst. At 0.5 and 3 hr after the start of hemodialysis treatment, there was a decrease in neutrophil number. The phagocytic ability of neutrophils was decreased 3 hr after the start of hemodialysis. In conclusion, this study demonstrated that hemodialysis reduces the number and phagocytic ability of neutrophils during treatment. However, these changes recover within 24 hr of hemodialysis.
authors.affiliation: Cooperative Department of Veterinary Clinical Medicine, Iwate University, Morioka, Iwate 020-8550, Japan.
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Shimamura
authors.forename: Ken
authors.initials: K
authors.lastname: Kimura
authors.forename: Masaaki
authors.initials: M
authors.lastname: Katayama
authors.forename: Tadahisa
authors.initials: T
authors.lastname: Mashita
authors.forename: Kenichi
authors.initials: K
authors.lastname: Maeda
authors.forename: Saori
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Reeko
authors.initials: R
authors.lastname: Sato
authors.forename: Jun
authors.initials: J
authors.lastname: Yasuda
mesh_terms: D018685:Anesthetics, Inhalation; D000818:Animals; D001806:Blood Urea Nitrogen; D002448:Cell Adhesion / Q000502:physiology; D002452:Cell Count; D004285:Dogs; D005434:Flow Cytometry; D008738:Methyl Ethers; D009504:Neutrophils / Q000502:physiology*; D010587:Phagocytosis / Q000502:physiology; D006435:Renal Dialysis / Q000009:adverse effects* / Q000379:methods / Q000662:veterinary*; D016897:Respiratory Burst / Q000502:physiology; D000077149:Sevoflurane; D013997:Time Factors
chemical_list: D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane