title: Donor height in combination with islet donor score improves pancreas donor selection for pancreatic islet isolation and transplantation.
abstract: To maximize the islet isolation yield for successful islet transplantation, the key task has been to identify an ideal pancreas donor. Since implementation of the islet donor score in donor selection, we have consistently obtained higher islet yields and transplantation rates. In this study, we tested whether assessing donor height as an independent variable in combination with the donor score could improve the pancreas donor selection. Donor and islet isolation information (n = 22) were collected and studied between 2011 and 2012. Pearson correlation analysis was used in statistical analysis. Donor height as an independent variable was significantly correlated to the weight of the pancreas, pre-Islet Equivalents (pre-IEQ), post-IEQ, and IDS (P < .05). When donor with height of 179 cm ± 3 was selected in combination with IDS > 80, the clinical islet transplantation rate reached 80%.
authors.affiliation: Department of Surgery, Division of Abdominal Organ Transplantation, The University of Chicago, Chicago, IL.
authors.forename: L J
authors.initials: LJ
authors.lastname: Wang
authors.affiliation: Department of Surgery, Division of Abdominal Organ Transplantation, The University of Chicago, Chicago, IL.
authors.forename: O
authors.initials: O
authors.lastname: Cochet
authors.affiliation: Department of Surgery, Division of Abdominal Organ Transplantation, The University of Chicago, Chicago, IL; Institute of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University, Chongqing, China.
authors.forename: X J
authors.initials: XJ
authors.lastname: Wang
authors.affiliation: Department of Surgery, Division of Abdominal Organ Transplantation, The University of Chicago, Chicago, IL.
authors.forename: A
authors.initials: A
authors.lastname: Krzystyniak
authors.affiliation: Department of Surgery, Division of Abdominal Organ Transplantation, The University of Chicago, Chicago, IL.
authors.forename: R
authors.initials: R
authors.lastname: Misawa
authors.affiliation: Department of Surgery, Division of Abdominal Organ Transplantation, The University of Chicago, Chicago, IL.
authors.forename: K
authors.initials: K
authors.lastname: Golab
authors.affiliation: Department of Surgery, Division of Abdominal Organ Transplantation, The University of Chicago, Chicago, IL.
authors.forename: M
authors.initials: M
authors.lastname: Tibudan
authors.affiliation: Department of Surgery, Division of Abdominal Organ Transplantation, The University of Chicago, Chicago, IL.
authors.forename: R
authors.initials: R
authors.lastname: Grose
authors.affiliation: Department of Surgery, Division of Abdominal Organ Transplantation, The University of Chicago, Chicago, IL.
authors.forename: O
authors.initials: O
authors.lastname: Savari
authors.affiliation: Department of Surgery, Division of Abdominal Organ Transplantation, The University of Chicago, Chicago, IL.
authors.forename: J M
authors.initials: JM
authors.lastname: Millis
authors.affiliation: Department of Surgery, Division of Abdominal Organ Transplantation, The University of Chicago, Chicago, IL. Electronic address: pwitkowski@surgery.bsd.uchicago.edu.
authors.forename: P
authors.initials: P
authors.lastname: Witkowski
mesh_terms: D001827:Body Height; D015992:Body Mass Index; D001835:Body Weight; D046148:Donor Selection; D006801:Humans; D016381:Islets of Langerhans Transplantation; D009929:Organ Size; D010179:Pancreas / Q000473:pathology; D011237:Predictive Value of Tests; D012189:Retrospective Studies