title: The making of the master clock.
abstract: A genetic basis for the anatomic master circadian clock in mammals has been found.
authors.affiliation: Ethan Buhr is in the Department of Ophthalmology, University of Washington Medical School, Seattle, United States.
authors.forename: Ethan
authors.initials: E
authors.lastname: Buhr
authors.affiliation: Russell N Van Gelder is in the Departments of Ophthalmology, Biological Structure, and Pathology, University of Washington Medical School, Seattle, United States russvg@u.washington.edu.
authors.forename: Russell N
authors.initials: RN
authors.lastname: Van Gelder
mesh_terms: D000818:Animals; D057906:Circadian Clocks / Q000235:genetics*; D020179:Jet Lag Syndrome / Q000235:genetics*; D060850:LIM-Homeodomain Proteins / Q000235:genetics*; D008297:Male; D009474:Neurons / Q000378:metabolism*; D056950:Period Circadian Proteins / Q000235:genetics*; D013493:Suprachiasmatic Nucleus / Q000378:metabolism*; D014157:Transcription Factors / Q000235:genetics*
chemical_list: D060850:LIM-Homeodomain Proteins; C499523:Lhx1 protein, mouse; D056950:Period Circadian Proteins; D014157:Transcription Factors
keywords: Lhx1; Ror-alpha; VIP; circadian rhythms; suprachiasmatic nucleus