title: Clinical features of docetaxel chemotherapy-related lymphedema.
abstract: Lymphedema is a chronic, progressive, and multifactorial disease. The anticancer drug docetaxel (Taxotere) can lead to fluid retention, which is the main cause of peripheral edema of the extremities, pleural effusion, pericardial effusion, and ascites in patients undergoing chemotherapy. While there have been a few case reports documenting fluid retention-induced edema as a side effect of docetaxel, it is not yet clear whether docetaxel causes lymphedema directly. Here, we report cases of three patients who developed lymphedema after treatment with docetaxel.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Kosin University College of Medicine , Busan, Korea.
authors.forename: Sae In
authors.initials: SI
authors.lastname: Park
authors.forename: Woo Hyun
authors.initials: WH
authors.lastname: Jeon
authors.forename: Ho Joong
authors.initials: HJ
authors.lastname: Jeung
authors.forename: Ghi Chan
authors.initials: GC
authors.lastname: Kim
authors.forename: Dong Kyu
authors.initials: DK
authors.lastname: Kim
authors.forename: Young-Joo
authors.initials: YJ
authors.lastname: Sim
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000601:surgery*; D003131:Combined Modality Therapy; D000077143:Docetaxel; D005260:Female; D006801:Humans; D008209:Lymphedema / Q000139:chemically induced*; D008875:Middle Aged; D043823:Taxoids / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D043823:Taxoids; D000077143:Docetaxel