title: Et3N-catalyzed tandem formal [4 + 3] annulation/decarboxylation/isomerization of methyl coumalate with imine esters: access to functionalized azepine derivatives.
abstract: An unprecedented catalytic tandem formal [4 + 3] cycloaddition/decarboxylation/isomerization of methyl coumalate and imine esters is successfully developed. This tandem reaction only requires Et3N as the mild base affording a series of highly functionalized seven-membered heterocyclic azepine derivatives in good yields with excellent regioselectivities.
authors.affiliation: College of Chemistry and Molecular Sciences, Wuhan University , Wuhan, China 430072.
authors.forename: Kang
authors.initials: K
authors.lastname: Liu
authors.forename: Huai-Long
authors.initials: HL
authors.lastname: Teng
authors.forename: Chun-Jiang
authors.initials: CJ
authors.lastname: Wang