title: RESICstance is futile-but not in glioblastoma.
abstract: Genomic alterations that occur early in tumorigenesis represent fundamental diver lesions and are perhaps of highest priority as a means to intervene therapeutically. In this issue of Cancer Cell, Ozawa and colleagues apply an algorithm to identify early events in glioblastoma and validate their findings in a rigorous manner.
authors.affiliation: Department of Neurosurgery, University Health Network, Adult Brain Tumour Program at Princess Margaret Cancer Centre, University of Toronto, Toronto ON M5S 2J7, Canada.
authors.forename: Gelareh
authors.initials: G
authors.lastname: Zadeh
authors.affiliation: Department of Pathology, University Health Network, Adult Brain Tumour Program at Princess Margaret Cancer Centre, University of Toronto, Toronto ON M5S 2J7, Canada. Electronic address: kaldape@uhnresearch.ca.
authors.forename: Kenneth
authors.initials: K
authors.lastname: Aldape
mesh_terms: D000818:Animals; D001932:Brain Neoplasms / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000235:genetics*; D005909:Glioblastoma / Q000473:pathology*; D006801:Humans