title: [Adnexal neoplasms in the context of skin cancer: trichilemmal carcinoma. Apropos of a case].
abstract: BACKGROUND
  The trichilemmal carcinoma is a rare malignant neoplasm, whose origin lies in the annexes of the skin, because of its low prevalence often confused with other dermal tumors, the differential diagnosis is not easy and is usually made by exclusion; in theory, its behavior is slow with little tendency to send both regional lymph node metastasis and systemic. Due to the limited number of cases there is no consensus on the prognosis, although it is generally considered good. The aim of this report is to show a case that, contrary to previous reports, the clinical presentation is aggressive with large soft tissue tumor infiltration around the site of origin in a patient without risk factors for skin cancer.
  
  
  METHODS
  Male patient, 65 years old with cytologic diagnosis of carcinoma in a preprarotideal facial tumor, characteristics at diagnosis were infiltration of the facial skin, ear, and parotid gland. Complete block resection was performed, radical parotiroidectomy and radical neck dissection; the soft tissue defect was covered with a pediculated flap. The evolution was satisfactory it follow-up short though. We evaluated the experience in the literature regarding the prognosis and treatment of these patients.
  
  
  CONCLUSIONS
  Trichilemmal carcinoma can be fully invasive behavior prognosis is difficult to know and probably depends on the clinical stage at diagnosis.
authors.affiliation: Departamento de Tumores de Cabeza y Cuello, Hospital de Oncología, CMN Siglo XXI. Instituto Mexicano del Seguro Social, Mexico DF, Mexico.
authors.forename: Ignacio Jaime
authors.initials: IJ
authors.lastname: Pérez-Martínez
authors.affiliation: Departamento de Patología, Hospital de Oncología, CMN Siglo XXI. Instituto Mexicano del Seguro Social, Mexico DF, Mexico.
authors.forename: Alejandra
authors.initials: A
authors.lastname: Mantilla-Morales
authors.affiliation: Departamento de Tumores de Cabeza y Cuello, Hospital de Oncología, CMN Siglo XXI. Instituto Mexicano del Seguro Social, Mexico DF, Mexico.
authors.forename: Iván
authors.initials: I
authors.lastname: Cruz-Esquivel
authors.affiliation: Departamento de Tumores de Cabeza y Cuello, Hospital de Oncología, CMN Siglo XXI. Instituto Mexicano del Seguro Social, Mexico DF, Mexico. gal61@prodigy.net.mx govame@gmail.com.
authors.forename: José Francisco
authors.initials: JF
authors.lastname: Gallegos-Hernández
mesh_terms: D000368:Aged; D018280:Carcinoma, Skin Appendage / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D004431:Ear, External / Q000473:pathology / Q000601:surgery; D005153:Facial Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D015603:Keratinocytes / Q000473:pathology; D008297:Male; D037981:Neck Dissection; D009361:Neoplasm Invasiveness; D010306:Parotid Gland / Q000473:pathology / Q000601:surgery; D010614:Pharynx / Q000473:pathology / Q000601:surgery; D012878:Skin Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D013524:Surgical Flaps
keywords: Trichilemmal carcinoma; carcinoma triquilemal; cáncer de piel; skin cancer; tumor de anexos; tumor of annexes