title: Kinetic Resolution of Diiron Acyl Complexes-An Approach to Asymmetric Bicyclic β-Lactams.
abstract: Kinetic resolution is achieved in the reaction of racemic diiron complexes like 1 with the chiral nitrone (-)-2. Oxidative removal of the metal and reductive cleavage of the N-O bond provides β-amino acids. This sequence was used in the synthesis of β-amino acids as well as the corresponding β-lactams 4 (via 3).
authors.affiliation: Department of Chemistry, Washington University, St. Louis, Missouri 63130, USA, Fax: (+1) 314-935-4481. srg@wuchem.wustl.edu.
authors.forename: S R
authors.initials: SR
authors.lastname: Gilbertson
authors.forename: O D
authors.initials: OD
authors.lastname: Lopez
keywords: Asymmetric synthesis; Cycloadditions; Iron; Lactams