title: [Perioperative considerations for performing a brain biopsy on a patient with subtype VV2 sporadic Creutzfeldt-Jakob disease].
abstract: Creutzfeldt-Jakob disease (CJD) is the most common transmissible spongiform encephalopathy. It is an infectious, progressive, degenerative neurological disorder, with a presumably long incubation period, but a rapid fatal course. CJD is transmitted by a proteinaceous infectious agent, or «prion». Because the prions are difficult to eradicate and are resistant to the currently used sterilization methods, special precautions must be taken with all surgical instruments. It is recommended the single-use equipment, destruction of contaminated equipment, decontamination of reusable instruments, use of protective clothing, and storing and quarantining surgical instruments. The single-use equipment and some tissues and body fluids from the patient with CJD are highly infectious and must be incinerated. We report a case of a patient who had undergone brain biopsy for suspected of CJD, being confirmed to have sporadic CJD. Specific preventive measures were taken to reduce the risk of transmission to healthcare workers.
authors.affiliation: UGC Bloque Quirúrgico Hospital de Traumatología y Rehabilitación, Servicio de Anestesiología y Reanimación, Departamento de Neuroanestesia, Hospital Virgen del Rocío, Sevilla, España. Electronic address: rosanabixi7@hotmail.com.
authors.forename: R
authors.initials: R
authors.lastname: Guerrero-Domínguez
authors.affiliation: UGC Bloque Quirúrgico Hospital de Traumatología y Rehabilitación, Servicio de Anestesiología y Reanimación, Departamento de Neuroanestesia, Hospital Virgen del Rocío, Sevilla, España.
authors.forename: R
authors.initials: R
authors.lastname: Rubio-Romero
authors.affiliation: UGC Bloque Quirúrgico Hospital de Traumatología y Rehabilitación, Servicio de Anestesiología y Reanimación, Departamento de Neuroanestesia, Hospital Virgen del Rocío, Sevilla, España.
authors.forename: G
authors.initials: G
authors.lastname: González-González
authors.affiliation: UGC Bloque Quirúrgico Hospital de Traumatología y Rehabilitación, Servicio de Anestesiología y Reanimación, Departamento de Neuroanestesia, Hospital Virgen del Rocío, Sevilla, España.
authors.forename: I
authors.initials: I
authors.lastname: Jiménez
mesh_terms: D001706:Biopsy / Q000379:methods*; D001921:Brain / Q000473:pathology*; D003264:Containment of Biohazards / Q000379:methods*; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis / Q000473:pathology* / Q000517:prevention & control / Q000635:transmission; D004866:Equipment Contamination / Q000517:prevention & control; D006801:Humans; D017758:Infectious Disease Transmission, Patient-to-Professional / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D009873:Operating Rooms; D019990:Perioperative Care / Q000379:methods*; D011481:Protective Clothing
keywords: Anestesia; Anesthesia; Biopsia cerebral; Brain biopsy; Control de la infección; Creutzfeldt-Jakob disease; Encefalopatía espongiforme transmisible; Enfermedad de Creutzfeldt-Jakob; Infection control; Procedimientos quirúrgicos; Surgical procedures; Transmissible spongiform encephalopathy