title: Lab-on-a-chip reactor imaging with unprecedented chemical resolution by Hadamard-encoded remote detection NMR.
abstract: The development of microfluidic processes requires information-rich detection methods. Here we introduce the concept of remote detection exchange NMR spectroscopy (RD-EXSY), and show that, along with indirect spatial information extracted from time-of-flight data, it provides unique information about the active regions, reaction pathways, and intermediate products in a lab-on-a-chip reactor. Furthermore, we demonstrate that direct spatial resolution can be added to RD-EXSY efficiently by applying the principles of Hadamard spectroscopy.
authors.affiliation: NMR Research Group, Department of Physics, University of Oulu, P.O. Box 3000, 90014 Oulu (Finland) http://cc.oulu.fi/∼nmrwww/. ville-veikko.telkki@oulu.fi.
authors.forename: Ville-Veikko
authors.initials: VV
authors.lastname: Telkki
authors.forename: Vladimir V
authors.initials: VV
authors.lastname: Zhivonitko
authors.forename: Anne
authors.initials: A
authors.lastname: Selent
authors.forename: Gianmario
authors.initials: G
authors.lastname: Scotti
authors.forename: Jarmo
authors.initials: J
authors.lastname: Leppäniemi
authors.forename: Sami
authors.initials: S
authors.lastname: Franssila
authors.forename: Igor V
authors.initials: IV
authors.lastname: Koptyug
keywords: Hadamard spectroscopy; NMR spectroscopy; lab-on-a-chip; microfluidics; reactor imaging