title: Emerging roles of RNA modification: m(6)A and U-tail.
abstract: Although more than 100 types of RNA modification have been described thus far, most of them were thought to be rare in mRNAs and in regulatory noncoding RNAs. Recent developments have unveiled that at least some of the modifications are considerably abundant and widely conserved. This Minireview summarizes the molecular machineries and biological functions of methylation (N6-methyladenosine, m(6)A) and uridylation (U-tail).
authors.affiliation: IBS Center for RNA Research, Institute for Basic Science, Seoul 151-742, Korea; School of Biological Sciences, Seoul National University, Seoul 151-742, Korea.
authors.forename: Mihye
authors.initials: M
authors.lastname: Lee
authors.affiliation: IBS Center for RNA Research, Institute for Basic Science, Seoul 151-742, Korea; School of Biological Sciences, Seoul National University, Seoul 151-742, Korea.
authors.forename: Boseon
authors.initials: B
authors.lastname: Kim
authors.affiliation: IBS Center for RNA Research, Institute for Basic Science, Seoul 151-742, Korea; School of Biological Sciences, Seoul National University, Seoul 151-742, Korea. Electronic address: narrykim@snu.ac.kr.
authors.forename: V Narry
authors.initials: VN
authors.lastname: Kim
mesh_terms: D000818:Animals; D006801:Humans; D008745:Methylation; D035683:MicroRNAs / Q000378:metabolism; D009713:Nucleotidyltransferases / Q000378:metabolism; D012323:RNA Processing, Post-Transcriptional; D012333:RNA, Messenger / Q000378:metabolism*; D014542:Uridine Monophosphate / Q000378:metabolism
chemical_list: D035683:MicroRNAs; D012333:RNA, Messenger; D014542:Uridine Monophosphate; D009713:Nucleotidyltransferases