title: Nine additional complete genome sequences of HCV genotype 6 from Vietnam including new subtypes 6xb and 6xc.
abstract: We completely sequenced nine HCV-6 variants from Vietnam. They are grouped into six lineages beyond the 24 assigned subtypes, 6a-6xa, and 14 unclassified lineages that have been recently described with full-length genomes. Co-analysis with reference sequences in the NS5B region identified additional 22 such lineages, which made the total taxonomic number of HCV-6 increased to 66 that might be recognized at the subtype level. Because two of these six lineages revealed in this study each had >3 epidemiologically unlinked isolates identified, we proposed to assign them new subtypes 6xb and 6xc in following the eXtended format recently recommended in the expanded HCV nomenclature.
authors.affiliation: Department of Pathology and Laboratory Medicine, Center for Viral Oncology, University of Kansas Medical Center, MS 3046, 3901 Rainbow Boulevard, Kansas City, KS 66160, United States of America.
authors.forename: Chunhua
authors.initials: C
authors.lastname: Li
authors.affiliation: Center for Molecular Biomedicine, School of Medicine, University of Medicine and Pharmacy in Ho Chi Minh City, Ho Chi Minh City, Vietnam; Molecular Diagnostics Section, The NK-BIOTEK Laboratory, Ho Chi Minh City, Vietnam.
authors.forename: Van H
authors.initials: VH
authors.lastname: Pham
authors.affiliation: Center for Molecular Biomedicine, School of Medicine, University of Medicine and Pharmacy in Ho Chi Minh City, Ho Chi Minh City, Vietnam; Molecular Diagnostics Section, The NK-BIOTEK Laboratory, Ho Chi Minh City, Vietnam; Department of Pathology, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Abe
authors.affiliation: Department of Pathology and Laboratory Medicine, Center for Viral Oncology, University of Kansas Medical Center, MS 3046, 3901 Rainbow Boulevard, Kansas City, KS 66160, United States of America. Electronic address: llu@kumc.edu.
authors.forename: Ling
authors.initials: L
authors.lastname: Lu
mesh_terms: D016679:Genome, Viral; D005838:Genotype; D016174:Hepacivirus / Q000235:genetics*; D006526:Hepatitis C / Q000453:epidemiology / Q000821:virology*; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D014744:Vietnam / Q000453:epidemiology
keywords: Full-length genome; Genotype 6; HCV; Sequence