title: Systematic review of various laser intervention strategies for proliferative diabetic retinopathy.
abstract: Diabetic retinopathy (DR) is a common complication of diabetes. DR obstructs blood supply to the retina and has serious and long-lasting detrimental effects on quality of life. Panretinal photocoagulation, a laser surgical intervention, is advocated for early treatment of DR to prevent visual loss; however, results from studies reporting its efficacy vary markedly. In this review, we systematically conducted a database search of randomized controlled trials that investigated the safety and efficacy of different types of laser interventions, alone or in combination with adjunct intravitreal steroid utilization, in patients with DR. Data from 14 studies demonstrated that panretinal photocoagulation can be a safe and effective option for reducing visual loss and blindness in patients with DR.
authors.affiliation: Department of Ophthalmology, Shanghai First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200080, China.
authors.forename: Dawei
authors.initials: D
authors.lastname: Luo
authors.forename: Zhi
authors.initials: Z
authors.lastname: Zheng
authors.forename: Xun
authors.initials: X
authors.lastname: Xu
authors.forename: Ying
authors.initials: Y
authors.lastname: Fan
authors.forename: Bijun
authors.initials: B
authors.lastname: Zhu
authors.forename: Kun
authors.initials: K
authors.lastname: Liu
authors.forename: Fenghua
authors.initials: F
authors.lastname: Wang
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Sun
authors.forename: Haidong
authors.initials: H
authors.lastname: Zou
authors.forename: Xin
authors.initials: X
authors.lastname: Xia
mesh_terms: D016208:Databases, Factual; D003930:Diabetic Retinopathy / Q000601:surgery*; D006801:Humans; D017075:Laser Coagulation / Q000295:instrumentation* / Q000379:methods*; D016032:Randomized Controlled Trials as Topic
keywords: diabetes; diabetic retinopathy; panretinal photocoagulation; systematic review