title: Clinical efficacy of endoscopic pancreatic drainage for pain relief with malignant pancreatic duct obstruction.
abstract: OBJECTIVE
  This study was conducted to investigate the efficacy of pancreatic drainage for pain relief in advanced pancreatic cancer.
  
  
  METHODS
  Seventy-one patients with pancreatic carcinoma were divided into two groups: dilated and non-dilated pancreatic ducts. All patients underwent endoscopic retrograde cholangiopancreatography (ERCP), endoscopic biliary stenting and pancreatic stenting. Visual Analog Scale (VAS) scores, pain remission rates and survival time were evaluated during follow-up.
  
  
  RESULTS
  The post-ERCP VAS score of the dilated group was lower than that of the non-dilated group at 1 and 3 months post-ERCP. There was no difference at 6 months. The pain remission rate in the dilated duct group was significantly higher than that in non-dilated duct group in 1 and 3 months post-ERCP. The median survival times were 8.17 and 8.22 months respectively.
  
  
  CONCLUSIONS
  Endoscopic pancreatic drainage can relieve pain of advanced pancreatic cancer accompanied by safe dilation of the pancreatic duct.
authors.affiliation: Department of endoscope, the General Hospital of Shenyang Military Region, Shenyang 110016, China E-mail : soar_gaofei@126.com, soar1999@163.com.
authors.forename: Fei
authors.initials: F
authors.lastname: Gao
authors.forename: Shuren
authors.initials: S
authors.lastname: Ma
authors.forename: Ning
authors.initials: N
authors.lastname: Zhang
authors.forename: Yingchun
authors.initials: Y
authors.lastname: Zhang
authors.forename: Meina
authors.initials: M
authors.lastname: Ai
authors.forename: Bing
authors.initials: B
authors.lastname: Wang
mesh_terms: D015746:Abdominal Pain / Q000601:surgery; D000368:Aged; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000379:methods*; D004322:Drainage / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D059408:Pain Management / Q000379:methods*; D010183:Pancreatic Ducts / Q000601:surgery*; D010190:Pancreatic Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D011446:Prospective Studies; D015607:Stents; D016896:Treatment Outcome