title: Fluoride retention in saliva and in dental biofilm after different home-use fluoride treatments.
abstract: This single-blind, randomized, crossover study aimed at assessing the long-term fluoride concentrations in saliva and in dental biofilm after different home-use fluoride treatments. The study volunteers (n = 38) were residents of an area with fluoridated drinking water. They were administered four treatments, each of which lasted for one week: twice-daily placebo dentifrice, twice-daily fluoride dentifrice, twice-daily fluoride dentifrice and once-daily fluoride mouthrinse, and thrice-daily fluoride dentifrice. At the end of each treatment period, samples of unstimulated saliva and dental biofilm were collected 8 h after the last oral hygiene procedure. Fluoride concentrations in saliva and dental biofilm were analyzed using a specific electrode. The fluoride concentrations in saliva and dental biofilm 8 h after the last use of fluoride products did not differ among treatments. The results of this study suggest that treatments with home-use fluoride products have no long-term effect on fluoride concentrations in saliva and in dental biofilm of residents of an area with a fluoridated water supply.
authors.affiliation: Department of Preventive and Social Dentistry, Faculty of Dentistry, Universidade Federal do Rio Grande do Sul ? UFRGS, Porto Alegre, RS, Brazil.
authors.forename: Daniela Correia Cavalcante
authors.initials: DC
authors.lastname: Souza
authors.affiliation: Department of Preventive and Social Dentistry, Faculty of Dentistry, Universidade Federal do Rio Grande do Sul ? UFRGS, Porto Alegre, RS, Brazil.
authors.forename: Marisa
authors.initials: M
authors.lastname: Maltz
authors.affiliation: Department of Preventive and Social Dentistry, Faculty of Dentistry, Universidade Federal do Rio Grande do Sul ? UFRGS, Porto Alegre, RS, Brazil.
authors.forename: Lina Naomi
authors.initials: LN
authors.lastname: Hashizume
mesh_terms: D000328:Adult; D018441:Biofilms / Q000187:drug effects*; D002327:Cariostatic Agents / Q000032:analysis* / Q000627:therapeutic use*; D018592:Cross-Over Studies; D003773:Dental Plaque / Q000737:chemistry; D003802:Dentifrices / Q000737:chemistry / Q000627:therapeutic use; D005260:Female; D005457:Fluoridation; D005459:Fluorides / Q000032:analysis* / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009067:Mouthwashes / Q000737:chemistry / Q000627:therapeutic use; D011897:Random Allocation; D012463:Saliva / Q000737:chemistry / Q000187:drug effects*; D016037:Single-Blind Method; D018709:Statistics, Nonparametric; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D002327:Cariostatic Agents; D003802:Dentifrices; D009067:Mouthwashes; D005459:Fluorides