title: De novo amyloidosis in a renal transplant patient.
abstract: Systemic AA amyloidosis is a serious complication of many chronic inflammatory disorders and chronic infections. Renal involvement is seen in the majority of the patients and can lead to end-stage renal disease. Renal transplantation can be performed in these patients; however, amyloidosis can recur in the transplanted kidneys. On the other hand, de novo AA amyloidosis in renal transplant patients has been rarely reported. We report a 17-yr-old patient with end-stage renal disease due to genitourinary anomalies who developed recurrent pyelonephritis after transplantation. Three yr after transplantation, renal biopsy was performed for proteinuria and AA amyloidosis was identified in the renal allograft. Although rare, chronic infections might cause de novo amyloidosis in renal transplant patients. Therefore, amyloidosis should be kept in mind in those types of patients who present with proteinuria.
authors.affiliation: Department of Pediatric Nephrology, Ankara University School of Medicine, Ankara, Turkey.
authors.forename: Songül
authors.initials: S
authors.lastname: Yılmaz
authors.forename: Z Birsin
authors.initials: ZB
authors.lastname: Özçakar
authors.forename: Burcu
authors.initials: B
authors.lastname: Bulum
authors.forename: Saba
authors.initials: S
authors.lastname: Kiremitçi
authors.forename: Arzu
authors.initials: A
authors.lastname: Ensari
authors.forename: Mesiha
authors.initials: M
authors.lastname: Ekim
authors.forename: Kenan
authors.initials: K
authors.lastname: Keven
authors.forename: Fatoş
authors.initials: F
authors.lastname: Yalçınkaya
mesh_terms: D000293:Adolescent; D000686:Amyloidosis / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007674:Kidney Diseases / Q000175:diagnosis / Q000209:etiology*; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation; D008297:Male; D011183:Postoperative Complications / Q000175:diagnosis
keywords: AA amyloidosis; denovo; kidney transplant; proteinuria; renal allograft