title: Splenic metastasis of squamous cell carcinoma of the uterine cervix: a case report and review of the literature.
abstract: Metastasis from various neoplasms to the spleen is very rare and most of the cases are found at autopsy. We report a patient presenting with uterine cervical cancer with splenic metastases. A 49-year-old woman presenting with genital bleeding was referred to our hospital and diagnosed with stage IIB cervical cancer. She underwent concomitant chemoradiotherapy (CCRT) consisting of 50 Gy whole pelvis irradiation, high-dose-rate intracavitary brachytherapy 24 Gy/4 fractions and six weeks of paclitaxel and carboplatin administration. Ten months after the initial therapy, CT revealed recurrence at spleen. Although she received 5 courses of nedaplatin, enlargement of the tumor was noticed. She underwent a splenectomy and the result of histology was compatible with metastasis of cervical cancer.
authors.affiliation: Department of Obstetrics and Gynecology, National Hospital Organization Fukuyama Medical Center, Okinogamicho 4-14-17, Fukuyama, Hiroshima Prefecture 0825-720, Japan.
authors.forename: Shigeki
authors.initials: S
authors.lastname: Taga
authors.affiliation: Department of Obstetrics and Gynecology, National Hospital Organization Fukuyama Medical Center, Okinogamicho 4-14-17, Fukuyama, Hiroshima Prefecture 0825-720, Japan.
authors.forename: Mari
authors.initials: M
authors.lastname: Sawada
authors.affiliation: Department of Obstetrics and Gynecology, National Hospital Organization Fukuyama Medical Center, Okinogamicho 4-14-17, Fukuyama, Hiroshima Prefecture 0825-720, Japan.
authors.forename: Aya
authors.initials: A
authors.lastname: Nagai
authors.affiliation: Department of Obstetrics and Gynecology, National Hospital Organization Fukuyama Medical Center, Okinogamicho 4-14-17, Fukuyama, Hiroshima Prefecture 0825-720, Japan.
authors.forename: Dan
authors.initials: D
authors.lastname: Yamamoto
authors.affiliation: Department of Obstetrics and Gynecology, National Hospital Organization Fukuyama Medical Center, Okinogamicho 4-14-17, Fukuyama, Hiroshima Prefecture 0825-720, Japan.
authors.forename: Ryoji
authors.initials: R
authors.lastname: Hayase