title: Granulocytic sarcoma with compressive myelopathy: a rare presentation of chronic myelogenous leukemia.
abstract: Granulocytic sarcoma occurs most commonly in acute myelogenous leukemia. The appearance of granulocytic sarcoma in chronic myelogenous leukemia signals accelerated phase/ blast transformation. This is a rare case of undiagnosed chronic myelogenous leukemia with granulocytic sarcoma causing cord compression, which went into tumour lysis syndrome requiring dialysis after starting of steroids and radiotherapy. A 43-year-old male presented in emergency department with acute onset of flaccid paralysis. On clinical examination, there was hepatosplenomegaly and lower motor neuron paralysis in the lower limbs. The peripheral smear was consistent with chronic myelogenous leukemia in chronic phase. The MRI spine revealed para-spinal and epidural masses causing cord compression and the biopsy from the paraspinal mass was consistent with granulocytic sarcoma.
authors.affiliation: Assistant Professor, Department of Haematology, Christian Medical College and Hospital , Vellore, Tamil Nadu, India .
authors.forename: Abhijeet P
authors.initials: AP
authors.lastname: Ganapule
authors.affiliation: Professor, Department of Haematology, Christian Medical College and Hospital , Vellore, Tamil Nadu, India .
authors.forename: Auro
authors.initials: A
authors.lastname: Viswabandya
authors.affiliation: Assistant Professor, Department of Radiology, Christian Medical College and Hospital , Vellore, Tamil Nadu, India .
authors.forename: Anita
authors.initials: A
authors.lastname: Jasper
authors.affiliation: Assistant Professor, Department of Pathology, Christian Medical College and Hospital , Vellore, Tamil Nadu, India .
authors.forename: Palak
authors.initials: P
authors.lastname: Patel
authors.affiliation: Fellow In Haematopathology, Department of Pathology, Christian Medical College and Hospital , Vellore, Tamil Nadu, India .
authors.forename: Gautami
authors.initials: G
authors.lastname: Kokil
keywords: Cord compression; Granulocytic sarcoma; Tumour lysis syndrome