title: Alkaloids from the tribe Bocconieae (papaveraceae): a chemical and biological review.
abstract: The Bocconieae tribe, consisting of only the genera Macleaya and Bocconia, possesses significant economic and medicinal value and plays an important role in health management for people in developing countries. During the past decades, research on metabolites and relative pharmacology, including the isolation and identification of a variety of molecules, has shed light on the tribe. Among those molecules, isoquinoline alkaloids, and their antimicrobial, antifungal, and anti-inflammatory activities are especially noteworthy. This paper presents a comprehensive compilation of current research progress, with emphasis on the alkaloids and their distribution, phytochemical and pharmacological investigation, toxicity and side effects, related chemotaxonomy and future use prospects, and hopefully provides a valuable reference as an effort to promote further exploration and application of this tribe.
authors.affiliation: Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
authors.forename: Xuelong
authors.initials: X
authors.lastname: Yu
authors.affiliation: Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Gao
authors.affiliation: Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
authors.forename: Zhixiang
authors.initials: Z
authors.lastname: Zhu
authors.affiliation: Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Cao
authors.affiliation: Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China. pengfeitu@vip.163.com.
authors.forename: Pengfei
authors.initials: P
authors.lastname: Tu
authors.affiliation: Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China. xingyunchai@yeah.net.
authors.forename: Xingyun
authors.initials: X
authors.lastname: Chai
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000627:therapeutic use*; D000890:Anti-Infective Agents / Q000737:chemistry / Q000627:therapeutic use; D000935:Antifungal Agents / Q000737:chemistry; D006801:Humans; D007546:Isoquinolines / Q000737:chemistry*; D008519:Medicine, Traditional; D028101:Papaveraceae / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D007546:Isoquinolines; C039109:isoquinoline