title: Uveal melanoma gene expression profile test result provided for uveal metastasis.
abstract: The DecisionDx-UM gene expression profiling test is an accurate, popular, and technically simple method for obtaining prognostic information from uveal melanoma tissue. However, this test does not provide diagnostic information and may errantly provide prognostication results for lesions other than uveal melanoma. A 73-year-old woman presented with a uveal metastasis from lung adenocarcinoma, which was misdiagnosed as uveal melanoma. DecisionDx-UM gene expression profiling was performed on tissue obtained from a needle biopsy. A test result was provided regarding the lesion's metastatic potential even though it was not a uveal melanoma.
authors.forename: Michael I
authors.initials: MI
authors.lastname: Seider
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Stewart
authors.forename: Kavita K
authors.initials: KK
authors.lastname: Mishra
authors.forename: Bertil E
authors.initials: BE
authors.lastname: Damato
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics / Q000378:metabolism / Q000556:secondary*; D000077192:Adenocarcinoma of Lung; D000368:Aged; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D052138:Genes, Neoplasm; D005821:Genetic Techniques; D006801:Humans; D008175:Lung Neoplasms / Q000235:genetics / Q000378:metabolism / Q000556:secondary*; D008545:Melanoma / Q000235:genetics* / Q000378:metabolism; D009362:Neoplasm Metastasis; D014604:Uveal Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000378:metabolism / Q000556:secondary; D000098943:Uveal Melanoma