title: Comparison of associative recognition versus source recognition.
abstract: The importance of the medial temporal lobe (MTL) for memory of arbitrary associations has been well established. However, the contribution of the MTL in concurrent retrieval of different classes of associations remains unclear. The present fMRI study investigated neural correlates of concurrent retrieval of associative and source memories. Participants studied a list of object pairs with two study tasks and judged the status and context of the pair during test. Associative retrieval was supported by neural activity in bilateral prefrontal cortex and left ventral occipito-temporal cortex, while source recognition was linked to activity in the right caudate. Both the hippocampus and MTL cortex showed retrieval activity for associative and source memory. Importantly, greater brain activity for successful associative recognition accompanied with successful source recognition was evident in left perirhinal and anterior hippocampal regions. These results indicate that the MTL is critical in the retrieval of different classes of associations.
authors.affiliation: University of Texas at Arlington, United States. Electronic address: hkpark@uta.edu.
authors.forename: Heekyeong
authors.initials: H
authors.lastname: Park
authors.affiliation: University of Texas at Arlington, United States.
authors.forename: Cheryl
authors.initials: C
authors.lastname: Abellanoza
authors.affiliation: University of Texas at Arlington, United States.
authors.forename: James D
authors.initials: JD
authors.lastname: Schaeffer
mesh_terms: D000293:Adolescent; D000328:Adult; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D021641:Recognition, Psychology / Q000502:physiology*; D013702:Temporal Lobe / Q000502:physiology*; D055815:Young Adult
keywords: Associative memory; Hippocampus; MTL; Source memory; fMRI