title: [Clinical evaluation of six patients with anti-NMDAR encephalitis].
abstract: OBJECTIVE
  We examined the clinical course and the prognosis of patients with anti-NMDAR encephalitis.
  
  
  METHODS
  We retrospectively evaluated the patients who has distinctive clinical features as anti-NMDAR encephalitis based on their medical records.
  
  
  RESULTS
  There were two male and four female patients with anti-NMDAR encephalitis. They were aged between 13 and 16 years. One of the six, 14 years female patient was negative for anti-NMDAR antibody. All four female patients with anti-NMDAR encephalitis had an ovarian tumor. Neurocognitive dysfunction and epilepsy remained in one female patient with right temporal lobe lesion and one male patient with celebellar abnormalities had mild mental impairment. In three patients including two patients who were examined abdominal MRI for the first time after recovery from the encephalitis, overian tumors became apparent during follow-up. In one of other patients, overian tumors had a tendency to increase in size after recovery.
  
  
  CONCLUSIONS
  Sequellae were seen in two cases that have abnormalities in brain MRI. As to ovarian tumor, it was considered to be necessary to checkup pelvic MRI for at least four years after the onset of encephalitis.
authors.forename: Asako
authors.initials: A
authors.lastname: Horino
authors.forename: Masashi
authors.initials: M
authors.lastname: Shiomi
authors.forename: Takeshi
authors.initials: T
authors.lastname: Inoue
authors.forename: Megumi
authors.initials: M
authors.lastname: Nukui
authors.forename: Ichiro
authors.initials: I
authors.lastname: Kuki
authors.forename: Shin
authors.initials: S
authors.lastname: Okazaki
authors.forename: Hisashi
authors.initials: H
authors.lastname: Kawawaki
authors.forename: Kiyoko
authors.initials: K
authors.lastname: Amo
authors.forename: Masao
authors.initials: M
authors.lastname: Togawa
mesh_terms: D000293:Adolescent; D060426:Anti-N-Methyl-D-Aspartate Receptor Encephalitis / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000628:therapy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012189:Retrospective Studies