title: Antiretroviral therapy: treatment-experienced individuals.
abstract: Antiretroviral therapy (ART)-experienced individuals may choose to modify their regimens because of suboptimal virologic response, poor tolerability, convenience, or to minimize interactions with other medications or food. Constructing a new regimen for any of these reasons requires a thorough review of prior antiretroviral drug use and available drug resistance results. This article summarizes the strategies used in managing the ART-experienced individual who is considering a modification in therapy at the time of suboptimal virologic response or while virologically suppressed on a stable regimen.
authors.affiliation: Division of HIV Medicine, Department of Internal Medicine, Harbor-UCLA Medical Center, David Geffen School of Medicine at UCLA, 1124 West Carson Street, CDCRC 203, Torrance, CA 90502, USA.
authors.forename: Katya R
authors.initials: KR
authors.lastname: Calvo
authors.affiliation: Division of HIV Medicine, Department of Internal Medicine, Harbor-UCLA Medical Center, David Geffen School of Medicine at UCLA, 1124 West Carson Street, CDCRC 205, Torrance, CA 90502, USA. Electronic address: edaar@labiomed.org.
authors.forename: Eric S
authors.initials: ES
authors.lastname: Daar
mesh_terms: D044966:Anti-Retroviral Agents / Q000008:administration & dosage*; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods*; D024882:Drug Resistance, Viral; D006678:HIV / Q000187:drug effects*; D015658:HIV Infections / Q000188:drug therapy* / Q000821:virology; D006801:Humans; D055118:Medication Adherence; D008826:Microbial Sensitivity Tests; D017211:Treatment Failure
chemical_list: D044966:Anti-Retroviral Agents
keywords: Antiretroviral failure; HIV resistance; Treatment experienced; Treatment simplification