title: Autologous clavicle bone graft for anterior cervical discectomy and fusion with titanium interbody cage.
abstract: A variety of donor-site complications have been reported for anterior cervical discectomy and fusion (ACDF) using autologous iliac bone graft. To minimize such morbidities and to obtain optimal bony fusion at the ACDF surgery, a novel technique was used to harvest cancellous bone from the autologous clavicle instead of the popular iliac crest graft. After a routine cervical discectomy of the affected level, a 1.5-cm linear skin incision was made over the clavicle within 2.5 cm of the sternoclavicular joint on the medial one-third portion. This portion is known as an anatomically safe zone, with no subcutaneous distribution of the supraclavicular nerve. Then, cancellous bone was harvested through a small cortical window developed on the clavicle. Care was taken not to injure the subclavian major vessels and the lung below the clavicle. A box-type titanium cage was packed with the harvested cancellous bone and then inserted into the discectomy-treated space for cervical interbody fusion. From 2009 to 2013, 16 patients with cervical radiculopathy and/or myelopathy underwent single-level ACDF with this method. All but 1 patient experienced significant improvement of clinical symptoms after the surgery and showed radiographic evidence of solid bony fusion and spinal stabilization within 6 months. Further, no peri- and postoperative complications at the clavicular donor site were noted. The mean visual analog scale pain score (range 0 [no pain to 10 [maximum pain]) at 1 year after the surgery was 0.1, and 13 of 14 patients with data at 1-year follow-up were highly satisfied with their donor-site cosmetic outcome. The clavicle is a safe, reliable, and technically easy source of autologous bone graft that yields optimal fusion rates and patient satisfaction with ACDF surgery.
authors.affiliation: Department of Neurosurgery, Kitano Medical Research Institute and Hospital, Osaka; and.
authors.forename: Koichi
authors.initials: K
authors.lastname: Iwasaki
authors.forename: Taichi
authors.initials: T
authors.lastname: Ikedo
authors.forename: Hirokuni
authors.initials: H
authors.lastname: Hashikata
authors.forename: Hiroki
authors.initials: H
authors.lastname: Toda
mesh_terms: D000328:Adult; D000368:Aged; D002574:Cervical Vertebrae / Q000601:surgery*; D002968:Clavicle / Q000637:transplantation*; D003952:Diagnostic Imaging; D017586:Diskectomy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013123:Spinal Fusion / Q000295:instrumentation / Q000379:methods*; D011795:Surveys and Questionnaires; D020858:Tissue and Organ Harvesting / Q000379:methods*; D014025:Titanium; D014182:Transplantation, Autologous; D016896:Treatment Outcome
chemical_list: D014025:Titanium
keywords: ACDF = anterior cervical discectomy and fusion; VAS = visual analog scale; anterior cervical discectomy and fusion; autologous bone graft; clavicle; donor-site complications; iliac crest; technique; titanium cage