title: Deep brain stimulation in the treatment of Holmes tremor - a long-term case observation.
abstract: We present the patient with Holmes tremor secondary to the infarction of thalamus, successfully treated with the deep brain stimulation (DBS) of the area between ventralis oralis anterior and zona incerta for a long time, in whom the severe tremor reappeared after removal of the DBS lead. This is the first presentation of the effective DBS on this location. Our case does not support the hypothesis that the DBS treatment could lead to sustained relief of symptoms after cessation of stimulation.
authors.affiliation: Department of Neurology, Jagiellonian University Medical College, Krakow, Poland. Electronic address: nath87@wp.pl.
authors.forename: Natalia
authors.initials: N
authors.lastname: Grabska
authors.affiliation: Department of Neurology, Medical University of Silesia, Katowice, Poland.
authors.forename: Monika
authors.initials: M
authors.lastname: Rudzińska
authors.affiliation: Department of Neurology, Jagiellonian University Medical College, Krakow, Poland.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Dec-Ćwiek
authors.affiliation: Medtronic, Poland.
authors.forename: Marcin
authors.initials: M
authors.lastname: Tutaj
authors.affiliation: Department of Neurosurgery, Jagiellonian University Medical College, Poland.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Pietraszko
authors.affiliation: Department of Neurology, Jagiellonian University Medical College, Krakow, Poland.
authors.forename: Michał
authors.initials: M
authors.lastname: Michalski
authors.affiliation: Department of Neurology, Jagiellonian University Medical College, Krakow, Poland.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Szczudlik
mesh_terms: D020520:Brain Infarction / Q000628:therapy*; D046690:Deep Brain Stimulation / Q000379:methods*; D005260:Female; D006801:Humans; D008875:Middle Aged; D020530:Subthalamus; D013786:Thalamic Diseases / Q000628:therapy*; D016896:Treatment Outcome; D014202:Tremor / Q000628:therapy*
keywords: Deep brain stimulation; Holmes tremor; Ventralis oralis anterior; Zona incerta