title: Trichilemmal carcinoma - a rare cutaneous malignancy: report of two cases.
abstract: The trichilemmal carcinoma is a rare low-grade malignant lesion originating from hair follicle cells that usually occurs on sun-exposed skin of older individuals. A differential diagnostic is required with other skin carcinomas. We report two cases of trichilemmal carcinoma admitted at the Emergency University Hospital of Bucharest, Romania, in 2012, one of these cases being localized in the periocular area and the other one resembling a cutaneous horn. These cases present several unusual aspects that are rarely described in the literature namely the site of the tumor which in the eyelid, development of a cutaneous horn, IHC tests which revealed EMA (epithelial membrane antigen) positivity in tumor cells. Considering that this type of tumor seldom develops metastases or local recurrences, and all the cases had free margins, there was no adjuvant therapy.
authors.affiliation: Department of Pathology, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania; m_costache_dermatopat@yahoo.com.
authors.forename: Maria
authors.initials: M
authors.lastname: Sajin
authors.forename: Mihaela Cristina
authors.initials: MC
authors.lastname: Luchian
authors.forename: Alina
authors.initials: A
authors.lastname: Hodorogea Prisăcaru
authors.forename: Adrian
authors.initials: A
authors.lastname: Dumitru
authors.forename: Oana Maria
authors.initials: OM
authors.lastname: Pătraşcu
authors.forename: Diana
authors.initials: D
authors.lastname: Costache
authors.forename: Doina
authors.initials: D
authors.lastname: Dumitrescu
authors.forename: Ana Maria
authors.initials: AM
authors.lastname: Oproiu
authors.forename: Olga
authors.initials: O
authors.lastname: Simionescu
authors.forename: Mariana
authors.initials: M
authors.lastname: Costache
mesh_terms: D000369:Aged, 80 and over; D002467:Cell Nucleus / Q000473:pathology; D005260:Female; D018859:Hair Follicle / Q000473:pathology*; D006801:Humans; D012878:Skin Neoplasms / Q000473:pathology*