title: [Glucocorticoid and Bone. Efficacy of active vitamin D on glucocorticoid-induced osteoporosis].
abstract: Active vitamin D is a second line treatment followed by bisphosphonate in the Japanese guideline of glucocorticoid-induced osteoporosis (GIO) . Although it shows relatively mild but significant effect on BMD and fracture prevention, it is utilized as combination therapy with bisphosphonate. Vitamin D is recommended for GIO with gastrointestinal disease and hepatobiliary disorders. Vitamin D may be the first line treatment for younger GIO patients.
authors.affiliation: Izumiotsu Manicipal Hospital, Japan.
authors.forename: Takami
authors.initials: T
authors.lastname: Miki
authors.forename: Keiji
authors.initials: K
authors.lastname: Okamoto
mesh_terms: D000818:Animals; D015519:Bone Density / Q000187:drug effects; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D001842:Bone and Bones / Q000187:drug effects* / Q000378:metabolism; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D010024:Osteoporosis / Q000139:chemically induced / Q000188:drug therapy*; D014807:Vitamin D / Q000378:metabolism / Q000627:therapeutic use*
chemical_list: D050071:Bone Density Conservation Agents; D005938:Glucocorticoids; D014807:Vitamin D