title: Cyclometalated gold(III) complexes for chemoselective cysteine modification via ligand controlled C-S bond-forming reductive elimination.
abstract: Modular assembly of cyclometalated gold(III) complexes by choosing appropriate bidentate C,N-donor ligands and ancillary ligands for chemoselective cysteine modification of peptides and proteins via C-S bond-forming reductive elimination has been achieved.
authors.affiliation: State Key Laboratory of Chirosciences and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China. mankin.wong@polyu.edu.hk thomas.yun-chung.leung@polyu.edu.hk.
authors.forename: Karen Ka-Yan
authors.initials: KK
authors.lastname: Kung
authors.forename: Hok-Ming
authors.initials: HM
authors.lastname: Ko
authors.forename: Jian-Fang
authors.initials: JF
authors.lastname: Cui
authors.forename: Hiu-Chi
authors.initials: HC
authors.lastname: Chong
authors.forename: Yun-Chung
authors.initials: YC
authors.lastname: Leung
authors.forename: Man-Kin
authors.initials: MK
authors.lastname: Wong
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002417:Cattle; D003545:Cysteine / Q000737:chemistry*; D006801:Humans; D008024:Ligands; D008958:Models, Molecular; D008969:Molecular Sequence Data; D050607:Organogold Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D010455:Peptides / Q000737:chemistry*; D012709:Serum Albumin / Q000737:chemistry*; D012710:Serum Albumin, Bovine / Q000737:chemistry*
chemical_list: D008024:Ligands; D050607:Organogold Compounds; D010455:Peptides; D012709:Serum Albumin; D012710:Serum Albumin, Bovine; D003545:Cysteine