title: Absorbed radiation dose in radiosensitive organs using 64- and 320-row multidetector computed tomography: a comparative study.
abstract: Aim. To determine absorbed radiation dose (ARD) in radiosensitive organs during prospective and full phase dose modulation using ECG-gated MDCTA scanner under 64- and 320-row detector modes. Methods. Female phantom was used to measure organ radiation dose. Five DP-3 radiation detectors were used to measure ARD to lungs, breast, and thyroid using the Aquilion ONE scanner in 64- and 320-row modes using both prospective and dose modulation in full phase acquisition. Five measurements were made using three tube voltages: 100, 120, and 135 kVp at 400 mA at heart rate (HR) of 60 and 75 bpm for each protocol. Mean acquisition was recorded in milligrays (mGy). Results. Mean ARD was less for 320-row versus 64-row mode for each imaging protocol. Prospective EKG-gated imaging protocol resulted in a statistically lower ARD using 320-row versus 64-row modes for midbreast (6.728 versus 19.687 mGy, P < 0.001), lung (6.102 versus 21.841 mGy, P < 0.001), and thyroid gland (0.208 versus 0.913 mGy; P < 0.001). Retrospective imaging using 320- versus 64-row modes showed lower ARD for midbreast (10.839 versus 43.169 mGy, P < 0.001), lung (8.848 versus 47.877 mGy, P < 0.001), and thyroid gland (0.057 versus 2.091 mGy; P < 0.001). ARD reduction was observed at lower kVp and heart rate. Conclusions. Dose reduction to radiosensitive organs is achieved using 320-row compared to 64-row modes for both prospective and retrospective gating, whereas 64-row mode is equivalent to the same model 64-row MDCT scanner.
authors.affiliation: Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
authors.forename: Atif N
authors.initials: AN
authors.lastname: Khan
authors.affiliation: Department of Radiology and Imaging Sciences, Emory University Hospital, Atlanta, GA 30308, USA.
authors.forename: Waqas
authors.identifier: 0000-0002-3366-2700
authors.initials: W
authors.lastname: Shuaib
authors.affiliation: Department of Radiology, Albert Einstein Medical Center, Philadelphia, PA 19141, USA.
authors.forename: Boris
authors.initials: B
authors.lastname: Nikolic
authors.affiliation: Department of Radiology and Imaging Sciences, Emory University Hospital, Atlanta, GA 30308, USA.
authors.forename: Mohammad K
authors.initials: MK
authors.lastname: Khan
authors.affiliation: Department of Radiology and Imaging Sciences, Emory University Hospital, Atlanta, GA 30308, USA.
authors.forename: Jian
authors.initials: J
authors.lastname: Kang
authors.affiliation: Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA ; Department of Radiology and Imaging Sciences, Emory University Hospital, Atlanta, GA 30308, USA.
authors.forename: Faisal
authors.initials: F
authors.lastname: Khosa