title: Estimating absolute aortic pressure using MRI and a one-dimensional model.
abstract: Aortic blood pressure is a strong indicator to cardiovascular diseases and morbidity. Clinically, pressure measurements are done by inserting a catheter in the aorta. However, imaging techniques have been used to avoid the invasive procedure of catheterization. In this paper, we combined MRI measurements to a one-dimensional model in order to simulate blood flow in an aortic segment. Absolute pressure was estimated in the aorta by using MRI measured flow as boundary conditions and MRI measured compliance as a pressure law for solving the model. Model computed pressure was compared to catheter measured pressure in an aortic phantom. Furthermore, aortic pressure was estimated in vivo in three healthy volunteers.
authors.affiliation: Imagerie par Résonance Magnétique Médicale et Multi-Modalités (IR4M), Université Paris-Sud - CNRS, UMR 8081, Orsay, France. Electronic address: mayakhal@gmail.com.
authors.forename: Maya
authors.initials: M
authors.lastname: Khalifé
authors.affiliation: Laboratoire de Mathématiques d׳Orsay, Université Paris-Sud - CNRS, UMR 8628, Orsay, France.
authors.forename: Astrid
authors.initials: A
authors.lastname: Decoene
authors.affiliation: Laboratoire de Mathématiques d׳Orsay, Université Paris-Sud - CNRS, UMR 8628, Orsay, France.
authors.forename: Filipa
authors.initials: F
authors.lastname: Caetano
authors.affiliation: Imagerie par Résonance Magnétique Médicale et Multi-Modalités (IR4M), Université Paris-Sud - CNRS, UMR 8081, Orsay, France.
authors.forename: Ludovic
authors.initials: L
authors.lastname: de Rochefort
authors.affiliation: Imagerie par Résonance Magnétique Médicale et Multi-Modalités (IR4M), Université Paris-Sud - CNRS, UMR 8081, Orsay, France.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Durand
authors.affiliation: Imagerie par Résonance Magnétique Médicale et Multi-Modalités (IR4M), Université Paris-Sud - CNRS, UMR 8081, Orsay, France.
authors.forename: Dima
authors.initials: D
authors.lastname: Rodríguez
mesh_terms: D000328:Adult; D001011:Aorta / Q000502:physiology*; D062186:Arterial Pressure; D001783:Blood Flow Velocity / Q000502:physiology; D002318:Cardiovascular Diseases / Q000503:physiopathology; D002404:Catheterization; D003187:Compliance; D006439:Hemodynamics; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008955:Models, Cardiovascular; D019047:Phantoms, Imaging
keywords: Aorta; Blood pressure; Cardiovascular imaging; Compliance; MRI; Non-invasive; One-dimensional model