title: Electronic processing of informed consents in a global pharmaceutical company environment.
abstract: We present an electronic capture tool to process informed consents, which are mandatory recorded when running a clinical trial. This tool aims at the extraction of information expressing the duration of the consent given by the patient to authorize the exploitation of biomarker-related information collected during clinical trials. The system integrates a language detection module (LDM) to route a document into the appropriate information extraction module (IEM). The IEM is based on language-specific sets of linguistic rules for the identification of relevant textual facts. The achieved accuracy of both the LDM and IEM is 99%. The architecture of the system is described in detail.
authors.affiliation: Division of Medical Information Sciences, University Hospitals and University of Geneva, Switzerland.
authors.forename: Dina
authors.initials: D
authors.lastname: Vishnyakova
authors.affiliation: BiTeM, HEG/University of Applied Sciences of Western Switzerland, Geneva Switzerland.
authors.forename: Julien
authors.initials: J
authors.lastname: Gobeill
authors.affiliation: Novartis Institute for BioMedical Research, Basel, Switzerland.
authors.forename: Fatma
authors.initials: F
authors.lastname: Oezdemir-Zaech
authors.affiliation: Novartis Institute for BioMedical Research, Basel, Switzerland.
authors.forename: Olivier
authors.initials: O
authors.lastname: Kreim
authors.affiliation: Novartis Institute for BioMedical Research, Basel, Switzerland.
authors.forename: Therese
authors.initials: T
authors.lastname: Vachon
authors.affiliation: Novartis Institute for BioMedical Research, Basel, Switzerland.
authors.forename: Thierry
authors.initials: T
authors.lastname: Clade
authors.affiliation: Novartis Institute for BioMedical Research, Basel, Switzerland.
authors.forename: Xavier
authors.initials: X
authors.lastname: Haenning
authors.affiliation: Novartis Institute for BioMedical Research, Basel, Switzerland.
authors.forename: Dmitri
authors.initials: D
authors.lastname: Mikhailov
authors.affiliation: BiTeM, HEG/University of Applied Sciences of Western Switzerland, Geneva Switzerland.
authors.forename: Patrick
authors.initials: P
authors.lastname: Ruch
mesh_terms: D001185:Artificial Intelligence; D002986:Clinical Trials as Topic / Q000331:legislation & jurisprudence / Q000706:statistics & numerical data*; D032962:Consent Forms / Q000145:classification* / Q000331:legislation & jurisprudence / Q000592:standards*; D003628:Database Management Systems; D016208:Databases, Factual; D004345:Drug Industry / Q000331:legislation & jurisprudence / Q000706:statistics & numerical data*; D016247:Information Storage and Retrieval / Q000379:methods*; D038622:Internationality; D009323:Natural Language Processing; D018875:Vocabulary, Controlled