title: Management of central nervous system teratoma.
abstract: Central nervous system (CNS) teratomas are very rare neoplasms that contain tissues derived from all three germ cell layers (endoderm, mesoderm, and ectoderm). Patients with teratomas usually have a good prognosis. Given the paucity of cases in the literature, we present a retrospective review of 15 CNS teratomas treated over a 25 year period at the University of California, San Francisco. We describe the presentation, location, treatment, and adjuvant therapy for these patients, and highlight three unique cases that emphasize the diverse presentation and treatment of these rare tumors.
authors.affiliation: Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Avenue, Box 0112, San Francisco, CA 94143-0112, USA. Electronic address: zygourakisc@neurosurg.ucsf.edu.
authors.forename: Corinna C
authors.initials: CC
authors.lastname: Zygourakis
authors.affiliation: Department of Pathology, University of California at San Francisco, San Francisco, CA, USA.
authors.forename: Jessica L
authors.initials: JL
authors.lastname: Davis
authors.affiliation: Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Avenue, Box 0112, San Francisco, CA 94143-0112, USA; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
authors.forename: Gurvinder
authors.initials: G
authors.lastname: Kaur
authors.affiliation: Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Avenue, Box 0112, San Francisco, CA 94143-0112, USA.
authors.forename: Christopher P
authors.initials: CP
authors.lastname: Ames
authors.affiliation: Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Avenue, Box 0112, San Francisco, CA 94143-0112, USA; Department of Pediatrics, University of California at San Francisco, San Francisco, CA, USA.
authors.forename: Nalin
authors.initials: N
authors.lastname: Gupta
authors.affiliation: Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Avenue, Box 0112, San Francisco, CA 94143-0112, USA; Department of Pediatrics, University of California at San Francisco, San Francisco, CA, USA.
authors.forename: Kurtis I
authors.initials: KI
authors.lastname: Auguste
authors.affiliation: Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Avenue, Box 0112, San Francisco, CA 94143-0112, USA; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
authors.forename: Andrew T
authors.initials: AT
authors.lastname: Parsa
mesh_terms: D000293:Adolescent; D000328:Adult; D016543:Central Nervous System Neoplasms / Q000175:diagnosis / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D019468:Disease Management; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013724:Teratoma / Q000175:diagnosis / Q000628:therapy*; D055815:Young Adult
keywords: Germ cell tumor; Intracranial; Spinal; Teratoma