title: [Accessibility of early infant diagnosis of HIV infection in Lome (Togo)].
abstract: BACKGROUND
  Early infant diagnosis of HIV is the key step for the early initiation of HAART among HIV-exposed children. The aim of this study was to estimate the proportion of children born to mothers infected with HIV who completed the early infant HIV diagnosis process and the factors associated with this complete process.
  
  
  METHODS
  We conducted a retrospective cohort study at Tokoin University Hospital in the pediatrics ward. This study included all HIV-exposed children born between July 2009 and June 2011. The association between the mother's, spouse's, and child's characteristics as well as access to early HIV diagnosis by PCR (blood collection and reporting of results before the 6months of age) was studied using logistic regression analysis.
  
  
  RESULTS
  A total of 455 HIV-exposed children were included: for 52.7%, the first test was PCR, 99 of them received their results, 59 of whom received their results before the 6th month of life (undergoing the complete process). In multivariate analysis, the only factor associated with the complete process of early HIV diagnosis was the maternal age≥28years (adjusted odds ratio, 1.75, 95% CI [1.18-2.76]).
  
  
  CONCLUSIONS
  The availability of early infant PCR diagnosis remains a challenge and innovative strategies must be implemented.
authors.affiliation: Service national de la nutrition, ministère de la Santé, 02 BP 20327, Lomé, Togo; Département des sciences fondamentales et santé publique, faculté des sciences de la santé, université de Lomé, BP 1515, Lomé, Togo.
authors.forename: M
authors.initials: M
authors.lastname: Bouraima
authors.affiliation: Département des sciences fondamentales et santé publique, faculté des sciences de la santé, université de Lomé, BP 1515, Lomé, Togo; Laboratoire de biologie moléculaire (BIOLIM), faculté des sciences de la santé, université de Lomé, BP 1515, Lomé, Togo.
authors.forename: M
authors.initials: M
authors.lastname: Salou
authors.affiliation: Programme PAC-CI, CHU de Treichville, 18 BP 1954, Abidjan 18, Côte d'Ivoire.
authors.forename: B K
authors.initials: BK
authors.lastname: Tchounga
authors.affiliation: Service de pédiatrie, CHU Sylvanus Olympio, BP 57, Lomé, Togo.
authors.forename: K
authors.initials: K
authors.lastname: Lawson-Evi
authors.affiliation: Service de pédiatrie, CHU Sylvanus Olympio, BP 57, Lomé, Togo.
authors.forename: D K
authors.initials: DK
authors.lastname: Kodjovi
authors.affiliation: Service de pédiatrie, CHU Sylvanus Olympio, BP 57, Lomé, Togo.
authors.forename: E
authors.initials: E
authors.lastname: Takassi
authors.affiliation: Département des sciences fondamentales et santé publique, faculté des sciences de la santé, université de Lomé, BP 1515, Lomé, Togo; Laboratoire de biologie moléculaire (BIOLIM), faculté des sciences de la santé, université de Lomé, BP 1515, Lomé, Togo.
authors.forename: C A
authors.initials: CA
authors.lastname: Dagnra
authors.affiliation: Département des sciences fondamentales et santé publique, faculté des sciences de la santé, université de Lomé, BP 1515, Lomé, Togo; Laboratoire de biologie moléculaire (BIOLIM), faculté des sciences de la santé, université de Lomé, BP 1515, Lomé, Togo.
authors.forename: M
authors.initials: M
authors.lastname: Prince-David
authors.affiliation: Programme national de lutte contre le sida, ministère de la Santé, 05 BP 424, Lomé 05, Togo; Service de dermatologie et IST, université de Lomé, CHU Sylvanus Olympio, BP 57, Lomé, Togo.
authors.forename: V P
authors.initials: VP
authors.lastname: Pitche
authors.affiliation: Département des sciences fondamentales et santé publique, faculté des sciences de la santé, université de Lomé, BP 1515, Lomé, Togo; Inserm, unité 897, 33076 Bordeaux cedex, France; Centre africain de recherche en épidémiologie et santé publique (CARESP), BP 4089, Lomé, Togo. Electronic address: didier.ekouevi@gmail.com.
authors.forename: D K
authors.initials: DK
authors.lastname: Ekouevi
mesh_terms: D000328:Adult; D015331:Cohort Studies; D042241:Early Diagnosis; D005260:Female; D006678:HIV / Q000235:genetics; D015658:HIV Infections / Q000097:blood / Q000175:diagnosis* / Q000635:transmission*; D006297:Health Services Accessibility; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D008423:Maternal Age; D015999:Multivariate Analysis; D016133:Polymerase Chain Reaction; D012189:Retrospective Studies; D014037:Togo