title: Clinical outcomes of the endoscopic submucosal dissection of early gastric cancer are comparable between absolute and new expanded criteria.
abstract: OBJECTIVE
  Advances in endoscopic submucosal dissection (ESD) techniques have led to the development of expanded criteria for endoscopic resection of early gas-tric cancer (EGC). The aim of this study was to evaluate the short- and long-term outcomes for ESD using indication cri-teria.
  
  
  METHODS
  A total of 1,105 patients underwent ESD for EGC at six medical centers. The patients were classified into the following two groups based on the lesion size, presence of ulceration and pathological review an absolute criteria group (n=517) and an expanded criteria group (n=588).
  
  
  RESULTS
  The curative resection rates (91.1% vs 91.3%, p=0.896) were similar in the absolute criteria group and the expanded criteria group. The en bloc resection rates (93.4% and 92.3%, respectively; p=0.488) and complete resection rates (98.3% and 97.4%, respectively; p=0.357) did not differ between the groups. The cumulative disease-free survival rates and the overall survival rates were similar between the groups (p=0.778 and p=0.654, respectively). Independent factors for the curative resection of EGC included tumor lo-cation (upper vs middle and lower, 2.632 [1.128-6.144] vs 3.497 [1.560-7.842], respectively) and en bloc resection rate 12.576 [7.442-21.250].
  
  
  CONCLUSIONS
  The expanded criteria for ESD in cases of EGC is comparable with the widely ac-cepted pre-existing criteria. (Gut Liver, 2015;9181-187).
authors.affiliation: Department of Internal Medicine, Kyungpook National University School of Medicine, Korea.
authors.forename: Keun Young
authors.initials: KY
authors.lastname: Shin
authors.affiliation: Department of Internal Medicine, Kyungpook National University School of Medicine, Korea.
authors.forename: Seong Woo
authors.initials: SW
authors.lastname: Jeon
authors.affiliation: Department of Internal Medicine, Keimyung University College of Medicine, Korea.
authors.forename: Kwang Bum
authors.initials: KB
authors.lastname: Cho
authors.affiliation: Department of Internal Medicine, Keimyung University College of Medicine, Korea.
authors.forename: Kyung Sik
authors.initials: KS
authors.lastname: Park
authors.affiliation: Department of Internal Medicine, Keimyung University College of Medicine, Korea.
authors.forename: Eun Soo
authors.initials: ES
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Fatima Hospital, Korea.
authors.forename: Chang Keun
authors.initials: CK
authors.lastname: Park
authors.affiliation: Department of Internal Medicine, Fatima Hospital, Korea.
authors.forename: Yun Jin
authors.initials: YJ
authors.lastname: Chung
authors.affiliation: Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea.
authors.forename: Joong Goo
authors.initials: JG
authors.lastname: Kwon
authors.affiliation: Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea.
authors.forename: Jin Tae
authors.initials: JT
authors.lastname: Jung
authors.affiliation: Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea.
authors.forename: Eun Young
authors.initials: EY
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Yeungnam University School of Medicine, Daegu, Korea.
authors.forename: Kyeong Ok
authors.initials: KO
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Yeungnam University School of Medicine, Daegu, Korea.
authors.forename: Byung Ik
authors.initials: BI
authors.lastname: Jang
authors.affiliation: Department of Internal Medicine, Yeungnam University School of Medicine, Daegu, Korea.
authors.forename: Si Hyung
authors.initials: SH
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Dongkuk University School of Medicine, Gyeongju, Korea.
authors.forename: Jeong Bae
authors.initials: JB
authors.lastname: Park
authors.affiliation: Department of Internal Medicine, Dongkuk University School of Medicine, Gyeongju, Korea.
authors.forename: Chang Hun
authors.initials: CH
authors.lastname: Yang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018572:Disease-Free Survival; D004210:Dissection / Q000379:methods*; D005260:Female; D005753:Gastric Mucosa / Q000601:surgery*; D005773:Gastroscopy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D066066:Response Evaluation Criteria in Solid Tumors; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery*; D015996:Survival Rate; D016896:Treatment Outcome
keywords: Criteria; Endoscopy, gastrointesti-nal; Stomach neoplasms