title: [Neuroprotective treatment of chronic cerebrovascular insufficiency].
abstract: OBJECTIVE
  To study the efficacy of cerebrolysin in 300 patients with chronic brain ischemia (CBI), I and II stages.
  
  
  METHODS
  The main group consisted of 195 patients with CBI, I stage and 105 patients with CBI, II stage. Patients of the control group (45 patients) did not receive cerebrolysin. Changes in neurological and emotional status, cognitive functions, indicators of platelet and erythrocyte aggregation, their deformity and morpho-densitometric parameters were studied.
  
  
  CONCLUSIONS
  Authors found the additional mechanisms of cerebrolysin action resulted in the improvement of morpho-densitometric characteristics of erythrocytes and hemorheological properties important for capillary blood flow.
authors.forename: A V
authors.initials: AV
authors.lastname: Anisimova
authors.forename: T I
authors.initials: TI
authors.lastname: Kolesnikova
authors.forename: E V
authors.initials: EV
authors.lastname: Iutskova
authors.forename: S S
authors.initials: SS
authors.lastname: Galkin
mesh_terms: D000328:Adult; D000596:Amino Acids / Q000627:therapeutic use*; D002545:Brain Ischemia / Q000097:blood / Q000188:drug therapy* / Q000523:psychology; D003071:Cognition / Q000187:drug effects; D019610:Cytoprotection; D004903:Erythrocyte Aggregation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018696:Neuroprotective Agents / Q000627:therapeutic use*
chemical_list: D000596:Amino Acids; D018696:Neuroprotective Agents; C006952:cerebrolysin