title: Subdural hematoma in diabetic patients.
abstract: OBJECTIVE
  Subdural hematoma (SDH) is associated with a high mortality rate. However, the risk of SDH in diabetic patients has not been well studied. The aim of the study was to examine the risk of SDH in incident diabetic patients.
  
  
  METHODS
  From a universal insurance claims database of Taiwan, a cohort of 28,045 incident diabetic patients from 2000 to 2005 and a control cohort of 56,090 subjects without diabetes were identified. The incidence and hazard ratio of SDH were measured by the end of 2010.
  
  
  RESULTS
  The mean follow-up years were 7.24 years in the diabetes cohort and 7.44 years in the non-diabetes cohort. The incidence of SDH was 1.57-fold higher in the diabetes cohort than in the non-diabetes cohort (2.04 vs. 1.30 per 1000 person-years), with an adjusted hazard ratio of 1.63 [95% confidence interval (CI) 1.43-1.85]. The stratified data showed that adjusted hazard ratios were 1.51 (95% CI 1.28-1.77) for traumatic SDH and 1.89 (95% CI 1.52-2.36) for non-traumatic SDH. The 30-day mortality rate for those who developed SDH in the diabetes cohort was 8.94%.
  
  
  CONCLUSIONS
  This study demonstrates that incident diabetic patients are at higher risk of SDH than individuals without diabetes. Proper intervention for diabetic patients is necessary for preventing the devastating disorder.
authors.affiliation: Graduate Institute of Clinical Medical Science, China Medical University College of Medicine, Taichung, Taiwan; Division of Nephrology, China Medical University Hospital, Taichung, Taiwan; Department of Internal Medicine, China Medical University College of Medicine, Taichung, Taiwan.
authors.forename: I-K
authors.initials: IK
authors.lastname: Wang
authors.forename: H-J
authors.initials: HJ
authors.lastname: Chen
authors.forename: Y-K
authors.initials: YK
authors.lastname: Cheng
authors.forename: Y-Y
authors.initials: YY
authors.lastname: Wu
authors.forename: S-Y
authors.initials: SY
authors.lastname: Lin
authors.forename: C-Y
authors.initials: CY
authors.lastname: Chou
authors.forename: C-T
authors.initials: CT
authors.lastname: Chang
authors.forename: T-H
authors.initials: TH
authors.lastname: Yen
authors.forename: F-R
authors.initials: FR
authors.lastname: Chuang
authors.forename: F-C
authors.initials: FC
authors.lastname: Sung
authors.forename: C Y
authors.initials: CY
authors.lastname: Hsu
mesh_terms: D000368:Aged; D015331:Cohort Studies; D015897:Comorbidity; D003920:Diabetes Mellitus / Q000453:epidemiology* / Q000401:mortality; D005260:Female; D006408:Hematoma, Subdural / Q000453:epidemiology* / Q000401:mortality; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012306:Risk; D013624:Taiwan / Q000453:epidemiology
keywords: diabetes mellitus; retrospective cohort study; subdural hematoma