title: Lamina replacement with titanium plate fixation improves spinal stability after total lumbar laminectomy.
abstract: Biomechanical experiments and strain analyses were performed to investigate the effects of lamina replacement surgery for intraspinal lesions on postoperative spinal stability. Eight specimens of thoracic and lumbar vertebrae (T12-L4) were collected from adult cadavers. Stepwise lumbar total laminectomy, and laminoplasty with lamina reduction and replacement was undertaken in combination with titanium-plate fixation to simulate the surgical setting. The effects of thoracic and lumbar vertebral strain, displacement, and rigidity on spinal stability were measured following both single and multiple segment laminectomy. Significant differences in mechanical indices of stability were seen between stepwise laminectomy of lumbar vertebrae and normal specimens (p < 0.05), between lamina replacement in combination with titanium-plate fixation and laminectomy (p < 0.05), and between single- and multiple-segment laminectomy (p < 0.05). Differences between laminoplasty with lamina replacement in combination with titanium-plate fixation and normal specimens need to be examined for further study. Lumbar laminectomy followed by reduction and replacement, in combination with titanium-plate fixation, was shown to be beneficial in terms of preserving spinal stability and maintaining biomechanical function and spinal loading capability.
authors.affiliation: a Department of Orthopedics , Changzhou No.2 People's Hospital Affiliated to Nanjing Medical University , Changzhou 213000 , Jiangsu , China.
authors.forename: Luming
authors.initials: L
authors.lastname: Nong
authors.forename: Dong
authors.initials: D
authors.lastname: Zhou
authors.forename: Nanwei
authors.initials: N
authors.lastname: Xu
authors.forename: Rui
authors.initials: R
authors.lastname: Du
authors.forename: Xijia
authors.initials: X
authors.lastname: Jiang
mesh_terms: D000328:Adult; D001696:Biomechanical Phenomena / Q000187:drug effects; D001860:Bone Plates; D005260:Female; D006801:Humans; D007796:Laminectomy; D008159:Lumbar Vertebrae / Q000503:physiopathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D013314:Stress, Mechanical; D013904:Thoracic Vertebrae / Q000503:physiopathology / Q000601:surgery; D014025:Titanium / Q000494:pharmacology*; D016474:Weight-Bearing
chemical_list: D014025:Titanium
keywords: biomechanics; lamina replacement and titanium-plate fixation; spine; total laminectomy