title: Cardiac amyloidosis: a report of two cases.
abstract: Cardiac amyloidosis is a manifestation of multisystem disorder. The condition is rare, difficult to diagnose and invariably fatal. We report 2 cases of amyloidosis associated with plasma cell dyscrasia. A high index of clinical suspicion, echocardiographic clues (ventricular thickening, diastolic dysfunction, biatrial enlargement) and elevated cardiac biomarkers led to the diagnosis. Early institution of amyloid specific treatment should be the aim. Cardiac treatment is supportive and results are often disappointing.
authors.affiliation: Registrar, Department of Cardiology, Bombay Hospital Institute of Medical Sciences, New Marine Lines, Mumbai 400020, Maharashtra, India. Electronic address: cbmunjewar@yahoo.co.in.
authors.forename: Chandrashekhar
authors.initials: C
authors.lastname: Munjewar
authors.affiliation: Registrar, Department of Cardiology, Bombay Hospital Institute of Medical Sciences, New Marine Lines, Mumbai 400020, Maharashtra, India.
authors.forename: Rahul
authors.initials: R
authors.lastname: Agrawal
authors.affiliation: Professor and Head, Department of Cardiology, Bombay Hospital Institute of Medical Sciences, New Marine Lines, Mumbai 400020, Maharashtra, India.
authors.forename: Satyavan
authors.initials: S
authors.lastname: Sharma
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000175:diagnosis*; D015415:Biomarkers / Q000097:blood; D009202:Cardiomyopathies / Q000175:diagnosis*; D015897:Comorbidity; D003937:Diagnosis, Differential; D004562:Electrocardiography; D017809:Fatal Outcome; D006439:Hemodynamics; D006801:Humans; D008297:Male; D055815:Young Adult
chemical_list: D015415:Biomarkers
keywords: Cardiac amyloidosis; Plasma cell dyscrasia; Waldenstrom's macroglobulinemia