title: [Intensity-modulated radiation therapy and stereotactic body radiation therapy for head and neck tumors: evidence-based medicine].
abstract: Over the last decade, there have been many technical advances in radiation therapy, such as the spread of intensity-modulated conformal radiotherapy, and the rise of stereotactic body radiation therapy. By allowing better dose-to-target conformation and thus better organs at risk-sparing, these techniques seem very promising, particularly in the field of head and neck tumors. The present work aims at analyzing the level of evidence and recommendation supporting the use of high-technology radiotherapy in head and neck neoplasms, by reviewing the available literature.
authors.affiliation: Service d'oncologie-radiothérapie, centre hospitalier Lyon Sud, 165, chemin du Grand-Revoyet, 69310 Pierre-Bénite, France. Electronic address: ariane.lapierre@chu-lyon.fr.
authors.forename: A
authors.initials: A
authors.lastname: Lapierre
authors.affiliation: Département de radiothérapie, centre Jean-Perrin, 58, rue Montalembert, BP 392, 63011 Clermont-Ferrand cedex 1, France.
authors.forename: F
authors.initials: F
authors.lastname: Martin
authors.affiliation: Département de radiothérapie, centre Jean-Perrin, 58, rue Montalembert, BP 392, 63011 Clermont-Ferrand cedex 1, France.
authors.forename: M
authors.initials: M
authors.lastname: Lapeyre
mesh_terms: D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use; D000068818:Cetuximab; D059248:Chemoradiotherapy; D002986:Clinical Trials as Topic; D016371:Cranial Irradiation / Q000009:adverse effects / Q000379:methods*; D019317:Evidence-Based Medicine; D006258:Head and Neck Neoplasms / Q000532:radiotherapy* / Q000601:surgery* / Q000628:therapy; D006801:Humans; D015201:Meta-Analysis as Topic; D015337:Multicenter Studies as Topic; D009364:Neoplasm Recurrence, Local / Q000532:radiotherapy / Q000601:surgery; D009944:Organoplatinum Compounds / Q000627:therapeutic use; D058958:Organs at Risk; D011832:Radiation Injuries / Q000209:etiology / Q000517:prevention & control; D016634:Radiosurgery / Q000009:adverse effects; D011879:Radiotherapy Dosage; D050397:Radiotherapy, Intensity-Modulated / Q000009:adverse effects / Q000379:methods; D016896:Treatment Outcome
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D009944:Organoplatinum Compounds; D000068818:Cetuximab
keywords: Head and neck neoplasms; Intensity-modulated; Radiochirurgie; Radiosurgery; Radiotherapy; Radiothérapie; Radiothérapie conformationnelle avec modulation d’intensité; Tumeurs de la tête et du cou