title: Novel replication-competent circular DNA molecules from healthy cattle serum and milk and multiple sclerosis-affected human brain tissue.
abstract: Epidemiological data point to the involvement of a cow milk factor in the etiology of multiple sclerosis (MS). Eleven circular DNA molecules closely related to transmissible spongiform encephalopathy (TSE)-associated isolate Sphinx 1.76 were isolated from healthy cattle serum, cow milk, and serum and brain tissue from MS patients.
authors.affiliation: Division for the Characterization of Tumorviruses, Deutsches Krebsforschungszentrum, Heidelberg, Germany.
authors.forename: Corinna
authors.initials: C
authors.lastname: Whitley
authors.affiliation: Division for the Characterization of Tumorviruses, Deutsches Krebsforschungszentrum, Heidelberg, Germany.
authors.forename: Karin
authors.initials: K
authors.lastname: Gunst
authors.affiliation: Institute for Virology, Faculty of Veterinary Medicine, University of Leipzig, Leipzig, Germany.
authors.forename: Hermann
authors.initials: H
authors.lastname: Müller
authors.affiliation: Division for the Characterization of Tumorviruses, Deutsches Krebsforschungszentrum, Heidelberg, Germany.
authors.forename: Mathis
authors.initials: M
authors.lastname: Funk
authors.affiliation: Division for the Characterization of Tumorviruses, Deutsches Krebsforschungszentrum, Heidelberg, Germany.
authors.forename: Harald
authors.initials: H
authors.lastname: Zur Hausen
authors.affiliation: Division for the Characterization of Tumorviruses, Deutsches Krebsforschungszentrum, Heidelberg, Germany e.devilliers@dkfz.de.
authors.forename: Ethel-Michele
authors.initials: EM
authors.lastname: de Villiers