title: Mortality of elderly patients after two-stage reimplantation for total joint infection: a case-control study.
abstract: The mortality of two-stage reimplantation for periprosthetic joint infection in patients over the age of 80 has not previously been studied. We retrospectively reviewed 134 elderly patients undergoing two-stage reimplantation at 90 days, 1 year and 5 years and compared them to a matched cohort who underwent single-stage aseptic total joint revision. There was no significant difference in preoperative comorbidities between groups. The mortality rates for the two-stage and aseptic groups were 39.9% and 34.1% respectively with an overall mortality rate of 36.7%. There was no significant difference in mortality at any time point (95% CI: 29.4, 43.1). Two-stage reimplantation does not significantly increase the mortality of patients over the age of 80 when compared to a matched cohort undergoing aseptic revision at our institution.
authors.affiliation: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors.forename: Jonathan E
authors.initials: JE
authors.lastname: Webb
authors.affiliation: Department of Biostatistics, Mayo Clinic, Rochester, Minnesota.
authors.forename: Cathy D
authors.initials: CD
authors.lastname: Schleck
authors.affiliation: Department of Biostatistics, Mayo Clinic, Rochester, Minnesota.
authors.forename: Dirk R
authors.initials: DR
authors.lastname: Larson
authors.affiliation: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors.forename: David G
authors.initials: DG
authors.lastname: Lewallen
authors.affiliation: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors.forename: Robert T
authors.initials: RT
authors.lastname: Trousdale
mesh_terms: D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D016459:Prosthesis-Related Infections / Q000382:microbiology / Q000401:mortality* / Q000601:surgery; D012086:Reoperation / Q000401:mortality; D012189:Retrospective Studies
keywords: elderly; mortality; periprosthetic infection; total joint; two-stage reimplantation