title: A method to increase the nominal range resolution of a stack of parallel-plate ionization chambers.
abstract: A detector prototype based on a stack of 61 parallel-plate ionisation chambers (PPIC) interleaved with absorber plates of polymethyl methacrylate (PMMA) was assembled for transmission imaging purposes in ion beam therapy. The thickness of the absorber sheets in the PPIC stack determines the nominal range resolution of the detector. In the current set-up, 3 mm PMMA slabs are used. The signal of the 61 active channels of the stack thereby provides a discrete approximation of the Bragg curve in the detector. In this work, a data processing method to increase the range resolution (MIRR) in a stack of ionization chambers is presented. In the MIRR the position of the maximum of the Bragg curve is deduced from the ratio of measured signals in adjacent PPIC channels. The method is developed based on Bragg curves obtained from Monte Carlo simulations and validated with experimental data of a wedge-shaped PMMA phantom acquired with the PPIC stack using carbon ion beams. The influence of the initial beam energy and of phantom inhomogeneities on the MIRR is quantitatively evaluated. Systematic errors as well as inaccuracies related to signal noise are discussed and quantified. It is shown that with the MIRR an increased range resolution of 0.7 mm PMMA equivalent or 0.8 mm water equivalent thickness is achieved for the considered experimental data.
authors.affiliation: Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany. Ludwig Maximilian University Munich, Am Coulombwall 1, 85748 Garching, Germany.
authors.forename: I
authors.initials: I
authors.lastname: Rinaldi
authors.forename: S
authors.initials: S
authors.lastname: Brons
authors.forename: O
authors.initials: O
authors.lastname: Jäkel
authors.forename: B
authors.initials: B
authors.lastname: Voss
authors.forename: K
authors.initials: K
authors.lastname: Parodi
mesh_terms: D065638:Absorption, Radiation; D000465:Algorithms; D019904:Polymethyl Methacrylate / Q000737:chemistry; D061766:Proton Therapy / Q000295:instrumentation* / Q000379:methods; D012680:Sensitivity and Specificity
chemical_list: D019904:Polymethyl Methacrylate