title: Effective method for multi-scale gradient porous scaffold design and fabrication.
abstract: Function-based modeling is a highly flexible porous scaffold design approach for use in tissue engineering. It was recently proposed as a valid tool for constructing cellular structures by providing a compact representation of complex structures. However, current approaches have some limitations with regard to combining multiple function-based substructures. In this short communication, we propose an effective method for combination operations of multiple substructures based on given substructures and boundaries. With this proposed method, a functional gradient porous scaffold (FGPS) with multi-scale substructures could be easily constructed and directly fabricated by using additive manufacturing techniques.
authors.affiliation: Tianjin Key Laboratory for Control Theory & Applications in Complicated Systems, Tianjin University of Technology, Binshuixi Road No. 391, Xiqing District, Tianjin 300384, China. Electronic address: y79nzw@163.com.
authors.forename: Nan
authors.initials: N
authors.lastname: Yang
authors.affiliation: Engineering Training Center of Tianjin University of Technology, Tianjin University of Technology, Binshuixi Road No. 391, Xiqing District, Tianjin 300384, China.
authors.forename: Kuntao
authors.initials: K
authors.lastname: Zhou
mesh_terms: D016062:Porosity; D054457:Tissue Scaffolds
keywords: Additive manufacturing; Function-based method; Functional gradient porous scaffold; Multi-scale structure