title: Galloylated flavonol rhamnosides from the leaves of Calliandra tergemina with antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA).
abstract: Galloylated flavonol rhamnosides identified as kaempferol-3-O-(2″,3″,4″-tri-O-galloyl)-α-l-rhamnopyranoside, quercetin-3-O-(3″,4″-di-O-galloyl)-α-l-rhamnopyranoside, and quercetin-3-O-(2″,3″,4″-tri-O-galloyl)-α-l-rhamnopyranoside, together with five known galloylated and non-galloylated flavonol rhamnosides, were isolated from leaves of Calliandra tergemina (L.) Benth. Their structures were established using spectroscopic methods and their antibacterial activities against methicillin-resistant Staphylococcus aureus (MRSA) were evaluated by a microdilution method.
authors.affiliation: School of Science, Monash University Malaysia, Jalan Lagoon Selatan, 46150 Bandar Sunway, Selangor, Malaysia.
authors.forename: Elaine Wan Ling
authors.initials: EW
authors.lastname: Chan
authors.affiliation: Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, John Arbuthnott Building, 161 Cathedral Street, Glasgow G4 0RE, United Kingdom.
authors.forename: Alexander I
authors.initials: AI
authors.lastname: Gray
authors.affiliation: Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, John Arbuthnott Building, 161 Cathedral Street, Glasgow G4 0RE, United Kingdom.
authors.forename: John O
authors.initials: JO
authors.lastname: Igoli
authors.affiliation: School of Science, Monash University Malaysia, Jalan Lagoon Selatan, 46150 Bandar Sunway, Selangor, Malaysia.
authors.forename: Sui Mae
authors.initials: SM
authors.lastname: Lee
authors.affiliation: School of Science, Monash University Malaysia, Jalan Lagoon Selatan, 46150 Bandar Sunway, Selangor, Malaysia. Electronic address: goh.joo.kheng@monash.edu.
authors.forename: Joo Kheng
authors.initials: JK
authors.lastname: Goh
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D007887:Fabaceae / Q000737:chemistry*; D005419:Flavonoids; D044948:Flavonols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D044949:Kaempferols; D008712:Methicillin / Q000494:pharmacology*; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects*; D018515:Plant Leaves / Q000737:chemistry; D011794:Quercetin / Q000031:analogs & derivatives / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D005419:Flavonoids; D044948:Flavonols; D006027:Glycosides; D044949:Kaempferols; C000594759:kaempferol-3-O-(2',3',4'-tri-O-galloyl)-alpha-L-rhamnopyranoside; C554714:quercetin-3-O-((6'''-O-caffeoyl)-alpha-L-rhamnose-(1-2)-beta-D-glucopyranosyl)-5-O-beta-D-glucopyranoside; C000594761:quercetin-3-O-(2',3',4'-tri-O-galloyl)-alpha-L-rhamnopyranoside; D011794:Quercetin; D008712:Methicillin
keywords: Antimicrobial; Calliandra tergemina; Flavonol rhamnosides; Leguminosae; Methicillin-resistant Staphylococcus aureus