title: Biocomposites of nanofibrillated cellulose, polypyrrole, and silver nanoparticles with electroconductive and antimicrobial properties.
abstract: In this work, flexible and free-standing composite films of nanofibrillated cellulose/polypyrrole (NFC/PPy) and NFC/PPy-silver nanoparticles (NFC/PPy-Ag) have been synthesized for the first time via in situ one-step chemical polymerization and applied in potential biomedical applications. Incorporation of NFC into PPy significantly improved its film formation ability resulting in composite materials with good mechanical and electrical properties. It is shown that the NFC/PPy-Ag composite films have strong inhibition effect against the growth of Gram-positive bacteria, e.g., Staphylococcus aureus. The electrical conductivity and strong antimicrobial activity makes it possible to use the silver composites in various applications aimed at biomedical treatments and diagnostics. Additionally, we report here the structural and morphological characterization of the composite materials with Fourier-transform infrared spectroscopy, atomic force microscopy, and scanning and transmission electron microscopy techniques.
authors.affiliation: Process Chemistry Centre, Laboratory of Analytical Chemistry, ‡Process Chemistry Centre, Laboratory of Wood and Paper Chemistry, ∥Center for Functional Materials, Laboratory of Physical Chemistry, and #Center for Functional Materials, Physics, Åbo Akademi University , FI-20500 Turku, Finland.
authors.forename: Patrycja
authors.initials: P
authors.lastname: Bober
authors.forename: Jun
authors.initials: J
authors.lastname: Liu
authors.forename: Kirsi S
authors.initials: KS
authors.lastname: Mikkonen
authors.forename: Petri
authors.initials: P
authors.lastname: Ihalainen
authors.forename: Markus
authors.initials: M
authors.lastname: Pesonen
authors.forename: Carme
authors.initials: C
authors.lastname: Plumed-Ferrer
authors.forename: Atte
authors.initials: A
authors.lastname: von Wright
authors.forename: Tom
authors.initials: T
authors.lastname: Lindfors
authors.forename: Chunlin
authors.initials: C
authors.lastname: Xu
authors.forename: Rose-Marie
authors.initials: RM
authors.lastname: Latonen
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology*; D002482:Cellulose / Q000737:chemistry* / Q000494:pharmacology; D004553:Electric Conductivity; D053768:Metal Nanoparticles / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission / Q000379:methods; D058105:Polymerization; D011108:Polymers / Q000737:chemistry* / Q000494:pharmacology; D011758:Pyrroles / Q000737:chemistry* / Q000494:pharmacology; D018030:Silver Compounds / Q000737:chemistry* / Q000494:pharmacology*; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D011108:Polymers; D011758:Pyrroles; D018030:Silver Compounds; C067635:polypyrrole; D002482:Cellulose