title: [Experiences with price competition of biosimilar drugs in Hungary].
abstract: OBJECTIVE
  The aim of our study is to analyse the biosimilar bids of the Hungarian National Health Insurance Fund Administration in case of colony-stimulating factor and erythropoietin products.
  
  
  METHODS
  Data derived from the nationwide pharmaceutical database of Hungarian National Health Insurance Fund Administration. We analysed how the number of patients treated by colony-stimulating factor and erythropoietin products changed before (01.07.2011.-30.06.2012.) and after (01.07.2012.-30.06.2013.) the first biosimilar bid performed in March 2012 in Hungary.
  
  
  RESULTS
  In the 12 months before biosimilar bid 4167 patients received erythropoietin treatment, while in the first 12 months after the bid 3647 patients, resulting in a 12.5 % decline. In the 12 months before biosimilar bid 13974 patients received colony-stimulating factor treatment, while in the first 12 months after the bid 13352 patients, resulting in a 4.5% decline.
  
  
  CONCLUSIONS
  The analyses of the Hungarian price competition bid of biosimilar products showed a minimal decline in the number of patients under treatment by both colony-stimulating factor and erythropoietin products while the health insurance reimbursement of these drugs significantly decreased.
authors.forename: Lajos
authors.initials: L
authors.lastname: Hornyák
authors.forename: Zsolt
authors.initials: Z
authors.lastname: Nagy
authors.forename: Zsuzsanna
authors.initials: Z
authors.lastname: Tálos
authors.forename: Dóra
authors.initials: D
authors.lastname: Endrei
authors.forename: István
authors.initials: I
authors.lastname: Ágoston
authors.forename: Tímea
authors.initials: T
authors.lastname: Csákvári
authors.forename: Imre
authors.initials: I
authors.lastname: Boncz
mesh_terms: D059451:Biosimilar Pharmaceuticals / Q000191:economics*; D003132:Commerce; D004921:Erythropoietin / Q000191:economics*; D000069585:Filgrastim; D016179:Granulocyte Colony-Stimulating Factor / Q000191:economics*; D006801:Humans; D006814:Hungary; D019458:Insurance Coverage / Q000706:statistics & numerical data / Q000639:trends*; D007349:Insurance, Health, Reimbursement; D009313:National Health Programs; D011994:Recombinant Proteins / Q000191:economics; D013810:Therapeutic Equivalency
chemical_list: D059451:Biosimilar Pharmaceuticals; D011994:Recombinant Proteins; D004921:Erythropoietin; D016179:Granulocyte Colony-Stimulating Factor; D000069585:Filgrastim