title: A comparison of functional outcome in patients sustaining major trauma: a multicentre, prospective, international study.
abstract: OBJECTIVE
  To compare 6 month and 12 month health status and functional outcomes between regional major trauma registries in Hong Kong and Victoria, Australia.
  
  
  BACKGROUND
  Multicentres from trauma registries in Hong Kong and the Victorian State Trauma Registry (VSTR).
  
  
  METHODS
  Multicentre, prospective cohort study. Major trauma patients and aged ≥18 years were included. The main outcome measures were Extended Glasgow Outcome Scale (GOSE) functional outcome and risk-adjusted Short-Form 12 (SF-12) health status at 6 and 12 months after injury.
  
  
  RESULTS
  261 cases from Hong Kong and 1955 cases from VSTR were included. Adjusting for age, sex, ISS, comorbid status, injury mechanism and GCS group, the odds of a better functional outcome for Hong Kong patients relative to Victorian patients at six months was 0.88 (95% CI: 0.66, 1.17), and at 12 months was 0.83 (95% CI: 0.60, 1.12). Adjusting for age, gender, ISS, GCS, injury mechanism and comorbid status, Hong Kong patients demonstrated comparable mean PCS-12 scores at 6-months (adjusted mean difference: 1.2, 95% CI: -1.2, 3.6) and 12-months (adjusted mean difference: -0.4, 95% CI: -3.2, 2.4) compared to Victorian patients. Keeping age, gender, ISS, GCS, injury mechanism and comorbid status, there was no difference in the MCS-12 scores of Hong Kong patients compared to Victorian patients at 6-months (adjusted mean difference: 0.4, 95% CI: -2.1, 2.8) or 12-months (adjusted mean difference: 1.8, 95% CI: -0.8, 4.5).
  
  
  CONCLUSIONS
  The unadjusted analyses showed better outcomes for Victorian cases compared to Hong Kong but after adjusting for key confounders, there was no difference in 6-month or 12-month functional outcomes between the jurisdictions.
authors.affiliation: Accident and Emergency Medicine Academic Unit, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Trauma & Emergency Centre, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China.
authors.forename: Timothy H
authors.initials: TH
authors.lastname: Rainer
authors.affiliation: Accident and Emergency Medicine Academic Unit, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Trauma & Emergency Centre, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China.
authors.forename: Hiu Hung
authors.initials: HH
authors.lastname: Yeung
authors.affiliation: Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia; College of Medicine, Swansea University, West Glamorgan, Wales, United Kingdom.
authors.forename: Belinda J
authors.initials: BJ
authors.lastname: Gabbe
authors.affiliation: Accident and Emergency Medicine Academic Unit, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
authors.forename: Kai Y
authors.initials: KY
authors.lastname: Yuen
authors.affiliation: Accident and Emergency Department, Queen Elizabeth Hospital, Yau Ma Tei, Kowloon, Hong Kong SAR, China.
authors.forename: Hiu F
authors.initials: HF
authors.lastname: Ho
authors.affiliation: Accident and Emergency Department, Tuen Mun Hospital, Tuen Mun, New Territories, Hong Kong SAR, China.
authors.forename: Chak W
authors.initials: CW
authors.lastname: Kam
authors.affiliation: Accident and Emergency Department, Queen Elizabeth Hospital, Yau Ma Tei, Kowloon, Hong Kong SAR, China.
authors.forename: Annice
authors.initials: A
authors.lastname: Chang
authors.affiliation: Division of Neurosurgery, Department of Surgery, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
authors.forename: Wai S
authors.initials: WS
authors.lastname: Poon
authors.affiliation: Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia; Emergency and Trauma Centre, Alfred Hospital, Melbourne, Victoria, Australia.
authors.forename: Peter A
authors.initials: PA
authors.lastname: Cameron
authors.affiliation: Accident and Emergency Medicine Academic Unit, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Trauma & Emergency Centre, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China.
authors.forename: Colin A
authors.initials: CA
authors.lastname: Graham
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001315:Australia / Q000453:epidemiology; D005260:Female; D023261:Glasgow Outcome Scale; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009104:Multiple Trauma / Q000453:epidemiology*; D011446:Prospective Studies; D020127:Recovery of Function; D012042:Registries; D012737:Sex Factors