title: Medical management of children after liver transplantation.
abstract: OBJECTIVE
  Successful outcomes in patient, graft survival, and quality of life depend on the prevention, early detection, and treatment of possible complications. The aim of the study was to highlight the common outcomes focusing on the unique features in children. Medical follow-up of children after liver transplantation includes monitoring of surgical complications: biliary and vascular, rejection, infections, posttransplant lymphoproliferative disease, other malignancies, recurrent disease, graft function, hypertension, diabetes, renal failure, among other conditions. The goal is to maintain normal graft function on minimal immunosuppression to avoid medication-induced side-effects.
  
  
  RESULTS
  Recent findings include the importance of meticulous follow-up of Epstein-Barr virus and Cytomegalic virus viral load, leading to early diagnosis and improved prognosis, increased prevalence of renal toxicity, cognitive dysfunction, autoimmune, atopic and eosinophilic disease, oral hygiene and chronic hepatitis, and fibrosis of allografts.
  
  
  CONCLUSIONS
  Caring for children after liver transplantation is extremely rewarding; however, careful attention must be paid to a variety of systems with understanding of the distinctiveness of pediatrics to assure optimal outcomes.
authors.affiliation: Phoenix Children's Hospital, University of Arizona, Mayo Clinic, Phoenix, Arizona, USA.
authors.forename: Tamir
authors.initials: T
authors.lastname: Miloh
mesh_terms: D064591:Allografts; D002648:Child; D020031:Epstein-Barr Virus Infections / Q000209:etiology; D006085:Graft Survival; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects; D011788:Quality of Life; D012008:Recurrence