title: [Diagnostic role of contrast-enhanced whole-heart coronary magnetic resonance angiography in the evaluation of coronary artery disease].
abstract: OBJECTIVE
  To prospectively evaluate the diagnostic effectiveness of contrast-enhanced whole-heart coronary magnetic resonance angiography (CE-CMRA) in patients with suspected coronary artery disease (CAD) with conventional coronary angiography as the reference standard.
  
  
  METHODS
  A total of 72 subjects with suspected CAD scheduled for conventional coronary angiography underwent 3.0-T contrast-enhanced whole-heart CE-MRA. The imaging quality, diagnostic performance and accuracy of CE-MRA for detecting significant stenoses ( ≥ 50%) in coronary arteries were compared with that of quantitative coronary angiography (QCA).
  
  
  RESULTS
  The whole-heart CE-MRA examinations were successfully completed in 65 patients. Among 809 segments with a reference luminal diameter ≥ 1.5 mm on CAG, 105 segments on CE-MRA were evaluated as nonassessable(13.0%) and 704 segments assessable.If 105 nonassessable segments on CE-MRA were considered to have significant stenoses, CE-MRA correctly identified CAD in 36/38 patients and correctly ruled out CAD in 21/27 patients. CE-MRA yielded 93.8%, 85.4%, 53.2% and 98.9% for diagnostic sensitivity, specificity, positive predicative value(PPV) and negative predicative value(NPV) on the basis of per-segment versus 94.7%, 77.8%, 85.7% and 91.3% respectively on the basis of per-patient.
  
  
  CONCLUSIONS
  CE-CMRA provides sufficiently high sensitivity and NPV, but moderate specificity and PPV for the diagnosis of CAD.It may be used as an optional imaging modality for CAD screening.
authors.affiliation: Department of Radiology, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou 450003, China.
authors.forename: Yongli
authors.initials: Y
authors.lastname: Li
authors.affiliation: Department of Radiology, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou 450003, China.
authors.forename: Baoli
authors.initials: B
authors.lastname: Chen
authors.affiliation: Department of Radiology, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou 450003, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Guo
authors.affiliation: Department of Radiology, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou 450003, China.
authors.forename: Jianmin
authors.initials: J
authors.lastname: Lian
authors.affiliation: Department of Radiology, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou 450003, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Lin
authors.affiliation: Department of Radiology, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou 450003, China.
authors.forename: Jiaying
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Radiology, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou 450003, China.
authors.forename: Dapeng
authors.initials: D
authors.lastname: Shi
authors.affiliation: Department of Radiology, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou 450003, China. Email: xjlhzq@163.com.
authors.forename: Junling
authors.initials: J
authors.lastname: Xu
mesh_terms: D003287:Contrast Media; D017023:Coronary Angiography / Q000379:methods*; D003324:Coronary Artery Disease / Q000175:diagnosis*; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods*; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media