title: [Pulsed-dose rate brachytherapy in cervical cancers: why, how?].
abstract: The end of the production of 192 iridium wires terminates low dose rate brachytherapy and requires to move towards pulsed-dose rate or high-dose rate brachytherapy. In the case of gynecological cancers, technical alternatives exist, and many teams have already taken the step of pulsed-dose rate for scientific reasons. Using a projector source is indeed a prerequisite for 3D brachytherapy, which gradually installs as a standard treatment in the treatment of cervical cancers. For other centers, this change implies beyond investments in equipment and training, organizational consequences to ensure quality.
authors.affiliation: Département d'oncologie-radiothérapie, institut de cancérologie Gustave-Roussy, 114, rue Édouard-Vaillant, 94805 Villejuif cedex, France. Electronic address: renaud.mazeron@gustaveroussy.fr.
authors.forename: R
authors.initials: R
authors.lastname: Mazeron
authors.affiliation: Département de physique médicale, institut de cancérologie Gustave-Roussy, 114, rue Édouard-Vaillant, 94805 Villejuif cedex, France.
authors.forename: I
authors.initials: I
authors.lastname: Dumas
authors.affiliation: Département d'oncologie-radiothérapie, institut de cancérologie Gustave-Roussy, 114, rue Édouard-Vaillant, 94805 Villejuif cedex, France.
authors.forename: V
authors.initials: V
authors.lastname: Martin
authors.affiliation: Département de physique médicale, institut de cancérologie Gustave-Roussy, 114, rue Édouard-Vaillant, 94805 Villejuif cedex, France.
authors.forename: F
authors.initials: F
authors.lastname: Martinetti
authors.affiliation: Département de physique médicale, institut de cancérologie Gustave-Roussy, 114, rue Édouard-Vaillant, 94805 Villejuif cedex, France.
authors.forename: W
authors.initials: W
authors.lastname: Benhabib-Boukhelif
authors.affiliation: Département d'oncologie-radiothérapie, institut de cancérologie Gustave-Roussy, 114, rue Édouard-Vaillant, 94805 Villejuif cedex, France.
authors.forename: M-C
authors.initials: MC
authors.lastname: Gensse
authors.affiliation: Département d'oncologie-radiothérapie, institut de cancérologie Gustave-Roussy, 114, rue Édouard-Vaillant, 94805 Villejuif cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Chargari
authors.affiliation: Département de physique médicale, institut de cancérologie Gustave-Roussy, 114, rue Édouard-Vaillant, 94805 Villejuif cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Guemnie-Tafo
authors.affiliation: Département d'oncologie-radiothérapie, institut de cancérologie Gustave-Roussy, 114, rue Édouard-Vaillant, 94805 Villejuif cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Haie-Méder
mesh_terms: D001918:Brachytherapy / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D003131:Combined Modality Therapy; D019583:Dose Fractionation, Radiation; D004867:Equipment Design; D005260:Female; D006801:Humans; D020360:Neoadjuvant Therapy / Q000379:methods; D058958:Organs at Risk; D011785:Quality Assurance, Health Care; D011786:Quality Control; D011832:Radiation Injuries / Q000517:prevention & control; D011835:Radiation Protection; D011868:Radioisotopes / Q000008:administration & dosage; D011879:Radiotherapy Dosage; D061089:Radiotherapy, Image-Guided; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy* / Q000601:surgery
chemical_list: D011868:Radioisotopes
keywords: Cancer du col de l’utérus; Cervix cancer; Curiethérapie guidée par l’image; Débit de dose pulsé; Image-guided adaptive brachytherapy; Pulsed-dose rate