title: The influence of fear of falling on gait variability: results from a large elderly population-based cross-sectional study.
abstract: OBJECTIVE
  To compare gait variability among older community-dwellers with and without fear of falling and history of falls, and 2) to examine the association between gait variability and fear of falling while taking into account the effect of potential confounders.
  
  
  METHODS
  Based on a cross-sectional design, 1,023 French community-dwellers (mean age ± SD, 70.5 ± 5.0 years; 50.7% women) were included in this study. The primary endpoints were fear of falling, stride-to-stride variability of stride time and walking speed measured using GAITRite® system. Age, gender, history of falls, number of drugs daily taken per day, body mass index, lower-limb proprioception, visual acuity, use of psychoactive drugs and cognitive impairment were used as covariables in the statistical analysis. P-values less than 0.05 were considered as statistically significant.
  
  
  RESULTS
  A total of 60.5% (n=619) participants were non-fallers without fear of falling, 19% (n=194) fallers without fear of falling, 9.9% (n=101) non-fallers with fear of falling, and 10.7% (n=109) fallers with fear of falling. Stride-to-stride variability of stride time was significantly higher in fallers with fear of falling compared to non-fallers without fear of falling. Full adjusted linear regression models showed that only lower walking speed value was associated to an increase in stride-to-stride variability of stride time and not fear of falling, falls or their combination. While using a walking speed ≥ 1.14 m/s (i.e., level of walking speed that did not influence stride-to-stride variability of stride time), age and combination of fear of falling with history of previous falls were significantly associated with an increased stride-to-stride variability of stride time.
  
  
  CONCLUSIONS
  The findings show that the combination of fear of falling with falls increased stride-to-stride variability of stride time. However, the effect of this combination depended on the level of walking speed, increase in stride-to-stride variability of stride time at lower walking speed being related to a biomechanical effect overriding fear of falling-related effects.
authors.forename: Farah
authors.initials: F
authors.lastname: Ayoubi
authors.forename: Cyrille P
authors.initials: CP
authors.lastname: Launay
authors.forename: Anastasiia
authors.initials: A
authors.lastname: Kabeshova
authors.forename: Bruno
authors.initials: B
authors.lastname: Fantino
authors.forename: Cédric
authors.initials: C
authors.lastname: Annweiler
authors.affiliation: Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital, 49933 Angers Cedex 9, France. olbeauchet@chu-angers.fr.
authors.forename: Olivier
authors.initials: O
authors.lastname: Beauchet
mesh_terms: D000058:Accidental Falls; D000368:Aged; D003430:Cross-Sectional Studies; D005239:Fear; D005260:Female; D005684:Gait; D020233:Gait Disorders, Neurologic / Q000523:psychology; D006801:Humans; D008297:Male