title: Trypanosoma cruzi screening in Texas blood donors, 2008-2012.
abstract: Chagas disease is an important emerging disease in Texas that results in cardiomyopathy in about 30% of those infected with the parasite Trypanosoma cruzi. Between the years 2008 and 2012, about 1/6500 blood donors were T. cruzi antibody-confirmed positive. We found older persons and minority populations, particularly Hispanic, at highest risk for screening positive for T. cruzi antibodies during routine blood donation. Zip code analysis determined that T. cruzi is associated with poverty. Chagas disease has a significant disease burden and is a cause of substantial economic losses in Texas.
authors.affiliation: Section of Pediatric Tropical Medicine,Department of Pediatrics,National School of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital,Houston,TX,USA.
authors.forename: M N
authors.initials: MN
authors.lastname: Garcia
authors.affiliation: Section of Pediatric Tropical Medicine,Department of Pediatrics,National School of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital,Houston,TX,USA.
authors.forename: L
authors.initials: L
authors.lastname: Woc-Colburn
authors.affiliation: Gulf Coast Regional Blood Center,Houston,TX,USA.
authors.forename: S N
authors.initials: SN
authors.lastname: Rossmann
authors.affiliation: American Red Cross,Gaithersburg,MD,USA.
authors.forename: R L
authors.initials: RL
authors.lastname: Townsend
authors.affiliation: American Red Cross,Gaithersburg,MD,USA.
authors.forename: S L
authors.initials: SL
authors.lastname: Stramer
authors.affiliation: Blood Systems Incorporated,Scottsdale,AZ,USA.
authors.forename: M
authors.initials: M
authors.lastname: Bravo
authors.affiliation: Blood Systems Incorporated,Scottsdale,AZ,USA.
authors.forename: H
authors.initials: H
authors.lastname: Kamel
authors.affiliation: South Texas Blood & Tissue Center,San Antonio,TX,USA.
authors.forename: R
authors.initials: R
authors.lastname: Beddard
authors.affiliation: Coffee Memorial Blood Center,Amarillo,TX,USA.
authors.forename: M
authors.initials: M
authors.lastname: Townsend
authors.affiliation: Coffee Memorial Blood Center,Amarillo,TX,USA.
authors.forename: R
authors.initials: R
authors.lastname: Oldham
authors.affiliation: Section of Pediatric Tropical Medicine,Department of Pediatrics,National School of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital,Houston,TX,USA.
authors.forename: M E
authors.initials: ME
authors.lastname: Bottazzi
authors.affiliation: Section of Pediatric Tropical Medicine,Department of Pediatrics,National School of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital,Houston,TX,USA.
authors.forename: P J
authors.initials: PJ
authors.lastname: Hotez
authors.affiliation: Section of Pediatric Tropical Medicine,Department of Pediatrics,National School of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital,Houston,TX,USA.
authors.forename: K O
authors.initials: KO
authors.lastname: Murray
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000913:Antibodies, Protozoan / Q000097:blood; D001782:Blood Donors / Q000706:statistics & numerical data*; D014355:Chagas Disease / Q000453:epidemiology* / Q000469:parasitology; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D012959:Socioeconomic Factors; D013781:Texas / Q000453:epidemiology; D014349:Trypanosoma cruzi / Q000302:isolation & purification*; D055815:Young Adult
chemical_list: D000913:Antibodies, Protozoan
keywords: Blood donors; Chagas disease; RIPA; Trypanosoma cruzi; repeat reactive; risk factors; seroprevalence