title: Microdissection approaches in tuberculosis research.
abstract: Mycobacterium tuberculosis, a globally significant pathogen, results in active or latent tuberculosis. The granuloma is the characteristic lesion that offers insight into host-pathogen interactions in these distinct states. Microdissection provides a way to isolate and consequently investigate specific tissue sections. We review various techniques available and in use.
authors.affiliation: Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Covington, LA, USA; Veterinary Pathology (T32) Training Program, Tulane National Primate Research Center, Covington, LA, USA.
authors.forename: Teresa A
authors.initials: TA
authors.lastname: Hudock
authors.forename: Andrew A
authors.initials: AA
authors.lastname: Lackner
authors.forename: Deepak
authors.initials: D
authors.lastname: Kaushal
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D006099:Granuloma / Q000382:microbiology; D054884:Host-Pathogen Interactions; D006801:Humans; D042282:Microdissection; D018613:Microscopy, Confocal; D009169:Mycobacterium tuberculosis / Q000502:physiology*; D011323:Primates; D014376:Tuberculosis / Q000382:microbiology* / Q000503:physiopathology
keywords: Mycobacterium tuberculosis; dissection; granuloma; mesodissection; non-human primate