title: [Case of young woman with Graves' disease and incomplete distal renal tubular acidosis with severe progress and cardiac arrest].
abstract: Diagnostic of renal tubular disorders can be often difficult. Incomplete form of distal Renal Tubular Acidosis (dRta) in course of Graves' disease was de novo recognized in a young woman hospitalized with a deep deficiency of potassium in blood serum complicated with cardiac arrest. Series of tests assessing the types and severity of water-electrolyte, acid-base and thyroid disorders were performed during a complex diagnosis. During the treatment of acute phase of the disease we intensified efforts to maintain basic life functions and to eliminate deep water-electrolyte disturbances. In the second phase of the treatment we determined an underlying cause of the disease, recognized dRTA, and introduced a specific long-term electrolyte and hormonal therapy. To confirm the diagnosis oral test with ammonium chloride (Wrong-Davies' test) was performed. After completion of the diagnostic and therapeutic process, the patient was included in the nephrological supervision on an outpatient basis. The basic drug for the therapy was sodium citrate. After a year of observation and continuing treatment we evaluated therapeutic results as good and permanent.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Klimm
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Kade
authors.forename: Sebastian
authors.initials: S
authors.lastname: Spaleniak
authors.forename: Ivanna
authors.initials: I
authors.lastname: Dubchak
authors.forename: Stanisław
authors.initials: S
authors.lastname: Niemczyk
mesh_terms: D000141:Acidosis, Renal Tubular / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D002951:Citrates / Q000627:therapeutic use; D003937:Diagnosis, Differential; D018450:Disease Progression; D005260:Female; D006111:Graves Disease / Q000150:complications*; D006323:Heart Arrest / Q000209:etiology*; D006801:Humans; D007008:Hypokalemia / Q000209:etiology*; D008875:Middle Aged; D000077559:Sodium Citrate
chemical_list: D002951:Citrates; D000077559:Sodium Citrate