title: [Prediction of psychoses].
abstract: BACKGROUND
  The worldwide established early detection and prevention centers for psychosis follow the modern program of predictive, preventive and personalized medicine.
  
  
  OBJECTIVE
  If primary prevention is to succeed, the individual risk of the disease has to be estimated correctly and the psychosis onset has to be accurately predicted. Accordingly, this article presents the current possibilities for prediction.
  
  
  METHODS
  An overview on the recent prediction analyses in clinical high risk for psychosis research is provided.
  
  
  RESULTS
  The previously identified high-risk criteria achieve a considerable predictive power, which can be further enhanced by their combined use as well as other strategies of risk enrichment and risk stratification.
  
  
  CONCLUSIONS
  Clinical prediction already allows risk-adapted prevention measures and is currently being enhanced even further by additional biological brain diagnostics.
authors.affiliation: Klinik und Poliklinik für Psychiatrie und Psychotherapie, Klinikum der Universität zu Köln, Kerpener Str. 62, 50924, Köln, Deutschland, joachim.klosterkoetter@uk-koeln.de.
authors.forename: J
authors.initials: J
authors.lastname: Klosterkötter
mesh_terms: D006801:Humans; D015994:Incidence; D009483:Neuropsychological Tests; D011379:Prognosis; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D018570:Risk Assessment / Q000379:methods