title: Refractory chronic migraine: a consensus statement on clinical definition from the European Headache Federation.
abstract: The debate on the clinical definition of refractory Chronic Migraine (rCM) is still far to be concluded. The importance to create a clinical framing of these rCM patients resides in the complete disability they show, in the high risk of serious adverse events from acute and preventative drugs and in the uncontrolled application of therapeutic techniques not yet validated.The European Headache Federation Expert Group on rCM presents hereby the updated definition criteria for this harmful subset of headache disorders. This attempt wants to be the first impulse towards the correct identification of these patients, the correct application of innovative therapeutic techniques and lastly aim to be acknowledged as clinical entity in the next definitive version of the International Classification of Headache Disorders 3 (ICHD-3 beta).
authors.affiliation: Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy. paolo.martelletti@uniroma1.it.
authors.forename: Paolo
authors.initials: P
authors.lastname: Martelletti
authors.forename: Zaza
authors.initials: Z
authors.lastname: Katsarava
authors.forename: Christian
authors.initials: C
authors.lastname: Lampl
authors.forename: Delphine
authors.initials: D
authors.lastname: Magis
authors.forename: Lars
authors.initials: L
authors.lastname: Bendtsen
authors.forename: Andrea
authors.initials: A
authors.lastname: Negro
authors.forename: Michael Bjørn
authors.initials: MB
authors.lastname: Russell
authors.forename: Dimos-Dimitrios D
authors.initials: DD
authors.lastname: Mitsikostas
authors.forename: Rigmor Højland
authors.initials: RH
authors.lastname: Jensen
mesh_terms: D002908:Chronic Disease; D032921:Consensus; D005060:Europe; D006801:Humans; D008881:Migraine Disorders / Q000145:classification*; D014837:Voluntary Health Agencies / Q000592:standards*