title: Cyanide induced self assembly and copper recognition in human blood serum by a new carbazole AIEE active material.
abstract: New carbazole based AIEE material is synthesized with fluoro group which shows ESIPT induced AIEE in H2O:THF (80:20, v/v). The material selectively recognizes Cu(2+) and CN(-) ions in contrasting modes with detection limits of 5 × 10(-6)Mol L(-1) and 12×10(-5)Mol L(-1) respectively and acts as a dual action chemosensor. The recognition of copper has also been observed in human serum, thus facilitating the detection of increased level of free Cu(2+) ions and its quantification in human serum.
authors.affiliation: Indian Institute of Technology, Mandi, Himachal Pradesh, 175001, India.
authors.forename: Shilpa
authors.initials: S
authors.lastname: Sharma
authors.affiliation: Indian Institute of Technology, Mandi, Himachal Pradesh, 175001, India.
authors.forename: Chullikkattil P
authors.initials: CP
authors.lastname: Pradeep
authors.affiliation: Indian Institute of Technology, Mandi, Himachal Pradesh, 175001, India. Electronic address: abhimanew@iitmandi.ac.in.
authors.forename: Abhimanew
authors.initials: A
authors.lastname: Dhir
mesh_terms: D002227:Carbazoles / Q000737:chemistry*; D003300:Copper / Q000097:blood*; D003486:Cyanides / Q000494:pharmacology*; D046529:Microscopy, Electron, Transmission; D066244:Proton Magnetic Resonance Spectroscopy; D013055:Spectrophotometry, Infrared
chemical_list: D002227:Carbazoles; D003486:Cyanides; D003300:Copper
keywords: Aggregation induced emission enhancement (AIEE); Copper sensing; Cyanide sensing; Excited state intramolecular proton transfer (ESIPT); Fluorescence