title: Advances in managing breast cancer: a clinical update.
abstract: Although substantial progress has been made in the screening and management of breast cancer, globally it remains the most common cause of cancer and cancer death in women. While breast cancer is potentially curable when detected at an early stage, it remains incurable in the metastatic setting. Thus, given its high prevalence, improved prevention and treatment of metastases remains a clinically meaningful unmet need. We review here the advances made in the last several years in the screening and treatment of breast cancer and explore how our increased insight into the underlying biology of breast cancer has influenced our efforts to individualize patient care.
authors.affiliation: Breast Cancer Medicine Service, Department of Medicine Memorial Sloan Kettering Cancer Center New York, NY10065, USA ; Department of Medicine Weill Cornell Medical College New York, NY 10065, USA.
authors.forename: Ayca
authors.initials: A
authors.lastname: Gucalp
authors.affiliation: Department of Radiation Oncology Memorial Sloan Kettering Cancer Center New York, NY 10065, USA.
authors.forename: Gaorav P
authors.initials: GP
authors.lastname: Gupta
authors.affiliation: Breast Service, Department of Surgery Memorial Sloan Kettering Cancer Center New York, NY 10065, USA.
authors.forename: Melissa L
authors.initials: ML
authors.lastname: Pilewskie
authors.affiliation: Breast Imaging Service, Department of Radiology Memorial Sloan Kettering Cancer Center New York, NY 10065, USA.
authors.forename: Elizabeth J
authors.initials: EJ
authors.lastname: Sutton
authors.affiliation: Breast Cancer Medicine Service, Department of Medicine Memorial Sloan Kettering Cancer Center New York, NY10065, USA ; Department of Medicine Weill Cornell Medical College New York, NY 10065, USA.
authors.forename: Larry
authors.initials: L
authors.lastname: Norton