title: [Au]/[Pd] Multicatalytic processes: direct one-pot access to benzo[c]chromenes and benzo[b]furans.
abstract: A new synthetic protocol that combines the advantages offered by eco-friendly solvent-free reactions and sequential transformations is reported. This strategy offers straightforward access to benzo[c]chromenes and benzo[b]furans from commercially available starting materials. This two-step, one-pot strategy consists of an Au-catalyzed hydrophenoxylation process followed by Pd-catalyzed C-H activation or Mizoroki-Heck reactions. The selectivity of the process towards C-H activation or Mizoroki-Heck reaction can be easily tuned.
authors.affiliation: EaStCHEM School of Chemistry, University of St Andrews, St Andrews, KY16 9ST (UK), Fax: (+44) 1334-463808; Current address: Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812 (Japan).
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Oonishi
authors.forename: Adrián
authors.initials: A
authors.lastname: Gómez-Suárez
authors.forename: Anthony R
authors.initials: AR
authors.lastname: Martin
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Makida
authors.forename: Alexandra M Z
authors.initials: AM
authors.lastname: Slawin
authors.forename: Steven P
authors.initials: SP
authors.lastname: Nolan
mesh_terms: D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry; D001578:Benzopyrans / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D006046:Gold / Q000737:chemistry*; D055772:Green Chemistry Technology; D010165:Palladium / Q000737:chemistry*
chemical_list: D001572:Benzofurans; D001578:Benzopyrans; D010165:Palladium; D006046:Gold
keywords: CH activation; Mizoroki-Heck reaction; gold; green chemistry; palladium; synthetic methods