title: Coronary artery aneurysm occurring very late after drug-eluting stent implantation.
abstract: An 82-year old woman presented with chest pain and was diagnosed as having acute myocardial infarction. Coronary angiography (CAG) showed 90% stenosis in the proximal left anterior descending artery (LAD). The patient underwent percutaneous coronary intervention using a sirolimus-eluting stent (SES). A repeat CAG performed 6 months after SES implantation revealed no problems. Eight years later, the patient presented with recurrent angina. CAG showed severe stenosis of the SES with a large aneurysm. We performed off-pump coronary artery bypass grafting without ligation or plication of the LAD, but with the application of fibrin glue to the coronary artery aneurysm. The postoperative course was uneventful. The mechanism responsible for the occurrence of coronary artery aneurysms occurring late after drug-eluting stent implantation remains unclear, and the treatment strategy remains controversial. Herein, we discuss a surgical treatment for this rare entity.
authors.affiliation: Department of Cardiovascular Surgery, Tsukuba Memorial Hospital, Tsukuba-City, Ibaraki, Japan.
authors.forename: Kenichi
authors.initials: K
authors.lastname: Okamura
authors.affiliation: Department of Cardiovascular Surgery, Tsukuba Memorial Hospital, Tsukuba-City, Ibaraki, Japan suematsu@tf7.so-net.ne.jp.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Suematsu
authors.affiliation: Department of Cardiovascular Surgery, Tsukuba Memorial Hospital, Tsukuba-City, Ibaraki, Japan.
authors.forename: Sei
authors.initials: S
authors.lastname: Morizumi
authors.affiliation: Department of Cardiovascular Surgery, Tsukuba Memorial Hospital, Tsukuba-City, Ibaraki, Japan.
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Kawata
mesh_terms: D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000209:etiology; D002317:Cardiovascular Agents / Q000008:administration & dosage*; D003323:Coronary Aneurysm / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D017023:Coronary Angiography / Q000379:methods; D047549:Coronary Artery Bypass, Off-Pump; D054855:Drug-Eluting Stents; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage; D006801:Humans; D009203:Myocardial Infarction / Q000175:diagnosis / Q000628:therapy*; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects* / Q000295:instrumentation*; D011474:Prosthesis Design; D020123:Sirolimus / Q000008:administration & dosage*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D002317:Cardiovascular Agents; D015718:Fibrin Tissue Adhesive; D020123:Sirolimus
keywords: Coronary artery aneurysm; Coronary artery bypass grafting; Drug-eluting stent; Sirolimus-eluting stent