title: Long term complications of polycystic ovary syndrome (PCOS).
abstract: Polycystic ovary syndrome (PCOS) is a frequent endocrine disease affecting 10 to 15% of women. Menstrual disorders, hyperandrogenism and ultrasonographic aspect of ovaries are typical of the disease and are established diagnostic criteria. But PCOS has also long term complications frequently forgotten and underestimated. During pregnancy, gestational diabetes and gestational hypertensive disorders can occur. At an older age, metabolic disease such as glucose intolerance, type 2 diabetes or dyslipidaemia are frequently described. Women with PCOS have increased classical cardiovascular risks and increased subclinical cardio-vascular disease without proven increase of cardiovascular morbidity and mortality. Finally, endometrial cancer seems to be more frequent in women with PCOS. Therefore, PCOS have numerous long-term health risks and a life-long follow-up is necessary for these women "at-risk" to detect and prevent complications as soon as possible.
authors.affiliation: Department of Endocrine Gynaecology and Reproductive Medicine, hôpital Jeanne-de-Flandre, CHRU, avenue Eugène-Avinée, 59037, Lille cedex, France; Université Lille 2, Lille, France. Electronic address: maeliss.peigne@chru-lille.fr.
authors.forename: Maëliss
authors.initials: M
authors.lastname: Peigné
authors.affiliation: Department of Endocrine Gynaecology and Reproductive Medicine, hôpital Jeanne-de-Flandre, CHRU, avenue Eugène-Avinée, 59037, Lille cedex, France; Université Lille 2, Lille, France. Electronic address: didier.dewailly@chru-lille.fr.
authors.forename: Didier
authors.initials: D
authors.lastname: Dewailly
mesh_terms: D005260:Female; D006801:Humans; D011085:Polycystic Ovary Syndrome / Q000150:complications* / Q000628:therapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy
keywords: Cancer; Cardio-vascular disease; Complications; Health; PCOS; Pathologie cardio-vasculaire; SOPK; Santé