title: Revisiting the bromination of C-H bonds with molecular bromine by using a photo-microflow system.
abstract: The photobromination of C-H bonds by using molecular bromine was reinvestigated under microfluidic conditions. The continuous-flow method suppressed the production of dibrominated compounds and effectively produced the desired monobrominated products with high selectivity. Rapid bromination of benzylic substrates containing a photoaffinity azide group was achieved without any decomposition.
authors.affiliation: Department of chemistry, Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043 (Japan), Fax: (+81) 6-6850-5391.
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Manabe
authors.forename: Yuriko
authors.initials: Y
authors.lastname: Kitawaki
authors.forename: Masahiro
authors.initials: M
authors.lastname: Nagasaki
authors.forename: Koichi
authors.initials: K
authors.lastname: Fukase
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsubara
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Hino
authors.forename: Takahide
authors.initials: T
authors.lastname: Fukuyama
authors.forename: Ilhyong
authors.initials: I
authors.lastname: Ryu
keywords: bromination; bromine; microreactors; photoreactions