title: Frequency of cardiorenal syndrome type-I in hospitalized children with acute heart failure in a tertiary-care hospital.
abstract: OBJECTIVE
  To determine the frequency of cardiorenal syndrome in hospitalized children with acute heart failure.
  
  
  METHODS
  Descriptive study.
  
  
  METHODS
  Paediatric Intensive Care Unit, The Aga Khan University Hospital, Karachi, from December 2010 to December 2011.
  
  
  METHODS
  Sixty eight (68) children with acute heart failure fulfilling the selection criteria were evaluated for worsening of renal function (WRF). Serum creatinine was done at baseline and repeated at 72 hours to see the worsening of renal function. Estimated serum creatinine clearance was calculated by Schwartz formula.
  
  
  RESULTS
  Mean age of patients was 43.6 ± 55.2 months. There were 43 (63%) males, 70% were under 57 months of age. Mean weight on admission was 14.7 ± 19.13 kg and mean height was 83 cm (± 31.08 SD). Mean serum creatinine on admission was 0.77 mg/dl (± 1.18 SD). Worsening renal function was noted in 55 (81%) of children, out of those, majority 36 (70.5%) were under 5 years of age.
  
  
  CONCLUSIONS
  Worsening renal function was found in 81% of children admitted with the diagnosis of acute heart failure. Majority (70.5%) were under 5 years of age indicating a closer observation of renal status in younger age group to reduce, morbidity and mortality.
authors.affiliation: Department of Paediatrics and Child Health, The Aga Khan University Hospital, Karachi.
authors.forename: Mehjabeen
authors.initials: M
authors.lastname: Zaidi
authors.affiliation: Department of Paediatrics and Child Health, The Aga Khan University Hospital, Karachi.
authors.forename: Arshalooz Jamila
authors.initials: AJ
authors.lastname: Rahman
authors.affiliation: Department of Paediatrics and Child Health, The Aga Khan University Hospital, Karachi.
authors.forename: Anwarul
authors.initials: A
authors.lastname: Haque
authors.affiliation: Department of Paediatrics and Child Health, The Aga Khan University Hospital, Karachi.
authors.forename: Saleem
authors.initials: S
authors.lastname: Sadqani
authors.affiliation: Department of Paediatrics and Child Health, The Aga Khan University Hospital, Karachi.
authors.forename: Prem Kumar
authors.initials: PK
authors.lastname: Maheshwari
mesh_terms: D000208:Acute Disease; D058186:Acute Kidney Injury / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D059347:Cardio-Renal Syndrome / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D003404:Creatinine / Q000097:blood*; D005260:Female; D006333:Heart Failure / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D007223:Infant; D015278:Intensive Care Units, Pediatric; D007677:Kidney Function Tests; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D011379:Prognosis; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D003404:Creatinine