title: Iron-catalyzed direct difunctionalization of alkenes with dioxygen and sulfinic acids: a highly efficient and green approach to β-ketosulfones.
abstract: A novel iron-catalyzed direct difunctionalization of alkenes with sulfinic acids and dioxygen for the synthesis of β-ketosulfones has been developed under mild conditions. The present protocol, which utilizes an inexpensive iron salt as the catalyst, readily available benzenesulfinic acids as the sulfonylating reagents, and dioxygen as the oxidant and oxygen source, provides a cost-effective and environmentally benign approach to access various β-ketosulfones.
authors.affiliation: The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China. huawang_qfnu@126.com.
authors.forename: Wei
authors.initials: W
authors.lastname: Wei
authors.forename: Jiangwei
authors.initials: J
authors.lastname: Wen
authors.forename: Daoshan
authors.initials: D
authors.lastname: Yang
authors.forename: Min
authors.initials: M
authors.lastname: Wu
authors.forename: Jinmao
authors.initials: J
authors.lastname: You
authors.forename: Hua
authors.initials: H
authors.lastname: Wang
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D055772:Green Chemistry Technology; D007501:Iron / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*; D013441:Sulfinic Acids / Q000737:chemistry*; D013450:Sulfones / Q000737:chemistry*
chemical_list: D000475:Alkenes; D013441:Sulfinic Acids; D013450:Sulfones; D007501:Iron; D010100:Oxygen