title: Synthesis of biaryl tertiary amines through Pd/norbornene joint catalysis in a remote C-H amination/Suzuki coupling reaction.
abstract: Here, we report on an efficient palladium/norbornene-catalyzed domino reaction of aryl halide, O-acyl hydroxylamine (R1R2N-OBz), and aromatic pinacol boronate (R-Bpin), selectively affording a series of biaryl tertiary amines in good to high yields with excellent functional group tolerance. This catalytic reaction provides a new opportunity for the convergent synthesis of biaryl amines from easily accessible starting materials.
authors.affiliation: Key Laboratory of Functional Small Organic Molecules, Ministry of Education, College of Chemistry & Chemical Engineering, Jiangxi Normal University , Nanchang, Jiangxi 330022, China.
authors.forename: Changqing
authors.initials: C
authors.lastname: Ye
authors.forename: Hui
authors.initials: H
authors.lastname: Zhu
authors.forename: Zhiyuan
authors.initials: Z
authors.lastname: Chen