title: The heterogeneity of changes in incidence and survival among lymphoid malignancies in a 30-year French population-based registry.
abstract: Our specialized population-based registry has allowed us to explore changes in incidence and survival by subtype over the last 30 years. Between 1980 and 2009, 4790 cases of lymphoid malignancies were registered using the International Classification of Diseases for Oncology. The incidence rate of lymphoid malignancies was 20.5 per 100,000 inhabitants per year, and ranged from 0.1 to 4 according to subtype. Five-year net survival was 65%, and ranged from 41% to 93% according to subtype. We observed an increase in 5-year net survival between the periods 1980-1989 and 2000-2009 (58% vs. 70%). This was observed in most but not all subtypes. Our long-standing population-based registry allowed us to measure differences in trends according to the subtype of lymphoid malignancy. Incidence rates steadily increased in quite frequent entities, and poor survival probability for most entities indicates that they should be the next objective in therapeutic research programs.
authors.affiliation: Registre des Hémopathies Malignes de Côte d'Or, EA 4184, Faculté de Médecine, Université de Bourgogne , Dijon , France.
authors.forename: Mylène
authors.initials: M
authors.lastname: Dandoit
authors.forename: Morgane
authors.initials: M
authors.lastname: Mounier
authors.forename: Julien
authors.initials: J
authors.lastname: Guy
authors.forename: Tony
authors.initials: T
authors.lastname: Petrella
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Girard
authors.forename: René-Olivier
authors.initials: RO
authors.lastname: Casasnovas
authors.forename: Laurent
authors.initials: L
authors.lastname: Martin
authors.forename: Franck
authors.initials: F
authors.lastname: Bonnetain
authors.forename: Marc
authors.initials: M
authors.lastname: Maynadié
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D005602:France / Q000453:epidemiology; D019337:Hematologic Neoplasms / Q000145:classification / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D007938:Leukemia / Q000145:classification / Q000453:epidemiology*; D008223:Lymphoma / Q000145:classification / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance / Q000379:methods; D012042:Registries / Q000706:statistics & numerical data*; D016019:Survival Analysis; D055815:Young Adult
keywords: Incidence; cancer registry; lymphoid malignancies; population-based; survival; trend