title: Treatment of aging vocal folds: surgical approaches.
abstract: OBJECTIVE
  Aging may affect the voice through either physiological or pathological changes. Globally society is aging and the working lifetime is extending. Increasing numbers of elderly will present with voice issues. This review examines current thinking regarding surgical treatment of the aging voice.
  
  
  RESULTS
  The mainstay of surgical treatment remains injection laryngoplasty and medialization thyroplasty. In-office injection laryngoplasty is increasingly common. Data suggest that patients with vocal fold atrophy do not achieve as much benefit from augmentation treatments as other causes of glottal incompetence. In addition the timing of injection laryngoplasty may influence the rate of subsequent medialization thyroplasty. Disease-specific treatments can provide some benefit to voice, such as deep brain stimulation in Parkinson's disease. Novel treatments including growth factor therapy are entering clinical practice and will provide new options for the clinician in future.
  
  
  CONCLUSIONS
  Voice disorders affect approximately 20% of the elderly population. Causes include neurologic, malignant, iatrogenic and benign vocal fold disorders. These should be ruled out before accepting dysphonia is age-related in nature. Treatment should be specific to recognized vocal disorders but may also address physiologic changes in the glottis. Injection laryngoplasty and thyroplasty remain effective options for treating glottal incompetence but novel therapies are showing promising results.
authors.affiliation: aDepartment of Otorhinolaryngology-Head and Neck Surgery, Kitasato University School of Medicine, Kitasato, Sagamihara, Kanagawa, Japan bUniversity of Auckland, Faculty of Medical and Health Sciences, Grafton, Auckland, New Zealand.
authors.forename: Yutomo
authors.initials: Y
authors.lastname: Seino
authors.forename: Jacqui E
authors.initials: JE
authors.lastname: Allen
mesh_terms: D000375:Aging / Q000473:pathology*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000627:therapeutic use; D058753:Laryngoplasty; D023822:Tissue Engineering; D014827:Vocal Cords / Q000473:pathology*; D014832:Voice Disorders / Q000473:pathology* / Q000601:surgery*; D014833:Voice Quality
chemical_list: D036341:Intercellular Signaling Peptides and Proteins