title: A novel graphene oxide based fluorescent nanosensing strategy with hybridization chain reaction signal amplification for highly sensitive biothiol detection.
abstract: A novel fluorescent nanosensor has been developed for detecting biothiols including cysteine and glutathione using graphene oxide based hairpin DNA-selective fluorescence quenching and thymine-Hg(II)-thymine coordination-controlled hybridization chain reaction, which provides a simple but the most sensitive platform for biothiol assays.
authors.affiliation: State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, P. R. China. xiachu@hnu.edu.cn.
authors.forename: Jia
authors.initials: J
authors.lastname: Ge
authors.forename: Zhi-Mei
authors.initials: ZM
authors.lastname: Huang
authors.forename: Qiang
authors.initials: Q
authors.lastname: Xi
authors.forename: Ru-Qin
authors.initials: RQ
authors.lastname: Yu
authors.forename: Jian-Hui
authors.initials: JH
authors.lastname: Jiang
authors.forename: Xia
authors.initials: X
authors.lastname: Chu
mesh_terms: D015374:Biosensing Techniques / Q000379:methods; D003545:Cysteine / Q000032:analysis*; D004247:DNA / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D005978:Glutathione / Q000032:analysis*; D006108:Graphite / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry*; D013941:Thymine / Q000737:chemistry
chemical_list: D005456:Fluorescent Dyes; D010087:Oxides; D006108:Graphite; D004247:DNA; D005978:Glutathione; D003545:Cysteine; D013941:Thymine