title: [Evaluation of peripheral neuropathy in the patients with type 2 diabetes mellitus by laboratory examination: relationship between albuminuria and ankle-brachial index].
abstract: The aim of this study was to investigate the influence of peripheral neuropathy on laboratory examinations and to evaluate the relationship between nerve conduction velocity (NCV), albuminuria, and ankle-brachial index (ABI) results in patients with type 2 diabetes mellitus (DM). One hundred twenty-six patients with type 2 DM who had undertaken the nerve conduction study for an initial screening test of diabetic complications were included in our study. We divided patients to 4 groups according to the stage of microalbuminuria and ABI results. Two factors negative (2FN) group (n = 75), urinary albumin creatinine ratio (A/C) < 30 mg/gCr and ABI > or = 1.0; A/C group (n = 25), A/C > or = 30 mg/gCr and ABI > or = 1.0; ABI group (n = 14), A/C < 30 mg/gCr and ABI < 1.0; two factors positive (2FP) group (n = 12), A/C > or = 30 mg/gCr and ABI < 1.0. Neuropathy, retinopathy, hypertension, macroangiopathy, and hyperlipidemia were seen in 57.9%, 38.1%, 59.5%, 22.2%, and 56.3%, respectively. Lower leg NCV in 2FP group was significantly lower than other groups. Our study indicated that impaired diabetic peripheral neuropathy may be detected by combining decreased ABI with increased A/C results.
authors.forename: Ayumi
authors.initials: A
authors.lastname: Hirose
authors.forename: Tsuneo
authors.initials: T
authors.lastname: Watanabe
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Nabetani
authors.forename: Yuzuru
authors.initials: Y
authors.lastname: Nohisa
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Furuta
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Kawachi
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Ito
authors.forename: Toshio
authors.initials: T
authors.lastname: Matsuoka
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Seishima
mesh_terms: D000419:Albuminuria / Q000150:complications*; D055109:Ankle Brachial Index; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D003925:Diabetic Angiopathies / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged