title: [Effects of size of pulmonary adenocarcinoma squamous carcinoma tumor on mediastinal lymphonode metastasis].
abstract: OBJECTIVE
  To explore the relationship between primary tumor size and mediastinal nodal metastases among different cell types in non-small cell lung cancer (NSCLC) and clarify the cutoff size for a higher likelihood of metastases.
  
  
  METHODS
  Retrospective evaluations were conducted for 1 346 NSCLC patients from January 2005 to January 2006. Primary focus was placed upon cases with primary tumor size < 8.0 cm.
  
  
  RESULTS
  It was shown that 2.0 cm was the critical cutoff size for increased mediastinal nodal metastases in adenocarcinoma (P < 0.01), but not in squamous cell carcinoma (P > 0.05).
  
  
  CONCLUSIONS
  Tumor size matters differently in pulmonary adenocarcinoma and squamous cell carcinoma.
authors.affiliation: Department of Respiratory Medicine, Affiliated Shanghai Pulmonary Hospital, Tongji University, Shanghai 200433, China.
authors.forename: Huailong
authors.initials: H
authors.lastname: Guo
authors.affiliation: Department of Respiratory Medicine, Affiliated Shanghai Pulmonary Hospital, Tongji University, Shanghai 200433, China.
authors.forename: Wen
authors.initials: W
authors.lastname: Gao
authors.affiliation: Department of Respiratory Medicine, Affiliated Shanghai Pulmonary Hospital, Tongji University, Shanghai 200433, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Zheng
authors.affiliation: Department of Respiratory Medicine, Affiliated Shanghai Pulmonary Hospital, Tongji University, Shanghai 200433, China. Email: changchenc@hotmail.com.
authors.forename: Chang
authors.initials: C
authors.lastname: Chen
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000077192:Adenocarcinoma of Lung; D002289:Carcinoma, Non-Small-Cell Lung; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D012189:Retrospective Studies