title: Phytochemical analysis, antimicrobial, antioxidant and urease inhibitory potential of Cyphostemma digitatum Lam.
abstract: In this paper we report the antimicrobial, antiradical and urease inhibitory potential along with photochemical investigation of the crude extracts of Cyphostemma digitatum Lam. Phytochemical screening of both the crude (hot/cold) alcoholic and aqueous extracts of C. digitatum showed the presence of alkaloids, flavonoids, saponins, coumarins, steroids, terpenoids and tannins. The crude methanolic extract (hot/cold) exhibited good antioxidant activity, while the aqueous extract was a weak antioxidant. The crude methanolic extract was found to be more active against Bacillus subtilis, while both the extracts showed moderate antifungal potential, the methanolic crude extract showed good urease inhibitory activity compared with the aqueous crude extract.
authors.affiliation: a Institute of Chemical Sciences, University of Peshawar , Peshawar - 25120 , KPK , Pakistan.
authors.forename: Rasool
authors.initials: R
authors.lastname: Khan
authors.forename: Abdullah Qasem
authors.initials: AQ
authors.lastname: Saif
authors.forename: Mohammad Mansour
authors.initials: MM
authors.lastname: Quradha
authors.forename: Jawad
authors.initials: J
authors.lastname: Ali
authors.forename: Abdur
authors.initials: A
authors.lastname: Rauf
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D000975:Antioxidants / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D064209:Phytochemicals / Q000494:pharmacology; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D014510:Urease / Q000037:antagonists & inhibitors*; D027844:Vitaceae / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D000975:Antioxidants; D064209:Phytochemicals; D010936:Plant Extracts; D014510:Urease
keywords: Cyphostemma digitatum; antimicrobial; antioxidant; phytochemical screening; urease inhibition activities