title: The effect of magnetic resonance imaging noise on cochlear function in dogs.
abstract: Noise produced by magnetic resonance imaging (MRI) scanners (which can peak at a sound pressure level of 131 dB) has been shown to cause noise-induced cochlear dysfunction in people. The aim of this study was to investigate whether noise produced during MRI had a deleterious effect on cochlear function in dogs, using distortion product otoacoustic emission (DPOAE) testing, which allows frequency specific, non-invasive assessment of cochlear function. DPOAE testing was performed before and after MRI in one or both ears under general anaesthesia at 14 frequency pairs (f2 frequency ranging from 0.84 kHz to 8.0 kHz). A control group comprised dogs undergoing anaesthesia of a similar duration for quiet procedures. Thirty-six dogs (66 ears) and 17 dogs (28 ears) were included in the MRI and control groups respectively. There was a reduction in DPOAE at all frequencies tested in the MRI group; a similar effect was not evident in the control group. This reduction in the MRI group was statistically significant in five of the 14 frequencies assessed (P < 0.05). These results demonstrate that exposure to MRI noise results in a significant reduction in frequency-specific cochlear function in dogs, although it is not known whether this is reversible or permanent. This suggests that all dogs undergoing MRI studies should be provided with ear protection as a routine precautionary measure.
authors.affiliation: School of Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Bearsden Road, Glasgow G61 1QH, UK.
authors.forename: R E
authors.initials: RE
authors.lastname: Venn
authors.affiliation: School of Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Bearsden Road, Glasgow G61 1QH, UK.
authors.forename: A R
authors.initials: AR
authors.lastname: McBrearty
authors.affiliation: Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Bearsden Road, Glasgow G61 1QH, UK.
authors.forename: D
authors.initials: D
authors.lastname: McKeegan
authors.affiliation: School of Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Bearsden Road, Glasgow G61 1QH, UK. Electronic address: Jacques.Penderis@Glasgow.ac.uk.
authors.forename: J
authors.initials: J
authors.lastname: Penderis
mesh_terms: D000818:Animals; D003051:Cochlea / Q000502:physiology*; D004285:Dogs / Q000502:physiology*; D005260:Female; D008279:Magnetic Resonance Imaging / Q000662:veterinary*; D008297:Male; D009622:Noise / Q000009:adverse effects*; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology*
keywords: DPOAE; Deafness; Distortion; Hearing; Noise-induced; Otoacoustic