title: ROP GTPase-mediated auxin signaling regulates pavement cell interdigitation in Arabidopsis thaliana.
abstract: In multicellular plant organs, cell shape formation depends on molecular switches to transduce developmental or environmental signals and to coordinate cell-to-cell communication. Plants have a specific subfamily of the Rho GTPase family, usually called Rho of Plants (ROP), which serve as a critical signal transducer involved in many cellular processes. In the last decade, important advances in the ROP-mediated regulation of plant cell morphogenesis have been made by using Arabidopsis thaliana leaf and cotyledon pavement cells. Especially, the auxin-ROP signaling networks have been demonstrated to control interdigitated growth of pavement cells to form jigsaw-puzzle shapes. Here, we review findings related to the discovery of this novel auxin-signaling mechanism at the cell surface. This signaling pathway is to a large extent independent of the well-known Transport Inhibitor Response (TIR)-Auxin Signaling F-Box (AFB) pathway, and instead requires Auxin Binding Protein 1 (ABP1) interaction with the plasma membrane-localized, transmembrane kinase (TMK) receptor-like kinase to regulate ROP proteins. Once activated, ROP influences cytoskeletal organization and inhibits endocytosis of the auxin transporter PIN1. The present review focuses on ROP signaling and its self-organizing feature allowing ROP proteins to serve as a bustling signal decoder and integrator for plant cell morphogenesis.
authors.affiliation: Center for Genomics and Biotechnology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
authors.forename: Deshu
authors.initials: D
authors.lastname: Lin
authors.forename: Huibo
authors.initials: H
authors.lastname: Ren
authors.forename: Ying
authors.initials: Y
authors.lastname: Fu
mesh_terms: D017360:Arabidopsis / Q000166:cytology* / Q000378:metabolism*; D020558:GTP Phosphohydrolases / Q000378:metabolism*; D007210:Indoleacetic Acids / Q000378:metabolism*; D059828:Plant Cells / Q000378:metabolism*; D010940:Plant Proteins / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D007210:Indoleacetic Acids; D010940:Plant Proteins; D020558:GTP Phosphohydrolases
keywords: Auxin; Rho of plants GTPase; leaf pavement cell