title: α-Heteroarylation of ketones via the umpolung reaction of N-alkoxyenamine.
abstract: A new method has been developed for the umpolung α-heteroarylation of ketones via an N-alkoxyenamine. The treatment of ketones with tris(heteroaryl)aluminum reagents in the presence of isoxazolidine gave the corresponding α-heteroarylated ketones in moderate to good yields.
authors.affiliation: Kobe Pharmaceutical University.
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Miyoshi
authors.forename: Norihiko
authors.initials: N
authors.lastname: Takeda
authors.forename: Masaki
authors.initials: M
authors.lastname: Fukami
authors.forename: Shohei
authors.initials: S
authors.lastname: Sato
authors.forename: Masafumi
authors.initials: M
authors.lastname: Ueda
authors.forename: Okiko
authors.initials: O
authors.lastname: Miyata
mesh_terms: D006571:Heterocyclic Compounds / Q000737:chemistry*; D006838:Hydrocarbons / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D021241:Spectrometry, Mass, Electrospray Ionization; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D006571:Heterocyclic Compounds; D006838:Hydrocarbons; D007659:Ketones