title: Stent-assisted coil embolization of a symptomatic middle cerebral artery aneurysm in an infant.
abstract: Pediatric intracranial aneurysms are rare and challenging to treat. Achieving efficacy and durability of aneurysmal occlusion while maintaining parent vessel patency requires innovative treatment strategies, especially in cases in which aneurysmal location or morphology pose substantial morbidity associated with microsurgical treatment. In the last 3 decades, endovascular treatments have had a remarkable evolution and are currently considered safe and effective therapeutic options for cerebral aneurysms. While endovascular techniques are well described in the English literature, the endovascular management of pediatric aneurysms continues to pose a challenge. In this report, the authors describe the case of a 9-month-old infant who presented with a 1-day history of acute-onset left-sided hemiparesis and left facial droop. Imaging revealed a large symptomatic saccular middle cerebral artery aneurysm. Treatment included successful stent-assisted aneurysm coiling. At follow-up, the patient continued to fare well and MR angiography confirmed complete occlusion of the aneurysm dome. This case features the youngest patient in the English literature to harbor an intracranial aneurysm successfully treated with stent-assisted coiling. Based on this experience, endovascular intervention with vascular reconstruction can be safe and effective for the treatment of infants and could further improve prognosis; however, further studies are necessary to confirm these findings.
authors.affiliation: Departments of 1 Neurosurgery and.
authors.forename: Luis E
authors.initials: LE
authors.lastname: Savastano
authors.forename: Neeraj
authors.initials: N
authors.lastname: Chaudhary
authors.forename: Joseph J
authors.initials: JJ
authors.lastname: Gemmete
authors.forename: Hugh J L
authors.initials: HJ
authors.lastname: Garton
authors.forename: Cormac O
authors.initials: CO
authors.lastname: Maher
authors.forename: Aditya S
authors.initials: AS
authors.lastname: Pandey
mesh_terms: D004621:Embolization, Therapeutic / Q000379:methods*; D006801:Humans; D007223:Infant; D002532:Intracranial Aneurysm / Q000175:diagnosis / Q000628:therapy*; D018810:Magnetic Resonance Angiography; D008297:Male; D011379:Prognosis; D015607:Stents; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014654:Vascular Patency
keywords: CE-MRA =contrast-enhanced MR angiography; CTA =CT angiography; DSA =digital subtraction angiography; ISAT =International Subarachnoid Aneurysm Trial; MCA =middle cerebral artery; MRA =MR angiography; SAC =stent-assisted coiling; embolization; pediatric intracranial aneurysm; stent-assisted coiling; vascular disorders