title: Fifteen years later, anthelmintic resistances have dramatically spread over goat farms in Guadeloupe.
abstract: Faecal egg count reduction tests (FECRTs) were performed on 21 goat farms in Guadeloupe (FWI). Anthelmintic resistance (AR) to netobimin (benzimidazole) was found in all 15 herds in which it was tested. AR to ivermectin (avermectin) and levamisole (imidazothiazole) were also very largely spread (14 out of 17 farms and 7 out of 9 farms, respectively). AR to the final moxidectin (milbemycin) released was already present in 2 out of 9 farms in which it was tested. Haemonchus was the dominant genus of gastrointestinal nematodes and was more frequently found to be resistant to netobimin, ivermectin and moxidectin than Trichostrongylus, the latter appeared to be more often resistant to levamisole. A first survey 15 years ago revealed only AR to benzimidazoles and one suspected case of AR to ivermectin.
authors.affiliation: INRA, UR143 Recherches Zootechniques, Domaine Duclos, F-97170 Petit bourg, Guadeloupe, France. Electronic address: maurice.mahieu@antilles.inra.fr.
authors.forename: Maurice
authors.initials: M
authors.lastname: Mahieu
authors.affiliation: INRA, UR143 Recherches Zootechniques, Domaine Duclos, F-97170 Petit bourg, Guadeloupe, France; Cabricoop, Rond Point Destrellan, F-97122 Baie mahault, Guadeloupe, France.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Ferré
authors.affiliation: Cabricoop, Rond Point Destrellan, F-97122 Baie mahault, Guadeloupe, France.
authors.forename: Marylène
authors.initials: M
authors.lastname: Madassamy
authors.affiliation: INRA, UR143 Recherches Zootechniques, Domaine Duclos, F-97170 Petit bourg, Guadeloupe, France.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Mandonnet
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use; D004351:Drug Resistance; D005243:Feces / Q000469:parasitology; D015511:Goat Diseases / Q000188:drug therapy / Q000453:epidemiology*; D006041:Goats; D019430:Guadeloupe / Q000453:epidemiology; D006188:Haemonchiasis / Q000188:drug therapy / Q000453:epidemiology / Q000662:veterinary*; D006189:Haemonchus / Q000187:drug effects*; D007559:Ivermectin / Q000031:analogs & derivatives / Q000627:therapeutic use; D007978:Levamisole / Q000627:therapeutic use; D018942:Macrolides / Q000627:therapeutic use; D010270:Parasite Egg Count / Q000662:veterinary; D011795:Surveys and Questionnaires; D014253:Trichostrongylosis / Q000188:drug therapy / Q000453:epidemiology / Q000662:veterinary*; D014254:Trichostrongylus / Q000187:drug effects*
chemical_list: D000871:Anthelmintics; D001562:Benzimidazoles; D018942:Macrolides; D007978:Levamisole; D007559:Ivermectin; C019264:avermectin; C031000:benzimidazole; C027837:moxidectin
keywords: Anthelmintic resistance; Goat; Haemonchus sp.; Trichostrongylus sp.