title: Serum brain-derived neurotrophic factor (BDNF) and its association with remission status in Chinese patients with schizophrenia.
abstract: The neurotrophin, brain-derived neurotrophic factor (BDNF), characterises a probable neurobiochemical explanation of maldevelopments in schizophrenia and is a candidate biomarker of the illness. A paucity of studies examining neurobiochemical predictors of remission in schizophrenia exists. In this study, we seek to examine if serum BDNF level is associated with remission status in a sample of Chinese patients with schizophrenia. This study did not find a significant relationship between serum BDNF and remission in patients with schizophrenia. Identification of a suitable biomarker for diagnosis, management, and prognostic outcome is crucial and warrants further study.
authors.affiliation: Research Division, Institute of Mental Health, Singapore.
authors.forename: Vidhya
authors.initials: V
authors.lastname: Renjan
authors.affiliation: Research Division, Institute of Mental Health, Singapore.
authors.forename: Milawaty
authors.initials: M
authors.lastname: Nurjono
authors.affiliation: Research Division, Institute of Mental Health, Singapore; Department of General Psychiatry 1, Institute of Mental Health, Singapore; Office of Clinical Sciences, Duke-NUS Graduate Medical School, Singapore. Electronic address: jimmy_lee@imh.com.sg.
authors.forename: Jimmy
authors.initials: J
authors.lastname: Lee
mesh_terms: D000328:Adult; D044466:Asian People; D015415:Biomarkers / Q000097:blood; D019208:Brain-Derived Neurotrophic Factor / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012559:Schizophrenia / Q000097:blood* / Q000175:diagnosis; D012720:Severity of Illness Index
chemical_list: D015415:Biomarkers; D019208:Brain-Derived Neurotrophic Factor
keywords: Biomarker; Neurotrophins; Psychosis; Response