title: Chronic calcific pancreatitis and pancreatic cancer.
abstract: An observational cross-sectional study of 50 cases of chronic calcific pancreatitis patients was conducted in Bangabandhu Sheikh Mujib Medical University (BSMMU) and some other tertiary level hospitals of Dhaka city from August 2008 to July 2010. Patients required laparotomy for different modalities of surgical treatment to manage chronic calcific pancreatitis were included in the study. Biopsy was taken from panceatic duct containing stone during laparotomy to determine the histopathological changes. Among 50 cases female predominance was observed. Male, female ratio was 2:3. Majority (62%) patients were in 20 to 40 years age group. Female presented earlier than male (20-30 years and 30-40 years respectively). All patients complained recurrent attack of epigastric pain. Other presentations were diabetes (74%), malnutrition and weight loss (56%), steatorrhoea (24%) and jaundice (12%). Adenocarcinoma was found in 3(6%) patients (2 male and 1 female) and rests were chronic pancreatitis. Several studies showed the association between chronic calcific pancreatitis and pancreatic cancer. Further large scale study is required to find out the national incidence level.
authors.affiliation: Dr Mallick Masum Billah, OSD, DGHS, In Attachment to Institute of Epidemiology, Disease Control and Research (IEDCR), Mohakhali, Dhaka, Bangladesh.
authors.forename: M M
authors.initials: MM
authors.lastname: Billah
authors.forename: M M
authors.initials: MM
authors.lastname: Chowdhury
authors.forename: B C
authors.initials: BC
authors.lastname: Das
authors.forename: N N
authors.initials: NN
authors.lastname: Shampa
authors.forename: Z R
authors.initials: ZR
authors.lastname: Khan
mesh_terms: D000328:Adult; D000368:Aged; D002114:Calcinosis / Q000150:complications*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000209:etiology*; D050500:Pancreatitis, Chronic / Q000150:complications*