title: Feasibility of three-dimensional virtual surgical planning in living liver donors.
abstract: OBJECTIVE
  The aim of the study was to determine the accuracy, reproducibility, and improvement in the clinical workflow of a semiautomatic computed tomography (CT) virtual surgical planning program in estimating graft volume using actual graft weight as a standard of reference in living liver donors.
  
  
  METHODS
  This retrospective study was approved by our Institutional Review Board and the requirement for informed consent was waived. A total of 105 liver donor candidates who underwent preoperative liver CT were reviewed. Volumes of the whole liver (V T), four hepatic segments, and predicted volumes of the hepatic graft (V pred) were obtained using a semiautomatic analysis program by radiologists and a conventional manual volumetry program by surgeons. Intraobserver and interobserver agreements of V T and V pred were assessed using intraclass correlation coefficients (ICCs). V pred was also compared to the actual graft weight (W act) and analysis times were recorded. In addition, potential vascular complications were assessed using the surgical planning function of the software.
  
  
  RESULTS
  The mean processing time of hepatic volumetry, segmentation, and surgical planning using software was significantly shorter than that using manual volumetry (175.9 ± 46.6 vs. 916.6 ± 52.8 s, P < 0.001). V T and V pred obtained using the semiautomatic analysis program showed significant intra and interobserver agreements (ICC = 0.98-0.99), and V pred showed strong correlation with W act (r = 0.83-0.86, P < 0.0001). Furthermore, image review using the liver analysis program detected 80% (4/5) vascular complications.
  
  
  CONCLUSIONS
  Liver volumetry and estimation of graft volume using liver analysis software provided good accuracy and excellent reproducibility in a short time than manual volumetry method and was useful for identifying vascular complications.
authors.affiliation: Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 110-744, Korea, jhjhry@gmail.com.
authors.forename: Jeong Hee
authors.initials: JH
authors.lastname: Yoon
authors.forename: Jeong Min
authors.initials: JM
authors.lastname: Lee
authors.forename: Ju Hyun
authors.initials: JH
authors.lastname: Jun
authors.forename: Kyung-Suk
authors.initials: KS
authors.lastname: Suh
authors.forename: Philippe
authors.initials: P
authors.lastname: Coulon
authors.forename: Joon Koo
authors.initials: JK
authors.lastname: Han
authors.forename: Byung Ihn
authors.initials: BI
authors.lastname: Choi
mesh_terms: D005240:Feasibility Studies; D006498:Hepatectomy; D006801:Humans; D007091:Image Processing, Computer-Assisted; D016031:Liver Transplantation; D019520:Living Donors; D012189:Retrospective Studies; D025321:Surgery, Computer-Assisted