title: Cerebral tumors: specific features in children.
abstract: Brain tumors are the second leading cause of cancer in children. Primary tumors predominate and are of very varied histological types. Their prognosis and treatment depend on the histological type and grade. The diagnostic approach to these includes analysis of the site of the lesion and appearances on computed tomography and MR, and taking account of the age and clinical features of the child. CT is used to diagnose the tumor in an emergency situation. Conventional MR provides a morphological approach and allows a staging assessment to be carried out before surgery. Advanced MR techniques (diffusion-weighted and perfusion imaging, MR spectroscopy) provide further information for the differential diagnosis, presumptive diagnosis of type and grade and to guide biopsy towards the most malignant areas in the lesion.
authors.affiliation: Department of Imaging 2, Pediatric Radiology, Hautepierre Hospital, Strasbourg University Hospital, 1, avenue Molière, 67098 Strasbourg cedex, France; ICube laboratory, FMT, UMR 7357/Strasbourg University CNRS, 67098 Strasbourg, France. Electronic address: meriam.koob@chru-strasbourg.fr.
authors.forename: M
authors.initials: M
authors.lastname: Koob
authors.affiliation: Department of Diagnostic and Interventional Radiology, Timone Public Hospitals Health Service, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France; CRMBM, UMR CNRS 7339, Aix-Marseille University, 13001 Marseille, France.
authors.forename: N
authors.initials: N
authors.lastname: Girard
mesh_terms: D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology; D002423:Cause of Death; D002648:Child; D003430:Cross-Sectional Studies; D003952:Diagnostic Imaging / Q000379:methods*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D018450:Disease Progression; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D055420:Perfusion Imaging / Q000379:methods; D011379:Prognosis; D014057:Tomography, X-Ray Computed / Q000379:methods
keywords: Brain; Child; Computed tomography; MRI; Tumor