title: Presence of Renal Simple Cysts Is Associated With Increased Risk of Abdominal Aortic Aneurysms.
abstract: We compared the incidence of renal simple cysts in 271 patients with abdominal aortic aneurysm (AAA) and 1387 patients without AAA (controls) using computed tomography (CT) angiography and abdominal CT, as a health screening program. The AAA group had significantly higher prevalence of renal simple cysts (55% vs 19%,P= .001) and chronic obstructive pulmonary disease (COPD; 12% vs 1%,P= .011) than the controls. After propensity score matching (n = 164), the prevalence of renal simple cysts was still significantly higher in the AAA group. In multivariate analysis, independent predictors of AAA were age, male gender, smoking history, hypertension, high-sensitivity C-reactive protein, creatinine, COPD, and renal simple cysts. The structural weakness predisposing for renal simple cysts may be associated with the initiation of AAA formation. More studies are needed to determine whether the presence of renal simple cysts can be considered as a risk factor for AAA.
authors.affiliation: Division of Cardiology, Department of Medicine, Cardiac and Vascular Center, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, South Korea.
authors.forename: Bong Gun
authors.initials: BG
authors.lastname: Song
authors.affiliation: Division of Cardiology, Department of Medicine, Cardiac and Vascular Center, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Republic of Korea.
authors.forename: Yong Hwan
authors.initials: YH
authors.lastname: Park
mesh_terms: D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000209:etiology*; D005260:Female; D006801:Humans; D015994:Incidence; D052177:Kidney Diseases, Cystic / Q000150:complications* / Q000000981:diagnostic imaging / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000453:epidemiology; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors
keywords: abdominal aortic aneurysm; connective tissue disorder; renal simple cysts