title: Closure of patent ductus arteriosus in low-birth weight infants based on three management strategies.
abstract: There is controversy on the most advantageous management for infants with patent ductus arteriosus (PDA) and whether to favor actively closing the PDA or to conservatively observe. We aimed to describe the outcome of infants with PDA based on three management strategies used for its closure (conservative, indomethacin, ligation).
  
  
  METHODS
  Retrospective medical record review of data from LBW infants (< 2000 with PDA admitted to NICU-SJCH.
  
  
  RESULTS
  The prevalence of PDA was 16%. Based on management strategies: 31% did not require treatment. 19% resolved with conservative measures, 38% resolved with omethacin treatment, and 12% required ligation. There was no difference in birth weight, gestational, clinical criteria, morbidities and mortality in patients managed with the strategies evaluated.
  
  
  CONCLUSIONS
  Results are consistent with previous reports. Development of PDA management guidelines will help standardize the definition of PDA and management criteria instead of treating on a case-by-case basis.
authors.forename: Andrea V
authors.initials: AV
authors.lastname: Rivera Sepúlveda
authors.forename: Norma
authors.initials: N
authors.lastname: Claudio
authors.forename: Lourdes
authors.initials: L
authors.lastname: García-Fragoso
mesh_terms: D006348:Cardiac Surgical Procedures / Q000379:methods; D003430:Cross-Sectional Studies; D004374:Ductus Arteriosus, Patent / Q000601:surgery*; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D012189:Retrospective Studies