title: [Iatrogenic events: a significant cause of admission in intensive care units].
abstract: OBJECTIVE
  Identification and analysis of iatrogenic events leading to admission in intensive care units.
  
  
  METHODS
  Prospective observational monocentric study.
  
  
  METHODS
  Critically ill patients hospitalized in adult medical intensive care unit of a general hospital over a twelve-month period.
  
  
  METHODS
  We recorded for each patient the following characteristics: origin, demographic datas, cause of admission, medical background, severity, diagnosis, ICU length of stay and provided treatments. Two medical investigators identified the iatrogenic character of events and determined their potential preventability. Univariate statistical analysis was performed.
  
  
  RESULTS
  During the study period, 603 patients were admitted and 71 (12%) due to iatrogenic events. In comparison to patients hospitalized for other causes, these patients were older (66 years vs. 60, P 0.009) and often previously treated in a hospital (82% vs. 54%, P<0.0001). They had increased need for transfusions (39% vs. 26%, P 0.02) but less frequent indications for mechanical ventilation (67% vs. 77%, P 0.07). They had similar ICU mortality (20% vs. 19%). Among them, 27 iatrogenic events were considered as preventable.
  
  
  CONCLUSIONS
  Iatrogenic event is a significant cause of ICU admission, involved in 12% of all the hospitalizations in our unit. It has an impact on the patient's profile (significantly older) and their ICU stay (increased need for transfusion). More than a third of events could be preventable and potentially accessible to corrective actions.
authors.affiliation: Service de réanimation médicale, centre hospitalier de Mulhouse, 20, avenue du Docteur-René-Lænnec, 68100 Mulhouse, France. Electronic address: poidevina@ch-mulhouse.fr.
authors.forename: A
authors.initials: A
authors.lastname: Poidevin
authors.affiliation: Service de réanimation médicale, centre hospitalier de Mulhouse, 20, avenue du Docteur-René-Lænnec, 68100 Mulhouse, France.
authors.forename: M
authors.initials: M
authors.lastname: Egard
authors.affiliation: Service de réanimation médicale, centre hospitalier de Mulhouse, 20, avenue du Docteur-René-Lænnec, 68100 Mulhouse, France.
authors.forename: P
authors.initials: P
authors.lastname: Guiot
authors.affiliation: Service de réanimation médicale, centre hospitalier de Mulhouse, 20, avenue du Docteur-René-Lænnec, 68100 Mulhouse, France.
authors.forename: K
authors.initials: K
authors.lastname: Kuteifan
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D003422:Critical Care / Q000706:statistics & numerical data*; D016638:Critical Illness; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data*; D006769:Hospitals, General; D006801:Humans; D007049:Iatrogenic Disease / Q000453:epidemiology* / Q000517:prevention & control; D007362:Intensive Care Units / Q000706:statistics & numerical data*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012121:Respiration, Artificial / Q000009:adverse effects; D012959:Socioeconomic Factors; D065227:Transfusion Reaction; D055815:Young Adult
keywords: Admission; Adverse event; Hospitalisation; Hospitalization; ICU admission; Iatrogenic disease; Iatrogenic event; Iatrogénie; Réanimation; Événement indésirable grave