title: Development and evaluation of a system to assess antimicrobial drug use in farm animals: results of an Austrian study.
abstract: The objective of this study was to develop and evaluate a feasible system for the collection of antimicrobial consumption data in farm animals in Austria. An electronic registry of all antibacterial pharmaceuticals approved in Austria for use in farm animals was created, listing product name, marketing authorisation number, active ingredient, package unit, strength, target species (cattle, swine, poultry), route of administration and indication, and allocating the corresponding code of the World Health Organization (WHO) Anatomical Therapeutic Chemical classification system for veterinary medicines to each substance (ATCvet-code). Different units (absolute quantities, animal daily dose, assumed daily product dose) enabled computation of the amounts of antimicrobials as pure substance, the constituents of a veterinary medicinal product, or the number of administrations. Two data collection systems were evaluated: (1) data transfer from the management software of veterinary practices or the Austrian Poultry Health Service; and (2) on-site data collection by manual data input from prescription records into an electronic registry. A total of 14,267 data sets provided by 18 practices were documented during the period January 2008 to March 2010. The total weight of active substances reported amounted to more than 5.4 tonnes for all species studied. The systems proved suitable for routine data acquisition and were considered in a recent national regulation on the surveillance of sale and consumption of veterinary antimicrobial substances.
authors.affiliation: Postplatz 7, Tamsweg 5580, Austria.
authors.forename: C
authors.initials: C
authors.lastname: Ferner
authors.affiliation: Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine Vienna, Institute of Veterinary Public Health, Veterinärplatz 1, Vienna 1210, Austria.
authors.forename: W
authors.initials: W
authors.lastname: Obritzhauser
authors.affiliation: Department for Data, Statistics and Risk Assessment, Austrian Agency for Health and Food Safety, Beethovenstrasse 8, Vienna 1210, Austria.
authors.forename: K
authors.initials: K
authors.lastname: Fuchs
authors.affiliation: Department for Biomedical Sciences, University of Veterinary Medicine Vienna, Institute of Pharmacology and Toxicology, Veterinärplatz 1, Vienna 1210, Austria.
authors.forename: I
authors.initials: I
authors.lastname: Schmerold
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D001317:Austria; D002417:Cattle; D004363:Drug Utilization / Q000706:statistics & numerical data*; D005240:Feasibility Studies; D011200:Poultry; D012042:Registries; D013552:Swine
chemical_list: D000890:Anti-Infective Agents