title: Surgical results of lumbar interbody fusion using calcium phosphate cement.
abstract: Clinical and radiological outcomes of lumbar interbody fusion using artificial fusion cages filled with calcium phosphate cements (CPCs) were retrospectively reviewed. Between 2002 and 2011, 25 patients underwent lumbar interbody fusion at Tokushima University Hospital, and 22 patients were enrolled in this study. Of these, 5 patients received autologous local bone grafts and 17 received CPC. Japan Orthopedic Association (JOA) score was used for clinical outcome assessments. Lumbar radiography and computed tomography (CT) were performed at 12, 24 months and last follow-up period to assess bony fusion. The mean JOA score of all patients improved from 9.3 before surgery to 21.0 at 24 months after surgery. Fusion had occurred in 5 of 5 patients in the local bone graft group and in 16 of 17 patients in CPC group at 24 months postoperatively. No surgically related complication was occurred in both groups. CPC is a useful and safe graft material for lumbar interbody fusion.
authors.affiliation: Department of Neurosurgery, Tokushima University.
authors.forename: Motohiro
authors.initials: M
authors.lastname: Hirasawa
authors.forename: Hideo
authors.initials: H
authors.lastname: Mure
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Toi
authors.forename: Shinji
authors.initials: S
authors.lastname: Nagahiro
mesh_terms: D000368:Aged; D001843:Bone Cements; D016025:Bone Transplantation / Q000295:instrumentation* / Q000379:methods*; D002809:Chondroitin Sulfates; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006882:Hydroxyapatites; D007090:Image Interpretation, Computer-Assisted; D055959:Intervertebral Disc Degeneration / Q000000981:diagnostic imaging* / Q000601:surgery*; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016348:Osseointegration / Q000502:physiology; D065289:Pedicle Screws; D019919:Prosthesis Implantation / Q000295:instrumentation* / Q000379:methods*; D012189:Retrospective Studies; D012600:Scoliosis / Q000000981:diagnostic imaging* / Q000601:surgery*; D013123:Spinal Fusion / Q000295:instrumentation* / Q000379:methods*; D013168:Spondylolisthesis / Q000000981:diagnostic imaging / Q000601:surgery*; D013386:Succinates; D014057:Tomography, X-Ray Computed
chemical_list: C481019:Biopex; D001843:Bone Cements; D006882:Hydroxyapatites; D013386:Succinates; D002809:Chondroitin Sulfates