title: Vasopressor weaning in patients with septic shock.
abstract: The purpose of this article is to propose optimal weaning of vasopressors in patients with septic shock. Topics discussed include pathophysiology of sepsis and septic shock, treatment guidelines for sepsis, autoregulation of blood flow, vasopressors used in septic shock, weaning recommendations, monitor alarms in the intensive care unit, and new directions in sepsis research.
authors.affiliation: Division of Critical Care, Department of Medicine, Houston Methodist Hospital, 6550 Fannin Street, Suite SM1001, Houston, TX 77030, USA; Department of Family Health, School of Nursing, University of Texas Health Science Center at Houston, Room# 796, 6901 Bertner Avenue, Houston, TX 77030, USA. Electronic address: Daniel.L.Arellano@uth.tmc.edu.
authors.forename: Daniel L
authors.initials: DL
authors.lastname: Arellano
authors.affiliation: Center for Nursing Research, School of Nursing, University of Texas Health Science Center at Houston, Room #594, 6901 Bertner Avenue, Houston, TX 77030, USA.
authors.forename: Sandra K
authors.initials: SK
authors.lastname: Hanneman
mesh_terms: D004305:Dose-Response Relationship, Drug; D006439:Hemodynamics; D006801:Humans; D007362:Intensive Care Units; D009638:Norepinephrine / Q000627:therapeutic use; D012772:Shock, Septic / Q000188:drug therapy*; D014662:Vasoconstrictor Agents / Q000627:therapeutic use*; D028761:Withholding Treatment
chemical_list: D014662:Vasoconstrictor Agents; D009638:Norepinephrine
keywords: Hypotension; Sepsis; Septic shock; Titration; Vasopressor; Wean