title: A brief report on outcomes of stereotactic ablative radiotherapy for a second primary lung cancer: evidence in support of routine CT surveillance.
abstract: New guidelines recommend the use of CT surveillance after a curative treatment for lung cancer as survivors have a 3-6% risk per person year of developing a second primary lung cancer. Our analysis of 107 patients with second primary lung cancer treated by stereotactic ablative radiotherapy showed a comparable 3 years overall survival (60%) and local control rate (89%) as for an initial lung cancer. Toxicity was uncommon, despite the fact that 73% of patients had undergone a prior (bi)lobectomy. Our findings indicate that CT surveillance is also appropriate in patients who may be unfit, or unwilling, to undergo surgery.
authors.affiliation: Department of Radiation Oncology, VU University Medical Center, Amsterdam, the Netherlands.
authors.forename: Gwendolyn H M J
authors.initials: GH
authors.lastname: Griffioen
authors.forename: Frank J
authors.initials: FJ
authors.lastname: Lagerwaard
authors.forename: Cornelis J A
authors.initials: CJ
authors.lastname: Haasbeek
authors.forename: Ben J
authors.initials: BJ
authors.lastname: Slotman
authors.forename: Suresh
authors.initials: S
authors.lastname: Senan
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D018572:Disease-Free Survival; D005260:Female; D006469:Hemoptysis / Q000209:etiology; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging* / Q000601:surgery*; D011013:Pneumonectomy; D011159:Population Surveillance; D017564:Radiation Pneumonitis / Q000209:etiology*; D016634:Radiosurgery / Q000009:adverse effects; D015996:Survival Rate; D014057:Tomography, X-Ray Computed