title: Childhood sexual abuse and depression in Latino men who have sex with men: Does resilience protect against nonadherence to antiretroviral therapy?
abstract: This study tested depression as a mediator between childhood sexual abuse and adherence to antiretroviral therapy, an effect moderated by resilience. In total, 149 HIV+ Latino men who have sex with men were recruited for this study. Using a regression-based bootstrap approach, depression mediated the relationship between childhood sexual abuse and antiretroviral therapy adherence, with worse adherence for participants at lowest percentiles of the resilience index. The prevalence of childhood sexual abuse and depression in HIV+ men who have sex with men is high and must be addressed to better prevent disease progression and reduce transmission, especially in expanding Latino populations.
authors.affiliation: University of California, San Francisco, USA john.sauceda@ucsf.edu.
authors.forename: John A
authors.initials: JA
authors.lastname: Sauceda
authors.affiliation: University of Texas at El Paso, USA.
authors.forename: John S
authors.initials: JS
authors.lastname: Wiebe
authors.affiliation: University of Washington, USA.
authors.forename: Jane M
authors.initials: JM
authors.lastname: Simoni
mesh_terms: D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D002648:Child; D002649:Child Abuse; D003866:Depressive Disorder / Q000453:epidemiology; D015658:HIV Infections / Q000188:drug therapy; D006630:Hispanic or Latino; D018451:Homosexuality, Male / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D055500:Resilience, Psychological; D012742:Sex Offenses; D000072339:Sexual and Gender Minorities
chemical_list: D044966:Anti-Retroviral Agents
keywords: HIV and AIDS; Latino/Hispanic; adherence; childhood sexual abuse; resilience