title: Adenosine receptor PET imaging in human brain.
abstract: Positron emission tomography (PET) is a nuclear medicine imaging technique that allows in vivo imaging of regional receptor-binding capacity. Advances in radiotracer chemistry have led to the development of novel imaging probes for adenosine receptors, especially adenosine A1 and A2A receptors. In this chapter, we discuss brain PET imaging for adenosine receptors and comparison of radioligands for PET imaging in health and diseases.
authors.affiliation: Department of Neurological Science, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan; Research Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan. Electronic address: mishina@nms.ac.jp.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Mishina
authors.affiliation: Research Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.
authors.forename: Kiich
authors.initials: K
authors.lastname: Ishiwata
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging* / Q000378:metabolism*; D006801:Humans; D049268:Positron-Emission Tomography; D018047:Receptors, Purinergic P1 / Q000378:metabolism*
chemical_list: D018047:Receptors, Purinergic P1
keywords: Adenosine A(1) receptor; Adenosine A(2A) receptor; Molecular imaging