title: MHC-II: a mutual support system for ILCs and T cells?
abstract: Innate and adaptive immune cells form an ongoing partnership during an immune response. In this issue of Immunity, Oliphant et al. (2014) show that MHC class II-peptide presentation by group 2 innate lymphoid cells is needed for reciprocal regulation of both cell types, resulting in effective antihelminth immunity.
authors.affiliation: Institute of Immunology and Infection Research, and Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, UK. Electronic address: rick.maizels@ed.ac.uk.
authors.forename: Rick M
authors.initials: RM
authors.lastname: Maizels
authors.affiliation: MRC Centre for Immune Regulation, Institute for Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, West Midlands B15 2TT, UK.
authors.forename: David R
authors.initials: DR
authors.lastname: Withers
mesh_terms: D000818:Animals; D002450:Cell Communication / Q000276:immunology*; D000949:Histocompatibility Antigens Class II / Q000276:immunology*; D009559:Nippostrongylus / Q000276:immunology*; D018418:Th2 Cells / Q000276:immunology*
chemical_list: D000949:Histocompatibility Antigens Class II