title: Croton insularis introduces the seco-casbane class with EBC-329 and the first casbane endoperoxide EBC-324.
abstract: Investigation of Croton insularis afforded the first in class seco-casbane diterpene, EBC-329. A highly oxidised casbane, EBC-324, was also isolated. The structural motif within EBC-324, which consists of an epoxidised hemi-acetal endoperoxide, is new to the casbane family.
authors.affiliation: QIMR Berghofer Medical Research Institute, PO Royal Brisbane Hospital, Brisbane, 4029, Queensland, Australia.
authors.forename: Lidiya A
authors.initials: LA
authors.lastname: Maslovskaya
authors.forename: Andrei I
authors.initials: AI
authors.lastname: Savchenko
authors.forename: Elizabeth H
authors.initials: EH
authors.lastname: Krenske
authors.forename: Victoria A
authors.initials: VA
authors.lastname: Gordon
authors.forename: Paul W
authors.initials: PW
authors.lastname: Reddell
authors.forename: Carly J
authors.initials: CJ
authors.lastname: Pierce
authors.forename: Peter G
authors.initials: PG
authors.lastname: Parsons
authors.forename: Craig M
authors.initials: CM
authors.lastname: Williams
mesh_terms: D029802:Croton / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D010545:Peroxides / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D004224:Diterpenes; D010545:Peroxides