title: Outcomes of nonsurgical periodontal therapy in severe generalized aggressive periodontitis.
abstract: OBJECTIVE
  Aggressive periodontitis, especially in its severe form, was traditionally considered to have an unfavourable prognosis. It required a complex treatment and its stabilization was often achieved by surgical therapy. The aim of this study was to investigate the results of nonsurgical periodontal treatment in severe generalized forms of aggressive periodontitis.
  
  
  METHODS
  Patients with advanced generalized aggressive periodontitis were included in the study. Probing depth (PD) of pockets ≥7 mm and clinical attachment level (CAL) of sites with attachment loss ≥5 mm were measured at baseline before nonsurgical periodontal treatment, at re-evaluation, and after treatment. The following other parameters were recorded: resolution of inflammation and bone fill. We compared the baseline values with re-evaluation and posttreatment values using the Friedman test. The Wilcoxon test with the Bonferroni correction was used for both re-evaluation and posttreatment values.
  
  
  RESULTS
  Seven patients with 266 periodontal sites were examined. A significant difference was found between values, reported as medians with interquartile ranges, for PD at baseline (7.94 [7.33-8.19] mm) and both re-evaluation (4.33 [3.63-5.08] mm) and posttreatment (3.54 [3.33-4.11] mm) values (P=0.002). A significant difference was also found between values for CAL at baseline (9.02 [7.5-9.2] mm) and both re-evaluation (6.55 [6.30-6.87] mm) and posttreatment (6.45 [5.70-6.61] mm) (P=0.002). Inflammation was resolved and angular bone defects were repaired in all cases.
  
  
  CONCLUSIONS
  These therapeutic results suggest that this form of periodontitis could have positive outcomes after nonsurgical periodontal treatment. The reparative potential of tissue affected by severe aggressive periodontitis should encourage clinicians to save apparently hopeless teeth in cases of this form of periodontitis.
authors.affiliation: Department of Periodontology, Faculty of Dental Medicine, Biostatistical, Clinical, and Epidemiological Research Laboratory, Faculty of Medicine and Pharmacy, Mohammed V Souissi University, Rabat, Morocco.
authors.forename: Amal
authors.identifier: 0000-0002-6723-5467
authors.initials: A
authors.lastname: Bouziane
authors.affiliation: Department of Periodontology, Faculty of Dental Medicine, Mohammed V Souissi University, Rabat, Morocco.
authors.forename: Latifa
authors.identifier: 0000-0002-8571-0444
authors.initials: L
authors.lastname: Benrachadi
authors.affiliation: Biostatistical, Clinical, and Epidemiological Research Laboratory, Faculty of Medicine and Pharmacy, Mohammed V Souissi University, Rabat, Morocco.
authors.forename: Redouane
authors.identifier: 0000-0002-6117-4341
authors.initials: R
authors.lastname: Abouqal
authors.affiliation: Department of Periodontology, Faculty of Dental Medicine, Mohammed V Souissi University, Rabat, Morocco.
authors.forename: Oumkeltoum
authors.identifier: 0000-0002-1224-9124
authors.initials: O
authors.lastname: Ennibi
keywords: Aggressive periodontitis; Periodontal debridement; Treatment outcome