title: Efficacy and tolerability of luliconazole cream 1% for dermatophytoses: a meta-analysis.
abstract: We evaluated the efficacy and safety of luliconazole cream 1% in the treatment of dermatophytoses. According to our meta-analysis, short-term treatment of luliconazole cream 1% can result in the complete clearance of dermatophytoses. It showed that 1% luliconazole was more effective than controlled drugs or vehicle (week 4: odds ratio = 1.46, 95% confidence interval = 1.12-1.91), and no more adverse events occurred in the 1% luliconazole group (week 4: odds ratio = 1.01, 95% confidence interval = 0.71-1.44). This effect strengthens the evidence for luliconazole cream 1% being more effective than vehicle, 1% terbinafine, 1% bifonazole, and 0.1% or 0.5% luliconazole.
authors.affiliation: Dermatology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Feng
authors.forename: Jinwei
authors.initials: J
authors.lastname: Xie
authors.forename: Kaiwen
authors.initials: K
authors.lastname: Zhuang
authors.forename: Yuping
authors.initials: Y
authors.lastname: Ran
mesh_terms: D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage* / Q000009:adverse effects; D016032:Randomized Controlled Trials as Topic; D063465:Skin Cream; D014005:Tinea / Q000188:drug therapy*
chemical_list: D007093:Imidazoles; C112528:luliconazole
keywords: antifungal; dermatophytoses; luliconazole; meta-analysis; randomized controlled trials