title: Impact of modulating phase duration on electrically evoked auditory brainstem responses obtained during cochlear implantation.
abstract: Objective To investigate the effect of increasing phase duration (pulse width, T-pulse) using a biphasic pulse composed of an initial anodic active phase followed by a balancing cathodic phase on the electrically evoked auditory brainstem responses (eABRs) recorded at the time of cochlear implantation. Design eABRs recorded during 188 surgeries for cochlear implantation from 1999 to 2006 in a single center were retrospectively reviewed by two independent observers. All patients were fitted with a NEURELEC cochlear implant (CI) device, initially DIGISONIC(®) then DIGISONIC SP(®) (2004-2006). Result Immediately following cochlear implantation, stimulation by the CI resulted in reliable wave III and V eABR waveforms (mean wave III latency 2.23 ± 0.38 ms SD and wave V latency 4.28 ± 0.42 ms SD). Latencies followed an apical to basal gradient (0.32 ms increase in mean eV latency and 0.12 ms for eIII latency). With increasing phase duration, wave III and wave V latencies significantly decreased in association with a shortening of the eIII-eV interwave gap, while amplitudes of both waves increased. Conclusion The impact of increasing phase duration on latency and amplitude of brainstem responses in a large set of patients implanted with NEURELEC CIs was reported.
authors.forename: N-X
authors.initials: NX
authors.lastname: Bonne
authors.forename: D
authors.initials: D
authors.lastname: Douchement
authors.forename: G
authors.initials: G
authors.lastname: Hosana
authors.forename: J
authors.initials: J
authors.lastname: Desruelles
authors.forename: P
authors.initials: P
authors.lastname: Fayoux
authors.forename: I
authors.initials: I
authors.lastname: Ruzza
authors.forename: C
authors.initials: C
authors.lastname: Vincent
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D001309:Auditory Threshold / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D019929:Cochlear Implantation / Q000295:instrumentation; D003054:Cochlear Implants; D003638:Deafness / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D004558:Electric Stimulation / Q000379:methods*; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D006801:Humans; D007223:Infant; D008875:Middle Aged; D011930:Reaction Time; D012189:Retrospective Studies; D013997:Time Factors; D055815:Young Adult
keywords: Cochlear implant; Deafness; Electrically evoked auditory brainstem repsonses