title: Acid-catalyzed acylation reaction via C-C bond cleavage: a facile and mechanistically defined approach to synthesize 3-acylindoles.
abstract: A facile acid-catalyzed acylation of indoles with 1,3-dione as an eco-friendly acylating agent was developed. This protocol combines C-C bond cleavage and heterocyclic C-H bond functionalization to form new C-C bonds. Based on the detailed mechanistic studies, a credible mechanistic pathway was proposed.
authors.affiliation: State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China. fuweili@licp.cas.cn.
authors.forename: Qi
authors.initials: Q
authors.lastname: Xing
authors.forename: Pan
authors.initials: P
authors.lastname: Li
authors.forename: Hui
authors.initials: H
authors.lastname: Lv
authors.forename: Rui
authors.initials: R
authors.lastname: Lang
authors.forename: Chungu
authors.initials: C
authors.lastname: Xia
authors.forename: Fuwei
authors.initials: F
authors.lastname: Li