title: Delay differential analysis of electroencephalographic data.
abstract: We propose a time-domain approach to detect frequencies, frequency couplings, and phases using nonlinear correlation functions. For frequency analysis, this approach is a multivariate extension of discrete Fourier transform, and for higher-order spectra, it is a linear and multivariate alternative to multidimensional fast Fourier transform of multidimensional correlations. This method can be applied to short and sparse time series and can be extended to cross-trial and cross-channel spectra (CTS) for electroencephalography data where multiple short data segments from multiple trials of the same experiment are available. There are two versions of CTS. The first one assumes some phase coherency across the trials, while the second one is independent of phase coherency. We demonstrate that the phase-dependent version is more consistent with event-related spectral perturbation analysis and traditional Morlet wavelet analysis. We show that CTS can be applied to short data windows and yields higher temporal resolution than traditional Morlet wavelet analysis. Furthermore, the CTS can be used to reconstruct the event-related potential using all linear components of the CTS.
authors.affiliation: Howard Hughes Medical Institute, Computational Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, U.S.A., and Institute for Neural Computation, University of California San Diego, La Jolla, CA 92093, U.S.A. claudia@salk.edu.
authors.forename: Claudia
authors.initials: C
authors.lastname: Lainscsek
authors.forename: Manuel E
authors.initials: ME
authors.lastname: Hernandez
authors.forename: Howard
authors.initials: H
authors.lastname: Poizner
authors.forename: Terrence J
authors.initials: TJ
authors.lastname: Sejnowski
mesh_terms: D000368:Aged; D058256:Brain Waves / Q000502:physiology*; D004569:Electroencephalography / Q000295:instrumentation; D005071:Evoked Potentials / Q000502:physiology; D025461:Feedback, Physiological; D005260:Female; D005583:Fourier Analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D010812:Physical Stimulation; D011601:Psychophysics; D011930:Reaction Time / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted; D013997:Time Factors