title: Dielectric barrier discharge ionization in characterization of organic compounds separated on thin-layer chromatography plates.
abstract: A new method for on-spot detection and characterization of organic compounds resolved on thin layer chromatography (TLC) plates has been proposed. This method combines TLC with dielectric barrier discharge ionization (DBDI), which produces stable low-temperature plasma. At first, the compounds were separated on TLC plates and then their mass spectra were directly obtained with no additional sample preparation. To obtain good quality spectra the center of a particular TLC spot was heated from the bottom to increase volatility of the compound. MS/MS analyses were also performed to additionally characterize all analytes. The detection limit of proposed method was estimated to be 100 ng/spot of compound.
authors.affiliation: Department of Supramolecular Chemistry, Faculty of Chemistry, Adam Mickiewicz University in Poznan, Poznań, Poland.
authors.forename: Michał
authors.initials: M
authors.lastname: Cegłowski
authors.affiliation: Department of Biochemistry and Neurobiology, Faculty of Materials Science and Ceramics, AGH-University of Science and Technology, Krakow, Poland.
authors.forename: Marek
authors.initials: M
authors.lastname: Smoluch
authors.affiliation: Faculty of Microsystem Electronics and Photonics, Wroclaw University of Technology, Wroclaw, Poland.
authors.forename: Michał
authors.initials: M
authors.lastname: Babij
authors.affiliation: Faculty of Microsystem Electronics and Photonics, Wroclaw University of Technology, Wroclaw, Poland.
authors.forename: Teodor
authors.initials: T
authors.lastname: Gotszalk
authors.affiliation: Department of Biochemistry and Neurobiology, Faculty of Materials Science and Ceramics, AGH-University of Science and Technology, Krakow, Poland; Center for Polymer and Carbon Materials, Polish Academy of Sciences, Zabrze, Poland.
authors.forename: Jerzy
authors.initials: J
authors.lastname: Silberring
authors.affiliation: Department of Supramolecular Chemistry, Faculty of Chemistry, Adam Mickiewicz University in Poznan, Poznań, Poland.
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Schroeder
mesh_terms: D002855:Chromatography, Thin Layer / Q000295:instrumentation / Q000379:methods*; D006358:Hot Temperature; D015394:Molecular Structure; D009930:Organic Chemicals / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification; D015203:Reproducibility of Results; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000295:instrumentation / Q000379:methods*; D053719:Tandem Mass Spectrometry / Q000295:instrumentation / Q000379:methods*
chemical_list: D009930:Organic Chemicals