title: Phragmalin limonoids from the stem barks of Chukrasia tabularis var. velutina.
abstract: Seven new phragmalin limonoids, chukvelutilides I-O (1-7), were isolated from the stem barks of Chukrasia tabularis var. velutina. Their structures were elucidated by extensive spectroscopic analysis. Among them, compound 1 showed moderate lethal activity against brine shrimp larvae, with an LC50 value of 84.1 µM.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
authors.forename: Jun-Lin
authors.initials: JL
authors.lastname: Yin
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
authors.forename: Xin
authors.initials: X
authors.lastname: Fang
authors.affiliation: Department of Biogeography and Ecology, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
authors.forename: En-De
authors.initials: ED
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
authors.forename: Chun-Mao
authors.initials: CM
authors.lastname: Yuan
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
authors.forename: Shi-Fei
authors.initials: SF
authors.lastname: Li
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
authors.forename: Hong-Ping
authors.initials: HP
authors.lastname: He
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
authors.forename: Shun-Lin
authors.initials: SL
authors.lastname: Li
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
authors.forename: Ying-Tong
authors.initials: YT
authors.lastname: Di
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
authors.forename: Xiao-Jiang
authors.initials: XJ
authors.lastname: Hao
mesh_terms: D000818:Animals; D060829:Arthropod Proteins / Q000187:drug effects; D033862:Iron-Binding Proteins / Q000187:drug effects; D007814:Larva / Q000187:drug effects; D036701:Limonins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D029582:Meliaceae / Q000737:chemistry; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D016601:RNA-Binding Proteins / Q000187:drug effects
chemical_list: D060829:Arthropod Proteins; D033862:Iron-Binding Proteins; D036701:Limonins; D016601:RNA-Binding Proteins; C490888:artemin protein, brine shrimp; C000593079:phragmalin