title: Making Common Sense of Vaccines: An Example of Discussing the Recombinant AttenuatedSalmonellaVaccine with the Public.
abstract: Researchers have iterated that the future of synthetic biology and biotechnology lies in novel consumer applications of crossing biology with engineering. However, if the new biology's future is to be sustainable, early and serious efforts must be made towards social sustainability. Therefore, the crux of new applications of synthetic biology and biotechnology is public understanding and acceptance. The RASVaccine is a novel recombinant design not found in nature that re-engineers a common bacteria (Salmonella) to produce a strong immune response in humans. Synthesis of the RASVaccine has the potential to improve public health as an inexpensive, non-injectable product. But how can scientists move forward to create a dialogue of creating a 'common sense' of this new technology in order to promote social sustainability? This paper delves into public issues raised around these novel technologies and uses the RASVaccine as an example of meeting the public with a common sense of its possibilities and limitations.
authors.affiliation: The Centre for the Study of the Science and the Humanities, University of Bergen, Allégaten 34, Post Box 7805, 5020 Bergen, Norway.
authors.forename: Dorothy J
authors.initials: DJ
authors.lastname: Dankel
authors.affiliation: The Biodesign Institute, Center for Infectious Diseases and Vaccinology, Arizona State University, 1001 S McAllister Avenue, Tempe, AZ 85287 USA.
authors.forename: Kenneth L
authors.initials: KL
authors.lastname: Roland
authors.affiliation: The Biodesign Institute, Center for Infectious Diseases and Vaccinology, Arizona State University, 1001 S McAllister Avenue, Tempe, AZ 85287 USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Fisher
authors.affiliation: The Biodesign Institute, Center for Infectious Diseases and Vaccinology, Arizona State University, 1001 S McAllister Avenue, Tempe, AZ 85287 USA.
authors.forename: Karen
authors.initials: K
authors.lastname: Brenneman
authors.affiliation: The Centre for the Study of the Science and the Humanities, University of Bergen, Allégaten 34, Post Box 7805, 5020 Bergen, Norway.
authors.forename: Ana
authors.initials: A
authors.lastname: Delgado
authors.affiliation: Nucleus for Microbiology and Immunity, Center for Genomics and Bioinformatics and The School of Life Sciences, Universidad Mayor, Chile and Arizona State University, Camino la Piramide 5750, Huechuraba, 8580745 Chile.
authors.forename: Javier
authors.initials: J
authors.lastname: Santander
authors.affiliation: Synthetic Biology R&D, Bioscience Division, Life Science Solutions Group (LSG), Thermo Fisher Scientific, 5791 Van Allen Way, Carlsbad, CA 92008 USA.
authors.forename: Chang-Ho
authors.initials: CH
authors.lastname: Baek
authors.affiliation: The Biodesign Institute, Center for Infectious Diseases and Vaccinology, Arizona State University, 1001 S McAllister Avenue, Tempe, AZ 85287 USA.
authors.forename: Josephine
authors.initials: J
authors.lastname: Clark-Curtiss
authors.affiliation: The Centre for the Study of the Science and the Humanities, University of Bergen, Allégaten 34, Post Box 7805, 5020 Bergen, Norway.
authors.forename: Roger
authors.initials: R
authors.lastname: Strand
authors.affiliation: The Biodesign Institute, Center for Infectious Diseases and Vaccinology, Arizona State University, 1001 S McAllister Avenue, Tempe, AZ 85287 USA.
authors.forename: Roy
authors.initials: R
authors.lastname: Curtiss
keywords: Biotechnology; Ethics; Legal issues; Social aspects; Societal values; Society; Trust; Vaccine; Values