title: Progesterone skin test in severe attacks of angioedema during menstrual cycle.
abstract: Progesterone hypersensitivity (PH) is a rare clinical condition that displays hypersensitivity to endogenous or exogenous progesterone. It is characterized by cyclic dermatologic manifestations at the end of the luteal phase that disappear some days after menses. We present a case of 24-year-old woman showing severe angioedema attacks occurring from the first day of her menstruation and continuing for 4-5 days and having positive progesterone intradermal test (IDT). To our knowledge, there is no case in the literature which is coupled with PH isolated angioedema attacks. In this case report we will discuss diagnostic value of progesterone IDT.
authors.affiliation: Department of Obstetrics and Gynecology, Ankara Etlik Zubeyde Hanim AND Women's Health Teaching and Research Hospital, Ankara, Turkey. neslihanyerebasmaz@hotmail.com.
authors.forename: Neslihan
authors.initials: N
authors.lastname: Yerebasmaz
authors.affiliation: Department of Allergy and Immunology, GATA Haydarpasa Teaching Hospital, Istanbul, Turkey. kotiloglu@hotmail.com.
authors.forename: Ali
authors.initials: A
authors.lastname: Kutlu
authors.affiliation: Department of Dermatovenereology, Kasimpasa Military Hospital, Istanbul, Turkey. drersinaydin@yahoo.com.
authors.forename: Ersin
authors.initials: E
authors.lastname: Aydin
authors.affiliation: Department of Dermatovenereology, GATA Haydarpasa Teaching Hospital, Istanbul, Turkey. drercankarabacak@yahoo.com.
authors.forename: Ercan
authors.initials: E
authors.lastname: Karabacak
authors.affiliation: Department of Allergy and Immunology, GATA Haydarpasa Teaching Hospital, Istanbul, Turkey. samiozturkiz@hotmail.com.
authors.forename: Sami
authors.initials: S
authors.lastname: Ozturk
authors.affiliation: Department of Obstetrics and Gynecology, GATA Haydarpasa Teaching Hospital, Istanbul, Turkey. drismetgun@gmail.com.
authors.forename: Ismet
authors.initials: I
authors.lastname: Gun
mesh_terms: D000328:Adult; D000799:Angioedema / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008183:Luteal Phase; D011374:Progesterone / Q000008:administration & dosage*; D011372:Progestins / Q000008:administration & dosage*; D012882:Skin Tests
chemical_list: D011372:Progestins; D011374:Progesterone