title: Postural disturbances resulting from unilateral and bilateral diaphragm contractions: a phrenic nerve stimulation study.
abstract: Thoracoabdominal breathing movements are a complex source of postural disturbance, but there are contradictory reports in the literature with inspiration described as having either a backward or a forward disturbing effect. To elucidate the mechanisms underlying this phenomenon, the present study studied the postural disturbance caused by isolated contractions of the diaphragm. Eight male and four female healthy subjects followed an original paradigm of phrenic nerve stimulation (bilateral and unilateral) and "diaphragmatic" voluntary sniff maneuvers in the seated and standing postures. Center of gravity (CG) acceleration was calculated from force plate recordings, and respiratory kinematics were assessed with thoracic and abdominal sensor belts. CG and respiratory signals revealed that, while seated, bilateral phrenic stimulation and sniff maneuvers consistently produced expansion of the abdomen associated with a forward peak of CG acceleration. In the standing posture, the direction of the CG peak was reversed and always directed backward. Unilateral phrenic stimulation induced an additional medial-lateral acceleration of the CG, directed toward the nonactive side while seated, but in the opposite direction while standing. These results suggest that isolated diaphragmatic contractions produce a constant disturbing pattern for a given posture, but with opposite effects between standing and seated postures. This could be related to the different biomechanical configuration of the body in each posture, corresponding to distinct kinematic patterns of the osteoarticular chain. In addition, the lateral component of the CG acceleration induced by unilateral diaphragm contractions could be clinically relevant in patients with hemidiaphragm paralysis.
authors.affiliation: Laboratory of Posture and Movement Physiology, University Champollion, Albi, France; alain.hamaoui@univ-jfc.fr.
authors.forename: Alain
authors.initials: A
authors.lastname: Hamaoui
authors.affiliation: Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1158 "Neurophysiologie Respiratoire Expérimentale et Clinique", Paris, France; INSERM, UMR_S 1158 "Neurophysiologie Respiratoire Expérimentale et Clinique", Paris, France; Neuroscience Research Australia and University of New South Wales, Sydney, Australia;
authors.forename: Anna L
authors.initials: AL
authors.lastname: Hudson
authors.affiliation: Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1158 "Neurophysiologie Respiratoire Expérimentale et Clinique", Paris, France; INSERM, UMR_S 1158 "Neurophysiologie Respiratoire Expérimentale et Clinique", Paris, France; Centre de Recherche clinique de l'Institut Universitaire de Cardiologie et Pneumologie de Québec (CRIUCPQ), Quebec, Canada; and.
authors.forename: Louis
authors.initials: L
authors.lastname: Laviolette
authors.affiliation: Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1158 "Neurophysiologie Respiratoire Expérimentale et Clinique", Paris, France; INSERM, UMR_S 1158 "Neurophysiologie Respiratoire Expérimentale et Clinique", Paris, France;
authors.forename: Marie-Cécile
authors.initials: MC
authors.lastname: Nierat
authors.affiliation: CIAMS Laboratory, UFR STAPS, University Paris-Sud, Orsay, France.
authors.forename: Manh-Cuong
authors.initials: MC
authors.lastname: Do
authors.affiliation: Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1158 "Neurophysiologie Respiratoire Expérimentale et Clinique", Paris, France; INSERM, UMR_S 1158 "Neurophysiologie Respiratoire Expérimentale et Clinique", Paris, France; AP-HP, Groupe Hospitalier Pitié-Salpêtrière Charles Foix, Service de Pneumologie et Réanimation Médicale (Département "R3S"), Paris, France;
authors.forename: Thomas
authors.initials: T
authors.lastname: Similowski
mesh_terms: D000054:Acceleration; D000328:Adult; D001696:Biomechanical Phenomena / Q000502:physiology; D003964:Diaphragm / Q000502:physiology*; D004558:Electric Stimulation / Q000379:methods; D005260:Female; D006112:Gravitation; D006801:Humans; D008297:Male; D009068:Movement / Q000502:physiology; D009119:Muscle Contraction / Q000502:physiology*; D010791:Phrenic Nerve / Q000502:physiology*; D011187:Posture / Q000502:physiology*; D012119:Respiration
keywords: diaphragm; posture; respiration