title: Epicardial Fat Tissue Predicts Increased Long-Term Major Adverse Cardiac Event in Patients With Moderate Cardiovascular Risk.
abstract: We investigated the relationship between epicardial fat volume (EFV) measured by multislice computed tomography (MDCT) and long-term major adverse cardiac events (MACEs). Consecutive patients (n = 564) were enrolled in this retrospective study. Patients were divided into tertiles according to EFV. Patients were followed up for an average of 18 months. Patients in each tertile were similar in terms of gender and risk factors. Patients with greater EFV in the third group were more likely to be overweight (P = .001) and older (P = .001). High-density lipoprotein cholesterol levels were relatively lower in the third tertile (45 ± 9, 45 ± 11, and 43 ± 9 mg/dL, respectively; P = .018). The third group had a significantly higher rate of myocardial infarction (0.6%, 1.1%, and 3.7%, respectively; P = .043). The incidence of MACEs during the follow-up period was highest in the third group 15.9% (4.1%, 7.7%, and 15.9%, respectively; P = .001). Epicardial fat volume measured by MDCT was associated with increased long-term cardiovascular risk.
authors.affiliation: Department of Cardiology, Mevlana University School of Medicine, Konya, Turkey.
authors.forename: Seref
authors.initials: S
authors.lastname: Ulucan
authors.affiliation: Department of Cardiology, Mevlana University School of Medicine, Konya, Turkey.
authors.forename: Zeynettin
authors.initials: Z
authors.lastname: Kaya
authors.affiliation: Department of Radiology, Mevlana University School of Medicine, Konya, Turkey.
authors.forename: Duran
authors.initials: D
authors.lastname: Efe
authors.affiliation: Department of Cardiology, Mevlana University School of Medicine, Konya, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Keser
authors.affiliation: Department of Cardiology, Mevlana University School of Medicine, Konya, Turkey.
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Katlandur
authors.affiliation: Department of Cardiovascular Surgery, Mevlana University School of Medicine, Konya, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Aygun
authors.affiliation: Department of Cardiology, Mevlana University School of Medicine, Konya, Turkey.
authors.forename: Mehmet Sıddık
authors.initials: MS
authors.lastname: Ulgen
authors.affiliation: Department of Cardiology, Selcuk University School of Medicine, Konya, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Avci
authors.affiliation: Department of Cardiology, Erciyes University School of Medicine, Kayseri, Turkey.
authors.forename: Bekir
authors.initials: B
authors.lastname: Calapkorur
authors.affiliation: Department of Cardiology, Erciyes University School of Medicine, Kayseri, Turkey drmgkaya@yahoo.com.
authors.forename: Mehmet G
authors.initials: MG
authors.lastname: Kaya
mesh_terms: D000273:Adipose Tissue / Q000000981:diagnostic imaging*; D000367:Age Factors; D015415:Biomarkers / Q000097:blood; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D008075:Lipoproteins, HDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D050177:Overweight; D010496:Pericardium / Q000000981:diagnostic imaging*; D012189:Retrospective Studies; D012307:Risk Factors; D014057:Tomography, X-Ray Computed
chemical_list: D015415:Biomarkers; D008075:Lipoproteins, HDL
keywords: epicardial fat tissue; major adverse cardiac events; multislice computed tomography