title: Electrochemical and in vitro bioactivity of polypyrrole/ceramic nanocomposite coatings on 316L SS bio-implants.
abstract: The present investigation describes the versatile fabrication and characterization of a novel composite coating that consists of polypyrrole (PPy) and Nb2O5 nanoparticles. Integration of the two materials is achieved by electrochemical deposition on 316L stainless steel (SS) from an aqueous solution of oxalic acid containing pyrrole and Nb2O5 nanoparticles. Fourier transform infrared spectral (FTIR) and X-ray diffraction (XRD) studies revealed that the existence of Nb2O5 nanoparticles in PPy matrix with hexagonal structure. Surface morphological analysis showed that the presence of Nb2O5 nanoparticles strongly influenced the surface nature of the nanocomposite coated 316L SS. Micro hardness results revealed the enhanced mechanical properties of PPy nanocomposite coated 316L SS due to the addition of Nb2O5 nanoparticles. The electrochemical studies were carried out using cyclic polarization and electrochemical impedance spectroscopy (EIS) measurements. In order to evaluate the biocompatibility, contact angle measurements and in vitro characterization were performed in simulated body fluid (SBF) and on MG63 osteoblast cells. The results showed that the nanocomposite coatings exhibit superior biocompatibility and enhanced corrosion protection performance over 316L SS than pure PPy coatings.
authors.affiliation: Center of Research Excellence in Corrosion, King Fahd University of Petroleum and Minerals, Dhahran 31261, Kingdom of Saudi Arabia.
authors.forename: A
authors.initials: A
authors.lastname: Madhan Kumar
authors.affiliation: Department of Metallurgy and Ceramics Science, Tokyo Institute of Technology, Tokyo, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Nagarajan
authors.affiliation: Graduate School of Biomedical Science and Engineering/College of Medicine, Hanyang University, Sungdong-gu, Seoul, South Korea.
authors.forename: Suresh
authors.initials: S
authors.lastname: Ramakrishna
authors.affiliation: Energy Materials Laboratory, Hanyang University, Seoul 133-791, South Korea.
authors.forename: P
authors.initials: P
authors.lastname: Sudhagar
authors.affiliation: Energy Materials Laboratory, Hanyang University, Seoul 133-791, South Korea.
authors.forename: Yong Soo
authors.initials: YS
authors.lastname: Kang
authors.affiliation: Graduate School of Biomedical Science and Engineering/College of Medicine, Hanyang University, Sungdong-gu, Seoul, South Korea.
authors.forename: Hyongbum
authors.initials: H
authors.lastname: Kim
authors.affiliation: Center of Research Excellence in Corrosion, King Fahd University of Petroleum and Minerals, Dhahran 31261, Kingdom of Saudi Arabia.
authors.forename: Zuhair M
authors.initials: ZM
authors.lastname: Gasem
authors.affiliation: Department of Chemistry, Anna University, Chennai, India. Electronic address: nrajendran@annauniv.edu.
authors.forename: N
authors.initials: N
authors.lastname: Rajendran
mesh_terms: D001672:Biocompatible Materials; D045744:Cell Line, Tumor; D002516:Ceramics; D004563:Electrochemistry / Q000379:methods*; D006801:Humans; D066298:In Vitro Techniques; D018625:Microscopy, Atomic Force; D008855:Microscopy, Electron, Scanning; D053761:Nanocomposites; D011108:Polymers / Q000737:chemistry / Q000494:pharmacology*; D019736:Prostheses and Implants; D011758:Pyrroles / Q000737:chemistry / Q000494:pharmacology*; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
chemical_list: D001672:Biocompatible Materials; D011108:Polymers; D011758:Pyrroles; C067635:polypyrrole
keywords: Electrochemical deposition; MG63 osteoblast cell; Nano Nb(2)O(5); Nanocomposites; Polypyrrole