title: Megalopapilla in children: a spectral domain optical coherence tomography analysis.
abstract: OBJECTIVE
  To compare various optic nerve head (ONH) parameters and peripapillary retinal nerve fibre layer (pRNFL) thickness between megalopapilla cases and normal control using spectral domain optical coherence tomography (SD-OCT) in children.
  
  
  METHODS
  Fifty eyes with megalopapilla and 80 normal control eyes of totally 130 children between the ages of 6 and 15 were examined using SD-OCT. Optic nerve head parameters including disc diameter, cup-to-disc ratio, disc area, cup area, rim area, cup volume and rim volume, and pRNFL thickness were analysed and compared between two groups.
  
  
  RESULTS
  Megalopapilla group presented larger optic disc diameter, disc and cup area, cup-to-disc and cup-to-disc area ratio, when compared with normal control group. However, there is no difference in rim area (p = 0.25) and rim volume (p = 0.48) between the two groups. Average pRNFL thickness was higher in the megalopapilla group (p < 0.001).
  
  
  CONCLUSIONS
  Rim area, rim volume and pRNFL, which reflect the number of retinal nerve fibres, were preserved in children with megalopapilla. Various ONH parameters obtained with SD-OCT may be useful in the differential diagnosis of megalopapilla in children.
authors.affiliation: Department of Ophthalmology, Chonnam National University Medical School and Hospital, Gwangju, Korea.
authors.forename: Hyo Seok
authors.initials: HS
authors.lastname: Lee
authors.affiliation: Department of Ophthalmology, Chonnam National University Medical School and Hospital, Gwangju, Korea.
authors.forename: Sang Woo
authors.initials: SW
authors.lastname: Park
authors.affiliation: Department of Ophthalmology, Chonnam National University Medical School and Hospital, Gwangju, Korea.
authors.forename: Hwan
authors.initials: H
authors.lastname: Heo
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D005124:Eye Abnormalities / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D009412:Nerve Fibers / Q000473:pathology*; D009898:Optic Disk / Q000002:abnormalities*; D012029:Refraction, Ocular / Q000502:physiology; D012165:Retinal Ganglion Cells / Q000473:pathology*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology
keywords: child; glaucoma; optic disc; optical coherence tomography