title: The effects of weight loss after bariatric surgery on health-related quality of life and depression.
abstract: BACKGROUND
  In severe obesity, impairments in health-related quality of life (HRQoL) and dysphoric mood are reported. This is a post-surgery analysis of the relationship between HRQoL and depressive symptoms, and weight change after four different types of bariatric procedures.
  
  
  METHODS
  A total of 105 consented patients completed the Short-Form-36 Health Survey (SF-36), the Impact of Weight on Quality of Life-Lite (IWQOL-Lite) and the Beck Depression Inventory (BDI) before and 25 months after surgery. Analysis of variance or Kruskal-Wallis test evaluated changes.
  
  
  RESULTS
  Patients with Roux-en Y gastric bypass (46 patients), decreased body mass indexes (BMIs; kg m(-)(2)) 47-31 kg m(-)(2) (P<0.0001); biliopancreatic diversion with duodenal switch (18 patients), decreased BMIs 57-30 kg m(-)(2) (P<0.0001); adjustable gastric banding (18 patients), decreased BMIs 45-38 kg m(-)(2) (P<0.0001); and sleeve gastrectomies (23 patients), decreased BMIs 58 42 kg m(-)(2) (P<0.0001). The excess percentage BMI loss was 69, 89, 36 and 53 kg m(-)(2), respectively (P<0.0001). Before surgery, the SF-36 differences were significant regarding bodily pain (P=0.008) and social functioning (P=0.01). After surgery, physical function (P=0.03), general health (P=0.05) and physical component (P=0.03) were different. IWQOL-Lite recorded no differences until after surgery: physical function (P=0.003), sexual life (P=0.04) and public distress (P=0.003). BDI scores were not different for the four groups at baseline. All improved with surgery, 10.6-4.4 (P=0.0001).
  
  
  CONCLUSIONS
  HRQoL and depressive symptoms significantly improvement after surgery. These improvements do not have a differential effect over the wide range of weight change.Nutrition & Diabetes (2014) 4, e132; doi:10.1038/nutd.2014.29; published online 1 September 2014.
authors.affiliation: Department of Surgery, Weill Cornell College of Medicine, New York, NY, USA.
authors.forename: G W
authors.initials: GW
authors.lastname: Strain
authors.affiliation: Obesity and Quality of Life Consulting, and Duke University School of Medicine, Durham, NC, USA.
authors.forename: R L
authors.initials: RL
authors.lastname: Kolotkin
authors.affiliation: Department of Surgery, Weill Cornell College of Medicine, New York, NY, USA.
authors.forename: G F
authors.initials: GF
authors.lastname: Dakin
authors.affiliation: Department of Surgery, Hospital du Sacre Coeur, Montreal, Quebec, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Gagner
authors.affiliation: Department of Surgery, Mt Sinai Medical Center, New York, NY, USA.
authors.forename: W B
authors.initials: WB
authors.lastname: Inabnet
authors.affiliation: Department of Surgery, Weill Cornell College of Medicine, New York, NY, USA.
authors.forename: P
authors.initials: P
authors.lastname: Christos
authors.affiliation: Department of Surgery, Weill Cornell College of Medicine, New York, NY, USA.
authors.forename: T
authors.initials: T
authors.lastname: Saif
authors.affiliation: University of North Dakota Neuropsychiatry Institute, Fargo, ND, USA.
authors.forename: R
authors.initials: R
authors.lastname: Crosby
authors.affiliation: Department of Surgery, Weill Cornell College of Medicine, New York, NY, USA.
authors.forename: A
authors.initials: A
authors.lastname: Pomp