title: Patient-reported outcomes in obsessive-compulsive disorder.
abstract: The purpose of the article was to provide an overview of patient-reported outcomes (PROs) and related measures that have been examined in the context of obsessive-compulsive disorder (OCD). The current review focused on patient-reported outcome measures (PROMs) that evaluated three broad outcome domains: functioning, health-related quality of life (HRQoL), and OCD-related symptoms. The present review ultimately included a total of 155 unique articles and 22 PROMs. An examination of the PROs revealed that OCD patients tend to suffer from significant functional disability, and report lower HRQoL than controls. OCD patients report greater symptom severity than patients with other mental disorders and evidence indicates that PROMs are sensitive to change and may be even better than clinician-rated measures at predicting treatment outcomes. Nonetheless, it should be noted that the measures reviewed lacked patient input in their development. Future research on PROMs must involve patient perspectives and include rigorous psychometric evaluation of these measures.
authors.affiliation: Research Division, Institute of Mental Health, Singapore.
authors.forename: Mythily
authors.initials: M
authors.lastname: Subramaniam
authors.affiliation: Research Division, Institute of Mental Health, Singapore.
authors.forename: Pauline
authors.initials: P
authors.lastname: Soh
authors.affiliation: Research Division, Institute of Mental Health, Singapore.
authors.forename: Clarissa
authors.initials: C
authors.lastname: Ong
authors.affiliation: Research Division, Institute of Mental Health, Singapore.
authors.forename: Lee Seng
authors.initials: LS
authors.lastname: Esmond Seow
authors.affiliation: Research Division, Institute of Mental Health, Singapore.
authors.forename: Louisa
authors.initials: L
authors.lastname: Picco
authors.affiliation: Research Division, Institute of Mental Health, Singapore.
authors.forename: Janhavi Ajit
authors.initials: JA
authors.lastname: Vaingankar
authors.affiliation: Research Division, Institute of Mental Health, Singapore.
authors.forename: Siow Ann
authors.initials: SA
authors.lastname: Chong
mesh_terms: D016208:Databases, Factual / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000523:psychology* / Q000628:therapy*; D063868:Patient Outcome Assessment; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life / Q000523:psychology*; D057566:Self Report
keywords: functioning; health-related quality of life; obsessive-compulsive disorder; patient-reported outcome; symptom