title: Effects of high thoracic epidural anesthesia on ischemic cardiomyopathy cardiac function and autonomic neural function.
abstract: We aimed at observing the effects of high thoracic epidural anesthesia (HTEA) on cardiac structure and function, heart rate variability (HRV), and QT interval variation (QTV) in ischemic cardiomyopathy (ICM) patients with chronic heart failure. We divided 30 ICM patients into HTEA (N = 16) and control (N = 14) groups.The control group was treated with medication, and the HTEA group was treated with HTEA and medication for 4 weeks. We measured the changes in the left-ventricular end-diastolic diameter (LVEDd) and left-ventricular ejection fraction (LVEF) before and after treatment by using echocardiography and examined changes in HRV and QTV using ambulatory electrocardiogram. HTEA significantly narrowed the LVEDd, improved LVEF, significantly increased the HRV, and significantly reduced the QTV in the ICM group compared to the control group. HTEA significantly narrowed the ventricular chamber diameter size of ICM patients, enhanced myocardial contractility, increased myocardial electrical stability, and improved the cardiac structure and function.
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Nangang District, Harbin, Heilongjiang, China.
authors.forename: X
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Nangang District, Harbin, Heilongjiang, China.
authors.forename: G Y
authors.initials: GY
authors.lastname: Chen
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Nangang District, Harbin, Heilongjiang, China yangshusen@medmail.com.
authors.forename: S S
authors.initials: SS
authors.lastname: Yang
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Nangang District, Harbin, Heilongjiang, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Tian
authors.affiliation: Department of Medical, Second Hospital of Harbin City, Harbin, Heilongjiang, China.
authors.forename: T
authors.initials: T
authors.lastname: Ge
authors.affiliation: Department of Medical, Second Hospital of Harbin City, Harbin, Heilongjiang, China.
authors.forename: H
authors.initials: H
authors.lastname: Qin
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Nangang District, Harbin, Heilongjiang, China.
authors.forename: W
authors.initials: W
authors.lastname: Han
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Nangang District, Harbin, Heilongjiang, China.
authors.forename: H Y
authors.initials: HY
authors.lastname: Chang
mesh_terms: D000328:Adult; D000368:Aged; D000767:Anesthesia, Epidural / Q000379:methods*; D001341:Autonomic Nervous System / Q000503:physiopathology*; D009202:Cardiomyopathies / Q000503:physiopathology*; D002908:Chronic Disease; D004452:Echocardiography / Q000379:methods; D005260:Female; D006321:Heart / Q000503:physiopathology; D006333:Heart Failure / Q000503:physiopathology; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000503:physiopathology*; D009206:Myocardium / Q000473:pathology; D016277:Ventricular Function, Left