title: Salvage liver transplantation for hepatocellular carcinoma recurrence after primary liver resection.
abstract: OBJECTIVE
  To evaluate the clinical efficacy and prognostic factors for salvage liver transplantation (SLT) for hepatocellular carcinoma (HCC) recurrence after primary liver resection.
  
  
  METHODS
  One hundred and eleven patients underwent SLT for HCC recurrence after primary liver resection from April 2000 to June 2011. We analyzed statistically the operative characteristics, survival rate, and effect of pathological characteristics on prognosis of SLT.
  
  
  RESULTS
  The overall survival rates at 6 months, and 1, 3 and 5 years after SLT were 87.9%, 75.5%, 56.3% and 49.1%, respectively. The mean age of the patients receiving SLT was 53.5 ± 9.6 years (range: 26.8-76.4 years), with a median follow-up of 28.8 months. The mean operating time was 10.34 ± 3.05 hours, and mean blood loss was 2925.0 ± 2373.51 ml. However, factors such as Edmondson grade, TNM stage, and invasion of hepatic and portal veins significantly affected the prognosis of SLT.
  
  
  CONCLUSIONS
  SLT for HCC recurrence after primary liver resection does not show increased surgery-related risks or reduced long-term survival rate, and thus SLT is an effective treatment for patients with HCC recurrence after primary liver resection.
authors.affiliation: Tianjin Medical University, 300070 Tianjin, PR China; Liver Transplant Section, Beijing Friendship Hospital, 100050 Beijing, PR China.
authors.forename: Wei
authors.initials: W
authors.lastname: Qu
authors.affiliation: Tianjin Medical University, 300070 Tianjin, PR China; Liver Transplant Section, Beijing Friendship Hospital, 100050 Beijing, PR China. Electronic address: fchzhuzhijun@hotmail.com.
authors.forename: Zhi-Jun
authors.initials: ZJ
authors.lastname: Zhu
authors.affiliation: Liver Transplant Section, Beijing Friendship Hospital, 100050 Beijing, PR China.
authors.forename: Li-Ying
authors.initials: LY
authors.lastname: Sun
authors.affiliation: Liver Transplant Section, Beijing Friendship Hospital, 100050 Beijing, PR China.
authors.forename: Lin
authors.initials: L
authors.lastname: Wei
authors.affiliation: Liver Transplant Section, Beijing Friendship Hospital, 100050 Beijing, PR China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Liver Transplant Section, Beijing Friendship Hospital, 100050 Beijing, PR China.
authors.forename: Zhi-Gui
authors.initials: ZG
authors.lastname: Zeng
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000401:mortality / Q000601:surgery*; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000601:surgery*; D011379:Prognosis; D012189:Retrospective Studies; D016879:Salvage Therapy; D015996:Survival Rate