title: The role of inflammation in the pathogenesis of macular edema secondary to retinal vascular diseases.
abstract: Macular edema (ME) is a nonspecific sign of numerous retinal vascular diseases. This paper is an updated overview about the role of inflammatory processes in the genesis of both diabetic macular edema (DME) and ME secondary to retinal vein occlusion (RVO). We focus on the inflammatory mediators implicated, the effect of the different intravitreal therapies, the recruitment of leukocytes mediated by adhesion molecules, and the role of retinal Müller glial (RMG) cells.
authors.affiliation: Department of Ophthalmology, "Lozano Blesa" University Clinic Hospital, San Juan Bosco 15, 50009 Zaragoza, Spain ; Aragon Health Sciences Institute, Zaragoza, Spain.
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Ascaso
authors.affiliation: Department of Ophthalmology, University Hospital Arnau de Vilanova, Lleida, Spain ; IRB-Lleida, Lleida, Spain.
authors.forename: Valentín
authors.identifier: 0000-0003-3832-6981
authors.initials: V
authors.lastname: Huerva
authors.affiliation: Department of Ophthalmology, Poznań City Hospital, Poznań, Poland ; University of Warmia and Mazury, Olsztyn, Poland.
authors.forename: Andrzej
authors.identifier: 0000-0002-3724-2391
authors.initials: A
authors.lastname: Grzybowski
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D006801:Humans; D007249:Inflammation / Q000188:drug therapy / Q000276:immunology / Q000473:pathology; D008269:Macular Edema / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology*; D012170:Retinal Vein Occlusion / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology*
chemical_list: D000893:Anti-Inflammatory Agents