title: Single-molecule trapping dynamics of sugar-uptake channels in marine bacteria.
abstract: Stochastic fluctuations of ion current through one chitoporin (ChiP) channel within a bilayer lipid membrane in sugar solution are analyzed. These reflect single-molecule dynamics, which indicate that ChiP has multiple binding sites for sugar and exploits interactions between bound molecules to direct sugar passage. Since ChiP is used by marine bacteria, this is likely an adaptive strategy to enhance sugar translocation from rough water.
authors.affiliation: Biochemistry-Electrochemistry Research Unit, Schools of Chemistry and Biochemistry, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
authors.forename: Wipa
authors.initials: W
authors.lastname: Suginta
authors.affiliation: School of Physics, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand and Thailand Center of Excellence in Physics (ThEP), Commission of Higher Education, Ministry of Education, Bangkok 10400, Thailand.
authors.forename: M F
authors.initials: MF
authors.lastname: Smith
mesh_terms: D001425:Bacterial Outer Membrane Proteins / Q000378:metabolism*; D050260:Carbohydrate Metabolism; D008051:Lipid Bilayers / Q000737:chemistry / Q000378:metabolism; D008954:Models, Biological; D056004:Molecular Dynamics Simulation; D018272:Porins / Q000378:metabolism*; D014733:Vibrio / Q000378:metabolism*
chemical_list: D001425:Bacterial Outer Membrane Proteins; D008051:Lipid Bilayers; D018272:Porins