title: Cognitive behavior therapy for obsessive-compulsive and related disorders.
abstract: Cognitive behavior therapy (CBT) is considered a first-line intervention for obsessive-compulsive disorder (OCD) across the lifespan. Efficacy studies of CBT with exposure and response prevention suggest robust symptom reduction, often with sustained remission. Acceptability of CBT is high, and the treatment is devoid of adverse side effects. The primary mechanism of CBT is based on operant principles, specifically extinction learning. The efficacy of extinction-based treatments such as CBT is being shown for other obsessive-compulsive spectrum disorders. This article reviews the theoretic basis, clinical application, and relevant treatment outcome research for CBT and related therapies for several obsessive-compulsive spectrum disorders.
authors.affiliation: Department of Pediatrics, Rothman Center for Neuropsychiatry, University of South Florida, 880 6th Street South, Suite 460, Box 7523, St Petersburg, FL 33701, USA; Department of Psychiatry and Behavioral Neurosciences, University of South Florida, 3515 East Fletcher Avenue, Tampa, FL 33616, USA; Department of Psychology, University of South Florida, 4202 East Fowler Avenue, PCD 4118G, Tampa, FL 33620, USA. Electronic address: alewin@health.usf.edu.
authors.forename: Adam B
authors.initials: AB
authors.lastname: Lewin
authors.affiliation: Department of Pediatrics, Rothman Center for Neuropsychiatry, University of South Florida, 880 6th Street South, Suite 460, Box 7523, St Petersburg, FL 33701, USA; Department of Psychology, University of South Florida, 4202 East Fowler Avenue, PCD 4118G, Tampa, FL 33620, USA.
authors.forename: Monica S
authors.initials: MS
authors.lastname: Wu
authors.affiliation: Department of Pediatrics, Rothman Center for Neuropsychiatry, University of South Florida, 880 6th Street South, Suite 460, Box 7523, St Petersburg, FL 33701, USA; Department of Psychology, University of South Florida, 4202 East Fowler Avenue, PCD 4118G, Tampa, FL 33620, USA.
authors.forename: Joseph F
authors.initials: JF
authors.lastname: McGuire
authors.affiliation: Department of Pediatrics, Rothman Center for Neuropsychiatry, University of South Florida, 880 6th Street South, Suite 460, Box 7523, St Petersburg, FL 33701, USA; Department of Psychiatry and Behavioral Neurosciences, University of South Florida, 3515 East Fletcher Avenue, Tampa, FL 33616, USA; Department of Psychology, University of South Florida, 4202 East Fowler Avenue, PCD 4118G, Tampa, FL 33620, USA.
authors.forename: Eric A
authors.initials: EA
authors.lastname: Storch
mesh_terms: D057215:Body Dysmorphic Disorders / Q000188:drug therapy / Q000523:psychology / Q000628:therapy*; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003131:Combined Modality Therapy; D006801:Humans; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy / Q000523:psychology* / Q000628:therapy*; D011619:Psychotropic Drugs / Q000627:therapeutic use; D012008:Recurrence; D005879:Tourette Syndrome / Q000188:drug therapy / Q000523:psychology / Q000628:therapy*; D014256:Trichotillomania / Q000188:drug therapy / Q000523:psychology / Q000628:therapy*
chemical_list: D011619:Psychotropic Drugs
keywords: CBT; Cognitive behavior therapy; Exposure therapy; OCD; Obsessive-compulsive disorder