title: Opaliferin, a new polyketide from cultures of entomopathogenic fungus Cordyceps sp. NBRC 106954.
abstract: Opaliferin, a polyketide with a unique partial structure in which a cyclopentanone and tetrahydrofuran were connected with an external double bond, was isolated from the insect pathogenic fungus Cordyceps sp. NBRC 106954. The structure and relative configuration of opaliferin were determined by spectroscopic analysis and X-ray crystallography. The absolute configuration was established by anomalous dispersion effects in X-ray diffraction measurements on the crystal of di(p-bromobenzoyl) ester of opaliferin. A plausible biosynthetic pathway for opaliferin is proposed.
authors.affiliation: Faculty of Pharmaceutical Sciences, Tokushima Bunri University , Yamashiro-cho, Tokushima 770-8514, Japan.
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Grudniewska
authors.forename: Sayaka
authors.initials: S
authors.lastname: Hayashi
authors.forename: Mina
authors.initials: M
authors.lastname: Shimizu
authors.forename: Masayuki
authors.initials: M
authors.lastname: Kato
authors.forename: Midori
authors.initials: M
authors.lastname: Suenaga
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Imagawa
authors.forename: Takuya
authors.initials: T
authors.lastname: Ito
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Asakawa
authors.forename: Sayaka
authors.initials: S
authors.lastname: Ban
authors.forename: Toshio
authors.initials: T
authors.lastname: Kumada
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Hashimoto
authors.forename: Akemi
authors.initials: A
authors.lastname: Umeyama
mesh_terms: D000818:Animals; D032661:Cordyceps / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006430:Hemiptera / Q000382:microbiology*; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D061065:Polyketides / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D061065:Polyketides; C000599275:opaliferin