title: Spontaneous intratumoral infarction--an unusual evolution of a falcine meningioma.
abstract: OBJECTIVE
  We report the incidence of spontaneous infarction of a falcine meningioma without preceding hemorrhage and shed light on the relation between intratumoral necrosis and hemorrhage.
  
  
  METHODS
  A 50 year-old woman presented with recurrent headaches and was found to harbor a falcine meningioma. The patient elected to observe the mass and 13 months later she developed new neurological deficits. Prior to scheduled resection, she presented with abdominal pain and underwent emergent laparoscopic cholecystectomy. Two days after the procedure, she developed sudden right hemiparesis associated with severe headache. MRI of the brain showed an intratumoral wedge-shaped hypointense area with significant peritumoral edema. The patient was started on high-dose corticosteroids with considerable improvement in strength.
  
  
  METHODS
  The patient underwent a complete resection of the tumor with no new neurological deficits post-operatively. Histopathological analysis confirmed a WHO grade II atypical meningioma with extensive necrosis without hemorrhage.
  
  
  CONCLUSIONS
  This case highlights that tumor infarction, although rare, should be in the differential diagnosis of patients with meningiomas presenting with new neurological deficits. When this condition is recognized and treated in timely manner with high-dose corticosteroids and surgical resection, patients can have favorable long-term outcomes.
authors.forename: Aakash
authors.initials: A
authors.lastname: Jain
authors.forename: Mark
authors.initials: M
authors.lastname: Hoeprich
authors.forename: Monika
authors.initials: M
authors.lastname: Mittal
authors.forename: William J
authors.initials: WJ
authors.lastname: Kupsky
authors.forename: Sandeep
authors.initials: S
authors.lastname: Mittal
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007238:Infarction / Q000175:diagnosis / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000473:pathology*; D008579:Meningioma / Q000175:diagnosis / Q000473:pathology*; D008875:Middle Aged; D009336:Necrosis / Q000473:pathology; D015173:Supratentorial Neoplasms / Q000175:diagnosis / Q000473:pathology