title: Anti-glycation and anti-oxidation properties of Capsicum frutescens and Curcuma longa fruits: possible role in prevention of diabetic complication.
abstract: The accumulation of advanced glycationend products (AGE's) in the body, due to the non-enzymatic glycation of proteins is associated with several pathological conditions like aging and diabetes mellitus. Hence a plant having anti-glycation and anti-oxidation potentials may serve as therapeutic agent for diabetic complications and aging. In this study the anti-glycation and anti-oxidation properties of crude methanolic extracts of fruits of Capsicum frutescens and Curcuma longa were investigated. Among the two C. frutescens had more anti-glycation ability with a minimum inhibitory concentration (MIC50) of 90βg/mLas compared to 324βg/mL MIC50 of C. longa. Curcuma longa had the more anti-oxidation potential i.e. 35.01, 30.83 and 28.08% at 0.5mg, 0.25mg and 0.125mg respectively.
authors.affiliation: Centre of Biotechnology and Microbiology, University of Peshawar, Khyber Pukhtoon Khwa, Pakistan.
authors.forename: Ibrar
authors.initials: I
authors.lastname: Khan
authors.affiliation: Centre of Biotechnology and Microbiology, University of Peshawar, Khyber Pukhtoon Khwa, Pakistan.
authors.forename: Haroon
authors.initials: H
authors.lastname: Ahmad
authors.affiliation: Centre of Biotechnology and Microbiology, University of Peshawar, Khyber Pukhtoon Khwa, Pakistan.
authors.forename: Bashir
authors.initials: B
authors.lastname: Ahmad
mesh_terms: D000975:Antioxidants / Q000494:pharmacology*; D002212:Capsicum; D030024:Curcuma; D048909:Diabetes Complications / Q000517:prevention & control*; D016166:Free Radical Scavengers / Q000494:pharmacology; D005638:Fruit; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology*
chemical_list: D000975:Antioxidants; D016166:Free Radical Scavengers; D007004:Hypoglycemic Agents; D010936:Plant Extracts