title: Palladium-catalyzed cyclization of benzamides with arynes: application to the synthesis of phenaglydon and N-methylcrinasiadine.
abstract: N-Methyl or methoxy benzamides reacted with benzynes in the presence of Pd(OAc)2, organic acid and K2S2O8 in CH3CN yielding tricyclic phenanthridinone derivatives in good yields.
authors.affiliation: Department of Chemistry, Indian Institute of Science Education and Research, Pune 411021, India. mjeganmohan@iiserpune.ac.in.
authors.forename: Sandeep
authors.initials: S
authors.lastname: Pimparkar
authors.forename: Masilamani
authors.initials: M
authors.lastname: Jeganmohan
mesh_terms: D000097:Acetonitriles / Q000737:chemistry; D001549:Benzamides / Q000737:chemistry*; D001555:Benzene Derivatives / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D010616:Phenanthrenes / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000097:Acetonitriles; D001549:Benzamides; D001555:Benzene Derivatives; D006576:Heterocyclic Compounds, 4 or More Rings; C507777:N-methylcrinasiadine; D010616:Phenanthrenes; C524146:benzyne; D010165:Palladium; C037689:benzamide; C040601:phenanthridone