title: [Giant cell tumour of bone: a series of 97 cases with a mean follow-up of 12 years].
abstract: OBJECTIVE
  To describe our series of patients with giant cell tumour of bone with a long-term follow-up to show the results obtained with our treatment protocol.
  
  
  METHODS
  A total of 97 histologically confirmed giant cell tumour of bone were treated in our center between 1982 and 2009. The mean follow-up period was 12 years (2-27 years). The treatment received was determined by the radiological grade based on the Campanacci classification. The series consisted of 53 women (54.6%) and 44 men (54.4%) with a median age of 34.16 years (15-71 years). The data collected was focused on the clinical presentation, location, phase, extension, recurrences, and complications.
  
  
  RESULTS
  The treatment most used in Campanacci grades i and ii was intralesional excision with high velocity drilling and filling with a graft. In grades iii that could not be treated with the aforementioned method, it was decided to perform en bloc resection. An overall recurrence rate of around 25.8% was observed. Seven cases (7.2%) presented with a recurrence of the malignancy. The death rate at the end of follow-up was 2.1% (2 cases).
  
  
  CONCLUSIONS
  Curettage with a high-velocity drill and a bone graft in giant cell tumour of bone Campanacci grades i and ii obtain good results after long-term follow-up. Some grade iii giant cell tumour of bone that cannot be treated with this therapeutic option require en bloc resection and reconstruction.
authors.affiliation: Servicio de Cirugía Ortopédica y Traumatología, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España.
authors.forename: F
authors.initials: F
authors.lastname: Abat
authors.affiliation: Servicio de Cirugía Ortopédica y Traumatología, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España.
authors.forename: M
authors.initials: M
authors.lastname: Almenara
authors.affiliation: Servicio de Cirugía Ortopédica y Traumatología, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España. Electronic address: apeiro@santpau.cat.
authors.forename: A
authors.initials: A
authors.lastname: Peiró
authors.affiliation: Servicio de Cirugía Ortopédica y Traumatología, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España.
authors.forename: L
authors.initials: L
authors.lastname: Trullols
authors.affiliation: Servicio de Anatomía Patológica, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España.
authors.forename: S
authors.initials: S
authors.lastname: Bagué
authors.affiliation: Servicio de Cirugía Ortopédica y Traumatología, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España.
authors.forename: I
authors.initials: I
authors.lastname: Grácia
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000401:mortality / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D018212:Giant Cell Tumor of Bone / Q000401:mortality / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult
keywords: Curettage; Giant cell tumour of bone; Legrado; Recurrence; Recurrencia; Tratamiento; Treatment; Tumor de células gigantes óseo