title: Prognostic factors related with survival in patients with pancreatic adenocarcinoma.
abstract: The prognosis in patients with pancreatic cancer is poor and this cancer is the fourth leading cause of cancer-related death worldwide. Although surgical resection is the only curative treatment of choice for pancreatic cancer, the majority of patients are diagnosed at an advanced stage, thus only 10%-15% of them are suitable for curative resection and the overall survival is less than 5%. Chemotherapy for metastatic disease is to palliate symptoms of patients and to improve survival. Therefore, prognostic factors are important and a correct definition of poor prognostic factors may help to guide more aggressive adjuvant or aggressive treatment protocols in patients with pancreatic cancer. This article reviews the prognostic factors affecting survival of patients with pancreatic cancer in the light of recent advances in the literature.
authors.affiliation: Ahmet Bilici, Department of Medical Oncology, Medical Faculty, Istanbul Medipol University, 34214 Bagcilar, Istanbul, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Bilici
mesh_terms: D000230:Adenocarcinoma / Q000097:blood / Q000235:genetics / Q000401:mortality / Q000556:secondary / Q000628:therapy*; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000097:blood / Q000235:genetics; D006801:Humans; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D010166:Palliative Care; D010180:Pancreatectomy / Q000009:adverse effects / Q000401:mortality; D010190:Pancreatic Neoplasms / Q000097:blood / Q000235:genetics / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D011237:Predictive Value of Tests; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor
keywords: Carbohydrate antigen 19-9; Pancreatic cancer; Prognostic factors; Survival; Treatment