title: LDK378 compassionate use for treating carcinomatous meningitis in an ALK translocated non-small-cell lung cancer.
authors.affiliation: *Institut Gustave Roussy; †Department of Radiology; ‡Department of Medical Oncology; and §Department of Medical Oncology, Gustave Roussy, Villejuif, France.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Arrondeau
authors.forename: Samy
authors.initials: S
authors.lastname: Ammari
authors.forename: Benjamin
authors.initials: B
authors.lastname: Besse
authors.forename: Jean-Charles
authors.initials: JC
authors.lastname: Soria
mesh_terms: D000328:Adult; D000077548:Anaplastic Lymphoma Kinase; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002289:Carcinoma, Non-Small-Cell Lung / Q000235:genetics* / Q000556:secondary; D057176:Compassionate Use Trials; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000235:genetics* / Q000473:pathology; D055756:Meningeal Carcinomatosis / Q000188:drug therapy* / Q000556:secondary; D011743:Pyrimidines / Q000627:therapeutic use*; D020794:Receptor Protein-Tyrosine Kinases / Q000235:genetics*; D013450:Sulfones / Q000627:therapeutic use*
chemical_list: D000970:Antineoplastic Agents; D011743:Pyrimidines; D013450:Sulfones; C000626173:ALK protein, human; D000077548:Anaplastic Lymphoma Kinase; D020794:Receptor Protein-Tyrosine Kinases; C586847:ceritinib