title: Magnetic resonance spectroscopy features of Heschl's gyri in patients with unilateral acoustic neuroma: preliminary study.
abstract: OBJECTIVE
  To evaluate neurochemical alterations in Heschl's gyri and determine the most affected side in case of unilateral acoustic neuroma using magnetic resonance spectroscopy (MRS).
  
  
  METHODS
  Fifteen patients with unilateral acoustic neuroma were studied. Following routine cranial MRI sequences, MRS of Heschl's gyri on tumor and nontumor sides was obtained. MRS metabolite values of both Heschl's gyri were statistically compared.
  
  
  RESULTS
  The values of N-acetylaspartate (NAA) and Cr on nontumor side Heschl's gyrus (HG) were significantly lower than that on tumor side.
  
  
  CONCLUSIONS
  We found nontumor side HG more affected with lower NAA and Cr values, suggesting neuronal damage and decreased energy metabolism compared to the tumoral side.
authors.affiliation: Department of Radiology, Bezmialem Vakif University School of Medicine, Vatan St, Aksaray, Istanbul, Turkey. Electronic address: rdr.kilicarslan@hotmail.com.
authors.forename: Rukiye
authors.initials: R
authors.lastname: Kilicarslan
authors.affiliation: Department of Radiology, Bezmialem Vakif University School of Medicine, Vatan St, Aksaray, Istanbul, Turkey.
authors.forename: Alpay
authors.initials: A
authors.lastname: Alkan
authors.affiliation: Department of Radiology, Bezmialem Vakif University School of Medicine, Vatan St, Aksaray, Istanbul, Turkey.
authors.forename: Ayse
authors.initials: A
authors.lastname: Aralasmak
authors.affiliation: Department of Otorhinolaryngology, Bezmialem Vakif University School of Medicine, Istanbul, Turkey.
authors.forename: Fadlullah
authors.initials: F
authors.lastname: Aksoy
authors.affiliation: Department of Radiology, Bezmialem Vakif University School of Medicine, Vatan St, Aksaray, Istanbul, Turkey.
authors.forename: Huseyin
authors.initials: H
authors.lastname: Toprak
authors.affiliation: Department of Radiology, Bezmialem Vakif University School of Medicine, Vatan St, Aksaray, Istanbul, Turkey.
authors.forename: Huseyin
authors.initials: H
authors.lastname: Yetis
authors.affiliation: Department of Otorhinolaryngology, Bezmialem Vakif University School of Medicine, Istanbul, Turkey.
authors.forename: Orhan
authors.initials: O
authors.lastname: Ozturan
mesh_terms: D001224:Aspartic Acid / Q000031:analogs & derivatives / Q000378:metabolism; D001303:Auditory Cortex / Q000033:anatomy & histology / Q000378:metabolism*; D015415:Biomarkers / Q000378:metabolism; D002794:Choline / Q000378:metabolism; D003401:Creatine / Q000378:metabolism; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D001224:Aspartic Acid; C000179:N-acetylaspartate; D003401:Creatine; D002794:Choline
keywords: Acoustic neuroma; MR spectroscopy