title: Oncological and functional outcomes of transoral surgery for the treatment of oropharyngeal cancer.
abstract: BACKGROUND
  Currently, most cases of oropharyngeal squamous cell carcinoma (OPSCC) are treated by chemoradiotherapy. However, serious concerns have arisen regarding toxicity and poor functional outcomes. Recently, transoral techniques for resection of selected OPSCC have been developed.
  
  
  OBJECTIVE
  To review the outcomes of transoral surgery for OPSCC at our institution.
  
  
  METHODS
  Retrospective review of 12 patients with OPSCC treated with transoral resection. Data on surgical complications, oncological outcomes, and functional outcomes were analysed.
  
  
  RESULTS
  Primary sites were tonsil (9), soft palate (1), base of tongue (1), and posterior pharyngeal wall (1). There were no surgical complications. After the mean follow-up of 19 months, there were no local or regional recurrences. Two patients (one with synchronous lung cancer) died from distant metastases. No patient required gastrostomy tube or had long-term speech or swallowing impairments.
  
  
  CONCLUSIONS
  Transoral resection is an excellent option for selected patients with OPSCC, offering excellent functional and oncological outcomes.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, South Infirmary Victoria University Hospital, Cork, Ireland.
authors.forename: P
authors.initials: P
authors.lastname: Chauhan
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, South Infirmary Victoria University Hospital, Cork, Ireland.
authors.forename: H
authors.initials: H
authors.lastname: Byrne
authors.affiliation: Department of Speech and Language Therapy, South Infirmary Victoria University Hospital, Cork, Ireland.
authors.forename: E
authors.initials: E
authors.lastname: Taylor
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, South Infirmary Victoria University Hospital, Cork, Ireland. sheahan.patrick@sivuh.ie.
authors.forename: P
authors.initials: P
authors.lastname: Sheahan
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009959:Oropharyngeal Neoplasms / Q000601:surgery*; D012189:Retrospective Studies
keywords: Human papilloma virus; Oropharynx cancer; Radiotherapy; Surgery; Transoral