title: Oligopeptide-decorated liquid crystal droplets for detecting proteases.
abstract: We prepared the bioactive liquid crystal (LC) droplets by decorating an oligopeptide at the LC/aqueous interface to stabilize the LC droplets. These LC droplets can be used to detect proteases through the specific cleavage of protease on an oligopeptide leading to a bipolar-to-radial transition of LC configuration inside the droplets.
authors.affiliation: Department of Chemistry, Tamkang University, New Taipei City 25137, Taiwan. chc@mail.tku.edu.tw.
authors.forename: Chung-Yun
authors.initials: CY
authors.lastname: Chang
authors.forename: Chih-Hsin
authors.initials: CH
authors.lastname: Chen
mesh_terms: D000595:Amino Acid Sequence; D002232:Carbocyanines / Q000737:chemistry; D002918:Chymotrypsin / Q000032:analysis / Q000378:metabolism; D005456:Fluorescent Dyes / Q000737:chemistry; D050866:Liquid Crystals / Q000737:chemistry*; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000737:chemistry* / Q000378:metabolism; D010447:Peptide Hydrolases / Q000032:analysis* / Q000378:metabolism; D013050:Spectrometry, Fluorescence
chemical_list: D002232:Carbocyanines; D005456:Fluorescent Dyes; D009842:Oligopeptides; C089187:cyanine dye 3; D010447:Peptide Hydrolases; D002918:Chymotrypsin; C117608:alpha-chymotrypsin