title: Lowered cutoff points of obesity indicators are better predictors of hypertension and diabetes mellitus in premenopausal Taiwanese women.
abstract: BACKGROUND
  In previous study, we found that in order to prevent MS in women aged <65 years, the cutoff points of obesity indicators should be lowered.
  
  
  OBJECTIVE
  To investigate whether our proposed cutoff points of obesity indicators predict the occurrence of hypertension (HT), diabetes mellitus (DM), and hyperlipidemia in premenopausal women with greater sensitivity and specificity compared to reference cutoff points of obesity that are currently being used.
  
  
  METHODS
  Using the database of the "2002 Survey on the Prevalence of Hypertension, Hyperglycemia and Hyperlipidemia in Taiwan" provided by the Bureau of Health Promotion, Taiwan as research material, data from 2270 premenopausal women aged 20-65 years were used for the analyses. The receiver-operating characteristic curves (ROC) of the body-mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) were used to predict HT, DM, and hyperlipidemia.
  
  
  RESULTS
  Obesity is not a good predictor of the occurrence of hyperlipidemia in premenopausal women aged <65 years. However, our proposed cutoff points had greater sensitivity and specificity than did the reference cutoff points. To prevent the risk of HT and DM in premenopausal women, the cutoff points of obesity indicators should be reduced. The proposed values are as follows: a WHR of 0.79; a WC of 74.7 cm; a WHtR of 0.49; and a BMI of 22.3 kg/m(2).
authors.affiliation: Chang Gung University of Science and Technology, Taoyuan, Taiwan; Graduate Institute of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.
authors.forename: Fu-Ling
authors.initials: FL
authors.lastname: Chu
authors.affiliation: School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, Taiwan.
authors.forename: Chung-Huei
authors.initials: CH
authors.lastname: Hsu
authors.affiliation: Graduate Institute of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan. Electronic address: chii@tmu.edu.tw.
authors.forename: Chii
authors.initials: C
authors.lastname: Jeng
mesh_terms: D000328:Adult; D019540:Area Under Curve; D015415:Biomarkers; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology* / Q000517:prevention & control; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology; D006973:Hypertension / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology; D008875:Middle Aged; D009765:Obesity / Q000150:complications* / Q000453:epidemiology / Q000503:physiopathology; D015995:Prevalence; D012372:ROC Curve; D012016:Reference Values; D012680:Sensitivity and Specificity; D013624:Taiwan / Q000453:epidemiology; D055105:Waist Circumference; D065927:Waist-Height Ratio; D049629:Waist-Hip Ratio; D016387:Women's Health
chemical_list: D015415:Biomarkers
keywords: Diabetes; Hypertension; Obesity indicators; Women