title: Across-shift changes of exhaled nitric oxide and spirometric indices among cotton textile workers.
abstract: OBJECTIVE
  For the purpose of evaluation of exhaled NO as an index of airway inflammation, we assessed changes in fractional exhaled NO (FeNO) across a work shift and its relationship with respiratory complaints.
  
  
  METHODS
  Chronic and work-aggravated respiratory complaints were assessed using a questionnaire in 89 male textile workers. FeNO and spirometry were performed before and after a work shift and all the changes were registered.
  
  
  RESULTS
  A significant increase in FeNO after a work shift was observed. Post-shift FeNO was significantly higher among the subjects with chronic respiratory complaints. There was an obvious decrease in FVC, and FEV1 after a work shift; however, we couldn't find a significant relationship between changes in respiratory parameters and concentration of inhalable dusts.
  
  
  CONCLUSIONS
  FeNO increase after a work shift along with pulmonary function decrement and higher post-shift FeNO among subjects with respiratory complaints makes across-shift FeNO a non-invasive test for assessment of airway hyper-responsiveness in textile workers.
authors.affiliation: Department of Occupational Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
authors.forename: Seyed Jalil
authors.initials: SJ
authors.lastname: Mirmohammadi
authors.forename: Amir Houshang
authors.initials: AH
authors.lastname: Mehrparvar
authors.forename: Sara
authors.initials: S
authors.lastname: Safaei
authors.forename: Mojahede Salmani
authors.initials: MS
authors.lastname: Nodoushan
authors.forename: Mona Torab
authors.initials: MT
authors.lastname: Jahromi
mesh_terms: D000293:Adolescent; D000328:Adult; D032561:Cotton Fiber; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D009569:Nitric Oxide / Q000378:metabolism*; D012130:Respiratory Hypersensitivity / Q000378:metabolism* / Q000503:physiopathology*; D013147:Spirometry; D011795:Surveys and Questionnaires; D013783:Textile Industry
chemical_list: D009569:Nitric Oxide