title: Physiology of sleep and breathing before and after lung transplantation.
abstract: During the past 20 years, lung transplantation (LTX) has evolved and it is now accepted as a mainstream modality for care of patients with severe life-threatening respiratory diseases that are refractory to maximal conventional therapies. Improvements in surgical techniques and in antirejection medications have resulted in prolonged survival in these patients. Several studies have explored quality of life after LTX and its improvement has been noted especially in the early period between 3 and 6 months. This article discusses the salient features of the physiology of breathing and sleep disturbances before and after LTX and its alterations during sleep.
authors.affiliation: Lung Transplant Unit, St Vincents Hospital, 390 Victoria Street, Darlinghurst, Sydney 2010, Australia.
authors.forename: Paola
authors.initials: P
authors.lastname: Pierucci
authors.affiliation: Lung Transplant Unit, St Vincents Hospital, 390 Victoria Street, Darlinghurst, Sydney 2010, Australia. Electronic address: mmalouf@stvincents.com.au.
authors.forename: Monique
authors.initials: M
authors.lastname: Malouf
mesh_terms: D002318:Cardiovascular Diseases / Q000453:epidemiology; D015897:Comorbidity; D003550:Cystic Fibrosis / Q000503:physiopathology; D005764:Gastroesophageal Reflux / Q000453:epidemiology / Q000503:physiopathology; D006801:Humans; D016040:Lung Transplantation / Q000379:methods; D012131:Respiratory Insufficiency / Q000503:physiopathology* / Q000601:surgery; D012890:Sleep / Q000502:physiology*; D012891:Sleep Apnea Syndromes / Q000503:physiopathology*; D014850:Waiting Lists; D015430:Weight Gain / Q000502:physiology
keywords: CSA; Lung transplant; OSA; SDB; Sleep disorders