title: Correlation between collateral ventilation and interlobar lung fissures.
abstract: BACKGROUND
  New bronchoscopic techniques for end-stage emphysema treatment are nowadays available; the presence of interlobar collateral ventilation (CV) and interlobar lung fissures (ILF) is crucial for patient selection.
  
  
  OBJECTIVE
  Assessment of these variables has been reported previously, but it has never been anatomically validated in vivo. This is the purpose of our study.
  
  
  METHODS
  Twenty-one patients undergoing lung resection for lung cancer were prospectively enrolled in this study. At operation, CV was assessed by the Chartis catheter system. ILF completeness at high-resolution computed tomography (HRCT) was retrospectively reviewed. The ILF status at HRCT and at surgery was compared; furthermore, the relationship between CV and ILF status was assessed.
  
  
  RESULTS
  At HRCT, ILF were incomplete in 18 cases; at catheter evaluation, CV was present in 11 cases; 15 patients had incomplete ILF at operation. HRCT specificity, sensitivity and accuracy were 33, 93 and 76% compared with ILF status at surgery. HRCT accuracy was 90% on the right and 63% on the left. We demonstrated a high grade of probability of CV presence and incomplete ILF at surgery (odds ratio = 10.0).
  
  
  CONCLUSIONS
  There is a correlation between ILF status and CV. Both catheter evaluation of CV and HRCT assessment of ILF show some limitations. However, the cumulative information provided by these techniques allows to reliably assess the anatomical ILF status.
authors.affiliation: Department of Thoracic Surgery, University of Rome Sapienza, Rome, Italy.
authors.forename: Daniele
authors.initials: D
authors.lastname: Diso
authors.forename: Marco
authors.initials: M
authors.lastname: Anile
authors.forename: Carolina
authors.initials: C
authors.lastname: Carillo
authors.forename: Franco
authors.initials: F
authors.lastname: Ruberto
authors.forename: Miriam
authors.initials: M
authors.lastname: Patella
authors.forename: Emanuele
authors.initials: E
authors.lastname: Russo
authors.forename: Francesco
authors.initials: F
authors.lastname: Fraioli
authors.forename: Tiziano
authors.initials: T
authors.lastname: De Giacomo
authors.forename: Sara
authors.initials: S
authors.lastname: Mantovani
authors.forename: Erino
authors.initials: E
authors.lastname: Rendina
authors.forename: Federico
authors.initials: F
authors.lastname: Venuta
mesh_terms: D000368:Aged; D001999:Bronchoscopy / Q000379:methods; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology / Q000503:physiopathology; D008175:Lung Neoplasms / Q000601:surgery; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D011013:Pneumonectomy / Q000379:methods*; D011656:Pulmonary Emphysema / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D012123:Pulmonary Ventilation; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D013223:Statistics as Topic; D014057:Tomography, X-Ray Computed / Q000379:methods