title: Psychotropic drug use in a cohort of workers 4 years after an industrial disaster in France.
abstract: Two years after the 2001 Toulouse industrial disaster, a longitudinal study was set up to evaluate the impact of the disaster. The current substudy examines the medium-term impact (5 years) the incident had on the mental health of 3,004 participants. As part of the monitoring, data relating to the psychotropic drug use of 2,494 participants were collected from administrative databases 4 years after the disaster. Use of psychotropics was higher among women for anxiolytics (10.4% for men and 15.0% for women), hypnotics (10.5% and 17.0%), and antidepressants (7.6% and 11.2%). Exposure to the disaster, especially proximity to the exposure, was significantly associated with the use of antidepressants in men, OR = 3.22, 95% CI[1.57, 6.61]. This was also the case for other exposure factors (saw dead or injury, injured, home damage, death or injury loved one, psychological disorders, exposure toxic fumes): range of OR 1.75 to 2.52 in men, 1.48 to 1.62 in women. In conclusion, this study highlights the medium-term psychological impact of an industrial disaster on psychotropic drug use and the potential for using medical records data as a means for tracking postdisaster mental health.
authors.affiliation: Institut de Veille Sanitaire (InVS), Saint-Maurice, France.
authors.forename: Eloi
authors.initials: E
authors.lastname: Diène
authors.forename: Béatrice
authors.initials: B
authors.lastname: Geoffroy-Perez
authors.forename: Christine
authors.initials: C
authors.lastname: Cohidon
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Gauvin
authors.forename: Matthieu
authors.initials: M
authors.lastname: Carton
authors.forename: Aurélie
authors.initials: A
authors.lastname: Fouquet
authors.forename: Jean-Yves
authors.initials: JY
authors.lastname: Fatras
authors.forename: Ellen
authors.initials: E
authors.lastname: Imbernon
mesh_terms: D000062:Accidents, Occupational / Q000523:psychology*; D000328:Adult; D014151:Anti-Anxiety Agents / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000627:therapeutic use; D002617:Chemical Industry; D016208:Databases, Factual; D004363:Drug Utilization / Q000706:statistics & numerical data*; D005107:Explosions; D005260:Female; D005602:France; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D008137:Longitudinal Studies; D008297:Male; D054527:Mass Casualty Incidents / Q000523:psychology*; D008875:Middle Aged; D011619:Psychotropic Drugs / Q000627:therapeutic use*; D012737:Sex Factors; D011795:Surveys and Questionnaires
chemical_list: D014151:Anti-Anxiety Agents; D000928:Antidepressive Agents; D006993:Hypnotics and Sedatives; D011619:Psychotropic Drugs