title: Ethinylestradiol + cyproterone: back in France for acne and hirsutism, despite frequent off-label prescription.
abstract: Following a European review, products containing the ethinylestradiol + cyproterone combination are back on the French market for women with acne (as second-line treatment) or hirsutism. Yet experience has shown that frequent off-label prescription of this combination for contraceptive purposes exposes many women to an unjustified risk of thromboembolism.
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy*; D003534:Cyproterone / Q000008:administration & dosage / Q000009:adverse effects*; D004997:Ethinyl Estradiol / Q000008:administration & dosage / Q000009:adverse effects*; D006628:Hirsutism / Q000188:drug therapy*; D006801:Humans; D056687:Off-Label Use; D013923:Thromboembolism / Q000139:chemically induced
chemical_list: D004997:Ethinyl Estradiol; D003534:Cyproterone