title: A study of microemboli monitoring of atherosclerotic thrombotic cerebral infarction and artery stenosis.
abstract: This study aimed to assess the relationship between the recurrence and prognosis of patients with acute middle cerebral artery infarction, atherosclerotic brain infarction, and the existence of microemboli. We continuously enrolled patients with acute atherosclerotic thrombotic cerebral infarction artery stenosis. We performed transcranial Doppler color ultrasound micro emboli monitoring, color Doppler ultrasound carotid artery tests, intracranial and carotid artery magnetic resonance angiography, impairment evaluation of nerve function, and registration of stroke recurrence and stroke mortality. Of the 49 patients enrolled in the study, 123 main arteries presented atherosclerotic stenosis or formed plaques, and 33 patients had symptomatic stenosis. Patients with symptomatic stenosis have a higher incidence of microemboli than patients with asymptomatic stenosis (P = 0.009). The microembolus-positive rate increased in patients with unstable plaques (P = 0.001). Patients who were microembolus-negative were more likely to show a neural function deficient NIHSS (National Institutes of Stroke Scale) score improvement than patients who were microembolus-positive at one week (P = 0.026). However, we found no significant difference between mRS (modified rankin scale) score (P = 0.319), relapse, and death (P = 0.179). The rate of microembolus-positivity increased in patients with atherosclerotic thrombotic cerebral infarction and unstable plaques. Patients who were microembolus-negative were more likely to show an improvement of neural function deficiency than patients with microembolus-positivity at one week (P = 0.026).
authors.affiliation: Department of Neurology, LianyunGang Second People's Hospital (Bengbu Medical College, Lianyungang Hospital), District Xinpu, LianyunGang, China.
authors.forename: D J
authors.initials: DJ
authors.lastname: Sun
authors.affiliation: Department of Neurology, LianyunGang Second People's Hospital (Bengbu Medical College, Lianyungang Hospital), District Xinpu, LianyunGang, China.
authors.forename: A X
authors.initials: AX
authors.lastname: Zhuang
authors.affiliation: Department of Neurology, LianyunGang Second People's Hospital (Bengbu Medical College, Lianyungang Hospital), District Xinpu, LianyunGang, China.
authors.forename: Q H
authors.initials: QH
authors.lastname: Zeng
authors.affiliation: Department of Neurology, LianyunGang Second People's Hospital (Bengbu Medical College, Lianyungang Hospital), District Xinpu, LianyunGang, China.
authors.forename: Y L
authors.initials: YL
authors.lastname: Jiang
authors.affiliation: Department of Neurology, LianyunGang Second People's Hospital (Bengbu Medical College, Lianyungang Hospital), District Xinpu, LianyunGang, China jiandongjiang@yeah.net.
authors.forename: J D
authors.initials: JD
authors.lastname: Jiang
authors.affiliation: Neurological Examination Division, LianyunGang Second People's Hospital (Bengbu Medical College, Lianyungang Hospital), District Xinpu, LianyunGang, China.
authors.forename: S Q
authors.initials: SQ
authors.lastname: Feng
authors.affiliation: Department of Radiology, LianyunGang Second People's Hospital (Bengbu Medical College, Lianyungang Hospital), District Xinpu, LianyunGang, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Ultrasound, LianyunGang Second People's Hospital (Bengbu Medical College, Lianyungang Hospital), District Xinpu, LianyunGang, China.
authors.forename: H M
authors.initials: HM
authors.lastname: Huang
authors.affiliation: Department of Neurology, LianyunGang Second People's Hospital (Bengbu Medical College, Lianyungang Hospital), District Xinpu, LianyunGang, China.
authors.forename: H X
authors.initials: HX
authors.lastname: Nie
authors.affiliation: Department of Neurology, LianyunGang Second People's Hospital (Bengbu Medical College, Lianyungang Hospital), District Xinpu, LianyunGang, China.
authors.forename: L
authors.initials: L
authors.lastname: Liu
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D002339:Carotid Arteries / Q000000981:diagnostic imaging; D002539:Cerebral Arterial Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging*; D003251:Constriction, Pathologic / Q000175:diagnosis / Q000000981:diagnostic imaging; D004617:Embolism / Q000175:diagnosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000175:diagnosis / Q000000981:diagnostic imaging*; D002537:Intracranial Arteriosclerosis / Q000175:diagnosis / Q000000981:diagnostic imaging*; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination / Q000379:methods; D011379:Prognosis; D012008:Recurrence; D012307:Risk Factors; D020521:Stroke / Q000175:diagnosis; D017585:Ultrasonography, Doppler, Transcranial / Q000379:methods*