title: Acute kidney injury in the neonate.
abstract: Critically ill neonates are at risk for acute kidney injury (AKI). AKI has been associated with increased risk of morbidity and mortality in adult and pediatric patients, and increasing evidence suggests a similar association in the neonatal population. This article describes the current AKI definitions (including their limitations), work on novel biomarkers to define AKI, diagnosis and management strategies, long-term outcomes after AKI, and future directions for much-needed research in this important area.
authors.affiliation: Division of Nephrology, Dialysis and Transplantation, University of Iowa Children's Hospital, 200 Hawkins Drive, 4023 BT, Iowa City, IA 52242, USA.
authors.forename: Jennifer G
authors.initials: JG
authors.lastname: Jetton
authors.affiliation: Division of Pediatric Nephrology, University of Alabama at Birmingham, 1600 7th Avenue South, Lowder Building 516, Birmingham, AL 35233, USA. Electronic address: daskenazi@peds.uab.edu.
authors.forename: David J
authors.initials: DJ
authors.lastname: Askenazi
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D016638:Critical Illness; D003937:Diagnosis, Differential; D019468:Disease Management; D014943:Global Health; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D012307:Risk Factors
keywords: Acute kidney injury; Acute renal failure; Biomarkers; Chronic kidney disease; Critical illness; Neonate