title: Cutting through the noise: the mechanics of intracellular transport.
abstract: Intracellular transport of organelles and proteins is driven by multiple ATP-dependent processes. Recently in Cell, Guo et al. (2014) developed a technique, force-spectrum microscopy, to measure intracellular forces and demonstrate that large motion of cellular components can be produced by random ATP-dependent fluctuations within the cytoplasm.
authors.affiliation: Biophysical Sciences Graduate Program, University of Chicago, Chicago, IL 60637, USA; James Franck Institute and Institute for Biophysical Dynamics, University of Chicago, Chicago, IL 60637, USA.
authors.forename: Samantha
authors.initials: S
authors.lastname: Stam
authors.affiliation: James Franck Institute and Institute for Biophysical Dynamics, University of Chicago, Chicago, IL 60637, USA; Department of Physics, University of Chicago, Chicago, IL 60637, USA. Electronic address: gardel@uchicago.edu.
authors.forename: Margaret L
authors.initials: ML
authors.lastname: Gardel
mesh_terms: D000818:Animals; D003593:Cytoplasm / Q000737:chemistry*; D018625:Microscopy, Atomic Force / Q000379:methods*