title: Lung perfusion imaging in hepatopulmonary syndrome using (99m)Tc macroaggregated albumin.
abstract: Hepatopulmonary syndrome is a serious pulmonary vascular complication in patients with chronic liver disease. It constitutes a triad of chronic liver disease, increased alveolar-arterial oxygen gradient, and evidence of intrapulmonary shunt (IPS). The diagnosis of IPS can be made by bubble echocardiography, technetium-99m-labeled macroaggregated albumin ((99m)Tc-MAA) scintigraphy or pulmonary arteriography. Though echocardiography is a sensitive screening test, MAA scintigraphy can also quantify the extent of shunting.
authors.affiliation: Department of Radiology, The University of Alabama at Birmingham, Birmingham, AL, USA, dsurasi@uabmc.edu.
authors.forename: Devaki Shilpa
authors.initials: DS
authors.lastname: Surasi
authors.forename: Padma
authors.initials: P
authors.lastname: Manapragada
authors.forename: Pradeep
authors.initials: P
authors.lastname: Bhambhvani
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging; D004417:Dyspnea; D004452:Echocardiography; D005260:Female; D020065:Hepatopulmonary Syndrome / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging; D008107:Liver Diseases / Q000000981:diagnostic imaging; D008168:Lung / Q000000981:diagnostic imaging*; D008875:Middle Aged; D065626:Non-alcoholic Fatty Liver Disease / Q000000981:diagnostic imaging; D010100:Oxygen; D010477:Perfusion; D055420:Perfusion Imaging / Q000379:methods*; D019275:Radiopharmaceuticals / Q000737:chemistry; D013438:Sulfhydryl Compounds / Q000737:chemistry*; D013668:Technetium Tc 99m Aggregated Albumin / Q000737:chemistry*
chemical_list: D019275:Radiopharmaceuticals; D013438:Sulfhydryl Compounds; D013668:Technetium Tc 99m Aggregated Albumin; C082426:technetium Tc99m-mercaptoacetyl albumin; D010100:Oxygen