title: Synthesis, spectral characterization, and biological evaluation of transition metal complexes of bidentate N, o donor schiff bases.
abstract: New series of three bidentate N, O donor type Schiff bases (L (1) )-(L (3) ) were prepared by using ethylene-1,2-diamine with 5-methyl furfural, 2-anisaldehyde, and 2-hydroxybenzaldehyde in an equimolar ratio. These ligands were further complexed with Co(II), Cu(II), Ni(II), and Zn(II) metals to produce their new metal complexes having an octahedral geometry. These compounds were characterized on the basis of their physical, spectral, and analytical data. Elemental analysis and spectral data of the uncomplexed ligands and their metal(II) complexes were found to be in good agreement with their structures, indicating high purity of all the compounds. All ligands and their metal complexes were screened for antimicrobial activity. The results of antimicrobial activity indicated that metal complexes have significantly higher activity than corresponding ligands. This higher activity might be due to chelation process which reduces the polarity of metal ion by coordinating with ligands.
authors.affiliation: Department of Chemistry, Institute of Chemical and Biological Sciences, University of Gujrat, Gujrat 50700, Pakistan.
authors.forename: Sajjad Hussain
authors.initials: SH
authors.lastname: Sumrra
authors.affiliation: Department of Applied Chemistry, Government College University, Faisalabad 38000, Pakistan.
authors.forename: Muhammad
authors.identifier: 0000-0003-1672-8955
authors.initials: M
authors.lastname: Ibrahim
authors.affiliation: Department of Chemistry, University of Karachi, Karachi 75270, Pakistan.
authors.forename: Sabahat
authors.initials: S
authors.lastname: Ambreen
authors.affiliation: Department of Chemistry, Government Emerson College, Multan 60700, Pakistan.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Imran
authors.affiliation: Department of Chemistry, Institute of Chemical and Biological Sciences, University of Gujrat, Gujrat 50700, Pakistan.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Danish
authors.affiliation: Department of Chemistry, University of Karachi, Karachi 75270, Pakistan.
authors.forename: Fouzia Sultana
authors.initials: FS
authors.lastname: Rehmani