title: Clinical predictive criteria associated with live birth following elective single embryo transfer.
abstract: OBJECTIVE
  We aimed to define clinical criteria from the patients related to the occurrence of live birth in case of elective single embryo transfer (eSET).
  
  
  METHODS
  We analyzed retrospectively 409 eSET at day 2/3 between March 2005 and July 2012, proposed in case of (i) woman's age <37 years, (ii) first/second IVF0 cycle, (iii) ≥2 good quality embryos obtained (3-5/6-10 blastomeres at day 2/3 and <20% fragmentation), including one top embryo (4/8 cells). In all, 124/409 live births (30.3%) were obtained, separating patients into groups of women who had birth or not. Different clinical parameters of interest were compared between each group, using appropriate statistical tests at p<0.05 significance level.
  
  
  RESULTS
  By comparing Body Mass Index (BMI), we report a statistically higher BMI among women who did not deliver (24.6 vs. 23.4kg/m(2); p=0.014). Using an analysis by BMI categories, we also precise a threshold of BMI≥30kg/m(2), negatively associated with the occurrence of live birth.
  
  
  CONCLUSIONS
  BMI appears to be the only clinical parameter statistically associated with delivery following eSET strategy in a good prognosis infertile population.
authors.affiliation: Service d'Histologie-Embryologie-Cytogénétique-CECOS, Centre Hospitalier Universitaire Jean Verdier, Assistance Publique - Hôpitaux de Paris, Avenue du 14 Juillet, 93140 Bondy, France; Université Paris 13, Sorbonne Paris Cité, Unité de Recherche en Epidémiologie Nutritionnelle, UMR U557 Inserm, U1125 Inra, Cnam, CRNH IdF, 93017 Bobigny, France. Electronic address: christophe.sifer@jvr.aphp.fr.
authors.forename: Christophe
authors.initials: C
authors.lastname: Sifer
authors.affiliation: Service d'Histologie-Embryologie-Cytogénétique-CECOS, Centre Hospitalier Universitaire Jean Verdier, Assistance Publique - Hôpitaux de Paris, Avenue du 14 Juillet, 93140 Bondy, France.
authors.forename: Charlène
authors.initials: C
authors.lastname: Herbemont
authors.affiliation: Service de Médecine de la Reproduction, Centre Hospitalier Universitaire Jean Verdier, Assistance Publique - Hôpitaux de Paris, Avenue du 14 Juillet, 9340 Bondy, France.
authors.forename: Elodie
authors.initials: E
authors.lastname: Adda-Herzog
authors.affiliation: Service d'Histologie-Embryologie-Cytogénétique-CECOS, Centre Hospitalier Universitaire Jean Verdier, Assistance Publique - Hôpitaux de Paris, Avenue du 14 Juillet, 93140 Bondy, France; Université Paris 13, Sorbonne Paris Cité, Unité de Recherche en Epidémiologie Nutritionnelle, UMR U557 Inserm, U1125 Inra, Cnam, CRNH IdF, 93017 Bobigny, France.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Sermondade
authors.affiliation: Service d'Histologie-Embryologie-Cytogénétique-CECOS, Centre Hospitalier Universitaire Jean Verdier, Assistance Publique - Hôpitaux de Paris, Avenue du 14 Juillet, 93140 Bondy, France; Université Paris 13, Sorbonne Paris Cité, Unité de Recherche en Epidémiologie Nutritionnelle, UMR U557 Inserm, U1125 Inra, Cnam, CRNH IdF, 93017 Bobigny, France.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Dupont
authors.affiliation: Service de Médecine de la Reproduction, Centre Hospitalier Universitaire Jean Verdier, Assistance Publique - Hôpitaux de Paris, Avenue du 14 Juillet, 9340 Bondy, France.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Cedrin-Durnerin
authors.affiliation: Service de Médecine de la Reproduction, Centre Hospitalier Universitaire Jean Verdier, Assistance Publique - Hôpitaux de Paris, Avenue du 14 Juillet, 9340 Bondy, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Poncelet
authors.affiliation: Service d'Histologie-Embryologie-Cytogénétique-CECOS, Centre Hospitalier Universitaire Jean Verdier, Assistance Publique - Hôpitaux de Paris, Avenue du 14 Juillet, 93140 Bondy, France; Université Paris 13, Sorbonne Paris Cité, Unité de Recherche en Epidémiologie Nutritionnelle, UMR U557 Inserm, U1125 Inra, Cnam, CRNH IdF, 93017 Bobigny, France.
authors.forename: Rachel
authors.initials: R
authors.lastname: Levy
authors.affiliation: Service de Médecine de la Reproduction, Centre Hospitalier Universitaire Jean Verdier, Assistance Publique - Hôpitaux de Paris, Avenue du 14 Juillet, 9340 Bondy, France.
authors.forename: Michael
authors.initials: M
authors.lastname: Grynberg
authors.affiliation: Service de Médecine de la Reproduction, Centre Hospitalier Universitaire Jean Verdier, Assistance Publique - Hôpitaux de Paris, Avenue du 14 Juillet, 9340 Bondy, France.
authors.forename: Jean-Noël
authors.initials: JN
authors.lastname: Hugues
mesh_terms: D000328:Adult; D015992:Body Mass Index; D005260:Female; D006801:Humans; D007246:Infertility / Q000628:therapy; D050498:Live Birth; D008297:Male; D011247:Pregnancy; D018873:Pregnancy Rate; D011379:Prognosis; D012189:Retrospective Studies; D056826:Single Embryo Transfer; D020554:Sperm Injections, Intracytoplasmic
keywords: Elective single embryo transfer; IVF/ICSI; Live birth; Predictive parameters