title: Blood Type O is not associated with increased blood loss in extensive spine surgery.
abstract: OBJECTIVE
  To investigate whether Type O blood group status is associated with increased intraoperative blood loss and requirement of blood transfusion in extensive spine surgery.
  
  
  METHODS
  Retrospective comparative study.
  
  
  METHODS
  University-affiliated, non-profit teaching hospital.
  
  
  METHODS
  Data from 1,050 ASA physical status 1, 2, 3, 4, and 5 patients who underwent spine surgeries involving 4 or more vertebral levels were analyzed. Patients with Type O blood were matched to similar patients with other blood types using propensity scores, which were estimated via demographic and morphometric data, medical history variables, and extent of surgery. Intraoperative estimated blood loss (EBL) was compared among matched patients using a linear regression model; intraoperative transfusion requirement in volume of red blood cells, fresh frozen plasma, platelet, cryoprecipitate, cell salvaged blood, volume of intraoperative infusion of hetastarch, 5% albumin, crystalloids, and hospital length of hospital (LOS) were compared using Wilcoxon rank-sum tests.
  
  
  RESULTS
  Intraoperative EBL and requirement of blood product transfusion were similar in patients with Type O blood group and those with other blood groups.
  
  
  CONCLUSIONS
  There was no association between Type O blood and increased intraoperative blood loss or blood transfusion requirement during extensive spine surgery, with similar hospital LOS in Type O and non-O patients.
authors.affiliation: Anesthesiology Institute, Cleveland Clinic, 9500 Euclid Ave.,/E30, Cleveland, OH, 44195 USA. Electronic address: komatsr@ccf.org.
authors.forename: Ryu
authors.initials: R
authors.lastname: Komatsu
authors.affiliation: Department of Quantitative Health Sciences, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA; Department of OUTCOMES RESEARCH, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.
authors.forename: Jarrod E
authors.initials: JE
authors.lastname: Dalton
authors.affiliation: Department of OUTCOMES RESEARCH, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Ghobrial
authors.affiliation: Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
authors.forename: Alexander Y
authors.initials: AY
authors.lastname: Fu
authors.affiliation: Department of OUTCOMES RESEARCH, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.
authors.forename: Jae H
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Department of OUTCOMES RESEARCH, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.
authors.forename: Cameron
authors.initials: C
authors.lastname: Egan
authors.affiliation: Department of OUTCOMES RESEARCH, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.
authors.forename: Daniel I
authors.initials: DI
authors.lastname: Sessler
authors.affiliation: Department of Anesthesiology, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Kasuya
authors.affiliation: Department of OUTCOMES RESEARCH, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.
authors.forename: Alparslan
authors.initials: A
authors.lastname: Turan
mesh_terms: D000017:ABO Blood-Group System; D000328:Adult; D000368:Aged; D016913:Blood Component Transfusion / Q000379:methods; D016063:Blood Loss, Surgical / Q000706:statistics & numerical data*; D004198:Disease Susceptibility / Q000097:blood; D005260:Female; D006801:Humans; D007430:Intraoperative Care / Q000379:methods; D008297:Male; D008875:Middle Aged; D057216:Propensity Score; D012189:Retrospective Studies; D012307:Risk Factors; D013131:Spine / Q000601:surgery*
chemical_list: D000017:ABO Blood-Group System
keywords: Blood loss, surgical; Blood salvage, intraoperative; Hemodilution; Transfusion; Type O blood