title: Cancer gene discovery goes mobile.
abstract: A new study describes a tool, Lentihop, for somatic insertional mutagenesis in human cells and uses this system in combination with cancer genome data to define new genes and pathways involved in sarcoma development. Gene discovery in this way suggests that we are far from a complete catalog of cancer drivers.
authors.affiliation: Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.
authors.forename: Louise
authors.initials: L
authors.lastname: van der Weyden
authors.affiliation: Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.
authors.forename: Marco
authors.initials: M
authors.lastname: Ranzani
authors.affiliation: Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.
authors.forename: David J
authors.initials: DJ
authors.lastname: Adams
mesh_terms: D006801:Humans; D016254:Mutagenesis, Insertional; D012509:Sarcoma / Q000235:genetics*