title: 5-Amino-5'-bromo-6-(4-methyl-benzo-yl)-8-nitro-2,3-di-hydro-1H-spiro-[imidazo[1,2-a]pyridine-7,3'-indolin]-2'-one including an unknown solvate.
abstract: In the title compound, C22H18BrN5O4, the central six-membered ring, derived from 1,4-di-hydro-pyridine, adopts a distorted boat conformation with a puckering amplitude of 0.197 (3) Å, the imidazole ring adopts a twisted conformation with a puckering amplitude of 0.113 (3) Å, and the oxindole moiety is planar with an r.m.s. deviation of 0.0125 Å. Two intra-molecular N-H⋯O hydrogen bonds are formed, each closing an S(6) loop. In the crystal, strong N-H⋯O hydrogen bonds lead to the formation of zigzag chains along the c axis. These are consolidated in the three-dimensional crystal packing by weak N-H⋯O hydrogen bonding, as well as by C-H⋯O, C-H⋯Br and C-H⋯π inter-actions. A small region of electron density well removed from the main mol-ecule was removed with the SQUEEZE procedure in PLATON [Spek (2009 ▶). Acta Cryst. D65, 148-155] following unsuccessful attempts to model it as a plausible solvent mol-ecule. The unit-cell characteristics do not take into account this feature of the structure.
authors.affiliation: Department of Physics, The Madura College, Madurai 625 011, India.
authors.forename: R A
authors.initials: RA
authors.lastname: Nagalakshmi
authors.affiliation: Department of Physics, The Madura College, Madurai 625 011, India.
authors.forename: J
authors.initials: J
authors.lastname: Suresh
authors.affiliation: Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai 625 021, India.
authors.forename: S
authors.initials: S
authors.lastname: Sivakumar
authors.affiliation: Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai 625 021, India.
authors.forename: R Ranjith
authors.initials: RR
authors.lastname: Kumar
authors.affiliation: Department of Food Science and Technology, University of Ruhuna, Mapalana, Kamburupitiya 81100, Sri Lanka.
authors.forename: P L Nilantha
authors.initials: PL
authors.lastname: Lakshman
keywords: crystal structure