title: Focusing neurovisceral integration: cognition, heart rate variability, and cerebral blood flow.
abstract: The neurovisceral integration hypothesis suggests in part that cerebral control of autonomic function conveys comparable control of executive function and, hence, correlation among vagally determined high frequency heart rate variability (HF-HRV), executive function, and regional cerebral blood flow (CBF). In 440 middle-aged men and women, resting HF-HRV was related to regional CBF derived from a resting arterial spin-labeled MRI scan and to seven neuropsychological tests of executive function. Despite some intercorrelations, regression modeling failed to support integrated central control of HF-HRV and executive function. Integration between autonomic and cognitive control appears more circumscribed than the general integration suggested by the neurovisceral integration hypothesis.
authors.affiliation: Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.|Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
authors.forename: J Richard
authors.initials: JR
authors.lastname: Jennings
authors.affiliation: Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.|Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
authors.forename: Ben
authors.initials: B
authors.lastname: Allen
authors.affiliation: Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.|Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Gianaros
authors.affiliation: Department of Psychology, Ohio State University, Columbus, Ohio, USA.
authors.forename: Julian F
authors.initials: JF
authors.lastname: Thayer
authors.affiliation: Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.|Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
authors.forename: Stephen B
authors.initials: SB
authors.lastname: Manuck
mesh_terms: D000328:Adult; D001341:Autonomic Nervous System / Q000502:physiology*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D003071:Cognition / Q000502:physiology*; D056344:Executive Function / Q000502:physiology; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests
keywords: Cerebral blood flow; Executive function; Heart rate variability; Neuropsychology; Neurovisceral integration