title: Unilateral choroidal granulomas complicated by choroidal neovascular membrane treated successfully with intravitreal triamcinolone in a patient with sarcoidosis.
abstract: This case describes the use of intravitreal triamcinolone in the treatment of unilateral choroidal granulomas secondary to systemic sarcoidosis complicated by choroidal neovascular membrane. A single injection of 2 mg intravitreal triamcinolone was administered as treatment for rapidly progressing choroidal granulomas and associated choroidal neovascular membrane with subretinal fluid. Visual acuity had dropped from 6/5 to 6/48 with the progressing lesions. The patient was a 52-year-old woman with type 2 diabetes mellitus who was reluctant to consider oral steroids in view of their side effect profile. Ten days after injection, visual acuity improved to 6/24 and to 6/6 at 3 months follow-up with resolution of the subretinal fluid. There was no rise in intraocular pressure. There has been no recurrence at 5 months follow-up.
authors.affiliation: James Paget University Hospital, Great Yarmouth, UK.
authors.forename: Tasneem
authors.initials: T
authors.lastname: Khatib
authors.affiliation: University of East Anglia, Norwich, UK.
authors.forename: Patrick W
authors.initials: PW
authors.lastname: Hughes
authors.affiliation: University of East Anglia, Norwich, UK James Paget University Hospital NHS Foundation Trust, Great Yarmouth, UK.
authors.forename: Benjamin J L
authors.initials: BJ
authors.lastname: Burton
mesh_terms: D002829:Choroid / Q000473:pathology*; D020256:Choroidal Neovascularization; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006099:Granuloma / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D006801:Humans; D058449:Intravitreal Injections; D008875:Middle Aged; D012507:Sarcoidosis / Q000150:complications*; D014221:Triamcinolone / Q000008:administration & dosage*; D014603:Uveal Diseases / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D014792:Visual Acuity
chemical_list: D005938:Glucocorticoids; D014221:Triamcinolone