title: Anxiety and Depression Are Better Correlates of Parkinson's Disease Quality of Life Than Apathy.
abstract: Due to controversy regarding the influence of apathy on quality of life (QoL), the authors examined the independent influence of apathy, depression, and trait anxiety in a nondemented sample of patients with Parkinson disease (PD). Participants (N=107) completed standard self-report measures of QoL and mood/motivation. Analyses investigated the contribution of these measures and empirically derived factor scores on QoL. QoL was predicted by trait anxiety, dysphoria, and decreased interest, with no independent contribution of apathy. Different patterns emerged with respect to domain-specific QoL, with trait anxiety being the strongest predictor across most domains. Anxiety was most widely related to QoL in PD, with minimal contribution of apathy. Future studies should examine different roles of PD mood/motivation symptoms on caregiver QoL.
authors.affiliation: From the Dept. of Clinical and Health Psychology (JDJ, LCB, JL, PM, DB), Dept. of Neurology (MSO, DB), and Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville, FL; and Dept. of Psychiatry, University of Michigan, Ann Arbor, MI (WS).
authors.forename: Jacob D
authors.initials: JD
authors.lastname: Jones
authors.affiliation: From the Dept. of Clinical and Health Psychology (JDJ, LCB, JL, PM, DB), Dept. of Neurology (MSO, DB), and Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville, FL; and Dept. of Psychiatry, University of Michigan, Ann Arbor, MI (WS).
authors.forename: London C
authors.initials: LC
authors.lastname: Butterfield
authors.affiliation: From the Dept. of Clinical and Health Psychology (JDJ, LCB, JL, PM, DB), Dept. of Neurology (MSO, DB), and Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville, FL; and Dept. of Psychiatry, University of Michigan, Ann Arbor, MI (WS).
authors.forename: Woojin
authors.initials: W
authors.lastname: Song
authors.affiliation: From the Dept. of Clinical and Health Psychology (JDJ, LCB, JL, PM, DB), Dept. of Neurology (MSO, DB), and Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville, FL; and Dept. of Psychiatry, University of Michigan, Ann Arbor, MI (WS).
authors.forename: Jacob
authors.initials: J
authors.lastname: Lafo
authors.affiliation: From the Dept. of Clinical and Health Psychology (JDJ, LCB, JL, PM, DB), Dept. of Neurology (MSO, DB), and Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville, FL; and Dept. of Psychiatry, University of Michigan, Ann Arbor, MI (WS).
authors.forename: Paul
authors.initials: P
authors.lastname: Mangal
authors.affiliation: From the Dept. of Clinical and Health Psychology (JDJ, LCB, JL, PM, DB), Dept. of Neurology (MSO, DB), and Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville, FL; and Dept. of Psychiatry, University of Michigan, Ann Arbor, MI (WS).
authors.forename: Michael S
authors.initials: MS
authors.lastname: Okun
authors.affiliation: From the Dept. of Clinical and Health Psychology (JDJ, LCB, JL, PM, DB), Dept. of Neurology (MSO, DB), and Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville, FL; and Dept. of Psychiatry, University of Michigan, Ann Arbor, MI (WS).
authors.forename: Dawn
authors.initials: D
authors.lastname: Bowers
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001007:Anxiety / Q000209:etiology*; D057565:Apathy; D003863:Depression / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000523:psychology*; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life / Q000523:psychology*; D057566:Self Report; D013223:Statistics as Topic; D011795:Surveys and Questionnaires