title: Dinuclear [{(p-cym)RuCl}2(μ-phpy)](PF6)2 and heterodinuclear [(ppy)2Ir(μ-phpy)Ru(p-cym)Cl](PF6)2 complexes: synthesis, structure and anticancer activity.
abstract: Phpy bridged homodinuclear Ru-Ru () and heterodinuclear Ir-Ru complexes () have been developed. Complex induces autophagy towards the cisplatin resistant human breast cancer (MCF7) cell line, whereas is inactive.
authors.affiliation: School of Basic Sciences, Indian Institute of Technology Bhubaneswar, Bhubaneswar-751007, India. srikanta@iitbbs.ac.in.
authors.forename: Suman Kumar
authors.initials: SK
authors.lastname: Tripathy
authors.forename: Umasankar
authors.initials: U
authors.lastname: De
authors.forename: Niranjan
authors.initials: N
authors.lastname: Dehury
authors.forename: Satyanarayan
authors.initials: S
authors.lastname: Pal
authors.forename: Hyung Sik
authors.initials: HS
authors.lastname: Kim
authors.forename: Srikanta
authors.initials: S
authors.lastname: Patra
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D001343:Autophagy / Q000187:drug effects*; D045744:Cell Line, Tumor; D002945:Cisplatin / Q000737:chemistry / Q000494:pharmacology; D056831:Coordination Complexes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D019008:Drug Resistance, Neoplasm / Q000187:drug effects*; D006801:Humans; D015394:Molecular Structure; D061848:Optical Imaging; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D000970:Antineoplastic Agents; D056831:Coordination Complexes; D012428:Ruthenium; D002945:Cisplatin