title: 99mTc-HMPAO-labeled WBC scan for the diagnosis of chronic recurrent multifocal osteomyelitis.
abstract: The goal of this teaching case study is to demonstrate the novel use of (99m)Tc-HMPAO-labeled white blood cells (WBCs) in diagnosing chronic recurrent multifocal osteomyelitis (CRMO). (99m)Tc-HMPAO-labeled white blood cells were utilized to diagnose CRMO. Classically, CRMO is evaluated scintigraphically using (99m)Tc-methylene diphosphonate/hydroxymethylene diphosphonate. (99m)Tc-HMPAO-labeled WBCs were chosen over (111)In-labeled WBCs because of the former's improved imaging characteristics and decreased radiation dose. (99m)Tc-HMPAO-labeled WBCs were successful in diagnosing CRMO. (99m)Tc-HMPAO-labeled WBC scanning is specific for the diagnosis of CRMO.
authors.affiliation: Department of Radiology, San Antonio Military Medical Center, Fort Sam Houston, Texas tyler.a.dailey2.mil@mail.mil.
authors.forename: Tyler A
authors.initials: TA
authors.lastname: Dailey
authors.affiliation: Department of Radiology, San Antonio Military Medical Center, Fort Sam Houston, Texas.
authors.forename: Michael D
authors.initials: MD
authors.lastname: Berven
authors.affiliation: Department of Radiology, San Antonio Military Medical Center, Fort Sam Houston, Texas.
authors.forename: Penny J
authors.initials: PJ
authors.lastname: Vroman
mesh_terms: D002648:Child; D006801:Humans; D007962:Leukocytes; D008279:Magnetic Resonance Imaging; D008297:Male; D010019:Osteomyelitis / Q000175:diagnosis*; D019690:Technetium Tc 99m Exametazime
chemical_list: D019690:Technetium Tc 99m Exametazime
keywords: HMPAO; bone scan; chronic recurrent multifocal osteomyelitis; pediatric