title: Hemodynamic indexes derived from computed tomography angiography to predict pulmonary embolism related mortality.
abstract: Pulmonary embolism (PE) induces an acute increase in the right ventricle afterload that can lead to right-ventricular dysfunction (RVD) and eventually to circulatory collapse. Hemodynamic status and presence of RVD are important determinants of adverse outcomes in acute PE. Technologic progress allows computed tomography angiography (CTA) to give more information than accurate diagnosis of PE. It may also provide an insight into hemodynamics and right-ventricular function. Proximal localization of emboli, reflux of contrast medium to the hepatic veins, and right-to-left short-axis ventricular diameter ratio seem to be the most relevant CTA predictors of 30-day mortality. These elements require little postprocessing time, an advantage in the emergency room. We herein review the prognostic value of RVD and other CTA mortality predictors for patients with acute PE.
authors.affiliation: Department of Internal Medicine, Rehabilitation and Geriatrics, Geneva University Hospitals (HUG), Gabrielle-Perret-Gentil 4, 1205 Geneva, Switzerland.
authors.forename: Gregor
authors.initials: G
authors.lastname: John
authors.affiliation: Department of Internal Medicine, Rehabilitation and Geriatrics, Geneva University Hospitals (HUG), Gabrielle-Perret-Gentil 4, 1205 Geneva, Switzerland.
authors.forename: Christophe
authors.initials: C
authors.lastname: Marti
authors.affiliation: Department of Radiology, Emergency-Room Radiology Unit, Geneva University Hospitals (HUG), Gabrielle-Perret-Gentil 4, 1205 Geneva, Switzerland.
authors.forename: Pierre-Alexandre
authors.initials: PA
authors.lastname: Poletti
authors.affiliation: Department of Internal Medicine, Rehabilitation and Geriatrics, Geneva University Hospitals (HUG) and Geneva Faculty of Medicine, Gabrielle-Perret-Gentil 4, 1211 Geneva, Switzerland.
authors.forename: Arnaud
authors.initials: A
authors.lastname: Perrier
mesh_terms: D000792:Angiography / Q000379:methods; D006352:Heart Ventricles / Q000503:physiopathology; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D011379:Prognosis; D011655:Pulmonary Embolism / Q000150:complications* / Q000503:physiopathology*; D014057:Tomography, X-Ray Computed / Q000379:methods; D018497:Ventricular Dysfunction, Right / Q000503:physiopathology