title: Enhanced ratiometric fluorescent indicators for magnesium based on azoles of the heavier chalcogens.
abstract: Red-shifted fluorescent indicators for magnesium were developed by incorporation of sulfur or selenium in the azole moiety of 'fura' fluorophores. Single atom replacement in the acceptor of these ITC probes affords longer excitation and emission wavelengths as well as greater separation between excitation bands, valuable for ratiometric intracellular Mg(2+) imaging.
authors.affiliation: Department of Chemistry, New York University, New York, NY 10003, USA. dbuccella@nyu.edu.
authors.forename: Mohammad S
authors.initials: MS
authors.lastname: Afzal
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Pitteloud
authors.forename: Daniela
authors.initials: D
authors.lastname: Buccella
mesh_terms: D001393:Azoles / Q000737:chemistry*; D018011:Chalcogens / Q000737:chemistry*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D017616:Magnesium Compounds / Q000737:chemistry*; D012643:Selenium / Q000737:chemistry; D013455:Sulfur / Q000737:chemistry
chemical_list: D001393:Azoles; D018011:Chalcogens; D005456:Fluorescent Dyes; D017616:Magnesium Compounds; D013455:Sulfur; D012643:Selenium