title: Antimicrobial and toxicological studies of Ochthochloa compressa plant.
abstract: The present study demonstrates the biological activity of Ochthochloa compressa, since extensive literature survey has shown no documented biological activity of this plant. Ethanolic extract of whole plant was prepared and evaporated under reduced pressure by rota vapor. The crude extract was further fractionated into n-hexane, dichloromethane, ethyl acetate and n-butanol soluble fractions. These fractions were screened for antifungal, phytotoxic, cytotoxic and antibacterial activities. Dichloromethane soluble fraction showed significant phytotoxicity whereas n-hexane, ethyl acetate, and n-butanol soluble fractions showed non-significant phytotoxicity. Similarly, ethyl acetate soluble fraction was the only fraction, which showed significant cytotoxic activity. There was no antibacterial but moderate antifungal activity was shown by these fractions against selected strains of bacteria and fungi. This is the first report on the biological activity of O. compressa.
authors.affiliation: Faculty of Pharmacy & Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
authors.forename: Saeed
authors.initials: S
authors.lastname: Ahmad
authors.affiliation: Faculty of Pharmacy & Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
authors.forename: Muhammad Tayyab
authors.initials: MT
authors.lastname: Bashir
authors.affiliation: Faculty of Pharmacy & Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
authors.forename: Farhan Hameed
authors.initials: FH
authors.lastname: Khaliq
authors.affiliation: Faculty of Pharmacy & Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
authors.forename: Abdul
authors.initials: A
authors.lastname: Mannan
authors.affiliation: Faculty of Pharmacy & Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
authors.forename: Muhammad Fahad
authors.initials: MF
authors.lastname: Mukhtar
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology*; D006109:Poaceae
chemical_list: D000890:Anti-Infective Agents; D010936:Plant Extracts