title: Damage threshold from large retinal spot size repetitive-pulse laser exposures.
abstract: The retinal damage thresholds for large spot size, multiple-pulse exposures to a Q-switched, frequency doubled Nd:YAG laser (532 nm wavelength, 7 ns pulses) have been measured for 100 μm and 500 μm retinal irradiance diameters. The ED50, expressed as energy per pulse, varies only weakly with the number of pulses, n, for these extended spot sizes. The previously reported threshold for a multiple-pulse exposure for a 900 μm retinal spot size also shows the same weak dependence on the number of pulses. The multiple-pulse ED50 for an extended spot-size exposure does not follow the n dependence exhibited by small spot size exposures produced by a collimated beam. Curves derived by using probability-summation models provide a better fit to the data.
authors.affiliation: *U.S. Army Institute of Surgical Research, 3698 Chambers Pass, JBSA Fort Sam Houston, TX 78234-6315.
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Lund
authors.forename: David J
authors.initials: DJ
authors.lastname: Lund
authors.forename: Peter R
authors.initials: PR
authors.lastname: Edsall
mesh_terms: D000818:Animals; D004307:Dose-Response Relationship, Radiation; D005131:Eye Injuries / Q000209:etiology; D007834:Lasers / Q000009:adverse effects*; D008253:Macaca mulatta; D011336:Probability; D011829:Radiation Dosage; D012160:Retina / Q000528:radiation effects*