title: Mucinous tubular and spindle cell carcinoma of the kidney: the contrast-enhanced ultrasonography and CT features of six cases and review of the literature.
abstract: OBJECTIVE
  To report the features of contrast-enhanced ultrasonography (CEUS) and computer tomography (CECT) of mucinous tubular and spindle cell carcinoma (MTSCC) of the kidney.
  
  
  METHODS
  Six cases of MTSCC of the kidney were studied, and the literature was reviewed. Ultrasonography, CEUS, and CECT examinations were routinely performed before the operation. Histological analysis, including HE staining and immunohistochemistry, was performed with the envision method.
  
  
  RESULTS
  The age of the patients ranged from 48 to 75 years (mean 55.5 years). One patient was male, and five were females. All six tumours exhibited an admixture of tubules, spindle cells, and mucinous stroma in variable proportions. CEUS and CECT showed enhancement of the lesions, but the enhancement was less than the adjacent renal parenchyma, leading to the diagnosis of hypovascular renal tumours. All patients were alive and well at the follow-up time of 17-73 months (mean 39.5 months) with CEUS and/or CECT at 3 months, 6 months, and 1 year and then annually thereafter following surgery. No metastases were detected.
  
  
  CONCLUSIONS
  The CEUS and CECT findings of MTSCC were generally hypovascular and needed to be distinguished from other hypovascular renal tumours.
authors.affiliation: Department of Urology, The Affiliated Nanjing Drum Tower Hospital, Nanjing University Medical School, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Shiwei
authors.initials: S
authors.lastname: Zhang
authors.forename: Xiaozhi
authors.initials: X
authors.lastname: Zhao
authors.forename: Shun
authors.initials: S
authors.lastname: Zhang
authors.forename: Guangxiang
authors.initials: G
authors.lastname: Liu
authors.forename: Hongqian
authors.initials: H
authors.lastname: Guo
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000000981:diagnostic imaging* / Q000601:surgery; D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000601:surgery; D003287:Contrast Media; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007472:Iohexol; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery; D007684:Kidney Tubules / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D010743:Phospholipids; D013459:Sulfur Hexafluoride; D014057:Tomography, X-Ray Computed; D018615:Ultrasonography, Doppler, Color
chemical_list: D003287:Contrast Media; D010743:Phospholipids; C420843:contrast agent BR1; D007472:Iohexol; D013459:Sulfur Hexafluoride