title: Human immunodeficiency virus and coinfection with hepatitis B and C.
abstract: In HIV-infected individuals, coinfection with HBV and/or HCV is common because of shared modes of transmission. It is known that HIV accelerates progression of liver disease and results in increased morbidity and mortality associated with viral hepatitis, but it is less clear if viral hepatitis has a direct effect on HIV. Treatment of viral hepatitis improves outcomes and should be considered in all HIV-infected patients. Treatment of HBV without concurrent treatment of HIV is risky because resistance can occur in both viruses if regimens are not carefully chosen.
authors.affiliation: Department of Infectious Diseases and Global Health, University of Chicago Medical Center, 5841 South Maryland Avenue, MC 5065, Chicago, IL 60637, USA. Electronic address: lindsay.petty@uchospitals.edu.
authors.forename: Lindsay A
authors.initials: LA
authors.lastname: Petty
authors.affiliation: Department of Infectious Diseases and Global Health, University of Chicago Medical Center, 5841 South Maryland Avenue, MC 5065, Chicago, IL 60637, USA.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Steinbeck
authors.affiliation: Department of Infectious Diseases and Global Health, University of Chicago Medical Center, 5841 South Maryland Avenue, MC 5065, Chicago, IL 60637, USA.
authors.forename: Kenneth
authors.initials: K
authors.lastname: Pursell
authors.affiliation: Department of Medicine, Center for Liver Disease, University of Chicago Medical Center, 5841 South Maryland Avenue, MC 7120, Chicago, IL 60637, USA.
authors.forename: Donald M
authors.initials: DM
authors.lastname: Jensen
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D060085:Coinfection / Q000188:drug therapy / Q000453:epidemiology* / Q000473:pathology; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy / Q000401:mortality / Q000473:pathology; D019694:Hepatitis B, Chronic / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology; D019698:Hepatitis C, Chronic / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology; D006801:Humans
chemical_list: D000998:Antiviral Agents
keywords: Coinfection; DAA; HIV; Hepatitis B virus; Hepatitis C virus