title: Atrial Fibrillation Is Associated With Increased Mean Platelet Volume and Apnea Hypopnea Index in Patients With Obstructive Sleep Apnea.
abstract: This study investigated whether there is a relationship between atrial fibrillation (AF), mean platelet volume (MPV), and apnea hypopnea index (AHI) in patients who have obstructive sleep apnea syndrome (OSAS). We enrolled patients who had OSAS with either AF or normal sinus rhythm (NSR). We divided 90 patients (aged 50-80 years) into 2 groups: group 1 consisted of 40 patients with OSAS having AF and group 2 of 50 patients with OSAS having NSR. Mean platelet volume was higher in patients with AF than in those with NSR (9.8 ± 0.6 vs 8.4 ± 0.6 fL; P < .001). The MPV and AHI were substantial variables associated with AF (odds ratio [OR] = 2.41; 95% confidence interval [CI], 1.36-5.26; P < .004 and OR = 1.91; 95% CI, 1.26-3.32; P = .02). Elevated MPV value of ≥9.4 fL is associated with AF (70% sensitivity and 63% specificity). More research is needed to establish the clinical relevance of this association.
authors.affiliation: Department of Cardiology, Faculty of Medicine, Namık Kemal University, Tekirdağ, Turkey ayakyuzq5@gmail.com.
authors.forename: Aydın
authors.initials: A
authors.lastname: Akyüz
authors.affiliation: Department of Cardiology, Faculty of Medicine, Namık Kemal University, Tekirdağ, Turkey.
authors.forename: Dursun Çayan
authors.initials: DÇ
authors.lastname: Akkoyun
authors.affiliation: Department of Cardiology, Faculty of Medicine, Namık Kemal University, Tekirdağ, Turkey.
authors.forename: Hasan
authors.initials: H
authors.lastname: Değirmenci
authors.affiliation: Department of Neurology, Faculty of Medicine, Namık Kemal University, Tekirdağ, Turkey.
authors.forename: Recep
authors.initials: R
authors.lastname: Alp
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019540:Area Under Curve; D001281:Atrial Fibrillation / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D063847:Mean Platelet Volume; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D015539:Platelet Activation; D011237:Predictive Value of Tests; D011379:Prognosis; D012372:ROC Curve; D012189:Retrospective Studies; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000097:blood / Q000150:complications* / Q000175:diagnosis
keywords: atrial fibrillation; mean platelet volume; obstructive sleep apnea syndrome