title: [First trimester miscarriages: benefits and harms of different management options].
abstract: The objective of this review was to assess early and late benefits and harms of different management options for first-trimester miscarriage. Surgical uterine evacuation remains the most effective and the quickest method of treatment. Depending on the clinical situation, medical treatment using misoprostol (missed miscarriage) or expectative attitude (incomplete miscarriage) does not increase the risk of complications, neither haemorrhagic nor infectious. However, these alternatives generally require longer outpatient follow-up, which leads to more prolonged bleeding and not planned surgical procedures.
authors.affiliation: Service de gynécologie obstétrique et médecine de la reproduction, CHU de Caen, avenue Côte-de-Nacre, 14033 Caen cedex 9, France. Electronic address: beucher-g@chu-caen.fr.
authors.forename: G
authors.initials: G
authors.lastname: Beucher
authors.affiliation: Service de gynécologie obstétrique et médecine de la reproduction, CHU de Caen, avenue Côte-de-Nacre, 14033 Caen cedex 9, France.
authors.forename: P
authors.initials: P
authors.lastname: Dolley
authors.affiliation: Service de gynécologie obstétrique et médecine de la reproduction, CHU de Caen, avenue Côte-de-Nacre, 14033 Caen cedex 9, France; UFR de médecine, université de Caen Basse Normandie, avenue Côte-de-Nacre, 14033 Caen cedex 9, France.
authors.forename: Z
authors.initials: Z
authors.lastname: Stewart
authors.affiliation: Service de gynécologie obstétrique, centre hospitalier de l'Ouest Guyanais, 16, avenue du Général-de-Gaulle, BP 245, 97393 Saint-Laurent-du-Maroni cedex, Guyane française.
authors.forename: G
authors.initials: G
authors.lastname: Carles
authors.affiliation: Service de gynécologie obstétrique et médecine de la reproduction, CHU de Caen, avenue Côte-de-Nacre, 14033 Caen cedex 9, France; UFR de médecine, université de Caen Basse Normandie, avenue Côte-de-Nacre, 14033 Caen cedex 9, France. Electronic address: dreyfus-m@chu-caen.fr.
authors.forename: M
authors.initials: M
authors.lastname: Dreyfus
mesh_terms: D000022:Abortion, Spontaneous / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D005260:Female; D006801:Humans; D016595:Misoprostol / Q000627:therapeutic use; D013513:Obstetric Surgical Procedures; D011247:Pregnancy; D011261:Pregnancy Trimester, First
chemical_list: D016595:Misoprostol
keywords: Aspiration utérine chirurgicale; Chirurgical uterine evacuation; Early pregnancy failure; Fausse couche du premier trimestre; First-trimester miscarriage; Misoprostol; Échec précoce de grossesse