title: A comprehensive study of sampling-based optimum signal detection in concentration-encoded molecular communication.
abstract: In this paper, a comprehensive analysis of the sampling-based optimum signal detection in ideal (i.e., free) diffusion-based concentration-encoded molecular communication (CEMC) system has been presented. A generalized amplitude-shift keying (ASK)-based CEMC system has been considered in diffusion-based noise and intersymbol interference (ISI) conditions. Information is encoded by modulating the amplitude of the transmission rate of information molecules at the TN. The critical issues involved in the sampling-based receiver thus developed are addressed in detail, and its performance in terms of the number of samples per symbol, communication range, and transmission data rate is evaluated. ISI produced by the residual molecules deteriorates the performance of the CEMC system significantly, which further deteriorates when the communication range and/or the transmission data rate increase(s). In addition, the performance of the optimum receiver depends on the receiver's ability to compute the ISI accurately, thus providing a trade-off between receiver complexity and achievable bit error rate (BER). Exact and approximate detection performances have been derived. Finally, it is found that the sampling-based signal detection scheme thus developed can be applied to both binary and multilevel (M-ary) ASK-based CEMC systems, although M-ary systems suffer more from higher BER.
authors.forename: Mohammad U
authors.initials: MU
authors.lastname: Mahfuz
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Makrakis
authors.forename: Hussein T
authors.initials: HT
authors.lastname: Mouftah
mesh_terms: D001709:Biotechnology; D003142:Communication; D003198:Computer Simulation; D039301:Computers, Molecular; D008962:Models, Theoretical; D036103:Nanotechnology; D012815:Signal Processing, Computer-Assisted