title: Age-dependent hepatocyte transplantation for functional liver tissue reconstitution.
abstract: The transplantation of hepatocytes could be an alternative therapeutic option to the whole organ transplantation for the treatment of end-stage liver diseases. However, this cell-based therapy needs the understanding of the molecular mechanisms to improve efficacy. This chapter includes a detailed method of a rat model for liver regeneration studies after age-dependent hepatocyte transplantation.
authors.affiliation: Department of Surgery, University of Leipzig, Liebigstraße 21, 04103, Leipzig, Germany, peggy.stock@medizin.uni-leipzig.de.
authors.forename: Peggy
authors.initials: P
authors.lastname: Stock
mesh_terms: D000367:Age Factors; D000818:Animals; D064987:Cell- and Tissue-Based Therapy; D022781:Hepatocytes / Q000637:transplantation*; D007150:Immunohistochemistry; D008099:Liver / Q000166:cytology / Q000378:metabolism / Q000601:surgery; D008115:Liver Regeneration; D051381:Rats; D019172:Transplantation Conditioning