title: Aldehyde-assisted ruthenium(II)-catalyzed C-H oxygenations.
abstract: Versatile ruthenium(II) complexes allow for site-selective C-H oxygenations with weakly-coordinating aldehydes. The challenging C-H functionalizations proceed with high chemoselectivity by rate-determining C-H metalation. The new method features an ample substrate scope, which sets the stage for the step-economical preparation of various bioactive heterocycles.
authors.affiliation: Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstraße 2, 37077 Göttingen (Germany) http://www.ackermann.chemie.uni-goettingen.de/
authors.forename: Fanzhi
authors.initials: F
authors.lastname: Yang
authors.forename: Karsten
authors.initials: K
authors.lastname: Rauch
authors.forename: Katharina
authors.initials: K
authors.lastname: Kettelhoit
authors.forename: Lutz
authors.initials: L
authors.lastname: Ackermann
keywords: CH activation; aldehydes; chemoselectivity; oxygenation; ruthenium