title: Hepatitis B core antibody-positive donors in cardiac transplantation: a single-center experience.
abstract: Hepatitis B virus (HBV) core antibody (HBcAb)-positive donors are increasingly utilized in solid organ transplantation. We report a single center's experience in cardiac transplantation with 18 HBcAb-positive donors. Available follow-up on recipients of cardiac allografts from HBcAb-positive donors, including 2 donors with low-level serum HBV DNA at the time of transplantation, demonstrated no documented donor-derived HBV transmission.
authors.affiliation: Department of Medicine/Infectious Diseases, Duke University Medical Center, Durham, North Carolina, USA.
authors.forename: J L
authors.initials: JL
authors.lastname: Horan
authors.forename: J E
authors.initials: JE
authors.lastname: Stout
authors.forename: B D
authors.initials: BD
authors.lastname: Alexander
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004279:DNA, Viral / Q000097:blood*; D046148:Donor Selection; D005260:Female; D005500:Follow-Up Studies; D016027:Heart Transplantation; D006509:Hepatitis B / Q000635:transmission*; D006510:Hepatitis B Antibodies / Q000097:blood*; D006512:Hepatitis B Core Antigens / Q000276:immunology*; D006514:Hepatitis B Surface Antigens / Q000276:immunology; D006515:Hepatitis B virus / Q000235:genetics / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015996:Survival Rate; D055815:Young Adult
chemical_list: D004279:DNA, Viral; D006510:Hepatitis B Antibodies; D006512:Hepatitis B Core Antigens; D006514:Hepatitis B Surface Antigens
keywords: cardiac transplantation; donor-derived infections; hepatitis B virus