title: A seroepidemiological Study of Hepatitis B and C Virus (HBV and HCV) Infections in the Young Population in parts of Busan, Korea.
abstract: OBJECTIVE
  To investigate the prevalence of hepatitis B and C virus infections and determine the associated risk factors among young adults in Busan, Korea, which is known to have a high incidence of liver cancer.
  
  
  METHODS
  The study population consisted of volunteer participants in a health survey during 2002, which included 1, 350 students (515 males and 835 females) aged between 16 and 24 years, from three different schools in Busan. The participating students were asked to fill in a selfadministered questionnaire which included lifestyle habits and risk factors of hepatitis. Sera obtained from the participants were studied for HBsAg, anti-HBs, and Anti- HCV by enzyme immunoassay (EIA) method and for liver function tests.
  
  
  RESULTS
  Among the study subjects (N=1, 350), the seropositivities of HBsAg 7.9% (95% CI=7.8-8.0), 7.6% (95% CI=7.6-7.7) in male and 8.1% (95% CI=8.0-8.2) in female. And the seropositivity of Anti-HBs was 69.7% (95% CI=69.0- 70.4), 70.5% (95% CI=69.8-71.2) in male and 69.2% (95% CI=68.5-69.9) in female. The seropositivity of Anti-HCV was 0.4%, 0.2% in male and 0.5% in female. The seropositivity for HBsAg in the subjects not having a hepatitis B vaccination history was twice (95% CI=1.0-4.4) that of those that did. Also, the seropositivity for HBsAg in subjects having experienced sexual intercourse was 1.7 times (95% CI=0.9-3.0) that of the subjects who had not.
  
  
  CONCLUSIONS
  The present study confirmed the high prevalence of HBsAg seropositivity and sexual transmission of HBV among adolescents and young adults may occur. Further studies to evaluate the relationship between HBV vaccination and sexual transmission are required for the young population in Korea.
authors.affiliation: Division of Cancer Control & Epidemiology, Research Institute, National Cancer Center, Korea. hrshin@ncc.re.kr.
authors.forename: Young Hee
authors.initials: YH
authors.lastname: Ju
authors.affiliation: Division of Cancer Control & Epidemiology, Research Institute, National Cancer Center, Korea. hrshin@ncc.re.kr.
authors.forename: Hai Rim
authors.initials: HR
authors.lastname: Shin
authors.affiliation: Division of Cancer Control & Epidemiology, Research Institute, National Cancer Center, Korea. hrshin@ncc.re.kr.
authors.forename: Jin Kyoung
authors.initials: JK
authors.lastname: Oh
authors.affiliation: Division of Cancer Control & Epidemiology, Research Institute, National Cancer Center, Korea. hrshin@ncc.re.kr.
authors.forename: Dong Il
authors.initials: DI
authors.lastname: Kim
authors.affiliation: Division of Cancer Control & Epidemiology, Research Institute, National Cancer Center, Korea. hrshin@ncc.re.kr.
authors.forename: Duk Hee
authors.initials: DH
authors.lastname: Lee
authors.affiliation: Division of Cancer Control & Epidemiology, Research Institute, National Cancer Center, Korea. hrshin@ncc.re.kr.
authors.forename: Byeong Kweon
authors.initials: BK
authors.lastname: Kim
authors.affiliation: Division of Cancer Control & Epidemiology, Research Institute, National Cancer Center, Korea. hrshin@ncc.re.kr.
authors.forename: Jung Il
authors.initials: JI
authors.lastname: Kim
authors.affiliation: Division of Cancer Control & Epidemiology, Research Institute, National Cancer Center, Korea. hrshin@ncc.re.kr.
authors.forename: Kap Yeol
authors.initials: KY
authors.lastname: Jung
keywords: Hepatitis B virus; Hepatitis C virus; Korea; Transmission