title: Correlation between corpus callosum sub-segmental area and cognitive processes in school-age children.
abstract: We assessed the relationship between structural characteristics (area) and microstructure (apparent diffusion coefficient; ADC) of the corpus callosum (CC) in 57 healthy children aged 7.0 to 9.1 years, with diverse cognitive and academic abilities as well as executive functions evaluated with a neuropsychological battery for children. The CC was manually delineated and sub-segmented into six regions, and their ADC and area were measured. There were no significant differences between genders in the callosal region area or in ADC. The CC area and ADC, mainly of anterior regions, correlated with different cognitive abilities for each gender. Our results suggest that the relationship between cognitive abilities and CC characteristics is different between girls and boys and between the anterior and posterior regions of the CC. Furthermore, these findings strenghten the idea that regardless of the different interhemispheric connectivity schemes per gender, the results of cognitive tasks are very similar for girls and boys throughout childhood.
authors.affiliation: Universidad Nacional Autónoma de México, Instituto de Neurobiología, Querétaro, México.
authors.forename: Martha Beatriz
authors.initials: MB
authors.lastname: Moreno
authors.affiliation: Universidad Nacional Autónoma de México, Instituto de Neurobiología, Querétaro, México.
authors.forename: Luis
authors.initials: L
authors.lastname: Concha
authors.affiliation: Universidad Nacional Autónoma de México, Instituto de Neurobiología, Querétaro, México.
authors.forename: Leopoldo
authors.initials: L
authors.lastname: González-Santos
authors.affiliation: Universidad Nacional Autónoma de México, Instituto de Neurobiología, Querétaro, México.
authors.forename: Juan Jose
authors.initials: JJ
authors.lastname: Ortiz
authors.affiliation: Universidad Nacional Autónoma de México, Instituto de Neurobiología, Querétaro, México.
authors.forename: Fernando Alejandro
authors.initials: FA
authors.lastname: Barrios
mesh_terms: D002648:Child; D002657:Child Development; D003071:Cognition; D003337:Corpus Callosum / Q000033:anatomy & histology* / Q000502:physiology*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D008297:Male; D012727:Sex Characteristics