title: [Relationship between high normal blood pressure and carotid artery atherosclerosis in Beijing residents].
abstract: OBJECTIVE
  To analyze the relationship between normal high blood pressure and carotid artery atherosclerosis.
  
  
  METHODS
  This epidemiological survey was performed in two communities of Shijingshan District of Beijing from 2007 to 2008. A total of 3 324 people were enrolled in the study and 2 895 people with carotid ultrasound survey results were analyzed. Blood lipids, blood pressure, hs-CRP, body mass index (BMI) and other cardiovascular risk factors were obtained. Carotid mean intima-media thickness (IMT) , maximum carotid IMT and carotid plaque were measured by ultrasound. A multiple logistic regression model was used to evaluate the relationship between normal high blood pressure and carotid artery atherosclerosis.
  
  
  RESULTS
  The carotid mean IMT, maximum IMT, incidence of carotid artery plaque increased in proportion to blood pressure level (all P < 0.01) . After adjusting for diabetes, hypercholesterolemia, hypertriglyceridemia, increased hs-CRP, smoking, sex, age, overweight and obesity, multiple logistic regression analysis showed that the OR values of carotid mean IMT and maximum IMT thickening, carotid plaque in high normal blood pressure group were 4.50 (95% CI: 1.04-19.49, P < 0.05), 1.73 (95% CI: 1.35-2.22, P < 0.01), 1.64 (95% CI:1.26-2.13, P < 0.01) compared to normal blood pressure group.
  
  
  CONCLUSIONS
  High normal blood pressure is related with higher risk of carotid artery atherosclerosis in this cohort.
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Ma
authors.forename: Ying
authors.initials: Y
authors.lastname: Yang
authors.forename: Litong
authors.initials: L
authors.lastname: Qi
authors.forename: Baowei
authors.initials: B
authors.lastname: Zhang
authors.forename: Lei
authors.initials: L
authors.lastname: Meng
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Jie
authors.initials: J
authors.lastname: Jiang
authors.forename: Jianping
authors.initials: J
authors.lastname: Li
authors.forename: Shuyu
authors.initials: S
authors.lastname: Wang
authors.affiliation: Email: huoyong@263.net.cn.
authors.forename: Yong
authors.initials: Y
authors.lastname: Huo
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure; D002340:Carotid Artery Diseases / Q000453:epidemiology* / Q000473:pathology; D059168:Carotid Intima-Media Thickness; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012307:Risk Factors