title: [Main factors of remodeling of vascular wall].
abstract: With a purpose of identifying and ranking factors influencing remodeling of vascular wall in 168 practically healthy subjects (71 men, 97 women) aged 30-60 years we conducted a study of risk factors of cardiovascular disease, and infectious, immunological, inflammatory and metabolic parameters. Using artificial neural network we found that process of remodeling of vascular wall was most significantly impacted by: cytomegalovirus and hlamydia neumoniae infections, decreased number of T-lymphocytes, development of latent vascular microinflammation, and diastolic blood pressure above 80 mm Hg.
authors.forename: A P
authors.initials: AP
authors.lastname: Shavrin
authors.forename: Ia B
authors.initials: IaB
authors.lastname: Khovaeva
authors.forename: B V
authors.initials: BV
authors.lastname: Golovskoĭ
authors.forename: M D
authors.initials: MD
authors.lastname: Berg
mesh_terms: D000328:Adult; D001794:Blood Pressure; D001808:Blood Vessels / Q000276:immunology / Q000473:pathology / Q000503:physiopathology; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000209:etiology / Q000276:immunology / Q000503:physiopathology; D061387:Chlamydial Pneumonia / Q000150:complications / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000150:complications / Q000276:immunology; D005260:Female; D006801:Humans; D007249:Inflammation / Q000276:immunology / Q000503:physiopathology; D018655:Lymphocyte Count; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013223:Statistics as Topic; D013601:T-Lymphocytes / Q000276:immunology*