title: Late-stage diversification of peptides by metal-free C-H arylation.
abstract: The bioorthogonal late-stage diversification of functionalized oligopeptides was accomplished through a metal-free, site-selective C-H arylation of engineered indole derivatives under mild reaction conditions.
authors.affiliation: Institut für Organische und Biomolekulare Chemie, Georg-August-Universität, Tammannstrasse 2, 37077 Göttingen (Germany), Fax: (+49) 551-39-6777.
authors.forename: Yingjun
authors.initials: Y
authors.lastname: Zhu
authors.forename: Michaela
authors.initials: M
authors.lastname: Bauer
authors.forename: Jasper
authors.initials: J
authors.lastname: Ploog
authors.forename: Lutz
authors.initials: L
authors.lastname: Ackermann
mesh_terms: D002244:Carbon / Q000737:chemistry; D006859:Hydrogen / Q000737:chemistry; D007210:Indoleacetic Acids / Q000737:chemistry; D008670:Metals / Q000737:chemistry; D010455:Peptides / Q000737:chemistry*
chemical_list: D007210:Indoleacetic Acids; D008670:Metals; D010455:Peptides; D002244:Carbon; D006859:Hydrogen; C015950:indoleacetamide
keywords: CH activation; chemoselective reactions; late stage diversification; metal-free reactions; peptides