title: A coinfection model for HIV and HCV.
abstract: We study a mathematical model for the human immunodeficiency virus (HIV) and hepatites C virus (HCV) coinfection. The model predicts four distinct equilibria: the disease free, the HIV endemic, the HCV endemic, and the full endemic equilibria. The local and global stability of the disease free equilibrium was calculated for the full model and the HIV and HCV submodels. We present numerical simulations of the full model where the distinct equilibria can be observed. We show simulations of the qualitative changes of the dynamical behavior of the full model for variation of relevant parameters. From the results of the model, we infer possible measures that could be implemented in order to reduce the number of infected individuals.
authors.affiliation: Faculty of Sciences, University of Porto, Rua do Campo Alegre s/n, 4440-452 Porto, Portugal. Electronic address: up200802541@fc.up.pt.
authors.forename: Ana R M
authors.initials: AR
authors.lastname: Carvalho
authors.affiliation: School of Engineering, Polytechnic of Porto, and Centre for Mathematics of the University of Porto, Rua Dr António Bernardino de Almeida, 431, 4200-072 Porto, Portugal. Electronic address: cap@isep.ipp.pt.
authors.forename: Carla M A
authors.initials: CM
authors.lastname: Pinto
mesh_terms: D015658:HIV Infections / Q000150:complications*; D006526:Hepatitis C / Q000150:complications*; D006801:Humans; D008962:Models, Theoretical
keywords: Coinfection; HCV; HIV/AIDS; Mathematical model