title: Left ventricular mechanics in Behcet's disease: a speckle tracking echocardiographic study.
abstract: Although cardiac involvement is rarely seen in Behcet's disease (BD), it is essential to detect subclinical left ventricular (LV) dysfunction for prognostic purposes. Herein we aimed to show the role of two dimensional (2D) speckle tracking echocardiography (STE) in determination of subclinical LV dysfunction in patients with BD. 30 patients diagnosed as BD due to International Study Group Behcet's diagnostic criteria and 25 control subjects underwent Doppler echocardiography including pulsed tissue Doppler of the mitral annulus and speckle-tracking echocardiography. LV peak longitudinal strain and strain rate (SR) was calculated in four-chamber (4C), apical long-axis (LAX), and two-chamber (2C) views, and values of the three views were averaged LV global longitudinal strain (LV-GLS) and SR. LV torsion was determined as the net difference in the mean rotation between the apical and basal levels. There was not any significant difference in age and gender between groups. Patients with BD had significantly lower LV longitudinal strain and Sr measurements than the control group. Although LV basal rotation (LVR) basal values were similar in both groups, LVR-apical and LV torsion (LVTR) values were significantly higher in patient group. LVR-apical and LV-GLS were found to have a good positive corelation (r:0.44, p<0.001) (r: -0.56, r: -0.65,respectively. p<0.001). There was a weak positive correlation between LVTR and LV-GLS (r: 0.29, p<0.05). We demonstrated that combined assessment of LV-GLS, LV-GLSR, LVTR and LVR-apical values detected by STE can be useful in determination of subclinical left ventricular dysfunction in BD.
authors.affiliation: Department of Cardiology, Erzurum Education and Research Hospital, Erzurum. demirelli23@yahoo.com.
authors.forename: Selami
authors.initials: S
authors.lastname: Demirelli
authors.forename: Hüsnü
authors.initials: H
authors.lastname: Degirmenci
authors.forename: Handan
authors.initials: H
authors.lastname: Bilen
authors.forename: Emrah
authors.initials: E
authors.lastname: Ermis
authors.forename: Hakan
authors.initials: H
authors.lastname: Duman
authors.forename: Arif
authors.initials: A
authors.lastname: Arisoy
authors.forename: Eftal Murat
authors.initials: EM
authors.lastname: Bakirci
authors.forename: Emrah
authors.initials: E
authors.lastname: Ipek
authors.forename: Lutfu
authors.initials: L
authors.lastname: Askin
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D004452:Echocardiography / Q000379:methods*; D015150:Echocardiography, Doppler; D005260:Female; D006339:Heart Rate; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D006801:Humans; D008297:Male; D015588:Observer Variation; D012399:Rotation; D012680:Sensitivity and Specificity; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging / Q000503:physiopathology; D016277:Ventricular Function, Left; D055815:Young Adult