title: Stereoselective C-H borylations of cyclopropanes and cyclobutanes with silica-supported monophosphane-Ir catalysts.
abstract: Heteroatom-directed C-H borylation of cyclopropanes and cyclobutanes was achieved with silica-supported monophosphane-Ir catalysts. Borylation occurred at the C-H bonds located γ to the directing N or O atoms with exceptional cis stereoselectivity relative to the directing groups. This protocol was applied to the borylation of a tertiary C-H bond of a ring-fused cyclopropane.
authors.affiliation: Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810 (Japan).
authors.forename: Ryo
authors.initials: R
authors.lastname: Murakami
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Tsunoda
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Iwai
authors.forename: Masaya
authors.initials: M
authors.lastname: Sawamura
mesh_terms: D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D018360:Crystallography, X-Ray; D003503:Cyclobutanes / Q000737:chemistry*; D003521:Cyclopropanes / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry; D007495:Iridium / Q000737:chemistry*; D008968:Molecular Conformation; D010720:Phosphines / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D003503:Cyclobutanes; D003521:Cyclopropanes; D010720:Phosphines; D007495:Iridium; D002244:Carbon; D012822:Silicon Dioxide; D006859:Hydrogen; C030797:cyclopropane; C044646:phosphine
keywords: CH activation; borylation; cyclobutanes; cyclopropanes; iridium catalysts