title: Rectal prolapse and cystic fibrosis.
abstract: Screening for cystic fibrosis (CF) is suggested in patients with rectal prolapse (RP). Little is known about the association between CF and RP in the era of newborn screening for CF. Our retrospective review showed that 3.6% of patients with RP had CF, and 3.5% of patients with CF had RP. No demographic or clinical factors appear to predict the likelihood of RP in patients with CF. Sweat chloride testing for patients with RP has a low yield in the era of newborn screening but may still need to be considered in children with RP to avoid missing the rare child with CF.
authors.affiliation: *Mercy Medical Center, Department of Pediatrics, Pediatric Gastroenterology, Hepatology and Nutrition, Des Moines, IA †Division of Pediatric Pulmonology, Department of Pediatrics, Makassed Hospital, Jerusalem, Israel ‡Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Boston University, Boston, MA §Division of Pediatric Pulmonology, Department of Pediatrics ||Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Medical College of Wisconsin, Milwaukee.
authors.forename: Khalil I
authors.initials: KI
authors.lastname: El-Chammas
authors.forename: Nisreen
authors.initials: N
authors.lastname: Rumman
authors.forename: Vi Lier
authors.initials: VL
authors.lastname: Goh
authors.forename: Diana
authors.initials: D
authors.lastname: Quintero
authors.forename: Praveen S
authors.initials: PS
authors.lastname: Goday
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002712:Chlorides / Q000032:analysis; D003550:Cystic Fibrosis / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D015997:Neonatal Screening; D010179:Pancreas / Q000503:physiopathology; D012005:Rectal Prolapse / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D012189:Retrospective Studies; D012307:Risk Factors; D013542:Sweat / Q000737:chemistry; D014922:Wisconsin / Q000453:epidemiology
chemical_list: D002712:Chlorides