title: Direct comparison of Neuroform and Enterprise stents in the treatment of wide-necked intracranial aneurysms.
abstract: OBJECTIVE
  To compare the complications and outcomes of Neuroform and Enterprise stents in the treatment of unruptured wide-necked aneurysms.
  
  
  METHODS
  Under the auspices of the institutional review board, a review of a prospectively collected patient log identified 130 patients who underwent elective stent-assisted coil embolization of a wide-necked aneurysm, including 53 patients treated with an Enterprise stent and 77 patients treated with a Neuroform stent. Immediate and long-term clinical and radiographic outcomes were recorded for all patients. All patient data were handled in accordance with Health Insurance Portability and Accountability Act of 1996 (HIPAA) regulations.
  
  
  RESULTS
  The technical success rate was 94%. Overall morbidity was 15% with Enterprise stents and 3% with Neuroform stents (p = 0.020). However, the type of stent used was not predictive of clinical outcomes as measured by the modified Rankin scale. In a multivariate analysis, the use of a Neuroform stent was one of the predictors of retreatment (p = 0.034).
  
  
  CONCLUSIONS
  Multivariate analyses identified the use of Neuroform stents as an independent predictor of the need for retreatment and the use of Enterprise stents as an independent predictor of morbidity. However, the type of stent was not predictive of clinical outcome as measured by the modified Rankin scale.
authors.affiliation: Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, USA. Electronic address: cdurst@virginia.edu.
authors.forename: C R
authors.initials: CR
authors.lastname: Durst
authors.affiliation: Batra Hospital and Medical Research Centre, New Delhi, India.
authors.forename: P
authors.initials: P
authors.lastname: Khan
authors.affiliation: Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, USA.
authors.forename: J
authors.initials: J
authors.lastname: Gaughen
authors.affiliation: Department of Public Health Services, University of Virginia, Charlottesville, VA, USA.
authors.forename: J
authors.initials: J
authors.lastname: Patrie
authors.affiliation: Department of Neurosurgery, University of Virginia, Charlottesville, VA, USA.
authors.forename: R M
authors.initials: RM
authors.lastname: Starke
authors.affiliation: Department of Cardiology, University of Virginia, Charlottesville, VA, USA.
authors.forename: P
authors.initials: P
authors.lastname: Conant
authors.affiliation: Department of Neurosurgery, University of Virginia, Charlottesville, VA, USA.
authors.forename: K C
authors.initials: KC
authors.lastname: Liu
authors.affiliation: Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, USA.
authors.forename: M E
authors.initials: ME
authors.lastname: Jensen
authors.affiliation: Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, USA.
authors.forename: A J
authors.initials: AJ
authors.lastname: Evans
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015901:Angiography, Digital Subtraction / Q000379:methods; D004621:Embolization, Therapeutic / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000209:etiology; D011446:Prospective Studies; D019233:Retreatment / Q000706:statistics & numerical data; D015607:Stents / Q000009:adverse effects / Q000145:classification* / Q000706:statistics & numerical data*; D016896:Treatment Outcome; D055815:Young Adult