title: 53BP1 regulates pRB via a lysine methylation-dependent interaction.
abstract: 53BP1 integrates pRB activity with the DNA damage response by binding to methylated K810.
mesh_terms: D000818:Animals; D002868:Chromosomal Proteins, Non-Histone / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000378:metabolism*; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism*; D008239:Lysine / Q000378:metabolism*; D016160:Retinoblastoma Protein / Q000378:metabolism*
chemical_list: D002868:Chromosomal Proteins, Non-Histone; D004268:DNA-Binding Proteins; D047908:Intracellular Signaling Peptides and Proteins; D016160:Retinoblastoma Protein; D008239:Lysine