title: Low-grade gliomas: the challenges of imaging.
abstract: WHO grade II gliomas are a major challenge for magnetic resonance imaging (MRI) due to their delayed anaplastic transformation. Today it is possible to individually characterize tumor progression from diagnosis to anaplastic transformation based on the many parameters identified in studies in the literature and the possibility of integrating these data into mathematical models. Early identification of negative morphological and metabolic factors, as well as treatment follow-up, help identify predictive factors of tumor progression, as well as determine treatment response to adapt management of this disease.
authors.affiliation: Laboratoire DACTIM, service de radiologie, université de Poitiers, centre hospitalier universitaire de Poitiers, 2, rue de la Milétrie, 86021 Poitiers, France. Electronic address: remy.guillevin@chu-poitiers.fr.
authors.forename: R
authors.initials: R
authors.lastname: Guillevin
authors.affiliation: Laboratoire DACTIM, service de radiologie, université de Poitiers, centre hospitalier universitaire de Poitiers, 2, rue de la Milétrie, 86021 Poitiers, France.
authors.forename: G
authors.initials: G
authors.lastname: Herpe
authors.affiliation: Laboratoire DACTIM, service de radiologie, université de Poitiers, centre hospitalier universitaire de Poitiers, 2, rue de la Milétrie, 86021 Poitiers, France.
authors.forename: M
authors.initials: M
authors.lastname: Verdier
authors.affiliation: Laboratoire DACTIM, service de radiologie, université de Poitiers, centre hospitalier universitaire de Poitiers, 2, rue de la Milétrie, 86021 Poitiers, France.
authors.forename: C
authors.initials: C
authors.lastname: Guillevin
mesh_terms: D001932:Brain Neoplasms / Q000098:blood supply / Q000175:diagnosis* / Q000473:pathology; D003952:Diagnostic Imaging / Q000379:methods*; D018450:Disease Progression; D042241:Early Diagnosis; D005910:Glioma / Q000098:blood supply / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D055420:Perfusion Imaging / Q000379:methods; D011379:Prognosis; D047368:Tumor Burden
keywords: Low-grade gliomas; MRI; Perfusion imaging; Spectroscopy; Therapeutic follow-up