title: Delayed diagnosis of clear cell chondrosarcoma after total hip replacement. A case report of a rare entity encountered in common surgery.
abstract: We report the case of a young female patient who received a total hip replacement due to pain in her left hip joint, misdiagnosed as degenerative arthritis. A clear cell chondrosarcoma (CCCS) in the femoral head had initially not been detected. Seven years later, a periprosthetic recurrence of CCCS close to the former femoral osteotomy occurred. Although a sample of the periprosthetic tumour had been taken for histologic analysis, the recurrence of CCCS remained misdiagnosed for almost 2 years until this rare histopathologic morphology was examined in a specialised multidisciplinary tumour centre. Finally, revision surgery with wide tumour resection margins had to be performed requiring the removal of the total hip replacement and its reconstruction using a modular megaimplant (proximal femoral replacement). Relevant facts of the CCCS as a rare entity regarding histology, treatment and differential diagnoses are discussed.
authors.affiliation: 1 Department of Orthopaedics and Sport Orthopaedics, Technische Universitaet Muenchen, Klinikum Rechts der Isar, Munich - Germany.
authors.forename: Franz
authors.initials: F
authors.lastname: Liska
authors.forename: Andreas
authors.initials: A
authors.lastname: Toepfer
authors.forename: Melanie
authors.initials: M
authors.lastname: Straub
authors.forename: Hans
authors.initials: H
authors.lastname: Rechl
authors.forename: Ruediger
authors.initials: R
authors.lastname: von Eisenhart-Rothe
mesh_terms: D000328:Adult; D019644:Arthroplasty, Replacement, Hip; D001859:Bone Neoplasms / Q000150:complications / Q000175:diagnosis*; D002813:Chondrosarcoma / Q000150:complications / Q000175:diagnosis*; D057210:Delayed Diagnosis; D003937:Diagnosis, Differential; D005260:Female; D005272:Femur Neck; D006801:Humans; D015207:Osteoarthritis, Hip / Q000150:complications / Q000601:surgery*; D011184:Postoperative Period; D014057:Tomography, X-Ray Computed