title: Factor analysis of biochemical markers associated with bone mineral density in adults.
abstract: [Purpose] The aim of this study was to find biochemical markers related to low bone mineral density in Korean adults. [Subjects and Methods] From August 1 to September 15, 2013, subjects receiving medical checkups were classified as lumbar spine bone normal, osteopenic, or osteoporotic using a bone mineral densitometer. Next, age, body mass index, and biochemical parameter differences were compared among the three groups. [Results] The results revealed that, the relevant factors were maximum blood pressure, minimum blood pressure, bone mineral density, total bilirubin, alkaline phosphatase (ALP), fasting blood glucose, iron, neutrophils, monocytes, and eosinophils. The bone mineral density of patients with osteoporosis was 0.763 times lower than that of normal subjects. The total bilirubin level of patients with osteoporosis was 0.45 times lower than that of normal subjects. The alkaline phosphatase level of patients with osteopenia was 1.059 times higher than that of normal subjects, and that in patients with osteoporosis was 1.088 times higher than that in normal subjects. The fasting blood glucose level of patients with osteoporosis was 0.963 times lower than that of normal subjects. The iron level of patients with osteoporosis was 0.986 times lower than that of normal subjects. [Conclusion] In conclusion, osteoporosis is a representative disease in elderly women due to aging and menopause, and more active interest should be taken for prevention and treatment.
authors.affiliation: Department of International Radiological Science, Hallym University of Graduate Studies, Republic of Korea.
authors.forename: Jae-Hwan
authors.initials: JH
authors.lastname: Cho
authors.affiliation: Department of International Radiological Science, Hallym University of Graduate Studies, Republic of Korea.
authors.forename: Min-Tae
authors.initials: MT
authors.lastname: Kim
authors.affiliation: Department of Computer Science and Engineering, Soonchunhyang University, Republic of Korea.
authors.forename: Hae-Kag
authors.initials: HK
authors.lastname: Lee
authors.affiliation: Department of Computer Science and Engineering, Soonchunhyang University, Republic of Korea.
authors.forename: In-Sik
authors.initials: IS
authors.lastname: Hong
authors.affiliation: Department of Radiological Science, Suseong College, Republic of Korea ; Department of Public Health, Hanyang University, Republic of Korea.
authors.forename: Hyon-Chol
authors.initials: HC
authors.lastname: Jang
keywords: Bone mineral density; Osteopenia; Osteoporosis