title: Hydrophobic triaryl-substituted β-lactams as activity-based probes for profiling eukaryotic enzymes and host-pathogen interactions.
authors.affiliation: Life Sciences Division, National Research Council of Canada, 100 Sussex Drive, Ottawa, ON, K1A 0R6 (Canada); Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5 (Canada).
authors.forename: Neda
authors.initials: N
authors.lastname: Nasheri
authors.forename: Craig S
authors.initials: CS
authors.lastname: McKay
authors.forename: Kelly
authors.initials: K
authors.lastname: Fulton
authors.forename: Susan
authors.initials: S
authors.lastname: Twine
authors.forename: Megan H
authors.initials: MH
authors.lastname: Powdrill
authors.forename: Allison R
authors.initials: AR
authors.lastname: Sherratt
authors.forename: John Paul
authors.initials: JP
authors.lastname: Pezacki
mesh_terms: D045744:Cell Line, Tumor; D004798:Enzymes / Q000737:chemistry* / Q000378:metabolism; D005057:Eukaryotic Cells / Q000201:enzymology* / Q000378:metabolism / Q000382:microbiology; D054884:Host-Pathogen Interactions; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D008968:Molecular Conformation; D015335:Molecular Probes / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism; D047090:beta-Lactams / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism
chemical_list: D004798:Enzymes; D015335:Molecular Probes; D047090:beta-Lactams
keywords: activity-based protein profiling; beta-lactams; eukaryote; hepatitis C virus; mass spectrometry