title: Social cognition and functional capacity in bipolar disorder and schizophrenia.
abstract: Social cognition is a functionally relevant predictor of capacity in schizophrenia (SZ), though research concerning its value for bipolar disorder (BD) is limited. The current investigation examined the relationship between two social cognitive factors and functional capacity in bipolar disorder. This study included 48 individuals with bipolar disorder (24 with psychotic features) and 30 patients with schizophrenia. Multiple regression controlling for estimated IQ scores was used to assess the predictive value of social cognitive factors on the UCSD Performance-Based Functional Skills Assessment (UPSA). Results found that for the bipolar with psychosis and schizophrenia groups, the social/emotion processing factor predicted the UPSA. The theory of mind factor only predicted the UPSA for the schizophrenia group.. Findings support the clinical utility of evaluating emotion processing in individuals with a history of psychosis. For BD, theory of mind may be better explained by a generalized cognitive deficit. In contrast, social/emotion processing may be linked to distinct neurobiological processes associated with psychosis.
authors.affiliation: Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USA. Electronic address: nthaler@mednet.ucla.edu.
authors.forename: Nicholas S
authors.initials: NS
authors.lastname: Thaler
authors.affiliation: Department of Psychology, University of North Carolina, Wilmington, Wilmington, NC, USA.
authors.forename: Griffin P
authors.initials: GP
authors.lastname: Sutton
authors.affiliation: Department of Psychology, University of Nevada, Las Vegas, Las Vegas, NV, USA.
authors.forename: Daniel N
authors.initials: DN
authors.lastname: Allen
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000175:diagnosis / Q000523:psychology*; D003071:Cognition / Q000502:physiology; D004644:Emotions / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D012559:Schizophrenia / Q000175:diagnosis*; D012565:Schizophrenic Psychology; D012919:Social Behavior; D055815:Young Adult
keywords: Bipolar disorder; Functional capacity; Schizophrenia; Social cognition