title: Evaluation of sodium cantharidinate/vitamin B6 in the treatment of primary liver cancer.
abstract: OBJECTIVE
  The present study evaluated the treatment effectiveness of sodium cantharidinate/vitamin B6 in patient with middle/late stage primary liver cancer.
  
  
  METHODS
  A 3-month follow-up study on 104 patients with primary liver cancer was carried out. Regular medication treatment was applied to 41 patients and sodium cantharidinate/vitamin B6 combined with the regular medication was applied to 63 patients. The treatment effectiveness and prognosis were evaluated using the statistical methods.
  
  
  RESULTS
  At the end of the treatment, no significant difference was detected between the two groups; 1-month follow-up survey showed that in the treatment group, the death rate was lower, the treatment gain was maintained longer and the tumor morphology was maintained better, compared with the control group; 3-month follow-up study showed that there was not significance difference between the two groups.
  
  
  CONCLUSIONS
  Sodium cantharidinate/vitamin B6 might be used as auxiliary drug in patients with primary liver cancer and could improve the treatment outcomes for a short-term period.
authors.forename: Hejun
authors.initials: H
authors.lastname: Shao
authors.forename: Guohu
authors.initials: G
authors.lastname: Hong
authors.affiliation: Department of Infection Diseases, Guizhou Provincial People's Hospital, Guiyang, Guizhou, China.
authors.forename: Xinhua
authors.initials: X
authors.lastname: Luo
mesh_terms: D000328:Adult; D002193:Cantharidin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D064420:Drug-Related Side Effects and Adverse Reactions / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D025101:Vitamin B 6 / Q000008:administration & dosage* / Q000009:adverse effects
chemical_list: C027130:disodium cantharidin; D025101:Vitamin B 6; D002193:Cantharidin