title: Protective effects of Moringa oleifera Lam. leaves against arsenic-induced toxicity in mice.
abstract: OBJECTIVE
  To evaluate the protective role of leaves of Moringa oleifera (M. oleifera) Lam. against arsenic-induced toxicity in mice.
  
  
  METHODS
  Swiss albino male mice were divided into four groups. The first group was used as non-treated control group while, the second, third, and fourth groups were treated with M. oleifera leaves (50 mg/kg body weight per day), sodium arsenite (10 mg/kg body weight per day) and sodium arsenite plus M. oleifera leaves, respectively. Serum indices related to cardiac, liver and renal functions were analyzed to evaluate the protective effect of Moringa leaves on arsenic-induced effects in mice.
  
  
  RESULTS
  It revealed that food supplementation of M. oleifera leaves abrogated the arsenic-induced elevation of triglyceride, glucose, urea and the activities of alkaline phospatase, aspartate aminotransferase and alanine aminotransferase in serum. M. oleifera leaves also prevented the arsenic-induced perturbation of serum butyryl cholinesterase activity, total cholesterol and high density lipoprotein cholesterol.
  
  
  CONCLUSIONS
  The results indicate that the leaves of M. oleifera may be useful in reducing the effects of arsenic-induced toxicity.
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
authors.forename: Afzal
authors.initials: A
authors.lastname: Sheikh
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
authors.forename: Fouzia
authors.initials: F
authors.lastname: Yeasmin
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
authors.forename: Smita
authors.initials: S
authors.lastname: Agarwal
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
authors.forename: Mashiur
authors.initials: M
authors.lastname: Rahman
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
authors.forename: Khairul
authors.initials: K
authors.lastname: Islam
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
authors.forename: Ekhtear
authors.initials: E
authors.lastname: Hossain
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
authors.forename: Shakhawoat
authors.initials: S
authors.lastname: Hossain
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
authors.forename: Md Rezaul
authors.initials: MR
authors.lastname: Karim
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
authors.forename: Farjana
authors.initials: F
authors.lastname: Nikkon
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
authors.forename: Zahangir Alam
authors.initials: ZA
authors.lastname: Saud
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
authors.forename: Khaled
authors.initials: K
authors.lastname: Hossain
keywords: Arsenic toxicity; Moringa oleifera leaves; Serum indices