title: [Awake intubation with landiolol and dexmedetomidine in a patient with anxiety neurosis].
abstract: We report a successful case of awake intubation in a patient with anxiety neurosis via continuous administration of landiolol and dexmedetomidine. A 52-year-old woman weighing 46.8 kg with anxiety neurosis experienced postoperative bleeding after left-side thyroidectomy and was scheduled for emergent hemostasis under general anesthesia Due to swelling of the neck, we anticipated a difficult airway and decided to perform awake intubation. She showed extreme insecurity and shivering, and initially did not agree to the procedure. To calm her anxiety and panic, we continuously administered 10 microg x kg(-1). min(-1) landiolol and 1.0 microg x kg(-1) hr(-1) dexmedetomidine. After 10 minutes, her shivering disappeared, and she agreed to undergo awake intubation, which was performed with the Pentax-AWS Airwayscope and thin Intlock blade. The patient bucked slightly during intubation but hemodynamic changes were minimal.
authors.forename: Tatsunari
authors.initials: T
authors.lastname: Nagamine
authors.forename: Nobuyasu
authors.initials: N
authors.lastname: Komasawa
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Fujitate
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Kuzukawa
authors.forename: Manabu
authors.initials: M
authors.lastname: Kitano
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Minami
mesh_terms: D000768:Anesthesia, General; D001007:Anxiety; D001008:Anxiety Disorders / Q000188:drug therapy* / Q000523:psychology; D020927:Dexmedetomidine / Q000008:administration & dosage*; D004630:Emergencies; D005260:Female; D006488:Hemostasis, Surgical; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D007442:Intubation, Intratracheal / Q000295:instrumentation / Q000379:methods*; D020704:Laryngoscopes; D008875:Middle Aged; D009025:Morpholines / Q000008:administration & dosage*; D019106:Postoperative Hemorrhage / Q000601:surgery; D013965:Thyroidectomy; D014508:Urea / Q000008:administration & dosage / Q000031:analogs & derivatives*; D014851:Wakefulness
chemical_list: D006993:Hypnotics and Sedatives; D009025:Morpholines; C077049:landiolol; D020927:Dexmedetomidine; D014508:Urea