title: Spectral-domain optical coherence tomography findings after severe exogenous endophthalmitis.
abstract: OBJECTIVE
  To report outcomes and assess structural changes in the retina in patients with severe endophthalmitis.
  
  
  METHODS
  Retrospective, nonrandomized, interventional case series at a tertiary referral centre. Spectral domain optical coherence tomography (OCT) images of both eyes were acquired at least 5 months after pars plana vitrectomy. OCT images were analyzed using retinal layer segmentation.
  
  
  RESULTS
  Nine patients (46-80 years of age) were included in this study. Average ETDRS visual acuity before treatment was 23 letters and improved to 74 letters. In our cohort we did not find a generalized reduction of retinal layers using automated layer segmentation.
  
  
  CONCLUSIONS
  Our findings suggest that prompt treatment of severe endophthalmitis with intravitreal antibiotics followed by pars plana vitrectomy may lead to excellent visual outcomes with minimal damage to the retinal architecture.
authors.affiliation: Department of Ophthalmology, University of Bern , Bern , Switzerland.
authors.forename: Martin Sebastian
authors.initials: MS
authors.lastname: Zinkernagel
authors.forename: Chantal
authors.initials: C
authors.lastname: Dysli
authors.forename: Sebastian
authors.initials: S
authors.lastname: Wolf
authors.forename: Andreas
authors.initials: A
authors.lastname: Ebneter
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D009877:Endophthalmitis / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000473:pathology*; D012189:Retrospective Studies; D012720:Severity of Illness Index; D041623:Tomography, Optical Coherence / Q000379:methods*; D014792:Visual Acuity; D014821:Vitrectomy
keywords: Endophthalmitis; OCT; retina; segmentation