title: Genomic structure of the Aeromonas bacteriophage pAh6-C and its comparative genomic analysis.
abstract: pAh6-C is a virulent bacteriophage (phage), isolated from a river in Korea, that infects a multiple-antibiotic-resistant A. hydrophila strain, JUNAH. The double-stranded DNA genome of pAh6-C is composed of 53,744 bp with a G + C content of 52.83 %. The genome encodes 86 putative ORFs, four putative promoters, and seven transcriptional terminator regions. Genome sequence analysis of pAh6-C and comparative analysis with the homologous Shewanella phage Spp001 revealed that there is a high degree of similarity between pAh6-C and Spp001 in 50 of the 86 ORFs of pAh6-C. The results of this investigation indicate that pAh6-C is closely related to Spp001, especially in the genes coding for proteins involved in DNA metabolism.
authors.affiliation: Institute of Marine Biology, Biotechnology and Aquaculture, Hellenic Centre for Marine Research, Former American Base of Gournes, Heraklion, 71003, Crete, Greece.
authors.forename: Jin Woo
authors.initials: JW
authors.lastname: Jun
authors.forename: Hyoun Joong
authors.initials: HJ
authors.lastname: Kim
authors.forename: Sae Kil
authors.initials: SK
authors.lastname: Yun
authors.forename: Ji Young
authors.initials: JY
authors.lastname: Chai
authors.forename: Se Chang
authors.initials: SC
authors.lastname: Park
mesh_terms: D000333:Aeromonas / Q000821:virology*; D000595:Amino Acid Sequence; D000818:Animals; D001435:Bacteriophages / Q000235:genetics*; D001483:Base Sequence; D002874:Chromosome Mapping; D004279:DNA, Viral / Q000235:genetics*; D005393:Fish Diseases / Q000382:microbiology; D016679:Genome, Viral / Q000235:genetics*; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology / Q000662:veterinary; D008969:Molecular Sequence Data; D017900:Myoviridae / Q000235:genetics*; D011401:Promoter Regions, Genetic; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid; D014764:Viral Proteins / Q000235:genetics
chemical_list: D004279:DNA, Viral; D014764:Viral Proteins