title: Clinical validation of a low-power and wearable ECG patch for long term full-disclosure monitoring.
abstract: BACKGROUND
  Detection of intermittent atrial fibrillation (AF) is done using a 24-h Holter. Holter recordings are powerful but lack the comfort and have limited recording times resulting in under diagnosing of intermittent AF.
  
  
  OBJECTIVE
  Within this work we evaluated and compared a novel miniaturized three-channel ECG monitoring patch versus a 24-h Holter system.
  
  
  METHODS
  Both patients with a chronic AF rhythm (n=5) as well as patients with an AF rhythm that underwent electrical reconversion (n = 5) were equipped with both a 24-h Holter and ECG patch.
  
  
  RESULTS
  Alignment of raw data of both ECG systems allowed cross-correlation analysis. Overall good correlations of up to 85% were obtained. RR-interval analysis of both systems resulted in very high correlations of 99% and higher. AF analysis showed correct identification of AF on both ECG systems.
  
  
  CONCLUSIONS
  The performance of our ECG patch matches that of the 24-h Holter and could provide a suitable tool for long-term monitoring applications.
authors.affiliation: Imec, Kapeldreef 75, Heverlee, Leuven, Belgium.
authors.forename: Tom
authors.initials: T
authors.lastname: Torfs
authors.affiliation: Department of Cardiology, Ziekenhuis Oost-Limburg, Schiepse Bos 6, Genk, Belgium; Faculty of Medicine and Life Sciences, Hasselt University, Martelarenlaan 42, Hasselt, Belgium.
authors.forename: Christophe J P
authors.initials: CJ
authors.lastname: Smeets
authors.affiliation: Imec the Netherlands, Holst Centre, High Tech Campus 31, Eindhoven, The Netherlands.
authors.forename: Di
authors.initials: D
authors.lastname: Geng
authors.affiliation: Imec the Netherlands, Holst Centre, High Tech Campus 31, Eindhoven, The Netherlands.
authors.forename: Torfinn
authors.initials: T
authors.lastname: Berset
authors.affiliation: Department of Cardiology, Ziekenhuis Oost-Limburg, Schiepse Bos 6, Genk, Belgium; Faculty of Medicine and Life Sciences, Hasselt University, Martelarenlaan 42, Hasselt, Belgium.
authors.forename: Jo
authors.initials: J
authors.lastname: Van der Auwera
authors.affiliation: Department of Cardiology, Ziekenhuis Oost-Limburg, Schiepse Bos 6, Genk, Belgium; Faculty of Medicine and Life Sciences, Hasselt University, Martelarenlaan 42, Hasselt, Belgium.
authors.forename: Pieter
authors.initials: P
authors.lastname: Vandervoort
authors.affiliation: Department of Cardiology, Ziekenhuis Oost-Limburg, Schiepse Bos 6, Genk, Belgium; Faculty of Medicine and Life Sciences, Hasselt University, Martelarenlaan 42, Hasselt, Belgium; Imec the Netherlands, Holst Centre, High Tech Campus 31, Eindhoven, The Netherlands. Electronic address: lars.grieten@zol.be.
authors.forename: Lars
authors.initials: L
authors.lastname: Grieten
mesh_terms: D001281:Atrial Fibrillation / Q000175:diagnosis*; D011211:Electric Power Supplies; D015716:Electrocardiography, Ambulatory / Q000295:instrumentation*; D004735:Energy Transfer; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D008904:Miniaturization; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation; D059015:Wireless Technology / Q000295:instrumentation*
keywords: ECG; ECG patch; Full disclosure; Holter; Low power