title: Large capsulorhexis with implantation of a 7.0 mm optic intraocular lens during cataract surgery in patients with diabetes mellitus.
abstract: OBJECTIVE
  To evaluate the efficacy of a large capsulorhexis and intraocular lens (IOL) in obtaining a larger anterior capsule opening after cataract surgery in patients with diabetes mellitus (DM).
  
  
  METHODS
  Department of Ophthalmology, University of Fukui, Fukui, Japan.
  
  
  METHODS
  Prospective clinical trial.
  
  
  METHODS
  Patients with DM had bilateral cataract surgery with a 2.8 or 3.0 mm scleral incision, a capsulorhexis with a diameter of approximately 5.0 or 6.0 mm, and implantation of a 6.0 mm optic (Eternity X-60) or 7.0 mm optic (Eternity X-70) IOL. The anterior capsule opening area, aqueous flare intensity, surgically induced astigmatism (SIA), corneal endothelial cell density (ECD), and central corneal thickness (CCT) were measured 1 day, 1 week, and 1, 3, and 6 months after surgery.
  
  
  RESULTS
  Thirty-one patients (62 eyes) with DM were enrolled. At all postoperative timepoints, the anterior capsule opening was significantly larger in eyes with the 7.0 mm optic IOL than in eyes with the 6.0 mm optic IOL (P<.05, Mann-Whitney U test). There were no significant differences in postoperative aqueous flare intensity, SIA, ECD, or CCT based on the size of the capsulorhexis and IOL.
  
  
  CONCLUSIONS
  A larger capsulorhexis and implantation of a 7.0 mm IOL resulted in a larger anterior capsule opening after cataract surgery in patients with DM.
  
  
  BACKGROUND
  No author has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: From the Department of Ophthalmology (Takamura, Tomomatsu, Yokota, Matsumura, Takihara, Inatani), Faculty of Medical Sciences, University of Fukui, Fukui, and the Department of Ophthalmology and Visual Sciences (Yokota), Kyoto University Graduate School of Medicine, Kyoto, Japan. Electronic address: ytakamura@hotmail.com.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Takamura
authors.affiliation: From the Department of Ophthalmology (Takamura, Tomomatsu, Yokota, Matsumura, Takihara, Inatani), Faculty of Medical Sciences, University of Fukui, Fukui, and the Department of Ophthalmology and Visual Sciences (Yokota), Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Tomomatsu
authors.affiliation: From the Department of Ophthalmology (Takamura, Tomomatsu, Yokota, Matsumura, Takihara, Inatani), Faculty of Medical Sciences, University of Fukui, Fukui, and the Department of Ophthalmology and Visual Sciences (Yokota), Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yokota
authors.affiliation: From the Department of Ophthalmology (Takamura, Tomomatsu, Yokota, Matsumura, Takihara, Inatani), Faculty of Medical Sciences, University of Fukui, Fukui, and the Department of Ophthalmology and Visual Sciences (Yokota), Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors.forename: Takehiro
authors.initials: T
authors.lastname: Matsumura
authors.affiliation: From the Department of Ophthalmology (Takamura, Tomomatsu, Yokota, Matsumura, Takihara, Inatani), Faculty of Medical Sciences, University of Fukui, Fukui, and the Department of Ophthalmology and Visual Sciences (Yokota), Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors.forename: Yuji
authors.initials: Y
authors.lastname: Takihara
authors.affiliation: From the Department of Ophthalmology (Takamura, Tomomatsu, Yokota, Matsumura, Takihara, Inatani), Faculty of Medical Sciences, University of Fukui, Fukui, and the Department of Ophthalmology and Visual Sciences (Yokota), Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors.forename: Masaru
authors.initials: M
authors.lastname: Inatani
mesh_terms: D000368:Aged; D057866:Anterior Capsule of the Lens / Q000473:pathology*; D001251:Astigmatism / Q000503:physiopathology; D058442:Capsule Opacification / Q000517:prevention & control; D019923:Capsulorhexis / Q000379:methods*; D002452:Cell Count; D055954:Corneal Endothelial Cell Loss / Q000503:physiopathology; D063171:Corneal Pachymetry; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D004728:Endothelium, Corneal / Q000473:pathology; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification / Q000379:methods; D011183:Postoperative Complications; D011446:Prospective Studies