title: Novel treatment in refractory tic douloureux.
abstract: A patient with refractory trigeminal neuralgia (tic douloureux) was treated by intravenous magnesium sulfate successfully. Parenteral magnesium sulfate is an analgesic that expresses its analgesic effects through a noncompetitive blockade of the N-methyl-D-aspartate (NMDA) receptors, which in turns inhibits calcium entry into the cells.
authors.affiliation: Cardiovascular Research Center, Tabriz University of Medical Sciences, Daneshgah St., Tabriz-51664, I.R., Iran. Electronic address: soleimanpourh@tbzmed.ac.ir.
authors.forename: Hassan
authors.initials: H
authors.lastname: Soleimanpour
authors.affiliation: Department of Anesthesiology and Critical Care, Tabriz University of Medical Sciences, Daneshgah St., Tabriz-51664, I.R., Iran.
authors.forename: Dawood
authors.initials: D
authors.lastname: Aghamohammadi
authors.affiliation: Department of Emergency Medicine, Tabriz University of Medical Sciences, Daneshgah St., Tabriz-51664, I.R., Iran.
authors.forename: Amir
authors.initials: A
authors.lastname: Ghaffarzad
authors.affiliation: Liver and Gastrointestinal Disease Research Center, Tabriz University of Medical Sciences, Daneshgah St., Tabriz-51664, I.R., Iran.
authors.forename: Samad Ej
authors.initials: SE
authors.lastname: Golzari
authors.affiliation: Department of Anesthesiology and Critical Care, Iran University of Medical Sciences, Tehran, I.R., Iran.
authors.forename: Saeid
authors.initials: S
authors.lastname: Safari
authors.affiliation: Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Daneshgah St., Tabriz-51664, I.R., Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Soleimanpour
mesh_terms: D000368:Aged; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D007275:Injections, Intravenous; D008278:Magnesium Sulfate / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D010148:Intractable Pain / Q000188:drug therapy / Q000209:etiology; D016194:Receptors, N-Methyl-D-Aspartate / Q000037:antagonists & inhibitors; D014277:Trigeminal Neuralgia / Q000150:complications / Q000188:drug therapy*
chemical_list: D018712:Analgesics, Non-Narcotic; D016194:Receptors, N-Methyl-D-Aspartate; D008278:Magnesium Sulfate
keywords: Emergency medicine department; Magnesium sulfate; Trigeminal neuralgia