title: [The effect of nasal irrigation in the treatment of allergic rhinitis].
abstract: OBJECTIVE
  To compare the symptoms and lower airway inflammatory factors of patients with allergic rhinitis (AR), and to observe the effect of nasal irrigation in the treatment of allergic rhinitis.
  
  
  METHODS
  Sixty-one cases diagnosed as AR after skin prick test (SPT)were selected and randomly divided into three groups: 17 patients in group A used nasal steroid spray; 21 cases in group B used nasal irrigation; 23 patients in group C combined ir rigation with nasal steroid. Before and after 3 months treatment, nasal visual analogue scale (VAS) score, rhino conjunctivtis quality of life questionnaire (RQLQ) score, fractional exhaled nitric oxide (FENO) values were observed and compared in each group.
  
  
  RESULTS
  Before treatment, there is no statistically difference between three groups (P > 0.05). After 3 months of treatment, VAS, RQLQ, FENO of all patients was significantly decreased (P < 0.05); VAS, RQLQ score was not significantly different among the three groups (P > 0.05), FENO value has no statistically significant difference between group A and group B (P > 0.05), but were less than that in group C (P < 0.05).
  
  
  CONCLUSIONS
  Nasal irrigation can ameliorate nasal symptoms, improve quality of life, decrease lower airway inflammation of allergic rhinitis patients. Nasal irrigation is an effective treatment of allergic rhinitis. Nasal irrigation combined with nasal steroid can achieve more significant efficacy.
authors.forename: Minghai
authors.initials: M
authors.lastname: Wu
authors.forename: Qiuping
authors.initials: Q
authors.lastname: Wang
authors.forename: Kai
authors.initials: K
authors.lastname: Zhang
authors.forename: Kunmin
authors.initials: K
authors.lastname: Wu
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhang
authors.forename: Zhiyi
authors.initials: Z
authors.lastname: Wang
authors.forename: Jun Feng
authors.initials: JF
authors.lastname: Ji
authors.forename: You
authors.initials: Y
authors.lastname: Cheng
authors.forename: Nanshan
authors.initials: N
authors.lastname: Zhong
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D055556:Nasal Lavage; D011788:Quality of Life; D065631:Rhinitis, Allergic / Q000628:therapy*; D016896:Treatment Outcome; D055815:Young Adult