title: Epidemiology and trend of cancer in Yazd, a central province of Iran, 2005-2009.
abstract: BACKGROUND
  Cancer incidence rate is increasing in the world particularly in developing countries. The awareness regarding cancer incidence and distribution helps policy makers and researchers to design comprehensive plan for controlling cancer. The aim of this study was to determine the incidence rate and trend of cancer in Yazd Province, central Iran.
  
  
  METHODS
  Data from Yazd cancer registry were derived from 2005 to 2009. Direct standardization through world standard population produced by the world health organization was used and Age- Standardized Incidence rate (ASR) was calculated. Data were analyzed using ASR, by EXCEL and SPSS software.
  
  
  RESULTS
  The new cases of cancer were 4631 patients from 2005 to 2009. Mean age of these patients was 57.98 ±27.49 years and 53.5% were male. Female patients were approximately 5 years younger than males. The most frequent cancer was breast in women followed by skin, colorectal, hematologic system and stomach. The 5 most frequent cancers in men were skin, bladder, colorectal, stomach and prostate. The ASR in 2005 to 2009 was respectively 85.2, 86.1, 92.6, 102.2 and 104.7 per 100,000 populations.
  
  
  CONCLUSIONS
  ASR of cancer is increasing rapidly in Yazd Province. It is necessary to have a comprehensive health policy for prevention and control of this problem.
authors.affiliation: Department of Community Medicine, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
authors.forename: Mahmood
authors.initials: M
authors.lastname: Vakili
authors.affiliation: Department of Community Medicine, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. azar_pirdehghan@yahoo.com.
authors.forename: Azar
authors.initials: A
authors.lastname: Pirdehghan
authors.affiliation: Department of Community Medicine, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
authors.forename: Meisam
authors.initials: M
authors.lastname: Adimi
authors.affiliation: Yazd Cancer Registry Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
authors.forename: Mohamadreza
authors.initials: M
authors.lastname: Sadeghian
authors.affiliation: Department of Internal Medicine, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
authors.forename: Mohsen
authors.initials: M
authors.lastname: Akhondi
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D015994:Incidence; D007492:Iran / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology*; D012042:Registries / Q000706:statistics & numerical data; D017678:Sex Distribution
keywords: Cancer; Epidemiology; Incidence; Iran