title: The coumarin-pterocarpan conjugate--a natural product inspired hybrid molecular probe for DNA recognition.
abstract: Thermally induced cascade sigmatropic rearrangement of a butynyloxycoumarin derivative has led to a quick access to the coumarin-pterocarpan hybrid molecule. Biophysical studies together with molecular modeling show that this nature-inspired hybrid molecule is capable of binding to the minor groove of DNA as a non-conventional entity.
authors.affiliation: Department of Chemistry, University of Kalyani, Kalyani, Nadia-742135, West Bengal, India. skchatto@yahoo.com.
authors.forename: Shital K
authors.initials: SK
authors.lastname: Chattopadhyay
authors.forename: Indranil
authors.initials: I
authors.lastname: Kundu
authors.forename: Ratnava
authors.initials: R
authors.lastname: Maitra
mesh_terms: D001688:Biological Products / Q000737:chemistry*; D003374:Coumarins / Q000737:chemistry*; D004247:DNA / Q000032:analysis*; D008958:Models, Molecular; D015335:Molecular Probes / Q000737:chemistry*; D015394:Molecular Structure; D036343:Pterocarpans / Q000737:chemistry*; D013696:Temperature
chemical_list: D001688:Biological Products; D003374:Coumarins; D015335:Molecular Probes; D036343:Pterocarpans; D004247:DNA; C030123:coumarin