title: Intraoperative parathyroid hormone monitoring in neonatal severe primary hyperparathyroidism.
abstract: Neonatal severe primary hyperparathyroidism presents in the first days of life with severe life-threatening hypercalcemia. It is associated with an inactivating homozygous mutation of the calcium sensing receptor gene. Total parathyroidectomy is the treatment of choice, so the surgeon must identify all the parathyroid tissue, including supernumerary and ectopic glands. We present the case of an infant who underwent total parathyroidectomy at age 4 months in which intraoperative parathyroid hormone monitoring provided immediate confirmation of surgical cure.
authors.affiliation: Virgen del Rocío Hospital, Sevilla, Spain ejgg67@gmail.com.
authors.forename: Emilio
authors.initials: E
authors.lastname: García-García
authors.affiliation: Virgen del Rocío Hospital, Sevilla, Spain.
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Domínguez-Pascual
authors.affiliation: Virgen del Rocío Hospital, Sevilla, Spain.
authors.forename: Mercedes
authors.initials: M
authors.lastname: Requena-Díaz
authors.affiliation: Virgen del Rocío Hospital, Sevilla, Spain.
authors.forename: Rosa
authors.initials: R
authors.lastname: Cabello-Laureano
authors.affiliation: Virgen del Rocío Hospital, Sevilla, Spain.
authors.forename: Israel
authors.initials: I
authors.lastname: Fernández-Pineda
authors.affiliation: Virgen del Rocío Hospital, Sevilla, Spain.
authors.forename: María J
authors.initials: MJ
authors.lastname: Sánchez-Martín
mesh_terms: D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000097:blood* / Q000175:diagnosis / Q000601:surgery*; D007223:Infant; D007232:Infant, Newborn, Diseases / Q000097:blood* / Q000175:diagnosis / Q000601:surgery*; D008297:Male; D016343:Monitoring, Intraoperative / Q000379:methods*; D010281:Parathyroid Hormone / Q000097:blood*
chemical_list: D010281:Parathyroid Hormone
keywords: hypercalcemia; neonatal severe primary hyperparathyroidism; parathyroid hormone