title: Multiple myeloma among Chornobyl accident clean-up workers - state and perspectives of analytical study.
abstract: The objective of the study was to analyze the Multiple Myeloma (MM) incidence in clean-up workers preparing the information background for consequent analytical study with a dose-dependent risk estimates.
  
  
  METHODS
  The Cohort Database was linked to the Ukrainian National Cancer Registry to identify the MM cases in a cohort of 152 520 male clean-up workers.
  
  
  RESULTS
  The 64 MM cases were identified in the studied Cohort for the 1987-2012 period. Fifty-eight of them were included to the preliminary incidence analysis accounting for the 10-years lag-period. According to the preliminary data analysis the MM incidence rate in studied clean-up workers Cohort did not exceed the corresponding rate in general population of Ukraine along the 21 years after the catastrophe.
  
  
  CONCLUSIONS
  Standardized incidence ratio for the 2008-2012 period, that is 22-26 years after the accident, demonstrated the significant excess of MM incidence among male clean-up workers in comparison with general population of Ukraine of corresponding age and gender (SIR 1.61, 95% CI 1.01;2.21).
authors.forename: D A
authors.initials: DA
authors.lastname: Bazyka
authors.forename: N A
authors.initials: NA
authors.lastname: Gudzenko
authors.forename: I S
authors.initials: IS
authors.lastname: Dyagil
authors.forename: N G
authors.initials: NG
authors.lastname: Babkina
authors.forename: V V
authors.initials: VV
authors.lastname: Chumak
authors.forename: E V
authors.initials: EV
authors.lastname: Bakhanova
authors.forename: V V
authors.initials: VV
authors.lastname: Paramonov
authors.forename: A Y
authors.initials: AY
authors.lastname: Romanenko
mesh_terms: D047852:Chernobyl Nuclear Accident; D015331:Cohort Studies; D004307:Dose-Response Relationship, Radiation; D052918:Environmental Restoration and Remediation; D006801:Humans; D015994:Incidence; D009101:Multiple Myeloma / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis / Q000453:epidemiology*; D009784:Occupational Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D016273:Occupational Exposure / Q000009:adverse effects* / Q000032:analysis; D011829:Radiation Dosage; D014455:Ukraine
keywords: Chornobyl accident; clean-up workers; incidence; multiple myeloma