title: Trauma history characteristics associated with mental states at clinical high risk for psychosis.
abstract: Traumatic experiences have been positively associated with both severity of attenuated psychotic symptoms in individuals at high risk (HR) for psychosis and transitions into psychotic disorders. Our aim was to determine what characteristics of the trauma history are more likely to be associated with individuals at HR. The Trauma History Screen (THS) was used to enable emphasis on number and perceived intensity of adverse life events and age at trauma exposure. Sixty help-seeking individuals who met HR criteria were compared to a random sample of 60 healthy volunteers. Both groups were aged 16-35 and resided in the same geographical location. HR participants experienced their first trauma at an earlier age, continued to experience trauma at younger developmental stages, especially during early/mid adolescence and were exposed to a high number of traumas. They were more depressed and anxious, but did not experience more distress in relation to trauma. Both incidences of trauma and age at which trauma occurred were the most likely predictors of becoming HR. This work emphasises the importance of assessing trauma characteristics in HR individuals to enable differentiation between psychotic-like experiences that may reflect dissociative responses to trauma and genuine prodromal psychotic presentations.
authors.affiliation: CAMEO Early Intervention in Psychosis Service, Cambridgeshire and Peterborough NHS Foundation Trust, UK; Department of Psychiatry, University of Cambridge, Cambridge, UK.
authors.forename: Debra A
authors.initials: DA
authors.lastname: Russo
authors.affiliation: CAMEO Early Intervention in Psychosis Service, Cambridgeshire and Peterborough NHS Foundation Trust, UK; Department of Psychiatry, University of Cambridge, Cambridge, UK.
authors.forename: Jan
authors.initials: J
authors.lastname: Stochl
authors.affiliation: CAMEO Early Intervention in Psychosis Service, Cambridgeshire and Peterborough NHS Foundation Trust, UK.
authors.forename: Michelle
authors.initials: M
authors.lastname: Painter
authors.affiliation: Department of Psychiatry, University of Cambridge, Cambridge, UK.
authors.forename: Veronika
authors.initials: V
authors.lastname: Dobler
authors.affiliation: CAMEO Early Intervention in Psychosis Service, Cambridgeshire and Peterborough NHS Foundation Trust, UK.
authors.forename: Erica
authors.initials: E
authors.lastname: Jackson
authors.affiliation: CAMEO Early Intervention in Psychosis Service, Cambridgeshire and Peterborough NHS Foundation Trust, UK; Department of Psychiatry, University of Cambridge, Cambridge, UK; NIHR Collaboration for Leadership in Applied Health Research & Care, Cambridge, UK.
authors.forename: Peter B
authors.initials: PB
authors.lastname: Jones
authors.affiliation: CAMEO Early Intervention in Psychosis Service, Cambridgeshire and Peterborough NHS Foundation Trust, UK; Department of Psychiatry, University of Cambridge, Cambridge, UK. Electronic address: jp440@cam.ac.uk.
authors.forename: Jesus
authors.initials: J
authors.lastname: Perez
mesh_terms: D000293:Adolescent; D000328:Adult; D001007:Anxiety / Q000523:psychology*; D003863:Depression / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000523:psychology; D012307:Risk Factors; D013313:Stress Disorders, Post-Traumatic / Q000523:psychology*; D055815:Young Adult
keywords: At-risk-mental-state; High-risk; Psychotic-like; Schizophrenia; Trauma