title: When the pathologist is giving the answer: an unusual case of pulmonary hypertension.
abstract: We report the case of a 75-years-old man who diagnosed with severe pulmonary hypertension, associated with interstitial lung disease characterized by a rapid and fatal outcome. Autopsy showed the presence of a signet-ring cell gastric carcinoma associated with pulmonary tumour embolism and pulmonary tumour thrombotic microangiopathy. Clinical features, diagnostics, therapy and prognosis are briefly discussed.
authors.affiliation: Innere Medizin, Ospedale Regionale di Lugano, sede Civico, Lugano.
authors.forename: Elia
authors.initials: E
authors.lastname: Lo Priore
authors.affiliation: Unità di Cure Palliative, Ospedale Regionale di Bellinzona.
authors.forename: Tanja
authors.initials: T
authors.lastname: Fusi-Schmidhauser
mesh_terms: D000368:Aged; D000792:Angiography; D018279:Carcinoma, Signet Ring Cell / Q000473:pathology* / Q000556:secondary*; D018450:Disease Progression; D004417:Dyspnea / Q000209:etiology; D004452:Echocardiography; D017809:Fatal Outcome; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology*; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000556:secondary*; D008209:Lymphedema / Q000209:etiology; D008297:Male; D061330:Multidetector Computed Tomography; D009360:Neoplastic Cells, Circulating / Q000473:pathology; D011655:Pulmonary Embolism / Q000175:diagnosis / Q000473:pathology; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000473:pathology*
keywords: Lungenhochdruck; Siegelzellringkarzinom; Tumorembolie; pulmonary tumour thrombotic microangiopathy; signet-ring cell gastric carcinoma; tumour embolism-pulmonary hypertension