title: Improving tuberculosis prevention and care through addressing the global diabetes epidemic: from evidence to policy and practice.
abstract: Diabetes triples the risk of tuberculosis and is also a risk factor for adverse tuberculosis treatment outcomes, including death. Prevalence of diabetes is increasing globally, but most rapidly in low-income and middle-income countries where tuberculosis is a grave public health problem. Growth in this double disease burden creates additional obstacles for tuberculosis care and prevention. We review how the evolution of evidence on the link between tuberculosis and diabetes has informed global policy on collaborative activities, and how practice is starting to change as a consequence. We conclude that coordinated planning and service delivery across communicable and non-communicable disease programmes is necessary, feasible, and creates synergies that will help to reduce the burden of both tuberculosis and diabetes.
authors.affiliation: Departments of Global TB Programme, World Health Organization, Geneva, Switzerland. Electronic address: lonnrothk@who.int.
authors.forename: Knut
authors.initials: K
authors.lastname: Lönnroth
authors.affiliation: Management of Non-communicable Diseases, World Health Organization, Geneva, Switzerland.
authors.forename: Gojka
authors.initials: G
authors.lastname: Roglic
authors.affiliation: The International Union Against TB and Lung Diseases, Paris, France.
authors.forename: Anthony D
authors.initials: AD
authors.lastname: Harries
mesh_terms: D018890:Chemoprevention / Q000379:methods*; D003920:Diabetes Mellitus / Q000453:epidemiology / Q000503:physiopathology / Q000517:prevention & control*; D055317:Evidence-Based Practice; D014943:Global Health; D006291:Health Policy; D006801:Humans; D011050:Policy Making; D017410:Practice Guidelines as Topic; D015995:Prevalence; D011379:Prognosis; D012307:Risk Factors; D014376:Tuberculosis / Q000453:epidemiology / Q000503:physiopathology / Q000517:prevention & control*