title: A case of cutaneous protothecosis mimics eczema.
abstract: We report a case of cutaneous protothecosis due to Prototheca wickerhamii in an immunocompetent man presented with a specific eczema-like lesions. Dermatological examination revealed erythematous plaques, dark red papules with some coalescence, and a few superficial ulcerations, covered with less scales on his right side chest and neck. Fungal culture, histopathological examination and molecular identification confirmed the organism. Antifungal susceptibility testing revealed strain sensitive to amphotericin B, Fluconazole, itraconazole and voriconazole. The patient was cured by oral itraconazole capsules and topical cream ketoconazole 2%.
authors.affiliation: Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, 200040, China, zhangqq8@163.com.
authors.forename: Qiangqiang
authors.initials: Q
authors.lastname: Zhang
authors.forename: Li
authors.initials: L
authors.lastname: Li
authors.forename: Kang
authors.initials: K
authors.lastname: Yuli
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhao
authors.forename: Junhao
authors.initials: J
authors.lastname: Zhu
authors.forename: Min
authors.initials: M
authors.lastname: Zhu
mesh_terms: D000369:Aged, 80 and over; D000935:Antifungal Agents / Q000627:therapeutic use*; D001483:Base Sequence; D018744:DNA, Plant / Q000235:genetics; D004359:Drug Therapy, Combination; D004485:Eczema / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D007239:Infections / Q000175:diagnosis* / Q000188:drug therapy*; D017964:Itraconazole / Q000627:therapeutic use; D007654:Ketoconazole / Q000627:therapeutic use; D008297:Male; D058889:Molecular Typing; D011525:Prototheca / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D017422:Sequence Analysis, DNA
chemical_list: D000935:Antifungal Agents; D018744:DNA, Plant; D017964:Itraconazole; D007654:Ketoconazole