title: Increased power of resting-state gamma oscillations in autism spectrum disorder detected by routine electroencephalography.
abstract: Experimental studies suggest that increased resting-state power of gamma oscillations is associated with autism spectrum disorder (ASD). To extend the clinical applicability of this finding, we retrospectively investigated routine electroencephalography (EEG) recordings of 19 patients with ASD and 19 age- and gender-matched controls. Relative resting-state condition gamma spectral power was variable, but on average significantly increased in children with ASD. This effect remained when excluding electrodes associated with myogenic gamma activity. These findings further indicate that increased resting-state gamma activity characterizes a subset of ASD and may also be detected by routine EEG as a clinically accessible and well-tolerated investigation.
authors.affiliation: Department of Pediatric Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands, E.vanDiessen-3@umcutrecht.nl.
authors.forename: Eric
authors.initials: E
authors.lastname: van Diessen
authors.forename: Joeky
authors.initials: J
authors.lastname: Senders
authors.forename: Floor E
authors.initials: FE
authors.lastname: Jansen
authors.forename: Maria
authors.initials: M
authors.lastname: Boersma
authors.forename: Hilgo
authors.initials: H
authors.lastname: Bruining
mesh_terms: D000293:Adolescent; D000067877:Autism Spectrum Disorder / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D065818:Gamma Rhythm / Q000502:physiology*; D006801:Humans; D008297:Male; D012189:Retrospective Studies