title: The leukemias: a half-century of discovery.
abstract: Studies of the leukemias in the laboratory and in the clinic have generated many new concepts and therapies that will undoubtedly continue to be rapidly applied to the other forms of systemic cancer, particularly the concept of narrowly targeted personalized therapy that has proven so effective in CML. It seems likely that other subtypes of leukemia will eventually approach the success achieved with APL, CML, and pediatric ALL.
authors.affiliation: MD Anderson Cancer Center, Houston, TX.
authors.forename: Emil J
authors.initials: EJ
authors.lastname: Freireich
authors.affiliation: Cancer Research Foundation of New York, New York, NY.
authors.forename: Peter H
authors.initials: PH
authors.lastname: Wiernik
authors.affiliation: Dana-Farber Cancer Institute, Boston, MA.
authors.forename: David P
authors.initials: DP
authors.lastname: Steensma
mesh_terms: D000970:Antineoplastic Agents / Q000266:history* / Q000627:therapeutic use; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D007938:Leukemia / Q000188:drug therapy / Q000266:history*; D011643:Publishing / Q000266:history / Q000706:statistics & numerical data; D015996:Survival Rate; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents