title: Plasticity of language pathways in patients with low-grade glioma: A diffusion tensor imaging study.
abstract: Knowledge of the plasticity of language pathways in patients with low-grade glioma is important for neurosurgeons to achieve maximum resection while preserving neurological function. The current study sought to investigate changes in the ventral language pathways in patients with low-grade glioma located in regions likely to affect the dorsal language pathways. The results revealed no significant difference in fractional anisotropy values in the arcuate fasciculus between groups or between hemispheres. However, fractional anisotropy and lateralization index values in the left inferior longitudinal fasciculus and lateralization index values in the left inferior fronto-occpital fasciculus were higher in patients than in healthy subjects. These results indicate plasticity of language pathways in patients with low-grade glioma. The ventral language pathways may perform more functions in patients than in healthy subjects. As such, it is important to protect the ventral language pathways intraoperatively.
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, Chinese PLA Postgraduate Medical School, Beijing 100853, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Zheng
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, Chinese PLA Postgraduate Medical School, Beijing 100853, China.
authors.forename: Xiaolei
authors.initials: X
authors.lastname: Chen
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, Chinese PLA Postgraduate Medical School, Beijing 100853, China.
authors.forename: Bainan
authors.initials: B
authors.lastname: Xu
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, Chinese PLA Postgraduate Medical School, Beijing 100853, China.
authors.forename: Jiashu
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, Chinese PLA Postgraduate Medical School, Beijing 100853, China.
authors.forename: Xueming
authors.initials: X
authors.lastname: Lv
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, Chinese PLA Postgraduate Medical School, Beijing 100853, China.
authors.forename: Jinjiang
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, Chinese PLA Postgraduate Medical School, Beijing 100853, China.
authors.forename: Fangye
authors.initials: F
authors.lastname: Li
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, Chinese PLA Postgraduate Medical School, Beijing 100853, China.
authors.forename: Shen
authors.initials: S
authors.lastname: Hu
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, Chinese PLA Postgraduate Medical School, Beijing 100853, China.
authors.forename: Ting
authors.initials: T
authors.lastname: Zhang
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, Chinese PLA Postgraduate Medical School, Beijing 100853, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Li
keywords: diffusion tensor imaging; dorsal language pathway; fractional anisotropy; glioma; grants-supported paper; language pathways; lateralization index; low-grade glioma; neural regeneration; neuroimaging; neuroregeneration; photographs-containing paper; plasticity; ventral language pathway