title: [Correlation between liver hardness testing results obtained by FibroTouch and FibroScan and liver pathological stage].
abstract: OBJECTIVE
  To evaluate the correlation of liver hardness testing
  
  
  RESULTS
  obtained by FibroTouch and FibroScan and the liver pathological stage.
  
  
  METHODS
  Seventy-five patients with chronic hepatitis B who presented to our clinic between January 2011 and April 2013 were examined with FibroTouch and FibroScan to evaluate the degree of liver fibrosis. Forty-six of those patients also underwent liver biopsy examination.
  
  
  RESULTS
  from technology-based testing and histopathological evaluation of the biopsy were compared by statistical analysis to determine the consistency of FibroTouch and FibroScan in regard to histological stage.
  
  
  RESULTS
  Analysis by paired t-test showed that the
  
  
  RESULTS
  from FibroTouch and FibroScan were not significantly different (t = -0.17, P =0.8616), and the correlation coefficient from Pearson's correlation analysis was 0.9949 (P less than 0.05), suggesting that the two technologies'
  
  
  RESULTS
  are correlated. Based on the histopathology
  
  
  RESULTS
  for liver fibrosis stage, the FibroTouch diagnosis of liver fibrosis more than or equal to S 1 had a receiver operating characteristic (ROC) area under the curve (AUC) of 0.889, diagnosis of liver fibrosis more than or equal to S2 had a ROC AUC of 0.941, diagnosis of liver fibrosis more than or equal to S3 had a ROC AUC of 0.908, and diagnosis of liver fibrosis more than or equal to S4 had a ROC AUC of 0.911.
  
  
  CONCLUSIONS
  Compared to FibroScan, FibroTouch has a better ability for detecting liver fibrosis and a better consistency with liver pathological stage determined by histopathological analysis.
authors.affiliation: Department of Infectious Diseases, China-Japan Freindship Hospital, Beijing 100029, China.
authors.forename: Lichao
authors.initials: L
authors.lastname: Yuan
authors.forename: Jinhua
authors.initials: J
authors.lastname: Shao
authors.forename: Meina
authors.initials: M
authors.lastname: Hao
authors.forename: Cheng
authors.initials: C
authors.lastname: Li
authors.forename: Guiping
authors.initials: G
authors.lastname: Wang
authors.forename: Tailing
authors.initials: T
authors.lastname: Wang
authors.forename: Jianwen
authors.initials: J
authors.lastname: Luo
authors.forename: Jing
authors.initials: J
authors.lastname: Bai
authors.forename: Anlin
authors.initials: A
authors.lastname: Ma
mesh_terms: D000328:Adult; D000368:Aged; D019540:Area Under Curve; D001706:Biopsy; D016022:Case-Control Studies; D054459:Elasticity Imaging Techniques / Q000295:instrumentation*; D005260:Female; D019694:Hepatitis B, Chronic / Q000473:pathology*; D006801:Humans; D008099:Liver / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D055815:Young Adult