title: Surgical treatment of peri-implantitis using a bone substitute with or without a resorbable membrane: a 5-year follow-up.
abstract: OBJECTIVE
  To compare two regenerative surgical treatments for peri-implantitis over 5 years.
  
  
  METHODS
  Twenty-five individuals with peri-implantitis remained at study endpoint. They were treated with a bone substitute and a resorbable membrane (13 individuals with 23 implants) [Group 1], or with bone substitute alone (12 individuals with 22 implants) [Group 2]. All study individuals were kept on a strict maintenance programme every third month.
  
  
  RESULTS
  Five-year follow-up demonstrated clinical and radiographic improvements in both groups. No implants were lost due to progression of peri-implantitis. Probing depths were reduced by 3.0 ± 2.4 mm in Group 1, and 3.3 ± 2.09 mm in Group 2 (NS). In both groups, radiographic evidence of bone gain was significant (p < 0.001). At year 5, the average defect fill was 1.3 mm (SD ± 1.4 mm) in Group 1 and 1.1 mm (SD ± 1.2 mm) in Group 2 (mean diff; 0.4 95% CI -0.3, 1.2, p = 0.24). Bleeding on probing decreased in both groups. Baseline and year 5 plaque scores did not differ between groups and was reduced from 50% to 15%.
  
  
  CONCLUSIONS
  Both procedures resulted in stable conditions. Additional use of a membrane does not improve the outcome.
authors.affiliation: Department of Periodontology, Public Dental Health Service, Kristianstad, Sweden; Department of Oral Sciences, Kristianstad University, Kristianstad, Sweden.
authors.forename: Ann-Marie
authors.initials: AM
authors.lastname: Roos-Jansåker
authors.forename: Gösta Rutger
authors.initials: GR
authors.lastname: Persson
authors.forename: Christel
authors.initials: C
authors.lastname: Lindahl
authors.forename: Stefan
authors.initials: S
authors.lastname: Renvert
mesh_terms: D020341:Absorbable Implants; D000368:Aged; D016301:Alveolar Bone Loss / Q000601:surgery; D018786:Bone Substitutes / Q000627:therapeutic use*; D003646:Debridement / Q000379:methods; D003774:Dental Plaque Index; D004202:Disinfectants / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D005889:Gingival Recession / Q000601:surgery; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods*; D006801:Humans; D006861:Hydrogen Peroxide / Q000627:therapeutic use; D008137:Longitudinal Studies; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D057873:Peri-Implantitis / Q000000981:diagnostic imaging / Q000601:surgery*; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000601:surgery; D011859:Radiography; D016037:Single-Blind Method; D013524:Surgical Flaps / Q000601:surgery; D016896:Treatment Outcome
chemical_list: C483718:Algipore; D018786:Bone Substitutes; D004202:Disinfectants; D008567:Membranes, Artificial; D006861:Hydrogen Peroxide
keywords: bone substitute; defect fill; peri-implantitis; resorbable membrane; surgery