title: Xpert(®) MTB/RIF assay for tuberculosis diagnosis: evaluation in an Indian setting.
abstract: The present study was conducted to evaluate the performance of the Xpert(®) MTB/RIF assay and compare Xpert results with solid and MGIT 960 liquid culture system. A total of 134 patients who had failed the Category I or II regimen were recruited for evaluation. Xpert correctly identified all Mycobacterium tuberculosis isolates. The sensitivity and specificity of the Xpert assay for the detection of rifampicin resistance was respectively 98.2% and 97.0% when compared with MGIT 960 results.
authors.affiliation: Department of Microbiology, Lala Ram Sarup Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
authors.forename: V P
authors.initials: VP
authors.lastname: Myneedu
authors.affiliation: Department of Microbiology, Lala Ram Sarup Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
authors.forename: D
authors.initials: D
authors.lastname: Behera
authors.affiliation: Department of Microbiology, Lala Ram Sarup Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
authors.forename: A K
authors.initials: AK
authors.lastname: Verma
authors.affiliation: Department of Microbiology, Lala Ram Sarup Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
authors.forename: M
authors.initials: M
authors.lastname: Bhalla
authors.affiliation: Department of Microbiology, Lala Ram Sarup Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
authors.forename: N
authors.initials: N
authors.lastname: Singh
authors.affiliation: Department of Microbiology, Lala Ram Sarup Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
authors.forename: J
authors.initials: J
authors.lastname: Arora
authors.affiliation: Department of Microbiology, Lala Ram Sarup Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
authors.forename: R
authors.initials: R
authors.lastname: Singhal
authors.affiliation: Department of Microbiology, Lala Ram Sarup Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
authors.forename: M
authors.initials: M
authors.lastname: Mathur
authors.affiliation: Department of Microbiology, Lala Ram Sarup Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
authors.forename: P
authors.initials: P
authors.lastname: Lal
authors.affiliation: Department of Microbiology, Lala Ram Sarup Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
authors.forename: R
authors.initials: R
authors.lastname: Sarin
mesh_terms: D000904:Antibiotics, Antitubercular / Q000494:pharmacology*; D001431:Bacteriological Techniques / Q000379:methods; D024881:Drug Resistance, Bacterial; D006801:Humans; D007194:India; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000302:isolation & purification; D012293:Rifampin / Q000494:pharmacology*; D012680:Sensitivity and Specificity; D014376:Tuberculosis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000904:Antibiotics, Antitubercular; D012293:Rifampin