title: Drug eluting balloon: a multipurpose tool for coronary revascularization with optimal long-term follow-up results.
abstract: OBJECTIVE
  This study aimed to evaluate safety and efficacy of drug-coated balloon (DCB) at long-term follow-up; a large series of real-life patients underwent revascularization with DCB for a wide spectrum of clinical and angiographic situations.
  
  
  RESULTS
  One hundred ten patients underwent percutaneous revascularization using paclitaxel eluting balloon (Sequent Please, Braun, Germany). End-points were major adverse cardiac events (MACE; all-cause death, myocardial infarction [MI], target vessel revascularisation [TVR], and vessel thrombosis). DCB were used for stable angina (58%), unstable angina/nonST elevation MI (31%) and ST elevation MI (11%). DCB were used for in-stent restenosis (61%), small vessel disease (25%), with bare metal stent (BMS) to avoid long dual antiplatelet therapy (10%) or for impossibility to place a stent (4%). Cumulative MACE at follow-up (median 23 months, IQR 13-32) was 12.7%, with 8.2% all-cause death (1 fatal MI), 4.5% TVR, 3.6% TLR, and no vessel thrombosis. Three of four TLRs occurred in patients who received DEB for DES restenosis.
  
  
  CONCLUSIONS
  DCB are a very effective tool for a variety of clinical and angiographic situations. DCB use seems to be affected by a low rate of complications and adequate results at long-term follow-up.
authors.affiliation: Division of Interventional Cardiology, Fondazione G. Monasterio CNR-Regione Toscana, Pisa-Massa, Italy.
authors.forename: Luigi Emilio
authors.initials: LE
authors.lastname: Pastormerlo
authors.forename: Marco
authors.initials: M
authors.lastname: Ciardetti
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Trianni
authors.forename: Marcello
authors.initials: M
authors.lastname: Ravani
authors.forename: Mathis
authors.initials: M
authors.lastname: Shlueter
authors.forename: Marco
authors.initials: M
authors.lastname: Vaghetti
authors.forename: Michele
authors.initials: M
authors.lastname: Coceani
authors.forename: Antonio
authors.initials: A
authors.lastname: Rizza
authors.forename: Sergio
authors.initials: S
authors.lastname: Berti
authors.forename: Cataldo
authors.initials: C
authors.lastname: Palmieri
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D060050:Angina, Stable / Q000628:therapy; D000789:Angina, Unstable / Q000628:therapy; D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation*; D023903:Coronary Restenosis / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000628:therapy; D017239:Paclitaxel / Q000008:administration & dosage; D012042:Registries
chemical_list: D017239:Paclitaxel