title: Electroencephalographic Changes of Brain Oscillatory Activity After Upper Limb Somatic Sensation Training in a Patient With Somatosensory Deficit After Stroke.
abstract: The development of an innovative functional assessment procedure based on the combination of electroencephalography (EEG) and robot-assisted upper limb devices may provide new insights into the dynamics of cortical reorganization promoted by rehabilitation. The aim of this study was to evaluate changes in event-related synchronization/desynchronization (ERS/ERD) in alpha and beta bands in a patient with pure sensory stroke who underwent a specific rehabilitation program for somatic sensation recovery. A 49-year-old, right-handed woman (time since stroke, 12 months) with severe upper limb somatic sensation deficits was tested using validated clinical scales and a standardized video-EEG system combined with the Bi-Manu-Track robot-assisted arm trainer protocol. The patient underwent a 3-month home-based rehabilitation program for promoting upper limb recovery (1 hour a day for 5 days a week). She was tested before treatment, at 1-month, and at 3-month during treatment. Results showed progressive recovery of upper limb function over time. These effects were associated with specific changes in the modulation of alpha and beta event-related synchronization/desynchronization. This unique study provides new perspectives for the assessment of functional deficits and changes in cortical activity promoted by rehabilitation in poststroke patients.
authors.affiliation: Neuromotor and Cognitive Rehabilitation Research Centre (CRRNC), USO Neurological Rehabilitation, AOUI of Verona, Verona, Italy Department of Neurological and Movement Sciences, University of Verona, Verona, Italy.
authors.forename: Marialuisa
authors.initials: M
authors.lastname: Gandolfi
authors.affiliation: Department of Neurophysiology, IRCCS Foundation San Camillo Hospital, Venice, Italy.
authors.forename: Emanuela
authors.initials: E
authors.lastname: Formaggio
authors.affiliation: Neuromotor and Cognitive Rehabilitation Research Centre (CRRNC), USO Neurological Rehabilitation, AOUI of Verona, Verona, Italy Department of Neurological and Movement Sciences, University of Verona, Verona, Italy.
authors.forename: Christian
authors.initials: C
authors.lastname: Geroin
authors.affiliation: Department of Neurological and Movement Sciences, University of Verona, Verona, Italy.
authors.forename: Silvia Francesca
authors.initials: SF
authors.lastname: Storti
authors.affiliation: Department of Neurological and Movement Sciences, University of Verona, Verona, Italy.
authors.forename: Ilaria
authors.initials: I
authors.lastname: Boscolo Galazzo
authors.affiliation: Department of Neurological Rehabilitation, Private Hospital Villa Melitta, Bolzano, Italy.
authors.forename: Andreas
authors.initials: A
authors.lastname: Waldner
authors.affiliation: Department of Neurological and Movement Sciences, University of Verona, Verona, Italy Department of Neurophysiology, IRCCS Foundation San Camillo Hospital, Venice, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Manganotti
authors.affiliation: Neuromotor and Cognitive Rehabilitation Research Centre (CRRNC), USO Neurological Rehabilitation, AOUI of Verona, Verona, Italy Department of Neurological and Movement Sciences, University of Verona, Verona, Italy nicola.smania@univr.it.
authors.forename: Nicola
authors.initials: N
authors.lastname: Smania
mesh_terms: D000513:Alpha Rhythm / Q000502:physiology; D001611:Beta Rhythm / Q000502:physiology; D003344:Cortical Synchronization; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008875:Middle Aged; D011597:Psychomotor Performance / Q000502:physiology; D012371:Robotics; D020521:Stroke / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome; D034941:Upper Extremity / Q000503:physiopathology*
keywords: cortical desynchronization; cortical synchronization; passive movement therapy; plasticity; rehabilitation