title: Trends, productivity losses, and associated medical conditions among toxoplasmosis deaths in the United States, 2000-2010.
abstract: Few studies have quantified toxoplasmosis mortality, associated medical conditions, and productivity losses in the United States. We examined national multiple cause of death data and estimated productivity losses caused by toxoplasmosis during 2000-2010. A matched case-control analysis examined associations between comorbid medical conditions and toxoplasmosis deaths. In total, 789 toxoplasmosis deaths were identified during the 11-year study period. Blacks and Hispanics had the highest toxoplasmosis mortality compared with whites. Several medical conditions were associated with toxoplasmosis deaths, including human immunodeficiency virus (HIV), lymphoma, leukemia, and connective tissue disorders. The number of toxoplasmosis deaths with an HIV codiagnosis declined from 2000 to 2010; the numbers without such a codiagnosis remained static. Cumulative disease-related productivity losses for the 11-year period were nearly $815 million. Although toxoplasmosis mortality has declined in the last decade, the infection remains costly and is an important cause of preventable death among non-HIV subgroups.
authors.affiliation: Division of Chronic Disease and Injury Prevention, Los Angeles County Department of Public Health, Los Angeles, California; Department of Epidemiology, Jonathan and Karin Fielding School of Public Health, University of California, Los Angeles, California pcummings@ph.lacounty.gov.
authors.forename: Patricia L
authors.initials: PL
authors.lastname: Cummings
authors.affiliation: Division of Chronic Disease and Injury Prevention, Los Angeles County Department of Public Health, Los Angeles, California; Department of Epidemiology, Jonathan and Karin Fielding School of Public Health, University of California, Los Angeles, California.
authors.forename: Tony
authors.initials: T
authors.lastname: Kuo
authors.affiliation: Division of Chronic Disease and Injury Prevention, Los Angeles County Department of Public Health, Los Angeles, California; Department of Epidemiology, Jonathan and Karin Fielding School of Public Health, University of California, Los Angeles, California.
authors.forename: Marjan
authors.initials: M
authors.lastname: Javanbakht
authors.affiliation: Division of Chronic Disease and Injury Prevention, Los Angeles County Department of Public Health, Los Angeles, California; Department of Epidemiology, Jonathan and Karin Fielding School of Public Health, University of California, Los Angeles, California.
authors.forename: Frank
authors.initials: F
authors.lastname: Sorvillo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044383:Black People; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D003240:Connective Tissue Diseases / Q000453:epidemiology; D005260:Female; D015658:HIV Infections / Q000453:epidemiology; D006630:Hispanic or Latino; D006801:Humans; D007223:Infant; D007938:Leukemia / Q000453:epidemiology; D008223:Lymphoma / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D014123:Toxoplasmosis / Q000191:economics* / Q000453:epidemiology / Q000401:mortality*; D014481:United States / Q000453:epidemiology; D044465:White People; D055815:Young Adult; D001741:Black or African American