title: Polyethylene glycol-based ultrasound-assisted extraction of magnolol and honokiol from Cortex Magnoliae Officinalis.
abstract: In this study, a kind of green solvent named polyethylene glycol (PEG) was developed for the ultrasound-assisted extraction (UAE) of magnolol and honokiol from Cortex Magnoliae Officinalis. The effects of PEG molecular weight, PEG concentration, sample size, pH, ultrasonic power and extraction time on the extraction of magnolol and honokiol were investigated to optimise the extraction conditions. Under the optimal extraction conditions, the PEG-based UAE supplied higher extraction efficiencies of magnolol and honokiol than the ethanol-based UAE and traditional ethanol-reflux extraction. Furthermore, the correlation coefficient (R(2)), repeatability (relative standard deviation, n = 6) and recovery confirmed the validation of the proposed extraction method, which were 0.9993-0.9996, 3.1-4.6% and 92.3-106.8%, respectively.
authors.affiliation: a Department of Food Science and Nutrition , School of Hotel Management, University of Jinan , No. 13, Shungeng Road, Jinan , Shandong 250002 , P.R. China.
authors.forename: Lei
authors.initials: L
authors.lastname: He
authors.forename: Tao
authors.initials: T
authors.lastname: Fan
authors.forename: Jianguo
authors.initials: J
authors.lastname: Hu
authors.forename: Lijin
authors.initials: L
authors.lastname: Zhang
mesh_terms: D001713:Biphenyl Compounds / Q000737:chemistry / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification*; D031566:Magnolia / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*; D014465:Ultrasonics; D000498:Allyl Compounds; D010636:Phenols
chemical_list: D001713:Biphenyl Compounds; D004365:Drugs, Chinese Herbal; D017705:Lignans; D011092:Polyethylene Glycols; C005498:magnolol; C005499:honokiol; D000498:Allyl Compounds; D010636:Phenols
keywords: Cortex Magnoliae Officinalis; PEG; honokiol; magnolol; ultrasound-assisted extraction