title: Antiplaque and antigingivitis efficacy of triphala and chlorhexidine mouthrinse among schoolchildren - a cross-over, double-blind, randomised controlled trial.
abstract: OBJECTIVE
  To evaluate and compare the effect of triphala extract mouthrinse and chlorhexidine on dental plaque and gingivitis.
  
  
  METHODS
  In this double blind, crossover study, 120 qualifying boarding-school students aged 13-16 years were randomised into three groups: 10% triphala, 0.2% chlorhexidine and negative control. The study was conducted in 3 phases of 1-month duration each and a washout period of 15 days. During the experimental period, subjects rinsed with the allocated mouthrinse once daily for 30 s under supervision. The plaque and gingival status was assessed using the Turesky modification of the Quigley and Hein plaque index (QHI) and the gingival index (Löe and Silness) at baseline and at the end of each phase. The results were tested for significance at P < 0.05.
  
  
  RESULTS
  Triphala and chlorhexidine yielded a significant reduction in plaque and gingival index scores as compared to negative control (P < 0.001). No significant difference was found between the scores obtained with triphala and chlorhexidine mouthwashes.
  
  
  CONCLUSIONS
  The antiplaque and antigingivitis activity of triphala closely parallels that of chlorhexidine.
authors.forename: Swati H
authors.initials: SH
authors.lastname: Chainani
authors.forename: Sunitha
authors.initials: S
authors.lastname: Siddana
authors.forename: Cvk
authors.initials: C
authors.lastname: Reddy
authors.forename: Thippeswamy H
authors.initials: TH
authors.lastname: Manjunathappa
authors.forename: Maurya
authors.initials: M
authors.lastname: Manjunath
authors.forename: Sushma
authors.initials: S
authors.lastname: Rudraswamy
mesh_terms: D000293:Adolescent; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D016022:Case-Control Studies; D002710:Chlorhexidine / Q000627:therapeutic use*; D018592:Cross-Over Studies; D003773:Dental Plaque / Q000517:prevention & control*; D003774:Dental Plaque Index; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D005891:Gingivitis / Q000517:prevention & control*; D006801:Humans; D008297:Male; D009067:Mouthwashes / Q000627:therapeutic use*; D010512:Periodontal Index; D029842:Phyllanthus emblica; D008517:Phytotherapy / Q000379:methods; D010936:Plant Extracts / Q000627:therapeutic use*; D029766:Terminalia; D016896:Treatment Outcome
chemical_list: D000891:Anti-Infective Agents, Local; D009067:Mouthwashes; D010936:Plant Extracts; C520904:triphala; D002710:Chlorhexidine