title: A new tonometric device for radial augmentation index and subendocardial viability ratio: potential use in health screening.
abstract: Augmentation index (AIx) and subendocardial viability ratio (SEVR) are widely accepted indices of wave reflection and myocardial oxygen demand relative to supply. This study aimed to validate a new tonometric device (IIM-2010A) for obtaining AIx and SEVR from radial artery. A total of 68 outpatients (32 men and 36 women) aged 20 to 76 years (44.7±16.6 years) recruited from a health screening center participated in the study. AIx was obtained from radial pressure using the HEM-9000AI and IIM-2010A devices, while SEVR was measured from carotid pressure with the tonometric method and from radial pressure by the IIM-2010A device. In a subgroup of 24 patients, the measurements of AIx and SEVR were repeated after an interval of 10 minutes. The correlation of radial AIx between the IIM-2010A and HEM-9000AI devices was highly significant (r=0.956, P<.01). Radial SEVR determined from IIM-2010A was also highly related to carotid SEVR (r=0.864, P<.01), although the value was about 13.1% lower. There was no statistically significant difference between the repeated measurements of both indices. The lower coefficient of variation (2.9% vs 4.3% for AIx, 3.3% vs 4.1% for SEVR) and higher intraclass correlation coefficient (0.96 vs 0.91 for AIx, 0.93 vs 0.86 for SEVR) of IIM-2010A confirmed better short-term reproducibility, compared with the HEM-9000AI device and carotid tonometry. The new tonometric device IIM-2010A is effective and reproducible in calculating radial AIx and SEVR and has potential use in health screening.
authors.affiliation: Department of Automation, University of Science and Technology of China, Hefei, China; Research Center for Information Technology of Sports and Health, Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei, China.
authors.forename: Jing-Zhi
authors.initials: JZ
authors.lastname: Wang
authors.forename: Yong-Liang
authors.initials: YL
authors.lastname: Zhang
authors.forename: Fu-Song
authors.initials: FS
authors.lastname: Hu
authors.forename: Zi-Jun
authors.initials: ZJ
authors.lastname: He
authors.forename: Xian-Jun
authors.initials: XJ
authors.lastname: Yang
authors.forename: Zu-Chang
authors.initials: ZC
authors.lastname: Ma
authors.forename: Yi-Ning
authors.initials: YN
authors.lastname: Sun
mesh_terms: D000328:Adult; D000368:Aged; D062186:Arterial Pressure / Q000502:physiology*; D002339:Carotid Arteries / Q000503:physiopathology; D004699:Endocardium / Q000503:physiopathology*; D004867:Equipment Design; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry / Q000295:instrumentation*; D008403:Mass Screening / Q000295:instrumentation*; D008875:Middle Aged; D010101:Oxygen Consumption / Q000502:physiology*; D063177:Pulse Wave Analysis / Q000295:instrumentation*; D017534:Radial Artery / Q000503:physiopathology; D012680:Sensitivity and Specificity; D013223:Statistics as Topic; D014022:Tissue Survival / Q000502:physiology*; D059289:Vascular Stiffness / Q000502:physiology*; D055815:Young Adult