title: A multi-heme flavoenzyme as a solar conversion catalyst.
abstract: The enzyme flavocytochrome c3 (fcc3), which catalyzes hydrogenation across a C═C double bond (fumarate to succinate), is used to carry out the fuel-forming reaction in an artificial photosynthesis system. When immobilized on dye-sensitized TiO2 nanoparticles, fcc3 catalyzes visible-light-driven succinate production in aqueous suspension. Solar-to-chemical conversion using neutral water as the oxidant is achieved with a photoelectrochemical cell comprising an fcc3-modified indium tin oxide cathode linked to a cobalt phosphate-modified BiVO4 photoanode. The results reinforce new directions in the area of artificial photosynthesis, in particular for solar-energy-driven synthesis of organic chemicals and commodities, moving away from simple fuels as target molecules.
authors.affiliation: Inorganic Chemistry Laboratory, Department of Chemistry, University of Oxford , South Parks Road, Oxford OX1 3QR, United Kingdom.
authors.forename: Andreas
authors.initials: A
authors.lastname: Bachmeier
authors.forename: Bonnie J
authors.initials: BJ
authors.lastname: Murphy
authors.forename: Fraser A
authors.initials: FA
authors.lastname: Armstrong
mesh_terms: D002384:Catalysis; D004396:Coloring Agents / Q000737:chemistry*; D003574:Cytochrome c Group / Q000378:metabolism*; D004566:Electrodes; D004800:Enzymes, Immobilized / Q000378:metabolism*; D008027:Light; D053758:Nanoparticles / Q000737:chemistry*; D010788:Photosynthesis; D020614:Shewanella putrefaciens / Q000201:enzymology*; D012993:Solar Energy; D013385:Succinate Dehydrogenase / Q000378:metabolism*; D019802:Succinic Acid / Q000378:metabolism; D017971:Tin Compounds / Q000737:chemistry; D014025:Titanium / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D004396:Coloring Agents; D003574:Cytochrome c Group; D004800:Enzymes, Immobilized; D017971:Tin Compounds; D014867:Water; C009495:titanium dioxide; C109984:indium tin oxide; D019802:Succinic Acid; D014025:Titanium; C112400:flavocytochrome c3; D013385:Succinate Dehydrogenase