title: Post-operative refractory cystoid macular edema in a vitrectomized eye treated with slow-release dexamethasone implant (Ozurdex).
abstract: BACKGROUND
  The use of a slow-release dexamethasone implant (Ozurdex) for the treatment of post-operative macular edema (ME) in a vitrectomized eye has never been used before. We herein report a case of a 70-year-old woman with post-vitrectomy ME refractory to topical, sub-tenon's and intravitreal steroid administration that responded well to the implantation of a slow-release dexamethasone implant (Ozurdex) in a previously vitrectomized eye.
  
  
  METHODS
  Interventional case presentation.
  
  
  RESULTS
  One week post-implantation, the central retinal thickness was reduced to 383 μm from 640 μm and the best corrected visual acuity (BCVA) improved to 6/36 from counting fingers (CF). At six months' follow-up visit, the improvement of the ME was sustained as indicated by the optical coherence tomography (OCT) measurements and the BCVA remained stable. No serious topical or systemic adverse events were observed from the implantation of Ozurdex in the vitrectomized eye.
  
  
  CONCLUSIONS
  The use of Ozurdex in our case resulted in rapid improvement of the post-operative resistant ME. To the best of our knowledge, this is the first report in the literature demonstrating the use of the slow-release dexamethasone implant (Ozurdex) to treat post-operative ME in a vitrectomized eye.
authors.affiliation: Department of Ophthalmology, University of Athens , Athens , Greece and.
authors.forename: Ilias
authors.initials: I
authors.lastname: Georgalas
authors.forename: Petros
authors.initials: P
authors.lastname: Petrou
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Papakonstantinou
authors.forename: Vagelis
authors.initials: V
authors.lastname: Droumouchtsis
authors.forename: Ioannis
authors.initials: I
authors.lastname: Tservakis
mesh_terms: D000368:Aged; D003907:Dexamethasone / Q000008:administration & dosage*; D004343:Drug Implants; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008269:Macular Edema / Q000188:drug therapy* / Q000503:physiopathology / Q000601:surgery*; D011183:Postoperative Complications; D014792:Visual Acuity; D014821:Vitrectomy
chemical_list: D004343:Drug Implants; D003907:Dexamethasone
keywords: Dexamethasone implant; Ozurdex; post-operative macular edema; vitrectomy