title: The neural network underlying incentive-based learning: implications for interpreting circuit disruptions in psychiatric disorders.
abstract: Coupling stimuli and actions with positive or negative outcomes facilitates the selection of appropriate actions. Several brain regions are involved in the development of goal-directed behaviors and habit formation during incentive-based learning. This Review focuses on higher cognitive control of decision making and the cortical and subcortical structures and connections that attribute value to stimuli, associate that value with choices, and select an action plan. Delineating the connectivity between these areas is fundamental for understanding how brain regions work together to evaluate stimuli, develop actions plans, and modify behavior, as well as for elucidating the pathophysiology of psychiatric diseases.
authors.affiliation: Department of Pharmacology and Physiology, University of Rochester School of Medicine, Rochester, NY 14642, USA. Electronic address: suzanne_haber@urmc.rochester.edu.
authors.forename: Suzanne N
authors.initials: SN
authors.lastname: Haber
authors.affiliation: FMRIB Centre, University of Oxford, Oxford, OX3 9DU, UK; Wellcome Trust Centre for Neuroimaging, University College London, London, WC1N 3BG, UK.
authors.forename: Timothy E J
authors.initials: TE
authors.lastname: Behrens
mesh_terms: D001921:Brain / Q000473:pathology*; D001931:Brain Mapping; D006801:Humans; D007859:Learning Disabilities / Q000473:pathology*; D009042:Motivation / Q000502:physiology*; D009415:Nerve Net / Q000473:pathology; D009434:Neural Pathways / Q000473:pathology*