title: A base-catalyzed cycloisomerization of 5-cyano-pentyne derivatives: an efficient synthesis of 3-cyano-4,5-dihydro-1H-pyrroles.
abstract: A base-catalyzed cycloisomerization of 5-cyano-pentyne bearing a terminal alkyne group has been developed under metal-free conditions. This reaction involves a tandem process providing efficient access to 3-cyano-4,5-dihydro-1H-pyrroles in good to excellent yields in an atom-economic manner with 1,3-cyano migration as the key transformation.
authors.affiliation: Department of Chemistry, Northeast Normal University, Changchun, 130024, China. zhaoyl351@nenu.edu.cn liuqun@nenu.edu.cn.
authors.forename: Jia
authors.initials: J
authors.lastname: Meng
authors.forename: Yi-Jin
authors.initials: YJ
authors.lastname: Li
authors.forename: Yu-Long
authors.initials: YL
authors.lastname: Zhao
authors.forename: Xiu-Bin
authors.initials: XB
authors.lastname: Bu
authors.forename: Qun
authors.initials: Q
authors.lastname: Liu