title: Antimicrobial activity of some essential oils against oral multidrug-resistant Enterococcus faecalis in both planktonic and biofilm state.
abstract: OBJECTIVE
  To evaluate some essential oils in treatment of intractable oral infections, principally caused by biofilm of multidrug-resistant Enterococcus faecalis (E. faecalis), such as persistent endodontic infections in which their treatment exhibits a real challenge for dentists.
  
  
  METHODS
  Ten chemically analyzed essential oils by gas chromatography-mass spectrometry were evaluated for antimicrobial activity against sensitive and resistant clinical strains of E. faecalis in both planktonic and biofilm state using two methods, disk diffusion and broth micro-dilution.
  
  
  RESULTS
  Studied essential oils showed a good antimicrobial activity and high ability in E. faecalis biofilm eradication, whether for sensitive or multidrug-resistant strains, especially those of Origanum glandulosum and Thymbra capitata with interesting minimum inhibitory concentration, biofilm inhibitory concentration, and biofilm eradication concentration values which doesn't exceed 0.063%, 0.75%, and 1.5%, respectively.
  
  
  CONCLUSIONS
  Findings of this study indicate that essential oils extracted from aromatic plants can be used in treatment of intractable oral infections, especially caused by biofilm of multidrug-resistant E. faecalis.
authors.affiliation: Laboratory of Applied Microbiology in Food, Biomedical and Environment (LAMAABE), Aboubekr Belkaïd University, PO Box 119, 13000 Tlemcen, Algeria.
authors.forename: Fethi
authors.initials: F
authors.lastname: Benbelaïd
authors.affiliation: Laboratory of Applied Microbiology in Food, Biomedical and Environment (LAMAABE), Aboubekr Belkaïd University, PO Box 119, 13000 Tlemcen, Algeria.
authors.forename: Abdelmounaïm
authors.initials: A
authors.lastname: Khadir
authors.affiliation: Laboratory of Applied Microbiology in Food, Biomedical and Environment (LAMAABE), Aboubekr Belkaïd University, PO Box 119, 13000 Tlemcen, Algeria.
authors.forename: Mohamed Amine
authors.initials: MA
authors.lastname: Abdoune
authors.affiliation: Laboratory of Applied Microbiology in Food, Biomedical and Environment (LAMAABE), Aboubekr Belkaïd University, PO Box 119, 13000 Tlemcen, Algeria.
authors.forename: Mourad
authors.initials: M
authors.lastname: Bendahou
authors.affiliation: Laboratory of Natural Products Chemistry, University of Corsica, UMR CNRS 6134, Campus Grimaldi, BP 52, 20250 Corte, France.
authors.forename: Alain
authors.initials: A
authors.lastname: Muselli
authors.affiliation: Laboratory of Natural Products Chemistry, University of Corsica, UMR CNRS 6134, Campus Grimaldi, BP 52, 20250 Corte, France.
authors.forename: Jean
authors.initials: J
authors.lastname: Costa
keywords: Bacterial infections; Biofilm; Enterococcus faecalis; Essential oils; Multidrug-resistance