title: Effect of an ACE inhibitor on allergic reaction to a bee sting.
abstract: An 83-year-old man being treated with combination product containing perindopril and indapamide had a systemic reaction after being stung by a bee. An angiotensin-converting enzyme inhibitor may significantly increase the severity of allergic reactions after being stung by bees, ants, or wasps. Clinicians should be aware of the potential for this phenomenon if assisting people who have been stung.
authors.affiliation: C/-Pharmacy Department, Repatriation General Hospital, Daw Park, South Australia, Australia.
authors.forename: Christopher P
authors.initials: CP
authors.lastname: Alderman
mesh_terms: D000369:Aged, 80 and over; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects*; D000818:Animals; D001516:Bees; D004232:Diuretics / Q000009:adverse effects; D004338:Drug Combinations; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000139:chemically induced* / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D007190:Indapamide / Q000009:adverse effects; D007299:Insect Bites and Stings / Q000276:immunology / Q000503:physiopathology*; D008297:Male; D020913:Perindopril / Q000009:adverse effects; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D004232:Diuretics; D004338:Drug Combinations; D007190:Indapamide; D020913:Perindopril