title: Neostigmine and pulmonary oedema.
abstract: A 1-year-old child with no pre-existing cardiac or respiratory disease developed frank pulmonary oedema after administration of a neostigmine-glycopyrrolate mixture to reverse neuromuscular blockade during general anaesthesia. Possible cardiac and extra-cardiac factors that could cause pulmonary oedema in this child were ruled out by appropriate investigations. As the pulmonary oedema manifested shortly after administration of the neostigmine-glycopyrrolate mixture, we concluded that neostigmine was the most probable cause. This article briefly reports the occurrence of events and successful management of perioperative pulmonary oedema.
authors.affiliation: Department of Anaesthesia and Critical Care, Mahatma Gandhi Medical College & Research Institute, Pondicherry, India.
authors.forename: Amrutha Bindu
authors.initials: AB
authors.lastname: Nagella
authors.affiliation: Department of Anaesthesia & Critical Care, Al-Ameen Medical College, Bijapur, Karnataka, India.
authors.forename: Mubina Begum
authors.initials: MB
authors.lastname: Bijapur
authors.affiliation: Bangalore Medical College & Research Institute, Bangalore, Karnataka, India.
authors.forename: Shreyavathi
authors.initials: S
authors.lastname: Shreyavathi
authors.affiliation: Bangalore Medical College & Research Institute, Bangalore, Karnataka, India.
authors.forename: Raghavendra R S
authors.initials: RR
authors.lastname: Rao
mesh_terms: D000768:Anesthesia, General; D002800:Cholinesterase Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D006024:Glycopyrrolate / Q000008:administration & dosage; D006801:Humans; D007223:Infant; D009388:Neostigmine / Q000009:adverse effects* / Q000627:therapeutic use; D011183:Postoperative Complications / Q000188:drug therapy; D011654:Pulmonary Edema / Q000139:chemically induced*
chemical_list: D002800:Cholinesterase Inhibitors; D009388:Neostigmine; D006024:Glycopyrrolate