title: Is prophylactic psychiatry around the corner? combating adolescent oxidative stress for adult psychosis and schizophrenia.
abstract: Early detection and intervention are key principles in clinical medicine and psychiatry. In this issue of Neuron, Cabungcal et al. (2014) demonstrate that prophylactic treatment with antioxidants in adolescence prevents adult deficits in a rat model relevant to schizophrenia.
authors.affiliation: Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address: asawa1@jhmi.edu.
authors.forename: Akira
authors.initials: A
authors.lastname: Sawa
authors.affiliation: Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.
authors.forename: Larry J
authors.initials: LJ
authors.lastname: Seidman
mesh_terms: D000111:Acetylcysteine / Q000008:administration & dosage*; D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage*; D005260:Female; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D011247:Pregnancy; D012559:Schizophrenia / Q000503:physiopathology* / Q000517:prevention & control*
chemical_list: D000975:Antioxidants; D000111:Acetylcysteine