title: Prevalence and clinicopathological comparison of kerotocystic odontogenic tumor and orthokeratinized odontogenic cyst in South Indian sample population: A retrospective study over 13 years.
abstract: OBJECTIVE
  The purpose of this study is to determine the prevalence of keratocystic odontogenic tumor (KCOT) and orthokeratinized odontogenic cyst (OOC), to identify their clinicopathological features among the patients by studying the biopsy specimens obtained from the archives of the Department of Oral and Maxillofacial Pathology, College of Dental Sciences, Davangere, Karnataka, India during the period of 2001-2013. Data for this study is retrieved from the case records of the patients fitting the histological classification of the World Health Organization (2005). The following clinical variables, namely age, gender, anatomical location, and histological features are analyzed.
  
  
  RESULTS
  Of the 3026 biopsy reports (100%) present in the archives, we had 31 cases (1.02%) of KCOT, 11 cases (0.36%) of OOC and a combination of para and orthokeratinized lining epithelium made 1 case (0.033%). The most frequent clinical manifestation was asymptomatic followed by the combination of pain and swelling. The male: female ratio was 1.4:1 with a mean age of 30 years in KCOT, while 2.7:1 with a mean age of 29.1 years in OOC. Posterior molar-ramus region was most commonly involved in both KCOT and OOC.
  
  
  CONCLUSIONS
  Due to aggressiveness and high recurrence rate of KCOT, differentiation between KCOT and OOC is important, with respect to their treatment modalities. Such epidemiological pools are also essential for the analysis of geographical distribution of odontogenic tumours.
authors.affiliation: Department of Oral and Maxillofacial Pathology and Microbiology, College of Dental Sciences and Hospital, Davangere, Karnataka, India.
authors.forename: Manickam
authors.initials: M
authors.lastname: Selvamani
authors.affiliation: Department of Oral Pathology, Vivekanandha Dental College for Women, Tiruchengode, Namakkal, Tamil Nadu, India.
authors.forename: Andamuthu Yamuna
authors.initials: AY
authors.lastname: Devi
authors.affiliation: Department of Oral and Maxillofacial Pathology and Microbiology, College of Dental Sciences and Hospital, Davangere, Karnataka, India.
authors.forename: Praveen S
authors.initials: PS
authors.lastname: Basandi
authors.affiliation: Department of Oral and Maxillofacial Pathology and Microbiology, College of Dental Sciences and Hospital, Davangere, Karnataka, India.
authors.forename: G S
authors.initials: GS
authors.lastname: Madhushankari
keywords: Keratocystic odontogenic tumor; World Health Organization; orthokeratinized odontogenic cysts