title: Multiple-frequency excitation wideband MRI (ME-WMRI).
abstract: OBJECTIVE
  In this study multiple-frequency excitation wideband MRI (ME-WMRI), a technique designed to acquire simultaneously excited images without blurring was proposed.
  
  
  METHODS
  ME-WMRI consists of (a) a coherent acquisition sequence that applies refocusing gradient during readout to mitigate signal dephasing, and (b) a signal enhancement procedure that further reduces image blurring. This two-step method was tested on phantom imaging andin vivo imaging with up to 3.84 pixel blur.
  
  
  RESULTS
  Imaging results in both phantom andin vivo show that the lost details were successfully restored in the blur-mitigated images, and the accelerated images were comparable to standard images.
  
  
  CONCLUSIONS
  The proposed ME-WMRI method can effectively undo the image blurring, and thus removes the limitation on fast simultaneous multislice MRI systems with a large acceleration factor.
authors.affiliation: Institute of Biomedical Engineering, National Taiwan University, Taipei 106, Taiwan and MRI/MRS Interdisciplinary Lab, National Taiwan University, Taipei 106, Taiwan.
authors.forename: Edzer L
authors.initials: EL
authors.lastname: Wu
authors.affiliation: Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan.
authors.forename: Tzi-Dar
authors.initials: TD
authors.lastname: Chiueh
authors.affiliation: Institute of Biomedical Engineering, National Taiwan University, Taipei 106, Taiwan; Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan; and MRI/MRS Interdisciplinary Lab, National Taiwan University, Taipei 106, Taiwan.
authors.forename: Jyh-Horng
authors.initials: JH
authors.lastname: Chen
mesh_terms: D000465:Algorithms; D000818:Animals; D016477:Artifacts; D001921:Brain / Q000033:anatomy & histology; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D051379:Mice; D019047:Phantoms, Imaging; D059629:Signal-To-Noise Ratio; D013552:Swine; D013623:Tail / Q000033:anatomy & histology