title: Seizures after overdoses of bupropion intake.
abstract: BACKGROUND
  Bupropion is a new-generation monocyclic antidepressant that has been accidentally found to have potential effects on reducing nicotine addiction. It is structurally similar to stimulants such as amphetamine and inhibits dopamine and noradrenalin reuptake selectively.
  
  
  METHODS
  We report two cases with no history of epilepsy who took oral bupropion for depression and had generalised tonic-clonic type of seizures in their follow-ups.
  
  
  CONCLUSIONS
  After an overdose of bupropion, clinical effects are seen primarily on the neurological, cardiovascular, and gastrointestinal systems. Neurological effects can include tremor, confusion, agitation, hallucinations, coma, and seizures.
authors.affiliation: Department of Emergency Medicine, Selçuk University Selçuklu Faculty of Medicine, Konya, Turkey.
authors.forename: Hasan
authors.initials: H
authors.lastname: Kara
authors.affiliation: Department of Emergency Medicine, Selçuk University Selçuklu Faculty of Medicine, Konya, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Ak
authors.affiliation: Department of Emergency Medicine, Selçuk University Selçuklu Faculty of Medicine, Konya, Turkey.
authors.forename: Ayşegül
authors.initials: A
authors.lastname: Bayır
authors.affiliation: Department of Emergency Medicine, Selçuk University Selçuklu Faculty of Medicine, Konya, Turkey.
authors.forename: Demet
authors.initials: D
authors.lastname: Acar
authors.affiliation: Department of Emergency Medicine, Selçuk University Selçuklu Faculty of Medicine, Konya, Turkey.
authors.forename: Rabia
authors.initials: R
authors.lastname: Istanbulluoğlu
authors.affiliation: Department of Emergency Medicine, Selçuk University Selçuklu Faculty of Medicine, Konya, Turkey.
authors.forename: Selim
authors.initials: S
authors.lastname: Değirmenci
keywords: Bupropion; overdoses; seizures