title: Optical coherence tomography in respiratory science and medicine: from airways to alveoli.
abstract: Optical coherence tomography is a rapidly maturing optical imaging technology, enabling study of the in vivo structure of lung tissue at a scale of tens of micrometers. It has been used to assess the layered structure of airway walls, quantify both airway lumen caliber and compliance, and image individual alveoli. This article provides an overview of the technology and reviews its capability to provide new insights into respiratory disease.
authors.affiliation: Optical & Biomedical Engineering Laboratory, School of Electrical, Electronic & Computer Engineering, The University of Western Australia, Perth, Australia; robert.mclaughlin@uwa.edu.au.
authors.forename: Robert A
authors.initials: RA
authors.lastname: McLaughlin
authors.affiliation: School of Anatomy, Physiology & Human Biology, and Centre for Neonatal Research & Education, School of Paediatrics and Child Health, The University of Western Australia, Crawley, Australia; and.
authors.forename: Peter B
authors.initials: PB
authors.lastname: Noble
authors.affiliation: Optical & Biomedical Engineering Laboratory, School of Electrical, Electronic & Computer Engineering, The University of Western Australia, Perth, Australia; Centre for Microscopy, Characterisation & Analysis, The University of Western Australia, Perth, Australia.
authors.forename: David D
authors.initials: DD
authors.lastname: Sampson
mesh_terms: D000402:Airway Obstruction / Q000175:diagnosis / Q000473:pathology*; D000818:Animals; D003952:Diagnostic Imaging; D006801:Humans; D008168:Lung / Q000473:pathology*; D008171:Lung Diseases / Q000175:diagnosis; D012143:Respiratory Physiological Phenomena; D041623:Tomography, Optical Coherence