title: Helminths in the lungs.
abstract: Parasitic helminths infect well over one billion people and typically cause chronic and recurrent infections that exert a considerable toll on human health and productivity. A significant number of important intestinal- and tissue-dwelling helminth parasites have evolved a scripted migration through select organ systems. Of specific interest here are the helminth parasites that interact with respiratory tissues and the pulmonary immune system. This review will consider the nature of the interactions between helminth parasites and the lung environment, as well as the consequences of these interactions on the evolution of parasitism and host immunity.
authors.affiliation: Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Craig
authors.forename: A L
authors.initials: AL
authors.lastname: Scott
mesh_terms: D000818:Animals; D014943:Global Health; D006373:Helminthiasis / Q000453:epidemiology / Q000276:immunology* / Q000469:parasitology*; D006790:Host-Parasite Interactions / Q000276:immunology; D006801:Humans; D008174:Lung Diseases, Parasitic / Q000453:epidemiology / Q000276:immunology* / Q000469:parasitology*
keywords: filariasis; hookworm; innate immunity; lung inflammation; mucosal immunity; schistosomiasis