title: The case of diagnostics of invasive pulmonary aspergillosis by in vivo probe-based confocal laser endomicroscopy of central and distal airways.
abstract: We present a case of 41-year-old patient with invasive pulmonary aspergillosis (IPA) in which probe-based confocal laser endomicroscopy (pCLE) imaging of central and distal airways was first performed in vivo. pCLE imaging showed the signs of complete or partial destruction of elastin network of alveolar wall with fibrillar branching fluorescent structures in the zone with typical IPA changes on HRCT.
authors.affiliation: Department of Endoscopy Federal Research Clinical Center FMBA of Russia, Moscow 115682, Russia.
authors.forename: Olesya
authors.initials: O
authors.lastname: Danilevskaya
authors.affiliation: Department of Pulmonology Federal Research Clinical Center FMBA of Russia, Moscow 115682, Russia.
authors.forename: Alexander
authors.initials: A
authors.lastname: Averyanov
authors.affiliation: Department of Clinical Mycology North Western State Medical University, Saint Petersburg 194291, Russia.
authors.forename: Nikolay
authors.initials: N
authors.lastname: Klimko
authors.affiliation: Department of Radiology Federal Research Clinical Center FMBA of Russia, Moscow 115682, Russia.
authors.forename: Viktor
authors.initials: V
authors.lastname: Lesnyak
authors.affiliation: Department of Pathology Federal Research Clinical Center FMBA of Russia, Moscow 115682, Russia.
authors.forename: Anastasia
authors.initials: A
authors.lastname: Sorokina
authors.affiliation: Department of Endoscopy Federal Research Clinical Center FMBA of Russia, Moscow 115682, Russia.
authors.forename: Dmitry
authors.initials: D
authors.lastname: Sazonov
authors.affiliation: Department of Pathology Federal Research Clinical Center FMBA of Russia, Moscow 115682, Russia.
authors.forename: Fedor
authors.initials: F
authors.lastname: Zabozlaev
keywords: A. niger; Alveoscopy; Diagnostics; Probe-based confocal laser endomicroscopy (pCLE); Pulmonary invasive aspergillosis