title: Iodine(III)-mediated C-H alkoxylation of aniline derivatives with alcohols under metal-free conditions.
abstract: The development of a novel intermolecular oxidative C-H alkoxylation of aniline derivatives is described under metal-free conditions with high reaction rates at ambient temperature. In the presence of an I(III) oxidant, a range of aldehydes, anilines, and alcohol substrates undergo three-component coupling to produce synthetically useful alkoxyl-substituted N-arylimines. The preliminary mechanism investigations revealed that the transformation proceeds via imines as intermediates.
authors.affiliation: College of Chemistry and Chemical Engineering, Advanced Catalytic Engineering Research Center of the Ministry of Education, Hunan University , Changsha 410082, P.R. China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Jiang
authors.forename: Jing-Yu
authors.initials: JY
authors.lastname: Wang
authors.forename: Cancheng
authors.initials: C
authors.lastname: Guo