title: Surgical management of the juvenile idiopathic arthritis patient with multiple joint involvement.
abstract: Juvenile idiopathic arthritis (JIA) is recognized as a heterogenous group of disorders in which the common factor is persistent arthritis in at least 1 joint occurring before the age of 16 years. Although conservative management with nonsteroidal anti-inflammatory drugs and disease-modifying antirheumatic drugs can be effective, approximately 10% of JIA patients have end-stage degenerative changes requiring total hip arthroplasties (THAs) and total knee arthroplasties (TKAs). This article discusses the overall epidemiology, coordination of care, and medical and surgical management of JIA patients undergoing THA and TKA.
authors.affiliation: Department of Orthopedic Surgery, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA. Electronic address: abdel.matthew@mayo.edu.
authors.forename: Matthew P
authors.initials: MP
authors.lastname: Abdel
authors.affiliation: Division of Adult Reconstruction and Joint Replacement, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.
authors.forename: Mark P
authors.initials: MP
authors.lastname: Figgie
mesh_terms: D000015:Abnormalities, Multiple / Q000209:etiology / Q000601:surgery*; D001171:Arthritis, Juvenile / Q000150:complications / Q000188:drug therapy / Q000601:surgery*; D019644:Arthroplasty, Replacement, Hip; D019645:Arthroplasty, Replacement, Knee; D003191:Comprehensive Health Care / Q000458:organization & administration*; D006801:Humans; D006886:Hydroxychloroquine / Q000008:administration & dosage; D008727:Methotrexate / Q000008:administration & dosage; D019990:Perioperative Care / Q000379:methods; D012086:Reoperation; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
chemical_list: D014409:Tumor Necrosis Factor-alpha; D006886:Hydroxychloroquine; D008727:Methotrexate
keywords: Juvenile idiopathic arthritis; Juvenile rheumatoid arthritis; Total hip arthroplasty; Total knee arthroplasty