title: Use of bivalirudin for anticoagulation during implantation of total artificial heart.
abstract: Heparin-induced thrombocytopenia presents a challenge for anticoagulation techniques during cardiac surgery and ventricular assist device implantation. Bivalirudin is currently recommended for use during cardiopulmonary bypass for patients with heparin-induced thrombocytopenia but requires the use of special techniques to avoid blood stagnation. We report the successful use of bivalirudin during cardiopulmonary bypass for implantation of the Total Artificial Heart with late operative bleeding likely resulting from heavy cell saver use.
authors.forename: Myke
authors.initials: M
authors.lastname: Federman
authors.forename: Douglas
authors.initials: D
authors.lastname: Dragomer
authors.forename: Stuart
authors.initials: S
authors.lastname: Grant
authors.forename: Brian
authors.initials: B
authors.lastname: Reemtsen
authors.forename: Reshma
authors.initials: R
authors.lastname: Biniwale
mesh_terms: D000328:Adult; D000991:Antithrombins / Q000008:administration & dosage; D002315:Cardiopulmonary Bypass / Q000009:adverse effects*; D006354:Heart, Artificial / Q000009:adverse effects*; D006629:Hirudins / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D010446:Peptide Fragments / Q000008:administration & dosage*; D011292:Premedication / Q000379:methods*; D019919:Prosthesis Implantation / Q000009:adverse effects / Q000379:methods*; D011994:Recombinant Proteins / Q000008:administration & dosage; D013927:Thrombosis / Q000209:etiology* / Q000517:prevention & control*; D016896:Treatment Outcome
chemical_list: D000991:Antithrombins; D006629:Hirudins; D010446:Peptide Fragments; D011994:Recombinant Proteins; C074619:bivalirudin