title: Unstrained carbon-carbon bond cleavage.
abstract: This Focus Review presents recent developments in the cleavage of C-C bonds in organic molecules. Significant progress in C-C activation, including the development of a variety of new synthetic strategies, has contributed to the development of this field over the past few decades. Transition-metal-mediated C-C bond cleavage has been shown to be a quite efficient process and several elegant metal-free methods have also recently been developed. Strained rings have been widely used in C-C cleavage transformations; however, unstrained C-C activation has increasingly caught the attention of organic researchers, which inspired us to clarify the developments in this field.
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062 (P. R. China), Fax: (+86) 21-52133654 http://faculty.ecnu.edu.cn/s/641/main.jspy; School of Chemical Engineering, Shandong University of Technology, Zibo 255049 (P. R. China).
authors.forename: Hui
authors.initials: H
authors.lastname: Liu
authors.forename: Minghao
authors.initials: M
authors.lastname: Feng
authors.forename: Xuefeng
authors.initials: X
authors.lastname: Jiang
keywords: CC activation; metal-free synthesis; synthesis design; transition metals; unstrained CC bonds