title: Review of evidence for dietary influences on atopic dermatitis.
abstract: Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting children and adolescents worldwide. The relationship of AD to diet has been a matter of curiosity for many years. Here we look at the evidence in the literature of the association between AD and diet, and the effectiveness of elimination diets and diet supplementation in the management of AD. Several studies have found an association between clinical food allergy and AD, and more recent investigations have also suggested that dietary elements may promote late AD exacerbations. Diet elimination trials in select patients who are clinically allergic to eggs have shown promise in reducing symptoms. Additionally, elimination of food additives in a subgroup of patients was found to be beneficial. Finally, diet supplementations with evening primrose oil and an omega-3 fatty acid (docosahexaenoic acid) may be appropriate in certain AD candidates.
authors.affiliation: Dermatology and Internal Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
authors.forename: S
authors.initials: S
authors.lastname: Mohajeri
authors.forename: S A
authors.initials: SA
authors.lastname: Newman
mesh_terms: D000293:Adolescent; D002648:Child; D003876:Dermatitis, Atopic / Q000178:diet therapy* / Q000209:etiology; D004032:Diet; D019587:Dietary Supplements; D004281:Docosahexaenoic Acids / Q000008:administration & dosage; D021181:Egg Hypersensitivity / Q000150:complications; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage; D005512:Food Hypersensitivity / Q000150:complications*; D006801:Humans; D008041:Linoleic Acids / Q000008:administration & dosage; D031665:Oenothera biennis; D010938:Plant Oils / Q000008:administration & dosage; D017965:gamma-Linolenic Acid / Q000008:administration & dosage
chemical_list: D015525:Fatty Acids, Omega-3; D008041:Linoleic Acids; D010938:Plant Oils; D004281:Docosahexaenoic Acids; C028498:evening primrose oil; D017965:gamma-Linolenic Acid