title: Case of allergic contact dermatitis due to 1,3-butylene glycol.
abstract: 1,3-Butylene glycol (1,3-BG) is widely used in cosmetics, including low-irritant skin care products and topical medicaments, as an excellent and low-irritation humectant. We report a case of allergic contact dermatitis caused by 1,3-BG. A 28-year-old woman suffered from an itchy erythematous eruption on her face. By 2 days of closed patch testing, her own cosmetics and many of the hypo-irritant skin care products showed positive results. A second patch testing showed positive reaction to 1,3-BG (1% and 5%). 1,3-BG was a common component in most of the products that had elicited a positive reaction in the first patch testing. Although allergic contact dermatitis due to 1,3-BG is not so common, we have to consider 1,3-BG as a possible contact allergen in the patients presenting with allergic contact dermatitis due to various cosmetics.
authors.affiliation: Department of Dermatology, Niigata University School of Medicine, Niigata, Japan.
authors.forename: Atsuko
authors.initials: A
authors.lastname: Aizawa
authors.forename: Akiko
authors.initials: A
authors.lastname: Ito
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Masui
authors.forename: Masaaki
authors.initials: M
authors.lastname: Ito
mesh_terms: D000328:Adult; D002072:Butylene Glycols / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D005260:Female; D006801:Humans
chemical_list: D002072:Butylene Glycols; C028491:1,3-butylene glycol
keywords: 1,3-butylene glycol; allergic contact dermatitis; cosmetics; hypo-irritant skin care products; patch testing