title: Copper-catalyzed C(sp2)-H amidation with azides as amino sources.
abstract: A copper-catalyzed C-H amidation process, with azides as amino sources under oxidant-free conditions, has been developed. When N-heterocycles were employed as directing groups, sulfonylazide and benzoylazide could be used as amidating reagents to provide corresponding N-arylamides. When amidines or imine were used, tandem C-N/N-N bond formation occurred to afford indazole derivatives in one pot.
authors.affiliation: State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences , 190 Kaiyuan Avenue, Guangzhou 510530, China.
authors.forename: Jiangling
authors.initials: J
authors.lastname: Peng
authors.forename: Zeqiang
authors.initials: Z
authors.lastname: Xie
authors.forename: Ming
authors.initials: M
authors.lastname: Chen
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.forename: Qiang
authors.initials: Q
authors.lastname: Zhu
mesh_terms: D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D000578:Amidines / Q000737:chemistry; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007097:Imines / Q000737:chemistry; D007191:Indazoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry
chemical_list: D000577:Amides; D000578:Amidines; D001386:Azides; D007097:Imines; D007191:Indazoles; D003300:Copper; D012238:Rhodium