title: [Dissecting cellulitis of the scalp: a retrospective study of 7 cases confirming the efficacy of oral isotretinoin].
abstract: BACKGROUND
  Dissecting cellulitis of the scalp (DCS) is a rare and long-standing disease and its aetiopathogenesis remains unclear. Various therapeutic alternatives exist. We attempted to assess the efficacy of oral isotretinoin in a series of patients.
  
  
  METHODS
  Seven cases of DCS followed and treated by one of the authors at the Sabouraud Centre in the Saint-Louis Hospital between 2007 and 2013 were retrospectively studied and the efficacy of oral isotretinoin was evaluated.
  
  
  RESULTS
  The seven patients included were males aged between 22 and 39 years, with alopecic nodules on the occiput (two cases) or the top of the vertex (five cases). Most patients were given oral isotretinoin at a dosage of 0.75mg/kg/day for at least nine months. The outcome was satisfactory with complete healing of the lesions and good regrowth in all cases. Follow-up after recovery lasted between 16 and 42 months.
  
  
  CONCLUSIONS
  Based on published studies and the results of the present study, oral isotretinoin at a dose of 0.75mg/kg/day may be proposed as first-line treatment for DCS.
authors.affiliation: Faculté de médecine, université de Parakou, BP 123, Parakou, Bénin; Centre Sabouraud, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75010 Paris, France. Electronic address: chkoudoukpo@yahoo.fr.
authors.forename: C
authors.initials: C
authors.lastname: Koudoukpo
authors.affiliation: Centre Sabouraud, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75010 Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Abdennader
authors.affiliation: Service d'anatomo-pathologie, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75010 Paris, France.
authors.forename: B
authors.initials: B
authors.lastname: Cavelier-Balloy
authors.affiliation: Centre Sabouraud, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75010 Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Gasnier
authors.affiliation: Faculté des sciences de la santé de Cotonou, 01 BP 188, Cotonou, Bénin.
authors.forename: H
authors.initials: H
authors.lastname: Yédomon
mesh_terms: D000284:Administration, Oral; D000328:Adult; D002481:Cellulitis / Q000188:drug therapy*; D003879:Dermatologic Agents / Q000008:administration & dosage*; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage*; D008297:Male; D012189:Retrospective Studies; D012536:Scalp Dermatoses / Q000188:drug therapy*; D055815:Young Adult
chemical_list: D003879:Dermatologic Agents; D015474:Isotretinoin
keywords: Alopecia; Alopécie; Cellulite disséquante du cuir chevelu; Dissecting cellulitis of the scalp; Isotrétinoïne; Oral isotretinoin; Traitement; Treatment