title: An osteolytic metastasis of humerus from an asymptomatic squamous cell carcinoma of lung: a rare clinical entity.
abstract: Advanced lung cancer is complicated by skeletal metastases either due to direct extension from adjacent primaries or, more commonly, due to haematogenous dissemination of neoplastic cells. Lumber spine is the most common site for bony metastases in bronchogenic carcinoma. Proximal lone bones, especially humerus, are unusual sites for metastases from lung primaries. Small cell and large cell varieties of lung cancer are most commonly associated with skeletal dissemination. It is also unusual that an asymptomatic squamous cell carcinoma of lung presents with painful, soft tissue swelling with osteolytic metastasis of humerus which is reported in our case. Systemic cytotoxic chemotherapy, local palliative radiotherapy, adequate analgesia, and internal fixation of the affected long bone are different modalities of treatment in this advanced stage of disease. But the prognosis is definitely poor in this stage IV disease.
authors.affiliation: Department of Pulmonary Medicine, Medical College, 88 College Street, Kolkata, West Bengal 700 073, India.
authors.forename: Anirban
authors.initials: A
authors.lastname: Das
authors.affiliation: Department of Pulmonary Medicine, Medical College, 88 College Street, Kolkata, West Bengal 700 073, India.
authors.forename: Sudipta
authors.initials: S
authors.lastname: Pandit
authors.affiliation: Department of Pulmonary Medicine, Medical College, 88 College Street, Kolkata, West Bengal 700 073, India.
authors.forename: Sibes K
authors.initials: SK
authors.lastname: Das
authors.affiliation: Department of Pulmonary Medicine, Medical College, 88 College Street, Kolkata, West Bengal 700 073, India.
authors.forename: Sumitra
authors.initials: S
authors.lastname: Basuthakur
authors.affiliation: Department of Pulmonary Medicine, Medical College, 88 College Street, Kolkata, West Bengal 700 073, India.
authors.forename: Somnath
authors.initials: S
authors.lastname: Das