title: High-frequency oscillatory ventilation in adults: handle with care.
abstract: In the previous issue of Critical Care, Gu and colleagues reported the results of a systematic review and meta-analysis of randomized trials comparing high-frequency oscillatory ventilation (HFOV) with conventional ventilation in adults with acute respiratory distress syndrome (ARDS). In contrast to findings of prior meta-analyses, their main finding was that, despite reducing risks of oxygenation failure, HFOV does not improve survival in adults with ARDS.
authors.affiliation: Interdepartmental Division of Critical Care Medicine, Departments of Medicine and Physiology, and Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto General Hospital, 585 University Avenue, 11 PMB 120, Toronto, ON, M5G 2N2, Canada. n.ferguson@utoronto.ca.|Department of Medicine, Division of Respirology, University Health Network and Mount Sinai Hospital, and the Toronto General Research Institute, 585 University Avenue, 11 PMB 120, Toronto, ON, M5G 2N2, Canada. n.ferguson@utoronto.ca.
authors.forename: Niall D
authors.initials: ND
authors.lastname: Ferguson
mesh_terms: D006612:High-Frequency Ventilation / Q000379:methods*; D006801:Humans; D016032:Randomized Controlled Trials as Topic / Q000379:methods*; D012128:Respiratory Distress Syndrome / Q000175:diagnosis* / Q000628:therapy*