title: Neuroscience: waiting for serotonin.
abstract: Serotonin dysfunction is implicated in many neuropsychiatric disorders yet the precise behavioral functions of this neuromodulator are not well understood. A new study employs optogenetic methods to activate serotonin neurons during an effort-demanding waiting behavior and demonstrates that serotonin release increases patience, the capacity for self-control.
authors.affiliation: Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.
authors.forename: Sachin
authors.initials: S
authors.lastname: Ranade
authors.affiliation: Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.
authors.forename: Hyun-Jae
authors.initials: HJ
authors.lastname: Pi
authors.affiliation: Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA. Electronic address: kepecs@cshl.edu.
authors.forename: Adam
authors.initials: A
authors.lastname: Kepecs
mesh_terms: D000818:Animals; D000075402:Channelrhodopsins; D065847:Dorsal Raphe Nucleus / Q000528:radiation effects*; D008027:Light; D008297:Male; D012201:Reward; D059326:Serotonergic Neurons / Q000528:radiation effects*; D012701:Serotonin / Q000378:metabolism*
chemical_list: D000075402:Channelrhodopsins; D012701:Serotonin