title: Effect of thyroid on lipid profile and renal function: an observational study from tertiary care centre of tribal region of bastar.
abstract: BACKGROUND
  Thyroid hormone is a key substance in normal homeostasis, having variable influence on cell metabolism on different organs. Very little is known about the prevalence of thyroid disorders from our region.
  
  
  OBJECTIVE
  This study was conducted with the aim of finding prevalence of thyroid disorder and relation of thyroid hormone with renal function and cholesterol metabolism.
  
  
  METHODS
  A total of 96 ambulatory patients were taken for study. Serum samples were collected and evaluated for triiodothyronine, thyroxine, thyroid-stimulating hormone, urea, creatinine, total cholesterol, triglyceride (TG), low density lipoprotein (LDL), very low density lipoprotein and high density lipoprotein (HDL). Analysis of variance and t-test were used to find a significant difference among the groups.
  
  
  RESULTS
  Prevalance of thyroid disorder among suspected patients was 64/96 (66%), of which 36/64 (56.3%) were hypothyroid and 28/64 (43.8%) were hyperthyroid. No relation was found with renal function, but cholesterol was found high (>250 mg/dl) among hypothyroid patients and significant increase in TG, LDL levels and significant decrease was in HDL.
  
  
  CONCLUSIONS
  Thyroid disorder is high among subjects with hypercholesterolemia. This underscores the need to evaluate for thyroid disorder in hypercholesterolemic patients and vice-versa.
authors.affiliation: Department of Biochemistry, Lt. Shri Baliram Kashyap Memorial Government Medical College, Jagdalpur, Chhattisgarh, India.
authors.forename: A
authors.initials: A
authors.lastname: Bansal
authors.affiliation: Department of Community Medicine, UP Rural Institute of Medical Sciences and Research, Saifai, Etawah, Uttar Pradesh, India.
authors.forename: A
authors.initials: A
authors.lastname: Kaushik
authors.affiliation: Department of Biochemistry, Lt. Shri Baliram Kashyap Memorial Government Medical College, Jagdalpur, Chhattisgarh, India.
authors.forename: H
authors.initials: H
authors.lastname: Sarathe
keywords: Creatinine; Hyperthyroidism; Hypothyroidism; Serum cholesterol; Tribal; Urea