title: Cryptogenic organizing pneumonia in Sweet's syndrome: case report and review of the literature.
abstract: OBJECTIVE
  Sweet's syndrome or acute febrile neutrophilic dermatosis is characterized by fever, leukocytosis and tender erythematous plaques, which show infiltration by mature neutrophils on histological examination. Pulmonary involvement is rare in Sweet's syndrome.
  
  
  METHODS
  We describe the case of a 17-year-old man with a myelodysplastic syndrome following therapy for Hodgkin's lymphoma who developed Sweet's syndrome and cryptogenic organizing pneumonia. In addition, we conducted a review of the related English literature.
  
  
  RESULTS
  Literature review yielded six similar reports of biopsy-proven cryptogenic organizing pneumonia associated with Sweet's syndrome. We present the clinical and laboratory characteristics, as well as the response to treatment, of all cases of cryptogenic organizing pneumonia reported in patients with Sweet's syndrome.
  
  
  CONCLUSIONS
  Cryptogenic organizing pneumonia is a rare manifestation of Sweet's syndrome, which may be complicated by respiratory failure. Prompt treatment with corticosteroids usually leads to clinical and radiographic improvement.
authors.affiliation: Department of Pathophysiology, 'Laiko' Hospital, University of Athens Medical School, Athens, Greece.
authors.forename: Elias
authors.initials: E
authors.lastname: Tzelepis
authors.affiliation: Department of Pathophysiology, 'Laiko' Hospital, University of Athens Medical School, Athens, Greece.
authors.forename: Christos F
authors.initials: CF
authors.lastname: Kampolis
authors.affiliation: Department of Pathophysiology, 'Laiko' Hospital, University of Athens Medical School, Athens, Greece.
authors.forename: Ioanna
authors.initials: I
authors.lastname: Vlachadami
authors.affiliation: Department of Pediatrics, University of Athens Medical School, Athens, Greece.
authors.forename: Maria
authors.initials: M
authors.lastname: Moschovi
authors.affiliation: Department of Pathology, Henry Dunant Hospital, Athens, Greece.
authors.forename: Maria
authors.initials: M
authors.lastname: Alamani
authors.affiliation: Department of Pathophysiology, 'Laiko' Hospital, University of Athens Medical School, Athens, Greece.
authors.forename: Gregory
authors.initials: G
authors.lastname: Kaltsas
mesh_terms: D061605:Administration, Intravenous; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage* / Q000627:therapeutic use; D018549:Cryptogenic Organizing Pneumonia / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D006689:Hodgkin Disease / Q000150:complications / Q000188:drug therapy; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage* / Q000627:therapeutic use; D009190:Myelodysplastic Syndromes / Q000150:complications / Q000188:drug therapy; D016463:Sweet Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D008775:Methylprednisolone
keywords: Sweet's syndrome; cryptogenic organizing pneumonia (COP); myelodysplastic syndrome; neutrophilic dermatosis