title: Identification of risk factors for intraoperative hemobilia and its correlation with early postoperative complications in patients with hepatolithiasis.
abstract: BACKGROUND
  This study intends to determine the risk factor(s) for intraoperative hemobilia in patients with hepatolithiasis and examine whether the occurrence of intraoperative hemobilia influences the rate of early postoperative complications.
  
  
  METHODS
  A retrospective analysis of 867 eligible patients was performed. Patients were divided into 2 groups: group A (hemobilia, n = 76) and group B (nonhemobilia, n = 791).
  
  
  RESULTS
  The incidence of intraoperative hemobilia was 8.8% (76/867). Independent risk factors of intraoperative hemobilia for patients with hepatolithiasis were interval between surgery and latest attack of acute cholangitis less than or equal to 38.8 days; preoperative attack of acute severe cholangitis; and intrahepatic duct stricture. Group A had a higher incidence of early postoperative complications than group B. Shorter interval between surgery and latest attack of acute cholangitis correlated with intraoperative hemobilia and postoperative complications.
  
  
  CONCLUSIONS
  The severity and time of onset of preoperative acute cholangitis influence the risk of intraoperative hemobilia, which is positively correlated with early postoperative complications.
authors.affiliation: Department of Hepatobiliary Surgery, Nanfang Hospital, Southern Medical University, No. 1838, North Guangzhou Avenue, Guangzhou 510515, China. Electronic address: guoweizhang77@hotmail.com.
authors.forename: Guo-wei
authors.initials: GW
authors.lastname: Zhang
authors.affiliation: Department of Hepatobiliary Surgery, Nanfang Hospital, Southern Medical University, No. 1838, North Guangzhou Avenue, Guangzhou 510515, China.
authors.forename: Jian-hua
authors.initials: JH
authors.lastname: Lin
authors.affiliation: Department of Hepatobiliary Surgery, Nanfang Hospital, Southern Medical University, No. 1838, North Guangzhou Avenue, Guangzhou 510515, China.
authors.forename: Jian-ping
authors.initials: JP
authors.lastname: Qian
authors.affiliation: Department of Hepatobiliary Surgery, Nanfang Hospital, Southern Medical University, No. 1838, North Guangzhou Avenue, Guangzhou 510515, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Zhou
mesh_terms: D002761:Cholangitis / Q000453:epidemiology / Q000209:etiology*; D002769:Cholelithiasis / Q000601:surgery*; D005260:Female; D006431:Hemobilia / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D015994:Incidence; D007431:Intraoperative Complications / Q000453:epidemiology / Q000209:etiology*; D008107:Liver Diseases / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology*; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors
keywords: Acute cholangitis; Hemobilia; Hepatolithiasis; Postoperative complications