title: Use of various CT imaging methods for diagnosis of acute ischemic cerebrovascular disease.
abstract: Thirty-four patients with cerebral infarction and 18 patients with transient ischemic attack were examined by multi-slice spiral CT scan, CT perfusion imaging, and CT angiography within 6 hours after onset. By CT perfusion imaging, 29 cases in the cerebral infarction group and 10 cases in the transient ischemic attack group presented with abnormal blood flow perfusion, which corresponded to the clinical symptoms. By CT angiography, various degrees of vascular stenosis could be detected in 41 patients, including 33 in the cerebral infarction group and eight in the transient ischemic attack group. The incidence of intracranial artery stenosis was higher than that of extracranial artery stenosis. The intracranial artery stenosis was located predominantly in the middle cerebral artery and carotid artery siphon, while the extracranial artery stenosis occurred mainly in the bifurcation of the common carotid artery and the opening of the vertebral artery. There were 34 cases (83%) with convict vascular stenosis and perfusion abnormalities, and five cases (45%) with perfusion abnormalities but without convict vascular stenosis. The incidence of cerebral infarction in patients with National Institutes of Health Stroke Scale scores ≥ 5 points during onset was significantly higher than that in patients with National Institutes of Health Stroke Scale scores < 5 points. These experimental findings indicate that the combined application of various CT imaging methods allows early diagnosis of acute ischemic cerebrovascular disease, which can comprehensively analyze the pathogenesis and severity of acute ischemic cerebrovascular disease at the morphological and functional levels.
authors.affiliation: Department of Radiology, the First Affiliated Hospital of Liaoning Medical University, Jinzhou 121001, Liaoning Province, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Wang
authors.affiliation: Department of Neurology, the First Affiliated Hospital of Liaoning Medical University, Jinzhou 121001, Liaoning Province, China.
authors.forename: Xue
authors.initials: X
authors.lastname: Cheng
authors.affiliation: Department of Radiology, the First Affiliated Hospital of Liaoning Medical University, Jinzhou 121001, Liaoning Province, China.
authors.forename: Xianglin
authors.initials: X
authors.lastname: Zhang
keywords: CT angiography; CT perfusion imaging; cerebral infarction; clinical practice; diagnosis; grants-supported paper; ischemic cerebrovascular disease; multi-slice spiral CT; neural regeneration; neuroimaging; neurological function deficit; neuroregeneration; perfusion; photographs-containing paper; transient ischemic attack