title: Dynamic regulation of endolysosomal programs drives melanoma progression.
abstract: The small GTPase RAB7 is a lineage-specific driver of melanoma that is regulated by MYC and SOX10.
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor / Q000378:metabolism*; D019070:Cell Lineage; D006801:Humans; D008247:Lysosomes / Q000201:enzymology*; D008545:Melanoma / Q000201:enzymology*; D012878:Skin Neoplasms / Q000201:enzymology*; D020691:rab GTP-Binding Proteins / Q000378:metabolism*
chemical_list: D014408:Biomarkers, Tumor; D020691:rab GTP-Binding Proteins