title: Controlled regiodivergent C-H bond activation of imidazo[1,5-a]pyridine via synergistic cooperation between aluminum and nickel.
abstract: The catalytic method features a cooperative interaction between Ni and Al imparting remote C-H alkenylation at the C5 position of imidazo[1,5-a]pyridine with alkynes at mild conditions. Exclusion of AlMe3 switches the selectivity to the C3 position. Reactions with styrene and other olefinic substrates affording C5-adducts by Ni/Al catalysis are also included.
authors.affiliation: Institute of Chemistry, Academia Sinica , Nangang, Taipei 11529, Taiwan, Republic of China.
authors.forename: Ming-Shiuan
authors.initials: MS
authors.lastname: Yu
authors.forename: Wei-Chih
authors.initials: WC
authors.lastname: Lee
authors.forename: Chih-Hao
authors.initials: CH
authors.lastname: Chen
authors.forename: Fu-Yu
authors.initials: FY
authors.lastname: Tsai
authors.forename: Tiow-Gan
authors.initials: TG
authors.lastname: Ong