title: Prolonged fever and splenic lesions caused by Malassezia restricta in an immunocompromised patient.
abstract: Malassezia species are commonly found on human skin as commensals but can cause invasive infections in premature infants and immunocompromised hosts. Due to their fastidious growth, diagnosis of Malassezia infections can prove challenging. Molecular techniques can aid in diagnosis and treatment of invasive infections. We describe the case of a pediatric oncology patient with splenic lesions secondary to Malassezia restricta.
authors.affiliation: Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA.
authors.forename: Annabelle
authors.initials: A
authors.lastname: de St Maurice
authors.forename: Haydar
authors.initials: H
authors.lastname: Frangoul
authors.forename: Alice
authors.initials: A
authors.lastname: Coogan
authors.forename: John V
authors.initials: JV
authors.lastname: Williams
mesh_terms: D019797:3-Iodobenzylguanidine / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002405:Catheterization, Central Venous; D002648:Child; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005260:Female; D005335:Fever of Unknown Origin / Q000209:etiology*; D006801:Humans; D016867:Immunocompromised Host; D008290:Malassezia / Q000302:isolation & purification*; D009181:Mycoses / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D009447:Neuroblastoma / Q000276:immunology* / Q000628:therapy; D013158:Splenic Diseases / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D033581:Stem Cell Transplantation
chemical_list: D000970:Antineoplastic Agents; D019797:3-Iodobenzylguanidine
keywords: hepatosplenic candidiasis; immunodeficiency; malassezia