title: Multimodal imaging for improved diagnosis and treatment of cancers.
abstract: The authors review methods for image-guided diagnosis and therapy that increase precision in the detection, characterization, and localization of many forms of cancer to achieve optimal target definition and complete resection or ablation. A new model of translational, clinical, image-guided therapy research is presented, and the Advanced Multimodality Image-Guided Operating (AMIGO) suite is described. AMIGO was conceived and designed to allow for the full integration of imaging in cancer diagnosis and treatment. Examples are drawn from over 500 procedures performed on brain, neck, spine, thorax (breast, lung), and pelvis (prostate and gynecologic) areas and are used to describe how they address some of the many challenges of treating brain, prostate, and lung tumors. Cancer 2015;121:817-827. © 2014 American Cancer Society.
authors.affiliation: Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
authors.forename: Clare M C
authors.initials: CM
authors.lastname: Tempany
authors.forename: Jagadeesan
authors.initials: J
authors.lastname: Jayender
authors.forename: Tina
authors.initials: T
authors.lastname: Kapur
authors.forename: Raphael
authors.initials: R
authors.lastname: Bueno
authors.forename: Alexandra
authors.initials: A
authors.lastname: Golby
authors.forename: Nathalie
authors.initials: N
authors.lastname: Agar
authors.forename: Ferenc A
authors.initials: FA
authors.lastname: Jolesz
mesh_terms: D003952:Diagnostic Imaging / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D064847:Multimodal Imaging / Q000295:instrumentation / Q000379:methods*; D009369:Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy; D011859:Radiography
keywords: brain tumor; interventional magnetic resonance imaging; intraoperative monitoring; lung cancer; mass spectroscopy; multimodal imaging; neuroimaging; neuronavigation; prostate biopsy; prostate cancer