title: Intra-gastric pressures in neonates receiving bubble CPAP.
abstract: OBJECTIVE
  To study intra-gastric pressures in neonates receiving bubble continuous positive airway pressure (BCPAP) by nasopharyngeal prong.
  
  
  METHODS
  Twenty seven neonates were recruited for the study. BCPAP pressure of 6 cm water was used in all the neonates. A pressure sensor attached to orogastric tube, measured the intra-gastric pressure prior to starting BCPAP and again between 30 and 90 min of BCPAP. The clinical variables like Downe's score, oxygen saturation, venous blood gas pH, pCO(2) and abdominal girth were recorded alongside with pressure readings.
  
  
  RESULTS
  BCPAP resulted in improvement (p < 0.05) in parameters of respiratory distress such as Downe's score (DS), oxygen saturation (SpO(2)) and venous blood gas parameters (pH, pCO(2)). There was no statistical significant increase in intra-gastric pressures (p = 0.834). There were no gastrointestinal complications; abdominal distention, necrotising enterocolitis or gastric perforation during the study.
  
  
  CONCLUSIONS
  Nasopharyngeal BCPAP at 6 cm of water pressure is an effective modality of treating babies with respiratory distress and the present study shows that it is not associated with a significant rise in intra-gastric pressures.
authors.affiliation: Department of Pediatrics and Neonatology, St. Stephen's Hospital, Tis Hazari, New Delhi, 110054, India, drprashant.tyagi@gmail.com.
authors.forename: Prashant
authors.initials: P
authors.lastname: Tyagi
authors.forename: Neeraj
authors.initials: N
authors.lastname: Gupta
authors.forename: Akanksha
authors.initials: A
authors.lastname: Jain
authors.forename: Pramod
authors.initials: P
authors.lastname: Upadhyay
authors.forename: Jacob
authors.initials: J
authors.lastname: Puliyel
mesh_terms: D045422:Continuous Positive Airway Pressure / Q000009:adverse effects / Q000379:methods; D005260:Female; D005767:Gastrointestinal Diseases / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D007194:India; D007231:Infant, Newborn; D008297:Male; D008365:Manometry / Q000379:methods; D011446:Prospective Studies; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*; D016896:Treatment Outcome