title: Novel salicylaldehyde derivatives as fluorescence turn-on sensors for cyanide ion.
abstract: A novel series of fluorescent probes containing diphenylacetylene as fluorogenic units and salicylaldehyde as a CN(-) receptor were successfully synthesized by using sonogashira coupling. In the presence of Triton-X 100 non-ionic surfactant, the fluorophores exhibited fluorescence "turn-on" in response to CN(-) in aqueous media with the detection limit of 1.6 μM. The turn-on signal is the result of the conversion of the aldehyde to cyanohydrin via the internal acid catalyzed addition of cyanide. Using paper sensor strips, a naked eye detection of cyanide is possible down to 5 nmol.
authors.affiliation: Department of Chemistry, Faculty of Science, King Mongkut's University of Technology Thonburi, Bangkok 10140, Thailand.
authors.forename: Nakorn
authors.initials: N
authors.lastname: Niamnont
authors.affiliation: Organic Synthesis Unit, Department of Chemistry, Faculty of Science and Nanotec-CU Center of Excellence on Food and Agriculture Chulalongkorn University, Bangkok 10330, Thailand.
authors.forename: Akachai
authors.initials: A
authors.lastname: Khumsri
authors.affiliation: Organic Synthesis Unit, Department of Chemistry, Faculty of Science and Nanotec-CU Center of Excellence on Food and Agriculture Chulalongkorn University, Bangkok 10330, Thailand.
authors.forename: Apiwat
authors.initials: A
authors.lastname: Promchat
authors.affiliation: National Nanotechnology Center, National Science and Technology Development Agency, Pathumthani 12120, Thailand.
authors.forename: Gamolwan
authors.initials: G
authors.lastname: Tumcharern
authors.affiliation: Organic Synthesis Unit, Department of Chemistry, Faculty of Science and Nanotec-CU Center of Excellence on Food and Agriculture Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: smongkol@chula.ac.th.
authors.forename: Mongkol
authors.initials: M
authors.lastname: Sukwattanasinitt
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D003486:Cyanides / Q000032:analysis*; D005453:Fluorescence
chemical_list: D000447:Aldehydes; D003486:Cyanides; C013243:salicylaldehyde
keywords: Cyanide; Fluorescence; Nucleophilic addition; Sensor; Water analysis