title: Hepatic angiosarcoma with multiple metastases in a young man.
abstract: Hepatic angiosarcoma, also called Kupffer's sarcoma, is a malignant mesenchymal neoplasm of endothelial cells, represents less than two percent of all primary liver neoplasm. Hepatic angiosarcoma is an infrequent and difficult-to-diagnose disease, mostly discovered by chance. Because of its rapid progression and usually fatal outcome, early diagnosis is necessary and complete surgical resection is the key to improve prognosis, but the neoplasm is often disseminated at the time of diagnosis, making resection impossible. Rare cases of hepatic angiosarcoma have been reported in the literature. Here, we report a case of hepatic angiosarcoma with spleen, lungs, right atrium and spine infiltration. Contrast enhanced abdomen CT and MRI scans revealed multiple nodules in the liver and spleen with rich blood supply, at the same time many metastases were noticed at bilateral lungs, right atrium and spine. The lesions rapidly deteriorated during the 2 months following the exams. The diagnosis of hepatic angiosarcoma was made after an open biopsy.
authors.affiliation: 1 Department of Radiology, 2 Department of Pathology, 3 Department of Hepatology, Shenzhen Third People's Hospital, Shenzhen 518112, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Huang
authors.affiliation: 1 Department of Radiology, 2 Department of Pathology, 3 Department of Hepatology, Shenzhen Third People's Hospital, Shenzhen 518112, China.
authors.forename: Xiao-Hua
authors.initials: XH
authors.lastname: Le
authors.affiliation: 1 Department of Radiology, 2 Department of Pathology, 3 Department of Hepatology, Shenzhen Third People's Hospital, Shenzhen 518112, China.
authors.forename: Bo-Ping
authors.initials: BP
authors.lastname: Zhou
authors.affiliation: 1 Department of Radiology, 2 Department of Pathology, 3 Department of Hepatology, Shenzhen Third People's Hospital, Shenzhen 518112, China.
authors.forename: Pu-Xuan
authors.initials: PX
authors.lastname: Lu
keywords: Hepatic angiosarcoma; computed tomography; magnetic resonance imaging