title: Childhood brain tumor epidemiology: a brain tumor epidemiology consortium review.
abstract: Childhood brain tumors are the most common pediatric solid tumor and include several histologic subtypes. Although progress has been made in improving survival rates for some subtypes, understanding of risk factors for childhood brain tumors remains limited to a few genetic syndromes and ionizing radiation to the head and neck. In this report, we review descriptive and analytical epidemiology childhood brain tumor studies from the past decade and highlight priority areas for future epidemiology investigations and methodological work that is needed to advance our understanding of childhood brain tumor causes. Specifically, we summarize the results of a review of studies published since 2004 that have analyzed incidence and survival in different international regions and that have examined potential genetic, immune system, developmental and birth characteristics, and environmental risk factors. Cancer Epidemiol Biomarkers Prev; 23(12); 2716-36. ©2014 AACR.
authors.affiliation: Brown School Masters of Public Health Program, Washington University in St. Louis, St. Louis, Missouri.
authors.forename: Kimberly J
authors.initials: KJ
authors.lastname: Johnson
authors.affiliation: American Childhood Cancer Organization, Kensington, Maryland.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Cullen
authors.affiliation: Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio.
authors.forename: Jill S
authors.initials: JS
authors.lastname: Barnholtz-Sloan
authors.affiliation: Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio.
authors.forename: Quinn T
authors.initials: QT
authors.lastname: Ostrom
authors.affiliation: Centre for Research in Environmental Epidemiology, Carrer Doctor Aiguader, Barcelona, Spain. Universitat Pompeu Fabra, Plaça de la Mercè, Barcelona, Spain. CIBER Epidemiología y Salud Pública, Carrer Casanova, Barcelona, Spain.
authors.forename: Chelsea E
authors.initials: CE
authors.lastname: Langer
authors.affiliation: Centre for Research in Environmental Epidemiology, Carrer Doctor Aiguader, Barcelona, Spain. Universitat Pompeu Fabra, Plaça de la Mercè, Barcelona, Spain. CIBER Epidemiología y Salud Pública, Carrer Casanova, Barcelona, Spain. McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada.
authors.forename: Michelle C
authors.initials: MC
authors.lastname: Turner
authors.affiliation: Department of Preventive Medicine, University of Southern California, USC/Norris Comprehensive Cancer Center, Los Angeles, California.
authors.forename: Roberta
authors.initials: R
authors.lastname: McKean-Cowdin
authors.affiliation: Division of Epidemiology, College of Public Health, The Ohio State University, Columbus, Ohio.
authors.forename: James L
authors.initials: JL
authors.lastname: Fisher
authors.affiliation: Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, Texas. Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas.
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Lupo
authors.affiliation: Division of Neurology, Stanford University, Palo Alto, California.
authors.forename: Sonia
authors.initials: S
authors.lastname: Partap
authors.affiliation: Division of Epidemiology, College of Public Health, The Ohio State University, Columbus, Ohio.
authors.forename: Judith A
authors.initials: JA
authors.lastname: Schwartzbaum
authors.affiliation: Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, Texas. Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas. scheurer@bcm.edu.
authors.forename: Michael E
authors.initials: ME
authors.lastname: Scheurer
mesh_terms: D001932:Brain Neoplasms / Q000453:epidemiology*; D002648:Child; D006801:Humans; D012307:Risk Factors