title: Thyroid-stimulating hormone-secreting ectopic pituitary adenoma of the nasopharynx.
abstract: Thyroid-stimulating hormone-secreting ectopic pituitary adenoma of the nasopharynx is highly unusual, with only three reported cases in the world literature. We describe the clinical presentation and radiologic findings in one patient with such rare lesions. A 46-year-old male with typical symptoms of Grave's disease was found to have a mass on magnetic resonance imaging. An otolaryngologic examination revealed a nasopharyngeal mass lesion, which was endoscopically resected. The results of immunohistochemical staining for thyroid-stimulating hormone were positive. After the resection, the patient's TSH was within normal limits. The clinical significance of the case and a brief literature review are presented.
authors.affiliation: Department of Otorhinolaryngology - Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita, Japan; Department of Otorhinolaryngology - Head and Neck Surgery, Osaka Rosai Hospital, Sakai, Japan. Electronic address: snishiike@orh.go.jp.
authors.forename: Suetaka
authors.initials: S
authors.lastname: Nishiike
authors.affiliation: Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
authors.forename: Ke-ita
authors.initials: KI
authors.lastname: Tatsumi
authors.affiliation: Department of Otorhinolaryngology - Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Shikina
authors.affiliation: Department of Otorhinolaryngology - Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
authors.forename: Chisako
authors.initials: C
authors.lastname: Masumura
authors.affiliation: Department of Otorhinolaryngology - Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
authors.forename: Hidenori
authors.initials: H
authors.lastname: Inohara
mesh_terms: D000236:Adenoma / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism; D002828:Choristoma / Q000175:diagnosis*; D006801:Humans; D006980:Hyperthyroidism / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009302:Nasopharyngeal Diseases / Q000175:diagnosis*; D010902:Pituitary Gland; D010911:Pituitary Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism; D013972:Thyrotropin / Q000378:metabolism*
chemical_list: D013972:Thyrotropin
keywords: Ectopic pituitary adenoma; Extracranial; Hyperthyroidism; Rathke's pouch; TSH