title: Decoding calcium signaling across the nucleus.
abstract: Calcium (Ca(2+)) is an important multifaceted second messenger that regulates a wide range of cellular events. A Ca(2+)-signaling toolkit has been shown to exist in the nucleus and to be capable of generating and modulating nucleoplasmic Ca(2+) transients. Within the nucleus, Ca(2+) controls cellular events that are different from those modulated by cytosolic Ca(2+). This review focuses on nuclear Ca(2+) signals and their role in regulating physiological and pathological processes.
authors.affiliation: Department of Physiology and Biophysics, Federal University of Minas Gerais, Belo Horizonte, Brazil;
authors.forename: André G
authors.initials: AG
authors.lastname: Oliveira
authors.affiliation: Department of Physiology and Biophysics, Federal University of Minas Gerais, Belo Horizonte, Brazil; Molecular Medicine, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil; and.
authors.forename: Erika S
authors.initials: ES
authors.lastname: Guimarães
authors.affiliation: Department of Physiology and Biophysics, Federal University of Minas Gerais, Belo Horizonte, Brazil;
authors.forename: Lídia M
authors.initials: LM
authors.lastname: Andrade
authors.affiliation: Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
authors.forename: Gustavo B
authors.initials: GB
authors.lastname: Menezes
authors.affiliation: Department of Physiology and Biophysics, Federal University of Minas Gerais, Belo Horizonte, Brazil; leitemd@ufmg.br.
authors.forename: M
authors.initials: M
authors.lastname: Fatima Leite
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D020013:Calcium Signaling / Q000502:physiology*; D002467:Cell Nucleus / Q000378:metabolism*; D006801:Humans; D012097:Repressor Proteins / Q000378:metabolism
chemical_list: D012097:Repressor Proteins; D000255:Adenosine Triphosphate; D002118:Calcium