title: Poorly differentiated synovial sarcoma in the wrist--case report.
abstract: Synovial sarcomas are rare malignant tumors affecting mainly young adults, presenting as a slow growth mass located in deep soft tissues of extremities, near the joints. In this report a 34-year-old male patient, presented an ulcerovegetative lesion on the right wrist which was completely excised. Histopathology and immunohistochemistry confirmed synovial sarcomas with poorly differentiated cells. This patient presented 11 months later with ipsilateral axillary lymph node metastasis, which emphasizes the unfavorable prognosis of this synovial sarcoma variant. The indolent growth pattern of this sarcoma justifies the well circumscribed initial stages, which progressively infiltrate adjacent structures with lung metastasis (80%) and lymph node involvement (20%) and thus corroborates the importance of early diagnosis and proper treatment.
authors.affiliation: Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, AM, Brazil.
authors.forename: Daniela Cristina Caetano
authors.initials: DC
authors.lastname: Maia
authors.affiliation: Universidade Federal do Amazonas, Manaus, AM, Brazil.
authors.forename: Carla Kellen da Silva
authors.initials: CK
authors.lastname: Menezes
authors.affiliation: Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, AM, Brazil.
authors.forename: Thales Costa
authors.initials: TC
authors.lastname: Bastos
authors.affiliation: Universidade Federal do Amazonas, Manaus, AM, Brazil.
authors.forename: Luiz Carlos de Lima
authors.initials: LC
authors.lastname: Ferreira
authors.affiliation: Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, AM, Brazil.
authors.forename: Fabio
authors.initials: F
authors.lastname: Francesconi
mesh_terms: D000328:Adult; D001706:Biopsy; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D013584:Sarcoma, Synovial / Q000473:pathology*; D012867:Skin / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000473:pathology*; D014953:Wrist