title: Studies on repellent activity of seed oils alone and in combination on mosquito, Aedes aegypti.
abstract: The study was undertaken to investigate the relative repellency of Pongamia pinnata and Azadirachta indica seed oils on vector mosquito, Aedes aegypti under laboratory conditions. The repellents were formulated into 3 groups: seed oils, their mixture and combination of seed oils with three carrier oils viz. olive, mustard and coconut oil. Different formulations of each oil were tested at the concentrations of 1% and 5% on human baits. Efficiency was assessed, based on the total protection time; biting rate and percent protection provided by each formulation. Results showed that 5% formulation of the Pongamia pinnata and Azadirachta indica seed oils, mixed in 1:1 ratio exhibited highest percentage repellency of 85%, protection time of 300 min and bite rate of 6%. 5% concentration of A. indica and P. pinnata seed oil in mustard oil base offered 86.36% and 85% protection respectively with total protection time of 230 and 240 min respectively. The study confirms that Azadirachta indica and Pongamia pinnata have mosquito-repellent potential. When mixed in different ratios or with some carrier oil their efficacy increases 2-fold in some cases. These formulations are very promising for topical use (> 5 hrs complete protection) and are comparable to the protection provided by advanced Odomos mosquito repellent cream available commercially and thus are recommended for field trial.
authors.forename: Y
authors.initials: Y
authors.lastname: Mukesh
authors.forename: P
authors.initials: P
authors.lastname: Savitri
authors.forename: R
authors.initials: R
authors.lastname: Kaushik
authors.forename: N P
authors.initials: NP
authors.lastname: Singh
mesh_terms: D000330:Aedes; D000818:Animals; D031601:Azadirachta; D004357:Drug Synergism; D005260:Female; D005989:Glycerides; D006801:Humans; D007302:Insect Repellents; D010938:Plant Oils; D052596:Pongamia; D013729:Terpenes
chemical_list: D005989:Glycerides; D007302:Insect Repellents; D010938:Plant Oils; D013729:Terpenes; C002443:neem oil