title: Balanced chromosomal translocation of chromosomes 6 and 7: a rare male factor of spontaneous abortions.
abstract: BACKGROUND
  Carriers of structural chromosomal rearrangements such as Robertsonian or reciprocal translocations have an increased risk of spontaneous abortion and producing offspring with genetic abnormalities.
  
  
  METHODS
  We report a man with balanced chromosomal translocations located at 6p22, and 7q22. His wife has a history of four spontaneous abortions.
  
  
  CONCLUSIONS
  Couples with a history of abortions should be investigated cytogenetically, after other causes of miscarriages are excluded. The possibility of spontaneous abortions can be reduced with preimplantation genetic diagnosis (PGD) before embryo transfer.
authors.affiliation: Department of Urology, Kahramanmaraş Sütçü İmam University Faculty of Medicine, Kahramanmaraş, Turkey.
authors.forename: Sefa
authors.initials: S
authors.lastname: Resim
authors.affiliation: Department of Urology, İstanbul University Faculty of Medicine, İstanbul, Turkey.
authors.forename: Ateş
authors.initials: A
authors.lastname: Kadıoğlu
authors.affiliation: Department of Internal Diseases, İstanbul University Faculty of Medicine, İstanbul, Turkey.
authors.forename: Tolga
authors.initials: T
authors.lastname: Akman
authors.affiliation: Department of Internal Diseases, İstanbul University Faculty of Medicine, İstanbul, Turkey.
authors.forename: Ayşe Gül
authors.initials: AG
authors.lastname: Bayrak
authors.affiliation: Department of Urology, Kahramanmaraş Sütçü İmam University Faculty of Medicine, Kahramanmaraş, Turkey.
authors.forename: Erkan
authors.initials: E
authors.lastname: Efe
keywords: Balanced chromosomal translocation; preimplantation genetic diagnosis; spontaneous abortions