title: Copper-mediated intramolecular oxidative C-H/N-H cross-coupling of α-alkenoyl ketene N,S-acetals to synthesize pyrrolone derivatives.
abstract: CuCl2 and CuBr2-mediated intramolecular oxidative C-H/N-H cross-coupling/halogenation of β-thioalkyl-substituted α-alkenoyl ketene N,S-acetals occurred efficiently, affording 4-halo-5-thioalkyl-3-pyrrolones. Tunable C-S and C-halo bond transformations of the resultant pyrrolone derivatives led to highly functionalized N-heterocyclic compounds.
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China. zkyu@dicp.ac.cn.
authors.forename: Fei
authors.initials: F
authors.lastname: Huang
authors.forename: Ping
authors.initials: P
authors.lastname: Wu
authors.forename: Liandi
authors.initials: L
authors.lastname: Wang
authors.forename: Jiping
authors.initials: J
authors.lastname: Chen
authors.forename: Chenglin
authors.initials: C
authors.lastname: Sun
authors.forename: Zhengkun
authors.initials: Z
authors.lastname: Yu