title: Diffusion tensor imaging fiber tracking with reliable tracking orientation and flexible step size.
abstract: We propose a method of reliable tracking orientation and flexible step size fiber tracking. A new directional strategy was defined to select one optimal tracking orientation from each directional set, which was based on the single-tensor model and the two-tensor model. The directional set of planar voxels contained three tracking directions: two from the two-tensor model and one from the single-tensor model. The directional set of linear voxels contained only one principal vector. In addition, a flexible step size, rather than fixable step sizes, was implemented to improve the accuracy of fiber tracking. We used two sets of human data to assess the performance of our method; one was from a healthy volunteer and the other from a patient with low-grade glioma. Results verified that our method was superior to the single-tensor Fiber Assignment by Continuous Tracking and the two-tensor eXtended Streamline Tractography for showing detailed images of fiber bundles.
authors.affiliation: Shanghai Medical Instrument College, School of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai 200091, China ; Digital Medical Research Center, Shanghai Medical School, Fudan University/The Key Laboratory of MICCAI of Shanghai, Shanghai 200032, China.
authors.forename: Xufeng
authors.initials: X
authors.lastname: Yao
authors.affiliation: Digital Medical Research Center, Shanghai Medical School, Fudan University/The Key Laboratory of MICCAI of Shanghai, Shanghai 200032, China.
authors.forename: Manning
authors.initials: M
authors.lastname: Wang
authors.affiliation: Digital Medical Research Center, Shanghai Medical School, Fudan University/The Key Laboratory of MICCAI of Shanghai, Shanghai 200032, China.
authors.forename: Xinrong
authors.initials: X
authors.lastname: Chen
authors.affiliation: Shanghai Medical Instrument College, School of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai 200091, China.
authors.forename: Shengdong
authors.initials: S
authors.lastname: Nie
authors.affiliation: Shanghai Medical Instrument College, School of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai 200091, China.
authors.forename: Zhexu
authors.initials: Z
authors.lastname: Li
authors.affiliation: Shanghai Medical Instrument College, School of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai 200091, China.
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Xu
authors.affiliation: Shanghai Medical Instrument College, School of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai 200091, China.
authors.forename: Xuelong
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Digital Medical Research Center, Shanghai Medical School, Fudan University/The Key Laboratory of MICCAI of Shanghai, Shanghai 200032, China.
authors.forename: Zhijian
authors.initials: Z
authors.lastname: Song
keywords: diffusion tensor imaging; fiber bundles; fiber tracking; flexible step size; grants-supported paper; neural regeneration; neuroimaging; neuroregeneration; single-tensor model; tracking orientation; two-tensor model