title: Thermoresponsiveness of copolymers bearing cholic acid pendants induced by complexation with β-cyclodextrin.
abstract: Copolymers of N-alkylacrylamides and methacrylate bearing cholic acid pendant groups were synthesized via radical polymerization. The cholic acid pendant groups of such copolymers can form complexes with β-cyclodextrin, and the effect of complexation on their thermoresponsive properties was studied. The phase transition temperatures (transition from hydrophilic to hydrophobic state) of the copolymers gradually increase with the addition of β-cyclodextrin, due to the complexation of the cholic acid guest with the β-cyclodextrin host. The increase of the phase transition temperature may be reversed by the addition of a competing guest molecule, potassium 1-adamantylcarboxylate. The host-guest complexation provides a straightforward way to vary the thermoresponsive properties of such copolymers.
authors.affiliation: Département de Chimie, Université de Montréal , C.P. 6128, Succursale Centre-ville, Montréal, Quebec H3C 3J7, Canada.
authors.forename: Yong-Guang
authors.initials: YG
authors.lastname: Jia
authors.forename: X X
authors.initials: XX
authors.lastname: Zhu