title: Monitoring somatosensory evoked potentials in spinal cord ischemia-reperfusion injury.
abstract: It remains unclear whether spinal cord ischemia-reperfusion injury caused by ischemia and other non-mechanical factors can be monitored by somatosensory evoked potentials. Therefore, we monitored spinal cord ischemia-reperfusion injury in rabbits using somatosensory evoked potential detection technology. The results showed that the somatosensory evoked potential latency was significantly prolonged and the amplitude significantly reduced until it disappeared during the period of spinal cord ischemia. After reperfusion for 30-180 minutes, the amplitude and latency began to gradually recover; at 360 minutes of reperfusion, the latency showed no significant difference compared with the pre-ischemic value, while the somatosensory evoked potential amplitude in-creased, and severe hindlimb motor dysfunctions were detected. Experimental findings suggest that changes in somatosensory evoked potential latency can reflect the degree of spinal cord ischemic injury, while the amplitude variations are indicators of the late spinal cord reperfusion injury, which provide evidence for the assessment of limb motor function and avoid iatrogenic spinal cord injury.
authors.affiliation: Department of Orthopedic Surgery, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China.
authors.forename: Yiming
authors.initials: Y
authors.lastname: Ji
authors.affiliation: Department of Orthopedic Surgery, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Meng
authors.affiliation: Department of Orthopedic Surgery, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China.
authors.forename: Chenxi
authors.initials: C
authors.lastname: Yuan
authors.affiliation: Department of Orthopedic Surgery, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China.
authors.forename: Huilin
authors.initials: H
authors.lastname: Yang
authors.affiliation: Department of Orthopedic Surgery, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Zou
keywords: abdominal aorta occlusion model; grants-supported paper; histopathology; iatrogenic spinal cord injury; ischemia; latency; neural regeneration; neuroregeneration; reperfusion; somatosensory evoked potentials; spinal cord; spinal cord injury