title: Tranexamic acid and fibrinogen restore clotting in vitro and in vivo in cardiac thrombus associated hyperfibrinolysis with overt bleedings.
authors.forename: Michael
authors.initials: M
authors.lastname: Schwameis
authors.forename: Johannes
authors.initials: J
authors.lastname: Thaler
authors.forename: Andreas
authors.initials: A
authors.lastname: Schober
authors.forename: Christian
authors.initials: C
authors.lastname: Schörgenhofer
authors.forename: Christiane
authors.initials: C
authors.lastname: Kulinna-Cosentini
authors.forename: Anton
authors.initials: A
authors.lastname: Laggner
authors.forename: Martin
authors.initials: M
authors.lastname: Röggla
authors.affiliation: Bernd Jilma, MD, Department of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, A-1090 Vienna, Austria, Tel.: +43 1 40400 2981, Fax: +43 1 40400 2998, E-mail: bernd.jilma@meduniwien.ac.at.
authors.forename: Bernd
authors.initials: B
authors.lastname: Jilma
mesh_terms: D000230:Adenocarcinoma / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000556:secondary; D000368:Aged; D000740:Anemia / Q000188:drug therapy / Q000209:etiology / Q000628:therapy; D000933:Antifibrinolytic Agents / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D001777:Blood Coagulation / Q000187:drug effects*; D002294:Carcinoma, Squamous Cell / Q000097:blood / Q000150:complications / Q000556:secondary / Q000601:surgery; D002430:Cecal Neoplasms / Q000097:blood / Q000150:complications / Q000175:diagnosis; D004211:Disseminated Intravascular Coagulation / Q000188:drug therapy* / Q000209:etiology; D017809:Fatal Outcome; D005260:Female; D005340:Fibrinogen / Q000494:pharmacology / Q000627:therapeutic use*; D005342:Fibrinolysis; D005472:Fluorouracil / Q000008:administration & dosage; D006331:Heart Diseases; D006470:Hemorrhage / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008175:Lung Neoplasms / Q000097:blood / Q000556:secondary; D008207:Lymphatic Metastasis / Q000175:diagnosis; D009102:Multiple Organ Failure / Q000209:etiology; D009378:Neoplasms, Multiple Primary / Q000097:blood / Q000150:complications / Q000175:diagnosis; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D011183:Postoperative Complications / Q000188:drug therapy / Q000209:etiology; D013927:Thrombosis; D014148:Tranexamic Acid / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D014846:Vulvar Neoplasms / Q000097:blood / Q000150:complications / Q000601:surgery
chemical_list: D000933:Antifibrinolytic Agents; D009944:Organoplatinum Compounds; D014148:Tranexamic Acid; D005340:Fibrinogen; D002955:Leucovorin; D005472:Fluorouracil