title: Hospitalization cost per case of neonatal herpes simplex virus infection from claims data.
abstract: The purpose of this study was to estimate the average excess inpatient cost of neonatal herpes simplex virus (NHSV) infection from 2005 to 2009 insurance claims data. The estimated adjusted average excess inpatient cost for neonate admissions with HSV diagnosis and >7 days of hospitalization was $40,044 [95% confidence interval (CI), $33,529-$47,775]. When disaggregated by the days of admission, cost estimates were: 8-13 days, $23,918 [CI, $19,490-$29,282]; 14-21 days, $44,358 [CI, $34,654-$56,673]; >21 days, $68,916 [CI, $49,905-$94,967]). Although these estimates are not representative of the entire US, they can inform future economic evaluation studies on NHSV interventions.
authors.affiliation: Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA. Electronic address: Kowusuedusei@cdc.gov.
authors.forename: Kwame
authors.initials: K
authors.lastname: Owusu-Edusei
authors.affiliation: Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
authors.forename: Elaine W
authors.initials: EW
authors.lastname: Flagg
authors.affiliation: Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
authors.forename: Thomas L
authors.initials: TL
authors.lastname: Gift
mesh_terms: D000998:Antiviral Agents / Q000191:economics* / Q000627:therapeutic use; D015331:Cohort Studies; D005260:Female; D017048:Health Care Costs; D006561:Herpes Simplex / Q000175:diagnosis / Q000188:drug therapy* / Q000191:economics*; D006760:Hospitalization / Q000191:economics* / Q000706:statistics & numerical data; D006801:Humans; D007231:Infant, Newborn; D007297:Inpatients / Q000706:statistics & numerical data; D007345:Insurance Claim Review; D007902:Length of Stay / Q000191:economics; D008297:Male; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000188:drug therapy* / Q000191:economics*; D012189:Retrospective Studies; D014481:United States
chemical_list: D000998:Antiviral Agents
keywords: Herpes simplex virus; Inpatient cost; Insured population; Neonates