title: Biofunctionalization of multiwalled carbon nanotubes by electropolymerized poly(pyrrole-concanavalin A) films.
abstract: The synthesis and electropolymerization of a pyrrolic concanavalin A derivative (pyrrole-Con A) onto a multiwalled carbon nanotube (MWCNT) deposit is reported. Glucose oxidase was then immobilized onto the MWCNT-poly(pyrrole-Con A) coating by affinity carbohydrate interactions with the polymerized Con A protein. The resulting enzyme electrode was applied to the amperometric detection of glucose exhibiting a high sensitivity of 36 mA cm(-2) mol(-1) L and a maximum current density of 350 μA cm(-2) .
authors.affiliation: NRF CREATE, Research Wing #02-06, Nanyang Technological University, Singapore 138602 (Singapore).
authors.forename: Vladislav
authors.initials: V
authors.lastname: Papper
authors.forename: Kamal
authors.initials: K
authors.lastname: Elouarzaki
authors.forename: Karine
authors.initials: K
authors.lastname: Gorgy
authors.forename: Ayrine
authors.initials: A
authors.lastname: Sukharaharja
authors.forename: Serge
authors.initials: S
authors.lastname: Cosnier
authors.forename: Robert S
authors.initials: RS
authors.lastname: Marks
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D003208:Concanavalin A / Q000737:chemistry*; D004800:Enzymes, Immobilized / Q000737:chemistry; D005947:Glucose / Q000032:analysis*; D005949:Glucose Oxidase / Q000737:chemistry; D057230:Limit of Detection; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure; D058105:Polymerization; D011108:Polymers / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry*
chemical_list: D004800:Enzymes, Immobilized; D037742:Nanotubes, Carbon; D011108:Polymers; D011758:Pyrroles; D003208:Concanavalin A; C067635:polypyrrole; D005949:Glucose Oxidase; D005947:Glucose
keywords: biofunctionalization; biosensors; carbon nanotubes; concanavalin A; enzymes