title: Allogeneic bone marrow transplantation in a patient with primary hepatic diffuse large B-cell lymphoma that relapsed after autologous stem cell transplantation.
abstract: A 64-year-old woman was admitted to our hospital due to a relapse of primary hepatic lymphoma (PHL). Three years previously, she had been referred to our hospital with a history of chronic hepatitis B for further examination of severe liver dysfunction, at which point a liver biopsy revealed PHL. She received conventional chemotherapy resulting in complete response (CR). An autologous stem cell transplantation was subsequently performed. However, 25 months after the transplantation, she suffered a relapse of PHL and was readmitted to our hospital. She achieved CR after treatment with salvage chemotherapy and then received an allogeneic bone marrow transplantation. CR has since been maintained for more than one year. This case provides insight about treatment choices in PHL.
authors.affiliation: Department of Gastroenterology, Rheumatology, and Clinical Immunology, Sapporo Medical University School of Medicine.
authors.forename: Kazuya
authors.initials: K
authors.lastname: Ishiguro
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Hayashi
authors.forename: Yuka
authors.initials: Y
authors.lastname: Aoki
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Maruyama
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ikeda
authors.forename: Tadao
authors.initials: T
authors.lastname: Ishida
authors.forename: Yasuhisa
authors.initials: Y
authors.lastname: Shinomura