title: Lymphangiomatosis with dental involvement.
abstract: BACKGROUND
  Lymphangiomatosis characterized by lymphangiomatous proliferation is a rare disease of unknown etiology, which seems to be more aggressive than Gorham-Stout Syndrome, also known as "the vanished bone disease."
  
  
  RESULTS
  A woman presented with a lytic lesion in the tibia and multiple lytic lesions in teeth dentin. Upon autopsy, a single lytic bone lesion and fulminant lymphangiomatous proliferation were found in the pleura, pericardium, and peritoneum. The histological findings from a tooth lytic lesion included fibroblastic proliferation interspersed with vascular spaces embedded with fragments of lamellar bone and dentin containing osteoclast like multinucleated giant-cell lined resorption bays.
  
  
  CONCLUSIONS
  The histological findings support the notion that hard tissue resorption is conducted by lymphangiomatosis and osteoclastic activity.
authors.affiliation: 1 Department of Hospital Oral Medicine, Hebrew University Hadassah , Faculty of Dental Medicine, Hebrew University, Jerusalem, Israel .
authors.forename: Mordechai
authors.initials: M
authors.lastname: Findler
authors.forename: Avraham
authors.initials: A
authors.lastname: Hirshberg
authors.forename: Elad
authors.initials: E
authors.lastname: Sharon
mesh_terms: D001706:Biopsy; D005260:Female; D006801:Humans; D018192:Lymphangioleiomyomatosis / Q000175:diagnosis*; D008875:Middle Aged; D011861:Radiography, Dental; D014076:Tooth Diseases / Q000175:diagnosis*