title: Biomarkers in cardiorenal syndrome.
abstract: Cardiac and renal diseases often coexist. Treatment may prove difficult as early diagnosis and effective therapy may be hindered by a lack of robust markers of disease activity. However, several candidate molecules are now available which may help elucidate the complexities of organ cross-talk, enabling effective therapies. We discuss the available data on the commonly studied biomarkers of acute kidney injury with reference to the cardiorenal syndrome. Furthermore, we propose how the use of biomarkers as a panel may provide information which can guide therapy. Although this is a relatively new field, advances are rapid, and such options may well be available to the clinician soon.
authors.affiliation: Department of Critical Care, Western Sussex Hospitals Foundation Trust, Worthing, UK.
authors.forename: Lui G
authors.initials: LG
authors.lastname: Forni
authors.forename: Lakhmir S
authors.initials: LS
authors.lastname: Chawla
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000378:metabolism; D015415:Biomarkers; D059347:Cardio-Renal Syndrome / Q000175:diagnosis / Q000378:metabolism* / Q000628:therapy; D019468:Disease Management; D006801:Humans; D017063:Outcome Assessment, Health Care
chemical_list: D015415:Biomarkers