title: Synchronous gastric gastrointestinal stromal tumor and colon adenocarcinoma: a case report.
abstract: Gastrointestinal stromal tumors (GISTs) represent the majority of primary mesenchymal tumors of the gastrointestinal tract. They are generally considered to be solitary tumors and therefore the synchronous occurrence with other primary malignancies of gastrointestinal track is considered a rare event. Here we present the case of a 75-year-old man admitted to our hospital with a 10-day history of gastrointestinal bleeding. Colonoscopy revealed an ulcerative mass of 4 cm in diameter in the ascending colon. Gastroscopy revealed a bulge in the gastric body measuring 1 cm in diameter with normal overlying mucosa. Surgical intervention was suggested and ileohemicolectomy with regional lymph node resection along with gastric wedge resection was performed. Pathologic examination of the ascending colon mass showed an invasive moderately differentiated adenocarcinoma stage III B (T3N1M0). Grossly resected wedge of stomach showed a well circumscribed intramural tumor which microscopically was consistent with essentially benign gastrointestinal stromal tumor (according to Miettinen criteria). The patient did not receive additional treatment. Two years later the patient showed no evidence of recurrence or metastasis.
authors.affiliation: Department of Pathology, "Tzaneion" General Hospital of Piraeus, 1 Afendouli Avenue, 18536 Piraeus, Greece.
authors.forename: Thivi
authors.initials: T
authors.lastname: Vasilakaki
authors.affiliation: Department of Pathology, "Tzaneion" General Hospital of Piraeus, 1 Afendouli Avenue, 18536 Piraeus, Greece.
authors.forename: Kalliroi
authors.initials: K
authors.lastname: Koulia
authors.affiliation: Department of Pathology, "Tzaneion" General Hospital of Piraeus, 1 Afendouli Avenue, 18536 Piraeus, Greece.
authors.forename: Aikaterini
authors.initials: A
authors.lastname: Tsavari
authors.affiliation: Department of Pathology, "Tzaneion" General Hospital of Piraeus, 1 Afendouli Avenue, 18536 Piraeus, Greece.
authors.forename: Elissavet
authors.initials: E
authors.lastname: Arkoumani
authors.affiliation: Department of Surgery, "Tzaneion" General Hospital of Piraeus, 1 Afendouli Avenue, 18536 Piraeus, Greece.
authors.forename: Efstratios
authors.initials: E
authors.lastname: Kouroumpas
authors.affiliation: Department of Surgery, "Tzaneion" General Hospital of Piraeus, 1 Afendouli Avenue, 18536 Piraeus, Greece.
authors.forename: Anargiros
authors.initials: A
authors.lastname: Pavlis
authors.affiliation: Department of Surgery, "Tzaneion" General Hospital of Piraeus, 1 Afendouli Avenue, 18536 Piraeus, Greece.
authors.forename: Georgios
authors.initials: G
authors.lastname: Christopoulos
authors.affiliation: Department of Surgery, "Tzaneion" General Hospital of Piraeus, 1 Afendouli Avenue, 18536 Piraeus, Greece.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Stamatiou
authors.affiliation: Department of Pathology, "Tzaneion" General Hospital of Piraeus, 1 Afendouli Avenue, 18536 Piraeus, Greece.
authors.forename: Kassiani
authors.initials: K
authors.lastname: Manoloudaki
authors.affiliation: Department of Gastroenterology, "Tzaneion" General Hospital of Piraeus, 1 Afendouli Avenue, 18536 Piraeus, Greece.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Zisis