title: Aneurysmal subarachnoid hemorrhage: a statewide assessment of outcome based on risk factors, aneurysm characteristics, and geo-demography.
abstract: OBJECTIVE
  Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating illness with nationwide mortality rates reaching almost 50% within the first 30 days. A study was undertaken to evaluate how treatment modality, physical findings, and geo-demography contribute to the outcome of these cases, including complications and disposition status.
  
  
  METHODS
  All cases of aSAH in the fiscal year of 2012 (July 2011-June 2012) at the Medical University of South Carolina and Palmetto Health Richland were studied. These healthcare facilities represent 88.5% of aneurysm treatment in the state of South Carolina. Information including aneurysm properties, Hunt-Hess grade, Fisher grade, and symptoms occurring at and after admission were analyzed.
  
  
  RESULTS
  131 patients (94 women and 37 men) with aSAH were treated. 92.4% of cases were treated endovascularly, with more than a third of all cases using balloon-assisted coiling. Hypertension, tobacco use, and hyperlipidemia were the most prevalent comorbidities. Headache, followed by hydrocephalus, motor disturbance, and nausea/vomiting were the most common presenting symptoms. The most common adverse event occurring after hospital admission was acute respiratory failure followed by urinary tract infection, hydrocephalus, and vasospasm. 42.0% were discharged home and nine patients (6.9%) died during hospitalization.
  
  
  CONCLUSIONS
  Previously established risk factors such as hypertension and smoking were identified as the most prevalent comorbidities, with disparity between subgroups, particularly women and African Americans. Endovascular treatment was the primary modality of treatment. Mortality rates were lower than previously reported.
authors.affiliation: Departments of Neurosurgery and Radiology, Medical University of South Carolina, Charleston, South Carolina, USA.
authors.forename: Thomas
authors.initials: T
authors.lastname: Larrew
authors.affiliation: Departments of Neurosurgery and Radiology, Medical University of South Carolina, Charleston, South Carolina, USA.
authors.forename: Will
authors.initials: W
authors.lastname: Pryor
authors.affiliation: Department of Neurosurgery, Palmetto Health, Columbia, South Carolina, USA.
authors.forename: James
authors.initials: J
authors.lastname: Weinberg
authors.affiliation: Department of Neurosurgery, Palmetto Health, Columbia, South Carolina, USA.
authors.forename: Sharon
authors.initials: S
authors.lastname: Webb
authors.affiliation: Department of Public Health Sciences, Medical University of South Carolina, Charleston, South Carolina, USA.
authors.forename: H
authors.initials: H
authors.lastname: Battenhouse
authors.affiliation: Departments of Neurosurgery and Radiology, Medical University of South Carolina, Charleston, South Carolina, USA.
authors.forename: Aquilla S
authors.initials: AS
authors.lastname: Turk
authors.affiliation: Departments of Neurosurgery and Radiology, Medical University of South Carolina, Charleston, South Carolina, USA.
authors.forename: Imran
authors.initials: I
authors.lastname: Chaudry
authors.affiliation: Departments of Neurosurgery and Radiology, Medical University of South Carolina, Charleston, South Carolina, USA.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Spiotta
authors.affiliation: Departments of Neurosurgery and Radiology, Medical University of South Carolina, Charleston, South Carolina, USA.
authors.forename: Raymond
authors.initials: R
authors.lastname: Turner
mesh_terms: D001741:Black or African American / Q000208:ethnology; D017542:Aneurysm, Ruptured / Q000150:complications / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D012307:Risk Factors; D012720:Severity of Illness Index; D012737:Sex Factors; D012959:Socioeconomic Factors; D013022:South Carolina / Q000453:epidemiology; D013345:Subarachnoid Hemorrhage / Q000453:epidemiology / Q000401:mortality / Q000473:pathology / Q000628:therapy
keywords: Aneurysm; Brain; Economics; History; Statistics