title: Postpartum Treatment With Immunoglobulin Does Not Prevent Relapses of Multiple Sclerosis in the Mother.
abstract: Multiple sclerosis (MS) is a chronic, neurological, immune-mediated disease that can worsen in the postpartum period. There is no consensus on the use of immunoglobulin for prevention of disease relapses after delivery. We have shown that the controversial beneficial effect of immunoglobulin given immediately after birth could not be observed in patients with MS.
authors.affiliation: a Department of Neurology, Medical School, Universidade Metropolitana de Santos , , Santos , Brazil.
authors.forename: Yara Dadalti
authors.initials: YD
authors.lastname: Fragoso
authors.affiliation: b Department of Neurology, Hospital Sirio Libanes , Sao Paulo , Brazil.
authors.forename: Tarso
authors.initials: T
authors.lastname: Adoni
authors.affiliation: c Department of Neurology, Universidade Federal do Rio de Janeiro , Rio de Janeiro , Brazil.
authors.forename: Soniza Vieira
authors.initials: SV
authors.lastname: Alves-Leon
authors.affiliation: d Neurology and Neurosurgery Passo Fundo , Passo Fundo , Brazil.
authors.forename: Nerio Dutra
authors.initials: ND
authors.lastname: Azambuja
authors.affiliation: e Department of Neurology, Universidade de São Paulo , Ribeirão Preto , Brazil.
authors.forename: Amilton Antunes
authors.initials: AA
authors.lastname: Barreira
authors.affiliation: f Department of Neurology, Universidade Metropolitana de Santos , Santos , Brazil.
authors.forename: Joseph Bruno Bidin
authors.initials: JB
authors.lastname: Brooks
authors.affiliation: g Department of Neurology, Universidade Federal de Goias , Goiania , Brazil.
authors.forename: Denise Sisteroli Diniz
authors.initials: DS
authors.lastname: Carneiro
authors.affiliation: h Department of Neurology, Fundacao ABC , Santo Andre , Brazil.
authors.forename: Margarete J
authors.initials: MJ
authors.lastname: Carvalho
authors.affiliation: i Department of Neurology, Universidade Federal de Santa Catarina , Florianopolis , Brazil.
authors.forename: Rinaldo
authors.initials: R
authors.lastname: Claudino
authors.affiliation: j Department of Neurology, Universidade Federal de Minas Gerais , Belo Horizonte , Brazil.
authors.forename: Elizabeth Regina
authors.initials: ER
authors.lastname: Comini-Frota
authors.affiliation: k Department of Neurology, Health Sciences School, Santa Casa de Vitoria , Vitoria , Brazil.
authors.forename: Renan Barros
authors.initials: RB
authors.lastname: Domingues
authors.affiliation: l Department of Neurology, Hospital de Clinicas de Porto Alegre , Porto Alegre , Brazil.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Finkelsztejn
authors.affiliation: m Department of Neurology, Pontificia Universidade Catolica Campus Sorocaba , Sorocaba , Brazil.
authors.forename: Paulo Diniz
authors.initials: PD
authors.lastname: Gama
authors.affiliation: n Neurology Clinic , Sao Paulo , Brazil.
authors.forename: Maria Cristina Brandao
authors.initials: MC
authors.lastname: Giacomo
authors.affiliation: o Department of Neurology, Hospital Beneficencia Portuguesa and Hospital Paulistano , Sao Paulo , Brazil.
authors.forename: Sidney
authors.initials: S
authors.lastname: Gomes
authors.affiliation: p Department of Neurology, Universidade da Regiao de Joinville , Joinville , Brazil.
authors.forename: Marcus Vinicius Magno
authors.initials: MV
authors.lastname: Goncalves
authors.affiliation: q Department of Neurology, Rehabilitation Center Dom Aquino Correa , Cuiaba , Brazil.
authors.forename: Anderson Kuntz
authors.initials: AK
authors.lastname: Grzesiuk
authors.affiliation: r Department of Neurology, Universidade Estadual de Londrina , Londrina , Brazil.
authors.forename: Damacio Ramon
authors.initials: DR
authors.lastname: Kaimen-Maciel
authors.affiliation: s Department of Neurology, Santa Casa de Sao Paulo , Sao Paulo , Brazil.
authors.forename: Maria Fernanda
authors.initials: MF
authors.lastname: Mendes
authors.affiliation: t Department of Neurology, Universidade Federal de Uberlandia , Uberlandia , Brazil.
authors.forename: Nivea Macedo Oliveira
authors.initials: NM
authors.lastname: Morales
authors.affiliation: t Department of Neurology, Universidade Federal de Uberlandia , Uberlandia , Brazil.
authors.forename: Rogerio Rizo
authors.initials: RR
authors.lastname: Morales
authors.affiliation: u Department of Neurology, Hospital Sao Rafael , Salvador , Brazil.
authors.forename: Andre
authors.initials: A
authors.lastname: Muniz
authors.affiliation: v Department of Neurology, Universidade Federal do Estado do Rio de Janeiro , Rio de Janeiro , Brazil.
authors.forename: Regina Maria
authors.initials: RM
authors.lastname: Papais-Alvarenga
authors.affiliation: w Neurology Clinic , Curitiba , Brazil.
authors.forename: Monica Koncke Fiuza
authors.initials: MK
authors.lastname: Parolin
authors.affiliation: x Department of Neurology, Universidade Federal do Triangulo Mineiro , Uberaba , Brazil.
authors.forename: Sonia Beatriz Felix
authors.initials: SB
authors.lastname: Ribeiro
authors.affiliation: y Department of Neurology, MS Center Jundiai , Jundiai , Brazil.
authors.forename: Heloisa Helena
authors.initials: HH
authors.lastname: Ruocco
authors.affiliation: z Department of Neurology, Universidade Federal de Mato Grosso do Sul , Campo Grande , Brazil.
authors.forename: Pedro Rippel
authors.initials: PR
authors.lastname: Salgado
authors.affiliation: aa Department of Neurology, Universidade Regional de Blumenau , Blumenau , Brazil.
authors.forename: Fabio
authors.initials: F
authors.lastname: Siquineli
authors.affiliation: e Department of Neurology, Universidade de São Paulo , Ribeirão Preto , Brazil.
authors.forename: Doralina Brum
authors.initials: DB
authors.lastname: Souza
authors.affiliation: ab Department of Neurology, Hospital de Base do Distrito Federal , Brasilia , Brazil.
authors.forename: Elza Dias
authors.initials: ED
authors.lastname: Tosta
authors.affiliation: v Department of Neurology, Universidade Federal do Estado do Rio de Janeiro , Rio de Janeiro , Brazil.
authors.forename: Claudia Cristina Ferreira
authors.initials: CC
authors.lastname: Vasconcelos
authors.affiliation: c Department of Neurology, Universidade Federal do Rio de Janeiro , Rio de Janeiro , Brazil.
authors.forename: Sandra Maria Garcia
authors.initials: SM
authors.lastname: Almeida
authors.affiliation: u Department of Neurology, Hospital Sao Rafael , Salvador , Brazil.
authors.forename: Daniella Freire Ribeiro
authors.initials: DF
authors.lastname: Bernardes
authors.affiliation: z Department of Neurology, Universidade Federal de Mato Grosso do Sul , Campo Grande , Brazil.
authors.forename: Simone Nascimento
authors.initials: SN
authors.lastname: Castro
authors.affiliation: m Department of Neurology, Pontificia Universidade Catolica Campus Sorocaba , Sorocaba , Brazil.
authors.forename: Rodrigo Assad Diniz
authors.initials: RA
authors.lastname: Gama
authors.affiliation: x Department of Neurology, Universidade Federal do Triangulo Mineiro , Uberaba , Brazil.
authors.forename: Fabrizio Antonio Resende
authors.initials: FA
authors.lastname: Gomide
authors.affiliation: l Department of Neurology, Hospital de Clinicas de Porto Alegre , Porto Alegre , Brazil.
authors.forename: Juliana
authors.initials: J
authors.lastname: Finkelzstejn
authors.affiliation: r Department of Neurology, Universidade Estadual de Londrina , Londrina , Brazil.
authors.forename: Josiane
authors.initials: J
authors.lastname: Lopes
authors.affiliation: z Department of Neurology, Universidade Federal de Mato Grosso do Sul , Campo Grande , Brazil.
authors.forename: Fabiani Honorato de Barros
authors.initials: FH
authors.lastname: Lourenco
authors.affiliation: c Department of Neurology, Universidade Federal do Rio de Janeiro , Rio de Janeiro , Brazil.
authors.forename: Gisele A
authors.initials: GA
authors.lastname: Lourenco
authors.affiliation: f Department of Neurology, Universidade Metropolitana de Santos , Santos , Brazil.
authors.forename: Celso Luis Silva
authors.initials: CL
authors.lastname: Oliveira
authors.affiliation: o Department of Neurology, Hospital Beneficencia Portuguesa and Hospital Paulistano , Sao Paulo , Brazil.
authors.forename: Francisco Tomaz Meneses
authors.initials: FT
authors.lastname: Oliveira
authors.affiliation: x Department of Neurology, Universidade Federal do Triangulo Mineiro , Uberaba , Brazil.
authors.forename: Lucas Felix
authors.initials: LF
authors.lastname: Oliveira
authors.affiliation: c Department of Neurology, Universidade Federal do Rio de Janeiro , Rio de Janeiro , Brazil.
authors.forename: Cristiane Borges
authors.initials: CB
authors.lastname: Patroclo
authors.affiliation: r Department of Neurology, Universidade Estadual de Londrina , Londrina , Brazil.
authors.forename: Wildea Lice de Carvalho Jennings
authors.initials: WL
authors.lastname: Pereira
authors.affiliation: p Department of Neurology, Universidade da Regiao de Joinville , Joinville , Brazil.
authors.forename: Juliana
authors.initials: J
authors.lastname: Safanelli
authors.affiliation: ab Department of Neurology, Hospital de Base do Distrito Federal , Brasilia , Brazil.
authors.forename: Alinne Martiniano
authors.initials: AM
authors.lastname: Sahdo
authors.affiliation: k Department of Neurology, Health Sciences School, Santa Casa de Vitoria , Vitoria , Brazil.
authors.forename: Patricia Correa de Oliveira
authors.initials: PC
authors.lastname: Saldanha
authors.affiliation: m Department of Neurology, Pontificia Universidade Catolica Campus Sorocaba , Sorocaba , Brazil.
authors.forename: Yves Fumio
authors.initials: YF
authors.lastname: Shinzato
authors.affiliation: i Department of Neurology, Universidade Federal de Santa Catarina , Florianopolis , Brazil.
authors.forename: Jorge Murilo Barbosa
authors.initials: JM
authors.lastname: Souza
authors.affiliation: m Department of Neurology, Pontificia Universidade Catolica Campus Sorocaba , Sorocaba , Brazil.
authors.forename: Denis Evandro
authors.initials: DE
authors.lastname: Zani
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000494:pharmacology / Q000627:therapeutic use*; D009035:Mothers; D009103:Multiple Sclerosis / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000517:prevention & control*; D049590:Postpartum Period / Q000187:drug effects*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy / Q000276:immunology; D011256:Pregnancy Outcome; D011644:Puerperal Disorders / Q000517:prevention & control; D012008:Recurrence; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D016756:Immunoglobulins, Intravenous