title: Value of classical criteria for diagnosis of cardiac amyloidosis re-evaluated with magnetic resonance.
abstract: The noninvasive diagnosis of cardiac amyloidosis (CA) is often challenging. ECG abnormalities are common but lack both sensitivity and specificity. While some features on transthoracic echocardiography have confirmed the classical picture of CA, they have generally been validated against endomyocardial biopsy and thus are indicative of advanced disease. The ability of cardiac magnetic resonance to characterize the myocardium has opened a new door in the noninvasive diagnosis of CA, representing an opportunity to revisit the role of traditional ECG and transthoracic echocardiography diagnostic crtieria in earlier disease stages.
authors.affiliation: The Zena and Michael A. Wiener Cardiovascular Institute/Marie-Josee and Henry R. Kravis Center for Cardiovascular Health, Icahn School of Medicine, New York, NY, USA.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Pozo
authors.forename: Javier
authors.initials: J
authors.lastname: Sanz
mesh_terms: D000686:Amyloidosis / Q000175:diagnosis* / Q000473:pathology; D009202:Cardiomyopathies / Q000175:diagnosis*; D004452:Echocardiography / Q000379:methods; D004562:Electrocardiography / Q000379:methods; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D012680:Sensitivity and Specificity
keywords: cardiac amyloidosis; cardiac magnetic resonance; diagnosis; echocardiography; electrocardiography