title: Biosynthesis of fungal indole alkaloids.
abstract: This review provides a summary of recent research advances in elucidating the biosynthesis of fungal indole alkaloids. The different strategies used to incorporate and derivatize the indole/indoline moieties in various families of fungal indole alkaloids will be discussed, including tryptophan-containing nonribosomal peptides, polyketide-nonribosomal peptide hybrids, and alkaloids derived from other indole building blocks. This review also includes a discussion regarding the downstream modifications that generate chemical and structural diversity among indole alkaloids.
authors.affiliation: Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, 420 Westwood Plaza, Los Angeles, CA 90096, USA. yitang@ucla.edu.
authors.forename: Wei
authors.initials: W
authors.lastname: Xu
authors.forename: Diego J
authors.initials: DJ
authors.lastname: Gavia
authors.forename: Yi
authors.initials: Y
authors.lastname: Tang
mesh_terms: D005658:Fungi / Q000737:chemistry / Q000378:metabolism; D026121:Indole Alkaloids / Q000737:chemistry / Q000378:metabolism; D015394:Molecular Structure
chemical_list: D026121:Indole Alkaloids