title: Integrated signaling networks in plant responses to sedentary endoparasitic nematodes: a perspective.
abstract: Sedentary plant endoparasitic nematodes can cause detrimental yield losses in crop plants making the study of detailed cellular, molecular, and whole plant responses to them a subject of importance. In response to invading nematodes and nematode-secreted effectors, plant susceptibility/resistance is mainly determined by the coordination of different signaling pathways including specific plant resistance genes or proteins, plant hormone synthesis and signaling pathways, as well as reactive oxygen signals that are generated in response to nematode attack. Crosstalk between various nematode resistance-related elements can be seen as an integrated signaling network regulated by transcription factors and small RNAs at the transcriptional, posttranscriptional, and/or translational levels. Ultimately, the outcome of this highly controlled signaling network determines the host plant susceptibility/resistance to nematodes.
authors.affiliation: Department of Biological Sciences, Auburn University, 101 Rouse Life Science Building, Auburn, AL, 36849, USA.
authors.forename: Ruijuan
authors.initials: R
authors.lastname: Li
authors.forename: Aaron M
authors.initials: AM
authors.lastname: Rashotte
authors.forename: Narendra K
authors.initials: NK
authors.lastname: Singh
authors.forename: David B
authors.initials: DB
authors.lastname: Weaver
authors.forename: Kathy S
authors.initials: KS
authors.lastname: Lawrence
authors.forename: Robert D
authors.initials: RD
authors.lastname: Locy
mesh_terms: D000818:Animals; D060467:Disease Resistance / Q000235:genetics / Q000276:immunology; D018506:Gene Expression Regulation, Plant / Q000235:genetics / Q000276:immunology*; D006790:Host-Parasite Interactions / Q000276:immunology; D018448:Models, Immunological; D009348:Nematoda / Q000276:immunology* / Q000502:physiology; D010935:Plant Diseases / Q000235:genetics / Q000276:immunology / Q000469:parasitology; D010940:Plant Proteins / Q000235:genetics / Q000276:immunology / Q000378:metabolism; D010944:Plants / Q000235:genetics / Q000276:immunology* / Q000469:parasitology; D015398:Signal Transduction / Q000235:genetics / Q000276:immunology*
chemical_list: D010940:Plant Proteins