title: Crossed cerebellar diaschisis detected by arterial spin-labeled perfusion magnetic resonance imaging in subacute ischemic stroke.
abstract: BACKGROUND
  Crossed cerebellar diaschisis (CCD) was a common radiological phenomenon manifested as reduced blood flow and metabolism in the cerebellar hemisphere contralateral to a supratentorial cerebral lesion. The hypoperfusion and hypometabolism in the contralateral cerebellum in CCD was traditionally detected by positron emission tomography (PET) and single-photon emission computed tomography (SPECT). The present prospective study aimed to assess the detection of CCD in subacute stage ischemic stroke by arterial spin-labeling (ASL) perfusion technique with a 3.0-T magnetic resonance imaging (MRI) scanner.
  
  
  METHODS
  ASL images were obtained from 46 patients with supratentorial ischemic stroke at subacute stage. Regional cerebral blood flow values in the cerebellar hemispheres were measured on a region of interest basis.
  
  
  RESULTS
  Twenty-four of 46 (52%) patients showed CCD phenomenon by ASL-MRI method, which was in line with the PET/SPECT series. Infarctions in basal ganglia areas are prone to cause CCD.
  
  
  CONCLUSIONS
  With advantages in easy acquisition and no radiation, ASL-MRI seems to be an ideal tool for the detection and follow-up of CCD.
authors.affiliation: Department of Neurology, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
authors.forename: Shuai
authors.initials: S
authors.lastname: Chen
authors.affiliation: Department of Radiology, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
authors.forename: Min
authors.initials: M
authors.lastname: Guan
authors.affiliation: Department of Neurology, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
authors.forename: Hao-Jun
authors.initials: HJ
authors.lastname: Lian
authors.affiliation: Department of Radiology, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
authors.forename: Li-Jia
authors.initials: LJ
authors.lastname: Ma
authors.affiliation: Department of Neurology, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
authors.forename: Jun-Kui
authors.initials: JK
authors.lastname: Shang
authors.affiliation: Department of Neurology, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
authors.forename: Shuang
authors.initials: S
authors.lastname: He
authors.affiliation: Department of Neurology, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
authors.forename: Ming-Ming
authors.initials: MM
authors.lastname: Ma
authors.affiliation: Department of Neurology, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
authors.forename: Mi-Lan
authors.initials: ML
authors.lastname: Zhang
authors.affiliation: Department of Radiology, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
authors.forename: Zi-Yuan
authors.initials: ZY
authors.lastname: Li
authors.affiliation: Department of Radiology, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
authors.forename: Mei-Yun
authors.initials: MY
authors.lastname: Wang
authors.affiliation: Department of Radiology, Zhengzhou University People's Hospital, Zhengzhou, Henan, China. Electronic address: cjr.shidapeng@vip.163.com.
authors.forename: Da-Peng
authors.initials: DP
authors.lastname: Shi
authors.affiliation: Department of Neurology, Zhengzhou University People's Hospital, Zhengzhou, Henan, China. Electronic address: zhangjw9900@126.com.
authors.forename: Jie-Wen
authors.initials: JW
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D002545:Brain Ischemia / Q000150:complications / Q000473:pathology*; D002526:Cerebellar Diseases / Q000209:etiology / Q000473:pathology*; D002531:Cerebellum / Q000473:pathology; D002560:Cerebrovascular Circulation; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013113:Spin Labels; D020521:Stroke / Q000150:complications / Q000473:pathology*
chemical_list: D013113:Spin Labels
keywords: Crossed cerebellar diaschisis; arterial spin-labeling; magnetic resonance imaging; stroke