title: Central retinal artery occlusion with concomitant ipsilateral cerebral infarction after cosmetic facial injections.
abstract: We report 2 cases of central retinal artery occlusion with concomitant ipsilateral cerebral infarction after cosmetic facial injections and a literature review. The 2 patients were two healthy women, in which cosmetic facial injections with autologous fat and filler were performed, respectively. The patients had no light perception at the final visit and their conditions led to memory retrieval disturbance in case 1 and right arm weakness, dysarthria, facial palsy, and ophthalmoplegia in case 2. Neuroimaging showed multifocal small infarctions in the ipsilateral frontal lobe with occlusion of the ophthalmic artery in case 1 and multiple infarctions in the ipsilateral anterior and middle cerebral artery territories with subsequent hemorrhagic transformation in case 2. Poor visual prognosis and neurological complications can occur in healthy adults undergoing cosmetic facial injection, and all patients should be informed of this risk before the procedure.
authors.affiliation: Department of Neurology, Keimyung University Dongsan Medical Center, Daegu, Republic of Korea.
authors.forename: Jeong-Ho
authors.initials: JH
authors.lastname: Hong
authors.affiliation: Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
authors.forename: Seong Joon
authors.initials: SJ
authors.lastname: Ahn
authors.affiliation: Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
authors.forename: Se Joon
authors.initials: SJ
authors.lastname: Woo
authors.affiliation: Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
authors.forename: Cheolkyu
authors.initials: C
authors.lastname: Jung
authors.affiliation: Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
authors.forename: Jun Young
authors.initials: JY
authors.lastname: Chang
authors.affiliation: Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
authors.forename: Jin-Heon
authors.initials: JH
authors.lastname: Chung
authors.affiliation: Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea. Electronic address: mkhan@snu.ac.kr.
authors.forename: Moon-Ku
authors.initials: MK
authors.lastname: Han
mesh_terms: D000328:Adult; D002544:Cerebral Infarction / Q000209:etiology* / Q000503:physiopathology; D003357:Cosmetic Techniques / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007267:Injections / Q000009:adverse effects*; D008875:Middle Aged; D009460:Neurologic Examination; D009886:Ophthalmoplegia / Q000209:etiology* / Q000503:physiopathology; D015356:Retinal Artery Occlusion / Q000209:etiology* / Q000503:physiopathology
keywords: Autologous fat; Cerebral infarction; Cosmetic; Filler; Ophthalmic artery; Retinal artery occlusion