title: Early glottic cancer: role of MRI in the preoperative staging.
abstract: BACKGROUND
  Clinical staging is the most important time in management of glottic cancer in early stage (I-II). We have conducted a prospective study to evaluate if magnetic resonance imaging (MRI) is more accurate than computed tomography (CT) about tumoral extension, to exactly choose the most appropriate surgical approach, from organ preservation surgery to demolitive surgery. MATERIALS and
  
  
  METHODS
  This prospective study was conducted on 26 male patients, with suspected laryngeal neoplasia of glottic region. The images of MRI and CT were analyzed to define the expansion of glottic lesion to anterior commissure, laryngeal cartilages, subglottic and/or supraglottic site, and paraglottic space. The results of MRI and CT were compared with each other and with the pathology report.
  
  
  RESULTS
  CT accuracy was 70% with low sensitivity but with high specific value. MRI showed a diagnostic accuracy in 80% of cases, with a sensitivity of 100% and high specificity. Statistical analysis showed that MRI has higher correlation than CT with the pathology report.
  
  
  CONCLUSIONS
  Our study showed that MRI is more sensitive than CT in the preoperative staging of early glottic cancer, to select exactly the eligible patients in conservative surgery of the larynx, as supracricoid laryngectomy and cordectomy by CO2 laser.
authors.affiliation: Department of Experimental and Clinical Medicine-Otolaryngology Head and Neck Surgery, University of Catanzaro, Viale Europa, Località Germaneto, 88100 Catanzaro, Italy.
authors.forename: Eugenia
authors.initials: E
authors.lastname: Allegra
authors.affiliation: Department of Experimental and Clinical Medicine-Otolaryngology Head and Neck Surgery, University of Catanzaro, Viale Europa, Località Germaneto, 88100 Catanzaro, Italy.
authors.forename: Pierpaolo
authors.initials: P
authors.lastname: Ferrise
authors.affiliation: Department of Experimental and Clinical Medicine-Otolaryngology Head and Neck Surgery, University of Catanzaro, Viale Europa, Località Germaneto, 88100 Catanzaro, Italy.
authors.forename: Serena
authors.initials: S
authors.lastname: Trapasso
authors.affiliation: Department of Experimental and Clinical Medicine-Radiology, University of Catanzaro, Viale Europa, Località Germaneto, 88100 Catanzaro, Italy.
authors.forename: Orazio
authors.initials: O
authors.lastname: Trapuzzano
authors.affiliation: Department of Experimental and Clinical Medicine-Radiology, University of Catanzaro, Viale Europa, Località Germaneto, 88100 Catanzaro, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Barca
authors.affiliation: Department of Radiology, Pellegrini Hospital, 80135 Naples, Italy.
authors.forename: Stefania
authors.initials: S
authors.lastname: Tamburrini
authors.affiliation: Department of Experimental and Clinical Medicine-Otolaryngology Head and Neck Surgery, University of Catanzaro, Viale Europa, Località Germaneto, 88100 Catanzaro, Italy.
authors.forename: Aldo
authors.initials: A
authors.lastname: Garozzo
mesh_terms: D000368:Aged; D006801:Humans; D007822:Laryngeal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011300:Preoperative Care; D013223:Statistics as Topic; D014057:Tomography, X-Ray Computed; D014827:Vocal Cords / Q000000981:diagnostic imaging / Q000473:pathology