title: Pediatric surgeons and anesthesiologists expand the dialogue on the neurotoxicity question, rationale for early and delayed surgeries, and practice changes while awaiting definitive evidence.
abstract: The Pediatric Anesthesia NeuroDevelopment Assessment team at Columbia University Medical Center Department of Anesthesiology convened its fourth biennial Symposium to address unresolved issues concerning potential neurotoxic effects of anesthetic agents and sedatives on young children and to assess study findings to date. Dialogue initiated at the third Symposium was continued between anesthesiologists, researchers, and a panel of expert pediatric surgeons representing general surgery and dermatology, orthopedic, and urology specialties. The panel explored the need to balance benefits of early surgery using improved technologies against potential anesthetic risks, practice changes while awaiting definitive answers, and importance of continued interprofessional dialogue.
authors.affiliation: *Department of Anesthesiology, College of Physicians and Surgeons, Columbia University School of Nursing Divisions of †Pediatric Urology ‡Pediatric Dermatology #Pediatric Surgery, Morgan Stanley Children's Hospital §Department of Orthopedic Surgery, New York-Presbyterian Hospital/Columbia University Medical Center, College of Physicians and Surgeons, Columbia University ∥Department of Anesthesiology, New York-Presbyterian Hospital/Columbia University Medical Center ¶NorthShore-LIJ Health System, Hofstra North Shore-LIJ School of Medicine, New York, NY.
authors.forename: Mary W
authors.initials: MW
authors.lastname: Byrne
authors.forename: Pasquale
authors.initials: P
authors.lastname: Casale
authors.forename: Maria
authors.initials: M
authors.lastname: Garzon
authors.forename: Joshua E
authors.initials: JE
authors.lastname: Hyman
authors.forename: Albert Y
authors.initials: AY
authors.lastname: Lin
authors.forename: Lisa R
authors.initials: LR
authors.lastname: Lynch
authors.forename: Charles L
authors.initials: CL
authors.lastname: Schleien
authors.forename: Steven
authors.initials: S
authors.lastname: Stylianos
mesh_terms: D000758:Anesthesia / Q000009:adverse effects*; D000776:Anesthesiology / Q000379:methods*; D000777:Anesthetics / Q000009:adverse effects*; D002648:Child; D006801:Humans; D020258:Neurotoxicity Syndromes / Q000517:prevention & control*; D010372:Pediatrics / Q000379:methods*; D012306:Risk; D066231:Surgeons
chemical_list: D000777:Anesthetics