title: An Improved Process for the Preparation of an α,α-Difluorosulfonylisoxazoline Herbicide.
abstract: An efficient synthesis of a difluorosulfone-containing herbicide has been achieved by selective reductive silylation of a symmetrical bis(trifluoromethyl)-1,2,3-triazole. Subsequently, a fluoride-induced reaction led to a difluoromethyl anion equivalent, which was reacted with a sulfur electrophile leading ultimately to the key difluorosulfide moiety.
authors.affiliation: Syngenta Crop Protection, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK.
authors.forename: Chantal
authors.initials: C
authors.lastname: Belie
authors.affiliation: Syngenta Crop Protection, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK.
authors.forename: Jutta
authors.initials: J
authors.lastname: Boehmer
authors.affiliation: Syngenta Crop Protection, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK.
authors.forename: Eric
authors.initials: E
authors.lastname: Clarke
authors.affiliation: Syngenta Crop Protection, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK.
authors.forename: Anne
authors.initials: A
authors.lastname: Dalençon
authors.affiliation: Syngenta Crop Protection, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Dallimore
authors.affiliation: Syngenta Crop Protection AG, CH-4002 Basel, Switzerland.
authors.forename: Martin
authors.initials: M
authors.lastname: Diggelmann
authors.affiliation: Syngenta Crop Protection Münchwilen AG, Schaffhauserstrasse, CH-4332 Stein, Switzerland. myriem.el_qacemi@syngenta.com.
authors.forename: Myriem El
authors.initials: ME
authors.lastname: Qacemi
authors.affiliation: Syngenta Crop Protection, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK.
authors.forename: Katharine
authors.initials: K
authors.lastname: Ingram
authors.affiliation: Syngenta Crop Protection, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK.
authors.forename: Andy
authors.initials: A
authors.lastname: Knee
authors.affiliation: Syngenta Crop Protection, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK.
authors.forename: Tony
authors.initials: T
authors.lastname: Kozakiewicz
authors.affiliation: Syngenta Crop Protection, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK.
authors.forename: Adrian
authors.initials: A
authors.lastname: Longstaff
authors.affiliation: Syngenta Crop Protection, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK.
authors.forename: Derek
authors.initials: D
authors.lastname: McCormack
authors.affiliation: Syngenta Crop Protection, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK.
authors.forename: Matthew
authors.initials: M
authors.lastname: McLachlan
authors.affiliation: Syngenta Crop Protection, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK.
authors.forename: Nick
authors.initials: N
authors.lastname: Mulholland
authors.affiliation: Syngenta Crop Protection AG, CH-4002 Basel, Switzerland.
authors.forename: Andrew
authors.initials: A
authors.lastname: Plant
authors.affiliation: Syngenta Crop Protection, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK.
authors.forename: John
authors.initials: J
authors.lastname: Williams