title: Cu-catalyzed ring opening reaction of 2H-azirines with terminal alkynes: an easy access to 3-alkynylated pyrroles.
abstract: A highly efficient Cu-catalyzed ring expansion reaction of 2H-azirines with terminal alkynes has been developed. This transformation provides a powerful method for the synthesis of 3-alkynyl polysubstituted pyrroles under mild conditions in good yields. The direct transformation process, specific selectivity, and good tolerance to a variety of substituents make it an alternative approach to the reported protocols.
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences , 457 Zhongshan Road, Dalian 116023, China.
authors.forename: Tengfei
authors.initials: T
authors.lastname: Li
authors.forename: Xiaoyi
authors.initials: X
authors.lastname: Xin
authors.forename: Chunxiang
authors.initials: C
authors.lastname: Wang
authors.forename: Dongping
authors.initials: D
authors.lastname: Wang
authors.forename: Fan
authors.initials: F
authors.lastname: Wu
authors.forename: Xincheng
authors.initials: X
authors.lastname: Li
authors.forename: Boshun
authors.initials: B
authors.lastname: Wan