title: Small bowel adenocarcinoma and Crohn's disease: any further ahead than 50 years ago?
abstract: This review of the literature on small bowel carcinoma associated with Crohn's disease specifically addresses the incidence, risk factors, and protective factors which have been identified. It also reviews the clinical presentation, the current modalities of diagnosis, the pathology, treatment, and surveillance. Finally, the prognosis and future direction are addressed. Our experience with small bowel adenocarcinoma in Crohn's disease is reported. Readers will be provided with a better understanding of this rare and often poorly recognized complication of Crohn's disease.
authors.affiliation: Caitlin Cahill, Philip H Gordon, Andrea Petrucci, Marylise Boutros, McGill University Department of Surgery; Sir Mortimer B. Davis Jewish General Hospital Colorectal Surgery, Montreal PQ H3T 1E2, Canada.
authors.forename: Caitlin
authors.initials: C
authors.lastname: Cahill
authors.affiliation: Caitlin Cahill, Philip H Gordon, Andrea Petrucci, Marylise Boutros, McGill University Department of Surgery; Sir Mortimer B. Davis Jewish General Hospital Colorectal Surgery, Montreal PQ H3T 1E2, Canada.
authors.forename: Philip H
authors.initials: PH
authors.lastname: Gordon
authors.affiliation: Caitlin Cahill, Philip H Gordon, Andrea Petrucci, Marylise Boutros, McGill University Department of Surgery; Sir Mortimer B. Davis Jewish General Hospital Colorectal Surgery, Montreal PQ H3T 1E2, Canada.
authors.forename: Andrea
authors.initials: A
authors.lastname: Petrucci
authors.affiliation: Caitlin Cahill, Philip H Gordon, Andrea Petrucci, Marylise Boutros, McGill University Department of Surgery; Sir Mortimer B. Davis Jewish General Hospital Colorectal Surgery, Montreal PQ H3T 1E2, Canada.
authors.forename: Marylise
authors.initials: M
authors.lastname: Boutros
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D003424:Crohn Disease / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D006801:Humans; D015994:Incidence; D007414:Intestinal Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D007421:Intestine, Small / Q000187:drug effects / Q000473:pathology / Q000601:surgery; D011237:Predictive Value of Tests; D011379:Prognosis; D065840:Protective Factors; D018570:Risk Assessment; D012307:Risk Factors
keywords: Cancer malignancy; Cancer risk; Crohn’s disease; Incidental carcinoma; Inflammatory bowel disease; Late complications of Crohn’s disease; Small bowel adenocarcinoma