title: The role of sweet taste in satiation and satiety.
abstract: Increased energy consumption, especially increased consumption of sweet energy-dense food, is thought to be one of the main contributors to the escalating rates in overweight individuals and obesity globally. The individual's ability to detect or sense sweetness in the oral cavity is thought to be one of many factors influencing food acceptance, and therefore, taste may play an essential role in modulating food acceptance and/or energy intake. Emerging evidence now suggests that the sweet taste signaling mechanisms identified in the oral cavity also operate in the gastrointestinal system and may influence the development of satiety. Understanding the individual differences in detecting sweetness in both the oral and gastrointestinal system towards both caloric sugar and high intensity sweetener and the functional role of the sweet taste system may be important in understanding the reasons for excess energy intake. This review will summarize evidence of possible associations between the sweet taste mechanisms within the oral cavity, gastrointestinal tract and the brain systems towards both caloric sugar and high intensity sweetener and sweet taste function, which may influence satiation, satiety and, perhaps, predisposition to being overweight and obesity.
authors.affiliation: Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences, Deakin University, Burwood, Victoria 3125, Australia. yqlow@deakin.edu.au.
authors.forename: Yu Qing
authors.initials: YQ
authors.lastname: Low
authors.affiliation: Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences, Deakin University, Burwood, Victoria 3125, Australia. katie.lacy@deakin.edu.au.
authors.forename: Kathleen
authors.initials: K
authors.lastname: Lacy
authors.affiliation: Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences, Deakin University, Burwood, Victoria 3125, Australia. russell.keast@deakin.edu.au.
authors.forename: Russell
authors.initials: R
authors.lastname: Keast
mesh_terms: D004032:Diet; D019422:Dietary Sucrose / Q000009:adverse effects; D002149:Energy Intake; D005518:Food Preferences; D041981:Gastrointestinal Tract; D006801:Humans; D009765:Obesity / Q000209:etiology; D012527:Satiation; D012528:Satiety Response; D013549:Sweetening Agents / Q000009:adverse effects; D055697:Taste Perception; D013652:Taste Threshold
chemical_list: D019422:Dietary Sucrose; D013549:Sweetening Agents