title: Educational paper: therapy of infantile haemangioma--history and current state (part II).
abstract: Infantile haemangioma (IH) is the most frequent tumour of infancy. Although it is benign and self-limiting, severe complications can arise due to localisation and fast tumour growth. Also, IHs leave scars after regression in more than half of the cases. Management and therapy of IH have changed greatly after 2008. This update provides an overview of the older therapy options before 2008, which mainly consisted of the administration of corticosteroids, and discusses the modern management with new therapy options such as β-blockers (both systemically and topically).
  
  
  CONCLUSIONS
  β-blockers are promising and are currently preferred above corticosteroids, but β-blockers still do not give a definitive treatment.
authors.affiliation: Department of Dermatology, UZ Brussel, University Medical Centre, Brussels, Belgium, sherief.janmohamed@uzbrussel.be.
authors.forename: Sherief R
authors.initials: SR
authors.lastname: Janmohamed
authors.forename: Gerard C
authors.initials: GC
authors.lastname: Madern
authors.forename: Peter C J
authors.initials: PC
authors.lastname: de Laat
authors.forename: Arnold P
authors.initials: AP
authors.lastname: Oranje
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000634:Aminoquinolines / Q000627:therapeutic use; D005938:Glucocorticoids / Q000627:therapeutic use; D006391:Hemangioma / Q000188:drug therapy* / Q000266:history*; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D000077271:Imiquimod; D007223:Infant; D007231:Infant, Newborn
chemical_list: D000276:Adjuvants, Immunologic; D000319:Adrenergic beta-Antagonists; D000634:Aminoquinolines; D005938:Glucocorticoids; D000077271:Imiquimod