title: The diagnostic accuracy of two- vs three-dimensional sonohysterography for evaluation of the uterine cavity in the reproductive age.
abstract: OBJECTIVE
  To compare 2-dimensional sonohysterography (2D SHG) vs 3-dimensional sonohysterography (3D SHG) using saline solution infusion, with outpatient hysteroscopy as the gold standard, for evaluation of the uterine cavity in women of reproductive age.
  
  
  METHODS
  Comparative observational cross-sectional study (Canadian Task Force classification II-2).
  
  
  METHODS
  University hospital.
  
  
  METHODS
  One hundred twenty women of reproductive age with abnormal uterine bleeding, infertility, or recurrent pregnancy loss and with clinically and/or ultrasongraphically suspected intrauterine lesions.
  
  
  METHODS
  All patients underwent 2D SHG and 3D SHG using saline solution infusion followed by outpatient hysteroscopy. Sonographic findings were compared with hysteroscopic findings.
  
  
  RESULTS
  For 2D SHG, sensitivity was 71.2%; specificity, 94.1%; positive predictive value, 90.2%; negative predictive value, 81.0%; and overall accuracy, 84.2%. For 3D SHG, sensitivity was 94.2%; specificity, 98.5%; positive predictive value, 98.0%; negative predictive value, 95.7%; and overall accuracy, 96.7%. Thus, 3D SHG was superior to 2D SHG (p = .02) and comparable with outpatient hysteroscopy (p = .12) for diagnosis of intrauterine lesions.
  
  
  CONCLUSIONS
  3D SHG can be used in the initial evaluation of the uterine cavity in women of reproductive age, with accuracy comparable to that of hysteroscopy.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Cairo University, Cairo, Egypt. Electronic address: wssherbiny@kasralainy.edu.eg.
authors.forename: Walid
authors.initials: W
authors.lastname: El-Sherbiny
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Cairo University, Cairo, Egypt.
authors.forename: Akmal
authors.initials: A
authors.lastname: El-Mazny
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Cairo University, Cairo, Egypt.
authors.forename: Nermeen
authors.initials: N
authors.lastname: Abou-Salem
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Cairo University, Cairo, Egypt.
authors.forename: Wael Sayed
authors.initials: WS
authors.lastname: Mostafa
mesh_terms: D000026:Abortion, Habitual / Q000209:etiology; D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D021621:Imaging, Three-Dimensional; D007247:Infertility, Female / Q000209:etiology; D008796:Metrorrhagia / Q000209:etiology; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D012965:Sodium Chloride; D014463:Ultrasonography; D014591:Uterine Diseases / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging*; D014599:Uterus / Q000000981:diagnostic imaging*
chemical_list: D012965:Sodium Chloride
keywords: 2D ultrasound; 3D ultrasound; Intrauterine lesions; Outpatient hysteroscopy; Sonohysterography