title: Novel anti-melanoma treatment: focus on immunotherapy.
abstract: Melanoma is an intractable cancer that is aggressive, lethal, and metastatic. The prognosis of advanced melanoma is very poor because it is insensitive to chemotherapy and radiotherapy. The incidence of melanoma has been ascending stably for years worldwide, accompanied by increasing mortality. New approaches to managing this deadly disease are much anticipated to enhance the cure rate and to extend clinical benefits to patients with metastatic melanoma. Due to its high degree of immunogenicity, melanoma could be a good target for immunotherapy, which has been developed for decades and has achieved certain progress. This article provides an overview of immunotherapy for melanoma.
authors.affiliation: Department of Bone and Soft Tissue Tumor, National Clinical Research Center of Cancer, Tianjin Medical University Cancer Hospital & Institute, Tianjin 30060, P. R. China. yangjilong@tjmuch.com.
authors.forename: Meng-Ze
authors.initials: MZ
authors.lastname: Hao
authors.forename: Wen-Ya
authors.initials: WY
authors.lastname: Zhou
authors.forename: Xiao-Ling
authors.initials: XL
authors.lastname: Du
authors.forename: Ke-Xin
authors.initials: KX
authors.lastname: Chen
authors.forename: Guo-Wen
authors.initials: GW
authors.lastname: Wang
authors.forename: Yun
authors.initials: Y
authors.lastname: Yang
authors.forename: Ji-Long
authors.initials: JL
authors.lastname: Yang
mesh_terms: D006801:Humans; D007167:Immunotherapy; D008545:Melanoma / Q000628:therapy*