title: Infectious crystalline keratopathy predominantly affecting the posterior cornea.
abstract: A case of infectious crystalline keratopathy that affects mainly the posterior stroma is presented. Crystalline infiltrates presented after multiple epithelial defects and chronic topical steroid use following a penetrating keratoplasty in this patient. His epithelial defects persisted and given the deep location of the crystalline infiltrates, a penetrating keratoplasty was performed again. Slit-lamp photo demonstrates the crystalline plaque. Confocal microscopy also documents the aggregates of crystal-like structures. Histology slides are also presented that show the disruption of the stromal-Descemet interface and the predominance of pathology confined to the posterior stroma which has been documented in the literature as a rare finding.
authors.affiliation: Department of Ophthalmology, University of Pittsburgh School of Medicine Pittsburgh, PA 15213, USA.
authors.forename: Nisreen K
authors.initials: NK
authors.lastname: Mesiwala
authors.affiliation: Department of Pathology, University of Pittsburgh School of Medicine Pittsburgh, PA 15213, USA.
authors.forename: Charleen T
authors.initials: CT
authors.lastname: Chu
authors.affiliation: Department of Ophthalmology, University of Pittsburgh School of Medicine Pittsburgh, PA 15213, USA.
authors.forename: Leela V
authors.initials: LV
authors.lastname: Raju
mesh_terms: D000368:Aged; D003315:Cornea / Q000382:microbiology / Q000473:pathology*; D006801:Humans; D015948:Keratoplasty, Penetrating / Q000009:adverse effects*; D008297:Male; D018613:Microscopy, Confocal; D013290:Streptococcal Infections / Q000473:pathology*; D013297:Streptococcus pyogenes
keywords: Crystalline; cornea; keratopathy; penetrating keratoplasty; stroma