title: No advantages of laparoscopy for left-sided malignant colonic obstruction compared with open colorectal resection in both short-term and long-term outcomes.
abstract: Left-sided malignant colonic obstruction is one of the most difficult clinical problems; however, no studies compared the two most common used surgical approach laparoscopic and open colorectomy till now. The purpose of this study was to investigate the short- and long-term outcomes of laparoscopy and open colorectomy for left-sided malignant colonic obstruction. A total of 193 colorectal carcinoma patients (55 patients who underwent laparoscopic colorectomy and 138 who underwent open colorectomy) with left-sided colonic obstruction and surgical therapy, between May 2007 and March 2012, are included in the study. The short-term and long-term outcomes including curative resection rate, hospital stay time, complications, 1-, 3- and 5-year survival rates and recurrence rate, as well as recurrence-free survival rate were analyzed retrospectively. No significant difference was found between the laparoscopic and open groups about the short-term outcomes, such as the curative resection rate (81.82 vs. 78.99%, P=0.658), hospital stay time (24.22±17.09 vs. 24.19±14.76 day, P=0.990), the overall and respective complications (32.73 vs. 39.63%, P=0.674). Long-term outcomes, including 1-, 3- and 5-year survival rates (P=0.518), recurrence rates (P=0.320), and recurrence-free survival rates (P=0.988), were also indicated no significant differences between the two patient groups. Laparoscopy might not have advantages on left-sided malignant colonic obstruction compared with open colorectal resection in both short-term and long-term outcomes.
authors.affiliation: Gastrointestinal Institute of Sun Yat-Sen University, Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-Sen University (Guangdong Gastrointestinal Hospital), 26 Yuancun Erheng Road, Guangzhou, Guangdong, 510655, People's Republic of China.
authors.forename: Zhihua
authors.initials: Z
authors.lastname: Liu
authors.forename: Liang
authors.initials: L
authors.lastname: Kang
authors.forename: Meijin
authors.initials: M
authors.lastname: Huang
authors.forename: Chao
authors.initials: C
authors.lastname: Li
authors.forename: Chao
authors.initials: C
authors.lastname: Tong
authors.forename: Xingwei
authors.initials: X
authors.lastname: Zhang
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
authors.forename: Jianping
authors.initials: J
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D003082:Colectomy; D003110:Colonic Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D007415:Intestinal Obstruction / Q000473:pathology / Q000601:surgery*; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D015996:Survival Rate; D016896:Treatment Outcome