title: Detection of multiple mutations in a single codon of genomic DNA.
abstract: The controller DNA technology allows the detection of multiple mutations in a single codon of genomic DNA. In this technology, the controller DNA is used to control the hybridization of target DNAs with the immobilized DNAs. The controller DNA technology is rapid, specific, and cost-effective for the following reasons, (i) final results in 40 min after PCR, (ii) detection and discrimination of the six mutations in a single codon, and (iii) high sensitivity.
authors.affiliation: Institute for Applied Chemistry and Department of Chemistry, Hallym University, Chuncheon, 200-702, Korea. tskim@hallym.ac.kr.
authors.forename: Danishmalik Rafiq
authors.initials: DR
authors.lastname: Sayyed
authors.forename: Satish Balasaheb
authors.initials: SB
authors.lastname: Nimse
authors.forename: Keum-Soo
authors.initials: KS
authors.lastname: Song
authors.forename: Taisun
authors.initials: T
authors.lastname: Kim
mesh_terms: D003062:Codon / Q000235:genetics*; D004269:DNA, Bacterial / Q000235:genetics*; D009154:Mutation; D009169:Mycobacterium tuberculosis / Q000235:genetics; D016133:Polymerase Chain Reaction; D020641:Polymorphism, Single Nucleotide
chemical_list: D003062:Codon; D004269:DNA, Bacterial