title: Transition into adulthood: tuberous sclerosis complex, Sturge-Weber syndrome, and Rasmussen encephalitis.
abstract: Children with tuberous sclerosis complex, Sturge-Weber syndrome, and Rasmussen encephalitis all have complex but differing needs in the process of transition/transfer to adult care. All three may be associated with long-term normal intelligence or a varying degree of intellectual disability. In tuberous sclerosis complex, the emphasis of care in adulthood shifts from seizure control and developmental issues to renal and psychiatric disease and other issues. In Sturge-Weber syndrome, the emphasis shifts from seizure control and rehabilitation to management of disability and migraine. In Rasmussen encephalitis, transition may be particularly complex for those with adolescent onset. Those successfully operated on for childhood onset have a static problem and the potential to do well in life.
authors.affiliation: Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, U.S.A.
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Thiele
authors.forename: Tiziana
authors.initials: T
authors.lastname: Granata
authors.forename: Sara
authors.initials: S
authors.lastname: Matricardi
authors.forename: Harry T
authors.initials: HT
authors.lastname: Chugani
mesh_terms: D000328:Adult; D004660:Encephalitis / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D008607:Intellectual Disability / Q000150:complications / Q000503:physiopathology*; D012640:Seizures / Q000209:etiology*; D013341:Sturge-Weber Syndrome / Q000150:complications* / Q000503:physiopathology; D060305:Transition to Adult Care; D014402:Tuberous Sclerosis / Q000150:complications* / Q000503:physiopathology
keywords: Rasmussen's encephalitis; Sturge Weber; Tuberous sclerosis