title: Immediate versus delayed primary nerve repair in the rabbit sciatic nerve.
abstract: It is well known that peripheral nerve injury should be treated immediately in the clinic, but in some instances, repair can be delayed. This study investigated the effects of immediate versus delayed (3 days after injury) neurorrhaphy on repair of transected sciatic nerve in New Zealand rabbits using stereological, histomorphological and biomechanical methods. At 8 weeks after immediate and delayed neurorrhaphy, axon number and area in the sciatic nerve, myelin sheath and epineurium thickness, Schwann cell morphology, and the mechanical property of nerve fibers did not differ obviously. These results indicate that delayed neurorrhaphy do not produce any deleterious effect on sciatic nerve repair.
authors.affiliation: Department of Orthopedics and Traumatology, School of Medicine, Ondokuz Mayıs University, Samsun, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Piskin
authors.affiliation: Department of Histology and Embryology, School of Medicine, Ondokuz Mayıs University, Samsun, Turkey.
authors.forename: Berrin Zühal
authors.initials: BZ
authors.lastname: Altunkaynak
authors.affiliation: Department of Orthopedics and Traumatology, School of Medicine, Giresun University, Giresun, Turkey.
authors.forename: Atilla
authors.initials: A
authors.lastname: Çitlak
authors.affiliation: Department of Orthopedics and Traumatology, School of Medicine, Ondokuz Mayıs University, Samsun, Turkey.
authors.forename: Hicabi
authors.initials: H
authors.lastname: Sezgin
authors.affiliation: Department of Orthopedics and Traumatology, School of Medicine, Ondokuz Mayıs University, Samsun, Turkey.
authors.forename: Ozgür
authors.initials: O
authors.lastname: Yazιcι
authors.affiliation: Department of Histology and Embryology, School of Medicine, Ondokuz Mayıs University, Samsun, Turkey.
authors.forename: Süleyman
authors.initials: S
authors.lastname: Kaplan
keywords: biomechanics; delayed peripheral nerve repair; microscopy; neural regeneration; neuroregeneration; peripheral nerve injury; sciatic nerve; stereology