title: Quality control: H2A.X links to better iPSCs.
abstract: Incorporating induced pluripotent stem cell (iPSC) technology in regenerative medicine requires better methods for defining and obtaining high-quality lines. Two papers in this issue of Cell Stem Cell (Buganim et al., 2014; Wu et al., 2014) now show that H2A.X deposition can serve as a functional epigenetic marker for distinguishing the quality of iPSCs, thus providing insights for better reprogramming methods.
authors.affiliation: School of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
authors.forename: Yawei
authors.initials: Y
authors.lastname: Gao
authors.affiliation: School of Life Sciences and Technology, Tongji University, Shanghai 200092, China. Electronic address: gaoshaorong@tongji.edu.cn.
authors.forename: Shaorong
authors.initials: S
authors.lastname: Gao