title: Acoustic monitoring of changes in well-defined hyaluronan layers exposed to chondrocytes.
abstract: The interaction of human-derived chondrocytes and thin hyaluronan layers was studied using the quartz crystal microbalance with dissipation (QCM-D) technique combined with light microscopy. This approach allowed unique real-time monitoring of the interface between the cells and the sensor surface. Our results suggest that the hyaluronan layer is rapidly degraded by chondrocytes.
authors.affiliation: Dept. of Appl. Physics, Chalmers University of Technology, 412 96, Göteborg, Sweden. sofia.svedhem@chalmers.se.
authors.forename: E
authors.initials: E
authors.lastname: Nilebäck
authors.forename: L
authors.initials: L
authors.lastname: Enochson
authors.forename: N
authors.initials: N
authors.lastname: Altgärde
authors.forename: M
authors.initials: M
authors.lastname: Schnabelrauch
authors.forename: A
authors.initials: A
authors.lastname: Lindahl
authors.forename: S
authors.initials: S
authors.lastname: Svedhem
authors.forename: A
authors.initials: A
authors.lastname: Kunze
mesh_terms: D000162:Acoustics; D001672:Biocompatible Materials; D019902:Chondrocytes / Q000166:cytology*; D006820:Hyaluronic Acid / Q000737:chemistry*; D011791:Quartz
chemical_list: D001672:Biocompatible Materials; D011791:Quartz; D006820:Hyaluronic Acid