title: Acute generalized exanthematous pustulosis: atypical presentations and outcomes.
abstract: Acute generalized exanthematous pustulosis (AGEP) is an acute drug eruption characterized by erythematous plaques and papules studded with numerous, pinpoint pustules. Several atypical clinical presentations and triggers of AGEP have been described in the literature. These include systemic presentations similar to toxic epidermal necrolysis (TEN) and drug-induced hypersensitivity syndrome (DIHS) and localized presentations mimicking other medication reactions. We herein aim to review atypical presentations and medication triggers of AGEP to assist clinicians in recognizing this condition and making appropriate therapeutic interventions.
authors.affiliation: Department of Dermatology, Virginia Commonwealth University Medical Center, Richmond, VA, USA.
authors.forename: T C
authors.initials: TC
authors.lastname: Kostopoulos
authors.affiliation: Department of Dermatology, Virginia Commonwealth University Medical Center, Richmond, VA, USA.
authors.forename: S M
authors.initials: SM
authors.lastname: Krishna
authors.affiliation: Department of Dermatology, Virginia Commonwealth University Medical Center, Richmond, VA, USA.
authors.forename: N K
authors.initials: NK
authors.lastname: Brinster
authors.affiliation: Department of Dermatology, Virginia Commonwealth University Medical Center, Richmond, VA, USA.
authors.forename: A G
authors.initials: AG
authors.lastname: Ortega-Loayza
mesh_terms: D056150:Acute Generalized Exanthematous Pustulosis / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D003875:Drug Eruptions / Q000150:complications / Q000628:therapy; D064420:Drug-Related Side Effects and Adverse Reactions / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D005076:Exanthema / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D006801:Humans