title: The Olig family affects central nervous system development and disease.
abstract: Neural cell differentiation and maturation is a critical step during central nervous system development. The oligodendrocyte transcription family (Olig family) is known to be an important factor in regulating neural cell differentiation. Because of this, the Olig family also affects acute and chronic central nervous system diseases, including brain injury, multiple sclerosis, and even gliomas. Improved understanding about the functions of the Olig family in central nervous system development and disease will greatly aid novel breakthroughs in central nervous system diseases. This review investigates the role of the Olig family in central nervous system development and related diseases.
authors.affiliation: Department of Rehabilitation Medicine, Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
authors.forename: Botao
authors.initials: B
authors.lastname: Tan
authors.affiliation: Department of Rehabilitation Medicine, Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Yu
authors.affiliation: Department of Rehabilitation Medicine, Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Yin
authors.affiliation: Department of Rehabilitation Medicine, Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
authors.forename: Gongwei
authors.initials: G
authors.lastname: Jia
authors.affiliation: Department of Rehabilitation Medicine, Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Jiang
authors.affiliation: Department of Rehabilitation Medicine, Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
authors.forename: Lehua
authors.initials: L
authors.lastname: Yu
keywords: NSFC grant; Olig family; astrocytes; brain injury; central nervous system disease; demyelination; development; differentiation; nerve regeneration; neural regeneration; oligodendrocytes; review; spinal cord injury