title: Understanding clinical trials: emerging methodological issues.
authors.affiliation: Northern Clinical School Intensive Care Research Unit, University of Sydney, Sydney, Australia, gdoig@med.usyd.edu.au.
authors.forename: Gordon S
authors.initials: GS
authors.lastname: Doig
authors.forename: Fiona
authors.initials: F
authors.lastname: Simpson
mesh_terms: D005188:False Negative Reactions; D005189:False Positive Reactions; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D012107:Research Design