title: Primary extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue type with malakoplakia in the urinary bladder: a case report.
abstract: Primary malignant lymphoma of the urinary bladder is a rare disease constituting less than 1% of neoplasms of the urinary bladder. The most prevalent histological subtype is extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue type (MALT lymphoma). It is frequently associated with chronic cystitis and predominantly occurs in females. On the other hand, malakoplakia is thought to be a reactive granulomatous lesion occurring most prevalently in the genitourinary tracts. It is frequently found in females and often associated with bacterial infection in immunosuppressive status. Here we report a rare case of concurrent primary MALT lymphoma and malakoplakia in the urinary bladder in a 78-year-old Japanese female. Presumably, both lymphoma and malakoplakia are considered to be involved in the antecedent cystitis and might contribute to the development of the urinary bladder tumor of the patient, leading to the occlusion of the right ureter with subsequent hydronephrosis.
authors.affiliation: Department of Surgical Pathology, Hyogo College of Medicine Hyogo, Japan.
authors.forename: Ikuo
authors.initials: I
authors.lastname: Matsuda
authors.affiliation: Seihoukai Ohyama Hospital Hyogo, Japan.
authors.forename: Masataka
authors.initials: M
authors.lastname: Zozumi
authors.affiliation: Department of Surgical Pathology, Hyogo College of Medicine Hyogo, Japan.
authors.forename: Yasu-aki
authors.initials: YA
authors.lastname: Tsuchida
authors.affiliation: Department of Surgical Pathology, Hyogo College of Medicine Hyogo, Japan.
authors.forename: Naomi
authors.initials: N
authors.lastname: Kimura
authors.affiliation: Department of Surgical Pathology, Hyogo College of Medicine Hyogo, Japan.
authors.forename: Ning-Ning
authors.initials: NN
authors.lastname: Liu
authors.affiliation: Department of Transfusion Medicine, Hyogo College of Medicine Hyogo, Japan.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Fujimori
authors.affiliation: Division of Hematology, Department of Internal Medicine, Hyogo College of Medicine Hyogo, Japan.
authors.forename: Masaya
authors.initials: M
authors.lastname: Okada
authors.affiliation: Department of Urology, Hyogo College of Medicine Hyogo, Japan.
authors.forename: Takahiko
authors.initials: T
authors.lastname: Hashimoto
authors.affiliation: Department of Urology, Hyogo College of Medicine Hyogo, Japan.
authors.forename: Shingo
authors.initials: S
authors.lastname: Yamamoto
authors.affiliation: Department of Surgical Pathology, Hyogo College of Medicine Hyogo, Japan.
authors.forename: Seiichi
authors.initials: S
authors.lastname: Hirota
mesh_terms: D000368:Aged; D003556:Cystitis / Q000150:complications; D005260:Female; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications* / Q000473:pathology; D008287:Malacoplakia / Q000150:complications* / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000150:complications* / Q000473:pathology
keywords: MALT lymphoma; cystitis; malakoplakia; urinary bladder