title: Effect of chair stand exercise on activity of daily living: a randomized controlled trial in hemodialysis patients.
abstract: OBJECTIVE
  Muscle atrophy and weakness impair activity of daily living (ADL). We examined whether chair stand exercise can improve ADL of hemodialysis patients.
  
  
  METHODS
  A randomized controlled trial.
  
  
  METHODS
  A single center study.
  
  
  METHODS
  Outpatients on hemodialysis older than 60 years (61-79 years).
  
  
  METHODS
  Twelve weeks of intervention with chair stand exercise, 3 sessions/week versus the control exercise (stretch, 1 session/week).
  
  
  METHODS
  The primary outcome was the change in functional independence measure (FIM) score from baseline. The secondary outcomes were changes in thigh circumference, muscle strength of quadriceps, 6-minute walking distance, maximum duration of chair stand exercise, health-related quality of life, cognitive function serum albumin, and hemoglobin.
  
  
  RESULTS
  Among the 27 patients who were randomized, 17 completed the study. The change in FIM from baseline was greater in the intervention group (1 [1-3] vs. 0 [0-0], median (minimum to maximum), P < .001) due to the significant improvement in the FIM subscales related to mobility (bed/chair/wheel chair) and locomotion (stair). Among the secondary outcomes, significant difference was noticed in the changes in thigh circumference and the physical component summary score of health-related quality of life by Medical Outcome Study 36-Item Short-Form Health Survey (SF-36v2).
  
  
  CONCLUSIONS
  Chair stand exercise improved ADL in the hemodialysis patients aged older than 60 years.
authors.affiliation: Division of Rehabilitation, Inoue Hospital, Suita, Japan.
authors.forename: Shota
authors.initials: S
authors.lastname: Matsufuji
authors.affiliation: Department of Geriatrics and Vascular Medicine, Graduate School of Medicine, Osaka City University, Osaka, Japan. Electronic address: t-shoji@med.osaka-cu.ac.jp.
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Shoji
authors.affiliation: Division of Rehabilitation, Inoue Hospital, Suita, Japan.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Yano
authors.affiliation: Division of Internal Medicine, Inoue Hospital, Suita, Japan.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Tsujimoto
authors.affiliation: Division of Internal Medicine, Inoue Hospital, Suita, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kishimoto
authors.affiliation: Division of Internal Medicine, Inoue Hospital, Suita, Japan.
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Tabata
authors.affiliation: Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
authors.forename: Masanori
authors.initials: M
authors.lastname: Emoto
authors.affiliation: Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Inaba
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D015444:Exercise / Q000502:physiology; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength / Q000502:physiology; D011446:Prospective Studies; D011788:Quality of Life; D006435:Renal Dialysis; D012709:Serum Albumin / Q000378:metabolism; D016896:Treatment Outcome
chemical_list: D006454:Hemoglobins; D012709:Serum Albumin