title: Glycated albumin is not significantly correlated with body mass index in patients with acute-onset type 1 diabetes.
abstract: BACKGROUND
  No previous reports have clarified the relationship between glycated albumin (GA) and BMI in patients with acute-onset type 1 diabetes.
  
  
  METHODS
  We conducted a cross-sectional study evaluating the correlation between GA and BMI in 209 patients with acute-onset type 1 diabetes and in 159 patients with type 2 diabetes who were designated as the control group. The correlation between fasting serum C-peptide immunoreactivity (CPR) and GA or BMI was also evaluated to clarify the impact of insulin secretion capacity on the relationship between GA and BMI.
  
  
  RESULTS
  GA was significantly inversely correlated with BMI in patients with type 2 diabetes (r=-0.317, p<0.001) but not in patients with type 1 diabetes (r=0.031, p=NS). In patients with type 2 diabetes, GA was significantly inversely correlated with fasting CPR, and BMI was significantly correlated with fasting CPR. In patients with type 1 diabetes, GA was significantly inversely correlated with fasting CPR (r=-0.291, p<0.001), but BMI was not correlated with fasting CPR (r=-0.010, p=NS).
  
  
  CONCLUSIONS
  Unlike in patients with type 2 diabetes, GA was not significantly correlated with BMI in patients with acute-onset type 1 diabetes.
authors.affiliation: Foundation for Biomedical Research and Innovation, Kobe, Japan. Electronic address: t-hirata@fbri.org.
authors.forename: Takumi
authors.initials: T
authors.lastname: Hirata
authors.affiliation: Department of Internal Medicine, Kawanishi City Hospital, Hyogo, Japan.
authors.forename: Masafumi
authors.initials: M
authors.lastname: Koga
authors.affiliation: Department of Medicine, Nissay Hospital, Osaka, Japan.
authors.forename: Soji
authors.initials: S
authors.lastname: Kasayama
authors.affiliation: Department of Internal Medicine, Saitama Social Insurance Hospital, Saitama, Japan.
authors.forename: Jiro
authors.initials: J
authors.lastname: Morimoto
authors.affiliation: Department of Internal Medicine, Saitama Social Insurance Hospital, Saitama, Japan.
authors.forename: Taro
authors.initials: T
authors.lastname: Maruyama
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D015992:Body Mass Index; D002097:C-Reactive Protein / Q000378:metabolism; D003430:Cross-Sectional Studies; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000175:diagnosis; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000175:diagnosis; D005215:Fasting; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D017127:Glycation End Products, Advanced; D006801:Humans; D007328:Insulin / Q000097:blood; D008297:Male; D008875:Middle Aged; D012709:Serum Albumin / Q000378:metabolism*; D000093423:Glycated Serum Albumin
chemical_list: D002097:C-Reactive Protein; D006442:Glycated Hemoglobin; D017127:Glycation End Products, Advanced; D007328:Insulin; D012709:Serum Albumin; D000093423:Glycated Serum Albumin; C517652:hemoglobin A1c protein, human
keywords: Body mass index; C-peptide immunoreactivity; Glycated albumin; Glycated hemoglobin; Type 1 diabetes