title: [Biopsy of brain parenchymal lesions: procedure selection and ingenuity of accurate and safety biopsy].
abstract: BACKGROUND
  Biopsy procedures of intra-parenchymal lesions are divided into needle biopsy (stereotactic or frameless) or navigation-guided endoscopic biopsy.
  
  
  METHODS
  We retrospectively reviewed 36 consecutive patients with intra-parenchymal lesions who underwent biopsy at our institution. Fourteen patients underwent navigation-guided endoscopic biopsy (endoscopic group) and 22 patients underwent needle biopsy (needle group). Rates of pathological diagnosis and postoperative hemorrhage were compared between groups and analyzed using Fisher's exact test. Probability values of <0.05 were considered statistically significant.
  
  
  RESULTS
  Pathological diagnostic rates were 100% (14/14) for the endoscopic group and 96% (21/22) for the needle group, showing no significant difference. The postoperative hemorrhage rate was 7.1% (1/14) in the endoscopic group and 27.3% (6/22) in the needle group (p=0.21). Symptomatic postoperative hemorrhage was seen in 0% (0/14) of the endoscopic group and 18.2% (4/22) in the needle group (p=0.14).
  
  
  CONCLUSIONS
  Both needle and endoscopic biopsies are accurate procedures with high rates of pathological diagnosis. Postoperative hemorrhage tended to be less frequent with endoscopic biopsy than with needle biopsy. Here, we described procedure selection and ingenuity of accurate and safe biopsy at our institution.
authors.affiliation: Department of Neurosurgery, Nagoya Central Hospital.
authors.forename: Takafumi
authors.initials: T
authors.lastname: Tanei
authors.forename: Shigenori
authors.initials: S
authors.lastname: Takebayashi
authors.forename: Norimoto
authors.initials: N
authors.lastname: Nakahara
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Nagatani
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Wakabayashi
mesh_terms: D001706:Biopsy / Q000379:methods; D001932:Brain Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018579:Patient Selection