title: Transition issues for children with diffuse cortical malformations, multifocal postnatal lesions, (infectious and traumatic) and Lennox-Gastaut and similar syndromes.
abstract: Patients with epilepsy may have diffuse, serious brain disorders including genetically determined, multilobar malformations, traumatic brain injury, encephalitis and meningitis, and the many causes of Lennox-Gastaut syndrome. Transition to adult care needs to consider concomitant intellectual disability, refractory epilepsy, underlying cause, and other nonneurologic but significant problems, especially for genetic etiologies. Adult epilepsy care coupled with dedicated primary/family care is essential. A multidisciplinary setting may be optimal to address the many issues of clinical care, decision making, custody, and ongoing supervision.
authors.affiliation: Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada; Department of Pediatrics, IWK Health Centre, Halifax, Nova Scotia, Canada.
authors.forename: Peter R
authors.initials: PR
authors.lastname: Camfield
authors.forename: Nadia
authors.initials: N
authors.lastname: Bahi-Buisson
authors.forename: Eugen
authors.initials: E
authors.lastname: Trinka
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D001930:Brain Injuries / Q000503:physiopathology* / Q000523:psychology; D002648:Child; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis / Q000209:etiology* / Q000235:genetics / Q000628:therapy; D006801:Humans; D008607:Intellectual Disability / Q000175:diagnosis / Q000209:etiology* / Q000235:genetics / Q000628:therapy; D065768:Lennox Gastaut Syndrome; D013036:Spasms, Infantile / Q000175:diagnosis / Q000209:etiology* / Q000235:genetics / Q000628:therapy; D016896:Treatment Outcome
keywords: Cortical malformation; Ence-phalitis; Lennox-Gastaut; Meningitis; Transition; Traumatic brain injury