title: Usefulness of11C-methionine positron emission tomography for detecting intracranial ameloblastic carcinoma: A case report.
abstract: Ameloblastic carcinoma, secondary type, is an extremely rare odontogenic malignant tumor. The present study reports the case of a 58-year-old male with ameloblastic carcinoma that extended into the intracranial space close to the internal carotid artery. Surgical excision was performed, as headaches were being caused via compression by the mass. Small remnants of the tumor remained surrounding the internal carotid artery following surgical resection. Although the remnant tissue was not detected on magnetic resonance imaging or 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET), it was clearly visualized on11C-methionine PET in the early post-operative follow-up period. No neurological deficits were exhibited during the follow-up period, and11C-methionine PET was able to detect the remnant lesion distribution in the intracranial space. The current study presents a rare case of ameloblastic carcinoma that extended into the intracranial space. In addition, several diagnostic imaging tools were compared in order to determine the most suitable imaging modality. At present, the patient is continuing a therapeutic course of radiation and evident mass reduction has been observed. However, the therapeutic effects are currently under consideration. To the best of our knowledge, this is the first study on the effectiveness of using11C-methionine PET for detecting ameloblastic carcinoma with intracranial extension.
authors.affiliation: Department of Neurosurgery, Hokuto Hospital, Hokkaido 080-0833, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Tempaku
authors.affiliation: Department of Neurosurgery, Hokuto Hospital, Hokkaido 080-0833, Japan.
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Takahashi
authors.affiliation: Department of Neurosurgery, Hokuto Hospital, Hokkaido 080-0833, Japan.
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Ikeda
authors.affiliation: Department of Neurosurgery, Hokuto Hospital, Hokkaido 080-0833, Japan.
authors.forename: Shigeru
authors.initials: S
authors.lastname: Yamauchi
authors.affiliation: Department of Otolaryngology, Hokuto Hospital, Hokkaido 080-0833, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Gotoh
authors.affiliation: Department of Otolaryngology, Hokuto Hospital, Hokkaido 080-0833, Japan.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Bandoh
authors.affiliation: Department of Oral and Maxillofacial Surgery, Hokuto Hospital, Hokkaido 080-0833, Japan.
authors.forename: Syujirou
authors.initials: S
authors.lastname: Makino
authors.affiliation: Department of Plastic Surgery, Hokuto Hospital, Hokkaido 080-0833, Japan.
authors.forename: Takuji
authors.initials: T
authors.lastname: Shimada
authors.affiliation: Department of Neurosurgery, Hokuto Hospital, Hokkaido 080-0833, Japan.
authors.forename: Hajime
authors.initials: H
authors.lastname: Kamada
keywords: ameloblastic carcinoma; intracranial extension; methionine-labeled positron emission tomography