title: Broad spectrum anthelmintic potential of Cassia plants.
abstract: OBJECTIVE
  To study the in vitro anthelmintic efficacy of Cassia alata (C. alata), Cassia angustifolia (C. angustifolia) and Cassia occidentalis (C. occidentalis).
  
  
  METHODS
  Crude ethanol extract from leaves of the three plants were prepared in rotary evaporator and different concentrations (10, 20 and 40 mg/mL) of leaf extracts were used for treatment on different representatives of helminthes (Heterakis gallinarum, Raillietina tetragona and Catatropis sp.) from domestic fowl (Gallus gallus domesticus). Loss of motility and death were monitored frequently.
  
  
  RESULTS
  C. alata showed early paralysis in all worms treated followed by C. angustifolia. C. occidentalis in combination with C. alata together caused early paralysis in all treated worms than the combination of C. alata with C. angustfolia. While Heterakis gallinarum in control survived for (81.33±2.07) h, treated worms lost their motility at (5.71±0.10) h, (6.60±0.86) h and (13.95±0.43) h with C. angustifolia, C. alata and C. occidentalis respectively at a concentration of 40 mg/mL which showed better efficacy than albendazole. Catatropis sp. survival period was (26.49±1.38) h in control, but with plant treatment, it lost its motility in just (0.57±0.08) h, (1.00±0.12) h and (1.47±0.40) h at 40 mg/mL concentration of C. alata, C. angustifolia and C. occidentalis respectively. Raillietina tetragona on the other hand became paralysed at (1.68±0.27) h, (2.95±0.29) h and (4.13±0.31) h with above concentrations treated with three plants respectively, however in control it survived up to (81.93±4.71) h.
  
  
  CONCLUSIONS
  This present study indicated broad spectrum vermifugal activity of all plants tested.
authors.affiliation: Parasitology Research Laboratory, Department of Zoology, Visva Bharati, Santiniketan-731235, West Bengal, India.
authors.forename: Suman
authors.initials: S
authors.lastname: Kundu
authors.affiliation: Parasitology Research Laboratory, Department of Zoology, Visva Bharati, Santiniketan-731235, West Bengal, India.
authors.forename: Saptarshi
authors.initials: S
authors.lastname: Roy
authors.affiliation: Parasitology Research Laboratory, Department of Zoology, Visva Bharati, Santiniketan-731235, West Bengal, India.
authors.forename: Larisha Mawkhleing
authors.initials: LM
authors.lastname: Lyndem
keywords: Anthelmintic; Cassia; Extracts; Paralysis; Parasites; Vermifugal