title: Polydimethylsiloxane: a general matrix for high-performance chromatographic NMR spectroscopy.
abstract: The detection and structural characterization of the components of a mixture is a challenging task. Therefore, the development of a facile and general method that enables both the separation and the structural characterization of the components is desired. Diffusion-ordered NMR spectroscopy (DOSY) with the aid of a matrix is a promising tool for this purpose. However, because the currently existing matrices only separate limited components, the application of the DOSY technique is restricted. Herein we introduce a new versatile matrix, poly(dimethylsiloxane), which can fully separate many mixtures of different structural types by liquid-state NMR spectroscopy. With poly(dimethylsiloxane), liquid-state chromatographic NMR spectroscopy could become a general approach for the structural elucidation of mixtures of compounds.
authors.affiliation: Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101 (China). huangsh@qibebt.ac.cn.
authors.forename: Shaohua
authors.initials: S
authors.lastname: Huang
authors.forename: Jun
authors.initials: J
authors.lastname: Gao
authors.forename: Rui
authors.initials: R
authors.lastname: Wu
authors.forename: Shengying
authors.initials: S
authors.lastname: Li
authors.forename: Zhengwu
authors.initials: Z
authors.lastname: Bai
mesh_terms: D004129:Dimethylpolysiloxanes / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*
chemical_list: D004129:Dimethylpolysiloxanes; C013830:baysilon
keywords: NMR spectroscopy; analytical methods; matrices; mixture analysis; poly(dimethylsiloxane)