title: [Treatment of localized prostate cancer by vascular-targeted photodynamic therapy with WST11].
abstract: Focal therapies are new options for the treatment of localized prostate cancer. Vascular-targeted photodynamic therapy (VTP) with WST11 is one of these options. The aim of this treatment is to destroy a targeted area of the prostate by the associated action of the WST11 drug, light exposure and oxygen. The procedure is performed under general anesthesia. Fibers are introduced trans-perineally in the prostate by ultrasound guidance. The injection of WST11 is then performed with light illumination of the specific targeted area. Current data report 83% negative biopsies 6 months after treatment with good tolerance of the treatment. However, VTP still needs to be evaluated.
authors.affiliation: Service d'urologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9, France. Electronic address: souhil.lebdai@gmail.com.
authors.forename: S
authors.initials: S
authors.lastname: Lebdai
authors.affiliation: Service d'urologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9, France.
authors.forename: F
authors.initials: F
authors.lastname: Martin
authors.affiliation: Service d'urologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9, France.
authors.forename: P
authors.initials: P
authors.lastname: Bigot
authors.affiliation: Service d'urologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9, France.
authors.forename: A R
authors.initials: AR
authors.lastname: Azzouzi
mesh_terms: D001429:Bacteriochlorophylls / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010778:Photochemotherapy / Q000379:methods; D011471:Prostatic Neoplasms / Q000098:blood supply / Q000188:drug therapy*
chemical_list: D001429:Bacteriochlorophylls; C503696:padeliporfin