title: Lepromatous leprosy and perianal tuberculosis: a case report and literature review.
abstract: Leprosy is a chronic infectious disease caused by Mycobacterium leprae, a microorganism that usually affects skin and nerves. Although it is usually well-controlled by multidrug therapy (MDT), the disease may be aggravated by acute inflammatory reaction episodes that cause permanent tissue damage particularly to peripheral nerves. Tuberculosis is predominantly a disease of the lungs; however, it may spread to other organs and cause an extrapulmonary infection. Both mycobacterial infections are endemic in developing countries including Brazil, and cases of coinfection have been reported in the last decade. Nevertheless, simultaneous occurrence of perianal cutaneous tuberculosis and erythema nodosum leprosum is very rare, even in countries where both mycobacterial infections are endemic.
authors.affiliation: Department of Dermatology, Botucatu Medical School, São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu São Paulo State, Brasil ; Departamento de Dermatologia e Radioterapia, Faculdade de Medicina de Botucatu, UNESP, Distrito de Rubião Junior, Botucatu, SP CEP 18618-970, Brasil.
authors.forename: Maria Rita
authors.initials: MR
authors.lastname: Parise-Fortes
authors.affiliation: Department of Dermatology, Botucatu Medical School, São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu São Paulo State, Brasil.
authors.forename: Joel Carlos
authors.initials: JC
authors.lastname: Lastória
authors.affiliation: Department of Dermatology, Botucatu Medical School, São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu São Paulo State, Brasil.
authors.forename: Silvio Alencar
authors.initials: SA
authors.lastname: Marques
authors.affiliation: Department of Dermatology, Botucatu Medical School, São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu São Paulo State, Brasil.
authors.forename: Maria Stella Ayres
authors.initials: MS
authors.lastname: Putinatti
authors.affiliation: Department of Dermatology, Botucatu Medical School, São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu São Paulo State, Brasil.
authors.forename: Hamilton Ometto
authors.initials: HO
authors.lastname: Stolf
authors.affiliation: Department of Pathology, Botucatu Medical School, São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu, São Paulo State, Brazil.
authors.forename: Mariângela Ester Alencar
authors.initials: ME
authors.lastname: Marques
authors.affiliation: Department of Dermatology, Botucatu Medical School, São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu São Paulo State, Brasil.
authors.forename: Vidal
authors.initials: V
authors.lastname: Haddad
keywords: Erythema nodosum leprosum; Leprosy; Mycobacteria; Tuberculosis