title: MAP-kinase pathway up or down? Just look at the skin of your patients!
authors.affiliation: aDermatology Service, Gustave Roussy bINSERM U981, Paris Sud University, Villejuif, France.
authors.forename: Caroline
authors.initials: C
authors.lastname: Robert
authors.forename: Marina
authors.initials: M
authors.lastname: Thomas
authors.forename: Christina
authors.initials: C
authors.lastname: Mateus
mesh_terms: D017486:Acneiform Eruptions / Q000150:complications*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage*; D007211:Indoles / Q000627:therapeutic use*; D020930:MAP Kinase Kinase Kinases / Q000378:metabolism*; D008545:Melanoma / Q000150:complications* / Q000188:drug therapy*; D010091:Oximes / Q000008:administration & dosage*; D048493:Proto-Oncogene Proteins B-raf / Q000378:metabolism*; D011728:Pyridones / Q000008:administration & dosage*; D011744:Pyrimidinones / Q000008:administration & dosage*; D012878:Skin Neoplasms / Q000150:complications* / Q000188:drug therapy*; D013449:Sulfonamides / Q000627:therapeutic use*; D000077484:Vemurafenib
chemical_list: D007093:Imidazoles; D007211:Indoles; D010091:Oximes; D011728:Pyridones; D011744:Pyrimidinones; D013449:Sulfonamides; D000077484:Vemurafenib; C560077:trametinib; C482119:BRAF protein, human; D048493:Proto-Oncogene Proteins B-raf; D020930:MAP Kinase Kinase Kinases; C561627:dabrafenib