title: Spatially regulated adult neurogenesis.
abstract: Adult neurogenesis has been the center of attention for decades. Neuroscientists hope to understand the mechanism underlying this phenomenon that might provide a unique perception of brain repair in future. Neurogenesis is referred to the process in which neuronal stem cells and progenitors generate new neurons in non-pathologic setting. Although there are some similarities between two neurogenetic regions including hippocampus and olfactory bulb, however there are some important differences. Regardless of the unique functional roles of ongoing neurogenesis in olfactory bulb and hippocampus, the differences are in terms of consequence of neurogenesis, origin of newly born neurons, responding receptors to nicotine exposure, neuronal migration and GABAergic input between two regions. In this paper, we have briefly reviewed the differences of adult neurogenesis between olfactory bulb and hippocampus.
authors.affiliation: Douglas Hospital Research Centre, Montreal, Quebec, CANADA, H4H 1R3 ; Department of Human Genetics, McGill University, Montreal, Quebec, CANADA, H3H 1B1 ; Department of Psychiatry, McGill University, Montreal, Quebec, CANADA, H3A 1A1.
authors.forename: Azadeh A
authors.initials: AA
authors.lastname: Rikani
authors.affiliation: Douglas Hospital Research Centre, Montreal, Quebec, CANADA, H4H 1R3 ; Department of Human Genetics, McGill University, Montreal, Quebec, CANADA, H3H 1B1.
authors.forename: Zia
authors.initials: Z
authors.lastname: Choudhry
authors.affiliation: Centre for Neurosciences, University of Alberta, Edmonton, Alberta, CANADA, T6G 2E1.
authors.forename: Adnan M
authors.initials: AM
authors.lastname: Choudhry
authors.affiliation: Department of Neurosurgery, University of Pittsburgh, Pittsburgh, PA, USA, 15213.
authors.forename: Georgios
authors.initials: G
authors.lastname: Zenonos
authors.affiliation: Department of Health Sciences, Clifton Hospital, Karachi, Sindh, PAKISTAN, 71000.
authors.forename: Sadaf
authors.initials: S
authors.lastname: Tariq
authors.affiliation: Institute of Integrated Cell-Material Science, Kyoto University, Yoshida Ushinomiyacho, Sakyo - ku, JAPAN, 606-8501.
authors.forename: Nusrat J
authors.initials: NJ
authors.lastname: Mobassarah
keywords: Central nervous system; GABAergic signalling; Hippocampus; Neuronal migration; Olfactory bulb