title: Fetal umbilical vein transplantation for the repair of middle cerebral artery injury.
abstract: It is necessary to investigate the longitudinal tensile mechanical characteristics of the middle cerebral artery and the fetal umbilical vein prior to applying fetal umbilical vein transplantation for repair of injured middle cerebral artery. Fifteen fresh fetal umbilical vein specimens and 15 normal human fresh cadaver middle cerebral artery specimens were collected for longitudinal tensile testing at the speed of 0.5 mm/min and at normal human temperature. The results showed that under 16.0 kPa physiological stress, the strain value of fetal umbilical vein specimens was larger, while the maximal stress and elastic modulus values were less than those of middle cerebral artery specimens. Our findings indicate that fetal umbilical vein has good elastic properties and the stress-strain curve of the fetal umbilical vein is similar to that of the middle cerebral artery. Fetal umbilical vein transplantation can, therefore, potentially repair the injured middle cerebral artery.
authors.affiliation: Department of Vascular Surgery, China-Japan Friendship Hospital of Jilin University, Changchun 130031, Jilin Province, China.
authors.forename: Xuhui
authors.initials: X
authors.lastname: Hou
authors.affiliation: Department of Vascular Surgery, China-Japan Friendship Hospital of Jilin University, Changchun 130031, Jilin Province, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Yuan
authors.affiliation: Department of Vascular Surgery, China-Japan Friendship Hospital of Jilin University, Changchun 130031, Jilin Province, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Yin
authors.affiliation: Department of Vascular Surgery, China-Japan Friendship Hospital of Jilin University, Changchun 130031, Jilin Province, China.
authors.forename: Songbai
authors.initials: S
authors.lastname: Yang
authors.affiliation: Department of Vascular Surgery, China-Japan Friendship Hospital of Jilin University, Changchun 130031, Jilin Province, China.
authors.forename: Lili
authors.initials: L
authors.lastname: Xie
authors.affiliation: Department of Critical Care Medicine, First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
authors.forename: Shiji
authors.initials: S
authors.lastname: Wang
keywords: biomechanics; elastic modulus; fetal umbilical vein; middle cerebral artery; neural regeneration; neuroregeneration; strain; stress; tension; transplantation repair