title: Optimizing selection of antithrombotic therapy in patients requiring PCI and long term anticoagulation.
abstract: There remains clinical equipoise in the appropriate selection of antiplatelet therapy for the patient on long-term anticoagulation requiring percutaneous coronary intervention. Since most of these patients represent an increasingly aging population, the significant risk of thromboembolism and stent thrombosis must be weighed against the risk of major bleeding. This article reviews the current state of evidence to provide a framework for the practicing clinician.
authors.affiliation: University of Arkansas for Medical Sciences (UAMS) & Central Arkansas VA Medical Center, Little Rock, AR.
authors.forename: Mohan
authors.initials: M
authors.lastname: Mallikarjuna Rao Edupuganti
authors.affiliation: Citizens Memorial Hospital, Heart and Vascular Institute, Bolivar, MO.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Marmagkiolis
authors.affiliation: Arkansas Heart Hospital, Little Rock, AR.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Cilingiroglu
authors.affiliation: University of Arkansas for Medical Sciences (UAMS) & Central Arkansas VA Medical Center, Little Rock, AR.
authors.forename: Barry F
authors.initials: BF
authors.lastname: Uretsky
authors.affiliation: University of Arkansas for Medical Sciences (UAMS) & Central Arkansas VA Medical Center, Little Rock, AR. Electronic address: ahakeem@gmail.com.
authors.forename: Abdul
authors.initials: A
authors.lastname: Hakeem
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D062645:Percutaneous Coronary Intervention / Q000379:methods; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D013923:Thromboembolism / Q000188:drug therapy*; D013995:Time
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors
keywords: Dual antiplatelet therapy (DAPT); Oral anticoagulants (OAT); Percutaneous coronary intervention (PCI); Triple antithrombotic therapy (TOAT)