title: Is there any effect of lower extremity deep vein thrombosis which proven by Doppler ultrasonography on cancer recurrence in patients with stage III colon cancer? A study of the Turkish Descriptive Oncological Researches Group.
abstract: This study aimed to determine the predictive value of lower extremity deep vein thrombosis (LE-DVT) on first cancer recurrence in patients with stage III colon cancer. A total of 113 eligible patients with stage III colon cancer were divided into two groups according to whether they had LE-DVT. LE-DVT was detected in 29 (26%) patients. Presence of recurrence with distant metastasis had a significant positive correlation with baseline platelet count, baseline mean platelet volume, and the presence of lower extremity deep vein thrombosis. It was concluded that the relation between disease progression and the presence of LE-DVT in stage III colon cancer is independent of other study variables (P=0.031; OR=4.27; 95% CI 1.89-6.71). We hypothesized that the presence of LE-DVT in patients with stage III colon cancer may predict to early cancer recurrence with distant metastasis.
authors.affiliation: Department of Medical Oncology, Faculty of Medicine, Sitki Kocman University, Mugla, 48000, Turkey, mugla.medicaloncology@gmail.com.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Tanriverdi
authors.forename: Birdal
authors.initials: B
authors.lastname: Yildirim
authors.forename: Suha
authors.initials: S
authors.lastname: Gul
authors.forename: Esin
authors.initials: E
authors.lastname: Cevik
authors.forename: Tulay
authors.initials: T
authors.lastname: Akman
authors.forename: Suna
authors.initials: S
authors.lastname: Cokmert
authors.forename: Kezban Nur
authors.initials: KN
authors.lastname: Pilanci
authors.forename: Nilufer
authors.initials: N
authors.lastname: Avci
authors.forename: Cetin
authors.initials: C
authors.lastname: Ordu
authors.forename: Sabri
authors.initials: S
authors.lastname: Barutca
mesh_terms: D000368:Aged; D003110:Colonic Neoplasms / Q000503:physiopathology*; D005260:Female; D006801:Humans; D035002:Lower Extremity / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000503:physiopathology*; D010865:Pilot Projects; D012008:Recurrence; D012189:Retrospective Studies; D018608:Ultrasonography, Doppler; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000503:physiopathology*