title: En-bloc liver-pancreas transplant in Iran.
abstract: Liver transplant can be challenging in cirrhotic patients with diabetes mellitus. In chronic liver disease, the glucose metabolism is altered; uncontrolled diabetes negatively influences the outcome of liver transplantation and poses difficulty in the management of immediate post transplantation period. Simultaneous liver-pancreas transplantation is an option to prevent early complications due to diabetes and also to improve the quality of life after transplantation in patients with Insulin-Dependent Diabetes Mellitus (IDDM) and chronic liver disease. We report the first en-bloc liver-pancreas transplant done in the transplant history of Iran. We describe the technical details of the procedure as well as the short term outcome after transplantation. In this case report, we also discuss in some details, the surgical, medical and immunological advantages of combined liver-pancreas transplantation as opposed to separate implantation of both organs.
authors.affiliation: Shiraz Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. aliakbarianm@mums.ac.ir.
authors.forename: Saman
authors.initials: S
authors.lastname: Nikeghbalian
authors.affiliation: Shiraz Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Seyed Haider
authors.initials: SH
authors.lastname: Mehdi
authors.affiliation: Shiraz Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran, Surgical Oncology Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Mohsen
authors.initials: M
authors.lastname: Aliakbarian
authors.affiliation: Shiraz Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Kourosh
authors.initials: K
authors.lastname: Kazemi
authors.affiliation: Shiraz Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Alireza
authors.initials: A
authors.lastname: Shamsaeefar
authors.affiliation: Shiraz Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Amin
authors.initials: A
authors.lastname: Bahreini
authors.affiliation: Shiraz Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Siavash
authors.initials: S
authors.lastname: Gholami
authors.affiliation: Shiraz Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran, Surgical Oncology Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Seyed Ali
authors.initials: SA
authors.lastname: Malekhosseini
mesh_terms: D000328:Adult; D015209:Cholangitis, Sclerosing / Q000601:surgery; D006801:Humans; D007492:Iran; D016031:Liver Transplantation / Q000379:methods; D008297:Male; D016035:Pancreas Transplantation / Q000379:methods