title: [Relationship between epigenetics of sperm and embryogenesis].
abstract: Epigenetics comprises the modifications made in gene expressions without changing the DNA sequence itself. Significant epigenetic changes take place during spermatogenesis and fertilization and exert direct influences on embryogenesis. This article provides an overview of the latest researches on epigenetics of male germ cells and a brief discussion on the correlation of sperm with embryogenesis in four aspects: DNA methylation, histone modification, regulation of non-coding RNAs, and genomic imprinting.
authors.forename: Yan-Fang
authors.initials: YF
authors.lastname: He
authors.forename: Jie-Hua
authors.initials: JH
authors.lastname: Ma
authors.forename: Lian-Jun
authors.initials: LJ
authors.lastname: Pan
authors.forename: Yu-Feng
authors.initials: YF
authors.lastname: Huang
mesh_terms: D000818:Animals; D019175:DNA Methylation; D047108:Embryonic Development; D044127:Epigenesis, Genetic; D018392:Genomic Imprinting; D006657:Histones / Q000378:metabolism; D006801:Humans; D008297:Male; D013094:Spermatozoa
chemical_list: D006657:Histones