title: Retrospective analysis of incidental non-trauma associated findings in severely injured patients identified by whole-body spiral CT scans.
abstract: BACKGROUND
  Whole-body Computed Tomography (CT) scan today is considered a crucial imaging technique in the diagnostic work-up of polytrauma patients implicating a potential survival benefit. Apart from prompt identification of life threatening injuries this imaging technique provides an additional benefit by diagnosing incidental non-trauma associated medical diseases. These incidental findings might be also life threatening and warrant urgent therapy. The downside of whole-body CT is a relatively high radiation exposure that might result in an increased life time cancer risk. The aim of this study was to investigate the frequency and type of non trauma associated incidental medical findings in relation to patient age and potential clinical relevance.
  
  
  METHODS
  Between January 1(st) 2011 and December 15th 2012, a total of 704 trauma patients were referred to our hospital's emergency room that triggered trauma room alarm according to our trauma mechanism criteria. Of these 534 (75.8%) received a whole-body CT according to our dedicated multiple trauma protocol. Incidental Findings (IF) were assigned in three groups according to their clinical relevance. Category 1: IF with high medical relevance (urgent life threatening conditions, unless treated) needing early investigations and intervention prior to or shortly after hospital discharge. Category 2: IF with intermediate or low medical relevance, warranting further investigations. Category 3: IF without clinical relevance.
  
  
  RESULTS
  Overall 231 IFs (43.3%) were identified, 36 (6.7%) patients had IFs with a high clinical relevance, 48 (9.0%) with a moderate or minor clinical relevance and 147 (27.5%) with no clinical relevance. The distribution of incidental findings with high or moderate relevance according to age showed an incidence of 2.6%, 6.6% and 8.8% for patients younger than 40 years, 40 to 60 years and older than 60 years, respectively.
  
  
  CONCLUSIONS
  Whole-body CT scans of trauma patients demonstrate a high rate of incidental findings. Potentially life-threatening, medical findings were found in approximately every 15th patient, predominantly aged over 40 years and presenting with minor to moderate injuries and an Injury Severity Score (ISS) of 10 or less.
authors.affiliation: Department of Orthopaedic and Orthopaedic Trauma Surgery, Reconstructive Surgery, University Hospital of Leipzig AöR, Liebigstr. 20, Leipzig 04105, Germany.
authors.forename: Johannes Km
authors.initials: JK
authors.lastname: Fakler
authors.affiliation: Department of Orthopaedic and Orthopaedic Trauma Surgery, Reconstructive Surgery, University Hospital of Leipzig AöR, Liebigstr. 20, Leipzig 04105, Germany.
authors.forename: Orkun
authors.initials: O
authors.lastname: Ozkurtul
authors.affiliation: Department of Orthopaedic and Orthopaedic Trauma Surgery, Reconstructive Surgery, University Hospital of Leipzig AöR, Liebigstr. 20, Leipzig 04105, Germany.
authors.forename: Christoph
authors.initials: C
authors.lastname: Josten
keywords: Incidental findings; Multiple injured; Polytrauma; Whole-body CT