title: Nicotine usage is associated with elevated processing speed, spatial working memory, and visual learning performance in youth at ultrahigh-risk for psychosis.
abstract: Research has stressed a link between nicotine and cognition in schizophrenia but this has not been examined in youth at ultrahigh-risk (UHR) for psychosis. A total of 35 UHR and 32 control participants were assessed for naturalistic nicotine-use and administered a cognitive battery. Smoking was reported more frequently in the UHR group (46%) than controls (22%). Frequent smoking was associated with elevated cognitive performance in the UHR group, highlighting a need for experimental investigations.
authors.affiliation: Department of Psychology and Neuroscience, University of Colorado Boulder, 1905 Colorado Avenue, CB 345 UCB, Boulder, CO 80309-0345, United States. Electronic address: tina.gupta@colorado.edu.
authors.forename: Tina
authors.initials: T
authors.lastname: Gupta
authors.affiliation: Department of Psychology and Neuroscience, University of Colorado Boulder, 1905 Colorado Avenue, CB 345 UCB, Boulder, CO 80309-0345, United States; Center for Neuroscience, University of Colorado Boulder, 1905 Colorado Avenue, Boulder, CO 80309-0345, United States.
authors.forename: Vijay A
authors.initials: VA
authors.lastname: Mittal
mesh_terms: D000293:Adolescent; D003071:Cognition / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D008570:Memory, Short-Term / Q000187:drug effects*; D009483:Neuropsychological Tests; D009538:Nicotine / Q000008:administration & dosage*; D011618:Psychotic Disorders / Q000453:epidemiology*; D012306:Risk; D012559:Schizophrenia / Q000453:epidemiology*; D012907:Smoking / Q000453:epidemiology*; D065853:Spatial Learning / Q000187:drug effects; D065852:Spatial Memory / Q000187:drug effects*; D055815:Young Adult
chemical_list: D009538:Nicotine
keywords: Cognition; Nicotine; Prodrome