title: Monitoring of hematological and hemostatic parameters in neurocritical care patients.
abstract: Anemia and bleeding are paramount concerns in neurocritical care and often relate to the severity of intracranial hemorrhage. Anemia is generally associated with worse outcomes, and efforts to minimize anemia through reduced volume of blood sampled are encouraged. Point-of-care-testing reliably detects the use of non-steroidal anti-inflammatory drugs that may worsen bleeding and reduce platelet activity, particularly in patients with intracerebral hemorrhage. How best to monitor the effect of platelet transfusion or platelet-activating therapy is not well studied. For patients known to take novel oral anticoagulants, drug-specific coagulation tests before neurosurgical intervention are prudent.
authors.affiliation: Departments of Neurology, Neurosurgery, Northwestern University, Chicago, IL, USA, a-naidech@northwestern.edu.
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Naidech
authors.forename: Monisha A
authors.initials: MA
authors.lastname: Kumar
mesh_terms: D000740:Anemia / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D001780:Blood Coagulation Tests; D001930:Brain Injuries / Q000097:blood* / Q000175:diagnosis* / Q000628:therapy; D003422:Critical Care; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D020300:Intracranial Hemorrhages / Q000097:blood* / Q000175:diagnosis* / Q000628:therapy; D018579:Patient Selection; D019990:Perioperative Care; D019095:Point-of-Care Systems
chemical_list: D006454:Hemoglobins