title: Clinical importance of the nonalcoholic fatty liver disease: a review.
abstract: Literature data analysis summarizing features and peculiarities of clinical presentation, pathways and complications of the nonalcoholic fatty liver disease is presented. The key role of insulin resistance, lipid and carbohydrate metabolic disorders, lipid peroxidation and abnormal antioxidant defense system is described. Clinical importance of non-alcoholic fatty liver disease is essential because of a widespread comorbidity and imbalance in the key regulatory body systems.
authors.forename: A A
authors.initials: AA
authors.lastname: Chumak
authors.forename: L M
authors.initials: LM
authors.lastname: Ovsyannikova
authors.forename: E A
authors.initials: EA
authors.lastname: Sarkisova
authors.forename: E V
authors.initials: EV
authors.lastname: Gasanova
mesh_terms: D000975:Antioxidants / Q000378:metabolism*; D050260:Carbohydrate Metabolism; D003937:Diagnosis, Differential; D006801:Humans; D007333:Insulin Resistance; D050356:Lipid Metabolism; D008111:Liver Function Tests; D065626:Non-alcoholic Fatty Liver Disease / Q000175:diagnosis / Q000209:etiology* / Q000378:metabolism
chemical_list: D000975:Antioxidants
keywords: clinical importance; metabolic syndrome; nonalcoholic fatty liver disease