title: Controlling aqueous self-assembly mechanisms by hydrophobic interactions.
abstract: We report an innovative template-assisted synthetic protocol for the selective functionalization of terminal triple bonds in oligophenyleneethynylenes (OPE) by pre-organization in aqueous solution. By this approach, three new OPE-based bolaamphiphiles substituted with hydrophilic poly(2-ethyl-2-oxazoline) (PEtOx) chains of different length have been synthesized. The chain length was observed to strongly influence the aqueous supramolecular polymerization: bolaamphiphiles with longer hydrophilic chains aggregate into spherical nanoparticles in a stepwise fashion, whereas 2D anisotropic platelets are formed cooperatively if shorter PEtOx chains are used. Our results demonstrate that hydrophobic interactions can be strong enough to trigger cooperative effects in aqueous self-assembly processes.
authors.affiliation: Laboratory of Organic and Macromolecular Chemistry, Friedrich Schiller University Jena, Humboldtstr. 10, 07743 Jena (Germany) and Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena (Germany).
authors.forename: Tobias
authors.initials: T
authors.lastname: Rudolph
authors.forename: Naveen
authors.initials: N
authors.lastname: Kumar Allampally
authors.forename: Gustavo
authors.initials: G
authors.lastname: Fernández
authors.forename: Felix H
authors.initials: FH
authors.lastname: Schacher
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D004987:Ethers / Q000737:chemistry*; D006860:Hydrogen Bonding; D057927:Hydrophobic and Hydrophilic Interactions; D011073:Polyamines / Q000737:chemistry*; D058105:Polymerization; D014867:Water / Q000737:chemistry*
chemical_list: D000480:Alkynes; D004987:Ethers; D011073:Polyamines; C436384:phenyleneethynylene; C511916:poly(2-ethyl-2-oxazoline); D014867:Water
keywords: amphiphilic systems; cooperativity; polymers; self-assembly; π-conjugated systems