title: Exuberant clinical picture of Buschke-Fischer-Brauer palmoplantar keratoderma in bedridden patient.
abstract: Buschke-Fisher-Brauer keratoderma is a rare hereditary autosomal dominant disease of incomplete penetrance. Important differential diagnoses include other palmoplantar keratinization disorders, acquired or hereditary, which is done based on the histopathological findings. This diagnosis alerts especially about the possibility of associated neoplasms. Treatment involves topical keratolytic agents, usually with little efficacy, or with long-term systemic retinoids with follow-up of exuberant collateral effects.
authors.affiliation: Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.
authors.forename: João Roberto
authors.initials: JR
authors.lastname: Antonio
authors.affiliation: Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.
authors.forename: Guilherme Bueno de
authors.initials: GB
authors.lastname: Oliveira
authors.affiliation: Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.
authors.forename: Natalia Cristina Pires
authors.initials: NC
authors.lastname: Rossi
authors.affiliation: Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.
authors.forename: Laiza Gabriela Garcia
authors.initials: LG
authors.lastname: Pires
mesh_terms: D000368:Aged; D004817:Epidermis / Q000473:pathology; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000473:pathology*; D007642:Keratosis / Q000473:pathology; D008297:Male