title: Comparative effectiveness trials: generic misassumptions underlying the SUPPORT controversy.
authors.affiliation: University of Texas Health Science Center at Houston, Houston, Texas; jon.e.tyson@uth.tmc.edu.
authors.forename: Jon E
authors.initials: JE
authors.lastname: Tyson
authors.affiliation: Case Western Reserve University, Cleveland, Ohio; and.
authors.forename: Michele
authors.initials: M
authors.lastname: Walsh
authors.affiliation: University of Rochester Medical Center, Rochester, New York.
authors.forename: Carl T
authors.initials: CT
authors.lastname: D'Angio
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000502:physiology; D007258:Informed Consent / Q000592:standards*; D010101:Oxygen Consumption / Q000187:drug effects / Q000502:physiology; D011175:Positive-Pressure Respiration / Q000379:methods / Q000592:standards*; D011663:Pulmonary Surfactants / Q000008:administration & dosage; D016032:Randomized Controlled Trials as Topic / Q000379:methods / Q000592:standards*; D013810:Therapeutic Equivalency; D016896:Treatment Outcome
chemical_list: D011663:Pulmonary Surfactants
keywords: bioethics; clinical trial; comparative effectiveness research; informed consent