title: Anesthetic management of a newborn with trisomy 18 undergoing closure of patent ductus arteriosus and pulmonary artery banding.
abstract: BACKGROUND
  Peri-operative management of infants with trisomy 18 syndrome is challenging due to various congenital cardiac and facial anomalies.
  
  
  METHODS
  We report the anaesthetic management of a 13-day-old neonate with 1 540 g body weight, undergoing closure of patent ductus arteriosus and pulmonary artery banding. Anaesthesia was induced with sevoflurane, fentanyl and rocuronium. Despite dysmorphic facial features, ventilation and endotracheal intubation were achieved uneventfully. Anaesthesia was maintained with sevoflurane and fentanyl and was uneventful. The patient was transferred to the neonatal ICU intubated and with ventilatory support. The baby was extubated on the second day postoperatively.
  
  
  CONCLUSIONS
  Our knowledge of the proper anaesthetic technique for children undergoing palliative or corrective surgery is limited. Further case reports will increase our experience in peri-operative management of children with trisomy 18.
authors.affiliation: Department of Anesthesiology and Reanimation, Faculty of Medicine, Selcuk University, Konya, Turkey. oguzarun@selcuk.edu.tr.
authors.forename: Oguzha
authors.initials: O
authors.lastname: Arun
authors.affiliation: Department of Anesthesiology and Reanimation, Faculty of Medicine, Selcuk University, Konya, Turkey.
authors.forename: Bahar
authors.initials: B
authors.lastname: Oc
authors.affiliation: Department of Cardiovascular Surgery, Faculty of Medicine, Selcuk University, Konya, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Oc
authors.affiliation: Department of Anesthesiology and Reanimation, Faculty of Medicine, Selcuk University, Konya, Turkey.
authors.forename: Ates
authors.initials: A
authors.lastname: Duman
mesh_terms: D000768:Anesthesia, General / Q000379:methods*; D000777:Anesthetics / Q000008:administration & dosage*; D006328:Cardiac Catheterization; D006348:Cardiac Surgical Procedures / Q000379:methods*; D002887:Chromosomes, Human, Pair 18 / Q000235:genetics; D004374:Ductus Arteriosus, Patent / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011651:Pulmonary Artery / Q000601:surgery*; D014314:Trisomy / Q000235:genetics*; D000073842:Trisomy 18 Syndrome; D014656:Vascular Surgical Procedures / Q000379:methods*
chemical_list: D000777:Anesthetics