title: Group-mediated physical activity promotion and mobility in sedentary patients with knee osteoarthritis: results from the IMPACT-pilot trial.
abstract: OBJECTIVE
  To compare the effects of a group-mediated cognitive behavioral exercise intervention (GMCB) with traditional center-based exercise therapy (TRAD) on objectively assessed levels of physical activity (PA) and mobility in sedentary patients with knee osteoarthritis (OA).
  
  
  METHODS
  The Improving Maintenance of Physical Activity in Knee Osteoarthritis Trial-Pilot (IMPACT-P) was a 12-month, 2-arm, single-blind, randomized controlled pilot study designed to compare the effects of GMCB and TRAD on 80 sedentary patients with knee OA with self-reported difficulty in daily activities [mean age 63.5 yrs, 84% women, mean body mass index (BMI) 32.7 kg/m(2)]. Objective assessments of PA (LIFECORDER Plus Accelerometer) and mobility (400-m walk) were obtained at baseline, 3 months, and 12 months by study personnel blinded to participants' treatment assignment.
  
  
  RESULTS
  Intent to treat 2 (treatment: GMCB and TRAD) × 2 (time: 3 mos and 12 mos) analyses of covariance of controlling for baseline, age, sex, and BMI-adjusted change in the outcomes demonstrated that the GMCB intervention yielded significantly greater increases in PA (p < 0.01) and a nonsignificant yet more favorable improvement in mobility (p = 0.09) relative to TRAD. Partial correlation analyses also revealed that change in PA was significantly correlated with the 400-m walk performance at 3-month (r = -0.51, p < 0.01) and 12-month (r = -0.40, p < 0.01) followup assessments.
  
  
  CONCLUSIONS
  Findings from the IMPACT-P trial suggest that the GMCB treatment resulted in significantly greater improvement in PA and nonsignificant yet more favorable change in mobility relative to TRAD.
authors.affiliation: The Ohio State University, Columbus; Capital University, Columbus, Ohio; Abilene Christian University, Abilene, Texas; Wake Forest University, Winston-Salem, North Carolina, United States.B.C. Focht, PhD, FACSM, CSCS; S.T. Devor, PhD; A.R. Lucas, MS, Kinesiology, Department of Human Sciences; C.F. Emery, PhD, Psychology; K.V. Hackshaw, MD, Internal Medicine, The Ohio State University; M.J. Garver, PhD, Kinesiology, Nutrition, Abilene Christian University; J. Dials, PhD, Exercise Science, Capital University; W.J. Rejeski, PhD, Health and Exercise Science, Wake Forest University. focht.10@osu.edu.
authors.forename: Brian C
authors.initials: BC
authors.lastname: Focht
authors.affiliation: The Ohio State University, Columbus; Capital University, Columbus, Ohio; Abilene Christian University, Abilene, Texas; Wake Forest University, Winston-Salem, North Carolina, United States.B.C. Focht, PhD, FACSM, CSCS; S.T. Devor, PhD; A.R. Lucas, MS, Kinesiology, Department of Human Sciences; C.F. Emery, PhD, Psychology; K.V. Hackshaw, MD, Internal Medicine, The Ohio State University; M.J. Garver, PhD, Kinesiology, Nutrition, Abilene Christian University; J. Dials, PhD, Exercise Science, Capital University; W.J. Rejeski, PhD, Health and Exercise Science, Wake Forest University.
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Garver
authors.affiliation: The Ohio State University, Columbus; Capital University, Columbus, Ohio; Abilene Christian University, Abilene, Texas; Wake Forest University, Winston-Salem, North Carolina, United States.B.C. Focht, PhD, FACSM, CSCS; S.T. Devor, PhD; A.R. Lucas, MS, Kinesiology, Department of Human Sciences; C.F. Emery, PhD, Psychology; K.V. Hackshaw, MD, Internal Medicine, The Ohio State University; M.J. Garver, PhD, Kinesiology, Nutrition, Abilene Christian University; J. Dials, PhD, Exercise Science, Capital University; W.J. Rejeski, PhD, Health and Exercise Science, Wake Forest University.
authors.forename: Steven T
authors.initials: ST
authors.lastname: Devor
authors.affiliation: The Ohio State University, Columbus; Capital University, Columbus, Ohio; Abilene Christian University, Abilene, Texas; Wake Forest University, Winston-Salem, North Carolina, United States.B.C. Focht, PhD, FACSM, CSCS; S.T. Devor, PhD; A.R. Lucas, MS, Kinesiology, Department of Human Sciences; C.F. Emery, PhD, Psychology; K.V. Hackshaw, MD, Internal Medicine, The Ohio State University; M.J. Garver, PhD, Kinesiology, Nutrition, Abilene Christian University; J. Dials, PhD, Exercise Science, Capital University; W.J. Rejeski, PhD, Health and Exercise Science, Wake Forest University.
authors.forename: Justin
authors.initials: J
authors.lastname: Dials
authors.affiliation: The Ohio State University, Columbus; Capital University, Columbus, Ohio; Abilene Christian University, Abilene, Texas; Wake Forest University, Winston-Salem, North Carolina, United States.B.C. Focht, PhD, FACSM, CSCS; S.T. Devor, PhD; A.R. Lucas, MS, Kinesiology, Department of Human Sciences; C.F. Emery, PhD, Psychology; K.V. Hackshaw, MD, Internal Medicine, The Ohio State University; M.J. Garver, PhD, Kinesiology, Nutrition, Abilene Christian University; J. Dials, PhD, Exercise Science, Capital University; W.J. Rejeski, PhD, Health and Exercise Science, Wake Forest University.
authors.forename: Alexander R
authors.initials: AR
authors.lastname: Lucas
authors.affiliation: The Ohio State University, Columbus; Capital University, Columbus, Ohio; Abilene Christian University, Abilene, Texas; Wake Forest University, Winston-Salem, North Carolina, United States.B.C. Focht, PhD, FACSM, CSCS; S.T. Devor, PhD; A.R. Lucas, MS, Kinesiology, Department of Human Sciences; C.F. Emery, PhD, Psychology; K.V. Hackshaw, MD, Internal Medicine, The Ohio State University; M.J. Garver, PhD, Kinesiology, Nutrition, Abilene Christian University; J. Dials, PhD, Exercise Science, Capital University; W.J. Rejeski, PhD, Health and Exercise Science, Wake Forest University.
authors.forename: Charles F
authors.initials: CF
authors.lastname: Emery
authors.affiliation: The Ohio State University, Columbus; Capital University, Columbus, Ohio; Abilene Christian University, Abilene, Texas; Wake Forest University, Winston-Salem, North Carolina, United States.B.C. Focht, PhD, FACSM, CSCS; S.T. Devor, PhD; A.R. Lucas, MS, Kinesiology, Department of Human Sciences; C.F. Emery, PhD, Psychology; K.V. Hackshaw, MD, Internal Medicine, The Ohio State University; M.J. Garver, PhD, Kinesiology, Nutrition, Abilene Christian University; J. Dials, PhD, Exercise Science, Capital University; W.J. Rejeski, PhD, Health and Exercise Science, Wake Forest University.
authors.forename: Kevin V
authors.initials: KV
authors.lastname: Hackshaw
authors.affiliation: The Ohio State University, Columbus; Capital University, Columbus, Ohio; Abilene Christian University, Abilene, Texas; Wake Forest University, Winston-Salem, North Carolina, United States.B.C. Focht, PhD, FACSM, CSCS; S.T. Devor, PhD; A.R. Lucas, MS, Kinesiology, Department of Human Sciences; C.F. Emery, PhD, Psychology; K.V. Hackshaw, MD, Internal Medicine, The Ohio State University; M.J. Garver, PhD, Kinesiology, Nutrition, Abilene Christian University; J. Dials, PhD, Exercise Science, Capital University; W.J. Rejeski, PhD, Health and Exercise Science, Wake Forest University.
authors.forename: W Jack
authors.initials: WJ
authors.lastname: Rejeski
mesh_terms: D000368:Aged; D015992:Body Mass Index; D005081:Exercise Therapy; D005260:Female; D006293:Health Promotion; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D020370:Osteoarthritis, Knee / Q000534:rehabilitation*; D010865:Pilot Projects; D016037:Single-Blind Method; D016896:Treatment Outcome; D016138:Walking
keywords: AGING; EXERCISE; MOBILITY; OSTEOARTHRITIS; PHYSICAL ACTIVITY