title: The ultrasounds-ionic liquids synergy on the copper catalyzed azide-alkyne cycloaddition between phenylacetylene and 4-azidoquinoline.
abstract: The effect of ultrasound irradiation on the copper catalyzed azide-alkyne cycloaddition between phenylacetylene and 4-azidoquinoline has been studied in solution of different ionic liquids. In particular, we used ionic liquids featuring both aliphatic and aromatic mono- and dications, as well as anions differing in size, symmetry and coordination ability. We also examined the influence of the ionic liquids structural features on the reaction outcomes, finding that under magnetic stirring reactivity is favorably affected by the solvent structural organization, while under sonochemical conditions an opposite trend was observed. In all cases examined, sonochemical activation leads to significant reduction in energy consumption as compared to the reaction conducted under magnetic stirring.
authors.affiliation: Dipartimento STEBICEF, Sezione di Chimica, Viale delle Scienze-Parco d'Orleans II, 90128 Palermo, Italy. Electronic address: salvatore.marullo@unipa.it.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Marullo
authors.affiliation: Dipartimento STEBICEF, Sezione di Chimica, Viale delle Scienze-Parco d'Orleans II, 90128 Palermo, Italy. Electronic address: francesca.danna@unipa.it.
authors.forename: Francesca
authors.initials: F
authors.lastname: D'Anna
authors.affiliation: Dipartimento STEBICEF, Sezione di Chimica, Viale delle Scienze-Parco d'Orleans II, 90128 Palermo, Italy.
authors.forename: Carla
authors.initials: C
authors.lastname: Rizzo
authors.affiliation: Dipartimento STEBICEF, Sezione di Chimica, Viale delle Scienze-Parco d'Orleans II, 90128 Palermo, Italy.
authors.forename: Renato
authors.initials: R
authors.lastname: Noto
keywords: Azide–alkyne cycloaddition; Ionic liquids; Ultrasound irradiation