title: Facilitating the Cope rearrangement by partial protonation: implications for synthesis and biosynthesis.
abstract: The theoretical investigation of concerted and stepwise Cope rearrangements of natural products led to the prediction that some concerted Cope rearrangements can be promoted by noncovalent association of their transition state structures with ammonium cations.
authors.affiliation: Department of Chemistry, University of California-Davis , 1 Shields Avenue, Davis, California 95616, United States.
authors.forename: Phillip P
authors.initials: PP
authors.lastname: Painter
authors.forename: Bonnie M
authors.initials: BM
authors.lastname: Wong
authors.forename: Dean J
authors.initials: DJ
authors.lastname: Tantillo
mesh_terms: D064751:Ammonium Compounds / Q000737:chemistry; D016227:Benzoquinones / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D031213:Cordia / Q000737:chemistry; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D013729:Terpenes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
chemical_list: D064751:Ammonium Compounds; D016227:Benzoquinones; D001688:Biological Products; D013729:Terpenes; C550791:globiferin