title: Prolonged treatment with large doses of fosfomycin plus vancomycin and amikacin in a case of bacteraemia due to methicillin-resistant Staphylococcus epidermidis and IMP-8 metallo-β-lactamase-producing Klebsiella oxytoca.
authors.affiliation: Internal Medicine Service, Hospital de Valme, Seville, Spain vergara_lopez@yahoo.com.
authors.forename: Salvador
authors.initials: S
authors.lastname: Vergara-López
authors.affiliation: Laboratory of Microbiology, Hospital La Merced, Osuna, Seville, Spain.
authors.forename: M Carmen
authors.initials: MC
authors.lastname: Domínguez
authors.affiliation: Department of Microbiology, University of Seville, Seville, Spain.
authors.forename: M Carmen
authors.initials: MC
authors.lastname: Conejo
authors.affiliation: Department of Microbiology, University of Seville, Seville, Spain Infectious Diseases and Clinical Microbiology Unit, University Hospital Virgen Macarena, Seville, Spain.
authors.forename: Álvaro
authors.initials: Á
authors.lastname: Pascual
authors.affiliation: Infectious Diseases and Clinical Microbiology Unit, University Hospital Virgen Macarena, Seville, Spain Department of Medicine, University of Seville, Seville, Spain.
authors.forename: Jesús
authors.initials: J
authors.lastname: Rodríguez-Baño
mesh_terms: D000368:Aged; D000583:Amikacin / Q000008:administration & dosage*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D016470:Bacteremia / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D060085:Coinfection / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D005578:Fosfomycin / Q000008:administration & dosage*; D006801:Humans; D007710:Klebsiella Infections / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D041121:Klebsiella oxytoca / Q000201:enzymology / Q000302:isolation & purification; D008297:Male; D016106:Methicillin Resistance; D013203:Staphylococcal Infections / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D013212:Staphylococcus epidermidis / Q000187:drug effects / Q000302:isolation & purification; D016896:Treatment Outcome; D014640:Vancomycin / Q000008:administration & dosage*; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D005578:Fosfomycin; D014640:Vancomycin; D000583:Amikacin; C436760:IMP-8 enzyme; D001618:beta-Lactamases
keywords: adverse effects; bacteraemia treatment; carbapenem resistance; carbapenemases; infectious endocarditis