title: The critical role of Th17 cells, Treg cells and co-stimulatory molecules in the development of pre-eclampsia.
abstract: There are suggestions in the literature that pre-eclampsia has an immunological basis, in which there is a failure of the immune system to recognize fetal alloantigens. It seems that abnormal activation of the inflammatory response may play a role in the etiopathogenesis of pre-eclampsia. Many authors have found a number of changes in the immune system which might have contributed to its development. Recent data suggest that pre-eclampsia is a Th17/Treg imbalance with a predominance of Th17 immunity.
authors.affiliation: Department of Obstetrics and Perinatology, Medical University of Lublin, Jaczewskiego 8, 20-950 Lublin, Poland, dorotak@mp.pl.
authors.forename: Dorota
authors.initials: D
authors.lastname: Darmochwał-Kolarz
authors.forename: Jan
authors.initials: J
authors.lastname: Oleszczuk