title: Distribution of Galanin and Galanin Receptor 2 in the Pre-optic Area of the Female Guinea Pig.
abstract: This study describes the distribution of galanin (Gal) and galanin receptor 2 (GalR2) in the pre-optic area (POA) of the female guinea pig. Frozen sections were undergone for a routine immunofluorescence labelling. Gal and GalR2 display immunoreactivity in all parts of the pre-optic area. Gal shows reactivity both in perikarya and fibres, whereas GalR2 was observed only in perikarya. Gal- and GalR2-immunoreactive (-ir) perikarya were the most numerous in the medial pre-optic area (MPA) with the highest reactivity in its dorsal part. In the median pre-optic nucleus (MPN) and periventricular pre-optic nucleus (PPN), only single Gal- and GalR2-ir neurons were observed. The highest density of Gal-ir fibres was revealed in the PPN and the lowest in the lateral pre-optic area (LPA). The results of this study indicate that the distribution pattern of Gal containing neurons overlaps well with the distribution pattern of GalR2-positive neurons, especially in the MPA. This may suggest GalR2-dependent activity in this brain region.
authors.affiliation: Department of Comparative Anatomy, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, pl. Łódzki 3, 10-727, Olsztyn, Poland.
authors.forename: B
authors.initials: B
authors.lastname: Hermanowicz
authors.affiliation: Department of Comparative Anatomy, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, pl. Łódzki 3, 10-727, Olsztyn, Poland.
authors.forename: K
authors.initials: K
authors.lastname: Bogus-Nowakowska
authors.affiliation: Department of Comparative Anatomy, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, pl. Łódzki 3, 10-727, Olsztyn, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Równiak
authors.affiliation: Department of Comparative Anatomy, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, pl. Łódzki 3, 10-727, Olsztyn, Poland.
authors.forename: W
authors.initials: W
authors.lastname: Żakowski
authors.affiliation: Department of Comparative Anatomy, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, pl. Łódzki 3, 10-727, Olsztyn, Poland.
authors.forename: B
authors.initials: B
authors.lastname: Wasilewska
authors.affiliation: Department of Comparative Anatomy, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, pl. Łódzki 3, 10-727, Olsztyn, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Najdzion
authors.affiliation: Department of Comparative Anatomy, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, pl. Łódzki 3, 10-727, Olsztyn, Poland.
authors.forename: A
authors.initials: A
authors.lastname: Robak
mesh_terms: D000818:Animals; D003712:Dendrites / Q000737:chemistry; D005260:Female; D005455:Fluorescent Antibody Technique / Q000662:veterinary; D005629:Frozen Sections / Q000662:veterinary; D019004:Galanin / Q000032:analysis*; D006168:Guinea Pigs / Q000378:metabolism*; D009474:Neurons / Q000737:chemistry; D011301:Preoptic Area / Q000737:chemistry* / Q000378:metabolism; D044092:Receptor, Galanin, Type 2 / Q000032:analysis*
chemical_list: D044092:Receptor, Galanin, Type 2; D019004:Galanin