title: Endoscopic diagnosis of intramural hematoma in the colon sigmoideum in a child with high titer inhibitory hemophilia A.
abstract: Lower gastrointestinal bleeding is a rare condition in childhood pathology. The incidence of this disorder in the general population of Bulgarian children is unknown. We report a case of a 7-year-old child with diagnosed hemophilia A and high titer of factor VIII inhibitor; the patient was admitted into the Department of Pediatrics and Medical Genetics for rectorrhagia after falling onto his buttocks while playing. Colonoscopy showed submucosal hematoma 25 cm from the anocutaneous line occluding the intestinal lumen with a lesion of the overlying mucosa as long as 20 mm. If a patient presents with rectorrhagia, timely and carefully planned colonoscopy could identify the source of bleeding, determine the severity of bleeding and the size of hematoma, and assess the need for surgical intervention. The reported case supports the modern view that patients with inhibitor hemophilia should not be denied interventional procedure or surgical intervention for fear of uncontrolled bleeding.
authors.affiliation: Department of Pediatrics and Medical Genetics
authors.forename: Ivan V
authors.initials: IV
authors.lastname: Yankov
authors.affiliation: Department of Pediatrics and Medical Genetics
authors.forename: Maria I
authors.initials: MI
authors.lastname: Spasova
authors.affiliation: Division of Gastroenterology, Second Department of Internal Medicine
authors.forename: Vladimir N
authors.initials: VN
authors.lastname: Andonov
authors.affiliation: Division of Gastroenterology, Second Department of Internal Medicine
authors.forename: Efimia N
authors.initials: EN
authors.lastname: Cholakova
authors.affiliation: Division of Pediatric Surgery, Department of Basic Sciences of Surgical Diseases, St George University Hospital, Faculty of Medicine, Medical University, Plovdiv, Bulgaria
authors.forename: Alexander S
authors.initials: AS
authors.lastname: Yonkov
mesh_terms: D002648:Child; D003113:Colonoscopy; D003937:Diagnosis, Differential; D006406:Hematoma / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D006467:Hemophilia A / Q000150:complications*; D006801:Humans; D008297:Male; D012810:Sigmoid Diseases / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy