title: [Successful anesthetic management of a patient with giant pheochromocytoma using high-dose landiolol hydrochloride].
abstract: We report successful anesthetic management of a patient with pheochromocytoma using high-dose landiolol hydrochloride. A 55-year-old man was scheduled to undergo resection of giant pheochromocytoma. Epidural anesthesia was not performed due to anticoagulant therapy for lower limb thrombus. Tracheal intubation was performed with the Pentax-AWS Airwayscope. Preoperative screening revealed urine adrenaline 2.567.0 microg x day(-1) urine noradrenaline 1,734.0 microg x day(-1), and a tumor diameter of 96 x 60 mm. Catecholamine surge was controlled with 50 microg x kg(-1) x min(-1) continuous infusion of landiolol hydrochloride and IV bolus phentolamine. On tumor resection, although systemic blood pressure increased to 294 mmHg and was unresponsive to repeated phentolamine administration, the heart rate remained at 70-105 beats x min(-1) and there were no significant ST changes.
authors.forename: Manabu
authors.initials: M
authors.lastname: Kitano
authors.forename: Nobuyasu
authors.initials: N
authors.lastname: Komasawa
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Sawai
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Minami
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000378:metabolism / Q000601:surgery*; D015360:Analgesia, Epidural; D000768:Anesthesia, General; D001145:Arrhythmias, Cardiac / Q000517:prevention & control; D002395:Catecholamines / Q000378:metabolism; D000075202:Contraindications; D006339:Heart Rate; D006801:Humans; D006973:Hypertension / Q000517:prevention & control; D007262:Infusions, Intravenous; D007275:Injections, Intravenous; D007431:Intraoperative Complications / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D009025:Morpholines / Q000008:administration & dosage; D010646:Phentolamine / Q000008:administration & dosage; D010673:Pheochromocytoma / Q000378:metabolism / Q000601:surgery*; D014508:Urea / Q000008:administration & dosage / Q000031:analogs & derivatives*
chemical_list: D002395:Catecholamines; D009025:Morpholines; C077049:landiolol; D014508:Urea; D010646:Phentolamine