title: Spermidinium closo-dodecaborate-encapsulating liposomes as efficient boron delivery vehicles for neutron capture therapy.
abstract: closo-Dodecaborate-encapsulating liposomes were developed as boron delivery vehicles for neutron capture therapy. The use of spermidinium as a counter cation of closo-dodecaborates was essential not only for the preparation of high boron content liposome solutions but also for efficient boron delivery to tumors.
authors.affiliation: Chemical Resources Laboratory, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan. hiro@res.titech.ac.jp.
authors.forename: Shoji
authors.initials: S
authors.lastname: Tachikawa
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Miyoshi
authors.forename: Hayato
authors.initials: H
authors.lastname: Koganei
authors.forename: Mohamed E
authors.initials: ME
authors.lastname: El-Zaria
authors.forename: Clara
authors.initials: C
authors.lastname: Viñas
authors.forename: Minoru
authors.initials: M
authors.lastname: Suzuki
authors.forename: Koji
authors.initials: K
authors.lastname: Ono
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakamura
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000737:chemistry; D001895:Boron / Q000008:administration & dosage; D001896:Boron Compounds / Q000008:administration & dosage* / Q000737:chemistry; D016754:Boron Neutron Capture Therapy; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D005260:Female; D008081:Liposomes; D008807:Mice, Inbred BALB C; D009369:Neoplasms / Q000473:pathology / Q000628:therapy; D047368:Tumor Burden / Q000187:drug effects
chemical_list: D000970:Antineoplastic Agents; D001896:Boron Compounds; D008081:Liposomes; C119788:dodecaborate; D001895:Boron