title: Binocular interaction of visually evoked cortical potentials elicited by dichoptic binocular stimulation.
abstract: To analyze the interaction of cortical potentials elicited by dichoptic stimulation of the dominant and fellow eyes at different frequencies, a pair of programmed power supply units were used to drive a light emitting diode (LED) mounted in the right and left eyes of light-proof goggles to elicit the visually evoked cortical responses (VECPs). The right eye was stimulated at 11.5 Hz and the left eye at 11.0 Hz. Then the stimulation was repeated with the frequency of stimulation switched to the other eyes. The stimulus duration was 5 ms. The sampling rate was 1.0 Hz, and the duration of collection was 200 ms. The VECP of each eye was extracted separately. Individual VECPs could be recorded separately after simultaneous dichoptic stimulation of each eye. The amplitudes of the VECPs were not significantly different after stimulating the dominant eye and the fellow eye separately. The implicit times of negative peak (N-2) and the second positive peak (P-2) were shorter after stimulation of the dominant eye than after stimulation of the fellow eye, but the difference was not significant. However, the implicit time of N-2 elicited by stimulating the dominant eye was significantly shorter when the stimulation rate was 11.5 Hz. The VECPs elicited by stimulating the two eyes can be recorded separately by simultaneous dichoptic stimulation. Dichoptic simultaneous stimulation required a shorter time and may be a more sensitive method of analyzing binocular interactions compared to the classic VECPs using monocular stimulation.
authors.affiliation: Department of Ophthalmology, Teikyo University School of Medicine, Tokyo, Japan Matsumoto Eye Clinic, Tokushima, Japan.
authors.forename: Celso Soiti
authors.initials: CS
authors.lastname: Matsumoto
authors.affiliation: Department of Orthoptics, Faculty of Medical Technology Teikyo University, Tokyo, Japan.
authors.forename: Ryota
authors.initials: R
authors.lastname: Nakagomi
authors.affiliation: Department of Ophthalmology, Teikyo University School of Medicine, Tokyo, Japan Matsumoto Eye Clinic, Tokushima, Japan.
authors.forename: Harue
authors.initials: H
authors.lastname: Matsumoto
authors.affiliation: Department of Ophthalmology, Teikyo University School of Medicine, Tokyo, Japan.
authors.forename: Haruka
authors.initials: H
authors.lastname: Minoda
authors.affiliation: Department of Ophthalmology, Teikyo University School of Medicine, Tokyo, Japan.
authors.forename: Kei
authors.initials: K
authors.lastname: Shinoda
authors.affiliation: National Institute of Sensory Organs, National Tokyo Medical Center, Tokyo, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Iwata
authors.affiliation: Department of Ophthalmology, Teikyo University School of Medicine, Tokyo, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Mizota
mesh_terms: D005074:Evoked Potentials, Visual / Q000502:physiology*; D005260:Female; D006801:Humans; D008027:Light; D008297:Male; D010775:Photic Stimulation / Q000379:methods; D015348:Vision, Binocular / Q000502:physiology*; D014793:Visual Cortex / Q000502:physiology*; D055815:Young Adult
keywords: binocular interaction; dominant eye; hole in card test; visually evoked cortical potential