title: Visual electrochemiluminescence detection of telomerase activity based on multifunctional Au nanoparticles modified with G-quadruplex deoxyribozyme and luminol.
abstract: A novel visual electrochemiluminescence (ECL) analysis strategy for detection of telomerase activity is reported on a microarray chip, with G-quadruplex deoxyribozyme (DNAzyme) and luminol modified Au nanoparticles (NPs) as double-catalytic amplification labels.
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China. xujj@nju.edu.cn.
authors.forename: Huai-Rong
authors.initials: HR
authors.lastname: Zhang
authors.forename: Yin-Zhu
authors.initials: YZ
authors.lastname: Wang
authors.forename: Mei-Sheng
authors.initials: MS
authors.lastname: Wu
authors.forename: Qiu-Mei
authors.initials: QM
authors.lastname: Feng
authors.forename: Hai-Wei
authors.initials: HW
authors.lastname: Shi
authors.forename: Hong-Yuan
authors.initials: HY
authors.lastname: Chen
authors.forename: Jing-Juan
authors.initials: JJ
authors.lastname: Xu
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D045744:Cell Line, Tumor; D021881:DNA, Catalytic / Q000737:chemistry* / Q000378:metabolism; D054856:G-Quadruplexes; D006046:Gold / Q000737:chemistry*; D006801:Humans; D056656:Lab-On-A-Chip Devices; D008163:Luminescent Measurements / Q000379:methods*; D008165:Luminol / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D019098:Telomerase / Q000032:analysis / Q000378:metabolism*
chemical_list: D021881:DNA, Catalytic; D008165:Luminol; D006046:Gold; D019098:Telomerase