title: Treatment of congenital pulmonary lymphangiectasia using ethiodized oil lymphangiography.
abstract: Historically, congenital pulmonary lymphangiectasia (CPL) has had poor treatment outcomes despite aggressive therapy. There are recent reports of ethiodized oil (Lipiodol) lymphangiography successfully treating lymphatic leakage in adults. In this report, we describe two infants with CPL complicated by chylothoraces successfully treated by instillation of ethiodized oil into the lymphatic system. Congenital atresia of the thoracic duct was demonstrated on the lymphangiogram in both patients before treatment. Both patients have shown good short-term outcomes without supplemental oxygen or fat restricted diets at 9 months of age. Ethiodized oil lymphangiography represents a new treatment modality for some patients with CPL.
authors.affiliation: Division of Neonatology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
authors.forename: M
authors.initials: M
authors.lastname: Gray
authors.affiliation: Division of Neonatology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
authors.forename: K Z
authors.initials: KZ
authors.lastname: Kovatis
authors.affiliation: Division of Neonatology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
authors.forename: T
authors.initials: T
authors.lastname: Stuart
authors.affiliation: Division of Neonatology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
authors.forename: E
authors.initials: E
authors.lastname: Enlow
authors.affiliation: Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: M
authors.initials: M
authors.lastname: Itkin
authors.affiliation: Division of Interventional Radiology, Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: M S
authors.initials: MS
authors.lastname: Keller
authors.affiliation: Division of Neonatology, Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: H M
authors.initials: HM
authors.lastname: French
mesh_terms: D003287:Contrast Media / Q000627:therapeutic use*; D004621:Embolization, Therapeutic; D004998:Ethiodized Oil / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007223:Infant; D008171:Lung Diseases / Q000151:congenital* / Q000000981:diagnostic imaging / Q000188:drug therapy; D008200:Lymphangiectasis / Q000151:congenital* / Q000000981:diagnostic imaging / Q000188:drug therapy; D008220:Lymphography
chemical_list: D003287:Contrast Media; D004998:Ethiodized Oil