title: Enoxaparin-induced hemorrhagic bullous dermatosis in a leprosy patient.
abstract: Enoxaparin is a low-molecular-weight heparin that has been used widely to prevent and treat thromboembolic disorders for at least 30 years. The most common adverse skin reactions to enoxaparin are ecchymosis and skin necrosis due to vasculitis, urticaria, angioedema and erythema. Side effects from heparin administration are rare and usually located at the injection site. However, recent reports have suggested that they can also occur at a distance from the site of injection. Moreover, the etiopathogenesis has not been fully explained. In this article, we present a case of hemorrhagic bullous dermatosis associated with enoxaparin for the treatment of ischemic heart disease that developed in a patient with a past history of lepromatous leprosy.
authors.affiliation: Department of Dermatology, Balikesir University Medical Faculty , Balikesir , Turkey and.
authors.forename: Savaş
authors.initials: S
authors.lastname: Öztürk
authors.forename: Ilkay
authors.initials: I
authors.lastname: Can
authors.forename: Ilker
authors.initials: I
authors.lastname: Erden
authors.forename: Hadice
authors.initials: H
authors.lastname: Akyol
authors.forename: Ozgen Aslan
authors.initials: OA
authors.lastname: Solmaz
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects*; D017984:Enoxaparin / Q000009:adverse effects*; D006801:Humans; D007918:Leprosy / Q000150:complications*; D008297:Male; D017202:Myocardial Ischemia / Q000150:complications / Q000188:drug therapy*; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000150:complications
chemical_list: D000925:Anticoagulants; D017984:Enoxaparin
keywords: Dermatosis; enoxaparin; hemorrhagic bullea