title: Negative emotional stimulation decreases respiratory sensory gating in healthy humans.
abstract: We tested the hypothesis that negative emotions decrease the respiratory-related evoked potentials (RREP) sensory gating (RSG). RREP were elicited by paired inspiratory occlusions. RSG was calculated as the difference in the averaged RREP peak N1 amplitude between the second (S2) and the first occlusion (S1). RSG was compared between unpleasant and neutral emotional conditions elicited by viewing affective pictures from the IAPS system in thirteen healthy adults. Results are expressed as median [min; max]. Compared to neutral pictures, viewing unpleasant pictures decreased the RREP N1(S1) amplitude (-3.37 μV [-4.62; -1.37] versus -4.59 μV [-6.08; -1.36]; p=0.017) but not the RREP N1(S2) amplitude (-0.26 [-3.24; 2.36] versus -0.7 [-1.54; 3.6]; p = 0.68), and reduced the difference score S2-S1 (3.73 μV [0; 5.82] versus 4.79 μV [3; 6.2]; p = 0.038). We concluded that a negative emotional stimulation could attract subject's attention to the detriment of the respiratory sensory inputs and produced an overall decrease in the RSG. This latter finding might participate in an over-perception of repeatedly presented respiratory stimuli.
authors.affiliation: Department of Physiological Sciences, University of Florida, PO Box 100144, Gainesville, FL 32610, USA; AP-HP, Groupe Hospitalier Pitié-Salpêtrière Charles Foix, Service de Pneumologie et Réanimation Médicale, 47-83 boulevard de l'hôpital, F-75013 Paris, France; Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1158, Neurophysiologie Respiratoire Expérimentale et Clinique, F-75005 Paris, France; INSERM, UMR_S 1158, Neurophysiologie Respiratoire Expérimentale et Clinique, F-75005 Paris, France. Electronic address: cecile.chenivesse@psl.aphp.fr.
authors.forename: Cecile
authors.initials: C
authors.lastname: Chenivesse
authors.affiliation: Department of Occupational Therapy, College of Medicine, and Healthy Ageing Research Center, Chang Gung University, 259 Wenhwa 1st Road, Taoyuan, Taiwan. Electronic address: chanp@mail.cgu.edu.tw.
authors.forename: Pei-Ying
authors.initials: PY
authors.lastname: Chan
authors.affiliation: Department of Physiological Sciences, University of Florida, PO Box 100144, Gainesville, FL 32610, USA. Electronic address: hwtsai@ufl.edu.
authors.forename: Hsiu-Wen
authors.initials: HW
authors.lastname: Tsai
authors.affiliation: Department of Speech Language and Hearing Sciences, University of Florida, PO Box 117420, Gainesville, FL 32611, USA. Electronic address: kwheeler@ufl.edu.
authors.forename: Karen
authors.initials: K
authors.lastname: Wheeler-Hegland
authors.affiliation: Department of Physiological Sciences, University of Florida, PO Box 100144, Gainesville, FL 32610, USA. Electronic address: epearson@ufl.edu.
authors.forename: Erin
authors.initials: E
authors.lastname: Silverman
authors.affiliation: Research group on Health Psychology, University of Leuven, Tiensestraat 102, B-3000 Leuven, Belgium. Electronic address: andreas.vonleupoldt@ppw.kuleuven.be.
authors.forename: Andreas
authors.initials: A
authors.lastname: von Leupoldt
authors.affiliation: AP-HP, Groupe Hospitalier Pitié-Salpêtrière Charles Foix, Service de Pneumologie et Réanimation Médicale, 47-83 boulevard de l'hôpital, F-75013 Paris, France; Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1158, Neurophysiologie Respiratoire Expérimentale et Clinique, F-75005 Paris, France; INSERM, UMR_S 1158, Neurophysiologie Respiratoire Expérimentale et Clinique, F-75005 Paris, France. Electronic address: thomas.similowski@psl.aphp.fr.
authors.forename: Thomas
authors.initials: T
authors.lastname: Similowski
authors.affiliation: Department of Physiological Sciences, University of Florida, PO Box 100144, Gainesville, FL 32610, USA. Electronic address: pdavenpo@ufl.edu.
authors.forename: Paul
authors.initials: P
authors.lastname: Davenport
mesh_terms: D000328:Adult; D001921:Brain / Q000502:physiology*; D004569:Electroencephalography; D004644:Emotions / Q000502:physiology*; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010775:Photic Stimulation; D012119:Respiration; D055139:Sensory Gating / Q000502:physiology*; D013147:Spirometry; D014796:Visual Perception / Q000502:physiology*; D055815:Young Adult
keywords: Dyspnea; Emotion; International affective picture system; Respiratory related evoked potential; Respiratory sensation; Sensory gating