title: Prospective, Multicenter Evaluation of Trabecular Metal-Enhanced Titanium Dental Implants Placed in Routine Dental Practices: 1-Year Interim Report From the Development Period (2010 to 2011).
abstract: BACKGROUND
  A prospective, multicenter study is currently evaluating a novel titanium implant with a highly porous tantalum midsection (tantalum material [TM]) placed in an uncontrolled patient population.
  
  
  OBJECTIVE
  Interim 1-year results from the development period (2010-2011) are reported.
  
  
  METHODS
  Investigators in 22 clinical sites located in five European countries randomly selected and treated partially edentulous patients in accordance with the implant's instructions for use and the investigators' professional judgments. Oversight was provided by the local institutional review boards. Subjects were treated with 1 to 2 TM dental implants in maxillary or mandibular location(s).
  
  
  RESULTS
  To date, 105 patients with 57 maxillary and 88 mandibular implants have completed 1 year of clinical monitoring. Within this interim group, 28 patients had concomitant health conditions that may elevate risks for long-term crestal bone loss and/or implant survival. Three implants failed due to local or systemic infection, and four implants failed to integrate. Cumulative implant survival was 95.2% (n = 138/145) with 0.43 ± 0.57 mm of mean marginal bone loss in this interim group.
  
  
  CONCLUSIONS
  TM dental implants were clinically effective under various clinical conditions in an uncontrolled patient population with and without concomitant health conditions.
authors.affiliation: Private Practice in Periodontology and Oral Implantology, Forcheim, Germany.
authors.forename: Markus
authors.initials: M
authors.lastname: Schlee
authors.affiliation: Faculty of Dentistry, Complutense University, Madrid, Spain.|Private Practice in Prosthodontics and Oral Implantology, Madrid, Spain.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Pradies
authors.affiliation: Private Practice in Periodontology and Oral Implantology, Chemnitz, Germany.
authors.forename: Wolf-Ullrich
authors.initials: WU
authors.lastname: Mehmke
authors.affiliation: Private Practice in Oral Surgery, Periodontology, and Oral Implantology, Bordeaux, France.
authors.forename: Arnaud
authors.initials: A
authors.lastname: Beneytout
authors.affiliation: Private Practice in Oral Implantology and Periodontology, Overath, Germany.
authors.forename: Matthais
authors.initials: M
authors.lastname: Stamm
authors.affiliation: Private Practice in Oral Surgery, Ponferrada, Leon, Spain.
authors.forename: Ramón Gómez
authors.initials: RG
authors.lastname: Meda
authors.affiliation: Private Practice in Esthetic Dentistry, Periodontology, and Oral Implantology, Baden-Baden, Germany.
authors.forename: Torsten
authors.initials: T
authors.lastname: Kamm
authors.affiliation: Private Practice in Periodontology and Oral Implantology, La Rochelle, France.
authors.forename: Francois
authors.initials: F
authors.lastname: Poiroux
authors.affiliation: Private Practice in General Dentistry and Oral Implantology, Neu-Isenburg, Germany.
authors.forename: Franz
authors.initials: F
authors.lastname: Weinlich
authors.affiliation: Oral Surgery, Implantology and Periodontology, University of Léon, Leon, Spain.
authors.forename: Mariano
authors.initials: M
authors.lastname: del Canto Pingarron
authors.affiliation: Private Practice in Periodontology and Oral Implantology, Houilles, France.
authors.forename: Eric
authors.initials: E
authors.lastname: Crichton
authors.affiliation: Private Practice in Oral Implantology, Tarare, France.
authors.forename: Jean-Baptiste
authors.initials: JB
authors.lastname: Poulet
authors.affiliation: Periodontology and Implantology, Montpellier University, Béziers, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Bousquet
mesh_terms: D000328:Adult; D000368:Aged; D003758:Dental Implantation, Endosseous / Q000379:methods*; D015921:Dental Implants; D017267:Dental Prosthesis Design; D019232:Dental Restoration Failure; D005060:Europe; D005260:Female; D005792:General Practice, Dental; D006801:Humans; D007576:Jaw, Edentulous, Partially / Q000534:rehabilitation; D008297:Male; D008875:Middle Aged; D016062:Porosity; D011446:Prospective Studies; D012307:Risk Factors; D013635:Tantalum; D014025:Titanium; D016896:Treatment Outcome
chemical_list: D015921:Dental Implants; D013635:Tantalum; D014025:Titanium
keywords: osseoincorporation; titanium-tantalum implant; trabecular metal