title: Unusual antibiotic presence in gym trained subjects with food intolerance; a case report.
abstract: BACKGROUND
  Great interest is raising in food intolerances due to the lack, in many cases, of a particular sensitizing agent.
  
  
  OBJECTIVE
  We investigated the serum level of possible new haptens in 15 heavy meat consumers for sport fitness affected by various kinds of food intolerance and who had ever been administered antibiotics in their life for clinical problems.
  
  
  METHODS
  Forty ml of blood were drawn from each patient and analyzed, by means of an ELISA test, in order to possibly identify the presence of an undue contaminant with hapten properties.
  
  
  RESULTS
  Four out of fifteen subjects (26%) showed a serum oxytetracycline amount > 6 ng/g (which is considered the safety limit), 10 of 15 (66%) a serum doxycycline amount > of 6 ng/g and 3 out of 15 (30%) subjects had high serum level of both molecules.
  
  
  CONCLUSIONS
  Although a direct ratio between body antibiotics remnant storage in the long run and chronic gut dysfunctions and/or food allergy did not reached the evidence yet, the blood traces of these compounds in a food intolerant otherwise healthy population might be considered the preliminary putative step of a sensitizing pathway. Our next goals foresee a deeper insight into the sensitizing trigger from human chronic antibiotic exposure via the zootechnical delivery of poultry food.
authors.affiliation: Poliambulatorio del Secondo Parere. Department of Consultation and Coordination. Viale Reiter 14. 41225 Modena. Italy.. alessandro811@hotmail.it.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Di Cerbo
authors.affiliation: Via Euganea villa 1 - villa di teolo. 35037 Padova. Italy.. Sergio.canello.5@facebook.com.
authors.forename: Sergio
authors.initials: S
authors.lastname: Canello
authors.affiliation: Via Alfonso Chierici 1. 42121 Reggio Emilia. Italy.. gianandrea.guidetti@gmail.com.
authors.forename: Gianandrea
authors.initials: G
authors.lastname: Guidetti
authors.affiliation: Azienda Ospedaliero-Universitaria Policlinico di Modena. Surgery and Surgical Specialties department. University of Modena and Reggio Emilia. Via del Pozzo 71. 41124 Modena. Italy.. Carmen.laurino@hotmail.it.
authors.forename: Carmen
authors.initials: C
authors.lastname: Laurino
authors.affiliation: Azienda Ospedaliero-Universitaria Policlinico di Modena. Surgery and Surgical Specialties department. University of Modena and Reggio Emilia. Via del Pozzo 71. 41124 Modena. Italy.. palmieri@unimo.it.
authors.forename: Beniamino
authors.initials: B
authors.lastname: Palmieri
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000097:blood*; D004318:Doxycycline / Q000097:blood*; D005260:Female; D005512:Food Hypersensitivity / Q000097:blood*; D006801:Humans; D008297:Male; D010118:Oxytetracycline / Q000097:blood*
chemical_list: D000900:Anti-Bacterial Agents; D004318:Doxycycline; D010118:Oxytetracycline