title: Cardiovascular disease associated with the human immunodeficiency virus: an update.
abstract: With the advent of increasingly available antiretroviral therapy (ART), the life expectancy of HIV-infected persons is increasing. As they age, HIV-infected persons have increased propensity to typical diseases of aging including cardiovascular disease and accelerated atherosclerosis. The pathogenesis of HIV-associated atherosclerosis is complex and involves a state of chronic inflammation, exposure to traditional risk factors, and metabolic side effects of ART. Treatment of HIV-associated atherosclerosis should include special attention to drug-drug interactions and is best accomplished by a multidisciplinary team experienced in the care of HIV-infected persons.
authors.affiliation: Department of Medicine, Johns Hopkins Hospital, Baltimore, MD, USA.
authors.forename: Thomas S
authors.initials: TS
authors.lastname: Metkus
authors.forename: Todd T
authors.initials: TT
authors.lastname: Brown
authors.forename: Wendy S
authors.initials: WS
authors.lastname: Post