title: Chemical profile by LC-MS/MS, GC/MS and antioxidant activities of the essential oils and crude extracts of two Euphorbia species.
abstract: In this study, it was aimed to investigate the chemical composition and antioxidant activities of two Euphorbia species. The major component of the fatty acid compositions obtained from the petroleum ether extracts was identified as palmitic acid for Euphorbia gaillardotii and Euphorbia macroclada. The main constituents of the essential oils were identified as arachidic acid for E. gaillardotii and tetratetracontane for E. macroclada. Among the 27 studied compounds, hesperidin, rutin, hyperoside and quinic, malic, gallic and tannic acids were found to be the most abundant compounds in the two Euphorbia species. The methanol extracts of E. gaillardotii and E. macroclada showed strong antioxidant activity in all tested methods. Particularly, IC50 values of E. macroclada methanol extract that was the richest in terms of total phenolic-flavonoid contents were found to be lower than α-tocopherol and butylated hydroxytoluene in β-carotene bleaching, 2,2-diphenyl-1-picrylhydrazyl free and ABTS cation radical scavenging methods.
authors.affiliation: a Department of Pharmacognosy , Faculty of Pharmacy, Dicle University , 21280 Diyarbakir , Turkey.
authors.forename: Abdulselam
authors.initials: A
authors.lastname: Ertas
authors.forename: Mustafa Abdullah
authors.initials: MA
authors.lastname: Yilmaz
authors.forename: Mehmet
authors.initials: M
authors.lastname: Firat
mesh_terms: D000975:Antioxidants / Q000737:chemistry*; D028481:Euphorbia / Q000737:chemistry*; D005227:Fatty Acids / Q000737:chemistry; D005419:Flavonoids / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D009822:Oils, Volatile / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry*; D010938:Plant Oils / Q000737:chemistry*; D053719:Tandem Mass Spectrometry
chemical_list: D000975:Antioxidants; D005227:Fatty Acids; D005419:Flavonoids; D009822:Oils, Volatile; D010636:Phenols; D010936:Plant Extracts; D010938:Plant Oils
keywords: Euphorbia gaillardotii; Euphorbia macroclada; GC/MS; LC–MS/MS; antioxidant activity