title: [Analysis of picric acid and picramic acid in water samples by ultra performance hydrophilic interaction chromatography-tandem mass spectrometry].
abstract: An ultra performance liquid chromatography/tandem mass spectrometry (UPLC-MS/ MS) method was developed for the determination of picric acid and its reductive transformation product picramic acid in aqueous samples. A hydrophilic interaction liquid chromatography (HILIC) column (Acquity UPLC BEH HILIC; 100 mm x 2.1 mm, 1.7 microm) was used for the separation. Surface water samples could be injected into the UPLC system just after being filtered through a 0.2 microm membrane. The satisfactory recoveries of picric acid and picramic acid were in the range of 89% - 107%. Waste water samples were purified by solid phase extraction (SPE), and then were analyzed. The recoveries of picric acid and picramic acid in waste water were 72%-101%. The reproducibility of the method was good with the RSDs of 4.9% - 14.7%. The limits of detection (LODs) of picric acid and picramic acid were 0.1 microg/L and 0.3 microg/L, respectively. This proposed method is rapid, highly specific and suitable for the confirmation and quantitative determination of picric acid and picramic acid in surface water and waste water.
authors.forename: Feizhong
authors.initials: F
authors.lastname: Qian
authors.forename: Libo
authors.initials: L
authors.lastname: Zhu
authors.forename: Nengbin
authors.initials: N
authors.lastname: Xu
authors.forename: Jiayong
authors.initials: J
authors.lastname: Feng
authors.forename: Zhengfang
authors.initials: Z
authors.lastname: Hong
authors.forename: Lihong
authors.initials: L
authors.lastname: Xu
authors.forename: Zhongquan
authors.initials: Z
authors.lastname: Chen
authors.forename: Shengle
authors.initials: S
authors.lastname: Wang