title: Bilateral Achilles Tendon Ruptures Associated With Ciprofloxacin Use in the Setting of Minimal Change Disease: Case Report and Review of the Literature.
abstract: Fluoroquinolones are widely used antibiotics; however, numerous side effects have been reported in published studies, including a spectrum of tendinopathies, affecting numerous anatomic sites. Several risk factors have been identified, including advanced age (>60 years), corticosteroid use, renal failure or dialysis, female sex, and nonobesity. We present the case of an elderly male with minimal change disease treated with glucocorticoids and acute kidney injury, who sustained spontaneous nontraumatic bilateral Achilles tendon tears 4 days after initiating ciprofloxacin.
authors.affiliation: Resident, Division of Orthopaedic Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
authors.forename: Firas
authors.initials: F
authors.lastname: Kawtharani
authors.affiliation: Resident, Division of Orthopaedic Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon. Electronic address: km34@aub.edu.lb.
authors.forename: Karim Z
authors.initials: KZ
authors.lastname: Masrouha
authors.affiliation: Clinical Senior Lecturer, Division of Orthopaedic Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
authors.forename: Nadim
authors.initials: N
authors.lastname: Afeiche
mesh_terms: D000125:Achilles Tendon / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000473:pathology; D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000009:adverse effects* / Q000627:therapeutic use; D003428:Cross Infection / Q000188:drug therapy; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009402:Nephrosis, Lipoid / Q000150:complications / Q000188:drug therapy*; D011014:Pneumonia / Q000188:drug therapy; D012421:Rupture; D013708:Tendon Injuries / Q000139:chemically induced*
chemical_list: D000900:Anti-Bacterial Agents; D005938:Glucocorticoids; D002939:Ciprofloxacin
keywords: Achilles tendon; minimal change disease; quinolone; rupture