title: Assembly and molecular order of two-dimensional peptoid nanosheets through the oil-water interface.
abstract: Peptoid nanosheets are a recently discovered class of 2D nanomaterial that form from the self-assembly of a sequence-specific peptoid polymer at an air-water interface. Nanosheet formation occurs first through the assembly of a peptoid monolayer and subsequent compression into a bilayer structure. These bilayer materials span hundreds of micrometers in lateral dimensions and have the potential to be used in a variety of applications, such as in molecular sensors, artificial membranes, and as catalysts. This paper reports that the oil-water interface provides another opportunity for growth of these unique and highly ordered peptoid sheets. The monolayers formed at this interface are found through surface spectroscopic measurements to be highly ordered and electrostatic interactions between the charged moieties, namely carboxylate and ammonium residues, of the peptoid are essential in the ability of these peptoids to form ordered nanosheets at the oil-water interface. Expanding the mechanism of peptoid nanosheet formation to the oil-water interface and understanding the crucial role of electrostatic interactions between peptoid residues in nanosheet formation is essential for increasing the complexity and functionality of these nanomaterials.
authors.affiliation: Department of Chemistry, University of Oregon, Eugene, OR 97403; and.
authors.forename: Ellen J
authors.initials: EJ
authors.lastname: Robertson
authors.affiliation: Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.
authors.forename: Gloria K
authors.initials: GK
authors.lastname: Oliver
authors.affiliation: Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.
authors.forename: Menglu
authors.initials: M
authors.lastname: Qian
authors.affiliation: Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.
authors.forename: Caroline
authors.initials: C
authors.lastname: Proulx
authors.affiliation: Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 richmond@uoregon.edu rnzuckermann@lbl.gov.
authors.forename: Ronald N
authors.initials: RN
authors.lastname: Zuckermann
authors.affiliation: Department of Chemistry, University of Oregon, Eugene, OR 97403; and richmond@uoregon.edu rnzuckermann@lbl.gov.
authors.forename: Geraldine L
authors.initials: GL
authors.lastname: Richmond
mesh_terms: D008958:Models, Molecular; D053758:Nanoparticles / Q000737:chemistry*; D009821:Oils / Q000737:chemistry*; D034444:Peptoids / Q000737:chemistry*; D011312:Pressure; D013057:Spectrum Analysis; D014732:Vibration; D014867:Water / Q000737:chemistry*
chemical_list: D009821:Oils; D034444:Peptoids; D014867:Water
keywords: biomimetic polymers; liquid surfaces; peptoid assembly; protein mimetic materials; vibrational sum frequency spectroscopy