title: Hydroalumination-triggered cyclization of silylated 1,3-dien-5-ynes to polysubstituted benzenes.
abstract: Regiocontrolled synthesis of polysubstituted benzenes from silylated 1,3-dien-5-ynes has been achieved by using diisobutylaluminum hydride (DIBAL-H). Hydroalumination of the alkyne moiety with DIBAL-H triggers the aromatic cyclization, which usually proceeds without rearrangement and loss of the existing substituents. The related unusual cyclizations to different types of polysubstituted benzenes are also described.
authors.affiliation: Department of Applied Chemistry, Graduate School of Science and Engineering, Saitama University , 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan.
authors.forename: Hidenori
authors.initials: H
authors.lastname: Kinoshita
authors.forename: Takayuki
authors.initials: T
authors.lastname: Tohjima
authors.forename: Katsukiyo
authors.initials: K
authors.lastname: Miura