title: Beak and feather disease virus: correlation between viral load and clinical signs in wild Cape parrots (Poicepahlus robustus) in South Africa.
abstract: Psittacine beak and feather disease (PBFD), the most prevalent viral disease affecting psittacines, is caused by beak and feather disease virus (BFDV). This study assessed viral load using qPCR in a wild Cape parrot population affected by PBFD and compared it to overall physical condition based on clinical signs attributable to PBFD. A significant inverse correlation between viral load and overall physical condition was found, which confirmed that clinical signs may confidently be used to diagnose the relative severity of BFDV infections in wild populations. This is the first assessment of BFDV viral load in a wild psittacine population.
authors.affiliation: Biopharming Research Unit, Department of Molecular and Cell Biology, University of Cape Town, Rondebosch, 7701, South Africa.
authors.forename: Guy L
authors.initials: GL
authors.lastname: Regnard
authors.forename: Rutledge S
authors.initials: RS
authors.lastname: Boyes
authors.forename: Rowan O
authors.initials: RO
authors.lastname: Martin
authors.forename: Inga I
authors.initials: II
authors.lastname: Hitzeroth
authors.forename: Edward P
authors.initials: EP
authors.lastname: Rybicki
mesh_terms: D000818:Animals; D001715:Bird Diseases / Q000453:epidemiology / Q000473:pathology / Q000821:virology*; D018173:Circoviridae Infections / Q000453:epidemiology / Q000473:pathology / Q000662:veterinary* / Q000821:virology; D017925:Circovirus / Q000302:isolation & purification*; D005260:Female; D008297:Male; D010311:Parrots; D013019:South Africa / Q000453:epidemiology; D019562:Viral Load