title: Anaplastic myeloma presenting as mandibular swelling: Diagnosis by cytology.
abstract: Multiple myeloma is a disease resulting from clonal proliferation of plasma cells. A disease of the elderly, jaw lesions are seen in 14% of patients affected with myeloma. Rarely the oral and maxillofacial lesions can be the first manifestation of the disease. We report the case of a 75-year-old man who presented with mandibular swelling. Fine-needle aspiration cytology was done from the swelling and smears were suggestive of anaplastic myeloma, which is a rare and aggressive variant of myeloma. The diagnosis of a plasmacytoma was confirmed by biopsy. Further workup of the patient revealed osteolytic lesions in skull, M band in electrophoresis and evidence of renal failure. Peripheral smear and bone marrow findings were also consistent with myeloma.
authors.affiliation: Department of Pathology, Government Medical College, Kottayam, Kerala, India.
authors.forename: K
authors.initials: K
authors.lastname: Subitha
authors.affiliation: Department of Pathology, Government Medical College, Kottayam, Kerala, India.
authors.forename: Thampy
authors.initials: T
authors.lastname: Renu
authors.affiliation: Department of Pathology, Government Medical College, Kottayam, Kerala, India.
authors.forename: Pothen
authors.initials: P
authors.lastname: Lillykutty
authors.affiliation: Department of Pathology, Government Medical College, Kottayam, Kerala, India.
authors.forename: V
authors.initials: V
authors.lastname: Letha
keywords: Anaplastic; cytology; mandibular swelling; myeloma