title: Bloodstream Infections among Solid Organ Transplant Recipients: Eight Years' Experience from a Turkish University Hospital.
abstract: BACKGROUND
  Bloodstream infections (BSI) are frequently seen after solid organ transplantation. The incidence of bloodstream infections differs among the types of transplantation. The microbiological features and antimicrobial resistance patterns change from centre to centre.
  
  
  OBJECTIVE
  To evaluate the incidence and spectrum of aetiological agents of bloodstream infections among solid organ transplantation recipients.
  
  
  METHODS
  Retrospective descriptive study.
  
  
  METHODS
  Medical records of solid organ transplant recipients in the period between January 1(st) 2004 and August 15(th) 2012 were assessed retrospectively. The study population comprised 927 (64 heart, 556 kidney, 307 liver) consecutive recipients. Bloodstream infections were divided into three groups according to the onset time of bloodstream infections after transplantation: early, mid-term and late. The incidence and microbiological features of bloodstream infections were evaluated.
  
  
  RESULTS
  The number of bloodstream infection episodes was 317 in 191 recipients which was distributed as 228 (72%) in liver, 70 (22%) in kidney and 19 (6%) in heart transplantation. Ninety-eight 98 (30.9%) of the episodes were diagnosed within the early period, 134 (42.3%) within the mid-term and 85 (26.8%) in the late period. Early and mid-term bloodstream infections were seen statistically more often in liver than in kidney or heart transplantation (p=0.01 and p=0.031, respectively). Late bloodstream infections were also common in liver transplant recipients which was not statistically significant (p=0.229).
  
  
  CONCLUSIONS
  Liver transplant recipients are at the highest risk for developing BSI after transplantation in early, mid-term and late periods.
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Başkent University Faculty of Medicine, Ankara, Turkey.
authors.forename: Ayşegül
authors.initials: A
authors.lastname: Yeşilkaya
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Başkent University Faculty of Medicine, Ankara, Turkey.
authors.forename: Ozlem Kurt
authors.initials: OK
authors.lastname: Azap
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Başkent University Faculty of Medicine, Ankara, Turkey.
authors.forename: Melike Hamiyet
authors.initials: MH
authors.lastname: Demirkaya
authors.affiliation: Department of Statistics and Computer Science, Başkent University Faculty of Science and Letters, Ankara, Turkey.
authors.forename: Mehtap Akçıl
authors.initials: MA
authors.lastname: Ok
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Başkent University Faculty of Medicine, Ankara, Turkey.
authors.forename: Hande
authors.initials: H
authors.lastname: Arslan
authors.affiliation: Department of General Surgery, Başkent University Faculty of Medicine, Ankara, Turkey.
authors.forename: Aydıncan
authors.initials: A
authors.lastname: Akdur
keywords: Bloodstream infection; Turkey; organ transplantation