title: Viral RNA recognition by the Drosophila small interfering RNA pathway.
abstract: Viral RNA is a common activator of antiviral responses. In this review, we dissect the mechanism of viral RNA recognition by the small interfering RNA pathway in Drosophila melanogaster. This antiviral response in fruit flies can help understand general principles of nucleic acid recognition.
authors.affiliation: Department of Biochemistry and Immunology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
authors.forename: Zamira Guerra
authors.initials: ZG
authors.lastname: Soares
authors.affiliation: Department of Biochemistry and Immunology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
authors.forename: André Nicolau Aquime
authors.initials: AN
authors.lastname: Gonçalves
authors.affiliation: Department of Biochemistry and Immunology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
authors.forename: Karla Pollyanna Vieira
authors.initials: KP
authors.lastname: de Oliveira
authors.affiliation: Department of Biochemistry and Immunology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. Electronic address: jtm@ufmg.br.
authors.forename: João Trindade
authors.initials: JT
authors.lastname: Marques
mesh_terms: D000818:Animals; D004330:Drosophila / Q000235:genetics* / Q000276:immunology* / Q000821:virology; D005786:Gene Expression Regulation; D054884:Host-Pathogen Interactions; D034622:RNA Interference; D012330:RNA, Double-Stranded / Q000235:genetics / Q000276:immunology; D034741:RNA, Small Interfering / Q000235:genetics*; D012367:RNA, Viral / Q000235:genetics* / Q000276:immunology*
chemical_list: D012330:RNA, Double-Stranded; D034741:RNA, Small Interfering; D012367:RNA, Viral
keywords: Drosophila melanogaster; RNA interference; Small interfering RNA; Viral infection; dsRNA