title: Role of multi-detector computed tomography for biliary complications after liver transplantation.
abstract: OBJECTIVE
  To investigate the diagnostic performance of multi-detector computed tomography (MDCT) in detecting biliary complications after orthotopic liver transplantation (OLT).
  
  
  METHODS
  Eighty-three consecutive OLT recipients, who presented with clinical or biochemical signs of biliary complications, underwent MDCT examination. Two experienced radiologists assessed MDCT images in consensus to determine biliary complications. Final confirmation was based on percutaneous transhepatic cholangiography or endoscopic retrograde cholangiography in 58 patients, surgery in four patients, liver biopsy in 10, and clinical and sonography follow-up in 11 patients.
  
  
  RESULTS
  Biliary complications were eventually confirmed in 62 of 83 patients (74.7%), including anastomotic biliary strictures in 32, nonanastomotic biliary strictures in 21, biliary stones in nine (5 with biliary strictures), anastomotic bile leak in five, and biloma in six (all with nonanastomotic strictures, and 2 with biligenic hepatic abscess). Twenty-one patients had no detection of biliary complications. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of MDCT for detecting biliary strictures were 90.6%, 86.7%, 89.2%, 92.3% and 83.9%, respectively. For detecting biliary stones, anastomotic bile leak and biloma, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of MDCT were all 100%.
  
  
  CONCLUSIONS
  MDCT is a useful screening tool for detecting biliary complications after OLT.
authors.affiliation: Xiao-Chun Meng, Wen-Sou Huang, Pei-Yi Xie, Xiu-Zhen Chen, Ming-Yue Cai, Hong Shan, Kang-Shun Zhu, Department of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China.
authors.forename: Xiao-Chun
authors.initials: XC
authors.lastname: Meng
authors.affiliation: Xiao-Chun Meng, Wen-Sou Huang, Pei-Yi Xie, Xiu-Zhen Chen, Ming-Yue Cai, Hong Shan, Kang-Shun Zhu, Department of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China.
authors.forename: Wen-Sou
authors.initials: WS
authors.lastname: Huang
authors.affiliation: Xiao-Chun Meng, Wen-Sou Huang, Pei-Yi Xie, Xiu-Zhen Chen, Ming-Yue Cai, Hong Shan, Kang-Shun Zhu, Department of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China.
authors.forename: Pei-Yi
authors.initials: PY
authors.lastname: Xie
authors.affiliation: Xiao-Chun Meng, Wen-Sou Huang, Pei-Yi Xie, Xiu-Zhen Chen, Ming-Yue Cai, Hong Shan, Kang-Shun Zhu, Department of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China.
authors.forename: Xiu-Zhen
authors.initials: XZ
authors.lastname: Chen
authors.affiliation: Xiao-Chun Meng, Wen-Sou Huang, Pei-Yi Xie, Xiu-Zhen Chen, Ming-Yue Cai, Hong Shan, Kang-Shun Zhu, Department of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China.
authors.forename: Ming-Yue
authors.initials: MY
authors.lastname: Cai
authors.affiliation: Xiao-Chun Meng, Wen-Sou Huang, Pei-Yi Xie, Xiu-Zhen Chen, Ming-Yue Cai, Hong Shan, Kang-Shun Zhu, Department of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Shan
authors.affiliation: Xiao-Chun Meng, Wen-Sou Huang, Pei-Yi Xie, Xiu-Zhen Chen, Ming-Yue Cai, Hong Shan, Kang-Shun Zhu, Department of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China.
authors.forename: Kang-Shun
authors.initials: KS
authors.lastname: Zhu
mesh_terms: D000328:Adult; D000368:Aged; D057868:Anastomotic Leak / Q000000981:diagnostic imaging* / Q000209:etiology / Q000601:surgery; D001706:Biopsy; D002760:Cholangiopancreatography, Endoscopic Retrograde; D002769:Cholelithiasis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000601:surgery; D002779:Cholestasis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000601:surgery; D003251:Constriction, Pathologic; D005260:Female; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography; D011237:Predictive Value of Tests; D016896:Treatment Outcome
keywords: Biliary; Complications; Computed tomography; Liver; Transplantation