title: Usefulness of sugammadex in a patient with Becker muscular dystrophy and dilated cardiomyopathy.
abstract: A 54-year-old patient with Becker muscular dystrophy and dilated cardiomyopathy underwent laparoscopic cholecystectomy under total intravenous anesthesia. Muscle relaxation was induced by rocuronium (0.4 mg/kg body weight) under train-of-four (TOF) ratio monitoring. The TOF ratio was 0 at intubation, and 0.2 at the end of surgery. Residual muscle relaxant activity was successfully reversed by sugammadex (2 mg/kg body weight) without any hemodynamic adverse effects (TOF ratio 1.0 at extubation). The clinical and hemodynamic findings suggest that sugammadex can be safely used in patients with Becker muscular dystrophy and dilated cardiomyopathy.
authors.affiliation: Department of Anesthesiology and Critical Care, Kyushu University Hospital, Fukuoka, Japan.
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Shimauchi
authors.affiliation: Operating Rooms, Kyushu University Hospital, Fukuoka, Japan. Electronic address: keny@fukuoka-u.ac.jp.
authors.forename: Ken
authors.initials: K
authors.lastname: Yamaura
authors.affiliation: Department of Anesthesiology and Critical Care, Kyushu University Hospital, Fukuoka, Japan.
authors.forename: Sayaka
authors.initials: S
authors.lastname: Sugibe
authors.affiliation: Department of Anesthesiology and Critical Care, Kyushu University Hospital, Fukuoka, Japan.
authors.forename: Sumio
authors.initials: S
authors.lastname: Hoka
mesh_terms: D002311:Cardiomyopathy, Dilated / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D020388:Muscular Dystrophy, Duchenne / Q000503:physiopathology*; D000077122:Sugammadex; D047408:gamma-Cyclodextrins / Q000494:pharmacology*
chemical_list: D047408:gamma-Cyclodextrins; D000077122:Sugammadex
keywords: cardiomyopathy, dilated; gamma-cyclodextrins: sugammadex; myotonic dystrophy: Becker