title: Emerging issues in public health genomics.
abstract: This review highlights emerging areas of interest in public health genomics. First, we describe recent advances in newborn screening (NBS), with a focus on the practice and policy implications of current and future efforts to expand NBS programs (e.g., via next-generation sequencing). Next, we detail research findings from the rapidly progressing field of epigenetics and epigenomics, highlighting ways in which our emerging understanding in these areas could guide future intervention and research efforts in public health. We close by considering various ethical, legal, and social issues posed by recent developments in public health genomics; these include policies to regulate access to personal genomic information, the need to enhance genetic literacy in both health professionals and the public, and challenges in ensuring that the benefits (and burdens) of genomic discoveries and applications are equitably distributed. We also note needs for future genomic research that integrates across basic and social sciences.
authors.affiliation: Department of Health Behavior & Health Education University of Michigan School of Public Health.
authors.forename: J Scott
authors.initials: JS
authors.lastname: Roberts
authors.affiliation: Department of Environmental Health Sciences University of Michigan School of Public Health.
authors.forename: Dana
authors.initials: D
authors.lastname: Dolinoy
authors.affiliation: Child Health Evauation & Research Unit Division of Pediatrics University of Michigan Health System.
authors.forename: Beth
authors.initials: B
authors.lastname: Tarini
mesh_terms: D057890:Epigenomics / Q000941:ethics / Q000331:legislation & jurisprudence; D023281:Genomics / Q000941:ethics* / Q000331:legislation & jurisprudence; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D007231:Infant, Newborn; D015997:Neonatal Screening / Q000941:ethics* / Q000331:legislation & jurisprudence; D011634:Public Health / Q000941:ethics* / Q000331:legislation & jurisprudence
keywords: bioethics; epigenetics; epigenomics; health education; newborn screening