title: Evaluation of the efficiency of Trametes hirsuta for the removal of multiple pharmaceutical compounds under low concentrations relevant to the environment.
abstract: An evaluation of the efficiency of the White-rot fungi (WRF) Trametes hirsuta to remove multi-classes pharmaceutical active compounds (17 PhACs) at low and environmentally realistic concentrations (20-500 ng L(-1)) was performed. The importance of biosorption over enzymatic activity on PhACs removal was also evaluated. Results highlight the importance to consider environmentally relevant PhACs concentrations while evaluating the removal capacities of WRF in wastewaters treatment processes, as PhACs concentration strongly influence both the enzymatic activity profile and the removal efficiency. Results also show that under tested experimental conditions, laccase was the only active extracellular lignin modifying enzyme and that biosorption and possibly intracellular enzymes also contribute to the removal of some PhACs.
authors.affiliation: Department of Chemistry, Université de Sherbrooke, 2500 Boul. de l'Université, Sherbrooke (Qc) J1K 2R1, Canada.
authors.forename: Lounès
authors.initials: L
authors.lastname: Haroune
authors.affiliation: Department of Civil Engineering, Université de Sherbrooke, 2500 Boul. de l'Université, Sherbrooke (Qc) J1K 2R1, Canada.
authors.forename: Sabrina
authors.initials: S
authors.lastname: Saibi
authors.affiliation: Department of Chemistry, Université de Sherbrooke, 2500 Boul. de l'Université, Sherbrooke (Qc) J1K 2R1, Canada.
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Bellenger
authors.affiliation: Department of Civil Engineering, Université de Sherbrooke, 2500 Boul. de l'Université, Sherbrooke (Qc) J1K 2R1, Canada. Electronic address: Hubert.Cabana@USherbrooke.ca.
authors.forename: Hubert
authors.initials: H
authors.lastname: Cabana
mesh_terms: D000327:Adsorption; D000704:Analysis of Variance; D042845:Laccase / Q000378:metabolism; D008031:Lignin / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000302:isolation & purification / Q000378:metabolism*; D013056:Spectrophotometry, Ultraviolet; D055454:Trametes / Q000378:metabolism*; D014865:Waste Disposal, Fluid / Q000379:methods*; D014874:Water Pollutants, Chemical / Q000378:metabolism*; D018508:Water Purification / Q000379:methods*
chemical_list: D004364:Pharmaceutical Preparations; D014874:Water Pollutants, Chemical; D008031:Lignin; D042845:Laccase
keywords: Laccase; Lignin modifying enzymes; Pharmaceutical compounds; Trametes hirsuta; White-rot fungi