title: Almost half of women with malignant mesothelioma were exposed to asbestos at home through their husbands or sons.
abstract: BACKGROUND
  Women often develop malignant mesothelioma (MM) without occupational asbestos exposure. Northern Jutland has a high prevalence of MM due to previously high occupational exposures to asbestos. The aim of this study was to elucidate a possible domestic exposure to asbestos through first-degree relatives in women who develop MM.
  
  
  METHODS
  This was a retrospective study in women with MM of the pleura. A total of 30 women were diagnosed with and treated for MM in Northern Jutland from 1996 to 2012. In all, 24 women were included. Demographic data, subtype of MM, time from first hospital contact to diagnosis, survival and information on occupational and domestic exposure to asbestos were obtained from hospital records.
  
  
  RESULTS
  A total of 12.5% of the study population were primarily exposed to asbestos. 46% had domestic exposure to asbestos through their husbands or sons. The median age of the study population was 66.5 years. In all, 75% suffered from the epitheloid subtype, 12.5% from the biphasic and 8.4% from the sarcomatoid subtype. Time from first hospital contact to diagnosis was one month and the median survival time was 12 months. The 1- and 5- year-survival were 58% and 0%, respectively.
  
  
  CONCLUSIONS
  Nearly 50% of the women affected by MM have been domestically exposed to asbestos through first-degree relatives.
  
  
  BACKGROUND
  not relevant.
  
  
  BACKGROUND
  not relevant.
authors.affiliation: Aalborg University Hospital, 9100 Aalborg, Denmark. majsendahl@gmail.com.
authors.forename: Maja Dahl
authors.initials: MD
authors.lastname: Langhoff
authors.forename: Maren Brøndberg
authors.initials: MB
authors.lastname: Kragh-Thomsen
authors.forename: Sharleny
authors.initials: S
authors.lastname: Stanislaus
authors.forename: Ulla Møller
authors.initials: UM
authors.lastname: Weinreich
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001194:Asbestos / Q000633:toxicity*; D003718:Denmark / Q000453:epidemiology; D004781:Environmental Exposure / Q000009:adverse effects* / Q000706:statistics & numerical data; D004785:Environmental Pollutants / Q000633:toxicity*; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008175:Lung Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000401:mortality; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000401:mortality; D000086002:Mesothelioma, Malignant; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects / Q000706:statistics & numerical data; D010997:Pleural Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000401:mortality; D012189:Retrospective Studies; D018454:Spouses; D015996:Survival Rate
chemical_list: D004785:Environmental Pollutants; D001194:Asbestos