title: Acromegaly--a novel view of the patient. Polish proposals for diagnostic and therapeutic procedures in the light of recent reports.
abstract: is usually delayed and is often associated with the development of various complications causing premature mortality. In patients with hypertension, heart failure, diabetes, and arthropathy that is non-specific for age, attention should be paid to the occurrence of somatic signs of acromegaly. As a screening test, insulin-like growth factor-1 (IGF-1) concentration should be assessed. Further diagnostic and treatment procedures are possible in specialised centres. The first-line therapy is selective transsphenoidal adenomectomy. Patients with a good prognosis related to a surgical removal of the pituitary tumour should be referred only to centres experienced in performing this type of procedure, after pharmacological preparation. Other patients, and those who have not recovered after surgical treatment, should be subjected to long-term pharmacotherapy with long-acting somatostatin analogues. In each case, the complications of acromegaly should be followed-up long-term and actively treated. This proposed new recommendation should be helpful for the management of patients with acromegaly.
authors.affiliation: marek.bolanowski@umed.wroc.pl.
authors.forename: Marek
authors.initials: M
authors.lastname: Bolanowski
authors.forename: Marek
authors.initials: M
authors.lastname: Ruchała
authors.forename: Wojciech
authors.initials: W
authors.lastname: Zgliczyński
authors.forename: Beata
authors.initials: B
authors.lastname: Kos-Kudła
authors.forename: Agata
authors.initials: A
authors.lastname: Bałdys-Waligórska
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Zieliński
authors.forename: Tomasz
authors.initials: T
authors.lastname: Bednarczuk
authors.forename: Alicja
authors.initials: A
authors.lastname: Hubalewska-Dydejczyk
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Kamiński
authors.forename: Bogdan
authors.initials: B
authors.lastname: Marek
authors.forename: Jacek
authors.initials: J
authors.lastname: Daroszewski
authors.forename: Ryszard
authors.initials: R
authors.lastname: Waśko
authors.forename: Andrzej
authors.initials: A
authors.lastname: Lewiński
mesh_terms: D000172:Acromegaly / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000628:therapy*; D000315:Adrenalectomy / Q000379:methods; D018491:Dopamine Agonists / Q000627:therapeutic use; D019382:Human Growth Hormone / Q000627:therapeutic use; D006801:Humans; D010911:Pituitary Neoplasms / Q000150:complications; D011044:Poland; D011379:Prognosis
chemical_list: D018491:Dopamine Agonists; D019382:Human Growth Hormone