title: Rewiring the niche: sympathetic neuropathy drives malignant niche transformation.
abstract: In recent years, it has become increasingly evident that hematological malignancies can alter their microenvironment, but the therapeutic implications of these changes and potential targets have not been well characterized. Recent findings now describe how sympathetic neuropathy can drive malignant transformation of the hematopoietic stem cell niche in hematopoietic malignancies.
authors.affiliation: Division of Hematologic Malignancies and Cellular Therapy, Duke University, Durham, NC 27710, USA.
authors.forename: Trevor
authors.initials: T
authors.lastname: Price
authors.affiliation: Division of Hematologic Malignancies and Cellular Therapy, Duke University, Durham, NC 27710, USA. Electronic address: dorothy.sipkins@duke.edu.
authors.forename: Dorothy A
authors.initials: DA
authors.lastname: Sipkins
mesh_terms: D000818:Animals; D001342:Autonomic Nervous System Diseases / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D006412:Hematopoietic Stem Cells / Q000473:pathology; D006801:Humans; D051379:Mice; D055153:Stem Cell Niche