title: Effect of premenstrual stress on autonomic function.
abstract: BACKGROUND
  Premenstrual syndrome is a psychoneuro endocrine stress related disorder.
  
  
  OBJECTIVE
  To study the effect of premenstrual stress on autonomic function.
  
  
  METHODS
  Study of autonomic function basal heart rate, basal blood pressure, systolic & diastolic response to cold stimulus was carried out in 80 Eumenorrheic females age between 18-25 yrs. during premenstrual & post menstrual phase. Subjects were divided in two groups control (n-40), premenstrual syndrome group (n-40) based on presence of symptoms.
  
  
  RESULTS
  Increased autonomic nervous activity with significantly increased heart rate, blood pressure, systolic & diastolic response to cold stimulus was observed during premenstrual phase. Difference of mean of autonomic function in pre and post menstrual phase in premenstrual syndrome group was significantly higher than control.
  
  
  CONCLUSIONS
  Change in physiological response in premenstrual syndrome group is because of increased sympathetic activity resulting from modulation of neurotransmitter due to hormonal fluctuation.
authors.affiliation: Indira Gandhi Govt Medical College, Nagpur, Maharashtra, INDIA.
authors.forename: M V
authors.initials: MV
authors.lastname: Rode
authors.affiliation: Indira Gandhi Govt Medical College, Nagpur, Maharashtra, INDIA.
authors.forename: P
authors.initials: P
authors.lastname: Kamble
authors.affiliation: Indira Gandhi Govt Medical College, Nagpur, Maharashtra, INDIA.
authors.forename: M S
authors.initials: MS
authors.lastname: Phatak
authors.affiliation: Indira Gandhi Govt Medical College, Nagpur, Maharashtra, INDIA.
authors.forename: P
authors.initials: P
authors.lastname: Jadhao
authors.affiliation: Indira Gandhi Govt Medical College, Nagpur, Maharashtra, INDIA.
authors.forename: P
authors.initials: P
authors.lastname: Tayde
keywords: Blood pressure; Heart rate post; Menstrual phase; Premenstrual phase; Premenstrual syndrome