title: Vascular changes caused by deep brain stimulation using double-dose gadolinium-enhanced brain MRI.
abstract: We retrospectively analyzed the clinical data of 32 patients with medically intractable idiopathic Parkinson's disease who had undergone staged bilateral deep brain stimulation of the subthalamic nuclei from January 2007 to May 2011. The vascularture of the patients who received two deep brain stimulations was detected using double-dose gadolinium-enhanced brain MRI. The dimensions of straight sinus, superior sagittal sinus, ipsilateral internal cerebral vein in the thalamic branch and ipsilateral anterior caudate vein were reduced. These findings demonstrate that bilateral deep brain stimulation of the subthalamic nuclei affects cerebral venous blood flow.
authors.affiliation: Department of Neurological Surgery, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.
authors.forename: Byeong Sam
authors.initials: BS
authors.lastname: Choi
authors.affiliation: Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, IN, USA.
authors.forename: Yong Hwan
authors.initials: YH
authors.lastname: Kim
authors.affiliation: Department of Neurological Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Sang Ryong
authors.initials: SR
authors.lastname: Jeon
keywords: KRCF National Agenda Project; anterior caudate vein; deep brain stimulation; gadolinium-enhanced brain MRI; internal cerebral vein in the thalamic branch; nerve regeneration; neural regeneration; straight sinus; subthalamic nuclei; superior sagittal sinus; vascularture