title: Effectiveness of chamomile tea on glycemic control and serum lipid profile in patients with type 2 diabetes.
abstract: OBJECTIVE
  This study aimed at assessing the effects of chamomile tea consumption on glycemic control and serum lipid profile in patients with type 2 diabetes mellitus (T2DM).
  
  
  METHODS
  This single-blind randomized controlled clinical trial was conducted on 64 individuals with T2DM (males and females) aged between 30 and 60 years. The intervention group (n = 32) consumed chamomile tea (3 g/150 mL hot water) three times per day immediately after meals for 8 weeks. The control group (n = 32) followed a water regimen for the same intervention period. Fasting blood samples, anthropometric measurements, and 3-day, 24-h dietary recalls were collected at the baseline and at the end of the trial. Data were analyzed by independent t test, paired t test, Pearson correlation test, and analysis of covariance.
  
  
  RESULTS
  Chamomile tea significantly decreased concentration of HbA1C (p = 0.03), serum insulin levels (p < 0.001), homeostatic model assessment for insulin resistance (p < 0.001), total cholesterol (p = 0.001), triglyceride (p < 0.001), and low-density lipoprotein cholesterol (p = 0.05) compared with control group. No significant changes were shown in serum high-density lipoprotein cholesterol levels in both groups.
  
  
  CONCLUSIONS
  Chamomile tea has some beneficial effects on glycemic control and serum lipid profile in T2DM patients.
authors.affiliation: Department of Nutrition in Community, Faculty of Nutrition, Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
authors.forename: M
authors.initials: M
authors.lastname: Rafraf
authors.affiliation: Students' Research Committee, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran. maryam.zemestani@yahoo.com.
authors.forename: M
authors.initials: M
authors.lastname: Zemestani
authors.affiliation: Department of Statistics and Epidemiology, Faculty of Health, Tabriz Health Service Management Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
authors.forename: M
authors.initials: M
authors.lastname: Asghari-Jafarabadi
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D020843:Chamomile; D002784:Cholesterol / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000175:diagnosis / Q000178:diet therapy*; D005260:Female; D005500:Follow-Up Studies; D038321:Glycemic Index / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D016037:Single-Blind Method; D013662:Tea; D016896:Treatment Outcome; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D008078:Cholesterol, LDL; D008055:Lipids; D013662:Tea; D014280:Triglycerides; D002784:Cholesterol
keywords: Chamomile; Glycemic control; Serum lipids; Type 2 diabetes mellitus