title: Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity.
abstract: 3-Bromo acetyl coumarins (4a-c) on treatment with methyl and ethyl esters of nicotinic acid, isonicotinic acid (5a-d) gave 3-coumrinoyl pyridinium bromides (7a-l) and with quinoline (6) gave 3-coumarinoyl quinolinium bromides (8a-c). The structures of the final compounds were established by their spectral data. The antimicrobial activitiy of all the newly synthesized test compounds were evaluated and some of them, showed good antibacterial activity.
authors.affiliation: Department of Pharmaceutical Chemistry, Al-Ameen College of Pharmacy, Hosur Road, Bangalore, India.
authors.forename: Brajesh
authors.initials: B
authors.lastname: Porwal
authors.affiliation: Department of Pharmaceutical chemistry, College of Pharmaceutical Sciences, Manipal, India.
authors.forename: B S
authors.initials: BS
authors.lastname: Jayashree
authors.affiliation: College of Clinical Pharmacy, King Faisal University, Al-Hasa, KSA.
authors.forename: Mahesh
authors.initials: M
authors.lastname: Attimarad
keywords: Antimicrobial Activity; Coumarins