title: Piston versus scissors: chemotaxis receptors versus sensor His-kinase receptors in two-component signaling pathways.
abstract: In this issue of Structure, Molnar and colleagues present a pair of important advances: (1) a method to analyze multiple signaling states in on-off switch proteins and (2) evidence for a scissors-type mechanism of on-off switching in a full-length, membrane-bound receptor of the sensor histidine-kinase class.
authors.affiliation: Molecular Biophysics Program and Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309-0596, USA. Electronic address: falke@colorado.edu.
authors.forename: Joseph J
authors.initials: JJ
authors.lastname: Falke
mesh_terms: D001426:Bacterial Proteins / Q000737:chemistry*; D003553:Cystine / Q000737:chemistry*; D000071677:Histidine Kinase; D011494:Protein Kinases / Q000737:chemistry*
chemical_list: D001426:Bacterial Proteins; C079792:PhoQ protein, Bacteria; D003553:Cystine; D011494:Protein Kinases; D000071677:Histidine Kinase