title: Use of intrathecal baclofen in children and adolescents: interdisciplinary consensus table 2013.
abstract: In recent years, intrathecal baclofen (ITB) has attained an important role in the treatment of severe spasticity and dystonia in children. There are principal differences between the use of ITB in children and its use in neurology and oncology in adults. Here, we present a consensus report on best practice for the treatment of severe spastic and dystonic movement disorders with ITB. Using a problem-orientated approach to integrate theories and methods, the consensus was developed by an interdisciplinary group of experienced ITB users and experts in the field of movement disorders involving 14 German centers. On the basis of the data pooled from more than 400 patients, the authors have summarized their experience and supporting evidence in tabular form to provide a concise, but still a comprehensive information base that represents our current understanding regarding ITB treatment options in children and adolescents.
authors.affiliation: Department of Paediatric Neurology and Rehabilitation, Epilepsy Center for Children and Adults, Schön Clinic Vogtareuth, Vogtareuth, Germany.
authors.forename: Steffen
authors.initials: S
authors.lastname: Berweck
authors.affiliation: Department of Paediatric Neurology and Rehabilitation, Epilepsy Center for Children and Adults, Schön Clinic Vogtareuth, Vogtareuth, Germany.
authors.forename: Sonnhild
authors.initials: S
authors.lastname: Lütjen
authors.affiliation: Neuropaediatric Outpatient Center, Children's Hospital Auf Der Bult, Hannover, Germany.
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Voss
authors.affiliation: Neuropaediatric Outpatient Center, Children's Hospital Auf Der Bult, Hannover, Germany.
authors.forename: Uta
authors.initials: U
authors.lastname: Diebold
authors.affiliation: Department of Anaesthesia, Children's Intensive Care and Emergency Medicine, Children's Hospital Auf Der Bult, Hannover, Germany.
authors.forename: Karl-Heinz
authors.initials: KH
authors.lastname: Mücke
authors.affiliation: Neuropaediatric Outpatient Clinic, Kinderzentrum St. Martin, Regensburg, Germany.
authors.forename: Angelika
authors.initials: A
authors.lastname: Aisch
authors.affiliation: Neuropaediatric Outpatient Clinic, Kinderzentrum St. Martin, Regensburg, Germany.
authors.forename: Bernhart
authors.initials: B
authors.lastname: Ostertag
authors.affiliation: Neurosurgery Department, University Hospital Regensburg, Regensburg, Germany.
authors.forename: Monika
authors.initials: M
authors.lastname: Friedrich
authors.affiliation: Neuropaediatric Outpatient Clinic, Sana Hospital, Berlin-Lichtenberg, Germany.
authors.forename: Christiane
authors.initials: C
authors.lastname: Wagner
authors.affiliation: Department of Neurosurgery, Schön Clinic Vogtareuth, Vogtareuth, Germany.
authors.forename: Manfred
authors.initials: M
authors.lastname: Kudernatsch
authors.affiliation: Department of Paediatric Neurology and Rehabilitation, Epilepsy Center for Children and Adults, Schön Clinic Vogtareuth, Vogtareuth, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Granel
authors.affiliation: Department of Paediatric Neurology and Rehabilitation, Epilepsy Center for Children and Adults, Schön Clinic Vogtareuth, Vogtareuth, Germany.
authors.forename: Gerhard
authors.initials: G
authors.lastname: Kluger
authors.affiliation: Department of Children's Surgery, Children's Hospital Auf Der Bult, Hannover, Germany.
authors.forename: Barbara
authors.initials: B
authors.lastname: Ludwikowski
authors.affiliation: Department of Neurosurgery, Munich University, Munich, Germany.
authors.forename: Aurelia
authors.initials: A
authors.lastname: Peraud
authors.affiliation: Children's Hospital, St. Vinzenz Hospital, Zams, Austria.
authors.forename: Markus
authors.initials: M
authors.lastname: Rauchenzauner
authors.affiliation: Department of Paediatric Neurology and Developmental Medicine, Dr. von Hauners Children's Hospital, University of Munich, Munich, Germany.
authors.forename: A Sebastian
authors.initials: AS
authors.lastname: Schroeder
authors.affiliation: Gait Laboratory, Motion Analysis and Therapy, Havixbeck, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Sprinz
authors.affiliation: Department of Paediatric Neurology and Rehabilitation, Epilepsy Center for Children and Adults, Schön Clinic Vogtareuth, Vogtareuth, Germany.
authors.forename: Rieke
authors.initials: R
authors.lastname: Wienand
authors.affiliation: Department of Paediatric Neurology, Kassel Hospital, Kassel, Germany.
authors.forename: Bernd
authors.initials: B
authors.lastname: Wilken
authors.affiliation: Department of Neurosurgery, Kassel Hospital, Kassel, Germany.
authors.forename: Stefanie
authors.initials: S
authors.lastname: Kästner
authors.affiliation: Department of Paediatric Neurology and Rehabilitation, Epilepsy Center for Children and Adults, Schön Clinic Vogtareuth, Vogtareuth, Germany.
authors.forename: Caroline
authors.initials: C
authors.lastname: Zeches
authors.affiliation: KBO Children's Centre, Munich, Germany.
authors.forename: Volker
authors.initials: V
authors.lastname: Mall
mesh_terms: D000293:Adolescent; D001418:Baclofen / Q000627:therapeutic use*; D002648:Child; D020821:Dystonic Disorders / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007278:Injections, Spinal; D008297:Male; D009125:Muscle Relaxants, Central / Q000627:therapeutic use*; D009128:Muscle Spasticity / Q000188:drug therapy*; D012720:Severity of Illness Index
chemical_list: D009125:Muscle Relaxants, Central; D001418:Baclofen