title: Anion complexation and the Hofmeister effect.
abstract: The (1)H NMR spectroscopic analysis of the binding of the ClO4(-) anion to the hydrophobic, concave binding site of a deep-cavity cavitand is presented. The strength of association between the host and the ClO4(-) anion is controlled by both the nature and concentration of co-salts in a manner that follows the Hofmeister series. A model that partitions this trend into the competitive binding of the co-salt anion to the hydrophobic pocket of the host and counterion binding to its external carboxylate groups successfully accounts for the observed changes in ClO4(-) affinity.
authors.affiliation: Department of Chemistry, Tulane University, New Orleans, LA 70118 (USA) http://www.gibbgroup.org.
authors.forename: Ryan S
authors.initials: RS
authors.lastname: Carnegie
authors.forename: Corinne L D
authors.initials: CL
authors.lastname: Gibb
authors.forename: Bruce C
authors.initials: BC
authors.lastname: Gibb
mesh_terms: D000838:Anions; D010472:Perchlorates / Q000737:chemistry*; D066244:Proton Magnetic Resonance Spectroscopy; D012492:Salts / Q000737:chemistry
chemical_list: D000838:Anions; D010472:Perchlorates; D012492:Salts; C576518:Perchloric Acid
keywords: Hofmeister effect; anions; host-guest systems; hydrophobic effect