title: Intrinsic differences between oral and skin keratinocytes.
abstract: Keratinocytes cover both the skin and some oral mucosa, but the morphology of each tissue and the behavior of the keratinocytes from these two sites are different. One significant dissimilarity between the two sites is the response to injury. Oral mucosal wounds heal faster and with less inflammation than equivalent cutaneous wounds. We hypothesized that oral and skin keratinocytes might have intrinsic differences at baseline as well as in the response to injury, and that such differences would be reflected in gene expression profiles.
authors.affiliation: Center for Wound Healing and Tissue Regeneration, College of Dentistry, University of Illinois at Chicago, Chicago, Illinois, United States of America.
authors.forename: Anna
authors.initials: A
authors.lastname: Turabelidze
authors.affiliation: Center for Wound Healing and Tissue Regeneration, College of Dentistry, University of Illinois at Chicago, Chicago, Illinois, United States of America.
authors.forename: Shujuan
authors.initials: S
authors.lastname: Guo
authors.affiliation: Center for Wound Healing and Tissue Regeneration, College of Dentistry, University of Illinois at Chicago, Chicago, Illinois, United States of America.
authors.forename: Allison Yen
authors.initials: AY
authors.lastname: Chung
authors.affiliation: Center for Wound Healing and Tissue Regeneration, College of Dentistry, University of Illinois at Chicago, Chicago, Illinois, United States of America.
authors.forename: Lin
authors.initials: L
authors.lastname: Chen
authors.affiliation: The Richard and Loan Hill Department of Bioengineering, College of Engineering, University of Illinois at Chicago, Chicago, Illinois, United States of America.
authors.forename: Yang
authors.initials: Y
authors.lastname: Dai
authors.affiliation: Oregon Health and Science University, School of Dentistry, Portland, Oregon, United States of America.
authors.forename: Phillip T
authors.initials: PT
authors.lastname: Marucha
authors.affiliation: Center for Wound Healing and Tissue Regeneration, College of Dentistry, University of Illinois at Chicago, Chicago, Illinois, United States of America.
authors.forename: Luisa A
authors.initials: LA
authors.lastname: DiPietro
mesh_terms: D000293:Adolescent; D000328:Adult; D002478:Cells, Cultured; D005260:Female; D006801:Humans; D015603:Keratinocytes / Q000378:metabolism* / Q000473:pathology; D008297:Male; D009061:Mouth Mucosa / Q000293:injuries / Q000378:metabolism* / Q000473:pathology; D009928:Organ Specificity; D012867:Skin / Q000293:injuries / Q000378:metabolism* / Q000473:pathology; D014945:Wound Healing; D014947:Wounds and Injuries / Q000378:metabolism* / Q000473:pathology