title: Expression of synaptosomal-associated protein-25 in the rat brain after subarachnoid hemorrhage.
abstract: Synaptosomal-associated protein-25 is an important factor for synaptic functions and cognition. In this study, subarachnoid hemorrhage models with spatial learning disorder were established through a blood injection into the chiasmatic cistern. Immunohistochemical staining and western blot analysis results showed that synaptosomal-associated protein-25 expression in the temporal lobe, hippocampus, and cerebellum significantly lower at days 1 and 3 following subarachnoid morrhage. Our findings indicate that synaptosomal-associated protein-25 expression was down-regulated in the rat brain after subarachnoid hemorrhage.
authors.affiliation: Department of Neurosurgery, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Chen
authors.affiliation: Department of Neurosurgery, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China ; Department of Neurosurgery, Yixing People's Hospital, Yixing 214200, Jiangsu Province, China.
authors.forename: Tong
authors.initials: T
authors.lastname: Hu
authors.affiliation: Department of Neurosurgery, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Li
authors.affiliation: Department of Neurosurgery, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China.
authors.forename: Jianke
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Neurosurgery, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Jia
authors.affiliation: Department of Neurosurgery, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China.
authors.forename: Zhong
authors.initials: Z
authors.lastname: Wang
keywords: brain injury; cerebellum; cognition; cortex; grants-supported paper; hippocampus; neural regeneration; neuroregeneration; subarachnoid hemorrhage; synaptosomal-associated protein-25