title: Chronic mycobacterial meningitis due to Mycobacterium chelonae: a case report.
abstract: We report a case of chronic meningitis due to Mycobacterium chelonae. This organism is a rapidly growing Mycobacterium (RGM) and can be found worldwide in environmental sources such as soil, dust, and water. M. chelonae is an uncommon cause of meningitis; the majority of infections caused by this organism are localized cutaneous or soft tissue infections, and rarely lung infections. The organism is indistinguishable phenotypically, so we applied PCR based on the rpoB gene sequence followed by restriction fragment length polymorphism (RFLP) for molecular identification. The subsequent sequencing of RFLP products revealed 99.7% similarity with M. chelonae.
authors.affiliation: Infectious Diseases Ward, Razi Teaching Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Health Research Institute, Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Shokrallah
authors.initials: S
authors.lastname: Salmanzadeh
authors.affiliation: Infectious Diseases Ward, Razi Teaching Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Negin
authors.initials: N
authors.lastname: Honarvar
authors.affiliation: Department of Microbiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Electronic address: goodarzi200055@yahoo.com.
authors.forename: Hamed
authors.initials: H
authors.lastname: Goodarzi
authors.affiliation: Health Research Institute, Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Department of Microbiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Azar Dokht
authors.initials: AD
authors.lastname: Khosravi
authors.affiliation: Infectious Diseases Ward, Razi Teaching Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Health Research Institute, Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Roohangiz
authors.initials: R
authors.lastname: Nashibi
authors.affiliation: Department of Microbiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Amir Arsalan
authors.initials: AA
authors.lastname: Serajian
authors.affiliation: Department of Microbiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Hashemzadeh
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008581:Meningitis / Q000134:cerebrospinal fluid / Q000382:microbiology*; D009165:Mycobacterium Infections, Nontuberculous / Q000134:cerebrospinal fluid / Q000382:microbiology*; D016926:Mycobacterium chelonae / Q000302:isolation & purification*; D055815:Young Adult
keywords: Chronic meningitis; Mycobacterium chelonae; Rapidly growing mycobacteria