title: Clear cell sarcoma of the right lumbar region: A case report and review of the literature.
abstract: Clear cell sarcoma of soft tissues is a very rare, malignant soft tissue tumor that usually arises in the extremities, with a predilection for the lower limbs. This report presents a 45-year-old male with a painless mass in the right lumbar region for one year. Magnetic resonance imaging showed a 3.6×3.2×1.5-cm soft tissue mass of the right lumbar region. The tumoral cells had pleomorphic nuclei and large amounts of clear cytoplasm, and a proportion of the cells contained melanin. Immunohistochemical analysis was performed, which identified that the cells were positive for S-100, MITF and HMB-45 tumor markers. The patient underwent a postoperative chemotherapy protocol and had no local recurrences at one year post-surgery.
authors.affiliation: Department of Pathology, The First Hospital of Handan City, Handan, Hebei 056002, P.R. China.
authors.forename: Xue-Li
authors.initials: XL
authors.lastname: Yang
authors.affiliation: Department of Pathology, The First Hospital of Handan City, Handan, Hebei 056002, P.R. China.
authors.forename: San-Jun
authors.initials: SJ
authors.lastname: Lu
authors.affiliation: Department of Pathology, The First Hospital of Handan City, Handan, Hebei 056002, P.R. China.
authors.forename: Jie
authors.initials: J
authors.lastname: Xue
authors.affiliation: Department of Pathology, The First Hospital of Handan City, Handan, Hebei 056002, P.R. China.
authors.forename: Yan-Fen
authors.initials: YF
authors.lastname: Wu
authors.affiliation: Department of Pathology, The First Hospital of Handan City, Handan, Hebei 056002, P.R. China.
authors.forename: Jun-Ling
authors.initials: JL
authors.lastname: Shi
keywords: MITF; S-100; clear cell sarcoma of soft tissues; melanin