title: [Reported drug allergy among children attending day care centers].
abstract: BACKGROUND
  Data about drug allergy prevalence in the general population, particularly in children, are lacking. This study aimed to estimate the prevalence of parent-reported drug allergy, in children attending day care centers in Lisbon and Oporto.
  
  
  METHODS
  In Phase II of the "ENVIRH study - Environment and Health in Children Day Care Centers", a health questionnaire which included questions about drug allergies was administered to children by stratified, random sampling of day care centers.
  
  
  RESULTS
  The final analysis included 1,169 questionnaires, 52.5% from boys. The mean age was 3.5 ± 1.5 years. The prevalence of reported drug allergy was 4.1% (95% CI: 3.0 - 5.2%). The most frequently reported drugs were antibiotics (27 cases) and NSAIDs (in 6 cases). In the multivariate analysis, reported drug allergy was directly associated with age (OR 1.19; 95% CI 1.01 - 1.41) and reported food allergy (OR 3.19; 95% CI 1.41 - 7.19). It was inversely associated with the level of parental education (OR 0.25; 95% CI 0.10 - 0.59).
  
  
  CONCLUSIONS
  Even though the limitations of the study our results are in accordance with those reported by previous authors and suggest that there is a high prevalence of reported drug allergy in the considered age group.
  
  
  CONCLUSIONS
  A correct assessment of these situations is needed in order to avoid unnecessary drug evictions.
authors.affiliation: Centro de Estudos de Doenças Crónicas. Faculdade de Ciências Médicas. Universidade Nova de Lisboa. & Serviço de Imunoalergologia. Hospital de Dona Estefânia. Centro Hospitalar Lisboa Central. & Centro de Investigação. Hospital de Dona Estefânia. Centro Hospitalar Lisboa Central. Lisboa. Portugal.
authors.forename: Pedro
authors.initials: P
authors.lastname: Martins
authors.affiliation: Centro de Estudos de Doenças Crónicas. Faculdade de Ciências Médicas. Universidade Nova de Lisboa. & Serviço de Imunoalergologia. Hospital de Dona Estefânia. Centro Hospitalar Lisboa Central. Lisboa. Portugal.
authors.forename: Joana
authors.initials: J
authors.lastname: Belo
authors.affiliation: Centro de Estudos de Doenças Crónicas. Faculdade de Ciências Médicas. Universidade Nova de Lisboa. & Serviço de Imunoalergologia. Hospital de Dona Estefânia. Centro Hospitalar Lisboa Central. Lisboa. Portugal.
authors.forename: João
authors.initials: J
authors.lastname: Marques
authors.affiliation: Departamento de Bioestatística e Informática. Centro de Estudos Anglísticos. Faculdade de Ciências Médicas. Universidade Nova de Lisboa. & Centro de Investigação. Hospital de Dona Estefânia. Centro Hospitalar Lisboa Central. Lisboa. Portugal.
authors.forename: Ana Luísa
authors.initials: AL
authors.lastname: Papoila
authors.affiliation: Centro de Estudos de Doenças Crónicas. Faculdade de Ciências Médicas. Universidade Nova de Lisboa. Lisboa. Portugal.
authors.forename: Iolanda
authors.initials: I
authors.lastname: Caires
authors.affiliation: Centro de Estudos de Doenças Crónicas. Faculdade de Ciências Médicas. Universidade Nova de Lisboa. Lisboa. Portugal.
authors.forename: José
authors.initials: J
authors.lastname: Araújo-Martins
authors.affiliation: Centro de Estudos de Doenças Crónicas. Faculdade de Ciências Médicas. Universidade Nova de Lisboa. Lisboa. Portugal.
authors.forename: Catarina
authors.initials: C
authors.lastname: Pedro
authors.affiliation: Serviço de Imunoalergologia. Hospital da Luz. Lisboa. Portugal.
authors.forename: José
authors.initials: J
authors.lastname: Rosado-Pinto
authors.affiliation: Centro de Investigação. Hospital de Dona Estefânia. Centro Hospitalar Lisboa Central. Lisboa. Portugal.
authors.forename: Daniel
authors.initials: D
authors.lastname: Virella
authors.affiliation: Centro de Estudos de Doenças Crónicas. Faculdade de Ciências Médicas. Universidade Nova de Lisboa. & Serviço de Imunoalergologia. Hospital de Dona Estefânia. Centro Hospitalar Lisboa Central. Lisboa. Portugal.
authors.forename: Paula
authors.initials: P
authors.lastname: Leiria-Pinto
authors.affiliation: Centro de Estudos de Doenças Crónicas. Faculdade de Ciências Médicas. Universidade Nova de Lisboa. & Serviço de Imunoalergologia. Hospital de Dona Estefânia. Centro Hospitalar Lisboa Central. Lisboa. Portugal.
authors.forename: Nuno
authors.initials: N
authors.lastname: Neuparth
mesh_terms: D002656:Child Day Care Centers; D002675:Child, Preschool; D004342:Drug Hypersensitivity / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence