title: Renal complications of beta-thalassemia major in children.
abstract: The success that has been made in the care of patients with thalassemia has led to the emergence of unrecognized complications including several renal abnormalities. Chronic anemia and iron overload as well as the use of iron chelator are believed to lie behind these abnormalities. Many investigators document the presence of tubular dysfunction and abnormalities in glomerular filtration rate in these patients. In this review we will discuss the updates in the diagnosis, pathogenesis and prevention of renal complications of thalassemia.
authors.affiliation: Pediatric Nephrology Unit, Department of Pediatrics, Mansoura University Mansoura, Egypt.
authors.forename: Ashraf
authors.initials: A
authors.lastname: Bakr
authors.affiliation: Pediatric Hematology Unit, Department of Pediatrics, Mansoura University Mansoura, Egypt.
authors.forename: Youssef
authors.initials: Y
authors.lastname: Al-Tonbary
authors.affiliation: Department of Pediatrics, Ministry of Health Khartoum, Sudan.
authors.forename: Ghada
authors.initials: G
authors.lastname: Osman
authors.affiliation: Pediatric Hematology Unit, Department of Pediatrics, Mansoura University Mansoura, Egypt.
authors.forename: Rasha
authors.initials: R
authors.lastname: El-Ashry
keywords: Children; renal complications; thalassemia