title: Phylogeographic Reconstructions of a Rift Valley Fever Virus Strain Reveals Transboundary Animal Movements from Eastern Continental Africa to the Union of the Comoros.
abstract: Major explosive outbreaks of Rift Valley fever (RVF), an arthropod borne zoonotic disease, occur in humans and animals with significant mortality and economic impact across continental Africa and the Indian Ocean region (Madagascar, the Comoros archipelago). Recently, sporadic human cases have been reported in Mayotte and Grande Comore, two islands belonging to the Comoros archipelago. To identify the hypothetical source of virus introduction in an inter-epidemic or a post-epidemic period, a longitudinal survey of livestock was set up in Comorian ruminant populations, known to be susceptible hosts. The phylogeographic genomic analysis has shown that RVF virus (RVFV) detected in a zebu collected in Anjouan in August 2011 seems to be related to the last known epidemic of RVF which occurred in East Africa and Madagascar (2007-2009). This result highlights the fact that RVFV is maintained within local livestock populations and transboundary animal movements from eastern continental Africa to Indian Ocean islands likely result in RVFV crossover.
authors.affiliation: CIRAD, UMR CMAEE, Sainte Clotilde, La Réunion, France.|INRA, UMR 1309 CMAEE, Montpellier, France.|CRVOI (Centre de Recherche et de Veille sur les maladies émergentes dans l'Océan Indien), CYROI, Sainte Clotilde, La Réunion, France.
authors.forename: M
authors.initials: M
authors.lastname: Maquart
authors.affiliation: CRVOI (Centre de Recherche et de Veille sur les maladies émergentes dans l'Océan Indien), CYROI, Sainte Clotilde, La Réunion, France.|IRD, Sainte Clotilde, La Réunion, France.
authors.forename: H
authors.initials: H
authors.lastname: Pascalis
authors.affiliation: Vice-Présidence en charge de l'Agriculture, l'Elevage, la Pêche, l'Industrie, l'Energie et l'Artisanat, Moroni, Union des Comores.
authors.forename: S
authors.initials: S
authors.lastname: Abdouroihamane
authors.affiliation: CIRAD, UMR CMAEE, Sainte Clotilde, La Réunion, France.|INRA, UMR 1309 CMAEE, Montpellier, France.|CRVOI (Centre de Recherche et de Veille sur les maladies émergentes dans l'Océan Indien), CYROI, Sainte Clotilde, La Réunion, France.
authors.forename: M
authors.initials: M
authors.lastname: Roger
authors.affiliation: Vice-Présidence en charge de l'Agriculture, l'Elevage, la Pêche, l'Industrie, l'Energie et l'Artisanat, Moroni, Union des Comores.
authors.forename: F
authors.initials: F
authors.lastname: Abdourahime
authors.affiliation: CIRAD, UMR CMAEE, Sainte Clotilde, La Réunion, France.|INRA, UMR 1309 CMAEE, Montpellier, France.|CRVOI (Centre de Recherche et de Veille sur les maladies émergentes dans l'Océan Indien), CYROI, Sainte Clotilde, La Réunion, France.
authors.forename: E
authors.initials: E
authors.lastname: Cardinale
authors.affiliation: CIRAD, UMR CMAEE, Sainte Clotilde, La Réunion, France.|INRA, UMR 1309 CMAEE, Montpellier, France.|CRVOI (Centre de Recherche et de Veille sur les maladies émergentes dans l'Océan Indien), CYROI, Sainte Clotilde, La Réunion, France.
authors.forename: C
authors.initials: C
authors.lastname: Cêtre-Sossah
mesh_terms: D000349:Africa / Q000453:epidemiology; D000822:Animal Husbandry; D000818:Animals; D017507:Comoros / Q000453:epidemiology; D004196:Disease Outbreaks / Q000662:veterinary*; D008137:Longitudinal Studies; D058974:Phylogeography; D012295:Rift Valley Fever / Q000453:epidemiology* / Q000635:transmission / Q000821:virology; D012296:Rift Valley fever virus / Q000235:genetics / Q000302:isolation & purification*; D012418:Ruminants
keywords: Rift Valley fever; Union of Comoros; livestock; phylogeny; trade