title: Citrobacter koseri septicaemia in a holstein calf.
abstract: A 4-day-old male Holstein calf with dull mentation, nystagmus and blindness was humanely destroyed and subject to necropsy examination. Gross lesions included severe suppurative meningitis characterized by diffuse cloudy thickening of the meninges, bilateral hypopyon and fibrinosuppurative polyarthritis affecting the hocks. Citrobacter koseri was isolated from the meninges, ocular fluid, synovial fluid, spleen and small intestine. Microscopically, there was neutrophilic and histiocytic meningitis with intralesional bacilli, endophthalmitis, neutrophilic splenitis and multiple renal microabscesses. Failure of passive transfer of colostrum was confirmed. This appears to be the first characterization of septicaemia in a calf caused by C. koseri, with lesions comparable with those described in human neonates.
authors.affiliation: College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA; Pathobiology and Diagnostic Investigation, Diagnostic Center for Population and Animal Health, Michigan State University, Lansing, MI 48910, USA. Electronic address: kominem@dcpah.msu.edu.
authors.forename: M
authors.initials: M
authors.lastname: Komine
authors.affiliation: College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA.
authors.forename: A
authors.initials: A
authors.lastname: Massa
authors.affiliation: Pathobiology and Diagnostic Investigation, Diagnostic Center for Population and Animal Health, Michigan State University, Lansing, MI 48910, USA.
authors.forename: L
authors.initials: L
authors.lastname: Moon
authors.affiliation: College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA; Pathobiology and Diagnostic Investigation, Diagnostic Center for Population and Animal Health, Michigan State University, Lansing, MI 48910, USA.
authors.forename: T
authors.initials: T
authors.lastname: Mullaney
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology / Q000473:pathology*; D041041:Citrobacter koseri; D004756:Enterobacteriaceae Infections / Q000473:pathology / Q000662:veterinary*; D008297:Male; D018805:Sepsis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*
keywords: Citrobacter koseri; calf; meningitis; septicaemia