title: Bio-inspired development of a dual-mode nanoprobe for MRI and Raman imaging.
abstract: New generation dual-mode imaging probes for MRI and Raman imaging techniques are developed, inspired by the hyper intense contrast enhancing capability in T1 -weighted MRI and characteristic Raman signal of natural melanin. MDA-MB-231cells labeled with dual-mode imaging probe are successfully detected in both T1-weighted MRI and Raman imaging.
authors.affiliation: School of Chemistry, Seoul National University, Seoul, 151-747, Korea.
authors.forename: Kuk-Youn
authors.initials: KY
authors.lastname: Ju
authors.forename: Sangyeop
authors.initials: S
authors.lastname: Lee
authors.forename: Jung
authors.initials: J
authors.lastname: Pyo
authors.forename: Jaebum
authors.initials: J
authors.lastname: Choo
authors.forename: Jin-Kyu
authors.initials: JK
authors.lastname: Lee
mesh_terms: D032701:Biomimetics / Q000379:methods*; D045744:Cell Line, Tumor; D006046:Gold; D006801:Humans; D008279:Magnetic Resonance Imaging; D053768:Metal Nanoparticles / Q000648:ultrastructure; D013059:Spectrum Analysis, Raman
chemical_list: D006046:Gold
keywords: MRI and raman imaging; dual-mode nanoprobes; hollow gold spheres; imaging; melanin; multimodal imaging