title: Recent developments in VSD imaging of small neuronal networks.
abstract: Voltage-sensitive dye (VSD) imaging is a powerful technique that can provide, in single experiments, a large-scale view of network activity unobtainable with traditional sharp electrode recording methods. Here we review recent work using VSDs to study small networks and highlight several results from this approach. Topics covered include circuit mapping, network multifunctionality, the network basis of decision making, and the presence of variably participating neurons in networks. Analytical tools being developed and applied to large-scale VSD imaging data sets are discussed, and the future prospects for this exciting field are considered.
authors.affiliation: Department of Cell Biology and Anatomy, School of Graduate and Postdoctoral Studies, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA.
authors.forename: Evan S
authors.initials: ES
authors.lastname: Hill
authors.affiliation: Department of Cell Biology and Anatomy, School of Graduate and Postdoctoral Studies, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA Department of Neuroscience, School of Graduate and Postdoctoral Studies, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA.
authors.forename: Angela M
authors.initials: AM
authors.lastname: Bruno
authors.affiliation: Department of Cell Biology and Anatomy, School of Graduate and Postdoctoral Studies, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA william.frost@rosalindfranklin.edu.
authors.forename: William N
authors.initials: WN
authors.lastname: Frost
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D005247:Feeding Behavior / Q000502:physiology; D008124:Locomotion / Q000502:physiology; D009043:Motor Activity / Q000502:physiology; D009415:Nerve Net / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D056969:Voltage-Sensitive Dye Imaging / Q000379:methods*