title: [Risk factors associated with incisional surgical site infection in colorectal cancer surgery with primary anastomosis].
abstract: OBJECTIVE
  To investigate the incidence of surgical site infection (SSI) and risk factors in colorectal cancer surgery patients.
  
  
  METHODS
  Between October 2003 and October 2013, 1 381 consecutive patients with colorectal cancer managed surgically with primary anastomosis were included in the study. There were 762 male and 619 female patients with mean body mass index (BMI) was (27.7 ± 3.7) kg/m², aged from 20 to 90 years with a median of 67 years. Patients undergoing emergency surgery and requiring stoma creation were excluded. The patients' characteristics, surgical conditions and prognosis were recorded. Univariate and multiple logistic regression analysis were used to identify any variable predictive factors of SSI.
  
  
  RESULTS
  One hundred twenty-six (9.12%) cases developed incisional SSI. The occurrence time for SSI was from 2 to 20 days, mean (6.7 ± 2.9) days. According to multivariable logistic regression analysis, BMI (OR = 1.058, P = 0.030), intraoperative contamination (OR = 10.549, P = 0.000) and open operation as compared with a laparoscopic procedure (OR = 2.111, P = 0.001) were significant independent predictors of incisional SSI. There was a significant decrease in incisional SSI in wound protectors group (OR = 1.646, P = 0.012).
  
  
  CONCLUSIONS
  BMI and intraoperative contamination are independent predictors of incisional SSI, and wound protectors and laparoscopic surgery are associated with a lower incidence of incisional SSI following colorectal cancer surgery.
authors.affiliation: Department of General Surgery, Beijing Chaoyang Hosptial, Capital Medical University, Beijing 100020, China.
authors.forename: Jiagang
authors.initials: J
authors.lastname: Han
authors.affiliation: Department of General Surgery, Beijing Chaoyang Hosptial, Capital Medical University, Beijing 100020, China. Email: wang3zj@sohu.com.
authors.forename: Zhenjun
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of General Surgery, Beijing Chaoyang Hosptial, Capital Medical University, Beijing 100020, China.
authors.forename: Guanghui
authors.initials: G
authors.lastname: Wei
authors.affiliation: Department of General Surgery, Beijing Chaoyang Hosptial, Capital Medical University, Beijing 100020, China.
authors.forename: Bingqiang
authors.initials: B
authors.lastname: Yi
authors.affiliation: Department of General Surgery, Beijing Chaoyang Hosptial, Capital Medical University, Beijing 100020, China.
authors.forename: Huachong
authors.initials: H
authors.lastname: Ma
authors.affiliation: Department of General Surgery, Beijing Chaoyang Hosptial, Capital Medical University, Beijing 100020, China.
authors.forename: Zhigang
authors.initials: Z
authors.lastname: Gao
authors.affiliation: Department of General Surgery, Beijing Chaoyang Hosptial, Capital Medical University, Beijing 100020, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Department of General Surgery, Beijing Chaoyang Hosptial, Capital Medical University, Beijing 100020, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Zhao
authors.affiliation: Department of General Surgery, Beijing Chaoyang Hosptial, Capital Medical University, Beijing 100020, China.
authors.forename: Baocheng
authors.initials: B
authors.lastname: Zhao
authors.affiliation: Department of General Surgery, Beijing Chaoyang Hosptial, Capital Medical University, Beijing 100020, China.
authors.forename: Yunlu
authors.initials: Y
authors.lastname: Tao
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000714:Anastomosis, Surgical; D015992:Body Mass Index; D015179:Colorectal Neoplasms / Q000601:surgery*; D003107:Colorectal Surgery; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000209:etiology*; D055815:Young Adult