title: An outcomes protocol for carpal tunnel release: a comparison of outcomes in patients with and without medical comorbidities.
abstract: OBJECTIVE
  To prospectively report the outcomes of open carpal tunnel release with respect to patient age and medical comorbidities.
  
  
  METHODS
  Nine hundred fifty open carpal tunnel procedures in 826 patients (age range, 21-100 y) at a high-volume orthopedic surgery center were evaluated. Self-reported symptom severity and functional scores were collected using the validated Boston Carpal Tunnel Outcomes questionnaire preoperatively, and at 2 weeks, 6 weeks, and 12 weeks postoperatively.
  
  
  RESULTS
  Patients demonstrated a significant improvement in symptom severity scores at 2 weeks and functional severity scores at 6 weeks. Documented patient medical comorbidities did not affect improvement after surgery. Patients with diabetes improved more slowly but were not significantly different at 6 weeks. Patients with workers' compensation insurance were significantly worse at baseline, 2 weeks, and 6 weeks but were not significantly different at 3 months. The risk of negative postoperative endpoints was slightly higher in patients with a medical comorbidity, though not statistically different.
  
  
  CONCLUSIONS
  Significant improvements in symptom severity and hand function may be expected after open carpal tunnel release in the general population regardless of age, medical comorbidities, or workers' compensation status.
  
  
  METHODS
  Therapeutic III.
authors.affiliation: Department of Orthopaedic Surgery, University of Minnesota, Minneapolis; and TRIA Orthopaedic Center, Bloomington, MN. Electronic address: PaulJCagleMD@gmail.com.
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Cagle
authors.affiliation: Department of Orthopaedic Surgery, University of Minnesota, Minneapolis; and TRIA Orthopaedic Center, Bloomington, MN.
authors.forename: Megan
authors.initials: M
authors.lastname: Reams
authors.affiliation: Department of Orthopaedic Surgery, University of Minnesota, Minneapolis; and TRIA Orthopaedic Center, Bloomington, MN.
authors.forename: Julie
authors.initials: J
authors.lastname: Agel
authors.affiliation: Department of Orthopaedic Surgery, University of Minnesota, Minneapolis; and TRIA Orthopaedic Center, Bloomington, MN.
authors.forename: Deb
authors.initials: D
authors.lastname: Bohn
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002349:Carpal Tunnel Syndrome / Q000150:complications* / Q000503:physiopathology / Q000601:surgery*; D016022:Case-Control Studies; D015331:Cohort Studies; D016208:Databases, Factual; D005260:Female; D006801:Humans; D019458:Insurance Coverage; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D020127:Recovery of Function; D057566:Self Report; D014942:Workers' Compensation; D055815:Young Adult
keywords: Carpal tunnel complication; carpal tunnel outcomes; carpal tunnel release; carpal tunnel syndrome