title: A highly versatile convergent/divergent "onion peel" synthetic strategy toward potent multivalent glycodendrimers.
abstract: Both convergent and divergent strategies for the synthesis of "onion peel" glycodendrimers are reported which resulted in one of the best multivalent ligands known against the virulent factor from a bacterial lectin isolated from Pseudomonas aeruginosa.
authors.affiliation: Pharmaqam, Department of Chemistry, University of Quebec a Montreal, C.P. 8888, Succ. Centre-Ville, Montreal, Quebec, Canada H3C 3P8. roy.rene@uqam.ca.
authors.forename: Rishi
authors.initials: R
authors.lastname: Sharma
authors.forename: Naresh
authors.initials: N
authors.lastname: Kottari
authors.forename: Yoann M
authors.initials: YM
authors.lastname: Chabre
authors.forename: Leïla
authors.initials: L
authors.lastname: Abbassi
authors.forename: Tze Chieh
authors.initials: TC
authors.lastname: Shiao
authors.forename: René
authors.initials: R
authors.lastname: Roy
mesh_terms: D050091:Dendrimers / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D005989:Glycerides / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D037102:Lectins / Q000737:chemistry; D008024:Ligands; D015394:Molecular Structure; D011550:Pseudomonas aeruginosa / Q000737:chemistry; D037521:Virulence Factors / Q000037:antagonists & inhibitors
chemical_list: D050091:Dendrimers; D005989:Glycerides; D037102:Lectins; D008024:Ligands; D037521:Virulence Factors