title: Is Mitral Annular Calcification Associated With Atherosclerotic Risk Factors and Severity and Complexity of Coronary Artery Disease?
abstract: We assessed the association of mitral annular calcification (MAC) with atherosclerotic risk factors and severity and complexity of coronary artery disease (CAD). Cardiac catheterization reports and electronic medical records from 2010 to 2011 were retrospectively reviewed. A total of 481 patients were divided into 2 groups: MAC present (209) and MAC absent (272). All major cardiovascular risk factors, comorbidities, and coronary lesion characteristics were included. On linear regression analysis, age (P = .001, β 1.12) and female gender (P = .031, β 0.50) were the independent predictors of MAC. Mitral annular calcification was not independently associated with the presence of lesions with >70% stenosis (P = .283), number of obstructive vessels (P = .469), lesions with 50% to 70% stenosis (P = .458), and Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery score (P = .479). Mitral annular calcification is probably a benign marker of age-related degenerative changes in the heart independent of the severity and complexity of CAD.
authors.affiliation: Department of Internal Medicine, Lutheran Medical Center, Brooklyn, NY, USA cardiothorax@gmail.com.
authors.forename: Hemal
authors.initials: H
authors.lastname: Bhatt
authors.affiliation: Department of Internal Medicine, Lutheran Medical Center, Brooklyn, NY, USA.
authors.forename: Dharmesh
authors.initials: D
authors.lastname: Sanghani
authors.affiliation: Department of Internal Medicine, Lutheran Medical Center, Brooklyn, NY, USA.
authors.forename: Kell
authors.initials: K
authors.lastname: Julliard
authors.affiliation: Department of Cardiology, Lutheran Medical Center, Brooklyn, NY, USA.
authors.forename: George
authors.initials: G
authors.lastname: Fernaine
mesh_terms: D000368:Aged; D002114:Calcinosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D006328:Cardiac Catheterization; D003324:Coronary Artery Disease / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006349:Heart Valve Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000473:pathology*; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D012737:Sex Factors; D014463:Ultrasonography
keywords: SYNTAX score; cardiovascular risk factors; mitral annular calcification