title: Evaluation of seasonal chemical composition, antibacterial, antioxidant and anticholinesterase activity of essential oil from Eugenia brasiliensis Lam.
abstract: This study describes the seasonal composition and the antibacterial, antioxidant and anticholinesterase activity of the essential oil from Eugenia brasiliensis leaves. Analysis by using GC allowed the identification of 40 compounds. It was observed that the monoterpenes varied more (42%) than the sesquiterpenes (14%), and that the monoterpene hydrocarbons suffered the greatest variation throughout the year (64%). Major compounds were spathulenol in the spring (16.02 ± 0.44%) and summer (18.17 ± 0.41%), τ-cadinol in the autumn (12.83 ± 0.03%) and α-pinene (15.94 ± 0.58%) in the winter. Essential oils were tested for their antibacterial activity, and the best result was obtained from the autumn oil, with MIC = 500 μg mL(- 1) against Staphylococcus saprophyticus and Pseudomonas aeruginosa. Antioxidant activity was evaluated using DPPH, lipid peroxidation and iron-reducing power assays, as well as the anticholinesterase activity. Both tests showed a weak performance of the essential oils.
authors.affiliation: a Departamento de Ciências Farmacêuticas , Universidade Regional de Blumenau , Rua São Paulo, 2171, CEP 89030-000 , Blumenau , SC , Brazil.
authors.forename: Diogo Alexandre
authors.initials: DA
authors.lastname: Siebert
authors.forename: Adrielli
authors.initials: A
authors.lastname: Tenfen
authors.forename: Celina Noriko
authors.initials: CN
authors.lastname: Yamanaka
authors.forename: Caio Maurício Mendes
authors.initials: CM
authors.lastname: de Cordova
authors.forename: Dilamara Riva
authors.initials: DR
authors.lastname: Scharf
authors.forename: Edésio Luiz
authors.initials: EL
authors.lastname: Simionatto
authors.forename: Michele Debiasi
authors.initials: MD
authors.lastname: Alberton
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry*; D000975:Antioxidants / Q000737:chemistry*; D002800:Cholinesterase Inhibitors / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D039821:Monoterpenes / Q000737:chemistry / Q000302:isolation & purification; D009822:Oils, Volatile / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012621:Seasons; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification; D057790:Staphylococcus saprophyticus / Q000187:drug effects; D027842:Syzygium / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D000975:Antioxidants; D002800:Cholinesterase Inhibitors; D039821:Monoterpenes; D009822:Oils, Volatile; D012717:Sesquiterpenes
keywords: Eugenia brasiliensis; antibacterial; anticholinesterase; antioxidant; essential oil