title: Analysis of risk factors for vascular cognitive impairment in patients with cerebral infarction.
abstract: This study aimed to identify risk factors for vascular cognitive impairment (VCI) in cerebral infarction patients. Associations between VCI and age, gender, blood pressure, lipid levels, glycosylated hemoglobin, atrial fibrillation, tobacco smoking, alcohol consumption, homocysteine (Hcy), and High-Sensitivity C-Reactive Protein (HS-CRP) were evaluated in patients with cerebral infarction (n = 300) using single factor analysis and multivariate logistic regression analysis. By single factor analysis, the age, glycosylated hemoglobin, atrial fibrillation, blood pressure, Hcy, HS-CRP, tobacco smoking, and alcohol consumption were significantly associated with VCI in these patients. By multivariate logistic regression analysis, the age, glycosylated hemoglobin, blood pressure, Hcy, and HS-CRP were revealed as independent risk factors. The age, glycosylated hemoglobin, blood pressure, Hcy, and HS-CRP can serve as predictive factors for VCI in patients with cerebral infarction.
authors.affiliation: Department of Neurology, The Central Hospital of Xuzhou, No. 199 Jiefang South Road, Xuzhou, 221009, China, 15852177980@163.com.
authors.forename: Xiao-lei
authors.initials: XL
authors.lastname: An
authors.forename: Chuan-ling
authors.initials: CL
authors.lastname: Li
mesh_terms: D000367:Age Factors; D000368:Aged; D000428:Alcohol Drinking; D001794:Blood Pressure; D002097:C-Reactive Protein / Q000378:metabolism; D002544:Cerebral Infarction / Q000150:complications* / Q000453:epidemiology; D003072:Cognition Disorders / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D012907:Smoking
chemical_list: D006454:Hemoglobins; D002097:C-Reactive Protein