title: Simultaneous quantification of 10 saponins in Chinese Shizhu Panax by UPLC-ESI-MS.
abstract: A simple and rapid method was established and validated for the simultaneous quantification of 10 saponins, namely ginsenosides-Rb1, Rb2, Rb3, Rc, Rd, Rg1, Rg2, Re, Rf and Notoginsenside R1, in Chinese Shizhu Panax by ultra performance liquid chromatography coupled with an electrospray mass spectrometry (UPLC-ESI-MS). In addition, the contents of the analytes in different parts of Chinese Shizhu Panax were also analysed. The results showed that the concentration of saponins had a reference to the different parts of Chinese Shizhu Panax. The established method could be used as a new analytical approach for assessment of the quantity of Chinese Shizhu Panax.
authors.affiliation: a School of Pharmacy, Shenyang Pharmaceutical University , Shenyang 110016 , P.R. China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Jiang
authors.forename: Long-Shan
authors.initials: LS
authors.lastname: Zhao
authors.forename: Zhi-Li
authors.initials: ZL
authors.lastname: Xiong
authors.forename: Xu-Ling
authors.initials: XL
authors.lastname: Peng
authors.forename: Xing-Jie
authors.initials: XJ
authors.lastname: Guo
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004365:Drugs, Chinese Herbal / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification*; D004578:Electron Spin Resonance Spectroscopy; D015394:Molecular Structure; D005894:Panax / Q000737:chemistry*; D012503:Saponins / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D004365:Drugs, Chinese Herbal; D012503:Saponins
keywords: Chinese Shizhu Panax; UPLC-ESI-MS; ginsenosides; quantification