title: Role of Montelukast in treatment of mild and severe forms of asthma.
abstract: The aim of the study was to evaluate the effect of Montelukast - leukotriene inhibitor in longitudinal treatment of mild and severe forms of asthma. The research was conducted at LTD Kutaisi Nazarishvili Regional center of Family Medicine. Retrospect analysis of 187 patients histories were carried out. Patients histories were grouped according to the severity of the disease, method of treatment (monotherapy with inhaled glycocorticoid and inhaled glycocorticoid combined with leucotriene inhibitor) in different age groups. The results of measurements of lung function - especially spirometry (FEV1 - Forced Expiratory Volume1 sec and PEF- Peak Expiratory Flow) were studied. Descriptive statistics methods were used to characterize each variable. Our results indicate on positive role of montelukast - leukotrien inhibitor in the treatment of severe and mild forms of asthma.
authors.affiliation: Tbilisi State Medical University; A. Tsereteli State University, Faculty of Health Care, Kutaisi; 3D. Nazarishvili Regional Center of Family Medicine, Kutaisi, Georgia.
authors.forename: E
authors.initials: E
authors.lastname: Ekaladze
authors.affiliation: Tbilisi State Medical University; A. Tsereteli State University, Faculty of Health Care, Kutaisi; 3D. Nazarishvili Regional Center of Family Medicine, Kutaisi, Georgia.
authors.forename: I
authors.initials: I
authors.lastname: Pkhakadze
authors.affiliation: Tbilisi State Medical University; A. Tsereteli State University, Faculty of Health Care, Kutaisi; 3D. Nazarishvili Regional Center of Family Medicine, Kutaisi, Georgia.
authors.forename: N
authors.initials: N
authors.lastname: Alavidze
authors.affiliation: Tbilisi State Medical University; A. Tsereteli State University, Faculty of Health Care, Kutaisi; 3D. Nazarishvili Regional Center of Family Medicine, Kutaisi, Georgia.
authors.forename: K
authors.initials: K
authors.lastname: Jugeli
mesh_terms: D000085:Acetates / Q000008:administration & dosage / Q000627:therapeutic use*; D000280:Administration, Inhalation; D000293:Adolescent; D000328:Adult; D018927:Anti-Asthmatic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy* / Q000209:etiology*; D003521:Cyclopropanes; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D020024:Leukotriene Antagonists / Q000627:therapeutic use; D008168:Lung / Q000187:drug effects / Q000502:physiology; D008875:Middle Aged; D011804:Quinolines / Q000008:administration & dosage / Q000627:therapeutic use*; D012129:Respiratory Function Tests; D012189:Retrospective Studies; D013147:Spirometry; D013440:Sulfides; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000085:Acetates; D018927:Anti-Asthmatic Agents; D003521:Cyclopropanes; D005938:Glucocorticoids; D020024:Leukotriene Antagonists; D011804:Quinolines; D013440:Sulfides; C093875:montelukast