title: Catalytic hydroamination of unactivated olefins using a Co catalyst for complex molecule synthesis.
abstract: Functional group tolerance is one of the important requirements for chemical reactions, especially for the synthesis of complex molecules. Herein, we report a mild, general, and functional group tolerant intramolecular hydroamination of unactivated olefins using a Co(salen) complex, an N-fluoropyridinium salt, and a disiloxane reagent. This method, which was carried out at room temperature (or 0 °C), afforded three-, five-, six-, and seven-membered ring nitrogen-containing heterocyclic compounds and was compatible with diverse functional groups.
authors.affiliation: Faculty of Pharmacy, Musashino University , 1-1-20 Shinmachi Nishitokyo-shi, Tokyo 202-8585, Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Shigehisa
authors.forename: Natsumi
authors.initials: N
authors.lastname: Koseki
authors.forename: Nao
authors.initials: N
authors.lastname: Shimizu
authors.forename: Mayu
authors.initials: M
authors.lastname: Fujisawa
authors.forename: Makoto
authors.initials: M
authors.lastname: Niitsu
authors.forename: Kou
authors.initials: K
authors.lastname: Hiroya
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000586:Amination; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*
chemical_list: D000475:Alkenes; D000588:Amines; D006571:Heterocyclic Compounds; D009942:Organometallic Compounds; D003035:Cobalt