title: Effect of a natural feed additive (Macleaya cordata), containing sanguinarine, on the performance and health status of weaning pigs.
abstract: The aim of this study was to investigate the efficacy of Sangrovit(®) , a plant-derived feed additive, given throughout the nursery stage via feed at 15 ppm and 50 ppm, on the health status and performance of weaners against negative controls. In a 900-sow farrow-to-finish farm, a total of 864 piglets were divided into three groups: (i) negative controls (NC); (ii) Sang 15: same feed as NCs, plus 15 g Sangrovit(®) /t of feed; (iii) Sang 50: same feed as NCs plus 50 g Sangrovit(®) /t of feed. The results indicated that administration of 50 ppm(-) Sangrovit(®) had the most beneficial effects on growth performance in weaning pigs. Specifically there was increase of body weight and average daily gain, as well as reduction of feed conversion ratio. Blood analysis from the Sang groups and especially the Sang 50 group revealed low values of haptoglobin and serum amyloid A.
authors.affiliation: Department of Animal Production, Technological Educational Institute of Thessaly, Larissa, Greece.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Kantas
authors.forename: Vasileios G
authors.initials: VG
authors.lastname: Papatsiros
authors.forename: Panagiotis D
authors.initials: PD
authors.lastname: Tassis
authors.forename: Labrini V
authors.initials: LV
authors.lastname: Athanasiou
authors.forename: Eleni D
authors.initials: ED
authors.lastname: Tzika
mesh_terms: D000821:Animal Feed; D000818:Animals; D000833:Animals, Suckling / Q000254:growth & development*; D053119:Benzophenanthridines / Q000008:administration & dosage / Q000494:pharmacology*; D001835:Body Weight / Q000187:drug effects*; D019587:Dietary Supplements; D004305:Dose-Response Relationship, Drug; D005503:Food Additives / Q000008:administration & dosage / Q000494:pharmacology*; D006242:Haptoglobins / Q000378:metabolism; D007546:Isoquinolines / Q000008:administration & dosage / Q000494:pharmacology*; D000685:Serum Amyloid A Protein / Q000378:metabolism; D013552:Swine / Q000254:growth & development* / Q000378:metabolism*; D014886:Weaning
chemical_list: D053119:Benzophenanthridines; D005503:Food Additives; D006242:Haptoglobins; D007546:Isoquinolines; D000685:Serum Amyloid A Protein; C005705:sanguinarine
keywords: additive; haptoglobin; pig; sanguinarine; serum amyloid A