title: Inflammation: the dynamic force of health and disease.
abstract: Replacing "happiness" with "inflammation" in Thomas Merton's quotation holds true for the processes that govern our immune response and health. The balance between pro- and anti-inflammatory signals regulates inflammatory responses, leading to either restoration of health or the development and progression of disease, depending on whether it creates equilibrium or dysfunction. This issue of Clinical Pharmacology & Therapeutics highlights emerging research and concepts related to inflammation and its underlying role in chronic disease and variable drug response.
authors.affiliation: Department of Oncology, UCL Cancer Institute, University College London, London, UK.
authors.forename: V
authors.initials: V
authors.lastname: Vassileva
authors.affiliation: Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Piquette-Miller
mesh_terms: D000375:Aging / Q000276:immunology / Q000378:metabolism; D001327:Autoimmune Diseases / Q000188:drug therapy / Q000276:immunology / Q000378:metabolism; D004347:Drug Interactions; D004734:Energy Metabolism; D006706:Homeostasis; D006801:Humans; D007249:Inflammation / Q000188:drug therapy / Q000276:immunology / Q000378:metabolism*; D009369:Neoplasms / Q000188:drug therapy / Q000276:immunology / Q000378:metabolism; D009765:Obesity / Q000276:immunology / Q000378:metabolism / Q000517:prevention & control