title: The impact of serum uric acid on the diagnostic of metabolic syndrome in apparently healthy brazilian middle-aged men.
abstract: Hyperuricemia is related to Metabolic Syndrome (MetS) and cardiovascular diseases, but the use of serum uric acid (UA) to diagnose MetS is currently ignored in clinical practices.
  
  
  
  To examine the impact of serum UA on the diagnostic of MetS and the relationship of serum UA with cardiometabolic risk factors in apparently healthy Brazilian middle-aged men residents in a city of Minas Gerais.
  
  
  
  In a cross-sectional analysis, 289 apparently healthy middle-aged men underwent anthropometric, clinical, sociodemographic and blood serum biochemical evaluation. By using receive operating curve the internal cutoff of serum UA was determined (5.25 mg/dL).
  
  
  
  Subjects with two or more components of MetS exhibited higher serum UA as compared to those with one or none component. The inclusion of serum UA ≥ 5.25mg/dL as an additional component of MetS increased the occurrence of this syndrome by 13%. Subjects with UA ≥ 5.25mg/dL showed high prevalence for MetS and association with its components (central obesity, hypertriglyceridemia, dyslipidemia and hypertension) as well as atherogenic risk.
  
  
  
  Serum UA has an important impact on the diagnostic of MetS and is related to cardiometabolic risk factors in apparently healthy Brazilian middle-aged men. Its use in clinical practices could aggregate accuracy to diagnose MetS.
authors.affiliation: Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil. Department of Physical Education Science and Health, Universidade Federal de São João del-Rei, São João del-Rei, Minas Gerais, Brazil.. alessandro@ufsj.edu.br.
authors.forename: Alessandro
authors.initials: A
authors.lastname: de Oliveira
authors.affiliation: Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.. helenhermana@ufv.br.
authors.forename: Helen Hermana Miranda
authors.initials: HHM
authors.lastname: Hermsdorff
authors.affiliation: Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.. guedescocate@yahoo.com.br.
authors.forename: Paula
authors.initials: P
authors.lastname: Guedes Cocate
authors.affiliation: Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.. jbrm@ufv.br.
authors.forename: Josefina
authors.initials: J
authors.lastname: Bressan
authors.affiliation: Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.. alexnove2005@hotmail.com.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Azevedo Novello
authors.affiliation: Department of General Biology, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.. lisacardoso2000@yahoo.com.br.
authors.forename: Eliziária
authors.initials: E
authors.lastname: Cardoso dos Santos
authors.affiliation: Department of Physical Education, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.. anatali@ufv.br.
authors.forename: Antônio
authors.initials: A
authors.lastname: José Natali
mesh_terms: D001938:Brazil; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000209:etiology; D003430:Cross-Sectional Studies; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood* / Q000150:complications / Q000175:diagnosis*; D008875:Middle Aged; D012307:Risk Factors; D014527:Uric Acid / Q000097:blood*
chemical_list: D014527:Uric Acid