title: A novel lung nodules detection scheme based on vessel segmentation on CT images.
abstract: Lung vessels often interfere with the detection of lung nodules. In this paper, a novel computer-aided lung nodule detection scheme on vessel segmentation is proposed. This paper describes an active contour model which can combine image region mean gray value and image edge energy. It is used to segment and remove lung vessels. A selective shape filter based on Hessian Matrix is used to detect suspicious nodules and remove omitted lung vessels. This paper extracts density, shape and position features of suspicious nodules, and uses a Rule-Based Classification (RBC) method to identify true positive nodules. In the experiment results, the detection sensitivity is about 90% and FP is 1/scan.
authors.affiliation: College of Information Science and Engineering, Northeastern University, Shenyang 110819, China Key Laboratory of Medical Image Computing, Ministry of Education Shenyang 110819, China.
authors.forename: Tong
authors.initials: T
authors.lastname: Jia
authors.affiliation: College of Information Science and Engineering, Northeastern University, Shenyang 110819, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Zhang
authors.affiliation: College of Information Science and Engineering, Northeastern University, Shenyang 110819, China.
authors.forename: Haixiu
authors.initials: H
authors.lastname: Meng
mesh_terms: D000465:Algorithms; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging*; D010363:Pattern Recognition, Automated / Q000379:methods*; D011651:Pulmonary Artery / Q000000981:diagnostic imaging*; D011856:Radiographic Image Enhancement / Q000379:methods; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D003074:Solitary Pulmonary Nodule / Q000000981:diagnostic imaging*; D013382:Subtraction Technique; D014057:Tomography, X-Ray Computed / Q000379:methods*
keywords: CT image; Lung vessel segmentation; active contour model; lung nodule detection