title: Molecular diagnostics in the management of chronic hepatitis C: key considerations in the era of new antiviral therapies.
abstract: Molecular tests that detect and/or quantify HCV RNA are important in the diagnosis and management of patients with chronic hepatitis C (CHC) undergoing anti-viral therapy. The primary goal of anti-HCV therapy is to achieve a sustained virologic response (SVR) defined as "undetectable" Hepatitis C Virus (HCV) RNA in the serum or plasma at 12 to 24 weeks following the end of treatment.
authors.forename: Bryan
authors.initials: B
authors.lastname: Cobb
authors.forename: Gabrielle
authors.initials: G
authors.lastname: Heilek
authors.forename: Regis A
authors.initials: RA
authors.lastname: Vilchez
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000627:therapeutic use*; D016174:Hepacivirus / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D019698:Hepatitis C, Chronic / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology / Q000821:virology*; D006801:Humans; D008875:Middle Aged; D057089:Pathology, Molecular; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents