title: Metallophytes for organic synthesis: towards new bio-based selective protection/deprotection procedures.
abstract: We propose for the first time using metal hyperaccumulating plants for the construction of a repertoire of protection and deprotection conditions in a concept of orthogonal sets. Protection of alcohol, carbonyl, carboxyl, and amino groups are considered. The ecocatalysts derived from metal-rich plants allow selective, mild, eco-friendly, and efficient protection or deprotection reactions. The selectivity is controlled by the choice of the metal, which is hyperaccumulated by the metallophyte.
authors.affiliation: Institut de Chimie Moléculaire et des Matériaux d'Orsay, Université Paris Sud, Rue du Doyen Georges Poitou, 91405, Orsay Cedex, France.
authors.forename: Claire M
authors.initials: CM
authors.lastname: Grison
authors.forename: Alicia
authors.initials: A
authors.lastname: Velati
authors.forename: Vincent
authors.initials: V
authors.lastname: Escande
authors.forename: Claude
authors.initials: C
authors.lastname: Grison
mesh_terms: D000107:Acetylation; D000438:Alcohols / Q000737:chemistry; D019607:Brassicaceae / Q000378:metabolism*; D002245:Carbon Dioxide / Q000737:chemistry; D002384:Catalysis; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D002855:Chromatography, Thin Layer; D008401:Gas Chromatography-Mass Spectrometry; D055772:Green Chemistry Technology / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy; D018515:Plant Leaves / Q000378:metabolism; D010943:Plantago / Q000378:metabolism*; D039105:Proteaceae / Q000378:metabolism*; D015032:Zinc / Q000378:metabolism / Q000493:pharmacokinetics*
chemical_list: D000438:Alcohols; D002245:Carbon Dioxide; C041069:carboxyl radical; D015032:Zinc