title: "Out of pollen" hypothesis for origin of new genes in flowering plants: study from Arabidopsis thaliana.
abstract: New genes, which provide material for evolutionary innovation, have been extensively studied for many years in animals where it is observed that they commonly show an expression bias for the testis. Thus, the testis is a major source for the generation of new genes in animals. The source tissue for new genes in plants is unclear. Here, we find that new genes in plants show a bias in expression to mature pollen, and are also enriched in a gene coexpression module that correlates with mature pollen in Arabidopsis thaliana. Transposable elements are significantly enriched in the new genes, and the high activity of transposable elements in the vegetative nucleus, compared with the germ cells, suggests that new genes are most easily generated in the vegetative nucleus in the mature pollen. We propose an "out of pollen" hypothesis for the origin of new genes in flowering plants.
authors.affiliation: State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China.
authors.forename: Dong-Dong
authors.initials: DD
authors.lastname: Wu
authors.affiliation: Laboratory for Conservation and Utilization of Bio-resources, Yunnan University, Kunming, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.affiliation: State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Zeng
authors.affiliation: State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada Banting and Best Diabetes Centre, University of Toronto, Toronto, Canada.
authors.forename: David M
authors.initials: DM
authors.lastname: Irwin
authors.affiliation: State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China Laboratory for Conservation and Utilization of Bio-resources, Yunnan University, Kunming, China Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China zhangyp@mail.kiz.ac.cn.
authors.forename: Ya-Ping
authors.initials: YP
authors.lastname: Zhang
mesh_terms: D017360:Arabidopsis / Q000235:genetics* / Q000502:physiology; D004251:DNA Transposable Elements / Q000235:genetics*; D018506:Gene Expression Regulation, Plant / Q000235:genetics / Q000502:physiology; D030821:Plants, Genetically Modified / Q000235:genetics / Q000502:physiology*; D011058:Pollen / Q000235:genetics* / Q000502:physiology
chemical_list: D004251:DNA Transposable Elements
keywords: Arabidopsis thaliana; young gene evolution; “Out of pollen” hypothesis