title: Human papillomavirus-related basaloid squamous cell carcinoma of the bladder associated with genital tract human papillomavirus infection.
abstract: Basaloid squamous cell carcinoma is a biologically aggressive neoplasm mainly found in the head and neck region. Recently, four cases of basaloid squamous cell carcinoma of the bladder have been reported, and three of them occurred in patients with neurogenic bladder, repeated catheterizations and human papillomavirus infection of the urinary tract. To the best of our knowledge, none of the patients affected by basaloid squamous cell carcinoma of the bladder described in the literature had documented genital involvement by human papillomavirus. Herein, we describe the case of a woman with neurogenic bladder affected by basaloid squamous cell carcinoma of the bladder and by a concomitant genital tract human papillomavirus infection.
authors.affiliation: Department of Medical Biotechnologies, Pathology Unit, University of Siena, Siena, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Ginori
authors.forename: Aurora
authors.initials: A
authors.lastname: Barone
authors.forename: Rosa
authors.initials: R
authors.lastname: Santopietro
authors.forename: Gabriele
authors.initials: G
authors.lastname: Barbanti
authors.forename: Filippo
authors.initials: F
authors.lastname: Cecconi
authors.forename: Sergio Antonio
authors.initials: SA
authors.lastname: Tripodi
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000628:therapy / Q000821:virology; D003131:Combined Modality Therapy; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D027383:Papillomaviridae / Q000235:genetics* / Q000302:isolation & purification; D030361:Papillomavirus Infections / Q000175:diagnosis* / Q000628:therapy / Q000821:virology; D060737:Reproductive Tract Infections / Q000175:diagnosis* / Q000628:therapy / Q000821:virology; D001743:Urinary Bladder / Q000473:pathology / Q000821:virology*; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000628:therapy / Q000821:virology
chemical_list: D004279:DNA, Viral
keywords: basaloid squamous cell carcinoma; bladder; epithelial-mesenchymal transition; human papillomavirus; p16