title: Vancomycin-induced acute tubular necrosis.
abstract: OBJECTIVE
  To report nephrotoxicity in the form of acute tubular necrosis (ATN) related to vancomycin.
  
  
  METHODS
  This study was conducted at Johns Hopkins Aramco Healthcare, Saudi Aramco, Dharan, Saudi Arabia between June and August 2013. All patients who received intravenous vancomycin as a part of the hospital's vancomycin stewardship program were monitored for the development of ATN.
  
  
  RESULTS
  A total of 89 patients received vancomycin over a 3-month period. Three patients developed ATN attributed to high levels of vancomycin, with an incidence of 3.4%.
  
  
  CONCLUSIONS
  Intravenous vancomycin is nephrotoxic and can lead to ATN. The medical community must be aware of the potential risks of vancomycin associated nephrotoxicity. Renal function and vanomycin drug levels should be closely monitored.
authors.affiliation: Johns Hopkins Aramco Healthcare, Saudi Aramco, PO Box 10955, Dhahran 31311, Kingdom of Saudi Arabia. Tel. +966 (13) 8779748. Fax. +966 (13) 8773790. E-mail. aalkhunaizi@gmail.com.
authors.forename: Ahmed M
authors.initials: AM
authors.lastname: Alkhunaizi
authors.forename: Kareem
authors.initials: K
authors.lastname: Hinedi
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007683:Kidney Tubular Necrosis, Acute / Q000139:chemically induced*; D014640:Vancomycin / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin