title: A direct C-H/Ar-H coupling approach to oxindoles, thio-oxindoles, 3,4-dihydro-1 H-quinolin-2-ones, and 1,2,3,4-tetrahydroquinolines.
abstract: A copper(II)-catalysed approach to oxindoles, thio-oxindoles, 3,4-dihydro-1H-quinolin-2-ones, and 1,2,3,4-tetrahydroquinolines via formal C-H, Ar-H coupling is described. In a new variant, copper(II) 2-ethylhexanoate has been identified as an inexpensive and efficient catalyst for this transformation, which utilises atmospheric oxygen as the re-oxidant.
authors.affiliation: Department of Chemistry, University of York, Heslington, York, YO10 5DD (UK), Fax: (+44) 1904324523.
authors.forename: Timothy E
authors.initials: TE
authors.lastname: Hurst
authors.forename: Ryan M
authors.initials: RM
authors.lastname: Gorman
authors.forename: Pauline
authors.initials: P
authors.lastname: Drouhin
authors.forename: Alexis
authors.initials: A
authors.lastname: Perry
authors.forename: Richard J K
authors.initials: RJ
authors.lastname: Taylor
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D016877:Oxidants / Q000737:chemistry; D000078183:Oxindoles; D011804:Quinolines / Q000737:chemistry*; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D007211:Indoles; D016877:Oxidants; D000078183:Oxindoles; D011804:Quinolines; D013438:Sulfhydryl Compounds; C022960:2-oxindole; D003300:Copper; C542964:1,2,3,4-tetrahydroquinoline
keywords: catalysis; copper; dihydroquinolinones; oxindoles; tetrahydroquinolines