title: The effort-reward imbalance work-stress model and daytime salivary cortisol and dehydroepiandrosterone (DHEA) among Japanese women.
abstract: We examined the influence of work-related effort-reward imbalance and overcommitment to work (OC), as derived from Siegrist's Effort-Reward Imbalance (ERI) model, on the hypothalamic-pituitary-adrenocortical (HPA) axis. We hypothesized that, among healthy workers, both cortisol and dehydroepiandrosterone (DHEA) secretion would be increased by effort-reward imbalance and OC and, as a result, cortisol-to-DHEA ratio (C/D ratio) would not differ by effort-reward imbalance or OC. The subjects were 115 healthy female nursery school teachers. Salivary cortisol, DHEA, and C/D ratio were used as indexes of HPA activity. Mixed-model analyses of variance revealed that neither the interaction between the ERI model indicators (i.e., effort, reward, effort-to-reward ratio, and OC) and the series of measurement times (9:00, 12:00, and 15:00) nor the main effect of the ERI model indicators was significant for daytime salivary cortisol, DHEA, or C/D ratio. Multiple linear regression analyses indicated that none of the ERI model indicators was significantly associated with area under the curve of daytime salivary cortisol, DHEA, or C/D ratio. We found that effort, reward, effort-reward imbalance, and OC had little influence on daytime variation patterns, levels, or amounts of salivary HPA-axis-related hormones. Thus, our hypotheses were not supported.
authors.affiliation: Department of Public Health, Fujita Health University School of Medicine, Toyoake, Japan.
authors.forename: Atsuhiko
authors.initials: A
authors.lastname: Ota
authors.affiliation: Department of Public Health, Fujita Health University School of Medicine, Toyoake, Japan.
authors.forename: Junji
authors.initials: J
authors.lastname: Mase
authors.affiliation: Department of Epidemiology, Faculty of Public Health, Mahidol University, Bangkok, Thailand.
authors.forename: Nopporn
authors.initials: N
authors.lastname: Howteerakul
authors.affiliation: Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.
authors.forename: Thitipat
authors.initials: T
authors.lastname: Rajatanun
authors.affiliation: Department of Public Health Administration, Faculty of Public Health, Mahidol University, Bangkok, Thailand.
authors.forename: Nawarat
authors.initials: N
authors.lastname: Suwannapong
authors.affiliation: Department of Public Health, Fujita Health University School of Medicine, Toyoake, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yatsuya
authors.affiliation: Department of Public Health, Fujita Health University School of Medicine, Toyoake, Japan.
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Ono
mesh_terms: D000328:Adult; D002940:Circadian Rhythm / Q000502:physiology*; D003430:Cross-Sectional Studies; D003687:Dehydroepiandrosterone / Q000032:analysis* / Q000378:metabolism; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis* / Q000378:metabolism; D007564:Japan; D008875:Middle Aged; D012201:Reward; D012463:Saliva / Q000737:chemistry*; D013315:Stress, Psychological / Q000503:physiopathology* / Q000523:psychology*; D013663:Teaching; D055815:Young Adult
chemical_list: D003687:Dehydroepiandrosterone; D006854:Hydrocortisone