title: Effects of routine rehabilitation training on glucose tolerance among nondiabetic stroke patients: a pilot study.
abstract: OBJECTIVE
  Impaired glucose tolerance (IGT) and diabetic glucose tolerance (DGT) are closely associated with vascular disease mortality and morbidity. This study was designed to determine whether routine stroke rehabilitation training can be used to improve the glucose status and whether IGT and DGT persist among nondiabetic stroke patients at discharge after such training.
  
  
  METHODS
  Eighty eligible subjects were evaluated using Oral Glucose Tolerance Tests (OGTTs) at entry and discharge at the rehabilitation medical departments of two large hospitals in China. Routine rehabilitation training was provided during hospitalization. The secondary outcome measurements were BMI, Fugl-Meyer motor score, Barthel index, HbA1c, triglycerides, HDL cholesterol and LDL cholesterol. Non-acute and nondiabetic stroke patients treated at the rehabilitation department.
  
  
  RESULTS
  Fifty-four patients had IGT or DGT at entry, while 61 patients exhibited abnormal glucose tolerance at discharge, accounting for 67.7% and 76.25% of all subjects respectively. The mean 2-hour plasma glucose level was 8.98 mmol/L at entry and 9.11 mmol/L at discharge. No changes were noted in the OGTT results or secondary outcomes after training (p>0.05), with the exceptions of significant improvements in the Fugl-Meyer motor score and Barthel index (p<0.05).
  
  
  CONCLUSIONS
  These preliminary results suggest that IGT and DGT are present at a high frequency among nondiabetic stroke patients both before and after routine rehabilitation training. Routine stroke rehabilitation training, which greatly improves functional outcomes, may have no effect on the incidence of abnormal glucose tolerance.
authors.affiliation: Rehabilitation Department, The Second Medical School of Nanjing University of Traditional Chinese Medicine, China.
authors.forename: Zun
authors.initials: Z
authors.lastname: Wang
authors.forename: Hongjuan
authors.initials: H
authors.lastname: Fan
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
authors.forename: Tong
authors.initials: T
authors.lastname: Wang
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D005260:Female; D005500:Follow-Up Studies; D018149:Glucose Intolerance / Q000097:blood* / Q000150:complications; D005951:Glucose Tolerance Test; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D020521:Stroke / Q000097:blood / Q000150:complications; D000071939:Stroke Rehabilitation
chemical_list: D001786:Blood Glucose