title: Standardization and quality assurance of radiation therapy volumes for adults with high-grade gliomas.
abstract: Standard treatment for Glioblastoma Multiforme (GBM) consists of a combination of chemotherapy and radiation therapy followed by adjuvant chemotherapy. While the optimal dose of radiation therapy has been established, significant variability in volume of tissue irradiated exists. In this article we review the current guidelines, patterns of care, patterns of failure, imaging advances and toxicity related to radiation therapy volumes in the treatment of GBM.
authors.affiliation: Department of Radiation Oncology, University of California, San Francisco, (UCSF), School of Medicine, San Francisco, CA. Electronic address: FoghSE@RadOnc.ucsf.edu.
authors.forename: Shannon
authors.initials: S
authors.lastname: Fogh
authors.affiliation: Department of Radiation Oncology, University of California, San Francisco, (UCSF), School of Medicine, San Francisco, CA.
authors.forename: Michael
authors.initials: M
authors.lastname: Wahl
authors.affiliation: Department of Radiation Oncology, University of California, San Francisco, (UCSF), School of Medicine, San Francisco, CA.
authors.forename: Mekhail
authors.initials: M
authors.lastname: Anwar
authors.affiliation: Department of Radiation Oncology, University of California, San Francisco, (UCSF), School of Medicine, San Francisco, CA.
authors.forename: Daphne
authors.initials: D
authors.lastname: Haas-Kogan
authors.affiliation: Departments of Neurology and Neurological Surgery, University of California, San Francisco, (UCSF), School of Medicine, San Francisco, CA.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Clarke
authors.affiliation: Department of Radiation Oncology, University of California, San Francisco, (UCSF), School of Medicine, San Francisco, CA.
authors.forename: Penny K
authors.initials: PK
authors.lastname: Sneed
mesh_terms: D005909:Glioblastoma / Q000532:radiotherapy*; D005910:Glioma / Q000532:radiotherapy*; D006801:Humans; D011785:Quality Assurance, Health Care / Q000379:methods*; D011879:Radiotherapy Dosage