title: An evaluation of treatment integrity in a randomised controlled trial of memory rehabilitation for people with multiple sclerosis.
abstract: OBJECTIVE
  To assess the treatment integrity of a memory rehabilitation programme for people with multiple sclerosis.
  
  
  METHODS
  Data were drawn from the intervention group of a randomised controlled trial of memory rehabilitation. This comprised 24 participants with multiple sclerosis.
  
  
  METHODS
  Four core session components were identified from the treatment manual: recap, activities, take-home activity and other. One video-recording of each of ten intervention sessions was transcribed and amount of time spent on components recorded.
  
  
  RESULTS
  There were no significant differences between early and late stages of the programme in time spent on the core components (recap Z= -0.87, P=0.49; activities Z = -0.29, P=0.89; take-home activity Z = -0.59, P=0.69; other Z = -0.58, P=0.69). Thus, adherence to the manual was good with no evidence of programme drift.
  
  
  CONCLUSIONS
  Good adherence indicates the intervention was delivered as described in the manual and strengthens confidence in the findings of the randomised controlled trial.
authors.affiliation: Division of Rehabilitation and Ageing, University of Nottingham, UK lwxkjsm@nottingham.ac.uk.
authors.forename: Kathryn J
authors.initials: KJ
authors.lastname: Smale
authors.affiliation: Central Surrey Health, Surrey, UK.
authors.forename: Sara E
authors.initials: SE
authors.lastname: Carr
authors.affiliation: Central Surrey Health, Surrey, UK.
authors.forename: Annette F
authors.initials: AF
authors.lastname: Schwartz
authors.affiliation: Division of Rehabilitation and Ageing, University of Nottingham, UK.
authors.forename: Roshan
authors.initials: R
authors.lastname: das Nair
authors.affiliation: Division of Rehabilitation and Ageing, University of Nottingham, UK.
authors.forename: Nadina B
authors.initials: NB
authors.lastname: Lincoln
mesh_terms: D000328:Adult; D000368:Aged; D001291:Attitude of Health Personnel; D005260:Female; D019983:Guideline Adherence; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000209:etiology / Q000534:rehabilitation*; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications / Q000534:rehabilitation*; D017063:Outcome Assessment, Health Care; D017410:Practice Guidelines as Topic
keywords: Memory rehabilitation; multiple sclerosis; process evaluation; treatment integrity