title: Associations between dairy intake and metabolic risk parameters in a healthy French-Canadian population.
abstract: Observational studies support that dairy product intake is associated with a reduced risk of developing type 2 diabetes; however, several clinical studies report conflicting results on the association between dairy product consumption and metabolic parameters. The aim of this study was to determine associations between dairy product consumption and metabolic profile. Dietary data, using a validated food frequency questionnaire, and fasting blood samples were collected from 233 French Canadians. Plasma phospholipid (PL) fatty acids (FA) concentrations were determined by gas chromatography. Subjects consumed 2.5 ± 1.4 portions of dairy products daily, including 1.6 ± 1.3 portions of low-fat (LF) and 0.90 ± 0.70 portions of high-fat (HF) dairy products. Trans-palmitoleic acid level in plasma PL was related to HF dairy consumption (r = 0.15; p = 0.04). Total (r = -0.21; p = 0.001) and LF dairy (r = -0.20; p = 0.003) intakes were inversely correlated with fasting plasma glucose level. Total dairy intake was inversely associated to systolic blood pressure (r = -0.17; p = 0.008) and diastolic blood pressure (r = -0.14; p = 0.03). LF dairy intake was also inversely correlated with systolic blood pressure (r = -0.17; p = 0.009). Total dairy intake was correlated with plasma C-reactive protein (CRP) (r = 0.15; p = 0.03). No association was found between HF dairy consumption and the risk factors studied. In conclusion, dairy intake is inversely associated with glycaemia and blood pressure; yet, it may modify CRP levels. Moreover, trans-palmitoleic FA levels in plasma PL may be potentially used to assess full-fat dairy consumption.
authors.affiliation: a Endocrinology and Nephrology, CHU de Québec Research Center, 2705 boul. Laurier, QC G1V 4G2, Canada.
authors.forename: Marine S
authors.initials: MS
authors.lastname: Da Silva
authors.forename: Pierre
authors.initials: P
authors.lastname: Julien
authors.forename: Patrick
authors.initials: P
authors.lastname: Couture
authors.forename: Simone
authors.initials: S
authors.lastname: Lemieux
authors.forename: Marie-Claude
authors.initials: MC
authors.lastname: Vohl
authors.forename: Iwona
authors.initials: I
authors.lastname: Rudkowska
mesh_terms: D000328:Adult; D002170:Canada; D003611:Dairy Products; D004435:Eating; D005227:Fatty Acids / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008659:Metabolic Diseases / Q000097:blood / Q000453:epidemiology*; D010743:Phospholipids / Q000097:blood; D012307:Risk Factors
chemical_list: D005227:Fatty Acids; D010743:Phospholipids
keywords: acides gras trans; blood glucose; blood pressure; dairy products; différences sexuelles; glucose sanguin; phospholipides plasmatiques; plasma phospholipids; produits laitiers; sex differences; tension artérielle; trans-fatty acids