title: Catalytic α-monoallylation of aryl acetonitriles.
abstract: α-Cyano aldehydes undergo selective transition-metal-catalyzed monoallylation to provide α-allylated nitriles. The transformation leads to linear substitution products with palladium catalysts or branched allylated nitriles using an iridium catalyst. Facile TBD-catalyzed retro-Claisen cleavage is leveraged to attain selective monoallylation.
authors.affiliation: Department of Chemistry, The University of Kansas , 2010 Malott Hall, 1251 Wescoe Hall Drive, Lawrence, Kansas 66045, United States.
authors.forename: Tapan
authors.initials: T
authors.lastname: Maji
authors.forename: Jon A
authors.initials: JA
authors.lastname: Tunge