title: The use of Collatamp G, local gentamicin-collagen sponge, in reducing wound infection.
abstract: We conducted a retrospective study to examine the role of Collatamp G in reducing postoperative surgical site infection (SSI) in patients with different wound classes. Ninety-two patients (62 men and 30 women; mean age, 58 years; range, 29-88 years) who had undergone surgery between December 2009 and November 2011 in Tan Tock Seng Hospital and who had application of Collatamp G in their wound before closure were included in the study. The primary endpoint was the development of any superficial wound infection within 1 month postoperatively. Of 92 patients studied, 9 (10%) developed a superficial wound infection. Two of 43 patients with clean-contaminated wounds (5%), 2 of 19 with contaminated wounds (11%), and 5 of 30 with dirty-infected wounds (16%) developed infection. Use of the larger size Collatamp G (10 × 10 cm) also appears to have a lower incidence of SSI compared with the smaller Collatamp G (5 × 5 cm); 4% and 12%, respectively. Our data suggest that postoperative SSI was reduced in the group of patients with dirty-infected wound class. SSI appears to be decreased with use of the larger size Collatamp G.
authors.affiliation: Department of Surgery, Tan Tock Seng Hospital, Singapore.
authors.forename: Clement L K
authors.initials: CL
authors.lastname: Chia
authors.forename: Vishal G
authors.initials: VG
authors.lastname: Shelat
authors.forename: Wilson
authors.initials: W
authors.lastname: Low
authors.forename: Sheena
authors.initials: S
authors.lastname: George
authors.forename: Jaideepraj
authors.initials: J
authors.lastname: Rao
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D003094:Collagen; D016503:Drug Delivery Systems; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013530:Surgical Wound Infection / Q000517:prevention & control*
chemical_list: D005839:Gentamicins; D003094:Collagen
keywords: Collatamp G; Dirty infected; Gentamicin-collagen; Surgical site infection; Wound class