title: First report of Westerdykella dispersa as a cause of an angioinvasive fungal infection in a neutropenic host.
abstract: Angioinvasive fungal infections (AFIs) are an important cause of morbidity and mortality among immunocompromised patients. However, clinicomicrobiological characteristics and treatment of many AFI agents remain poorly defined. We report the first human case of infection with Westerdykella dispersa, an emergent cause of AFI, which was successfully treated in a neutropenic pediatric patient.
authors.affiliation: Division of Pediatric Infectious Diseases, Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
authors.forename: Paul K
authors.initials: PK
authors.lastname: Sue
authors.affiliation: Division of Microbiology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
authors.forename: Grzegorz T
authors.initials: GT
authors.lastname: Gurda
authors.affiliation: Microbiology Laboratory, The Johns Hopkins Hospital, Baltimore, Maryland, USA.
authors.forename: Richard
authors.initials: R
authors.lastname: Lee
authors.affiliation: Division of Microbiology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
authors.forename: Tonya
authors.initials: T
authors.lastname: Watkins
authors.affiliation: Microbiology Laboratory, The Johns Hopkins Hospital, Baltimore, Maryland, USA.
authors.forename: Rachel
authors.initials: R
authors.lastname: Green
authors.affiliation: Microbiology Laboratory, The Johns Hopkins Hospital, Baltimore, Maryland, USA.
authors.forename: Warda
authors.initials: W
authors.lastname: Memon
authors.affiliation: Division of Pediatric Infectious Diseases, Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
authors.forename: Aaron M
authors.initials: AM
authors.lastname: Milstone
authors.affiliation: Microbiology Service, Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: Adrian M
authors.initials: AM
authors.lastname: Zelazny
authors.affiliation: Microbiology Service, Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: Gary A
authors.initials: GA
authors.lastname: Fahle
authors.affiliation: Molecular Diagnostics Unit, Laboratory of Pathology, National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: Thu Anh
authors.initials: TA
authors.lastname: Pham
authors.affiliation: University of Alberta Microfungus Collection and Herbarium, Edmonton, AB, Canada.
authors.forename: Connie F
authors.initials: CF
authors.lastname: Gibas
authors.affiliation: Fungus Testing Laboratory, University of Texas Health Science Center, San Antonio, Texas, USA.
authors.forename: Deanna A
authors.initials: DA
authors.lastname: Sutton
authors.affiliation: Fungus Testing Laboratory, University of Texas Health Science Center, San Antonio, Texas, USA.
authors.forename: Brian L
authors.initials: BL
authors.lastname: Wickes
authors.affiliation: Fungus Testing Laboratory, University of Texas Health Science Center, San Antonio, Texas, USA.
authors.forename: Nathan P
authors.initials: NP
authors.lastname: Wiederhold
authors.affiliation: Division of Microbiology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA Microbiology Laboratory, The Johns Hopkins Hospital, Baltimore, Maryland, USA szhang28@jhmi.edu.
authors.forename: Sean X
authors.initials: SX
authors.lastname: Zhang
mesh_terms: D001203:Ascomycota / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D002648:Child; D004271:DNA, Fungal / Q000737:chemistry / Q000235:genetics; D021903:DNA, Ribosomal Spacer / Q000737:chemistry / Q000235:genetics; D006651:Histocytochemistry; D006801:Humans; D016867:Immunocompromised Host; D007267:Injections / Q000009:adverse effects; D008297:Male; D008828:Microbiological Techniques; D008853:Microscopy; D008969:Molecular Sequence Data; D009181:Mycoses / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology*; D009503:Neutropenia / Q000150:complications*; D013902:Radiography, Thoracic; D017422:Sequence Analysis, DNA; D014057:Tomography, X-Ray Computed; D014657:Vasculitis / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology*
chemical_list: D004271:DNA, Fungal; D021903:DNA, Ribosomal Spacer