title: Room temperature alkynylation of H-phosphi(na)tes and secondary phosphine oxides with ethynylbenziodoxolone (EBX) reagents.
abstract: Highly efficient protocols for the alkynylation of H-phosphi(na)tes and secondary phosphine oxides with silyl, aryl and alkyl ethynyl-benziodoxolone (EBX) reagents are reported. Alkynyl phosphorus compounds were obtained in 69-93% yield without the need for a transition metal catalyst at room temperature under open flask conditions.
authors.affiliation: Laboratory of Catalysis and Organic Synthesis, Ecole Polytechnique Fédérale de Lausanne, EPFL SB ISIC LCSO, BCH 4306, 1015 Lausanne (CH), Switzerland. jerome.waser@epfl.ch.
authors.forename: C Chun
authors.initials: CC
authors.lastname: Chen
authors.forename: Jerome
authors.initials: J
authors.lastname: Waser
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D007202:Indicators and Reagents; D007462:Iodobenzenes; D007463:Iodobenzoates / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*; D010721:Phosphinic Acids / Q000737:chemistry*; D013696:Temperature; D028561:Transition Elements / Q000737:chemistry
chemical_list: D000480:Alkynes; D007202:Indicators and Reagents; D007462:Iodobenzenes; D007463:Iodobenzoates; D010087:Oxides; D010720:Phosphines; D010721:Phosphinic Acids; D028561:Transition Elements; C476101:o-iodoxybenzoic acid; C044646:phosphine