title: Rhodium-catalyzed alkylation of C-H bonds in aromatic amides with α,β-unsaturated esters.
abstract: The alkylation of C-H bonds with α,β-unsaturated carbonyl compounds by a rhodium-catalyzed reaction of aromatic amides containing an 8-aminoquinoline moiety is reported. The reaction is highly regioselective. The formation of C-C bonds occurs between the ortho C-H bonds in aromatic amides and the β-position of the acyclic α,β-unsaturated carbonyl compounds. The reaction is applicable to various acyclic α,β-unsaturated carbonyl compounds, such as acrylic esters, acrylamide, fumarate, maleate, and phenyl vinyl sulfone.
authors.affiliation: Department of Applied Chemistry, Faculty of Engineering, Osaka University , Suita, Osaka 565-0871, Japan.
authors.forename: Kaname
authors.initials: K
authors.lastname: Shibata
authors.forename: Naoto
authors.initials: N
authors.lastname: Chatani