title: [The varicocele: the proper therapy for the proper patient].
abstract: Varicocele is present in 15% to 20% of the general population, but in approximately 35% to 40% of males presenting for an evaluation of their infertility. Indeed it is well known that varicocele can cause testicular damage and infertility. No evidence indicates a varicocele treatment in infertile men who have normal semen analysis or in men with subclinical varicocele. In this situation, varicocelectomy cannot be recommended. Varicocele repair may be effective in men with subnormal semen analysis, a clinical varicocele and otherwise unexplained infertility, but we need further randomized studies to confirm that this subgroup of infertile couples will benefit from treatment. There is no doubt about the standard indications of varicocelectomy, but recent literature seems to go towards new indications of varicocele repair. The aim of this review is to give a look at the literature to analyze the proper indications to varicocelectomy for the proper patient.
authors.affiliation: Dipartimento di Neuroscienze, Scienze Riproduttive e Odontostomatologiche, Università "Federico II" di Napoli, Napoli - Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Capece
authors.forename: Ciro
authors.initials: C
authors.lastname: Imbimbo
mesh_terms: D053713:Azoospermia / Q000209:etiology; D003362:Cost-Benefit Analysis; D006801:Humans; D007006:Hypogonadism / Q000209:etiology; D007248:Infertility, Male / Q000209:etiology / Q000517:prevention & control; D010535:Laparoscopy / Q000191:economics / Q000379:methods; D007813:Laparotomy / Q000191:economics / Q000379:methods; D007985:Leydig Cells / Q000378:metabolism / Q000473:pathology; D008297:Male; D015201:Meta-Analysis as Topic; D008866:Microsurgery / Q000379:methods; D018579:Patient Selection; D017410:Practice Guidelines as Topic; D057285:Precision Medicine; D016896:Treatment Outcome; D014646:Varicocele / Q000150:complications / Q000191:economics / Q000532:radiotherapy / Q000601:surgery*