title: Optic neuropathy secondary to eosinophilic angiocentric fibrosis.
abstract: Eosinophilic angiocentric fibrosis (EAF) is a rare fibroinflammatory disorder with a predilection for upper respiratory tract submucosa. We report a 45-year-old man with progressive unilateral visual loss secondary to a retroorbital soft tissue mass with histological features consistent with EAF. The patient experienced marked improvement in vision after endoscopic optic nerve decompression through sphenoethmoidectomy.
authors.affiliation: Department of Otolaryngology (APL, SKA), University Hospitals Birmingham NHS Trust, Queen Elizabeth Hospital, Birmingham, United Kingdom; Birmingham Neuro-Ophthalmology Unit (JDB, TDM), Department of Ophthalmology, University Hospitals Birmingham NHS Trust, Queen Elizabeth Hospital, Birmingham, United Kingdom; Department of Pathology (AW), University Hospitals Birmingham NHS Trust, Queen Elizabeth Hospital, Birmingham, United Kingdom; Department of Ophthalmology (BTSP), University Hospitals Coventry and Warwickshire NHS Trust, Coventry, United Kingdom.
authors.forename: Adam P
authors.initials: AP
authors.lastname: Lloyd
authors.forename: James D
authors.initials: JD
authors.lastname: Benzimra
authors.forename: Adrian T
authors.initials: AT
authors.lastname: Warfield
authors.forename: Balaji T S
authors.initials: BT
authors.lastname: Prasad
authors.forename: Timothy D
authors.initials: TD
authors.lastname: Matthews
authors.forename: Shahzada K
authors.initials: SK
authors.lastname: Ahmed
mesh_terms: D019299:Decompression, Surgical; D018450:Disease Progression; D005355:Fibrosis; D015769:Granuloma, Respiratory Tract / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000503:physiopathology*; D015898:Tomography Scanners, X-Ray Computed