title: An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma.
abstract: OBJECTIVE
  To investigate the pathology and pathogenesis of and treatment methods for temporal bone verrucous carcinoma.
  
  
  METHODS
  A single-patient report of verrucous carcinoma on the left external auditory canal is presented and analyzed along with all cases of temporal bone verrucous carcinoma that have been documented in the English literature.
  
  
  RESULTS
  Most of the patients with verrucous carcinoma of the temporal bone have histories of surgery, trauma, or infection, and verrucous carcinomas are sensitive to antimicrotubule chemotherapeutic medicines. Adjuvant radiation therapy is not effective, but surgical treatment might be relatively more effective.
  
  
  CONCLUSIONS
  Temporal bone verrucous carcinoma has a poor prognosis; therefore, the preferred treatment is surgical resection facilitated with antimicrotubule chemotherapeutic treatment. Adjuvant radiation therapy is not a preferred treatment for temporal bone verrucous carcinoma.
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, People's Republic of China.
authors.forename: Haolei
authors.initials: H
authors.lastname: Tan
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, People's Republic of China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, People's Republic of China.
authors.forename: Gangcai
authors.initials: G
authors.lastname: Zhu
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, People's Republic of China.
authors.forename: Leiming
authors.initials: L
authors.lastname: Pi
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, People's Republic of China.
authors.forename: Donghai
authors.initials: D
authors.lastname: Huang
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, People's Republic of China.
authors.forename: Xin
authors.initials: X
authors.lastname: Zhang
keywords: drug therapy; genetic testing; temporal bone; verrucous carcinoma