title: Adult myelination: wrapping up neuronal plasticity.
abstract: In this review, we outline the major neural plasticity mechanisms that have been identified in the adult central nervous system (CNS), and offer a perspective on how they regulate CNS function. In particular we examine how myelin plasticity can operate alongside neurogenesis and synaptic plasticity to influence information processing and transfer in the mature CNS.
authors.affiliation: Menzies Research Institute Tasmania, University of Tasmania, Hobart 7000, Australia.
authors.forename: Megan
authors.initials: M
authors.lastname: O'Rourke
authors.affiliation: Menzies Research Institute Tasmania, University of Tasmania, Hobart 7000, Australia ; The School of Medicine, University of Tasmania, Hobart 7000, Australia.
authors.forename: Robert
authors.initials: R
authors.lastname: Gasperini
authors.affiliation: Menzies Research Institute Tasmania, University of Tasmania, Hobart 7000, Australia.
authors.forename: Kaylene M
authors.initials: KM
authors.lastname: Young
keywords: NG2; OPC; adult; central nervous system; myelination; neural stem cells; oligodendrocyte; oligodendrogenesis; plasticity; remodelling; synapse