title: Structure and function analysis of protein HD73_0859 produced by Bacillus thuringiensis.
abstract: HD73_0859 is a secretory protein from Bacillus thuringiensis (Bt). In this study, its structural feature was analyzed and its function was predicted. The results revealed that HD73_0859 is a peptidase consists of a signal peptide, three well-separated SH3_3 domains and one Peptidase_M23 domain. The peptidase belongs to the M23/37-metallopeptidase family, and might have enzymatic activity to cell wall peptidoglycan and some elastins. This paper improves the understanding of both the protein HD73_0859 and the M23/37-metallopeptidases family, and lays a foundation for further experimental testing and theoretical study.
authors.affiliation: School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
authors.forename: Dandan
authors.initials: D
authors.lastname: Wang
authors.affiliation: School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
authors.forename: Nan
authors.initials: N
authors.lastname: Zhang
authors.affiliation: School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
authors.forename: Shuyuan
authors.initials: S
authors.lastname: Guo
mesh_terms: D000595:Amino Acid Sequence; D001413:Bacillus thuringiensis / Q000201:enzymology*; D004789:Enzyme Activation; D045726:Metalloproteases / Q000737:chemistry* / Q000648:ultrastructure*; D008969:Molecular Sequence Data; D011487:Protein Conformation
chemical_list: D045726:Metalloproteases
keywords: Bacillus thuringiensis; HD73_0859; analysis; function; structure