title: Proof-of-principle direct double cyclisation of a linear C15-precursor to a dibrominated bicyclic medium-ring ether relevant to Laurencia species.
abstract: Bicyclic dibrominated C15 medium-ring ether hexahydrolaureoxanyne was produced directly from an acyclic model C15-epoxide when treated with NBS with water as the solvent.
authors.affiliation: Department of Chemistry, Imperial College London, London, SW7 2AZ, UK. c.braddock@imperial.ac.uk.
authors.forename: D Christopher
authors.initials: DC
authors.lastname: Braddock
authors.forename: Dan-Tiberiu
authors.initials: DT
authors.lastname: Sbircea
mesh_terms: D001643:Bridged Bicyclo Compounds / Q000737:chemistry*; D001966:Bromine / Q000737:chemistry; D003500:Cyclization; D004852:Epoxy Compounds / Q000737:chemistry; D004987:Ethers / Q000737:chemistry*; D044722:Laurencia / Q000737:chemistry* / Q000378:metabolism; D013237:Stereoisomerism
chemical_list: D001643:Bridged Bicyclo Compounds; D004852:Epoxy Compounds; D004987:Ethers; D001966:Bromine