title: Pediatric migraine prescription patterns at a large academic hospital.
abstract: BACKGROUND
  Here we report the prescription patterns by drug type, age, and sex of patients at a large academic pediatric hospital. Because there are few guidelines based on outcome studies in pediatric migraine, physician treatment approaches in children vary.
  
  
  METHODS
  Using the i2b2 query tool, we determined that over an approximately 4 year period, 4839 patients between the ages of 2 and 17 years were observed at Boston Children's Hospital for migraine with or without aura, 59% women and 41% men.
  
  
  RESULTS
  The most common medications prescribed to this population were sumatriptan, amitriptyline, topiramate, ondansetron, and cyproheptadine.
  
  
  CONCLUSIONS
  Our findings support recent data regarding choices of medication in the pediatric population and additionally support current studies and future investigation into controlled trials in the pediatric population.
authors.affiliation: P.A.I.N. Group, Department of Anesthesia, Boston Children's Hospital, Harvard Medical School, Waltham, Massachusetts; Headache Program, Departments of Anesthesia and Neurology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address: adriana.johnson@childrens.harvard.edu.
authors.forename: Adriana
authors.initials: A
authors.lastname: Johnson
authors.affiliation: Department of Information Services, Boston Children's Hospital, Boston, Massachusetts; Division of Emergency Medicine, Department of Medicine, Boston Children's Hospital, Boston, Massachusetts.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Bickel
authors.affiliation: P.A.I.N. Group, Department of Anesthesia, Boston Children's Hospital, Harvard Medical School, Waltham, Massachusetts; Headache Program, Departments of Anesthesia and Neurology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
authors.forename: Alyssa
authors.initials: A
authors.lastname: Lebel
mesh_terms: D000046:Academic Medical Centers / Q000706:statistics & numerical data*; D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008881:Migraine Disorders / Q000175:diagnosis / Q000188:drug therapy*; D055553:Prescription Drugs / Q000627:therapeutic use*; D012737:Sex Factors
chemical_list: D055553:Prescription Drugs
keywords: amitriptyline; migraine; pediatric; pharmacotherapy; prescription; sumatriptan