title: Reductive umpolung reactions with low-valent titanium catalysts.
abstract: The coupling of similarly polarized carbon fragments can be achieved by a reductive umpolung strategy. This gives access to compounds with functional groups in even bond distances, which are difficult to synthesize by other means. Low-valent titanium catalysts enable such couplings under mild conditions. This account covers the recent progress on this topic with a focus on the development of cross-selective coupling reactions and stereoselective examples.
authors.affiliation: Institut für Organische Chemie, Albert-Ludwigs-Universität Freiburg, D-79104, Freiburg, Germany. jan.streuff@ocbc.uni-freiburg.de.
authors.forename: Jan
authors.initials: J
authors.lastname: Streuff
keywords: homogeneous catalysis; radical reactions; reduction; titanium; umpolung