title: Phytochemistry and pharmacology of the genus pedicularis used in traditional Chinese medicine.
abstract: In the present review, the literature data on the chemical constituents and biological investigations of the genus Pedicularis are summarized. Some species of Pedicularis have been widely applied in traditional Chinese medicine. A wide range of chemical components including iridoid glycosides, phenylpropanoid glycosides (PhGs), lignans glycosides, flavonoids, alkaloids and other compounds have been isolated and identified from the genus Pedicularis. In vitro and in vivo studies indicated some monomer compounds and extracts from the genus Pedicularis have been found to possess antitumor, hepatoprotective, anti-oxidative, antihaemolysis, antibacterial activity, fatigue relief of skeletal muscle, nootropic effect and other activities.
authors.affiliation: Department of Pharmacy, Lanzhou General Hospital of PLA, Lanzhou 730050, P. R. China , School of Pharmacy, Lanzhou University, Lanzhou 730000, P. R. China.
authors.forename: Mao-Xing
authors.initials: MX
authors.lastname: Li
authors.forename: Xi-Rui
authors.initials: XR
authors.lastname: He
authors.forename: Rui
authors.initials: R
authors.lastname: Tao
authors.forename: Xinyuan
authors.initials: X
authors.lastname: Cao
mesh_terms: D000470:Alkaloids / Q000302:isolation & purification; D000818:Animals; D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D000975:Antioxidants; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy; D005221:Fatigue / Q000188:drug therapy; D005419:Flavonoids / Q000302:isolation & purification; D006027:Glycosides / Q000302:isolation & purification; D006801:Humans; D066298:In Vitro Techniques; D057889:Iridoid Glycosides / Q000302:isolation & purification; D017705:Lignans / Q000302:isolation & purification; D008516:Medicine, Chinese Traditional; D051379:Mice; D008968:Molecular Conformation; D018697:Nootropic Agents; D032262:Pedicularis / Q000737:chemistry*; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology* / Q000627:therapeutic use*; D020005:Propanols / Q000302:isolation & purification
chemical_list: D000470:Alkaloids; D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D000975:Antioxidants; D005419:Flavonoids; D006027:Glycosides; D057889:Iridoid Glycosides; D017705:Lignans; D018697:Nootropic Agents; D010936:Plant Extracts; D020005:Propanols; C439395:1-phenylpropanol
keywords: Anti-oxidative Activity; Antitumor Activity; Iridoid Glycosides; Pedicularis; Pharmacology; Phenylpropanoid Glycosides; Phytochemistry; Review