title: Placental Schistosoma haematobium infection in a German returnee from Malawi.
abstract: Schistosomiasis is a widespread helminthic infection which sometimes may affect travelers to endemic areas. We report on a case of urogenital and placental schistosomiasis in a 28-year-old German woman who had been exposed to schistosomiasis in Lake Malawi one year earlier. She experienced painless macrohaematuria in her 21st week of pregnancy. Cystoscopy revealed vesical lesions typical for urogenital schistosomiasis. Histopathology confirmed ova of Schistosoma (S.) haematobium. The patient was treated with praziquantel 40 mg/kg/body weight/day for 3 days. After 285 days of gestation and 18 weeks post treatment, the patient delivered a healthy girl. Histopathology of placenta revealed eggs of S. haematobium in placental stroma. The infant proved negative for anti-Schistosoma spp. antibodies at the age of 15 months. This is the first report on placental schistosomiasis since 1980 and the first case occurring in a traveler.
authors.affiliation: Center for Infectious Diseases and Infection Control, Jena University Hospital, Erlanger Allee 101, 07740, Jena, Thuringia, FR Germany, benjamin.schleenvoigt@med.uni-jena.de.
authors.forename: B T
authors.initials: BT
authors.lastname: Schleenvoigt
authors.forename: M
authors.initials: M
authors.lastname: Gajda
authors.forename: M
authors.initials: M
authors.lastname: Baier
authors.forename: T
authors.initials: T
authors.lastname: Groten
authors.forename: H
authors.initials: H
authors.lastname: Oppel-Heuchel
authors.forename: M O
authors.initials: MO
authors.lastname: Grimm
authors.forename: W
authors.initials: W
authors.lastname: Pfister
authors.forename: J
authors.initials: J
authors.lastname: Richter
authors.forename: M W
authors.initials: MW
authors.lastname: Pletz
mesh_terms: D000328:Adult; D000818:Animals; D005260:Female; D005858:Germany; D006801:Humans; D008295:Malawi; D010922:Placenta Diseases / Q000469:parasitology*; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000469:parasitology*; D012548:Schistosoma haematobium / Q000302:isolation & purification*; D012553:Schistosomiasis haematobia / Q000175:diagnosis*; D014195:Travel