title: Thyroid dysfunction in Indian children with Down syndrome.
abstract: This record review of 82 children with Down Syndrome (DS) between April 2004 and March 2014 who had thyroid dysfunction, showed that majority (76, 92.6%) had subclinical hypothyroidism. Of the 60 patients who underwent radionuclide scan, 63.3% had a normal gland; the rest exhibited only impaired tracer uptake. Ultrasonograms done in 20 patients showed reduction of thyroid gland size in 3 (15%) patients only.
authors.affiliation: Departments of Pediatrics, #Nuclear Medicine and $Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. drdevidayal@gmail.com.
authors.forename: Devi
authors.initials: D
authors.lastname: Dayal
authors.forename: Puneet
authors.initials: P
authors.lastname: Jain
authors.forename: Inusha
authors.initials: I
authors.lastname: Panigrahi
authors.forename: Anish
authors.initials: A
authors.lastname: Bhattacharya
authors.forename: Naresh
authors.initials: N
authors.lastname: Sachdeva
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000150:complications / Q000453:epidemiology; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000150:complications / Q000453:epidemiology; D007194:India / Q000453:epidemiology; D007223:Infant; D008297:Male; D050033:Thyroid Dysgenesis / Q000150:complications / Q000453:epidemiology