title: Neutrophilic sebaceous adenitis with intralobular Demodex mites: a case report and review of the literature.
abstract: A 61-year-old white man presented with a 1-week history of an asymptomatic erythematous, annular plaque with minimal scale limited to the nasal bridge. Histological examination showed a mixed infiltrate of lymphocytes and neutrophils within sebaceous glands. The clinical and histopathological presentation was consistent with a diagnosis of neutrophilic sebaceous adenitis. Several Demodex brevis mites were present deep within the affected sebaceous lobules. Demodex brevis mites are uncommon inhabitants of sebaceous glands of the nose, presenting more commonly on other body sites. The cause of neutrophilic sebaceous adenitis is unknown, but the presence of D. brevis in affected sebaceous glands in this case suggests a possible association.
authors.forename: Maryam
authors.initials: M
authors.lastname: Liaqat
authors.forename: Lindsay H
authors.initials: LH
authors.lastname: Wilson
authors.forename: David
authors.initials: D
authors.lastname: Wada
authors.forename: Scott R
authors.initials: SR
authors.lastname: Florell
authors.forename: Anneli R
authors.initials: AR
authors.lastname: Bowen
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001706:Biopsy; D005148:Facial Dermatoses / Q000175:diagnosis / Q000276:immunology / Q000469:parasitology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008924:Mite Infestations / Q000175:diagnosis / Q000276:immunology / Q000469:parasitology*; D008925:Mites / Q000145:classification / Q000276:immunology / Q000472:pathogenicity*; D009504:Neutrophils / Q000276:immunology / Q000469:parasitology*; D012625:Sebaceous Gland Diseases / Q000175:diagnosis / Q000276:immunology / Q000469:parasitology*; D012627:Sebaceous Glands / Q000276:immunology / Q000469:parasitology*; D016896:Treatment Outcome
chemical_list: D000890:Anti-Infective Agents