title: Substrate specificity and rational design of peptidomimetic inhibitors for SARS coronavirus main protease.
authors.affiliation: School of Life Sciences, The Chinese University of Hong Kong.
authors.forename: K B
authors.initials: KB
authors.lastname: Wong
authors.affiliation: School of Biomedical Sciences, The Chinese University of Hong Kong.
authors.forename: D C C
authors.initials: DC
authors.lastname: Wan
authors.affiliation: Department of Chemistry, The Chinese University of Hong Kong.
authors.forename: H F
authors.initials: HF
authors.lastname: Chow
mesh_terms: D000596:Amino Acids; D000086782:Coronavirus 3C Proteases; D003546:Cysteine Endopeptidases; D015195:Drug Design; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D009842:Oligopeptides / Q000138:chemical synthesis; D057786:Peptidomimetics / Q000138:chemical synthesis; D011480:Protease Inhibitors / Q000138:chemical synthesis; D045473:Severe acute respiratory syndrome-related coronavirus / Q000201:enzymology*; D013379:Substrate Specificity; D014764:Viral Proteins / Q000037:antagonists & inhibitors*
chemical_list: D000596:Amino Acids; C000598688:Cbz-AVLQ-CN; D009842:Oligopeptides; D057786:Peptidomimetics; D011480:Protease Inhibitors; D014764:Viral Proteins; C000706207:3C-like protease, SARS coronavirus; D003546:Cysteine Endopeptidases; D000086782:Coronavirus 3C Proteases