title: Functional nanomaterials can optimize the efficacy of vaccines.
abstract: Nanoscale materials can improve the efficacy of vaccines. Herein we review latest developments that use nanomaterials for vaccines. By highlighting the relationships between the nanoscale physicochemical characteristics and working mechanisms of nanomaterials, this paper shows the current status of the developments where researchers employ functional nanomaterials as vector and/or immunoregulators for vaccines. It also provides us some clues for improving the design and application of nanomaterials to optimize the efficacy of vaccines.
authors.affiliation: Beijing Engineering Research Center for, BioNanotechnology and CAS Key Lab for, Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing, 100190, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Liu
authors.forename: Yingying
authors.initials: Y
authors.lastname: Xu
authors.forename: Yue
authors.initials: Y
authors.lastname: Tian
authors.forename: Chunying
authors.initials: C
authors.lastname: Chen
authors.forename: Chen
authors.initials: C
authors.lastname: Wang
authors.forename: Xingyu
authors.initials: X
authors.lastname: Jiang
mesh_terms: D006801:Humans; D049329:Nanostructures; D014612:Vaccines / Q000008:administration & dosage
chemical_list: D014612:Vaccines
keywords: carriers; immune responses; immunoregulators; nanomaterials; vaccines