title: Corticosteroid use in small animal neurology.
abstract: Glucocorticoid drugs are frequently used nonspecifically by veterinarians to control clinical signs associated with central nervous system disease. However, this use is infrequently justified and can also be associated with detrimental long-term patient outcomes. First, there are few diseases for which glucocorticoids are the preferred or definitive treatment. Second, their actions may blunt subsequent diagnostic efforts, for instance, by altering MRI appearance or cerebrospinal fluid cell content, or lead owners to abandon pursuit of more appropriate therapies if they perceive the first-line steroid therapy to be a failure.
authors.affiliation: Department of Veterinary Clinical Science, College of Veterinary Medicine, Iowa State University, 1600 South 16th Street, Ames, IA 50011, USA. Electronic address: njeffery@iastate.edu.
authors.forename: Nicholas D
authors.initials: ND
authors.lastname: Jeffery
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D002493:Central Nervous System Diseases / Q000188:drug therapy / Q000662:veterinary*; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents
keywords: Dog; Glucocorticoid; Immunosuppression; Inflammation; Intracranial pressure; Meningoencephalomyelitis; Tumor