title: Extended sleeve lobectomy after induction chemoradiotherapy for non-small cell lung cancer.
abstract: OBJECTIVE
  Extended sleeve lobectomy is a challenging surgery. While induction chemoradiotherapy (ChRT) followed by surgery is one of the therapeutic strategies used for locally advanced non-small cell lung cancer (NSCLC), ChRT can impair the anastomotic healing potential. We herein present our experience with cases who underwent an extended sleeve lobectomy after induction ChRT.
  
  
  METHODS
  The medical records of patients who underwent a surgery for NSCLC after ChRT were reviewed.
  
  
  RESULTS
  Between December 2007 and January 2013, nine patients underwent an extended sleeve lobectomy; the left lingular division and lower lobe in four patients, the right upper lobe and trachea in one patient, the carina and trachea in one patient, the right middle and lower lobes in one patient, the right upper and middle lobes and carina in one patient and the right upper lobe and superior segment of the lower lobe in one patient. While no postoperative 90-day deaths occurred, one case developed a bronchopleural fistula on postoperative day (POD) 25 and one case developed a bronchovascular fistula on POD 163. No cases of local recurrence developed.
  
  
  CONCLUSIONS
  Our experience suggests that an extended sleeve lobectomy after induction ChRT is feasible, but careful patient selection and perioperative management are mandatory.
authors.affiliation: Department of Thoracic Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikata-cho, Kita-Ku, Okayama, 700-8558, Japan, toyooka@md.okayama-u.ac.jp.
authors.forename: Shinichi
authors.initials: S
authors.lastname: Toyooka
authors.forename: Junichi
authors.initials: J
authors.lastname: Soh
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Yamamoto
authors.forename: Masaomi
authors.initials: M
authors.lastname: Yamane
authors.forename: Shigeru
authors.initials: S
authors.lastname: Hattori
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Shien
authors.forename: Kentaroh
authors.initials: K
authors.lastname: Miyoshi
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Sugimoto
authors.forename: Takahiro
authors.initials: T
authors.lastname: Oto
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Miyoshi
mesh_terms: D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D060828:Induction Chemotherapy; D008175:Lung Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D019990:Perioperative Care; D011013:Pneumonectomy / Q000379:methods*; D016896:Treatment Outcome