title: [Solitary fibrous hemangiopericytoma of atypical location: importance of immunohistochemical study].
abstract: BACKGROUND
  The rare cutaneous solitary fibrous tumor was initially described in the thoracic cavity in relation to the pleura and subsequently been associated with other serous membranes. It has been described in other extraserosal locations including the skin. Knowledge of its existence along with fairly typical histological features and the immunohistochemical expression pattern with intense positivity for CD34 allow the increasing diagnosis of this condition, which suggests that these cases were not previously diagnosed as such.
  
  
  METHODS
  We report the case of a 43 year-old male with a painless nodule in the first left finger pad clinically suggestive of pyogenic granuloma or nodular melanoma, which was diagnosed by excisional biopsy and immunohistochemical study as a solitary fibrous tumor.
  
  
  CONCLUSIONS
  Only 11 cases of cutaneous solitary fibrous tumor have been published in the following locations: head, cheek, thigh, chest, back and nose. Our work describes the first case of cutaneous solitary fibrous tumor in the hand. The solitary fibrous tumor derived from mesenchymal cells expresses CD34 and hence its presentation in any location. In our case it was in the hand. It explains the problems encountered in the clinical differential diagnosis with other tumors as nodular melanoma, pyogenic granuloma, giant cell tumor of tendon sheath, fibroma, benign peripheral nerve sheath tumors, etc. As we consider the histology, differential diagnosis should be made with other tumors that also express CD34.
  
  
  CONCLUSIONS
  Solitary fibrous tumors derived from mesenchymal cells express CD34 and hence its presentation in any location. In our case it was in the finger pad.
authors.affiliation: Departamento de Dermatología. Hospital Clínico San Cecilio, Granada, Spain.
authors.forename: María Isabel
authors.initials: MI
authors.lastname: Soriano-Hernández
authors.affiliation: Departamento de Dermatología. Hospital Clínico San Cecilio, Granada, Spain. huseinelahmed@hotmail.com.
authors.forename: Husein
authors.initials: H
authors.lastname: Husein-ElAhmed
authors.affiliation: Servicio de Patología, Hospital Infanta Margarita Córdoba, Spain.
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Ruíz-Molina
mesh_terms: D000328:Adult; D018952:Antigens, CD34 / Q000032:analysis*; D000951:Antigens, Neoplasm / Q000032:analysis*; D047310:Apigenin / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis*; D001706:Biopsy; D002148:Calmodulin-Binding Proteins / Q000032:analysis; D003937:Diagnosis, Differential; D005960:Glucosides / Q000032:analysis; D017789:Granuloma, Pyogenic / Q000175:diagnosis; D006393:Hemangiopericytoma / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis; D008648:Mesoderm / Q000737:chemistry; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000032:analysis; D054364:Solitary Fibrous Tumors / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D013933:Thumb / Q000473:pathology* / Q000601:surgery
chemical_list: D018952:Antigens, CD34; D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D002148:Calmodulin-Binding Proteins; D005960:Glucosides; D019253:Proto-Oncogene Proteins c-bcl-2; C117329:vicenin; D047310:Apigenin
keywords: CD34; Cutaneous solitary fibrous tumor; fibrous tissue neoplasms; neoplasias de tejido fibroso; tumor fibroso solitario cutáneo