title: Rubella immunity in women of childbearing age, eight years after the immunization program in iran.
abstract: BACKGROUND
  Rubella is a viral disease with a worldwide distribution. Mass vaccination campaigns have increased the vaccine coverage in the world with substantial impact on reduction of rubella infections. In Iran, the national measles-rubella campaign, targeting individuals 5-25 years old, was initiated in 2003 and mass childhood vaccination against measles, rubella and mumps has continued ever since.
  
  
  OBJECTIVE
  The aim of this study was to evaluate the efficacy of routine vaccination on rubella immunity among women of childbearing age in Babol, north of Iran.
  
  
  METHODS
  This cross-sectional study was conducted on 812 women of childbearing age living in Babol, north of Iran, in 2011. Twelve samples were excluded from the study because of inadequate sera amounts. Serum samples were examined for presence of rubella-specific IgG antibodies by means of quantitative ELISA.
  
  
  RESULTS
  From a total of 800 samples in this study, rubella IgG seropositivity was seen in 786 (98.3% [95% CI = %97.5-%99.1]) cases. The maximum IgG seropositivity (99.2%) was seen in the age group of 21-25 years old and the lowest immunity (87.7%) was in the group of above 30 years old.
  
  
  CONCLUSIONS
  Our data indicated that the rate of seropositivity to rubella virus in our population was high, suggesting that vaccination has been successful in Babol, reducing the likelihood of congenital rubella infection.
authors.affiliation: Infectious Diseases Research Center, Amirkola Children Hospital, Babol University of Medical Sciences, Babol, IR Iran.
authors.forename: Rahim
authors.initials: R
authors.lastname: Barari Sawadkohi
authors.affiliation: Student Research Committee, School of Medicine, Babol University of Medical Sciences, Babol, IR Iran.
authors.forename: Amin
authors.initials: A
authors.lastname: Zarghami
authors.affiliation: Student Research Committee, School of Medicine, Babol University of Medical Sciences, Babol, IR Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Izadpana
authors.affiliation: Non-Communicable Pediatric Diseases Research Center, Amirkola Children Hospital, Babol University of Medical Sciences, Babol, IR Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Pournasrollah
keywords: Congenital Rubella Syndrome; Immunity; Rubella; Vaccination