title: Different impulsivity profiles in borderline personality disorder and bipolar II disorder.
abstract: BACKGROUND
  Borderline personality disorder (BPD) and bipolar II disorder (BP II) share clinical characteristics including impulsivity. Their relationship is disputed. In this study, we investigated self-reported impulsivity in these patient groups and in a healthy control group. Effects of current mood state and of traumatic childhood experiences were explored.
  
  
  METHODS
  Twenty-five patients with BPD without comorbid bipolar disorder; 20 patients with BP II without comorbid BPD; and 44 healthy control subjects completed the UPPS questionnaire which yields assessments of four components of impulsivity: Urgency, Lack of Premeditation, Lack of Perseverance, and Sensation Seeking. Current mood state was rated using the Montgomery Asberg Depression Rating Scale (MADRS), and the Young Mania Rating Scale (YMRS). Traumatic childhood experiences were assessed using the Childhood Trauma Questionnaire (CTQ). Group differences in UPPS levels; and effects of mood state and CTQ score on UPPS scores in patients were investigated.
  
  
  RESULTS
  BPD patients showed significantly higher levels of Urgency and Lack of Perseverance than BP II patients and controls, and a significantly higher level of Lack of Premeditation than controls. BP II patients showed higher levels of Urgency and Lack of Perseverance than controls. In BP II, higher MADRS scores were associated with higher impulsivity scores. Also, higher CTQ scores were associated with higher Urgency scores in BP II.
  
  
  CONCLUSIONS
  Relatively small sample size; cross-sectional assessment of influence of mood state.
  
  
  CONCLUSIONS
  BPD patients exhibited markedly elevated UPPS impulsivity scores compared with healthy controls and BP II patients, and the elevations were not related to current mood state. BP II patients showed moderately elevated impulsivity scores which were associated with a depressed mood state and to some extent with a history of childhood trauma. The findings suggest that BPD and BP II have different impulsivity profiles.
authors.affiliation: Department of Psychosomatic Medicine, Oslo University Hospital, Post Box 4950 Nydalen, Oslo 0424, Norway; Norwegian Research Network on Mood Disorders (NORMOOD), Oslo, Norway; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway. Electronic address: erboen@ous-hf.no.
authors.forename: Erlend
authors.initials: E
authors.lastname: Bøen
authors.affiliation: Department for Personality Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway; Division of Mental Health and Addiction, Department for Research and Education, Oslo University Hospital, Norway.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Hummelen
authors.affiliation: Department of Psychosomatic Medicine, Oslo University Hospital, Post Box 4950 Nydalen, Oslo 0424, Norway; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
authors.forename: Torbjørn
authors.initials: T
authors.lastname: Elvsåshagen
authors.affiliation: Department of Psychosomatic Medicine, Oslo University Hospital, Post Box 4950 Nydalen, Oslo 0424, Norway.
authors.forename: Birgitte
authors.initials: B
authors.lastname: Boye
authors.affiliation: Department of Psychosomatic Medicine, Oslo University Hospital, Post Box 4950 Nydalen, Oslo 0424, Norway; Department of Psychology, University of Oslo, Oslo, Norway.
authors.forename: Stein
authors.initials: S
authors.lastname: Andersson
authors.affiliation: Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department for Personality Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
authors.forename: Sigmund
authors.initials: S
authors.lastname: Karterud
authors.affiliation: Department of Psychosomatic Medicine, Oslo University Hospital, Post Box 4950 Nydalen, Oslo 0424, Norway; Norwegian Research Network on Mood Disorders (NORMOOD), Oslo, Norway; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
authors.forename: Ulrik F
authors.initials: UF
authors.lastname: Malt
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000523:psychology*; D001883:Borderline Personality Disorder / Q000523:psychology*; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007175:Impulsive Behavior; D008297:Male; D057566:Self Report; D011795:Surveys and Questionnaires
keywords: Bipolar II disorder; Borderline personality disorder; Impulsivity; UPPS