title: The neural control of coactivation during fatiguing contractions revisited.
abstract: In addition to the role of muscle coactivation, a major question in the field is how antagonist activation is controlled to minimize its opposing effect on agonist muscle performance. Muscle fatigue is an interesting condition to analyze the neural adjustments in antagonist muscle activity and to gain more insights into the control mechanisms of coactivation. In that context, previous studies have reported that although the EMG activity of agonists and antagonists increase in parallel, the ratio between EMG activities in the two sets of muscles during a fatiguing submaximal contraction decreased progressively and contributed to a reduction in the time to task failure. In contrast, more recent studies using a novel normalization procedure indicated that the agonist/antagonist ratio remained relatively constant, suggesting that the fatigue-related increase in coactivation does not impede performance. Current knowledge also indicates that peripheral mechanisms cannot by themselves mediate the intensity of antagonist coactivation during fatiguing contractions, implying that supraspinal mechanisms are involved. The unique modulation of the synaptic input from Ia afferents to the antagonist motor neurones during a fatiguing contraction of the agonist muscles further suggests a separate control of the two sets of muscles.
authors.affiliation: Laboratory of Applied Biology, ULB Neurosciences Institute, Université Libre de Bruxelles (ULB), Brussels, Belgium. Electronic address: jduchat@ulb.ac.be.
authors.forename: Jacques
authors.initials: J
authors.lastname: Duchateau
authors.affiliation: Laboratory of Applied Biology, ULB Neurosciences Institute, Université Libre de Bruxelles (ULB), Brussels, Belgium.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Baudry
mesh_terms: D000818:Animals; D004576:Electromyography / Q000379:methods; D006801:Humans; D007537:Isometric Contraction / Q000502:physiology*; D009046:Motor Neurons / Q000502:physiology*; D018763:Muscle Fatigue / Q000502:physiology*; D018482:Muscle, Skeletal / Q000502:physiology*
keywords: Antagonist muscle; Cortical excitability; Motor control; Spinal excitability; Surface electromyography