title: [Chronic kidney disease in Primary Health Care: prevalence and associated risk factors].
abstract: OBJECTIVE
  To determine the prevalence of chronic kidney disease and associated risk factors in subjects over 60 years of age, as well as its staging by determining the glomerular filtration rate (GFR).
  
  
  METHODS
  Cross-sectional observational study.
  
  
  METHODS
  Primary Health Care.
  
  
  METHODS
  Patients≥60 years of age who were seen in 40 Primary Health Care centres with serum creatinine measured in a central laboratory between January 1 and December 31, 2010.
  
  
  METHODS
  kidney transplant, home care.
  
  
  METHODS
  Social-demographic and anthropometric data, cardiovascular risk factors, and diseases established according to electronic clinical records. Serum creatinine was measured using standardised Jaffe kinetic method, and GFR estimated with MDRD-4-IDMS and CKD-EPI.
  
  
  RESULTS
  A total of 97,665 subjects (57.3% women, median age 70.0 years [Q1: 65.0, Q3: 77.0]). GFR-MDRD prevalence<60=15.1% (16.6% in women, 13.2% in men; P<.001) and increased with age. Multivariate analysis showed a positive association between GFR-MDRD<60 and age (OR=1.74; 95% CI 1.70 to 1.77), hypertension (OR=2.18; 95% CI 2.08 to 2.30), heart failure (OR=2.03; 95% CI 1.83 to 2.25), atrial fibrillation (OR=1.57; 95% CI 1.41 to 1.76), ischaemic heart disease (OR=1.40; 95% CI 1.30 to 1.50), peripheral arterial disease (OR=1.31; 95% CI 1.09 to 1.57), dyslipidaemia (OR=1.28; 95% CI 1.23 to 1.33), diabetes (OR=1.26; 95% CI 1.17 to 1.34), and stroke (OR=1.17; 95% CI 1.09 to 1.25). The GFR-CKD-EPI model showed an increase in OR with age and male sex, that became significant as a chronic kidney disease risk factor.
  
  
  CONCLUSIONS
  Chronic kidney disease has considerable prevalence in subjects≥60 years seen in Primary Health Care, more in women, and increasing with age. Hypertension, more than diabetes, was the main associated cardiovascular risk factor.
authors.affiliation: Equipo de Atención Primaria Florida Sud, Servei Atenció Primària Delta Llobregat, DAP Costa de Ponent, Institut Català de la Salut, L'Hospitalet de Llobregat, Barcelona, España; Grupo MACAP (Malaltia Cardiovascular en Atenció Primària), IDIAP Jordi Gol, Barcelona, España. Electronic address: bsalvador@ambitcp.catsalut.net.
authors.forename: Betlem
authors.initials: B
authors.lastname: Salvador González
authors.affiliation: Equipo de Atención Primaria Viladecans 2, Servei d'Atenció Primària Delta Llobregat, DAP Costa de Ponent, Institut Català de la Salut, Viladecans, Barcelona, España.
authors.forename: Mercedes
authors.initials: M
authors.lastname: Rodríguez Pascual
authors.affiliation: Equipo de Atención Primaria Viladecans 2, Servei d'Atenció Primària Delta Llobregat, DAP Costa de Ponent, Institut Català de la Salut, Viladecans, Barcelona, España.
authors.forename: Laura
authors.initials: L
authors.lastname: Ruipérez Guijarro
authors.affiliation: Equipo de Atención Primaria Sant Vicençs dels Horts, Servei d'Atenció Primària Baix Llobregat Centre, DAP Costa de Ponent, Institut Català de la Salut, Sant Vicenç dels Horts, Barcelona, España.
authors.forename: Antonia
authors.initials: A
authors.lastname: Ferré González
authors.affiliation: Unidad de Soporte a la Investigación, IDIAP Jordi Gol, DAP Costa de Ponent, Institut Català de la Salut, Cornellà de Llobregat, Barcelona, España.
authors.forename: Oriol
authors.initials: O
authors.lastname: Cunillera Puertolas
authors.affiliation: Servei d'Atenció Primària Baix Llobregat Centre, DAP Costa de Ponent, Institut Català de la Salut, Cornellà de Llobregat, Barcelona, España.
authors.forename: Luisa M
authors.initials: LM
authors.lastname: Rodríguez Latre
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000209:etiology; D003430:Cross-Sectional Studies; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011320:Primary Health Care; D011446:Prospective Studies; D051436:Renal Insufficiency, Chronic / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D012307:Risk Factors
keywords: Atención Primaria; Chronic kidney failure; Estimación filtrado glomerular; Glomerular filtration rate estimation; Insuficiencia renal crónica; Primary Health Care