title: "Stocking effect" in lymphoscintigraphy.
abstract: Lymphoscintigraphy following subcutaneous injection of a radiolabeled macromolecule, such as Tc-99m-nanocolloid, is used to investigate limb swelling, usually to confirm lymphedema. A well-known abnormal finding is dermal backflow, which occurs a result of diversion of lymph into skin lymphatic vessels. We describe a case in which this important sign was partially obscured by a stocking. The case also illustrates, first, the frequent though poorly recognized occurrence of lymphatic dysfunction in the clinically normal contralateral limb of a patient with unilateral swelling, and second, the principle underlying treatment with compression hosiery. Stockings should be removed before injection and all subsequent imaging.
authors.affiliation: Department of Nuclear Medicine, Royal Sussex County Hospital , Brighton, United Kingdom .
authors.forename: Georgia
authors.initials: G
authors.lastname: Keramida
authors.forename: Melissa
authors.initials: M
authors.lastname: Humphrys
authors.forename: Nicola
authors.initials: N
authors.lastname: Ryan
authors.forename: A Michael
authors.initials: AM
authors.lastname: Peters
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D061305:Lymphoscintigraphy / Q000009:adverse effects*