title: The chemistry-biology-medicine continuum and the drug discovery and development process in academia.
abstract: Admirable as it is, the drug discovery and development process is continuously undergoing changes and adjustments in search of further improvements in efficiency, productivity, and profitability. Recent trends in academic-industrial partnerships promise to provide new opportunities for advancements of this process through transdisciplinary collaborations along the entire spectrum of activities involved in this complex process. This perspective discusses ways to promote the emerging academic paradigm of the chemistry-biology-medicine continuum as a means to advance the drug discovery and development process.
authors.affiliation: Department of Chemistry, BioScience Research Collaborative, Rice University, Houston, TX 77005, USA. Electronic address: kcn@rice.edu.
authors.forename: K C
authors.initials: KC
authors.lastname: Nicolaou
mesh_terms: D000818:Animals; D001688:Biological Products / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism; D016503:Drug Delivery Systems; D055808:Drug Discovery; D006801:Humans; D018796:Immunoconjugates / Q000737:chemistry / Q000378:metabolism; D014411:Neoplastic Stem Cells / Q000166:cytology / Q000378:metabolism; D055818:Public-Private Sector Partnerships; D012106:Research; D023041:Xenograft Model Antitumor Assays
chemical_list: D001688:Biological Products; D018796:Immunoconjugates