title: Use of sodium hypochlorite for skin antisepsis before inserting a peripheral venous catheter: a pilot study.
abstract: Although it can be prevented, catheter-related bacteremia is common and dangerous. The antiseptics most widely used during insertion of peripheral venous catheters (PVCs) include povidone iodine, alcohol, and chlorhexidine. Another widely used antiseptic is a solution of 0.057 g sodium hypochlorite. This pilot study explored the contamination rate of the PVC tip inserted after skin decontamination with sodium hypochlorite. Culture analysis of the tips of the PVCs inserted into the 42 participants showed 7 (16.7%) colonized catheters. The results of this pilot study suggest taking into serious consideration the assessment of this antiseptic in randomized experimental studies.
authors.affiliation: Rizzoli Orthopedic Institute, Bologna, Italy cristiana.forni@ior.it.
authors.forename: Cristiana
authors.initials: C
authors.lastname: Forni
authors.affiliation: Rizzoli Orthopedic Institute, Bologna, Italy.
authors.forename: Tania
authors.initials: T
authors.lastname: Sabattini
authors.affiliation: Rizzoli Orthopedic Institute, Bologna, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: D'Alessandro
authors.affiliation: Rizzoli Orthopedic Institute, Bologna, Italy.
authors.forename: Ambra
authors.initials: A
authors.lastname: Fiorani
authors.affiliation: Microbiological Analysis Section, Rizzoli Orthopedic Institute, Bologna, Italy.
authors.forename: Simonetta
authors.initials: S
authors.lastname: Gamberini
authors.affiliation: Microbiological Analysis Section of the Musculoskeletal Tissue Bank, Rizzoli Orthopedic Institute, Bologna, Italy.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Maso
authors.affiliation: Laboratory of Musculoskeletal Cell Biology, Rizzoli Orthopedic Institute, Bologna, Italy.
authors.forename: Rosa
authors.initials: R
authors.lastname: Curci
authors.affiliation: Laboratory of Musculoskeletal Cell Biology, Rizzoli Orthopedic Institute, Bologna, Italy.
authors.forename: Enrichetta
authors.initials: E
authors.lastname: Zanotti
authors.affiliation: Bologna Hospital-University, Policlinico S. Orsola Malpighi, Bologna, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Chiari
mesh_terms: D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D002406:Catheterization, Peripheral; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D012867:Skin / Q000187:drug effects* / Q000382:microbiology*; D012973:Sodium Hypochlorite / Q000494:pharmacology*
chemical_list: D000891:Anti-Infective Agents, Local; D012973:Sodium Hypochlorite
keywords: antisepsis; peripheral venous catheter; sodium hypochlorite; tip contamination