title: Identification of intracellular gold nanoparticles using surface-enhanced Raman scattering.
abstract: The identification of intracellular distributions of noble metal nanoparticles is of great utility for many biomedical applications. We present an effective method to distinguish intracellular from extracellular nanoparticles by selectively quenching the SERS signals from dye molecules adsorbed onto star-shaped gold nanoparticles that have not been internalized by cells.
authors.affiliation: Department of Materials, Department of Bioengineering and Institute for Biomedical Engineering, Imperial College London, London SW7 2AZ, UK. m.stevens@imperial.ac.uk.
authors.forename: Hai-nan
authors.initials: HN
authors.lastname: Xie
authors.forename: Yiyang
authors.initials: Y
authors.lastname: Lin
authors.forename: Manuel
authors.initials: M
authors.lastname: Mazo
authors.forename: Ciro
authors.initials: C
authors.lastname: Chiappini
authors.forename: Ana
authors.initials: A
authors.lastname: Sánchez-Iglesias
authors.forename: Luis M
authors.initials: LM
authors.lastname: Liz-Marzán
authors.forename: Molly M
authors.initials: MM
authors.lastname: Stevens
mesh_terms: D000327:Adsorption; D005456:Fluorescent Dyes / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D008856:Microscopy, Fluorescence; D036103:Nanotechnology; D013059:Spectrum Analysis, Raman
chemical_list: D005456:Fluorescent Dyes; D006046:Gold