title: HIGH-THROUGHPUT CELL SORTER WITH PIEZOELECTRIC ACTUATION.
abstract: Currently, most of the integrated sorting modules in the microfabricated DEP-based and fluorescent-activated cell sorters (μFACS) still suffer from low-throughput operation and require complex fabrication process (e.g. embedded electrodes) and high power consumption (e.g. electrokinetically-driven sorters). In this paper, we demonstrate an easy-to-fabricate, low-powered and high-speed sorting module (at a single cell level) using an on-chip integrated piezoelectric (PZT) actuator. By controlling the bending motion of the PZT actuator, we have investigated and verified the high-speed flow-switching and sorting capabilities both theoretically (dynamic simulation) and experimentally using beads and biological agents.
authors.affiliation: University of California, San Diego, Electrical Engineering Department, USA.
authors.forename: C H
authors.initials: CH
authors.lastname: Chen
authors.affiliation: University of California, San Diego, Electrical Engineering Department, USA.
authors.forename: Sung H
authors.initials: SH
authors.lastname: Cho
authors.affiliation: University of California, San Diego, Electrical Engineering Department, USA.
authors.forename: A
authors.initials: A
authors.lastname: Erten
authors.affiliation: University of California, San Diego, Electrical Engineering Department, USA.
authors.forename: Y-H
authors.initials: YH
authors.lastname: Lo
keywords: Sorting; hydrodynamic; microfluidics; piezoelectric