title: A new sesquiterpene glucoside from Lysionotus pauciflorus.
abstract: A new acorane sesquiterpene glucoside, 1R,3S,4R,5R,10R-3,10-dihydroxyacoronene-3-O-beta-D-gluc-oside (1), was isolated from the EtOAc-soluble partition of the ethanol extract of Lysionotus pauciflorus, together with six known compounds, namely p-hydroxybenzoic acid (2), vanillic acid (3). caffeic acid (4). beta-hydroxypropiosyringone (5), alpha,beta-dihydroxypropiosyringone (6), and lyoniresinol (7). The structure of the new compound was elucidated on the basis of spectroscopic methods, including 1D and 2D NMR, and high-resolution MS analysis. The absolute configuration of 1 was determined from CD spectra. When evaluated against several bacterial and fungal strains, and human cancer cell lines, compound 1 and its aglycone were inactive.
authors.forename: Yaya
authors.initials: Y
authors.lastname: Wen
authors.forename: Hongjian
authors.initials: H
authors.lastname: Du
authors.forename: Yanbei
authors.initials: Y
authors.lastname: Tu
authors.forename: Wei
authors.initials: W
authors.lastname: Luo
authors.forename: Qin
authors.initials: Q
authors.lastname: Li
authors.forename: Yanfang
authors.initials: Y
authors.lastname: Li
authors.forename: Bing
authors.initials: B
authors.lastname: Liang
mesh_terms: D005960:Glucosides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D019684:Magnoliopsida / Q000737:chemistry*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry*
chemical_list: D005960:Glucosides; D010936:Plant Extracts; D012717:Sesquiterpenes