title: Is Helicobacter Pylori an endogenous source of diethyl phthalate in humans?
abstract: Monoethyl phthalate (MEP) is a metabolite used to assess exposure to diethyl phthalate (DEP). Helicobacter Pylori (HP) has been shown to produce DEP in laboratory studies. We used NHANES 1999-2000 data for 1623 adults to investigate whether HP seropositivity was associated with MEP levels. MEP levels were higher in individuals with HP seropositivity (p=0.0237), however the association differed by race. These results suggest that HP may be an endogenous source of DEP in some populations.
authors.affiliation: Department of Biological Sciences, North Carolina State University, CB 7633, Raleigh, NC 27695, United States.
authors.forename: Gina M
authors.initials: GM
authors.lastname: Hilton
authors.affiliation: Department of Biological Sciences, North Carolina State University, CB 7633, Raleigh, NC 27695, United States. Electronic address: jahoppin@ncsu.edu.
authors.forename: Jane A
authors.initials: JA
authors.lastname: Hoppin
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D016480:Helicobacter pylori / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010795:Phthalic Acids / Q000378:metabolism*; D055815:Young Adult
chemical_list: D010795:Phthalic Acids; C007379:diethyl phthalate
keywords: Diethyl phthalate; Helicobacter pylori; Microbiome; Monoethyl phthalate; NHANES