title: A new surgical triple procedure in pseudoexfoliation glaucoma using cataract surgery, Trabectome, and trabecular aspiration.
abstract: BACKGROUND
  To evaluate the potential of lowering intraocular pressure in pseudoexfoliation glaucoma with combined phacoemulsification, Trabectome, and trabecular aspiration (triple procedure) compared to phacoemulsification and trabecular aspiration alone.
  
  
  METHODS
  Using a case-matched retrospective study design, 30 patients were included into each group. The main outcome measures were the reduction of intraocular pressure and medication score at the end of follow-up. Clinical data were collected from the patients' medical records.
  
  
  RESULTS
  Mean follow-up was 15 months in both groups. Intraocular pressure decreased from 25.3 ± 6.3 mmHg to 14.4 ± 3.7 mmHg (p < 0.0001) in the triple procedure group and from 25.3 ± 4.2 mmHg to 18.1 ± 4.2 mmHg (p < 0.0001) in the control group. The medication score was lowered from 3.4 ± 1.7 to 2.1 ± 1.2 (p = 0.0017) in the triple procedure group and from 3.8 ± 1.8 to 2.3 ± 1.5 (p < 0.008) in the control group. The reduction of intraocular pressure was higher (p < 0.004) in the triple procedure group (38.4 ± 17.3 %) compared to the control group (26.8 ± 19.6 %) The reduction of the medication score did not differ significantly.
  
  
  CONCLUSIONS
  The triple procedure is more effective in lowering intraocular pressure compared to phacoemulsification and trabecular aspiration alone in pseudoexfoliation glaucoma.
authors.affiliation: Department of Ophthalmology, St. Martinus-Krankenhaus, Gladbacher Str. 26, 40219, Düsseldorf, Germany, r.widder@martinus-duesseldorf.de.
authors.forename: Randolf A
authors.initials: RA
authors.lastname: Widder
authors.forename: Sven
authors.initials: S
authors.lastname: Dinslage
authors.forename: André
authors.initials: A
authors.lastname: Rosentreter
authors.forename: Jens F
authors.initials: JF
authors.lastname: Jordan
authors.forename: Pia
authors.initials: P
authors.lastname: Kühnrich
authors.forename: Claus
authors.initials: C
authors.lastname: Cursiefen
authors.forename: Klaus-Dieter
authors.initials: KD
authors.lastname: Lemmen
authors.forename: Thomas S
authors.initials: TS
authors.lastname: Dietlein
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004322:Drainage / Q000379:methods*; D017889:Exfoliation Syndrome / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification / Q000379:methods*; D012189:Retrospective Studies; D014065:Tonometry, Ocular; D014130:Trabeculectomy / Q000379:methods*