title: Opioid misuse behaviors in adolescents and young adults in a hematology/oncology setting.
abstract: OBJECTIVE
  To describe the occurrence and psychosocial correlates of aberrant opioid-associated behavior (AOB) in adolescent and young adult (AYA) hematology and oncology patients prescribed opioid therapy.
  
  
  METHODS
  Structured retrospective chart reviews were conducted for AYA patients (N = 398) accepted for active treatment at a large pediatric hematology/oncology institution over a 17-month period. Opioid therapy was documented in the records of 94 out of the 398 patients. The records of those 94 patients were further reviewed to identify documented AOB and documented correlates of AOB.
  
  
  RESULTS
  Of the 94 patients prescribed opioid therapy, 11.7% exhibited AOB. At least one psychosocial risk factor was identified in 90.9% of patients with AOB. Concurrent use of multiple opioids was significantly associated with AOB (p = .003).
  
  
  CONCLUSIONS
  Hematology/oncology AYA patients may exhibit AOB despite a legitimate clinical indication for opioid therapy. Clinicians should consider young patients' psychosocial risk factors when using opioid therapy.
authors.affiliation: Department of Psychology, Division of Anesthesia, Department of Pediatric Medicine, and Department of Biostatistics, St. Jude Children's Research Hospital Jennifer.ehrentraut@stjude.org.
authors.forename: Jennifer Harman
authors.initials: JH
authors.lastname: Ehrentraut
authors.affiliation: Department of Psychology, Division of Anesthesia, Department of Pediatric Medicine, and Department of Biostatistics, St. Jude Children's Research Hospital.
authors.forename: Kathleen Danielle
authors.initials: KD
authors.lastname: Kern
authors.affiliation: Department of Psychology, Division of Anesthesia, Department of Pediatric Medicine, and Department of Biostatistics, St. Jude Children's Research Hospital.
authors.forename: Sarah A
authors.initials: SA
authors.lastname: Long
authors.affiliation: Department of Psychology, Division of Anesthesia, Department of Pediatric Medicine, and Department of Biostatistics, St. Jude Children's Research Hospital.
authors.forename: Angel Qi
authors.initials: AQ
authors.lastname: An
authors.affiliation: Department of Psychology, Division of Anesthesia, Department of Pediatric Medicine, and Department of Biostatistics, St. Jude Children's Research Hospital.
authors.forename: Lane G
authors.initials: LG
authors.lastname: Faughnan
authors.affiliation: Department of Psychology, Division of Anesthesia, Department of Pediatric Medicine, and Department of Biostatistics, St. Jude Children's Research Hospital.
authors.forename: Doralina L
authors.initials: DL
authors.lastname: Anghelescu
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior / Q000523:psychology; D000328:Adult; D000701:Analgesics, Opioid / Q000627:therapeutic use; D000755:Anemia, Sickle Cell / Q000453:epidemiology / Q000523:psychology*; D002648:Child; D015897:Comorbidity; D005260:Female; D006405:Hematology; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000453:epidemiology / Q000523:psychology*; D009293:Opioid-Related Disorders / Q000453:epidemiology* / Q000523:psychology*; D010146:Pain / Q000188:drug therapy* / Q000453:epidemiology / Q000523:psychology*; D012189:Retrospective Studies; D012307:Risk Factors; D012309:Risk-Taking; D055815:Young Adult
chemical_list: D000701:Analgesics, Opioid
keywords: adherence; cancer and oncology; drug abuse and exposure; hematology