title: Vogt-Koyanagi-Harada syndrome.
abstract: Vogt-Koyanagi-Harada (VKH) syndrome is a rare multisystem disease of melanocyte containing organs. It is characterized by diffuse granulomatous inflammation involving various organs including eye. VKH syndrome is usually sporadic, but some familial cases have also been reported indicating a hereditary basis. VKH is not associated with mortality but it may result in long-term complications such as decreased vision associated with cataract, glaucoma and choroidal neovascularization. For successful outcomes, early aggressive treatment using systemic steroids with gradual tapering is essential. This report describes a case of VKH syndrome in a 26-year-old male of Pakistan origin who was successfully treated with systemic steroids. The case is briefly contextualised within wider literature.
authors.affiliation: Section of Ophthalmology, Department of Surgery, The Aga Khan University Hospital, Karachi.
authors.forename: Sharmeen
authors.initials: S
authors.lastname: Akram
authors.affiliation: Section of Ophthalmology, Department of Surgery, The Aga Khan University Hospital, Karachi.
authors.forename: Khabir
authors.initials: K
authors.lastname: Khabir
mesh_terms: D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010154:Pakistan; D016896:Treatment Outcome; D014607:Uveomeningoencephalitic Syndrome / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D005938:Glucocorticoids