title: N-acyl-homoserine lactones-producing bacteria protect plants against plant and human pathogens.
abstract: The implementation of beneficial microorganisms for plant protection has a long history. Many rhizobia bacteria are able to influence the immune system of host plants by inducing resistance towards pathogenic microorganisms. In this report, we present a translational approach in which we demonstrate the resistance-inducing effect of Ensifer meliloti (Sinorhizobium meliloti) on crop plants that have a significant impact on the worldwide economy and on human nutrition. Ensifer meliloti is usually associated with root nodulation in legumes and nitrogen fixation. Here, we suggest that the ability of S. meliloti to induce resistance depends on the production of the quorum-sensing molecule, oxo-C14-HSL. The capacity to enhanced resistance provides a possibility to the use these beneficial bacteria in agriculture. Using the Arabidopsis-Salmonella model, we also demonstrate that the application of N-acyl-homoserine lactones-producing bacteria could be a successful strategy to prevent plant-originated infections with human pathogens.
authors.affiliation: Institute of Phytopathology and Applied Zoology, IFZ, Justus Liebig University Giessen, Heinrich-Buff-Ring 26-32, Giessen, 35392, Germany.
authors.forename: Casandra
authors.initials: C
authors.lastname: Hernández-Reyes
authors.forename: Sebastian T
authors.initials: ST
authors.lastname: Schenk
authors.forename: Christina
authors.initials: C
authors.lastname: Neumann
authors.forename: Karl-Heinz
authors.initials: KH
authors.lastname: Kogel
authors.forename: Adam
authors.initials: A
authors.lastname: Schikora
mesh_terms: D054742:Acyl-Butyrolactones / Q000378:metabolism*; D017360:Arabidopsis / Q000276:immunology / Q000382:microbiology; D001203:Ascomycota / Q000502:physiology; D001424:Bacterial Infections / Q000382:microbiology; D060467:Disease Resistance; D015964:Gene Expression Regulation, Bacterial; D001467:Hordeum / Q000276:immunology / Q000382:microbiology; D006801:Humans; D008969:Molecular Sequence Data; D010935:Plant Diseases / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control*; D018517:Plant Roots / Q000276:immunology / Q000382:microbiology; D012486:Salmonella typhimurium / Q000502:physiology; D016962:Sinorhizobium meliloti / Q000378:metabolism*; D014908:Triticum / Q000276:immunology / Q000382:microbiology
chemical_list: D054742:Acyl-Butyrolactones