title: Bilateral jugular vein and sigmoid sinus thrombosis related to an inherited coagulopathy: an unusual presentation.
abstract: Internal jugular vein thrombosis (IJVT) is a rare condition associated with malignancy, coagulopathy, and trauma. The optimal management of any IJVT must be individualized and depends on the condition of the patient. Case Presentation. We report the case of a 42-year-old woman with a history of a first trimester spontaneous abortion. Apart from a tension-type headache, she had no neurological symptoms. She reported an incidental diagnosis of right-sided IJVT when she was evaluated for hyperthyroidism ultrasonographically. On ultrasonography, we observed bilateral jugular vein thrombosis. The patient was started on oral warfarin. Seven months later, when she was adequately anticoagulated, she developed a second thrombosis. According to the etiological workup, she had a mutation in the homozygous methylene tetrahydrofolate reductase (MTHFR) gene and reduced protein C levels and activity. Conclusion. This report illustrates an unusual presentation of a rare condition. In this case, the etiology was associated with the coagulopathy, which occurred despite adequate anticoagulation.
authors.affiliation: Department of Neurology, Medical Faculty, Bezmi Alem Vakıf University, Adnan Menderes Boulevard, Fatih, 34093 Istanbul, Turkey.
authors.forename: Ozge
authors.initials: O
authors.lastname: Altıntaş
authors.affiliation: Department of Neurology, Medical Faculty, Bezmi Alem Vakıf University, Adnan Menderes Boulevard, Fatih, 34093 Istanbul, Turkey.
authors.forename: Azize Esra
authors.identifier: 0000-0002-8103-0927
authors.initials: AE
authors.lastname: Gürsoy
authors.affiliation: Department of Neurology, Medical Faculty, Bezmi Alem Vakıf University, Adnan Menderes Boulevard, Fatih, 34093 Istanbul, Turkey.
authors.forename: Gözde
authors.initials: G
authors.lastname: Baran
authors.affiliation: Department of Radiology, Medical Faculty, Bezmi Alem Vakıf University, Adnan Menderes Boulevard, Fatih, 34093 Istanbul, Turkey.
authors.forename: Elnur
authors.initials: E
authors.lastname: Mehdi
authors.affiliation: Department of Neurology, Medical Faculty, Bezmi Alem Vakıf University, Adnan Menderes Boulevard, Fatih, 34093 Istanbul, Turkey.
authors.forename: Talip
authors.initials: T
authors.lastname: Asil