title: Highly efficient iridium-catalyzed asymmetric hydrogenation of β-acylamino nitroolefins.
abstract: The first highly efficient Ir-catalyzed enantioselective hydrogenation of β-acylamino nitroolefins is reported. This reaction provides straightforward access to chiral β-amino nitroalkanes in high yields and excellent enantioselectivities (up to >99.9% ee) catalyzed by an Ir-(R,R)-f-spiroPhos complex.
authors.affiliation: College of Chemistry, Beijing Normal University, 19 Xinjiekouwaidajie, Beijing 100875, China. ghhou@bnu.edu.cn.
authors.forename: Qiaozhi
authors.initials: Q
authors.lastname: Yan
authors.forename: Man
authors.initials: M
authors.lastname: Liu
authors.forename: Duanyang
authors.initials: D
authors.lastname: Kong
authors.forename: Guofu
authors.initials: G
authors.lastname: Zi
authors.forename: Guohua
authors.initials: G
authors.lastname: Hou
mesh_terms: D000215:Acylation; D000473:Alkanes / Q000138:chemical synthesis* / Q000737:chemistry; D000475:Alkenes / Q000138:chemical synthesis / Q000737:chemistry*; D000586:Amination; D002384:Catalysis; D006865:Hydrogenation; D007495:Iridium / Q000737:chemistry*; D009574:Nitro Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000473:Alkanes; D000475:Alkenes; D009574:Nitro Compounds; D007495:Iridium