title: Single- and Bi-component T2* analysis of tendon before and during tensile loading, using UTE sequences.
abstract: BACKGROUND
  To determine if the application of tensile force alters the single- or bi-component T2* values of human tendons as measured on a clinical MRI scanner with ultrashort echo time (UTE sequences and if single- or bi-component T2* values differ when measured with 2D-UTE, 3D-UTE, or 3D-UTE-Cones sequences.
  
  
  METHODS
  Ten tendons were imaged before and during the application of tension using various UTE sequences at 3 Tesla. Single and bi-component T2* analysis was performed pre- and posttension and compared with Bonferroni-corrected paired Wilcoxon tests.
  
  
  RESULTS
  Range of mean pre- and posttension T2* analysis values were: short T2* fraction (78.6-79.7% and 77.3-79.7%, respectively; P = 1.0 for all sequences), long T2* fraction (20.3-21.4% and 20.3-22.7%, respectively; P = 1.0 for all sequences), short T2* (0.9-1.0 ms and 0.9 ms, respectively; P = 1.0 for all sequences), long T2* (19.9-20.4 ms and 21.9-24.0 ms, respectively; P = 0.9 for 2D-UTE and P = 1.0 for 3D-UTE and 3D-UTE-Cones), and single-component T2* (2.3-2.5 ms and 2.5-3.2 ms, respectively; P = 1.0 for all sequences).
  
  
  CONCLUSIONS
  No significant difference in single- or bi-component results was found after the application of tension to tendons. Results are similar regardless of UTE sequence used for acquisition.
authors.affiliation: Radiology Service, VA San Diego Healthcare System, San Diego, California, USA.|Department of Radiology, University of California, San Diego Medical Center, San Diego, California, USA.
authors.forename: Eric Y
authors.initials: EY
authors.lastname: Chang
authors.affiliation: Department of Radiology, University of California, San Diego Medical Center, San Diego, California, USA.
authors.forename: Jiang
authors.initials: J
authors.lastname: Du
authors.affiliation: Department of Radiology, University of California, San Diego Medical Center, San Diego, California, USA.
authors.forename: Kenyu
authors.initials: K
authors.lastname: Iwasaki
authors.affiliation: Department of Radiology, University of California, San Diego Medical Center, San Diego, California, USA.
authors.forename: Reni
authors.initials: R
authors.lastname: Biswas
authors.affiliation: Department of Radiology, University of California, San Diego Medical Center, San Diego, California, USA.
authors.forename: Sheronda
authors.initials: S
authors.lastname: Statum
authors.affiliation: Department of Radiology, University of California, San Diego Medical Center, San Diego, California, USA.
authors.forename: Qun
authors.initials: Q
authors.lastname: He
authors.affiliation: Department of Radiology, University of California, San Diego Medical Center, San Diego, California, USA.
authors.forename: Won C
authors.initials: WC
authors.lastname: Bae
authors.affiliation: Radiology Service, VA San Diego Healthcare System, San Diego, California, USA.|Department of Radiology, University of California, San Diego Medical Center, San Diego, California, USA.
authors.forename: Christine B
authors.initials: CB
authors.lastname: Chung
mesh_terms: D000369:Aged, 80 and over; D002102:Cadaver; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D013314:Stress, Mechanical; D013710:Tendons / Q000033:anatomy & histology* / Q000502:physiology*; D013718:Tensile Strength / Q000502:physiology; D016474:Weight-Bearing / Q000502:physiology*
keywords: bi-component analysis; tendon; tension; ultrashort TE