title: How to perform and assess colonic manometry and barostat study in chronic constipation.
abstract: Management of chronic constipation with refractory symptoms can be challenging. Although new drugs and behavioral treat-ments have improved outcome, when they fail, there is little guidance on what to do next. At this juncture, typically most doc-tors may refer for surgical intervention although total colectomy is associated with morbidity including complications such as recurrent bacterial overgrowth. Recently, colonic manometry with sensory/tone/compliance assessment with a barostat study has been shown to be useful. Technical challenges aside, adequate preparation, and appropriate equipment and knowledge of co-lonic physiology are keys for a successful procedure. The test itself appears to be safe with little complications. Currently, colon-ic manometry is usually performed with a 6-8 solid state or water-perfused sensor probe, although high-resolution fiber-optic colonic manometry with better spatiotemporal resolutions may become available in the near future. For a test that has evolved over 3 decades, normal physiology and abnormal findings for common phenotypes of chronic constipation, especially slow transit constipation, have been well characterized only recently largely through the advent of prolonged 24-hour ambulatory colonic manometry studies. Even though the test has been largely restricted to specialized laboratories at the moment, emerg-ing new technologies and indications may facilitate its wider use in the near future.(J Neurogastroenterol Motil 2014;20:547-552).
authors.affiliation: School of Medical Sciences, Universiti Sains Malaysia, KubangKerian, Kota Bahru, Kelantan, Malaysia.
authors.forename: Yeong Yeh
authors.initials: YY
authors.lastname: Lee
authors.affiliation: Department of Medicine, Section of Gastroenterology and Hepatology, Georgia Regents University, Augusta, Georgia, USA.
authors.forename: Askin
authors.initials: A
authors.lastname: Erdogan
authors.affiliation: Department of Medicine, Section of Gastroenterology and Hepatology, Georgia Regents University, Augusta, Georgia, USA.
authors.forename: Satish S C
authors.initials: SS
authors.lastname: Rao
keywords: Barostat; Colon; Constipation; Manometry