title: Comparative effectiveness research in clinical practice.
abstract: The Agency for Healthcare Research and Quality (AHRQ) has funded systematic reviews of comparative effectiveness research in 17 areas over the last 10 years as part of a federal mandate. These reviews provide a reliable and unbiased source of comprehensive information about the effectiveness and risks of treatment alternatives for patients and clinicians. This article describes comparative effectiveness research, provides an overview of how physicians can use it in clinical practice, and references important contributions made by the Minnesota Evidence-based Practice Center.
authors.forename: William F
authors.initials: WF
authors.lastname: Lawrence
authors.forename: Stephanie
authors.initials: S
authors.lastname: Chang
authors.forename: Robert L
authors.initials: RL
authors.lastname: Kane
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Wilt
mesh_terms: D057186:Comparative Effectiveness Research / Q000331:legislation & jurisprudence* / Q000458:organization & administration*; D019317:Evidence-Based Medicine / Q000331:legislation & jurisprudence* / Q000458:organization & administration*; D006292:Health Priorities / Q000331:legislation & jurisprudence / Q000458:organization & administration; D006302:Health Services Research / Q000331:legislation & jurisprudence / Q000458:organization & administration; D006801:Humans; D008910:Minnesota; D010043:Outcome and Process Assessment, Health Care / Q000331:legislation & jurisprudence / Q000458:organization & administration; D010353:Patient Education as Topic / Q000331:legislation & jurisprudence / Q000458:organization & administration; D017410:Practice Guidelines as Topic