title: Snake-based brain white matter fiber reconstruction.
abstract: Diffusion tensor imaging (DTI) is a tractography algorithm that provides the only means of mapping white matter fibers. Furthermore, because of its wealth of applications, diffusion MRI tractography is gaining importance in clinical and neuroscience research. This paper presents a novel brain white matter fiber reconstruction method based on the snake model by minimizing the energy function, which is composed of both external energy and internal energy. Internal energy represents the assembly of the interaction potential between connected segments, whereas external energy represents the differences between predicted DTI signals and measured DTI signals. Through comparing the proposed method with other tractography algorithms in the Fiber Cup test, the present method was shown to perform superiorly to the majority of the other methods. In fact, the proposed test performed the third best out of the ten available methods, which demonstrates that present method can accurately formulate the brain white matter fiber reconstruction.
authors.affiliation: College of Information Science and Engineering, Northeastern University, Shenyang 110000, China.
authors.forename: Meng
authors.initials: M
authors.lastname: Lu
authors.affiliation: School of Electronic and Information Engineering, Liaoning Technical University, Shenyang 110000, China.
authors.forename: Jia
authors.initials: J
authors.lastname: Di
mesh_terms: D000293:Adolescent; D000465:Algorithms; D001921:Brain / Q000473:pathology*; D056324:Diffusion Tensor Imaging / Q000379:methods*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods; D008297:Male; D009413:Nerve Fibers, Myelinated / Q000473:pathology*; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012640:Seizures / Q000473:pathology*; D012680:Sensitivity and Specificity; D066127:White Matter / Q000473:pathology*
keywords: Diffusion tensor imaging; brain white matter; energy minimization; fiber tracking; snake model