title: Total or subtotal colectomy in patients undergoing surgery for primary or recurrent epithelial ovarian cancer.
abstract: BACKGROUND
  There is controversy as to whether performing a total or subtotal colectomy is justified in patients with advanced ovarian cancer, given its potential for morbidity and a negative effect on long-term quality of life. The aim of this study was to assess the perioperative complications, mortality and outcomes of patients who underwent total or subtotal colectomy as part of the surgical procedure for primary or recurrent epithelial ovarian cancer.
  
  
  METHODS
  All patients who had undergone surgery including a total or subtotal colectomy for advanced or recurrent ovarian cancer between 2005 and 2013 at our institution were retrospectively identified.
  
  
  RESULTS
  In this time period, 339 patients underwent surgery for epithelial ovarian cancer, which in 11 (3%) patients included a total or subtotal colectomy. Severe grade 3-4 postoperative complications occurred in 3 (27%) patients, and 1 (9%) patient died within 60 days of surgery.
  
  
  CONCLUSIONS
  A total or subtotal colectomy is associated with increased but acceptable morbidity in selected patients undergoing primary cytoreductive surgery. However, in the recurrent/palliative setting, total or subtotal colectomy should be avoided as the prognosis is poor and the morbidity outweighs the clinical benefit.
authors.affiliation: Department of Obstetrics and Gynecology, Center for Integrated Oncology, University of Bonn, Germany.
authors.forename: Anton
authors.initials: A
authors.lastname: Oseledchyk
authors.forename: Alina
authors.initials: A
authors.lastname: Abramian
authors.forename: Christina
authors.initials: C
authors.lastname: Kaiser
authors.forename: Manuel
authors.initials: M
authors.lastname: Debald
authors.forename: Christian
authors.initials: C
authors.lastname: Domröse
authors.forename: Nicholas
authors.initials: N
authors.lastname: Kiefer
authors.forename: Christian
authors.initials: C
authors.lastname: Putensen
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Pantelis
authors.forename: Walther
authors.initials: W
authors.lastname: Kuhn
authors.forename: Nico
authors.initials: N
authors.lastname: Schäfer
authors.forename: Mignon-Denise
authors.initials: MD
authors.lastname: Keyver-Paik
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D003082:Colectomy / Q000401:mortality*; D065426:Cytoreduction Surgical Procedures / Q000401:mortality*; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality* / Q000601:surgery*; D010051:Ovarian Neoplasms / Q000401:mortality* / Q000601:surgery*; D010166:Palliative Care / Q000706:statistics & numerical data*; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate; D016896:Treatment Outcome