title: [Role of tamsulosin in improving double-J ureteric stent-related symptoms. A prospective multi-center, randomized study].
abstract: OBJECTIVE
  We evaluated the use of tamsulosine versus placebo for management of ureteral stent discomfort.
  
  
  METHODS
  This prospective and randomized study was realized in the Department of Urology of three university hospital. The participation was proposed at all patient having indication to receive an ureteral stent except for cancer. The evaluation of the tolerance used two validate questionnaires: Ureteral Stent Symptom Questionnaire (USSQ) and IPSS completed by each patient the day of the insertion, next day, one week later and the day before and after the removal. The main assessment criterion was the question "global quality of life" one week after the stent insertion.
  
  
  RESULTS
  Seventy-nine patients were randomized between June, 2010 and October, 2012. Despite phone reminders only 38 (48.1%) were complete questionnaires. Out of 39, 18 patients in the tamsulosine group and out of 40, 20 in the phloroglucinol group. The majority of the patients (92%) were included for stone disease. There is not significant difference between the 2 groups using the USSQ and IPSS at day+1, day+7, pre-ablation and day+1 ablation. A significant improvement of the scores was noted to day+1 by the ablation of the JJ in 2 groups.
  
  
  CONCLUSIONS
  Our study did not show superiority of tamsulosine versus placebo in the improvement of the tolerance of ureteral stent.
  
  
  METHODS
  2.
authors.affiliation: Service d'urologie, CHRU Bretonneau, 2, boulevard Tonnelé, 37000 Tours, France. Electronic address: marcvava@hotmail.fr.
authors.forename: M
authors.initials: M
authors.lastname: Valiere Vialeix
authors.affiliation: Centre hospitalier régional La Rochelle, rue du Docteur-Schweitzer, 17019 La Rochelle cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Puichaud
authors.affiliation: CHU de Poitiers, 2, rue de la Milétrie, 86021 Poitiers cedex, France.
authors.forename: J
authors.initials: J
authors.lastname: Irani
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000209:etiology* / Q000517:prevention & control*; D011446:Prospective Studies; D011474:Prosthesis Design; D015607:Stents / Q000009:adverse effects*; D013449:Sulfonamides / Q000627:therapeutic use*; D011795:Surveys and Questionnaires; D000077409:Tamsulosin; D014513:Ureter
chemical_list: D013449:Sulfonamides; D000077409:Tamsulosin
keywords: Sonde urétérale; Symptoms; Symptômes; Tamsulosin; Tamsulosine; Traitement; Treatment; Ureteral stent