title: Effect of hemoperfusion cartridge on different internal environmental indicators.
abstract: BACKGROUND
  This study aimed to observe the effect of hemoperfusion (HP) cartridge on different internal environment indicators at different time points in patients with acute blood poisoning and to find alternative indicators for the detection of blood poisoning.
  
  
  METHODS
  The levels of internal environment indicators (blood pH, PvCO2, PvO2, blood lactate, potassium, free calcium, bicarbonate, and blood glucose) before and after HP treatment were recorded for patients with acute poisoning at time points of 30 minutes and 120 minutes. After calculating the difference value δ, the statistical software was used to analyze the statistical difference of the influence caused by HP cartridge at two time points. According to the formula, adsorption rate % = ×100, the adsorption rate of each indicator was calculated respectively.
  
  
  RESULTS
  The difference of indicators at different time points in inlet and outlet such as blood glucose, free-calcium, and lactate was statistically significant (P<0.05), but the difference in indicators such as pH, PvCO2, PvO2, potassium, sodium, and bicarbonate was not statistically significant (P>0.05).
  
  
  CONCLUSIONS
  During HP treatment, the indicators of blood glucose, free-calcium and lactate were significantly affected by HP cartridge, and the effect varies with time.
authors.affiliation: Department of Emergency Medicine, Tianjin Medical University General Hospital, Tianjin 300052, China.
authors.forename: Li-Jun
authors.initials: LJ
authors.lastname: Wang
authors.affiliation: Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China ; Rwanda Bureau of Standards, The Republic of Rwanda.
authors.forename: Nyirimigabo
authors.initials: N
authors.lastname: Eric
authors.affiliation: Department of Emergency Medicine, Tianjin Medical University General Hospital, Tianjin 300052, China.
authors.forename: Mu-Ming
authors.initials: MM
authors.lastname: Yu
authors.affiliation: Department of Emergency Medicine, Tianjin Medical University General Hospital, Tianjin 300052, China.
authors.forename: Yan-Fen
authors.initials: YF
authors.lastname: Chai
keywords: Adsorption rate; Blood glucose; Hemoperfusion cartridge; Internal environment indicators