title: Recombinant human bone morphogenetic protein 2 in augmentation procedures: case reports.
abstract: To successfully rehabilitate edentulous patients using endosseous implants, there must be enough available bone. Several techniques have been proposed for augmentation of sites with insufficient bone volume. Although autogenous bone has long been considered the gold standard for such procedures, the limited availability of graft material and a high morbidity rate are potential disadvantages of this type of graft. An alternative is to use recombinant human bone morphogenetic protein 2 (rhBMP-2), which is able to support bone regeneration in the oral environment. These cases demonstrate the applicability of rhBMP-2 in maxillary sinus elevation and augmentation procedures in the maxilla to enable dental implant placement. The use of rhBMP-2 in alveolar augmentation procedures had several clinical benefits for these patients.
authors.forename: Jaques
authors.initials: J
authors.lastname: Luiz
authors.forename: Luis Eduardo Marques
authors.initials: LE
authors.lastname: Padovan
authors.forename: Marcela
authors.initials: M
authors.lastname: Claudino
mesh_terms: D000328:Adult; D000368:Aged; D055396:Bone Morphogenetic Protein 2 / Q000627:therapeutic use*; D001861:Bone Regeneration / Q000187:drug effects; D018786:Bone Substitutes / Q000627:therapeutic use*; D003094:Collagen; D003758:Dental Implantation, Endosseous / Q000379:methods; D015921:Dental Implants; D019094:Dental Prosthesis, Implant-Supported; D003827:Denture, Complete, Upper; D005260:Female; D005500:Follow-Up Studies; D005781:Gelatin Sponge, Absorbable / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008437:Maxilla / Q000601:surgery; D008443:Maxillary Sinus / Q000601:surgery; D008567:Membranes, Artificial; D008875:Middle Aged; D008903:Minerals / Q000627:therapeutic use; D011994:Recombinant Proteins / Q000627:therapeutic use; D059546:Sinus Floor Augmentation / Q000379:methods*; D013526:Surgical Mesh; D014025:Titanium / Q000737:chemistry; D016212:Transforming Growth Factor beta / Q000627:therapeutic use*
chemical_list: C077540:Bio-Oss; D055396:Bone Morphogenetic Protein 2; D018786:Bone Substitutes; D015921:Dental Implants; D008567:Membranes, Artificial; D008903:Minerals; D011994:Recombinant Proteins; D016212:Transforming Growth Factor beta; C499469:recombinant human bone morphogenetic protein-2; D003094:Collagen; D014025:Titanium