title: Love is in the Aire: mTECs share their assets.
abstract: Self-tolerance imposition requires the presentation of self-antigens by a variety of thymic antigen-presenting cells. In this issue of Immunity, Perry et al. (2014) reveal unidirectional self-antigen transfer from medullary thymic epithelial cells to dendritic cells as an essential aspect.
authors.affiliation: Division of Developmental Immunology, German Cancer Research Center, 69120 Heidelberg, Germany. Electronic address: b.kyewski@dkfz.de.
authors.forename: Bruno
authors.initials: B
authors.lastname: Kyewski
authors.affiliation: Helmholtz Young Investigator Group Immune Tolerance, Tumor Immunology Program, German Cancer Research Center, 69120 Heidelberg, Germany.
authors.forename: Markus
authors.initials: M
authors.lastname: Feuerer
mesh_terms: D000818:Animals; D001854:Bone Marrow Cells / Q000276:immunology*; D016693:Receptors, Antigen, T-Cell, alpha-beta / Q000276:immunology*; D017634:Self Tolerance / Q000276:immunology*; D013950:Thymus Gland / Q000276:immunology*; D014157:Transcription Factors / Q000235:genetics*; D000096927:AIRE Protein
chemical_list: D016693:Receptors, Antigen, T-Cell, alpha-beta; D014157:Transcription Factors; D000096927:AIRE Protein