title: circBase: a database for circular RNAs.
abstract: Recently, several laboratories have reported thousands of circular RNAs (circRNAs) in animals. Numerous circRNAs are highly stable and have specific spatiotemporal expression patterns. Even though a function for circRNAs is unknown, these features make circRNAs an interesting class of RNAs as possible biomarkers and for further research. We developed a database and website, "circBase," where merged and unified data sets of circRNAs and the evidence supporting their expression can be accessed, downloaded, and browsed within the genomic context. circBase also provides scripts to identify known and novel circRNAs in sequencing data. The database is freely accessible through the web server at http://www.circbase.org/.
authors.affiliation: Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany.
authors.forename: Petar
authors.initials: P
authors.lastname: Glažar
authors.affiliation: Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany.
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Papavasileiou
authors.affiliation: Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany rajewsky@mdc-berlin.de.
authors.forename: Nikolaus
authors.initials: N
authors.lastname: Rajewsky
mesh_terms: D000818:Animals; D030541:Databases, Genetic; D006801:Humans; D020407:Internet; D012313:RNA; D000079962:RNA, Circular; D017423:Sequence Analysis, RNA; D014584:User-Computer Interface
chemical_list: D000079962:RNA, Circular; D012313:RNA
keywords: circular RNA; database; gene expression