title: A small-sized graphene oxide supramolecular assembly for targeted delivery of camptothecin.
abstract: A small-sized graphene oxide supramolecular assembly was obtained by the inclusion complexation of hyaluronated adamantane with β-cyclodextrin and the π-stacking of graphene oxide with camptothecin, exhibiting an excellent stability in the serum environment and a higher inhibition effect toward malignant cells than a free drug.
authors.affiliation: Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300071, P. R. China. yuliu@nankai.edu.cn.
authors.forename: Ying-Ming
authors.initials: YM
authors.lastname: Zhang
authors.forename: Yu
authors.initials: Y
authors.lastname: Cao
authors.forename: Yang
authors.initials: Y
authors.lastname: Yang
authors.forename: Jia-Tong
authors.initials: JT
authors.lastname: Chen
authors.forename: Yu
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000218:Adamantane / Q000737:chemistry; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000633:toxicity; D002166:Camptothecin / Q000737:chemistry* / Q000633:toxicity; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D004337:Drug Carriers / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D006820:Hyaluronic Acid / Q000737:chemistry; D051379:Mice; D041681:NIH 3T3 Cells; D010087:Oxides / Q000737:chemistry; D047392:beta-Cyclodextrins / Q000737:chemistry
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004337:Drug Carriers; D010087:Oxides; D047392:beta-Cyclodextrins; D006108:Graphite; D006820:Hyaluronic Acid; C031215:betadex; D000218:Adamantane; D002166:Camptothecin