title: HERG-targeted therapy in both cancer and cardiovascular system with cardiovascular drugs.
authors.affiliation: Cardiologia Ospedale San Vincenzo - Taormina (Me) Azienda Sanitaria Provinciale di Messina, Contrada Sirina, 98039 Taormina (Messina), Italy. Electronic address: patane-@libero.it.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Patanè
mesh_terms: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000037:antagonists & inhibitors / Q000378:metabolism; D000818:Animals; D002317:Cardiovascular Agents / Q000008:administration & dosage* / Q000378:metabolism; D002319:Cardiovascular System / Q000187:drug effects* / Q000378:metabolism; D000072237:ERG1 Potassium Channel; D051638:Ether-A-Go-Go Potassium Channels / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000378:metabolism
chemical_list: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D002317:Cardiovascular Agents; D000072237:ERG1 Potassium Channel; D051638:Ether-A-Go-Go Potassium Channels; C000606913:KCNH2 protein, human
keywords: Cancer chemotherapy; Cardio-oncology; Cardiotoxicity; HERG; Multidrug resistance (MDR); Torsade de pointes arrhythmia(TdP)