title: Systems cell biology.
abstract: Systems cell biology melds high-throughput experimentation with quantitative analysis and modeling to understand many critical processes that contribute to cellular organization and dynamics. Recently, there have been several advances in technology and in the application of modeling approaches that enable the exploration of the dynamic properties of cells. Merging technology and computation offers an opportunity to objectively address unsolved cellular mechanisms, and has revealed emergent properties and helped to gain a more comprehensive and fundamental understanding of cell biology.
authors.affiliation: Seattle Biomedical Research Institute, Seattle, WA 98109 Institute for Systems Biology, Seattle, WA 98109.
authors.forename: Fred D
authors.initials: FD
authors.lastname: Mast
authors.affiliation: Seattle Biomedical Research Institute, Seattle, WA 98109 Institute for Systems Biology, Seattle, WA 98109.
authors.forename: Alexander V
authors.initials: AV
authors.lastname: Ratushny
authors.affiliation: Seattle Biomedical Research Institute, Seattle, WA 98109 Institute for Systems Biology, Seattle, WA 98109 john.aitchison@seattlebiomed.org.
authors.forename: John D
authors.initials: JD
authors.lastname: Aitchison
mesh_terms: D035843:Biomedical Research; D003585:Cell Biology; D003584:Cytological Techniques / Q000379:methods*; D059014:High-Throughput Nucleotide Sequencing; D008954:Models, Biological; D040901:Proteomics; D012107:Research Design; D049490:Systems Biology / Q000379:methods*