title: Endoscopic full-thickness resection for gastrointestinal lesions using the over-the-scope clip system: a case series.
abstract: The over-the-scope clip (OTSC) system was developed for the closure of gastrointestinal defects but can also be used for endoscopic resection. This report describes the efficacy and safety of endoscopic full-thickness resection (eFTR) using the OTSC system. In this retrospective, observational, open-label case study, a total of 17 patients underwent eFTR using a dual clip and cap technique. The indications were: carcinoids, incompletely resected colon cancers involving the mucosa or submucosa, recurrent fibrosed adenoma of the colon, and submucosal lesions. The technical success was 94 % (16 /17). The complete resection (R0) rate was 100 %. There were no complications. In summary, the described minimally invasive method to perform eFTR of complex gastrointestinal lesions appears to be effective and safe.
authors.affiliation: Interventional Endoscopy, Department of Gastroenterology, Klinikum Dortmund, Dortmund, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Fähndrich
authors.affiliation: Interventional Endoscopy, Department of Gastroenterology, Klinikum Dortmund, Dortmund, Germany.
authors.forename: Marcel
authors.initials: M
authors.lastname: Sandmann
mesh_terms: D000236:Adenoma / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002276:Carcinoid Tumor / Q000601:surgery*; D003110:Colonic Neoplasms / Q000601:surgery; D016099:Endoscopy, Gastrointestinal / Q000295:instrumentation* / Q000379:methods; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome