title: Is there an association between a history of placental abruption and long-term maternal renal complications?
abstract: OBJECTIVE
  To investigate whether patients with a history of placental abruption have an increased risk for subsequent maternal long-term morbidity.
  
  
  METHODS
  A population-based study compared the incidence of long-term renal morbidity in cohort of women with and without a history of placental abruption. Deliveries occurred during a 25-year period, with a mean follow-up duration of 11.2 years. Renal morbidity included kidney transplantation, chronic renal failure, hypertensive renal disease, etc.
  
  
  RESULTS
  During the study period 99 354 deliveries met the inclusion criteria; 1.8% (n = 1807) occurred in patients with a diagnosis of placental abruption. Patients with placental abruption did not have higher cumulative incidence of renal related hospitalizations, using Kaplan-Meier survival curve. During the follow-up period patients with a history of placental abruption did not have higher rate of renal morbidity (0.2% versus 0.1%; OR 1.8; 95% CI 0.6-4.8; p = 0.261). When performing a Cox proportional hazards model, adjusted for confounders such as parity and diabetes mellitus, a history of placental abruption was not associated with renal related hospitalizations (adjusted HR, 1.6; 95% CI, 0.6-4.2; p = 0.381).
  
  
  CONCLUSIONS
  Placental abruption, even though considered a part of the "placental syndrome" with possible vascular etiology, is not a risk factor for long-term maternal renal complications.
authors.affiliation: a Department of Obstetrics and Gynecology , Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev , Beer-Sheva , Israel and.
authors.forename: E S
authors.initials: ES
authors.lastname: Arazi
authors.forename: R
authors.initials: R
authors.lastname: Kessous
authors.forename: I
authors.initials: I
authors.lastname: Shoham-Vardi
authors.forename: G
authors.initials: G
authors.lastname: Pariente
authors.forename: R
authors.initials: R
authors.lastname: Sergienko
authors.forename: E
authors.initials: E
authors.lastname: Sheiner
mesh_terms: D000037:Abruptio Placentae; D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007557:Israel; D053208:Kaplan-Meier Estimate; D011247:Pregnancy; D016016:Proportional Hazards Models; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology / Q000209:etiology*; D012189:Retrospective Studies; D012307:Risk Factors
keywords: Obstetric complication; placental abruption; renal morbidity