title: Correlation Between Hypertension, C-Reactive Protein and Serum Uric Acid With Psychological Well-being.
abstract: BACKGROUND
  Multiple population-based human studies have established a strong association between increasing levels of serum C-reactive protein, uric acid and subsequent development of hypertension.
  
  
  OBJECTIVE
  We aimed to investigate the association between mental well-being with presence of hypertension, hyperuricemia and hs-CRP levels. ‬‬
  
  
  METHODS
  This was a cross sectional study of 801 individuals aged 35-85 years old in Broujerd, Iran, included by randomized cluster sampling. General Health Questionnaire (GHQ-12) for assessing mental health/distress level, MONICA standard questions for evaluating hypertension history, serum hs-CRP and Serum Uric Acid (SUA) were evaluated Data were analyzed by appropriate statistical test such as chi-square, T-test and correlation.
  
  
  RESULTS
  One hundred eighty five patients (23.1%) had high distress/minor psychiatric disorders. SUA had significant association with hypertension (r = 0.64, P = 0.034). No significant relation was observed between hs-CRP and hypertension. The correlation between GHQ and hs-CRP was not significant but a weak and negative correlation was found between GHQ and SUA SUA (P = 0.012, r = -0.089).
  
  
  CONCLUSIONS
  The weak and strong correlation among these parameters indicate that mental wellbeing relays on physical wellness and interact with each other; therefore, controlling hypertension along with uric acid control may effect mental health of any kind of patients.
authors.affiliation: School of Medicine, Lorestan University of Medical Sciences, Khorramabad, IR Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Maleki
authors.affiliation: Psychiatry Research Center, Isfahan University of Medical Sciences, Isfahan, IR Iran.
authors.forename: Saeid
authors.initials: S
authors.lastname: Samandari
authors.affiliation: School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Australia.
authors.forename: Osvaldo
authors.initials: O
authors.lastname: Almeida
authors.affiliation: Students Scientific Research Center, Tehran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Scott Reza
authors.initials: SR
authors.lastname: Jafarian Kerman
authors.affiliation: Azna Health Services Center, Lorestan University of Medical Sciences, Azna, IR Iran.
authors.forename: Mahdi
authors.initials: M
authors.lastname: Abdolvand
authors.affiliation: Imam Khomeini Hospital, Lorestan University of Medical Sciences, Borujerd, IR Iran.
authors.forename: Farshid
authors.initials: F
authors.lastname: Aliyari
authors.affiliation: School of Nursing, Lorestan University of Medical Sciences, Aligudarz, IR Iran.
authors.forename: Saeid
authors.initials: S
authors.lastname: Foroughi
keywords: C - Reactive Protein; Hypertension; Mental Health; Uric Acid