title: Better clinical results after closed- compared to open-wedge high tibial osteotomy in patients with medial knee osteoarthritis and varus leg alignment.
abstract: OBJECTIVE
  Studies comparing mid- or long-term outcomes of open- and closed-wedge high tibial osteotomy are limited. Here, the midterm survival rate and clinical and radiographic outcomes were compared for these two techniques. The study hypothesis, based on short-term follow-up, was that after midterm follow-up, the two techniques would not differ.
  
  
  METHODS
  A prospective follow-up study was conducted for a previously reported randomized controlled trial of an original 50 patients (25 open-wedge osteotomy and 25 closed-wedge osteotomy) with medial knee osteoarthritis and a varus leg alignment. We analyzed patients without knee arthroplasty (mean age 48.7 years, SD 8.0) for clinical and radiographic follow-up.
  
  
  RESULTS
  Five patients in each group had undergone conversion to a total knee arthroplasty or unicompartmental knee arthroplasty, leaving 19 patients for analysis in each group. At 7.9 years of follow-up (range 7-9 years), survival did not differ significantly between groups (open-wedge group 81.3% [95% confidence interval (CI) 75.2-100], closed-wedge group 82.0% [95% CI 66.7-100]). At final follow-up, total Dutch Western Ontario and McMaster Universities Arthritis (WOMAC), Knee Society Score, and visual analog scale (VAS) pain did not differ between groups. However, the results were significantly better in the closed-wedge group for VAS satisfaction and WOMAC pain and stiffness compared to the open-wedge group. Radiographic evaluation did not differ between groups for any outcome at final follow-up.
  
  
  CONCLUSIONS
  After a mean follow-up of 7.9 years, patients undergoing a closed-wedge osteotomy had favorable clinical results compared to those who underwent an open-wedge osteotomy.
  
  
  METHODS
  II.
authors.affiliation: Department of Orthopaedics, Radboud University Medical Centre, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands. Nienkevanegmond@hotmail.com.
authors.forename: N
authors.initials: N
authors.lastname: van Egmond
authors.affiliation: Department of Orthopaedics, Rijnstate Hospital Arnhem, Wagnerlaan 55, 6800 TA, Arnhem, The Netherlands.
authors.forename: S
authors.initials: S
authors.lastname: van Grinsven
authors.affiliation: Department of Orthopaedics, Rijnstate Hospital Arnhem, Wagnerlaan 55, 6800 TA, Arnhem, The Netherlands.
authors.forename: C J M
authors.initials: CJ
authors.lastname: van Loon
authors.affiliation: Department of Orthopaedics and Traumatology, Meander Medical Center, P.O. Box 1502, 3800 BM, Amersfoort, The Netherlands.
authors.forename: R D
authors.initials: RD
authors.lastname: Gaasbeek
authors.affiliation: Department of Orthopaedics, Radboud University Medical Centre, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
authors.forename: A
authors.initials: A
authors.lastname: van Kampen
mesh_terms: D000328:Adult; D017760:Bone Malalignment / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007719:Knee Joint / Q000601:surgery; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000601:surgery*; D010027:Osteotomy / Q000379:methods*; D011446:Prospective Studies; D013977:Tibia / Q000601:surgery*
keywords: Closed-wedge high tibial osteotomy; Knee; Open-wedge high tibial osteotomy; Osteoarthritis; RCT