title: Myocarditis in drug rash with eosinophilia and systemic symptoms.
abstract: Drug rash with eosinophilia and systemic symptoms is a drug hypersensitivity reaction. Hepatitis and nephritis are the most common visceral manifestations. Myocarditis is important to recognise, given the high mortality rate. We describe a child with drug rash with eosinophilia and systemic symptoms and discuss the role of N-terminal pro-hormone of basic natriuretic peptide in early recognition of associated myocarditis.
authors.affiliation: 1Department of Pediatrics,Keck School of Medicine,Los Angeles County + University of Southern California Medical Center,Los Angeles,California,United States of America.
authors.forename: Cynthia H
authors.initials: CH
authors.lastname: Ho
authors.affiliation: 1Department of Pediatrics,Keck School of Medicine,Los Angeles County + University of Southern California Medical Center,Los Angeles,California,United States of America.
authors.forename: Merujan Y
authors.initials: MY
authors.lastname: Uzunyan
mesh_terms: D002675:Child, Preschool; D003875:Drug Eruptions / Q000209:etiology*; D004802:Eosinophilia / Q000097:blood*; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000009:adverse effects* / Q000627:therapeutic use; D009080:Mucocutaneous Lymph Node Syndrome / Q000188:drug therapy*; D009205:Myocarditis / Q000188:drug therapy*
chemical_list: D016756:Immunoglobulins, Intravenous
keywords: Drug-induced hypersensitivity syndrome; N-terminal pro-hormone of basic natriuretic peptide; drug rash with eosinophilia and systemic symptoms; drug-induced hypersensitivity syndrome; eosinophilic myocarditis