title: Intrapartum interventions for singleton pregnancies arising from assisted reproductive technologies.
abstract: OBJECTIVE
  To assess whether singleton pregnancies conceived by assisted reproductive technology (ART) are associated with an increased use of intrapartum interventions when compared with spontaneous singleton pregnancies.
  
  
  METHODS
  In total, 1327 ART pregnancies and 5222 spontaneous pregnancies during the period 2004 to 2008 were extracted from BORN (Better Outcomes Registry and Network) Ontario's information system. The incidences of common intrapartum interventions were compared, and different classification systems for Caesarean section were used to compare the indications for these between singleton pregnancies following ART with or without intracytoplasmic sperm injection and singleton spontaneously conceived pregnancies.
  
  
  RESULTS
  Compared with spontaneous singleton pregnancies, the ART group had increased incidences of internal electronic fetal monitoring (OR 1.60; 95% CI 1.37 to 1.87), artificial rupture of membranes (OR 1.39; 95% CI 1.17 to 1.66), oxytocin augmentation of labour (OR 1.51; 95% CI 1.28 to 1.77), induction of labour (OR 1.31; 95% CI 1.14 to 1.50), and Caesarean section (OR 1.40; 95% CI 1.24 to 1.60).
  
  
  CONCLUSIONS
  Singleton pregnancies resulting from ART were associated with more frequent use of several intrapartum interventions, including Caesarean section.
authors.affiliation: School of Public Health, Fudan University, Shanghai, China; Fetal Medicine Unit, Division of Maternal-Fetal Medicine, Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Shanghai, China; OMNI Research Group, Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa ON.
authors.forename: Lu-Ming
authors.initials: LM
authors.lastname: Sun
authors.affiliation: OMNI Research Group, Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa ON; Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa ON.
authors.forename: Andrea
authors.initials: A
authors.lastname: Lanes
authors.affiliation: Placenta Clinic, Maternal-Fetal Medicine Division, Department of Obstetrics and Gynecology, Mount Sinai Hospital, University of Toronto, Toronto ON.
authors.lastname: Kingdom
authors.affiliation: OMNI Research Group, Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa ON.
authors.forename: Huiling
authors.initials: H
authors.lastname: Cao
authors.affiliation: Department of Epidemiology, Biostatistics and Occupational Health and Department of Pediatrics, McGill University Faculty of Medicine, Montreal QC.
authors.forename: Michael
authors.initials: M
authors.lastname: Kramer
authors.affiliation: OMNI Research Group, Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa ON; Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa ON.
authors.forename: Shi Wu
authors.initials: SW
authors.lastname: Wen
authors.affiliation: Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Faculty of Medicine, Ottawa General Hospital, University of Ottawa, Ottawa ON.
authors.forename: Junqing
authors.initials: J
authors.lastname: Wu
authors.affiliation: Shanghai Institute of Planned Parenthood Research/WHO Collaborating Center on Human Research, Shanghai, China.
authors.forename: Yue
authors.initials: Y
authors.lastname: Chen
authors.affiliation: OMNI Research Group, Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa ON; Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa ON.
authors.forename: Mark C
authors.initials: MC
authors.lastname: Walker
mesh_terms: D000328:Adult; D002170:Canada / Q000453:epidemiology; D015148:Cardiotocography / Q000379:methods / Q000706:statistics & numerical data; D002585:Cesarean Section / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D015994:Incidence; D007751:Labor, Induced / Q000379:methods / Q000706:statistics & numerical data; D011247:Pregnancy; D011248:Pregnancy Complications / Q000145:classification / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D011256:Pregnancy Outcome / Q000453:epidemiology; D027724:Reproductive Techniques, Assisted / Q000706:statistics & numerical data*; D056826:Single Embryo Transfer / Q000009:adverse effects / Q000379:methods; D020554:Sperm Injections, Intracytoplasmic / Q000009:adverse effects / Q000379:methods
keywords: assisted reproductive technologies; intrapartum interventions; singleton pregnancies