title: Polycystic ovary syndrome and risk of endometrial cancer: a mini-review.
abstract: The polycystic ovary syndrome is the most common endocrinological disorder of reproductive age women with a prevalence of 5 to 8 %. The most common diagnostic criteria used for polycystic ovary syndrome are oligo- or an-ovulation, clinical and/ or biochemical signs of hyperandrogenism and polycystic ovaries. Hyperandrogenism results in increased estrogen levels and lack of cyclic progesterone due to anovulation and persistent stimulation of the endometrium may lead to endometrial hyperplasia or adenocarcinoma development. In this mini review, we aimed to evaluate the possible relationship between polycystic ovary syndrome and endometrial cancer.
authors.affiliation: Obstetrics and Gynecology Department, Dr Zekai Tahir Burak Woman's Health Education and Research Hospital, Ankara, Turkey E-mail : kuntaykokanali@gmail.com.
authors.forename: Aytekin
authors.initials: A
authors.lastname: Tokmak
authors.forename: Mahmut Kuntay
authors.initials: MK
authors.lastname: Kokanali
authors.forename: Ali Irfan
authors.initials: AI
authors.lastname: Guzel
authors.forename: Aydan
authors.initials: A
authors.lastname: Kara
authors.forename: Hasan Onur
authors.initials: HO
authors.lastname: Topcu
authors.forename: Sabri
authors.initials: S
authors.lastname: Cavkaytar
mesh_terms: D000230:Adenocarcinoma / Q000453:epidemiology*; D004714:Endometrial Hyperplasia / Q000453:epidemiology*; D016889:Endometrial Neoplasms / Q000453:epidemiology*; D005260:Female; D006801:Humans; D011085:Polycystic Ovary Syndrome / Q000453:epidemiology*; D012306:Risk