title: Benzannulation of indoles to carbazoles and its applications for syntheses of carbazole alkaloids.
abstract: A novel and efficient method for the benzannulation of indoles to carbazoles is reported. γ-Carbonyl tert-butylperoxide is applied as a new diene building block for the π-extension of simple indoles. The synthetic utility of this method is demonstrated by concise and selective total syntheses of naturally occurring carbazole alkaloids, olivacine, and asteropusazole A.
authors.affiliation: Department of Chemistry, Renmin University of China , Beijing 100872, China.
authors.forename: Xiaojian
authors.initials: X
authors.lastname: Zheng
authors.forename: Leiyang
authors.initials: L
authors.lastname: Lv
authors.forename: Shenglin
authors.initials: S
authors.lastname: Lu
authors.forename: Wenxiao
authors.initials: W
authors.lastname: Wang
authors.forename: Zhiping
authors.initials: Z
authors.lastname: Li
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D002227:Carbazoles / Q000138:chemical synthesis* / Q000737:chemistry; D004611:Ellipticines / Q000138:chemical synthesis* / Q000737:chemistry; D007211:Indoles / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000470:Alkaloids; D002227:Carbazoles; D004611:Ellipticines; D007211:Indoles; C000593346:asteropusazole A; C011521:olivacine