title: Ceramic nanoparticles: Recompense, cellular uptake and toxicity concerns.
abstract: Over the past few years, nanoparticles and their role in drug delivery have been the centre of attraction as new drug delivery systems. Various forms of nanosystems have been designed, such as nanoclays, scaffolds and nanotubes, having numerous applications in areas such as drug loading, target cell uptake, bioassay and imaging. The present study discusses various types of nanoparticles, with special emphasis on ceramic nanocarriers. Ceramic materials have high mechanical strength, good body response and low or non-existing biodegradability. In this article, the various aspects concerning ceramic nanoparticles, such as their advantages over other systems, their cellular uptake and toxicity concerns are discussed in detail.
authors.affiliation: a Pharmaceutical Biotechnology Laboratory, University Institute of Pharmacy, Pt. Ravishankar Shukla University , Raipur , Chhattisgarh , India.
authors.forename: Deependra
authors.initials: D
authors.lastname: Singh
authors.affiliation: a Pharmaceutical Biotechnology Laboratory, University Institute of Pharmacy, Pt. Ravishankar Shukla University , Raipur , Chhattisgarh , India.
authors.forename: Satpal
authors.initials: S
authors.lastname: Singh
authors.affiliation: a Pharmaceutical Biotechnology Laboratory, University Institute of Pharmacy, Pt. Ravishankar Shukla University , Raipur , Chhattisgarh , India.
authors.forename: Jageshwari
authors.initials: J
authors.lastname: Sahu
authors.affiliation: a Pharmaceutical Biotechnology Laboratory, University Institute of Pharmacy, Pt. Ravishankar Shukla University , Raipur , Chhattisgarh , India.
authors.forename: Shikha
authors.initials: S
authors.lastname: Srivastava
authors.affiliation: a Pharmaceutical Biotechnology Laboratory, University Institute of Pharmacy, Pt. Ravishankar Shukla University , Raipur , Chhattisgarh , India.
authors.forename: Manju Rawat
authors.initials: MR
authors.lastname: Singh
mesh_terms: D000537:Aluminum Oxide / Q000737:chemistry; D002130:Calcium Phosphates / Q000737:chemistry; D002516:Ceramics / Q000737:chemistry* / Q000493:pharmacokinetics / Q000633:toxicity; D004337:Drug Carriers / Q000737:chemistry* / Q000493:pharmacokinetics / Q000633:toxicity; D004339:Drug Compounding; D065546:Drug Liberation; D005290:Ferric Compounds / Q000737:chemistry; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry* / Q000633:toxicity; D036103:Nanotechnology / Q000379:methods*; D012822:Silicon Dioxide / Q000737:chemistry; D014025:Titanium / Q000737:chemistry; D015040:Zirconium / Q000737:chemistry
chemical_list: D002130:Calcium Phosphates; D004337:Drug Carriers; D005290:Ferric Compounds; C009495:titanium dioxide; C000499:ferric oxide; D012822:Silicon Dioxide; D015040:Zirconium; D014025:Titanium; D000537:Aluminum Oxide
keywords: cellular uptake; ceramic nanocarriers; nanoparticles; nanosystems; toxicity