title: A method for in vivo detection of abnormal subepidermal tissues based on dielectric properties.
abstract: In this paper, a convenient and noninvasive scanning imaging method using microwave frequency band for abnormal subepidermal tissues detection is proposed in the aim to improve diagnosis and prognosis in clinical environments. This method is based on the reflective detection technology with coaxial probe that is used to measure the dielectric properties of tissues. An improved equivalent circuit and simulated annealing algorithm (SA) were used in this work to analyze the dielectric properties of tissues. Computational simulations incorporating a simplified model of subcutaneous hemorrhage described in this work were used to evaluate this method. The dielectric properties data of tissues in the model of simulation is derived from the literature. The simulation results demonstrated the potential of this method to detect abnormal subepidermal tissues conveniently and expose them in the image accurately.
authors.affiliation: College of Science, National University of Defense Technology, Changsha, Hunan 410073, P.R. China.
authors.forename: Liang
authors.initials: L
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Complex Electromagnetic Environmental Effects on Electronics & Information System, National University of Defense Technology, Changsha, Hunan 410073, P.R. China.
authors.forename: Peiguo
authors.initials: P
authors.lastname: Liu
authors.affiliation: Faculty of Biomedical Engineering, Fourth Military Medical University, Xi'an, Shaanxi 710032, P.R. China.
authors.forename: Xiuzhen
authors.initials: X
authors.lastname: Dong
authors.affiliation: State Key Laboratory of Complex Electromagnetic Environmental Effects on Electronics & Information System, National University of Defense Technology, Changsha, Hunan 410073, P.R. China.
authors.forename: Dongming
authors.initials: D
authors.lastname: Zhou
authors.affiliation: Faculty of Biomedical Engineering, Fourth Military Medical University, Xi'an, Shaanxi 710032, P.R. China.
authors.forename: Xuetao
authors.initials: X
authors.lastname: Shi
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D058266:Dielectric Spectroscopy / Q000379:methods*; D006470:Hemorrhage / Q000175:diagnosis* / Q000503:physiopathology*; D006801:Humans; D008872:Microwaves; D008954:Models, Biological; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012867:Skin / Q000503:physiopathology*; D012871:Skin Diseases / Q000175:diagnosis* / Q000503:physiopathology*; D014054:Tomography / Q000379:methods
keywords: Coaxial probe; dielectric properties; scanning imaging; simulated annealing; subepidermal tissues