title: Outcome of total arch replacement with coronary artery bypass grafting.
abstract: OBJECTIVE
  There are few reports on the outcome of total arch replacement (TAR) with concomitant coronary artery bypass grafting (CABG); the present study was aimed at analysing outcomes after TAR with CABG at our institute.
  
  
  METHODS
  Between January 2002 and December 2012, 123 consecutive patients underwent elective TAR with or without CABG. The patients were divided into two groups: 46 who had concomitant CABG (Group T/C) and the rest, who had TAR only (Group T). TAR was performed under mild hypothermic circulatory arrest and selective antegrade cerebral perfusion (SACP) using a four-branched arch graft.
  
  
  RESULTS
  The number with a low ejection fraction (<50%) was higher in Group T/C, in which the additive and the logistic EuroSCORE were also higher. The mean number of coronary anastomoses was 1.6 ± 0.8 in Group T/C. The mean durations of surgery (P < 0.01), cardiopulmonary bypass (P < 0.01), cardiac ischaemia (P < 0.01) and SACP (P < 0.01) were significantly longer in Group T/C. The early graft patency of bypass grafts was 96.7%. Between Group T and Group T/C, there were no significant differences in the incidence of stroke (3.9 and 10.9%, P = 0.13), perioperative myocardial infarction (0 and 2.2%, P = 0.37) and in-hospital mortality (2.6 and 8.7%, P = 0.14). There was one case of 30-day mortality in each group. Preoperative haemodialysis, NYHA III/IV and operation time were multivariate predictors (P < 0.05) of in-hospital mortality.
  
  
  CONCLUSIONS
  Although concomitant CABG in TAR patients had higher operative risk, it can be safely performed with favourable outcomes.
authors.affiliation: Division of Cardiovascular Surgery, Shiga University of Medical Science, Otsu, Shiga, Japan ntaka@belle.shiga-med.ac.jp.
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Takashima
authors.affiliation: Division of Cardiovascular Surgery, Shiga University of Medical Science, Otsu, Shiga, Japan.
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Suzuki
authors.affiliation: Division of Cardiovascular Surgery, Shiga University of Medical Science, Otsu, Shiga, Japan.
authors.forename: Tohru
authors.initials: T
authors.lastname: Asai
authors.affiliation: Division of Cardiovascular Surgery, Shiga University of Medical Science, Otsu, Shiga, Japan.
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Nota
authors.affiliation: Division of Cardiovascular Surgery, Shiga University of Medical Science, Otsu, Shiga, Japan.
authors.forename: Hirohisa
authors.initials: H
authors.lastname: Ikegami
authors.affiliation: Division of Cardiovascular Surgery, Shiga University of Medical Science, Otsu, Shiga, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kinoshita
authors.affiliation: Division of Cardiovascular Surgery, Shiga University of Medical Science, Otsu, Shiga, Japan.
authors.forename: Susumu
authors.initials: S
authors.lastname: Fujino
authors.affiliation: Division of Cardiovascular Surgery, Shiga University of Medical Science, Otsu, Shiga, Japan.
authors.forename: Soh
authors.initials: S
authors.lastname: Hosoba
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects* / Q000401:mortality*; D001026:Coronary Artery Bypass / Q000009:adverse effects* / Q000401:mortality*; D003324:Coronary Artery Disease / Q000453:epidemiology / Q000601:surgery; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies; D016896:Treatment Outcome
keywords: Concomitant procedures; Coronary artery bypass grafting; Total arch replacement