title: Rapid access to benzoxaphospholes and their spiro analogues by a three-component coupling involving arynes, phosphines, and activated ketones.
abstract: An operationally simple multicomponent coupling involving in situ generated arynes from 2-(trimethylsilyl)aryl triflates, phosphines, and various acyclic and cyclic activated carbonyl compounds has been developed. The reaction proceeds via a formal [3 + 2] cycloaddition mode giving access to differently substituted (spiro)benzoxaphosphole derivatives in moderate to good yields. Mild reaction conditions, a broad scope, and the possibility of varying all the three-components are the notable features of the present reaction.
authors.affiliation: Organic Chemistry Division, ‡Centre for Materials Characterization, CSIR-National Chemical Laboratory (CSIR-NCL) , Dr. Homi Bhabha Road, Pune - 411008, India.
authors.forename: Anup
authors.initials: A
authors.lastname: Bhunia
authors.forename: Tony
authors.initials: T
authors.lastname: Roy
authors.forename: Rajesh G
authors.initials: RG
authors.lastname: Gonnade
authors.forename: Akkattu T
authors.initials: AT
authors.lastname: Biju