title: Successful treatment of Kimura's disease with leflunomide and methylprednisolone: a case report.
abstract: Kimura's disease (KD) is an uncommon, chronic inflammatory disease characterized by tumor-like lesions in the soft tissue and lymph nodes and increased peripheral blood eosinophil counts and serum immunoglobulin E (IgE). Prednisone is widely used to treat the disease. Here, we reported a 59-year-old KD patient failed to response to prednisone. Leflunomide combined with methylprednisolone (Medrol) were carried out to treat KD and encouraging outcome was obtained during the medication and 1 year follow up period.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, People's Republic of China.
authors.forename: Xiao-Rong
authors.initials: XR
authors.lastname: Ma
authors.affiliation: Department of Nursing, Huadong Hospital, Shanghai Fudan University Shanghai, People's Republic of China.
authors.forename: Shu-Jia
authors.initials: SJ
authors.lastname: Xin
authors.affiliation: Department of Plastic and Reconstructive Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, People's Republic of China.
authors.forename: Tian-Xiang
authors.initials: TX
authors.lastname: Ouyang
authors.affiliation: Department of Plastic and Reconstructive Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, People's Republic of China.
authors.forename: Yue-Ting
authors.initials: YT
authors.lastname: Ma
authors.affiliation: Department of Rheumatology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, People's Republic of China.
authors.forename: Wei-Ying
authors.initials: WY
authors.lastname: Chen
authors.affiliation: Department of Plastic and Reconstructive Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, People's Republic of China.
authors.forename: Meng-Ling
authors.initials: ML
authors.lastname: Chang
keywords: Kimura’s disease; effect; eosinophilia; leflunomide