title: Synthesis of substituted azafluorenones from dihalogeno diaryl ketones by palladium-catalyzed auto-tandem processes.
abstract: Substituted azafluorenones were synthesized from different dihalogeno diaryl ketones under palladium catalysis by combining either Suzuki or Heck coupling with direct cyclizing arylation. Conditions were identified to allow both auto-tandem processes to proceed successfully from 3-(bromobenzoyl)- or 3-benzoyl-4-bromo-2-chloropyridines, as well as 4-benzoyl-2,3- and 4-benzoyl-2,5-dichloropyridines.
authors.affiliation: Chimie et Photonique Moléculaires, Institut des Sciences Chimiques de Rennes, UMR 6226, Université de Rennes 1 - CNRS, Bâtiment 10A, Case 1003, Campus de Beaulieu, CS74205, 35042 Rennes Cedex, France. floris.chevallier@univ-rennes1.fr florence.mongin@univ-rennes1.fr.
authors.forename: Nada
authors.initials: N
authors.lastname: Marquise
authors.forename: Vincent
authors.initials: V
authors.lastname: Dorcet
authors.forename: Floris
authors.initials: F
authors.lastname: Chevallier
authors.forename: Florence
authors.initials: F
authors.lastname: Mongin
mesh_terms: D001372:Aza Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D005449:Fluorenes / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: D001372:Aza Compounds; D005449:Fluorenes; D007659:Ketones; D010165:Palladium