title: Iodine-mediated oxidative annulation for one-pot synthesis of pyrazines and quinoxalines using a multipathway coupled domino strategy.
abstract: An efficient iodine-mediated oxidative annulation of aryl acetylenes-arylethenes-aromatic ketones with 1,2-diamines for the synthesis of pyrazines and regioselective synthesis of quinoxalines is presented. A multipathway coupled domino approach has been developed for the one-pot synthesis of 1,4-diazines with high functional group compatibility.
authors.affiliation: Pharmaceutics Division, CSIR-Central Drug Research Institute, Lucknow-226 031, India.
authors.forename: K K Durga Rao
authors.initials: KK
authors.lastname: Viswanadham
authors.forename: Muktapuram
authors.initials: M
authors.lastname: Prathap Reddy
authors.forename: Pochampalli
authors.initials: P
authors.lastname: Sathyanarayana
authors.forename: Owk
authors.initials: O
authors.lastname: Ravi
authors.forename: Ruchir
authors.initials: R
authors.lastname: Kant
authors.forename: Surendar Reddy
authors.initials: SR
authors.lastname: Bathula
mesh_terms: D003500:Cyclization; D003959:Diamines / Q000737:chemistry; D005030:Ethylenes / Q000737:chemistry; D007455:Iodine / Q000737:chemistry*; D010084:Oxidation-Reduction; D011719:Pyrazines / Q000138:chemical synthesis / Q000737:chemistry*; D011810:Quinoxalines / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D003959:Diamines; D005030:Ethylenes; D011719:Pyrazines; D011810:Quinoxalines; D007455:Iodine