title: Tailoring Mg(x)Mn(1-x)Fe(2)O(4) superparamagnetic nanoferrites for magnetic fluid hyperthermia applications.
abstract: A superparamagnetic nanoferrite (SPNF) with high magnetic moment, AC magnetically induced heating (AC-heating) capacity, and good biocompatibility is the most vital part of magnetic fluid hyperthermia for utilizing it in the clinics. Herein, we precisely tune magnetic properties and AC-heating characteristics of MgxMn1-xFe2O4 SPNF via chemically controlling the cations' concentration and distribution to develop a tailored MgxMn1-xFe2O4 SPNF as a potential magnetic fluid hyperthermia agent. The magnetic and AC-heating characteristics of the tailored MgxMn1-xFe2O4 SPNF are strongly dependent on the Mg/Mn cations' concentration and distribution, and Mg0.285Mn0.715Fe2O4 SPNF exhibits the highest saturation magnetization and AC-heating capacity as well as high biocompatibility.
authors.affiliation: Biomedical Research Institute, Korea Institute of Science and Technology (KIST) , Seoul 136-791, Republic of Korea.
authors.forename: Minhong
authors.initials: M
authors.lastname: Jeun
authors.forename: Sungwook
authors.initials: S
authors.lastname: Park
authors.forename: Gun Hyuk
authors.initials: GH
authors.lastname: Jang
authors.forename: Kwan Hyi
authors.initials: KH
authors.lastname: Lee
mesh_terms: D002412:Cations; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D004560:Electricity; D005290:Ferric Compounds / Q000494:pharmacology*; D006801:Humans; D006979:Hyperthermia, Induced; D008055:Lipids / Q000737:chemistry; D017616:Magnesium Compounds / Q000494:pharmacology*; D060328:Magnetic Phenomena; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D017895:Manganese Compounds / Q000494:pharmacology*; D010316:Particle Size; D013696:Temperature; D014961:X-Ray Diffraction
chemical_list: D002412:Cations; D005290:Ferric Compounds; D008055:Lipids; D017616:Magnesium Compounds; D058185:Magnetite Nanoparticles; D017895:Manganese Compounds; C551151:manganese ferrite; C016546:magnesium ferrite
keywords: MgMnFe2O4; magnetic hyperthermia; nanoferrite; nanofluid; superparamagnetic particle