title: Visible-light-mediated 1,2-acyl migration: the reaction of secondary enamino ketones with singlet oxygen.
abstract: Secondary enaminones were oxidized by photochemically generated singlet oxygen, followed by nucleophilic addition of alcohol and an unexpected 1,2-acyl migration to afford quaternary amino acid derivatives. An ene-type reaction pathway is proposed. It is distinctively different from the typical [2+2] addition of singlet oxygen to a C=C bond pathway.
authors.affiliation: Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering, and Materials Science, Soochow University, 199 RenAi Road, Suzhou, Jiangsu 215123 (China).
authors.forename: Weigang
authors.initials: W
authors.lastname: Fan
authors.forename: Pixu
authors.initials: P
authors.lastname: Li
keywords: ene reaction; photochemistry; reaction mechanisms; ruthenium; singlet oxygen