title: [Immunometabolism of exercise and sedentary lifestyle].
abstract: Sedentary lifestyle leads to the accumulation of visceral fat. This is accompanied by the infiltration of immune cells with pro-inflammatory characteristics in adipose tissue, causing an increased release of cytokines and generating a low-grade inflammatory state. It has been associated with the development of insulin resistance, atherosclerosis, neurodegeneration, and development of tumors. Exercise can be used as a treatment to improve symptoms of many of these conditions because it promotes an anti-inflammatory effect. In this review we analyze the pro-inflammatory factors present in obesity and the induction of antiinflammatory factors that occur with exercise.
authors.forename: Mario Adán
authors.initials: MA
authors.lastname: Moreno-Eutimio
authors.forename: Gustavo
authors.initials: G
authors.lastname: Acosta-Altamirano
mesh_terms: D054392:Adipokines / Q000378:metabolism; D050197:Atherosclerosis / Q000209:etiology / Q000276:immunology / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000209:etiology / Q000276:immunology / Q000378:metabolism; D016207:Cytokines / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology / Q000276:immunology / Q000378:metabolism; D004837:Epinephrine / Q000378:metabolism; D015444:Exercise / Q000502:physiology; D005081:Exercise Therapy; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism; D007249:Inflammation / Q000209:etiology* / Q000276:immunology / Q000378:metabolism / Q000517:prevention & control; D007333:Insulin Resistance; D015850:Interleukin-6 / Q000378:metabolism; D050152:Intra-Abdominal Fat / Q000378:metabolism; D008264:Macrophages / Q000378:metabolism; D009119:Muscle Contraction; D009369:Neoplasms / Q000209:etiology / Q000276:immunology / Q000378:metabolism; D009410:Nerve Degeneration / Q000209:etiology / Q000276:immunology / Q000378:metabolism; D009765:Obesity / Q000150:complications* / Q000276:immunology / Q000378:metabolism; D018384:Oxidative Stress; D057185:Sedentary Behavior; D050378:T-Lymphocytes, Regulatory / Q000276:immunology; D051193:Toll-Like Receptors / Q000378:metabolism; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
chemical_list: D054392:Adipokines; D016207:Cytokines; C508600:IL6 protein, human; D015850:Interleukin-6; D051193:Toll-Like Receptors; D014409:Tumor Necrosis Factor-alpha; D006854:Hydrocortisone; D004837:Epinephrine
keywords: Low-grade inflammation; anti-inflammatory cytokines; citocinas anti-inflamatorias; citocinas proinflamatorias.; ejercicio físico; exercise; inflamación de bajo grado; obesidad; obesity; pro-inflammatory cytokines