title: Antigonon leptopus: a potent biological source for extermination of fish bacterial pathogens Providencia and Aeromonas.
abstract: This study pertains to the phytochemical components and the biological properties of the weed, Antigonon leptopus Hook. & Arn. (AUT/PUS/064). Phytochemical screening of methanolic leaf extract of A. leptopus revealed the presence of saponin, phenolic compounds, tannins, flavonoids, alkaloids, fixed oils and amino acids. Accordingly, 12 phytochemical components were analysed and characterised by GC-MS. Antibacterial activity was evaluated against fish and clinical pathogens. Fish pathogens, Providencia vermicola (MTCC 5578) and Aeromonas hydrophila (MTCC 646) were more sensitive to the methanolic leaf extract than clinical pathogens. A useful information was obtained from the phytochemistry of A. leptopus leaves, which would pave way to further applications to treat fish diseases and for utility in the pharmaceutical field.
authors.affiliation: a Department of Biotechnology, Periyar University , Periyar Palkalai Nagar, Salem 636 011 , Tamil Nadu , India.
authors.forename: Govindasamy
authors.initials: G
authors.lastname: Balasubramani
authors.forename: Paramasivam
authors.initials: P
authors.lastname: Deepak
authors.forename: Rajamani
authors.initials: R
authors.lastname: Sowmiya
authors.forename: Rajendiran
authors.initials: R
authors.lastname: Ramkumar
authors.forename: Pachiappan
authors.initials: P
authors.lastname: Perumal
mesh_terms: D016980:Aeromonas hydrophila / Q000187:drug effects*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification; D005399:Fishes / Q000382:microbiology; D008401:Gas Chromatography-Mass Spectrometry; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D019664:Polygonaceae / Q000737:chemistry*; D011532:Providencia / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts
keywords: Aeromonas hydrophila; Antigonon leptopus; GC–MS; Providencia vermicola; clinical pathogens