title: Primary enteric-type mucinous adenocarcinoma of the urethra in a patient with ulcerative colitis.
abstract: Primary carcinoma of the male urethra accounts for less than 1% of malignancies in men. Mucinous adenocarcinoma of the urethra is extremely rare, and its biologic behavior is poorly understood. We present herein a rare case of mucinous urethral adenocarcinoma in a male patient with longstanding ulcerative colitis and multiple sclerosis. The patient presented with a voluminous pelvic mass; core biopsy of the lesion demonstrated a mucus-producing adenocarcinoma. Given the patient's history of subtotal colectomy, preoperative diagnosis was oriented towards a rectal stump adenocarcinoma. The patient underwent a pelvic exenteration: surprisingly, histology marked the prostatic urethra as the primary lesion site.
authors.affiliation: 2nd Propedeutic Department of Surgery, Athens University Medical School, Laikon Hospital Athens, Greece.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Dimitroulis
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Patsouras
authors.forename: Athanasios
authors.initials: A
authors.lastname: Katsargyris
authors.forename: Petros
authors.initials: P
authors.lastname: Charalampoudis
authors.forename: Ioannis
authors.initials: I
authors.lastname: Anastasiou
authors.forename: Gregory
authors.initials: G
authors.lastname: Kouraklis
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000473:pathology* / Q000601:surgery; D000328:Adult; D003093:Colitis, Ulcerative / Q000150:complications*; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000150:complications; D014523:Urethral Neoplasms / Q000473:pathology* / Q000601:surgery
keywords: Adenocarcinoma; Mucinous; Ulcerative colitis; Urethra