title: Fabrication of copper nanoparticles decorated multiwalled carbon nanotubes as a high performance electrochemical sensor for the detection of neotame.
abstract: A highly sensitive and novel electrochemical sensor for the detection of neotame using differential pulse voltammetry with a modified glassy carbon electrode is presented. The method was further customized by the fabrication of the electrode surface with copper nanoparticles-ammonium piperidine dithiocarbamate-mutiwalled carbon nanotubes assimilated with β-cyclodextrin. The multiwalled carbon nanotubes assimilated with β-cyclodextrin/glassy carbon electrode exhibited catalytic activity towards the oxidation of neotame at a potential of 1.3 V at pH 3.0. The transmission electron microscopy, thermogravimetric analysis, frontier transform infrared spectroscopy and cyclic voltammetry were employed to characterize the electrochemical sensor. The sensitivity and detection limits of the electrode increased two-fold in contrast to the β-CD-MWCNTs/GCE sensor. The developed method was successfully applied for the determination of neotame in food samples, with results similar to those achieved by our modified capillary electrophoresis method with a 96% confidence level.
authors.affiliation: Department of Chemistry, Durban University of Technology, P.O. Box 1334, Durban 4000, South Africa.
authors.forename: Ayyappa
authors.initials: A
authors.lastname: Bathinapatla
authors.affiliation: Department of Chemistry, Durban University of Technology, P.O. Box 1334, Durban 4000, South Africa. Electronic address: ksuvardhan@gmail.com.
authors.forename: Suvardhan
authors.initials: S
authors.lastname: Kanchi
authors.affiliation: School of Chemistry and Physics, University of KwaZulu Natal, Westville, Private Bag X54001, Durban 4000, South Africa.
authors.forename: Parvesh
authors.initials: P
authors.lastname: Singh
authors.affiliation: Department of Chemistry, Durban University of Technology, P.O. Box 1334, Durban 4000, South Africa.
authors.forename: Myalowenkosi I
authors.initials: MI
authors.lastname: Sabela
authors.affiliation: Department of Chemistry, Durban University of Technology, P.O. Box 1334, Durban 4000, South Africa. Electronic address: bisettyk@dut.ac.za.
authors.forename: Krishna
authors.initials: K
authors.lastname: Bisetty
mesh_terms: D003217:Conductometry / Q000295:instrumentation*; D003300:Copper / Q000737:chemistry*; D004151:Dipeptides / Q000032:analysis*; D004566:Electrodes; D005503:Food Additives / Q000032:analysis; D005504:Food Analysis / Q000295:instrumentation*; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013549:Sweetening Agents / Q000032:analysis
chemical_list: D004151:Dipeptides; D005503:Food Additives; D037742:Nanotubes, Carbon; D013549:Sweetening Agents; D003300:Copper; C404525:neotame
keywords: Cyclic voltammetry; Differential pulse voltammetry; Electrochemical sensor; Neotame