title: Conjunctival Pigmentation Following Minocycline Therapy.
abstract: Minocycline is a tetracycline antibiotic commonly used to treat acne and rosacea. Although pigmentation of the skin, nails, teeth, oral mucosa, and sclera is a well-recognized adverse outcome associated with minocycline, ocular pigmentation may be missed on routine examination. The authors present a case of a 43-year-old white woman who demonstrated bilateral pigmented palpebral conjunctival cysts after 12 months of minocycline therapy for cystic acne. To date, only 5 cases of minocycline-induced conjunctival pigmentation have been reported. After drug discontinuation, the patient's examination remained stable and no new ocular lesions were noted.
authors.affiliation: *Department of Ophthalmology, Louisiana State University Health Sciences Center; †Department of Ophthalmology, Ochsner Clinic Foundation, New Orleans, Louisiana, U.S.A.; and ‡Charlotte Eye Ear Nose & Throat Associates, Charlotte, North Carolina, U.S.A.
authors.forename: Tanya T
authors.initials: TT
authors.lastname: Khan
authors.forename: Usha P
authors.initials: UP
authors.lastname: Reddy
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D001706:Biopsy; D003228:Conjunctiva / Q000000981:diagnostic imaging*; D003229:Conjunctival Diseases / Q000139:chemically induced* / Q000175:diagnosis; D005260:Female; D006801:Humans; D008911:Minocycline / Q000009:adverse effects*; D010859:Pigmentation Disorders / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D000900:Anti-Bacterial Agents; D008911:Minocycline