title: Adult sickle cell disease epidemiology and the potential role of a multidisciplinary comprehensive care center in a city with low prevalence.
abstract: The aim of this study was to determine the characteristics of the sickle cell disease population in a city of low prevalence and compare them to those reported in the literature. We performed a retrospective cross-sectional study of all sickle cell disease patients seen in the Calgary Health Region, Calgary, Alberta, Canada from 2006 to 2010. Data on clinical endpoints including emergency department (ED) visits, hospital admissions, transfusions, as well as laboratory parameters were collected. A total of 37 adult sickle cell disease patients were identified. Over 5 years, they were represented by a total of 49.2 ED presentations/year, 29.2 (59.0%) of these requiring admission. Eighty-three percent of these presentations were for acute pain episodes. We concluded that the number of ED visits, hospital admissions and several other parameters in our cohort were similar to those in other centers of higher prevalence. This suggests that guidelines representing regions of high prevalence may be applicable to smaller centers, where patients experience similar clinical outcomes.
authors.affiliation: Division of Hematology, McGill University , Montreal, Québec , Canada .
authors.forename: Andrew
authors.initials: A
authors.lastname: Binding
authors.forename: Karen
authors.initials: K
authors.lastname: Valentine
authors.forename: Man-Chiu
authors.initials: MC
authors.lastname: Poon
authors.forename: Farzana A
authors.initials: FA
authors.lastname: Sayani
mesh_terms: D059787:Acute Pain / Q000209:etiology / Q000517:prevention & control; D000328:Adult; D000416:Alberta / Q000453:epidemiology; D000755:Anemia, Sickle Cell / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D015331:Cohort Studies; D003191:Comprehensive Health Care; D003430:Cross-Sectional Studies; D004636:Emergency Service, Hospital; D005260:Female; D006405:Hematology; D006786:Hospitals, Urban; D006801:Humans; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D010044:Outpatient Clinics, Hospital; D010819:Physician's Role; D015995:Prevalence; D012189:Retrospective Studies; D014504:Urban Health; D000078329:Workforce; D055815:Young Adult
keywords: Adult; comprehensive care; epidemiology; low prevalence; multidisciplinary; sickle cell disease