title: Gastric cancer following bariatric surgery: a review.
abstract: BACKGROUND
  Bariatric procedures can induce a massive weight loss that lasts for >15 years after surgery; in addition, they achieve important metabolic effects including diabetes resolution in the majority of morbidly obese patients. However, some bariatric interventions may cause gastroesophageal reflux disease and other serious complications. The aim of our study is to evaluate the risk of cancer after bariatric surgery.
  
  
  METHODS
  We conducted a review of the literature about the cases of gastric cancer arising after any bariatric procedure, including a case of adenocarcinoma incidentally discovered by the authors 6 months after laparoscopic adjustable gastric banding.
  
  
  RESULTS
  Globally, 17 case reports describing 18 patients were retrieved, including the case study by the authors. The diagnosis of tumor was at a mean of 8.6 years after bariatric surgery, 9.3 years after RYGB, and 8.1 years after restrictive procedures. The adenocarcinoma represented most cases (15 patients, 83%). In the patients with RYGB, the adenocarcinoma was localized in the excluded stomach in 5 patients (83%) and in the pouch in 1 patient (17%). After a restrictive procedure, the cancer was localized in the pouch in 5 patients (62.5%), in the pylorus in 2 patients (25%), and in lesser curvature only in 1 patient (12.5%).
  
  
  CONCLUSIONS
  There is a lack of evidence about a connection between the late occurrence of gastric adenocarcinoma and the bariatric surgery. For this reason, although the preoperative upper endoscopy is still mandatory, there is no need for a regular endoscopic evaluation of patients after surgery.
authors.affiliation: *Department of Surgery, University Magna Graecia, Catanzaro †Department of Medicine and Surgery, University of Salerno, Salerno ‡Department of Internal Medicine and Surgery, University "Federico II" of Naples, Naples §Department of Medico-Surgical Sciences and Biotechnologies, Division of General Surgery, "La Sapienza" University of Rome, ICOT, Latina, 00185, Italy.
authors.forename: Giulio
authors.initials: G
authors.lastname: Orlando
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Pilone
authors.forename: Antonio
authors.initials: A
authors.lastname: Vitiello
authors.forename: Rita
authors.initials: R
authors.lastname: Gervasi
authors.forename: Maria A
authors.initials: MA
authors.lastname: Lerose
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Silecchia
authors.forename: Alessandro
authors.initials: A
authors.lastname: Puzziello
mesh_terms: D000230:Adenocarcinoma / Q000209:etiology; D000328:Adult; D000368:Aged; D050110:Bariatric Surgery / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011708:Pylorus; D013274:Stomach Neoplasms / Q000209:etiology*; D013997:Time Factors