title: Association between exposure to hepatitis B virus and chronic kidney disease in China.
abstract: OBJECTIVE
  Hospital-based, cross-sectional study to determine whether exposure to hepatitis B virus (HBV) has an independent effect on the risk of developing chronic kidney disease (CKD).
  
  
  METHODS
  Han Chinese adults undergoing routine physical examinations were recruited. Blood was tested for the presence of hepatitis C virus (HCV) antibodies, HBV surface antigen, and antibodies against HBV core antigen and hepatitis B surface antigen (HBsAg). CKD was defined as estimated glomerular filtration rate (eGFR) <60 ml/min per 1.73 m(2) or presence of albuminuria.
  
  
  RESULTS
  The prevalence of HBV exposure was 42.1% (6,418/15,259 participants). There were no significant associations between HBV or HCV status and CKD, low eGFR or albuminuria.
  
  
  CONCLUSIONS
  There was no association between exposure to HBV and the risk of developing CKD in this Chinese study population.
authors.affiliation: International Medical Centre, Chinese PLA General Hospital, Beijing, China qiangzeng123@yeah.net.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Zeng
authors.affiliation: International Medical Centre, Chinese PLA General Hospital, Beijing, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Gong
authors.affiliation: International Medical Centre, Chinese PLA General Hospital, Beijing, China.
authors.forename: Shengyong
authors.initials: S
authors.lastname: Dong
authors.affiliation: International Medical Centre, Chinese PLA General Hospital, Beijing, China.
authors.forename: Hang
authors.initials: H
authors.lastname: Xiang
authors.affiliation: International Medical Centre, Chinese PLA General Hospital, Beijing, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000419:Albuminuria / Q000175:diagnosis / Q000453:epidemiology; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006509:Hepatitis B / Q000097:blood / Q000453:epidemiology / Q000821:virology*; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006515:Hepatitis B virus / Q000302:isolation & purification*; D018937:Hepatitis C Antibodies / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011379:Prognosis; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology / Q000821:virology*; D012307:Risk Factors; D055815:Young Adult
chemical_list: D006514:Hepatitis B Surface Antigens; D018937:Hepatitis C Antibodies
keywords: CKD; HCV; Past exposure to HBV; chronic HBV carrier