title: Renal abscess caused by Brucella.
abstract: Involvement of the renal parenchyma in the acute phase of brucellosis is very rare. Only two cases of renal brucelloma have been reported in the English language literature to date. We report a case of renal abscess caused by Brucella in the acute phase. A 45-year-old Chinese man presented with a high fever, urine occult blood, and a low density lesion in the right kidney. Ultrasound-guided aspiration was done. Brucella melitensis was isolated from both blood and puncture fluid culture. Minocycline combined with moxifloxacin was prescribed for 4 months. The infection relapsed at 6 months after discontinuation. Minocycline combined with rifampin was administered for another 2 months. The brucellosis had not relapsed at more than 20 months later. It is possible to cure renal brucelloma with antibiotics and ultrasound-guided aspiration. Treatment should not be discontinued until the abscess has disappeared and two consecutive blood cultures taken 1 month apart are negative.
authors.affiliation: Department of Infectious Diseases, Peking University First Hospital, 8 Xishiku Street, Xicheng District, Beijing, 100034, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Li
authors.affiliation: Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing Key Laboratory of Emerging Infectious Diseases, Beijing, China.
authors.forename: Yaru
authors.initials: Y
authors.lastname: Li
authors.affiliation: Department of Infectious Diseases, Peking University First Hospital, 8 Xishiku Street, Xicheng District, Beijing, 100034, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Infectious Diseases, Peking University First Hospital, 8 Xishiku Street, Xicheng District, Beijing, 100034, China.
authors.forename: Na
authors.initials: N
authors.lastname: Huo
authors.affiliation: Department of Infectious Diseases, Peking University First Hospital, 8 Xishiku Street, Xicheng District, Beijing, 100034, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Wan
authors.affiliation: Department of Infectious Diseases, Peking University First Hospital, 8 Xishiku Street, Xicheng District, Beijing, 100034, China.
authors.forename: Xiaohong
authors.initials: X
authors.lastname: Lin
authors.affiliation: Department of Infectious Diseases, Peking University First Hospital, 8 Xishiku Street, Xicheng District, Beijing, 100034, China.
authors.forename: Gengshan
authors.initials: G
authors.lastname: Tian
authors.affiliation: Department of Radiology, Peking University First Hospital, Beijing, China.
authors.forename: Xuedong
authors.initials: X
authors.lastname: Yang
authors.affiliation: Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing Key Laboratory of Emerging Infectious Diseases, Beijing, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Cheng
authors.affiliation: Department of Infectious Diseases, Peking University First Hospital, 8 Xishiku Street, Xicheng District, Beijing, 100034, China.
authors.forename: Guiqiang
authors.initials: G
authors.lastname: Wang
authors.affiliation: Department of Infectious Diseases, Peking University First Hospital, 8 Xishiku Street, Xicheng District, Beijing, 100034, China. Electronic address: minmin2001@gmail.com.
authors.forename: Hong
authors.initials: H
authors.lastname: Zhao
mesh_terms: D000038:Abscess / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017347:Brucella melitensis / Q000302:isolation & purification; D002006:Brucellosis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D004359:Drug Therapy, Combination; D024841:Fluoroquinolones / Q000627:therapeutic use; D006801:Humans; D007674:Kidney Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D008911:Minocycline / Q000627:therapeutic use; D000077266:Moxifloxacin; D012293:Rifampin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D008911:Minocycline; D000077266:Moxifloxacin; D012293:Rifampin
keywords: Brucella melitensis; Brucellosis; Renal brucelloma