title: Absence of HTLV-1/2 infection and dermatological diseases in Manaus, State of Amazonas, Brazil.
abstract: BACKGROUND
  The prevalence of human T-cell lymphotropic virus types 1 and 2 (HTLV-1/2) infection is heterogeneous across different populations. We tested the hypothesis that HTLV-1/2 infection occurs more often in dermatological patients.
  
  
  METHODS
  A total of 1,091 patients from a tropical dermatology clinic were tested for HTLV-1/2. In parallel, 6865 first-time blood donors from the same geographic area were screened for HTLV-1/2; HTLV-1/2 positive blood donors underwent dermatological examinations.
  
  
  RESULTS
  The prevalence of HTLV-1/2 in first-time blood donors was 0.14%. No co-occurrence of HTLV-1/2 infection and dermatological conditions was observed.
  
  
  CONCLUSIONS
  Our results challenge the hypothesis that HTLV-1/2 infection occurs more often in dermatological patients.
authors.affiliation: Departamento de Ensino e Pesquisa, Hematologia, Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas, Manaus, AM, Brazil.
authors.forename: Leny Nascimento da Motta
authors.initials: LN
authors.lastname: Passos
authors.affiliation: Departamento de Ensino e Pesquisa, Hematologia, Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas, Manaus, AM, Brazil.
authors.forename: Márcia Poinho Encarnação de
authors.initials: MP
authors.lastname: Moraes
authors.affiliation: Departamento de Imunologia Básica e Epidemiologia Básica, Faculdade Metropolitana da Amazônia, Manaus, AM, Brazil.
authors.forename: Bruna
authors.initials: B
authors.lastname: Tamegão-Lopes
authors.affiliation: Departamento de Laboratórios de Biologia Celular e Molecular do Hemocentro do PRA, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, PA, Brazil.
authors.forename: José Alexandre Rodrigues de
authors.initials: JA
authors.lastname: Lemos
authors.affiliation: Serviço de Imunologia, Universidade Federal da Bahia, Salvador, BA, Brasil.
authors.forename: Paulo Roberto de Lima
authors.initials: PR
authors.lastname: Machado
authors.affiliation: Programa de Pós-Graduação em Ciências da Saúde, Centro de Ciências Biológicas e da Saúde de Curitiba, Pontifícia Universidade Católica do Paraná, Curitiba, PR, Brasil.
authors.forename: Marcelo Távora
authors.initials: MT
authors.lastname: Mira
authors.affiliation: Departamento de Dermatologia Tropical, Fundação de Medicina Tropical Heitor Dourado do Amazonas. Clínica de Dermatologia Talhari, Universidade Nilton Lins do Amazonas, Manaus, AM, Brazil.
authors.forename: Sinésio
authors.initials: S
authors.lastname: Talhari
mesh_terms: D000328:Adult; D001782:Blood Donors / Q000706:statistics & numerical data*; D015153:Blotting, Western; D001938:Brazil / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D015481:HTLV-I Antibodies / Q000097:blood; D015490:HTLV-I Infections / Q000175:diagnosis / Q000453:epidemiology*; D015482:HTLV-II Antibodies / Q000097:blood; D015491:HTLV-II Infections / Q000175:diagnosis / Q000453:epidemiology*; D015368:Human T-lymphotropic virus 1 / Q000276:immunology; D015367:Human T-lymphotropic virus 2 / Q000276:immunology; D006801:Humans; D008297:Male; D015995:Prevalence; D017193:Skin Diseases, Viral / Q000175:diagnosis / Q000453:epidemiology*
chemical_list: D015481:HTLV-I Antibodies; D015482:HTLV-II Antibodies