title: Can fentanyl transdermal patches prevent the cutaneous hyperpigmentation related to radiotherapy in patients with cancer?
abstract: Dermatologic adverse effects related to radiotherapy are one of the most important cosmetic problems and affect the quality of life in patients with cancer. In a male patient with non-small cell lung cancer who received palliative radiotherapy, the hyperpigmentation related to radiotherapy was examined two months later except for fentanyl transdermal patch area. The inhibitory effect of fentanyl on cell cycle may prevent hyperpigmentation related to radiotherapy.
authors.affiliation: Department of Medical Oncology, Akdeniz University School of Medicine, Antalya, Turkey doktorhasanmutlu@gmail.com.
authors.forename: Hasan
authors.initials: H
authors.lastname: Mutlu
mesh_terms: D000701:Analgesics, Opioid / Q000008:administration & dosage*; D002289:Carcinoma, Non-Small-Cell Lung / Q000532:radiotherapy*; D005283:Fentanyl / Q000008:administration & dosage*; D006801:Humans; D017495:Hyperpigmentation / Q000209:etiology / Q000517:prevention & control*; D008175:Lung Neoplasms / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D011832:Radiation Injuries / Q000209:etiology / Q000517:prevention & control*; D057968:Transdermal Patch
chemical_list: D000701:Analgesics, Opioid; D005283:Fentanyl
keywords: Cancer; hyperpigmentation; melanosis; radiation therapy