title: The effect of topical 1% cyclopentolate on IOLMaster biometry.
abstract: OBJECTIVE
  To investigate the effects of topical cyclopentolate on ocular biometry parameters in healthy young adults.
  
  
  METHODS
  Ocular biometry measurements were performed twice with 45-minute intervals by use of the IOLMaster. Effects of topical application of 1% cyclopentolate were examined in 25 eyes from 25 young adults (group 1) before and after its application. As a control (cyclopentolate-free, group 2), 30 eyes from 30 age- and sex-matched healthy subjects were evaluated within the same period.
  
  
  RESULTS
  There was no difference between the groups with respect to mean (±SD) ages (group 1: 23 [±3.19] years [range, 18 to 28 years] vs. group 2: 22.6 [±2.7] years [range, 18 to 28 years], p = 0.616). In group 1, the anterior chamber depth and horizontal iris width (white-to-white distance) measurements between the two sessions were significantly different, whereas the axial length was not. In group 2, none of these parameters were different between the two sessions.
  
  
  CONCLUSIONS
  Topical application of 1% cyclopentolate caused an increase in the anterior chamber depth and white-to-white distance values without any significant effect on axial length measurement. It is necessary to consider these effects on measurements taken with an IOLMaster in young adults in whom 1% cyclopentolate has been applied.
authors.affiliation: *MD Department of Ophthalmology, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey (CA); Department of Ophthalmology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey (AT, MK); and Department of Ophthalmology, Gulhane Military Medical Academy, Ankara, Turkey (OMC).
authors.forename: Ceyhun
authors.initials: C
authors.lastname: Arici
authors.forename: Adem
authors.initials: A
authors.lastname: Turk
authors.forename: Osman Melih
authors.initials: OM
authors.lastname: Ceylan
authors.forename: Mehmet
authors.initials: M
authors.lastname: Kola
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000867:Anterior Chamber / Q000187:drug effects*; D058452:Axial Length, Eye / Q000187:drug effects; D001699:Biometry; D003519:Cyclopentolate / Q000008:administration & dosage*; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D007368:Interferometry; D007498:Iris / Q000187:drug effects*; D008027:Light; D008297:Male; D009184:Mydriatics / Q000008:administration & dosage*; D009883:Ophthalmic Solutions; D011446:Prospective Studies; D055815:Young Adult
chemical_list: D009184:Mydriatics; D009883:Ophthalmic Solutions; D003519:Cyclopentolate