title: Diffuse cutaneous allergic reaction to Dermabond.
abstract: Wound closure with 2-octyl cyanoacrylate (Dermabond; Ethicon, Somerville, New Jersey USA) has recently increased in popularity across a wide spectrum of physicians ranging from surgeons to emergency medicine practitioners. Generally, very few complications are associated with Dermabond and are usually related to application techniques. Uncommonly, patients present with allergic reactions to the adhesive compounds; these allergies are often misdiagnosed as cellulitis or another infectious process, and are incorrectly treated. This report describes a rare case of a diffuse cutaneous allergic reaction to Dermabond following its use to close a surgical incision, its prompt identification, and treatment after presentation to an emergency department.
authors.affiliation: 1Division of Plastic Surgery,Brigham and Women's Hospital,Harvard Medical School,Boston,MassachusettsUSA.
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Ricci
authors.affiliation: 2Department of Physical Medicine and Rehabilitation,Thomas Jefferson University Hospital,Philadelphia,PennsylvaniaUSA.
authors.forename: Nirav N
authors.initials: NN
authors.lastname: Parekh
authors.affiliation: 3Department of Radiology,Brigham and Women's Hospital,Harvard Medical School,Boston,MassachusettsUSA.
authors.forename: Naman S
authors.initials: NS
authors.lastname: Desai
mesh_terms: D019928:Breast Implantation / Q000009:adverse effects; D001943:Breast Neoplasms / Q000601:surgery; D003487:Cyanoacrylates / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis* / Q000209:etiology; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis* / Q000209:etiology; D014014:Tissue Adhesives / Q000009:adverse effects*
chemical_list: D003487:Cyanoacrylates; D014014:Tissue Adhesives; C100832:octyl 2-cyanoacrylate