title: A case of mucoepidermoid carcinoma located in the left forearm of a middle-aged pregnant woman.
abstract: In this article, we described a mucoepidermoid carcinoma (MEC) located in the left forearm of a 39-year-old pregnant woman. Here, the patient had a superficial tip size apophysis nearly 3 years, which begin to sustained growth after pregnant in 2012, and stopped growth after childbirth. MEC is a rare malignant tumor. Previously reports showed it mainly arise from the salivary, bronchial, thyroid, breast, lacrimal gland and conjunctiva. Here, we reported a case of MEC arising from the forearm gland for the first time. Histological finding showed a cystic and solid tumor in fibrous tissue below the squamous epithelium, and some columnar or cuboidal mucous cells covering on the epidermal cells or mixed with epidermal cells included in the tumor tissues. Also, Focal hyperplasia epidermal cells with round or oval nucleus in center were distributed in small pieces but no keratosis. The tumor tissues were immunopositive for CEA, P63, ki-67 (10%), CK7 and CK5/6, and immunonegative for CK20 and GCDFP-15. This case is a low-grade MEC and the patient's postoperative recovery is smooth.
authors.affiliation: Department of Pathology, Taiping People's Hospital of Dongguan, Dongguan Hospital Affiliated to Medical College of Jinan University Dongguan 523905, China.
authors.forename: Yan-Fang
authors.initials: YF
authors.lastname: Liang
authors.affiliation: Department of Endocrinology, Taiping People's Hospital of Dongguan, Dongguan Hospital Affiliated to Medical College of Jinan University Dongguan 523905, China.
authors.forename: Xiao-Yue
authors.initials: XY
authors.lastname: Lin
authors.affiliation: Department of Pathology, Taiping People's Hospital of Dongguan, Dongguan Hospital Affiliated to Medical College of Jinan University Dongguan 523905, China.
authors.forename: Jian-Bo
authors.initials: JB
authors.lastname: Ruan
authors.affiliation: Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Guandong Medical College Dongguan 523808, China.
authors.forename: Jin-Cheng
authors.initials: JC
authors.lastname: Zeng
authors.affiliation: Department of Pathology, Taiping People's Hospital of Dongguan, Dongguan Hospital Affiliated to Medical College of Jinan University Dongguan 523905, China.
authors.forename: Dong-Ping
authors.initials: DP
authors.lastname: Kang
authors.affiliation: Department of Pathology, Taiping People's Hospital of Dongguan, Dongguan Hospital Affiliated to Medical College of Jinan University Dongguan 523905, China.
authors.forename: Ling-Mei
authors.initials: LM
authors.lastname: Wang
authors.affiliation: Department of Pathology, Taiping People's Hospital of Dongguan, Dongguan Hospital Affiliated to Medical College of Jinan University Dongguan 523905, China.
authors.forename: Can
authors.initials: C
authors.lastname: Chen
authors.affiliation: Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Guandong Medical College Dongguan 523808, China.
authors.forename: Jun-Fa
authors.initials: JF
authors.lastname: Xu
authors.affiliation: Department of Pathology, Sun Yat-sen University Cancer Center Guanzhou 510060, China.
authors.forename: Qiu-Liang
authors.initials: QL
authors.lastname: Wu
keywords: Mucoepidermoid carcinoma; forearm; immunohistochemistry