title: Aplastic anemia in adolescents and young adults.
abstract: Adolescent and young adult patient presentations of aplastic anemia require a particular perspective on both diagnosis and treatment. This unique age group necessitates a thorough diagnostic evaluation to ensure the etiology, acquired or inherited, is sufficiently determined. The treatment options include human leukocyte antigen-identical sibling hematopoietic cell transplantation or immunosuppressive therapy, and both require attention to the specific medical and social needs of these adolescents and young adults. Longitudinal surveillance throughout life for the development of late complications of the disease and treatment is mandatory.
authors.affiliation: Johns Hopkins University School of Medicine, Baltimore, Md., USA.
authors.forename: Amy E
authors.initials: AE
authors.lastname: DeZern
authors.forename: Eva C
authors.initials: EC
authors.lastname: Guinan
mesh_terms: D000741:Anemia, Aplastic / Q000150:complications / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy; D001424:Bacterial Infections / Q000150:complications; D001803:Blood Transfusion; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D009181:Mycoses / Q000150:complications; D015996:Survival Rate
chemical_list: D007166:Immunosuppressive Agents