title: High resolution compression elastography and color doppler sonography in characterization of breast fibroadenoma.
abstract: OBJECTIVE
  To evaluate the use of color Doppler sonography and free hand sonoelastography in the assessment of breast fibroadenomas according to their size and shape.
  
  
  METHODS
  From December 2012 to March 2013 women with 16 solid breast masses, classified as BI-RADS category 3 or 4 were examined with B-mode ultrasound, sonoelastography and color Doppler sonography. Lesions were subdivided according to their shape in round, ovoid or macrolobulated and according to their size (<2.0 cm or ≥2.0 cm). Two readers assessed sonoelastographic findings at 12.5 MHz using the tsukuba elasticity score and results of Doppler sonography using a score of 0, 1 or 2, depending on the degree of perfusion.
  
  
  RESULTS
  Among the 16 examined lesions 3 showed a round shape, 9 were ovoid and in 4 cases a macrolobulated appearance could be seen. No significant differences concerning Tsukuba-score depending on various shapes of fibroadenomas in B-mode sonography could be shown (p = 0.91) and also comparison of Tsukuba-scores and size of masses revealed no significant differences (p = 1.0). Sizes of fibroadenomas ≥2 cm were significantly associated with an increased vascularization of the lesions (p = 0.04) and a macrolobulated appearance in B-mode sonography (p = 0.04).
  
  
  CONCLUSIONS
  The combination of color Doppler sonography and sonoelastography in addition to B-mode sonography leads to an increased accuracy in distinguishing benign from malignant breast masses and to an improvement in characterization of fibroadenomas independent of their shape or size.
authors.affiliation: Department for Clinical Radiology, Ludwig-Maximilians-University Hospital, Munich, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Rjosk-Dendorfer
authors.affiliation: Institute of Pathology, Ludwig-Maximilians-University, Munich, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Reu
authors.affiliation: Department for Clinical Radiology, Ludwig-Maximilians-University Hospital, Munich, Germany.
authors.forename: Z
authors.initials: Z
authors.lastname: Deak
authors.affiliation: Department for Clinical Radiology, Ludwig-Maximilians-University Hospital, Munich, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Hetterich
authors.affiliation: Department of Gynecology and Obstetrics, Ludwig-Maximilians-University Hospital, Munich, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Kolben
authors.affiliation: Department for Clinical Radiology, Ludwig-Maximilians-University Hospital, Munich, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Reiser
authors.affiliation: Department for Clinical Radiology, Ludwig-Maximilians-University Hospital, Munich, Germany.
authors.forename: D A
authors.initials: DA
authors.lastname: Clevert
mesh_terms: D000328:Adult; D001940:Breast / Q000473:pathology; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D018226:Fibroadenoma / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008875:Middle Aged; D015588:Observer Variation; D010477:Perfusion; D015203:Reproducibility of Results; D012189:Retrospective Studies; D018615:Ultrasonography, Doppler, Color / Q000379:methods*; D016217:Ultrasonography, Mammary / Q000379:methods*; D055815:Young Adult
keywords: Fibroadenoma; doppler sonography; elastography; ultrasound