title: The effect of chewing lidocaine soaked gauze on intubation conditions during awake videolaryngoscopy: a randomised controlled trial in the morbidly obese.
abstract: The increasing utilisation of the videolaryngoscope for awake tracheal intubation requires development and assessment of methods to decrease the gag reflex. We hypothesised that chewing gauze soaked with lidocaine would decrease the gag reflex during awake videolaryngoscope tracheal intubation. Twenty four morbidly obese patients assessed as having a potential difficult tracheal intubation were randomised to chew gauze soaked with 20 ml of 2% lidocaine or saline for 3 minutes. All patients then received 20 ml of aerosolised 2% lidocaine and underwent awake videolaryngoscope assisted tracheal intubation. Gagging scores, heart rate and blood pressure were assessed when best laryngeal view was obtained, when the tracheal tube was positioned at the cords, and when the tube was advanced into the trachea. In addition, serum lidocaine levels were measured. The primary outcome was the gagging score at best laryngeal visualisation, which was compared between groups with a Student's t-test. Gagging scores and hemodynamic parameters did not differ between groups, but the saline group had lower plasma levels of lidocaine after the intubation procedure. When used for awake videolaryngoscope assisted tracheal intubation of the morbidly obese, chewing lidocaine soaked gauze does not decrease the amount of gagging as compared to lidocaine aerosolisation, but does increase the plasma levels of lidocaine.
authors.forename: A
authors.initials: A
authors.lastname: Moore
authors.forename: P O
authors.initials: PO
authors.lastname: Hétu
authors.forename: O
authors.initials: O
authors.lastname: Court
authors.forename: W Li Pi
authors.initials: WL
authors.lastname: Shan
authors.forename: R
authors.initials: R
authors.lastname: Hatzakorzian
authors.forename: A
authors.initials: A
authors.lastname: El-Bahrawy
authors.forename: T
authors.initials: T
authors.lastname: Schricker
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal / Q000379:methods*; D007828:Laryngoscopy; D008012:Lidocaine / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid; D020535:Video-Assisted Surgery / Q000379:methods*; D014851:Wakefulness
chemical_list: D008012:Lidocaine