title: Seizures and brain regulatory systems: consciousness, sleep, and autonomic systems.
abstract: Research into the physiologic underpinnings of epilepsy has revealed reciprocal relationships between seizures and the activity of several regulatory systems in the brain. This review highlights recent progress in understanding and using the relationships between seizures and the arousal or consciousness system, the sleep-wake and associated circadian system, and the central autonomic network.
authors.affiliation: *Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.; †Departments of Neurology, Neurobiology and Neurosurgery, Yale School of Medicine, New Haven, Connecticut, U.S.A.; ‡Division of Epilepsy and Clinical Neurophysiology, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, U.S.A.; and §Department of Neurology, Columbia University, New York, New York, U.S.A.
authors.forename: Madineh
authors.initials: M
authors.lastname: Sedigh-Sarvestani
authors.forename: Hal
authors.initials: H
authors.lastname: Blumenfeld
authors.forename: Tobias
authors.initials: T
authors.lastname: Loddenkemper
authors.forename: Lisa M
authors.initials: LM
authors.lastname: Bateman
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology*; D057906:Circadian Clocks; D003243:Consciousness / Q000502:physiology*; D006801:Humans; D012640:Seizures / Q000503:physiopathology* / Q000628:therapy; D012890:Sleep / Q000502:physiology*