title: Endothelial dysfunction after stenting and scaffolding of coronary arteries.
abstract: Coronary artery stenting is associated with endothelial dysfunction, probably caused by the mechanical injury as well as by the tissue reactions triggered by the metal, the polymer and the drug eluted by the stent. The clinical relevance, and the implications, of this dysfunction are still unclear. We revise the literature on this topic and provide the first evidence regarding endothelial dysfunction after implantation of bioresorbable scaffolds.
authors.affiliation: Department of Cardiology and Angiology, University Medical Center Mainz, Germany.
authors.forename: Tommaso
authors.initials: T
authors.lastname: Gori
authors.affiliation: Department of Cardiology and Angiology, University Medical Center Mainz, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Münzel
mesh_terms: D000109:Acetylcholine / Q000737:chemistry; D017130:Angioplasty; D000800:Angioplasty, Balloon / Q000379:methods; D001672:Biocompatible Materials / Q000737:chemistry; D003326:Coronary Circulation; D003331:Coronary Vessels / Q000473:pathology*; D054855:Drug-Eluting Stents; D004730:Endothelium, Vascular / Q000473:pathology; D006801:Humans; D007511:Ischemia / Q000473:pathology; D008670:Metals / Q000737:chemistry; D009569:Nitric Oxide / Q000737:chemistry; D011108:Polymers / Q000737:chemistry; D013314:Stress, Mechanical; D014652:Vascular Diseases / Q000473:pathology*; D014664:Vasodilation
chemical_list: D001672:Biocompatible Materials; D008670:Metals; D011108:Polymers; D009569:Nitric Oxide; D000109:Acetylcholine
keywords: Endothelium/vascular type/nitric oxide; coronary circulation; pathophysiology