title: Sebotropic eruption associated with use of oral kava kava supplement.
abstract: Supplement use is prevalent, and its use is increasing among older adults. Dermatologists need to be aware of the adverse cutaneous effects that can result from herbal supplement use. A 55-year-old man presented with an eruption in a sebotropic distribution after consuming kava kava for 3 weeks, which resolved after discontinuation of the supplement. This case highlights the need for clinicians to consider kava kava in the differential of sebotropic eruptions. The biology, mechanism of action, and potential systemic and cutaneous effects of kava kava are reviewed.
authors.affiliation: Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Huynh
authors.forename: M M
authors.initials: MM
authors.lastname: Asgari
authors.forename: M M
authors.initials: MM
authors.lastname: Moore
mesh_terms: D019587:Dietary Supplements / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology*; D004890:Erythema / Q000139:chemically induced; D005076:Exanthema / Q000139:chemically induced*; D006801:Humans; D020901:Kava / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy / Q000009:adverse effects*; D028321:Plant Preparations / Q000009:adverse effects*; D012627:Sebaceous Glands / Q000187:drug effects*
chemical_list: D028321:Plant Preparations