title: Assessment of women who applied for the uterine transplant project as potential candidates for uterus transplantation.
abstract: OBJECTIVE
  To review the medical charts of women who applied for the uterine transplant project from June 2008 to June 2011 in our hospital retrospectively (18-40 years).
  
  
  METHODS
  The data for 144 women were retrieved, and information was collected on the etiology of uterine factor infertility(UFI); ovarian reserve tests; and accompanying anatomic, infectious, genetic and endocrinological problems.
  
  
  RESULTS
  There were 119 patients with primary amenorrhea and uterovaginal agenesis and 25 patients with a history of hysterectomy. The complete Müllerian agenesis patients formed the largest group of the UFI patients with better anti-Müllerian hormone levels and antral follicle count. Anatomical anomalies such as a solitary pelvic kidney may accompany Mayer-Rokitansky-Kuster-Hauser syndrome (MRKH) and impede surgery. The mean ages in MRKH, hysterectomy and complete androgen insensitivity syndrome (CAIS) cases were 24.7, 35.0 and 34.4 years, respectively. The karyotype analysis showed 46XX (MRKH) in 109 patients and 46XY (CAIS) in 10 of the primary amenorrhea patients.
  
  
  CONCLUSIONS
  Hysterectomy may deteriorate ovarian blood flow and decrease ovarian reserve. Fertility preservation may be considered in young woman undergoing hysterectomy.
authors.affiliation: Department of Obstetrics and Gynecology, Akdeniz University School of Medicine, Antalya, Turkey.
authors.forename: Munire
authors.initials: M
authors.lastname: Erman Akar
authors.forename: Murat
authors.initials: M
authors.lastname: Ozekinci
authors.forename: Ozgul
authors.initials: O
authors.lastname: Alper
authors.forename: Durkadin
authors.initials: D
authors.lastname: Demir
authors.forename: Can
authors.initials: C
authors.lastname: Cevikol
authors.forename: Asli
authors.initials: A
authors.lastname: Meric Bilekdemir
authors.forename: Aylin
authors.initials: A
authors.lastname: Daloglu
authors.forename: Gozde
authors.initials: G
authors.lastname: Ongut
authors.forename: Yesim
authors.initials: Y
authors.lastname: Senol
authors.forename: Sebahat
authors.initials: S
authors.lastname: Ozdem
authors.forename: Gulbahar
authors.initials: G
authors.lastname: Uzun
authors.forename: Guven
authors.initials: G
authors.lastname: Luleci
authors.forename: Gultekin
authors.initials: G
authors.lastname: Suleymanlar
mesh_terms: D058489:46, XX Disorders of Sex Development / Q000601:surgery*; D000328:Adult; D000013:Congenital Abnormalities / Q000601:surgery*; D005260:Female; D006801:Humans; D009095:Mullerian Ducts / Q000002:abnormalities* / Q000601:surgery; D012189:Retrospective Studies; D014599:Uterus / Q000002:abnormalities / Q000637:transplantation*; D055815:Young Adult
keywords: complete Müllerian agenesis; uterine factor infertility; uterus transplantation