title: Towards prenatal biomonitoring in eastern Nigeria: assessing lead levels and anthropometric parameters of newborns.
abstract: The purpose of this study is to measure maternal blood lead level (BLL) and cord BLL in Nigeria and to compare Nigerian data with other data. We investigated the association among maternal and cord BLLs, and some anthropometric parameters of their babies. BLL was measured in the umbilical and maternal blood samples (using inductively coupled plasma / mass spectrometry (ICP-MS)) of 119 women who delivered at three different hospitals in Nnewi, South Eastern Nigeria. Anthropometric variables of the babies (head circumference, abdominal circumference, birth weight, birth length, crown rump length) were measured. Lead was detected at >10 μg/l in 10.9 percent of the maternal and 3.4 percent of the cord blood samples. The maternal BLL was 6.19 ± 2.77(mean ± SD) μg/dl while cord BLL was 4.75 ± 2.59(mean ± SD) μg/dl. With the exception of cord BLL and crown rump length positive correlation (R=0.204, P=0.026), neither the maternal nor the cord BLL showed any significant association with any of the children's anthropometric parameters.
authors.affiliation: Faculty of Medicine, College of Health Sciences, Nnamdi Azikiwe University, Nigeria.
authors.forename: Ejeatuluchukwu
authors.initials: E
authors.lastname: Obi
authors.forename: Orish Ebere
authors.initials: OE
authors.lastname: Orisakwe
authors.forename: Charles
authors.initials: C
authors.lastname: Okafor
authors.forename: Anthony
authors.initials: A
authors.lastname: Igwebe
authors.forename: Joy
authors.initials: J
authors.lastname: Ebenebe
authors.forename: Onyenmechi Johnson
authors.initials: OJ
authors.lastname: Afonne
authors.forename: Francis
authors.initials: F
authors.lastname: Ifediata
authors.forename: Basu
authors.initials: B
authors.lastname: Nils
authors.forename: Jerome
authors.initials: J
authors.lastname: Nriagu
mesh_terms: D000328:Adult; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000097:blood*; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D006801:Humans; D007231:Infant, Newborn; D007854:Lead / Q000097:blood*; D009549:Nigeria; D011247:Pregnancy; D055815:Young Adult
chemical_list: D004785:Environmental Pollutants; D007854:Lead