title: Graphics processing unit-based quantitative second-harmonic generation imaging.
abstract: We adapt a graphics processing unit (GPU) to dynamic quantitative second-harmonic generation imaging. We demonstrate the temporal advantage of the GPU-based approach by computing the number of frames analyzed per second from SHG image videos showing varying fiber orientations. In comparison to our previously reported CPU-based approach, our GPU-based image analysis results in ∼10× improvement in computational time. This work can be adapted to other quantitative, nonlinear imaging techniques and provides a significant step toward obtaining quantitative information from fast in vivo biological processes.
authors.affiliation: University of Illinois at Urbana-Champaign, Department of Mechanical Science and Engineering, Laboratory for Photonics Research of Bio/nano Environments (PROBE), Urbana, Illinois 61801, United States.
authors.forename: Mohammad Mahfuzul
authors.initials: MM
authors.lastname: Kabir
authors.affiliation: University of Illinois at Urbana-Champaign, Department of Mechanical Science and Engineering, Urbana, Illinois 61801, United States.
authors.forename: A S M
authors.initials: AS
authors.lastname: Jonayat
authors.affiliation: University of Illinois at Urbana-Champaign, Department of Electrical and Computer Engineering, Urbana, Illinois 61801, United States.
authors.forename: Sanjay
authors.initials: S
authors.lastname: Patel
authors.affiliation: University of Illinois at Urbana-Champaign, Department of Mechanical Science and Engineering, Laboratory for Photonics Research of Bio/nano Environments (PROBE), Urbana, Illinois 61801, United StatesbUniversity of Illinois at Urbana-Champaign, Department.
authors.forename: Kimani C
authors.initials: KC
authors.lastname: Toussaint
mesh_terms: D000818:Animals; D001940:Breast / Q000737:chemistry; D002584:Cervix Uteri / Q000737:chemistry; D003094:Collagen / Q000737:chemistry; D003196:Computer Graphics; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D018715:Microscopy, Video / Q000379:methods*; D017711:Nonlinear Dynamics; D051381:Rats; D013552:Swine; D013710:Tendons / Q000737:chemistry
chemical_list: D003094:Collagen