title: Pyridine derivatives as insecticides. Part 1: synthesis and toxicity of some pyridine derivatives against cowpea aphid, Aphis craccivora Koch (Homoptera: Aphididae).
abstract: Five pyridine derivatives, namely, N-morpholinium 7,7-dimethyl-3-cyano-4-(4'-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-2-thiolate (1), sodium 5-acetyl-3-amino-4-(4'-methoxyphenyl)-6-methylthieno[2,3-b] pyridine-2-carboxylate (2), piperidinium 3,5-dicyano-2-oxo-4-spirocyclopentane-1,2,3,4-tetrahydropyridine-6-thiolate (3), piperidinium 5-acetyl-3-cyano-4-(4'-methoxyphenyl)-6-methylpyridine-2-thiolate (4), and piperidinium 5-acetyl-4-(4'-chlorophenyl)-3-cyano-6-methyl-pyridine-2-thiolate (5) were prepared in pure state and subjected to the title study. The bioassay results indicated that the insecticidal activity of compound 1 is about 4-fold that of acetamiprid insecticide. The rest of the tested compounds possess moderate to strong aphidicidal activities.
authors.affiliation: Chemistry Department, Faculty of Science, and ‡Plant Protection Department, Faculty of Agriculture, Assiut University , 71516 Assiut, Egypt.
authors.forename: Etify A
authors.initials: EA
authors.lastname: Bakhite
authors.forename: Aly A
authors.initials: AA
authors.lastname: Abd-Ella
authors.forename: Mohamed E A
authors.initials: ME
authors.lastname: El-Sayed
authors.forename: Shaban A A
authors.initials: SA
authors.lastname: Abdel-Raheem
mesh_terms: D000818:Animals; D001042:Aphids / Q000187:drug effects*; D007306:Insecticides / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity*; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry* / Q000633:toxicity*
chemical_list: D007306:Insecticides; D011725:Pyridines; C023666:pyridine
keywords: acetamiprid; insecticides; piperidinium thiolates; pyridines; spiro compounds; thienopyridines