title: Ultrathin Coatings with Change in Reactivity over Time Enable Functional In Vitro Networks Of Insect Neurons.
abstract: It's just not cricket! A novel coating system that enables covalent attachment of biomolecules in a nonfouling environment without use of additional chemical crosslinkers is presented. Concanavalin A is patterned on the coatings to direct cell adhesion and growth of neurons from the cricket Gryllus bimaculatus and generate functional, patterned in vitro insect neuronal networks for the first time.
authors.affiliation: Institute for Bio and Nanosystems (IBN-2), Forschungszentrum Jülich 52425 Jülich (Germany).
authors.forename: Anna
authors.initials: A
authors.lastname: Reska
authors.forename: Peter
authors.initials: P
authors.lastname: Gasteier
authors.forename: Petra
authors.initials: P
authors.lastname: Schulte
authors.forename: Martin
authors.initials: M
authors.lastname: Moeller
authors.forename: Andreas
authors.initials: A
authors.lastname: Offenhäusser
authors.forename: Juergen
authors.initials: J
authors.lastname: Groll
keywords: biocompatible materials; biosensors; hydrogels; microcontact printing; networks; thin films