title: Biologics in polymyositis and dermatomyositis-associated interstitial lung disease.
abstract: Interstitial lung disease (ILD) is one of the most common complications of polymyositis (PM) and dermatomyositis (DM). It is always progressive and does not respond to conventional immunosuppressive agent treatment. Biologics are commonly used in treatment of rheumatic diseases. They are also used in polymyositis and dermatomyositis associated interstitial lung disease. This review will focus on the updated use of biologics in PM/DM-ILD.
authors.forename: Yuechi
authors.initials: Y
authors.lastname: Sun
authors.forename: Yan
authors.initials: Y
authors.lastname: He
authors.forename: Yuan
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Rheumatology, The First Affiliated Hospital, Xiamen University, No. 55, Zhenhai Road, Xiamen 361003, China. guixiu.shi@gmail.com.
authors.forename: Guixiu
authors.initials: G
authors.lastname: Shi
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D015703:Antigens, CD / Q000276:immunology; D018951:Antigens, CD20 / Q000276:immunology; D000951:Antigens, Neoplasm / Q000276:immunology; D001688:Biological Products / Q000627:therapeutic use*; D000074301:CD52 Antigen; D003882:Dermatomyositis / Q000150:complications / Q000188:drug therapy*; D006023:Glycoproteins / Q000276:immunology; D006801:Humans; D015850:Interleukin-6 / Q000276:immunology; D017563:Lung Diseases, Interstitial / Q000188:drug therapy* / Q000209:etiology; D017285:Polymyositis / Q000150:complications / Q000188:drug therapy*; D017472:Receptors, Interleukin-1 / Q000037:antagonists & inhibitors / Q000276:immunology; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors / Q000276:immunology; D000093242:Interleukin-6 Inhibitors
chemical_list: D000911:Antibodies, Monoclonal; D015703:Antigens, CD; D018951:Antigens, CD20; D000951:Antigens, Neoplasm; D001688:Biological Products; D000074301:CD52 Antigen; D006023:Glycoproteins; D015850:Interleukin-6; D017472:Receptors, Interleukin-1; D014409:Tumor Necrosis Factor-alpha; D000093242:Interleukin-6 Inhibitors; C000613862:CD52 protein, human; C508600:IL6 protein, human