title: Recent progress and prospects in Sasang constitutional medicine: a traditional type of physiome-based treatment.
abstract: The history of the constitution perspective in medical care dates back thousands of years and extends from the East to the West. Among the various forms of constitutional medicine, Sasang constitutional medicine (SCM) is a holistic, tailored medical approach that is based on a well-structured theoretical system that includes physiopathological disciplines. Scientific evidence has demonstrated that SCM typology has a constitution-specific basis in anthropometrics, physiological characteristics, disease vulnerability, and genetic origins. Furthermore, the recent rise of systems biology, which requires whole body modeling, uses a state-of-the-art approach in interpreting the holistic spirit of Oriental medicine. This article aims to provide an overview of the recent achievements in SCM research and to discuss how the concept of balance in SCM may contribute to the development of large scale modeling in systems biology.
authors.affiliation: Department of Medical Research, Korea Institute of Oriental Medicine, Yuseong-gu, Daejeon 305-811, Republic of Korea.
authors.forename: Jong Yeol
authors.initials: JY
authors.lastname: Kim
authors.affiliation: Department of Physiology, Anatomy & Genetics, University of Oxford, Parks Road, Oxford OX1 3PT, UK. Electronic address: denis.noble@dpag.ox.ac.uk.
authors.forename: Denis
authors.initials: D
authors.lastname: Noble
mesh_terms: D001824:Body Constitution / Q000502:physiology*; D003198:Computer Simulation; D005544:Forecasting; D006694:Holistic Health / Q000639:trends*; D008954:Models, Biological; D066230:Patient-Specific Modeling / Q000639:trends*; D049490:Systems Biology / Q000639:trends*
keywords: Biology; Constitutional; MedicineSasang; MedicineSystems; Oriental