title: Oral acyclovir induced acute renal failure.
abstract: BACKGROUND
  The study aimed to investigate the clinical characteristics of acute renal failure (ARF) caused by oral acyclovir.
  
  
  METHODS
  A 45-year-old Chinese male patient with acyclovir-induced ARF suffered from abdominal pain for one day. The pain was extended to the epigastric area from the right lower quadrant. Transient oliguria was seen in addition to microscopic hematuria and proteinuria. The serum creatinine concentration was 304 μmol/L. Eight days before the occurrence of ARF, the patient took oral acyclovir for facial neuritis.
  
  
  RESULTS
  His renal function was restored completely following the discontinuation of acyclovir, with continuous renal replacement therapy for 54 hours and some symptomatic treatment.
  
  
  CONCLUSIONS
  The presentation of acute renal failure caused by acyclovir can be diverse, but the prognosis is good after active treatment.
authors.affiliation: ICU, Tongde Hospital of Zhejiang Province, Hangzhou 310012, China (Meng JB, Zhang G); ICU, First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310006, China (Zheng X, Fang Q).
authors.forename: Jian-Biao
authors.initials: JB
authors.lastname: Meng
authors.affiliation: ICU, Tongde Hospital of Zhejiang Province, Hangzhou 310012, China (Meng JB, Zhang G); ICU, First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310006, China (Zheng X, Fang Q).
authors.forename: Xia
authors.initials: X
authors.lastname: Zheng
authors.affiliation: ICU, Tongde Hospital of Zhejiang Province, Hangzhou 310012, China (Meng JB, Zhang G); ICU, First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310006, China (Zheng X, Fang Q).
authors.forename: Gen
authors.initials: G
authors.lastname: Zhang
authors.affiliation: ICU, Tongde Hospital of Zhejiang Province, Hangzhou 310012, China (Meng JB, Zhang G); ICU, First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310006, China (Zheng X, Fang Q).
authors.forename: Qiang
authors.initials: Q
authors.lastname: Fang
keywords: Acute renal failure; Acyclovir; Continuous vein-vein hemofiltration; oral