title: Clinical profile and outcome of clinical BCG disease in infants.
abstract: OBJECTIVE
  To describe the clinical profile, immunological status and outcome of BCG disease in infants.
  
  
  METHODS
  All infants with a diagnosis of BCG disease in a period of 17 months were followed up.
  
  
  RESULTS
  Among 25 infants with BCG disease; 19 had local/regional involvement and 6 had suspected or confirmed distant/disseminated disease, Mean (range) age of presentation was 3.6 (1.5-9) months. Two of 6 infants with disseminated disease required second-line anti-tubercular treatment. One infant with confirmed disseminated disease had INFg R1 receptor deficiency. There was no mortality.
  
  
  CONCLUSIONS
  Most infants with BCG- related disease have local or regional disease.
authors.affiliation: Department of Pediatrics, St. John's Medical College Hospital, Bangalore, India. Correspondence to: Dr CK Indumathi, Associate Professor, Department of Pediatrics, St John's Medical College Hospital, Sarjapur Road, Bangalore 560 034, Karnataka, India. ckindumathi@gmail.com.
authors.forename: C K
authors.initials: CK
authors.lastname: Indumathi
authors.forename: Priyadarashini M
authors.initials: PM
authors.lastname: Kowtal
authors.forename: R N
authors.initials: RN
authors.lastname: Poornima
authors.forename: Sanjiv
authors.initials: S
authors.lastname: Lewin
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use; D001500:BCG Vaccine / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D008206:Lymphatic Diseases; D009163:Mycobacterium bovis; D014376:Tuberculosis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology / Q000503:physiopathology
chemical_list: D000995:Antitubercular Agents; D001500:BCG Vaccine