title: Comparison of bacterial endotoxin lipopolysaccharide concentrations in the blood, ovarian follicular fluid and uterine fluid: a clinical case of bovine metritis.
abstract: We investigated the concentration of the bacterial endotoxin lipopolysaccharide (LPS) in the blood, ovarian follicular fluid and uterine fluid of a clinical case of bovine metritis. A 2-year-old lactating Holstein cow exhibited continuous fever >39.5°C for more than 2 weeks after normal calving. The cow produced a fetid, watery, red-brown uterine discharge from the vagina and was diagnosed with metritis. The LPS concentrations in plasma and uterine fluid were 0.94 and 6.34 endotoxin units (EU)/ml, respectively. One of seven follicles showed an extremely high level of LPS (12.40 EU/ml) compared to the other follicles (0.62-0.97 EU/ml). These results might suggest the presence of high concentration of LPS in follicles in cows with postpartum metritis.
authors.affiliation: Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Japan.
authors.forename: Fumie
authors.initials: F
authors.lastname: Magata
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Ishida
authors.forename: Akio
authors.initials: A
authors.lastname: Miyamoto
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Furuoka
authors.forename: Hisashi
authors.initials: H
authors.lastname: Inokuma
authors.forename: Takashi
authors.initials: T
authors.lastname: Shimizu
mesh_terms: D000818:Animals; D001826:Body Fluids / Q000737:chemistry*; D002417:Cattle; D002418:Cattle Diseases / Q000097:blood*; D004716:Endometritis / Q000097:blood / Q000662:veterinary*; D005260:Female; D008070:Lipopolysaccharides / Q000097:blood* / Q000737:chemistry*; D006080:Ovarian Follicle; D014599:Uterus / Q000473:pathology
chemical_list: D008070:Lipopolysaccharides