title: Harmonic curved shears system prevent of bile leakage after liver resection in a pig model.
abstract: We evaluated the efficacy of TachoComb (TC) collagen fleece and Harmonic Focus (HF) shears in a pig liver resection model. Pigs were divided into 3 groups of 7, in which vessels were tied with silk and TC was applied to the cut surfaces (Silk+TC group), sealed and sheared with HF and TC (HF+TC group), or sealed using HF alone (HF-TC group). After 1 month, we conducted a histologic evaluation and recorded the incidence of bile leakage with infected collections at the liver cut surface. Six pigs were evaluated in each group. In the Silk+TC group, 4 of the 6 pigs had infected collections at the cut surface. Histologically, the silk had remained under the fibrotic tissue, which contained remnants of TC fragments. In the HF+TC group, 5 of the 6 pigs also had infected collections, and histologically, TC had remained in the hard fibrotic tissues. In the HF-TC group, none of the 6 pigs had infected collections, and the histologic findings were normal. Use of the HF alone may be an effective method for preventing bile leakage in infected collections after liver resection.
authors.affiliation: Second Department of Surgery, Dokkyo Medical University, Mibu, Japan.
authors.forename: Mitsugi
authors.initials: M
authors.lastname: Shimoda
authors.forename: Yoshimi
authors.initials: Y
authors.lastname: Iwasaki
authors.forename: Keiichi
authors.initials: K
authors.lastname: Kubota
mesh_terms: D000818:Animals; D001646:Bile; D003094:Collagen / Q000627:therapeutic use*; D005340:Fibrinogen; D006498:Hepatectomy; D008297:Male; D023421:Models, Animal; D011183:Postoperative Complications / Q000517:prevention & control*; D013552:Swine
chemical_list: D005340:Fibrinogen; D003094:Collagen
keywords: Biloma; Fibrinogen sheet; Liver resection; Pig; Shears system