title: [Correlation analysis on retrobulbar vascular hemodynamic characteristics and carotid artery color Doppler ultrasonographic features of amaurosis fugax].
abstract: OBJECTIVE
  To investigate the correlation of amaurosis fugax and carotid stenosis as well as posterior ocular blood vessel hemodynamic changes.
  
  
  METHODS
  Case series studies. 32 patients (19 men and 13 women whose age were 50 to 80 years old and average age was 64.31 ± 8.15) who were diagnosed as amaurosis fugax with 32 eyes were enrolled from 2011.5-2012.12. During the same period 30 cases without posterior ocular ischemic diseases were collected as the control group. Their ophthalmic artery, central retinal artery and carotid artery were examinated by color Doppler ultrasound, to detect vascular peak systolic velocity, end diastolic velocity, resistance index, the degree of carotid stenosis, carotid artery plaque area and type. All data were analyzed by chi-square test and t-test.
  
  
  RESULTS
  PSV (25.95 ± 2.45) cm/s, EDV (6.01 ± 0.87) cm/s of the ophthalmic artery in AmF group were lower compared with the control group [PSV:(27.53 ± 1.41) cm/s, EDV: (6.89 ± 0.56) cm/s]. The differences were statistically significant (t = 3.087, 0.712, P = 0.003, 0.048). There was no statistical difference of RI between AmF and the control group (t = 0.188, P = 0.852) . PSV (7.13 ± 0.96) cm/s, EDV (1.78 ± 0.26) cm/s of the central retinal artery in AmF group were lower compared with the control group[PSV:(8.23 ± 0.92) cm/s, EDV:(2.13 ± 0.29) cm/s]. The differences were statistically significant (t = 4.648, 4.976, P = 0.000, 0.000). There was no statistical difference of RI between AmF and the control group (t = 0.180, P = 0.855). Detection rate of carotid artery moderately and severe stenosis (59.4%) was significantly higher compared with the control group (6.7%) . The difference was statistically significant (χ(2) = 19.205, P = 0.000).
  
  
  CONCLUSIONS
  The blood flow velocity of ophthalmic artery and central retinal artery in amaurosis fugax patients reduced significantly, while the resistance was normal. About 60% of the patients had carotid artery moderately and severe stenosis. There was significant correlation between amaurosis fugax and carotid artery stenosis.
authors.affiliation: Department of Ophthalmology, The Centrol Hospital, Cangzhou 061000, China.
authors.forename: Xueyan
authors.initials: X
authors.lastname: Feng
authors.affiliation: Department of Ophthalmology, The Centrol Hospital, Cangzhou 061000, China. Email: yecunxi@yahoo.com.cn.
authors.forename: Cunxi
authors.initials: C
authors.lastname: Ye
authors.affiliation: Department of Ophthalmology, The Centrol Hospital, Cangzhou 061000, China.
authors.forename: Mingchun
authors.initials: M
authors.lastname: Mu
authors.affiliation: Department of Ophthalmology, The Centrol Hospital, Cangzhou 061000, China.
authors.forename: Haiting
authors.initials: H
authors.lastname: Chen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D020757:Amaurosis Fugax / Q000000981:diagnostic imaging / Q000503:physiopathology*; D001783:Blood Flow Velocity / Q000502:physiology; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000503:physiopathology*; D016893:Carotid Stenosis / Q000000981:diagnostic imaging*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009880:Ophthalmic Artery / Q000000981:diagnostic imaging / Q000503:physiopathology*; D012161:Retinal Artery / Q000000981:diagnostic imaging / Q000503:physiopathology*; D014463:Ultrasonography; D014655:Vascular Resistance / Q000502:physiology