title: Men regret anabolic steroid use due to a lack of comprehension regarding the consequences on future fertility.
abstract: We examined whether men with anabolic-steroid-induced hypogonadism (ASIH) seeking testosterone supplementation therapy (TST) regretted their decision to use anabolic-androgenic steroids (AAS) and what their reasons were for this regret. An anonymous, prospective survey was distributed to 382 men seeking follow-up treatment for hypogonadism. Prior AAS use was confirmed by self-report, and men were categorised based upon whether they regretted (R) or did not regret (NR) their use of AAS. The average patient age was 40 ± 0.9 years (n = 79) and 15.2% expressed regret over AAS use. No demographic differences were identified between those who regretted AAS use (n = 12) and those who did not (n = 67). Regret was not related to ASIH diagnosis or to AAS-related side effects like increased aggression, mood disorders, erectile dysfunction, acne, fluid retention or dyslipidemia. Those who regretted AAS use were significantly more likely to have not comprehended the negative impact on future fertility (P < 0.030). Actual fertility issues were comparable in men who regretted AAS use (16.7%) and those who did not (13%). A total of 15.2% of men regretted using AAS. A lack of awareness regarding the negative long-term effects on fertility was the primary factor related to regret of AAS use in men with ASIH.
authors.affiliation: Urology of Indiana, Male Reproductive Endocrinology and Surgery, Carmel, IN, USA.
authors.forename: J R
authors.initials: JR
authors.lastname: Kovac
authors.affiliation: Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA.
authors.forename: J
authors.initials: J
authors.lastname: Scovell
authors.affiliation: Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA.
authors.forename: R
authors.initials: R
authors.lastname: Ramasamy
authors.affiliation: Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA.
authors.forename: S
authors.initials: S
authors.lastname: Rajanahally
authors.affiliation: Department of Urology, University of North Carolina, Chapel Hill, NC, USA.
authors.forename: R M
authors.initials: RM
authors.lastname: Coward
authors.affiliation: Department of Urology, University of Virginia, Charlottesville, VA, USA.
authors.forename: R P
authors.initials: RP
authors.lastname: Smith
authors.affiliation: Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA.
authors.forename: L I
authors.initials: LI
authors.lastname: Lipshultz
mesh_terms: D000328:Adult; D045930:Anabolic Agents / Q000009:adverse effects*; D004300:Doping in Sports / Q000523:psychology*; D004644:Emotions; D006801:Humans; D007248:Infertility, Male / Q000139:chemically induced* / Q000523:psychology; D008297:Male; D011446:Prospective Studies; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires
chemical_list: D045930:Anabolic Agents
keywords: Anabolic steroids; hypogonadism; infertility; regret; testosterone