title: Posttraumatic Stress Disorder following childhood abuse increases the severity of suicide attempts.
abstract: OBJECTIVE
  Posttraumatic Stress Disorder (PTSD) and childhood abuse are both consistently associated with a higher risk for suicide attempts. We hypothesize that among patients reporting childhood abuse, PTSD diagnoses are correlated with an increased severity of suicidal features.
  
  
  METHODS
  We investigated 726 adult patients who had attempted suicide. These participants were assessed on lifetime clinical diagnoses and childhood abuse. The association of PTSD and childhood abuse dimensions with age at first suicide attempt, number of suicide attempts, violent attempts, serious attempts and suicide intent was studied. An adjusted multinomial logistic regression was performed to ascertain if childhood abuse and PTSD increased the severity of the suicidal behavior when combined.
  
  
  RESULTS
  Several types of childhood abuse (emotional, physical and sexual abuse) when combined with a lifetime diagnosis of PTSD showed an increased risk for more suicide attempts, serious attempts, and a higher level of suicidal intent compared with the absence of any or both risk factors.
  
  
  CONCLUSIONS
  The combination of PTSD and childhood abuse should be investigated in clinical settings due to an augmented risk for more severe suicidal behavior.
authors.affiliation: Inserm U1061, Ho^pital La Colombiere, Montpellier, France; IIS-Fundacion Jimenez Diaz, Department of Psychiatry, CIBERSAM, Madrid, Spain; Department of Emergency Psychiatry, CHRU Montpellier, France. Electronic address: jorgecastroman@gmail.com.
authors.forename: Jorge
authors.initials: J
authors.lastname: Lopez-Castroman
authors.affiliation: Inserm U1061, Ho^pital La Colombiere, Montpellier, France.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Jaussent
authors.affiliation: Inserm U1061, Ho^pital La Colombiere, Montpellier, France.
authors.forename: Severine
authors.initials: S
authors.lastname: Beziat
authors.affiliation: Inserm U1061, Ho^pital La Colombiere, Montpellier, France; Department of Emergency Psychiatry, CHRU Montpellier, France; University of Montpellier 1, Montpellier, France.
authors.forename: Sebastien
authors.initials: S
authors.lastname: Guillaume
authors.affiliation: IIS-Fundacion Jimenez Diaz, Department of Psychiatry, CIBERSAM, Madrid, Spain; Department of Psychiatry at the New York State Psychiatric Institute and Columbia University, NY, USA.
authors.forename: Enrique
authors.initials: E
authors.lastname: Baca-Garcia
authors.affiliation: Inserm U1061, Ho^pital La Colombiere, Montpellier, France; Department of Emergency Psychiatry, CHRU Montpellier, France; University of Montpellier 1, Montpellier, France.
authors.forename: Emilie
authors.initials: E
authors.lastname: Olié
authors.affiliation: Inserm U1061, Ho^pital La Colombiere, Montpellier, France; Department of Emergency Psychiatry, CHRU Montpellier, France; University of Montpellier 1, Montpellier, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Courtet
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002649:Child Abuse / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013313:Stress Disorders, Post-Traumatic / Q000150:complications / Q000523:psychology*; D059020:Suicidal Ideation; D013406:Suicide, Attempted / Q000523:psychology*; D014754:Violence / Q000523:psychology*; D055815:Young Adult
keywords: Childhood abuse; Posttraumatic Stress Disorders; Suicidal behavior