title: The pulse duration of electrical stimulation influences H-reflexes but not corticospinal excitability for tibialis anterior.
abstract: The afferent volley generated by neuromuscular electrical stimulation (NMES) influences corticospinal (CS) excitability and frequent NMES sessions can strengthen CS pathways, resulting in long-term improvements in function. This afferent volley can be altered by manipulating NMES parameters. Presently, we manipulated one such parameter, pulse duration, during NMES over the common peroneal nerve and assessed the influence on H-reflexes and CS excitability. We hypothesized that compared with shorter pulse durations, longer pulses would (i) shift the H-reflex recruitment curve to the left, relative to the M-wave curve; and (ii) increase CS excitability more. Using 3 pulse durations (50, 200, 1000 μs), M-wave and H-reflex recruitment curves were collected and, in separate experiments, CS excitability was assessed by comparing motor evoked potentials elicited before and after 30 min of NMES. Despite finding a leftward shift in the H-reflex recruitment curve when using the 1000 μs pulse duration, consistent with a larger afferent volley for a given efferent volley, the increases in CS excitability were not influenced by pulse duration. Hence, although manipulating pulse duration can alter the relative recruitment of afferents and efferents in the common peroneal nerve, under the present experimental conditions it is ineffective for maximizing CS excitability for rehabilitation.
authors.affiliation: a Centre for Neuroscience, University of Alberta, 4-142 Katz Group Centre, Edmonton, AB T6G 2E1, Canada.
authors.forename: Alyssa R
authors.initials: AR
authors.lastname: Hindle
authors.forename: Jenny W H
authors.initials: JW
authors.lastname: Lou
authors.forename: David F
authors.initials: DF
authors.lastname: Collins
mesh_terms: D000293:Adolescent; D000328:Adult; D004558:Electric Stimulation; D004576:Electromyography; D005260:Female; D006181:H-Reflex / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000294:innervation*; D011712:Pyramidal Tracts / Q000502:physiology*; D013977:Tibia / Q000294:innervation*; D013997:Time Factors; D055815:Young Adult
keywords: H-reflex; corticospinal excitability; excitabilité cortico-spinale; neuromuscular electrical stimulation; neuroplasticity; neuroplasticité; rehabilitation; réadaptation; réflexe H; stimulation neuromusculaire électrique