title: Thermal-mechanical deformation modelling of soft tissues for thermal ablation.
abstract: Modeling of thermal-induced mechanical behaviors of soft tissues is of great importance for thermal ablation. This paper presents a method by integrating the heating process with thermal-induced mechanical deformations of soft tissues for simulation and analysis of the thermal ablation process. This method combines bio-heat transfer theories, constitutive elastic material law under thermal loads as well as non-rigid motion dynamics to predict and analyze thermal-mechanical deformations of soft tissues. The 3D governing equations of thermal-mechanical soft tissue deformation are discretized by using the finite difference scheme and are subsequently solved by numerical algorithms. Experimental results show that the proposed method can effectively predict the thermal-induced mechanical behaviors of soft tissues, and can be used for the thermal ablation therapy to effectively control the delivered heat energy for cancer treatment.
authors.affiliation: School of Aerospace, Mechanical and Manufacturing Engineering, RMIT University, Bundoora, VIC 3083, Australia.
authors.forename: Xin
authors.initials: X
authors.lastname: Li
authors.affiliation: School of Aerospace, Mechanical and Manufacturing Engineering, RMIT University, Bundoora, VIC 3083, Australia.
authors.forename: Yongmin
authors.initials: Y
authors.lastname: Zhong
authors.affiliation: School of Aerospace, Mechanical and Manufacturing Engineering, RMIT University, Bundoora, VIC 3083, Australia.
authors.forename: Reza
authors.initials: R
authors.lastname: Jazar
authors.affiliation: School of Aerospace, Mechanical and Manufacturing Engineering, RMIT University, Bundoora, VIC 3083, Australia.
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Subic
mesh_terms: D000818:Animals; D001831:Body Temperature / Q000502:physiology* / Q000528:radiation effects*; D003198:Computer Simulation; D003238:Connective Tissue / Q000502:physiology* / Q000528:radiation effects*; D004735:Energy Transfer / Q000502:physiology* / Q000528:radiation effects; D006244:Hardness / Q000502:physiology / Q000528:radiation effects; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D008954:Models, Biological; D011829:Radiation Dosage; D013814:Thermal Conductivity
keywords: Thermal ablation; bio-heat transfer; soft tissue; thermo-mechanical deformation