title: [Features of anovulatory infertility patients of gan-yin deficiency syndrome: a primary exploration].
abstract: OBJECTIVE
  To explore the laws of anovulatory infertility patients of Gan-yin deficiency syndrome (GYDS), and to analyze the correlation between GYDS and partial sex hormones and metabolic parameters.
  
  
  METHODS
  Recruited were 103 anovulatory infertility patients, including 48 of GYDS and 55 of non-GYDS. At the same time, 20 healthy pluripara at the child-bearing period were recruited as the control group. The body mass index (BMI) and waist to hip ratio (WHR) were measured. Serum levels of luteinizing hormone (LH), follicle stimulating hormone (FSH), testosterone (T), prolactin (PRL), estradiol (E2), sex hormone binding globulin (SHBG), fasting blood glucose (FBG), fasting insulin (FINS), total cholesterol (TC), triglyceride (TG), low density lipoprotein-cholesterol (LDL-C), high density lipoprotein-cholesterol (HDL-C), and leptin were detected. The inter-group difference of the above indices was compared between the two groups.
  
  
  RESULTS
  Levels of BMI, FINS, HOMA-IRI, leptin, TC, TG, LDL-C, T, PRL, and LH were higher in the GYDS group and the non-GDS group than in the control group (P < 0.01, P < 0.05), while SHBG was lower in the GYDS group and the non-GYDS group than in the control group (P < 0.01). Only the PRL level was higher in the GYDS group than in the non-GYDS group (P < 0.01).
  
  
  CONCLUSIONS
  Gan-yin deficiency is a predominant manifestation in anovulatory infertility patients. Partial disorder of some sex hormones and metabolic derangement might be common pathological factors for anovulatory infertility, while increased PRL levels was dominant in GYDS.
authors.forename: Xiao-Ling
authors.initials: XL
authors.lastname: Zeng
authors.forename: Xing-Juan
authors.initials: XJ
authors.lastname: Wang
authors.forename: Ling
authors.initials: L
authors.lastname: Jin
authors.forename: Ming-Jun
authors.initials: MJ
authors.lastname: Yu
mesh_terms: D000328:Adult; D000858:Anovulation / Q000378:metabolism; D015992:Body Mass Index; D016022:Case-Control Studies; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood; D006801:Humans; D007247:Infertility, Female / Q000378:metabolism; D008055:Lipids / Q000097:blood; D011388:Prolactin / Q000097:blood; D016710:Yin Deficiency
chemical_list: D012739:Gonadal Steroid Hormones; D008055:Lipids; D011388:Prolactin