title: NMD: nonsense-mediated defense.
abstract: Initially described as an RNA surveillance pathway, nonsense-mediated decay (NMD) is also recognized to function in the regulation of host gene expression. In this issue of Cell Host & Microbe, three studies describe NMD-mediated defense strategies of plants and mammalian cells in response to pathogen infection.
authors.affiliation: Center for Plant Molecular Biology (ZMBP), University of Tübingen, Auf der Morgenstelle 32, 72076 Tübingen, Germany. Electronic address: awachter@zmbp.uni-tuebingen.de.
authors.forename: Andreas
authors.initials: A
authors.lastname: Wachter
authors.affiliation: Center for Plant Molecular Biology (ZMBP), University of Tübingen, Auf der Morgenstelle 32, 72076 Tübingen, Germany.
authors.forename: Lisa
authors.initials: L
authors.lastname: Hartmann
mesh_terms: D018354:Alphavirus Infections / Q000821:virology*; D017360:Arabidopsis / Q000235:genetics* / Q000276:immunology*; D002352:Carrier Proteins / Q000378:metabolism*; D006801:Humans; D059365:Nonsense Mediated mRNA Decay; D010935:Plant Diseases / Q000821:virology*; D017863:Potexvirus / Q000235:genetics*; D044224:Pseudomonas syringae / Q000502:physiology*; D020365:RNA Helicases; D012367:RNA, Viral / Q000235:genetics*; D011971:Receptors, Immunologic / Q000235:genetics* / Q000276:immunology*; D012672:Semliki forest virus / Q000502:physiology*; D015534:Trans-Activators / Q000378:metabolism*; D014779:Virus Replication
chemical_list: D002352:Carrier Proteins; D012367:RNA, Viral; D011971:Receptors, Immunologic; C515801:SMG5 protein, human; C494578:SMG7 protein, human; D015534:Trans-Activators; D020365:RNA Helicases; C101828:UPF1 protein, human