title: Early tracheotomy for acute severe asthma.
abstract: BACKGROUND
  Few studies have reported the effects of early tracheotomy in acute severe asthmatic patients. We report two patients with acute severe asthma who were successfully treated with early tracheotomy.
  
  
  METHODS
  The two patients with acute severe asthma were retrospectively reviewed. They had been treated at the Department of Emergency and Critical Care, Renji Hospital, Shanghai Jiaotong University School of Medicine.
  
  
  RESULTS
  They developed progressively hypercapnia and severe acidosis, and were not improved after conventional therapies. Early tracheotomy after mechanical ventilation decreased airway resistance and work of breathing, and corrected hypercapnia and acidosis. Adequate gas exchange was maintained after tracheotomy. The two patients were subsequently weaned from mechanical ventilation and discharged.
  
  
  CONCLUSIONS
  Early tracheotomy could be a valuable approach in certain patients with severe asthma.
authors.affiliation: Department of Emergency and Critical Care, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China.
authors.forename: Huan
authors.initials: H
authors.lastname: Huang
authors.affiliation: Department of Emergency and Critical Care, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China.
authors.forename: Xin-Hui
authors.initials: XH
authors.lastname: Xu
authors.affiliation: Department of Emergency and Critical Care, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Department of Emergency and Critical Care, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China.
authors.forename: Li-Xiong
authors.initials: LX
authors.lastname: Lu
authors.affiliation: Department of Emergency and Critical Care, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China.
authors.forename: Chang-Qing
authors.initials: CQ
authors.lastname: Zhu
keywords: Acute severe asthma; Early tracheotomy; Extubation; Mechanical ventilation; Work of breathing