title: Sex, stress and the brain: interactive actions of hormones on the developing and adult brain.
abstract: The brain is a target of steroid hormone actions that affect brain architecture, molecular and neurochemical processes, behavior and neuroprotection via both genomic and non-genomic actions. Estrogens have such effects throughout the brain and this article provides an historical and current view of how this new view has come about and how it has affected the study of sex differences, as well as other areas of neuroscience, including the effects of stress on the brain.
authors.affiliation: Alfred E. Mirsky Professor, Head, Harold and Margaret Milliken Hatch, Laboratory of Neuroendocrinology, The Rockefeller University , New York, NY , USA.
authors.forename: B S
authors.initials: BS
authors.lastname: McEwen
mesh_terms: D000328:Adult; D000367:Age Factors; D001921:Brain / Q000254:growth & development / Q000502:physiology*; D004967:Estrogens / Q000502:physiology*; D005260:Female; D012739:Gonadal Steroid Hormones / Q000502:physiology*; D006728:Hormones / Q000502:physiology; D006801:Humans; D008297:Male; D009473:Neuronal Plasticity / Q000502:physiology; D012727:Sex Characteristics; D013312:Stress, Physiological / Q000502:physiology*
chemical_list: D004967:Estrogens; D012739:Gonadal Steroid Hormones; D006728:Hormones
keywords: BRAIN; ESTROGENS; NEUROCHEMICAL PROCESSES; SEX; STRESS