title: Breast ultrasound despeckling using anisotropic diffusion guided by texture descriptors.
abstract: Breast ultrasound (BUS) is considered the most important adjunct method to mammography for diagnosing cancer. However, this image modality suffers from an intrinsic artifact called speckle noise, which degrades spatial and contrast resolution and obscures the screened anatomy. Hence, it is necessary to reduce speckle artifacts before performing image analysis by means of computer-aided diagnosis systems, for example. In addition, the trade-off between smoothing level and preservation of lesion contour details should be addressed by speckle reduction schemes. In this scenario, we propose a BUS despeckling method based on anisotropic diffusion guided by Log-Gabor filters (ADLG). Because we assume that different breast tissues have distinct textures, in our approach we perform a multichannel decomposition of the BUS image using Log-Gabor filters. Next, the conduction coefficient of anisotropic diffusion filtering is computed using texture responses instead of intensity values as stated originally. The proposed algorithm is validated using both synthetic and real breast data sets, with 900 and 50 images, respectively. The performance measures are compared with four existing speckle reduction schemes based on anisotropic diffusion: conventional anisotropic diffusion filtering (CADF), speckle-reducing anisotropic diffusion (SRAD), texture-oriented anisotropic diffusion (TOAD), and interference-based speckle filtering followed by anisotropic diffusion (ISFAD). The validity metrics are the Pratt's figure of merit, for synthetic images, and the mean radial distance (in pixels), for real sonographies. Figure of merit and mean radial distance indices should tend toward '1' and '0', respectively, to indicate adequate edge preservation. The results suggest that ADLG outperforms the four speckle removal filters compared with respect to simulated and real BUS images. For each method--ADLG, CADF, SRAD, TOAD and ISFAD--the figure of merit median values are 0.83, 0.40, 0.39, 0.51 and 0.59, and the mean radial distance median results are 4.19, 6.29, 6.39, 6.43 and 5.88.
authors.affiliation: Technology Information Laboratory, Center for Research and Advanced Studies of the National Polytechnic Institute, Ciudad Victoria, Tamaulipas, Mexico. Electronic address: wgomez@tamps.cinvestav.mx.
authors.forename: Wilfrido
authors.initials: W
authors.lastname: Gómez Flores
authors.affiliation: Biomedical Engineering Program/COPPE, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Wagner Coelho de Albuquerque
authors.initials: WC
authors.lastname: Pereira
authors.affiliation: Biomedical Engineering Program/COPPE, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Antonio Fernando Catelli
authors.initials: AF
authors.lastname: Infantosi
mesh_terms: D016880:Anisotropy; D016477:Artifacts; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D016217:Ultrasonography, Mammary / Q000379:methods*
keywords: Anisotropic diffusion; Breast ultrasound; Log–Gabor filters; Speckle filtering; Texture features