title: Bridging the gap between academic research and regulatory health risk assessment of Endocrine Disrupting Chemicals.
abstract: Regulatory risk assessment is traditionally based primarily on toxicity studies conducted according to standardized and internationally validated test guidelines. However, health risk assessment of endocrine disrupting chemicals (EDCs) is argued to rely on the efficient integration of findings from academic research. The aim of this review was to provide an overview of current developments to facilitate the use of academic research in regulatory risk assessment of chemicals and how certain aspects of study design and reporting are particularly important for the risk assessment process. By bridging the gap between academic research and regulatory health risk assessment of EDCs, scientific uncertainty in risk assessment conclusions can be reduced, allowing for better targeted policy decisions for chemical risk reduction.
authors.affiliation: Department of Applied Environmental Science, Stockholm University, 106 91 Stockholm, Sweden. Electronic address: anna.beronius@itm.su.se.
authors.forename: Anna
authors.initials: A
authors.lastname: Beronius
authors.affiliation: Institute of Environmental Medicine, Karolinska Institutet, PO Box 210, 171 77 Stockholm, Sweden.
authors.forename: Annika
authors.initials: A
authors.lastname: Hanberg
authors.affiliation: Institute of Environmental Medicine, Karolinska Institutet, PO Box 210, 171 77 Stockholm, Sweden.
authors.forename: Johanna
authors.initials: J
authors.lastname: Zilliacus
authors.affiliation: Department of Applied Environmental Science, Stockholm University, 106 91 Stockholm, Sweden.
authors.forename: Christina
authors.initials: C
authors.lastname: Rudén
mesh_terms: D000818:Animals; D003657:Decision Making; D052244:Endocrine Disruptors / Q000633:toxicity*; D033161:Government Regulation; D006801:Humans; D012107:Research Design; D018570:Risk Assessment / Q000331:legislation & jurisprudence
chemical_list: D052244:Endocrine Disruptors