title: Isolated Microtia With Anterior Hemispheric Polymicrogyria.
abstract: We report on a male infant who presented with neonatal clonic seizure and was found to have isolated left-sided microtia on clinical examination. Magnetic resonance imaging (MRI) of the brain revealed extensive polymicrogyria over the bilateral perisylvian and frontal cortex. He had no other associated anomaly on physical examination, genetics, metabolic, and radio imaging studies. The study of the data collected from the Italian Birth Defect Registry reported the incidence of microtia-anotia as 1.46/10 000. Microtia-anotia can also be found in association with other anomalies that characterizes oculo-auriculo-vertebral spectrum. Although oculo-auriculo-vertebral spectrum has been associated with various cerebral malformations, isolated microtia usually does not have such association. We could not find any report of polymicrogyria in a case of isolated microtia.
authors.affiliation: Department of Pediatrics, Midland Regional Hospital, Mullingar, Ireland drbirendrarai@gmail.com.
authors.forename: Birendra
authors.initials: B
authors.lastname: Rai
authors.affiliation: Bankura Sammilani Medical College, Bankura, India.
authors.forename: Rudra
authors.initials: R
authors.lastname: Gouda
authors.affiliation: Department of Pediatrics, Midland Regional Hospital, Mullingar, Ireland.
authors.forename: Sudha
authors.initials: S
authors.lastname: Moka
authors.affiliation: Department of Pediatrics, Midland Regional Hospital, Mullingar, Ireland.
authors.forename: Liz Elizabeth
authors.initials: LE
authors.lastname: Dunbar
mesh_terms: D002675:Child, Preschool; D065817:Congenital Microtia / Q000150:complications*; D007839:Functional Laterality; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D065706:Polymicrogyria / Q000150:complications* / Q000175:diagnosis
keywords: isolated microtia anotia; oculo-auriculo-vertebral spectrum; polymicrogyria