title: Management of Complications of End-Stage Liver Disease in the Intensive Care Unit.
abstract: The management of critically ill patients with end-stage liver disease can be challenging due to the vulnerability of this population and the wide-ranging complications of the disease. This review proposes an approach based on the major organ systems affected, to provide a framework for managing the most common complications. Although considerable practice variation exists, a focus on the evidence behind the most common practices will ensure the development of the optimal skillset to appropriately manage this disease.
authors.affiliation: Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA dellavolpejd@upmc.edu.
authors.forename: Jeffrey D
authors.initials: JD
authors.lastname: DellaVolpe
authors.affiliation: Department of Pharmacy & Therapeutics, Transplant Intensive Care Unit, UPMC Presbyterian Shadyside, Pittsburgh, PA, USA.
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Garavaglia
authors.affiliation: Department of Critical Care Medicine, Director Multidisciplinary Acute Care Research Organization, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
authors.forename: David T
authors.initials: DT
authors.lastname: Huang
mesh_terms: D002318:Cardiovascular Diseases / Q000150:complications / Q000628:therapy; D003141:Communicable Diseases / Q000150:complications / Q000628:therapy; D003422:Critical Care / Q000379:methods*; D058625:End Stage Liver Disease / Q000150:complications*; D005767:Gastrointestinal Diseases / Q000150:complications / Q000628:therapy; D006801:Humans; D007362:Intensive Care Units; D007674:Kidney Diseases / Q000150:complications / Q000628:therapy; D008171:Lung Diseases / Q000150:complications / Q000628:therapy; D009422:Nervous System Diseases / Q000150:complications / Q000628:therapy
keywords: End-stage liver disease; hepatic encephalopathy; hepatopulmonary syndrome; hepatorenal syndrome; spontaneous bacterial peritonitis; variceal bleed