title: Comparative evaluation of root surface morphology after planing and root conditioning with tetracycline hydrochloride--an in vitro SEM study.
abstract: OBJECTIVE
  Tetracycline hydrochloride has been shown to produce changes on periodontally involved root surfaces that can potentially enhance periodontal regeneration. This in vitro study was carried out to compare the root surface changes after scaling and root planing alone, and scaling and root planing followed by application of 100 mg/ml tetracycline hydrochloride under the Scanning Electron Microscope.
  
  
  METHODS
  Fifteen periodontally compromised freshly extracted single-rooted teeth were thoroughly cleaned. The teeth were then sectioned into thirty blocks and divided into two groups. Group I (control) consisted of teeth which received scaling and and root planing alone and Group II received scaling and root planing followed by application of 100 mg/ml tetracycline hydrochloride under the Scanning Electron Microscope.
  
  
  RESULTS
  Tetracycline hydrochloride solution showed statistically highly significant removal of smear layer at 100 mg/ml solution (p < 0.001) and enlargement of dentinal tubule diameter (1.46 microm).
  
  
  CONCLUSIONS
  It can be concluded that tetracycline hydrochloride at concentration 100 mg/ml effectively removes the smear layer and enlarges the dentinal tubules.
authors.forename: Mudit
authors.initials: M
authors.lastname: Mittal
authors.forename: Pallavi
authors.initials: P
authors.lastname: Vashisth
authors.forename: K K
authors.initials: KK
authors.lastname: Chaubey
authors.forename: Swati
authors.initials: S
authors.lastname: Dwivedi
authors.forename: Satyaki
authors.initials: S
authors.lastname: Arora
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D055113:Chronic Periodontitis / Q000473:pathology / Q000628:therapy*; D012534:Dental Scaling / Q000379:methods; D003804:Dentin / Q000187:drug effects / Q000648:ultrastructure; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008855:Microscopy, Electron, Scanning; D016745:Root Planing / Q000379:methods*; D016369:Smear Layer; D013752:Tetracycline / Q000627:therapeutic use*; D014092:Tooth Root / Q000187:drug effects / Q000648:ultrastructure*
chemical_list: D000900:Anti-Bacterial Agents; D013752:Tetracycline