title: Cytomegalovirus retinitis diagnosed after completion of chemotherapy for acute lymphoblastic leukemia in an adolescent.
abstract: Although cytomegalovirus (CMV) retinitis is usually diagnosed in allogeneic hematopoietic cell transplantation recipients among patients with hematologic and oncologic disease, it can also occur in acute leukemia patients who have not received hematopoietic cell transplantation. However, CMV retinitis diagnosed after completion of chemotherapy for acute leukemia has not previously been reported. A 17-year-old boy was diagnosed with CMV retinitis 3 months after completion of chemotherapy for acute lymphoblastic leukemia, and his retinitis was assumed to be caused by a delayed immune reconstitution after chemotherapy. The patient was treated with intravenous and intravitreous ganciclovir therapy, and subsequently underwent surgery for retinal detachment.
authors.affiliation: *Department of Pediatrics, Seoul St. Mary's Hospital, Banpo-daero, Seocho-gu †Vaccine Bio Research Institute ‡Catholic Blood and Marrow Transplantation Center §Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
authors.forename: Seung Beom
authors.initials: SB
authors.lastname: Han
authors.forename: Jin Hee
authors.initials: JH
authors.lastname: Lee
authors.forename: Jae Wook
authors.initials: JW
authors.lastname: Lee
authors.forename: Nack-Gyun
authors.initials: NG
authors.lastname: Chung
authors.forename: Bin
authors.initials: B
authors.lastname: Cho
authors.forename: Jin Han
authors.initials: JH
authors.lastname: Kang
authors.forename: Hack-Ki
authors.initials: HK
authors.lastname: Kim
authors.forename: Jin Hae
authors.initials: JH
authors.lastname: Lee
authors.forename: Won Ki
authors.initials: WK
authors.lastname: Lee
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D000998:Antiviral Agents / Q000627:therapeutic use; D003587:Cytomegalovirus / Q000472:pathogenicity; D017726:Cytomegalovirus Retinitis / Q000139:chemically induced* / Q000188:drug therapy / Q000821:virology; D015774:Ganciclovir / Q000627:therapeutic use; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000188:drug therapy* / Q000821:virology; D011379:Prognosis
chemical_list: D000998:Antiviral Agents; D015774:Ganciclovir