title: Novel Immunotherapies for B-Cell Lymphomas and Leukemias.
abstract: Current immunotherapeutic agents under investigation have the potential to significantly expand our ability to effectively treat B-cell malignancies. New disease targets, novel strategies to deliver therapy, and advanced agents that work to manipulate the immune system are a few of the ways immunotherapy has quickly evolved. Novel targeted and immune-modifying therapies may demonstrate early potential but unique toxicities and other limitations, such as difficulties in administration, must also be acknowledged. This review provides a comprehensive assessment of the current immunotherapies under investigation against B-cell malignancies.
authors.affiliation: Department of Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.
authors.forename: Michael T
authors.initials: MT
authors.lastname: Tees
authors.forename: Lubomir
authors.initials: L
authors.lastname: Sokol
mesh_terms: D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D007938:Leukemia / Q000276:immunology / Q000628:therapy*; D016393:Lymphoma, B-Cell / Q000276:immunology / Q000628:therapy*; D058990:Molecular Targeted Therapy