title: Norovirus-associated encephalitis in a previously healthy 2-year-old girl.
abstract: We describe the case of 2-year-old girl with encephalitis associated with norovirus infection. The viral genome was detected in cerebrospinal fluid and stool by reverse transcription polymerase chain reaction. This is the first time in Spain and the second worldwide that the genome of norovirus from the stool sample and 2 cerebrospinal fluid samples were genetically characterized and matched.
authors.affiliation: From the *Instituto de Salud Carlos III, Majadahonda, Madrid; †Hospital Universitario Virgen del Rocío/IBIS/CSIC/Universidad de Sevilla, Seville; ‡Hospital Sant Joan de Déu; and §Department of Pediatrics, Barcelona University, Barcelona, Spain.
authors.forename: Alicia
authors.initials: A
authors.lastname: Sánchez-Fauquier
authors.forename: Veronica
authors.initials: V
authors.lastname: González-Galán
authors.forename: Sandra
authors.initials: S
authors.lastname: Arroyo
authors.forename: Diana
authors.initials: D
authors.lastname: Rodà
authors.forename: Martí
authors.initials: M
authors.lastname: Pons
authors.forename: Juan-Jose
authors.initials: JJ
authors.lastname: García
mesh_terms: D017250:Caliciviridae Infections / Q000175:diagnosis* / Q000473:pathology* / Q000821:virology; D002555:Cerebrospinal Fluid / Q000821:virology; D002675:Child, Preschool; D018792:Encephalitis, Viral / Q000175:diagnosis* / Q000473:pathology* / Q000821:virology; D005243:Feces / Q000821:virology; D005260:Female; D006801:Humans; D029322:Norovirus / Q000302:isolation & purification*; D012367:RNA, Viral / Q000235:genetics / Q000302:isolation & purification; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013030:Spain
chemical_list: D012367:RNA, Viral