title: Endoscopic management of pancreatic pseudocysts and necrosis.
abstract: Over the last several years, there have been refinements in the understanding and nomenclature regarding the natural history of acute pancreatitis. Patients with acute pancreatitis frequently develop acute pancreatic collections that, over time, may evolve into pancreatic pseudocysts or walled-off necrosis. Endoscopic management of these local complications of acute pancreatitis continues to evolve. Treatment strategies range from simple drainage of liquefied contents to repeated direct endoscopic necrosectomy of a complex necrotic collection. In patients with chronic pancreatitis, pancreatic pseudocysts may arise as a consequence of pancreatic ductal obstruction that then leads to pancreatic ductal disruption. In this review, we focus on the indications, techniques and outcomes for endoscopic therapy of pancreatic pseudocysts and walled-off necrosis.
authors.affiliation: Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
authors.forename: Ryan
authors.initials: R
authors.lastname: Law
authors.forename: Todd H
authors.initials: TH
authors.lastname: Baron
mesh_terms: D019468:Disease Management; D004322:Drainage / Q000379:methods; D004724:Endoscopy / Q000379:methods*; D006801:Humans; D009336:Necrosis / Q000601:surgery; D010179:Pancreas / Q000473:pathology* / Q000601:surgery*; D010192:Pancreatic Pseudocyst / Q000601:surgery*; D015607:Stents; D016896:Treatment Outcome
keywords: acute pancreatitis; drainage/methods; endoscopic therapy; minimally invasive; pancreatic necrosis/therapy; pancreatitis/complications; therapeutic irrigation