title: [Retrospective analysis of 50 thymic epithelial tumors in Rennes university hospital].
abstract: BACKGROUND
  Thymic epithelial tumors (TET), including thymomas and thymic carcinomas, are rare and characterized by very different evolutionary patterns depending on histology and invasion stage. The therapeutic management is not well defined but is a subject of increasing interest. The descriptive and analytic objectives of this retrospective monocentric study were to analyze the clinical characteristics of patients with TET, and to assess the management of these tumors in our centre.
  
  
  METHODS
  Adult patients with TET managed in the Rennes university hospital in the period 2000-2011 were selected via the pathology department. Their clinical and pathological features and survival were analyzed retrospectively.
  
  
  RESULTS
  Fifty TET were retrieved (46 thymomas and 4 thymic carcinomas). Their clinical and histological features and their invasion stages were concordant with published studies. Their diagnostic and therapeutic managements were also in accordance with current guidelines. In univariate analysis, myasthenia and surgery were associated with better survival rates.
  
  
  CONCLUSIONS
  Management of TET in Rennes university hospital is in accordance with guidelines.
authors.affiliation: Service de pneumologie, hôpital Pontchaillou, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35033 Rennes, France. Electronic address: mallorie.kerjouan@chu-rennes.fr.
authors.forename: M
authors.initials: M
authors.lastname: Kerjouan
authors.affiliation: Service de pneumologie, hôpital Pontchaillou, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35033 Rennes, France.
authors.forename: R
authors.initials: R
authors.lastname: Corre
authors.affiliation: Service de pneumologie, hôpital Pontchaillou, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35033 Rennes, France.
authors.forename: H
authors.initials: H
authors.lastname: Léna
authors.affiliation: Service d'anatomie et cytologie pathologiques, hôpital Pontchaillou, 2, rue Henri-Le-Guilloux, 35033 Rennes, France.
authors.forename: N
authors.initials: N
authors.lastname: Choukeir
authors.affiliation: Service d'anatomie et cytologie pathologiques, hôpital Pontchaillou, 2, rue Henri-Le-Guilloux, 35033 Rennes, France.
authors.forename: D C
authors.initials: DC
authors.lastname: Chiforeanu
authors.affiliation: Service de chirurgie thoracique et cardiovasculaire, hôpital Pontchaillou, 2, rue Henri-Le-Guilloux, 35033 Rennes, France.
authors.forename: B
authors.initials: B
authors.lastname: de Latour
authors.affiliation: Service de chirurgie thoracique et cardiovasculaire, hôpital Pontchaillou, 2, rue Henri-Le-Guilloux, 35033 Rennes, France.
authors.forename: J-P
authors.initials: JP
authors.lastname: Verhoye
authors.affiliation: Service de pneumologie, hôpital Pontchaillou, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35033 Rennes, France.
authors.forename: B
authors.initials: B
authors.lastname: Desrues
authors.affiliation: Service de pneumologie, hôpital Pontchaillou, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35033 Rennes, France; IRSET, UMR 1085, université de Rennes 1, 35043 Rennes, France.
authors.forename: S
authors.initials: S
authors.lastname: Jouneau
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005602:France; D006785:Hospitals, University; D006801:Humans; D008297:Male; D008875:Middle Aged; D009375:Neoplasms, Glandular and Epithelial / Q000175:diagnosis* / Q000628:therapy*; D012189:Retrospective Studies; D013953:Thymus Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D055815:Young Adult
keywords: Carcinomes thymiques; Chirurgie; Radiotherapy; Radiothérapie; Surgery; Thymic carcinomas; Thymic epithelial tumors; Thymomas; Thymomes; Tumeurs épithéliales thymiques