title: Experimental verification of depolarization effects in bioelectrical impedance measurement.
abstract: The electrode polarization effects on bioelectrical impedance measurement at low-frequency cannot be ignored. In this paper, the bioelectrical data of mice livers are measured to specify the polarization effects on the bio-impedance measurement data. We firstly introduce the measurement system and methodology. Using the depolarization method, the corrected results are obtained. Besides, the specific effects of electrode polarization on bio-impedance measurement results are investigated using comparative analysis of the previous and posterior correction results from dielectric spectroscopy, Cole-Cole plot, conductivity and spectroscopy of dissipation tangent. Experimental results show that electrode polarization has a significant influence on the characteristic parameters of mouse liver tissues. To be specific, we see a low-frequency limit resistance R0 increase by 19.29%, a reactance peak XP increase by 8.50%, a low-frequency limit conductivity Kl decrease by 17.65% and a dissipation peak tangent decrease by 160%.
authors.affiliation: College of Electronic Information and Automation, Tianjin University of Science and Technology, Tianjin 300222, China.
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Chen
authors.affiliation: College of Electronic Information and Automation, Tianjin University of Science and Technology, Tianjin 300222, China.
authors.forename: Xinqiang
authors.initials: X
authors.lastname: Lv
authors.affiliation: College of Electronic Information and Automation, Tianjin University of Science and Technology, Tianjin 300222, China.
authors.forename: Meng
authors.initials: M
authors.lastname: Du
mesh_terms: D000818:Animals; D016477:Artifacts; D003198:Computer Simulation; D058266:Dielectric Spectroscopy / Q000295:instrumentation* / Q000379:methods*; D017097:Electric Impedance; D004566:Electrodes; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005240:Feasibility Studies; D008099:Liver / Q000502:physiology*; D051379:Mice; D008954:Models, Biological; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
keywords: Electrode polarization; depolarization correction; impedance measurement; low-frequency