title: Control of cardiovascular risk factors in revascularized patients with diabetes: a subanalysis of the ICP-Bypass study.
abstract: OBJECTIVE
  Patients with type 2 diabetes and revascularized coronary disease are a group with very high cardiovascular risk that has been rarely studied. This ICP-Bypass substudy analyzes the clinical characteristics and risk factor control of these patients.
  
  
  METHODS
  The analysis selected patients with type 2 diabetes who had participated in an earlier multicenter, observational, cross-sectional study (ICP-Bypass) conducted in 2293 patients > 18 years of age who had undergone coronary surgery or percutaneous coronary intervention. Demographic and therapeutic variables, as well as clinical and analytical parameters, were collected and comparatively analyzed.
  
  
  RESULTS
  The mean age (standard deviation) of the 771 diabetic patients included in the analysis was 67.7 (9.6) years (71.4% men; mean time since revascularization, 3.5 years). Most (57.8%) were receiving treatment with oral hypoglycemics alone, whereas 30.4% were receiving insulin alone or in combination. The mean glycohemoglobin figure was 7.1% (in 70%,<7.5%); 74.8% had been diagnosed with dyslipidemia. Mean low-density lipoprotein cholesterol was 93.5 mg/dL (in 73%, > 70 mg/dL). Among these patients, 93.6% were receiving statins and 18.7% a statin combined with ezetimib. A total of 78.1% had been diagnosed with hypertension; systolic/diastolic blood pressure was < 130/80 mmHg in 52% and < 140/90 mmHg in 93%.
  
  
  CONCLUSIONS
  Cardiovascular risk and prevention may be improved in revascularized diabetic patients in Spain through further control of risk factors, particularly dyslipidemia. Patients with glycohemoglobin > 7.5% should be individually assessed in terms of glycemic targets.
authors.affiliation: Servicio de Cardiología, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, A Coruña, Spain. Electronic address: pilarmazon@yahoo.es.
authors.forename: Pilar
authors.initials: P
authors.lastname: Mazón-Ramos
authors.affiliation: Servicio de Cardiología, Hospital Universitario de San Juan, San Juan de Alicante, Alicante, Spain.
authors.forename: Alberto
authors.initials: A
authors.lastname: Cordero
authors.affiliation: Servicio de Cardiología, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, A Coruña, Spain.
authors.forename: José Ramón
authors.initials: JR
authors.lastname: González-Juanatey
authors.affiliation: Servicio de Cardiología, Hospital Universitario de San Juan, San Juan de Alicante, Alicante, Spain.
authors.forename: Vicente
authors.initials: V
authors.lastname: Bertomeu Martínez
authors.affiliation: Servicio de Endocrinología, Hospital Central de Asturias, Oviedo, Asturias, Spain.
authors.forename: Elías
authors.initials: E
authors.lastname: Delgado
authors.affiliation: Departamento Médico, Merck Sharp & Dohme (MSD), Spain.
authors.forename: Gustavo
authors.initials: G
authors.lastname: Vitale
authors.affiliation: Departamento Médico, Merck Sharp & Dohme (MSD), Spain.
authors.forename: Silvia
authors.initials: S
authors.lastname: Fernández-Anaya
mesh_terms: D000368:Aged; D050197:Atherosclerosis / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D001786:Blood Glucose / Q000378:metabolism; D008078:Cholesterol, LDL / Q000378:metabolism; D003324:Coronary Artery Disease / Q000150:complications / Q000453:epidemiology / Q000601:surgery*; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications*; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D015994:Incidence; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000379:methods*; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology
chemical_list: D001786:Blood Glucose; D008078:Cholesterol, LDL; D006442:Glycated Hemoglobin; D000960:Hypolipidemic Agents
keywords: Aterosclerosis; Atherosclerosis; Coronary disease; Diabetes mellitus; Enfermedad coronaria; Revascularización; Revascularization