title: Beta blocker eye drops for treatment of acute migraine.
abstract: We report seven cases of successful treatment of acute migraine symptoms using beta blocker eye drops. The literature on beta blockers for acute migraine is reviewed. Oral beta blocker medication is not effective for acute migraine treatment. This is likely due to a relatively slow rate of achieving therapeutic plasma levels when taken orally. Topical beta blocker eye drops achieve therapeutic plasma levels within minutes of ocular administration which may explain their apparent effectiveness in relief of acute migraine symptoms.
authors.forename: Carl V
authors.initials: CV
authors.lastname: Migliazzo
authors.forename: John C
authors.initials: JC
authors.lastname: Hagan
mesh_terms: D000208:Acute Disease; D060433:Administration, Ophthalmic; D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage*; D000328:Adult; D000368:Aged; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007322:Instillation, Drug; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy*; D009883:Ophthalmic Solutions
chemical_list: D000319:Adrenergic beta-Antagonists; D009883:Ophthalmic Solutions