title: Some findings in transgalactosylations employing modified donor substrates.
abstract: The scope of transgalactosylation with β-galactosidase (bovine testis) was studied employing a series of modified donor substrates based on p-nitrophenyl β-D-galactopyranoside and as uniform acceptor allyl 2-N-acetamido-2-deoxy-α-D-galactopyranoside. Structurally diverse donor molecules were recognized by the enzyme and led to novel disaccharide components, yet an excessive structural distortion was not accepted.
authors.affiliation: University of Hamburg, Faculty of Science, Department of Chemistry, Martin-Luther-King-Platz 6, D-20146 Hamburg, Germany.
authors.forename: Lars
authors.initials: L
authors.lastname: Kröger
authors.affiliation: University of Hamburg, Faculty of Science, Department of Chemistry, Martin-Luther-King-Platz 6, D-20146 Hamburg, Germany. Electronic address: thiem@chemie.uni-hamburg.de.
authors.forename: Joachim
authors.initials: J
authors.lastname: Thiem
mesh_terms: D000818:Animals; D002417:Cattle; D005690:Galactose / Q000378:metabolism*; D006031:Glycosylation; D008297:Male; D013737:Testis / Q000201:enzymology; D001616:beta-Galactosidase / Q000378:metabolism
chemical_list: D001616:beta-Galactosidase; D005690:Galactose
keywords: Modified T-antigen components; Modified p-nitrophenyl glycopyranosides; Transgalactosylation; β-Galactosidase (bovine testis)