title: The problems of urinary tract infections with Candida spp. aetiology in women.
abstract: Urinary tract infections (UTIs) in women are a growing clinical concern. The most frequent risk factors of UTIs with fungal aetiology in women are: antibiotic therapy (especially broad-spectrum antibiotics), immunosuppressive therapy, diabetes, malnutrition, pregnancy, and frequent intercourse. The aim of the study was to analyse urinary tract infections with Candida spp. aetiology in women hospitalised at the Clinical Hospital in Poznań, Poland, between 2009 and 2011. The investigations revealed that as many as 71% of positive urine cultures with Candida fungi came from women. The following fungi were most frequently isolated from the patients under analysis: C. albicans (47%), C. glabrata (31%), C. tropicalis (6%), C. krusei (3%). In order to diagnose a UTI the diagnosis cannot be based on a single result of a urine culture. Due to the small number of antifungal drugs and high costs of treatment, antifungal drugs should be applied with due consideration and care.
authors.affiliation: Central Microbiological Laboratory, H. Święcicki Clinical Hospital, University of Medical Sciences, Poznań, Poland.
authors.forename: Hanna
authors.initials: H
authors.lastname: Tomczak
authors.affiliation: Clinical Pharmacy and Biopharmacy Department and Unit, University of Medical Sciences, Poznań, Poland.
authors.forename: Edyta
authors.initials: E
authors.lastname: Szałek
authors.affiliation: Clinical Pharmacy and Biopharmacy Department and Unit, University of Medical Sciences, Poznań, Poland.
authors.forename: Edmund
authors.initials: E
authors.lastname: Grześkowiak
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D015984:Causality; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D011044:Poland / Q000453:epidemiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D014556:Urine / Q000382:microbiology; D016387:Women's Health
chemical_list: D000935:Antifungal Agents