title: Association of antimüllerian hormone levels with menstrual-cycle type and dysmenorrhea in young asymptomatic women.
abstract: OBJECTIVE
  To examine the association between antimüllerian hormone (AMH) levels and menstrual-cycle and lifestyle characteristics among young Japanese women.
  
  
  METHODS
  Cross-sectional study.
  
  
  METHODS
  University.
  
  
  METHODS
  Female students aged 20-22 years (n=65) who had never used oral contraceptives.
  
  
  METHODS
  Participants completed a questionnaire on reproductive and lifestyle characteristics, and kept a menstrual-cycle diary for 5 consecutive months. Serum AMH was measured once during the study period.
  
  
  METHODS
  Serum AMH concentration.
  
  
  RESULTS
  Compared with women with very mild menstrual pain, serum AMH concentration was 49.6% (95% CI 6.5%-72.8%) lower among women with severe menstrual pain. Higher AMH concentration was associated with irregular menstrual cycles. Even after adjusting for menstrual-cycle regularity and its interaction, more-severe menstrual pain was associated with significantly lower AMH concentration.
  
  
  CONCLUSIONS
  Circulating AMH concentration was significantly lower among young Japanese women who had more-severe menstrual pain. Underlying physiological mechanisms need to be addressed in future studies.
authors.affiliation: Department of Human Ecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; Department of Anthropology, University of Washington, Seattle, Washington. Electronic address: moe@humeco.m.u-tokyo.ac.jp.
authors.forename: Shoko
authors.initials: S
authors.lastname: Konishi
authors.affiliation: Department of Environment Systems, Graduate School of Frontier Science, The University of Tokyo, Tokyo, Japan.
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Nishihama
authors.affiliation: Department of Environment Systems, Graduate School of Frontier Science, The University of Tokyo, Tokyo, Japan; School of Allied Health Sciences, Kitasato University, Sagamihara, Japan.
authors.forename: Ayaka
authors.initials: A
authors.lastname: Iida
authors.affiliation: Department of Environment Systems, Graduate School of Frontier Science, The University of Tokyo, Tokyo, Japan.
authors.forename: Jun
authors.initials: J
authors.lastname: Yoshinaga
authors.affiliation: Faculty of Nursing, Tokyo Healthcare University, Tokyo, Japan.
authors.forename: Hideki
authors.initials: H
authors.lastname: Imai
mesh_terms: D054304:Anti-Mullerian Hormone / Q000097:blood*; D058070:Asymptomatic Diseases; D015415:Biomarkers / Q000097:blood; D004412:Dysmenorrhea / Q000097:blood* / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008597:Menstrual Cycle / Q000097:blood*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D055815:Young Adult
chemical_list: D015415:Biomarkers; D054304:Anti-Mullerian Hormone
keywords: Antimüllerian hormone; menstrual pain; menstrual-cycle regularity; young women