title: Study of parameters for evaluating flow reduction with stents in a sidewall aneurysm phantom model.
abstract: The effect of stent design parameters such as porosity, pore density, number of strands, and strut angle to the artery were studied in vitro using particle image velocimetry (PIV). Five mesh stents were implanted into a sidewall aneurysm model. The flow features in a sidewall aneurysm silicone phantom model were investigated at a Reynolds number of 300. It was found that the lowest porosity stent had the best value for velocity and vorticity reduction in an aneurysm pocket. The stent with higher pore density had a tendency to decrease the mean and maximum velocities, but it was not superior to the effects of porosity. In addition, investigation of the evaluation system confirmed that higher stent strut angles to the parent artery had a tendency to lower mean velocity, as shown by PIV and CFD. However, this effect was relatively smaller compared to porosity and pore density. Our evaluation system suggested the best combinations of parameters for the development of an ideal stent would be lower porosity, higher pore density, and higher strut angle. The results obtained in this study indicated that our evaluation system could be useful for various purposes related to evaluation of endovascular interventional devices.
authors.affiliation: Division of Biomedical Engineering, Chonbuk National University, 567 Baekje-daero, Deokjin-gu, Jeonju-si, Jeonbuk 561-756, Republic of Korea.
authors.forename: Chang Ho
authors.initials: CH
authors.lastname: Yu
authors.affiliation: Division of Biomedical Engineering, Chonbuk National University, 567 Baekje-daero, Deokjin-gu, Jeonju-si, Jeonbuk 561-756, Republic of Korea.
authors.forename: Tae Kyu
authors.initials: TK
authors.lastname: Kwon
mesh_terms: D032701:Biomimetics / Q000295:instrumentation; D001783:Blood Flow Velocity; D001794:Blood Pressure; D001807:Blood Vessel Prosthesis; D002560:Cerebrovascular Circulation; D017076:Computer-Aided Design; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D002532:Intracranial Aneurysm / Q000503:physiopathology* / Q000628:therapy*; D017078:Laser-Doppler Flowmetry; D019047:Phantoms, Imaging; D033081:Shear Strength; D015607:Stents; D016896:Treatment Outcome
keywords: Particle Image Velocimetry (PIV); pore density; porosity; sidewall aneurysm; stent