title: The kidney research national dialogue: gearing up to move forward.
abstract: The National Institute of Diabetes and Digestive and Kidney Diseases-supported Kidney Research National Dialogue asked the scientific community to formulate and prioritize research objectives that would improve our understanding of kidney function and disease; >1600 participants from >30 countries posted >300 ideas and >500 comments covering all areas of kidney research. Smaller groups of investigators interrogated the postings and published a series of commentaries in CJASN. Additional review of the entire series identified six cross-cutting themes: (1) increase training and team science opportunities to maintain/expand the nephrology workforce, (2) develop novel technologies to assess kidney function, (3) promote human discovery research to better understand normal and diseased kidney function, (4) establish integrative models of kidney function to inform diagnostic and treatment strategies, (5) promote interventional studies that incorporate more responsive outcomes and improved trial designs, and (6) foster translation from clinical investigation to community implementation. Together, these cross-cutting themes provide a research plan to better understand normal kidney biology and improve the prevention, diagnosis, and treatment of kidney disease, and as such, they will inform future research efforts supported by the National Institute of Diabetes and Digestive and Kidney Diseases through workshops and initiatives.
authors.affiliation: Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.
authors.forename: Joseph V
authors.initials: JV
authors.lastname: Bonventre
authors.affiliation: Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.
authors.forename: L Ebony
authors.initials: LE
authors.lastname: Boulware
authors.affiliation: Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.
authors.forename: Laura M
authors.initials: LM
authors.lastname: Dember
authors.affiliation: Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.
authors.forename: Barry I
authors.initials: BI
authors.lastname: Freedman
authors.affiliation: Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.
authors.forename: Susan L
authors.initials: SL
authors.lastname: Furth
authors.affiliation: Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.
authors.forename: Lawrence B
authors.initials: LB
authors.lastname: Holzman
authors.affiliation: Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.
authors.forename: Christian J
authors.initials: CJ
authors.lastname: Ketchum
authors.affiliation: Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.
authors.forename: Melissa H
authors.initials: MH
authors.lastname: Little
authors.affiliation: Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.
authors.forename: Rajnish
authors.initials: R
authors.lastname: Mehrotra
authors.affiliation: Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.
authors.forename: Sharon M
authors.initials: SM
authors.lastname: Moe
authors.affiliation: Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.
authors.forename: Jeff M
authors.initials: JM
authors.lastname: Sands
authors.affiliation: Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.
authors.forename: John R
authors.initials: JR
authors.lastname: Sedor
authors.affiliation: Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.
authors.forename: Stefan
authors.initials: S
authors.lastname: Somlo
authors.affiliation: Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.
authors.forename: Robert A
authors.initials: RA
authors.lastname: Star
authors.affiliation: Due to the number of contributing authors, the affiliations are provided in the Supplemental Material. Ryssikok@niddk.nih.gov.
authors.forename: Krystyna E
authors.initials: KE
authors.lastname: Rys-Sikora
mesh_terms: D000818:Animals; D035843:Biomedical Research / Q000193:education / Q000639:trends*; D002321:Career Choice; D003299:Cooperative Behavior; D004059:Diffusion of Innovation; D004501:Education, Medical / Q000639:trends; D006292:Health Priorities / Q000639:trends; D006801:Humans; D033183:Interdisciplinary Communication; D007391:International Cooperation; D007674:Kidney Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D054586:National Institute of Diabetes and Digestive and Kidney Diseases (U.S.); D009398:Nephrology / Q000193:education / Q000639:trends*; D011379:Prognosis; D012307:Risk Factors; D014481:United States
keywords: AKI; bioinformatics; biomarkers; systems medicine; training