title: Management of hereditary angioedema in pregnant women: a review.
abstract: two are due to C1 inhibitor (C1-INH) deficiency (C1-INH-HAE types I and II) and one is characterized by normal C1-INH (nC1-INH-HAE). The management of pregnancy in patients with HAE is often a clinical challenge owing to potential worsening of the disease in relation to the physiological increase in estrogens and the limited treatment options. This review addresses the potential influence of pregnancy on the clinical severity of hereditary angioedema and the management of this disease during pregnancy with currently available treatments.
authors.affiliation: Hospital La Paz Institute for Health Research, (IdiPaz), Madrid, Spain ; Biomedical Research Network on Rare Diseases-U754 (CIBERER), Madrid, Spain.
authors.forename: Teresa
authors.initials: T
authors.lastname: Caballero
authors.affiliation: Hospital La Paz Institute for Health Research, (IdiPaz), Madrid, Spain.
authors.forename: Julio
authors.initials: J
authors.lastname: Canabal
authors.affiliation: Hospital La Paz Institute for Health Research, (IdiPaz), Madrid, Spain.
authors.forename: Daniela
authors.initials: D
authors.lastname: Rivero-Paparoni
authors.affiliation: Hospital La Paz Institute for Health Research, (IdiPaz), Madrid, Spain.
authors.forename: Rosario
authors.initials: R
authors.lastname: Cabañas
keywords: C1 inhibitor concentrate; female; hereditary angioedema; pregnancy; tranexamic acid; treatment