title: Short-term outcomes after hospital discharge in patients admitted with heart failure in Abeokuta, Nigeria: data from the Abeokuta Heart Failure Registry.
abstract: BACKGROUND
  Compared to other regions of the world, there is a paucity of data on the short-term outcome of acute heart failure (AHF) in Africa's most populous country, Nigeria. We examined the six-month outcomes (including case fatalities) in 285 of 309 AHF subjects admitted with HF to a tertiary hospital in Abeokuta, Nigeria.
  
  
  METHODS
  The study cohort of 285 subjects comprised 150 men (52.6%) and 135 women (47.4%) with a mean age of 56.3 ± 15.6 years and the majority in NYHA class III (75%).
  
  
  RESULTS
  There were a number of differences according to the subject's gender; men being older and more likely to present with hypertensive heart disease (with greater left ventricular mass) while also having greater systolic dysfunction. Mean length of stay was 10.5 ± 5.9 days. Mean follow up was 205 days, with 23 deaths and 20 lost to follow up. At 30 days, 4.2% (95% CI: 2.4-7.3%) had died and by 180 days this had increased to 7.5% (95% CI: 4.7-11.2%); with those subjects with pericardial disease demonstrating the highest initial mortality rate. Over the same period, 13.9% of the cohort was re-admitted at least once.
  
  
  CONCLUSIONS
  The characteristics of this AHF cohort in Nigeria were different from those reported in high-income countries. Cases were relatively younger and presented with non-ischaemic aetiological risk factors for HF, especially hypertensive heart disease. Moreover, mortality and re-admission rates were relatively lower, suggesting region-specific strategies are required to improve health outcomes.
authors.affiliation: Division of Cardiology, Department of Medicine, University College Hospital, Ibadan, Nigeria; Soweto Cardiovascular Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. osogah56156@yahoo.com.
authors.forename: Okechukwu S
authors.initials: OS
authors.lastname: Ogah
authors.affiliation: NHMRC Centre of Research Excellence to Reduce, Inequality in Heart Disease Baker IDI Heart and Diabetes Institute, Melbourne, Australia.
authors.forename: Simon
authors.initials: S
authors.lastname: Stewart
authors.affiliation: Division of Cardiology, Department of Medicine, University College Hospital, Ibadan, Nigeria.
authors.forename: Ayodele O
authors.initials: AO
authors.lastname: Falase
authors.affiliation: Department of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, Nigeria.
authors.forename: Joshua O
authors.initials: JO
authors.lastname: Akinyemi
authors.affiliation: Department of Medicine, Sacred Heart Hospital, Lantoro, Abeokuta, Nigeria.
authors.forename: Gali D
authors.initials: GD
authors.lastname: Adegbite
authors.affiliation: Department of Medicine, Sacred Heart Hospital, Lantoro, Abeokuta, Nigeria.
authors.forename: Albert A
authors.initials: AA
authors.lastname: Alabi
authors.affiliation: Department of Medicine, Federal Medical Centre, Abeokuta, Nigeria.
authors.forename: Amina
authors.initials: A
authors.lastname: Durodola
authors.affiliation: Department of Medicine, Federal Medical Centre, Abeokuta, Nigeria.
authors.forename: Akinlolu A
authors.initials: AA
authors.lastname: Ajani
authors.affiliation: Hatter Institute for Cardiovascular Research in Africa and IIDMM, Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa; NHMRC Centre of Research Excellence to Reduce, Inequality in Heart Disease Baker IDI Heart and Diabetes Institute, Melbourne, Australia; Department of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, Nigeria.
authors.forename: Karen
authors.initials: K
authors.lastname: Sliwa
mesh_terms: D000208:Acute Disease; D000328:Adult; D017677:Age Distribution; D000368:Aged; D002311:Cardiomyopathy, Dilated / Q000150:complications / Q000453:epidemiology*; D015331:Cohort Studies; D005260:Female; D006333:Heart Failure / Q000453:epidemiology / Q000209:etiology / Q000401:mortality*; D006760:Hospitalization; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000453:epidemiology*; D007902:Length of Stay / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications / Q000453:epidemiology; D009549:Nigeria / Q000453:epidemiology; D017063:Outcome Assessment, Health Care; D010351:Patient Discharge; D010359:Patient Readmission / Q000706:statistics & numerical data*; D011660:Pulmonary Heart Disease / Q000150:complications / Q000453:epidemiology*; D012042:Registries