title: Pd-catalyzed asymmetric intermolecular hydroalkoxylation of allene: an entry to cyclic acetals with activating group-free and flexible anomeric control.
abstract: A ligand-directed metal-catalyzed asymmetric intermolecular hydroalkoxylation of alkoxyallene is reported. Combined with ring-closing-metathesis, this reaction offers a new atom-efficient synthetic method toward various cyclic acetals with elaborate anomeric control. Synthetic utility of the reaction was demonstrated by the atom-efficient and stereodivergent access to various mono- and disaccharides.
authors.affiliation: Department of Chemistry, Pohang University of Science and Technology , Hyoja-dong San 31, Pohang, Kyungbook, Republic of Korea 790-784.
authors.forename: Wontaeck
authors.initials: W
authors.lastname: Lim
authors.forename: Jungjoon
authors.initials: J
authors.lastname: Kim
authors.forename: Young Ho
authors.initials: YH
authors.lastname: Rhee