title: Base-promoted annulation of α-hydroxy ketones and dimethyl but-2-ynedioate: straightforward access to pyrano[4,3-a]quinolizine-1,4,6(2H)-triones and 2H-pyran-2,5(6H)-diones.
abstract: A novel and efficient cascade annulation of tertiary α-hydroxy ketones and dimethyl but-2-ynedioate is reported. The reaction, which only requires a base as the promoter, provides a straightforward access to polysubstituted pyrano[4,3-a]quinolizine-1,4,6(2H)-triones and 2H-pyran-2,5(6H)-diones under very mild reaction conditions.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, P.R. China. crqi@scut.edu.cn.
authors.forename: Haitao
authors.initials: H
authors.lastname: He
authors.forename: Chaorong
authors.initials: C
authors.lastname: Qi
authors.forename: Yanglu
authors.initials: Y
authors.lastname: Ou
authors.forename: Wenfang
authors.initials: W
authors.lastname: Xiong
authors.forename: Xiaohan
authors.initials: X
authors.lastname: Hu
authors.forename: Yanwei
authors.initials: Y
authors.lastname: Ren
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang
mesh_terms: D000480:Alkynes / Q000138:chemical synthesis* / Q000737:chemistry; D018360:Crystallography, X-Ray; D003998:Dicarboxylic Acids / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D011753:Pyrones / Q000138:chemical synthesis* / Q000737:chemistry; D011807:Quinolizines / Q000737:chemistry*
chemical_list: D000480:Alkynes; D003998:Dicarboxylic Acids; D007659:Ketones; D011753:Pyrones; D011807:Quinolizines