title: Effect of layer thickness and printing orientation on mechanical properties and dimensional accuracy of 3D printed porous samples for bone tissue engineering.
abstract: Powder-based inkjet 3D printing method is one of the most attractive solid free form techniques. It involves a sequential layering process through which 3D porous scaffolds can be directly produced from computer-generated models. 3D printed products' quality are controlled by the optimal build parameters. In this study, Calcium Sulfate based powders were used for porous scaffolds fabrication. The printed scaffolds of 0.8 mm pore size, with different layer thickness and printing orientation, were subjected to the depowdering step. The effects of four layer thicknesses and printing orientations, (parallel to X, Y and Z), on the physical and mechanical properties of printed scaffolds were investigated. It was observed that the compressive strength, toughness and Young's modulus of samples with 0.1125 and 0.125 mm layer thickness were more than others. Furthermore, the results of SEM and μCT analyses showed that samples with 0.1125 mm layer thickness printed in X direction have more dimensional accuracy and significantly close to CAD software based designs with predefined pore size, porosity and pore interconnectivity.
authors.affiliation: Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur, Malaysia.
authors.forename: Arghavan
authors.initials: A
authors.lastname: Farzadi
authors.affiliation: Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur, Malaysia; Biomaterials Center of Excellence, Amirkabir University of Technology, Tehran, Iran.
authors.forename: Mehran
authors.initials: M
authors.lastname: Solati-Hashjin
authors.affiliation: Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur, Malaysia.
authors.forename: Mitra
authors.initials: M
authors.lastname: Asadi-Eydivand
authors.affiliation: Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur, Malaysia.
authors.forename: Noor Azuan
authors.initials: NA
authors.lastname: Abu Osman
mesh_terms: D018786:Bone Substitutes / Q000737:chemistry* / Q000592:standards; D002133:Calcium Sulfate / Q000737:chemistry; D055119:Elastic Modulus; D006801:Humans; D016062:Porosity; D033362:Powder Diffraction; D066330:Printing, Three-Dimensional; D013499:Surface Properties; D023822:Tissue Engineering; D054457:Tissue Scaffolds; D014961:X-Ray Diffraction; D055114:X-Ray Microtomography
chemical_list: D018786:Bone Substitutes; D002133:Calcium Sulfate