title: Comparative care and outcomes for acute coronary syndromes in Central and Eastern European Transitional countries: A review of the literature.
abstract: OBJECTIVE
  The purpose of this review was to compare quality of care and outcomes following acute coronary syndrome (ACS) in Central and Eastern European Transitional (CEET) countries.
  
  
  METHODS
  This was a review of original ACS articles in CEET countries from PubMed, ISI Web of Science, Medline and Embase databases published in English from November 2003 to February 2014.
  
  
  RESULTS
  Seventeen manuscripts fulfilled the search criteria. Of 19 CEET countries studied, there were no published ACS management or outcome data for four countries. In-hospital mortality for patients with acute myocardial infarction (AMI) ranged from 6.3% in the Czech Republic to 15.3% in Latvia. In-hospital mortality for ST-elevation myocardial infarction (STEMI) ranged from 3.0% in Poland to 20.7% in Romania. For STEMI, primary percutaneous coronary intervention (PCI) ranged from 1.0% to over 92.0%, fibrinolytic therapy from 0.0% to 49.6%, and no reperfusion therapy from 7.0% to 63.0%.
  
  
  CONCLUSIONS
  Many CEET countries do not have published ACS care and outcomes data. Of those that do, there is evidence for substantial geographical variation in early mortality. Wide variation in emergency reperfusion strategies for STEMI suggests that acute cardiac care is likely to be modifiable and if addressed could reduce mortality from ACS in CEET countries. The collection of ACS care and outcomes data across Europe must be prioritised.
authors.affiliation: Division of Epidemiology and Biostatistics, University of Leeds, UK um10fgds@leeds.ac.uk.
authors.forename: Fraser G D
authors.initials: FG
authors.lastname: Smith
authors.affiliation: Division of Epidemiology and Biostatistics, University of Leeds, UK York Teaching Hospital, NHS Foundation Trust, UK.
authors.forename: Richard A
authors.initials: RA
authors.lastname: Brogan
authors.affiliation: Division of Epidemiology and Biostatistics, University of Leeds, UK.
authors.forename: Oras
authors.initials: O
authors.lastname: Alabas
authors.affiliation: Department of Cardiology, Aarhus University Hospital, Denmark.
authors.forename: Kristina G
authors.initials: KG
authors.lastname: Laut
authors.affiliation: Faculty of Health and Medical Sciences, University of Surrey, UK.
authors.forename: Tom
authors.initials: T
authors.lastname: Quinn
authors.affiliation: Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, University of Bologna, Italy.
authors.forename: Raffaele
authors.initials: R
authors.lastname: Bugiardini
authors.affiliation: Division of Epidemiology and Biostatistics, University of Leeds, UK York Teaching Hospital, NHS Foundation Trust, UK.
authors.forename: Chris P
authors.initials: CP
authors.lastname: Gale
mesh_terms: D054058:Acute Coronary Syndrome / Q000401:mortality / Q000628:therapy*; D005060:Europe / Q000453:epidemiology; D005061:Europe, Eastern / Q000453:epidemiology; D006801:Humans; D009203:Myocardial Infarction / Q000401:mortality / Q000628:therapy; D011787:Quality of Health Care; D016896:Treatment Outcome
keywords: Central and Eastern Europe; acute coronary syndrome; mortality; quality of care; transitional country