title: Effect of tamra bhasma (calcined copper) on ponderal and biochemical parameters.
abstract: BACKGROUND
  Tamra Bhasma (TB) and its forms like Somnathi Tamra Bhasma (STB), etc., are in vogue since centuries in Ayurveda. The present study is carried out to evaluate the effect of TB and STB in different dose levels on ponderal and biochemical parameters in wistar strain albino rats to provide scientific basis for its safety profile.
  
  
  METHODS
  TB and STB were prepared as per the classical guidelines and administered to wistar strain albino rats for 45 consecutive days. Blood was collected and rats were sacrificed on the 46(th) day. Ponderal and biochemical parameters were studied.
  
  
  RESULTS
  Results showed significant decrease in serum cholesterol, High Density Lipoprotein (HDL) cholesterol, triglycerides, total protein, and serum alkaline phosphatase levels. Comparatively, all the differences in between the groups are insignificant and no pathological changes at ponderal and biochemical levels were observed.
  
  
  CONCLUSIONS
  Based on these observations, it can be said that these formulations can be safely used in cases of hyperlipidemia.
authors.affiliation: Department of Rasa Shastra and Bhaishajya Kalpana, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India.
authors.forename: Swapnil Y
authors.initials: SY
authors.lastname: Chaudhari
authors.affiliation: Department of Rasa Shastra and Bhaishajya Kalpana, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India.
authors.forename: Galib
authors.initials: G
authors.lastname: Ruknuddin
authors.affiliation: Department of Rasa Shastra and Bhaishajya Kalpana, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India.
authors.forename: J Patgiri
authors.initials: JP
authors.lastname: Biswajyoti
authors.affiliation: Department of Rasa Shastra and Bhaishajya Kalpana, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India.
authors.forename: Prajapati Pradeep
authors.initials: PP
authors.lastname: Kumar
keywords: Bhasma; Somnathi Tamra Bhasma; Tamra Bhasma; biochemical parameters; copper; ponderal parameters