title: Advances in the surgical treatment of hilar cholangiocarcinoma.
abstract: With the improvement of perioperative management and surgical techniques as well as the accumulation of knowledge on the oncobiological behavior of bile duct carcinoma, the long-term prognosis of hilar cholangiocarcinoma has been improving. In this article, the authors review the recent developments in surgical strategies for hilar cholangiocarcinoma, focusing on diagnosis for characteristic disease extension, perioperative management to reduce postoperative morbidity and mortality, surgical techniques for extended curative resection and postoperative adjuvant therapy.
authors.affiliation: Department of Gastroenterological Surgery II, Hokkaido University Graduate School of Medicine, N-15 W-7, Sapporo 060-8638, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Tsuchikawa
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hirano
authors.forename: Keisuke
authors.initials: K
authors.lastname: Okamura
authors.forename: Joe
authors.initials: J
authors.lastname: Matsumoto
authors.forename: Eiji
authors.initials: E
authors.lastname: Tamoto
authors.forename: Soichi
authors.initials: S
authors.lastname: Murakami
authors.forename: Toru
authors.initials: T
authors.lastname: Nakamura
authors.forename: Yuma
authors.initials: Y
authors.lastname: Ebihara
authors.forename: Yo
authors.initials: Y
authors.lastname: Kurashima
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Shichinohe
mesh_terms: D001650:Bile Duct Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000601:surgery* / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D018281:Cholangiocarcinoma / Q000175:diagnosis / Q000601:surgery* / Q000628:therapy; D004322:Drainage; D004621:Embolization, Therapeutic; D006498:Hepatectomy; D006801:Humans; D008111:Liver Function Tests; D008207:Lymphatic Metastasis; D016577:Pancreaticoduodenectomy
keywords: bile duct drainage; hilar cholangiocarcinoma; percutaneous transhepatic portal embolization; perioperative management; residual liver function; superficial spreading biliary cancer; surgical strategy