title: Bilateral congenital cataract with suspected lens-induced granulomatous uveitis.
abstract: A healthy newborn baby girl presented with congenital bilateral cataract. Within a few days of presenting she also developed bilateral granulomatous uveitis, a condition generally linked in newborns to congenital infections, most frequently TORCHES syndrome (toxoplasmosis, rubella, cytomegalic inclusion disease, herpesvirus, including Epstein-Barr, syphilis). Extensive investigation did not reveal any underlying etiologic mechanism. Treatment with topical and systemic steroids did not improve the uveitis. However, bilateral lens extraction resulted in a quick resolution of the uveitis.
authors.affiliation: Department of Ophthalmology, University Hospitals Leuven, Belgium. Electronic address: stephanie.vandenbroucke@uz.leuven.be.
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Vandenbroucke
authors.affiliation: Department of Ophthalmology, University Hospitals Leuven, Belgium.
authors.forename: Beatrijs
authors.initials: B
authors.lastname: Foets
authors.affiliation: Department of Pediatrics, University Hospitals Leuven, Belgium.
authors.forename: Carine
authors.initials: C
authors.lastname: Wouters
authors.affiliation: Department of Ophthalmology, University Hospitals Leuven, Belgium.
authors.forename: Ingele
authors.initials: I
authors.lastname: Casteels
mesh_terms: D001724:Birth Weight; D002386:Cataract / Q000151:congenital*; D002387:Cataract Extraction; D005260:Female; D005865:Gestational Age; D005938:Glucocorticoids / Q000008:administration & dosage; D006099:Granuloma / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D007231:Infant, Newborn; D007905:Lens Diseases / Q000150:complications* / Q000503:physiopathology; D008775:Methylprednisolone / Q000008:administration & dosage; D014606:Uveitis, Anterior / Q000209:etiology* / Q000503:physiopathology; D014821:Vitrectomy
chemical_list: D005938:Glucocorticoids; D008775:Methylprednisolone