title: A new HCV mouse model on the block.
abstract: The investigation of virus-induced liver disease and hepatocellular carcinoma needs small animal models modeling hepatitis C virus (HCV) infection and liver disease biology. A recent study published in Cell Research reports a novel mouse model which is permissive for chronic HCV infection and shows chronic liver injury including inflammation, steatosis and fibrosis.
authors.affiliation: 1] Inserm, U1110, Strasbourg, France [2] Université de Strasbourg, Strasbourg, France.
authors.forename: Rajiv G
authors.initials: RG
authors.lastname: Tawar
authors.affiliation: 1] Inserm, U1110, Strasbourg, France [2] Université de Strasbourg, Strasbourg, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Mailly
authors.affiliation: 1] Inserm, U1110, Strasbourg, France [2] Université de Strasbourg, Strasbourg, France [3] Pôle Hépato-digestif, Institut Hospitalo-Universitaire, Strasbourg, France.
authors.forename: Thomas F
authors.initials: TF
authors.lastname: Baumert
mesh_terms: D000818:Animals; D005260:Female; D016174:Hepacivirus / Q000502:physiology*; D006526:Hepatitis C / Q000276:immunology* / Q000821:virology*; D006801:Humans; D007121:Immunocompetence; D008099:Liver / Q000473:pathology* / Q000821:virology*; D008297:Male