title: Permeation study through bacterial cellulose membrane.
abstract: Abstract: The objective of this study was to fabricate topical formulations of diclofenac diethylamine (DD) using isopropyl myristate (IPM) and isopropyl palmitate (IPP) as permeation enhancers. Franz cell and bacterial cellulose were used as analytical instrument and diffusion membrane, respectively. Permeation enhancers exhibited significant effect on the permeation characteristics of DD. It was concluded from the results that improved permeation of DD was observed when IPP was used as enhancer.
authors.forename: Chengdong
authors.initials: C
authors.lastname: Wu
authors.forename: Ghulam
authors.initials: G
authors.lastname: Murtaza
authors.forename: Muhammad Arfat
authors.initials: MA
authors.lastname: Yameen
authors.forename: Muhammad Naeem
authors.initials: MN
authors.lastname: Aamir
authors.forename: Muhammad
authors.initials: M
authors.lastname: Akhtar
authors.forename: Yuhao
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D000279:Administration, Cutaneous; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000493:pharmacokinetics*; D001419:Bacteria; D002482:Cellulose / Q000378:metabolism*; D004008:Diclofenac / Q000008:administration & dosage / Q000493:pharmacokinetics*; D005079:Excipients / Q000737:chemistry*; D008566:Membranes / Q000378:metabolism; D009226:Myristates / Q000737:chemistry; D010168:Palmitates / Q000737:chemistry; D010539:Permeability; D012869:Skin Absorption
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005079:Excipients; D009226:Myristates; D010168:Palmitates; C008205:isopropyl myristate; D004008:Diclofenac; C005060:isopropyl palmitate; D002482:Cellulose