title: Organocatalytic asymmetric strategies to carbocyclic structures by γ-alkylation-annulation sequences.
abstract: Attractive carbocyclic structures are accessed via a highly regio- and enantioselective aminocatalytic γ-addition of cyclic enals to vinyl phosphonates followed by a one-pot intramolecular Horner-Wadsworth-Emmons reaction. It is also demonstrated that nitro olefins can act as electrophiles in a similar reaction concept, providing carbocycles in equally high stereoselectivity.
authors.affiliation: Center for Catalysis, Department of Chemistry, Aarhus University, DK-8000 Aarhus C, Denmark. kaj@chem.au.dk.
authors.forename: Bjarke S
authors.initials: BS
authors.lastname: Donslund
authors.forename: Kim Søholm
authors.initials: KS
authors.lastname: Halskov
authors.forename: Lars A
authors.initials: LA
authors.lastname: Leth
authors.forename: Bruno Matos
authors.initials: BM
authors.lastname: Paz
authors.forename: Karl Anker
authors.initials: KA
authors.lastname: Jørgensen