title: Enhanced transmission of antibiotic resistance in Campylobacter jejuni biofilms by natural transformation.
abstract: Campylobacter jejuni is a leading food-borne pathogen, and its antibiotic resistance is of serious concern to public health worldwide. C. jejuni is naturally competent for DNA transformation and freely takes up foreign DNA harboring genetic information responsible for antibiotic resistance. In this study, we demonstrate that C. jejuni transfers antibiotic resistance genes more frequently in biofilms than in planktonic cells by natural transformation.
authors.affiliation: School of Public Health, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Junghee
authors.initials: J
authors.lastname: Bae
authors.affiliation: School of Public Health, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Euna
authors.initials: E
authors.lastname: Oh
authors.affiliation: School of Public Health, University of Alberta, Edmonton, Alberta, Canada bjeon@ualberta.ca.
authors.forename: Byeonghwa
authors.initials: B
authors.lastname: Jeon
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D018441:Biofilms / Q000187:drug effects* / Q000254:growth & development; D016123:Campylobacter jejuni / Q000187:drug effects / Q000235:genetics* / Q000254:growth & development; D002701:Chloramphenicol / Q000494:pharmacology; D003850:Deoxyribonuclease I / Q000494:pharmacology; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D006801:Humans; D007612:Kanamycin / Q000494:pharmacology; D010933:Plankton / Q000187:drug effects* / Q000254:growth & development; D014169:Transformation, Bacterial
chemical_list: D000900:Anti-Bacterial Agents; D007612:Kanamycin; D002701:Chloramphenicol; D003850:Deoxyribonuclease I