title: [The P300 component as a neurophysiological correlate of behavioural working memory in adolescents with attention deficit hyperactivity disorder].
abstract: BACKGROUND
  Deficit in the executive functions has been widely studied in attention deficit hyperactivity disorder (ADHD). The interest in its neurophysiological correlates has led to an improvement in the identification of the symptoms, the characteristics and the treatment of the disorder.
  
  
  OBJECTIVE
  The objective of this study was to analyse the correlation between latency and amplitude of the P300 component and an ecological measure of working memory in a sample of adolescents.
  
  
  METHODS
  The sample consisted of 24 boys and 7 girls aged between 12 and 18 years. P300 cognitive evoked potentials in auditory mode at Cz were registered and analysed. Furthermore, the parents filled in an executive behaviour home rating scale (BRIEF), which the working memory index was extracted from.
  
  
  RESULTS
  Significant correlations were found between the P300 amplitude and the working memory index of the BRIEF-P.
  
  
  CONCLUSIONS
  Results underline the usefulness of the P300 component for the study of its executive correlates, as well as the need to conduct further studies involving larger samples and greater complexity.
authors.affiliation: Instituto Valenciano de Neurologia Pediatrica (INVANEP), 46010 Valencia, Espana.
authors.forename: Patricia
authors.initials: P
authors.lastname: Roca
authors.forename: M Jesús
authors.initials: MJ
authors.lastname: Presentación-Herrero
authors.forename: Ana
authors.initials: A
authors.lastname: Miranda-Casas
authors.forename: Fernando
authors.initials: F
authors.lastname: Mulas
authors.forename: Pedro
authors.initials: P
authors.lastname: Ortiz-Sánchez
mesh_terms: D000161:Acoustic Stimulation; D000293:Adolescent; D001289:Attention Deficit Disorder with Hyperactivity / Q000503:physiopathology* / Q000523:psychology; D002648:Child; D018913:Event-Related Potentials, P300 / Q000502:physiology*; D056344:Executive Function / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000209:etiology / Q000503:physiopathology*; D008570:Memory, Short-Term / Q000502:physiology*; D011930:Reaction Time; D012720:Severity of Illness Index