title: A rapid and sensitive detection of HBV DNA using a nanopore sensor.
abstract: Nanopore analysis has emerged as the simplest single-molecule technique. We combined DNA probes with a nanopore electrochemical sensor for the rapid and sensitive detection of pathogenic DNA. The novel nanopore biosensor allows the single-base discrimination and detection of picomolar DNA in serum samples.
authors.affiliation: Key Laboratory of Synthetic and Natural Functional Molecule Chemistry, College of Chemistry & Materials Science, Northwest University, Xi'an 710069, P. R. China. kangxf@nwu.edu.cn.
authors.forename: Fujun
authors.initials: F
authors.lastname: Yao
authors.forename: Yani
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yongfeng
authors.initials: Y
authors.lastname: Wei
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Kang
mesh_terms: D001427:Bacterial Toxins / Q000737:chemistry; D015374:Biosensing Techniques; D004279:DNA, Viral / Q000097:blood*; D006460:Hemolysin Proteins / Q000737:chemistry; D006515:Hepatitis B virus / Q000235:genetics*; D006801:Humans; D058608:Nanopores
chemical_list: D001427:Bacterial Toxins; D004279:DNA, Viral; D006460:Hemolysin Proteins; C021091:staphylococcal alpha-toxin