title: Role of microRNAs in arbovirus/vector interactions.
abstract: The role of microRNAs (miRNAs) as small non-coding RNAs in regulation of gene expression has been recognized. They appear to be involved in regulation of a wide range of cellular pathways that affect several biological processes such as development, the immune system, survival, metabolism and host-pathogen interactions. Arthropod-borne viruses impose great economic and health risks around the world. Recent advances in miRNA biology have shed some light on the role of these small RNAs in vector-virus interactions. In this review, I will reflect on our current knowledge on the role of miRNAs in arbovirus-vector interactions and the potential avenues for their utilization in limiting virus replication and/or transmission.
authors.affiliation: Australian Infectious Disease Research Centre, School of Biological Sciences, The University of Queensland, Brisbane, QLD 4072, Australia. s.asgari@uq.edu.au.
authors.forename: Sassan
authors.initials: S
authors.lastname: Asgari
mesh_terms: D000818:Animals; D001103:Arboviruses / Q000502:physiology*; D009033:Culicidae / Q000502:physiology / Q000821:virology; D004199:Disease Vectors; D054884:Host-Pathogen Interactions; D006801:Humans; D035683:MicroRNAs / Q000235:genetics* / Q000378:metabolism; D034622:RNA Interference; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D012367:RNA, Viral / Q000235:genetics / Q000378:metabolism; D014779:Virus Replication
chemical_list: D035683:MicroRNAs; D012333:RNA, Messenger; D012367:RNA, Viral