title: [Important role of single nucleotide polymorphisms in the study of complex diseases].
abstract: Single nucleotide polymorphisms (SNPs) have been very widely used in the study of diseases and characters since the completion of the Human Genome Project. SNPs are mostly used as mere genetic markers in studying complex disease. Geneticists began to focus on the direct relationship between SNPs and complex diseases after the "Encyclopedia Of DNA Elements Project". SNPs can pay a regulative role alone, while the collected SNPs in genome can significantly affect the biological characters and disease development.
authors.affiliation: State Key Laboratory of Medical Genetics, Central South University, Changsha 410078, China.
authors.forename: Zuobin
authors.initials: Z
authors.lastname: Zhu
authors.forename: Shi
authors.initials: S
authors.lastname: Huang
mesh_terms: D004247:DNA; D004194:Disease / Q000235:genetics*; D006801:Humans; D020641:Polymorphism, Single Nucleotide
chemical_list: D004247:DNA