title: Dengue fever in patients admitted in tertiary care hospitals in Pakistan.
abstract: OBJECTIVE
  To assess the gaps in the diagnosis and management of dengue fever cases.
  
  
  METHODS
  The retrospective descriptive analytical study was done with a case record analysis of patients with dengue fever admitted from January to December 2010 at five tertiary care hospitals in different Pakistani cities. Using a questionnaire, information was gathered on demography, haematological profile, management, use of blood and platelet transfusions and the outcome. For comparison, data of serologically-confirmed dengue patients from a private laboratory in Islamabad was collected to see the age, gender and month-wise distribution of cases tested over the same period. SPSS 16 was used for statistical analysis.
  
  
  RESULTS
  Out of the 841 confirmed dengue cases, 514 (79%) were males and 139 (21%) females. The overall mean age was 31.3 +/- 14.0 years. Dengue fever was seen in 653 (78%) and dengue haemorrhagic fever (DHF) in 188 (22%) patients. Most cases were between 20 and 49 years of age. A gradual increase in dengue fever and dengue haemorrhagic fever was seen from August, with a peak in October/November. Tourniquet test was done only in 20 (2.3%) cases, out of which 11 (55%) were positive and 9 (45%) were negative. Serial haematocrit was not done in any case. Total deaths were 5 (0.6%).
  
  
  CONCLUSIONS
  Most cases were seen in October/November with the majority being in the 20-39 age group. Tourniquet test and serial haematocrit were infrequently used. No standard national guidelines were employed.
authors.forename: Muhammad Arif
authors.initials: MA
authors.lastname: Munir
authors.forename: Syed Ejaz
authors.initials: SE
authors.lastname: Alam
authors.forename: Zareef Uddin
authors.initials: ZU
authors.lastname: Khan
authors.forename: Quaid
authors.initials: Q
authors.lastname: Saeed
authors.forename: Ambreen
authors.initials: A
authors.lastname: Arif
authors.forename: Rizwan
authors.initials: R
authors.lastname: Iqbal
authors.forename: Muhammad Arif Nadeem
authors.initials: MA
authors.lastname: Saqib
authors.forename: Huma
authors.initials: H
authors.lastname: Qureshi
mesh_terms: D000328:Adult; D003715:Dengue / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D005260:Female; D006400:Hematocrit; D006801:Humans; D008297:Male; D008875:Middle Aged; D010154:Pakistan / Q000453:epidemiology; D012189:Retrospective Studies; D012621:Seasons; D062606:Tertiary Care Centers / Q000706:statistics & numerical data; D055815:Young Adult