title: Sensitivity and specificity of memory and naming tests for identifying left temporal-lobe epilepsy.
abstract: The sensitivity and specificity of the Selective Reminding Test (SRT) Delayed Recall, Wechsler Memory Scale (WMS) Logical Memory, the Boston Naming Test (BNT), and two nonverbal memory measures for detecting lateralized dysfunction in association with side of seizure focus was examined in a sample of 143 patients with left or right temporal-lobe epilepsy (TLE). Scores on the SRT and BNT were statistically significantly lower in the left TLE group compared with the right TLE group, whereas no group differences emerged on the Logical Memory subtest. No significant group differences were found with nonverbal memory measures. When the SRT and BNT were both entered as predictors in a logistic regression, the BNT, although significant, added minimal value to the model beyond the variance accounted for by the SRT Delayed Recall. Both variables emerged as significant predictors of side of seizure focus when entered into separate regressions. Sensitivity and specificity of the SRT and BNT ranged from 56% to 65%. The WMS Logical Memory and nonverbal memory measures were not significant predictors of the side of seizure focus.
authors.affiliation: a Department of Neurology , Medical College of Wisconsin , Milwaukee , Wisconsin.
authors.forename: Laura Glass
authors.initials: LG
authors.lastname: Umfleet
authors.forename: Julie K
authors.initials: JK
authors.lastname: Janecek
authors.forename: Erin
authors.initials: E
authors.lastname: Quasney
authors.forename: David S
authors.initials: DS
authors.lastname: Sabsevitz
authors.forename: Joseph J
authors.initials: JJ
authors.lastname: Ryan
authors.forename: Jeffrey R
authors.initials: JR
authors.lastname: Binder
authors.forename: Sara J
authors.initials: SJ
authors.lastname: Swanson
mesh_terms: D000328:Adult; D004833:Epilepsy, Temporal Lobe / Q000150:complications* / Q000175:diagnosis*; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000209:etiology*; D008875:Middle Aged; D009275:Names; D009483:Neuropsychological Tests; D012044:Regression Analysis; D012680:Sensitivity and Specificity; D014706:Verbal Learning; D014888:Wechsler Scales
keywords: Boston Naming Test; Selective Reminding Test; Wechsler Memory Scale; logical memory; seizure; specificity