title: Pathophysiology of Ichthyophthirius multifiliis infection in rainbow trout (oncorhynchus mykiss) and chub (Leuciscus cephalus).
abstract: The present study investigated the effect of experimental infection with Ichthyophthirius multifiliis on physiological, immunological and metabolic parameters in rainbow trout (Oncorhynchus mykiss) and chub (Leuciscus cephalus). Both species developed an immune response against I. multifiliis that was detected in the peripheral blood (i.e. increase in immunoglobulin concentrations in rainbow trout, increase in lymphocyte and thrombocyte concentrations in chub), but not in the skin mucus. Anaemia was observed in both species of fish. In rainbow trout there was also depletion of liver glycogen, disturbance in osmoregulation (decrease in serum osmolality and Na(+) and Cl(-) concentrations) and possibly also impaired wound healing capacity (i.e. decrease in skin mucus alkaline phosphatase and β-glucuronidase activity). Therefore, rainbow trout develop more severe changes following this infection compared with chub.
authors.affiliation: Animal Health Institute, Dokki, Giza, Egypt; Department of Organismic Biology, University of Salzburg, Austria.
authors.forename: G
authors.initials: G
authors.lastname: Abdel-Hafez
authors.affiliation: Department of Organismic Biology, University of Salzburg, Austria; Federal Agency for Water Management, Institute for Water Ecology, Fisheries and Lake Research, Mondsee, Austria. Electronic address: Franz.Lahnsteiner@baw.at.
authors.forename: F
authors.initials: F
authors.lastname: Lahnsteiner
authors.affiliation: Department of Theriogenology, Faculty of Veterinary Medicine, Kafrelsheikh University, Egypt.
authors.forename: N
authors.initials: N
authors.lastname: Mansour
authors.affiliation: University of Veterinary Medicine, Vienna, Austria.
authors.forename: E
authors.initials: E
authors.lastname: Licek
mesh_terms: D000818:Animals; D016770:Ciliophora Infections / Q000276:immunology / Q000503:physiopathology / Q000662:veterinary*; D003530:Cyprinidae / Q000469:parasitology*; D004797:Enzyme-Linked Immunosorbent Assay; D005393:Fish Diseases / Q000276:immunology / Q000503:physiopathology*; D016803:Hymenostomatida; D017686:Oncorhynchus mykiss / Q000469:parasitology*
keywords: Ichthyophthirius multifiliis; Leuciscus cephalus; Oncorhynchus mykiss; experimental infection