title: Effect of different surgical options on curative effect, nutrition, and health status of patients with slow transit constipation.
abstract: OBJECTIVE
  This study aims to investigate the influence of total colectomy with ileorectal anastomosis (IRA) and subtotal colectomy with cecorectal anastomosis (CRA) on curative effects, nutritional status, and health of patients with slow transit constipation (STC).
  
  
  METHODS
  The purpose of the present study is to compare the hemoglobin, the total protein level, the albumin, and the percentage of lymphocytes before and after operations. The 36-item short-form health survey questionnaire (SF-36), the mininutritional assessment (MNA), the postoperative general condition questionnaire, and the social activities questionnaire were used. The questionnaires were modified. The patients with higher scores were shown to recover better postoperatively.
  
  
  RESULTS
  More than 87.5 % of patients in both groups were satisfied with the surgery. Increased stool frequency was improved 6 months after surgery. Antidiarrheal agent use, abdominal pain, and distention in the IRA group were more frequent than in the CRA group (p < 0.05). Postoperative levels of hemoglobin, total protein level, albumin, and percentage of lymphocytes in the IRA group were higher than in the CRA group (p < 0.05). There was no difference in MNA for both groups (p > 0.05). There was no difference in the postoperative general condition questionnaire for both groups (p > 0.05). But the scores for health condition, emotion, and feeling for life were low, only 68.8 to 82.4 % at their highest.
  
  
  CONCLUSIONS
  Symptoms can be relieved by IRA and CRA surgeries. The postoperative nutritional conditions are fine. Health conditions and social life are affected. Both IRA and CRA surgeries are compliant for the treatment of STC.
authors.affiliation: Department of General Surgery, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, 400042, China.
authors.forename: Fan
authors.initials: F
authors.lastname: Li
authors.forename: Tao
authors.initials: T
authors.lastname: Fu
authors.forename: Weidong
authors.initials: W
authors.lastname: Tong
authors.forename: Anping
authors.initials: A
authors.lastname: Zhang
authors.forename: Chunxue
authors.initials: C
authors.lastname: Li
authors.forename: Yu
authors.initials: Y
authors.lastname: Gao
authors.forename: Jin Song
authors.initials: JS
authors.lastname: Wu
authors.forename: Baohua
authors.initials: B
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000714:Anastomosis, Surgical; D001798:Blood Proteins / Q000378:metabolism; D002432:Cecum / Q000601:surgery; D003082:Colectomy / Q000009:adverse effects / Q000379:methods*; D003248:Constipation / Q000601:surgery*; D005772:Gastrointestinal Transit; D006304:Health Status; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007082:Ileum / Q000601:surgery; D018655:Lymphocyte Count; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D011788:Quality of Life; D012007:Rectum / Q000601:surgery; D012709:Serum Albumin / Q000378:metabolism; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D001798:Blood Proteins; D006454:Hemoglobins; D012709:Serum Albumin