title: Colloidal micelles of block copolymers as nanoreactors, templates for gold nanoparticles, and vehicles for biomedical applications.
abstract: Target drug delivery methodology is becoming increasingly important to overcome the shortcomings of conventional drug delivery absorption method. It improves the action time with uniform distribution and poses minimum side effects, but is usually difficult to design to achieve the desire results. Economically favorable, environment friendly, multifunctional, and easy to design, hybrid nanomaterials have demonstrated their enormous potential as target drug delivery vehicles. A combination of both micelles and nanoparticles makes them fine target delivery vehicles in a variety of biological applications where precision is primarily required to achieve the desired results as in the case of cytotoxicity of cancer cells, chemotherapy, and computed tomography guided radiation therapy.
authors.affiliation: Department of Chemistry, Wilfrid Laurier University, Science Building, 75 University Ave. W., Waterloo, ON N2L 3C5, Canada. Electronic address: ms_bakshi@yahoo.com.
authors.forename: Mandeep Singh
authors.initials: MS
authors.lastname: Bakshi
mesh_terms: D003102:Colloids; D004146:Dioxanes / Q000737:chemistry*; D004337:Drug Carriers / Q000737:chemistry*; D004339:Drug Compounding; D005029:Ethylenediamines / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D006801:Humans; D007773:Lactates / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D008823:Micelles; D046529:Microscopy, Electron, Transmission; D010316:Particle Size; D020442:Poloxamer / Q000737:chemistry; D011092:Polyethylene Glycols / Q000737:chemistry*; D061089:Radiotherapy, Image-Guided / Q000379:methods
chemical_list: D003102:Colloids; D004146:Dioxanes; D004337:Drug Carriers; D005029:Ethylenediamines; D007773:Lactates; D008823:Micelles; C525597:Tetronic 904; C542362:poly(ethylene oxide)-b-poly(D,L-lactide); C088513:poly(lactic acid-ethylene glycol); D020442:Poloxamer; D011092:Polyethylene Glycols; D006046:Gold
keywords: Biomedical applications; Block copolymer micelles; Gold nanoparticles; Nanoreactors