title: Stabilization of radicals by imides. A modular stereoselective approach to protected functional 1,2-diamines.
abstract: Radical addition of various xanthates to N,N'-diacylimidazol-2-one occurs readily to give protected 1,2-diamines. The imide group stabilizes the adduct radical sufficiently to enable a second addition to unactivated alkenes. In some cases, the addition product could be converted into an indoline, a tetralone, or further added to an indole. Regioselective removal of one acyl group could also be accomplished.
authors.affiliation: Laboratoire de Synthèse Organique, UMR 7652 CNRS/Ecole Polytechnique , 91128 Palaiseau Cedex, France.
authors.forename: Songzhe
authors.initials: S
authors.lastname: Han
authors.forename: Samir Z
authors.initials: SZ
authors.lastname: Zard