title: A low cost synthesis method for functionalised iron oxide nanoparticles for magnetic hyperthermia from readily available materials.
abstract: The synthesis of iron oxide nanocrystals from reagents taken from high street sources using thermal decomposition of an iron-fatty acid precursor in a high boiling point solvent in the presence of surfactants is presented. The nanocrystals were characterised using a variety of techniques including: electron microscopy, X-ray dispersive spectroscopy, infrared spectroscopy, X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) and magnetometry. Thermogravimetric analysis (TGA) is also used to compare the decomposition behaviour of iron oleate and iron palmitate, our nanoparticle precursors. The nanoparticles also exhibit shape anisotropy when prepared under optimum conditions. We show that these nanoparticles have potential in magnetic hyperthermia after transfer to aqueous media via an amphiphilic polymer.
authors.affiliation: Materials Chemistry Research Centre, Department of Chemistry, University College London, 20 Gordon Street, London, WC1H 0AJ, UK. i.p.parkin@ucl.ac.uk.
authors.forename: Joseph C
authors.initials: JC
authors.lastname: Bear
authors.forename: Bin
authors.initials: B
authors.lastname: Yu
authors.forename: Cristina
authors.initials: C
authors.lastname: Blanco-Andujar
authors.forename: Paul D
authors.initials: PD
authors.lastname: McNaughter
authors.forename: Paul
authors.initials: P
authors.lastname: Southern
authors.forename: Marc-Krystelle
authors.initials: MK
authors.lastname: Mafina
authors.forename: Quentin A
authors.initials: QA
authors.lastname: Pankhurst
authors.forename: Ivan P
authors.initials: IP
authors.lastname: Parkin
mesh_terms: D000818:Animals; D016880:Anisotropy; D005290:Ferric Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D005395:Fish Oils / Q000737:chemistry*; D006358:Hot Temperature; D060328:Magnetic Phenomena; D053758:Nanoparticles / Q000032:analysis / Q000737:chemistry*; D010316:Particle Size; D012754:Sharks; D013499:Surface Properties; D013696:Temperature
chemical_list: D005290:Ferric Compounds; D005395:Fish Oils; C000499:ferric oxide