title: From organic pollutants to bioplastics: insights into the bioremediation of aromatic compounds by Cupriavidus necator.
abstract: Organic pollution by aromatic compounds is of increasing concern to our environment. Therefore, the transformation of aromatic pollutants into valuable aliphatic and biodegradable bioplastics was studied. Since benzoic acid was found to be the key compound for such bioremediation processes, its transformation, and metabolic pathways of digestion, by Cupriavidus necator were specifically analysed. It was found that the degradation of aromatic compounds follows the 2,3-dioxygenase pathway in this strain and that the batch transformations of benzoic acid with either fresh or adapted cells were limited to an initial concentration of 2.5 g/L of pollutant. The repeated fed-batch with partial withdrawal process, however, showed a 17.5-fold improvement, thus allowing the transformation of a total of 43.7 g/L in 12 weeks.
authors.affiliation: Materia Nova R&D Centre, Rue des Foudriers, 1, 7822 Ghislenghien, Belgium. Electronic address: nathalie.berezina@materianova.be.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Berezina
authors.affiliation: Materia Nova R&D Centre, Rue des Foudriers, 1, 7822 Ghislenghien, Belgium.
authors.forename: Bopha
authors.initials: B
authors.lastname: Yada
authors.affiliation: Materia Nova R&D Centre, Rue des Foudriers, 1, 7822 Ghislenghien, Belgium.
authors.forename: Rodrigue
authors.initials: R
authors.lastname: Lefebvre
mesh_terms: D061249:Batch Cell Culture Techniques; D001673:Biodegradation, Environmental; D018533:Biomass; D001711:Biotransformation; D020118:Cupriavidus necator / Q000378:metabolism*; D004785:Environmental Pollutants / Q000737:chemistry / Q000378:metabolism*; D005285:Fermentation; D006841:Hydrocarbons, Aromatic / Q000737:chemistry / Q000378:metabolism*; D053858:Metabolic Networks and Pathways; D010969:Plastics / Q000378:metabolism*; D013997:Time Factors
chemical_list: D004785:Environmental Pollutants; D006841:Hydrocarbons, Aromatic; D010969:Plastics