title: Neonatal survival in the Republic of Moldova--cost-effective evidence-based interventions.
abstract: OBJECTIVE
  To estimate the number of preventable neonatal deaths based on national data.
  
  
  METHODS
  To estimate the number and proportions of avoidable neonatal deaths, we have used the same approach described by Gary L. Darmstadt, using both the official statistical data and data of some assessment studies carried out in the country.
  
  
  RESULTS
  According to the calculations, the highest number of neonatal deaths we are able to prevent can be obtained from the implementation of evidence-based interventions in the frame of facility-based immediate neonatal and skilled maternal care (14 death prevented at 90% of intervention coverage and 46 deaths at 99% of intervention coverage), the early neonatal mortality rate can be reduced by 7.3% and by 24%, respectively. The second place belongs to facility-based emergency obstetric and antenatal care with an equal number of deaths that could be prevented (14 cases at 90% of intervention coverage and 35 cases at 99% of coverage).
  
  
  CONCLUSIONS
  We can conclude that due to common efforts of primary, facility-based care and public health sectors, 90% of coverage of perinatal cost-effective qualitatively implemented interventions could prevent 83 neonatal deaths (43%), while 99% of coverage could prevent 142 deaths (74%).
authors.affiliation: a Mother & Child Institute , Chisinau , Republic of Moldova.
authors.forename: Petru
authors.initials: P
authors.lastname: Stratulat
authors.forename: Ala
authors.initials: A
authors.lastname: Curteanu
authors.forename: Tatiana
authors.initials: T
authors.lastname: Caraus
mesh_terms: D003362:Cost-Benefit Analysis; D005260:Female; D006801:Humans; D007223:Infant; D007226:Infant Mortality; D007231:Infant, Newborn; D008427:Maternal Health Services / Q000191:economics / Q000592:standards / Q000706:statistics & numerical data; D008428:Maternal Mortality; D008966:Moldova / Q000453:epidemiology; D018743:Perinatal Care / Q000191:economics / Q000592:standards / Q000706:statistics & numerical data; D011247:Pregnancy; D011295:Prenatal Care / Q000191:economics / Q000592:standards / Q000706:statistics & numerical data
keywords: Maternal and newborn health; neonatal mortality; package of interventions; perinatal health reform