title: How Kinetochores CCAN resist force.
abstract: Kinetochores orchestrate chromosome segregation during mitosis and must cope with dynamic forces generated by attached microtubules. In this issue of Developmental Cell, Suzuki et al. (2014) demonstrate that the constitutive centromere-associated network (CCAN) displays a complex architecture that plays a crucial role in resisting these forces.
authors.affiliation: Mechanochemical Cell Biology Building, Division of Biomedical Cell Biology, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK. Electronic address: a.d.mcainsh@warwick.ac.uk.
authors.forename: Andrew D
authors.initials: AD
authors.lastname: McAinsh
mesh_terms: D000818:Animals; D018386:Kinetochores / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism*; D008941:Spindle Apparatus / Q000378:metabolism*