title: [Determination of the pancreatic inflammatory process activity in chronic pancreatitis].
abstract: There were 21 patients examined, who suffered chronic pancreatitis (CHP) in different activity of pancreatic inflammatory process. In the blood serum the contents of the inflammation markers was determined: tumor necrosis factor-alpha (TNF-alpha) and interleukin-10 (IL-10), ratio TNF-alpha/IL-10 was calculated, as well as activity of elastase in feces. Analysis of these indices permits to estimate the activity of pancreatic inflammatory process in patients, suffering CHP, what secures rising of the preoperative diagnosis and treatment efficacy, as well as reduction of intra- and postoperative complications rate.
authors.forename: B F
authors.initials: BF
authors.lastname: Shevchenko
authors.forename: O M
authors.initials: OM
authors.lastname: Babiĭ
authors.forename: O M
authors.initials: OM
authors.lastname: Tatarchuk
authors.forename: V Ie
authors.initials: VIe
authors.lastname: Kudriavtseva
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005243:Feces / Q000201:enzymology; D006801:Humans; D016753:Interleukin-10 / Q000097:blood*; D008875:Middle Aged; D010196:Pancreatic Elastase / Q000032:analysis*; D050500:Pancreatitis, Chronic / Q000097:blood / Q000276:immunology*; D012720:Severity of Illness Index; D014409:Tumor Necrosis Factor-alpha / Q000097:blood*
chemical_list: C508609:IL10 protein, human; D014409:Tumor Necrosis Factor-alpha; D016753:Interleukin-10; D010196:Pancreatic Elastase