title: Synthesis of dihydrobenzoheterocycles through Al(OTf)3-mediated cascade cyclization and ionic hydrogenation.
abstract: A facile and versatile synthesis of dihydrobenzoheterocycles via Al(OTf)3-mediated cascade cyclization and ionic hydrogenation has been developed. The reaction is applicable to a wide range of substrates with various functional groups to afford the corresponding products in good yields.
authors.affiliation: State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, and ‡Beijing Key Laboratory of Active Substances Discovery and Drugability Evaluation, Department of Medicinal Chemistry, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing 100050, P. R. China.
authors.forename: Yulin
authors.initials: Y
authors.lastname: Tian
authors.forename: Xiaojian
authors.initials: X
authors.lastname: Wang
authors.forename: Qiong
authors.initials: Q
authors.lastname: Xiao
authors.forename: Chenbin
authors.initials: C
authors.lastname: Sun
authors.forename: Dali
authors.initials: D
authors.lastname: Yin
mesh_terms: D002384:Catalysis; D003500:Cyclization; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D006865:Hydrogenation; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D006571:Heterocyclic Compounds; D008698:Mesylates; C012077:trifluoromethanesulfonic acid