title: A new natural nucleotide and other antibacterial metabolites from an endophytic Nocardia sp.
abstract: Nine compounds were isolated from Nocardia sp. YIM 64630, and their structures were elucidated as 5'-O-acetyl-2'-deoxyuridine (1), 22E,24R-5α,6α-epoxyergosta-8(14),22-diene-3β,7α-diol (2), 22E,24R-5α,6α-epoxyergosta-8,22-diene-3β,7α-diol (3), 22E,24R-ergosta-7,22-diene-3β,5α,6β-triol (4), 5α,8α-epidioxyergosta-6,22-dien-3β-ol (5), 4',5,6-trihydroxy-7-methoxyisoflavone (6), 2,4,4'-trihydroxy-deoxybenzoin (7), methyl [4-hydroxyphenyl]acetate (8) and daidzein by extensive spectroscopic analyses. Compound 1 was isolated from natural resources for the first time. The antimicrobial and antioxidant activities of compounds 1-8 were investigated.
authors.affiliation: a School of Chemical Science and Technology, Yunnan University , Kunming 650091 , P.R. China.
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Xueqiong
authors.initials: X
authors.lastname: Yang
authors.forename: Yabin
authors.initials: Y
authors.lastname: Yang
authors.forename: Shaohuan
authors.initials: S
authors.lastname: Qin
authors.forename: Qiling
authors.initials: Q
authors.lastname: Li
authors.forename: Lixing
authors.initials: L
authors.lastname: Zhao
authors.forename: Zhongtao
authors.initials: Z
authors.lastname: Ding
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D009615:Nocardia / Q000737:chemistry*; D009711:Nucleotides / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D009711:Nucleotides
keywords: Nocardia sp; antibacterial metabolites; endophyte