title: Acquired progressive lymphangioma of the nipple.
abstract: A 47-year-old woman presented with left nipple itch and discomfort. On physical examination she was found to have a 7 mm lesion. She underwent bilateral mammography and bilateral breast ultrasound which were normal. A punch biopsy of the lesion was performed in the office and the specimen submitted to pathology. Histopathological examination showed ectatic vascular spaces lined by flattened, cytologically bland endothelial cells dissecting the dermal collagen. Evident lymphatic valves were present within the vascular spaces confirming that the vessels were lymphatic in nature. The diagnosis of acquired progressive lymphangioma (benign lymphangioendothelioma) was rendered.
authors.affiliation: Department of Surgery, Cleveland Clinic, Cleveland, Ohio, USA.
authors.forename: Eyas
authors.initials: E
authors.lastname: Alkhalili
authors.affiliation: Department of Internal Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
authors.forename: Houriya
authors.initials: H
authors.lastname: Ayoubieh
authors.affiliation: Department of Surgery, Cleveland clinic, Twinsburg, Ohio, USA.
authors.forename: William
authors.initials: W
authors.lastname: O'Brien
authors.affiliation: Department of Pathology, Cleveland Clinic, Cleveland, Ohio, USA.
authors.forename: Steven D
authors.initials: SD
authors.lastname: Billings
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008202:Lymphangioma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D009558:Nipples / Q000473:pathology / Q000601:surgery