title: Biomechanical comparison of mono-segment transpedicular fixation with short-segment fixation for treatment of thoracolumbar fractures: a finite element analysis.
abstract: Mono-segment transpedicular fixation is a method for the treatment of certain types of thoracolumbar spinal fracture. Finite element models were constructed to evaluate the biomechanics of mono-segment transpedicular fixation of thoracolumbar fracture. Spinal motion (T10-L2) was scanned and used to establish the models. The superior half of the cortical bone of T12 was removed and the superior half of the cancellous bone of the T12 body was assigned the material properties of injured bone to mimic vertebral fracture. Transpedicular fixation of T11 and T12 was performed to produce a mono-segment fixation model; T11 and L1 were fixed to produce a short-segment fixation model. Motion differences between functional units and von Mises stress on the spine and implants were measured under axial compression, anterior bending, extensional bending, lateral bending and axial rotation. We found no significant difference between mono- and short-segment fixations in the motion of any functional unit. Stress on the T10/T11 nucleus pulposus and T10/T11 and L1/L2 annulus fibrosus increased significantly by about 75% on anterior bending, extensional bending and lateral bending. In the fracture model, stress was increased by 24% at the inferior endplate of T10 and by 43% at the superior endplate of L2. All increased stresses were reduced after fixation and lower stress was observed with mono-segment fixation. In summary, the biomechanics of mono-segment pedicle screw instrumentation was similar to that of conventional short-segment fixation. As a minimally invasive treatment, mono-segment fixation would be appropriate for the treatment of selected thoracolumbar spinal fractures.
authors.affiliation: Department of Orthopaedics, Tianjin Hospital, Tianjin, People's Republic of China.
authors.forename: Guijun
authors.initials: G
authors.lastname: Xu
authors.affiliation: Department of Orthopaedics, Tianjin Hospital, Tianjin, People's Republic of China.
authors.forename: Xin
authors.initials: X
authors.lastname: Fu
authors.affiliation: Department of Orthopedics, Binzhou Medical University Hospital, Shandong, People's Republic of China.
authors.forename: Changling
authors.initials: C
authors.lastname: Du
authors.affiliation: Biomechanics Labs of Orthopaedic Institute, Tianjin Hospital, Tianjin, People's Republic of China.
authors.forename: Jianxiong
authors.initials: J
authors.lastname: Ma
authors.affiliation: Department of Orthopaedics, Tianjin Medical University General Hospital, Tianjin, People's Republic of China Department of Immunology, Tianjin Medical University, Tianjin, People's Republic of China.
authors.forename: Zhijun
authors.initials: Z
authors.lastname: Li
authors.affiliation: Department of Orthopaedics, Tianjin Hospital, Tianjin, People's Republic of China.
authors.forename: Peng
authors.initials: P
authors.lastname: Tian
authors.affiliation: Department of Orthopaedics, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.
authors.forename: Tao
authors.initials: T
authors.lastname: Zhang
authors.affiliation: Biomechanics Labs of Orthopaedic Institute, Tianjin Hospital, Tianjin, People's Republic of China spiritseeker2008@gmail.com hansontijmu@gmail.com.
authors.forename: Xinlong
authors.initials: X
authors.lastname: Ma
mesh_terms: D001863:Bone Screws; D019245:Compressive Strength; D003198:Computer Simulation; D055119:Elastic Modulus; D020342:Finite Element Analysis; D005593:Fracture Fixation, Internal / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D008954:Models, Biological; D009068:Movement; D016103:Spinal Fractures / Q000503:physiopathology* / Q000601:surgery*; D013718:Tensile Strength; D013904:Thoracic Vertebrae / Q000293:injuries* / Q000503:physiopathology* / Q000601:surgery; D016896:Treatment Outcome; D016474:Weight-Bearing
keywords: Thoracolumbar fracture; biomechanics; finite element analysis; mono-segment fixation; short-segment fixation