title: Intracranial hypertension due to levothyroxine use.
abstract: We report a case of intracranial hypertension in a 13-year-old boy on levothyroxine therapy for hypothyroidism and review the literature describing this rare association. He presented with severe headaches and was found to have bilateral optic disk edema and elevated intracranial pressure shortly after an increase in his dosage of levothyroxine. The optic disk edema and headaches resolved with decreasing the levothyroxine and initiating acetazolamide.
authors.affiliation: Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas.
authors.forename: Casey J
authors.initials: CJ
authors.lastname: Beal
authors.affiliation: Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas.
authors.forename: Kristina Y
authors.initials: KY
authors.lastname: Pao
authors.affiliation: Department of Neuro-ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas; Department of Ocular Pathology, University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address: Nick.Hogan@utsouthwestern.edu.
authors.forename: R Nick
authors.initials: RN
authors.lastname: Hogan
mesh_terms: D000293:Adolescent; D006261:Headache / Q000139:chemically induced / Q000503:physiopathology; D006801:Humans; D007037:Hypothyroidism / Q000188:drug therapy; D019586:Intracranial Hypertension / Q000139:chemically induced* / Q000503:physiopathology; D007427:Intracranial Pressure / Q000187:drug effects* / Q000502:physiology; D008297:Male; D010211:Papilledema / Q000139:chemically induced / Q000503:physiopathology; D013974:Thyroxine / Q000009:adverse effects*
chemical_list: D013974:Thyroxine