title: Stenotrophomonas maltophilia: rare cause of meningitis.
abstract: Stenotrophomonas maltophilia is a Gram-negative bacillus, which is an extremely rare cause of meningitis. To our knowledge, there are only five previous pediatrics cases. Here, we describe the case of a 4-year-old boy who developed meningitis associated with this organism, after several neurosurgical procedures and previous treatment with a broad-spectrum antibiotic. He was treated successfully with a combination of trimethoprim-sulfamethoxazole, ceftazidime and levofloxacin. Stenotrophomonas maltophilia should be considered as a potential cause of meningitis, especially among severely debilitated or immunosuppressed patients. Antimicrobial therapy is complicated by the high resistance of the organism to multiple antibiotics.
authors.affiliation: Department of Pediatrics, São Francisco Xavier Hospital, Lisbon, Portugal.
authors.forename: Cátia Rodrigues
authors.initials: CR
authors.lastname: Correia
authors.forename: Sara Tavares
authors.initials: ST
authors.lastname: Ferreira
authors.forename: Paula
authors.initials: P
authors.lastname: Nunes
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002442:Ceftazidime / Q000008:administration & dosage*; D002675:Child, Preschool; D004338:Drug Combinations; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy*; D006801:Humans; D064704:Levofloxacin / Q000008:administration & dosage*; D008297:Male; D016920:Meningitis, Bacterial / Q000188:drug therapy*; D020615:Stenotrophomonas maltophilia; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000008:administration & dosage*
chemical_list: D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D064704:Levofloxacin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D002442:Ceftazidime
keywords: Stenotrophomonas maltophilia; levofloxacin; meningitis