title: Wavefront analysis after wavefront-guided myopic LASIK using a new generation aberrometer.
abstract: OBJECTIVE
  To evaluate the short-term aberrometric outcomes of wavefront-guided LASIK for the correction of low to moderate myopia and myopic astigmatism using a new generation aberrometer (iDesign System; Abbott Medical Optics, Inc., Santa Ana, CA).
  
  
  METHODS
  Charts of 92 eyes of 46 patients successively treated by wavefront-guided LASIK for myopia and/or myopic astigmatism were retrospectively reviewed at 3 months postoperatively. Aberrometric analysis of the wavefront errors was performed for a 6-mm pupil diameter to investigate the surgical induction of the total higher-order aberrations (HOAs), spherical aberrations Z41, and coma-like aberrations Z3 . Additionally, correlations between the magnitude of aberrations induced with the level of achieved correction and the preoperative amount of aberrations were tested.
  
  
  RESULTS
  A minimal but statistically significant induction in all of the aberrations tested was observed at 3 months postoperatively (P < .01), with an increase (calculated for a 6-mm pupil) of +0.12 + 0.2, +0.06 + 0.1, and 0.05 + 0.1 pm in the root mean square (RMS) total HOA, RMS spherical aberration Z41, and RMS coma Z31, respectively. The postoperative change in aberrations was poorly correlated with both the level of achieved myopic correction for all of the aberrations tested (r < 0.3; P < .001) and the preoperative level of spherical aberrations (r = 0.3; P < .05) and coma (r = 0.46; P < .05).
  
  
  CONCLUSIONS
  Wavefront-guided LASIK using the new generation Hartmann-Shack aberrometer allows a minimal induction of HOAs regardless of the level of myopic correction achieved or the preoperative magnitude of aberrations.
authors.forename: David
authors.initials: D
authors.lastname: Smadja
authors.forename: Tania
authors.initials: T
authors.lastname: De Castro
authors.forename: Laury
authors.initials: L
authors.lastname: Tellouck
authors.forename: Joy
authors.initials: J
authors.lastname: Tellouck
authors.forename: Fanny
authors.initials: F
authors.lastname: Lecomte
authors.forename: David
authors.initials: D
authors.lastname: Touboul
authors.forename: Clement
authors.initials: C
authors.lastname: Paya
authors.forename: Marcony R
authors.initials: MR
authors.lastname: Santhiago
mesh_terms: D057128:Aberrometry / Q000295:instrumentation*; D000328:Adult; D001251:Astigmatism / Q000503:physiopathology / Q000601:surgery; D003315:Cornea / Q000503:physiopathology / Q000601:surgery; D057108:Corneal Wavefront Aberration / Q000503:physiopathology*; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult