title: The ventral route to intracranial aneurysm: from the origin towards modern transsphenoidal surgery. An historical review and current perspective.
abstract: A review of the main studies that have explored the use of the ventral pathway for treatment of intracranial aneurysms,including the recent reported extended transsphenoidal approaches.
  
  
  
  A comprehensive literature review was performed using the PubMed database. We recovered 48 cases of cerebral aneurysms, approached via the transcervical-transclival, transoral-transclival, transfacial-transclival ventral pathways and the extended transsphenoidal route. The overall rates of complications and surgical success were evaluated and compared for both traditional ventral and transsphenoidal approaches.
  
  
  
  For traditional routes, the overall complications and surgical success rates were 74% (26/35) and 87% (13115), respectively.For extended transsphenoidal approaches were 44% (4/9) and 78% (7 /9), respectively.
  
  
  
  Our paper is a reconnaissance of what has been done via "the anterior route" and a notification of the existence of this "surgical window': Present and future of cerebral aneurysm treatment is represented by the endovascular technique. A few selected cases in specialized centers, where transsphenoidal approaches with the aid of the endoscope are routinely performed,may be treated with such techniques alone or in combination with other different procedures. Further studies in large numbers of patients will be required to validate the full benefit of this approach.
authors.forename: A
authors.initials: A
authors.lastname: Di Somma
authors.forename: M
authors.initials: M
authors.lastname: de Notaris
authors.forename: J
authors.initials: J
authors.lastname: Ensenat
authors.forename: I
authors.initials: I
authors.lastname: Alobid
authors.forename: M
authors.initials: M
authors.lastname: Bernal-Sprekelsen
authors.forename: L M
authors.initials: LM
authors.lastname: Cavallo
authors.forename: A
authors.initials: A
authors.lastname: Prats-Galino
authors.forename: P
authors.initials: P
authors.lastname: Cappabianca
mesh_terms: D019723:Endoscopes; D049673:History, 20th Century; D006801:Humans; D002532:Intracranial Aneurysm / Q000266:history* / Q000601:surgery*; D019635:Neurosurgical Procedures / Q000009:adverse effects / Q000266:history* / Q000379:methods; D013100:Sphenoid Bone / Q000601:surgery