title: Rh(III)-catalyzed traceless coupling of quinoline N-oxides with internal diarylalkynes.
abstract: Quinoline N-oxides were found to undergo Cp*Rh(III)-catalyzed coupling with internal diarylalkynes to provide 8-functionalized quinolines through a cascade process that involves remote C-H bond activation, alkyne insertion, and intramolecular oxygen atom transfer. In this reaction, the N-oxide plays a dual role, acting as a traceless directing group as well as a source of oxygen atom, as confirmed by an (18)O-labeling experiment.
authors.affiliation: Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS) , Daejeon 307-701, Korea.
authors.forename: Upendra
authors.initials: U
authors.lastname: Sharma
authors.forename: Yoonsu
authors.initials: Y
authors.lastname: Park
authors.forename: Sukbok
authors.initials: S
authors.lastname: Chang
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003497:Cyclic N-Oxides / Q000737:chemistry*; D015394:Molecular Structure; D011804:Quinolines / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*
chemical_list: D000480:Alkynes; D003497:Cyclic N-Oxides; D011804:Quinolines; D012238:Rhodium