title: [Myocardial ischemia caused by overuse of headache medications].
abstract: Myocardial infarction as the most severe clinical manifestation of coronary atherosclerosis is the major cause of death in western countries. Although rupture of an atherosclerotic plaque is generally causal for this event, in recent years differential diagnoses have been discussed to further optimize diagnosis and treatment of myocardial ischemia. The "universal definition of myocardial infarction" defines five subtypes of myocardial infarction: in particular, type 2 myocardial infarction includes other diseases related to myocardial ischemia such as hyper- or hypotension, coronary artery spasms, arrhythmia, etc. Some medications for the acute therapy of migraine like triptans can lead to myocardial infarction.
authors.affiliation: Universitätsklinik und Poliklinik für Neurologie, Universitätsklinikum Halle (Saale), Ernst-Grube-Str. 40, 06120, Halle (Saale), Deutschland, torsten.kraya@medizin.uni-halle.de.
authors.forename: T
authors.initials: T
authors.lastname: Kraya
authors.forename: A
authors.initials: A
authors.lastname: Schlitt
mesh_terms: D003131:Combined Modality Therapy; D057915:Drug Substitution; D005260:Female; D006801:Humans; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy*; D009203:Myocardial Infarction / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D017202:Myocardial Ischemia / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D010880:Piperidines / Q000008:administration & dosage / Q000009:adverse effects*; D012651:Self Medication; D019966:Substance-Related Disorders / Q000150:complications*; D014363:Tryptamines / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D010880:Piperidines; D014363:Tryptamines; C106783:naratriptan