title: Diagnostic pitfalls of drug-induced immune hemolytic anemia.
abstract: Immune hemolytic anemia (IHA) is a rare complication of drug administration. However, its true incidence remains obscure, as there are a number of factors that may lead to misdiagnosis. The clinical and serologic pictures are variable, and there is a great deal of unawareness that certain drugs can cause IHA. Furthermore, serologic results can be easily misinterpreted, resulting in a wrong diagnosis.
authors.affiliation: MD, Medical Director (corresponding author).
authors.forename: Abdulgabar
authors.initials: A
authors.lastname: Salama
authors.affiliation: MD, Immunohematology Reference Laboratory, Institute of Transfusion Medicine, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
authors.forename: Beate
authors.initials: B
authors.lastname: Mayer
mesh_terms: D000368:Aged; D000744:Anemia, Hemolytic, Autoimmune / Q000139:chemically induced / Q000175:diagnosis* / Q000276:immunology; D000936:Antigen-Antibody Complex / Q000097:blood; D000959:Antihypertensive Agents / Q000009:adverse effects; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects / Q000276:immunology; D001323:Autoantibodies / Q000097:blood; D002478:Cells, Cultured; D003298:Coombs Test; D004912:Erythrocytes / Q000187:drug effects / Q000276:immunology; D005189:False Positive Reactions; D017809:Fatal Outcome; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects / Q000276:immunology; D006461:Hemolysis / Q000276:immunology; D006801:Humans; D006852:Hydrochlorothiazide / Q000009:adverse effects / Q000031:analogs & derivatives; D008875:Middle Aged; D009627:Nomifensine / Q000009:adverse effects
chemical_list: D000936:Antigen-Antibody Complex; D000959:Antihypertensive Agents; D000964:Antimetabolites, Antineoplastic; D001323:Autoantibodies; D006852:Hydrochlorothiazide; D009627:Nomifensine; D005472:Fluorouracil; C009732:buthiazide