title: Salivary gland tumors in children: a retrospective clinical review.
abstract: Seven patients with salivary gland tumors who underwent between 1972 and 2012 were retrospectively evaluated. The age of the patients ranged from 6.3 to 13 years old; five were females and two were males. Five patients had stage IVa, one patient had stage I, and one patient had stage II disease. The surgical margin was found to be positive in five cases. There were three adenoid cystic carcinoma, two adenocarcinoma, one anaplastic carcinoma, and one mucoepidermoid carcinoma. There were five parotid, one lacrimal gland, and one palatal involvement. Three patients who had low stage tumors were treated with surgery alone. Four of the cases received adjuvant radiation and chemotherapy. One patient with parotid tumor died with progressive disease. One case with lacrimal gland neoplasm was alive 48 months after discontinuation of treatment. The other palate case was lost to follow-up 1 month after the beginning of the treatment. Surgery is the primary treatment, with radiotherapy and chemotherapy used as adjuvant treatments. The treatment options need to be selected and planned for each individual patient.
authors.affiliation: Department of Pediatric Oncology, Cancer Institute, Hacettepe University , Ankara , Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Varan
authors.forename: Canan
authors.initials: C
authors.lastname: Akyüz
authors.forename: Erman
authors.initials: E
authors.lastname: Ataş
authors.forename: Taşkın
authors.initials: T
authors.lastname: Yücel
authors.forename: Burça
authors.initials: B
authors.lastname: Aydın
authors.forename: Bilgehan
authors.initials: B
authors.lastname: Yalçın
authors.forename: Tezer
authors.initials: T
authors.lastname: Kutluk
authors.forename: Münevver
authors.initials: M
authors.lastname: Büyükpamukçu
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000628:therapy; D008949:Adenoma, Pleomorphic / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D000293:Adolescent; D000970:Antineoplastic Agents / Q000627:therapeutic use; D003528:Carcinoma, Adenoid Cystic / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D018277:Carcinoma, Mucoepidermoid / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D059186:Chemoradiotherapy, Adjuvant; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D010307:Parotid Neoplasms / Q000401:mortality / Q000628:therapy; D012468:Salivary Gland Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000628:therapy*; D014421:Turkey
chemical_list: D000970:Antineoplastic Agents
keywords: children; outcome; salivary gland tumors; treatment