title: Ruthenium(II)-catalyzed direct addition of indole/pyrrole C2-H bonds to alkynes.
abstract: A ruthenium-catalyzed C2-hydroindolation of alkynes has been achieved. This protocol provides a rapid and concise access to kinds of 2-alkenyl-substituted N-(2-pyridyl)indoles in which the pyridyl moiety can be easily removed to afford free (N-H) indoles under mild conditions. Various arenes and alkynes, including electron-deficient and electron-rich internal alkynes and terminal alkynes, allow for this transformation.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510641, China.
authors.forename: Libo
authors.initials: L
authors.lastname: Liang
authors.forename: Shaomin
authors.initials: S
authors.lastname: Fu
authors.forename: Dongen
authors.initials: D
authors.lastname: Lin
authors.forename: Xiao-Qi
authors.initials: XQ
authors.lastname: Zhang
authors.forename: Yuanfu
authors.initials: Y
authors.lastname: Deng
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang
authors.forename: Wei
authors.initials: W
authors.lastname: Zeng
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D006860:Hydrogen Bonding; D007211:Indoles / Q000737:chemistry*; D015394:Molecular Structure; D011758:Pyrroles / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry
chemical_list: D000480:Alkynes; D007211:Indoles; D011758:Pyrroles; D012428:Ruthenium; C030374:indole