title: Practical preterm parenteral nutrition: systematic literature review and recommendations for practice.
abstract: Current practice in relation to the prescribing, compounding and administration of parenteral nutrition for extremely preterm infants is inconsistent and based on largely historical evidence. Increasingly there are calls for more 'aggressive' nutritional interventions to prevent 'postnatal growth failure'. However the evidence base for these recommendations is weak, and there are no long-term studies examining the impact of such practices. Here we summarise the evidence for preterm parenteral nutrition interventions. We suggest principles to guide practice based on evidence from a systematic search and review of evidence to date, and recommend actions necessary to advance the understanding of this important aspect of preterm care.
authors.affiliation: Imperial College London, UK; Chelsea Westminster Hospital NHS Foundation Trust, London, UK. Electronic address: s.uthaya@imperial.ac.uk.
authors.forename: S
authors.initials: S
authors.lastname: Uthaya
authors.affiliation: Imperial College London, UK; Chelsea Westminster Hospital NHS Foundation Trust, London, UK. Electronic address: n.modi@imperial.ac.uk.
authors.forename: N
authors.initials: N
authors.lastname: Modi
mesh_terms: D000596:Amino Acids / Q000008:administration & dosage / Q000378:metabolism; D006801:Humans; D007227:Infant Nutritional Physiological Phenomena / Q000502:physiology*; D007231:Infant, Newborn; D007234:Infant, Premature / Q000378:metabolism / Q000502:physiology*; D050356:Lipid Metabolism; D008055:Lipids / Q000008:administration & dosage; D044342:Malnutrition / Q000628:therapy; D018673:Nutrition Policy; D010288:Parenteral Nutrition / Q000379:methods*
chemical_list: D000596:Amino Acids; D008055:Lipids
keywords: Amino acids; Infant; Intravenous lipids; Newborn intensive care; Nutrition; Parenteral nutrition; Prematurity