title: Congestive Heart Failure With Apparently Preserved Left Ventricular Systolic Function: A 10-Year Observational Study.
abstract: We analyzed the clinical presentation and outcomes (from 2003 to 2013) of heart failure (HF) with apparently normal systolic function (HFPEF). Based on the echocardiographic left ventricular ejection fraction (LVEF), patients were divided into 2 groups, group 1 (<50%) and group 2 (≥50%). Of 2212 patients with HF, 20% were in group 2. Patients in group 2 were more likely to be older, females, Arabs, hypertensive, and obese (P = .001). Patients in group 1 were mostly Asians and had more troponin-T positivity (P = .001). Inhospital cardiac arrest, shock, and deaths were significantly greater in group 1. On multivariate analysis, age, ST-segment elevation myocardial infarction, lack of on-admission β-blockers, and angiotensin-converting enzyme inhibitors use were independent predictors of mortality. HFPEF is associated with less mortality compared to those who presented with reduced LVEF. On admission, use of evidence-based medications could in part predict this difference in the hospital outcome.
authors.affiliation: Department of Clinical Medicine, Weill Cornell Medical School, Doha, Qatar Clinical Research, Trauma Section, Hamad Medical Corporation (HMC), Doha, Qatar Internal Medicine, Cardiology Section, Ahmed Maher Teaching Hospital, Cairo, Egypt aymanco65@yahoo.com.
authors.forename: Ayman
authors.initials: A
authors.lastname: El-Menyar
authors.affiliation: Cardiology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
authors.forename: Adel
authors.initials: A
authors.lastname: Shabana
authors.affiliation: Department of Cardiology and Cardiovascular Surgery, Heart Hospital, HMC, Doha, Qatar.
authors.forename: Abdulrahman
authors.initials: A
authors.lastname: Arabi
authors.affiliation: Vascular Section, Hamad Medical Corporation (HMC), Doha, Qatar.
authors.forename: Hassan
authors.initials: H
authors.lastname: Al-Thani
authors.affiliation: Department of Cardiology and Cardiovascular Surgery, Heart Hospital, HMC, Doha, Qatar.
authors.forename: Nidal
authors.initials: N
authors.lastname: Asaad
authors.affiliation: Cardiology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
authors.forename: Hajar
authors.initials: H
authors.lastname: AlBinALi
authors.affiliation: Cardiovascular Research, Heart Hospital, HMC, Doha, Qatar.
authors.forename: Rajvir
authors.initials: R
authors.lastname: Singh
authors.affiliation: Department of Cardiology and Cardiovascular Surgery, Heart Hospital, HMC, Doha, Qatar.
authors.forename: Mohammed
authors.initials: M
authors.lastname: Gomaa
authors.affiliation: Department of Cardiology and Cardiovascular Surgery, Heart Hospital, HMC, Doha, Qatar.
authors.forename: A
authors.initials: A
authors.lastname: Gehani
mesh_terms: D000367:Age Factors; D000368:Aged; D015415:Biomarkers / Q000097:blood; D002317:Cardiovascular Agents / Q000627:therapeutic use; D015897:Comorbidity; D005260:Female; D006333:Heart Failure / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy / Q000208:ethnology / Q000401:mortality / Q000503:physiopathology*; D017052:Hospital Mortality; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011379:Prognosis; D011780:Qatar / Q000453:epidemiology; D044469:Racial Groups; D012189:Retrospective Studies; D012307:Risk Factors; D013318:Stroke Volume; D013599:Systole; D013997:Time Factors; D020107:Troponin T / Q000097:blood; D016277:Ventricular Function, Left
chemical_list: D015415:Biomarkers; D002317:Cardiovascular Agents; D020107:Troponin T
keywords: Qatar; congestive heart failure; diastolic function; ejection fraction; mortality; systolic function