title: Highly efficient and selective phosphorylation of amino acid derivatives and polyols catalysed by 2-aryl-4-(dimethylamino)pyridine-N-oxides--towards kinase-like reactivity.
abstract: The chemoselective phosphorylation of hydroxyl containing amino acid derivatives and polyols by phosphoryl chlorides catalyzed by 2-aryl-4-(dimethylamino)pyridine-N-oxides is described.
authors.affiliation: Department of Chemistry, South Kensington Campus, Imperial College London, SW7 2AZ, UK. a.c.spivey@imperial.ac.uk.
authors.forename: James I
authors.initials: JI
authors.lastname: Murray
authors.forename: Rudiger
authors.initials: R
authors.lastname: Woscholski
authors.forename: Alan C
authors.initials: AC
authors.lastname: Spivey
mesh_terms: D000596:Amino Acids / Q000737:chemistry / Q000378:metabolism; D002384:Catalysis; D017553:Phosphorus Compounds / Q000737:chemistry; D010766:Phosphorylation; D011108:Polymers / Q000737:chemistry*; D011505:Protein-Tyrosine Kinases / Q000737:chemistry / Q000378:metabolism; D011725:Pyridines / Q000737:chemistry*; D014443:Tyrosine / Q000737:chemistry / Q000378:metabolism
chemical_list: D000596:Amino Acids; D017553:Phosphorus Compounds; D011108:Polymers; D011725:Pyridines; C024617:polyol; D014443:Tyrosine; C013229:pyridine N-oxide; C013196:phosphoryl chloride; D011505:Protein-Tyrosine Kinases