title: Modifications of biochemical parameters related to protein metabolism and renal function in male soccer players after a match.
abstract: OBJECTIVE
  The impact of a soccer match on parameters related to protein catabolism and renal function was evaluated in male players.
  
  
  METHODS
  Blood was collected before and immediately after a 90 minutes soccer match from 19 athletes of two first division teams in Brazil. Red blood cells (RBC), hemoglobin (Hb), hematocrit (Ht), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC), ammonia, uric acid, urea and creatinine were analyzed. The modification of plasma volume was calculated, and biochemical values were corrected for this change. Urea/creatinine ratio and equations to estimate the glomerular filtration rate (eGFR) were used to assess kidney function.
  
  
  RESULTS
  Plasma volume decreased from pre- to post-match. Post-match values higher than the pre-match ones were observed for RBC, Hb and Ht, as a consequence of plasma volume decrease. An increase in ammonia and creatinine concentrations post-match in comparison with pre-match values was registered, without changes in uric acid and urea levels. A reduction in urea/creatinine ratio and in eGFR was observed post-match, suggesting a decrease of renal function.
  
  
  CONCLUSIONS
  A soccer match induced alterations in parameters linked to renal function and protein metabolism in male athletes. Particular attention should be paid in the monitoring of the ammonia concentration as an indicator of metabolic activity and energy requirement during prolonged exercise.
authors.affiliation: Laboratory of Experimental Biochemistry and Molecular Biology, I.R.C.C.S. Istituto Ortopedico Galeazzi, Milan, Italy - alessandra.colombini@grupposandonato.it.
authors.forename: A
authors.initials: A
authors.lastname: Colombini
authors.forename: M
authors.initials: M
authors.lastname: Machado
authors.forename: G
authors.initials: G
authors.lastname: Lombardi
authors.forename: P
authors.initials: P
authors.lastname: Lanteri
authors.forename: G
authors.initials: G
authors.lastname: Banfi
mesh_terms: D000328:Adult; D000641:Ammonia / Q000097:blood; D015415:Biomarkers / Q000097:blood*; D003404:Creatinine / Q000097:blood; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000502:physiology*; D008297:Male; D009124:Muscle Proteins / Q000378:metabolism*; D012916:Soccer / Q000502:physiology*; D014508:Urea / Q000097:blood; D014527:Uric Acid / Q000097:blood
chemical_list: D015415:Biomarkers; D009124:Muscle Proteins; D014527:Uric Acid; D000641:Ammonia; D014508:Urea; D003404:Creatinine