title: Molecular recognition of nucleic acids by nucleolipid/dendrimer surface complexes.
abstract: We show for the first time that 1,2-dilauroyl-sn-glycero-3-phosphatidyladenosine nucleolipid surface complexes with cationic poly(amidoamine) dendrimers can be used to selectively bind DNA including oligonucleotides. This molecular recognition has high potential for applications involving biomedical and bioanalytic devices as well as drug delivery systems based on nucleic acids.
authors.affiliation: Physical Chemistry, Department of Chemistry, Lund University, P. O. Box 124, S-221 00 Lund, Sweden. Tommy.Nylander@fkem1.lu.se.
authors.forename: Marianna Yanez
authors.initials: MY
authors.lastname: Arteta
authors.forename: Debora
authors.initials: D
authors.lastname: Berti
authors.forename: Costanza
authors.initials: C
authors.lastname: Montis
authors.forename: Richard A
authors.initials: RA
authors.lastname: Campbell
authors.forename: Luke A
authors.initials: LA
authors.lastname: Clifton
authors.forename: Maximilian W A
authors.initials: MW
authors.lastname: Skoda
authors.forename: Olaf
authors.initials: O
authors.lastname: Soltwedel
authors.forename: Piero
authors.initials: P
authors.lastname: Baglioni
authors.forename: Tommy
authors.initials: T
authors.lastname: Nylander
mesh_terms: D004247:DNA / Q000737:chemistry*; D050091:Dendrimers / Q000737:chemistry*; D016503:Drug Delivery Systems; D008055:Lipids / Q000737:chemistry*; D009841:Oligonucleotides / Q000737:chemistry*; D011073:Polyamines / Q000737:chemistry*
chemical_list: D050091:Dendrimers; D008055:Lipids; D009841:Oligonucleotides; C531249:Poly(amidoamine); D011073:Polyamines; D004247:DNA