title: Early ultrasonographic diagnosis of placental mesenchymal dysplasia.
abstract: Placental mesenchymal dysplasia (PMD) is a rare pathology characterized by vascular anomalies, placentomegaly and grapelike vesicles resembling partial molar pregnancy. PMD is often associated with fetal growth restriction or intrauterine fetal demise. We report a case of an early diagnosis of PMD at 10 weeks' gestation, with a regular intrauterine growth and a fetal demise occurring at 31 week's gestation. The placenta showed aneurysmally dilated and tortuous vessels with luminal thrombosis. Even in presence of a regular fetal growth, a fetal demise may always occur, suggesting the option of an early heparin administration to reduce the risk of thrombosis of chorionic vessels.
authors.affiliation: Department of Surgical and Biomedical Sciences, Division of Obstetrics and Gynecology, University of Perugia, Perugia, Italy. sandro.gerli@unipg.it.
authors.forename: S
authors.initials: S
authors.lastname: Gerli
authors.forename: C
authors.initials: C
authors.lastname: Giordano
authors.forename: R
authors.initials: R
authors.lastname: Del Sordo
authors.forename: D
authors.initials: D
authors.lastname: Fratini
authors.forename: G C
authors.initials: GC
authors.lastname: Di Renzo
mesh_terms: D000328:Adult; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology; D005865:Gestational Age; D006801:Humans; D006828:Hydatidiform Mole / Q000175:diagnosis / Q000000981:diagnostic imaging; D010920:Placenta / Q000473:pathology; D010922:Placenta Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging*; D011247:Pregnancy; D014463:Ultrasonography