title: A review of syntheses of 1,5-disubstituted tetrazole derivatives.
abstract: This report provides a brief overview of the various representative literature procedures for the synthesis of 1,5-disubstituted tetrazoles (1,5-DSTs) and fused 1,5-disubstituted tetrazoles with more than 120 references. Most of the published methods for the synthesis of 1,5-DSTs include the use of nitriles, amides, thioamides, imidoyl chlorides, heterocumulenes, isocyanates, isothiocyanates, carbodiimides, ketenimines, ketones, amines, and alkenes as the starting materials. The transformation of 1- and 5-substituted tetrazoles into 1,5-DSTs is also covered in this report.
authors.affiliation: Department of Science, Babol University of Technology, Babol, Iran.
authors.forename: Afshin
authors.initials: A
authors.lastname: Sarvary
authors.forename: Ali
authors.initials: A
authors.lastname: Maleki
mesh_terms: D000577:Amides / Q000737:chemistry; D060326:Chemistry Techniques, Synthetic; D009570:Nitriles / Q000737:chemistry; D013777:Tetrazoles / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D000577:Amides; D009570:Nitriles; D013777:Tetrazoles; C045574:1H-tetrazole