title: [Application of HLAMatchmaker analysis eplets mismatch of renal transplant matching].
abstract: OBJECTIVE
  Eplets mismatch based on HLAMatchmaker software evaluates the clinical application of kidney transplantation.
  
  
  METHODS
  In 239 cases of renal transplant,merits of methods of the traditional HLA six antigen matcheing criteria, cross reaction groups standard and Eplets mismatch based on HLAMatchmaker standard were compared respectively.
  
  
  RESULTS
  The number of mismatchs with three methods in 239 cases, were grouped according to low-high mismatchs. The results revealed that HLAMatchmaker algorithm could significantly increase the number of low mismatchs group 54 (22.6%), compared with the HIA group 19(7.9%) and CREGs group 32 (13.4%). The comparison was discovered statistical significance among the three groups (P<0.001), so the comparison between each group was.
  
  
  CONCLUSIONS
  HLAMachmaker of donor-recipients matching, is a more efficient, time-saving and high sensitivity matching solution to allograft renal transplantation.
authors.forename: Xing
authors.initials: X
authors.lastname: Zhang
authors.forename: Xiao-Dong
authors.initials: XD
authors.lastname: Pan
authors.forename: Hui-Ying
authors.initials: HY
authors.lastname: Xu
authors.forename: Cun-Zao
authors.initials: CZ
authors.lastname: Wu
authors.forename: Yong
authors.initials: Y
authors.lastname: Cai
authors.forename: Peng
authors.initials: P
authors.lastname: Xia
authors.forename: Shao-Ling
authors.initials: SL
authors.lastname: Zheng
authors.forename: Yi-Rong
authors.initials: YR
authors.lastname: Yang
authors.forename: Bi-Cheng
authors.initials: BC
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006650:Histocompatibility Testing / Q000379:methods*; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D012984:Software; D014184:Transplantation, Homologous; D055815:Young Adult