title: Aerobic oxidative Mannich reaction promoted by catalytic amounts of stable radical cation salt.
abstract: A catalytic amount of triarylaminium salt is demonstrated to be an efficient initiator for oxidative Mannich reaction of tertiary amines and nonactivated ketones under mild neutral conditions. Air is essential for this reaction and acts as a terminal oxidant. Metal catalysts, acid or base additives, and stoichiometric amounts of chemical oxidants are all avoided in this methodology. Six examples of intramolecular cyclized products are also delivered.
authors.affiliation: Key Laboratory of Eco-Environment-Related Polymer Materials, Ministry of Education, College of Chemistry and Chemical Engineering, Northwest Normal University , Lanzhou, Gansu 730070, China.
authors.forename: Congde
authors.initials: C
authors.lastname: Huo
authors.forename: Mingxia
authors.initials: M
authors.lastname: Wu
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Jia
authors.forename: Haisheng
authors.initials: H
authors.lastname: Xie
authors.forename: Yong
authors.initials: Y
authors.lastname: Yuan
authors.forename: Jing
authors.initials: J
authors.lastname: Tang