title: [Current issues on the treatment of chronic constipation].
abstract: Chronic constipation is a very common clinical problem with its prevalence of up to 14% in the general population. It is not a life-threatening disease, but since patient's satisfaction to the treatment is known to be as low as 50%, chronic constipation still remains a clinically challenging problem. Fortunately, many new treatments have been introduced or are to be introduced in the near future. This article will review the basic concepts and the results of recent studies on the new treatments for chronic constipation.
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Kyoung Sup
authors.initials: KS
authors.lastname: Hong
authors.affiliation: Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Kee Wook
authors.initials: KW
authors.lastname: Jung
authors.affiliation: Institute for Digestive Research, Soonchunhyang University College of Medicine, Seoul, Korea.
authors.forename: Tae Hee
authors.initials: TH
authors.lastname: Lee
authors.affiliation: Departments of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
authors.forename: Bong Eun
authors.initials: BE
authors.lastname: Lee
authors.affiliation: Chonnam National University Medical School, Gwangju, Korea.
authors.forename: Sun-Young
authors.initials: SY
authors.lastname: Park
authors.affiliation: Dankook University College of Medicine, Cheonan, Korea.
authors.forename: Jeong Eun
authors.initials: JE
authors.lastname: Shin
authors.affiliation: Ewha Womans University School of Medicine, Seoul, Korea.
authors.forename: Seong-Eun
authors.initials: SE
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine and Institute for Medical Science, Keimyung University School of Medicine, Daegu, Korea.
authors.forename: Kyung Sik
authors.initials: KS
authors.lastname: Park
authors.affiliation: Department of Internal Medicine, Wonkwang University School of Medicine, Iksan, Korea.
authors.forename: Suck Chei
authors.initials: SC
authors.lastname: Choi
mesh_terms: D065101:Chloride Channel Agonists / Q000627:therapeutic use; D002908:Chronic Disease; D003248:Constipation / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D054368:Laxatives / Q000627:therapeutic use*; D011092:Polyethylene Glycols / Q000627:therapeutic use; D015995:Prevalence; D019936:Probiotics / Q000627:therapeutic use; D058828:Serotonin 5-HT4 Receptor Agonists / Q000627:therapeutic use
chemical_list: D065101:Chloride Channel Agonists; D054368:Laxatives; D058828:Serotonin 5-HT4 Receptor Agonists; D011092:Polyethylene Glycols
keywords: Constipation; Linaclotide; Lubiprostone; Prucalopride