title: [A case of gastric cancer with peritoneal dissemination successfully treated with low-dose S-1 or capecitabine chemotherapy for five years].
abstract: We report a case of gastric cancer with peritoneal dissemination that was successfully treated with low-dose S-1 or capecitabine chemotherapy over a 5-year period. In September 2007, distal gastrectomy was performed for treating gastric cancer with synchronous peritoneal dissemination in a 78-year-old man. Combination chemotherapy of S-1 and CDDP was administered after the surgical procedure. Following the completion of 9 courses, this regimen was discontinued owing to adverse events; therefore, S-1 (40-50mg/body/day) or capecitabine (1,800 mg/body/day) chemotherapy was initiated. S-1 or capecitabine were orally administered for 2 weeks, followed by a 2-week or 1-week interval, respectively; this regimen was continued for over 5 years. The patient died in June 2013.
authors.affiliation: Dept. of Surgery, Ohyodo General Hospital.
authors.forename: Shiro
authors.initials: S
authors.lastname: Ueda
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Minami
authors.forename: Yasuhito
authors.initials: Y
authors.lastname: Hara
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Nakamura
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D000069287:Capecitabine; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D004338:Drug Combinations; D017809:Fatal Outcome; D005472:Fluorouracil / Q000008:administration & dosage / Q000031:analogs & derivatives; D006801:Humans; D008297:Male; D010094:Oxonic Acid / Q000008:administration & dosage; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000556:secondary; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005641:Tegafur / Q000008:administration & dosage; D013997:Time Factors
chemical_list: D004338:Drug Combinations; D003841:Deoxycytidine; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D000069287:Capecitabine; D005472:Fluorouracil