title: Association between infertility treatment and symptoms of postpartum depression.
abstract: OBJECTIVE
  To examine the association between infertility treatment and subsequent symptoms of postpartum depression.
  
  
  METHODS
  Cross-sectional study.
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  Women who delivered live-born infants from 2009-2010.
  
  
  METHODS
  None.
  
  
  METHODS
  Odds of symptoms of postpartum depression.
  
  
  RESULTS
  Data were obtained from the Center for Disease Control and Prevention's Pregnancy Risk Assessment Monitoring System (PRAMS). Data on infertility treatment were available for 16 states in which mothers were sampled 2 to 4 months after delivery to complete the standardized PRAMS questionnaire. Infertility treatment status was as reported on the birth certificate. Maternal mental health was obtained via the maternal questionnaire. Data were analyzed in Stata 12.0 with sample weights to produce population-based estimates. Among the 42,614 women who resided in states in which infertility treatment data were collected, infertility treatment status was missing for 2,277 (5.3%) women. Among the 40,337 eligible women, 12.9% reported feeling down, depressed or sad, and 6.0% reported feeling hopeless. These women were considered to have symptoms of postpartum depression. Even after adjustment for confounders, there was no independent association between infertility treatment status and symptoms of postpartum depression. In contrast, having a child admitted to neonatal intensive care, smoking, experiencing a higher number of stressors in the 12 months before delivery, and a history of having prepregnancy mental health care were associated with an increased odds of having symptoms of postpartum depression.
  
  
  CONCLUSIONS
  In a population-based sample of U.S. women, conceiving with the help of infertility treatment did not increase the odds of experiencing symptoms of postpartum depression.
authors.affiliation: Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, College of Medicine, Ohio State University, Columbus, Ohio. Electronic address: courtney.lynch@osumc.edu.
authors.forename: Courtney D
authors.initials: CD
authors.lastname: Lynch
authors.affiliation: Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, College of Medicine, Ohio State University, Columbus, Ohio.
authors.forename: Mona R
authors.initials: MR
authors.lastname: Prasad
mesh_terms: D000293:Adolescent; D000328:Adult; D015984:Causality; D015897:Comorbidity; D003430:Cross-Sectional Studies; D019052:Depression, Postpartum / Q000453:epidemiology* / Q000523:psychology*; D005260:Female; D005307:Fertilization in Vitro / Q000523:psychology* / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D007247:Infertility, Female / Q000453:epidemiology* / Q000523:psychology* / Q000628:therapy; D008875:Middle Aged; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology / Q000523:psychology*; D013223:Statistics as Topic; D063189:Symptom Assessment; D014481:United States / Q000453:epidemiology; D055815:Young Adult
keywords: Infertility treatment; in vitro fertilization; postpartum depression