title: Pituitary stalk interruption syndrome: Case report of three cases with review of literature.
abstract: Pickardt syndrome (Pickardt-Fahlbusch syndrome) is a rare congenital syndrome characterized by tertiary hypothyroidism caused by the interruption of the portal veins between hypothalamus and adenohypophysis. Typical features of this syndrome are tertiary hypothyroidism with low thyroid stimulating hormone, hyperprolactinemia and other pituitary hormone deficiencies. Pituitary stalk interruption syndrome is characterized by a triad of thin or interrupted pituitary stalk, aplasia or hypoplasia of the anterior pituitary and absent or ectopic posterior pituitary (EPP) seen on magnetic resonance imaging (MRI). It is a congenital anomaly of pituitary whose exact prevalence is unknown. In some cases, it is restricted to EPP or pituitary stalk interruption. We are presenting the case history along with MRI finding of three children's who presented with short stature and delayed puberty.
authors.affiliation: Department of Endocrinology, LLRM Medical College, Meerut, India.
authors.forename: Manish
authors.initials: M
authors.lastname: Gutch
authors.affiliation: Department of Radiodiagnosis, SGPGI, Lucknow, Uttar Pradesh, India.
authors.forename: Sukriti
authors.initials: S
authors.lastname: Kumar
authors.affiliation: Department of Endocrinology, LLRM Medical College, Meerut, India.
authors.forename: Syed Mohd
authors.initials: SM
authors.lastname: Razi
authors.affiliation: Department of Endocrinology, LLRM Medical College, Meerut, India.
authors.forename: Sanjay
authors.initials: S
authors.lastname: Saran
authors.affiliation: Department of Endocrinology, LLRM Medical College, Meerut, India.
authors.forename: Keshav Kumar
authors.initials: KK
authors.lastname: Gupta
keywords: Delayed puberty; ectopic posterior pituitary; multiple pituitary hormones deficiency; pituitary stalk interruption syndrome