title: [Passive tactile stimulation and its clinical and neurophysiological repercussions (P300) in blind children with symptoms of attention deficit disorder].
abstract: BACKGROUND
  Tactile stimulation is key for the posterior brain re-organization activity and attention processes, however the impact of tactile stimulation on attention deficit disorder (ADD) in blind children remains unexplored.
  
  
  METHODS
  We carried out a study with children having or not ADD (four per group). The subjects have been exposed during six months to tactile stimulation protocol consisting in two daily sessions (morning and afternoon sessions) of 30 minutes each. We have measured the ability to detect an infrequent tactile stimulus, reaction time, latency of P300, sources of brain activity, and ADD clinical symptoms, before and after tactile training.
  
  
  RESULTS
  Passive tactile stimulation significantly improves ADD clinical symptoms, particularly attention, behavior and self-control of involuntary movements and tics. In addition, tactile stimulation changes the pattern of brain activity in ADD blind children inducing activity in frontal and occipital areas, which could be associated to a compensation of the attention deficit.
  
  
  CONCLUSIONS
  Passive tactile stimulation training may improve ADD clinical symptoms and can reorganize the pattern of brain activity in blind ADD children.
authors.forename: Isabel
authors.initials: I
authors.lastname: Serrano-Marugán
authors.forename: Begoña
authors.initials: B
authors.lastname: Herrera
authors.forename: Sara
authors.initials: S
authors.lastname: Romero
authors.forename: Ramón
authors.initials: R
authors.lastname: Nogales
authors.forename: Joaquín
authors.initials: J
authors.lastname: Poch-Broto
authors.forename: Javier
authors.initials: J
authors.lastname: Quintero
authors.affiliation: Universidad Complutense de Madrid. Facultad de Medicina, 28040 Madrid, Espana.
authors.forename: Tomás
authors.initials: T
authors.lastname: Ortiz
mesh_terms: D001289:Attention Deficit Disorder with Hyperactivity / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D001766:Blindness / Q000150:complications* / Q000503:physiopathology; D002648:Child; D004569:Electroencephalography; D018913:Event-Related Potentials, P300 / Q000502:physiology*; D005625:Frontal Lobe / Q000503:physiopathology; D006225:Hand; D006801:Humans; D021621:Imaging, Three-Dimensional; D059906:Neuroimaging / Q000379:methods*; D009778:Occipital Lobe / Q000503:physiopathology; D010812:Physical Stimulation; D011930:Reaction Time; D063189:Symptom Assessment; D014054:Tomography; D014110:Touch / Q000502:physiology