title: Cutaneous cytomegalovirus infection on multi dermatomal herpes zoster scars: an isotopic immune response.
abstract: As more patients with human immunodeficiency virus (HIV) are surviving, despite severe immune suppression, clinicians are faced with atypical manifestations of both common and uncommon dermatoses. A 30-year-old black South African woman presented with a 10-month history of multiple chronic ulcers appearing on a multidermatomal herpes zoster (HZ) scar. The woman was infected with HIV, and her CD4 count was 45 cells/μL. Histology and PCR revealed cytomegalovirus (CMV) infection. This case highlights an unusual presentation of cutaneous CMV occurring as an isotopic immune response on a pre-existing multidermatomal HZ scar.
authors.affiliation: Department of Dermatology, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa; Dermatology Unit, Department of Paediatrics and Child Health, University of Ilorin, Ilorin, Nigeria.
authors.forename: O S
authors.initials: OS
authors.lastname: Katibi
authors.forename: N C
authors.initials: NC
authors.lastname: Dlova
authors.forename: A
authors.initials: A
authors.lastname: Mosam
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000276:immunology*; D000328:Adult; D002908:Chronic Disease; D002921:Cicatrix / Q000276:immunology / Q000821:virology*; D003586:Cytomegalovirus Infections / Q000276:immunology*; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006562:Herpes Zoster / Q000150:complications*; D006801:Humans; D017193:Skin Diseases, Viral / Q000276:immunology*; D014456:Ulcer / Q000821:virology