title: Predictors for complications in pregnant women with heart disease, a retrospective study.
abstract: OBJECTIVE
  Evaluate the CARPREG score in predicting cardiac, obstetric, and neonatal complications in pregnant women with heart disease.
  
  
  METHODS
  This was a retrospective study between 2002 and 2011 at a tertiary care center and included 175 pregnant women with heart disease. Maternal and neonatal outcomes were assessed using Cardiac in Pregnancy Score (CARPREG), which included NYHA-class, systolic ejection fraction, left ventricular obstruction, and history of cardiac events.
  
  
  RESULTS
  Rheumatic heart disease (n = 116, 66.3%) was the predominant cardiac problem. CARPREG score was 0, 1, > 1 in 65.1%, 24.6%, and 10.3% pregnancies, respectively. Maternal cardiac events occurred in 27.4%. CARPREG score > or = 1 was associated with an increased rate of cardiac events [odds ratio (OR) 6.76, 95% confidence interval (CI) 3.26 to 14.01]. Fetal complications occurred 24.4%. Neonatal birth weight < 2,500 g was associated with CARPREG score > or = 1 (OR 2.57, 95% CI 1.29 to 5.11).
  
  
  CONCLUSIONS
  Maternal cardiac events can be predicted using CARPREG risk index. In Thai population, rheumatic heart disease was the most frequent form of cardiac problems in pregnant women.
authors.forename: Saowapark
authors.initials: S
authors.lastname: Chumpathong
authors.forename: Chuleeporn
authors.initials: C
authors.lastname: Sirithaweesit
authors.forename: Nuchsaroch
authors.initials: N
authors.lastname: Pechpaisit
authors.forename: Suwannee
authors.initials: S
authors.lastname: Suraseranivongse
authors.forename: Benno
authors.initials: B
authors.lastname: von Bormann
authors.forename: Vitaya
authors.initials: V
authors.lastname: Titapant
authors.forename: Sudta
authors.initials: S
authors.lastname: Parakkamodom
mesh_terms: D000328:Adult; D001724:Birth Weight; D005260:Female; D006331:Heart Diseases / Q000150:complications* / Q000453:epidemiology / Q000503:physiopathology; D006801:Humans; D007231:Infant, Newborn; D016017:Odds Ratio; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000453:epidemiology*; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D012214:Rheumatic Heart Disease / Q000150:complications* / Q000453:epidemiology; D012306:Risk; D055815:Young Adult