title: Pulmonary toxocariasis mimicking invasive aspergillosis in a patient with ulcerative colitis.
abstract: A 45-year-old-male who had underlying ulcerative colitis and presented with fever and dry cough. Initially, the patient was considered to have invasive aspergillosis due to a positive galactomannan assay. He was treated with amphotericin B followed by voriconazole. Nevertheless, the patient deteriorated clinically and radiographically. The lung biopsy revealed eosinophilic pneumonia, and ELISA for Toxocara antigen was positive, leading to a diagnosis of pulmonary toxocariasis. After a 10-day treatment course with albendazole and adjunctive steroids, the patient recovered completely without any sequelae. Pulmonary toxocariasis may be considered in patients with subacute or chronic pneumonia unresponsive to antibiotic agents, particularly in cases with eosinophilia.
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul 136-705, Korea.
authors.forename: Eun Jin
authors.initials: EJ
authors.lastname: Park
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul 136-705, Korea. ; Asian Pacific Influenza Institute (APII), Korea University College of Medicine, Seoul 136-705, Korea.
authors.forename: Joon Young
authors.initials: JY
authors.lastname: Song
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul 136-705, Korea.
authors.forename: Min Ju
authors.initials: MJ
authors.lastname: Choi
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul 136-705, Korea.
authors.forename: Ji Ho
authors.initials: JH
authors.lastname: Jeon
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul 136-705, Korea.
authors.forename: Jah-Yeon
authors.initials: JY
authors.lastname: Choi
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul 136-705, Korea.
authors.forename: Tae Un
authors.initials: TU
authors.lastname: Yang
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul 136-705, Korea.
authors.forename: Kyung Wook
authors.initials: KW
authors.lastname: Hong
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul 136-705, Korea. ; Asian Pacific Influenza Institute (APII), Korea University College of Medicine, Seoul 136-705, Korea.
authors.forename: Ji Yun
authors.initials: JY
authors.lastname: Noh
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul 136-705, Korea. ; Asian Pacific Influenza Institute (APII), Korea University College of Medicine, Seoul 136-705, Korea.
authors.forename: Hee Jin
authors.initials: HJ
authors.lastname: Cheong
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul 136-705, Korea. ; Asian Pacific Influenza Institute (APII), Korea University College of Medicine, Seoul 136-705, Korea.
authors.forename: Woo Joo
authors.initials: WJ
authors.lastname: Kim
mesh_terms: D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000947:Antigens, Helminth / Q000032:analysis; D003093:Colitis, Ulcerative / Q000150:complications*; D003937:Diagnosis, Differential; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D008168:Lung / Q000473:pathology; D008174:Lung Diseases, Parasitic / Q000175:diagnosis* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D055732:Pulmonary Aspergillosis / Q000175:diagnosis / Q000473:pathology; D013256:Steroids / Q000627:therapeutic use; D014119:Toxocara / Q000302:isolation & purification*; D014120:Toxocariasis / Q000175:diagnosis* / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D000871:Anthelmintics; D000893:Anti-Inflammatory Agents; D000947:Antigens, Helminth; D013256:Steroids; D015766:Albendazole
keywords: Toxocara canis; aspergillosis; eosinophilia; respiratory disorder; toxocariasis; ulcerative colitis