title: Neuromuscular complications of critical illness.
abstract: Neuromuscular sequelae are common in the critically ill. Critical illness polyneuropathy and critical illness myopathy are neuromuscular complications of sepsis or iatrogenic complications of treatments required in intensive care. This article discusses the diagnosis, treatment, and prognosis of these disorders based on a literature review. This review found that glycemic control, early mobilization, and judicious use of steroids and neuromuscular blocking agents are the primary approaches to reduce the incidence and severity of neuromuscular complications in affected patients.
authors.affiliation: Neurological Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA. Electronic address: osiasj@ccf.org.
authors.forename: Jules
authors.initials: J
authors.lastname: Osias
authors.affiliation: Neurological Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
authors.forename: Edward
authors.initials: E
authors.lastname: Manno
mesh_terms: D003422:Critical Care / Q000379:methods*; D016638:Critical Illness / Q000628:therapy*; D006801:Humans; D009135:Muscular Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D011115:Polyneuropathies / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D017410:Practice Guidelines as Topic; D011379:Prognosis; D018805:Sepsis / Q000150:complications*
keywords: Acute quadriplegic myopathy; Critical illness myopathy; Critical illness polyneuropathy; Neuromuscular disorders; Sepsis