title: Primary pure squamous cell carcinoma of the duodenum: a case report.
abstract: Primary pure squamous cell carcinoma of the duodenum is a very rare type of duodenal neoplasm and is more likely to be presented as a metastatic tumor. The literature offers little information on this subject and includes very few articles and case reports. Laboratory tests, CT and ultrasound examinations, x-rays and immunohistochemical markers assisted us in making this rare diagnosis of primary squamous cell carcinoma of the duodenum in a 47 year old female patient, who presented with weight loss and melena. The 8 cm duodenal tumor with pancreas invasion was resected by a cephalic duodenopancreatectomy. The pathology examination revealed a primary duodenal squamous cell carcinoma moderately differentiated (G2), invasive in the head of the pancreas, with keratinization, stage II B (pT4N0MxL0V0R0). Positive outcome after surgery was highlighted, no recurrence being registered at the 6 month CT scan follow-up.
authors.affiliation: Iuliu Hatieganu University of Medicine and Pharmacy, 3rd Surgical Clinic; Prof. O. Fodor Regional Institute of Gastroenterology and Hepatology , Cluj-Napoca, Romania.
authors.forename: Florin
authors.initials: F
authors.lastname: Graur
authors.affiliation: Iuliu Hatieganu University of Medicine and Pharmacy, 3rd Surgical Clinic; Prof. O. Fodor Regional Institute of Gastroenterology and Hepatology , Cluj-Napoca, Romania.
authors.forename: Emil
authors.initials: E
authors.lastname: Mois
authors.affiliation: Iuliu Hatieganu University of Medicine and Pharmacy, 3rd Surgical Clinic; Prof. O. Fodor Regional Institute of Gastroenterology and Hepatology , Cluj-Napoca, Romania. dr_nadim_alhajjar@yahoo.com.
authors.forename: Nadim
authors.initials: N
authors.lastname: Al Hajjar
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D004379:Duodenal Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D016577:Pancreaticoduodenectomy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D047368:Tumor Burden
chemical_list: D014408:Biomarkers, Tumor