title: Typhoid glomerulonephritis and intestinal perforation in a Nigerian child.
abstract: The number of children with renal complications following salmonella infection cannot be precisely defined in the sub-Saharan Africa due to scarcity of reliable data. We report a 3-year-old boy with glomerulonephritis secondary to typhoid infection and later intestinal perforation. He presented with fever, generalized body swelling, oliguria, coke- colored urine and hypertension and had been managed 3 weeks earlier for typhoid fever in a private hospital. Laboratory investigations showed proteinuria, hematuria with red cell casturia and azotemia. Abdominal X-ray done was suggestive of typhoid intestinal perforation that was confirmed at exploratory laparotomy. He was managed aggressively with antibiotics and was discharged on the 25 th day of admission. To the best of our knowledge, this is the first documented case report of acute glomerulonephritis and intestinal perforation as co-complications of salmonella infection in Nigeria.
authors.affiliation: Pediatric Nephrology Unit, University of Nigeria Teaching Hospital, Ituku Ozalla, Nigeria.
authors.forename: O I
authors.initials: OI
authors.lastname: Odetunde
authors.forename: O U
authors.initials: OU
authors.lastname: Ezenwosu
authors.forename: O A
authors.initials: OA
authors.lastname: Odetunde
authors.forename: J C
authors.initials: JC
authors.lastname: Azubuike
mesh_terms: D002675:Child, Preschool; D005921:Glomerulonephritis / Q000382:microbiology*; D006801:Humans; D007077:Ileal Diseases / Q000382:microbiology*; D007416:Intestinal Perforation / Q000382:microbiology*; D008297:Male; D009549:Nigeria; D014435:Typhoid Fever / Q000150:complications*