title: [Penis-preserving surgery in patients with primary penile urethral cancer].
abstract: BACKGROUND
  Primary urethral cancer in males is a rare entity with only approximately 800 cases described, which is why it is difficult to formulate evidence-based guidelines for treatment. For tumors in the pT2 stage with a localization distal to the membranous urethra, a penis-preserving operation can be carried out.
  
  
  METHODS
  In the period from November 2006 to February 2014 a total of 4 patients with primary urethral cancer underwent a penis-preserving urethral resection. The tumor characteristics and treatment results were collated retrospectively.
  
  
  RESULTS
  Of the four patients one had a transitional cell carcinoma of the mid-penile urethra in stage pT2 G2. In two out of the four patients a squamous cell carcinoma (PEC) was present in the mid-penile urethra in stages pT2 G2 and pT2 G3, respectively, with concomitant carcinoma in situ (CIS). The fourth patient had a PEC of the fossa terminalis in stage pT2 G2. Initially all patients underwent a penis-preserving resection. In one case, despite an initial R0 resection a local recurrence occurred and a complete penectomy was performed. Irradiation and lymphadenectomy were not carried out. At a mean follow-up of 37 months all patients are currently in complete remission.
  
  
  CONCLUSIONS
  Primary penile urethral cancer can be treated by a penis-preserving operation. Close follow-up is essential because recurrence can arise despite an initial R0 resection.
authors.affiliation: Kliniken Essen-Mitte, Henricistraße 92, 45136, Essen, Deutschland, m.maek@kliniken-essen-mitte.de.
authors.forename: M
authors.initials: M
authors.lastname: Maek
authors.forename: M
authors.initials: M
authors.lastname: Musch
authors.forename: G
authors.initials: G
authors.lastname: Arnold
authors.forename: D
authors.initials: D
authors.lastname: Kröpfl
mesh_terms: D000368:Aged; D006801:Humans; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D059351:Organ Sparing Treatments / Q000379:methods*; D010412:Penile Neoplasms / Q000473:pathology / Q000601:surgery*; D010413:Penis / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome; D014523:Urethral Neoplasms / Q000473:pathology / Q000601:surgery*; D013521:Urologic Surgical Procedures, Male / Q000379:methods*