title: Laterality and deep brain stimulation of the subthalamic nucleus: applying a dichotic listening task to patients treated for Parkinson's disease.
abstract: Ear advantage during a dichotic listening task tends to mirror speech lateralization. Previous studies in stroke patients have shown that lesions in the dominant hemisphere often seem to produce changes in ear advantage. In this study six Parkinson's disease (PD) patients treated for motor symptoms with deep brain stimulation (DBS) of the left subthalamic nucleus (STN) were tested preoperatively and at approximately 6 and 18 months postoperatively with a dichotic listening task. Results show a significant decline of the right ear advantage over time. In three of the patients a right ear advantage preoperatively changed to a left ear advantage 18 months postoperatively. This suggests the possibility that additional longitudinal studies of this phenomenon could serve as a model for understanding changes in indirect measures of speech lateralization in stroke patients.
authors.affiliation: a Department of Pharmacology and Clinical Neuroscience , Umeå University , Umeå , Sweden.
authors.forename: Rickard L
authors.initials: RL
authors.lastname: Sjöberg
authors.forename: Björn
authors.initials: B
authors.lastname: Häggström
authors.forename: Johanna
authors.initials: J
authors.lastname: Philipsson
authors.forename: Jan
authors.initials: J
authors.lastname: Linder
authors.forename: Marwan
authors.initials: M
authors.lastname: Hariz
authors.forename: Patric
authors.initials: P
authors.lastname: Blomstedt
mesh_terms: D001288:Attention; D001307:Auditory Perception / Q000502:physiology*; D046690:Deep Brain Stimulation; D004007:Dichotic Listening Tests; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000503:physiopathology* / Q000523:psychology / Q000534:rehabilitation; D020531:Subthalamic Nucleus / Q000503:physiopathology
keywords: aphasia; deep brain stimulation; dichotic listening; hemispheric dominance; subthalamic nucleus