title: A comparison of tissue prolapse with optical coherence tomography and intravascular ultrasound after drug-eluting stent implantation.
abstract: The aim of this study was to compare the detection rate of tissue prolapse (TP) in optical coherence tomography (OCT) and intravascular ultrasound (IVUS) after drug-eluting stent (DES) implantation and evaluate clinical implication of TP at 2 years after percutaneous coronary intervention. In spite of the superiority of OCT in the aspect of resolution when it was compared to IVUS, there was little data about the superiority of OCT in detecting TP. And there has been controversy about the clinical significance of TP. We enrolled 38 patients who treated with DES implantation. OCT and IVUS measurements were performed in stented segments immediately after percutaneous coronary intervention. We matched OCT and IVUS images one by one, and analyzed TP quantitatively in both measurements. Thirty patients (78.9 %) were followed-up for 2 years to evaluate clinical outcome of TP. TP was detected in 95 % of stented lesions by OCT and 45 % of stented lesions by IVUS among 40 stented lesions in 38 patients. The best cut-off values of the area, depth and burden of TP on OCT for the detection of TP on IVUS were 0.17 mm(2), 0.17 mm and 1.98 %, respectively. There was no statistically significant relation between TP and major adverse cardiac event during hospitalization and 2-year follow-up.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Daegu Catholic University, 2056-6 Daemyung-4 dong, Nam-gu, Daegu, Republic of Korea, drpearl0824@gmail.com.
authors.forename: Jihyun
authors.initials: J
authors.lastname: Sohn
authors.forename: Seung-Ho
authors.initials: SH
authors.lastname: Hur
authors.forename: In-Cheol
authors.initials: IC
authors.lastname: Kim
authors.forename: Yun-Kyeong
authors.initials: YK
authors.lastname: Cho
authors.forename: Hyung-Seob
authors.initials: HS
authors.lastname: Park
authors.forename: Hyuck-Jun
authors.initials: HJ
authors.lastname: Yoon
authors.forename: Chang-Wook
authors.initials: CW
authors.lastname: Nam
authors.forename: Yoon-Nyun
authors.initials: YN
authors.lastname: Kim
authors.forename: Kwon-Bae
authors.initials: KB
authors.lastname: Kim
mesh_terms: D000368:Aged; D003324:Coronary Artery Disease / Q000175:diagnosis / Q000628:therapy*; D023903:Coronary Restenosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology; D003331:Coronary Vessels / Q000000981:diagnostic imaging* / Q000473:pathology*; D054855:Drug-Eluting Stents; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects* / Q000295:instrumentation*; D011237:Predictive Value of Tests; D011391:Prolapse; D056910:Republic of Korea; D012189:Retrospective Studies; D013997:Time Factors; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional