title: Biosensors for hepatitis B virus detection.
abstract: A biosensor is an analytical device used for the detection of analytes, which combines a biological component with a physicochemical detector. Recently, an increasing number of biosensors have been used in clinical research, for example, the blood glucose biosensor. This review focuses on the current state of biosensor research with respect to efficient, specific and rapid detection of hepatitis B virus (HBV). The biosensors developed based on different techniques, including optical methods (e.g., surface plasmon resonance), acoustic wave technologies (e.g., quartz crystal microbalance), electrochemistry (amperometry, voltammetry and impedance) and novel nanotechnology, are also discussed.
authors.affiliation: Chun-Yan Yao, Wei-Ling Fu, Department of Laboratory Medicine, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
authors.forename: Chun-Yan
authors.initials: CY
authors.lastname: Yao
authors.affiliation: Chun-Yan Yao, Wei-Ling Fu, Department of Laboratory Medicine, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
authors.forename: Wei-Ling
authors.initials: WL
authors.lastname: Fu
mesh_terms: D000162:Acoustics; D000818:Animals; D015374:Biosensing Techniques / Q000295:instrumentation; D004279:DNA, Viral / Q000302:isolation & purification; D055664:Electrochemical Techniques; D004867:Equipment Design; D006509:Hepatitis B / Q000175:diagnosis* / Q000821:virology; D006510:Hepatitis B Antibodies / Q000302:isolation & purification; D006511:Hepatitis B Antigens / Q000302:isolation & purification; D006515:Hepatitis B virus / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D050997:Nanomedicine; D011237:Predictive Value of Tests; D020349:Surface Plasmon Resonance; D014159:Transducers; D019562:Viral Load
chemical_list: D004279:DNA, Viral; D006510:Hepatitis B Antibodies; D006511:Hepatitis B Antigens
keywords: Biosensor; Detection; Diagnosis; Hepatitis B virus; Quartz crystal microbalance