title: [Assessment of the curative effective of cochlear implantation in childer with GJB2-associated NSSNHL].
abstract: OBJECTIVE
  To analyze the curative effect of CI in children with GJB2-associated NSSNHL.
  
  
  METHODS
  The evaluations of curative effect with CI include auditory threshold, IT-MAIS/MAIS, CAP, SIR. MESP. The outcomes of 40 cases with GJB2-associated NSSNHI, were compared 80 patients with negative results of screening of gene mutation (control group).
  
  
  RESULTS
  In comparison with control group the auditory threshold in children with GJB2-associated NSSNIL is better, however had no significant difference in other tests (P > 0.05).
  
  
  CONCLUSIONS
  CI could he performed on children with GJB2-associated NSSNHL. Postoperative outcomes of hearing and speech were satisfied.
authors.forename: Chaochan
authors.initials: C
authors.lastname: Cai
authors.forename: Shasha
authors.initials: S
authors.lastname: Huang
authors.forename: Xue
authors.initials: X
authors.lastname: Gao
authors.forename: Bangqing
authors.initials: B
authors.lastname: Huang
authors.forename: Yongyi
authors.initials: Y
authors.lastname: Yuan
authors.forename: Guojian
authors.initials: G
authors.lastname: Wang
authors.forename: Dongyang
authors.initials: D
authors.lastname: Kang
authors.forename: Dongyi
authors.initials: D
authors.lastname: Han
authors.forename: Pu
authors.initials: P
authors.lastname: Dai
mesh_terms: D002648:Child; D002675:Child, Preschool; D019929:Cochlear Implantation; D000072259:Connexin 26; D017630:Connexins / Q000235:genetics; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000235:genetics / Q000601:surgery*; D006801:Humans; D007223:Infant; D008297:Male; D009154:Mutation; D016896:Treatment Outcome
chemical_list: D017630:Connexins; C000607042:GJB2 protein, human; D000072259:Connexin 26