title: Burkitt lymphoma with initial clinical presentation due to infiltration of the central nervous system and eye orbits.
abstract: BACKGROUND
  Burkitt lymphoma rarely affects the central nervous system and ocular region. Under these conditions, computed tomography and (particularly) magnetic resonance imaging of the skull increase the diagnostic accuracy, as they objectively show the topography of lesions and the effect of neoplasia on structures.
  
  
  METHODS
  We report here the case of a 17-year-old male whose initial clinical manifestations were related to neurological impairment and to the ocular musculature and ocular innervation. The diagnosis of Burkitt lymphoma with leukemization and infiltration of the central nervous system was confirmed.
  
  
  CONCLUSIONS
  In this case, it is important to recognize that the neuroimaging findings were fundamentally important in indicating the initial form of the disease and in directing the appropriate clinical management.
authors.affiliation: Postgraduate Programe in Medical Sciences, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Gustavo Bittencourt
authors.initials: GB
authors.lastname: Camilo
authors.affiliation: Postgraduate Programe in Medical Sciences, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Dequitier Carvalho
authors.initials: DC
authors.lastname: Machado
authors.affiliation: Department of Radiology, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Celso Estevão
authors.initials: CE
authors.lastname: de Oliveira
authors.affiliation: Department of Radiology, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Letícia da Silva
authors.initials: Lda S
authors.lastname: Lacerda
authors.affiliation: Department of Radiology, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Romulo Varella
authors.initials: RV
authors.lastname: de Oliveira
authors.affiliation: Department of Anatomic Pathology, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Monique de França
authors.initials: Mde F
authors.lastname: Silva
authors.affiliation: Postgraduate Programe in Medical Sciences, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Agnaldo José
authors.initials: AJ
authors.lastname: Lopes
mesh_terms: D000293:Adolescent; D001706:Biopsy; D001932:Brain Neoplasms / Q000175:diagnosis*; D002051:Burkitt Lymphoma / Q000175:diagnosis*; D002490:Central Nervous System / Q000000981:diagnostic imaging / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009918:Orbital Neoplasms / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed