title: Diagnosis and treatment of adrenal medullary hyperplasia: experience from 12 cases.
abstract: Objective. To dissect the characteristics of adrenal medullary hyperplasia (AMH) and share our experience of diagnosis and treatment of AMH. Methods. From 1999 to 2013, 12 cases of AMH have been pathologically diagnosed after operation in our hospital. The clinical characteristics, process of diagnosis, treatment, and prognosis during follow-up of all patients are summarized retrospectively. Results. Four cases were trended to be AMH and 6 cases were trended to be pheochromocytoma before operation; moreover, the other two patients were diagnosed accidentally. All patients, except for the patient with mucinous tubular and spindle cell carcinoma of left kidney by open surgery, experienced a smooth laparoscopic adrenalectomy, including 2 with radical nephrectomy, 10 of which experienced unilateral adrenalectomy, 1 was bilaterally partial adrenalectomy, and the remaining one was unilaterally complete removal and then 2/3 partially contralateral excision. After a medium follow-up of 6.5 years, it demonstrated a satisfactory outcome of 8 cured patients and 4 symptomatic improved patients. Conclusions. AMH presents a mimicking morphology and clinical manifestation with pheochromocytoma. Surgery could be the only effective choice for the treatment of AMH and showed a preferable prognosis after a quite long follow-up.
authors.affiliation: Department of Urology, West China Hospital, Sichuan University, No. 37 Guoxue Xiang, Chengdu 610041, China.
authors.forename: Lu
authors.initials: L
authors.lastname: Yang
authors.affiliation: Department of Urology, West China Hospital, Sichuan University, No. 37 Guoxue Xiang, Chengdu 610041, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Gao
authors.affiliation: Department of Urology, West China Hospital, Sichuan University, No. 37 Guoxue Xiang, Chengdu 610041, China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Lv
authors.affiliation: Department of Urology, West China Hospital, Sichuan University, No. 37 Guoxue Xiang, Chengdu 610041, China.
authors.forename: Shengqiang
authors.initials: S
authors.lastname: Qian
authors.affiliation: Department of Urology, West China Hospital, Sichuan University, No. 37 Guoxue Xiang, Chengdu 610041, China.
authors.forename: Siyuan
authors.initials: S
authors.lastname: Bu
authors.affiliation: Department of Urology, West China Hospital, Sichuan University, No. 37 Guoxue Xiang, Chengdu 610041, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wei
authors.affiliation: Department of Urology, West China Hospital, Sichuan University, No. 37 Guoxue Xiang, Chengdu 610041, China.
authors.forename: Jiuhong
authors.initials: J
authors.lastname: Yuan
authors.affiliation: Department of Urology, People's Hospital of Deyang City, Deyang 618000, China.
authors.forename: Tianyong
authors.initials: T
authors.lastname: Fan