title: Testicular myeloid sarcoma: a rare manifestation of acute myeloid leukemia in an infant.
abstract: Myeloid sarcoma manifesting in the testis is rare and may occur concomitantly with bone marrow disease or as a separate entity. We describe our experience with a 6-month-old boy who presented with painless scrotal swelling and was found to have bilateral testicular masses on ultrasonography. The patient underwent unilateral radical inguinal orchiectomy. Surgical pathology revealed myeloid sarcoma of the testicle. He developed peripheral blood involvement 1 week postoperatively. Bone marrow biopsy showed acute myeloid leukemia. He is in remission after 2 cycles of induction chemotherapy, local radiation therapy, and allogeneic bone marrow transplantation.
authors.affiliation: Department of Urology, The Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH. Electronic address: tranc@ccf.org.
authors.forename: Christine N
authors.initials: CN
authors.lastname: Tran
authors.affiliation: Department of Clinical Pathology, Pathology and Laboratory Medicine Institute, Cleveland Clinic Foundation, Cleveland, OH.
authors.forename: Angela M B
authors.initials: AM
authors.lastname: Collie
authors.affiliation: Department of Pediatric Hematology and Oncology, Cleveland Clinic Foundation, Cleveland, OH.
authors.forename: Aron
authors.initials: A
authors.lastname: Flagg
authors.affiliation: Department of Urology, The Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH.
authors.forename: Audrey
authors.initials: A
authors.lastname: Rhee
mesh_terms: D006801:Humans; D007223:Infant; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000175:diagnosis; D008297:Male; D023981:Sarcoma, Myeloid / Q000209:etiology*; D013736:Testicular Neoplasms / Q000209:etiology*