title: The enhancing effect of fucoidan derived from Undaria pinnatifida on immunoglobulin production by mouse spleen lymphocytes.
abstract: In this study, we revealed that a Mekabu (Udaria pinnantifida) extract enhanced immunoglobulin (Ig) production of mouse spleen lymphocytes. Furthermore, it was suggested that water-soluble and high molecular weight ingredients in the Mekabu extract have significant enhancing effect on Ig production. Therefore, fucoidan was estimated as the active component.
authors.affiliation: a Faculty of Agriculture , Kyushu University , Fukuoka , Japan.
authors.forename: Mika
authors.initials: M
authors.lastname: Takai
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Miyazaki
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Tachibana
authors.forename: Koji
authors.initials: K
authors.lastname: Yamada
mesh_terms: D000818:Animals; D005260:Female; D007136:Immunoglobulins / Q000096:biosynthesis*; D008214:Lymphocytes / Q000187:drug effects* / Q000378:metabolism*; D051379:Mice; D008970:Molecular Weight; D011134:Polysaccharides / Q000737:chemistry / Q000494:pharmacology*; D013154:Spleen / Q000276:immunology*; D044648:Undaria / Q000737:chemistry*
chemical_list: D007136:Immunoglobulins; D011134:Polysaccharides; C007789:fucoidan
keywords: Mekabu (Undaria pinnatifida); fucoidan; immunoglobulin (Ig); mouse spleen lymphocytes; water extract