title: [Managing of platelet transfusion refractoriness of haematological malignancies. Experience IPC-EFSAM].
abstract: The platelet refractoriness is a complication of transfusion treatments potentially dramatic in onco-haematology. Chemo-treatment of haematological malignancies or packs of allogeneic bone marrow transplants require iterative platelet transfusion requirements. The discovery of a platelet refractoriness along with its support should be the most reactive as possible but also adapted to the cause. In the case of allo-immunization, it may be expected. The purpose of this presentation is to recall the different etiologies and perform a feedback on the support transfusion platelet of onco-haematology adult patients at Institut Paoli-Calmettes (IPC) in partnership with the EFSAM.
authors.affiliation: Établissement français du sang Alpes-Méditerranée (EFSAM), 149, boulevard Baille, 13992 Marseille cedex 05, France.
authors.forename: I
authors.initials: I
authors.lastname: Dettori
authors.affiliation: Centre de lutte contre le cancer, Institut Paoli-Calmettes (IPC), cellule d'hémovigilance, 232, boulevard Sainte-Marguerite, 13009 Marseille, France. Electronic address: patrickldq@yahoo.fr.
authors.forename: P
authors.initials: P
authors.lastname: Ladaique
mesh_terms: D000047:Academies and Institutes / Q000458:organization & administration; D064591:Allografts / Q000276:immunology; D016824:Antigens, Human Platelet / Q000276:immunology; D001771:Blood Banks; D001792:Blood Platelets / Q000276:immunology*; D016026:Bone Marrow Transplantation; D019468:Disease Management; D005602:France; D019337:Hematologic Neoplasms / Q000276:immunology* / Q000628:therapy; D006405:Hematology; D006748:Hospital Departments; D006801:Humans; D007114:Immunization; D007373:Interinstitutional Relations; D007518:Isoantibodies / Q000276:immunology*; D008495:Medical Oncology; D017713:Platelet Transfusion / Q000009:adverse effects; D013154:Spleen / Q000503:physiopathology; D013921:Thrombocytopenia / Q000209:etiology / Q000276:immunology / Q000628:therapy*
chemical_list: D016824:Antigens, Human Platelet; D007518:Isoantibodies
keywords: Allo-immunisation anti-HLA; Allo-immunisation anti-HPA; HLA alloimmunisation; HPA alloimmunisation; Haematological malignancies; Hémopathies malignes; Platelet refractoriness; État réfractaire