title: Review of rapid diagnostic tests used by antimicrobial stewardship programs.
abstract: Rapid microbiologic tests provide opportunities for antimicrobial stewardship programs to improve antimicrobial use and clinical and economic outcomes. Standard techniques for identification of organisms require at least 48-72 hours for final results, compared with rapid diagnostic tests that provide final organism identification within hours of growth. Importantly, rapid microbiologic tests are considered "game changers" and represent a significant advancement in the management of infectious diseases. This review focuses on currently available rapid diagnostic tests and, importantly, the impact of rapid testing in combination with antimicrobial stewardship on patient outcomes.
authors.affiliation: Department of Pharmacy, The Ohio State University Wexner Medical Center, Columbus.
authors.forename: Karri A
authors.initials: KA
authors.lastname: Bauer
authors.affiliation: Department of Pharmacy Department of Pathology and Genomic Medicine, Houston Methodist Hospital Department of Center for Outcomes Research, Houston Methodist Research Institute, Texas.
authors.forename: Katherine K
authors.initials: KK
authors.lastname: Perez
authors.affiliation: Division of Infectious Diseases, Portland Veterans Affairs Medical Center, Oregon.
authors.forename: Graeme N
authors.initials: GN
authors.lastname: Forrest
authors.affiliation: Department of Pharmacy, The Ohio State University Wexner Medical Center, Columbus.
authors.forename: Debra A
authors.initials: DA
authors.lastname: Goff
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D003141:Communicable Diseases / Q000188:drug therapy / Q000382:microbiology; D003955:Diagnostic Tests, Routine; D004363:Drug Utilization; D006801:Humans; D008826:Microbial Sensitivity Tests; D058889:Molecular Typing; D016896:Treatment Outcome
chemical_list: D000890:Anti-Infective Agents
keywords: antimicrobial stewardship; costs; outcomes; rapid diagnostic test