title: Therapeutic approaches to gastroesophageal junction adenocarcinomas.
abstract: The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on the distinction between adenocarcinomas above, below, or within the gastroesophageal junction; combined modality therapy; tumor markers for use in personalized medicine; PET-CT and endoscopic biopsies in the evaluation of response to neoadjuvant chemoradiation therapy; a standardized grading system for tumor regression in squamous cell cancer and adenocarcinoma; the experimental basis for new approaches to medical treatment; the criteria measuring response in esophageal cancer; and the impact of novel imaging on staging and response assessment.
authors.affiliation: Department of Surgery, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands.
authors.forename: Rachel L G M
authors.initials: RL
authors.lastname: Blom
authors.forename: Tatiana
authors.initials: T
authors.lastname: Bogush
authors.forename: Björn L D M
authors.initials: BL
authors.lastname: Brücher
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Chang
authors.forename: Mikhail
authors.initials: M
authors.lastname: Davydov
authors.forename: Evgeny
authors.initials: E
authors.lastname: Dudko
authors.forename: Trevor
authors.initials: T
authors.lastname: Leong
authors.forename: Boris
authors.initials: B
authors.lastname: Polotsky
authors.forename: Paul E
authors.initials: PE
authors.lastname: Swanson
authors.forename: Peter S N
authors.initials: PS
authors.lastname: van Rossum
authors.forename: Jelle P
authors.initials: JP
authors.lastname: Ruurda
authors.forename: Xavier
authors.initials: X
authors.lastname: Sagaert
authors.forename: Sergei
authors.initials: S
authors.lastname: Tjulandin
authors.forename: Marie-Celine
authors.initials: MC
authors.lastname: Schraepen
authors.forename: Meindert N
authors.initials: MN
authors.lastname: Sosef
authors.forename: Richard
authors.initials: R
authors.lastname: van Hillegersberg
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy*; D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D014408:Biomarkers, Tumor / Q000235:genetics; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy*; D004943:Esophagogastric Junction / Q000473:pathology*; D006801:Humans; D010297:Paris; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy*
chemical_list: D014408:Biomarkers, Tumor
keywords: OESO; PET-CT; combined modality therapy; gastroesophageal junction; tumor grading; tumor markers; tumor regression