title: Dilated cardiomyopathy with left ventricular thrombi as a presenting feature of Cushing disease.
abstract: We report on a 20-year-old man with dilated cardiomyopathy and intracardiac thrombi associated with Cushing disease (CD). The patient presented with symptomatic heart failure. Follow-up echocardiography showed 2 thrombi in the apex of the left ventricle, which resolved after intravenous heparin therapy. The patient was first treated symptomatically, and then trans-sphenoidal adenomectomy was performed. Although cortisol excess alone may not be sufficient to produce severe cardiomyopathy, progressive improvement of cardiac function was observed within 3 years after surgery.
authors.affiliation: Department of Internal Medicine, Presbyterian Medical Center, Jeonju, Republic of Korea.
authors.forename: Ji Hye
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Gunsan Medical Center, Gunsan, Republic of Korea.
authors.forename: So Young
authors.initials: SY
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Chonbuk National University Medical School, Research Institute of Clinical Medicine, Jeonju, Republic of Korea. Electronic address: parkjh@jbnu.ac.kr.
authors.forename: Ji Hyun
authors.initials: JH
authors.lastname: Park
mesh_terms: D002311:Cardiomyopathy, Dilated / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D004452:Echocardiography; D006331:Heart Diseases / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008297:Male; D047748:Pituitary ACTH Hypersecretion / Q000150:complications*; D013902:Radiography, Thoracic; D013927:Thrombosis / Q000175:diagnosis / Q000209:etiology*; D055815:Young Adult