title: Long-term evaluation of periodontal parameters and implant outcomes in periodontally compromised patients: a systematic review.
abstract: BACKGROUND
  The aim of this systematic review is to evaluate the long-term outcomes of patients with periodontitis submitted to periodontal therapy/maintenance and implant placement.
  
  
  METHODS
  Studies reporting clinical and/or long-term implant outcomes from partially edentulous patients with periodontitis who were treated and followed periodontal maintenance for ≥5 years were considered eligible for the review. Screening of the articles, data extraction, and quality assessment were conducted independently and in duplicate.
  
  
  RESULTS
  Search of MEDLINE, EMBASE, and CENTRAL databases resulted in 959 papers, and of them 931 were excluded after title/abstract assessment. The full texts of 28 potentially eligible publications were screened, but only 10 studies met inclusion criteria. Most of the included studies (77.8%) presented a medium/high methodologic quality. The results demonstrated that patients with a diagnosis of periodontitis had satisfactory implant outcomes. Implant survival was high (92.1%) within studies reporting 10 years of follow-up. Parameters related to probing depth, clinical attachment level, and bone loss around teeth increased the occurrence of peri-implantitis and implant loss. Non-attendance to periodontal maintenance and smoking habits were also associated with less favorable implant outcomes.
  
  
  CONCLUSIONS
  This systematic review confirmed that implant therapy can be successfully used in patients with a diagnosis of periodontitis who underwent proper therapy and regular periodontal maintenance. Residual pockets, non-attendance to the periodontal maintenance program, and smoking were considered to be negative factors for the long-term implant outcomes.
authors.affiliation: Division of Periodontics, Department of Prosthodontics, School of Dentistry at Bauru (Faculty of Odontology of Bauru), University of São Paulo, Bauru, São Paulo, Brazil.
authors.forename: Mariana Schutzer
authors.initials: MS
authors.lastname: Zangrando
authors.forename: Carla Andreotti
authors.initials: CA
authors.lastname: Damante
authors.forename: Adriana Campos
authors.initials: AC
authors.lastname: Sant'Ana
authors.forename: Maria Lúcia
authors.initials: ML
authors.lastname: Rubo de Rezende
authors.forename: Sebastião Luiz
authors.initials: SL
authors.lastname: Greghi
authors.forename: Leandro
authors.initials: L
authors.lastname: Chambrone
mesh_terms: D015921:Dental Implants; D006801:Humans; D007576:Jaw, Edentulous, Partially / Q000534:rehabilitation; D008137:Longitudinal Studies; D010352:Patient Dropouts; D057873:Peri-Implantitis / Q000150:complications; D010514:Periodontal Pocket / Q000150:complications; D010518:Periodontitis / Q000150:complications* / Q000628:therapy; D012907:Smoking / Q000009:adverse effects; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D015921:Dental Implants
keywords: Dental implants; osseointegration; peri-implantitis; periodontitis; systematic review