title: Molecular design and synthesis of novel salicyl glycoconjugates as elicitors against plant diseases.
abstract: A new series of salicyl glycoconjugates containing hydrazide and hydrazone moieties were designed and synthesized. The bioassay indicated that the novel compounds had no in vitro fungicidal activity but showed significant in vivo antifungal activity against the tested fungal pathogens. Some compounds even had superior activity than the commercial fungicides in greenhouse trial. The results of RT-PCR analysis showed that the designed salicyl glycoconjugates could induce the expression of LOX1 and Cs-AOS2, which are the specific marker genes of jasmonate signaling pathway, to trigger the plant defense resistance.
authors.affiliation: Guangdong Province Key Laboratory of Microbial Signals and Disease Control, Department of Plant Pathology, College of Natural Resource and Environment, South China Agricultural University, Guangzhou, China; Department of Nanobiology, Graduate School of Advanced Integration Science, Chiba University, Chiba, Japan; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China.
authors.forename: Zining
authors.initials: Z
authors.lastname: Cui
authors.affiliation: Department of Environment Science for Bioproduction, Graduate School of Horticulture, Chiba University, Chiba, Japan.
authors.forename: Jun
authors.initials: J
authors.lastname: Ito
authors.affiliation: Department of Nanobiology, Graduate School of Advanced Integration Science, Chiba University, Chiba, Japan.
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Dohi
authors.affiliation: Department of Environment Science for Bioproduction, Graduate School of Horticulture, Chiba University, Chiba, Japan.
authors.forename: Yoshimiki
authors.initials: Y
authors.lastname: Amemiya
authors.affiliation: Department of Nanobiology, Graduate School of Advanced Integration Science, Chiba University, Chiba, Japan.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Nishida
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D005659:Fungicides, Industrial / Q000494:pharmacology*; D006001:Glycoconjugates / Q000494:pharmacology; D006834:Hydrazines / Q000494:pharmacology*; D015394:Molecular Structure; D010935:Plant Diseases / Q000382:microbiology*; D010944:Plants / Q000187:drug effects*
chemical_list: D000935:Antifungal Agents; D005659:Fungicides, Industrial; D006001:Glycoconjugates; D006834:Hydrazines; C000687:salicyl hydrazide