title: Bullous pyoderma gangrenosum associated with pancytopenia of unknown origin.
abstract: Pyoderma gangrenosum (PG) is a neutrophilic dermatosis of unknown origin. Clinically it starts with a pustule, nodule or bulla that rapidly progresses and turns into a painful ulcer with raised, undermined borders. The etiopathogenesis of PG remains unknown. However it is frequently associated with systemic diseases such as inflammatory bowel disease (IBD), haematological disorders or arthritis. The latest multicentric retrospective analysis published by Ghazal et al. shows that anaemia has been observed very often in German patients suffering from PG (in 45.6% of 259) so this disorder is supposed to be a possible cofactor in the pathogenesis of PG. According to its progressive course, patients require intensive diagnostic procedures and rapid initiation of the treatment. In this article, we report a case of bullous pyoderma gangrenosum in association with pancytopenia of unknown origin, according to its diagnostic and therapeutic difficulties.
authors.affiliation: Medical Students' Research Association at Department of Dermatology, Venereology and Paediatric Dermatology, Medical University of Lublin, Poland. Scientific supervisor: Prof. Dorota Krasowska MD, PhD.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Wolska
authors.affiliation: Department of Dermatology, Venereology and Paediatric Dermatology, Medical University of Lublin, Poland. Head of Department: Prof. Grażyna Chodorowska MD, PhD.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Michalska-Jakubus
authors.affiliation: Department of Dermatology, Venereology and Paediatric Dermatology, Medical University of Lublin, Poland. Head of Department: Prof. Grażyna Chodorowska MD, PhD.
authors.forename: Joanna
authors.initials: J
authors.lastname: Pucuła
authors.affiliation: Department of Dermatology, Venereology and Paediatric Dermatology, Medical University of Lublin, Poland. Head of Department: Prof. Grażyna Chodorowska MD, PhD.
authors.forename: Grażyna
authors.initials: G
authors.lastname: Chodorowska
authors.affiliation: Department of Internal Medicine, Medical University of Lublin, Poland. Head of Department: Prof. Jerzy Mosiewicz MD, PhD.
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Dzida
authors.affiliation: Department of Internal Medicine, Medical University of Lublin, Poland. Head of Department: Prof. Jerzy Mosiewicz MD, PhD.
authors.forename: Jerzy
authors.initials: J
authors.lastname: Mosiewicz
authors.affiliation: Department of Internal Medicine, Medical University of Lublin, Poland. Head of Department: Prof. Jerzy Mosiewicz MD, PhD.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Prystupa
authors.affiliation: Department of Haematology-Oncology, Medical University of Lublin, Poland. Head of Department: Prof. Anna Dmoszyńska MD, PhD.
authors.forename: Monika
authors.initials: M
authors.lastname: Podhorecka
authors.affiliation: Medical Students' Research Association at Department of Dermatology, Venereology and Paediatric Dermatology, Medical University of Lublin, Poland. Scientific supervisor: Prof. Dorota Krasowska MD, PhD ; Department of Dermatology, Venereology and Paediatric Dermatology, Medical University of Lublin, Poland. Head of Department: Prof. Grażyna Chodorowska MD, PhD.
authors.forename: Dorota
authors.initials: D
authors.lastname: Krasowska
keywords: bullous pyoderma gangrenosum; pancytopenia