title: Transcatheter mitral valve implantation (TMVI) using the Edwards FORTIS device.
abstract: Transcatheter aortic valve implantation (TAVI) has demonstrated the feasibility of treating valvular heart disease with transcatheter therapy. On the back of this success, various transcatheter concepts are being evaluated to treat other valvular disease, especially mitral regurgitation (MR). The concepts currently approved to treat MR replicate surgical mitral valve repair. However, most of them cannot eliminate MR completely. Similar to TAVI, a transcatheter mitral valve implantation may provide a valuable alternative. The FORTIS transcatheter mitral valve (Edwards Lifesciences, Irvine, CA, USA) is a self-expanding device implanted via a transapical approach. We describe our experience and early results in the first five patients treated on compassionate grounds. We also describe the details of the device, selection criteria and technical details of implantation.
authors.affiliation: Department of Cardiothoracic Surgery and Cardiology, St. Thomas' Hospital, London, United Kingdom.
authors.forename: Vinayak
authors.initials: V
authors.lastname: Bapat
authors.forename: Lutz
authors.initials: L
authors.lastname: Buellesfeld
authors.forename: Mark D
authors.initials: MD
authors.lastname: Peterson
authors.forename: Jane
authors.initials: J
authors.lastname: Hancock
authors.forename: David
authors.initials: D
authors.lastname: Reineke
authors.forename: Chris
authors.initials: C
authors.lastname: Buller
authors.forename: Thierry
authors.initials: T
authors.lastname: Carrel
authors.forename: Fabien
authors.initials: F
authors.lastname: Praz
authors.forename: Ronal
authors.initials: R
authors.lastname: Rajani
authors.forename: Neil
authors.initials: N
authors.lastname: Fam
authors.forename: Han
authors.initials: H
authors.lastname: Kim
authors.forename: Simon
authors.initials: S
authors.lastname: Redwood
authors.forename: Christopher
authors.initials: C
authors.lastname: Young
authors.forename: Christopher
authors.initials: C
authors.lastname: Munns
authors.forename: Stephan
authors.initials: S
authors.lastname: Windecker
authors.forename: Martyn
authors.initials: M
authors.lastname: Thomas
mesh_terms: D000818:Animals; D001705:Bioprosthesis; D002417:Cattle; D057510:Endovascular Procedures / Q000295:instrumentation* / Q000379:methods; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D008943:Mitral Valve; D008944:Mitral Valve Insufficiency / Q000601:surgery