title: Sleep in mother and child dyads during treatment for pediatric acute lymphoblastic leukemia.
abstract: OBJECTIVE
  To compare the sleep of children with acute lymphoblastic leukemia (ALL) during maintenance treatment with controls and to measure the effect on maternal sleep.
  
  
  METHODS
  Comparative, descriptive.
  
  
  METHODS
  Pediatric oncology clinic and communities in Colorado.
  
  
  METHODS
  26 dyads of mothers and children with ALL and matched controls.
  
  
  METHODS
  Mothers completed insomnia severity, mood, and stress questionnaires and wore a wrist actigraph, and mothers and children completed a seven-day sleep diary.
  
  
  METHODS
  Mother and child sleep parameters (e.g., total sleep time, sleep latency, sleep efficiency, awakenings); maternal insomnia severity, mood, and stress; child sleep habits.
  
  
  RESULTS
  Mothers of children with ALL reported greater insomnia compared to controls, which was correlated with anxiety, depressive symptoms, and stress. Maternal groups did not differ on diary- and actigraph-measured sleep outcomes; both groups experienced sleep fragmentation. Children with ALL took longer to fall asleep and had more variable sleep patterns.
  
  
  CONCLUSIONS
  Actigraph and sleep diary data indicated adequate maternal sleep duration and sleep latency. Self-reported insomnia severity in mothers of children with ALL suggested sleep fragmentation that may be undetected by these measures.
  
  
  CONCLUSIONS
  Oncology nurses are in a unique position to identify sleep problems in mothers and children with ALL, which may lead to recommendations for improved sleep and referrals for treatment.
authors.affiliation: College of Nursing, University of Colorado Anschutz Medical Campus in Aurora.
authors.forename: Ellyn E
authors.initials: EE
authors.lastname: Matthews
authors.affiliation: College of Nursing, University of Colorado Anschutz Medical Campus in Aurora.
authors.forename: Madalynn
authors.initials: M
authors.lastname: Neu
authors.affiliation: College of Nursing, University of Colorado Anschutz Medical Campus in Aurora.
authors.forename: Paul F
authors.initials: PF
authors.lastname: Cook
authors.affiliation: Department of Pediatrics, University of Colorado Anschutz Medical Campus in Aurora.
authors.forename: Nancy
authors.initials: N
authors.lastname: King
mesh_terms: D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D009035:Mothers; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy; D012890:Sleep; D007319:Sleep Initiation and Maintenance Disorders / Q000453:epidemiology*
keywords: acute lymphoblastic leukemia; caregivers; insomnia; maintenance treatment; pediatric cancer; sleep disturbance