title: [Invasive orbital aspergillosis: Rare but important differential diagnosis in the case of immunosuppression].
abstract: Invasive aspergillosis originating from the paranasal sinuses is a rare disease that is associated with high mortality rates. We report on a 77-year-old patient with myelodysplastic syndrome and progressive left-sided proptosis persisting for 5 days. Antibiotic therapy and endonasal orbital decompression yielded insufficient improvement. Only upon application of complementary antifungal therapy was remission observed. Rapid diagnosis and treatment are essential in order to prevent life-threatening complications.
authors.affiliation: Klinik für Hals-, Nasen-, Ohrenheilkunde, Kopf- und Halschirurgie, Plastische Operationen, Helios Klinikum Bad Saarow, Pieskower Str. 33, 15526, Bad Saarow, Deutschland, susann.roos@helios-kliniken.de.
authors.forename: S
authors.initials: S
authors.lastname: Roos
authors.forename: F
authors.initials: F
authors.lastname: Bast
authors.forename: T
authors.initials: T
authors.lastname: Schrom
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000139:chemically induced* / Q000175:diagnosis* / Q000188:drug therapy; D003937:Diagnosis, Differential; D015821:Eye Infections, Fungal / Q000139:chemically induced* / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D008297:Male; D035583:Rare Diseases; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D007166:Immunosuppressive Agents