title: Green tea consumption affects cognitive dysfunction in the elderly: a pilot study.
abstract: Green tea is known to have various health benefits for humans. However, the effect of green tea consumption on cognitive dysfunction remains to be clinically verified. We conducted a clinical study to investigate the effects of green tea consumption on cognitive dysfunction. Twelve elderly nursing home residents with cognitive dysfunction (Mini-Mental State Examination Japanese version (MMSE-J) score: <28) participated in the study (2 men, 10 women; mean age, 88 years). The participants consumed green tea powder 2 g/day for 3 months. After three months of green tea consumption, the participants' MMSE-J scores were significantly improved (before, 15.3 ± 7.7; after, 17.0 ± 8.2; p = 0.03). This result suggests that green tea consumption may be effective in improving cognitive function or reducing the progression of cognitive dysfunction; however, long-term large-scale controlled studies are needed to further clarify the effect.
authors.affiliation: Department of Drug Evaluation and Informatics, Graduate School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan. s13403@u-shizuoka-ken.ac.jp.
authors.forename: Kazuki
authors.initials: K
authors.lastname: Ide
authors.affiliation: Department of Drug Evaluation and Informatics, Graduate School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan. hyamada@u-shizuoka-ken.ac.jp.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yamada
authors.affiliation: White Cross Nursing Home, 2-26-1 Suwa-cho, Higashimurayama, Tokyo 189-0021, Japan. hide1844@wa2.so-net.ne.jp.
authors.forename: Norikata
authors.initials: N
authors.lastname: Takuma
authors.affiliation: Department of Drug Evaluation and Informatics, Graduate School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan. parkmjjp@yahoo.co.jp.
authors.forename: Mijong
authors.initials: M
authors.lastname: Park
authors.affiliation: Department of Drug Evaluation and Informatics, Graduate School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan. m08129@u-shizuoka-ken.ac.jp.
authors.forename: Noriko
authors.initials: N
authors.lastname: Wakamiya
authors.affiliation: Central Research Institute, ITO EN, Ltd., 21 Mekami, Makinohara, Shizuoka 421-0516, Japan. j-nakase@itoen.co.jp.
authors.forename: Junpei
authors.initials: J
authors.lastname: Nakase
authors.affiliation: Central Research Institute, ITO EN, Ltd., 21 Mekami, Makinohara, Shizuoka 421-0516, Japan. y-ukawa@itoen.co.jp.
authors.forename: Yuuichi
authors.initials: Y
authors.lastname: Ukawa
authors.affiliation: Central Research Institute, ITO EN, Ltd., 21 Mekami, Makinohara, Shizuoka 421-0516, Japan. y-sagesaka@itoen.co.jp.
authors.forename: Yuko M
authors.initials: YM
authors.lastname: Sagesaka
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003071:Cognition / Q000187:drug effects*; D003072:Cognition Disorders / Q000178:diet therapy* / Q000523:psychology; D004326:Drinking; D005260:Female; D006801:Humans; D008297:Male; D010865:Pilot Projects; D013662:Tea
chemical_list: D013662:Tea