title: Synthesis and structure of sulfur derivatives from 2-aminobenzimidazole.
abstract: The reactions of the benzimidazole nitrogen atoms and the exocyclic amino group of 2-aminobenzimidazole with CS2 in NaOH basic medium followed by methylation with methyl iodide was explored. With careful control of the stoichiometric quantities and addition sequences, this set of reactions allows the selective functionalization of the benzimidazole ring with N-dithiocarbamate, S-methyldithiocarbamate or dimethyl- dithiocarboimidate groups. The products were characterized by 1H-, 13C-NMR spectroscopy and three of them by X-ray diffraction analysis. The preferred isomers, tautomers and conformers were established.
authors.affiliation: Instituto Politécnico Nacional-UPIBI, Departamento de Ciencias Básicas, Av. Acueducto s/n Barrio la Laguna Ticomán, 07340 México, D.F., Mexico. alcralmx@hotmail.com.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Cruz
authors.affiliation: Instituto Politécnico Nacional-UPIBI, Departamento de Ciencias Básicas, Av. Acueducto s/n Barrio la Laguna Ticomán, 07340 México, D.F., Mexico. ipadillamar@ipn.mx.
authors.forename: Itzia I
authors.initials: II
authors.lastname: Padilla-Martínez
authors.affiliation: Instituto Politécnico Nacional-UPIBI, Departamento de Ciencias Básicas, Av. Acueducto s/n Barrio la Laguna Ticomán, 07340 México, D.F., Mexico. efren1003@yahoo.com.mx.
authors.forename: Efrén V
authors.initials: EV
authors.lastname: García-Báez
authors.affiliation: Instituto Politécnico Nacional-UPIBI, Departamento de Ciencias Básicas, Av. Acueducto s/n Barrio la Laguna Ticomán, 07340 México, D.F., Mexico. ger_2202@hotmail.com.
authors.forename: Gerardo
authors.initials: G
authors.lastname: Guerrero-Muñoz
mesh_terms: D001562:Benzimidazoles / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013455:Sulfur / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D001562:Benzimidazoles; D013455:Sulfur; C027391:2-aminobenzimidazole