title: Bladder capacity in kidney transplant patients with end-stage renal disease.
abstract: BACKGROUND
  This study evaluated the clinical factors that influence bladder capacity and lower urinary tract dysfunction (LUTD) following kidney transplantation (KT) in end-stage renal disease (ESRD) patients.
  
  
  METHODS
  Data were analyzed in ESRD patients who underwent KT between January 2011 and January 2013. The analyzed pre-KT parameters include bladder capacity, vesicoureteral reflux (VUR), postvoid residual urine (PVR), micturition frequency, and voiding volume. Associations between pre-KT parameters, small bladder capacity (<100 cc), and parameters that influence the development of LUTD were also evaluated. LUTD after KT was defined as voiding symptoms that lasted >1 month and required specific treatment.
  
  
  RESULTS
  In total, 622 ESRD patients required KT. The mean age and dialysis duration were 43.9±11.2 years and 59.4±60.7 months. The mean bladder capacity before KT was 300.1±149.8 mL, and 14% of patients were diagnosed with small bladder capacity. VUR and PVR were observed in 110 (17.5%) and 83 (13.6%) patients. Factors associated with small bladder capacity included long-term dialysis, presence of VUR, and PVR (p<0.001, p=0.004, p=0.003). After KT, 31 patients (4.9%) needed treatment due to LUTD. Factors associated with the development of LUTD included age, VUR, and PVR (p=0.001 p=0.034, p<0.001). Bladder capacity did not affect LUTD after KT.
  
  
  CONCLUSIONS
  ESRD patients on long-term dialysis will likely have small bladder capacity and VUR; however, bladder capacity itself is not related to the occurrence of LUTD after KT.
authors.affiliation: Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro, 43-gil, Songpa-gu, Seoul, 138-736, Korea.
authors.forename: Miho
authors.initials: M
authors.lastname: Song
authors.forename: Junsoo
authors.initials: J
authors.lastname: Park
authors.forename: Young Hoon
authors.initials: YH
authors.lastname: Kim
authors.forename: Duck Jong
authors.initials: DJ
authors.lastname: Han
authors.forename: Sang Hoon
authors.initials: SH
authors.lastname: Song
authors.forename: Myung-Soo
authors.initials: MS
authors.lastname: Choo
authors.forename: Bumsik
authors.initials: B
authors.lastname: Hong
mesh_terms: D000328:Adult; D000367:Age Factors; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation / Q000009:adverse effects*; D059411:Lower Urinary Tract Symptoms / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D006435:Renal Dialysis / Q000009:adverse effects*; D013997:Time Factors; D001743:Urinary Bladder / Q000033:anatomy & histology*; D014718:Vesico-Ureteral Reflux / Q000150:complications