title: Monodisperse sphere-on-sphere silica particles for fast HPLC separation of peptides and proteins.
abstract: Monodisperse sphere-on-sphere (SOS) silica particles are produced in a one-pot reaction, removing the need for time-consuming preparation and classification steps. Analysis of peptides and proteins using HPLC displays faster separation at lower operating pressure than commercially available fused core materials.
authors.affiliation: Department of Chemistry, University of Liverpool, Liverpool, L69 7ZD, UK. zhanghf@liv.ac.uk.
authors.forename: Richard
authors.initials: R
authors.lastname: Hayes
authors.forename: Peter
authors.initials: P
authors.lastname: Myers
authors.forename: Tony
authors.initials: T
authors.lastname: Edge
authors.forename: Haifei
authors.initials: H
authors.lastname: Zhang
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D008855:Microscopy, Electron, Scanning; D010455:Peptides / Q000302:isolation & purification*; D011506:Proteins / Q000302:isolation & purification*; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: D010455:Peptides; D011506:Proteins; D012822:Silicon Dioxide