title: Neonatal ascites in autosomal recessive polycystic kidney disease (ARPKD).
abstract: BACKGROUND
  Neonatal ascites is a rare entity, which is usually biliary, urinary, or chylous. Congenital hepatic fibrosis as part of the manifestations of autosomal recessive polycystic kidney disease (ARPKD) is usually a histological adjunct to the diagnosis of this mainly clinically renal entity in the neonatal period. Case-diagnosis: We describe a rare case of severe ascites in a newborn child complicating ARPKD, which was later confirmed by clinical, histological, and genetic studies.
  
  
  CONCLUSIONS
  ARPKD should be considered in differential diagnosis of neonatal ascites.
authors.forename: Galina
authors.initials: G
authors.lastname: Ling
authors.forename: Daniel
authors.initials: D
authors.lastname: Landau
authors.forename: Carsten
authors.initials: C
authors.lastname: Bergmann
authors.forename: Esther
authors.initials: E
authors.lastname: Maor
authors.forename: Baruch
authors.initials: B
authors.lastname: Yerushalmi
mesh_terms: D001201:Ascites / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D001706:Biopsy; D002648:Child; D004252:DNA Mutational Analysis; D003937:Diagnosis, Differential; D005260:Female; D030342:Genetic Diseases, Inborn; D020022:Genetic Predisposition to Disease; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008103:Liver Cirrhosis; D008107:Liver Diseases / Q000150:complications / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D009154:Mutation; D010641:Phenotype; D017044:Polycystic Kidney, Autosomal Recessive / Q000150:complications* / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D011237:Predictive Value of Tests; D011956:Receptors, Cell Surface / Q000235:genetics; D012307:Risk Factors; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: C451750:PKHD1 protein, human; D011956:Receptors, Cell Surface