title: Iodine Deficiency in a Parenteral Nutrition-Dependent Adolescent With Intestinal Pseudo-Obstruction.
abstract: Routine supplementation of iodine in parenteral nutrition (PN) solutions is not current practice in the United States. In this case study, we describe an incidental finding of goiter in a long-term PN-dependent adolescent. With increased iodine screening, we then identified additional patients with undetectable urinary iodine concentrations in our population of children with short bowel receiving long-term PN. We hypothesize that 2 practice changes are possibly reducing iodine provision to long-term PN-dependent patients: transition to alcohol-based skin preparations and lipid minimization.
authors.affiliation: Seattle Children's Hospital, Seattle, Washington mmorte@seattlechildrens.org.
authors.forename: Melissa
authors.initials: M
authors.lastname: Mortensen
authors.affiliation: Seattle Children's Hospital, Seattle, Washington.
authors.forename: Nila
authors.initials: N
authors.lastname: Williamson
authors.affiliation: Seattle Children's Hospital, Seattle, Washington.
authors.forename: Cheryl
authors.initials: C
authors.lastname: Davis
authors.affiliation: Division of Gastroenterology and Hepatology, Seattle Children's Hospital, Seattle, Washington University of Washington School of Medicine, Seattle.
authors.forename: Evelyn
authors.initials: E
authors.lastname: Kanyu Hsu
authors.affiliation: Division of Pediatric General and Thoracic Surgery, Seattle Children's Hospital, Seattle, Washington Department of Surgery, University of Washington School of Medicine, Seattle.
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Javid
authors.affiliation: University of Washington School of Medicine, Seattle Liver and Intestinal Transplantation, Seattle Children's Hospital, Seattle, Washington.
authors.forename: Simon
authors.initials: S
authors.lastname: Horslen
mesh_terms: D000293:Adolescent; D019587:Dietary Supplements; D006042:Goiter / Q000150:complications / Q000175:diagnosis; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000150:complications / Q000628:therapy*; D007455:Iodine / Q000008:administration & dosage / Q000172:deficiency* / Q000652:urine; D008297:Male; D010288:Parenteral Nutrition; D013974:Thyroxine / Q000627:therapeutic use
chemical_list: D007455:Iodine; D013974:Thyroxine
keywords: life cycle; minerals/trace elements; nutrition; parenteral nutrition; pediatrics