title: Primary burkitt lymphoma of the fourth ventricle in an immunocompetent young patient.
abstract: Primary Burkitt lymphoma of the central nervous system (CNS) is rare, with only few cases reported in the literature. An 18 year-old immunocompetent male presented with multiple cranial nerves palsies and was found to have a mass predominantly in the 4th ventricle of the brain. Tumor was surgically removed and showed morphological and immunohistochemical features consistent with Burkitt lymphoma. The patient responded very well to anthracycline based chemotherapy with high dose methotrexate (HD MTX) and intrathecal (IT) chemotherapy delivered by Ommaya reservoir. Primary Burkitt lymphoma of the CNS is a rare entity that poses differential diagnostic challenge with other small round blue cell tumors.
authors.affiliation: Department of Pathology, King Abdulaziz Medical City, Riyadh 14611, Saudi Arabia.
authors.forename: Abdulrahman
authors.initials: A
authors.lastname: Alabdulsalam
authors.affiliation: Department of Adult Hematology/BMT, CCC, King Fahad Medical City, Riyadh 11525, Saudi Arabia.
authors.forename: Syed Z A
authors.initials: SZ
authors.lastname: Zaidi
authors.affiliation: Department of Adult Hematology/BMT, CCC, King Fahad Medical City, Riyadh 11525, Saudi Arabia.
authors.forename: Imran
authors.identifier: 0000-0002-7212-2811
authors.initials: I
authors.lastname: Tailor
authors.affiliation: Department of Adult Neurosurgery, NNI, King Fahad Medical City, Riyadh 11525, Saudi Arabia.
authors.forename: Yasser
authors.initials: Y
authors.lastname: Orz
authors.affiliation: Department of Pathology, King Fahad Medical City, Riyadh 11525, Saudi Arabia.
authors.forename: Sadeq
authors.identifier: 0000-0003-3373-7327
authors.initials: S
authors.lastname: Al-Dandan