title: Differentiation of noncalculous periampullary obstruction: comparison of CT with negative-contrast CT cholangiopancreatography versus MRI with MR cholangiopancreatography.
abstract: OBJECTIVE
  The purpose of this study was to compare CT with negative-contrast CT cholangiopancreatography (nCTCP) using subvolume minimum intensity projection (MinIP) versus MRI with MRCP in differentiating noncalculous periampullary obstruction.
  
  
  METHODS
  Sixty-four patients with clinically proven noncalculous periampullary obstructions who had undergone both MDCT and MR examinations before operation were reviewed retrospectively. Two reviewers independently interpreted the two image sets (the CT with nCTCP set [CT set] vs. the MRI with MRCP set [MRI set]) in differentiating both benign from malignant obstruction and pancreatic head carcinoma (PHC) from non-PHC, and the results were compared to the final clinical records.
  
  
  RESULTS
  In this study, no statistically significant differences were observed in the accuracy of differentiating benign from malignant periampullary obstruction (p = 0.754 for reviewer 1 and p = 0.508 for reviewer 2) on the two image sets. The accuracy of differentiating PHC from non-PHC was also statistically insignificant (p = 0.125 for reviewer 1 and p = 1.000 for reviewer 2) on the two image sets.
  
  
  CONCLUSIONS
  The CT set provides a comparable performance to that of the MRI set in differentiating noncalculous periampullary obstruction.
  
  
  CONCLUSIONS
  • nCTCP with subvolume MinIP is a practical tool in evaluating biliary obstruction • Two image sets have a comparable performance in differentiating noncalculous periampullary obstruction • MDCT could serve as an alternative in patients not eligible for MRI.
authors.affiliation: Department of Radiology, Wuxi Second People's Hospital Affiliated to Nanjing Medical University, Zhongshan Road 68, Wuxi, Jiangsu Province, 214002, People's Republic of China.
authors.forename: Bin
authors.initials: B
authors.lastname: Li
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.forename: Zhui-Yang
authors.initials: ZY
authors.lastname: Zhang
authors.forename: Jian-Ming
authors.initials: JM
authors.lastname: Ni
authors.forename: Feng-qi
authors.initials: FQ
authors.lastname: Lu
authors.forename: Wen-Juan
authors.initials: WJ
authors.lastname: Wu
authors.forename: Chun-juan
authors.initials: CJ
authors.lastname: Jiang
mesh_terms: D000328:Adult; D000368:Aged; D049448:Cholangiopancreatography, Magnetic Resonance / Q000379:methods*; D002779:Cholestasis / Q000175:diagnosis* / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography / Q000379:methods*; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000175:diagnosis; D012372:ROC Curve; D015203:Reproducibility of Results; D012189:Retrospective Studies