title: Vaginal delivery after hemipelvectomy and pelvic radiotherapy for chondrosarcoma.
abstract: Chondosarcoma of the proximal femur is a rare malignant disorder in women of (pre-) childbearing age, for which a radical resection through a hemipelvectomy could be indicated. We describe a case of a 36-year-old primigravida with a hemipelvectomy (2004) who had a history of radiotherapy of the pelvic and uterine regions after an atypical cartilaginous tumour. After an uncomplicated pregnancy, she had a spontaneous rupture of the membranes at 41+2 weeks and an uncomplicated vaginal delivery with physiological development of the infant. On the basis of the literature review, vaginal delivery after hemipelvectomy should be advocated and discussed with the patient and involved care providers. Women with radiotherapy in the pelvic and uterine areas have an increased risk of stillbirth, placental attachment disorders, impaired fetal growth, fetal malposition and preterm labour, but no association with prolonged rupture of the membranes has been described.
authors.affiliation: Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands.
authors.forename: J L
authors.initials: JL
authors.lastname: Browne
authors.affiliation: Division of Woman and Baby, Department of Obstetrics and Gynaecology, University Medical Centre Utrecht, Utrecht, The Netherlands.
authors.forename: M A
authors.initials: MA
authors.lastname: Oudijk
authors.affiliation: Department of Rehabilitation, Nursing Science and Sport, University Medical Centre Utrecht, Utrecht, The Netherlands Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht, The Netherlands.
authors.forename: H R
authors.initials: HR
authors.lastname: Holtslag
authors.affiliation: Division of Woman and Baby, Department of Obstetrics and Gynaecology, University Medical Centre Utrecht, Utrecht, The Netherlands.
authors.forename: H W R
authors.initials: HW
authors.lastname: Schreuder
mesh_terms: D000328:Adult; D002813:Chondrosarcoma / Q000628:therapy*; D036861:Delivery, Obstetric / Q000379:methods*; D005260:Female; D005266:Femoral Neoplasms / Q000628:therapy*; D006428:Hemipelvectomy; D006801:Humans; D010388:Pelvis; D011247:Pregnancy; D011878:Radiotherapy