title: [Analysis of the medicinal leech effects on the state of arterial functions of aged probationers, using hardwarily software system "Angioscan-01"].
abstract: The state of elderly patients arterial wall after the putting of one medicinal leech was estimated by use hardwarily software system "Angioscan-01". There was compared the effect of one medicinal leech on indicators of vasomotor function of endothelium of small resistance arteries and of middle arteries of muscular type. Stickiness index and augmentation index were determined in order to evaluate the medicinal leech effect on the rigidity state of arterial wall. It is shown that the putting of one leech stimulates the improving of endothelium vasomotor function and of normalization arterial wall stickiness. It is supposed the participation in this process the secretion of the medicinal leech salivary cells, which, as has been shown recently, is able to activate e-NOS and n-NOS in human endothelium culture (HUVEC) and increase NO level. Elevation of share stress during occlusion test is also stimulated NO production in vascular endothelium.
authors.forename: I P
authors.initials: IP
authors.lastname: Baskova
authors.forename: I B
authors.initials: IB
authors.lastname: Pavlova
authors.forename: A S
authors.initials: AS
authors.lastname: Parfenov
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D001158:Arteries / Q000503:physiopathology*; D001815:Bloodletting / Q000379:methods; D005260:Female; D024764:Hirudin Therapy / Q000379:methods*; D047709:Hirudo medicinalis; D006801:Humans; D008297:Male; D008875:Middle Aged