title: [Transdisciplinary Approach for Sarcopenia. Effect of nutritional support for the prevention of sarcopenia].
abstract: Sarcopenia is defined as the age-related loss of muscle mass and function. Sarcopenia is closely related with decreased physical function, fall, bone fracture, osteoporosis, and insulin resistance, which lead to increased morbidity and mortality in elderly people. The pathogenesis of sarcopenia is complex and multifactorial, which remains not to be fully understood. Inappropriate food intake and reduced physical activity are known to increase the risk of developing sarcopenia. Resistance training and nutritional support have been shown to be an effective intervention for prevention of sarcopenia. Protein, especially branched chain amino acid, and vitamin D have been reported to improve sarcopenia. The intervention together with nutrition and exercise are more effective.
authors.affiliation: Department of General Internal Medicine, Kobe City Medical Center General Hospital, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Nishioka
mesh_terms: D000596:Amino Acids / Q000008:administration & dosage / Q000378:metabolism; D015444:Exercise; D006801:Humans; D018482:Muscle, Skeletal / Q000378:metabolism; D009752:Nutritional Status; D055948:Sarcopenia / Q000517:prevention & control* / Q000628:therapy; D014807:Vitamin D / Q000008:administration & dosage / Q000378:metabolism
chemical_list: D000596:Amino Acids; D014807:Vitamin D