title: How the immune system spots tumors.
abstract: The receptor protein Dectin-1 recognizes structures found on cancerous cells, and then triggers an anti-tumor immune response.
authors.affiliation: Yasutaka Okabe is in the Department of Immunobiology, Yale University School of Medicine, New Haven, United States.
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Okabe
authors.affiliation: Ruslan Medzhitov is an eLife reviewing editor, and is in the Department of Immunobiology, Yale University School of Medicine, New Haven, United States ruslan.medzhitov@yale.edu.
authors.forename: Ruslan
authors.initials: R
authors.lastname: Medzhitov
mesh_terms: D000818:Animals; D006801:Humans; D007113:Immunity, Innate / Q000276:immunology*; D037181:Lectins, C-Type / Q000378:metabolism*; D008546:Melanoma, Experimental / Q000276:immunology* / Q000473:pathology*; D000099181:Dectin-1
chemical_list: D037181:Lectins, C-Type; D000099181:Dectin-1
keywords: Dectin-1; IRF; NK cell; cancer; immunology; innate immunity; mouse