title: Strabismus resulting from an anomalous extraocular muscle in Gorlin syndrome.
abstract: Strabismus associated with anomalous extraocular muscles is rare. We present a case of strabismus caused by an anomalous orbital structure that was histopathologically consistent with an accessory extraocular muscle rather than a fibrous band, in a patient with Gorlin syndrome (nevoid basal cell carcinoma syndrome), an autosomal dominant multisystem disorder related to a mutation in the patched tumor suppressor gene (PTCH). Histopathology of an anomalous orbital structure consistent with extraocular muscle has not been previously reported.
authors.affiliation: University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
authors.forename: Peter B
authors.initials: PB
authors.lastname: Knowlton
authors.affiliation: Vanderbilt Eye Institute, Vanderbilt University School of Medicine, Nashville, Tennessee.
authors.forename: Louise A
authors.initials: LA
authors.lastname: Mawn
authors.affiliation: Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee.
authors.forename: James B
authors.initials: JB
authors.lastname: Atkinson
authors.affiliation: Vanderbilt Eye Institute, Vanderbilt University School of Medicine, Nashville, Tennessee. Electronic address: sean.donahue@vanderbilt.edu.
authors.forename: Sean P
authors.initials: SP
authors.lastname: Donahue
mesh_terms: D001478:Basal Cell Nevus Syndrome / Q000150:complications*; D005124:Eye Abnormalities / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D007223:Infant; D008297:Male; D009801:Oculomotor Muscles / Q000002:abnormalities* / Q000000981:diagnostic imaging; D007690:Polycystic Kidney Diseases / Q000150:complications; D013285:Strabismus / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D014057:Tomography, X-Ray Computed