title: [Current issues in functional dyspepsia].
abstract: Functional dyspepsia is one of the most common gastrointestinal disorders encountered in clinical practice. Functional dyspepsia is currently defined by Rome III criteria as the chronic dyspeptic symptoms (postprandial fullness, early satiety, epigastric pain or burning) in the absence of underling structural or metabolic disease that readily explain the symptoms. According to the Rome III consensus, functional dyspepsia can be subdivided into postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS). Although the Rome III criteria have been published more than 8 years ago, not much effort has been put into validating these criteria and direct scientific evidence supporting the validity of the subdividing functional dyspepsia into PDS and EPS are lacking. This article is intended to review the validity of the Rome III criteria on the subdivisions of functional dyspepsia, i.e. PDS and EPS. The impact of sleep disorder, Helicobacter pylori-associated dyspepsia, and the emerging drug therapies in functional dyspepsia will also be discussed in this article.
authors.affiliation: Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Jong Kyu
authors.initials: JK
authors.lastname: Park
authors.affiliation: Konyang University College of Medicine, Daejeon, Korea.
authors.forename: Kyu Chan
authors.initials: KC
authors.lastname: Huh
authors.affiliation: Seoul National University College of Medicine, Seongnam, Korea.
authors.forename: Cheol Min
authors.initials: CM
authors.lastname: Shin
authors.affiliation: Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Hyuk
authors.initials: H
authors.lastname: Lee
authors.affiliation: Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Young Hoon
authors.initials: YH
authors.lastname: Yoon
authors.affiliation: Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Kyung Ho
authors.initials: KH
authors.lastname: Song
authors.affiliation: Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Byung Hoon
authors.initials: BH
authors.lastname: Min
authors.affiliation: Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Kee Don
authors.initials: KD
authors.lastname: Choi
mesh_terms: D014151:Anti-Anxiety Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004415:Dyspepsia / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D005765:Gastrointestinal Agents / Q000627:therapeutic use; D016481:Helicobacter Infections / Q000150:complications / Q000175:diagnosis; D006801:Humans; D017366:Serotonin Receptor Agonists / Q000627:therapeutic use; D012720:Severity of Illness Index; D012893:Sleep Wake Disorders / Q000209:etiology
chemical_list: D014151:Anti-Anxiety Agents; D005765:Gastrointestinal Agents; D017366:Serotonin Receptor Agonists
keywords: Diagnosis; Functional dyspepsia; Helicobacter pylori; Sleep disorder