title: Umbilical artery blood flows among pregnancies with single umbilical artery: a prospective case-control study.
abstract: OBJECTIVE
  To evaluate peak systolic velocity (PSV) in the umbilical artery (UA) among patients with single umbilical artery (SUA) as compared with patients with three vessel cords.
  
  
  METHODS
  A prospective case-control study was performed. UA blood flow velocimetry was obtained from fetuses with SUA and from a control group with three vessel cord. PSV and pulsatility index (PI) were measured. Patients' characteristics were compared for statistical differences and a linear regression model was constructed for the different groups.
  
  
  RESULTS
  UA Doppler velocimetry measurements were obtained from 29 patients with SUA and from 29 controls matched for gestational age. The differences between UA PI with and without SUA were significant (F = 3.471; p = 0.0379) showing a lower PI in the SUA group. However, no significant statistical difference was found in PSV between these two groups (F = 0.149; p = 0.86).
  
  
  CONCLUSIONS
  While the impedance in the UA of patients with a SUA was lower compared with patients with a normal umbilical cord, the PSV did not differ.
authors.affiliation: a Department of Obstetrics and Gynecology , Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev , Israel and.
authors.forename: Joel
authors.initials: J
authors.lastname: Baron
authors.forename: Adi Y
authors.initials: AY
authors.lastname: Weintraub
authors.forename: Yael
authors.initials: Y
authors.lastname: Sciaky
authors.forename: Salvatore A
authors.initials: SA
authors.lastname: Mastrolia
authors.forename: Efrat
authors.initials: E
authors.lastname: Speigel
authors.forename: Reli
authors.initials: R
authors.lastname: Hershkovitz
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity; D016022:Case-Control Studies; D005260:Female; D020567:Fetal Weight; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D058529:Single Umbilical Artery / Q000503:physiopathology*; D018608:Ultrasonography, Doppler; D016216:Ultrasonography, Prenatal; D014469:Umbilical Arteries / Q000502:physiology / Q000503:physiopathology; D055815:Young Adult
keywords: Doppler flow velocimetry; peak systolic velocity; pulsatility index; single umbilical artery