title: Protocadherins: not just neuron glue, more too!
abstract: Selective fasciculation, in which axons navigate toward their targets along preexisting "pioneer" axons, requires specific cell-cell contacts to ensure proper target innervation. In this issue of Developmental Cell, Hayashi et al. (2014) show that the adhesion molecule Protocadherin-17 regulates selective fasciculation by promoting growth, rather than adhesion, of amygdala axons.
authors.affiliation: Institute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland. Electronic address: esther.stoeckli@imls.uzh.ch.
authors.forename: Esther T
authors.initials: ET
authors.lastname: Stoeckli
mesh_terms: D000199:Actins / Q000378:metabolism*; D000818:Animals; D001369:Axons / Q000378:metabolism*; D015820:Cadherins / Q000378:metabolism*; D020439:Growth Cones / Q000378:metabolism*; D000091363:Protocadherins
chemical_list: D000199:Actins; D015820:Cadherins; C504473:Pcdh1 protein, mouse; D000091363:Protocadherins