title: Computer-assisted cognitive behavioral therapy for pregnant women with major depressive disorder.
abstract: BACKGROUND
  Pregnant women with major depressive disorder (MDD) report that psychotherapy is a more acceptable treatment than pharmacotherapy. However, although results of several studies suggest that psychotherapy is an effective treatment for pregnant women, logistical barriers-including cost and traveling for weekly visits-can limit real-world utility. We hypothesized that computer-assisted cognitive behavior therapy (CCBT) would be both acceptable and would significantly decrease depressive symptoms in pregnant women with MDD.
  
  
  METHODS
  As a preliminary test of this hypothesis, we treated 10 pregnant women with MDD using a standardized CCBT protocol.
  
  
  RESULTS
  The pilot results were very promising, with 80% of participants showing treatment response and 60% showing remission after only eight sessions of CCBT.
  
  
  CONCLUSIONS
  A larger, randomized controlled trial of CCBT in pregnant women with MDD is warranted.
authors.affiliation: 1 Penn Center for Women's Behavioral Wellness, Perelman School of Medicine at the University of Pennsylvania , Philadelphia, Pennsylvania.
authors.forename: Deborah R
authors.initials: DR
authors.lastname: Kim
authors.forename: Liisa
authors.initials: L
authors.lastname: Hantsoo
authors.forename: Michael E
authors.initials: ME
authors.lastname: Thase
authors.forename: Mary
authors.initials: M
authors.lastname: Sammel
authors.forename: C Neill
authors.initials: CN
authors.lastname: Epperson
mesh_terms: D000293:Adolescent; D000328:Adult; D015928:Cognitive Behavioral Therapy / Q000191:economics / Q000379:methods*; D003362:Cost-Benefit Analysis; D003865:Major Depressive Disorder / Q000523:psychology / Q000628:therapy*; D005240:Feasibility Studies; D005260:Female; D006297:Health Services Accessibility; D006801:Humans; D008875:Middle Aged; D010342:Patient Acceptance of Health Care / Q000706:statistics & numerical data*; D017060:Patient Satisfaction; D010865:Pilot Projects; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D012959:Socioeconomic Factors; D013813:Therapy, Computer-Assisted / Q000191:economics / Q000379:methods*; D016896:Treatment Outcome; D055815:Young Adult