title: Treatment response to the RENEW weight loss intervention in schizophrenia: impact of intervention setting.
abstract: BACKGROUND
  Individuals with serious mental illness have high rates of obesity and a need for specialized weight loss intervention programs. This study examines the efficacy of the RENEW weight loss intervention and examines the impact of the intervention setting on outcomes.
  
  
  METHODS
  136 individuals with serious mental illness from 4 different settings were randomly assigned to receive the RENEW weight loss intervention or a control condition of treatment as usual. The RENEW intervention is a one year program that includes an intensive, maintenance and intermittent supports phase.
  
  
  RESULTS
  The intervention group experienced a modest weight loss of 4.8 lbs at 3 months, 4.1 lbs at 6 months and a slight weight gain of 1.5 lbs at 12 months. The control group gained a total of 6.2 lbs at 12 months. However when settings were examined separately the responder sites had a weight loss of 9.4 lbs at 3 months, 10.9 lbs at 6 months and 7 lbs at 12 months.
  
  
  CONCLUSIONS
  These results suggest that the settings in which individuals receive services may act as a support or hindrance toward response to weight loss interventions. The concept of the obesogenic environment deserves further examination as a factor in the success of weight loss programs.
authors.affiliation: Midwestern University, College of Health Sciences, Glendale, United States. Electronic address: cbrown2@midwestern.edu.
authors.forename: Catana
authors.initials: C
authors.lastname: Brown
authors.affiliation: University of Kansas, School of Allied Health, United States.
authors.forename: Jeannine
authors.initials: J
authors.lastname: Goetz
authors.affiliation: University of Kansas, School of Nursing, United States.
authors.forename: Edna
authors.initials: E
authors.lastname: Hamera
authors.affiliation: University of Kansas, School of Allied Health, United States.
authors.forename: Byron
authors.initials: B
authors.lastname: Gajewski
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000139:chemically induced / Q000517:prevention & control*; D012559:Schizophrenia / Q000188:drug therapy / Q000534:rehabilitation*; D016896:Treatment Outcome; D015431:Weight Loss / Q000502:physiology*; D061217:Weight Reduction Programs / Q000592:standards*
chemical_list: D014150:Antipsychotic Agents
keywords: Intervention; Obesity; Schizophrenia; Weight loss