title: Is physical activity a protective factor against pancreatic cancer?
abstract: OBJECTIVE
  The objective of the study was to analyze an association between selected factors and pancreatic cancer, assuming that knowing the etiology would help influence the incidence of this severe type of cancer through primary prevention. In addition to age, gender, BMI and education, the analysis aimed at assessing occupational and leisure-time physical activities with respect to pancreatic cancer.
  
  
  BACKGROUND
  In numerous studies, physical activity is reported to be a protective factor against pancreatic cancer.
  
  
  METHODS
  A case-control study was carried out in three centers in the Czech Republic in 2006-2009.
  
  
  RESULTS
  The study comprised a total of 529 individuals, of which 309 were patients with pancreatic cancer and 220 were controls. Leisure-time physical activity showed a statistically significant inverse association with a crude odds ratio of 0.65 (95% CI 0.45-0.93), even after adjustment for other studied factors (OR =0.63, 95% CI 0.43-0.92). Conversely, for occupational physical activity, a positive association was only suggested.
  
  
  CONCLUSIONS
  Leisure-time physical activity is a protective factor against the development of pancreatic cancer. Occupational physical activity was not confirmed as a protective factor against pancreatic cancer (Tab. 4, Fig. 1, Ref. 22).
authors.forename: H
authors.initials: H
authors.lastname: Kollarova
authors.forename: K
authors.initials: K
authors.lastname: Azeem
authors.forename: H
authors.initials: H
authors.lastname: Tomaskova
authors.forename: D
authors.initials: D
authors.lastname: Horakova
authors.forename: V
authors.initials: V
authors.lastname: Prochazka
authors.forename: A
authors.initials: A
authors.lastname: Martinek
authors.forename: O
authors.initials: O
authors.lastname: Shonova
authors.forename: J
authors.initials: J
authors.lastname: Sevcikova
authors.forename: V
authors.initials: V
authors.lastname: Sevcikova
authors.forename: V
authors.initials: V
authors.lastname: Janout
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D016022:Case-Control Studies; D015444:Exercise; D005260:Female; D006801:Humans; D007899:Leisure Activities; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D010190:Pancreatic Neoplasms / Q000453:epidemiology* / Q000517:prevention & control; D012737:Sex Factors; D012959:Socioeconomic Factors