title: Heteroclitins R-S: new dibenzocylooctadiene lignans from Kadsura heteroclita.
abstract: OBJECTIVE
  To study the dibenzocylooctadiene lignans from the stems of Kadsura heteroclita.
  
  
  METHODS
  Chromatographic separations of silica gel and semi-preparative HPLC were used. All of the structures were elucidated on the basis of spectroscopic analysis, including 2D-NMR and HR-MS techniques.
  
  
  RESULTS
  Four dibenzocylooctadiene lignans were isolated from K. heteroclita. Their structures were identified as heteroclitin R (1), heteroclitin S (2), gonisin O (3), and schisanlignone A (4).
  
  
  CONCLUSIONS
  Heteroclitin R (1) and heteroclitin S (2) are new natural lignans.
authors.affiliation: Key Laboratory on Luminescence and Real-Time Analysis (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China. Electronic address: mminchen@swu.edu.cn.
authors.forename: Min
authors.initials: M
authors.lastname: Chen
authors.affiliation: Key Laboratory on Luminescence and Real-Time Analysis (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China; College of Chemistry and Chemical Engineering, HaiNan Normal University, Hai Kou 571158, China.
authors.forename: You-Ping
authors.initials: YP
authors.lastname: Luo
authors.affiliation: Key Laboratory on Luminescence and Real-Time Analysis (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China.
authors.forename: Yan-Lin
authors.initials: YL
authors.lastname: Zou
authors.affiliation: Key Laboratory on Luminescence and Real-Time Analysis (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China.
authors.forename: Ling-Hu
authors.initials: LH
authors.lastname: Lang
authors.affiliation: Department of Pharmacognosy, School of Pharmacy, Fudan University, Shanghai 201203, China.
authors.forename: Dao-Feng
authors.initials: DF
authors.lastname: Chen
mesh_terms: D032135:Kadsura / Q000737:chemistry*; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*
chemical_list: D017705:Lignans; D010936:Plant Extracts
keywords: Dibenzocylooctadiene Lignan; Heteroclitins R-S; Kadsura heteroclita; Schisandraceae