title: [Comparison of the occlusion effect of three kinds of desensitizers on dentinal tubules].
abstract: OBJECTIVE
  To explore the effects of three dentine desensitizers on the surface morphology of freshly exposed dentin and to evaluate their occlusion effects on dentinal tubules using scanning electron microscope (SEM).
  
  
  METHODS
  A total of 16 isolated human premolar samples, which were prepared to expose dentine, were randomly divided into a control group (n=4), a Hybrid Coat group (n=4), a Prime & Bond NT group (n=4), and a anti-sensitivity toothpaste group (n=4). After treatment with dentine desensitizers, one half of the samples in each group were vertically cleaved. Finally, the surfaces and cross sections of the samples were observed by SEM.
  
  
  RESULTS
  The exposed tubule was almost occluded in the Hybrid Coat group and the Prime & Bond NT group, while only the majority of tubules could be sealed in the anti-sensitivity toothpaste group. The cross-section images showed that sediments were visible in all groups except the control group.
  
  
  CONCLUSIONS
  Hybrid Coat and Prime & Bond NT are able to effectively seal tubules, while the effect of anti-sensitivity toothpaste is slightly poor.
authors.affiliation: Stomatology Centre, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Chen
authors.forename: Fei
authors.initials: F
authors.lastname: Xu
authors.forename: Zhenjie
authors.initials: Z
authors.lastname: Guan
authors.forename: Weidan
authors.initials: W
authors.lastname: Zhang
authors.forename: Xiaojuan
authors.initials: X
authors.lastname: Wang
mesh_terms: D003804:Dentin / Q000648:ultrastructure*; D057133:Dentin Desensitizing Agents / Q000494:pharmacology*; D003806:Dentin Permeability / Q000187:drug effects*; D006801:Humans; D008855:Microscopy, Electron, Scanning; D011109:Polymethacrylic Acids / Q000494:pharmacology; D014100:Toothpastes / Q000494:pharmacology*
chemical_list: D057133:Dentin Desensitizing Agents; D011109:Polymethacrylic Acids; C425843:Prime and Bond NT; D014100:Toothpastes