title: Comprehensive analysis of DNA methylation data with RnBeads.
abstract: RnBeads is a software tool for large-scale analysis and interpretation of DNA methylation data, providing a user-friendly analysis workflow that yields detailed hypertext reports (http://rnbeads.mpi-inf.mpg.de/). Supported assays include whole-genome bisulfite sequencing, reduced representation bisulfite sequencing, Infinium microarrays and any other protocol that produces high-resolution DNA methylation data. Notable applications of RnBeads include the analysis of epigenome-wide association studies and epigenetic biomarker discovery in cancer cohorts.
authors.affiliation: Max Planck Institute for Informatics, Saarbrücken, Germany.
authors.forename: Yassen
authors.initials: Y
authors.lastname: Assenov
authors.affiliation: Max Planck Institute for Informatics, Saarbrücken, Germany.
authors.forename: Fabian
authors.initials: F
authors.lastname: Müller
authors.affiliation: Department of Genetics/Epigenetics, Saarland University, Saarbrücken, Germany.
authors.forename: Pavlo
authors.initials: P
authors.lastname: Lutsik
authors.affiliation: Department of Genetics/Epigenetics, Saarland University, Saarbrücken, Germany.
authors.forename: Jörn
authors.initials: J
authors.lastname: Walter
authors.affiliation: Max Planck Institute for Informatics, Saarbrücken, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Lengauer
authors.affiliation: Max Planck Institute for Informatics, Saarbrücken, Germany.|CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.|Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
authors.forename: Christoph
authors.initials: C
authors.lastname: Bock
mesh_terms: D001483:Base Sequence; D004247:DNA / Q000737:chemistry*; D019175:DNA Methylation; D044127:Epigenesis, Genetic; D015894:Genome, Human; D006801:Humans; D017422:Sequence Analysis, DNA / Q000379:methods; D012984:Software; D013447:Sulfites / Q000737:chemistry
chemical_list: D013447:Sulfites; D004247:DNA; C042345:hydrogen sulfite