title: In vitro free radical scavenging activity of ethanolic extract of the whole plant of Evolvulus alsinoides (L.) L.
abstract: OBJECTIVE
  To identify the free radical scavenging activity of ethanolic extract of Evolvulus alsinoides.
  
  
  METHODS
  The free radical scavenging activity was evaluated by in vitro methods like reducing power assay, total antioxidant activity, 2,2-diphenyl-1-picrylhydrazyl (DPPH) reduction, superoxide radical scavenging activity, 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS(+)) scavenging activity, hydroxyl radical scavenging assay, and nitric oxide radical scavenging assay, which were studied by using ascorbic acid as standard.
  
  
  RESULTS
  The extract showed significant activities in all antioxidant assays compared with the reference antioxidant ascorbic acid. The total antioxidant activity as well as the reducing power was also found to increase in a dose-dependent manner.
  
  
  CONCLUSIONS
  Evolvulus alsinoides may act as a chemopreventive agent, providing antioxidant properties and offering effective protection from free radicals.
authors.affiliation: Department of Biochemistry, Karpagam University, Coimbatore, 641021, India.
authors.forename: Duraisamy
authors.initials: D
authors.lastname: Gomathi
authors.forename: Ganesan
authors.initials: G
authors.lastname: Ravikumar
authors.forename: Manokaran
authors.initials: M
authors.lastname: Kalaiselvi
authors.forename: Balasubramaniam
authors.initials: B
authors.lastname: Vidya
authors.forename: Chandrasekar
authors.initials: C
authors.lastname: Uma
mesh_terms: D000975:Antioxidants / Q000737:chemistry; D052160:Benzothiazoles / Q000737:chemistry; D001713:Biphenyl Compounds / Q000737:chemistry; D027722:Convolvulaceae / Q000737:chemistry*; D000431:Ethanol / Q000737:chemistry*; D016166:Free Radical Scavengers / Q000737:chemistry*; D017665:Hydroxyl Radical / Q000737:chemistry; D009569:Nitric Oxide / Q000737:chemistry; D010084:Oxidation-Reduction / Q000187:drug effects; D010851:Picrates / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry*; D013451:Sulfonic Acids / Q000737:chemistry; D013481:Superoxides / Q000737:chemistry
chemical_list: D000975:Antioxidants; D052160:Benzothiazoles; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D010851:Picrates; D010936:Plant Extracts; D013451:Sulfonic Acids; D013481:Superoxides; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; D009569:Nitric Oxide; D017665:Hydroxyl Radical; D000431:Ethanol; C004931:1,1-diphenyl-2-picrylhydrazyl