title: Energetically demanding transport in a supramolecular assembly.
abstract: A challenge in contemporary chemistry is the realization of artificial molecular machines that can perform work in solution on their environments. Here, we report on the design and production of a supramolecular flashing energy ratchet capable of processing chemical fuel generated by redox changes to drive a ring in one direction relative to a dumbbell toward an energetically uphill state. The kinetics of the reaction pathway juxtapose a low energy [2]pseudorotaxane that forms under equilibrium conditions with a high energy, metastable [2]pseudorotaxane which resides away from equilibrium.
authors.affiliation: Department of Chemistry, Northwestern University , Evanston, Illinois 60208, United States.
authors.forename: Chuyang
authors.initials: C
authors.lastname: Cheng
authors.forename: Paul R
authors.initials: PR
authors.lastname: McGonigal
authors.forename: Wei-Guang
authors.initials: WG
authors.lastname: Liu
authors.forename: Hao
authors.initials: H
authors.lastname: Li
authors.forename: Nicolaas A
authors.initials: NA
authors.lastname: Vermeulen
authors.forename: Chenfeng
authors.initials: C
authors.lastname: Ke
authors.forename: Marco
authors.initials: M
authors.lastname: Frasconi
authors.forename: Charlotte L
authors.initials: CL
authors.lastname: Stern
authors.forename: William A
authors.initials: WA
authors.lastname: Goddard
authors.forename: J Fraser
authors.initials: JF
authors.lastname: Stoddart
mesh_terms: D008958:Models, Molecular; D008968:Molecular Conformation; D010084:Oxidation-Reduction; D011726:Pyridinium Compounds / Q000737:chemistry; D043862:Rotaxanes / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D011726:Pyridinium Compounds; D043862:Rotaxanes