title: Effects of vitamin C and exercise on lipid profile, platelet and erythrocyte indices in young soccer players.
abstract: OBJECTIVE
  Exercise may increase production of reactive oxygen species (ROS) enhancing oxidative stress. Antioxidants can efficiently scavenge ROS before they initiate oxidative damage of biomolecules such as enzymes, nucleic acids, lipids and lipoproteins in the body. Vitamin C, an important antioxidant, may affect oxidative stress in living organism. Therefore, this study was carried out to investigate the effects of exercise and vitamin C on thiobarbituric acid-reactive substance (TBARS), lipid profile, erythrocyte and platelet indices in young soccer players.
  
  
  METHODS
  This investigation was carried out on twenty two male volunteer players in three groups. The first group was examined as a control. The second group was only exposed to exercise. The third group was exposed to exercise plus vitamin C (500 mg/day) administered per oral. The players were 23.50±0.59 year-old, 67.66±1.52 kg body weight and 1.74±0.03 m height. Blood samples were collected in vacutainer tubes for analysis of biochemical and hematological parameters.
  
  
  RESULTS
  While the levels of high density lipoprotein-cholesterol (HDL-C) were significantly increased (P<0.05) with only exercise, the cholesterol and low density lipoprotein-cholesterol (LDL-C) were decreased (P<0.05 to P<0.01) with exercise and exercise plus vitamin C treatment. While TBARS levels were increased (P<0.05) with exercise training, it was decreased (P<0.05) with exercise plus vitamin C treatment. The platelet counts (PLT), mean platelet volume (MPV), plateletcrit (PCT) and red blood cell distribution width (RDW) were significantly decreased (P<0.05) with exercise plus vitamin C. There were significantly correlations (P<0.05 to P<0.01) between lipid values and erythrocyte and platelet indices.
  
  
  CONCLUSIONS
  In light of these results, exercise may play a role in decreasing of LDL-C and in increasing of HDL-C. In addition, exercise plus vitamin C may diminish TBARS-levels and may affect the values of PLT, MPV, PCT and RDW in young soccer players.
authors.affiliation: Department of Physiology, Faculty of Medicine Harran University, Sanliurfa, Turkey - azkar@harran.edu.tr.
authors.forename: A Z
authors.initials: AZ
authors.lastname: Karakilcik
authors.forename: R
authors.initials: R
authors.lastname: Halat
authors.forename: M
authors.initials: M
authors.lastname: Zerin
authors.forename: H
authors.initials: H
authors.lastname: Celik
authors.forename: Y
authors.initials: Y
authors.lastname: Nazligul
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000008:administration & dosage* / Q000378:metabolism; D001205:Ascorbic Acid / Q000008:administration & dosage* / Q000097:blood; D001792:Blood Platelets / Q000378:metabolism*; D004909:Erythrocyte Indices; D015444:Exercise / Q000502:physiology*; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D012916:Soccer / Q000502:physiology*; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism; D014815:Vitamins / Q000008:administration & dosage* / Q000097:blood; D055815:Young Adult
chemical_list: D000975:Antioxidants; D008055:Lipids; D017392:Thiobarbituric Acid Reactive Substances; D014815:Vitamins; D001205:Ascorbic Acid