title: WNT signaling in bone development and homeostasis.
abstract: The balance between bone formation and bone resorption controls postnatal bone homeostasis. Research over the last decade has provided a vast amount of evidence that WNT signaling plays a pivotal role in regulating this balance. Therefore, understanding how the WNT signaling pathway regulates skeletal development and homeostasis is of great value for human skeletal health and disease.
authors.affiliation: Center for Skeletal Disease and Tumor Microenvironment, Van Andel Research Institute, Grand Rapids, MI, USA.
authors.forename: Zhendong
authors.initials: Z
authors.lastname: Zhong
authors.forename: Nicole J
authors.initials: NJ
authors.lastname: Ethen
authors.forename: Bart O
authors.initials: BO
authors.lastname: Williams
mesh_terms: D000818:Animals; D001846:Bone Development; D001847:Bone Diseases / Q000378:metabolism / Q000473:pathology; D019070:Cell Lineage; D006706:Homeostasis; D006801:Humans; D010006:Osteoblasts / Q000378:metabolism / Q000473:pathology; D060449:Wnt Signaling Pathway