title: Burned to the bone.
abstract: Heterotopic ossification--a complication of severe burns, head or blast injuries, and orthopaedic trauma--can result from altered adenosine metabolism in mesenchymal stem cells in response to elevated extracellular ATP (Peterson et al., this issue).
authors.affiliation: Regenerative Medicine Department, Naval Medical Research Center, Silver Spring, MD 20910, USA.
authors.forename: Jonathan A
authors.initials: JA
authors.lastname: Forsberg
authors.affiliation: Regenerative Medicine Department, Naval Medical Research Center, Silver Spring, MD 20910, USA.
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Davis
authors.affiliation: Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
authors.forename: Eric A
authors.initials: EA
authors.lastname: Elster
authors.affiliation: LaCell, New Orleans, LA 70112, USA. Center for Stem Cell Research and Regenerative Medicine, School of Medicine, Tulane University, New Orleans, LA 70112, USA. Department of Medicine, School of Medicine, Tulane University, New Orleans, LA 70112, USA. Department of Surgery, School of Medicine, Tulane University, New Orleans, LA 70112, USA. jgimble@tulane.edu.
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Gimble
mesh_terms: D000125:Achilles Tendon / Q000187:drug effects*; D000255:Adenosine Triphosphate / Q000378:metabolism*; D000818:Animals; D001081:Apyrase / Q000494:pharmacology*; D002056:Burns / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D059630:Mesenchymal Stem Cells / Q000187:drug effects*; D009999:Ossification, Heterotopic / Q000188:drug therapy*; D010012:Osteogenesis / Q000187:drug effects*
chemical_list: D000255:Adenosine Triphosphate; D001081:Apyrase