title: Genome-wide association study of intracranial aneurysm identifies a new association on chromosome 7.
abstract: OBJECTIVE
  Common variants have been identified using genome-wide association studies which contribute to intracranial aneurysms (IA) susceptibility. However, it is clear that the variants identified to date do not account for the estimated genetic contribution to disease risk.
  
  
  METHODS
  Initial analysis was performed in a discovery sample of 2617 IA cases and 2548 controls of white ancestry. Novel chromosomal regions meeting genome-wide significance were further tested for association in 2 independent replication samples: Dutch (717 cases; 3004 controls) and Finnish (799 cases; 2317 controls). A meta-analysis was performed to combine the results from the 3 studies for key chromosomal regions of interest.
  
  
  RESULTS
  Genome-wide evidence of association was detected in the discovery sample on chromosome 9 (CDKN2BAS; rs10733376: P<1.0×10(-11)), in a gene previously associated with IA. A novel region on chromosome 7, near HDAC9, was associated with IA (rs10230207; P=4.14×10(-8)). This association replicated in the Dutch sample (P=0.01) but failed to show association in the Finnish sample (P=0.25). Meta-analysis results of the 3 cohorts reached statistical significant (P=9.91×10(-10)).
  
  
  CONCLUSIONS
  We detected a novel region associated with IA susceptibility that was replicated in an independent Dutch sample. This region on chromosome 7 has been previously associated with ischemic stroke and the large vessel stroke occlusive subtype (including HDAC9), suggesting a possible genetic link between this stroke subtype and IA.
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.). tforoud@iu.edu.
authors.forename: Tatiana
authors.initials: T
authors.lastname: Foroud
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Dongbing
authors.initials: D
authors.lastname: Lai
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Daniel
authors.initials: D
authors.lastname: Koller
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Femke
authors.initials: F
authors.lastname: Van't Hof
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Mitja I
authors.initials: MI
authors.lastname: Kurki
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Craig S
authors.initials: CS
authors.lastname: Anderson
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Robert D
authors.initials: RD
authors.lastname: Brown
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Edward Sander
authors.initials: ES
authors.lastname: Connolly
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Johan G
authors.initials: JG
authors.lastname: Eriksson
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Matthew
authors.initials: M
authors.lastname: Flaherty
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Myriam
authors.initials: M
authors.lastname: Fornage
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Mikael
authors.initials: M
authors.lastname: von Und Zu Fraunberg
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Emília I
authors.initials: EI
authors.lastname: Gaál
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Aki
authors.initials: A
authors.lastname: Laakso
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Juha
authors.initials: J
authors.lastname: Hernesniemi
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: John
authors.initials: J
authors.lastname: Huston
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Juha E
authors.initials: JE
authors.lastname: Jääskeläinen
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Lambertus A
authors.initials: LA
authors.lastname: Kiemeney
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Riku
authors.initials: R
authors.lastname: Kivisaari
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Dawn
authors.initials: D
authors.lastname: Kleindorfer
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Nerissa
authors.initials: N
authors.lastname: Ko
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Hanna
authors.initials: H
authors.lastname: Lehto
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Jason
authors.initials: J
authors.lastname: Mackey
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Irene
authors.initials: I
authors.lastname: Meissner
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Charles J
authors.initials: CJ
authors.lastname: Moomaw
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Thomas H
authors.initials: TH
authors.lastname: Mosley
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Marek
authors.initials: M
authors.lastname: Moskala
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Mika
authors.initials: M
authors.lastname: Niemelä
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Aarno
authors.initials: A
authors.lastname: Palotie
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Joanna
authors.initials: J
authors.lastname: Pera
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Gabriel
authors.initials: G
authors.lastname: Rinkel
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Stephan
authors.initials: S
authors.lastname: Ripke
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Guy
authors.initials: G
authors.lastname: Rouleau
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Ynte
authors.initials: Y
authors.lastname: Ruigrok
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Laura
authors.initials: L
authors.lastname: Sauerbeck
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Słowik
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Sita H
authors.initials: SH
authors.lastname: Vermeulen
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Daniel
authors.initials: D
authors.lastname: Woo
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Bradford B
authors.initials: BB
authors.lastname: Worrall
authors.affiliation: From the Indiana University School of Medicine, Indianapolis (T.F., D.L., D.K., J.M.); University Medical Center Utrecht, Utrecht, The Netherlands (F.v.H., G.R., Y.R.); Kuopio University Hospital, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); University of Eastern Finland, Kuopio, Finland (M.I.K., M.v.u.z.F., J.E.J.); Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K., A.P., S.R.); Broad Institute of Harvard and MIT, Cambridge, MA (M.I.K., A.P., S.R.); University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia (C.S.A.); Mayo Clinic, Rochester, MN (R.D.B., J. Huston I.M.); Columbia University School of Medicine, New York, NY (E.S.C.); University of Helsinki, Helsinki, Finland (J.G.E., E.I.G.); Folkhälsan Research Center, Helsinki, Finland (J.G.E.); National Institute for Health and Welfare, Helsinki, Finland (J.G.E.); Vasa Central Hospital, Vasa, Finland (J.G.E.); Helsinki University Central Hospital, Helsinki, Finland (J.G.E., E.I.G., A.L., J. Hernesniemi, R.K., H.L., M.N.); University of Cincinnati, OH (M. Flaherty, D.K., C.J.M., L.S., D.W., J.B.); University of Texas Health Science Center at Houston (M. Fornage); Radboud University Medical Center, Nijmegen, The Netherlands (L.A.K., S.H.V.); University of California, San Francisco (N.K.); University of Mississippi Medical Center, Jackson (T.H.M.); Jagiellonian University Medical College, Krakow, Poland (M.M., J.P., A.S.); The Wellcome Trust Sanger Institute, Cambridge, United Kingdom (A.P.); University of Montreal, Montréal, Québec, Canada (G.R.); and University of Virginia School of Medicine, Charlottesville (B.B.W.).
authors.forename: Joseph
authors.initials: J
authors.lastname: Broderick
mesh_terms: D000328:Adult; D000368:Aged; D002897:Chromosomes, Human, Pair 7 / Q000235:genetics*; D015331:Cohort Studies; D005260:Female; D055106:Genome-Wide Association Study / Q000379:methods*; D006801:Humans; D002532:Intracranial Aneurysm / Q000175:diagnosis / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D044465:White People / Q000235:genetics*
keywords: chromosomes, human, pair 7; genome-wide association study; intracranial aneurysm