title: Effect of calcium hydroxide and double and triple antibiotic pastes on the bond strength of epoxy resin-based sealer to root canal dentin.
abstract: BACKGROUND
  The aim of this study was to evaluate the effects of calcium hydroxide (CH) and triple (TAP) and double (DAP) antibiotic pastes on the bond strength of an epoxy resin-based sealer (AH Plus Jet; Dentsply DeTrey, Konstanz, Germany) to the root canal dentin.
  
  
  METHODS
  Sixty-four single-rooted human mandibular premolars were decoronated and prepared using the rotary system to size 40. The specimens were randomly divided into a control group (without intracanal dressing) and 3 experimental groups that received an intracanal dressing with either CH, DAP, or TAP (n = 16). The intracanal dressing was removed by rinsing with 10 mL 17% EDTA followed by 10 mL 2.5% sodium hypochlorite. The root canals were then obturated with gutta-percha and AH Plus Jet sealer. A push-out test was used to measure the bond strength between the root canal dentin and the sealer. The data were analyzed using 2-way analysis of variance and Tukey post hoc tests to detect the effect of the independent variables (intracanal medicaments and root canal thirds) and their interactions on the push-out bond strength of the root canal filling material to the root dentin (P = .05).
  
  
  RESULTS
  The push-out bond strength values were significantly affected by the intracanal medicaments (P < .001) but not by the root canal thirds (P > .05). In the middle and apical third, the bond strength of the TAP group was higher than those of the CH and DAP groups (P < .05).
  
  
  CONCLUSIONS
  The DAP and CH did not affect the bond strength of the epoxy resin-based sealer. Additionally, the TAP improved the bond strength of the epoxy resin-based sealer in the middle and apical thirds.
authors.affiliation: Department of Pediatric Dentistry, Faculty of Dentistry, İzmir Katip Çelebi University, İzmir, Turkey. Electronic address: merve.akcay@ikc.edu.tr.
authors.forename: Merve
authors.initials: M
authors.lastname: Akcay
authors.affiliation: Department of Endodontics, Faculty of Dentistry, Ataturk University, Erzurum, Turkey.
authors.forename: Hakan
authors.initials: H
authors.lastname: Arslan
authors.affiliation: Department of Endodontics, Faculty of Dentistry, Erciyes University, İzmir, Turkey.
authors.forename: Hüseyin Sinan
authors.initials: HS
authors.lastname: Topcuoglu
authors.affiliation: Department of Endodontics, Faculty of Dentistry, Erciyes University, İzmir, Turkey.
authors.forename: Oznur
authors.initials: O
authors.lastname: Tuncay
mesh_terms: D000268:Adhesiveness; D000465:Algorithms; D000900:Anti-Bacterial Agents / Q000737:chemistry*; D002126:Calcium Hydroxide / Q000737:chemistry*; D002939:Ciprofloxacin / Q000737:chemistry; D001840:Dental Bonding; D003786:Dental Pulp Cavity / Q000648:ultrastructure*; D003799:Dental Stress Analysis / Q000295:instrumentation; D003804:Dentin / Q000648:ultrastructure*; D004492:Edetic Acid / Q000737:chemistry; D004853:Epoxy Resins / Q000737:chemistry*; D006171:Gutta-Percha / Q000737:chemistry; D006801:Humans; D008422:Materials Testing; D008795:Metronidazole / Q000737:chemistry; D008911:Minocycline / Q000737:chemistry; D011897:Random Allocation; D012387:Root Canal Filling Materials / Q000737:chemistry*; D012388:Root Canal Irrigants / Q000737:chemistry; D018915:Root Canal Preparation / Q000295:instrumentation / Q000379:methods; D012973:Sodium Hypochlorite / Q000737:chemistry; D013314:Stress, Mechanical; D013499:Surface Properties; D013997:Time Factors; D019227:Tooth Apex / Q000648:ultrastructure
chemical_list: D000900:Anti-Bacterial Agents; D004853:Epoxy Resins; D012387:Root Canal Filling Materials; D012388:Root Canal Irrigants; C534916:epoxy resin-based root canal sealer; D008795:Metronidazole; D002939:Ciprofloxacin; D006171:Gutta-Percha; D004492:Edetic Acid; D012973:Sodium Hypochlorite; D008911:Minocycline; D002126:Calcium Hydroxide
keywords: Bond strength; calcium hydroxide; double antibiotic paste; minocycline; resin-based sealer; triple antibiotic paste