title: [Survival and neurological outcome in out-of-hospital cardiac arrests due to shockable rhythms treated with mild therapeutic hypothermia].
abstract: OBJECTIVE
  To analyze survival and neurological outcome at short and medium term in patients treated with mild therapeutic hypothermia (HTM) in our hospital after suffering an out-of-hospital cardiac arrest (CA) secondary to a shockable rhythm.
  
  
  METHODS
  Prospective, observational study from September 1, 2010 to December 31, 2012, with a follow up of 6 months.
  
  
  METHODS
  Tertiary hospital.
  
  
  METHODS
  All patients who suffer an out-of-hospital CA due to shockable rhythms.
  
  
  METHODS
  non-shockable rhythms, resuscitation >45 minutes without pulse recovery, septic shock, previous coagulopathy, terminal illness or order for withholding treatment.
  
  
  METHODS
  Mild hypothermia (33°C) and postresuscitation care on the basis of standardized protocols.
  
  
  METHODS
  Demographic and epidemiological data, CA data and survival and neurological outcome at hospital discharge and after 6 months. To assess the patients' neurological status, Cerebral Performance Categories (CPC) scale was used.
  
  
  RESULTS
  A total of 54 patients were analyzed. 37 patients were discharged to hospital, representing a survival at discharge of 68.5%, which remains 6 months later because no discharged patient died during the follow up period. Regarding neurological outcome, 44.4% of patients were alive and with CPC 1-2 at discharge and up to 54.71% at 6 months.
  
  
  CONCLUSIONS
  The results of survival and neurological functional status obtained in our center after implementation of HTM are comparable to those published in the literature.
authors.affiliation: Servicio de Anestesiología y Reanimación, Hospital Clínic, Barcelona, España. Electronic address: mmagaldi@clinic.ub.es.
authors.forename: M
authors.initials: M
authors.lastname: Magaldi
authors.affiliation: Servicio de Anestesiología y Reanimación, Hospital Clínic, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Fontanals
authors.affiliation: Servicio de Anestesiología y Reanimación, Hospital Clínic, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Moreno
authors.affiliation: Servicio de Anestesiología y Reanimación, Hospital Clínic, Barcelona, España.
authors.forename: A
authors.initials: A
authors.lastname: Ruiz
authors.affiliation: Servicio de Medicina Interna, área de Vigilancia Intensiva, Hospital Clínic, Barcelona, España.
authors.forename: J M
authors.initials: JM
authors.lastname: Nicolás
authors.affiliation: Servicio de Cardiología, Unidad Coronaria, Hospital Clínic, Barcelona, España.
authors.forename: X
authors.initials: X
authors.lastname: Bosch
mesh_terms: D005260:Female; D006801:Humans; D007036:Hypothermia, Induced; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000209:etiology; D058687:Out-of-Hospital Cardiac Arrest / Q000150:complications / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D011379:Prognosis; D011446:Prospective Studies; D015996:Survival Rate; D017180:Tachycardia, Ventricular / Q000150:complications; D016896:Treatment Outcome; D014693:Ventricular Fibrillation / Q000150:complications
keywords: Cuidados postresucitación; Hipotermia terapéutica moderada; Mild therapeutic hypothermia; Neurological outcome; Out-of-hospital cardiac arrest; Parada cardiorrespiratoria extrahospitalaria; Post-resuscitation care; Pronóstico neurológico; Ritmos desfibrilables; Shockable rhythms; Supervivencia; Survival