title: A solid target system with remote handling of irradiated targets for PET cyclotrons.
abstract: A solid target system was developed for a PET cyclotron. The system is compatible with many different target materials in the form of foils and electroplated/sputtered targets which makes it useful for production of a wide variety of different PET radionuclides. The target material is manually loaded into the system. Remote handling of irradiated target material is managed with a pneumatic piston and a vacuum technique which allows the targets to be dropped into a shielded transport container. To test the target performance, proton irradiations (12.8 MeV, 45 μA) of monoisotopic yttrium foils (0.64 mm, direct water cooling) were performed to produce 89Zr. The yields were 2200±200 MBq (1 h, n=13) and 6300±65 MBq (3 h, n=3).
authors.affiliation: Department of Medical Radiation Physics, Clinical Sciences, Lund University, Skane University Hospital, Barngatan 2:1, 221 85 Lund, Sweden; Radiation Physics, Skåne University Hospital, 221 85 Lund, Sweden. Electronic address: jonathan.siikanen@med.lu.se.
authors.forename: J
authors.initials: J
authors.lastname: Siikanen
authors.affiliation: Lund University Bioimaging Center, Lund University, Faculty of Medicine, 221 84 Lund, Sweden.
authors.forename: T A
authors.initials: TA
authors.lastname: Tran
authors.affiliation: Radiation Physics, Skåne University Hospital, 221 85 Lund, Sweden.
authors.forename: T G
authors.initials: TG
authors.lastname: Olsson
authors.affiliation: Department of Medical Radiation Physics, Clinical Sciences, Lund University, Skane University Hospital, Barngatan 2:1, 221 85 Lund, Sweden; Radiation Physics, Skåne University Hospital, 221 85 Lund, Sweden.
authors.forename: S-E
authors.initials: SE
authors.lastname: Strand
authors.affiliation: Radiation Physics, Skåne University Hospital, 221 85 Lund, Sweden.
authors.forename: A
authors.initials: A
authors.lastname: Sandell
mesh_terms: D017357:Cyclotrons / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D007553:Isotope Labeling / Q000295:instrumentation*; D049268:Positron-Emission Tomography / Q000295:instrumentation*; D011829:Radiation Dosage; D011868:Radioisotopes / Q000737:chemistry* / Q000528:radiation effects; D011874:Radiometry / Q000295:instrumentation; D012371:Robotics / Q000295:instrumentation*; D013048:Specimen Handling / Q000295:instrumentation*; D015040:Zirconium / Q000737:chemistry* / Q000528:radiation effects
chemical_list: D011868:Radioisotopes; D015040:Zirconium