title: Palladium-catalyzed N-nitroso-directed C-H alkoxylation of arenes and subsequent formation of 2-alkoxy-N-alkylarylamines.
abstract: A palladium-catalyzed direct ortho-alkoxylation of N-alkyl-N-nitrosoarylamines was developed in which alcohols were used as the alkoxylation reagents and PhI(OAc)2 was employed as the oxidant. The protocol was available for both primary and secondary alcohols. The products were transformed to o-alkoxy-N-alkylanilines expediently by a simple reduction.
authors.affiliation: Jiangsu Key Laboratory of Biofunctional Materials, Jiangsu Provincial Key Laboratory of Material Cycle Processes and Pollution Control, College of Chemistry and Materials Science, Nanjing Normal University , Nanjing 210097, China.
authors.forename: Tingting
authors.initials: T
authors.lastname: Gao
authors.forename: Peipei
authors.initials: P
authors.lastname: Sun
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D002384:Catalysis; D006860:Hydrogen Bonding; D007202:Indicators and Reagents / Q000737:chemistry*; D015394:Molecular Structure; D009603:Nitroso Compounds / Q000737:chemistry*; D016877:Oxidants / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D000438:Alcohols; D007202:Indicators and Reagents; D009603:Nitroso Compounds; D016877:Oxidants; C059688:alkoxyl radical; D010165:Palladium