title: Prevalence and distribution of oral mucosal lesions: a cross-sectional study in Shanghai, China.
abstract: BACKGROUND
  An epidemiological study on the oral mucosal lesions (OMLs) in general population from China was scarce. The objective of this study was to investigate the prevalence and distribution of OMLs in Shanghai, China and to evaluate their association with demographic factors and smoking/drinking habits based on a large scaled population on a wide spectrum.
  
  
  METHODS
  In this population-based cross-sectional study, 11054 community-dwelling individuals (M/F: 5140/5914; age range, 1-96 years) were randomly selected and examined according to WHO criteria.
  
  
  RESULTS
  The prevalence of OMLs was 10.8% in this study. A total of 1192 (M/F: 543/649; mean age, 56.9 years) individuals were presented with different types of OMLs. The most common type of OMLs was fissured tongue (prevalence of 3.15%), followed by recurrent aphthae (1.48%), traumatic ulcer (1.13%), and angular cheilitis (0.86%). The two most common potentially malignant disorders were oral lichen planus (0.81%) and leukoplakia (0.22%). Regression analysis revealed that the elderly age, smoking, and alcohol intake were statistically significant risk factors of OMLs with emphasis on leukokeratosis, leukoplakia, and lichen planus.
  
  
  CONCLUSIONS
  The prevalence and distribution of OMLs were elucidated in an eastern area of China, and the importance of tobacco and alcohol in the pathogenesis of OMLs was evidenced. Our data have provided baseline information about epidemiologic aspects of OMLs that can be valuable in organized program targeting on oral health and hygiene.
authors.affiliation: Department of Preventive Dentistry, Shanghai Stomatological Disease Center, Shanghai, China.
authors.forename: Jinqiu
authors.initials: J
authors.lastname: Feng
authors.affiliation: Department of Oral Mucosal Diseases, Shanghai Key Laboratory of Stomatology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
authors.forename: Zengtong
authors.initials: Z
authors.lastname: Zhou
authors.affiliation: Department of Oral Mucosal Diseases, Shanghai Key Laboratory of Stomatology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
authors.forename: Xuemin
authors.initials: X
authors.lastname: Shen
authors.affiliation: Department of Oral Mucosal Diseases, Shanghai Key Laboratory of Stomatology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
authors.forename: Yufeng
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Oral Mucosal Diseases, Shanghai Key Laboratory of Stomatology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
authors.forename: Linjun
authors.initials: L
authors.lastname: Shi
authors.affiliation: Shanghai Dental Diseases Prevention and Cure Center of YangPu District, Shanghai, China.
authors.forename: Yijun
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Shanghai Dental Diseases Prevention and Cure Center of MinHang District, Shanghai, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Hu
authors.affiliation: Department of Stomatology, Huashan Hospital, Fudan University, Shanghai, China.
authors.forename: Hongying
authors.initials: H
authors.lastname: Sun
authors.affiliation: Department of Oral Mucosal Diseases, Shanghai Key Laboratory of Stomatology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000428:Alcohol Drinking / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007223:Infant; D007971:Leukoplakia / Q000453:epidemiology / Q000209:etiology; D007972:Leukoplakia, Oral / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000453:epidemiology*; D009062:Mouth Neoplasms / Q000453:epidemiology; D009909:Oral Health; D015995:Prevalence; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000453:epidemiology; D013281:Stomatitis, Aphthous / Q000453:epidemiology / Q000209:etiology; D014063:Tongue, Fissured / Q000453:epidemiology / Q000209:etiology; D055815:Young Adult
keywords: Chinese population; epidemiology; oral mucosal lesions; prevalence; risk factors