title: Cancer Core Europe: a consortium to address the cancer care-cancer research continuum challenge.
abstract: European cancer research for a transformative initiative by creating a consortium of six leading excellent comprehensive cancer centres that will work together to address the cancer care-cancer research continuum. Prerequisites for joint translational and clinical research programs are very demanding. These require the creation of a virtual single 'e-hospital' and a powerful translational platform, inter-compatible clinical molecular profiling laboratories with a robust underlying computational biology pipeline, standardised functional and molecular imaging, commonly agreed Standard Operating Procedures (SOPs) for liquid and tissue biopsy procurement, storage and processing, for molecular diagnostics, 'omics', functional genetics, immune-monitoring and other assessments. Importantly also it requires a culture of data collection and data storage that provides complete longitudinal data sets to allow for: effective data sharing and common database building, and to achieve a level of completeness of data that is required for conducting outcome research, taking into account our current understanding of cancers as communities of evolving clones. Cutting edge basic research and technology development serve as an important driving force for innovative translational and clinical studies. Given the excellent track records of the six participants in these areas, Cancer Core Europe will be able to support the full spectrum of research required to address the cancer research- cancer care continuum. Cancer Core Europe also constitutes a unique environment to train the next generation of talents in innovative translational and clinical oncology.
authors.affiliation: Gustave Roussy Cancer Campus Grand Paris, Villejuif, France. Electronic address: alexander.eggermont@gustaveroussy.fr.
authors.forename: Alexander M M
authors.initials: AM
authors.lastname: Eggermont
authors.affiliation: Cambridge Cancer Centre, Cambridge, United Kingdom.
authors.forename: Carlos
authors.initials: C
authors.lastname: Caldas
authors.affiliation: Karolinska Insititutet, Stockholm, Sweden.
authors.forename: Ulrik
authors.initials: U
authors.lastname: Ringborg
authors.affiliation: Netherlands Cancer Institute (NKI), Amsterdam, The Netherlands.
authors.forename: René
authors.initials: R
authors.lastname: Medema
authors.affiliation: Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.
authors.forename: Josep
authors.initials: J
authors.lastname: Tabernero
authors.affiliation: National Center for Tumour Diseases (DKFZ-NCT), Heidelberg, Germany.
authors.forename: Otmar
authors.initials: O
authors.lastname: Wiestler
mesh_terms: D035843:Biomedical Research / Q000458:organization & administration; D002173:Cancer Care Facilities / Q000458:organization & administration*; D005060:Europe; D006801:Humans; D007373:Interinstitutional Relations; D007391:International Cooperation; D008495:Medical Oncology / Q000458:organization & administration*; D009369:Neoplasms / Q000628:therapy*; D016730:Program Development; D057170:Translational Research, Biomedical / Q000458:organization & administration
keywords: Cancer care; Consortium; Continuum; Europe; Research