title: Practical application of flavonoid-poor menu meals to the study of the bioavailability of bilberry anthocyanins in human subjects.
abstract: Practical application of flavonoid-poor menus was evaluated on the bioavailability of anthocyanins as model flavonoids. Detectable amounts of flavonoids were not found in plasma and urine collected from 13 participants, who took the menus. After ingesting bilberry anthocyanins (919 μmol), average plasma AUC0-6h, Cmax, Tmax values and urinary recovery were 386.0 nmol h/mL, 139.1 nM, 1.31 h and 0.21%, respectively.
authors.affiliation: a Faculty of Agriculture , University of Miyazaki , Miyazaki , Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Sakakibara
authors.forename: Yoko
authors.initials: Y
authors.lastname: Ichikawa
authors.forename: Sanae
authors.initials: S
authors.lastname: Tajima
authors.forename: Yoshie
authors.initials: Y
authors.lastname: Makino
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Wakasugi
authors.forename: Kayoko
authors.initials: K
authors.lastname: Shimoi
authors.forename: Saori
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Shigenori
authors.initials: S
authors.lastname: Kumazawa
authors.forename: Toshinao
authors.initials: T
authors.lastname: Goda
mesh_terms: D000328:Adult; D000872:Anthocyanins / Q000097:blood / Q000493:pharmacokinetics* / Q000652:urine; D001682:Biological Availability; D005419:Flavonoids / Q000032:analysis*; D006801:Humans; D008297:Male; D062407:Meals; D013997:Time Factors; D029800:Vaccinium myrtillus / Q000737:chemistry*
chemical_list: D000872:Anthocyanins; D005419:Flavonoids
keywords: bilberry anthocyanins; bioavailability; dietary reference intake; flavonoid-poor menu meals; human study