title: Validity and clinical interpretability of Overall Anxiety Severity And Impairment Scale (OASIS).
abstract: BACKGROUND
  The Overall Anxiety Severity and Impairment Scale is a brief generic measure for anxiety that encompasses frequency and intensity as well as behavioral and functional aspects of anxiety. This study was conducted to elucidate aspects of reliability, validity, and interpretability, such as equivalence of factor loadings across non-clinical and clinical populations, convergence and discriminance of related variables, and performance of detecting diagnostic and medical status of anxiety disorders.
  
  
  METHODS
  Non-clinical and clinical Japanese populations were taken from a panelist pool registered with an internet survey company (total n=2830; 619 panic disorder, 576 for social anxiety disorder, 645 for obsessive-compulsive disorder, a 619 for major depressive disorder, and 371 for non-disorder panelists). Conventional measures of anxiety, depression, mental health and measures for discriminant validity were administered in addition to OASIS.
  
  
  RESULTS
  Exploratory and confirmatory factor analyses indicated good fit to data for the one-factor model of OASIS. Multi-group confirmatory factor analysis showed the equivalence of the factor loadings between those of non-clinical and clinical subsamples. The OASIS reliability was confirmed by internal consistency and test-retest coefficients. Receiver operating characteristic curve analyses showed that OASIS and conventional anxiety measures have fair performance for detecting diagnostic and medical status as anxiety disorders.
  
  
  CONCLUSIONS
  Participants were limited to a Japanese population of people who had registered themselves at an internet survey company.
  
  
  CONCLUSIONS
  Along with useful information to interpret OASIS, the results suggest the reliability and validity of OASIS in Japanese populations. These results also suggest cross-cultural validity.
authors.affiliation: National Center for Cognitive Behavior Therapy and Research, National Center of Neurology and Psychiatry, Japan. Electronic address: masayait@ncnp.go.jp.
authors.forename: Masaya
authors.initials: M
authors.lastname: Ito
authors.affiliation: National Institute of Mental Health, National Center of Neurology and Psychiatry, Japan.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Oe
authors.affiliation: National Center for Cognitive Behavior Therapy and Research, National Center of Neurology and Psychiatry, Japan.
authors.forename: Noriko
authors.initials: N
authors.lastname: Kato
authors.affiliation: Tokyo Medical University, Japan.
authors.forename: Shun
authors.initials: S
authors.lastname: Nakajima
authors.affiliation: University of Tsukuba, Japan.
authors.forename: Hiroko
authors.initials: H
authors.lastname: Fujisato
authors.affiliation: University of Tsukuba, Japan.
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Miyamae
authors.affiliation: National Center of Neurology and Psychiatry, Japan.
authors.forename: Ayako
authors.initials: A
authors.lastname: Kanie
authors.affiliation: National Center for Cognitive Behavior Therapy and Research, National Center of Neurology and Psychiatry, Japan.
authors.forename: Masaru
authors.initials: M
authors.lastname: Horikoshi
authors.affiliation: National Center for PTSD, VA Center of Excellence for Stress and Mental Health, UCSD Department of Psychiatry, USA.
authors.forename: Sonya B
authors.initials: SB
authors.lastname: Norman
mesh_terms: D000328:Adult; D000368:Aged; D001007:Anxiety / Q000523:psychology*; D044466:Asian People; D003469:Culture; D004185:Disability Evaluation; D005163:Factor Analysis, Statistical; D005239:Fear / Q000523:psychology; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000523:psychology; D010549:Personal Satisfaction; D010556:Personality Tests; D015203:Reproducibility of Results; D012959:Socioeconomic Factors; D055815:Young Adult
keywords: Anxiety disorders; Culture; Factor analysis; Reliability; Validity