title: A new approach for the synthesis of bisindoles through AgOTf as catalyst.
abstract: A novel approach for the catalyzed formation of bisindolylmethane derivatives (BIMs) is described. This methodology is the unique example where AgOTf has been successfully used for the activation of aldehydes, giving easy access to a broad range of bisindolyl derivatives with excellent results. Moreover, the simplicity and easy operational methodology using a small amount of commercially available AgOTf (1-3 mol %), one of the lowest catalytic charge used in this process to date, makes this procedure an alternative approach for this interesting and appealing reaction.
authors.affiliation: Departamento de Química Inorgánica. Instituto de Síntesis Química y Catálisis Homogénea (ISQCH), CSIC-Universidad de Zaragoza. E-50009 Zaragoza, Spain.
authors.forename: Jorge
authors.initials: J
authors.lastname: Beltrá
authors.affiliation: Departamento de Química Inorgánica. Instituto de Síntesis Química y Catálisis Homogénea (ISQCH), CSIC-Universidad de Zaragoza. E-50009 Zaragoza, Spain.
authors.forename: M Concepción
authors.initials: MC
authors.lastname: Gimeno
authors.affiliation: Departamento de Química Orgánica. Instituto de Síntesis Química y Catálisis Homogénea (ISQCH), CSIC-Universidad de Zaragoza. E-50009 Zaragoza, Spain.
authors.forename: Raquel P
authors.initials: RP
authors.lastname: Herrera
keywords: Ag(I); aldehydes; bisindole; catalysis; indole