title: The alteration of NTproCNP plasma levels following anaerobic exercise in physically active young men.
abstract: OBJECTIVE
  Amino-terminal propeptide of C-type natriuretic peptide (NTproCNP) is a synthesis product of C-type natriuretic peptide (CNP). In this study, plasma levels of NTproCNP were compared before and after exercise in healthy young subjects who are physically active (PA) or not physically active (NPA).
  
  
  METHODS
  The study was carried on PA group (n=10) who defined the exercise duration more than 2.5 hours per week for at least one year and NPA group (n = 10) whose exercise duration was lower than 1.5 hours per week. The level of maximal oxygen consumption was determined. Wingate exercise test was applied on the following day. Plasma NTproCNP levels were measured before the exercise and at the 1st, 5th and 30th minute after the exercise.
  
  
  RESULTS
  Exercise duration of physically active group was reported as 11.3 ± 5.0 hours per week. Basal NTproCNP levels of the groups were found to be comparable. NTproCNP levels in the 5th minute (0.93 ± 0.23 pmol/L; p<0.05) and in the 30th minute (0.77 ± 0.21 pmol/L p < 0.05) after exercise were higher than the levels before exercise (0.64 ± 0.29 pmol/L) in PA group. Additionally, the plasma levels of NTproCNP after 5th minute of exercise were higher in PA group (0.93 ± 0.23 pmol/L) than NPA group (0.74 ± 0.16 pmol/L, p<0.05).
  
  
  CONCLUSIONS
  Being physically active may be a fact affecting the secretion of CNP, which plays a protective role in endothelium, following exercise.
authors.affiliation: Department of Physiology, Faculty of Medicine, Trakya University; Edirne-Turkey. arzuvardar22@hotmail.com.
authors.forename: Hilal
authors.initials: H
authors.lastname: Akseki Temür
authors.forename: Selma Arzu
authors.initials: SA
authors.lastname: Vardar
authors.forename: Muzaffer
authors.initials: M
authors.lastname: Demir
authors.forename: Orkide
authors.initials: O
authors.lastname: Palabıyık
authors.forename: Aziz
authors.initials: A
authors.lastname: Karaca
authors.forename: Zuhal
authors.initials: Z
authors.lastname: Guksu
authors.forename: Arif
authors.initials: A
authors.lastname: Ortanca
authors.forename: Necdet
authors.initials: N
authors.lastname: Süt
mesh_terms: D000293:Adolescent; D001794:Blood Pressure; D015444:Exercise; D005080:Exercise Test; D006801:Humans; D008297:Male; D020098:Natriuretic Peptide, C-Type / Q000097:blood*; D012016:Reference Values; D055815:Young Adult
chemical_list: C480579:amino-terminal pro-C-type natriuretic peptide, human; D020098:Natriuretic Peptide, C-Type