title: Extramammary Paget disease: a report of 10 cases.
abstract: Extramammary Paget disease (EMPD) is a very rare form of intraepithelial adenocarcinoma. We report the cases of EMPD diagnosed in a referral hospital over a 5-year period from 2009 to 2013. Ten cases of EMPD were diagnosed in 4 men and 6 women aged between 50 and 79 years. Erroneous clinical diagnoses led to diagnostic delays of 1 to 5 years in all cases. Six patients had in situ lesions and dermal invasion was observed in the other 4 cases. Four patients had a second neoplasm and 2 of the patients with invasive EMPD died. Because EMPD is rare and its clinical presentation is nonspecific, a high degree of clinical suspicion is required to avoid delays in diagnosis and treatment.
authors.affiliation: Unidad de Gestión Clínica, Dermatología Médico Quirúrgica y Venereología, Hospital Universitario Virgen de las Nieves, Granada, España. Electronic address: gonzaloblascomorente@gmail.com.
authors.forename: G
authors.initials: G
authors.lastname: Blasco-Morente
authors.affiliation: Anatomía Patológica, Hospital Universitario Virgen de las Nieves, Granada, España.
authors.forename: A
authors.initials: A
authors.lastname: Martín-Castro
authors.affiliation: Unidad de Gestión Clínica, Dermatología Médico Quirúrgica y Venereología, Hospital Universitario Virgen de las Nieves, Granada, España.
authors.forename: C
authors.initials: C
authors.lastname: Garrido-Colmenero
authors.affiliation: Unidad de Gestión Clínica, Dermatología Médico Quirúrgica y Venereología, Hospital Universitario Virgen de las Nieves, Granada, España.
authors.forename: J
authors.initials: J
authors.lastname: Tercedor-Sánchez
mesh_terms: D000368:Aged; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010145:Paget Disease, Extramammary / Q000175:diagnosis / Q000473:pathology
keywords: Adenocarcinoma; Enfermedad de Paget extramamaria; Extramammary Paget disease; Rare tumor; Tumor raro