title: Evaluation of the making sense of brain tumor program: a randomized controlled trial of a home-based psychosocial intervention.
abstract: OBJECTIVE
  Despite significant psychosocial morbidity, there are few controlled trials of psychological support for people with brain tumor. This study evaluated the efficacy of the Making Sense of Brain Tumor (MSoBT) program, a home-based psychosocial intervention.
  
  
  METHODS
  A randomized controlled trial with a wait list condition
  
  
  METHODS
  Fifty participants aged 17-82 years with brain tumor (54% benign) were randomly allocated to immediate treatment (n = 27) or a waitlist (n = 23). Measures included Montgomery-Asberg Depression Rating Scale (MADRS), McGill Quality of Life (MQOL) Questionnaire, Depression Anxiety Stress Scales (DASS) and Functional Assessment of Cancer Therapy-Brain (FACT-Br). The immediate treatment group received the 10-session MSoBT program, while the waitlist group received usual care for 10 weeks and were then re-assessed before receiving the MSoBT program. A 6-month post-intervention follow-up was conducted.
  
  
  RESULTS
  Analysis of covariance adjusting for baseline functioning identified that the immediate treatment group reported significantly lower levels of depression on the MADRS (η(p)(2)  = .19) and higher levels of existential well-being on the MQOL (η(p)(2)  = .13) and functional well-being (η(p)(2)  = .21) and global quality of life on the FACT-Br (η(p)(2)  = .12) at post-assessment than the waitlist group. At 6-month follow-up participants reported significantly lower levels of depression and stress and higher existential well-being and quality of life relative to pre-intervention.
  
  
  CONCLUSIONS
  The MSoBT program appears to have efficacy for enhancing psychological well-being and quality of life after brain tumor.
authors.affiliation: School of Applied Psychology and Griffith Health Institute, Griffith University, Brisbane, Australia.
authors.forename: Tamara
authors.initials: T
authors.lastname: Ownsworth
authors.forename: Suzanne
authors.initials: S
authors.lastname: Chambers
authors.forename: Ea
authors.initials: E
authors.lastname: Damborg
authors.forename: Leanne
authors.initials: L
authors.lastname: Casey
authors.forename: David G
authors.initials: DG
authors.lastname: Walker
authors.forename: David H K
authors.initials: DH
authors.lastname: Shum
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001007:Anxiety / Q000523:psychology / Q000628:therapy*; D001932:Brain Neoplasms / Q000523:psychology*; D003863:Depression / Q000523:psychology / Q000628:therapy*; D005260:Female; D006699:Home Care Services; D006801:Humans; D008297:Male; D008875:Middle Aged; D010353:Patient Education as Topic / Q000379:methods*; D011613:Psychotherapy / Q000379:methods*; D011788:Quality of Life; D012944:Social Support; D013315:Stress, Psychological / Q000523:psychology / Q000628:therapy*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D055815:Young Adult
keywords: brain tumor; cancer; mental health; oncology; quality of life; randomized controlled trial