title: [Transdisciplinary Approach for Sarcopenia. Physical activity and sarcopenia].
abstract: With the goal of establishing epidemiologic indexes to evaluate the clinical evidence for developing a disease-modifying treatment of bone and joint diseases including sarcopenia, we set up a large-scale nationwide cohort study called ROAD (Research on Osteoarthritis/osteoporosis Against Disability) in 2005. We established muscle strength and volume indexes stratified according to gender and age strata. We also clarified the prevalence of sarcopenia and its association with osteoarthritis, pain, and exercise in middle-aged individuals. In addition, we showed that unipedal standing exercise and squatting are effective methods to prevent sarcopenia.
authors.affiliation: Department of Clinical Motor System Medicine, 22nd Century Medical and Research Center, the University of Tokyo, Japan.
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Muraki
mesh_terms: D000367:Age Factors; D015444:Exercise; D006801:Humans; D053580:Muscle Strength; D017410:Practice Guidelines as Topic; D015995:Prevalence; D055948:Sarcopenia / Q000175:diagnosis* / Q000503:physiopathology; D012727:Sex Characteristics