title: Recent trends of polymer mediated liposomal gene delivery system.
abstract: Advancement in the gene delivery system have resulted in clinical successes in gene therapy for patients with several genetic diseases, such as immunodeficiency diseases, X-linked adrenoleukodystrophy (X-ALD) blindness, thalassemia, and many more. Among various delivery systems, liposomal mediated gene delivery route is offering great promises for gene therapy. This review is an attempt to depict a portrait about the polymer based liposomal gene delivery systems and their future applications. Herein, we have discussed in detail the characteristics of liposome, importance of polymer for liposome formulation, gene delivery, and future direction of liposome based gene delivery as a whole.
authors.affiliation: Department of Physics, School of Basic and Applied Sciences, Galgotias University, Greater Noida 203201, India ; Department of Physics, Tokai University, Hiratsuka-Shi, Kanagawa 259-1292, Japan.
authors.forename: Shyamal Kumar
authors.identifier: 0000-0003-1538-7300
authors.initials: SK
authors.lastname: Kundu
authors.affiliation: Institute for Skeletal Aging & Orthopedic Surgery, Hallym University-Chuncheon Sacred Heart Hospital, Chuncheon 200704, Republic of Korea.
authors.forename: Ashish Ranjan
authors.identifier: 0000-0003-3973-6755
authors.initials: AR
authors.lastname: Sharma
authors.affiliation: Institute for Skeletal Aging & Orthopedic Surgery, Hallym University-Chuncheon Sacred Heart Hospital, Chuncheon 200704, Republic of Korea.
authors.forename: Sang-Soo
authors.initials: SS
authors.lastname: Lee
authors.affiliation: Institute for Skeletal Aging & Orthopedic Surgery, Hallym University-Chuncheon Sacred Heart Hospital, Chuncheon 200704, Republic of Korea.
authors.forename: Garima
authors.identifier: 0000-0003-1763-0730
authors.initials: G
authors.lastname: Sharma
authors.affiliation: Medical Biotechnology Division, School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu 632014, India.
authors.forename: C George Priya
authors.initials: CG
authors.lastname: Doss
authors.affiliation: Department of Physics, Tokai University, Hiratsuka-Shi, Kanagawa 259-1292, Japan.
authors.forename: Shin
authors.initials: S
authors.lastname: Yagihara
authors.affiliation: Institute for Skeletal Aging & Orthopedic Surgery, Hallym University-Chuncheon Sacred Heart Hospital, Chuncheon 200704, Republic of Korea.
authors.forename: Do-Young
authors.initials: DY
authors.lastname: Kim
authors.affiliation: Institute for Skeletal Aging & Orthopedic Surgery, Hallym University-Chuncheon Sacred Heart Hospital, Chuncheon 200704, Republic of Korea.
authors.forename: Ju-Suk
authors.identifier: 0000-0003-4437-3194
authors.initials: JS
authors.lastname: Nam
authors.affiliation: Institute for Skeletal Aging & Orthopedic Surgery, Hallym University-Chuncheon Sacred Heart Hospital, Chuncheon 200704, Republic of Korea ; Department of Bioinformatics, School of Computer Sciences, Galgotias University, Greater Noida 203201, India.
authors.forename: Chiranjib
authors.identifier: 0000-0002-3958-239X
authors.initials: C
authors.lastname: Chakraborty
mesh_terms: D004247:DNA / Q000008:administration & dosage* / Q000235:genetics*; D004339:Drug Compounding / Q000379:methods*; D015195:Drug Design; D008081:Liposomes / Q000737:chemistry*; D053769:Nanocapsules / Q000737:chemistry* / Q000648:ultrastructure; D010316:Particle Size; D011108:Polymers / Q000737:chemistry*; D014162:Transfection / Q000639:trends*
chemical_list: D008081:Liposomes; D053769:Nanocapsules; D011108:Polymers; D004247:DNA