title: Donor-transmitted malaria after heart transplant managed successfully with artesunate.
abstract: Donor-transmitted malaria is a rare complication in solid organ transplantation, which causes high mortality. Data concerning the use of artesunate in solid organ transplant recipients are lacking. We report a heart transplant patient who developed donor-derived severe Plasmodium falciparum malaria, successfully treated with artesunate. Transmission of malaria to 2 of the other transplant recipients from the same donor was also documented.
authors.affiliation: Infectious Disease Service, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) - Hospital Universitari de Bellvitge, University of Barcelona, Barcelona, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Sabé
authors.forename: J
authors.initials: J
authors.lastname: González-Costello
authors.forename: I
authors.initials: I
authors.lastname: Oriol
authors.forename: J C
authors.initials: JC
authors.lastname: Sánchez-Salado
authors.forename: S
authors.initials: S
authors.lastname: Ortega
authors.forename: E
authors.initials: E
authors.lastname: Oliver
authors.forename: N
authors.initials: N
authors.lastname: Manito
authors.forename: J
authors.initials: J
authors.lastname: Carratalà
mesh_terms: D000962:Antimalarials / Q000627:therapeutic use*; D037621:Artemisinins / Q000627:therapeutic use*; D000077332:Artesunate; D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D016778:Malaria, Falciparum / Q000188:drug therapy* / Q000635:transmission*; D008297:Male; D008875:Middle Aged; D010963:Plasmodium falciparum / Q000302:isolation & purification; D014019:Tissue Donors
chemical_list: D000962:Antimalarials; D037621:Artemisinins; D000077332:Artesunate
keywords: artesunate; erythropheresis; heart transplant; severe malaria; solid organ transplantation