title: Transcription coactivator Arabidopsis ANGUSTIFOLIA3 modulates anthocyanin accumulation and light-induced root elongation through transrepression of Constitutive Photomorphogenic1.
abstract: ANGUSTIFOLIA3 (AN3), a transcription coactivator, is implicated in modulating cell proliferation. In this study, I found that AN3 is a novel regulator of anthocyanin biosynthesis and light-induced root elongation. Seedlings and seeds lacking AN3 activity presented significantly reduced anthocyanin accumulation and light-induced root elongation, whereas those of transgenic plants harbouring the 35S:AN3 construct exhibited increased anthocyanin accumulation. AN3 is required for the proper expression of other genes that affect anthocyanin accumulation and light-induced root elongation, Constitutive Photomorphogenic1 (COP1), encoding a RING motif - containing E3 ubiquitin ligase. AN3 was associated with COP1 promoter in vivo. Thus, AN3 may act with other proteins that bind to COP1 promoter to promote anthocyanin accumulation and inhibit light-induced root elongation.
authors.affiliation: School of Life Sciences, University of Science and Technology of China, Hefei, 230027, China.
authors.forename: Lai-Sheng
authors.initials: LS
authors.lastname: Meng
mesh_terms: D020816:Amino Acid Motifs; D000872:Anthocyanins / Q000378:metabolism*; D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development / Q000528:radiation effects; D029681:Arabidopsis Proteins / Q000235:genetics* / Q000378:metabolism; D018506:Gene Expression Regulation, Plant; D008027:Light; D018517:Plant Roots / Q000235:genetics / Q000254:growth & development / Q000528:radiation effects; D030821:Plants, Genetically Modified; D012097:Repressor Proteins / Q000235:genetics* / Q000378:metabolism; D036226:Seedlings / Q000235:genetics / Q000254:growth & development / Q000528:radiation effects; D015398:Signal Transduction / Q000502:physiology* / Q000528:radiation effects; D044767:Ubiquitin-Protein Ligases / Q000235:genetics* / Q000378:metabolism
chemical_list: D000872:Anthocyanins; D029681:Arabidopsis Proteins; D012097:Repressor Proteins; D044767:Ubiquitin-Protein Ligases; C452846:DETORQEO protein, Arabidopsis; C471983:AT2G32950 protein, Arabidopsis
keywords: light signalling; root growth