title: Tooth movement out of the bony wall using augmented corticotomy with nonautogenous graft materials for bone regeneration.
abstract: This prospective randomized split-mouth study was performed to compare the effects of augmented corticotomy with those of different nonautogenous bone graft materials combined with orthodontic tooth movement in dogs. Decortication was performed on the buccal bone surface of 6 male beagle dogs that were randomly assigned to receive grafts of deproteinized bovine bone mineral, irradiated cortical bone, or synthetic bone. Immediate orthodontic force was applied to the second and third premolars for buccal tipping for 6 weeks. The pocket depth and width of keratinized tissue (WKT) were measured. Histologic and histomorphometric analyses were performed. The probing depth, WKT, and ratio of the area of new bone to that of total bone on the buccal side were not significantly different between groups. All groups had considerable new bone formation on the pressure side. New bone formation on the buccal side and buccal plate formation in the coronal direction along the root surfaces were induced by the bone-derived and PDL-derived mesenchymal matrix, respectively. The angular change between groups was significantly different (P < 0.001). Augmented corticotomy using nonautogenous graft materials facilitated tooth movement without fenestrations and accelerated new bone formation on the pressure side.
authors.affiliation: Department of Orthodontics, School of Dentistry, Kyung Hee University, No.1 Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Republic of Korea.
authors.forename: Kye-Bok
authors.identifier: 0000-0002-2566-8264
authors.initials: KB
authors.lastname: Lee
authors.affiliation: Department of Oral and Maxillofacial Pathology and Research Center for Tooth & Periodontal Regeneration (MRC), School of Dentistry, Kyung Hee University, Seoul 130-701, Republic of Korea.
authors.forename: Dong-Yeol
authors.identifier: 0000-0001-7922-2754
authors.initials: DY
authors.lastname: Lee
authors.affiliation: Department of Orthodontics, School of Dentistry, Kyung Hee University, No.1 Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Republic of Korea.
authors.forename: Hyo-Won
authors.identifier: 0000-0002-4872-7095
authors.initials: HW
authors.lastname: Ahn
authors.affiliation: Department of Orthodontics, School of Dentistry, Kyung Hee University, No.1 Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Republic of Korea.
authors.forename: Seong-Hun
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Department of Oral and Maxillofacial Pathology and Research Center for Tooth & Periodontal Regeneration (MRC), School of Dentistry, Kyung Hee University, Seoul 130-701, Republic of Korea.
authors.forename: Eun-Cheol
authors.initials: EC
authors.lastname: Kim
authors.affiliation: Division of Periodontology, Department of Orofacial Science, University of California, San Francisco, CA 94122, USA.
authors.forename: Igor
authors.identifier: 0000-0001-5639-3956
authors.initials: I
authors.lastname: Roitman
mesh_terms: D000540:Alveolar Ridge Augmentation / Q000295:instrumentation / Q000379:methods*; D000818:Animals; D001641:Bicuspid / Q000473:pathology / Q000601:surgery*; D001861:Bone Regeneration / Q000502:physiology*; D016025:Bone Transplantation / Q000295:instrumentation / Q000379:methods*; D002130:Calcium Phosphates / Q000627:therapeutic use*; D004285:Dogs; D056948:Orthognathic Surgical Procedures / Q000295:instrumentation / Q000379:methods*; D014087:Tooth Movement Techniques / Q000295:instrumentation / Q000379:methods*; D014182:Transplantation, Autologous; D016896:Treatment Outcome
chemical_list: D002130:Calcium Phosphates; C485817:beta-tricalcium phosphate