title: Carotidynia after anticancer chemotherapy.
abstract: Carotidynia is characterised by inflammation limited to the common carotid artery, which has been recognised as a distinct disease entity by advanced vascular imaging. Although most cases of carotidynia are idiopathic, we herein present a case of carotidynia after anticancer chemotherapy. A 64-year-old male patient received docetaxel followed by granulocyte-colony stimulating factor (G-CSF) for the treatment of lung squamous carcinoma. After the treatment, bilateral cervical pain developed. Vascular imaging, including magnetic resonance imaging, computed tomography and ultrasonography, showed characteristics specific for carotidynia. Although there was no strong confirmation using tests such as a challenge test, our observations suggest that docetaxel or G-CSF could be a causative drug triggering carotidynia.
authors.affiliation: Division of Respiratory Medicine, Nihon University School of Medicine, 30-1 Ohyaguchikamimachi, Itabashi-ku, Tokyo 173-8610, Japan. shayashi@med.nihon-u.ac.jp.
authors.forename: Shinichi
authors.initials: S
authors.lastname: Hayashi
authors.forename: Shuichiro
authors.initials: S
authors.lastname: Maruoka
authors.forename: Noriaki
authors.initials: N
authors.lastname: Takahashi
authors.forename: Shu
authors.initials: S
authors.lastname: Hashimoto
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D017536:Carotid Artery, Common / Q000187:drug effects* / Q000473:pathology; D000077143:Docetaxel; D016179:Granulocyte Colony-Stimulating Factor / Q000009:adverse effects; D006801:Humans; D007249:Inflammation / Q000139:chemically induced*; D008175:Lung Neoplasms / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy; D043823:Taxoids / Q000009:adverse effects / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D000970:Antineoplastic Agents; D043823:Taxoids; D016179:Granulocyte Colony-Stimulating Factor; D000077143:Docetaxel