title: The extraordinary career of Professor Dr. Simon van Creveld.
abstract: Simon van Creveld received both the MD and PhD degrees and had a multifaceted medical and scientific education at many hospitals and research institutes in the Netherlands, Germany, and the UK. He and his wife were the first to develop insulin for the Netherlands. His major interests were in hemophilia and hemorrhagic disorders, which accounted for 87 of his publications. In 1934, van Creveld demonstrated that a dispersed protein fraction obtained from serum could reduce the clotting time of hemophilic blood. His interest in glycogen storage disease resulted in van Creveld-von Gierke disease for which van Creveld contributed four published articles. The Ellis-van Creveld syndrome, also known as chondroectodermal dysplasia, was published in 1940 and became well known to medical geneticists. During the Nazi occupation of the Netherlands, van Creveld's professorship was taken away from him because he was Jewish. His visits to hospitals of concentration camps to treat babies and give pediatric advice while wearing a Jewish Yellow Star and interacting with SS Commandants in charge, and then leaving can only be described as amazing. After the war, his professorship was returned, and in the same year as his retirement, he established a large Hemophila Treatment and Research Center now known as the Van Creveld Clinic, which celebrated its 40th anniversary in 2005.
authors.affiliation: Department of Oral & Maxillofacial Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
authors.forename: Paul J W
authors.initials: PJ
authors.lastname: Stoelinga
authors.forename: Walter E
authors.initials: WE
authors.lastname: Berdon
authors.forename: M Michael
authors.initials: MM
authors.lastname: Cohen
mesh_terms: D030342:Genetic Diseases, Inborn; D005858:Germany; D049672:History, 19th Century; D049673:History, 20th Century; D009426:Netherlands; D010372:Pediatrics
keywords: Acta Brevia Neerlandica; British Paediatric Association Meeting (1939); Camp Vught; Camp Westerbork; Ellis-van Creveld syndrome; Honorary Memberships; Jewish background; Liber Amicorum; Van Creveld Clinic; hemophilia; hemorrhagic disorders; insulin; van Creveld-von Gierke disease