title: [Prevalence of Streptococcus pneumoniae serotype 19A before and after the introduction of the heptavalent conjugate vaccine in Mexico].
abstract: OBJECTIVE
  To determine the prevalence of S. pneumoniae serotype 19A (Spn19A), before and after the introduction of heptavalent pneumococcal conjugate vaccine (PCV7) in Mexico.
  
  
  METHODS
  Descriptive study carried out in Mexico with surveillance information of pneumococcal disease, generated from the Sireva network. We performed lineal regression analysis with the proportion of Spn19A by year in two study periods. Data were analyzed using SPSS v.18 software.
  
  
  RESULTS
  A total of 1825 S. pneumoniae strains causing infection in pediatric population were recovered in the period 2000-2012, 225/12.3% were Spn19A, and of these, 75/6.3% were isolated in 2000-2008 and 150/23.6% in 2009-2012. There was an increase in antimicrobial resistance post-vaccination for all drugs except vancomycin.
  
  
  CONCLUSIONS
  It was observed that the frequency of this serotype and antimicrobial resistance increased after the introduction of PCV7.
authors.affiliation: Instituto Nacional de Salud Pública, Cuernavaca, México.
authors.forename: Gabriela
authors.initials: G
authors.lastname: Echániz-Avilés
authors.affiliation: Instituto Nacional de Salud Pública, Cuernavaca, México.
authors.forename: Lizbeth
authors.initials: L
authors.lastname: San Román-Álvarez
authors.affiliation: Instituto Nacional de Salud Pública, Cuernavaca, México.
authors.forename: Miguel
authors.initials: M
authors.lastname: Sánchez-Alemán
authors.affiliation: Instituto Nacional de Salud Pública, Cuernavaca, México.
authors.forename: María Noemí
authors.initials: MN
authors.lastname: Carnalla-Barajas
authors.affiliation: Instituto Nacional de Salud Pública, Cuernavaca, México.
authors.forename: Araceli
authors.initials: A
authors.lastname: Soto-Noguerón
mesh_terms: D002675:Child, Preschool; D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008800:Mexico; D008826:Microbial Sensitivity Tests; D011008:Pneumococcal Infections / Q000188:drug therapy / Q000517:prevention & control; D065288:Serogroup; D013296:Streptococcus pneumoniae / Q000145:classification* / Q000187:drug effects
chemical_list: D000069443:Heptavalent Pneumococcal Conjugate Vaccine