title: Stereopsis results at 4.5 years of age in the infant aphakia treatment study.
abstract: OBJECTIVE
  To determine whether stereopsis of infants treated for monocular cataracts varies with the type of optical correction used.
  
  
  METHODS
  Randomized prospective clinical trial.
  
  
  METHODS
  The Infant Aphakia Treatment Study randomized 114 patients with unilateral cataracts at age 1-7 months to either primary intraocular lens (IOL) or contact lens correction. At 4.5 years of age a masked examiner assessed stereopsis on these patients using 3 different tests: (1) Frisby; (2) Randot Preschool; and (3) Titmus Fly.
  
  
  RESULTS
  Twenty-eight patients (25%) had a positive response to at least 1 of the stereopsis tests. There was no statistically significant difference in stereopsis between the 2 treatment groups: Frisby (contact lens, 6 [11%]; IOL, 7 [13%]; P = .99), Randot (contact lens, 3 [6%]; IOL, 1 [2%]; P = .62), or Titmus (contact lens, 8 [15%]; IOL, 13 [23%]; P = .34). The median age at surgery for patients with stereopsis was younger than for those without stereopsis (1.2 vs 2.4 months; P = .002). The median visual acuity for patients with stereopsis was better than for those without stereopsis (20/40 vs 20/252; P = .0003).
  
  
  CONCLUSIONS
  The type of optical correction did not influence stereopsis outcomes. However, 2 other factors did: age at surgery and visual acuity in the treated eye at age 4.5 years. Early surgery for unilateral congenital cataract and the presence of visual acuity better than or equal to 20/40 appear to be more important than the type of initial optical correction used for the development of stereopsis.
authors.affiliation: Department of Vision Sciences, University of Alabama at Birmingham, Birmingham, Alabama.
authors.forename: E Eugenie
authors.initials: EE
authors.lastname: Hartmann
authors.affiliation: Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, Oregon.
authors.forename: Ann U
authors.initials: AU
authors.lastname: Stout
authors.affiliation: Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University School of Public Health, Atlanta, Georgia.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Lynn
authors.affiliation: Departments of Ophthalmology and Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas.
authors.forename: Kimberly G
authors.initials: KG
authors.lastname: Yen
authors.affiliation: Stacey Kruger MD and Associates, Miami, Florida.
authors.forename: Stacey J
authors.initials: SJ
authors.lastname: Kruger
authors.affiliation: Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia. Electronic address: scott.lambert@emory.edu.
authors.forename: Scott R
authors.initials: SR
authors.lastname: Lambert
mesh_terms: D001035:Aphakia / Q000503:physiopathology / Q000628:therapy*; D002675:Child, Preschool; D003261:Contact Lenses; D003867:Depth Perception / Q000502:physiology*; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D008297:Male; D015999:Multivariate Analysis; D011446:Prospective Studies; D014792:Visual Acuity / Q000502:physiology