title: Is axillary sonographic staging less accurate in invasive lobular breast cancer than in ductal breast cancer?
abstract: OBJECTIVE
  The purpose of this study was to determine whether axillary sonography is less accurate in invasive lobular breast cancer than in ductal breast cancer.
  
  
  METHODS
  Patients with invasive breast cancer were retrospectively identified from histologic records from 2010 to 2012. Staging axillary sonograms from 96 patients with primary breast cancer in each of 2 subgroups, invasive lobular carcinoma (ILC) and invasive ductal carcinoma (IDC), were reviewed. Preoperative sonographically guided 14-gauge core biopsy was performed on morphologically abnormal lymph nodes.
  
  
  RESULTS
  Thirty-one of 96 patients (32%) in each subgroup were node positive on final postoperative histopathologic analysis. Axillary staging sensitivity was 17 of 31 patients (54%) in the IDC subgroup and 15 of 31(48%) in the ILC subgroup. Further analysis of the data showed no statistically significant differences between these subgroups.
  
  
  CONCLUSIONS
  We found that there was no statistically significant difference in the accuracy of axillary sonographic staging between ILC and IDC.
authors.affiliation: Plymouth Hospitals NHS Trust and Peninsula Radiology Academy, Plymouth, England. psankaye@nhs.net.
authors.forename: Prashant
authors.initials: P
authors.lastname: Sankaye
authors.affiliation: Plymouth Hospitals NHS Trust and Peninsula Radiology Academy, Plymouth, England.
authors.forename: Sharmila
authors.initials: S
authors.lastname: Chhatani
authors.affiliation: Plymouth Hospitals NHS Trust and Peninsula Radiology Academy, Plymouth, England.
authors.forename: Gareth
authors.initials: G
authors.lastname: Porter
authors.affiliation: Plymouth Hospitals NHS Trust and Peninsula Radiology Academy, Plymouth, England.
authors.forename: Jim
authors.initials: J
authors.lastname: Steel
authors.affiliation: Plymouth Hospitals NHS Trust and Peninsula Radiology Academy, Plymouth, England.
authors.forename: Sarah
authors.initials: S
authors.lastname: Doyle
mesh_terms: D001365:Axilla / Q000000981:diagnostic imaging* / Q000473:pathology; D001706:Biopsy; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging* / Q000473:pathology; D018275:Carcinoma, Lobular / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging* / Q000473:pathology; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000000981:diagnostic imaging / Q000473:pathology; D009367:Neoplasm Staging; D012189:Retrospective Studies; D018084:Ultrasonography, Interventional
keywords: axillary sonography; breast cancer; breast ultrasound; invasive lobular breast cancer