title: Balloon-occluded transarterial chemoembolization using a 1.8-French tip coaxial microballoon catheter for hepatocellular carcinoma: technical and safety considerations.
abstract: OBJECTIVE
  To evaluate the technical feasibility and safety considerations of balloon-occluded transarterial chemoembolization (B-TACE) using a newly developed 1.8-French (Fr) tip microballoon catheter for hepatocellular carcinoma (HCC).
  
  
  METHODS
  Between February 2013 and May 2013, 31 patients (20 males, 11 females; age range 56-85 years) underwent B-TACE using a 1.8-Fr tip microballoon catheter for unresectable HCC. The technical success rate, procedural complications, and adverse events of B-TACE were retrospectively investigated.
  
  
  RESULTS
  A total of 31 patients were subjected to 70 sessions of B-TACE using a 1.8-Fr tip microballoon catheter. The level of B-TACE was sub-subsegmental in 11, subsegmental in 35, segmental in 14, lobar in five, and right inferior phrenic artery in five sessions. The overall technical success rate was 99% (69 out of 70 sessions). As procedural complications, rupturing of the microballoon (n = 3) and aneurysmal dilatation at the site of balloon occlusion (n = 2) were encountered. There were no significant differences in any parameters between blood biochemical examination before and between two to four weeks after the procedure.
  
  
  CONCLUSIONS
  A 1.8-Fr tip microballoon catheter enables selective catheterization in patients with HCC and B-TACE using the 1.8-Fr tip microballoon catheter is a safe procedure.
authors.affiliation: Department of Radiology, Tokai University Hachioji Hospital, Tokai University School of Medicine , Tokyo , Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Jun
authors.initials: J
authors.lastname: Endo
authors.forename: Kazunobu
authors.initials: K
authors.lastname: Hashida
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Ichikawa
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Kojima
authors.forename: Shinji
authors.initials: S
authors.lastname: Takashimizu
authors.forename: Norihito
authors.initials: N
authors.lastname: Watanabe
authors.forename: Takuji
authors.initials: T
authors.lastname: Yamagami
authors.forename: Terumitsu
authors.initials: T
authors.lastname: Hasebe
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D021721:Balloon Occlusion / Q000295:instrumentation*; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D002404:Catheterization / Q000295:instrumentation; D016461:Chemoembolization, Therapeutic / Q000295:instrumentation* / Q000379:methods*; D002945:Cisplatin / Q000008:administration & dosage; D004998:Ethiodized Oil / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D012189:Retrospective Studies
chemical_list: D000970:Antineoplastic Agents; D009944:Organoplatinum Compounds; C406530:miriplatin; D004998:Ethiodized Oil; D002945:Cisplatin
keywords: Interventional radiology; balloon-occluded transarterial chemoembolization; catheter interventions; hepatocellular carcinoma; microballoon catheter; minimally invasive procedures