title: Sesavirus: prototype of a new parvovirus genus in feces of a sea lion.
abstract: We describe the nearly complete genome of a highly divergent parvovirus, we tentatively name Sesavirus, from the feces of a California sea lion pup (Zalophus californianus) suffering from malnutrition and pneumonia. The 5,049-base-long genome contained two major ORFs encoding a 553-aa nonstructural protein and a 965-aa structural protein which shared closest amino acid identities of 25 and 28 %, respectively, with members of the copiparvovirus genus known to infect pigs and cows. Given the low degree of similarity, Sesavirus might be considered as prototype for a new genus with a proposed name of Marinoparvovirus in the subfamily Parvovirinae.
authors.affiliation: Blood Systems Research Institute, San Francisco, CA, 94118, USA.
authors.forename: Tung Gia
authors.initials: TG
authors.lastname: Phan
authors.forename: Frances
authors.initials: F
authors.lastname: Gulland
authors.forename: Claire
authors.initials: C
authors.lastname: Simeone
authors.forename: Xutao
authors.initials: X
authors.lastname: Deng
authors.forename: Eric
authors.initials: E
authors.lastname: Delwart
mesh_terms: D000818:Animals; D002140:California; D004267:DNA Viruses / Q000235:genetics* / Q000302:isolation & purification; D004279:DNA, Viral / Q000737:chemistry* / Q000235:genetics*; D005243:Feces / Q000821:virology; D016679:Genome, Viral; D044342:Malnutrition / Q000662:veterinary; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D017992:Parvovirus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D011024:Pneumonia, Viral / Q000662:veterinary; D046070:Sea Lions / Q000821:virology*; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid
chemical_list: D004279:DNA, Viral