title: The effects of liraglutide on male fertility: a case report.
abstract: Liraglutide is an agonist of the glucagon-like peptide I receptor, and is commonly recommended as a treatment for obesity and type 2 diabetes mellitus. Adverse effects related to liraglutide include acute pancreatitis and polyarthritis. No studies, however, have reported an adverse effect of liraglutide on male reproduction. This case report shows a deleterious effect of liraglutide on male reproductive function.
authors.affiliation: Department of Anatomy, State University of Rio de Janeiro, Rio de Janeiro 20551-030, Brazil.
authors.forename: Paula
authors.initials: P
authors.lastname: Fontoura
authors.affiliation: Vida Centro de Fertilidade Clinic, Rio de Janeiro, Rio de Janeiro 22793-080, Brazil.
authors.forename: Maria Cecilia de Almeida
authors.initials: MC
authors.lastname: Cardoso
authors.affiliation: Vida Centro de Fertilidade Clinic, Rio de Janeiro, Rio de Janeiro 22793-080, Brazil.
authors.forename: Maria Cecilia
authors.initials: MC
authors.lastname: Erthal-Martins
authors.affiliation: Vida Centro de Fertilidade Clinic, Rio de Janeiro, Rio de Janeiro 22793-080, Brazil.
authors.forename: Caio
authors.initials: C
authors.lastname: Werneck
authors.affiliation: Vida Centro de Fertilidade Clinic, Rio de Janeiro, Rio de Janeiro 22793-080, Brazil.
authors.forename: Cassio
authors.initials: C
authors.lastname: Sartorio
authors.affiliation: Department of Anatomy, State University of Rio de Janeiro, Rio de Janeiro 20551-030, Brazil. Electronic address: cristiane@pesquisador.cnpq.br.
authors.forename: Cristiane Fonte
authors.initials: CF
authors.lastname: Ramos
mesh_terms: D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy; D005260:Female; D005298:Fertility / Q000187:drug effects*; D052216:Glucagon-Like Peptide 1 / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects*; D007248:Infertility, Male / Q000139:chemically induced*; D000069450:Liraglutide; D008297:Male; D009765:Obesity / Q000150:complications / Q000188:drug therapy; D011247:Pregnancy; D011256:Pregnancy Outcome; D013076:Sperm Count; D020554:Sperm Injections, Intracytoplasmic; D013081:Sperm Motility / Q000187:drug effects; D013094:Spermatozoa / Q000187:drug effects
chemical_list: D007004:Hypoglycemic Agents; D000069450:Liraglutide; D052216:Glucagon-Like Peptide 1
keywords: liraglutide; male infertility; male reproduction; spermatozoa