title: PFP/ESG: automated protein function prediction servers enhanced with Gene Ontology visualization tool.
abstract: Protein function prediction (PFP) is an automated function prediction method that predicts Gene Ontology (GO) annotations for a protein sequence using distantly related sequences and contextual associations of GO terms. Extended similarity group (ESG) is another GO prediction algorithm that makes predictions based on iterative sequence database searches. Here, we provide interactive web servers for the PFP and ESG algorithms that are equipped with an effective visualization of the GO predictions in a hierarchical topology.
  
  
  BACKGROUND
  PFP/ESG servers are freely available at http://kiharalab.org/web/pfp.php and http://kiharalab.org/web/esg.php, or access both at http://kiharalab.org/pfp_esg.php.
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors.affiliation: Department of Computer Science and Department of Biological Science, Purdue University, West Lafayette, IN 47907, USA.
authors.forename: Ishita K
authors.initials: IK
authors.lastname: Khan
authors.affiliation: Department of Computer Science and Department of Biological Science, Purdue University, West Lafayette, IN 47907, USA.
authors.forename: Qing
authors.initials: Q
authors.lastname: Wei
authors.affiliation: Department of Computer Science and Department of Biological Science, Purdue University, West Lafayette, IN 47907, USA.
authors.forename: Meghana
authors.initials: M
authors.lastname: Chitale
authors.affiliation: Department of Computer Science and Department of Biological Science, Purdue University, West Lafayette, IN 47907, USA Department of Computer Science and Department of Biological Science, Purdue University, West Lafayette, IN 47907, USA.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Kihara
mesh_terms: D000465:Algorithms; D019295:Computational Biology / Q000379:methods*; D003196:Computer Graphics; D030562:Databases, Protein; D063990:Gene Ontology; D006801:Humans; D058977:Molecular Sequence Annotation; D011506:Proteins / Q000378:metabolism*; D020539:Sequence Analysis, Protein / Q000379:methods*
chemical_list: D011506:Proteins