title: [A rare case of thalassemia concomitant with chronic decompensated tonsillitis].
abstract: The present paper reports a rare combination of Cooley's disease (thalassemia B) and the decompensated variant of chronic tonsillitis in a 14-year old girl. The patient presented with the severe form of hypochromic anemia and degenerative changes of erythrocytes. She was treated by means of bilateral tonsillectomy associated with the high risk of postoperative hemorrhage. In the preoperative period, the child received drop intravenous infusion of tranexam at a dose of 15 mg/kg body weight together with hemostatic agents. Hemorrhage during the surgical intervention was stopped by pressing tampons impregnated with tranexamic acid known to exert local and systemic hemostatic and antifibrinolytic action. The patient was discharged from the hospital for the further treatment of the primary disease.
authors.forename: A I
authors.initials: AI
authors.lastname: Izvin
authors.forename: N E
authors.initials: NE
authors.lastname: Kuznetsova
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Siniakov
mesh_terms: D000293:Adolescent; D000747:Anemia, Hypochromic / Q000209:etiology* / Q000503:physiopathology; D000933:Antifibrinolytic Agents / Q000627:therapeutic use; D018890:Chemoprevention / Q000379:methods; D002908:Chronic Disease; D005260:Female; D006489:Hemostatic Techniques; D006801:Humans; D019106:Postoperative Hemorrhage / Q000517:prevention & control; D020379:Risk Adjustment; D013789:Thalassemia / Q000150:complications / Q000503:physiopathology; D014068:Tonsillectomy / Q000009:adverse effects / Q000379:methods; D014069:Tonsillitis / Q000150:complications / Q000503:physiopathology / Q000601:surgery; D014148:Tranexamic Acid / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000933:Antifibrinolytic Agents; D014148:Tranexamic Acid