title: Asymmetric total synthesis of novel pentacyclic indole alkaloid, kopsiyunnanine E, isolated from Kopsia arborea.
abstract: A new pentacyclic indole alkaloid, kopsiyunnanine E, was isolated from Yunnan Kopsia arborea, and its structure, which was inferred from spectroscopic data, was established by a 16-step asymmetric total synthesis that proved that the natural alkaloid was not enantiomerically pure.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Chiba University , 1-8-1 Inohana, Chuo-ku, Chiba 260-8675, Japan.
authors.forename: Mariko
authors.initials: M
authors.lastname: Kitajima
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Murakami
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Takahashi
authors.forename: Yuqiu
authors.initials: Y
authors.lastname: Wu
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Kogure
authors.forename: Rong-Ping
authors.initials: RP
authors.lastname: Zhang
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Takayama
mesh_terms: D029062:Apocynaceae / Q000737:chemistry*; D002681:China; D026121:Indole Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013237:Stereoisomerism
chemical_list: D026121:Indole Alkaloids; C000593341:kopsiyunnanine E