title: Pulmonary hypertension and its management in patients undergoing non-cardiac surgery.
abstract: Pulmonary hypertension is a complex disorder of the pulmonary vasculature that leads to increased peri-operative morbidity and mortality. Non-cardiac surgery constitutes a significant risk in patients with pulmonary hypertension. The management of right ventricular failure is inherently challenging and fraught with life-threatening consequences. A thorough understanding of the pathophysiology, the severity of the disease and its treatment modalities is required to deliver optimal peri-operative care. This review provides an evidence-based overview of the definition, classification, pathophysiology, diagnosis and treatment of pulmonary hypertension and focuses on the peri-operative management and treatment of pulmonary hypertensive crises in a non-cardiac setting.
authors.affiliation: Department of Anaesthesia, The Queen Elizabeth Hospital NHS Foundation Trust, King's Lynn, UK.
authors.forename: S A
authors.initials: SA
authors.lastname: Pilkington
authors.forename: D
authors.initials: D
authors.lastname: Taboada
authors.forename: G
authors.initials: G
authors.lastname: Martinez
mesh_terms: D000768:Anesthesia, General / Q000379:methods; D000959:Antihypertensive Agents / Q000627:therapeutic use; D006348:Cardiac Surgical Procedures; D019317:Evidence-Based Medicine / Q000379:methods; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D019990:Perioperative Care / Q000379:methods*; D018570:Risk Assessment / Q000379:methods; D013514:Surgical Procedures, Operative; D009626:Terminology as Topic
chemical_list: D000959:Antihypertensive Agents