title: Multicomponent decarboxylative allylations.
abstract: The reaction of Meldrum's acid, pyrrolide, and allyl carbonates allows a multicomponent decarboxylative coupling to form allylated acyl pyrroles. This strategy is made possible by the in situ formation of β-oxo carboxylates from Meldrum's acid. Subsequent decarboxylative enolate formation and electrophilic allylation complete the reaction. Addition of benzylidene malononitriles as good Michael acceptors allow a 4-component interceptive decarboxylative allylation.
authors.affiliation: The University of Kansas Department of Chemistry, 2010 Malott Hall, 1251 Wescoe Hall Dr., Lawrence, KS 66045, USA. tunge@ku.edu.
authors.forename: Yamuna
authors.initials: Y
authors.lastname: Ariyarathna
authors.forename: Jon A
authors.initials: JA
authors.lastname: Tunge