title: Anticancer effects of different seaweeds on human colon and breast cancers.
abstract: Seafoods and seaweeds represent some of the most important reservoirs of new therapeutic compounds for humans. Seaweed has been shown to have several biological activities, including anticancer activity. This review focuses on colorectal and breast cancers, which are major causes of cancer-related mortality in men and women. It also describes various compounds extracted from a range of seaweeds that have been shown to eradicate or slow the progression of cancer. Fucoidan extracted from the brown algae Fucus spp. has shown activity against both colorectal and breast cancers. Furthermore, we review the mechanisms through which these compounds can induce apoptosis in vitro and in vivo. By considering the ability of compounds present in seaweeds to act against colorectal and breast cancers, this review highlights the potential use of seaweeds as anticancer agents.
authors.affiliation: Department of Biological Science, College of Natural Science, Wonkwang University, Iksan, Jeonbuk 570-749, Korea. strozzi37@gmail.com.
authors.forename: Ghislain
authors.initials: G
authors.lastname: Moussavou
authors.affiliation: Department of Biological Science, College of Natural Science, Wonkwang University, Iksan, Jeonbuk 570-749, Korea. velvety7@gmail.com.
authors.forename: Dong Hoon
authors.initials: DH
authors.lastname: Kwak
authors.affiliation: Department of Food Science and Nutrition, Keimyung University, Daegu 704-701, Korea. obiang@gw.kmu.ac.kr.
authors.forename: Brice Wilfried
authors.initials: BW
authors.lastname: Obiang-Obonou
authors.affiliation: Department of Biological Science, College of Natural Science, Wonkwang University, Iksan, Jeonbuk 570-749, Korea. cyrabel@hotmail.com.
authors.forename: Cyr Abel Ogandaga
authors.initials: CA
authors.lastname: Maranguy
authors.affiliation: Department of Parasitology and Tropical Medicine, Kyungpook National University, Daegu 700-422, Korea. sylvatriez@yahoo.fr.
authors.forename: Sylvatrie-Danne
authors.initials: SD
authors.lastname: Dinzouna-Boutamba
authors.affiliation: Department of Biological Science, College of Natural Science, Wonkwang University, Iksan, Jeonbuk 570-749, Korea. dleogns@korea.kr.
authors.forename: Dae Hoon
authors.initials: DH
authors.lastname: Lee
authors.affiliation: Department of Civil and Environmental Engineering, Kookmin University, Seoul 136-702, Korea. deliapish@gmail.com.
authors.forename: Ordelia Gwenaelle Manvoudou
authors.initials: OG
authors.lastname: Pissibanganga
authors.affiliation: Department of Medicine, College of Medicine, Chung-Ang University, Seoul 156-756, Korea. ksko@cau.ac.kr.
authors.forename: Kisung
authors.initials: K
authors.lastname: Ko
authors.affiliation: College of Pharmacy, Yonsei University, Veritas D, Yonsei International Campus, Songdo-dong, Yeonsu-gu, Incheon 406-840, Korea. kakijane@yonsei.ac.kr.
authors.forename: Jae In
authors.initials: JI
authors.lastname: Seo
authors.affiliation: Department of Biological Science, College of Natural Science, Wonkwang University, Iksan, Jeonbuk 570-749, Korea. ykchoo@wku.ac.kr.
authors.forename: Young Kug
authors.initials: YK
authors.lastname: Choo
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology*; D001943:Breast Neoplasms / Q000188:drug therapy*; D003110:Colonic Neoplasms / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D012624:Seaweed / Q000737:chemistry*
chemical_list: D000970:Antineoplastic Agents