title: [Research of bimingan granule on dendritic cell in allergic rhinitis mice].
abstract: OBJECTIVE
  To investigate the mechanism.
  
  
  METHODS
  We isolate the mouse bone marrow cells and cultured with rGM-CSF and rIL-4 to stimulate bone marrow cells to transfer to immature dendritic cells. And then the immature dendritic cells were costimulated with ILPS and different concentrations of Bimingan Granule.
  
  
  RESULTS
  MHC II, CD80, CD86 were detected by flow cytometer and TNF-alpha, IL-1beta, IL-6 and IL-10 were quantified by ELISA.
  
  
  CONCLUSIONS
  Our results showed that Bimingan Granule may significantly inhibit the differentiation of immature dendritic cells to mature dendritic cells.
authors.forename: Jiyong
authors.initials: J
authors.lastname: Wu
authors.forename: Daonan
authors.initials: D
authors.lastname: Yan
authors.forename: Hua'an
authors.initials: H
authors.lastname: Ma
authors.forename: Yun
authors.initials: Y
authors.lastname: Zhu
authors.forename: Shizhong
authors.initials: S
authors.lastname: Zhang
authors.forename: Yao
authors.initials: Y
authors.lastname: Hu
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects; D002478:Cells, Cultured; D003713:Dendritic Cells / Q000187:drug effects / Q000276:immunology*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D051379:Mice; D008810:Mice, Inbred C57BL; D065631:Rhinitis, Allergic / Q000188:drug therapy / Q000276:immunology*
chemical_list: D004365:Drugs, Chinese Herbal