title: Low-magnitude high-frequency loading, by whole-body vibration, accelerates early implant osseointegration in ovariectomized rats.
abstract: Osteoporosis deteriorates jaw bone quality and may compromise early implant osseointegration and early implant loading. The influence of low‑magnitude, high‑frequency (LMHF) vibration on peri‑implant bone healing and implant integration in osteoporotic bones remains poorly understood. LMHF loading via whole‑body vibration (WBV) for 8 weeks has previously been demonstrated to significantly enhance bone‑to‑implant contact, peri‑implant bone fraction and implant mechanical properties in osteoporotic rats. In the present study, LMHF loading by WBV was performed in osteoporotic rats, with a loading duration of 4 weeks during the early stages of bone healing. The results indicated that 4‑week LMHF loading by WBV partly reversed the negative effects of osteoporosis and accelerated early peri‑implant osseointegration in ovariectomized rats.
authors.affiliation: Department of Stomatology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
authors.forename: Yong-Qiang
authors.initials: YQ
authors.lastname: Liang
authors.affiliation: College of Stomatology, Hebei United University, Tangshan, Hebei 063000, P.R. China.
authors.forename: Meng-Chun
authors.initials: MC
authors.lastname: Qi
authors.affiliation: Department of Stomatology, Tongchuan City People's Hospital, Tongchuan, Shaanxi 727100, P.R. China.
authors.forename: Jiang
authors.initials: J
authors.lastname: Xu
authors.affiliation: Department of Stomatology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
authors.forename: Juan
authors.initials: J
authors.lastname: Xu
authors.affiliation: Department of Stomatology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
authors.forename: Hua-Wei
authors.initials: HW
authors.lastname: Liu
authors.affiliation: College of Stomatology, Hebei United University, Tangshan, Hebei 063000, P.R. China.
authors.forename: Wei
authors.initials: W
authors.lastname: Dong
authors.affiliation: College of Stomatology, Hebei United University, Tangshan, Hebei 063000, P.R. China.
authors.forename: Jin-Yuan
authors.initials: JY
authors.lastname: Li
authors.affiliation: Department of Stomatology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
authors.forename: Min
authors.initials: M
authors.lastname: Hu
mesh_terms: D000818:Animals; D015519:Bone Density / Q000187:drug effects; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D005260:Female; D016348:Osseointegration / Q000187:drug effects*; D010012:Osteogenesis / Q000187:drug effects; D010024:Osteoporosis / Q000188:drug therapy; D010052:Ovariectomy / Q000379:methods; D019736:Prostheses and Implants; D051381:Rats; D017207:Rats, Sprague-Dawley; D013977:Tibia / Q000187:drug effects; D014025:Titanium / Q000494:pharmacology; D014732:Vibration / Q000627:therapeutic use*
chemical_list: D050071:Bone Density Conservation Agents; D014025:Titanium