title: Electrochemically initiated oxidative amination of benzoxazoles using tetraalkylammonium halides as redox catalysts.
abstract: An electrochemically promoted coupling of benzoxazoles and amines has been developed, leading directly to the formation of 2-aminobenzoxazoles. The chemistry utilizes catalytic quantities of a tetraalkylammonium halide redox catalyst and is carried out under constant current conditions in a simple undivided cell. The use of excess chemical oxidant or large amounts of supporting electrolyte is avoided. This greatly simplifies the workup and isolation process and leads to a reduction in waste.
authors.affiliation: College of Life Science & Bioengineering, Beijing University of Technology , Beijing 100124, China.
authors.forename: Wei-Jing
authors.initials: WJ
authors.lastname: Gao
authors.forename: Wei-Cui
authors.initials: WC
authors.lastname: Li
authors.forename: Cheng-Chu
authors.initials: CC
authors.lastname: Zeng
authors.forename: Hong-Yu
authors.initials: HY
authors.lastname: Tian
authors.forename: Li-Ming
authors.initials: LM
authors.lastname: Hu
authors.forename: R Daniel
authors.initials: RD
authors.lastname: Little
mesh_terms: D000586:Amination; D001583:Benzoxazoles / Q000737:chemistry*; D002384:Catalysis; D006219:Halogens / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*
chemical_list: D001583:Benzoxazoles; D006219:Halogens; D000644:Quaternary Ammonium Compounds