title: Longitudinal Trends in Sexual Behaviors with Advancing Age and Menopause Among Women With and Without HIV-1 Infection.
abstract: We assessed changes in self-reported sexual activity (SA) over 13 years among HIV-infected and uninfected women. The impact of aging and menopause on SA and unprotected anal or vaginal intercourse (UAVI) was examined among women in the Women's Interagency HIV Study (WIHS), stratifying by HIV status and detectable viral load among HIV-infected women. Generalized mixed linear models were fitted for each outcome, adjusted for relevant covariates. HIV-uninfected women evidenced higher levels of SA and UAVI than HIV-infected. The odds of SA declined by 62-64 % per decade of age. The odds of SA in a 6-month interval for women aged 40-57 declined by 18-22 % post-menopause (controlling for age). Among HIV+/detectable women only, the odds of any UAVI decreased by 17 % per decade of age; the odds of UAVI were unchanged pre-menopause, and then decreased by 28 % post-menopause. Elucidating the factors accounting for ongoing unprotected sex among older women should inform interventions.
authors.affiliation: Special Treatment and Research Program, SUNY Downstate Medical Center, Brooklyn, NY, USA, Tonya.Taylor@downstate.edu.
authors.forename: Tonya N
authors.initials: TN
authors.lastname: Taylor
authors.forename: Jeremy
authors.initials: J
authors.lastname: Weedon
authors.forename: Elizabeth T
authors.initials: ET
authors.lastname: Golub
authors.forename: Stephen E
authors.initials: SE
authors.lastname: Karpiak
authors.forename: Monica
authors.initials: M
authors.lastname: Gandhi
authors.forename: Mardge H
authors.initials: MH
authors.lastname: Cohen
authors.forename: Alexandra M
authors.initials: AM
authors.lastname: Levine
authors.forename: Howard L
authors.initials: HL
authors.lastname: Minkoff
authors.forename: Adebola A
authors.initials: AA
authors.lastname: Adedimeji
authors.forename: Lakshmi
authors.initials: L
authors.lastname: Goparaju
authors.forename: Susan
authors.initials: S
authors.lastname: Holman
authors.forename: Tracey E
authors.initials: TE
authors.lastname: Wilson
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D005260:Female; D015658:HIV Infections / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission; D006306:Health Surveys; D006801:Humans; D016015:Logistic Models; D008137:Longitudinal Studies; D008593:Menopause / Q000502:physiology*; D008875:Middle Aged; D011446:Prospective Studies; D012309:Risk-Taking; D012725:Sexual Behavior; D012747:Sexual Partners; D011795:Surveys and Questionnaires; D014481:United States / Q000453:epidemiology; D047568:Unsafe Sex / Q000706:statistics & numerical data*; D055815:Young Adult