title: Successful esophagectomy in a patient with combined esophageal cancer and hemophilia B.
abstract: Patients with esophageal cancer often require esophagectomy with esophagogastrostomy. However, the incidence of complications, such as hemorrhage, during operations for esophageal cancer is high, even with minimally invasive surgery. Without the appropriate interventions, the risk of major intraoperative and postoperative hemorrhage is very high in patients with esophageal cancer and hemophilia. We report the case of a 45-year-old man with esophageal cancer and hemophilia B who underwent a successful hybrid, minimally invasive Ivor-Lewis esophagectomy with appropriate perioperative management.
authors.affiliation: Guo-Fei Zhang, Ying Chai, Wen-Shan Li, Gang Shen, Department of Thoracic Surgery, the Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China.
authors.forename: Guo-Fei
authors.initials: GF
authors.lastname: Zhang
authors.affiliation: Guo-Fei Zhang, Ying Chai, Wen-Shan Li, Gang Shen, Department of Thoracic Surgery, the Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Chai
authors.affiliation: Guo-Fei Zhang, Ying Chai, Wen-Shan Li, Gang Shen, Department of Thoracic Surgery, the Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China.
authors.forename: Wen-Shan
authors.initials: WS
authors.lastname: Li
authors.affiliation: Guo-Fei Zhang, Ying Chai, Wen-Shan Li, Gang Shen, Department of Thoracic Surgery, the Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China.
authors.forename: Lian-Sheng
authors.initials: LS
authors.lastname: Huang
authors.affiliation: Guo-Fei Zhang, Ying Chai, Wen-Shan Li, Gang Shen, Department of Thoracic Surgery, the Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Shen
mesh_terms: D001777:Blood Coagulation / Q000187:drug effects*; D001779:Blood Coagulation Factors / Q000008:administration & dosage* / Q000009:adverse effects; D001780:Blood Coagulation Tests; D016063:Blood Loss, Surgical / Q000517:prevention & control; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D004334:Drug Administration Schedule; D004938:Esophageal Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D000077277:Esophageal Squamous Cell Carcinoma; D016629:Esophagectomy / Q000009:adverse effects; D006397:Hematinics / Q000008:administration & dosage* / Q000009:adverse effects; D002836:Hemophilia B / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D061646:Operative Time; D019990:Perioperative Care; D019106:Postoperative Hemorrhage / Q000517:prevention & control; D018714:Radiotherapy, Adjuvant; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D001779:Blood Coagulation Factors; D006397:Hematinics; C025667:prothrombin complex concentrates
keywords: Esophageal cancer; Esophagectomy; Esophagogastrostomy; Hemophilia B; Hemorrhage