title: PINBPA: cytoscape app for network analysis of GWAS data.
abstract: Protein interaction network-based pathway analysis (PINBPA) for genome-wide association studies (GWAS) has been developed as a Cytoscape app, to enable analysis of GWAS data in a network fashion. Users can easily import GWAS summary-level data, draw Manhattan plots, define blocks, prioritize genes with random walk with restart, detect enriched subnetworks and test the significance of subnetworks via a user-friendly interface.
  
  
  METHODS
  PINBPA app is freely available in Cytoscape app store.
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors.affiliation: School of Computing, Queen's University, 25 Union Street, Goodwin Hall, Kingston, Ontario K7L 3N6, Canada and Department of Neurology, University of California San Francisco, 675 Nelson Rising Lane, Room 215, San Francisco, CA 94158, USA.
authors.forename: Lili
authors.initials: L
authors.lastname: Wang
authors.affiliation: School of Computing, Queen's University, 25 Union Street, Goodwin Hall, Kingston, Ontario K7L 3N6, Canada and Department of Neurology, University of California San Francisco, 675 Nelson Rising Lane, Room 215, San Francisco, CA 94158, USA.
authors.forename: Takuya
authors.initials: T
authors.lastname: Matsushita
authors.affiliation: School of Computing, Queen's University, 25 Union Street, Goodwin Hall, Kingston, Ontario K7L 3N6, Canada and Department of Neurology, University of California San Francisco, 675 Nelson Rising Lane, Room 215, San Francisco, CA 94158, USA.
authors.forename: Lohith
authors.initials: L
authors.lastname: Madireddy
authors.affiliation: School of Computing, Queen's University, 25 Union Street, Goodwin Hall, Kingston, Ontario K7L 3N6, Canada and Department of Neurology, University of California San Francisco, 675 Nelson Rising Lane, Room 215, San Francisco, CA 94158, USA.
authors.forename: Parvin
authors.initials: P
authors.lastname: Mousavi
authors.affiliation: School of Computing, Queen's University, 25 Union Street, Goodwin Hall, Kingston, Ontario K7L 3N6, Canada and Department of Neurology, University of California San Francisco, 675 Nelson Rising Lane, Room 215, San Francisco, CA 94158, USA.
authors.forename: Sergio E
authors.initials: SE
authors.lastname: Baranzini
mesh_terms: D000465:Algorithms; D057225:Data Mining / Q000379:methods*; D055106:Genome-Wide Association Study; D006801:Humans; D060066:Protein Interaction Maps; D040901:Proteomics; D012984:Software