title: [The lack of adherence to antiosteoporotic drugs: crossing methods, the key to adherence measurement?].
abstract: OBJECTIVE
  To use two different techniques to assess adherence of patients treated with antiosteoporotic drug.
  
  
  METHODS
  This monocentric transversal study was performed on a 6 months period, on patients of a single French pharmacy treated with antiosteoporotic drugs. Adherence was assessed crossing 2 techniques (patient autoquestionnaire and medication possession ratio measurement). Statistical analysis consisted in a description of the population study and a multivariate logistic regression to identify the factors associated with a lack of observance.
  
  
  RESULTS
  Using the two techniques, the lack of adherence was estimated to be between 14 and 55%. Adherence was better in patients who were given dietetic advice or information about the usefulness of physical activity and worse in patients who reached menopause less than 23 years ago.
  
  
  CONCLUSIONS
  A better identification of patients with a lack of observance is possible by crossing several techniques to assess adherence of the patient to his antiosteoporotic drug.
authors.affiliation: Laboratoire de Pharmacologie médicale et clinique, Faculté de Médecine de l'Université de Toulouse III Paul Sabatier, Toulouse, France - Service de Pharmacologie médicale et clinique, Centre Midi-Pyrénées de Pharmacovigilance, de Pharmacoépidémiologie et d'Informations sur le Médicament, Centre hospitalier universitaire de Toulouse, Toulouse, France - Équipe de Pharmacoépidémiologie de l'UMR INSERM 1027, Faculté de Médecine de l'Université de Toulouse, Toulouse, France.
authors.forename: Layla
authors.initials: L
authors.lastname: Saliba
authors.affiliation: Laboratoire de Pharmacie clinique, Faculté de Pharmacie, Toulouse, France.
authors.forename: Laura
authors.initials: L
authors.lastname: Boisson
authors.affiliation: Laboratoire de Pharmacie clinique, Faculté de Pharmacie, Toulouse, France - Service de la Pharmacie à usage intérieur, Centre hospitalier universitaire de Toulouse, Toulouse, France.
authors.forename: Brigitte
authors.initials: B
authors.lastname: Sallerin
authors.affiliation: Service de Rhumatologie, Centre hospitalier universitaire de Toulouse, Toulouse, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Laroche
authors.affiliation: Laboratoire de Pharmacologie médicale et clinique, Faculté de Médecine de l'Université de Toulouse III Paul Sabatier, Toulouse, France - Service de Pharmacologie médicale et clinique, Centre Midi-Pyrénées de Pharmacovigilance, de Pharmacoépidémiologie et d'Informations sur le Médicament, Centre hospitalier universitaire de Toulouse, Toulouse, France - Équipe de Pharmacoépidémiologie de l'UMR INSERM 1027, Faculté de Médecine de l'Université de Toulouse, Toulouse, France.
authors.forename: Fabien
authors.initials: F
authors.lastname: Despas
mesh_terms: D000368:Aged; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D015340:Epidemiologic Research Design; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000188:drug therapy* / Q000453:epidemiology*; D016903:Drug Monitoring
chemical_list: D050071:Bone Density Conservation Agents