title: Hepatic portal venous gas in Crohn's disease.
abstract: Hepatic portal venous gas (HPVG) is a rare finding that has only been reported previously among 25 patients with Crohn's disease in the English literature. We present a case of a 27-year-old woman with Crohn's disease who presented with fever, abdominal pain and per rectal bleeding and was found to have HPVG at the time of presentation most likely due to an enterovenous fistula. She was managed with intravenous antibiotics, corticosteroids and infliximab and subsequently made a full recovery. HPVG is most likely a manifestation of penetrating Crohn's disease, is overall associated with a low mortality rate and can be managed conservatively in the majority of cases associated with Crohn's disease. Although surgery has been suggested for cases of enterovenous fistulae in the past, this is the first case to suggest that use of antitumour necrosis factor therapy may arrest associated gastrointestinal bleeding and avoid the need for surgery.
authors.affiliation: Department of Gastroenterology, St Vincent's Hospital, Melbourne, Victoria, Australia.
authors.forename: Georgina
authors.initials: G
authors.lastname: Cunningham
authors.affiliation: Department of Gastroenterology, St Vincent's Hospital, Melbourne, Victoria, Australia.
authors.forename: Georgina
authors.initials: G
authors.lastname: Cameron
authors.affiliation: Department of Gastroenterology, St Vincent's Hospital, Melbourne, Victoria, Australia. Department of Gastroenterology, Austin Health, Melbourne, Victoria, Australia Department of Medicine, The University of Melbourne, Austin Academic Center, Melbourne, Victoria, Australia.
authors.forename: Peter
authors.initials: P
authors.lastname: De Cruz
mesh_terms: D000328:Adult; D003424:Crohn Disease / Q000150:complications*; D005260:Female; D005740:Gases; D006801:Humans; D007412:Intestinal Fistula / Q000209:etiology*; D007421:Intestine, Small; D011169:Portal Vein; D016157:Vascular Fistula / Q000209:etiology*
chemical_list: D005740:Gases