title: [The influence of the single different radiation dose and time on the microscopic structure and ultrastructure of Balb/c mice].
abstract: OBJECTIVE
  To observe the influence of the single different radiation dose and time on the microscopic structure and ultrastructure of Balb/c Mice.
  
  
  METHODS
  Sixteen four-week-old mice were randomly divided into four groups, control group and three experimental groups, then every experimental group was randomly divided into two groups which were respectively sacrificed on the third and seventh day after exposure to different doses of 8, 12, 16 Gy radiation, then paraffin embedding, tissue section, HE staining and scanning electron microscope, observation were performed after a cochlear specimen collected.
  
  
  RESULTS
  Inner hair cells and outer hair cells arranged in order, no lodging, disorder or missing in control group under scanning electron microscope. Slight lodgy or disorder occured in inner cells and outer hair cells were missing sometimes in exposed animals,which meat irrespective of irradiation dose.
  
  
  CONCLUSIONS
  Slight changes of ultrastructure of Balb/c Mice occured in the early period when given eaqual to or less than 16 Gy radiation.
authors.forename: Chen
authors.initials: C
authors.lastname: Yang
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Xiaolong
authors.initials: X
authors.lastname: Liu
authors.forename: Yong
authors.initials: Y
authors.lastname: Liang
authors.forename: Peng
authors.initials: P
authors.lastname: Li
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yawei
authors.initials: Y
authors.lastname: Yuan
mesh_terms: D000818:Animals; D003051:Cochlea / Q000528:radiation effects / Q000648:ultrastructure*; D004307:Dose-Response Relationship, Radiation; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008855:Microscopy, Electron, Scanning; D011829:Radiation Dosage; D013997:Time Factors