title: RNA interference in the progress of gastric cancer.
abstract: Gastric cancer is one of common malignant tumors. The development of molecular biology and genetics prompts people to regulate tumor cell regulation from the gene level, and seeks method to the new tumor therapy. RNA interference (which is also called RNAi) is a technology of double stranded RNAexogenous or dsRNA into cells, therefore this thereby inhibits the expression function of corresponding target gene. This paper summarizes the development process and the mechanism of RNAi technology, outlines the progress of experimental gastric cancer of the current RNAi technology, which shows that this technology can directly or indirectly inhibit tumor, and reduce the drug resistance of tumor cells. With the gradual improvement of RNAi technology, it will become a new direction for gene therapy of gastric cancer.
authors.affiliation: General Internal Medicine, People's Hospital of Zhengzhou, China.
authors.forename: Lihua
authors.initials: L
authors.lastname: Wu
authors.affiliation: Tumor Surgery, People's Hospital of Zhengzhou, China.
authors.forename: Sisen
authors.initials: S
authors.lastname: Zhang
authors.affiliation: Emergency, People's Hospital of Zhengzhou, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Liu
authors.affiliation: Digestion Internal Medicine, People's Hospital of Zhengzhou, China.
authors.forename: Xiaoxin
authors.initials: X
authors.lastname: Shi
authors.affiliation: Tumor Surgery, People's Hospital of Zhengzhou, China.
authors.forename: Yingbin
authors.initials: Y
authors.lastname: Zheng
mesh_terms: D019008:Drug Resistance, Neoplasm; D015316:Genetic Therapy; D006801:Humans; D034622:RNA Interference; D013274:Stomach Neoplasms / Q000098:blood supply / Q000628:therapy*