title: Pediatric vs adult pulmonary tuberculosis: A retrospective computed tomography study.
abstract: OBJECTIVE
  To compare the manifestations of chest tuberculosis (TB) in pediatric and adult patients based on contrast enhanced computed tomography of chest.
  
  
  METHODS
  This was a retrospective study consisting of 152 patients of chest TB including 48 children and 104 adults who had undergone contrast enhanced computed tomography of chest prior to treatment. The patterns and severity of parenchymal, mediastinal and pleural manifestations were analyzed and compared among different age groups.
  
  
  RESULTS
  Parenchymal changes observed include consolidation, air space nodules, miliary TB, cavitation, bronchiectasis and fibrosis and these were noted in 60% of children, 71% of adolescents and 76.9% of adults. These changes were more common in right upper lobe in all age groups. There was no significant difference in the frequency of these changes (except nodules) in different age groups. Centrilobular nodules were seen less commonly in children less than 10 years (P = 0.028). Pleural effusion was noted in 28 (18.42%) patients and pericardial effusion in 8 (5.3%) patients. No significant difference in the serosal involvement is seen among children and adults. Mediastinal adenopathy was seen 70% of children, 76.3% adolescents and 76.9% of adults and paratracheal nodes were seen most frequently. Nodes had similar features (except matting) among all age groups. Matting of nodes was seen more commonly in children (P = 0.014).
  
  
  CONCLUSIONS
  Pediatric chest tuberculosis can have severe parenchymal lesions and nodal involvement similar to adults. The destructive lung changes observed in children needs immediate attention in view of the longer life span they have and hence in formulating optimal treatment strategies.
authors.affiliation: Prasad Thotton Veedu, Ashu Seith Bhalla, Arundeep Arora, Divya Singh, Arun Kumar Gupta, Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Prasad Thotton
authors.initials: PT
authors.lastname: Veedu
authors.affiliation: Prasad Thotton Veedu, Ashu Seith Bhalla, Arundeep Arora, Divya Singh, Arun Kumar Gupta, Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Ashu Seith
authors.initials: AS
authors.lastname: Bhalla
authors.affiliation: Prasad Thotton Veedu, Ashu Seith Bhalla, Arundeep Arora, Divya Singh, Arun Kumar Gupta, Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Sreenivas
authors.initials: S
authors.lastname: Vishnubhatla
authors.affiliation: Prasad Thotton Veedu, Ashu Seith Bhalla, Arundeep Arora, Divya Singh, Arun Kumar Gupta, Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Sushil Kumar
authors.initials: SK
authors.lastname: Kabra
authors.affiliation: Prasad Thotton Veedu, Ashu Seith Bhalla, Arundeep Arora, Divya Singh, Arun Kumar Gupta, Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Arundeep
authors.initials: A
authors.lastname: Arora
authors.affiliation: Prasad Thotton Veedu, Ashu Seith Bhalla, Arundeep Arora, Divya Singh, Arun Kumar Gupta, Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Divya
authors.initials: D
authors.lastname: Singh
authors.affiliation: Prasad Thotton Veedu, Ashu Seith Bhalla, Arundeep Arora, Divya Singh, Arun Kumar Gupta, Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Arun Kumar
authors.initials: AK
authors.lastname: Gupta
keywords: Children; Computed tomography; Primary tuberculosis; Pulmonary; Tuberculosis