title: FeCl3-promoted carboxamidation and cyclization of aryl isonitriles with formamides toward phenanthridine-6-carboxamides.
abstract: An iron-promoted tandem carboxamidation and cyclization between aryl isonitriles and formamides has been developed. The one-pot strategy can be applied to a wide range of 2-isocyanobiphenyls and formamides with excellent functional group tolerance for the synthesis of phenanthridine-6-carboxamides in moderate to excellent yields.
authors.affiliation: College of Chemistry and Materials Engineering, Wenzhou University , Wenzhou 325035, China.
authors.forename: Hai-Yong
authors.initials: HY
authors.lastname: Tu
authors.forename: Yu-Rong
authors.initials: YR
authors.lastname: Liu
authors.forename: Jing-Jing
authors.initials: JJ
authors.lastname: Chu
authors.forename: Bo-Lun
authors.initials: BL
authors.lastname: Hu
authors.forename: Xing-Guo
authors.initials: XG
authors.lastname: Zhang
mesh_terms: D002384:Catalysis; D002712:Chlorides / Q000737:chemistry*; D003500:Cyclization; D005290:Ferric Compounds / Q000737:chemistry*; D005559:Formamides / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D010617:Phenanthridines / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D002712:Chlorides; D005290:Ferric Compounds; D005559:Formamides; D009570:Nitriles; D010617:Phenanthridines; C024555:ferric chloride