title: [Peculiarities of serum lipid profile in patients with thyroid pathology professionally exposed to low-dose radiation].
abstract: The study included 90 patients with coronary heart disease (CHD) with NYHA FC I-II cardiac insufficiency professionally exposed to ionizing radiation (IR). 30 patients had isolated CHD, 30 presented with CHD and concomitant euthyroid autoimmune thyroiditis (ALT) and 30 with hypothyroid AIT. The control group consisted of 30 patients with the same pathologies unexposed to IR. Peculiarities of serum lipid profile in the patients of all groups were investigated. It was shown that professional exposure to low-dose radiation had no appreciable effect on the lipid spectrum in professionals with CHD even if it combines with AIT without hormonal disorders (euthyroidism). The only clinically significant effect of IR was hypothyroidism in patients with CDH and AIT. Even then, marked atherogenic changes were diagnosed only in those cases where adequate replacement therapy failed to totally compensate for hormonal insufficiency.
authors.forename: M A
authors.initials: MA
authors.lastname: Vlasenko
authors.forename: V S
authors.initials: VS
authors.lastname: Kulinich
mesh_terms: D000368:Aged; D003327:Coronary Disease / Q000097:blood*; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000097:blood*; D050356:Lipid Metabolism / Q000528:radiation effects*; D008055:Lipids / Q000097:blood* / Q000528:radiation effects; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D011829:Radiation Dosage; D013967:Thyroiditis, Autoimmune / Q000097:blood*
chemical_list: D008055:Lipids