title: Single-family room care and neurobehavioral and medical outcomes in preterm infants.
abstract: OBJECTIVE
  To determine whether a single-family room (SFR) NICU, including factors associated with the change to a SFR NICU, is associated with improved medical and neurobehavioral outcomes.
  
  
  METHODS
  Longitudinal, prospective, quasi-experimental cohort study conducted between 2008 and 2012 comparing medical and neurobehavioral outcomes at discharge in infants born <1500 g. Participants included 151 infants in an open-bay NICU and 252 infants after transition to a SFR NICU. Structural equation modeling was used to determine the role of mediators of relations between type of NICU and medical and neurobehavioral outcomes.
  
  
  RESULTS
  Statistically significant results (all Ps ≤.05) showed that infants in the SFR NICU weighed more at discharge, had a greater rate of weight gain, required fewer medical procedures, had a lower gestational age at full enteral feed and less sepsis, showed better attention, less physiologic stress, less hypertonicity, less lethargy, and less pain. NICU differences in weight at discharge, and rate of weight gain were mediated by increased developmental support; differences in number of medical procedures were mediated by increased maternal involvement. NICU differences in attention were mediated by increased developmental support. Differences in stress and pain were mediated by maternal involvement. Nurses reported a more positive work environment and attitudes in the SFR NICU.
  
  
  CONCLUSIONS
  The SFR is associated with improved neurobehavioral and medical outcomes. These improvements are related to increased developmental support and maternal involvement.
authors.affiliation: Brown Center for the Study of Children at Risk, Departments of Pediatrics, and Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, Rhode Island; and Department of Pediatrics, Women & Infants Hospital of Rhode Island, Providence, Rhode Island barry_lester@brown.edu.
authors.forename: Barry M
authors.initials: BM
authors.lastname: Lester
authors.affiliation: Brown Center for the Study of Children at Risk, Departments of Pediatrics, and Department of Pediatrics, Women & Infants Hospital of Rhode Island, Providence, Rhode Island.
authors.forename: Katheleen
authors.initials: K
authors.lastname: Hawes
authors.affiliation: Brown Center for the Study of Children at Risk, Departments of Pediatrics, and Department of Pediatrics, Women & Infants Hospital of Rhode Island, Providence, Rhode Island.
authors.forename: Beau
authors.initials: B
authors.lastname: Abar
authors.affiliation: Brown Center for the Study of Children at Risk, Department of Pediatrics, Women & Infants Hospital of Rhode Island, Providence, Rhode Island.
authors.forename: Mary
authors.initials: M
authors.lastname: Sullivan
authors.affiliation: Brown Center for the Study of Children at Risk, Department of Pediatrics, Women & Infants Hospital of Rhode Island, Providence, Rhode Island.
authors.forename: Robin
authors.initials: R
authors.lastname: Miller
authors.affiliation: Brown Center for the Study of Children at Risk, Departments of Pediatrics, and Department of Pediatrics, Women & Infants Hospital of Rhode Island, Providence, Rhode Island.
authors.forename: Rosemarie
authors.initials: R
authors.lastname: Bigsby
authors.affiliation: Departments of Pediatrics, and Department of Pediatrics, Women & Infants Hospital of Rhode Island, Providence, Rhode Island.
authors.forename: Abbot
authors.initials: A
authors.lastname: Laptook
authors.affiliation: Brown Center for the Study of Children at Risk, Departments of Pediatrics, and Department of Pediatrics, Women & Infants Hospital of Rhode Island, Providence, Rhode Island.
authors.forename: Amy
authors.initials: A
authors.lastname: Salisbury
authors.affiliation: Department of Pediatrics, Women & Infants Hospital of Rhode Island, Providence, Rhode Island.
authors.forename: Marybeth
authors.initials: M
authors.lastname: Taub
authors.affiliation: Brown Center for the Study of Children at Risk, Departments of Pediatrics, and Department of Pediatrics, Women & Infants Hospital of Rhode Island, Providence, Rhode Island.
authors.forename: Linda L
authors.initials: LL
authors.lastname: Lagasse
authors.affiliation: Departments of Pediatrics, and Department of Pediatrics, Women & Infants Hospital of Rhode Island, Providence, Rhode Island.
authors.forename: James F
authors.initials: JF
authors.lastname: Padbury
mesh_terms: D015331:Cohort Studies; D005260:Female; D006801:Humans; D018730:Infant Behavior / Q000502:physiology / Q000523:psychology*; D007231:Infant, Newborn; D007234:Infant, Premature / Q000254:growth & development / Q000523:psychology*; D007363:Intensive Care Units, Neonatal / Q000592:standards* / Q000639:trends; D008137:Longitudinal Studies; D008297:Male; D010351:Patient Discharge / Q000639:trends; D010362:Patients' Rooms / Q000592:standards* / Q000639:trends; D011446:Prospective Studies; D016896:Treatment Outcome
keywords: developmental support; maternal involvement; medical outcome; neurobehavior; preterm infant; single-family room NICU