title: The effectiveness of oral essential aminoacids and aminoacids containing dialysate in peritoneal dialysis.
abstract: OBJECTIVE
  Oral essential amino acids (AAs) containing supplements (EAS) and AA containing dialysate (ACD) are frequently used in peritoneal dialysis (PD) patients with malnutrition. The present study was conducted to investigate two strategies and compare their effects on the malnutrition status of PD patients.
  
  
  METHODS
  A total of 31 EAS, 14 ACD patients were enrolled in this study. Serum albumin levels were lower than 3.5 g/dL in all subjects. EAS group patients took five pills containing AAs three times a day with meals. In the other, 2.000 cc of 1.1% ACD was given to patients daily during the study. Demographic and laboratory parameters were analyzed and compared at baseline and 6th month.
  
  
  RESULTS
  Significant increases in BMI, albumin, and protein in both groups. Mean albumin levels increased significantly by 0.54 g/dL in ACD group (p < 0.005) and 0.49 g/dL in EAS group (p < 0.001) following 6 months. Mean albumin and delta albumin levels did not differ between two groups.
  
  
  CONCLUSIONS
  These strategies may play an important role in increasing albumin levels and improving the nutritional status of PD patients.
authors.affiliation: Department of Nephrology, Ankara Educational and Training Hospital , Ankara , Turkey .
authors.forename: Selman
authors.initials: S
authors.lastname: Unverdi
authors.forename: Mevlut
authors.initials: M
authors.lastname: Ceri
authors.forename: Ebru
authors.initials: E
authors.lastname: Uz
authors.forename: Bulent
authors.initials: B
authors.lastname: Akgul
authors.forename: Mustafa
authors.initials: M
authors.lastname: Altay
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Kirac
authors.forename: Ali
authors.initials: A
authors.lastname: Akcay
authors.forename: Murat
authors.initials: M
authors.lastname: Duranay
mesh_terms: D000328:Adult; D000601:Amino Acids, Essential / Q000008:administration & dosage / Q000627:therapeutic use*; D015314:Dialysis Solutions / Q000737:chemistry*; D019587:Dietary Supplements; D005260:Female; D006801:Humans; D008297:Male; D044342:Malnutrition / Q000097:blood / Q000628:therapy*; D008875:Middle Aged; D009752:Nutritional Status; D010530:Peritoneal Dialysis / Q000379:methods*; D011506:Proteins; D012189:Retrospective Studies; D012709:Serum Albumin
chemical_list: D000601:Amino Acids, Essential; D015314:Dialysis Solutions; D011506:Proteins; D012709:Serum Albumin
keywords: Albumin; amino acid; dialysate; malnutrition; peritoneal dialysis