title: Effects of different biomaterials on augmented bone volume resorptions.
abstract: OBJECTIVE
  The aim of this study was to assess the effects of platelet-rich fibrin (PRF), deproteinized bovine bone graft (DBBG), and biphasic calcium phosphate (BCP) biomaterials on total volume resorption levels and bone augmentation.
  
  
  METHODS
  Nine New Zealand rabbits were divided into three groups (PRF, DBBG, and BCP). Two titanium barriers were fixed bilaterally to each rabbit's calvarium; a total of 18 titanium barriers were used. All barriers were removed on the 90th day. Computed tomography (CT) images of the animals were taken on the 90th, 120th, 150th, and 180th days.
  
  
  RESULTS
  When the resorption level of the total volume in all groups on the 120th, 150th, and 180th days was compared with that of the 90th day, no significant differences among all groups were found in all intervals. According to the total volume on the 90th and 180th days, statistically significant differences between groups DBBG and BCP were not found; however, statistically significant differences were found between group PRF and the others groups (P < 0.001). On the other hand, there were statistically significant differences in regenerated bone area between group PRF and BCP.
  
  
  CONCLUSIONS
  According to the results of this study, grafts such as DBBG or BCP must be used to augment bone volume sufficiently in guided bone regeneration.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Bezmialem Vakif University, İstanbul, Turkey.
authors.forename: Seref
authors.initials: S
authors.lastname: Ezirganli
authors.affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Bezmialem Vakif University, İstanbul, Turkey.
authors.forename: Hakki O
authors.initials: HO
authors.lastname: Kazancioglu
authors.affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Bezmialem Vakif University, İstanbul, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Mihmanli
authors.affiliation: Department of Radiology, Faculty of Medicine, Bezmialem Vakif University, İstanbul, Turkey.
authors.forename: Rasul
authors.initials: R
authors.lastname: Sharifov
authors.affiliation: Department of Histology and Embryology, Faculty of Medicine, Bezmialem Vakif University, İstanbul, Turkey.
authors.forename: Mehmet S
authors.initials: MS
authors.lastname: Aydin
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000494:pharmacology*; D001862:Bone Resorption / Q000188:drug therapy*; D018786:Bone Substitutes / Q000494:pharmacology*; D004659:Enbucrilate / Q000494:pharmacology; D005337:Fibrin / Q000494:pharmacology*; D006882:Hydroxyapatites / Q000494:pharmacology*; D008297:Male; D008903:Minerals / Q000494:pharmacology*; D011817:Rabbits; D012886:Skull / Q000000981:diagnostic imaging / Q000601:surgery*; D014057:Tomography, X-Ray Computed
chemical_list: C077540:Bio-Oss; D001672:Biocompatible Materials; D018786:Bone Substitutes; D006882:Hydroxyapatites; D008903:Minerals; C074950:hydroxyapatite-beta tricalcium phosphate; D005337:Fibrin; D004659:Enbucrilate
keywords: bone grafts; guided bone regeneration; histomorphometry; platelet-rich fibrin; volumetrıc tomography