title: [Study on transient absorption spectrum of tungsten nanoparticle with HepG2 tumor cell].
abstract: Significance of this study lies in tungsten nano materials can be used as a preliminary innovative medicines applied basic research. This paper investigated the inhibition of tungsten nanoparticles which effected on human hepatoma HepG2 cells by MTT. The authors use transient absorption spectroscopy (TAS) technology absorption and emission spectra characterization of charge transfer between nanoparticles and tumor cell. The authors discussed the role of the tungsten nanoparticles in the tumor early detection of the disease and its anti-tumor properties. In the HepG2 experiments system, 100-150 microg x mL(-1) is the best drug concentration of anti-tumor activity which recact violently within 6 hours and basically completed in 24 hours. The results showed that transient absorption spectroscopy can be used as tumor detection methods and characterization of charge transfer between nano-biosensors and tumor cells. Tungsten nanoparticles have potential applications as anticancer drugs.
authors.forename: Lin
authors.initials: L
authors.lastname: Cao
authors.forename: Xiao-Ning
authors.initials: XN
authors.lastname: Shu
authors.forename: Dong
authors.initials: D
authors.lastname: Liang
authors.forename: Cong
authors.initials: C
authors.lastname: Wang
mesh_terms: D000970:Antineoplastic Agents; D056945:Hep G2 Cells; D006801:Humans; D008113:Liver Neoplasms / Q000378:metabolism*; D053758:Nanoparticles; D014414:Tungsten
chemical_list: D000970:Antineoplastic Agents; D014414:Tungsten