title: Chiral palladacycle catalysts generated on a single-handed helical polymer skeleton for asymmetric arylative ring opening of 1,4-epoxy-1,4-dihydronaphthalene.
abstract: Post-polymerization CH activation of poly(quinoxaline-2,3-diyl)-based helically chiral phosphine ligands (PQXphos) with palladium(II) acetate afforded chiral phosphapalladacycles quantitatively. In situ generated palladacycles exhibited enantioselectivities up to 94 % ee in the palladium-catalyzed asymmetric ring-opening arylation of 1,4-epoxy-1,4-dihydronaphthalenes with arylboronic acids.
authors.affiliation: Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510 (Japan).
authors.forename: Takeshi
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Yuto
authors.initials: Y
authors.lastname: Akai
authors.forename: Michinori
authors.initials: M
authors.lastname: Suginome
keywords: asymmetric synthesis; helical structures; ligand design; palladacycles; polymer catalyst