title: Corticosterone and propranolol's role on taste recognition memory.
abstract: Taste recognition is a robust procedure to study learning and memory processes, as well as the different stages involved in them, i.e. encoding, storage and recall. Considerable evidence indicates that adrenal hormones and the noradrenergic system play an important role in aversive and appetitive memory formation in rats and humans. The present experiments were designed to characterize the effects of immediate post training corticosterone (Experiment 1) and propranolol administration (Experiment 2 and 3) on taste recognition memory. Administration of a high dose of corticosterone (5mg/kg, sc) impairs consolidation of taste memory, but the low and moderate doses (1 and 3mg/kg, sc) didn't affect it. On the other hand, immediate post-training administration of propranolol (1 and 2mg/kg, ip) impaired taste recognition memory. These effects were time-dependent since no effects were seen when drug administration was delayed 3h after training. These findings support the importance of stress hormones and noradrenergic system on the modulation of taste memory consolidation.
authors.affiliation: Lab. de Psicología Experimental y Aplicada (PSEA), Instituto de Investigaciones Médicas A Lanari, (IDIM), CONICET-UBA, Argentina; Lab. de los Procesos de Memoria, Fac. de Farmacia y Bioquímica, UBA, Argentina. Electronic address: elianaruetti@gmail.com.
authors.forename: E
authors.initials: E
authors.lastname: Ruetti
authors.affiliation: Lab. de Psicología Experimental y Aplicada (PSEA), Instituto de Investigaciones Médicas A Lanari, (IDIM), CONICET-UBA, Argentina; Lab. de los Procesos de Memoria, Fac. de Farmacia y Bioquímica, UBA, Argentina.
authors.forename: N
authors.initials: N
authors.lastname: Justel
authors.affiliation: Lab. de Psicología Experimental y Aplicada (PSEA), Instituto de Investigaciones Médicas A Lanari, (IDIM), CONICET-UBA, Argentina; Lab. de los Procesos de Memoria, Fac. de Farmacia y Bioquímica, UBA, Argentina.
authors.forename: A
authors.initials: A
authors.lastname: Mustaca
authors.affiliation: Lab. de Psicología Experimental y Aplicada (PSEA), Instituto de Investigaciones Médicas A Lanari, (IDIM), CONICET-UBA, Argentina; Lab. de los Procesos de Memoria, Fac. de Farmacia y Bioquímica, UBA, Argentina.
authors.forename: M
authors.initials: M
authors.lastname: Boccia
mesh_terms: D000818:Animals; D003345:Corticosterone / Q000494:pharmacology*; D008297:Male; D008568:Memory / Q000187:drug effects / Q000502:physiology; D011433:Propranolol / Q000494:pharmacology*; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D021641:Recognition, Psychology / Q000187:drug effects* / Q000502:physiology; D013649:Taste / Q000187:drug effects* / Q000502:physiology
chemical_list: D011433:Propranolol; D003345:Corticosterone
keywords: Corticosterone; Flavor; Memory; Propranolol; Rats; Taste recognition test