title: Strategy for prevention of cancers of the esophagus.
abstract: The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on the animal reflux-inflammation models for Barrett's esophagus and esophageal adenocarcinoma; genomic/epigenomic analyses; eflornithine-based combinations; the molecular derangements that promote neoplastic transformation; the role of COX-2 inhibitors, proton pump inhibitors, and phase II trials in Barrett's adenocarcinoma; statins in chemoprevention and treatment of esophageal cancer; and biomarkers as potential targets in Barrett's adenocarcinoma.
authors.affiliation: National Center for Global Health and Medicine, Tokyo, Japan.
authors.forename: Junichi
authors.initials: J
authors.lastname: Akiyama
authors.forename: Leo
authors.initials: L
authors.lastname: Alexandre
authors.forename: Anushka
authors.initials: A
authors.lastname: Baruah
authors.forename: Navtej
authors.initials: N
authors.lastname: Buttar
authors.forename: Raghav
authors.initials: R
authors.lastname: Chandra
authors.forename: Allan B
authors.initials: AB
authors.lastname: Clark
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Hart
authors.forename: Ernest
authors.initials: E
authors.lastname: Hawk
authors.forename: Daniela
authors.initials: D
authors.lastname: Kandioler
authors.forename: Sonja
authors.initials: S
authors.lastname: Kappel
authors.forename: Sheila K
authors.initials: SK
authors.lastname: Krishnadath
authors.forename: Anamay
authors.initials: A
authors.lastname: Sharma
authors.forename: Ishtpreet
authors.initials: I
authors.lastname: Singh
authors.forename: Danielle
authors.initials: D
authors.lastname: Straub
authors.forename: George
authors.initials: G
authors.lastname: Triadafilopoulos
authors.forename: Asad
authors.initials: A
authors.lastname: Umar
authors.forename: Brigitte
authors.initials: B
authors.lastname: Wolf
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001471:Barrett Esophagus / Q000175:diagnosis / Q000378:metabolism / Q000517:prevention & control; D014408:Biomarkers, Tumor / Q000378:metabolism; D002471:Cell Transformation, Neoplastic / Q000378:metabolism; D052246:Cyclooxygenase 2 Inhibitors / Q000627:therapeutic use; D000518:Eflornithine / Q000627:therapeutic use; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000517:prevention & control*; D005764:Gastroesophageal Reflux / Q000175:diagnosis / Q000378:metabolism / Q000517:prevention & control; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D010297:Paris; D054328:Proton Pump Inhibitors / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor; D052246:Cyclooxygenase 2 Inhibitors; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D054328:Proton Pump Inhibitors; D000518:Eflornithine
keywords: Barrett's adenocarcinoma; COXIBs, PPIs; OESO; animal reflux-inflammation models; biomarkers; elofrnithine; statins