title: Primary intermediate-grade cardiac myxofibrosarcoma with osseous metaplasia: an extremely rare occurrence with a previously unreported feature.
abstract: Primary cardiac myxofibrosarcoma (MFS) is a very rare cardiac tumor with no more than 22 cases reported in the literature, including our case. We report an MFS arising in the left atrium in a 65-year-old woman who presented with pneumonia and cardiac failure. The 9.5-cm mass was diagnosed by echocardiogram. Histopathology examination showed an intermediate-grade MFS with osseous metaplasia, a feature that has not been reported before.
authors.affiliation: Department of Pathology, Hospital de Especialidades, CMN La Raza, Calle Seris s/n, Col. La Raza, C.P. 02990, Delegación Azcapotzalco, México D.F., Mexico. Electronic address: magdasaur@hotmail.com.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Sanchez-Uribe
authors.affiliation: Department of Pathology, San Cecilio University Hospital. Avenida Madrid 11, Granada, Spain. Electronic address: jaretamero@mac.com.
authors.forename: Juan Antonio
authors.initials: JA
authors.lastname: Retamero
authors.affiliation: Department of Cardiology and Echocardiogram, Hospital de Especialidades, CMN La Raza, Calle Seris s/n, Col. La Raza, C.P. 02990, Delegación Azcapotzalco, México D.F., Mexico. Electronic address: joaqmd.gl@gmail.com.
authors.forename: J
authors.initials: J
authors.lastname: Gomez Leon
authors.affiliation: Department of Cardiology and Echocardiogram, Hospital de Especialidades, CMN La Raza, Calle Seris s/n, Col. La Raza, C.P. 02990, Delegación Azcapotzalco, México D.F., Mexico. Electronic address: hexenar@gmail.com.
authors.forename: Jorge
authors.initials: J
authors.lastname: Montoya Perez
authors.affiliation: Department of Pathology, Hospital de Especialidades, CMN La Raza, Calle Seris s/n, Col. La Raza, C.P. 02990, Delegación Azcapotzalco, México D.F., Mexico. Electronic address: enoequ@hotmail.com.
authors.forename: Enoe
authors.initials: E
authors.lastname: Quiñonez
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D004452:Echocardiography; D005260:Female; D005354:Fibrosarcoma / Q000000981:diagnostic imaging / Q000473:pathology*; D006325:Heart Atria / Q000473:pathology; D006338:Heart Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008679:Metaplasia; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging; D010010:Osteoclasts / Q000473:pathology
keywords: Atrium; Intermediate-grade; Myxofibrosarcoma; Osseous metaplasia