title: Detection of vaccine-derived rotavirus strains in nonimmunocompromised children up to 3-6 months after RotaTeq® vaccination.
abstract: We conducted a survey on the presence of RotaTeq vaccine viruses in infants hospitalized with respiratory infection, and detected shedding in 17% of children (<2 years of age) who had ever received the vaccine. The latest detection was at the age of 8 months. We conclude that asymptomatic long-time shedding of RotaTeq viruses is not uncommon, and is particularly associated with genotype G1.
authors.affiliation: From the Vaccine Research Center, University of Tampere School of Medicine, Tampere, Finland.
authors.forename: Jukka
authors.initials: J
authors.lastname: Markkula
authors.forename: Maria
authors.initials: M
authors.lastname: Hemming
authors.forename: Timo
authors.initials: T
authors.lastname: Vesikari
mesh_terms: D000956:Antigens, Viral / Q000235:genetics / Q000276:immunology; D036022:Capsid Proteins / Q000235:genetics / Q000276:immunology; D005260:Female; D005838:Genotype; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D012401:Rotavirus / Q000235:genetics* / Q000276:immunology*; D012400:Rotavirus Infections / Q000517:prevention & control*; D022243:Rotavirus Vaccines / Q000008:administration & dosage / Q000276:immunology*; D014611:Vaccination
chemical_list: D000956:Antigens, Viral; D036022:Capsid Proteins; D022243:Rotavirus Vaccines; C061332:VP6 protein, Rotavirus