title: Planar cell polarity: the importance of getting it backwards.
abstract: The core and Fat-Dachsous signaling systems locally align planar cell polarities in Drosophila epithelia. Three recent papers address how coupling between these systems can be altered and reversed by the products of the gene prickle.
authors.affiliation: Department of Zoology, University of Wisconsin, Madison, WI 53706 USA. Electronic address: ssblair@wisc.edu.
authors.forename: Seth S
authors.initials: SS
authors.lastname: Blair
mesh_terms: D000818:Animals; D004268:DNA-Binding Proteins / Q000235:genetics*; D029721:Drosophila Proteins / Q000235:genetics*; D004331:Drosophila melanogaster / Q000502:physiology*; D018507:Gene Expression Regulation, Developmental; D060588:LIM Domain Proteins / Q000235:genetics*; D015398:Signal Transduction; D014921:Wings, Animal / Q000502:physiology*
chemical_list: D004268:DNA-Binding Proteins; D029721:Drosophila Proteins; D060588:LIM Domain Proteins; C121600:pk protein, Drosophila