title: The Oxeatamides: nitrogenous spongian diterpenes from the New Zealand marine sponge Darwinella oxeata.
abstract: As part of our ongoing search for novel and bioactive compounds from New Zealand marine organisms, we investigated the extracts of the sponge Darwinella oxeata. NMR-guided fractionation led to the isolation of nine new nitrogenous spongian diterpenes, oxeatamide A (1), iso-oxeatamide A (2), oxeatamides B-G (3-8), and oxeatamide A 23-methyl ester (9), as well as two known compounds, membranolides C and D (10, 11).
authors.affiliation: School of Chemical and Physical Sciences, Victoria University of Wellington , P.O. Box 600, Wellington, New Zealand.
authors.forename: Joanna M
authors.initials: JM
authors.lastname: Wojnar
authors.forename: Katie O
authors.initials: KO
authors.lastname: Dowle
authors.forename: Peter T
authors.initials: PT
authors.lastname: Northcote
mesh_terms: D000818:Animals; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D008386:Marine Biology; D015394:Molecular Structure; D009520:New Zealand; D019906:Nuclear Magnetic Resonance, Biomolecular; D011161:Porifera / Q000737:chemistry*
chemical_list: D004224:Diterpenes; C489101:membranolide C; C000593740:oxeatamide A