title: Bone mineral density is not associated with musculoskeletal pain in postmenopausal Korean women aged ≥50 years.
abstract: Although many studies reported improvement of back pain after osteoporosis treatment, there is insufficient evidence to determine whether osteoporosis is painful. We investigated whether bone mineral density correlated with musculoskeletal pain in postmenopausal Korean women aged ≥50 years. Data for postmenopausal women aged ≥50 years were obtained from the fifth Korea National Health and Nutrition Examination Survey database. Demographics, Kellgren-Lawrence grade, and numeric rating scale for pain in the hip and knee joints, presence of back pain, and activity level were analyzed. Only subjects with dual-energy X-ray absorptiometry scans and hip and knee radiographs were included. Those with malignancy, pain medication use, or a history of fragility fractures were excluded. After univariate analysis, multiple linear regression analysis was performed to examine the significant factors correlated with the degree of hip and knee pain. Binary logistic regression analysis was performed to identify factors significantly associated with the presence of back pain. In total, 387 women were included in the data analysis. Age (p = 0.005) was the only significant factor correlated with the intensity of hip pain, while Kellgren-Lawrence grade (p < 0.001) was the only significant factor correlated with knee pain intensity in multiple regression analysis. Binary logistic regression analysis showed that age (p = 0.002) was the only significant factor associated with the presence of back pain. Musculoskeletal pain was not affected by or associated with the bone mineral density (BMD) of the affected body part in postmenopausal Korean women aged ≥50 years after adjusting for the degree of osteoarthritis.
authors.affiliation: Department of Orthopedic Surgery, Seoul National University Bundang Hospital, 300 Gumi-Dong, Bundang-Gu, Sungnam, Kyungki, 463-707, South Korea.
authors.forename: Kyoung Min
authors.initials: KM
authors.lastname: Lee
authors.forename: Chin Youb
authors.initials: CY
authors.lastname: Chung
authors.forename: Soon-Sun
authors.initials: SS
authors.lastname: Kwon
authors.forename: Tae Gyun
authors.initials: TG
authors.lastname: Kim
authors.forename: In Hyeok
authors.initials: IH
authors.lastname: Lee
authors.forename: Ki Jin
authors.initials: KJ
authors.lastname: Jung
authors.forename: Jin Woo
authors.initials: JW
authors.lastname: Park
authors.forename: Sang Young
authors.initials: SY
authors.lastname: Moon
authors.forename: Moon Seok
authors.initials: MS
authors.lastname: Park
mesh_terms: D000368:Aged; D015519:Bone Density / Q000502:physiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D059352:Musculoskeletal Pain / Q000150:complications / Q000503:physiopathology*; D015663:Osteoporosis, Postmenopausal / Q000150:complications / Q000503:physiopathology*; D017698:Postmenopause / Q000502:physiology*; D056910:Republic of Korea