title: Characterization of Staphylococcus epidermidis phage vB_SepS_SEP9 - a unique member of the Siphoviridae family.
abstract: Relatively few phages (<10) of coagulase negative staphylococci (CoNS) have been described. Staphylococcus epidermidis phage vB_SepS_SEP9 is a siphovirus with a unique morphology as a staphylococcal phage, possessing a very long tail. Its genome is unique and unrelated to any phage genomes deposited in public databases. It appears to encode a nonfunctional integrase. Due to the not having a recognizable lysogeny module, the phage is unable lysogenize. The genome comprises 129 coding sequences (CDS), 46 of which have an assigned function and 59 are unique. Its unique morphology and genome led to the proposal of the establishment of a new Siphoviridae genus named "Sep9likevirus".
authors.affiliation: CEB - Centre of Biological Engineering, LIBRO - Laboratory of Research in Biofilms Rosário Oliveira, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
authors.forename: Luís D R
authors.initials: LD
authors.lastname: Melo
authors.affiliation: CEB - Centre of Biological Engineering, LIBRO - Laboratory of Research in Biofilms Rosário Oliveira, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
authors.forename: Sanna
authors.initials: S
authors.lastname: Sillankorva
authors.affiliation: Department of Microbiology, Immunology and Infectiology, Faculty of Medicine, Laval University, Québec, QC G1X 4C6, Canada.
authors.forename: Hans-Wolfgang
authors.initials: HW
authors.lastname: Ackermann
authors.affiliation: Public Health Agency of Canada, Laboratory for Foodborne Zoonoses, Guelph, ON N1G 3W4, Canada; Department of Molecular and Cellular Biology, University of Guelph, ON N1G 2W1, Canada.
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Kropinski
authors.affiliation: CEB - Centre of Biological Engineering, LIBRO - Laboratory of Research in Biofilms Rosário Oliveira, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
authors.forename: Joana
authors.initials: J
authors.lastname: Azeredo
authors.affiliation: CEB - Centre of Biological Engineering, LIBRO - Laboratory of Research in Biofilms Rosário Oliveira, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal. Electronic address: nunocerca@ceb.uminho.pt.
authors.forename: Nuno
authors.initials: N
authors.lastname: Cerca
mesh_terms: D004279:DNA, Viral / Q000737:chemistry / Q000235:genetics; D005814:Genes, Viral; D016679:Genome, Viral; D058977:Molecular Sequence Annotation; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA; D017906:Siphoviridae / Q000235:genetics* / Q000302:isolation & purification* / Q000648:ultrastructure; D013204:Staphylococcus Phages / Q000235:genetics* / Q000302:isolation & purification* / Q000648:ultrastructure; D013212:Staphylococcus epidermidis / Q000821:virology*
chemical_list: D004279:DNA, Viral
keywords: Bacteriophages; Genomics; Siphoviridae; Staphylococcus epidermidis