title: Laboratory evaluation of three rapid diagnostic tests for dual detection of HIV and Treponema pallidum antibodies.
abstract: The performance of three research-use-only, dual HIV and syphilis rapid diagnostic tests (RDTs) was evaluated for 150 patient serum samples and compared to reference HIV and Treponema pallidum antibody detection methods. The RDTs performed comparably, with sensitivities of 93 to 99% and specificities of 97 to 100%. The kappa statistic between the RDTs was 0.95.
authors.affiliation: Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA rhumphries@mednet.ucla.edu.
authors.forename: Romney M
authors.initials: RM
authors.lastname: Humphries
authors.affiliation: Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
authors.forename: Jennifer S
authors.initials: JS
authors.lastname: Woo
authors.affiliation: Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
authors.forename: Jun Ho
authors.initials: JH
authors.lastname: Chung
authors.affiliation: Department of Infectious Diseases, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
authors.forename: Anita
authors.initials: A
authors.lastname: Sokovic
authors.affiliation: Department of Infectious Diseases, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
authors.forename: Claire C
authors.initials: CC
authors.lastname: Bristow
authors.affiliation: Department of Infectious Diseases, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
authors.forename: Jeffrey D
authors.initials: JD
authors.lastname: Klausner
mesh_terms: D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood*; D003955:Diagnostic Tests, Routine / Q000379:methods*; D005260:Female; D006678:HIV / Q000276:immunology; D015483:HIV Antibodies / Q000097:blood*; D015658:HIV Infections / Q000175:diagnosis* / Q000821:virology; D006801:Humans; D007118:Immunoassay / Q000379:methods; D008297:Male; D012680:Sensitivity and Specificity; D013587:Syphilis / Q000175:diagnosis* / Q000382:microbiology; D014210:Treponema pallidum / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial; D015483:HIV Antibodies