title: A general approach to spirolactonized Si-rhodamines.
abstract: A general approach has been developed for the synthesis of spirolactonized Si-rhodamines (SiRBs). The alternative synthetic route provides a facile opportunity to access various s bearing ring-expanded scaffolds and substituents for conjugation. By click reaction, a near-infrared (NIR) mitochondrial tracker was prepared, displaying specific mitochondrial staining in cells.
authors.affiliation: Department of Organic Chemistry, College of Pharmacy, Second Military Medical University, Guohe Road 325, Shanghai 200433, P.R. China. wangting1983927@gmail.com wuqy6439@sohu.com.
authors.forename: Baogang
authors.initials: B
authors.lastname: Wang
authors.forename: Xiaoyun
authors.initials: X
authors.lastname: Chai
authors.forename: Weiwei
authors.initials: W
authors.lastname: Zhu
authors.forename: Ting
authors.initials: T
authors.lastname: Wang
authors.forename: Qiuye
authors.initials: Q
authors.lastname: Wu
mesh_terms: D000818:Animals; D045744:Cell Line, Tumor; D057930:Click Chemistry; D005456:Fluorescent Dyes / Q000737:chemistry* / Q000494:pharmacology; D056945:Hep G2 Cells; D006801:Humans; D051379:Mice; D008928:Mitochondria / Q000378:metabolism; D012235:Rhodamines / Q000737:chemistry* / Q000494:pharmacology; D012825:Silicon / Q000737:chemistry* / Q000494:pharmacology; D013050:Spectrometry, Fluorescence
chemical_list: D005456:Fluorescent Dyes; D012235:Rhodamines; D012825:Silicon