title: Serum bone markers levels and bone mineral density in familial mediterranean Fever.
abstract: [Purpose] The aim of this study was to measure bone mineral density, serum and urinary bone turnover parameters, and to evaluate the influence of demographic and genetic factors on these parameters in FMF patients. [Subjects and Methods] Twenty-seven attack-free patients who were diagnosed with FMF (in accordance with Tel Hashomer criteria) were recruited at outpatient rheumatology clinics. We investigated whether there were any differences between the FMF patients and a control group in terms of lumbar and femur bone mineral density (BMD), standard deviation scores (Z scores and T scores) and bone markers. [Results] In terms of the median values of lumbar BMD (p = 0.21), lumbar T (p = 0.098) and Z (p = 0.109) scores, femoral neck BMD, femoral T and Z scores and total femur BMD, T (p = 0.788) and Z scores, there were no significant differences. [Conclusion] In our study, no statistically significant differences were found between FMF patients and a control group in terms of osteoporosis. The 25-OH vitamin D was found to be significantly lower in FMF patients than in the control group.
authors.affiliation: Department of Physıcal Therapy and Rehabılıtatıon, Bezm-i Alem Vakıf Foundatıon Unıversıty School of Medıcıne, Türkiye.
authors.forename: Teoman
authors.initials: T
authors.lastname: Aydın
authors.affiliation: Department of Physıcal Therapy and Rehabılıtatıon, Bezm-i Alem Vakıf Foundatıon Unıversıty School of Medıcıne, Türkiye.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Taspınar
authors.affiliation: Department of Physıcal Therapy and Rehabılıtatıon, Bezm-i Alem Vakıf Foundatıon Unıversıty School of Medıcıne, Türkiye.
authors.forename: Yildiz
authors.initials: Y
authors.lastname: Akbal
authors.affiliation: Department of Internal Medıcıne, Bezm-i Alem Vakıf Foundatıon Unıversıty School of Medıcıne, Türkiye.
authors.forename: Celaleddin
authors.initials: C
authors.lastname: Peru
authors.affiliation: Department of Physıcal Therapy and Rehabılıtatıon, Bezm-i Alem Vakıf Foundatıon Unıversıty School of Medıcıne, Türkiye.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Guler
authors.affiliation: Department of Bıoıstatistıcs, Bezm-i Alem Vakıf Foundatıon Unıversıty School of Medıcıne, Türkiye.
authors.forename: Omer
authors.initials: O
authors.lastname: Uysal
authors.affiliation: Acıbadem Universıty School of Medıcıne, Department of Molecular Bıology and Genetıcs, Türkiye.
authors.forename: M Cengiz
authors.initials: MC
authors.lastname: Yakıcıer
keywords: Bone mineral density; Familial mediterranean fever; Serum bone markers levels