title: (CF3CO)2O/CF3SO3H-mediated synthesis of 1,3-diketones from carboxylic acids and aromatic ketones.
abstract: A very simple and convenient reaction for 1,3-diketone preparation from carboxylic acids and aromatic ketones in TFAA/TfOH system is described. When the β-phenylpropionic acids were used as starting materials, they initially gave 1-indanones and then underwent further acylation with the formation of 2-(β-phenylpropionyl)-1-indanones as the main reaction products. In addition, the application of the proposed protocol allowed for the synthesis of selected polysubstituted pyrazoles in a one-pot procedure directly from acids and ketones.
authors.affiliation: Laboratory of Macrocyclic Receptors, Department of Chemistry, Moscow State University, Lenin's Hills, Moscow 119991, Russia.
authors.forename: JungKeun
authors.initials: J
authors.lastname: Kim
authors.affiliation: Laboratory of Macrocyclic Receptors, Department of Chemistry, Moscow State University, Lenin's Hills, Moscow 119991, Russia.
authors.forename: Elvira
authors.initials: E
authors.lastname: Shokova
authors.affiliation: Laboratory of Macrocyclic Receptors, Department of Chemistry, Moscow State University, Lenin's Hills, Moscow 119991, Russia.
authors.forename: Victor
authors.initials: V
authors.lastname: Tafeenko
authors.affiliation: Laboratory of Macrocyclic Receptors, Department of Chemistry, Moscow State University, Lenin's Hills, Moscow 119991, Russia.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Kovalev
keywords: 1,3-diketones; Claisen condensation; heterocycles; triflic acid; trifluoroacetic acid anhydride