title: Hypercalcaemia secondary to hypervitaminosis a in a patient with chronic renal failure.
abstract: Vitamin A toxicity is a well-described medical condition with a multitude of potential presenting signs and symptoms. It can be divided into acute and chronic toxicity. Serum vitamin A concentrations are raised in chronic renal failure even with ingestion of less than the usual toxic doses. Hypercalcaemia can occasionally be associated with high levels of vitamin A but it is rare. In this report, we describe a 67- year old female patient with chronic kidney disease who was taking vitamin A supplements for approximately 10 years. The patient had worsening of her chronic kidney disease over the last years and developed chronic hypercalcaemia. Her vitamin A level was elevated with a daily intake of 7000 IU. The vitamin A supplement was stopped. A few months later, vitamin A level diminished substantially and serum calcium levels returned to normal.
authors.affiliation: Oklahoma University Health Sciences Centre, 1100 N Lindsay, Oklahoma City, Oklahoma 73104, USA. dalia_hammoud@ouhsc.edu.
authors.forename: D
authors.initials: D
authors.lastname: Hammoud
authors.affiliation: Kansas University School of Medicine, Wichita, Kansas, USA.
authors.forename: B
authors.initials: B
authors.lastname: El Haddad
authors.affiliation: Kansas University School of Medicine, Wichita, Kansas, USA.
authors.forename: J
authors.initials: J
authors.lastname: Abdallah