title: Catalyst-free reductive amination of aromatic aldehydes with ammonium formate and Hantzsch ester.
abstract: The protocol of the reductive amination of aromatic aldehydes using ammonium formate and Hantzsch ester is described. It is a mild, convenient, acid- and catalyst-free system applied for the synthesis of both symmetric and asymmetric aromatic secondary amines.
authors.affiliation: School of Medical Engineering, School of Chemistry and Chemical Engineering, Hefei University of Technology, Hefei 230009, China. hjxu@hfut.edu.cn.
authors.forename: Pan-Pan
authors.initials: PP
authors.lastname: Zhao
authors.forename: Xin-Feng
authors.initials: XF
authors.lastname: Zhou
authors.forename: Jian-Jun
authors.initials: JJ
authors.lastname: Dai
authors.forename: Hua-Jian
authors.initials: HJ
authors.lastname: Xu
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000586:Amination; D002384:Catalysis; D004952:Esters / Q000737:chemistry; D005561:Formates / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction
chemical_list: D000447:Aldehydes; D004952:Esters; D005561:Formates; C030544:formic acid