title: Regioselectivity of Diels-Alder Reactions Between 6,7-Dehydrobenzofuran and 2-Substituted Furans.
abstract: We describe the first report of the generation of 6,7-dehydrobenzofuran (6,7-benzofuranyne) from 6,7-dihalobenzofurans via metal-halogen exchange and elimination, in a manner similar to our previous work with 6,7-indole arynes. This benzofuranyne undergoes highly regioselective Diels-Alder cycloadditions with 2-substituted furans.
authors.affiliation: Department of Chemistry, University of Missouri-Kansas City, 205 Spencer Chemical Laboratories, 5100 Rockhill Road, Kansas City, MO, 64110, USA ; The University of Kansas Center of Excellence in Chemical Methodologies and Library Development, Structural Biology Center, 2121 Simons Drive, Lawrence, Kansas 66047, USA.
authors.forename: Neil
authors.initials: N
authors.lastname: Brown
authors.affiliation: Department of Chemistry, University of Missouri-Kansas City, 205 Spencer Chemical Laboratories, 5100 Rockhill Road, Kansas City, MO, 64110, USA ; The University of Kansas Center of Excellence in Chemical Methodologies and Library Development, Structural Biology Center, 2121 Simons Drive, Lawrence, Kansas 66047, USA.
authors.forename: Keith R
authors.initials: KR
authors.lastname: Buszek