title: Effect of excess body weight on the genetic susceptibility to cancer.
abstract: Excess body weight and genetics play important roles in cancer susceptibility. Although several studies have reported on obesity and genetic variants as separate risk factors for cancer, very few studies have investigated the interaction between excess body weight and genetic variants in cancer susceptibility. In this review, we focus on the interplay between these 2 risk factors, which are a major determinant of the individual risk of cancer onset.
authors.affiliation: *Department of Molecular and Clinical Medicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden †Department of Experimental and Clinical Medicine ‡Clinical Nutrition Unit, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
authors.forename: Maria A
authors.initials: MA
authors.lastname: Burza
authors.forename: Rocco
authors.initials: R
authors.lastname: Spagnuolo
authors.forename: Tiziana
authors.initials: T
authors.lastname: Montalcini
authors.forename: Patrizia
authors.initials: P
authors.lastname: Doldo
authors.forename: Arturo
authors.initials: A
authors.lastname: Pujia
authors.forename: Stefano
authors.initials: S
authors.lastname: Romeo
mesh_terms: D001835:Body Weight; D059647:Gene-Environment Interaction; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000503:physiopathology; D009765:Obesity / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D012307:Risk Factors