title: Viral hepatitis among drug users in methadone maintenance: associated factors, vaccination outcomes, and interventions.
abstract: Drug users are at high risk of viral Hepatitis A, B, and C. The prevalence of Hepatitis A, Hepatitis B, and Hepatitis C, associated factors, and vaccine seroconversion among drug treatment program participants in a randomized controlled trial of hepatitis care coordination were examined. Of 489 participants, 44 and 47% required Hepatitis A/Hepatitis B vaccinations, respectively; 59% were Hepatitis C positive requiring linkage to care. Factors associated with serologic statuses, and vaccine seroconversion are reported; implications for strategies in drug treatment settings are discussed. Results suggest generalizable strategies for drug treatment programs to expand viral hepatitis screening, prevention, vaccination, and linkage to care.
authors.affiliation: a Chemical Dependency Institute, Mount Sinai Beth Israel , New York , New York , USA.
authors.forename: David C
authors.initials: DC
authors.lastname: Perlman
authors.forename: Ashly E
authors.initials: AE
authors.lastname: Jordan
authors.forename: Courtney
authors.initials: C
authors.lastname: McKnight
authors.forename: Christopher
authors.initials: C
authors.lastname: Young
authors.forename: Kevin L
authors.initials: KL
authors.lastname: Delucchi
authors.forename: James L
authors.initials: JL
authors.lastname: Sorensen
authors.forename: Don C
authors.initials: DC
authors.lastname: Des Jarlais
authors.forename: Carmen L
authors.initials: CL
authors.lastname: Masson
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006506:Hepatitis A / Q000276:immunology / Q000517:prevention & control*; D006509:Hepatitis B / Q000276:immunology / Q000517:prevention & control*; D006526:Hepatitis C / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008691:Methadone / Q000627:therapeutic use*; D008875:Middle Aged; D009518:New York / Q000453:epidemiology; D058850:Opiate Substitution Treatment; D015995:Prevalence; D012307:Risk Factors; D012495:San Francisco / Q000453:epidemiology; D019966:Substance-Related Disorders / Q000188:drug therapy*; D014761:Viral Hepatitis Vaccines
chemical_list: D014761:Viral Hepatitis Vaccines; D008691:Methadone
keywords: Hepatitis C; Viral hepatitis; methadone maintenance treatment program; vaccination