title: Laparoscopic versus open resection for transverse colon cancer.
abstract: BACKGROUND
  Previous large randomized controlled trials comparing laparoscopic (LR) and open resection (OR) for colon cancer have not specifically analyzed the outcomes in patients with transverse colon cancer. The aims of this study were to evaluate the feasibility and safety of LR transverse colon cancer resection and to compare our findings with the results available in the literature.
  
  
  METHODS
  We performed a retrospective analysis of consecutive patients undergoing LR or OR for histologically proven adenocarcinoma of the transverse colon.
  
  
  RESULTS
  A total of 123 patients were included in this study: 66 LR and 57 OR. Median operating time was similar in the two groups. Median blood loss was higher in the OR group, even though the difference was not statistically significant. The rate of conversion from LR to OR was 16.7 %. Return of bowel function occurred significantly earlier in the LR group. The incidence and severity of 30-day postoperative complications and mortality rates were similar in the two groups. The median hospital stay was significantly shorter in the LR group. There was a trend toward a greater number of lymph nodes harvested in the OR group than in the LR group, although the difference was not statistically significant. The time to first flatus and bowel movement was significantly earlier in the LR group. Five-year overall survival and disease-free survival rates were similar in the LR and OR groups (86.4 vs. 88.6 %, p = 0.770 and 80.4 vs. 77.3 %, p = 0.516, respectively).
  
  
  CONCLUSIONS
  LR of transverse colon cancer is feasible and safe, with similar early short-term outcomes when compared to OR. Larger prospective comparative studies with long-term follow-up are needed to assess the oncological equivalence of the two approaches.
authors.affiliation: Digestive and Colorectal Surgical Department, Città della Salute e della Scienza di Torino Hospital, Centre of Minimal Invasive Surgery, University of Turin, Corso A. M. Dogliotti, 14, 10126, Turin, Italy, mistrangelo@katamail.com.
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Mistrangelo
authors.forename: Marco Ettore
authors.initials: ME
authors.lastname: Allaix
authors.forename: Paola
authors.initials: P
authors.lastname: Cassoni
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Giraudo
authors.forename: Simone
authors.initials: S
authors.lastname: Arolfo
authors.forename: Mario
authors.initials: M
authors.lastname: Morino
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016063:Blood Loss, Surgical; D003082:Colectomy / Q000379:methods*; D044684:Colon, Transverse / Q000601:surgery*; D003110:Colonic Neoplasms / Q000601:surgery*; D061887:Conversion to Open Surgery; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D010535:Laparoscopy; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D020127:Recovery of Function; D012189:Retrospective Studies