title: A gain-of-function mutation in TRPV3 causes focal palmoplantar keratoderma in a Chinese family.
authors.affiliation: Institute of Medical Systems Biology, Guangdong Medical College, Dongguan, China; Institute for Systems Biology, Seattle, Washington, USA; Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, China; These authors contributed equally to this work.. Electronic address: dr.hyq@hotmail.com.
authors.forename: Yuqing
authors.initials: Y
authors.lastname: He
authors.affiliation: Department of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, China; These authors contributed equally to this work.
authors.forename: Kang
authors.initials: K
authors.lastname: Zeng
authors.affiliation: Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, China; These authors contributed equally to this work.
authors.forename: Xibao
authors.initials: X
authors.lastname: Zhang
authors.affiliation: School of Bioscience & Bioengineering, South China University of Technology, Guangzhou, China.
authors.forename: Qiaolin
authors.initials: Q
authors.lastname: Chen
authors.affiliation: Department of Dermatology, Guangzhou First Municipal People's Hospital, Guangzhou, China.
authors.forename: Jiang
authors.initials: J
authors.lastname: Wu
authors.affiliation: Institute for Systems Biology, Seattle, Washington, USA.
authors.forename: Hong
authors.initials: H
authors.lastname: Li
authors.affiliation: Institute for Systems Biology, Seattle, Washington, USA.
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Institute for Systems Biology, Seattle, Washington, USA.
authors.forename: Gustavo
authors.initials: G
authors.lastname: Glusman
authors.affiliation: Institute for Systems Biology, Seattle, Washington, USA.
authors.forename: Jared
authors.initials: J
authors.lastname: Roach
authors.affiliation: Pacific Northwest Diabetes Research Institute, Seattle, Washington, USA.
authors.forename: Alton
authors.initials: A
authors.lastname: Etheridge
authors.affiliation: Institute for Systems Biology, Seattle, Washington, USA.
authors.forename: Shizhen
authors.initials: S
authors.lastname: Qing
authors.affiliation: Institute for Systems Biology, Seattle, Washington, USA.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Tian
authors.affiliation: Institute for Systems Biology, Seattle, Washington, USA.
authors.forename: Inyoul
authors.initials: I
authors.lastname: Lee
authors.affiliation: Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Tian
authors.affiliation: School of Bioscience & Bioengineering, South China University of Technology, Guangzhou, China.
authors.forename: Xiaoning
authors.initials: X
authors.lastname: Wang
authors.affiliation: Institute of Medical Systems Biology, Guangdong Medical College, Dongguan, China.
authors.forename: Zhihua
authors.initials: Z
authors.lastname: Wu
authors.affiliation: Institute for Systems Biology, Seattle, Washington, USA.
authors.forename: Leroy
authors.initials: L
authors.lastname: Hood
authors.affiliation: Institute of Medical Systems Biology, Guangdong Medical College, Dongguan, China.
authors.forename: Yuanlin
authors.initials: Y
authors.lastname: Ding
authors.affiliation: Institute for Systems Biology, Seattle, Washington, USA. Electronic address: kwang@systemsbiology.org.
authors.forename: Kai
authors.initials: K
authors.lastname: Wang
mesh_terms: D000328:Adult; D044466:Asian People / Q000235:genetics*; D005190:Family; D006801:Humans; D015776:Keratoderma, Palmoplantar, Diffuse / Q000235:genetics* / Q000473:pathology; D008297:Male; D009154:Mutation / Q000235:genetics*; D010212:Papilloma / Q000235:genetics* / Q000473:pathology; D010641:Phenotype; D012867:Skin / Q000473:pathology; D050916:TRPV Cation Channels / Q000235:genetics*
chemical_list: D050916:TRPV Cation Channels; C459445:TRPV3 protein, human