title: A retrospective analysis of pregnancy outcomes after kidney transplantation in a single center.
abstract: BACKGROUND
  We reported pregnancy outcomes after kidney transplantation in a single transplant center.
  
  
  METHODS
  We reviewed the perinatal outcomes of female kidney transplant patients of reproductive age (18-40 years) from 1987 to 2011.
  
  
  RESULTS
  A total of 246 patients were reviewed. Of these, 43 women registered a pregnancy following kidney transplantation. The mean patient age was 31.3 ± 4.2 years (range 24-40). The mean transplant-conception interval was 35.9 ± 12.6 months (range 24-120); 9 patients had a cadaveric allograft. The human leukocyte antigen match was ≥3/6 for 34 patients. The rate of live births was 29/43 (67.4%), miscarriage 10/43 (23.2%), preterm delivery 7/29 (24.1%), preeclampsia 5/29 (17.2%), and intrauterine growth retardation 2/29 (6.9%). Overall, 3/29 patients (10.3%) received a blood transfusion during pregnancy due to persistent symptomatic anemia, despite iron replacement and erythropoietin therapy; 24 patients (82%) had a cesarean section delivery; 3 patients had kidney rejection during pregnancy, with 2 occurring during the 6th postpartum month.
  
  
  CONCLUSIONS
  Pregnancy should be considered a high risk in renal transplant recipients, necessitating close follow-up.
authors.affiliation: Department of Obstetrics and Gynecology, Akdeniz University School of Medicine, Antalya, Turkey.
authors.forename: Munire
authors.initials: M
authors.lastname: Erman Akar
authors.forename: Murat
authors.initials: M
authors.lastname: Ozekinci
authors.forename: Cem
authors.initials: C
authors.lastname: Sanhal
authors.forename: Nilgun
authors.initials: N
authors.lastname: Kececioglu
authors.forename: Inanc
authors.initials: I
authors.lastname: Mendilcioglu
authors.forename: Yesim
authors.initials: Y
authors.lastname: Senol
authors.forename: Kerem
authors.initials: K
authors.lastname: Dirican
authors.forename: Huseyin
authors.initials: H
authors.lastname: Kocak
authors.forename: Ayhan
authors.initials: A
authors.lastname: Dinckan
authors.forename: Gultekin
authors.initials: G
authors.lastname: Suleymanlar
mesh_terms: D000022:Abortion, Spontaneous / Q000453:epidemiology; D000328:Adult; D001724:Birth Weight; D001803:Blood Transfusion / Q000706:statistics & numerical data; D002585:Cesarean Section / Q000706:statistics & numerical data; D005260:Female; D005317:Fetal Growth Retardation / Q000453:epidemiology; D005865:Gestational Age; D006084:Graft Rejection / Q000453:epidemiology; D006801:Humans; D007165:Immunosuppression Therapy; D007231:Infant, Newborn; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000601:surgery; D016030:Kidney Transplantation; D050498:Live Birth / Q000453:epidemiology; D010298:Parity; D011225:Pre-Eclampsia / Q000453:epidemiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology; D011256:Pregnancy Outcome / Q000453:epidemiology; D018566:Pregnancy, High-Risk; D047928:Premature Birth / Q000453:epidemiology; D012189:Retrospective Studies