title: The associations between polymorphisms in the CD36 gene, fat oxidation and cardiovascular disease risk factors in a young adult Australian population: a pilot study.
abstract: Our pilot study in a young adult Australian cohort aimed to investigate potential associations between CD36 polymorphisms (rs1527479 and rs1984112), fat oxidation and cardiovascular disease risk. CD36 genotype was associated with fat oxidation during sub-maximal exercise, resting heart rate and blood pressure, indicating increased chronic disease risk in this otherwise healthy cohort.
authors.affiliation: Exercise Health and Performance Faculty Research Group, Faculty of Health Sciences, University of Sydney, Lidcombe, NSW, Australia. Electronic address: ajay5611@uni.sydney.edu.au.
authors.forename: Avindra F
authors.initials: AF
authors.lastname: Jayewardene
authors.affiliation: Exercise Health and Performance Faculty Research Group, Faculty of Health Sciences, University of Sydney, Lidcombe, NSW, Australia.
authors.forename: Tom
authors.initials: T
authors.lastname: Gwinn
authors.affiliation: School of Molecular Biosciences, Faculty of Science, University of Sydney, Camperdown, NSW, Australia.
authors.forename: Dale P
authors.initials: DP
authors.lastname: Hancock
authors.affiliation: Exercise Health and Performance Faculty Research Group, Faculty of Health Sciences, University of Sydney, Lidcombe, NSW, Australia.
authors.forename: Yorgi
authors.initials: Y
authors.lastname: Mavros
authors.affiliation: Exercise Health and Performance Faculty Research Group, Faculty of Health Sciences, University of Sydney, Lidcombe, NSW, Australia.
authors.forename: Kieron B
authors.initials: KB
authors.lastname: Rooney
mesh_terms: D000273:Adipose Tissue / Q000502:physiology*; D000293:Adolescent; D000328:Adult; D001315:Australia; D018955:CD36 Antigens / Q000235:genetics*; D002318:Cardiovascular Diseases / Q000235:genetics*; D015331:Cohort Studies; D015444:Exercise / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D010084:Oxidation-Reduction; D010865:Pilot Projects; D011110:Polymorphism, Genetic / Q000235:genetics*; D012307:Risk Factors; D055815:Young Adult
chemical_list: D018955:CD36 Antigens
keywords: Blood pressure; Fatty acid translocase; Heart rate; Lipid oxidation; SNP