title: Transcatheter tricuspid valve implantation: a multicentre French study.
abstract: BACKGROUND
  Transcatheter valve-in-valve (VIV) implantation in failing bioprosthesis is an emerging field in cardiology.
  
  
  OBJECTIVE
  To report on a French multicentre experience and a literature review of tricuspid VIV implantation.
  
  
  METHODS
  We approached different institutions and collected 10 unpublished cases; a literature review identified 71 patients, including our 10 cases. Clinical aspects and haemodynamic data are discussed.
  
  
  RESULTS
  Among our 10 unpublished cases, the reason for implantation was significant tricuspid stenosis (n = 4), significant tricuspid regurgitation (n = 1) or mixed lesion (n = 5). Implantation was performed under general anaesthesia at mean age 28 ± 17 years. The 22 mm Melody valve was implanted in seven patients; the Edwards SAPIEN valve was implanted in three patients. The procedure succeeded in all cases, despite two embolizations in the right cardiac chambers; in both cases, the valve was stabilized close to the tricuspid annulus using a self-expandable stent, before implantation of a second Edwards SAPIEN valve. Functional class improved in all but one case. Mean diastolic gradient decreased from 9 ± 2.45 mmHg to 3.65 ± 0.7 mmHg (p = 0.007); no more than trivial regurgitation was noticed. Among the published cases, the Melody valve was implanted in 41 patients, the Edwards SAPIEN valve in 29 patients and the Braile valve in one patient. Short-term results were similar for our 10 cases, but mid-term results are not yet available.
  
  
  CONCLUSIONS
  Tricuspid VIV implantation using the Melody or Edwards SAPIEN valves is a feasible and effective procedure for selected patients with failing bioprosthesis.
authors.affiliation: EA 2693, service de cardiologie infantile et congénitale, université Lille 2 Nord de France, hôpital cardiologique, CHRU de Lille, 59037 Lille cedex, France. Electronic address: francois.godart@chru-lille.fr.
authors.forename: Francois
authors.initials: F
authors.lastname: Godart
authors.affiliation: Centre chirurgical Marie-Lannelongue, Le Plessis-Robinson, France.
authors.forename: Alban-Elouen
authors.initials: AE
authors.lastname: Baruteau
authors.affiliation: Centre chirurgical Marie-Lannelongue, Le Plessis-Robinson, France.
authors.forename: Jérôme
authors.initials: J
authors.lastname: Petit
authors.affiliation: Centre chirurgical Marie-Lannelongue, Le Plessis-Robinson, France.
authors.forename: Jean-Yves
authors.initials: JY
authors.lastname: Riou
authors.affiliation: Cardiologie pédiatrique, hôpital Louis-Pradel, Lyon, France.
authors.forename: Francois
authors.initials: F
authors.lastname: Sassolas
authors.affiliation: Service de cardiologie et maladies cardiovasculaires, hôpital Gabriel-Montpied, CHU de Clermont-Ferrand, Clermont-Ferrand, France.
authors.forename: Jean R
authors.initials: JR
authors.lastname: Lusson
authors.affiliation: Cardiologie pédiatrique, hôpital de la Timone-Enfants, Marseille, France.
authors.forename: Alain
authors.initials: A
authors.lastname: Fraisse
authors.affiliation: Cardiologie infantile, université Paris Descartes, hôpital Necker Enfants-Malades, Paris, France.
authors.forename: Younes
authors.initials: Y
authors.lastname: Boudjemline
mesh_terms: D000293:Adolescent; D000328:Adult; D001705:Bioprosthesis; D006328:Cardiac Catheterization / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D002648:Child; D005260:Female; D005602:France; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D011475:Prosthesis Failure; D016896:Treatment Outcome; D014261:Tricuspid Valve / Q000503:physiopathology / Q000601:surgery*; D014262:Tricuspid Valve Insufficiency / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D014264:Tricuspid Valve Stenosis / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D055815:Young Adult
keywords: Edwards SAPIEN valve; Melody valve; Remplacement valvulaire VIV; Tricuspid; Tricuspide; VIV implantation; Valve Melody; Valve SAPIEN d’Edwards