title: The T4 molecule: function and structure.
abstract: T4 antigen bearing T lymphocytes are central immunoregulatory cells which display helperlinducer functions, proliferate in response to antigen, control suppression and release lymphokines. In this review, Angus Dalgleish describes growing evidence that these different functions are carried out by phenotypically different subpopulations of T4-positive T cells, and discusses T4 as a putative receptor for class II MHC molecules and HTLV-III.
authors.affiliation: Clinical Research Centre, Northwick Park Hospital, Harrow HAI 3UJ, and the Royal Postgraduate Medical School, Hammersmith, USA.
authors.forename: A G
authors.initials: AG
authors.lastname: Dalgleish