title: Immunotoxicology and the new biotechnology.
abstract: The use of recombinant DNA techniques, cell fusion and novel bioprocessing in the pharmaceutical industry has assisted the development of many kinds of diagnostic and therapeutic products. Some directly affect the immune system (e.g. interleukins, interferons, tumour necrosis factor, and colony stimulating factors). Others (e.g. peptides, cytokines, growth factors, H2-receptor antagonists, non-steroidal anti-inflammatory drugs and neurohormonal agents) have immunological reactivity even though they are not designed to be immune modulators. The need to define the immunotoxicological potential of these products during preclinical safety evaluation was among the topics discussed at a recent meeting.
authors.affiliation: Joy Cavagnaro is a Senior Staff Scientist at Hazleton Laboratories America, Vienna, VA 22075, USA.
authors.forename: J
authors.initials: J
authors.lastname: Cavagnaro