title: [Multimodal treatment of esophageal carcinoma].
abstract: Despite major progress in clinical diagnostics and therapy, esophageal carcinoma represents a tumor entity with limited prognosis. In case of carcinoma restricted to mucosa endoscopic resection has developed into an important therapeutic method. Surgical resection represents the standard procedure for patients with locally limited (cT1/T2, N0) and advanced carcinoma (cT3, T4, Nx). In multimodal therapy neoadjuvant treatment concepts with chemotherapy or radiochemotherapy for patients with locally advanced tumors are well established. In case of metastatic disease palliative radio- and chemotherapy represent a treatment concept, however therapy efficiency is very limited. This review reflects the current status of multimodal therapy.
authors.affiliation: Klinik für Gastroenterologie, Hepatologie und Infektiologie, Heinrich-Heine-Universität Düsseldorf.
authors.forename: D
authors.initials: D
authors.lastname: Graf
authors.affiliation: Klinik für Allgemein-, Viszeral- und Kinderchirurgie, Heinrich-Heine-Universität Düsseldorf.
authors.forename: D
authors.initials: D
authors.lastname: Vallböhmer
authors.affiliation: Klinik für Allgemein-, Viszeral- und Kinderchirurgie, Heinrich-Heine-Universität Düsseldorf.
authors.forename: W T
authors.initials: WT
authors.lastname: Knoefel
authors.affiliation: Klinik und Poliklinik für Strahlentherapie und Radioonkologie, Heinrich-Heine-Universität Düsseldorf.
authors.forename: W
authors.initials: W
authors.lastname: Budach
authors.affiliation: Klinik für Gastroenterologie, Hepatologie und Infektiologie, Heinrich-Heine-Universität Düsseldorf.
authors.forename: D
authors.initials: D
authors.lastname: Häussinger
mesh_terms: D059186:Chemoradiotherapy, Adjuvant / Q000379:methods*; D003131:Combined Modality Therapy / Q000379:methods; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D016629:Esophagectomy / Q000379:methods*; D004945:Esophagoscopy / Q000379:methods*; D019317:Evidence-Based Medicine; D006801:Humans; D010166:Palliative Care / Q000379:methods*; D016896:Treatment Outcome