title: Core needle biopsy is a safe and accurate initial diagnostic procedure for suspected lymphoma.
abstract: BACKGROUND
  Excisional biopsy is currently recommended for the analysis of lymphadenopathy suspicious for lymphoma. This study aims to evaluate the efficacy and safety of image-guided core needle biopsy (IGCNB) for the diagnosis of lymphoma using a standard protocol for tissue acquisition and analysis.
  
  
  METHODS
  All IGCNBs from 2008 to 2014 performed under the study protocol were included in analysis. Demographics, pathology results, additional studies, and follow-up information were recorded.
  
  
  RESULTS
  Seventy-three IGCNBs were performed in 71 consecutive patients. Lymphoma was diagnosed in 37 patients (51%). All 37 patients (100%) were subtyped and treated based on IGCNB results. The remaining 36 IGCNBs in 34 patients did not have subsequent diagnosis of lymphoma in a mean follow-up of 15 months (range, 0 to 54 months). There were no complications.
  
  
  CONCLUSIONS
  IGCNB performed under a standard protocol is effective and safe and should be considered as an initial diagnostic tool for the evaluation of lymphadenopathy suspicious for lymphoma.
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Harbor-UCLA Medical Center, 1000 West Carson Box 25, Torrance, CA 90502, USA.
authors.forename: Brian M
authors.initials: BM
authors.lastname: Nguyen
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Harbor-UCLA Medical Center, 1000 West Carson Box 25, Torrance, CA 90502, USA.
authors.forename: Chelsea
authors.initials: C
authors.lastname: Halprin
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Harbor-UCLA Medical Center, 1000 West Carson Box 25, Torrance, CA 90502, USA.
authors.forename: Yuliya
authors.initials: Y
authors.lastname: Olimpiadi
authors.affiliation: Department of Pathology, Harbor-UCLA Medical Center, 1000 West Carson Box 25, Torrance, CA 90502, USA.
authors.forename: Peter
authors.initials: P
authors.lastname: Traum
authors.affiliation: Division of Hematology and Medical Oncology, Department of Medicine, Harbor-UCLA Medical Center, 1000 West Carson Box 25, Torrance, CA 90502, USA.
authors.forename: James J
authors.initials: JJ
authors.lastname: Yeh
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Harbor-UCLA Medical Center, 1000 West Carson Box 25, Torrance, CA 90502, USA. Electronic address: cdauphine@dhs.lacounty.gov.
authors.forename: Christine
authors.initials: C
authors.lastname: Dauphine
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D062005:Biopsy, Large-Core Needle; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D018084:Ultrasonography, Interventional
keywords: Core biopsy; Core needle biopsy; Diagnosis; Lymphoma; Ultrasound; Ultrasound-guided biopsy