title: Rare Disease: Lobar Holoprosencephaly With a Median Cleft Lip-Case Report.
abstract: Holoprosencephaly is a complex malformation of the brain associated with the median facial defects. Variability of the clinical picture is the characteristic of this anomaly. In most cases, the degree of severity of the facial anomaly correlates with the degree of damage to the brain. This article aims to present a rare case of child with a milder form of brain anomaly combined with a severe form of facial anomaly. The article also presents the application of a feeding stimulator to improve the child's quality of life. The anomaly was diagnosed by postnatal sonography of the brain, magnetic resonance imaging of the endocranium, and three-dimensional computed tomography of the craniofacial skeleton.
authors.forename: Julija
authors.initials: J
authors.lastname: Radojicic
authors.forename: Tatjana
authors.initials: T
authors.lastname: Tanic
authors.forename: Zoran
authors.initials: Z
authors.lastname: Pesic
authors.forename: Nebojsa
authors.initials: N
authors.lastname: Jovic
authors.forename: Tatjana
authors.initials: T
authors.lastname: Cutovic
authors.forename: Gordana
authors.initials: G
authors.lastname: Filipovic
mesh_terms: D002971:Cleft Lip / Q000000981:diagnostic imaging*; D002972:Cleft Palate / Q000000981:diagnostic imaging*; D005260:Female; D016142:Holoprosencephaly / Q000000981:diagnostic imaging*; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D035583:Rare Diseases / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
keywords: agenesis of premaxilla; holoprosencephaly; hypotelorism; median cleft lip