title: Novel anti-Helicobacter pylori therapies.
abstract: Helicobacter pylori is a ubiquitous gastropathogen infecting more than half of the world population. It is associated with dyspepsia, gastritis, gastroduodenal ulcers, mucus-associated lymphoid tissue lymphoma and gastric carcinoma. Current recommended therapy does not eradicate infection in all treated cases and at least 20% post-treatment patients continue to suffer. Salvage therapy helps some of these nonresponders, but resistance to available antibiotics is mounting. Hence, its treatment still remains a daunting task for the practicing physician. Novel medications with improved efficacy and tolerability and with less chances of resistance are required. The present review attempts to discuss the newer patents in this field, which demonstrate a promising future role in the management of H. pylori infection and its consequent problems.
authors.forename: Sukhbir K
authors.initials: SK
authors.lastname: Shahid
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000627:therapeutic use*; D015195:Drug Design; D004359:Drug Therapy, Combination; D016481:Helicobacter Infections / Q000188:drug therapy* / Q000382:microbiology* / Q000517:prevention & control; D016480:Helicobacter pylori; D010330:Patents as Topic; D008517:Phytotherapy; D054328:Proton Pump Inhibitors / Q000737:chemistry / Q000627:therapeutic use*; D016879:Salvage Therapy; D014612:Vaccines
chemical_list: D000900:Anti-Bacterial Agents; D054328:Proton Pump Inhibitors; D014612:Vaccines