title: Isotype-specific regulation of the IgE response by IgE-binding factors.
abstract: The IgE response is regulated by antigen-speck helper and suppressor T cells. Here Kimishige Ishizaka and his colleagues discuss recent work which indicates that soluble IgE-binding T-cell factors provide an additional, isotypespecific level of control on the antibody response.
authors.affiliation: The John Hopkins University School of Medicine, Departments of Medicine and Immunology, The Good Samaritan Hospital, Baltimore, MD 21239, USA.
authors.forename: K
authors.initials: K
authors.lastname: Ishizaka
authors.forename: J
authors.initials: J
authors.lastname: Yodoi
authors.forename: M
authors.initials: M
authors.lastname: Suemura
authors.forename: M
authors.initials: M
authors.lastname: Hirashima