title: Fifty-five-year-old man with chronic yeast infections.
abstract: As immunologists, we are frequently asked to evaluate patients with recurrent infections. These infections can provide us with clues regarding what pathways might be aberrant in a given patient, e.g., specific pyogenic bacteria with Toll-like receptor problems, atypical mycobacteria with interferon gamma receptor autoantibodies, and Candida/staphylococcal infections with cellular immune abnormalities. We present a 55-year-old man who presented to our immunology clinic with onychodystrophy of the toenails and fingernails and recurrent oral-esophageal candidiasis. The differential diagnosis for recurrent yeast infections is complex and includes usual suspects as well as some that are not as straightforward.
authors.affiliation: Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
authors.forename: Joshua L
authors.initials: JL
authors.lastname: Kennedy
authors.forename: Nikhila
authors.initials: N
authors.lastname: Schroeder
authors.forename: Thamiris
authors.initials: T
authors.lastname: Palacios
authors.forename: Lindsey B
authors.initials: LB
authors.lastname: Rosen
authors.forename: Bianca
authors.initials: B
authors.lastname: Martinez
authors.forename: Sarah
authors.initials: S
authors.lastname: Browne
authors.forename: Larry
authors.initials: L
authors.lastname: Borish
mesh_terms: D002175:Candida; D002177:Candidiasis / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology*; D002178:Candidiasis, Chronic Mucocutaneous / Q000150:complications / Q000175:diagnosis / Q000382:microbiology; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D013945:Thymoma / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome