title: Total lymphoid irradiation.
abstract: The delivery of ionizing radiation to lymph nodes, thymus and spleen while non-lymphoid organs are shielded has profoundly immunosuppressive effects that may have value in transplantation and the treatment of autoimmune disorders. Here Shimon Slavin reviews what is known of the cellular consequences of total lymphoid irradiation in animals and discusses the results of its use in various clinical immunosuppressive treatment regimens.
authors.affiliation: Department of Bone Marrow Transplantation and Immunobiology Research, Hadassah University Hospital, 91120 Jerusalem, Israel.
authors.forename: S
authors.initials: S
authors.lastname: Slavin