title: Possible target antigens in autoimmune endocrine disease.
abstract: Insulin is most familiar in its circulatingform, binding to appropriately equipped target cells which are remote from the site of insulin synthesis, the pancreatic islet cells. Here David Kaplan describes recent observations that insulin and perhaps other hormones are also detectable as surface membrane antigens on the cells that secrete them, and discusses the implications of these findings for the study of autoimmune disease.
authors.affiliation: Department of Pathology, Washington University School of Medicine, St Louis, MO 63110, USA.
authors.forename: D R
authors.initials: DR
authors.lastname: Kaplan