title: Interactions of CT DNA with hexagonal NaYF4 co-doped with Yb(3+)/Tm(3+) upconversion particles.
abstract: The interaction of UCPs with CT DNA are studied in detail by zeta potential, Energy dispersive spectrometer (EDS) spectroscopy, Thermogravimetric (TGA) analysis, DNA melting determination and various spectroscopic techniques including Ultraviolet-Visible (UV-Vis) absorption, fluorescence, circular dichroism (CD), Fourier transform infrared (FTIR) and Raman spectroscopy. The results indicate that CT DNA can assemble on the surface of UCPs mainly by relative stronger hydrophobic force and electrostatic binding, and the predominant interaction site is the deoxyribosyl phosphate backbone of CT DNA. Moreover, after interacting with UCPs, the double helix structure of DNA is undamaged.
authors.affiliation: College of Chemistry and Materials Science, Analysis and Testing Centre, Jiangsu Key Laboratory of Biofunctional Materials, Jiangsu Collaborative Innovation Centre of Biomedical Functional Materials, Key Laboratory of Applied Photochemistry, Nanjing Normal University, China.
authors.forename: Xiuxue
authors.initials: X
authors.lastname: Yuan
authors.affiliation: College of Chemistry and Materials Science, Analysis and Testing Centre, Jiangsu Key Laboratory of Biofunctional Materials, Jiangsu Collaborative Innovation Centre of Biomedical Functional Materials, Key Laboratory of Applied Photochemistry, Nanjing Normal University, China.
authors.forename: Wenchao
authors.initials: W
authors.lastname: Gu
authors.affiliation: College of Chemistry and Materials Science, Analysis and Testing Centre, Jiangsu Key Laboratory of Biofunctional Materials, Jiangsu Collaborative Innovation Centre of Biomedical Functional Materials, Key Laboratory of Applied Photochemistry, Nanjing Normal University, China.
authors.forename: Mengsi
authors.initials: M
authors.lastname: Xiao
authors.affiliation: College of Chemistry and Materials Science, Analysis and Testing Centre, Jiangsu Key Laboratory of Biofunctional Materials, Jiangsu Collaborative Innovation Centre of Biomedical Functional Materials, Key Laboratory of Applied Photochemistry, Nanjing Normal University, China.
authors.forename: Wenli
authors.initials: W
authors.lastname: Xie
authors.affiliation: College of Chemistry and Materials Science, Analysis and Testing Centre, Jiangsu Key Laboratory of Biofunctional Materials, Jiangsu Collaborative Innovation Centre of Biomedical Functional Materials, Key Laboratory of Applied Photochemistry, Nanjing Normal University, China.
authors.forename: Shaohua
authors.initials: S
authors.lastname: Wei
authors.affiliation: College of Chemistry and Materials Science, Analysis and Testing Centre, Jiangsu Key Laboratory of Biofunctional Materials, Jiangsu Collaborative Innovation Centre of Biomedical Functional Materials, Key Laboratory of Applied Photochemistry, Nanjing Normal University, China. Electronic address: zhoulin@njnu.edu.cn.
authors.forename: Lin
authors.initials: L
authors.lastname: Zhou
authors.affiliation: College of Chemistry and Materials Science, Analysis and Testing Centre, Jiangsu Key Laboratory of Biofunctional Materials, Jiangsu Collaborative Innovation Centre of Biomedical Functional Materials, Key Laboratory of Applied Photochemistry, Nanjing Normal University, China. Electronic address: zhoujiahong@njnu.edu.cn.
authors.forename: Jiahong
authors.initials: J
authors.lastname: Zhou
authors.affiliation: College of Chemistry and Materials Science, Analysis and Testing Centre, Jiangsu Key Laboratory of Biofunctional Materials, Jiangsu Collaborative Innovation Centre of Biomedical Functional Materials, Key Laboratory of Applied Photochemistry, Nanjing Normal University, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Shen
mesh_terms: D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry*; D005459:Fluorides / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013059:Spectrum Analysis, Raman; D013932:Thulium / Q000737:chemistry*; D015018:Ytterbium / Q000737:chemistry*; D015019:Yttrium / Q000737:chemistry*
chemical_list: C525362:sodium yttriumtetrafluoride; D015019:Yttrium; D013932:Thulium; D004247:DNA; D015018:Ytterbium; D005459:Fluorides
keywords: CT DNA; Complex; Deoxyribosyl phosphate backbone; Electrostatic binding; Hydrophobic force; UCPs