title: A new diketopyrrolopyrrole-based probe for sensitive and selective detection of sulfite in aqueous solution.
abstract: A new probe was synthesized by incorporating an α,β-unsaturated ketone to a diketopyrrolopyrrole fluorophore. The probe had exhibited a selective and sensitive response to the sulfite against other thirteen anions and biothiols (Cys, Hcy and GSH), through the nucleophilic addition of sulfite to the alkene of probe with the detection limit of 0.1 μM in HEPES (10 mM, pH 7.4) THF/H2O (1:1, v/v). Meanwhile, it could be easily observed that the probe for sulfite changed from pink to colorless by the naked eye, and from pink to blue under UV lamp after the sulfite was added for 20 min. The NMR and Mass spectral analysis demonstrated the expected addition of sulfite to the C=C bonds.
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China. Electronic address: chm_yangxf@ujn.edu.cn.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Yang
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Cui
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China.
authors.forename: Yexin
authors.initials: Y
authors.lastname: Li
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China.
authors.forename: Luyi
authors.initials: L
authors.lastname: Zheng
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China.
authors.forename: Lijun
authors.initials: L
authors.lastname: Xie
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China.
authors.forename: Rui
authors.initials: R
authors.lastname: Ning
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Liu
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China.
authors.forename: Junling
authors.initials: J
authors.lastname: Lu
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China.
authors.forename: Gege
authors.initials: G
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China.
authors.forename: Chunxiang
authors.initials: C
authors.lastname: Liu
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China. Electronic address: chm_zhanggy@ujn.edu.cn.
authors.forename: Guangyou
authors.initials: G
authors.lastname: Zhang
mesh_terms: D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry*; D013447:Sulfites / Q000032:analysis*
chemical_list: D005456:Fluorescent Dyes; D011758:Pyrroles; D013447:Sulfites
keywords: Aqueous solution; Diketopyrrolopyrrole; Fluorescence; Sulfite anion detection