title: Primary esophageal Burkitt's lymphoma: a rare case report and review of literature.
abstract: Esophageal lymphoma is a rare condition, accounting for less than 1% of all gastrointestinal lymphomas. Primary extra nodal esophageal lymphoma constitutes less than 0.2% cases of the total esophageal lymphomas. The definition of primary GI lymphoma has differed among authors. The etiology of the disease is unknown, with the role of Epstein-Barr virus being controversial. The common symptoms of patients with esophageal lymphoma include dysphasia, odynophagia, weight loss, chest pain or present as a result of complications. Burkitt's lymphoma is one of the fastest growing human malignancies, with a 100% replication rate. Endemic, sporadic (non-endemic) and immunodeficient variants have been recognized. The diagnosis of Burkitt's lymphoma relies on morphologic findings, immunophenotyping results, and cytogenetic features. Burkitt's lymphoma is usually treated with LMB-96 protocol depending on the risk stratification. We present a case of primary esophageal Burkitt's lymphoma, which has been successfully treated with LMB-96 protocol. An extensive review of literature did not reveal a single case of esophageal Burkitt's lymphoma. To the best of our knowledge this is the first case report in the world literature with diagnosis of primary esophageal Burkitt's lymphoma.
authors.affiliation: Department of Medical and Pediatric Oncology, GCRI, Ahmedabad, Gujarat, India.
authors.forename: Irappa
authors.initials: I
authors.lastname: Madabhavi
authors.affiliation: Department of Medical and Pediatric Oncology, GCRI, Ahmedabad, Gujarat, India.
authors.forename: Apurva
authors.initials: A
authors.lastname: Patel
authors.affiliation: Department of Radiation Oncology, Swami Rama Cancer, Hospital & Research Institute, Government Medical College- Haldwani, Nainithal, Uttarakhand, India.
authors.forename: Swaroop
authors.initials: S
authors.lastname: Revannasiddaiah
authors.affiliation: Department of Medical and Pediatric Oncology, GCRI, Ahmedabad, Gujarat, India.
authors.forename: Mukesh
authors.initials: M
authors.lastname: Choudhary
authors.affiliation: Department of Medical and Pediatric Oncology, GCRI, Ahmedabad, Gujarat, India.
authors.forename: Asha
authors.initials: A
authors.lastname: Anand
authors.affiliation: Department of Medical and Pediatric Oncology, GCRI, Ahmedabad, Gujarat, India.
authors.forename: Priyanka
authors.initials: P
authors.lastname: Das
authors.affiliation: Department of Medical and Pediatric Oncology, GCRI, Ahmedabad, Gujarat, India.
authors.forename: Harsha
authors.initials: H
authors.lastname: Panchal
authors.affiliation: Department of Medical and Pediatric Oncology, GCRI, Ahmedabad, Gujarat, India.
authors.forename: Sonia
authors.initials: S
authors.lastname: Parikh
authors.affiliation: Department of Radiology, GCRI, Ahmedabad, Gujarat, India.
authors.forename: Suhas
authors.initials: S
authors.lastname: Aagre
authors.affiliation: Department of Medical and Pediatric Oncology, GCRI, Ahmedabad, Gujarat, India.
authors.forename: Vishalkumar
authors.initials: V
authors.lastname: Bhardava
authors.affiliation: Department of Medical and Pediatric Oncology, GCRI, Ahmedabad, Gujarat, India.
authors.forename: Avinash
authors.initials: A
authors.lastname: Talele
keywords: Burkitt’s lymphoma (BL); COPADM; Diffuse large B-cell lymphoma (DLBCL); Gastrointestinal (GI) lymphoma; Non-Hodgkin’s Lymphoma (NHL)