title: Acute exercise increases oxygenated and deoxygenated hemoglobin in the prefrontal cortex.
abstract: Both acute and chronic exercise is consistently associated with a number of benefits to physical and mental health, including cardiovascular function, body weight, mood, and cognition. Near-infrared spectroscopy is an ideal method to measure changes in oxygenated and deoxygenated hemoglobin (O2Hb and dHb) levels in the prefrontal cortex (PFC) during exercise, to better understand the locus of such changes in affective and cognitive processes. The present study tracked time-dependent changes in O2Hb and dHb levels in the PFC as a function of parametrically manipulated target exercise intensity. Near-infrared spectroscopy was conducted as regular exercisers completed a 30-min bout of exercise with one of three target intensities: 52% (low condition), 68% (moderate condition), or 84% (high condition) of age-adjusted maximum heart rate. Heart rate data confirmed that the participants reached their goal intensities immediately, after 10 min, or after 20 min, respectively. Data showed that O2Hb and dHb levels in the PFC increased as a function of both exercise load and duration. An 84%>68%>52% difference was evident after 18 min of cycling for O2Hb and after 23 min of cycling for dHb. The present results add to the growing body of literature showing that at submaximal levels, increasing exercise intensities reliably promote prefrontal cerebral oxygenation.
authors.affiliation: aDepartment of Psychology, Tufts University, Medford bCognitive Science Team, US Army NSRDEC, Natick, Massachusetts cDepartment of Psychology, Stanford University, Stanford, California, USA.
authors.forename: Grace E
authors.initials: GE
authors.lastname: Giles
authors.forename: Tad T
authors.initials: TT
authors.lastname: Brunyé
authors.forename: Marianna D
authors.initials: MD
authors.lastname: Eddy
authors.forename: Caroline R
authors.initials: CR
authors.lastname: Mahoney
authors.forename: Stephanie A
authors.initials: SA
authors.lastname: Gagnon
authors.forename: Holly A
authors.initials: HA
authors.lastname: Taylor
authors.forename: Robin B
authors.initials: RB
authors.lastname: Kanarek
mesh_terms: D000293:Adolescent; D000328:Adult; D001931:Brain Mapping; D015444:Exercise / Q000502:physiology*; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D010101:Oxygen Consumption; D005082:Physical Exertion; D017397:Prefrontal Cortex / Q000098:blood supply* / Q000378:metabolism*; D019265:Spectroscopy, Near-Infrared; D055815:Young Adult