title: Bochum ultrasound score versus clinical and electrophysiological parameters in distinguishing acute-onset chronic from acute inflammatory demyelinating polyneuropathy.
abstract: BACKGROUND
  The aim of this study was to evaluate whether a nerve ultrasound score (Bochum ultrasound score, BUS), clinical, and electrophysiological parameters could distinguish subacute chronic (CIDP) from acute inflammatory demyelinating polyneuropathy (AIDP).
  
  
  METHODS
  Phase 1: The charts of 35 patients with polyradiculoneuropathy were evaluated retrospectively regarding BUS, clinical, and electrophysiological parameters (A-waves, sural nerve sparing pattern, sensory ratio>1). Phase 2: All parameters were evaluated prospectively in 10 patients with subacute polyradiculoneuropathy.
  
  
  RESULTS
  Phase 1: A sum score of ≥2 points in BUS and the presence of sensory symptoms were significantly more frequent in the subacute CIDP group than in the AIDP group (P<0.001).The electrophysiological parameters showed no significant changes between the 2 groups. Phase 2: BUS (83.3%; 100%;), sensory symptoms (100%; 75%), absence of autonomic nervous system dysfunction (83.3%; 75%), or bulbar palsy (83.3%; 50%) showed the best sensitivity and specificity in distinguishing subacute CIDP from AIDP.
  
  
  CONCLUSIONS
  BUS is a useful diagnostic tool for distinguishing subacute CIDP from AIDP.
authors.affiliation: Department of Neurology, St. Josef Hospital, Ruhr-University of Bochum, Gudrunstr. 56, 44791, Bochum, Germany.
authors.forename: Antonios
authors.initials: A
authors.lastname: Kerasnoudis
authors.affiliation: Department of Neurology, St. Josef Hospital, Ruhr-University of Bochum, Gudrunstr. 56, 44791, Bochum, Germany.
authors.forename: Kallia
authors.initials: K
authors.lastname: Pitarokoili
authors.affiliation: Department of Neurology, St. Josef Hospital, Ruhr-University of Bochum, Gudrunstr. 56, 44791, Bochum, Germany.
authors.forename: Volker
authors.initials: V
authors.lastname: Behrendt
authors.affiliation: Department of Neurology, St. Josef Hospital, Ruhr-University of Bochum, Gudrunstr. 56, 44791, Bochum, Germany.
authors.forename: Ralf
authors.initials: R
authors.lastname: Gold
authors.affiliation: Department of Neurology, St. Josef Hospital, Ruhr-University of Bochum, Gudrunstr. 56, 44791, Bochum, Germany.
authors.forename: Min-Suk
authors.initials: MS
authors.lastname: Yoon
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000328:Adult; D000368:Aged; D004558:Electric Stimulation; D005260:Female; D020275:Guillain-Barre Syndrome / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000503:physiopathology; D009431:Neural Conduction / Q000502:physiology; D010525:Peripheral Nerves / Q000000981:diagnostic imaging / Q000503:physiopathology; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000503:physiopathology*; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D014463:Ultrasonography
keywords: Bochum Ultrasound Score; Nerve ultrasound; acute inflammatory demyelinating polyneuropathy; chronic inflammatory demyelinating polyneuropathy; sural sparing