title: The efficacy of flavonoid antioxidant from chocolate: bean extract: prevention of myocyte damage caused by reperfusion injury in predominantly anaerobic sports.
abstract: Background : Use of predominantly anaerobic energy systems such as that seen in 800-meter athlete runners disrupts mitochondrial function as an energy source. Furthermore, it produces free radical substances and causes myocyte damage. Malondialdehyde (MDA) plasma concentrations correlate with free radical levels and are therefore predictive of cell damage.
  
  
  OBJECTIVE
  To analyse the effect of flavonoid antioxidant from chocolate bean extract for prevention of lipid peroxidation of myocyte membranes caused by free radical substances in athletes partaking in predominantly anaerobic sports.
  
  
  METHODS
  The study of population consisted of 16 junior athletes who compete in 800-meter races. This was a randomized experimental study. Subjects were divided into two groups, chocolate bean extracts and placebo groups, and then practiced regularly for 14 days. All subjects were assessed on day 15. RESULTS were analysed statistically using paired t test, ANOVA and Duncan tests.
  
  
  RESULTS
  Concentrations of MDA were reduced in flavonoid group.
  
  
  CONCLUSIONS
  Flavonoid antioxidant from chocolate bean extract may prevent myocyte damage was caused by reperfusion injury.
authors.affiliation: Department of Orthopaedics and Traumatology, Faculty of Medicine Universitas Padjadjaran / Hasan Sadikin General Hospital, Bandung, Indonesia.
authors.forename: H N
authors.initials: HN
authors.lastname: Rasyid
authors.affiliation: Department of Orthopaedics and Traumatology, Faculty of Medicine Universitas Padjadjaran / Hasan Sadikin General Hospital, Bandung, Indonesia.
authors.forename: Y D
authors.initials: YD
authors.lastname: Ismiarto
authors.affiliation: Department of Orthopaedics and Traumatology, Faculty of Medicine Universitas Padjadjaran / Hasan Sadikin General Hospital, Bandung, Indonesia.
authors.forename: R
authors.initials: R
authors.lastname: Prasetia