title: In-Vitro Investigations of Nanoparticle Magnetic Thermotherapy: Adjuvant Effects and Comparison to Conventional Heating.
abstract: Thermotherapy, particularly magnetic nanoparticle hyperthermia, is a promising modality both as a direct cancer cell killing and as a radiosensitization technique for adjuvant therapy. Dextran-coated iron oxide nanoparticles were mixed with multiple tumor cell lines in solution and exposed to varying magnetic field regimes and combined with traditional external radiotherapy. Heating of cell lines by water bath in temperature patterns comparable to those achieved by nanoparticle hyperthermia was conducted to assess the relative value of nano-magnetic thermotherapy compared with conventional bulk heating techniques and data.
authors.affiliation: Dartmouth College, Thayer School of Engineering, and Dartmouth Medical School.
authors.forename: Z
authors.initials: Z
authors.lastname: Pierce
authors.affiliation: Dartmouth College, Thayer School of Engineering, and Dartmouth Medical School.
authors.forename: R
authors.initials: R
authors.lastname: Strawbridge
authors.affiliation: Dartmouth College, Thayer School of Engineering, and Dartmouth Medical School.
authors.forename: C
authors.initials: C
authors.lastname: Gaito
authors.affiliation: Dartmouth College, Thayer School of Engineering, and Dartmouth Medical School.
authors.forename: L
authors.initials: L
authors.lastname: Dulatas
authors.affiliation: Dartmouth College, Thayer School of Engineering, and Dartmouth Medical School.
authors.forename: J
authors.initials: J
authors.lastname: Tate
authors.affiliation: Dartmouth College, Thayer School of Engineering, and Dartmouth Medical School.
authors.forename: J
authors.initials: J
authors.lastname: Ogden
authors.affiliation: Dartmouth College, Thayer School of Engineering, and Dartmouth Medical School.
authors.forename: P J
authors.initials: PJ
authors.lastname: Hoopes