title: Cooperative catalysis by palladium and a chiral phosphoric acid: enantioselective amination of racemic allylic alcohols.
abstract: Cooperative catalysis by [Pd(dba)2] and the chiral phosphoric acid BA1 in combination with the phosphoramidite ligand L8 enabled the efficient enantioselective amination of racemic allylic alcohols with a variety of functionalized amines. This catalytic protocol is highly regio- and stereoselective (up to e.r. 96:4) and furnishes valuable chiral amines in almost quantitative yield.
authors.affiliation: Leibniz-Institut für Katalyse an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059 Rostock (Germany) http://www.catalysis.de.
authors.forename: Debasis
authors.initials: D
authors.lastname: Banerjee
authors.forename: Kathrin
authors.initials: K
authors.lastname: Junge
authors.forename: Matthias
authors.initials: M
authors.lastname: Beller
keywords: allylic alcohols; asymmetric amination; chiral phosphoric acids; palladium; phosphoramidite ligands