title: Instructing the instructor: tissue-resident T cells activate innate immunity.
abstract: A small number of tissue-resident memory T cells (Trm) provide potent protection against infections. Three recent studies by Ariotti et al. (2014), Schenkel et al. (2014a), and Iijima and Iwasaki (2014) report that Trm rapidly produce cytokines after infection and initiate a tissue-wide anti-viral state by instructing innate immune cells.
authors.affiliation: Department of Microbiology, University of Iowa, Iowa City, IA 52242, USA.
authors.forename: Bram
authors.initials: B
authors.lastname: Slütter
authors.affiliation: Department of Microbiology, University of Iowa, Iowa City, IA 52242, USA; Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, IA 52242, USA; Department of Pathology, University of Iowa, Iowa City, IA 52242, USA. Electronic address: john-harty@uiowa.edu.
authors.forename: John T
authors.initials: JT
authors.lastname: Harty