title: Magnesium metabolism in Huntington's chorea.
abstract: Human magnesium deficiency states are known to be associated with tremor, choreiform and athetoid movements, delirium and convulsions. In order to assess a recent report of altered magnesium metabolism in Huntington's chorea, 6 patients with the disease have been studied with complete balance studies, exchangeable magnesium studies, erythrocyte and ultrafiltrable magnesiums and 2 patients with spinal fluid magnesium determinations. Balance studies failed to suggest any abnormalities. Exchangeable magnesium28 values were within normal ranges (4.3 ± 0.7 mEq./Kg. at 24 hrs.), as were erythrocyte magnesium determinations (5.29 ± 0.42 mEq./L.). Ultrafiltrable magnesiums were normal and the 2 spinal fluids evaluated had normal magnesium values. These results are not compatible with the hypothesis of altered magnesium metabolism in Huntington's chorea.
authors.forename: John E
authors.initials: JE
authors.lastname: Jones
authors.forename: Paul C
authors.initials: PC
authors.lastname: Desper
authors.forename: Edmund B
authors.initials: EB
authors.lastname: Fink
mesh_terms: D000328:Adult; D004912:Erythrocytes / Q000737:chemistry*; D005260:Female; D006801:Humans; D006816:Huntington Disease / Q000097:blood* / Q000378:metabolism*; D008274:Magnesium / Q000032:analysis* / Q000097:blood* / Q000134:cerebrospinal fluid* / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D012016:Reference Values
chemical_list: D008274:Magnesium