title: [Diabetes in Greenland - from Alfred Bertelsen to molecular diagnostics].
abstract: Health changes in Greenland have evolved in association with rapid social changes, ageing of the population, urbanisation, changes in diet and physical activity. Two population-based studies found a notably high prevalence of diabetes (9%) and pre-diabetes (19%) among Greenland Inuit. Contrary to most other studies, the highest prevalence of diabetes and pre-diabetes was observed in the least urbanised areas, and the traditional Inuit diet was associated with a higher risk of glucose intolerance. A recent study identified a strong association of a common TBC1D4 nonsense variant with diabetes.
authors.affiliation: Steno Diabetes Center, Niels Steensensvej 2, 2820 Gentofte. E-mail: maej@steno.dk.
authors.forename: Marit Eika
authors.initials: ME
authors.lastname: Jørgensen
mesh_terms: D035843:Biomedical Research / Q000639:trends; D003920:Diabetes Mellitus / Q000453:epidemiology / Q000209:etiology / Q000235:genetics / Q000628:therapy; D004032:Diet; D015444:Exercise / Q000502:physiology; D006116:Greenland / Q000453:epidemiology; D006801:Humans; D004930:Inuit; D009765:Obesity / Q000150:complications; D012307:Risk Factors; D012423:Rural Health; D014504:Urban Health