title: CEA a thrombus CAM: CEACAM2, a twin of CEACAM1?
abstract: In this issue of Blood, Alshahrani et al demonstrate that carcinoembryonic antigen-related cell adhesion molecule 2 (CEACAM2) is expressed on platelets and negatively regulates the collagen receptor glycoprotein (GP)VI-FcRγ chain and C-type lectin-like receptor 2 (CLEC-2)-mediated platelet activation.
authors.affiliation: UNIVERSITY MEDICAL CENTER HAMBURG-EPPENDORF.
authors.forename: Andrea Kristina
authors.initials: AK
authors.lastname: Horst
mesh_terms: D000818:Animals; D015703:Antigens, CD / Q000378:metabolism*; D015815:Cell Adhesion Molecules / Q000378:metabolism*; D037181:Lectins, C-Type / Q000378:metabolism*; D010980:Platelet Membrane Glycoproteins / Q000378:metabolism*; D015398:Signal Transduction; D013927:Thrombosis / Q000378:metabolism* / Q000473:pathology*
chemical_list: D015703:Antigens, CD; C069847:CD66 antigens; C529518:CLEC-2 protein, mouse; D015815:Cell Adhesion Molecules; D037181:Lectins, C-Type; D010980:Platelet Membrane Glycoproteins; C098341:platelet membrane glycoprotein VI