title: Effects of vertical and side-alternating vibration training on fall risk factors and bone turnover in older people at risk of falls.
abstract: BACKGROUND
  whole-body vibration training may improve neuromuscular function, falls risk and bone density, but previous studies have had conflicting findings.
  
  
  OBJECTIVE
  this study aimed to evaluate the influence of vertical vibration (VV) and side-alternating vibration (SV) on musculoskeletal health in older people at risk of falls.
  
  
  METHODS
  single-blind, randomised, controlled trial comparing vibration training to sham vibration (Sham) in addition to usual care.
  
  
  METHODS
  participants were 61 older people (37 women and 24 men), aged 80.2 + 6.5 years, referred to an outpatient falls prevention service.
  
  
  METHODS
  participants were randomly assigned to VV, SV or Sham in addition to the usual falls prevention programme. Participants were requested to attend three vibration sessions per week for 12 weeks, with sessions increasing to six, 1 min bouts of vibration. Falls risk factors and neuromuscular tests were assessed, and blood samples collected for determination of bone turnover, at baseline and following the intervention.
  
  
  RESULTS
  chair stand time, timed-up-and-go time, fear of falling, NEADL index and postural sway with eyes open improved in the Sham group. There were significantly greater gains in leg power in the VV than in the Sham group and in bone formation in SV and VV compared with the Sham group. Conversely, body sway improved less in the VV than in the Sham group. Changes in falls risk factors did not differ between the groups.
  
  
  CONCLUSIONS
  whole-body vibration increased leg power and bone formation, but it did not provide any additional benefits to balance or fall risk factors beyond a falls prevention programme in older people at risk of falls.
authors.affiliation: School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK.
authors.forename: Heather
authors.initials: H
authors.lastname: Corrie
authors.affiliation: School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK.
authors.forename: Katherine
authors.initials: K
authors.lastname: Brooke-Wavell
authors.affiliation: Design School, Loughborough University, Loughborough, UK.
authors.forename: Neil J
authors.initials: NJ
authors.lastname: Mansfield
authors.affiliation: Healthcare for Older People, Nottingham University Hospitals NHS Trust, Hucknall Road, Nottingham NG5 1PB, UK.
authors.forename: Alison
authors.initials: A
authors.lastname: Cowley
authors.affiliation: Healthcare for Older People, Nottingham University Hospitals NHS Trust, Hucknall Road, Nottingham NG5 1PB, UK.
authors.forename: Robert
authors.initials: R
authors.lastname: Morris
authors.affiliation: Healthcare for Older People, Nottingham University Hospitals NHS Trust, Hucknall Road, Nottingham NG5 1PB, UK.
authors.forename: Tahir
authors.initials: T
authors.lastname: Masud
mesh_terms: D000058:Accidental Falls / Q000517:prevention & control*; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D015415:Biomarkers / Q000097:blood; D016723:Bone Remodeling; D024042:Collagen Type I / Q000097:blood; D004739:England; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D053580:Muscle Strength; D018482:Muscle, Skeletal / Q000502:physiology; D010446:Peptide Fragments / Q000097:blood; D010455:Peptides / Q000097:blood; D011347:Procollagen / Q000097:blood; D018570:Risk Assessment; D012307:Risk Factors; D016037:Single-Blind Method; D013997:Time Factors; D016896:Treatment Outcome; D014732:Vibration / Q000627:therapeutic use*
chemical_list: D015415:Biomarkers; D024042:Collagen Type I; D010446:Peptide Fragments; D010455:Peptides; D011347:Procollagen; C052929:collagen type I trimeric cross-linked peptide; C047202:procollagen Type I N-terminal peptide
keywords: bone turnover; falls; muscle function; older people; whole-body vibration