title: A naphthalimide-based fluorescence "turn-on" probe for the detection of Pb(2+) in aqueous solution and living cells.
abstract: An easily available naphthalimide-based fluorescent probe NPA for Pb(2+) detection was successfully developed. NPA exhibited an obvious fluorescence turn-on response toward Pb(2+) in aqueous solution and in living cells. Moreover, a series of model compounds were rationally designed and synthesized in order to explore the sensing mechanism and binding mode of NPA with Pb(2+) .
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, 3663 N. Zhongshan Road, Shanghai (China).
authors.forename: Hio-Ieng
authors.initials: HI
authors.lastname: Un
authors.forename: Chang-Bo
authors.initials: CB
authors.lastname: Huang
authors.forename: Junhai
authors.initials: J
authors.lastname: Huang
authors.forename: Chusen
authors.initials: C
authors.lastname: Huang
authors.forename: Ti
authors.initials: T
authors.lastname: Jia
authors.forename: Lin
authors.initials: L
authors.lastname: Xu
mesh_terms: D002470:Cell Survival; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D007854:Lead / Q000032:analysis*; D015394:Molecular Structure; D053644:Naphthalimides / Q000737:chemistry*; D012996:Solutions; D014867:Water / Q000737:chemistry
chemical_list: D005456:Fluorescent Dyes; D053644:Naphthalimides; D012996:Solutions; D014867:Water; D007854:Lead
keywords: fluorescent probes; lead ion; naphthalimide; photoinduced electron transfer; sensors