title: [Diagnostic value of determination of the blood concentrations of serotonin and high-sensitivity C-reactive protein in patients with tick-borne encephalitis].
abstract: The paper shows the informative value of changes in the serum levels of serotonin and high-sensitivity C-reactive protein in 44 patients in the acute period of tickborne encephalitis. Group 1 included 35 patients with non-paralytic neuroinfection; Group 2 comprised 9 patients with paralytic neuroinfection. The serum level of high-sensitivity C-reactive protein increased and that of serotonin decreased in relation to the form and severity of the disease at its height. The elevated level of the former and the low concentration of the latter may serve as an early predictor of the development of a severe paralytic form. Investigating their serum concentrations should be included into an examination plan for patients with acute tick-borne encephalitis.
authors.forename: O N
authors.initials: ON
authors.lastname: Sumlivaia
authors.forename: N N
authors.initials: NN
authors.lastname: Vorob'eva
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Karakulova
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000378:metabolism*; D016022:Case-Control Studies; D004669:Encephalitis Viruses, Tick-Borne / Q000472:pathogenicity* / Q000502:physiology; D004675:Encephalitis, Tick-Borne / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010243:Paralysis / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D011237:Predictive Value of Tests; D011379:Prognosis; D012701:Serotonin / Q000097:blood*; D012720:Severity of Illness Index
chemical_list: D015415:Biomarkers; D012701:Serotonin; D002097:C-Reactive Protein