title: Highly diastereo- and enantioselective copper-catalyzed propargylic alkylation of acyclic ketone enamines for the construction of two vicinal stereocenters.
abstract: The first highly diastereo- and enantioselective propargylic alkylation of acyclic ketone enamines to form vicinal tertiary stereocenters has been reported by employing copper catalysis in combination with a bulky and structurally rigid tridentate ketimine P,N,N-ligand.
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China. xiangping@dicp.ac.cn.
authors.forename: De-Yang
authors.initials: DY
authors.lastname: Zhang
authors.forename: Fu-Lin
authors.initials: FL
authors.lastname: Zhu
authors.forename: Ya-Hui
authors.initials: YH
authors.lastname: Wang
authors.forename: Xin-Hu
authors.initials: XH
authors.lastname: Hu
authors.forename: Song
authors.initials: S
authors.lastname: Chen
authors.forename: Chuan-Jin
authors.initials: CJ
authors.lastname: Hou
authors.forename: Xiang-Ping
authors.initials: XP
authors.lastname: Hu