title: Cerebral venous thrombosis-a primer for the haematologist.
abstract: Cerebral venous thrombosis (CVT) is a condition that can affect all age groups and can often be difficult to diagnose and treat. The difficulties in diagnosis are mainly due to the non-specific presenting features of CVT, which can range from isolated headache and visual or auditory problems, to serious symptoms such as hemiparesis and coma. Therefore, it can present to various specialists including general physicians, obstetricians and neurologists. In recent years, more widespread use of cerebral imaging has led to the diagnosis being made more often. Since thrombosis is the key component, haematologists are consulted in the management of these patients including for identification of a causative factor for CVT. In this regard, the pivotal International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT) has shed more light on its epidemiology and management options. This review aims to provide guidance to haematologists when faced with a patient with CVT, based on the currently available evidence.
authors.affiliation: School of Medicine, University of Manchester, Oxford Road, Manchester, UK.
authors.forename: Sofia E
authors.initials: SE
authors.lastname: Thorell
authors.affiliation: Department of Neurology, Salford Royal Hospital, Stott Lane, Salford, UK.
authors.forename: Adrian R
authors.initials: AR
authors.lastname: Parry-Jones
authors.affiliation: Department of Neurology, Salford Royal Hospital, Stott Lane, Salford, UK.
authors.forename: Martin
authors.initials: M
authors.lastname: Punter
authors.affiliation: Department of Neurology, Salford Royal Hospital, Stott Lane, Salford, UK.
authors.forename: Robert
authors.initials: R
authors.lastname: Hurford
authors.affiliation: Department of Haematology, Manchester Royal Infirmary, Oxford Road, Manchester, UK. Electronic address: jecko.thachil@cmft.nhs.uk.
authors.forename: Jecko
authors.initials: J
authors.lastname: Thachil
mesh_terms: D019468:Disease Management; D005260:Female; D006801:Humans; D020767:Intracranial Thrombosis / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D011247:Pregnancy; D012307:Risk Factors; D020246:Venous Thrombosis / Q000175:diagnosis* / Q000628:therapy*
keywords: Anticoagulation; Cerebral; Embolism; Heparin; Neurology; Sinus; Thrombosis; Vein