title: Prevalence of porcine cysticercosis in the Lake Kyoga Basin, Uganda.
abstract: BACKGROUND
  Taenia solium is a zoonotic helminth with the potential to cause life threatening epilepsy in people through the aberrant larval infection of the brain called Neurocysticercosis (NCC). The pig is the intermediate host for T. solium where the larval form, cysticercus cellulosae, normally develops after the pig eats eggs of the parasite. Humans are the definitive host where the adult tapeworm develops and are infected through the consumption of poorly cooked, infected meat. T. solium has been acknowledged by the World Health Organization (WHO), Food and Agriculture Organization (FAO) and UK Department for International Development (DFID) as being a neglected zoonotic disease, and was recently included in the WHO roadmap for control of neglected tropical diseases. This neglect encompasses a lack of epidemiological data and a lack of validated, effective control strategies being adopted. Understanding the epidemiology of this parasite in the intermediate host is the first step towards designing suitable intervention strategies for the improvement of public health. This study was undertaken to provide an accurate and up-to-date estimate for the prevalence of porcine cysticercosis in the Lake Kyoga basin.
  
  
  RESULTS
  Sera from 378 pigs were analysed with the HP10 Antigen Enzyme Linked Immunosorbant Assay (ELISA) and the prevalence was found to be 25.7% (95% confidence interval 21.0% to 30.0%). Previous sero- surveillance in this region, using the B158/B60 Ag Elisa had indicated a prevalence of 8.6% in 2005 indicating a dramatic increase in prevalence (J. Parasitol Res, Article ID 375493, 2009) within a 6 year period.
  
  
  CONCLUSIONS
  This increasing prevalence in the disease indicates to us that there is currently no effective control of this parasite and that in this region of Uganda at least; cysticercosis remains a neglected zoonotic disease.
authors.affiliation: School of Veterinary Medicine and Animal Resources, Makerere University, Kampala, Uganda. znsadhansadha@gmail.com.
authors.forename: Zachary
authors.initials: Z
authors.lastname: Nsadha
authors.forename: Lian F
authors.initials: LF
authors.lastname: Thomas
authors.forename: Eric M
authors.initials: EM
authors.lastname: Fèvre
authors.forename: George
authors.initials: G
authors.lastname: Nasinyama
authors.forename: Lonzy
authors.initials: L
authors.lastname: Ojok
authors.forename: Charles
authors.initials: C
authors.lastname: Waiswa
mesh_terms: D000818:Animals; D003551:Cysticercosis / Q000453:epidemiology / Q000662:veterinary*; D006801:Humans; D015995:Prevalence; D012307:Risk Factors; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology / Q000469:parasitology*; D041201:Taenia solium; D014454:Uganda / Q000453:epidemiology; D015047:Zoonoses