title: Rituximab-Au nanoprobes for simultaneous dark-field imaging and DAB staining of CD20 over-expressed on Raji cells.
abstract: A novel dual-modal cell immunodetection method based on both dark-field imaging and catalysis functions of gold nanoparticles has been established, where the Rituximab-Au conjugates were used as nanoprobes to label and image specifically the CD20 overexpressed on the surface of malignant lymphoma cells of Raji with high affinity.
authors.affiliation: State Key Laboratory of Bioelectronics, Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Science and Medical Engineering, Southeast University, Nanjing, P. R. China. zhangyu@seu.edu.cn.
authors.forename: Lin
authors.initials: L
authors.lastname: Fan
authors.forename: Doudou
authors.initials: D
authors.lastname: Lou
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhang
authors.forename: Ning
authors.initials: N
authors.lastname: Gu
mesh_terms: D058846:Antibodies, Monoclonal, Murine-Derived / Q000737:chemistry*; D018951:Antigens, CD20 / Q000737:chemistry*; D002460:Cell Line; D006046:Gold / Q000737:chemistry*; D006801:Humans; D053768:Metal Nanoparticles; D015335:Molecular Probes; D000069283:Rituximab
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; D018951:Antigens, CD20; D015335:Molecular Probes; D000069283:Rituximab; D006046:Gold