title: Graft-versus-host reactions: clues to the etiopathology of a spectrum of immunological diseases.
abstract: Parental strain T lymphocytes injected into adult F, mice respond to allogeneic MHC antigens and so induce the symptoms of systemic graft v. host disease (GVHD). GVHD has two forms, stimulatory and suppressive, and in each there are pathological changes which resemble those seen in a variety of human disorders of immune regulation. In this article Ernst Gleichmann and his colleagues review the pathogenesis of these disorders and their induction by GVH reactions.
authors.affiliation: Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, incorporating the Laboratory of Experimental and Clinical Immunology, University of Amsterdam, Amsterdam, The Netherlands; Division of Immunology, Medical Institute of Environmental Hygiene, D-4000, Düsseldorf 1, FRG.
authors.forename: E
authors.initials: E
authors.lastname: Gleichmann
authors.forename: S T
authors.initials: ST
authors.lastname: Pals
authors.affiliation: Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, incorporating the Laboratory of Experimental and Clinical Immunology, University of Amsterdam, Amsterdam, The Netherlands; Basel Institute for Immunology, Basel, Switzerland.
authors.forename: A G
authors.initials: AG
authors.lastname: Rolink
authors.affiliation: Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, incorporating the Laboratory of Experimental and Clinical Immunology, University of Amsterdam, Amsterdam, The Netherlands; Institute of Pathology, University of Vienna, Vienna, Austria.
authors.forename: T
authors.initials: T
authors.lastname: Radaszkiewicz
authors.affiliation: Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, incorporating the Laboratory of Experimental and Clinical Immunology, University of Amsterdam, Amsterdam, The Netherlands; Diabetes Research Institute at the University of Düsseldorf, Düsseldorf, FRG.
authors.forename: H
authors.initials: H
authors.lastname: Gleichmann