title: Mitotic kinesins: a reason to delve into kinesin-12.
abstract: The failure of kinesin-targeting cancer drugs is thought to result from functional redundancy of mitotic kinesins. A new study provides mechanistic insights into kinesin-12 that help to explain its targeting to kinetochore fibers and its ability to compensate for inhibition of kinesin-5.
authors.affiliation: Department of Biomedical Engineering, Pennsylvania State University, 229 Hallowell Building, Pennsylvania State University, University Park, PA, USA. Electronic address: wohbio@engr.psu.edu.
authors.forename: William O
authors.initials: WO
authors.lastname: Hancock
mesh_terms: D002453:Cell Cycle; D006801:Humans; D016547:Kinesins / Q000235:genetics*; D018386:Kinetochores / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism*; D008941:Spindle Apparatus / Q000378:metabolism*
chemical_list: C486567:KIF15 protein, human; D016547:Kinesins