title: Fabrication of folate bioconjugated near-infrared fluorescent silver nanoclusters for targeted in vitro and in vivo bioimaging.
abstract: Thiolpolyethyleneimine stabilized silver nanoclusters (SH-PEI-AgNCs) with intense NIR fluorescence and chemical stability were fabricated in aqueous solution. The SH-PEI-AgNCs were subsequently bioconjugated with folate for targeted in vitro and in vivo bioimaging.
authors.affiliation: Research Center for Analytical Sciences, College of Chemistry, Nankai University, 94 Weijin Road, Tianjin 300071, China. xpyan@nankai.edu.cn.
authors.forename: Yong
authors.initials: Y
authors.lastname: Wang
authors.forename: Cong
authors.initials: C
authors.lastname: Dai
authors.forename: Xiu-Ping
authors.initials: XP
authors.lastname: Yan
mesh_terms: D016475:3T3 Cells; D000818:Animals; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D003952:Diagnostic Imaging; D005453:Fluorescence; D058973:Folate Receptors, GPI-Anchored / Q000235:genetics / Q000378:metabolism; D005492:Folic Acid / Q000737:chemistry* / Q000493:pharmacokinetics / Q000494:pharmacology; D006801:Humans; D051379:Mice; D046529:Microscopy, Electron, Transmission; D049329:Nanostructures / Q000737:chemistry / Q000648:ultrastructure; D009369:Neoplasms / Q000378:metabolism; D056951:Photoelectron Spectroscopy; D011094:Polyethyleneimine / Q000737:chemistry* / Q000493:pharmacokinetics / Q000494:pharmacology; D012834:Silver / Q000737:chemistry* / Q000493:pharmacokinetics / Q000494:pharmacology; D013052:Spectrometry, X-Ray Emission; D017550:Spectroscopy, Fourier Transform Infrared; D013438:Sulfhydryl Compounds / Q000737:chemistry; D014018:Tissue Distribution
chemical_list: D058973:Folate Receptors, GPI-Anchored; D013438:Sulfhydryl Compounds; D012834:Silver; D011094:Polyethyleneimine; D005492:Folic Acid