title: [Six cases of renal collecting duct carcinoma].
abstract: We treated 6 patients with renal collecting duct carcinoma (CDC) in our hospital from December 2004 to December 2011. We compared clinico-pathological findings among all patients. The median age was 58 years (range, 37-77 years). Hematuria, back pain, and fatigue were observed in 5 patients with CDC. Five patients were pathologically diagnosed by radical nephrectomy while a patient was diagnosed by percutaneous renal biopsy without radical nephrectomy. Lymph node metastasis and distant metastasis were observed at diagnosis in 3 and 2 patients, respectively. Five of the 6 patients received systemic therapy after surgery, cytokine therapy in 2 patients, systemic chemotherapy in a patient, and molecular-targeting therapy in 2 patients, respectively. The median overall survival was 15 months (range, 1-44 months). Overall, the 1- and 3-year survival rates were 67 and 33%, respectively. Most of the patients had symptomatic advanced disease at diagnosis. Even though nephrectomy was performed, systemic treatment was not effective in such patients.
authors.affiliation: The Department of Urology, Daisan Hospital of Jikei University School of Medicine.
authors.forename: Takehito
authors.initials: T
authors.lastname: Naruoka
authors.affiliation: The Department of Urology, Daisan Hospital of Jikei University School of Medicine.
authors.forename: Nozomu
authors.initials: N
authors.lastname: Furuta
authors.affiliation: The Department of Urology, Jikei University School of Medicine.
authors.forename: Takashi
authors.initials: T
authors.lastname: Hatano
authors.affiliation: The Department of Urology, Jikei University School of Medicine.
authors.forename: Jun
authors.initials: J
authors.lastname: Miki
authors.affiliation: The Department of Urology, Jikei University School of Medicine.
authors.forename: Masaya
authors.initials: M
authors.lastname: Murakami
authors.affiliation: The Department of Urology, Jikei University School of Medicine.
authors.forename: Shin
authors.initials: S
authors.lastname: Egawa
mesh_terms: D000328:Adult; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000628:therapy*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology / Q000628:therapy*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging