title: Analysis of pesticide and veterinary drug residues in baby food by liquid chromatography coupled to Orbitrap high resolution mass spectrometry.
abstract: Pesticide and veterinary drug residues have been simultaneously determined in several baby foods as meat, fish and vegetable-based baby food. A generic extraction method without clean-up step was applied. Moreover, the use of a representative matrix for proper quantification of all target compounds was studied and the best results were obtained when vegetable-based baby food was used as representative matrix, allowing the reliable quantification of more than 300 compounds. The method was validated and good recoveries were obtained for most of compounds at concentrations higher than 50 µg kg(-1). Limits of detection (LOD) ranged from 0.5 to 50 µg kg(-1), whereas limits of quantification (LOQ) were established between 10 and 100 µg kg(-1). Limits of identification (LOIs) ranged from 0.5 to 50 µg kg(-1). This method was applied to the analysis of 46 different baby food samples and no positive samples were found.
authors.affiliation: Research Group "Analytical Chemistry of Contaminants", Department of Chemistry and Physics, Research Centre for Agricultural and Food Biotechnology (BITAL), University of Almería, Agrifood Campus of International Excellence, ceiA3, E-04120 Almería, Spain.
authors.forename: María Luz
authors.initials: ML
authors.lastname: Gómez-Pérez
authors.affiliation: Research Group "Analytical Chemistry of Contaminants", Department of Chemistry and Physics, Research Centre for Agricultural and Food Biotechnology (BITAL), University of Almería, Agrifood Campus of International Excellence, ceiA3, E-04120 Almería, Spain.
authors.forename: Roberto
authors.initials: R
authors.lastname: Romero-González
authors.affiliation: Research Group "Analytical Chemistry of Contaminants", Department of Chemistry and Physics, Research Centre for Agricultural and Food Biotechnology (BITAL), University of Almería, Agrifood Campus of International Excellence, ceiA3, E-04120 Almería, Spain.
authors.forename: Vidal José
authors.initials: VJ
authors.lastname: Luis Martínez
authors.affiliation: Research Group "Analytical Chemistry of Contaminants", Department of Chemistry and Physics, Research Centre for Agricultural and Food Biotechnology (BITAL), University of Almería, Agrifood Campus of International Excellence, ceiA3, E-04120 Almería, Spain. Electronic address: agarrido@ual.es.
authors.forename: Antonia
authors.initials: A
authors.lastname: Garrido Frenich
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004350:Drug Residues / Q000032:analysis*; D005506:Food Contamination; D006801:Humans; D007223:Infant; D007225:Infant Food / Q000032:analysis*; D057230:Limit of Detection; D010575:Pesticides / Q000032:analysis*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D014675:Vegetables / Q000737:chemistry; D019155:Veterinary Drugs / Q000032:analysis*
chemical_list: D010575:Pesticides; D019155:Veterinary Drugs
keywords: Baby food; Exactive-Orbitrap; Matrix effect; Pesticide; Representative matrix; Veterinary drug