title: 18-Year-Old Woman with an Embryonal Rhabdomyosarcoma of the Uterus in Statu Nascendi.
abstract: Background:We report a case of an 18-year-old woman with an embryonal rhabdomyosarcoma in statu nascendi.Case:A fist-sized embryonal rhabdomyosarcoma of the uterus filling the vaginal vault was diagnosed in an adolescent with virgo intacta suffering from therapy resistant vaginal discharge, bleeding and bulging mass for six months. Further imaging revealed one suspicious pelvine lymph node. Excision of the tumour including the intracervical stalk was performed and followed by systemic multiagent chemotherapy. PET-CT scan presented a complete response after the third cycle. Histological complete response was shown by laparoscopic dissection of regional pelvic lymph nodes and curettage.Conclusion:Uterine Rhabdomyosarcoma should be considered as differential diagnosis of therapy resistant vaginal flour and bleeding in young women. Fertility-sparing therapy is possible in selected exceptional cases.
authors.affiliation: FK-Erlangen, Erlangen.
authors.forename: O
authors.initials: O
authors.lastname: Strahl
authors.affiliation: Institute of Pathology, Friedrich-Alexander-Universitaet, Erlangen ; Comprehensive Cancer Center Erlangen-Nürnberg.
authors.forename: A
authors.initials: A
authors.lastname: Hartmann
authors.affiliation: FK-Erlangen, Erlangen.
authors.forename: F C
authors.initials: FC
authors.lastname: Thiel
authors.affiliation: FK-Erlangen, Erlangen ; Comprehensive Cancer Center Erlangen-Nürnberg.
authors.forename: M W
authors.initials: MW
authors.lastname: Beckmann
authors.affiliation: FK-Erlangen, Erlangen.
authors.forename: M P
authors.initials: MP
authors.lastname: Lux
keywords: embryonal rhabdomyosarcoma; sarcoma botryoides; uterine sarcoma; uterine tumor