title: Digestion modeling in the small intestine: impact of dietary fiber.
abstract: In this work, the modeling of the digestion in the small intestine is developed by investigating specifically the effects of dietary fiber. As our previous model, this new version takes into account the three main phenomena of digestion: transit of the bolus, degradation of feedstuffs and absorption through the intestinal wall. However the two main physiochemical characteristics of dietary fiber, namely viscosity and water holding capacity, lead us to substantially modify our initial model by emphasizing the role of water and its intricated dynamics with dry matter in the bolus. Various numerical simulations given by this new model are qualitatively in agreement with the positive effect of insoluble dietary fiber on the velocity of bolus and on its degradation all along the small intestine. These simulations reproduce the negative effect of soluble dietary fiber on digestion as it has been experimentally observed. Although, this model is generic and contains a large number of parameters but, to the best of our knowledge, it is among the first qualitative dynamical models of fiber influence on intestinal digestion.
authors.affiliation: Laboratoire de Mathématiques et Physique Théorique (UMR CNRS 7350), Fédération Denis Poisson (FR CNRS 2964), Université de Tours Faculté des Sciences et Techniques, Parc de Grandmont, F-37200 Tours, France; INRA, UR83 Recherches Avicoles, F-37380 Nouzilly, France. Electronic address: masoomeh.taghipoor@rennes.inra.fr.
authors.forename: M
authors.initials: M
authors.lastname: Taghipoor
authors.affiliation: Laboratoire de Mathématiques et Physique Théorique (UMR CNRS 7350), Fédération Denis Poisson (FR CNRS 2964), Université de Tours Faculté des Sciences et Techniques, Parc de Grandmont, F-37200 Tours, France.
authors.forename: G
authors.initials: G
authors.lastname: Barles
authors.affiliation: Laboratoire de Mathématiques et Physique Théorique (UMR CNRS 7350), Fédération Denis Poisson (FR CNRS 2964), Université de Tours Faculté des Sciences et Techniques, Parc de Grandmont, F-37200 Tours, France.
authors.forename: C
authors.initials: C
authors.lastname: Georgelin
authors.affiliation: Laboratoire de Mathématiques et Physique Théorique (UMR CNRS 7350), Fédération Denis Poisson (FR CNRS 2964), Université de Tours Faculté des Sciences et Techniques, Parc de Grandmont, F-37200 Tours, France.
authors.forename: J R
authors.initials: JR
authors.lastname: Licois
authors.affiliation: INRA, UR83 Recherches Avicoles, F-37380 Nouzilly, France.
authors.forename: P
authors.initials: P
authors.lastname: Lescoat
mesh_terms: D000818:Animals; D004043:Dietary Fiber; D004063:Digestion / Q000502:physiology*; D007421:Intestine, Small / Q000502:physiology*; D008954:Models, Biological
keywords: Insoluble dietary fiber; Modeling of intestinal digestion; Soluble dietary fiber; Water holding capacity