title: Enantioselective one-pot synthesis of ring-fused tetrahydroquinolines via aerobic oxidation and 1,5-hydride transfer/cyclization sequences.
abstract: Enantioselective organocatalytic synthesis of tetrahydroquinolines has been achieved via an aerobic oxidation and a 1,5-hydride transfer/cyclization sequence. The feature of this research is a one-pot transformation of 3-arylprop-2-en-1-ol derivatives into tetrahydroquinolines using a Ru(VII)-catalyzed aerobic oxidation and highly efficient internal redox reactions. The synthetically useful ring-fused tetrahydroquinoline derivatives are obtained in moderate yields and high levels of enantioselectivity.
authors.affiliation: Department of Chemistry, Soonchunhyang University , Asan, Chungnam 336-745, Korea.
authors.forename: Chang Won
authors.initials: CW
authors.lastname: Suh
authors.forename: Dae Young
authors.initials: DY
authors.lastname: Kim