title: [Laboratory test features of newly diagnosed adult HIV-infected patients in Ouagadougou (Burkina Faso)].
abstract: In a sub-Saharan African population of adults beginning care for HIV infection, we sought to describe some laboratory features and their correlation with disease progression. We retrospectively reviewed pretreatment laboratory records of recently diagnosed adults (Elisa test) beginning care at the Internal Medicine department of Yalgado Ouédraogo University Hospital between June 2009 and August 2010. The values have been classified according to WHO standards. During the study period, 177 patients were newly diagnosed as HIV-positive. Among them, 144 (81.4%) had CD4 counts below 350 cells/μL. The mean hemoglobin level was 10.3 ± 2.1 g/dL for women (n = 94) and 11.2 ± 2.8 g/dL for men (n = 67, p = 0.028), and 113 (71.1%) had anemia, 12 of them severe (7.5%). Anemia and lymphopenia were significantly correlated with a low CD4 count (p = 0.001 and 0.003 respectively). Six patients (3.4%) also had type 2 diabetes. Total cholesterol was normal in all patients, and 8 (10.4%) had hypertriglyceridemia. Hematopoietic, glycemic and lipid disorders seem relatively common in untreated black patients with HIV infection. A low CD4 count appears to predict hematopoietic cell deficits.
authors.affiliation: Service de médecine interne, CHU Yalgado Ouédraogo, 03 BP 7022, 03 Ouagadougou, Burkina Faso.
authors.forename: Y
authors.initials: Y
authors.lastname: Sagna
authors.affiliation: Service de médecine interne, CHU Yalgado Ouédraogo, 03 BP 7022, 03 Ouagadougou, Burkina Faso, Service d'hématologie, CHU Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
authors.forename: J
authors.initials: J
authors.lastname: Koulidiaty
authors.affiliation: Service de médecine interne, CHU Yalgado Ouédraogo, 03 BP 7022, 03 Ouagadougou, Burkina Faso.
authors.forename: I
authors.initials: I
authors.lastname: Diallo
authors.affiliation: Service de médecine interne, CHU Yalgado Ouédraogo, 03 BP 7022, 03 Ouagadougou, Burkina Faso.
authors.forename: A F
authors.initials: AF
authors.lastname: Sanou
authors.affiliation: Service de médecine interne, CHU Yalgado Ouédraogo, 03 BP 7022, 03 Ouagadougou, Burkina Faso.
authors.forename: P A
authors.initials: PA
authors.lastname: Bagbila
authors.affiliation: Laboratoire d'analyses médicales, centre médical Saint-Camille, Ouagadougou, Burkina Faso, Centre de recherche biomoléculaire Pietro-Annigoni, Ouagadougou, Burkina Faso.
authors.forename: T
authors.initials: T
authors.lastname: Sagna
authors.affiliation: Service de biochimie, CHU Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
authors.forename: I
authors.initials: I
authors.lastname: Nébié
authors.affiliation: Service de médecine interne, CHU Yalgado Ouédraogo, 03 BP 7022, 03 Ouagadougou, Burkina Faso.
authors.forename: O
authors.initials: O
authors.lastname: Guira
authors.affiliation: Service de médecine interne, CHU Yalgado Ouédraogo, 03 BP 7022, 03 Ouagadougou, Burkina Faso.
authors.forename: H
authors.initials: H
authors.lastname: Tiéno
authors.affiliation: Service de médecine interne, CHU Yalgado Ouédraogo, 03 BP 7022, 03 Ouagadougou, Burkina Faso.
authors.forename: Y J
authors.initials: YJ
authors.lastname: Drabo
mesh_terms: D000328:Adult; D000740:Anemia / Q000097:blood / Q000175:diagnosis; D002050:Burkina Faso; D018791:CD4 Lymphocyte Count; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000175:diagnosis; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D015658:HIV Infections / Q000097:blood*; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D012189:Retrospective Studies
chemical_list: D008055:Lipids
keywords: Burkina Faso; HIV; Sub-Saharan Africa; anemia; lipid defects; lymphopenia; neutropenia