title: [Familial spam (streptococcal pharyngitis associated myocarditis): is it a new entity or a coincidence?].
abstract: BACKGROUND
  Myocarditis is an inflammation of the myocardium. It is potentially life-threatening, with a wide range of clinical presentations and most often it is caused by various viral, bacterial or fungal infections.
  
  
  METHODS
  A 27 year-old man, previously hospitalized due to streptococcal tonsillitis, was admitted to ED because of chest pain. He presented with pain, tightness irradiating to both shoulders and arms and associated sweating and vomiting. The ECG revealed ST elevations on Leads: V5-V6, V7-V9, II, III, AVF and ST depressions on Leads V1-V3. Laboratory results showed elevated Liver enzymes, and positive troponin-5.766 ng/mL The patient showed clinical improvement with NSAIDs and was diagnosed with myocarditis. His brother was admitted to the hospital a year earlier with a sore throat accompanied by chest pain and was diagnosed with perimyocarditis.
  
  
  CONCLUSIONS
  The family history of myocarditis after a streptococcal infection, affecting two brothers a year apart from each other, raises the possibility that there is a genetic component responsible for an individuaLs susceptibility to develop myocarditis.
authors.forename: Gil
authors.initials: G
authors.lastname: Merav
authors.forename: Aura
authors.initials: A
authors.lastname: Yassin
authors.forename: Inna
authors.initials: I
authors.lastname: Rosenfeld
authors.forename: Amer
authors.initials: A
authors.lastname: Hussein
mesh_terms: D000208:Acute Disease; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D002637:Chest Pain / Q000175:diagnosis* / Q000209:etiology; D003937:Diagnosis, Differential; D004198:Disease Susceptibility; D004562:Electrocardiography / Q000379:methods; D005192:Family Health; D006801:Humans; D008297:Male; D009205:Myocarditis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D035781:Siblings; D013290:Streptococcal Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D014069:Tonsillitis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal