title: Phytochemical Investigations on Chemical Constituents of Achillea tenuifolia Lam.
abstract: Achillea tenuifolia Lam. (Asteraceae) afforded a methanolic extract from which after fractionation in solvents with different polarities, two known flavones 3', 5- dihydroxy- 4', 6, 7- trimethoxy flavone (eupatorine, compound 3), 5- hydroxy- 3',4', 6, 7- tetramethoxyflavone (compound 4), besides stearic acid (compound 1), lupeol (compound 2), daucosterol (β- sitosterol 3-O- β- D- glucopyranoside, compound 5), 2, 4- dihydroxy methyl benzoate (compound 6) were isolated for the first time. The structure of isolated compounds was elucidated by means of different spectroscopic methods such as UV, IR, Mass and 1H- NMR (1D and 2D) and 13C-NMR. For further confirming the structures of isolated compounds, comparison of the spectral data of them with those reported in the litratures have been done.
authors.affiliation: Department of Pharmacognosy and Biotechnology, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran.
authors.forename: Shirin
authors.initials: S
authors.lastname: Moradkhani
authors.affiliation: Department of Medicinal Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran. ; Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Farzad
authors.initials: F
authors.lastname: Kobarfard
authors.affiliation: Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. ; Department of Pharmacognosy and Biotechnolgy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Seyed Abdol Majid
authors.initials: SA
authors.lastname: Ayatollahi
keywords: Achillea tenuifolia; Asteraceae; Daucosterol; Eupatorine; Lupeol