title: Validation of the Brain Symptom and Impact Questionnaire (BASIQ) to assess symptom and quality of life in brain metastases.
abstract: OBJECTIVE
  To validate the Brain Symptom and Impact Questionnaire (BASIQ) version 1.0 for brain metastases.
  
  
  METHODS
  Patients with brain metastases and their healthcare professionals (HCPs) assessed the relevance of the BASIQ on a 0-10 scale with 10 as extremely relevant.
  
  
  RESULTS
  A total of 52 patients and 20 HCPs participated in this study. In total, 95% of HCPs and 85% of patients found all items relevant. Balance and walking ability were rated relevant by 100% of patients and HCPs. Headache, nausea, energy, memory and ability to do housework were also rated relevant by 100% of HCPs. Over 95% of patients determined the items of ability to do housework, tiredness, energy, vision, memory and putting ideas into words as relevant. There were no items rated below 7 by patients or below 5 by HCPs.
  
  
  CONCLUSIONS
  This study indicates that BASIQ version 1.0 has valid content items encompassing disease-related symptom and impact on daily living.
authors.affiliation: Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Gillian
authors.initials: G
authors.lastname: Bedard
authors.forename: Saurabh
authors.initials: S
authors.lastname: Ray
authors.forename: Liying
authors.initials: L
authors.lastname: Zhang
authors.forename: Liang
authors.initials: L
authors.lastname: Zeng
authors.forename: David
authors.initials: D
authors.lastname: Cella
authors.forename: Erin
authors.initials: E
authors.lastname: Wong
authors.forename: Cyril
authors.initials: C
authors.lastname: Danjoux
authors.forename: May
authors.initials: M
authors.lastname: Tsao
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Barnes
authors.forename: Arjun
authors.initials: A
authors.lastname: Sahgal
authors.forename: Lori
authors.initials: L
authors.lastname: Holden
authors.forename: Natalie
authors.initials: N
authors.lastname: Lauzon
authors.forename: Edward
authors.initials: E
authors.lastname: Chow
mesh_terms: D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000523:psychology* / Q000556:secondary*; D005260:Female; D006282:Health Personnel / Q000523:psychology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires; D055815:Young Adult
keywords: BASIQ; brain metastases; content validation; quality of life; questionnaire