title: Clinical aspects of work-related asthma: past achievements, persistent challenges, and emerging triggers.
abstract: OBJECTIVE
  The aim of this article was to address common clinical questions pertaining to work-related asthma (WRA).
  
  
  METHODS
  This review is based on a presentation on WRA at the American College of Chest Physicians Course on Clinical Aspects of Occupational and Environmental Lung Disease, held in Toronto in 2013, and supplemented by a PubMed search of publications to 2013.
  
  
  RESULTS
  Seven clinical questions are addressed in relation to definitions, causes, diagnosis, management and emerging triggers, and challenges of WRA.
  
  
  CONCLUSIONS
  Although knowledge is expanding in this area, there remain challenges and uncertainties, particularly in the prevention of WRA.
authors.affiliation: From the Toronto Western Hospital and University of Toronto, Ontario, Canada.
authors.forename: Susan
authors.initials: S
authors.lastname: Tarlo
mesh_terms: D000395:Air Pollutants, Occupational / Q000009:adverse effects; D059366:Asthma, Occupational / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D015984:Causality; D004185:Disability Evaluation; D006801:Humans; D007509:Irritants; D016273:Occupational Exposure / Q000009:adverse effects; D012307:Risk Factors; D014051:Toluene 2,4-Diisocyanate / Q000009:adverse effects; D014942:Workers' Compensation
chemical_list: D000395:Air Pollutants, Occupational; D007509:Irritants; D014051:Toluene 2,4-Diisocyanate