title: Therapy of a clear cell adenocarcinoma of unknown primary arising in the abdominal wall after cesarean section and after hysterectomy.
abstract: Clear cell carcinoma arising in a cesarean section scar is extremely rare. Due to the rarity of the tumor, treatment strategies still need to be further elucidated. We report a case of a woman with a clear cell carcinoma of 10 cm outside the abdominal cavity in her cesarean section scar. Staging surgery revealed two lymph nodes with metastatic dissemination of a clear cell adenocarcinoma. After staging surgery, six cycles of adjuvant chemotherapy with carboplatin/paclitaxel were performed. The patient was disease-free 10 months after completion of chemotherapy. Comprehensive treatment consisting of radical surgery combined with adjuvant chemotherapy can be considered for this uncommon tumor entity.
authors.affiliation: Gynecologic Cancer Unit, Comprehensive Cancer Center, Department of Gynecology and Gynecologic Oncology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria, stefanie.aust@meduniwien.ac.at.
authors.forename: Stefanie
authors.initials: S
authors.lastname: Aust
authors.forename: Denise
authors.initials: D
authors.lastname: Tiringer
authors.forename: Christoph
authors.initials: C
authors.lastname: Grimm
authors.forename: Josefine
authors.initials: J
authors.lastname: Stani
authors.forename: Martin
authors.initials: M
authors.lastname: Langer
mesh_terms: D000008:Abdominal Neoplasms / Q000209:etiology / Q000556:secondary* / Q000628:therapy*; D034861:Abdominal Wall / Q000473:pathology / Q000601:surgery; D018262:Adenocarcinoma, Clear Cell / Q000209:etiology / Q000556:secondary* / Q000628:therapy*; D002585:Cesarean Section / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects; D008875:Middle Aged; D009382:Neoplasms, Unknown Primary; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D016896:Treatment Outcome