title: [Effect of type 2 diabetes with hypertension on cognitive function-a study on elderly living in the communities of Beijing].
abstract: OBJECTIVE
  To study the effects of type 2 diabetes (T2DM) with hypertension on cognitive function in those community-based elderly who were aged 60 and over, in Beijing.
  
  
  METHODS
  82 patients with T2DM, 142 patients with both T2DM and hypertension and 277 normal controls were investigated in this study. Both methods as: the Montreal Cognitive Assessment (MoCA) and Mini-Mental Status Examination (MMSE)were used to determine cognitive change.
  
  
  RESULTS
  The total MMSE scores showed significant decrease between T2DM with hypertension and controls [(28.42 ± 1.52) vs. (28.88 ± 1.47), P < 0.05]. The MoCA score of the total scores [(25.20 ± 3.91) vs. (26.50 ± 3.29), P < 0.05], sub-scores of visuospatial, executive [(3.60 ± 1.56) vs. (3.96 ± 1.18), P < 0.05] and language [(2.10 ± 0.80) vs. (2.37 ± 0.80), P < 0.05] significantly decreased in T2DM patients with hypertension and in the normal controls. Data from the Multiple logistic regression analysis showed that older age and less education were risk factors for cognitive impairment.
  
  
  CONCLUSIONS
  T2DM and hypertension damaged the cognitive function of patients.
authors.affiliation: Key Laboratory of Geriatrics. Email: gaoxinbj@hotmail.com.
authors.forename: Xin
authors.initials: X
authors.lastname: Gao
authors.affiliation: Editorial Department of Chinese Journal of Geriatrics.
authors.forename: Chunbo
authors.initials: C
authors.lastname: Duan
authors.affiliation: Key Laboratory of Geriatrics.
authors.forename: Li
authors.initials: L
authors.lastname: Bao
authors.affiliation: Department of Neurology, Beijing Hospital and Beijing Institute of Geriatrics, Ministry of Health, Beijing 100730, China.
authors.forename: Huiyan
authors.initials: H
authors.lastname: Yu
authors.affiliation: Department of Neurology, Beijing Hospital and Beijing Institute of Geriatrics, Ministry of Health, Beijing 100730, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Qin
authors.affiliation: Key Laboratory of Geriatrics.
authors.forename: Ruomei
authors.initials: R
authors.lastname: Qi
authors.affiliation: Key Laboratory of Geriatrics.
authors.forename: Fangkun
authors.initials: F
authors.lastname: Gao
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D003071:Cognition; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D008297:Male; D008875:Middle Aged