title: Unilateral peripapillary intrachoroidal cavitation and optic disk rotation.
abstract: OBJECTIVE
  To examine the morphology of the optic nerve head in patients with unilateral peripapillary intrachoroidal cavitations (PICCs).
  
  
  METHODS
  The hospital-based observational study included patients with unilateral PICCs. Tomographic images of the parapapillary fundus were taken by enhanced depth imaging mode of optical coherent tomography. The ocular biometric parameters were compared between the affected eyes and the contralateral unaffected eyes.
  
  
  RESULTS
  The study population consisted of 30 patients with a mean age of 42.7 ± 13.8 years (range: 22-72 years), mean axial length of 26.7 ± 2.4 mm (range: 22.00-32.30 mm), and mean refractive error of -8.71 ± 5.21 diopters (range: -20.50 to +0.50 diopters). In the eyes affected by PICC as compared with the contralateral eyes, the vertical (P = 0.001) and the minimal optic disk diameters (P = 0.01) were significantly shorter, the ratio of minimal to maximal disk diameter was significantly lower (P = 0.03), and the angle of disk rotation was significantly higher (P < 0.001).
  
  
  CONCLUSIONS
  In patients with unilateral PICCS, the eyes with PICCs had optic disks that were more spindlelike configured because of a disk rotation around the vertical axis and around the sagittal axis as compared with the contralateral eyes.
authors.affiliation: *Department of Ophthalmology and Vision Science, Eye & ENT Hospital, Shanghai Medical College, Fudan University, Shanghai, China; †Key Laboratory of Myopia of State Health Ministry, and Key Laboratory of Visual Impairment and Restoration of Shanghai, Shanghai, China; ‡Department of Ophthalmology, Medical Faculty Mannheim, Ruprecht-Karls-University, Heidelberg, Germany; and §State Key Laboratory of Medical Neurobiology, Institutes of Brain Science, Fudan University, Shanghai, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Dai
authors.forename: Jost B
authors.initials: JB
authors.lastname: Jonas
authors.forename: Zhihong
authors.initials: Z
authors.lastname: Ling
authors.forename: Xiaoying
authors.initials: X
authors.lastname: Wang
authors.forename: Xinghuai
authors.initials: X
authors.lastname: Sun
mesh_terms: D000328:Adult; D000368:Aged; D001699:Biometry; D015862:Choroid Diseases / Q000175:diagnosis*; D005260:Female; D006068:Gonioscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D012399:Rotation; D041623:Tomography, Optical Coherence; D014065:Tonometry, Ocular; D055815:Young Adult