title: Complement activation.
abstract: When activated, the system of serum proteins known as complement is involved in a wide variety of responses to inflammatory and noxious stimuli. In this article Eric Brown and Michael Frank review the activation of complement by the classical and alternative pathways and discuss some of its biological effects.
authors.affiliation: Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20205 U.S.A.
authors.forename: E J
authors.initials: EJ
authors.lastname: Brown
authors.forename: M M
authors.initials: MM
authors.lastname: Frank