title: Neutrophil-to-Lymphocyte Ratio Positively Correlates to Age in Healthy Population.
abstract: BACKGROUND
  Neutrophil to lymphocyte ratio (NLR) was reported to be an independent easy-to-measure marker for many diseases, while the distribution of NLR in healthy population was not formally studied. So we investigated NLR in healthy people in this study.
  
  
  METHODS
  Data include NLR, systolic pressure, diastolic pressure, and body mass index (BMI), which were collected from 3,262 healthy population. Correlations of NLR with variables were analyzed with SPSS16.0.
  
  
  RESULTS
  Results demonstrated that NLR was positively associated with age (P < 0.001). The eldest age group possessed the highest NLR and the youngest age group had the lowest NLR. NLR was also slightly positively associated with systolic pressure, diastolic pressure, and BMI (P < 0.001).
  
  
  CONCLUSIONS
  Older people possessed relatively high NLR in healthy population.
authors.affiliation: Department of Clinical Laboratory, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guanzhou, Guangdong Province, People's Republic of China.
authors.forename: Jian
authors.initials: J
authors.lastname: Li
authors.affiliation: Health Examination Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guanzhou, Guangdong Province, People's Republic of China.
authors.forename: Qingyu
authors.initials: Q
authors.lastname: Chen
authors.affiliation: Department of Clinical Laboratory, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guanzhou, Guangdong Province, People's Republic of China.
authors.forename: Xiaohong
authors.initials: X
authors.lastname: Luo
authors.affiliation: Department of Prevention and Health Care, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guanzhou, Guangdong Province, People's Republic of China.
authors.forename: Jun
authors.initials: J
authors.lastname: Hong
authors.affiliation: Department of Clinical Laboratory, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guanzhou, Guangdong Province, People's Republic of China.
authors.forename: Kunyi
authors.initials: K
authors.lastname: Pan
authors.affiliation: Department of Clinical Laboratory, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guanzhou, Guangdong Province, People's Republic of China.
authors.forename: Xianghua
authors.initials: X
authors.lastname: Lin
authors.affiliation: Department of Clinical Laboratory, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guanzhou, Guangdong Province, People's Republic of China.
authors.forename: Xiaoqiang
authors.initials: X
authors.lastname: Liu
authors.affiliation: Department of Clinical Laboratory, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guanzhou, Guangdong Province, People's Republic of China.
authors.forename: Lijun
authors.initials: L
authors.lastname: Zhou
authors.affiliation: Department of Clinical Laboratory, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guanzhou, Guangdong Province, People's Republic of China.
authors.forename: Han
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Clinical Laboratory, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guanzhou, Guangdong Province, People's Republic of China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Xu
authors.affiliation: Department of Clinical Laboratory, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guanzhou, Guangdong Province, People's Republic of China.
authors.forename: Hongyu
authors.initials: H
authors.lastname: Li
authors.affiliation: Department of Clinical Laboratory, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guanzhou, Guangdong Province, People's Republic of China.
authors.forename: Chaohui
authors.initials: C
authors.lastname: Duan
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D015415:Biomarkers / Q000032:analysis*; D001794:Blood Pressure; D015992:Body Mass Index; D016022:Case-Control Studies; D004194:Disease / Q000145:classification*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008214:Lymphocytes / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000473:pathology*; D011379:Prognosis; D055815:Young Adult
chemical_list: D015415:Biomarkers
keywords: NLR; clinical parameter; immunity; lymphocyte; neutrophil