title: Urinary iodine as an iodine deficiency test in lung transplant recipients in order to prevent iodine deficiency disorders.
abstract: BACKGROUND
  In Poland, lung transplantation (LTx) as a routine method began in 2004, and since then, the Silesian Center for Heart Disease in Zabrze 85 LTx has performed (54 single-lung transplantations, 30 double-lung transplantations, and 1 heart-lung) transplantation. The recommendation to take vitamin supplements (without specific indication of the iodine content) does not apply to another iodine prophylaxis in patients after lung transplantation, excluding patients with known thyroid disease. The aim of this study was to assess thyroid gland function based on hormones and urinary iodine (UI) concentration in patients after LTx.
  
  
  METHODS
  UI analysis was performed in 19 lung recipients (12 men and 7 women; mean age: 46.2 ± 12.47 years, BMI: 21 ± 2.25) and compared to TSH, free T3, and free T4.
  
  
  RESULTS
  Sufficient UI was observed only in 2 (9%) samples. In 12 samples (54.5%), mild iodine deficiency was recorded, in 4 samples (18.2%) moderate iodine deficiency was noted, and in 3 (13.6%) severe iodine deficiency was found. No correlation between BMI and UI, as well as hormones concentration, was observed. No correlation was revealed when analyzed samples were divided by patient sex.
  
  
  CONCLUSIONS
  Although thyroid gland hormones were in the normal range, we found moderate, mild, and severe iodine deficiency in the majority of analyzed samples. Measurements of urinary iodine in lung transplant recipients should accompany thyroid hormone measurements as an iodine deficiency test and in order to prevent iodine deficiency disorders.
authors.affiliation: Department of Radioisotope Diagnostic and Radiopharmaceuticals, Medical University of Silesia in Katowice, Sosnowiec, Poland.
authors.forename: Anita
authors.initials: A
authors.lastname: Stanjek-Cichoracka
authors.affiliation: Laboratory of Transplant Immunology, Silesian Center for Heart Diseases, Zabrze, Poland.
authors.forename: Sławomir
authors.initials: S
authors.lastname: Żegleń
authors.affiliation: Laboratory of Transplant Immunology, Silesian Centre for Heart Diseases, Zabrze, Poland.
authors.forename: Elżbieta
authors.initials: E
authors.lastname: Woźniak-Grygiel
authors.affiliation: Laboratory of Transplant Immunology, Silesian Centre for Heart Diseases, Zabrze, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Laszewska
authors.affiliation: Laboratory of Transplant Immunology, Silesian Centre for Heart Diseases, Zabrze, Poland.
authors.forename: Piotr
authors.initials: P
authors.lastname: Sindera
authors.affiliation: Department and Clinic of Cardiac Surgery and Transplantology, Silesian Centre for Heart Diseases, Zabrze, Poland.
authors.forename: Jacek
authors.initials: J
authors.lastname: Wojarski
authors.affiliation: Department and Clinic of Cardiac Surgery and Transplantology, Silesian Centre for Heart Diseases, Zabrze, Poland.
authors.forename: Marek
authors.initials: M
authors.lastname: Ochman
authors.affiliation: Department and Clinic of Cardiac Surgery and Transplantology, Silesian Centre for Heart Diseases, Zabrze, Poland.
authors.forename: Wojtek
authors.initials: W
authors.lastname: Karolak
authors.affiliation: Department and Clinic of Cardiac Surgery and Transplantology, Silesian Centre for Heart Diseases, Zabrze, Poland.
authors.forename: Marian
authors.initials: M
authors.lastname: Zembala
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007455:Iodine / Q000172:deficiency* / Q000652:urine*; D016040:Lung Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011044:Poland; D013963:Thyroid Hormones / Q000097:blood; D066027:Transplant Recipients
chemical_list: D013963:Thyroid Hormones; D007455:Iodine