title: [Spinal anesthesia with low doses of local anesthetic in patients with multiple trauma].
abstract: The aim of the study was to compare the safety of low doses of local anesthetic spinal anesthesia with the traditional by frequency of hypotension and bradycardia in patients with polytrauma. We observed 144 patients with multiple injuries, including fractures of the lower limbs: I group patients 7.5-10 mg intrathecal bupivacaine group II--15-20 mg of bupivacaine. The relative risk (RR) of hypotension for the control group compared with the study was 9.3 (95 % CI 2.79-39.3). The relative risk (RR) of insufficient duration of anesthesia when using unilateral technique was not significantly higher--2.56 (95% CI 0.73-11.32). Found that spinal anesthesia with low doses of local anesthetic can significantly reduce the risk of hypotension and bradycardia in patients with multiple injuries, but during prolonged surgical interventions unilateral spinal anesthesia is advisable to combine with catheterization of the epidural space.
authors.forename: Iu L
authors.initials: IuL
authors.lastname: Kuchyn
mesh_terms: D000328:Adult; D000775:Anesthesia, Spinal / Q000379:methods*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D001919:Bradycardia / Q000517:prevention & control; D002045:Bupivacaine / Q000008:administration & dosage*; D002406:Catheterization, Peripheral; D004334:Drug Administration Schedule; D004824:Epidural Space; D005260:Female; D006801:Humans; D007022:Hypotension / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D009104:Multiple Trauma / Q000601:surgery*; D012306:Risk
chemical_list: D000779:Anesthetics, Local; D002045:Bupivacaine