title: Surgical strategies in the therapy of non-small cell lung cancer.
abstract: Lung cancer represents the leading cause of cancer mortality worldwide. Despite improvements in preoperative staging, surgical techniques, neoadjuvant/adjuvant options and postoperative care, there are still major difficulties in significantly improving survival, especially in locally advanced non-small cell lung cancer (NSCLC). To date, surgical resection is the primary mode of treatment for stage I and II NSCLC and has become an important component of the multimodality therapy of even more advanced disease with a curative intention. In fact, in NSCLC patients with solitary distant metastases, surgical interventions have been discussed in the last years. Accordingly, this review displays the recent surgical strategies implemented in the therapy of NSCLC patients.
authors.affiliation: Feras Al-Shahrabani, Daniel Vallböhmer, Sebastian Angenendt, Wolfram T Knoefel, Department of Surgery A, Section of Thoracic Surgery, Heinrich Heine University and University Hospital, 40225 Düsseldorf, NRW, Germany.
authors.forename: Feras
authors.initials: F
authors.lastname: Al-Shahrabani
authors.affiliation: Feras Al-Shahrabani, Daniel Vallböhmer, Sebastian Angenendt, Wolfram T Knoefel, Department of Surgery A, Section of Thoracic Surgery, Heinrich Heine University and University Hospital, 40225 Düsseldorf, NRW, Germany.
authors.forename: Daniel
authors.initials: D
authors.lastname: Vallböhmer
authors.affiliation: Feras Al-Shahrabani, Daniel Vallböhmer, Sebastian Angenendt, Wolfram T Knoefel, Department of Surgery A, Section of Thoracic Surgery, Heinrich Heine University and University Hospital, 40225 Düsseldorf, NRW, Germany.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Angenendt
authors.affiliation: Feras Al-Shahrabani, Daniel Vallböhmer, Sebastian Angenendt, Wolfram T Knoefel, Department of Surgery A, Section of Thoracic Surgery, Heinrich Heine University and University Hospital, 40225 Düsseldorf, NRW, Germany.
authors.forename: Wolfram T
authors.initials: WT
authors.lastname: Knoefel
keywords: Multimodality therapy; Neoadjuvant/adjuvant therapy; Non-small cell lung cancer; Solitary distant metastases; Surgical techniques