title: Consensus of clinical neurorestorative progress in patients with complete chronic spinal cord injury.
abstract: Currently, there is a lack of effective therapeutic methods to restore neurological function for chronic complete spinal cord injury (SCI) by conventional treatment. Neurorestorative strategies with positive preclinical results have been translated to the clinic, and some patients have gotten benefits and their quality of life has improved. These strategies include cell therapy, neurostimulation or neuromodulation, neuroprosthesis, neurotization or nerve bridging, and neurorehabilitation. The aim of this consensus by 31 experts from 20 countries is to show the objective evidence of clinical neurorestoration for chronic complete SCI by the mentioned neurorestorative strategies. Complete chronic SCI patients are no longer told, "nothing can be done." The clinical translation of more effective preclinical neurorestorative strategies should be encouraged as fast as possible in order to benefit patients with incurable CNS diseases. This manuscript is published as part of the International Association of Neurorestoratology (IANR) special issue of Cell Transplantation.
authors.affiliation: Center of Neurorestoratology, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
authors.forename: Hongyun
authors.initials: H
authors.lastname: Huang
authors.forename: Tiansheng
authors.initials: T
authors.lastname: Sun
authors.forename: Lin
authors.initials: L
authors.lastname: Chen
authors.forename: Gustavo
authors.initials: G
authors.lastname: Moviglia
authors.forename: Elena
authors.initials: E
authors.lastname: Chernykh
authors.forename: Klaus
authors.initials: K
authors.lastname: von Wild
authors.forename: Haluk
authors.initials: H
authors.lastname: Deda
authors.forename: Kyung-Sun
authors.initials: KS
authors.lastname: Kang
authors.forename: Anand
authors.initials: A
authors.lastname: Kumar
authors.forename: Sang Ryong
authors.initials: SR
authors.lastname: Jeon
authors.forename: Shaocheng
authors.initials: S
authors.lastname: Zhang
authors.forename: Giorgio
authors.initials: G
authors.lastname: Brunelli
authors.forename: Albert
authors.initials: A
authors.lastname: Bohbot
authors.forename: Maria Dolors
authors.initials: MD
authors.lastname: Soler
authors.forename: Jianjun
authors.initials: J
authors.lastname: Li
authors.forename: Alexandre Fogaça
authors.initials: AF
authors.lastname: Cristante
authors.forename: Haitao
authors.initials: H
authors.lastname: Xi
authors.forename: Gelu
authors.initials: G
authors.lastname: Onose
authors.forename: Helmut
authors.initials: H
authors.lastname: Kern
authors.forename: Ugo
authors.initials: U
authors.lastname: Carraro
authors.forename: Hooshang
authors.initials: H
authors.lastname: Saberi
authors.forename: Hari Shanker
authors.initials: HS
authors.lastname: Sharma
authors.forename: Alok
authors.initials: A
authors.lastname: Sharma
authors.forename: Xijing
authors.initials: X
authors.lastname: He
authors.forename: Dafin
authors.initials: D
authors.lastname: Muresanu
authors.forename: Shiqing
authors.initials: S
authors.lastname: Feng
authors.forename: Ali
authors.initials: A
authors.lastname: Otom
authors.forename: Dajue
authors.initials: D
authors.lastname: Wang
authors.forename: Koichi
authors.initials: K
authors.lastname: Iwatsu
authors.forename: Jike
authors.initials: J
authors.lastname: Lu
authors.forename: Adeeb
authors.initials: A
authors.lastname: Al-Zoubi
mesh_terms: D002908:Chronic Disease; D006801:Humans; D009416:Nerve Regeneration; D044968:Regenerative Medicine / Q000941:ethics; D013119:Spinal Cord Injuries / Q000628:therapy*; D033581:Stem Cell Transplantation / Q000009:adverse effects; D057170:Translational Research, Biomedical / Q000941:ethics