title: Phototandem catalysis: efficient synthesis of 3-ester-3-hydroxy-2-oxindoles by a visible light-induced cyclization of diazoamides through an aerobic oxidation sequence.
abstract: An unprecedented phototandem catalysis based on a single iridium photocatalyst has been successfully developed. This powerful strategy consists of two mechanistically distinct catalytic cycles, namely, photocatalytic energy transfer (ET) and single electron transfer (SET). The novel protocol allows a rapid and efficient construction of biologically and synthetically important 3-ester-3-hydroxy-2-oxindole derivatives from readily available diazoamides through a cyclization/aerobic oxidation sequence under very mild conditions.
authors.affiliation: Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei 430079 (China), Fax: (+86) 27-6786-2041 http://chem-xiao.ccnu.edu.cn.
authors.forename: Xu-Dong
authors.initials: XD
authors.lastname: Xia
authors.forename: Yan-Liang
authors.initials: YL
authors.lastname: Ren
authors.forename: Jia-Rong
authors.initials: JR
authors.lastname: Chen
authors.forename: Xing-Long
authors.initials: XL
authors.lastname: Yu
authors.forename: Liang-Qiu
authors.initials: LQ
authors.lastname: Lu
authors.forename: You-Quan
authors.initials: YQ
authors.lastname: Zou
authors.forename: Jian
authors.initials: J
authors.lastname: Wan
authors.forename: Wen-Jing
authors.initials: WJ
authors.lastname: Xiao
mesh_terms: D000577:Amides / Q000737:chemistry*; D061565:Cycloaddition Reaction; D004579:Electron Transport; D004735:Energy Transfer; D007211:Indoles / Q000138:chemical synthesis / Q000737:chemistry*; D007495:Iridium / Q000737:chemistry; D008027:Light; D010084:Oxidation-Reduction; D000078183:Oxindoles
chemical_list: D000577:Amides; D007211:Indoles; D000078183:Oxindoles; C022960:2-oxindole; D007495:Iridium
keywords: cycloaddition; diazoamides; iridium; photocatalysis; visible light