title: [Every sixth patient in amiodarone treatment develops thyrotoxicosis or hypothyreosis].
abstract: Amiodarone is associated with multiple side effects among which a substantial number of patients are suffering from amiodarone-induced thyroid disease. In this review we present difficulties in diagnosing, sub typing and treating amiodarone-induced thyroid disease and give views on the future of this drug and one of the alternatives, dronedarone. Amiodarone holds a place in modern medicine due to its unique antiarrhythmic effects and associated thyroid diseases requires collaboration between cardiologists and endocrinologists due to the complexity hereof.
authors.affiliation: Medicinsk Afdeling, Regionshospitalet -Viborg, Heibergs Allé 4, 8800 Viborg. jimmi.olsen@viborg.rm.dk.
authors.forename: Jimmi Sloth
authors.initials: JS
authors.lastname: Olsen
authors.forename: Allan
authors.initials: A
authors.lastname: Carlé
authors.forename: Henrik Holm
authors.initials: HH
authors.lastname: Thomsen
mesh_terms: D000638:Amiodarone / Q000009:adverse effects* / Q000031:analogs & derivatives; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D000077764:Dronedarone; D011307:Drug Prescriptions / Q000706:statistics & numerical data; D006801:Humans; D007037:Hypothyroidism / Q000139:chemically induced* / Q000188:drug therapy / Q000453:epidemiology; D012307:Risk Factors; D013971:Thyrotoxicosis / Q000139:chemically induced* / Q000188:drug therapy / Q000453:epidemiology
chemical_list: D000889:Anti-Arrhythmia Agents; D000077764:Dronedarone; D000638:Amiodarone