title: Comparison of minimally invasive and open gastric transposition in children.
abstract: BACKGROUND
  Gastric transposition is an established method of esophageal replacement in children, and the use of minimally invasive techniques avoids the trauma of open access. The objective of this study was to compare outcomes of minimally invasive versus open gastric transposition in children.
  
  
  METHODS
  All cases of attempted laparoscopic-assisted gastric transposition at Great Ormond Street Hospital (GOSH), London, United Kingdom, between 2003 and 2012 were retrospectively reviewed. A comprehensive literature search was completed on MEDLINE for minimally invasive gastric transposition in children, and postoperative outcomes were collated. The outcomes from the retrospective review (single-center, GOSH) and the literature search (multicenter) were compared with those of the largest study on open gastric transposition consisting of 192 cases performed at GOSH.
  
  
  RESULTS
  In this retrospective review of 19 patients (mean age, 3.5 years; range, 0.4-15 years), the indications were long-gap esophageal atresia, postoperative, caustic, and idiopathic esophageal stricture, and esophageal dysmotility. Three cases were converted to laparotomy and excluded from subsequent analysis. There were one anastomotic leak, two strictures, and no deaths in this series. The literature search yielded a further 50 cases for comparison. Single-center (n=16) and multicenter (n=66) comparison of minimally invasive versus open technique (n=192) showed no difference in leak (6.3% and 16.7%, respectively, versus 12.0%; P=.701 and P=.398), stricture (12.5% and 15.2% versus 20.8%; P=.535 and P=.370), and mortality rates (0% and 1.5% versus 4.7%; P=1.000 and P=.461).
  
  
  CONCLUSIONS
  Minimally invasive gastric transposition is a safe and acceptable alternative to open surgery in children.
authors.affiliation: 1 Specialist Neonatal and Paediatric Surgery Department, Great Ormond Street Hospital for Children , London, United Kingdom .
authors.forename: Jessica
authors.initials: J
authors.lastname: Ng
authors.forename: Stavros P
authors.initials: SP
authors.lastname: Loukogeorgakis
authors.forename: Agostino
authors.initials: A
authors.lastname: Pierro
authors.forename: Edward M
authors.initials: EM
authors.lastname: Kiely
authors.forename: Paolo
authors.initials: P
authors.lastname: De Coppi
authors.forename: Kate
authors.initials: K
authors.lastname: Cross
authors.forename: Joe
authors.initials: J
authors.lastname: Curry
mesh_terms: D000293:Adolescent; D057868:Anastomotic Leak; D002057:Burns, Chemical / Q000150:complications; D002648:Child; D002675:Child, Preschool; D004933:Esophageal Atresia / Q000601:surgery; D015154:Esophageal Motility Disorders / Q000601:surgery*; D004940:Esophageal Stenosis / Q000209:etiology / Q000601:surgery*; D005260:Female; D006801:Humans; D007223:Infant; D010535:Laparoscopy / Q000379:methods; D008297:Male; D012189:Retrospective Studies; D013270:Stomach / Q000637:transplantation*; D006113:United Kingdom