title: [Acute mesenteric ischemia: do biomarkers contribute to diagnosis?].
abstract: Acute mesenteric ischemia is an emergency condition that requires immediate therapy. Despite advances in the fields of surgery and intensive therapy, the mortality of this condition remains high. This is due to the broad variability of clinical presentations and non-specific laboratory findings, which delay the diagnosis allowing the ischemia to progress and further worsening the patients' chances of survival. Thus, there is a significant need for reliable and enhanced serological markers of intestinal ischemia. The authors review the traditionally used and novel experimental serological markers for early diagnosis of mesenteric ischemia.
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar I. Sebészeti Klinika Budapest Üllői út 78. 1082.
authors.forename: Olivér
authors.initials: O
authors.lastname: Rosero
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar I. Sebészeti Klinika Budapest Üllői út 78. 1082.
authors.forename: László
authors.initials: L
authors.lastname: Harsányi
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar I. Sebészeti Klinika Budapest Üllői út 78. 1082.
authors.forename: Attila
authors.initials: A
authors.lastname: Szijártó
mesh_terms: D000208:Acute Disease; D015415:Biomarkers / Q000097:blood* / Q000378:metabolism; D002956:Citrulline / Q000097:blood; D062465:Claudin-3 / Q000097:blood; D042241:Early Diagnosis; D004630:Emergencies; D050556:Fatty Acid-Binding Proteins / Q000097:blood; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism; D005982:Glutathione Transferase / Q000097:blood; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007527:Isoenzymes / Q000097:blood; D019344:Lactic Acid / Q000097:blood; D007958:Leukocyte Count; D065666:Mesenteric Ischemia / Q000097:blood / Q000175:diagnosis*; D011237:Predictive Value of Tests; D012709:Serum Albumin / Q000378:metabolism; D000075462:Serum Albumin, Human
chemical_list: D015415:Biomarkers; D062465:Claudin-3; D050556:Fatty Acid-Binding Proteins; D005338:Fibrin Fibrinogen Degradation Products; D007527:Isoenzymes; D012709:Serum Albumin; C036309:fibrin fragment D; C561522:ischemia-modified albumin; D002956:Citrulline; D019344:Lactic Acid; D005982:Glutathione Transferase; C119995:glutathione S-transferase alpha; D000075462:Serum Albumin, Human
keywords: diagnosis; diagnosztika; mesenterialis ischaemia; mesenteric ischemia; serological marker; szerológiai marker