title: The past 10 years of gastroenterology and hepatology-reflections and predictions.
abstract: In November 2004, the very first issue of this journal featured articles on the pathogenesis of ulcerative colitis, mechanisms leading to chronic pancreatitis, and treatment of recurrent Clostridium-difficile-associated diarrhoea. Although those topics might seem familiar, much has changed in the intervening years in our understanding, diagnosis and treatment of many different diseases across the field of gastroenterology and hepatology. Nonetheless, many challenges remain. Here, we have asked five of our Advisory Board members-international experts across different subspecialties in gastroenterology and hepatology-to reflect on the progress and frustrations of the past 10 years. They also comment on where effort and money should be invested now, as well as their predictions for progress in the next 10 years.
authors.affiliation: Division of Liver Disease, Box 1123, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, Room 11-70C, New York, NY 10029-6574, USA.
authors.forename: Scott L
authors.initials: SL
authors.lastname: Friedman
authors.affiliation: Division of Gastroenterology and Hepatology, Houston Methodist Hospital, 6550 Fannin Street, SM 1001, Houston, TX 77030, USA.
authors.forename: Eamonn M M
authors.initials: EM
authors.lastname: Quigley
authors.affiliation: Hotchkiss Brain Institute and Snyder Institute for Chronic Diseases, Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, AB T2N 4N1, Canada.
authors.forename: Keith A
authors.initials: KA
authors.lastname: Sharkey
authors.affiliation: University Administration Building, The Chinese University of Hong Kong, 1/F, Room 101, Shatin, NT, Hong Kong SAR, The People's Republic of China.
authors.forename: Joseph J Y
authors.initials: JJ
authors.lastname: Sung
authors.affiliation: Department of Medicine, Cell Biology &Molecular Physiology and Human Genetics, University of Pittsburgh and UPMC, Room 401.4, 3708 Fifth Avenue, Pittsburgh, PA 15231, USA.
authors.forename: David C
authors.initials: DC
authors.lastname: Whitcomb
mesh_terms: D005544:Forecasting; D005762:Gastroenterology / Q000266:history* / Q000639:trends; D005767:Gastrointestinal Diseases / Q000628:therapy; D049674:History, 21st Century; D006801:Humans; D008107:Liver Diseases / Q000628:therapy