title: Bodily fluid analysis of non-serum samples using point-of-care testing with iSTAT and Piccolo analyzers versus a fixed hospital chemistry analytical platform.
abstract: BACKGROUND
  Forward deployed military medical units can provide sophisticated medical care with limited resources. Point-of-Care Testing (POCT) may facilitate care and expedite diagnosis. This study assessed the accuracy of results for POCT for non-serum samples (pleural, peritoneal, and cerebrospinal fluid) using iSTAT and Piccolo hand-held devices compared with results obtained using a hospital chemistry analyzer.
  
  
  METHODS
  Pleural, peritoneal, and cerebrospinal fluids obtained during routine care were simultaneously analyzed on a Vitros 5600 automated clinical chemistry hospital analyzer, iSTAT, and Piccolo POCT devices.
  
  
  RESULTS
  POCT results were highly correlated with the Vitros 5600 for pleural fluid LDH, glucose, and triglycerides (TG); for peritoneal fluid bilirubin, TG, glucose, albumin, and protein; and glucose for cerebrospinal fluid.
  
  
  CONCLUSIONS
  POCT results for non-serum samples from pleural, peritoneal, and cerebrospinal fluid correlate with standard hospital chemistry analysis. The results of this study demonstrate potential for possible new diagnostic roles for POCT in resource-limited environments.
authors.affiliation: Department of Medicine, Tripler Army Medical Center, Honolulu, HI (WL).
authors.forename: William
authors.initials: W
authors.lastname: Londeree
authors.affiliation: Department of Medicine, Tripler Army Medical Center, Honolulu, HI (WL).
authors.forename: Konrad
authors.initials: K
authors.lastname: Davis
authors.affiliation: Department of Medicine, Tripler Army Medical Center, Honolulu, HI (WL).
authors.forename: Donald
authors.initials: D
authors.lastname: Helman
authors.affiliation: Department of Medicine, Tripler Army Medical Center, Honolulu, HI (WL).
authors.forename: Jude
authors.initials: J
authors.lastname: Abadie
mesh_terms: D001826:Body Fluids / Q000737:chemistry*; D002555:Cerebrospinal Fluid / Q000737:chemistry; D019963:Clinical Chemistry Tests / Q000295:instrumentation* / Q000592:standards*; D006801:Humans; D010537:Peritoneum; D010994:Pleura; D000067716:Point-of-Care Testing / Q000592:standards*