title: Novel aspects of encapsulation and delivery using polymersomes.
abstract: Polymersomes are nanoscopic (e.g. nanometer-sized) vesicles formed by amphiphilic block copolymers. They represent the more robust and versatile macromolecular counterparts to the well-established lipid vesicles or liposomes. Recently, considerable efforts have been made to produce them in a uniform and functional manner. New techniques such as artificial endocytosis and electroporation have also been developed to achieve payload encapsulation. In this mini-review, we discuss these and other recent developments in making polymersomes an actual alternative for biomedical applications.
authors.affiliation: Department of Chemistry and The MRC/UCL Centre for Medical Molecular Virology, University College London, 20 Gordon Street, London WC1H 0AJ, UK.
authors.forename: Léa
authors.initials: L
authors.lastname: Messager
authors.affiliation: Department of Chemistry and The MRC/UCL Centre for Medical Molecular Virology, University College London, 20 Gordon Street, London WC1H 0AJ, UK.
authors.forename: Jens
authors.initials: J
authors.lastname: Gaitzsch
authors.affiliation: Department of Chemistry and The MRC/UCL Centre for Medical Molecular Virology, University College London, 20 Gordon Street, London WC1H 0AJ, UK.
authors.forename: Luca
authors.initials: L
authors.lastname: Chierico
authors.affiliation: Department of Chemistry and The MRC/UCL Centre for Medical Molecular Virology, University College London, 20 Gordon Street, London WC1H 0AJ, UK. Electronic address: g.battaglia@ucl.ac.uk.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Battaglia
mesh_terms: D004339:Drug Compounding / Q000379:methods*; D016503:Drug Delivery Systems; D011108:Polymers / Q000737:chemistry*
chemical_list: D011108:Polymers