title: 'Imperfect' conjugated polymer nanoparticles from MEH-PPV for bioimaging and Fe(III) sensing.
abstract: A simple and effective method was reported for the preparation from MEH-PPV of conjugated polymer nanoparticles (Pdots) that are water-soluble and well dispersed. The as-prepared Pdots show bright orange fluorescence at a quantum yield up to 32.37%. The fluorescence intensity of Pdots can be quenched with good selectively by the successive addition of Fe(3+) . In addition, the as-obtained Pdots were applied to the imaging of HeLa cells, and exhibited low cytotoxicity and excellent biocompatibility.
authors.affiliation: College of Chemistry and Life Science, Zhejiang Normal University, Jinhua, 321004, China.
authors.forename: Jingyi
authors.initials: J
authors.lastname: Xu
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhou
authors.forename: Guifang
authors.initials: G
authors.lastname: Cheng
authors.forename: Shuxian
authors.initials: S
authors.lastname: Liu
authors.forename: Meiting
authors.initials: M
authors.lastname: Dong
authors.forename: Chaobiao
authors.initials: C
authors.lastname: Huang
mesh_terms: D005453:Fluorescence; D006367:HeLa Cells / Q000187:drug effects; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007501:Iron / Q000032:analysis*; D008670:Metals / Q000737:chemistry; D018613:Microscopy, Confocal; D057054:Molecular Imaging / Q000379:methods; D053758:Nanoparticles / Q000737:chemistry*; D009994:Osmolar Concentration; D011108:Polymers / Q000737:chemistry*; D045663:Quantum Dots / Q000737:chemistry* / Q000633:toxicity; D012995:Solubility; D012997:Solvents / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D014753:Vinyl Compounds / Q000737:chemistry*
chemical_list: D008670:Metals; D011108:Polymers; D012997:Solvents; D014753:Vinyl Compounds; C520682:poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene); D007501:Iron
keywords: Fe(III) ion; Pdots; bioimaging; selective