title: Effect of an educational program in primary care: the case of lipid control in cardio-cerebrovascular prevention.
abstract: Lowering blood cholesterol levels reduces the risk of coronary heart disease. However, the effect of interventions depends on the patients' adherence to treatment. Primary care plays an important role in the detection, treatment and monitoring of disease, therefore different educational programs (EP) have been implemented to improve disease management in general practice. The present study is aimed to assess whether a general practitioner auditing and feedback EP may improve dyslipidaemia management in a primary care setting and to evaluate patients' adherence to prescribed lipid-lowering treatment. The quality of cardiovascular and cerebrovascular disease prevention before and after the implementation of an EP offered to 25 general practitioners (GPs), was evaluated. Clinical and prescription data on patients receiving at least one lipid-lowering treatment was collected. To evaluate the quality of the healthcare service provided, clinical and biochemical outcomes, and drug-utilization, process indicators were set up. Adherence was evaluated before and after the EP as the "Medication Possession Ratio" (MPR). A correlation analysis was carried out to estimate the effect of the MPR in achieving pre-defined clinical end-points. Prescription data for lipid-lowering drugs was collected in a sample of 839 patients. While no differences in the achievement of blood lipid targets were observed, a slight but significant improvement of the MPR was registered after the EP (MPR >0.8=64.2% vs 60.6%, p=0.0426). Moreover, high levels of statin adherence were associated with the achievement of total blood cholesterol target (OR=3.3 for MPR >0.8 vs MPR <0.5, 95% CI:1.7-6.7) or LDL therapeutic goal (OR=3.3 for MPR >0.8 vs MPR <0.5, 95% CI:1.5-7.2). The EP partially improved the defined clinical targets; probably, a more patient-based approach could be more appropriate to achieve the defined target. Further studies are needed to identify how healthcare services can be improved.
authors.affiliation: Department of Clinical and Experimental Medicine and Pharmacology, Pharmacology Unit, University of Messina, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Arcoraci
authors.affiliation: Pfizer, Department of Outcome Research Roma, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Santoni
authors.affiliation: Department of Clinical and Experimental Medicine and Pharmacology, Pharmacology Unit, University of Messina, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Ferrara
authors.affiliation: Italian National Research Center on Aging (I.N.R.C.A.), Scientific Direction Ancona, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Furneri
authors.affiliation: Department of Clinical and Experimental Medicine and Pharmacology, Pharmacology Unit, University of Messina, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Cannata
authors.affiliation: Department of Clinical and Experimental Medicine and Pharmacology, Pharmacology Unit, University of Messina, Italy.
authors.forename: J
authors.initials: J
authors.lastname: Sultana
authors.affiliation: "Caserta-1" Local Health Unit, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Moretti
authors.affiliation: "Caserta-1" Local Health Unit, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Di Luccio
authors.affiliation: "Caserta-1" Local Health Unit, Italy.
authors.forename: D U
authors.initials: DU
authors.lastname: Tari
authors.affiliation: "Caserta-1" Local Health Unit, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Pagliaro
authors.affiliation: Di.Bi.MIS, University of Palermo, Internal Medicine Division ARNAS Civico, Palermo, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Corrao
authors.affiliation: "Caserta-1" Local Health Unit, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Tari
mesh_terms: D000368:Aged; D002318:Cardiovascular Diseases / Q000517:prevention & control*; D002561:Cerebrovascular Disorders / Q000517:prevention & control*; D050171:Dyslipidemias / Q000188:drug therapy*; D005260:Female; D058005:General Practitioners / Q000193:education*; D006801:Humans; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D011320:Primary Health Care