title: Ameloblastic fibrosarcoma of the mandible: A case report and mini review.
abstract: Ameloblastic fibrosarcoma (AFS) is a rare malignant odontogenic neoplasm of the jaw. AFS is characteristically composed of a benign odontogenic epithelium and a malignant mesenchymal component. The posterior region of the mandible is the predominantly occupied site. In the present report, a new case of AFS in a 22-year-old male that originated from ameloblastic fibroma was described. Histologically, the tumor showed biphasic components: Benign epithelium and a malignant mesenchymal component. Immunochemical findings revealed that the tumor cells were positive for cluster of differentiation (CD) 34, vimentin, Ki-67 and p53, but negative for smooth muscle actin, S-100, CD68 and desmin. The clinical presentation, radiographic appearances and treatment measures were additionally described and reviewed.
authors.affiliation: Department of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China.
authors.forename: Yuan-Yuan
authors.initials: YY
authors.lastname: Hu
authors.affiliation: Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, Hubei 430079, P.R. China.
authors.forename: Mo-Hong
authors.initials: MH
authors.lastname: Deng
authors.affiliation: Department of Pathology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China.
authors.forename: Ling-Ling
authors.initials: LL
authors.lastname: Yuan
authors.affiliation: Department of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China.
authors.forename: Yu-Ming
authors.initials: YM
authors.lastname: Niu
keywords: ameloblastic fibroma; ameloblastic fibrosarcoma; case report