title: A ratiometric fluorescent probe for sensing HOCl based on a coumarin-rhodamine dyad.
abstract: We developed a ratiometric fluorescent probe for sensing HOCl based on coumarin and rhodamine acid that is directly used as a detection moiety. The probe shows high selectivity and sensitivity toward HOCl under best working conditions of myeloperoxidase by which HOCl can be generated from hydrogen peroxide and chloride.
authors.affiliation: Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P. R. China. bxzhao@sdu.edu.cn.
authors.forename: Yan-Ru
authors.initials: YR
authors.lastname: Zhang
authors.forename: Xin-Peng
authors.initials: XP
authors.lastname: Chen
authors.lastname: Jing-Shao
authors.forename: Jia-Yi
authors.initials: JY
authors.lastname: Zhang
authors.forename: Qiong
authors.initials: Q
authors.lastname: Yuan
authors.forename: Jun-Ying
authors.initials: JY
authors.lastname: Miao
authors.forename: Bao-Xiang
authors.initials: BX
authors.lastname: Zhao
mesh_terms: D000818:Animals; D002460:Cell Line; D003374:Coumarins / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006997:Hypochlorous Acid / Q000032:analysis*; D051379:Mice; D015394:Molecular Structure; D012235:Rhodamines / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
chemical_list: D003374:Coumarins; D005456:Fluorescent Dyes; D012235:Rhodamines; D006997:Hypochlorous Acid; C030123:coumarin