title: Application of Intravascular Ultrasound in the Emergency Diagnosis and Treatment of Patients with ST-Segment Elevation Myocardial Infarction.
abstract: OBJECTIVE
  This study aimed to examine the application of intravascular ultrasound (IVUS) in ST-segment elevation myocardial infarction (STEMI) patients with high thrombus burden (thrombus grade ≥3) undergoing emergency diagnosis and primary percutaneous coronary intervention.
  
  
  METHODS
  Eighty STEMI patients were enrolled and randomly assigned to the IVUS-guided group (38 patients) or non-IVUS group (42 patients). Stent implantation was performed in non-IVUS group patients. IVUS group patients were further divided into low-risk and high-risk patients on the basis of IVUS evaluation for determining whether stenting should be performed. Major adverse cardiac event (MACE) rates, changes in the left ventricular end-diastolic diameter (LVEDD) and ejection fraction (EF) values, and stent numbers were examined during hospitalization, and follow-up was performed at 1, 3, 6, and 12 months postoperatively.
  
  
  RESULTS
  During hospitalization, there were no significant differences in the MACE rates, LVEDD, and EF values and in the follow-up outcomes at 1, 3, 6, and 12 months postoperatively among the patients in the 2 groups (P > 0.05). A significantly lower number of stents were implanted in the IVUS group than in the non-IVUS group patients (P < 0.05).
  
  
  CONCLUSIONS
  During the IVUS-guided emergency intervention, enhanced antithrombotic therapy and best medical care for low-risk STEMI patients may be feasible.
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Henan Science and Technology University, Luoyang, China.
authors.forename: Hong-Xia
authors.initials: HX
authors.lastname: Wang
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Henan Science and Technology University, Luoyang, China.
authors.forename: Ping-Shuan
authors.initials: PS
authors.lastname: Dong
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Henan Science and Technology University, Luoyang, China.
authors.forename: Zhi-Juan
authors.initials: ZJ
authors.lastname: Li
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Henan Science and Technology University, Luoyang, China.
authors.forename: Hong-Lei
authors.initials: HL
authors.lastname: Wang
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Henan Science and Technology University, Luoyang, China.
authors.forename: Ke
authors.initials: K
authors.lastname: Wang
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Henan Science and Technology University, Luoyang, China.
authors.forename: Xiang-Yong
authors.initials: XY
authors.lastname: Liu
mesh_terms: D004632:Emergency Medical Services / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000628:therapy*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional / Q000379:methods*
keywords: IVUS; STEMI; aspiration thrombectomy; stent