title: Molecular mechanisms in tumor-cell killing by activated macrophages.
abstract: Macrophages kill tumor cells with and without the aid of antibody and evidence suggests that secreted cytotoxic substances are at work in each system. Here Dolph Adams and Carl Nathan discuss the likely involvement in both pathways of several such substances including cytolytic protease and hydrogen peroxide.
authors.affiliation: Departments of Pathology and Microbiology and Immunology, Duke University, Durham, NC 27710, USA.
authors.forename: D O
authors.initials: DO
authors.lastname: Adams
authors.affiliation: Department of Cellular Physiology and Immunology, The Rockefeller University, New York, NY 10021, USA.
authors.forename: C F
authors.initials: CF
authors.lastname: Nathan