title: Multitasking in Gonadotropin-Releasing Hormone Neuron Dendrites.
abstract: Gonadotropin-releasing hormone (GnRH) neurons integrate synaptic information in their dendrites in order to precisely control GnRH secretion and hence fertility. Recent discoveries concerning the structure and function of GnRH neuron dendrites have shed new light on the control of GnRH neuron excitability and GnRH secretion. This work suggests that GnRH neurons have a unique projection to the median eminence that possesses both dendritic and axonal properties. We propose that this 'dendron' projection allows GnRH neurons to multitask and integrate information in ways that would not be possible in a classically envisioned axon projection.
authors.affiliation: Centre for Neuroendocrinology, Department of Physiology, University of Otago School of Medical Sciences, Dunedin, New Zealand.
authors.forename: Karl J
authors.initials: KJ
authors.lastname: Iremonger
authors.forename: Allan E
authors.initials: AE
authors.lastname: Herbison
mesh_terms: D000818:Animals; D003712:Dendrites / Q000502:physiology*; D007987:Gonadotropin-Releasing Hormone / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D008473:Median Eminence / Q000166:cytology; D009434:Neural Pathways / Q000166:cytology / Q000502:physiology; D009474:Neurons / Q000166:cytology / Q000502:physiology*
chemical_list: D007987:Gonadotropin-Releasing Hormone