title: Electrochemical sensor for chloramphenicol based on novel multiwalled carbon nanotubes@molecularly imprinted polymer.
abstract: Herein, we present a novel electrochemical sensor for the determination of chloramphenicol (CAP), which is based on multiwalled carbon nanotubes@molecularly imprinted polymer (MWCNTs@MIP), mesoporous carbon (CKM-3) and three-dimensional porous graphene (P-r-GO). Firstly, 3-hexadecyl-1-vinylimidazolium chloride (C16VimCl) was synthetized by using 1-vinylimidazole and 1-chlorohexadecane as precursors. Then, C16VImCl was used to improve the dispersion of MWCNT and as monomer to prepare MIP on MWCNT surface to obtain MWCNTs@MIP. After that, the obtained MWCNTs@MIP was coated on the CKM-3 and P-r-GO modified glassy carbon electrode to construct an electrochemical sensor for the determination of CAP. The parameters concerning this assay strategy were carefully considered. Under the optimal conditions, the electrochemical sensor offered an excellent response for CAP. The linear response ranges were 5.0 × 10(-9)-5 × 10(-7)mol L(-1) and 5.0 × 10(-7)-4.0 × 10(-6), respectively, and the detection limit was 1.0 × 10(-10)mol L(-1). The electrochemical sensor was applied to determine CAP in real samples with satisfactory results.
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, PR China; Department of Resources and Environment, Baoshan University, Baoshan 678000, PR China.
authors.forename: Guangming
authors.initials: G
authors.lastname: Yang
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, PR China. Electronic address: fqzhao@whu.edu.cn.
authors.forename: Faqiong
authors.initials: F
authors.lastname: Zhao
mesh_terms: D015374:Biosensing Techniques; D002701:Chloramphenicol / Q000302:isolation & purification*; D006108:Graphite / Q000737:chemistry; D057230:Limit of Detection; D054802:Molecular Imprinting; D037742:Nanotubes, Carbon / Q000737:chemistry; D011108:Polymers / Q000737:chemistry
chemical_list: D037742:Nanotubes, Carbon; D011108:Polymers; D002701:Chloramphenicol; D006108:Graphite
keywords: Chloramphenicol; Mesoporous carbon; Molecularly imprinted polymer; Multiwalled carbon nanotubes; Porous graphene