title: Isotretinoin-induced arthritis mimicking both rheumatoid arthritis and axial spondyloarthritis.
abstract: Isotretinoin is used for the treatment of various acne lesions that are resistant to other treatments. The most frequent rheumatologic side effect of isotretinoin is transient muscle and/or joint pains. Here, we report a case with bilateral wrist and metacarpophalangeal joint arthritis and unilateral sacroiliitis associated with isotretinoin usage to attract attention, particularly from physiatrists, rheumatologists and dermatologists, to this rare adverse effect of isotretinoin.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Ankara Numune Training and Research Hospital, Ankara, Turkey.
authors.forename: Ozlem
authors.initials: O
authors.lastname: Yilmaz Tasdelen
authors.affiliation: Department of Physical Medicine and Rehabilitation, Ankara Numune Training and Research Hospital, Ankara, Turkey.
authors.forename: Fatma Gul
authors.initials: FG
authors.lastname: Yurdakul
authors.affiliation: Department of Radiology, Ankara Numune Training and Research Hospital, Ankara, Turkey.
authors.forename: Semra
authors.initials: S
authors.lastname: Duran
authors.affiliation: Department of Physical Medicine and Rehabilitation, Ankara Numune Training and Research Hospital, Ankara, Turkey.
authors.forename: Hatice
authors.initials: H
authors.lastname: Bodur
mesh_terms: D000152:Acne Vulgaris / Q000175:diagnosis / Q000188:drug therapy*; D001172:Arthritis, Rheumatoid / Q000139:chemically induced* / Q000175:diagnosis; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D015474:Isotretinoin / Q000009:adverse effects* / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D010147:Pain Measurement; D016059:Range of Motion, Articular / Q000502:physiology; D018570:Risk Assessment; D058566:Sacroiliitis / Q000139:chemically induced* / Q000175:diagnosis; D012720:Severity of Illness Index; D025241:Spondylarthritis / Q000139:chemically induced* / Q000175:diagnosis; D055815:Young Adult
chemical_list: D015474:Isotretinoin
keywords: acne; arthritis; isotretinoin; retinoid; sacroiliitis