title: High-speed circuit training vs hypertrophy training to improve physical function in sarcopenic obese adults: a randomized controlled trial.
abstract: BACKGROUND
  Progressive loss of muscle and strength with age is often coincident with increases in adiposity, leading to a condition called sarcopenic obesity. Studies have shown sarcopenic obese adults to be at higher risk for declines in physical function. Despite this rising public health concern, no intervention studies currently exist in this population.
  
  
  METHODS
  A total of 21 sarcopenic obese adults, 60 years or older, were randomized into two groups, strength/hypertrophy (SH, n=9) and high-speed circuit (HSC, n=8) and were trained for 15 weeks. The primary outcome was the SPPB modified as a measure of physical function, assessed by assessors blinded to randomization. Secondary outcomes were lower body and upper body power and strength, instrumental activities of daily living (IADL), ratings of perceived exertion (RPE), body fat % (BF%), skeletal muscle index (SMI), and grip strength (GRP).
  
  
  RESULTS
  For the SPPB results favored HSC over SH (1.1, 95% CI (-.1 to 2.4), p=.08) and showed a moderate effect size (Hedge g=0.6, 95% CI (-0.4, 1.6)). For secondary outcomes, lower body power (mean difference=158 W, 95% CI (2, 315); p=.01) and RPE (mean difference=-1.5, 95% CI (-2.9, -0.12); p=.04) also favored HSC. IADL, SMI, BF%, upper and lower body strength and upper body power, showed no statistically significant differences between groups.
  
  
  CONCLUSIONS
  Considering the moderate effect size, the large treatment effect shown by the upper limit of the 95% CI, the low perceived exertion, and no adverse effects, HSC training should be further investigated with a larger sample size in sarcopenic obese adults.
authors.affiliation: University of Miami, Laboratory of Neuromuscular Research and Active Aging, Department of Kinesiology and Sports Sciences, Coral Gables, FL, United States.
authors.forename: Anoop
authors.initials: A
authors.lastname: Balachandran
authors.affiliation: University of Miami, Laboratory of Neuromuscular Research and Active Aging, Department of Kinesiology and Sports Sciences, Coral Gables, FL, United States.
authors.forename: Steven N
authors.initials: SN
authors.lastname: Krawczyk
authors.affiliation: University of Miami, Laboratory of Neuromuscular Research and Active Aging, Department of Kinesiology and Sports Sciences, Coral Gables, FL, United States.
authors.forename: Melanie
authors.initials: M
authors.lastname: Potiaumpai
authors.affiliation: University of Miami, Laboratory of Neuromuscular Research and Active Aging, Department of Kinesiology and Sports Sciences, Coral Gables, FL, United States; Miller School of Medicine, Center on Aging, University of Miami, Miami, FL, United States. Electronic address: jsignorile@miami.edu.
authors.forename: Joseph F
authors.initials: JF
authors.lastname: Signorile
mesh_terms: D000203:Activities of Daily Living; D050154:Adiposity; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000473:pathology / Q000502:physiology; D065327:Circuit-Based Exercise; D005260:Female; D006801:Humans; D006984:Hypertrophy; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength; D018482:Muscle, Skeletal / Q000473:pathology / Q000503:physiopathology; D009765:Obesity / Q000150:complications* / Q000503:physiopathology / Q000628:therapy*; D055070:Resistance Training; D055948:Sarcopenia / Q000150:complications* / Q000503:physiopathology / Q000628:therapy*; D016037:Single-Blind Method
keywords: Elderly; Power training; Resistance training