title: Autoimmune diseases: defects in immune specificity rather than a loss of suppressor cells.
abstract: An argument that autoimmune responses arise not because immunoregulation is faulty but because somatic mutation in lymphocytes generates clones with autoreactive potential.
authors.affiliation: MRC Autoimmunity Research Unit, University of Otago Medical School, PO Box 913, Dunedin, New Zealand.
authors.forename: J G
authors.initials: JG
authors.lastname: Knight