title: [Genomics in medicine].
abstract: The development of new fields of study in genetics, as the -omic sciences (transcriptomics, proteomics, metabolomics), has allowed the study of the regulation and expression of genomes. Therefore, nowadays it is possible to study global alterations--in the whole genome--and their effect at the protein and metabolic levels. Importantly, this new way of studying genetics has opened new areas of knowledge, and new cellular mechanisms that regulate the functioning of biological systems have been elucidated. In the clinical field, in the last years new molecular tools have been implemented. These tools are favorable to a better classification, diagnosis and prognosis of several human diseases. Additionally, in some cases best treatments, which improve the quality of life of patients, have been established. Due to the previous assertion, it is important to review and divulge changes in the study of genetics as a result of the development of the -omic sciences, which is the aim of this review.
authors.affiliation: Unidad de Investigación Médica en Genética Humana, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Distrito Federal, México. fasalam@prodigy.net.mx.
authors.forename: Ruth
authors.initials: R
authors.lastname: Ruiz Esparza-Garrido
authors.forename: Miguel Angel
authors.initials: MA
authors.lastname: Velázquez-Flores
authors.forename: Diego Julio
authors.initials: DJ
authors.lastname: Arenas-Aranda
authors.forename: Fabio
authors.initials: F
authors.lastname: Salamanca-Gómez
mesh_terms: D023281:Genomics; D006801:Humans; D008511:Medicine / Q000379:methods*
keywords: Expression; Genes; Genetics; Genomics; Human diseases; Regulation