title: [Autoinflammatory bone disorders in childhood].
abstract: Chronic non-bacterial osteomyelitis (CNO) is an autoinflammatory disease with unpredictable, painful courses of osteolytic lesions in the bones. CNO is frequently associated with psoriasis and inflammatory bowel disease. In cases with multifocal lesions the term chronic recurrent multifocal osteomyelitis (CRMO) is preferably used. SAPHO (synovitis, acne, pustulosis palmoplantaris, hyperostosis and osteitis) syndrome is regarded as CRMO in adults. New knowledge of the hereditary forms like Majeed syndrome, deficiency of IL-1-receptor antagonist and cherubism is described.
authors.affiliation: Børneafdelingen, Aarhus Universitetshospital, Brendstrupgaardsvej 100, 8200 Aarhus N. E-mail: agneziob@rm.dk.
authors.forename: Agnes
authors.initials: A
authors.lastname: Ziobrowska Bech
authors.forename: Troels
authors.initials: T
authors.lastname: Herlin
mesh_terms: D020083:Acquired Hyperostosis Syndrome / Q000503:physiopathology; D000742:Anemia, Dyserythropoietic, Congenital / Q000503:physiopathology; D002636:Cherubism / Q000503:physiopathology; D002648:Child; D056660:Hereditary Autoinflammatory Diseases / Q000503:physiopathology; D006801:Humans; D007153:Immunologic Deficiency Syndromes; D010009:Osteochondrodysplasias / Q000503:physiopathology*; D010019:Osteomyelitis / Q000503:physiopathology; D017472:Receptors, Interleukin-1 / Q000037:antagonists & inhibitors
chemical_list: D017472:Receptors, Interleukin-1