title: Development of a modified hand mobility in scleroderma (HAMIS) test and its potential as an outcome measure in systemic sclerosis.
abstract: OBJECTIVE
  To modify the hand mobility in scleroderma (HAMIS) test by reducing the number of items and amount of equipment needed, and to evaluate the construct validity of this modified HAMIS (mHAMIS).
  
  
  METHODS
  Our retrospective study is based on 266 patients previously examined using the original HAMIS test. Data were divided into 3 groups depending on disease duration after onset: (1) 0-3 years, (2) 3.1-5 years, and (3) 5.1-9 years. Disease variables included were skin involvement using the disease subset and the modified Rodnan skin score (mRSS), and digital lesions. Cronbach's alpha coefficient was calculated separately for limited (lcSSc) and diffuse systemic sclerosis (dcSSc) for the right and left hand, and for the groups with different disease duration. The construct validity of the mHAMIS was assessed by searching for a correlation with hand skin score.
  
  
  RESULTS
  An mHAMIS test consisting of finger flexion, finger extension, finger abduction, and dorsal extension was developed. The internal consistency of this test was 0.78, 0.83, and 0.73 in the 3 groups with different disease duration. In the whole study group, mHAMIS showed a significant correlation with mRSS and hand skin score (rs=0.39 and 0.43, respectively), and was able to discriminate between lcSSc and dcSSc (p=0.001), and between patients with and without ulcers (p=0.015).
  
  
  CONCLUSIONS
  The mHAMIS involves 4 easily measurable items and has the potential to be a relevant clinical measure of outcome in the evaluation of fibrotic skin involvement in SSc.
authors.affiliation: From the Section of Rheumatology, Department of Clinical Sciences, Lund University, Lund, Sweden.G. Sandqvist, Reg OT, PhD; J-Å. Nilsson, BSc; D.M. Wuttge, MD, PhD; R. Hesselstrand, MD, PhD, G, Section of Rheumatology, Department of Clinical Sciences, Lund University. gunnel.sandqvist@med.lu.se.
authors.forename: Gunnel
authors.initials: G
authors.lastname: Sandqvist
authors.affiliation: From the Section of Rheumatology, Department of Clinical Sciences, Lund University, Lund, Sweden.G. Sandqvist, Reg OT, PhD; J-Å. Nilsson, BSc; D.M. Wuttge, MD, PhD; R. Hesselstrand, MD, PhD, G, Section of Rheumatology, Department of Clinical Sciences, Lund University.
authors.forename: Jan-Åke
authors.initials: JÅ
authors.lastname: Nilsson
authors.affiliation: From the Section of Rheumatology, Department of Clinical Sciences, Lund University, Lund, Sweden.G. Sandqvist, Reg OT, PhD; J-Å. Nilsson, BSc; D.M. Wuttge, MD, PhD; R. Hesselstrand, MD, PhD, G, Section of Rheumatology, Department of Clinical Sciences, Lund University.
authors.forename: Dirk M
authors.initials: DM
authors.lastname: Wuttge
authors.affiliation: From the Section of Rheumatology, Department of Clinical Sciences, Lund University, Lund, Sweden.G. Sandqvist, Reg OT, PhD; J-Å. Nilsson, BSc; D.M. Wuttge, MD, PhD; R. Hesselstrand, MD, PhD, G, Section of Rheumatology, Department of Clinical Sciences, Lund University.
authors.forename: Roger
authors.initials: R
authors.lastname: Hesselstrand
mesh_terms: D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D004185:Disability Evaluation; D005260:Female; D005384:Finger Joint / Q000503:physiopathology; D050823:Hand Joints / Q000503:physiopathology*; D018737:Hand Strength / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D016059:Range of Motion, Articular / Q000502:physiology*; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012595:Scleroderma, Systemic / Q000175:diagnosis*; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index
keywords: HAND MOBILITY IN SCLERODERMA; MODIFIED HAND MOBILITY IN SCLERODERMA; SYSTEMIC SCLEROSIS