title: Relationship of Lipid Profile and Serum Ferritin levels with Acute Myocardial Infarction.
abstract: BACKGROUND
  National Health and Nutrition Examination Survey (NHANES III), 1988-1994, first time reported a significant, positive association in iron storage and heart disease risk. Thereafter several researchers have found an association between iron overload, serum ferritin (SF) and MI. No such Indian study was available in the literature and so we decided to find out the relation of lipid profile and Serum Ferritin with myocardial infarction (MI).
  
  
  METHODS
  Fifty indian patients of AMI (study group) and fifty indian healthy volunteers (control group) were included for the present study. Lipid profile including TC, HDL-c, LDL-c, VLDL-c & TG and SF levels were estimated in all subjects.
  
  
  RESULTS
  Mean ± SD of TC level was 250.64 ± 25.61, of HDL-c was 36.52 ± 2.86, of LDL-c was 165.69 ± 26.80, of VLDL-c was 42.35 ± 8.53 and of TG was 211.83 ± 42.65 in study group while these values were 174.46±47.68, 43.2±12.52, 98.37±41.13, 32.88±21.45 and 164.42±107.29 respectively in control group. All the parameters were found not only raised in patients of acute myocardial infarction (AMI) but were also statistically significant when compared with control group (p=<0.01). Mean ± SD of SF levels was 268.43±30.17 ng/ml in study group and 110.96±56.5 ng/ml in control group; this level was found not only raised in patients of AMI but were also statistically significant when compared with control group (p=<0.01).
  
  
  CONCLUSIONS
  TC, LDL-c, VLDL-c, TG and SF levels were raised in patients of AMI and found to be statistically significant; while HDL-c levels were reduced in such patients and is also statistically significant. It can be concluded that there exists an association in lipid profile and SF with AMI therefore dyslipidemia and raised SF levels are the features of AMI.
authors.affiliation: Post Graduate Student, Department of Biochemistry, Subharti Medical College, Swami Vivakan and Subharti University , Meerut, India .
authors.lastname: Shipra
authors.affiliation: Professor, Department of Biochemistry, Subharti Medical College, Swami Vivakan and Subharti University , Meerut, India .
authors.forename: Bharat Kumar
authors.initials: BK
authors.lastname: Gupta
authors.affiliation: Associate Professor, Department of Pathology, Muzaffarnagar Medical College , Muzaffarnagar, India .
authors.forename: Ranjan
authors.initials: R
authors.lastname: Solanki
authors.affiliation: Reader, Department of Community Dentistry, Teerthankar Dental College , Moradabad, India .
authors.forename: Himanshu
authors.initials: H
authors.lastname: Punia
authors.affiliation: Post Graduate Student, Department of Biochemistry, Subharti Medical College, Swami Vivakan and Subharti University , Meerut, India .
authors.forename: Vibhuti
authors.initials: V
authors.lastname: Agarwal
authors.affiliation: Assistant Professor, Department of Biochemistry, Subharti Medical College, Swami Vivakan and Subharti University , Meerut, India .
authors.forename: Jaskiran
authors.initials: J
authors.lastname: Kaur
authors.affiliation: Assistant Professor, Department of Biochemistry, Subharti Medical College, Swami Vivakan and Subharti University , Meerut, India .
authors.forename: Ashish
authors.initials: A
authors.lastname: Shukla
keywords: Acute myocardial infarction; Indian population; Lipid profile; Serum ferritin