title: Clinical implications of the obese-asthma phenotypes.
abstract: The concomitant increase in obesity and asthma in recent years has led to the classification of two obese-asthma phenotypes, characterized by the age of asthma onset and atopy. Asthma tends to be more severe, harder to control, and more resistant to standard medications among members of these two groups. Because of the limited effectiveness of inhaled corticosteroids, dietary changes and weight loss measures must be considered in the management of these patients. Furthermore, comorbidities such as depression and obstructive sleep apnea must be addressed to provide optimal care for this group of difficult-to-control asthmatics.
authors.affiliation: North Shore-Long Island Jewish Health System, Division of Allergy and Immunology, Hofstra School of Medicine, 865 Northern Boulevard, Suite 101, Great Neck, NY 11021, USA.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Diaz
authors.affiliation: North Shore-Long Island Jewish Health System, Division of Allergy and Immunology, Hofstra School of Medicine, 865 Northern Boulevard, Suite 101, Great Neck, NY 11021, USA. Electronic address: sfarzan@nshs.edu.
authors.forename: Sherry
authors.initials: S
authors.lastname: Farzan
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001249:Asthma / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*; D002648:Child; D003863:Depression / Q000453:epidemiology; D004032:Diet; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D009765:Obesity / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*; D010641:Phenotype; D015995:Prevalence; D020181:Sleep Apnea, Obstructive / Q000453:epidemiology
chemical_list: D000305:Adrenal Cortex Hormones; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors
keywords: Asthma; Body mass index; Obesity; Phenotypes