title: Periodontal responses to augmented corticotomy with collagen membrane application during orthodontic buccal tipping in dogs.
abstract: This prospective randomized split-mouth study was performed to examine the effects of absorbable collagen membrane (ACM) application in augmented corticotomy using deproteinized bovine bone mineral (DBBM), during orthodontic buccal tipping movement in the dog. After buccal circumscribing corticotomy and DBBM grafting into the decorticated area, flaps were repositioned and sutured on control sides. ACM was overlaid and secured with membrane tacks, on test sides only, and the flaps were repositioned and sutured. Closed coil springs were used to apply 200 g orthodontic force in the buccolingual direction on the second and third premolars, immediately after primary flap closure. The buccal tipping angles were 31.19 ± 14.60° and 28.12 ± 11.48° on the control and test sides, respectively. A mean of 79.5 ± 16.0% of the buccal bone wall was replaced by new bone on the control side, and on the test side 78.9 ± 19.5% was replaced. ACM application promoted an even bone surface. In conclusion, ACM application in augmented corticotomy using DBBM might stimulate periodontal tissue reestablishment, which is useful for rapid orthodontic treatment or guided bone regeneration. In particular, ACM could control the formation of mesenchymal matrix, facilitating an even bone surface.
authors.affiliation: Department of Periodontology, School of Dentistry, Kyung Hee University, No. 1, Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Republic of Korea ; Department of Oral and Maxillofacial Pathology and Research Center for Tooth and Periodontal Regeneration (MRC), School of Dentistry, Kyung Hee University, Seoul 130-701, Republic of Korea.
authors.forename: Dong-Yeol
authors.identifier: 0000-0001-7922-2754
authors.initials: DY
authors.lastname: Lee
authors.affiliation: Department of Orthodontics, School of Dentistry, Kyung Hee University, No. 1, Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Republic of Korea.
authors.forename: Hyo-Won
authors.identifier: 0000-0002-4872-7095
authors.initials: HW
authors.lastname: Ahn
authors.affiliation: Department of Periodontology, School of Dentistry, Kyung Hee University, No. 1, Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Republic of Korea.
authors.forename: Yeek
authors.initials: Y
authors.lastname: Herr
authors.affiliation: Department of Periodontology, School of Dentistry, Kyung Hee University, No. 1, Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Republic of Korea.
authors.forename: Young-Hyuk
authors.initials: YH
authors.lastname: Kwon
authors.affiliation: Department of Orthodontics, School of Dentistry, Kyung Hee University, No. 1, Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Republic of Korea.
authors.forename: Seong-Hun
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Department of Oral and Maxillofacial Pathology and Research Center for Tooth and Periodontal Regeneration (MRC), School of Dentistry, Kyung Hee University, Seoul 130-701, Republic of Korea.
authors.forename: Eun-Cheol
authors.initials: EC
authors.lastname: Kim
mesh_terms: D000818:Animals; D002417:Cattle; D003094:Collagen / Q000494:pharmacology*; D004285:Dogs; D008297:Male; D008334:Mandible / Q000187:drug effects / Q000601:surgery; D008437:Maxilla / Q000187:drug effects / Q000601:surgery; D008567:Membranes, Artificial; D009055:Mouth / Q000187:drug effects* / Q000601:surgery*; D009970:Orthodontics / Q000379:methods*; D010012:Osteogenesis / Q000187:drug effects; D010519:Periodontium / Q000473:pathology*
chemical_list: D008567:Membranes, Artificial; D003094:Collagen