title: Anti-platelet drugs in patients with femoral neck fractures undergoing cemented hip hemiarthroplasty surgery. A study of complications and mortality.
abstract: OBJECTIVE
  To assess complications and factors predicting one-year mortality in patients on antiplatelet agents presenting with femoral neck fractures undergoing hip hemiarthroplasty surgery.
  
  
  METHODS
  A review was made on 50 patients on preoperative antiplatelet agents and 83 patients without preoperative antiplatelet agents. Patients in both groups were treated with cemented hip hemiarthroplasty. A statistical comparison was performed using epidemiological data, comorbidities, mental state, complications and mortality. There was no lost to follow-up.
  
  
  RESULTS
  The one-year mortality was 20.3%. In patients without preoperative antiplatelet agents it was 14.4% and in patients with preoperative antiplatelet agents was 30%. Age, ASA grade, number of comorbidities and antiplatelet agent therapy were predictors of one-year mortality. The one-year mortality of patients on clopidogrel was 46.1%, versus 24.3% in patients on acetylsalicylic acid.
  
  
  CONCLUSIONS
  Patients with preoperative antiplatelet therapy were older and had greater number of comorbidities, ASA grade, delayed surgery, and a longer length of stay than patients without antiplatelet therapy. The one-year mortality was higher in patients with preoperative antiplatelet therapy.
authors.affiliation: Servicio de Cirugía Ortopédica, Hospital Universitario San Joan d'Alacant, Sant Joan d'Alacant, Alicante, España.
authors.forename: M
authors.initials: M
authors.lastname: Agudo Quiles
authors.affiliation: Servicio de Cirugía Ortopédica, Hospital Universitario San Joan d'Alacant, Sant Joan d'Alacant, Alicante, España. Electronic address: javisanz@coma.es.
authors.forename: J
authors.initials: J
authors.lastname: Sanz-Reig
authors.affiliation: Servicio de Cirugía Ortopédica, Hospital Universitario San Joan d'Alacant, Sant Joan d'Alacant, Alicante, España.
authors.forename: R
authors.initials: R
authors.lastname: Alcalá-Santaella Oria de Rueca
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip / Q000295:instrumentation / Q000379:methods; D001843:Bone Cements; D005260:Female; D005265:Femoral Neck Fractures / Q000401:mortality* / Q000601:surgery*; D005500:Follow-Up Studies; D062785:Hemiarthroplasty / Q000295:instrumentation / Q000379:methods; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects*; D011183:Postoperative Complications / Q000139:chemically induced* / Q000453:epidemiology; D057234:Preoperative Period; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D001843:Bone Cements; D010975:Platelet Aggregation Inhibitors
keywords: Antiplatelet agents; Complicaciones; Complications; Fractura de cadera; Hip fracture; Hip prostheses; Inhibidores de la agregación plaquetaria; Mortalidad; Mortality; Prótesis de cadera