title: Dual gold catalysis: synthesis of polycyclic compounds via C-H insertion of gold vinylidenes.
abstract: New and interesting polycyclic compounds have been synthesized from non-conjugated diyne systems by dual gold catalysis. A quaternary carbon center in the backbone and the accompanying Thorpe-Ingold effect enabled the unprecedented insertion of sp(3) and sp(2) CH bonds that for the first time were incorporated within the backbone of the diyne system and allowed the construction of complex polycyclic carbon scaffolds inaccessible by previous approaches in which the CH bonds for the insertion were situated at the other end of the alkyne.
authors.affiliation: Organisch-Chemisches Institut, Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg (Germany), Fax: (+49) 6221-54-4205.
authors.forename: Marcel
authors.initials: M
authors.lastname: Wieteck
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Tokimizu
authors.forename: Matthias
authors.initials: M
authors.lastname: Rudolph
authors.forename: Frank
authors.initials: F
authors.lastname: Rominger
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Ohno
authors.forename: Nobutaka
authors.initials: N
authors.lastname: Fujii
authors.forename: A Stephen K
authors.initials: AS
authors.lastname: Hashmi
mesh_terms: D000480:Alkynes / Q000737:chemistry; D002384:Catalysis; D006046:Gold / Q000737:chemistry*; D011083:Polycyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000480:Alkynes; D011083:Polycyclic Compounds; D006046:Gold
keywords: CH insertion; alkynes; gold; polycycles; vinylidene ligands