title: Total urinary hydroxyproline excretion in diabetics before and after hypophysectomy and after growth hormone in adult hypopituitarism.
abstract: Total urinary excretion of hydroxyproline has been found to be significantly decreased in adult diabetics and was increased after hypophysectomy for diabetic retinopathy. There was no change in hydroxyproline excretion after the administration of 53 mg. of human growth hormone to one patient with hypopituitarism over a 4 day period.
authors.forename: Gianni
authors.initials: G
authors.lastname: Bonadonna
authors.forename: Martin
authors.initials: M
authors.lastname: Sonenberg
authors.forename: Mario J
authors.initials: MJ
authors.lastname: Merlino
mesh_terms: D000328:Adult; D003920:Diabetes Mellitus / Q000503:physiopathology* / Q000601:surgery* / Q000652:urine*; D003930:Diabetic Retinopathy / Q000601:surgery*; D005260:Female; D013006:Growth Hormone; D019382:Human Growth Hormone / Q000627:therapeutic use*; D006801:Humans; D006909:Hydroxyproline / Q000378:metabolism* / Q000652:urine*; D007016:Hypophysectomy; D007018:Hypopituitarism / Q000188:drug therapy* / Q000652:urine*; D008297:Male; D008875:Middle Aged
chemical_list: D019382:Human Growth Hormone; D013006:Growth Hormone; D006909:Hydroxyproline