title: Bioconjugated gold nanoparticles accelerate the growth of new blood vessels through redox signaling.
abstract: We have designed and developed novel pro-angiogenic bio-synthesized gold nanoconjugates (b-Au-HP) that make new blood vessels, as observed by several in vitro and in vivo assays, suggesting their future potential applications in alternative treatment strategies for wound healing, cardiovascular diseases (CVD) and ischemic diseases using a nanomedicine approach.
authors.affiliation: Biomaterials Group, CSIR-Indian Institute of Chemical Technology, Uppal Road, Tarnaka, Hyderabad - 500007, India. crpatra@iict.res.in patra.chitta@gmail.com.
authors.forename: Susheel Kumar
authors.initials: SK
authors.lastname: Nethi
authors.forename: Sudip
authors.initials: S
authors.lastname: Mukherjee
authors.forename: Vimal
authors.initials: V
authors.lastname: Veeriah
authors.forename: Ayan Kumar
authors.initials: AK
authors.lastname: Barui
authors.forename: Suvro
authors.initials: S
authors.lastname: Chatterjee
authors.forename: Chitta Ranjan
authors.initials: CR
authors.lastname: Patra
mesh_terms: D000818:Animals; D002460:Cell Line; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D002642:Chick Embryo; D002712:Chlorides / Q000737:chemistry; D042783:Endothelial Cells / Q000187:drug effects / Q000502:physiology; D006046:Gold / Q000737:chemistry / Q000494:pharmacology*; D017612:Gold Compounds / Q000737:chemistry; D055772:Green Chemistry Technology; D032063:Hamelia; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry; D058726:Nanoconjugates / Q000737:chemistry; D018919:Neovascularization, Physiologic / Q000187:drug effects*; D010084:Oxidation-Reduction; D010936:Plant Extracts / Q000737:chemistry; D018515:Plant Leaves; D015398:Signal Transduction; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D002712:Chlorides; D017612:Gold Compounds; D058726:Nanoconjugates; D010936:Plant Extracts; D006046:Gold; C024568:gold tetrachloride, acid