title: Oral cavity squamous cell carcinoma--an overview.
abstract: Inhaled or chewed tobacco is equally addictive and harmful and used daily by over 1 billion people. In addition to increased rates of coronary artery disease, stroke, peripheral vascular disease, congestive heart failure, chronic obstructive pulmonary disease and lung cancers, tobacco is the leading preventable cause of oral cavity squamous cell carcinoma. In addition to tobacco, consumption and abuse of alcohol, and betel nut quid significantly contribute to the burden of oral cavity squamous cell carcinoma. Dental visits are excellent opportunities to identify primary lesions in the oral cavity. This review highlights relevant anatomy, epidemiology, pathogenesis, evaluation and treatment options for oral cavity squamous cell carcinoma.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of North Carolina Memorial Hospitals, 170 Manning Dr., Ground Floor Physician Office Building, CB#7070, Chapel Hill, NC 27599, USA; Tel: 919-966-6484; Fax: 919-966-7941; e-mail: kimplead@med.unc.edu.
authors.forename: Adam J
authors.initials: AJ
authors.lastname: Kimple
authors.forename: Chris M
authors.initials: CM
authors.lastname: Welch
authors.forename: Jose P
authors.initials: JP
authors.lastname: Zevallos
authors.forename: Samip N
authors.initials: SN
authors.lastname: Patel