title: Hybrid hybridomas and the production of bi-specific monoclonal antibodies.
abstract: Cell fusion techniques can now be used to generate antibodies with two different specificities. Here Cesar Milstein and A. C. Cuello discuss the theoretical basis of the method they have devised and its first applications in histochemistry and immunoassay.
authors.affiliation: Medical Research Council, Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK.
authors.forename: C
authors.initials: C
authors.lastname: Milstein
authors.forename: A C
authors.initials: AC
authors.lastname: Cuello