title: Long term survival with thoracoscopic versus open lobectomy: propensity matched comparative analysis using SEER-Medicare database.
abstract: OBJECTIVE
  To compare long term survival after minimally invasive lobectomy and thoracotomy lobectomy.
  
  
  METHODS
  Propensity matched analysis.
  
  
  METHODS
  Surveillance, Epidemiology and End Results (SEER)-Medicare database.
  
  
  METHODS
  All patients with lung cancer from 2007 to 2009 undergoing lobectomy.
  
  
  METHODS
  Influence of less invasive thoracoscopic surgery on overall survival, disease-free survival, and cancer specific survival.
  
  
  RESULTS
  From 2007 to 2009, 6008 patients undergoing lobectomy were identified (n=4715 (78%) thoracotomy). The median age of the entire cohort was 74 (interquartile range 70-78) years. The median length of follow-up for entire group was 40 months. In a matched analysis of 1195 patients in each treatment category, no statistical differences in three year overall survival, disease-free survival, or cancer specific survival were found between the groups (overall survival: 70.6% v 68.1%, P=0.55; disease-free survival: 86.2% v 85.4%, P=0.46; cancer specific survival: 92% v 89.5%, P=0.05).
  
  
  CONCLUSIONS
  This propensity matched analysis showed that patients undergoing thoracoscopic lobectomy had similar overall, cancer specific, and disease-free survival compared with patients undergoing thoracotomy lobectomy. Thoracoscopic techniques do not seem to compromise these measures of outcome after lobectomy.
authors.affiliation: Department of Health Policy and Research, Patient Centered Comparative Effectiveness Program, New York Presbyterian Hospital-Weill Cornell Medical College, New York, NY 10065, USA Department of Cardiothoracic Surgery, New York Presbyterian Hospital-Weill Cornell Medical College, New York, NY 10065, USA pas2022@med.cornell.edu.
authors.forename: Subroto
authors.initials: S
authors.lastname: Paul
authors.affiliation: Department of Health Policy and Research, Patient Centered Comparative Effectiveness Program, New York Presbyterian Hospital-Weill Cornell Medical College, New York, NY 10065, USA.
authors.forename: Abby J
authors.initials: AJ
authors.lastname: Isaacs
authors.affiliation: Clinical Operational Research Unit, University College London, London, UK.
authors.forename: Tom
authors.initials: T
authors.lastname: Treasure
authors.affiliation: Department of Cardiothoracic Surgery, New York Presbyterian Hospital-Weill Cornell Medical College, New York, NY 10065, USA.
authors.forename: Nasser K
authors.initials: NK
authors.lastname: Altorki
authors.affiliation: Department of Health Policy and Research, Patient Centered Comparative Effectiveness Program, New York Presbyterian Hospital-Weill Cornell Medical College, New York, NY 10065, USA Department of Cardiothoracic Surgery, New York Presbyterian Hospital-Weill Cornell Medical College, New York, NY 10065, USA.
authors.forename: Art
authors.initials: A
authors.lastname: Sedrakyan
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D016208:Databases, Factual; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D008175:Lung Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D008297:Male; D006278:Medicare; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D011013:Pneumonectomy / Q000379:methods* / Q000401:mortality; D011183:Postoperative Complications / Q000401:mortality / Q000503:physiopathology; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D018426:SEER Program; D016019:Survival Analysis; D013906:Thoracoscopy / Q000379:methods / Q000401:mortality; D013908:Thoracotomy / Q000379:methods / Q000401:mortality; D013997:Time Factors; D016896:Treatment Outcome; D014481:United States