title: Cardiovascular risk assessment in kidney transplantation.
abstract: Cardiovascular disease (CVD) remains the most common cause of death after kidney transplantation worldwide, with the highest event rate in the early postoperative period. In an attempt to address this issue, screening for CVD prior to transplant is common, but the clinical utility of screening asymptomatic transplant candidates remains unclear. A large degree of variation exists among both transplant center practice patterns and clinical practice guidelines regarding who should be screened, and opinions are based on mixed observational data with great potential for bias. In this review, we discuss the potential risks, benefits, and evidence for screening for CVD in kidney transplant candidates, and also the next steps to better evaluate and treat asymptomatic kidney transplant candidates.
authors.affiliation: 1] Division of Nephrology, Hennepin County Medical Center, Minneapolis, Minnesota, USA [2] University of Minnesota Medical School, Duluth, Minnesota, USA.
authors.forename: Allyson
authors.initials: A
authors.lastname: Hart
authors.affiliation: Department of Medicine, Division of Nephrology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Weir
authors.affiliation: 1] Division of Nephrology, Hennepin County Medical Center, Minneapolis, Minnesota, USA [2] University of Minnesota Medical School, Duluth, Minnesota, USA.
authors.forename: Bertram L
authors.initials: BL
authors.lastname: Kasiske
mesh_terms: D058070:Asymptomatic Diseases; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000150:complications / Q000175:diagnosis* / Q000601:surgery*; D003362:Cost-Benefit Analysis; D005080:Exercise Test; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D009203:Myocardial Infarction / Q000209:etiology / Q000517:prevention & control*; D062645:Percutaneous Coronary Intervention; D011237:Predictive Value of Tests; D051436:Renal Insufficiency, Chronic / Q000601:surgery*; D018570:Risk Assessment; D012307:Risk Factors; D014850:Waiting Lists