title: Stereotactic radiotherapy in epithelial ovarian cancer brain metastases patients.
abstract: BACKGROUND
  In this report we present the results of the retrospective (survival and classification) analyses of possible prognostic factors prolonging survival in epithelial ovarian cancer brain metastases patients after stereotactic radiotherapy. We focus on a wide range of available predictors to establish survival in patients with a good health status and no more than three lesions.
  
  
  METHODS
  Two parallel statistical methods in survival analysis were used: classical and Bayesian methods to verify statistical results. To display the predicted and posterior survivals, classification trees were built.
  
  
  RESULTS
  From the initial set of prognostic factors, only four were established as statistically significant in multivariate regression. They were: survival to metastases to brain after epithelial ovarian cancer diagnosis, number of metastases at diagnosis, central nervous system radiotherapy prior to stereotactic radiotherapy, and interval to stereotactic radiotherapy after metastases diagnosis.
  
  
  CONCLUSIONS
  When considering evidence-based standards of treatment of patients suffering from epithelial ovarian cancer brain metastases, the established clinical factors are suggested to be prognostic.
authors.forename: Agata
authors.initials: A
authors.lastname: Celejewska
authors.forename: Andrzej
authors.initials: A
authors.lastname: Tukiendorf
authors.forename: Leszek
authors.initials: L
authors.lastname: Miszczyk
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Składowski
authors.forename: Jerzy
authors.initials: J
authors.lastname: Wydmański
authors.forename: Krystyna
authors.initials: K
authors.lastname: Trela-Janus
mesh_terms: D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D000077216:Carcinoma, Ovarian Epithelial; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D060787:Neoplasm Grading; D009367:Neoplasm Staging; D009375:Neoplasms, Glandular and Epithelial / Q000175:diagnosis / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D011379:Prognosis; D016634:Radiosurgery; D016896:Treatment Outcome