title: Antigen recognition by T lymphocytes.
abstract: Many questions remain about the mechanisms of antigen recognition by T cells. Is antigen processing an absolute requirement for recognition by helper T cells? Does processing affect those areas of the antigen which associate with class II major histocompatibility complex (MHC) molecules (la antigens) or those which associate with T cell receptors or both? Where in the antigen-presenting cell (APC) does processing occur, and where does processed antigen associate with la? These questions were posed and discussed at a recent meeting on the immunology of proteins and peptides.
authors.affiliation: Peter Cresswell is at the Department of Microbiology and Immunology, Duke University Medical Center, Durham, NC 27710, USA.
authors.forename: P
authors.initials: P
authors.lastname: Cresswell