title: [Virus infections are important in acute asthma exacerbations].
abstract: Upper respiratory tract infections with common virusses is the most frequent cause of asthma exacerbations. Numerous defects in both epithelial function, pathogen recognition and innate immune signalling has been demonstrated in patients with asthma. The subject of this review is these recent findings and the potential therapeutic targets that are being identified.
authors.affiliation: Lungemedicinsk Forskningsenhed, Lungemedicinsk Afdeling L, Bispebjerg Hospital, Bispebjerg Bakke 23, 2400 København NV. E-mail: asgerbg@gmail.com.
authors.forename: Asger
authors.initials: A
authors.lastname: Bjerregaard
authors.forename: Vibeke
authors.initials: V
authors.lastname: Backer
authors.forename: Celeste
authors.initials: C
authors.lastname: Porsbjerg
mesh_terms: D000208:Acute Disease; D001249:Asthma / Q000150:complications / Q000503:physiopathology / Q000821:virology*; D018450:Disease Progression; D006801:Humans; D007372:Interferons / Q000502:physiology; D007378:Interleukins / Q000502:physiology; D012141:Respiratory Tract Infections / Q000821:virology*; D012229:Rhinovirus / Q000502:physiology*
chemical_list: D007378:Interleukins; D007372:Interferons