title: A temperature microsensor for measuring laser-induced heating in gold nanorods.
abstract: Measuring temperature is an extensively explored field of analysis, but measuring a temperature change in a nanoparticle is a new challenge. Here, a microsensor is configured to measure temperature changes in gold nanorods in solution upon laser irradiation. The device consists of a silicon wafer coated with silicon nitride in which a microfabricated resistance temperature detector was embedded and attached to a digital multimeter. A polydimethylsiloxane mold served as a microcontainer for the sample attached on top of the silicon membrane. This enables laser irradiation of the gold nanorods and subsequent measurement of temperature changes. The results showed a temperature increase of 8 to 10 °C and good correlation with theoretical calculations and bulk sample direct temperature measurements. These results demonstrate the suitability of this simple temperature microsensor for determining laser-induced heating profiles of metallic nanomaterials; such measurements will be essential for optimizing therapeutic and catalytic applications.
authors.affiliation: Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, EB III, Campus Box 7115, Raleigh, NC, 27695, USA.
authors.forename: Dennis B
authors.initials: DB
authors.lastname: Pacardo
authors.forename: Bhanu
authors.initials: B
authors.lastname: Neupane
authors.forename: Gufeng
authors.initials: G
authors.lastname: Wang
authors.forename: Zhen
authors.initials: Z
authors.lastname: Gu
authors.forename: Glenn M
authors.initials: GM
authors.lastname: Walker
authors.forename: Frances S
authors.initials: FS
authors.lastname: Ligler
mesh_terms: D002623:Chemistry Techniques, Analytical / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D006046:Gold; D006361:Heating; D006358:Hot Temperature; D007834:Lasers; D055616:Microtechnology; D043942:Nanotubes / Q000032:analysis*
chemical_list: D006046:Gold