title: Endoscopic imaging of the vermiform appendix (with video).
abstract: BACKGROUND
  Chronic appendicitis may be detected in as many as 10% of patients with right lower quadrant pain. Although the appendiceal orifice is easily identified during colonoscopy, its lumen has not been investigated so far.
  
  
  OBJECTIVE
  To determine the feasibility of endoscopic appendix imaging to identify features of chronic appendicitis in patients with recurrent right lower quadrant pain.
  
  
  METHODS
  Prospective, proof-of-concept study.
  
  
  METHODS
  University-based tertiary referral hospital.
  
  
  METHODS
  Colonoscopy scheduled because of right lower quadrant pain.
  
  
  METHODS
  First, the appendix orifice was cannulated with a guidewire and a Jagtome. Next fluoroscopic imaging was performed by injection of contrast agent into the appendix orifice, and then a SpyGlass endoscope was inserted for imaging of the appendiceal mucosa and for biopsy. Patients were monitored 3 hours after investigation, with follow-up at 4 weeks.
  
  
  METHODS
  Cannulation rate.
  
  
  RESULTS
  Thirteen patients were included. Endoscopic imaging of the appendix was successful in 9 of 13 patients (69%). In 10 patients, a guidewire was placed; in 7 patients, biopsy specimens were taken, revealing histological signs of inflammation in 5. In 4 patients, visible fecoliths were removed by flushing. All patients were discharged on the same day. No adverse events occurred. Three patients reported resolution of pain at follow-up. One patient with strictures at appendicoscopy underwent surgical appendectomy. Histology confirmed the findings of chronic appendicitis with fibrosis.
  
  
  CONCLUSIONS
  Patient number limits power for analysis.
  
  
  CONCLUSIONS
  Endoscopic imaging of the appendix is feasible, safe, and clinically useful in patients with suspected chronic appendicitis.
authors.affiliation: Department of Medicine 3, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.
authors.forename: Arnulf
authors.initials: A
authors.lastname: Ferlitsch
authors.affiliation: Department of Medicine 3, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.
authors.forename: Andreas
authors.initials: A
authors.lastname: Puespoek
authors.affiliation: Department of Medicine 3, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.
authors.forename: Christoph
authors.initials: C
authors.lastname: Gasche
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000328:Adult; D001064:Appendicitis / Q000150:complications / Q000473:pathology*; D001065:Appendix / Q000473:pathology*; D001706:Biopsy; D002404:Catheterization; D002908:Chronic Disease; D003113:Colonoscopy / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D005471:Fluoroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D061848:Optical Imaging; D011446:Prospective Studies; D055815:Young Adult