title: Age and gender may influence the results of Roux-en-Y gastric bypass? Metabolic syndrome parameters.
abstract: BACKGROUND
  Severe obesity affects the body favoring the development of serious diseases, including hypertension, diabetes mellitus, atherosclerosis and non alcoholic fatty liver disease. Bariatric procedures increased in Brazil in the last decade.
  
  
  OBJECTIVE
  The purpose of this study was to verify if gender and age in date of procedure resulted significant differences in metabolic syndrome parameters after surgery.
  
  
  METHODS
  The study involved 205 medical records of adult patients undergoing Roux-en-Y gastric bypass, stratified by gender and age groups and followed one year by a multidisciplinary team.
  
  
  RESULTS
  It was observed significant decrease in body mass index, fasting glucose and insulin at all ages and both genders. Lipid profile showed significant improvements except high density lipoprotein cholesterol. Ectopic fat in the liver has decreased after 6 months in patients classified with steatosis at baseline. Patients classified as hypertensive blood pressure levels decreased 6 months after surgical intervention.
  
  
  CONCLUSIONS
  Roux-en-Y gastric bypass proved to be an important tool in remission of metabolic syndrome parameters. The reduction of body mass accompanied to decrease in insulin resistance resulted in lower prevalence of comorbidities associated with obesity. The benefits were similar and extended both genders and all age groups between 18 and 65 years old.
authors.affiliation: Programa de Pós-Graduação Interdisciplinar de Ciências da Saúde, Universidade Federal de São Paulo - UNIFESP, Santos, SP, Brasil.
authors.forename: Stephan Garcia
authors.initials: SG
authors.lastname: Andrade-Silva
authors.affiliation: Programa de Pós-Graduação Interdisciplinar de Ciências da Saúde, Universidade Federal de São Paulo - UNIFESP, Santos, SP, Brasil.
authors.forename: Danielle Arisa
authors.initials: DA
authors.lastname: Caranti
authors.affiliation: CliLeal - Clínica Médica e Cirurgia Geral, Santos, SP, Brasil.
authors.forename: José Afonso
authors.initials: JA
authors.lastname: Sallet
authors.affiliation: Grupo de Estudos da Obesidade - GEO, Universidade Federal de São Paulo - UNIFESP, Santos, SP, Brasil.
authors.forename: Lucas Pedroso Fernandes Ferreira
authors.initials: LP
authors.lastname: Leal
authors.affiliation: CliLeal - Clínica Médica e Cirurgia Geral, Santos, SP, Brasil.
authors.forename: Antonio Joaquim Ferreira
authors.initials: AJ
authors.lastname: Leal
authors.affiliation: Programa de Pós-Graduação Interdisciplinar de Ciências da Saúde, Universidade Federal de São Paulo - UNIFESP, Santos, SP, Brasil.
authors.forename: Ana Raimunda
authors.initials: AR
authors.lastname: Dâmaso
mesh_terms: D000328:Adult; D000367:Age Factors; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D015390:Gastric Bypass; D006801:Humans; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000097:blood / Q000150:complications / Q000601:surgery*; D012189:Retrospective Studies; D012737:Sex Factors; D016896:Treatment Outcome; D055815:Young Adult