title: Clinical characteristics of Staphylococcus epidermidis: a systematic review.
abstract: Staphylococci are known as clustering Gram-positive cocci, nonmotile, non-spore forming facultatively anaerobic that classified in two main groups, coagulase-positive and coagulase-negative. Staphylococcus epidermidis with the highest percentage has the prominent role among coagulase-negative Staphylococci that is the most important reason of clinical infections. Due to various virulence factors and unique features, this microorganism is respected as a common cause of nosocomial infections. Because of potential ability in biofilm formation and colonization in different surfaces, also using of medical implant devices in immunocompromised and hospitalized patients the related infections have been increased. In recent decades the clinical importance and the emergence of methicillin-resistant Staphylococcus epidermidis strains have created many challenges in the treatment process.
authors.affiliation: Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Amirmorteza Ebrahimzadeh
authors.initials: AE
authors.lastname: Namvar
authors.affiliation: Department of Microbiology & Biochemistry, Islamic Azad University Falavarjan Branch, Isfahan, Iran.
authors.forename: Sara
authors.initials: S
authors.lastname: Bastarahang
authors.affiliation: Department of Microbiology & Biochemistry, Islamic Azad University Falavarjan Branch, Isfahan, Iran.
authors.forename: Niloufar
authors.initials: N
authors.lastname: Abbasi
authors.affiliation: Department of Microbiology & Biochemistry, Islamic Azad University Falavarjan Branch, Isfahan, Iran.
authors.forename: Ghazaleh Sheikhi
authors.initials: GS
authors.lastname: Ghehi
authors.affiliation: Department of Microbiology & Biochemistry, Islamic Azad University Falavarjan Branch, Isfahan, Iran.
authors.forename: Sara
authors.initials: S
authors.lastname: Farhadbakhtiarian
authors.affiliation: Department of Microbiology & Biochemistry, Islamic Azad University Falavarjan Branch, Isfahan, Iran.
authors.forename: Parastoo
authors.initials: P
authors.lastname: Arezi
authors.affiliation: Department of Microbiology & Biochemistry, Islamic Azad University Falavarjan Branch, Isfahan, Iran.
authors.forename: Mahsa
authors.initials: M
authors.lastname: Hosseini
authors.affiliation: Department of Microbiology & Biochemistry, Islamic Azad University Falavarjan Branch, Isfahan, Iran.
authors.forename: Sholeh Zaeemi
authors.initials: SZ
authors.lastname: Baravati
authors.affiliation: Department of Microbiology & Biochemistry, Islamic Azad University Falavarjan Branch, Isfahan, Iran.
authors.forename: Zahra
authors.initials: Z
authors.lastname: Jokar
authors.affiliation: Department of Microbiology & Biochemistry, Islamic Azad University Falavarjan Branch, Isfahan, Iran.
authors.forename: Sara Ganji
authors.initials: SG
authors.lastname: Chermahin
keywords: Staphylococcus epidermidis; coagulase-negative staphylococci; nosocomial infections; virulence factors