title: Modifications of the chemical structure of phenolics differentially affect physiological activities in pulvinar cells of Mimosa pudica L. I. Multimode effect on early membrane events.
abstract: A study of the structure-activity relationship carried out on several benzoic acid-related phenolics indicates that this type of compounds hinders the osmocontractile reaction of pulvinar cells in the range of 0-100%. Tentatively, we tried to find a way that could explain this differential action. With this aim, the relationship between the inhibitory effect and important molecular physico-chemical parameters (namely lipophilicity and degree of dissociation) was drawn. In addition, the effect of a variety of these compounds was investigated on their capacity to modify the electrical transmembrane potential and induce modifications in proton fluxes. Finally, using plasma membrane vesicles purified from pulvinar tissues, we examined the effects of some selected compounds on the proton pump activity and catalytic activity of the plasma membrane H(+)-ATPase. Taken together, the results indicate that a modification of the molecular structure of phenolics may induce important variation in the activity of the compound on these early membrane events. Among the tested phenolics, salicylic acid (SA) and acetylsalicylic acid (ASA, aspirin) are of particuler note, as they showed atypical effects on the physiological processes studied.
authors.affiliation: IC2MP (Institut de Chimie des Milieux et des Matériaux de Poitiers), UMR CNRS 7285, Université de Poitiers, 4 rue Michel Brunet, TSA 51106, F-86073 Poitiers Cedex 9, France.
authors.forename: Françoise
authors.initials: F
authors.lastname: Rocher
authors.affiliation: Laboratoire EBI (Écologie et Biologie des Interactions), UMR CNRS 7267, Équipe SEVE (Sucres, Échanges Végétaux, Environnement), Université de Poitiers, 3 rue Jacques Fort, TSA 51106, F-86073 Poitiers Cedex 9, France. Electronic address: fabienne.dedaldechamp@univ-poitiers.fr.
authors.forename: Fabienne
authors.initials: F
authors.lastname: Dédaldéchamp
authors.affiliation: Laboratoire EBI (Écologie et Biologie des Interactions), UMR CNRS 7267, Équipe SEVE (Sucres, Échanges Végétaux, Environnement), Université de Poitiers, 3 rue Jacques Fort, TSA 51106, F-86073 Poitiers Cedex 9, France.
authors.forename: Saed
authors.initials: S
authors.lastname: Saeedi
authors.affiliation: Laboratoire EBI (Écologie et Biologie des Interactions), UMR CNRS 7267, Équipe SEVE (Sucres, Échanges Végétaux, Environnement), Université de Poitiers, 3 rue Jacques Fort, TSA 51106, F-86073 Poitiers Cedex 9, France.
authors.forename: Pierrette
authors.initials: P
authors.lastname: Fleurat-Lessard
authors.affiliation: IC2MP (Institut de Chimie des Milieux et des Matériaux de Poitiers), UMR CNRS 7285, Université de Poitiers, 4 rue Michel Brunet, TSA 51106, F-86073 Poitiers Cedex 9, France.
authors.forename: Jean-Francois
authors.initials: JF
authors.lastname: Chollet
authors.affiliation: Laboratoire EBI (Écologie et Biologie des Interactions), UMR CNRS 7267, Équipe SEVE (Sucres, Échanges Végétaux, Environnement), Université de Poitiers, 3 rue Jacques Fort, TSA 51106, F-86073 Poitiers Cedex 9, France.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Roblin
mesh_terms: D001241:Aspirin / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism*; D031298:Mimosa / Q000378:metabolism; D010636:Phenols / Q000378:metabolism; D006180:Proton-Translocating ATPases / Q000378:metabolism; D020649:Pulvinar / Q000378:metabolism*; D020156:Salicylic Acid / Q000378:metabolism
chemical_list: D010636:Phenols; D006180:Proton-Translocating ATPases; D020156:Salicylic Acid; D001241:Aspirin
keywords: Aspirin; H(+)-ATPase; Membrane potential; Mimosa pudica; Phenolics; Salicylic acid; Seismonasty