title: Comparative evaluation of antimicrobial activity of two root canal sealers: MTA Fillapex and AH 26.
abstract: OBJECTIVE
  Even after a complete root canal therapy, reinfection may occur as a result of incomplete seal and activation of residual bacteria. Thus, antimicrobial activity is an important characteristic of root canal sealers. MTA Fillapex is a newly developed MTA-based sealer. It has been subjected to various studies evaluating its physical and chemical properties. In this study, we aimed to compare the antimicrobial activity of this sealer to the commonly known widely accepted sealer, AH26.
  
  
  METHODS
  MTA Fillapex and AH 26 were exposed the bacterial suspension of Enterococcus faecalis, Escherichia coli, Streptococcus mutans, and Candida albicans after setting. After incubation and complete evaporation, BHI was added to microtubes. 24 hours later, the liquid content was placed in agar diffusion plate and bacterial count was performed. ANOVA followed by Tukey test, and t-Test were performed to analyze the data.
  
  
  RESULTS
  With regard to all four bacterial groups, the bacterial count was significantly lower in MTAFillapex group comparing to AH 26 group.
  
  
  CONCLUSIONS
  Newly developed MTA Fillapex sealer, has better antimicrobial properties in comparison to the widely accepted AH26 sealer.
authors.affiliation: Department of Endodontics, Faculty of Dentistry Dental Material Research Center Babol University of Medical Sciences, Babol, Iran:2 Department of Mycology and Parasitology Babol University of Medical Sciences, Babol, Iran:3 Department of Pedodontics, Faculty of Dentistry Dental Research Center Birjand University of Medical Sciences, Birjand, Iran - madani_z@yahoo.com.
authors.forename: Z S
authors.initials: ZS
authors.lastname: Madani
authors.forename: S A
authors.initials: SA
authors.lastname: Sefidgar
authors.forename: A
authors.initials: A
authors.lastname: Rashed Mohasel
authors.forename: E
authors.initials: E
authors.lastname: Zabihi
authors.forename: A
authors.initials: A
authors.lastname: Mesgarani
authors.forename: A
authors.initials: A
authors.lastname: Bijani
authors.forename: S S
authors.initials: SS
authors.lastname: Miri
mesh_terms: D017607:Aluminum Compounds / Q000494:pharmacology*; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001729:Bismuth / Q000494:pharmacology*; D017610:Calcium Compounds / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects*; D015169:Colony Count, Microbial; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D013293:Enterococcus faecalis / Q000187:drug effects*; D004853:Epoxy Resins / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects*; D006801:Humans; D010087:Oxides / Q000494:pharmacology*; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D017640:Silicates / Q000494:pharmacology*; D012834:Silver / Q000494:pharmacology*; D013295:Streptococcus mutans / Q000187:drug effects*; D014025:Titanium / Q000494:pharmacology*
chemical_list: D017607:Aluminum Compounds; D000890:Anti-Infective Agents; D017610:Calcium Compounds; D004338:Drug Combinations; D004853:Epoxy Resins; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate; D012834:Silver; C028044:epoxy resin AH-26; D014025:Titanium; D001729:Bismuth