title: [Clinical application of ROLL technique in non-breast diseases. Complementary use after PET-CT study].
abstract: OBJECTIVE
  The aim of this study was to evaluate the usefulness of ROLL technique (Radioguided Occult Lesion Localization) as a verification method of suspicious lesions not related to breast disease found in PET-CT studies.
  
  
  METHODS
  We retrospectively evaluated 9 patients diagnosed of cancer or with suspected tumor disease who showed hypermetabolic lymph nodes in (18)F-FDG PET-CT. Subjects underwent diagnostic testing for evaluation of treatment response in lymphoma (3), suspected recurrence in other tumors (3) or biopsy guide (3). The study group consisted of 4 women and 5 men, age range 25-72 years. ROLL technique was performed in surgically accessible lesions (supraclavicular region, lateral cervical, axillary and inguinal) with an intralesional injection of (99m)Tc-albumin macroaggregates guided by ultrasound the day before surgery. A scintigraphic study confirmed the focal tracer deposit and absence of skin contamination. During surgery, a gamma probe and portable gammacamera were used to locate lymph nodes.
  
  
  RESULTS
  Surgical localization of radiolabeled lymph nodes was achieved in all cases with minimally invasive surgery and few postoperative complications. Histological study resulted in five tumor involvement (3 lymphoma, 1 germ cell tumor and 1 neuroendocrine carcinoma) and confirmed the existence of four false-positives in PET-CT study (1 sarcoidosis and 3 reactive follicular hyperplasia).
  
  
  CONCLUSIONS
  The ROLL technique proved to be a useful and relatively simple method for the study of no breast lesions suspicious of malignancy in PET-CT study.
authors.affiliation: Servicio de Medicina Nuclear, Complejo Hospitalario Universitario de Badajoz, Badajoz, España. Electronic address: infantetorre@yahoo.com.
authors.forename: J R
authors.initials: JR
authors.lastname: Infante
authors.affiliation: Servicio de Medicina Nuclear, Complejo Hospitalario Universitario de Badajoz, Badajoz, España.
authors.forename: J I
authors.initials: JI
authors.lastname: Rayo
authors.affiliation: Servicio de Medicina Nuclear, Complejo Hospitalario Universitario de Badajoz, Badajoz, España.
authors.forename: J
authors.initials: J
authors.lastname: Serrano
authors.affiliation: Servicio de Medicina Nuclear, Complejo Hospitalario Universitario de Badajoz, Badajoz, España.
authors.forename: M L
authors.initials: ML
authors.lastname: Domínguez
authors.affiliation: Servicio de Medicina Nuclear, Complejo Hospitalario Universitario de Badajoz, Badajoz, España.
authors.forename: L
authors.initials: L
authors.lastname: García
authors.affiliation: Servicio de Medicina Nuclear, Complejo Hospitalario Universitario de Badajoz, Badajoz, España.
authors.forename: C
authors.initials: C
authors.lastname: Durán
authors.affiliation: Servicio de Medicina Nuclear, Complejo Hospitalario Universitario de Badajoz, Badajoz, España.
authors.forename: M
authors.initials: M
authors.lastname: Moreno
mesh_terms: D000328:Adult; D000368:Aged; D018278:Carcinoma, Neuroendocrine / Q000000981:diagnostic imaging / Q000556:secondary; D005260:Female; D006801:Humans; D061705:Image-Guided Biopsy / Q000379:methods*; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000000981:diagnostic imaging*; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging*; D008223:Lymphoma / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009373:Neoplasms, Germ Cell and Embryonal / Q000000981:diagnostic imaging / Q000556:secondary; D000072078:Positron Emission Tomography Computed Tomography; D011300:Preoperative Care; D019310:Pseudolymphoma / Q000000981:diagnostic imaging; D012008:Recurrence; D012189:Retrospective Studies; D012507:Sarcoidosis / Q000000981:diagnostic imaging
keywords: Cirugía radiodirigida; PET-CT; PET-TAC; ROLL; Radioguided surgery