title: Laser-assisted in situ keratomileusis for correction of astigmatism and increasing contact lens tolerance after penetrating keratoplasty.
abstract: OBJECTIVE
  To determine effectiveness of laser-assisted in situ keratomileusis (LASIK) in the treatment of astigmatism following penetrating keratoplasty (PK).
  
  
  METHODS
  We performed a retrospective review of medical records of patients who underwent LASIK following PK and had over 1 year of follow-up data.
  
  
  RESULTS
  Twenty-six patients (26 pairs of eyes) underwent LASIK following PK. Mean age of the patients at the time of LASIK was 40.7 years (range, 26 to 72 years). Following LASIK, the mean cylinder was reduced by 2.4 diopters and mean reduction of cylinder after LASIK was 65.4% from the preoperative values at the last follow-up visit. Uncorrected visual acuity became 20 / 50 or better in 69.2% of the eyes after LASIK. Best-corrected visual acuity became 20 / 50 or better in 73.1% of the eyes after LASIK. All of them were intolerable to contact lenses before LASIK. After LASIK, 6 pairs (23.1%) did not need to use contact lenses and 18 pairs (69.2%) were tolerable to using contact lenses or spectacles. There were no significant endothelial cell density changes 12 months after LASIK (p = 0.239).
  
  
  CONCLUSIONS
  LASIK is effective in the treatment of astigmatism following PK and increases contact lens and spectacle tolerance.
authors.affiliation: Department of Ophthalmology, Uijeongbu St. Mary's Hospital, The Catholic University of Korea College of Medicine, Uijeongbu, Korea. ; Hospital of 18th Fighter Wing, Republic of Korea Air Force, Korea.
authors.forename: Chang-Hyun
authors.initials: CH
authors.lastname: Park
authors.affiliation: Department of Ophthalmology, Uijeongbu St. Mary's Hospital, The Catholic University of Korea College of Medicine, Uijeongbu, Korea.
authors.forename: Su-Young
authors.initials: SY
authors.lastname: Kim
authors.affiliation: Department of Ophthalmology, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors.forename: Man-Soo
authors.initials: MS
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D001251:Astigmatism / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D003261:Contact Lenses / Q000706:statistics & numerical data; D019781:Corneal Topography; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D015948:Keratoplasty, Penetrating / Q000009:adverse effects*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012029:Refraction, Ocular / Q000502:physiology; D012189:Retrospective Studies; D015348:Vision, Binocular / Q000502:physiology; D014792:Visual Acuity / Q000502:physiology
keywords: Astigmatism; Laser in situ keratomileusis; Penetrating keratoplasty