title: Destination and source memory in Huntington's disease.
abstract: Destination memory refers to the recall of the destination of previously relayed information, and source memory refers to the recollection of the origin of received information. We compared both memory systems in Huntington's disease (HD) participants. For this, HD participants and healthy adults had to put 12 items in a black or a white box (destination task), and to extract another 12 items from a blue or a red box (source task). Afterwards, they had to decide in which box each item had previously been deposited (destination memory), and from which box each item had previously been extracted (source memory). HD participants showed poorer source as well as destination recall performance than healthy adults in the proposed tasks. Correlation analysis showed that destination recall was significantly correlated with episodic recall in HD participants. Destination memory impairment in HD participants seems to be considerably influenced by their episodic memory performance.
authors.affiliation: Research Unit on Cognitive and Affective Sciences, Department of Psychology, University of North of France, Lille, France.
authors.forename: Mohamad
authors.initials: M
authors.lastname: El Haj
authors.affiliation: UNAM University, Psychology Laboratory (EA 4638), University of Nantes and Angers, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Caillaud
authors.affiliation: UMR CNRS 6214, Inserm U1083, University of Angers, France.|Neurology Department, CHU of Angers, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Verny
authors.affiliation: Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, the Netherlands.
authors.forename: Luciano
authors.initials: L
authors.lastname: Fasotti
authors.affiliation: UNAM University, Psychology Laboratory (EA 4638), University of Nantes and Angers, France.|Neurology Department, CHU of Angers, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Allain
mesh_terms: D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006816:Huntington Disease / Q000523:psychology*; D008297:Male; D061212:Memory, Episodic; D011939:Mental Recall; D008875:Middle Aged; D009483:Neuropsychological Tests
keywords: Huntington's disease; destination memory; episodic memory; executive function; source memory