title: Ratiometric fluorescent scaffold giving discrete response towards iodide ion: a combined experimental and DFT study.
abstract: A novel ratiometric fluorescent receptor (Z)-2-(4-[diethylamino]-2-hydroxybenzylideneamino) pyridine-3-carbaldehyde (3) bearing one phenolic OH and one aldehyde group as recognition sites was synthesized and characterized. The anion recognition behaviour of receptor 3 was evaluated by various spectroscopic (UV-visible, fluorescence and (1) H nuclear magnetic resonance) methods and was validated by computational studies. The receptor showed fast response time, excellent selectivity and reproducibility towards iodide ion detection among the other surveyed anions, with a binding constant of 6.12 × 10(4)  M(-1) and a detection limit of 0.24 μM, thus confirming its potential applicability as a fluorescent sensor for iodide.
authors.affiliation: School of Chemical Sciences, North Maharashtra University, Jalgaon, 425001, Maharashtra, India.
authors.forename: Rahul
authors.initials: R
authors.lastname: Patil
authors.forename: Kundan
authors.initials: K
authors.lastname: Tayade
authors.forename: Suban K
authors.initials: SK
authors.lastname: Sahoo
authors.forename: Jasminder
authors.initials: J
authors.lastname: Singh
authors.forename: Narinder
authors.initials: N
authors.lastname: Singh
authors.forename: Dilip
authors.initials: D
authors.lastname: Hundiwale
authors.forename: Anil
authors.initials: A
authors.lastname: Kuwar
mesh_terms: D000631:Aminopyridines / Q000737:chemistry*; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D007454:Iodides / Q000032:analysis* / Q000737:chemistry; D057230:Limit of Detection; D008958:Models, Molecular; D011789:Quantum Theory; D012545:Schiff Bases / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet
chemical_list: C000598599:2-(4-(diethylamino)-2-hydroxybenzylideneamino)pyridine-3-carbaldehyde; D000631:Aminopyridines; D005456:Fluorescent Dyes; D007454:Iodides; D012545:Schiff Bases
keywords: DFT; iodide; molecular recognition; receptor 3