title: Functional and morphological changes after macular pucker surgery: an optical coherence tomography and microperimetric study.
abstract: OBJECTIVE
  To investigate the relationship among functional and morphological findings before and after macular pucker surgery.
  
  
  METHODS
  Thirty-eight eyes with idiopathic macular pucker that underwent 25-gauge vitrectomy and infracyanine green-assisted internal limiting membrane peeling were prospectively enrolled. Main outcome measures were best-corrected visual acuity (BCVA), spectral-domain optical coherence tomography findings and MP-1 microperimetry findings.
  
  
  RESULTS
  Mean BCVA improvement was 0.34 logMAR (p < 0.0001). Mean central retinal thickness (CRT) reduction was 50 µm (p = 0.0041). Mean retinal sensitivity improvement was 0.9. Patients with a greater improvement of postoperative BCVA showed worse baseline BCVA (p < 0.001), shorter final inner/outer segment (IS/OS) interruption length (p = 0.039) and thinner final CRT (p = 0.035). Furthermore, final BCVA was correlated with baseline IS/OS interruption length (p = 0.001).
  
  
  CONCLUSIONS
  Baseline BCVA, CRT and IS/OS integrity can be used to predict the functional outcomes after macular pucker surgery.
authors.affiliation: Medical and Biological Sciences - Ophthalmology, University of Udine, Udine, Italy.
authors.forename: Martina
authors.initials: M
authors.lastname: Santarelli
authors.forename: Daniele
authors.initials: D
authors.lastname: Veritti
authors.forename: Gloria
authors.initials: G
authors.lastname: Dal Mas
authors.forename: Paolo
authors.initials: P
authors.lastname: Lanzetta
mesh_terms: D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008266:Macula Lutea / Q000473:pathology* / Q000503:physiopathology* / Q000601:surgery; D008297:Male; D011184:Postoperative Period; D011446:Prospective Studies; D012167:Retinal Perforations / Q000473:pathology / Q000601:surgery*; D041623:Tomography, Optical Coherence / Q000379:methods*; D016896:Treatment Outcome; D058609:Visual Field Tests / Q000379:methods*; D014794:Visual Fields / Q000502:physiology*; D014821:Vitrectomy / Q000379:methods*