title: IncI1/ST113 and IncI1/ST114 conjugative plasmids carrying blaCTX-M-8 in Escherichia coli isolated from poultry in Brazil.
abstract: Extended-spectrum beta-lactamase-producing Escherichia coli isolated from poultry in Brazil showed blaCTX-M-8 gene. IS10 was found upstream of blaCTX-M-8, harbored on plasmids IncI1, ST113/ST114 subtypes. Genomic relationship revealed a heterogeneous E. coli population. The gene blaCTX-M-8 is established in South America in food-producing animals, which represent risk of dissemination for other countries.
authors.affiliation: School of Pharmaceutical Sciences of Ribeirão Preto-University of São Paulo (USP), Ribeirão Preto, SP, 14040-903, Brazil.
authors.forename: Joseane Cristina
authors.initials: JC
authors.lastname: Ferreira
authors.affiliation: School of Agricultural and Veterinary Sciences-São Paulo State University (UNESP), Jaboticabal, SP, 14884-900, Brazil.
authors.forename: Rafael Antonio Casarin
authors.initials: RA
authors.lastname: Penha Filho
authors.affiliation: School of Pharmaceutical Sciences of Ribeirão Preto-University of São Paulo (USP), Ribeirão Preto, SP, 14040-903, Brazil.
authors.forename: Leonardo Neves
authors.initials: LN
authors.lastname: Andrade
authors.affiliation: School of Agricultural and Veterinary Sciences-São Paulo State University (UNESP), Jaboticabal, SP, 14884-900, Brazil.
authors.forename: Angelo
authors.initials: A
authors.lastname: Berchieri
authors.affiliation: School of Pharmaceutical Sciences of Ribeirão Preto-University of São Paulo (USP), Ribeirão Preto, SP, 14040-903, Brazil. Electronic address: aldarini@fcfrp.usp.br.
authors.forename: Ana Lúcia Costa
authors.initials: AL
authors.lastname: Darini
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001938:Brazil; D002645:Chickens / Q000382:microbiology; D024881:Drug Resistance, Bacterial / Q000187:drug effects / Q000235:genetics; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification*; D029968:Escherichia coli Proteins; D008826:Microbial Sensitivity Tests; D058885:Multilocus Sequence Typing; D010802:Phylogeny; D010957:Plasmids; D011200:Poultry / Q000382:microbiology*; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D000900:Anti-Bacterial Agents; D029968:Escherichia coli Proteins; C000599759:blaCTX-M-8 protein, E coli; D001618:beta-Lactamases
keywords: CTX-M; Chickens; ESBL; Food-producing animals; pMLST