title: [Serious adverse effect of combined oral contraceptive pills among teenagers].
abstract: PubMed-search found studies investigating adverse effects of combined oral contraceptive pills (COC) among teenagers. Four studies found a small negative impact of COC on acquisition of bone mineral density. COC is associated with elevated risk of venous thrombotic events (VTE), especially during the first year of usage. VTE risk increases with EE dose and progestin of 3rd and 4th generation. There are several difficulties in studying COC use in teenagers: high dropout rates, ethical considerations and many different COC formulas.
authors.affiliation: Gynækologisk-Obstetrisk Afdeling G, Herlev Hospital, Herlev Ringvej 75, 2730 Herlev. E-mail: machny@dadlnet.dk.
authors.forename: Malin Chatarina
authors.initials: MC
authors.lastname: Nylander
authors.forename: Helle V
authors.initials: HV
authors.lastname: Clausen
mesh_terms: D000293:Adolescent; D015519:Bone Density / Q000187:drug effects*; D003277:Contraceptives, Oral, Combined / Q000008:administration & dosage / Q000009:adverse effects*; D004967:Estrogens / Q000008:administration & dosage / Q000009:adverse effects; D005260:Female; D006801:Humans; D011372:Progestins / Q000008:administration & dosage / Q000009:adverse effects; D012307:Risk Factors; D054556:Venous Thromboembolism / Q000139:chemically induced*; D055815:Young Adult
chemical_list: D003277:Contraceptives, Oral, Combined; D004967:Estrogens; D011372:Progestins