title: [Iron deficiency and digestive disorders].
abstract: Iron deficiency anemia still remains problematic worldwide. Iron deficiency without anemia is often undiagnosed. We reviewed, in this study, symptoms and syndromes associated with iron deficiency with or without anemia: fatigue, cognitive functions, restless legs syndrome, hair loss, and chronic heart failure. Iron is absorbed through the digestive tract. Hepcidin and ferroportin are the main proteins of iron regulation. Pathogenic micro-organisms or intestinal dysbiosis are suspected to influence iron absorption.
authors.affiliation: Pavillon F, hôpital E.-Herriot, place d'Arsonval, 69437 Lyon cedex 03, France; UFR Lyon-Est UCBL, domaine Rockefeller, 8, avenue Rockefeller, 69373 Lyon cedex 08, France. Electronic address: gregoire.cozon@chu-lyon.fr.
authors.forename: G J N
authors.initials: GJ
authors.lastname: Cozon
mesh_terms: D000505:Alopecia / Q000209:etiology; D018798:Anemia, Iron-Deficiency / Q000453:epidemiology / Q000209:etiology; D000818:Animals; D027682:Cation Transport Proteins / Q000502:physiology; D003072:Cognition Disorders / Q000209:etiology; D017079:Exercise Tolerance; D005221:Fatigue / Q000209:etiology; D006333:Heart Failure / Q000209:etiology; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000150:complications / Q000378:metabolism / Q000382:microbiology; D007408:Intestinal Absorption; D007410:Intestinal Diseases / Q000150:complications / Q000378:metabolism* / Q000382:microbiology; D007422:Intestines / Q000382:microbiology; D000090463:Iron Deficiencies; D019266:Iron, Dietary / Q000493:pharmacokinetics*; D008286:Malabsorption Syndromes / Q000150:complications; D008322:Mammals / Q000378:metabolism; D064307:Microbiota; D012148:Restless Legs Syndrome / Q000209:etiology; D000098742:Ferroportin
chemical_list: D027682:Cation Transport Proteins; D019266:Iron, Dietary; D000098742:Ferroportin
keywords: Anémie ferriprive; Carence en fer; Fatigue; Iron deficiency; Iron deficiency anemia; Metabolism; Microbiota; Microbiote; Métabolisme