title: Colorectal liver metastases guidelines, tumor heterogeneity and clonal evolution: can this be translated to patient benefit?
authors.affiliation: Centre for Biosystems & Genomic Network Medicine, CBS.GenNetMed, University of Ioannina, Ioannina, GR 451 10, Greece.
authors.forename: Georgios D
authors.initials: GD
authors.lastname: Lianos
authors.forename: Georgios K
authors.initials: GK
authors.lastname: Glantzounis
authors.forename: Alberto
authors.initials: A
authors.lastname: Mangano
authors.forename: Stefano
authors.initials: S
authors.lastname: Rausei
authors.forename: Dimitrios H
authors.initials: DH
authors.lastname: Roukos
mesh_terms: D060965:Clonal Evolution; D015179:Colorectal Neoplasms / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000473:pathology* / Q000556:secondary* / Q000601:surgery; D017410:Practice Guidelines as Topic; D011379:Prognosis
keywords: colorectal cancer; colorectal liver metastases; genetic variants; intratumor heterogeneity; next-generation sequencing analyses