title: Neuropsychiatric complications in a patient with Marfan syndrome.
abstract: BACKGROUND
  Marfan syndrome (MFS) is an autosomal dominant disorder of fibrillin-1 gene mutations, with the involvement of cardiovascular, skeletal, and ocular systems. In addition to physical abnormalities, MFS patients are also found to be susceptible to schizophrenia and other psychiatric conditions.
  
  
  OBJECTIVE
  Awareness of the association between MFS and psychiatric conditions would improve the clinical management of MFS patients to reduce the risk or even to prevent the development of psychiatric complications in MFS patients.
  
  
  METHODS
  Here, we describe a male MFS patient who manifested incoherent speech and impaired cognitive and social function at the age of 40 years. Results and conclusion His mental dysfunction could be attributed to his bilateral cerebral infarction, which is a neurovascular complication associated with MFS.
authors.affiliation: 1 Department of Psychiatry, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: Chin-Pang
authors.initials: CP
authors.lastname: Lee
authors.affiliation: 1 Department of Psychiatry, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: Chun-Lin
authors.initials: CL
authors.lastname: Chu
authors.affiliation: 1 Department of Psychiatry, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: Chia-Yih
authors.initials: CY
authors.lastname: Liu
authors.affiliation: 1 Department of Psychiatry, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: Chia-Hsiang
authors.initials: CH
authors.lastname: Chen