title: Comparison of surgical stress responses during spinal and general anesthesia in curettage surgery.
abstract: BACKGROUND
  Response to the surgical stress is an involuntary response to metabolic, autonomic as well as hormonal changes that leads to heart rate and blood pressure fluctuations.
  
  
  OBJECTIVE
  This study aimed to investigate the effect of general versus spinal anesthesia on blood sugar level and hemodynamic changes in patients undergoing curettage surgery.
  
  
  METHODS
  In this randomized clinical trial, 50 patients who were candidate for elective curettage surgery were divided into two groups of general (n = 25) and spinal (n = 25) anesthesia. In both groups, blood glucose level was evaluated 10 minutes before, 20 and 60 minutes after initiation of anesthesia. Also, heart rate and mean arterial blood pressure were evaluated at 10 minutes before, 10, 20, 30, 40, 50 and 60 minutes after intiation of anesthesia.
  
  
  RESULTS
  There was not significantly difference between blood glucose level of both groups during 10 minutes before, 20 and 60 minutes after the intiation of anesthesia. Heart rate changes in the general and spinal groups compared to the baseline level were decreased up to maximum12.5% and 14.5%, respectively. The mean arterial pressure changes in the general and spinal groups compared to the baseline level were decreased up to maximum 5.4% and 8%, respectively.
  
  
  CONCLUSIONS
  Blood glucose and hemodynamic changes caused by surgical stress were not significantly different between two groups.
authors.affiliation: Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran ; Department of Anesthesiology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Fereshteh
authors.initials: F
authors.lastname: Amiri
authors.affiliation: Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran ; Department of Anesthesiology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Ghomeishi
authors.affiliation: Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran ; Department of Anesthesiology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Seyed Mohammad Mehdi
authors.initials: SM
authors.lastname: Aslani
authors.affiliation: Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran ; Department of Anesthesiology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Sholeh
authors.initials: S
authors.lastname: Nesioonpour
authors.affiliation: Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran ; Student Research Committee, Nursing and Midwifery School, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Sara
authors.initials: S
authors.lastname: Adarvishi
keywords: Anesthesia; Blood glucose; Curettage; Spinal