title: Direct regioselective phosphonation of heteroaryl N-oxides with H-phosphonates under metal and external oxidant free conditions.
abstract: A direct C-H/P-H functionalization of heteroaryl N-oxides with H-phosphonates is described. A wide variety of heteroaryl phosphonates were obtained in up to 92% yield in a chemo- and regioselective manner, under oxidant and metal free conditions. This procedure features practicality, high efficiency, environmental friendliness and atom economy.
authors.affiliation: Department of Chemistry, Henan Key Laboratory of Chemical Biology and Organic Chemistry, Key Laboratory of Applied Chemistry of Henan Universities, Zhengzhou University, Zhengzhou, 450052, P. R. China. cuixl@zzu.edu.cn.
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Xiuling
authors.initials: X
authors.lastname: Cui
authors.forename: Yu
authors.initials: Y
authors.lastname: Pei
authors.forename: Qianqian
authors.initials: Q
authors.lastname: Zhang
authors.forename: Jie
authors.initials: J
authors.lastname: Bai
authors.forename: Donghui
authors.initials: D
authors.lastname: Wei
authors.forename: Yangjie
authors.initials: Y
authors.lastname: Wu
mesh_terms: D008670:Metals; D063065:Organophosphonates / Q000737:chemistry*; D016877:Oxidants; D010087:Oxides / Q000737:chemistry*; D014992:Xylenes / Q000737:chemistry
chemical_list: D008670:Metals; D063065:Organophosphonates; D016877:Oxidants; D010087:Oxides; D014992:Xylenes