title: First report of NDM-1-producing Acinetobacter baumannii sequence type 25 in Brazil.
abstract: New Delhi metallo-β-lactamase 1 (NDM-1) was first identified in Brazil in Enterobacter hormaechei and Providencia rettgeri in 2013. Here, we describe the first case of NDM-1-producing Acinetobacter baumannii sequence type 25 isolated from the urinary tract of a 71-year-old man who died of multiple complications, including A. baumannii infection. The NDM-1 gene was detected by quantitative PCR, and its sequence confirmed its presence in an ∼ 100-kb plasmid.
authors.affiliation: Pontifical Catholic University, School of Health and Biosciences, Curitiba, PR, Brazil State Central Public Health Laboratory, São José dos Pinhais, PR, Brazil marcelopilonetto@gmail.com.
authors.forename: Marcelo
authors.initials: M
authors.lastname: Pillonetto
authors.affiliation: State Central Public Health Laboratory, São José dos Pinhais, PR, Brazil.
authors.forename: Lavinia
authors.initials: L
authors.lastname: Arend
authors.affiliation: University Hospital of Londrina, Londrina, PR, Brazil.
authors.forename: Eliana Carolina
authors.initials: EC
authors.lastname: Vespero
authors.affiliation: University Hospital of Londrina, Londrina, PR, Brazil.
authors.forename: Marsileni
authors.initials: M
authors.lastname: Pelisson
authors.affiliation: Laboratório de Pesquisa em Infecção Hospitalar (LAPIH), Instituto Oswaldo Cruz-FIOCRUZ, Rio de Janeiro, RJ, Brazil.
authors.forename: Thiago Pavoni Gomes
authors.initials: TP
authors.lastname: Chagas
authors.affiliation: Laboratório de Pesquisa em Infecção Hospitalar (LAPIH), Instituto Oswaldo Cruz-FIOCRUZ, Rio de Janeiro, RJ, Brazil.
authors.forename: Ana Paula D'Alincourt
authors.initials: AP
authors.lastname: Carvalho-Assef
authors.affiliation: Laboratório de Pesquisa em Infecção Hospitalar (LAPIH), Instituto Oswaldo Cruz-FIOCRUZ, Rio de Janeiro, RJ, Brazil.
authors.forename: Marise Dutra
authors.initials: MD
authors.lastname: Asensi
mesh_terms: D000151:Acinetobacter Infections / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D040981:Acinetobacter baumannii / Q000187:drug effects / Q000201:enzymology / Q000235:genetics* / Q000302:isolation & purification; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D015373:Bacterial Typing Techniques; D001938:Brazil; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000737:chemistry* / Q000378:metabolism; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D018440:beta-Lactam Resistance / Q000235:genetics*; D001618:beta-Lactamases / Q000235:genetics* / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases; C552864:beta-lactamase NDM-1