title: [Modern methods of correction of systemic inflammation and insulin resistance by patients with coronary heart disease and diabetes mellitus type 2].
abstract: Mediterranean diet and regular exercise are the best means to reduce the systemic smoldering inflammation (SI) and insulin resistance (IR). Of drugs prescribed to patients with diabetes mellitus type 2, have the greatest effect receptor agonists that activate the peroxisome proliferator (PPAR], activators of incretine and metformin. Debate the use of "submaximal" double and triple agonist PPAR. Sulfonylurea drugs have very weak anti-inflammatory effect and is not reduce insulin resistance, and insulin as monotherapy increases IR.
authors.forename: M S
authors.initials: MS
authors.lastname: Rasin
authors.forename: Z A
authors.initials: ZA
authors.lastname: Shaenko
mesh_terms: D003327:Coronary Disease / Q000150:complications / Q000378:metabolism / Q000628:therapy*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000378:metabolism / Q000628:therapy*; D038441:Diet, Mediterranean; D015444:Exercise; D058607:Fibric Acids / Q000627:therapeutic use; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007249:Inflammation / Q000150:complications / Q000378:metabolism / Q000628:therapy; D007328:Insulin / Q000627:therapeutic use; D007333:Insulin Resistance; D008687:Metformin / Q000627:therapeutic use; D000077205:Pioglitazone; D013453:Sulfonylurea Compounds / Q000627:therapeutic use; D013844:Thiazoles / Q000627:therapeutic use; D045162:Thiazolidinediones / Q000627:therapeutic use
chemical_list: D058607:Fibric Acids; C425931:GW 501516; D007004:Hypoglycemic Agents; D007328:Insulin; D013453:Sulfonylurea Compounds; D013844:Thiazoles; D045162:Thiazolidinediones; D008687:Metformin; D000077205:Pioglitazone