title: Apixaban exerts anti-inflammatory effects in mesangial cells by blocking thrombin/protease-activated receptor-1 system.
authors.affiliation: Department of Pathophysiology and Therapeutics of Diabetic Vascular Complications, Kurume University School of Medicine, Kurume, Japan.
authors.forename: Yuji
authors.initials: Y
authors.lastname: Ishibashi
authors.affiliation: Department of Pathophysiology and Therapeutics of Diabetic Vascular Complications, Kurume University School of Medicine, Kurume, Japan.
authors.forename: Takanori
authors.initials: T
authors.lastname: Matsui
authors.affiliation: Department of Pathophysiology and Therapeutics of Diabetic Vascular Complications, Kurume University School of Medicine, Kurume, Japan. Electronic address: shoichi@med.kurume-u.ac.jp.
authors.forename: Sho-ichi
authors.initials: S
authors.lastname: Yamagishi
mesh_terms: D000893:Anti-Inflammatory Agents / Q000493:pharmacokinetics*; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D065427:Factor Xa Inhibitors / Q000494:pharmacology; D006801:Humans; D050527:Mesangial Cells / Q000187:drug effects* / Q000276:immunology*; D011720:Pyrazoles / Q000494:pharmacology*; D011728:Pyridones / Q000494:pharmacology*; D044463:Receptor, PAR-1 / Q000276:immunology*; D013917:Thrombin / Q000037:antagonists & inhibitors* / Q000276:immunology*
chemical_list: D000893:Anti-Inflammatory Agents; D065427:Factor Xa Inhibitors; D011720:Pyrazoles; D011728:Pyridones; D044463:Receptor, PAR-1; C522181:apixaban; D013917:Thrombin