title: Noninvasive brain-computer interface enables communication after brainstem stroke.
abstract: Brain-computer interfaces (BCIs) provide communication that is independent of muscle control, and can be especially important for individuals with severe neuromuscular disease who cannot use standard communication pathways or other assistive technology. It has previously been shown that people with amyotrophic lateral sclerosis (ALS) can successfully use BCI after all other means of independent communication have failed. The BCI literature has asserted that brainstem stroke survivors can also benefit from BCI use. This study used a P300-based event-related potential spelling system. This case study demonstrates that an individual locked-in owing to brainstem stroke was able to use a noninvasive BCI to communicate volitional messages. Over a period of 13 months, the participant was able to successfully operate the system during 40 of 62 recording sessions. He was able to accurately spell words provided by the experimenter and to initiate dialogues with his family. The results broadly suggest that, regardless of the precipitating event, BCI use may be of benefit to those with locked-in syndrome.
authors.affiliation: Department of Psychology, East Tennessee State University, Johnson City, TN 37614, USA. sellers@etsu.edu.
authors.forename: Eric W
authors.initials: EW
authors.lastname: Sellers
authors.affiliation: Department of Psychology, East Tennessee State University, Johnson City, TN 37614, USA.
authors.forename: David B
authors.initials: DB
authors.lastname: Ryan
authors.affiliation: Department of Psychology, East Tennessee State University, Johnson City, TN 37614, USA. Department of Neurobiology and Anatomy, Wake Forest University, Winston Salem, NC 27106, USA.
authors.forename: Christopher K
authors.initials: CK
authors.lastname: Hauser
mesh_terms: D000465:Algorithms; D020526:Brain Stem Infarctions / Q000534:rehabilitation*; D062207:Brain-Computer Interfaces; D003143:Communication Devices for People with Disabilities; D038524:Diffusion Magnetic Resonance Imaging; D004569:Electroencephalography; D018913:Event-Related Potentials, P300; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D011782:Quadriplegia / Q000534:rehabilitation*; D013647:Task Performance and Analysis; D057170:Translational Research, Biomedical