title: Statins, glycemia, and diabetes mellitus: another point of view.
abstract: Glycemic effects of statins have recently become a topic of heated debate. On closer inspection, however, the prevailing opinion regarding this issue may prove to be unsubstantiated. We suggest that the harmful effect of statin-induced diabetes is likely overestimated, and the consequences of the glycemic effects of statins may, theoretically, apply to a greater number of patients beyond just those with statin-induced diabetes. Most notably, though, careful consideration of the issue suggests, albeit surprisingly, that the clinical implications of the glycemic effects of statins may actually be rather limited.
authors.affiliation: 3rd Department of Internal Medicine, 1st Faculty of Medicine, Charles University, U Nemocnice 1, Praha 2 / Prague, CZ 128 21, Czech Republic, TSTULC@LF1.CUNI.CZ.
authors.forename: Tomáš
authors.initials: T
authors.lastname: Stulc
authors.forename: Richard
authors.initials: R
authors.lastname: Ceška
mesh_terms: D001786:Blood Glucose / Q000187:drug effects*; D002318:Cardiovascular Diseases / Q000503:physiopathology* / Q000517:prevention & control; D003920:Diabetes Mellitus / Q000139:chemically induced* / Q000503:physiopathology; D005260:Female; D038321:Glycemic Index; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D006937:Hypercholesterolemia / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D020380:Needs Assessment; D018570:Risk Assessment; D012680:Sensitivity and Specificity
chemical_list: D001786:Blood Glucose; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors