title: Improved repair of bone defects with prevascularized tissue-engineered bones constructed in a perfusion bioreactor.
abstract: Vascularization of tissue-engineered bones is critical to achieving satisfactory repair of bone defects. The authors investigated the use of prevascularized tissue-engineered bone for repairing bone defects. The new bone was greater in the prevascularized group than in the non-vascularized group, indicating that prevascularized tissue-engineered bone improves the repair of bone defects. [Orthopedics. 2014; 37(10):685-690.].
authors.forename: De-Qiang
authors.initials: DQ
authors.lastname: Li
authors.forename: Ming
authors.initials: M
authors.lastname: Li
authors.forename: Pei-Lai
authors.initials: PL
authors.lastname: Liu
authors.forename: Yuan-Kai
authors.initials: YK
authors.lastname: Zhang
authors.forename: Jian-Xi
authors.initials: JX
authors.lastname: Lu
authors.forename: Jian-Min
authors.initials: JM
authors.lastname: Li
mesh_terms: D000818:Animals; D019149:Bioreactors; D001854:Bone Marrow Cells; D001861:Bone Regeneration; D016025:Bone Transplantation; D001842:Bone and Bones / Q000098:blood supply / Q000601:surgery*; D018920:Coculture Techniques; D042783:Endothelial Cells; D005269:Femur / Q000293:injuries / Q000601:surgery*; D059630:Mesenchymal Stem Cells; D023421:Models, Animal; D010006:Osteoblasts; D012756:Sheep; D023822:Tissue Engineering; D054457:Tissue Scaffolds