title: Epigenetic mechanisms of perinatal programming: translational approaches from rodent to human and back.
abstract: Perinatal life is a period of enhanced plasticity and susceptibility to environmental effects via the maternal environment or parental care. A variety of studies have indicated that epigenetic mechanisms, which can alter gene function without a change in gene sequence, play a role in setting developmental trajectories that impact health, including mental health. This chapter reviews examples of translational approaches to the study of biological embedding of mental health via differences in parental care.
authors.affiliation: Department of Biological Sciences, Centre for Environmental Epigenetics and Development, University of Toronto, Scarborough, Toronto, ON, Canada, pmcgowan@utsc.utoronto.ca.
authors.forename: Patrick O
authors.initials: PO
authors.lastname: McGowan