title: Tritiation and characterization of several suicide substrate enzyme inactivators.
abstract: Methods are presented to tritiate the enzyme inhibitors pargyline and caracemide.
authors.affiliation: PerkinElmer Life Sciences & Technology, Inc., 940 Winter Street, Waltham, MA 02451, United States.
authors.forename: Judith A
authors.initials: JA
authors.lastname: Egan
authors.affiliation: PerkinElmer Life Sciences & Technology, Inc., 940 Winter Street, Waltham, MA 02451, United States. Electronic address: crist.filer@perkinelmer.com.
authors.forename: Crist N
authors.initials: CN
authors.lastname: Filer
mesh_terms: D004791:Enzyme Inhibitors / Q000032:analysis / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D006918:Hydroxyurea / Q000031:analogs & derivatives* / Q000737:chemistry; D007553:Isotope Labeling / Q000379:methods*; D008422:Materials Testing; D010293:Pargyline / Q000737:chemistry*; D019275:Radiopharmaceuticals / Q000032:analysis / Q000138:chemical synthesis; D014316:Tritium / Q000032:analysis / Q000737:chemistry*
chemical_list: D004791:Enzyme Inhibitors; D019275:Radiopharmaceuticals; D014316:Tritium; D006859:Hydrogen; D010293:Pargyline; C044466:caracemide; D006918:Hydroxyurea
keywords: Caracemide; Enzyme inactivation; Pargyline; Tritium; Tritium NMR