title: Controlling influenza epidemics.
abstract: Vaccination in most countries against influenza virus epidemics is by administration of either inactivated (non-infectious) whole virus preparations or a preparation which contains isolated viral antigens. There is considerable evidence to indicate that natural infection of humans by influenza virus confers more complete and long-lasting protection against subsequent outbreaks than does vaccination with inactivated whole virus and, presumably, subunit vaccines. This article summarizes recent evidence supporting these epidemiological observations.
authors.affiliation: Department of Microbiology, John Curtin School of Medical Research, Australian National University, Canberra, A.C.T. 2601, Australia.
authors.forename: G L
authors.initials: GL
authors.lastname: Ada