title: [The auditory pathway: levels of integration of information and principal neurotransmitters].
abstract: In this paper we studied the central auditory pathway (CAP) from an anatomical, physiological and neurochemical standpoint, from the inner ear, brainstem, thalamus to the temporal auditory cortex. The characteristics of the spiral ganglion of Corti, auditory nerve, cochlear nuclei, superior olivary complex, lateral lemniscus, inferior colliculus, medial geniculate body, and auditory cortex, including the auditory efferent pathway, are given. CAP is described as the electrical impulses, travelling through axons, allowing ions to enter a neuron and vesicles with neurotransmitters (NT) and then released into synaptic space. The NT changes the functioning of the cells; when attached to specific receptors on the next nerve cell, NT-receiver union causes input of ions through Gap sites, resulting in a postsynaptic potential that is spread over all CAP. In addition, the effects of the NT are not limited to the transmission, but as trophic agents that promote the formation of new neural networks. Even the anatomy, physiology, neurochemical aspects, and the different types of synapses are not fully understood to comprehend the organization of the CAP, but remain under investigation because of the relevance for the treatment of various central auditory disorders.
authors.affiliation: Servicio de Genética, Instituto Nacional de Rehabilitación, México, D.F.
authors.forename: Edgar
authors.initials: E
authors.lastname: Hernández-Zamora
authors.affiliation: Laboratorio de Neurofisiología Cognoscitiva, Instituto Nacional de Rehabilitación, México, D.F.
authors.forename: Adrián
authors.initials: A
authors.lastname: Poblano
mesh_terms: D001303:Auditory Cortex / Q000378:metabolism; D001306:Auditory Pathways / Q000502:physiology*; D006801:Humans; D018377:Neurotransmitter Agents / Q000378:metabolism*; D013569:Synapses / Q000378:metabolism*; D009435:Synaptic Transmission / Q000502:physiology
chemical_list: D018377:Neurotransmitter Agents