title: Three new carbazole alkaloids and biological activities of Murraya koenigii.
abstract: Three new carbazole alkaloids, mukoenigatin (1), bikoeniquinonine (2) and murrayadinal (3), were isolated from the aerial parts of Murraya koenigii, along with mukeonine-B (4). Their molecular structures were determined on the basis of spectral analysis including UV, IR, MS, and 2D NMR spectroscopy. The antimicrobial activity of different fractions of plant extract was also determined.
authors.affiliation: a Department of Chemistry , University of Karachi , Karachi 75270 , Pakistan.
authors.forename: Shaista
authors.initials: S
authors.lastname: Naz
authors.forename: Sumayya
authors.initials: S
authors.lastname: Saied
authors.forename: Afifa
authors.initials: A
authors.lastname: Ahmed
authors.forename: Syed Muhammad
authors.initials: SM
authors.lastname: Shahid
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002227:Carbazoles / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002939:Ciprofloxacin / Q000494:pharmacology; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D032101:Murraya / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D010154:Pakistan; D018515:Plant Leaves / Q000737:chemistry; D014640:Vancomycin / Q000494:pharmacology
chemical_list: D000470:Alkaloids; D000900:Anti-Bacterial Agents; D002227:Carbazoles; C000596396:bikoeniquinonine; C000596395:mukoenigatin; C000596397:murrayadinal; D002939:Ciprofloxacin; D014640:Vancomycin
keywords: Murraya koenigii; Rutaceae; bikoeniquinonine; carbazole alkaloids; mukoenigatin; murrayadinal