title: Reinventing the neural crest: direct reprogramming makes iNCCs.
abstract: Aberrant neural crest (NC) development is at the origin of many congenital diseases. Given the limitations in human NC cell isolation and expansion, the development of new strategies for NC generation is crucial. In this issue of Cell Stem Cell, Kim et al. (2014) report the direct reprogramming of postnatal fibroblasts into multipotent NC cells.
authors.affiliation: Institute of Anatomy, University of Zurich, 8057 Zurich, Switzerland.
authors.forename: Sandra
authors.initials: S
authors.lastname: Varum
authors.affiliation: Institute of Anatomy, University of Zurich, 8057 Zurich, Switzerland. Electronic address: lukas.sommer@anatom.uzh.ch.
authors.forename: Lukas
authors.initials: L
authors.lastname: Sommer
mesh_terms: D000818:Animals; D065150:Cellular Reprogramming; D006801:Humans; D039902:Multipotent Stem Cells / Q000166:cytology*; D009432:Neural Crest / Q000166:cytology*; D055757:SOXE Transcription Factors / Q000378:metabolism*
chemical_list: D055757:SOXE Transcription Factors