title: Guidelines for treatment of severe sepsis/septic shock: tissue perfusion assessment.
abstract: Sepsis is a very frequent condition and causes high mortality rates and healthcare costs; it is the main cause of death in intensive care units. Clear, improved prognosis was shown for early diagnosed and treated patients. Treatment guidelines are fundamental for appropriate therapy. It is clear that hypoperfusion patients should be hemodynamically optimized; therefore, recognition of hypoperfusion signs is one of the main therapeutic steps. This guideline discusses the current literature and available data regarding the evaluation of hemodynamic parameters.
authors.affiliation: Associação de Medicina Intensiva Brasileira, Brasil.
authors.forename: Glauco Adrieno
authors.initials: GA
authors.lastname: Westphal
authors.affiliation: Associação de Medicina Intensiva Brasileira, Brasil.
authors.forename: Anderson R
authors.initials: AR
authors.lastname: Gonçalves
authors.affiliation: Associação de Medicina Intensiva Brasileira, Brasil.
authors.forename: Milton
authors.initials: M
authors.lastname: Caldeira Filho
authors.affiliation: Associação de Medicina Intensiva Brasileira, Brasil.
authors.forename: Eliezer
authors.initials: E
authors.lastname: Silva
authors.affiliation: Instituto Latino Americano de Sepse, Brasil.
authors.forename: Reinaldo
authors.initials: R
authors.lastname: Salomão
authors.affiliation: Sociedade Brasileira de Infectologia, Brasil.
authors.forename: Wanderley Marques
authors.initials: WM
authors.lastname: Bernardo
authors.affiliation: Associação de Medicina Intensiva Brasileira, Brasil.
authors.forename: Flávia Ribeiro
authors.initials: FR
authors.lastname: Machado