title: Ubiquitination of pattern recognition receptors in plant  innate immunity.
abstract: Lacking an adaptive immune system, plants largely rely on plasma membrane-resident pattern recognition receptors (PRRs) to sense pathogen invasion. The activation of PRRs leads to the profound immune responses that coordinately contribute to the restriction of pathogen multiplication. Protein post-translational modifications dynamically shape the intensity and duration of the signalling pathways. In this review, we discuss the specific regulation of PRR activation and signalling by protein ubiquitination, endocytosis and degradation, with a particular focus on the bacterial flagellin receptor FLS2 (flagellin sensing 2) in Arabidopsis.
authors.affiliation: Department of Plant Pathology and Microbiology, and Institute for Plant Genomics and Biotechnology, Texas A&M University, College Station, TX 77843, USA.|The Provincial Key Lab of Plant Pathology of Hubei Province, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Li
authors.affiliation: Center for Agricultural Resources Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Shijiazhuang, Hebei 050021, China.
authors.forename: Dongping
authors.initials: D
authors.lastname: Lu
authors.affiliation: Department of Plant Pathology and Microbiology, and Institute for Plant Genomics and Biotechnology, Texas A&M University, College Station, TX 77843, USA.
authors.forename: Libo
authors.initials: L
authors.lastname: Shan
mesh_terms: D007113:Immunity, Innate; D010944:Plants / Q000276:immunology*; D011956:Receptors, Cell Surface / Q000378:metabolism*; D015398:Signal Transduction; D054875:Ubiquitination
chemical_list: D011956:Receptors, Cell Surface