title: Health and economic burden of obesity in elderly individuals with asthma in the United States.
abstract: The health and economic burden of obesity among elderly individuals with asthma has not been adequately studied. This study assessed the association between obesity and asthma among the elderly and examined the impact of obesity on asthma-related and total health care costs among elderly individuals with asthma. This was a retrospective analysis of the 2006-2010 Medical Expenditure Panel Survey (MEPS) data. Individuals aged 65 years or older were included in the study. Individuals with asthma were identified by an International Classification of Diseases, Ninth Revision code of 493 or a Clinical Classification Code of 128. Individuals with a self-reported body mass index ≥ 30 kg/m(2) were considered to be obese. Logistic regression was used to assess the relationship between obesity and asthma. Generalized linear models with gamma distribution and log link were used to assess the relationship between obesity and asthma-related and total direct medical costs. All analyses were conducted while accounting for the complex survey design of MEPS. In all, 675 elderly individuals were identified as having asthma, 292 of whom were obese. Obese elderly individuals were more likely to suffer from asthma as compared to the nonobese (odds ratio, 1.71; 95% confidence interval [CI],1.37-2.12). Obesity was a significant predictor of asthma-related costs (β: 0.537; 95% CI: 0.18-0.89; P= 0.003) and total health care costs (β: 0.154; 95% CI: 0.08-0.23; P = 0.001) among elderly individuals with asthma after controlling for sociodemographics and comorbidities. Appropriate weight management measures should be recommended to obese elderly individuals with asthma to improve asthma control and reduce health care costs.
authors.affiliation: Department of Pharmacy Administration, The University of Mississippi School of Pharmacy, University, Mississippi.
authors.forename: Ruchit
authors.initials: R
authors.lastname: Shah
authors.affiliation: Department of Pharmacy Administration, The University of Mississippi School of Pharmacy, University, Mississippi.
authors.forename: Yi
authors.initials: Y
authors.lastname: Yang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001249:Asthma / Q000453:epidemiology* / Q000517:prevention & control; D015897:Comorbidity; D017281:Cost of Illness; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D017048:Health Care Costs; D006801:Humans; D006949:Hyperlipidemias / Q000453:epidemiology; D006973:Hypertension / Q000453:epidemiology; D016015:Logistic Models; D008297:Male; D009765:Obesity / Q000191:economics* / Q000453:epidemiology*; D014481:United States / Q000453:epidemiology; D061217:Weight Reduction Programs