title: [Low-grade adenocarcinoma of nasal cavities: a case report].
abstract: Low-grade sinonasal adenocarcinomas are uncommon and recently described entities. Its histologic diagnosis is challenging. This tumour is characterized by a tendency to local invasion, and rare distant metastases. Well treated, the prognosis is excellent. We describe a case of low-grade nasal cavity adenocarcinoma and discuss the anatomoclinical, therapeutic and evolutionary characteristics of this malignant tumour. A 54-year-old female patient presented with a 10 years history of right-sided nasal obstruction and recurrent epistaxis. On examination the patient had a large, firm mass in the right nasal cavity. Endoscopic sinonasal surgery was performed. The lesion was found to originate from the posteriolateral wall of the right nasal cavity. Histopathology analysis identified a low-grade sinonasal adenocarcinoma. Upon follow-up 4 years after surgery, the patient exhibited no clinical evidence of recurrence. Low-grade sinonasal adenocarcinomas are poorly defined neoplasms, accounting for 4 to 20% of all sinonasal malignancies. The nasal cavity is the most frequently involved site. Low-grade sinonasal adenocarcinomas pose a diagnostic challenge for the pathologist because they must be distinguished from benign tumours, especially adenomas. The primary treatment of sinonasal adenocarcinoma is complete surgical excision.
authors.affiliation: Service d'ORL et chirurgie cervicofaciale, CHU Habib-Bourguiba, 3029 Sfax, Tunisie. Electronic address: imenachour2@gmail.com.
authors.forename: I
authors.initials: I
authors.lastname: Achour
authors.affiliation: Service d'ORL et chirurgie cervicofaciale, CHU Habib-Bourguiba, 3029 Sfax, Tunisie.
authors.forename: A
authors.initials: A
authors.lastname: Chakroun
authors.affiliation: Service de carcinologie radiothérapie, CHU Habib-Bourguiba, 3029 Sfax, Tunisie.
authors.forename: J
authors.initials: J
authors.lastname: Daoud
authors.affiliation: Service d'ORL et chirurgie cervicofaciale, CHU Habib-Bourguiba, 3029 Sfax, Tunisie.
authors.forename: B
authors.initials: B
authors.lastname: Hammami
authors.affiliation: Service d'ORL et chirurgie cervicofaciale, CHU Habib-Bourguiba, 3029 Sfax, Tunisie.
authors.forename: A
authors.initials: A
authors.lastname: Ghorbel
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D004844:Epistaxis / Q000209:etiology; D005260:Female; D006801:Humans; D008444:Maxillary Sinus Neoplasms / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D015508:Nasal Obstruction / Q000209:etiology; D009669:Nose Neoplasms / Q000473:pathology* / Q000601:surgery
keywords: Adenocarcinoma; Adénocarcinome; Chirurgie; Fosse nasale; Immuno-histochimie; Immunohistopathology; Nasal cavity; Radiotherapy; Radiothérapie; Surgery