title: Decarboxylative acylation of indolines with α-keto acids under palladium catalysis: a facile strategy for the synthesis of 7-substituted indoles.
abstract: Palladium-catalyzed decarboxylative acylation of highly substituted indolines with α-keto acids via C-H bond activation is described. This protocol provides efficient access to C7-carbonylated indoles known to have diverse biological profiles.
authors.affiliation: School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea. insukim@skku.edu.
authors.forename: Minyoung
authors.initials: M
authors.lastname: Kim
authors.forename: Neeraj Kumar
authors.initials: NK
authors.lastname: Mishra
authors.forename: Jihye
authors.initials: J
authors.lastname: Park
authors.forename: Sangil
authors.initials: S
authors.lastname: Han
authors.forename: Youngmi
authors.initials: Y
authors.lastname: Shin
authors.forename: Satyasheel
authors.initials: S
authors.lastname: Sharma
authors.forename: Youngil
authors.initials: Y
authors.lastname: Lee
authors.forename: Eui-Kyung
authors.initials: EK
authors.lastname: Lee
authors.forename: Jong Hwan
authors.initials: JH
authors.lastname: Kwak
authors.forename: In Su
authors.initials: IS
authors.lastname: Kim
mesh_terms: D000215:Acylation; D002384:Catalysis; D003653:Decarboxylation; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D007651:Keto Acids / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: D007211:Indoles; D007651:Keto Acids; D010165:Palladium; C057812:indoline