title: Intra-vaginal prostaglandin E2 versus double-balloon catheter for labor induction in term oligohydramnios.
abstract: OBJECTIVE
  Compare mechanical and pharmacological ripening for patients with oligohydramnios at term.
  
  
  METHODS
  Fifty-two patients with oligohydramnios ⩽ 5 cm and Bishop score ⩽ 6 were randomized for labor induction with a vaginal insert containing 10 mg timed-release dinoprostone (PGE2) or double-balloon catheter. The primary outcome was time from induction to active labor. Time to labor, neonatal outcomes and maternal satisfaction were also compared.
  
  
  RESULTS
  Baseline characteristics were similar. Time from induction to active labor (13 with PGE2 vs 19.5 h with double-balloon catheter; P = 0.243) was comparable, with no differences in cesarean rates (15.4 vs 7.7%; P = 0.668) or neonatal outcomes. The PGE2 group had higher incidence of early device removal (76.9 vs 26.9%; P = 0.0001), mostly because of active labor or non-reassuring fetal heart rate. Fewer PGE2 patients required oxytocin augmentation for labor induction (53.8 vs 84.6% P = 0.034). Time to delivery was significantly shorter with PGE2 (16 vs 20.5 h; P = 0. 045).
  
  
  CONCLUSIONS
  Intravaginal PGE2 and double-balloon catheter are comparable methods for cervical ripening in term pregnancies with oligohydramnios.
authors.affiliation: Department of OBGYN, Meir Medical Center, Kfar Saba, Israel.
authors.forename: G
authors.initials: G
authors.lastname: Shechter-Maor
authors.affiliation: Department of OBGYN, Meir Medical Center, Kfar Saba, Israel.
authors.forename: G
authors.initials: G
authors.lastname: Haran
authors.affiliation: Department of OBGYN, Meir Medical Center, Kfar Saba, Israel.
authors.forename: D
authors.initials: D
authors.lastname: Sadeh-Mestechkin
authors.affiliation: Department of OBGYN, Meir Medical Center, Kfar Saba, Israel.
authors.forename: Y
authors.initials: Y
authors.lastname: Ganor-Paz
authors.affiliation: 1] Department of OBGYN, Meir Medical Center, Kfar Saba, Israel [2] Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: M D
authors.initials: MD
authors.lastname: Fejgin
authors.affiliation: 1] Department of OBGYN, Meir Medical Center, Kfar Saba, Israel [2] Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: T
authors.initials: T
authors.lastname: Biron-Shental
mesh_terms: D000282:Administration, Intravaginal; D000328:Adult; D002408:Catheters, Indwelling; D020070:Cervical Ripening / Q000187:drug effects*; D015232:Dinoprostone / Q000008:administration & dosage*; D005260:Female; D005323:Fetal Monitoring / Q000379:methods; D006801:Humans; D007751:Labor, Induced / Q000295:instrumentation / Q000379:methods; D016104:Oligohydramnios / Q000175:diagnosis*; D010120:Oxytocics / Q000008:administration & dosage; D017060:Patient Satisfaction; D011247:Pregnancy; D011256:Pregnancy Outcome; D047929:Term Birth / Q000187:drug effects; D016896:Treatment Outcome
chemical_list: D010120:Oxytocics; D015232:Dinoprostone