title: [Immune activation and inflammation in chronic heart failure].
abstract: This survey shows that among chronic heart failure (CHF) and its characteristic inflammation observed mutual activation. Given the role of inflammation in the pathophysiology of heart failure, it is to study how the combination drug treatment of CHF, its variants influence on markers of inflammation. It is expedient to determine not only the level of cytokines, but also acute phase proteins (haptoglobin, seroglikoidy C3-complement, transferrin), reflecting inflammation and necrosis in the connective tissue, as well as IgA, IgG, IgM and protein spectrum. The importance of the study of haptoglobin due to its involvement in the metabolism of hemoglobin and transferrin--the exchange of iron.
authors.forename: V K
authors.initials: VK
authors.lastname: Kazimirko
authors.forename: V V
authors.initials: VV
authors.lastname: Kutovoĭ
authors.forename: L N
authors.initials: LN
authors.lastname: Ivanitskaia
authors.forename: A G
authors.initials: AG
authors.lastname: Dubkova
authors.forename: T S
authors.initials: TS
authors.lastname: Silant'eva
mesh_terms: D000209:Acute-Phase Proteins / Q000378:metabolism; D015415:Biomarkers / Q000097:blood; D002908:Chronic Disease; D003176:Complement C3 / Q000378:metabolism; D016207:Cytokines / Q000097:blood; D006242:Haptoglobins / Q000378:metabolism; D006333:Heart Failure / Q000097:blood / Q000150:complications / Q000276:immunology* / Q000473:pathology; D006801:Humans; D007107:Immune System / Q000378:metabolism* / Q000473:pathology; D007249:Inflammation / Q000097:blood / Q000150:complications / Q000276:immunology / Q000473:pathology; D014168:Transferrin / Q000378:metabolism
chemical_list: D000209:Acute-Phase Proteins; D015415:Biomarkers; D003176:Complement C3; D016207:Cytokines; C485359:HP protein, human; D006242:Haptoglobins; D014168:Transferrin