title: Increased antioxidant efficacy of tocopherols by surfactant solubilization in oil-in-water emulsions.
abstract: The physical location of antioxidants in oil-in-water emulsions can have significant influence on their free radical scavenging activity and ability to inhibit lipid oxidation. We aimed to determine the effect of the surfactant concentration on the partitioning behavior of tocopherols (α, γ, and δ) in oil-in-water emulsions. Tween 20 (0.1, 0.5, and 1%) increased the partitioning of the tocopherols into the aqueous phase via the formation of Tween 20-tocopherol comicelles. Partitioning behavior of antioxidants was dependent upon the number of methyl groups and, thus, polarity of the tocopherols. δ-Tocopherol (one methyl group) exhibited the most partitioning into the aqueous phase, while α-tocopherol (three methyl groups) had the lowest partitioning. Lipid oxidation studies showed that the antioxidant activity of δ- and α-tocopherols was enhanced by adding Tween 20 to oil-in-water emulsions. This work suggests that surfactant micelles could increase the antioxidant activity of tocopherols by changing their physical location.
authors.affiliation: Department of Food Science, University of Massachusetts Amherst , 240 Chenoweth Laboratory, 100 Holdsworth Way, Amherst, Massachusetts 01003, United States.
authors.forename: S Sezer
authors.initials: SS
authors.lastname: Kiralan
authors.forename: Esra
authors.initials: E
authors.lastname: Doğu-Baykut
authors.forename: Ketinun
authors.initials: K
authors.lastname: Kittipongpittaya
authors.forename: David Julian
authors.initials: DJ
authors.lastname: McClements
authors.forename: Eric A
authors.initials: EA
authors.lastname: Decker
mesh_terms: D000975:Antioxidants / Q000737:chemistry*; D004655:Emulsions / Q000737:chemistry; D012995:Solubility; D013024:Soybean Oil / Q000737:chemistry; D013501:Surface-Active Agents / Q000737:chemistry*; D024505:Tocopherols / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D000975:Antioxidants; D004655:Emulsions; D013501:Surface-Active Agents; D014867:Water; D013024:Soybean Oil; D024505:Tocopherols
keywords: antioxidant; lipid oxidation; oil-in-water emulsion; surfactant; tocopherol