title: Single nucleotide polymorphism within arylsulfatase D gene (ARSD) is associated with selected kinematic parameters of sperm motility in Holstein-Friesian bulls.
abstract: The aim of the study was to find out whether the single nucleotide polymorphism (SNP) within arylsulfatase D (ARSD) gene is associated with kinematic parameters of sperm motility in Holstein-Friesian bulls. 367 Holstein-Friesian bulls kept in one AI center were included in the study. Point mutation C/T at position 139037255 on chromosome X (rs42207167) was identified by PCR-RFLP method (Pflm I). Significant associations were found between ARSD genotypes and CASA-derived sperm motility parameters: average TM (Total Motility), average VSL (Straight Velocity), average VCL (Curvilinear Velocity) and for fraction of sperms showing progressive motility (a) of sperms (VSLa, VCLa and BCFa -Beat Cross Frequency). Most significant differences were observed between alternative homozygotes (CC vs TT). Our results suggest new role of arylsulfatase D gene as being involved in sperm motility.
authors.forename: D
authors.initials: D
authors.lastname: Hering
authors.forename: M
authors.initials: M
authors.lastname: Lecewicz
authors.forename: W
authors.initials: W
authors.lastname: Kordan
authors.forename: S
authors.initials: S
authors.lastname: Kaminski
mesh_terms: D000818:Animals; D001192:Arylsulfatases / Q000235:genetics / Q000378:metabolism*; D002417:Cattle / Q000235:genetics* / Q000502:physiology*; D015971:Gene Expression Regulation, Enzymologic; D008297:Male; D020641:Polymorphism, Single Nucleotide; D013081:Sperm Motility / Q000502:physiology*; D013094:Spermatozoa / Q000201:enzymology*
chemical_list: D001192:Arylsulfatases