title: Sunflower oil mediated biomimetic synthesis and cytotoxicity of monodisperse hexagonal silver nanoparticles.
abstract: In this work, sunflower oil was utilized for the biomimetic synthesis of silver (Ag) nanoparticles (NPs), leading to highly mono-dispersed hexagonal-shaped silver nanoparticles (NPs) at various concentrations. It was found that the biomolecules of the oil not only have the capability to reduce silver ions, due to its extended phenolic system, but also appear to recognize and affect the Ag nanocrystal growth on the (110) face, leading to hexagonal growth of the NPs of 50 nm size. Initially, some spherical AgNPs of less than 10nm diameter were observed; however, over a longer period of time, a majority of hexagonal-shaped nanocrystals were formed. The one step synthesis can be extended for other metals. The as prepared sunflower oil capped AgNPs being completely free of toxic chemicals can be directly utilized for in vitro studies and offer a more rational approach for cellular applications. The NP solution exhibited dose-dependent cytotoxicity in human lung carcinoma cells and physiologically relevant cell model (3T3L1 cells).
authors.affiliation: Department of Chemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara 390002, Gujarat, India. Electronic address: chemistry2797@yahoo.com.
authors.forename: Sonal
authors.initials: S
authors.lastname: Thakore
authors.affiliation: Department of Chemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara 390002, Gujarat, India.
authors.forename: Puran Singh
authors.initials: PS
authors.lastname: Rathore
authors.affiliation: Department of Zoology, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara 390002, Gujarat, India.
authors.forename: Ravirajsinh N
authors.initials: RN
authors.lastname: Jadeja
authors.affiliation: Department of Zoology, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara 390002, Gujarat, India.
authors.forename: Menaka
authors.initials: M
authors.lastname: Thounaojam
authors.affiliation: Department of Zoology, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara 390002, Gujarat, India.
authors.forename: Ranjitsinh V
authors.initials: RV
authors.lastname: Devkar
mesh_terms: D041721:3T3-L1 Cells; D000818:Animals; D032701:Biomimetics / Q000379:methods*; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D053768:Metal Nanoparticles / Q000737:chemistry*; D051379:Mice; D046529:Microscopy, Electron, Transmission; D010316:Particle Size; D010938:Plant Oils / Q000737:chemistry*; D017382:Reactive Oxygen Species; D012834:Silver; D018030:Silver Compounds / Q000737:chemistry*; D012996:Solutions; D017550:Spectroscopy, Fourier Transform Infrared; D000074242:Sunflower Oil
chemical_list: D010938:Plant Oils; D017382:Reactive Oxygen Species; D018030:Silver Compounds; D012996:Solutions; D000074242:Sunflower Oil; D012834:Silver
keywords: Biosynthesis; Cytotoxicity; Hexagonal nanoparticles; Silver nanoparticles; Sunflower oil