title: [Percutaneous closure of the left atrial appendage for stroke prevention].
abstract: In patients with atrial fibrillation (AF) and increased risk of stroke, oral anticoagulation (OAC) is the standard treatment for stroke prevention - however, this therapy also carries a high risk of bleeding. Percutaneous closure of the left atrial appendage (LAA) has been suggested to be an alternative option for stroke prevention in AF patients with contraindication(s) for OAC treatment. In this paper, we discuss the rationale for LAA closure, the importance of a proper patient selection, as well as some pre- and post-procedural issues.
authors.affiliation: Kardiologisk Klinik, Rigshospitalet, Blegdamsvej 9, 2100 København Ø. anastasiacool1@gmail.com.
authors.forename: Anastasia M
authors.initials: AM
authors.lastname: Loupis
authors.forename: Ole
authors.initials: O
authors.lastname: De Backer
authors.forename: Nikolaj
authors.initials: N
authors.lastname: Ihlemann
authors.forename: Tine S
authors.initials: TS
authors.lastname: Rosenberg
authors.forename: Olaf W
authors.initials: OW
authors.lastname: Franzen
authors.forename: Lars
authors.initials: L
authors.lastname: Søndergaard
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use; D020517:Atrial Appendage / Q000601:surgery*; D001281:Atrial Fibrillation / Q000150:complications; D006328:Cardiac Catheterization / Q000295:instrumentation / Q000379:methods*; D000075203:Contraindications, Drug; D006801:Humans; D018579:Patient Selection; D018570:Risk Assessment; D012307:Risk Factors; D020521:Stroke / Q000517:prevention & control*
chemical_list: D000925:Anticoagulants