title: I2-mediated oxidative cyclization for synthesis of substituted indolizines.
abstract: A direct method for the synthesis of substituted indolizines by means of I2-mediated oxidative tandem cyclization via C-N/C-C bond formation was developed. Various substituted aromatic/aliphatic enolizable aldehydes and 2-pyridylacetates/acetonitrile/acetone proceeded smoothly in this transformation, and the desired products were generated in moderate to good yields.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Department of Chemistry, Lanzhou University , Lanzhou 730000, China.
authors.forename: Likui
authors.initials: L
authors.lastname: Xiang
authors.forename: Yang
authors.initials: Y
authors.lastname: Yang
authors.forename: Xiaoqiang
authors.initials: X
authors.lastname: Zhou
authors.forename: Xingxing
authors.initials: X
authors.lastname: Liu
authors.forename: Xiaoni
authors.initials: X
authors.lastname: Li
authors.forename: Xing
authors.initials: X
authors.lastname: Kang
authors.forename: Rulong
authors.initials: R
authors.lastname: Yan
authors.forename: Guosheng
authors.initials: G
authors.lastname: Huang
mesh_terms: D000097:Acetonitriles / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007212:Indolizines / Q000138:chemical synthesis* / Q000737:chemistry; D007455:Iodine / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011725:Pyridines / Q000737:chemistry*
chemical_list: D000097:Acetonitriles; D007212:Indolizines; D011725:Pyridines; D007455:Iodine