title: Extracellular ATP, a danger signal, is recognized by DORN1 in Arabidopsis.
abstract: ATP, the universal energy currency of all organisms, is released into the extracellular matrix and serves as a signal among cells, where it is referred to as an extracellular ATP. Although a signalling role for extracellular ATP has been well studied in mammals over the last 40 years, investigations of such a role in plants are at an early stage. Recently, the first plant receptor for extracellular ATP, DOes not Respond to Nucleotides (DORN1), was identified in Arabidopsis thaliana by mutant screening. DORN1 encodes a legume-type lectin receptor kinase that is structurally distinct from the mammalian extracellular ATP receptors. In the present review, we highlight the genetic and biochemical evidence for the role of DORN1 in extracellular ATP signalling, placing this within the wider context of extracellular ATP signalling during plant stress responses.
authors.affiliation: *Divisions of Biochemistry and Plant Sciences, Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, U.S.A.
authors.forename: Jeongmin
authors.initials: J
authors.lastname: Choi
authors.affiliation: *Divisions of Biochemistry and Plant Sciences, Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, U.S.A.
authors.forename: Kiwamu
authors.initials: K
authors.lastname: Tanaka
authors.affiliation: *Divisions of Biochemistry and Plant Sciences, Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, U.S.A.
authors.forename: Yan
authors.initials: Y
authors.lastname: Liang
authors.affiliation: *Divisions of Biochemistry and Plant Sciences, Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, U.S.A.
authors.forename: Yangrong
authors.initials: Y
authors.lastname: Cao
authors.affiliation: †Plant Molecular Biology & Biotechnology Research Center (PMBBRC), Gyeongsang National University, Bd. 6-421, Jinjudaero 501, JinJu, Gyeongsangnam-do 660-701, South Korea.
authors.forename: Sang Yeol
authors.initials: SY
authors.lastname: Lee
authors.affiliation: *Divisions of Biochemistry and Plant Sciences, Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, U.S.A.
authors.forename: Gary
authors.initials: G
authors.lastname: Stacey
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism*; D017360:Arabidopsis / Q000276:immunology / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000378:metabolism*; D005110:Extracellular Space / Q000378:metabolism*; D057865:Plant Immunity; D037121:Plant Lectins / Q000378:metabolism; D011494:Protein Kinases / Q000378:metabolism*; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D017434:Protein Structure, Tertiary; D013312:Stress, Physiological
chemical_list: D029681:Arabidopsis Proteins; D037121:Plant Lectins; D000255:Adenosine Triphosphate; C586088:LecRK-I.9 protein, Arabidopsis; D011494:Protein Kinases; D017346:Protein Serine-Threonine Kinases