title: [Severe sepsis and septic shock].
abstract: Sepsis, severe sepsis and septic shock are syndromes. The incidence of sepsis is as high as 35% and with mortality rates in the intensive care unit from 27% to 54% in sepsis and septic shock, respectively. Many new treatments have been tested but only few have been implemented in clinical practise. The treatment of severe sepsis and septic shock is based on the Surviving Sepsis Campaign guidelines developed by an international expert panel. Early diagnosis, optimization of haemodynamics, rapid identification of focus and adequate antibiotic treatment are the most important strategies.
authors.affiliation: Anæstesiologisk Afdeling, Aarhus Universitetshospital, Nørrebrogade 44, 8000 Aarhus C. elsetoen@rm.dk.
authors.forename: Else
authors.initials: E
authors.lastname: Tønnesen
authors.forename: Kim
authors.initials: K
authors.lastname: Larsen
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D042241:Early Diagnosis; D019317:Evidence-Based Medicine; D006801:Humans; D017410:Practice Guidelines as Topic; D018805:Sepsis / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy; D012772:Shock, Septic / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy
chemical_list: D000900:Anti-Bacterial Agents