title: Traditional Chinese medicine for treatment of liver diseases: progress, challenges and opportunities.
abstract: Traditional Chinese medicine (TCM) is commonly used in treating liver diseases worldwide, especially in China. The advantages of using TCM for treatment of liver diseases include: protecting hepatocytes, inhibiting hepatic inflammation and antifibrosis in the liver. In this article, we introduce TCM herbal preparations from the Chinese materia medica (such as Fuzheng Huayu) that are typically used for the treatment of liver diseases. Literature surrounding the mechanisms of TCM therapy for treatment of liver diseases is presented and discussed. We propose that side effects of herbal compounds are often under-appreciated, and that more care should be taken in the prescription of potentially hepatotoxic medicines. Further, to deepen the understanding of TCM mechanisms, new techniques and methodologies must be developed. Future studies will lead to the enhancement of clinical outcomes of TCM. As complementary and alternative therapies, TCMs will play an expanding role in the future of liver disease treatment.
authors.affiliation: Department of Liver Cirrhosis, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
authors.forename: Chang-qing
authors.initials: CQ
authors.lastname: Zhao
authors.affiliation: Department of Liver Cirrhosis, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Institute of Liver Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Ping
authors.affiliation: Institute of Liver Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; E-mail: xulieming@126.com.
authors.forename: Lie-ming
authors.initials: LM
authors.lastname: Xu
mesh_terms: D056486:Chemical and Drug Induced Liver Injury / Q000517:prevention & control; D006801:Humans; D008107:Liver Diseases / Q000188:drug therapy*; D008419:Materia Medica / Q000627:therapeutic use; D008516:Medicine, Chinese Traditional
chemical_list: D008419:Materia Medica