title: Inductive and differentiative signals delivered by C8-substituted guanine ribonucleosides.
abstract: The C8-substituted guanine ribonucleosides area recently described class of immunomodulator which among a variety of pleiotropic effects have T-cell-replacing activity in vitro and immunopotentiating activity in immunocompromised hosts. In this article Michael Goodman discusses the mechanism of nucleoside transport, the immunobiologic activities of these compounds, and the nature of the cellular interactions involved.
authors.affiliation: Department of Immunology IMM9, Scripps Clinic and Research Foundation 10666 N. Torrey Pines Road, La Jolla, CA 92037, USA.
authors.forename: M G
authors.initials: MG
authors.lastname: Goodman