title: Number of mediastinal lymph nodes as a prognostic factor in PN2 non small cell lung cancer: a single centre experience and review of the literature.
abstract: Currently the most important prognostic factor in lung cancer is the stage. In the current lung TNM classification system, N category is defined exclusively by anatomic nodal location though, in other type of tumours, number of lymph nodes is confirmed to be a fundamental prognostic factor. Therefore we evaluated the number of mediastinal lymph nodes as a prognostic factor in locally advanced NSCLC after multimodality treatment, observing a significant effect of the number of lymph nodes in terms of OS (p<0.01) and DFS (p<0.001): patients with a low number of positive mediastinal nodes have a better prognosis.
authors.affiliation: Department of Radiation Oncology, Azienda Policlinico Umberto I, "Sapienza" University of Rome. Viale del Policlinico Italy E-mail : silvia.takanen@gmail.com.
authors.forename: Silvia
authors.initials: S
authors.lastname: Takanen
authors.forename: Caterina
authors.initials: C
authors.lastname: Bangrazi
authors.forename: Vanessa
authors.initials: V
authors.lastname: Graziano
authors.forename: Alessandro
authors.initials: A
authors.lastname: Parisi
authors.forename: Blerina
authors.initials: B
authors.lastname: Resuli
authors.forename: Luca
authors.initials: L
authors.lastname: Simione
authors.forename: Rossella
authors.initials: R
authors.lastname: Caiazzo
authors.forename: Nicola
authors.initials: N
authors.lastname: Raffetto
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Tombolini
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality / Q000556:secondary* / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology* / Q000628:therapy; D008207:Lymphatic Metastasis; D008297:Male; D008479:Mediastinal Neoplasms / Q000401:mortality / Q000556:secondary* / Q000628:therapy; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D012196:Review Literature as Topic; D015996:Survival Rate