title: Chemical structures of constituents from the flowers of Osmanthus fragrans var. aurantiacus.
abstract: Three new megastigmane glycosides named floraosmanosides I-III and a new γ-decalactone named floraosmanolactone I together with 16 known constituents were isolated from the flowers of Osmanthus fragrans var. aurantiacus cultivated in Guangxi Zhuang Autonomous Region, China. The chemical structures of the new compounds were elucidated on the basis of chemical and physicochemical evidence. Among them, ligustroside and (+)-pinoresinol significantly inhibited nitric oxide production in lipopolysaccharide-activated RAW264.7 macrophages.
authors.affiliation: Key Laboratory of Crop Ecophysiology and Farming System in Southwest China, Ministry of Agriculture, Sichuan Agricultural University, Chengdu, 611130, People's Republic of China.
authors.forename: Jiang
authors.initials: J
authors.lastname: Liu
authors.forename: Seikou
authors.initials: S
authors.lastname: Nakamura
authors.forename: Bin
authors.initials: B
authors.lastname: Xu
authors.forename: Takahiro
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Tomoe
authors.initials: T
authors.lastname: Ohta
authors.forename: Katsuyoshi
authors.initials: K
authors.lastname: Fujimoto
authors.forename: Keiko
authors.initials: K
authors.lastname: Ogawa
authors.forename: Masashi
authors.initials: M
authors.lastname: Fukaya
authors.forename: Shiori
authors.initials: S
authors.lastname: Miyake
authors.forename: Masayuki
authors.initials: M
authors.lastname: Yoshikawa
authors.forename: Hisashi
authors.initials: H
authors.lastname: Matsuda
mesh_terms: D000818:Animals; D002460:Cell Line; D035264:Flowers / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D008264:Macrophages / Q000187:drug effects / Q000378:metabolism; D009569:Nitric Oxide / Q000096:biosynthesis; D029592:Oleaceae / Q000737:chemistry*
chemical_list: D006027:Glycosides; D009569:Nitric Oxide