title: Residue dissipation and processing factor for dimethomorph, famoxadone and cymoxanil during raisin preparation.
abstract: A method was validated for the simultaneous analysis of the residues of dimethomorph, famoxadone and cymoxanil in grape and raisin matrix by ethyl acetate based extraction and liquid chromatography tandem mass spectrometric analysis. Field studies were conducted to evaluate the dissipation rate kinetics and processing factor (PF) for these pesticides during raisin making. Residue data during the drying process were best fitted to 1st+1st order rate kinetics with half-life ranging between 8-9 days for dimethomorph, 12-13 days for famoxadone and 9-10 days for cymoxanil at single dose (SD) and double dose (DD), respectively. PF values calculated were 1.03 and 1.14 for dimethomorph, 1.95 and 2.09 for famoxadone, and 1.99 and 1.35 for cymoxanil at SD and DD, respectively. PF value >1 indicates concentration of the residues during raisin making. The residues of detected pesticides in market samples of raisins were devoid of any risk of acute toxicity related to dietary exposure.
authors.affiliation: National Referral Laboratory, National Research Centre for Grapes, P.O. Manjri Farm, Pune 412 307, India.
authors.forename: Ahammed
authors.initials: A
authors.lastname: Shabeer T P
authors.affiliation: National Referral Laboratory, National Research Centre for Grapes, P.O. Manjri Farm, Pune 412 307, India. Electronic address: kbgrape@yahoo.com.
authors.forename: Kaushik
authors.initials: K
authors.lastname: Banerjee
authors.affiliation: National Referral Laboratory, National Research Centre for Grapes, P.O. Manjri Farm, Pune 412 307, India.
authors.forename: Manjusha
authors.initials: M
authors.lastname: Jadhav
authors.affiliation: National Referral Laboratory, National Research Centre for Grapes, P.O. Manjri Farm, Pune 412 307, India.
authors.forename: Rushali
authors.initials: R
authors.lastname: Girame
authors.affiliation: National Referral Laboratory, National Research Centre for Grapes, P.O. Manjri Farm, Pune 412 307, India.
authors.forename: Sagar
authors.initials: S
authors.lastname: Utture
authors.affiliation: National Referral Laboratory, National Research Centre for Grapes, P.O. Manjri Farm, Pune 412 307, India.
authors.forename: Sandip
authors.initials: S
authors.lastname: Hingmire
authors.affiliation: National Referral Laboratory, National Research Centre for Grapes, P.O. Manjri Farm, Pune 412 307, India.
authors.forename: Dasharath
authors.initials: D
authors.lastname: Oulkar
mesh_terms: D000081:Acetamides / Q000737:chemistry*; D002853:Chromatography, Liquid / Q000379:methods*; D013058:Mass Spectrometry / Q000379:methods*; D008689:Methacrylates / Q000737:chemistry; D009025:Morpholines / Q000737:chemistry*; D010080:Oxazoles / Q000737:chemistry*; D000073739:Strobilurins; D027843:Vitis / Q000737:chemistry*
chemical_list: D000081:Acetamides; D008689:Methacrylates; D009025:Morpholines; D010080:Oxazoles; D000073739:Strobilurins; C076154:dimethomorph; C025644:2-cyano-N-((ethylamino)carbonyl)-2-(methoxyimino)acetamide; C401929:famoxadone
keywords: Cymoxanil; Dissipation of dimethomorph; Famoxadone; LC–MS/MS method validation; Processing factor; Residues in raisin