title: Connective tissue graft as a biological barrier for guided tissue regeneration in intrabony defects: a histological study in dogs.
abstract: BACKGROUND
  The use of the autogenous periosteal graft as biological barrier has been proposed for periodontal regeneration. The aim of this study was to evaluate the histometric findings of the subepithelial connective tissue graft as barrier in intrabony defects compared to a bioabsorbable membrane.
  
  
  METHODS
  Three-walled intrabony defects were created surgically in the mesial aspect of the right and left maxillary canines in five healthy mongrel dogs. The defects were chronified, and two types of barriers were randomly carried out for guided tissue regeneration in a split-mouth design: the test group with a subepithelial connective tissue graft and the control group with a bioabsorbable membrane. The specimens were processed for histometric analyses of the epithelium (E), connective tissue (CT), newly formed cementum (NC), new bone (NB), and total newly formed tissues (NFT).
  
  
  RESULTS
  The test side showed smaller mean of NC (3.6 ± 1.2), NB (2.1 ± 0.7), and NFT (7.7 ± 0.8) than the control group (NC 7.3 ± 0.5; NB 5.3 ± 1.3; NFT 10.1 ± 2.2; P < 0.05). No statistically significant differences were verified for E (test 3.1 ± 2.0; control 2.8 ± 2.1; P > 0.05) and CT (test 2.5 ± 1.1; control 2.0 ± 0.5; P > 0.05) between groups.
  
  
  CONCLUSIONS
  The bioabsorbable membrane was more effective in maintaining the space for periodontal regeneration than periosteal connective graft when used as barrier.
  
  
  CONCLUSIONS
  The bioabsorbable membrane showed more favorable regenerative results in intrabony defects in dogs than the subepithelial connective tissue graft as biological barrier.
authors.affiliation: Department of Master in Dental Sciences, School of Dentistry, Educational Foundation of Barretos (UNIFEB), Av. Prof. Roberto Frade Monte, 389. Jd. Aeroporto, 14783-226, Barretos, SP, Brazil, fernandosalimon@yahoo.com.br.
authors.forename: Fernando Salimon
authors.initials: FS
authors.lastname: Ribeiro
authors.forename: Ana Emília Farias
authors.initials: AE
authors.lastname: Pontes
authors.forename: Elizangela Partata
authors.initials: EP
authors.lastname: Zuza
authors.forename: Vanessa Camila
authors.initials: VC
authors.lastname: da Silva
authors.forename: Raphael Carlos Comelli
authors.initials: RC
authors.lastname: Lia
authors.forename: Elcio
authors.initials: E
authors.lastname: Marcantonio Junior
mesh_terms: D020341:Absorbable Implants; D000818:Animals; D001672:Biocompatible Materials; D001861:Bone Regeneration; D003238:Connective Tissue / Q000637:transplantation*; D004285:Dogs; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods*; D008437:Maxilla / Q000601:surgery*; D008567:Membranes, Artificial
chemical_list: D001672:Biocompatible Materials; D008567:Membranes, Artificial