title: Recurrent case of central giant cell granuloma with multiple soft tissue involvement.
abstract: Central giant cell granuloma is a fairly common lesion in the jaws aetiology of which is still completely unknown but thought to be of a reactive process to some unknown stimuli. It usually arises either peripherally in periodontal ligament, mucoperiosteum, or centrally in the bone. The histological hallmark for both peripheral and central giant cell granuloma (CGCG) is the presence of distinctive multinucleated giant cells (MGCs) in a prominent fibrous stroma. Central giant cell granuloma is an uncommon benign proliferative lesion that almost exclusively occurs within the jaw. Eventually, it may become aggressive leading to the expansion and perforation of cortex resulting into mobility and displacement of teeth with root resorption. The present case focuses on the dilemma and perplexity in diagnosing aggressive CGCGs, due to its close proximity with respect to pathology, behavior and prognosis from giant cell tumors (GCT). Central giant cell granuloma persuaded extensive destruction to the hard and soft tissues with high rate of recurrence encourage us the need of exploring the possibilities of giant cell tumors having a definitive presence in the jaws.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Kalka Dental College and Hospital, Meerut, Uttar Pradesh, India.
authors.forename: Suresh
authors.initials: S
authors.lastname: Yadav
authors.affiliation: Department of Oral and Maxillofacial Surgery, ITS Dental College, Ghaziabad, Uttar Pradesh, India.
authors.forename: Anurag
authors.initials: A
authors.lastname: Singh
authors.affiliation: Department of Prosthodontics and Oral Implantology, Shree Bankey Bihari Dental College and Research Centre, Ghaziabad, Uttar Pradesh, India.
authors.forename: Prince
authors.initials: P
authors.lastname: Kumar
authors.affiliation: Department of Pedodontics and Preventive Dentistry, Kalka Dental College and Hospital, Meerut, Uttar Pradesh, India.
authors.forename: Shallu
authors.initials: S
authors.lastname: Tyagi
keywords: Giant cells; giant cell granuloma; unilocular radiolucency