title: A clinical scoring system to predict the development of bronchopulmonary dysplasia.
abstract: OBJECTIVE
  This study aims to develop a scoring system for the prediction of bronchopulmonary dysplasia (BPD).
  
  
  METHODS
  Medical records of 652 infants whose gestational age and birth weight were below 32 weeks and 1,500 g, respectively, and who survived beyond 28th postnatal day were reviewed retrospectively. Logistic regression methods were used to determine the clinical and demographic risk factors within the first 72 hours of life associated with BPD, as well as the weights of these factors on developing BPD. Predictive accuracy of the scoring system was tested prospectively at the same unit.
  
  
  RESULTS
  Birth weight, gestational age, gender, presence of respiratory distress syndrome, patent ductus arteriosus, intraventricular hemorrhage, hypotension were the most important risk factors for BPD. Therefore, a scoring system (BPD-TM score) ranging from 0 to 13 and grouped in four tiers (0-3: low, 4-6: low intermediate, 7-9: high intermediate, and 10-13: high risk) was developed based on these factors. Below the score of 4, 4.1% of infants (18/436), above the score of 9, 100% (29/29) of the infants developed BPD. The score was validated successfully in 172 infants.
  
  
  CONCLUSIONS
  With this easy to use scoring system, one can predict the neonate at risk for BPD at 72 hours of life and direct preventive measures toward these infants.
authors.affiliation: Department of Neonatology, School of Medicine, KOC University, Istanbul, Turkey.
authors.forename: Tugba
authors.initials: T
authors.lastname: Gursoy
authors.affiliation: Department of Preventive Oncology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
authors.forename: Mutlu
authors.initials: M
authors.lastname: Hayran
authors.affiliation: Department of Pediatrics, Zeynep Kamil Maternity and Children's Research and Training Hospital, Istanbul, Turkey.
authors.forename: Hatice
authors.initials: H
authors.lastname: Derin
authors.affiliation: Department of Pediatrics, Zeynep Kamil Maternity and Children's Research and Training Hospital, Istanbul, Turkey.
authors.forename: Fahri
authors.initials: F
authors.lastname: Ovali
mesh_terms: D001724:Birth Weight; D001997:Bronchopulmonary Dysplasia / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D002543:Cerebral Hemorrhage / Q000453:epidemiology; D002552:Cerebral Ventricles; D003661:Decision Support Techniques; D004374:Ductus Arteriosus, Patent / Q000453:epidemiology; D005260:Female; D005865:Gestational Age; D006801:Humans; D007022:Hypotension / Q000453:epidemiology; D007231:Infant, Newborn; D008297:Male; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012372:ROC Curve; D012127:Respiratory Distress Syndrome, Newborn / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors