title: [Hypersexuality associated with aripiprazole: a new case and review of the literature].
abstract: We report the case of a patient with hypersexuality while he was treated with aripiprazole since 6 months. Clinical manifestations were an increased libido, unusual frequent masturbation and sexual instincts. All have resolved upon discontinuation of aripiprazole, and recurred after it was restarted. The partial dopaminergic agonist effect of aripiprazole could probably explain the occurrence of this compulsive behaviour.
authors.affiliation: Centre régional de pharmacovigilance, de pharmacoépidémiologie et d'information sur le médicament, Service de pharmacologie clinique, CHRU de Tours, Tours, France.
authors.forename: Laura
authors.initials: L
authors.lastname: Vrignaud
authors.affiliation: Cabinet de psychiatrie, Tours, France.
authors.forename: Jerémie
authors.initials: J
authors.lastname: Aouille
authors.affiliation: Centre régional de pharmacovigilance, CHU de Grenoble, Grenoble, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Mallaret
authors.affiliation: Service de pharmacologie médicale et clinique, Centre Midi-Pyrénées de pharmacovigilance, de pharmacoépidémiologie et d'informations sur le médicament, CHU de Toulouse et Faculté de médecine, Toulouse, France.
authors.forename: Geneviève
authors.initials: G
authors.lastname: Durrieu
authors.affiliation: Centre régional de pharmacovigilance, de pharmacoépidémiologie et d'information sur le médicament, Service de pharmacologie clinique, CHRU de Tours, Tours, France.
authors.forename: Annie-Pierre
authors.initials: AP
authors.lastname: Jonville-Béra
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D000068180:Aripiprazole; D006801:Humans; D007989:Libido / Q000187:drug effects*; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000139:chemically induced / Q000175:diagnosis; D010879:Piperazines / Q000009:adverse effects*; D015363:Quinolones / Q000009:adverse effects*; D012559:Schizophrenia / Q000188:drug therapy; D012735:Sexual Dysfunction, Physiological / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D014150:Antipsychotic Agents; D010879:Piperazines; D015363:Quinolones; D000068180:Aripiprazole