title: Equine herpesvirus 1 myeloencephalopathy.
abstract: Equine myeloencephalopathy (EHM), an uncommon manifestation of equine herpesvirus 1 (EHV-1) infection, can cause devastating losses on individual farms, boarding stables, veterinary hospitals, and show and racing venues. An improved understanding of EHM has emerged from experimental studies and from data collected during field outbreaks at riding schools, racetracks, horse shows, and veterinary hospitals throughout North America and Europe. These outbreaks have highlighted the contagious nature of EHV-1 and have prompted a reevaluation of diagnostic procedures, treatment modalities, preventative measures, and biosecurity protocols for this disease. This article focuses on recent data related to the cause, epidemiology, pathogenesis, immunity, diagnosis, treatment, and prevention of EHV-1 infection with emphasis on EHM.
authors.affiliation: Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, CA 95616, USA. Electronic address: npusterla@ucdavis.edu.
authors.forename: Nicola
authors.initials: N
authors.lastname: Pusterla
authors.affiliation: Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, 736 Wilson Road, East Lansing, MI 48824, USA.
authors.forename: Gisela Soboll
authors.initials: GS
authors.lastname: Hussey
mesh_terms: D000818:Animals; D004196:Disease Outbreaks / Q000662:veterinary; D005060:Europe / Q000453:epidemiology; D006566:Herpesviridae Infections / Q000453:epidemiology / Q000628:therapy / Q000662:veterinary* / Q000821:virology; D004861:Herpesvirus 1, Equid / Q000302:isolation & purification*; D006734:Horse Diseases / Q000453:epidemiology / Q000628:therapy / Q000821:virology*; D006736:Horses; D009656:North America / Q000453:epidemiology
keywords: Clinical signs; Diagnosis; Epidemiology; Equine herpesvirus 1; Equine herpesvirus myeloencephalopathy; Etiology; Pathogenesis; Treatment