title: Imaging diagnosis for left ventricular thrombosis in idiopathic hypereosinophilic syndrome: two case reports.
abstract: Idiopathic hypereosinophilic syndrome (IHES) is a rare disease that is frequently associated with cardiac thrombosis and endocardial wall thickness. This case report describes 2 patients who had IHES associated with left ventricular (LV) thrombi. The patients' symptoms are atypical. Peripheral blood and bone marrow tests showed markedly elevated eosinophils. Electrocardiography showed ischemic changes in both patients. Negative computed tomography (CT) angiography excluded coronary artery stenosis. Transthoracic echocardiography (TTE), conventional multislice spiral CT, gemstone spectral CT, and cardiac magnetic resonance imaging were used to identify the LV intraluminal thrombus and endocardial thickening, and the diagnostic values of each imaging method were analyzed and compared. These patients were clinically diagnosed as "IHES, LV thrombosis, NYHA heart function classification I." Both patients received oral prednisone and warfarin therapy. At 5 month follow-up, TTE rechecks showed that the size of the LV thrombotic lesion was reduced in the first case but substantially increased in the second case.
authors.affiliation: Division of Cardiology (Y-QH, Y-NZ, J-MZ, HZ, PY); and Division of Radiology (M-CZ, LL), China-Japan Union Hospital of Jilin University, Changchun, Jilin, China.
authors.forename: Yu-Quan
authors.initials: YQ
authors.lastname: He
authors.forename: Ya-Nan
authors.initials: YN
authors.lastname: Zhao
authors.forename: Jin-Ming
authors.initials: JM
authors.lastname: Zhu
authors.forename: Meng-Chao
authors.initials: MC
authors.lastname: Zhang
authors.forename: Lin
authors.initials: L
authors.lastname: Liu
authors.forename: Hong
authors.initials: H
authors.lastname: Zeng
authors.forename: Ping
authors.initials: P
authors.lastname: Yang
mesh_terms: D000328:Adult; D000792:Angiography; D004452:Echocardiography; D004562:Electrocardiography; D006331:Heart Diseases / Q000175:diagnosis* / Q000209:etiology; D006352:Heart Ventricles; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications*; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography; D013927:Thrombosis / Q000175:diagnosis* / Q000209:etiology; D014055:Tomography, Emission-Computed