title: [Anaesthetics and porphyria].
abstract: Patients with acute porphyria are at risk of life-threatening attacks when exposed to stress, fast, infection, alcohol and especially some drugs, including older anaesthetics. Acute porphyrias are rare inherited diseases caused by inefficient enzymatic activity within the haem synthesis. During attacks the patient suffers from severe abdominal pain, cardiovascular instability, neurological symptoms etc. Preventive measures and treatment should be known to anaesthesiologists and surgeons in particular and known to other clinicians in general. In order to assist the clinicians, drug databases are available online.
authors.affiliation: Jyllingevej 32, 1. tv, 2720 Vanløse. E-mail: signe@samlerikkepaakuglepenne.dk.
authors.forename: Signe
authors.initials: S
authors.lastname: Schjelde
authors.forename: Claus
authors.initials: C
authors.lastname: Lund
mesh_terms: D000208:Acute Disease; D000777:Anesthetics / Q000009:adverse effects*; D006418:Heme / Q000096:biosynthesis; D006801:Humans; D011164:Porphyrias / Q000139:chemically induced* / Q000201:enzymology; D018570:Risk Assessment
chemical_list: D000777:Anesthetics; D006418:Heme