title: [Clinical study on patients with renal-cell carcinoma accompanied with Von Hippel-Lindau disease treated with radiofrequency ablation].
abstract: We report 12 renal cell carcinomas in 6 patients with Von Hippel-Lindau (VHL) disease treated with radiofrequency ablation (RFA). The mean age of the patients was 46 (range 38-53) years (male : 4, female : 2). Computed tomography (CT)-guided transcutaneous RFA was performed under conscious sedation with local anesthetics. The mean size of the tumors was 2.4 (range 0.7-8.1) cm. Nine of the 12 tumors (75%) were locally well controlled. However, 3 tumors in 2 patients developed visceral metastases after RFA. While minimal flank pain, nausea, perinephritic hematoma and lumbago were observed, there was no major complication during or after the procedure. The therapy with CT-guided transcutaneous RFA is efficient and minimal invasive for renal cell carcinoma in patients with VHL, leading to preservation of renal function.
authors.affiliation: The Department of Urology, Kochi Medical School.
authors.forename: Tomoya
authors.initials: T
authors.lastname: Nao
authors.affiliation: The Department of Urology, Kochi Medical School.
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Shimamoto
authors.affiliation: The Department of Urology, Kochi Medical School.
authors.forename: Takashi
authors.initials: T
authors.lastname: Karashima
authors.affiliation: The Department of Urology, Kochi National Hospital.
authors.forename: Maiko
authors.initials: M
authors.lastname: Kamei
authors.affiliation: The Department of Urology, Kochi Medical School.
authors.forename: Hideo
authors.initials: H
authors.lastname: Fukuhara
authors.affiliation: The Department of Urology, Kochi Medical School.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Fukata
authors.affiliation: The Department of Urology, Kochi Medical School.
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Satake
authors.affiliation: The Department of Urology, Kochi Medical School.
authors.forename: Shingo
authors.initials: S
authors.lastname: Ashida
authors.affiliation: The Department of Urology, Kochi Medical School.
authors.forename: Ichiro
authors.initials: I
authors.lastname: Yamasaki
authors.affiliation: The Department of Urology, Kochi Medical School.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Kamata
authors.affiliation: The Department of Urology, Kochi Medical School.
authors.forename: Keiji
authors.initials: K
authors.lastname: Inoue
authors.affiliation: The Department of Diagnostic Radiology and Radiation Oncology, Kochi Medical School.
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Yamanishi
authors.affiliation: The Department of Diagnostic Radiology and Radiation Oncology, Kochi Medical School.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Ogawa
authors.affiliation: The Department of Diagnostic Radiology, Kochi Red Cross Hospital.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ito
authors.affiliation: The Department of Urology, Kochi Medical School.
authors.forename: Taro
authors.initials: T
authors.lastname: Shuin
mesh_terms: D000328:Adult; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D017115:Catheter Ablation; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed; D006623:von Hippel-Lindau Disease / Q000150:complications*