title: Multiple brain tuberculomas in a 32-year-old woman with chronic headache.
abstract: Tuberculosis (TB) has re-emerged in the two past decades as a major health problem worldwide. Presently, more than 2 billion people (one third of the world population) are infected with TB, of which approximately 10% will develop the clinical disease. The incidence of central nervous system (CNS) TB is related to the prevalence of TB in the community, and it is still the most common type of chronic CNS infection in developing countries. We describe a 32-year-old woman, who presented with chronic headache, followed by gaze palsy and decreased level of consciousness. The disease was diagnosed through TB PCR of the cerebrospinal fluid (CSF). Anti TB drugs and corticosteroid were started for her and she responded successfully to treatment. We conclude that TB of CNS should be considered in patients with chronic headache, particularly in endemic regions because its diagnosis may be missed.
authors.affiliation: Infectious Diseases Specialist, Assistant Professor, Razi Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.feizi.j@gmail.com.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Ahmadi
authors.affiliation: Infectious Diseases Specialist, Assistant Professor, Razi Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Roohangiz
authors.initials: R
authors.lastname: Nashibi
authors.affiliation: Infectious Diseases Resident, Razi Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Masih
authors.initials: M
authors.lastname: Naghieh
authors.affiliation: Infectious Diseases Resident, Razi Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Jalil
authors.initials: J
authors.lastname: Feizi
authors.affiliation: Department of Environmental Health Engineering, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Shirmardi
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D000328:Adult; D000995:Antitubercular Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001921:Brain / Q000000981:diagnostic imaging; D004359:Drug Therapy, Combination; D005260:Female; D020773:Headache Disorders / Q000209:etiology*; D006801:Humans; D059906:Neuroimaging; D014057:Tomography, X-Ray Computed; D016862:Tuberculoma, Intracranial / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy
chemical_list: D000305:Adrenal Cortex Hormones; D000995:Antitubercular Agents