title: Ancient humans and the origin of modern humans.
abstract: Recent advances in sequencing technologies and molecular methods have facilitated the sequencing of DNA from ancient human remains which has, in turn, provided unprecedented insight into human history. Within the past 4 years the genomes of Neandertals and Denisovans, as well as the genomes of at least two early modern humans, have been sequenced. These sequences showed that there have been several episodes of admixture between modern and archaic groups; including admixture from Neandertals into modern human populations outside of Africa, and admixture from Denisovans into modern human populations in Oceania. Recent results indicate that some of these introgressed regions may have been advantageous for modern humans as they expanded into new regions outside of Africa.
authors.affiliation: Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany. Electronic address: kelso@eva.mpg.de.
authors.forename: Janet
authors.initials: J
authors.lastname: Kelso
authors.affiliation: Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.
authors.forename: Kay
authors.initials: K
authors.lastname: Prüfer
mesh_terms: D000349:Africa; D000818:Animals; D004247:DNA / Q000737:chemistry / Q000145:classification / Q000235:genetics*; D019143:Evolution, Molecular; D015894:Genome, Human / Q000235:genetics*; D015186:Hominidae / Q000235:genetics*; D006801:Humans; D044349:Oceania; D010802:Phylogeny; D017422:Sequence Analysis, DNA
chemical_list: D004247:DNA