title: Hypervalent iodine-mediated oxygenation of N,N-diaryl tertiary amines: intramolecular functionalization of sp3 C-H bonds adjacent to nitrogen.
abstract: An intramolecular C(sp(3))-O bond formation has been achieved via PhI(OAc)2/NaN3-mediated oxygenation of N,N-diaryl tertiary amines. The appealing features of this method include mild reaction conditions, absence of heavy-metal catalysts, and the direct intramolecular functionalization of sp(3) C-H bonds adjacent to nitrogen.
authors.affiliation: School of Pharmaceutical Science and Technology, Tianjin University , Tianjin 300072, China.
authors.forename: Ningning
authors.initials: N
authors.lastname: Zhang
authors.forename: Ran
authors.initials: R
authors.lastname: Cheng
authors.forename: Daisy
authors.initials: D
authors.lastname: Zhang-Negrerie
authors.forename: Yunfei
authors.initials: Y
authors.lastname: Du
authors.forename: Kang
authors.initials: K
authors.lastname: Zhao
mesh_terms: D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D006860:Hydrogen Bonding; D007455:Iodine / Q000737:chemistry*; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*
chemical_list: D000588:Amines; D007455:Iodine; D009584:Nitrogen; D010100:Oxygen