title: A rare case of male breast cavernous-type angioleiomyoma.
abstract: Cutaneous leiomyomas of the breast are extremely rare, particularly in men. Leiomyomas are categorized into three groups: angioleiomyomas, pilar leiomyomas and genital leiomyomas. Angioleiomyomas, or vascular leiomyomas, are benign tumors arising from smooth muscle cells of arterial or venous walls. We report the case of a 70-year-old man who was admitted to the surgery unit because of a painful lump in the left periareolar region. Ultrasound investigation showed a well-delimited, hyperechogenic, inhomogeneous nodular lesion. The final diagnosis was made after surgical excision and pathological evaluation of the mass. The histological features and immunohistochemical profile, characterized by positive expression of the spindle-shaped tumor cells for desmin and smooth muscle actin and by positive expression of the endothelial cells of the vascular channels for pan-endothelial markers CD34 and CD31, confirmed the diagnosis of a cavernous-type angioleiomyoma.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Branca
authors.forename: Eleonora
authors.initials: E
authors.lastname: Irato
authors.forename: Valeria
authors.initials: V
authors.lastname: Barresi
authors.forename: Marialuisa
authors.initials: M
authors.lastname: De Marco
authors.forename: Fabio
authors.initials: F
authors.lastname: Guccione
authors.forename: Renato
authors.initials: R
authors.lastname: Palmeri
mesh_terms: D000368:Aged; D018229:Angiomyoma / Q000737:chemistry / Q000473:pathology; D018567:Breast Neoplasms, Male / Q000737:chemistry / Q000473:pathology; D006392:Hemangioma, Cavernous / Q000737:chemistry / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D016130:Immunophenotyping; D008297:Male; D011980:Receptors, Progesterone / Q000032:analysis
chemical_list: D011980:Receptors, Progesterone