title: NOVA: a software to analyze complexome profiling data.
abstract: CONCLUSIONS
  We introduce nova, a software for the analysis of complexome profiling data. nova supports the investigation of the composition of complexes, cluster analysis of the experimental data, visual inspection and comparison of experiments and many other features.
  
  
  METHODS
  nova is licensed under the Artistic License 2.0. It is freely available at http://www.bioinformatik.uni-frankfurt.de. nova requires at least Java 7 and runs under Linux, Microsoft Windows and Mac OS.
  
  
  BACKGROUND
  ina.koch@bioinformatik.uni-frankfurt.de.
authors.affiliation: Molecular Bioinformatics Group, Institute of Computer Science, Faculty of Computer Science and Mathematics, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Robert-Mayer-Str. 11-15, 60325 Frankfurt am Main, Germany, Molecular Bioenergetics Group, Medical School, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany, Functional Proteomics, SFB815 core unit, Medical School, Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany and Nijmegen Centre for Mitochondrial Disorders, Radboud University Medical Centre, 6525 GA, Nijmegen, The Netherlands.
authors.forename: Heiko
authors.initials: H
authors.lastname: Giese
authors.affiliation: Molecular Bioinformatics Group, Institute of Computer Science, Faculty of Computer Science and Mathematics, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Robert-Mayer-Str. 11-15, 60325 Frankfurt am Main, Germany, Molecular Bioenergetics Group, Medical School, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany, Functional Proteomics, SFB815 core unit, Medical School, Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany and Nijmegen Centre for Mitochondrial Disorders, Radboud University Medical Centre, 6525 GA, Nijmegen, The Netherlands.
authors.forename: Jörg
authors.initials: J
authors.lastname: Ackermann
authors.affiliation: Molecular Bioinformatics Group, Institute of Computer Science, Faculty of Computer Science and Mathematics, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Robert-Mayer-Str. 11-15, 60325 Frankfurt am Main, Germany, Molecular Bioenergetics Group, Medical School, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany, Functional Proteomics, SFB815 core unit, Medical School, Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany and Nijmegen Centre for Mitochondrial Disorders, Radboud University Medical Centre, 6525 GA, Nijmegen, The Netherlands Molecular Bioinformatics Group, Institute of Computer Science, Faculty of Computer Science and Mathematics, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Robert-Mayer-Str. 11-15, 60325 Frankfurt am Main, Germany, Molecular Bioenergetics Group, Medical School, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany, Functional Proteomics, SFB815 core unit, Medical School, Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany and Nijmegen Centre for Mitochondrial Disorders, Radboud University Medical Centre, 6525 GA, Nijmegen, The Netherlands.
authors.forename: Heinrich
authors.initials: H
authors.lastname: Heide
authors.affiliation: Molecular Bioinformatics Group, Institute of Computer Science, Faculty of Computer Science and Mathematics, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Robert-Mayer-Str. 11-15, 60325 Frankfurt am Main, Germany, Molecular Bioenergetics Group, Medical School, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany, Functional Proteomics, SFB815 core unit, Medical School, Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany and Nijmegen Centre for Mitochondrial Disorders, Radboud University Medical Centre, 6525 GA, Nijmegen, The Netherlands.
authors.forename: Lea
authors.initials: L
authors.lastname: Bleier
authors.affiliation: Molecular Bioinformatics Group, Institute of Computer Science, Faculty of Computer Science and Mathematics, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Robert-Mayer-Str. 11-15, 60325 Frankfurt am Main, Germany, Molecular Bioenergetics Group, Medical School, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany, Functional Proteomics, SFB815 core unit, Medical School, Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany and Nijmegen Centre for Mitochondrial Disorders, Radboud University Medical Centre, 6525 GA, Nijmegen, The Netherlands.
authors.forename: Stefan
authors.initials: S
authors.lastname: Dröse
authors.affiliation: Molecular Bioinformatics Group, Institute of Computer Science, Faculty of Computer Science and Mathematics, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Robert-Mayer-Str. 11-15, 60325 Frankfurt am Main, Germany, Molecular Bioenergetics Group, Medical School, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany, Functional Proteomics, SFB815 core unit, Medical School, Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany and Nijmegen Centre for Mitochondrial Disorders, Radboud University Medical Centre, 6525 GA, Nijmegen, The Netherlands Molecular Bioinformatics Group, Institute of Computer Science, Faculty of Computer Science and Mathematics, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Robert-Mayer-Str. 11-15, 60325 Frankfurt am Main, Germany, Molecular Bioenergetics Group, Medical School, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany, Functional Proteomics, SFB815 core unit, Medical School, Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany and Nijmegen Centre for Mitochondrial Disorders, Radboud University Medical Centre, 6525 GA, Nijmegen, The Netherlands.
authors.forename: Ilka
authors.initials: I
authors.lastname: Wittig
authors.affiliation: Molecular Bioinformatics Group, Institute of Computer Science, Faculty of Computer Science and Mathematics, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Robert-Mayer-Str. 11-15, 60325 Frankfurt am Main, Germany, Molecular Bioenergetics Group, Medical School, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany, Functional Proteomics, SFB815 core unit, Medical School, Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany and Nijmegen Centre for Mitochondrial Disorders, Radboud University Medical Centre, 6525 GA, Nijmegen, The Netherlands Molecular Bioinformatics Group, Institute of Computer Science, Faculty of Computer Science and Mathematics, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Robert-Mayer-Str. 11-15, 60325 Frankfurt am Main, Germany, Molecular Bioenergetics Group, Medical School, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany, Functional Proteomics, SFB815 core unit, Medical School, Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany and Nijmegen Centre for Mitochondrial Disorders, Radboud University Medical Centre, 6525 GA, Nijmegen, The Netherlands.
authors.forename: Ulrich
authors.initials: U
authors.lastname: Brandt
authors.affiliation: Molecular Bioinformatics Group, Institute of Computer Science, Faculty of Computer Science and Mathematics, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Robert-Mayer-Str. 11-15, 60325 Frankfurt am Main, Germany, Molecular Bioenergetics Group, Medical School, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany, Functional Proteomics, SFB815 core unit, Medical School, Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany and Nijmegen Centre for Mitochondrial Disorders, Radboud University Medical Centre, 6525 GA, Nijmegen, The Netherlands.
authors.forename: Ina
authors.initials: I
authors.lastname: Koch
mesh_terms: D016000:Cluster Analysis; D020869:Gene Expression Profiling; D006801:Humans; D010363:Pattern Recognition, Automated; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software