title: Trends in the diagnosis and management of TTP: European perspective.
abstract: Thrombotic thrombocytopenic purpura diagnosis and therapy has transformed with improved understanding of the disorder and availability of therapies. Plasma exchange remains the cornerstone of treatment. Prompt therapy can improves morbidity and mortality. However, given the plasma volumes used, those offering protection against transfer of microbes are preferable. Reviewed is a brief history of TTP and current plasmas available, their use and safety profiles, concentrating on the current UK recommendations.
authors.affiliation: Department of Haematology, UCLH, 60 Whitfield Street, London WC1, UK. Electronic address: m.scully@ucl.ac.uk.
authors.forename: Marie
authors.initials: M
authors.lastname: Scully
mesh_terms: D006801:Humans; D010951:Plasma Exchange; D011697:Purpura, Thrombotic Thrombocytopenic / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D006113:United Kingdom
keywords: ADAMTS 13; TTP; plasma therapy; viral inactivation