title: A retrospective 3- to 5-year study of the reconstruction of oral function using implant-supported prostheses in patients with hypohidrotic ectodermal dysplasia.
abstract: The aim of this study was to evaluate oral function rehabilitation in patients with hypohidrotic ectodermal dysplasia (HED) using implant-supported prostheses based on bone augmentation. From September 2005 and March 2009, 25 HED patients were chosen for clinical data analysis in this study. The criteria for patient selection included the following: the display of clinical features of HED, the number of congenitally missing teeth (>5), the patient age (>16 years), the patient's willingness, and the patient's tolerance for bone graft surgery and implant placement. Follow-up evaluations were initiated from the time of implant prosthetic placement and scheduled annually for 3-5 years. The effects of oral function reconstruction were assessed based on the cumulative survival and success rates of implants, the health of the peri-implant area, and the degree of patient satisfaction. Twenty-five HED patients received 169 conventional implants and 10 zygomatic implants (179 total implants). During 3-5 years of post-loading evaluations, 5 of the 179 implants failed and 3 implants were removed. The 3-year success and cumulative survival rates were 97.2% and 98.3%, respectively. Furthermore, periodontal probing and radiographic assessments showed that the 3-year incidence of peri-implantitis was 4.5%. Finally, HED patients expressed high degrees of satisfaction with their facial contours, masticatory function, pronunciation ability, and comfort with the implant-supported prostheses. The results of this 3- to 5-year retrospective study indicate that the oral function of HED patients can be effectively reconstructed using bone augmentation and implant-supported prostheses; however, longer term results are warranted in the future.
authors.affiliation: 1  Department of Oral and Craniofacial Implant, Ninth People's Hospital Affiliated with Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
authors.forename: Duohong
authors.initials: D
authors.lastname: Zou
authors.forename: Yiqun
authors.initials: Y
authors.lastname: Wu
authors.forename: Xu Dong
authors.initials: XD
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Huang
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Zhang
authors.forename: Zhiyuan
authors.initials: Z
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000540:Alveolar Ridge Augmentation / Q000379:methods; D000848:Anodontia / Q000534:rehabilitation; D018786:Bone Substitutes / Q000627:therapeutic use; D016025:Bone Transplantation / Q000379:methods; D003758:Dental Implantation, Endosseous / Q000379:methods; D015921:Dental Implants; D019094:Dental Prosthesis, Implant-Supported; D019232:Dental Restoration Failure; D020878:Device Removal; D053358:Ectodermal Dysplasia 1, Anhidrotic / Q000150:complications* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008409:Mastication / Q000502:physiology; D009065:Mouth Rehabilitation / Q000379:methods*; D019857:Osteogenesis, Distraction / Q000379:methods; D017060:Patient Satisfaction; D057873:Peri-Implantitis / Q000209:etiology; D010512:Periodontal Index; D012189:Retrospective Studies; D013060:Speech / Q000502:physiology; D016019:Survival Analysis; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D018786:Bone Substitutes; D015921:Dental Implants
keywords: dental implant; hypodontia; hypohidrotic ectodermal dysplasia; implant-supported prosthesis; oral function construction; peri-implantitis