title: Juvenile xanthogranuloma: unusual intraoral finding.
abstract: Juvenile xanthogranuloma is a rare non-Langerhans cell histiocytosis that usually presents as a self-limiting dermatological condition in young children. Rarely, extracutaneous sites may also be involved. We report a case in a 3-year-old girl that presented intraorally as a solitary, well-defined, soft, purple palatal swelling. Patients with these rare intraoral lesions may present to dentists and subsequently to oral and maxillofacial surgeons. Diagnosis requires histopathological analysis and immunohistochemical staining. Further investigation from other specialties is required to rule out involvement of other organ systems.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Sunderland Royal Hospital, Kayll Road, Sunderland SR4 7TP, United Kingdom. Electronic address: collins.laurence@yahoo.co.uk.
authors.forename: L
authors.initials: L
authors.lastname: Collins
authors.affiliation: Department of Oral and Maxillofacial Surgery, Sunderland Royal Hospital, Kayll Road, Sunderland SR4 7TP, United Kingdom.
authors.forename: R
authors.initials: R
authors.lastname: Banks
authors.affiliation: Centre for Oral Health Research, Newcastle University, Framlington Place, Newcastle Upon Tyne NE2 4BW, United Kingdom.
authors.forename: M
authors.initials: M
authors.lastname: Robinson
mesh_terms: D015703:Antigens, CD / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D015726:Giant Cells / Q000473:pathology; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D008264:Macrophages / Q000473:pathology; D009059:Mouth Diseases / Q000175:diagnosis* / Q000473:pathology; D009078:Mucocele / Q000175:diagnosis; D010159:Palate / Q000473:pathology*; D011127:Polyps / Q000175:diagnosis; D014972:Xanthogranuloma, Juvenile / Q000175:diagnosis* / Q000473:pathology; D000097382:CD68 Molecule
chemical_list: D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; C067980:CD68 antigen, human; D000097382:CD68 Molecule
keywords: Intraoral; Non-Langerhans cell histiocytosis; Palatal swelling; Xanthogranuloma