title: New ZnO nanostructures as non-enzymatic glucose biosensors.
abstract: In a new approach, shape controlled synthesis of zinc oxide nanostructures were carried out using a solvothermal route assisted amino acids such as L-Lysine (lysine), L-Cysteine (cysteine) and L-Arginine (arginine) as bifunctional species with (or without) urea or oxalic acid as additives which affect the pH of the reaction. Rod, powder, particle, cube, rock candy-like, sheet, sphere, brain-like, groundnut-like and pussy willow-like morphologies were obtained through the synthetic route. Particle sizes varied from 25 nm to4 μm. To test the application, nine ZnO nanostructures, formulated by multi-walled carbon nanotube (MWCNT) on glassy carbon electrode (GCE) were applied as new nanobiosensors for detecting glucose in a simple and inexpensive way without using any glucose oxidase or nafion. Glucose sensing accomplished in a phosphate buffer solution (PBS, pH=7) for ZnO/MWCNT/GCE samples. Results showed that in this non-enzymatic biosensor system, spherical ZnO obtained from zinc acetate/cycteine/oxalic acid synthetic route has the highest sensitivity of 64.29 μA/cm(2) mM with repeatable results. For the mentioned sensor, no interference observed in the presence of dopamine, uric acid and fructose.
authors.affiliation: Chemistry & Chemical Engineering Research Center of Iran (CCERCI), Pazhouhesh Blvd., 17th Km. of Tehran- Karaj Highway, Tehran, Iran. Electronic address: Tarlani@ccerci.ac.ir.
authors.forename: Aliakbar
authors.initials: A
authors.lastname: Tarlani
authors.affiliation: Chemistry & Chemical Engineering Research Center of Iran (CCERCI), Pazhouhesh Blvd., 17th Km. of Tehran- Karaj Highway, Tehran, Iran.
authors.forename: Mahtab
authors.initials: M
authors.lastname: Fallah
authors.affiliation: Chemistry & Chemical Engineering Research Center of Iran (CCERCI), Pazhouhesh Blvd., 17th Km. of Tehran- Karaj Highway, Tehran, Iran.
authors.forename: Behzad
authors.initials: B
authors.lastname: Lotfi
authors.affiliation: Chemistry & Chemical Engineering Research Center of Iran (CCERCI), Pazhouhesh Blvd., 17th Km. of Tehran- Karaj Highway, Tehran, Iran.
authors.forename: Avideh
authors.initials: A
authors.lastname: Khazraei
authors.affiliation: Chemistry & Chemical Engineering Research Center of Iran (CCERCI), Pazhouhesh Blvd., 17th Km. of Tehran- Karaj Highway, Tehran, Iran.
authors.forename: Sommayeh
authors.initials: S
authors.lastname: Golsanamlou
authors.affiliation: Institut de Chimie Moléculaire de Reims, CNRS-Université de Reims Champagne-Ardenne, BP 1039 51687, Reims cedex 2, France.
authors.forename: Jacques
authors.initials: J
authors.lastname: Muzart
authors.affiliation: Chemistry & Chemical Engineering Research Center of Iran (CCERCI), Pazhouhesh Blvd., 17th Km. of Tehran- Karaj Highway, Tehran, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Mirza-Aghayan
mesh_terms: D001120:Arginine / Q000737:chemistry; D015374:Biosensing Techniques; D003545:Cysteine / Q000737:chemistry; D055664:Electrochemical Techniques; D004800:Enzymes, Immobilized / Q000737:chemistry; D005947:Glucose / Q000737:chemistry / Q000302:isolation & purification*; D005949:Glucose Oxidase / Q000737:chemistry*; D006801:Humans; D049329:Nanostructures / Q000737:chemistry; D037742:Nanotubes, Carbon / Q000737:chemistry*; D015034:Zinc Oxide / Q000737:chemistry
chemical_list: D004800:Enzymes, Immobilized; D037742:Nanotubes, Carbon; D001120:Arginine; D005949:Glucose Oxidase; D005947:Glucose; D003545:Cysteine; D015034:Zinc Oxide
keywords: Amino acid; Glucose; Nanobiosensor; Non-enzymatic; Solvothermal; Zinc oxide