title: [Gadolinium-based contrast agents for magnetic resonance imaging].
abstract: Gadolinium-based contrast agents are increasingly being used in magnetic resonance imaging. These agents can improve the contrast in images and provide information about function and metabolism, increasing both sensitivity and specificity. We describe the gadolinium-based contrast agents that have been approved for clinical use, detailing their main characteristics based on their chemical structure, stability, and safety. In general terms, these compounds are safe. Nevertheless, adverse reactions, the possibility of nephrotoxicity from these compounds, and the possibility of developing nephrogenic systemic fibrosis will be covered in this article. Lastly, the article will discuss the current guidelines, recommendations, and contraindications for their clinical use, including the management of pregnant and breast-feeding patients.
authors.affiliation: Servicio de Radiodiagnóstico, Hospital General Universitario Gregorio Marañón, Madrid, España.
authors.forename: S
authors.initials: S
authors.lastname: Carrasco Muñoz
authors.affiliation: Servicio de Radiodiagnóstico, Hospital General Universitario Gregorio Marañón, Madrid, España.
authors.forename: C
authors.initials: C
authors.lastname: Calles Blanco
authors.affiliation: Servicio de Radiodiagnóstico, Hospital General Universitario Gregorio Marañón, Madrid, España.
authors.forename: Javier
authors.initials: J
authors.lastname: Marcin
authors.affiliation: Servicio de Radiodiagnóstico, Hospital General Universitario Gregorio Marañón, Madrid, España.
authors.forename: C
authors.initials: C
authors.lastname: Fernández Álvarez
authors.affiliation: Servicio de Radiodiagnóstico, Hospital General Universitario Gregorio Marañón, Madrid, España. Electronic address: javier.lafuente@salud.madrid.org.
authors.forename: J
authors.initials: J
authors.lastname: Lafuente Martínez
mesh_terms: D003287:Contrast Media / Q000009:adverse effects; D005682:Gadolinium; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced / Q000517:prevention & control; D008279:Magnetic Resonance Imaging / Q000379:methods; D054989:Nephrogenic Fibrosing Dermopathy / Q000139:chemically induced / Q000517:prevention & control; D012307:Risk Factors
chemical_list: D003287:Contrast Media; D005682:Gadolinium
keywords: Contrastes; Contrasts; Gadolinio; Gadolinium; Magnetic resonance imaging; Resonancia magnética