title: Kruidenier et al. reply.
authors.affiliation: Epinova DPU, Immuno-Inflammation Therapy Area, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: Laurens
authors.initials: L
authors.lastname: Kruidenier
authors.affiliation: Platform Technology and Science, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: Chun-wa
authors.initials: CW
authors.lastname: Chung
authors.affiliation: Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA.
authors.forename: Zhongjun
authors.initials: Z
authors.lastname: Cheng
authors.affiliation: Epinova DPU, Immuno-Inflammation Therapy Area, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: John
authors.initials: J
authors.lastname: Liddle
authors.affiliation: 1] Structural Genomics Consortium, University of Oxford, Old Road Campus, Roosevelt Drive, Headington OX3 7DQ, UK [2] Botnar Research Centre, NIHR Biomedical Research Unit, University of Oxford OX3 7LD, UK.
authors.forename: KaHing
authors.initials: K
authors.lastname: Che
authors.affiliation: Cellzome AG, Meyerhofstrasse 1, 69117 Heidelberg, Germany.
authors.forename: Gerard
authors.initials: G
authors.lastname: Joberty
authors.affiliation: Cellzome AG, Meyerhofstrasse 1, 69117 Heidelberg, Germany.
authors.forename: Marcus
authors.initials: M
authors.lastname: Bantscheff
authors.affiliation: Structural Genomics Consortium, University of Oxford, Old Road Campus, Roosevelt Drive, Headington OX3 7DQ, UK.
authors.forename: Chas
authors.initials: C
authors.lastname: Bountra
authors.affiliation: Platform Technology and Science, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: Angela
authors.initials: A
authors.lastname: Bridges
authors.affiliation: Epinova DPU, Immuno-Inflammation Therapy Area, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: Hawa
authors.initials: H
authors.lastname: Diallo
authors.affiliation: Cellzome AG, Meyerhofstrasse 1, 69117 Heidelberg, Germany.
authors.forename: Dirk
authors.initials: D
authors.lastname: Eberhard
authors.affiliation: Platform Technology and Science, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: Sue
authors.initials: S
authors.lastname: Hutchinson
authors.affiliation: Platform Technology and Science, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: Emma
authors.initials: E
authors.lastname: Jones
authors.affiliation: Platform Technology and Science, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: Roy
authors.initials: R
authors.lastname: Katso
authors.affiliation: Platform Technology and Science, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: Melanie
authors.initials: M
authors.lastname: Leveridge
authors.affiliation: Epinova DPU, Immuno-Inflammation Therapy Area, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: Palwinder K
authors.initials: PK
authors.lastname: Mander
authors.affiliation: Platform Technology and Science, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: Julie
authors.initials: J
authors.lastname: Mosley
authors.affiliation: Epinova DPU, Immuno-Inflammation Therapy Area, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: Cesar
authors.initials: C
authors.lastname: Ramirez-Molina
authors.affiliation: Platform Technology and Science, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: Paul
authors.initials: P
authors.lastname: Rowland
authors.affiliation: Structural Genomics Consortium, University of Oxford, Old Road Campus, Roosevelt Drive, Headington OX3 7DQ, UK.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Schofield
authors.affiliation: Epinova DPU, Immuno-Inflammation Therapy Area, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Sheppard
authors.affiliation: Epinova DPU, Immuno-Inflammation Therapy Area, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: Julia E
authors.initials: JE
authors.lastname: Smith
authors.affiliation: Botnar Research Centre, NIHR Biomedical Research Unit, University of Oxford OX3 7LD, UK.
authors.forename: Catherine
authors.initials: C
authors.lastname: Swales
authors.affiliation: Platform Technology and Science, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: Robert
authors.initials: R
authors.lastname: Tanner
authors.affiliation: Platform Technology and Science, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: Pamela
authors.initials: P
authors.lastname: Thomas
authors.affiliation: Structural Genomics Consortium, University of Oxford, Old Road Campus, Roosevelt Drive, Headington OX3 7DQ, UK.
authors.forename: Anthony
authors.initials: A
authors.lastname: Tumber
authors.affiliation: Cellzome AG, Meyerhofstrasse 1, 69117 Heidelberg, Germany.
authors.forename: Gerard
authors.initials: G
authors.lastname: Drewes
authors.affiliation: 1] Structural Genomics Consortium, University of Oxford, Old Road Campus, Roosevelt Drive, Headington OX3 7DQ, UK [2] Botnar Research Centre, NIHR Biomedical Research Unit, University of Oxford OX3 7LD, UK.
authors.forename: Udo
authors.initials: U
authors.lastname: Oppermann
authors.affiliation: Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA.
authors.forename: Dinshaw J
authors.initials: DJ
authors.lastname: Patel
authors.affiliation: 1] Epinova DPU, Immuno-Inflammation Therapy Area, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK [2] Pfizer, Biotherapeutics R&D, 200 Cambridgepark Drive, Cambridge, Massachusetts 02140, USA.
authors.forename: Kevin
authors.initials: K
authors.lastname: Lee
authors.affiliation: Epinova DPU, Immuno-Inflammation Therapy Area, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.
authors.forename: David M
authors.initials: DM
authors.lastname: Wilson
mesh_terms: D000818:Animals; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006801:Humans; D056484:Jumonji Domain-Containing Histone Demethylases / Q000037:antagonists & inhibitors*; D008264:Macrophages / Q000187:drug effects* / Q000276:immunology*
chemical_list: D004791:Enzyme Inhibitors; D056484:Jumonji Domain-Containing Histone Demethylases