title: [Evaluation of systemic involving of the connective tissue in children with different localisation of isolated abnormal chords of the left ventricle (ACLV)].
abstract: Evaluation of the systemic involving of the connective tissue (SICT) under the new Ghent nosology (2010) showed that in children with isolated ACLV born to parents exposed to the Chernobyl disaster, its expression is associated with their location and quantity. The degree of systemic involvement of connective tissue is confirmed by the results of the analysis of features echostructure of isolated ACLV (the presence of thickening and calcification), echomorphometry, assessment of systolic (hypokinetic organization of the central hemodynamics), and the relaxation functions of the heart (initiation of diastolic dysfunction). High level of SICT (score greater than 5) indicates systemic damage to the body and particularly the heart, which requires dynamic monitoring and preventive measures. Found that the diagnostic and monitoring of children with isolated ACLV may be based on registration of systemic involvement of connective tissue with the calculation of points under the new Ghent nosology of 2010.
authors.forename: V H
authors.initials: VH
authors.lastname: Kondrashova
authors.forename: L P
authors.initials: LP
authors.lastname: Sheĭko
authors.forename: N S
authors.initials: NS
authors.lastname: Kondrashova
mesh_terms: D000328:Adult; D002114:Calcinosis / Q000175:diagnosis / Q000473:pathology* / Q000503:physiopathology; D009202:Cardiomyopathies / Q000175:diagnosis / Q000473:pathology* / Q000503:physiopathology; D047852:Chernobyl Nuclear Accident; D002648:Child; D002675:Child, Preschool; D003238:Connective Tissue / Q000473:pathology* / Q000503:physiopathology; D003971:Diastole; D005260:Female; D006352:Heart Ventricles / Q000473:pathology / Q000503:physiopathology; D006439:Hemodynamics; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000175:diagnosis / Q000473:pathology* / Q000503:physiopathology; D012720:Severity of Illness Index; D013599:Systole