title: Susac's syndrome: the value of fundus fluorescein angiography.
abstract: A 19-year-old woman presented with a 4-week history of headache, ataxia, vertigo, confusion, intermittent blurred vision in the right eye and intermittent hearing loss. MRI revealed white matter lesions and 'pepper pot' lesions of the corpus callosum. The cerebrospinal fluid had raised protein and lymphocytes. Fundal examination revealed multiple peripheral arterial occlusions in the both eyes confirmed with fundus fluorescein angiography (FFA). A diagnosis of Susac's syndrome was made. The patient was initially treated with steroids, followed by azathioprine and intravenous immunoglobulins (IVIg). Clinical improvement was noted, associated with improvement of the retinal circulation on FFA.
authors.affiliation: Department of Ophthalmology, University Hospital Coventry, Coventry, UK.
authors.forename: Imran Joseph
authors.initials: IJ
authors.lastname: Khan
authors.affiliation: Department of Neurology, University Hospital Coventry, Coventry, UK.
authors.forename: Holger
authors.initials: H
authors.lastname: Allroggen
authors.affiliation: Department of Ophthalmology, University Hospital Coventry, Coventry, UK.
authors.forename: Sergio
authors.initials: S
authors.lastname: Pagliarini
mesh_terms: D001921:Brain / Q000473:pathology*; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008279:Magnetic Resonance Imaging; D015356:Retinal Artery Occlusion / Q000175:diagnosis* / Q000209:etiology; D055955:Susac Syndrome / Q000150:complications / Q000175:diagnosis*; D055815:Young Adult