title: California Breast Cancer Prevention Initiatives: Setting a research agenda for prevention.
abstract: The environment is an underutilized pathway to breast cancer prevention. Current research approaches and funding streams related to breast cancer and the environment are unequal to the task at hand. We undertook the California Breast Cancer Prevention Initiatives, a four-year comprehensive effort to set a research agenda related to breast cancer, the environment, disparities and prevention. We identified 20 topics for Concept Proposals reflecting a life-course approach and the complex etiology of breast cancer; considering the environment as chemical, physical and socially constructed exposures that are experienced concurrently: at home, in the community and at work; and addressing how we should be modifying the world around us to promote a less carcinogenic environment. Redirecting breast cancer research toward prevention-oriented discovery could significantly reduce the incidence and associated disparities of the disease among future generations.
authors.affiliation: University of California, San Francisco, Program on Reproductive Health and the Environment, 1330 Broadway, Suite 1135, Oakland, CA 94612, USA. Electronic address: suttonp@obgyn.ucsf.edu.
authors.forename: P
authors.initials: P
authors.lastname: Sutton
authors.affiliation: California Breast Cancer Research Program, University of California, Office of the President, 300 Lakeside Drive, 6th Floor, Oakland, CA 94612-3550, USA.
authors.forename: M H E
authors.initials: MH
authors.lastname: Kavanaugh-Lynch
authors.affiliation: Plumbline Consulting and Coaching, 541 South 52nd Street, Omaha, NE 68106, USA.
authors.forename: M
authors.initials: M
authors.lastname: Plumb
authors.affiliation: University of California, San Francisco, 3333 California Street, San Francisco, CA 94143, USA.
authors.forename: I H
authors.initials: IH
authors.lastname: Yen
authors.affiliation: Commonweal, P.O. Box 316, Bolinas, CA 94924, USA.
authors.forename: H
authors.initials: H
authors.lastname: Sarantis
authors.affiliation: California Breast Cancer Research Program, University of California, Office of the President, 300 Lakeside Drive, 6th Floor, Oakland, CA 94612-3550, USA.
authors.forename: C L
authors.initials: CL
authors.lastname: Thomsen
authors.affiliation: California Breast Cancer Research Program, University of California, Office of the President, 300 Lakeside Drive, 6th Floor, Oakland, CA 94612-3550, USA.
authors.forename: S
authors.initials: S
authors.lastname: Campleman
authors.affiliation: Plumbline Consulting and Coaching, 541 South 52nd Street, Omaha, NE 68106, USA.
authors.forename: E
authors.initials: E
authors.lastname: Galpern
authors.affiliation: University of California, San Francisco, Program on Reproductive Health and the Environment, 1330 Broadway, Suite 1135, Oakland, CA 94612, USA.
authors.forename: C
authors.initials: C
authors.lastname: Dickenson
authors.affiliation: University of California, San Francisco, Program on Reproductive Health and the Environment, 1330 Broadway, Suite 1135, Oakland, CA 94612, USA.
authors.forename: T J
authors.initials: TJ
authors.lastname: Woodruff
mesh_terms: D001943:Breast Neoplasms / Q000139:chemically induced / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control*; D002140:California; D002274:Carcinogens, Environmental / Q000009:adverse effects*; D002471:Cell Transformation, Neoplastic / Q000139:chemically induced / Q000378:metabolism / Q000473:pathology*; D003299:Cooperative Behavior; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D054624:Health Status Disparities; D054625:Healthcare Disparities; D006801:Humans; D033183:Interdisciplinary Communication; D008019:Life Style; D042361:Mammary Glands, Human / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D011247:Pregnancy; D016730:Program Development; D012107:Research Design; D018570:Risk Assessment; D012307:Risk Factors; D040242:Risk Reduction Behavior; D015398:Signal Transduction / Q000187:drug effects
chemical_list: D002274:Carcinogens, Environmental
keywords: Breast cancer; Disparities; Environment; Environmental chemicals; Prevention