title: Characterizing self-reported sleep disturbance after mild traumatic brain injury.
abstract: Sleep disturbance after mild traumatic brain injury (mTBI) is commonly reported as debilitating and persistent. However, the nature of this disturbance is poorly understood. This study sought to characterize sleep after mTBI compared with a control group. A cross-sectional matched case control design was used. Thirty-three persons with recent mTBI (1-6 months ago) and 33 age, sex, and ethnicity matched controls completed established questionnaires of sleep quality, quantity, timing, and sleep-related daytime impairment. The mTBI participants were compared with an independent sample of close-matched controls (CMCs; n = 33) to allow partial internal replication. Compared with controls, persons with mTBI reported significantly greater sleep disturbance, more severe insomnia symptoms, a longer duration of wake after sleep onset, and greater sleep-related impairment (all medium to large effects, Cohen's d > 0.5). No differences were found in sleep quantity, timing, sleep onset latency, sleep efficiency, or daytime sleepiness. All findings except a measure of sleep timing (i.e., sleep midpoint) were replicated for CMCs. These results indicate a difference in the magnitude and nature of perceived sleep disturbance after mTBI compared with controls, where persons with mTBI report poorer sleep quality and greater sleep-related impairment. Sleep quantity and timing did not differ between the groups. These preliminary findings should guide the provision of clearer advice to patients about the aspects of their sleep that may change after mTBI and could inform treatment selection.
authors.affiliation: 1 Clinical Neuropsychology Research Group, School of Psychology and Counselling, Queensland University of Technology , Brisbane, Australia .
authors.forename: Karen A
authors.initials: KA
authors.lastname: Sullivan
authors.forename: Shannon L
authors.initials: SL
authors.lastname: Edmed
authors.forename: Alicia C
authors.initials: AC
authors.lastname: Allan
authors.forename: Lina J E
authors.initials: LJ
authors.lastname: Karlsson
authors.forename: Simon S
authors.initials: SS
authors.lastname: Smith
mesh_terms: D000293:Adolescent; D000328:Adult; D001930:Brain Injuries / Q000150:complications*; D003430:Cross-Sectional Studies; D059026:Diagnostic Self Evaluation; D005260:Female; D006801:Humans; D008297:Male; D038223:Post-Concussion Syndrome / Q000175:diagnosis* / Q000209:etiology; D012890:Sleep; D012893:Sleep Wake Disorders / Q000175:diagnosis* / Q000209:etiology; D011795:Surveys and Questionnaires; D055815:Young Adult
keywords: concussion; excessive daytime sleepiness; insomnia; post-concussion syndrome