title: Pd-catalyzed intramolecular aerobic oxidative C-H amination of 2-aryl-3-(arylamino)quinazolinones: synthesis of fluorescent indazolo[3,2-b]quinazolinones.
abstract: A palladium-catalyzed intramolecular aerobic oxidative C-H amination of 2-aryl-3-(arylamino)quinazolinones has been developed, providing a variety of substituted indazolo[3,2-b]quinazolinone derivatives in moderate to excellent yields. Preliminary mechanistic studies suggested that a palladacycle dimer could be the key intermediate, which underwent a cascade "rollover" cyclometalation and C-H amination sequence. Furthermore, the potential utility of these products has been demonstrated as a new class of blue fluorophores for fluorescent materials.
authors.affiliation: College of Chemistry & Materials Engineering, Wenzhou University , Wenzhou, Zhejiang 325035, P. R. China.
authors.forename: Weiguang
authors.initials: W
authors.lastname: Yang
authors.forename: Jiuxi
authors.initials: J
authors.lastname: Chen
authors.forename: Xiaobo
authors.initials: X
authors.lastname: Huang
authors.forename: Jinchang
authors.initials: J
authors.lastname: Ding
authors.forename: Miaochang
authors.initials: M
authors.lastname: Liu
authors.forename: Huayue
authors.initials: H
authors.lastname: Wu