title: Cell-surface molecules involved in T-cell functions.
abstract: A complete understanding of immune response mechanisms requires both identification of the cellular subpopulations participating in a given response and elucidation of the antigen-specific receptors employed by these cells. A great deal of recent study has been directed at the characterization of T-cell subpopulations and the receptor structures expressed by these cells. Perhaps the most powerful tools so far employed have been the serological reagents which distinguish cell-surface molecules on lymphoid populations. In this review, Jeffrey Bluestone and Richard Hodes summarize our understanding of the surface molecules expressed on functionally distinct T-cell subpopulations, and the role of these molecules in antigen-specific T-cell activation.
authors.affiliation: Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20205, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Bluestone
authors.forename: R J
authors.initials: RJ
authors.lastname: Hodes