title: [Hemodynamic effects of spinal anaesthesia during caesarian section in pregnant women with hypertensive disorders].
abstract: OBJECTIVE
  To make the comparative analysis of the changes of main parameters of haemodynamic during caesarean section with spinal anaesthesia (SA) in patients with uncomplicated pregnancy and pregnancy with hypertensive disorders.
  
  
  METHODS
  The study included 103 pregnant women undergoing caesarean section under SA. The comparative analysis of the main haemodynamic parameters was performed in patients into three groups: an uncomplicated pregnancy (n = 35); pregnancy with chronic hypertension (n = 33) and pregnancy complicated by severe preeclampsia (n = 35). Heart rate (HR), mean blood pressure (BP), cardiac index (CI) and systemic vascular resistance (SVR) were measured by noninvasive bioimpedans technology. Data were recorded at 5 stages of the study.
  
  
  CONCLUSIONS
  The data of study demonstrated that haemodynamic stability better if SA is used during caesarean section in women with normal pregnancy. In the group of pregnant women with severe preeclampsia observed the most significant hemodynamic changes: BP and SVR decreased significantly greater at all stages of the operation, whereas the increase SI on the 3rd stage was higher in comparison with the control group.
  
  
  CONCLUSIONS
  There were significant differences changes in the main hemodynamic parameters between groups at all stages of the study. Results of this survey suggest that hemodynamic response to anaesthesia depends on the initial state of the circulatory system.
authors.forename: S V
authors.initials: SV
authors.lastname: Kinzhalova
authors.forename: R A
authors.initials: RA
authors.lastname: Makarov
authors.forename: N S
authors.initials: NS
authors.lastname: Davydova
mesh_terms: D000328:Adult; D000775:Anesthesia, Spinal; D001794:Blood Pressure / Q000502:physiology; D002585:Cesarean Section / Q000379:methods*; D002908:Chronic Disease; D005260:Female; D005865:Gestational Age; D006339:Heart Rate / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D011225:Pre-Eclampsia / Q000503:physiopathology*; D011247:Pregnancy; D014655:Vascular Resistance / Q000502:physiology