title: [Diabetes and hearing impairment due to mitochondrial mutation].
abstract: Mutations in the mitochondrial genome can cause mitochondrial diabetes. We present two cases in which the same mutation, mtDNA3243A>G, caused two different phenotypes: maternally inherited diabetes and deafness and mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes. Mitochondrial disease can imitate a variety of common con-ditions and should be considered in the case of multisystem disease, complex neurological symptoms or neurological symptoms combined with symptoms of other organ systems.
authors.affiliation: Skarøvænget 10, 6000 Kolding. jens-jacob.lauterlein2@rsyd.dk.
authors.forename: Jens-Jacob
authors.initials: JJ
authors.lastname: Lauterlein
authors.forename: Inger
authors.initials: I
authors.lastname: Olsen
authors.forename: Knud
authors.initials: K
authors.lastname: Yderstræde
authors.forename: Morten Frost
authors.initials: MF
authors.lastname: Nielsen
mesh_terms: D004272:DNA, Mitochondrial / Q000235:genetics*; D003638:Deafness / Q000150:complications / Q000235:genetics*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D017241:MELAS Syndrome / Q000150:complications / Q000235:genetics*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D055815:Young Adult
chemical_list: D004272:DNA, Mitochondrial