title: Auditory symptoms as an unrecognized manifestation of opioid toxicity: two case reports.
abstract: Neuropsychiatric and gastrointestinal side effects of opioids are well documented, but self-reported hearing disturbance from opioids is often unrecognized. Two cases are presented illustrating a possible association between auditory symptoms and opioid toxicity. Possible mechanisms are discussed.
authors.forename: Alison
authors.initials: A
authors.lastname: Cran
authors.forename: Fiona
authors.initials: F
authors.lastname: Kiely
authors.forename: Tony
authors.initials: T
authors.lastname: O'Brien
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000009:adverse effects*; D003692:Delayed-Action Preparations / Q000009:adverse effects; D005260:Female; D006311:Hearing Disorders / Q000139:chemically induced*; D006801:Humans; D004091:Hydromorphone / Q000008:administration & dosage / Q000009:adverse effects*; D055104:Infusions, Subcutaneous / Q000009:adverse effects; D008875:Middle Aged
chemical_list: D000701:Analgesics, Opioid; D003692:Delayed-Action Preparations; D004091:Hydromorphone
keywords: auditory symptoms; hearing disturbance; opioid; toxicity