title: The prevention and treatment of postpartum haemorrhage: what do we know, and where do we go to next?
abstract: Postpartum haemorrhage (PPH) remains a major cause of maternal deaths worldwide, and is estimated to cause the death of a woman every 10 minutes. This review presents the latest clinical advice, including new evidence on controlled cord traction, misoprostol, and oxytocin. The controversy around the diagnosis of PPH, the limitations of universal prophylaxis, and novel ways to provide obstetric first aid are also presented. It ends with a call to develop high-quality front-line obstetric services that can deal rapidly with unexpected haemorrhages as well as minimising blood loss at critical times: major abruption, placenta praevia, and caesarean for prolonged labour.
authors.affiliation: Sanyu Research Unit, Department of Women's and Children's Health, Liverpool Women's Hospital, University of Liverpool, Liverpool, UK.
authors.forename: A
authors.initials: A
authors.lastname: Weeks
mesh_terms: D001803:Blood Transfusion; D058128:Compression Bandages; D003695:Delivery of Health Care; D005260:Female; D006700:Home Childbirth; D006801:Humans; D007749:Labor Stage, Third; D010120:Oxytocics / Q000627:therapeutic use*; D006473:Postpartum Hemorrhage / Q000517:prevention & control / Q000628:therapy*; D011247:Pregnancy
chemical_list: D010120:Oxytocics
keywords: Maternal mortality; misoprostol; oxytocin; postpartum haemorrhage