title: 99mTc-MDP SPECT/CT demonstrating extraosseous periarticular amyloid deposits in primary systemic amyloidosis associated with multiple myeloma.
abstract: Amyloidosis is a rare disorder characterized by variable extracellular accumulation of a complex substance consisting of proteinaceous fibrils (amyloid fibrils) and nonfibrillar glycoprotein or amyloid P component. We present a case of a primary systemic amyloidosis associated with multiple myeloma in a 48-year-old woman whose Tc-MDP SPECT/CT study revealed extraosseous periarticular uptake in amyloid deposits with no abnormal focal tracer uptake in the bone.
authors.affiliation: From the Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Krishan Kant
authors.initials: KK
authors.lastname: Agarwal
authors.forename: Sellam
authors.initials: S
authors.lastname: Karunanithi
authors.forename: Shambo Guha
authors.initials: SG
authors.lastname: Roy
authors.forename: Chandrasekhar
authors.initials: C
authors.lastname: Bal
authors.forename: Rakesh
authors.initials: R
authors.lastname: Kumar
mesh_terms: D000686:Amyloidosis / Q000150:complications / Q000000981:diagnostic imaging*; D001842:Bone and Bones / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D000075363:Immunoglobulin Light-chain Amyloidosis; D008875:Middle Aged; D064847:Multimodal Imaging; D009101:Multiple Myeloma / Q000150:complications / Q000000981:diagnostic imaging*; D058225:Plaque, Amyloid / Q000150:complications / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate