title: Standardized uptake values highly correlate with tumor size and Fuhrman grade in patients with clear cell renal cell carcinoma.
abstract: BACKGROUND
  We investigated the correlation between standardized uptake value (SUVmax), tumor size and Fuhrman grade in patients with renal cell carcinoma (RC).
  
  
  METHODS
  We retrospectively analyzed the data of 54 patients with clear cell renal cell carcinoma histopathologically diagnosed who underwent fluorine-18 fluoro-2 deoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) between January 2005 and March 2014.
  
  
  RESULTS
  Avarage tumor sizes were 5.64±1.85, 6.85±2.24 and 7.98±2.45 in low, medium and high SUVmax groups, respectively. The Spearman's correlation coefficient between the tumor size and SUVmax was 0.385 (p=0.004) and between the Fuhrman grade and SUVmax was 0.578 (p<0.001).
  
  
  CONCLUSIONS
  SUVmax appears highly correlated with tumor size and Fuhrman grade in patients with histopathologically confirmed clear cell RC. Multicenter studies are needed to provide larger series for more accurate results.
authors.affiliation: Faculty of Medicine, Istanbul Medipol University, Istanbul, Turkey E-mail dremrecan@hotmail.com.
authors.forename: Emre Can
authors.initials: EC
authors.lastname: Polat
authors.forename: Alper
authors.initials: A
authors.lastname: Otunctemur
authors.forename: Emin
authors.initials: E
authors.lastname: Ozbek
authors.forename: Huseyin
authors.initials: H
authors.lastname: Besiroglu
authors.forename: Murat
authors.initials: M
authors.lastname: Dursun
authors.forename: Kutan
authors.initials: K
authors.lastname: Ozer
authors.forename: Mustafa Ozan
authors.initials: MO
authors.lastname: Horsanali
mesh_terms: D000328:Adult; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000473:pathology*; D005260:Female; D019788:Fluorodeoxyglucose F18; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging / Q000592:standards*; D060787:Neoplasm Grading; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D011379:Prognosis; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D047368:Tumor Burden
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18