title: Genome editing: a tool for research and therapy: towards a functional understanding of variants for molecular diagnostics using genome editing.
authors.affiliation: Department of Pathology, Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
authors.forename: Shengdar Q
authors.initials: SQ
authors.lastname: Tsai
authors.affiliation: Department of Pathology, Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
authors.forename: A John
authors.initials: AJ
authors.lastname: Iafrate
authors.affiliation: Department of Pathology, Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
authors.forename: J Keith
authors.initials: JK
authors.lastname: Joung
mesh_terms: D000818:Animals; D064113:CRISPR-Cas Systems; D004351:Drug Resistance / Q000235:genetics; D014644:Genetic Variation; D015894:Genome, Human; D006801:Humans; D051379:Mice; D009154:Mutation; D057089:Pathology, Molecular / Q000379:methods*; D017393:RNA Editing; D057170:Translational Research, Biomedical