title: ["I am a little out of breath". When a commonplace symptom hides a rare disease: cardiac amyloidosis].
abstract: Based on a case report, this article reviews the different forms of cardiac involvement in amyloidosis. This affection refers to the extracellular tissue deposition of protein fibrils (the amyloid substance), which gradually invades a variety of organs, disrupting their function. The clinical presentation depends on the type of the amyloidogenic protein and on its main distribution. The most severe cardiac impairment and with the worse prognosis is seen in its primary form (or AL), while it is less frequent, with a slower course and a better prognosis in its other forms: secondary (AA), familial (ATTR) or senile (SSA).
authors.forename: Sophie
authors.initials: S
authors.lastname: Excoffier
authors.forename: Hakan
authors.initials: H
authors.lastname: Celik
authors.forename: Sophie
authors.initials: S
authors.lastname: Durieux-Paillard
mesh_terms: D000686:Amyloidosis / Q000145:classification / Q000175:diagnosis* / Q000628:therapy*; D001706:Biopsy; D017147:Defibrillators, Implantable; D004417:Dyspnea / Q000209:etiology; D004452:Echocardiography; D004562:Electrocardiography; D006331:Heart Diseases / Q000175:diagnosis* / Q000628:therapy*; D016027:Heart Transplantation; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D020097:Natriuretic Peptide, Brain / Q000097:blood; D010446:Peptide Fragments / Q000097:blood
chemical_list: D010446:Peptide Fragments; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain