title: Eosinophilic cystitis: three cases, and a review over 10 years.
abstract: Eosinophilic cystitis (EC) is a rare disease. We describe three cases, where presentations of the disease are similar. To highlight probable causes of the disease, symptoms, clinical findings and treatment modalities, we reviewed 56 cases over a 10-year period. The most common symptoms were frequency, dysuria, urgency, pain and haematuria. Common clinical findings were presence of bladder mass, peripheral eosinophilia and thickened bladder wall. A variety of medical treatments were used, most frequently steroids, antibiotics and antihistamines. Recurrence occurred in patients on tapering or discontinuing prednisone, among other reasons. There is no consensus about the treatment of EC, but In light of our findings in this review, the treatment of choice in our department will be tapered prednisone over 6-8 weeks in combination with antihistamine.
authors.affiliation: Urological Department, Roskilde Hospital, Roskilde, Denmark.
authors.forename: Karina Sif Søndergaard
authors.initials: KS
authors.lastname: Mosholt
authors.affiliation: Urological Department, Roskilde Hospital, Roskilde, Denmark.
authors.forename: Claus
authors.initials: C
authors.lastname: Dahl
authors.affiliation: Urological Department, Roskilde Hospital, Roskilde, Denmark.
authors.forename: Nessn Htum
authors.initials: NH
authors.lastname: Azawi
mesh_terms: D000293:Adolescent; D000368:Aged; D000369:Aged, 80 and over; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003556:Cystitis / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D006633:Histamine Antagonists / Q000627:therapeutic use; D006801:Humans; D008297:Male; D010146:Pain / Q000209:etiology; D011241:Prednisone / Q000627:therapeutic use; D014555:Urination Disorders / Q000209:etiology
chemical_list: D000893:Anti-Inflammatory Agents; D006633:Histamine Antagonists; D011241:Prednisone