title: Rare Association of Myeloid leukaemia of Down Syndrome with Granulocytic Sarcoma.
abstract: We report an 18-months old boy with trisomy 21 who initially presented with myelodysplastic syndrome MDS, and later transformed into acute megakaryoblastic leukaemia AML. At presentation he was found to have some unusual findings namely multiple soft tissue masses over scalp, left elbow and over the knee joints as well as hard mass felt in left hip. Biopsy of soft tissue of scalp revealed granulocytic sarcoma. Generally granulocytic sarcoma is seen with AML-M2 and its association with AML-M7, to our belief has rarely been reported previously.
authors.affiliation: Dr Mohammad Adil Obaid, Department of Haematology, NBK Children's Cancer Hospital, Al-Sabah Hospital, Kuwait. Phone No. +965 97726590. Email: dradilobaid@gmail.com, dradilobaid@rediffmail.com.
authors.forename: M A
authors.initials: MA
authors.lastname: Obaid
authors.affiliation: Department of Haematology, NBK Children's Cancer Hospital, Al-Sabah Hospital, Kuwait.
authors.forename: M
authors.initials: M
authors.lastname: Bourusly
authors.affiliation: Great Ormond Street Hospital, London.
authors.forename: P
authors.initials: P
authors.lastname: Ancliff
authors.affiliation: Department of Haematology, NBK Children's Cancer Hospital, Al-Sabah Hospital, Kuwait.
authors.forename: E
authors.initials: E
authors.lastname: Al Matter