title: Replication of NTNG1 association in schizophrenia.
abstract: This is a case-control study of the association of NTNG1 subtypes with schizophrenia among a group of individuals from a Caucasian population. Netrins including NTNG1 are known to be axon guidance factors in the developing brain. They could be very important contributors to the genetic risk for psychosis. We examined the hypothesis that NTNG1 allelic variation contributes to the risk for schizophrenia. Our group was able to replicate the findings of Zhu and colleagues among Han Chinese individuals. This is the first finding of this association in a North American population.
authors.affiliation: Department of Psychiatry, University of Arizona, Tucson, Arizona, USA.
authors.forename: James A
authors.initials: JA
authors.lastname: Wilcox
authors.forename: Syed
authors.initials: S
authors.lastname: Quadri
mesh_terms: D001483:Base Sequence; D016022:Case-Control Studies; D017931:DNA Primers; D058851:GPI-Linked Proteins / Q000235:genetics; D006801:Humans; D009419:Nerve Tissue Proteins / Q000235:genetics*; D000075385:Netrins; D020641:Polymorphism, Single Nucleotide; D012559:Schizophrenia / Q000235:genetics*
chemical_list: D017931:DNA Primers; D058851:GPI-Linked Proteins; C463082:NTNG1 protein, human; D009419:Nerve Tissue Proteins; D000075385:Netrins