title: Liver enzymes and psychological well-being response to aerobic exercise training in patients with chronic hepatitis C.
abstract: BACKGROUND
  Chronic hepatitis C (CHC) is a medical condition that has broad implications for a person's physical and psychological health.
  
  
  OBJECTIVE
  The aim of this study was to detect changes in liver enzymes and psychological well-being in response to aerobic exercise training in patients with CHC.
  
  
  METHODS
  Fifty CHC patients were included in two equal groups. The first group (A) received aerobic exercise training in addition to their regular medical treatment. The second group (B) received no training and only has their regular medical treatment. The program consisted of three sessions per week for three months.
  
  
  RESULTS
  There was a significant decrease in mean values of Alkaline Phosphatase (ALP), Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST), Gamma - Glutamyltransferase (GGT), Beck Depression Inventory (BDI ) & Profile of Mood States(POMS) and increase in Rosenberg Self-Esteem Scale (RSES) in group (A) after treatments, but the changes in group (B) were not significant. Also, there were significant differences between mean levels of the investigated parameters in group (A) and group (B) at the end of the study.
  
  
  CONCLUSIONS
  Aerobic exercise training improves hepatic enzymes and psychological well-being in patients with chronic hepatitis C.
authors.affiliation: Department of Physical Therapy, Faculty of Applied Medical Sciences, King Abdulaziz University.
authors.forename: Shehab M
authors.initials: SM
authors.lastname: Abd El-Kader
authors.affiliation: Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University.
authors.forename: Osama H
authors.initials: OH
authors.lastname: Al-Jiffri
authors.affiliation: Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University.
authors.forename: Fadwa M
authors.initials: FM
authors.lastname: Al-Shreef
mesh_terms: D000328:Adult; D000410:Alanine Transaminase / Q000097:blood*; D001219:Aspartate Aminotransferases / Q000097:blood*; D015992:Body Mass Index; D005081:Exercise Therapy / Q000379:methods* / Q000523:psychology; D005260:Female; D019698:Hepatitis C, Chronic / Q000097:blood / Q000150:complications / Q000523:psychology* / Q000628:therapy*; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D011569:Psychiatric Status Rating Scales; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D005723:gamma-Glutamyltransferase / Q000097:blood*
chemical_list: D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
keywords: aerobic exercise; chronic hepatitis C; liver enzymes; psychological well-being