title: Crystal structure of 2-[(E)-4-benz-yloxy-2-hy-droxy-benzyl-idene]-N-cyclo-hexyl-hydrazinecarbo-thio-amide aceto-nitrile hemisolvate.
abstract: The asymmetric unit of the title compound, C21H25N3O2S·0.5C2H3N, contains two independent mol-ecules with almost similar structural properties along with a solvent mol-ecule of aceto-nitrile. The compound exists in the E conformation with respect to the azomethine C=N double bond. The hydrazinecarbo-thio-amide moieties in both independent mol-ecules are almost planar [maximum deviations of 0.013 (2) and 0.007 (2) Å]. The mol-ecular conformation is stabilized in each case by an intra-molecular N-H⋯N hydrogen bond. In the crystal, pairs of N-H⋯S hydrogen bonds link each of the independent mol-ecules into inversion dimers. The dimers are inter-connected by means of three C-H⋯π inter-actions.
authors.affiliation: Department of Applied Chemistry, Cochin University of Science and Technology, Kochi 682 022, India.
authors.forename: N R
authors.initials: NR
authors.lastname: Sajitha
authors.affiliation: Department of Chemistry, Faculty of Science, Eastern University, Sri Lanka, Chenkalady, Sri Lanka.
authors.forename: M
authors.initials: M
authors.lastname: Sithambaresan
authors.affiliation: Department of Applied Chemistry, Cochin University of Science and Technology, Kochi 682 022, India.
authors.forename: M R Prathapachandra
authors.initials: MR
authors.lastname: Kurup
keywords: C—H⋯π inter­actions; anti­microbial applications; crystal structure; hydrazinecarbo­thio­amide; hydrogen bonding