title: Separation of planar rotamers through intramolecular hydrogen bonding in polysubstituted 5-nitrosopyrimidines.
abstract: While purifying new polysubstituted 5-nitrosopyrimidines, the unique separation of pairs of rotamers as chemical species, stabilized by a single intramolecular hydrogen bond and differing only in nitroso group orientation, was achieved. This interesting stereochemical phenomenon is compared to the well-known atropisomerism.
authors.affiliation: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i., Flemingovo nám. 2, CZ-166 10 Prague 6, Czech Republic. janeba@uochb.cas.cz dracinsky@uochb.cas.cz.
authors.forename: L
authors.initials: L
authors.lastname: Čechová
authors.forename: E
authors.initials: E
authors.lastname: Procházková
authors.forename: I
authors.initials: I
authors.lastname: Císařová
authors.forename: M
authors.initials: M
authors.lastname: Dračínský
authors.forename: Z
authors.initials: Z
authors.lastname: Janeba
mesh_terms: D006860:Hydrogen Bonding; D009603:Nitroso Compounds / Q000737:chemistry*; D011743:Pyrimidines / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D009603:Nitroso Compounds; D011743:Pyrimidines