title: Novel use of endoscopically placed fiducial markers for targeted radiation therapy of colonic lymphomas.
abstract: Non-Hodgkin's lymphomas (NHL) are an important variety of gastrointestinal tumors with increasing incidence and prevalence. Traditional management of NHL with chemotherapy is challenging and expanding evidence points to significant tumor response to radiation therapy (RT). However, there exists a wide range of radiation-related toxicities. Optimization of exact tumor marking coupled with minimization of the radius of radiation delivery is essential to increase patient's tolerance and decrease side effects of the treatment. We report our experience with mantle cell lymphoma of the colon treated with precision RT after endoscopic placement of resolution clips in a "shooting target" fashion in a patient who failed conventional chemotherapy. Fourteen months after completion of RT, the patient remains in complete remission.
authors.affiliation: Division of Gastroenterology (Grigoriy E. Gurvits), New York University School of Medicine, Langone Medical Center, New York, USA.
authors.forename: Grigoriy E
authors.initials: GE
authors.lastname: Gurvits
authors.affiliation: Department of Medicine (Joseph Marsano), New York University School of Medicine, Langone Medical Center, New York, USA.
authors.forename: Joseph
authors.initials: J
authors.lastname: Marsano
authors.affiliation: Department of Hematology and Oncology (Boris Kobrinsky), New York University School of Medicine, Langone Medical Center, New York, USA.
authors.forename: Boris
authors.initials: B
authors.lastname: Kobrinsky
authors.affiliation: Department of Radiation Oncology (Samuel Shin, Nicholas Sanfilippo), New York University School of Medicine, Langone Medical Center, New York, USA.
authors.forename: Samuel
authors.initials: S
authors.lastname: Shin
authors.affiliation: Department of Radiation Oncology (Samuel Shin, Nicholas Sanfilippo), New York University School of Medicine, Langone Medical Center, New York, USA.
authors.forename: Nicholas
authors.initials: N
authors.lastname: Sanfilippo
authors.affiliation: Department of Anesthesiology (Dimitri Volkov), New York University School of Medicine, Langone Medical Center, New York, USA.
authors.forename: Dmitri
authors.initials: D
authors.lastname: Volkov
keywords: Endoscopy; colonoscopy; gastrointestinal cancer; mantle cell lymphoma; radiation therapy