title: Consensus statement with recommendations on active surveillance inclusion criteria and definition of progression in men with localized prostate cancer: the critical role of the pathologist.
abstract: Active surveillance (AS) is an important management option for men with low-risk, clinically localized prostate cancer. The clinical parameters for patient selection and definition of progression for AS protocols are evolving as data from several large cohorts matures. Vital to this process is the critical role pathologic parameters play in identifying appropriate candidates for AS. These findings need to be reproducible and consistently reported by surgical pathologists. This report highlights the importance of accurate pathology reporting as a critical component of these protocols.
authors.affiliation: Section of Pathological Anatomy, School of Medicine, United Hospitals, Polytechnic University of the Marche Region, Via Conca 71, Torrette, 60126, Ancona, Italy, r.montironi@univpm.it.
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Montironi
authors.forename: Elizabeth H
authors.initials: EH
authors.lastname: Hammond
authors.forename: Daniel W
authors.initials: DW
authors.lastname: Lin
authors.forename: John L
authors.initials: JL
authors.lastname: Gore
authors.forename: John R
authors.initials: JR
authors.lastname: Srigley
authors.forename: Hema
authors.initials: H
authors.lastname: Samaratunga
authors.forename: Lars
authors.initials: L
authors.lastname: Egevad
authors.forename: Mark A
authors.initials: MA
authors.lastname: Rubin
authors.forename: John
authors.initials: J
authors.lastname: Nacey
authors.forename: Laurence
authors.initials: L
authors.lastname: Klotz
authors.forename: Howard
authors.initials: H
authors.lastname: Sandler
authors.forename: Anthony L
authors.initials: AL
authors.lastname: Zietman
authors.forename: Stuart
authors.initials: S
authors.lastname: Holden
authors.forename: Peter A
authors.initials: PA
authors.lastname: Humphrey
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Evans
authors.forename: Brett
authors.initials: B
authors.lastname: Delahunt
authors.forename: Jesse K
authors.initials: JK
authors.lastname: McKenney
authors.forename: Daniel
authors.initials: D
authors.lastname: Berney
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Wheeler
authors.forename: Arul
authors.initials: A
authors.lastname: Chinnaiyan
authors.forename: Lawrence
authors.initials: L
authors.lastname: True
authors.forename: Beatrice
authors.initials: B
authors.lastname: Knudsen
authors.forename: Jonathan I
authors.initials: JI
authors.lastname: Epstein
authors.forename: Mahul B
authors.initials: MB
authors.lastname: Amin
mesh_terms: D018450:Disease Progression; D006801:Humans; D008297:Male; D010338:Pathology, Clinical / Q000592:standards*; D018579:Patient Selection; D011471:Prostatic Neoplasms / Q000473:pathology*; D057832:Watchful Waiting