title: Chemical composition, antioxidant activity and antibacterial effect of essential oil of the aerial parts of Salvia sclareoides.
abstract: OBJECTIVE
  To determine the chemical composition, antioxidant activity and antibacterial properties of essential oils of the aerial parts of Salvia sclareoides (S. sclareoides).
  
  
  METHODS
  The essential oil of the areal parts of S. sclareoides was obtained by using hydrodistillation method and the composition of the volatile components analyzed by gas chromatography method coupled with mass spectrometry detector. The antimicrobial capacity of the essential oil of S. sclareoides was investigated by microdilution technique. The antioxidant activities were determined employing inhibition of 2,2-diphenyl-1-picrylhydrazyl hydrate radical method.
  
  
  RESULTS
  Mass spectra were searched against mass spectrometry databases and sixty components were recognized. Non-terpenoids (41.6%) and sesquiterpenes (39.7%) were determined as the main components of the essential oil. The main identified components were, linalool (27.6%), trans-caryophyllene (16.6%), beta.-trans-ocimene (11.831%), germacrene-D (10%), bicyclogermacrene (3.3%) and caryophyllene oxide (2.8%). Two monoterpens (13.2%) and three oxygenated sesquiterpenes (5.5%) were also obtained from the essential oil of the S. sclareoides
  
  
  CONCLUSIONS
  Results indicated that essential oil of S. sclareoides includes rather higher proportions of non-terpenoid and sesquiterpenes compounds with good antioxidant and antibacterial properties.
authors.affiliation: Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Sepahvand
authors.affiliation: Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
authors.forename: Bahram
authors.initials: B
authors.lastname: Delfan
authors.affiliation: Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Iran.
authors.forename: Saeed
authors.initials: S
authors.lastname: Ghanbarzadeh
authors.affiliation: Young Researchers and Elite Club, Khorramabad Branch, Islamic Azad University, Khorramabad, Iran.
authors.forename: Marzieh
authors.initials: M
authors.lastname: Rashidipour
authors.affiliation: Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
authors.forename: Gholam Hassan
authors.initials: GH
authors.lastname: Veiskarami
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Iran. Electronic address: Jvd.ghasemian@gmail.com.
authors.forename: Javad
authors.initials: J
authors.lastname: Ghasemian-Yadegari
keywords: Antimicrobial capacity; Antioxidative property; Essential oil; Salvia sclareoides