title: Spontaneous regression of a clinically-advanced histologically low-grade follicular lymphoma involving the breast: case report and review of the literature.
abstract: A 68-year-old woman was diagnosed as having grade 1 follicular lymphoma of the left breast in November 2012. Bone marrow infiltration was noted histologically and confirmed by Southern blot analysis of the IgHJH locus. The clinical stage was IVA, advanced stage. According to the Follicular Lymphoma International Prognostic Index, the patient was classified into the high risk group. The general condition was good and there were no organ symptoms, therefore, the patient was kept under observation without treatment. After one year and 2 months of follow up, The mass was regressed spontaneously. As previous studies have suggested a poor prognosis of patients with an advanced clinical stage of the disease, careful follow-up of our patient is necessary.
authors.affiliation: Department of Hematology, Juntendo University Urayasu Hospital, 1-1, 2-chome, Tomioka, Urayasu, Chiba Prefecture 279-0021 Japan.
authors.forename: Yasunobu
authors.initials: Y
authors.lastname: Sekiguchi
authors.affiliation: Department of Hematology, Juntendo University Urayasu Hospital, 1-1, 2-chome, Tomioka, Urayasu, Chiba Prefecture 279-0021 Japan ; Department of Hematology, Juntendo University Hospital, 3-1-3 Hongo, Bunkyo-ku, Tokyo, 113-8431 Japan.
authors.forename: Asami
authors.initials: A
authors.lastname: Shimada
authors.affiliation: Shibanishi Clinic, Shimada-Setsubi Building 1F, 27-16, 2-chome, Shibanishi, Kawaguchi, Saitama Prefecture 333-0855 Japan.
authors.forename: Hidenori
authors.initials: H
authors.lastname: Imai
authors.affiliation: Department of Hematology, Juntendo University Urayasu Hospital, 1-1, 2-chome, Tomioka, Urayasu, Chiba Prefecture 279-0021 Japan.
authors.forename: Mutsumi
authors.initials: M
authors.lastname: Wakabayashi
authors.affiliation: Department of Hematology, Juntendo University Urayasu Hospital, 1-1, 2-chome, Tomioka, Urayasu, Chiba Prefecture 279-0021 Japan.
authors.forename: Keiji
authors.initials: K
authors.lastname: Sugimoto
authors.affiliation: Department of Laboratory Medicine, Juntendo University, Urayasu Hospital, 1-1 2-chome, Tomioka, Urayasu, Chiba Prefecture 279-0021 Japan.
authors.forename: Noriko
authors.initials: N
authors.lastname: Nakamura
authors.affiliation: Department of Laboratory Medicine, Juntendo University, Urayasu Hospital, 1-1 2-chome, Tomioka, Urayasu, Chiba Prefecture 279-0021 Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Sawada
authors.affiliation: Department of Hematology, Juntendo University Hospital, 3-1-3 Hongo, Bunkyo-ku, Tokyo, 113-8431 Japan.
authors.forename: Norio
authors.initials: N
authors.lastname: Komatsu
authors.affiliation: Department of Hematology, Juntendo University Urayasu Hospital, 1-1, 2-chome, Tomioka, Urayasu, Chiba Prefecture 279-0021 Japan.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Noguchi
keywords: Breast; Follicular lymphoma; Primary; Secondary