title: Signal decomposition for X-ray dark-field imaging.
abstract: Grating-based X-ray dark-field imaging is a new imaging modality. It allows the visualization of structures at micrometer scale due to small-angle scattering of the X-ray beam. However, reading darkfield images is challenging as absorption and edge-diffraction effects also contribute to the dark-field signal, without adding diagnostic value. In this paper, we present a novel--and to our knowledge the first--algorithm for isolating small-angle scattering in dark-field images, which greatly improves their interpretability. To this end, our algorithm utilizes the information available from the absorption and differential phase images to identify clinically irrelevant contributions to the dark-field image. Experimental results on phantom and ex-vivo breast data promise a greatly enhanced diagnostic value of dark-field images.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Kaeppler
authors.forename: Florian
authors.initials: F
authors.lastname: Bayer
authors.forename: Thomas
authors.initials: T
authors.lastname: Weber
authors.forename: Andreas
authors.initials: A
authors.lastname: Maier
authors.forename: Gisela
authors.initials: G
authors.lastname: Anton
authors.forename: Joachim
authors.initials: J
authors.lastname: Hornegger
authors.forename: Matthias
authors.initials: M
authors.lastname: Beckmann
authors.forename: Peter A
authors.initials: PA
authors.lastname: Fasching
authors.forename: Arndt
authors.initials: A
authors.lastname: Hartmann
authors.forename: Felix
authors.initials: F
authors.lastname: Heindl
authors.forename: Thilo
authors.initials: T
authors.lastname: Michel
authors.forename: Gueluemser
authors.initials: G
authors.lastname: Oezguel
authors.forename: Georg
authors.initials: G
authors.lastname: Pelzer
authors.forename: Claudia
authors.initials: C
authors.lastname: Rauh
authors.forename: Jens
authors.initials: J
authors.lastname: Rieger
authors.forename: Ruediger
authors.initials: R
authors.lastname: Schulz-Wendtland
authors.forename: Michael
authors.initials: M
authors.lastname: Uder
authors.forename: David
authors.initials: D
authors.lastname: Wachter
authors.forename: Evelyn
authors.initials: E
authors.lastname: Wenkel
authors.forename: Christian
authors.initials: C
authors.lastname: Riess
mesh_terms: D000465:Algorithms; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008327:Mammography / Q000379:methods*; D011856:Radiographic Image Enhancement / Q000379:methods*; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D053838:Scattering, Small Angle; D012680:Sensitivity and Specificity; D014961:X-Ray Diffraction / Q000379:methods*