title: Synthetic studies towards Zetekitoxin AB: preparation of 4,5-epi-11-hydroxy-saxitoxinol.
abstract: A concise synthesis of 4,5-epi-11-hydroxy-saxitoxinol utilizing D-ribose to direct an asymmetric Mannich reaction. This approach allows many modes of reactivity, which can be used to access various analogs of saxitoxin.
authors.affiliation: Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA.
authors.forename: Aaron D
authors.initials: AD
authors.lastname: Pearson
authors.affiliation: Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA.
authors.forename: Robert M
authors.initials: RM
authors.lastname: Williams
keywords: Diamino acid; Mannich reaction; Saxitoxin; Sodium channel; Zetekitoxin AB