title: Liver disease after hematopoietic cell transplantation in adults.
abstract: Liver-related complications constitute a large component of the overall morbidity and mortality associated with hematopoietic cell transplantation. Affecting up to 80% of allogeneic HCT recipients, prompt recognition and treatment are essential. The differential diagnosis is broad and is best categorized by time of onset after transplantation. Early complications include drug-induced liver injury, sinusoidal obstruction syndrome, and graft-versus-host disease. Late complications include infectious sequelae, cirrhosis, and hepatic malignancies. Patients being considered for hematopoietic cell transplantation should be screened and evaluated for liver-related complications to help improve outcomes.
authors.affiliation: Department of Medicine, Division of Digestive Diseases, Emory Transplant Center, Emory University, Atlanta, GA, USA. Electronic address: jpnorvell@emory.edu.
authors.forename: J P
authors.initials: JP
authors.lastname: Norvell
mesh_terms: D000328:Adult; D006086:Graft vs Host Disease / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D012307:Risk Factors