title: Surface-Enhanced Raman Spectroscopy Sensors From Nanobiosilica With Self-Assembled Plasmonic Nanoparticles.
abstract: We present an innovative surface-enhanced Raman spectroscopy (SERS) sensor based on a biological-plasmonic hybrid nanostructure by self-assembling silver (Ag) nanoparticles into diatom frustules. The photonic-crystal-like diatom frustules provide a spatially confined electric field with enhanced intensity that can form hybrid photonic-plasmonic modes through the optical coupling with Ag nanoparticles. The experimental results demonstrate 4-6×and 9-12×improvement of sensitivities to detect the Raman dye for resonance and nonresonance SERS sensing, respectively. Such low-cost and high-sensitivity SERS sensors have significant potentials for label-free biosensing.
authors.affiliation: Oregon State University Corvallis, OR 97331 USA.
authors.forename: Fanghui
authors.initials: F
authors.lastname: Ren
authors.affiliation: School of Chemical, Biological, and Environmental Engineering Oregon State University Corvallis, OR 97331 USA.
authors.forename: Jeremy
authors.initials: J
authors.lastname: Campbell
authors.affiliation: School of Chemical, Biological, and Environmental Engineering Oregon State University Corvallis, OR 97331 USA.
authors.forename: Gregory L
authors.initials: GL
authors.lastname: Rorrer
authors.affiliation: Department of Electrical Engineering and Computer Science, Oregon State University, OR 97331 USA.
authors.forename: Alan X
authors.initials: AX
authors.lastname: Wang
keywords: Diatom frustules; photonic crystals; surface plasmons; surface-enhanced Raman spectroscopy