title: Sensitive detection of transcription factors using an Ag(+)-stabilized self-assembly triplex DNA molecular switch.
abstract: Based on a Ag(+)-stabilized self-assembly triplex DNA molecular switch (Ag(+)-STDMS), a simple, enzyme-free and sensitive new fluorescent strategy for detection of transcription factors was developed, achieving high sensitivity towards purified targets and real biological samples.
authors.affiliation: Key Laboratory for Colloid and Interface Chemistry of Education Ministry, Department of Chemistry, Shandong University, Jinan, 250100, China. wjiang@sdu.edu.cn.
authors.forename: Desong
authors.initials: D
authors.lastname: Zhu
authors.forename: Jing
authors.initials: J
authors.lastname: Zhu
authors.forename: Ye
authors.initials: Y
authors.lastname: Zhu
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Jiang
mesh_terms: D000476:Alkanesulfonates / Q000737:chemistry; D001391:Azo Compounds / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D052002:NF-kappa B p50 Subunit / Q000032:analysis* / Q000737:chemistry; D012834:Silver / Q000737:chemistry*; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology
chemical_list: D000476:Alkanesulfonates; D001391:Azo Compounds; C000598590:BHQ-1 compound; D005456:Fluorescent Dyes; D052002:NF-kappa B p50 Subunit; D014409:Tumor Necrosis Factor-alpha; C051802:triplex DNA; D012834:Silver; D004247:DNA