title: Aptamer-mediated 'turn-off/turn-on' nanozyme activity of gold nanoparticles for kanamycin detection.
abstract: A new ultrafast and highly sensitive 'turn-off/turn-on' biosensing approach that combines the intrinsic peroxidase-like activity of gold nanoparticles (GNPs) with the high affinity and specificity of a ssDNA aptamer is presented for the efficient detection of a model small molecule kanamycin.
authors.affiliation: Ian Potter NanoBioSensing Facility, NanoBiotechnology Research Laboratory, School of Applied Science, RMIT University, GPO Box 2476V, Melbourne VIC 3001, Australia. vipul.bansal@rmit.edu.au.
authors.forename: Tarun Kumar
authors.initials: TK
authors.lastname: Sharma
authors.forename: Rajesh
authors.initials: R
authors.lastname: Ramanathan
authors.forename: Pabudi
authors.initials: P
authors.lastname: Weerathunge
authors.forename: Mahsa
authors.initials: M
authors.lastname: Mohammadtaheri
authors.forename: Hemant Kumar
authors.initials: HK
authors.lastname: Daima
authors.forename: Ravi
authors.initials: R
authors.lastname: Shukla
authors.forename: Vipul
authors.initials: V
authors.lastname: Bansal
mesh_terms: D052157:Aptamers, Nucleotide / Q000737:chemistry*; D015374:Biosensing Techniques; D004277:DNA, Single-Stranded / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D007612:Kanamycin / Q000032:analysis*; D053768:Metal Nanoparticles / Q000737:chemistry*; D009195:Peroxidase / Q000737:chemistry / Q000378:metabolism
chemical_list: D052157:Aptamers, Nucleotide; D004277:DNA, Single-Stranded; D007612:Kanamycin; D006046:Gold; D009195:Peroxidase