title: miRseqViewer: multi-panel visualization of sequence, structure and expression for analysis of microRNA sequencing data.
abstract: CONCLUSIONS
  Deep sequencing of small RNAs has become a routine process in recent years, but no dedicated viewer is as yet available to explore the sequence features simultaneously along with secondary structure and gene expression of microRNA (miRNA). We present a highly interactive application that visualizes the sequence alignment, secondary structure and normalized read counts in synchronous multipanel windows. This helps users to easily examine the relationships between the structure of precursor and the sequences and abundance of final products and thereby will facilitate the studies on miRNA biogenesis and regulation. The project manager handles multiple samples of multiple groups. The read alignment is imported in BAM file format. Implemented features comprise sorting, zooming, highlighting, editing, filtering, saving, exporting, etc. Currently, miRseqViewer supports 84 organisms whose annotation is available at miRBase.
  
  
  METHODS
  miRseqViewer, implemented in Java, is available at https://github.com/insoo078/mirseqviewer or at http://msv.kobic.re.kr.
  
  
  BACKGROUND
  sanghyuk@ewha.ac.kr.
authors.affiliation: Korean Bioinformation Center (KOBIC), KRIBB, Daejeon 305-806, Korea, School of Biological Sciences, Seoul National University, Seoul 151-742, Korea and Department of Life Science and Ewha Research Center for Systems Biology (ERCSB), Ewha Womans University, Seoul 120-750, Korea.
authors.forename: Insu
authors.initials: I
authors.lastname: Jang
authors.affiliation: Korean Bioinformation Center (KOBIC), KRIBB, Daejeon 305-806, Korea, School of Biological Sciences, Seoul National University, Seoul 151-742, Korea and Department of Life Science and Ewha Research Center for Systems Biology (ERCSB), Ewha Womans University, Seoul 120-750, Korea.
authors.forename: Hyeshik
authors.initials: H
authors.lastname: Chang
authors.affiliation: Korean Bioinformation Center (KOBIC), KRIBB, Daejeon 305-806, Korea, School of Biological Sciences, Seoul National University, Seoul 151-742, Korea and Department of Life Science and Ewha Research Center for Systems Biology (ERCSB), Ewha Womans University, Seoul 120-750, Korea.
authors.forename: Yukyung
authors.initials: Y
authors.lastname: Jun
authors.affiliation: Korean Bioinformation Center (KOBIC), KRIBB, Daejeon 305-806, Korea, School of Biological Sciences, Seoul National University, Seoul 151-742, Korea and Department of Life Science and Ewha Research Center for Systems Biology (ERCSB), Ewha Womans University, Seoul 120-750, Korea.
authors.forename: Seongjin
authors.initials: S
authors.lastname: Park
authors.affiliation: Korean Bioinformation Center (KOBIC), KRIBB, Daejeon 305-806, Korea, School of Biological Sciences, Seoul National University, Seoul 151-742, Korea and Department of Life Science and Ewha Research Center for Systems Biology (ERCSB), Ewha Womans University, Seoul 120-750, Korea.
authors.forename: Jin Ok
authors.initials: JO
authors.lastname: Yang
authors.affiliation: Korean Bioinformation Center (KOBIC), KRIBB, Daejeon 305-806, Korea, School of Biological Sciences, Seoul National University, Seoul 151-742, Korea and Department of Life Science and Ewha Research Center for Systems Biology (ERCSB), Ewha Womans University, Seoul 120-750, Korea.
authors.forename: Byungwook
authors.initials: B
authors.lastname: Lee
authors.affiliation: Korean Bioinformation Center (KOBIC), KRIBB, Daejeon 305-806, Korea, School of Biological Sciences, Seoul National University, Seoul 151-742, Korea and Department of Life Science and Ewha Research Center for Systems Biology (ERCSB), Ewha Womans University, Seoul 120-750, Korea.
authors.forename: Wankyu
authors.initials: W
authors.lastname: Kim
authors.affiliation: Korean Bioinformation Center (KOBIC), KRIBB, Daejeon 305-806, Korea, School of Biological Sciences, Seoul National University, Seoul 151-742, Korea and Department of Life Science and Ewha Research Center for Systems Biology (ERCSB), Ewha Womans University, Seoul 120-750, Korea.
authors.forename: V Narry
authors.initials: VN
authors.lastname: Kim
authors.affiliation: Korean Bioinformation Center (KOBIC), KRIBB, Daejeon 305-806, Korea, School of Biological Sciences, Seoul National University, Seoul 151-742, Korea and Department of Life Science and Ewha Research Center for Systems Biology (ERCSB), Ewha Womans University, Seoul 120-750, Korea.
authors.forename: Sanghyuk
authors.initials: S
authors.lastname: Lee
mesh_terms: D019295:Computational Biology / Q000379:methods*; D003196:Computer Graphics; D030561:Databases, Nucleic Acid; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D035683:MicroRNAs / Q000235:genetics*; D016415:Sequence Alignment; D017423:Sequence Analysis, RNA / Q000379:methods*; D012984:Software
chemical_list: D035683:MicroRNAs