title: How to conduct clinical research studies using high quality-clinical databases in the critical care.
abstract: The sources of intensive care-related information and the means of communication increase rapidly. We presented here an overview of what should be done to collect high quality database. In a second part, the principle of the choice of the research question, the outcome, the explanatory variables and the statistical methods to address the question are overviewed, emphasizing major and frequent pitfalls which should be avoided.
authors.affiliation: Centro de Coordenação de base de dados OUTCOMEREA, Instituto Albert Bonniot, La Tronche, França.
authors.forename: Adrien
authors.initials: A
authors.lastname: Francais
authors.affiliation: Centro de Coordenação de base de dados OUTCOMEREA, Instituto Albert Bonniot, La Tronche, França.
authors.forename: Aurélien
authors.initials: A
authors.lastname: Vesin
authors.affiliation: Centro de Coordenação de base de dados OUTCOMEREA, Instituto Albert Bonniot, La Tronche, França.
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Timsit