title: [Significant prognostic factors in stage IV gastric cancer].
abstract: The aim of this study was to evaluate clinicopathological variables, including the granulocyte-to-lymphocyte ratio(G/L ratio), as prognostic factors for Stage IV gastric cancer patients. A total of 70 patients treated for Stage IV gastric cancer were enrolled in this study. Univariate analysis indicated that age ≥70 years, performance status >2, resection not being performed, chemotherapy not being administered, high C-reactive protein(CRP)levels, and carbohydrate antigen 19-9 levels were significantly associated with poor survival. Multivariate analysis of these factors identified resection not being performed, chemotherapy not being administered, and high CRP levels as independent unfavorable factors of survival. Although the G/L ratio was not a prognostic factor for Stage IV gastric cancer patients in this study, further studies with greater number of patients are required to determine whether the G/L ratio is a significant biomarker associated with survival.
authors.affiliation: Dept. of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University.
authors.forename: Okihide
authors.initials: O
authors.lastname: Suzuki
authors.forename: Minoru
authors.initials: M
authors.lastname: Fukuchi
authors.forename: Hisashi
authors.initials: H
authors.lastname: Onozawa
authors.forename: Noriyasu
authors.initials: N
authors.lastname: Chika
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hatano
authors.forename: Hideko
authors.initials: H
authors.lastname: Imaizumi
authors.forename: Takeaki
authors.initials: T
authors.lastname: Matsuzawa
authors.forename: Toru
authors.initials: T
authors.lastname: Ishiguro
authors.forename: Koki
authors.initials: K
authors.lastname: Kuwabara
authors.forename: Jun
authors.initials: J
authors.lastname: Sobajima
authors.forename: Takehiko
authors.initials: T
authors.lastname: Sakimoto
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Baba
authors.forename: Youichi
authors.initials: Y
authors.lastname: Kumagai
authors.forename: Keiichiro
authors.initials: K
authors.lastname: Ishibashi
authors.forename: Erito
authors.initials: E
authors.lastname: Mochiki
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Ishida
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000473:pathology* / Q000628:therapy