title: Platelet-rich fibrin in the treatment of periodontal bone defects.
abstract: BACKGROUND
  Periodontitis is characterized by the formation of true pockets, bone loss and attachment loss. Various techniques have been attempted in the past to truly regenerate the lost periodontal structures, albeit with variable outcome. In this evolution, the technique being tried out widely is the use of platelet rich concentrates, namely platelet-rich fibrin (PRF).
  
  
  METHODS
  In this report, we present a case of surgical treatment of osseous bone defects namely two walled crater and dehiscence treated in posterior teeth with autologously prepared platelet rich fibrin mixed with hydroxy apatite bone graft and PRF in the form of a membrane.
  
  
  CONCLUSIONS
  Our results showed clinical improvements in all the clinical parameters postoperatively namely the pocket depth reduction and gain in attachment level and hence, PRF can be used alone or in combination with the bone graft to yield successful clinical results in treating periodontal osseous defects.
  
  
  CONCLUSIONS
  Platelet-rich fibrin is an effective alternative to platelet-rich plasma (PRP) in reconstructing bone defects.
authors.affiliation: Reader, Department of Periodontics, Tagore Dental College, Chennai Tamil Nadu, India, e-mail: vathathmaja@yahoo.co.in.
authors.forename: Aravindhan T
authors.initials: AT
authors.lastname: Ranganathan
authors.affiliation: Professor and Head, Department of Periodontics, Tagore Dental College, Chennai Tamil Nadu, India.
authors.forename: Chitraa R
authors.initials: CR
authors.lastname: Chandran
mesh_terms: D000328:Adult; D016301:Alveolar Bone Loss / Q000601:surgery*; D001792:Blood Platelets / Q000502:physiology*; D001861:Bone Regeneration / Q000502:physiology; D018786:Bone Substitutes / Q000627:therapeutic use; D055113:Chronic Periodontitis / Q000601:surgery; D017886:Durapatite / Q000627:therapeutic use; D005260:Female; D005337:Fibrin / Q000627:therapeutic use*; D005500:Follow-Up Studies; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods*; D006801:Humans; D008567:Membranes, Artificial; D017622:Periodontal Attachment Loss / Q000601:surgery; D010514:Periodontal Pocket / Q000601:surgery; D013524:Surgical Flaps / Q000601:surgery
chemical_list: D018786:Bone Substitutes; D008567:Membranes, Artificial; D005337:Fibrin; D017886:Durapatite