title: [Oxidative stress development in the tissues of salivary glands of rats in conditions of monosodium glutamate-induced obesity].
abstract: Pathogenic mechanisms of damage of salivary glands under obesity are an insufficiently studied problem of modem medicine. On experimental model of obesity induced by monosodium glutamate, free-radical processes and antioxidant defense system were studied in the tissues of salivary glands of rats. Under experimental obesity induced by monosodium glutamate there is a significant increase of the content of thio-barbituric acid reactive substances and a significant decrease in the activity of superoxide dismutase and catalase. Thus, it indicates to the misbalance of prooxidant and antioxidant systems and the development of oxidative stress.
authors.forename: L P
authors.initials: LP
authors.lastname: Hordiienko
authors.forename: T V
authors.initials: TV
authors.lastname: Berehova
authors.forename: K S
authors.initials: KS
authors.lastname: Neporada
authors.forename: T M
authors.initials: TM
authors.lastname: Falalieieva
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D002374:Catalase / Q000378:metabolism; D005260:Female; D005609:Free Radicals / Q000378:metabolism; D008297:Male; D009765:Obesity / Q000139:chemically induced / Q000201:enzymology / Q000378:metabolism*; D018384:Oxidative Stress; D051381:Rats; D012469:Salivary Glands / Q000378:metabolism*; D012970:Sodium Glutamate / Q000494:pharmacology*; D013482:Superoxide Dismutase / Q000378:metabolism; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism
chemical_list: D000975:Antioxidants; D005609:Free Radicals; D017392:Thiobarbituric Acid Reactive Substances; D002374:Catalase; D013482:Superoxide Dismutase; D012970:Sodium Glutamate