title: [Effect of coenzyme Q10 on rat myocardiumin the acute stage of experimental infarction].
abstract: The influence of coenzyme Q10 (CoQ10) on early ischemic deterioration was studied on Wistar rats with experimental myocardial infarction. CoQ10 (30 mg/kg) was injected intravenously 10 min after coronary artery occlusion, and morphometric analysis was performed for 72 h after the onset of ischemia. CoQ10-treated rats had restricted total myocardial damage (by 52%), including areas of necrosis (by 84%) and areas of cellular inflammatory infiltration (by 38%) as compared to saline-treated rats (p < 0.001).
authors.forename: O G
authors.initials: OG
authors.lastname: Tokareva
authors.forename: A V
authors.initials: AV
authors.lastname: Ivanov
authors.forename: N V
authors.initials: NV
authors.lastname: Danilova
authors.forename: E A
authors.initials: EA
authors.lastname: Gorodetskaia
authors.forename: P G
authors.initials: PG
authors.lastname: Mal'kov
authors.forename: N M
authors.initials: NM
authors.lastname: Gaĭfullin
authors.forename: E I
authors.initials: EI
authors.lastname: Kalenikova
authors.forename: O S
authors.initials: OS
authors.lastname: Medvedev
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000378:metabolism* / Q000473:pathology; D009206:Myocardium / Q000378:metabolism* / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar; D014451:Ubiquinone / Q000031:analogs & derivatives* / Q000494:pharmacology; D014815:Vitamins / Q000494:pharmacology*
chemical_list: D014815:Vitamins; D014451:Ubiquinone; C024989:coenzyme Q10