title: Primary intrathymic lymphangioma.
abstract: OBJECTIVE
  Lymphangiomas are relatively uncommon lesions of the lymphatic channels that can arise in virtually any part of the body provided by lymphatic vessels. The most common localization is the head/neck region, with only sporadic reports in other sites. The mediastinum is a rare location, with around 20 cases reported in the literature.
  
  
  METHODS
  We describe one case of mediastinal lymphangioma with a true intrathymic localization, which to our knowledge has never been described.
  
  
  RESULTS
  The gross features and microscopic findings are reported with a discussion of the clinicopathologic signatures of this pathologic entity.
  
  
  CONCLUSIONS
  Intrathymic lymphangioma should always be taken into consideration in the differential diagnosis of cystic mediastinal lesions in children and adult patients.
authors.affiliation: From Department of Pathology, "Santo Spirito" Hospital, Rome, Italy; stefano.licci@hotmail.it.
authors.forename: Stefano
authors.initials: S
authors.lastname: Licci
authors.affiliation: Department of Thoracic Surgery, University of Perugia, Perugia, Italy; and.
authors.forename: Francesco
authors.initials: F
authors.lastname: Puma
authors.affiliation: Institute of Pathologic Anatomy, University of Perugia-"Santa Maria" Hospital, Terni, Italy.
authors.forename: Marta
authors.initials: M
authors.lastname: Sbaraglia
authors.affiliation: Institute of Pathologic Anatomy, University of Perugia-"Santa Maria" Hospital, Terni, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Ascani
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008202:Lymphangioma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D008206:Lymphatic Diseases / Q000175:diagnosis / Q000601:surgery*; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D013950:Thymus Gland / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome
keywords: Cyst; Lymphangioma; Mediastinum; Thymus