title: [Peripheral arterial thromboembolism in patients with non valvular atrial fibrillation: a single center case-control study].
abstract: OBJECTIVE
  To explore the clinical characteristics and risk factors of peripheral arterial thromboembolism (PAT) in patients with non valvular atrial fibrillation (NVAF).
  
  
  METHODS
  A total of 18 456 patients admitted in our hospital and diagnosed with NVAF were included in this study. The study population was divided into three groups [PAT group, cerebral thromboembolism (CT) group and no thromboembolism group]. Risk factors of PAT were assessed by multivariate logistic regression.
  
  
  RESULTS
  The incidence of PAT and CT was 1.1% (204 cases) and 27.8% (5 132 cases), respectively. The in-hospital mortality of PAT group was 11.8% (24/204), in which the in-hospital mortality due to mesenteric arterial thromboembolism (37.5%, 6/16) was the highest. Multivariate logistic regression indicated that vascular disease (OR = 3.9, 95% CI 2.13-7.08, P < 0.01), age ≥ 65 years (OR = 2.7, 95% CI 1.66-4.27, P < 0.01), hypertension (OR = 2.1, 95% CI 1.36-3.34, P < 0.01), history of stroke/TIA/arterial thromboembolism (OR = 2.0, 95% CI 1.26-3.17, P < 0.01) and congestive heart failure (OR = 1.9, 95% CI 1.22-2.86, P < 0.01) were independent risk factors of PAT. Prevalence of vascular disease and histories of PAT was higher in PAT group than in CT group (P < 0.01), while CHADS2 and CHA2DS2VASc scores were similar between the PAT and CT groups.
  
  
  CONCLUSIONS
  PAT is not uncommon in NVAF patients, risk factors for PAT in NVAF patients are vascular disease, advanced age, hypertension, history of stroke/TIA/arterial thromboembolism and congestive heart failure.
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.
authors.forename: Sanshuai
authors.initials: S
authors.lastname: Chang
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.
authors.forename: Dong
authors.initials: D
authors.lastname: Chang
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Qiu
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.
authors.forename: Qiaobing
authors.initials: Q
authors.lastname: Sun
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.
authors.forename: Shulong
authors.initials: S
authors.lastname: Zhang
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.
authors.forename: Yunlong
authors.initials: Y
authors.lastname: Xia
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.
authors.forename: Yanzong
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China. Email: gaoljmd@126.com.
authors.forename: Lianjun
authors.initials: L
authors.lastname: Gao
mesh_terms: D001281:Atrial Fibrillation / Q000150:complications*; D016022:Case-Control Studies; D006333:Heart Failure; D017052:Hospital Mortality; D006760:Hospitalization; D006801:Humans; D006973:Hypertension; D015994:Incidence; D012307:Risk Factors; D020521:Stroke; D013923:Thromboembolism / Q000453:epidemiology / Q000209:etiology*; D014652:Vascular Diseases