title: Bilateral lenticular Encephalitozoon cuniculi infection in a snow leopard (Panthera uncia).
abstract: Bilateral phacoclastic uveitis caused by lenticular infection with Encephalitozoon cuniculi is described in a snow leopard. The diagnosis was made on histopathological and immunohistological examination of both eyes submitted after postmortem examination. There was a positive antibody titer for E. cuniculi (1:320). Polymerase chain reaction (PCR) and sequence analysis of formalin-fixed, paraffin-embedded ocular tissue detected the DNA of E. cuniculi, strain III. No other systemic lesions attributable to the E. cuniculi infection were identified.
authors.affiliation: CytoPath Ltd, PO Box 24, Ledbury, Herefordshire, HR8 2YD, UK.
authors.forename: Emma Jane
authors.initials: EJ
authors.lastname: Scurrell
authors.forename: Ellen
authors.initials: E
authors.lastname: Holding
authors.forename: Jane
authors.initials: J
authors.lastname: Hopper
authors.forename: Daniela
authors.initials: D
authors.lastname: Denk
authors.forename: Andrea
authors.initials: A
authors.lastname: Fuchs-Baumgartinger
authors.forename: Katja
authors.initials: K
authors.lastname: Silbermayr
authors.forename: Barbara
authors.initials: B
authors.lastname: Nell
mesh_terms: D000818:Animals; D009670:Encephalitozoon cuniculi / Q000302:isolation & purification*; D016890:Encephalitozoonosis / Q000662:veterinary*; D015821:Eye Infections, Fungal / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D008297:Male; D046009:Panthera
keywords: Encephalitozoon; eyes; lens; phacoclastic; snow leopard