title: Lewis and Brønsted acid cocatalyzed reductive deoxyallenylation of propargylic alcohols with 2-nitrobenzenesulfonylhydrazide.
abstract: Reductive deoxyallenylation of sterically hindered tertiary propargylic alcohols was realized on reaction with 2-nitrobenzenesulfonylhydrazide (NBSH) by the combined use of Lewis and Brønsted acid catalysts. This method features a broad substrate scope, mild reaction conditions, and good functional-group tolerance, and affords various mono-, di-, and trisubstituted allenes in good-to-excellent yields. The synthetic utility of this method was demonstrated by the synthesis of 2H-chromenes and 1,2-dihydroquinolines.
authors.affiliation: Department of Chemistry, Northeast Normal University, Changchun 130024 (P. R. China).
authors.forename: Zhaohong
authors.initials: Z
authors.lastname: Liu
authors.forename: Peiqiu
authors.initials: P
authors.lastname: Liao
authors.forename: Xihe
authors.initials: X
authors.lastname: Bi
keywords: 2H-chromenes; allenes; deoxyallenylation; propargylic alcohols