title: Reed's syndrome: segmental piloleimyomas type 1 and uterus myomatosus.
abstract: BACKGROUND
  Cutaneous mosaicism is a possible cause of segmental skin diseases. Cutaneous leiomyomatosis represent a spectrum of conditions ranging from single lesions to disseminated wide distribution. Reed's syndrome, is an autosomal dominant disorder characterized by multiple cutaneous and uterine leiomyomas.
  
  
  METHODS
  We observed a segmental cutaneous piloleimyomatosis type 1 in a 55-year old female who had an uterus extirpation because of uterine leiomyomas. The cutaneous lesions were moderately painful and localized on her left upper trunk. They presented as firm nodules and small plaques in a linear arrangement. Renal cancer was excluded.
  
  
  CONCLUSIONS
  In patients with multiple cutaneous (pilo)leiomyomas a search for underlying systemic diseases is necessary in order to not miss benign or malignant tumors of internal organs.
authors.affiliation: Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, 01067 Dresden, Germany;
authors.forename: Uwe
authors.initials: U
authors.lastname: Wollina
authors.affiliation: Institute of Pathology "Georg Schmorl", Academic Teaching Hospital Dresden-Friedrichstadt, 01067 Dresden, Germany.
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Schönlebe
keywords: kidney; mosacisim; myomas; nodules; piloleiomyomas; smooth muscle cells