title: Neutral redox-active hydrogen- and halogen-bonding [2]rotaxanes for the electrochemical sensing of chloride.
abstract: The first examples of redox-active ferrocene-functionalised neutral [2]rotaxanes have been synthesised via chloride anion templation. (1)H NMR spectroscopic titrations reveal that these [2]rotaxane host systems recognize chloride selectively over other halides and oxoanions in highly-competitive aqueous media. By replacing the hydrogen bonding prototriazole units of the rotaxane axle component with iodotriazole halogen bond-donor groups, the degree of chloride selectivity of the [2]rotaxanes is modulated. Electrochemical voltammetric experiments demonstrate that the rotaxanes can sense chloride via cathodic perturbations of the respective rotaxanes' ferrocene-ferrocenium redox-couple upon anion addition.
authors.affiliation: Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, UK. paul.beer@chem.ox.ac.uk.
authors.forename: Jason Y C
authors.initials: JY
authors.lastname: Lim
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Cunningham
authors.forename: Jason J
authors.initials: JJ
authors.lastname: Davis
authors.forename: Paul D
authors.initials: PD
authors.lastname: Beer
mesh_terms: D002623:Chemistry Techniques, Analytical / Q000379:methods*; D002712:Chlorides / Q000032:analysis* / Q000737:chemistry; D004563:Electrochemistry; D006219:Halogens / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D006860:Hydrogen Bonding; D009682:Magnetic Resonance Spectroscopy; D010084:Oxidation-Reduction; D043862:Rotaxanes / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D002712:Chlorides; D006219:Halogens; D043862:Rotaxanes; D006859:Hydrogen