title: A facile and general approach to 3-((trifluoromethyl)thio)-4H-chromen-4-one.
abstract: A facile and efficient synthetic strategy to 3-((trifluoromethyl)thio)-4H-chromen-4-one was developed. AgSCF3 and trichloroisocyanuric acid were employed here to generate active electrophilic trifluoromethylthio species in situ. This reaction could proceed under mild conditions in a short reaction time and be insensitive to air and moisture.
authors.affiliation: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , 555 Zuchongzhi Road, Shanghai, 201203, China.
authors.forename: Haoyue
authors.initials: H
authors.lastname: Xiang
authors.forename: Chunhao
authors.initials: C
authors.lastname: Yang
mesh_terms: D002384:Catalysis; D002867:Chromones / Q000138:chemical synthesis* / Q000737:chemistry; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D015394:Molecular Structure; D012834:Silver / Q000737:chemistry*; D014227:Triazines / Q000737:chemistry*
chemical_list: C000594954:3-((trifluoromethyl)thio)-4H-chromen-4-one; D002867:Chromones; D006846:Hydrocarbons, Halogenated; D014227:Triazines; C557580:trichloroisocyanuric acid; D012834:Silver