title: Antibacterial activity of ethyl acetate and aqueous extracts of Mentha longifolia L. and hydroalcoholic extract of Zataria multiflora Boiss. plants against important human pathogens.
abstract: OBJECTIVE
  To determine the potential antibacterial activity of ethyl acetate and aqueous extracts from Mentha longifolia L. (M. longifolia) and hydroalcoholic extract of Zataria multiflora Boiss. (Z. multiflora) against important human pathogens.
  
  
  METHODS
  Pseudomonas aeruginosa, Shigella dysenteriae, Klebsiella pneumoniae (K. pneumonia), Enterobacter cloacae, Salmonella typhi, Proteus mirabilis, Serratia marcescens, Bacillus cereus, Staphylococcus saprophyticus and Staphylococcus aureus were kinds of pathogenic bacteria to determine the antibacterial effect of aqueous and ethyl acetate extracts of M. longifolia and hydroalcoholic extract of Z. multiflora using broth microdiluation method.
  
  
  RESULTS
  The lowest minimum inhibitory concentration and minimum bactericidal concentration values for K. pneumonia and Pseudomonas aeruginosa (1.25 and 2.5 mg/mL) were observed by the hydroalcoholic extract of Z. multiflora and the lowest minimum inhibitory concentration and minimum bactericidal concentration values for K. pneumonia and Serratia marcescens (2.5 and 5 mg/mL) were observed by the aqueous extracts of M. longifolia.
  
  
  CONCLUSIONS
  In conclusion, it seems that Z. multiflora and M. longifolia extracts could inhibit the growth of all of the mentioned bacteria.
authors.affiliation: Department of Agronomy and Plant Breeding, Agriculture Research Center, Zabol University, Zabol, Iran.
authors.forename: Saeide
authors.initials: S
authors.lastname: Saeidi
authors.affiliation: Medical School, Sabzevar University of Medical Sciences, Sabzevar, Iran.
authors.forename: Kazem
authors.initials: K
authors.lastname: Hassanpour
authors.affiliation: Neurosciences Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Ghamgosha
authors.affiliation: Applied Biotechnology Research Centre, Baqiyatallah University of Medical Sciences, Tehran, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Heiat
authors.affiliation: Nanobiotechnology Research Centre, Baqiyatallah University of Medical Sciences, Tehran, Iran.
authors.forename: Ramezan Ali
authors.initials: RA
authors.lastname: Taheri
authors.affiliation: Applied Microbiology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Mirhosseini
authors.affiliation: Applied Biotechnology Research Centre, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: rzfarnoosh@yahoo.com.
authors.forename: Gholamreza
authors.initials: G
authors.lastname: Farnoosh
keywords: Antibacterial activity; Human pathogen; Mentha longifolia L.; Zataria multiflora Boiss.