title: [Effect of regenerative therapy for the furcation involvements of mandibular molars evaluated by cone-beam computed tomography].
abstract: OBJECTIVE
  To evaluate the effect of regenerative therapy for the treatment of furcation involvements of mandibular molars with cone-beam computed tomography (CBCT).
  
  
  METHODS
  In the study, 38 furcation involvements of mandibular molars were included and randomly divided into two groups. The experimental group accepted guided tissue regeneration and bone graft therapy, and the control group only flap surgery. The clinical examination and CBCT examination were performed at baseline and 1 year post-surgery.
  
  
  RESULTS
  The clinical and CBCT data of both groups were not statistically different at baseline (P>0.05). At the end of 1 year post-surgery, except gingival recession, the clinical parameters of both groups were significantly improved (P<0.001). The vertical and horizontal attachment gains of the experimental group were (3.20 ± 1.82) mm and (2.05 ± 1.27) mm, respectively, and significantly higher than the changes of the control group (P<0.001). And at the end of 1 year post-surgery, the experimental group showed significantly higher bone gain at the vertical and horizontal directions compared with those of the control group: (2.82 ± 0.97) mm and (2.24 ± 0.92) mm, respectively (P<0.001).
  
  
  CONCLUSIONS
  With the limitation of this study, the effect of guided tissue regeneration surgery and bone graft therapy for the treatment of furcation involvements of mandibular molars is significantly better than that of the flap surgery. CBCT can reflect the horizontal and vertical bone changes of furcation area, which is more comprehensive than traditional periapicals.
authors.affiliation: The First Outpatient Center, Peking University School and Hospital of Stomatology, Beijing 100034, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Qiao
authors.affiliation: The First Outpatient Center, Peking University School and Hospital of Stomatology, Beijing 100034, China.
authors.forename: Jin-yu
authors.initials: JY
authors.lastname: Duan
authors.affiliation: The First Outpatient Center, Peking University School and Hospital of Stomatology, Beijing 100034, China.
authors.forename: Chang-zhou
authors.initials: CZ
authors.lastname: Sun
authors.affiliation: Department of Oral Radiology, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Deng-gao
authors.initials: DG
authors.lastname: Liu
mesh_terms: D016025:Bone Transplantation; D054893:Cone-Beam Computed Tomography; D005500:Follow-Up Studies; D017823:Furcation Defects; D005889:Gingival Recession; D016557:Guided Tissue Regeneration, Periodontal; D006801:Humans; D008963:Molar; D013524:Surgical Flaps; D016896:Treatment Outcome