title: Comparison of clinical outcomes of Chinese men and women after coronary stenting for coronary artery disease: a multi-center retrospective analysis of 4,334 patients.
abstract: The outcome differences between Chinese male and female patients within one-year follow-up after percutaneous coronary intervention (PCI) with stent remain unclear. The present study was aimed to compare clinical outcomes in such two populations. From May 1999 to December 2009, 4,334 patients with acute myocardial infarction (MI), unstable angina, stable angina, or silent ischemia, who underwent PCI, were registered at our centers. Among these, 3,089 were men and 1,245 were women. We compared these groups with respect to the primary outcomes of MI and secondary outcomes including a composite of major adverse cardiac events (MACE) including cardiac death, MI, target lesion revascularization, target vessel revascularization (TVR), stent thrombosis (ST), definite ST and probable ST at one-year follow-up. Chinese male patients had a higher MACE rate (13% vs. 10.7%, P  =  0.039), mainly led by TVR (9.09% vs. 6.98%, P = 0.024) at one year, which was significantly different than female patients. Chinese male and female patients showed a significant difference on MACEs. However, there was no significant difference with respect to MI between these groups.
authors.affiliation: Department of Cardiology, Nanjing Medical University, Nanjing, Jiangsu 210029, China.
authors.forename: Rajiv
authors.initials: R
authors.lastname: Shrestha
authors.affiliation: Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Xu
authors.affiliation: Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, China.
authors.forename: Dujiang
authors.initials: D
authors.lastname: Xie
authors.affiliation: Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, China.
authors.forename: Zhizhong
authors.initials: Z
authors.lastname: Liu
authors.affiliation: Department of Cardiology, Nanjing Medical University, Nanjing, Jiangsu 210029, China.
authors.forename: Tian
authors.initials: T
authors.lastname: Xu
authors.affiliation: Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Ye
authors.affiliation: Department of Cardiology, Huainan Xinhua Hospital, Huainan, Anhui 232038, China.
authors.forename: Shiqing
authors.initials: S
authors.lastname: Din
authors.affiliation: Department of Cardiology, Zhangjiagang People's Hospital, Zhangjiagang, Jiangsu 215600, China.
authors.forename: Xuesong
authors.initials: X
authors.lastname: Qian
authors.affiliation: Department of Cardiology, Yixin People's Hospital, Yixin, Jiangsu 214200, China.
authors.forename: Song
authors.initials: S
authors.lastname: Yang
authors.affiliation: Department of Cardiology, Jintan People's Hospital, Jintan, Jiangsu 213200, China.
authors.forename: Yueqiang
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Cardiology, Huainan Oriental General Hospital, Huainan, Anhui 235056, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Li
authors.affiliation: Department of Cardiology, Huainan People's Hospital, Huainan, Anhui 340016, China.
authors.forename: Aiping
authors.initials: A
authors.lastname: Zhang
authors.affiliation: Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, China.
authors.forename: Shaoliang
authors.initials: S
authors.lastname: Chen
keywords: coronary stenting; drug-eluting stent; gender difference; interventional cardiology; ischemic heart disease; major adverse cardiac event