title: Computer simulations of phase separation in lipid bilayers and monolayers.
abstract: Studying phase coexistence in lipid bilayers and monolayers is important for understanding lipid-lipid interactions underlying lateral organization in biological membranes. Computer simulations follow experimental approaches and use model lipid mixtures of simplified composition. Atomistic simulations give detailed information on the specificity of intermolecular interactions, while coarse-grained simulations achieve large time and length scales and provide a bridge towards state-of-the-art experimental techniques. Computer simulations allow characterizing the structure and composition of domains during phase transformations at Angstrom and picosecond resolution, and bring new insights into phase behavior of lipid membranes.
authors.affiliation: Department of Biological Sciences, Centre for Molecular Simulation, University of Calgary, 2500 University Dr. NW, Calgary, AB, Canada, T2N 1N4, s.baoukina@ucalgary.ca.
authors.forename: Svetlana
authors.initials: S
authors.lastname: Baoukina
authors.forename: D Peter
authors.initials: DP
authors.lastname: Tieleman
mesh_terms: D008051:Lipid Bilayers / Q000737:chemistry*; D008563:Membrane Lipids / Q000737:chemistry; D021962:Membrane Microdomains / Q000737:chemistry; D056004:Molecular Dynamics Simulation; D013696:Temperature
chemical_list: D008051:Lipid Bilayers; D008563:Membrane Lipids