title: Asenapine-induced restless legs syndrome: differentiation from akathisia.
abstract: Akathisia and restless legs syndrome (RLS) share some common clinical features and a common relationship with dopamine dysfunction. However, the underlying causes and appropriate treatments for akathisia and RLS are different. Herein we describe a case of RLS that was precipitated by a single dose of asenapine, which is an atypical antipsychotic, and dissect the features that support the contention that this was indeed a case of RLS and not akathisia.
authors.affiliation: Department of Psychiatry and Health Behavior, The Medical College of Georgia, Georgia Regents University, Augusta, GA.
authors.forename: W Vaughn
authors.initials: WV
authors.lastname: McCall
authors.affiliation: Department of Psychiatry and Health Behavior, The Medical College of Georgia, Georgia Regents University, Augusta, GA.
authors.forename: Mary Anne
authors.initials: MA
authors.lastname: Riley
authors.affiliation: Department of Psychiatry and Health Behavior, The Medical College of Georgia, Georgia Regents University, Augusta, GA.
authors.forename: Chelsea
authors.initials: C
authors.lastname: Hodges
authors.affiliation: Department of Psychiatry and Health Behavior, The Medical College of Georgia, Georgia Regents University, Augusta, GA.
authors.forename: Laryssa
authors.initials: L
authors.lastname: McCloud
authors.affiliation: Pharmacy Department, Georgia Regents Medical Center, Augusta, GA.
authors.forename: Marjorie
authors.initials: M
authors.lastname: Phillips
authors.affiliation: Department of Psychiatry and Health Behavior, The Medical College of Georgia, Georgia Regents University, Augusta, GA.
authors.forename: Peter B
authors.initials: PB
authors.lastname: Rosenquist
mesh_terms: D014150:Antipsychotic Agents / Q000009:adverse effects*; D003937:Diagnosis, Differential; D003986:Dibenzocycloheptenes; D005260:Female; D006576:Heterocyclic Compounds, 4 or More Rings / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D011595:Psychomotor Agitation; D012148:Restless Legs Syndrome / Q000139:chemically induced*
chemical_list: D014150:Antipsychotic Agents; D003986:Dibenzocycloheptenes; D006576:Heterocyclic Compounds, 4 or More Rings; C522667:asenapine
keywords: akathisia; asenapine; restless leg syndrome