title: Cardiovascular variability in Mexican patients with Parkinson's disease.
abstract: Cardiovascular variability (CVV) has been evaluated in patients with Parkinson's disease (PD) in other countries and exhibit ethnic differences.
  
  
  OBJECTIVE
  We investigated heart rate variability (HRV) and blood pressure variability (BPV) in Mexican patients with PD.
  
  
  METHODS
  We further compared HRV and BPV between this group and young healthy controls (YHC) in order to estimate, for the first time in our country, the magnitude of the difference. Twenty patients were examined. Time- and frequency-domain CVV parameters were studied during supine rest (SR), active standing (AS) and controlled breathing. These measurements were compared to those of 20 YHC.
  
  
  RESULTS
  In the three conditions tested, our study showed a decrease in almost all HRV parameters in PD patients; on the contrary, decreased BPV parameters were found less frequently and only during SR and AS.
  
  
  CONCLUSIONS
  Our results indicate that HRV is impaired in PD. Some BPV parameters are also diminished.
authors.affiliation: Laboratory of Clinical Neurophysiology, Department of Neurology and Psychiatry, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Monterrey, Nuevo León, Mexico.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Delgado
authors.affiliation: Laboratory of Clinical Neurophysiology, Department of Neurology and Psychiatry, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Monterrey, Nuevo León, Mexico.
authors.forename: Bruno
authors.initials: B
authors.lastname: Estañol
authors.affiliation: National Institute of Neurology and Neurosurgery Manuel Velasco Suárez, Mexico, DF, Mexico.
authors.forename: Mayela
authors.initials: M
authors.lastname: Rodríguez-Violante
authors.affiliation: Department of Electromechanical Instrumentation, National Institute of Cardiology Ignacio Chávez, Mexico, DF, Mexico.
authors.forename: Raúl
authors.initials: R
authors.lastname: Martínez-Memije
authors.affiliation: Department of Electromechanical Instrumentation, National Institute of Cardiology Ignacio Chávez, Mexico, DF, Mexico.
authors.forename: Óscar
authors.initials: Ó
authors.lastname: Infante-Vázquez
authors.affiliation: Laboratory of Clinical Neurophysiology, Department of Neurology and Psychiatry, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Monterrey, Nuevo León, Mexico.
authors.forename: Nancy
authors.initials: N
authors.lastname: Bertado-Ramírez
mesh_terms: D001794:Blood Pressure / Q000502:physiology*; D016022:Case-Control Studies; D004562:Electrocardiography; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D008800:Mexico; D008875:Middle Aged; D010300:Parkinson Disease / Q000503:physiopathology*