title: Overwhelming hypercalcaemia in mandibular ameloblastoma.
abstract: Ameloblastoma is considered to be a benign odontogenic tumour of epithelial in origin that is slow growing but recurrent and invasive in nature. Some of its features have been sources of debate among experts regarding its benign or malignant character. We report a case of a 20-year-old Filipino woman with right mandibular ameloblastoma presenting with overwhelming hypercalcaemia. Work ups for hypercalcaemia eventually revealed tumoral hypercalcaemia, which was initially controlled with intravenous bisphosphanate. The patient eventually underwent tumour excision and mandibular reconstruction, which totally corrected hypercalcaemia. This case will highlight the rare association of hypercalcaemia among patients with ameloblastoma.
authors.affiliation: Department of Medicine-Endocrinology, University of the Philippines-Philippine General Hospital, Manila, Philippines.
authors.forename: Tom Edward Ngo
authors.initials: TE
authors.lastname: Lo
authors.affiliation: Department of Otorhinolaryngology, University of the Philippines-Philippine General Hospital, Manila, Philippines.
authors.forename: Cesar Vincent
authors.initials: CV
authors.lastname: Villafuerte
authors.affiliation: Department of Medicine-Endocrinology, University of the Philippines-Philippine General Hospital, Manila, Philippines.
authors.forename: Laura Trajano
authors.initials: LT
authors.lastname: Acampado
mesh_terms: D000328:Adult; D000564:Ameloblastoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D008334:Mandible / Q000473:pathology / Q000601:surgery; D008339:Mandibular Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult