title: Hemophagocytic Lymphohistiocytosis (HLH) Associated with T-Cell Lymphomas: Broadening our Differential for Fever of Unknown Origin.
abstract: BACKGROUND
  Hemophagocytic lymphohistiocytosis (HLH), due to the excessive activity of histiocytes and lymphocytes, is a rare but aggressive disease that typically occurs in infancy but can be seen in all ages. If left untreated, patients with HLH may live for only a few months and die from multi-organ failure.
  
  
  METHODS
  We present two cases of HLH diagnosis. Fever, spleen, and hepatic abnormalities were noted in both cases.
  
  
  CONCLUSIONS
  Early diagnosis is the key and these two cases of similar etiology highlight how fever of unknown origin should force us to broaden our differential.
authors.affiliation: Department of Medicine, University of Vermont, Vermont, USA.
authors.forename: Sherrie
authors.initials: S
authors.lastname: Khadanga
authors.affiliation: Department of Medicine, University of Vermont, Vermont, USA.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Solomon
authors.affiliation: Division of Hematology/Oncology, University of Vermont, Vermont, USA.
authors.forename: Kim
authors.initials: K
authors.lastname: Dittus
keywords: Fever of unknown origin; Hemophagocytic lymphohistiocytosis; T-cell lymphoma