title: [The indicators of immune status of peripheral blood of donors].
abstract: The expanded analysis of 57 samples of peripheral blood from conditionally healthy patients was implemented concerning phenotype of main populations of lymphocytes, activated pools of cells and level of cytokines. The samples were received in the department of storage of blood and its components of the research institute of blood transfusion of the hematology research center. It is demonstrated that number of T-lymphocytes, T-helpers and activated TY-cells with phenotype CD3+HLA-R+ and level of detected cytokines by standard indicators had no difference with publications data. In particular cases an increase of number of cytolytic T-lymphocytes, B-lymphocytes and natural killers and decrease or increase of CD4/CD8 index relative to standard were detected. The decrease of number of natural killers was the most frequent aberration. The study demonstrates that among conditionally healthy patients giving blood as donors persons with disorders of immune system were presented.
authors.forename: L M
authors.initials: LM
authors.lastname: Selimova
authors.forename: L V
authors.initials: LV
authors.lastname: Serebrovskaya
authors.forename: L B
authors.initials: LB
authors.lastname: Kalnina
authors.forename: O N
authors.initials: ON
authors.lastname: Khokhlova
authors.forename: A N
authors.initials: AN
authors.lastname: Guliyaeva
authors.forename: D N
authors.initials: DN
authors.lastname: Nosik
mesh_terms: D000293:Adolescent; D000328:Adult; D001771:Blood Banks / Q000592:standards; D001782:Blood Donors; D016516:CD4-CD8 Ratio / Q000592:standards*; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged