title: Impact of Surgical Infection Society/Infectious Disease Society of America-recommended antibiotics on postoperative intra-abdominal abscess with image-guided percutaneous abscess drainage following gastrointestinal surgery.
abstract: OBJECTIVE
  The aims of this study were to reveal how using the antibiotics recommended by the 2010 Surgical Infection Society (SIS) and Infectious Disease Society of America (IDSA) guidelines can affect the therapeutic outcomes.
  
  
  METHODS
  We reviewed the cases of 53 patients with a postoperative intra-abdominal abscess without anastomotic leakage after gastrointestinal surgery who underwent image-guided percutaneous abscess drainage (PAD) and concomitant antibiotic therapy. The type of antibiotic initially administered was determined based on the surgeon's judgment. A persistent abscess was defined as one or more PAD procedures resulting in complete resolution after 21 or more days. The recommended antibiotics were defined according to 2010 SIS/IDSA guidelines.
  
  
  RESULTS
  All 53 patients had complete resolution without the need for surgery. The results of a multivariable analysis revealed that a C-reactive protein level ≥12 mg/dL and non-recommended antibiotics were significant risk factors for a persistent abscess (P = 0.042 and 0.013, respectively). With regard to a fever lasting more than 48 h, there was a significant difference between the recommended (45.1%) and non-recommended (72.7 %) antibiotic groups (P = 0.046).
  
  
  CONCLUSIONS
  Using the recommended antibiotics may shorten the time to defervescence and reduce the risk of a persistent abscess in patients undergoing PAD for a postoperative abscess after gastrointestinal surgery.
authors.affiliation: Department of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, Tsu, Japan, nyokkin@clin.medic.mie-u.ac.jp.
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Okita
authors.forename: Minako
authors.initials: M
authors.lastname: Kobayashi
authors.forename: Toshimitsu
authors.initials: T
authors.lastname: Araki
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Fujikawa
authors.forename: Yuhki
authors.initials: Y
authors.lastname: Koike
authors.forename: Koike
authors.initials: K
authors.lastname: Yuki
authors.forename: Kohei
authors.initials: K
authors.lastname: Otake
authors.forename: Otake
authors.initials: O
authors.lastname: Kohei
authors.forename: Inoue
authors.initials: I
authors.lastname: Mikihiro
authors.forename: Inoue
authors.initials: I
authors.lastname: Mikihiro
authors.forename: Yuji
authors.initials: Y
authors.lastname: Toiyama
authors.forename: Toiyama
authors.initials: T
authors.lastname: Yuji
authors.forename: Masaki
authors.initials: M
authors.lastname: Ohi
authors.forename: Msaki
authors.initials: M
authors.lastname: Ohi
authors.forename: Koji
authors.initials: K
authors.lastname: Tanaka
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Inoue
authors.forename: Keiichi
authors.initials: K
authors.lastname: Uchida
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Mohri
authors.forename: Koichiro
authors.initials: K
authors.lastname: Yamakado
authors.forename: Masato
authors.initials: M
authors.lastname: Kusunoki
mesh_terms: D018784:Abdominal Abscess / Q000628:therapy*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D013505:Digestive System Surgical Procedures; D004322:Drainage; D005260:Female; D013502:General Surgery / Q000458:organization & administration*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000628:therapy*; D017410:Practice Guidelines as Topic; D012307:Risk Factors; D012955:Societies, Medical / Q000458:organization & administration*; D025321:Surgery, Computer-Assisted; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents