title: Stroke: 'time is brain' after stroke, regardless of age and severity.
abstract: Two recent studies highlight the importance of prompt, coordinated intervention after stroke. A meta-analysis confirms that intravenous thrombolysis is effective within 4.5 h of onset, irrespective of age (below or above 80 years) and stroke severity. Another study demonstrates successful reorganization of care through centralization of stroke services in England.
authors.affiliation: Klinik für Neurologie &Center for Stroke Research Berlin (CSB), Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany.
authors.forename: Heinrich J
authors.initials: HJ
authors.lastname: Audebert
authors.affiliation: Klinik für Neurologie &Center for Stroke Research Berlin (CSB), Charité Universitätsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.
authors.forename: Jan
authors.initials: J
authors.lastname: Sobesky
mesh_terms: D000367:Age Factors; D001921:Brain / Q000187:drug effects / Q000503:physiopathology; D002497:Centralized Hospital Services / Q000379:methods; D004739:England; D006801:Humans; D012720:Severity of Illness Index; D020521:Stroke / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D015912:Thrombolytic Therapy / Q000379:methods; D061665:Time-to-Treatment