title: Amine-accelerated manganese-catalyzed aromatic C-H conjugate addition to α,β-unsaturated carbonyls.
abstract: Since 1987, the stoichiometric two-step C-H conjugate addition reactions have been developed. Herein we describe the first manganese-catalyzed one-step direct aromatic C-H conjugate addition to α,β-unsaturated carbonyls, which is accelerated by a catalytic amount of dicyclohexylamine. Experimental and computational studies substantiated the validity of the proposed catalytic cycle.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. wangcy@iccas.ac.cn.
authors.forename: Bingwei
authors.initials: B
authors.lastname: Zhou
authors.forename: Pengchen
authors.initials: P
authors.lastname: Ma
authors.forename: Hui
authors.initials: H
authors.lastname: Chen
authors.forename: Congyang
authors.initials: C
authors.lastname: Wang