title: Effectiveness of a standardized treatment protocol for children with active non-cavitated occlusal lesions on erupting permanent molars.
abstract: OBJECTIVE
  To evaluate the effectiveness of a treatment for non-cavitated occlusal lesions on erupting permanent molars and to verify whether initial eruption stage and final biofilm accumulation are associated with lesions activity after the treatment.
  
  
  METHODS
  Forty-eight patients aged from 5 to 13 years old were selected. Molars with active non-cavitated lesions on the occlusal surface were classified according to eruption stage. Patients received a treatment for 4 weeks based on oral health instructions and fluoride applications. Three weeks after the end of the treatment, 39 patients were reassessed and lesion activity status and biofilm accumulation were recorded. Odds ratios were obtained using generalized estimating equations with logistic link function.
  
  
  RESULTS
  Partially erupted molars were more prone to remain caries-active than molars in full occlusion (E1: OR = 301.1; E2: OR = 49.0 and E3: OR = 1107.3). High biofilm accumulation was associated with the presence of active lesions.
  
  
  CONCLUSIONS
  Biofilm accumulation and eruption stage strongly influenced the effectiveness of a treatment for dental caries.
authors.affiliation: Department of Pediatric Dentistry, School of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.|Faculdade da Serra Gaúcha, Caxias do Sul, Rio Grande do Sul, Brazil.
authors.forename: Renata Schlesner
authors.initials: RS
authors.lastname: de Oliveira
authors.affiliation: Department of Stomatology, School of Dentistry, Federal University of Santa Maria, Santa Maria, Brazil.
authors.forename: Júlio Eduardo do Amaral
authors.initials: JE
authors.lastname: Zenkner
authors.affiliation: Department Social and Preventive Dentistry, School of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
authors.forename: Marisa
authors.initials: M
authors.lastname: Maltz
authors.affiliation: Department of Pediatric Dentistry, School of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
authors.forename: Jonas Almeida
authors.initials: JA
authors.lastname: Rodrigues
mesh_terms: D000149:Acidulated Phosphate Fluoride / Q000627:therapeutic use*; D000293:Adolescent; D018441:Biofilms / Q000254:growth & development*; D002648:Child; D002675:Child, Preschool; D002985:Clinical Protocols; D003731:Dental Caries / Q000382:microbiology / Q000628:therapy*; D003766:Dental Occlusion; D005260:Female; D006801:Humans; D008297:Male; D008963:Molar / Q000254:growth & development*; D014078:Tooth Eruption / Q000502:physiology*; D014099:Toothbrushing
chemical_list: C074808:NuPro; D000149:Acidulated Phosphate Fluoride