title: Long-term survival after enucleation of a giant esophageal gastrointestinal stromal tumor.
abstract: Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms of the gastrointestinal tract. Less than 1% occurs in the esophagus. Surgery is the primary treatment for patients with GISTs. We report a 29-year-old male was admitted after the detection of a posterior mediastinal mass during work-up with routine examination. He did not have any disease-related symptoms. The physical examination was unremarkable. Chest computed tomographic scan, the barium esophagogram and endoscopic esophageal ultrasound showed benign neoplasm. The patient was performed an enucleation surgery through the right posterolateral thoracotomy. The pathology revealed a 13.0 cm × 12.0 cm × 5.0 cm mass. The tumor was CD117 (C-kit), PDGFRA and DOG1 positive. These findings were consistent with a GIST of the esophagus. So the diagnosis of GIST of esophagus was confirmed. The pathological diagnosis of low grade of GIST of esophagus was confirmed. The patient has no evidence of recurrence and is in good clinical conditions up-to date, five years after surgery.
authors.affiliation: Zhi-Min Mu, Yuan-Cai Xie, Xu-Xing Peng, Hai Zhang, Gang Hui, Hao Wu, Ji-Xian Liu, Bao-Kun Chen, Da Wu, Yi-Wang Ye, Department of thoracic surgery, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China.
authors.forename: Zhi-Min
authors.initials: ZM
authors.lastname: Mu
authors.affiliation: Zhi-Min Mu, Yuan-Cai Xie, Xu-Xing Peng, Hai Zhang, Gang Hui, Hao Wu, Ji-Xian Liu, Bao-Kun Chen, Da Wu, Yi-Wang Ye, Department of thoracic surgery, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China.
authors.forename: Yuan-Cai
authors.initials: YC
authors.lastname: Xie
authors.affiliation: Zhi-Min Mu, Yuan-Cai Xie, Xu-Xing Peng, Hai Zhang, Gang Hui, Hao Wu, Ji-Xian Liu, Bao-Kun Chen, Da Wu, Yi-Wang Ye, Department of thoracic surgery, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China.
authors.forename: Xu-Xing
authors.initials: XX
authors.lastname: Peng
authors.affiliation: Zhi-Min Mu, Yuan-Cai Xie, Xu-Xing Peng, Hai Zhang, Gang Hui, Hao Wu, Ji-Xian Liu, Bao-Kun Chen, Da Wu, Yi-Wang Ye, Department of thoracic surgery, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China.
authors.forename: Hai
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Zhi-Min Mu, Yuan-Cai Xie, Xu-Xing Peng, Hai Zhang, Gang Hui, Hao Wu, Ji-Xian Liu, Bao-Kun Chen, Da Wu, Yi-Wang Ye, Department of thoracic surgery, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Hui
authors.affiliation: Zhi-Min Mu, Yuan-Cai Xie, Xu-Xing Peng, Hai Zhang, Gang Hui, Hao Wu, Ji-Xian Liu, Bao-Kun Chen, Da Wu, Yi-Wang Ye, Department of thoracic surgery, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Wu
authors.affiliation: Zhi-Min Mu, Yuan-Cai Xie, Xu-Xing Peng, Hai Zhang, Gang Hui, Hao Wu, Ji-Xian Liu, Bao-Kun Chen, Da Wu, Yi-Wang Ye, Department of thoracic surgery, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China.
authors.forename: Ji-Xian
authors.initials: JX
authors.lastname: Liu
authors.affiliation: Zhi-Min Mu, Yuan-Cai Xie, Xu-Xing Peng, Hai Zhang, Gang Hui, Hao Wu, Ji-Xian Liu, Bao-Kun Chen, Da Wu, Yi-Wang Ye, Department of thoracic surgery, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China.
authors.forename: Bao-Kun
authors.initials: BK
authors.lastname: Chen
authors.affiliation: Zhi-Min Mu, Yuan-Cai Xie, Xu-Xing Peng, Hai Zhang, Gang Hui, Hao Wu, Ji-Xian Liu, Bao-Kun Chen, Da Wu, Yi-Wang Ye, Department of thoracic surgery, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China.
authors.forename: Da
authors.initials: D
authors.lastname: Wu
authors.affiliation: Zhi-Min Mu, Yuan-Cai Xie, Xu-Xing Peng, Hai Zhang, Gang Hui, Hao Wu, Ji-Xian Liu, Bao-Kun Chen, Da Wu, Yi-Wang Ye, Department of thoracic surgery, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China.
authors.forename: Yi-Wang
authors.initials: YW
authors.lastname: Ye
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis / Q000235:genetics; D001706:Biopsy; D004252:DNA Mutational Analysis; D019160:Endosonography; D004938:Esophageal Neoplasms / Q000737:chemistry / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D016629:Esophagectomy / Q000379:methods; D046152:Gastrointestinal Stromal Tumors / Q000737:chemistry / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009154:Mutation; D060787:Neoplasm Grading; D011237:Predictive Value of Tests; D013908:Thoracotomy; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D047368:Tumor Burden
chemical_list: D014408:Biomarkers, Tumor
keywords: Enucleation; Esophageal gastrointestinal stromal tumor; Follow-up; Long-term survival; Surgery