title: Slow wave conduction patterns in the stomach: from Waller's foundations to current challenges.
abstract: This review provides an overview of our understanding of motility and slow wave propagation in the stomach. It begins by reviewing seminal studies conducted by Walter Cannon and Augustus Waller on in vivo motility and slow wave patterns. Then our current understanding of slow wave patterns in common laboratory animals and humans is presented. The implications of slow wave arrhythmic patterns that have been recorded in animals and patients suffering from gastroparesis are discussed. Finally, current challenges in experimental methods and techniques, slow wave modulation and the use of mathematical models are discussed.
authors.affiliation: Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand; Department of Surgery, Vanderbilt University, Nashville, TN, USA.
authors.forename: L K
authors.initials: LK
authors.lastname: Cheng
mesh_terms: D000818:Animals; D001145:Arrhythmias, Cardiac / Q000503:physiopathology*; D002465:Cell Movement / Q000502:physiology; D055590:Electromagnetic Phenomena; D006801:Humans; D008954:Models, Biological; D009119:Muscle Contraction / Q000502:physiology*; D013270:Stomach / Q000502:physiology*
keywords: arrhythmia; gastroparesis; interstitial cells of Cajal; slow wave patterns; smooth muscle