title: [Lung cancer screening with low dose CT requires careful consideration].
abstract: Results from the American National Lung Screening Trial (NLST) show a significant reduction in lung cancer and all-cause mortality in a high risk population screened with annual low-dose CT. Handling of pulmonary nodules, false positive tests, overdiagnosis, psychosocial consequences and cost-efficiency etc. are all aspects that require careful consideration. This paper gives an overview of the current knowledge on these issues. Before a recommendation can be made, we need an overall evaluation of both the benefits and harms in CT screening for lung cancer.
authors.affiliation: Horsensgade 12, 5., 2100 København Ø. zaigham.saghir@gmail.com.
authors.forename: Zaigham
authors.initials: Z
authors.lastname: Saghir
authors.forename: Asger
authors.initials: A
authors.lastname: Dirksen
authors.forename: Haseem
authors.initials: H
authors.lastname: Ashraf
authors.forename: Karen Skjøldstrup
authors.initials: KS
authors.lastname: Bach
authors.forename: John
authors.initials: J
authors.lastname: Brodersen
authors.forename: Paul Frost
authors.initials: PF
authors.lastname: Clementsen
authors.forename: Martin
authors.initials: M
authors.lastname: Døssing
authors.forename: Hanne
authors.initials: H
authors.lastname: Hansen
authors.forename: Klaus Fuglsang
authors.initials: KF
authors.lastname: Kofoed
authors.forename: Klaus Richter
authors.initials: KR
authors.lastname: Larsen
authors.forename: Jann
authors.initials: J
authors.lastname: Mortensen
authors.forename: Jakob Fraes
authors.initials: JF
authors.lastname: Rasmussen
authors.forename: Laura Hohwü
authors.initials: LH
authors.lastname: Thomsen
authors.forename: Mathilde Marie Winkler
authors.initials: MM
authors.lastname: Wille
authors.forename: Niels
authors.initials: N
authors.lastname: Seersholm
authors.forename: Birgit Guldhammer
authors.initials: BG
authors.lastname: Skov
authors.forename: Hanne
authors.initials: H
authors.lastname: Thorsen
authors.forename: Philip
authors.initials: P
authors.lastname: Tønnesen
authors.forename: Jesper Holst
authors.initials: JH
authors.lastname: Pedersen
mesh_terms: D003362:Cost-Benefit Analysis; D003951:Diagnostic Errors; D055088:Early Detection of Cancer; D005189:False Positive Reactions; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging*; D008403:Mass Screening / Q000191:economics / Q000523:psychology / Q000592:standards; D011829:Radiation Dosage; D012307:Risk Factors; D012907:Smoking / Q000523:psychology; D014057:Tomography, X-Ray Computed / Q000379:methods