title: Vitamin D levels and left ventricular diastolic function.
abstract: To determine the association between serum vitamin D level and left ventricular (LV) diastolic dysfunction.
  
  
  
  Vitamin D deficiency has been shown in observational and prospective studies to be associated with cardiovascular diseases including coronary artery disease, LV hypertrophy and systolic heart failure. Even though diastolic LV dysfunction is an early manifestation of cardiac disease, there is no study that examines whether a deficiency of vitamin D is associated with LV diastolic dysfunction.
  
  
  
  A retrospective observational review of 1011 patients (679 women) was conducted to examine if low 25-OH-vitamin D levels were associated with LV diastolic dysfunction.
  
  
  
  ALL THE LV DIASTOLIC DYSFUNCTION PARAMETERS: left atrial volume index, E/e', e' velocity, LV mass index and deceleration time were not significantly different between patients with 25-OH vitamin D level ≤20 ng/mL vs 25-OH vitamin D level >20 ng/mL.
  
  
  
  Despite growing medical literature suggesting vitamin D deficiency is associated with cardiovascular disease, in this present study there is no significant association of vitamin D levels and LV diastolic performance, including left atrial volume index.
authors.affiliation: Division of Cardiovascular Diseases , Mayo Clinic , Scottsdale, Arizona , USA.
authors.forename: Anil
authors.initials: A
authors.lastname: Pandit
authors.affiliation: Division of Cardiovascular Diseases , Mayo Clinic , Scottsdale, Arizona , USA.
authors.forename: Farouk
authors.initials: F
authors.lastname: Mookadam
authors.affiliation: Division of Cardiovascular Diseases , Mayo Clinic , Scottsdale, Arizona , USA.
authors.forename: Sailaja
authors.initials: S
authors.lastname: Boddu
authors.affiliation: Division of Cardiovascular Diseases , Mayo Clinic , Scottsdale, Arizona , USA.
authors.forename: Aashrayata
authors.initials: A
authors.lastname: Aryal Pandit
authors.affiliation: Division of Cardiology , University of Utah , Salt Lake City, Utah , USA.
authors.forename: Anwar
authors.initials: A
authors.lastname: Tandar
authors.affiliation: Division of Cardiovascular Diseases , Mayo Clinic , Scottsdale, Arizona , USA.
authors.forename: Hari
authors.initials: H
authors.lastname: Chaliki
authors.affiliation: Division of Biomedical Informatics and Statistics , Mayo Clinic , Rochester, Minnesota , USA.
authors.forename: Stephen
authors.initials: S
authors.lastname: Cha
authors.affiliation: Division of Cardiovascular Diseases , Mayo Clinic , Scottsdale, Arizona , USA.
authors.forename: Howard R
authors.initials: HR
authors.lastname: Lee
keywords: Left ventricular diastolic dysfunction; Vitamin D deficiency; diastology