title: [Efficacy of CO2 laser in the treatment of precancerous laryngeal lesions under phonomicrosurgery and its relative factors].
abstract: OBJECTIVE
  To investigate the efficacy of CO2 laser treatment for patients with precancerous laryngeal lesions under phonomicrosurgery and to explore the points for attention in operation.
  
  
  METHODS
  They were all treated with phonomicrosurgery techniques as mucosal epitheliumablation or mucosal stripping by using CO2 laser. Eight patients with laryngeal papilloma were excised by CO2 laser.
  
  
  RESULTS
  All patients were treated with CO2 laser surgery successfully. During follow-up of 6 to 39 months, all patients survived. Local recurrence or canceration were detected in 3 cases, of which 2 cases with laryngeal papilloma underwent CO2 laser treatment in one year post-operatively, while the other case with severe dysplasia underwent laryngeal vertical partial laryngectomy and post-operative radiotherapy one and half year postoperatively due to canceration. No local recurrence occurred until the last follow up. No severe complications such as dyspnea and hemorrhage occured.
  
  
  CONCLUSIONS
  CO2 laser surgery is an effective and minimally invasive treatment for precancerous laryngeal lesions. Through selecting the appropriate patient and paying attention to the operation during surgery, the adhesion of vocal cord can be reduced or even be avoided after CO2 laser surgery.
authors.forename: Qingjia
authors.initials: Q
authors.lastname: Gu
authors.forename: Yong
authors.initials: Y
authors.lastname: Feng
authors.forename: Xiaoxu
authors.initials: X
authors.lastname: Yu
authors.forename: Jian'gang
authors.initials: J
authors.lastname: Fan
authors.forename: Debing
authors.initials: D
authors.lastname: Li
authors.forename: Gang
authors.initials: G
authors.lastname: He
mesh_terms: D000328:Adult; D000368:Aged; D002245:Carbon Dioxide / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods; D053685:Laser Therapy; D054020:Lasers, Gas / Q000627:therapeutic use; D008297:Male; D008866:Microsurgery; D008875:Middle Aged; D011230:Precancerous Conditions / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D002245:Carbon Dioxide