title: Different reconstruction techniques after pancreatoduodenectomy do not affect clinical and patient reported outcomes.
abstract: OBJECTIVE
  To evaluate the quality of life in a 2-year follow-up study in consecutive subjects who underwent pancreaticoduodenectomy with different reconstruction techniques: pancreaticojejunostomy or pancreaticogastrostomy.
  
  
  METHODS
  One hundred and ninety-seven consecutive patients were studied: 164 (83.2%) had malignant and 33 (16.8%) had benign disease. The EORTC QLQ-C30 questionnaire was administered at 5 different time points for evaluation: before surgery, and 6, 12, 18 and 24 months after discharge.
  
  
  RESULTS
  Pancreaticojejunostomy was performed in 189 patients (95.9%) and pancreaticogastrostomy in 8 patients (4.1%). In the follow-up evaluation, the quality of life significantly improved using the various surgical approaches; improvement over time was not significantly different among the various reconstruction techniques.
  
  
  CONCLUSIONS
  In clinical practice, different surgical reconstruction techniques are equally effective in improving the quality of life after pancreaticoduodenectomy.
authors.affiliation: Department of Digestive Diseases and Internal Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy. Electronic address: raffaele.pezzilli@aosp.bo.it.
authors.forename: Raffaele
authors.initials: R
authors.lastname: Pezzilli
authors.affiliation: Department of Surgery, GB Rossi Hospital, University of Verona, Verona, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Falconi
authors.affiliation: Department of Pancreatic Surgery, S. Raffaele Hospital, Milan, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Zerbi
authors.affiliation: Department of General Surgery, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Casadei
authors.affiliation: Department of Digestive Diseases and Internal Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
authors.forename: Antonio M
authors.initials: AM
authors.lastname: Morselli-Labate
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007558:Italy / Q000453:epidemiology; D007583:Jejunum / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000601:surgery; D016577:Pancreaticoduodenectomy / Q000009:adverse effects*; D011183:Postoperative Complications / Q000453:epidemiology / Q000517:prevention & control*; D011446:Prospective Studies; D011788:Quality of Life; D019651:Plastic Surgery Procedures / Q000009:adverse effects*; D013270:Stomach / Q000601:surgery; D054047:Surgical Stomas / Q000009:adverse effects*; D055815:Young Adult
keywords: Chronic pancreatitis; Diagnosis; Disease management; Pancreatic neoplasms; Patient reported outcome