title: Cardiovascular risk factors and cardiovascular diseases in patients with moderate to severe psoriasis under systemic treatment. PSO-RISK, descriptive study.
abstract: BACKGROUND
  The prevalence of cardiovascular risk factors (CVRF) in psoriasis has not been studied in large Spanish samples.
  
  
  OBJECTIVE
  To assess the prevalence of major CVRFs in psoriasis patients requiring systemic treatments.
  
  
  METHODS
  Cross-sectional study in psoriasis patients from 33 hospital dermatology offices throughout Spain. Blood pressure (BP) was measured and a fasting lab test was performed. Each CVRF was diagnosed according to the recommendations of international societies.
  
  
  RESULTS
  In 368 patients (mean age 48 years old, 36% women), 80.2% had at least one CVRF. The prevalence of each CVRF was similar in men and women and slightly higher in patients with psoriatic arthritis and in patients with a history of more severe disease. The percentage of patients treated with drugs to control CVRF was low (∼ 50% of those with each CVRF). A total of 20.7% had experienced some cardiovascular disease (CVD) episode.
  
  
  CONCLUSIONS
  The prevalence of CVRF was high, higher than in the general Spanish population, and 20% had already suffered CVD. However, the percentage with drug treatments for CVRF was low.
authors.affiliation: Dpt Dermatology, Hospital 12 de Octubre, Av de Córdoba, s/n, 28041 Madrid, Spain.
authors.forename: Francisco
authors.initials: F
authors.lastname: Vanaclocha
authors.affiliation: Dpt Dermatology, Hospital General Universitario, Alicante, Spain.
authors.forename: Isabel
authors.initials: I
authors.lastname: Belinchón
authors.affiliation: Dpt of Dermatology, Hospital General Universitario, Valencia, Spain.
authors.forename: José L
authors.initials: JL
authors.lastname: Sánchez-Carazo
authors.affiliation: Dpt Dermatology, Hospital 12 de Octubre, Av de Córdoba, s/n, 28041 Madrid, Spain.
authors.forename: Raquel
authors.initials: R
authors.lastname: Rivera
authors.affiliation: Dpt of Dermatology, Hospital Germans Trias i Pujol, Badalona, Spain.
authors.forename: José M
authors.initials: JM
authors.lastname: Carrascosa
authors.affiliation: Medical Affairs, Merck Sharp & Dohme of Spain, Josefa Valcárcel 38, 28027 Madrid, Spain.
authors.forename: Luis
authors.initials: L
authors.lastname: Cea-Calvo
authors.affiliation: Medical Affairs, Merck Sharp & Dohme of Spain, Josefa Valcárcel 38, 28027 Madrid, Spain.
authors.forename: Berta
authors.initials: B
authors.lastname: Juliá
authors.affiliation: Dpt of Dermatology, Hospital de la St Creu i S Pau, Barcelona, Spain.
authors.forename: Lluìs
authors.initials: L
authors.lastname: Puig
mesh_terms: D000328:Adult; D000367:Age Factors; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000453:epidemiology; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000188:drug therapy / Q000453:epidemiology; D006973:Hypertension / Q000188:drug therapy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology; D015995:Prevalence; D011565:Psoriasis / Q000188:drug therapy / Q000453:epidemiology*; D012307:Risk Factors; D057185:Sedentary Behavior; D012720:Severity of Illness Index; D012737:Sex Factors; D012907:Smoking / Q000453:epidemiology; D013030:Spain / Q000453:epidemiology
keywords: cardiovascular disease; cardiovascular risk factors; prevalence; psoriasis