title: Histiocytic sarcoma with acute lymphoblastic leukemia a rare association: case report and literature review.
abstract: Definition and diagnostic criteria for histiocytic sarcoma (HS) have changed over last two decades due to available new immunohistochemical markers, as well as better understanding of the biology of disease. We report here a case of 4 years old boy diagnosed as acute lymphoblastic leukemia (ALL), who later developed HS of pleura, when he was on maintenance phase of ALL protocol. HS constitutes less than 1 % of the haematolymphoid neoplasm, even more rare is association of HS with ALL. Thus reporting here a rare association of HS with ALL, will help in knowing the actual incidence of HS as well as association with ALL.
authors.affiliation: Department of Haematology, Christian Medical College and Hospital, Ida Scudder Road, Vellore, 632004 Tamil Nadu India.
authors.forename: Abhijeet P
authors.initials: AP
authors.lastname: Ganapule
authors.affiliation: Department of Pathology, Christian Medical College and Hospital, Ida Scudder Road, Vellore, 632004 Tamil Nadu India.
authors.forename: Mayank
authors.initials: M
authors.lastname: Gupta
authors.affiliation: Department of Pathology, Christian Medical College and Hospital, Ida Scudder Road, Vellore, 632004 Tamil Nadu India.
authors.forename: Gautami
authors.initials: G
authors.lastname: Kokil
authors.affiliation: Department of Haematology, Christian Medical College and Hospital, Ida Scudder Road, Vellore, 632004 Tamil Nadu India.
authors.forename: Auro
authors.initials: A
authors.lastname: Viswabandya
keywords: Acute lymphoblastic leukemia (ALL); Haematolymphoid Neoplasm; Histiocytic sarcoma (HS)