title: Variant morphology in multiple myeloma.
abstract: A 45-year-old man presented to the clinic with the chief complaints of low back pain, marked weight loss, and pallor of 2 months duration. He was found to have severe normocytic anemia with leukoerythroblastosis. Bone marrow aspirate resulted in a dry tap. Marrow trephine biopsy showed findings initially interpreted as poorly differentiated carcinoma involving marrow. Immunohistochemistry and protein studies established a diagnosis of IgG Kappa multiple myeloma. Correlation of marrow biopsy findings with clinical, radiological and immunological data remain an essential part of the diagnostic evaluation of multiple myeloma.
authors.affiliation: The Department of Medicine, Medicity Hospitals, 5-9-22 Secretariat Road, Hyderabad, 500063 India.
authors.forename: Prasad R
authors.initials: PR
authors.lastname: Koduri
authors.affiliation: Department of Pathology, Apollo Hospital, Hyderabad, India.
authors.forename: Swarnalata
authors.initials: S
authors.lastname: Gowrishankar
authors.affiliation: Department of Radiation Oncology, MNJ Cancer Hospital, Hyderabad, India.
authors.forename: Vijay Kumar
authors.initials: VK
authors.lastname: Malladi
keywords: Bone marrow morphology; Carcinoma; Myeloma