title: An efficient generation method and remarkable reactivities of 3-triflyloxybenzyne.
abstract: 3-Triflyloxybenzyne was generated via an iodine-magnesium exchange reaction of 1,3-bis(triflyloxy)-2-iodobenzene using the trimethylsilylmethyl Grignard reagent. Various arynophiles and nucleophiles reacted regioselectively with 3-triflyoxybenzyne to afford cycloadducts and unique aryl triflones, which were provided via thia-Fries rearrangement.
authors.affiliation: Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan. thosoya.cb@tmd.ac.jp.
authors.forename: Suguru
authors.initials: S
authors.lastname: Yoshida
authors.forename: Keisuke
authors.initials: K
authors.lastname: Uchida
authors.forename: Kazunobu
authors.initials: K
authors.lastname: Igawa
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Tomooka
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Hosoya
mesh_terms: D001555:Benzene Derivatives / Q000138:chemical synthesis* / Q000737:chemistry*; D061565:Cycloaddition Reaction; D007455:Iodine / Q000737:chemistry; D008274:Magnesium / Q000737:chemistry
chemical_list: D001555:Benzene Derivatives; D007455:Iodine; D008274:Magnesium