title: [Pregnancy jeopardized by pseudoxanthoma elasticum].
abstract: Pseudoxanthoma elasticum (PXE) is a rare inherited systemic disorder characterized by progressive calcification in the elastic tissue. Information about pregnancy in women with PXE is sparse. We report of a 36-year-old Caucasian woman, diagnosed with PXE, with a dichorionic diamniotic twin pregnancy, whose antenatal ultrasound scans showed a hyperechogenic placenta due to calcification. The calcification was confirmed on post-partum placental histology. Both twins, delivered via caesarean section due to maternal bleeding at 27 weeks of gestation suffered from intraventricular haemorrhage.
authors.affiliation: Gynækologisk Obstetrisk Afdeling, Sygehus Lillebælt, Skovvangen 2-8, 6000 Kolding. E-mail: henrik.christian.drue1@rsyd.dk.
authors.forename: Henrik Christian
authors.initials: HC
authors.lastname: Drue
authors.forename: Helle
authors.initials: H
authors.lastname: Mogensen
authors.forename: Annette Wind
authors.initials: AW
authors.lastname: Olesen
mesh_terms: D000328:Adult; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000209:etiology*; D002543:Cerebral Hemorrhage / Q000209:etiology; D002585:Cesarean Section; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology; D007231:Infant, Newborn; D066087:Perinatal Death; D010922:Placenta Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D011247:Pregnancy; D059285:Pregnancy, Twin; D011561:Pseudoxanthoma Elasticum / Q000150:complications*; D016216:Ultrasonography, Prenatal