title: [Unmet needs in the treatment of type 2 diabetes].
abstract: Type 2 diabetes represents one of the most important health problems, provided due to its high prevalence and significant morbi-mortality. At present time, we know that an intensive control of all cardiovascular risk factors from the beginning prevents the appearance and progression of micro and macrovascular complications. Nevertheless, only few patients achieve the degree of metabolic control recommended by diabetes therapeutic guidelines. This is due to different reasons such as lack of patients compliance and therapeutic inertia by doctors. Also, the available therapeutic approaches are limited. We still do not have the ideal antidiabetic drug, which should be able to be used in all phases of the disease, have sustained durability, be well tolerated not inducing hypoglycaemia, and promote weight loss, cardiovascular protection and reducing morbi-mortality at a low cost. The launching of new drugs with attractive mechanisms of action and few side effects may help to achieve these goals, though we still should wait for the results of studies demonstrating their effect on cardiovascular endpoints.
authors.affiliation: Profesor Titular, Departamento Medicina, Universidad de Oviedo. Hospital Universitario Central de Asturias, Oviedo, España. Electronic address: delgadoelias@uniovi.es.
authors.forename: Elías
authors.initials: E
authors.lastname: Delgado
mesh_terms: D002318:Cardiovascular Diseases / Q000209:etiology / Q000401:mortality / Q000517:prevention & control; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000188:drug therapy* / Q000401:mortality; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D012307:Risk Factors; D015431:Weight Loss
chemical_list: D007004:Hypoglycemic Agents
keywords: Antidiabéticos orales; Control glucémico; Glucose control; Inercia terapéutica; Oral antidiabetic drugs; Prioridad en el tratamiento; Therapeutic inertia; Treatment priority