title: Endobronchial valve placement as destination therapy for recurrent pneumothorax in the setting of advanced malignancy.
abstract: The development of a persistent air leak after pneumothorax can be encountered in patients with underlying structural lung disease. In those with advanced malignancy or other comorbidities, the ability to tolerate general anesthesia and thoracoscopic procedures may limit definitive management. We describe the case of a 68-y-old male with refractory acute myelogenous leukemia presenting with recurrent secondary spontaneous pneumothorax and persistent air leak related to an underlying fungal pneumonia. Endobronchial valve placement allowed for timely chest tube removal and discharge from the hospital, as well as avoidance of a thoracoscopic procedure and pleurodesis.
authors.affiliation: Division of Pulmonary, Allergy, and Critical Care Medicine cgilbert1@hmc.psu.edu.
authors.forename: Christopher R
authors.initials: CR
authors.lastname: Gilbert
authors.affiliation: Division of Pulmonary, Allergy, and Critical Care Medicine.
authors.forename: Jennifer W
authors.initials: JW
authors.lastname: Toth
authors.affiliation: Division of Pulmonary, Allergy, and Critical Care Medicine.
authors.forename: Umar
authors.initials: U
authors.lastname: Osman
authors.affiliation: Division of Thoracic Surgery, Milton S Hershey Medical Center, Penn State College of Medicine, Hershey, Pennsylvania.
authors.forename: Michael F
authors.initials: MF
authors.lastname: Reed
mesh_terms: D001980:Bronchi / Q000601:surgery*; D001999:Bronchoscopy / Q000379:methods*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000175:diagnosis; D008297:Male; D011030:Pneumothorax / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D019736:Prostheses and Implants; D012008:Recurrence; D014057:Tomography, X-Ray Computed
keywords: destination therapy; endobronchial valve; persistent air leak; pneumothorax