title: [Analysis of fragments of intergenome spacers of human body observed in chromosomes containing no nuclear organization].
abstract: Tandem repetitions of rDNA provide so-called nuclear organizations (NOR). On the other hand, rDNA-structures are observed in some NOR chromosomes. It was demonstrated that, in addition to ribosome biogenesis, nucleoli provided a number of functions: cell cycle regulation, stress-induced response, transcription regulation, which often induced cell cascades. The mechanisms of the induction of rDNA segments in NOR chromosomes are obscure and require further research. About 1/3 repetitions are associated with nucleoli and SINE/Alu repetitions, homogeneous repetition, and tandem repetition. Perhaps, relative position of nucleoli and chromosomes may facilitate/prevent interaction of chromosomes with rDNA clusters. The variability of two larger repetitions in the central part of rMGS, LR1, and LR2 similar by -90% and separated by several hundred pairs of bases from each other was studied in our previous works. This work was devoted to the search for the LR1-LR2 segments in other chromosomes, characterization of their terminal tips at rupture points and genome areas of incorporation of the LR1-LR2 segments.
authors.forename: N S
authors.initials: NS
authors.lastname: Kupriyanova
authors.forename: K K
authors.initials: KK
authors.lastname: Nechvolodov
authors.forename: A V
authors.initials: AV
authors.lastname: Korsunenko
mesh_terms: D020087:Alu Elements; D001483:Base Sequence; D002877:Chromosomes, Human / Q000737:chemistry* / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D015894:Genome, Human; D006801:Humans; D008969:Molecular Sequence Data; D009697:Nucleolus Organizer Region / Q000737:chemistry* / Q000235:genetics
chemical_list: D004275:DNA, Ribosomal