title: Relation of joint spectral and time domain optical coherence tomography (jSTdOCT) and phase-resolved Doppler OCT.
abstract: A variety of promising approaches for quantitative flow velocity measurement in OCT have been proposed in recent years. The question is: Which method gets the most precise flow velocity out of the interference signals detected. We have compared the promising joint spectral and time domain optical coherence tomography (jSTdOCT) and the commonly used phase-resolved Doppler OCT (DOCT) and describe the link between these two proven methods for OCT in the Fourier domain (FD OCT). First, we show that jSTdOCT can be significantly improved by calculating the center of gravity via an unbiased complex algorithm instead of detecting the maximum intensity signal of the broadened Doppler frequency spectrum. Secondly, we introduce a unified mathematical description for DOCT and jSTdOCT that differs only in one exponent and call it enhjSTdOCT. Third, we present that enhjSTdOCT has the potential to significantly reduce the noise of the velocity measurement by choosing an exponent depending on the transverse sample velocity component and the signal-to-noise ratio. EnhjSTdOCT is verified numerically and experimentally to find the optimal parameters for maximal velocity noise reduction.
authors.forename: Julia
authors.initials: J
authors.lastname: Walther
authors.forename: Edmund
authors.initials: E
authors.lastname: Koch
mesh_terms: D000465:Algorithms; D001783:Blood Flow Velocity / Q000502:physiology*; D005583:Fourier Analysis; D006801:Humans; D012171:Retinal Vessels / Q000166:cytology* / Q000502:physiology; D059629:Signal-To-Noise Ratio; D041623:Tomography, Optical Coherence / Q000379:methods*