title: Chronic respiratory failure due to toxic epidermal necrosis in a 10 year old girl.
abstract: Toxic epidermal necrosis is a severe mucocutaneous disease with a high mortality rate. A third of the patients surviving the acute phase will develop pulmonary complications. The most frequent complication is bronchiolitis obliterans. Despite well-conducted treatment, in most cases, lung injury often leads to chronic respiratory failure. We describe here the case of a young patient that presented a toxic epidermal necrosis at the age of 3 years. Poor therapeutic compliance result in chronic respiratory failure and after 7 years of follow-up, pulmonary transplant remains the only long-term alternative. Close monitoring of respiratory symptoms in the course of toxic epidermal necrosis, intense treatment as soon as they appear and a long-term follow-up are essential to postpone chronic respiratory failure.
authors.forename: M
authors.initials: M
authors.lastname: Thimmesch
authors.forename: A
authors.initials: A
authors.lastname: Gilbert
authors.forename: D
authors.initials: D
authors.lastname: Tuerlinckx
authors.forename: E
authors.initials: E
authors.lastname: Bodart
mesh_terms: D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D006801:Humans; D012131:Respiratory Insufficiency / Q000209:etiology*; D013262:Stevens-Johnson Syndrome / Q000150:complications*
keywords: Bronchiolitis obliterans; Chronic respiratory failure,; Pulmonary transplant,; Toxic epidermal necrosis,