title: Invasive lung infection by Scedosporium apiospermum in an immunocompetent individual.
abstract: Scedosporium apiospermum previously known as Monospermum apiospermum is a ubiquitous fungus found in soil, polluted water and sewage. It causes broad spectrum of diseases, including soft tissue infections, septic arthritis, osteomyelitis, ophthalmic infections, sinusitis, pneumonia, meningitis, brain abscesses, endocarditis and disseminated infection. In recent years, it has been shown to be pathogenic for both immunocompetent and immunosuppressed patients. It is a significant opportunist with very high levels of antifungal resistance. We report here a case of invasive lung infection due to S. apiospermum in an immunocompetent patient who responded to antifungal therapy and surgical treatment.
authors.affiliation: Department of Microbiology, Madras Medical College, Chennai, Tamil Nadu, India.
authors.forename: David
authors.initials: D
authors.lastname: Agatha
authors.forename: Krishnan Usha
authors.initials: KU
authors.lastname: Krishnan
authors.forename: Ved-achalam
authors.initials: VA
authors.lastname: Dillirani
authors.forename: Rangam
authors.initials: R
authors.lastname: Selvi
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use*; D025141:Drug Resistance, Fungal; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008168:Lung / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology; D008172:Lung Diseases, Fungal / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery*; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D016533:Mycological Typing Techniques; D011859:Radiography; D021681:Scedosporium / Q000187:drug effects*
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B