title: Advances in molecular genetic studies of attention deficit hyperactivity disorder in China.
abstract: Attention deficit hyperactivity disorder (ADHD) is a common psychiatric condition in children worldwide that typically includes a combination of symptoms of inattention and hyperactivity/impulsivity. Genetic factors are believed to be important in the development and course of ADHD so many candidate genes studies and genome-wide association studies (GWAS) have been conducted in search of the genetic mechanisms that cause or influence the condition. This review provides an overview of gene association and pharmacogenetic studies of ADHD from mainland China and elsewhere that use Han Chinese samples. To date, studies from China and elsewhere remain inconclusive so future studies need to consider alternative analytic techniques and test new biological hypotheses about the relationship of neurotransmission and neurodevelopment to the onset and course of this disabling condition.
authors.affiliation: Peking University Sixth Hospital Institute of Mental Health, Beijing, China ; Key Laboratory of Mental Health, Ministry of Health, Peking University, Beijing, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Gao
authors.affiliation: Peking University Sixth Hospital Institute of Mental Health, Beijing, China ; Key Laboratory of Mental Health, Ministry of Health, Peking University, Beijing, China.
authors.forename: Lu
authors.initials: L
authors.lastname: Liu
authors.affiliation: Peking University Sixth Hospital Institute of Mental Health, Beijing, China ; Key Laboratory of Mental Health, Ministry of Health, Peking University, Beijing, China.
authors.forename: Qiujin
authors.initials: Q
authors.lastname: Qian
authors.affiliation: Peking University Sixth Hospital Institute of Mental Health, Beijing, China ; Key Laboratory of Mental Health, Ministry of Health, Peking University, Beijing, China.
authors.forename: Yufeng
authors.initials: Y
authors.lastname: Wang
keywords: ADHD; China; GWAS; candidate gene studies; genetics