title: Adapted automated peritoneal dialysis.
abstract: Conventional automated peritoneal dialysis (APD) is prescribed as a repetition of the same dwell time and the same fill volume delivered by the cycler during the dialysis session. Nevertheless, it is well recognized that a cycle with a short dwell time and a small fill volume favors ultrafiltration (UF), while a cycle with a long dwell time and a large fill volume favors uremic toxin removal. The use of varied dwell times and dwell volumes, called adapted APD, allows for an optimized peritoneal dialysis prescription with better volume control--that is, both an increased UF volume at a lower metabolic cost [UF per gram of glucose absorbed (mL/g)] and increased dialytic sodium removal resulting in improved removal of uremic toxins (urea, creatinine, phosphate) during dialysis.
authors.forename: Michel
authors.initials: M
authors.lastname: Fischbach
authors.forename: Ariane
authors.initials: A
authors.lastname: Zaloszyc
authors.forename: Betti
authors.initials: B
authors.lastname: Schaefer
authors.forename: Claus
authors.initials: C
authors.lastname: Schmitt
mesh_terms: D006801:Humans; D010530:Peritoneal Dialysis / Q000379:methods*; D019095:Point-of-Care Systems