title: Rodent Models and Behavioral Outcomes of Cervical Spinal Cord Injury.
abstract: Rodent spinal cord injury (SCI) models have been developed to examine functional and physiological deficits after spinal cord injury with the hope that these models will elucidate information about human SCI. Models are needed to examine possible treatments and to understand histopathology after SCI; however, they should be considered carefully and chosen based on the goals of the study being performed. Contusion, compression, transection, and other models exist and have the potential to reveal important information about SCI that may be related to human SCI and the outcomes of treatment and timing of intervention.
authors.affiliation: Department of Biomedical Engineering, The University of Texas, Austin, TX, USA.
authors.forename: Sydney A
authors.initials: SA
authors.lastname: Geissler
authors.affiliation: Department of Biomedical Engineering, The University of Texas, Austin, TX, USA ; Professor, J Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA.
authors.forename: Christine E
authors.initials: CE
authors.lastname: Schmidt
authors.affiliation: Professor, Department of Psychology, The University of Texas, Austin, TX, USA ; Professor, Department of Neuroscience, The University of Texas, Austin, TX, USA.
authors.forename: Timothy
authors.initials: T
authors.lastname: Schallert
keywords: Behavioral assessment; Behavioral deficit; Cervical spinal cord injury; Forelimb function; Functional recovery; Regeneration; Rodent models; Spinal cord injury surgical models