title: Fly piRNA biogenesis: tap dancing with Tej.
abstract: Piwi-interacting RNAs (piRNAs) protect animal germlines from the deleterious effects of transposon activity. Unlike other small RNA classes like microRNAs (miRNAs) and small interfering RNAs (siRNAs), an exceptionally large number of factors are implicated in the biogenesis of piRNAs. Kai et al. have now added another one to this growing list, which we discuss in the overall context of our current knowledge of the piRNA biogenesis pathway in the Drosophila ovarian germline. See research article: http://www.biomedcentral.com/1741-7007/12/61.
authors.forename: Zhaolin
authors.initials: Z
authors.lastname: Yang
authors.affiliation: European Molecular Biology Laboratory, Grenoble Outstation, University Grenoble Alpes-EMBL-CNRS, 71 avenue des Martyrs, Grenoble 38042, France. pillai@embl.fr.
authors.forename: Ramesh S
authors.initials: RS
authors.lastname: Pillai
mesh_terms: D000818:Animals; D029721:Drosophila Proteins / Q000235:genetics*; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D005854:Germ Cells / Q000166:cytology*; D009479:Neuropeptides / Q000235:genetics*; D034741:RNA, Small Interfering / Q000235:genetics*; D018626:Retroelements; D014157:Transcription Factors / Q000235:genetics*
chemical_list: D029721:Drosophila Proteins; D009479:Neuropeptides; D034741:RNA, Small Interfering; D018626:Retroelements; D014157:Transcription Factors