title: Kikuchi- Fujimoto disease of mesenteric lymph nodes mimicking acute appendicitis.
abstract: Kikuchi-Fujimoto disease, or histiocytic necrotising lymphadenopathy of unknown aetiology, is a rare, benign and self-limiting cause of lymphadenopathy often involving the cervical nodes, and rarely presenting with mesenteric lymphadenopathy. We present a 26-year-old Caucasian male, who presented with right iliac fossa pain and low grade pyrexia, mimicking acute appendicitis. He underwent a laparatomy and an extended right hemi-colectomy for a caecal mass. Histology of the specimen showed lymph nodes with extensive areas of necrosis, with abnormal architecture suggesting Kikuchi-Fujimoto lymphadenopathy. This was further confirmed by immunohistochemistry. In this context maintenance of a high index of suspicion of this condition can avoid major surgical interventions. We describe the management of our case of Kikuchi-Fujimoto's disease involving the mesenteric nodes and provide an up to date review of the pertinent literature on this subject.
authors.affiliation: Department of Surgery, Manchester Royal Infirmary, Oxford Road, Manchester, M13 9WL.
authors.forename: Anne
authors.initials: A
authors.lastname: Shrestha
authors.affiliation: Department of Surgery, Manchester Royal Infirmary, Oxford Road, Manchester, M13 9WL.
authors.forename: Katie
authors.initials: K
authors.lastname: Newton
authors.affiliation: Department of Surgery, Manchester Royal Infirmary, Oxford Road, Manchester, M13 9WL.
authors.forename: Emyr
authors.initials: E
authors.lastname: Benbow
authors.affiliation: Department of Surgery, Manchester Royal Infirmary, Oxford Road, Manchester, M13 9WL.
authors.forename: Rajeev
authors.initials: R
authors.lastname: Kushwaha
mesh_terms: D000328:Adult; D001064:Appendicitis / Q000175:diagnosis*; D003937:Diagnosis, Differential; D020042:Histiocytic Necrotizing Lymphadenitis / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008297:Male; D008640:Mesenteric Lymphadenitis / Q000175:diagnosis* / Q000601:surgery