title: Evaluation of femtosecond laser-assisted and manual clear corneal incisions and their effect on surgically induced astigmatism and higher-order aberrations.
abstract: OBJECTIVE
  To evaluate femtosecond laser-assisted and manual clear corneal incisions and their effect on surgically induced astigmatism (SIA) and corneal higher-order aberrations (HOAs).
  
  
  METHODS
  In a prospective randomized study, conventional phacoemulsification with a 2.8-mm clear corneal incision using a disposable keratome was performed in 20 eyes of 20 patients (manual group), and femtosecond laser-assisted cataract surgery with a 2.8-mm biplanar clear corneal tunnel created by a femtosecond laser (LenSx; Alcon Laboratories, Inc., Aliso Viejo, CA) was performed in 20 eyes of 20 patients (femtosecond laser group). Corneal topography readings and corneal wavefront aberrations (diameter: 9.0 mm) were obtained using a Scheimpflug camera (Pentacam HR; Oculus Optikgerate, Wetzlar, Germany) preoperatively and 3 months postoperatively.
  
  
  RESULTS
  There was no significant difference in SIA between the groups (femtosecond laser group: 0.47 ± 0.13 vs manual group: 0.41 ± 0.14; P = .218), but the axis deviation of the SIA axis from the previously planned axis was significantly smaller in the femtosecond laser group compared to the manual group (4.47°± 2.59° vs 7.38°± 4.72°, respectively; P = .048). Corneal HOAs increased significantly in both groups (femtosecond laser group: 0.13 ± 0.09 to 0.18 ± 0.12, P = .025; manual group: 0.13 ± 0.05 to 0.15 ± 0.05, P = .002), but preoperative and postoperative values did not differ significantly between them (P = .472 and .078, respectively). Lower-order and total corneal aberration values remained stable in both groups (P > .05).
  
  
  CONCLUSIONS
  There was no difference in SIA and induced HOAs between manual and femtosecond laser-created clear corneal incisions.
authors.forename: Zoltán Z
authors.initials: ZZ
authors.lastname: Nagy
authors.forename: Arpád
authors.initials: A
authors.lastname: Dunai
authors.forename: Kinga
authors.initials: K
authors.lastname: Kránitz
authors.forename: Agnes Ildikó
authors.initials: AI
authors.lastname: Takács
authors.forename: Gábor László
authors.initials: GL
authors.lastname: Sándor
authors.forename: Réka
authors.initials: R
authors.lastname: Hécz
authors.forename: Michael C
authors.initials: MC
authors.lastname: Knorz
mesh_terms: D000368:Aged; D001251:Astigmatism / Q000175:diagnosis / Q000209:etiology*; D003315:Cornea / Q000601:surgery*; D048988:Corneal Surgery, Laser / Q000009:adverse effects*; D019781:Corneal Topography; D057108:Corneal Wavefront Aberration / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular / Q000379:methods*; D008297:Male; D008875:Middle Aged; D013508:Ophthalmologic Surgical Procedures / Q000009:adverse effects*; D018918:Phacoemulsification / Q000379:methods*; D011446:Prospective Studies