title: Flow update for the carbonylation of 1-silyl-substituted organolithiums under CO pressure.
abstract: The generation of, and subsequent reactions with, 1-silyl-substituted organolithiums with CO was carried out using serially connected flow microreactors. The flow system proved to be quite useful for the carbonylation of silyl-substituted organolithiums under slightly pressurized conditions of CO, which was created conveniently by the use of a back-pressure regulator. This flow system, coupled with heating, accelerated the carbonylation reaction of 1-silyl-substituted organolithiums and allowed the stable silyl-substituted alkyllithium, 1,3-disilylallyllithium, which was not effective in a batch-flask reaction under a CO atmosphere, to participate in an efficient carbonylation reaction.
authors.affiliation: Department of Chemistry, Graduate School of Science, Osaka Prefecture University , Sakai, Osaka 599-8531, Japan.
authors.forename: Takahide
authors.initials: T
authors.lastname: Fukuyama
authors.forename: Takenori
authors.initials: T
authors.lastname: Totoki
authors.forename: Ilhyong
authors.initials: I
authors.lastname: Ryu