title: Evaluation of corneal biomechanical properties modification after small incision lenticule extraction using Scheimpflug-based noncontact tonometer.
abstract: OBJECTIVE
  To quantify the effect of small incision lenticule extraction (SMILE) on the corneal biomechanics using Scheimpflug noncontact tonometer (Corvis ST).
  
  
  METHODS
  Twenty eyes of twenty patients, evaluated as eligible for surgery, with high myopia and/or moderate myopic astigmatism, underwent small incision lenticule extraction (SMILE). All patients underwent Corvis ST preoperatively and postoperatively after 1 week, and 1 and 3 months to observe alterations of corneal biomechanical properties. The main outcome measures were Deformation Amplitude, 1st-AT, and 2nd-AT. The relationship between the amount of stroma removed and the percentage variation of the measured parameters from baseline was evaluated with generalized linear model from each time point. For completeness also intraocular pressure (IOP), central corneal thickness (CCT), and their variations after surgery were evaluated.
  
  
  RESULTS
  The ratio between the amount of removed refractive error and, respectively, changes of Deformation Amplitude, 1st-AT, and 2nd-AT were significantly modified at the 1st week after surgery (P = 0.005; P = 0.001; P = 0.024). At 1 and 3 months these values did not show statistically significant alterations. Intraocular pressure and central corneal thickness showed statistically significant changes during follow-up.
  
  
  CONCLUSIONS
  No significant modifications in biomechanical properties were observed after SMILE so this procedure could induce only minimal transient alterations of corneal biomechanics.
authors.affiliation: Ophthalmic Clinic, University "G d'Annunzio" of Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy.
authors.forename: Leonardo
authors.identifier: 0000-0003-4890-3834
authors.initials: L
authors.lastname: Mastropasqua
authors.affiliation: Ophthalmic Clinic, University "G d'Annunzio" of Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy.
authors.forename: Roberta
authors.initials: R
authors.lastname: Calienno
authors.affiliation: Ophthalmic Clinic, University "G d'Annunzio" of Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy.
authors.forename: Manuela
authors.initials: M
authors.lastname: Lanzini
authors.affiliation: Ophthalmic Clinic, University "G d'Annunzio" of Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy.
authors.forename: Martina
authors.initials: M
authors.lastname: Colasante
authors.affiliation: Ophthalmic Clinic, Campus Biomedico, University of Rome, 00185 Rome, Italy.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Mastropasqua
authors.affiliation: Ophthalmic Clinic, University "G d'Annunzio" of Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy.
authors.forename: Peter A
authors.initials: PA
authors.lastname: Mattei
authors.affiliation: Ophthalmic Clinic, University "G d'Annunzio" of Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Nubile
mesh_terms: D000328:Adult; D001696:Biomechanical Phenomena; D003315:Cornea / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery*; D063171:Corneal Pachymetry; D048988:Corneal Surgery, Laser / Q000379:methods*; D006801:Humans; D007429:Intraocular Pressure; D007834:Lasers; D008365:Manometry / Q000295:instrumentation*; D013997:Time Factors