title: Nutritional treatment in chronic kidney disease: the concept of nephroprotection.
abstract: Low-protein diets have been advocated for many decades as the cornerstone in the treatment of chronic kidney disease. Initially, the low intake of protein was used to reduce uremic symptoms; thereafter, albeit controversial, evidences suggested that dietary protein restriction can also slow the rate of progression of renal failure and the time until end-stage renal disease. This reviews focuses on the dietary factors and their influence on the loss of renal function and on the evidences in the literature supporting a nephroprotective role of the low-protein diet.
authors.affiliation: Unit of Nephrology, Federico II University of Naples, Naples, Italy, elyriccio@libero.it.
authors.forename: Eleonora
authors.initials: E
authors.lastname: Riccio
authors.forename: Antonella
authors.initials: A
authors.lastname: Di Nuzzi
authors.forename: Antonio
authors.initials: A
authors.lastname: Pisani
mesh_terms: D000818:Animals; D018753:Diet, Protein-Restricted; D004044:Dietary Proteins; D018450:Disease Progression; D005919:Glomerular Filtration Rate; D006801:Humans; D016226:Phosphorus, Dietary; D051436:Renal Insufficiency, Chronic / Q000178:diet therapy* / Q000503:physiopathology / Q000517:prevention & control; D012982:Sodium, Dietary
chemical_list: D004044:Dietary Proteins; D016226:Phosphorus, Dietary; D012982:Sodium, Dietary