title: Intra-abdominal inflammatory myofibroblastic tumor: spontaneous regression.
abstract: Inflammatory myofibroblastic tumors are usually treated by surgical resection. We herein report two cases of intra-abdominal inflammatory myofibroblastic tumors that were unresectable and underwent spontaneous regression without any treatment. Our case report and literature review show that regression is more common in the middle-aged and older male populations. Abdominal discomfort and fever were the most common symptoms, but the majority of patients had no obvious physical signs. There was no specific indicator for diagnosis. The majority of the lesions regressed within 3 mo and nearly all of the masses completely resolved within 1 year. We conclude that the clinical characteristics of inflammatory myofibroblastic tumors are variable and, accordingly, the disease needs to be subdivided and treated on an individual basis. Surgery is always the first-line treatment; however, for those masses assessed as unresectable, conservative therapy with intense follow-up should be considered.
authors.affiliation: Jun-Jie Zhao, Jia-Qian Ling, Yong Fang, Xiao-Dong Gao, Ping Shu, Kun-Tang Shen, Jing Qin, Yi-Hong Sun, Xin-Yu Qin, Department of General Surgery, Zhong Shan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Jun-Jie
authors.initials: JJ
authors.lastname: Zhao
authors.affiliation: Jun-Jie Zhao, Jia-Qian Ling, Yong Fang, Xiao-Dong Gao, Ping Shu, Kun-Tang Shen, Jing Qin, Yi-Hong Sun, Xin-Yu Qin, Department of General Surgery, Zhong Shan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Jia-Qian
authors.initials: JQ
authors.lastname: Ling
authors.affiliation: Jun-Jie Zhao, Jia-Qian Ling, Yong Fang, Xiao-Dong Gao, Ping Shu, Kun-Tang Shen, Jing Qin, Yi-Hong Sun, Xin-Yu Qin, Department of General Surgery, Zhong Shan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Fang
authors.affiliation: Jun-Jie Zhao, Jia-Qian Ling, Yong Fang, Xiao-Dong Gao, Ping Shu, Kun-Tang Shen, Jing Qin, Yi-Hong Sun, Xin-Yu Qin, Department of General Surgery, Zhong Shan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Xiao-Dong
authors.initials: XD
authors.lastname: Gao
authors.affiliation: Jun-Jie Zhao, Jia-Qian Ling, Yong Fang, Xiao-Dong Gao, Ping Shu, Kun-Tang Shen, Jing Qin, Yi-Hong Sun, Xin-Yu Qin, Department of General Surgery, Zhong Shan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Shu
authors.affiliation: Jun-Jie Zhao, Jia-Qian Ling, Yong Fang, Xiao-Dong Gao, Ping Shu, Kun-Tang Shen, Jing Qin, Yi-Hong Sun, Xin-Yu Qin, Department of General Surgery, Zhong Shan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Kun-Tang
authors.initials: KT
authors.lastname: Shen
authors.affiliation: Jun-Jie Zhao, Jia-Qian Ling, Yong Fang, Xiao-Dong Gao, Ping Shu, Kun-Tang Shen, Jing Qin, Yi-Hong Sun, Xin-Yu Qin, Department of General Surgery, Zhong Shan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Qin
authors.affiliation: Jun-Jie Zhao, Jia-Qian Ling, Yong Fang, Xiao-Dong Gao, Ping Shu, Kun-Tang Shen, Jing Qin, Yi-Hong Sun, Xin-Yu Qin, Department of General Surgery, Zhong Shan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Yi-Hong
authors.initials: YH
authors.lastname: Sun
authors.affiliation: Jun-Jie Zhao, Jia-Qian Ling, Yong Fang, Xiao-Dong Gao, Ping Shu, Kun-Tang Shen, Jing Qin, Yi-Hong Sun, Xin-Yu Qin, Department of General Surgery, Zhong Shan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Xin-Yu
authors.initials: XY
authors.lastname: Qin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D004066:Digestive System Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006104:Granuloma, Plasma Cell / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D058628:Myofibroblasts / Q000473:pathology*; D011237:Predictive Value of Tests; D012075:Remission, Spontaneous; D014057:Tomography, X-Ray Computed; D055815:Young Adult
keywords: Abdominal cavity; Inflammatory myofibroblastic tumor; Inflammatory pseudotumor; Spontaneous regression