title: Dual ovarian stimulation is a new viable option for enhancing the oocyte yield when the time for assisted reproductive technnology is limited.
abstract: Ovarian stimulation improves assisted reproductive technology outcome by increasing the number of oocytes available for insemination and in-vitro handling. A recent Duplex protocol features a dual stimulation, with the second stimulation started immediately after the first oocyte retrieval. Remarkably, the Duplex protocol is unexpectadly well tolerated by women and provides twice as many oocytes and embryos as a regular antagonist protocol in less than 30 days.
authors.affiliation: Dept of Ob Gyn and Reproductive Medicine, Paris Sorbonne Cité, Assistance Publique Hôpitaux de Paris, CHU Cochin, Université Paris Descartes, Paris, France.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Moffat
authors.affiliation: Dept of Ob Gyn and Reproductive Medicine, Paris Sorbonne Cité, Assistance Publique Hôpitaux de Paris, CHU Cochin, Université Paris Descartes, Paris, France.
authors.forename: Paul
authors.initials: P
authors.lastname: Pirtea
authors.affiliation: Dept of Ob Gyn and Reproductive Medicine, Paris Sorbonne Cité, Assistance Publique Hôpitaux de Paris, CHU Cochin, Université Paris Descartes, Paris, France.
authors.forename: Vanessa
authors.initials: V
authors.lastname: Gayet
authors.affiliation: Dept of Biology of Reproduction, Paris Sorbonne Cité, Assistance Publique Hôpitaux de Paris, CHU Cochin, Université Paris Descartes, Paris, France.
authors.forename: Jean Philippe
authors.initials: JP
authors.lastname: Wolf
authors.affiliation: Dept of Ob Gyn and Reproductive Medicine, Paris Sorbonne Cité, Assistance Publique Hôpitaux de Paris, CHU Cochin, Université Paris Descartes, Paris, France; Cochin Institute, CNRS UMR 8104, ISERM U1016, Paris, France.
authors.forename: Charles
authors.initials: C
authors.lastname: Chapron
authors.affiliation: Dept of Ob Gyn and Reproductive Medicine, Paris Sorbonne Cité, Assistance Publique Hôpitaux de Paris, CHU Cochin, Université Paris Descartes, Paris, France. Electronic address: ddeziegler@me.com.
authors.forename: Dominique
authors.initials: D
authors.lastname: de Ziegler
mesh_terms: D005260:Female; D005640:Follicle Stimulating Hormone / Q000008:administration & dosage / Q000378:metabolism*; D006801:Humans; D009865:Oocytes / Q000166:cytology / Q000502:physiology*; D010062:Ovulation Induction / Q000379:methods*; D027724:Reproductive Techniques, Assisted; D013997:Time Factors; D017329:Triptorelin Pamoate
chemical_list: D017329:Triptorelin Pamoate; D005640:Follicle Stimulating Hormone
keywords: ART; ovarian reserve; ovarian stimulation; poor responder