title: Newborns with congenital heart diseases: epidemiological data from a single reference center in Brazil.
abstract: OBJECTIVE
  to describe the epidemiological data of the population born with the diagnosis of Congenital Heart Disease (CHD); to compare diagnoses made using fetal echocardiography with the findings from postnatal echocardiography or anatomopathological examination of the heart; and to evaluate mortality among newborns that underwent surgical treatment.
  
  
  METHODS
  this was a cohort study with information gathered from the medical records of the pregnant women and their newborns diagnosed with CHD during the fetal or postnatal periods, between January 2008 and December 2012. Means, standard deviations and maximum and minimum values were calculated for the quantitative variables. Relative and absolute values were calculated for the qualitative variables. The heart malformations were categorized in four groups: complex lesions, significant lesions, minor lesions and others.
  
  
  RESULTS
  we detected postnatal incidence of CHD of 1.9% at our service. The mean maternal age was 28.3 years and 10 (21.3%) of the pregnant women were ≥ 35 years old. The mean gestational age at the time of performing the fetal echocardiogram was 27.8 weeks. Mean gestational age at delivery was 38 weeks, and the mean weight of the newborns was 2,644.5 grams. Regarding the diagnosis of CHD, there were: 23 complex lesions (39%); 15 significant lesions (26%); 10 minor lesions (17%); 4 other lesions (7%) and 6 normal anatomies (10%). The diagnosis of CHD made on the fetus and postnatally coincided in 77.6% of the cases. A total of 27 patients (60%) underwent surgery, and the outcome was neonatal death in five cases.
  
  
  CONCLUSIONS
  we detected postnatal incidence of CHD of 1.9%, and it was more common among older pregnant women and with late detection in the intrauterine period. Complex heart diseases predominated, thus making it difficult to have a good result regarding neonatal mortality rates.
authors.affiliation: Fetal Cardiology Unit, Department of Obstetrics, Federal University of São Paulo (UNIFESP), São Paulo-SP, Brazil.
authors.forename: Karina Peres
authors.initials: KP
authors.lastname: Silva
authors.affiliation: Fetal Cardiology Unit, Department of Obstetrics, Federal University of São Paulo (UNIFESP), São Paulo-SP, Brazil.
authors.forename: Luciane Alves
authors.initials: LA
authors.lastname: Rocha
authors.affiliation: Discipline of Neonatology, Department of Pediatrics, Federal University of São Paulo (UNIFESP), São Paulo-SP, Brazil.
authors.forename: Ana Teresa Figueiredo Stochero
authors.initials: AT
authors.lastname: Leslie
authors.affiliation: Discipline of Neonatology, Department of Pediatrics, Federal University of São Paulo (UNIFESP), São Paulo-SP, Brazil.
authors.forename: Ruth
authors.initials: R
authors.lastname: Guinsburg
authors.affiliation: Discipline of Cardiology, Department of Clinics, São Paulo Federal University (UNIFESP), São Paulo-SP, Brazil.
authors.forename: Célia Maria Camelo
authors.initials: CM
authors.lastname: Silva
authors.affiliation: Fetal Cardiology Unit, Department of Obstetrics, Federal University of São Paulo (UNIFESP), São Paulo-SP, Brazil.
authors.forename: Luciano Marcondes Machado
authors.initials: LM
authors.lastname: Nardozza
authors.affiliation: Fetal Cardiology Unit, Department of Obstetrics, Federal University of São Paulo (UNIFESP), São Paulo-SP, Brazil.
authors.forename: Antonio Fernandes
authors.initials: AF
authors.lastname: Moron
authors.affiliation: Fetal Cardiology Unit, Department of Obstetrics, Federal University of São Paulo (UNIFESP), São Paulo-SP, Brazil.
authors.forename: Edward
authors.initials: E
authors.lastname: Araujo Júnior
keywords: congenital heart diseases; echocardiography; newborn; prenatal diagnosis