title: Endurance training and the risk of bronchial asthma in female cross-country skiers.
abstract: Exercise is one of the crucial factors responsible for asthma development and exacerbation. The purpose of the present study was to assess the risk of bronchial asthma in female athletes. Spirometric evaluations and physical exercise test were performed and exhaled nitric oxide (eNO) levels were measured in 12 female elite cross-country skiers. Serum concentrations of interleukin 1 beta (IL-1β), tumor necrosis factor-alpha (TNF-α), and interleukin 6 (IL-6) were measured in all subjects before exercise, immediately after it, and after 15 min of recovery. Peak eNO values were 18.7±4.8 (ppb) and did not confirm the risk of early bronchial asthma symptoms. A graded exercise test caused significant increases in TNF-α and IL-1β concentration (p<0.05) after 15 min of recovery. A significant negative correlation was found between resting and post-exercise eNO and IL-6 levels (p<0.01). Our study did not confirm an increased risk of bronchial asthma or respiratory tract inflammatory conditions among female cross-country skiers exposed to physical exertion.
authors.affiliation: Department of Physiological and Medical Sciences, The Jerzy Kukuczka Academy of Physical Education, 72A, Mikołowska St., 40-065, Katowice, Poland, olazebrowska@yahoo.com.
authors.forename: A
authors.initials: A
authors.lastname: Żebrowska
authors.forename: B
authors.initials: B
authors.lastname: Głuchowska
authors.forename: D
authors.initials: D
authors.lastname: Jastrzębski
authors.forename: A
authors.initials: A
authors.lastname: Kochańska-Dziurowicz
authors.forename: A
authors.initials: A
authors.lastname: Stanjek-Cichoracka
authors.forename: I
authors.initials: I
authors.lastname: Pokora
mesh_terms: D001249:Asthma / Q000453:epidemiology / Q000503:physiopathology*; D056352:Athletes; D054874:Athletic Performance / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D009569:Nitric Oxide / Q000378:metabolism; D010807:Physical Endurance / Q000502:physiology*; D012307:Risk Factors; D012865:Skiing / Q000502:physiology*; D013147:Spirometry; D055815:Young Adult
chemical_list: D009569:Nitric Oxide