title: The chronic injury glucose error grid: a tool to reduce diabetes complications.
abstract: Traditional glucose error grids provide error limits for glucose meters. These criteria help to assess the meter's suitability to prevent acute injury. We present a rationale for an error grid that provides a different set of error limits to help prevent chronic injury in diabetes. For example, glucose values in the no treatment zone of a traditional error grid could be harmful in diabetic retinopathy. The same method comparison data informs both the acute and chronic injury error grids. All of the data are used in an acute injury error grid, whereas only long-term biases populate a chronic injury error grid. These biases can be due to reagent lots and patient specific interferences. An example of a chronic injury glucose error grid is provided using simulated data.
authors.affiliation: Krouwer Consulting, Sherborn, MA, USA jan.krouwer@comcast.net.
authors.forename: Jan S
authors.initials: JS
authors.lastname: Krouwer
authors.affiliation: Alberta Health Services, Walter C. MacKenzie Center, Health Sciences Center, Edmonton, Canada.
authors.forename: George S
authors.initials: GS
authors.lastname: Cembrowski
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D015190:Blood Glucose Self-Monitoring / Q000295:instrumentation / Q000592:standards; D002908:Chronic Disease; D048909:Diabetes Complications / Q000097:blood / Q000175:diagnosis / Q000517:prevention & control*; D003920:Diabetes Mellitus / Q000097:blood* / Q000175:diagnosis; D003951:Diagnostic Errors / Q000706:statistics & numerical data*; D004868:Equipment Failure / Q000706:statistics & numerical data; D006801:Humans; D011358:Product Surveillance, Postmarketing; D012016:Reference Values; D012107:Research Design
chemical_list: D001786:Blood Glucose
keywords: diabetes complications; error grid; long-term bias; surveillance