title: Solid state NMR of lipid model membranes.
abstract: In this chapter we describe the use of solid state nuclear magnetic spectroscopy to study the structure of lyotropic phases and lipid model membranes and show its ability to probe, site specifically, at a sub-Ångstrom resolution. Here, we demonstrate the immense versatility of the technique and its ability to provide information on the different liquid crystalline phases present. A multinuclear for example (31)P, (1)H, and (13)C approach is able to elucidate both the structure and dynamics over a wide variety of timescales. This coupled with a non-perturbing label (2)H is able to provide information such as the order parameters for a wide variety of different liquid phases.
authors.affiliation: Department of Chemistry, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK, arwen.tyler02@imperial.ac.uk.
authors.forename: Arwen I I
authors.initials: AI
authors.lastname: Tyler
authors.forename: James A
authors.initials: JA
authors.lastname: Clarke
authors.forename: John M
authors.initials: JM
authors.lastname: Seddon
authors.forename: Robert V
authors.initials: RV
authors.lastname: Law
mesh_terms: D002247:Carbon Isotopes; D002462:Cell Membrane / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation / Q000379:methods*; D008563:Membrane Lipids / Q000032:analysis / Q000737:chemistry*; D010759:Phosphorus Isotopes
chemical_list: D002247:Carbon Isotopes; D008563:Membrane Lipids; D010759:Phosphorus Isotopes