title: Synapses as therapeutic targets for autism spectrum disorders: an international symposium held in pavia on july 4th, 2014.
abstract: New progresses into the molecular and cellular mechanisms of autism spectrum disorders (ASDs) have been discussed in 1 day international symposium held in Pavia (Italy) on July 4th, 2014 entitled "synapses as therapeutic targets for autism spectrum disorders" (satellite of the FENS Forum for Neuroscience, Milan, 2014). In particular, world experts in the field have highlighted how animal models of ASDs have greatly advanced our understanding of the molecular pathways involved in synaptic dysfunction leading sometimes to "synaptic clinical trials" in children.
authors.affiliation: Pediatric Neurology Unit, Department of Neurosciences, Tor Vergata University , Rome , Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Curatolo
authors.affiliation: Institut National de la Santé et de la Recherche Médicale, Mediterranean Institute of Neurobiology (INMED) , Marseille , France.
authors.forename: Yehezkel
authors.initials: Y
authors.lastname: Ben-Ari
authors.affiliation: CNR Neuroscience Institute and Laboratory of Molecular Neuropathology, Centre for Integrative Biology (CIBIO), University of Trento , Trento , Italy.
authors.forename: Yuri
authors.initials: Y
authors.lastname: Bozzi
authors.affiliation: CNR, Institute of Neurological Sciences (ISN) , Catania , Italy ; Laboratory of Neurobiology, Istituto di Ricovero e Cura a Carattere Scientifico Oasi Maria SS , Troina , Italy.
authors.forename: Maria Vincenza
authors.initials: MV
authors.lastname: Catania
authors.affiliation: Department of Brain and Behavioral Sciences, University of Pavia , Pavia , Italy ; Brain Connectivity Center, Neurological Institute Istituto di Ricovero e Cura a Carattere Scientifico Mondino , Pavia , Italy.
authors.forename: Egidio
authors.initials: E
authors.lastname: D'Angelo
authors.affiliation: Department of Brain and Behavioral Sciences, University of Pavia , Pavia , Italy.
authors.forename: Lisa
authors.initials: L
authors.lastname: Mapelli
authors.affiliation: Department of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University , Providence, RI , USA.
authors.forename: Lindsay M
authors.initials: LM
authors.lastname: Oberman
authors.affiliation: Neuroscience Research Center and NeuroCure Cluster of Excellence, Charité-Universitätsmedizin Berlin , Berlin , Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Rosenmund
authors.affiliation: International School for Advanced Studies (SISSA) , Trieste , Italy ; European Brain Research Institute (EBRI) , Rome , Italy.
authors.forename: Enrico
authors.initials: E
authors.lastname: Cherubini
keywords: ASDs; GABAergic signaling; animal models; synapse; therapeutic target