title: Recent advances in asymmetric synthesis of Р-stereogenic phosphorus compounds.
abstract: This chapter points out significant advances in the asymmetric synthesis of P-chiral organophosphorus compounds with many applications in stereoselective synthesis and in asymmetric catalysis, making reference to updated literature findings as well as the author's original research. Asymmetric addition and cycloaddition reactions, oxidation, including metal catalyzed and non-metal biocatalytic methods are described, in addition to synthetic approaches via nucleophilic substitution of appropriately substituted precursors. Use of chiral organophosphorus compounds in some asymmetric transformations such as hydrogenation and alkyl/arylation reactions is also discussed.
authors.affiliation: Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, Murmanska Str, 1, Kiev, Ukraine, olegkol321@rambler.ru.
authors.forename: Oleg I
authors.initials: OI
authors.lastname: Kolodiazhnyi
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D061565:Cycloaddition Reaction; D004809:Ephedrine / Q000737:chemistry; D006865:Hydrogenation; D015394:Molecular Structure; D009943:Organophosphorus Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010084:Oxidation-Reduction; D013034:Sparteine / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000438:Alcohols; D000588:Amines; D009943:Organophosphorus Compounds; D013034:Sparteine; D004809:Ephedrine