title: Sleep deprived and sweating it out: the effects of total sleep deprivation on skin conductance reactivity to psychosocial stress.
abstract: OBJECTIVE
  We examined how sleep deprivation alters physiological responses to psychosocial stress by evaluating changes in skin conductance.
  
  
  METHODS
  Between-subjects design with one group allocated to 24 h of total sleep deprivation and the other to rested wakefulness.
  
  
  METHODS
  The study took place in a research laboratory.
  
  
  METHODS
  Participants were 40 healthy young adults recruited from a university.
  
  
  METHODS
  Sleep deprivation and feedback.
  
  
  RESULTS
  Electrodermal activity was monitored while participants completed a difficult perceptual task with false feedback. All participants showed increased skin conductance levels following stress. However, compared to well-rested participants, sleep deprived participants showed higher skin conductance reactivity with increasing stress levels.
  
  
  CONCLUSIONS
  Our results suggest that sleep deprivation augments allostatic responses to increasing psychosocial stress. Consequentially, we propose sleep loss as a risk factor that can influence the pathogenic effects of stress.
authors.affiliation: Center for Cognitive Neuroscience, Duke-NUS Graduate Medical School, Singapore.
authors.forename: Jean C J
authors.initials: JC
authors.lastname: Liu
authors.affiliation: Center for Cognitive Neuroscience, Duke-NUS Graduate Medical School, Singapore: Utrecht University, Utrecht, The Netherlands.
authors.forename: Silvan
authors.initials: S
authors.lastname: Verhulst
authors.affiliation: Center for Cognitive Neuroscience, Duke-NUS Graduate Medical School, Singapore.
authors.forename: Stijn A A
authors.initials: SA
authors.lastname: Massar
authors.affiliation: Center for Cognitive Neuroscience, Duke-NUS Graduate Medical School, Singapore.
authors.forename: Michael W L
authors.initials: MW
authors.lastname: Chee
mesh_terms: D000293:Adolescent; D000328:Adult; D005246:Feedback; D005260:Female; D005712:Galvanic Skin Response / Q000502:physiology*; D006801:Humans; D008297:Male; D012146:Rest / Q000502:physiology / Q000523:psychology; D012307:Risk Factors; D012890:Sleep / Q000502:physiology; D012892:Sleep Deprivation / Q000503:physiopathology* / Q000523:psychology*; D013315:Stress, Psychological / Q000503:physiopathology* / Q000523:psychology; D013546:Sweating / Q000502:physiology*; D014851:Wakefulness / Q000502:physiology; D055815:Young Adult
keywords: affect; allostasis; skin conductance; sleep loss; stress; sympathetic nervous system