title: [The diagnostic value of antibodies to annexin and B2-glycoprotein for verification of active course of herpesviral infections of pregnant women].
abstract: The article deals with results of analysis of hemostasiological and immunological alterations under reactivation of herpesviral infections during pregnancy. The formation of pathological thrombinemia, activation of intra-vascular blood clotting, increasing of factors resulted in damage of endothelium under active course of herpesviral infection and increasing risk of development of obstetric pathology are demonstrated. The antibodies to B2-glycoprotein class IgM and antibodies to annexin class IgM, IgG can be operated as diagnostic signs of activation of herpesviral infection during pregnancy.
authors.forename: T I
authors.initials: TI
authors.lastname: Dolgikh
authors.forename: S V
authors.initials: SV
authors.lastname: Barinov
authors.forename: T V
authors.initials: TV
authors.lastname: Kadtsyna
mesh_terms: D000293:Adolescent; D000328:Adult; D017302:Annexins / Q000276:immunology*; D000906:Antibodies / Q000276:immunology; D016022:Case-Control Studies; D005260:Female; D006566:Herpesviridae Infections / Q000175:diagnosis*; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D012698:Serologic Tests; D053482:beta 2-Glycoprotein I / Q000276:immunology*
chemical_list: D017302:Annexins; D000906:Antibodies; D007075:Immunoglobulin M; D053482:beta 2-Glycoprotein I