title: [The development from drug to designer drug].
abstract: Synthetic "designer drugs" with hallucinogenic properties have become increasingly popular among recreational drug users in recent years. Some of the designer drugs are chemically modified drugs previously used in treatment of depression and chronic fatigue. The drugs are available from a large number of internet distributers. There is very little knowledge of the clinical symptoms and how intoxicated people should be treated. We present a review of published literature (including 284 intoxicated patients) and experiences from the Danish poison centre concerning two chemical derivatives of earlier registered drugs.
authors.affiliation: Klinisk Farmakologisk Afdeling, Bispebjerg -Hospital, Bispebjerg Bakke 23, 2400 København NV. bjarke.askaa.03@regionh.dk.
authors.forename: Bjarke
authors.initials: B
authors.lastname: Askaa
authors.forename: Henrik
authors.initials: H
authors.lastname: Horwitz
authors.forename: Vidar André
authors.initials: VA
authors.lastname: Wøien
authors.forename: Lotte C G
authors.initials: LC
authors.lastname: Høgberg
authors.forename: Gesche
authors.initials: G
authors.lastname: Jürgens
mesh_terms: D000470:Alkaloids / Q000008:administration & dosage / Q000494:pharmacology* / Q000506:poisoning; D052117:Benzodioxoles / Q000008:administration & dosage / Q000494:pharmacology* / Q000506:poisoning; D000697:Central Nervous System Stimulants / Q000008:administration & dosage / Q000494:pharmacology* / Q000506:poisoning; D002908:Chronic Disease; D003863:Depression / Q000188:drug therapy; D015198:Designer Drugs / Q000008:administration & dosage / Q000494:pharmacology* / Q000506:poisoning; D005221:Fatigue / Q000188:drug therapy; D006213:Hallucinogens / Q000008:administration & dosage / Q000494:pharmacology / Q000506:poisoning; D006801:Humans; D008996:Monoamine Oxidase Inhibitors / Q000008:administration & dosage / Q000494:pharmacology / Q000506:poisoning; D011039:Poison Control Centers; D011759:Pyrrolidines / Q000008:administration & dosage / Q000494:pharmacology* / Q000506:poisoning; D014363:Tryptamines / Q000008:administration & dosage / Q000494:pharmacology* / Q000506:poisoning; D000094982:Synthetic Cathinone
chemical_list: D000470:Alkaloids; D052117:Benzodioxoles; D000697:Central Nervous System Stimulants; D015198:Designer Drugs; D006213:Hallucinogens; D008996:Monoamine Oxidase Inhibitors; D011759:Pyrrolidines; D014363:Tryptamines; C023665:cathinone; D000094982:Synthetic Cathinone