title: Flow-injection chemiluminescence determination  of acetylsalicylic acid based on its enhancing  effect on the lucigenin–hydrogen  peroxide system.
abstract: A sensitive flow-injection chemiluminescence method for the determination of acetylsalicylic acid is described. It is based on the enhanced chemiluminescent emission of the alkaline lucigenin–H2O2 system by acetylsalicylic acid. The difference in chemiluminescent intensity of alkaline lucigenin–H2O2 in the presence of acetylsalicylic acid from that in the absence of acetylsalicylic acid was linear at acetylsalicylic acid concentrations in the range of 0.0029–47.37 μg/mL, with detection and quantification limits of 0.0011 and 0.0029 μg/mL, respectively. The correlation coefficient of the working curve was 0.9983. The relative standard deviation (n = 10) for 25 μg/mL acetylsalicylic acid is 1.95%. All experimental parameters were optimized. The method was successfully applied to the determination of acetylsalicylic acid in pharmaceutical preparations. The recovery results obtained by the method were satisfactory.
authors.forename: S M
authors.initials: SM
authors.lastname: Wabaidur
authors.forename: S M
authors.initials: SM
authors.lastname: Alam
authors.forename: Z A
authors.initials: ZA
authors.lastname: Alothmana
authors.forename: Gaber
authors.initials: G
authors.lastname: Eldesokya
mesh_terms: D000166:Acridines / Q000737:chemistry*; D001241:Aspirin / Q000032:analysis*; D017022:Flow Injection Analysis / Q000295:instrumentation; D006861:Hydrogen Peroxide / Q000737:chemistry*; D007700:Kinetics; D049449:Luminescence; D015394:Molecular Structure
chemical_list: D000166:Acridines; C033472:10,10'-dimethyl-9,9'-biacridinium; D006861:Hydrogen Peroxide; D001241:Aspirin