title: [Systemic lupus erythematosus and immune-inflammatory thrombophilia].
abstract: Systemic lupus erythematosus (SLE) is an autoimmune disease with causes including activation of innate and adaptive immune systems. SLE patients are with a high risk of thrombosis, which may be due to disease activation, immune complexes, toxic antibodies and high level of inflammation. This article discusses neutrophil/NET factor, antibody factor, platelet factor and particle factor which is involved in coagulation pathways and thrombus formation mechanism under the state of immune disorders in SLE.
authors.affiliation: Clinical Medical College of Yangzhou University, Yangzhou Institute of Hematology, Yangzhou 225001, Jiangsu Province, China.
authors.forename: Zou
authors.initials: Z
authors.lastname: Li
authors.affiliation: Clinical Medical College of Yangzhou University, Yangzhou Institute of Hematology, Yangzhou 225001, Jiangsu Province, China. E-mail: maolujiu918@163.com.
authors.forename: Jian
authors.initials: J
authors.lastname: Gu
mesh_terms: D001777:Blood Coagulation; D001779:Blood Coagulation Factors; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D019851:Thrombophilia / Q000276:immunology*; D013927:Thrombosis
chemical_list: D001779:Blood Coagulation Factors