title: Relationship between carotid intima thickness and silent cerebral infarction in patients with type 2 diabetic nephropathy.
abstract: OBJECTIVE
  To examine the relationship between carotid intima media thickness (CIMT) and silent cerebral infarction (SCI) in order to determine whether CIMT is a predictor of SCI in patients of type 2 diabetic nephropathy.
  
  
  METHODS
  A total of 80 patients of type 2 diabetic nephropathy were selected on the basis of fasting and 2-hour post-prandial blood sugar, 24 hrs albumin estimation in urine, urea and creatinine in the serum. The selected candidates underwent MRI brain and carotid B mode ultrasonography to find out the event of SCI and to evaluate the CIMT respectively.
  
  
  RESULTS
  The SCI was found in 30 (37.5%) patients with type 2 diabetic nephropathy. The mean age, BMI, blood pressure (BP), macroalbuminuria, S. lipids, low GFR, duration of diabetes and CIMT were significantly higher in the subject with SCI than in those without it. Multiple logistic analyses indicated that age, BP, and CIMT were found to be significant and independent risk factors of SCI in type 2 diabetic nephropathy subjects.
  
  
  CONCLUSIONS
  CIMT is a surrogate and reliable predictor of higher risk of SCI among type 2 diabetic nephropathy patients.
authors.forename: D
authors.initials: D
authors.lastname: Kumar
authors.forename: S
authors.initials: S
authors.lastname: Agarwal
authors.forename: R
authors.initials: R
authors.lastname: Karoli
authors.forename: M
authors.initials: M
authors.lastname: Siddiqui
authors.forename: V
authors.initials: V
authors.lastname: Shukla
authors.forename: S
authors.initials: S
authors.lastname: Khanduri
mesh_terms: D000328:Adult; D000368:Aged; D059168:Carotid Intima-Media Thickness; D002544:Cerebral Infarction / Q000175:diagnosis* / Q000209:etiology*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D003928:Diabetic Nephropathies / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors