title: Biomedical applications of holographic microspectroscopy [invited].
abstract: The identification and quantification of specific molecules are crucial for studying the pathophysiology of cells, tissues, and organs as well as diagnosis and treatment of diseases. Recent advances in holographic microspectroscopy, based on quantitative phase imaging or optical coherence tomography techniques, show promise for label-free noninvasive optical detection and quantification of specific molecules in living cells and tissues (e.g., hemoglobin protein). To provide important insight into the potential employment of holographic spectroscopy techniques in biological research and for related practical applications, we review the principles of holographic microspectroscopy techniques and highlight recent studies.
authors.forename: JaeHwang
authors.initials: J
authors.lastname: Jung
authors.forename: Kyoohyun
authors.initials: K
authors.lastname: Kim
authors.forename: HyeonSeung
authors.initials: H
authors.lastname: Yu
authors.forename: KyeoReh
authors.initials: K
authors.lastname: Lee
authors.forename: SeoEun
authors.initials: S
authors.lastname: Lee
authors.forename: SeungHoon
authors.initials: S
authors.lastname: Nahm
authors.forename: HyunJoo
authors.initials: H
authors.lastname: Park
authors.forename: YongKeun
authors.initials: Y
authors.lastname: Park
mesh_terms: D001704:Biopolymers / Q000032:analysis*; D006696:Holography / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008858:Microscopy, Phase-Contrast / Q000379:methods*; D057054:Molecular Imaging / Q000379:methods*; D013057:Spectrum Analysis / Q000379:methods*; D013673:Technology Assessment, Biomedical; D041623:Tomography, Optical Coherence / Q000379:methods*
chemical_list: D001704:Biopolymers