title: Gastrectomy for the treatment of refractory gastric ulceration after radioembolization with 90Y microspheres.
abstract: Transcatheter arterial radioembolization (TARE) with Yttrium-90 ((90)Y)-labeled microspheres has an emerging role in treatment of patients with unresectable hepatocellular carcinoma. Although complication of TARE can be minimized by aggressive pre-evaluation angiography and preventive coiling of aberrant vessels, radioembolization-induced gastroduodenal ulcer can be irreversible and can be life-threatening. Treatment of radioembolization-induced gastric ulcer is challenging because there is a few reported cases and no consensus for management. We report a case of severe gastric ulceration with bleeding that eventually required surgery due to aberrant deposition of microspheres after TARE.
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
authors.forename: Sun Young
authors.initials: SY
authors.lastname: Yim
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. ; Department of Internal Medicine, Cheju Halla General Hospital, Jeju, Korea.
authors.forename: Jin Dong
authors.initials: JD
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
authors.forename: Jin Yong
authors.initials: JY
authors.lastname: Jung
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
authors.forename: Chang Ha
authors.initials: CH
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
authors.forename: Yeon Seok
authors.initials: YS
authors.lastname: Seo
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
authors.forename: Hyung Joon
authors.initials: HJ
authors.lastname: Yim
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
authors.forename: Soon Ho
authors.initials: SH
authors.lastname: Um
authors.affiliation: Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
authors.forename: Ho Sang
authors.initials: HS
authors.lastname: Ryu
authors.affiliation: Department of Radiology, Korea University College of Medicine, Seoul, Korea.
authors.forename: Yun Hwan
authors.initials: YH
authors.lastname: Kim
authors.affiliation: Department of Surgery, Korea University College of Medicine, Seoul, Korea.
authors.forename: Chong Suk
authors.initials: CS
authors.lastname: Kim
authors.affiliation: Department of Pathology, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Eun
authors.initials: E
authors.lastname: Shin
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis* / Q000532:radiotherapy; D004621:Embolization, Therapeutic / Q000009:adverse effects*; D005743:Gastrectomy; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D005773:Gastroscopy; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000532:radiotherapy; D008279:Magnetic Resonance Imaging; D008297:Male; D008863:Microspheres; D019275:Radiopharmaceuticals / Q000627:therapeutic use; D013270:Stomach / Q000473:pathology; D013276:Stomach Ulcer / Q000209:etiology* / Q000601:surgery; D015021:Yttrium Radioisotopes / Q000737:chemistry
chemical_list: D019275:Radiopharmaceuticals; D015021:Yttrium Radioisotopes
keywords: Gastrectomy; Gastric ulcer; Hepatocellular carcinoma; Radioembolization; Yttrium-90