title: Complete genome sequence of cell culture-attenuated Guinea pig cytomegalovirus cloned as an infectious bacterial artificial chromosome.
abstract: The complete genome sequence of attenuated guinea pig cytomegalovirus cloned as bacterial artificial chromosome N13R10 was determined. Comparison to pathogenic salivary gland-derived virus revealed 13 differences, 1 of which disrupted overlapping open reading frames encoding GP129 and GP130. Attenuation of N13R10 may arise from an inability to express GP129 and/or GP130.
authors.affiliation: University of North Carolina School of Medicine, Lineberger Comprehensive Cancer Center and Department of Microbiology and Immunology, Chapel Hill, North Carolina, USA.
authors.forename: Dongmei
authors.initials: D
authors.lastname: Yang
authors.affiliation: Virginia Commonwealth University School of Medicine, Department of Pediatrics, Richmond, Virginia, USA.
authors.forename: Zohaib
authors.initials: Z
authors.lastname: Alam
authors.affiliation: Virginia Commonwealth University School of Medicine, Department of Pediatrics, Richmond, Virginia, USA.
authors.forename: Xiaohong
authors.initials: X
authors.lastname: Cui
authors.affiliation: University of North Carolina School of Medicine, Lineberger Comprehensive Cancer Center and Department of Microbiology and Immunology, Chapel Hill, North Carolina, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Chen
authors.affiliation: University of North Carolina School of Medicine, Lineberger Comprehensive Cancer Center and Department of Microbiology and Immunology, Chapel Hill, North Carolina, USA.
authors.forename: Carly J
authors.initials: CJ
authors.lastname: Sherrod
authors.affiliation: Virginia Commonwealth University School of Medicine, Department of Pediatrics, Richmond, Virginia, USA mmcvoy@vcu.edu.
authors.forename: Michael A
authors.initials: MA
authors.lastname: McVoy
authors.affiliation: University of Minnesota Medical School, Department of Pediatrics, Division of Pediatric Infectious Diseases and Immunology, Minneapolis, Minnesota, USA.
authors.forename: Mark R
authors.initials: MR
authors.lastname: Schleiss
authors.affiliation: University of North Carolina School of Medicine, Lineberger Comprehensive Cancer Center and Department of Microbiology and Immunology, Chapel Hill, North Carolina, USA.
authors.forename: Dirk P
authors.initials: DP
authors.lastname: Dittmer