title: Tripe palm: a cutaneous manifestation of gastric carcinoma.
abstract: Case 1: A 43-year-old farmer attended our clinic with increasing fatigability, nausea, loss of appetite, loss of weight, postprandial fullness along with thyroid-stimulating hormone value of 0.4 mIU/L and anaemia without any history of cough, chest pain, haemoptysis, osmotic symptoms, haematemesis or malena. The patient received albendazole and iron preparations before attending our clinic. Case 2: A 51-year-old woman, a known patient with type 2 diabetes for the past 8 years, on gliclazide and metformin (2 g), with unaltered liver function test and renal function test, presented with symptoms similar to case 1 of upper gastrointestinal features along with a history of weight loss (about 6 kg) over the past 3 months. Metformin was withdrawn by her primary care physician but her symptoms persisted. A velvety appearance with pigmentation on the palms of the hands was found in both cases. Endoscopy revealed an irregular mass in the stomach. Subsequently, both patients were diagnosed to have gastric adenocarcinoma.
authors.affiliation: Department of Endocrinology, IPGME & R, Kolkata, West Bengal, India.
authors.forename: Partha Pratim
authors.initials: PP
authors.lastname: Chakraborty
authors.affiliation: Department of Endocrinology, IPGME & R, Kolkata, West Bengal, India.
authors.forename: Saumik
authors.initials: S
authors.lastname: Datta
authors.affiliation: Department of Internal Medicine, Medical College, Kolkata, West Bengal, India.
authors.forename: Sanjay Kumar
authors.initials: SK
authors.lastname: Mandal
authors.affiliation: Department of Endocrinology, IPGME & R, Kolkata, West Bengal, India.
authors.forename: Manoj
authors.initials: M
authors.lastname: Kumar
mesh_terms: D000052:Acanthosis Nigricans / Q000209:etiology* / Q000473:pathology; D000230:Adenocarcinoma / Q000150:complications / Q000175:diagnosis*; D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D005221:Fatigue / Q000209:etiology; D001068:Feeding and Eating Disorders / Q000209:etiology; D005260:Female; D006225:Hand / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000150:complications / Q000175:diagnosis*; D015431:Weight Loss