title: Application of ion chromatography in clinical studies and pharmaceutical industry.
abstract: Ion chromatography is a well-established regulatory method for analyzing anions and cations in environmental, food and many other samples. It offers an enormous range of possibilities for selecting stationary and mobile phases. Additionally, it usually helps to solve various separation problems, particularly when it is combined with different detection techniques. Ion chromatography can also be used to determine many ions and substances in clinical and pharmaceutical samples. It provides: availability of high capacity stationary phases and sensitive detectors; simple sample preparation; avoidance of hazardous chemicals; decreased sample volumes; flexible reaction options on a changing sample matrix to be analyzed; or the option to operate a fully-automated system. This paper provides a short review of the ion chromatography applications for determining different inorganic and organic substances in clinical and pharmaceutical samples.
authors.affiliation: Institute of Environmental Engineering of Polish Academy of Sciences, Sklodowska-Curie 34 Street, 41-819 Zabrze, Poland. rajmund.michalski@ipis.zabrze.pl.
authors.forename: Rajmund
authors.initials: R
authors.lastname: Michalski
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation / Q000379:methods; D002852:Chromatography, Ion Exchange / Q000295:instrumentation / Q000379:methods*; D004345:Drug Industry / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D007477:Ions / Q000737:chemistry
chemical_list: D007477:Ions