title: Prevalence of Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium in asymptomatic patients under 30 years of age screened in a French sexually transmitted infections clinic.
abstract: BACKGROUND
  An increasing prevalence of sexually transmitted infections (STI) has been noted in France over the past decade. Asymptomatic carriage may be high in patients infected with Chlamydia trachomatis attending free and anonymous screening centres (CDAG) and information, diagnosis and screening centres for STI (CIDDIST). In these centres, systematic C. trachomatis detection is recommended in women ≤25 years and in men ≤30 years.
  
  
  OBJECTIVE
  This study aimed at estimating the prevalence of C. trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium in asymptomatic patients younger than 30 years attending a CDAG-CIDDIST.
  
  
  METHODS
  A free systematic screening for C. trachomatis, N. gonorrhoeae and M. genitalium was offered to asymptomatic subjects under 30 years attending the Montpellier CDAG-CIDDIST from April to August 2009. Pathogens were identified by PCR in first void urine samples.
  
  
  RESULTS
  Of the 1381 subjects included (53.8% women and 46.2% men), 105 (42.9% men and 57.1% women) tested positive for C. trachomatis (7.6%, 95% CI [6.3;9.13]); eight (seven men and one woman) tested positive for M. genitalium (0.58% [0.2;1]) of whom two were infected with C. trachomatis ; five (two men and three women) tested positive for N. gonorrhoeae (0.36% [0.1;0.8]) of whom three were infected with C. trachomatis.
  
  
  CONCLUSIONS
  This study confirmed the need for C. trachomatis screening in all patients under 30 years. Our results did not support a systematic screening for N. gonorrhoeae and M. genitalium in urine samples in this kind of facility.
authors.affiliation: Unité de Recherche Clinique et Epidémiologie, Hôpital La Colombière, Montpellier, France.
authors.forename: Béatrice
authors.initials: B
authors.lastname: Clarivet
authors.affiliation: CDAG/CIDDIST.
authors.forename: Eric
authors.initials: E
authors.lastname: Picot
authors.affiliation: Département de Bactériologie, Hôpital Arnaud de Villeneuve, Montpellier, France, Université Montpellier 1 UMR 5119 ECOSYM, Montpellier, France.
authors.forename: Hélène
authors.initials: H
authors.lastname: Marchandin
authors.affiliation: CDAG/CIDDIST.
authors.forename: Vincent
authors.initials: V
authors.lastname: Tribout
authors.affiliation: CDAG/CIDDIST.
authors.forename: Nadia
authors.initials: N
authors.lastname: Rachedi
authors.affiliation: DRASS Languedoc-Roussillon.
authors.forename: Eric
authors.initials: E
authors.lastname: Schwartzentruber
authors.affiliation: Observatoire Régional de la Santé du Languedoc Roussillon.
authors.forename: Bernard
authors.initials: B
authors.lastname: Ledésert
authors.affiliation: Service de Dermatologie Hôpital Saint-Eloi 34295 Montpellier, France, Inserm Unité1058, UFR de Pharmacie 15, Montpellier, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Dereure
authors.affiliation: Service de Dermatologie Hôpital Saint-Eloi 34295 Montpellier, France, Inserm Unité1058, UFR de Pharmacie 15, Montpellier, France.
authors.forename: Bernard
authors.initials: B
authors.lastname: Guillot
authors.affiliation: Unité de Recherche Clinique et Epidémiologie, Hôpital La Colombière, Montpellier, France, Centre d'Investigation Clinique, Inserm Unité 1001.
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Picot
mesh_terms: D000328:Adult; D000367:Age Factors; D000554:Ambulatory Care Facilities; D058345:Asymptomatic Infections / Q000453:epidemiology; D002353:Carrier State / Q000175:diagnosis / Q000453:epidemiology; D002690:Chlamydia Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology; D002692:Chlamydia trachomatis; D060085:Coinfection / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D005602:France / Q000453:epidemiology; D006069:Gonorrhea / Q000175:diagnosis / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008403:Mass Screening; D009175:Mycoplasma Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology; D045704:Mycoplasma genitalium; D015995:Prevalence; D014556:Urine / Q000382:microbiology; D055815:Young Adult
keywords: Chlamydia trachomatis; Mycoplasma genitalium; Neisseria gonorrhoeae; asymptomatic; prevalence; sexually transmitted infections