title: Synthesis of brassinosteroids analogues from laxogenin and their plant growth promotion.
abstract: Four steroid saponins (2-5) and three derivatives (6-8) were synthesised from laxogenin. Four of them were new compounds: (25R)-3β-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyloxy)-5α-spirostan-6-one (3), (25R)-3β-(β-D-galactopyranosyloxy)-5α-spirostan-6-one (5), 3β,16-diacetyl-26-hydroxy-5α-cholestan-6,22-dione (6) and 16-acetyl-3β,26-dihydroxy-5α-cholestan-6,22-dione (7). All the compounds showed plant growth-promoting activity in the radish hypocotyl elongation and cotyledon expansion bioassay. Above all, 2 and 6 were found to be more active.
authors.affiliation: a College of Life Science, Northwest A&F University , No. 22 Xinong Road, Yangling, Shaanxi 712100 , P.R. China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Wang
authors.forename: Jing
authors.initials: J
authors.lastname: Xu
authors.forename: XiaoLi
authors.initials: X
authors.lastname: Liu
authors.forename: WenXiu
authors.initials: W
authors.lastname: Gong
authors.forename: CunLi
authors.initials: C
authors.lastname: Zhang
mesh_terms: D060406:Brassinosteroids / Q000138:chemical synthesis*; D015394:Molecular Structure; D010937:Plant Growth Regulators / Q000138:chemical synthesis*; D031224:Raphanus / Q000187:drug effects / Q000254:growth & development; D012503:Saponins / Q000138:chemical synthesis*; D013150:Spirostans / Q000737:chemistry*
chemical_list: D060406:Brassinosteroids; D010937:Plant Growth Regulators; D012503:Saponins; D013150:Spirostans; C410957:laxogenin
keywords: brassinosteroids analogues; laxogenin; plant growth-promoting activity