title: Primary cutaneous angiosarcoma on the nose in a patient with multiple nonmelanoma skin cancers.
abstract: Cutaneous angiosarcoma is an uncommon, potentially metastatic and highly aggressive vascular tumor that may arise as de novo or be associated with previous radiotherapy. A 70-year-old female with a solitary lesion on the nose was initially diagnosed as actinic keratosis. However, when the recurring lesion at the same region within 6 months was reexcised, the histological diagnosis was definitively established as well-differentiated angiosarcoma. This case was presented in order to increase awareness of this rare malignancy in an uncommon localisation, especially in the light of pathological findings. Moreover, occurrence of cutaneous angiosarcoma within a short period following a previous excision in a patient with a history of multiple nonmelanoma skin cancers was interestingly pointed out.
authors.affiliation: Department of Pathology, Dr. Lutfi Kirdar Kartal Educational and Research Hospital, Turkey.
authors.forename: Kayhan
authors.initials: K
authors.lastname: Basak
authors.affiliation: Department of Dermatology, Suleyman Demirel University, Faculty of Medicine, Turkey.
authors.forename: Pinar Yuksel
authors.initials: PY
authors.lastname: Basak
authors.affiliation: Department of Plastic and Reconstructif Surgery, Dr. Lutfi Kirdar Kartal Educational and Research Hospital, Turkey.
authors.forename: Hakan
authors.initials: H
authors.lastname: Demirel
authors.affiliation: Department of Pathology, Dr. Lutfi Kirdar Kartal Educational and Research Hospital, Turkey.
authors.forename: Nimet
authors.initials: N
authors.lastname: Karadayi
mesh_terms: D000368:Aged; D005260:Female; D006394:Hemangiosarcoma / Q000378:metabolism / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007150:Immunohistochemistry; D009378:Neoplasms, Multiple Primary; D009669:Nose Neoplasms / Q000378:metabolism / Q000473:pathology / Q000601:surgery*; D012878:Skin Neoplasms / Q000378:metabolism / Q000473:pathology / Q000601:surgery*