title: Congenital left ventricular aneurysm coexisting with left ventricular non-compaction in a newborn.
abstract: Described herein is the case of a rare combination of congenital left ventricular (LV) aneurysm and left ventricular non-compaction (LVNC) in a newborn. The patient developed refractory heart failure soon after birth and died at 5 months of age. The etiology of both congenital LV aneurysm and LVNC seems to be maldevelopment of the ventricular myocardium during early fetal life. Treatment should be individually tailored depending on clinical severity, and treatment options are limited. Given that this combination of congenital LV aneurysm and LVNC is significantly associated with poor prognosis, it appears that patients with congenital LV aneurysm and LVNC are candidates for early, aggressive intervention, including surgical aneurysmectomy and evaluation for transplantation. It is important to be aware of this combination of congenital LV aneurysm and LVNC, and to make earlier decisions on therapeutic strategy.
authors.affiliation: Department of Pediatrics, School of Medicine, Hirosaki University, Hirosaki, Japan.
authors.forename: Katsuki
authors.initials: K
authors.lastname: Ootani
authors.forename: Jun
authors.initials: J
authors.lastname: Shimada
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Kitagawa
authors.forename: Yuki
authors.initials: Y
authors.lastname: Konno
authors.forename: Fumitake
authors.initials: F
authors.lastname: Miura
authors.forename: Toru
authors.initials: T
authors.lastname: Takahashi
authors.forename: Etsuro
authors.initials: E
authors.lastname: Ito
authors.forename: Kouta
authors.initials: K
authors.lastname: Ichinose
authors.forename: Susumu
authors.initials: S
authors.lastname: Yonesaka
mesh_terms: D005260:Female; D006322:Heart Aneurysm / Q000150:complications* / Q000151:congenital*; D006352:Heart Ventricles; D006801:Humans; D007231:Infant, Newborn; D056830:Isolated Noncompaction of the Ventricular Myocardium / Q000150:complications*
keywords: congenital left ventricular aneurysm; etiology; heart failure; left ventricular non-compaction; newborn