title: Quantitative fraction evaluation of dermal collagen and elastic fibres in the skin samples obtained in two orientations from the trunk region.
abstract: Background. Histomorphic evaluation of dermal collagen and elastic fibres was analysed by image analysis technique. The quantification of dermal elements was performed in skin tissues, collected in horizontal and vertical directions from trunk region and discussed under the perspective of consequences of scar related complications. Materials and Method. Total number of 200 skin samples collected from 5 areas of trunk region were processed histologically and subjected to tissue-quant image analysis. Statistical analysis involving mean with SEM and paired t test by SPSS were employed to the percentage values obtained from image analysis. Result. Among the chosen 5 areas of trunk region, abdomen showed the statistically significant difference for both collagen and elastic content between horizontal and vertical orientations (P< 0.05), whereas upper back, presternal, and lateral chest areas showed significant difference (P< 0.05) only for collagen and groin only for elastic content. Conclusion. The differences in the distribution of dermal collagen and elastic fibres in 2 directions of the samples from the same areas might be attributed to final outcome of wound healing process by influencing the appearance and behaviour of scar related complications in the region of trunk.
authors.affiliation: Department of Anatomy, Melaka Manipal Medical College, Manipal University, Manipal Campus, Manipal, India.
authors.forename: Naveen
authors.identifier: 0000-0003-2805-779X
authors.initials: N
authors.lastname: Kumar
authors.affiliation: Consultant Plastic Surgeon, King Abdulaziz Hospital, Al Jouf, Saudi Arabia.
authors.forename: Pramod
authors.initials: P
authors.lastname: Kumar
authors.affiliation: Department of Anatomy, Melaka Manipal Medical College, Manipal University, Manipal Campus, Manipal, India.
authors.forename: Satheesha
authors.initials: S
authors.lastname: Nayak Badagabettu
authors.affiliation: Department of Information Science, Manipal School of Information Science, Manipal University, Manipal, India.
authors.forename: Keerthana
authors.initials: K
authors.lastname: Prasad
authors.affiliation: Department of Pathology, Kasturba Medical College, Manipal University, Manipal, India.
authors.forename: Ranjini
authors.initials: R
authors.lastname: Kudva
authors.affiliation: Department of Pathology, Yenepoya University, Deralakatte, Mangalore, India.
authors.forename: Coimbatore Vasudevarao
authors.initials: CV
authors.lastname: Raghuveer