title: Construction of erythrinane skeleton via Pd(0)-catalyzed intramolecular dearomatization of para-aminophenols.
abstract: A novel Pd(0)-catalyzed intramolecular arylative dearomatization of para-aminophenol derivatives is described. In the presence of 1.25 mol % [Pd(C3H5)Cl]2 and 3.75 mol % RuPhos, the arylative dearomatization reaction proceeds smoothly for a broad range of substrates, offering an efficient synthetic route to erythrinane derivatives in excellent yields.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Lu, Shanghai 200032, China.
authors.forename: Ren-Qi
authors.initials: RQ
authors.lastname: Xu
authors.forename: Qing
authors.initials: Q
authors.lastname: Gu
authors.forename: Wen-Ting
authors.initials: WT
authors.lastname: Wu
authors.forename: Zhuo-An
authors.initials: ZA
authors.lastname: Zhao
authors.forename: Shu-Li
authors.initials: SL
authors.lastname: You
mesh_terms: D000627:Aminophenols / Q000737:chemistry*; D002384:Catalysis; D010165:Palladium / Q000737:chemistry*
chemical_list: D000627:Aminophenols; D010165:Palladium; C026729:4-aminophenol