title: Biodegradable stimuli-responsive polypeptide materials prepared by ring opening polymerization.
abstract: The stimuli-responsive polypeptides have drawn extensive attention because of their promising applications in biotechnology considering their biocompatibility, biodegradability, and bioactivity. In this tutorial review, we summarize the most recent progress in this area, including thermo-, redox-, photo-, and biomolecule responsive polypeptides over the past decade. The design and synthesis of stimuli-responsive polypeptides will be briefly introduced. The correlation between the structure and properties, particularly the effects of polypeptide conformation, will be emphasized here. In addition, the applications of stimuli-responsive polypeptides in controlled drug release and tissue engineering are briefly discussed.
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. fuwenxin@iccas.ac.cn zbli@iccas.ac.cn.
authors.forename: Yong
authors.initials: Y
authors.lastname: Shen
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Fu
authors.forename: Wenxin
authors.initials: W
authors.lastname: Fu
authors.forename: Zhibo
authors.initials: Z
authors.lastname: Li
mesh_terms: D001709:Biotechnology; D008958:Models, Molecular; D010455:Peptides; D011108:Polymers; D013696:Temperature
chemical_list: D010455:Peptides; D011108:Polymers