title: Cardiac inflammatory myofibroblastic tumor: a comprehensive review of the literature.
abstract: Although inflammatory myofibroblastic tumors (IMTs) can be found in virtually every major organ, cardiac origin is rare. After recently providing care to a child who presented with a significant myocardial infarction, interest in this rare tumor was piqued. We describe a comprehensive review of cardiac IMT, including information on nomenclature, epidemiology, clinical features, pathogenesis, gross/histological features, immunohistochemical profile, diagnosis, treatment, and prognosis. Fifty-seven cases were identified in the literature. Interestingly, our case represents the seventh case of coronary artery involvement reported. Moreover, it was found that an initial presentation of sudden death most commonly involves the coronary arteries.
authors.affiliation: Department of Cardiothoracic Surgery, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
authors.forename: Amanda L
authors.initials: AL
authors.lastname: Eilers
authors.affiliation: Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
authors.forename: Alia N
authors.initials: AN
authors.lastname: Nazarullah
authors.affiliation: Department of Surgery, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
authors.forename: Edward S
authors.initials: ES
authors.lastname: Shipper
authors.affiliation: Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
authors.forename: Jaishree S
authors.initials: JS
authors.lastname: Jagirdar
authors.affiliation: Department of Cardiothoracic Surgery, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
authors.forename: John H
authors.initials: JH
authors.lastname: Calhoon
authors.affiliation: Department of Cardiothoracic Surgery, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA husain@uthscsa.edu.
authors.forename: S Adil
authors.initials: SA
authors.lastname: Husain
mesh_terms: D006104:Granuloma, Plasma Cell / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000601:surgery; D006338:Heart Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D011379:Prognosis; D016019:Survival Analysis; D009626:Terminology as Topic
keywords: cardiac; inflammatory myofibroblastic tumor; inflammatory pseudotumor; plasma cell granuloma