title: Effects of glucan on bone marrow.
abstract: Bone marrow damage represents a significant problem in cancer treatment. Therefore, it is clear that the pharmacologic protection against bone marrow damage is of considerable interest, since the development of novel and effective medical approaches to combat radiation or cytotoxic damage are of major importance not only to the medical field but also to several industries and the military. This review represents a summary of our knowledge of the effects of various glucans on bone marrow protection.
authors.affiliation: 1 Institute of Microbiology, Czech Academy of Sciences, Prague, Czech Republic ; 2 University of Louisville, Department of Pathology, Louisville, KY, USA.
authors.forename: Petr
authors.initials: P
authors.lastname: Sima
authors.affiliation: 1 Institute of Microbiology, Czech Academy of Sciences, Prague, Czech Republic ; 2 University of Louisville, Department of Pathology, Louisville, KY, USA.
authors.forename: Luca
authors.initials: L
authors.lastname: Vannucci
authors.affiliation: 1 Institute of Microbiology, Czech Academy of Sciences, Prague, Czech Republic ; 2 University of Louisville, Department of Pathology, Louisville, KY, USA.
authors.forename: Vaclav
authors.initials: V
authors.lastname: Vetvicka
keywords: Glucan; bone marrow; chemotherapy; irradiation; mice