title: The endoplasmic reticulum: a dynamic and well-connected organelle.
abstract: The endoplasmic reticulum forms the first compartment in a series of organelles which comprise the secretory pathway. It takes the form of an extremely dynamic and pleomorphic membrane-bounded network of tubules and cisternae which have numerous different cellular functions. In this review, we discuss the nature of endoplasmic reticulum structure and dynamics, its relationship with closely associated organelles, and its possible function as a highway for the distribution and delivery of a diverse range of structures from metabolic complexes to viral particles.
authors.affiliation: Department of Biological and Medical Sciences, Oxford Brookes University, Oxford, OX3 0BP, UK.
authors.forename: Chris
authors.initials: C
authors.lastname: Hawes
authors.forename: Petra
authors.initials: P
authors.lastname: Kiviniemi
authors.forename: Verena
authors.initials: V
authors.lastname: Kriechbaumer
mesh_terms: D004721:Endoplasmic Reticulum / Q000378:metabolism*; D007425:Intracellular Membranes / Q000378:metabolism; D042541:Intracellular Space / Q000378:metabolism; D009068:Movement; D009218:Myosins / Q000378:metabolism
chemical_list: D009218:Myosins
keywords: Actin; Golgi; endomembranes; microtubules; myosin