title: The synthesis of diarylsulfones with simple arenes and K2S2O8 through double C-S bond formation.
abstract: An unprecedented double C-S bond formation method has been developed to prepare both symmetric and unsymmetric diarylsulfones with simple arenes in a single step. This represents the first example that K2S2O8 can be employed as a highly effective sulfonating agent to synthesize diarylsulfones. The reaction demonstrates excellent reactivity, good functional group tolerance and high yields.
authors.affiliation: MOE Key Laboratory of Protein Sciences, Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China. yrao@mail.tsinghua.edu.cn.
authors.forename: Yiqing
authors.initials: Y
authors.lastname: Yang
authors.forename: Zhang
authors.initials: Z
authors.lastname: Chen
authors.forename: Yu
authors.initials: Y
authors.lastname: Rao
mesh_terms: D000089:Acetic Anhydrides / Q000737:chemistry; D005463:Fluoroacetates / Q000737:chemistry; D008698:Mesylates / Q000737:chemistry; D017680:Potassium Compounds / Q000737:chemistry*; D013431:Sulfates / Q000737:chemistry*; D013450:Sulfones / Q000138:chemical synthesis*
chemical_list: D000089:Acetic Anhydrides; D005463:Fluoroacetates; D008698:Mesylates; D017680:Potassium Compounds; D013431:Sulfates; D013450:Sulfones; C017958:trifluoroacetic anhydride; C009007:potassium persulfate; C012077:trifluoromethanesulfonic acid