title: Stereotactic body radiation therapy for liver metastasis--case report and review of the literature. The role of patient preparation, treatment planning and its delivery.
abstract: BACKGROUND
  Stereotactic body radiation therapy (SBRT) is reported as a well-tolerated treatment modality, which offers a long-term tumor control.
  
  
  OBJECTIVE
  The aim of the following study is to present the place of proposed treatment preparation and its delivery for liver metastases with conventional linear accelerator among reported SBRT protocols.
  
  
  METHODS
  We present our treatment preparation, planning and set-up verification procedure performed for liver metastasis. The prescription dose of 45 Gy was delivered in 3 fractions with cone beam computed tomography and 2-dimensional guidance.
  
  
  RESULTS
  The conventional 3-dimensional conformal plan, which fulfilled all dose constraints for target and organs at risk, was accepted for the treatment. Almost for all performed patient position verifications, on-line evaluated results were kept under 5 mm.
  
  
  CONCLUSIONS
  The analysis presents the possible way of treating patients with liver metastasis. The SBRT treatment prepared and verified according our protocol can be implemented in clinical practice for a vast majority of such patients. The literature validation of our liver SBRT protocol showed that it has the potential for ensuring the effective and patient-friendly delivery.
authors.affiliation: Department of Medical Physics, Greater Poland Cancer Centre, Poznan, Poland.
authors.forename: Marta
authors.initials: M
authors.lastname: Adamczyk
authors.forename: Magdalena
authors.initials: M
authors.lastname: Fundowicz
mesh_terms: D019583:Dose Fractionation, Radiation; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000556:secondary* / Q000601:surgery*; D011829:Radiation Dosage; D016634:Radiosurgery / Q000009:adverse effects; D011880:Radiotherapy Planning, Computer-Assisted; D016896:Treatment Outcome; D047368:Tumor Burden