title: A monomeric photosensitizer for targeted cancer therapy.
abstract: A targeted photosensitizer used in photodynamic therapy (PDT) was fabricated by incorporation of zinc phthalocyanine (ZnPc) and folic acid (FA) into polyvinylpyrrolidone (PVP) micelles, which exhibits excellent anticancer performance revealed by both in vitro studies and in vivo tests.
authors.affiliation: State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, P. R. China. weimin@mail.buct.edu.cn.
authors.forename: Ruizheng
authors.initials: R
authors.lastname: Liang
authors.forename: Lina
authors.initials: L
authors.lastname: Ma
authors.forename: Lele
authors.initials: L
authors.lastname: Zhang
authors.forename: Chunyang
authors.initials: C
authors.lastname: Li
authors.forename: Wendi
authors.initials: W
authors.lastname: Liu
authors.forename: Min
authors.initials: M
authors.lastname: Wei
authors.forename: Dan
authors.initials: D
authors.lastname: Yan
authors.forename: David G
authors.initials: DG
authors.lastname: Evans
authors.forename: Xue
authors.initials: X
authors.lastname: Duan
mesh_terms: D000818:Animals; D004337:Drug Carriers / Q000008:administration & dosage* / Q000737:chemistry; D005492:Folic Acid / Q000008:administration & dosage* / Q000737:chemistry; D056945:Hep G2 Cells; D006801:Humans; D007211:Indoles / Q000008:administration & dosage* / Q000737:chemistry; D054833:Isoindoles; D008297:Male; D008807:Mice, Inbred BALB C; D008823:Micelles; D009369:Neoplasms / Q000188:drug therapy* / Q000378:metabolism; D061848:Optical Imaging; D009942:Organometallic Compounds / Q000008:administration & dosage* / Q000737:chemistry; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000008:administration & dosage* / Q000737:chemistry; D011205:Povidone / Q000737:chemistry; D026082:Singlet Oxygen / Q000737:chemistry; D013472:Sunlight; D017967:Zinc Compounds
chemical_list: D004337:Drug Carriers; D007211:Indoles; D054833:Isoindoles; D008823:Micelles; D009942:Organometallic Compounds; D017319:Photosensitizing Agents; D017967:Zinc Compounds; C052159:Zn(II)-phthalocyanine; D026082:Singlet Oxygen; D005492:Folic Acid; D011205:Povidone