title: [Risk factors for multidrug-resistant Pseudomonas aeruginosa infection, in a tertiary hospital in Colombia].
abstract: BACKGROUND
  multi-resistant Pseudomonas aeruginosa (MR) is frequently associated with healthcare infections. Its epidemiology is complex and few studies help to understand it. A study about risk factors associated with this type of bacteria is needed.
  
  
  OBJECTIVE
  To determine risk factors associated with MR P. aeruginosa infection in hospitalized patients from the Hospital Universitario San Vicente Foundation-Medellin.
  
  
  METHODS
  case-control study to identify risk factors associated with infection by MR P. aeruginosa.
  
  
  RESULTS
  140 patients were included, 70 in each group. Bivariate analysis found association with previous use of carbapenems (OR 3.12 - IC 1.21 to 8.03, p = 0.02), aminoglycosides (OR 5.09 - CI: 1.38 to 18, 77, p = 0.01) and days of stay prior to isolation of the organism (OR 1.03 - CI: 1.01-1.05, p = 0.01). In multivariate analysis MR P. aeruginosa infection was associated with hospital stay (OR 1.03 - IC 1.01 to 1.05), use of aminoglycosides (OR 1.30 to 19.28) and treatment with two or more antimicrobials in the last 30 days (OR 3.09 - CI: 1.26 to 7.58). The risk of developing infection was 3% per day of hospital stay prior to isolation of the agent.
  
  
  CONCLUSIONS
  Developing MR P. aeruginosa infection was associated with prior use of antimicrobials and prior hospital stay.
authors.forename: Ana Claudia
authors.initials: AC
authors.lastname: Ossa-Giraldo
authors.forename: Lina María
authors.initials: LM
authors.lastname: Echeverri-Toro
authors.forename: Zila Margarita
authors.initials: ZM
authors.lastname: Santos
authors.forename: Mónica Giseth
authors.initials: MG
authors.lastname: García
authors.forename: Yuli
authors.initials: Y
authors.lastname: Agudelo
authors.forename: Faiver
authors.initials: F
authors.lastname: Ramírez
authors.forename: Sigifredo
authors.initials: S
authors.lastname: Ospina
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D003105:Colombia; D003428:Cross Infection / Q000382:microbiology*; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011552:Pseudomonas Infections / Q000209:etiology* / Q000382:microbiology; D011550:Pseudomonas aeruginosa; D012307:Risk Factors; D062606:Tertiary Care Centers