title: Association of isolated systolic, isolated diastolic, and systolic-diastolic masked hypertension with carotid artery intima-media thickness.
abstract: Masked hypertension (MH) is associated with advanced target organ damage. However, patients with MH constitute a group of individuals with heterogeneous characteristics concerning their ambulatory blood pressure (BP) status. The aim of this study was to evaluate the association of isolated systolic MH, isolated diastolic MH, and systolic/diastolic MH with carotid artery intima-media thickness (CIMT). A total of 101 patients with MH underwent carotid artery ultrasonographic measurements. The patients were divided into three groups according to office and daytime BP values: isolated systolic MH, isolated diastolic MH, and systolic/diastolic MH. Patients with isolated systolic (n=36) (0.771 mm) and systolic/diastolic MH (n=37) (0.775 mm) had significantly (P<.05) higher CIMT values than those with isolated diastolic MH (n=28) (0.664 mm), even after adjustment for baseline characteristics and risk factors. Patients with isolated systolic and systolic/diastolic MH presented significantly higher CIMT values compared with patients with isolated diastolic MH.
authors.affiliation: Department of Clinical Therapeutics, Medical School of Athens, Alexandra Hospital, Athens, Greece.
authors.forename: Efstathios
authors.initials: E
authors.lastname: Manios
authors.forename: Fotios
authors.initials: F
authors.lastname: Michas
authors.forename: Kimon
authors.initials: K
authors.lastname: Stamatelopoulos
authors.forename: Eleni
authors.initials: E
authors.lastname: Koroboki
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Stellos
authors.forename: Iliana
authors.initials: I
authors.lastname: Tsouma
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Vemmos
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Zakopoulos
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001794:Blood Pressure / Q000502:physiology*; D018660:Blood Pressure Monitoring, Ambulatory; D002339:Carotid Arteries / Q000000981:diagnostic imaging* / Q000473:pathology; D059168:Carotid Intima-Media Thickness; D003430:Cross-Sectional Studies; D003971:Diastole / Q000502:physiology*; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D059468:Masked Hypertension / Q000473:pathology / Q000503:physiopathology*; D008875:Middle Aged; D012307:Risk Factors; D013599:Systole / Q000502:physiology*; D014463:Ultrasonography