title: Tissue-informative mechanism for wearable non-invasive continuous blood pressure monitoring.
abstract: Accurate continuous direct measurement of the blood pressure is currently available thru direct invasive methods via intravascular needles, and is mostly limited to use during surgical procedures or in the intensive care unit (ICU). Non-invasive methods that are mostly based on auscultation or cuff oscillometric principles do provide relatively accurate measurement of blood pressure. However, they mostly involve physical inconveniences such as pressure or stress on the human body. Here, we introduce a new non-invasive mechanism of tissue-informative measurement, where an experimental phenomenon called subcutaneous tissue pressure equilibrium is revealed and related for application in detection of absolute blood pressure. A prototype was experimentally verified to provide an absolute blood pressure measurement by wearing a watch-type measurement module that does not cause any discomfort. This work is supposed to contribute remarkably to the advancement of continuous non-invasive mobile devices for 24-7 daily-life ambulatory blood-pressure monitoring.
authors.affiliation: UMEDIX Corporation Limited, Seoul, Republic of Korea.
authors.forename: Sung Hun
authors.initials: SH
authors.lastname: Woo
authors.affiliation: UMEDIX Corporation Limited, Seoul, Republic of Korea.
authors.forename: Yun Young
authors.initials: YY
authors.lastname: Choi
authors.affiliation: UMEDIX Corporation Limited, Seoul, Republic of Korea.
authors.forename: Dae Jung
authors.initials: DJ
authors.lastname: Kim
authors.affiliation: School of Electrical and Computer Engineering, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea.
authors.forename: Franklin
authors.initials: F
authors.lastname: Bien
authors.affiliation: School of Electrical and Computer Engineering, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea.
authors.forename: Jae Joon
authors.initials: JJ
authors.lastname: Kim
mesh_terms: D001794:Blood Pressure; D015924:Blood Pressure Monitors; D006801:Humans