title: Design and Rationale of Gulf locals with Acute Coronary Syndrome Events (Gulf Coast) Registry.
abstract: OBJECTIVE
  To describe the risk profile, management and one-year outcomes of patients hospitalized with acute coronary syndrome (ACS) in the Gulf region of the Middle East.
  
  
  METHODS
  The Gulf locals with acute coronary syndrome events (Gulf COAST) registry is a prospective, multinational, longitudinal, observational, cohort-based registry of consecutive citizens, from the Gulf region of the Middle East, admitted from January 2012 to January 2013 to 29 hospitals with a diagnosis of ACS. Data entered online included patient demographics, cardiovascular risk profiles, past medical history, physical findings on admission, in-hospital diagnostic tests and therapeutic management, as well as one year outcomes.
  
  
  RESULTS
  3188 patients were recruited. The mean age was 60.4 ± 12.6years (range: 22-112), 2104 (66%) were males and 1084 (34%) females. The discharge diagnosis was ST-segment elevation myocardial infarction (STEMI) in 741 (23.2%), new-onset left bundle branch block myocardial infarction (LBBBMI) in 30 (0.9%), non-ST-segment elevation myocardial infarction (NSTEMI) in 1486 (46.6%) and unstable angina in 931 (29.2%). At hospital presentation, 2105 (66%), 1779 (55.8%), 1703 (53.4%) and 740 (23.2%) had history of hypertension, dyslipidemia, diabetes mellitus and active smoking, respectively.
  
  
  CONCLUSIONS
  Patients with ACS in our region are young with very high risk profile. The Gulf COAST registry is an example of successful regional collaboration and will provide information on contemporary management of ACS in the region.
authors.affiliation: Department of Medicine, Faculty of Medicine, Kuwait University, Kuwait.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Zubaid
authors.affiliation: Salmaniya Medical Complex, Cardiology Unit, Manama, Bahrain.
authors.forename: Khalid Bin
authors.initials: KB
authors.lastname: Thani
authors.affiliation: Department of Medicine, Mubarak Al-Kabeer Hospital, Ministry of Health, Kuwait.
authors.forename: Wafa
authors.initials: W
authors.lastname: Rashed
authors.affiliation: Heart and Vascular Institute, Sheikh Khalifa Medical City, Abu Dhabi, UAE; and Tufts University School of Medicine, Boston, MA, USA.
authors.forename: Alawi
authors.initials: A
authors.lastname: Alsheikh-Ali
authors.affiliation: Royal Hospital, Muscat, Oman.
authors.forename: Najib
authors.initials: N
authors.lastname: Alrawahi
authors.affiliation: Department of Medicine, Al-Adan, Ministry of Health, Kuwait.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Ridha
authors.affiliation: Department of Medicine, Al-Sabah, Ministry of Health, Kuwait.
authors.forename: Mousa
authors.initials: M
authors.lastname: Akbar
authors.affiliation: Department of Medicine, Al-Sabah, Ministry of Health, Kuwait.
authors.forename: Fahad
authors.initials: F
authors.lastname: Alenezi
authors.affiliation: Department of Medicine, Al-Jahra, Ministry of Health, Kuwait.
authors.forename: Rashed
authors.initials: R
authors.lastname: Alhamdan
authors.affiliation: Institute of Cardiac Science, Sheikh Khalifa Medical City.
authors.forename: Wael
authors.initials: W
authors.lastname: Almahmeed
authors.affiliation: Tawam Hospital. Alain, UAE.
authors.forename: Hussam
authors.initials: H
authors.lastname: Ouda
authors.affiliation: Dubai Hospital, Dubai Health Authority, Dubai,UAE.
authors.forename: Arif
authors.initials: A
authors.lastname: Al-Mulla
authors.affiliation: Rashid Hospital, Dubai, UAE.
authors.forename: Fahad
authors.initials: F
authors.lastname: Baslaib
authors.affiliation: Alain Hospital, Alain,UAE.
authors.forename: Abdulla
authors.initials: A
authors.lastname: Shehab
authors.affiliation: Zayed Military Hospital, Abu Dhabi, UAE.
authors.forename: Abdulla
authors.initials: A
authors.lastname: Alnuaimi
authors.affiliation: Mohamed Bin Khalifa Cardiac Center.
authors.forename: Haitham
authors.initials: H
authors.lastname: Amin
authors.affiliation: Yale University School of Medicine, New Haven, Connecticut, USA.
authors.forename: Harlan M
authors.initials: HM
authors.lastname: Krumholz
keywords: Acute coronary syndromes; Gulf; Middle East; registries.