title: [Clinical analysis and literature review of primary melanoma in nasal cavity and sinus--report of 9 cases].
abstract: OBJECTIVE
  To analyze and summarize clinical characteristic, treatment scheme and survival rate of primary melanom in nasal cavity and sinus.
  
  
  METHODS
  We retrospectively analyzed the 9 patients with primary melanom in nasal cavity and sinus who in data proceed were treated and reviewed the related literature.
  
  
  RESULTS
  Among the 9 patients, the clinical main symptoms are rhinostegnosis of lateral nasal and intermittent nasal bleeding. Pathologic examination is mainly characterized by tumor cells abnormity and cytoplasm containing pigment or without pigment, and main diagnosis basis is some or all of the positive for HMB45, S-100, melan-A. The survival rate are 88.9% (8/9) of 1-year, 66.7% (6/9) of 3-year and 33.3% (3/9) of 5-year.
  
  
  CONCLUSIONS
  The incidence of primary melanom in nasal cavity and sinusis is not frequent in clinic and confirmed by immunohistochemical. The extensive radical excision of focus and combine adjuvant radiotherapy postoperative may improve the survival rate of patients.
authors.forename: Lihua
authors.initials: L
authors.lastname: Rao
authors.forename: Xiandeng
authors.initials: X
authors.lastname: Li
authors.forename: Pingping
authors.initials: P
authors.lastname: Cao
authors.forename: Xiaowen
authors.initials: X
authors.lastname: Huang
authors.forename: Zheng
authors.initials: Z
authors.lastname: Liu
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis / Q000601:surgery; D008875:Middle Aged; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000175:diagnosis / Q000601:surgery; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis / Q000601:surgery; D012189:Retrospective Studies