title: First-trimester crown-rump length affects birth size symmetrically.
abstract: OBJECTIVE
  To investigate the relationship between crown-rump length (CRL) and birth weight, length and head circumference of the newborn.
  
  
  METHODS
  From a database of delivery records of 12,000 pregnancies, we identified 999 women with singleton pregnancies who had no medical problems, a normal menstrual history and a first trimester ultrasound scan in which CRL had been measured. All of the pregnancies resulted in live births without evidence of chromosomal and congenital abnormalities. The population in this study was divided into three groups according to CRL measurement; Group A (smaller-than-expected CRL), Group B (normal CRL) and Group C (larger-than-expected CRL).
  
  
  RESULTS
  The incidence of low birth weight infant was higher in Group A than in Group C (p = 0.010). The rate of small for gestational age (SGA) infants was similar between groups. The number of macrosomic or large for gestational age (LGA) infants was higher in Group C than Groups A and B. Both birth head circumference and length of infant were greater in Group C than Groups A and B. No significant difference for ponderal index value was observed between the groups (p = 0.927).
  
  
  CONCLUSIONS
  The growth pattern in the first trimester affects neonatal birth weight and length symmetrically without changing the ponderal index.
authors.affiliation: a Department of Obstetrics and Gynecology , Bursa Şevket Yılmaz Research and Education Hospital , Bursa , Turkey and.
authors.forename: Emin
authors.initials: E
authors.lastname: Ustunyurt
authors.affiliation: a Department of Obstetrics and Gynecology , Bursa Şevket Yılmaz Research and Education Hospital , Bursa , Turkey and.
authors.forename: Harun
authors.initials: H
authors.lastname: Simsek
authors.affiliation: a Department of Obstetrics and Gynecology , Bursa Şevket Yılmaz Research and Education Hospital , Bursa , Turkey and.
authors.forename: Barış
authors.initials: B
authors.lastname: Korkmaz
authors.affiliation: b Department of Perinatology , Dr Zekai Tahir Burak Research and Training Hospital , Ankara , Turkey.
authors.forename: Cantekin
authors.initials: C
authors.lastname: Iskender
mesh_terms: D000328:Adult; D001724:Birth Weight; D001827:Body Height; D015331:Cohort Studies; D018568:Crown-Rump Length; D005260:Female; D005320:Fetal Macrosomia / Q000453:epidemiology; D005865:Gestational Age; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D012189:Retrospective Studies; D016216:Ultrasonography, Prenatal
keywords: Birthweight; crown-rump length; first trimester; ponderal index