title: The relation between total joint arthroplasty and risk for serious cardiovascular events in patients with moderate-severe osteoarthritis: propensity score matched landmark analysis.
abstract: OBJECTIVE
  What are the rates of serious cardiovascular events in those who undergo primary total joint arthroplasty (TJA) compared with those who do not within three years of initial assessment?
  
  
  CONCLUSIONS
  Undergoing elective primary TJA within three years of initial assessment was associated with a significant 12.4% absolute reduction in subsequent risk of serious cardiovascular events.
  
  
  BACKGROUND
  Osteoarthritis is associated with increased mortality, particularly secondary to cardiovascular disease, with the risk for mortality proportional to the degree of disability secondary to the arthritis. This study suggests that management of hip or knee osteoarthritis with arthroplasty decreases the risk for subsequent serious cardiovascular events.
authors.affiliation: Division of Orthopaedic Surgery, Department of Surgery, University of Toronto, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Canada Women's College Research Institute, Women's College Hospital, Toronto, Canada.
authors.forename: Bheeshma
authors.initials: B
authors.lastname: Ravi
authors.affiliation: Institute for Clinical Evaluative Sciences, Toronto, Canada.
authors.forename: Ruth
authors.initials: R
authors.lastname: Croxford
authors.affiliation: Institute of Health Policy, Management and Evaluation, University of Toronto, Canada Institute for Clinical Evaluative Sciences, Toronto, Canada.
authors.forename: Peter C
authors.initials: PC
authors.lastname: Austin
authors.affiliation: Institute of Health Policy, Management and Evaluation, University of Toronto, Canada Women's College Research Institute, Women's College Hospital, Toronto, Canada Department of Medicine, University of Toronto, Canada.
authors.forename: Lorraine
authors.initials: L
authors.lastname: Lipscombe
authors.affiliation: Institute of Health Policy, Management and Evaluation, University of Toronto, Canada Institute for Clinical Evaluative Sciences, Toronto, Canada Department of Medicine, University of Toronto, Canada Lawrence S Bloomberg Faculty of Nursing, University of Toronto, Canada.
authors.forename: Arlene S
authors.initials: AS
authors.lastname: Bierman
authors.affiliation: Women's College Research Institute, Women's College Hospital, Toronto, Canada Department of Medicine, University of Toronto, Canada.
authors.forename: Paula J
authors.initials: PJ
authors.lastname: Harvey
authors.affiliation: Institute of Health Policy, Management and Evaluation, University of Toronto, Canada Women's College Research Institute, Women's College Hospital, Toronto, Canada Institute for Clinical Evaluative Sciences, Toronto, Canada Department of Medicine, University of Toronto, Canada Division of Rheumatology, Department of Medicine, Women's College Hospital, Toronto, Canada.
authors.forename: Gillian A
authors.initials: GA
authors.lastname: Hawker