title: Homologous whole blood transfusion during treatment of severe anemia in a chimpanzee (Pan troglodytes).
abstract: A 12-yr-old female chimpanzee (Pan troglodytes) was presented as severely emaciated and with generalized muscle weakness. Hematology and biochemistry revealed severe anemia and hypokalemia. The chimpanzee was treated supportively and symptomatically; although initially stable, the animal deteriorated rapidly on day 5, becoming depressed and jaundiced with further deterioration of anemia. To address the decline, a prompt transfusion of compatible and cross-matched fresh whole blood from a healthy adult male chimpanzee was administered over 120 min. During transfusion, an immediate reduction in the recipient's tachycardia was noted and substantial clinical improvement continued over 24 hr posttransfusion; no adverse transfusion reactions were observed.
authors.forename: John James
authors.initials: JJ
authors.lastname: Debenham
authors.forename: Rebeca
authors.initials: R
authors.lastname: Atencia
mesh_terms: D000740:Anemia / Q000628:therapy / Q000662:veterinary*; D000818:Animals; D018420:Ape Diseases / Q000628:therapy*; D001782:Blood Donors; D001803:Blood Transfusion / Q000662:veterinary*; D005260:Female; D008297:Male; D002679:Pan troglodytes