title: [Long-term results of postoperative electronic irradiation for 53 patients with keloids].
abstract: OBJECTIVE
  To analyze the results of postoperative radiotherapy with electronic beam for patients with keloids in our hospital.
  
  
  METHODS
  From September 2006 to May 2009, radiotherapy was given within 24 hours after operation in 53 keloid patients. With single vertical field irradiation, 6-12 Mev electronic beams of Linear Accelerator were selected for different incision depth in different sites. The field size was 1.0 cm (range: 0.5-2.0 cm) away from both incision ends and 1.25 cm (range: 0.75-2.50 cm) away from incision laterally. The radiation was given daily with median treatment course of 4 days (range: 3-21 days) at 3.5 Gy/Fx to a median total dose of 14 Gy (range: 8-20 Gy). SPSS 21. 0 was used for analysis.
  
  
  RESULTS
  All postoperative incisions healed in one stage, the median follow-up was 34 months (range: 18-63 months). The overall local control rate was 79.7%. For patients who received the dose of more than 14 Gy versus less than 14 Gy, the local control rate was 81.6%, 75.2%, respectively (P > 0.05). For male and female, the 3 year local recurrence rate were 45.3%, 9.9% respectively (P = 0.008). Multivariate analysis showed that the sex (male versus female) was an independent prognostic factor (P = 0.036).
  
  
  CONCLUSIONS
  Surgery combined with electronic beam irradiation is a rather effective way to treat keloids. The local control rate would have a better trend if the total dose was higher than 14 Gy. Sex is an independent prognostic factor.
authors.forename: Ling
authors.initials: L
authors.lastname: Rong
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Wu
authors.forename: Yanli
authors.initials: Y
authors.lastname: Hou
authors.forename: Xiumei
authors.initials: X
authors.lastname: Ma
authors.forename: Ming
authors.initials: M
authors.lastname: Ye
authors.forename: Yongrui
authors.initials: Y
authors.lastname: Bai
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007627:Keloid / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D016896:Treatment Outcome; D055815:Young Adult