title: Identification and characterization of a novel HLA-A allele, HLA-A*68:105, by genomic sequencing.
abstract: A novel HLA-A allele, HLA-A*68:105, was detected by sequence-based typing (SBT) in an Italian bone marrow donor. It differs from HLA-A*68:01:02 at five nucleotides, three intronic, nt 699 T->G (intron 2), nt 705 T->C (intron 2) and nt 2770 G->A (intron 7), and two located in exon 3, at positions 726 A-G (codon 94 Ile->Val) and 733 T-G (codon 97 Arg->Met), respectively.
authors.affiliation: Laboratorio di Immunogenetica, U.O. Medicina Trasfusionale e Biologia dei Trapianti, AOUP, Pisa, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Curcio
authors.forename: S
authors.initials: S
authors.lastname: Presciuttini
authors.forename: R
authors.initials: R
authors.lastname: Sciarrino
authors.forename: S
authors.initials: S
authors.lastname: Fornaciari
authors.forename: M L
authors.initials: ML
authors.lastname: Mariotti
authors.forename: F
authors.initials: F
authors.lastname: Scatena
mesh_terms: D000483:Alleles; D001483:Base Sequence; D005091:Exons / Q000235:genetics; D015894:Genome, Human / Q000235:genetics*; D015234:HLA-A Antigens / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA
chemical_list: D015234:HLA-A Antigens; C053029:HLA-A*68 antigen