title: [Incidence of chronic myeloid leukemia in 6 regions of Russia according to the data of the 2009-2012 population-based study].
abstract: OBJECTIVE
  To assess the main epidemiological characteristics of chronic myeloid leukemia (CML) in the Russian Federation.
  
  
  METHODS
  A planned epidemiological prospective study was conducted in 2009-2012 in 6 Russian regions with the total number of 10.1 million inhabitants, which notified all new CML cases.
  
  
  RESULTS
  The unstandardized (unnormalized, baseline) recorded incidence of CML in the examined regions was 0.58 per 100,000 annually. Its standardized (normalized) incidence was 0.70 for the WHO standard population and 0.72 for the European standard population. The regional variations in the incidence were 0.44 to 0.69. The structural analysis of the incidence in the age strata indicated that the overall morbidity was less due to the decreased rate of registration in old age groups. The morbidity rates in patients aged less than 60 years were nearly similar to the European rates; those in patients aged over 70 years were almost 10 times lower. The lower rate of detection and screening diagnosis of CML in pensioners in primary health care is discussed.
  
  
  CONCLUSIONS
  The data obtained in this study may serve as the starting point for monitoring the CML epidemiological situation.
authors.forename: S M
authors.initials: SM
authors.lastname: Kulikov
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Vinogradova
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Chelysheva
authors.forename: I A
authors.initials: IA
authors.lastname: Tishchenko
authors.forename: M A
authors.initials: MA
authors.lastname: Galaĭko
authors.forename: O V
authors.initials: OV
authors.lastname: Lazareva
authors.forename: O M
authors.initials: OM
authors.lastname: Senderova
authors.forename: V M
authors.initials: VM
authors.lastname: Pepeliaeva
authors.forename: S V
authors.initials: SV
authors.lastname: Meresiĭ
authors.forename: A S
authors.initials: AS
authors.lastname: Luchinin
authors.forename: V A
authors.initials: VA
authors.lastname: Ovsepian
authors.forename: G I
authors.initials: GI
authors.lastname: Miliutina
authors.forename: L V
authors.initials: LV
authors.lastname: Gavrilova
authors.forename: L B
authors.initials: LB
authors.lastname: Avdeeva
authors.forename: A L
authors.initials: AL
authors.lastname: Neverova
authors.forename: A G
authors.initials: AG
authors.lastname: Turkina
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D006801:Humans; D015994:Incidence; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D008875:Middle Aged; D012042:Registries; D012426:Russia / Q000453:epidemiology