title: Incretin based therapy in the management of steroid induced diabetes mellitus.
abstract: Corticosteroid-induced hyperglycemia is a common medical problem which can cause frequent hospitalizations and therefore relates to an increase in morbidity. Metformin, sulfonylureas, thiazolidinediones and insulin are well known available therapies for the treatment of steroid induced hyperglycemia. Incretin based therapies are a newly developing strategies with a considerable importance in the treatment regimen as well. This review aims at discussing the pathophysiology of steroid induced hyperglycemia in addition to the available therapies used for treatment, focusing on incretin therapies.
authors.forename: Sarah
authors.initials: S
authors.lastname: El Ghandour
authors.affiliation: Department of Internal Medicine, Division of Endocrinology and Metabolism, American University of Beirut, Lebanon. sazar@aub.edu.lb.
authors.forename: Sami
authors.initials: S
authors.lastname: Azar
mesh_terms: D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D001786:Blood Glucose; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000139:chemically induced / Q000517:prevention & control*; D004305:Dose-Response Relationship, Drug; D006760:Hospitalization; D006801:Humans; D006943:Hyperglycemia / Q000097:blood / Q000139:chemically induced*; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D054795:Incretins / Q000097:blood / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D001786:Blood Glucose; D007004:Hypoglycemic Agents; D054795:Incretins