title: Structure and antioxidant activity of phenolic compounds isolated from the edible fruits and stem bark of Harpephyllum caffrum.
abstract: Antioxidant activity in edible fruits is an important characteristic in the choice of fruits for human consumption, and has profound influence on nutrition and health. Two pharmacologically active triterpenoids, β-sitosterol and lupeol, and the powerful flavan-3-ol antioxidant, (+)-catechin, were isolated from the edible fruits of Harpephyllum caffrum while a mixture of cardanols, an alkyl p-coumaric acid ester, and (+)-catechin were isolated from the stem bark. This is the first report of these compounds being isolated from this plant. The antioxidant capacity of (+)-catechin was higher than the other isolated compounds as well as the known antioxidant, ascorbic acid.
authors.affiliation: a School of Chemistry and Physics , University of KwaZulu-Natal (UKZN) , Durban , South Africa.
authors.forename: Roshila
authors.initials: R
authors.lastname: Moodley
authors.forename: Neil A
authors.initials: NA
authors.lastname: Koorbanally
authors.forename: Md
authors.initials: M
authors.lastname: Shahidul Islam
authors.forename: Sreekanth B
authors.initials: SB
authors.lastname: Jonnalagadda
mesh_terms: D027926:Anacardiaceae / Q000737:chemistry*; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification*; D003373:Coumaric Acids / Q000302:isolation & purification / Q000494:pharmacology; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005638:Fruit / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D053978:Pentacyclic Triterpenes / Q000302:isolation & purification / Q000494:pharmacology; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D024301:Plant Bark / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D011422:Propionates; D012855:Sitosterols / Q000302:isolation & purification / Q000494:pharmacology; D000094042:Lupanes
chemical_list: D000975:Antioxidants; D003373:Coumaric Acids; D005419:Flavonoids; D053978:Pentacyclic Triterpenes; D010636:Phenols; D011422:Propionates; D012855:Sitosterols; C404987:flavan-3-ol; C025473:gamma-sitosterol; C495469:p-coumaric acid; C010480:lupeol; D000094042:Lupanes
keywords: (+)-catechin; Harpephyllum caffrum; antioxidant activity; cardanol; coumarate; medicinal value