title: Hemophagocytic syndrome in severe dengue Fever: a rare presentation.
abstract: We describe a 2-year old boy developing virus-associated hemophagocytic syndrome in severe dengue fever. The condition was diagnosed according to the established criteria of the International Histiocyte Society. There was uneventful recovery with corticosteroid therapy. Secondary hemophagocytosis in children can mimic severe sepsis, systemic inflammatory response syndrome, or multi organ dysfunction syndrome and lead to diagnostic difficulties. This report adds to the limited pediatric cases of dengue related hemophagocytic syndrome reported in literature; and underlines the importance of prompt diagnosis and appropriate treatment of this rare but serious complication.
authors.affiliation: Department of Pathology, Advanced Medicare and Research Institute, 223, 230 Barkohala Lane, Mukundapur, Kalikapur, Kolkata, 700099 West Bengal India.
authors.forename: Subhashis
authors.initials: S
authors.lastname: Mitra
authors.affiliation: Department of Pediatrics, Advanced Medicare and Research Institute, Kolkata, India.
authors.forename: Rajat
authors.initials: R
authors.lastname: Bhattacharyya
keywords: Dengue; Hemophagocytic lymphohistiocytosis; Hemophagocytic syndrome