title: Rh(III)-catalyzed dual directing group assisted sterically hindered C-H bond activation: a unique route to meta and ortho substituted benzofurans.
abstract: A new strategy for the synthesis of highly substituted benzofurans from meta-substituted hydroxybenzenes and alkynes via a rhodium(III)-catalyzed activation of a sterically hindered C-H bond is demonstrated. A possible mechanism involving dual directing group assisted ortho C-H bond activation is proposed.
authors.affiliation: Department of Chemistry, National Tsing Hua University, Hsinchu 30013, Taiwan. chcheng@mx.nthu.edu.tw.
authors.forename: Chien-Hung
authors.initials: CH
authors.lastname: Yeh
authors.forename: Wei-Chen
authors.initials: WC
authors.lastname: Chen
authors.forename: Parthasarathy
authors.initials: P
authors.lastname: Gandeepan
authors.forename: Ya-Chun
authors.initials: YC
authors.lastname: Hong
authors.forename: Cheng-Hung
authors.initials: CH
authors.lastname: Shih
authors.forename: Chien-Hong
authors.initials: CH
authors.lastname: Cheng
mesh_terms: D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D006860:Hydrogen Bonding; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*
chemical_list: D001572:Benzofurans; D012238:Rhodium