title: Effect of ABO blood type on ovarian reserve in Chinese women.
abstract: OBJECTIVE
  To explore the effect of ABO blood type on ovarian reserve in Chinese women.
  
  
  METHODS
  Retrospective analysis.
  
  
  METHODS
  University-affiliated IVF center.
  
  
  METHODS
  The retrospective analysis involved 35,479 women who underwent in vitro fertilization and embryo transfer (IVF-ET) cycles between 2006 and 2012.
  
  
  METHODS
  None.
  
  
  METHODS
  The association between ABO blood types and diminished ovarian reserve (DOR).
  
  
  RESULTS
  Among 35,479 Chinese women, 11,395 (32.12%) had blood type B, 10,583 (29.83%) had blood type O, 9,861 (27.79%) had blood type A, and 3,640 (10.26%) had blood type AB. There was a statistically significantly higher percentage of blood type O among those with follicle-stimulating hormone (FSH) levels ≤10 IU/L compared with those with FSH levels >10 IU/L. Conversely, among the women with DOR, there was statistically significantly higher percentage of those with blood types B and AB. Blood type A was not associated with DOR occurrence. Multivariate logistic regression analysis showed that blood type O was statistically significantly less often associated with DOR occurrence, whereas the B antigen (blood type B or AB) was statistically significantly associated with an increased risk of DOR.
  
  
  CONCLUSIONS
  Our results have shown that there is an association between ABO blood type and DOR occurrence in Chinese women. Women with blood type O were statistically significantly less likely to have DOR, whereas those with B antigen (blood type B or AB) were statistically significantly more likely to have DOR. Blood type A was not associated with ovarian reserve.
authors.affiliation: Reproductive Medical Center, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China.
authors.forename: Shengli
authors.initials: S
authors.lastname: Lin
authors.affiliation: Reproductive Medical Center, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China.
authors.forename: Rong
authors.initials: R
authors.lastname: Li
authors.affiliation: Reproductive Medical Center, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China.
authors.forename: Hongbin
authors.initials: H
authors.lastname: Chi
authors.affiliation: Reproductive Medical Center, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China.
authors.forename: Shuo
authors.initials: S
authors.lastname: Huang
authors.affiliation: Research Center of Clinical Epidemiology, Peking University Third Hospital, Beijing, People's Republic of China.
authors.forename: Hua
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Reproductive Medical Center, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China.
authors.forename: Xiaoying
authors.initials: X
authors.lastname: Zheng
authors.affiliation: Reproductive Medical Center, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China.
authors.forename: Ping
authors.initials: P
authors.lastname: Liu
authors.affiliation: Reproductive Medical Center, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China. Electronic address: jie.qiao@263.net.
authors.forename: Jie
authors.initials: J
authors.lastname: Qiao
mesh_terms: D000017:ABO Blood-Group System / Q000235:genetics* / Q000276:immunology; D000328:Adult; D044466:Asian People / Q000235:genetics; D002681:China / Q000453:epidemiology; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D007247:Infertility, Female / Q000453:epidemiology; D065851:Ovarian Reserve / Q000276:immunology*; D012189:Retrospective Studies
chemical_list: D000017:ABO Blood-Group System; D005640:Follicle Stimulating Hormone
keywords: Blood type; FSH; infertility; ovarian reserve