title: Using N-tosylhydrazone as a double nucleophile in the palladium-catalyzed cross-coupling reaction to synthesize allylic sulfones.
abstract: Without extra addition of sulfinate salt, allylic sulfones were synthesized by palladium-catalyzed cross-coupling of aryl iodide with N-tosylhydrazone. In this transformation, not only the diazo compound but also the sulfinate salt, which were both generated in situ from base-mediated decomposition of the N-tosylhydrazone, was used as nucleophilic partner.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000 (P.R. China), Fax: (+86) 931-8912582.
authors.forename: Ping-Xin
authors.initials: PX
authors.lastname: Zhou
authors.forename: Yu-Ying
authors.initials: YY
authors.lastname: Ye
authors.forename: Lian-Biao
authors.initials: LB
authors.lastname: Zhao
authors.forename: Jian-Ye
authors.initials: JY
authors.lastname: Hou
authors.forename: Xing
authors.initials: X
authors.lastname: Kang
authors.forename: Dao-Qian
authors.initials: DQ
authors.lastname: Chen
authors.forename: Qian
authors.initials: Q
authors.lastname: Tang
authors.forename: Jie-Yu
authors.initials: JY
authors.lastname: Zhang
authors.forename: Qi-Xing
authors.initials: QX
authors.lastname: Huang
authors.forename: Lan
authors.initials: L
authors.lastname: Zheng
authors.forename: Jun-Wei
authors.initials: JW
authors.lastname: Ma
authors.forename: Peng-Fei
authors.initials: PF
authors.lastname: Xu
authors.forename: Yong-Min
authors.initials: YM
authors.lastname: Liang
mesh_terms: D000498:Allyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D006835:Hydrazones / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013450:Sulfones / Q000138:chemical synthesis* / Q000737:chemistry; D014105:Tosyl Compounds / Q000737:chemistry*
chemical_list: D000498:Allyl Compounds; D006835:Hydrazones; D013450:Sulfones; D014105:Tosyl Compounds; D010165:Palladium
keywords: atom economy; carbenes; double nucleophiles; palladium; tosylhydrazone