title: Optimisation of the imaging and dosimetric characteristics of an electronic portal imaging device employing plastic scintillating fibres using Monte Carlo simulations.
abstract: A Monte Carlo model of a novel electronic portal imaging device (EPID) has been developed using Geant4 and its performance for imaging and dosimetry applications in radiotherapy has been characterised. The EPID geometry is based on a physical prototype under ongoing investigation and comprises an array of plastic scintillating fibres in place of the metal plate/phosphor screen in standard EPIDs. Geometrical and optical transport parameters were varied to investigate their impact on imaging and dosimetry performance. Detection efficiency was most sensitive to variations in fibre length, achieving a peak value of 36% at 50 mm using 400 keV x-rays for the lengths considered. Increases in efficiency for longer fibres were partially offset by reductions in sensitivity. Removing the extra-mural absorber surrounding individual fibres severely decreased the modulation transfer function (MTF), highlighting its importance in maximising spatial resolution. Field size response and relative dose profile simulations demonstrated a water-equivalent dose response and thus the prototype's suitability for dosimetry applications. Element-to-element mismatch between scintillating fibres and underlying photodiode pixels resulted in a reduced MTF for high spatial frequencies and quasi-periodic variations in dose profile response. This effect is eliminated when fibres are precisely matched to underlying pixels. Simulations strongly suggest that with further optimisation, this prototype EPID may be capable of simultaneous imaging and dosimetry in radiotherapy.
authors.affiliation: School of Physics, University of Sydney, NSW, Australia. Ingham Institute for Applied Medical Research, Sydney, NSW, Australia.
authors.forename: S J
authors.initials: SJ
authors.lastname: Blake
authors.forename: A L
authors.initials: AL
authors.lastname: McNamara
authors.forename: P
authors.initials: P
authors.lastname: Vial
authors.forename: L
authors.initials: L
authors.lastname: Holloway
authors.forename: Z
authors.initials: Z
authors.lastname: Kuncic
mesh_terms: D003198:Computer Simulation; D055615:Electrical Equipment and Supplies / Q000592:standards*; D004867:Equipment Design; D006801:Humans; D008962:Models, Theoretical; D009010:Monte Carlo Method; D010969:Plastics; D011829:Radiation Dosage; D011856:Radiographic Image Enhancement / Q000295:instrumentation / Q000592:standards*; D011874:Radiometry / Q000295:instrumentation* / Q000379:methods; D015203:Reproducibility of Results; D012588:Scintillation Counting / Q000295:instrumentation*; D014963:X-Ray Intensifying Screens
chemical_list: D010969:Plastics