title: [Cellular and humoral immunity in rats with atopic dermatitis].
abstract: We studied indicators of systemic and local immunity in rats with allergic dermatitis (Ig A, E, G, M, CIC, CD3, CD4, CD8, SD 19, SD56). In rats with allergic dermatitis on the local level, the most active is humoral immunity. One of the pathogenesis of atopic dermatitis is an increased content of circulating immune complexes in the blood and decreased T-helper in a total amount of T- lymphocytes. An informative index with a high level of correlation is the IgE level, confirming the advisability of its determination in blood plasma in acute dermatitis to characterize lymphocyte apoptosis markers and prognosis of the disease. An established negative correlation between the concentrations of SD95-marker of apoptosis and the IgE level in healthy and sick animals may point for involvement of apoptosis in the regulation of the total IgE.
authors.forename: A I
authors.initials: AI
authors.lastname: Berezniakova
authors.forename: V F
authors.initials: VF
authors.lastname: Cheremisina
authors.forename: O D
authors.initials: OD
authors.lastname: Zhemela
mesh_terms: D000818:Animals; D000936:Antigen-Antibody Complex / Q000097:blood / Q000276:immunology; D017209:Apoptosis / Q000276:immunology; D001402:B-Lymphocytes / Q000166:cytology / Q000276:immunology; D015415:Biomarkers / Q000097:blood; D003876:Dermatitis, Atopic / Q000276:immunology* / Q000473:pathology; D007111:Immunity, Cellular; D056724:Immunity, Humoral; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology; D008297:Male; D051381:Rats; D006377:T-Lymphocytes, Helper-Inducer / Q000166:cytology / Q000276:immunology; D019014:fas Receptor / Q000097:blood / Q000276:immunology
chemical_list: D000936:Antigen-Antibody Complex; D015415:Biomarkers; D019014:fas Receptor; D007073:Immunoglobulin E