title: Assessment of knee joint pain in experimental rodent models of osteoarthritis.
abstract: Pain assessment in animal models of osteoarthritis is integral to interpretation of a model's utility in representing the clinical condition, and enabling accurate translational medicine. Here we describe two methods for behavioral pain assessments available for use in animal models of experimental osteoarthritic pain: Von Frey filaments and spontaneous activity monitoring.
authors.affiliation: Comparative Medicine Consultants, Chicago, IL, 60631, USA.
authors.forename: Margaret J
authors.initials: MJ
authors.lastname: Piel
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Kroin
authors.forename: Hee-Jeong
authors.initials: HJ
authors.lastname: Im
mesh_terms: D000818:Animals; D001169:Arthritis, Experimental / Q000503:physiopathology*; D006801:Humans; D051379:Mice; D020370:Osteoarthritis, Knee / Q000503:physiopathology*; D010147:Pain Measurement / Q000379:methods*