title: Selective palladium-catalyzed aminocarbonylation of 1,3-dienes: atom-efficient synthesis of β,γ-unsaturated amides.
abstract: Carbonylation reactions constitute important methodologies for the synthesis of all kinds of carboxylic acid derivatives. The development of novel and efficient catalysts for these transformations is of interest for both academic and industrial research. Here, the first palladium-based catalyst system for the aminocarbonylation of 1,3-dienes is described. This atom-efficient transformation proceeds under additive-free conditions and provides straightforward access to a variety of β,γ-unsaturated amides in good to excellent yields, often with high selectivities.
authors.affiliation: Leibniz-Institut für Katalyse e.V., an der Universität Rostock , Albert-Einstein-Str. 29a, 18059 Rostock, Germany.
authors.forename: Xianjie
authors.initials: X
authors.lastname: Fang
authors.forename: Haoquan
authors.initials: H
authors.lastname: Li
authors.forename: Ralf
authors.initials: R
authors.lastname: Jackstell
authors.forename: Matthias
authors.initials: M
authors.lastname: Beller