title: Mobile health, exercise and metabolic risk: a randomized controlled trial.
abstract: BACKGROUND
  It was hypothesized that a mobile health (mHealth) intervention would elicit greater improvements in systolic blood pressure and other cardiometabolic risk factors at 12 weeks, which would be better maintained over 52 weeks, compared to the active control intervention.
  
  
  METHODS
  Eligible participants (≥2 metabolic syndrome risk factors) were randomized to the mHealth intervention (n = 75) or the active control group (n = 74). Blood pressure and other cardiometabolic risk factors were measured at baseline and at 12, 24 and 52 weeks. Both groups received an individualized exercise prescription and the intervention group additionally received a technology kit for home monitoring of biometrics and physical activity.
  
  
  RESULTS
  Analyses were conducted on 67 participants in the intervention group (aged 56.7 ± 9.7 years; 71.6% female) and 60 participants in the active control group (aged 59.1 ± 8.4 years; 76.7% female). At 12 weeks, baseline adjusted mean change in systolic blood pressure (primary outcome) was greater in the active control group compared to the intervention group (-5.68 mmHg; 95% CI -10.86 to -0.50 mmHg; p = 0.03), but there were no differences between groups in mean change for secondary outcomes. Over 52-weeks, the difference in mean change for systolic blood pressure was no longer apparent between groups, but remained significant across the entire population (time: p < 0.001).
  
  
  CONCLUSIONS
  In participants with increased cardiometabolic risk, exercise prescription alone had greater short-term improvements in systolic blood pressure compared to the mHealth intervention, though over 52 weeks, improvements were equal between interventions.
  
  
  BACKGROUND
  ClinicalTrials.gov http://NCT01944124.
authors.affiliation: Western University, Department of Family Medicine, Centre for Studies in Family Medicine, Western Centre for Public Health and Family Medicine, (2nd Floor), 1151 Richmond St,, London, Ontario N6A 3K7, Canada. petrella@uwo.ca.
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Petrella
authors.forename: Melanie I
authors.initials: MI
authors.lastname: Stuckey
authors.forename: Sheree
authors.initials: S
authors.lastname: Shapiro
authors.forename: Dawn P
authors.initials: DP
authors.lastname: Gill
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure; D002318:Cardiovascular Diseases / Q000517:prevention & control; D015444:Exercise; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000517:prevention & control*; D008875:Middle Aged; D017010:Reminder Systems; D012306:Risk; D012307:Risk Factors; D017216:Telemedicine / Q000379:methods*; D060145:Text Messaging