title: Progress in development of an integrated dietary supplement ingredient database at the NIH Office of Dietary Supplements.
abstract: Several activities of the Office of Dietary Supplements (ODS) at the National Institutes of Health involve enhancement of dietary supplement databases. These include an initiative with US Department of Agriculture to develop an analytically substantiated dietary supplement ingredient database (DSID) and collaboration with the National Center for Health Statistics to enhance the dietary supplement label database in the National Health and Nutrition Examination Survey (NHANES). The many challenges that must be dealt with in developing an analytically supported DSID include categorizing product types in the database, identifying nutrients, and other components of public health interest in these products and prioritizing which will be entered in the database first. Additional tasks include developing methods and reference materials for quantifying the constituents, finding qualified laboratories to measure the constituents, developing appropriate sample handling procedures, and finally developing representative sampling plans. Developing the NHANES dietary supplement label database has other challenges such as collecting information on dietary supplement use from NHANES respondents, constant updating and refining of information obtained, developing default values that can be used if the respondent cannot supply the exact supplement or strength that was consumed, and developing a publicly available label database. Federal partners and the research community are assisting in making an analytically supported dietary supplement database a reality.
authors.affiliation: Office of Dietary Supplements, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892, USA.
authors.forename: Johanna T
authors.initials: JT
authors.lastname: Dwyer
authors.affiliation: Office of Dietary Supplements, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892, USA.
authors.forename: Mary Frances
authors.initials: MF
authors.lastname: Picciano
authors.affiliation: Dietary Supplement Methods and Reference Materials Program, Office of Dietary Supplements, National Institutes of Health, USA.
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Betz
authors.affiliation: Office of Dietary Supplements, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892, USA.
authors.forename: Kenneth D
authors.initials: KD
authors.lastname: Fisher
authors.affiliation: Office of Dietary Supplements, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892, USA.
authors.forename: Leila G
authors.initials: LG
authors.lastname: Saldanha
authors.affiliation: Office of Dietary Supplements, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892, USA.
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Yetley
authors.affiliation: Office of Dietary Supplements, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892, USA.
authors.forename: Paul M
authors.initials: PM
authors.lastname: Coates
authors.affiliation: National Health and Nutrition Examination Survey, National Center for Health Statistics, Centers for Disease Control, US Department of Health and Human Services, USA.
authors.forename: Kathy
authors.initials: K
authors.lastname: Radimer
authors.affiliation: National Health and Nutrition Examination Survey, National Center for Health Statistics, Centers for Disease Control, US Department of Health and Human Services, USA.
authors.forename: Bernadette
authors.initials: B
authors.lastname: Bindewald
authors.affiliation: National Institute of Standards and Technology, Gaithersburg, MD, USA.
authors.forename: Katherine E
authors.initials: KE
authors.lastname: Sharpless
authors.affiliation: Nutrient Data Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, MD, USA.
authors.forename: Joanne
authors.initials: J
authors.lastname: Holden
authors.affiliation: Nutrient Data Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, MD, USA.
authors.forename: Karen
authors.initials: K
authors.lastname: Andrews
authors.affiliation: Nutrient Data Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, MD, USA.
authors.forename: Cuiwei
authors.initials: C
authors.lastname: Zhao
authors.affiliation: Food Composition Laboratory, Agricultural Research Service, Beltsville Human Nutrition Research Center, US Department of Agriculture, Beltsville, MD, USA.
authors.forename: James
authors.initials: J
authors.lastname: Harnly
authors.affiliation: Food Composition Laboratory, Agricultural Research Service, Beltsville Human Nutrition Research Center, US Department of Agriculture, Beltsville, MD, USA.
authors.forename: Wayne R
authors.initials: WR
authors.lastname: Wolf
authors.affiliation: Research and Development Division, National Agricultural Statistic Service, US Department of Agriculture Fairfax, VA, USA.
authors.forename: Charles R
authors.initials: CR
authors.lastname: Perry
keywords: Analytical substantiation; Certified reference materials; DSID; Dietary supplement composition; Dietary supplement ingredient database; Dietary supplement labels; Dietary supplements; NHANES; Standard reference materials