title: Can we really diagnose diabetes during pregnancy?
abstract: OBJECTIVE
  To identify the accuracy of diagnosing postpartum diabetes and glucose intolerance using antepartum glycosylated hemoglobin (HbA1c) and fasting glucose values.
  
  
  METHODS
  A retrospective Hawaiian cohort of women with gestational diabetes during 2004-2011 were evaluated. Antepartum HbA1c and postpartum 75-g glucose tolerance tests were obtained.
  
  
  RESULTS
  An antepartum HbA1c value of ≥6.5% had a 45.7% sensitivity, a 96% specificity and a 40% positive predictive value (PPV) for predicting postpartum diabetes. An antepartum HbA1c value of ≥6.5% had a 6.6% sensitivity, a 94.2% specificity and a 27% PPV for predicting postpartum impaired glucose tolerance. An antepartum HbA1c value of ≥6.5% had a 10.3% sensitivity, a 95.7% specificity and a 33.3% PPV for predicting postpartum impaired fasting glucoses.
  
  
  CONCLUSIONS
  We could not demonstrate a clinically useful PPV for diagnosing postpartum diabetes or glucose intolerance using an antepartum elevated HbA1c value of ≥6.5% or a fasting glucose level of ≥90 mg/dL.
authors.forename: Janet M
authors.initials: JM
authors.lastname: Burlingame
authors.forename: Lisa
authors.initials: L
authors.lastname: Bartholomew
authors.forename: Teresa
authors.initials: T
authors.lastname: Brink-Wong
authors.forename: Sheila
authors.initials: S
authors.lastname: Sampaga
authors.forename: Timothy
authors.initials: T
authors.lastname: Dye
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D003920:Diabetes Mellitus / Q000175:diagnosis; D016640:Diabetes, Gestational / Q000097:blood*; D005215:Fasting; D005260:Female; D005951:Glucose Tolerance Test; D006442:Glycated Hemoglobin / Q000378:metabolism*; D006801:Humans; D049590:Postpartum Period; D011247:Pregnancy; D012189:Retrospective Studies
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin