title: Effect of suction on macular and retinal nerve fiber layer thickness during femtosecond lenticule extraction and femtosecond laser-assisted laser in situ keratomileusis.
abstract: OBJECTIVE
  To compare the effect of suction on macular and retinal nerve fiber layer thickness during femtosecond lenticule extraction and femtosecond laser-assisted laser in situ keratomileusis (LASIK) with the Visumax FS system.
  
  
  METHODS
  Ophthalmic Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China.
  
  
  METHODS
  Prospective comparative case series.
  
  
  METHODS
  Fourier-domain optical coherence tomography was used to measure macular and retinal nerve fiber layer thickness preoperatively and through 6 months postoperatively.
  
  
  RESULTS
  The study evaluated 196 eyes. In the femtosecond lenticule extraction group, the mean foveal, parafoveal, and perifoveal retinal thicknesses 1 day and 1 week postoperatively were diminished, although the changes were not statistically significant. The retinal thickness did not change significantly 1, 3, or 6 months postoperatively (P>.05). In the LASIK group, the mean foveal, parafoveal, and perifoveal retinal thicknesses did not change significantly at any postoperative timepoint (P>.05). The differences in all 3 retinal thicknesses between the 2 groups were not significant 1, 3, or 6 months postoperatively (P>.05). The ganglion cell complex and retinal nerve fiber layer thickness did not change significantly from preoperatively to any postoperative timepoint in either group (P>.05).
  
  
  CONCLUSIONS
  Suction had no significant clinical effects on the macular thickness and retinal nerve fiber layer during femtosecond lenticule extraction or femtosecond laser-assisted LASIK.
authors.affiliation: From the Ophthalmic Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
authors.affiliation: From the Ophthalmic Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China. Electronic address: crystalzj652@163.com.
authors.forename: Yuehua
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: From the Ophthalmic Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zheng
authors.affiliation: From the Ophthalmic Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Liu
authors.affiliation: From the Ophthalmic Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China.
authors.forename: Changbin
authors.initials: C
authors.lastname: Zhai
authors.affiliation: From the Ophthalmic Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China.
authors.forename: Yue
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000328:Adult; D003319:Corneal Stroma / Q000601:surgery*; D005583:Fourier Analysis; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D009216:Myopia / Q000601:surgery; D009412:Nerve Fibers; D009929:Organ Size; D011446:Prospective Studies; D012029:Refraction, Ocular / Q000502:physiology; D012160:Retina / Q000166:cytology*; D012165:Retinal Ganglion Cells / Q000166:cytology*; D013396:Suction; D013524:Surgical Flaps; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult