title: Sojourn in excessively high oxygen saturation ranges in individual, very low-birthweight neonates.
abstract: OBJECTIVE
  To investigate the variability in sojourn times at high oxygen saturations (SpO2 ) in individual patients and to examine whether there are subsets of patients or treatments that are associated with differing sojourn times at SpO2 ≥93%.
  
  
  METHODS
  Pulse oximetry data (Masimo) were studied in 71 premature babies receiving supplemental oxygen. Outcome measure was proportion of time per 12-h shift that individual babies spent in the range SpO2 ≥93%. We studied whether an inordinate proportion of time spent at SpO2 ≥93% was attributable to any subset of babies, mode of ventilation or nursing shifts, whether sojourn times were statistically independent shift-to-shift and whether an educational intervention reduced the amount of time spent at SpO2 ≥93%.
  
  
  RESULTS
  The proportion of time spent by the populations overall at SpO2 ≥93% was distributed equally among babies. However, high-frequency ventilation was associated with the least amount of time at SpO2 ≥93% compared with other modes of respiratory support (p < 0.0001), while nasal cannulae were associated with the highest proportion of time at SpO2 ≥93% (p < 0.001).
  
  
  CONCLUSIONS
  Measures to improve compliance with targeted SpO2 ranges should be applied universally although further improvement may be achieved by specifically targeting babies receiving supplemental oxygen via nasal cannula.
authors.affiliation: The Regional Neonatal Center, Maria Fareri Children's Hospital, New York Medical College, Valhalla, NY, USA.
authors.forename: Jenda
authors.initials: J
authors.lastname: Arawiran
authors.forename: JeanneMarie
authors.initials: J
authors.lastname: Curry
authors.forename: Lorna
authors.initials: L
authors.lastname: Welde
authors.forename: Gad
authors.initials: G
authors.lastname: Alpan
mesh_terms: D045422:Continuous Positive Airway Pressure / Q000706:statistics & numerical data*; D006612:High-Frequency Ventilation / Q000706:statistics & numerical data*; D006801:Humans; D052577:Infant, Extremely Low Birth Weight / Q000097:blood*; D062071:Infant, Extremely Premature / Q000097:blood*; D007231:Infant, Newborn; D010092:Oximetry; D010100:Oxygen / Q000008:administration & dosage / Q000097:blood*; D011446:Prospective Studies
chemical_list: D010100:Oxygen
keywords: Hyperoxia; Oximetry; Oxygen saturation; Premature infant