title: Pulmonary metastasectomy: review of experience at a tertiary cancer care center.
abstract: BACKGROUND
  Thirty to 40% of all extra thoracic cancers lead to secondary pulmonary lesions and approximately 20% of these cases feature metastases that are confined to the lungs. There is benefit of pulmonary metastasectomy in a select subset of patients.
  
  
  OBJECTIVE
  The goal of this study was to evaluate the patient profile, treatment patterns, and outcomes following surgical treatment of lung metastasis and to identify prognostic factors for long-term survival.
  
  
  METHODS
  Retrospective analysis of a prospectively maintained computerized database at a tertiary cancer care centre was done. 36 patients underwent curative resection for isolated pulmonary metastasis from January 1999 to December 2009. All metastasis were detected by non-contrast CT scan of the chest. Lung function tests were performed in all patients. Posterolateral thoracotomy was performed for resection of pulmonary metastasis by lung sparing procedures. A routine protocol of complete resection of all visible and palpable lung metastasis with a margin of 0.5 to 10 mm was followed in all patients. Staged thoracotomy was done for bilateral metastases. All palpable nodules were resected by wedge resection except in one case where pneumonectomy was done to achieve R0 resection. All patients underwent complete resection.
  
  
  CONCLUSIONS
  Disease-free interval of more than 1 year along with less than 2 malignant nodules in patients with non-visceral pulmonary metastasis are variables identified in the present study which have enabled pulmonary metastasectomy to be offered as a safe therapeutic lifeline to patients.
authors.forename: Suryanarayana S V
authors.initials: SS
authors.lastname: Deo
authors.forename: Nootan Kumar
authors.initials: NK
authors.lastname: Shukla
authors.affiliation: Department of Surgical Oncology, Dr BRA-IRCH, AIIMS, New Delhi, India.
authors.forename: Paras
authors.initials: P
authors.lastname: Khanna
authors.forename: Deepak
authors.initials: D
authors.lastname: Jha
authors.forename: Archit
authors.initials: A
authors.lastname: Pandit
authors.forename: Sanjay
authors.initials: S
authors.lastname: Thulkar
mesh_terms: D000328:Adult; D002173:Cancer Care Facilities; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D008297:Male; D059146:Metastasectomy / Q000009:adverse effects; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D062606:Tertiary Care Centers; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult