title: Endoscopic third ventriculostomy for post-inflammatory hydrocephalus in pediatric patients: is it worth a try?
abstract: Hydrocephalus is a very common disease in developing countries. Congenital aqueductal obstruction and post-inflammatory hydrocephalus come on the top of the list of causes of hydrocephalus. Till the recent introduction of cranial endoscopy and despite their frequent complications, shunts were considered as the mainstream treatment for this disease. Endoscopic third ventriculostomy (ETV), especially for obstructive hydrocephalus, introduced a new era of treatment that is free of lifetime shunt dependency. This study was done to assess the efficacy of ETV for treating post-inflammatory hydrocephalus in a unique group of patients thus preventing—if possible—the lifetime shunt dependency and suffering. ETV was tried as a first-line therapy in 35 children (23 males and 12 females) with hydrocephalus proved to be secondary to intracranial infection. Mean age was 9.2 months (4-15). Twenty-four patients (68.6%) were below the age of 6 months while 11 patients (31.4%) were above 6 months. Twenty-five patients (71.4%) had a head circumference of 3 cm and 10 patients (28.6%) had a 5 cm or more increase in the head circumference above the 95th percentile. All the patients included were followed postoperatively with regular clinical, computerized tomography (CT), and magnetic resonance imaging (MRI) examinations as well as cerebrospinal fluid (CSF) analysis and culture. The overall success of ETV was 55.9% (19/34). Nine (81.9%) out of the 11 patients that were endoscopically documented to have aqueductal obstruction showed improvement. While out of the 23 patients with patent aqueduct, only 10 patients (43.4%) had improved. Procedure-related complications were not encountered. CSF leakage from the surgical wound occurred in three patients and mild CSF infection occurred in one patient. ETV is a simple, safe, and effective method in treating not only obstructive hydrocephalus due to non-inflammatory etiology, but also post-inflammatory hydrocephalus especially when the aqueduct is obstructed. An overall 50% improvement in our study and even more in other series encourage the trial of getting rid of the lifetime shunt complications and suffering.
authors.affiliation: Department of Neurosurgery, Faculty of Medicine, Alexandria University, Champillion St., Elazaritta, Alexandria, Egypt.
authors.forename: Alaa
authors.initials: A
authors.lastname: Raouf
authors.forename: Ihab
authors.initials: I
authors.lastname: Zidan
authors.forename: Eshra
authors.initials: E
authors.lastname: Mohamed
mesh_terms: D002557:Cerebrospinal Fluid Shunts / Q000379:methods; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis / Q000601:surgery*; D007223:Infant; D007249:Inflammation / Q000150:complications; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D044583:Neuroendoscopy; D011183:Postoperative Complications / Q000473:pathology; D011184:Postoperative Period; D020542:Third Ventricle / Q000601:surgery*; D014696:Ventriculostomy / Q000379:methods