title: Relationship of left atrial global peak systolic strain with left ventricular diastolic dysfunction and brain natriuretic peptide level in patients presenting with non-ST elevation myocardial infarction.
abstract: BACKGROUND
  In patients presenting with non-ST elevation myocardial infarction, we investigated the relationship of left atrial deformational parameters evaluated by 2-dimensional speckle tracking imaging (2D-STI) with conventional echocardiographic diastolic dysfunction parameters and brain natriuretic peptide level.
  
  
  METHODS
  We enrolled 74 non-ST segment elevation myocardial infarction patients who were treated with percutaneous coronary intervention and 58 healthy control subjects. Non-ST segment elevation myocardial infarction patients had echocardiographic examination 48 h after the percutaneous coronary intervention procedure and venous blood samples were drawn simultaneously. In addition to conventional echocardiographic parameters, left atrial strain curves were obtained for each patient. Average peak left atrial strain values during left ventricular systole were measured.
  
  
  RESULTS
  BNP values were higher in non-ST segment elevation myocardial infarction patients compared to controls. Mean left atrium peak systolic global longitudinal strain in Group 2 (the control group) was higher than in the non-ST segment elevation myocardial infarction group. Left atrium peak systolic global longitudinal strain was significantly correlated with left ventricular ejection fraction. There was a significant inverse correlation between left atrium peak systolic global longitudinal strain and brain natriuretic peptide level, left atrium volume maximum, and left atrium volume minimum.
  
  
  CONCLUSIONS
  Our study shows that Left atrium peak systolic global longitudinal strain values decreased consistently with deteriorating systolic and diastolic function in non-ST segment elevation myocardial infarction patients treated with percutaneous coronary intervention. Left atrium peak systolic global longitudinal strain measurements may be helpful as a complimentary method to evaluate diastolic function in this patient population.
authors.affiliation: Department of Cardiology, Mengücek Gazi Education and Research Hospital, Erzincan University, Erzincan, Turkey.
authors.forename: Hüsnü
authors.initials: H
authors.lastname: Değirmenci
authors.affiliation: Department of Cardiology, Mengücek Gazi Education and Research Hospital, Erzincan University, Erzincan, Turkey.
authors.forename: Eftal Murat
authors.initials: EM
authors.lastname: Bakırcı
authors.affiliation: Department of Internal Medicine, Mengücek Gazi Education and Research Hospital, Erzincan University, Erzincan, Turkey.
authors.forename: Levent
authors.initials: L
authors.lastname: Demirtaş
authors.affiliation: Department of Cardiology, Rize University, Rize, Turkey.
authors.forename: Hakan
authors.initials: H
authors.lastname: Duman
authors.affiliation: Department of Cardiology, Mengücek Gazi Education and Research Hospital, Erzincan University, Erzincan, Turkey.
authors.forename: Hikmet
authors.initials: H
authors.lastname: Hamur
authors.affiliation: Department of Cardiology, Mengücek Gazi Education and Research Hospital, Erzincan University, Erzincan, Turkey.
authors.forename: Gökhan
authors.initials: G
authors.lastname: Ceyhun
authors.affiliation: Department of Cardiology, Mengücek Gazi Education and Research Hospital, Erzincan University, Erzincan, Turkey.
authors.forename: Ergün
authors.initials: E
authors.lastname: Topal
mesh_terms: D003971:Diastole; D005260:Female; D006325:Heart Atria / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000378:metabolism*; D020097:Natriuretic Peptide, Brain / Q000378:metabolism*
chemical_list: D020097:Natriuretic Peptide, Brain