title: Oxidative photoredox-catalytic activation of aliphatic nucleophiles for C(sp(3))-C(sp(2)) cross-coupling reactions.
abstract: In the light you will find the road (Led Zeppelin): Visible-light photoredox catalysis leads the way in overcoming the reactivity limitations of alkyl nucleophiles in cross-coupling reactions. Iridium-triggered oxidative photoredox activation of alkyltrifluoroborate or carboxylic acids affords alkyl radicals, which undergo nickel-catalyzed cross-coupling reactions.
authors.affiliation: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo náměstí 2, 16610 Prague 6 (Czech Republic) http://www.uochb.cz/web/structure/616.html.
authors.forename: Emanuela
authors.initials: E
authors.lastname: Jahn
authors.forename: Ullrich
authors.initials: U
authors.lastname: Jahn
keywords: amino acids; cross-coupling; nickel; persistent radical effect; photoredox catalysis