title: Histopathological and imaging modifications in chronic ethanolic encephalopathy.
abstract: Chronic abuse of alcohol triggers different types of brain damage. The Wernicke-Korsakoff syndrome gets together Wernicke's encephalopathy and Korsakoff's syndrome. Another type of encephalopathy associated with chronic ethanol consumption is represented by the Marchiafava-Bignami malady or syndrome, an extremely rare neurological disorder, which is characterized by a demielinization of corpus callosum, extending as far as a necrosis. Because the frequency of ethanolic encephalopathy is increased and plays a major role in the sudden death of ethanolic patients, we have studied the chronic ethanolic encephalopathy both in deceased and in living patients, presenting different pathologies related to the chronic ethanol consumption. The present study investigated the effects of chronic ethanolic encephalopathy on the central nervous system based both on the histopathological exam of the tissular samples and the imaging investigation, such as MRI and CT.
authors.affiliation: Department of Anatomy and Embryology, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania; roxanafolescu@yahoo.com.
authors.forename: Roxana
authors.initials: R
authors.lastname: Folescu
authors.forename: Carmen Lăcrămioara
authors.initials: CL
authors.lastname: Zamfir
authors.forename: Alina Maria
authors.initials: AM
authors.lastname: Sişu
authors.forename: Andrei Gheorghe Marius
authors.initials: AG
authors.lastname: Motoc
authors.forename: Adrian Cosmin
authors.initials: AC
authors.lastname: Ilie
authors.forename: Marius
authors.initials: M
authors.lastname: Moise
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology*; D002423:Cause of Death; D015687:Cell Hypoxia; D002908:Chronic Disease; D003952:Diagnostic Imaging; D000431:Ethanol / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009474:Neurons / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D000431:Ethanol