title: Uptake from water, internal distribution and bioaccumulation of selenium in Scenedesmus obliquus, Unio mancus and Rattus norvegicus: part B.
abstract: (75)Se-selenite transfer was investigated in a phytoplankton-mussel-rat food chain model consisting of Scenedesmus obliquus (Turpin) Kützing, Unio mancus Lamark and Rattus norvegicus Berkenhout. (75)Se-metabolized forms were investigated in order to identify potential critical steps in the food chain, as well as its relative bioavailability looking also at intracellular, cellular and organ partitioning. Tissue and intracellular distribution of (75)Se in mussels fed with (75)Se-S. obliquus was different compared to those exposed only to inorganic (75)Se-selenite. The intracellular distribution of (75)Se in the hepatopancreas and mantle of mussels fed (75)Se-microalgae was similar to hepatic and renal distributions in rats, suggesting that their stomach dissociated larger (75)Se-containing molecules. The (75)Se partitioned from water (culture medium) to microalgae showing a bioconcentration factor of 435. The bottleneck in the trophic transfer of (75)Se occurred between S. obliquus-U. mancus. From microalgae to mussels and subsequently to rats no bioaccumulation was verified.
authors.affiliation: CeSI, Aging Research Center, "G. d'Annunzio" University Foundation, Via Colle dell'Ara, 66100, Chieti, Italy.
authors.forename: Enrico
authors.initials: E
authors.lastname: Sabbioni
authors.forename: Aldo-Eliano
authors.initials: AE
authors.lastname: Polettini
authors.forename: Salvador
authors.initials: S
authors.lastname: Fortaner
authors.forename: Massimo
authors.initials: M
authors.lastname: Farina
authors.forename: Flavia
authors.initials: F
authors.lastname: Groppi
authors.forename: Simone
authors.initials: S
authors.lastname: Manenti
authors.forename: Giovanni
authors.initials: G
authors.lastname: Libralato
mesh_terms: D000818:Animals; D001682:Biological Availability; D003470:Culture Media; D020387:Food Chain; D005618:Fresh Water / Q000737:chemistry; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D058086:Microalgae / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D044444:Scenedesmus / Q000378:metabolism*; D012643:Selenium / Q000032:analysis* / Q000493:pharmacokinetics*; D018036:Selenium Compounds / Q000378:metabolism; D013347:Subcellular Fractions; D014018:Tissue Distribution; D049881:Unio / Q000378:metabolism*; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D003470:Culture Media; D018036:Selenium Compounds; D014874:Water Pollutants, Chemical; D012643:Selenium