title: Inhibin alpha-subunit, Melan A and MNF116 in pheochromocytomas.
abstract: OBJECTIVE
  The aim of this study was to make immunohistochemical analyses with Inhibin alpha-subunit, Melan A and MNF116 (pan-Cytokeratin antibody) in pheochromocytomas, because immunohistochemistry is useful for the distinction between adrenal tumors.
  
  
  METHODS
  We used 20 patients with pheochromocytomas submitted to laparoscopic (n=19) or classical (n=1) surgery and we have explored immuno-staining with Inhibin alpha-subunit, Melan A and MNF116 in these tumors. This can be helpful when we cannot make the distinction between adrenal tumors.
  
  
  RESULTS
  Pheochromocytomas did not stain with Inhibin alpha-subunit, Melan A and MNF116.
  
  
  CONCLUSIONS
  In our study, Inhibin alpha-subunit, Melan A and MNF116 were not sensitive for pheochromocytomas.
authors.affiliation: "Prof. Dr. Dorin Hociota" Institute of Phono-Audiology and ENT Functional Surgery, Bucharest, Romania; madalina.georgescu@gecad.com.
authors.forename: Diana
authors.initials: D
authors.lastname: Păun
authors.forename: Marius Cristian
authors.initials: MC
authors.lastname: Neamţu
authors.forename: Elena Taina
authors.initials: ET
authors.lastname: Avramescu
authors.forename: Mădălina Gabriela
authors.initials: MG
authors.lastname: Georgescu
authors.forename: Rodica
authors.initials: R
authors.lastname: Petriş
authors.forename: Dana
authors.initials: D
authors.lastname: Terzea
authors.forename: Cătălina
authors.initials: C
authors.lastname: Poiană
authors.forename: Sorin
authors.initials: S
authors.lastname: Păun
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000378:metabolism*; D005260:Female; D006801:Humans; D007265:Inhibins / Q000378:metabolism*; D007633:Keratins / Q000378:metabolism*; D058965:MART-1 Antigen / Q000378:metabolism*; D008297:Male; D008676:Metanephrine / Q000097:blood; D008875:Middle Aged; D009647:Normetanephrine / Q000097:blood; D010673:Pheochromocytoma / Q000378:metabolism* / Q000473:pathology
chemical_list: D058965:MART-1 Antigen; C526516:cytokeratin MNF116, human; C094377:inhibin-alpha subunit; D009647:Normetanephrine; D008676:Metanephrine; D007265:Inhibins; D007633:Keratins