title: Multicomponent cascade cycloaddition involving tropone, allenoate, and isocyanide: a rapid access to a 7,6,5-fused tricyclic skeleton.
abstract: Multicomponent cascade cycloaddition of tropone, allenoate, and isocyanide has been disclosed. This method allows for the rapid construction of a highly unusual tricyclic skeleton in an efficient manner. The proposed transformation proceeds through [8 + 2 + 1] cycloaddition, [1,5]-H shift, and cyclization followed by an alkoxy group migration process.
authors.affiliation: Department of Chemistry, Innovative Drug Research Center, Shanghai University , 99 Shangda Road, Shanghai 200444, P. R. China.
authors.forename: Shuanglong
authors.initials: S
authors.lastname: Jia
authors.forename: Shikuan
authors.initials: S
authors.lastname: Su
authors.forename: Chunju
authors.initials: C
authors.lastname: Li
authors.forename: Xueshun
authors.initials: X
authors.lastname: Jia
authors.forename: Jian
authors.initials: J
authors.lastname: Li
mesh_terms: D003486:Cyanides / Q000737:chemistry*; D003500:Cyclization; D061565:Cycloaddition Reaction; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry*; D011084:Polycyclic Aromatic Hydrocarbons / Q000737:chemistry*; D013237:Stereoisomerism; D014334:Tropolone / Q000031:analogs & derivatives* / Q000737:chemistry
chemical_list: D003486:Cyanides; D009281:Naphthalenes; D011084:Polycyclic Aromatic Hydrocarbons; D014334:Tropolone; C003730:tropone; C110055:allenolic acid