title: tert-Butyl peroxybenzoate-promoted α-methylation of 1,3-dicarbonyl compounds.
abstract: A tert-butyl peroxybenzoate (TBPB)-promoted direct α-methylation of 1,3-dicarbonyl compounds has been developed, providing α-methyl derivatives in moderate to good yields. In this procedure, TBPB plays a dual role, serving as both the methyl source and radical initiator. This work represents a key complement to the traditional α-methylation of 1,3-dicarbonyl compounds using methyl iodide.
authors.affiliation: School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, Jiangsu Province Key Laboratory of Fine Petrochemical Engineering, Changzhou University , Changzhou 213164, P. R. China.
authors.forename: Songjin
authors.initials: S
authors.lastname: Guo
authors.forename: Qian
authors.initials: Q
authors.lastname: Wang
authors.forename: Yan
authors.initials: Y
authors.lastname: Jiang
authors.forename: Jin-Tao
authors.initials: JT
authors.lastname: Yu
mesh_terms: D001565:Benzoates / Q000737:chemistry*; D006847:Hydrocarbons, Iodinated / Q000138:chemical synthesis* / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D008745:Methylation; D015394:Molecular Structure; D010545:Peroxides / Q000737:chemistry*
chemical_list: D001565:Benzoates; D006847:Hydrocarbons, Iodinated; D007659:Ketones; D010545:Peroxides; C060534:tert-butyl peroxybenzoate; C014055:methyl iodide