title: The role of adult living donor liver transplantation and recent advances.
abstract: Twenty years since the first cases were described, adult living donor liver transplantation (ALDLT) is now considered a valid option to expand the donor pool in view of the ongoing shortage of organs and the high waiting list mortality rate. Despite the rapid evolution and acceptance of this complex process of donation and transplantation in clinical practice, the indications, outcome, ethical considerations and quality and safety aspects continue to evolve based on new data from large cohort studies. This article reviews the surgical and clinical advances in the field of liver transplantation, focusing on technical refinements and discussing the issues that may lead to a further expansion of this complex surgical procedure and the role of ALDLT.
authors.affiliation: Transplant Center, Department of Surgery and Abdominal Transplantation, Niguarda Cà Granda Hospital, Milan, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Lauterio
authors.forename: Stefano
authors.initials: S
authors.lastname: Di Sandro
authors.forename: Alessandro
authors.initials: A
authors.lastname: Giacomoni
authors.forename: Luciano
authors.initials: L
authors.lastname: De Carlis
mesh_terms: D046148:Donor Selection; D058625:End Stage Liver Disease / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects / Q000379:methods* / Q000639:trends; D019520:Living Donors; D061214:Patient Safety; D011183:Postoperative Complications / Q000209:etiology; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome
keywords: HCC; biliary complications; donor mortality; donor outcomes; donor safety; graft size; liver transplantation; living donor; recent advances; robotic liver surgery