title: [New reliable methods for the diagnose of protein-energy wasting in hemodialysis patients].
abstract: BACKGROUND
  Protein-energy wasting (PEW), defined as the body loss of muscle mass and fat, is an important cardiovascular risk factor in dialysis patients. Diagnosing this condition requires the presence of three characteristics: biochemical (low albumine, prealbumine or cholesterol), body mass reduction (body mass index, weight loss or fat loss) and muscle mass reduction (measured by means of creatinine or arm muscle area). This study aimed at demonstrating that the lean tissue index (LTI) calculated by spectroscopic bioimpedance (SBI) is a valid parameter for the diagnostic of protein-energy wasting.
  
  
  METHODS
  Cross-sectional study including 1369 patients with two BCM measurements on a six-month delay, analyzing analytic and spectroscopic bioimpedance parameters.
  
  
  RESULTS
  The lean tissue index from the BCM (Body Composition Monitor) quantifies the patient's lean mass and it is matched against traditional parameters (plasma albumine) and non-traditional parameters (IRE and PCR) for protein-energy wasting with no alterations from the patient's hydration level.
  
  
  CONCLUSIONS
  LTI is an easy to obtain parameter of lean mass which can be followed and monitored in order to diagnose risk situations of our patients as it is the protein- energy wasting.
authors.affiliation: Dirección Médica. Fresenius Medical Care. Madrid. Grupo ORD (Optimizando Resultados de Diálisis).. saandraa101@hotmail.com.
authors.forename: Sandra
authors.initials: S
authors.lastname: Castellano-Gasch
authors.affiliation: Dirección Médica. Fresenius Medical Care. Madrid. Grupo ORD (Optimizando Resultados de Diálisis)..
authors.forename: Inés
authors.initials: I
authors.lastname: Palomares-Sancho
authors.affiliation: Servicio de Nefrología. Hospital Universitario Santa Lucía. Cartagena, Murcia. Grupo ORD (Optimizando Resultados de Diálisis)..
authors.forename: Manuel
authors.initials: M
authors.lastname: Molina-Núñez
authors.affiliation: Dirección Médica. Fresenius Medical Care. Madrid. Grupo ORD (Optimizando Resultados de Diálisis)..
authors.forename: Rosa
authors.initials: R
authors.lastname: Ramos-Sánchez
authors.affiliation: Dirección Médica. Fresenius Medical Care. Madrid. Grupo ORD (Optimizando Resultados de Diálisis)..
authors.forename: José I
authors.initials: JI
authors.lastname: Merello-Godino
authors.affiliation: Servicio de Nefrología. Hospital Clínic de Barcelona. España. Grupo ORD (Optimizando Resultados de Diálisis)..
authors.forename: Francisco
authors.initials: F
authors.lastname: Maduell
mesh_terms: D000368:Aged; D003430:Cross-Sectional Studies; D017097:Electric Impedance; D005260:Female; D006801:Humans; D008297:Male; D011502:Protein-Energy Malnutrition / Q000175:diagnosis*; D006435:Renal Dialysis; D015203:Reproducibility of Results