title: Estimating 24-hour urine sodium level with spot urine sodium and creatinine.
abstract: The 24-hr urine sodium excretion level was estimated based on the spot urine sodium, and the efficacy of the formula was validated to determine the status of low salt intake <100 mEq Na/day. The 24-hr urine samples were collected from 400 patients. The 24-hr urine creatinine level was estimated with the use of three formulas: a newly derived Korean equation (E24UCR_K), and Tanaka (E24UCR_T) and Cockcroft-Gault (E24UCR_CG) equations. The correlation coefficients between the estimated and measured 24-hr urine creatinine for these three equations were 0.863, 0.846, and 0.896, respectively (All P<0.001). After estimating the 24-hr urine sodium levels, the correlation coefficients between the estimated and measured 24-hr urine sodium levels were 0.466, 0.490, and 0.516, respectively (All P<0.001). The sensitivity of three formulas to estimate the measured 24-hr urine sodium≥100 mEq/day using the estimated amount≥100 mEq/day was 84.3%, 87.6%, and 84.8%, respectively. In conclusion, the three equations used to estimate the 24-hr urine sodium content were useful to determine the status of low salt intake.
authors.affiliation: Department of Internal Medicine, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea.
authors.forename: Ho Seok
authors.identifier: 0000-0001-7856-8083
authors.initials: HS
authors.lastname: Koo
authors.affiliation: Department of Internal Medicine, Armed Forces Capital Hospital, Seongnam, Korea.
authors.forename: Yong Chul
authors.initials: YC
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Shin Young
authors.initials: SY
authors.lastname: Ahn
authors.affiliation: Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
authors.forename: Se Won
authors.initials: SW
authors.lastname: Oh
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. ; The Research Institute of Salt and Health, Seoul, Korea. ; Seoul K-Clinic, Seoul, Korea.
authors.forename: Suhnggwon
authors.initials: S
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. ; The Research Institute of Salt and Health, Seoul, Korea. ; Department of Immunology, Seoul National University Postgraduate School, Seoul, Korea. ; Renal Institute, Seoul National University Medical Research Center, Seoul, Korea.
authors.forename: Ho Jun
authors.identifier: 0000-0003-1185-2631
authors.initials: HJ
authors.lastname: Chin
authors.affiliation: Department of Internal Medicine, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Jung Hwan
authors.identifier: 0000-0002-8737-0084
authors.initials: JH
authors.lastname: Park
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D019540:Area Under Curve; D003404:Creatinine / Q000652:urine*; D003710:Demography; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D012372:ROC Curve; D012982:Sodium, Dietary / Q000652:urine*; D059349:Urine Specimen Collection
chemical_list: D012982:Sodium, Dietary; D003404:Creatinine
keywords: 24-hr Urine Sodium; Spot Urine Creatinine; Spot Urine Sodium