title: An overview of optical coherence tomography for ovarian tissue imaging and characterization.
abstract: Ovarian cancer has the lowest survival rate among all the gynecologic cancers because it is predominantly diagnosed at late stages due to the lack of reliable symptoms and efficacious screening techniques. Optical coherence tomography (OCT) is an emerging technique that provides high-resolution images of biological tissue in real time, and demonstrates great potential for imaging of ovarian tissue. In this article, we review OCT studies for visualization and diagnosis of human ovaries as well as quantitative extraction of ovarian tissue optical properties for classifying normal and malignant ovaries. OCT combined with other imaging modalities to further improve ovarian tissue diagnosis is also reviewed.
authors.affiliation: Department of Electrical and Computer Engineering, University of Connecticut, Storrs, CT, USA.
authors.forename: Tianheng
authors.initials: T
authors.lastname: Wang
authors.forename: Molly
authors.initials: M
authors.lastname: Brewer
authors.forename: Quing
authors.initials: Q
authors.lastname: Zhu
mesh_terms: D000162:Acoustics; D003287:Contrast Media / Q000737:chemistry; D003952:Diagnostic Imaging / Q000379:methods; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008853:Microscopy / Q000379:methods; D064847:Multimodal Imaging / Q000379:methods; D010051:Ovarian Neoplasms / Q000473:pathology*; D010053:Ovary / Q000473:pathology*; D049268:Positron-Emission Tomography / Q000379:methods; D041623:Tomography, Optical Coherence / Q000379:methods*
chemical_list: D003287:Contrast Media