title: Shining light on the dark side of imaging: excited state absorption enhancement of a bis-styryl BODIPY photoacoustic contrast agent.
abstract: A first approach toward understanding the targeted design of molecular photoacoustic contrast agents (MPACs) is presented. Optical and photoacoustic Z-scan spectroscopy was used to identify how nonlinear (excited-state) absorption contributes to enhancing the photoacoustic emission of the curcuminBF2 and bis-styryl (MeOPh)2BODIPY dyes relative to Cy3.
authors.affiliation: Department of Chemistry and ‡Department of Physics, University of Massachusetts Boston , 100 Morrissey Boulevard, Boston, Massachusetts 02125, United States.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Frenette
authors.forename: Maryam
authors.initials: M
authors.lastname: Hatamimoslehabadi
authors.forename: Stephanie
authors.initials: S
authors.lastname: Bellinger-Buckley
authors.forename: Samir
authors.initials: S
authors.lastname: Laoui
authors.forename: Jeffrey
authors.initials: J
authors.lastname: La
authors.forename: Seema
authors.initials: S
authors.lastname: Bag
authors.forename: Srivalleesha
authors.initials: S
authors.lastname: Mallidi
authors.forename: Tayyaba
authors.initials: T
authors.lastname: Hasan
authors.forename: Brett
authors.initials: B
authors.lastname: Bouma
authors.forename: Chandra
authors.initials: C
authors.lastname: Yelleswarapu
authors.forename: Jonathan
authors.initials: J
authors.lastname: Rochford
mesh_terms: D065966:Absorption, Physicochemical; D001896:Boron Compounds / Q000737:chemistry*; D004396:Coloring Agents / Q000737:chemistry; D003287:Contrast Media / Q000737:chemistry*; D015195:Drug Design; D061848:Optical Imaging / Q000379:methods*; D061088:Photoacoustic Techniques / Q000379:methods*
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D004396:Coloring Agents; D003287:Contrast Media