title: [Use of the intravenous and nebulized magnesium sulfate for the treatment of the acute asthma in the emergence].
abstract: OBJECTIVE
  Magnesium sulfate has been shown to benefit asthmatic children and adults with poor responses to initial beta-agonist therapy and systemic corticoids in the emergency department. The aim of this study was to realize a no systematic review about the treatment of the acute asthma with intravenous and nebulized magnesium sulfate in the emergence.
  
  
  BACKGROUND
  The first investigations that demonstrate the benefit in the use of the magnesium sulfate in asthma date to 1938. The effects of magnesium sulfate may be mediated through its action as a calcium antagonist or through its function as a cofactor in enzyme systems involving ion flux across cell membranes. We realized a literature review using MedLine database of the last six years (2000 to 2006). Articles published in English were included by the crossing of keywords asthma and magnesium sulfate.
  
  
  CONCLUSIONS
  The routine administration of intravenous and nebulized magnesium sulfate to severely ill patients with acute asthma presents in the emergence department is not recommended, however as an adjunct therapy brings some benefit.
authors.affiliation: Clínica Santa Juliana.
authors.forename: Fabiano Timbó
authors.initials: FT
authors.lastname: Barbosa
authors.affiliation: Hospital da Agroindústria do Açúcar e do Álcool do Estado de Alagoas.
authors.forename: Luciano Timbó
authors.initials: LT
authors.lastname: Barbosa
authors.affiliation: Hospital Unimed, Maceió
authors.forename: Rafael Martins da
authors.initials: RM
authors.lastname: Cunha
authors.affiliation: Universidade de Ciências da Saúde de Alagoas.
authors.forename: Giulliano Peixoto
authors.initials: GP
authors.lastname: Gonçalves
authors.affiliation: Universidade de Ciências da Saúde de Alagoas.
authors.forename: Diego Agra de
authors.initials: DA
authors.lastname: Souza