title: Hyaluronic acid-polypyrrole nanoparticles as pH-responsive theranostics.
abstract: Doxorubicin-loaded hyaluronic acid-polypyrrole nanoparticles were developed for pH-responsive activatable fluorescence imaging and therapy of proliferating macrophages.
authors.affiliation: Molecular Imaging & Therapy Branch, National Cancer Center, 323 Ilsan-ro, Goyang-si, Gyeonggi-do 410-769, Korea. ydchoi@ncc.re.kr.
authors.forename: Dongjin
authors.initials: D
authors.lastname: Park
authors.forename: Youngnam
authors.initials: Y
authors.lastname: Cho
authors.forename: Sung-Ho
authors.initials: SH
authors.lastname: Goh
authors.forename: Yongdoo
authors.initials: Y
authors.lastname: Choi
mesh_terms: D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000737:chemistry / Q000627:therapeutic use; D050197:Atherosclerosis / Q000175:diagnosis / Q000188:drug therapy / Q000378:metabolism; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D004317:Doxorubicin / Q000737:chemistry / Q000627:therapeutic use; D006801:Humans; D006820:Hyaluronic Acid / Q000737:chemistry / Q000627:therapeutic use; D006863:Hydrogen-Ion Concentration; D008264:Macrophages / Q000187:drug effects; D051379:Mice; D032389:Myocytes, Smooth Muscle / Q000187:drug effects; D053758:Nanoparticles / Q000737:chemistry / Q000627:therapeutic use; D061848:Optical Imaging; D011108:Polymers / Q000737:chemistry / Q000627:therapeutic use; D011758:Pyrroles / Q000737:chemistry / Q000627:therapeutic use
chemical_list: D000903:Antibiotics, Antineoplastic; D011108:Polymers; D011758:Pyrroles; C067635:polypyrrole; D004317:Doxorubicin; D006820:Hyaluronic Acid