title: Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret.
abstract: A 5-year-old male ferret presented with an enlarged canalicular testis in the left inguinal region. Microscopically, the enlarged testis consisted of a diffuse intimately admixed proliferation of c-kit-positive germ cell-like and Wilms tumor-1 protein-positive Sertoli cell-like components, but no Call-Exner body was detected. In addition, the compact proliferation of steroidogenic acute regulatory protein-intense positive interstitial cells was identified in a separate peripheral area of the mass. Based on histopathological and immunohistochemical findings, the tumor was diagnosed as a mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor.
authors.affiliation: Laboratory of Veterinary Pathology, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan.
authors.forename: Saki
authors.initials: S
authors.lastname: Inoue
authors.forename: Kayoko
authors.initials: K
authors.lastname: Yonemaru
authors.forename: Tokuma
authors.initials: T
authors.lastname: Yanai
authors.forename: Hiroki
authors.initials: H
authors.lastname: Sakai
mesh_terms: D000818:Animals; D005289:Ferrets; D007984:Leydig Cell Tumor / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D008297:Male; D018312:Sex Cord-Gonadal Stromal Tumors / Q000473:pathology / Q000601:surgery / Q000662:veterinary*