title: Shared decision making for hydroxyurea treatment initiation in children with sickle cell anemia.
abstract: Clinical trials have demonstrated hydroxyurea's efficacy in improving health outcomes for children with sickle cell anemia (SCA) who have medical complications. New NHLBI clinical guidelines will recommend offering hydroxyurea to young patients regardless of clinical severity. Shared decision making may be an effective approach for implementing this practice change. Decision aids that help patients/parents feel empowered to make this decision and help providers feel comfortable in discussing hydroxyurea as a preventive treatment may facilitate shared discussions between families and providers. We recommend six strategies providers can use to facilitate these discussions while decision aids and tools are being developed. Pediatr Blood Cancer 2015;62:184-185. © 2014 Wiley Periodicals, Inc.
authors.affiliation: Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.|Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
authors.forename: Lori E
authors.initials: LE
authors.lastname: Crosby
authors.affiliation: Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.|Cancer and Blood Diseases Institute, Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
authors.forename: Lisa M
authors.initials: LM
authors.lastname: Shook
authors.affiliation: Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.|Cancer and Blood Diseases Institute, Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.|Center for Global Health, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
authors.forename: Russell E
authors.initials: RE
authors.lastname: Ware
authors.affiliation: Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.|Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.|James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
authors.forename: William B
authors.initials: WB
authors.lastname: Brinkman
mesh_terms: D000755:Anemia, Sickle Cell / Q000188:drug therapy*; D000986:Antisickling Agents / Q000627:therapeutic use*; D002648:Child; D000066491:Clinical Decision-Making; D003657:Decision Making; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use*; D010290:Parents; D010817:Physician-Patient Relations
chemical_list: D000986:Antisickling Agents; D006918:Hydroxyurea
keywords: decision‐making; guidelines; pediatrics; sickle cell anemia; therapeutics