title: A practical application of text mining to literature on cognitive rehabilitation and enhancement through neurostimulation.
abstract: The exponential growth in publications represents a major challenge for researchers. Many scientific domains, including neuroscience, are not yet fully engaged in exploiting large bodies of publications. In this paper, we promote the idea to partially automate the processing of scientific documents, specifically using text mining (TM), to efficiently review big corpora of publications. The "cognitive advantage" given by TM is mainly related to the automatic extraction of relevant trends from corpora of literature, otherwise impossible to analyze in short periods of time. Specifically, the benefits of TM are increased speed, quality and reproducibility of text processing, boosted by rapid updates of the results. First, we selected a set of TM-tools that allow user-friendly approaches of the scientific literature, and which could serve as a guide for researchers willing to incorporate TM in their work. Second, we used these TM-tools to obtain basic insights into the relevant literature on cognitive rehabilitation (CR) and cognitive enhancement (CE) using transcranial magnetic stimulation (TMS). TM readily extracted the diversity of TMS applications in CR and CE from vast corpora of publications, automatically retrieving trends already described in published reviews. TMS emerged as one of the important non-invasive tools that can both improve cognitive and motor functions in numerous neurological diseases and induce modulations/enhancements of many fundamental brain functions. TM also revealed trends in big corpora of publications by extracting occurrence frequency and relationships of particular subtopics. Moreover, we showed that CR and CE share research topics, both aiming to increase the brain's capacity to process information, thus supporting their integration in a larger perspective. Methodologically, despite limitations of a simple user-friendly approach, TM served well the reviewing process.
authors.affiliation: Laboratory for Neuro-and Psychophysiology, Katholieke Universiteit Leuven Medical School Leuven, Belgium.
authors.forename: Puiu F
authors.initials: PF
authors.lastname: Balan
authors.affiliation: Laboratory for Neuro-and Psychophysiology, Katholieke Universiteit Leuven Medical School Leuven, Belgium.
authors.forename: Annelies
authors.initials: A
authors.lastname: Gerits
authors.affiliation: Laboratory for Neuro-and Psychophysiology, Katholieke Universiteit Leuven Medical School Leuven, Belgium ; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital Charlestown, MA, USA ; Department of Radiology, Harvard Medical School Charlestown, MA, USA.
authors.forename: Wim
authors.initials: W
authors.lastname: Vanduffel
keywords: cognitive; enhancement; rehabilitation; text mining; transcranial magnetic stimulation