title: [Drugs: an underestimated cause of arterial hypertension].
abstract: In Switzerland, as in other Occidental countries, the prevalence of arterial hypertension (AHT) in the adult population is around 30-40%. Among the causes of secondary AHT, drug induced hypertension is sometimes omitted. Many molecules can induce AHT or worsen it due to an interaction with anti hypertensive drugs. Among these, NSAIDs and anti depressants, widely prescribed, should be used with caution, particularly in patients at risk, namely: those with preexisting AHT, the elderly, or patients suffering from kidney disease, diabetes, and/or heart failure. Increases in blood pressure have also been described with anti-vascular endothelial growth factor (VEGF) drugs, used in the treatment of (metastatic) cancer. A thorough anamnesis of drugs, including over the counter ones, should be performed in every hypertensive patient, and can avoid cumbersome and unnecessary investigations and therapy.
authors.forename: Marianne
authors.initials: M
authors.lastname: Serveaux
authors.forename: Michel
authors.initials: M
authors.lastname: Burnier
authors.forename: Menno
authors.initials: M
authors.lastname: Pruijm
mesh_terms: D000328:Adult; D020533:Angiogenesis Inhibitors / Q000009:adverse effects; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D000928:Antidepressive Agents / Q000009:adverse effects; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D006973:Hypertension / Q000139:chemically induced* / Q000453:epidemiology*; D014663:Nasal Decongestants / Q000009:adverse effects; D013557:Switzerland / Q000453:epidemiology; D042461:Vascular Endothelial Growth Factor A / Q000037:antagonists & inhibitors
chemical_list: D020533:Angiogenesis Inhibitors; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000928:Antidepressive Agents; D014663:Nasal Decongestants; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A