title: [Perspective research of the influence of caloric restriction combined with psychotherapy and chemotherapy associated by hybaroxia on the prognosis of patients suffered by glioblastoma multiforme].
abstract: OBJECTIVE
  To explore the influence of caloric restriction combined with psychotherapy and chemotherapy associated by hybaroxia on the prognosis of patients with intracranial glioblastoma multiforme.
  
  
  METHODS
  This was a perspective, nonrandom, no-double-blinded controlled study. All patients underwent total resection during November 2007 to April 2009 at Beijing Tiantan Hospital and Beijing Tiantan Puhua Hospital. All diagnoses were confirmed by molecule pathology. While 23 patients in control group underwent resections and radiochemotherapy, 11 patients in experimental group were further treated by caloric restriction plus psychotherapy and chemotherapy-associated hybaroxia. The life spans were compared between two groups.
  
  
  RESULTS
  The mean survival time of patients in experimental group was (38 ± 13) months versus (20 ± 12) months in control group. The survival time of patients in experimental group was significantly longer than that in control group (P < 0.05).
  
  
  CONCLUSIONS
  Caloric restriction plus psychotherapy and chemotherapy-associated hybaroxia can apparently prolong the life span of patients with glioblastoma multiforme.
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
authors.forename: Lijiang
authors.initials: L
authors.lastname: Han
authors.forename: Junting
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Email: hanljjlna@126.com.
authors.forename: Pengfei
authors.initials: P
authors.lastname: Zhang
authors.forename: Xiaodi
authors.initials: X
authors.lastname: Han
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Bi
authors.forename: Jian
authors.initials: J
authors.lastname: Li
authors.forename: Liang
authors.initials: L
authors.lastname: Wang
authors.forename: Fengwen
authors.initials: F
authors.lastname: Xue
authors.forename: Yanzhu
authors.initials: Y
authors.lastname: Fan
mesh_terms: D001932:Brain Neoplasms / Q000150:complications*; D031204:Caloric Restriction; D003131:Combined Modality Therapy; D005909:Glioblastoma / Q000150:complications*; D006801:Humans; D010101:Oxygen Consumption; D011379:Prognosis; D011613:Psychotherapy; D015996:Survival Rate