title: [Placental 3D Doppler angiography: current and upcoming applications].
abstract: The placental dysfunction, which seems to be caused by a defect of trophoblastic invasion and impaired uterine vascular remodeling since the first trimester, is responsible in a non-exclusive way for the chronic placental hypoxia, resulting secondarily in the intra-uterine growth restriction (IUGR) and/or pre-eclampsia (PE). The quality of utero-placental vasculature is essential for a proper fetal development and a successful progress of pregnancy. However, the in vivo assessment of placental vascularization with non-invasive methods is complicated by the small size of placental terminal vessel and its complex architecture. Moreover, imaging with contrast agent is not recommended to pregnant women. Until recently, the fetal and maternal vascularization could only be evaluated through pulse Doppler of uterine arteries during pregnancy, which has little clinical value for utero-placental vascularization defects assessment. Recently, a non-invasive study, without use of contrast agent for vasculature evaluation of an organ of interest has become possible by the development of 3D Doppler angiography technique. The objective of this review was to make an inventory of its current and future applications for utero-placental vasculature quantification. The main findings of the literature on the assessment of utero-placental vascularization in physiological situation and major placental vascular dysfunction pathologies such as PE and IUGR were widely discussed.
authors.affiliation: IADI, université de Lorraine, rue du Morvan, 54511 Vandœuvre-Lès-Nancy, France; Inserm U947, rue du Morvan, 54511 Vandœuvre-Lès-Nancy, France. Electronic address: jieduan131@gmail.com.
authors.forename: J
authors.initials: J
authors.lastname: Duan
authors.affiliation: IADI, université de Lorraine, rue du Morvan, 54511 Vandœuvre-Lès-Nancy, France; Inserm U947, rue du Morvan, 54511 Vandœuvre-Lès-Nancy, France; Pôle de la femme, service d'obstétrique et médecine fœtale, centre hospitalier universitaire de Nancy, 10, rue Heydenreich, 54000 Nancy, France.
authors.forename: E
authors.initials: E
authors.lastname: Perdriolle-Galet
authors.affiliation: IADI, université de Lorraine, rue du Morvan, 54511 Vandœuvre-Lès-Nancy, France; Pôle de la femme, service d'obstétrique et médecine fœtale, centre hospitalier universitaire de Nancy, 10, rue Heydenreich, 54000 Nancy, France.
authors.forename: A-C
authors.initials: AC
authors.lastname: Chabot-Lecoanet
authors.affiliation: Pôle de la femme, service d'obstétrique et médecine fœtale, centre hospitalier universitaire de Nancy, 10, rue Heydenreich, 54000 Nancy, France.
authors.forename: R
authors.initials: R
authors.lastname: Callec
authors.affiliation: CIC-IT, Inserm CIC-IT 1433, université de Lorraine, rue du Morvan, 54511 Vandœuvre-Lès-Nancy, France.
authors.forename: M
authors.initials: M
authors.lastname: Beaumont
authors.affiliation: Inra, UMR 1198, biologie du développement et reproduction, 78350 Jouy-en-Josas, France; ENVA, avenue du Général-de-Gaulle, 94704 Maisons-Alfort, France; Fondation PremUp, 4, avenue de l'Observatoire, 75006 Paris, France.
authors.forename: P
authors.initials: P
authors.lastname: Chavatte-Palmer
authors.affiliation: Fondation PremUp, 4, avenue de l'Observatoire, 75006 Paris, France; Service d'obstétrique et gynécologique, maternité Port-Royal, université Paris Descartes, AP-HP, 53, avenue de l'Observatoire, 75006 Paris, France.
authors.forename: V
authors.initials: V
authors.lastname: Tsatsaris
authors.affiliation: IADI, université de Lorraine, rue du Morvan, 54511 Vandœuvre-Lès-Nancy, France; Inserm U947, rue du Morvan, 54511 Vandœuvre-Lès-Nancy, France; Pôle de la femme, service d'obstétrique et médecine fœtale, centre hospitalier universitaire de Nancy, 10, rue Heydenreich, 54000 Nancy, France.
authors.forename: O
authors.initials: O
authors.lastname: Morel
mesh_terms: D000792:Angiography / Q000379:methods*; D005260:Female; D005317:Fetal Growth Retardation / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D021621:Imaging, Three-Dimensional; D010920:Placenta / Q000098:blood supply* / Q000000981:diagnostic imaging*; D011225:Pre-Eclampsia / Q000000981:diagnostic imaging / Q000503:physiopathology; D011247:Pregnancy; D018615:Ultrasonography, Doppler, Color; D016216:Ultrasonography, Prenatal / Q000379:methods; D055988:Uterine Artery / Q000000981:diagnostic imaging / Q000503:physiopathology; D014599:Uterus / Q000098:blood supply / Q000000981:diagnostic imaging
keywords: 3D power Doppler; Angiographie; Angiography; Doppler énergie 3D; Indices vasculaires; Utero-placental vascularization; Vascular indices; Vascularisation utéroplacentaire