title: Silver-promoted oxidative cyclization of 1,6-enynes: highly regioselective synthesis of phosphorated fluorene derivatives.
abstract: A silver-promoted oxidative cyclization of 1,6-enynes with disubstituted phosphine oxides is developed for the synthesis of fluorene derivatives. The reaction proceeds with high regioselectivity by constructing one C-P bond and two C-C bonds in one step. Moreover, reduction of the pentavalent phosphine enlarges the application scope of the product.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou 730000, P.R. China.
authors.forename: Zhao-Zhao
authors.initials: ZZ
authors.lastname: Zhou
authors.forename: Dong-Po
authors.initials: DP
authors.lastname: Jin
authors.forename: Lian-Hua
authors.initials: LH
authors.lastname: Li
authors.forename: Yu-Tao
authors.initials: YT
authors.lastname: He
authors.forename: Ping-Xin
authors.initials: PX
authors.lastname: Zhou
authors.forename: Xiao-Biao
authors.initials: XB
authors.lastname: Yan
authors.forename: Xue-Yuan
authors.initials: XY
authors.lastname: Liu
authors.forename: Yong-Min
authors.initials: YM
authors.lastname: Liang
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D005449:Fluorenes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010720:Phosphines / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D005449:Fluorenes; D010720:Phosphines; D012834:Silver; C041509:fluorene