title: Prevalence and histopathological types of skin carcinomas in Arges County, Romania.
abstract: Non-melanoma skin cancers presented a significant incidence increase in the last decades, worldwidely. Even though the impact upon mortality is a relatively low one, through the incidence increase, their impact upon the public healthcare systems is a considerable one. In our study, we evaluated 109 cases of skin carcinomas hospitalized during 2012 in the Department of Plastic Surgery of the Emergency Hospital of Pitesti, Romania, for a surgical treatment. The gender distribution showed slight lesion predominance in women, being recorded 56 (51.38%) tumors in women and 53 (48.62%) in men. The highest incidence of skin carcinomas (75.23%) was recorded in the persons aged over 60-year-old. Of 109 cases of skin carcinomas, 80 (73.4%) carcinomas developed on indignant tegument areas, while 29 (26.6%) on premalignant skin lesions (fiberconjunctive papillomas, keratocantomas, keratosic verrucas). The histopathological study highlighted the fact that of 109 skin carcinomas, 87 (79.82%) were basal cell carcinomas and only 22 (20.18%) were squamous cell carcinomas. The immunohistochemical reaction to 34βE12 cytokeratin was highly positive in the cells of the basal cell carcinomas and well-differentiated squamous cell carcinomas (except for the "keratosic pearls") and moderately positive in the moderately differentiated squamous cell carcinoma.
authors.affiliation: Department of Histology, University of Medicine and Pharmacy of Craiova, Romania; andrei_theo@yahoo.com.
authors.forename: Marilena Monica
authors.initials: MM
authors.lastname: Tânţu
authors.forename: Eduard
authors.initials: E
authors.lastname: Belu
authors.forename: George Mihail
authors.initials: GM
authors.lastname: Man
authors.forename: Dan
authors.initials: D
authors.lastname: Manu
authors.forename: Liliana Marcela
authors.initials: LM
authors.lastname: Rogozea
authors.forename: Cristina Mariana
authors.initials: CM
authors.lastname: Stocheci
authors.forename: Andrei Theodor
authors.initials: AT
authors.lastname: Bălăşoiu
authors.forename: Casiana
authors.initials: C
authors.lastname: Stănescu
authors.forename: Carmen Daniela
authors.initials: CD
authors.lastname: Domnariu
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002280:Basal Cell Carcinoma / Q000453:epidemiology / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000473:pathology; D002454:Cell Differentiation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012383:Romania / Q000453:epidemiology; D012878:Skin Neoplasms / Q000453:epidemiology* / Q000473:pathology*; D055815:Young Adult