title: Comparison of postprandial lipemia between women who are on oral contraceptive methods and those who are not.
abstract: BACKGROUND
  Postprandial Lipemia (PPL) is a physiological process that reflects the ability of the body to metabolize lipids. Even though the influence of oral contraceptives (OC) on PPL is not known, it is a known fact that their use increases fasting lipid values.
  
  
  OBJECTIVE
  To compare the PPL between women who are on OC and those who are not.
  
  
  METHODS
  A prospective analytical study which assessed eutrophic women, aged between 18 and 28 years old, who were irregularly active and with fasting triglycerides ≤ 150 mg/dL. They were divided into two groups: oral contraceptive group (COG) and non-oral contraceptive group (NCOG). Volunteers were submitted to the PPL test, in which blood samples were collected in time 0 (12-hour fasting) and after the intake of lipids in times 180 and 240 minutes. In order to compare the triglyceride deltas, which reflect PPL, the two-tailed Mann-Whitney test was used for independent samples between fasting collections and 180 minutes (Δ1) and between fasting and 240 minutes (Δ2).
  
  
  RESULTS
  Forty women were assessed and equally divided between groups. In the fasting lipid profile, it was observed that HDL did not present significant differences and that triglycerides in COG were twice as high in comparison to NCOG. Medians of Δ1 and Δ2 presented significant differences in both comparisons (p ≤ 0.05).
  
  
  CONCLUSIONS
  The results point out that women who are irregularly active and use OC present more PPL in relation to those who do not use OC, which suggests that in this population, its chronic use increases the risk of heart conditions.
authors.affiliation: Escola Bahiana de Medicina e Saúde Pública, Salvador, BA, Brazil.
authors.forename: Jefferson
authors.initials: J
authors.lastname: Petto
authors.affiliation: Grupo de Pesquisa em Cardiologia, Faculdade Social da Bahia, Salvador, BA, Brazil.
authors.forename: Leila Monique Reis
authors.initials: LM
authors.lastname: Vasques
authors.affiliation: Grupo de Pesquisa em Cardiologia, Faculdade Social da Bahia, Salvador, BA, Brazil.
authors.forename: Renata Leão
authors.initials: RL
authors.lastname: Pinheiro
authors.affiliation: Grupo de Pesquisa em Cardiologia, Faculdade Social da Bahia, Salvador, BA, Brazil.
authors.forename: Beatriz de Almeida
authors.initials: Bde A
authors.lastname: Giesta
authors.affiliation: Grupo de Pesquisa em Cardiologia, Faculdade Social da Bahia, Salvador, BA, Brazil.
authors.forename: Alan Carlos Nery dos
authors.initials: AC
authors.lastname: Santos
authors.affiliation: Grupo de Pesquisa em Cardiologia, Faculdade Social da Bahia, Salvador, BA, Brazil.
authors.forename: Mansueto
authors.initials: M
authors.lastname: Gomes Neto
authors.affiliation: Escola Bahiana de Medicina e Saúde Pública, Salvador, BA, Brazil.
authors.forename: Ana Marice Teixeira
authors.initials: AM
authors.lastname: Ladeia
mesh_terms: D000328:Adult; D000367:Age Factors; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000209:etiology / Q000378:metabolism; D008076:Cholesterol, HDL / Q000097:blood; D003276:Contraceptives, Oral / Q000008:administration & dosage*; D005215:Fasting / Q000097:blood; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood*; D008055:Lipids / Q000097:blood*; D019518:Postprandial Period / Q000502:physiology*; D012016:Reference Values; D012307:Risk Factors; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires; D013997:Time Factors; D014280:Triglycerides / Q000097:blood; D055815:Young Adult
chemical_list: D008076:Cholesterol, HDL; D003276:Contraceptives, Oral; D008055:Lipids; D014280:Triglycerides