title: Simple synthetic receptors for aspirin.
abstract: Shallow methylene-bridged cavitands appended with simple H-bond donor/acceptor groups are shown to bind aspirin. The structural features needed in a synthetic receptor for aspirin binding are defined.
authors.affiliation: Research School of Chemistry, Building 137, The Australian National University, Canberra, ACT 2601 (Australia), Fax: (+61) 2 6125 8114.
authors.forename: Thanh V
authors.initials: TV
authors.lastname: Nguyen
authors.forename: Michael S
authors.initials: MS
authors.lastname: Sherburn
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry*; D001241:Aspirin / Q000737:chemistry*; D001665:Binding Sites; D004988:Ethers, Cyclic / Q000737:chemistry; D006860:Hydrogen Bonding; D008958:Models, Molecular; D062165:Receptors, Artificial / Q000737:chemistry*; D012118:Resorcinols / Q000737:chemistry
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D004988:Ethers, Cyclic; D062165:Receptors, Artificial; D012118:Resorcinols; C442939:cavitand; D001241:Aspirin
keywords: aspirin; cavitands; host-guest systems; selective binding; synthetic receptors