title: The prognosis of patients less than 40 years with bladder cancer.
abstract: OBJECTIVE
  Natural history of young patients with bladder cancer has not yet been known. So this study aimed to understand characteristics and prognosis of patients less than 40 years with bladder cancer.
  
  
  METHODS
  We retrospectively analyzed 42 patients (group 1) less than 40 years with bladder cancer followed up for 6 months at least from October 1998 to January 2010. As controlled group (group 2) consisted 44 patients of 60 years or more who had same condition as above mentioned from January to December 2009 was set. Tumor size and number, pathological results, urine cytology results and recurrence rate were reviewed.
  
  
  RESULTS
  The mean ages and the gender distribution in the two groups showed no difference. Tumor size (P = 0.021) and number (P = 0.016) in group 1 was smaller than control. The proportion of muscle invasive type was not significant, but pTa in group 1 was occupied larger portion than group 2 (P = 0.01). Group 1 had more low grade cancer (P = 0.013), and lower recurrence rate (7.1%) than group 2 (38.6%) (P = 0.001). In addition, the mean recurrence free duration of group 1 and 2 were 37.7 ± 6.3 and 9.9 ± 2.5 months, respectively. Group 1 showed later relapse than group 2 (P = 0.002). No progression in stage at recurrence was in group 1, but 1 case had progression in group 2. In grade, 1 case was worsen in group 1 and 3 cases were worsen in group 2.
authors.forename: Seong Woong
authors.initials: SW
authors.lastname: Na
authors.forename: Seong Hyeon
authors.initials: SH
authors.lastname: Yu
authors.forename: Kwang Ho
authors.initials: KH
authors.lastname: Kim
authors.forename: Eu Chang
authors.initials: EC
authors.lastname: Hwang
authors.forename: Seung Il
authors.initials: SI
authors.lastname: Jung
authors.forename: Dong Deuk
authors.initials: DD
authors.lastname: Kwon
authors.affiliation: Department of Urology, Research Institute of Medical Sciences, Chonnam National University Medical School, Gwangju, Korea.
authors.forename: Taek Won
authors.initials: TW
authors.lastname: Kang
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D060787:Neoplasm Grading; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D047368:Tumor Burden; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000473:pathology; D055815:Young Adult