title: Consensus statement on the immunohistochemical detection of ocular lymphatic vessels.
abstract: There is currently considerable controversy about existence and classification of "lymphatic vessels" in the eye. Some of the confusion is certainly caused by inappropriate use (or nonuse) of the correct immunohistochemical markers. Many experts in the field expressed the need for a consensus statement, and, in this perspective, authors offer arguments and solutions to reliably continue with immunohistochemical ocular lymphatic research.
authors.affiliation: Department of Ophthalmology and Optometry, Paracelsus Medical University, Salzburg, Austria Department of Anatomy, Paracelsus Medical University, Salzburg, Austria.
authors.forename: Falk
authors.initials: F
authors.lastname: Schroedl
authors.affiliation: Department of Ophthalmology and Optometry, Paracelsus Medical University, Salzburg, Austria.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Kaser-Eichberger
authors.affiliation: Department of Ophthalmology, University of Cologne, Cologne, Germany.
authors.forename: Simona L
authors.initials: SL
authors.lastname: Schlereth
authors.affiliation: Department of Ophthalmology, University of Cologne, Cologne, Germany.
authors.forename: Felix
authors.initials: F
authors.lastname: Bock
authors.affiliation: Department of Ophthalmology, University of Cologne, Cologne, Germany.
authors.forename: Birgit
authors.initials: B
authors.lastname: Regenfuss
authors.affiliation: Department of Ophthalmology and Optometry, Paracelsus Medical University, Salzburg, Austria.
authors.forename: Herbert A
authors.initials: HA
authors.lastname: Reitsamer
authors.affiliation: Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, Maryland, United States.
authors.forename: Gerard A
authors.initials: GA
authors.lastname: Lutty
authors.affiliation: Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
authors.forename: Kazuichi
authors.initials: K
authors.lastname: Maruyama
authors.affiliation: Center for Eye Disease & Development, Program in Vision Science and School of Optometry, University of California at Berkeley, Berkeley, California, United States.
authors.forename: Lu
authors.initials: L
authors.lastname: Chen
authors.affiliation: Department of Anatomy II, University Erlangen-Nuremberg, Erlangen, Germany.
authors.forename: Elke
authors.initials: E
authors.lastname: Lütjen-Drecoll
authors.affiliation: Massachusetts Eye and Ear Infirmary and Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts, United States.
authors.forename: Reza
authors.initials: R
authors.lastname: Dana
authors.affiliation: Department of Pathology, Medical University Vienna, Vienna, Austria.
authors.forename: Dontscho
authors.initials: D
authors.lastname: Kerjaschki
authors.affiliation: Institute of Biomedicine, University of Helsinki, Helsinki, Finland.
authors.forename: Kari
authors.initials: K
authors.lastname: Alitalo
authors.affiliation: Istituto Pasteur-Fondazione Cenci Bolognetti, Department of Biology and Biotechnology "Charles Darwin," Sapienza University of Rome, Roma, Italy.
authors.forename: Maria Egle
authors.initials: ME
authors.lastname: De Stefano
authors.affiliation: School of Optometry and Vision Science, University of New South Wales, Sydney, Australia.
authors.forename: Barbara M
authors.initials: BM
authors.lastname: Junghans
authors.affiliation: Department of Ophthalmology, University of Cologne, Cologne, Germany.
authors.forename: Ludwig M
authors.initials: LM
authors.lastname: Heindl
authors.affiliation: Department of Ophthalmology, University of Cologne, Cologne, Germany.
authors.forename: Claus
authors.initials: C
authors.lastname: Cursiefen
mesh_terms: D015415:Biomarkers / Q000032:analysis*; D032921:Consensus; D005123:Eye / Q000098:blood supply*; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods*; D042601:Lymphatic Vessels / Q000737:chemistry* / Q000276:immunology
chemical_list: D015415:Biomarkers
keywords: immune privilege; immunocytochemistry; lymphatics