title: Flash generation of α-(trifluoromethyl)vinyllithium and application to continuous flow three-component synthesis of α-trifluoromethylamides.
abstract: α-(Trifluoromethyl)vinyllithium was generated and used for the reaction with electrophiles at -78 °C in a flow microreactor although the batch reaction should be carried out at ca. -100 °C, and the method was applied to continuous flow three-component synthesis of α-trifluoromethylamides.
authors.affiliation: Kyoto University, Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Nishikyo-ku, Kyoto, Japan. yoshida@sbchem.kyoto-u.ac.jp.
authors.forename: Aiichiro
authors.initials: A
authors.lastname: Nagaki
authors.forename: Shinya
authors.initials: S
authors.lastname: Tokuoka
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Yoshida