title: Modular polyketide synthases (PKSs): a new model fits all?
abstract: Step-by-step to great diversity: With the potential to synthesize multi-millions of bioactive compounds, modular polyketide synthases (PKSs) are of great importance. In this Highlight, new developments in the understanding of the structure and function of these proteins are reviewed.
authors.affiliation: Institute for Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Cluster of Excellence "Macromolecular Complexes", Goethe University Frankfurt, Max-von-Laue-Strasse 15, 60438 Frankfurt/Main (Germany).
authors.forename: Alexander
authors.initials: A
authors.lastname: Rittner
authors.forename: Martin
authors.initials: M
authors.lastname: Grininger
mesh_terms: D000818:Animals; D006801:Humans; D008958:Models, Molecular; D048630:Polyketide Synthases / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D048630:Polyketide Synthases
keywords: cryo-EM; fatty acids; multienzymes; natural products; polyketides