title: Treatment Outcome of Tuberculosis Patients Registered at DOTS Centre in Ogbomoso, Southwestern Nigeria: A 4-Year Retrospective Study.
abstract: Background Information. Monitoring outcome of tuberculosis treatment and understanding the specific reasons for unsuccessful treatment outcome are important in evaluating the effectiveness of tuberculosis control program. This study investigated tuberculosis treatment outcomes and predictors for unsuccessful treatment outcome in Ogbomoso town, Southwestern Nigeria. Methodology. Medical records of all tuberculosis patients registered from January 2008 to December 2011 in 5 Local Government areas, Ogbomoso, Southwestern Nigeria, were reviewed. Treatment outcome and tuberculosis type were categorized according to the national tuberculosis control guideline. Bivariate analysis was used to analyse the association between treatment outcome and potential predictor variables. Results. Out of the 965 total TB patients (579 males and 386 females) with mean age 42.4 ± 1.9 years, 866 (89.74%) were categorized as pulmonary tuberculosis and 109 (11.30%) as extrapulmonary tuberculosis. Treatment outcome among total 914 subjects was as follows: 304 (33.26%) patients got cured, 477 (52.19%) completed treatment, 87 (9.52%) died, 9 (0.98%) defaulted, and 1 (0.11%) failed treatment while 36 (3.94%) were transferred out. Higher treatment success rate was associated with those on Category 1 treatment (P < 0.05). Conclusion. The treatment success rate of tuberculosis patients was high (85.45%) compared to national target. However, certain proportion of patients died (9.52%) and defaulted (0.98%), which is a serious public health concern that needs to be addressed urgently.
authors.affiliation: Department of Community Medicine, Ladoke Akintola University Teaching Hospital, Ogbomoso, Nigeria.
authors.forename: Olarewaju
authors.initials: O
authors.lastname: Sunday
authors.affiliation: Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, UK.
authors.forename: Olanrewaju
authors.initials: O
authors.lastname: Oladimeji
authors.affiliation: Department of Community Medicine, Ladoke Akintola University Teaching Hospital, Ogbomoso, Nigeria.
authors.forename: Folorunso
authors.initials: F
authors.lastname: Ebenezer
authors.affiliation: Department of Community Medicine, Ladoke Akintola University Teaching Hospital, Ogbomoso, Nigeria.
authors.forename: Babatunde
authors.initials: B
authors.lastname: Akintunde
authors.affiliation: Department of Community Medicine, Ladoke Akintola University Teaching Hospital, Ogbomoso, Nigeria.
authors.forename: Temitayo-Oboh
authors.initials: TO
authors.lastname: Abiola
authors.affiliation: Department of Community Medicine, Ladoke Akintola University Teaching Hospital, Ogbomoso, Nigeria.
authors.forename: Abdulsalam
authors.initials: A
authors.lastname: Saliu
authors.affiliation: Department of Medical Microbiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.
authors.forename: Oluwatoyin
authors.initials: O
authors.lastname: Abiodun