title: A disseminated variant of pancreatic serous cystadenoma causing obstructive jaundice, a very rare entity: a case report and review of the literature.
abstract: BACKGROUND
  Microcystic adenoma or serous cystadenoma (SCA) is an uncommon tumor type, accounting for only 1-2% of pancreatic exocrine neoplasms. Usually unifocal, SCAs present as single, large, well-demarcated, multiloculated, cystic tumors, 1-25 cm in size.
  
  
  METHODS
  A 73-year-old man initially presented with epigastric abdominal pain and was diagnosed with SCA involving the whole pancreas. Eleven months later, he presented with obstructive jaundice, and total pancreatectomy was performed. The removed tissue allowed histological verification of pancreatic SCA. Histopathological examination showed both microcysts and macrocysts, lined by cuboidal epithelium, with optically clear cytoplasm and the absence of detectable mitosis or necrosis.
  
  
  CONCLUSIONS
  Thus, although relatively rare, pancreatic SCA is one of the differential diagnoses of epigastric abdominal pain; we recommend early surgical intervention for symptomatic pancreatic SCA.
authors.affiliation: Department of Surgery, Taif University, PO Box 888, Taif 21947, Kingdom of Saudi Arabia. Jiffrybilal@hotmail.com.
authors.forename: Bilal O
authors.initials: BO
authors.lastname: Al-Jiffry
authors.forename: Fares
authors.initials: F
authors.lastname: Rayzah
authors.forename: Samah H
authors.initials: SH
authors.lastname: Khayat
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000368:Aged; D049448:Cholangiopancreatography, Magnetic Resonance; D018293:Cystadenoma, Serous / Q000150:complications* / Q000473:pathology / Q000601:surgery; D006801:Humans; D041781:Jaundice, Obstructive / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D008297:Male; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D011237:Predictive Value of Tests; D012307:Risk Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome