title: Vancomycin therapeutic drug monitoring in cerebrospinal fluid.
abstract: Vancomycin penetrates poorly through the blood-brain barrier. Determination of vancomycin concentration in plasma is recommended. In contrast, its determination in cerebrospinal fluid (CSF) is rarely performed. We report the case of a 74-year-old man with post traumatic meningitis with vancomycin concentration measured in CSF.
authors.affiliation: Service de pharmacologie clinique, Centre national de pharmacovigilance, Tunis, Tunisie - Université de Tunis El Manar, Faculté de médecine, Tunis, Tunisie.
authors.forename: Imen
authors.initials: I
authors.lastname: Aouinti
authors.affiliation: Service de pharmacologie clinique, Centre national de pharmacovigilance, Tunis, Tunisie - Université de Tunis El Manar, Faculté de médecine, Tunis, Tunisie.
authors.forename: Rim
authors.initials: R
authors.lastname: Charfi
authors.affiliation: Service de pharmacologie clinique, Centre national de pharmacovigilance, Tunis, Tunisie - Université de Tunis El Manar, Faculté de médecine, Tunis, Tunisie.
authors.forename: Sameh
authors.initials: S
authors.lastname: Trabelsi
authors.affiliation: Service de pharmacologie clinique, Centre national de pharmacovigilance, Tunis, Tunisie - Université de Tunis El Manar, Faculté de médecine, Tunis, Tunisie.
authors.forename: Emna
authors.initials: E
authors.lastname: Gaïes
authors.affiliation: Service de pharmacologie clinique, Centre national de pharmacovigilance, Tunis, Tunisie - Université de Tunis El Manar, Faculté de médecine, Tunis, Tunisie.
authors.forename: Issam
authors.initials: I
authors.lastname: Salouage
authors.affiliation: Service de pharmacologie clinique, Centre national de pharmacovigilance, Tunis, Tunisie.
authors.forename: Nadia
authors.initials: N
authors.lastname: Jebabli
authors.affiliation: Service de pharmacologie clinique, Centre national de pharmacovigilance, Tunis, Tunisie.
authors.forename: Hanène
authors.initials: H
authors.lastname: El Jebari
authors.affiliation: Service de pharmacologie clinique, Centre national de pharmacovigilance, Tunis, Tunisie - Université de Tunis El Manar, Faculté de médecine, Tunis, Tunisie.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Lakhal
authors.affiliation: Service de pharmacologie clinique, Centre national de pharmacovigilance, Tunis, Tunisie - Université de Tunis El Manar, Faculté de médecine, Tunis, Tunisie.
authors.forename: Anis
authors.initials: A
authors.lastname: Klouz
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000134:cerebrospinal fluid* / Q000627:therapeutic use; D001930:Brain Injuries / Q000134:cerebrospinal fluid / Q000188:drug therapy; D016903:Drug Monitoring / Q000379:methods*; D006801:Humans; D008297:Male; D016920:Meningitis, Bacterial / Q000134:cerebrospinal fluid* / Q000188:drug therapy; D014640:Vancomycin / Q000134:cerebrospinal fluid* / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin