title: Concurrent chronic lymphocytic leukemia and merkel cell carcinoma in primary skin tumor and metastatic lymph node.
abstract: Association between chronic lymphocytic leukemia and other malignancies has been known for a long time. This epidemiological phenomenon is explained by immunosuppression caused by disease itself or by the applied therapy. Merkel cell carcinoma is a rare malignant tumor of the skin of neuroendocrine origin diagnosed almost exclusively in immunocompromised host. We presented an unique case of coexisting infiltration of chronic lymphocytic leukemia cells within primary cutaneous Merkel cell carcinoma and metastatic lymph node in young HIV-negative female patient.
authors.affiliation: Department for Medical Oncology, Oncology Institute of Vojvodina, Put Dr Goldmana 4, Sremska Kamenica, 21204 Novi Sad, Serbia ; Medical Faculty, University of Novi Sad, Novi Sad, Serbia.
authors.forename: Lazar
authors.initials: L
authors.lastname: Popovic
authors.affiliation: Department for Medical Oncology, Oncology Institute of Vojvodina, Put Dr Goldmana 4, Sremska Kamenica, 21204 Novi Sad, Serbia ; Medical Faculty, University of Novi Sad, Novi Sad, Serbia.
authors.forename: Darjana
authors.initials: D
authors.lastname: Jovanovic
authors.affiliation: Department for Medical Oncology, Oncology Institute of Vojvodina, Put Dr Goldmana 4, Sremska Kamenica, 21204 Novi Sad, Serbia.
authors.forename: Dragana
authors.initials: D
authors.lastname: Petrovic
authors.affiliation: Department for Medical Oncology, Oncology Institute of Vojvodina, Put Dr Goldmana 4, Sremska Kamenica, 21204 Novi Sad, Serbia ; Medical Faculty, University of Novi Sad, Novi Sad, Serbia.
authors.forename: Zoran
authors.initials: Z
authors.lastname: Nikin
authors.affiliation: Department for Medical Oncology, Oncology Institute of Vojvodina, Put Dr Goldmana 4, Sremska Kamenica, 21204 Novi Sad, Serbia ; Medical Faculty, University of Novi Sad, Novi Sad, Serbia.
authors.forename: Gorana
authors.initials: G
authors.lastname: Matovina-Brko
authors.affiliation: Department for Medical Oncology, Oncology Institute of Vojvodina, Put Dr Goldmana 4, Sremska Kamenica, 21204 Novi Sad, Serbia ; Medical Faculty, University of Novi Sad, Novi Sad, Serbia.
authors.forename: Jasna
authors.initials: J
authors.lastname: Trifunovic
authors.affiliation: Department for Medical Oncology, Oncology Institute of Vojvodina, Put Dr Goldmana 4, Sremska Kamenica, 21204 Novi Sad, Serbia ; Medical Faculty, University of Novi Sad, Novi Sad, Serbia.
authors.forename: Ivana
authors.initials: I
authors.lastname: Kolarov-Bjelobrk
keywords: Chronic lymphocytic leukemia; Merkel cell carcinoma; Secondary malignancy