title: International multicentre psychometric evaluation of patient-reported outcome data for the treatment of Peyronie's disease.
abstract: OBJECTIVE
  To compare patient-reported outcomes (PROs) of surgical correction of Peyronie's disease (PD) with the Nesbit procedure, plaque incision and grafting, and the insertion of a malleable penile implant after surgical correction of penile curvature.
  
  
  METHODS
  We performed a retrospective review of men who underwent surgical correction of PD between January 2010 and December 2012 at six international centres. Treatment-related PROs and satisfaction were evaluated with a non-validated questionnaire.
  
  
  RESULTS
  The response rate to the questionnaire was 70.9%, resulting in a study cohort of 206 patients. The Nesbit procedure, plaque incision with grafting, or implantation of a malleable penile prosthesis was performed in 50, 48, and 108 patients, respectively. Overall, 79.1% reported a subjective loss of penile length due to PD preoperatively (range 2.1-3.2 cm). Those patients treated with a malleable penile implant reported the greatest subjective penile length loss, due to PD. A subjective loss of penile length of >2.5 cm resulted in reduced preoperative sex ability. Postoperatively, 78.0%, 29.2% and 24.1% patients in the Nesbit, grafting, and implant groups reported a postoperative, subjective loss of penile length (range 0.4-1.2 cm), with 86.3%, 78.6%, and 82.1% of the patients in each group, respectively, being bothered by the loss of length.
  
  
  CONCLUSIONS
  Penile length loss due to PD affects most patients. Further penile length loss due to the surgical correction leads to bother among the affected patients, irrespective of the magnitude of the loss. The Nesbit procedure was associated with the highest losses in penile length. In patients with PD and severe erectile dysfunction, a concomitant lengthening procedure may be offered to patients to help overcome the psychological burden caused by the loss of penile length.
authors.affiliation: Department of Obstetrics and Gynecology, Medical University of Vienna, Vienna, Austria.
authors.forename: Verena
authors.initials: V
authors.lastname: Kueronya
authors.forename: Arkadius
authors.initials: A
authors.lastname: Miernik
authors.forename: Slavisa
authors.initials: S
authors.lastname: Stupar
authors.forename: Vladimir
authors.initials: V
authors.lastname: Kojovic
authors.forename: Georgios
authors.initials: G
authors.lastname: Hatzichristodoulou
authors.forename: Paulo H
authors.initials: PH
authors.lastname: Egydio
authors.forename: Georgi
authors.initials: G
authors.lastname: Tosev
authors.forename: Marco
authors.initials: M
authors.lastname: Falcone
authors.forename: Francesco
authors.initials: F
authors.lastname: De Luca
authors.forename: Demir
authors.initials: D
authors.lastname: Mulalic
authors.forename: Miroslav
authors.initials: M
authors.lastname: Djordjevic
authors.forename: Martin
authors.initials: M
authors.lastname: Schoenthaler
authors.forename: Christian
authors.initials: C
authors.lastname: Fahr
authors.forename: Franklin E
authors.initials: FE
authors.lastname: Kuehhas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D006801:Humans; D038622:Internationality; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D019935:Penile Implantation; D010411:Penile Induration / Q000601:surgery*; D011594:Psychometrics; D012189:Retrospective Studies; D057566:Self Report; D016896:Treatment Outcome; D013521:Urologic Surgical Procedures, Male / Q000379:methods; D055815:Young Adult
keywords: Nesbit; Peyronie's disease; grafting; patient-related outcome; penile prosthesis; treatment