title: Concurrent primary sclerosing cholangitis and eosinophilic colitis.
abstract: A 39-year-old man presented with diarrhea and abdominal pain. At 26 years of age, he was found to have eosinophilia and abnormal liver function parameters, for which prednisolone therapy was started. He subsequently underwent a liver biopsy and endoscopic retrograde cholangiopancreatography, and received a diagnosis of primary sclerosing cholangitis (PSC). On presentation to our hospital, he was further diagnosed with eosinophilic colitis based on aggravation of diarrhea and severe eosinophilic infiltration in the colonic mucosa. We herein report a rare case of concurrent PSC and eosinophilic colitis.
authors.affiliation: Department of Gastroenterology and Rheumatology, Fukushima Medical University, Japan.
authors.forename: Naohiko
authors.initials: N
authors.lastname: Gunji
authors.forename: Kyoko
authors.initials: K
authors.lastname: Katakura
authors.forename: Atsushi
authors.initials: A
authors.lastname: Takahashi
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Fujiwara
authors.forename: Ryoma
authors.initials: R
authors.lastname: Suzuki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Watanabe
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Ohira
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001706:Biopsy; D002760:Cholangiopancreatography, Endoscopic Retrograde; D015209:Cholangitis, Sclerosing / Q000150:complications* / Q000175:diagnosis; D003092:Colitis / Q000150:complications* / Q000175:diagnosis; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000209:etiology; D004802:Eosinophilia / Q000150:complications* / Q000175:diagnosis; D019693:Hepatitis, Autoimmune / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D008099:Liver / Q000473:pathology; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone