title: Serial Spectral Domain Ocular Coherence Tomography Measurement of Outer Nuclear Layer Thickness in Rhegmatogenous Retinal Detachment Repair.
abstract: BACKGROUND
  The outer nuclear layer (ONL) contains mostly photoreceptor bodies and reduced post-operative ONL thickness (ONLT) is associated with poor visual outcome in rhegmatogenous retinal detachment (RRD).
  
  
  METHODS
  Spectral domain ocular coherence tomography was recorded before and 6 weeks following RRD repair in 27 consecutive patients.
  
  
  RESULTS
  The repair consisted of combined 20-guage pars plana vitrectomy (PPV) and encirclement in 66.7% of cases, 22.2% underwent PPV alone and 11.1% scleral buckle alone. The mean (± standard deviation) ONLT was reduced in detached retinae (94.1 ± 31.1 microns) compared to the unaffected eye (119.5 ± 26.8 microns). Postoperatively the ONLT increased to 103.3 (± 32.8) microns. ONLT at presentation in the affected eye is significantly and positively correlated with the final ONLT in the affected eye (Pearson's correlation: r = 0.80, p = 0.029).
  
  
  CONCLUSIONS
  The finding that ONLT is reduced in detached retinae carries implications for visual prognosis.
authors.affiliation: a The Royal Victoria Eye and Ear Hospital , Dublin , Ireland.
authors.forename: Ian
authors.initials: I
authors.lastname: Dooley
authors.affiliation: a The Royal Victoria Eye and Ear Hospital , Dublin , Ireland.
authors.forename: Max
authors.initials: M
authors.lastname: Treacy
authors.affiliation: a The Royal Victoria Eye and Ear Hospital , Dublin , Ireland.
authors.forename: Micheal
authors.initials: M
authors.lastname: O'Rourke
authors.affiliation: a The Royal Victoria Eye and Ear Hospital , Dublin , Ireland.
authors.forename: Ibrar
authors.initials: I
authors.lastname: Khaild
authors.affiliation: a The Royal Victoria Eye and Ear Hospital , Dublin , Ireland.
authors.forename: Dara
authors.initials: D
authors.lastname: Kilmartin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D058450:Endotamponade; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment / Q000503:physiopathology* / Q000601:surgery*; D055351:Retinal Neurons / Q000473:pathology*; D012189:Retrospective Studies; D012591:Scleral Buckling; D058471:Subretinal Fluid; D013459:Sulfur Hexafluoride / Q000008:administration & dosage; D041623:Tomography, Optical Coherence; D014786:Vision Disorders / Q000503:physiopathology*; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy
chemical_list: D013459:Sulfur Hexafluoride
keywords: Macula; OCT; ONL; RASTER; macula-off; macula-on; ocular coherence tomography; outer nuclear layer; retinal detachment; spectral domain