title: [Multimodal imaging in the diagnosis of acute macular neuroretinopathy].
abstract: BACKGROUND
  Acute macular neuroretinopathy is a retinal disease, usually presenting with a "normal fundus". Thus, this condition can be mistaken for optic neuropathy. Herein we present five clinical cases of patients affected with acute macular neuroretinopathy; one of them is a retrospective diagnosis while the others were diagnosed on initial examination. In the five cases, multimodal imaging with infrared photography and OCT helped to establish the diagnosis.
  
  
  METHODS
  Retrospective study of five clinical cases. Initial and final best visual acuities as well as infrared and OCT imaging were collected for all patients.
  
  
  RESULTS
  All patients initially reported a visual disturbance associated with a more or less severe decrease in visual acuity. Infrared imaging showed a dark, perifoveolar appearance of the lesions. In all cases, OCT images showed thickening and hyperreflectivity of the outer plexiform layer, extending towards the outer retinal layers.
  
  
  CONCLUSIONS
  Acute macular neuroretinopathy is a clinical entity that has been long-described, which now benefits widely from new imaging technologies, allowing an earlier and more accurate diagnosis, but calling into question the actual name of this condition. The exact pathophysiology of the condition remains nonetheless incompletely elucidated.
authors.affiliation: Centre de la rétine, hôpital Paule-de-Viguier, CHU de Toulouse, 330, avenue de Grande-Bretagne TSA 70034, 31059 Toulouse cedex 9, France; Laboratoire GR2DE, Inserm UMRS1043, centre de physiopathologie de Toulouse Purpan, place Baylac, 31059 Toulouse, France.
authors.forename: C
authors.initials: C
authors.lastname: Tolou
authors.affiliation: Centre de la rétine, hôpital Paule-de-Viguier, CHU de Toulouse, 330, avenue de Grande-Bretagne TSA 70034, 31059 Toulouse cedex 9, France.
authors.forename: L
authors.initials: L
authors.lastname: Mahieu
authors.affiliation: Centre de la rétine, hôpital Paule-de-Viguier, CHU de Toulouse, 330, avenue de Grande-Bretagne TSA 70034, 31059 Toulouse cedex 9, France.
authors.forename: L
authors.initials: L
authors.lastname: Salmon
authors.affiliation: Centre de la rétine, hôpital Paule-de-Viguier, CHU de Toulouse, 330, avenue de Grande-Bretagne TSA 70034, 31059 Toulouse cedex 9, France.
authors.forename: S
authors.initials: S
authors.lastname: Hamid
authors.affiliation: Centre de la rétine, hôpital Paule-de-Viguier, CHU de Toulouse, 330, avenue de Grande-Bretagne TSA 70034, 31059 Toulouse cedex 9, France.
authors.forename: C
authors.initials: C
authors.lastname: Suarez
authors.affiliation: Centre de la rétine, hôpital Paule-de-Viguier, CHU de Toulouse, 330, avenue de Grande-Bretagne TSA 70034, 31059 Toulouse cedex 9, France.
authors.forename: D
authors.initials: D
authors.lastname: Garcia
authors.affiliation: Centre de la rétine, hôpital Paule-de-Viguier, CHU de Toulouse, 330, avenue de Grande-Bretagne TSA 70034, 31059 Toulouse cedex 9, France.
authors.forename: V
authors.initials: V
authors.lastname: Pagot-Mathis
authors.affiliation: Centre de la rétine, hôpital Paule-de-Viguier, CHU de Toulouse, 330, avenue de Grande-Bretagne TSA 70034, 31059 Toulouse cedex 9, France.
authors.forename: C
authors.initials: C
authors.lastname: Gomane
authors.affiliation: Centre de la rétine, hôpital Paule-de-Viguier, CHU de Toulouse, 330, avenue de Grande-Bretagne TSA 70034, 31059 Toulouse cedex 9, France.
authors.forename: A
authors.initials: A
authors.lastname: Berot
authors.affiliation: Centre de la rétine, hôpital Paule-de-Viguier, CHU de Toulouse, 330, avenue de Grande-Bretagne TSA 70034, 31059 Toulouse cedex 9, France; Laboratoire GR2DE, Inserm UMRS1043, centre de physiopathologie de Toulouse Purpan, place Baylac, 31059 Toulouse, France.
authors.forename: F
authors.initials: F
authors.lastname: Malecaze
authors.affiliation: Centre de la rétine, hôpital Paule-de-Viguier, CHU de Toulouse, 330, avenue de Grande-Bretagne TSA 70034, 31059 Toulouse cedex 9, France; Laboratoire GR2DE, Inserm UMRS1043, centre de physiopathologie de Toulouse Purpan, place Baylac, 31059 Toulouse, France. Electronic address: vincesoler@yahoo.fr.
authors.forename: V
authors.initials: V
authors.lastname: Soler
mesh_terms: D000208:Acute Disease; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007259:Infrared Rays; D064847:Multimodal Imaging / Q000379:methods*; D009901:Optic Nerve Diseases / Q000175:diagnosis; D011237:Predictive Value of Tests; D012164:Retinal Diseases / Q000175:diagnosis*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D055815:Young Adult
keywords: Acute macular neuroretinopathy; Couche plexiforme externe; Imagerie multimodale; Infrared; Infrarouge; Multimodal imaging; Neurorétinopathie maculaire aiguë; OCT; Outer plexiform layer