title: Ruthenium-catalyzed highly regio- and stereoselective hydroarylation of aromatic sulfoxides with alkynes via C-H bond activation.
abstract: Chelation-assisted alkenylation at the ortho C-H bond of aromatic sulfoxides with alkynes in the presence of a ruthenium catalyst, AgSbF6 and pivalic acid yielding trisubstituted alkenes in good to excellent yields in a highly regio- and stereoselective manner via a deprotonation metalation pathway is described. Later, ortho-alkenylated aromatic sulfoxides were converted into α-acyloxy-thioether and a 2,3-disubstituted benzothiophene derivative.
authors.affiliation: Department of Chemistry, Indian Institute of Science Education and Research, Pune 411021, India. mjeganmohan@iiserpune.ac.in.
authors.forename: Kishor
authors.initials: K
authors.lastname: Padala
authors.forename: Masilamani
authors.initials: M
authors.lastname: Jeganmohan