title: Occlusive gloves and skin conditions: is there a problem? Results of a cross-sectional study in a semiconductor company.
abstract: BACKGROUND
  Although there is poor scientific evidence that working with occlusive gloves is as damaging as wet work, prolonged glove occlusion is considered to be a risk factor for developing hand eczema similar to wet work.
  
  
  OBJECTIVE
  To assess the effects of wearing occlusive gloves during the whole working day, without exposure to any additional hazardous substances, on skin condition and skin barrier function.
  
  
  METHODS
  We investigated 323 employees of a semiconductor production company in Germany: 177 clean-room workers wearing occlusive gloves during the whole shift (exposed group) and 146 employees working in administration (control group). A standardized interview was performed, the skin condition of both hands was studied using the quantitative skin score HEROS, and transepidermal water loss (TEWL) and stratum corneum hydration were measured.
  
  
  RESULTS
  There was no significant difference in skin condition between the two subgroups. Values for TEWL and corneometry were significantly higher in exposed participants (P < 0·05). However, the TEWL values were similar to control values if participants took off the occlusive gloves at least 30 min before the measurement. Hence, the effect of occlusion on skin barrier function seems to be transient.
  
  
  CONCLUSIONS
  Prolonged wearing of occlusive gloves with clean hands and without exposure to additional hazardous substances does not seem to affect the skin negatively.
authors.affiliation: Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, D-91054, Erlangen, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Weistenhöfer
authors.forename: M
authors.initials: M
authors.lastname: Wacker
authors.forename: F
authors.initials: F
authors.lastname: Bernet
authors.forename: W
authors.initials: W
authors.lastname: Uter
authors.forename: H
authors.initials: H
authors.lastname: Drexler
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D009783:Dermatitis, Occupational / Q000209:etiology* / Q000503:physiopathology; D004485:Eczema / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D017575:Gloves, Protective / Q000009:adverse effects*; D006229:Hand Dermatoses / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010808:Physical Examination; D012666:Semiconductors; D012879:Skin Physiological Phenomena; D014870:Water Loss, Insensible / Q000502:physiology; D055815:Young Adult