title: [Vaccination is not always sufficient to prevent vertical transmission of hepatitis B virus].
abstract: Routine screening of pregnant women for infection with hepatitis B virus and active-passive immunization of newborns resulted in a dramatic decline in vertical transmission of hepatitis B. A recent study in the Annals of Internal Medicine identified factors associated with failure of active-passive immunization of newborns from hepatitis B virus infected mothers. A further decline in the incidence of vertical transmission of hepatitis B virus may be expected when referral for and initiation of antiviral therapy in the last trimester of pregnancy for selected patients can be optimized.
authors.affiliation: Erasmus MC, afd. Maag-Darm-Leverziekten, Rotterdam.
authors.forename: Erik H J C
authors.initials: EH
authors.lastname: Buster
authors.forename: Robert A
authors.initials: RA
authors.lastname: de Man
mesh_terms: D005260:Female; D006509:Hepatitis B / Q000517:prevention & control* / Q000635:transmission; D017325:Hepatitis B Vaccines / Q000008:administration & dosage* / Q000276:immunology; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000517:prevention & control* / Q000821:virology; D011263:Pregnancy Trimester, Third
chemical_list: D017325:Hepatitis B Vaccines