title: [Squamous cell carcinoma in ulcer after bacille Calmette-Guérin vaccination].
abstract: Marjolin's ulcer is an aggressive squamous cell carcinoma (SCC) found in chronically inflamed skin. SCC has been reported in smallpox vaccination sites, whereas basal cell carcinomas are more common in scar after bacille Calmette-Guérin (BCG) vaccination. A 72-year-old man presented with a chronic ulcer at the site of his childhood BCG vaccination. At the time of examination, a 3 × 1.5 cm fleshy and secreting ulcer was found on the shoulder. Biopsy revealed SCC, and the tumour was surgically removed. In conclusion, chronic ulcers, especially those originating in chronically inflamed skin, should be regularly biopsied to assure that malignant transformation has not occurred.
authors.forename: Rikke Maria
authors.initials: RM
authors.lastname: Nielsen
authors.forename: Flemming
authors.initials: F
authors.lastname: Andersen
authors.affiliation: Det Sundhedsvidenskabelige Fakultet, Syddansk Universitet, Winsløwsgade 19, 5000 Odense. salskov@ki.au.dk.
authors.forename: Maria Luise
authors.initials: ML
authors.lastname: Salskov-Iversen
mesh_terms: D000368:Aged; D001500:BCG Vaccine / Q000009:adverse effects*; D002294:Carcinoma, Squamous Cell / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D012878:Skin Neoplasms / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D012883:Skin Ulcer / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery
chemical_list: D001500:BCG Vaccine