title: Epstein-Barr virus-associated smooth muscle tumors in AIDS patients: a largest case (series).
abstract: This study aimed to determine the outcomes of Epstein-Barr virus (EBV)-associated smooth muscle tumors (SMTs) in AIDS patients at King Chulalongkorn Memorial Hospital, Bangkok, Thailand, treated from 2001-2011. Of the 17 patients, there were five men with a median CD4 count of 26 cells/μL. Eight and nine patients had single and multiple sites, respectively. The most common site was the cranial epidura (58.8%). All patients had EBV within the tumor. Seven patients underwent surgery. The median follow-up was one year. The mortality rate was 41.2%. All patients with undetectable HIV viremia survived. This is the largest case series regarding EBV-associated SMTs in AIDS patients with a long follow-up period.
authors.affiliation: Division of Infectious Diseases, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Thailand.
authors.forename: Ratima
authors.initials: R
authors.lastname: Issarachaikul
authors.forename: Shanop
authors.initials: S
authors.lastname: Shuangshoti
authors.forename: Chusana
authors.initials: C
authors.lastname: Suankratay
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000821:virology; D000328:Adult; D018791:CD4 Lymphocyte Count; D002675:Child, Preschool; D020031:Epstein-Barr Virus Infections / Q000150:complications* / Q000401:mortality / Q000821:virology; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000821:virology; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D018235:Smooth Muscle Tumor / Q000150:complications* / Q000401:mortality / Q000821:virology; D013785:Thailand