title: Solution structure of a cucurbit[8]uril induced compact supramolecular protein dimer.
abstract: Supramolecular assembly of a beta-barrel protein via cucurbit[8]uril results in compact z-shaped protein dimers. SAXS data reveal the formation of a well ordered protein dimer, notwithstanding being connected by a reversible and flexible peptide linker, and highlight the supramolecular induced interplay of the proteins, analogous to covalently linked proteins.
authors.affiliation: Department of Biomedical Engineering, Eindhoven University of Technology, Den Dolech 2, 5612 AZ, Eindhoven, The Netherlands. l.brunsveld@tue.nl.
authors.forename: Dung T
authors.initials: DT
authors.lastname: Dang
authors.forename: Ralph P G
authors.initials: RP
authors.lastname: Bosmans
authors.forename: Christian
authors.initials: C
authors.lastname: Moitzi
authors.forename: Ilja K
authors.initials: IK
authors.lastname: Voets
authors.forename: Luc
authors.initials: L
authors.lastname: Brunsveld
mesh_terms: D001426:Bacterial Proteins / Q000737:chemistry*; D001952:Bridged-Ring Compounds / Q000737:chemistry*; D007093:Imidazoles / Q000737:chemistry*; D008164:Luminescent Proteins / Q000737:chemistry*; D008958:Models, Molecular; D008970:Molecular Weight; D055503:Protein Multimerization; D017433:Protein Structure, Secondary; D011993:Recombinant Fusion Proteins / Q000737:chemistry*; D053838:Scattering, Small Angle; D012996:Solutions; D014961:X-Ray Diffraction; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils
chemical_list: D001426:Bacterial Proteins; D001952:Bridged-Ring Compounds; D007093:Imidazoles; D008164:Luminescent Proteins; D011993:Recombinant Fusion Proteins; D012996:Solutions; C507198:cucurbit(8)uril; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils; C054562:yellow fluorescent protein, Bacteria