title: Direct enantiospecific substitution of primary α-aminoalkylferrocenes via Lewis acid-catalyzed C-N bond cleavage.
abstract: Highly enantioenriched primary α-aminoalkylferrocenes were found to undergo zinc chloride-catalyzed substitution with various carbon, nitrogen, and sulfur nucleophiles in an enantiospecific fashion through C-N bond cleavage. The reaction tolerates air and moisture and exhibits high atom-economy by releasing ammonia as the sole byproduct.
authors.affiliation: Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China. tiansk@ustc.edu.cn.
authors.forename: Meng-Guang
authors.initials: MG
authors.lastname: Zhou
authors.forename: Wen-Zhao
authors.initials: WZ
authors.lastname: Zhang
authors.forename: Shi-Kai
authors.initials: SK
authors.lastname: Tian