title: Regioselective C-H imidation of five-membered heterocyclic compounds through a metal catalytic or organocatalytic approach.
abstract: An efficient method for the synthesis of 2-amino and β-amino five-membered heterocyclic derivatives that are closely related to a variety of biologically active natural products is described. Regioselectivity was achieved through a metal catalytic or organocatalytic approach. Preliminary studies on the reaction mechanism suggest a radical imidation pathway; however, further studies are needed to verify the mechanism.
authors.affiliation: College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang, Henan 455000 (P. R. China).
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.forename: Kai
authors.initials: K
authors.lastname: Sun
authors.forename: Yunhe
authors.initials: Y
authors.lastname: Lv
authors.forename: Fengji
authors.initials: F
authors.lastname: Ma
authors.forename: Gang
authors.initials: G
authors.lastname: Li
authors.forename: Donghui
authors.initials: D
authors.lastname: Li
authors.forename: Zhonghong
authors.initials: Z
authors.lastname: Zhu
authors.forename: Yongqing
authors.initials: Y
authors.lastname: Jiang
authors.forename: Feng
authors.initials: F
authors.lastname: Zhao
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry*; D007094:Imides / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D006576:Heterocyclic Compounds, 4 or More Rings; D007094:Imides; D009942:Organometallic Compounds; D003300:Copper
keywords: CH activation; catalysis; heterocycles; imidation; site-selective