title: Bridging lipid metabolism and innate host defense.
abstract: Host- and pathogen-derived lipids share clearance mechanisms that pinpoint PCSK9 as a plausible target for the treatment of some patients with sepsis (Walley et al., this issue).
authors.affiliation: Department of Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario M5B 1W8, Canada. Department of Critical Care Medicine and the Keenan Research Centre for Biomedical Science of the Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto, Ontario M5B 1W8, Canada.
authors.forename: Claudia
authors.initials: C
authors.lastname: dos Santos
authors.affiliation: Department of Critical Care Medicine and the Keenan Research Centre for Biomedical Science of the Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto, Ontario M5B 1W8, Canada. Department of Surgery, St. Michael's Hospital, University of Toronto, Toronto, Ontario M5B 1W8, Canada. marshallj@smh.ca.
authors.forename: John C
authors.initials: JC
authors.lastname: Marshall
mesh_terms: D000818:Animals; D006801:Humans; D007113:Immunity, Innate; D008297:Male; D043484:Proprotein Convertases / Q000378:metabolism*; D012697:Serine Endopeptidases / Q000378:metabolism*; D012772:Shock, Septic / Q000276:immunology* / Q000378:metabolism*
chemical_list: D043484:Proprotein Convertases; D012697:Serine Endopeptidases