title: Relative Risk for HIV Infection Among Men Who Have Sex with Men Engaging in Different Roles in Anal Sex: A Systematic Review and Meta-analysis on Global Data.
abstract: We systematically reviewed and meta-analyzed global data on the relative risk for HIV infection among men who have sex with men (MSM) engaging in different roles in anal sex. MSM engaging in receptive anal sex only (MRAI) and MSM engaging in both insertive and receptive anal sex (MIRAI) were 6.9 (95 % CI 5.5-8.6) and 4.3 (95 % CI 3.6-5.3) times more likely to have prevalent HIV compared to MSM engaging in insertive anal sex only (MIAI) in 1981-1985. These figures were 1.8 (95 % CI 1.6-2.0) and 2.2 (95 % CI 2.0-2.4) in 1986-2010. Overall, MRAI and MIRAI were 6.2 (95 % CI 3.3-11.8) and 6.6 (95 % CI 3.8-11.7) times more likely to develop incident HIV infection compared to MIAI. MRAI are at higher risk for HIV infection compared to MIAI. HIV prevalence among men engaging in all roles in anal sex is high enough that all MSM should be aware of potential risk.
authors.affiliation: Wuxi Center for Disease Control and Prevention, Wuxi, Jiangsu, People's Republic of China.
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Meng
authors.forename: Huachun
authors.initials: H
authors.lastname: Zou
authors.forename: Song
authors.initials: S
authors.lastname: Fan
authors.forename: Benfeng
authors.initials: B
authors.lastname: Zheng
authors.forename: Lin
authors.initials: L
authors.lastname: Zhang
authors.forename: Xin
authors.initials: X
authors.lastname: Dai
authors.forename: Minli
authors.initials: M
authors.lastname: Deng
authors.forename: Xuan
authors.initials: X
authors.lastname: Zhang
authors.forename: Bing
authors.initials: B
authors.lastname: Lu
mesh_terms: D000328:Adult; D017280:Condoms / Q000706:statistics & numerical data; D015658:HIV Infections / Q000453:epidemiology*; D018451:Homosexuality, Male / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D015995:Prevalence; D012306:Risk; D012725:Sexual Behavior / Q000523:psychology*; D047568:Unsafe Sex / Q000706:statistics & numerical data*