title: Immune thrombocytopenia (ITP): a rare association of lymph node tuberculosis.
abstract: Although various haematologic abnormalities are known to occur with tuberculosis, association of immune thrombocytopenia with tuberculosis is uncommon. We report a case of retroperitoneal lymph node tuberculosis who presented with ITP. A 76 year old female was admitted to our hospital with oral mucosal bleed and petechial lesions over extremities and abdomen. A diagnosis of immune thrombocytopenia (ITP) was established. Intravenous Anti-D immunoglobulin and Dexamethasone therapy was started, but failed to elicit any sustained platelet response. CT abdomen revealed multiple retroperitoneal lymph nodes with central necrosis. Histopathology (HPE) of these revealed caseating lymphadenitis suggestive of tuberculosis. After 2 months of anti-tuberculous therapy, the platelet counts returned to normal and patient was off all therapy for ITP thereby suggesting likely association between tuberculosis and immune thrombocytopenia.
authors.forename: Anuj P
authors.initials: AP
authors.lastname: Surana
authors.forename: Kishor M
authors.initials: KM
authors.lastname: Shelgikar
authors.forename: Sameer
authors.initials: S
authors.lastname: Melinkeri
authors.forename: Arvind
authors.initials: A
authors.lastname: Phadke
mesh_terms: D000995:Antitubercular Agents / Q000008:administration & dosage; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D013921:Thrombocytopenia / Q000150:complications* / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D014388:Tuberculosis, Lymph Node / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents