title: Unpredictable behavior of breast phyllodes tumors.
abstract: OBJECTIVE
  Phyllodes Tumor is a rare fibroepithelial breast tumor with variable malignant potential. These tumors that currently accepted nomenclature are benign, borderline and malignant according to the World Health Organization. It tends to behave in a benign way but it may undergo a malignant transformation. The purpose of this study was to present our Case load of phyllodes tumor, and evaluate the management and follow-up the behavior of these tumors.
  
  
  METHODS
  36 patients with phyllodes tumor were treated in Bezmialem Vakif University and Okmeydani Training and Research Hospitals analyzed retrospectively. Demographics, presenting symptoms, history, local examination, preoperative clinical diagnosis, treatment, postoperative histopatology, follow-up period were evaluated retrospectively and studied.
  
  
  RESULTS
  A total of 36 patients treated for phyllodes tumor were analyzed. Mean age of the patients was 38 (14-79) and all were females. The presentation of the patients was breast lump in all cases, either as a primary or recurrent lump presentation. The right and left breast were affected 58% and 42% respectively. 34 of these 36 cases are briefly mentioned in this paper but the two cases, one with sarcomatous malignant transformation and the other with fatal metastatic phyllodes tumor in an adolescent female are discussed in detail. The mean duration of the symptomatic mass was 9.8 ± 7.3 months (range 0.5 to 24).
  
  
  CONCLUSIONS
  Phyllodes tumor is a type of tumor that may be benign or malignant. The type with malignant features may be fatal. The tumors diagnosed as benign may transform and become malignant because of unknown reasons and may be an aggressive tumor.
authors.affiliation: Department of Surgery, Medical Faculty, Bezmialem Vakif University, Istanbul, Turkey. ozgurkemik@hotmail.com.
authors.forename: A
authors.initials: A
authors.lastname: Akcakaya
authors.forename: B
authors.initials: B
authors.lastname: Koc
authors.forename: F
authors.initials: F
authors.lastname: Erozgen
authors.forename: N
authors.initials: N
authors.lastname: Memmi
authors.forename: S
authors.initials: S
authors.lastname: Hot
authors.forename: M K
authors.initials: MK
authors.lastname: Yildiz
authors.forename: Z
authors.initials: Z
authors.lastname: Gucin
authors.forename: G
authors.initials: G
authors.lastname: Adas
authors.forename: O
authors.initials: O
authors.lastname: Kemik
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000601:surgery*; D017809:Fatal Outcome; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D018225:Neoplasms, Fibroepithelial / Q000175:diagnosis / Q000601:surgery; D003557:Phyllodes Tumor / Q000175:diagnosis* / Q000601:surgery*; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D055815:Young Adult