title: SASBDB, a repository for biological small-angle scattering data.
abstract: Small-angle X-ray and neutron scattering (SAXS and SANS) are fundamental tools used to study the global shapes of proteins, nucleic acids, macromolecular complexes and assemblies in solution. Due to recent advances in instrumentation and computational methods, the quantity of experimental scattering data and subsequent publications is increasing dramatically. The need for a global repository allowing investigators to locate and access experimental scattering data and associated models was recently emphasized by the wwPDB small-angle scattering task force (SAStf). The small-angle scattering biological data bank (SASBDB) www.sasbdb.org has been designed in accordance with the plans of the SAStf as part of a future federated system of databases for biological SAXS and SANS. SASBDB is a comprehensive repository of freely accessible and fully searchable SAS experimental data and models that are deposited together with the relevant experimental conditions, sample details and instrument characteristics. At present the quality of deposited experimental data and the accuracy of models are manually curated, with future plans to integrate automated systems as the database expands.
authors.affiliation: European Molecular Biology Laboratory, Hamburg Outstation, Notkestr. 85, Geb. 25a, 22603 Hamburg, Germany.
authors.forename: Erica
authors.initials: E
authors.lastname: Valentini
authors.affiliation: European Molecular Biology Laboratory, Hamburg Outstation, Notkestr. 85, Geb. 25a, 22603 Hamburg, Germany a.kikhney@embl-hamburg.de.
authors.forename: Alexey G
authors.initials: AG
authors.lastname: Kikhney
authors.affiliation: European Molecular Biology Laboratory, Hamburg Outstation, Notkestr. 85, Geb. 25a, 22603 Hamburg, Germany.
authors.forename: Gianpietro
authors.initials: G
authors.lastname: Previtali
authors.affiliation: European Molecular Biology Laboratory, Hamburg Outstation, Notkestr. 85, Geb. 25a, 22603 Hamburg, Germany.
authors.forename: Cy M
authors.initials: CM
authors.lastname: Jeffries
authors.affiliation: European Molecular Biology Laboratory, Hamburg Outstation, Notkestr. 85, Geb. 25a, 22603 Hamburg, Germany d.svergun@embl-hamburg.de.
authors.forename: Dmitri I
authors.initials: DI
authors.lastname: Svergun
mesh_terms: D062126:Databases, Chemical; D020407:Internet; D046911:Macromolecular Substances / Q000737:chemistry; D033363:Neutron Diffraction; D053838:Scattering, Small Angle; D014961:X-Ray Diffraction
chemical_list: D046911:Macromolecular Substances