title: MicroRNA-1 in Cardiac Diseases and Cancers.
abstract: MicroRNAs (miRs) are endogenous ≈22-nt non-coding RNAs that participate in the regulation of gene expression at post-transcriptional level. MiR-1 is one of the muscle-specific miRs, aberrant expression of miR-1 plays important roles in many physiological and pathological processes. In this review, we focus on the recent studies about miR-1 in cardiac diseases and cancers. The findings indicate that miR-1 may be a novel, important biomarker, and a potential therapeutic target in cardiac diseases and cancers.
authors.affiliation: Department of Pharmacy, Ruikang Hospital, Guangxi University of Chinese Medicine, Nanning, Guangxi 530011, China.
authors.forename: Jianzhe
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Osteology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China.
authors.forename: Xiaomin
authors.initials: X
authors.lastname: Dong
authors.affiliation: Department of Physiology and pathophysiology, school of Basic Medical Sciences, Jiujiang University, Jiujiang, Jiangxi 332000, China.
authors.forename: Zhongping
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Pharmacy, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China.
authors.forename: Jianhua
authors.initials: J
authors.lastname: Wu
keywords: Cancers; Cardiac diseases; MicroRNA-1