title: Hyperacute ischemic stroke without lesions on diffusion-weighted imaging in a patient treated with rtPA thrombolysis.
abstract: We report a comatose patient with severe neurological deficits who was without spontaneous language or movement. He had a good response to recombinant tissue plasminogen activator (rtPA) thrombolysis even though there were no detectable lesions on diffusion-weighted imaging (DWI). DWI is very sensitive for diagnosing hyperacute ischemic stroke, and rtPA thrombolysis is the best treatment. However, rtPA thrombolysis in ischemic stroke patients without lesions on DWI has rarely been reported.
authors.affiliation: The First Affiliated Hospital, Jinan University Guangzhou, Guangdong, 510632, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Jing
authors.affiliation: The First Affiliated Hospital, Jinan University Guangzhou, Guangdong, 510632, China.
authors.forename: Shijun
authors.initials: S
authors.lastname: Zhang
authors.affiliation: The First Affiliated Hospital, Jinan University Guangzhou, Guangdong, 510632, China.
authors.forename: Jingjing
authors.initials: J
authors.lastname: Tang
authors.affiliation: The First Affiliated Hospital, Jinan University Guangzhou, Guangdong, 510632, China.
authors.forename: Anding
authors.initials: A
authors.lastname: Xu
authors.affiliation: GHM Institute of CNS Regeneration (GHMICR), Jinan University Guangzhou, Guangdong, 510632, China.
authors.forename: Yiwen
authors.initials: Y
authors.lastname: Ruan
authors.affiliation: The First Affiliated Hospital, Jinan University Guangzhou, Guangdong, 510632, China.
authors.forename: Li'an
authors.initials: L
authors.lastname: Huang
keywords: Diffusion-weighted imaging; hyperacute ischemic stroke; recombinant tissue plasminogen activator; thrombolysis