title: A case of fever of unknown origin: necrotizing sarcoid granulomatosis.
abstract: Necrotizing sarcoid granulomatosis is a rare type of vasculitis; its etiology and pathogenesis are still unknown. The disease primarily affects the lungs, although extra-pulmonary involvement has been reported. The typical symptoms are cough, chest pain, dyspnea, and weight loss; high temperatures have been reported in rare cases. We present the case of a 65-year-old woman who was diagnosed with lymph node tuberculosis, for which she received treatment for six months. The patient experienced no improvement in her symptoms, which included fever, weakness and dyspnea. A re-evaluation of previously collected thoracoscopic biopsy material revealed compatibility with necrotizing sarcoid granulomatosis.
authors.affiliation: Department of Clinical Microbiology and Infectious Diseases. Haseki Training and Research Hospital, İstanbul.
authors.forename: G
authors.initials: G
authors.lastname: Unlü
authors.affiliation: Departments of Chest Diseases, Faculty of Medicine, University Kocaeli, Turkey.
authors.forename: T A
authors.initials: TA
authors.lastname: Onyılmaz
authors.affiliation: Departments of Chest Diseases, Faculty of Medicine, University Kocaeli, Turkey.
authors.forename: S A
authors.initials: SA
authors.lastname: Barış
authors.affiliation: Departments of Chest Diseases, Faculty of Medicine, University Kocaeli, Turkey.
authors.forename: N
authors.initials: N
authors.lastname: Turhan
authors.affiliation: Departments of Pathology, Faculty of Medicine, University Kocaeli, Turkey.
authors.forename: C
authors.initials: C
authors.lastname: Vural
authors.affiliation: Departments of Chest Diseases, Faculty of Medicine, University Kocaeli, Turkey.
authors.forename: I
authors.initials: I
authors.lastname: Başyiğit
authors.affiliation: Departments of Chest Diseases, Faculty of Medicine, University Kocaeli, Turkey.
authors.forename: H
authors.initials: H
authors.lastname: Boyacı
mesh_terms: D000368:Aged; D001706:Biopsy; D002637:Chest Pain / Q000209:etiology; D004417:Dyspnea / Q000209:etiology; D005260:Female; D005335:Fever of Unknown Origin / Q000175:diagnosis / Q000209:etiology*; D015769:Granuloma, Respiratory Tract / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D009336:Necrosis; D017565:Sarcoidosis, Pulmonary / Q000150:complications / Q000175:diagnosis*
keywords: dyspnea; fever of unknown origin; necrotizing sarcoid granulomatosis; vasculitis