title: Comparison of non-ablative and ablative fractional laser treatments in a postoperative scar study.
abstract: OBJECTIVE
  Postoperative scarring after thyroidectomy is a problem for both patients and clinicians. Recently, both non-ablative and ablative fractional laser (NFL and AFL) systems have attracted attention as potential therapies for the revision of thyroidectomy scars. The present split-scar study was designed to directly compare the efficacy of these two methods for the treatment of post-thyroidectomy scars.
  
  
  METHODS
  Twenty females (mean age 42.1 years, range 22-55) with scarring 2-3 months post-thyroidectomy were enrolled in the study. One half of the scar (chosen at random) was treated with NFL and the other half was treated with AFL. In each case, two treatments were given at 2-month intervals. Clinical photographs were taken at baseline, before each treatment, and at the final 3-month evaluation. Independent clinician grading of improvement and patient satisfaction were measured on a quartile scale. Color (erythema and melanin indices) and scar hardness were measured at baseline and at three months post-treatment with a dermaspectrometer and durometer, respectively.
  
  
  RESULTS
  The mean clinical improvement grades for AFL and NFL were highly similar, 2.45 ± 0.99 and 2.35 ± 0.85, respectively, without statistical significance (P = 0.752). However, NFL treatment resulted in statistically significant changes in erythema and pigmentation (P = 0.035 and P = 0.003, respectively), and skin hardness was significantly reduced after AFL treatment (P = 0.026).
  
  
  CONCLUSIONS
  Clinical improvement was not significantly different between the two systems; however, AFL was better at reducing scar hardness whereas NFL was superior for lightening color. These data suggest that a study assessing the feasibility of a combined approach for the revision of post-thyroidectomy scarring might be warranted.
authors.affiliation: Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Jung U
authors.initials: JU
authors.lastname: Shin
authors.forename: Dorjsuren
authors.initials: D
authors.lastname: Gantsetseg
authors.forename: Jin Young
authors.initials: JY
authors.lastname: Jung
authors.forename: Inhee
authors.initials: I
authors.lastname: Jung
authors.forename: Sungsik
authors.initials: S
authors.lastname: Shin
authors.forename: Ju Hee
authors.initials: JH
authors.lastname: Lee
mesh_terms: D000328:Adult; D002921:Cicatrix / Q000209:etiology* / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000295:instrumentation*; D054020:Lasers, Gas / Q000627:therapeutic use*; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D008875:Middle Aged; D017060:Patient Satisfaction; D013965:Thyroidectomy / Q000009:adverse effects*; D016896:Treatment Outcome; D055815:Young Adult
keywords: scarring; split-scar study; thyroidectomy