title: Sinobronchial allergic aspergillosis with allergic bronchopulmonary aspergillosis: a less common co-existence.
abstract: Allergic bronchopulmonary aspergillosis (ABPA) is an immunological pulmonary disorder that is characterised by a hyper-responsiveness of the airways to Aspergillus fumigatus. Although several other fungi may also present with similar clinical conditions, Aspergillus remains the most common fungal pathogen causing airway infections. Co-existence of ABPA with allergic Aspergillus sinusitis (AAS) is an uncommon presentation. The concept of one airway/one disease justifies the co-existence of ABPA with AAS, but it does not always hold true. We report a case of a 35-year-old woman who presented with symptoms suggestive of bronchial asthma. On further investigation, the radiological pattern showed fleeting shadows and CT scan showed central cystic bronchiectatic changes characteristic of ABPA. The nasal secretions were investigated for the presence of Aspergillus and were found to be positive. Hence a diagnosis of ABPA with AAS was established. The patient was treated with oral steroids and antifungal drugs.
authors.affiliation: Department of Pulmonary Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Rashmi
authors.initials: R
authors.lastname: Upadhyay
authors.affiliation: Department of Pulmonary Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Surya
authors.initials: S
authors.lastname: Kant
authors.affiliation: Department of Pulmonary Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Ved
authors.initials: V
authors.lastname: Prakash
authors.affiliation: Department of Pulmonary Medicine, CMC, Vellore, Tamil Nadu, India.
authors.forename: S
authors.initials: S
authors.lastname: Saheer
mesh_terms: D000328:Adult; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000150:complications*; D005260:Female; D006801:Humans; D012852:Sinusitis / Q000150:complications*