title: Synthesis and antimicrobial activity of new norbornyl system based oxadiazole thioglycosides and acyclic nucleoside analogs.
abstract: New sugar hydrazones linked to norbornyl ring system, their oxadiazole acyclic nucleoside analogs and the corresponding thioglycosides were synthesized. The synthesized compounds were tested for their antimicrobial activity and displayed different degrees of activities or inhibitory actions. Their oxadiazole acyclic nucleoside analogs and thioglycosides showed higher activities.
authors.forename: Ashraf M
authors.initials: AM
authors.lastname: Mohamed
authors.forename: Wael A
authors.initials: WA
authors.lastname: El-Sayed
authors.forename: Husam R M
authors.initials: HR
authors.lastname: Al-Qalawi
authors.forename: Mousa O
authors.initials: MO
authors.lastname: Germoush
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects / Q000254:growth & development; D008826:Microbial Sensitivity Tests; D009636:Norbornanes / Q000138:chemical synthesis* / Q000494:pharmacology*; D009705:Nucleosides / Q000138:chemical synthesis* / Q000494:pharmacology*; D010069:Oxadiazoles / Q000138:chemical synthesis* / Q000494:pharmacology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000254:growth & development; D013302:Streptomyces / Q000187:drug effects / Q000254:growth & development; D013865:Thioglycosides / Q000138:chemical synthesis* / Q000494:pharmacology*
chemical_list: D000890:Anti-Infective Agents; D009636:Norbornanes; D009705:Nucleosides; D010069:Oxadiazoles; D013865:Thioglycosides