title: Bioinspired direct access to benzofuroindolines by oxidative [3 + 2] annulation of phenols and indoles.
abstract: The straightforward entry to benzofuroindoline containing natural product-like scaffolds has been achieved by a challenging [3 + 2] oxidative coupling between phenols and indoles. The reaction proceeds by NIS-oxidation of the indole followed by the trapping of the resulting electrophilic intermediate by phenol.
authors.affiliation: Univ Paris Sud and CNRS, Institut de Chimie Moléculaire et des Matériaux d'Orsay (ICMMO) , UMR8182, Equipe Méthodologie - Synthèse & Molécules Thérapeutiques (MS&MT), Bat. 410, 91405, Orsay, France.
authors.forename: Natacha
authors.initials: N
authors.lastname: Denizot
authors.forename: Annie
authors.initials: A
authors.lastname: Pouilhès
authors.forename: Mélissa
authors.initials: M
authors.lastname: Cucca
authors.forename: Rodolphe
authors.initials: R
authors.lastname: Beaud
authors.forename: Régis
authors.initials: R
authors.lastname: Guillot
authors.forename: Cyrille
authors.initials: C
authors.lastname: Kouklovsky
authors.forename: Guillaume
authors.initials: G
authors.lastname: Vincent
mesh_terms: D001572:Benzofurans / Q000737:chemistry*; D002384:Catalysis; D007211:Indoles / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010636:Phenols / Q000737:chemistry*
chemical_list: D001572:Benzofurans; D007211:Indoles; D010636:Phenols; C030374:indole