title: Normal-weight obesity: implications for cardiovascular health.
abstract: We sought to review the epidemiological features and clinical implications of normal-weight obesity. The concept of normal-weight obesity has been recently reported as an important risk factor for cardiovascular disease, metabolic dysregulation, and poor functional outcomes. However, in clinical practice, normal-weight obesity is not commonly recognized. In this review, we examine the clinical significance and important epidemiological outcomes of normal-weight obesity and describe other variants of adiposity and adiposity-related metabolic status. The incorporation of measures of body fat content and distribution in the clinical setting could allow more accurate identification of adiposity-related long-term risk. This could in turn lead to early lifestyle changes and behavioral modifications that are essential to the treatment of obesity.
authors.affiliation: Division of Cardiovascular Disease and Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA, jean.nathalie@mayo.edu.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Jean
authors.forename: Virend K
authors.initials: VK
authors.lastname: Somers
authors.forename: Ondrej
authors.initials: O
authors.lastname: Sochor
authors.forename: Jose
authors.initials: J
authors.lastname: Medina-Inojosa
authors.forename: Ernesto M
authors.initials: EM
authors.lastname: Llano
authors.forename: Francisco
authors.initials: F
authors.lastname: Lopez-Jimenez
mesh_terms: D000328:Adult; D000368:Aged; D001823:Body Composition; D050218:Body Fat Distribution; D015992:Body Mass Index; D001835:Body Weight; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000453:epidemiology*; D015897:Comorbidity; D005260:Female; D006304:Health Status; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000145:classification* / Q000453:epidemiology* / Q000503:physiopathology; D012016:Reference Values; D018570:Risk Assessment