title: Significant association of serum H. pylori IgG antibody titer with kidney function in renal transplanted patients.
abstract: BACKGROUND
  There is a paucity of information about the Helicobacter pylori (H.Pylori) infection in kidney recipients.
  
  
  OBJECTIVE
  At this study, we sought to investigate the association of some demographic and biochemical indices of kidney transplant patients with serum H. pylori antibody value.
  
  
  METHODS
  A total of 72 patients were enrolled in this study.
  
  
  RESULTS
  The mean of serum H. pylori IgG antibody titer was 3 ±4.6 U/mL (median= 1 U/mL). A significant positive correlation between serum H. pylori IgG antibody level and creatinine clearance was seen (r = 0.26, P = 0.02).
  
  
  CONCLUSIONS
  The important finding of this study was the significant positive association of serum H. pylori IgG antibody titer with renal function in renal transplant patient. It means that with gradual loss of kidney function, the probability of H. pylori-infection is increased. Hence, H. pylori infection which is one of the most important and treatable factor leading to a peptic ulcer disease should be treated and eradicated before embarking for transplant.
authors.affiliation: Department of Internal Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran.
authors.forename: Hamid
authors.initials: H
authors.lastname: Nasri
authors.affiliation: Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Rafieian-Kopaei
keywords: Helicobacter pylori; Kidney transplant; Renal function