title: Lower urinary tract function in dementia with Lewy bodies (DLB).
abstract: OBJECTIVE
  Dementia with Lewy bodies (DLB) is the second most common degenerative cause of dementia, whereas lower urinary tract (LUT) function in DLB patients has not been fully delineated. We investigated LUT function in DLB by clinical-urodynamic observations.
  
  
  METHODS
  We examined 32 patients with DLB (23 men, 9 women; aged 59-86 [mean, 75.9] years; disease duration, 0.2-17 [3.3] years). All patients underwent an electromyography-cystometry, and 21 patients underwent the sphincter motor unit potential analysis.
  
  
  RESULTS
  Ninety-one percent of patients had LUT symptoms: nighttime frequency (>8 times), 84%, and urinary incontinence (>1 per week), 50%. Detrusor overactivity was revealed in 87.1%, whereas postvoid residual was minimal. Neurogenic changes were shown in 50%.
  
  
  CONCLUSIONS
  LUT dysfunction is a common feature in DLB, attributable not only to dementia and immobility, but also to central and peripheral types of somato-autonomic dysfunction.
authors.affiliation: Neurology, Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan.
authors.forename: Fuyuki
authors.initials: F
authors.lastname: Tateno
authors.forename: Ryuji
authors.initials: R
authors.lastname: Sakakibara
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Ogata
authors.forename: Masahiko
authors.initials: M
authors.lastname: Kishi
authors.forename: Yohei
authors.initials: Y
authors.lastname: Tsuyusaki
authors.forename: Osamu
authors.initials: O
authors.lastname: Takahashi
authors.forename: Megumi
authors.initials: M
authors.lastname: Sugiyama
authors.forename: Akihiko
authors.initials: A
authors.lastname: Tateno
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004576:Electromyography; D005260:Female; D006801:Humans; D020961:Lewy Body Disease / Q000150:complications*; D059411:Lower Urinary Tract Symptoms / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D001743:Urinary Bladder / Q000503:physiopathology; D014563:Urodynamics / Q000502:physiology
keywords: Parkinson's disease; autonomic failure; dementia with Lewy bodies; lower urinary tract dysfunction; sphincter motor unit potential