title: Cone precursor cells are the cell-of-origin in retinoblastoma.
abstract: RB loss in human cone precursor cells promotes proliferation and retinoblastoma formation.
mesh_terms: D006801:Humans; D017949:Retinal Cone Photoreceptor Cells / Q000378:metabolism*; D012175:Retinoblastoma / Q000378:metabolism*; D016160:Retinoblastoma Protein / Q000235:genetics*
chemical_list: D016160:Retinoblastoma Protein