title: A lithium-rich composite metal oxide used as a SALDI-MS matrix for the determination of small biomolecules.
abstract: A lithium-rich composite metal oxide was evaluated as a novel matrix for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-MS). The low background interference and lithium-rich feature made it a highly efficient matrix for the analysis of small molecules with high reproducibility, sensitivity and strong salt tolerance.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China. hwliu@pku.edu.cn.
authors.forename: Ze
authors.initials: Z
authors.lastname: Li
authors.forename: Yi-Wei
authors.initials: YW
authors.lastname: Zhang
authors.forename: Yue-Long
authors.initials: YL
authors.lastname: Xin
authors.forename: Yu
authors.initials: Y
authors.lastname: Bai
authors.forename: Heng-Hui
authors.initials: HH
authors.lastname: Zhou
authors.forename: Hu-Wei
authors.initials: HW
authors.lastname: Liu
mesh_terms: D002614:Chelating Agents / Q000737:chemistry; D019343:Citric Acid / Q000737:chemistry; D003505:Cyclodextrins / Q000032:analysis / Q000737:chemistry; D004492:Edetic Acid / Q000737:chemistry; D005907:Gliclazide / Q000032:analysis / Q000737:chemistry; D005913:Glipizide / Q000032:analysis / Q000737:chemistry; D008055:Lipids / Q000032:analysis / Q000737:chemistry; D008094:Lithium / Q000737:chemistry*; D009844:Oligosaccharides / Q000032:analysis / Q000737:chemistry; D010087:Oxides / Q000737:chemistry*; D010455:Peptides / Q000032:analysis / Q000737:chemistry; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D002614:Chelating Agents; D003505:Cyclodextrins; D008055:Lipids; D009844:Oligosaccharides; D010087:Oxides; D010455:Peptides; D019343:Citric Acid; D008094:Lithium; D004492:Edetic Acid; D005907:Gliclazide; D005913:Glipizide