title: Exercise-induced rhabdomyolysis.
abstract: Exercise-induced rhabdomyolysis, or exertional rhabdomyolysis (ER), is a clinical entity typically considered when someone presents with muscle stiffness, swelling, and pain out of proportion to the expected fatigue post exercise. The diagnosis is confirmed by myoglobinuria, and an elevated serum Creatinine Phosphokinase (CPK) level, usually 10 times the normal range. However, an elevation in CPK is seen in most forms of strenuous exercise, up to 20 times the upper normal range. Therefore, there is no definitive pathologic CPK cut-off. Fortunately the dreaded complication of acute renal failure is rare compared to other forms rhabdomyolysis. We review the risks, diagnosis, clinical course and treatment for exercise- induced rhabdomyolysis.
authors.affiliation: Clinical Assistant Professor of Medicine at the Alpert Medical School of Brown University.
authors.forename: George
authors.initials: G
authors.lastname: Lee
mesh_terms: D058186:Acute Kidney Injury / Q000628:therapy; D003402:Creatine Kinase / Q000097:blood; D015444:Exercise; D006801:Humans; D009212:Myoglobinuria / Q000652:urine; D012206:Rhabdomyolysis / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy*; D012307:Risk Factors
chemical_list: D003402:Creatine Kinase
keywords: CPK; acute renal failure; exertional rhabdomyolysis; myoglobinuria