title: Spontaneous wound dehiscence after penetrating keratoplasty.
abstract: Spontaneous wound separation may be developed even months after suture removal especially in the context of long-term corticosteroid therapy. A 68-year-old Caucasian woman presented to our cornea clinic with spontaneous wound dehiscence after her third penetrating keratoplasty (PKP) which was performed three years ago. An Ahmed glaucoma valve (New World Medical, Ranchos Cucamonga, CA) was inserted ten months after the third PKP, which successfully controlled intraocular pressure (IOP). At the examination, the last sutures were removed eight months ago and she was using flourometholone 0.1 % (Sina Darou, Tehran, Iran) with a dose of once a day. There was one quadrant of wound dehiscence from 8 to 11 òclock associated with anterior wound gape and severe corneal edema. Resuturing was performed for the patient. At the one month examination, the corneal edema was resolved and best corrected visual acuity was 20/200 mainly due to previous glaucomatous optic neuropathy. Caution about the prolonged use of corticosteroids is necessary. Topical immunosuppressives could be a promising choice in this field.
authors.affiliation: Department of Ophthalmology, Eye Research Center, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran 133432134, Iran.
authors.forename: Alireza
authors.initials: A
authors.lastname: Foroutan
authors.affiliation: Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran 1336616351, Iran.
authors.forename: Seyed Ali
authors.initials: SA
authors.lastname: Tabatabaei
authors.affiliation: Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran 1336616351, Iran.
authors.forename: Mahmoud Jabbarvand
authors.initials: MJ
authors.lastname: Behrouz
authors.affiliation: Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran 1336616351, Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Zarei
authors.affiliation: Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran 1336616351, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Soleimani
keywords: penetrating keratoplasty; review; spontaneous; wound dehiscence