title: Carbon-hydrogen to carbon-phosphorus transformations.
abstract: Literature published between 2008 and 2013 concerning the functionalization of carbon-hydrogen into carbon-phosphorus bonds is surveyed. The chapter is organized by reaction mechanism. The majority of methods still proceed via deprotonation of C-H into C-M (M=Li, Na, etc.) followed by reaction with a phosphorus electrophile P-X, where X is usually chlorine. A few examples of electrophilic aromatic substitution and related processes have also been reported, although this approach has not yet been developed significantly. Over the past 5 years a rapidly growing family of reactions includes transition metal "C-H activation" and formally related radical-based processes has been developed. The latter processes offer exciting prospects for the synthesis of organophosphorus compounds.
authors.affiliation: Department of Chemistry, Texas Christian University, TCU Box 298860, Fort Worth, TX, 76129, USA, j.montchamp@tcu.edu.
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Montchamp