title: [Development of paste-type food for experiments with mice onboard unmanned spacecrafts].
abstract: One of the crucial issues of handling animals in space flight is availability of food and water supply systems. However, water supply for animal experiments onboard unmanned spacecrafts is a particularly formidable problem. To maintain laboratory mice in space flight, a paste-type food was formulated on the basis of the standard extruded combined food for laboratory rodents (PK-120) with a 18.3% wet protein content and moisture raised to 68%. Food manufacturing technology for rodents reproduces essentially the one for quails that had shown good advantages in an experiment with adult birds aboard orbital complex Mir. The proposed food was tested with white laboratory mice (males and females) of mature 37-d age. According to the data of blood clinical analysis and visceral organs morphology investigations, feeding with the paste-type food without additional water over 21 days did not change the life weight of mice or food digestibility and availability. These biological test results gave go to feed mice in the Bion-M1 and synchronous ground experiments with the paste-type food.
authors.forename: E I
authors.initials: EI
authors.lastname: Mednikova
authors.forename: T S
authors.initials: TS
authors.lastname: Gur'eva
authors.forename: O A
authors.initials: OA
authors.lastname: Dadasheva
authors.forename: V N
authors.initials: VN
authors.lastname: Sychev
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Morozova
mesh_terms: D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D004063:Digestion / Q000502:physiology; D004435:Eating / Q000502:physiology; D018504:Ecological Systems, Closed; D005260:Female; D005509:Food Dispensers, Automatic; D005511:Food Handling; D008297:Male; D051379:Mice; D013026:Space Flight; D014893:Weightlessness