title: Oral phenytoin toxicity causing sinus arrest: a case report.
abstract: We present a case of sinus node arrest leading to symptomatic junctional bradycardia from oral phenytoin toxicity, which is a rare presentation. Our patient had no prior cardiac history and was on phenytoin therapy for seizure disorder. Although bradycardia is more commonly associated with intravenous phenytoin and there were few case reports of bradycardia with oral phenytoin reported, the literature is limited. In this case report, we also reviewed the pathophysiology of phenytoin-induced cardiac toxicity.
authors.affiliation: Department of Internal Medicine, Creighton University Medical Center, 601 N 30th Street, Omaha, NE 68131-0216, USA.
authors.forename: Ravi K
authors.initials: RK
authors.lastname: Thimmisetty
authors.affiliation: Division of Cardiology, University of Minnesota, Mayo Mail Code 508, 420 Delaware Street SE, Minneapolis, MN 55455, USA.
authors.forename: Janardhana Rao
authors.initials: JR
authors.lastname: Gorthi
authors.affiliation: Department of Internal Medicine, Creighton University Medical Center, 601 N 30th Street, Omaha, NE 68131-0216, USA.
authors.forename: Mahmoud
authors.identifier: 0000-0002-2639-6926
authors.initials: M
authors.lastname: Abu Hazeem