title: Recurrence in regional pulmonary lymph nodes after surgery for isolated pulmonary metastasis from hepatocellular carcinoma.
abstract: Hepatocellular carcinoma occasionally metastasizes to extrahepatic organs, rarely to the mediastinal lymph nodes. We present the case of a 64-year-old man who presented with nodules in the upper and right lower lobes of the lung 4 years after undergoing resection of a hepatocellular carcinoma. We performed wedge resection of both lesions. Pathological examination showed that the lesion in the right upper lobe was non-small cell lung cancer and that in the right lower lobe hepatocellular carcinoma. We accordingly performed right upper lobectomy with lymph node dissection. Nine months later, enlarged subcarinal and segmental lymph nodes were detected and mediastinal lymph node metastases from the hepatocellular carcinoma diagnosed by transbronchial needle aspiration.
authors.affiliation: Department of General Thoracic Surgery, Tokai University Hachioji Hospital, 1838 Ishikawa Hachioji, Tokyo, 192-0032, Japan. asuga@is.icc.u-tokai.ac.jp.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Suga
authors.affiliation: Department of General Thoracic Surgery, Tokai University Hachioji Hospital, 1838 Ishikawa Hachioji, Tokyo, 192-0032, Japan.
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Yamada
authors.affiliation: Department of General Thoracic Surgery, Tokai University Hachioji Hospital, 1838 Ishikawa Hachioji, Tokyo, 192-0032, Japan.
authors.forename: Haruka
authors.initials: H
authors.lastname: Takeichi
authors.affiliation: Department of General Thoracic Surgery, Tokai University Hachioji Hospital, 1838 Ishikawa Hachioji, Tokyo, 192-0032, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Masuda
authors.affiliation: Department of General Thoracic Surgery, Tokai University Hachioji Hospital, 1838 Ishikawa Hachioji, Tokyo, 192-0032, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Nakamura
authors.affiliation: Division of General Thoracic Surgery, Department of Surgery, Tokai University School of Medicine, Kanagawa, Japan.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Iwazaki
mesh_terms: D044963:Biopsy, Fine-Needle; D018196:Carcinoma, Adenosquamous / Q000473:pathology; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000556:secondary / Q000601:surgery; D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary / Q000601:surgery*; D008197:Lymph Node Excision / Q000379:methods; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D008482:Mediastinum / Q000473:pathology; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000601:surgery; D000072078:Positron Emission Tomography Computed Tomography
keywords: Extrahepatic metastasis; Hepatocellular carcinoma; Non-small cell lung cancer; Positron emission tomography/computed tomography; Transbronchial needle aspiration