title: Characterization of collagen in non-small cell lung carcinoma with second harmonic polarization microscopy.
abstract: Polarization second harmonic microscopy was used for collagen imaging in human non-small cell lung carcinoma and normal lung tissues ex vivo and revealed significant differences in the nonlinear susceptibility component ratio, demonstrating potential use in cancer diagnosis.
authors.affiliation: Department of Physics and Institute for Optical Sciences, University of Toronto, 60 Saint George Street, Toronto, ON M5S1A7, Canada ; Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, ON L5L1C6, Canada.
authors.forename: Ahmad
authors.initials: A
authors.lastname: Golaraei
authors.affiliation: Department of Physics and Institute for Optical Sciences, University of Toronto, 60 Saint George Street, Toronto, ON M5S1A7, Canada ; Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, ON L5L1C6, Canada.
authors.forename: Richard
authors.initials: R
authors.lastname: Cisek
authors.affiliation: Department of Physics and Institute for Optical Sciences, University of Toronto, 60 Saint George Street, Toronto, ON M5S1A7, Canada ; Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, ON L5L1C6, Canada.
authors.forename: Serguei
authors.initials: S
authors.lastname: Krouglov
authors.affiliation: Princess Margaret Cancer Centre, University Health Network, 610 University Ave, Toronto, ON M5G 2M9, Canada.
authors.forename: Roya
authors.initials: R
authors.lastname: Navab
authors.affiliation: Princess Margaret Cancer Centre, University Health Network, 610 University Ave, Toronto, ON M5G 2M9, Canada.
authors.forename: Carolyn
authors.initials: C
authors.lastname: Niu
authors.affiliation: Princess Margaret Cancer Centre, University Health Network, 610 University Ave, Toronto, ON M5G 2M9, Canada.
authors.forename: Shingo
authors.initials: S
authors.lastname: Sakashita
authors.affiliation: Toronto General Hospital, University Health Network, 200 Elizabeth St, 9N-957, Toronto, ON M5G2C4, Canada.
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yasufuku
authors.affiliation: Princess Margaret Cancer Centre, University Health Network, 610 University Ave, Toronto, ON M5G 2M9, Canada.
authors.forename: Ming-Sound
authors.initials: MS
authors.lastname: Tsao
authors.affiliation: Princess Margaret Cancer Centre, University Health Network, 610 University Ave, Toronto, ON M5G 2M9, Canada.
authors.forename: Brian C
authors.initials: BC
authors.lastname: Wilson
authors.affiliation: Department of Physics and Institute for Optical Sciences, University of Toronto, 60 Saint George Street, Toronto, ON M5S1A7, Canada ; Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, ON L5L1C6, Canada.
authors.forename: Virginijus
authors.initials: V
authors.lastname: Barzda
keywords: (180.0180) Microscopy; (180.4315) Nonlinear microscopy; (190.4160) Multiharmonic generation