title: Congenital primary cutaneous anaplastic large-cell lymphoma: a case report.
abstract: Primary cutaneous anaplastic large-cell lymphoma (C-ALCL) is the second most common type of primary cutaneous T-cell lymphoma. The median age of onset of C-ALCL is 60 years. Presented here is a case of congenital CD30-positive (CD30(+)) primary C-ALCL in a 10-day-old neonate who presented with a large erythematous indurative plaque in the right postauricular area. A systemic workup of the patient excluded other potential causes. The neonate was treated with wide excision, but chemotherapy or radiation therapy was not administered, as the patient's parents did not consent to such treatment. The patient has been monitored for 30 months after excision and there has been no disease recurrence. C-ALCL rarely occurs in children, and to the best of our knowledge, this is the first reported case of a neonate with congenital primary C-ALCL.
authors.affiliation: Departments of *Pathology, †Dermatology, and ‡Plastic and Reconstructive Surgery, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea; and §Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: An Na
authors.initials: AN
authors.lastname: Seo
authors.forename: Seok-Jong
authors.initials: SJ
authors.lastname: Lee
authors.forename: Yoon Hyuk
authors.initials: YH
authors.lastname: Choi
authors.forename: Ho Yun
authors.initials: HY
authors.lastname: Chung
authors.forename: Jooryung
authors.initials: J
authors.lastname: Huh
authors.forename: Ghil Suk
authors.initials: GS
authors.lastname: Yoon
mesh_terms: D000077548:Anaplastic Lymphoma Kinase; D014408:Biomarkers, Tumor / Q000032:analysis / Q000235:genetics; D001706:Biopsy; D006801:Humans; D007150:Immunohistochemistry; D017404:In Situ Hybridization, Fluorescence; D007231:Infant, Newborn; D017730:Ki-1 Antigen / Q000032:analysis; D054446:Lymphoma, Primary Cutaneous Anaplastic Large Cell / Q000151:congenital* / Q000276:immunology / Q000473:pathology / Q000601:surgery; D020794:Receptor Protein-Tyrosine Kinases / Q000235:genetics; D012878:Skin Neoplasms / Q000151:congenital* / Q000276:immunology / Q000473:pathology / Q000601:surgery; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor; D017730:Ki-1 Antigen; D000077548:Anaplastic Lymphoma Kinase; D020794:Receptor Protein-Tyrosine Kinases