title: Case study to illustrate an approach for detecting contamination and impurities in pesticide formulations.
abstract: Counterfeit pesticides threaten public health, food trade, and the environment. The present work draws attention to the importance of regular monitoring of impurities in formulated pesticide products. General screening revealed the presence of carbaryl as a contaminant in a copper oxychloride formulated product. In this paper, as a case study, a liquid chromatographic diode array-mass spectrometric method developed for general screening of pesticide products and quantitative determination of carbaryl together with its validation is presented. The proposed testing strategy is considered suitable for use as a general approach for testing organic contaminants and impurities in solid pesticide formulations.
authors.affiliation: Laboratory of Chemical Control of Pesticides and ‡Laboratory of Pesticides Toxicology, Department of Pesticides Control and Phytopharmacy, Benaki Phytopathological Institute , 8 St. Delta Street, Kifissia, 14561 Athens, Greece.
authors.forename: Helen
authors.initials: H
authors.lastname: Karasali
authors.forename: Konstantinos M
authors.initials: KM
authors.lastname: Kasiotis
authors.forename: Kyriaki
authors.initials: K
authors.lastname: Machera
authors.forename: Arpad
authors.initials: A
authors.lastname: Ambrus
mesh_terms: D012721:Carbaryl / Q000032:analysis; D002851:Chromatography, High Pressure Liquid; D008401:Gas Chromatography-Mass Spectrometry; D010573:Pesticide Residues / Q000032:analysis*; D010575:Pesticides / Q000032:analysis*; D015203:Reproducibility of Results; D018570:Risk Assessment
chemical_list: D010573:Pesticide Residues; D010575:Pesticides; D012721:Carbaryl
keywords: HPLC; LC-MS; carbaryl; copper oxychloride; counterfeit; impurities; monitoring; pesticides; quality control