title: Motor preparation attenuates neural variability and beta-band LFP in parietal cortex.
abstract: Accumulative evidence shows that neural variability is meaningful and powerful during brain information processing, but how cognitive state influences neural variability is still unclear. We studied neural variability during motor preparation in lateral intraparietal area (LIP), a brain area closely involved in saccade generation. During motor preparation, we observed significant variability decline, and the decline highly correlated with beta-band local field potential (LFP) fluctuations. Furthermore, we found similar variance-LFP correlations in both the memory-guided saccade task and the visually-guided saccade task. These results indicate a possible linkage between beta-band LFP and trial-to-trial neural variability.
authors.affiliation: 1] Jiangsu Province Key Laboratory of Anesthesiology and Jiangsu Province Key Laboratory of Anesthesia and Analgesia Application Technology, Xuzhou Medical College, Xuzhou, China, 221004 [2] Institute of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, and University of Chinese Academy of Sciences, Shanghai, China, 200031.
authors.forename: Mo
authors.initials: M
authors.lastname: Chen
authors.affiliation: Department of Physiology and Neurobiology, Xinxiang Medical University, Xinxiang, China, 453003.
authors.forename: Linyu
authors.initials: L
authors.lastname: Wei
authors.affiliation: 1] Jiangsu Province Key Laboratory of Anesthesiology and Jiangsu Province Key Laboratory of Anesthesia and Analgesia Application Technology, Xuzhou Medical College, Xuzhou, China, 221004 [2] Institute of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, and University of Chinese Academy of Sciences, Shanghai, China, 200031.
authors.forename: Yu
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000818:Animals; D008253:Macaca mulatta / Q000502:physiology; D008568:Memory / Q000502:physiology*; D008606:Mental Processes / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D010296:Parietal Lobe / Q000502:physiology*