title: Determination of the absolute configuration of two pairs of C-8 - C-9' linked neolignan enantiomers.
abstract: Two pairs of new neolignan enantiomers, (±)-torreyayunan A (1a/1b) and (±)-torreyayunan B (2a/2b), featuring a rare C-8 - C-9' linked skeleton, were isolated from leaves and twigs of Torreya yunnanensis. Their absolute configuration involving two chiral centers was determined by combined spectral and Density Functional Theory (DFT) calculation. This is the first report of the absolute configuration of this group of neolignans.
authors.affiliation: School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China.
authors.forename: Jing-Mei
authors.initials: JM
authors.lastname: Bao
authors.forename: Zhong-Bin
authors.initials: ZB
authors.lastname: Cheng
authors.forename: Jun-Sheng
authors.initials: JS
authors.lastname: Zhang
authors.forename: Jian-Yong
authors.initials: JY
authors.lastname: Zhu
authors.forename: Gui-Hua
authors.initials: GH
authors.lastname: Tang
authors.forename: Li-She
authors.initials: LS
authors.lastname: Gan
authors.forename: Sheng
authors.initials: S
authors.lastname: Yin
mesh_terms: D002942:Circular Dichroism; D017705:Lignans / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry; D013237:Stereoisomerism; D032490:Taxaceae / Q000737:chemistry
chemical_list: D017705:Lignans; C000599985:torreyayunan A
keywords: C-8 − C-9′ linked skeleton; DFT; ECD; Torreya yunnanensis; absolute configuration; neolignan enantiomers