title: Phenolic glycosides from Glycosmis pentaphylla.
abstract: Three new phenolic glycosides, named as glycopentosides A-C (1-3), along with nine known compounds were isolated from the n-BuOH extract of stems of Glycosmis pentaphylla. Their structures were determined by using spectroscopic and chemical methods. Bioassay showed that compound 10 (tachioside) could inhibit nitric oxide production in lipopolysaccharides-stimulated RAW 264.7 cells with IC50 value of 12.14 μM.
authors.affiliation: a College of Chemistry and Materials Science, South Central University for Nationalities , Wuhan 430074 , China.
authors.forename: Er-Li
authors.initials: EL
authors.lastname: Tian
authors.forename: Yuan-Yuan
authors.initials: YY
authors.lastname: Cui
authors.forename: Guang-Zhong
authors.initials: GZ
authors.lastname: Yang
authors.forename: Zhi-Nan
authors.initials: ZN
authors.lastname: Mei
authors.forename: Yu
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D008070:Lipopolysaccharides / Q000494:pharmacology; D051379:Mice; D015394:Molecular Structure; D009569:Nitric Oxide / Q000096:biosynthesis; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018547:Plant Stems / Q000737:chemistry; D027821:Rutaceae / Q000737:chemistry*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D004365:Drugs, Chinese Herbal; D006027:Glycosides; D008070:Lipopolysaccharides; D010636:Phenols; C000595814:glycopentoside A; C000595815:glycopentoside B; C000595816:glycopentoside C; D009569:Nitric Oxide
keywords: Glycosmis pentaphylla; Rutaceae; nitric oxide production; phenolic glycosides