title: Genital tract microbial isolate in women with preterm pre-labour rupture of membranes in resource-constrained community setting.
abstract: This study determined patterns of microbial isolates in genital tract of women with preterm pre-labour rupture of membranes (PPROM) compared with cases without PPROM. Endocervical swabs of women with confirmed diagnosis of PPROM were examined microbiologically and compared in blinded pattern with gestational-age-matched controls. One hundred and five microbiological results each for cases and controls were analysed. Positive microbial cultures were seen in 79.05% of cases versus 6.67% of controls. Streptococcus spp. (31.43%) was the commonest organism isolated in cases (p < 0.001), while Candida albicans was significantly more in controls (p < 0.001). The highest incidence of PPROM (82.86%) occurred in gestational ages of 28-30 and 34-36 weeks. No fewer than 75.24% cases occurred in low parity (0-2). Majority occurred in extremes of viable preterm gestation and in women of low parity.
authors.affiliation: a Department of Obstetrics and Gynecology , Nnamdi Azikiwe University, Teaching Hospital , Nnewi , Nigeria.
authors.forename: G U
authors.initials: GU
authors.lastname: Eleje
authors.affiliation: a Department of Obstetrics and Gynecology , Nnamdi Azikiwe University, Teaching Hospital , Nnewi , Nigeria.
authors.forename: J I
authors.initials: JI
authors.lastname: Adinma
authors.affiliation: b Department of Radiography , Nnamdi Azikiwe University , Nnewi , Nigeria.
authors.forename: D C
authors.initials: DC
authors.lastname: Ugwuanyi
authors.affiliation: a Department of Obstetrics and Gynecology , Nnamdi Azikiwe University, Teaching Hospital , Nnewi , Nigeria.
authors.forename: J I
authors.initials: JI
authors.lastname: Ikechebelu
authors.affiliation: a Department of Obstetrics and Gynecology , Nnamdi Azikiwe University, Teaching Hospital , Nnewi , Nigeria.
authors.forename: C I
authors.initials: CI
authors.lastname: Okafor
authors.affiliation: a Department of Obstetrics and Gynecology , Nnamdi Azikiwe University, Teaching Hospital , Nnewi , Nigeria.
authors.forename: C O
authors.initials: CO
authors.lastname: Ezeama
authors.affiliation: c Department of Parasitology and Entomology , Nnamdi Azikiwe University , Awka , Nigeria.
authors.forename: C N
authors.initials: CN
authors.lastname: Ogbuagu
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000382:microbiology*; D005836:Genitalia, Female / Q000382:microbiology*; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy; D014626:Vaginal Smears; D055815:Young Adult
keywords: Controls; PPROM; endocervical swabs; microbial agents; positive cultures