title: A synchronous pancreatic neuroendocrine tumor and duodenal gastrointestinal stromal tumor.
abstract: We recently encountered the case of a patient with a synchronous duodenal gastrointestinal stromal tumor (GIST) and pancreatic neuroendocrine tumor (PNET). This is the first report of this specific combination of multiple primary tumors, although three cases involving both PNET and gastric GIST have previously been reported. Since the duodenal GIST developed close to the pancreatic uncus in this case, we considered the possibility of multiple PNETs in the differential diagnosis. However, a histopathological examination using endoscopic ultrasonography-guided fine-needle aspiration confirmed the diagnosis of multiple primary lesions, involving PNET and duodenal GIST.
authors.affiliation: Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Japan.
authors.forename: Keijiro
authors.initials: K
authors.lastname: Ueda
authors.forename: Masayuki
authors.initials: M
authors.lastname: Hijioka
authors.forename: Lingaku
authors.initials: L
authors.lastname: Lee
authors.forename: Hisato
authors.initials: H
authors.lastname: Igarashi
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Niina
authors.forename: Takashi
authors.initials: T
authors.lastname: Osoegawa
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Nakamura
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Takahashi
authors.forename: Shinichi
authors.initials: S
authors.lastname: Aishima
authors.forename: Takao
authors.initials: T
authors.lastname: Ohtsuka
authors.forename: Ryoichi
authors.initials: R
authors.lastname: Takayanagi
authors.forename: Tetsuhide
authors.initials: T
authors.lastname: Ito
mesh_terms: D000368:Aged; D044963:Biopsy, Fine-Needle; D004379:Duodenal Neoplasms / Q000175:diagnosis*; D019160:Endosonography; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis*; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D018358:Neuroendocrine Tumors / Q000175:diagnosis*; D010190:Pancreatic Neoplasms / Q000175:diagnosis*