title: Macular retinal detachment associated with intrachoroidal cavitation in myopic patients.
abstract: OBJECTIVE
  To investigate the clinical characteristics and treatment outcomes of macular retinal detachment (MRD) associated with intrachoroidal cavitation (ICC) in myopic patients.
  
  
  METHODS
  In this retrospective, consecutive, interventional case series, five patients with ICC and associated MRD were enrolled from January 2005 to December 2012. Basic ocular characteristics and clinical appearances of their ICC and MRD were recorded. Individual treatment courses were assessed with fundus photographs and serial optical coherence tomography.
  
  
  RESULTS
  The average age and refraction were 43.8 ± 11.0 years old and -9.37 ± 2.73 diopters, respectively. Initial BCVA ranged from 20/100 to 20/30. Definite communication between the ICC and the subretinal space was noted in one case, suspected curvilinear communication in two cases, and between the peripapillary area and the subretinal space in two cases. Two cases received intravitreal injection of perfluoropropane and peripapillary laser; subretinal fluid (SRF) resolved in one and decreased in the other. One case had SRF reabsorbed after prolonged use of topical carbonic anhydrase inhibitor.
  
  
  CONCLUSIONS
  ICC in high myopic patients may be associated with MRD. There might be communication between the ICC and the subretinal space. Intravitreal injection of an expansile gas may be beneficial, but the best treatment remains undetermined.
authors.affiliation: Department of Ophthalmology, National Taiwan University Hospital, No. 7, Chung Shan South Road, Taipei, Taiwan.
authors.forename: Ta-Ching
authors.initials: TC
authors.lastname: Chen
authors.forename: Chang-Hao
authors.initials: CH
authors.lastname: Yang
authors.forename: Jen-Pin
authors.initials: JP
authors.lastname: Sun
authors.forename: Muh-Shy
authors.initials: MS
authors.lastname: Chen
authors.forename: Chung-May
authors.initials: CM
authors.lastname: Yang
mesh_terms: D000328:Adult; D015862:Choroid Diseases / Q000175:diagnosis / Q000209:etiology*; D058450:Endotamponade; D005260:Female; D005451:Fluorescein Angiography; D005466:Fluorocarbons / Q000008:administration & dosage; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000150:complications*; D016684:Prone Position; D012029:Refraction, Ocular / Q000502:physiology; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012189:Retrospective Studies; D058471:Subretinal Fluid; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology
chemical_list: D005466:Fluorocarbons; C042852:perflutren