title: Synchronous gallbladder and pancreatic cancer associated with pancreaticobiliary maljunction.
abstract: We report the case of a 46-year-old woman who presented with chronic intermittent abdominal pain without jaundice; abdominal ultrasonography showed thickening of the gallbladder wall and dilatation of the bile duct. Endoscopic retrograde cholangiopancreaticography showed pancreatobiliary maljunction with proximal common bile duct dilatation. Pancreatobiliary maljunction was diagnosed. A computed tomography scan of the abdomen showed suspected gallbladder cancer and distal common bile duct obstruction. A pancreatic head mass was incidentally found intraoperative. Radical cholecystectomy with pancreatoduodenectomy was performed. The pathological report showed gallbladder cancer that was synchronous with pancreatic head cancer. In the pancreatobiliary maljunction with pancreatobiliary reflux condition, double primary cancer of the pancreatobiliary system should be awared.
authors.affiliation: Narongsak Rungsakulkij, Department of Surgery, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
authors.forename: Narongsak
authors.initials: N
authors.lastname: Rungsakulkij
authors.affiliation: Narongsak Rungsakulkij, Department of Surgery, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
authors.forename: Paisarn
authors.initials: P
authors.lastname: Boonsakan
mesh_terms: D001652:Bile Ducts / Q000002:abnormalities* / Q000000981:diagnostic imaging; D001706:Biopsy; D002760:Cholangiopancreatography, Endoscopic Retrograde; D002763:Cholecystectomy; D005260:Female; D005706:Gallbladder Neoplasms / Q000473:pathology* / Q000601:surgery; D006801:Humans; D033162:Incidental Findings; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000601:surgery; D010179:Pancreas / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000601:surgery; D010190:Pancreatic Neoplasms / Q000473:pathology* / Q000601:surgery; D016577:Pancreaticoduodenectomy; D011237:Predictive Value of Tests; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D018615:Ultrasonography, Doppler, Color
keywords: Endoscopic retrograde cholangiopancreaticography; Gallbladder cancer; Pancreatic cancer; Pancreaticobiliary maljunction