title: [Hereditary palmoplantar keratoderma - a focus on clinical and molecular genetic aspects].
abstract: Hereditary palmoplantar keratoderma comprises a heterogenous group of genodermatoses. The clinical spectrum of palmoplantar keratoderma can range from pure skin thickening, restricted to palmoplantar skin to complex conditions with dental anomalies, eye symptoms, deafness, cardiac disease and cancer. The classification of hereditary palmoplantar keratoderma has been complicated. In recent years the molecular genetic background has been clarified for an increasing number of palmoplantar keratodermas, which makes it possible to make a more accurate diagnosis.
authors.affiliation: Klinisk Genetisk Afdeling, Aalborg Universitetshospital, Ladegårdsgade 5, 9000 Aalborg. shailajah@hotmail.com.
authors.forename: Shailajah
authors.initials: S
authors.lastname: Kamaleswaran
authors.forename: Lilian Bomme
authors.initials: LB
authors.lastname: Ousager
authors.forename: Rasmus Overgaard
authors.initials: RO
authors.lastname: Bach
authors.forename: Anette
authors.initials: A
authors.lastname: Bygum
mesh_terms: D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000175:diagnosis / Q000235:genetics / Q000473:pathology