title: Symptoms of an intrauterine hematoma associated with pregnancy complications: a systematic review.
abstract: OBJECTIVE
  To evaluate the predictive value of the symptoms of an intrauterine hematoma (IUH) for adverse pregnancy outcomes.
  
  
  METHODS
  A literature review was performed with the search terms, including intrauterine/subchorionic/retroplacental/subplacental hematoma/hemorrhage/bleeding/collection/fluid, covering the period from January, 1981 to January, 2014. We just focused on the pregnancy outcomes associated with different symptoms of an IUH.
  
  
  RESULTS
  It is generally agreed that a retroplacental, posterior or subchorionic in the fundus of uterus, and/or persistent IUH is associated with adverse outcomes in the ongoing pregnancy. However, the prognosis value of both volume and gestational age at diagnosis of IUH still remains controversial. Some researchers argue that a large IUH is associated with an increased risk of adverse events during pregnancy while others refuted. It is believed by some that the earlier an IUH was detected, the higher the risk for adverse outcomes would be, while no or weak association were reported by other studies. The prognostic value of the simultaneous presence of vaginal bleeding on pregnancy outcome is also controversial.
  
  
  CONCLUSIONS
  Both the position relative to the placenta or uterus and duration of IUH have strong predictive value on the prognosis in the ongoing pregnancy. However, the prognostic values of the IUH volume, gestational age at diagnosis and the simultaneous presence of vaginal bleeding remain controversial up to now. Moreover, most of previous reports are small, uncontrolled studies with incomplete information. Prospective, large sample, cohorts studies which take all detailed symptoms of an IUH into consideration are needed when we evaluate its clinical significance in the prognosis of pregnancy.
authors.affiliation: Reproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
authors.forename: Lan
authors.initials: L
authors.lastname: Xiang
authors.affiliation: Reproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
authors.forename: Zhaolian
authors.initials: Z
authors.lastname: Wei
authors.affiliation: Reproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
authors.forename: Yunxia
authors.initials: Y
authors.lastname: Cao
mesh_terms: D005260:Female; D006406:Hematoma / Q000209:etiology* / Q000473:pathology*; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000473:pathology*; D011256:Pregnancy Outcome; D014592:Uterine Hemorrhage / Q000209:etiology* / Q000473:pathology*; D014599:Uterus / Q000098:blood supply / Q000473:pathology*