title: Quality control evaluation of Keshamasi, Keshanjana and Keshamasi eye ointment.
abstract: BACKGROUND
  Keshanjana (collyrium) is a well known Ayurvedic preparation prepared out of Keshamasi (ash prepared by scalp hairs) mixed with Goghrita (cow's ghee). This medicine is indicated for the treatment of Shushkakshipaka (dry eye syndrome) in the classical literature of Ayurveda; hence, it was under taken for standardization and clinical evaluation in an extra-mural research project from Central Council for Research in Ayurvedic Sciences, Department of AYUSH, New Delhi.
  
  
  OBJECTIVE
  To develop standard quality parameters for the Keshamasi, Keshanjana and Keshamasi ointment.
  
  
  METHODS
  Scalp hairs of male and females collected from saloons were converted to classical Masi Kalpana and mixed with cow ghee and petrolatum in the ratio of 1:5 to prepare the Keshanjana and Keshamasi ointment respectively. Standard Operation Procedure (SOP) were adopted and recorded accordingly. The raw material, furnished products and plain Goghrita were subjected for quality control parameters i.e., physico-chemical evaluation, anti-microbial study, particle size analysis, heavy metal analysis through inductive couple plasma spectroscopy with high performance thin layer liquid chromatography fingerprints.
  
  
  RESULTS
  Rancidity was negative in all the samples, indicating that the physico-chemical parameters are in acceptable range. Lead and zinc were present in most of the samples; while all samples are were free from microbial contamination.
  
  
  CONCLUSIONS
  As no standards are available to compare the results of the current study, the observations cannot be compared. Thus the profile generated in the current study can be considered as standard to refer in future studies.
authors.affiliation: Department of Shalakya Tantra, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India.
authors.forename: Kartar Singh
authors.initials: KS
authors.lastname: Dhiman
authors.affiliation: Pharmaceutical Chemistry Laboratory, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India.
authors.forename: Vinay J
authors.initials: VJ
authors.lastname: Shukla
authors.affiliation: Analytical Development Laboratory, Zydus-Cadila, Ahmedabad, Gujarat, India.
authors.forename: Nayan R
authors.initials: NR
authors.lastname: Bhalodia
authors.affiliation: Marketing and Business Development, eVaidyaJi Wellness Pvt. Ltd., Jaipur, Rajashtan, India.
authors.forename: Vinay R
authors.initials: VR
authors.lastname: Sharma
keywords: Keshamasi; Keshanjana; ointment; quality control profile