title: Dual resonance approach to decoupling surface and bulk attributes in photonic crystal biosensor.
abstract: A sub-wavelength grating-based photonic crystal sensor is designed to excite two spectrally and spatially different guided mode resonances that have distinctive electric field distributions. We present and validate the uni-polarized dual resonance approach to separating bulk index perturbations from surface-binding events in a single measurement by monitoring the resonance wavelength shifts. This self-referencing method will reduce errors in the measurement of biomolecule binding events on sensor surfaces in a perturbed environmental background.
authors.forename: Md Nazmul
authors.initials: MN
authors.lastname: Hossain
authors.forename: John
authors.initials: J
authors.lastname: Justice
authors.forename: Pierre
authors.initials: P
authors.lastname: Lovera
authors.forename: Alan
authors.initials: A
authors.lastname: O'Riordan
authors.forename: Brian
authors.initials: B
authors.lastname: Corbett
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D055620:Optical Phenomena; D017785:Photons; D013499:Surface Properties