title: Preparation and pharmaceutical evaluation of nicotinamide stick for eradication of Staphylococcus epidermidis.
abstract: BACKGROUND
  Staphylococcus epidermidis is a part of the skin's normal flora that can cause acne. This study was designed to evaluate the efficacy of nicotinamide as a stick in eradication of staphylococcus.
  
  
  METHODS
  For evaluating of Anti-microbial effect on S. epidermidis used well plate method. We chose five plates for nicotinamide and five for mupirocin. The zones of inhibition were measured and compared.
  
  
  RESULTS
  The results showed nicotinamide stick had anti-microbial effects, but in comparison to mupirocin it was significantly less (P = 0.003).
  
  
  CONCLUSIONS
  Nicotinamide stick was made and evaluated. This study showed that nicotinamide had anti-microbial effect on staphylococcus.
authors.affiliation: Department of Pharmaceutics, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Mohammad Ali
authors.initials: MA
authors.lastname: Shahtalebi
authors.affiliation: Department of Pharmaceutics, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Rahim
authors.initials: R
authors.lastname: Bahrinajafi
authors.affiliation: Department of Pharmaceutics, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Sima
authors.initials: S
authors.lastname: Nahavandi
keywords: Medicated sticks; Staphylococcus epidermidis; nicotinamide