title: A new α-pyrone metabolite from a mangrove plant endophytic fungus, Fusarium sp.
abstract: A new α-pyrone derivative, compound 2, and a known one, cladobotrin V, were isolated from the culture broth of the mangrove endophyte Fusarium sp. IM-37. Their structures were determined spectroscopically and compared with previously reported spectral data. Compound 2 restored the growth inhibition caused by hyperactivated Ca(2+)-signaling in mutant yeast.
authors.affiliation: a Department of Bioresource Engineering , Faculty of Agriculture, Yamagata University , Tsuruoka , Yamagata 997-8555 , Japan.
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Shiono
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Shibuya
authors.forename: Takuya
authors.initials: T
authors.lastname: Koseki
authors.lastname: Harizon
authors.forename: Unang
authors.initials: U
authors.lastname: Supratman
authors.forename: Shota
authors.initials: S
authors.lastname: Uesugi
authors.forename: Ken-Ichi
authors.initials: K
authors.lastname: Kimura
mesh_terms: D005670:Fusarium / Q000737:chemistry*; D007214:Indonesia; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011753:Pyrones / Q000737:chemistry / Q000302:isolation & purification*; D043982:Rhizophoraceae / Q000382:microbiology; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000235:genetics
chemical_list: D011753:Pyrones; C000598798:cladobotrin V
keywords: Ca2+-signaling; Fusarium sp; cladobotrin V; endophyte; mangrove