title: Patterned electrospun nanofiber matrices via localized dissolution: potential for guided tissue formation.
abstract: With the assistance of an ink-jet printer, solvent (the "ink") can be controllably and reproducibly printed onto electrospun nanofiber meshes (the "paper") to generate various micropatterns and subsequently guide distinct cellular organization and phenotype expression. In combination with the nanofiber-assisted layer-by-layer cell assembly, the patterned electrospun meshes will define an instructive microenvironment for guided tissue formation.
authors.affiliation: Chemistry, Chemical Biology and Biomedical Engineering, Stevens Institute of Technology, 1 Castle Point on Hudson, Hoboken, NJ, 07030, USA.
authors.forename: Chao
authors.initials: C
authors.lastname: Jia
authors.forename: Dou
authors.initials: D
authors.lastname: Yu
authors.forename: Marven
authors.initials: M
authors.lastname: Lamarre
authors.forename: Philip L
authors.initials: PL
authors.lastname: Leopold
authors.forename: Yang D
authors.initials: YD
authors.lastname: Teng
authors.forename: Hongjun
authors.initials: H
authors.lastname: Wang
mesh_terms: D003094:Collagen / Q000737:chemistry / Q000378:metabolism; D017076:Computer-Aided Design; D016650:Fluorescein-5-isothiocyanate / Q000031:analogs & derivatives / Q000737:chemistry; D057139:Nanofibers / Q000737:chemistry*; D011091:Polyesters / Q000737:chemistry; D012710:Serum Albumin, Bovine / Q000737:chemistry
chemical_list: D011091:Polyesters; C039217:fluorescein isothiocyanate bovine serum albumin; C016240:polycaprolactone; D012710:Serum Albumin, Bovine; D003094:Collagen; D016650:Fluorescein-5-isothiocyanate
keywords: electrospinning; guided tissue formation; localized nanofiber dissolution; micropatterns