title: Nucleosomes, transcription, and probability.
abstract: Speaking of current measurements on single ion channel molecules, David Colquhoun wrote in 2006, "Individual molecules behave randomly, so suddenly we had to learn how to deal with stochastic processes." Here I describe theoretical efforts to understand recent experimental observations on the chromatin structure of single gene molecules, a molecular biologist's path toward probabilistic theories.
authors.affiliation: Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064.
authors.forename: Hinrich
authors.initials: H
authors.lastname: Boeger
mesh_terms: D000135:Acid Phosphatase / Q000235:genetics / Q000378:metabolism; D000818:Animals; D003198:Computer Simulation; D008390:Markov Chains; D008954:Models, Biological; D015233:Models, Statistical; D009707:Nucleosomes / Q000737:chemistry / Q000378:metabolism*; D011401:Promoter Regions, Genetic; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics / Q000378:metabolism; D014158:Transcription, Genetic
chemical_list: D009707:Nucleosomes; D029701:Saccharomyces cerevisiae Proteins; D000135:Acid Phosphatase; C488916:PHO5 protein, S cerevisiae