title: Nickel(0)-catalyzed [2 + 2 + 1] carbonylative cycloaddition of imines and alkynes or norbornene leading to γ-lactams.
abstract: The first nickel(0)-catalyzed [2 + 2 + 1] carbonylative cycloaddition reaction of imines and alkynes or norbornene has been achieved by employing phenyl formate as a CO source. With this method, a variety of N-benzenesulfonyl, -tosyl, and -phosphoryl-substituted γ-lactams can be prepared in good to high yields.
authors.affiliation: Department of Applied Chemistry, Faculty of Engineering, Osaka University , Suita, Osaka 565-0871, Japan.
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Hoshimoto
authors.forename: Tomoya
authors.initials: T
authors.lastname: Ohata
authors.forename: Yukari
authors.initials: Y
authors.lastname: Sasaoka
authors.forename: Masato
authors.initials: M
authors.lastname: Ohashi
authors.forename: Sensuke
authors.initials: S
authors.lastname: Ogoshi
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D061565:Cycloaddition Reaction; D007097:Imines / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D009532:Nickel / Q000737:chemistry*; D009636:Norbornanes / Q000737:chemistry*
chemical_list: D000480:Alkynes; D007097:Imines; D009636:Norbornanes; C046060:2-norbornene; D009532:Nickel