title: The role of a novel digital microcapillary instrument in detecting blood and plasma hyperviscosity.
abstract: OBJECTIVE
  to test the precision and accuracy of a Digital Microcapillary instrument in measuring blood and plasma viscosity.
  
  
  METHODS
  about 40 blood samples were drawn for precision test. The samples were obtained from patients admitted for Medical Check-Up at CiptoMangunkusumo Hospital (RSCM) in December 2011.Accuracy test was evaluated using cross-sectional design and involving 135 patients with acute ischemic stroke. The patients underwent either inpatients or outpatients care at Department of Clinical Pathology, Department of Neurology,and Emergency Unit of RSCM, Fatmawati Hospital Jakarta, Prikasih Hospital Jakarta, and Bhakti Yuda Hospital Depok. The precision test was evaluated by calculating the coefficient of variation (CV), interrater variability of Cronbach Alpha, and reliability coefficient of Bland Altman. The accuracy of the test was evaluated with a diagnostic test. The gold standard used for these tests was Brookfield LV-DV III viscometer.
  
  
  RESULTS
  the results of precision test were: CV = 0.04; interrater variability of blood and plasma viscosity = 0.94 and 0.82, respectively; the Bland Altman mean difference = -0.19. The results of accuracy test were: sensitivity of blood and plasma viscosity measurement were 88.9% and 100%, respectively; specificity of blood and plasma viscosity measurement were 88.9% and 84%, respectively.
  
  
  CONCLUSIONS
  the digital microcapillary has high sensitivity and specificity; therefore the instrument can be considered to be used as screening test tool to measure blood and plasma viscosity.
authors.affiliation: Department of Neurology, Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
authors.forename: Al
authors.initials: A
authors.lastname: Rasyid
authors.forename: Jusuf
authors.initials: J
authors.lastname: Misbach
authors.forename: Jan S
authors.initials: JS
authors.lastname: Purba
authors.forename: Ina S
authors.initials: IS
authors.lastname: Timan
authors.forename: Lugyanti
authors.initials: L
authors.lastname: Sukrisman
authors.forename: Muchtaruddin
authors.initials: M
authors.lastname: Mansyur
authors.forename: Efta
authors.initials: E
authors.lastname: Yudiarsah
authors.lastname: Suroto
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001809:Blood Viscosity; D003430:Cross-Sectional Studies; D005260:Female; D006403:Hematologic Tests / Q000295:instrumentation*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D010949:Plasma / Q000502:physiology; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D020521:Stroke / Q000097:blood / Q000175:diagnosis*; D055815:Young Adult