title: [Preparation and quality evaluation of microcapsules of volatile oil from Ledum palustre].
abstract: OBJECTIVE
  To study the preparation of microcapsules of volatile oil from Ledum palustre and its quality evaluation.
  
  
  METHODS
  The microcapsules were prepared by complex coacervation with encapsulation efficiency as evaluation index, and the preparation was optimized by orthogonal experimental design.
  
  
  RESULTS
  The optimum condition of microcapsules prepared was that 5% gelatin and gum arabic was material, with core material ratio of 1: 2; pH 4.0 and glutaraldehyde in an amount of 1.0 mL. The average encapsulation efficiency of microcapsules of volatile oil from Ledum palustre was 79.62%. Microcapsules was distributed evenly without adhesion through microscopic observation and more than 73% of the microcapsule size distribution between 10 - 14 microm. Microcapsules was spherical and the surface folded by using electron microscope scanning. The test solution and reference solution appeared same spot in the same location compared with the negative control solution.
  
  
  CONCLUSIONS
  The preparation process is simple, stable and feasible.
authors.forename: Man
authors.initials: M
authors.lastname: Lv
mesh_terms: D002214:Capsules; D003692:Delayed-Action Preparations; D004337:Drug Carriers / Q000737:chemistry; D004339:Drug Compounding / Q000379:methods*; D004355:Drug Stability; D005780:Gelatin / Q000008:administration & dosage / Q000737:chemistry*; D005976:Glutaral / Q000008:administration & dosage / Q000737:chemistry; D006170:Gum Arabic / Q000008:administration & dosage / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D029794:Ledum / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D009822:Oils, Volatile / Q000008:administration & dosage / Q000737:chemistry*; D010316:Particle Size; D010938:Plant Oils / Q000008:administration & dosage / Q000737:chemistry; D013499:Surface Properties
chemical_list: D002214:Capsules; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D009822:Oils, Volatile; D010938:Plant Oils; D006170:Gum Arabic; D005780:Gelatin; D005976:Glutaral