title: Enantioposition-selective copper-catalyzed azide-alkyne cycloaddition for construction of chiral biaryl derivatives.
abstract: A highly enantioposition-selective copper-catalyzed azide-alkyne cycloaddition (CuAAC) of dialkynes bearing prochiral biaryls has been developed for the construction of 1,2,3-triazoles bearing axially chiral biaryl groups in up to 76% yield and up to 99% ee.
authors.affiliation: Institute for Molecular Science (IMS), Okazaki, Aichi 444-8787, Japan.
authors.forename: Takao
authors.initials: T
authors.lastname: Osako
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Uozumi