title: Chemical compounds toxic to invertebrates isolated from marine cyanobacteria of potential relevance to the agricultural industry.
abstract: In spite of advances in invertebrate pest management, the agricultural industry is suffering from impeded pest control exacerbated by global climate changes that have altered rain patterns to favour opportunistic breeding. Thus, novel naturally derived chemical compounds toxic to both terrestrial and aquatic invertebrates are of interest, as potential pesticides. In this regard, marine cyanobacterium-derived metabolites that are toxic to both terrestrial and aquatic invertebrates continue to be a promising, but neglected, source of potential pesticides. A PubMed query combined with hand-curation of the information from retrieved articles allowed for the identification of 36 cyanobacteria-derived chemical compounds experimentally confirmed as being toxic to invertebrates. These compounds are discussed in this review.
authors.affiliation: Computational Bioscience Research Center (CBRC), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Jeddah, Saudi Arabia. magbubah.essack@kaust.edu.sa.
authors.forename: Magbubah
authors.initials: M
authors.lastname: Essack
authors.affiliation: Computational Bioscience Research Center (CBRC), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Jeddah, Saudi Arabia. hanin.alzubaidy@kaust.edu.sa.
authors.forename: Hanin S
authors.initials: HS
authors.lastname: Alzubaidy
authors.affiliation: Computational Bioscience Research Center (CBRC), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Jeddah, Saudi Arabia. vladimir.bajic@kaust.edu.sa.
authors.forename: Vladimir B
authors.initials: VB
authors.lastname: Bajic
authors.affiliation: Computational Bioscience Research Center (CBRC), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Jeddah, Saudi Arabia. john.archer@kaust.edu.sa.
authors.forename: John A C
authors.initials: JA
authors.lastname: Archer
mesh_terms: D000818:Animals; D059001:Aquatic Organisms / Q000254:growth & development / Q000378:metabolism*; D001427:Bacterial Toxins / Q000096:biosynthesis / Q000302:isolation & purification*; D057231:Climate Change; D003247:Conservation of Natural Resources; D000458:Cyanobacteria / Q000254:growth & development / Q000378:metabolism*; D007448:Invertebrates / Q000254:growth & development; D008975:Molluscacides / Q000302:isolation & purification / Q000378:metabolism; D010063:Ovum / Q000254:growth & development; D010572:Pest Control, Biological / Q000379:methods*; D010575:Pesticides / Q000302:isolation & purification* / Q000378:metabolism
chemical_list: D001427:Bacterial Toxins; D008975:Molluscacides; D010575:Pesticides