title: Penipyrols A-B and peniamidones A-D from the mangrove derived Penicillium solitum GWQ-143.
abstract: Chemical investigation the extract of Penicillium solitum GWQ-143 led to yield four new compounds penipyrols A-B (1-2) and peniamidones A-B (3-4), together with peniamidones C-D (5-6), which had been previously described as synthetic intermediates, not obtained from natural resource. The structures of those new compounds were established through extensive spectroscopic analysis. Compounds 1-6 exhibited great radical scavenging activities against DPPH with IC50 values ranged from 4.7 to 15.0 μM.
authors.affiliation: Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, People's Republic of China.
authors.forename: Wenqiang
authors.initials: W
authors.lastname: Guo
authors.forename: Xianglan
authors.initials: X
authors.lastname: Kong
authors.forename: Tianjiao
authors.initials: T
authors.lastname: Zhu
authors.forename: Qianqun
authors.initials: Q
authors.lastname: Gu
authors.forename: Dehai
authors.initials: D
authors.lastname: Li
mesh_terms: D016166:Free Radical Scavengers / Q000737:chemistry* / Q000302:isolation & purification*; D010407:Penicillium / Q000737:chemistry* / Q000302:isolation & purification*; D043982:Rhizophoraceae
chemical_list: D016166:Free Radical Scavengers