title: Designing a new scoring system (QualyP Score) correlating the management of cardiopulmonary bypass to postoperative outcomes.
abstract: OBJECTIVE
  The aim of this study was to ascertain if a score, directly derived from CPB records, could correlate to major postoperative outcomes.
  
  
  METHODS
  An additive score (QualyP Score) was created from 10 parameters: peak lactate value during CPB, peak VCO(2)i, lowest DO(2)i/VCO(2)i, peak respiratory quotient, CPB time, cross-clamp time, lowest CPB temperature, circulatory arrest, ultrafiltration during CPB, number of packed red cells transfused intraoperatively. The PerfSCORE was calculated, as well. Multivariable logistic regression models were built to detect the independent predictors of: peak lactate >3 mmol/L during the first three postoperative days; the incidence of acute kidney injury network (AKIN) 1-2-3; respiratory insufficiency; mortality.
  
  
  RESULTS
  The mean score was 4.8±2.6 (0-10). A QualyP Score ≥1 was predictive of postoperative acidosis (OR=1.595). A score ≥2 was predictive of AKIN 2 (OR=1.268) and respiratory insufficiency (OR=1.526). A score ≥5 was predictive of AKIN 3 (OR=1.848) and mortality (OR=1.497).
  
  
  CONCLUSIONS
  QualyP Score may help to provide a quality marker of perfusion, emphasizing the need for goal-directed perfusion strategies.
authors.affiliation: Cardiac Surgery Unit, A.O.U. "Policlinico-Vittorio Emanuele", Ferrarotto Hospital, University of Catania, Catania, Italy antonio.rubino@hotmail.com.
authors.forename: A S
authors.initials: AS
authors.lastname: Rubino
authors.affiliation: Perfusion Service, Cardiac Surgery Unit, Ferrarotto Hospital, University of Catania, Catania, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Torrisi
authors.affiliation: Perfusion Service, Cardiac Surgery Unit, Ferrarotto Hospital, University of Catania, Catania, Italy.
authors.forename: I
authors.initials: I
authors.lastname: Milazzo
authors.affiliation: Cardiac Surgery Unit, GVM Care and Research, Maria Eleonora Hospital, Palermo, Italy.
authors.forename: K
authors.initials: K
authors.lastname: Fattouch
authors.affiliation: Perfusion Service, Cardiac Surgery Unit, Ferrarotto Hospital, University of Catania, Catania, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Busà
authors.affiliation: Cardiac Surgery Unit, A.O.U. "Policlinico-Vittorio Emanuele", Ferrarotto Hospital, University of Catania, Catania, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Mariani
authors.affiliation: Cardiac Surgery Unit, A.O.U. "Policlinico-Vittorio Emanuele", Ferrarotto Hospital, University of Catania, Catania, Italy.
authors.forename: S
authors.initials: S
authors.lastname: D'Aleo
authors.affiliation: Perfusion Service, Cardiac Surgery Unit, Ferrarotto Hospital, University of Catania, Catania, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Giammona
authors.affiliation: Perfusion Service, Cardiac Surgery Unit, Ferrarotto Hospital, University of Catania, Catania, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Sferrazzo
authors.affiliation: Cardiac Surgery Unit, A.O.U. "Policlinico-Vittorio Emanuele", Ferrarotto Hospital, University of Catania, Catania, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Mignosa
mesh_terms: D000368:Aged; D015415:Biomarkers / Q000097:blood; D002245:Carbon Dioxide / Q000097:blood*; D002315:Cardiopulmonary Bypass / Q000009:adverse effects*; D005260:Female; D006801:Humans; D019344:Lactic Acid / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000097:blood*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012189:Retrospective Studies
chemical_list: D015415:Biomarkers; D002245:Carbon Dioxide; D019344:Lactic Acid
keywords: perfusion; quality; risk score