title: Postoperative medical complications associated with anesthesia in older adults with dementia.
abstract: OBJECTIVE
  To examine the association between anesthetic technique and postoperative complications in older adults with dementia undergoing hip fracture surgery.
  
  
  METHODS
  Population-based, retrospective cohort study.
  
  
  METHODS
  Ontario, Canada.
  
  
  METHODS
  All older adults with dementia who underwent surgery for hip fracture repair in Ontario, Canada, between April 1, 2003 and March 31, 2011.
  
  
  METHODS
  The baseline characteristics of individuals who received general anesthesia (GA) and regional anesthesia (RA) were compared. Individuals who received GA were matched to similar individuals who received RA using propensity scores to control for confounding, and their outcomes compared, including 30-day mortality, intensive care unit (ICU) admissions, specific postoperative medical complications, and hospital length of stay (LOS).
  
  
  RESULTS
  In the 6,135 matched pairs, there was no statistically significant difference in postoperative 30-day mortality (GA, 11.3%; RA, 10.8%, P = .44). There were no statistically significant differences in the rates of specific postoperative medical complications or LOS in the two anesthetic groups, but GA was associated with higher rates of ICU admissions (6.1% vs 4.2%, P < .001).
  
  
  CONCLUSIONS
  For older adults with dementia undergoing hip fracture surgery, GA and RA are associated with similar rates of most perioperative adverse events. Further studies are required to determine the optimal methods of providing anesthesia and perioperative care for older adults with dementia undergoing surgical procedures.
authors.affiliation: Department of Psychiatry, Queen's University, Kingston, Ontario, Canada.
authors.forename: Dallas P
authors.initials: DP
authors.lastname: Seitz
authors.forename: Sudeep S
authors.initials: SS
authors.lastname: Gill
authors.forename: Chaim M
authors.initials: CM
authors.lastname: Bell
authors.forename: Peter C
authors.initials: PC
authors.lastname: Austin
authors.forename: Andrea
authors.initials: A
authors.lastname: Gruneir
authors.forename: Geoff M
authors.initials: GM
authors.lastname: Anderson
authors.forename: Paula A
authors.initials: PA
authors.lastname: Rochon
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000150:complications* / Q000401:mortality; D000765:Anesthesia, Conduction / Q000009:adverse effects*; D000768:Anesthesia, General / Q000009:adverse effects*; D015331:Cohort Studies; D015897:Comorbidity; D005260:Female; D006620:Hip Fractures / Q000401:mortality / Q000601:surgery*; D006801:Humans; D007362:Intensive Care Units / Q000706:statistics & numerical data; D007902:Length of Stay / Q000706:statistics & numerical data; D008134:Long-Term Care / Q000706:statistics & numerical data; D008297:Male; D016555:Matched-Pair Analysis; D009864:Ontario; D010343:Patient Admission / Q000706:statistics & numerical data; D011183:Postoperative Complications / Q000209:etiology* / Q000401:mortality; D057216:Propensity Score; D016019:Survival Analysis
keywords: Alzheimer's disease; anesthesia; dementia; hip fracture; surgery