title: [Cognitive impairment, nutritional status and clinical profile in chronic obstructive pulmonary disease].
abstract: BACKGROUND
  Chronic obstructive pulmonary disease (COPD) is a progressive disease with a prevalence that increases with the aging of the subject. It presents a high prevalence of comorbidities, such as cognitive decline, which is gaining great clinical relevance in recent years. Factors such as pulmonary function, hypoxemia, hypercapnia or exacerbations contribute to the decline of cognitive functions. The nutritional status has been added to these factors as contributing to cognitive function decline when presenting in COPD.
  
  
  OBJECTIVE
  To evidence the relationship between cognitive decline, nutritional status and the clinical profile of patients admitted because of an acute exacerbation of COPD (AECOPD).
  
  
  METHODS
  110 subjects hospitalized because of COPD, divided in two groups according to their nutritional status and assessment of cognitive decline at admittance, nutritional status and clinical profile.
  
  
  RESULTS
  Significant differences between groups concerning nutritional status in anthropometric variables (sex and IMC), functional ability (Barthel index and Daily Life Activities Scale), quality of life (Euroqol- 5D y SGRQ), sleep quality (Pittsburgh), mood (HAD) and cognitive decline (MoCa attention, MoCa abstraction). (p<0.05).
  
  
  CONCLUSIONS
  Cognitive function is affected in COPD patients with an altered nutritional status when compared to those with a normal nutritional status. The nutritional decline is a factor contributing to the impairment of cognitive functions in this kind of patients, particularly a decline in attention and abstraction ability.
authors.affiliation: Departamento de Fisioterapia. Facultad de Ciencias de la Salud. Universidad de Granada. España.. ysavel@correo.ugr.es.
authors.forename: Isabel
authors.initials: I
authors.lastname: López Torres
authors.affiliation: Departamento de Fisioterapia. Facultad de Ciencias de la Salud. Universidad de Granada. España.. irene91@correo.ugr.es.
authors.forename: Irene
authors.initials: I
authors.lastname: Torres-Sánchez
authors.affiliation: Departamento de Fisioterapia. Facultad de Ciencias de la Salud. Universidad de Granada. España.. ade12@correo.ugr.es.
authors.forename: Adelina
authors.initials: A
authors.lastname: Martín Salvador
authors.affiliation: Departamento de Fisioterapia. Facultad de Ciencias de la Salud. Universidad de Granada. España.. arorru@correo.ugr.es.
authors.forename: Araceli
authors.initials: A
authors.lastname: Ortiz Rubio
authors.affiliation: Departamento de Fisioterapia. Facultad de Ciencias de la Salud. Universidad de Granada. España.. elypsea88@gmail.com.
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Rodríguez Alzueta
authors.affiliation: Departamento de Fisioterapia. Facultad de Ciencias de la Salud. Universidad de Granada. España.. cvalenza@ugr.es.
authors.forename: Marie Carmen
authors.initials: MC
authors.lastname: Valenza
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003072:Cognition Disorders / Q000453:epidemiology* / Q000523:psychology; D005260:Female; D006801:Humans; D007297:Inpatients; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology* / Q000523:psychology*; D011788:Quality of Life