title: Meal-induced blood pressure fall in patients with isolated morning hypertension.
abstract: We aimed to determine a possible association between isolated morning hypertension (IMH) and meal-induced blood pressure (BP) fall in adult treated hypertensive patients who underwent home BP measurements. A total of 230 patients were included, median age 73.6, 65.2% women. After adjusting for age, sex, number of antihypertensive drugs, office and home BP levels, the association between IMH and meal-induced BP fall was statistically significant. In conclusion, meal-induced BP fall and IMH detected through home blood pressure monitoring (HBPM) are independently associated in hypertensive patients. The therapeutic implications of such observation need to be clarified in large-scale prospective studies.
authors.affiliation: Hypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires , Buenos Aires , Argentina.
authors.forename: Jessica
authors.initials: J
authors.lastname: Barochiner
authors.forename: José
authors.initials: J
authors.lastname: Alfie
authors.forename: Lucas S
authors.initials: LS
authors.lastname: Aparicio
authors.forename: Paula E
authors.initials: PE
authors.lastname: Cuffaro
authors.forename: Marcelo A
authors.initials: MA
authors.lastname: Rada
authors.forename: Margarita S
authors.initials: MS
authors.lastname: Morales
authors.forename: Carlos R
authors.initials: CR
authors.lastname: Galarza
authors.forename: Marcos J
authors.initials: MJ
authors.lastname: Marín
authors.forename: Gabriel D
authors.initials: GD
authors.lastname: Waisman
mesh_terms: D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001794:Blood Pressure / Q000502:physiology*; D018660:Blood Pressure Monitoring, Ambulatory; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology*; D007022:Hypotension / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D062407:Meals / Q000502:physiology*; D019518:Postprandial Period / Q000502:physiology*; D011446:Prospective Studies; D013997:Time Factors
chemical_list: D000959:Antihypertensive Agents
keywords: Home blood pressure; hypertension; isolated morning hypertension; postprandial blood pressure; postprandial hypotension