title: Immune Response of Salmonella Challenged Broiler Chickens Fed Diets Containing Gallipro®, a Bacillus subtilis Probiotic.
abstract: This study was conducted to investigate the effect of feeding a probiotic, Bacillus subtilis, on antibody titers against Newcastle and infectious bursal viruses in broiler chickens challenged with Salmonella enterica serotype Enteritidis. One hundred and sixty 1-day-old broiler chicks were randomly assigned to four treatments in a completely randomized design. The treatments were negative control, probiotic-treated group, challenged group, and challenged probiotic treated group. Salmonella challenging decreased (P < 0.05) the relative weights of spleen and bursa. Inclusion of probiotic to diet of challenged chickens increased the relative weight of spleen, but had no effect on the relative weight of bursa. There were no differences for the antibody titers of chickens between negative control and probiotic-treated group. Salmonella challenging decreased (P < 0.05) antibody titers against Newcastle and infectious bursal viruses. Improvements in the antibody titers were observed by the addition of probiotic to diet of these chickens. The results showed that dietary inclusion of probiotic had no significant effect on immune parameters of chickens at non-contaminated environment, display a greater efficacy at environment contaminated with pathogen and can improve immune responses of infected chickens.
authors.affiliation: Department of Animal Science, Science and Research Branch, Islamic Azad University, Tehran, Iran, a.sadeghi@srbiau.ac.ir.
authors.forename: Ali Asghar
authors.initials: AA
authors.lastname: Sadeghi
authors.forename: Parvin
authors.initials: P
authors.lastname: Shawrang
authors.forename: Shirin
authors.initials: S
authors.lastname: Shakorzadeh
mesh_terms: D000821:Animal Feed / Q000382:microbiology; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D001412:Bacillus subtilis; D018175:Birnaviridae Infections / Q000276:immunology* / Q000382:microbiology / Q000628:therapy; D002645:Chickens / Q000382:microbiology* / Q000821:virology; D004032:Diet / Q000662:veterinary; D007243:Infectious bursal disease virus; D009521:Newcastle Disease / Q000276:immunology* / Q000382:microbiology / Q000628:therapy; D009929:Organ Size; D011201:Poultry Diseases / Q000276:immunology* / Q000628:therapy / Q000821:virology; D019936:Probiotics; D012477:Salmonella enteritidis / Q000472:pathogenicity*; D013154:Spleen / Q000382:microbiology / Q000821:virology; D014611:Vaccination
chemical_list: D000914:Antibodies, Viral