title: The rat endovascular perforation model of subarachnoid hemorrhage.
abstract: The rat endovascular perforation model is considered the closest replica of human condition. Since its development, this model has been extensively used to study early brain injury after subarachnoid hemorrhage (SAH). However, like any other animal model, it has advantages and limitations. The following is a brief review of the rat endovascular perforation SAH model. One section is dedicated to technical considerations that can be used to overcome the model limitations.
authors.affiliation: Departments of Neurosurgery and Neurosciences, Mount Sinai School of Medicine, 1 Gustave L. Levy Place, New York, NY, 10029, USA, fatima.sehba@mssm.edu.
authors.forename: Fatima A
authors.initials: FA
authors.lastname: Sehba
mesh_terms: D000818:Animals; D002560:Cerebrovascular Circulation / Q000502:physiology*; D004195:Disease Models, Animal; D057510:Endovascular Procedures / Q000379:methods*; D051381:Rats; D013345:Subarachnoid Hemorrhage / Q000503:physiopathology*