title: Gastric hepatoid adenocarcinoma: a computed tomography report of six cases.
abstract: We describe the computed tomography (CT) imaging findings in six cases (five males and one female; age range 61-78 years; mean age 67.3 years) with histologically proven hepatoid adenocarcinoma of the stomach (HAS). Five of the six patients had elevated serum alpha-fetoprotein levels. The most common type of gross appearance HAS on CT is a polypoid mass (83%, 5/6). The most common contrast enhancement pattern was heterogeneous. All six patients had a regional lymphadenopathy larger than 6 mm in its short axis. Liver metastases (n = 3) were noted. Venous tumor thrombosis was identified in the portal vein (n = 2) of the regions near primary gastric tumors or metastatic masses. Our findings suggest in an elderly, male patients with a large heterogeneous enhancement tumor, the presence of distant metastases, regional lymphadenopathy and characteristically increased serum alpha-fetoprotein levels indicates a high likelihood of HAS.
authors.affiliation: An Ren, Yan-Ning Shang, En-Sen Ma, Zhen-Guo Huang, Wu Wang, Jie Luo, Department of Radiology, China-Japan Friendship Hospital, Beijing 100029, China.
authors.forename: An
authors.initials: A
authors.lastname: Ren
authors.affiliation: An Ren, Yan-Ning Shang, En-Sen Ma, Zhen-Guo Huang, Wu Wang, Jie Luo, Department of Radiology, China-Japan Friendship Hospital, Beijing 100029, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Cai
authors.affiliation: An Ren, Yan-Ning Shang, En-Sen Ma, Zhen-Guo Huang, Wu Wang, Jie Luo, Department of Radiology, China-Japan Friendship Hospital, Beijing 100029, China.
authors.forename: Yan-Ning
authors.initials: YN
authors.lastname: Shang
authors.affiliation: An Ren, Yan-Ning Shang, En-Sen Ma, Zhen-Guo Huang, Wu Wang, Jie Luo, Department of Radiology, China-Japan Friendship Hospital, Beijing 100029, China.
authors.forename: En-Sen
authors.initials: ES
authors.lastname: Ma
authors.affiliation: An Ren, Yan-Ning Shang, En-Sen Ma, Zhen-Guo Huang, Wu Wang, Jie Luo, Department of Radiology, China-Japan Friendship Hospital, Beijing 100029, China.
authors.forename: Zhen-Guo
authors.initials: ZG
authors.lastname: Huang
authors.affiliation: An Ren, Yan-Ning Shang, En-Sen Ma, Zhen-Guo Huang, Wu Wang, Jie Luo, Department of Radiology, China-Japan Friendship Hospital, Beijing 100029, China.
authors.forename: Wu
authors.initials: W
authors.lastname: Wang
authors.affiliation: An Ren, Yan-Ning Shang, En-Sen Ma, Zhen-Guo Huang, Wu Wang, Jie Luo, Department of Radiology, China-Japan Friendship Hospital, Beijing 100029, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Luo
mesh_terms: D000230:Adenocarcinoma / Q000097:blood / Q000145:classification / Q000000981:diagnostic imaging* / Q000556:secondary / Q000628:therapy; D000368:Aged; D001706:Biopsy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000145:classification / Q000000981:diagnostic imaging* / Q000556:secondary / Q000628:therapy; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D018000:Receptors, Peptide / Q000097:blood; D013274:Stomach Neoplasms / Q000097:blood / Q000145:classification / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D009626:Terminology as Topic; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D018000:Receptors, Peptide; C042144:alpha-fetoprotein receptor, human
keywords: Hepatoid adenocarcinoma; Metastasis; Portal venous thrombosis; Stomach; Tomography, X-ray