title: Comparison of costs and discharge outcomes for patients hospitalized for ischemic or hemorrhagic stroke with or without atrial fibrillation in the United States.
abstract: This retrospective analysis investigated the impact of baseline clinical characteristics, including atrial fibrillation (AF), on hospital discharge status (to home or continuing care), mortality, length of hospital stay, and treatment costs in patients hospitalized for stroke. The analysis included adult patients hospitalized with a primary diagnosis of ischemic or hemorrhagic stroke between January 2006 and June 2011 from the premier alliance database, a large nationally representative database of inpatient health records. Patients included in the analysis were categorized as with or without AF, based on the presence or absence of a secondary listed diagnosis of AF. Irrespective of stroke type (ischemic or hemorrhagic), AF was associated with an increased risk of mortality during the index hospitalization event, as well as a higher probability of discharge to a continuing care facility, longer duration of stay, and higher treatment costs. In patients hospitalized for a stroke event, AF appears to be an independent risk factor of in-hospital mortality, discharge to continuing care, length of hospital stay, and increased treatment costs.
authors.affiliation: Global Health Economics and Outcomes Research, Bristol-Myers Squibb Company, 5 Research Parkway, Wallingford, CT, 06492, USA, xianying.pan@bms.com.
authors.forename: Xianying
authors.initials: X
authors.lastname: Pan
authors.forename: Teresa A
authors.initials: TA
authors.lastname: Simon
authors.forename: Melissa
authors.initials: M
authors.lastname: Hamilton
authors.forename: Andreas
authors.initials: A
authors.lastname: Kuznik
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001281:Atrial Fibrillation / Q000150:complications / Q000191:economics / Q000401:mortality / Q000628:therapy; D002545:Brain Ischemia / Q000150:complications / Q000191:economics / Q000401:mortality / Q000628:therapy; D002543:Cerebral Hemorrhage / Q000150:complications / Q000191:economics / Q000401:mortality / Q000628:therapy; D003365:Costs and Cost Analysis; D016208:Databases, Factual; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010351:Patient Discharge / Q000191:economics*; D012189:Retrospective Studies; D012307:Risk Factors; D020521:Stroke / Q000150:complications / Q000191:economics / Q000401:mortality / Q000628:therapy; D014481:United States / Q000453:epidemiology