title: Rare is frequent and frequent is costly: rare diseases as a challenge for health care systems.
authors.affiliation: Center for Health Economics Research Hannover, Leibniz University Hannover, Königsworther Platz 1, 30167, Hannover, Germany, jms@ivbl.uni-hannover.de.
authors.forename: J-Matthias
authors.initials: JM
authors.lastname: Graf von der Schulenburg
authors.forename: Martin
authors.initials: M
authors.lastname: Frank
mesh_terms: D003695:Delivery of Health Care / Q000191:economics / Q000458:organization & administration*; D004345:Drug Industry / Q000191:economics; D005060:Europe; D006285:Health Planning / Q000458:organization & administration; D006801:Humans; D057240:Patient Preference; D035583:Rare Diseases / Q000191:economics* / Q000453:epidemiology*