title: Correlation between the pressure-to-cornea index and both structural and functional measures of glaucoma.
abstract: OBJECTIVE
  the pressure-to-cornea index (PCI) was proposed in order to integrate intraocular pressure and central cornea thickness as a single-risk factor for glaucoma. The purpose of this study was to correlate the PCI with a structural and two functional measures of glaucoma.
  
  
  METHODS
  University Hospital in South America.
  
  
  METHODS
  Pressure-to-cornea index was calculated for 70 eyes of 36 subjects (glaucoma and suspects). Cup-to-disc (C/D) ratio, mean deviation (MD) and pattern standard deviation (PSD) as recorded by Humphrey automated perimetry (SITA 24-2) were correlated with PCI (Pearson's correlation coefficient).
  
  
  RESULTS
  Pearson's correlation coefficient between PCI and C/D was 0.329 (95% confidence interval [95% CI], 0.09-0.526; P = 0.006); between PCI and MD was - 0.356 MD (95% CI, -0.549 to - 0.126; P = 0.003); and between PCI and PSD was - 0.215 (95% CI, -0.433 to 0.025; P = 0.07).
  
  
  CONCLUSIONS
  In addition to serve as a single-risk factor, PCI can be used to stage glaucoma severity as well.
authors.forename: Andrea Mbv
authors.initials: AM
authors.lastname: Franco
authors.affiliation: Department of Ophthalmology, Brotherhood of Santa Casa de Misericordia de Sao Paulo, Santa Casa de São Paulo School of Medical Sciences, Sao Paulo, Brazil.
authors.forename: Niro
authors.initials: N
authors.lastname: Kasahara
mesh_terms: D000328:Adult; D000368:Aged; D003315:Cornea / Q000473:pathology* / Q000503:physiopathology*; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014065:Tonometry, Ocular; D014794:Visual Fields / Q000502:physiology*