title: Left atrial function assessed by left atrial strain in patients with left circumflex branch culprit acute myocardial infarction.
abstract: BACKGROUND
  Although left atrium (LA) has played an important role in diastole, ischemic insult of atrium in acute myocardial infarction (AMI) has not been clearly evaluated.
  
  
  METHODS
  We hypothesized that LA function would be further decreased in AMI patients with a culprit lesion in the left circumflex branch (LCX). This was an observational cohort study in a single university hospital. Echocardiography was performed to evaluate left ventricular diastolic function, LA volume, and LA function. Systolic (LAS ) and late diastolic (LAA ) LA strain were measured using speckle tracking echocardiography.
  
  
  RESULTS
  Sixty-eight AMI patients treated with emergent or urgent percutaneous coronary intervention were enrolled. Global LAS strain was significantly lower in patients with a culprit lesion in the LCX than culprit lesions in other vessels (left anterior descending, 27.3 ± 6.8%; left circumflex, 20.1 ± 8.9%; right coronary artery, 23.3 ± 6.5%; P = 0.007). LA volume index did not differ significantly (P = 0.093). Other clinical and conventional echocardiographic parameters, including Doppler measurements, did not differ significantly.
  
  
  CONCLUSIONS
  Global LAS strain was lower in AMI patients with a culprit lesion in the LCX than those with culprit lesions in other vessels, without any significant difference in LA volume index. The lower global LAS strain might suggest decreased LA function resulting from ischemic insult by AMI with culprit lesions in the LCX.
authors.affiliation: Department of Cardiology, Dong-A University Hospital, Busan, Korea.
authors.forename: Dong Hyun
authors.identifier: http://orcid.org/0000-0001-6253-3396
authors.initials: DH
authors.lastname: Lee
authors.affiliation: Department of Cardiology, Dong-A University Hospital, Busan, Korea.
authors.forename: Tae-Ho
authors.initials: TH
authors.lastname: Park
authors.affiliation: Department of Cardiology, Dong-A University Hospital, Busan, Korea.
authors.forename: Jung Eun
authors.initials: JE
authors.lastname: Lee
authors.affiliation: Department of Cardiology, Dong-A University Hospital, Busan, Korea.
authors.forename: Young-Rak
authors.initials: YR
authors.lastname: Cho
authors.affiliation: Department of Cardiology, Dong-A University Hospital, Busan, Korea.
authors.forename: Kyungil
authors.initials: K
authors.lastname: Park
authors.affiliation: Department of Cardiology, Dong-A University Hospital, Busan, Korea.
authors.forename: Jong Sung
authors.initials: JS
authors.lastname: Park
authors.affiliation: Department of Cardiology, Dong-A University Hospital, Busan, Korea.
authors.forename: Moo-Hyun
authors.initials: MH
authors.lastname: Kim
authors.affiliation: Department of Cardiology, Dong-A University Hospital, Busan, Korea.
authors.forename: Young-Dae
authors.initials: YD
authors.lastname: Kim
mesh_terms: D000208:Acute Disease; D015331:Cohort Studies; D005260:Female; D006325:Heart Atria / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D014463:Ultrasonography
keywords: atrium; diastolic dysfunction; echocardiography; myocardial infarction