title: A comprehensive review of the structure elucidation and biological activity of triterpenoids from Ganoderma spp.
abstract: Ganoderma triterpenes (GTs) are the major secondary metabolites of Ganoderma lucidum, a traditional Chinese medicine, popularly used for complementary cancer therapy. GTs are lanostane-tetracyclic triterpenes. They have been reported to possess anti-tumor, anti-inflammation, antioxidant, antimicrobial and blood fat reducing effects. To date, 316 GTs have been found and their similar chemical structures have proved difficult to elucidate. This paper compiles 316 naturally occurring triterpenes from Ganoderma based on the literature published through January 2013 along with their structures, physiological activities and 13C-NMR spectral data.
authors.affiliation: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China. sdxq1021@163.com.
authors.forename: Qing
authors.initials: Q
authors.lastname: Xia
authors.affiliation: School of Basic Medical Sciences, Beijing University of Chinese Medicine, Beijing 100029, China. zhanghuazheng1109@163.com.
authors.forename: Huazheng
authors.initials: H
authors.lastname: Zhang
authors.affiliation: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China. sunxuefei.2008@163.com.
authors.forename: Xuefei
authors.initials: X
authors.lastname: Sun
authors.affiliation: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China. zhaohaijuan2010@163.com.
authors.forename: Haijuan
authors.initials: H
authors.lastname: Zhao
authors.affiliation: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China. fanglingwu@163.com.
authors.forename: Lingfang
authors.initials: L
authors.lastname: Wu
authors.affiliation: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China. hbbdzhudan@163.com.
authors.forename: Dan
authors.initials: D
authors.lastname: Zhu
authors.affiliation: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China. yghui1990@163.com.
authors.forename: Guanghui
authors.initials: G
authors.lastname: Yang
authors.affiliation: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China. sunshine4003@126.com.
authors.forename: Yanyan
authors.initials: Y
authors.lastname: Shao
authors.affiliation: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China. zhangxiaoxue122@163.com.
authors.forename: Xiaoxue
authors.initials: X
authors.lastname: Zhang
authors.affiliation: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China. mxmaoxin@126.com.
authors.forename: Xin
authors.initials: X
authors.lastname: Mao
authors.affiliation: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China. zhanglanzhen01@126.com.
authors.forename: Lanzhen
authors.initials: L
authors.lastname: Zhang
authors.affiliation: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China. shegaimei@126.com.
authors.forename: Gaimei
authors.initials: G
authors.lastname: She
mesh_terms: D000818:Animals; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000494:pharmacology*; D032902:Ganoderma / Q000737:chemistry*; D006801:Humans; D051379:Mice; D013329:Structure-Activity Relationship; D014315:Triterpenes / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D004365:Drugs, Chinese Herbal; D014315:Triterpenes