title: Validation of the new IASLC/ATS/ERS lung adenocarcinoma classification: a surgeon's perspective.
abstract: The conclusions from the new IASLC/ATS/ERS lung adenocarcinoma classification portend important clinical consequences. The interpretation of the histological, biomolecular and radiological correlates of this classification not only allows for the definitive abandonment of the bronchoalveolar carcinoma definition but provides surgeons with significant clues to better understand the adenocarcinoma subsets and their surgical management. Indeed, the information will benefit surgeons who are fully involved in the lung cancer CT screening programs as well as in the diagnostic and therapeutic pathways of both early and locally advanced lung cancer. Moreover, intriguing perspectives are disclosing on the inclusion of the surgical modality among the ones used in the oligometastatic disease status. On the other hand, the new adenocarcinoma classification also emphasizes the need for surgeons working in a multidisciplinary environment to be thoroughly cognizant of the ever evolving lung cancer biomolecular knowledge and, in particular, of the potentially druggable somatic mutations in line with the modern professional profile of the so-called "surgeon scientist".
authors.affiliation: 1 Department of Surgery, Campus Biomedico University, Rome, Italy ; 2 Division of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, USA ; 3 Departments of Thoracic Surgery and Oncology and Pathology, Istituto Nazionale Tumori, IRCCS, Fondazione "G.Pascale", Naples, Italy.
authors.forename: Raffaele
authors.initials: R
authors.lastname: Rocco
authors.affiliation: 1 Department of Surgery, Campus Biomedico University, Rome, Italy ; 2 Division of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, USA ; 3 Departments of Thoracic Surgery and Oncology and Pathology, Istituto Nazionale Tumori, IRCCS, Fondazione "G.Pascale", Naples, Italy.
authors.forename: David R
authors.initials: DR
authors.lastname: Jones
authors.affiliation: 1 Department of Surgery, Campus Biomedico University, Rome, Italy ; 2 Division of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, USA ; 3 Departments of Thoracic Surgery and Oncology and Pathology, Istituto Nazionale Tumori, IRCCS, Fondazione "G.Pascale", Naples, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Morabito
authors.affiliation: 1 Department of Surgery, Campus Biomedico University, Rome, Italy ; 2 Division of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, USA ; 3 Departments of Thoracic Surgery and Oncology and Pathology, Istituto Nazionale Tumori, IRCCS, Fondazione "G.Pascale", Naples, Italy.
authors.forename: Renato
authors.initials: R
authors.lastname: Franco
authors.affiliation: 1 Department of Surgery, Campus Biomedico University, Rome, Italy ; 2 Division of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, USA ; 3 Departments of Thoracic Surgery and Oncology and Pathology, Istituto Nazionale Tumori, IRCCS, Fondazione "G.Pascale", Naples, Italy.
authors.forename: Elvira
authors.initials: E
authors.lastname: La Mantia
authors.affiliation: 1 Department of Surgery, Campus Biomedico University, Rome, Italy ; 2 Division of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, USA ; 3 Departments of Thoracic Surgery and Oncology and Pathology, Istituto Nazionale Tumori, IRCCS, Fondazione "G.Pascale", Naples, Italy.
authors.forename: Gaetano
authors.initials: G
authors.lastname: Rocco
keywords: Adenocarcinoma; lung cancer; thoracic surgery