title: [Innovation in differential diagnosis and monitoring of rational therapy in patients with lumbosacral radiculopathies].
abstract: OBJECTIVE
  Unfortunately, nowadays there are no reliable ways to predict the outcomes of the conservative treatment in patients with dorsopathies. Otherwise, we could identify patients that demand intensive treatment including therapeutic blockades. We approbated and modified a method for assessment of radicular latency duration in patients with lumbosacral radiculopathies to evaluate its diagnostic value and the possibility of using in monitoring of effectiveness of conservative treatment.
  
  
  METHODS
  We studied the effectiveness of conservative treatment in 60 patients with lumbosacral dorsopathies, including 35 patients manifested with exacerbation of sciatica and 25 patients diagnosed with failed back surgery syndrome (FBSS).
  
  
  RESULTS
  There was a definite resistance to treatment in patients with FBSS. The complex management of patients, including neuromidin and epidural glucocorticoid blockades, demonstrated the greater effectiveness. The evaluation of radicular latency duration with neuromidin test turned out to have important predictive value which could be used to stratify treatment of patients with dorsopathies.
authors.forename: S A
authors.initials: SA
authors.lastname: Zhivolupov
authors.forename: M N
authors.initials: MN
authors.lastname: Vorob'eva
authors.forename: I N
authors.initials: IN
authors.lastname: Samartsev
authors.forename: N A
authors.initials: NA
authors.lastname: Rashidov
mesh_terms: D000328:Adult; D000368:Aged; D000634:Aminoquinolines / Q000627:therapeutic use; D000767:Anesthesia, Epidural; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use; D003937:Diagnosis, Differential; D016903:Drug Monitoring; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D017116:Low Back Pain / Q000175:diagnosis* / Q000188:drug therapy* / Q000503:physiopathology; D008161:Lumbosacral Region / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009407:Nerve Block; D011843:Radiculopathy / Q000175:diagnosis* / Q000188:drug therapy* / Q000503:physiopathology; D055815:Young Adult
chemical_list: D000634:Aminoquinolines; D002800:Cholinesterase Inhibitors; D005938:Glucocorticoids; C049860:amiridine