title: A 290 mV Sub-V(T) ASIC for Real-Time Atrial Fibrillation Detection.
abstract: A real-time detector for episodes of atrial fibrillation is fabricated as an application specific integrated circuit (ASIC). The basis for detection is a set of three parameters for characterizing the RR interval series, i.e., turning point ratio, root mean square of successive differences, and Shannon entropy. The developed hardware architecture targets ultra-low voltage operation, suitable for implantable loop recorders with ultra-low energy requirements. Algorithmic and architectural optimizations are performed to minimize area and energy dissipation, with a total area footprint reduction of 44%. The design is fabricated in 65-nm CMOS low-leakage high-threshold technology. Measurements with aggressively scaled supply voltage (VDD) in the subthreshold (sub-VT) region show energy savings of up to 41 X when operating at 1 kHz with a VDD of 300 mV compared to a nominal VDD of 1.2 V.
authors.forename: Oskar
authors.initials: O
authors.lastname: Andersson
authors.forename: Ki H
authors.initials: KH
authors.lastname: Chon
authors.forename: Leif
authors.initials: L
authors.lastname: Sornmo
authors.forename: Joachim Neves
authors.initials: JN
authors.lastname: Rodrigues
mesh_terms: D000465:Algorithms; D001281:Atrial Fibrillation / Q000503:physiopathology*; D004562:Electrocardiography / Q000295:instrumentation*; D004867:Equipment Design; D006801:Humans; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*