title: Successful Treatment of Severe Right-Sided Heart Failure Due to Postoperative Constrictive Pericarditis With Tolvaptan.
abstract: The prognosis of inoperative constrictive pericarditis is poor due to subsequent severe right-sided heart failure that is refractory to conventional medical treatment. This case report describes the long-term treatment with tolvaptan, a new selective vasopression V2-receptor antagonist, was remarkably effective for inoperative constrictive pericarditis. Despite that tolvaptan was approved for the treatment of hyponatremia in Europe and the United States, the indications and treatment duration of it are not yet well established clinically. We propose that tolvaptan could offer an alternative option for the treatment of medically refractory severe right-sided heart failure such as constrictive pericarditis.
authors.affiliation: Division of Cardiology, Second Department of Internal Medicine, Kyorin University School of Medicine, Tokyo, Japan.
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Kanaya
authors.forename: Kenichi
authors.initials: K
authors.lastname: Matsushita
authors.forename: Takumi
authors.initials: T
authors.lastname: Inami
authors.forename: Satoko
authors.initials: S
authors.lastname: Yamasaki
authors.forename: Saiko
authors.initials: S
authors.lastname: Mizumi
authors.forename: Toshinori
authors.initials: T
authors.lastname: Minamishima
authors.forename: Ayumi
authors.initials: A
authors.lastname: Goda
authors.forename: Akiko
authors.initials: A
authors.lastname: Ueda
authors.forename: Konomi
authors.initials: K
authors.lastname: Sakata
authors.forename: Toru
authors.initials: T
authors.lastname: Satoh
authors.forename: Hideaki
authors.initials: H
authors.lastname: Yoshino
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D065092:Antidiuretic Hormone Receptor Antagonists / Q000627:therapeutic use*; D001552:Benzazepines / Q000627:therapeutic use*; D004232:Diuretics / Q000627:therapeutic use; D006333:Heart Failure / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D007668:Kidney / Q000187:drug effects; D008297:Male; D010494:Pericarditis, Constrictive / Q000150:complications*; D011183:Postoperative Complications; D000077602:Tolvaptan
chemical_list: D065092:Antidiuretic Hormone Receptor Antagonists; D001552:Benzazepines; D004232:Diuretics; D000077602:Tolvaptan