title: Rickettsia parkeri rickettsiosis in different ecological regions of Argentina and its association with Amblyomma tigrinum as a potential vector.
abstract: Rickettsia parkeri, a newly recognized tick-borne pathogen of humans in the Americas, is a confirmed cause of spotted fever group rickettsiosis in Argentina. Until recently, almost all cases of R. parkeri rickettsiosis in Argentina have originated from the Paraná River Delta, where entomological surveys have identified populations of R. parkeri-infected Amblyomma triste ticks. In this report, we describe confirmed cases of R. parkeri rickettsiosis from Córdoba and La Rioja provinces, which are located several hundred kilometers inland, and in a more arid ecological region, where A. triste ticks do not occur. Additionally, we identified questing A. tigrinum ticks naturally infected with R. parkeri in Córdoba province. These data provide evidence that another human-biting tick species serves as a potential vector of R. parkeri in Argentina and possibly, other countries of South America.
authors.affiliation: Hospital F. J. Muñiz, Buenos Aires, Argentina; Instituto Nacional de Tecnología Agropecuaria, Consejo Nacional de Investigaciones Científicas y Técnicas, Rafaela, Santa Fe, Argentina; Sanatorio Allende, Córdoba, Argentina; Instituto de Zoonosis Luis Pasteur, Buenos Aires, Argentina; Infectious Diseases Pathology Branch and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia yromer@hotmail.com.
authors.forename: Yamila
authors.initials: Y
authors.lastname: Romer
authors.affiliation: Hospital F. J. Muñiz, Buenos Aires, Argentina; Instituto Nacional de Tecnología Agropecuaria, Consejo Nacional de Investigaciones Científicas y Técnicas, Rafaela, Santa Fe, Argentina; Sanatorio Allende, Córdoba, Argentina; Instituto de Zoonosis Luis Pasteur, Buenos Aires, Argentina; Infectious Diseases Pathology Branch and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
authors.forename: Santiago
authors.initials: S
authors.lastname: Nava
authors.affiliation: Hospital F. J. Muñiz, Buenos Aires, Argentina; Instituto Nacional de Tecnología Agropecuaria, Consejo Nacional de Investigaciones Científicas y Técnicas, Rafaela, Santa Fe, Argentina; Sanatorio Allende, Córdoba, Argentina; Instituto de Zoonosis Luis Pasteur, Buenos Aires, Argentina; Infectious Diseases Pathology Branch and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
authors.forename: Francisco
authors.initials: F
authors.lastname: Govedic
authors.affiliation: Hospital F. J. Muñiz, Buenos Aires, Argentina; Instituto Nacional de Tecnología Agropecuaria, Consejo Nacional de Investigaciones Científicas y Técnicas, Rafaela, Santa Fe, Argentina; Sanatorio Allende, Córdoba, Argentina; Instituto de Zoonosis Luis Pasteur, Buenos Aires, Argentina; Infectious Diseases Pathology Branch and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Cicuttin
authors.affiliation: Hospital F. J. Muñiz, Buenos Aires, Argentina; Instituto Nacional de Tecnología Agropecuaria, Consejo Nacional de Investigaciones Científicas y Técnicas, Rafaela, Santa Fe, Argentina; Sanatorio Allende, Córdoba, Argentina; Instituto de Zoonosis Luis Pasteur, Buenos Aires, Argentina; Infectious Diseases Pathology Branch and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
authors.forename: Amy M
authors.initials: AM
authors.lastname: Denison
authors.affiliation: Hospital F. J. Muñiz, Buenos Aires, Argentina; Instituto Nacional de Tecnología Agropecuaria, Consejo Nacional de Investigaciones Científicas y Técnicas, Rafaela, Santa Fe, Argentina; Sanatorio Allende, Córdoba, Argentina; Instituto de Zoonosis Luis Pasteur, Buenos Aires, Argentina; Infectious Diseases Pathology Branch and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
authors.forename: Joseph
authors.initials: J
authors.lastname: Singleton
authors.affiliation: Hospital F. J. Muñiz, Buenos Aires, Argentina; Instituto Nacional de Tecnología Agropecuaria, Consejo Nacional de Investigaciones Científicas y Técnicas, Rafaela, Santa Fe, Argentina; Sanatorio Allende, Córdoba, Argentina; Instituto de Zoonosis Luis Pasteur, Buenos Aires, Argentina; Infectious Diseases Pathology Branch and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
authors.forename: Aubree J
authors.initials: AJ
authors.lastname: Kelly
authors.affiliation: Hospital F. J. Muñiz, Buenos Aires, Argentina; Instituto Nacional de Tecnología Agropecuaria, Consejo Nacional de Investigaciones Científicas y Técnicas, Rafaela, Santa Fe, Argentina; Sanatorio Allende, Córdoba, Argentina; Instituto de Zoonosis Luis Pasteur, Buenos Aires, Argentina; Infectious Diseases Pathology Branch and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
authors.forename: Cecilia Y
authors.initials: CY
authors.lastname: Kato
authors.affiliation: Hospital F. J. Muñiz, Buenos Aires, Argentina; Instituto Nacional de Tecnología Agropecuaria, Consejo Nacional de Investigaciones Científicas y Técnicas, Rafaela, Santa Fe, Argentina; Sanatorio Allende, Córdoba, Argentina; Instituto de Zoonosis Luis Pasteur, Buenos Aires, Argentina; Infectious Diseases Pathology Branch and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Paddock
mesh_terms: D000328:Adult; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001118:Argentina / Q000453:epidemiology; D019818:Clavulanic Acid / Q000627:therapeutic use; D004269:DNA, Bacterial / Q000235:genetics; D004318:Doxycycline / Q000627:therapeutic use; D017753:Ecosystem; D005260:Female; D006801:Humans; D007303:Insect Vectors; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D012281:Rickettsia / Q000235:genetics / Q000302:isolation & purification; D012282:Rickettsia Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000635:transmission; D013987:Ticks / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D019818:Clavulanic Acid; D004318:Doxycycline