title: First report of the ceftazidimase CTX-M-19 in South America.
abstract: We report the first detection of bla CTX-M-19 in South America, harboured in an Escherichia coli isolate obtained from a urine sample; such an isolate belonged to phylogenetic group A, ST603, and showed a ceftazidimase profile. bla CTX-M-19 was encoded in an approximately 100 kb IncI1/IncF conjugative plasmid, featuring pndAC and hok/sok addiction systems; the β-lactamase gene was flanked upstream by three tandem-like transposons (IS26, IS10 and ISEcp1), inserted one inside the other, and downstream by IS903.
authors.affiliation: Depto. de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina, Universidad de la República Montevideo, Uruguay.
authors.forename: V
authors.initials: V
authors.lastname: García-Fulgueiras
authors.affiliation: Depto. de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina, Universidad de la República Montevideo, Uruguay.
authors.forename: I
authors.initials: I
authors.lastname: Bado
authors.affiliation: Depto. de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina, Universidad de la República Montevideo, Uruguay.
authors.forename: N F
authors.initials: NF
authors.lastname: Cordeiro
authors.affiliation: Depto. de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina, Universidad de la República Montevideo, Uruguay ; Laboratorio Central del Hospital Pereira Rossell-Ministerio de Salud Pública Montevideo, Uruguay.
authors.forename: G
authors.initials: G
authors.lastname: Algorta
authors.affiliation: Depto. de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina, Universidad de la República Montevideo, Uruguay.
authors.forename: R
authors.initials: R
authors.lastname: Vignoli
keywords: CTX-M-19; Ceftazidimase; ESBL; IS26; IS903