title: Comparative analysis of autologous blood transfusion and allogeneic blood transfusion in surgical patients.
abstract: OBJECTIVE
  To investigate application effects of autologous blood transfusion and allogeneic blood transfusion in surgically treated patients receiving spine surgery, abdomen surgery and ectopic pregnancy surgery.
  
  
  METHODS
  130 patients who would undergo selective operations were divided into autologous transfusion group and allogeneic transfusion group. Both groups received the same anesthesia, and there was no significant difference in transfusion volume or fluid infusion volume.
  
  
  RESULTS
  The serum TNF-α level in autologous transfusion group after operation showed a clear upward trend and had significant difference compared with that before operation (P < 0.05). Meanwhile, after operation, the serum TNF-α level in autologous transfusion group was all significantly higher than that allogeneic transfusion group and the comparative difference was statistically significant (P < 0.05). IgG level in treatment group did not significantly fluctuate during perioperative period, but IgG level in allogeneic transfusion group after operation was all significantly lower than that before operation, and there was statistically significant difference between both groups (P < 0.05). At the same time, complement C3 level in treatment group after operation was significantly higher than that before operation (P < 0.05), but complement C3 level in allogeneic transfusion group did not significantly change. After operation, there was statistically significant difference in complement C3 level between both groups (P < 0.05).
  
  
  CONCLUSIONS
  Autologous transfusion is already a widely accepted transfusion method at present, and it can increase TNF-α and complement C3 levels in the body of surgically treated patients to strengthen immune ability against infection.
authors.affiliation: Department of Vascular Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University Guangzhou 510120, China.
authors.forename: Miao-Yun
authors.initials: MY
authors.lastname: Long
authors.affiliation: Department of Spine Surgery, East Hospital, Tongji University School of Medicine Shanghai 200120, China.
authors.forename: Zhong-Han
authors.initials: ZH
authors.lastname: Liu
authors.affiliation: Department of Spine Surgery, East Hospital, Tongji University School of Medicine Shanghai 200120, China.
authors.forename: Jian-Guang
authors.initials: JG
authors.lastname: Zhu
keywords: Autologous blood transfusion; allogeneic blood transfusion; complement; immune function; inflammatory factor