title: An imidazole-appended p-phenylene-Cu(II) ensemble as a chemoprobe for histidine in biological samples.
abstract: A tetra-imidazole-appended tetrakis(p-phenylene)ethylene 1-Cu(2+) ensemble was found to enhance fluorescence upon addition of histidine, but not with any other amino acids. The 1-Cu(2+) ensemble also selectively detected proteins containing histidine residues in a mixture of water and methanol (90 : 10, v/v%). The 1-Cu(2+) ensemble-coated thin-layered chromatography (TLC) plate could also detect histidine quantitatively. Furthermore, the fluorescence emission recovery upon addition of five concentrations of His was ~80% with good linearity.
authors.affiliation: Department of Chemistry and Research Institute of Natural Sciences, Gyeongsang National University, Jinju, South Korea. jonghwa@gnu.ac.kr.
authors.forename: Ka Young
authors.initials: KY
authors.lastname: Kim
authors.forename: Sung Ho
authors.initials: SH
authors.lastname: Jung
authors.forename: Joon-Hwa
authors.initials: JH
authors.lastname: Lee
authors.forename: Shim Sung
authors.initials: SS
authors.lastname: Lee
authors.forename: Jong Hwa
authors.initials: JH
authors.lastname: Jung
mesh_terms: D002855:Chromatography, Thin Layer; D056831:Coordination Complexes / Q000737:chemistry; D003300:Copper / Q000737:chemistry*; D006639:Histidine / Q000032:analysis*; D007093:Imidazoles / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013267:Stilbenes / Q000737:chemistry*
chemical_list: D056831:Coordination Complexes; D007093:Imidazoles; D013267:Stilbenes; D006639:Histidine; D003300:Copper; C029899:imidazole