title: The influence of interleukin-7 receptor α-chain haplotypes on outcome after allogeneic hematopoietic cell transplantation.
abstract: We investigated the influence of IL-7 receptor α-chain (IL-7Rα) gene haplotypes in donors on the outcome of haematopoietic cell transplantation (HCT). Unlike the association between single donor SNPs and HCT outcome found previously, only trends towards association were found here, due to 'dilution' of SNPs into haplotypes.
authors.affiliation: School of Life Sciences, Hasselt University, Biomedical Research Institute and transnationale Universiteit Limburg, Diepenbeek, Belgium.
authors.forename: B
authors.initials: B
authors.lastname: Broux
authors.forename: Z
authors.initials: Z
authors.lastname: Shamim
authors.forename: T
authors.initials: T
authors.lastname: Wang
authors.forename: S
authors.initials: S
authors.lastname: Spellman
authors.forename: M
authors.initials: M
authors.lastname: Haagenson
authors.forename: P
authors.initials: P
authors.lastname: Stinissen
authors.forename: L P
authors.initials: LP
authors.lastname: Ryder
authors.forename: K
authors.initials: K
authors.lastname: Müller
authors.forename: N
authors.initials: N
authors.lastname: Hellings
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005787:Gene Frequency / Q000235:genetics; D006239:Haplotypes / Q000235:genetics*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D020395:Receptors, Interleukin-7 / Q000235:genetics*; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D020395:Receptors, Interleukin-7; C415350:interleukin-7 receptor, alpha chain