title: [Acute posterior multifocal placoid pigment epiteliopathy and neurological involvement in an elderly patient: case report and review].
abstract: We report a rare case of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) in an elderly patient and a review of the recent scientific literature. A 65-year-old Caucasian man, forty-five days after return from tropical travel he developed right-sided facial palsy with right hemiplegia, dysarthria and a positive Babinski sign. He started prednisone 90 mg/day. Clinical, laboratory and imaging examinations were reported. Five months later there was a complete neurological and ophthalmological recovery. Although APMPPE was described primarily in young adults, we report the first case of APMPPE associated with neurological involvement in an older patient with a complete restitutio ad integrum.
authors.affiliation: Dipartimento di Scienze Medico-Chirurgiche, U.O.S. Oftalmologia, Università 'Sapienza' di Roma, Terracina, Italia.
authors.forename: M
authors.initials: M
authors.lastname: Mafrici
authors.affiliation: Dipartimento di Scienze Medico-Chirurgiche, U.O.S. Oftalmologia, Università 'Sapienza' di Roma, Terracina, Italia.
authors.forename: M
authors.initials: M
authors.lastname: Salomone
authors.affiliation: Dipartimento di Scienze Medico-Chirurgiche, U.O.S. Oftalmologia, Università 'Sapienza' di Roma, Terracina, Italia.
authors.forename: S
authors.initials: S
authors.lastname: Valente
authors.affiliation: Dipartimento di Scienze Medico-Chirurgiche, U.O.S. Oftalmologia, Università 'Sapienza' di Roma, Terracina, Italia.
authors.forename: E
authors.initials: E
authors.lastname: Gerace
authors.affiliation: Dipartimento di Scienze Medico-Chirurgiche, U.O.S. Oftalmologia, Università 'Sapienza' di Roma, Terracina, Italia.
authors.forename: P
authors.initials: P
authors.lastname: Trabucco
authors.affiliation: Departement D'Ophtalmologie, Hopital-Universitaire Gui De Chauliac, Montlellier, France.
authors.forename: S
authors.initials: S
authors.lastname: Navarre
authors.affiliation: Departement D'Ophtalmologie, Hopital-Universitaire Gui De Chauliac, Montlellier, France.
authors.forename: M
authors.initials: M
authors.lastname: Villain
authors.affiliation: Dipartimento di Scienze Medico-Chirurgiche, U.O.S. Oftalmologia, Università 'Sapienza' di Roma, Terracina, Italia.
authors.forename: E M
authors.initials: EM
authors.lastname: Vingolo
mesh_terms: D000208:Acute Disease; D000368:Aged; D002833:Choroiditis / Q000175:diagnosis* / Q000188:drug therapy*; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D000080364:Multifocal Choroiditis; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D011239:Prednisolone / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D012164:Retinal Diseases / Q000188:drug therapy* / Q000473:pathology*; D055213:Retinal Pigment Epithelium / Q000473:pathology*
chemical_list: D011239:Prednisolone; D011241:Prednisone
keywords: acute posterior multifocal placoid pigment epitheliopathy; fluorescein angiography; magnetic resonance imaging; optical coherence tomography