title: Early trends in invasive pneumococcal disease in children following the introduction of 13-valent pneumococcal conjugate vaccine: results from eight years of active surveillance in a Mexican hospital.
abstract: BACKGROUND
  In May 2012, universal vaccination with the 13-valent pneumococcal conjugate vaccine (PCV-13) was introduced for all children in the Tijuana region of Mexico, with a coverage of 80%.
  
  
  METHODS
  Between October 2005 and September 2013 active surveillance was undertaken for all invasive pneumococcal diseases (IPDs) in children admitted to the Tijuana General Hospital.
  
  
  RESULTS
  Following PCV-13 implementation, there was a 75% reduction in overall IPD, and no cases of serotype 19A, pneumococcal meningitis, and pneumococcal-associated deaths.
  
  
  CONCLUSIONS
  These results are the first to show the effectiveness of PCV-13 in Mexico.
authors.affiliation: Pediatric Infectious Diseases Service, Hospital General de Tijuana, Tijuana Baja-California, Paseo Centenario S/N, Zona Rio, Tijuana, Baja-California, ZC 22010, Mexico.
authors.forename: Enrigue
authors.initials: E
authors.lastname: Chacon-Cruz
authors.affiliation: Microbiology Laboratory, Hospital General de Tijuana, Tijuana Baja-California, Mexico.
authors.forename: R M
authors.initials: RM
authors.lastname: Rivas-Landeros
authors.affiliation: Microbiology Laboratory, Hospital General de Tijuana, Tijuana Baja-California, Mexico.
authors.forename: M L
authors.initials: ML
authors.lastname: Volker-Soberanes
keywords: mexico; pneumococcal diesase; pneumococcal vaccine; streptococcus pneumoniae; vaccine effectiveness