title: Recurrent pregnancy loss is associated with increased red cell distribution width and platelet distribution width.
abstract: OBJECTIVE
  The present study aims to evaluate how components of complete blood count are altered in women with a history of recurrent pregnancy loss.
  
  
  METHODS
  This was a retrospective evaluation of 60 women who had a history of recurrent pregnancy loss, 60 healthy women who had a first trimester pregnancy and 60 healthy parous women.
  
  
  RESULTS
  When compared with pregnant women and healthy controls, the women with a history of recurrent pregnancy loss had significantly higher red cell distribution width (RDW) and platelet distribution width (PDW) (P = 0.001 for both). Thrombophilia was detected in 31.7% of the women who had a history of recurrent pregnancy loss (19 out of 60). When compared to the women without thrombophilia, the women with thrombophilia had significantly lower body mass index (P = 0.034) but significantly higher RDW, PDW and plateletcrit (respectively, P = 0.043, P = 0.001 and P = 0.002). There were significant and positive correlations between RDW and PDW (r = 0.615, P = 0.001), RDW and plateletcrit (r = 0.343, P = 0.007) and PDW and plateletcrit (r = 0.340, P = 0.008) in women with a history of recurrent pregnancy loss.
  
  
  CONCLUSIONS
  An elevation in PDW and RDW values was found to be associated with recurrent pregnancy loss.
authors.affiliation: Department of Obstetrics and Gynecology, Haydarpasa Military Education and Research Hospital, GATA, Istanbul, Turkey.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Dundar
authors.forename: Mıne Kanat
authors.initials: MK
authors.lastname: Pektas
authors.forename: Serkan
authors.initials: S
authors.lastname: Bodur
authors.forename: Lale Vuslat
authors.initials: LV
authors.lastname: Bakır
authors.forename: Ahmet
authors.initials: A
authors.lastname: Cetin
mesh_terms: D000026:Abortion, Habitual / Q000097:blood*; D000293:Adolescent; D000328:Adult; D004909:Erythrocyte Indices; D005260:Female; D006801:Humans; D010976:Platelet Count; D011247:Pregnancy; D012189:Retrospective Studies; D019851:Thrombophilia / Q000097:blood / Q000150:complications*; D055815:Young Adult
keywords: platelet distribution width; recurrent pregnancy loss; red cell distribution width; thrombophilia