title: A case of Heyde syndrome: resolution following aortic valve replacement.
abstract: Heyde syndrome is a triad of aortic stenosis, acquired coagulopathy, and anemia due to bleeding from intestinal angiodysplasia. Here we describe a case of this syndrome. An 80-year-old woman with severe aortic stenosis was referred to our department for an aortic valve replacement. She suffered from recurrent iron-deficiency anemia and required transfusions every 2 weeks. Gastroscopy and colonoscopy were normal with the exception of angiodysplasia without bleeding in the cecum. After aortic valve replacement her anemia was resolved. She was discharged on postoperative day 22. No transfusions were needed after the procedure. To date, her hemoglobin has remained stable at >10 mg/dL.
authors.affiliation: Department of Cardiovascular Surgery, Hiroshima University Hospital, Hiroshima, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Taguchi
authors.affiliation: Department of Cardiovascular Surgery, Hiroshima University Hospital, Hiroshima, Japan.
authors.forename: Masazumi
authors.initials: M
authors.lastname: Watanabe
authors.affiliation: Department of Cardiovascular Surgery, Hiroshima University Hospital, Hiroshima, Japan.
authors.forename: Keisuke
authors.initials: K
authors.lastname: Watadani
authors.affiliation: Department of Cardiovascular Surgery, Hiroshima University Hospital, Hiroshima, Japan.
authors.forename: Keijiro
authors.initials: K
authors.lastname: Katayama
authors.affiliation: Department of Cardiovascular Surgery, Hiroshima University Hospital, Hiroshima, Japan.
authors.forename: Shinya
authors.initials: S
authors.lastname: Takahashi
authors.affiliation: Department of Cardiovascular Surgery, Hiroshima University Hospital, Hiroshima, Japan.
authors.forename: Taiichi
authors.initials: T
authors.lastname: Takasaki
authors.affiliation: Department of Cardiovascular Surgery, Hiroshima University Hospital, Hiroshima, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Kurosaki
authors.affiliation: Department of Cardiovascular Surgery, Hiroshima University Hospital, Hiroshima, Japan.
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Imai
authors.affiliation: Department of Cardiovascular Surgery, Hiroshima University Hospital, Hiroshima, Japan.
authors.forename: Taijiro
authors.initials: T
authors.lastname: Sueda
mesh_terms: D000369:Aged, 80 and over; D000740:Anemia / Q000473:pathology / Q000601:surgery*; D016888:Angiodysplasia / Q000473:pathology / Q000601:surgery*; D001021:Aortic Valve / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000473:pathology / Q000601:surgery*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000473:pathology / Q000601:surgery*; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D013577:Syndrome; D016896:Treatment Outcome; D056728:von Willebrand Disease, Type 2 / Q000473:pathology / Q000601:surgery*