title: [A case of Sagliker syndrome and literature review].
abstract: We analyzed the characters of Sagliker syndrome by reporting a case of Sagliker syndrome and reviewed literature. We found that Sagliker syndrome had low incidence rate, young onset age, and was more common in women. There were high levels of alkaline phosphatase and parathyroid hormone in the blood of the patients. Patients with Sagliker syndrome with primary onset of non-diabetic nephropathy usually had chronic glomerulonephritis. We thought that secondary hyperparathyroidism in patients with Sagliker syndrome was induced by parathyroid hyperplasia, but high levels of alkaline phosphatase and parathyroid hormone in the blood of the patients with the secondary hyperparathyroidism were the main cause of Sagliker syndrome. Parathyroidectomy could stop the progress of Sagliker syndrome, but it could not reverse the occurrence of skeletal malformation.
authors.affiliation: Department of Breast and THyroid Surgery, Third Xiangya Hospital, Central South University, Changsha 410013, China wuwei8912006@sina.com.
authors.forename: Wei
authors.initials: W
authors.lastname: Wu
authors.forename: Liyuan
authors.initials: L
authors.lastname: Qian
authors.forename: Xuedong
authors.initials: X
authors.lastname: Chen
authors.forename: Boni
authors.initials: B
authors.lastname: Ding
mesh_terms: D000469:Alkaline Phosphatase; D002908:Chronic Disease; D003928:Diabetic Nephropathies; D005260:Female; D006801:Humans; D006962:Hyperparathyroidism, Secondary; D016105:Parathyroidectomy; D013577:Syndrome
chemical_list: D000469:Alkaline Phosphatase