title: [Fibroblasts and lung fibrosis].
abstract: Fibroblasts are key cells in the fibrotic process. Their profibrotic phenotype is influenced by the environment in which they operate, both extracellular matrix and mediators which they are exposed. The pharmacologic modulation of the fibroblast phenotype allows to identify potential therapeutic targets which might interrupt the vicious cycle of pulmonary fibrogenesis.
authors.forename: Bruno
authors.initials: B
authors.lastname: Crestani
mesh_terms: D005109:Extracellular Matrix / Q000502:physiology; D005347:Fibroblasts / Q000473:pathology* / Q000502:physiology; D006801:Humans; D010641:Phenotype; D011658:Pulmonary Fibrosis / Q000209:etiology* / Q000473:pathology*