title: Psoriasis and obesity in French children: a case-control, multicentre study.
abstract: BACKGROUND
  Obesity is more common in adults with psoriasis than in the general population, but there is a lack of data available regarding this association in children.
  
  
  OBJECTIVE
  To evaluate whether obesity was more common in French children with psoriasis of any clinical type or severity.
  
  
  METHODS
  A multicentre case-control study was performed in 23 French dermatology centres. Children without chronic or genetic inflammatory disease were selected as controls and matched for age, sex and dermatology centre. We used three weight cut-off categories to compare the two groups: overweight, overweight with abdominal obesity and overweight with obesity according to the French Health Authority guidelines.
  
  
  RESULTS
  A total of 261 children with psoriasis were included. The mean age was 9.8 years, 126 were boys and 135 were girls. Overall, 42.5% of these children had plaque psoriasis and 32.2% had severe psoriasis. There was no difference between the psoriasis and control groups when the frequency of children who were overweight was compared (20·7% in psoriasis group vs. 17·1% in control group; P = 0·18). Overweight with abdominal obesity including obesity (18·4% vs. 10·4%; P = 0·009) and obesity alone (10·0% vs. 3·1%; P = 0·001) were more common in the psoriasis group.
  
  
  CONCLUSIONS
  This study shows that being overweight with abdominal obesity and being obese is more common in children with psoriasis than in controls. The risk factors are the same as those that affect the French general population, i.e. female sex and having a parent who was overweight. The severity and clinical type of psoriasis do not affect overweight and obesity.
authors.affiliation: Service de Dermatologie, Hôpital Victor Dupouy, 69 rue du Lieutenant-Colonel Prud'hon, 95100, Argenteuil, France.
authors.forename: E
authors.initials: E
authors.lastname: Mahé
authors.affiliation: Département de Santé Publique, Centre Hospitalier Universitaire Ambroise Paré, Université Versailles-Saint-Quentin-en-Yvelines, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.
authors.forename: A
authors.initials: A
authors.lastname: Beauchet
authors.affiliation: Service de Dermatologie, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université Paris-Descartes Sorbonne Paris Cité, Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Bodemer
authors.affiliation: Service de néphro-rhumato-dermatologie pédiatrique, Hôpital Femme-Mère-Enfant, 59, boulevard Pinel, 69500, Bron, France.
authors.forename: A
authors.initials: A
authors.lastname: Phan
authors.affiliation: Service de Dermatologie, Hôpital Brabois, 54000, Vandœuvre Les Nancy, France.
authors.forename: A-C
authors.initials: AC
authors.lastname: Bursztejn
authors.affiliation: Unité de Dermatologie Pédiatrique, Hôpital Pellegrin-Enfants, Bordeaux, France.
authors.forename: F
authors.initials: F
authors.lastname: Boralevi
authors.affiliation: Service de néphro-rhumato-dermatologie pédiatrique, Hôpital Femme-Mère-Enfant, 59, boulevard Pinel, 69500, Bron, France.
authors.forename: A-L
authors.initials: AL
authors.lastname: Souillet
authors.affiliation: Service de Dermatologie, Hôpital Archet 2, ESPIC CHU-Lenval, Nice, France.
authors.forename: C
authors.initials: C
authors.lastname: Chiaverini
authors.affiliation: Service de Pédiatrie Générale, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris, Paris, France.
authors.forename: E
authors.initials: E
authors.lastname: Bourrat
authors.affiliation: Service de Dermatologie, Centre Hospitalier Universitaire Pontchaillou, Rennes, France.|Service de Pédiatrie, Centre Hospitalier Universitaire Sud, Saint Pierre de la Réunion, France.
authors.forename: J
authors.initials: J
authors.lastname: Miquel
authors.affiliation: Service de Dermatologie, Centre Hospitalier Universitaire Hôpital du Bocage, Dijon, France.
authors.forename: P
authors.initials: P
authors.lastname: Vabres
authors.affiliation: Service de Dermatologie, Hôtel Dieu, Nantes, France.
authors.forename: S
authors.initials: S
authors.lastname: Barbarot
authors.affiliation: Service de Dermatologie, Centre Hospitalier Saint Eloi, Montpellier, France.
authors.forename: D
authors.initials: D
authors.lastname: Bessis
authors.affiliation: Service de Dermatologie, Hôpital Robert Debré, Reims, France.
authors.forename: C
authors.initials: C
authors.lastname: Eschard
authors.affiliation: Service de Dermatologie, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université Paris-Descartes Sorbonne Paris Cité, Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Hadj-Rabia
mesh_terms: D000208:Acute Disease; D016022:Case-Control Studies; D002648:Child; D002908:Chronic Disease; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D056128:Obesity, Abdominal / Q000150:complications / Q000453:epidemiology / Q000235:genetics; D063766:Pediatric Obesity / Q000150:complications* / Q000453:epidemiology / Q000235:genetics; D010375:Pedigree; D011565:Psoriasis / Q000150:complications* / Q000453:epidemiology / Q000235:genetics