title: Palladium-catalyzed selective aminoamidation and aminocyanation of alkenes using isonitrile as amide and cyanide sources.
abstract: A mild and efficient palladium-catalyzed intermolecular aminoamidation and aminocyanation reaction of alkenes with a broad substrate scope has been developed. This cyclization process provides a valuable synthetic tool for obtaining substituted indolines, tetrahydroisoquinolines and pyrrolidines in good to excellent yields.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China. jianghf@scut.edu.cn.
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang
authors.forename: Hanling
authors.initials: H
authors.lastname: Gao
authors.forename: Bifu
authors.initials: B
authors.lastname: Liu
authors.forename: Wanqing
authors.initials: W
authors.lastname: Wu
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D003486:Cyanides / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis*; D010165:Palladium / Q000737:chemistry; D011759:Pyrrolidines / Q000138:chemical synthesis*; D044005:Tetrahydroisoquinolines / Q000138:chemical synthesis*
chemical_list: D000475:Alkenes; D000577:Amides; D003486:Cyanides; D007211:Indoles; D011759:Pyrrolidines; D044005:Tetrahydroisoquinolines; D010165:Palladium