title: [Hypercoagulability in a patient with meningioma and Factor VLeiden mutation].
abstract: A 63-year-old woman with meningioma was admitted for surgery. Preoperatively she presented with a clinical state of hypercoagulability in the large central veins visualised by ultrasound. She had no previous history of thrombosis. Surgery was postponed and by biochemical evaluation only Factor VLeiden heterozygosity was found. Weeks later the patient was readmitted for surgery. No bleeding or thrombotic complications were experienced during the operation. The observed condition might be a result of a combination of the Factor VLeiden mutation and her meningioma. Meningioma itself has not been described as a risk factor of venous thrombosis.
authors.affiliation: Afdeling for Klinisk Biokemi og Farmakologi, Odense Universitetshospital, Sdr. Boulevard 29, 5000 Odense C. charlotte.gils@rsyd.dk.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Gils
authors.forename: Christina
authors.initials: C
authors.lastname: Frøslev-Friis
mesh_terms: D005165:Factor V / Q000235:genetics*; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000150:complications* / Q000601:surgery; D008579:Meningioma / Q000150:complications* / Q000601:surgery; D008875:Middle Aged; D017354:Point Mutation; D019851:Thrombophilia / Q000000981:diagnostic imaging / Q000209:etiology*; D014463:Ultrasonography
chemical_list: C095381:factor V Leiden; D005165:Factor V