title: The relationship between fragmented QRS complexes and SYNTAX and Gensini scores in patients with acute coronary syndrome.
abstract: BACKGROUND
  Fragmented QRS (fQRS) complexes on 12-lead electrocardiography (ECG) have been reported to be predictors of cardiac events and all-cause mortality in coronary artery disease (CAD).
  
  
  OBJECTIVE
  To investigate the relationship between fQRS complexes and SYNTAX and Gensini scores in patients with acute coronary syndrome (ACS).
  
  
  METHODS
  A total of 302 patients (223 men and 79 women) with ACS (133 ST elevated myocardial infarction [STEMI], 107 non-STEMI [NSTEMI], and 62 unstable angina pectoris [USAP]) were evaluated retrospectively in this study. An fQRS pattern was found in 70 patients (fQRS group) but was not found in 232 patients (non-fQRS group). SYNTAX score > 22 and Gensini score > 20 were defined as high SYNTAX and Gensini scores. The relationship between the presence of fQRS on 12-lead ECG and SYNTAX and Gensini scores was assessed.
  
  
  RESULTS
  SYNTAX score (p < 0.001), Gensini score (p < 0.001), NYHA class (p < 0.001), QRS duration (p < 0.001), number of disease vessels (p = 0.003), and high sensitive troponin T levels (p = 0.026) were significantly higher in the fQRS group. The number of fQRS leads (HR 5.79, 95% CI 2.78-12.06, p < 0.001, HR 3.41, 95% CI 1.32-8.78, p = 0.016, respectively) was found to be an independent predictor of high SYNTAX score and high Gensini score in multivariate analysis.
  
  
  CONCLUSIONS
  The number of fQRS leads on 12-lead ECG on admission is associated with the severity and complexity of CAD in patients with ACS.
authors.affiliation: Department of Cardiology, Canakkale Onsekiz Mart University, School of Medicine, Canakkale, Turkey. adembekler27@gmail.com.
authors.forename: Adem
authors.initials: A
authors.lastname: Bekler
authors.forename: Ahmet
authors.initials: A
authors.lastname: Barutçu
authors.forename: Erhan
authors.initials: E
authors.lastname: Tenekecioglu
authors.forename: Burak
authors.initials: B
authors.lastname: Altun
authors.forename: Emine
authors.initials: E
authors.lastname: Gazi
authors.forename: Ahmet
authors.initials: A
authors.lastname: Temiz
authors.forename: Bahadır
authors.initials: B
authors.lastname: Kırılmaz
authors.forename: Muhammed Turgut Alper
authors.initials: MT
authors.lastname: Ozkan
authors.forename: Ali Umit
authors.initials: AU
authors.lastname: Yener
mesh_terms: D054058:Acute Coronary Syndrome / Q000175:diagnosis*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000789:Angina, Unstable / Q000175:diagnosis; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D000072658:Non-ST Elevated Myocardial Infarction / Q000175:diagnosis; D012189:Retrospective Studies; D000072657:ST Elevation Myocardial Infarction / Q000175:diagnosis; D012720:Severity of Illness Index; D055815:Young Adult