title: Assessing the value of bilateral inferior petrosal sinus sampling in the diagnosis and treatment of a complex case of Cushing's disease.
abstract: A 41-year-old female visited Ruijin Hospital because her face was swollen for more than 2 months. The patient was initially diagnosed with Cushing's disease (CD). Several examinations, including a dexamethasone suppression test (DST) at 2 mg and 8 mg, pituitary MRI, abdominal CT, punch biopsy of adrenal masses, and bilateral inferior petrosal sinus sampling (BIPSS), were performed, but the findings were not consistent with the clinical presentation. Ultimately, the patient underwent surgery and recovered. In this case, BIPSS was a useful way to diagnosis CD and suggested the exact location of a pituitary adenoma to Neurosurgery. BIPSS should be a required test for cases of CD that cannot be definitively diagnosed with just an MRI and 8 mg DST before surgery.
authors.affiliation: Department of Neurology, Wuxi No.3 People's Hospital, Wuxi, China.
authors.forename: Changyan
authors.initials: C
authors.lastname: Fan
authors.affiliation: Department of Neurosurgery, Shanghai Institute of Neurosurgery, Shanghai Changzheng Hospital, Shanghai, China.
authors.forename: Chenran
authors.initials: C
authors.lastname: Zhang
authors.affiliation: Department of Neurosurgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Xiuhua
authors.initials: X
authors.lastname: Shi
authors.affiliation: Department of Neurosurgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Liuguan
authors.initials: L
authors.lastname: Bian
authors.affiliation: Department of Neurosurgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Weiguo
authors.initials: W
authors.lastname: Zhao
authors.affiliation: Department of Radiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Department of Endocrine and Metabolic Disorders, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Tingwei
authors.initials: T
authors.lastname: Su
authors.affiliation: Department of Endocrine and Metabolic Disorders, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Weiqing
authors.initials: W
authors.lastname: Wang
authors.affiliation: Department of Endocrine and Metabolic Disorders, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Xiaoying
authors.initials: X
authors.lastname: Li
authors.affiliation: Department of Endocrine and Metabolic Disorders, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Guang
authors.initials: G
authors.lastname: Ning
authors.affiliation: Department of Neurology, Wuxi No.3 People's Hospital, Wuxi, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Kong
authors.affiliation: Department of Neurology, Wuxi No.3 People's Hospital, Wuxi, China.
authors.forename: Lingling
authors.initials: L
authors.lastname: Hu
authors.affiliation: Department of Neurosurgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Qingfang
authors.initials: Q
authors.lastname: Sun
keywords: Cushing's disease; Cushing's syndrome; bilateral inferior petrosal sinus sampling (BIPSS)