title: [Toxic nephropathy secondary to occupational exposure to metallic mercury].
abstract: Toxic nephrophaties secondary to occupational exposure to metals have been widely studied, including membranous nephropathy by mercury, which is rare. Occupational poisoning by mercury is frequent, neurological symptoms are the main form of clinical presentation. Secondary renal involvement in chronic exposure to metallic mercury can cause glomerular disease by deposit of immune-complexes. Membranous glomerulopathy and minimal change disease are the most frequently reported forms. Here we describe the case of a patient with occupational exposure to metallic mercury, where nephrotic syndrome due to membranous glomerulonephritis responded favorably to both chelation and immunosuppressive therapy.
authors.affiliation: Servicio de Toxicología, Hospital Nacional Profesor Doctor Alejandro Posadas, Buenos Aires, Argentina. E-mail: avoitzuk@yahoo.com.ar.
authors.forename: Ana
authors.initials: A
authors.lastname: Voitzuk
authors.forename: Vanina
authors.initials: V
authors.lastname: Greco
authors.forename: Daniel
authors.initials: D
authors.lastname: Caputo
authors.forename: Estela
authors.initials: E
authors.lastname: Alvarez
mesh_terms: D000328:Adult; D015913:Chelation Therapy; D015433:Glomerulonephritis, Membranous / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008628:Mercury / Q000633:toxicity*; D009404:Nephrotic Syndrome / Q000209:etiology / Q000628:therapy; D016273:Occupational Exposure / Q000009:adverse effects*
chemical_list: D007166:Immunosuppressive Agents; D008628:Mercury
keywords: D-penicillamine; glomerulonephritis; metallic mercury