title: Tunable spin-selective transport through DNA with mismatched base pairs.
abstract: In our theoretical analysis of spin-selective transport through a homogeneous poly(G)-poly(C) DNA we explore the influence of a mismatched base pair in the DNA chain. The spin polarization of the electrical current through DNA is strongly sensitive to the presence of the mispair in a DNA with less than 20 base pairs. Replacing a canonical G-C base pair by a G-A mispair in homogeneous DNA can strongly decrease, increase up to an order of magnitude, or even change the sign of spin polarization of the electrical current. The mispair induced spin-selective current through DNA also depends on the location of the mispair within the DNA.
authors.affiliation: Department of Physics and Astronomy, Georgia State University, Atlanta, Georgia 30303, USA.
authors.forename: Vadym M
authors.initials: VM
authors.lastname: Apalkov
authors.forename: Tapash
authors.initials: T
authors.lastname: Chakraborty
mesh_terms: D020137:Base Pair Mismatch; D020029:Base Pairing; D004247:DNA / Q000737:chemistry* / Q000235:genetics*; D004553:Electric Conductivity; D004579:Electron Transport; D004581:Electronics / Q000379:methods*; D060328:Magnetic Phenomena; D013696:Temperature
chemical_list: D004247:DNA