title: [Immediate and long-term effects of posthypoxic myocardial ischemia in newborns].
abstract: The aim of the research was to study heart adaptation to hypoxia in infants in the early neonatal period and the dynamics of their development catamnesis of 294 infants who underwent hypoxia in the perinatal period was examined. Strain index is used as a prognostic criterion of cardiovascular disorders, which characterizes the activity index of independent contour and coefficient of myoglobin. Intensity of cardiovascular disorders in infants in the early neonatal period depended on the length and severity of hypoxia. Follow-up data revealed various outcomes posthypoxic myocardial ischemia. In most cases, there is a benign outcome in recovery, but in 37% of cases developed posthypoxic cardiomyopathy. Long-term consequences of posthypoxic myocardial more pronounced in severe cardiomyopathy in 16.7% posthypoxic cardiomyopathy transformed into dilated cardiomyopathy, accompanied by life-threatening arrhythmias and heart failure.The immediate forecast and remote consequence of posthypoxic myocardial ischemia depends on the degree of hypoxic myocardial injury, timely adjuvant therapy.
mesh_terms: D002311:Cardiomyopathy, Dilated / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D005311:Fetal Hypoxia / Q000150:complications* / Q000503:physiopathology; D006333:Heart Failure / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D017202:Myocardial Ischemia / Q000209:etiology / Q000503:physiopathology*; D009211:Myoglobin / Q000378:metabolism; D011247:Pregnancy
chemical_list: D009211:Myoglobin