title: [Specific antibody deficiency: cases serie].
abstract: Specific antibody deficiency is a common antibody immunodeficiency defined as a poor antibody response to pneumococcal polysaccharides antigens present in the 23-valent pneumococcal vaccine, with normal immunoglobulins and normal response to protein antigens. Clinical manifestations include recurrent sinopulmonary infections, severe infections and asthma. The aim of this presentation is to describe clinical manifestations and evolution of a cohort of children with specific antibody deficiency diagnosed and followed in our center between 1998 and 2012.
authors.affiliation: Unidad de Inmunología, Hospital de Niños Sor María Ludovica.
authors.forename: Diana
authors.initials: D
authors.lastname: Cabanillas
authors.affiliation: Servicio de Neumonología, Hospital de Niños Sor María Ludovica, La Plata.
authors.forename: Virginia
authors.initials: V
authors.lastname: D'Alessandro
authors.affiliation: Unidad de Inmunología, Hospital de Niños Sor María Ludovica.
authors.forename: Graciela
authors.initials: G
authors.lastname: Diez
authors.affiliation: Unidad de Inmunología, Hospital de Niños Sor María Ludovica.
authors.forename: Lorena
authors.initials: L
authors.lastname: Regairaz
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000175:diagnosis*; D007223:Infant; D008297:Male; D011135:Polysaccharides, Bacterial / Q000276:immunology*
chemical_list: D011135:Polysaccharides, Bacterial