title: Lung cancer incidence trends by histology type among Asian American, Native Hawaiian, and Pacific Islander populations in the United States, 1990-2010.
abstract: BACKGROUND
  Lung cancer is one of the leading cancer sites diagnosed among Asian Americans, Pacific Islanders, and Native Hawaiians (AANHPI). To better understand the patterns of lung cancer incidence among AANHPIs, we examined the incidence trends of five histologic cell types of lung cancer across ten AANHPI populations in comparison with non-Hispanic Whites.
  
  
  METHODS
  Lung cancer incidence data from 1990 through 2010 were obtained from 13 U.S. population-based cancer registries. Age-adjusted histologic cell-type-specific incidence rates and 95% confidence intervals were calculated. Joinpoint regression models and annual percentage change (APC) statistics were used to characterize the magnitude and direction of trends.
  
  
  RESULTS
  From 1990 through 2010, incidence rates of adenocarcinoma increased significantly for Filipino and Korean women with a 2.6% and 3.0% annual percentage increase, respectively. More recently, a significant rise in the incidence of adenocarcinoma was observed for Chinese men (1996-2010; APC = 1.3%). Squamous cell carcinoma (SCC) increased 2.4% per year among Japanese women. For SCC, small cell lung carcinoma, large cell and other specified carcinoma, and unspecified types, stable or decreasing trends were observed in most AANHPI groups and non-Hispanic Whites.
  
  
  CONCLUSIONS
  AANHPIs demonstrate a range in the burden of lung cancer across histologies and specific populations.
  
  
  CONCLUSIONS
  These findings illustrate the importance of disaggregating AANHPIs into their specific populations. The rise in incidence of adenocarcinoma and SCC among certain AANHPIs demonstrates the need for research into non-tobacco associated risk factors for these populations and targeted efforts for tobacco prevention.
authors.affiliation: Cancer Prevention Institute of California, Fremont, California. Stanford Cancer Institute, Stanford, California. iona.cheng@cpic.org.
authors.forename: Iona
authors.initials: I
authors.lastname: Cheng
authors.affiliation: Cancer Prevention Institute of California, Fremont, California. Stanford Cancer Institute, Stanford, California. Division of Epidemiology, Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California.
authors.forename: Gem M
authors.initials: GM
authors.lastname: Le
authors.affiliation: Surveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland.
authors.forename: Anne-Michelle
authors.initials: AM
authors.lastname: Noone
authors.affiliation: Social Cognitive Sciences Graduate Group, School of Social Sciences Humanities and Arts, University of California, Merced, California.
authors.forename: Kathleen
authors.initials: K
authors.lastname: Gali
authors.affiliation: Division of Epidemiology, Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California. Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, California.
authors.forename: Manali
authors.initials: M
authors.lastname: Patel
authors.affiliation: Stanford Cancer Institute, Stanford, California. Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, California.
authors.forename: Robert W
authors.initials: RW
authors.lastname: Haile
authors.affiliation: Stanford Cancer Institute, Stanford, California. Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, California.
authors.forename: Heather A
authors.initials: HA
authors.lastname: Wakelee
authors.affiliation: Cancer Prevention Institute of California, Fremont, California. Stanford Cancer Institute, Stanford, California. Division of Epidemiology, Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California.
authors.forename: Scarlett L
authors.initials: SL
authors.lastname: Gomez
mesh_terms: D000230:Adenocarcinoma / Q000208:ethnology*; D000368:Aged; D000369:Aged, 80 and over; D001208:Asia / Q000208:ethnology; D001213:Asian / Q000706:statistics & numerical data*; D018287:Carcinoma, Large Cell / Q000208:ethnology*; D002294:Carcinoma, Squamous Cell / Q000208:ethnology*; D005260:Female; D006254:Hawaii / Q000208:ethnology; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000208:ethnology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D044468:Native Hawaiian or Pacific Islander / Q000706:statistics & numerical data*; D018426:SEER Program; D012737:Sex Factors; D055752:Small Cell Lung Carcinoma / Q000208:ethnology*; D014481:United States / Q000453:epidemiology; D044465:White People / Q000706:statistics & numerical data