title: Simultaneous detection of herpes simplex virus 1 and 2 in the cerebrospinal fluid of a patient with seizures and encephalitis.
abstract: We report a case of a 62-year-old female with seizures and encephalitis. Molecular testing of the patient's cerebrospinal fluid was positive for both herpes simplex virus 1 and 2 (HSV-1 and HSV-2). To our knowledge, this is the first report of simultaneous detection of HSV-1 and HSV-2 in cerebrospinal fluid.
authors.affiliation: Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: Neil W
authors.initials: NW
authors.lastname: Anderson
authors.affiliation: Division of Infectious Diseases, Mercy Clinic, Springfield, Missouri, USA.
authors.forename: William
authors.initials: W
authors.lastname: Sistrunk
authors.affiliation: Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA binnicker.matthew@mayo.edu.
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Binnicker
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D004279:DNA, Viral / Q000134:cerebrospinal fluid*; D004660:Encephalitis; D005260:Female; D006561:Herpes Simplex / Q000134:cerebrospinal fluid / Q000150:complications / Q000821:virology; D018259:Herpesvirus 1, Human / Q000235:genetics*; D018258:Herpesvirus 2, Human / Q000235:genetics*; D006801:Humans; D008875:Middle Aged; D012640:Seizures
chemical_list: D000998:Antiviral Agents; D004279:DNA, Viral; D000212:Acyclovir