title: A co-operative Ni-Cu system for Csp-Csp and Csp-Csp(2) cross-coupling providing a direct access to unsymmetrical 1,3-diynes and en-ynes.
abstract: An efficient cross-coupling of alkynes with alkynyl and alkenyl halides catalysed by a Ni-Cu system without any ligand has been achieved. The reaction is suggested to proceed by Ni(0) catalysis assisted by Cu(I). A series of functionalised diaryl, aryl-alkyl, aryl-heteroaryl, diheteroaryl 1,3-di-ynes and en-ynes are obtained in high yields.
authors.affiliation: Department of Organic Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India. ocbcr@iacs.res.in.
authors.forename: Nirmalya
authors.initials: N
authors.lastname: Mukherjee
authors.forename: Debasish
authors.initials: D
authors.lastname: Kundu
authors.forename: Brindaban C
authors.initials: BC
authors.lastname: Ranu
mesh_terms: D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D053280:Diynes / Q000737:chemistry*; D007536:Isomerism; D009532:Nickel / Q000737:chemistry*; D011789:Quantum Theory
chemical_list: D053280:Diynes; D002244:Carbon; D003300:Copper; D009532:Nickel