title: Overview of research on Bombyx mori microRNA.
abstract: MicroRNAs (miRNAs) constitute some of the most significant regulatory factors involved at the post-transcriptional level after gene expression, contributing to the modulation of a large number of physiological processes such as development, metabolism, and disease occurrence. This review comprehensively and retrospectively explores the literature investigating silkworm, Bombyx mori L. (Lepidoptera: Bombicidae), miRNAs published to date, including discovery, identification, expression profiling analysis, target gene prediction, and the functional analysis of both miRNAs and their targets. It may provide experimental considerations and approaches for future study of miRNAs and benefit elucidation of the mechanisms of miRNAs involved in silkworm developmental processes and intracellular activities of other unknown non-coding RNAs.
authors.affiliation: Key Laboratory of Silkworm and Mulberry Genetic Improvement, Ministry of Agriculture, Jiangsu University of Science and Technology, Zhenjiang City 212018 Jiangsu Province, People's Republic of China wang7xin23@yeah.net.
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.affiliation: Key Laboratory of Silkworm and Mulberry Genetic Improvement, Ministry of Agriculture, Jiangsu University of Science and Technology, Zhenjiang City 212018 Jiangsu Province, People's Republic of China tangshunming2002@163.com.
authors.forename: Shun-ming
authors.initials: SM
authors.lastname: Tang
authors.affiliation: Key Laboratory of Silkworm and Mulberry Genetic Improvement, Ministry of Agriculture, Jiangsu University of Science and Technology, Zhenjiang City 212018 Jiangsu Province, People's Republic of China shenxjsri@163.com.
authors.forename: Xing-jia
authors.initials: XJ
authors.lastname: Shen
mesh_terms: D000818:Animals; D012831:Bombyx / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D035683:MicroRNAs
chemical_list: D035683:MicroRNAs
keywords: expression profiling analysis; microarray technology; prediction; review; silkworm; target gene