title: Oligopeptide-heavy metal interaction monitoring by hybrid gold nanoparticle based assay.
abstract: Phytochelatins are small peptides that can be found in several organisms, which use these oligopeptides to handle heavy metal elements. Here, we report a method for monitoring interactions between lead(ii) ions in aqueous solutions and phytochelatin 6 oligopeptide bioconjugated onto pegylated gold nanorods (PEG-AuNrs). This study is the first step towards a high sensitive label free optical biosensor to quantify heavy metal pollution in water.
authors.affiliation: Institute for Microelectronics and Microsystems, Unit of Naples-National Research Council, Via P. Castellino 111, 80127, Italy.
authors.forename: Jane
authors.initials: J
authors.lastname: Politi
authors.forename: Jolanda
authors.initials: J
authors.lastname: Spadavecchia
authors.forename: Mario
authors.initials: M
authors.lastname: Iodice
authors.forename: Luca
authors.initials: L
authors.lastname: de Stefano
mesh_terms: D015374:Biosensing Techniques; D006046:Gold / Q000737:chemistry*; D007854:Lead / Q000032:analysis*; D053768:Metal Nanoparticles / Q000737:chemistry*; D009842:Oligopeptides / Q000737:chemistry*
chemical_list: D009842:Oligopeptides; D007854:Lead; D006046:Gold