title: Periocular intralymphatic histiocytosis or localized Melkersson-Rosenthal syndrome?
abstract: We describe three cases of periocular edema with histopathologic features of intralymphatic histiocytosis without extravascular granulomas. All were elderly males with no other significant medical problems. Previous reports of periocular Melkersson-Rosenthal syndrome are identical clinically, and some reports show illustrations of intralymphatic histiocytosis histopathologically, in addition to other features typical of the syndrome. Given the lack of associated diseases or other features of the Melkersson-Rosenthal triad, some of these cases may be better defined as periocular intralymphatic histiocytosis.
authors.affiliation: University of Auckland, Auckland, New Zealand; Diagnostic Medlab, Ellerslie, Auckland, New Zealand.
authors.forename: Patrick O
authors.initials: PO
authors.lastname: Emanuel
authors.forename: Isabelle
authors.initials: I
authors.lastname: Lewis
authors.forename: Brent
authors.initials: B
authors.lastname: Gaskin
authors.forename: Paul
authors.initials: P
authors.lastname: Rosser
authors.forename: Neville
authors.initials: N
authors.lastname: Angelo
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D005141:Eyelid Diseases / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D006644:Histiocytes / Q000473:pathology; D015614:Histiocytosis / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008208:Lymphatic System / Q000473:pathology; D008297:Male; D008556:Melkersson-Rosenthal Syndrome / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged
keywords: Melkersson-Rosenthal syndrome; histiocytes; intravascular; lymphatic; periocular