title: Acromegaly: an endocrine society clinical practice guideline.
abstract: OBJECTIVE
  The aim was to formulate clinical practice guidelines for acromegaly.
  
  
  METHODS
  The Task Force included a chair selected by the Endocrine Society Clinical Guidelines Subcommittee (CGS), five experts in the field, and a methodologist. The authors received no corporate funding or remuneration. This guideline is cosponsored by the European Society of Endocrinology.
  
  
  METHODS
  This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe both the strength of recommendations and the quality of evidence. The Task Force reviewed primary evidence and commissioned two additional systematic reviews.
  
  
  METHODS
  One group meeting, several conference calls, and e-mail communications enabled consensus. Committees and members of the Endocrine Society and the European Society of Endocrinology reviewed drafts of the guidelines.
  
  
  CONCLUSIONS
  Using an evidence-based approach, this acromegaly guideline addresses important clinical issues regarding the evaluation and management of acromegaly, including the appropriate biochemical assessment, a therapeutic algorithm, including use of medical monotherapy or combination therapy, and management during pregnancy.
authors.affiliation: Stanford University School of Medicine (L.K.), Stanford, California 94305; Brigham and Women's Hospital (E.R.L), Boston, Massachusetts 02115; Cedars-Sinai Medical Center (S.M.), Los Angeles, California 90048; Northwestern University Feinberg School of Medicine (M.E.M), Chicago, Illinois 60611; Mayo Clinic (M.H.M.), Rochester, Minnesota 55905; Vanderbilt University (A.U.), Nashville, Tennessee 37232; and Oxford Centre Diabetes, Endocrinology, and Metabolism (J.A.H.W.), Churchill Hospital, Oxfordshire OX3 7RP, United Kingdom.
authors.forename: Laurence
authors.initials: L
authors.lastname: Katznelson
authors.forename: Edward R
authors.initials: ER
authors.lastname: Laws
authors.forename: Shlomo
authors.initials: S
authors.lastname: Melmed
authors.forename: Mark E
authors.initials: ME
authors.lastname: Molitch
authors.forename: Mohammad Hassan
authors.initials: MH
authors.lastname: Murad
authors.forename: Andrea
authors.initials: A
authors.lastname: Utz
authors.forename: John A H
authors.initials: JA
authors.lastname: Wass
mesh_terms: D000172:Acromegaly / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D004704:Endocrinology / Q000592:standards; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy