title: Development of a computerized tool for the chinese version of the montreal cognitive assessment for screening mild cognitive impairment.
abstract: BACKGROUND
  The Montreal Cognitive Assessment (MoCA) is used for screening mild cognitive impairment (MCI), and the Beijing version (MoCA-BJ) is widely used in China. We aimed to develop a computerized tool for MoCA-BJ (MoCA-CC).
  
  
  METHODS
  MoCA-CC used person-machine interaction instead of patient-to-physician interaction; other aspects such as the scoring system did not differ from the original test. MoCA-CC, MoCA-BJ and routine neuropsychological tests were administered to 181 elderly participants (MCI = 96, normal controls [NC] = 85).
  
  
  RESULTS
  A total of 176 (97.24%) participants were evaluated successfully by MoCA-CC. Cronbach's α for MoCA-CC was 0.72. The test-retest reliability (retesting after six weeks) was good (intraclass correlation coefficient = 0.82;P< 0.001). Significant differences were observed in total scores (t= 9.38,P< 0.001) and individual item scores (t= 2.18-8.62,P< 0.05) between the NC and MCI groups, except for the score for "Naming" (t= 0.24,P= 0.81). The MoCA-CC total scores were highly correlated with the MoCA-BJ total scores (r= 0.93,P< 0.001) in the MCI participants. The area under receiver-operator curve for the prediction of MCI was 0.97 (95% confidence interval = 0.95-1.00). At the optimal cut-off score of 25/26, MoCA-CC demonstrated 95.8% sensitivity and 87.1% specificity.
  
  
  CONCLUSIONS
  The MoCA-CC tool developed here has several advantages over the paper-pencil method and is reliable for screening MCI in elderly Chinese individuals, especially in the primary clinical setting. It needs to be validated in other diverse and larger populations.
authors.affiliation: Department of Neurology, Chengdu Military General Hospital, No270, Rongdu Avenue, Jinniu District, Chengdu 610083, Sichuan, China.
authors.forename: Ke
authors.initials: K
authors.lastname: Yu
authors.affiliation: Department of Rehabilitation, Wuhan General Hospital of Guangzhou Military Command, Wuhan 430070, Hubei, China.
authors.forename: Shangang
authors.initials: S
authors.lastname: Zhang
authors.affiliation: Department of Neurology, Chengdu Military General Hospital, No270, Rongdu Avenue, Jinniu District, Chengdu 610083, Sichuan, China.
authors.forename: Qingsong
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Computer Networking Center, Chengdu Military General Hospital, Chengdu 610083, Sichuan, China.
authors.forename: Xiaofei
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Geriatrics, Chengdu Military General Hospital, Chengdu 610083, Sichuan, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Qin
authors.affiliation: Department of Neurology, Chengdu Military General Hospital, No270, Rongdu Avenue, Jinniu District, Chengdu 610083, Sichuan, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Psychiatry, Chengdu Military General Hospital, Chengdu 610083, Sichuan, China.
authors.forename: Congyang
authors.initials: C
authors.lastname: Li
authors.affiliation: Department of Neurology, Chengdu Military General Hospital, No270, Rongdu Avenue, Jinniu District, Chengdu 610083, Sichuan, China.
authors.forename: Yuxian
authors.initials: Y
authors.lastname: Wu
authors.affiliation: Department of Neurology, Chengdu Military General Hospital, No270, Rongdu Avenue, Jinniu District, Chengdu 610083, Sichuan, China.
authors.forename: Weiwen
authors.initials: W
authors.lastname: Wang
authors.affiliation: Department of Neurology, Chengdu Military General Hospital, No270, Rongdu Avenue, Jinniu District, Chengdu 610083, Sichuan, China.
authors.forename: Hang
authors.initials: H
authors.lastname: Lin
keywords: cognitive screening; computer; elderly; mild cognitive impairment; montreal cognitive assessment