title: [Basic biological roles of galectins in tissue repair and tumor growth].
abstract: Galectins are representatives of endogenous lectins - molecules specifically recognizing distinct sugar motifs. They play an important role in the processes of cell proliferation, differentiation, migration and extracellular matrix formation. Furthermore, galectins are able to transfer cellular signals and to participate in intercellular interaction. It has been proven that galectins play an important role in the formation of tumor and/or wound healing microenvironment. This review contains an overview of experimental and clinical studies dealing with biological roles of galectins in tissue repair and in its parallel - the tumor growth.
authors.forename: Peter
authors.initials: P
authors.lastname: Gál
authors.forename: Lenka
authors.initials: L
authors.lastname: Varinská
authors.forename: Vlasta
authors.initials: V
authors.lastname: Peržeľová
authors.forename: Ján
authors.initials: J
authors.lastname: Jakubčo
authors.forename: Martina
authors.initials: M
authors.lastname: Kostelníková
authors.forename: Ivan
authors.initials: I
authors.lastname: Kováč
authors.forename: Peter
authors.initials: P
authors.lastname: Spurný
authors.forename: Karel
authors.initials: K
authors.lastname: Smetana
mesh_terms: D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D018450:Disease Progression; D005109:Extracellular Matrix / Q000473:pathology / Q000502:physiology; D037161:Galectins / Q000502:physiology*; D006801:Humans; D009369:Neoplasms / Q000473:pathology / Q000503:physiopathology*; D014945:Wound Healing / Q000502:physiology*
chemical_list: D037161:Galectins