title: Safety and efficacy of therapies for skin symptoms of psoriasis in patients with psoriatic arthritis: a systematic review.
abstract: Numerous guidelines and recommendations exist for the treatment of psoriasis in various populations. One important population is patients with psoriatic arthritis (PsA) who have symptoms of both joint and skin disease. In patients with both facets of psoriatic disease, skin and joints must be treated separately, but also simultaneously. As several systemic therapies are approved for either one or both, the concept of treating both facets with the same drug is feasible. This review summarizes evidence from studies in patients with PsA on the efficacy of these drugs on psoriatic skin disease in these patients.
authors.affiliation: From the Department of Dermatology, Geneva University Hospital, Geneva, Switzerland; Ameriderm Research, Ormond Beach, Florida; University of Central Florida College of Medicine, Orlando, Florida; University of Illinois College of Medicine, Urbana, Illinois; and Tufts Medical Center, Boston, Massachusetts, USA.W-H. Boehncke, MD; D. Alvarez Martinez, BS, Department of Dermatology, Geneva University Hospital; J.A. Solomon, MD, PhD, Ameriderm Research, University of Central Florida College of Medicine, University of Illinois College of Medicine; A.B. Gottlieb, MD, PhD, Tufts Medical Center. wolf-henning.boehncke@hcuge.ch.
authors.forename: Wolf-Henning
authors.initials: WH
authors.lastname: Boehncke
authors.affiliation: From the Department of Dermatology, Geneva University Hospital, Geneva, Switzerland; Ameriderm Research, Ormond Beach, Florida; University of Central Florida College of Medicine, Orlando, Florida; University of Illinois College of Medicine, Urbana, Illinois; and Tufts Medical Center, Boston, Massachusetts, USA.W-H. Boehncke, MD; D. Alvarez Martinez, BS, Department of Dermatology, Geneva University Hospital; J.A. Solomon, MD, PhD, Ameriderm Research, University of Central Florida College of Medicine, University of Illinois College of Medicine; A.B. Gottlieb, MD, PhD, Tufts Medical Center.
authors.forename: David
authors.initials: D
authors.lastname: Alvarez Martinez
authors.affiliation: From the Department of Dermatology, Geneva University Hospital, Geneva, Switzerland; Ameriderm Research, Ormond Beach, Florida; University of Central Florida College of Medicine, Orlando, Florida; University of Illinois College of Medicine, Urbana, Illinois; and Tufts Medical Center, Boston, Massachusetts, USA.W-H. Boehncke, MD; D. Alvarez Martinez, BS, Department of Dermatology, Geneva University Hospital; J.A. Solomon, MD, PhD, Ameriderm Research, University of Central Florida College of Medicine, University of Illinois College of Medicine; A.B. Gottlieb, MD, PhD, Tufts Medical Center.
authors.forename: James A
authors.initials: JA
authors.lastname: Solomon
authors.affiliation: From the Department of Dermatology, Geneva University Hospital, Geneva, Switzerland; Ameriderm Research, Ormond Beach, Florida; University of Central Florida College of Medicine, Orlando, Florida; University of Illinois College of Medicine, Urbana, Illinois; and Tufts Medical Center, Boston, Massachusetts, USA.W-H. Boehncke, MD; D. Alvarez Martinez, BS, Department of Dermatology, Geneva University Hospital; J.A. Solomon, MD, PhD, Ameriderm Research, University of Central Florida College of Medicine, University of Illinois College of Medicine; A.B. Gottlieb, MD, PhD, Tufts Medical Center.
authors.forename: Alice B
authors.initials: AB
authors.lastname: Gottlieb
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000627:therapeutic use; D015535:Arthritis, Psoriatic / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D001688:Biological Products / Q000627:therapeutic use; D017322:Clinical Trials, Phase II as Topic; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D061214:Patient Safety; D017410:Practice Guidelines as Topic / Q000592:standards*; D011379:Prognosis; D011565:Psoriasis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D016032:Randomized Controlled Trials as Topic; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D018501:Antirheumatic Agents; D001688:Biological Products
keywords: EFFICACY; PSORIASIS; PSORIASIS AREA AND SEVERITY INDEX; PSORIATIC ARTHRITIS; THERAPY