title: Predictors of coronary artery disease in patients with Behçet's disease.
abstract: BACKGROUND
  Behçet's disease (BD) is a multisystem vasculitis of unknown etiology. We aimed to determine the prevalence and predictors of coronary artery disease (CAD) in patients with BD.
  
  
  METHODS
  All adult patients diagnosed with BD from the National Inpatient Sample database using the International Classification of Diseases 9th revision (ICD-9 code 136.1) during 2009-2010 were included in the analysis. We analyzed the demographics, traditional risk factors, prevalence, and predictors of CAD in patients with BD using ICD-9 codes.
  
  
  RESULTS
  The prevalence of BD among adults was 0.006% (n = 2,540) of all in-hospital admissions in the USA. The mean age was 43.9 years, with women (45 years) being older than men (40 years) (p < 0.001). Traditional risk factors prevalent in our study were hypertension (35%), hyperlipidemia (17.4%), diabetes mellitus (13.8%), smoking (13.1%), and obesity (7.2%). The prevalence of CAD was 12.1%. Hypertension (OR = 2.20, p = 0.03) and hyperlipidemia (OR = 2.34, p = 0.02) were found to be independent predictors of CAD in a multimodel regression analysis.
  
  
  CONCLUSIONS
  In patients with BD, traditional risk factors associated with CAD were similar to what is expected in the overall population. However, the young age of patients with CAD in this population suggests an accelerated course of atherosclerosis in BD.
authors.affiliation: Division of Cardiology, Department of Medicine, University of Texas, Dallas, Tex., USA.
authors.forename: Ambarish
authors.initials: A
authors.lastname: Pandey
authors.forename: Jalaj
authors.initials: J
authors.lastname: Garg
authors.forename: Parasuram
authors.initials: P
authors.lastname: Krishnamoorthy
authors.forename: Chandrasekar
authors.initials: C
authors.lastname: Palaniswamy
authors.forename: Jay
authors.initials: J
authors.lastname: Doshi
authors.forename: Gregg
authors.initials: G
authors.lastname: Lanier
authors.forename: Hasan
authors.initials: H
authors.lastname: Ahmad
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000150:complications / Q000453:epidemiology*; D003324:Coronary Artery Disease / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D014481:United States / Q000453:epidemiology