title: A randomized clinical trial of nutrition education for improvement of diet quality and inflammation in Iranian obese women.
abstract: Background. Obesity is considered as a low grade inflammation condition. The aim of this study was to investigate the effect of nutritional education on diet quality and biomarkers of inflammation in Iranian obese women. Method. Sixty obese women voluntarily participated in this randomized clinical trial and were randomly assigned to intervention or control group (n = 30). Intervention group was instructed to attend nutrition education sessions (1 hr/wk, for 3 months) in small groups. Diet quality scores were measured by Healthy Eating Index (HEI). Anthropometric indices and serum concentration of hs-CRP, TNF-α, and adiponectin were measured at the baseline and end of the intervention. Results. There were no significant differences in anthropometric indices of participants between the two groups at the end of intervention (P > 0.05). However, the total HEI score was significantly higher in the educated group compared to the control group after intervention (P < 0.05). The educated group also showed significant lower concentration of TNF-α and hs-CRP and higher levels of adiponectin than the control group at the end of study (P < 0.05). Conclusions. Our results provide limited evidence that higher dietary quality contributes to reduced inflammation in obese women. This effect could be independent of the weight loss.
authors.affiliation: Hyperlipidemia Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz 61357-15794, Iran.
authors.forename: Majid
authors.initials: M
authors.lastname: Mohammadshahi
authors.affiliation: Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz 61357-15794, Iran.
authors.forename: Fatemeh
authors.identifier: 0000-0001-9104-4639
authors.initials: F
authors.lastname: Haidari
authors.affiliation: Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz 61357-15794, Iran.
authors.forename: Majid
authors.initials: M
authors.lastname: Karandish
authors.affiliation: Department of Nutritional Science, Arvand International Division of Ahvaz Jundishapur University of Medical Sciences, Ahvaz 61357-15794, Iran.
authors.forename: Sara
authors.initials: S
authors.lastname: Ebrahimi
authors.affiliation: School of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz 61357-15794, Iran.
authors.forename: Mohammad-Hosein
authors.initials: MH
authors.lastname: Haghighizadeh