title: The Clinical Trials Transformation Initiative: innovation through collaboration.
abstract: The Clinical Trials Transformation Initiative (CTTI) identifies and promotes practices to increase the quality and efficiency of clinical trials through projects that generate empirical data on how trials are currently conducted, leading to recommendations for improvement.
authors.affiliation: Clinical Trials Transformation Initiative, Duke Translational Medicine Institute, 300 West Morgan Street, Suite 800, Durham, North Carolina 27701, USA.
authors.forename: Pamela
authors.initials: P
authors.lastname: Tenaerts
authors.affiliation: Clinical Trials Transformation Initiative, Duke Translational Medicine Institute, 300 West Morgan Street, Suite 800, Durham, North Carolina 27701, USA.
authors.forename: Leanne
authors.initials: L
authors.lastname: Madre
authors.affiliation: Office of Medical Policy, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland 20993, USA.
authors.forename: Patrick
authors.initials: P
authors.lastname: Archdeacon
authors.affiliation: Duke Translational Medicine Institute, Durham, North Carolina 27710, USA.
authors.forename: Robert M
authors.initials: RM
authors.lastname: Califf
mesh_terms: D002986:Clinical Trials as Topic; D003299:Cooperative Behavior; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D014481:United States; D014486:United States Food and Drug Administration