title: A role for interleukin-22 in the alleviation of metabolic syndrome.
abstract: Increasing evidence points to a role for the immune system in the regulation of metabolism. Two new studies in mice indicate treatment with interleukin-22 restores mucosal immunity in diabetes and alleviates metabolic disease, resulting in improved glycemic control.
authors.affiliation: Clinic of Endocrinology, Diabetes and Metabolism, and the Department of Biomedicine, University of Basel, Basel, Switzerland.
authors.forename: Elise
authors.initials: E
authors.lastname: Dalmas
authors.affiliation: Clinic of Endocrinology, Diabetes and Metabolism, and the Department of Biomedicine, University of Basel, Basel, Switzerland.
authors.forename: Marc Y
authors.initials: MY
authors.lastname: Donath
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D016207:Cytokines / Q000276:immunology*; D003924:Diabetes Mellitus, Type 2 / Q000276:immunology*; D059865:Endoplasmic Reticulum Stress / Q000276:immunology*; D005786:Gene Expression Regulation / Q000276:immunology*; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D050417:Insulin-Secreting Cells / Q000276:immunology*
chemical_list: D001786:Blood Glucose; D016207:Cytokines; D007328:Insulin