title: Small molecules inhibit the RAS-like small GTPases RALA and RALB.
abstract: Small molecules that selectively bind RAL-GDP inhibit RAL activity and suppress tumor growth.
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D005347:Fibroblasts / Q000187:drug effects; D006801:Humans; D051379:Mice; D001749:Urinary Bladder Neoplasms / Q000378:metabolism; D020725:ral GTP-Binding Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism
chemical_list: D000970:Antineoplastic Agents; C483163:Ralb protein, human; C492198:RALA protein, human; D020725:ral GTP-Binding Proteins