title: Brachytherapy, a viable option of globe salvage in treatment of large ciliary body melanocytoma.
abstract: We report a case of large histopathologically proven melanocytoma of the ciliary body in a 15-year-old male, presented with rapid extraocular growth following incisional biopsy with scleral patch graft. We chose brachytherapy with Ruthenium 106 plaque over enucleation as the later was refused by the parents. The initial apical height of the tumor was 14.2 mm on ultrasonography. Two weeks after brachytherapy, the mass regressed to a size of 8.1 mm and 1 year later to 6.7 mm. This is the first case report showing the response of brachytherapy to ciliary body melanocytoma, which results in ocular and visual acuity salvation with considerable decreased in size of the tumor. The authors conclude that brachytherapy is an option in the management of non-resectable melanocytoma of the ciliary body.
authors.forename: Mahesh P
authors.initials: MP
authors.lastname: Shanmugam
authors.affiliation: Department of Vitreoretinal and Ocular Oncology Services, Sankara Eye Care Institutions, Bangalore, Karnataka, India.
authors.forename: Manish
authors.initials: M
authors.lastname: Saxena
authors.forename: Rajesh
authors.initials: R
authors.lastname: Ramanjulu
authors.forename: Pradeep
authors.initials: P
authors.lastname: Tekwani
mesh_terms: D000293:Adolescent; D044963:Biopsy, Fine-Needle; D001918:Brachytherapy / Q000379:methods*; D002924:Ciliary Body; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009508:Nevus, Pigmented / Q000473:pathology / Q000532:radiotherapy*; D016879:Salvage Therapy; D014604:Uveal Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D014792:Visual Acuity