title: Cross-reactivity syndromes: presentation of two cases and review of the literature.
abstract: Cross-reactivity has important consequences in some immune disorders, including allergic and autoimmune diseases, which can affect both diagnostic and therapeutic approaches. One of the most common cross-reactivity syndromes is pollen-food syndrome (PFS). The patient is sensitized with pollen by the airways and exhibits an allergic reaction to food antigen with a structural similarity to the pollen. PFS usually presents with pruritus and swelling of the mouth and throat during or just after ingestion of fresh, uncooked fruits and vegetables. Latex fruit syndrome is another cross-reactivity syndrome. It is the association of latex allergy and allergy to plant foods, which affects up to 50% of latex-allergic patients. Here, we present two cases with crossreactivity syndrome.
authors.affiliation: Division of Pediatric Allergy and Immunology, Department of Pediatrics, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey. drsakinekar83@hotmail.com.
authors.forename: Sakine
authors.initials: S
authors.lastname: Işık
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Arıkan-Ayyıldız
authors.forename: Şule
authors.initials: Ş
authors.lastname: Çağlayan-Sözmen
authors.forename: Fatih
authors.initials: F
authors.lastname: Fırıncı
authors.forename: Tuba
authors.initials: T
authors.lastname: Tuncel
authors.forename: Özkan
authors.initials: Ö
authors.lastname: Karaman
authors.forename: Nevin
authors.initials: N
authors.lastname: Uzuner
mesh_terms: D000293:Adolescent; D000485:Allergens / Q000009:adverse effects*; D052179:Antigens, Plant / Q000276:immunology*; D002648:Child; D003429:Cross Reactions; D005260:Female; D005512:Food Hypersensitivity / Q000209:etiology* / Q000276:immunology; D005638:Fruit / Q000009:adverse effects*; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D020315:Latex Hypersensitivity / Q000209:etiology* / Q000276:immunology; D008297:Male; D010940:Plant Proteins / Q000276:immunology*; D011058:Pollen / Q000009:adverse effects*; D012882:Skin Tests
chemical_list: D000485:Allergens; D052179:Antigens, Plant; D010940:Plant Proteins; D007073:Immunoglobulin E