title: [Juvenile polyposis syndrome is a rare cause of gastrointestinal cancer].
abstract: Juvenile polyposis syndrome is an autosomal dominant polyposis syndrome. It is characterized by predisposition to multiple juvenile polyps in the gastrointestinal tract and is associated with an increased risk of colorectal and ventricular cancer. Patients and at risk family members should be offered surveillance. This article discusses clinical features and surveillance based on the current literature.
authors.affiliation: Klinisk Genetisk Afdeling, Odense Universitetshospital, Sdr. Boulevard 29, 5000 Odense C. anne.marie.jelsig@rsyd.dk
authors.forename: Anne Marie
authors.initials: AM
authors.lastname: Jelsig
authors.forename: Pernille Mathiesen
authors.initials: PM
authors.lastname: Tørring
authors.forename: Niels
authors.initials: N
authors.lastname: Qvist
authors.forename: Inge
authors.initials: I
authors.lastname: Bernstein
authors.forename: Lilian Bomme
authors.initials: LB
authors.lastname: Ousager
mesh_terms: D052005:Bone Morphogenetic Protein Receptors, Type I / Q000235:genetics; D019091:Critical Pathways; D005770:Gastrointestinal Neoplasms / Q000209:etiology*; D018095:Germ-Line Mutation; D006801:Humans; D044483:Intestinal Polyposis / Q000150:complications / Q000151:congenital* / Q000175:diagnosis / Q000235:genetics / Q000473:pathology; D009386:Neoplastic Syndromes, Hereditary / Q000150:complications* / Q000175:diagnosis / Q000235:genetics / Q000473:pathology; D012307:Risk Factors; D051901:Smad4 Protein / Q000235:genetics; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000175:diagnosis / Q000235:genetics
chemical_list: D051901:Smad4 Protein; C498211:BMPR1A protein, human; D052005:Bone Morphogenetic Protein Receptors, Type I