title: Inertial focusing cytometer with integrated optics for particle characterization.
abstract: Microfluidic inertial focusing has been shown as a simple and effective method to localize cells and particles within a flow cell for interrogation by an external optical system. To enable portable point of care optical cytometry, however, requires a reduction in the complexity of the large optical systems that are used in standard flow cytometers. Here, we present a new design that incorporates optical waveguides and focusing elements with an inertial focusing flow cell to make a compact robust cytometer capable of enumerating and discriminating beads, cells, and platelets.
authors.affiliation: Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Shriners Hospitals for Children, Boston, MA 02114, USA.
authors.forename: Kenneth T
authors.initials: KT
authors.lastname: Kotz
authors.affiliation: Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Shriners Hospitals for Children, Boston, MA 02114, USA.
authors.forename: Anne C
authors.initials: AC
authors.lastname: Petrofsky
authors.affiliation: Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Shriners Hospitals for Children, Boston, MA 02114, USA.
authors.forename: Ramin
authors.initials: R
authors.lastname: Haghgooie
authors.affiliation: Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Shriners Hospitals for Children, Boston, MA 02114, USA.
authors.forename: Robert
authors.initials: R
authors.lastname: Granier
authors.affiliation: Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Shriners Hospitals for Children, Boston, MA 02114, USA.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Toner
authors.affiliation: Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Shriners Hospitals for Children, Boston, MA 02114, USA.
authors.forename: Ronald G
authors.initials: RG
authors.lastname: Tompkins