title: Serum lipoprotein(a) concentrations do not change significantly in the immediate seven-day period post myocardial infarction.
abstract: BACKGROUND
  Lipoprotein(a) is an independent predictor of cardiovascular disease and its variability after myocardial infarction was assessed in this study.
  
  
  METHODS
  Lipoprotein(a) was analysed by a size insensitive latex immunoturbidimetric end point assay in samples from days 0 to 7 in 31 patients admitted with myocardial infarction.
  
  
  RESULTS
  Median lipoprotein(a) changed by -0.9%, -0.1% and 9.6% on days 1, 2-3 and 4-7, respectively, and was not statistically significant. Median total cholesterol reduced by 8.7%, 9.1%, 14.5% and C-reactive protein increased by 68.4%, 510%, 502% over days 1, 2-3, 4-7, respectively.
  
  
  CONCLUSIONS
  Unlike total cholesterol and C-reactive protein, lipoprotein(a) does not demonstrate significant variability for up to seven days after myocardial infarction and measurements made during this period after myocardial infarction are physiologically meaningful.
authors.affiliation: Department of Chemical Pathology, University Hospitals of Leicester NHS Trust, Leicester, UK.
authors.forename: Prashanth
authors.initials: P
authors.lastname: Patel
authors.affiliation: Department of Chemical Pathology, University Hospitals of Leicester NHS Trust, Leicester, UK.
authors.forename: Timothy
authors.initials: T
authors.lastname: Davies
authors.affiliation: Department of Chemical Pathology, University Hospitals of Leicester NHS Trust, Leicester, UK.
authors.forename: Webster
authors.initials: W
authors.lastname: Madira
authors.affiliation: Department of Chemical Pathology, University Hospitals of Leicester NHS Trust, Leicester, UK pankaj.gupta@uhl-tr.nhs.uk.
authors.forename: Pankaj
authors.initials: P
authors.lastname: Gupta
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002097:C-Reactive Protein / Q000378:metabolism*; D002784:Cholesterol / Q000097:blood*; D003955:Diagnostic Tests, Routine / Q000592:standards* / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D017270:Lipoprotein(a) / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000175:diagnosis*; D011379:Prognosis; D013997:Time Factors
chemical_list: D017270:Lipoprotein(a); D002097:C-Reactive Protein; D002784:Cholesterol
keywords: Lipoprotein(a); acute-phase reactant; cardiovascular disease; cholesterol; myocardial infarction