title: Comparative study of aerobic pathogenic bacteria isolates from patients with recurrent tonsillitis.
abstract: BACKGROUND
  To find out if isolated aerobic bacteria pathogens from surface tonsillar swab can correctly predict the infective pathogens within the core tonsillar tissues in recurrent tonsillitis.
  
  
  METHODS
  This was a prospective, hospital based study of 60 patients with recurrent tonsillitis at University College Hospital, Ibadan, Nigeria. Surface swabs of the infected-tonsils-biopsies-of the core tonsillar tissues were obtained. Microscopy, Culture and Sensitivity studies were performed on the specimens. The aerobic pathogens were isolated by standard microbiological methods. Data analysis was done by SPSS version 20.0.
  
  
  RESULTS
  Only 54 (90%) surface swab specimens yielded aerobic pathogens while 47 (78.3%) core tissue specimens yielded aerobic pathogens. The tonsil surface swab for identification of aerobic pathogenic bacteria has a sensitivity of 97.7%, specificity of 31.3%, positive predictive value or precision of 79.6%, negative predictive value of 83.3% and accuracy of 80%. Overall, there was no statistical significant difference in the aerobic pathogenic organisms isolated from surface tonsillar swab and core tonsillar tissue specimens (p=0.103).
  
  
  CONCLUSIONS
  Aerobic bacteria pathogens grown on tonsillar surface were not significantly different from those from core tonsillar specimenshence, the tonsillar surface swab can reliably be used to identify the pathogenic organisms in recurrent tonsillitis.
authors.forename: D D
authors.initials: DD
authors.lastname: Douglas
authors.forename: A J
authors.initials: AJ
authors.lastname: Fasunla
authors.forename: S A
authors.initials: SA
authors.lastname: Fayemiwo
authors.forename: O G
authors.initials: OG
authors.lastname: Nwaorgu
mesh_terms: D000293:Adolescent; D001420:Bacteria, Aerobic / Q000302:isolation & purification*; D002648:Child; D002675:Child, Preschool; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis*; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis*; D006801:Humans; D008297:Male; D009549:Nigeria; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012008:Recurrence; D014069:Tonsillitis / Q000382:microbiology* / Q000473:pathology