title: Exceptionally strong hydrogels through self-assembly of an indole-capped dipeptide.
abstract: The synthesis of a new hydrogelator with an indole capping group, 1, is reported. 1 forms exceptionally strong hydrogels in a variety of environments, with values for the storage modulus G' amongst the highest reported for supramolecular hydrogels. These gels exhibit strong bundling characteristics, which gives the high values for G' observed. Cell viability studies show that at low concentrations, 1 is biocompatible, however upon self-assembly at higher concentrations, cytotoxic effects are observed.
authors.affiliation: School of Chemistry, The Australian Centre for Nanomedicine and the ARC Centre of Excellence for Convergent Bio-Nano Science and Technology, The University of New South Wales, Sydney, 2052, NSW, Australia. p.thordarson@unsw.edu.au.
authors.forename: Adam D
authors.initials: AD
authors.lastname: Martin
authors.forename: Andrew B
authors.initials: AB
authors.lastname: Robinson
authors.forename: Alexander F
authors.initials: AF
authors.lastname: Mason
authors.forename: Jonathan P
authors.initials: JP
authors.lastname: Wojciechowski
authors.forename: Pall
authors.initials: P
authors.lastname: Thordarson
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry* / Q000633:toxicity; D002470:Cell Survival / Q000187:drug effects; D004151:Dipeptides / Q000737:chemistry* / Q000633:toxicity; D006367:HeLa Cells; D006801:Humans; D020100:Hydrogels / Q000737:chemistry* / Q000633:toxicity; D007211:Indoles / Q000737:chemistry* / Q000633:toxicity
chemical_list: D001672:Biocompatible Materials; D004151:Dipeptides; D020100:Hydrogels; D007211:Indoles; C030374:indole