title: Effect of a weight loss program on body composition and metabolic syndrome markers in obese weight cyclers.
abstract: OBJECTIVE
  to evaluate the effect of weight loss program on fat mass, visceral fat rating and metabolic syndrome markers in obese subjects with weight cycling.
  
  
  METHODS
  this was an 8-week open trial. The subjects were recruited consecutively from Balai Kota DKI Jaya. Subjects were classified into two groups according to the fluctuation of weight gain (weight cycling/WC and first encounter obesity/FEO group). Both groups were assigned to receive weight loss program consisted with following goals: a 1000 kcal energy intake reduction and 45 minutes mild-to-moderate intensity physical activity three times a week. Body composition (fat mass, visceral fat rating), and metabolic syndrome markers (waist circumference and triglyceride levels) were measured at baseline, week 4 and at the end of study.
  
  
  RESULTS
  seventy two subjects completed the study (34 subjects in WC group and 38 subjects in FEO group). Following weight loss program, a decrease in fat mass, visceral fat rating, and waist circumference was lower in WC group compared with FEO group but it was not statistically significant (p>0.05). Triglyceride levels were decreased in the FEO group while it was increased in WC group. However the difference was not significant (p=0.055).
  
  
  CONCLUSIONS
  weight loss program may contribute to changes in body composition and metabolic syndrome markers in obese subjects, which the response appears to be worse in weight cyclers.
authors.affiliation: Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
authors.forename: Samuel
authors.initials: S
authors.lastname: Oetoro
authors.forename: Lukman H
authors.initials: LH
authors.lastname: Makmun
authors.forename: Widjaja
authors.initials: W
authors.lastname: Lukito
authors.forename: Andi
authors.initials: A
authors.lastname: Wijaya
mesh_terms: D050154:Adiposity; D000328:Adult; D015415:Biomarkers / Q000097:blood; D001823:Body Composition; D005260:Female; D006801:Humans; D050152:Intra-Abdominal Fat; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000150:complications / Q000473:pathology / Q000628:therapy*; D010865:Pilot Projects; D016896:Treatment Outcome; D014280:Triglycerides / Q000097:blood*; D055105:Waist Circumference; D061217:Weight Reduction Programs
chemical_list: D015415:Biomarkers; D014280:Triglycerides