title: Effect of repeated sprints on postprandial endothelial function and triacylglycerol concentrations in adolescent boys.
abstract: This study investigated whether repeated, very short duration sprints influenced endothelial function (indicated by flow-mediated dilation) and triacylglycerol concentrations following the ingestion of high-fat meals in adolescent boys. Nine adolescent boys completed two, 2-day main trials (control and exercise), in a counter-balanced, cross-over design. Participants were inactive on day 1 of the control trial but completed 40 × 6 s maximal cycle sprints on day 1 of the exercise trial. On day 2, capillary blood samples were collected and flow-mediated dilation measured prior to, and following, ingestion of a high-fat breakfast and lunch. Fasting flow-mediated dilation and plasma triacylglycerol concentration were similar in the control and exercise trial (P > 0.05). In the control trial, flow-mediated dilation was reduced by 20% and 27% following the high-fat breakfast and lunch; following exercise these reductions were negated (main effect trial, P < 0.05; interaction effect trial × time, P < 0.05). The total area under the plasma triacylglycerol concentration versus time curve was 13% lower on day 2 in the exercise trial compared to the control trial (8.65 (0.97) vs. 9.92 (1.16) mmol · l(-1) · 6.5 h, P < 0.05). These results demonstrate that repeated 6 s maximal cycle sprints can have beneficial effects on postprandial endothelial function and triacylglycerol concentrations in adolescent boys.
authors.affiliation: a School of Sport, Exercise and Health Sciences , Loughborough University , Loughborough , UK.
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Sedgwick
authors.forename: John G
authors.initials: JG
authors.lastname: Morris
authors.forename: Mary E
authors.initials: ME
authors.lastname: Nevill
authors.forename: Laura A
authors.initials: LA
authors.lastname: Barrett
mesh_terms: D061725:Accelerometry; D000293:Adolescent; D001642:Bicycling / Q000502:physiology*; D001786:Blood Glucose / Q000378:metabolism; D002648:Child; D018592:Cross-Over Studies; D004041:Dietary Fats / Q000008:administration & dosage*; D004730:Endothelium, Vascular / Q000502:physiology*; D006339:Heart Rate; D006801:Humans; D007328:Insulin / Q000097:blood; D008297:Male; D010465:Perception / Q000502:physiology; D005082:Physical Exertion / Q000502:physiology; D019518:Postprandial Period / Q000502:physiology*; D014280:Triglycerides / Q000097:blood*; D014664:Vasodilation
chemical_list: D001786:Blood Glucose; D004041:Dietary Fats; D007328:Insulin; D014280:Triglycerides
keywords: coronary heart disease risk; flow-mediated dilation; high-intensity exercise; postprandial lipaemia; repeated sprint exercise