title: Primary malignant non-Hodgkin's lymphoma of the breast: A case report.
abstract: Primary malignant lymphoma of the breast (PLB) is a rare disease. Treatment options include surgical resection, systemic chemotherapy, radiation and immunotherapy. At present, the optimum treatment combination remains controversial. The present study reports the case of a 39-year-old female with a six month history of a painless mass in the left breast. The mass was excised following medical examination. A diagnosis of diffuse large B-cell lymphoma was determined as a result of histological and immunohistochemical profile analysis. Further examinations excluded metastatic disease. Thus, finally, PLB (diffuse large B-cell lymphoma type) was diagnosed. The patient was treated with adjuvant systemic chemotherapy and consolidated radiation and a positive response was observed. During the 10 months of follow-up, no evidence of disease recurrence was identified. At present, the patient is scheduled for regular follow-up appointments. As the prevalence of PLB is increasing, the details of this rare case may aid clinicians treating similar patients, and highlight the importance of this disease.
authors.affiliation: Department of Pathology, Suining Central Hospital, Suining, Sichuan 629000, P.R. China.
authors.forename: Yun-Fei
authors.initials: YF
authors.lastname: Zhao
authors.affiliation: Department of Oncology, Shanghai Jiao Tong University Affiliated First People's Hospital, Shanghai 201620, P.R. China.
authors.forename: Feng
authors.initials: F
authors.lastname: Jiao
authors.affiliation: Department of Pathology, Suining Central Hospital, Suining, Sichuan 629000, P.R. China.
authors.forename: Hai-Qiao
authors.initials: HQ
authors.lastname: Liang
authors.affiliation: Department of Pathology, Suining Central Hospital, Suining, Sichuan 629000, P.R. China.
authors.forename: Qi-Chi
authors.initials: QC
authors.lastname: Luo
authors.affiliation: Department of Radiology, Suining Central Hospital, Suining, Sichuan 629000, P.R. China.
authors.forename: Lin-Wei
authors.initials: LW
authors.lastname: Zhao
keywords: breast lymphoma; immunohistochemistry; malignant lymphoma