title: Catalytic activity of a dual-hemin labelled oligonucleotide: conformational dependence and fluorescent DNA sensing.
abstract: The conformation-dependent peroxidase activity of a dual-hemin labelled oligonucleotide was identified and conveniently utilized to design a sensitive homogenous fluorescent method for DNA sensing.
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P.R. China. hxju@nju.edu.cn.
authors.forename: Quanbo
authors.initials: Q
authors.lastname: Wang
authors.forename: Nan
authors.initials: N
authors.lastname: Xu
authors.forename: Zhen
authors.initials: Z
authors.lastname: Gui
authors.forename: Jianping
authors.initials: J
authors.lastname: Lei
authors.forename: Huangxian
authors.initials: H
authors.lastname: Ju
authors.forename: Feng
authors.initials: F
authors.lastname: Yan
mesh_terms: D015374:Biosensing Techniques; D002384:Catalysis; D004247:DNA / Q000032:analysis* / Q000737:chemistry; D006427:Hemin / Q000737:chemistry*; D008968:Molecular Conformation; D009841:Oligonucleotides / Q000737:chemistry*; D009195:Peroxidase / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet; D014439:Tyramine / Q000737:chemistry
chemical_list: D009841:Oligonucleotides; D006427:Hemin; D004247:DNA; D009195:Peroxidase; D014439:Tyramine