title: Pulmonary infantile hemangioma presenting as a mass in a premature male infant: a case report focusing on pathological features.
abstract: Infantile hemangiomas are the most common benign neoplasm of infancy, with most occurring in the head and neck region. Predisposing factors include prematurity, low birth weight, multiple gestations, advanced maternal age, and chorionic villous sampling. In addition, white women, particularly those with a family history, are also at a higher risk. However, pulmonary infantile hemangiomas are exceedingly rare, with only a few case reports in the literature. Infantile hemangiomas should be considered in the differential diagnosis of a pulmonary mass in the early pediatric population. We present a case of pulmonary infantile hemangioma in a premature male infant successfully managed by surgical excision, with an emphasis on the pathogenesis and histologic features.
authors.affiliation: 1 Department of Pathology and Laboratory Medicine and Surgery, University of California Irvine Medical Center, 101 The City Drive, Orange, CA 92868, USA.
authors.forename: Parwiz J
authors.initials: PJ
authors.lastname: Siaghani
authors.forename: Claire
authors.initials: C
authors.lastname: Chavez
authors.forename: Dean M
authors.initials: DM
authors.lastname: Anselmo
authors.forename: Lisa
authors.initials: L
authors.lastname: Shane
mesh_terms: D003937:Diagnosis, Differential; D042783:Endothelial Cells / Q000166:cytology; D051272:Glucose Transporter Type 1 / Q000378:metabolism; D006391:Hemangioma / Q000175:diagnosis* / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008175:Lung Neoplasms / Q000175:diagnosis; D008297:Male; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D051272:Glucose Transporter Type 1; C495677:SLC2A1 protein, human
keywords: hemangioma; hemangioma of infancy; infantile hemangioma