title: Surgical interventions for treating pectus excavatum.
abstract: BACKGROUND
  Pectus excavatum is characterized by a depression of the anterior chest wall (sternum and lower costal cartilages) and is the most frequently occurring chest wall deformity. The prevalence ranges from 6.28 to 12 cases per 1000 around the world. Generally pectus excavatum is present at birth or is identified after a few weeks or months; however, sometimes it becomes evident only at puberty. The consequence of the condition on a individual's life is variable, some live a normal life and others have physical and psychological symptoms such as: precordial pain after exercises; impairments of pulmonary and cardiac function; shyness and social isolation. For many years, sub-perichondrial resection of the costal cartilages, with or without transverse cuneiform osteotomy of the sternum and placement of a substernal support, called conventional surgery, was the most accepted option for surgical repair of these patients. From 1997 a new surgical repair called, minimally invasive surgery, became available. This less invasive surgical option consists of the retrosternal placement of a curved metal bar, without resections of the costal cartilages or sternum osteotomy, and is performed by videothoracoscopy. However, many aspects that relate to the benefits and harms of both techniques have not been defined.
  
  
  OBJECTIVE
  To evaluate the effectiveness and safety of the conventional surgery compared with minimally invasive surgery for treating people with pectus excavatum.
  
  
  METHODS
  With the aim of increasing the sensitivity of the search strategy we used only terms related to the individual's condition (pectus excavatum); terms related to the interventions, outcomes and types of studies were not included. We searched the Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, Embase, LILACS, and ICTPR. Additionally we searched yet reference lists of articles and conference proceedings. All searches were done without language restriction.Date of the most recent searches: 14 January 2014.
  
  
  METHODS
  We considered randomized or quasi-randomized controlled trials that compared traditional surgery with minimally invasive surgery for treating pectus excavatum.
  
  
  METHODS
  Two review authors independently assessed the eligibility of the trials identified and agreed trial eligibility after a consensus meeting. The authors also assessed the risk of bias of the eligible trials.
  
  
  RESULTS
  Initially we located 4111 trials from the electronic searches and two further trials from other resources. All trials were added into reference management software and the duplicates were excluded, leaving 2517 studies. The titles and abstracts of these 2517 studies were independently analyzed by two authors and finally eight trials were selected for full text analysis, after which they were all excluded, as they did not fulfil the inclusion criteria.
  
  
  CONCLUSIONS
  There is no evidence from randomized controlled trials to conclude what is the best surgical option to treat people with pectus excavatum.
authors.affiliation: Evidence Based Health Actions Department and Thoracic Surgery Department, Marilia Medical School, Avenida Monte Carmelo, 800, Bairro Fragata, Marilia, Sao Paulo, Brazil, 17519-030.
authors.forename: Paulo Eduardo
authors.initials: PE
authors.lastname: de Oliveira Carvalho
authors.forename: Marcos Vinícius Muriano
authors.initials: MV
authors.lastname: da Silva
authors.forename: Olavo Ribeiro
authors.initials: OR
authors.lastname: Rodrigues
authors.forename: Antonio José Maria
authors.initials: AJ
authors.lastname: Cataneo
mesh_terms: D005660:Funnel Chest / Q000601:surgery*; D006801:Humans; D010027:Osteotomy / Q000009:adverse effects / Q000379:methods*; D016032:Randomized Controlled Trials as Topic; D020775:Thoracic Surgery, Video-Assisted / Q000009:adverse effects