title: Written production in a case of locked-in syndrome with bilateral corticopontic degeneration.
abstract: Patients in locked-in syndrome show normal or near normal mental abilities that contrast with the limited motor capacity that hinders voluntary communication. However, eye movements and blinking are usually preserved and can be used to establish a communication system. We report an exceptional case of locked-in syndrome. The aetiology was basilar thrombosis consecutive to a cervical manipulation. In addition, brain MRI performed 23 years later showed a ventral pontine stroke with bilateral corticopontic degeneration. In this study the patient was able to produce written output using a chin-controlled Morse system decoded by a computer. A detailed linguistic analysis of text written over 20 years by the patient was carried out. The data demonstrate that improvements in language performance can be observed even in patients with brain lesions in areas associated with high-level cognitive processes. The data show a decrease of typing, grammatical and lexical errors over time, use of less frequent words, and an increase of more complex linguistic structures. This paper adds to previous findings confirming the value of daily practice and rehabilitation to enhance quality of life in this group of patients.
authors.affiliation: a Université de Lyon, Université Lumière , Lyon , France.
authors.forename: F
authors.initials: F
authors.lastname: Gayraud
authors.forename: B
authors.initials: B
authors.lastname: Martinie
authors.forename: E
authors.initials: E
authors.lastname: Bentot
authors.forename: A
authors.initials: A
authors.lastname: Lepilliez
authors.forename: L
authors.initials: L
authors.lastname: Tell
authors.forename: F
authors.initials: F
authors.lastname: Cotton
authors.forename: G
authors.initials: G
authors.lastname: Rode
mesh_terms: D001921:Brain / Q000473:pathology; D003143:Communication Devices for People with Disabilities; D005260:Female; D006801:Humans; D008037:Linguistics; D008875:Middle Aged; D011782:Quadriplegia / Q000473:pathology / Q000523:psychology* / Q000534:rehabilitation*; D014956:Writing
keywords: Communication; Language; Locked-in syndrome; Rehabilitation; Written production