title: Evaluation of Occlusion Treatment Outcomes for Unilateral Amblyopia Using Different Definitions of Outcome.
abstract: We studied 87 cases of children aged 3 to 10 with unilateral amblyopia (with types of anisometropia, strabismus, or both) who received good recovery after occlusion therapy. The proportional improvement had moderate positive correlation with amblyopic eye improvement (p < 0.05) and negative correlation with residual amblyopia (p < 0.05); the amblyopia residual had no correlation with amblyopic eye improvement (p < 0.05). In multivariate analysis, the proportion of the deficit-corrected of the <5 years group with 2 h/d occlusion therapy group displayed the best outcome (p < 0.05). The BCVA of amblyopia eye and residual amblyopia are simple and direct indicators for clinical application. The proportion of the deficit-corrected method should be graded as the proportion of change in visual acuity with respect to the absolute potential for improvement, and these optimum outcomes can provide powerful evidence for good therapeutic effect.
authors.affiliation: a Department of Ophthalmology , Tangdu Hospital, Fourth Military Medical University , Xi'an , China , and.
authors.forename: Liping
authors.initials: L
authors.lastname: Su
authors.affiliation: a Department of Ophthalmology , Tangdu Hospital, Fourth Military Medical University , Xi'an , China , and.
authors.forename: Hong
authors.initials: H
authors.lastname: Yan
authors.affiliation: a Department of Ophthalmology , Tangdu Hospital, Fourth Military Medical University , Xi'an , China , and.
authors.forename: Yongxin
authors.initials: Y
authors.lastname: Xing
authors.affiliation: b Department of Health Statistics , Fourth Military Medical University , Xi'an , China.
authors.forename: Yuhai
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: a Department of Ophthalmology , Tangdu Hospital, Fourth Military Medical University , Xi'an , China , and.
authors.forename: Baoyi
authors.initials: B
authors.lastname: Zhu
mesh_terms: D000550:Amblyopia / Q000145:classification / Q000503:physiopathology / Q000628:therapy*; D015858:Anisometropia / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D012029:Refraction, Ocular / Q000502:physiology; D042262:Retinoscopy; D012683:Sensory Deprivation; D013285:Strabismus / Q000628:therapy; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology
keywords: Amblyopic eye improvement; occlusion therapy; residual amblyopia; treatment of amblyopia; visual acuity