title: Continued seasonal circulation of enterovirus D68 in the Netherlands, 2011-2014.
abstract: Enterovirus D68 (EV-D68) continued to circulate in a seasonal pattern in the Netherlands, after the outbreak in 2010. Outpatient EV-D68 cases, mainly in the under 20 and 50–59 years age groups, presented with relatively mild respiratory disease. Hospital-based enterovirus surveillance identified more severe cases, mainly in children under 10 years of age. Dutch partial VP1 genomic region sequences from 2012 through 2014 were distributed over three sublineages similar to EV-D68 from the outbreak in the US in 2014.
authors.affiliation: Centre for Infectious Disease Research, Diagnostics and Screening, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
authors.forename: A
authors.initials: A
authors.lastname: Meijer
authors.forename: K S
authors.initials: KS
authors.lastname: Benschop
authors.forename: G A
authors.initials: GA
authors.lastname: Donker
authors.forename: H G
authors.initials: HG
authors.lastname: van der Avoort
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D030016:Enterovirus D, Human / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D004769:Enterovirus Infections / Q000453:epidemiology / Q000821:virology*; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009426:Netherlands / Q000453:epidemiology; D010802:Phylogeny; D012141:Respiratory Tract Infections / Q000453:epidemiology / Q000821:virology; D012189:Retrospective Studies; D012621:Seasons; D018571:Sentinel Surveillance; D017422:Sequence Analysis, DNA; D017678:Sex Distribution; D055815:Young Adult