title: [Cancer unmasked or provoked by immunosuppressive therapy].
abstract: The association between immunosuppressive therapy and cancer is to discussion. The overall risk is, however, still to be fully investigated. We describe two patients who had skin manifestations treated with immunosuppressive therapy and shortly afterwards were diagnosed with cancer. The skin diseases in question, vasculitis and pyoderma gangraenosum, can themselves be associated with cancer. However, treating these diseases with immunosuppressive therapy may potentially unmask or provoke an underlying cancer.
authors.affiliation: Dermatologisk Afdeling, Aarhus Universitetshospital, P.P. Ørumsgade 11, 8000 Aarhus C. bertelsen.trine@gmail.com
authors.forename: Trine
authors.initials: T
authors.lastname: Bertelsen
authors.forename: Karsten
authors.initials: K
authors.lastname: Fogh
mesh_terms: D000368:Aged; D016572:Cyclosporine / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D000069285:Infliximab / Q000009:adverse effects* / Q000627:therapeutic use; D008175:Lung Neoplasms / Q000139:chemically induced*; D016393:Lymphoma, B-Cell / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D017511:Pyoderma Gangrenosum / Q000150:complications / Q000188:drug therapy; D014657:Vasculitis / Q000150:complications / Q000188:drug therapy
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine; D000069285:Infliximab