title: Development of a security system for assisted reproductive technology (ART).
abstract: OBJECTIVE
  In the field of assisted reproductive technology (ART), medical accidents can result in serious legal and social consequences. This study was conducted to develop a security system (called IVF-guardian; IG) that could prevent mismatching or mix-ups in ART.
  
  
  METHODS
  A software program was developed in collaboration with outside computer programmers. A quick response (QR) code was used to identify the patients, gametes and embryos in a format that was printed on a label. There was a possibility that embryo development could be affected by volatile organic components (VOC) in the printing material and adhesive material in the label paper. Further, LED light was used as the light source to recognize the QR code. Using mouse embryos, the effects of the label paper and LED light were examined. The stability of IG was assessed when applied in clinical practice after developing the system. A total of 104 cycles formed the study group, and 82 cycles (from patients who did not want to use IG because of safety concerns and lack of confidence in the security system) to which IG was not applied comprised the control group.
  
  
  RESULTS
  Many of the label paper samples were toxic to mouse embryo development. We selected a particular label paper (P touch label) that did not affect mouse embryo development. The LED lights were non-toxic to the development of the mouse embryos under any experimental conditions. There were no differences in the clinical pregnancy rates between the IG-applied group and the control group (40/104 = 38.5 % and 30/82 = 36.6 %, respectively).
  
  
  CONCLUSIONS
  The application of IG in clinical practice did not affect human embryo development or clinical outcomes. The use of IG reduces the misspelling of patient names. Using IG, there was a disadvantage in that each treatment step became more complicated, but the medical staff improved and became sufficiently confident in ART to offset this disadvantage. Patients who received treatment using the IG system also went through a somewhat tedious process, but there were no complaints. These patients gained further confidence in the practitioners over the course of treatment.
authors.affiliation: Maria Fertility Hospital, 20 Cheonho-daero Dongdaemun-gu, Seoul, South Korea, 130-812, geaher@mariababy.com.
authors.forename: Yong Soo
authors.initials: YS
authors.lastname: Hur
authors.forename: Eun Kyung
authors.initials: EK
authors.lastname: Ryu
authors.forename: Sung Jin
authors.initials: SJ
authors.lastname: Park
authors.forename: Jeong
authors.initials: J
authors.lastname: Yoon
authors.forename: San Hyun
authors.initials: SH
authors.lastname: Yoon
authors.forename: Gi Deok
authors.initials: GD
authors.lastname: Yang
authors.forename: Chang Young
authors.initials: CY
authors.lastname: Hur
authors.forename: Won Don
authors.initials: WD
authors.lastname: Lee
authors.forename: Jin Ho
authors.initials: JH
authors.lastname: Lim
mesh_terms: D000818:Animals; D005260:Female; D005854:Germ Cells / Q000502:physiology; D006801:Humans; D051379:Mice; D011247:Pregnancy; D018873:Pregnancy Rate; D027724:Reproductive Techniques, Assisted; D012449:Safety; D012984:Software