title: Prevalence of osteoporosis in female patients with advanced knee osteoarthritis undergoing total knee arthroplasty.
abstract: This study sought to demonstrate bone mineral density (BMD) conditions in elderly female patients with knee osteoarthritis (OA) undergoing total knee arthroplasty (TKA). In addition, we sought to determine whether their BMD conditions differ from those of community-based females without knee OA. Finally we sought to determine whether clinical statuses are related to BMD in the knee OA patients. BMD conditions in 347 female patients undergoing TKA and 273 community-based females were evaluated. Additionally, comparative analyses of BMD between age and body mass index-matched knee OA groups (n=212) and the control groups (n=212) were performed. In the pre-matched knee OA group, regression analyses were performed to determine whether preoperative clinical statuses were related to BMD. Considerable prevalence of coexistent osteoporosis (31%) was found in the pre-matched knee OA patients undergoing TKA. We found no significant differences of the BMD T-scores and the prevalence of osteoporosis between the age and body mass index-matched knee OA and control groups. In the pre-matched knee OA patients, poorer preoperative clinical scores were related to poorer BMD T-scores in the proximal femur and/or lumbar spine. Our study suggests that more attention should be paid to identify and treat osteoporosis in elderly female patients with advanced knee OA undergoing TKA.
authors.affiliation: Department of Orthopedic Surgery, Seoul National University College of Medicine, Seoul, Korea. ; Department of Orthopedic Surgery SMG-SNU Boramae Medical Center, Seoul, Korea.
authors.forename: Chong Bum
authors.identifier: 0000-0002-8597-1054
authors.initials: CB
authors.lastname: Chang
authors.affiliation: Department of Orthopedic Surgery, Seoul National University College of Medicine, Seoul, Korea. ; Department of Orthopedic Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Tae Kyun
authors.identifier: 0000-0001-6345-4227
authors.initials: TK
authors.lastname: Kim
authors.affiliation: Department of Orthopedic Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Yeon Gwi
authors.identifier: 0000-0002-3346-0068
authors.initials: YG
authors.lastname: Kang
authors.affiliation: Department of Orthopedic Surgery, Seoul National University College of Medicine, Seoul, Korea. ; Department of Orthopedic Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Sang Cheol
authors.identifier: 0000-0003-0613-538X
authors.initials: SC
authors.lastname: Seong
authors.affiliation: Department of Orthopedic Surgery, Seoul National University College of Medicine, Seoul, Korea. ; Department of Orthopedic Surgery SMG-SNU Boramae Medical Center, Seoul, Korea.
authors.forename: Seung-Baik
authors.identifier: 0000-0002-1184-4482
authors.initials: SB
authors.lastname: Kang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee; D015992:Body Mass Index; D015519:Bone Density; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000473:pathology / Q000601:surgery; D020370:Osteoarthritis, Knee / Q000453:epidemiology* / Q000601:surgery*; D010024:Osteoporosis / Q000453:epidemiology*
keywords: Arthroplasty; Bone Density; Female Knee Osteoarthritis Patient; Knee; Osteoporosis