title: The immunosuppressive activity of MDSCs requires expression of CHOP.
abstract: The stress sensor CHOP enhances the accumulation and inhibitory activity of MDSCs in tumors.
mesh_terms: D000818:Animals; D006801:Humans; D007108:Immune Tolerance; D051379:Mice; D022423:Myeloid Cells / Q000276:immunology* / Q000378:metabolism; D009369:Neoplasms / Q000276:immunology / Q000378:metabolism; D013601:T-Lymphocytes / Q000276:immunology; D051742:Transcription Factor CHOP / Q000235:genetics / Q000276:immunology* / Q000378:metabolism
chemical_list: C497249:DDIT3 protein, human; D051742:Transcription Factor CHOP