title: Circulating fetuin-A in patients with pancreatic cancer: a hospital-based case-control study.
abstract: BACKGROUND
  A proteomic analysis has proposed fetuin-A (alpha-2-HS-glycoprotein) as a new potential marker for pancreatic cancer (PC).
  
  
  OBJECTIVE
  Circulating fetuin-A levels in patients with PC.
  
  
  METHODS
  Serum fetuin-A was measured in 81 cases with PC and 81 matched controls before the initiation of any treatment.
  
  
  RESULTS
  Serum fetuin-A was not independently associated with the presence of PC. Although there was a trend with higher fetuin-A levels across PC stages, comparisons of fetuin-A in patients within different PC prognostic stages revealed no differences.
  
  
  CONCLUSIONS
  Circulating fetuin-A was similar between patients and controls and was not associated with the disease severity.
authors.affiliation: Department of Clinical Biochemistry, Medical School, University of Athens, "Attikon" General University Hospital , Athens , Greece .
authors.forename: Maria
authors.initials: M
authors.lastname: Dalamaga
authors.forename: Stergios A
authors.initials: SA
authors.lastname: Polyzos
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Karmaniolas
authors.forename: John
authors.initials: J
authors.lastname: Chamberland
authors.forename: Antigoni
authors.initials: A
authors.lastname: Lekka
authors.forename: Ilias
authors.initials: I
authors.lastname: Migdalis
authors.forename: Evangelia
authors.initials: E
authors.lastname: Papadavid
authors.forename: Amalia
authors.initials: A
authors.lastname: Dionyssiou-Asteriou
authors.forename: Christos S
authors.initials: CS
authors.lastname: Mantzoros
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood*; D016022:Case-Control Studies; D005260:Female; D006761:Hospitals; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000097:blood*; D060749:alpha-2-HS-Glycoprotein / Q000378:metabolism*
chemical_list: D014408:Biomarkers, Tumor; D060749:alpha-2-HS-Glycoprotein
keywords: Alpha-2-HS-glycoprotein; insulin; insulin resistance; leptin; malignancy; pancreas