title: Breast cancer resistance protein substrate and inhibition evaluation: why, when, and how?
authors.affiliation: Clinical Pharmacology, Genentech, South San Francisco, California (J.A.W.); University of Western Ontario, London, Ontario, Canada (B.L.U.); RIKEN Innovation Center, Yokohama, Kanagawa, Japan (Y.S.); and Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Research Triangle Park, North Carolina (M.J.Z.-G.) ware.joseph@gene.com.
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Ware
authors.affiliation: Clinical Pharmacology, Genentech, South San Francisco, California (J.A.W.); University of Western Ontario, London, Ontario, Canada (B.L.U.); RIKEN Innovation Center, Yokohama, Kanagawa, Japan (Y.S.); and Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Research Triangle Park, North Carolina (M.J.Z.-G.).
authors.forename: Bradley L
authors.initials: BL
authors.lastname: Urquhart
authors.affiliation: Clinical Pharmacology, Genentech, South San Francisco, California (J.A.W.); University of Western Ontario, London, Ontario, Canada (B.L.U.); RIKEN Innovation Center, Yokohama, Kanagawa, Japan (Y.S.); and Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Research Triangle Park, North Carolina (M.J.Z.-G.).
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Sugiyama
authors.affiliation: Clinical Pharmacology, Genentech, South San Francisco, California (J.A.W.); University of Western Ontario, London, Ontario, Canada (B.L.U.); RIKEN Innovation Center, Yokohama, Kanagawa, Japan (Y.S.); and Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Research Triangle Park, North Carolina (M.J.Z.-G.).
authors.forename: Maciej J
authors.initials: MJ
authors.lastname: Zamek-Gliszczynski
mesh_terms: D018528:ATP-Binding Cassette Transporters / Q000037:antagonists & inhibitors*; D000818:Animals; D006801:Humans; D009363:Neoplasm Proteins / Q000037:antagonists & inhibitors*; D004364:Pharmaceutical Preparations / Q000378:metabolism*
chemical_list: D018528:ATP-Binding Cassette Transporters; D009363:Neoplasm Proteins; D004364:Pharmaceutical Preparations