title: Efficacy and safety of semicircular canal occlusion for intractable horizontal semicircular benign paroxysmal positional vertigo.
abstract: BACKGROUND
  Some studies have suggested that semicircular canal occlusion is effective and safe for treating intractable posterior semicircular benign paroxysmal positional vertigo (PSC-BPPV), and adverse effects of canal occlusions for intractable horizontal semicircular BPPV (HSC-BPPV) were rarely reported. The aim of this study was to retrospectively discuss the efficacy of semicircular canal occlusion for intractable HSC-BPPV with at least 2 years of follow-up.
  
  
  METHODS
  From 2000 to 2011, 3 female patients (average age=60±6.9 years), with a diagnosis of HSC-BPPV refractory to head-shake and barbecue roll maneuver, underwent semicircular canal occlusion treatment in our hospital. The supine roll test was performed to diagnose HSC-BPPV and evaluate the treatment efficacy.
  
  
  RESULTS
  All patients with intractable HSC-BPPV had complete resolution of their positional vertigo after semicircular canal occlusion with a negative supine roll test. All patients reported transient postoperative disequilibrium, nausea, and vomiting, which resolved within 2 weeks. In addition, 1 patient (33.3%) had transient tinnitus, which resolved after 4 months. There were no other significant long-term complications.
  
  
  CONCLUSIONS
  Semicircular canal occlusion appears to be a safe and well-tolerated treatment modality for intractable HSC-BPPV. However, further studies with large sample sizes are needed to confirm our conclusion.
authors.affiliation: Department of Ear, Nose and Throat, Changzheng Hospital, Shanghai, China.
authors.forename: Qiubei
authors.initials: Q
authors.lastname: Zhu
authors.affiliation: Department of Ear, Nose and Throat, Longhua Hospital, Shanghai, China.
authors.forename: Chang
authors.initials: C
authors.lastname: Liu
authors.affiliation: Department of Ear, Nose and Throat, The PLA 452nd Hospital, Chengdu, Sichuan Province, China.
authors.forename: Cheng
authors.initials: C
authors.lastname: Lin
authors.affiliation: Department of Neurology, Chengdu, The PLA 452nd Hospital, Sichuan Province, China.
authors.forename: Xian
authors.initials: X
authors.lastname: Chen
authors.affiliation: Department of Ear, Nose and Throat, The PLA 452nd Hospital, Chengdu, Sichuan Province, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Liu
authors.affiliation: Department of Ear, Nose and Throat, Changzheng Hospital, Shanghai, China linshunzhang@hotmail.com.
authors.forename: Shunzhang
authors.initials: S
authors.lastname: Lin
authors.affiliation: Department of Ear, Nose and Throat, Changzheng Hospital, Shanghai, China.
authors.forename: Jingping
authors.initials: J
authors.lastname: Fan
mesh_terms: D000368:Aged; D065635:Benign Paroxysmal Positional Vertigo / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D013506:Otologic Surgical Procedures / Q000379:methods*; D011187:Posture / Q000502:physiology*; D012189:Retrospective Studies; D012665:Semicircular Canals / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome
keywords: benign paroxysmal positional vertigo; canalolithiasis; cupulolithiasis; nystagmus; semicircular canal occlusion; supine roll test