title: Gene: a gene-centered information resource at NCBI.
abstract: The National Center for Biotechnology Information's (NCBI) Gene database (www.ncbi.nlm.nih.gov/gene) integrates gene-specific information from multiple data sources. NCBI Reference Sequence (RefSeq) genomes for viruses, prokaryotes and eukaryotes are the primary foundation for Gene records in that they form the critical association between sequence and a tracked gene upon which additional functional and descriptive content is anchored. Additional content is integrated based on the genomic location and RefSeq transcript and protein sequence data. The content of a Gene record represents the integration of curation and automated processing from RefSeq, collaborating model organism databases, consortia such as Gene Ontology, and other databases within NCBI. Records in Gene are assigned unique, tracked integers as identifiers. The content (citations, nomenclature, genomic location, gene products and their attributes, phenotypes, sequences, interactions, variation details, maps, expression, homologs, protein domains and external databases) is available via interactive browsing through NCBI's Entrez system, via NCBI's Entrez programming utilities (E-Utilities and Entrez Direct) and for bulk transfer by FTP.
authors.affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20892-6510, USA.
authors.forename: Garth R
authors.initials: GR
authors.lastname: Brown
authors.affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20892-6510, USA.
authors.forename: Vichet
authors.initials: V
authors.lastname: Hem
authors.affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20892-6510, USA.
authors.forename: Kenneth S
authors.initials: KS
authors.lastname: Katz
authors.affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20892-6510, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Ovetsky
authors.affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20892-6510, USA.
authors.forename: Craig
authors.initials: C
authors.lastname: Wallin
authors.affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20892-6510, USA.
authors.forename: Olga
authors.initials: O
authors.lastname: Ermolaeva
authors.affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20892-6510, USA.
authors.forename: Igor
authors.initials: I
authors.lastname: Tolstoy
authors.affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20892-6510, USA.
authors.forename: Tatiana
authors.initials: T
authors.lastname: Tatusova
authors.affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20892-6510, USA.
authors.forename: Kim D
authors.initials: KD
authors.lastname: Pruitt
authors.affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20892-6510, USA.
authors.forename: Donna R
authors.initials: DR
authors.lastname: Maglott
authors.affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20892-6510, USA murphyte@ncbi.nlm.nih.gov.
authors.forename: Terence D
authors.initials: TD
authors.lastname: Murphy
mesh_terms: D030541:Databases, Genetic; D005796:Genes; D014644:Genetic Variation; D023281:Genomics; D020407:Internet; D009317:National Library of Medicine (U.S.); D010641:Phenotype; D014481:United States