title: Chorion genes: a landscape of their evolution, structure, and regulation.
abstract: Differential regulation at the level of transcription provides a means for controlling gene expression in eukaryotes, especially during development. Insect model systems have been extensively used to decipher the molecular basis of such regulatory cascades, and one of the oldest such model systems is the regulation of chorion gene expression during ovarian follicle maturation. Recent experimental and technological advances have shed new light onto the system, allowing us to revisit it. Thus, in this review we try to summarize almost 40 years' worth of studies on chorion gene regulation while-by comparing Bombyx mori and Drosophila melanogaster models-attempting to present a comprehensive, unified model of the various regulatory aspects of choriogenesis that takes into account the evolutionary conservation and divergence of the underlying mechanisms.
authors.affiliation: Research Group for Systems Biology of Chromatin, Center for Molecular Medicine, University of Cologne, 50931 Cologne, Germany; email: argyris.papantonis@uni-koeln.de.
authors.forename: Argyris
authors.initials: A
authors.lastname: Papantonis
authors.forename: Luc
authors.initials: L
authors.lastname: Swevers
authors.forename: Kostas
authors.initials: K
authors.lastname: Iatrou
mesh_terms: D000818:Animals; D005075:Biological Evolution; D012831:Bombyx / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D002823:Chorion / Q000254:growth & development / Q000378:metabolism; D004331:Drosophila melanogaster / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D004527:Egg Proteins / Q000235:genetics* / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental; D019476:Insect Proteins / Q000235:genetics* / Q000378:metabolism; D011679:Pupa / Q000254:growth & development / Q000378:metabolism
chemical_list: D004527:Egg Proteins; D019476:Insect Proteins; C015753:chorion proteins
keywords: bidirectional promoters; choriogenesis; cis-element architecture; differential gene expression; transcription factors; vitellogenesis