title: Moyamoya syndrome associated with hemoglobin Southampton (Casper).
abstract: When moyamoya vasculopathy results from an associated disease, this vasculopathy is then referred to as moyamoya syndrome. Moyamoya syndrome has been reported in association with sickle cell disease, neurofibromatosis type 1, Down syndrome, radiation exposure, and other predisposing factors. Other than sickle cell disease, rare hemoglobinopathies, such as hemoglobin Fairfax and hemoglobin Alesha, have been reported to occur with moyamoya. We present a case of moyamoya syndrome associated with an unstable hemoglobinopathy, hemoglobin Southampton (Casper). This is the first reported case of moyamoya associated with this hemoglobinopathy.
authors.affiliation: Department of Neurosurgery, University of Michigan, Ann Arbor, Mich., USA.
authors.forename: Nader
authors.initials: N
authors.lastname: Delavari
authors.forename: Jennifer
authors.initials: J
authors.lastname: Strahle
authors.forename: Cormac O
authors.initials: CO
authors.lastname: Maher
mesh_terms: D002675:Child, Preschool; D005260:Female; D006455:Hemoglobins, Abnormal / Q000032:analysis; D006801:Humans; D009072:Moyamoya Disease / Q000097:blood / Q000000981:diagnostic imaging* / Q000601:surgery*; D011859:Radiography
chemical_list: D006455:Hemoglobins, Abnormal; C058164:hemoglobin Southampton