title: Pseudouridine in a new era of RNA modifications.
abstract: Two articles recently published in Nature and Cell report the first transcriptome-wide maps of pseudouridine (Ψ) at single-base resolution through selective chemical labeling, suggesting new mechanisms and functions of Ψ in mRNA and non-coding RNA molecules.
authors.affiliation: Department of Chemistry and Institute for Biophysical Dynamics, Howard Hughes Medical Institute, 929 East 57th Street, The University of Chicago, Chicago, IL, 60637, USA.
authors.forename: Boxuan Simen
authors.initials: BS
authors.lastname: Zhao
authors.affiliation: Department of Chemistry and Institute for Biophysical Dynamics, Howard Hughes Medical Institute, 929 East 57th Street, The University of Chicago, Chicago, IL, 60637, USA.
authors.forename: Chuan
authors.initials: C
authors.lastname: He
mesh_terms: D000818:Animals; D006801:Humans; D011560:Pseudouridine / Q000032:analysis*; D012333:RNA, Messenger / Q000737:chemistry*; D022661:RNA, Untranslated / Q000737:chemistry*; D012441:Saccharomyces cerevisiae / Q000235:genetics*
chemical_list: D012333:RNA, Messenger; D022661:RNA, Untranslated; D011560:Pseudouridine