title: Successful treatment of hepatocellular carcinoma with lung metastasis using hepatic and bronchial artery infusion chemotherapy.
abstract: We herein report a case of hepatocellular carcinoma (HCC) with lung metastasis that was successfully treated with transcatheter arterial infusion chemotherapy via the hepatic and bronchial arteries. A 64-year-old man diagnosed with HCC in 2003 was treated with locoregional therapy followed by sorafenib for recurrent HCC. Tumor thrombosis and lung metastasis were noted in April 2012. We administered IA-call(®), a fine-powder formulation of cisplatin, via the hepatic and bronchial arteries. This therapy resulted in the disappearance of the lung metastases and a partial response to tumor thrombosis. The patient remained alive for 23 months after developing lung metastasis.
authors.affiliation: Department of Gastroenterology and Neurology, Akita University Graduate School of Medicine, Japan.
authors.forename: Tatsuki
authors.initials: T
authors.lastname: Yoshida
authors.forename: Kentaro
authors.initials: K
authors.lastname: Kamada
authors.forename: Kouichi
authors.initials: K
authors.lastname: Miura
authors.forename: Takashi
authors.initials: T
authors.lastname: Goto
authors.forename: Shigetoshi
authors.initials: S
authors.lastname: Ohshima
authors.forename: Wataru
authors.initials: W
authors.lastname: Sato
authors.forename: Tomomi
authors.initials: T
authors.lastname: Shibuya
authors.forename: Takahiro
authors.initials: T
authors.lastname: Dohmen
authors.forename: Ryo
authors.initials: R
authors.lastname: Kanata
authors.forename: Toshitaka
authors.initials: T
authors.lastname: Sakai
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Chiba
authors.forename: Junichi
authors.initials: J
authors.lastname: Fujiwara
authors.forename: Yuko
authors.initials: Y
authors.lastname: Sugimoto
authors.forename: Mitsuaki
authors.initials: M
authors.lastname: Ishioka
authors.forename: Itsuki
authors.initials: I
authors.lastname: Hasegawa
authors.forename: Kenichi
authors.initials: K
authors.lastname: Takahashi
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Minami
authors.forename: Akashi
authors.initials: A
authors.lastname: Fujita
authors.forename: Manabu
authors.initials: M
authors.lastname: Hashimoto
authors.forename: Hirohide
authors.initials: H
authors.lastname: Ohnishi
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001981:Bronchial Arteries; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy* / Q000556:secondary*; D002945:Cisplatin / Q000008:administration & dosage*; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000379:methods; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000473:pathology; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D008875:Middle Aged
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin