title: Ectodermal dysplasia associated with sickle cell disease.
abstract: Ectodermal dysplasia and sickle cell anaemia are inherited disorders that affect, respectively, the tissues derived from the embryonic ectoderm and the production of erythrocytes by the bone marrow. The simultaneous occurrence of both disorders is extremely rare. This is a case of both ectodermal dysplasia and sickle cell anaemia reported in a 6-year-old. The patient had been diagnosed with sickle cell anaemia for only six months when he sought treatment presenting with the following: hypotrichosis, dry skin, periocular hyperpigmentation, protruding lips, hypodontia, and morphologically altered teeth. The clinical features combined with his medical history led to the diagnosis of ectodermal dysplasia. Dentists should be prepared to recognise patterns that escape normality to aid in the diagnosis of systemic changes, even in patients with other previous diagnoses.
authors.affiliation: Department of Post-Graduation, Master Program in Integrated Dentistry Science, University of Cuiabá, Avenida Manoel José de Arruda No. 3.100, 78050-000 Cuiabá, MT, Brazil.
authors.forename: Luiz Evaristo Ricci
authors.initials: LE
authors.lastname: Volpato
authors.affiliation: Department of Post-Graduation, Master Program in Integrated Dentistry Science, University of Cuiabá, Avenida Manoel José de Arruda No. 3.100, 78050-000 Cuiabá, MT, Brazil.
authors.forename: Maria Carmen Palma Faria
authors.initials: MC
authors.lastname: Volpato
authors.affiliation: Department of Post-Graduation, Master Program in Integrated Dentistry Science, University of Cuiabá, Avenida Manoel José de Arruda No. 3.100, 78050-000 Cuiabá, MT, Brazil.
authors.forename: Artur Aburad
authors.initials: AA
authors.lastname: de Carvalhosa
authors.affiliation: Department of Post-Graduation, Master Program in Integrated Dentistry Science, University of Cuiabá, Avenida Manoel José de Arruda No. 3.100, 78050-000 Cuiabá, MT, Brazil.
authors.forename: Vinicius Canavarros
authors.initials: VC
authors.lastname: Palma
authors.affiliation: Department of Post-Graduation, Master Program in Integrated Dentistry Science, University of Cuiabá, Avenida Manoel José de Arruda No. 3.100, 78050-000 Cuiabá, MT, Brazil.
authors.forename: Alvaro Henrique
authors.initials: AH
authors.lastname: Borges