title: Isolated horizontal positional nystagmus from a posterior fossa lesion.
abstract: Isolated vertigo with horizontal positional nystagmus as an impending sign of a central lesion has rarely been reported. Here we present neuro-otologic findings of patients with these clinical signs. Lesion overlays from 6 patients with ageotropic positional nystagmus revealed that the nodulus and vermis are common areas of injury. In contrast, 2 patients with geotropic positional nystagmus had cerebellar peduncle and lateral medullary lesions. These clinical findings suggest that vertigo with horizontal positional nystagmus, even in the absence of other initial neurological signs, may indicate a posterior fossa lesion, including that in the nodulus, vermis, and deep cerebellar structures.
authors.affiliation: Departments of Otorhinolaryngology.
authors.forename: Hyo-Jeong
authors.initials: HJ
authors.lastname: Lee
authors.forename: Eun Soo
authors.initials: ES
authors.lastname: Kim
authors.forename: Minbum
authors.initials: M
authors.lastname: Kim
authors.forename: Hosuk
authors.initials: H
authors.lastname: Chu
authors.forename: Hyeo-Il
authors.initials: HI
authors.lastname: Ma
authors.forename: Joong Seob
authors.initials: JS
authors.lastname: Lee
authors.forename: Ja-Won
authors.initials: JW
authors.lastname: Koo
authors.forename: Hyung-Jong
authors.initials: HJ
authors.lastname: Kim
authors.forename: Sung Kwang
authors.initials: SK
authors.lastname: Hong
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002528:Cerebellar Neoplasms / Q000150:complications* / Q000175:diagnosis*; D003388:Cranial Fossa, Posterior / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008526:Medulla Oblongata / Q000473:pathology; D008875:Middle Aged; D009759:Nystagmus, Pathologic / Q000175:diagnosis* / Q000209:etiology*; D014717:Vertigo / Q000175:diagnosis / Q000209:etiology; D055815:Young Adult