title: Possible effect of variable membrane potential of a cancer cell on different carcinogenic processes.
abstract: Cancer cells (unlike normal analogs) have a variable membrane potential on their surface, which depends on the intensity of metabolism of this type of cells and the environmental hydrogen index: in the case of low-pH (acid medium) they are known to have either a low negative or even positive charge, while in the case of high-pH (alkaline medium) - a relatively high negative charge. In this paper we suggest that the processes of metastasis, progression and invasion ongoing in a macro organism can be ascribed to the presence of exactly this variable electric charge in a cancer cell.
authors.affiliation: Tbilisi State Medical University, Georgia.
authors.forename: G
authors.initials: G
authors.lastname: Gogichadze
authors.affiliation: Tbilisi State Medical University, Georgia.
authors.forename: T
authors.initials: T
authors.lastname: Gogichadze
authors.affiliation: Tbilisi State Medical University, Georgia.
authors.forename: E
authors.initials: E
authors.lastname: Misabishvili
authors.affiliation: Tbilisi State Medical University, Georgia.
authors.forename: G
authors.initials: G
authors.lastname: Kamkamidze
mesh_terms: D063646:Carcinogenesis; D002462:Cell Membrane / Q000737:chemistry; D006801:Humans; D008564:Membrane Potentials; D009361:Neoplasm Invasiveness / Q000235:genetics; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000378:metabolism* / Q000473:pathology; D013499:Surface Properties