title: [Clinical features of oral lesions in patients with human immunodeficiency virus infection/acquired immunodeficiency syndrome in Guangxi autonomous region].
abstract: OBJECTIVE
  To investigate the features of oral lesions in patients with human immunodeficiency virus infection/acquired immunodeficiency syndrome (HIV/AIDS).
  
  
  METHODS
  A total of 127 HIV-seropositive patients were interviewed for health information and examined for their HIV-related oral lesions according to the EC Clearing House Criteria on Oral Problems related to HIV-Infection (1992). The examinations were conducted by dental specialist and HIV specialist. The CD4 T cell count in peripheral blood of the patients was tested by flow cytometry. The patients were divided into HIV- infected group (42) and AIDS group (85) according to CDC Classification System for HIV- Infected Adults and Adolescents (revised in 1993). Chi-square test was used to test the relationship between systemic disease and oral lesions, and the difference of the prevalence of oral lesions between the two groups.
  
  
  RESULTS
  Among the 127 patients, oral candidiasis (51/127), oral hairy leukoplakia (24/127) were common oral manifestation. There was no relationship between the oral manifestation and systemic disease (P = 0.397). The occurrence of oral lesions and oral candidiasis was significantly different between the two groups (χ² = 7.684, P = 0.006; χ² = 14.410, P < 0.001). The CD4 count was related to the prevalence of oral lesions (P = 0.006) and oral candidasis (P = 0.003).
  
  
  CONCLUSIONS
  Most oral lesions appeared before the appearance of systemic disease. Oral candidiasis and oral hairy leukoplakia were the most common lesions.Oral lesions had no relationship with systemic disease but could be still an indicator for disease progress.
authors.affiliation: Department of Periodontics and Oral Medicine, College of Stomatology, GuangXi Medical University, Nanning 530021, China.
authors.forename: Xiangzhi
authors.initials: X
authors.lastname: Yong
authors.affiliation: Department of Periodontics and Oral Medicine, College of Stomatology, GuangXi Medical University, Nanning 530021, China.
authors.forename: Lanlan
authors.initials: L
authors.lastname: Jiang
authors.affiliation: Department of Periodontics and Oral Medicine, College of Stomatology, GuangXi Medical University, Nanning 530021, China.
authors.forename: Xiangchan
authors.initials: X
authors.lastname: Lu
authors.affiliation: Department of Periodontics and Oral Medicine, College of Stomatology, GuangXi Medical University, Nanning 530021, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.affiliation: Department of Periodontics and Oral Medicine, College of Stomatology, GuangXi Medical University, Nanning 530021, China.
authors.forename: Nianning
authors.initials: N
authors.lastname: Wu
authors.affiliation: Department of Periodontics and Oral Medicine, College of Stomatology, GuangXi Medical University, Nanning 530021, China. Email: taorenchuan@gmail.com.
authors.forename: Renchuan
authors.initials: R
authors.lastname: Tao
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D018791:CD4 Lymphocyte Count; D015496:CD4-Positive T-Lymphocytes; D002180:Candidiasis, Oral / Q000453:epidemiology*; D002681:China / Q000453:epidemiology; D015658:HIV Infections; D006801:Humans; D017733:Leukoplakia, Hairy; D009059:Mouth Diseases / Q000150:complications / Q000453:epidemiology*; D015995:Prevalence