title: Ufmylation of ASC1 is essential for breast cancer development.
abstract: UFM1 modifies ASC1 to promote ERα transactivation and development of breast cancer.
mesh_terms: D001943:Breast Neoplasms / Q000378:metabolism*; D047628:Estrogen Receptor alpha / Q000378:metabolism*; D005260:Female; D006801:Humans; D011499:Protein Processing, Post-Translational; D011506:Proteins / Q000378:metabolism*; D014157:Transcription Factors / Q000378:metabolism*
chemical_list: C506487:ESR1 protein, human; D047628:Estrogen Receptor alpha; D011506:Proteins; C459901:TRIP4 protein, human; D014157:Transcription Factors; C502094:UFM1 protein, human