title: [Laser microdissection and mass spectrometry based proteomics in the diagnosis of kidney diseases].
abstract: In recent years, laser microdissection followed by mass spectrometry (LMD/MS) has been successfully applied to the proteomic studies of formalin-fixed paraffin-embedded (FFPE) renal tissues. This new technique improves the diagnosis of kidney diseases and has a better potential for future clinical application. The review focuses on the use of this methodology for exploring the mechanisms, diagnosis and classification of kidney diseases including renal amyloidosis and membrane proliferative glomerulonephritis.
authors.forename: Ying
authors.initials: Y
authors.lastname: Sun
authors.forename: Mingxi
authors.initials: M
authors.lastname: Li
authors.forename: Yubing
authors.initials: Y
authors.lastname: Wen
authors.forename: Xuemei
authors.initials: X
authors.lastname: Li
authors.forename: Jian
authors.initials: J
authors.lastname: Sun
authors.forename: Wei
authors.initials: W
authors.lastname: Sun
mesh_terms: D005557:Formaldehyde; D006801:Humans; D007668:Kidney / Q000473:pathology; D007674:Kidney Diseases / Q000175:diagnosis*; D061346:Laser Capture Microdissection; D013058:Mass Spectrometry; D040901:Proteomics; D016707:Tissue Fixation
chemical_list: D005557:Formaldehyde