title: Langerhans cell histiocytosis of the clavicle: a case report and review of the literature.
abstract: We report a rare case of solitary Langerhans cell histiocytosis (LCH) involving the clavicle of an adult female. The patient was a 32-year-old female presenting with 1 month history of progressive pain, swelling, and tenderness in the region near the left sternoclavicular joint. Radiograph, computed tomography, and magnetic resonance imaging showed an osteolytic lesion in the clavicle with tumor extension and soft tissue edema. Surgical curettage of the lesion was performed, and the histopathologic diagnosis was LCH. Because of its rarity and possibly variable presentation, LCH should be included and considered in the differential diagnosis when we encounter a clavicle lesion.
authors.affiliation: Department of Radiology (SW, WZ, LZ, ZL), First Affiliated Hospital of Dalian Medical University; and Department of Radiology (SN), Second People's Hospital of Dalian, Dalian, China.
authors.forename: Shaowu
authors.initials: S
authors.lastname: Wang
authors.forename: Weisheng
authors.initials: W
authors.lastname: Zhang
authors.forename: Shengbo
authors.initials: S
authors.lastname: Na
authors.forename: Lina
authors.initials: L
authors.lastname: Zhang
authors.forename: Zhijin
authors.initials: Z
authors.lastname: Lang
mesh_terms: D000328:Adult; D002968:Clavicle / Q000000981:diagnostic imaging / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D014057:Tomography, X-Ray Computed