title: Outcome after Computer-Assisted (Robotic) Nissen Fundoplication in Children Measured as Pre- and Postoperative Acid Reducing and Asthma Medications Use.
abstract: OBJECTIVE
  This study aims to report the clinical outcome of computer-assisted fundoplication (CAF) in children.
  
  
  METHODS
  As our center changed policy to using computer-assisted surgery only, a prospectively studied cohort of 40 children underwent CAF, during the period from January 2006 through May 2013. The collected data include patient demographics and postoperative complications as well as medication, 24-hour pH measurements and DeMeester scores before and after surgery.
  
  
  RESULTS
  In the studied group, the median percentage of the duration of the 24-hour pH < 4 decreased postoperatively from 11 (range, 5-39) to 1% (range, 0-12) (p < 0.001); the DeMeester score decreased from 40 (range, 17-137) to 5 (range, 1-42) (p < 0.001). All 40 patients required antireflux medication before the fundoplication. This number decreased significantly to 8 (20%) after the fundoplication (p < 0.001). Before the fundoplication, 22 children (55%) were using asthma medication and 12 (30%) after the fundoplication (p = 0.04).
  
  
  CONCLUSIONS
  The CAF significantly reduced the acid reflux from the stomach to the esophagus and the use of antireflux as well as asthma medication during the median observation period of 5 years. The evidence of advantages compared with conventional laparoscopic fundoplication remain to be confirmed.
authors.affiliation: Department of Pediatric Surgery, Skane University Hospital, Lund, Sweden.
authors.forename: Christina
authors.initials: C
authors.lastname: Granéli
authors.affiliation: Department of Pediatric Surgery, Skane University Hospital, Lund, Sweden.
authors.forename: Christina Clementson
authors.initials: CC
authors.lastname: Kockum
authors.affiliation: Department of Pediatric Surgery, Skane University Hospital, Lund, Sweden.
authors.forename: Einar
authors.initials: E
authors.lastname: Arnbjornsson
authors.affiliation: Department of Pediatric Surgery, Skane University Hospital, Lund, Sweden.
authors.forename: Magnus
authors.initials: M
authors.lastname: Anderberg
mesh_terms: D000293:Adolescent; D000863:Antacids / Q000627:therapeutic use*; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use*; D001249:Asthma / Q000150:complications / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D018662:Fundoplication / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000150:complications / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D065287:Robotic Surgical Procedures / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D000863:Antacids; D018927:Anti-Asthmatic Agents