title: Pattern of Viral Infections among Infants and Children Admitted to the Paediatric Intensive Care Unit at Sultan Qaboos University Hospital, Oman.
abstract: OBJECTIVE
  The aim of this study was to describe the pattern of viral infections in infants and children admitted to the Paediatric Intensive Care Unit (PICU) at Sultan Qaboos University Hospital (SQUH) in Muscat, Oman.
  
  
  METHODS
  A retrospective review of patient records was carried out on all patients admitted to the PICU between January 2011 and December 2012. In order to detect viruses, polymerase chain reaction (PCR) technology was used to detect viruses in nasopharyngeal aspirates, tracheal aspirates, plasma, stool and urine samples. All infants and children below 13 years old, who were admitted to the PICU at SQUH during the study period and with confirmed viral infections, were included in the study.
  
  
  RESULTS
  A total of 373 infants and children were admitted to the PICU during the study period. Viruses were detected in 34 patients. The most frequently detected viruses were cytomegalovirus (CMV) in 29.4%; this virus was noted predominantly in immuncompromised patients (80%, P = 0.023) and was associated with increased mortality (50%, P = 0.031) and prolonged PICU stay (70%, P = 0.045). Fatalities before discharge were recorded in 23.5% of the patients. The most frequent risk factors for viral infections were an age of <12 months old (47.1%), assisted ventilation/intubation (52.9%) and a prolonged PICU stay (55.9%).
  
  
  CONCLUSIONS
  The results of this study found that CMV was the most common viral infection among infants and children admitted to the PICU in SQUH. CMV was also the leading cause of mortality.
authors.affiliation: Departments of Child Health, Sultan Qaboos University Hospital, Muscat, Oman.
authors.forename: Anas-Alwogud A
authors.initials: AA
authors.lastname: Abdelmogheth
authors.affiliation: Departments of Child Health, Sultan Qaboos University Hospital, Muscat, Oman.
authors.forename: Alddai M A
authors.initials: AM
authors.lastname: Al-Nair
authors.affiliation: Medicine, Sultan Qaboos University Hospital, Muscat, Oman.
authors.forename: Abdullah A S
authors.initials: AA
authors.lastname: Balkhair
authors.affiliation: Departments of Child Health, Sultan Qaboos University Hospital, Muscat, Oman.
authors.forename: Akram M
authors.initials: AM
authors.lastname: Mahmoud
authors.affiliation: Departments of Child Health, Sultan Qaboos University Hospital, Muscat, Oman.
authors.forename: Mohamed
authors.initials: M
authors.lastname: El-Naggari
keywords: Children; Cytomegalovirus; Infants; Oman; Respiratory Syncytial Viruses; Viral Diseases; Viruses