title: Light-driven directed proton transport across the liposomal membrane.
abstract: We have developed a simple artificial photoresponsive ion-gating device by inserting molecular switches in the membrane of liposomes. A controlled and directed proton transport across the bilayer membrane can lower the internal pH of the liposomes from neutral to around 4 under combined light and chemical stimulation.
authors.affiliation: Dipartimento di Farmacia, Università degli Studi "Gabriele d'Annunzio" , Via dei Vestini, I-66100 Chieti, Italy.
authors.forename: Romina
authors.initials: R
authors.lastname: Zappacosta
authors.forename: Gabriella
authors.initials: G
authors.lastname: Siani
authors.forename: Serena
authors.initials: S
authors.lastname: Silvi
authors.forename: Alberto
authors.initials: A
authors.lastname: Credi
authors.forename: Antonella
authors.initials: A
authors.lastname: Fontana
mesh_terms: D006863:Hydrogen-Ion Concentration; D008027:Light; D008051:Lipid Bilayers / Q000737:chemistry*; D008081:Liposomes / Q000737:chemistry*; D015394:Molecular Structure; D010713:Phosphatidylcholines / Q000737:chemistry*; D011522:Protons
chemical_list: D008051:Lipid Bilayers; D008081:Liposomes; D010713:Phosphatidylcholines; D011522:Protons; C028694:1-palmitoyl-2-oleoylphosphatidylcholine