title: Human G3P[4] rotavirus obtained in Japan, 2013, possibly emerged through a human-equine rotavirus reassortment event.
abstract: Two novel G3P[4] rotavirus strains were detected from children with acute diarrhea in Sendai, Japan, identified as a G3-P[4]-I2-R2-C2-M2-A2-N2-T2-E2-H2 genotype constellation by whole-genome sequence analysis. The VP7 gene of the two strains displayed the highest nucleotide sequence identity (91 %) and showed a close genetic relationship (99 % bootstrap value) to an equine rotavirus reported in India. The other gene segments were related to human group A rotaviruses. This report suggests a possible reassortment event between human and equine rotaviruses.
authors.affiliation: Department of Virology, Tohoku University Graduate School of Medicine, Seiryo-cho 2-1, Aoba-ku, Sendai, Miyagi, 980-8575, Japan.
authors.forename: Rungnapa
authors.initials: R
authors.lastname: Malasao
authors.forename: Mayuko
authors.initials: M
authors.lastname: Saito
authors.forename: Akira
authors.initials: A
authors.lastname: Suzuki
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Imagawa
authors.forename: Nao
authors.initials: N
authors.lastname: Nukiwa-Soma
authors.forename: Kentaro
authors.initials: K
authors.lastname: Tohma
authors.forename: Xiaofang
authors.initials: X
authors.lastname: Liu
authors.forename: Michiko
authors.initials: M
authors.lastname: Okamoto
authors.forename: Natthawan
authors.initials: N
authors.lastname: Chaimongkol
authors.forename: Clyde
authors.initials: C
authors.lastname: Dapat
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Kawamura
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Kayama
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Masago
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Omura
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Oshitani
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000235:genetics; D036022:Capsid Proteins / Q000235:genetics; D002675:Child, Preschool; D016000:Cluster Analysis; D003967:Diarrhea / Q000453:epidemiology / Q000821:virology; D005260:Female; D006736:Horses; D006801:Humans; D007223:Infant; D007564:Japan / Q000453:epidemiology; D008297:Male; D008969:Molecular Sequence Data; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics*; D016865:Reassortant Viruses / Q000235:genetics* / Q000302:isolation & purification*; D012401:Rotavirus / Q000235:genetics* / Q000302:isolation & purification*; D012400:Rotavirus Infections / Q000453:epidemiology / Q000821:virology*; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid
chemical_list: D000956:Antigens, Viral; D036022:Capsid Proteins; D012367:RNA, Viral; C050779:VP7 protein, Rotavirus