title: Preparation of a monolith functionalized with zinc oxide nanoparticles and its application in the enrichment of fluoroquinolone antibiotics.
abstract: This study describes the enrichment ability of ZnO-modified methacrylic acid-co-ethylene dimethacrylate polymer monoliths as stationary phases for the simultaneous determination of antibiotics (ofloxacin, ciprofloxacin, enoxacin, and pefloxacin) combined with high-performance liquid chromatography. The prepared monolith was characterized by scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier-transformed infrared spectroscopy, and thermogravimetric analysis. The polymer monolith microextraction method has been applied to the enrichment of fluoroquinolone antibiotics and satisfactory results were obtained in the analysis of water samples. Compared with the conventional methacrylic acid based monolith, the developed monolith exhibited a higher enrichment capacity because of the introduction of zinc oxide into the preparation process.
authors.affiliation: College of Chemistry, Jilin University, Changchun, China.
authors.forename: Dan
authors.initials: D
authors.lastname: Liu
authors.forename: Jiutong
authors.initials: J
authors.lastname: Ma
authors.forename: Yan
authors.initials: Y
authors.lastname: Jin
authors.forename: Xiqian
authors.initials: X
authors.lastname: Li
authors.forename: Xiao
authors.initials: X
authors.lastname: Zhou
authors.forename: Qiong
authors.initials: Q
authors.lastname: Jia
authors.forename: Weihong
authors.initials: W
authors.lastname: Zhou
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D024841:Fluoroquinolones / Q000737:chemistry / Q000302:isolation & purification*; D053758:Nanoparticles / Q000737:chemistry; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*; D014874:Water Pollutants, Chemical / Q000737:chemistry / Q000302:isolation & purification; D015034:Zinc Oxide / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D014874:Water Pollutants, Chemical; D015034:Zinc Oxide
keywords: Fluoroquinolone; High-performance liquid chromatography; Monoliths; Zinc oxide