title: [Identification of hepatitis B virus intergenotype recombination in Chinese patients].
abstract: OBJECTIVE
  To identify the intergenotype recombination of hepatitis B virus (HBV) in Chinese patients and explore new recombination types of HBV.
  
  
  METHODS
  Complete genome sequences of HBV from Chinese patients were downloaded from GenBank and analyzed by Fragment-typing method to screen the potential recombinants, and the breakpoints of recombination were identified by using Simplot program.
  
  
  RESULTS
  Thirty-one recombination types including 755 recombinants were identified from 1642 complete HBV genome sequences, including 22 B/C recombination types with 676 recombinants, 5 C/D recombination types with 75 recombinants, 3 A/C recombination types with 3 recombinants, and 1 C/I recombination type with 1 recombinant.
  
  
  CONCLUSIONS
  Of the 31 recombination types comprising 755 recombinants, 4 are novel recombination types found for the first time. All these recombination types identified in this study involve genotype C.
authors.affiliation: Department of Infectious Diseases and Hepatology Unit, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.E-mail: chinapandeng@163.com.
authors.forename: Deng
authors.initials: D
authors.lastname: Pan
authors.forename: Bin
authors.initials: B
authors.lastname: Zhou
authors.forename: Jie
authors.initials: J
authors.lastname: Yang
authors.forename: Jinlin
authors.initials: J
authors.lastname: Hou
mesh_terms: D016679:Genome, Viral; D005838:Genotype; D006515:Hepatitis B virus / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D010802:Phylogeny; D011995:Recombination, Genetic