title: Comparison of select analytes in exhaled aerosol from e-cigarettes with exhaled smoke from a conventional cigarette and exhaled breaths.
abstract: Exhaled aerosols were collected following the use of two leading U.S. commercial electronic cigarettes (e-cigarettes) and a conventional cigarette by human subjects and analyzed for phenolics, carbonyls, water, glycerin and nicotine using a vacuum-assisted filter pad capture system. Exhaled breath blanks were determined for each subject prior to each product use and aerosol collection session. Distribution and mass balance of exhaled e-cigarette aerosol composition was greater than 99.9% water and glycerin, and a small amount (<0.06%) of nicotine. Total phenolic content in exhaled e-cigarette aerosol was not distinguishable from exhaled breath blanks, while total phenolics in exhaled cigarette smoke were significantly greater than in exhaled e-cigarette aerosol and exhaled breaths, averaging 66 µg/session (range 36 to 117 µg/session). The total carbonyls in exhaled e-cigarette aerosols were also not distinguishable from exhaled breaths or room air blanks. Total carbonyls in exhaled cigarette smoke was significantly greater than in exhaled e-cigarette aerosols, exhaled breath and room air blanks, averaging 242 µg/session (range 136 to 352 µg/session). These results indicate that exhaled e-cigarette aerosol does not increase bystander exposure for phenolics and carbonyls above the levels observed in exhaled breaths of air.
authors.affiliation: Lorillard Tobacco Company, P.O. Box 21688, Greensboro, NC 27420, USA. glong@lortobco.com.
authors.forename: Gerald A
authors.initials: GA
authors.lastname: Long
mesh_terms: D000328:Adult; D000336:Aerosols / Q000032:analysis*; D000393:Air Pollutants / Q000032:analysis*; D066300:Electronic Nicotine Delivery Systems; D006801:Humans; D008875:Middle Aged; D012906:Smoke / Q000032:analysis*; D062789:Tobacco Products / Q000032:analysis*; D055815:Young Adult
chemical_list: D000336:Aerosols; D000393:Air Pollutants; D012906:Smoke