title: Hyperandrogenism produced by ovarian tumors in women at different life stages.
abstract: OBJECTIVE
  to evaluate the different presentations of hyperandrogenism produced by ovarian tumors in women at different life stages
  
  
  METHODS
  case report.
  
  
  METHODS
  academic institutions.
  
  
  METHODS
  3 patients at different life stages, with increased androgen levels.
  
  
  METHODS
  review of hospital records.
  
  
  METHODS
  clinical and biochemical features, treatment and follow-up.
  
  
  RESULTS
  a 10 year-old girl with Leydig cell tumor presented with hyperandrogenemia, virilization and changes in social behavior. Another patient, at reproductive age, with a tumor>10 cm, presented with signs of virilization and abdominal mass, whose pathologic analysis disclosed a carcinoid tumor of the ovary associated with stromal hyperplasia. The third patient was a postmenopausal woman with severe alopecia, who presented a steroid cell tumor, rare at that age.
  
  
  CONCLUSIONS
  the evaluation of women with signs and symptoms of virilization should include a detailed clinical record, thorough physical examination and an appropriate hormonal dosage, especially when images are inconclusive.
authors.forename: Carolina
authors.initials: C
authors.lastname: Fux-Otta
authors.forename: Paula
authors.initials: P
authors.lastname: Szafryk de Mereshian
authors.forename: Mónica
authors.initials: M
authors.lastname: López de Corominas
authors.forename: Margarita
authors.initials: M
authors.lastname: Fuster
authors.forename: Carlos R
authors.initials: CR
authors.lastname: López
mesh_terms: D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D017588:Hyperandrogenism / Q000209:etiology*; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000150:complications*; D018312:Sex Cord-Gonadal Stromal Tumors / Q000150:complications*