title: Synthesis and Antibacterial Activities of Yanglingmycin Analogues.
abstract: The synthesis of Yanglingmycin and its enantiomer, along with eighteen Yanglingmycin analogues is reported. The structures were confirmed mainly by analyses of NMR spectral data. Antibacterial activity assays showed that Yanglingmycin and some of its analogues exhibited significant antibacterial activities against two important agricultural pathogenic bacteria, Ralstonia solanacearum and Pseudomonas syringae pv. actinidiae, with MIC values ranging from 3.91 to 15.62 μg/mL. The antibacterial activities exhibited by Yanglingmycin and its analogues are promising, suggesting potential in the development of compounds for novel bactericides.
authors.affiliation: College of Sciences, Northwest A & F University.
authors.forename: Long-Bo
authors.initials: LB
authors.lastname: Li
authors.forename: Wen-Jia
authors.initials: WJ
authors.lastname: Dan
authors.forename: Fang-Fang
authors.initials: FF
authors.lastname: Tan
authors.forename: Li-Hui
authors.initials: LH
authors.lastname: Cui
authors.forename: Zhi-Peng
authors.initials: ZP
authors.lastname: Yuan
authors.forename: Wen-Jun
authors.initials: WJ
authors.lastname: Wu
authors.forename: Ji-Wen
authors.initials: JW
authors.lastname: Zhang