title: Sequential harvesting of bone graft from the intramedullary canal of the femur.
abstract: The effectiveness of using the Reamer/Irrigator/Aspirator (RIA) System (Synthes, Inc, West Chester, Pennsylvania) to obtain bone graft from the intramedullary canal of long bones for the treatment of bone defects and nonunions has been previously documented. However, there is nothing in the literature discussing the potential for reaming the same canal at subsequent surgeries. The authors detail their experience of 8 instances of sequential reaming in 7 patients. Six patients were harvested twice, and 1 patient was harvested 3 times. In each patient, the bone graft was obtained from the same canal. The main outcome measurements were time interval between reamings, reamer head size, indication for reaming, volume of harvested bone graft, and complications. Average volume of graft obtained in the first reaming procedure was 34 mL (range, 25-50 mL). After an average of 9 months (range, 3-16 months), the subsequent reaming was performed. Average volume of graft obtained in the second procedure was 45 mL (range, 28-65 mL). In the authors' series, no reaming-related complications were observed. The graft volume was the same or increased during the subsequent intramedullary reaming in all but 1 case, suggesting that the intramedullary canal is a potentially renewable source for bone graft. There were no complications related to the sequential reaming procedure. Overall, the authors' data suggest that sequential reaming with the RIA has the potential to safely and effectively provide a large quantity of bone graft on multiple occasions.
authors.forename: Janet D
authors.initials: JD
authors.lastname: Conway
authors.forename: Lior
authors.initials: L
authors.lastname: Shabtai
authors.forename: Stacy C
authors.initials: SC
authors.lastname: Specht
authors.forename: John E
authors.initials: JE
authors.lastname: Herzenberg
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001847:Bone Diseases / Q000601:surgery*; D001862:Bone Resorption / Q000601:surgery*; D016025:Bone Transplantation / Q000379:methods*; D005260:Female; D005269:Femur / Q000637:transplantation*; D050723:Fractures, Bone / Q000150:complications / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D020858:Tissue and Organ Harvesting / Q000295:instrumentation*; D055815:Young Adult