title: Near-infrared fundus autofluorescence in multiple evanescent white-dot syndrome.
abstract: OBJECTIVE
  To report the near-infrared fundus autofluorescence (NIR-FAF) pattern in 2 cases of multiple evanescent white-dot syndrome (MEWDS).
  
  
  METHODS
  Three consecutive patients with MEWDS underwent a complete ophthalmologic examination, including color photograph, blue-light fundus autofluorescence, NIR-FAF, fluorescein angiography, and indocyanine green angiography (ICGA). Main outcome measure was the identification of NIR-FAF pattern.
  
  
  RESULTS
  Fluorescein angiography showed patchy hyperfluorescence of the whitish dots. Indocyanine green angiography showed hypofluorescent spots throughout the examination. Blue-light fundus autofluorescence disclosed a speckled pattern without extension to the foveal area, whereas NIR-AF showed several hypoautofluorescent lesions involving also the fovea, which corresponded to the whitish dots visible on biomicroscopy and to the hypofluorescent lesions detectable on ICGA.
  
  
  CONCLUSIONS
  Near-infrared fundus autofluorescence is characterized by hypoautofluorescent spots corresponding to the inflammatory lesions typical of MEWDS and can be considered as a valuable noninvasive technique to diagnose and monitor patients with MEWDS.
authors.affiliation: Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele, Milan - Italy.
authors.forename: Maurizio
authors.initials: M
authors.lastname: Battaglia Parodi
authors.forename: Pierluigi
authors.initials: P
authors.lastname: Iacono
authors.forename: Bruno
authors.initials: B
authors.lastname: Falcomatà
authors.forename: Gianluigi
authors.initials: G
authors.lastname: Bolognesi
authors.forename: Francesco
authors.initials: F
authors.lastname: Bandello
mesh_terms: D000293:Adolescent; D000328:Adult; D004596:Electroretinography; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D007259:Infrared Rays; D008297:Male; D008875:Middle Aged; D061848:Optical Imaging; D012164:Retinal Diseases / Q000175:diagnosis*; D055213:Retinal Pigment Epithelium / Q000473:pathology*; D013577:Syndrome; D041623:Tomography, Optical Coherence