title: Influence of sex on outcomes after percutaneous coronary intervention in patients over 75 years of age with coronary heart disease.
abstract: BACKGROUND
  This study aimed to investigate whether there were sex differences in in-hospital and long-term outcomes for elderly patients over 75 years of age undergoing percutaneous coronary intervention for coronary heart disease.
  
  
  METHODS
  Consecutive patients aged ≥75 years who underwent percutaneous coronary intervention at a single center in the People's Republic of China from January 2005 to December 2010 were included in this cohort study. Clinical characteristics and in-hospital and long-term outcomes were compared between men and women.
  
  
  RESULTS
  A total of 465 patients (34.8% women, mean age 78.5±3.2 years) were recruited. Men had a higher prevalence of ST elevation myocardial infarction but were less likely to have heart failure than women (P<0.05). Similar rates of successful in-hospital procedures and deaths were observed in men and women. After a mean follow-up of 3 years, no significant differences were observed between men and women in mortality (12.5% versus 8.0%, P=0.151), myocardial infarction (1.4% versus 2.7%, P=0.368), target vessel revascularization (6.1% versus 4.7%, P=0.540), or cerebral vascular disease (7.9% versus 6.0%, P=0.472). Cox proportional hazards analysis revealed that sex was not independently associated with either in-hospital mortality or long-term mortality.
  
  
  CONCLUSIONS
  In elderly patients over 75 years of age, sex influences the prognosis after percutaneous coronary intervention for coronary heart disease.
authors.affiliation: Institute of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, People's Republic of China.
authors.forename: Yuqi
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Institute of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, People's Republic of China.
authors.forename: Xin
authors.initials: X
authors.lastname: Hu
authors.affiliation: Institute of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, People's Republic of China.
authors.forename: Qiao
authors.initials: Q
authors.lastname: Xue
authors.affiliation: Institute of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, People's Republic of China.
authors.forename: Yusheng
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Institute of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, People's Republic of China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Institute of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, People's Republic of China.
authors.forename: Lei
authors.initials: L
authors.lastname: Gao
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary; D002423:Cause of Death; D002681:China; D015331:Cohort Studies; D003327:Coronary Disease / Q000401:mortality / Q000628:therapy*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D016016:Proportional Hazards Models; D012737:Sex Factors; D015996:Survival Rate
keywords: elderly; percutaneous coronary intervention; sex