title: Ovarian Hormone Influences on Dysregulated Eating: A Comparison of Associations in Women with versus without Binge Episodes.
abstract: Changes in ovarian hormones predict changes in emotional eating across the menstrual cycle. However, prior studies have not examined whether the nature of associations varies across dysregulated eating severity. The current study determined whether the strength and/or nature of hormone/dysregulated eating associations differ based on the presence of clinically diagnosed binge episodes (BEs). Participants included 28 women with BEs and 417 women without BEs who provided salivary hormone samples, ratings of emotional eating, and BE frequency for 45 days. Results revealed stronger associations between dysregulated eating and ovarian hormones in women with BEs as compared to women without BEs. The nature of associations also differed, as progesterone moderated the effects of lower estradiol levels on dysregulated eating in women with BEs only. Although hormone/dysregulated eating associations are present across the spectrum of pathology, the nature of associations may vary in ways that have implications for etiological models and treatment.
authors.affiliation: Department of Psychology, Michigan State University.
authors.forename: Kelly L
authors.initials: KL
authors.lastname: Klump
authors.affiliation: Department of Psychiatry, University of Pittsburgh School of Medicine.
authors.forename: Sarah E
authors.initials: SE
authors.lastname: Racine
authors.affiliation: Department of Psychology, Michigan State University.
authors.forename: Britny
authors.initials: B
authors.lastname: Hildebrandt
authors.affiliation: Department of Psychology, Michigan State University.
authors.forename: S Alexandra
authors.initials: SA
authors.lastname: Burt
authors.affiliation: Department of Psychiatry, Human Genetics, and Psychology, Virginia Commonwealth University.
authors.forename: Michael
authors.initials: M
authors.lastname: Neale
authors.affiliation: Department of Psychology, Michigan State University ; Department of Neuroscience Program, Michigan State University.
authors.forename: Cheryl L
authors.initials: CL
authors.lastname: Sisk
authors.affiliation: Department of Psychology, University of Virginia.
authors.forename: Steven
authors.initials: S
authors.lastname: Boker
authors.affiliation: Department of Psychology, Florida State University.
authors.forename: Pamela K
authors.initials: PK
authors.lastname: Keel
keywords: binge eating; emotional eating; estrogen; ovarian hormones; progesterone