title: Cell-imprinted antimicrobial bionanomaterials with tolerable toxic side effects.
abstract: Taking advantage of imprinting technology, artificial antibody-microbial imprinted Ag-TiO(2) materials are fabricated for microbial inactivation using a facile and green method. Due to the induced shape and size recognition elements, the artificial antibodies specifically recognize and kill target microbes under visible-light irradiation with minimal toxic side effects toward mammalian cells.
authors.affiliation: Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry, State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, China; University of Chinese Academy of Sciences, Beijing, 100039, China.
authors.forename: Zhijun
authors.initials: Z
authors.lastname: Zhang
authors.forename: Meng
authors.initials: M
authors.lastname: Li
authors.forename: Jinsong
authors.initials: J
authors.lastname: Ren
authors.forename: Xiaogang
authors.initials: X
authors.lastname: Qu
mesh_terms: D000906:Antibodies / Q000276:immunology / Q000648:ultrastructure*; D000935:Antifungal Agents / Q000009:adverse effects / Q000737:chemistry / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects; D057809:HEK293 Cells; D006801:Humans; D008422:Materials Testing; D053768:Metal Nanoparticles / Q000008:administration & dosage* / Q000737:chemistry / Q000648:ultrastructure*; D054802:Molecular Imprinting / Q000379:methods*; D012441:Saccharomyces cerevisiae / Q000187:drug effects; D012834:Silver / Q000009:adverse effects / Q000737:chemistry / Q000494:pharmacology*; D013499:Surface Properties; D014025:Titanium / Q000009:adverse effects / Q000737:chemistry
chemical_list: D000906:Antibodies; D000935:Antifungal Agents; C009495:titanium dioxide; D012834:Silver; D014025:Titanium
keywords: Ag-TiO2 composites; antimicrobial; artificial antibodies; molecular imprinting; photocatalysis