title: Calcified telangiectatic hyperplastic nodule associated with vascular malformation in a child: a case report.
abstract: This is a case report of an asymptomatic 4-year-old girl who was found to have a nodule at the lateral left lobe of the liver. She underwent transabdominal liver ultrasound and abdominal MRI that showed calcification and intense arterial enhancement but they failed to clearly exclude malignancy. The patient underwent an unremarkable laparoscopic wedge liver resection of the lesion because of its location and size. Pathological examination showed features compatible with a benign telangiectatic hyperplastic nodule with vascular malformation and calcification. CD34 immunostained the proliferative vascular lining cells while CK7 and CK19 highlighted the normal bile ducts present within the lesion. The diagnosis of a telangiectatic hyperplastic nodule associated with vascular malformation has been scarcely reported in children and our case shows for the first time that it can also present with calcifications.
authors.affiliation: 1Mount Sinai Medical Center, Recanati-Miller Transplant Institute , New York, NY , USA.
authors.forename: Josep
authors.initials: J
authors.lastname: Marti
authors.forename: Anshu
authors.initials: A
authors.lastname: Trivedi
authors.forename: Valentina
authors.initials: V
authors.lastname: D'Alessandro
authors.forename: Sasan
authors.initials: S
authors.lastname: Roayaie
authors.forename: Ally
authors.initials: A
authors.lastname: Rosen
authors.forename: Ronen
authors.initials: R
authors.lastname: Arnon
authors.forename: Swan
authors.initials: S
authors.lastname: Thung
mesh_terms: D049109:Cell Proliferation / Q000502:physiology; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000000981:diagnostic imaging / Q000601:surgery; D008113:Liver Neoplasms / Q000098:blood supply / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*; D008279:Magnetic Resonance Imaging / Q000379:methods; D016896:Treatment Outcome; D014463:Ultrasonography; D054079:Vascular Malformations / Q000175:diagnosis / Q000473:pathology*
keywords: calcifications; focal nodular hyperplasia; pediatric liver tumor; telangiectatic hyperplasia; vascular malformation