title: Relation of mean platelet volume and red blood cell distribution width with epistaxis.
abstract: OBJECTIVE
  Mean platelet volume is the measurement of the average size of platelets in the blood, and red blood cell distribution width is the variability of the size of red blood cells in circulation. This study aimed to investigate if there was any relationship between mean platelet volume, red blood cell distribution, and epistaxis.
  
  
  METHODS
  Prospective controlled trial.
  
  
  METHODS
  The study included 90 patients admitted to Ankara Atatürk Hospital and Samsun Medicana Hospital with complaints of recurrent epistaxis, and a control group of 90 healthy subjects. Blood samples were taken from all patients and control group subjects. Mean platelet volume and red blood cell distribution parameters were examined and compared between the two groups.
  
  
  RESULTS
  The mean platelet volume levels were determined as 8.86 ± 0.1 in the control group and 8.36 ± 0.1 in the patient group. The difference between the two groups with respect to mean platelet volume was statistically significant (P < .05). The mean red blood cell distribution levels were determined as 12.68 ± 0.32 in the control group and 11.90 ± 0.16 in the patient group. The difference between the two groups with respect to red blood cell distribution was also statistically significant (P < .05).
  
  
  CONCLUSIONS
  The results of this study showed a clinical finding of lower mean platelet volume and red blood cell distribution levels in epistaxis. These findings could be beneficial in new investigations into epistaxis mechanisms.
authors.affiliation: Otolaryngology Department, Faculty of Medicine, Ondokuz Mayis University, Samsun.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Kemal
authors.forename: Togay
authors.initials: T
authors.lastname: Müderris
authors.forename: Ergün
authors.initials: E
authors.lastname: Sevil
authors.forename: Gökhan
authors.initials: G
authors.lastname: Kutlar
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D004844:Epistaxis / Q000097:blood* / Q000503:physiopathology*; D004906:Erythrocyte Count; D004909:Erythrocyte Indices / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume; D011379:Prognosis; D011446:Prospective Studies; D012016:Reference Values; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D014421:Turkey; D055815:Young Adult
chemical_list: D015415:Biomarkers
keywords: Mean platelet volume; epistaxis; red blood cell distribution