title: Nuclear physics (of the cell, not the atom).
abstract: The nucleus is physically distinct from the cytoplasm in ways that suggest new ideas and approaches for interrogating the operation of this organelle. Chemical bond formation and breakage underlie the lives of cells, but as this special issue of Molecular Biology of the Cell attests, the nonchemical aspects of cell nuclei present a new frontier to biologists and biophysicists.
authors.affiliation: Program in Cell and Developmental Dynamics, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605 thoru.pederson@umassmed.edu john-marko@northwestern.edu.
authors.forename: Thoru
authors.initials: T
authors.lastname: Pederson
authors.affiliation: Department of Molecular Biosciences and Department of Physics and Astronomy, Northwestern University, Evanston, IL 60208 thoru.pederson@umassmed.edu john-marko@northwestern.edu.
authors.forename: John F
authors.initials: JF
authors.lastname: Marko
mesh_terms: D000818:Animals; D001703:Biophysics / Q000295:instrumentation / Q000379:methods*; D002467:Cell Nucleus / Q000737:chemistry* / Q000378:metabolism / Q000648:ultrastructure; D002875:Chromosomes / Q000737:chemistry* / Q000378:metabolism; D003593:Cytoplasm / Q000737:chemistry / Q000378:metabolism; D004247:DNA / Q000737:chemistry / Q000378:metabolism; D005057:Eukaryotic Cells / Q000737:chemistry* / Q000378:metabolism / Q000648:ultrastructure; D006801:Humans; D009687:Nuclear Proteins / Q000737:chemistry / Q000378:metabolism; D012313:RNA / Q000737:chemistry / Q000378:metabolism; D014961:X-Ray Diffraction
chemical_list: D009687:Nuclear Proteins; D012313:RNA; D004247:DNA