title: The quantified cell.
abstract: The microscopic world of a cell can be as alien to our human-centered intuition as the confinement of quarks within protons or the event horizon of a black hole. We are prone to thinking by analogy-Golgi cisternae stack like pancakes, red blood cells look like donuts-but very little in our human experience is truly comparable to the immensely crowded, membrane-subdivided interior of a eukaryotic cell or the intricately layered structures of a mammalian tissue. So in our daily efforts to understand how cells work, we are faced with a challenge: how do we develop intuition that works at the microscopic scale?
authors.affiliation: Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720.
authors.forename: Avi
authors.initials: A
authors.lastname: Flamholz
authors.affiliation: Department of Applied Physics and Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125.
authors.forename: Rob
authors.initials: R
authors.lastname: Phillips
authors.affiliation: Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot 76100, Israel ron.milo@weizmann.ac.il.
authors.forename: Ron
authors.initials: R
authors.lastname: Milo
mesh_terms: D008841:Actin Cytoskeleton / Q000737:chemistry* / Q000378:metabolism; D000199:Actins / Q000737:chemistry* / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002465:Cell Movement; D005057:Eukaryotic Cells / Q000737:chemistry* / Q000166:cytology / Q000502:physiology; D006801:Humans; D008954:Models, Biological; D008970:Molecular Weight; D058105:Polymerization; D012333:RNA, Messenger / Q000737:chemistry* / Q000378:metabolism
chemical_list: D000199:Actins; D012333:RNA, Messenger; D000255:Adenosine Triphosphate