title: Precocious pseudopuberty due to ovarian causes.
abstract: BACKGROUND
  It is important to differentiate central from peripheral causes of precocious puberty because of distinct management options.
  
  
  METHODS
  4 girls with discordant pubertal development.
  
  
  METHODS
  All had low basal and GnRHa stimulated FSH and LH level with high estradiol level. Abdominal ultrasonogram helped in diagnosing precocious pseudopuberty- ovarian cyst in 3 children and juvenile granulosa cell tumour in one.
  
  
  RESULTS
  Case 1 and 4 underwent surgery in view of persistent cyst and tumor, respectively. Rest were managed conservatively. Regression of pubertal signs observed in all children during follow-up.
  
  
  CONCLUSIONS
  Precocious pseudopuberty can be differentiated from central precocious puberty by GnRHa Stimulation test, bone age and abdominal ultrasound.
authors.affiliation: Departments of Pediatric Endocrinology and *Pediatrics, Manipal Hospital, Bengaluru, India. Correspondence to: Dr J Dhivyalakshmi, C/o Dr. A. Karunagaran, 60/39, Model Hutment Road, CIT Nagar, Nandanam, Chennai 600 035, Tamilnadu, India.
authors.forename: Jeevarathnam
authors.initials: J
authors.lastname: Dhivyalakshmi
authors.forename: Shaila
authors.initials: S
authors.lastname: Bhattacharyya
authors.forename: Rajeshwari
authors.initials: R
authors.lastname: Reddy
authors.forename: K I
authors.initials: KI
authors.lastname: Arulselvi
mesh_terms: D002675:Child, Preschool; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007223:Infant; D007986:Luteinizing Hormone / Q000097:blood; D010048:Ovarian Cysts / Q000150:complications / Q000175:diagnosis; D011629:Puberty, Precocious / Q000175:diagnosis / Q000209:etiology
chemical_list: D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone