title: "Nanorust"-catalyzed benign oxidation of amines for selective synthesis of nitriles.
abstract: Organic nitriles constitute key precursors and central intermediates in organic synthesis. In addition, nitriles represent a versatile motif found in numerous medicinally and biologically important compounds. Generally, these nitriles are synthesized by traditional cyanation procedures using toxic cyanides. Herein, we report the selective and environmentally benign oxidative conversion of primary amines for the synthesis of structurally diverse aromatic, aliphatic and heterocyclic nitriles using a reusable "nanorust" (nanoscale Fe2 O3 )-based catalysts applying molecular oxygen.
authors.affiliation: Leibniz-Institut für Katalyse e. V. an der Universität Rostock, Albert-Einstein-Str. 29a, 18059 Rostock (Germany).
authors.forename: Rajenahally V
authors.initials: RV
authors.lastname: Jagadeesh
authors.forename: Henrik
authors.initials: H
authors.lastname: Junge
authors.forename: Matthias
authors.initials: M
authors.lastname: Beller
mesh_terms: D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D060326:Chemistry Techniques, Synthetic; D055772:Green Chemistry Technology; D008958:Models, Molecular; D008968:Molecular Conformation; D049329:Nanostructures / Q000737:chemistry*; D009570:Nitriles / Q000138:chemical synthesis* / Q000737:chemistry*; D010084:Oxidation-Reduction
chemical_list: D000588:Amines; D009570:Nitriles
keywords: amines; catalysis; iron; nitriles; oxidations