title: Case-Series Evaluating a Transdiagnostic Cognitive-Behavioural Treatment for Co-occurring Anxiety Disorders.
abstract: BACKGROUND
  Patients with anxiety disorder diagnoses commonly have more than one anxiety diagnosis. While cognitive-behavioural interventions have proven efficacy in treating single anxiety disorder diagnoses, there has been little investigation of their efficacy in treating co-occurring anxiety disorders.
  
  
  OBJECTIVE
  To evaluate the efficacy of a transdiagnostic cognitive-behavioural intervention for treating co-occurring anxiety disorders.
  
  
  METHODS
  An A-B single case study design (N = 6) was used to evaluate the efficacy of a 12 to 13-session modular transdiagnostic cognitive-behavioural intervention for treating co-occurring anxiety disorders across patients with at least two of the following diagnoses: GAD, Social Phobia, Panic Disorder and/or OCD.
  
  
  RESULTS
  Five of the six participants completed treatment. At posttreatment assessment the five treatment completers achieved diagnostic and symptomatic change, with three participants being diagnosis free. All participants who completed treatment no longer met criteria for any DSM-IV-TR Axis-I diagnosis at the 3-month follow-up assessment, and demonstrated reliable and clinically-significant improvements in symptoms. Across the participants, statistically significant improvements from pre to postintervention were found on measures of anxiety, depression and general well-being, and all improvements were maintained at 3-month follow-up.
  
  
  CONCLUSIONS
  Results suggest that transdiagnostic cognitive behavioural interventions can be of benefit to patients with co-occurring anxiety disorders.
authors.affiliation: University of Stirling,Scotland.
authors.forename: Freda
authors.initials: F
authors.lastname: McManus
authors.affiliation: University of New England,Australia.
authors.forename: Gavin
authors.initials: G
authors.lastname: Clark
authors.affiliation: University of Worcester,UK.
authors.forename: Kate
authors.initials: K
authors.lastname: Muse
authors.affiliation: UCL Institute of Child Health,London.
authors.forename: Roz
authors.initials: R
authors.lastname: Shafran
mesh_terms: D000328:Adult; D001008:Anxiety Disorders / Q000523:psychology / Q000628:therapy*; D016022:Case-Control Studies; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D015897:Comorbidity; D005260:Female; D006801:Humans; D008297:Male; D057566:Self Report; D016896:Treatment Outcome
keywords: Anxiety disorder; case-series; co-morbid; cognitive behavioural treatment; transdiagnostic