title: Visible-light-driven difluoroacetamidation of unactive arenes and heteroarenes by direct C-H functionalization at room temperature.
abstract: The directed difluoroacetamidation of unactivated arenes and heteroarenes with bromodifluoroacetamides via visible-light photoredox catalysis has been efficiently achieved at room temperature. Broad utility of this transformation is presented, including electronically deficient heteroaromatic and aromatic systems. The mechanistic pathway of the difluoroacetamidation was discussed based on photoluminescence quenching, spin-trapping, and kinetic isotope effect experiments.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University , 222 South Tianshui Road, Lanzhou 730000, P. R. China.
authors.forename: Lin
authors.initials: L
authors.lastname: Wang
authors.forename: Xiao-Jing
authors.initials: XJ
authors.lastname: Wei
authors.forename: Wen-Liang
authors.initials: WL
authors.lastname: Jia
authors.forename: Jian-Ji
authors.initials: JJ
authors.lastname: Zhong
authors.forename: Li-Zhu
authors.initials: LZ
authors.lastname: Wu
authors.forename: Qiang
authors.initials: Q
authors.lastname: Liu