title: Application of lumbar drainage in vasospasm after spontaneous subarachnoid hemorrhage and prevention of late cerebral infarction.
abstract: Cerebral vasospasm, especially delayed cerebral ischemia following subarachnoid hemorrhage (SAH) is the most important complication that effects mortality and morbidity of patients with intracranial aneurysms. The presence of cerebral vasospasm has been correlated with an increase in mortality in the first 2 weeks after SAH. Despite clinical studies and research, the etiopathogenesis of cerebral vasospasm is not understood exactly and there is not yet an effective therapy. The aim of our study was to investigate the effect of application of lumber drainage on vasospasm and delayed cerebral infarction following SAH and to examine the incidence of complications. Patient groups were determined by retrospective screening of 70 patients who underwent a surgical operation at the Osmangazi University Medical Faculty Department of Neurosurgery between 2009 and 2013 after a diagnosis of ruptured aneurysmal SAH. After the application of lumbar drainage, the complications and mortality after aneurysm surgery was significantly decreased and correlated with the amount of hemorrhagic cerebrospinal fluid drainage.
authors.affiliation: Department of Neurosurgery, Osmangazi University, Medical Faculty, Eskisehir, 26480, Turkey, dremreaydin@gmail.com.
authors.forename: Hasan Emre
authors.initials: HE
authors.lastname: Aydin
authors.forename: Zühtü
authors.initials: Z
authors.lastname: Ozbek
authors.forename: Nevin
authors.initials: N
authors.lastname: Aydin
authors.forename: Ozge
authors.initials: O
authors.lastname: Bolluk
authors.forename: Murat
authors.initials: M
authors.lastname: Vural
authors.forename: Ali
authors.initials: A
authors.lastname: Arslantas
authors.forename: Metin Ant
authors.initials: MA
authors.lastname: Atasoy
mesh_terms: D002544:Cerebral Infarction / Q000209:etiology / Q000401:mortality / Q000517:prevention & control*; D004322:Drainage / Q000379:methods*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000401:mortality / Q000517:prevention & control; D019586:Intracranial Hypertension / Q000209:etiology / Q000401:mortality / Q000517:prevention & control; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013129:Spinal Puncture / Q000379:methods*; D013345:Subarachnoid Hemorrhage / Q000150:complications / Q000401:mortality / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome; D020301:Vasospasm, Intracranial / Q000209:etiology / Q000401:mortality / Q000628:therapy*