title: [Application of narrow-band imaging endoscopy in laryngeal malignant lesion biopsy].
abstract: OBJECTIVE
  To investigate the guiding role of narrow-band imaging endoscopy in laryngeal malignant lesion biopsy.
  
  
  METHODS
  From February 2013 to January 2014, 113 patients suspected of laryngeal malignant lesions after electronic nasopharyngolaryngoscope screening were included in the study. The patients were randomly divided into two groups, 58 cases in group A underwent laryngeal tumor biopsies in the white light mode and 55 cases in group B did in NBI mode. The patients were applied with corresponding surgery treatment according to the biopsy results. Postoperative pathologic examination result was as a gold standard for identifing the laryngeal diseases.
  
  
  RESULTS
  The positive rate of malignant lesions in group A (71.1%, 32/45) was significantly lower than that in group B (95.4%, 42/44) (χ² = 7.75, P < 0.05); the accurate rate of biopsy in group A (77.6%, 45/58) was significantly lower than that in group B (96.4%, 53/55, χ² = 7.09, P < 0.05) .
  
  
  CONCLUSIONS
  Narrow-band imaging endoscopy can obviously improve in the detection of laryngeal malignant lesion by biopsy.
authors.affiliation: Tianjin Medical University, Tianjin 300070, China.
authors.forename: Xiaoyi
authors.initials: X
authors.lastname: Yang
authors.forename: Lin
authors.initials: L
authors.lastname: Wang
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Tianjin. Email: jixiangliu6@hotmail.com.
authors.forename: Jixiang
authors.initials: J
authors.lastname: Liu
mesh_terms: D001706:Biopsy / Q000379:methods; D004724:Endoscopy / Q000379:methods*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000601:surgery; D007828:Laryngoscopy; D007831:Larynx, Artificial