title: Extracorporeal membrane oxygenation treatment for H1N1-induced acute respiratory distress syndrome (ARDS): results of the Croatian Referral Center for Respiratory ECMO.
abstract: BACKGROUND
  Extracorporeal membrane oxygenation (ECMO) has been effective in the treatment of H1N1-induced ARDS across the globe. However, the evidence supporting the use of ECMO in ARDS is still being collected. The intention of this study was to add a piece of puzzle to the growing body of evidence on the use of ECMO in ARDS patients.
  
  
  METHODS
  The study included adult patients with H1N1-induced ARDS treated with ECMO at the University Hospital for Infectious Diseases in Zagreb, Croatia between October 2009 and December 2013.
  
  
  RESULTS
  17 patients with H1N1-induced ARDS treated with ECMO were included in the study. The patient cohort of the study was young with a median age of 43 years (range 23-74). The hospital mortality was 35%. Possible variables associated with mortality were analyzed and only hemolysis was found to be significant.
  
  
  CONCLUSIONS
  Our results confirm the usefulness of ECMO treatment in patients with H1N1-induced ARDS.
authors.affiliation: 1 Department of Intensive Care Medicine and Neuroinfectology, Dr. Fran Mihaljevic University Hospital for Infectious Diseases, University of Zagreb - School of Medicine, Zagreb - Croatia.
authors.forename: Marko
authors.initials: M
authors.lastname: Kutleša
authors.forename: Anda
authors.initials: A
authors.lastname: Novokmet
authors.forename: Renata
authors.initials: R
authors.lastname: Josipovic Mraovic
authors.forename: Boris
authors.initials: B
authors.lastname: Filar
authors.forename: Petar
authors.initials: P
authors.lastname: Mardešic
authors.forename: Bruno
authors.initials: B
authors.lastname: Baršic
mesh_terms: D000328:Adult; D000368:Aged; D017523:Croatia; D015199:Extracorporeal Membrane Oxygenation / Q000379:methods*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000150:complications* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D012128:Respiratory Distress Syndrome / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D016896:Treatment Outcome; D055815:Young Adult