title: An in situ generated achiral Cu(II)-containing polymer complex sensor for enantioselective recognition induced from L-/D-histidine enantiomers.
abstract: A novel achiral polymer P-1 is synthesized by the polymerization of (2,5-bis(octyloxy)-1,4-phenylene)diboronic acid (M-1) with pyridine-2,6-diylbis(methanylylidene)bis(4-iodoaniline) (M-2) via Pd-catalyzed Suzuki coupling reaction. The tridentate ligand in the main chain backbone can further coordinate with Cu(2+) to afford the corresponding achiral copper-containing polymer complex P-2, which selectively responds to L-/D-histidine with significant fluorescence enhancement over other amino acids. Interestingly, P-2 exhibits obvious CD response toward L- or D-histidine compared with its model compound MC, indicating that this kind Cu(II)-containing polymer complex sensor can be used as an effective chemosensor for enantioselective recognition of histidine enantiomers by means of CD spectroscopy.
authors.affiliation: Key Laboratory of Mesoscropic Chemistry of MOE, School of Chemistry and Chemical engineering, Nanjing University, No. 22, Hankou Road, Nanjing, 210093, China.
authors.forename: Guo
authors.initials: G
authors.lastname: Wei
authors.forename: Fandian
authors.initials: F
authors.lastname: Meng
authors.forename: Yuxiang
authors.initials: Y
authors.lastname: Wang
authors.forename: Yixiang
authors.initials: Y
authors.lastname: Cheng
authors.forename: Chengjian
authors.initials: C
authors.lastname: Zhu
mesh_terms: D002942:Circular Dichroism; D003300:Copper / Q000737:chemistry*; D006639:Histidine / Q000737:chemistry*; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013237:Stereoisomerism
chemical_list: D011108:Polymers; D006639:Histidine; D003300:Copper
keywords: CD spectra; copper-containing polymer complex; enantioselectivity; histidine; molecular recognition