title: [Granulomatous interstitial lung diseases].
abstract: Sarcoidosis is sometimes severe and, in this setting, some investigations like thoracic computed tomography and pulmonaruy function tests constitute an angular stone. In 25% of cases, the presentation is not typical and diagnosis may be difficult. Some lung granulomatosis may share a very similar presentation with sarcoidosis according to clinic, imaging, serum biology, broncho-alveolar lavage and pathology (berylliosis, immuno-deficiency and drug- induced lung granulomatosis). Eventually, lung Langerhans histiocytosis is a very rare disease observed in young adults with heavy smoking habits and thoracic CT is the crucial investigation to reach diagnosis in 80% of cases.
authors.forename: Dominique
authors.initials: D
authors.lastname: Valeyre
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Musungayi
mesh_terms: D000328:Adult; D015769:Granuloma, Respiratory Tract / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications / Q000175:diagnosis; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D017565:Sarcoidosis, Pulmonary / Q000150:complications / Q000175:diagnosis / Q000628:therapy