title: Significant publications on infectious diseases pharmacotherapy in 2013.
abstract: OBJECTIVE
  The most important articles on infectious diseases (ID) pharmacotherapy published in the peer-reviewed literature in 2013, as nominated and selected by panels of pharmacists and others with ID expertise, are summarized.
  
  
  CONCLUSIONS
  Members of the Houston Infectious Diseases Network were asked to nominate articles published last year in prominent biomedical journals that had a major impact in the field of ID pharmacotherapy. A list of 27 nominated articles on ID-related topics in general and 26 articles specifically focused on human immunodeficiency virus (HIV) infection or acquired immunodeficiency syndrome (AIDS) was compiled. In a national online survey conducted in January 2014, members of the Society of Infectious Diseases Pharmacists (SIDP) were asked to select from the list those articles that they felt had made the greatest contributions to the field of ID pharmacotherapy. Of 168 SIDP members surveyed, 108 (64%) and 53 (32%) participated in the selection of ID- and HIV/AIDS-related articles, respectively. Summaries of the top-ranked articles in both categories are presented.
  
  
  CONCLUSIONS
  Major topics explored in the top-ranked ID articles of 2013 include the use of cefepime for gram-negative infections due to AmpC or extended-spectrum β-lactamase-producing Enterobacteriaceae, optimizing antibiotic therapy through the use of extended- or continuous-infusion regimens, the use of the oral integrase inhibitor dolutegravir to combat HIV disease, and new approaches to treatment of Clostridium difficile infection and enterococcal endocarditis.
authors.affiliation: Andrew S. Hunter, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX. David J. Guervil, Pharm.D., is Clinical Pharmacy Specialist-Infectious Diseases, Memorial Hermann-Texas Medical Center, Houston. Katherine K. Perez, Pharm. D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases, Houston Methodist Hospital and Houston Methodist Research Institute, Houston. Amy N. Schilling, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases/Internal Medicine, Memorial Hermann-The Woodlands Hospital, The Woodlands, TX. Collin N. Verheyden, Pharm.D., BCPS, is Postgraduate Year 2 (PGY2) Infectious Diseases Pharmacy Resident, Michael E. DeBakey Veterans Affairs Medical Center. Nancy N. Vuong, Pharm.D., BCPS, is PGY2 Infectious Diseases Pharmacotherapy Resident, Cardinal Health and University of Houston College of Pharmacy, Houston. Ran Xu, Ph.D., Pharm.D., BCPS, is Clinical Pharmacy Manager, St. Luke's The Woodlands Hospital, The Woodlands.
authors.forename: Andrew S
authors.initials: AS
authors.lastname: Hunter
authors.affiliation: Andrew S. Hunter, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX. David J. Guervil, Pharm.D., is Clinical Pharmacy Specialist-Infectious Diseases, Memorial Hermann-Texas Medical Center, Houston. Katherine K. Perez, Pharm. D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases, Houston Methodist Hospital and Houston Methodist Research Institute, Houston. Amy N. Schilling, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases/Internal Medicine, Memorial Hermann-The Woodlands Hospital, The Woodlands, TX. Collin N. Verheyden, Pharm.D., BCPS, is Postgraduate Year 2 (PGY2) Infectious Diseases Pharmacy Resident, Michael E. DeBakey Veterans Affairs Medical Center. Nancy N. Vuong, Pharm.D., BCPS, is PGY2 Infectious Diseases Pharmacotherapy Resident, Cardinal Health and University of Houston College of Pharmacy, Houston. Ran Xu, Ph.D., Pharm.D., BCPS, is Clinical Pharmacy Manager, St. Luke's The Woodlands Hospital, The Woodlands. david.guervil@memorialhermann.org.
authors.forename: David J
authors.initials: DJ
authors.lastname: Guervil
authors.affiliation: Andrew S. Hunter, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX. David J. Guervil, Pharm.D., is Clinical Pharmacy Specialist-Infectious Diseases, Memorial Hermann-Texas Medical Center, Houston. Katherine K. Perez, Pharm. D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases, Houston Methodist Hospital and Houston Methodist Research Institute, Houston. Amy N. Schilling, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases/Internal Medicine, Memorial Hermann-The Woodlands Hospital, The Woodlands, TX. Collin N. Verheyden, Pharm.D., BCPS, is Postgraduate Year 2 (PGY2) Infectious Diseases Pharmacy Resident, Michael E. DeBakey Veterans Affairs Medical Center. Nancy N. Vuong, Pharm.D., BCPS, is PGY2 Infectious Diseases Pharmacotherapy Resident, Cardinal Health and University of Houston College of Pharmacy, Houston. Ran Xu, Ph.D., Pharm.D., BCPS, is Clinical Pharmacy Manager, St. Luke's The Woodlands Hospital, The Woodlands.
authors.forename: Katherine K
authors.initials: KK
authors.lastname: Perez
authors.affiliation: Andrew S. Hunter, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX. David J. Guervil, Pharm.D., is Clinical Pharmacy Specialist-Infectious Diseases, Memorial Hermann-Texas Medical Center, Houston. Katherine K. Perez, Pharm. D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases, Houston Methodist Hospital and Houston Methodist Research Institute, Houston. Amy N. Schilling, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases/Internal Medicine, Memorial Hermann-The Woodlands Hospital, The Woodlands, TX. Collin N. Verheyden, Pharm.D., BCPS, is Postgraduate Year 2 (PGY2) Infectious Diseases Pharmacy Resident, Michael E. DeBakey Veterans Affairs Medical Center. Nancy N. Vuong, Pharm.D., BCPS, is PGY2 Infectious Diseases Pharmacotherapy Resident, Cardinal Health and University of Houston College of Pharmacy, Houston. Ran Xu, Ph.D., Pharm.D., BCPS, is Clinical Pharmacy Manager, St. Luke's The Woodlands Hospital, The Woodlands.
authors.forename: Amy N
authors.initials: AN
authors.lastname: Schilling
authors.affiliation: Andrew S. Hunter, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX. David J. Guervil, Pharm.D., is Clinical Pharmacy Specialist-Infectious Diseases, Memorial Hermann-Texas Medical Center, Houston. Katherine K. Perez, Pharm. D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases, Houston Methodist Hospital and Houston Methodist Research Institute, Houston. Amy N. Schilling, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases/Internal Medicine, Memorial Hermann-The Woodlands Hospital, The Woodlands, TX. Collin N. Verheyden, Pharm.D., BCPS, is Postgraduate Year 2 (PGY2) Infectious Diseases Pharmacy Resident, Michael E. DeBakey Veterans Affairs Medical Center. Nancy N. Vuong, Pharm.D., BCPS, is PGY2 Infectious Diseases Pharmacotherapy Resident, Cardinal Health and University of Houston College of Pharmacy, Houston. Ran Xu, Ph.D., Pharm.D., BCPS, is Clinical Pharmacy Manager, St. Luke's The Woodlands Hospital, The Woodlands.
authors.forename: Collin N
authors.initials: CN
authors.lastname: Verheyden
authors.affiliation: Andrew S. Hunter, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX. David J. Guervil, Pharm.D., is Clinical Pharmacy Specialist-Infectious Diseases, Memorial Hermann-Texas Medical Center, Houston. Katherine K. Perez, Pharm. D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases, Houston Methodist Hospital and Houston Methodist Research Institute, Houston. Amy N. Schilling, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases/Internal Medicine, Memorial Hermann-The Woodlands Hospital, The Woodlands, TX. Collin N. Verheyden, Pharm.D., BCPS, is Postgraduate Year 2 (PGY2) Infectious Diseases Pharmacy Resident, Michael E. DeBakey Veterans Affairs Medical Center. Nancy N. Vuong, Pharm.D., BCPS, is PGY2 Infectious Diseases Pharmacotherapy Resident, Cardinal Health and University of Houston College of Pharmacy, Houston. Ran Xu, Ph.D., Pharm.D., BCPS, is Clinical Pharmacy Manager, St. Luke's The Woodlands Hospital, The Woodlands.
authors.forename: Nancy N
authors.initials: NN
authors.lastname: Vuong
authors.affiliation: Andrew S. Hunter, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX. David J. Guervil, Pharm.D., is Clinical Pharmacy Specialist-Infectious Diseases, Memorial Hermann-Texas Medical Center, Houston. Katherine K. Perez, Pharm. D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases, Houston Methodist Hospital and Houston Methodist Research Institute, Houston. Amy N. Schilling, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Infectious Diseases/Internal Medicine, Memorial Hermann-The Woodlands Hospital, The Woodlands, TX. Collin N. Verheyden, Pharm.D., BCPS, is Postgraduate Year 2 (PGY2) Infectious Diseases Pharmacy Resident, Michael E. DeBakey Veterans Affairs Medical Center. Nancy N. Vuong, Pharm.D., BCPS, is PGY2 Infectious Diseases Pharmacotherapy Resident, Cardinal Health and University of Houston College of Pharmacy, Houston. Ran Xu, Ph.D., Pharm.D., BCPS, is Clinical Pharmacy Manager, St. Luke's The Woodlands Hospital, The Woodlands.
authors.forename: Ran
authors.initials: R
authors.lastname: Xu
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D003141:Communicable Diseases / Q000188:drug therapy* / Q000382:microbiology; D015658:HIV Infections / Q000188:drug therapy; D006801:Humans; D010380:Peer Review; D010506:Periodicals as Topic / Q000706:statistics & numerical data*
chemical_list: D000890:Anti-Infective Agents