title: Whole-genome sequencing of Burkholderia pseudomallei isolates from an unusual melioidosis case identifies a polyclonal infection with the same multilocus sequence type.
abstract: Twelve Burkholderia pseudomallei isolates collected over a 32-month period from a patient with chronic melioidosis demonstrated identical multilocus sequence types (STs). However, whole-genome sequencing suggests a polyclonal infection. This study is the first to report a mixed infection with the same ST.
authors.affiliation: Global and Tropical Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, USA erin.price@menzies.edu.au.
authors.forename: Erin P
authors.identifier: http://orcid.org/0000-0002-1079-4882
authors.initials: EP
authors.lastname: Price
authors.affiliation: Global and Tropical Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, USA.
authors.forename: Derek S
authors.initials: DS
authors.lastname: Sarovich
authors.affiliation: Global and Tropical Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia.
authors.forename: Linda
authors.initials: L
authors.lastname: Viberg
authors.affiliation: Global and Tropical Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia.
authors.forename: Mark
authors.initials: M
authors.lastname: Mayo
authors.affiliation: Global and Tropical Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia.
authors.forename: Mirjam
authors.initials: M
authors.lastname: Kaestli
authors.affiliation: Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, USA.
authors.forename: Apichai
authors.initials: A
authors.lastname: Tuanyok
authors.affiliation: Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, USA.
authors.forename: Jeffrey T
authors.initials: JT
authors.lastname: Foster
authors.affiliation: Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, USA.
authors.forename: Paul
authors.initials: P
authors.lastname: Keim
authors.affiliation: Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, USA.
authors.forename: Talima
authors.initials: T
authors.lastname: Pearson
authors.affiliation: Global and Tropical Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia Department of Infectious Diseases and Northern Territory Medical Program, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
authors.forename: Bart J
authors.initials: BJ
authors.lastname: Currie
mesh_terms: D015373:Bacterial Typing Techniques / Q000379:methods*; D016957:Burkholderia pseudomallei / Q000145:classification* / Q000235:genetics*; D016680:Genome, Bacterial / Q000235:genetics*; D006801:Humans; D008297:Male; D008554:Melioidosis / Q000382:microbiology*; D008875:Middle Aged; D058885:Multilocus Sequence Typing / Q000379:methods*; D010802:Phylogeny