title: RADAI-5 to monitor rheumatoid arthritis.
abstract: Providing the physician with sufficient information about the disease course can be regarded as the most important requirement for any disease assessment tool besides easy applicability and time-sparing documentation. Applying the RADAI-5 in daily routine provides the patient's view at any time completing the questionnaire. In a first study, the RADAI-5 resulted to be highly significantly correlated to the RADAI, and all composite indexes. Changes of the RADAI-5, the DAS28-ESR, and the CDAI were significantly correlated, indicating the instrument's sensitivity to change. A second study including 392 RA patients led to the establishment of thresholds for disease activity categories according to the RADAI-5, as follows: 0.0 up to 1.4 for a remission-like state, 1.6 up to 3.0 for mild disease activity, 3.2 up to 5.4 for moderate and from 5.6 up to 10.0 for high disease activity. In a third study, remission according to the RADAI-5 appeared to be highly specific for the ACR/EULAR criteria for remission The RADAI-5 questionnaire constitutes an easily applicable tool for routine RA monitoring, providing physicians with reliable information about the disease course and sensitivity enough to sound the alarm should complications occur.
authors.affiliation: 2nd Dept. of Medicine, Center for Rheumatology Lower Austria, Karl Landsteiner Institute for Clinical Rheumatology, State Hospital Stockerau, Stockerau, Austria. burkhard.leeb@stockerau.lknoe.at.
authors.forename: B F
authors.initials: BF
authors.lastname: Leeb
authors.forename: P M
authors.initials: PM
authors.lastname: Haindl
authors.forename: H P
authors.initials: HP
authors.lastname: Brezinschek
authors.forename: T
authors.initials: T
authors.lastname: Nothnagl
authors.forename: B
authors.initials: B
authors.lastname: Rintelen
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D001799:Blood Sedimentation; D018450:Disease Progression; D006304:Health Status; D006305:Health Status Indicators; D006801:Humans; D007596:Joints / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology; D011237:Predictive Value of Tests; D012074:Remission Induction; D012219:Rheumatology / Q000379:methods*; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D018501:Antirheumatic Agents