title: Probing structural changes of self assembled i-motif DNA.
abstract: We report an i-motif structural probing system based on Thioflavin T (ThT) as a fluorescent sensor. This probe can discriminate the structural changes of RET and Rb i-motif sequences according to pH change.
authors.affiliation: Controlled Release and Delivery Lab (CRD), Advanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), Thuwal, Makkah 23955-6900, Kingdom of Saudi Arabia. niveen.khashab@kaust.edu.sa.
authors.forename: Il Joon
authors.initials: IJ
authors.lastname: Lee
authors.forename: Sachin P
authors.initials: SP
authors.lastname: Patil
authors.forename: Karim
authors.initials: K
authors.lastname: Fhayli
authors.forename: Shahad
authors.initials: S
authors.lastname: Alsaiari
authors.forename: Niveen M
authors.initials: NM
authors.lastname: Khashab
mesh_terms: D052160:Benzothiazoles; D015374:Biosensing Techniques; D002942:Circular Dichroism; D005456:Fluorescent Dyes / Q000032:analysis*; D006863:Hydrogen-Ion Concentration; D059372:Nucleotide Motifs; D051096:Proto-Oncogene Proteins c-ret / Q000235:genetics*; D016160:Retinoblastoma Protein / Q000235:genetics*; D013050:Spectrometry, Fluorescence; D013844:Thiazoles / Q000032:analysis*
chemical_list: D052160:Benzothiazoles; D005456:Fluorescent Dyes; D016160:Retinoblastoma Protein; D013844:Thiazoles; C009462:thioflavin T; D051096:Proto-Oncogene Proteins c-ret