title: A simple, versatile valve model for use in lumped parameter and one-dimensional cardiovascular models.
abstract: Lumped parameter and one-dimensional models of the cardiovascular system generally employ ideal cardiac and/or venous valves that open and close instantaneously. However, under normal or pathological conditions, valves can exhibit complex motions that are mainly determined by the instantaneous difference between upstream and downstream pressures. We present a simple valve model that predicts valve motion on the basis of this pressure difference, and can be used to investigate not only valve pathology, but a wide range of cardiac and vascular factors that are likely to influence valve motion.
authors.affiliation: Heart Research Group, Murdoch Childrens Research Institute, Flemington Rd. Parkville, VIC, Australia; Department of Paediatrics, University of Melbourne, Parkville, VIC, Australia. jonathan.mynard@mcri.edu.au.
authors.forename: J P
authors.initials: JP
authors.lastname: Mynard
authors.forename: M R
authors.initials: MR
authors.lastname: Davidson
authors.forename: D J
authors.initials: DJ
authors.lastname: Penny
authors.forename: J J
authors.initials: JJ
authors.lastname: Smolich
mesh_terms: D001021:Aortic Valve / Q000502:physiology*; D006801:Humans; D008955:Models, Cardiovascular
keywords: aortic valve; mitral valve; pulmonary hypertension; pulmonary valve; regurgitation; stenosis; tricuspid valve; venous valve