title: An in Vitro Experimental Study on the Antimicrobial Activity of Silicone Oil against Anaerobic Bacteria.
abstract: OBJECTIVE
  To investigate the in vitro antimicrobial activity of silicone oil against anaerobic agents, specifically Propionibacterium acnes, Peptostreptococcus spp., Peptostreptococcus anaerobius, Bacteroides fragilis, Fuobacterium spp., and Clostridium tertium.
  
  
  METHODS
  A 0.5 McFarland turbidity of Propionibacterium acnes, Peptostreptococcus spp., Peptostreptococcus anaerobius, Bacteroides fragilis, Fuobacterium spp., and Clostridium tertium was prepared, and 0.1 mL was inoculated into 0.9 mL of silicone oil. Control inoculations were performed in anaerobic blood agar and fluid thioglycollate medium without silicone oil.
  
  
  RESULTS
  Propionibacterium acnes retained their viability on the 3rd day in the presence of silicone oil. In total, 9.7 × 10(6) colonies were enumerated from 1 mL of silicone oil. After a prolonged incubation of 7 days, the number of colonies observed was 9.2 × 10(6). The other bacteria disappeared after the 3rd day of incubation in silicone oil.
  
  
  CONCLUSIONS
  Propionibacterium acnes, which is the most common chronic postoperative endophthalmitis agent, is thought to be resistant to silicone oil.
authors.affiliation: a Cerrahpasa Medical Faculty, Department of Ophthalmology .
authors.forename: Ceyhun
authors.initials: C
authors.lastname: Arici
authors.affiliation: a Cerrahpasa Medical Faculty, Department of Ophthalmology .
authors.forename: Cengiz
authors.initials: C
authors.lastname: Aras
authors.affiliation: b Cerrahpasa Medical Faculty, Department of Medical Microbiology , Istanbul University , Istanbul , Turkey .
authors.forename: Hrisi Bahar
authors.initials: HB
authors.lastname: Tokman
authors.affiliation: c Medical Faculty, Department of Medical Microbiology , Bahcesehir University , Istanbul , Turkey.
authors.forename: Muzeyyen Mamal
authors.initials: MM
authors.lastname: Torun
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D001421:Bacteria, Anaerobic / Q000187:drug effects* / Q000302:isolation & purification; D001431:Bacteriological Techniques; D015169:Colony Count, Microbial; D024881:Drug Resistance, Bacterial; D008826:Microbial Sensitivity Tests; D012827:Silicone Oils / Q000494:pharmacology*
chemical_list: D000890:Anti-Infective Agents; D012827:Silicone Oils
keywords: Anaerobic bacteria; antimicrobial resistance; antimicrobial susceptibility; endophthalmitis; silicone oil