title: Tuning the selectivity of triplex DNA receptors.
abstract: Effects of hydrogen bonding clamps on the selectivity of triplex DNA receptors were studied. Incorporation of a 5-methyl-2-thiocytosine base to the parallel homopyrimidine region of a triplex receptor enabled selective molecular recognition of an inosine ligand.
authors.affiliation: Department of Chemistry and Environmental Science, New Jersey Institute of Technology, Newark, NJ 07102, USA. haidong.huang@njit.edu.
authors.forename: Haidong
authors.initials: H
authors.lastname: Huang
authors.forename: Peter C
authors.initials: PC
authors.lastname: Tlatelpa
mesh_terms: D003596:Cytosine / Q000031:analogs & derivatives / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D006860:Hydrogen Bonding; D007288:Inosine / Q000737:chemistry*; D008024:Ligands; D008958:Models, Molecular; D008968:Molecular Conformation; D011743:Pyrimidines / Q000737:chemistry; D011956:Receptors, Cell Surface / Q000737:chemistry*
chemical_list: C033365:DNA receptor; D008024:Ligands; D011743:Pyrimidines; D011956:Receptors, Cell Surface; C051802:triplex DNA; C058511:2-thiocytosine; D007288:Inosine; D003596:Cytosine; D004247:DNA; C030986:pyrimidine