title: Menopausal hormone treatment in postmenopausal women: risks and benefits.
abstract: Our objectives in this review were to examine the relevant menopausal hormone treatment (MHT) trials in postmenopausal women during the past 3 decades, provide an insight analysis of these studies from a clinical point of view, determine the efficacy and applicability of hormone therapy in the prevention of cardiovascular diseases, and provide suggestions on the use of MHT as a cardiovascular disease prophylaxis based on the available data. MHT may have a more complicated role in cardiovascular protection, and there is a need for further research to elucidate the dose and type of estrogen, its route of administration, the time of MHT initiation, and the preventive role of MHT in women's health.
authors.affiliation: From the Richmond University Medical Center, Department of Medicine, Cardiology and Endocrinology, Staten Island, NY.
authors.forename: George V
authors.initials: GV
authors.lastname: Dous
authors.affiliation: From the Richmond University Medical Center, Department of Medicine, Cardiology and Endocrinology, Staten Island, NY.
authors.forename: Richard
authors.initials: R
authors.lastname: Grodman
authors.affiliation: From the Richmond University Medical Center, Department of Medicine, Cardiology and Endocrinology, Staten Island, NY.
authors.forename: Adenieki
authors.initials: A
authors.lastname: Mornan
authors.affiliation: From the Richmond University Medical Center, Department of Medicine, Cardiology and Endocrinology, Staten Island, NY.
authors.forename: Philip
authors.initials: P
authors.lastname: Otterbeck
authors.affiliation: From the Richmond University Medical Center, Department of Medicine, Cardiology and Endocrinology, Staten Island, NY.
authors.forename: Angela
authors.initials: A
authors.lastname: Grigos
mesh_terms: D000818:Animals; D002318:Cardiovascular Diseases / Q000517:prevention & control*; D003324:Coronary Artery Disease / Q000517:prevention & control; D018450:Disease Progression; D015914:Estrogen Replacement Therapy; D004967:Estrogens / Q000502:physiology; D005260:Female; D006801:Humans; D018570:Risk Assessment; D014280:Triglycerides / Q000097:blood
chemical_list: D004967:Estrogens; D014280:Triglycerides