title: Splenial and white matter lesions showing transiently-reduced diffusion in mild encephalopathy monitored with MR spectroscopy and imaging.
abstract: We report the time course of magnetic resonance imaging and spectroscopy of a case with lesions of the splenium and white matter with transiently reduced diffusion in clinically reversible encephalopathy. Initially normal spectroscopy showed slightly elevated choline. Signal abnormality in T2-weighted and fluid-attenuated inversion recovery images persisted for 90 days. Lesions of the splenium and white matter with transiently reduced diffusion in clinically reversible encephalopathy are not always reversible and may reflect heightened glial cell-membrane turnover without neuronal damage.
authors.affiliation: Department of Radiology, Kanazawa University Hospital.
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Ueda
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Yoshie
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Aburano
authors.forename: Masahiro
authors.initials: M
authors.lastname: Hashimoto
authors.forename: Osamu
authors.initials: O
authors.lastname: Matsui
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Gabata
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001927:Brain Diseases / Q000473:pathology* / Q000628:therapy; D003337:Corpus Callosum / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D005440:Fluid Therapy; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D066127:White Matter / Q000473:pathology*; D055815:Young Adult
chemical_list: D000305:Adrenal Cortex Hormones