title: [The method of analysis of distribution of erythrocytes by density: practical guidelines].
abstract: The article describes the phthalate method of analysis of distribution of erythrocytes by density and demonstrates its possibility. The distribution of erythrocytes by density is implemented using centrifugation of blood in micro-hematocrit capillaries in presence of compounds of dimethyl- and dibuthylphthalates of known density. The acquisition of such clinically reliable parameters of distribution of erythrocytes by density as mean density of erythrocytes, width of distribution of erythrocytes by density, light and heavy fraction of erythrocytes and maximum of curve of distribution of erythrocytes by density is described. The causes of deviation of distribution of erythrocytes by density from standard values under various pathological conditions are considered. The syndrome of dehydration of erythrocytes is described in details. The simple and accessible method of acquisition of distribution of erythrocytes by density is described. It is demonstrated that analysis of distribution of erythrocytes by density makes it possible to determine character of changes occurring with erythrocytes. The monitoring of parameters of distribution of erythrocytes by density allows evaluating dynamics of pathological process and effectiveness of therapy.
authors.forename: E S
authors.initials: ES
authors.lastname: Shukrina
authors.forename: V M
authors.initials: VM
authors.lastname: Nesterenko
authors.forename: N V
authors.initials: NV
authors.lastname: Tsvetaeva
authors.forename: O F
authors.initials: OF
authors.lastname: Nikulina
authors.forename: F I
authors.initials: FI
authors.lastname: Ataullakhanov
mesh_terms: D001799:Blood Sedimentation; D002499:Centrifugation, Density Gradient / Q000379:methods; D004912:Erythrocytes / Q000737:chemistry* / Q000166:cytology*; D005260:Female; D006400:Hematocrit / Q000379:methods; D006801:Humans; D008297:Male; D017410:Practice Guidelines as Topic