title: Comparison of perioperative complications and hospitalization outcomes after ankle arthrodesis versus total ankle arthroplasty from 2002 to 2011.
abstract: BACKGROUND
  The aim of this study was to analyze a validated, nationally representative admissions database in order to compare perioperative complications and hospitalization outcomes associated with ankle arthrodesis (AAD) versus ankle arthroplasty (TAA).
  
  
  METHODS
  Using the Nationwide Inpatient Sample (NIS) database from 2002 to 2011, 12 250 patients who underwent AAD and 3002 patients who underwent TAA were identified based on International Classification of Diseases, Ninth Revision (ICD-9) codes. The demographics, comorbidities, and perioperative outcomes during the index hospital stay were compared between patients who underwent AAD and TAA. Multivariate analysis was performed to adjust for differences in demographics and comorbidities between the 2 groups.
  
  
  RESULTS
  Multivariate analysis demonstrated that TAA was independently associated with a decreased risk of blood transfusion (relative risk [RR] = 0.53, P < .001), non-home discharge (RR = 0.70, P < .001), and overall complication (RR = 0.79, P = .03). There were similar rates of pneumonia, deep vein thrombosis, pulmonary embolus, cerebrovascular accident, myocardial infarction, and mortality. TAA was independently associated with a significantly higher hospital charge (difference = $24 431, P < .001). There was no significant difference in the adjusted length of stay between the 2 groups (P = .13).
  
  
  CONCLUSIONS
  TAA was independently associated with a lower risk of blood transfusion, non-home discharge, and overall complication when compared to AAD during the index hospitalization period. TAA was also independently associated with a higher hospitalization charge, but length of stay was similar between the 2 groups. Until long-term comparative studies are performed, the optimal treatment for end-stage ankle arthritis remains controversial, this study provides greater clarity with regard to hospitalization outcomes after the 2 procedures and shows no significant difference in risk for the majority of medical perioperative complications.
  
  
  METHODS
  Level III, comparative series.
authors.affiliation: University of Chicago Medical Center, Chicago, IL, USA.
authors.forename: Jimmy J
authors.initials: JJ
authors.lastname: Jiang
authors.affiliation: University of Chicago Medical Center, Chicago, IL, USA o.schipper@gmail.com.
authors.forename: Oliver N
authors.initials: ON
authors.lastname: Schipper
authors.affiliation: University of Chicago Medical Center, Chicago, IL, USA.
authors.forename: Noelle
authors.initials: N
authors.lastname: Whyte
authors.affiliation: NorthShore University HealthSystem, Evanston, IL, USA.
authors.forename: Jason L
authors.initials: JL
authors.lastname: Koh
authors.affiliation: University of Chicago Medical Center, Chicago, IL, USA.
authors.forename: Brian C
authors.initials: BC
authors.lastname: Toolan
mesh_terms: D017677:Age Distribution; D000368:Aged; D000843:Ankle Joint / Q000503:physiopathology / Q000601:surgery*; D001174:Arthrodesis / Q000009:adverse effects* / Q000379:methods; D058737:Arthroplasty, Replacement, Ankle / Q000009:adverse effects* / Q000379:methods; D016009:Chi-Square Distribution; D015331:Cohort Studies; D016208:Databases, Factual; D005260:Female; D005500:Follow-Up Studies; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010003:Osteoarthritis / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D059035:Perioperative Period; D011183:Postoperative Complications / Q000175:diagnosis / Q000453:epidemiology*; D011859:Radiography; D020127:Recovery of Function; D012189:Retrospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D017678:Sex Distribution; D016896:Treatment Outcome
keywords: ankle arthritis; ankle arthrodesis; ankle arthroplasty; hospitalization outcomes; perioperative complications; tibiotalar fusion