title: Squamous-cell carcinoma of the tongue following therapy of rheumatoid arthritis with abatacept.
abstract: A patient affected by rheumatoid arthritis developed a squamous-cell carcinoma probably due to abatacept, according to Naranjo algorithm. The case describes this adverse reaction for the first time and highlights the need for additional studies to establish the long-term risk profile of abatacept.
authors.affiliation: Sardinian Regional Center of Pharmacovigilance, Unit of Clinical Pharmacology, University Hospital of Cagliari (AOUCA) Cagliari, Italy.
authors.forename: Arianna
authors.initials: A
authors.lastname: Deidda
authors.affiliation: Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari Cagliari, Italy.
authors.forename: Claudia
authors.initials: C
authors.lastname: Pisanu
authors.affiliation: Regional Councillorship of Health, "Regione Autonoma della Sardegna" Cagliari, Italy.
authors.forename: Donatella
authors.initials: D
authors.lastname: Garau
authors.affiliation: Unit of Rheumatology, University Hospital of Sassari (AOUSS) Sassari, Italy.
authors.forename: Maria Giovanna
authors.initials: MG
authors.lastname: Longu
authors.affiliation: Pharmacy Service, University Hospital of Sassari (AOUSS) Sassari, Italy.
authors.forename: Mario Domenico Luigi
authors.initials: MD
authors.lastname: Moretti
authors.affiliation: Pharmacy Service, University Hospital of Sassari (AOUSS) Sassari, Italy.
authors.forename: Maria Elena
authors.initials: ME
authors.lastname: Sanna
authors.affiliation: Pharmacy Service, University Hospital of Sassari (AOUSS) Sassari, Italy.
authors.forename: Grazia Maria Rita
authors.initials: GM
authors.lastname: Moretti
authors.affiliation: Sardinian Regional Center of Pharmacovigilance, Unit of Clinical Pharmacology, University Hospital of Cagliari (AOUCA) Cagliari, Italy.
authors.forename: Maria Erminia
authors.initials: ME
authors.lastname: Stochino
keywords: Abatacept; adverse drug reaction; carcinoma; rheumatoid arthritis