title: Hybrid enzymatic and organic electrocatalytic cascade for the complete oxidation of glycerol.
abstract: We demonstrate the complete electrochemical oxidation of the biofuel glycerol to CO2 using a hybrid enzymatic and small-molecule catalytic system. Combining an enzyme, oxalate oxidase, and an organic oxidation catalyst, 4-amino-TEMPO, we are able to electrochemically oxidize glycerol at a carbon electrode, while collecting up to as many as 16 electrons per molecule of fuel. Additionally, we investigate the anomalous electrocatalytic properties that allow 4-amino-TEMPO to be active under the acidic conditions that are required for oxalate oxidase to function.
authors.affiliation: Department of Chemistry, University of Utah , 315 South 1400 East, Salt Lake City, Utah 84112, United States.
authors.forename: David P
authors.initials: DP
authors.lastname: Hickey
authors.forename: Matthew S
authors.initials: MS
authors.lastname: McCammant
authors.forename: Fabien
authors.initials: F
authors.lastname: Giroud
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Sigman
authors.forename: Shelley D
authors.initials: SD
authors.lastname: Minteer
mesh_terms: D055162:Biocatalysis; D001674:Bioelectric Energy Sources; D002244:Carbon / Q000737:chemistry; D003497:Cyclic N-Oxides / Q000737:chemistry*; D004563:Electrochemistry; D004566:Electrodes; D005990:Glycerol / Q000737:chemistry*; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000378:metabolism*
chemical_list: D003497:Cyclic N-Oxides; C015527:4-amino-TEMPO; D002244:Carbon; D010088:Oxidoreductases; C020598:oxalate oxidase; D005990:Glycerol