title: The international serious adverse events consortium.
abstract: The International Serious Adverse Events Consortium is generating novel insights into the genetics and biology of drug-induced serious adverse events, and thereby improving pharmaceutical product development and decision-making.
authors.affiliation: iSAEC, 8770 West Bryn Mawr Avenue, Suite 1300, Chicago, Illinois 60631, USA.
authors.forename: Arthur L
authors.initials: AL
authors.lastname: Holden
authors.affiliation: iSAEC and at the S.J. Quinney College of Law, and Department of Human Genetics, University of Utah, Salt Lake City, Utah 84112, USA.
authors.forename: Jorge L
authors.initials: JL
authors.lastname: Contreras
authors.affiliation: iSAEC Scientific Management Committee and at Pfizer, New London, Connecticut 06320, USA.
authors.forename: Sally
authors.initials: S
authors.lastname: John
authors.affiliation: iSAEC Scientific Management Committee and at GlaxoSmithKline, Research Triangle Park, North Carolina 27709-3398, USA.
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Nelson
mesh_terms: D003299:Cooperative Behavior; D003657:Decision Making; D015195:Drug Design; D055808:Drug Discovery / Q000379:methods*; D004345:Drug Industry / Q000379:methods*; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D007391:International Cooperation