title: ST elevation myocardial infarction: recent advances and updates.
abstract: ST elevation myocardial infarction (STEMI) remains a leading cause of morbidity, mortality and disability worldwide. Statistically, a trend towards improvements in morbidity and mortality has been consistent over the years, which is attributed primarily to the modification of risk factors, healthier lifestyles, treatment advances and better management of door-to-balloon times via STEMI systems. However, a major challenge in the coming years will be the baby boomers (born between the years 1946 and 1964) coming into old age. The first baby boomers turned 65 in year 2011. As the baby boomers age in the coming years, the incidence of coronary heart disease is likely to increase, and so there will be a greater need to have major advances in the management of coronary heart disease in order to deal with this additional incidence. The scope of this article is to review recent advances in the management of STEMI and to provide an updated overview.
authors.affiliation: Department of Cardiology, University of Cincinnati, Cincinnati, OH, USA.
authors.forename: Leila
authors.initials: L
authors.lastname: Ganjehei
authors.forename: Urmiya Mamoon
authors.initials: UM
authors.lastname: Rashid
authors.forename: Sara
authors.initials: S
authors.lastname: Payami
authors.forename: Andrew Kim
authors.initials: AK
authors.lastname: Saal
mesh_terms: D000368:Aged; D005260:Female; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy*; D015428:Myocardial Reperfusion Injury / Q000503:physiopathology / Q000628:therapy; D062645:Percutaneous Coronary Intervention / Q000379:methods; D011379:Prognosis; D033581:Stem Cell Transplantation; D015607:Stents
keywords: ST elevation myocardial infarction; intracoronary stents; microvascular obstruction; reperfusion; stem cell therapy