title: Heat-sensitive moxibustion attenuates the inflammation after focal cerebral ischemia/ reperfusion injury.
abstract: Heat-sensitive moxibustion has neuroprotective effects against focal cerebral ischemia/reperfusion injury, however its mechanism of action remains unclear. In this study, rat models of focal cerebral ischemia/reperfusion injury were treated with suspended moxibustion at acupoint Dazhui (DU14) for 35 minutes. Results showed that suspended moxibustion decreased infarct volume, reduced cortical myeloperoxidase activity, and suppressed serum levels of proinflammatory cytokines in rats with focal cerebral ischemia/reperfusion injury. Our experimental findings indicated that heat-sensitive moxibustion can attenuate inflammation and promote repair after focal cerebral ischemia/reperfusion injury.
authors.affiliation: Basal Medical College of Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, Jiangxi Province, China.
authors.forename: Aijiao
authors.initials: A
authors.lastname: Xiao
authors.affiliation: Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, Jiangxi Province, China.
authors.forename: Rixin
authors.initials: R
authors.lastname: Chen
authors.affiliation: Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, Jiangxi Province, China.
authors.forename: Mingfei
authors.initials: M
authors.lastname: Kang
authors.affiliation: Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, Jiangxi Province, China.
authors.forename: Shenghai
authors.initials: S
authors.lastname: Tan
keywords: cerebral ischemia/reperfusion injury; heat-sensitive moxibustion; infarct volume; interleukin; middle cerebral artery occlusion; myeloperoxidase; neural regeneration; proinflammatory cytokines; suspended moxibustion; traditional Chinese medicine; traditional suspended moxibustion