title: Short-term effects of intravitreal triamcinolone acetonide injection on ocular blood flow evaluated with color Doppler ultrasonography.
abstract: OBJECTIVE
  To evaluate the changes in ocular blood flow with color Doppler ultrasonography (CDU) after intravitreal triamcinolone acetonide (IVTA) injection.
  
  
  METHODS
  A total of 46 patients who underwent IVTA (4 mg/0.1 mL) injection for diabetic macular edema (DME) (n=22), central retinal vein occlusion (CRVO) (n=12) and choroidal neovascular membrane (CNVM) (n=12) were included in the study. Peak systolic velocity (PSV), end diastolic velocity (EDV) and resistivity index (RI) were measured from the ophthalmic artery (OA), the central retinal artery (CRA) and the posterior ciliary artery (PCA) of each patient with CDU before, at the end of the first week and at the end of the first month following IVTA injection.
  
  
  RESULTS
  In the DME group, PSV of OA at the first of the first month (mean±SD) (37.48±10.87 cm/s) increased compared to pre-injection value (31.39±10.84 cm/s) (P=0.048). There was a statistically significant decrease (P=0.049) in PSV of CRA at the end of the first month (7.97±2.67 cm/s) compared to the pre-injection (9.47±3.37 cm/s). There was not any statistically significant difference on the other parameters in the DME group. Also, there was not any statistically significant difference on the ocular blood flow values in the CRVO and CNVM groups.
  
  
  CONCLUSIONS
  We observed that 4 mg/0.1 mL IVTA increased PSV of OA and decreased PSV of CRA in DME patients and did not have any effect on ocular blood flow values of CRVO and CNVM patients.
authors.affiliation: Ulucanlar Eye Training and Research Hospital, Ankara 06240, Turkey.
authors.forename: Mustafa Alpaslan
authors.initials: MA
authors.lastname: Anayol
authors.affiliation: Department of Ophthalmology, Ataturk Training and Research Hospital, Ankara 06800, Turkey.
authors.forename: Yasin
authors.initials: Y
authors.lastname: Toklu
authors.affiliation: Department of Radiology, Kecioren Training and Research Hospital, Ankara 06280, Turkey.
authors.forename: Elif Asik
authors.initials: EA
authors.lastname: Kamberoglu
authors.affiliation: Department of Ophthalmology, Ataturk Training and Research Hospital, Ankara 06800, Turkey.
authors.forename: Sabri
authors.initials: S
authors.lastname: Raza
authors.affiliation: Department of Ophthalmology, Kayseri Training and Research Hospital, Kayseri 38010, Turkey.
authors.forename: Hasan Basri
authors.initials: HB
authors.lastname: Arifoglu
authors.affiliation: Department of Ophthalmology, Bolu Izzet Baysal State Hospital, Bolu 14030, Turkey.
authors.forename: Huseyin
authors.initials: H
authors.lastname: Simavli
authors.affiliation: Ulucanlar Eye Training and Research Hospital, Ankara 06240, Turkey.
authors.forename: Ayse Gul Kocak
authors.initials: AG
authors.lastname: Altintas
authors.affiliation: Department of Ophthalmology, Yildirim Beyazit University School of Medicine, Ankara 06800, Turkey.
authors.forename: Saban
authors.initials: S
authors.lastname: Simsek
keywords: central retinal vein occlusion; choroidal neovascular membrane; diabetic macular edema; intravitreal triamcinolone acetonide; ocular blood flow