title: Determinants of nerve conduction recovery after nerve injuries: Compression duration and nerve fiber types.
abstract: BACKGROUND
  The aims of this study were to determine the influences of: (1) timing of nerve decompression; and (2) nerve fiber types on the patterns of nerve conduction studies (NCS) after nerve injury.
  
  
  METHODS
  Nerve conduction studies (NCS) were performed on 3 models of nerve injury: (1) crush injury due to transient nerve compression (crush group); (2) chronic constriction injury (CCI), or permanent compression (CCI group); and (3) CCI with removal of ligatures, or delayed nerve decompression (De-CCI group).
  
  
  RESULTS
  There were distinct patterns of NCS recovery. The crush and De-CCI groups achieved similar motor nerve recovery, better than that of the CCI group. In contrast, recovery of sensory nerves was limited in the CCI and De-CCI groups and was lower than in the crush group.
  
  
  CONCLUSIONS
  Immediate relief of compression resulted in the best recovery of motor and sensory nerve conduction. In contrast, delayed decompression restored only motor nerve conduction.
authors.affiliation: Department of Anatomy, Faculty of Medicine, Chung Shan Medical University, Taichung, Taiwan.
authors.forename: To-Jung
authors.initials: TJ
authors.lastname: Tseng
authors.affiliation: Department of Anatomy, College of Medicine, Kaohsiung Medical University, 100 Shih-Chuan 1st Road, Kaohsiung, 80708, Taiwan.
authors.forename: Tin-Hsin
authors.initials: TH
authors.lastname: Hsiao
authors.affiliation: Department of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.
authors.forename: Sung-Tsang
authors.initials: ST
authors.lastname: Hsieh
authors.affiliation: Department of Anatomy, College of Medicine, Kaohsiung Medical University, 100 Shih-Chuan 1st Road, Kaohsiung, 80708, Taiwan.
authors.forename: Yu-Lin
authors.initials: YL
authors.lastname: Hsieh
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000818:Animals; D004195:Disease Models, Animal; D008297:Male; D009412:Nerve Fibers / Q000145:classification* / Q000502:physiology*; D009416:Nerve Regeneration / Q000502:physiology; D009431:Neural Conduction / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D011930:Reaction Time; D020426:Sciatic Neuropathy / Q000473:pathology* / Q000503:physiopathology*; D018709:Statistics, Nonparametric; D013997:Time Factors
keywords: chronic constriction injury; compound muscle action potential; crush injury; nerve decompression; sensory nerve action potential