title: [Sexual dysfunction associated with antidepressant agents].
abstract: Sexual dysfunction is a common adverse effect of antidepressant treatment and a main reason for non-compliance with treatment. Different antidepressant agents are associated with different degrees of dysfunction, which is thought to depend on the agent's pharmacological profile. Agents with serotonergic activity, such as selective serotonin reuptake inhibitors (SSRI) and venlafaxine, yield the highest rate of sexual dysfunction. Non-SSRI agents such as duloxetine, reboxetine and mirtazapine have fewer sexual side effects than SSRI and venlafaxine. Agomelatine and bupropion are similar to placebo.
authors.affiliation: Ved Vænget 3, 2. th., 2100 København Ø. tfb233@alumni.ku.dk.
authors.forename: Sara Johanna
authors.initials: SJ
authors.lastname: Bergh
authors.forename: Annamaria
authors.initials: A
authors.lastname: Giraldi
mesh_terms: D018687:Antidepressive Agents, Second-Generation / Q000009:adverse effects* / Q000493:pharmacokinetics; D001143:Arousal / Q000187:drug effects / Q000502:physiology; D003866:Depressive Disorder / Q000188:drug therapy; D005260:Female; D006801:Humans; D007989:Libido / Q000187:drug effects / Q000502:physiology; D008297:Male; D009948:Orgasm / Q000187:drug effects / Q000502:physiology; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects* / Q000493:pharmacokinetics; D012725:Sexual Behavior / Q000187:drug effects / Q000502:physiology; D012735:Sexual Dysfunction, Physiological / Q000139:chemically induced* / Q000503:physiopathology
chemical_list: D018687:Antidepressive Agents, Second-Generation; D017367:Selective Serotonin Reuptake Inhibitors