title: Psychiatric factors do not affect recurrence risk of hyperemesis gravidarum.
abstract: OBJECTIVE
  The aim of this study is to determine whether psychiatric symptoms affect recurrence risk of hyperemesis gravidarum (HG).
  
  
  METHODS
  The study sample included 108 women with HG treated with i.v. fluids in their first pregnancy. Women were divided into two groups based on recurrence of HG in their second pregnancy. Participants submitted medical records and completed a survey regarding pregnancy characteristics and psychiatric symptoms. The χ(2) -test and Student's t-test were performed to compare the two groups.
  
  
  RESULTS
  Eighty-four women (71%) had a recurrence of HG requiring i.v. fluid for dehydration, and were compared with 34 women (29%) who did not have a recurrence. There were no significant differences in obstetric history, although there was a trend toward greater time between first and second pregnancy in the recurrence group (P = 0.08). There were no differences in pre-existing psychiatric diagnoses including anxiety, depression, bipolar disorder, panic or eating disorders. Following the first HG pregnancy, participants in both groups were well matched for all post-traumatic stress symptoms.
  
  
  CONCLUSIONS
  This study is the first to analyze the relationship of psychiatric factors to risk of recurrence of HG. No factors were identified that increase the risk of recurrence including stress symptoms following a HG pregnancy. Psychological sequelae associated with HG are probably a result of the physical symptoms of prolonged severe nausea and vomiting, medication and/or hospitalization, and likely play no role in disease etiology.
authors.affiliation: Department of Statistics, University of California, Los Angeles, Los Angeles, California, USA.
authors.forename: Aromalyn
authors.initials: A
authors.lastname: Magtira
authors.forename: Frederic Paik
authors.initials: FP
authors.lastname: Schoenberg
authors.forename: Kimber
authors.initials: K
authors.lastname: MacGibbon
authors.forename: Khalil
authors.initials: K
authors.lastname: Tabsh
authors.forename: Marlena S
authors.initials: MS
authors.lastname: Fejzo
mesh_terms: D000328:Adult; D001007:Anxiety / Q000150:complications / Q000523:psychology*; D003863:Depression / Q000150:complications / Q000523:psychology*; D005260:Female; D006801:Humans; D006939:Hyperemesis Gravidarum / Q000150:complications / Q000523:psychology*; D001523:Mental Disorders / Q000150:complications / Q000523:psychology*; D011247:Pregnancy; D012008:Recurrence; D012307:Risk Factors; D055815:Young Adult
keywords: anxiety; depression; hyperemesis gravidarum; post-traumatic stress symptoms; psychiatric