title: Invasive candidiasis and candidaemia in neonates and children: update on current guidelines.
abstract: Invasive candidiasis (IC) and candidaemia are leading causes of infectious morbidity and mortality among immunocompromised paediatric patients and those admitted to intensive care units. Despite improvements in diagnosis, prevention and treatment, both mortality rates and the economic burden of disease still remain high. To address this issue, several international societies and organisations have proposed guidelines for the management of IC/candidaemia in both neonates and children. In this article, we review current recommendations of the Infectious Diseases Society of America, the European Conference on Infection in Leukaemia, the European Society of Clinical Microbiology and Infectious Diseases and the German Speaking Mycological Society/Paul-Ehrlich Society for Chemotherapy for the management and prevention of IC/candidaemia in children and neonates.
authors.affiliation: Hematology Oncology Unit, 2nd Pediatric Department, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece.
authors.forename: Athanasios
authors.initials: A
authors.lastname: Tragiannidis
authors.forename: Christos
authors.initials: C
authors.lastname: Tsoulas
authors.forename: Andreas H
authors.initials: AH
authors.lastname: Groll
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use*; D058387:Candidemia / Q000175:diagnosis / Q000188:drug therapy* / Q000517:prevention & control*; D058365:Candidiasis, Invasive / Q000175:diagnosis / Q000188:drug therapy* / Q000517:prevention & control*; D002648:Child; D019468:Disease Management; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007362:Intensive Care Units
chemical_list: D000935:Antifungal Agents
keywords: Guidelines; candidaemia; children; invasive candidiasis; neonates; prevention; treatment