title: Chiral ligands derived from monoterpenes: application in the synthesis of optically pure secondary alcohols via asymmetric catalysis.
abstract: The preparation of optically pure secondary alcohols in the presence of catalysts based on chiral ligands derived from monoterpenes, such as pinenes, limonenes and carenes, is reviewed. A wide variety of these ligands has been synthesized and used in several catalytic reactions, including hydrogen transfer, C-C bond formation via addition of organozinc compounds to aldehydes, hydrosilylation, and oxazaborolidine reduction, leading to high activities and enantioselectivities.
authors.affiliation: Laboratoire de Chimie Organique Appliquée, Université Abdelmalek Essaadi, Faculté des Sciences, BP 2121-93002 Tetouan (Morocco), Fax: (+212) 5-39-99-45-00.
authors.forename: Mohammed Samir Ibn
authors.initials: MS
authors.lastname: El Alami
authors.forename: Mohamed Amin
authors.initials: MA
authors.lastname: El Amrani
authors.forename: Francine
authors.initials: F
authors.lastname: Agbossou-Niedercorn
authors.forename: Isabelle
authors.initials: I
authors.lastname: Suisse
authors.forename: André
authors.initials: A
authors.lastname: Mortreux
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D008024:Ligands; D039821:Monoterpenes / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000438:Alcohols; D008024:Ligands; D039821:Monoterpenes
keywords: alcohols; asymmetric catalysis; chiral ligands; natural product synthesis; terpenes