title: LOX-1 unlocks human plasma cell potential.
abstract: Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is best known for promoting atherosclerosis. In this issue of Immunity, Joo et al. (2014) find that dendritic cells triggered through LOX-1 can directly support plasmablast production via the production of the cytokines APRIL and BAFF.
authors.affiliation: Immunology Division, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst NSW 2010, Australia; St Vincent's Clinical School, UNSW Australia, 390 Victoria Street, Darlinghurst NSW 2010, Australia. Electronic address: r.brink@garvan.org.au.
authors.forename: Robert
authors.initials: R
authors.lastname: Brink
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D003713:Dendritic Cells / Q000276:immunology*; D019267:Hemagglutinin Glycoproteins, Influenza Virus / Q000276:immunology*; D006801:Humans; D017578:Immunoglobulin Class Switching / Q000276:immunology*; D008297:Male; D051127:Scavenger Receptors, Class E / Q000276:immunology*
chemical_list: C543345:H1N1 virus hemagglutinin; D019267:Hemagglutinin Glycoproteins, Influenza Virus; C495137:OLR1 protein, human; D051127:Scavenger Receptors, Class E