title: Incidence and timing of serious arrhythmias after early revascularization in non ST-elevation myocardial infarction.
abstract: BACKGROUND
  In contrast to ST-elevation myocardial infarction (STEMI), in non-STEMI (NSTEMI) patients the need for continuous rhythm monitoring in a coronary care unit, respective incidence and timing of serious arrhythmias are poorly defined.
  
  
  METHODS
  We used a derivation-validation design and data from two independent prospective cohorts of consecutive haemodynamically stable NSTEMI patients to evaluate the incidence and timing of serious arrhythmias after successful early percutaneous revascularization. Serious arrhythmia was prospectively defined as any arrhythmia that requires immediate medical attention including persistent ventricular tachycardia (>30 s), ventricular fibrillation, asystole, and high degree atrioventricular (AV)-block requiring pacemaker insertion during hospitalization.
  
  
  RESULTS
  In the derivation cohort, among 228 NSTEMI patients who underwent successful early percutaneous revascularization, one patient (0.4%, 95% confidence interval 0.02-2.8%) had a serious arrhythmia which occurred 21 h after revascularization. In the validation cohort, among 293 NSTEMI patients who underwent successful early percutaneous revascularization, no patient (0%, 95% confidence interval 0-1.6%) had a serious arrhythmia after revascularization.
  
  
  CONCLUSIONS
  The incidence of serious arrhythmias in NSTEMI patients after successful early revascularization seems to be very low.
authors.affiliation: Department of Cardiology, University Hospital Basel, Switzerland Department of Intensive Care, University Hospital Basel, Switzerland.
authors.forename: Karin
authors.initials: K
authors.lastname: Wildi
authors.affiliation: Department of Cardiology, University Hospital Basel, Switzerland Department of Cardiology, Kantonsspital Luzern, Switzerland.
authors.forename: Florim
authors.initials: F
authors.lastname: Cuculi
authors.affiliation: Department of Cardiology, University Hospital Basel, Switzerland Department of Intensive Care, University Hospital Basel, Switzerland.
authors.forename: Raphael
authors.initials: R
authors.lastname: Twerenbold
authors.affiliation: Department of Cardiology, University Hospital Basel, Switzerland.
authors.forename: Tanja
authors.initials: T
authors.lastname: Marxer
authors.affiliation: Department of Cardiology, University Hospital Basel, Switzerland Servicio de Urgencias y Pneumologia, CIBERES ISC III, Hospital del Mar - Institut Municipal d'Investigació Mèdica, Barcelona, Spain.
authors.forename: Maria
authors.initials: M
authors.lastname: Rubini Gimenez
authors.affiliation: Department of Cardiology, University Hospital Basel, Switzerland.
authors.forename: Tobias
authors.initials: T
authors.lastname: Reichlin
authors.affiliation: Department of Cardiology, University Hospital Basel, Switzerland.
authors.forename: Philip
authors.initials: P
authors.lastname: Haaf
authors.affiliation: Department of Cardiology, University Hospital Basel, Switzerland.
authors.forename: Raphael
authors.initials: R
authors.lastname: Monsch
authors.affiliation: Department of Intensive Care, University Hospital Basel, Switzerland.
authors.forename: Stefan
authors.initials: S
authors.lastname: Marsch
authors.affiliation: Department of Intensive Care, University Hospital Basel, Switzerland.
authors.forename: Patrick
authors.initials: P
authors.lastname: Hunziker
authors.affiliation: Emergency Department, University Hospital Basel, Switzerland.
authors.forename: Roland
authors.initials: R
authors.lastname: Bingisser
authors.affiliation: Department of Cardiology, University Hospital Basel, Switzerland.
authors.forename: Stefan
authors.initials: S
authors.lastname: Osswald
authors.affiliation: Department of Cardiology, University Hospital Basel, Switzerland Department of Cardiology, Kantonsspital Luzern, Switzerland.
authors.forename: Paul
authors.initials: P
authors.lastname: Erne
authors.affiliation: Department of Cardiology, University Hospital Basel, Switzerland chmueller@uhbs.ch.
authors.forename: Christian
authors.initials: C
authors.lastname: Mueller
mesh_terms: D000368:Aged; D001145:Arrhythmias, Cardiac / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D000072658:Non-ST Elevated Myocardial Infarction / Q000601:surgery*; D062645:Percutaneous Coronary Intervention / Q000379:methods*; D011446:Prospective Studies
keywords: NSTEMI; coronary care unit; monitoring; serious arrhythmia; successful revascularization