title: Highly enantioselective ring-opening reactions of aziridines with indole and its application in the building of C3-halogenated pyrroloindolines.
abstract: A magnesium-catalyzed asymmetric ring-opening reaction of aziridine with indole has been realized by employing commercially available chiral ligands. Both of the enantiomers of the ring-opening product could be obtained with good yields and a high level of enantioselectivity. The corresponding ring-opening product could be further transformed to various types of enantioenriched C3 -halogenated-pyrroloindolines.
authors.affiliation: School of Life Sciences, Lanzhou University, Lanzhou, 730000 (P. R. China).
authors.forename: Dongxu
authors.initials: D
authors.lastname: Yang
authors.forename: Linqing
authors.initials: L
authors.lastname: Wang
authors.forename: Fengxia
authors.initials: F
authors.lastname: Han
authors.forename: Dan
authors.initials: D
authors.lastname: Li
authors.forename: Depeng
authors.initials: D
authors.lastname: Zhao
authors.forename: Yiming
authors.initials: Y
authors.lastname: Cao
authors.forename: Yunxia
authors.initials: Y
authors.lastname: Ma
authors.forename: Weidong
authors.initials: W
authors.lastname: Kong
authors.forename: Quantao
authors.initials: Q
authors.lastname: Sun
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
keywords: asymmetric synthesis; cyclization; magnesium; ring-opening reactions