title: Ten year outcomes of participants in the REACT (Randomised Evaluation of Assertive Community Treatment in North London) study.
abstract: BACKGROUND
  A previous randomised controlled trial that investigated Assertive Community Treatment (ACT) in the UK (the REACT Study) found no clinical advantage over usual care delivered by Community Mental Health Teams (CMHTs) at 18 and 36 month follow-ups. No studies have investigated long term clinical and social outcomes for patients receiving ACT.
  
  
  METHODS
  We investigated inpatient service use, social outcomes, service contact and adverse events for the 251 REACT study participants 10 years after randomisation through case note review. Data were analysed using regression models adjusted for original treatment group allocation and changes in treatment group.
  
  
  RESULTS
  We found no statistically significant differences in outcomes by original treatment group over the 10 years. Those whose care remained with ACT, or transferred to ACT or forensic services, had more inpatient days over the 10 years (coefficient 223, 95% CI 83 to 363, p = 0.002) than those whose care remained with the CMHTs or were discharged to primary care. Being subject to a Community Treatment Order was associated with a greater chance of being under ACT at 10 year follow-up (OR 6.39, 95% CI 2.98 to 13.70, p <0.001).
  
  
  CONCLUSIONS
  The ACT teams in this study showed no clinical advantage over usual care provided by CMHTs at 10 year follow-up. We also found that the ACT teams accrued patients from the original study sample who had more complex needs than those who remained with or transferred to the CMHTs or primary care during this period. Further well conducted trials are needed to identify the most cost-effective approaches to supporting successful community living and optimum long term outcomes for this group.
authors.affiliation: Division of Psychiatry, University College London (UCL), Charles Bell House, 67-73 Riding House Street, London W1W 7EJ, UK. h.killaspy@ucl.ac.uk.
authors.forename: Helen
authors.initials: H
authors.lastname: Killaspy
authors.forename: Laia
authors.initials: L
authors.lastname: Mas-Expósito
authors.forename: Louise
authors.initials: L
authors.lastname: Marston
authors.forename: Michael
authors.initials: M
authors.lastname: King
mesh_terms: D003156:Community Mental Health Services / Q000191:economics* / Q000706:statistics & numerical data; D003362:Cost-Benefit Analysis; D005500:Follow-Up Studies; D006801:Humans; D007297:Inpatients; D008131:London; D001523:Mental Disorders / Q000191:economics / Q000628:therapy*