title: MAFG mediates CIMP in BRAF-mutant colorectal cancer.
abstract: An MAFG-containing corepressor complex induces CIMP in BRAF(V600E)-positive colorectal cancer.
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000235:genetics / Q000378:metabolism; D015179:Colorectal Neoplasms / Q000235:genetics* / Q000378:metabolism; D018899:CpG Islands; D006801:Humans; D051259:MafG Transcription Factor / Q000378:metabolism*; D008745:Methylation; D000070957:MutL Protein Homolog 1; D009154:Mutation; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism; D048493:Proto-Oncogene Proteins B-raf / Q000235:genetics* / Q000378:metabolism; D012097:Repressor Proteins / Q000378:metabolism*
chemical_list: D048868:Adaptor Proteins, Signal Transducing; C103944:MAFG protein, human; C501486:MLH1 protein, human; D051259:MafG Transcription Factor; D009687:Nuclear Proteins; D012097:Repressor Proteins; C482119:BRAF protein, human; D048493:Proto-Oncogene Proteins B-raf; D000070957:MutL Protein Homolog 1