Purtscher-like retinopathy associated with primary hypereosinophilic syndrome.
OBJECTIVE
To describe a patient with undiagnosed primary hypereosinophilic syndrome (HES) who presented with Purtscher-like retinopathy and to review the literature.


METHODS
Observational case report.


METHODS
A 25-year-old man presented with a 1-week history of bilateral visual blur. Examination revealed multiple peripapillary cotton-wool spots and few intraretinal hemorrhages. Clinical history was obtained and fluorescein angiography, systemic evaluation, laboratory studies, and histopathologic analysis of a bone marrow biopsy specimen were performed.


RESULTS
The patient was diagnosed with primary HES. No previous description was found in the literature.


CONCLUSIONS
HES should be considered in the differential diagnosis of Purtscher retinopathy. This case supports the microembolic theory of Purtscher retinopathy.
From the *Retina Service, Wills Eye Institute, Jefferson Medical College, Philadelphia, Pennsylvania; and the †Hematology/Oncology Service, Lankenau Hospital, Wynnewood, Pennsylvania.
Omesh P
OP
Gupta
Eric
E
Zegere
Joseph I
JI
Maguire