The role of motor proteins in signal propagation.
The signaling and transport systems of eucaryotic cells are tightly interconnected: intracellular transport along microtubules and microfilaments is required to position signaling-pathway components, while signaling molecules control activity of motor proteins and their interaction with tracks and cargoes. Recent data, however, give evidence that active transport is engaged in signaling as a means of signal transduction. This review focuses on this specific aspect of the interaction of two systems.
Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia. protres@vega.protres.ru.
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Gyoeva
D005057:Eukaryotic Cells / Q000378:metabolism; D006801:Humans; D020409:Molecular Motor Proteins / Q000378:metabolism*; D015398:Signal Transduction
D020409:Molecular Motor Proteins