Bilateral central retinal vein occlusion in a young person with storm syndrome.
OBJECTIVE
To report the presence of previously undescribed retinal abnormalities in patients with Storm and other progeric syndromes.


METHODS
Review of the clinical and photographic records of a patient with Storm syndrome who developed bilateral central retinal vein occlusion.


RESULTS
A 43-year-old woman with a diagnosis of Storm (Werner-like) syndrome, a connective tissue disease characterized by premature aging, presented with bilateral nonsimultaneous central retinal vein occlusion. The patient was also observed to have bilateral peripheral retinal pigment epithelial alterations.


CONCLUSIONS
Retinal abnormalities can be observed in patients with premature aging syndromes. These abnormalities include the development of venous occlusive disease and peripheral retinal pigment epithelial alterations at a relatively young age and may be related to the underlying genetic mutation.
From the Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California.
Srinivas R
SR
Sadda
Pearse A
PA
Keane