Visual outcome and incidence of glaucoma in patients with microspherophakia.
BACKGROUND
A number of ocular complications have been reported in microspherophakia. The literature however is limited to small case reports and the incidence of these complications is largely unknown. Our study describes a series of patients who presented to our hospital from 1998 to 2008.


METHODS
Data on the clinical and surgical findings of patients presented to us from 1998 to 2008 with microspherophakia were retrieved from the medical records and the results analyzed.


RESULTS
Thirty-six eyes of 18 patients were reviewed. The mean age at presentation was 16±10 years. All patients had varying degrees of lenticular myopia with a mean of -11.07±5.03 D. Glaucoma developed in 16 eyes (44.4%). Half of them had high IOP at presentation. Despite medical and surgical management IOP remained high in five eyes at the last follow-up. Sixteen eyes (44.4%) required lensectomy for dislocated crystalline lens. Lensectomy did not have any impact on the intraocular pressures. Homocysteinuria was the most common systemic association noted.


CONCLUSIONS
Microspherophakia is associated with a high incidence of lenticular myopia, subluxation of the crystalline lens and glaucoma. Management of glaucoma is difficult with the IOP remaining high in spite of combined medical and surgical management.
Department of Pediatric Ophthalmology, Aravind Eye Hospital, Madurai, India.
R
R
Muralidhar
Department of Pediatric Ophthalmology, Aravind Eye Hospital, Madurai, India.
K
K
Ankush
Department of Pediatric Ophthalmology, Aravind Eye Hospital, Madurai, India.
P
P
Vijayalakshmi
Department of Pediatric Ophthalmology, Aravind Eye Hospital, Madurai, India.
V P
VP
George
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003316:Corneal Diseases / Q000150:complications* / Q000503:physiopathology; D004479:Ectopia Lentis / Q000150:complications* / Q000503:physiopathology; D018463:Filtering Surgery; D005901:Glaucoma / Q000150:complications / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery; D006712:Homocystinuria / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D015994:Incidence; D007429:Intraocular Pressure; D007498:Iris / Q000002:abnormalities* / Q000503:physiopathology; D007906:Lens Subluxation / Q000209:etiology / Q000601:surgery; D009216:Myopia / Q000209:etiology; D014065:Tonometry, Ocular; D014792:Visual Acuity / Q000502:physiology*; D055815:Young Adult