Bioinspired self-assembly of tyrosinase-modified silicatein and fluorescent core-shell silica spheres.
Inspired by the intermolecular cross-linking of mussel foot proteins and their adhesive properties, tyrosinase has been used to modify recombinant silicatein. DOPA/DOPAquinone-mediated cross-linking and interfacial interactions enhanced both self-assembly of silicatein building blocks and templating of core-shell silica spheres, resulting in fluorescent biomimetic silicatein-silica hybrid mesofibers.
Institute of Physiological Chemistry, Duesbergweg 6, University Medical Center, Johannes Gutenberg-University, Mainz, Germany. Biomaterials Department, National Research Centre, Dokki, Cairo, Egypt.
T A
TA
Elkhooly
W E G
WE
Müller
X
X
Wang
W
W
Tremel
S
S
Isbert
M
M
Wiens
D000818:Animals; D040761:Biomimetic Materials / Q000138:chemical synthesis*; D002403:Cathepsins / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D008422:Materials Testing; D014442:Monophenol Monooxygenase / Q000737:chemistry*; D058608:Nanopores / Q000648:ultrastructure; D054118:Nanospheres / Q000737:chemistry* / Q000648:ultrastructure; D011161:Porifera / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*
D005456:Fluorescent Dyes; C112571:silicatein alpha; D012822:Silicon Dioxide; D014442:Monophenol Monooxygenase; D002403:Cathepsins