Anterior segment retinoblastoma detectable on magnetic resonance imaging.
OBJECTIVE
To report a case of retinoblastoma infiltrating the iris and ciliary body detected on magnetic resonance imaging.


METHODS
A retrospective case report with clinical evaluation, diagnostic testing, enucleation, and pathologic description.


RESULTS
A 2-year-old boy presented with hyphema and was noted to have a fluffy whitish iris mass. Retinoblastoma with anterior chamber extension was suggested on magnetic resonance imaging. T2-weighted images demonstrated a hypointense mass with a superficial layer of focal marked hypointensity, consistent with hemorrhage or calcification. Enucleation was performed, and histopathology confirmed retinoblastoma infiltrating the iris and ciliary body. No further treatment was administered, and the patient remains free of associated disease at age 5 years.


CONCLUSIONS
Retinoblastoma can invade the iris and ciliary body stroma. The use of magnetic resonance imaging in evaluating cases of anterior segment masses can demonstrate findings suggestive of retinoblastoma.
From the *Retina Center, Minneapolis, Minnesota; †Maimonades Hospital, Brooklyn, New York; ‡Corinthian Diagnostic Radiology, New York, New York; §Department of Pathology, University of Illinois Medical Center at Chicago, Chicago, Illinois; Departments of ¶Biomedical Sciences, **Pathology, and ††Ophthalmology, Oakland University William Beaumont School of Medicine, Rochester, Michigan; and ‡‡Ophthalmic Oncology Service, Memorial Sloan-Kettering Cancer Center, New York, New York.
M Vaughn
MV
Emerson
Norman
N
Saffra
Les Saint
LS
Louis
Amy
A
Lin
Robert
R
Folberg
David H
DH
Abramson