Force steadiness during a co-contraction task can be improved with practice, but only by young adults and not by middle-aged or old adults.
What is the central question of this study? Does the capacity to modulate afferent input to spinal motor neurons during steady submaximal contractions change with advancing age? What is the main finding and its importance? After practising a co-contraction task involving lower leg muscles, young subjects improved force steadiness by reducing the amount of Ia presynaptic inhibition as indexed by D1 inhibition. Middle-aged and old adults both found the task challenging, and force steadiness even worsened for old adults after practising the co-contraction task. Despite similar muscle strength for young and middle-aged adults, the capacity to modulate a spinal reflex pathway was reduced in middle-aged adults. This study compared the changes in steadiness and the modulation of presynaptic inhibition of soleus Ia afferents in young, middle-aged and old adults before and after a single session of practising a task that involved concurrent contraction of dorsiflexor and plantarflexor muscles. The hypothesis was that young subjects would be able to improve steadiness with practice by modulating Ia afferent feedback as indicated by changes in a measure of presynaptic inhibition (D1 inhibition), but that middle-aged and older subjects would exhibit a lesser ability to augment steadiness. There were no differences in steadiness between groups during an initial co-contraction trial (P = 0.713). Maximal voluntary contraction force for the plantarflexors was not significantly different between young and middle-aged subjects (P > 0.05), but it was significantly less in old subjects (P < 0.05). The main finding of the study was that young adults were able to improve steadiness by ∼19% (P < 0.001) during a co-contraction task after 50 min of practice, whereas there was no change for the middle-aged adults, and old adults became less steady by ∼15% (P < 0.05). The improvement in steadiness by young adults was accompanied by a significant reduction in the amount of Ia presynaptic inhibition as indexed by D1 inhibition (P < 0.01). Conversely, neither of the other two groups exhibited any change in D1 inhibition after practising the co-contraction task. In contrast to young subjects, middle-aged and old adults found the co-contraction task challenging and were not able to improve steadiness after practising the low-force isometric contraction.
Department of Integrative Physiology, University of Colorado, Boulder, CO, 80309, USA.
Matthew R
MR
Holmes
Jeffrey R
JR
Gould
Ilana
I
Peña-González
Roger M
RM
Enoka
D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology; D005260:Female; D006801:Humans; D007866:Leg / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology; D009119:Muscle Contraction / Q000502:physiology*; D053580:Muscle Strength / Q000502:physiology*; D018482:Muscle, Skeletal / Q000502:physiology*; D009475:Neurons, Afferent / Q000502:physiology; D012018:Reflex / Q000502:physiology; D013116:Spinal Cord / Q000502:physiology; D055815:Young Adult