The safety of fish oils for those whose risk of injury is high.
A diet rich in omega-3 polyunsaturated fatty acids (PUFAs) may decrease risk of cardiovascular disease by improving the blood lipid profile. The purpose of this review was to (1) determine if fish oil (omega-3) consumption increased the risk of hemorrhaging after a military injury and (2) whether an improvement in the omega-3 PUFA profile had an impact on survivability from military wounds. The authors found no evidence to contradict the existing U.S. Food and Drug Administration safety ruling that 3 g of omega-3 PUFA per day is generally regarded as safe. However, there is insufficient data with regard to the safety of consuming more than 3 g of omega-3 PUFA per day. More research is needed to safely recommend use of higher doses omega-3 PUFA.
Toyama Jonan Onsen Daini Hospital, Taromaru-nishimachi, Toyama City, Toyama 9398271, Japan.
Tomohito
T
Hamazaki
Elon University, Elon, NC, High Point University, High Point, NC.
Heather
H
Colleran
Department of Public Health, University of Toyama School of Medicine Toyama-city, Toyama 9300194, Japan.
Kei
K
Hamazaki
Department of Clinical Epidemiology, Translational Medical Center, National Center of Neurology and Psychiatry, Kodaira-city, Tokyo 187-8551, Japan.
Yutaka
Y
Matsuoka
Section of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, Toyama 930-0194, Japan.
Miho
M
Itomura
National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda MD 20892-9410.
Joseph
J
Hibbeln
D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage*; D005395:Fish Oils / Q000008:administration & dosage*; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D008889:Military Personnel; D012307:Risk Factors; D012449:Safety; D015996:Survival Rate; D014481:United States; D014857:Warfare; D014947:Wounds and Injuries / Q000150:complications*
D015525:Fatty Acids, Omega-3; D005395:Fish Oils