Cord blood full blood count parameters in Lagos, Nigeria.
BACKGROUND
Full blood count (FBC), one of the most frequently requested for laboratory investigations, is a simple, fast and cheap test and is a reliable indicator of health. Due to its usefulness in the assessment of health status of individuals, its parameters in cord blood, a major source of haemopoietic stem cell transplantation and an ideal source for laboratory investigations for newborns were determined to provide a useful guide to local neonatologists and stem cell transplant physicians.


METHODS
Three millilitres of umbilical cord blood was collected from 130 normal birth weight newborns (69 males and 61 females) whose cord were clamped immediately after delivery, at a teaching hospital in Lagos, Nigeria and full blood count parameters were determined using Sysmex autoanalyzer, model KX-21N. Consented mothers of the newborns were selected based on, age between 18 and 45 years; uneventful pregnancy and delivery and haemoglobin (Hb) concentration ≥ 10 g/dL.


RESULTS
There were no statistical gender differences in the mean values of Hb concentrations (M = 13.27 ±1.60 g/dL; F = 13.32±1.61g/dL; p = 0.93), total white cell count (M = 3.16±5.43 × 10(9)/L; F = 13.07±4.98 × 10(9)/L; p= 0.92), platelet count (M= 223.64± 64.21 × 10(9)/L; F = 226.69±80.83 × 10(9)/L; p = 0.81) and other parameters.


CONCLUSIONS
Mean values of full blood count parameters obtained in this study are comparable to reports from other studies in developing countries and could be a useful guide for neonatologists and stem cell transplant physicians in our geographical location.
Department of Haematology and Blood Transfusion, College of Medicine, University of Lagos.
Adediran
A
Adewumi
Department of Haematology and Blood Transfusion, College of Medicine, University of Lagos.
Adeyemo
A
Titilope A
Department of Haematology and Blood Transfusion, College of Medicine, University of Lagos.
Akinbami A
AA
Akinsegun
Department of Obstetrics and Gynaecology, Lagos State University College of Medicine, Ikeja, Nigeria.
Gbadegesin
G
Abidoye
Department of Haematology and Blood Transfusion, Lagos State University College of Medicine, Ikeja, Nigeria.
Uche
U
Ebele
Department of Haematology and Blood Transfusion, College of Medicine, University of Lagos.
Akanmu A
AA
Sulaimon
D000293:Adolescent; D000328:Adult; D001772:Blood Cell Count; D005260:Female; D005312:Fetal Blood / Q000166:cytology*; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D007231:Infant, Newborn; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D009549:Nigeria; D010976:Platelet Count; D011247:Pregnancy; D055815:Young Adult
D006454:Hemoglobins
Haemoglobin; cord blood; neonatologist; stem cell; umbilical cord