Staphylococcus aureus infection of the optic nerve.
A 71-year-old woman presented with painful vision loss in the right eye followed by ophthalmoplegia. Magnetic resonance imaging demonstrated optic nerve sheath enlargement and enhancement. Biopsy of the optic nerve sheath revealed purulent and necrotic material that was positive for methicillin-sensitive Staphylococcus aureus. The patient underwent enucleation of the right eye and was treated with systemic antibiotics with clinical stabilization. Imaging, pathological and treatment aspects of optic nerve sheath abscess are discussed.
Departments of Ophthalmology and Visual Sciences (SO, AYL, VKA, HEM), Medicine (OA-H), Pathology (AYL), and Radiology (SZ), University of Illinois College of Medicine, Chicago, Illinois; Department of Clinical Pharmacy and Outcomes Sciences (JAJ), South Carolina College of Pharmacy, Charleston, South Carolina; and Division of Infectious Disease (SM, MCP), University of Illinois College of Medicine, Chicago, Illinois.
Senad
S
Osmanovic
Omar M
OM
Al-Heeti
Amy Y
AY
Lin
Sean P
SP
Zivin
Julie Ann
JA
Justo
Stockton M
SM
Mayer
Vinay K
VK
Aakalu
Heather E
HE
Moss
Mahesh C
MC
Patel
D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009886:Ophthalmoplegia / Q000188:drug therapy / Q000209:etiology*; D009900:Optic Nerve / Q000473:pathology*; D013203:Staphylococcal Infections / Q000150:complications* / Q000188:drug therapy / Q000473:pathology*; D013211:Staphylococcus aureus / Q000472:pathogenicity*
D000900:Anti-Bacterial Agents