Enhancing of women functional status with metabolic syndrome by cardioprotective and anti-inflammatory effects of combined aerobic and resistance training.
These data describe the effects of combined aerobic plus resistance training (CT) with regards to risk factors of metabolic syndrome (MetS), quality of life, functional capacity, and pro- and anti-inflammatory cytokines in women with MetS. In this context, thirteen women (35.4 ± 6.2 yr) completed 10 weeks of CT consisting of three weekly sessions of ~60 min aerobic training (treadmill at 65-70% of reserve heart rate, 30 min) and resistance training (3 sets of 8-12 repetitions maximum for main muscle groups). Dependent variables were maximum chest press strength; isometric hand-grip strength; 30 s chair stand test; six minute walk test; body mass; body mass index; body adiposity index; waist circumference; systolic (SBP), diastolic and mean blood pressure (MBP); blood glucose; HDL-C; triglycerides; interleukins (IL) 6, 10 and 12, osteoprotegerin (OPG) and serum nitric oxide metabolite (NOx); quality of life (SF-36) and Z-Score of MetS. There was an improvement in muscle strength on chest press (p = 0.009), isometric hand-grip strength (p = 0.03) and 30 s chair stand (p = 0.007). There was a decrease in SBP (p = 0.049), MBP (p = 0.041), Z-Score of MetS (p = 0.046), OPG (0.42 ± 0.26 to 0.38 ± 0.19 ng/mL, p<0.05) and NOx (13.3 ± 2.3 µmol/L to 9.1 ± 2.3 µmol/L; p<0.0005). IL-10 displayed an increase (13.6 ± 7.5 to 17.2 ± 12.3 pg/mL, p < 0.05) after 10 weeks of training. Combined training also increased the perception of physical capacity (p = 0.011). This study endorses CT as an efficient tool to improve blood pressure, functional capacity, quality of life and reduce blood markers of inflammation, which has a clinical relevance in the prevention and treatment of MetS.
Catholic University of Brasilia, Graduation Program on Physical Education, Brasilia, Brazil.
Ramires Alsamir
RA
Tibana
Catholic University of Brasilia, Graduation Program on Physical Education, Brasilia, Brazil.
Dahan da Cunha
Dda C
Nascimento
Laboratory of Exercise Physiology, Faculty Estacio of Vitoria, Espirito Santo, Brazil.
Nuno Manuel Frade
NM
de Sousa
Catholic University of Brasilia, Graduation Program on Physical Education, Brasilia, Brazil.
Vinicius Carolino
VC
de Souza
University of Brasilia, Brasilia, Brazil.
João
J
Durigan
University of Brasilia, Brasilia, Brazil.
Amilton
A
Vieira
University of Brasilia, Brasilia, Brazil.
Martim
M
Bottaro
University of Brasilia, Brasilia, Brazil.
Otávio de Toledo
Ode T
Nóbrega
Catholic University of Brasilia, Graduation Program on Physical Education, Brasilia, Brazil; University of Brasilia, Brasilia, Brazil.
Jeeser Alves
JA
de Almeida
Department of Kinesiology and Nutrition Sciences of the University of Nevada, Las Vegas, Nevada, United States of America.
James Wilfred
JW
Navalta
Catholic University of Brasilia, Graduation Program on Physical Education, Brasilia, Brazil; Centro de Analises Proteomicas e Bioquimicas. Programa de Pos-Graduaçao em Ciencias Genomicas e Biotecnologia, Universidade Catolica de Brasilia, Brasilia, Brazil.
Octavio Luiz
OL
Franco
Catholic University of Brasilia, Graduation Program on Physical Education, Brasilia, Brazil.
Jonato
J
Prestes
D000328:Adult; D015415:Biomarkers / Q000097:blood; D001794:Blood Pressure; D005260:Female; D006321:Heart / Q000503:physiopathology*; D006801:Humans; D007249:Inflammation / Q000097:blood; D024821:Metabolic Syndrome / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D010809:Physical Fitness; D011788:Quality of Life; D055070:Resistance Training; D012307:Risk Factors
D015415:Biomarkers