A Neonate with CLOVES Syndrome.
Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi (CLOVE) syndrome is a recently delineated disorder that comprises vascular malformations (typically truncal), dysregulated adipose tissue, scoliosis, enlarged bony structures (typically of the legs) without progression, or distorting bony overgrowth. The name CLOVE was subsequently extended to CLOVES to emphasize the association with scoliosis/skeletal and spinal anomalies and seizures/central nervous system malformations. We herein report a very rare case of CLOVES syndrome with the findings of lipomatous overgrowth in the cheek (facial asymmetry), vascular malformation (hemangiomas), epidermal nevi (large port wine stains), and skeletal abnormalities (widened first interdigital space, dystrophia in the nail of the first digit of the right foot, and bilateral hypertrophy of the first digits of the feet).
Division of Neonatology, Department of Pediatrics, Erciyes University Faculty of Medicine, 38039 Kayseri, Turkey.
Dilek
0000-0002-7671-3010
D
Sarici
Division of Neonatology, Department of Pediatrics, Erciyes University Faculty of Medicine, 38039 Kayseri, Turkey.
Mustafa Ali
MA
Akin
Division of Neonatology, Department of Pediatrics, Erciyes University Faculty of Medicine, 38039 Kayseri, Turkey.
Selim
S
Kurtoglu
Department of Pediatrics, Erciyes University Faculty of Medicine, 38039 Kayseri, Turkey.
Filiz
F
Tubas
Division of Neonatology, Department of Pediatrics, Ufuk University Faculty of Medicine, 06500 Ankara, Turkey.
Serdar Umit
SU
Sarici