Effect of ultrasonography-guided botulinum toxin type a injection in holmes' tremor secondary to pontine hemorrhage: case report.
Holmes' tremor is a low-frequency rest and intentional tremor secondary to various insults, including cerebral ischemia, hemorrhage, trauma, or neoplasm. Pharmacologic treatment is usually unsuccessful, and some cases require surgical intervention. We report a rare case of Holmes' tremor secondary to left pontine hemorrhage in a 29-year-old Asian male patient who developed 1.6-Hz postural and rest tremor of the right hand. He responded markedly to ultrasonography-guided botulinum toxin type A injection. To our knowledge, this is the first report of Homes' tremor treated with ultrasonography-guided botulinum toxin type A injection with favorable results.
Department of Rehabilitation Medicine, Rehabilitation Hospital, National Rehabilitation Center, Seoul, Korea.
So-Yeon
SY
Ahn
Department of Rehabilitation Medicine, Rehabilitation Hospital, National Rehabilitation Center, Seoul, Korea.
Dong-A
DA
Kim
Division of Education & Public Relations, National Rehabilitation Center, Seoul, Korea.
Youn-Ok
YO
Park
Department of Rehabilitation Medicine, Rehabilitation Hospital, National Rehabilitation Center, Seoul, Korea.
Joon-Ho
JH
Shin
Botulinum toxins; Tremor; Ultrasonography