The novel use of bevacizumab and photodynamic therapy in the treatment of best disease.
OBJECTIVE
To report on the novel use of bevacizumab (Avastin) in combination with photodynamic therapy (PDT) for the treatment of Best disease with choroidal neovascularization.


METHODS
A 17-year-old girl with Best disease, choroidal neovascularization, and subretinal hemorrhage in the right eye was treated with bevacizumab and PDT.


RESULTS
The use of bevacizumab and PDT was associated with a change in vision from counting fingers to 20/25 and was well tolerated by the patient.


CONCLUSIONS
The use of bevacizumab and PDT in the management of Best disease seems to be a very effective method of treatment showing improvement in visual acuity.This is the first case to be reported in the literature of bevacizumab in combination with PDT for the treatment of choroidal neovascularization in Best disease.
From the *Faculty of Medicine and †Ottawa Eye Institute, University of Ottawa, Ottawa, Ontario, Canada.
Elliott
E
Brodbaker
Rani
R
Al Karmi
Bernard
B
Hurley
Stuart G
SG
Coupland