[Options and Limitations in Endovascular Therapy for Acute and Chronic Mesenteric Arterial Occlusions].
BACKGROUND
The significance of endovascular therapy for mesenteric ischaemia (MI) is being debated. Despite initially lower mortality and morbidity, inconsistent early and late results led to questions concerning indications and technical applications of the procedure.


METHODS
91 patients with MI underwent endovascular treatment in a period of 11 years. In 78 (85.7 %) patients a stent was deployed and in 13 (14.3 %) an angioplasty was performed, principally of the superior mesenteric artery (n = 81/91, 89 %). Follow-up consisted of a clinical and an ultrasound examination in all cases. Mean follow-up was 4.2 years. Our results were compared to those in the literature.


RESULTS
Endovascular treatment of the intestinal arteries accounted for 0.6 % of all vascular procedures. Seven of 91 patients (7.7 %) died after an initial PTA/stenting. The overall peri-interventional morbidity was 6.6 % (n = 6/91). Medium- to long-term complications were encountered in 20 patients (22 %), primarily during the first year (85 %). Six of 91 patients developed an in-stent stenosis (6.6 %) and 14/91 patients (15.4 %) stent occlusion. Additionally 2 dislocated stents (2.2 %) and an arterial perforation with bleeding into the mesentery (1.1 %) were seen. Although 3 of these 20 patients were successfully treated with an additional PTA or stenting (15.0 %; n = 3/91, 3.3 %), surgical conversion was necessary in 9 (n = 9/20, 45 %; n = 9/91, 9.9 %). The postoperative mortality was respectively 22.2 % (n = 2/9; n = 2/91, 2.2 %). In the case of acute MI, endovascular procedures are only indicated for patients without peritonitis. In chronic MI, the indication for endovascular treatment depends on the type of occlusion and the vascular anatomy. Despite favourable early results, the outcome of endovascular treatment deteriorates with time reaching a 1-year patency rate of 63 % in a multicentre analysis. This leads to secondary procedures in 30 %. A surgical conversion carries a high mortality.


CONCLUSIONS
The endovascular treatment of intestinal artery disease cannot be considered the treatment of choice, it is rather an alternative method in patients with functional or local contraindications to surgery. Life-long follow-up is necessary to prevent stent complications with fatal consequences. A prospective randomised study concerning the evaluation of the advantages and disadvantages of surgical and endovascular therapy of intestinal artery occlusive disease is required.
Gefäßmedizin, Helios-Klinik, Krefeld, Deutschland.
B
B
Luther
Klinik für Allgemein-, Viszeral- & Gefäßchirurgie, Universitätsklinikum Magdeburg A. ö. R., Deutschland.
F
F
Meyer
Gefäßmedizin, Helios-Klinik, Krefeld, Deutschland.
A
A
Mamopoulos
Gefäßmedizin, Helios-Klinik, Krefeld, Deutschland.
A
A
Zapenko
Radiologie, Helios-Klinik, Krefeld, Deutschland.
R
R
Doerbecker
Allgemein- & Viszeralchirurgie, Helios-Klinik, Krefeld, Deutschland.
C
C
Wullstein
Gefäßmedizin, Helios-Klinik, Krefeld, Deutschland.
K
K
Kroeger
Radiologie, Helios-Klinik, Krefeld, Deutschland.
M
M
Katoh
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D002648:Child; D002908:Chronic Disease; D061887:Conversion to Open Surgery / Q000706:statistics & numerical data; D057510:Endovascular Procedures / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D021621:Imaging, Three-Dimensional; D015994:Incidence; D008297:Male; D008638:Mesenteric Arteries / Q000601:surgery; D065666:Mesenteric Ischemia / Q000401:mortality / Q000601:surgery*; D008641:Mesenteric Vascular Occlusion / Q000401:mortality / Q000601:surgery*; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality; D016019:Survival Analysis; D014057:Tomography, X-Ray Computed; D055815:Young Adult