Catalyst-free synthesis of highly biologically active 5-arylidene rhodanine and 2,4-thiazolidinedione derivatives using aldonitrones in polyethylene glycol.
A green, efficient synthesis of 5-arylidene rhodanine and 2,4-thiazolidinedione derivatives without using any external catalyst in polyethylene glycol (PEG) at 80°C has been described. Reaction procedure is very simple, short, and obtained yields are very high.
Department of Chemistry, Punjabi University, Patiala, Punjab 147002, India.
Dhruva
D
Kumar
Department of Chemistry, Punjabi University, Patiala, Punjab 147002, India.
Suresh
S
Narwal
Department of Chemistry, Punjabi University, Patiala, Punjab 147002, India.
Jagir S
JS
Sandhu