Intraretinal deposition of triamcinolone acetonide after treatment of diabetic macular edema.
OBJECTIVE
To report a case of intraretinal triamcinolone acetonide crystal deposition visualized both clinically and on optical coherence tomography after intravitreal injection for diabetic macular edema refractory to focal/grid laser treatment.


METHODS
Observational case report. A 46-year-old man with severe bilateral diabetic macular edema underwent focal/grid laser therapy, Avastin (Genetech, Inc., South San Francisco, CA) injections, and multiple intravitreal triamcinolone acetonide treatments but remained refractory to treatment.


RESULTS
Visual acuity continued to worsen, and clinical and optical coherence tomography examination revealed scattered hyperreflective deposits throughout the retina.


CONCLUSIONS
Intravitreal triamcinolone acetonide can deposit within the retina after treatment of refractory diabetic macular edema.
From the New England Eye Center, Tufts Medical Center, Boston, Massachusetts.
Varsha
V
Manjunath
Jay S
JS
Duker