Allergic contact dermatitis to 2-octyl cyanoacrylate.
Cyanoacrylates are widely used as topical skin adhesives in emergency departments, clinics, and operating rooms. We report 4 patients who developed allergic contact dermatitis (ACD) following postsurgical closure with 2-octyl cyanoacrylate. These patients were challenged with a novel method of use testing to confirm sensitivity to 2-octyl cyanoacrylate. The popularity of skin adhesives makes this emerging allergen worthy of examination. It is possible that cyanoacrylate allergy currently is underrecognized.
Department of Dermatology, San Antonio Military Medical Center South, 2200 Bergquist Dr, Ste 1, Lackland AFB, TX 78236, USA. caseybowen.2@us.af.mil.
Casey
C
Bowen
Jeff
J
Bidinger
Chad
C
Hivnor
Aaron
A
Hoover
Jeffrey S
JS
Henning
D000287:Administration, Topical; D000328:Adult; D000368:Aged; D003487:Cyanoacrylates / Q000008:administration & dosage / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage; D006634:Histamine H1 Antagonists / Q000008:administration & dosage; D006801:Humans; D006919:Hydroxyzine / Q000008:administration & dosage*; D010328:Patch Tests / Q000379:methods; D011183:Postoperative Complications / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D013514:Surgical Procedures, Operative / Q000379:methods; D014014:Tissue Adhesives / Q000008:administration & dosage / Q000009:adverse effects*; D016896:Treatment Outcome; D014222:Triamcinolone Acetonide / Q000008:administration & dosage*
D003487:Cyanoacrylates; D005938:Glucocorticoids; D006634:Histamine H1 Antagonists; D014014:Tissue Adhesives; D006919:Hydroxyzine; C100832:octyl 2-cyanoacrylate; D014222:Triamcinolone Acetonide