Gender identity disputed in the court of justice: a story of female to male sexual transformation in the hellenistic period, described by Diodorus Siculus.
Cases of sexual reassignment in Greco-Roman antiquity, presenting as a pubertal female to male gender transformation, are described in the "classical"literature. Textual evidence concerning a case of androgynism, garnered by Diodorus Siculus, among other similar accounts, as an odd story of gender dispute in a court of justice, is provided in the present study. A medical interpretation of the data pertaining to this case has been attempted and is herein reported. The spontaneous virilization and post-pubertal gender inversion of the specific individual appears to have been caused by a defect either in 5α-reductase type 2 or in 17β hydroxysteroid dehydrogenase genes and consequent deficient enzymatic activity.
Anastasia K
AK
Armeni
Vasiliki
V
Vasileiou
George
G
Markantes
Christina
C
Damoulari
Angelina
A
Mandrapilia
Fotini A
FA
Kosmopoulou
Varvara
V
Keramisanou
Danai
D
Georgakopoulou
Neoklis A
NA
Georgopoulos
D015067:17-Hydroxysteroid Dehydrogenases / Q000172:deficiency / Q000235:genetics; D013741:3-Oxo-5-alpha-Steroid 4-Dehydrogenase / Q000172:deficiency / Q000235:genetics; D058531:46, XX Testicular Disorders of Sex Development / Q000175:diagnosis / Q000266:history*; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005783:Gender Identity; D018645:Greek World; D049690:History, Ancient; D006801:Humans; D007603:Jurisprudence / Q000266:history; D008297:Male; D008393:Marriage / Q000266:history; D055815:Young Adult
D015067:17-Hydroxysteroid Dehydrogenases; C044256:3 (or 17)-beta-hydroxysteroid dehydrogenase; D013741:3-Oxo-5-alpha-Steroid 4-Dehydrogenase