Prostatic surgery associated acute kidney injury.
Acute kidney injury (AKI) is associated with extended hospital stays, high risks of in-hospital and long-term mortality, and increased risk of incident and progressive chronic kidney disease. Patients with urological diseases are a high-risk group for AKI owing to the coexistence of obstructive uropathy, older age, and preexistent chronic kidney disease. Nonetheless, precise data on the incidence and outcomes of postoperative AKI in urological procedures are lacking. Benign prostatic hyperplasia and prostate cancer are common diagnoses in older men and are frequently treated with surgical procedures. Whereas severe AKI after prostate surgery in general appears to be unusual, AKI associated with transurethral resection of the prostate (TURP) syndrome and with rhabdomyolysis (RM) after radical prostatectomy have been frequently described. The purpose of this review is to discuss the current knowledge regarding the epidemiology, risk factors, outcomes, prevention, and treatment of AKI associated with prostatic surgery. The mechanisms of TURP syndrome and RM following prostatic surgeries will be emphasized.
Elerson Carlos Costalonga, Verônica Torres Costa e Silva, Renato Caires, James Hung, Luis Yu, Emmanuel A Burdmann, Department of Nephrology, Cancer Institute of São Paulo, University of São Paulo Medical School, São Paulo 01246-000, Brazil.
Elerson Carlos
EC
Costalonga
Elerson Carlos Costalonga, Verônica Torres Costa e Silva, Renato Caires, James Hung, Luis Yu, Emmanuel A Burdmann, Department of Nephrology, Cancer Institute of São Paulo, University of São Paulo Medical School, São Paulo 01246-000, Brazil.
Verônica Torres
VT
Costa E Silva
Elerson Carlos Costalonga, Verônica Torres Costa e Silva, Renato Caires, James Hung, Luis Yu, Emmanuel A Burdmann, Department of Nephrology, Cancer Institute of São Paulo, University of São Paulo Medical School, São Paulo 01246-000, Brazil.
Renato
R
Caires
Elerson Carlos Costalonga, Verônica Torres Costa e Silva, Renato Caires, James Hung, Luis Yu, Emmanuel A Burdmann, Department of Nephrology, Cancer Institute of São Paulo, University of São Paulo Medical School, São Paulo 01246-000, Brazil.
James
J
Hung
Elerson Carlos Costalonga, Verônica Torres Costa e Silva, Renato Caires, James Hung, Luis Yu, Emmanuel A Burdmann, Department of Nephrology, Cancer Institute of São Paulo, University of São Paulo Medical School, São Paulo 01246-000, Brazil.
Luis
L
Yu
Elerson Carlos Costalonga, Verônica Torres Costa e Silva, Renato Caires, James Hung, Luis Yu, Emmanuel A Burdmann, Department of Nephrology, Cancer Institute of São Paulo, University of São Paulo Medical School, São Paulo 01246-000, Brazil.
Emmanuel A
EA
Burdmann
Acute kidney injury; Prostate cancer; Prostatectomy; Prostatic hyperplasia; Rhabdomyolysis; Transurethral resection of the prostate