Exudative retinal detachment in castleman disease.
OBJECTIVE
To describe the course of a case of Castleman disease (CD) that presented with visual symptoms and retinal disease.


METHODS
Clinical examination, fundus photography, and fluorescein and indocyanine green angiography were used to characterize the presence of bilateral exudative retinal detachments in a patient who was subsequently identified as having systemic lymphadenopathy.


RESULTS
After an extensive medical workup including CT scans, blood testing, and a lymph node and renal biopsy, the patient was diagnosed with CD. Steroids were administered to treat CD. During the course of treatment, the patient developed renal failure, which was successfully treated with plasmapheresis. Four weeks later, the bilateral retinal detachments had resolved without local treatment.


CONCLUSIONS
Exudative retinal detachments as manifestations of CD may be observed under systemic treatment for resolution before considering local therapy.
From the *Department of Ophthalmology, and †Department of Pathology, Columbia University Medical Center, New York, New York.
Gaetano R
GR
Barile
Nora
N
Khatib
Song Eun
SE
Lee
Elona
E
Dhrami-Gavazi
Reza
R
Iranmanesh
Michael B
MB
Stokes