Identification of 19 phthalic acid esters in dairy products by gas chromatography with mass spectrometry.
A detection method for 19 kinds of phthalic acid ester compounds analyzed by n-hexane/ether/acetonitrile 1:7:8 v/v/v mixed solvent extraction, quick, easy, cheap, effective, rugged, and safe purification and internal standard method of quantitative gas chromatography with mass spectrometry was established. This method can effectively remove interfering materials, such as lipids, fatty acids, and pigments, from dairy products. The 19 kinds of phthalic acid ester compounds were within a 0.025-0.2 mg/kg range, the recovery rate was 65.2-125.7%, relative standard deviation was 7.9-15.4% (n = 6), and the limit of detection was 0.005-0.02 mg/kg. Concentrations of the 19 kinds of phthalic acid ester compounds ranged between 0.01 and 0.12 mg/kg in ten dairy materials and 20 dairy products. The established method is simple, rapid, accurate, and highly sensitive.
Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Pinggu
P
Wu
Chenggang
C
Cai
Dajin
D
Yang
Liyuan
L
Wang
Yan
Y
Zhou
Xianghong
X
Shen
Bingjie
B
Ma
Jun
J
Tang
D003611:Dairy Products / Q000032:analysis*; D004952:Esters / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D057230:Limit of Detection; D010795:Phthalic Acids / Q000032:analysis* / Q000737:chemistry; D012015:Reference Standards; D015203:Reproducibility of Results
D004952:Esters; D010795:Phthalic Acids
Dairy products; Gas chromatography; Mass spectrometry; Phthalate esters