Increased Epicardial Adipose Tissue Thickness is Associated With Angiographic Thrombus Burden in the Patients With Non-ST-Segment Elevation Myocardial Infarction.
We aimed to evaluate the relation among epicardial adipose tissue (EAT) thickness, angiographic presence of thrombus, and the no-reflow in the patients with non-ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. The study population consisted of 229 patients. The EAT thickness and neutrophil to lymphocyte ratio (NLR) were significantly higher in the patients with coronary thrombus than in those without coronary thrombus (6.1 ± 1.1 vs 5.1 ± 1.3 mm, P < .001 and 3.4 ± 0.9 vs 2.5 ± 0.7, P < .001, respectively) and in the patients with no-reflow compared to patients with reflow. The EAT thickness was found to be correlated positively with the degree of the thrombus burden, NLR, and waist circumference and negatively with high-density lipoprotein cholesterol. Multivariate logistic regression analysis demonstrated that EAT thickness and NLR independently predicted coronary thrombus formation and no-reflow. We have suggested that EAT can play an important role in the pathophysiology of coronary thrombus formation and the no-reflow.
Department of Cardiology, Faculty of Medicine, Erzincan University, Erzincan, Turkey eftalka@yahoo.com.
Eftal Murat
EM
Bakirci
Department of Cardiology, Faculty of Medicine, Erzincan University, Erzincan, Turkey.
Husnu
H
Degirmenci
Department of Cardiology, Faculty of Medicine, Rize University, Rize, Turkey.
Hakan
H
Duman
Department of Cardiology, Aksaray State Hospital, Aksaray, Turkey.
Sinan
S
Inci
Department of Cardiology, Faculty of Medicine, Erzincan University, Erzincan, Turkey.
Hikmet
H
Hamur
Department of Cardiology, Faculty of Medicine, Erzincan University, Erzincan, Turkey.
Mutlu
M
Buyuklu
Department of Cardiology, Faculty of Medicine, Erzincan University, Erzincan, Turkey.
Gokhan
G
Ceyhun
Department of Cardiology, Faculty of Medicine, Erzincan University, Erzincan, Turkey.
Ergun
E
Topal
D000273:Adipose Tissue / Q000000981:diagnostic imaging*; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000601:surgery; D062645:Percutaneous Coronary Intervention; D010496:Pericardium / Q000000981:diagnostic imaging*; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000601:surgery; D014463:Ultrasonography
coronary thrombus; epicardial adipose tissue; no-reflow; non-ST-segment elevation myocardial infarction; percutaneous coronary intervention