[Relationship between visceral fat and development of colorectal neoplasms using computed tomographic colonography and adipocytokine levels].
We evaluated the relationship between colorectal neoplasms and visceral obesity using computed tomographic colonography and adipocytokine levels. We included 123 patients and classified them into four groups as per computed tomographic colonography: no lesion (NL; n=40), adenomatous polyp (polyp; n=41), early colorectal cancer (eCRC; n=21), and advanced CRC (aCRC; n=21). We also measured the patients' serum metabolic markers and adipocytokine levels. The visceral adiposity index in the polyp and eCRC groups was significantly higher than that in the NL group. Visceral obesity is an important risk factor for the development of colonic polyps. Computed tomographic colonography could be a useful examination technique not only for diagnosis of colorectal neoplasms but also for simultaneous evaluation of visceral obesity.
Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School.
Yoshiki
Y
Kimura
Hiroshi
H
Matsumoto
Motoyasu
M
Oosawa
Minoru
M
Fujita
Ken-Ichi
K
Tarumi
Tomoari
T
Kamada
Akiko
A
Shiotani
Ken
K
Haruma
D000368:Aged; D023881:Colonography, Computed Tomographic / Q000379:methods*; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D005260:Female; D006801:Humans; D050152:Intra-Abdominal Fat / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009765:Obesity / Q000150:complications*; D012307:Risk Factors