The significance for epidemiological studies anti-measles antibody detection examined by enzyme immunoassay (EIA) and plaque reduction neutralization test (PRNT).
The paper discusses the role of anti-measles antibodies for protection and significance for epidemiological studies determination of antibodies by different serological methods. The comparison of anti-measles virus antibodies levels measured by enzyme immunoassay (EIA) and Plaque Reduction Neutralization Test (PRNT) was described. It was found that the 200 mIU/ml of anti-measles activity measured by PRNT (level protection against symp- tomatic disease) is equivalent of 636 mIU/ml measured by EIA (Enzygnost®Anti-Measles Virus/IgG, Simens).
Joanna
J
Siennicka
Agnieszka
A
Częścik
Agnieszka
A
Trzcińska
D000914:Antibodies, Viral / Q000097:blood*; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods; D008457:Measles / Q000276:immunology*; D008459:Measles virus / Q000276:immunology*; D009500:Neutralization Tests; D012680:Sensitivity and Specificity; D010948:Viral Plaque Assay / Q000379:methods*
D000914:Antibodies, Viral