Factors influencing contrast sensitivity function in myopic eyes.
OBJECTIVE
To evaluate the factors affecting the area under the log contrast sensitivity function (AULCSF) in healthy myopic eyes.


METHODS
We retrospectively examined 201 eyes of 201 consecutive subjects (age, 31.8 ± 7.4 years (mean ± standard deviation)) with myopic refractive errors of -1.25 to -8.25 diopters (D). From the contrast sensitivity data, the area under the log contrast sensitivity function (AULCSF) was calculated. Stepwise multiple regression analysis was used to assess the factors affecting the AULCSF.


RESULTS
The mean AULSCF was 1.09 ± 0.09 (0.89 to 1.55). Explanatory variables relevant to the AULCSF were, in order of influence, the objective scattering index (OSI) (p = 0.018, partial regression coefficient B =  -0.032) and logMAR CDVA (p = 0.022, B =  -0.209) (adjusted R(2) = 0.231). No significant correlation was seen with other clinical factors such as gender, manifest refraction, pupil size, lens density, corneal HOAs, or ocular HOAs.


CONCLUSIONS
Although the great majority of the variance remains unexplained, eyes with lower OSI and better CDVA are more predisposed to show higher contrast sensitivity function. These results indicate that not only CDVA but also intraocular forward scattering may play some role in predicting the contrast sensitivity function in myopic subjects.
Department of Ophthalmology, University of Kitasato School of Medicine, Sagamihara, Kanagawa, Japan.
Kazutaka
K
Kamiya
Department of Ophthalmology, University of Kitasato School of Medicine, Sagamihara, Kanagawa, Japan.
Kimiya
K
Shimizu
Department of Ophthalmology, University of Kitasato School of Medicine, Sagamihara, Kanagawa, Japan.
Ayaka
A
Iijima
Department of Ophthalmology, University of Kitasato School of Medicine, Sagamihara, Kanagawa, Japan.
Hidenaga
H
Kobashi
D000293:Adolescent; D000328:Adult; D015350:Contrast Sensitivity / Q000502:physiology*; D003315:Cornea / Q000503:physiopathology*; D005123:Eye / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007908:Lens, Crystalline / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology*; D012029:Refraction, Ocular / Q000502:physiology; D012030:Refractive Errors / Q000503:physiopathology*; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology*; D055815:Young Adult