How could haloalkaliphilic microorganisms contribute to biotechnology?
Haloalkaliphiles are microorganisms requiring Na(+) concentrations of at least 0.5 mol·L(-1) and an alkaline pH of 9 for optimal growth. Their unique features enable them to make significant contributions to a wide array of biotechnological applications. Organic compatible solutes produced by haloalkaliphiles, such as ectoine and glycine betaine, are correlated with osmoadaptation and may serve as stabilizers of intracellular proteins, salt antagonists, osmoprotectants, and dermatological moisturizers. Haloalkaliphiles are an important source of secondary metabolites like rhodopsin, polyhydroxyalkanoates, and exopolysaccharides that play essential roles in biogeocycling organic compounds. These microorganisms also can secrete unique exoenzymes, including proteases, amylases, and cellulases, that are highly active and stable in extreme haloalkaline conditions and can be used for the production of laundry detergent. Furthermore, the unique metabolic pathways of haloalkaliphiles can be applied in the biodegradation and (or) biotransformation of a broad range of toxic industrial pollutants and heavy metals, in wastewater treatment, and in the biofuel industry.
a Graduate School, Chinese Academy of Agricultural Sciences, Beijing 100081, People's Republic of China.
Baisuo
B
Zhao
Yanchun
Y
Yan
Shulin
S
Chen
D001419:Bacteria / Q000201:enzymology; D018407:Bacterial Physiological Phenomena; D001622:Betaine / Q000378:metabolism; D001673:Biodegradation, Environmental; D056804:Biofuels; D001692:Biological Transport; D001709:Biotechnology; D001711:Biotransformation; D006216:Halobacteriaceae / Q000201:enzymology / Q000502:physiology*; D053858:Metabolic Networks and Pathways; D055049:Salt Tolerance; D064210:Secondary Metabolism; D012965:Sodium Chloride
D056804:Biofuels; D001622:Betaine; D012965:Sodium Chloride
biodegradation and (or) biotransformation; biodégradation et (or) biotransformation; biofuel industry; compatible solutes; exoenzymes; haloalcalophile; haloalkaliphile; industrie des biocarburants; métabolites secondaires; secondary metabolites; solutés compatibles