Pd(II)-catalyzed C-H arylation of aryl and benzyl Weinreb amides.
The first example of palladium-catalyzed ortho-C-H arylation of aryl and benzyl Weinreb amides was developed, in which HOTf was used as a key promoter. This method exhibits good functional group tolerance, a broad substrate scope of both Weinreb amides and aryl iodides, high mono-selectivity and mild reaction conditions.
Department of Chemistry, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026, China. xswang77@ustc.edu.cn.
Yan
Y
Wang
Kai
K
Zhou
Quan
Q
Lan
Xi-Sheng
XS
Wang