The use of the fractional CO2 laser resurfacing in the treatment of photoaging in Asians: five years long-term results.
OBJECTIVE
The purpose of this clinical paper is to explore the therapeutic effects, healing times, adverse effects, and maintenance periods of using a CO2 fractional laser in the treatment of photoaging in Asian skin.


METHODS
One fractional CO2 laser procedure was performed on the full face in 56 patients with photoaging. Based on the Dover scoring system, we evaluated the degree of skin aging before treatment and at one-month post laser and at five years post laser therapy in 30 of the patients. Statistical analysis was performed by the Wilcoxon's method.


RESULTS
Thirty of the treated patients have had follow-up for 5 years at this time. The photoaging scores in these thirty patients were significantly changed (P < 0.01) at one month, one year, and five years after the fractional laser treatment, as compared with their baseline. Adverse events seen during this analysis were found to be minimal and not of clinical significance.


CONCLUSIONS
Fractional CO2 laser resurfacing in the treatment of photoaging in Asians is a useful modality with results, for the first time, being shown to have continued efficacy for up to 5 years.
The People's Hospital of Hunan Province, Department of Plastic & Laser Aesthetic Surgery, 1st Affiliated Hospital of Hunan Normal University, Chang-Sha, Hunan, 410005, P.R. China.
Jun
J
Tan
Ying
Y
Lei
Hua-Wei
HW
Ouyang
Michael H
MH
Gold
D000328:Adult; D000368:Aged; D044466:Asian People; D002681:China; D005145:Face; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000295:instrumentation*; D054020:Lasers, Gas / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D015595:Skin Aging / Q000208:ethnology* / Q000473:pathology*; D013997:Time Factors; D016896:Treatment Outcome
UltraPulse fractional CO2 laser resurfacing; laser; photoaging; wrinkles