Rosiglitazone toxicity: accidental overdose leading to macular edema.
OBJECTIVE
To highlight the clinical effects of rosiglitazone overdose.


METHODS
Case report, observational.


RESULTS
A 60-year-old Chinese man accidentally ingested 20 mg rosiglitazone. His usual dose was 2 mg once in the morning. Complications of drug overdose were monitored. He consequently developed right mild macular edema. This resolved spontaneously without laser treatment. No systemic toxicity, hypoglycemia, or peripheral edema was observed.


CONCLUSIONS
Rosiglitazone overdose causes acute macular edema that resolves spontaneously.
From the Department of Ophthalmology, National University Hospital, Singapore.
Harold K
HK
Choi
Gavin S
GS
Tan
Gangadhara
G
Sundar