Successful combined photodynamic and intravitreal avastin therapy for subfoveal choroidal neovascularization in a child.
OBJECTIVE
To report the results of combined photodynamic therapy with verteporfin and intravitreal Avastin delivered on the same day in the treatment of juvenile subfoveal choroidal neovascularization.


METHODS
Photodynamic therapy with Visudyne at standard fluence rates and intravitreal Avastin were successfully completed under topical anesthesia in a single day treatment session in an 11-year-old girl with subfoveal choroidal neovascularization.


METHODS
A cooperative 11-year-old girl noted sudden vision loss in her right eye with a previous history of a small nonspecific extrafoveal inferior scar, and was noted to have developed an acute subfoveal choroidal neovascular membrane.


RESULTS
The subfoveal choroidal neovascular membrane regressed without any additional therapy or recurrence over an 18-month period and with recovery of 20/20 vision. There were diffuse mild pigmentary changes in the region of the previous choroidal neovascularization.


CONCLUSIONS
Choroidal neovascularization in juvenile patients may respond well to a combined photodynamic and intravitreal Avastin therapy delivered in a single day session with excellent recovery of vision and without the need for frequent multiple treatments, which would be difficult in this age group.
From the *Division of Ophthalmology, Department of Surgery, University of Hawaii School of Medicine, Honolulu; and †The Retina Center at Pali Momi, an affiliation of Hawaii Pacific Health.
Gregg T
GT
Kokame
John H
JH
Drouilhet