A hierarchy of intrinsic timescales across primate cortex.
Specialization and hierarchy are organizing principles for primate cortex, yet there is little direct evidence for how cortical areas are specialized in the temporal domain. We measured timescales of intrinsic fluctuations in spiking activity across areas and found a hierarchical ordering, with sensory and prefrontal areas exhibiting shorter and longer timescales, respectively. On the basis of our findings, we suggest that intrinsic timescales reflect areal specialization for task-relevant computations over multiple temporal ranges.
1] Center for Neural Science, New York University, New York, New York, USA. [2] Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut, USA.
John D
JD
Murray
1] Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut, USA. [2] School of Engineering and Science, Jacobs University, Bremen, Germany.
Alberto
A
Bernacchia
Department of Neurobiology, The University of Chicago, Chicago, Illinois, USA.
David J
DJ
Freedman
1] Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, México D.F., Mexico. [2] El Colegio Nacional, México D.F., Mexico.
Ranulfo
R
Romo
1] Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, California, USA. [2] Department of Psychology, University of California, Berkeley, Berkeley, California, USA.
Jonathan D
JD
Wallis
1] NYU-ECNU Institute of Brain and Cognitive Science, NYU Shanghai, Shanghai, China. [2] Department of Anatomy and Neurobiology, Washington University in St. Louis, St. Louis, Missouri, USA.
Xinying
X
Cai
Department of Anatomy and Neurobiology, Washington University in St. Louis, St. Louis, Missouri, USA.
Camillo
C
Padoa-Schioppa
1] Department of Neurobiology and Anatomy, University of Rochester, Rochester, New York, USA. [2] Center for Visual Science, University of Rochester, Rochester, New York, USA.
Tatiana
T
Pasternak
Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut, USA.
Hyojung
H
Seo
Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut, USA.
Daeyeol
000000033474019X
D
Lee
1] Center for Neural Science, New York University, New York, New York, USA. [2] Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut, USA. [3] NYU-ECNU Institute of Brain and Cognitive Science, NYU Shanghai, Shanghai, China.
Xiao-Jing
XJ
Wang
D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D002540:Cerebral Cortex / Q000502:physiology*; D005260:Female; D008251:Macaca; D008297:Male; D010775:Photic Stimulation / Q000379:methods*; D011323:Primates; D011597:Psychomotor Performance / Q000502:physiology*; D013997:Time Factors