Chemical and medicinal versatility of dithiocarbamates: an overview.
Dithiocarbamates are considered as the simplest occurring organosulfur compounds exhibiting diverse chemical and medicinal versatility. Dithiocarbamates have been used as pesticide in the 20(th) century but thereafter they have attracted the interest of medicinal chemists due to their metal binding capacity. Recently a variety of chemical and medicinal properties of dithiocarbamates have been explored other than metal binding capacity. This review collectively describes the most significant chemical and medicinal properties of dithiocarbamate derivatives reported over the last decade.
Veenu
V
Bala
Gopal
G
Gupta
Medicinal and Process Chemistry Division, Central Drug Research Institute, Sector 10, Jankipuram ext., Lucknow, Uttar Pradesh 226031, India. vlscdri1@rediffmail.com.
Vishnu L
VL
Sharma
D000818:Animals; D019380:Anti-HIV Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D055808:Drug Discovery; D006678:HIV / Q000187:drug effects; D006801:Humans; D009181:Mycoses / Q000188:drug therapy; D009369:Neoplasms / Q000188:drug therapy; D013089:Spermatocidal Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D013859:Thiocarbamates / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*
D019380:Anti-HIV Agents; D000935:Antifungal Agents; D000970:Antineoplastic Agents; D013089:Spermatocidal Agents; D013859:Thiocarbamates