Acute heart failure: acute cardiorenal syndrome and role of aggressive decongestion.
Congestion and acute renal dysfunction are at the center of acute heart failure (HF) syndromes. Acute cardiorenal syndrome, which refers to worsening of renal function in a patient with acute HF syndrome, is partly related to venous congestion and high renal afterload. Aggressive decongestion improves renal and myocardial flow and ventricular loading conditions, potentially resulting in reduced HF progression, rehospitalization, and mortality. High-dose diuretic therapy remains the mainstay therapy. Ultrafiltration and inotropic therapy are useful in the subgroup of patients with a low-output state and diuretic resistance.
Department of Medicine, Cardiovascular Section, Louisiana State University, New Orleans, Louisiana.
Elias B
EB
Hanna
Eliana
E
Hanna Deschamps
D000208:Acute Disease; D002316:Cardiotonic Agents / Q000627:therapeutic use; D004232:Diuretics / Q000627:therapeutic use; D004351:Drug Resistance; D006333:Heart Failure / Q000150:complications* / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy*; D013577:Syndrome
D002316:Cardiotonic Agents; D004232:Diuretics