Particle therapy for non-small cell lung tumors: where do we stand? A systematic review of the literature.
This review article provides a systematic overview of the currently available evidence on the clinical effectiveness of particle therapy for the treatment of non-small cell lung cancer and summarizes findings of in silico comparative planning studies. Furthermore, technical issues and dosimetric uncertainties with respect to thoracic particle therapy are discussed.
Department of Radiation Oncology (MAASTRO Clinic), GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre , Maastricht , Netherlands.
Krista C J
KC
Wink
Department of Radiation Oncology (MAASTRO Clinic), GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre , Maastricht , Netherlands.
Erik
E
Roelofs
Department of Radiation Oncology, Hospital of the University of Pennsylvania , Philadelphia, PA , USA.
Timothy
T
Solberg
Department of Radiation Oncology, Hospital of the University of Pennsylvania , Philadelphia, PA , USA.
Liyong
L
Lin
Department of Radiation Oncology, Hospital of the University of Pennsylvania , Philadelphia, PA , USA.
Charles B
CB
Simone
OncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf , Dresden , Germany.
Annika
A
Jakobi
OncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf , Dresden , Germany ; German Cancer Consortium (DKTK) Dresden and German Cancer Research Center (DKFZ) , Heidelberg , Germany.
Christian
C
Richter
Department of Radiation Oncology (MAASTRO Clinic), GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre , Maastricht , Netherlands.
Philippe
P
Lambin
Department of Radiation Oncology (MAASTRO Clinic), GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre , Maastricht , Netherlands.
Esther G C
EG
Troost
C-ion; IMPT; NSCLC; PBS; PSPT; photon; proton; radiotherapy