Acute respiratory distress caused by Neosartorya udagawae.
We describe the first reported case of acute respiratory distress syndrome (ARDS) attributed to Neosartorya udagawae infection. This mold grew rapidly in cultures of multiple respiratory specimens from a previously healthy 43-year-old woman. Neosartorya spp. are a recently recognized cause of invasive disease in immunocompromised patients that can be mistaken for their sexual teleomorph, Aspergillus fumigatus. Because the cultures were sterile, phenotypic identification was not possible. DNA sequencing of ITS, calmodulin and β-tubulin genes supported identification of Neosartorya udagawae. Our case is the first report of ARDS associated with Neosartorya sp. infection and defines a new clinical entity.
Department of Medicine, Division of Infectious Disease, University of Illinois School of Medicine, Peoria, IL 61604, USA.
John J
JJ
Farrell
Department of Medicine, Division of Infectious Disease, University of Illinois School of Medicine, Peoria, IL 61604, USA.
Douglas J
DJ
Kasper
Department of Medicine, Division of Pulmonary Medicine, Saint Francis Medical Center, Peoria, IL 61604, USA.
Deepak
D
Taneja
Department of Laboratory Medicine, Saint Francis Medical Center, Peoria, IL 61604, USA.
Sudhakar
S
Baman
Department of Laboratory Medicine, Saint Francis Medical Center, Peoria, IL 61604, USA.
Lindsay M
LM
O׳Rourke
Ibis Biosciences, an Abbott Company, Carlsbad, CA 92008, USA.
Kristin S
KS
Lowery
Ibis Biosciences, an Abbott Company, Carlsbad, CA 92008, USA.
Rangarajan
R
Sampath
Departments of Medicine, Pharmacology and Molecular Microbiology Case Western Reserve University, Cleveland, OH 44106, USA ; Research Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH 44106, USA.
Robert A
RA
Bonomo
Bacterial Foodborne Pathogens and Mycology, National Center for Agricultural Utilization Research, US Department of Agriculture, 1815 North University Street, Peoria, IL 61604, USA.
Stephen W
SW
Peterson
ARDS; Aspergillosis; Diagnostic mycology; Molecular microbiology