The National Institute of Diabetes and Digestive and Kidney Diseases Central Repositories: a valuable resource for nephrology research.
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Central Repositories, part of the National Institutes of Health (NIH), are an important resource available to researchers and the general public. The Central Repositories house samples, genetic data, phenotypic data, and study documentation from >100 NIDDK-funded clinical studies, in areas such as diabetes, digestive disease, and liver disease research. The Central Repositories also have an exceptionally rich collection of studies related to kidney disease, including the Modification of Diet in Renal Disease landmark study and recent data from the Chronic Renal Insufficiency Cohort and CKD in Children Cohort studies. The data are carefully curated and linked to the samples from the study. The NIDDK is working to make the materials and data accessible to researchers. The Data Repositories continue to improve flexible online searching tools that help researchers identify the samples or data of interest, and NIDDK has created several different paths to access the data and samples, including some funding initiatives. Over the past several years, the Central Repositories have seen steadily increasing interest and use of the stored materials. NIDDK plans to make more collections available and do more outreach and education about use of the datasets to the nephrology research community in the future to enhance the value of this resource.
Division of Kidney, Urologic and Hematologic Diseases, and rebekah.rasooly@nih.gov.
Rebekah S
RS
Rasooly
Division of Diabetes, Endocrinology, and Metabolic Diseases, National Institute of Diabetes and Digestive and Kidney, National Institutes of Health, Bethesda, Maryland; and.
Beena
B
Akolkar
Division of Diabetes, Endocrinology, and Metabolic Diseases, National Institute of Diabetes and Digestive and Kidney, National Institutes of Health, Bethesda, Maryland; and.
Lisa M
LM
Spain
Information Management Services, Inc., Calverton, Maryland.
Michael H
MH
Guill
Information Management Services, Inc., Calverton, Maryland.
Corey T
CT
Del Vecchio
Information Management Services, Inc., Calverton, Maryland.
Leslie E
LE
Carroll
D022126:Access to Information; D035843:Biomedical Research / Q000379:methods*; D003299:Cooperative Behavior; D057225:Data Mining; D016208:Databases, Factual; D006801:Humans; D033181:Information Dissemination; D033183:Interdisciplinary Communication; D007391:International Cooperation; D054586:National Institute of Diabetes and Digestive and Kidney Diseases (U.S.); D009398:Nephrology / Q000379:methods*; D014481:United States
biosamples; chronic kidney disease; renal disease; repository