Blockade of endothelial cell protein C receptor augments factor VIIa hemostatic effect in hemophilia treatment.
Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX.
Jagan
J
Sundaram
Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX.
Usha R
UR
Pendurthi
Coagulation Biology Laboratory, Oklahoma Medical Research Foundation, Oklahoma City, OK.
Charles T
CT
Esmon
Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX.
L Vijaya Mohan
LV
Rao
D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects; D042783:Endothelial Cells / Q000187:drug effects* / Q000378:metabolism; D000074283:Endothelial Protein C Receptor; D015942:Factor VIIa / Q000378:metabolism / Q000494:pharmacology*; D006467:Hemophilia A / Q000188:drug therapy* / Q000378:metabolism; D008817:Mice, Mutant Strains; D011956:Receptors, Cell Surface / Q000037:antagonists & inhibitors* / Q000378:metabolism
D000074283:Endothelial Protein C Receptor; C080248:Procr protein, mouse; D011956:Receptors, Cell Surface; D015942:Factor VIIa