Synthesis of gem-difluorinated nitroso compounds.
A method for the synthesis of gem-difluorinated nitroso compounds is described. The reaction involves interaction of organozinc reagents with (bromodifluoromethyl)trimethylsilane followed by nitrosation of difluorinated organozinc species with an n-butyl nitrite/chlorotrimethylsilane system.
N. D. Zelinsky Institute of Organic Chemistry , 119991 Moscow, Leninsky prosp. 47, Russian Federation.
Vladimir O
VO
Smirnov
Marina I
MI
Struchkova
Dmitry E
DE
Arkhipov
Alexander A
AA
Korlyukov
Alexander D
AD
Dilman
D006845:Hydrocarbons, Fluorinated / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents / Q000737:chemistry*; D015394:Molecular Structure; D009573:Nitrites / Q000737:chemistry*; D015538:Nitrosation; D009603:Nitroso Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D014297:Trimethylsilyl Compounds / Q000737:chemistry*
C000599115:(bromodifluoromethyl)trimethylsilane; D006845:Hydrocarbons, Fluorinated; D007202:Indicators and Reagents; D009573:Nitrites; D009603:Nitroso Compounds; D014297:Trimethylsilyl Compounds; C024225:n-butyl nitrite; C039293:trimethylchlorosilane