Resistance of Aedes aegypti to temephos and adaptive disadvantages.
OBJECTIVE
To evaluate the resistance of Aedes aegypti to temephos Fersol 1G (temephos 1% w/w) associated with the adaptive disadvantage of insect populations in the absence of selection pressure.


METHODS
A diagnostic dose of 0.28 mg a.i./L and doses between 0.28 mg a.i./L and 1.40 mg a.i./L were used. Vector populations collected between 2007 and 2008 in the city of Campina Grande, state of Paraíba, were evaluated. To evaluate competition in the absence of selection pressure, insect populations with initial frequencies of 20.0%, 40.0%, 60.0%, and 80.0% resistant individuals were produced and subjected to the diagnostic dose for two months. Evaluation of the development of aquatic and adult stages allowed comparison of the life cycles in susceptible and resistant populations and construction of fertility life tables.


RESULTS
No mortality was observed in Ae. aegypti populations subjected to the diagnostic dose of 0.28 mg a.i./L. The decreased mortality observed in populations containing 20.0%, 40.0%, 60.0%, and 80.0% resistant insects indicates that temephos resistance is unstable in the absence of selection pressure. A comparison of the life cycles indicated differences in the duration and viability of the larval phase, but no differences were observed in embryo development, sex ratio, adult longevity, and number of eggs per female.


CONCLUSIONS
The fertility life table results indicated that some populations had reproductive disadvantages compared with the susceptible population in the absence of selection pressure, indicating the presence of a fitness cost in populations resistant to temephos.
Morgana Michele Cavalcanti de Souza Leal
MM
Diniz
Alleksandra Dias da Silva
AD
Henriques
Renata da Silva
Rda S
Leandro
Dalvanice Leal
DL
Aguiar
Eduardo Barbosa
EB
Beserra
D000330:Aedes / Q000254:growth & development; D000818:Animals; D001938:Brazil; D003715:Dengue / Q000517:prevention & control; D005260:Female; D007303:Insect Vectors / Q000254:growth & development; D007305:Insecticide Resistance; D008297:Male; D009032:Mosquito Control / Q000379:methods; D000002:Temefos
D000002:Temefos