Serous adenocarcinoma of the ovary diagnosed during ultrasound evaluation for fertility preservation.
Breast cancer is the most common malignant tumor in women of reproductive age, and fertility preservation counseling is now an integral part of the initial management of these patients. This article reports the case of a 33-year-old woman diagnosed with breast cancer and referred for oncofertility counseling before her treatment. Despite a previous negative cancer workup, a transvaginal ultrasound scan, performed for antral follicle count as part of the initial ovarian reserve assessment, revealed a synchronous ovarian adenocarcinoma. A BRCA1 mutation was confirmed weeks later. This report highlights the role of transvaginal ultrasound in the initial evaluation and reviews the risks associated with fertility preservation in breast cancer patients.
AP-HP, Service de Gynécologie-Obstétrique et Médecine de la Reproduction, Hôpital Antoine Béclère, Clamart, F-92141, France.
Hady El
HE
Hachem
Marine
M
Poulain
Marcos
M
Höher
Renato
R
Fanchin
René
R
Frydman
Michael
M
Grynberg
D000328:Adult; D001943:Breast Neoplasms / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000473:pathology; D018284:Cystadenocarcinoma, Serous / Q000000981:diagnostic imaging*; D005260:Female; D059247:Fertility Preservation; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging*; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging*; D014463:Ultrasonography
BRCA mutation; breast cancer; fertility preservation; oncofertility; transvaginal ultrasound