Proteus syndrome: a case report and a case study review in China.
Proteus syndrome (PS) is a rare and sporadic disorder characterized by overgrowth of multiple tissues and a propensity to develop particular neoplasms. The clinical manifestations of PS include macrodactyly, vertebral abnormalities, asymmetric limb overgrowth and length discrepancy, hyperostosis, abnormal and asymmetric fat distribution, asymmetric muscle development, connective tissue nevi, and vascular malformations. We report a 16-year old female patient who manifested a number of these complications and review the Chinese literature about the diagnosis, natural history, and management of PS.
Guangzhou Institute of Dermatology, Guangzhou, China;
Xi-Bao
XB
Zhang
Dongguan Institute of Dermatology, Dongguan, China.
Chang-Xing
CX
Li
Guangzhou Institute of Dermatology, Guangzhou, China;
Yu-Qing
YQ
He
Guangzhou Institute of Dermatology, Guangzhou, China;
San-Quan
SQ
Zhang
Guangzhou Institute of Dermatology, Guangzhou, China;
Yan-Xia
YX
Cai
Proteus syndrome; clinical manifestation; diagnosis