More than 9 years of continuous trastuzumab treatment in metastatic breast cancer without cardiac toxicity: a case report and literature review.
The main concern of long-term use of trastuzumab remains its association with potential cardiac side effects. Although these side effects are real, they are probably overemphasized. We report the case of a woman with metastatic breast cancer, who is currently in complete remission, and who received trastuzumab continuously for more than 9 years, without any significant cardiac toxicity.
Department of Oncology, Universitatea de Medicina si Farmacie, Craiova, Romania.
Florin
F
Badulescu
Department of Surgery, Universitatea Titu Maiorescu, Bucuresti, Romania.
Adriana
A
Badulescu
Monter Cancer Center, North Shore LIJ Cancer Institute, Lake Success, NY, USA.
Doru
D
Paul
Department of Pathology, Spitalul Universitar Clinic de Urgenta, Craiova, Romania.
Carmen Florina
CF
Popescu
Department of Cardiology, Universitatea de Medicina si Farmacie, Craiova, Romania.
Cristina
C
Florescu
long survival; metastatic breast cancer; trastuzumab