Grading and interpretation of white matter hyperintensities using statistical maps.
OBJECTIVE
We aimed to generate rigorous graphical and statistical reference data based on volumetric measurements for assessing the relative severity of white matter hyperintensities (WMHs) in patients with stroke.


METHODS
We prospectively mapped WMHs from 2699 patients with first-ever ischemic stroke (mean age=66.8±13.0 years) enrolled consecutively from 11 nationwide stroke centers, from patient (fluid-attenuated-inversion-recovery) MRIs onto a standard brain template set. Using multivariable analyses, we assessed the impact of major (age/hypertension) and minor risk factors on WMH variability.


RESULTS
We have produced a large reference data library showing the location and quantity of WMHs as topographical frequency-volume maps. This easy-to-use graphical reference data set allows the quantitative estimation of the severity of WMH as a percentile rank score. For all patients (median age=69 years), multivariable analysis showed that age, hypertension, atrial fibrillation, and left ventricular hypertrophy were independently associated with increasing WMH (0-9.4%, median=0.6%, of the measured brain volume). For younger (≤69) hypertensives (n=819), age and left ventricular hypertrophy were positively associated with WMH. For older (≥70) hypertensives (n=944), age and cholesterol had positive relationships with WMH, whereas diabetes mellitus, hyperlipidemia, and atrial fibrillation had negative relationships with WMH. For younger nonhypertensives (n=578), age and diabetes mellitus were positively related to WMH. For older nonhypertensives (n=328), only age was positively associated with WMH.


CONCLUSIONS
We have generated a novel graphical WMH grading (Kim statistical WMH scoring) system, correlated to risk factors and adjusted for age/hypertension. Further studies are required to confirm whether the combined data set allows grading of WMH burden in individual patients and a tailored patient-specific interpretation in ischemic stroke-related clinical practice.
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Wi-Sun
WS
Ryu
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Sung-Ho
SH
Woo
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Dawid
D
Schellingerhout
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Moo K
MK
Chung
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Chi Kyung
CK
Kim
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Min Uk
MU
Jang
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Kyoung-Jong
KJ
Park
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Keun-Sik
KS
Hong
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Sang-Wuk
SW
Jeong
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Jeong-Yong
JY
Na
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Ki-Hyun
KH
Cho
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Joon-Tae
JT
Kim
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Beom Joon
BJ
Kim
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Moon-Ku
MK
Han
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Jun
J
Lee
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Jae-Kwan
JK
Cha
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Dae-Hyun
DH
Kim
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Soo Joo
SJ
Lee
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Youngchai
Y
Ko
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Yong-Jin
YJ
Cho
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Byung-Chul
BC
Lee
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Kyung-Ho
KH
Yu
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Mi-Sun
MS
Oh
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Jong-Moo
JM
Park
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Kyusik
K
Kang
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Kyung Bok
KB
Lee
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Tai Hwan
TH
Park
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Juneyoung
J
Lee
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Heung-Kook
HK
Choi
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.).
Kiwon
K
Lee
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.). kdongeog@duih.org braindoc@snu.ac.kr.
Hee-Joon
HJ
Bae
From the Stroke Center and Korean Brain MRI Data Center, Dongguk University Ilsan Hospital, Goyang, Korea (W.-S.R., S.-H.W., S.-W.J., J.-Y.N., D.-E.K.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston (D.S.); Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison (M.K.C.); WeBace Co, Ltd, Busan, Korea (K.-J.P.); Department of Neurology, Seoul National University Hospital, Seoul, Korea (C.K.K.); Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea (M.U.J.); Department of Neurology, Ilsan Paik Hospital, Goyang, Korea (K.-S.H., Y.-J.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (K.-H.C., J.-T.K.); Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea (B.J.K., M.-K.H., H.-J.B.); Department of Neurology, Yeungnam University Hospital, Daegu, Korea (J.L.); Department of Neurology, Dong-A University Hospital, Busan, Korea (J.-K.C., D.-H.K.); Department of Neurology, Eulji University Hospital, Daejeon, Korea (S.J.L., Y.K.); Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L., K.-H.Y., M.-S.O.); Department of Neurology, Eulji General Hospital, Seoul, Korea (J.-M.P., K.K.); Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea (K.B.L.); Department of Neurology, Seoul Medical Center, Seoul, Korea (T.H.P.); Department of Biostatistics, Korea University College of Medicine, Seoul, Korea (J.L.); Department of Computer Science, Inje University, Busan, Korea (H.-K.C.); and Departments of Neurology and Neurosurgery, The University of Texas Health Science Center, Houston (K.L.). kdongeog@duih.org braindoc@snu.ac.kr.
Dong-Eog
DE
Kim
D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D020521:Stroke / Q000473:pathology*; D066127:White Matter / Q000473:pathology*
cerebral infarction; leukoaraiosis; magnetic resonance imaging; topographic brain mapping