Concurrent emphysematous pyelonephritis and thigh necrotizing fasciitis after intramuscular administration of diclofenac.
Necrotizing fasciitis (NF) is a rapidly progressive, life-threatening soft tissue infection. NF may result from any injury to the skin or from hematogenous spread. However, con-current emphysematous pyelonephritis and necrotizing fasciitis of the left thigh has not been reported. We report a case of emphysematous pyelonephritis and necrotizing fasciitis of the left thigh after intramuscular administration of diclofenac that improved with aggressive management including broad-spectrum antibiotics, nephrectomy and surgical intervention.
Department of Nephrology, Ziaeian Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Fateme Shamekhi
FS
Amiri
Alireza
A
Foroughi
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D004008:Diclofenac / Q000008:administration & dosage*; D004646:Emphysema / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D004927:Escherichia coli Infections / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D019115:Fasciitis, Necrotizing / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular / Q000009:adverse effects*; D009392:Nephrectomy; D011704:Pyelonephritis / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D013848:Thigh; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D004008:Diclofenac