Melatonin: a "Higgs boson" in human reproduction.
As the Higgs boson could be a key to unlocking mysteries regarding our Universe, melatonin, a somewhat mysterious substance secreted by the pineal gland primarily at night, might be a crucial factor in regulating numerous processes in human reproduction. Melatonin is a powerful antioxidant which has an essential role in controlling several physiological reactions, as well as biological rhythms throughout human reproductive life. Melatonin, which is referred to as a hormone, but also as an autocoid, a chronobiotic, a hypnotic, an immunomodulator and a biological modifier, plays a crucial part in establishing homeostatic, neurohumoral balance and circadian rhythm in the body through synergic actions with other hormones and neuropeptides. This paper aims to analyze the effects of melatonin on the reproductive function, as well as to shed light on immunological and oncostatic properties of one of the most powerful hormones.
Department of Obstetrics and Gynecology "Narodni front" .
Svetlana
S
Dragojevic Dikic
Ana Mitrovic
AM
Jovanovic
Srdjan
S
Dikic
Tomislav
T
Jovanovic
Aleksandar
A
Jurisic
Aleksandar
A
Dobrosavljevic
D002940:Circadian Rhythm / Q000502:physiology; D047108:Embryonic Development / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008550:Melatonin / Q000378:metabolism / Q000502:physiology*; D006080:Ovarian Follicle / Q000502:physiology; D010870:Pineal Gland / Q000502:physiology; D011247:Pregnancy; D011627:Puberty / Q000502:physiology; D012098:Reproduction / Q000502:physiology*
D008550:Melatonin
Cancer; immune function; melatonin; reproductive function; reproductive health