Retrospective comparison of 25-gauge vitrectomy for repair of proliferative vitreoretinopathy with or without anterior proliferation.
OBJECTIVE
The purpose of the study was to compare the outcomes of 25-gauge vitrectomy for the repair of rhegmatogenous retinal detachment (RRD) complicated by proliferative vitreoretinopathy (PVR) with and without anterior PVR (A-PVR).


METHODS
We reviewed the medical records of 26 eyes of 26 patients who underwent 25-gauge vitrectomy for grade C PVR with A-PVR and 16 eyes of 16 patients who underwent the same procedure for grade C PVR without A-PVR.


RESULTS
The number of previous surgeries for RRD was significantly higher in A-PVR cases than in those without A-PVR (P = 0.021). Scleral buckling and retinotomy/retinectomy were performed significantly more frequently in A-PVR eyes than in those without A-PVR (P = 0.017 and <0.001, respectively). The A-PVR eyes required longer surgical times than those without A-PVR (P =0.001). Final anatomical success was achieved in 24 of 26 (92.3 %) eyes with A-PVR and 16 of 16 (100 %) eyes without A-PVR (P =0.517). Best-corrected visual acuity before and six months after vitrectomy was 1.41 ± 0.96 and 0.86 ± 0.78 logarithm of minimal angle of resolution (logMAR) units, respectively, in eyes with A-PVR and 1.17 ± 0.87 and 0.63 ± 0.72 logMAR units, respectively, in eyes without A-PVR (P =0.355 and 0.276, respectively).


CONCLUSIONS
These results indicate that 25-gauge vitrectomy can be used for both types of PVR, although eyes with A-PVR may require scleral buckling and retinotomy/retinectomy more often and may require longer surgical times.
Osaka Rosai Hospital Clinical Research Center for Occupational Sensory Organ Disability, 1179-3 Nagasone-cho, Kita-ku, Sakai, 591-8025, Japan, tatsusatou@gmail.com.
Tatsuhiko
T
Sato
Kazuyuki
K
Emi
Hajime
H
Bando
Toshihide
T
Ikeda
D000293:Adolescent; D000328:Adult; D000368:Aged; D049109:Cell Proliferation; D058450:Endotamponade; D005260:Female; D005466:Fluorocarbons / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008866:Microsurgery; D008875:Middle Aged; D012163:Retinal Detachment / Q000150:complications / Q000601:surgery*; D012189:Retrospective Studies; D012591:Scleral Buckling; D012827:Silicone Oils / Q000008:administration & dosage; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy / Q000379:methods*; D018630:Vitreoretinopathy, Proliferative / Q000209:etiology / Q000601:surgery*
D005466:Fluorocarbons; D012827:Silicone Oils