High renal resistive index in hypertensive patients is also associated with serum homocysteine level.
BACKGROUND
Hypertension, homocysteine and renal resistive index are associated with atherosclerosis and lead to cardiovascular diseases. In this study, we aimed to investigate the association between homocysteine and renal resistive index in patients with newly diagnosed hypertension.


METHODS
A total of 221 subjects were included in this case-control study. The study group consisted of 116 hypertensive patients and the control group consisted of 105 healthy subjects. Renal resistive index, homocysteine levels, insulin concentrations and blood pressures were measured.


RESULTS
Renal resistive index, serum homocysteine levels and insulin concentrations were higher in hypertensive patients (p = 0.006, p < 0.001, respectively). Serum homocysteine levels were associated with hypertension (OR 9.5, Cl 95 % 4.86-18.7, p < 0.001). Homocysteine and insulin levels were positively correlated with renal resistive index (r = 0.372, p = 0.001; r = 0.392, p < 0.001, respectively).


CONCLUSIONS
High renal resistive index in hypertensive patients is associated with homocysteine.
Department of Internal Medicine, Numune Training and Research Hospital, Yüreğir, Adana, 01240, Turkey, drkeskek@yahoo.com.
Şakir Özgür
ŞÖ
Keşkek
Yavuz
Y
Çinar
Sinan
S
Kirim
Tayyibe
T
Saler
D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000000981:diagnostic imaging / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D014463:Ultrasonography; D014655:Vascular Resistance
D006710:Homocysteine