Clinical characteristics of cerebral venous thrombosis in a single center in Korea.
OBJECTIVE
The purpose of this study is to investigate the clinical characteristics of cerebral venous thrombosis (CVT) in a single center in Korea.


METHODS
A total of 36 patients were diagnosed with CVT from August 2005 to May 2013. The patient data regarding age, sex, disease stage, pathogenesis, location, laboratory findings, radiological findings, and treatment modalities were retrospectively collected. The results were compared with those of previous studies in other countries.


RESULTS
The patient group comprised 21 men and 15 women with a mean age of 46.9 years (ranging from three months to 77 years). The most common cause was a prothrombotic condition (8 patients, 22.2%). Within the patient group, 13 patients (36.1%) had a hemorrhagic infarction, whereas 23 (63.9%) had a venous infarction without hemorrhage. By location, the incidence of hemorrhagic infarction was the highest in the group with a transverse and/or sigmoid sinus thrombosis (n=9); however, the proportion of hemorrhagic infarction was higher in the cortical venous thrombosis group (75%) and the deep venous thrombosis group (100%). By pathogenesis, the incidence of hemorrhagic infarction was the highest in the prothrombotic group (n=6), which was statistically significant (p=0.016).


CONCLUSIONS
According to this study, CVT was more prevalent in men, and the peak age group comprised patients in the sixth decade. The most common cause was a prothrombotic condition. This finding was comparable with reports from Europe or America, in which CVT was more common in younger women. Hemorrhagic infarction was more common in the prothrombotic group (p=0.016) than in the non-prothrombotic group in this study.
Department of Neurosurgery, Konkuk University Medical Center, Seoul, Korea.
Dong Sun
DS
Park
Department of Neurosurgery, Konkuk University Medical Center, Seoul, Korea.
Chang Taek
CT
Moon
Department of Neurosurgery, Konkuk University Medical Center, Seoul, Korea.
Young Il
YI
Chun
Department of Neurosurgery, Konkuk University Medical Center, Seoul, Korea.
Young-Cho
YC
Koh
Department of Neurology, Konkuk University Medical Center, Seoul, Korea.
Hahn Young
HY
Kim
Department of Radiology, Konkuk University Medical Center, Seoul, Korea.
Hong Gee
HG
Roh
Cerebral venous thrombosis; Hemorrhagic infarction; Prothrombotic condition