Bilateral ocular manifestations of aggressive cutaneous metastatic melanoma.
OBJECTIVE
To report an unusual case of aggressive cutaneous malignant melanoma metastatic to both eyes. The case is also remarkable for differences from the bilateral diffuse uveal melanocytic proliferation syndrome (BDUMP).


METHODS
Observational case report.


METHODS
The authors studied the case of a 56-year-old man with decreased vision and floaters in the left eye. He recently had been diagnosed with metastatic cutaneous malignant melanoma.


RESULTS
Clinical examination, fundus photography, and ultrasonography revealed widespread metastases to the choroid, ciliary body, iris, and eyelid. A-scan revealed medium internal reflectivity of a collar-button lesion in the ciliary body, consistent with metastatic disease.


CONCLUSIONS
Despite the rarity of BDUMP and bilateral intraocular malignant cutaneous or uveal melanoma metastases, these diagnoses should be considered when diffuse bilateral melanocytic lesions are present. Ultrasonography and metastatic workup are critically important to help distinguish these disease entities.
From *Bascom Palmer Eye Institute, Department of Ophthalmology, †Department of Medicine, and ‡Department of Radiation Oncology, University of Miami Miller School of Medicine, Florida.
Colleen M
CM
Cebulla
Armando
A
Alegret
Lynn
L
Feun
Arnold M
AM
Markoe
Ditte J
DJ
Hess
Timothy G
TG
Murray