Retinoblastoma in oculocutaneous albinism.
OBJECTIVE
To report a case of retinoblastoma in a child with oculocutaneous albinism (OCA).


METHODS
A 24-month-old girl with classic features of OCA developed leukocoria in the left eye.


RESULTS
The patient was found to have an endophytic retinoblastoma and an exophytic retinoblastoma, with a total retinal detachment and neovascularization of the iris. Enucle-ation was performed, and histopathology confirmed massive retinoblastoma with optic nerve involvement to the posterior margin of the lamina cribrosa but no choroidal invasion.


CONCLUSIONS
Although rare, retinoblastoma can occur in children with OCA.
From the *Ocular Oncology Service and †Pathology Department, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania.
Fariba
F
Ghassemi
Carol L
CL
Shields
Cesare
C
Pirondini
Ralph C
RC
Eagle
Jerry A
JA
Shields