Secondary proliferations in heavy silicone oil endotamponade.
OBJECTIVE
To describe postoperative complications in a patient with a giant retinal tear and heavy silicone oil endotamponade.


METHODS
Case report.


RESULTS
A 16-year-old girl with a giant retinal tear underwent 20-gauge three-port pars plana vitrectomy with scleral buckling and heavy silicone oil endotamponade (Oxane HD; Bausch & Lomb, Toulouse, France). During follow-up, early emulsification of the silicone oil and severe secondary membrane proliferation within the silicone oil and retinal interface were detected. Exchange of silicone oil (5,000 centistokes) and membrane removal were performed. Histologic evaluation revealed fibrosis and a foreign body-type reaction.


CONCLUSIONS
Secondary proliferations may become a provoked inflammatory response to heavy silicone oil; therefore, further controlled clinical trials should be performed to evaluate these potential side effects before heavy silicone oil is routinely used as a temporary vitreous substitute in eyes with complicated retinal detachments.
From the Departments of *Ophthalmology and †Pathology, Dokuz Eylul University, Izmir, Turkey.
Suleyman
S
Kaynak
Hakan F
HF
Oner
Nilufer
N
Kocak
Banu
B
Lebe