Research progress in applying proteomics technology to explore early diagnosis biomarkers of breast cancer, lung cancer and ovarian cancer.
According to the China tumor registry 2013 annual report , breast cancer, lung cancer, and ovarian cancer are three common cancers in China nowadays, with high mortality due to the absence of early diagnosis technology. However, proteomics has been widespreadly implanted into every field of life science and medicine as an important part of post-genomics era research. The development of theory and technology in proteomics has provided new ideas and research fields for cancer research. Proteomics can be used not only for elucidating the mechanisms of carcinogenesis focussing on whole proteins of the tissue or cell, but also seeking the biomarkers for diagnosis and therapy of cancer. In this review, we introduce proteomics principles, covering current technology used in exploring early diagnosis biomarkers of breast cancer, lung cancer and ovarian cancer.
College of Veterinary Medicine, Sichuan Agricultural University, Yaan, Sichuan, China E-mail : yanqigui@126.com.
Lu
L
Luo
Li-You
LY
Dong
Qi-Gui
QG
Yan
San-Jie
SJ
Cao
Xin-Tian
XT
Wen
Yong
Y
Huang
Xiao-Bo
XB
Huang
Rui
R
Wu
Xiao-Ping
XP
Ma
D014408:Biomarkers, Tumor / Q000235:genetics*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000235:genetics; D002681:China; D055088:Early Detection of Cancer / Q000379:methods*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000235:genetics; D008297:Male; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000235:genetics; D040901:Proteomics / Q000379:methods*; D036301:Qualitative Research; D012042:Registries
D014408:Biomarkers, Tumor