The utility of dermoscopy in the diagnosis of evolving lesions of vitiligo.
BACKGROUND
Early lesions of vitiligo can be confused with various other causes of hypopigmentation and depigmentation. Few workers have utilized dermoscopy for the diagnosis of evolving lesions of vitiligo.


OBJECTIVE
To analyze the dermoscopic findings of evolving lesions in diagnosed cases of vitiligo and to correlate them histopathologically.


METHODS
Dermoscopy of evolving lesions in 30 diagnosed cases of vitiligo was performed using both polarized light and ultraviolet light.


RESULTS
On polarized light examination, the pigmentary network was found to be reduced in 12 (40%) of 30 patients, absent in 9 (30%), and reversed in 6 (20%) patients; 2 patients (6.7%) showed perifollicular hyperpigmentation and 1 (3.3%) had perilesional hyperpigmentation. A diffuse white glow was demonstrable in 27 (90%) of 30 patients on ultraviolet light examination. Melanocytes were either reduced in number or absent in 12 (40%) of 30 patients on histopathology.


CONCLUSIONS
Pigmentary network changes, and perifollicular and perilesional hyperpigmentation on polarized light examination, and a diffuse white glow on ultraviolet light examination were noted in evolving vitiligo lesions. Histopathological examination was comparatively less reliable. Dermoscopy appears to be better than routine histopathology in the diagnosis of evolving lesions of vitiligo and can obviate the need for a skin biopsy.
Department of Dermatology, Seth G.S Medical College and K.E.M Hospital, Parel, Mumbai, Maharashtra, India.
Sarvesh S
SS
Thatte
Uday S
US
Khopkar
D002452:Cell Count; D046169:Dermoscopy; D006801:Humans; D008544:Melanocytes; D010858:Pigmentation; D014466:Ultraviolet Rays; D014820:Vitiligo / Q000473:pathology*