Endoscopic sleeve gastroplasty for the treatment of obesity.
OBJECTIVE
Emerging endoscopic techniques are minimally invasive and can mimic the anatomic alterations achieved by surgical sleeve gastrectomy. The objective of this study was to evaluate endoscopic sleeve gastroplasty.


METHODS
This was a prospective, single-center study of 20 patients who underwent flexible endoscopic suturing for endoluminal gastric volume reduction. A multidisciplinary team provided postprocedure care. Patient status and weight were recorded at baseline, and at 1, 3, and 6 months after the procedure.


RESULTS
There were no adverse events and all patients were discharged in less than 24 hours. Baseline mean body mass index was 38.5 kg/m(2), and mean age was 45.8 years. Initial body weight (108.5 ± 14.9 kg) was significantly reduced. Following the procedure, the mean body weight reduction was 8.2 ± 2.5 kg at 1 month (% of initial weight loss 7.6 %; P < 0.05), 13.6 ± 4.8 kg at 3 months (12.4 % weight loss; P < 0.05), and 19.3 ± 8.9 kg at 6 months (17.8 % weight loss; P < 0.05).


CONCLUSIONS
Endoscopic sleeve gastroplasty can be effective for the treatment of patients with obesity.
Bariatric Endoscopy Unit, Madrid Sanchinarro University Hospital, Madrid, Spain.
Gontrand
G
Lopez-Nava
Gastro Obeso Center, Gastrointestinal Surgery, São Paulo, São Paulo, Brazil.
Manoel P
MP
Galvão
Bariatric Endoscopy Unit, Madrid Sanchinarro University Hospital, Madrid, Spain.
Immacula
I
da Bautista-Castaño
Bariatric Endoscopy Unit, Madrid Sanchinarro University Hospital, Madrid, Spain.
Amaya
A
Jimenez
Bariatric Endoscopy Unit, Madrid Sanchinarro University Hospital, Madrid, Spain.
Teresa
T
De Grado
Bariatric Endoscopy Unit, Madrid Sanchinarro University Hospital, Madrid, Spain.
Juan Pedro
JP
Fernandez-Corbelle
D000328:Adult; D015992:Body Mass Index; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D005260:Female; D015391:Gastroplasty / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000601:surgery*; D011446:Prospective Studies; D013536:Suture Techniques; D016896:Treatment Outcome; D015431:Weight Loss