Human papillomavirus-related verrucous carcinoma in a renal transplant patient after long-term immunosuppression: a case report.
BACKGROUND
Verrucous carcinoma is a slow-growing tumor with 3 main localizations: Oral cavity, ano-urogenital region, and plantar surface of the foot. On the sole it may rise adjacent to viral warts and very often is mistaken for the common verruca plantaris. Although both conditions-viral warts and cutaneous squamous cell carcinoma-are often diagnosed in immunosuppressed patients, in literature we have found only 3 case reports of verrucous carcinoma in organ transplant recipients.


METHODS
We present a case of 26-year-old man after deceased donor renal transplantation with plantar verrucous carcinoma successfully treated with excision and 5% imiquimod.
Department of Dermatology, Copernicus Podmiot Leczniczy sp z oo, Gdańsk; Polish College of Health, Beauty Care and Education in Poznań, Gdynia. Electronic address: bimko@wp.pl.
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Imko-Walczuk
Department of Nephrology, Transplantology and Internal Diseases, Medical University, Gdańsk.
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Cegielska
Department of Dermatology, Sexually Transmitted Diseases and Clinical Immunology, University of Varmia and Masuria, Olsztyn.
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Placek
Department of Dermatology, Sexually Transmitted Diseases and Immunodermatology, Collegium Medicum UMK, Bydgoszcz.
Sebastian
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Kaszewski
Department of General and Transplantation Surgery, Transplantation Institute, Warsaw, Poland.
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Fiedor
D000328:Adult; D052685:Alphapapillomavirus; D000634:Aminoquinolines / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000008:administration & dosage; D018289:Carcinoma, Verrucous / Q000473:pathology / Q000821:virology*; D005534:Foot Diseases / Q000473:pathology / Q000821:virology*; D006801:Humans; D000077271:Imiquimod; D016867:Immunocompromised Host; D007165:Immunosuppression Therapy / Q000009:adverse effects; D016030:Kidney Transplantation; D008297:Male; D030361:Papillomavirus Infections / Q000150:complications*; D012878:Skin Neoplasms / Q000473:pathology / Q000821:virology*
D000634:Aminoquinolines; D000970:Antineoplastic Agents; D000077271:Imiquimod