Synthesis, characterization, and biological evaluation of some new functionalized terphenyl derivatives.
New functionalized terphenyl derivatives incorporating various heterocyclic rings are prepared by using 4,4''-difluoro-5'-hydroxy-1,1':3',1''-terphenyl-4'-carbohydrazide as a key intermediate derived from 4,4'-difluoro chalcone, a versatile synthone. All the derivatives are characterized by (1)H NMR, IR, and mass spectral data. All the synthesized products are screened for their in vitro antimicrobial and antioxidant properties. The majority of the tested compounds exhibited significant antioxidant activity and some of them showed good antimicrobial activity.
Department of Studies in Chemistry, Mangalore University, Mangalagangotri, Karnataka, Mangalore 574 199, India.
Seranthimata
S
Samshuddin
Department of Studies in Chemistry, Mangalore University, Mangalagangotri, Karnataka, Mangalore 574 199, India.
Badiadka
B
Narayana
Research Department of Chemistry, P.A. College of Engineering, Nadupadavu, Karnataka, Mangalore 574153, India.
Balladka Kunhanna
BK
Sarojini
Department of Studies in Chemistry, Mangalore University, Mangalagangotri, Karnataka, Mangalore 574 199, India.
Divya N
DN
Shetty
Department of Biochemistry, K. S. Hegde Medical Academy, Deralakatte 574162, India.
Nalilu
N
Suchetha Kumari