Radiation maculopathy after epimacular brachytherapy for the treatment of subfoveal choroidal neovascularization secondary to age-related macular degeneration.
OBJECTIVE
To describe a case of radiation maculopathy after a 24-Gy single-fraction epimacular brachytherapy delivered concomitantly with ranibizumab for the treatment of age-related macular degeneration.


METHODS
Case report.


RESULTS
An 82-year-old man with neovascular age-related macular degeneration was treated with epiretinal brachytherapy and 2 intraocular injections of ranibizumab with initial good response. Nineteen months after initial treatment, visual acuity decreased and the patient was diagnosed of radiation maculopathy.


CONCLUSIONS
Radiation-related ocular side effects such as maculopathy may become evident several years after the treatment. Thus, vascular abnormalities that may appear in the follow-up of these patients can easily be misdiagnosed as a complication of the previous choroidal neovascularization.
From the *Instituto de Microcirugía Ocular, Retina Department, Barcelona, Spain; and †NeoVista, Inc, Fremont, California.
Rafael
R
Navarro
Anniken
A
Burés-Jelstrup
Luz M
LM
Vásquez
Carlos
C
Mateo
Jeffrey
J
Nau
Borja
B
Corcóstegui