Retinal vasculature remodeling in a case of systemic lupus erythematosus vaso-occlusive retinopathy.
OBJECTIVE
To report a case of systemic lupus erythematosus vaso-occlusive retinopathy illustrating vascular remodeling over 4 years of follow-up.


METHODS
Observational case report of one patient.


RESULTS
A 12-year-old previously healthy girl presented with profound vision loss to 20/800 in both eyes. Her medical workup, neuro-imaging, and ophthalmic examination were consistent with coexistent central nervous system systemic lupus erythematosus and vaso-occlusive systemic lupus erythematosus retinopathy. At 15 months after presentation, retinal vasculature remodeling was evident along with severe macular atrophy. By 4 years after presentation, retinal neovascularization developed that was successfully treated with photocoagulation.


CONCLUSIONS
We describe a case of systemic lupus erythematosus vaso-occlusive retinopathy illustrating vascular remodeling over 4 years of follow-up.
*Department of Ophthalmology, Doheny Eye Institute, University of Southern California, Los Angeles, California; and †Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York.
Rony
R
Gelman
Mary C
MC
Whitman
Jason
J
Horowitz
D002648:Child; D018450:Disease Progression; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D015356:Retinal Artery Occlusion / Q000209:etiology*; D012162:Retinal Degeneration / Q000209:etiology; D015861:Retinal Neovascularization / Q000209:etiology*