Coexistence of homologous-type cervical carcinosarcoma with endometrioid-type G1 endometrial cancer: a case report with an immunohistochemical study.
Coexistence of two or even more independent primary tumors derived from the female genital tract organs is a unique event. The most common combination is the coexistence of synchronous tumors in the ovary and endometrium. In the present case study, we described a coincidence of homologous-type cervical carcinosarcoma (CS) with endometrioid-type G1 uterine adenocarcinoma (EC) arising on the basis of hyperplastic endometrium. A panel of immunohistochemical markers was applied, either in both CS components or in endometrioid-type EC, to assess possible differences between both uterine malignancies. We also presented a short overview of the coexistence of cervical carcinosarcomas with other female genital tract malignancies.
IIND Department of Gynecology, Lublin Medical University Lublin, Poland.
Andrzej
A
Semczuk
Research Unit of Biomedicine and Translational Oncology, Vall d'Hebron University Hospital Barcelona, Spain.
Eva
E
Colas
Department of Clinical Pathology, Lublin Medical University Lublin, Poland.
Beata
B
Walczyna
Department of Gynecology, Bialystok Medical University Bialystok, Poland.
Maciej
M
Joźwik
Obstetrics and Gynecology Chair, Municipal Hospital Nowa Deba, Poland.
Andrzej
A
Pyra
Department of Obstetrics and Pathology of Pregnancy, Lublin Medical University Lublin, Poland.
Anna
A
Semczuk-Sikora
IIND Department of Gynecology, Lublin Medical University Lublin, Poland.
Tomasz
T
Rechberger
D014408:Biomarkers, Tumor / Q000032:analysis*; D001706:Biopsy; D018269:Carcinoma, Endometrioid / Q000737:chemistry* / Q000473:pathology / Q000628:therapy; D002296:Carcinosarcoma / Q000737:chemistry* / Q000473:pathology / Q000628:therapy; D003937:Diagnosis, Differential; D016889:Endometrial Neoplasms / Q000737:chemistry* / Q000473:pathology / Q000628:therapy; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D011237:Predictive Value of Tests; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000737:chemistry* / Q000473:pathology / Q000628:therapy
D014408:Biomarkers, Tumor
Cervical carcinosarcoma; endometrial cancer; endometrial hyperplasia; immunohistochemisty