Tear function in patients with chronic renal failure undergoing hemodialysis.
OBJECTIVE
To evaluate dry eye symptoms and clinical tear film alterations in patients with chronic renal failure (CRF).


METHODS
Thirty-five non-diabetic CRF patients undergoing hemodialysis, and 31 healthy individuals were enrolled. An ocular surface disease index questionnaire (OSDI) was administered, and after a complete ocular examination, Schirmer and tear break-up time (TBUT) tests were performed.


RESULTS
OSDI scores were significantly higher (p<0.01) and TBUT tests were significantly lower (p=0.01) in CRF patients than in the control group. Schirmer test results were also lower in the CRF patients group, but lacked statistical significance (p=0.20).


CONCLUSIONS
Patients with CRF should be advised to obtain an ophthalmic examination, especially for dry eye.
Department of Ophthalmology, Dumlupinar University School of Medicine , Kutahya , Turkey .
Serdar
S
Aktaş
Hacı Murat
HM
Sağdık
Hatice
H
Aktaş
Erim
E
Gülcan
Mehmet
M
Tetikoğlu
Süleyman
S
Coşgun
Sinan
S
Çalışkan
Fatih
F
Özcura
D000328:Adult; D000368:Aged; D002114:Calcinosis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000378:metabolism; D016022:Case-Control Studies; D003228:Conjunctiva / Q000378:metabolism / Q000473:pathology; D003941:Diagnostic Techniques, Ophthalmological; D015352:Dry Eye Syndromes / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000378:metabolism; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000453:epidemiology / Q000378:metabolism / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D006435:Renal Dialysis / Q000009:adverse effects* / Q000379:methods; D015203:Reproducibility of Results; D012307:Risk Factors; D011795:Surveys and Questionnaires; D013666:Tears / Q000378:metabolism*; D014421:Turkey / Q000453:epidemiology
Chronic renal failure; Schirmer test; dry eye; ocular surface disease index; tear break-up time