[Indication and technique of human fibrinogen/thrombin-coated collagen patch use in mucogingival surgery].
The aim of the study was to assess the effectiveness of fibrinogen/thrombin-coated collagen patch by mucogingival operations in patients with somatic diseases. Twenty-seven patients aged 25 to 45 (15 males and 12 females) with somatic diseases such as arterial hypertension (11 patients), diabetes (8 patients), bleeding disorders (8 patients) underwent Edlan-Mejcher vestibuloplasty. Using fibrinogen/thrombin-coated collagen patch as wound dressing caused marked hemostatic effect in 3 to 5 minutes even in hypertension and bleeding disorder patients. Wound heeling was observed 14 days post-op with no excessive scarring.
O A
OA
Zorina
A M
AM
Molchanov
R A
RA
Balykin
D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications; D005260:Female; D005340:Fibrinogen / Q000008:administration & dosage*; D005881:Gingiva / Q000601:surgery*; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000150:complications; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000601:surgery*; D019647:Oral Surgical Procedures; D062326:Re-Epithelialization; D013917:Thrombin / Q000008:administration & dosage*; D058106:Wound Closure Techniques
D005340:Fibrinogen; D013917:Thrombin