Spontaneous bilateral subhyaloid hemorrhage in congenital hypofibrinogenemia.
OBJECTIVE
The purpose of this study was to report a case of spontaneous bilateral subhyaloid hemorrhage in congenital hypofibrinogenemia.


METHODS
This is a single case report. A 14-year-old girl presented with a spontaneous bilateral decrease in vision. Her history was unremarkable. On examination, visual acuity was 20/80 in the right eye and 20/1200 in the left eye. Fundus examination showed bilateral subhyaloid hemorrhage. Clotting profile showed normal activated partial thromboplastin time and normal prothrombin time with fibrinogen decreased to 50 mg/dL (normal, 200-400 mg/dL).


RESULTS
Therapeutic cryoprecipitate infusion was administered. At 3 months, visual acuity improved to 20/20 with resolution of subhyaloid hemorrhage in both eyes.


CONCLUSIONS
Estimation of fibrinogen in the absence of other evaluated causes of blood dyscrasias would help with prompt diagnosis and successful management.
From the Department of Retina and Vitreous, L. V. Prasad Eye Institute, GMR Varalakshmi Campus, Vishakapatnam, Andhra Pradesh, India.
Avinash
A
Pathengay
Srinivas
S
Ambatipudi
Manohar
M
Mehta