Late reaction to ustekinumab infusion.
Psoriasis is a chronic inflammatory disease that directly affects the quality of life. Biologics are prescribed for patients unresponsive to conventional treatments and with severe forms of the disease. Ustekinumab is a fully human monoclonal antibody against the p40 subunit of interleukins 12/23 that is being used with satisfactory responses, achieving an improvement in the baseline Psoriasis Area and Severity Index of approximately 75% after 12 weeks of treatment. It has few side effects, including grater susceptibility to infections and development of reactions to the drug. Our report discusses a case of a cutaneous reaction to the use of ustekinumab in a 27 year-old male patient after the third dose of the medication. No similar case has been reported in the literature.
Irmandade Santa Casa de Misericórdia de Porto Alegre , Brazil.
Marina Resener
MR
Morais
Irmandade Santa Casa de Misericórdia de Porto Alegre , Brazil.
Luana Pizarro
LP
Meneghello
Irmandade Santa Casa de Misericórdia de Porto Alegre , Brazil.
Carina Flores
CF
de Oliveira
Irmandade Santa Casa de Misericórdia de Porto Alegre , Brazil.
André Vicente Esteves
AV
Carvalho
late adverse skin reactions; psoriasis; ustekinumab