Effects of hormones on platelet aggregation.
Platelets and their activation/inhibition mechanisms play a central role in haemostasis. It is well known agonists and antagonists of platelet activation; however, during the last years novel evidences of hormone effects on platelet activation have been reported. Platelet functionality may be modulated by the interaction between different hormones and their platelet receptors, contributing to sex differences in platelet function and even in platelet-mediated vascular damage. It has suggested aspects that apparently are well established should be reviewed. Hormones effects on platelet activity are included among them. This article tries to review knowledge about the involvement of hormones in platelet biology and activity.
Antonio López
AL
Farré
Javier
J
Modrego
José J
JJ
Zamorano-León
D002395:Catecholamines / Q000378:metabolism; D004967:Estrogens / Q000009:adverse effects; D005260:Female; D012739:Gonadal Steroid Hormones / Q000378:metabolism; D006728:Hormones / Q000378:metabolism*; D006801:Humans; D008297:Male; D015539:Platelet Activation / Q000187:drug effects / Q000502:physiology; D010974:Platelet Aggregation / Q000187:drug effects / Q000502:physiology*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D012737:Sex Factors
D002395:Catecholamines; D004967:Estrogens; D012739:Gonadal Steroid Hormones; D006728:Hormones; D010975:Platelet Aggregation Inhibitors