Epitheloid hemangioma treated with naproxen sodium.
Epitheloid hemangioma (EH) is a vascular tumor characterized by an epithelioid endothelial cell. Predominantly affecting the head and neck, fewer than 30 cases involving the scrotum have been published. As this represents an extremely rare entity, a multitude of anecdotal treatment modalities have been utilized including systemic/intralesional steroid therapy, radiotherapy, and chemical therapy. However, surgical excision remains the most widely accepted treatment option.We present a case of EH of the scrotum in a 14-year-old male patient that regressed after treatment with naproxen sodium. To the best of our knowledge, this represents the first reported case of scrotal EH regression following treatment with naproxen sodium.


METHODS
V.
From the *Department of Plastic Surgery, Institute of Dermatology and Plastic Surgery, Cleveland Clinic, Cleveland, OH; and †Department of Radiology, Akron Children Hospital, Akron, OH.
Elie
E
Nasr
Mary Roz
MR
Timbang
Lena
L
Naffaa
Gaby D
GD
Doumit
D000293:Adolescent; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005834:Genital Neoplasms, Male / Q000188:drug therapy*; D006391:Hemangioma / Q000188:drug therapy*; D006801:Humans; D060828:Induction Chemotherapy / Q000379:methods; D008297:Male; D009288:Naproxen / Q000627:therapeutic use*; D012611:Scrotum; D012878:Skin Neoplasms / Q000188:drug therapy*; D016896:Treatment Outcome
D000894:Anti-Inflammatory Agents, Non-Steroidal; D000970:Antineoplastic Agents; D009288:Naproxen