Posterior capsular opacification and Nd:YAG capsulotomy rates with the iMics Y-60H and Micro AY intra-ocular lenses: 3-year results of a randomized clinical trial.
OBJECTIVE
To compare the incidence and intensity of posterior capsular opacification (PCO) and neodymium:yttrium-aluminium-garnet (Nd:YAG) capsulotomy rates between two microincision intra-ocular lenses (IOLs) 3 years after surgery.


METHODS
Sixty-five patients randomly received a Y-60H IOL (HOYA Surgical Optics, Singapore) in one eye and a Micro AY IOL (PhysIOL, Liège, Belgium) in the contralateral eye during same-day bilateral cataract surgery. Eyes were examined 1 week, 20 months and 3 years after surgery. The amount of PCO (score: 0-10) was assessed subjectively at the slit lamp and objectively using automated image analysis software (aqua). Additionally, the Nd:YAG capsulotomy rate was noted.


RESULTS
Three years postoperatively, the objective PCO score of Y-60H IOLs was 1.9 ± 1.7 compared to PCO score of 1.7 ± 2.2 for the Micro AY IOLs (p = 0.66). Thirty-four percentage of the Y-60H eyes had undergone Nd:YAG capsulotomy, compared to 49% of the Micro AY eyes (p = 0.04). Significantly, more capsular folds were observed in the Y-60H IOL group (p = 0.001). There was no significant difference in best-corrected visual acuity, rhexis/IOL overlap and anterior capsule opacification 3 years after surgery.


CONCLUSIONS
Both microincision IOLs showed high YAG rates and comparable PCO scores 3 years after surgery. In the light of this unsatisfying PCO performance, the advantage of the present microincision IOLs over conventional IOLs must be questioned.
Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
Sabine M
SM
Schriefl
Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
Christina
C
Leydolt
Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
Eva
E
Stifter
Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
Rupert
R
Menapace
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D058442:Capsule Opacification / Q000453:epidemiology* / Q000601:surgery; D005260:Female; D006801:Humans; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular / Q000009:adverse effects*; D008297:Male; D008866:Microsurgery; D008875:Middle Aged; D018918:Phacoemulsification; D057852:Posterior Capsule of the Lens / Q000473:pathology; D064727:Posterior Capsulotomy / Q000706:statistics & numerical data*; D011446:Prospective Studies; D011474:Prosthesis Design; D014792:Visual Acuity / Q000502:physiology
Micro AY; Y-60H; hydrophilic acrylic; hydrophobic acrylic; microincision IOLs; posterior capsular opacification