Drug delivery and nanodetection in lung cancer.
Lung carcinoma is the most widespread type of cancer worldwide, and is responsible for more deaths than other types of cancer. Lung cancer remains the chief cause of cancer-related deaths in both men and women worldwide, and is increasingly common in women. Each year, the number of deaths from lung cancer is greater than the number due to breast and colorectal cancer combined. Lung cancer accounted for 13% (1.6 million) of the total cases and 18% (1.4 million) of the deaths in 2008. In Iran, lung cancer is one of the five leading tumors. Among females, it was the fourth most commonly diagnosed cancer, and the second leading cause of cancer death. Nanotechnology can be defined as the science and engineering involved in the design, characterization, and application of materials and devices whose smallest functional organization in at least one dimension is on the nanometer scale, i.e. one billionth of a meter. It is an exciting multidisciplinary field that involves the design and engineering of nano objects or nanotools with diameters less than 500 nanometers (nm), and it is one of the most interesting fields of the 21st century. Nanotechnology also offers the ability to detect diseases, such as tumors, much earlier than ever imaginable. This article presents nano devices for lung cancer detection and drug delivery systems.
b Department of Medical Biotechnology , Faculty of Advanced Medical Sciences, University of Medical Sciences , Tabriz , Iran.|c Student Research Committee, Tabriz University of Medical Sciences , Tabriz , Iran.
Fariba
F
Badrzadeh
b Department of Medical Biotechnology , Faculty of Advanced Medical Sciences, University of Medical Sciences , Tabriz , Iran.|e Department of Clinical Biochemistry , Faculty of Medicine, Tabriz University of Medical Sciences , Tabriz , Iran.
Mohammad
M
Rahmati-Yamchi
f Department of Laboratory Medicine , Islamic Azad University of Tabriz , Tabriz , Iran.
Kazem
K
Badrzadeh
d Department of Medical Nanotechnology , Faculty of Advanced Medical Sciences, University of Medical Sciences , Tabriz , Iran.
Alireza
A
Valizadeh
d Department of Medical Nanotechnology , Faculty of Advanced Medical Sciences, University of Medical Sciences , Tabriz , Iran.|e Department of Clinical Biochemistry , Faculty of Medicine, Tabriz University of Medical Sciences , Tabriz , Iran.
Nosratollah
N
Zarghami
d Department of Medical Nanotechnology , Faculty of Advanced Medical Sciences, University of Medical Sciences , Tabriz , Iran.
Samad Mussa
SM
Farkhani
a Drug Applied Research Center, Tabriz University of Medical Sciences , Tabriz , Iran.|d Department of Medical Nanotechnology , Faculty of Advanced Medical Sciences, University of Medical Sciences , Tabriz , Iran.
Abolfazl
A
Akbarzadeh
D000818:Animals; D004337:Drug Carriers / Q000737:chemistry; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000188:drug therapy*; D050997:Nanomedicine / Q000379:methods*
D004337:Drug Carriers
carbon nanotubes; drug delivery; liposomes; lung cancer; nanomaterials; nanomedicine; quantum dots