Low Tidal Volume Ventilation in Patients Without Acute Lung Injury.
Acute respiratory distress syndrome is a life threatening respiratory condition characterized by breakdown of the alveolar-capillary barrier, leading to flooding of the alveolar space producing the classical chest radiograph of bilateral pulmonary infiltrates. In this study, we employed lung protective ventilation strategies in patients without acute lung injury (ALI) to determine whether mechanical ventilation with lower tidal volume would provide more clinical benefits to patients without ALI.
Department of Intensive Care, the 208th Hospital of PLA, 4799 Xian Road, Changchun, 130062, China.
Weibing
W
Tang
Department of Intensive Care, the 208th Hospital of PLA, 4799 Xian Road, Changchun, 130062, China. drwangzhi2013@163.com.
Zhi
Z
Wang
Department of Intensive Care, the 208th Hospital of PLA, 4799 Xian Road, Changchun, 130062, China.
Ye
Y
Liu
Department of Intensive Care, the 208th Hospital of PLA, 4799 Xian Road, Changchun, 130062, China.
Jing
J
Zhu
D055371:Acute Lung Injury; D001992:Bronchoalveolar Lavage Fluid; D002196:Capillaries; D016207:Cytokines / Q000378:metabolism; D005260:Female; D006801:Humans; D053583:Interleukin-1beta / Q000378:metabolism; D015850:Interleukin-6 / Q000097:blood / Q000378:metabolism; D008168:Lung / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010343:Patient Admission; D011650:Pulmonary Alveoli / Q000473:pathology; D012121:Respiration, Artificial; D012128:Respiratory Distress Syndrome / Q000503:physiopathology*; D013990:Tidal Volume; D013997:Time Factors; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
D016207:Cytokines; C508585:IL1B protein, human; C508600:IL6 protein, human; D053583:Interleukin-1beta; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha
ARDS; Acute lung injury; Low tidal volume ventilation