Role of the different sexuality domains on the sexual function of women with premature ovarian failure.
BACKGROUND
Women with premature ovarian failure (POF) often manifest complaints involving different aspects of sexual function (SF), regardless of using hormone therapy. SF involves a complex interaction between physical, psychological, and sociocultural aspects. There are doubts about the impact of different complaints on the global context of SF of women with POF.


OBJECTIVE
To evaluate the percentage of influence of each of the sexuality domains on the SF in women with POF.


METHODS
Cross-sectional study with 80 women with POF, matched by age to 80 women with normal gonadal function. We evaluated SF through the "Female Sexual Function Index" (FSFI), a comparison between the POF and control groups using the Mann-Whitney test. Component exploratory factor analysis was used to assess the proportional influence of each domain on the composition of the overall SF for women in the POF group.


METHODS
SF was evaluated using FSFI. Exploratory Factor Analysis for components was used to evaluate the role of each domain on the SF of women with POF.


RESULTS
The FSFI score was significantly worse for women with POF, with a decrease in arousal, lubrication, orgasm, satisfaction, and dyspareunia. Exploratory factor analysis of SF showed that the domain with greater influence in the SF was arousal, followed by desire, together accounting for 41% of the FSFI. The domains with less influence were dyspareunia and lubrication, which together accounted for 25% of the FSFI.


CONCLUSIONS
Women with POF have impaired SF, determined mainly by changes in arousal and desire. Aspects related to lubrication and dyspareunia complaints have lower determination coefficient in SF. These results are important in adapting the approach of sexual disorders in this group of women.
Department of Obstetrics and Gynecology, School of Medicine, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
Cristina Laguna
CL
Benetti-Pinto
Patrícia Magda
PM
Soares
Helena Patrícia Donovan
HP
Giraldo
Daniela Angerame
DA
Yela
D000328:Adult; D001143:Arousal; D003075:Coitus / Q000523:psychology*; D003430:Cross-Sectional Studies; D004414:Dyspareunia / Q000503:physiopathology* / Q000523:psychology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009948:Orgasm; D010549:Personal Satisfaction; D016649:Primary Ovarian Insufficiency / Q000503:physiopathology* / Q000523:psychology*; D012725:Sexual Behavior / Q000523:psychology*; D019529:Sexuality; D011795:Surveys and Questionnaires; D016387:Women's Health
Dyspareunia; Female Sexual Function; Premature Ovarian Failure; Sexual Dysfunction; Sexuality