Inverted Linear Halbach Array for Separation of Magnetic Nanoparticles.
A linear array of Nd-Fe-B magnets has been designed and constructed in an inverted Halbach configuration for use in separating magnetic nanoparticles. The array provides a large region of relatively low magnetic field, yet high magnetic field gradient in agreement with finite element modeling calculations. The magnet assembly has been combined with a flow channel for magnetic nanoparticle suspensions, such that for an appropriate distance away from the assembly, nanoparticles of higher moment aggregate and accumulate against the channel wall, with lower moment nanoparticles flowing unaffected. The device is demonstrated for iron oxide nanoparticles with diameters of ~ 5 and 20 nm. In comparison to other approaches, the inverted Halbach array is more amenable to modeling and to scaling up to preparative quantities of particles.
Department of Physics and Astronomy, Oberlin College, Oberlin, OH 44074 USA.
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Y
Ijiri
Department of Physics and Astronomy, Oberlin College, Oberlin, OH 44074 USA.
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C
Poudel
Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195 USA ; Cambrian Technologies, Inc., Cleveland, OH 44109 USA.
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Williams
Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195 USA.
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Moore
Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195 USA.
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Orita
Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195 USA.
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Zborowski
magnetic liquids; magnetic separation; nanoparticles; permanent magnets