mimicMe: a web server for prediction and analysis of host-like proteins in microbial pathogens.
CONCLUSIONS
mimicMe is a web server for prediction and analysis of host-like proteins (mimics) encoded by microbial pathogens. Users select a host species and any set of pathogen and control proteomes (bacterial, fungal, protozoan or viral) and mimicMe reports host-like proteins that are unique to or enriched among pathogens. Additional server features include visualization of structural similarities between pathogen and host proteins as well as function-enrichment analysis.


METHODS
mimicMe is available at http://mimicme.uwaterloo.ca


BACKGROUND
acdoxey@uwaterloo.ca.
Department of Biology, University of Waterloo, Waterloo, Ontario, Canada.
Pavel
P
Petrenko
Department of Biology, University of Waterloo, Waterloo, Ontario, Canada.
Andrew C
AC
Doxey
D000595:Amino Acid Sequence; D001419:Bacteria / Q000235:genetics* / Q000378:metabolism / Q000472:pathogenicity; D001424:Bacterial Infections / Q000235:genetics / Q000378:metabolism / Q000382:microbiology*; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D054884:Host-Pathogen Interactions; D006801:Humans; D018716:Molecular Mimicry / Q000235:genetics*; D008969:Molecular Sequence Data; D020543:Proteome / Q000032:analysis; D017386:Sequence Homology, Amino Acid; D012984:Software; D037521:Virulence Factors / Q000235:genetics* / Q000378:metabolism
D001426:Bacterial Proteins; D020543:Proteome; D037521:Virulence Factors