Muscle glycogen metabolism changes in rats fed early postnatal a fructose-rich diet after maternal protein malnutrition: effects of acute physical exercise at the maximal lactate steady-state intensity.
BACKGROUND
The objective was to evaluate the muscle glucose metabolism in rats fed a fructose-rich diet after fetal protein malnutrition, at rest and after acute physical exercise at maximal lactate steady-state intensity.


METHODS
The male offspring born of mothers fed on a balanced or low-protein diet were split in four groups until 60 days: Balanced (B): balanced diet during the whole period; Balanced/Fructose (BF): balanced diet in utero and fructose-rich diet after birth; Low protein/Balanced (LB): low-protein diet in utero and balanced diet after birth; Low protein/Fructose (LF): low protein diet in utero and fructose-rich diet after birth.


RESULTS
Acute physical exercise reduced the muscle glycogen concentrations in all groups, although the LF group showed higher concentrations at rest. There was no difference among the groups in the glucose uptake and oxidation rates in the isolated soleus muscle neither at rest nor after acute exercise. However, glycogen synthesis was higher in the LF muscle than in the others at rest. Acute physical exercise increased glycogen synthesis in all groups, and the LF group showed the highest values.


CONCLUSIONS
The fructose-rich diet administered in rats after fetal protein malnutrition alters muscle glycogen concentrations and glycogen synthesis in the rest and after acute exercise at maximal lactate steady-state intensity.
São Paulo State University (UNESP), Rio Claro, SP Brazil ; Federal University of Mato Grosso (UFMT), Cuiabá, MT, Brazil. Physical Education Department, UFMT, Av. Fernando Corrêa da Costa, 2367 - Boa Esperança, Cuiabá, Zip-Code:- 78060-900 MT Brazil.
Lucieli T
LT
Cambri
São Paulo State University (UNESP), Rio Claro, SP Brazil.
Carla
C
Ribeiro
São Paulo State University (UNESP), Rio Claro, SP Brazil.
José D
JD
Botezelli
São Paulo State University (UNESP), Rio Claro, SP Brazil.
Ana C
AC
Ghezzi
São Paulo State University (UNESP), Rio Claro, SP Brazil.
Maria Ar
MA
Mello