Hemorrhagic recurrence of neovascular age-related macular degeneration not predicted by spectral domain optical coherence tomography.
OBJECTIVE
To report a case in which a patient with neovascular age-related macular degeneration developed a large submacular hemorrhage 2 days after spectral domain optical coherence tomography imaging, which revealed no intra- or subretinal fluid.


METHODS
A noninterventional case report.


RESULTS
A 93-year-old woman with neovascular age-related macular degeneration was seen for a regular follow-up examination 3 years after treatment with verteporfin photodynamic therapy in which lesion quiescence was achieved. Visual acuity was stable at 20/200, and spectral domain optical coherence tomography scans using 2 different instruments revealed no intra- or subretinal fluid. Two days after clinical examination and imaging, the patient presented with a large submacular hemorrhage and 5/400 vision.


CONCLUSIONS
Hemorrhagic exudation from choroidal neovascularization in age-related macular degeneration may occur suddenly, even in the absence of fluid detected by spectral domain optical coherence tomography.
From the Vitreous Retina Macula Consultants of New York, New York, New York.
Ron
R
Margolis
K Bailey
KB
Freund