Warthin's Tumour: A Case Report and Review on Pathogenesis and its Histological Subtypes.
Warthin's tumour/ Papillary cystadenoma lymphomatosum (PCL) constitutes a minority of salivary gland neoplasms and it is a monomorphic adenoma which primarily involves the parotid gland. Warthin's tumour shows multiple cysts that have numerous papillations covered by bilayered columnar and basaloid oncocytic epithelium. The connective tissue portion shows proliferation of follicle- containing lymphoid tissue which necessitates careful distinction for diagnosis. Although, Warthin's tumour presents as a clinically benign, slow-growing, usually asymptomatic lesion with low rates of recurrences and malignant transformation, but still this tumour is considered unique because of its histological appearance and unknown origin and pathogenesis. Here, we report a case of Warthin's tumour of five years duration in a 50-year-old male patient in the right parotid gland and also review and discuss various concepts concerning the development of this tumour along with a comprehensive literature on its clinic-pathologic features.
Professor, Department of Oral Pathology & Microbiology, Manipal College of Dental Sciences , Manipal, Karnataka, India .
Raghu
R
A R
Reader, Department of Oral Pathology & Microbiology, Sudha Rustagi College of Dental Sciences and Research Institute , Faridabad, Haryana, India .
Shweta
S
Rehani
Reader, Department of Oral Pathology & Microbiology, Jodhpur Dental College , Jodhpur, Rajasthan, India .
Kundendu Arya
KA
Bishen
Senior Lecturer, Department of Oral Pathology & Microbiology, Jodhpur Dental College , Jodhpur, Rajasthan, India .
Shitalkumar
S
Sagari
Development; Histogenesis; Warthin’s tumor