Role of the Wada test and functional magnetic resonance imaging in preoperative mapping of language and memory: two atypical cases.
The Wada test is an invasive procedure used to determine cerebral memory and language dominance as well as risk of cognitive deficits following neurosurgery. However, the potential risks of Wada testing have led some to consider foregoing Wada testing in candidates for resective epilepsy surgery with right hemispheric seizure onset. We present two atypical cases in which the Wada test showed unexpected memory and language lateralization. These cases underscore the importance of functional magnetic resonance in which imaging and Wada examination in right-handed individuals even when the lesion would not suggest atypical language representation.
a Department of Psychiatry and Biobehavioral Sciences , University of California , Los Angeles , CA , USA.
Monika M
MM
Połczyńska
Christopher F A
CF
Benjamin
Brian D
BD
Moseley
Patricia
P
Walshaw
Dawn
D
Eliashiv
Celia
C
Vigil
Michael
M
Jones
Susan Y
SY
Bookheimer
D000328:Adult; D001921:Brain / Q000503:physiopathology / Q000601:surgery; D001931:Brain Mapping / Q000379:methods*; D004292:Dominance, Cerebral; D004827:Epilepsy / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D007802:Language; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008568:Memory / Q000502:physiology*
Wada; epilepsy; fMRI; language; memory