Epithelial ovarian cancer - more data, more questions?
This review provides an overview of latest insights in epithelial ovarian cancer biology. The current understanding of the origin and the complex heterogeneity are depicted, followed by an introduction to the latest therapeutic approaches. The role of the tumor microenvironment, the high potential to disseminate within the peritoneal cavity, and new molecular biological findings are summarized.
Department of Obstetrics and Gynecology, Molecular Oncology Group, Comprehensive Cancer Center, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria, Stefanie.aust@meduniwien.ac.at.
Stefanie
S
Aust
Dietmar
D
Pils
D000970:Antineoplastic Agents / Q000627:therapeutic use; D002277:Carcinoma / Q000503:physiopathology* / Q000556:secondary / Q000628:therapy; D003131:Combined Modality Therapy; D018450:Disease Progression; D005260:Female; D006801:Humans; D058990:Molecular Targeted Therapy; D010051:Ovarian Neoplasms / Q000503:physiopathology* / Q000628:therapy; D010052:Ovariectomy; D010166:Palliative Care; D010534:Peritoneal Neoplasms / Q000503:physiopathology / Q000556:secondary / Q000628:therapy; D011379:Prognosis; D059016:Tumor Microenvironment / Q000502:physiology
D000970:Antineoplastic Agents