Bilateral diffuse uveal melanocytic proliferation and loss of retinal pigment epithelium.
OBJECTIVE
To describe a fundus autofluorescent photographic pattern in a case of bilateral diffuse uveal melanocytic proliferation (BDUMP) with occult esophageal carcinoma.


METHODS
Observational case report.


RESULTS
Color photography captured multiple round areas of discoloration throughout the fundus in a background of orange pigmentation that may have represented a lipofuscin-laden retinal pigment epithelium (RPE). Autofluorescence photography showed extensive nummular areas of hypoautofluorescence interspersed between areas of hyperautofluorescence as a result of extensive deposition of lipofuscin within the RPE.


CONCLUSIONS
Our case attests to the utility of autofluorescence photography as a sensitive, noninvasive imaging modality for the early detection of BDUMP.
From the *Department of Ophthalmology, Manhattan Eye, Ear & Throat Hospital and New York University School of Medicine, New York, New York; †Vitreous-Retina-Macula Consultants of New York, New York, New York; ‡State University of New York Downstate Medical Center, Brooklyn, New York; and §Wills Eye Hospital, Philadelphia, Pennsylvania.
Shantan
S
Reddy
Jay
J
Klancnik
Marcus S
MS
Edelstein
Brian
B
Marr
Michael J
MJ
Cooney