Uncovering the origins of a niche.
Multiple cell types that share a common origin cooperate to form a supportive niche for stem cells that give rise to blood and to the cells of the immune system.
Jeff M Bernitz is in the Department of Developmental and Regenerative Biology, Black Family Stem Cell Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, United States.
Jeff M
JM
Bernitz
Kateri A Moore is in the Department of Developmental and Regenerative Biology, Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, United States kateri.moore@mssm.edu.
Kateri A
KA
Moore
D000818:Animals; D004622:Embryo, Mammalian / Q000166:cytology; D047108:Embryonic Development; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000166:cytology; D051379:Mice; D008954:Models, Biological; D064231:Nestin / Q000378:metabolism; D055153:Stem Cell Niche
D064231:Nestin
bone marrow; developmental biology; hematopoietic stem cells; mesenchymal stem cells; mouse; neural crest; stem cell niche; stem cells