American tegumentary leishmaniasis - a case of therapeutic challenge.
American Tegumentary Leishmaniasis (ATL) is a chronic, non-contagious, infectious disease affecting millions of people worldwide. The timely and proper treatment is of great importance to prevent the disease from progressing to destructive and severe forms. Treatment for ATL recommended by the Brazilian Ministry of Health is similar for the whole country, regardless of the species of Leishmania. It is known that the response to treatment may vary with the strain of the parasite, the immune status of the patient and clinical form. We report the case of a healthy patient, coming from Manaus, Amazonas state, Brazil, who presented resistance to treatment with N-methyl-glutamine and liposomal amphotericin B, only being healed after using pentamidine.
Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil.
Daíne Vargas
DV
Couto
Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil.
Gunter
G
Hans Filho
Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil.
Marcelo Zanolli
MZ
Medeiros
Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil.
Carolina Faria Santos
CF
Vicari
Hospital São Julião, Campo Grande, MS, Brazil.
Aline Blanco
AB
Barbosa
Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil.
Luiz Carlos
LC
Takita
D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D001938:Brazil; D002648:Child; D004351:Drug Resistance; D005260:Female; D006801:Humans; D016773:Leishmaniasis, Cutaneous / Q000188:drug therapy* / Q000473:pathology; D010419:Pentamidine / Q000627:therapeutic use*; D016896:Treatment Outcome
D000981:Antiprotozoal Agents; D010419:Pentamidine