The challenge of methicillin resistant staphylococcal infection after total hip replacement: overlooked or overstated?
Advances in the treatment of periprosthetic joint infections of the hip have once more pushed prosthesis preserving techniques into the limelight. At the same time, the common infecting organisms are evolving to become more resistant to conventional antimicrobial agents. Whilst the epidemiology of resistant staphylococci is changing, a number of recent reports have advocated the use of irrigation and debridement and one-stage revision for the treatment of periprosthetic joint infections due to resistant organisms. This review presents the available evidence for the treatment of periprosthetic joint infections of the hip, concentrating in particular on methicillin resistant staphylococci.
University of British Columbia, Department of Orthopaedics, 3114-910 West 10th Avenue, Vancouver, British Columbia, Canada.
M C
MC
Parry
University of British Columbia, Department of Orthopaedics, 3114-910 West 10th Avenue, Vancouver, British Columbia, Canada.
C P
CP
Duncan
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D014943:Global Health; D006801:Humans; D015994:Incidence; D016106:Methicillin Resistance; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification*; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology
D000900:Anti-Bacterial Agents
Hip; MRSA; Periprosthetic Joint Infection; Two-stage revision