Septo-optic dysplasia associated with congenital persistent fetal vasculature, retinal detachment, and gastroschisis.
OBJECTIVE
The purpose of this study was to report the association of septo-optic dysplasia, persistent fetal vasculature, retinal detachment, and gastroschisis in a preterm neonate.


METHODS
This is a case report.


RESULTS
A female preterm neonate was found to have septo-optic dysplasia, with optic nerve hypoplasia, tripartite splitting of the vessels at the optic nerve, an ectopic pituitary gland, and absence of the septum pellucidum associated with persistent fetal vasculature, a retinal detachment, and gastroschisis.


CONCLUSIONS
Septo-optic dysplasia may also be associated with other ophthalmic findings and other developmental malformations as the authors report in this case. Follow-up should consist of a multidisciplinary approach with radiologic and endocrinology consultation.
*University of North Dakota, Grand Forks, North Dakota; and †Department of Ophthalmology, University of Minnesota, Minneapolis, Minnesota.
Michael A
MA
Jordan
Sandra R
SR
Montezuma
D000015:Abnormalities, Multiple; D000328:Adult; D006348:Cardiac Surgical Procedures / Q000379:methods; D004452:Echocardiography; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D020139:Gastroschisis / Q000175:diagnosis*; D006801:Humans; D007231:Infant, Newborn; D009900:Optic Nerve / Q000002:abnormalities*; D010547:Persistent Fetal Circulation Syndrome / Q000175:diagnosis* / Q000601:surgery; D012164:Retinal Diseases / Q000151:congenital* / Q000175:diagnosis; D025962:Septo-Optic Dysplasia / Q000175:diagnosis*; D012688:Septum Pellucidum / Q000002:abnormalities*