[Recent progress in research on oxidative stress in glaucoma].
Apoptosis of retinal ganglion cells and progressive loss of the axons is an important feature of glaucoma, its pathogenesis is not exact. Some experimental and clinical study found that oxidative stress plays an important role in the onset and progression of glaucoma. Oxidative stress markers were found in glaucoma patient's serum and ocular tissue and anti-oxidative stress therapy also had a role in controlling glaucoma. In this review, we will discuss the oxidative stress pathogenesis and the antioxidant therapy in glaucoma.
Department of Ophthalmology , General Hospital of Chinese People's Armed Police Forces, Beijing 100039, China.
Xibin
X
Zhou
Department of Ophthalmology , General Hospital of Chinese People's Armed Police Forces, Beijing 100039, China.
Rui
R
Liu
Department of Ophthalmology , General Hospital of Chinese People's Armed Police Forces, Beijing 100039, China. Email: fswuzhihong@sina.com.
Zhihong
Z
Wu
D000975:Antioxidants / Q000627:therapeutic use*; D017209:Apoptosis; D001369:Axons; D035843:Biomedical Research / Q000639:trends*; D005901:Glaucoma / Q000209:etiology* / Q000378:metabolism / Q000628:therapy*; D006801:Humans; D018384:Oxidative Stress; D012165:Retinal Ganglion Cells
D000975:Antioxidants