[Detection of bilirubin, CCR1, troponin I and IL-6 in patients with acute myocardial infarction].
OBJECTIVE
To detect the levels of plasma C-C chemokine receptor type 1 (CCR1), serum total bilirubin (TBIL), troponin I and interleukin-6 (IL-6) in acute myocardial infarction (AMI) patients.


METHODS
AMI group and control group respectively contained 65 samples. Diazo was used to detect the levels of serum TBIL, direct bilirubin (DBIL) and indirect bilirubin (IBIL). ELISA was used to detect the level of CCR1. Troponin I and IL-6 were detected by chemiluminescence analysis and radioimmunoassay, respectively.


RESULTS
The levels of TBIL [(15.07±2.87) μmol/L] and IBIL [(9.32±4.58) μmol/L] were significantly lower in AMI group than in control group [TBIL (20.15±3.26) μmol/L, IBIL (14.48±3.90) μmol/L] (P<0.05). However, the levels of CCR1, troponin I and IL-6 [(3.76± 0.85) ng/mL, (15.88±2.43) U/mL, (207.60± 23.94) U/mL] in AMI group were significantly higher than those in control group [CCR1 (0.66±0.19) ng/mL, troponin I (0.33±0.07) U/mL, IL-6 (103.55±16.86) U/mL] (P<0.05).


CONCLUSIONS
The levels of CCR1, troponin I and IL-6 were increased and the level of serum bilirubin was decreased in AMI patients.
Department of Emergency, Xuzhou Hospital of Traditional Chinese Medicine, Xuzhou 221000, China.
Bangguo
B
Kang
Department of Emergency, Xuzhou Hospital of Traditional Chinese Medicine, Xuzhou 221000, China.
Yuzhong
Y
Mao
D001663:Bilirubin / Q000097:blood*; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood*; D054389:Receptors, CCR1 / Q000097:blood*; D019210:Troponin I / Q000097:blood*
C515300:CCR1 protein, human; C508600:IL6 protein, human; D015850:Interleukin-6; D054389:Receptors, CCR1; D019210:Troponin I; D001663:Bilirubin