Resolution of a giant pigment epithelial detachment after treatment with intravitreal bevacizumab.
OBJECTIVE
To describe a patient with a giant pigment epithelial detachment (PED) successfully treated with intravitreal bevacizumab.


METHODS
Retrospective, observational case report.


METHODS
The patient's records were reviewed.


RESULTS
An 81-year-old man with history of age-related macular degeneration was seen on routine follow-up examination with an asymptomatic PED temporal to the macula in the right eye and visual acuity of 20/40. The patient was observed. Ten months later, the patient was found to have decreased vision to 20/80 and massive enlargement of the PED, with extension from the temporal equator into the macula. Optical coherence tomography of the macula showed a PED with overlying intraretinal cysts. The patient was given injections of intravitreal bevacizumab for every 4 months (1.25 mg) with complete resolution of the PED and return to baseline visual acuity of 20/40.


CONCLUSIONS
Giant PED secondary to exudative age-related macular degeneration can be successfully treated with intravitreal bevacizumab.
From the Retina Research Fund of St. Mary's Medical Center, San Francisco, and the Pacific Vision Foundation, California Pacific Medical Center, San Francisco, California.
Jon D
JD
Wender
Robert N
RN
Johnson
Richard H
RH
Roe
Alex T
AT
Bui
Emmett T
ET
Cunningham
Arthur D
AD
Fu
J Michael
JM
Jumper
H Richard
HR
McDonald