Nonfamilial vitreous amyloidosis diagnosed by portable sutureless vitrectomy.
OBJECTIVE
To describe a case of primary nonfamilial vitreous amyloidosis and a novel technique for expediting vitreous biopsy.


METHODS
Interventional case report.


METHODS
A 43-year-old man presented with progressive deterioration of vision and was found to have bilateral vitreous opacities. A systemic medical workup including family history was noncontributory. Given a high clinical suspicion of vitreous amyloidosis, the decision was made to obtain a vitreous biopsy for ultrastructural study. An office-based pars plana sutureless vitrectomy was performed. Pathologic study of the vitreous specimen confirmed the diagnosis of amyloidosis.


CONCLUSIONS
Vitreous amyloid deposition may occur with neither systemic involvement nor family history. Sutureless pars plana vitrectomy may facilitate diagnosis while saving time and expense for both the physician and the patient.
From the Department of Ophthalmology, Vitreoretinal Service, New York Medical College, Valhalla, New York.
Salil
S
Shukla
Amir
A
Cohen
Robert G
RG
Josephberg