Seven-year predictors of self-rated health and life satisfaction in the elderly: the PROOF study.
OBJECTIVE
To investigate the relationship between cognitive performance, affective state, metabolic syndrome and 7-year follow-up self-rated health (SRH) and perceived life satisfaction (PLS).


METHODS
Analysis of a prospective cohort study.


METHODS
The PROOF study, including 1011 elderly community residents.


METHODS
Six hundred and fifty seven subjects completed metabolic syndrome (Met S) variables, neuropsychological and affective measurements at baseline, and then returned a 7-year follow-up questionnaire which included SRH and PLS.


METHODS
The prospective association between cognitive function, Met S and each of its components, and affective disorders and subsequent subjective health and quality of life was examined. Covariates included educational level and use of tobacco. The analyses were made in men and women separately.


RESULTS
In multivariate models, the presence of Met S was significantly associated to weaker SRH (OR = 2.78, p = 0.009 in men and OR = 2.0, p = 0.02 in women). Higher triglycerides rate were associated with weaker SRH in men (OR = 2.23, p = 0.002) and higher fasting glucose in women (OR = 2.54, p = 0.006). Global Met S and abdominal obesity was significantly associated to weaker PLS in women only (respectively OR = 2.70, p = 0.0002 and OR = 1.9, p = 0.02). Depressive symptoms were significantly associated to both weaker SRH and PLS in men (OR = 1.30, p = 0.002; OR = 1.44, p < 0.0001 for SRH and PLS respectively) and in woman (OR = 1.09, p = 0.04; OR = 1.26, p < 0.0001 for SRH and PLS respectively). Anxiety was linked to both weaker SRH and PLS in women (OR = 1.17, p = 0.002 and 0R = 1.11, p = 0.03 for SRH and PLS respectively). Finally, lower executive function was associated with weaker PLS in men (OR = 0.43, p = 0.0005).


CONCLUSIONS
metabolic syndrome and certain of its components, anxiety and depressive symptoms, are independent predictors of poorer subjective health and quality of life as assessed over a period of 7 years in a population of a non-demented aging community. Moreover, executive performance was linked to subsequent quality of life in men. Many of these factors being treatable, our findings point to the necessity of providing preventive care strategies by the management of cardiovascular risk factors and anxio-depressive symptoms.
Isabelle Rouch, neurology unit, University Hospital of Saint-Etienne, 42055 Saint Etienne, France, isabelle.rouch@chu-st-etienne.fr.
I
I
Rouch
E
E
Achour-Crawford
F
F
Roche
C
C
Castro-Lionard
B
B
Laurent
G
G
Ntougou Assoumou
R
R
Gonthier
J-C
JC
Barthelemy
B
B
Trombert
D000339:Affect; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000523:psychology*; D001007:Anxiety / Q000453:epidemiology / Q000523:psychology; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000523:psychology; D003071:Cognition / Q000502:physiology*; D003863:Depression / Q000453:epidemiology / Q000523:psychology; D056344:Executive Function; D005260:Female; D005500:Follow-Up Studies; D006262:Health; D006304:Health Status; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology* / Q000523:psychology; D009765:Obesity / Q000453:epidemiology / Q000523:psychology; D016017:Odds Ratio; D010549:Personal Satisfaction; D011446:Prospective Studies; D011788:Quality of Life; D012307:Risk Factors; D057566:Self Report; D011795:Surveys and Questionnaires; D014280:Triglycerides / Q000097:blood
D014280:Triglycerides