Bull'S eye maculopathy in a patient taking sertraline.
OBJECTIVE
To report a very rare case of bilateral Bull's eye maculopathy caused by sertraline.


METHODS
Clinical case report and literature review.


METHODS
A 14-year-old girl.


RESULTS
A 14-year-old girl with no significant medical history developed bilateral Bull's eye maculopathy after taking sertraline for 1 year. Diagnostic work-up, which consisted of electrooculography, electroretinography, and genetic testing, yielded no abnormal results. Three-year follow-up examination after discontinuation of sertraline showed no improvement in visual acuity (20/200 bilaterally) or retinal pigment epithelium. This is the second published case, and according to the National Registry of Drug-Induced Ocular Side Effects, this is only the fifth reported case of presumed sertraline maculopathy.


CONCLUSIONS
Although Bull's eye maculopathy related to sertraline is rare, physicians and patients need to be aware of the possible toxicity.
*Department of Ophthalmology, University of Alabama School of Medicine, Birmingham, Alabama; and †Retina Consultants of Alabama, Callahan Eye Foundation Hospital, Birmingham, Alabama.
John O
JO
Mason
Shyam A
SA
Patel
D000293:Adolescent; D000928:Antidepressive Agents / Q000009:adverse effects; D001007:Anxiety / Q000188:drug therapy; D003937:Diagnosis, Differential; D004596:Electroretinography; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008268:Macular Degeneration / Q000139:chemically induced* / Q000175:diagnosis; D055213:Retinal Pigment Epithelium / Q000473:pathology*; D020280:Sertraline / Q000009:adverse effects* / Q000627:therapeutic use; D014792:Visual Acuity
D000928:Antidepressive Agents; D020280:Sertraline