Identical twins with lumbosacral lipomyelomeningocele.
Lipomyelomeningocele, a congenital spine defect, is presented as skin-covered lipomatous tissue that attaches to the cord in different ways according to its subtypes. Unlike other types of neural tube defects, the exact cause of this birth defect has not been confirmed yet, but it is proposed to be a multifactorial disease with involvement of both genetic and environmental factors. The authors describe identical twins with lipomyelomeningocele of the same subtype and location without any familial history of similar abnormality. Therefore, the same genetic and/or environmental risk factors could have played a part in their condition.
Department of Neurosurgery, Children's Hospital Medical Center, Tehran University of Medical Sciences;
Sara
S
Hanaei
Farideh
F
Nejat
Abolghasem
A
Mortazavi
Zohreh
Z
Habibi
Arash
A
Esmaeili
Mostafa
M
El Khashab
D003241:Consanguinity; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008591:Meningomyelocele / Q000175:diagnosis* / Q000601:surgery*; D012307:Risk Factors; D016896:Treatment Outcome; D014430:Twins, Monozygotic
LMMC = lipomyelomeningocele; MMC = myelomeningocele; NTD = neural tube defect; congenital; etiology; genetics; lipomyelomeningocele; neural tube defects; risk factors