Central retinal vein occlusion in a young adult during risperidone therapy.
BACKGROUND
Various articles in the literature point out the higher risk of venous thrombosis in patients taking antipsychotic drugs. However, to our knowledge, an association with central retinal vein occlusion (CRVO) has not been reported before.


METHODS
We describe the clinical and angiographic findings of a patient with CRVO that may have been related to his antipsychotic medication.


RESULTS
A 19-year-old patient had been taking risperidone and fluoxetine for the last 7 months. He presented with atypical nonischemic CRVO with atypical deep intraretinal hemorrhages, a swollen optic disk, dilatation and engorgement of retinal veins, and optic disk capillaries. Despite a detailed workup, no systemic or ocular risk factors for a thromboembolic event were found. He had hyperprolactinemia resulting from his medication.


CONCLUSIONS
The use of risperidone may be a risk factor for CRVO.
From *Beyoğlu Eye Research and Education Hospital, Eye Clinic; and †Marmara University Medical Faculty, School of Medicine, Department of Child and Adolescent Psychiatry, Istanbul, Turkey.
Alper
A
Ağca
Zerrin
Z
Bayraktar
Mehmet
M
Cakr
Sükrü
S
Bayraktar
Ozalp
O
Ekinci
Omer Faruk
OF
Ylmaz