Association between maternal periodontitis and preterm and/or low birth weight infants in normal pregnancies.
OBJECTIVE
To relate the periodontal condition with the presence of periodontal bacteria in pregnant that had babies with preterm delivery or/and low weight at birth (PTLBW).


METHODS
We recruited 134 pregnant women without systemic diseases attending at the Gynaecology and Obstetrics Room, from Maternal Provincial Hospital, Córdoba, Argentine. Pregnant were grouped according to the International Classification for a System of Periodontal Disease. A sample from periodontal pocket was extracted to identify Porphyromonas gingivalis (Pg), Treponema denticola (Td), Tannerella forsythia (Tf) Prevotella intermedia (Pi) and Agreggatibacter actinomycemcomitans (Aa).


RESULTS
We identified 7 (5%) cases of children born underweight or preterm of mothers diagnosed with Gingivitis, 6 (4%) in Mild Periodontitis and 4 (3%) in Moderate Periodontitis. We estimated that when Pi and/or Aa were not detected in the periodontal pockets of mothers, the infants had more than 129% chance of having normal birth weights (OR 3.47 for Pi and OR and 2.29 for Aa). The average age of the mothers who has PTLBW was 21 ± 3.5. The age showed an association with PTLBW (p < 0.0008).


CONCLUSIONS
The presences of periodontal pathogens in periodontal pockets from pregnant with different periodontal status would associate with PTLBW infants when the mothers are young, and the normal term and normal birth weight infant are associated with the absence of periodonto bacteria like Pi and Aa.
a Department of Periodontics , School of Dentistry .
María Matilde
MM
Usin
a Department of Periodontics , School of Dentistry .
Julieta
J
Menso
b Department of Biochemistry and Molecular Biology , School of Medical Sciences , and.
Verónica Inés
VI
Rodríguez
c Department of Biostatistics , School of Exact, Physical and Natural Sciences, National University of Cordoba , Córdoba , Argentina.
Analía
A
González
b Department of Biochemistry and Molecular Biology , School of Medical Sciences , and.
Sandra
S
Tabares
a Department of Periodontics , School of Dentistry .
Ricardo
R
Parodi
b Department of Biochemistry and Molecular Biology , School of Medical Sciences , and.
Adela
A
Sembaj
D000293:Adolescent; D000328:Adult; D001724:Birth Weight; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D010518:Periodontitis / Q000150:complications* / Q000382:microbiology; D011247:Pregnancy; D047928:Premature Birth / Q000382:microbiology*; D055815:Young Adult
Low birth weight infant; periodontal pathogens; periodontitis; preterm birth