Mitral valve surgery in patients with systemic lupus erythematosus.
Valvular heart disease is the common cardiac manifestation of systemic lupus erythematosus (SLE) with a tendency for mitral valve regurgitation. In this study we report a case of mitral valve replacement for mitral stenosis caused by Libman-Sacks endocarditis in the setting of SLE. In addition, we provide a systematic review of the literature on mitral valve surgery in the presence of Libman-Sacks endocarditis because its challenge on surgical options continues. Surgical decision depends on structural involvement of mitral valve and presence of active lupus nephritis and antiphospholipid antibody syndrome. Review of the literature has also shown that outcome is good in most SLE patients who have undergone valvular surgery, but association of antiphospholipid antibody syndrome with SLE has negative impact on the outcome.
Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, Iran.
Mahnoosh
0000-0002-5053-0793
M
Foroughi
Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, Iran.
Manouchehr
M
Hekmat
Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, Iran.
Mohsen
M
Ghorbani
Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, Iran.
Hamid
H
Ghaderi
Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, Iran.
Masoud
M
Majidi
Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, Iran.
Mahmood
M
Beheshti
D000293:Adolescent; D005260:Female; D019918:Heart Valve Prosthesis Implantation / Q000639:trends; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D008946:Mitral Valve Stenosis / Q000150:complications / Q000175:diagnosis / Q000601:surgery*