Indocyanine green angiography features of central areolar choroidal dystrophy.
OBJECTIVE
Central areolar choroidal dystrophy is an inherited autosomal dominant macular disease characterized by a central atrophy of the retinal pigment epithelium and choriocapillaris. Our purpose was to describe fluorescein angiography and confocal indocyanine green angiography features of central areolar choroidal dystrophy.


METHODS
We performed a complete ophthalmologic examination including best corrected visual acuity, fundus examination, color fundus photographs, red free frames, fluorescein angiography, infrared, confocal indocyanine green, and electroretinography in a cohort of patients with a family history of central areolar choroidal dystrophy.


RESULTS
Eleven patients (22 eyes) affected were prospectively included. Indocyanine green differentiated two distinct phenotypes. In 9/11 patients, atrophy area was hyperfluorescent or normofluorescent. In the two other patients, the lesion was hypofluorescent from early to late phases and pinpoints were observed on the late phases.


CONCLUSIONS
In our small series, indocyanine green angiography distinguished two phenotypes of central areolar choroidal dystrophy, correlated with fluorescein angiography features.
From the Clinique Ophtalmologique Universitaire de Créteil, Hôpital Intercommunal, Créteil, France.
Benjamin
B
Guigui
Oudy
O
Semoun
Giuseppe
G
Querques
Gabriel
G
Coscas
Gisèle
G
Soubrane
Eric H
EH
Souied