Postoperative choroidal hemorrhage shows elevated concentration of tissue plasminogen activator.
OBJECTIVE
The purpose of this study was to report the levels of tissue plasminogen activator in liquefied suprachoroidal hemorrhage.


METHODS
An interventional case report of a 61-year-old woman who underwent drainage sclerotomy for choroidal hemorrhage.


RESULTS
A 61-year-old pseudophakic woman underwent pars plana vitrectomy and fluid-gas exchange for retinal detachment in her right eye and developed postoperative serous choroidal detachments with large hemorrhages. Drainage sclerotomy was performed 18 days after the initial development of suprachoroidal hemorrhage. Sample of the liquefied hemorrhage and serum sample collected during sclerotomy were tested for tissue plasminogen activator levels using the antibody tissue plasminogen activator-enzyme immunoassay test. Hemorrhage tissue plasminogen activator levels were three times the levels present in the serum.


CONCLUSIONS
Tissue plasminogen activator may be involved in the process of suprachoroidal hemorrhage liquefaction.
*Division of Ophthalmology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts †Maine Vitreoretinal Consultants, Bangor, Maine.
Sushant
S
Wagley
Juliet
J
Yuan
Deborah S
DS
Hoffert
Jorge G
JG
Arroyo