Artificial pneumothorax in CT-guided radioactive iodine-125 seed implantation in the treatment of mediastinal tumors.
OBJECTIVE
To explore the efficacy and safety of CT-guided radioactive Iodine-125 seed implantation in treating mediastinal tumors in the thorax with artificial pneumothorax.


METHODS
Artificial pneumothorax was created using the 22 G thoracic puncture needle in 36 patients with mediastinal tumors, followed by CT-guided radioactive Iodine-125 seed implantation. An equal volume of gas was extracted after the treatment.


RESULTS
The treatment was completed in 35 patients. The tumor target volumes for the radiation treatment were not significantly different before and after the artificial pneumothorax (p = 0.265). No severe complications such as refractory pneumothorax, hemoptysis, or diffuse hemorrhage in the implantation area was observed.


CONCLUSIONS
Artificial pneumothorax can reduce the CT image interference caused by the needle tract bleeding during the radioactive Iodine-125 implantation.
Cancer Center, Institute of Surgical Research, Daping Hospital, Third Military Medical University, Chongqing, China. wangge70@hotmail.com.
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Zhang
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Yang
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Ma
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Hu
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Huang
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Wang
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000008:administration & dosage*; D008297:Male; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D008875:Middle Aged; D011031:Pneumothorax, Artificial / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D016896:Treatment Outcome
D007457:Iodine Radioisotopes