Monitoring the reduced scattering coefficient of bone tissues on the trajectory of pedicle screw placement using near-infrared spectroscopy.
Pedicle screw (PS) fixation has been widely used for spine diseases. Scientists and clinicians employ several approaches to navigate PS during operation. We have demonstrated the feasibility of monitoring the reduced scattering coefficient (μ's) on the trajectory of PS using near-infrared spectroscopy (NIRS). To perform the in-vitro monitoring, an NIRS measurement system was introduced and the reduced scattering coefficients of different sites in porcine pedicle were accurately deduced from the spectrum. Moreover, the changes of the reduced scattering coefficient along the different paths were studied. The results show reduced scattering coefficients on different regions of bones can be significantly distinguished. Furthermore, monitoring experiments along different paths confirmed that a reduced scattering coefficient would change versus the depth of puncture in pedicles. Thus, the proposed monitoring system based on NIRS provides a potential for guiding PS during operation.
Nanjing University of Aeronautics and Astronautics, Department of Biomedical Engineering, 29 Yudao Street, Nanjing 210016, China.
Yangyang
Y
Liu
Nanjing University of Aeronautics and Astronautics, Department of Biomedical Engineering, 29 Yudao Street, Nanjing 210016, China.
Yuyan
Y
Wang
Nanjing University of Aeronautics and Astronautics, Department of Biomedical Engineering, 29 Yudao Street, Nanjing 210016, China.
Zhiyu
Z
Qian
Nanjing University of Aeronautics and Astronautics, Department of Biomedical Engineering, 29 Yudao Street, Nanjing 210016, China.
Jinzhe
J
Zhao
Nanjing University of Aeronautics and Astronautics, Department of Biomedical Engineering, 29 Yudao Street, Nanjing 210016, ChinabNanjing General Hospital, 305 Zhongshan East Road, Nanjing 210016, China.
Xinzhi
X
Cao
Nanjing University of Aeronautics and Astronautics, Department of Biomedical Engineering, 29 Yudao Street, Nanjing 210016, China.
Weitao
W
Li
D000818:Animals; D001842:Bone and Bones / Q000737:chemistry / Q000502:physiology / Q000601:surgery; D065289:Pedicle Screws; D012542:Scattering, Radiation; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D013552:Swine