Rhodium(III)-catalyzed C-H/C-C activation sequence: vinylcyclopropanes as versatile synthons in direct C-H allylation reactions.
Succession of C-H activation and C-C activation was achieved by using a single rhodium(III) catalyst. Vinylcyclopropanes were used as versatile coupling partners. Mechanistic studies suggest that the olefin insertion step is rate-determining and a facile β-carbon elimination is involved, which represents a novel ring opening mode of vinylcyclopropanes.
School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. wanghg3@mail.sysu.edu.cn ceshzs@mail.sysu.edu.cn.
Jia-Qiang
JQ
Wu
Zhi-Ping
ZP
Qiu
Shang-Shi
SS
Zhang
Jing-Gong
JG
Liu
Ye-Xing
YX
Lao
Lian-Quan
LQ
Gu
Zhi-Shu
ZS
Huang
Juan
J
Li
Honggen
H
Wang
D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D056831:Coordination Complexes / Q000737:chemistry; D003500:Cyclization; D003521:Cyclopropanes / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D010084:Oxidation-Reduction; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism; D014753:Vinyl Compounds / Q000737:chemistry
D056831:Coordination Complexes; D003521:Cyclopropanes; D014753:Vinyl Compounds; D002244:Carbon; D006859:Hydrogen; D012238:Rhodium