Influence of food patterns on endothelial biomarkers: a systematic review.
The purpose of this study was to conduct a systematic review on the association of food patterns (FPs) and endothelial biomarkers. An electronic literature search from 1990 to 2012 was conducted and reference lists and experts were consulted. Studies without dietary intervention and without language restrictions were considered. Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were employed. Methodological quality was assessed by Strengthening the Reporting of Observational Studies in Epidemiology guidelines. A total of 546 references were identified, of which 8 were finally included. Several FPs were identified. Healthy FPs (abundant in fruits and vegetables) had a beneficial impact on endothelial function as estimated by circulating levels of biomarkers such as C-reactive protein, soluble intercellular adhesion molecule 1, soluble vascular adhesion molecule 1, and E-selectin molecules. Westernized patterns (higher intakes of processed meats, sweets, fried foods, and refined grains) were positively associated with inflammation molecules and atherogenic promoters. The study of FPs in relation to endothelial function contributes to the development of dietary recommendations for improved cardiovascular health and therefore a better lifestyle.
Centro de Excelencia en Salud Cardiovascular para el Cono Sur (CESCAS/SACECH), Instituto de Efectividad Clínica y Sanitaria, Buenos Aires, Argentina; Facultad de Ciencias Médicas, Escuela de Nutrición, Universidad Nacional de Córdoba, Córdoba, Argentina.
María Daniela
MD
Defagó
Natalia
N
Elorriaga
Vilma Edith
VE
Irazola
Adolfo Luis
AL
Rubinstein
D015415:Biomarkers / Q000378:metabolism*; D004730:Endothelium, Vascular / Q000378:metabolism*; D005247:Feeding Behavior; D006801:Humans; D007249:Inflammation / Q000378:metabolism*; D012307:Risk Factors
D015415:Biomarkers