Deciphering the role of phytoalexins in plant-microorganism interactions and human health.
Phytoalexins are low molecular weight antimicrobial compounds that are produced by plants as a response to biotic and abiotic stresses. As such they take part in an intricate defense system which enables plants to control invading microorganisms. In this review we present the key features of this diverse group of molecules, namely their chemical structures, biosynthesis, regulatory mechanisms, biological activities, metabolism and molecular engineering.
Laboratory of Stress, Defenses and Plant Reproduction, Research Unit "Vines and Wines of Champagne", UPRES EA 4707, Department of Biology and Biochemistry, Faculty of Sciences, University of Reims, P.O. Box 1039, 51687 Reims cedex 02, France. philippe.jeandet@univ-reims.fr.
Philippe
P
Jeandet
Laboratory of Stress, Defenses and Plant Reproduction, Research Unit "Vines and Wines of Champagne", UPRES EA 4707, Department of Biology and Biochemistry, Faculty of Sciences, University of Reims, P.O. Box 1039, 51687 Reims cedex 02, France. claire.hebrard@univ-reims.fr.
Claire
C
Hébrard
Champagne Deville, 13 rue Carnot, Verzy 51380, France. mdevillegarrick@gmail.com.
Marie-Alice
MA
Deville
Laboratory of Stress, Defenses and Plant Reproduction, Research Unit "Vines and Wines of Champagne", UPRES EA 4707, Department of Biology and Biochemistry, Faculty of Sciences, University of Reims, P.O. Box 1039, 51687 Reims cedex 02, France. sylvain.cordelier@univ-reims.fr.
Sylvain
S
Cordelier
Laboratory of Stress, Defenses and Plant Reproduction, Research Unit "Vines and Wines of Champagne", UPRES EA 4707, Department of Biology and Biochemistry, Faculty of Sciences, University of Reims, P.O. Box 1039, 51687 Reims cedex 02, France. stephan.dorey@univ-reims.fr.
Stéphan
S
Dorey
Laboratory of Stress, Defenses and Plant Reproduction, Research Unit "Vines and Wines of Champagne", UPRES EA 4707, Department of Biology and Biochemistry, Faculty of Sciences, University of Reims, P.O. Box 1039, 51687 Reims cedex 02, France. aziz.aziz@univ-reims.fr.
Aziz
A
Aziz
Laboratory of Stress, Defenses and Plant Reproduction, Research Unit "Vines and Wines of Champagne", UPRES EA 4707, Department of Biology and Biochemistry, Faculty of Sciences, University of Reims, P.O. Box 1039, 51687 Reims cedex 02, France. jerome.crouzet@univ-reims.fr.
Jérôme
J
Crouzet
D000890:Anti-Infective Agents / Q000378:metabolism*; D006801:Humans; D057865:Plant Immunity / Q000502:physiology*; D010944:Plants / Q000378:metabolism* / Q000382:microbiology*; D012717:Sesquiterpenes / Q000378:metabolism*; D013312:Stress, Physiological / Q000502:physiology*; D000094162:Phytoalexins
D000890:Anti-Infective Agents; D012717:Sesquiterpenes; D000094162:Phytoalexins