Hyperimmunoglobulin E syndrome in two siblings.
Hyperimmunoglobulin E recurrent infection syndrome (HIES) is characterized by recurrent skin and lung infections, eczema, elevated serum immunoglobulin E (IgE) levels (>2000 IU/mL), various connective tissue, skeletal, and vascular abnormalities.(1) We describe herein two brothers with HIES and documented the complications and management of such involvement.
Dermatology Department, La Rabta Hospital, Faculté de Médecine, Université El Manar, Tunis, Tunisia.
Abdulmohti
A
Hawilo
Dermatology Department, La Rabta Hospital, Faculté de Médecine, Université El Manar, Tunis, Tunisia.
Inès
I
Zaraa
Dermatology Department, La Rabta Hospital, Faculté de Médecine, Université El Manar, Tunis, Tunisia.
Sondes
S
Trojjet
Dermatology Department, La Rabta Hospital, Faculté de Médecine, Université El Manar, Tunis, Tunisia.
Hella
H
Zribi
Dermatology Department, La Rabta Hospital, Faculté de Médecine, Université El Manar, Tunis, Tunisia.
Rym Cheikh
RC
Rouhou
Dermatology Department, La Rabta Hospital, Faculté de Médecine, Université El Manar, Tunis, Tunisia.
Dalenda El
DE
Euch
Dermatology Department, La Rabta Hospital, Faculté de Médecine, Université El Manar, Tunis, Tunisia.
Mourad
M
Mokni
Dermatology Department, La Rabta Hospital, Faculté de Médecine, Université El Manar, Tunis, Tunisia.
Amel Ben
AB
Osman
atopic dermatitis; hyper-IgE syndrome; infection.; primary immunodeficiency