Congenital optic nerve anomaly and migration of subretinal oil: case report and observations in one family.
OBJECTIVE
To describe a case of optic nerve (ON) anomaly and retinal detachment with extensive subretinal silicone oil after repair of retinal detachment. A three-generation family history of ON anomaly, two generations with detachment, is presented.


METHODS
Retrospective chart review. A multigenerational family with ON anomalies and macular detachment.


RESULTS
Final repair of retinal detachment was achieved using retinotomy for removal of subretinal 5,000-centistoke silicone oil, gas-fluid exchange, and peripapillary photocoagulation. Silicone oil had been previously used successfully in this eye, yet on subsequent use resulted in subretinal migration. A four patient-three-generation family history of ON anomalies was elicited, and three members were photographed for documentation.


CONCLUSIONS
Optic nerve anomalies and macular detachment present a treatment dilemma because they are associated with poor vision and often a suboptimal visual outcome after surgery. This case demonstrates a large amount of subretinal silicone oil, which migrated over a 2-month period. This case series is a report of a three-generational family demonstrating variable expressivity of ON anomalies complicated by macular detachment in two generations.
*Retina Vitreous Associates Medical Group, Los Angeles, California; and †Jules Stein Eye Institute, University of California Los Angeles, Los Angeles, California.
Michelle V
MV
Carle
Michael C
MC
Rahhal
Firas M
FM
Rahhal
D000293:Adolescent; D005260:Female; D006801:Humans; D009900:Optic Nerve / Q000002:abnormalities*; D009901:Optic Nerve Diseases / Q000150:complications*; D010375:Pedigree; D012163:Retinal Detachment / Q000601:surgery*; D012827:Silicone Oils / Q000009:adverse effects*; D014821:Vitrectomy / Q000009:adverse effects*
D012827:Silicone Oils