Sexual transmission of oral human papillomavirus infection among men.
We estimated the prevalence of oral human papillomavirus (HPV) and assessed risk factors among young heterosexual men participating in the HPV Infection and Transmission among Couples through Heterosexual Activity (HITCH) study. Oral and genital HPV samples were collected from 222 men and their female partners who were participating in the HITCH study, a longitudinal cohort on HPV transmission among heterosexual couples. Demographic and behavioral data were collected through self-administered computer questionnaires and biologic samples were tested with the Linear Array for HPV. Outcome measures were overall and type-specific prevalence of oral HPV. The prevalence of oral HPV among men was 7.2% and was higher among men who were ever smokers (12.2%), in nonmonogamous relationships (17.9%), or had a partner with oral (28.6%) and/or genital (11.5%) HPV infection. Moreover, prevalence increased with frequency of oral sex among men whose partner who had a genital infection with the same HPV type. Our results provide further evidence that oral HPV may be transmitted through either oral-oral or oral-genital routes.
Department of Oncology, McGill University, Montreal, Quebec, Canada.
Kristina R
KR
Dahlstrom
Department of Oncology, McGill University, Montreal, Quebec, Canada. Ontario HIV Treatment Network, Toronto, Ontario, Canada.
Ann N
AN
Burchell
Department of Oncology, McGill University, Montreal, Quebec, Canada.
Agnihotram V
AV
Ramanakumar
Department of Oncology, McGill University, Montreal, Quebec, Canada.
Allita
A
Rodrigues
Department of Family Medicine, McGill University, Montreal, Quebec, Canada.
Pierre-Paul
PP
Tellier
Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Quebec, Canada.
James
J
Hanley
Department of Oncology, McGill University, Montreal, Quebec, Canada. Department of Microbiology and Immunology, University of Montreal, Montreal, Quebec, Canada.
François
F
Coutlée
Department of Oncology, McGill University, Montreal, Quebec, Canada. Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Quebec, Canada. eduardo.franco@mcgill.ca.
Eduardo L
EL
Franco
D000293:Adolescent; D015331:Cohort Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D027383:Papillomaviridae / Q000235:genetics; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000821:virology*; D015995:Prevalence; D012307:Risk Factors; D012725:Sexual Behavior; D012749:Sexually Transmitted Diseases; D055815:Young Adult