Intrauterine device may trigger typical attacks of familial Mediterranean fever: a case report.
Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by episodic, recurrent, self-limited attacks of fever and serositis (sterile peritonitis, pleuritis, arthritis, etc). The insufficiency in restriction of mild inflammation contributes this consequence in FMF.Intrauterine devices (IUDs) have been widely used in the world for contraception by gynecologists as an effective and safe method. Herein, we present a woman with FMF as the first case, whose attacks were triggered by copper-containing IUD. Our hypothesis in the present case was that sterile mild inflammation in the uterus caused by copper-containing IUD may be the initial source of systemic inflammatory response.In our opinion, clinicians should consider that the copper-containing IUDs may be another cause of FMF attacks in women using this contraceptive method.
Department of Nephrology, Gulhane Military Academy of Medicine, Haydarpasa Training Hospital, Istanbul, Turkey, ilhankurultak@yahoo.co.uk.
Ilhan
I
Kurultak
Can
C
Kinalp
Mevlut
M
Ceri
Tevfik Rıfkı
TR
Evrenkaya
D000328:Adult; D003300:Copper / Q000009:adverse effects*; D003937:Diagnosis, Differential; D010505:Familial Mediterranean Fever / Q000139:chemically induced* / Q000175:diagnosis* / Q000517:prevention & control; D005260:Female; D006801:Humans; D007435:Intrauterine Devices, Copper / Q000009:adverse effects*
D003300:Copper