Molecular typing tools: from pattern recognition to genome-based algorithms.
In the present chapter, we discuss DNA-based typing methods for microbial pathogens that were frequently used in the past two decades and their essential features, as well as virtues and downsides. We conclude with an outlook on the fundamental changes that can be expected in the era of high-throughput genomics.
Friedrich-Loeffler-Institut (Federal Research Institute for Animal Health), Institute of Molecular Pathogenesis, Naumburger Str. 96a, 07743, Jena, Germany, konrad.sachse@fli.bund.de.
Konrad
K
Sachse
Petra
P
Moebius
D023281:Genomics / Q000379:methods*; D008828:Microbiological Techniques / Q000379:methods; D058889:Molecular Typing / Q000379:methods*; D010363:Pattern Recognition, Automated / Q000379:methods*