Primary glioblastoma of the trigeminal nerve root entry zone: case report.
Gliomas of the cranial nerve root entry zone are rare clinical entities. There have been 11 reported cases in the literature, including only 2 glioblastomas. The authors report the case of a 67-year-old man who presented with isolated facial numbness and was found to have a glioblastoma involving the trigeminal nerve root entry zone. After biopsy the patient completed treatment with conformal radiation and concomitant temozolomide, and at 23 weeks after surgery he demonstrated symptom progression despite the treatment described. This is the first reported case of a glioblastoma of the trigeminal nerve root entry zone.
Departments of 1 Neurological Surgery and.
Jonathan D
JD
Breshears
Michael E
ME
Ivan
Jennifer A
JA
Cotter
Andrew W
AW
Bollen
Phillip V
PV
Theodosopoulos
Mitchel S
MS
Berger
D000368:Aged; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use; D059248:Chemoradiotherapy; D003131:Combined Modality Therapy; D003390:Cranial Nerve Neoplasms / Q000601:surgery / Q000628:therapy*; D003606:Dacarbazine / Q000031:analogs & derivatives / Q000627:therapeutic use; D018450:Disease Progression; D005909:Glioblastoma / Q000601:surgery / Q000628:therapy*; D006801:Humans; D008297:Male; D000077204:Temozolomide; D020433:Trigeminal Nerve Diseases / Q000601:surgery / Q000628:therapy*
D018906:Antineoplastic Agents, Alkylating; D003606:Dacarbazine; D000077204:Temozolomide
CN = cranial nerve; brainstem; cranial nerve; glioblastoma; oncology; root entry zone; trigeminal nerve