Diffuse choroidal melanocytoma simulating melanoma in a child with ocular melanocytosis.
OBJECTIVE
To report a clinicopathologic correlation of an extensive, diffuse uveal melanocytoma (magnocellular nevus) simulating diffuse choroidal melanoma in a child.


METHODS
Clinicopathologic report.


RESULTS
A 14-year-old girl with congenital sector ocular melanocytosis was found to have progressive visual loss and a diffuse choroidal mass measuring 18 mm in basal dimension and 4 mm in thickness. There was overlying orange pigment and secondary retinal detachment. Diffuse choroidal melanoma was suspected, and the eye was enucleated. Histopathologically, the entire uveal tract was diffusely thickened because of a proliferation of benign cells typical of melanocytoma without evidence of melanoma.


CONCLUSIONS
Diffuse uveal melanocytoma is a rare variant of ocular melanocytosis that can cause reduced vision, overlying orange pigment, and retinal detachment, resembling a diffuse choroidal melanoma.
From the *Oncology Service and †Department of Pathology, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania; and the ‡Department of Ophthalmology, Kresge Eye Institute, Wayne State University, Detroit, Michigan.
Jerry A
JA
Shields
Ralph C
RC
Eagle
Carol L
CL
Shields
Gary
G
Abrams