Testicular mixed germ-cell tumor metastatic to the choroid.
OBJECTIVE
To describe the fundus findings, ultrasonography, and fluorescein angiography of a testicular mixed germ-cell tumor metastatic to the choroid and to report prompt resolution of the choroidal lesion with systemic chemotherapy.


METHODS
Observational case report. A 21-year-old man presented with a 10-cm testicular tumor. Ophthalmic examination revealed a large, dome-shaped choroidal lesion in the left eye, filling the entire superotemporal quadrant and extending into the macula. Ultrasonography showed a 10.3 mm in thickness hyperechoic mass. The patient was started on vinblastine, mesna, ifosfamide, and cisplatin.


RESULTS
On ophthalmic examination 6 weeks after initiation of chemotherapy, the choroidal lesion had completely resolved, leaving only pigmentary changes. Final ophthalmology follow-up 8 months after presentation demonstrated no recurrence of choroidal metastases.


CONCLUSIONS
Testicular germ-cell tumors have now been well described to metastasize to the choroid. These choroidal metastases can show a prompt, favorable response to chemotherapy.
From the Departments of *Ophthalmology & Visual Sciences and †Urology, University of Illinois at Chicago.
Mohammed K
MK
ElMallah
Allen M
AM
Chernoff
Norman P
NP
Blair