Hemorrhagic Transformation of Scrub Typhus Encephalitis: A Rare Entity.
Central nervous system (CNS) involvement of scrub typhus infection is well known. Most CNS involvement of scrub typhus infection present as meningitis or encephalitis. We report on a patient suffering from hemorrhagic transformation of intracranial lesions caused by Orientia tsutsugamushi. A 53-year-old female farmer who was infected by scrub typhus was treated with doxycycline and recovered from the systemic illness. However, headache persisted. Brain radiologic studies revealed acute intracranial hemorrhage and enhancing lesion, which implied a CNS involvement. Hemorrhagic transformation of encephalitis by scrub typhus is very rare complication and to our best knowledge, this is the first report of hemorrhagic transformation of scrub typhus encephalitis. Clinician should consider the possibility of hemorrhagic transformation of encephalitis in cases of scrub typhus infection.
Department of Neurosurgery, Dankook University College of Medicine, 201 Manghyang-ro Dongnam-gu, 330-715, Cheonan, Chungnam, Republic of Korea.
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Kim
Department of Neurosurgery, Dankook University College of Medicine, 201 Manghyang-ro Dongnam-gu, 330-715, Cheonan, Chungnam, Republic of Korea.
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Yoon
Department of Neurosurgery, Dankook University College of Medicine, 201 Manghyang-ro Dongnam-gu, 330-715, Cheonan, Chungnam, Republic of Korea.|Department of Radiology, Dankook University College of Medicine, Cheonan, Chungnam, Republic of Korea.
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DS
Yoo
Department of Neurosurgery, Dankook University College of Medicine, 201 Manghyang-ro Dongnam-gu, 330-715, Cheonan, Chungnam, Republic of Korea. babyface@dankook.ac.kr.
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Cho
D002543:Cerebral Hemorrhage / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D000069544:Infectious Encephalitis / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D008279:Magnetic Resonance Imaging / Q000379:methods; D008875:Middle Aged; D035583:Rare Diseases / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D012612:Scrub Typhus / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D014057:Tomography, X-Ray Computed / Q000379:methods