Progressive outer retinal necrosis complicated by combined central retinal vein and central retinal artery occlusions.
OBJECTIVE
To describe an uncommon presentation and course of progressive outer retinal necrosis.


METHODS
A 36-year-old man presented with unilateral optic disk edema with enhancement of the optic nerve sheath shown by magnetic resonance imaging. Intravenous methylprednisolone treatment was initiated.


RESULTS
Two days later, he developed multiple discrete areas of outer retinal opacification with areas of confluence in the periphery of the retina. Results of laboratory testing for antibody to human immunodeficiency virus were positive. Therapy for progressive outer retinal necrosis was initiated, and the patient developed combined central retinal vein and central retinal artery occlusions 3 days later.


CONCLUSIONS
Although usually characterized by a lack of vascular inflammation, progressive outer retinal necrosis may lead to vascular occlusions.
From the Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas.
Phuong T
PT
Tran
Robert W
RW
Crow
Preston H
PH
Blomquist
Yu-Guang
YG
He