[Analysis of incidence and mortality of thyroid cancer in China, 2010].
OBJECTIVE
To analysis the incidence and mortality status of thyroid cancer in China, 2010.


METHODS
Incidence and mortality data of thyroid cancer were derived from 145 cancer registries in China of 2010.Incidences, mortality, age-specific rates of thyroid cancer in different areas (urban and rural) were calculated. The incident cases and deaths were estimated using age-specific rates and national population data. Chinese census in 2000 and Segi's population were used for age-standardized incidence and mortality rates.


RESULTS
The registration areas covered a total of 158 403 248 population (92 433 739) in urban areas and 65 969 509 in rural areas, which accounted for 12.05% (158 403 248/1 314 873 293) of the total population of the whole country in 2010. The estimates of new cancer incident cases was 54 175 (male 12 962, female 41 213), with the crude incidence rate of 4.12/100 000 (54 175/1 314 873 293). Age-standardized incidence rates by Chinese standard population (ASIRC, 2000) and by world standard population (ASIRW) were 3.62/100 000 and 3.23/100 000, respectively, which accounted for 1.75% (54 175/3 093 039) of all malignant tumors in 2010. Male to female ratio was 1: 3.2, the incidence rate in urban areas was 1.46 times higher than that of rural areas. The estimates number of cancer deaths was 4 504 (male 1 529 cases and female 2 975 cases) in 2010 in China with the crude mortality rate of thyroid cancer 0.34/100 000 (4 504/1 314 873 293). Age-standardized mortality rates by Chinese standard population (ASIRC, 2000) and by world standard population (ASIRW) were 0.27/100 000 and 0.26/100 000, respectively, which accounted for 0.23% (4 504/1 956 662) of all malignant related deaths. The cumulative incidence and mortality rates (0-74 years old) were 0.32% and 0.03%, respectively. According to the data from 145 cancer registries, papillary carcinoma was the main pathology type, which accounted for 86.0% (6 237/7 253) of all malignant tumors.


CONCLUSIONS
The incidence and mortality rates of thyroid cancer in urban areas of China were higher than that in rural areas, and females had higher incidence rate of thyroid than males. The reasons related the higher incidence rate of thyroid cancer in urban China should be paid more attention to in the future.
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing Office for Cancer Prevention and Control, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Lei
L
Yang
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing Office for Cancer Prevention and Control, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Rongshou
R
Zheng
Ning
N
Wang
Siwei
S
Zhang
Email: chenwq@cicams.ac.cn.
Wanqing
W
Chen
D000293:Adolescent; D000368:Aged; D002291:Carcinoma, Papillary; D002648:Child; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D009369:Neoplasms; D012042:Registries; D012424:Rural Population; D013964:Thyroid Neoplasms / Q000453:epidemiology* / Q000401:mortality*; D014505:Urban Population