Epidemiology of female reproductive cancers in Iran: results of the Gholestan Population-based Cancer Registry.
BACKGROUND
Malignancies of the female reproductive tract are estimated to be the third most common group of cancers in women.


OBJECTIVE
We here aimed to present their epidemiological features in Golestan province located in Northeast of Iran.


METHODS
Data on primary female reproductive cancers diagnosed between 2004-2010 were obtained from Golestan Population-based Cancer Registry (GPCR). CanReg-4 and SPSS software were used for data entry and analysis. Age standardized incidence rates (ASR) (per 100,000 person-years) were calculated using the world standard population. Poisson regression analysis was used to compare incidence rates. P-values of less than 0.05 were considered as significant.


RESULTS
A total of 6,064 cancer cases were registered in Golestan females in the GPCR during 2004-2010, of which 652 cases (11%) were female reproductive cancers. Cancers of the ovary (ASR=6.03) and cervix (ASR=4.97) were the most common. We found significant higher rates in females living in cities than in villages. Our results showed a rapid increase in age specific incidence rates of female reproductive cancers at the age of 30 years.


CONCLUSIONS
We found significant higher rates of female reproductive cancers among residents of cities than villages. Differences in the prevalence of risk factors including reproductive behavior between the two populations may partly explain such diversity. Our results also showed a rapid increase in incidence rates of these cancers in young age females. Further studies are warranted to determine risk factors of female reproductive cancers in our population.
Department of Obstetrics and Gynecology, Zahedan University of Medical Sciences, Zahedan, Iran E-mail : fazelabdolreza@gmail.com; grcgh@goums.ac.ir.
NegarSadat
N
Taheri
Abdolreza
A
Fazel
Habibollah
H
Mahmoodzadeh
Ramesh
R
Omranpour
Gholamreza
G
Roshandel
Saeedeh
S
Gharahjeh
Seyed Mehdi
SM
Sedaghat
Mohammad
M
Poorabbasi
Abbas
A
Moghaddami
Shahryar
S
Semnani
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007492:Iran / Q000453:epidemiology; D008875:Middle Aged; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000453:epidemiology* / Q000473:pathology; D010920:Placenta / Q000473:pathology*; D011247:Pregnancy; D011379:Prognosis; D012042:Registries; D012098:Reproduction; D014594:Uterine Neoplasms / Q000453:epidemiology* / Q000473:pathology; D055815:Young Adult