Assessment of health-related quality of life of patients after kidney transplantation in comparison with hemodialysis and peritoneal dialysis.
BACKGROUND
The quality of life may determine the efficacy of renal replacement therapy (RRT). The purpose of the study was to compare the health-related quality of life (HRQOL) of end-stage renal disease (ESRD) patients depending on RRT method.


METHODS
The studies were conducted on 120 patients divided into 3 groups depending on RRT method: 30 peritoneal dialysis (PD) patients, 40 hemodialysis (HD) patients, and 47 post-kidney transplantation (KTx) patients. The following research tools were used: (1) Medical Outcomes Study 36 - the Short Form (SF-36 v.1); (2) Kidney Disease Quality of Life Short Form (KDQOL-SF™ v.1.3); and (3) disease history. The relevance level was p<0.05.


RESULTS
The evaluation of PCS by HD and PD patients is poorer compared to patients in the 3rd and 12th month after KTx (34.7 ± 7.4 vs. 37.51 ± 10.63 vs. 45.01 ± 9.43 vs. 45.55 ± 8.62; p<0.05; respectively). PCS statistically significantly correlated with the following: SBP (r=-0.54; p<0.05), DBP (r=-0.58; p<0.05), and creatinine concentration (r=0.46; p<0.05) in the 12(th) month after KTx.


CONCLUSIONS
HRQOL of ESRD patients differed depending on the RRT method: top values were shown by post-KTx patients, lower by PD patients, and the bottom ones by HD patients. Along with patient age, increased BP, and BMI, a drop in value of HRQOL in post-Tx or PD patients was observed. When choosing RTT method, patients may use the results of the evaluation of quality of life. A preferred lifestyle, and predominantly the work status and quality of social interaction, should decide the choice of treatment.
Department of Anaesthesiology, Institute of Cardiology, Warsaw, Poland.
Lukasz
L
Czyżewski
Department of Nephrological Nursing, Medical University of Warsaw, Warsaw, Poland.
Joanna
J
Sańko-Resmer
Department of Nephrological Nursing, Medical University of Warsaw, Warsaw, Poland.
Janusz
J
Wyzgał
Department of Anaesthesiology, Institute of Cardiology, Warsaw, Poland.
Andrzej
A
Kurowski
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006305:Health Status Indicators; D006801:Humans; D007676:Kidney Failure, Chronic / Q000523:psychology / Q000628:therapy*; D016030:Kidney Transplantation / Q000523:psychology; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis / Q000523:psychology; D011446:Prospective Studies; D011788:Quality of Life / Q000523:psychology; D006435:Renal Dialysis / Q000523:psychology; D016896:Treatment Outcome; D055815:Young Adult