Development of coated blade spray ionization mass spectrometry for the quantitation of target analytes present in complex matrices.
Coated blade spray (CBS) is a technology based on solid-phase microextraction (SPME) that has been designed for the quick extraction/cleanup of analytes from complex matrices and direct desorption/ionization under ambient mass spectrometry conditions. The entire analytical process can be completed in less than 3 min and enables limits of quantitation in the low picogram-per-milliliter region to be reached.
Department of Chemistry, University of Waterloo, 200 University Avenue, Waterloo, N2L 3G1 (Canada) http://spme.uwaterloo.ca.
German Augusto
GA
Gómez-Ríos
Janusz
J
Pawliszyn
ambient ionization; coated blade spray; complex matrices; mass spectrometry; trace analysis