Genome Sequence of the Anterograde-Spread-Defective Herpes Simplex Virus 1 Strain MacIntyre.
We used paired-end Illumina deep sequencing and de novo assembly to determine the genome sequence of herpes simplex virus 1 (HSV-1) strain MacIntyre (aka McIntyre). The MacIntyre strain originated from the brain of a patient with lethal HSV encephalitis and has a unique limitation in its neuronal spread, moving solely in the retrograde direction.
moriah@psu.edu.
Moriah L
http://orcid.org/0000-0001-9859-1678
ML
Szpara
Department of Molecular Biology, the Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey, USA.
Yolanda R
YR
Tafuri
Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA.
Lance
L
Parsons
Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, USA.
Jacob T
JT
Shreve
Department of Molecular Biology, the Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey, USA.
Esteban A
EA
Engel
L W
LW
Enquist