Acute retinal necrosis after corticosteroid pulse therapy for unilateral vogt-koyanagi-harada disease.
OBJECTIVE
To report on a patient with unilateral Vogt-Koyanagi-Harada (VKH) disease who developed varicella zoster-associated acute retinal necrosis after corticosteroid pulse therapy for the VKH disease.


METHODS
Observational case report.


RESULTS
A 36-year-old Japanese man was diagnosed with incomplete VKH disease despite having only unilateral changes. After corticosteroid pulse therapy, the same eye developed acute retinal necrosis. Polymerase chain reaction of an aqueous humor specimen showed DNA of the varicella zoster virus. Seven days after intravenous acyclovir, the retinitis disappeared.


CONCLUSIONS
We encountered a rare case of unilateral VKH disease that developed acute retinal necrosis during corticosteroid pulse therapy. Acute retinal necrosis can develop during corticosteroid pulse therapy for VKH disease.
From the Department of Ophthalmology, Nagoya University School of Medicine, Showa-ku, Nagoya, Japan.
Reiko
R
Yokoi
Tetsu
T
Asami
Shu
S
Kachi
Yasuki
Y
Ito
Makoto
M
Nakamura
Hiroko
H
Terasaki