Corneal Biomechanical Characteristics in Patıents with Behçet Disease.
OBJECTIVE
To examine corneal biomechanical properties, intraocular pressure, and central corneal thickness in uveitic eyes with Behçet disease (BD) and to compare them with healthy controls.


METHODS
This study included 40 eyes of 34 patients with ocular BD and 20 eyes of 20 healthy controls. Eyes with ocular BD were subdivided into active and inactive groups. Ocular response analyzer (ORA) measurements were performed on the 20 eyes of 16 patients with active BD (group 1), 20 eyes of 18 patients with inactive BD (group 2), and 20 eyes of 20 healthy volunteers who served as the control group (group 3). Corneal hysteresis (CH), corneal resistance factor (CRF), intraocular pressure (Goldmann correlated [IOPg], and corneal compensated [IOPcc]) and central corneal thickness (CCT) values were recorded.


RESULTS
Mean age of patients in groups 1, 2, and 3 was 33.81 ± 9.36, 32.38 ± 9.08, and 31.05 ± 5.85 years, respectively (p = 0.76). Mean CH, CRF, IOPg, IOPcc, and CCT values in groups 1, 2, and 3 were [8.51 ± 1.88, 9.72 ± 2.11, 19.87 ± 2.92, 16.13 ± 3.29, and 592.50 ± 39.95], [8.46 ± 1.82, 8.45 ± 1.98, 15.89 ± 2.68, 15.35 ± 2.91, and 528.35 ± 19.18], and [8.47 ± 1.48, 8.43 ± 1.58, 15.59 ± 2.74, 15.42 ± 3.19, and 526.30 ± 18.21], respectively [(p1 = 0.040, 0.904, <0.001, 0.495 and <0.001 for CRF, CH, IOPg, IOPcc and CCT in group 1, respectively), (p2 = 0.989, 0.904, 0.659, 0.989, and 0.989 for CRF, CH, IOPg, IOPcc and CCT in group 2, respectively), (p3 = 0.989, 0.904, 0.660, 0.989, and 0.989 for CRF, CH, IOPg, IOPcc and CCT in group 3, respectively)].


CONCLUSIONS
CRF, IOPg, and CCT values altered in active BD group when compared with inactive BD and control group (p < 0.005). Further studies are required to establish the effects of BD on corneal biomechanical properties.
a Gozde Kisla Hospital , Malatya , Turkey.
Cem
C
Cankaya
a Gozde Kisla Hospital , Malatya , Turkey.
Bulent Nuri
BN
Kalayci
D000328:Adult; D001528:Behcet Syndrome / Q000503:physiopathology*; D001696:Biomechanical Phenomena; D003315:Cornea / Q000503:physiopathology*; D004548:Elasticity / Q000502:physiology*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D014065:Tonometry, Ocular
Behçet disease; central corneal thickness; corneal biomechanical characteristics; intraocular pressure; ocular response analyzer