The association of elevated mean platelet volume with the outcome of acute mesenteric ischemia.
Mesenteric ischemia is a life-threatening vascular emergency with high mortality rates. Mean platelet volume (MPV) has been shown to be closely related to platelet activation. We investigated whether MPV was associated with outcome of acute mesenteric ischemia (AMI). Sixty-one patients who were operated for AMI were retrospectively evaluated. Patients were divided into two groups: survivors and nonsurvivors, according to the outcome, and the two groups were compared in terms of MPV levels and other prognostic factors. Urea, creatinine, alkaline phosphatase, amylase, gamma-glutamyl transferase and MPV levels were significantly higher in nonsurvivors, when compared to that of survivors. In addition, hypertension, atherosclerotic heart diseases and rhythm disorders were statistically significant risk factors for mortality. AMI is an uncommon but highly lethal surgical emergency. Our results indicate that an elevated MPV is associated with a worse outcome in patients with AMI.
aDepartment of Surgery, Turgut Özal University, Medical School bDepartment of Surgery, Ankara Numune Teaching and Research Hospital cDepartment of Surgery, Hacettepe University, Medical School dDepartment of Internal Medicine, Division of Gastroenterology, Turgut Özal University, Medical School, Ankara, Turkey.
İsmail C
İC
Bilgiç
Sibel
S
Gelecek
Mehmet M
MM
Ozmen
Benan
B
Kasapoglu
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume / Q000009:adverse effects*; D065666:Mesenteric Ischemia / Q000097:blood*; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D016896:Treatment Outcome