[The genome and cancer treatment].
Basic research has uncovered the molecular pathogenesis of both sporadic and hereditary cancer and this has paved the way for the use of genome-wide technologies to depict the molecular drivers of individual tumours and for development of personalized and targeted treatment. This review describes the recent application of next generation sequencing and microarrays in the classification of cancers and the prospects of personalized medicine in oncology.
Klinisk Biokemi, Righospitalet, Blegdamsvej 9, 2100 København Ø. fcn@rh.dk.
Finn Cilius
FC
Nielsen
Ulrik
U
Lassen
D005820:Genetic Testing / Q000941:ethics; D015894:Genome, Human; D006801:Humans; D046228:Microarray Analysis; D009369:Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D028701:Patient Rights; D057285:Precision Medicine; D017422:Sequence Analysis, DNA