Electrochemical performance of porous diamond-like carbon electrodes for sensing hormones, neurotransmitters, and endocrine disruptors.
Porous diamond-like carbon (DLC) electrodes have been prepared, and their electrochemical performance was explored. For electrode preparation, a thin DLC film was deposited onto a densely packed forest of highly porous, vertically aligned multiwalled carbon nanotubes (VACNT). DLC deposition caused the tips of the carbon nanotubes to clump together to form a microstructured surface with an enlarged surface area. DLC:VACNT electrodes show fast charge transfer, which is promising for several electrochemical applications, including electroanalysis. DLC:VACNT electrodes were applied to the determination of targeted molecules such as dopamine (DA) and epinephrine (EP), which are neurotransmitters/hormones, and acetaminophen (AC), an endocrine disruptor. Using simple and low-cost techniques, such as cyclic voltammetry, analytical curves in the concentration range from 10 to 100 μmol L(-1) were obtained and excellent analytical parameters achieved, including high analytical sensitivity, good response stability, and low limits of detection of 2.9, 4.5, and 2.3 μmol L(-1) for DA, EP, and AC, respectively.
Department of Chemistry, Federal University of São Carlos , Rodovia Washington Luís km 235, 676, São Carlos, 13560-970, SP Brazil.
Tiago A
TA
Silva
Hudson
H
Zanin
Paul W
PW
May
Evaldo J
EJ
Corat
Orlando
O
Fatibello-Filho
D000082:Acetaminophen / Q000737:chemistry / Q000302:isolation & purification*; D015374:Biosensing Techniques / Q000379:methods; D004298:Dopamine / Q000737:chemistry / Q000302:isolation & purification*; D004566:Electrodes; D052244:Endocrine Disruptors / Q000737:chemistry / Q000302:isolation & purification; D004837:Epinephrine / Q000737:chemistry / Q000302:isolation & purification*; D006801:Humans; D037742:Nanotubes, Carbon / Q000737:chemistry*; D016062:Porosity; D013499:Surface Properties
D052244:Endocrine Disruptors; D037742:Nanotubes, Carbon; D000082:Acetaminophen; D004298:Dopamine; D004837:Epinephrine
aligned nanotubes scaffold; electroanalysis; fast charge transfer; porous DLC