Preemptive kidney transplantation: analysis of kidney grafts from the same donor.
BACKGROUND
From November 2003 to December 2012, in the Gdańsk Center, 64 patients received preemptive transplantation (PET). PET comprised 8% of 794 kidney transplantations performed during this time. The benefits for individual patients and for the health care system are discussed.


METHODS
This study compares the outcomes of these PET patients who had their kidney pairs transplanted after a variable duration of dialysis (PTD), a total of 51 pairs.


RESULTS
The mean Charlson comorbidity index was 2.57 vs 3.04 (P > .05) for the PET and PTD groups, respectively. Both groups did not differ significantly with respect to 1-year patient and graft survivals, and incidences of acute rejection. Five (9.8%) PET patients and 20 (39%) PTD patients experienced delayed graft function (P < .05). The graft function (serum creatinine/4p MDRD) 1 year after transplantation was similar in both groups (1.42/53.7 vs 1.43/57.4; mg/dL/mL/min/1.73 m(2)). More PET patients continued normal professional activities or education before and after transplantation (P < .05).


CONCLUSIONS
Our single-center results confirmed that for both medical and socioeconomic reasons, PET is an optimal mode of renal replacement therapy.
Department of Nephrology, Transplantology, and Internal Diseases, Medical University of Gdańsk, Gdańsk, Poland. Electronic address: adeb@gumed.edu.pl.
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Dębska-Ślizień
Department of Nephrology, Transplantology, and Internal Diseases, Medical University of Gdańsk, Gdańsk, Poland.
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Bzoma
Department of Clinical Immunology and Transplantology, Medical University of Gdańsk; Gdańsk, Poland.
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Moszkowska
Kidney Transplant Regional Waiting List, Department of General Nursing, Faculty of Medical Sciences, Medical University of Gdańsk, Gdańsk, Poland.
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Chamienia
Department of General, Endocrine, and Transplant Surgery, Medical University of Gdańsk; Gdańsk, Poland.
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Milecka
Department of General, Endocrine, and Transplant Surgery, Medical University of Gdańsk; Gdańsk, Poland.
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Zadrożny
Department of General, Endocrine, and Transplant Surgery, Medical University of Gdańsk; Gdańsk, Poland.
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Sledziński
Department of Nephrology, Transplantology, and Internal Diseases, Medical University of Gdańsk, Gdańsk, Poland.
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Rutkowski
D000293:Adolescent; D000328:Adult; D000368:Aged; D051799:Delayed Graft Function / Q000209:etiology; D005260:Female; D006084:Graft Rejection / Q000209:etiology; D006085:Graft Survival; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery* / Q000628:therapy; D016030:Kidney Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D014019:Tissue Donors; D016896:Treatment Outcome; D055815:Young Adult