Proposed objective visual system biomarkers for mild traumatic brain injury.
The challenge and search for objectively based biomarkers to assess for the presence of concussion/mild traumatic brain injury is a high priority for the military establishment. We present a documented overview of specific test areas and related targeted, high-yield, objectively based parameters that may be potential "vision biomarkers" for the detection of concussion/mild traumatic brain injury based on results from our laboratory and others, with emphasis on oculomotor aspects. These findings have military relevance with respect to the initial diagnosis in the battlefield and in the far-forward medical facilities, pre-/postdeployment issues, pre-/postvisual rehabilitation evaluation, fitness-for-duty assessment, and establishment of a return-to-duty timeline.
Department of Biological and Vision Sciences, SUNY State College of Optometry, 33 West 42nd Street, New York City, NY 10036.
Kenneth J
KJ
Ciuffreda
Department of Biological and Vision Sciences, SUNY State College of Optometry, 33 West 42nd Street, New York City, NY 10036.
Diana P
DP
Ludlam
Department of Biological and Vision Sciences, SUNY State College of Optometry, 33 West 42nd Street, New York City, NY 10036.
Preethi
P
Thiagarajan
Department of Biological and Vision Sciences, SUNY State College of Optometry, 33 West 42nd Street, New York City, NY 10036.
Naveen K
NK
Yadav
Department of Optometry, Womack Army Medical Center, Fort Bragg, NC 28310.
Jose
J
Capo-Aponte
D015415:Biomarkers / Q000032:analysis; D001924:Brain Concussion / Q000175:diagnosis*; D001930:Brain Injuries / Q000175:diagnosis*; D005074:Evoked Potentials, Visual / Q000502:physiology; D006801:Humans; D008889:Military Personnel; D009799:Ocular Physiological Phenomena; D014481:United States; D014786:Vision Disorders / Q000175:diagnosis; D014785:Vision, Ocular / Q000502:physiology*
D015415:Biomarkers