Vasopressin in cirrhosis and sepsis: physiology and clinical implications.
Arginine-vasopressin (AVP) is an important hormone in the regulation of plasma osmolality and blood volume/pressure. In clinical practice it is frequently used in the treatment of septic shock and decompensated cirrhosis. In this review the physiology of AVP and its analogues is presented. In addition the use of AVP in cirrhosis and sepsis is reviewed.
Department of Anesthesiology, College of Physicians and Surgeons of Columbia University New York, New York, NY, USA - gw72@cumc.columbia.edu.
G
G
Wagener
J
J
Bakker
D001127:Arginine Vasopressin / Q000502:physiology / Q000627:therapeutic use; D006801:Humans; D008102:Liver Circulation / Q000187:drug effects; D008103:Liver Cirrhosis / Q000188:drug therapy*; D018805:Sepsis / Q000188:drug therapy*; D012772:Shock, Septic / Q000188:drug therapy; D014662:Vasoconstrictor Agents / Q000627:therapeutic use*; D014667:Vasopressins / Q000502:physiology* / Q000627:therapeutic use*
D014662:Vasoconstrictor Agents; D014667:Vasopressins; D001127:Arginine Vasopressin