Device exchange in HeartMate II recipients: long-term outcomes and risk of thrombosis recurrence.
Successful long-term use of the HeartMate II (HM II) left ventricular assist device has become commonplace but may be complicated by mechanical failure, infection, or thrombosis necessitating device exchange (DE). A subcostal approach to device exchange with motor exchange only is less traumatic, but long-term outcomes have not been reported. A retrospective chart review of all patients who required HM II to HM II device exchange at our institution was conducted. Of the 232 HM II patients implanted between January 2008 and July 2013, 28 required 36 device exchanges during a follow-up of 33.72 ± 17.25 months. The Kaplan-Meier 1 year survival was 63% for sternotomy exchanges and 100% for subcostal exchanges. Twenty-one exchanges were performed for initial or recurring device thrombosis. Although there was no difference in the risk of subsequent thrombosis after subcostal versus sternotomy exchange, the overall risk of recurring device thrombosis after device exchange for the same was high (31%). HM II device exchange via the subcostal approach has excellent short- and long-term outcomes. Device exchange performed for thrombosis is associated with a high recurrence risk irrespective of surgical approach.
From the *Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, New York; †Division of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois; ‡Department of Surgery, Columbia University Medical Center, New York, New York; §Department of Surgery, University of Chicago, Chicago, Illinois; and ¶Department of Anesthesiology, Columbia University Medical Center, New York, New York.
Allison P
AP
Levin
Nir
N
Uriel
Hiroo
H
Takayama
Kanika P
KP
Mody
Takeyoshi
T
Ota
Melana
M
Yuzefpolskaya
Paolo C
PC
Colombo
Arthur R
AR
Garan
Marija
M
Dionizovik-Dimanovski
Robert N
RN
Sladen
Yoshifumi
Y
Naka
Ulrich P
UP
Jorde
D000328:Adult; D000368:Aged; D004868:Equipment Failure; D005260:Female; D006333:Heart Failure / Q000601:surgery*; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology; D012008:Recurrence; D012086:Reoperation / Q000009:adverse effects / Q000379:methods; D012189:Retrospective Studies; D012307:Risk Factors; D013927:Thrombosis / Q000209:etiology; D016896:Treatment Outcome