Intraocular metastasis of testicular natural killer T-cell lymphoma with diffuse retinal pigment epithelium changes.
OBJECTIVE
The purpose of this study was to report the first confirmed case of testicular natural killer T-cell lymphoma with bilateral intraocular metastasis.


METHODS
The author presents a chart review of a patient with testicular natural killer T-cell lymphoma metastasis to both eyes. This patient was treated with systemic chemotherapy, radiation, and intravitreal injections of methotrexate.


RESULTS
The author identified one case of a patient with the diagnosis of bilateral metastatic natural killer T-cell lymphoma with ocular involvement treated with intravitreal methotrexate. After treatment, the patient developed diffuse widespread retinal pigment epithelium alterations in giraffe-like patterns.


CONCLUSIONS
This represents a clinical case of a patient with primary testicular natural killer T-cell lymphoma and ocular metastasis with posttreatment retinal changes resembling bilateral diffuse uveal melanocytic proliferation.
From the Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut.
John J
JJ
Huang