[A case of definitive type 2 autoimmune pancreatitis diagnosed using endoscopic ultrasound-guided fine needle aspiration biopsy].
A 29-year-old man with ulcerative colitis presented to the hospital complaining of persistent back pain. Pancreatic enzymes and tumor markers were elevated; imaging showed diffuse narrowing of the main pancreatic duct associated with diffuse pancreatic enlargement. We therefore performed an endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) biopsy of the pancreas using a 19-gauge needle. Histopathology revealed interlobular fibrosis, neutrophil infiltration in the intralobular ducts and acini, and very few immunoglobulin G4-positive cells. The patient was diagnosed with type 2 autoimmune pancreatitis and started on oral steroids; subsequently, we observed an improvement in the pancreatic enlargement and duct narrowing. Histologically proven type 2 autoimmune pancreatitis is rare in Japan.
Department of Gastroenterology, Public Central Hospital of Matto Ishikawa.
Masaaki
M
Yano
Masashi
M
Nishikawa
Jun
J
Asai
Takeshi
T
Urabe
Hiroshi
H
Ito
D000328:Adult; D001327:Autoimmune Diseases / Q000188:drug therapy / Q000473:pathology*; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration; D006801:Humans; D008297:Male; D064847:Multimodal Imaging; D010195:Pancreatitis / Q000473:pathology*; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed