Delayed diagnosis of adult indolent systemic mastocytosis.
Systemic mastocytosis (SM) is a rare, heterogeneous disorder characterized by infiltration and accumulation of mast cells within multiple organs, most commonly the skin. Given the rarity of the disease and the fact that many of its symptoms are shared by more common disorders, a diagnosis may be delayed or hindered. These patients have an elevated risk of developing potentially life-threatening anaphylactoid reactions, thus underscoring the importance of keeping SM in mind as a differential diagnosis when a patient presents with chronic, itchy skin lesions and a history of multiple allergic reactions to bites, drugs, and anesthesia. We present a case illustrating that features of SM common to many disorders may hinder or delay its diagnosis.
Private Practice, Broenderslev, Denmark.
Carsten Sauer
CS
Mikkelsen
Private Practice, Broenderslev, Denmark.
Andrew
A
Nybo
Department of Dermatology, Aarhus University Hospital , Aarhus, Denmark.
Kristian Bakke
KB
Arvesen
Private Practice, Broenderslev, Denmark.
Johan
J
Holk-Poulsen
Darier's sign; indolent systemic masocytosis; mastocytosis; urticaria pigmentosa