Tractional retinal detachment after intravitreal injection of bevacizumab in proliferative diabetic retinopathy.
OBJECTIVE
To assess the short-term complications of a single dose of intravitreal bevacizumab in patients with proliferative diabetic retinopathy (PDR).


METHODS
Retrospective review of 343 patients with PDR who were treated with intravitreal injection of bevacizumab (2.5 mg/0.1 mL).


RESULTS
Five patients (1.45%) presented tractional retinal detachment 1 to 6 weeks (mean 3 weeks) after intravitreal injection. All cases underwent pars plana vitrectomy, removal of all epiretinal fibrovascular membranes, further endolaser panretinal photocoagulation, and silicone tamponade.


CONCLUSIONS
Tractional retinal detachment may occur in a short time post intravitreal injection of bevacizumab in patients with proliferative diabetic retinopathy with extensive areas of ischemia and fibrovascular proliferations, and may require prompt vitreoretinal surgery.
From the Retina Service, Asociacion Para Evitar la Ceguera, Hospital Dr. Luis Sánchez Bulnes, Coyoacan, México City, México.
Mitzy E
ME
Torres-Soriano
Elizabeth
E
Reyna-Castelán
Myrian
M
Hernández-Rojas
Gerardo
G
García-Aguirre
Verónica
V
Kon-Jara
José L
JL
Diaz-Rubio
José L
JL
Guerrero-Naranjo
Juan M
JM
Jiménez-Sierra
Hugo
H
Quiroz-Mercado