Neutrophilic dermatoses in a patient with collagenous colitis.
We report the case of a 75-year old woman with collagenous colitis who presented with erythematous and edematous plaques on the periorbital and eyelid regions, accompanied by oral ulcers. Histopathology showed a dermal neutrophilic infiltrate plus mild septal and lobular panniculitis with lymphocytes, neutrophils and eosinophils. Five years earlier she had presented a flare of papules and vesicles on the trunk, together with oral ulcers; a skin biopsy revealed a neutrophilic dermal infiltrate and Sweet's syndrome was diagnosed. Both the neutrophilic panniculitis and the Sweet's syndrome were accompanied by fever, malaise and diarrhea. Cutaneous and intestinal symptoms disappeared with corticoid therapy. The two types of neutrophilic dermatoses that appeared in periods of colitis activity suggest that intestinal and cutaneous manifestations may be related.
Department of Dermatology.
Didac
D
Barco
Department of Dermatology.
Maria A
MA
Barnadas
Department of Dermatology.
Esther
E
Roé
Department of Pathology.
Francisco J
FJ
Sancho
Department of Digestive Diseases, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Elena
E
Ricart
Department of Dermatology.
Agustín
A
Alomar
Sweet's syndrome; collagenous colitis.; inflammatory bowel disease; neutrophilic dermatoses; neutrophilic panniculitis