History of periodontitis as a risk factor for long-term survival of dental implants: a meta-analysis.
OBJECTIVE
The authors conducted a meta-analysis to determine the effect of a history of periodontitis on the long-term survival of dental implants.


METHODS
An electronic search of PubMed and a supplemental manual search were conducted. Studies published in English through March 2013 were included in the meta-analysis. Survival rates, success rates, periodontal status, types of periodontitis, most recent follow-up time, and other information were extracted and analyzed.


RESULTS
Thirteen studies involving 2,011 patients and 6,802 implants were included in the meta-analysis. The results revealed that a history of periodontitis, especially aggressive periodontitis, is associated with significantly higher risks of long-term implant failure versus a healthy periodontium (risk ratio [RR] = 1.03, 95% confidence interval [CI] = 1.02 to 1.04). Based on the limited number of included articles, a subgroup analysis showed that a history of periodontitis had no statistically significant effect on implant survival up to 100 months of follow-up (RR = 1.03, 95% CI = 0.99 to 1.06); however, it did significantly affect implant survival within a period of 101 to 200 months (RR = 1.03, 95% CI = 1.02 to 1.04). Some implant systems also significantly influenced the correlation between a history of periodontitis and implant survival.


CONCLUSIONS
Within the limitations of this meta-analysis, a history of periodontitis is estimated to be a statistical risk factor for the long-term survival of dental implants. This negative effect would be most evident in patients with aggressive periodontitis, severe periodontitis, or after a longer follow-up.
Xiujie
X
Wen
Rui
R
Liu
Gang
G
Li
Manjing
M
Deng
Luchuan
L
Liu
Xian-Tao
XT
Zeng
Xin
X
Nie
D010520:Aggressive Periodontitis / Q000150:complications; D015921:Dental Implants / Q000009:adverse effects; D019232:Dental Restoration Failure; D005500:Follow-Up Studies; D006801:Humans; D010512:Periodontal Index; D010518:Periodontitis / Q000145:classification / Q000150:complications*; D012307:Risk Factors; D016019:Survival Analysis
D015921:Dental Implants