Multifocal central serous chorioretinopathy with photoreceptor-retinal pigment epithelium diastasis in heritable pulmonary arterial hypertension.
OBJECTIVE
To report atypical central serous chorioretinopathy and choroidal thickening in a patient with heritable pulmonary arterial hypertension.


METHODS
A 40-year-old man with heritable pulmonary arterial hypertension presented with blurred vision in his left eye and was followed up for 1 year with clinical examination, enhanced depth optical coherence tomography, fluorescein and indocyanine green angiography, and fundus photography.


RESULTS
At presentation, atypical central serous chorioretinopathy with multiple retinal pigment epithelial detachments, a thick subfoveal choroid, and dilated choroidal vessels were seen in the patient's symptomatic left eye. After treatment for pulmonary hypertension, the serous detachments disappeared and choroidal thickness gradually decreased over a period of 4 weeks and remained unchanged at 13 months of follow-up.


CONCLUSIONS
Central serous chorioretinopathy and choroidal thickening that responded to treatment of pulmonary arterial hypertension suggest a pathophysiological link between pulmonary arterial hypertension and central serous chorioretinopathy, perhaps mediated by choroidal venous stasis.
*Department of Ophthalmology, Glostrup Hospital, Glostrup, Denmark; †Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark; and ‡Department of Cardiology, Pulmonary Vascular Program, Rigshospitalet, Copenhagen, Denmark.
Xiao Qiang
XQ
Li
Anders
A
Pryds
Jørn
J
Carlsen
Michael
M
Larsen
D000328:Adult; D056833:Central Serous Chorioretinopathy / Q000209:etiology*; D015862:Choroid Diseases / Q000209:etiology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications*; D008297:Male; D012163:Retinal Detachment / Q000209:etiology*; D055213:Retinal Pigment Epithelium / Q000473:pathology*