Histopathologic and immunohistological evaluation of anaplastic large cell lymphoma with Epstein-Barr virus in an orangutan (Pongo pygmaeus).
BACKGROUND
An 18-month-old female orangutan (Pongo pygmaeus) died after exhibiting fever, cough, and rapid breathing.


RESULTS
Based on serological, virological, histopathological and immunohistochemical examination, anaplastic large cell lymphoma was confirmed.


CONCLUSIONS
To the best of our knowledge, this is the first report of anaplastic large cell lymphoma associated with Epstein-Barr virus (EBV) in an orangutan.
Oral Cancer Research Institute, College of Dentistry, Yonsei University, Seoul, Republic of Korea.
Eun-Jung
EJ
Bak
Yeonsook
Y
Jho
Gye-Hyeong
GH
Woo
D000818:Animals; D000836:Animals, Zoo; D018420:Ape Diseases / Q000473:pathology / Q000821:virology*; D020031:Epstein-Barr Virus Infections / Q000473:pathology / Q000821:virology*; D017809:Fatal Outcome; D005260:Female; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D017728:Lymphoma, Large-Cell, Anaplastic / Q000473:pathology / Q000821:virology*; D011148:Pongo pygmaeus
anaplastic large cell lymphoma; herpes virus; lymph node; orangutan