Bilateral subinternal limiting membrane hemorrhage in benzene toxicity.
OBJECTIVE
To report the clinical and spectral domain optical coherence tomography findings in a patient with bilateral central vision loss and a history of exposure to polyamides.


METHODS
The clinical presentation of the patient was documented with color fundus photographs and spectral domain optical coherence tomography. The patient was a 20-year-old male factory worker with no medical history who was initially admitted for workup of hematologic malignancy due to petechiae and fevers.


RESULTS
Optical coherence tomography revealed bilateral hemorrhages in the subinternal limiting membrane space resembling Valsalva retinopathy. Complete blood count revealed pancytopenia and marked thrombocytopenia.


CONCLUSIONS
Heavy exposure to benzene, a byproduct of the polyamide-curing process, is known to cause aplastic anemia. Accompanying thrombocytopenia may increase the risk of spontaneous subinternal limiting membrane hemorrhage.
Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California.
Bryan K
BK
Hong
Anne E
AE
Baranano
Srinivas R
SR
Sadda
D001485:Basement Membrane / Q000473:pathology; D001554:Benzene / Q000633:toxicity*; D006801:Humans; D008297:Male; D016273:Occupational Exposure / Q000009:adverse effects; D010198:Pancytopenia / Q000139:chemically induced; D012166:Retinal Hemorrhage / Q000139:chemically induced*; D013921:Thrombocytopenia / Q000139:chemically induced; D041623:Tomography, Optical Coherence; D055815:Young Adult
D001554:Benzene