HTS for SMFS, organohalide respiration, new epigenetic mark, and a decoy receptor.
Each month, Chemistry & Biology Select highlights a selection of research reports from the recent literature. These highlights are a snapshot of interesting research done across the field of chemical biology. This month's Select highlights an on-chip platform for high-throughput force microscopy, a structural view of organohalide respiration, evidence that 5-hydroxymethylcytosine is an epigenetic mark, and use of a decoy receptor to thwart oncogene signaling.
D044503:5-Methylcytosine / Q000031:analogs & derivatives; D003596:Cytosine / Q000031:analogs & derivatives / Q000737:chemistry / Q000378:metabolism; D019175:DNA Methylation; D057890:Epigenomics; D057166:High-Throughput Screening Assays; D006846:Hydrocarbons, Halogenated / Q000737:chemistry / Q000378:metabolism*; D006867:Hydrolases / Q000378:metabolism; D046210:Microfluidic Analytical Techniques; D020411:Oligonucleotide Array Sequence Analysis; D053319:Tumor Necrosis Factor Decoy Receptors / Q000737:chemistry / Q000378:metabolism
D006846:Hydrocarbons, Halogenated; D053319:Tumor Necrosis Factor Decoy Receptors; C011865:5-hydroxymethylcytosine; D044503:5-Methylcytosine; D003596:Cytosine; D006867:Hydrolases