Sequential spectral domain optical coherence tomography imaging of an eye after successful removal of subfoveal perfluorcarbon liquid collection.
OBJECTIVE
To evaluate retinal restoration after subfoveal perfluorcarbon liquid (PFCL) bubble removal by means of autofluorescence, infrared, and spectral domain optical coherence tomography over 2 years of follow-up.


METHODS
A 62-year-old patient underwent two 23-gauge vitrectomies in attempt to remove subretinal PFCL retained under the fovea secondary to retinal detachment surgery in the left eye. We assessed best-corrected visual acuity, fundus biomicroscopy, retinal imaging by autofluorescence, infrared, and spectral domain optical coherence tomography at the first observation of retained PFCL, 1 day after the first attempt of PFCL removal, and 1, 30, 90, and 180 days, and 2 years after the second successful removal surgery.


RESULTS
The best-corrected visual acuity improved from 5 to 45 Early Treatment of Diabetic Retinopathy Study letters (1.0 to 0.2 logMAR units) at the end of follow-up. Spectral domain optical coherence tomography scans showed progressive reorganization of the outer limiting membrane and significant restoration of the inner/outer segment photoreceptors junction 2 years after surgery.


CONCLUSIONS
Subfoveal PFCL is believed to cause photoreceptor damage in some eyes, probably because of mechanical compression. Innovative methods of imaging such as spectral domain optical coherence tomography and confocal scanning laser ophthalmoscope with infrared and autofluorescence, allow early and clear detection of subfoveal retained PFCL, as well as careful follow-up and easy differential diagnosis. Surgical removal leads to prompt retinal morphologic restoration and functional improvement enduring over time.
*Department of Ophthalmology, Catholic University "Sacro Cuore-Policlinico A. Gemelli," Rome, Italy; and †"G. B. Bietti" Foundation, IRCCS, Rome, Italy.
Maria C
MC
Savastano
Lucia
L
Ziccardi
Gaetano
G
Zinzanella
Benedetto
B
Falsini
Angelo M
AM
Minnella
D005466:Fluorocarbons / Q000009:adverse effects*; D005584:Fovea Centralis; D006801:Humans; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000175:diagnosis / Q000601:surgery; D041623:Tomography, Optical Coherence / Q000379:methods*; D014821:Vitrectomy / Q000009:adverse effects*
D005466:Fluorocarbons