Leptomeningeal carcinomatosis associated with papillary renal cell carcinoma.
Leptomeningeal carcinomatosis (LMC), or neoplastic meningitis, occurs in about 5-20% of patients with metastatic cancer, depending on the type of the primary malignancy and kind of treatment received. The association of LMC with renal cell carcinoma (RCC) is a rare entity, and only two cases of papillary renal cell cancer with leptomeningeal metastasis have been reported. Leptomeningeal spread usually confers a poor prognosis despite the use of modern treatment strategies as compared to patients with extracranial metastases. We report a case of papillary RCC, a less common type of RCC presenting with LMC.
Department of Haematology and Oncology, Allegheny General Hospital, Pittsburgh, PA 15212, USA.
Abhishek
A
Chilkulwar
Department of Internal Medicine, Mount Sinai Hospital Medical Centre, Chicago, Illinois 60608, USA.
Ramya
R
Pottimutyapu
Department of Internal Medicine, Mount Sinai Hospital Medical Centre, Chicago, Illinois 60608, USA.
Fawng
F
Wu
Department of Medicine, S.V.S Medical College, Mahbub Nagar, Telangana 509001, India.
Keerthi R
KR
Padooru
Houston Methodist Cancer Centre, 6445 Main St, Houston, TX 77030, USA.
Sai Ravi
SR
Pingali
Department of Internal Medicine, Mount Sinai Hospital Medical Centre, Chicago, Illinois 60608, USA.
Mohammed
M
Kassem
leptomeningeal carcinomatosis; leptomeningeal metastasis; neoplastic meningitis; papillary renal cell carcinoma