Oral glucose solution to alleviate pain induced by intramuscular injections in preterm infants.
OBJECTIVE
The purpose was to assess the effectiveness of 5% oral glucose solution in reducing pain in preterm infants during intramuscular injection.


METHODS
We conducted a prospective, randomized, controlled, unblinded trial to investigate the effect of glucose solution on the pain of intramuscular injection in preterm infants (N = 80).


RESULTS
Infants who received oral glucose had significantly lower pain scores (p < .001), less crying time (p < .001), higher oxygen saturation (p < .001), and lower heart rate after compared with during the procedure (p = .02).


CONCLUSIONS
Our results suggest that oral glucose, even if used in the lowest dose, may have a pain-relieving effect in preterm infants if administered pre-procedure.
Katip Çelebi University, School of Nursing, İzmir, Turkey.
Derya
D
Uzelli
Ülkü
Ü
Yapucu Güneş
D000284:Administration, Oral; D005260:Female; D005947:Glucose / Q000008:administration & dosage*; D006801:Humans; D007224:Infant Care / Q000379:methods; D007231:Infant, Newborn; D007234:Infant, Premature; D007273:Injections, Intramuscular / Q000009:adverse effects; D008297:Male; D017283:Neonatal Nursing / Q000379:methods; D010146:Pain / Q000209:etiology / Q000517:prevention & control*; D010147:Pain Measurement / Q000379:methods*; D011446:Prospective Studies; D012016:Reference Values; D012996:Solutions / Q000008:administration & dosage; D016896:Treatment Outcome
D012996:Solutions; D005947:Glucose
Glucose; intramuscular injection; pain intensity; preterm infant