INTERFERON-β-ASSOCIATED RETINOPATHY.
BACKGROUND
Interferon-associated retinopathy is a rare complication of interferon treatment. It has been well described with the use of interferon-α.


METHODS
This study reports a retrospective case series of interferon-β-associated retinopathy in three patients that were being treated for multiple sclerosis.


RESULTS
All cases were characterized by cotton-wool spots or peripheral microaneurysms. One central retinal artery occlusion was observed associated with interferon-β treatment. Findings improved spontaneously in two of three cases; all three patients elected to continue interferon treatment.


CONCLUSIONS
Patients being treated with interferon-β should have periodic fundus examinations to determine if they have evidence of interferon-associated retinopathy.
From *the Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota; †Iowa Retina Consultants, West Des Moines, Iowa; and ‡the Department of Ophthalmology, Northwestern University, Chicago, Illinois.
Javier S
JS
Martinez de Aragon
Jose S
JS
Pulido
Christopher L
CL
Haupert
Christopher F
CF
Blodi
Jared S
JS
Nielsen
Lee M
LM
Jampol