The reaction of dimethylalkynylaluminum reagents with trimethylsilyldiazomethane: original reactivity leading to new α-silylated alkynyl hydrazones.
Trimethylsilyl (TMS) diazomethane does not react as a homologating reagent but as a C-electrophilic species with dimethylalkynylaluminum reagents. This unprecedented reactivity enables a simple access to unusual α-silylated alkynyl hydrazones.
Laboratoire de Chimie et Biochimie et Pharmacologiques et Toxicologiques, UMR 8601 CNRS-Université Paris Descartes Faculté des Sciences Fondamentales et Biomédicales, 45 rue des Saints Pères, 75006 Paris, France.
Rahul
R
Kumar
Laboratoire de Chimie et Biochimie et Pharmacologiques et Toxicologiques, UMR 8601 CNRS-Université Paris Descartes Faculté des Sciences Fondamentales et Biomédicales, 45 rue des Saints Pères, 75006 Paris, France.
Serge
S
Turcaud
Laboratoire de Chimie et Biochimie et Pharmacologiques et Toxicologiques, UMR 8601 CNRS-Université Paris Descartes Faculté des Sciences Fondamentales et Biomédicales, 45 rue des Saints Pères, 75006 Paris, France.
Laurent
L
Micouin
D000480:Alkynes / Q000138:chemical synthesis* / Q000737:chemistry*; D000535:Aluminum / Q000737:chemistry*; D002384:Catalysis; D003978:Diazomethane / Q000031:analogs & derivatives* / Q000737:chemistry; D006835:Hydrazones / Q000138:chemical synthesis*; D007202:Indicators and Reagents / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry*; D013237:Stereoisomerism; D014297:Trimethylsilyl Compounds / Q000737:chemistry*
D000480:Alkynes; D006835:Hydrazones; D007202:Indicators and Reagents; D009942:Organometallic Compounds; D012821:Silanes; D014297:Trimethylsilyl Compounds; D003978:Diazomethane; D000535:Aluminum; C060070:trimethylsilyldiazomethane