Whole prostate volume and shape changes with the use of an inflatable and flexible endorectal coil.
Purpose. To determine to what extent an inflatable endorectal coil (ERC) affects whole prostate (WP) volume and shape during prostate MRI. Materials and Methods. 79 consecutive patients underwent T2W MRI at 3T first with a 6-channel surface coil and then with the combination of a 16-channel surface coil and ERC in the same imaging session. WP volume was assessed by manually contouring the prostate in each T2W axial slice. PSA density was also calculated. The maximum anterior-posterior (AP), left-right (LR), and craniocaudal (CC) prostate dimensions were measured. Changes in WP prostate volume, PSA density, and prostate dimensions were then evaluated. Results. In 79 patients, use of an ERC yielded no significant change in whole prostate volume (0.6 ± 5.7%, P = 0.270) and PSA density (-0.2 ± 5.6%, P = 0.768). However, use of an ERC significantly decreased the AP dimension of the prostate by -8.6 ± 7.8% (P < 0.001), increased LR dimension by 4.5 ± 5.8% (P < 0.001), and increased the CC dimension by 8.8 ± 6.9% (P < 0.001). Conclusion. Use of an ERC in prostate MRI results in the shape deformation of the prostate gland with no significant change in the volume of the prostate measured on T2W MRI. Therefore, WP volumes calculated on ERC MRI can be reliably used in clinical workflow.
Molecular Imaging Program, NCI, NIH, Bethesda, MD 20892, USA ; George Washington University, Washington, DC 20052, USA.
Murat
0000-0001-8976-4127
M
Osman
Department of Radiology, Nephrology Center, Mansoura University, Mansoura 35516, Egypt.
Haytham
H
Shebel
Molecular Imaging Program, NCI, NIH, Bethesda, MD 20892, USA.
Sandeep
0000-0002-8398-2016
S
Sankineni
Molecular Imaging Program, NCI, NIH, Bethesda, MD 20892, USA ; Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Marcelino L
ML
Bernardo
Molecular Imaging Program, NCI, NIH, Bethesda, MD 20892, USA.
Dagane
D
Daar
Center for Interventional Oncology, NIH, Bethesda, MD 20892, USA.
Bradford J
BJ
Wood
Urologic Oncology Branch, NCI, NIH, Bethesda, MD 20892, USA.
Peter A
PA
Pinto
Molecular Imaging Program, NCI, NIH, Bethesda, MD 20892, USA.
Peter L
PL
Choyke
Molecular Imaging Program, NCI, NIH, Bethesda, MD 20892, USA.
Baris
B
Turkbey
Molecular Imaging Program, NCI, NIH, Bethesda, MD 20892, USA ; Philips Research North America, Briarcliff Manor, NY 10510, USA.
Harsh K
HK
Agarwal