Green synthesis of phosphoryl-2-oxo-2H-pyran via three component reaction of trialkyl phosphites.
An effective one-pot synthesis of dialkoxyphosphoryl-2-oxo-2H-pyran derivatives by three-component reaction of alky bromides and dialkyl acetylenedicarboxylates in the presence of trialkyl phosphite is described. The reactions were performed under solvent-free conditions at 50°C and neutral conditions and provided good yields of products.
Zinatossadat
Z
Hossaini
Fatemeh
F
Sheikholeslami-Farahani
Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran. zshossaini@yahoo.com.
Faramarz
F
Rostami-Charati
D000114:Acetylene / Q000031:analogs & derivatives / Q000737:chemistry*; D003998:Dicarboxylic Acids / Q000737:chemistry*; D055772:Green Chemistry Technology; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D015394:Molecular Structure; D063065:Organophosphonates / Q000138:chemical synthesis* / Q000737:chemistry; D017905:Phosphites / Q000737:chemistry*; D011753:Pyrones / Q000138:chemical synthesis* / Q000737:chemistry
D003998:Dicarboxylic Acids; D006842:Hydrocarbons, Brominated; D063065:Organophosphonates; D017905:Phosphites; D011753:Pyrones; D000114:Acetylene