Self-organizing behaviour of glycosteroidal bolaphiles: insights into lipidic microsegregation.
In this article we describe work on the synthesis of bolaphile biomimics composed of glucose head groups and steroidal units linked together by a methylene chain of varying length. The condensed phases formed by self-organization of the products as a function of temperature were characterized by differential scanning calorimetry and thermal polarized light microscopy. The results of these studies show that the thermal stabilities of the lamellar mesophases formed vary linearly as a function of increasing aliphatic composition, which reflects a linear hydrophobic-hydrophilic balance with respect to transition temperatures.
INSA Lyon, ICBMS, Bâtiment J. Verne, 20 av A. Einstein, F 69621 Villeurbanne, France. yves.queneau@insa-lyon.fr.
R
R
Xu
F
F
Ali-Rachedi
N M
NM
Xavier
S
S
Chambert
F
F
Ferkous
Y
Y
Queneau
S J
SJ
Cowling
E J
EJ
Davis
J W
JW
Goodby
D040761:Biomimetic Materials / Q000737:chemistry*; D002152:Calorimetry, Differential Scanning; D006017:Glycolipids / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D008051:Lipid Bilayers / Q000737:chemistry; D009005:Monosaccharides / Q000138:chemical synthesis; D044367:Phase Transition; D011789:Quantum Theory; D012992:Solanine / Q000737:chemistry; D013256:Steroids / Q000737:chemistry*; D013696:Temperature; D013816:Thermodynamics
D006017:Glycolipids; D008051:Lipid Bilayers; D009005:Monosaccharides; D013256:Steroids; C514919:alpha-solanine; D012992:Solanine