Transient retinal venous and arterial occlusive events in a case of sneddon syndrome.
OBJECTIVE
We report a case with venous and arterial occlusive events in Sneddon syndrome and describe the accompanying fluorescein angiographic findings.


METHODS
Observational case report.


RESULTS
This 27-year-old white woman developed acute visual loss and a central scotoma in her right eye in consequence of a central retinal vein occlusion and, 2 years later, a paracentral scotoma in her left eye in consequence of an incomplete branch retinal artery occlusion. Fluorescein angiography revealed an unusual laminar hyperfluorescence downstream to the arterial obstruction. Patient became seropositive for anticardiolipin antibodies in the course of the 2 years. Eventually, the ocular together with neurologic and cardiac manifestations led to the diagnosis of Sneddon syndrome.


CONCLUSIONS
Sneddon syndrome should be considered in any ocular vascular occlusive event under the age of 50 years. In addition, this case reports for the first time unusual fluorescein angiographic findings of incomplete branch retinal arterial occlusions, possibly associated with endothelial damage in Sneddon syndrome.
Department of Ophthalmology, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands.
Jan P
JP
Witmer
Hans
H
van Vreeswijk
Antonella N
AN
Witmer