title: [Thymoma with extensive coagulative necrosis and high serum level of CYFRA 21-1; report of a case].
abstract: A 73-year-old woman complained of right chest discomfort. Chest X-ray during the follow-up for rheumatoid arthritis showed a mediastinal tumor. Chest computed tomography (CT) and magnetic resonance imaging (MRI) showed a 65-mm tumor in the right anterior mediastinum. A blood test showed high serum levels of CYFRA 21-1(29.8 ng/ml), white blood cells( WBC 10,800/µl), and C-reactive protein(CRP 16.1 mg/dl). Subsequently, inflammatory reactions improved, and the thymic tumor was resected. Histopathologically, the tumor was a type B2 thymoma with extensive coagulative necrosis. After resection, the serum CYFRA 21-1 level returned to the normal range.
authors.affiliation: Division of Chest Surgery, Showa University School of Medicine, Tokyo, Japan.
authors.forename: Naoya
authors.initials: N
authors.lastname: Himuro
authors.forename: Takao
authors.initials: T
authors.lastname: Minakata
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Oshima
authors.forename: Yuri
authors.initials: Y
authors.lastname: Tomita
authors.forename: Daisuke
authors.initials: D
authors.lastname: Kataoka
authors.forename: Mitsutaka
authors.initials: M
authors.lastname: Kadokura
mesh_terms: D000368:Aged; D000951:Antigens, Neoplasm / Q000097:blood*; D005260:Female; D006801:Humans; D053539:Keratin-19 / Q000097:blood*; D009336:Necrosis; D013945:Thymoma / Q000097:blood / Q000473:pathology / Q000601:surgery*; D013953:Thymus Neoplasms / Q000097:blood / Q000473:pathology / Q000601:surgery*; D014057:Tomography, X-Ray Computed
chemical_list: D000951:Antigens, Neoplasm; D053539:Keratin-19; C102012:antigen CYFRA21.1