title: Trachelectomy during pregnancy: what has experience taught us?
abstract: The treatment of early stage cervical malignancy in a pregnant patient remains a challenge. We report the successful application of a vaginal radical trachelectomy (VRT) during pregnancy to treat a patient diagnosed with early stage cervical cancer and subsequently review the published work. A 22-year-old female diagnosed at the gestational age of 17 weeks with International Federation of Gynecology and Obstetrics stage IB1 squamous cell cervical carcinoma was treated with VRT at 19(+5) weeks. At 36 weeks, the patient underwent a scheduled cesarean section. A healthy male infant was delivered with a weight of 2795 g. After 13 months of follow-up, the patient is doing well with no evidence of recurrent disease.
authors.affiliation: Division of Surgery and Cancer, Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Hospital Campus, London, UK.
authors.forename: Srdjan
authors.initials: S
authors.lastname: Saso
authors.forename: Renata
authors.initials: R
authors.lastname: Sawyer
authors.forename: Nicole M
authors.initials: NM
authors.lastname: O'Neill
authors.forename: Menelaos
authors.initials: M
authors.lastname: Tzafetas
authors.forename: Ahmed
authors.initials: A
authors.lastname: Sayasneh
authors.forename: Ali Hassan
authors.initials: AH
authors.lastname: Hamed
authors.forename: Freya
authors.initials: F
authors.lastname: Elliott
authors.forename: Meen-Yau
authors.initials: MY
authors.lastname: Thum
authors.forename: Sadaf
authors.initials: S
authors.lastname: Ghaem-Maghami
authors.forename: Men-Jean
authors.initials: MJ
authors.lastname: Lee
authors.forename: J Richard
authors.initials: JR
authors.lastname: Smith
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Del Priore
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology / Q000601:surgery*; D011256:Pregnancy Outcome; D000069339:Trachelectomy; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*; D055815:Young Adult
keywords: cervical cancer; fertility; pregnancy; trachelectomy