title: [Deep brain stimulation using simultaneous stereotactic electrode placement: an alternative to conventional functional stereotaxy?].
abstract: BACKGROUND
  Deep brain stimulation (DBS) has become a reliable method in the treatment of movement disorders, e.g. idiopathic Parkinson's disease (IPD) and is technically based on stereotaxy. The Starfix® platform is a new type of stereotactic frame that allows an individualized and patient-optimized therapeutic regimen in IPD.
  
  
  OBJECTIVE
  The aim of this study was to retrospectively compare the outcomes of IPD patients who underwent surgery with the use of conventional stereotactic frames (31 patients) to those who underwent implantation of DBS with the use of Starfix® frames (29 patients).
  
  
  METHODS
  Surgery time, the unified Parkinson's disease rating scale III (UPDRS/III) score, L-dopa and L-dopa equivalent doses (LED) were compared prior to surgery as well as 4 weeks, 12 weeks, 6 months and 1 year postoperatively.
  
  
  RESULTS
  The IPD-related symptoms improved significantly in both groups with respect to the UPDRS III score (conventional 69.6% vs. 72.4% Starfix®). After surgery significant reductions of L-dopa and LED were seen in both groups. Inherent advantages of the Starfix® platform included simultaneous positioning of the stimulating electrodes and a significant reduction in surgical time.
  
  
  CONCLUSIONS
  In summary, both stereotactic procedures are reliable and safe procedures for the placement of stimulating electrodes as well as the stimulation effect achieved. The logistical uncoupling of presurgical planning from surgical therapy emphasizes the benefits of the individualized stereotactic procedure.
authors.affiliation: Klinik und Poliklinik für Neurochirurgie, Universitätsklinikum Leipzig, Liebigstr. 20, 04103, Leipzig, Deutschland.
authors.forename: C
authors.initials: C
authors.lastname: Matzke
authors.forename: N
authors.initials: N
authors.lastname: Hammer
authors.forename: D
authors.initials: D
authors.lastname: Weise
authors.forename: D
authors.initials: D
authors.lastname: Lindner
authors.forename: D
authors.initials: D
authors.lastname: Fritzsch
authors.forename: J
authors.initials: J
authors.lastname: Classen
authors.forename: J
authors.initials: J
authors.lastname: Meixensberger
authors.forename: D
authors.initials: D
authors.lastname: Winkler
mesh_terms: D000328:Adult; D000368:Aged; D046690:Deep Brain Stimulation / Q000295:instrumentation* / Q000379:methods*; D004567:Electrodes, Implanted; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009069:Movement Disorders / Q000209:etiology / Q000628:therapy*; D010300:Parkinson Disease / Q000150:complications / Q000628:therapy*; D019919:Prosthesis Implantation / Q000295:instrumentation* / Q000379:methods; D013238:Stereotaxic Techniques / Q000295:instrumentation*; D016896:Treatment Outcome