title: MAX-ing out MYC: a novel small molecule inhibitor against MYC-dependent tumors.
authors.affiliation: Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (IICC, GY, DT); Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (GY).
authors.forename: Iok In Christine
authors.initials: II
authors.lastname: Chio
authors.affiliation: Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (IICC, GY, DT); Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (GY).
authors.forename: Georgi
authors.initials: G
authors.lastname: Yordanov
authors.affiliation: Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (IICC, GY, DT); Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (GY). dtuveson@cshl.edu.
authors.forename: David
authors.initials: D
authors.lastname: Tuveson
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D021441:Carcinoma, Pancreatic Ductal / Q000188:drug therapy* / Q000235:genetics*; D008297:Male; D010190:Pancreatic Neoplasms / Q000188:drug therapy* / Q000235:genetics*; D016271:Proto-Oncogene Proteins c-myc / Q000037:antagonists & inhibitors*; D016283:Proto-Oncogene Proteins p21(ras) / Q000235:genetics*; D013844:Thiazoles / Q000494:pharmacology*
chemical_list: C524814:5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one; D000970:Antineoplastic Agents; C489428:Myc protein, mouse; D016271:Proto-Oncogene Proteins c-myc; D013844:Thiazoles; C495971:Hras protein, mouse; D016283:Proto-Oncogene Proteins p21(ras)