title: Duplicated pelvic floor musculature and diastematomyelia in a cloacal exstrophy patient.
abstract: Cloacal exstrophy is the most severe and rare form of the exstrophy-epispadias complex, presenting with exposed bladder halves extruding through an abdominal wall defect and variable genitourinary, gastrointestinal, musculoskeletal, and neurological defects. The authors report magnetic resonance imaging findings of a neurologically-intact, 24-month-old female with cloacal exstrophy who presented with anterior spinal dysraphism and diastematomyelia and duplicate pelvic floor musculature. The constellation of defects suggests a common genetic, biochemical, and embryological origin for duplication of the bladder, spinal cord, and pelvic floor muscles occurring in the fourth week of gestation.
authors.affiliation: Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins Medical Institution, Baltimore, MD, USA.
authors.forename: Brian M
authors.initials: BM
authors.lastname: Inouye
authors.affiliation: Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins Medical Institution, Baltimore, MD, USA.
authors.forename: Ali
authors.initials: A
authors.lastname: Tourchi
authors.affiliation: Division of Pediatric Urology, Akron Children's Hospital, Northeast Ohio Medical University, Akron, OH, USA.
authors.forename: Eric Z
authors.initials: EZ
authors.lastname: Massanyi
authors.affiliation: Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins Medical Institution, Baltimore, MD, USA.
authors.forename: John P
authors.initials: JP
authors.lastname: Gearhart
authors.affiliation: Division of Pediatric Radiology and Section of Pediatric Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: Aylin
authors.initials: A
authors.lastname: Tekes
mesh_terms: D002675:Child, Preschool; D002988:Cloaca / Q000002:abnormalities*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009436:Neural Tube Defects / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging; D010384:Pelvic Bones / Q000002:abnormalities; D017773:Pelvic Floor / Q000002:abnormalities* / Q000000981:diagnostic imaging; D011859:Radiography
keywords: Cloacal Exstrophy; Diastematomyelia; Duplicated Pelvic Floor; Etiology; Exstrophy-Epispadias Complex; Spinal Dysraphism