title: Arteriosclerosis can predict hypotension during anesthesia induction in patients 40 years and older.
abstract: OBJECTIVE
  To identify the factors that predict blood pressure (BP) changes during induction of general anesthesia, and the relationship between the level of arteriosclerosis and BP changes during anesthesia induction.
  
  
  METHODS
  Prospective, case-control observational study.
  
  
  METHODS
  Operating room of a university hospital.
  
  
  METHODS
  Seventy-two patients who received general anesthesia for oral and maxillofacial surgery.
  
  
  METHODS
  Brachial-ankle pulse wave velocity (baPWV) and central BP were measured. The primary variable was the parameters affecting BP changes during the induction of general anesthesia. For additional analyses, the parameters were compared between high and low PWV groups (1606 cm/s was the cutoff value of baPWV). To measure the relationships between the parameters and BP changes, bivariate and multiple linear regression analyses were performed.
  
  
  RESULTS
  Seventy-two patients (including 41 men) with a mean age of 61.7 years and a median baPWV value of 1606 cm/s were evaluated. Significantly higher values for age, central BP, preoperative systolic BP (SBP), amount of decrease in SBP and diastolic BP, and number of patients with diabetes mellitus (DM) and hypertension were observed in the high PWV group. Multiple linear regression analysis demonstrated that age, baPWV, and DM were factors independently associated with the amount of decrease in SBP.
  
  
  CONCLUSIONS
  In patients 40 years and older, age, baPWV, and DM are thought to be effective predictors of the amount of decrease in SBP during induction of general anesthesia.
authors.affiliation: Special Patient Oral Care Unit, Kyushu University Hospital, 3-1-1, Maidashi, Higashi-ku, Fukuoka, Fukuoka 812-8582, Japan; Department of Dental Anesthesiology, Graduate School of Dentistry, Osaka University, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: ysn-mori@dent.kyushu-u.ac.jp.
authors.forename: Yoshinari
authors.initials: Y
authors.lastname: Morimoto
authors.affiliation: Department of Dental Anesthesiology, Graduate School of Dentistry, Osaka University, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Yamagata
authors.affiliation: Department of Dental Anesthesiology, Graduate School of Dentistry, Osaka University, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hanamoto
authors.affiliation: Department of Dental Anesthesiology, Graduate School of Dentistry, Osaka University, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Aiji
authors.initials: A
authors.lastname: Boku
authors.affiliation: Department of Dental Anesthesiology, Graduate School of Dentistry, Osaka University, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Chiho
authors.initials: C
authors.lastname: Kudo
authors.affiliation: Department of Dental Anesthesiology, Graduate School of Dentistry, Osaka University, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Chizuko
authors.initials: C
authors.lastname: Yokoe
authors.affiliation: Department of Dental Anesthesiology, Graduate School of Dentistry, Osaka University, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Mitsutaka
authors.initials: M
authors.lastname: Sugimura
authors.affiliation: Department of Dental Anesthesiology, Graduate School of Dentistry, Osaka University, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Niwa
keywords: Age; Arteriosclerosis; Brachial-ankle pulse wave velocity (baPWV); Diabetes mellitus; General anesthesia; Hypotension