title: A pediatric case of T-cell prolymphocytic leukemia.
abstract: T-cell Prolymphocytic Leukemia (T-PLL) is a rare entity, and to date has never been reported in children. Here, we describe the first pediatric case of T-PLL in a 16-year old male and review his clinical course through treatment. He underwent therapy with alemtuzumab and pentostatin, which was successful in inducing initial remission. He then underwent an allogeneic matched sibling stem cell transplant following a myeloablative conditioning regimen and remains disease-free 1.5 years after diagnosis.
authors.affiliation: Department of Pediatrics, Division of Hematology-Oncology and Stem Cell Transplantation, Lucile Packard Children's Hospital at Stanford University, Palo Alto, California.
authors.forename: Bryan
authors.initials: B
authors.lastname: Mitton
authors.forename: Steven
authors.initials: S
authors.lastname: Coutre
authors.forename: Jennifer
authors.initials: J
authors.lastname: Willert
authors.forename: Krysta
authors.initials: K
authors.lastname: Schlis
authors.forename: Matthew
authors.initials: M
authors.lastname: Porteus
authors.forename: Sandhya
authors.initials: S
authors.lastname: Kharbanda
authors.forename: Rajni
authors.initials: R
authors.lastname: Agarwal-Hashmi
mesh_terms: D000293:Adolescent; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D015461:Leukemia, Prolymphocytic, T-Cell / Q000628:therapy*; D008297:Male; D014184:Transplantation, Homologous
keywords: T-cell prolymphocytic leukemia; bone marrow transplant; pediatrics