title: BRD control: tying it all together to deliver value to the industry.
abstract: Pasteur described an organism causing fowl cholera in 1880. In 134 years we have progressed from crude vaccines for Pasteurella, to some refined vaccines, to a name change (Mannheimia), to autogenous vaccines (back to crude). In the last 25-30 years, we have attempted to mitigate the problem of bovine respiratory disease with antimicrobials and subsequently have a high incidence of multi-drug resistance. All of these attempts have resulted in little if any improvement in morbidity/mortality. Is it time to focus on the animal's response or lack of response to infectious pressure? Instead of focusing on the 10-50% morbid cattle should we focus on the 50-90% that are not compromised and determine why they stay healthy under the same environmental conditions?
authors.affiliation: Veterinary Research and Consulting Services,LLC,Greeley,Colorado,USA.
authors.forename: Delbert G
authors.initials: DG
authors.lastname: Miles
authors.affiliation: Veterinary Research and Consulting Services,LLC,Greeley,Colorado,USA.
authors.forename: Karen C
authors.initials: KC
authors.lastname: Rogers
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D048090:Bovine Respiratory Disease Complex / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control*; D002417:Cattle; D004352:Drug Resistance, Microbial; D010326:Pasteurella Infections; D012766:Pasteurellosis, Pneumonic; D014612:Vaccines
chemical_list: D000900:Anti-Bacterial Agents; D014612:Vaccines