title: Cation-π interactions in iminium ion activation: correlating quadrupole moment & enantioselectivity.
abstract: A linear correlation between quadrupole moment (Qzz) and enantioselectivity (es) advocates the notion that a cation-π interaction is a contributing factor in the addition of uncharged nucleophiles to iminium salts derived from MacMillan's 1st generation catalyst. The quadrupole moment of the aryl shielding group is a useful qualitative parameter for predicting selectivity (Qzz < 0 → high es).
authors.affiliation: Organisch Chemisches Institut, and Excellence Cluster EXC 1003, Cells in Motion, Westfälische Wilhelms-Universität Münster, Corrensstrasse 40, Münster, Germany. ryan.gilmour@uni-muenster.de.
authors.forename: M C
authors.initials: MC
authors.lastname: Holland
authors.forename: J B
authors.initials: JB
authors.lastname: Metternich
authors.forename: C
authors.initials: C
authors.lastname: Mück-Lichtenfeld
authors.forename: R
authors.initials: R
authors.lastname: Gilmour