title: Mitochondrial fusion through membrane automata.
abstract: Studies have shown that malfunctions in mitochondrial processes can be blamed for diseases. However, the mechanism behind these operations is yet not sufficiently clear. In this work we present a novel approach to describe a biomolecular model for mitochondrial fusion using notions from the membrane computing. We use a case study defined in BioAmbient calculus and we show how to translate it in terms of a P automata variant. We combine brane calculi with (mem)brane automata to produce a new scheme capable of describing simple, realistic models. We propose the further use of similar methods and the test of other biomolecular models with the same behaviour.
authors.affiliation: Department of Informatics, Ionian University, Corfu, Greece, kgiann@ionio.gr.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Giannakis
authors.forename: Theodore
authors.initials: T
authors.lastname: Andronikos
mesh_terms: D000818:Animals; D019295:Computational Biology / Q000379:methods*; D006801:Humans; D008561:Membrane Fusion / Q000502:physiology*; D063154:Mitochondrial Dynamics / Q000502:physiology*; D051336:Mitochondrial Membranes / Q000502:physiology*; D024101:Mitochondrial Proteins / Q000502:physiology; D008954:Models, Biological
chemical_list: D024101:Mitochondrial Proteins