title: Transcatheter Arterial Chemoembolization and Chemotherapy plus Sorafenib in a Large Hepatocellular Carcinoma with Arterioportal Shunt.
abstract: Introduction. Arterioportal shunts (APS) are sometimes encountered in patients with hepatocellular carcinoma (HCC) and associated with poor prognosis. The management of HCC with APS is a challenge so far. Case Presentations. We report here in detail a 37-year-old man who was diagnosed as an advanced HCC accompanied with severe APS and treated by two sessions of transcatheter arterial chemoembolization (TACE) and three sessions of transcatheter arterial chemotherapy (TAC) plus sorafenib therapy. The tumor shrinks were revealed continuously during 152 days after the diagnosis. Although tumor progress emerged at 209 days after the diagnosis, the patient remarkably achieved 366-day survival. Discussion. TACE plus sorafenib may be a promising treatment for advanced HCC accompanied with APS. Prospective case-control studies should be advocated to evaluate the combination of TACE, TAC, and sorafenib in the management of HCC with APS.
authors.affiliation: Department of Radiology, Jiangsu Cancer Hospital and Cancer Hospital of Nanjing Medical University (NMU), 42 Baiziting Road, Nanjing 210009, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Chen
authors.affiliation: Department of Radiology, Jiangsu Cancer Hospital and Cancer Hospital of Nanjing Medical University (NMU), 42 Baiziting Road, Nanjing 210009, China.
authors.forename: Shixi
authors.initials: S
authors.lastname: Chen
authors.affiliation: Department of Radiology, Jiangsu Cancer Hospital and Cancer Hospital of Nanjing Medical University (NMU), 42 Baiziting Road, Nanjing 210009, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Xi
authors.affiliation: Department of Radiology, Jiangsu Cancer Hospital and Cancer Hospital of Nanjing Medical University (NMU), 42 Baiziting Road, Nanjing 210009, China.
authors.forename: Bei
authors.initials: B
authors.lastname: Wu
authors.affiliation: Department of Radiology, Jiangsu Cancer Hospital and Cancer Hospital of Nanjing Medical University (NMU), 42 Baiziting Road, Nanjing 210009, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Yu
authors.affiliation: Department of Radiology, Jiangsu Cancer Hospital and Cancer Hospital of Nanjing Medical University (NMU), 42 Baiziting Road, Nanjing 210009, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Gao