title: Relationship Between the Hypersensitive c-Reactive Protein (hs-CRP) Level and the Prognosis of Acute Brainstem Infarction.
abstract: The objective of this study is to explore the relationship between the hypersensitive c-reactive protein (hs-CRP) level and the prognosis of acute brainstem infarction. Serum levels of hs-CRP were measured in 68 patients with acute brainstem infarction 72 h after disease onset. The hs-CRP levels in the U.S. National Institutes of Health Stroke Scale (NIHSS) score group and in the modified RANKIN scale (mRS) score group were compared. The independent risk factors of brainstem infarction were analyzed using Logistic binary regression. The hs-CRP level was significantly higher in the group with NIHSS >5 compared with the one with NIHSS ≤ 5 (P = 0.004). In the group with mRS > 2, the age, smoking history, and blood glucose level were significantly higher than those in the group with mRS ≤ 2 (P < 0.05), whereas the hs-CRP level was significantly higher (P = 0.001). Age and hs-CRP level were the independent prognostic factors of the brainstem infarction. The serum hs-CRP level is closely related with the severity and prognosis of brainstem infarction, and is an independent risk factor of acute brainstem infarction.
authors.affiliation: Department of Neurology, Xuzhou Central Hospital, Xuzhou, 221009, Jiangsu, China. baogaozx@163.com.
authors.forename: Xia
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Department of Neurology, Xuzhou Central Hospital, Xuzhou, 221009, Jiangsu, China.
authors.forename: Wen-Juan
authors.initials: WJ
authors.lastname: Huang
authors.affiliation: Department of Neurology, Xuzhou Central Hospital, Xuzhou, 221009, Jiangsu, China.
authors.forename: Zhi-Gang
authors.initials: ZG
authors.lastname: Yu
mesh_terms: D000368:Aged; D020526:Brain Stem Infarctions / Q000097:blood* / Q000175:diagnosis; D002097:C-Reactive Protein / Q000378:metabolism*; D005260:Female; D005947:Glucose / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D012720:Severity of Illness Index; D020521:Stroke / Q000097:blood / Q000175:diagnosis
chemical_list: D002097:C-Reactive Protein; D005947:Glucose
keywords: Acute brainstem infarction; Prognosis; Severity; hs-CRP