title: Advanced drug delivery nanosystems: perspectives and regulatory issues.
abstract: This chapter deals with the classification of Drug Delivery nano Systems (DDnSs) with a Modulatory Controlled Release profile (MCR) denoted as Modulatory Controlled Release nano Systems (MCRnSs). Conventional (c) and advanced (a) DDnSs are denoted by the acronyms cDDnSs and aDDnSs, and can be composed of a single or more than one biomaterials, respectively. The classification was based on their characteristics such as surface functionality (f), the nature of biomaterials used, and the kind of interactions between biomaterials. The aDDnSs can be classified as Hybridic (Hy-) or Chimeric (Chi-) based on the nature-same or different, respectively-of biomaterials and inorganic materials used. The nature of the elements used for producing advanced biomaterials is of great importance and medicinal chemistry contributes effectively to the production of aDDnSs.
authors.affiliation: Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Athens, Panepistimioupolis Zografou, Athens, 15771, Greece, demetzos@pharm.uoa.gr.
authors.forename: Costas
authors.initials: C
authors.lastname: Demetzos
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry; D003692:Delayed-Action Preparations / Q000008:administration & dosage* / Q000737:chemistry; D016503:Drug Delivery Systems / Q000145:classification / Q000379:methods*; D008081:Liposomes / Q000737:chemistry; D049329:Nanostructures / Q000008:administration & dosage* / Q000737:chemistry; D036103:Nanotechnology / Q000379:methods*; D004364:Pharmaceutical Preparations / Q000008:administration & dosage* / Q000737:chemistry; D015203:Reproducibility of Results
chemical_list: D001672:Biocompatible Materials; D003692:Delayed-Action Preparations; D008081:Liposomes; D004364:Pharmaceutical Preparations