title: Validation of phototesting for estimation of individual skin ultraviolet sensitivity based on a lengthwise attenuating ultraviolet B field.
abstract: Conventional skin UV-sensitivity phototesting is based on semi-quantitative assessment of minimal erythema dose (MED). This study demonstrates a method for quantitative MED determination, using a lengthwise attenuating UVB-field combined with tissue viability imaging (TiVi). The study aim was to investigate the agreement between MED acquired by traditional phototest and by the new method. Forty-seven voluntary subjects underwent phototesting with a traditional phototest and with the new technique. Test reading, carried out after 24 h, showed moderate agreement between the methods when assessed with TiVi (Kappa value=0.46) and visually (Kappa value=0.48). For the new method, no systematic differences were seen between outcomes assessed with TiVi or visually (95% CI for the mean difference=-1.6-2.0). In conclusion, the results give promising support for the concept of achieving a more precise MED estimation by combining continuous attenuating UV fields with new available bioengineering technology.
authors.affiliation: Department of Medical and Health Sciences, Division of Community Medicine, Primary Care, Linköping University , Sweden .
authors.forename: E
authors.initials: E
authors.lastname: Pettersson
authors.forename: C D
authors.initials: CD
authors.lastname: Anderson
authors.forename: J
authors.initials: J
authors.lastname: Henricsson
authors.forename: M
authors.initials: M
authors.lastname: Falk
mesh_terms: D000328:Adult; D003952:Diagnostic Imaging / Q000295:instrumentation*; D004890:Erythema / Q000175:diagnosis* / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000528:radiation effects*; D012879:Skin Physiological Phenomena; D014466:Ultraviolet Rays / Q000009:adverse effects; D055815:Young Adult
keywords: Erythema; phototesting; tissue viability imaging