title: Simulation of the Velocity and Temperature Distribution of Inhalation Thermal Injury in a Human Upper Airway Model by Application of Computational Fluid Dynamics.
abstract: Inhalation injury is an important cause of death after thermal burns. This study was designed to simulate the velocity and temperature distribution of inhalation thermal injury in the upper airway in humans using computational fluid dynamics. Cervical computed tomography images of three Chinese adults were imported to Mimics software to produce three-dimensional models. After grids were established and boundary conditions were defined, the simulation time was set at 1 minute and the gas temperature was set to 80 to 320°C using ANSYS software (ANSYS, Canonsburg, PA) to simulate the velocity and temperature distribution of inhalation thermal injury. Cross-sections were cut at 2-mm intervals, and maximum airway temperature and velocity were recorded for each cross-section. The maximum velocity peaked in the lower part of the nasal cavity and then decreased with air flow. The velocities in the epiglottis and glottis were higher than those in the surrounding areas. Further, the maximum airway temperature decreased from the nasal cavity to the trachea. Computational fluid dynamics technology can be used to simulate the velocity and temperature distribution of inhaled heated air.
authors.affiliation: From the *Department of Burns, Beijing Jishuitan Hospital, PR China; and †Peking University Health Science Center, Beijing, PR China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Chang
authors.forename: Xiao-zhuo
authors.initials: XZ
authors.lastname: Zhao
authors.forename: Cheng
authors.initials: C
authors.lastname: Wang
authors.forename: Fang-gang
authors.initials: FG
authors.lastname: Ning
authors.forename: Guo-an
authors.initials: GA
authors.lastname: Zhang
mesh_terms: D000328:Adult; D002059:Burns, Inhalation / Q000503:physiopathology*; D003198:Computer Simulation; D005260:Female; D006801:Humans; D057446:Hydrodynamics; D008297:Male; D012137:Respiratory System / Q000503:physiopathology*; D012984:Software; D013696:Temperature