title: Glial tumors with neuronal differentiation.
abstract: Immunohistochemical studies for neuronal differentiation in glial tumors revealed subsets of tumors having both characteristics of glial and neuronal lineages. Glial tumors with neuronal differentiation can be observed with diverse phenotypes and histologic grades. The rosette-forming glioneuronal tumor of the fourth ventricle and papillary glioneuronal tumor have been newly classified as distinct disease entities. There are other candidates for classification, such as the glioneuronal tumor without pseudopapillary architecture, glioneuronal tumor with neuropil-like islands, and the malignant glioneuronal tumor. The clinical significance of these previously unclassified tumors should be confirmed.
authors.affiliation: Department of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 110-744, Korea. Electronic address: nsckpark@snu.ac.kr.
authors.forename: Chul-Kee
authors.initials: CK
authors.lastname: Park
authors.affiliation: Division of Pediatric Neurosurgery, Department of Neurosurgery, Seoul National University Children's Hospital, 101 Daehak-ro, Jongno-gu, Seoul 110-744, Korea.
authors.forename: Ji Hoon
authors.initials: JH
authors.lastname: Phi
authors.affiliation: Department of Pathology, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 110-744, Korea.
authors.forename: Sung-Hye
authors.initials: SH
authors.lastname: Park
mesh_terms: D002454:Cell Differentiation; D016543:Central Nervous System Neoplasms / Q000473:pathology*; D005910:Glioma / Q000473:pathology*; D006801:Humans; D009474:Neurons / Q000473:pathology*
keywords: Glioneuronal tumor with neuropil-like islands; Glioneuronal tumors without pseudopapillary architecture; Malignant glioneuronal tumor; Neuronal differentiation; Papillary glioneuronal tumor; Rosette-forming glioneuronal tumor of the fourth ventricle