title: Epigenetic alterations of the Wnt signaling pathway in cancer: a mini review.
abstract: Epigenetic mechanisms play a crucial role in cellular proliferation, migration and differentiation in both normal and neoplastic development. One of the key signaling pathways whose components are altered through the epigenetic mechanisms is the Wnt signaling pathway. In this review, we briefly discuss the key concepts of epigenetics and focus on the recent advances in the Wnt signaling pathway research and its potential diagnostic and therapeutic implications.
authors.affiliation: Department of Biology, School of Medicine, University of Zagreb. sermanl@mef.hr.
authors.forename: Ljiljana
authors.initials: L
authors.lastname: Serman
authors.forename: Tamara
authors.initials: T
authors.lastname: Nikuseva Martic
authors.forename: Alan
authors.initials: A
authors.lastname: Serman
authors.forename: Semir
authors.initials: S
authors.lastname: Vranic
mesh_terms: D002454:Cell Differentiation / Q000235:genetics; D002465:Cell Movement / Q000235:genetics; D049109:Cell Proliferation / Q000235:genetics; D019175:DNA Methylation / Q000235:genetics; D044127:Epigenesis, Genetic; D005260:Female; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000235:genetics* / Q000378:metabolism* / Q000473:pathology; D060449:Wnt Signaling Pathway / Q000235:genetics*