title: [Peculiarities of antioxidants as radioprotectors under radiation damage of different extent].
abstract: Results of the own and literature data about the effectiveness of antioxidants as radioprotectors under the action of ionizing irradiation in animals are generalized dependingon the extent of the radiation damage and the linear energy loss of radiation. The initial antioxidant status of tissues is shown to make a different con- tribution in the manifestation of the radioprotective properties of natural and synthetic antioxidants owing to the non-linearity of the lipid peroxidation processes depending on the radiation dose and dose rate. Thus, a complex approach and consideration of the time factor are necessary when estimating radioprotective effectiveness of antioxidants as radoprotectors under radiation damage of different extent.
authors.forename: L N
authors.initials: LN
authors.lastname: Shishkina
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage*; D015227:Lipid Peroxidation / Q000187:drug effects / Q000528:radiation effects; D011829:Radiation Dosage; D011832:Radiation Injuries / Q000188:drug therapy* / Q000473:pathology; D011837:Radiation-Protective Agents / Q000008:administration & dosage*
chemical_list: D000975:Antioxidants; D011837:Radiation-Protective Agents