title: 3-Pyrrolyl-oxindoles as efficient nucleophiles for organocatalytic asymmetric synthesis of structurally diverse 3,3'-disubstituted oxindole derivatives.
abstract: A range of 3-pyrrolyl-3,3'-disubstituted oxindoles were smoothly obtained via the reaction of 3-pyrrolyl-oxindoles with nitroalkenes using an organocatalyst. The usefulness of the protocol was also demonstrated by the versatile conversions of the Michael adducts into other functionalized 3,3'-disubstituted oxindoles, as well as into the analogues of some valuable natural products.
authors.affiliation: National Engineering Research Center of Chiral Drugs, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China. yuanwc@cioc.ac.cn.
authors.forename: Bao-Dong
authors.initials: BD
authors.lastname: Cui
authors.forename: Yong
authors.initials: Y
authors.lastname: You
authors.forename: Jian-Qiang
authors.initials: JQ
authors.lastname: Zhao
authors.forename: Jian
authors.initials: J
authors.lastname: Zuo
authors.forename: Zhi-Jun
authors.initials: ZJ
authors.lastname: Wu
authors.forename: Xiao-Ying
authors.initials: XY
authors.lastname: Xu
authors.forename: Xiao-Mei
authors.initials: XM
authors.lastname: Zhang
authors.forename: Wei-Cheng
authors.initials: WC
authors.lastname: Yuan
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D009574:Nitro Compounds / Q000737:chemistry*; D000078183:Oxindoles; D011758:Pyrroles / Q000737:chemistry*
chemical_list: D000475:Alkenes; D007211:Indoles; D009574:Nitro Compounds; D000078183:Oxindoles; D011758:Pyrroles; C022960:2-oxindole