title: Pipette-tip solid-phase extraction by use of a sol-gel hybrid adsorbent: a new pretreatment strategy for rapid screening of cucumbers for cyanazine and atrazine.
abstract: A pipette-tip solid-phase extraction (PT-SPE) method using a sol-gel hybrid adsorbent has been developed. The method could be used for rapid screening of vegetable matrices for cyanazine and atrazine; assay of cucumbers is reported as an example. The sol-gel hybrid adsorbent was synthesized from tetraethyl orthosilicate (TEOS) as the precursor and γ-(methacryloyloxy)propyltrimethoxysilane (KH570) as both surface modifying agent and monomer for the polymerization. Under the optimized conditions, good calibration linearity was obtained in the range 0.022-1.65 μg g(-1) with correlation coefficients (r) ≥0.9996. Recovery at three spike levels ranged from 87.6 to 93.8 % with relative standard deviations ≤7.8 %. This extraction strategy has several advantages, for example ease of assembly, low cost, and high extraction efficiency, and is a potential pretreatment strategy for rapid screening of cyanazine and atrazine in vegetables.
authors.affiliation: Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education and Key Laboratory of Pharmaceutical Quality Control of Hebei Province and College of Pharmacy, Hebei University, Baoding, 071002, China.
authors.forename: Mingyu
authors.initials: M
authors.lastname: Wang
authors.forename: Hongyuan
authors.initials: H
authors.lastname: Yan
authors.forename: Yanan
authors.initials: Y
authors.lastname: Yuan
authors.forename: Yehong
authors.initials: Y
authors.lastname: Han
mesh_terms: D000327:Adsorption; D001280:Atrazine / Q000032:analysis*; D018553:Cucumis sativus / Q000737:chemistry*; D005504:Food Analysis / Q000379:methods*; D008689:Methacrylates / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D012821:Silanes / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000379:methods*; D013499:Surface Properties; D013997:Time Factors; D014227:Triazines / Q000032:analysis*
chemical_list: D008689:Methacrylates; D012821:Silanes; D014227:Triazines; C017492:methacryloxypropyltrimethoxysilane; C040733:tetraethoxysilane; D001280:Atrazine; C007168:cyanazine