title: Propofol alternatives in gastrointestinal endoscopy anesthesia.
abstract: Although propofol has been the backbone for sedation in gastrointestinal endoscopy, both anesthesiologists and endoscopists are faced with situations where an alternative is needed. Recent national shortages forced many physicians to explore these options. A midazolam and fentanyl combination is the mainstay in this area. However, there are other options. The aim of this review is to explore these options. The future would be, invariably, to move away from propofol. The reason is not in any way related to the drawbacks of propofol as a sedative. The mandate that requires an anesthesia provider to administer propofol has been a setback in many countries. New sedative drugs like Remimazolam might fill this void in the future. In the meantime, it is important to keep an open eye to the existing alternatives.
authors.affiliation: Department of Clinical Anesthesiology and Critical Care, Perelman School of Medicine, 680 Dulles Building, 3400 Spruce Street, Philadelphia, PA 19104, USA.
authors.forename: Basavana Gouda
authors.initials: BG
authors.lastname: Goudra
authors.affiliation: Department of Anesthesia, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Preet Mohinder
authors.initials: PM
authors.lastname: Singh
keywords: GI endoscopy sedation; non-anesthetist administered propofol; propofol Remimazolam; propofol complications in sedation