title: Application of molecular imprinted polymer nanoparticles as a selective solid phase extraction for preconcentration and trace determination of 2,4-dichlorophenoxyacetic acid in the human urine and different water samples.
abstract: A molecular-imprinted polymer nanoparticles (MIP-NP) for the selective preconcentration of 2,4-dichlorophenoxyacetic acid (2,4-D) is described. It was obtained by precipitation polymerization from methacrylic acid (the functional monomer), ethylene glycol dimethacrylate (the cross-linker), 2,2'-azobisisobutyronitrile (the initiator) and 2,4-D (the template molecule) in acetonitrile solution. The MIP-NPs were characterized by thermogravimetric analysis, and by scanning electron microscopy. Imprinted 2,4-D molecules were removed from the polymeric structure using acetic acid in methanol (15:85 v/v %) as the eluting solvent. The sorption and desorption process occur within 10 min and 15 min, respectively. The maximum sorbent capacity of the molecular imprinted polymer is 89.2 mg g(-1). The relative standard deviation and limit of detection for water samples by introduced selective solid phase extraction were 4.2% and 1.25 μg L(-1), and these data for urine samples were 4.7% and 1.80 μg L(-1), respectively. The method was applied to the determination of 2,4-D in the urine and different water samples.
authors.affiliation: Department of Occupational Health Engineering, School of Public Health, Shahroud University of Medical Sciences, Shahroud, Iran.
authors.forename: Fariborz
authors.initials: F
authors.lastname: Omidi
authors.affiliation: Department of Chemistry, Shahid Beheshti University, Tehran, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Behbahani
authors.affiliation: Department of Chemistry, Shahid Beheshti University, Tehran, Iran.
authors.forename: Hamid
authors.initials: H
authors.lastname: Sadeghi Abandansari
authors.affiliation: Department of Occupational Health, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Alireza
authors.initials: A
authors.lastname: Sedighi
authors.affiliation: Department of Occupational Health Engineering, School of Public Health and Institute for Environmental Research, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Seyed Jamaleddin
authors.initials: SJ
authors.lastname: Shahtaheri
keywords: 2,4-dichlorophenoxyacetic acid; Molecular imprinted polymer nanoparticles; Selective preconcentration; Urine and water samples