title: Optical coherence elastography for tissue characterization: a review.
abstract: Optical coherence elastography (OCE) represents the frontier of optical elasticity imaging techniques and focuses on the micro-scale assessment of tissue biomechanics in 3D that is hard to achieve with traditional elastographic methods. Benefit from the advancement of optical coherence tomography, and driven by the increasing requirements in nondestructive biomechanical characterization, this emerging technique recently has experienced a rapid development. In this paper, we start with the description of the mechanical contrast that has been employed by OCE and review the state-of-the-art techniques based on the reported applications and discuss the current technical challenges, emphasizing the unique role of OCE in tissue mechanical characterization. The position of OCE among other elastography techniques.
authors.affiliation: Department of Biomedical Engineering, University of Houston, 3605 Cullen Blvd., Houston, Texas, 77204-5060, USA; Department of Molecular Physiology and Biophysics, Baylor College of medicine, one Baylor Plaza, Houston, Texas, 77030, USA.
authors.forename: Shang
authors.initials: S
authors.lastname: Wang
authors.forename: Kirill V
authors.initials: KV
authors.lastname: Larin
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D054459:Elasticity Imaging Techniques / Q000379:methods*; D006801:Humans; D041623:Tomography, Optical Coherence / Q000379:methods*
keywords: Young's modulus; biomechanics; elastic wave; natural frequency; optical coherence elastography; optical coherence tomography; strain; tissue characterization