title: Whither pertussis?
abstract: Several lines of evidence suggest that pertussis disease will continue to rise in countries which have switched to acellular vaccines. While maternal vaccination is promising as a mitigating strategy it is unlikely to replace the need for a better vaccine. In the absence of a clear alternative, a return to using whole cell vaccines, at least in part, should not be dismissed as an option without contemporary studies of feasibility and acceptability.
authors.affiliation: Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, 100 Roberts Road, Subiaco, Perth, WA 6008.
authors.forename: Thomas L
authors.initials: TL
authors.lastname: Snelling
authors.forename: Claire S
authors.initials: CS
authors.lastname: Waddington
mesh_terms: D001886:Bordetella pertussis / Q000276:immunology*; D006801:Humans; D010567:Pertussis Vaccine / Q000276:immunology*; D014611:Vaccination; D022282:Vaccines, Acellular / Q000276:immunology*; D014917:Whooping Cough / Q000453:epidemiology / Q000517:prevention & control*
chemical_list: D010567:Pertussis Vaccine; D022282:Vaccines, Acellular
keywords: acellular vaccine; disease prevention; epidemic; pertussis; vaccine; whole cell vaccine