title: Resistant depressions.
abstract: The concept of Resistant Depression was introduced for the first time in 1974 by Leiman. Despite the numerous studies in this regard, it was not possible to give a precise definition of this problem and to identify a safe etiology. This work aims to contribute through a literature review and exposure of two clinical cases, to better define and analyze this phenomenon by assuming the possible therapeutic strategies for patients with resistant depression.
authors.affiliation: Mental Health Center, Catanzaro Lido, via Milano 28, 88024 Girifalco, Italy, straniti@virgilio.it.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Stranieri