title: Modern drug development: which patients should come first?
authors.affiliation: Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
authors.forename: Muthiah
authors.initials: M
authors.lastname: Vaduganathan
authors.affiliation: Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.
authors.forename: Vinay
authors.initials: V
authors.lastname: Prasad
mesh_terms: D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy; D055808:Drug Discovery; D064420:Drug-Related Side Effects and Adverse Reactions; D006333:Heart Failure / Q000188:drug therapy; D006801:Humans; D016032:Randomized Controlled Trials as Topic
chemical_list: D061067:Antibodies, Monoclonal, Humanized; C485206:pertuzumab