title: Spirometric evaluation in juvenile systemic lupus erythematosus.
abstract: OBJECTIVE
  Spirometric evaluation in juvenile systemic lupus erythematosus.
  
  
  METHODS
  Forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1/FVC, forced expiratory flow between 25-75% of vital capacity (FEF25-75%) and peak expiratory flow rate (PEFR) of 21 patients with juvenile SLE (jSLE) were compared to controls.
  
  
  RESULTS
  Reduced FVC and FEF25-75% was found in 18 and 9 patients, respectively. All had normal FEV1/FVC. None had respiratory complaint. When compared to controls, patients had significantly reduced FVC [mean (SD):1.97 (0.56) vs 2.35 (0.60), P=0.002] and FEF25-75% [2.19 (0.83) vs 2.63 (0.76), P=0.028] but similar FEV1/FVC [86.87(7.03) vs 86.72 (6.35), P=0.639].
  
  
  CONCLUSIONS
  jSLE patients had significant restrictive pattern and small airway involvement.
authors.affiliation: Departments of Physiology and *Pediatric Rheumatology, Institute of Postgraduate Medical Education and Research, Kolkata, India. Correspondence to: Dr Md Mahboob Alam, Assistant Professor, Department of Physiology, IPGMER, 54, Alimuddin Street, Kolkata 700 016, India. mdmahboobalam@gmail.com.
authors.forename: Md Mahboob
authors.initials: MM
authors.lastname: Alam
authors.forename: Sumantra
authors.initials: S
authors.lastname: Sarkar
authors.forename: Parasar
authors.initials: P
authors.lastname: Ghosh
authors.forename: Biman
authors.initials: B
authors.lastname: Ray
authors.forename: Rakesh
authors.initials: R
authors.lastname: Mondal
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D005541:Forced Expiratory Volume / Q000502:physiology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis* / Q000453:epidemiology* / Q000503:physiopathology*; D008297:Male; D013147:Spirometry; D014797:Vital Capacity / Q000502:physiology