title: "I Have Remained Strong Because of That Food": Acceptability and Use of Lipid-Based Nutrient Supplements Among Pregnant HIV-Infected Ugandan Women Receiving Combination Antiretroviral Therapy.
abstract: We evaluated the acceptability and use of macronutrient supplementation among HIV-infected pregnant Ugandan women receiving antiretroviral therapy in a clinical study (NCT 00993031). We first conducted formative research among 56 pregnant and lactating women to select a supplement regimen. Acceptability and use of the supplementation regimen (35 sachets of lipid-based nutrient supplements (LNS) and 4 or 6 kg of instant soy porridge for the household provided monthly) were evaluated among 87 pregnant women. Organoleptic assessments of LNS were favorable. Participants reported consuming LNS a mean of 6.1 days per week, and adherence to recommended consumption behaviors (e.g. frequency, quantity, not sharing) was >80 %. Few women reported negative social consequences of supplementation. The majority of participants also consumed most of the porridge intended for the household. In sum, LNS was acceptable and used regularly. Larger studies to evaluate physical and psychosocial consequences of LNS during pregnancy among HIV-infected women are warranted.
authors.affiliation: Division of Nutritional Sciences, Cornell University, 113 Savage Hall, Ithaca, NY, 14850, USA, sera.young@cornell.edu.
authors.forename: Sera
authors.initials: S
authors.lastname: Young
authors.forename: Barnabas
authors.initials: B
authors.lastname: Natamba
authors.forename: Flavia
authors.initials: F
authors.lastname: Luwedde
authors.forename: Dorcas
authors.initials: D
authors.lastname: Nyafwono
authors.forename: Ben
authors.initials: B
authors.lastname: Okia
authors.forename: Beth
authors.initials: B
authors.lastname: Osterbauer
authors.forename: Paul
authors.initials: P
authors.lastname: Natureeba
authors.forename: Lynn
authors.initials: L
authors.lastname: Johnson
authors.forename: Chloe
authors.initials: C
authors.lastname: Michel
authors.forename: Amy
authors.initials: A
authors.lastname: Zheng
authors.forename: Marion
authors.initials: M
authors.lastname: Robine
authors.forename: Jane
authors.initials: J
authors.lastname: Achan
authors.forename: Edwin
authors.initials: E
authors.lastname: Charlebois
authors.forename: Deb
authors.initials: D
authors.lastname: Cohan
authors.forename: Diane
authors.initials: D
authors.lastname: Havlir
mesh_terms: D000328:Adult; D044966:Anti-Retroviral Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active; D001942:Breast Feeding; D003258:Consumer Behavior; D004041:Dietary Fats / Q000008:administration & dosage*; D019587:Dietary Supplements; D005260:Female; D005500:Follow-Up Studies; D005527:Food, Fortified; D015658:HIV Infections / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D007407:Interviews as Topic; D044342:Malnutrition / Q000517:prevention & control; D010342:Patient Acceptance of Health Care / Q000706:statistics & numerical data*; D011247:Pregnancy; D037841:Pregnant People; D036301:Qualitative Research; D014454:Uganda / Q000453:epidemiology
chemical_list: D044966:Anti-Retroviral Agents; D004041:Dietary Fats