title: Individualized factor IX dosing in two brothers: application of longitudinal pharmacokinetic modelling to optimize therapeutic benefit.
authors.affiliation: Division of Clinical Pharmacology and Therapeutic Innovation, Children's Mercy Hospitals and Clinics, Kansas, Missouri, USA.
authors.forename: J T
authors.initials: JT
authors.lastname: Brown
authors.affiliation: Division of Hematology and Oncology, Children's Mercy Hospitals and Clinics, Kansas, Missouri, USA.|Department of Pediatrics, School of Medicine, University of Missouri-Kansas City, Kansas, Missouri, USA.
authors.forename: B M
authors.initials: BM
authors.lastname: Wicklund
authors.affiliation: Division of Clinical Pharmacology and Therapeutic Innovation, Children's Mercy Hospitals and Clinics, Kansas, Missouri, USA.|Department of Pediatrics, School of Medicine, University of Missouri-Kansas City, Kansas, Missouri, USA.
authors.forename: S M
authors.initials: SM
authors.lastname: Abdel-Rahman
mesh_terms: D002675:Child, Preschool; D016903:Drug Monitoring; D005164:Factor IX / Q000008:administration & dosage* / Q000493:pharmacokinetics*; D002836:Hemophilia B / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D008297:Male; D057285:Precision Medicine; D035781:Siblings; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D005164:Factor IX