title: Palladium(II)-catalyzed oxidative dearomatization of free naphthols with two alkyne units.
abstract: Readily available 2-naphthols undergo [2 + 2 + 1] spiroannulation reactions with alkynes in the presence of a Pd(II) catalyst and an oxidant. This process relies on C-H functionalization and naphthyl ring dearomatization at the 1-position of 2-naphthols to provide a variety of spirocyclic compounds. Using alkyl-aryl alkynes as the coupling partners led to regioisomeric mixtures in favor of the head-to-tail isomer bearing a quaternary carbon stereocenter.
authors.forename: Songlin
authors.initials: S
authors.lastname: Gu
authors.forename: Lei
authors.initials: L
authors.lastname: Luo
authors.forename: Jingjing
authors.initials: J
authors.lastname: Liu
authors.forename: Lu
authors.initials: L
authors.lastname: Bai
authors.forename: Huayu
authors.initials: H
authors.lastname: Zheng
authors.forename: Yaoyu
authors.initials: Y
authors.lastname: Wang
authors.forename: Xinjun
authors.initials: X
authors.lastname: Luan