title: Method to measure the 3D angular orientation of the aortic valve plane from a single image of a valvuloplasty balloon: findings of a large animal proof of concept experiment.
abstract: During transcatheter aortic valve replacement procedures, alignment of the interventional x-ray beam with the aortic valve plane is required to guide valve placement. The purpose of this work was to develop methods to measure x-ray beam angles which are aligned with the aortic valve plane from a single x-ray image of a valvuloplasty balloon inflated across the left ventricular outflow tract (LVOT). A custom valvuloplasty balloon and image analytics were developed. In-vivo pig experiments demonstrated that the angular orientation of the LVOT can be measured with precision less than 3°, including the influence of cardiac motion during rapid pacing. Using these methods, the angular orientation of the LVOT of a large mammal can be measured precisely and the continuous range of x-ray projection angles which are aligned with the aortic valve plane can be calculated.
authors.affiliation: Division of Cardiovascular Diseases, Mayo Clinic , 200 1st St SW, Rochester, MN 55905 , USA.
authors.forename: Kenneth A
authors.initials: KA
authors.lastname: Fetterly
authors.forename: Verghese
authors.initials: V
authors.lastname: Mathew
mesh_terms: D000792:Angiography / Q000379:methods*; D000818:Animals; D001021:Aortic Valve / Q000000981:diagnostic imaging* / Q000601:surgery; D063126:Balloon Valvuloplasty / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D025321:Surgery, Computer-Assisted / Q000379:methods*; D013552:Swine
keywords: 3D angular orientation; aortic valve; interventional x-ray imaging; transcatheter aortic valve replacement