title: Genetic polymorphism of ten MiniSTR loci in the population of Punjab Pakistan for forensic application.
abstract: Ten MiniSTR loci were analyzed on 250 unrelated individuals of Punjabi population from Punjab province of Pakistan. The product amplification range is from 65 to 280 bp. Allele frequency for a total of 98 observed alleles is from 0.002 to 0.41. Forensic and paternity statistical parameters were investigated including combined power of discrimination (PD), combined power of exclusion (PE), and cumulative probability of matching (PM) equaled to 0.99999999999824, 0.999824, and 1.75931 × 10(-12), respectively. These MiniSTRs on the basis of high degree polymorphism and fragment size reduction will be highly informative in most of the forensic cases where DNA of the samples is degraded, mass disasters, and dead body identification. Significant differences were observed in all loci when comparing with same STR loci in previously published different world populations.
authors.affiliation: Forensic DNA Typing Laboratory, National Centre of Excellence in Molecular Biology, University of the Punjab Lahore, Lahore, 53700, Pakistan.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Shafique
authors.forename: Muhammad Saqib
authors.initials: MS
authors.lastname: Shahzad
authors.forename: Muhammad Adnan
authors.initials: MA
authors.lastname: Shan
authors.forename: Azam
authors.initials: A
authors.lastname: Ali
authors.forename: Ziaur
authors.initials: Z
authors.lastname: Rahman
authors.forename: Tayyab
authors.initials: T
authors.lastname: Husnain
mesh_terms: D016172:DNA Fingerprinting; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D018895:Microsatellite Repeats; D010154:Pakistan; D011110:Polymorphism, Genetic; D060888:Real-Time Polymerase Chain Reaction