title: Ordered, adherent layers of nanofibers enabled by supramolecular interactions.
abstract: Aligned nanofibrous substrates can be created by electrospinning, but methods for creating multilamellar structures of aligned fibers are limited. Here, apposed nanofibrous scaffolds with pendantβ-cyclodextrin (CD) were adhered together by adamantane (Ad) modified hyaluronic acid, exploiting the guest-host interactions of CD and Ad for macroscopic assembly. Stable user-defined multi-layered scaffolds were formed for cell culture or tissue engineering.
authors.affiliation: Department of Bioengineering, University of Pennsylvania, 240 Skirkanich Hall, 210 South 33 Street, Philadelphia, PA 19104, USA.
authors.forename: Christopher B
authors.initials: CB
authors.lastname: Highley
authors.affiliation: Department of Bioengineering, University of Pennsylvania, 240 Skirkanich Hall, 210 South 33 Street, Philadelphia, PA 19104, USA.
authors.forename: Christopher B
authors.initials: CB
authors.lastname: Rodell
authors.affiliation: Department of Bioengineering, University of Pennsylvania, 240 Skirkanich Hall, 210 South 33 Street, Philadelphia, PA 19104, USA.
authors.forename: Iris L
authors.initials: IL
authors.lastname: Kim
authors.affiliation: Department of Bioengineering, University of Pennsylvania, 240 Skirkanich Hall, 210 South 33 Street, Philadelphia, PA 19104, USA.
authors.forename: Ryan J
authors.initials: RJ
authors.lastname: Wade
authors.affiliation: Department of Bioengineering, University of Pennsylvania, 240 Skirkanich Hall, 210 South 33 Street, Philadelphia, PA 19104, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Burdick