title: Association of salivary triglycerides and cholesterol with dental caries in children with type 1 diabetes mellitus.
abstract: BACKGROUND
  Metabolic disturbances in diabetes mellitus can affect oral health. Altered levels of salivary lipids have been suggested as a risk for dental caries. There has been lack of research in this regard and in children with type 1 diabetes mellitus.
  
  
  OBJECTIVE
  To assess the salivary triglycerides and cholesterol levels in children with type 1 diabetes mellitus and correlate them with their dental caries status.
  
  
  METHODS
  Thirty children aged 12-16 years with type 1 diabetes mellitus and 30 age- and gender-matched healthy children were included in the study. Unstimulated saliva was collected from each child and evaluated for salivary triglyceride and cholesterol levels. Dental caries status (DMFT) was recorded.
  
  
  RESULTS
  Salivary cholesterol and triglyceride levels were significantly higher in children with type 1 diabetes mellitus (p ≤ 0.05). In comparison to controls, mean DMFT score was higher in the diabetic children. Salivary triglycerides showed a significant correlation with dental caries status in the study group (p = 0.035). In normal children, salivary cholesterol levels showed a significant association with dental caries. (p = 0.008).
  
  
  CONCLUSIONS
  Both salivary cholesterol and triglycerides levels were significantly higher in children with type 1 diabetes mellitus. Salivary triglycerides showed a significant association with dental caries in these children.
authors.affiliation: Principal, Professor and Head, Department of Pedodontics and Preventive Dentistry, The Oxford Dental College and Hospital, Bangalore, India.
authors.forename: Priya
authors.initials: P
authors.lastname: Subramaniam
authors.forename: Akhliesh
authors.initials: A
authors.lastname: Sharma
authors.forename: Keerthan
authors.initials: K
authors.lastname: Kaje
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D002784:Cholesterol / Q000378:metabolism*; D004245:DMF Index; D003731:Dental Caries / Q000378:metabolism*; D003922:Diabetes Mellitus, Type 1 / Q000378:metabolism*; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D012307:Risk Factors; D012463:Saliva / Q000737:chemistry*; D014280:Triglycerides / Q000378:metabolism*
chemical_list: D014280:Triglycerides; D002784:Cholesterol
keywords: dental caries; salivary cholesterol; salivary triglycerides; type 1 diabetes mellitus