title: A review of neuroimaging biomarkers of Alzheimer's disease.
abstract: Neuroimaging biomarkers have potential role in the early diagnosis as well as periodic follow-up of neurodegenerative diseases such as Alzheimer's disease (AD). Structural imaging biomarkers can be used to predict those who are at risk or in preclinical stages of AD. It could possibly be useful even in predicting the conversion of Mild Cognitive Impairment (MCI) an early stage of AD to AD. In addition there has been a lot of progress in molecular imaging in AD. This article presents a review of recent progress in selected imaging biomarkers for early diagnosis, classification, and progression, of AD. A comprehensive integrative strategy initiated early in the cognitive decline is perhaps the most effective method of controlling progression to Alzheimer's disease.
authors.affiliation: Cognition and Behavioral Neurology Section, Department of Neurology, Trivandrum ; Department of Electronics and Instrumentation, Noorul Islam University, Kumaracoil, Thuckalay, Tamilnadu.
authors.forename: Tinu
authors.initials: T
authors.lastname: Varghese
authors.affiliation: Cognition and Behavioral Neurology Section, Department of Neurology, Trivandrum.
authors.forename: R
authors.initials: R
authors.lastname: Sheelakumari
authors.affiliation: Department of Imaging Sciences and Interventional Radiology, Sree Chitra Tirunal Institute for Medical Science and Technology, Trivandrum.
authors.forename: Jija S
authors.initials: JS
authors.lastname: James
authors.affiliation: Cognition and Behavioral Neurology Section, Department of Neurology, Trivandrum ; Cognition & Behavioural Neurology Section, Department of Neurology, National Institute of Mental Health & Neuro Sciences, Banglore, India.
authors.forename: Ps
authors.initials: P
authors.lastname: Mathuranath