title: GenePainter v. 2.0 resolves the taxonomic distribution of intron positions.
abstract: Conserved intron positions in eukaryotic genes can be used to reconstruct phylogenetic trees, to resolve ambiguous subfamily relationships in protein families and to infer the history of gene families. This version of GenePainter facilitates working with large datasets through options to select specific subsets for analysis and visualization, and through providing exhaustive statistics. GenePainter's application in phylogenetic analyses is considerably extended by the newly implemented integration of the exon-intron pattern conservation with phylogenetic trees.
  
  
  METHODS
  The software along with detailed documentation is available at http://www.motorprotein.de/genepainter and as Supplementary Material.
  
  
  BACKGROUND
  mako@nmr.mpibpc.mpg.de
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors.affiliation: Group Systems Biology of Motor Proteins, Department of NMR-based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany.
authors.forename: Stefanie
authors.initials: S
authors.lastname: Mühlhausen
authors.affiliation: Group Systems Biology of Motor Proteins, Department of NMR-based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany.
authors.forename: Marcel
authors.initials: M
authors.lastname: Hellkamp
authors.affiliation: Group Systems Biology of Motor Proteins, Department of NMR-based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Kollmar
mesh_terms: D002874:Chromosome Mapping; D003196:Computer Graphics; D005091:Exons / Q000235:genetics*; D006801:Humans; D007438:Introns / Q000235:genetics*; D008840:Microfilament Proteins / Q000235:genetics*; D010802:Phylogeny; D012984:Software
chemical_list: D008840:Microfilament Proteins; C072061:coronin proteins