title: Esophagitis due to dexketoprofen trometamol: a rare case report.
abstract: Various drugs are known to cause pill esophagitis. Antimicrobial drugs and nonsteroidal anti-inflammatory drugs are the most common causes of pill-induced esophagitis. Most patients suffer only self-limiting pain, but serious complications can occur. A 21-year-old man was admitted to our outpatient clinic with retrosternal chest pain, dysphagia, and odynophagia complaints, which occurred within 2 weeks after starting dexketoprofen trometamol. An upper endoscopy system examination revealed three well-demarcated ulcers in the esophagus at 35 cm from the incisors. Dexketoprofen trometamol may cause esophageal lesions. This rare disorder should be considered in patients presenting with sudden-onset retrosternal pain in addition to dysphagia and odynophagia.
authors.affiliation: Department of Gastroenterology, Medical Faculty, Yuzuncu Yil University, Van, Turkey.
authors.forename: Sehmus
authors.initials: S
authors.lastname: Olmez
authors.forename: Salim
authors.initials: S
authors.lastname: Donmez
authors.forename: Mehmet
authors.initials: M
authors.lastname: Aslan
authors.forename: Sevdegul
authors.initials: S
authors.lastname: Karadas
authors.forename: Alpaslan
authors.initials: A
authors.lastname: Yavuz
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000627:therapeutic use; D002637:Chest Pain / Q000139:chemically induced; D003680:Deglutition Disorders / Q000139:chemically induced; D003937:Diagnosis, Differential; D004941:Esophagitis / Q000139:chemically induced* / Q000175:diagnosis; D004945:Esophagoscopy; D006356:Heartburn / Q000139:chemically induced; D006801:Humans; D007660:Ketoprofen / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male; D012307:Risk Factors; D014325:Tromethamine / Q000009:adverse effects* / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D014325:Tromethamine; D007660:Ketoprofen; C118296:dexketoprofen trometamol