title: Cognitive function in hypertensive children.
abstract: Young hypertensive adults demonstrate decreased performance on neurocognitive testing compared with that of normotensive controls. There is emerging, preliminary evidence that children with hypertension also manifest cognitive differences when compared to normotensive controls. These preliminary studies consist mostly of database and single-center studies that focus primarily on differences in neurocognitive test performance and differences in cerebrovascular reactivity between hypertensive and normotensive subjects. Lessons from the literature on cognition in adult hypertensives and experience from the preliminary studies in children informed the design of a current, multicenter, ongoing study of cognition in children with primary hypertension.
authors.affiliation: Division of Pediatric Nephrology, Department of Pediatrics, University of Rochester Medical Center, 601 Elmwood Ave., Box 777, Rochester, NY, 14642, USA, marc_lande@urmc.rochester.edu.
authors.forename: Marc B
authors.initials: MB
authors.lastname: Lande
authors.forename: Juan C
authors.initials: JC
authors.lastname: Kupferman
mesh_terms: D001794:Blood Pressure / Q000502:physiology*; D002648:Child; D003071:Cognition / Q000502:physiology*; D000075222:Essential Hypertension; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D009483:Neuropsychological Tests