title: The ribosome emerges from a black box.
abstract: Although the basic facts about the ribosome were already known 40 years ago, elucidating its atomic structure and molecular mechanisms required sheer persistence and the innovative use of new technology and methods. These advances have transformed our understanding of translation in the cell.
authors.affiliation: MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK. Electronic address: ramak@mrc-lmb.cam.ac.uk.
authors.forename: V
authors.initials: V
authors.lastname: Ramakrishnan
mesh_terms: D001419:Bacteria / Q000737:chemistry / Q000378:metabolism; D003585:Cell Biology / Q000266:history; D020285:Cryoelectron Microscopy; D018360:Crystallography, X-Ray; D049673:History, 20th Century; D049674:History, 21st Century; D008958:Models, Molecular; D010506:Periodicals as Topic; D014176:Protein Biosynthesis; D016337:RNA, Catalytic / Q000737:chemistry / Q000378:metabolism; D012270:Ribosomes / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D016337:RNA, Catalytic