title: Remodeling Cildb, a popular database for cilia and links for ciliopathies.
abstract: BACKGROUND
  New generation technologies in cell and molecular biology generate large amounts of data hard to exploit for individual proteins. This is particularly true for ciliary and centrosomal research. Cildb is a multi-species knowledgebase gathering high throughput studies, which allows advanced searches to identify proteins involved in centrosome, basal body or cilia biogenesis, composition and function. Combined to localization of genetic diseases on human chromosomes given by OMIM links, candidate ciliopathy proteins can be compiled through Cildb searches.
  
  
  METHODS
  Othology between recent versions of the whole proteomes was computed using Inparanoid and ciliary high throughput studies were remapped on these recent versions.
  
  
  RESULTS
  Due to constant evolution of the ciliary and centrosomal field, Cildb has been recently upgraded twice, with new species whole proteomes and new ciliary studies, and the latter version displays a novel BioMart interface, much more intuitive than the previous ones.
  
  
  CONCLUSIONS
  This already popular database is designed now for easier use and is up to date in regard to high throughput ciliary studies.
authors.affiliation: Centre de Génétique Moléculaire, CNRS, Avenue de la Terrasse, Gif sur Yvette, 91198, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Arnaiz
authors.affiliation: Centre de Génétique Moléculaire, CNRS, Avenue de la Terrasse, Gif sur Yvette, 91198, France.
authors.forename: Jean
authors.initials: J
authors.lastname: Cohen
authors.affiliation: Centre de Génétique Moléculaire, CNRS, Avenue de la Terrasse, Gif sur Yvette, 91198, France.
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Tassin
authors.affiliation: Centre de Génétique Moléculaire, CNRS, Avenue de la Terrasse, Gif sur Yvette, 91198, France.
authors.forename: France
authors.initials: F
authors.lastname: Koll