title: Ultrasensitive SERS assay of lysozyme using a novel and unique four-way helical junction molecule probe for signal amplification.
abstract: A unique four-way helical junction molecule (FHJM) probe was ingeniously designed, and firstly introduced into DNA signal amplification as a novel Surface-enhanced Raman scattering (SERS) probe. Significantly, a new FHJM-SERS method was successfully developed for lysozyme detection with high sensitivity and specificity.
authors.affiliation: Shandong Province Key Laboratory of Detection Technology for Tumor Makers, College of Chemistry and Chemical Engineering, Linyi University, Linyi 276005, P. R. China. shushzhang@126.com.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zhang
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Wang
authors.forename: Fuwei
authors.initials: F
authors.lastname: Zheng
authors.forename: Rui
authors.initials: R
authors.lastname: Ren
authors.forename: Shusheng
authors.initials: S
authors.lastname: Zhang
mesh_terms: D052157:Aptamers, Nucleotide / Q000737:chemistry*; D015374:Biosensing Techniques / Q000379:methods*; D004247:DNA / Q000737:chemistry; D057230:Limit of Detection; D015335:Molecular Probes / Q000737:chemistry*; D009113:Muramidase / Q000032:analysis*; D009690:Nucleic Acid Conformation; D013059:Spectrum Analysis, Raman; D013499:Surface Properties
chemical_list: D052157:Aptamers, Nucleotide; D015335:Molecular Probes; D004247:DNA; D009113:Muramidase