title: Cd(II)-terpyridine-based complex as a ratiometric fluorescent probe for pyrophosphate detection in solution and as an imaging agent in living cells.
abstract: The terpyridine anthracene ligand was synthesized and characterized. is a ratiometric fluorescent probe for Cd(2+) with a recognition mechanism based on intramolecular charge transfer (ICT). An complex was isolated, and its structure was established using single-crystal XRD. The complex was able to serve as a novel reversible chemosensing ensemble to allow ratiometric response to pyrophosphate (PPi) in aqueous media. Moreover, the fluorescence imaging in living cells from these two emission channels suggested that was a ratiometric probe for Cd(2+), and the in situ generated complex was also a ratiometric ensemble for PPi detection in living cells.
authors.affiliation: Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, China. kli@scu.edu.cn xqyu@scu.edu.cn.
authors.forename: Shu-Yan
authors.initials: SY
authors.lastname: Jiao
authors.forename: Kun
authors.initials: K
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Yan-Hong
authors.initials: YH
authors.lastname: Liu
authors.forename: Zeng
authors.initials: Z
authors.lastname: Huang
authors.forename: Xiao-Qi
authors.initials: XQ
authors.lastname: Yu
mesh_terms: D000818:Animals; D002104:Cadmium / Q000737:chemistry*; D002460:Cell Line; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism; D018360:Crystallography, X-Ray; D011756:Diphosphates / Q000032:analysis*; D005456:Fluorescent Dyes / Q000737:chemistry*; D051379:Mice; D018613:Microscopy, Confocal; D008968:Molecular Conformation; D011725:Pyridines / Q000737:chemistry; D012996:Solutions / Q000737:chemistry; D013050:Spectrometry, Fluorescence
chemical_list: D056831:Coordination Complexes; D011756:Diphosphates; D005456:Fluorescent Dyes; D011725:Pyridines; D012996:Solutions; D002104:Cadmium; C107241:diphosphoric acid; C023666:pyridine