title: Can mano-videoendoscopy substitute for videofluorography in evaluation of upper esophageal sphincter function?
abstract: CONCLUSIONS
  Mano-videoendoscopy (MVE), a manometry technique with endoscopic confirmation of the pressure catheter, can supplement the information on upper esophageal sphincter (UES) function, and overcomes the drawbacks of videoendoscopic swallowing study (VESS).
  
  
  OBJECTIVE
  This study aimed to investigate the possibility of replacing videofluorographic swallowing study (VFSS) with MVE, as a test to precisely evaluate UES function.
  
  
  METHODS
  Data from 52 patients with dysphagia were retrospectively reviewed. All patients underwent both MVE and VFSS for evaluation of dysphagia. The manometry was performed with a transnasally inserted catheter (2.6 mm outer diameter and four pressure sensors) under endoscopic observation. The sensors were kept at the tongue base, upper pyriform sinus, apex of pyriform sinus, and UES. We statistically compared the manometric parameters of UES relaxation with fluorographic UES opening.
  
  
  RESULTS
  Fluorographic UES opening was diagnosed as good in 34 patients and poor in 18 patients. The nadir pressure, pressure drop, and pressure rise in the UES had significant correlation on the fluorographic UES opening. Stepwise logistic regression test revealed that pressure drop, the gap between the resting pressure and the nadir of UES pressure, was a robust parameter for predicting fluorographic UES opening, and the cut-off level to anticipate good fluorographic opening was ≥ 33.5 mmHg (specificity, 0.853; sensitivity, 0.759).
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Kyorin University, School of Medicine , Mitaka , Tokyo.
authors.forename: Takehiro
authors.initials: T
authors.lastname: Karaho
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Satoh
authors.forename: Junko
authors.initials: J
authors.lastname: Nakajima
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nakayama
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Kohno
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015154:Esophageal Motility Disorders / Q000175:diagnosis*; D049631:Esophageal Sphincter, Upper / Q000503:physiopathology*; D004945:Esophagoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry / Q000295:instrumentation / Q000379:methods; D008875:Middle Aged; D012189:Retrospective Studies
keywords: dysphagia; fluorography; swallowing study