title: Clinical experiences of NBI laryngoscope in diagnosis of laryngeal lesions.
abstract: Endoscopy is essential for the diagnosis and treatment of cancers derived from the larynx. However, a laryngoscope with conventional white light (CWL) has technical limitations in detecting small or superficial lesions on the mucosa. Narrow band imaging especially combined with magnifying endoscopy (ME) is useful for the detection of superficial squamous cell carcinoma (SCC) within the oropharynx, hypopharynx, and oral cavity. A total of 3675 patients who have come to the outpatient clinic and complained of inspiratory stridor, dyspnea, phonation problems or foreign body sensation, were enrolled in this study. We describe the glottic conditions of the patients. All 3675 patients underwent laryngoscopy equipped with conventional white light (CWL) and NBI system. 1149 patients received a biopsy process. And 1153 lesions were classified into different groups according to their histopathological results. Among all the 1149 patients, 346 patients (312 males, 34 females; mean age 62.2±10.5 years) were suspected of having a total of 347 precancerous or cancerous (T1 or T2 without lymphnode involvement) lesions of the larynx under the CWL. Thus, we expected to attain a complete vision of what laryngeal lesions look like under the NBI view of a laryngoscope. The aim was to develop a complete description list of each laryngeal conditions (e.g. polyps, papilloma, leukoplakia, etc.), which can serve as a criteria for further laryngoscopic examinations and diagnosis.
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, The Second Hospital, Jilin University 218 Ziqiang Street, Changchun 130041, Jilin Province, China.
authors.forename: Xinmeng
authors.initials: X
authors.lastname: Qi
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, The Second Hospital, Jilin University 218 Ziqiang Street, Changchun 130041, Jilin Province, China.
authors.forename: Dan
authors.initials: D
authors.lastname: Yu
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, The Second Hospital, Jilin University 218 Ziqiang Street, Changchun 130041, Jilin Province, China.
authors.forename: Xue
authors.initials: X
authors.lastname: Zhao
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, The Second Hospital, Jilin University 218 Ziqiang Street, Changchun 130041, Jilin Province, China.
authors.forename: Chunshun
authors.initials: C
authors.lastname: Jin
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Wuxi Fourth People' Hospital, Affiliated Hospital of Jiangnan University Wuxi 214000, Jiangsu Province, China.
authors.forename: Changling
authors.initials: C
authors.lastname: Sun
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, The Second Hospital, Jilin University 218 Ziqiang Street, Changchun 130041, Jilin Province, China.
authors.forename: Xueshibojie
authors.initials: X
authors.lastname: Liu
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, The Second Hospital, Jilin University 218 Ziqiang Street, Changchun 130041, Jilin Province, China.
authors.forename: Jinzhang
authors.initials: J
authors.lastname: Cheng
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, The Second Hospital, Jilin University 218 Ziqiang Street, Changchun 130041, Jilin Province, China.
authors.forename: Dejun
authors.initials: D
authors.lastname: Zhang
keywords: Narrow band imaging; diagnosis; endoscopy; laryngeal lesion