title: A systematic review of cervical cancer incidence and mortality in the Pacific Region.
abstract: This study provides the first systematic literature review of cervical cancer incidence and mortality as well as human papillomavirus (HPV) genotype prevalence among women with cervical cancer in the Pacific Island countries and territories. The cervical cancer burden in the Pacific Region is substantial, with age standardized incidence rates ranging from 8.2 to 50.7 and age standardized mortality rate from 2.7 to 23.9 per 100,000 women per year. The HPV genotype distribution suggests that 70-80% of these cancers could be preventable by the currently available bi- or quadrivalent HPV vaccines. There are only few comprehensive studies examining the epidemiology of cervical cancer in this region and no published data have hitherto described the current cervical cancer prevention initiatives in this region.
authors.affiliation: Department of Obstetrics and Gynaecology, Hvidovre Hospital, Denmark E-mail : jobel@dadlnet.dk.
authors.forename: J
authors.initials: J
authors.lastname: Obel
authors.forename: Y
authors.initials: Y
authors.lastname: Souares
authors.forename: D
authors.initials: D
authors.lastname: Hoy
authors.forename: W
authors.initials: W
authors.lastname: Baravilala
authors.forename: S M
authors.initials: SM
authors.lastname: Garland
authors.forename: S K
authors.initials: SK
authors.lastname: Kjaer
authors.forename: A
authors.initials: A
authors.lastname: Roth
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D003906:Developing Countries; D005260:Female; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D020380:Needs Assessment; D010139:Pacific Islands / Q000453:epidemiology; D030361:Papillomavirus Infections / Q000175:diagnosis / Q000453:epidemiology*; D018570:Risk Assessment; D016019:Survival Analysis; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology