title: Transient remission of childhood acute lymphoblastic and myeloid leukemia without any cytostatic treatment: 2 case reports and a review of literature.
abstract: Transient remissions (TRs) of acute leukemia without any antileukemic treatment are extremely rare events. We report 2 TRs of acute lymphoblastic leukemia and acute myeloid leukemia in a 2-year-old boy and a 12-year-old girl, respectively, both associated with red blood cells and platelets transfusions and infection. These 2 factors are frequently present in previously reported cases and could induce a stimulation of the immune system although the underlying mechanisms of TRs are still unknown.
authors.affiliation: *Unité d'Oncologie Pédiatrique, Service de Pédiatrie A †Service de Pédiatrie A, American Memorial Hospital, CHU Reims, Reims Cedex, France.
authors.forename: Claire
authors.initials: C
authors.lastname: Pluchart
authors.forename: Martine
authors.initials: M
authors.lastname: Munzer
authors.forename: Pierre
authors.initials: P
authors.lastname: Mauran
authors.forename: Michel
authors.initials: M
authors.lastname: Abély
mesh_terms: D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D017707:Erythrocyte Transfusion; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000276:immunology*; D008297:Male; D017713:Platelet Transfusion; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000276:immunology*; D012075:Remission, Spontaneous