title: Alternative methods for the detection of emerging marine toxins: biosensors, biochemical assays and cell-based assays.
abstract: The emergence of marine toxins in water and seafood may have a considerable impact on public health. Although the tendency in Europe is to consolidate, when possible, official reference methods based on instrumental analysis, the development of alternative or complementary methods providing functional or toxicological information may provide advantages in terms of risk identification, but also low cost, simplicity, ease of use and high-throughput analysis. This article gives an overview of the immunoassays, cell-based assays, receptor-binding assays and biosensors that have been developed for the screening and quantification of emerging marine toxins: palytoxins, ciguatoxins, cyclic imines and tetrodotoxins. Their advantages and limitations are discussed, as well as their possible integration in research and monitoring programs.
authors.affiliation: IRTA, Carretera Poble Nou km 5.5, 43540 Sant Carles de la Ràpita, Spain. laia.reverte@irta.cat.
authors.forename: Laia
authors.initials: L
authors.lastname: Reverté
authors.affiliation: IRTA, Carretera Poble Nou km 5.5, 43540 Sant Carles de la Ràpita, Spain. lucia.solino@irta.cat.
authors.forename: Lucía
authors.initials: L
authors.lastname: Soliño
authors.affiliation: IRTA, Carretera Poble Nou km 5.5, 43540 Sant Carles de la Ràpita, Spain. olga.carnicer@irta.cat.
authors.forename: Olga
authors.initials: O
authors.lastname: Carnicer
authors.affiliation: IRTA, Carretera Poble Nou km 5.5, 43540 Sant Carles de la Ràpita, Spain. jorge.diogene@irta.cat.
authors.forename: Jorge
authors.initials: J
authors.lastname: Diogène
authors.affiliation: IRTA, Carretera Poble Nou km 5.5, 43540 Sant Carles de la Ràpita, Spain. monica.campas@irta.cat.
authors.forename: Mònica
authors.initials: M
authors.lastname: Campàs
mesh_terms: D000818:Animals; D001681:Biological Assay / Q000379:methods*; D015374:Biosensing Techniques / Q000379:methods; D005506:Food Contamination / Q000032:analysis; D006801:Humans; D008387:Marine Toxins / Q000737:chemistry*; D017747:Seafood / Q000032:analysis
chemical_list: D008387:Marine Toxins