title: Samter's triad with aural involvement: a novel approach to management.
abstract: BACKGROUND
  Samter's triad is a well described condition manifesting as chronic rhinosinusitis with nasal polyposis, asthma and aspirin intolerance in a non-atopic individual. The underlying mechanism is still to be fully elucidated. However, aural disease has not been widely reported in these patients. In the few reported cases, most patients underwent major surgery with varying degrees of success.
  
  
  METHODS
  We report two Samter's triad patients with aural involvement. Both were successfully managed by conservative treatment, thus avoiding the need for major surgery. It appears that more Samter's triad patients may have aural disease than previously thought.
  
  
  CONCLUSIONS
  We report good outcomes with conservative treatment, which is relevant because aural disease tends to reoccur in these patients.
authors.affiliation: Department of Otolaryngology,St. Mary's Hospital Paddington, Imperial College Healthcare NHS Trust,London,UK.
authors.forename: P
authors.initials: P
authors.lastname: Sethukumar
authors.affiliation: Department of Otolaryngology,St. Mary's Hospital Paddington, Imperial College Healthcare NHS Trust,London,UK.
authors.forename: R
authors.initials: R
authors.lastname: Heywood
authors.affiliation: Department of Otolaryngology,St. Mary's Hospital Paddington, Imperial College Healthcare NHS Trust,London,UK.
authors.forename: A
authors.initials: A
authors.lastname: Narula
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D001241:Aspirin / Q000009:adverse effects; D001249:Asthma / Q000503:physiopathology / Q000628:therapy*; D002908:Chronic Disease; D004342:Drug Hypersensitivity / Q000209:etiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009298:Nasal Polyps / Q000503:physiopathology / Q000628:therapy*; D012852:Sinusitis / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D001241:Aspirin