title: The synthesis of head-to-tail cyclic sulfono-γ-AApeptides.
abstract: We report an efficient method for the preparation of unprecedented head-to-tail cyclic sulfono-γ-AApeptides. Following this method, a number of cyclic sequences bearing two to five subunits were efficiently synthesized. In addition, the X-ray crystal structure study of a three-membered cyclic sulfono-γ-AApeptide revealed a type II β-turn-like character.
authors.affiliation: Department of Chemistry, University of South Florida, 4202 E. Fowler Ave, Tampa, FL 33620, USA. jianfengcai@usf.edu.
authors.forename: Haifan
authors.initials: H
authors.lastname: Wu
authors.forename: Fengyu
authors.initials: F
authors.lastname: She
authors.forename: Wenyang
authors.initials: W
authors.lastname: Gao
authors.forename: Austin
authors.initials: A
authors.lastname: Prince
authors.forename: Yaqiong
authors.initials: Y
authors.lastname: Li
authors.forename: Lulu
authors.initials: L
authors.lastname: Wei
authors.forename: Allison
authors.initials: A
authors.lastname: Mercer
authors.forename: Lukasz
authors.initials: L
authors.lastname: Wojtas
authors.forename: Shengqian
authors.initials: S
authors.lastname: Ma
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Cai
mesh_terms: D000603:Amino Acids, Sulfur / Q000737:chemistry*; D018360:Crystallography, X-Ray; D003500:Cyclization; D015394:Molecular Structure; D010456:Peptides, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry; D057786:Peptidomimetics / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000603:Amino Acids, Sulfur; D010456:Peptides, Cyclic; D057786:Peptidomimetics