title: [Initial scotomas in normal tension glaucoma].
abstract: OBJECTIVE
  To investigate risk factors for initial visual field pattern in normal tension glaucoma (NTG).
  
  
  METHODS
  We studied 107 subjects, who underwent 24-2 or 30-2 Swedish interactive threshold algorithm standard visual fields as part of a multicenter study of newly diagnosed NTG patients. Only the eyes with initial parafoveal scotoma (IPFS) or initial nasal step (INS) Were included. IPFS was defined as a glaucomatous visual field (VF) defect in 1 hemifield (≥ 3 adjacent points with p < 5% within the central 10 degrees of fixation, ≥ 1 point with p < l% lying at the innermost paracentral points, and no VF abnormality outside the central 10 degrees). INS was defined in 1 hemifield (≥ 3 adjacent points with p < 5% in the nasal periphery outside 10 degrees of fixation, the nasal- most point with p < 1%, and no VF abnormality within the central 10 degrees). Clinical characteristics were compared between the 2 groups.
  
  
  RESULTS
  Mean untreated intraocular pressure (IOP) (14.0 ± 1.3 vs. 16.0 ± l.4 mmHg; p = 0.0102) was significantly lower in patients with an IPFS than in patients with an INS. There were no significant differences in age (p = 0.6487) or spherical equivalent (p = 0.7561).
  
  
  CONCLUSIONS
  Initial visual field pattern of NTG is influenced by untreated IOP level.
authors.forename: Shiro
authors.initials: S
authors.lastname: Mizoue
authors.forename: Aiko
authors.initials: A
authors.lastname: Iwase
authors.forename: Shun
authors.initials: S
authors.lastname: Matsumoto
authors.forename: Keiji
authors.initials: K
authors.lastname: Yoshikawa
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005901:Glaucoma / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012607:Scotoma / Q000209:etiology*; D014065:Tonometry, Ocular / Q000379:methods; D014794:Visual Fields / Q000502:physiology*