title: [State of specific and natural immunobiological resistance in patients with colorectal cancer in conditions of obturation of the colon].
abstract: Estimation of the immune state was performed in 57 patients, suffering colorectal cancer (CRC) with impassability of large bowel (ILB) in compensated stage (in 30) and subcompensated (in 27). In all the patients immunosuppression was revealed, in ILB in a compensation stage activation of proinflammatory and antiinflammatory citokines--mediators of immune system, while in LIL in a subcompensation stage and in progressing of CRC--inhibition of antiblastomic mediators on background of significant rising of the problastomic citokines, what may have a prognostic significance for optimization of pathogenetic therapy in such patients.
authors.forename: V V
authors.initials: VV
authors.lastname: Boĭko
authors.forename: I A
authors.initials: IA
authors.lastname: Kryvoruchko
authors.forename: B I
authors.initials: BI
authors.lastname: Zhukov
authors.forename: A S
authors.initials: AS
authors.lastname: Moiseienko
authors.forename: S A
authors.initials: SA
authors.lastname: Andreieshchev
mesh_terms: D000208:Acute Disease; D000368:Aged; D016022:Case-Control Studies; D003106:Colon / Q000473:pathology; D015179:Colorectal Neoplasms / Q000097:blood / Q000150:complications / Q000276:immunology*; D016207:Cytokines / Q000097:blood; D006801:Humans; D007111:Immunity, Cellular; D056724:Immunity, Humoral; D007113:Immunity, Innate; D007415:Intestinal Obstruction / Q000097:blood / Q000209:etiology / Q000276:immunology*; D008875:Middle Aged; D011237:Predictive Value of Tests
chemical_list: D016207:Cytokines