title: Prenatal Diagnosis of a Persistent Fifth Aortic Arch, Pulmonary-to-Systemic type: An Unusual Association with Evolving Aortic Coarctation.
abstract: Persistent fifth arch (PFA) is a rare anomaly that is often underdiagnosed and missed. Different PFA types that have been reported in the literature are systemic-to-systemic type (most common), systemic-to-pulmonary artery (PA), and PA-to-systemic types. The designations of systemic-to-PA or PA-to-systemic are based on if the PFA is a source of PA or systemic blood flow, respectively, in the setting of critical proximal obstruction (pulmonary atresia or aortic atresia). This case describes an unusual PFA, which connects the distal PA to distal ascending aorta; however, it is not associated with critical proximal obstruction, and while it appeared to be an incidental finding in early gestation, progressive serial distal obstruction of the left fourth arch was seen to develop. This case highlights that prenatal diagnosis of PFA is possible and that once a diagnosis is made, serial fetal echocardiograms should be performed to evaluate for evolving lesions.
authors.affiliation: NY University Langone Medical Center, New York City, New York.
authors.forename: Puneet
authors.initials: P
authors.lastname: Bhatla
authors.forename: Sujata
authors.initials: S
authors.lastname: Chakravarti
authors.forename: Leon
authors.initials: L
authors.lastname: Axel
authors.forename: Achi
authors.initials: A
authors.lastname: Ludomirsky
authors.forename: Giselle
authors.initials: G
authors.lastname: Revah
mesh_terms: D001011:Aorta / Q000002:abnormalities* / Q000000981:diagnostic imaging* / Q000601:surgery; D001017:Aortic Coarctation / Q000000981:diagnostic imaging* / Q000601:surgery; D001018:Aortic Diseases / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D005260:Female; D006330:Heart Defects, Congenital / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D011247:Pregnancy; D011651:Pulmonary Artery / Q000002:abnormalities / Q000000981:diagnostic imaging*; D016216:Ultrasonography, Prenatal
keywords: congenital heart disease; fetal echocardiography; persistent fifth arch