title: [Experimental estimation of application efficacy of wound coverings as a means of conservative therapy of local radiation burns formed at combined radiation injures].
abstract: The study was aimed at experimental evaluating the efficacy of experimental wound collagen coverings "Sangvikol", "Gemasept", "Kolotsil" and "Biatravm" for treatment of deep radiation burns which form at combined radiation injures. The combined radiation injures were modeled by consecutive local X-ray radiation of skin at a dose of 120 Gy and the total whole body gamma-irradiation from a source of 137Cs at a dose of4 Gy. It is established that wound collagen coverings are well modeled on a wound, absorb excess exudate, maintain optimum humidity in a wound; protect a wound from infection, and medicinal fillers contribute to the activation of reparative processes in the irradiated skin. Wound coverings do not require frequent dressings and more effectively prevent post-radiation depression recovery processes in irradiated skin than ointments.
authors.forename: N I
authors.initials: NI
authors.lastname: Zargarova
authors.forename: A N
authors.initials: AN
authors.lastname: Grebeniuk
authors.forename: V I
authors.initials: VI
authors.lastname: Legeza
mesh_terms: D000818:Animals; D002056:Burns / Q000188:drug therapy* / Q000473:pathology; D005720:Gamma Rays; D006801:Humans; D008297:Male; D011832:Radiation Injuries / Q000188:drug therapy* / Q000473:pathology; D011837:Radiation-Protective Agents / Q000008:administration & dosage*; D051381:Rats; D014916:Whole-Body Irradiation; D014945:Wound Healing / Q000187:drug effects* / Q000528:radiation effects
chemical_list: D011837:Radiation-Protective Agents