title: Regional differences in heart failure with preserved ejection fraction trials: when nephrology meets cardiology but east does not meet west.
authors.affiliation: From Inserm, Centre d'Investigations Cliniques-Plurithématique 1433 and Inserm U1116, Nancy, France (P.R., F.Z.); CHU Nancy, Département de Cardiologie, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, Nancy, France (P.R., F.Z.); Université de Lorraine, Nancy, France (P.R., F.Z.); and INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R., F.Z.). p.rossignol@chu-nancy.fr.
authors.forename: Patrick
authors.initials: P
authors.lastname: Rossignol
authors.affiliation: From Inserm, Centre d'Investigations Cliniques-Plurithématique 1433 and Inserm U1116, Nancy, France (P.R., F.Z.); CHU Nancy, Département de Cardiologie, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, Nancy, France (P.R., F.Z.); Université de Lorraine, Nancy, France (P.R., F.Z.); and INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R., F.Z.).
authors.forename: Faiez
authors.initials: F
authors.lastname: Zannad
mesh_terms: D001562:Benzimidazoles / Q000627:therapeutic use*; D001713:Biphenyl Compounds / Q000627:therapeutic use*; D005260:Female; D005464:Fluorobenzenes / Q000627:therapeutic use*; D005843:Geography; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology*; D006801:Humans; D038622:Internationality; D000077405:Irbesartan; D008297:Male; D000451:Mineralocorticoid Receptor Antagonists / Q000627:therapeutic use*; D010361:Patients; D011743:Pyrimidines / Q000627:therapeutic use*; D000068718:Rosuvastatin Calcium; D013148:Spironolactone / Q000627:therapeutic use*; D013318:Stroke Volume / Q000502:physiology*; D013449:Sulfonamides / Q000627:therapeutic use*; D013777:Tetrazoles / Q000627:therapeutic use*
chemical_list: D001562:Benzimidazoles; D001713:Biphenyl Compounds; D005464:Fluorobenzenes; D000451:Mineralocorticoid Receptor Antagonists; D011743:Pyrimidines; D013449:Sulfonamides; D013777:Tetrazoles; D013148:Spironolactone; D000068718:Rosuvastatin Calcium; D000077405:Irbesartan; C081643:candesartan
keywords: Editorials; aldosterone; clinical trials as topic; heart failure; kidney function; mineralocorticoids; ventricular function, left