title: Brain Metastases of Papillary Thyroid Carcinoma with Horner's Syndrome.
abstract: Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy and has relatively favorable prognosis. Blood-borne metastases of PTC are very rare among the thyroid malignancies. Moreover a case of blood-borne central nervous system metastasized PTC with only unilateral Horner's syndrome, and without any abnormalities in laboratory or physical examinations has not been described before. A 53-year-old female patient had been managed in ophthalmologic clinic due to vague symptoms of right monocular blurred vision with eye dryness for 3 months, but showed no signs of improvement. So it was performed a magnetic resonance imaging and magnetic resonance angiography to evaluate the possibilities of cerebral lesion. And a left frontal mass was incidentally found, and the tumor turned out to be a PTC that had metastasized to brain, regional lymph node, cervical, thoracic spine, and lung. We describe a PTC with extraordinary initial symptoms that metastasized to an unusual site. We recommend that if a papillary thyroid tumor with unusual symptoms or at an advanced stage is found, further investigation should be performed for distant metastasis.
authors.affiliation: Department of Neurosurgery, College of Medicine, The Catholic University of Korea, Yeouido St. Mary's Hospital, Seoul, Korea.
authors.forename: Sung-Hoon
authors.initials: SH
authors.lastname: Cho
authors.affiliation: Department of Neurosurgery, College of Medicine, The Catholic University of Korea, Yeouido St. Mary's Hospital, Seoul, Korea.
authors.forename: Sang-Hyo
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Department of Neurosurgery, College of Medicine, The Catholic University of Korea, Yeouido St. Mary's Hospital, Seoul, Korea.
authors.forename: Jung-Hwan
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Department of Neurosurgery, College of Medicine, The Catholic University of Korea, Yeouido St. Mary's Hospital, Seoul, Korea.
authors.forename: Won-Il
authors.initials: WI
authors.lastname: Joo
authors.affiliation: Department of Neurosurgery, College of Medicine, The Catholic University of Korea, Yeouido St. Mary's Hospital, Seoul, Korea.
authors.forename: Chung-Kee
authors.initials: CK
authors.lastname: Chough
authors.affiliation: Department of Neurosurgery, College of Medicine, The Catholic University of Korea, Yeouido St. Mary's Hospital, Seoul, Korea.
authors.forename: Hae-Kwan
authors.initials: HK
authors.lastname: Park
authors.affiliation: Department of Neurosurgery, College of Medicine, The Catholic University of Korea, Yeouido St. Mary's Hospital, Seoul, Korea.
authors.forename: Kyung-Jin
authors.initials: KJ
authors.lastname: Lee
authors.affiliation: Department of Neurosurgery, College of Medicine, The Catholic University of Korea, Yeouido St. Mary's Hospital, Seoul, Korea.
authors.forename: Hyoung-Kyun
authors.initials: HK
authors.lastname: Rha
keywords: Horner syndrome; Metastases; Papillary thyroid carcinoma; Treatment