title: A clinical study on the efficacy of hydroxyapatite - Bioactive glass composite granules in the management of periodontal bony defects.
abstract: BACKGROUND
  In periodontal regeneration, several alloplastic materials are being used with a goal to reconstruct new osseous tissue in the infrabony defect sites. The present study was undertaken to evaluate the efficacy of hydroxyapatite-bioactive glass (HA:BG) composite granules in the management of periodontal bony defects.
  
  
  METHODS
  A randomized control study was conducted. Subjects with infrabony defects were divided into three groups. Test Group 1 (n = 10): Defect site was treated with HA:BG, with a biodegradable membrane. Test Group 2 (n = 10): Defect site was treated with HAP, with a biodegradable membrane. Control group (n = 10): Defect site was treated with open flap debridement with a biodegradable membrane.
  
  
  RESULTS
  The healing of defects was uneventful and free of any biological complications. The gain in clinical attachment level, reduction of probing pocket depth, and defect fill were statistically significant in all three groups. TG1 sites showed significant defect fill than TG2 and CG sites.
  
  
  CONCLUSIONS
  The performance of HA:BG was better compared to HAP and open flap debridement for the reconstruction of infrabony defects.
authors.affiliation: Department of Periodontics, Guru Nanak Institute of Dental Sciences and Research, Panihati, Kolkata, India.
authors.forename: Tirthankar
authors.initials: T
authors.lastname: Debnath
authors.affiliation: Department of Periodontics, Guru Nanak Institute of Dental Sciences and Research, Panihati, Kolkata, India.
authors.forename: Abhijit
authors.initials: A
authors.lastname: Chakraborty
authors.affiliation: Department of Periodontics, Guru Nanak Institute of Dental Sciences and Research, Panihati, Kolkata, India.
authors.forename: Tamal Kanti
authors.initials: TK
authors.lastname: Pal
keywords: Alloplastic bone graft; calcium hydroxyapatite and bioactive glass; periodontal bony defect