title: [Toxoplasma gondii infection status in abnormal pregnancy women].
abstract: OBJECTIVE
  To investigate the relationship between Toxoplasma gondii (TOX) infection and abnormal pregnancy outcomes.
  
  
  METHODS
  A total of 126 cases of abnormal pregnancy women in the Department of Obstetrics and Gynecology, the Fourth People' s Hospital of Langfang from March to December 2013 were chosen as an experimental group, and 263 cases of normal pregnancy women of childbearing age as a control group. The TOX-IgM and -IgG antibodies were detected by ELISA. The data in the two groups were processed and analyzed by SPSS13.0.
  
  
  RESULTS
  The positive rates of TOX-IgM, -IgG in 126 cases of abnormal pregnancy women were 7.94% and 19.84% respectively, and 1.90% and 8.75% in the control group respectively, and there were significant differences between them (χ2IgM = 6.82, χ2IgG = 9.70, both P <0.01). The positive rates of TOX-IgM, -IgG in the normal pregnancy women were lower than those in 4 sub-groups of abnormal pregnancy women, and all the differences were statistically significant (χ2 spontaneous abortion = 10.40, χ2 premature delivery = 9.03 χ2 embryo damage = 4.32, χ2 birth defet = 4.04, all P< 0.05). However, the TOX-IgM, -IgG positive rates in the 4 sub-groups of abnormal pregnancy women had no statistically significant difference (P > 0.05).
  
  
  CONCLUSIONS
  TOX infection could cause serious abnormal pregnancy outcomes. Therefore, the comprehensive control measures should be strengthened.
authors.forename: Shu-fang
authors.initials: SF
authors.lastname: Zhang
authors.forename: Ren-hao
authors.initials: RH
authors.lastname: Song
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000097:blood / Q000503:physiopathology*; D011256:Pregnancy Outcome; D014122:Toxoplasma / Q000276:immunology / Q000502:physiology*; D014123:Toxoplasmosis / Q000097:blood / Q000503:physiopathology*; D055815:Young Adult
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M