title: Demonstration that a case of human alveolar echinococcosis in Minnesota in 1977 was caused by the N2 strain.
abstract: Alveolar echinococcosis is the most serious helminthic zoonosis of the northern hemisphere affecting humans. The causative agent, Echinococcus multilocularis, occurs in geographically distinct strains that can be distinguished based on sequence variations of mitochondrial genes and nuclear microsatellite targets. This report finds that the human case of Alveolar echinococcosis occurring in Minnesota in 1977 was caused by the N2 haplotype described previously; the N2 haplotype is distinct from European and Asian isolates of the parasite and is restricted to the central region of North America.
authors.affiliation: Department of Veterinary Clinical and Diagnostic Sciences, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada; Department of Ecosystem and Public Health, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
authors.forename: Claudia
authors.initials: C
authors.lastname: Klein
authors.affiliation: Department of Veterinary Clinical and Diagnostic Sciences, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada; Department of Ecosystem and Public Health, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada amassolo@ucalgary.ca.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Massolo
mesh_terms: D000818:Animals; D004272:DNA, Mitochondrial / Q000235:genetics; D004444:Echinococcosis, Hepatic / Q000453:epidemiology / Q000469:parasitology*; D048210:Echinococcus multilocularis / Q000145:classification* / Q000235:genetics; D006239:Haplotypes; D006801:Humans; D018895:Microsatellite Repeats / Q000235:genetics; D008910:Minnesota / Q000453:epidemiology
chemical_list: D004272:DNA, Mitochondrial