title: Locoregional treatment of breast cancer during pregnancy.
abstract: The management of patients with breast cancer during pregnancy is very demanding and it should be better performed in highly qualified and experienced centers. Referral to institutes and physicians trained in this special clinical scenario allows reducing the risk of both overtreating and undertreating the patients. Moreover, patients can receive appropriate information regarding safety of treatments without old-fashionedtaboo. The purpose of the current paper is to discuss the main issues concerning surgical management and in general locoregional treatment of patients diagnosed with breast cancer and treated during gestation, focusing on those women who chose to continue their pregnancy. We cover the issues regarding type of breast surgery, radiation therapy, immediate reconstruction during mastectomy, and management of the axilla.
authors.affiliation: Division of Breast Surgery, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Toesca
authors.affiliation: Division of Breast Surgery, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy.
authors.forename: Oreste
authors.initials: O
authors.lastname: Gentilini
authors.affiliation: Department of Gynecological Oncology, European Institute of Oncology, Milan, Italy.
authors.forename: Fedro
authors.initials: F
authors.lastname: Peccatori
authors.affiliation: Department of Medicine, BrEAST Data Centre, Institut Jules Bordet, Université Libre de Bruxelles, 1000 Brussels, Belgium.
authors.forename: Hatem A
authors.initials: HA
authors.lastname: Azim
authors.affiliation: Multidisciplinary Breast Center, Leuven Cancer Institute (LKI), UZ Gasthuisberg, Katholieke Universiteit Leuven, Leuven, Belgium.
authors.forename: Frederic
authors.initials: F
authors.lastname: Amant
keywords: Breast cancer; Chemotherapy; Pregnancy; Radiation therapy