title: Executive summary of the consensus document on the management of renal disease in HIV-infected patients.
abstract: The aim of this article is to update the 2010 recommendations on the evaluation and management of renal disease in HIV-infected patients. Renal function should be monitored in all HIV-infected patients. The basic renal work-up should include measurements of serum creatinine, estimated glomerular filtration rate by CKD-EPI, urine protein-to-creatinine ratio, and urinary sediment. Tubular function tests should include determination of serum phosphate levels and urine dipstick for glucosuria. In the absence of abnormal values, renal screening should be performed annually. In patients treated with tenofovir or with risk factors for chronic kidney disease (CKD), more frequent renal screening is recommended. In order to prevent disease progression, potentially nephrotoxic antiretroviral drugs are not recommended in patients with CKD or risk factors for CKD. The document provides indications for renal biopsy and advises on the optimal time for referral of a patient to the nephrologist. The indications for and evaluation and management of dialysis and renal transplantation are also addressed.
authors.forename: José Luis
authors.initials: JL
authors.lastname: Górriz
authors.forename: Félix
authors.initials: F
authors.lastname: Gutiérrez
authors.forename: Joan Carles
authors.initials: JC
authors.lastname: Trullas
authors.forename: Piedad
authors.initials: P
authors.lastname: Arazo
authors.forename: Jose Ramón
authors.initials: JR
authors.lastname: Arribas
authors.forename: Guillermina
authors.initials: G
authors.lastname: Barril
authors.forename: Miguel
authors.initials: M
authors.lastname: Cervero
authors.forename: Frederic
authors.initials: F
authors.lastname: Cofan
authors.forename: Pere
authors.initials: P
authors.lastname: Domingo
authors.forename: Vicente
authors.initials: V
authors.lastname: Estrada
authors.forename: Xavier
authors.initials: X
authors.lastname: Fulladosa
authors.forename: Maria José
authors.initials: MJ
authors.lastname: Galindo
authors.forename: Silvia
authors.initials: S
authors.lastname: Gracia
authors.forename: Jose Antonio
authors.initials: JA
authors.lastname: Iribarren
authors.forename: Hernando
authors.initials: H
authors.lastname: Knobel
authors.forename: Jose
authors.initials: J
authors.lastname: Lopez-Aldeguer
authors.forename: Fernando
authors.initials: F
authors.lastname: Lozano
authors.forename: Alberto
authors.initials: A
authors.lastname: Martínez-Castelao
authors.forename: Esteban
authors.initials: E
authors.lastname: Martinez
authors.forename: Maria A
authors.initials: MA
authors.lastname: Mazuecos
authors.forename: Celia
authors.initials: C
authors.lastname: Miralles
authors.forename: Rosario
authors.initials: R
authors.lastname: Montañes
authors.forename: Eugenia
authors.initials: E
authors.lastname: Negredo
authors.forename: Rosario
authors.initials: R
authors.lastname: Palacios
authors.forename: María Jesús
authors.initials: MJ
authors.lastname: Pérez-Elías
authors.forename: Joaquin
authors.initials: J
authors.lastname: Portilla
authors.forename: Manuel
authors.initials: M
authors.lastname: Praga
authors.forename: Carlos
authors.initials: C
authors.lastname: Quereda
authors.forename: Antonio
authors.initials: A
authors.lastname: Rivero
authors.forename: Juan M
authors.initials: JM
authors.lastname: Santamaria
authors.forename: Jose
authors.initials: J
authors.lastname: Sanz
authors.forename: Jesús
authors.initials: J
authors.lastname: Sanz
authors.forename: José María
authors.initials: JM
authors.lastname: Miró
mesh_terms: D000740:Anemia / Q000209:etiology / Q000628:therapy; D019380:Anti-HIV Agents / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000628:therapy; D015897:Comorbidity; D048909:Diabetes Complications / Q000453:epidemiology / Q000628:therapy; D019468:Disease Management; D018450:Disease Progression; D004347:Drug Interactions; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology; D006525:Hepatitis, Viral, Human / Q000453:epidemiology; D006801:Humans; D006949:Hyperlipidemias / Q000188:drug therapy / Q000453:epidemiology; D006973:Hypertension / Q000188:drug therapy / Q000453:epidemiology; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use; D007677:Kidney Function Tests; D016030:Kidney Transplantation; D009398:Nephrology; D050177:Overweight / Q000453:epidemiology; D016035:Pancreas Transplantation; D012017:Referral and Consultation; D051436:Renal Insufficiency, Chronic / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D017582:Renal Replacement Therapy; D016482:Urinalysis
chemical_list: D019380:Anti-HIV Agents; D007166:Immunosuppressive Agents