title: Stealing VEGF from thy neighbor.
abstract: The distribution and patterning of blood vessels is controlled by vascular endothelial growth factor (VEGF), which is precisely regulated throughout its life cycle. Okabe et al. show that VEGF is titrated away from the endothelium by adjacent neurons via endocytosis, regulating density and trajectory of blood vessels.
authors.affiliation: Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, 615 Charles E. Young Drive South, Los Angeles, CA 90095, USA.
authors.forename: Courtney K
authors.initials: CK
authors.lastname: Domigan
authors.affiliation: Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, 615 Charles E. Young Drive South, Los Angeles, CA 90095, USA. Electronic address: arispe@mcdb.ucla.edu.
authors.forename: M Luisa
authors.initials: ML
authors.lastname: Iruela-Arispe
mesh_terms: D000818:Animals; D018919:Neovascularization, Physiologic; D009474:Neurons / Q000378:metabolism*; D012160:Retina / Q000254:growth & development*; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism*
chemical_list: D042461:Vascular Endothelial Growth Factor A