title: Vertical Guided Bone Regeneration using Titanium-reinforced d-PTFE Membrane and Prehydrated Corticocancellous Bone Graft.
abstract: Guided bone regeneration (GBR) standard protocols call for filling the space underneath the membrane with autogenous bone or a mixture composed of autogenous bone particles and allogeneic bone tissue or heterologous biomaterials. This work describes the case of a GBR performed to restore a vertical bone defect with simultaneous placement of a dental implant in the posterior mandible that was carried out using a high density d-PTFE membrane and corticocancellous porcine-derived bone without the addition of any autogenous bone. Bone regeneration was assessed by histological analysis of a biopsy sample collected from the grafted site nine months after the surgery. Intraoral radiographs taken at follow-up visits showed complete maintenance of the peri-implant bone levels for up to two years after prosthesis delivery. The regenerated site successfully supported functional loading of the implant. The present case report suggests that the use of a heterologous bone substitute alone to restore a vertical defect in a GBR procedure can be as effective as the standard protocol, while avoiding the drawbacks associated with a second surgical site opening.
authors.affiliation: Department of Biomedical and Neuromotorial Science, University of Bologna, Bologna, Italy. Private Practice, Mantova (MN), Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Cucchi
authors.affiliation: Department of Neuroscience, University of Padova, Padova, Italy. Private Practice, Trento (TN), Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Ghensi
keywords: Guided bone regeneration; heterologous biomaterials; vertical bone augmentation