title: Radical scavenging activities of flavonoids from roots of Akschindlium godefroyanum.
abstract: Chemical constituents of crude ethyl acetate extract of roots of Akschindlium godefroyanum (Kuntze) H. Ohashi were investigated and seven flavonoids were isolated. Their structures were identified based on spectroscopic methods as well as by comparison with spectral data reported in the literature as six flavanonols and a flavonol including 7,4'-dihydroxy-5,3'-dimethoxyflavanonol (1), neophellamuretin (2), taxifolin (3), erycibenin D (4), geraldol (5), fustin (6) and garbanzol (7). Compounds 2, 4 and 7 were found in the genus Akschindlium for the first time. Compounds 3, 5 and 6 appeared to have free radical scavenging activities using DPPH assay with IC50 of 21, 40 and 15 μg/mL, respectively.
authors.affiliation: a Program of Science, Faculty of Education, Sisaket Rajabhat University , Sisaket 33000 , Thailand.
authors.forename: Kanokkarn
authors.initials: K
authors.lastname: Saejueng
authors.forename: Natcha
authors.initials: N
authors.lastname: Panthama
mesh_terms: D007887:Fabaceae / Q000737:chemistry*; D044948:Flavonols / Q000494:pharmacology*; D016166:Free Radical Scavengers / Q000494:pharmacology*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry*
chemical_list: D044948:Flavonols; D016166:Free Radical Scavengers; D010936:Plant Extracts
keywords: Akschindlium godefroyanum; DPPH; flavonoids