title: Copper-catalyzed oxidative homo- and cross-coupling of Grignard reagents using diaziridinone.
abstract: Transition-metal-catalyzed cross-coupling reactions are among the most powerful synthetic transformations. This paper describes an efficient copper-catalyzed homo- and cross-coupling of Grignard reagents with di-tert-butyldiaziridinone as oxidant under mild conditions, giving the coupling products in good to excellent yields. The reaction process has a broad substrate scope and is also effective for the C(sp)-C(sp(3)) coupling.
authors.affiliation: Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States.
authors.forename: Yingguang
authors.initials: Y
authors.lastname: Zhu
authors.affiliation: Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States.
authors.forename: Tao
authors.initials: T
authors.lastname: Xiong
authors.affiliation: Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States.
authors.forename: Wenyong
authors.initials: W
authors.lastname: Han
authors.affiliation: Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States.
authors.forename: Yian
authors.initials: Y
authors.lastname: Shi
mesh_terms: D000818:Animals; D001388:Aziridines / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003300:Copper / Q000737:chemistry*; D007202:Indicators and Reagents; D015394:Molecular Structure; D010084:Oxidation-Reduction
chemical_list: D001388:Aziridines; D007202:Indicators and Reagents; C527442:di-tert-butyldiaziridinone; D003300:Copper