title: [A meta-analysis of surgery treatment of chronic pancreatitis with an inflammatory mass in the head of pancreas: duodenum-preserving pancreatic head resection versus pancreatoduodenectomy].
abstract: OBJECTIVE
  To compare the safety and effectiveness of DPPHR with PPPD/PD for treating chronic pancreatitis with an inflammatory mass in the head of pancreas.
  
  
  METHODS
  The relative data bases such as Medline, EMBase, Biosis, COCHRANE Library, Science Citation Index, SinoMed, Chinese Journal Full-text Database, Wangfang, CNKI were searched systematically, researchers selected randomized controlled trials (RCT) and prospective clinical controlled trials (CCT) . The assessment of the bias risk of the included trials was according to the assessing tools suggested by Cochrane Handbook 5.1. The Review Manage 5.2 was used to perform the statistical analysis.
  
  
  RESULTS
  In total, 5 RCTs and 2 CCTs were included, 381 patients involved. Comparing with PPPD/PD procedure, DPPHR has no significant difference in terms of the mortality of perioperative period (RD = 0.01, P = 0.51), the incidence of bleeding (RD = -0.01, P = 0.72), pancreatic fistula(RD = -0.01, P = 0.59) and delayed gastric emptying (RD = -0.15, P = 0.10), the ration of complete pain relief after operation (RR = 1.06, P = 0.32) and the score of global quality of life (WMD = 10.31, P = 0.19).While DPPHR had significant superiorities in terms of the total morbidity of perioperative period (RR = 0.60, P = 0.008), the duration of the operations(WMD = -71.60, P = 0.03), the postoperative hospitalization duration(WMD = -3.95, P < 0.01), weight gain(WMD = 3.68, P < 0.01), occupational rehabilitation after the operations (RR = 1.38, P = 0.008).
  
  
  CONCLUSIONS
  In terms of reducing the morbidity of perioperative period, shortening the duration of the operations and the postoperative hospitalization duration, weight gain, occupational rehabilitation after the operations, the DPPHR is more favorable for improving patients' life qualities comparing with PPPD/PD.
authors.affiliation: Department of Hepatobilary Surgery, the Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
authors.forename: Kangyi
authors.initials: K
authors.lastname: Jiang
authors.forename: Ke
authors.initials: K
authors.lastname: Wu
authors.forename: Yuping
authors.initials: Y
authors.lastname: Liao
authors.affiliation: Email: bing_tu@163.com.
authors.forename: Bing
authors.initials: B
authors.lastname: Tu
mesh_terms: D004386:Duodenum / Q000601:surgery; D006801:Humans; D010179:Pancreas / Q000601:surgery; D010180:Pancreatectomy / Q000379:methods; D016577:Pancreaticoduodenectomy / Q000379:methods*; D050500:Pancreatitis, Chronic / Q000601:surgery*; D011446:Prospective Studies; D011788:Quality of Life