title: Tobacco smoking and alcohol consumption as risk factors for site-specific intraoral epithelial dysplasia.
abstract: OBJECTIVE
  The aim of the present study was to evaluate the role of tobacco and alcohol as possible risk factors for oral epithelial dysplasia in the various oral subsites.
  
  
  METHODS
  Data were gathered from 630 patients with oral epithelial dysplasia in the United Arab Emirates between 1997 and 2007. Odds ratios for oral epithelial dysplasia at various oral subsites were estimated using multiple logistic regression for each level of exposure of interest.
  
  
  RESULTS
  The results showed that in males, oral epithelial dysplasia of the labial mucosa and floor of the mouth were strongly associated with tobacco smoking. In females, oral epithelial dysplasia of the floor of the mouth and tongue were the sites associated with tobacco smoking. Alcohol was not a significant determinant of the sites of oral epithelial dysplasia in either sex.
  
  
  CONCLUSIONS
  Tobacco smoking has a significant role in determining the oral epithelial dysplasia subsites, but alcohol consumption is not a risk factor for oral epithelial dysplasia sites.
authors.affiliation: Department of Surgical Sciences, College of Dentistry, Ajman University of Science and Technology, Ajman, United Arab Emirates. mjaber4@hotmail.com
authors.forename: Mohamed Abdullah
authors.initials: MA
authors.lastname: Jaber
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000428:Alcohol Drinking / Q000453:epidemiology*; D000434:Alcoholic Beverages / Q000145:classification / Q000706:statistics & numerical data; D001515:Beer / Q000145:classification / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008048:Lip Neoplasms / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009060:Mouth Floor / Q000473:pathology; D009061:Mouth Mucosa / Q000473:pathology*; D009062:Mouth Neoplasms / Q000453:epidemiology*; D011230:Precancerous Conditions / Q000453:epidemiology*; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000453:epidemiology*; D062789:Tobacco Products / Q000145:classification / Q000706:statistics & numerical data; D014062:Tongue Neoplasms / Q000453:epidemiology; D014479:United Arab Emirates / Q000453:epidemiology; D014920:Wine / Q000145:classification / Q000706:statistics & numerical data; D055815:Young Adult
keywords: alcohol; mouth; oral epithelial dysplasia; risk factor; tobacco