title: [Research progress of interaction between Toxoplasma gondii rhoptry proteins and host cells].
abstract: Rhoptry proteins are the major virulence factors of Toxoplasma gondii. They locate in different parts of the host cells, and can affect the membrane, cytoskeleton structure and active factors of the host cells, so as to block the cell intrinsic defense mechanisms of the host, and let T. gondii invade, parasitize and proliferate in the host successfully. The function and ac- tion mode of rhoptry proteins reflect the pathogenic mechanism of T. gondii, which holds great significance to looking for toxoplasmosis drug targets and developing molecule vaccines. This paper reviews the research progess of the interaction between rhoptry proteins of T. gondii and host cells.
authors.forename: Gui-hua
authors.initials: GH
authors.lastname: Zhao
authors.forename: Shu-xia
authors.initials: SX
authors.lastname: Yin
authors.forename: Kun
authors.initials: K
authors.lastname: Yin
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D006790:Host-Parasite Interactions; D021381:Protein Transport; D015800:Protozoan Proteins / Q000378:metabolism*; D015398:Signal Transduction; D014122:Toxoplasma / Q000378:metabolism* / Q000502:physiology
chemical_list: D015800:Protozoan Proteins