title: Pathogenic microbial amyloids: Their function and the host response.
abstract: Functional microbial amyloids are ubiquitous in nature and some contribute to the pathogenesis of infectious diseases. Three pathogenic microbial amyloids are compared and their contribution to the disease process explained. The recent demonstration and visualization of fungal amyloid in human invasive candidiasis is discussed. Moreover, the binding of host serum amyloid P component toCandidafunctional amyloid in invasive human disease is presented in light of its possible role of masking fungi from the host defenses.
authors.affiliation: Department of Biology, Brooklyn College of City University of New York, Brooklyn, NY.
authors.forename: Mc
authors.initials: M
authors.lastname: Garcia
authors.affiliation: Department of Medicine, University of Arizona, Tucson, AZ.
authors.forename: Pn
authors.initials: P
authors.lastname: Lipke
authors.forename: Sa
authors.initials: S
authors.lastname: Klotz
keywords: Amyloid; Candida Als proteins; Candida albicans; Candidiasis; Functional amyloid; Fungal amyloid; Serum amyloid P component; curli; merozoite surface protein 2; microbial adherence