title: Surgical hardware-related iatrogenic venous compression syndrome.
abstract: Deep vein thrombosis related to immobilization is a common and extensively studied disorder, particularly in hospitalized patients. However, the phenomenon of iatrogenic venous compression (IAVC) and related deep venous thrombosis (DVT) is under-recognized and under-reported. In the absence of relieving the compressive pathology, the recanalization rates are expected to be very low - thereby putting patients at a significant risk for the development of post-thrombotic syndrome (PTS). In this report, we describe two cases of DVT related to IAVC, and review similar cases that have been previously reported in the literature. With advancements in catheter-based technology, patients with IAVC (with or without DVT) may now be offered advanced endovascular treatment options such as catheter-directed pharmacomechanical thrombolysis (PMT) and percutaneous venoplasty and/or stenting. Hence, timely recognition and treatment is essential in the prevention of disabling PTS or life-threatening pulmonary embolism.
authors.affiliation: Temple University Hospital, Department of Medicine, Section of Cardiovascular Diseases, Philadelphia, PA, USA.
authors.forename: Moses
authors.initials: M
authors.lastname: Mathur
authors.affiliation: Temple University Hospital, Department of Medicine, Section of Cardiovascular Diseases, Philadelphia, PA, USA.
authors.forename: Irfan
authors.initials: I
authors.lastname: Shafi
authors.affiliation: Temple University Hospital, Department of Medicine, Section of Cardiovascular Diseases, Philadelphia, PA, USA.
authors.forename: Mohamad
authors.initials: M
authors.lastname: Alkhouli
authors.affiliation: Temple University Hospital, Department of Medicine, Section of Cardiovascular Diseases, Philadelphia, PA, USA riyaz.bashir@tuhs.temple.edu.
authors.forename: Riyaz
authors.initials: R
authors.lastname: Bashir
mesh_terms: D000293:Adolescent; D005260:Female; D005268:Femoral Vein / Q000601:surgery*; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D007049:Iatrogenic Disease / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D054070:Postthrombotic Syndrome / Q000175:diagnosis / Q000628:therapy*; D015912:Thrombolytic Therapy; D020246:Venous Thrombosis / Q000175:diagnosis / Q000628:therapy*
chemical_list: D005343:Fibrinolytic Agents
keywords: catheter-directed thrombolysis; deep vein thrombosis; iatrogenic; percutaneous intervention; venous compression