title: A shared architecture for promoters and enhancers.
abstract: A new study detects unstable nascent RNAs and uncovers thousands of transcription initiation sites in promoters and enhancers. Detailed analysis shows that these initiation sites have a similar architecture and that they are differentiated by post-transcriptional regulation rather than transcription initiation.
authors.affiliation: Department of Computer Science and Applied Mathematics and the Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
authors.forename: Shira
authors.initials: S
authors.lastname: Weingarten-Gabbay
authors.affiliation: Department of Computer Science and Applied Mathematics and the Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
authors.forename: Eran
authors.initials: E
authors.lastname: Segal
mesh_terms: D004742:Enhancer Elements, Genetic; D006801:Humans; D011401:Promoter Regions, Genetic; D012313:RNA / Q000235:genetics*
chemical_list: D012313:RNA