title: Recent progress in radiofrequency ablation therapy for hepatocellular carcinoma.
abstract: In order to attain better ablation and more effective management of hepatocellular carcinoma (HCC), new approaches and devices in radiofrequency ablation (RFA) therapy were presented and discussed in a workshop at the 50th Annual Meeting of the Liver Cancer Study Group of Japan. A novel bipolar RFA apparatus was introduced in Japan in January 2013. Hundreds of subjects with HCC were treated with multipolar RFA with varied devices and plans. Among these, no-touch ablation was one of the most useful procedures in the treatment of HCC with the apparatus. In RFA therapy, a few assisting devices and techniques were applied for convenience and improvement of the thermal ablation procedure. Contrast-enhanced ultrasonography and three-dimensional fusion imaging technique using volume data of CT or MRI could improve exact targeting and shorten the treatment time for RFA procedures under ultrasonographic guidance. A more complicated method using a workstation was also reported as being helpful in planning the ablated shape and volume in multineedle RFA. The effective use of sedatives and antianalgesics as well as a novel microwave apparatus with a cooled-tip electrode was also discussed.
authors.affiliation: Department of Hepatology, Toranomon Hospital and Okinaka Memorial Institution of Medical Research, Tokyo, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Ikeda
authors.forename: Yukio
authors.initials: Y
authors.lastname: Osaki
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakanishi
authors.forename: Akihiro
authors.initials: A
authors.lastname: Nasu
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Kawamura
authors.forename: Koji
authors.initials: K
authors.lastname: Jyoko
authors.forename: Takatomo
authors.initials: T
authors.lastname: Sano
authors.forename: Hajime
authors.initials: H
authors.lastname: Sunagozaka
authors.forename: Koji
authors.initials: K
authors.lastname: Uchino
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Minami
authors.forename: Yu
authors.initials: Y
authors.lastname: Saito
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Nagai
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Inokuchi
authors.forename: Shigehiro
authors.initials: S
authors.lastname: Kokubu
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Kudo
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000628:therapy*; D017115:Catheter Ablation / Q000295:instrumentation / Q000379:methods* / Q000639:trends*; D003287:Contrast Media; D005290:Ferric Compounds; D006801:Humans; D007501:Iron; D007564:Japan; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D008872:Microwaves; D010087:Oxides; D013696:Temperature; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional / Q000379:methods
chemical_list: D003287:Contrast Media; D005290:Ferric Compounds; D010087:Oxides; C069727:Sonazoid; D007501:Iron