title: Effects of chronic exercise on severity, quality of life and functionality in an elderly Parkinson's disease patient: case report.
abstract: Exercise produces potential influences on physical and mental capacity in patients with neuropsychiatric disorders, and can be made a viable form of therapy to treat Parkinson's disease (PD). We report the chronic effects of a regular physical exercise protocol on cognitive and motor functions, functional capacity, and symptoms in an elderly PD patient without dementia. The patient participated of a program composed of proprioceptive, aerobic and flexibility exercises, during 1 hour, three days a week, for nine months. Patient used 600 mg of L-DOPA daily, and 1 hour prior to each exercise session. Assessment was conducted in three stages, 0-3, 3-6 and 6 to 9 months, using percentual variation to the scales Hoehn and Yahr, Mini-Mental State Examination (MMSE), Parkinson Activity Scale (PAS), Beck Depression Inventory (BDI), and Unified Parkinson's Disease Rating Scale (UPDRS-III). Reassessment showed clear changes in clinical parameters for Hoehn and Yahr (4 to 2.5), MMSE (14 to 22), PAS (13 to 29), BDI (9 to 7) and UPDRS-III (39 to 27) at the end of 9 months. According to our data, exercise seems to be effective in promoting the functional capacity and the maintenance of cognitive and motor functions of PD patients. Regular exercise protocols can be implemented as an adjunctive treatment for reducing the severity of PD.
authors.affiliation: Panic & Respiration Laboratory, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil; National Institute for Translational Medicine (INCT-TM), Brazil.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Lattari
authors.affiliation: Physical Activity Neuroscience, Physical Activity Postgraduate Program, Salgado de Oliveira University (UNIVERSO), Niterói - RJ, Brazil;
authors.forename: Pedro Paulo
authors.initials: PP
authors.lastname: Pereira-Junior
authors.affiliation: Physical Activity Neuroscience, Physical Activity Postgraduate Program, Salgado de Oliveira University (UNIVERSO), Niterói - RJ, Brazil;
authors.forename: Geraldo Albuquerque Maranhão
authors.initials: GA
authors.lastname: Neto
authors.affiliation: Panic & Respiration Laboratory, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil; National Institute for Translational Medicine (INCT-TM), Brazil.
authors.forename: Murilo Khede
authors.initials: MK
authors.lastname: Lamego
authors.affiliation: Panic & Respiration Laboratory, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil; National Institute for Translational Medicine (INCT-TM), Brazil.
authors.forename: Antonio Marcos de Souza
authors.initials: AM
authors.lastname: Moura
authors.affiliation: Panic & Respiration Laboratory, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil; National Institute for Translational Medicine (INCT-TM), Brazil.
authors.forename: Alberto Souza
authors.initials: AS
authors.lastname: de Sá
authors.affiliation: Panic & Respiration Laboratory, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil; National Institute for Translational Medicine (INCT-TM), Brazil.
authors.forename: Ridson Rosa
authors.initials: RR
authors.lastname: Rimes
authors.affiliation: Panic & Respiration Laboratory, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil; National Institute for Translational Medicine (INCT-TM), Brazil.
authors.forename: João Paulo
authors.initials: JP
authors.lastname: Manochio
authors.affiliation: Unidad de Trastornos de Movimiento y Sueño, Hospital General Dr. Manuel Gea Gonzalez, Secretaria de Salud México DF, México.
authors.forename: Oscar
authors.initials: O
authors.lastname: Arias-Carrión
authors.affiliation: Department of Public Health, Clinical and Molecular Medicine. University of Cagliari, Italy.
authors.forename: Gioia
authors.initials: G
authors.lastname: Mura
authors.affiliation: Panic & Respiration Laboratory, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil; National Institute for Translational Medicine (INCT-TM), Brazil.
authors.forename: Antonio E
authors.initials: AE
authors.lastname: Nardi
authors.affiliation: Panic & Respiration Laboratory, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil; National Institute for Translational Medicine (INCT-TM), Brazil ; Physical Activity Neuroscience, Physical Activity Postgraduate Program, Salgado de Oliveira University (UNIVERSO), Niterói - RJ, Brazil;
authors.forename: Sergio
authors.initials: S
authors.lastname: Machado
keywords: Exercise; Parkinson’s disease; functional capacity; severity.