title: Gastric intramucosal adenocarcinoma with an invasive micropapillary carcinoma component.
abstract: A 70-year-old woman was referred to our hospital because of early gastric cancer (lesser curvature of the antrum, 0-IIc, tub1, 15 mm) and underwent endoscopic submucosal dissection. Microscopically, the lesion was found to be confined to the mucosa, and predominantly composed of well-differentiated tubular adenocarcinoma with a micropapillary component. On immunohistochemical examination, the characteristic "inside-out pattern" of the micropapillary component was observed; thus, we diagnosed the lesion as gastric cancer with a micropapillary component. Invasive micropapillary carcinoma is a rare subtype of gastric carcinoma, and, to our knowledge, this is the first case of invasive micropapillary carcinoma of the stomach confined to the mucosa.
authors.affiliation: Department of Gastroenterology, Suzuka General Hospital, Yamanohana, Yasuzuka, Suzuka-Shi, Mie, 1275-53, Japan, hiroki.tanaka@miekosei.or.jp.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Tanaka
authors.forename: Youichirou
authors.initials: Y
authors.lastname: Baba
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Sase
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Isono
authors.forename: Shimpei
authors.initials: S
authors.lastname: Matsusaki
authors.forename: Tomonori
authors.initials: T
authors.lastname: Saito
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Okano
authors.forename: Katsumi
authors.initials: K
authors.lastname: Mukai
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Murata
authors.forename: Gen
authors.initials: G
authors.lastname: Watanabe
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000231:Adenocarcinoma, Papillary / Q000473:pathology* / Q000601:surgery; D000368:Aged; D004210:Dissection; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology* / Q000601:surgery; D005773:Gastroscopy; D006801:Humans; D009361:Neoplasm Invasiveness; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery