title: Effect of Water Content on Enthalpic Relaxations in Porcine Septal Cartilage.
abstract: Cartilage thermoforming is an emerging surgical technology which uses heat to accelerate stress relaxation in mechanically deformed tissue specimens. Heat induced shape change in cartilage is associated with complex thermo mechanical behavior of which the mechanisms are still a subject of debate. Differential scanning calorimetry (DSC) was used to characterize the threshold temperatures and enthalpies in cartilage as a function of water content. The DSC identified two enthalpic events in porcine nasal septal cartilage, which depend on the water content. The change in the water content of cartilage impacts the interactions between matrix macromolecules and water molecules, which may be associated with a bound-free water transformation (reversible process) and a denaturation of cartilage (irreversible process).
authors.affiliation: The Beckman Laser Institute, 1002 Health Sciences Rd., Irvine, CA 92612, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Chae
authors.affiliation: The Beckman Laser Institute, 1002 Health Sciences Rd., Irvine, CA 92612, USA.
authors.forename: D
authors.initials: D
authors.lastname: Protsenko
authors.affiliation: Department of Chemical Engineering and Materials Science, University of California, Davis, One Shields Avenue, Davis, CA 92697, USA.
authors.forename: E J
authors.initials: EJ
authors.lastname: Lavernia
authors.affiliation: The Beckman Laser Institute, Department of Otolaryngology- Head and Neck Surgery, Department of Biomedical Engineering, University of California, Irvine, Irvine, CA 92697, USA.
authors.forename: B J F
authors.initials: BJ
authors.lastname: Wong
keywords: TMDSC; cartilage; cartilage reshaping; enthalpic relaxation; nasal septum; thermal transition; threshold temperature