title: Platelet function testing in acute cardiac care - is there a role for prediction or prevention of stent thrombosis and bleeding?
abstract: The role of platelet function testing in acute coronary syndrome patients undergoing percutaneous coronary intervention remains controversial despite the fact that high platelet reactivity is an independent predictor of stent thrombosis and emerging evidence suggests also a link between low platelet reactivity and bleeding. In this expert opinion paper, the Study Group on Biomarkers in Cardiology of the Acute Cardiovascular Care Association and the Working Group on Thrombosis of the European Society of Cardiology aim to provide an overview of current evidence in this area and recommendations for practicing clinicians.
authors.affiliation: Daniel Aradi, MD, PhD, Heart and Vascular Center, Semmelweis University, Hungary, 2 Gyogy Sq. Balatonfüred, 8230 Hungary, Tel.: +36 302355639, E-mail: daniel_aradi@yahoo.com.
authors.forename: Dániel
authors.initials: D
authors.lastname: Aradi
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Collet
authors.forename: Johannes
authors.initials: J
authors.lastname: Mair
authors.forename: Mario
authors.initials: M
authors.lastname: Plebani
authors.forename: Béla
authors.initials: B
authors.lastname: Merkely
authors.forename: Allan S
authors.initials: AS
authors.lastname: Jaffe
authors.forename: Martin
authors.initials: M
authors.lastname: Möckel
authors.forename: Evangelos
authors.initials: E
authors.lastname: Giannitsis
authors.forename: Kristian
authors.initials: K
authors.lastname: Thygesen
authors.forename: Jurrien M
authors.initials: JM
authors.lastname: ten Berg
authors.forename: Christian
authors.initials: C
authors.lastname: Mueller
authors.forename: Robert F
authors.initials: RF
authors.lastname: Storey
authors.forename: Bertil
authors.initials: B
authors.lastname: Lindahl
authors.forename: Kurt
authors.initials: K
authors.lastname: Huber
mesh_terms: D054058:Acute Coronary Syndrome / Q000150:complications* / Q000628:therapy; D002309:Cardiology / Q000379:methods / Q000592:standards*; D005060:Europe; D006470:Hemorrhage / Q000175:diagnosis / Q000517:prevention & control*; D006801:Humans; D016017:Odds Ratio; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D010979:Platelet Function Tests / Q000379:methods*; D017410:Practice Guidelines as Topic; D011379:Prognosis; D015607:Stents / Q000009:adverse effects*; D013927:Thrombosis / Q000175:diagnosis / Q000517:prevention & control*
chemical_list: D010975:Platelet Aggregation Inhibitors
keywords: Antiplatelet agents; acute myocardial infarction; platelet pharmacology