title: [Influence of thyroxine on display of dexamethasone's effects on M-response's parameters of skeletal muscle of white rats].
abstract: In the studies on white rats-females it was studied the dynamics of the change of some parameters of the M-response of a forward tibial muscle in the process of dexamethasone injection (in a dose of 0.25 mg/kg), applied separately and combined with injection of thyroxine (in a dose of 10 mkg/kg). It was established that the application of thyroxine in a complex with dexamethasone prevented the lengthening of the latent period, the decrease of amplitude and the shortening of the duration of the M-responses, taking place at the isolated injection of dexamethasone and also caused an essential decrease of frequency of polyphase potentials of the muscle. Besides, thyroxine prevented the development of the essential decrement of the amplitude and the lengthening of the latent period of M-responses in the process of indirect electric stimulation of the muscle with a frequency of 4 imp/s, typical of the isolated application of dexamethasone.
authors.forename: V I
authors.initials: VI
authors.lastname: Sobolev
authors.forename: V V
authors.initials: VV
authors.lastname: Trush
mesh_terms: D000818:Animals; D003907:Dexamethasone / Q000008:administration & dosage*; D004338:Drug Combinations; D004558:Electric Stimulation; D005260:Female; D009119:Muscle Contraction / Q000187:drug effects; D018482:Muscle, Skeletal / Q000187:drug effects / Q000503:physiopathology; D051381:Rats; D013974:Thyroxine / Q000008:administration & dosage*
chemical_list: D004338:Drug Combinations; D003907:Dexamethasone; D013974:Thyroxine