title: A CRISPR design for next-generation antimicrobials.
abstract: Two recent publications have demonstrated how delivering CRISPR nucleases provides a promising solution to the growing problem of bacterial antibiotic resistance.
authors.forename: Chase L
authors.initials: CL
authors.lastname: Beisel
authors.forename: Ahmed A
authors.initials: AA
authors.lastname: Gomaa
authors.forename: Rodolphe
authors.initials: R
authors.lastname: Barrangou
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D064113:CRISPR-Cas Systems; D004352:Drug Resistance, Microbial / Q000235:genetics*; D054324:Enterohemorrhagic Escherichia coli / Q000235:genetics*; D018390:Gene Targeting; D000094704:RNA, Guide, CRISPR-Cas Systems / Q000235:genetics*; D012260:Ribonucleases / Q000235:genetics*
chemical_list: D000890:Anti-Infective Agents; D000094704:RNA, Guide, CRISPR-Cas Systems; D012260:Ribonucleases