title: Label-free detection of Alzheimer's disease through the ADP3 peptoid recognizing the serum amyloid-beta42 peptide.
abstract: The early diagnosis of Alzheimer's disease (AD) is challenging due to the lack of reliable methods for detecting its biomarkers in the noninvasive biopsies. We used surface plasmon resonance imaging to identify AD based on the detection of amyloid-beta42 in the serum by the ADP3 peptoid.
authors.affiliation: National Center for Nanoscience and Technology, No. 11, Beiyitiao Zhongguancun, Beijing, 100190, P.R. China. zhul@nanoctr.cn huzy@nanoctr.cn.
authors.forename: Zijian
authors.initials: Z
authors.lastname: Zhao
authors.forename: Ling
authors.initials: L
authors.lastname: Zhu
authors.forename: Xiangli
authors.initials: X
authors.lastname: Bu
authors.forename: Huailei
authors.initials: H
authors.lastname: Ma
authors.forename: Shu
authors.initials: S
authors.lastname: Yang
authors.forename: Yanlian
authors.initials: Y
authors.lastname: Yang
authors.forename: Zhiyuan
authors.initials: Z
authors.lastname: Hu
mesh_terms: D000544:Alzheimer Disease / Q000097:blood* / Q000175:diagnosis; D016229:Amyloid beta-Peptides / Q000097:blood*; D004867:Equipment Design; D006801:Humans; D010446:Peptide Fragments / Q000097:blood*; D034444:Peptoids / Q000737:chemistry*; D020349:Surface Plasmon Resonance / Q000295:instrumentation*
chemical_list: D016229:Amyloid beta-Peptides; D010446:Peptide Fragments; D034444:Peptoids; C075222:amyloid beta-protein (1-42)