title: Phototherapy with combination of super-pulsed laser and light-emitting diodes is beneficial in improvement of muscular performance (strength and muscular endurance), dyspnea, and fatigue sensation in patients with chronic obstructive pulmonary disease.
abstract: Phototherapy is an electrophysical intervention being considered for the retardation of peripheral muscular fatigue usually observed in chronic obstructive pulmonary disease (COPD). The objective of this study was to evaluate the acute effects of combination of super-pulsed laser and light-emitting diodes phototherapy on isokinetic performance in patients with COPD. Thirteen patients performed muscular endurance tests in an isokinetic dynamometer. The maximum voluntary isometric contraction (MVIC), peak torque (PT), and total work (TW) of the non-dominant lower limb were measured in two visits. The application of phototherapy or placebo (PL) was conducted randomly in six locations of femoral quadriceps muscle by using a cluster of 12 diodes (4 of 905 nm super-pulsed lasers, 0.3125 mW each; 4 of 875 nm LEDs, 17.5 mW each; and 4 of 640 nm LEDs, 15 mW each, manufactured by Multi Radiance Medical™). We found statistically significant increases for PT (174.7 ± 35.7 N · m vs. 155.8 ± 23.3 N · m, p = 0.003) and TW after application of phototherapy when compared to placebo (778.0 ± 221.1 J vs. 696.3 ± 146.8 J, p = 0.005). Significant differences were also found for MVIC (104.8 ± 26.0 N · m vs. 87.2 ± 24.0 N · m, p = 0.000), sensation of dyspnea (1 [0-4] vs. 3 [0-6], p = 0.003), and fatigue in the lower limbs (2 [0-5] vs. 5 [0.5-9], p = 0.002) in favor of phototherapy. We conclude that the combination of super-pulsed lasers and LEDs administered to the femoral quadriceps muscle of patients with COPD increased the PT by 20.2% and the TW by 12%. Phototherapy with a combination of super-pulsed lasers and LEDs prior to exercise also led to decreased sensation of dyspnea and fatigue in the lower limbs in patients with COPD.
authors.affiliation: Post-Graduate Program in Biophotonics Applied to Health Sciences, Nove de Julho University, Rua Vergueiro, 235, 01504-001, São Paulo, SP, Brazil.
authors.forename: Eduardo Foschini
authors.initials: EF
authors.lastname: Miranda
authors.forename: Luís Vicente Franco
authors.initials: LV
authors.lastname: de Oliveira
authors.forename: Fernanda Colella
authors.initials: FC
authors.lastname: Antonialli
authors.forename: Adriane Aver
authors.initials: AA
authors.lastname: Vanin
authors.forename: Paulo de Tarso Camillo
authors.initials: Pde T
authors.lastname: de Carvalho
authors.forename: Ernesto Cesar Pinto
authors.initials: EC
authors.lastname: Leal-Junior
mesh_terms: D004417:Dyspnea / Q000150:complications*; D006801:Humans; D007834:Lasers; D008875:Middle Aged; D018763:Muscle Fatigue / Q000528:radiation effects*; D053580:Muscle Strength / Q000528:radiation effects*; D009132:Muscles / Q000503:physiopathology / Q000528:radiation effects*; D055095:Optics and Photonics; D010789:Phototherapy; D010807:Physical Endurance / Q000528:radiation effects; D010919:Placebos; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology*; D012677:Sensation; D019415:Torque
chemical_list: D010919:Placebos