title: SIOP PODC adapted treatment recommendations for standard-risk medulloblastoma in low and middle income settings.
abstract: Effective treatment of children with medulloblastoma requires a functioning multi-disciplinary team with adequate neurosurgical, neuroradiological, pathological, radiotherapy and chemotherapy facilities and personnel. In addition the treating centre should have the capacity to effectively screen and manage any tumour and treatment-associated complications. These requirements have made it difficult for many low and middle-income countries (LMIC) centres to offer curative treatment. This article provides management recommendations for children with standard-risk medulloblastoma (localised tumours in children over the age of 3-5 years) according to the level of facilities available.
authors.affiliation: Department of Radiation Oncology, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa.
authors.forename: Jeannette
authors.initials: J
authors.lastname: Parkes
authors.forename: Marc
authors.initials: M
authors.lastname: Hendricks
authors.forename: Peter
authors.initials: P
authors.lastname: Ssenyonga
authors.forename: John
authors.initials: J
authors.lastname: Mugamba
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Molyneux
authors.forename: Antoinette
authors.initials: A
authors.lastname: Schouten-van Meeteren
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Qaddoumi
authors.forename: Graham
authors.initials: G
authors.lastname: Fieggen
authors.forename: Sandra
authors.initials: S
authors.lastname: Luna-Fineman
authors.forename: Scott
authors.initials: S
authors.lastname: Howard
authors.forename: Dipayan
authors.initials: D
authors.lastname: Mitra
authors.forename: Eric
authors.initials: E
authors.lastname: Bouffet
authors.forename: Alan
authors.initials: A
authors.lastname: Davidson
authors.forename: Simon
authors.initials: S
authors.lastname: Bailey
mesh_terms: D002173:Cancer Care Facilities / Q000191:economics / Q000592:standards; D002528:Cerebellar Neoplasms / Q000175:diagnosis* / Q000191:economics / Q000628:therapy*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007182:Income; D008297:Male; D008527:Medulloblastoma / Q000175:diagnosis* / Q000191:economics / Q000628:therapy*; D012307:Risk Factors
keywords: brain; chemotherapy; pediatric hematology/oncology; tumours