title: Simultaneous determination of six constituents in Mahuang Fuzi Xixin by UPLC-PDA-MS/MS.
abstract: Mahuang Fuzi Xixin (MFX), a classic recipe in traditional Chinese medicine, belongs to an exterior-relieving formula. For quality control of the MFX products, qualitative analysis using ultra-high performance liquid chromatography with diode-array detector-tandem mass spectrometry (UPLC-PDA-MS/MS) was undertaken. Six compounds from the MFX were simultaneously detected. Among them, astragalin and kaempferol 3-rutinoside were quantified through the UPLC-MS/MS method, while asarinin, sesamin, kakuol and methyleugenol were quantified through the UPLC-PDA method. This method can be applied to the quantitative determination of the six compounds in the MFX.
authors.affiliation: a School of Pharmacy, Shenyang Pharmaceutical University , 110016 Shenyang , P.R. China.
authors.forename: Lin
authors.initials: L
authors.lastname: Zhang
authors.forename: Chengying
authors.initials: C
authors.lastname: Wang
authors.forename: Dezu
authors.initials: D
authors.lastname: Miao
authors.forename: Dan
authors.initials: D
authors.lastname: Yuan
authors.forename: Kaishun
authors.initials: K
authors.lastname: Bi
authors.forename: Jingyu
authors.initials: J
authors.lastname: Yang
authors.forename: Libin
authors.initials: L
authors.lastname: Zhan
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004224:Diterpenes; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D029790:Ephedra sinica / Q000737:chemistry*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*; D053719:Tandem Mass Spectrometry
chemical_list: D004224:Diterpenes; D004365:Drugs, Chinese Herbal; D010936:Plant Extracts; C575009:fuzi drug herbal
keywords: Mahuang Fuzi Xixin; UPLC-PDA–MS/MS; simultaneous determination