title: Measurement of regional forearm muscle haemodynamics via the near-infrared spectroscopy venous occlusion technique: the impact of hand circulatory occlusion.
abstract: The purpose of this study was to examine whether circulatory occlusion of the hand impacts on regional forearm muscle haemodynamics as determined by the near-infrared spectroscopy (NIRS) venous occlusion technique (NIRSVOT). Twenty-five young, healthy participants (18 males and 7 females; 28 ± 4 years; 71 ± 7 kg) completed two experimental protocols that were performed on the dominant arm: (1) a series of five venous occlusion trials with a suprasystolic cuff (>260 mmHg) applied to the wrist and (2) five venous occlusion trials without hand-occlusion. Both protocols were performed twice in a counterbalanced manner. NIRS data were obtained from the flexor digitorum superficialis (FDS) muscle using a dual wavelength, continuous-wave spectrophotometer. FDS muscle blood flow (Q(FDS)), vascular conductance (C(FDS)), O2 consumption (Vo(2FDS)), and venous O2 saturation (SvO2) were calculated from NIRS data during the initial 5 s of venous occlusion. Circulatory occlusion of the hand via wrist cuffing significantly (P < 0.05) reduced Q(FDS) (-36 ± 23%), CFDS (-37 ± 23%), Vo2(FDS) (-14 ± 31%) and SvO2 (-14 ± 12%). These findings indicate that hand-occlusion, via wrist cuffing, adversely impacts on regional forearm haemodynamics as determined by the NIRS-VOT. Consequently, it is recommended that future investigators avoid hand-occlusion when using the NIRS-VOT to quantify spontaneous haemodynamics of regional forearm muscle.
authors.forename: T J
authors.initials: TJ
authors.lastname: Cross
authors.forename: M
authors.initials: M
authors.lastname: van Beekvelt
authors.forename: K
authors.initials: K
authors.lastname: Constantini
authors.forename: S
authors.initials: S
authors.lastname: Sabapathy
mesh_terms: D000328:Adult; D005260:Female; D005542:Forearm; D006225:Hand / Q000098:blood supply*; D006439:Hemodynamics; D006801:Humans; D008297:Male; D018482:Muscle, Skeletal / Q000378:metabolism / Q000502:physiology*; D010101:Oxygen Consumption; D012039:Regional Blood Flow; D019265:Spectroscopy, Near-Infrared; D014680:Veins / Q000502:physiology*