title: Supported lipid bilayers as dynamic platforms for tethered particles.
abstract: Nanoparticle tethering to lipid bilayers enables the observation of hundreds of diffusing particles that are confined within a single field of view. A wide variety of materials ranging from plasmonic metals to soft matter can be stably tethered to the surface of a fluid bilayer by covalent or non-covalent means. The controlled environment of this experimental platform allows direct control over surface compositions and accurate tracking of nanoparticle interactions. This minireview will cover studies that use bilayer-tethered nanoparticles to investigate physical properties related to lipid mobility, biomolecule sensing, and surface interactions, as well as experiments to reversibly manipulate tethered nanoparticles by electric fields.
authors.affiliation: Department of Chemistry, Seoul National University, Gwanak-gu, Seoul, 151-747, South Korea. jmnam@snu.ac.kr.
authors.forename: Kevin L
authors.initials: KL
authors.lastname: Hartman
authors.forename: Sungi
authors.initials: S
authors.lastname: Kim
authors.forename: Keunsuk
authors.initials: K
authors.lastname: Kim
authors.forename: Jwa-Min
authors.initials: JM
authors.lastname: Nam
mesh_terms: D000327:Adsorption; D001704:Biopolymers / Q000737:chemistry*; D008051:Lipid Bilayers / Q000737:chemistry*; D008560:Membrane Fluidity; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure*
chemical_list: D001704:Biopolymers; D008051:Lipid Bilayers