title: Probable disseminated BCG infection in a 10-month-old child after BCG vaccination.
abstract: The disseminated BCG infection is a rare and serious complication of bacillus Calmette-Guerin (BCG) vaccine. We report a case of probable disseminated BCG infection in a 10-month-old child who had been vaccinated by BCG vaccine at birth. No incident was noted on the first days of vaccination. At the age of 40 days, she developed left supra clavicular and axillar abcessed lymph nodes. She was treated by surgical flattening of the lymph adenopathy. The same lymph node recurred at the age of 6 months and was treated with surgery. Few weeks after the second episode, cutaneous ulcerative lesions appeared. Cutaneous biopsy was performed and showed lesions compatible with tuberculosis. X-rays showed osteolysis of P1 of the middle finger in the left hand. She was treated by anti-tuberculosis antibiotics.
authors.affiliation: a National Center of Pharmacovigilance; Tunis, Tunisia.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Zaïem
authors.forename: Senda
authors.initials: S
authors.lastname: El Ferjani
authors.forename: Ghozlane
authors.initials: G
authors.lastname: Lakhoua
authors.forename: Rym
authors.initials: R
authors.lastname: Sahnoun
authors.forename: Talel
authors.initials: T
authors.lastname: Badri
authors.forename: Sarrah
authors.initials: S
authors.lastname: Kastalli
authors.forename: Riadh
authors.initials: R
authors.lastname: Daghfous
authors.forename: Mohamed
authors.initials: M
authors.lastname: Lakhal
authors.forename: Sihem
authors.initials: S
authors.lastname: El Aidli
mesh_terms: D001500:BCG Vaccine / Q000008:administration & dosage* / Q000009:adverse effects*; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D009163:Mycobacterium bovis / Q000302:isolation & purification*; D011859:Radiography; D012867:Skin / Q000473:pathology; D014376:Tuberculosis / Q000175:diagnosis* / Q000382:microbiology* / Q000473:pathology
chemical_list: D001500:BCG Vaccine
keywords: BCG vaccine; adverse effect following immunization; disseminated infection