title: Withanolides from three species of the genus Deprea (Solanaceae). Chemotaxonomical considerations.
abstract: Nine withanolides were isolated from the aerial parts of Deprea bitteriana, Depreacuyacensis, and Depreazamorae. D.bitteriana yielded two withaphysalins, D. cuyacensis gave two 13,14-seco withaphysalins, while D. zamorae yielded five physangulidines. The compounds were fully characterized by a combination of spectroscopic methods (1D and 2D NMR and MS). All compounds isolated from D.bitteriana and D. cuyacensis were obtained as epimeric mixtures at C-18. The structure of physangulidine D was confirmed by X-ray diffraction analysis. The skeletons found in this research support the chemotaxonomical position of the genus Deprea in the tribe Physalideae.
authors.affiliation: Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Instituto Multidisciplinario de Biología Vegetal (IMBIV-CONICET), Casilla de Correo 495, 5000 Córdoba, Argentina.
authors.forename: Carina N
authors.initials: CN
authors.lastname: Casero
authors.affiliation: Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Instituto Multidisciplinario de Biología Vegetal (IMBIV-CONICET), Casilla de Correo 495, 5000 Córdoba, Argentina.
authors.forename: Juan C
authors.initials: JC
authors.lastname: Oberti
authors.affiliation: Instituto de Ciencias Naturales, Universidad Nacional de Colombia, Apartado 7495, Bogotá, D.C., Colombia.
authors.forename: Clara I
authors.initials: CI
authors.lastname: Orozco
authors.affiliation: Instituto Universitario de Bio-Orgánica "Antonio González" IUBO-AG, Universidad de La Laguna, Avda. Astrofísico Francisco Sánchez 2, 38206 La Laguna, Spain.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Cárdenas
authors.affiliation: Instituto Universitario de Bio-Orgánica "Antonio González" IUBO-AG, Universidad de La Laguna, Avda. Astrofísico Francisco Sánchez 2, 38206 La Laguna, Spain.
authors.forename: Iván
authors.initials: I
authors.lastname: Brito
authors.affiliation: Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Instituto Multidisciplinario de Biología Vegetal (IMBIV-CONICET), Casilla de Correo 495, 5000 Córdoba, Argentina.
authors.forename: Gloria E
authors.initials: GE
authors.lastname: Barboza
authors.affiliation: Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Instituto Multidisciplinario de Biología Vegetal (IMBIV-CONICET), Casilla de Correo 495, 5000 Córdoba, Argentina. Electronic address: vnicotra@fcq.unc.edu.ar.
authors.forename: Viviana E
authors.initials: VE
authors.lastname: Nicotra
mesh_terms: D003105:Colombia; D018360:Crystallography, X-Ray; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D035261:Plant Components, Aerial / Q000737:chemistry; D019657:Solanaceae / Q000737:chemistry* / Q000145:classification / Q000235:genetics; D054358:Withanolides / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D054358:Withanolides
keywords: Chemotaxonomic markers; Deprea; Solanaceae; Withanolides