title: Occipital nerve stimulation.
abstract: Occipital nerve stimulation (ONS) is a form of neuromodulation therapy aimed at treating intractable headache and craniofacial pain. The therapy utilizes neurostimulating electrodes placed subcutaneously in the occipital region and connected to a permanently implanted programmable pulse generator identical to those used for dorsal column/spinal cord stimulation. The presumed mechanisms of action involve modulation of the trigeminocervical complex, as well as closure of the physiologic pain gate. ONS is a reversible, nondestructive therapy, which can be tailored to a patient's individual needs. Typically, candidates for successful ONS include those patients with migraines, Chiari malformation, or occipital neuralgia. However, recent MRSA infections, unrealistic expectations, and psychiatric comorbidities are generally contraindications. As with any invasive procedure, complications may occur including lead migration, infection, wound erosion, device failure, muscle spasms, and pain. The success of this therapy is dependent on careful patient selection, a preimplantation trial, meticulous implantation technique, programming strategies, and complication avoidance.
authors.affiliation: Department of Neurological Surgery, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA.
authors.forename: Antonios
authors.initials: A
authors.lastname: Mammis
authors.forename: Nitin
authors.initials: N
authors.lastname: Agarwal
authors.forename: Alon Y
authors.initials: AY
authors.lastname: Mogilner
mesh_terms: D004599:Electric Stimulation Therapy; D006261:Headache / Q000628:therapy*; D006801:Humans; D010146:Pain / Q000601:surgery*; D010147:Pain Measurement / Q000379:methods; D010525:Peripheral Nerves / Q000503:physiopathology*; D013127:Spinal Nerves / Q000503:physiopathology*