title: Bioelectronic light-gated transistors with biologically tunable performance.
abstract: Light-activated bioelectronic silicon nanowire transistor devices are made by fusing proteoliposomes containing a bacteriorhodopsin (bR) proton pump onto the nanowire surface. Under green-light illumination, bR pumps protons toward the nanowire, and the pH gradient developed by the pump changes the transistor output. Furthermore, co-assembly of small biomolecules that alter the bilayer permeability to other ions can upregulate and downregulate the response of field-effect transistor devices.
authors.affiliation: Biology and Biotechnology Division, Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California, 94550, USA; Materials Science and Chemical Engineering Department, University of California Davis, Davis, California, 95616, USA; The Molecular Foundry, Materials Sciences Division and.
authors.forename: Ramya H
authors.initials: RH
authors.lastname: Tunuguntla
authors.forename: Mangesh A
authors.initials: MA
authors.lastname: Bangar
authors.forename: Kyunghoon
authors.initials: K
authors.lastname: Kim
authors.forename: Pieter
authors.initials: P
authors.lastname: Stroeve
authors.forename: Costas
authors.initials: C
authors.lastname: Grigoropoulos
authors.forename: Caroline M
authors.initials: CM
authors.lastname: Ajo-Franklin
authors.forename: Aleksandr
authors.initials: A
authors.lastname: Noy
mesh_terms: D007700:Kinetics; D008027:Light; D008051:Lipid Bilayers / Q000737:chemistry* / Q000378:metabolism*; D008565:Membrane Proteins / Q000378:metabolism*; D008958:Models, Molecular; D008968:Molecular Conformation; D053770:Nanowires / Q000737:chemistry; D011522:Protons; D012825:Silicon / Q000737:chemistry; D014173:Transistors, Electronic
chemical_list: D008051:Lipid Bilayers; D008565:Membrane Proteins; D011522:Protons; D012825:Silicon
keywords: bacteriorhodopsin; bioelectronics; biological regulation; ionophores; silicon nanowire field-effect transistors (FETs)