title: Dengue fever: a Wikipedia clinical review.
abstract: Dengue fever, also known as breakbone fever, is a mosquito-borne infectious tropical disease caused by the dengue virus. Symptoms include fever, headache, muscle and joint pains, and a characteristic skin rash that is similar to measles. In a small proportion of cases, the disease develops into life-threatening dengue hemorrhagic fever, which results in bleeding, thrombocytopenia, and leakage of blood plasma, or into dengue shock syndrome, in which dangerously low blood pressure occurs. Treatment of acute dengue fever is supportive, with either oral or intravenous rehydration for mild or moderate disease and use of intravenous fluids and blood transfusion for more severe cases. Along with attempts to eliminate the mosquito vector, work is ongoing to develop a vaccine and medications targeted directly at the virus.
authors.affiliation: James M. Heilman, MD, CCFP(EM), is the Emergency Department Head at the East Kootenay Regional Hospital, Cranbrook, British Columbia, and is also a Clinical Instructor in the Department of Emergency Medicine, The University of British Columbia, Vancouver, British Columbia.
authors.forename: James M
authors.initials: JM
authors.lastname: Heilman
authors.affiliation: Jacob De Wolff, MRCP(UK), is a Consultant in Acute Medicine and High Dependency Medicine at Northwick Park Hospital, Harrow, Middlesex, UK.
authors.forename: Jacob
authors.initials: J
authors.lastname: De Wolff
authors.affiliation: Graham M. Beards, DSc, FIBMS, is a Clinical and Biomedical Scientist in blood science at Walsall Manor Hospital, Walsall, UK.
authors.forename: Graham M
authors.initials: GM
authors.lastname: Beards
authors.affiliation: Brian J. Basden, BSc, is a Researcher with Battelle Memorial Institute, Atlanta, Georgia.
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Basden
mesh_terms: D000818:Animals; D003715:Dengue / Q000503:physiopathology* / Q000517:prevention & control / Q000628:therapy; D053059:Dengue Vaccines; D005440:Fluid Therapy; D006801:Humans; D007303:Insect Vectors; D009032:Mosquito Control
chemical_list: D053059:Dengue Vaccines