title: [Complex pathogenetic treatment schemes of vascular dyscirculatory disorders in the remote period after exposure to low dose radiation].
abstract: Complex studies including modern methods of investigation of structures and functions of nervous system: electroencephalograsphy (EEG), coherent analysis, neuropsychological study and methods of neuroimaging were performed in 517 participants in liquidation of consequences of the accident (LCA) at the Chernobyl NPP in 1986-1987. Dyscirculatory metabolic encephalopathy was revealed to be the main pathology with the etiological mechanism based on dyscirculatorhypoxic and metabolic disorders. Complexity of the revealed symptoms testified to an early organism aging in remote periods after exposure to low dose radiation. Pathogenetic schemes were developed for treatment of dyscirculatory encephalopathy in liquidators, which include drugs improving blood supply, antiaggregants, antioxidants and metabolites of the brains in various combinations. Taking into consideration that early appearance of vascular dyscirculatory disorders observed in liquidators is the sign of early aging of the organism, geroprotectors were added to treatment schemes.
authors.forename: N B
authors.initials: NB
authors.lastname: Holodova
authors.forename: L A
authors.initials: LA
authors.lastname: Zhavoronkova
authors.forename: B N
authors.initials: BN
authors.lastname: Ryzhov
mesh_terms: D001921:Brain / Q000187:drug effects / Q000473:pathology / Q000528:radiation effects; D002561:Cerebrovascular Disorders / Q000188:drug therapy* / Q000473:pathology; D047852:Chernobyl Nuclear Accident; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D011829:Radiation Dosage; D011832:Radiation Injuries / Q000188:drug therapy* / Q000473:pathology