title: Synthesis of (phosphonomethyl)phosphinate pyrophosphate analogues via the phospha-Claisen condensation.
abstract: Pyrophosphate analogues are of great importance especially for the design of biologically active molecules. The phospha-Claisen condensation allows for the rapid synthesis of (phosphonomethyl)phosphinate pyrophosphate analogues and building blocks that can be employed in numerous applications.
authors.affiliation: Department of Chemistry, Box 298860, Texas Christian University, Fort Worth, Texas 76133, USA. j.montchamp@tcu.edu.
authors.forename: Fabien
authors.initials: F
authors.lastname: Gelat
authors.forename: Claire
authors.initials: C
authors.lastname: Lacomme
authors.forename: Olivier
authors.initials: O
authors.lastname: Berger
authors.forename: Laurent
authors.initials: L
authors.lastname: Gavara
authors.forename: J-L
authors.initials: JL
authors.lastname: Montchamp
mesh_terms: D050071:Bone Density Conservation Agents / Q000138:chemical synthesis*; D011756:Diphosphates / Q000138:chemical synthesis*; D004164:Diphosphonates / Q000138:chemical synthesis*; D015394:Molecular Structure; D010721:Phosphinic Acids / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D050071:Bone Density Conservation Agents; D011756:Diphosphates; D004164:Diphosphonates; D010721:Phosphinic Acids