title: One-step generation of p53 gene biallelic mutant Cynomolgus monkey via the CRISPR/Cas system.
authors.affiliation: State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
authors.forename: Haifeng
authors.initials: H
authors.lastname: Wan
authors.affiliation: 1] State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China [2] University of Chinese Academy of Sciences, Beijing 100049, China.
authors.forename: Chunjing
authors.initials: C
authors.lastname: Feng
authors.affiliation: 1] State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China [2] University of Chinese Academy of Sciences, Beijing 100049, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Teng
authors.affiliation: 1] College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong 510642, China [2] Key Laboratory of Comprehensive Prevention and Control for Severe Clinical Animal Diseases of Guangdong Province, Guangzhou, Guangdong 510642, China.
authors.forename: Shihua
authors.initials: S
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
authors.forename: Baoyang
authors.initials: B
authors.lastname: Hu
authors.affiliation: Yunnan Key Laboratory of Primate Biomedical Research, Kunming, Yunnan 650500, China.
authors.forename: Yuyu
authors.initials: Y
authors.lastname: Niu
authors.affiliation: Center for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Sun Yat-Sen University, Guangzhou, Guangdong 510080, China.
authors.forename: Andy Peng
authors.initials: AP
authors.lastname: Xiang
authors.affiliation: Beijing Xieerxin Institute of Biological Resources, Beijing, China.
authors.forename: Weizhen
authors.initials: W
authors.lastname: Fang
authors.affiliation: Yunnan Key Laboratory of Primate Biomedical Research, Kunming, Yunnan 650500, China.
authors.forename: Weizhi
authors.initials: W
authors.lastname: Ji
authors.affiliation: State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.affiliation: State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
authors.forename: Xiaoyang
authors.initials: X
authors.lastname: Zhao
authors.affiliation: State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhou
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D001483:Base Sequence; D064112:Clustered Regularly Interspaced Short Palindromic Repeats / Q000235:genetics*; D004622:Embryo, Mammalian / Q000378:metabolism; D008252:Macaca fascicularis / Q000235:genetics*; D016296:Mutagenesis; D012313:RNA / Q000378:metabolism; D016159:Tumor Suppressor Protein p53 / Q000235:genetics* / Q000378:metabolism
chemical_list: D016159:Tumor Suppressor Protein p53; D012313:RNA