title: Serous detachment of the macula associated with advanced glaucomatous cupping.
abstract: Enhanced depth imaging of the optic nerve of a patient with a serous detachment and profound cupping of the optic nerve secondary to angle-closure glaucoma revealed a large dehiscence of the lamina cribrosa. Adjacent to the defect in the lamina were cystoid spaces within the nerve appearing to contain fluid. The most temporal of these could be seen to extend through the optic nerve and up into the macula. This visualized pathway suggests that mechanical dehiscence of the lamina may allow fluid, possibly derived from cerebrospinal fluid, to track up into the macula.
authors.forename: Richard F
authors.initials: RF
authors.lastname: Spaide
mesh_terms: D005260:Female; D015812:Glaucoma, Angle-Closure / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007429:Intraocular Pressure; D008266:Macula Lutea; D008875:Middle Aged; D009898:Optic Disk / Q000473:pathology; D009901:Optic Nerve Diseases / Q000150:complications* / Q000175:diagnosis; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology*; D058471:Subretinal Fluid; D041623:Tomography, Optical Coherence; D014792:Visual Acuity