title: [Implementation of a telediagnostic system for tuberculosis and determination of multi-drug resistance based in the MODS method in Trujillo, Peru].
abstract: OBJECTIVE
  To implement a system for remote diagnosis of tuberculosis and multidrug resistance (MDR) using the Microscopic-Observation Drug Susceptibility Assay (MODS) method in the Mycobacteria Laboratory, Trujillo Center of Excellence in Tuberculosis (CENEX-Trujillo). The system included a variant of an algorithm for recognition of Mycobacterium tuberculosis recently reported from digital images of MODS cultures of sputum samples.
  
  
  METHODS
  The recognition algorithm was optimized using a retraining statistical model based on digital images of MODS cultures from CENEX-Trujillo. Images of 50 positive MODS cultures of patients with suspected multidrug-resistant tuberculosis were obtained between January and October 2012 in the CENEX-Trujillo.
  
  
  RESULTS
  The sensitivity and specificity to recognize strings of tuberculosis were 92.04% and 94.93% respectively using objects. The sensitivity and specificity to determine a positive tuberculosis field were 95.4% and 98.07% respectively using pictures.
  
  
  CONCLUSIONS
  The results demonstrated the feasibility of the implementation of telediagnostics in remote locations, which may contribute to the early detection of multidrug-resistant tuberculosis by MODS method.
authors.affiliation: Centro de Excelencia en Tuberculosis Luz Caviedes Rojas, Hospital Regional Docente de Trujillo, La Libertad, Perú
authors.forename: Luis
authors.initials: L
authors.lastname: Rodríguez
authors.affiliation: Laboratorio de Investigación en Enfermedades Infecciosas, Laboratorio de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Perú
authors.forename: Alicia
authors.initials: A
authors.lastname: Alva
authors.affiliation: Laboratorio de Investigación en Enfermedades Infecciosas, Laboratorio de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Perú
authors.forename: Jorge
authors.initials: J
authors.lastname: Coronel
authors.affiliation: Laboratorio de Investigación en Enfermedades Infecciosas, Laboratorio de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Perú
authors.forename: Luz
authors.initials: L
authors.lastname: Caviedes
authors.affiliation: Instituto Nacional de Salud, Lima, Perú
authors.forename: Alberto
authors.initials: A
authors.lastname: Mendoza-Ticona
authors.affiliation: ONG A.B. PRISMA, Lima, Perú
authors.forename: Robert
authors.initials: R
authors.lastname: Gilman
authors.affiliation: Laboratorio de Investigación en Enfermedades Infecciosas, Laboratorio de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Perú
authors.forename: Patricia
authors.initials: P
authors.lastname: Sheen
authors.affiliation: Laboratorio de Investigación en Enfermedades Infecciosas, Laboratorio de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Perú
authors.forename: Mirko
authors.initials: M
authors.lastname: Zimic
mesh_terms: D000465:Algorithms; D001431:Bacteriological Techniques; D003952:Diagnostic Imaging; D006801:Humans; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000254:growth & development; D010568:Peru; D017216:Telemedicine; D014376:Tuberculosis / Q000175:diagnosis*; D018088:Tuberculosis, Multidrug-Resistant / Q000175:diagnosis