title: Toward structural femtosecond chemical dynamics: imaging chemistry in space and time.
abstract: We aim to observe a chemical reaction in real time using gas-phase X-ray diffraction. In our initial experiment at the Linac Coherent Light Source (LCLS), we investigated the model system 1,3-cyclohexadiene (CHD) at very low vapor pressures. This reaction serves as a benchmark for numerous transformations in organic synthesis and natural product biology. Excitation of CHD by an ultraviolet optical pulse initiates an electrocyclic reaction that transforms the closed ring system into the open-chain structure of 1,3,5-hexatriene. We describe technical points of the experimental method and present first results. We also outline an approach to analyze the data involving nonlinear least-square optimization routines that match the experimental observations with predicted diffraction patterns calculated from trajectories for nonadiabatic vibronic wave packets.
authors.affiliation: SLAC National Accelerator Laboratory, Stanford, CA 94025, USA. minitti@slac.stanford.edu.
authors.forename: Michael P
authors.initials: MP
authors.lastname: Minitti
authors.forename: James M
authors.initials: JM
authors.lastname: Budarz
authors.forename: Adam
authors.initials: A
authors.lastname: Kirrander
authors.forename: Joseph
authors.initials: J
authors.lastname: Robinson
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Lane
authors.forename: Daniel
authors.initials: D
authors.lastname: Ratner
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Saita
authors.forename: Thomas
authors.initials: T
authors.lastname: Northey
authors.forename: Brian
authors.initials: B
authors.lastname: Stankus
authors.forename: Vale
authors.initials: V
authors.lastname: Cofer-Shabica
authors.forename: Jerome
authors.initials: J
authors.lastname: Hastings
authors.forename: Peter M
authors.initials: PM
authors.lastname: Weber
mesh_terms: D053138:Cyclohexenes / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D053138:Cyclohexenes; C034005:1,3-cyclohexadiene