title: IgG4-related sclerosing mesenteritis in a 7-year-old Saudi girl.
abstract: Sclerosing mesenteritis (SM) is a rare, benign inflammatory disorder of unknown etiology, affecting the membranes of the digestive tract that involves lymphoplasmacytic inflammation, fat necrosis, and fibrosis of the mesentery. We report a child patient with a history of recurrent abdominal pain and fever who was found to have an intra-abdominal mass suspicious for malignancy. A tissue biopsy revealed the diagnosis of SM associated with IgG4-related systemic disease. The patient is currently maintained on 5 mg prednisone daily and no recurrence of symptoms was noted during the 24-month follow-up period. We emphasize, therefore, that SM can present clinical challenges and the presence of SM should cue clinicians to search for other coexisting autoimmune disorders that can have various outcomes.
authors.affiliation: Department of Pediatric Gastroenterology, King Saud Bin Abdulaziz University for Health Sciences, National Guard Hospital, Jeddah, Saudi Arabia.
authors.forename: Mohammed Y
authors.initials: MY
authors.lastname: Hasosah
authors.forename: Mohamed B
authors.initials: MB
authors.lastname: Satti
authors.forename: Yasmin A
authors.initials: YA
authors.lastname: Yousef
authors.forename: Daifullah M
authors.initials: DM
authors.lastname: Alzahrani
authors.forename: Sajdi A
authors.initials: SA
authors.lastname: Almutairi
authors.forename: Ashraf F
authors.initials: AF
authors.lastname: Alsahafi
authors.forename: Ghassan A
authors.initials: GA
authors.lastname: Sukkar
authors.forename: Abdullah A
authors.initials: AA
authors.lastname: Alzaben
mesh_terms: D000888:Antibodies, Anti-Idiotypic / Q000097:blood / Q000276:immunology*; D001706:Biopsy; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood* / Q000276:immunology; D015436:Panniculitis, Peritoneal / Q000097:blood / Q000175:diagnosis / Q000276:immunology*; D012529:Saudi Arabia; D014057:Tomography, X-Ray Computed
chemical_list: D000888:Antibodies, Anti-Idiotypic; D007074:Immunoglobulin G