title: Reversible biomechano-responsive surface based on green fluorescent protein genetically modified with unnatural amino acids.
abstract: GFP has been genetically modified at two specific positions of its molecular architecture. These modifications allow its covalent attachment onto PEG brushes grafted on functionalized silicone surfaces. The stretching of this material leads to a reversible decrease of the fluorescence intensity due to stretch-induced forces applying on GFP molecules.
authors.affiliation: ICS (UPR22-CNRS), 23 rue du Loess, 67034, Strasbourg, France. schaaf@unistra.fr.
authors.forename: Johan
authors.initials: J
authors.lastname: Longo
authors.forename: Chunyan
authors.initials: C
authors.lastname: Yao
authors.forename: César
authors.initials: C
authors.lastname: Rios
authors.forename: Nguyet Trang Thanh
authors.initials: NT
authors.lastname: Chau
authors.forename: Fouzia
authors.initials: F
authors.lastname: Boulmedais
authors.forename: Joseph
authors.initials: J
authors.lastname: Hemmerlé
authors.forename: Philippe
authors.initials: P
authors.lastname: Lavalle
authors.forename: Stefan M
authors.initials: SM
authors.lastname: Schiller
authors.forename: Pierre
authors.initials: P
authors.lastname: Schaaf
authors.forename: Loïc
authors.initials: L
authors.lastname: Jierry
mesh_terms: D000596:Amino Acids / Q000737:chemistry / Q000378:metabolism*; D001593:Benzyl Compounds / Q000737:chemistry; D057930:Click Chemistry; D004129:Dimethylpolysiloxanes / Q000737:chemistry; D049452:Green Fluorescent Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D048288:Imidazolines / Q000737:chemistry; D008856:Microscopy, Fluorescence; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000737:chemistry / Q000235:genetics; D012825:Silicon / Q000737:chemistry
chemical_list: D000596:Amino Acids; D001593:Benzyl Compounds; D004129:Dimethylpolysiloxanes; D048288:Imidazolines; D011994:Recombinant Proteins; C529028:p-hydroxybenzylideneimidazolinone; D049452:Green Fluorescent Proteins; C013830:baysilon; D012825:Silicon