title: Time-varying correlations between delta EEG power and heart rate variability in midlife women: the SWAN Sleep Study.
abstract: No studies have evaluated the dynamic, time-varying relationship between delta electroencephalographic (EEG) sleep and high frequency heart rate variability (HF-HRV) in women. Delta EEG and HF-HRV were measured during sleep in 197 midlife women (M(age)  = 52.1, SD = 2.2). Delta EEG-HF-HRV correlations in nonrapid eye movement (NREM) sleep were modeled as whole-night averages and as continuous functions of time. The whole-night delta EEG-HF-HRV correlation was positive. The strongest correlations were observed during the first NREM sleep period preceding and following peak delta power. Time-varying correlations between delta EEG-HF-HRV were stronger in participants with sleep-disordered breathing and self-reported insomnia compared to healthy controls. The dynamic interplay between sleep and autonomic activity can be modeled across the night to examine within- and between-participant differences including individuals with and without sleep disorders.
authors.affiliation: Department of Statistics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
authors.forename: Scott D
authors.initials: SD
authors.lastname: Rothenberger
authors.forename: Robert T
authors.initials: RT
authors.lastname: Krafty
authors.forename: Briana J
authors.initials: BJ
authors.lastname: Taylor
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Cribbet
authors.forename: Julian F
authors.initials: JF
authors.lastname: Thayer
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Buysse
authors.forename: Howard M
authors.initials: HM
authors.lastname: Kravitz
authors.forename: Evan D
authors.initials: ED
authors.lastname: Buysse
authors.forename: Martica H
authors.initials: MH
authors.lastname: Hall
mesh_terms: D001341:Autonomic Nervous System / Q000502:physiology*; D001921:Brain / Q000502:physiology*; D004562:Electrocardiography; D004569:Electroencephalography; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008875:Middle Aged; D018670:Monitoring, Ambulatory; D017286:Polysomnography; D012890:Sleep / Q000502:physiology*
keywords: Delta EEG; HF-HRV; Sleep; Time-varying correlation