title: Comparison of CT colonography with conventional colonoscopy in patients with ulcerative colitis.
abstract: OBJECTIVE
  Patients with ulcerative colitis require recurrent conventional colonoscopy (CC) to define the extent of the disease. Computed tomography (CT) colonography (CTC) can be used as an alternative technique for studying the colon in these patients. The purpose of the study was to compare the findings of CTC to CC in patients with ulcerative colitis.
  
  
  METHODS
  Twenty patients proven to have ulcerative colitis on biopsy and in clinical remission state were enrolled in the study. They underwent CTC and CC within 1 week of each test. The investigators performing CTC and CC were blinded to the findings of each other. The chi-square test, kappa test, sensitivity, and specificity were used to compare the findings on CTC and CC. In addition, patient acceptance for both the procedures was compared.
  
  
  RESULTS
  Sensitivity and specificity on CTC for detecting granular appearance were 81.0% and 73.8%, respectively, and for pseudopolyps were 82.1% and 84.5%, respectively. Good correlation was seen between CTC and CC for detection of granular appearance and pseudopolyps. Loss of haustral folds, wall thickening, pericolonic vascularity, and pericolonic lymph nodes seen on CTC were found to correlate with intraluminal findings seen on CC. Patient acceptance for CTC was better than that for CC.
  
  
  CONCLUSIONS
  CTC can be used for evaluating patients with ulcerative colitis who are in remission.
authors.affiliation: Department of Radiodiagnosis, PGIMER, Chandigarh 160012, India.
authors.forename: Nidhi
authors.initials: N
authors.lastname: Prabhakar
authors.affiliation: Department of Radiodiagnosis, PGIMER, Chandigarh 160012, India. Electronic address: navkal2004@yahoo.com.
authors.forename: Naveen
authors.initials: N
authors.lastname: Kalra
authors.affiliation: Department of Gastroenterology, PGIMER, Chandigarh, India.
authors.forename: Deepak K
authors.initials: DK
authors.lastname: Bhasin
authors.affiliation: Department of Gastroenterology, PGIMER, Chandigarh, India.
authors.forename: Surinder S
authors.initials: SS
authors.lastname: Rana
authors.affiliation: Department of General Surgery, PGIMER, Chandigarh, India.
authors.forename: Vikas
authors.initials: V
authors.lastname: Gupta
authors.affiliation: Department of General Surgery, PGIMER, Chandigarh, India.
authors.forename: Rajinder
authors.initials: R
authors.lastname: Singh
authors.affiliation: Department of Radiodiagnosis, PGIMER, Chandigarh 160012, India.
authors.forename: Niranjan
authors.initials: N
authors.lastname: Khandelwal
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003093:Colitis, Ulcerative / Q000000981:diagnostic imaging*; D003106:Colon / Q000000981:diagnostic imaging; D023881:Colonography, Computed Tomographic / Q000379:methods*; D003113:Colonoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D055815:Young Adult
keywords: CT colonography; Colon; colonoscopy; ulcerative colitis