title: Smart pH-responsive upconversion nanoparticles for enhanced tumor cellular internalization and near-infrared light-triggered photodynamic therapy.
abstract: A smart pH-responsive photodynamic therapy system based on upconversion nanoparticle loaded PEG coated polymeric lipid vesicles (RB-UPPLVs) was designed and prepared. These RB-UPPLVs which are promising agents for deep cancer photodynamic therapy applications can achieve enhanced tumor cellular internalization and near-infrared light-triggered photodynamic therapy.
authors.affiliation: Institute of Nanobiotechnology, School of Life Sciences, School of Materials Science and Engineering, Tianjin University and Tianjin Key Laboratory of Composites and Functional Materials, Tianjin, 300072, PR China. jinchang@tju.edu.cn wanghj@tju.edu.cn.
authors.forename: Sheng
authors.initials: S
authors.lastname: Wang
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.forename: Chunhong
authors.initials: C
authors.lastname: Dong
authors.forename: Lin
authors.initials: L
authors.lastname: Su
authors.forename: Hanjie
authors.initials: H
authors.lastname: Wang
authors.forename: Jin
authors.initials: J
authors.lastname: Chang
mesh_terms: D006367:HeLa Cells; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007259:Infrared Rays; D008055:Lipids / Q000737:chemistry / Q000627:therapeutic use; D049449:Luminescence; D053758:Nanoparticles / Q000737:chemistry / Q000627:therapeutic use*; D009369:Neoplasms / Q000188:drug therapy*; D010778:Photochemotherapy / Q000379:methods; D011092:Polyethylene Glycols / Q000737:chemistry / Q000627:therapeutic use; D012395:Rose Bengal / Q000737:chemistry / Q000627:therapeutic use*
chemical_list: D008055:Lipids; D012395:Rose Bengal; D011092:Polyethylene Glycols