title: Antifungal effect of essential oil components against Aspergillus niger when loaded into silica mesoporous supports.
abstract: BACKGROUND
  Essential oil components (EOCs) are known for their antifungal properties; however, their high volatility limits their application as antimicrobial agents. Strategies used for controlling the volatility of EOCs include encapsulation or loading into porous materials. This study evaluated the in vitro antifungal activity of selected EOCs (carvacrol, cinnamaldehyde, eugenol and thymol) against the fungus Aspergillus niger when loaded into MCM-41 and β-cyclodextrin (β-CD).
  
  
  RESULTS
  Carvacrol and thymol in Mobil Composition of Matter No. 41 (MCM-41) displayed remarkable enhanced antifungal properties in comparison to the pure or β-CD-encapsulated EOCs. In fact, carvacrol and thymol were able to maintain antifungal activity and inhibit fungal growth for 30 days, suggesting better applicability of these EOCs as natural preservatives.
  
  
  CONCLUSIONS
  The sustained antifungal effect of EOCs encapsulated into silica mesoporous supports was described.
authors.affiliation: Department of Crop Production, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamýcká 129, Prague 6-Suchdol 165 21, Czech Republic.
authors.forename: Andrea
authors.initials: A
authors.lastname: Bernardos
authors.affiliation: Department of Quality of Agricultural Products, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamýcká 129, Prague 6-Suchdol 165 21, Czech Republic.
authors.forename: Teresa
authors.initials: T
authors.lastname: Marina
authors.affiliation: Research Team of Infochemicals, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nám. 2, 16610, Prague 6, Czech Republic.
authors.forename: Petr
authors.initials: P
authors.lastname: Žáček
authors.affiliation: Centro de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Unidad Mixta Universitat Politècnica de València, Universitat de València, Camino de Vera s/n, E-46022, Valencia, Spain.|Grupo de Investigación e Innovación Alimentaria (CUINA), Universitat Politècnica de València, Camino de Vera s/n, E-46022, Valencia, Spain.
authors.forename: Édgar
authors.initials: É
authors.lastname: Pérez-Esteve
authors.affiliation: Centro de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Unidad Mixta Universitat Politècnica de València, Universitat de València, Camino de Vera s/n, E-46022, Valencia, Spain.|CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Monforte de Lemos 3-5, Pabellón 11, 28029, Madrid, Spain.
authors.forename: Ramón
authors.initials: R
authors.lastname: Martínez-Mañez
authors.affiliation: Department of Inorganic Technology, Faculty of Chemical Technology, Institute of Chemical Technology, Technická 5, 16628, Prague 6, Czech Republic.
authors.forename: Miloslav
authors.initials: M
authors.lastname: Lhotka
authors.affiliation: Department of Quality of Agricultural Products, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamýcká 129, Prague 6-Suchdol 165 21, Czech Republic.
authors.forename: Lenka
authors.initials: L
authors.lastname: Kouřimská
authors.affiliation: Department of Crop Production, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamýcká 129, Prague 6-Suchdol 165 21, Czech Republic.
authors.forename: Josef
authors.initials: J
authors.lastname: Pulkrábek
authors.affiliation: Department of Quality of Agricultural Products, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamýcká 129, Prague 6-Suchdol 165 21, Czech Republic.
authors.forename: Pavel
authors.initials: P
authors.lastname: Klouček
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology*; D001234:Aspergillus niger / Q000187:drug effects* / Q000254:growth & development; D002934:Cinnamates / Q000737:chemistry / Q000494:pharmacology; D005516:Food Microbiology; D005519:Food Preservation / Q000379:methods*; D005520:Food Preservatives / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D039821:Monoterpenes / Q000737:chemistry / Q000494:pharmacology; D009822:Oils, Volatile / Q000737:chemistry / Q000494:pharmacology*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D010938:Plant Oils / Q000737:chemistry / Q000494:pharmacology; D012822:Silicon Dioxide; D014835:Volatilization; D047392:beta-Cyclodextrins
chemical_list: D000935:Antifungal Agents; D002934:Cinnamates; D005520:Food Preservatives; C509968:MCM-41; D039821:Monoterpenes; D009822:Oils, Volatile; D010936:Plant Extracts; D010938:Plant Oils; D047392:beta-Cyclodextrins; D012822:Silicon Dioxide
keywords: antifungal activity; controlled release; cyclodextrin; encapsulation; essential oil components; mesoporous silica materials