title: Genomic analyses confirm close relatedness between Rhodococcus defluvii and Rhodococcus equi (Rhodococcus hoagii).
abstract: Rhodococcus defluvii strain Ca11(T) was isolated from a bioreactor involved in extensive phosphorus removal. We have sequenced the whole genome of this strain, and our comparative genomic and phylogenetic analyses confirm its close relatedness with Rhodococcus equi (Rhodococcus hoagii) strains, which share >80 % of the gene content. The R. equi virulence plasmid is absent though most of the chromosomal R. equi virulence-associated genes are present in R. defluvii Ca11(T). These data suggest that although R. defluvii is an environmental organism, it has the potential to colonize animal hosts.
authors.affiliation: Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, NE1 8ST, UK, vartul.sangal@northumbria.ac.uk.
authors.forename: Vartul
authors.initials: V
authors.lastname: Sangal
authors.forename: Amanda L
authors.initials: AL
authors.lastname: Jones
authors.forename: Michael
authors.initials: M
authors.lastname: Goodfellow
authors.forename: Paul A
authors.initials: PA
authors.lastname: Hoskisson
authors.forename: Peter
authors.initials: P
authors.lastname: Kämpfer
authors.forename: Iain C
authors.initials: IC
authors.lastname: Sutcliffe
mesh_terms: D001483:Base Sequence; D005798:Genes, Bacterial; D016680:Genome, Bacterial; D023281:Genomics; D008969:Molecular Sequence Data; D010802:Phylogeny; D010957:Plasmids; D012240:Rhodococcus / Q000145:classification* / Q000235:genetics* / Q000472:pathogenicity; D016929:Rhodococcus equi / Q000145:classification* / Q000235:genetics* / Q000472:pathogenicity; D014774:Virulence / Q000235:genetics