title: Ni-Catalyzed α-arylation of esters and amides with phenol derivatives.
abstract: A nickel-catalyzed α-arylation of esters and amides with phenol derivatives has been accomplished. In the presence of our unique nickel catalyst, prepared in situ from Ni(cod)2, 3,4-bis(dicyclohexylphosphino)thiophene (dcypt), and K3PO4, various esters and amides undergo α-arylation with O-arylpivalates or O-arylcarbamates to afford the corresponding coupling products. The thus obtained α-aryl esters and amides are useful precursors of privileged motifs such as α-arylcarboxylic acids and β-arylamines.
authors.affiliation: Organisch-Chemisches Institut, Westfälische Wilhelms-Universität, Corrensstraße 40, 48149 Münster, Germany.
authors.forename: Eva
authors.initials: E
authors.lastname: Koch
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Takise
authors.forename: Armido
authors.initials: A
authors.lastname: Studer
authors.forename: Junichiro
authors.initials: J
authors.lastname: Yamaguchi
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Itami
mesh_terms: D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D004952:Esters; D009532:Nickel / Q000737:chemistry*; D019800:Phenol / Q000737:chemistry*
chemical_list: D000577:Amides; D004952:Esters; D019800:Phenol; D009532:Nickel