title: High-dose-rate Interstitial Brachytherapy Boost with a Pedicled Latissimus Dorsi Myocutaneous Flap for Myxofibrosarcoma of the Arm.
abstract: A 71-year-old man was found to have a 7.4 × 2.9 × 7.0 cm myxofibrosarcoma of the right medial arm close to neurovascular structures. He received 50 Gray (Gy) of preoperative external beam radiation. Radical resection resulted in a 15 × 10 cm defect. Nine brachytherapy catheters were placed, and a pedicled latissimus dorsi myocutaneous flap was used in reconstruction. Final pathology confirmed myxofibrosarcoma, high grade. The tumor was <1 mm from 2 margins. A total of 17.5 Gy of brachytherapy was delivered to the surgical bed from postoperative days 7 to 9. The flap developed fat necrosis distally which eventually required surgical debridement on postoperative day 58. It subsequently healed well and maintained good function of the limb. The patient remains under surveillance without evidence of recurrence.
authors.affiliation: Harvard Medical School, Boston, Mass.; Division of Plastic Surgery and Department of Surgery, Brigham and Women's Hospital, Boston, Mass.; Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, Boston, Mass.; and Department of Radiation Oncology, Brigham and Women's Hospital, Boston, Mass.
authors.forename: Jordan D
authors.initials: JD
authors.lastname: Lane
authors.affiliation: Harvard Medical School, Boston, Mass.; Division of Plastic Surgery and Department of Surgery, Brigham and Women's Hospital, Boston, Mass.; Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, Boston, Mass.; and Department of Radiation Oncology, Brigham and Women's Hospital, Boston, Mass.
authors.forename: Bohdan
authors.initials: B
authors.lastname: Pomahac
authors.affiliation: Harvard Medical School, Boston, Mass.; Division of Plastic Surgery and Department of Surgery, Brigham and Women's Hospital, Boston, Mass.; Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, Boston, Mass.; and Department of Radiation Oncology, Brigham and Women's Hospital, Boston, Mass.
authors.forename: Chandrajit P
authors.initials: CP
authors.lastname: Raut
authors.affiliation: Harvard Medical School, Boston, Mass.; Division of Plastic Surgery and Department of Surgery, Brigham and Women's Hospital, Boston, Mass.; Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, Boston, Mass.; and Department of Radiation Oncology, Brigham and Women's Hospital, Boston, Mass.
authors.forename: Elizabeth H
authors.initials: EH
authors.lastname: Baldini
authors.affiliation: Harvard Medical School, Boston, Mass.; Division of Plastic Surgery and Department of Surgery, Brigham and Women's Hospital, Boston, Mass.; Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, Boston, Mass.; and Department of Radiation Oncology, Brigham and Women's Hospital, Boston, Mass.
authors.forename: Phillip M
authors.initials: PM
authors.lastname: Devlin