title: Comparison of chromogenic media for recovery of carbapenemase-producing enterobacteriaceae (CPE) and evaluation of CPE prevalence at a tertiary care academic medical center.
abstract: We evaluated the performance characteristics of chromID CARBA and HardyCHROM Carbapenemase for the detection of carbapenemase-producing Enterobacteriaceae (CPE). A CPE prevalence study was conducted using chromID CARBA; this demonstrated that in low-prevalence settings, CPE screening agars may lack specificity, and confirmation of putative isolates is necessary.
authors.affiliation: Department of Pathology and Immunology, Division of Laboratory and Genomic Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
authors.forename: Morgan A
authors.initials: MA
authors.lastname: Pence
authors.affiliation: Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, Missouri, USA.
authors.forename: Tiffany
authors.initials: T
authors.lastname: Hink
authors.affiliation: Department of Pathology and Immunology, Division of Laboratory and Genomic Medicine, Washington University School of Medicine, St. Louis, Missouri, USA cburnham@path.wustl.edu.
authors.forename: Carey-Ann D
authors.identifier: http://orcid.org/0000-0002-1137-840X
authors.initials: CA
authors.lastname: Burnham
mesh_terms: D000046:Academic Medical Centers; D001426:Bacterial Proteins / Q000378:metabolism*; D002863:Chromogenic Compounds / Q000378:metabolism*; D003470:Culture Media / Q000737:chemistry*; D004755:Enterobacteriaceae / Q000201:enzymology* / Q000254:growth & development / Q000302:isolation & purification*; D004756:Enterobacteriaceae Infections / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D015995:Prevalence; D012680:Sensitivity and Specificity; D063128:Tertiary Health Care; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D002863:Chromogenic Compounds; D003470:Culture Media; D001618:beta-Lactamases; C063912:carbapenemase