title: Bilateral invasive duct carcinoma, phyllodes tumor and multiple fibroadenomas of breast associated with lymph node metastases - rare coexistence.
abstract: Concomitant occurrence of phyllodes tumor with an in situ or invasive carcinoma in the breast is an uncommon phenomenon and has been reported sparingly. We describe a rare case of simultaneous bilateral intraductal and infiltrating duct carcinoma with coexisting fibroadenomas and phyllodes tumor. To the best of our knowledge, only 19 cases of invasive carcinoma with phyllodes tumor have been reported so far and lymph node metastases has been described only once. A 43 year-old woman presented with multiple bilateral breast lumps. Core biopsies revealed phyllodes tumor in the right breast and invasive duct carcinoma of the left breast. Simple mastectomy done for right breast showed foci of invasive carcinoma arising in phyllodes tumor. Metastasis was detected in the left axillary lymph nodes. This case is being reported to create awareness of this rare transformation, which has significant prognostic and therapeutic implications.
authors.affiliation: Department of Pathology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, 110060 India.
authors.forename: Sunila
authors.initials: S
authors.lastname: Jain
authors.affiliation: Department of Pathology, Sir Ganga Ram Hospital, New Delhi, India.
authors.forename: Ramneet
authors.initials: R
authors.lastname: Kaur
authors.affiliation: Department of Surgical Oncology, Sir Ganga Ram Hospital, New Delhi, India.
authors.forename: Rajeev
authors.initials: R
authors.lastname: Agarwal
authors.affiliation: Department of Pathology, Sir Ganga Ram Hospital, New Delhi, India.
authors.forename: Prem
authors.initials: P
authors.lastname: Chopra
keywords: Breast; Carcinoma; Invasive; Phyllodes; Tumor