title: Impaired development of fetal serotonergic neurons in intrauterine growth restricted baboons.
abstract: We studied development of the fetal serotonergic central nervous system in a baboon, non-human primate model of intrauterine growth restriction (IUGR). Fetal (90% of full-term) IUGR brains were comparable in size to controls, but have reduced expression of serotonergic proteins and mRNAs, as well as having fewer serotonergic neurons.
authors.affiliation: Department of Physiology, and Pharmacology. University of Texas Health Science Center, San Antonio, TX 78229-3900.
authors.forename: Wenrui
authors.initials: W
authors.lastname: Ye
authors.affiliation: Department of OBGYN and Center for Pregnancy and Newborn Research, and Pharmacology. University of Texas Health Science Center, San Antonio, TX 78229-3900.
authors.forename: Lynn
authors.initials: L
authors.lastname: Xie
authors.affiliation: Department of OBGYN and Center for Pregnancy and Newborn Research, and Pharmacology. University of Texas Health Science Center, San Antonio, TX 78229-3900.
authors.forename: Cun
authors.initials: C
authors.lastname: Li
authors.affiliation: Department of OBGYN and Center for Pregnancy and Newborn Research, and Pharmacology. University of Texas Health Science Center, San Antonio, TX 78229-3900.
authors.forename: Peter W
authors.initials: PW
authors.lastname: Nathanielsz
authors.affiliation: Department of Cellular & Structural Biology, and Pharmacology. University of Texas Health Science Center, San Antonio, TX 78229-3900.
authors.forename: Brent J
authors.initials: BJ
authors.lastname: Thompson
keywords: IUGR; Serotonin; brain development; fetus; maternal nutrition