title: A simple and robust preparation of N-acetylindoxyls: precursors for indigogenic substrates.
abstract: A generalised, simple and efficient synthesis of N-acetyl-5-bromo-4-chloroindoxyl and related analogues required for the synthesis of indigogenic substrates to probe for biological activities is reported. The method is both synthetically and operationally simple and represents a significant improvement on existing methods.
authors.affiliation: School of Chemistry and Biochemistry, The University of Western Australia, Crawley, WA 6009, Australia. keith.stubbs@uwa.edu.au.
authors.forename: Michael N
authors.initials: MN
authors.lastname: Gandy
authors.forename: Lindsay T
authors.initials: LT
authors.lastname: Byrne
authors.forename: Keith A
authors.initials: KA
authors.lastname: Stubbs
mesh_terms: D001565:Benzoates / Q000737:chemistry; D004396:Coloring Agents / Q000138:chemical synthesis*; D007203:Indigo Carmine / Q000031:analogs & derivatives / Q000138:chemical synthesis*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001565:Benzoates; D004396:Coloring Agents; D007211:Indoles; C053640:indoxyl acetate; D007203:Indigo Carmine