title: Structure-Function Relationship between Frequency-Doubling Technology Perimetry and Optical Coherence Tomography in Glaucoma.
abstract: Purpose: To assess the relationship between the retinal nerve fibre layer (RNFL) thickness and the frequency-doubling technology perimetry (FDT) outcome. Methods: Sixty-two healthy individuals and 72 glaucoma patients were prospectively selected. All participants underwent a reliable FDT and optical coherence tomography (OCT). Pearson correlations were calculated between the unlogged threshold values of FDT and RNFL thicknesses measured by OCT. Results: Mild to moderate correlations were found between a few points from FDT and RNFL thicknesses in the vertical axis. The nasal superior area of FDT and the RNFL thickness at the 7-o'clock position had the strongest correlation (0.434, p < 0.001). Conclusions: The poor agreement between FDT and OCT parameters suggests that both instruments assess different characteristics of glaucomatous optic neuropathy. The map obtained validates previously reported clinical findings and contributes to a better understanding of the structure-function relationship in glaucoma. © 2014 S. Karger AG, Basel.
authors.affiliation: Ophthalmology Department, Miguel Servet University Hospital, Aragon Health Sciences Institute, Zaragoza, Spain.
authors.forename: Isabel
authors.initials: I
authors.lastname: Fuertes-Lazaro
authors.forename: Ana
authors.initials: A
authors.lastname: Sanchez-Cano
authors.forename: Antonio
authors.initials: A
authors.lastname: Ferreras
authors.forename: Blanca
authors.initials: B
authors.lastname: Ferrandez
authors.forename: Pilar
authors.initials: P
authors.lastname: Calvo
authors.forename: Beatriz
authors.initials: B
authors.lastname: Abadia
authors.forename: Sofia
authors.initials: S
authors.lastname: Otin
authors.forename: Luis E
authors.initials: LE
authors.lastname: Pablo