title: Complete mitochondrial genome sequence and mutations of the hepatocellular carcinoma model inbred Sprague-Dawley strain.
abstract: In the present work we undertook the complete mitochondrial genome sequencing of an important hepatocellular carcinoma model inbred Sprague-Dawley strain for the first time. The total length of the mitogenome was 16,308 bp. It harbored 13 protein-coding genes, two ribosomal RNA genes, 22 transfer RNA genes and one non-coding control region (D-loop region). The mutation events were also reported.
authors.affiliation: a Clinical Laboratory , Fuzhou General Hospital of Nanjing Military Area Command of Chinese PLA , Fuzhou , China and.
authors.forename: Sheng-Hang
authors.initials: SH
authors.lastname: Zhang
authors.affiliation: b Department of Hepatobiliary Medicine , Fuzhou General Hospital of Nanjing Military Area Command of Chinese PLA , Fuzhou , China.
authors.forename: Dong-Liang
authors.initials: DL
authors.lastname: Li
authors.affiliation: b Department of Hepatobiliary Medicine , Fuzhou General Hospital of Nanjing Military Area Command of Chinese PLA , Fuzhou , China.
authors.forename: Zhi-Qiang
authors.initials: ZQ
authors.lastname: Zhang
authors.affiliation: b Department of Hepatobiliary Medicine , Fuzhou General Hospital of Nanjing Military Area Command of Chinese PLA , Fuzhou , China.
authors.forename: Xia
authors.initials: X
authors.lastname: Zhang
authors.affiliation: b Department of Hepatobiliary Medicine , Fuzhou General Hospital of Nanjing Military Area Command of Chinese PLA , Fuzhou , China.
authors.forename: Li-Rong
authors.initials: LR
authors.lastname: Cai
mesh_terms: D000818:Animals; D006528:Carcinoma, Hepatocellular; D004272:DNA, Mitochondrial / Q000737:chemistry / Q000235:genetics; D004195:Disease Models, Animal; D005260:Female; D054629:Genome, Mitochondrial / Q000235:genetics*; D006801:Humans; D008113:Liver Neoplasms; D008928:Mitochondria / Q000235:genetics; D024101:Mitochondrial Proteins / Q000235:genetics; D009154:Mutation; D012335:RNA, Ribosomal / Q000235:genetics; D012343:RNA, Transfer / Q000235:genetics; D051381:Rats; D017207:Rats, Sprague-Dawley / Q000235:genetics*; D017422:Sequence Analysis, DNA
chemical_list: D004272:DNA, Mitochondrial; D024101:Mitochondrial Proteins; D012335:RNA, Ribosomal; D012343:RNA, Transfer
keywords: Genome; hepatocellular carcinoma; mitochondrion