title: Taming hazardous chemistry in flow: the continuous processing of diazo and diazonium compounds.
abstract: The synthetic utilities of the diazo and diazonium groups are matched only by their reputation for explosive decomposition. Continuous processing technology offers new opportunities to make and use these versatile intermediates at a range of scales with improved safety over traditional batch processes. In this minireview, the state of the art in the continuous flow processing of reactive diazo and diazonium species is discussed.
authors.affiliation: Department of Chemistry, Analytical and Biological Chemistry Research Facility, Synthesis and Solid State Pharmaceutical Centre, University College Cork (Ireland).
authors.forename: Benjamin J
authors.initials: BJ
authors.lastname: Deadman
authors.forename: Stuart G
authors.initials: SG
authors.lastname: Collins
authors.forename: Anita R
authors.initials: AR
authors.lastname: Maguire
mesh_terms: D002384:Catalysis; D003978:Diazomethane / Q000138:chemical synthesis / Q000737:chemistry; D003979:Diazonium Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry
chemical_list: D003979:Diazonium Compounds; D003978:Diazomethane; D012238:Rhodium
keywords: continuous processing; diazocarbonyls; diazomethane; diazonium ions; flow chemistry