title: Actinobacteria mediated synthesis of nanoparticles and their biological properties: A review.
abstract: Nanotechnology is gaining tremendous attention in the present century due to its expected impact on many important areas such as medicine, energy, electronics, and space industries. In this context, actinobacterial biosynthesis of nanoparticles is a reliable, eco-friendly, and important aspect of green chemistry approach that interconnects microbial biotechnology and nanobiotechnology. Antibiotics produced by actinobacteria are popular in almost all the therapeutic measures and it is known that these microbes are also helpful in the biosynthesis of nanoparticles with good surface and size characteristics. In fact, actinobacteria are efficient producers of nanoparticles that show a range of biological properties, namely, antibacterial, antifungal, anticancer, anti-biofouling, anti-malarial, anti-parasitic, antioxidant, etc. This review describes the potential use of the actinobacteria as the novel sources for the biosynthesis of nanoparticles with improved biomedical applications.
authors.affiliation: a Department of Chemistry , Marine Bioprocess Research Centre, Pukyong National University , Busan , Republic of Korea and.
authors.forename: Panchanathan
authors.initials: P
authors.lastname: Manivasagan
authors.affiliation: a Department of Chemistry , Marine Bioprocess Research Centre, Pukyong National University , Busan , Republic of Korea and.
authors.forename: Jayachandran
authors.initials: J
authors.lastname: Venkatesan
authors.affiliation: b Faculty of Marine Sciences , CAS in Marine Biology , Chidambaram , India.
authors.forename: Kannan
authors.initials: K
authors.lastname: Sivakumar
authors.affiliation: a Department of Chemistry , Marine Bioprocess Research Centre, Pukyong National University , Busan , Republic of Korea and.
authors.forename: Se-Kwon
authors.initials: SK
authors.lastname: Kim
mesh_terms: D039903:Actinobacteria / Q000502:physiology*; D000890:Anti-Infective Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D001709:Biotechnology; D005110:Extracellular Space / Q000378:metabolism; D006801:Humans; D042541:Intracellular Space / Q000378:metabolism; D053758:Nanoparticles / Q000737:chemistry / Q000145:classification / Q000378:metabolism* / Q000648:ultrastructure; D036103:Nanotechnology
chemical_list: D000890:Anti-Infective Agents; D000970:Antineoplastic Agents; D000975:Antioxidants
keywords: Actinobacteria; biomedical applications; nanoparticles; nanotechnology