title: Dose reduction in pediatric abdominal CT: use of iterative reconstruction techniques across different CT platforms.
abstract: Dose reduction in children undergoing CT scanning is an important priority for the radiology community and public at large. Drawbacks of radiation reduction are increased image noise and artifacts, which can affect image interpretation. Iterative reconstruction techniques have been developed to reduce noise and artifacts from reduced-dose CT examinations, although reconstruction algorithm, magnitude of dose reduction and effects on image quality vary. We review the reconstruction principles, radiation dose potential and effects on image quality of several iterative reconstruction techniques commonly used in clinical settings, including 3-D adaptive iterative dose reduction (AIDR-3D), adaptive statistical iterative reconstruction (ASIR), iDose, sinogram-affirmed iterative reconstruction (SAFIRE) and model-based iterative reconstruction (MBIR). We also discuss clinical applications of iterative reconstruction techniques in pediatric abdominal CT.
authors.affiliation: Harvard Medical School, MGH Imaging, Massachusetts General Hospital, 25 New Chardon St., 4th floor, Boston, MA, 02114, USA, rkhawaja@mgh.harvard.edu.
authors.forename: Ranish Deedar Ali
authors.initials: RD
authors.lastname: Khawaja
authors.forename: Sarabjeet
authors.initials: S
authors.lastname: Singh
authors.forename: Alexi
authors.initials: A
authors.lastname: Otrakji
authors.forename: Atul
authors.initials: A
authors.lastname: Padole
authors.forename: Ruth
authors.initials: R
authors.lastname: Lim
authors.forename: Katherine
authors.initials: K
authors.lastname: Nimkin
authors.forename: Sjirk
authors.initials: S
authors.lastname: Westra
authors.forename: Mannudeep K
authors.initials: MK
authors.lastname: Kalra
authors.forename: Michael S
authors.initials: MS
authors.lastname: Gee
mesh_terms: D000293:Adolescent; D000465:Algorithms; D016477:Artifacts; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional; D007223:Infant; D008297:Male; D011829:Radiation Dosage; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D011860:Radiography, Abdominal / Q000379:methods*; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed / Q000379:methods*