title: [A case of stage IV breast cancer successfully treated over 1 year with eribulin as fourth-line systemic chemotherapy].
abstract: A 59-year-old woman with an exudative, reddish bilateral breast tumor and dyspnea visited our hospital. She was diagnosed as having scirrhous carcinoma with metastasis to the liver and pleural effusion, designated as Stage IV, hormone receptor positive, and human epidermal growth factor receptor-2 (HER2) negative. Systemic chemotherapy (3 regimens) and endocrine therapy (5 regimens) were administered for a total of 5 years 7 months. Eribulin was administered as fourth line systemic chemotherapy. The pleural effusion reduced and dyspnea improved. Her status was maintained for 1 year 3 months. This case suggests that eribulin may provide long-term survival and maintenance of quality of life (QOL) in metastatic breast cancer patients.
authors.affiliation: Dept. of Surgery, Yamagata Prefectural Shinjo Hospital.
authors.forename: Tomoharu
authors.initials: T
authors.lastname: Ishiyama
authors.forename: Akira
authors.initials: A
authors.lastname: Jinguu
authors.forename: Hidekazu
authors.initials: H
authors.lastname: Matsumoto
authors.forename: Jirou
authors.initials: J
authors.lastname: Kikuchi
authors.forename: Tomonobu
authors.initials: T
authors.lastname: Suzuki
mesh_terms: D002293:Adenocarcinoma, Scirrhous / Q000188:drug therapy*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D005663:Furans / Q000627:therapeutic use*; D006801:Humans; D007659:Ketones / Q000627:therapeutic use*; D008875:Middle Aged; D009367:Neoplasm Staging; D016879:Salvage Therapy; D000095662:Polyether Polyketides
chemical_list: D005663:Furans; D007659:Ketones; C490954:eribulin; D000095662:Polyether Polyketides