title: [Charles Miller Fisher: the grandmaster of neurological observation].
abstract: Charles Miller Fisher is widely regarded as the father of modern stroke neurology. He discovered almost all pathomechanisms of cerebral infarction, including embolism from atrial fibrillation, carotid artery disease, and lacunar infarcts and their syndromes, by the most meticulous clinico-pathological observations. Moreover, his work provided the basis for treatments such as anticoagulation, antiplatelet therapy, and carotid endarterectomy. He also contributed greatly to several topics of General Neurology; for example, migraine, normal pressure hydrocephalus, and Miller Fisher syndrome. In his late years, he tried to expand the neurological field to the more complex disorders of human behavior, including hysteria, dementia, and ill-defined pain syndromes. He thus became known as the grandmaster of refined neurological observation. His lifelong detailed studies were crucially important in helping neurologists all over the world recognize disorders and syndromes that had not previously been understood.
authors.affiliation: Department of Neurology, Kameda Medical Center.
authors.forename: Toshio
authors.initials: T
authors.lastname: Fukutake
mesh_terms: D001519:Behavior / Q000502:physiology*; D002170:Canada; D002340:Carotid Artery Diseases / Q000175:diagnosis / Q000266:history*; D003704:Dementia / Q000503:physiopathology; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D019846:Miller Fisher Syndrome / Q000175:diagnosis / Q000266:history*; D009462:Neurology / Q000266:history*; D020521:Stroke / Q000175:diagnosis / Q000266:history*