title: [Advances in porcine miRNAome].
abstract: MicroRNA (miRNA), a class of non-coding RNA (about 22 nt), widely exists in different organisms and plays an important role in growth, development, and apoptosis. Recently, many studies have shown that miRNAs serve as a regulatory mechanism in mediating the development of pig muscle, fat, reproductive and immunity traits. The next-generation of high-throughput sequencing technology plays a critical role on finding new miRNAs and identifying their different expressions in pig. In this review, we summarize the application of the next-generation of high-throughput sequencing technology in the study of pig miRNAs as well as the regulatory roles of several important miRNAs in fat metabolism, muscle development, oocyte maturation and development of B cells and T cells. This review will provide insight into the research on pig miRNAs, and some ideas on how to improve pork quality, growth, reproductive and immunity performance.
authors.affiliation: 1. College of Animal Science Technology, Hunan Agricultural University, Changsha 410128, China; 2. Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal, Changsha 410128, China;
authors.forename: Maoliang
authors.initials: M
authors.lastname: Ran
authors.affiliation: 1. College of Animal Science Technology, Hunan Agricultural University, Changsha 410128, China; 2. Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal, Changsha 410128, China;
authors.forename: Bin
authors.initials: B
authors.lastname: Chen
authors.affiliation: 1. Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China; 2. University of the Chinese Academy of Sciences, Beijing 100049, China;
authors.forename: Jie
authors.initials: J
authors.lastname: Yin
authors.affiliation: 1. College of Animal Science Technology, Hunan Agricultural University, Changsha 410128, China; 2. Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal, Changsha 410128, China;
authors.forename: Anqi
authors.initials: A
authors.lastname: Yang
authors.affiliation: 1. College of Animal Science Technology, Hunan Agricultural University, Changsha 410128, China; 2. Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal, Changsha 410128, China;
authors.forename: Zhi
authors.initials: Z
authors.lastname: Li
authors.affiliation: 1. College of Animal Science Technology, Hunan Agricultural University, Changsha 410128, China; 2. Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal, Changsha 410128, China;
authors.forename: Ming
authors.initials: M
authors.lastname: Jiang
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D000818:Animals; D019295:Computational Biology / Q000379:methods*; D008214:Lymphocytes / Q000166:cytology; D035683:MicroRNAs / Q000235:genetics*; D024510:Muscle Development / Q000235:genetics; D009865:Oocytes / Q000166:cytology; D013552:Swine / Q000235:genetics* / Q000254:growth & development / Q000276:immunology / Q000378:metabolism
chemical_list: D035683:MicroRNAs