title: Multicolor imaging and the anticancer effect of a bifunctional silica nanosystem based on the complex of graphene quantum dots and hypocrellin A.
abstract: An effective theranostic platform based on porous silica nanoparticles encapsulated with the complex of a photodynamic anticancer drug and graphene quantum dots (GQDs), with the bifunction of multicolor imaging and satisfactory photo-induced anticancer activity, was successfully designed and prepared for in vitro photodynamic therapy (PDT) of superficial cancer.
authors.affiliation: College of Chemistry and Materials Science, Analysis and Testing Centre, Jiangsu Key Laboratory of Biofunctional Materials, Jiangsu Collaborative Innovation Centre of Biomedical Functional Materials, Key Laboratory of Applied Photochemistry, Nanjing Normal University, Wenyuan Road No. 1, Nanjing, China. zhoujiahong@njnu.edu.cn shwei@njnu.edu.cn.
authors.forename: Lin
authors.initials: L
authors.lastname: Zhou
authors.forename: Lin
authors.initials: L
authors.lastname: Zhou
authors.forename: Xuefeng
authors.initials: X
authors.lastname: Ge
authors.forename: Jiahong
authors.initials: J
authors.lastname: Zhou
authors.forename: Shaohua
authors.initials: S
authors.lastname: Wei
authors.forename: Jian
authors.initials: J
authors.lastname: Shen
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D006108:Graphite / Q000627:therapeutic use; D006367:HeLa Cells; D006801:Humans; D053758:Nanoparticles / Q000627:therapeutic use; D009369:Neoplasms / Q000175:diagnosis* / Q000188:drug therapy*; D061848:Optical Imaging; D010569:Perylene / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D019800:Phenol; D010778:Photochemotherapy / Q000379:methods; D045663:Quantum Dots / Q000627:therapeutic use; D011809:Quinones / Q000008:administration & dosage / Q000627:therapeutic use*; D012822:Silicon Dioxide / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D011809:Quinones; D019800:Phenol; D010569:Perylene; D012822:Silicon Dioxide; D006108:Graphite; C048388:hypocrellin A