title: Bone regeneration around implants placed in fresh extraction sockets covered with a dual-layer PTFE/collagen membrane: an experimental study in dogs.
abstract: This study investigated whether the use of a dual-layer polytetrafluoroethylene (PTFE)/porcine-derived bioresorbable pericardium membrane enhances the osseointegration around implants compared to a single-layer porcine-derived bioresorbable pericardium membrane and a no-membrane control group. Endosseous implants were placed in the fresh extraction sockets of beagles. At 6 weeks, bone loss and apical soft tissue migration occurred in the control group, whereas bone successfully formed to the neck of the implant for the single-layer porcine-derived bioresorbable pericardium membrane group. The dual-layer PTFE/ porcine-derived bioresorbable pericardium membrane showed bone growth coronal to the neck of the implant. Bone-to-implant contact and buccal bone loss were respectively higher and lower relative to the single-layer but not statistically different.
authors.forename: Nick
authors.initials: N
authors.lastname: Tovar
authors.forename: Ryo
authors.initials: R
authors.lastname: Jimbo
authors.forename: Charles
authors.initials: C
authors.lastname: Marin
authors.forename: Lukasz
authors.initials: L
authors.lastname: Witek
authors.forename: Marcelo
authors.initials: M
authors.lastname: Suzuki
authors.forename: Estevam A
authors.initials: EA
authors.lastname: Bonfante
authors.forename: Paulo G
authors.initials: PG
authors.lastname: Coelho
mesh_terms: D020341:Absorbable Implants; D000818:Animals; D001861:Bone Regeneration / Q000502:physiology*; D003094:Collagen; D019250:Dental Implants, Single-Tooth; D004285:Dogs; D008334:Mandible; D008567:Membranes, Artificial; D016348:Osseointegration / Q000502:physiology*; D010496:Pericardium; D011138:Polytetrafluoroethylene; D013552:Swine; D014081:Tooth Extraction; D020390:Tooth Socket / Q000601:surgery*
chemical_list: D008567:Membranes, Artificial; D011138:Polytetrafluoroethylene; D003094:Collagen