title: Flavivirus-mosquito interactions.
abstract: The Flavivirus genus is in the family Flaviviridae and is comprised of more than 70 viruses. These viruses have a broad geographic range, circulating on every continent except Antarctica. Mosquito-borne flaviviruses, such as yellow fever virus, dengue virus serotypes 1-4, Japanese encephalitis virus, and West Nile virus are responsible for significant human morbidity and mortality in affected regions. This review focuses on what is known about flavivirus-mosquito interactions and presents key data collected from the field and laboratory-based molecular and ultrastructural evaluations.
authors.affiliation: Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA. kmhorne@ksu.edu.
authors.forename: Yan-Jang S
authors.initials: YJ
authors.lastname: Huang
authors.affiliation: Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA. kmhorne@ksu.edu.
authors.forename: Stephen
authors.initials: S
authors.lastname: Higgs
authors.affiliation: Biosecurity Research Institute, Kansas State University, Manhattan, KS 66506, USA. kmhorne@ksu.edu.
authors.forename: Kate McElroy
authors.initials: KM
authors.lastname: Horne
authors.affiliation: Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA. kmhorne@ksu.edu.
authors.forename: Dana L
authors.initials: DL
authors.lastname: Vanlandingham
mesh_terms: D000818:Animals; D009033:Culicidae / Q000276:immunology / Q000821:virology*; D005416:Flavivirus / Q000276:immunology / Q000502:physiology*; D018177:Flavivirus Infections / Q000453:epidemiology / Q000635:transmission; D054884:Host-Pathogen Interactions; D006801:Humans; D007303:Insect Vectors / Q000276:immunology / Q000821:virology*