title: Constitutive phosphorylation of the active Notch1 intracellular domain in chronic lymphocytic leukemia cells with NOTCH1 mutation.
authors.affiliation: Department of Experimental Medicine, Biosciences and Medical Embryology Section, University of Perugia, Perugia, Italy.
authors.forename: F
authors.initials: F
authors.lastname: De Falco
authors.affiliation: Department of Experimental Medicine, Biosciences and Medical Embryology Section, University of Perugia, Perugia, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Sabatini
authors.affiliation: Department of Medicine, Hematology and Clinical Immunology Section, University of Perugia, Perugia, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Falzetti
authors.affiliation: Department of Life, Health and Environmental Sciences, Hematology Section, University of L'Aquila, L'Aquila, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Di Ianni
authors.affiliation: Department of Medicine, Hematology and Clinical Immunology Section, University of Perugia, Perugia, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Sportoletti
authors.affiliation: Department of Medicine, Hematology and Clinical Immunology Section, University of Perugia, Perugia, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Baldoni
authors.affiliation: Department of Medicine, Hematology and Clinical Immunology Section, University of Perugia, Perugia, Italy.
authors.forename: B
authors.initials: B
authors.lastname: Del Papa
authors.affiliation: Department of Molecular Medicine, University La Sapienza, Rome, Italy.
authors.forename: I
authors.initials: I
authors.lastname: Screpanti
authors.affiliation: Department of Experimental Medicine, Biosciences and Medical Embryology Section, University of Perugia, Perugia, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Marconi
authors.affiliation: Department of Experimental Medicine, Biosciences and Medical Embryology Section, University of Perugia, Perugia, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Rosati
mesh_terms: D000483:Alleles; D047390:Casein Kinase II / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D015973:Gene Expression Regulation, Leukemic; D005787:Gene Frequency; D038362:Glycogen Synthase Kinase 3 / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D000071679:Glycogen Synthase Kinase 3 beta; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D009154:Mutation; D019869:Phosphatidylinositol 3-Kinases / Q000235:genetics / Q000378:metabolism; D000081082:Phosphoinositide-3 Kinase Inhibitors; D010766:Phosphorylation; D047428:Protein Kinase Inhibitors / Q000494:pharmacology; D017434:Protein Structure, Tertiary; D051057:Proto-Oncogene Proteins c-akt / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D051881:Receptor, Notch1 / Q000235:genetics* / Q000378:metabolism
chemical_list: D047390:Casein Kinase II; D038362:Glycogen Synthase Kinase 3; D000071679:Glycogen Synthase Kinase 3 beta; D019869:Phosphatidylinositol 3-Kinases; D000081082:Phosphoinositide-3 Kinase Inhibitors; D047428:Protein Kinase Inhibitors; D051057:Proto-Oncogene Proteins c-akt; D051881:Receptor, Notch1; C497761:NOTCH1 protein, human