title: Acute effects of ultrafiltration on aortic mechanical properties determined by measurement of pulse wave velocity and pulse propagation time in hemodialysis patients.
abstract: OBJECTIVE
  The effects of acute hemodialysis session on pulse wave velocity are conflicting. The aim of the current study was to assess the acute effects of ultrafiltration on the aortic mechanical properties using carotid-femoral (aortic) pulse wave velocity and pulse propagation time.
  
  
  METHODS
  A total of 26 (12 women, 14 men) consecutive patients on maintenance hemodialysis (mean dialysis duration: 40.7±25.6 (4-70) months) and 29 healthy subjects (13 women, 16 men) were included in this study. Baseline blood pressure, carotid-femoral (aortic) pulse wave velocity, and pulse propagation time were measured using a Complior Colson device (Createch Industrie, France) before and immediately after the end of the dialysis session.
  
  
  RESULTS
  While systolic blood pressure, diastolic blood pressure, mean blood pressure, pulse pressure, and pulse wave velocity were significantly higher in patients on hemodialysis than in healthy subjects, pulse propagation time was significantly higher in healthy subjects. Although body weight, systolic blood pressure, diastolic blood pressure, mean blood pressure, pulse pressure, and pulse wave velocity were significantly decreased, heart rate and pulse propagation time were significantly increased after ultrafiltration. There was a significant positive correlation between pulse wave velocity and age, body height, waist circumference, systolic blood pressure, diastolic blood pressure, mean blood pressure, pulse pressure, and heart rate.
  
  
  CONCLUSIONS
  Although hemodialysis treatment may chronically worsen aortic mechanical properties, ultrafiltration during hemodialysis may significantly improve aortic pulse wave velocity, which is inversely related to aortic distensibility and pulse propagation time.
authors.affiliation: Department of Internal Medicine, Dr. Lütfi Kırdar Kartal Educational and Research Hospital; İstanbul-Turkey. yildizim76@yahoo.com.
authors.forename: Banu
authors.initials: B
authors.lastname: Şahin Yildiz
authors.forename: Alparslan
authors.initials: A
authors.lastname: Şahin
authors.forename: Nazire
authors.initials: N
authors.lastname: Başkurt Aladağ
authors.forename: Gülgün
authors.initials: G
authors.lastname: Arslan
authors.forename: Hakan
authors.initials: H
authors.lastname: Kaptanoğullari
authors.forename: İbrahim
authors.initials: İ
authors.lastname: Akın
authors.forename: Mustafa
authors.initials: M
authors.lastname: Yildiz
mesh_terms: D000328:Adult; D000367:Age Factors; D001011:Aorta / Q000503:physiopathology*; D001783:Blood Flow Velocity; D001794:Blood Pressure; D049628:Body Size; D016022:Case-Control Studies; D005260:Female; D017583:Hemodiafiltration / Q000295:instrumentation*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D011673:Pulsatile Flow; D014462:Ultrafiltration