title: Long-term efficacy and safety of biodegradable-polymer biolimus-eluting stents: main results of the Basel Stent Kosten-Effektivitäts Trial-PROspective Validation Examination II (BASKET-PROVE II), a randomized, controlled noninferiority 2-year outcome trial.
abstract: BACKGROUND
  Biodegradable-polymer drug-eluting stents (BP-DES) were developed to be as effective as second-generation durable-polymer drug-eluting stents (DP-DES) and as safe >1 year as bare-metal stents (BMS). Thus, very late stent thrombosis (VLST) attributable to durable polymers should no longer appear.
  
  
  RESULTS
  To address these early and late aspects, 2291 patients presenting with acute or stable coronary disease needing stents ≥3.0 mm in diameter between April 2010 and May 2012 were randomly assigned to biolimus-A9-eluting BP-DES, second-generation everolimus-eluting DP-DES, or thin-strut silicon-carbide-coated BMS in 8 European centers. All patients were treated with aspirin and risk-adjusted doses of prasugrel. The primary end point was combined cardiac death, myocardial infarction, and clinically indicated target-vessel revascularization within 2 years. The combined secondary safety end point was a composite of VLST, myocardial infarction, and cardiac death. The cumulative incidence of the primary end point was 7.6% with BP-DES, 6.8% with DP-DES, and 12.7% with BMS. By intention-to-treat BP-DES were noninferior (predefined margin, 3.80%) compared with DP-DES (absolute risk difference, 0.78%; -1.93% to 3.50%; P for noninferiority 0.042; per protocol P=0.09) and superior to BMS (absolute risk difference, -5.16; -8.32 to -2.01; P=0.0011). The 3 stent groups did not differ in the combined safety end point, with no decrease in events >1 year, particularly VLST with BP-DES.
  
  
  CONCLUSIONS
  In large vessel stenting, BP-DES appeared barely noninferior compared with DP-DES and more effective than thin-strut BMS, but without evidence for better safety nor lower VLST rates >1 year. Findings challenge the concept that durable polymers are key in VLST formation.
  
  
  BACKGROUND
  http://www.clinicaltrials.gov. Unique identifier: NCT01166685.
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.). Christoph.kaiser@usb.ch.
authors.forename: Christoph
authors.initials: C
authors.lastname: Kaiser
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Soeren
authors.initials: S
authors.lastname: Galatius
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Raban
authors.initials: R
authors.lastname: Jeger
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Nicole
authors.initials: N
authors.lastname: Gilgen
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Jan
authors.initials: J
authors.lastname: Skov Jensen
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Christoph
authors.initials: C
authors.lastname: Naber
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Hannes
authors.initials: H
authors.lastname: Alber
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Maria
authors.initials: M
authors.lastname: Wanitschek
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Franz
authors.initials: F
authors.lastname: Eberli
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: David J
authors.initials: DJ
authors.lastname: Kurz
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Giovanni
authors.initials: G
authors.lastname: Pedrazzini
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Tiziano
authors.initials: T
authors.lastname: Moccetti
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Hans
authors.initials: H
authors.lastname: Rickli
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Daniel
authors.initials: D
authors.lastname: Weilenmann
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: André
authors.initials: A
authors.lastname: Vuillomenet
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Martin
authors.initials: M
authors.lastname: Steiner
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Stefanie
authors.initials: S
authors.lastname: Von Felten
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Deborah R
authors.initials: DR
authors.lastname: Vogt
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Kim
authors.initials: K
authors.lastname: Wadt Hansen
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Peter
authors.initials: P
authors.lastname: Rickenbacher
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: David
authors.initials: D
authors.lastname: Conen
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Christian
authors.initials: C
authors.lastname: Müller
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Peter
authors.initials: P
authors.lastname: Buser
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Andreas
authors.initials: A
authors.lastname: Hoffmann
authors.affiliation: From the Department of Cardiology, University Hospital, Basel, Switzerland (C.K., R.J., N.G., P.B., A.H., M.P.); Cardiology, Gentofte University Hospital, Copenhagen, Denmark (S.G., J.S.J., K.W.H.); Cardiology, Elisabeth-Krankenhaus, Essen, Germany (C.N.); Cardiology, University Hospital, Innsbruck, Austria (H.A., M.W.); Cardiology, Triemlispital, Zürich, Switzerland (F.E., D.J.K.); Cardiocentro, Lugano, Switzerland (G.P., T.M.); Cardiology, State Hospital, St. Gallen, Switzerland (H.R., D.W.); State Hospital, Aarau, Switzerland (A.V., M.S.); Clinical Trial Unit, University Hospital Basel, Switzerland (S.V.F., D.R.V.); Bruderholzspital, Bruderholz, Switzerland (P.R.); and the Department of Internal Medicine, University Hospital Basel, Switzerland (D.C., C.M.).
authors.forename: Matthias
authors.initials: M
authors.lastname: Pfisterer
mesh_terms: D020341:Absorbable Implants / Q000009:adverse effects; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001241:Aspirin / Q000627:therapeutic use; D003324:Coronary Artery Disease / Q000628:therapy*; D054855:Drug-Eluting Stents / Q000009:adverse effects; D000068338:Everolimus; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008137:Longitudinal Studies; D008297:Male; D008670:Metals; D008875:Middle Aged; D010879:Piperazines / Q000627:therapeutic use; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011108:Polymers / Q000009:adverse effects; D000068799:Prasugrel Hydrochloride; D058921:Purinergic P2Y Receptor Antagonists / Q000627:therapeutic use; D016037:Single-Blind Method; D020123:Sirolimus / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D015607:Stents; D013557:Switzerland; D013876:Thiophenes / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D008670:Metals; D010879:Piperazines; D010975:Platelet Aggregation Inhibitors; D011108:Polymers; D058921:Purinergic P2Y Receptor Antagonists; D013876:Thiophenes; D000068338:Everolimus; D000068799:Prasugrel Hydrochloride; D001241:Aspirin; C518022:umirolimus; D020123:Sirolimus
keywords: antiplatelet drugs; clinical trial; coronary artery disease; coronary thrombosis; drug-coated stents; drug-eluting stents