title: Safety and efficacy of combining microfocused ultrasound with fractional CO2 laser resurfacing for lifting and tightening the face and neck.
abstract: BACKGROUND
  Microfocused ultrasound (MFU) and ablative fractionated laser (AFL) resurfacing techniques have been used separately to noninvasively improve skin laxity and rhytides on the face and neck. Simultaneous combination treatment would be anticipated to provide further improvement but has not previously studied.
  
  
  METHODS
  A retrospective analysis of 100 combination face and neck treatments from 3 centers was performed, including collective treatment protocols, postoperative recovery, side effect profile, and clinical results.
  
  
  RESULTS
  Skin laxity and photodamage (rhytides and texture) showed significant improvement with combination MFU + AFL treatment. Except for increased facial swelling in a small percentage of patients, postoperative recovery and side effects were comparable with those obtained after application of individual treatments.
  
  
  CONCLUSIONS
  Combination MFU-AFL on the face and neck is a safe and effective method for targeting multiple facets of facial and neck skin aging and can be safely performed in a single treatment session.
authors.affiliation: *Division of Oculoplastic and Reconstructive Surgery Service, Department of Ophthalmology and Dermatology, Duke University Eye Center, Durham, North Carolina; †Division of Dermatology, Department of Medicine, University of California, San Diego, California; ‡Goldman, Butterwick, Fitzpatrick, Groff & Fabi, Cosmetic Laser Dermatology, San Diego, California; §Division of Dermatology, Georgetown University Medical Center, Washington, DC; ‖Washington Institute of Dermatologic Laser Surgery, Washington, DC.
authors.forename: Julie A
authors.initials: JA
authors.lastname: Woodward
authors.forename: Sabrina G
authors.initials: SG
authors.lastname: Fabi
authors.forename: Tina
authors.initials: T
authors.lastname: Alster
authors.forename: Betsy
authors.initials: B
authors.lastname: Colón-Acevedo
mesh_terms: D003131:Combined Modality Therapy; D062109:Dermatologic Surgical Procedures; D005145:Face; D057086:High-Intensity Focused Ultrasound Ablation; D006801:Humans; D053685:Laser Therapy; D054020:Lasers, Gas / Q000627:therapeutic use*; D009333:Neck; D012189:Retrospective Studies; D015361:Rhytidoplasty / Q000379:methods; D015595:Skin Aging / Q000528:radiation effects*; D016896:Treatment Outcome