title: Participation in a Social-Support Physical Activity Intervention Modestly Improves Lipoprotein Cholesterol Distribution Among Postpartum Sedentary Hispanic Women.
abstract: BACKGROUND
  The effects of moderate intensity walking on lipoprotein remodeling in postpartum Hispanic women are unknown.
  
  
  METHODS
  Sedentary postpartum Hispanic women (28.2 ± 5.6 y; BMI = 29.3 ± 3.3 kg/m2) participating in a social support physical activity (PA) intervention, were randomly assigned to a 12-month walking program (walkers; n = 22; target 150 min/wk, moderate intensity) or a control group (nonwalkers; n = 22). Fasting lipids and cholesterol distribution within low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particles were measured at baseline (BL), 6 months, and 12 months.
  
  
  RESULTS
  Walkers had an 11% increase and nonwalkers a 7% decrease in HDL cholesterol from 6 to 12 months (P = .0367) without an effect on LDL cholesterol. Whereas nonwalkers had virtually no change in mean LDL particle size, walkers had a borderline reduction in LDL size from BL (268.7 ± 4.1 Å) to 6 months (266.9 ± 4.9 Å), followed by a significant increase in size by 12 months (269.7 ± 4.1 Å; P = .011). The proportion of cholesterol in large LDL particles decreased by 15% from BL to 6 months, but subsequently increased 25% by 12 months among walkers; changes among nonwalkers were smaller and in opposite direction (4% and -3%, respectively; P = .0004).
  
  
  CONCLUSIONS
  Participation in the social-support PA intervention resulted in slightly increased HDL cholesterol concentrations and a modest and beneficial shift toward larger, less atherogenic LDL particles.
authors.affiliation: School of Nutrition and Health Promotion, Arizona State University, Phoenix, AZ.
authors.forename: Sonia
authors.initials: S
authors.lastname: Vega-López
authors.forename: Giselle A P
authors.initials: GA
authors.lastname: Pignotti
authors.forename: Colleen
authors.initials: C
authors.lastname: Keller
authors.forename: Michael
authors.initials: M
authors.lastname: Todd
authors.forename: Barbara
authors.initials: B
authors.lastname: Ainsworth
authors.forename: Allison
authors.initials: A
authors.lastname: Nagle Williams
authors.forename: Kathie
authors.initials: K
authors.lastname: Records
authors.forename: Dean
authors.initials: D
authors.lastname: Coonrod
authors.forename: Paska
authors.initials: P
authors.lastname: Permana
mesh_terms: D061725:Accelerometry; D000293:Adolescent; D000328:Adult; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D049590:Postpartum Period / Q000502:physiology*; D057185:Sedentary Behavior; D012944:Social Support; D016138:Walking / Q000502:physiology*; D015430:Weight Gain / Q000502:physiology; D055815:Young Adult
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008074:Lipoproteins; C030104:lipoprotein cholesterol; D002784:Cholesterol