title: Angiofibrolipoma of the oral cavity.
abstract: We describe an unusual and rare case of a lipoma variant known as angiofibrolipoma. A literature search revealed only a few cases of angiofibrolipoma which were located in different anatomical sites; no case of angiofibrolipoma in the oral cavity has been previously reported. We present and discuss the histopatholological-immunohistological findings and features. Angiofibrolipoma histologically consists of mature adipocytes, blood vessels, and bundles of collagenous connective tissue with low to moderate cellularity. It is not encapsulated, but is histologically distinct from surrounding tissue. Positive immunohistological staining with CD-34 presented a large number of blood vessels of different sizes located between collagen fibers and adipocytes. The treatment of choice for a patient with angiofibrolipoma is surgical excision, which is expected to be curative.
authors.affiliation: Department of Oral Medicine and Oral Pathology, Dental School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors.forename: Apostolos
authors.initials: A
authors.lastname: Epivatianos
authors.forename: Alexandros
authors.initials: A
authors.lastname: Kolokotronis
authors.forename: Apostolos
authors.initials: A
authors.lastname: Matiakis
authors.forename: Athanasios
authors.initials: A
authors.lastname: Poulopoulos
mesh_terms: D017667:Adipocytes / Q000473:pathology; D000328:Adult; D018322:Angiofibroma / Q000175:diagnosis* / Q000473:pathology; D018206:Angiolipoma / Q000175:diagnosis* / Q000473:pathology; D018952:Antigens, CD34 / Q000032:analysis; D002196:Capillaries / Q000473:pathology; D003094:Collagen / Q000032:analysis; D003238:Connective Tissue / Q000473:pathology; D005337:Fibrin / Q000032:analysis; D005887:Gingival Neoplasms / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male
chemical_list: D018952:Antigens, CD34; D005337:Fibrin; D003094:Collagen
keywords: CD-34; histological; immunohistological; lipoma oral angiofibrolipoma