title: Australian Rotavirus Surveillance Program annual report, 2012.
abstract: This report from the Australian Rotavirus Surveillance Program, together with collaborating laboratories Australia-wide, describes the rotavirus genotypes responsible for the hospitalisation of children with acute gastroenteritis during the period 1 January to 31 December 2012. During the survey period, 1,300 faecal samples were referred to the centre for rotavirus G and P genotype analysis, and of these 748 were confirmed as rotavirus positive. A total of 491 specimens were collected from children under 5 years of age, while 257 were from older children and adults. Genotype analysis revealed that G1P[8] was the dominant type in this reporting period, identified in 35% of strains nationally. Genotype G2P[4] was the second most common strain nationally, representing 28% of samples, followed by genotype G12P[8] (23%). This represents the first report where G12P[8] strains are a major cause of disease in this community. Fluctuations in genotype distribution were also observed based on the vaccine type in use. Genotype G2P[4] was more common in states and territories using Rotarix while G1P[8] was more common in states using RotaTeq. This survey of rotavirus strains circulating in 2012 highlights the continued fluctuations in rotavirus genotypes, with an annual change in dominant genotypes as well as emergence of a previously rare genotype, suggesting a dynamic wild-type population.
authors.affiliation: Senior Research Fellow, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria.
authors.forename: Carl D
authors.initials: CD
authors.lastname: Kirkwood
authors.affiliation: Research Assistant, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria.
authors.forename: Susie
authors.initials: S
authors.lastname: Roczo-Farkas
authors.affiliation: Senior Principal Research Fellow, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria.
authors.forename: Ruth F
authors.initials: RF
authors.lastname: Bishop
authors.affiliation: Senior Principal Research Fellow, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria.
authors.forename: Graeme L
authors.initials: GL
authors.lastname: Barnes
mesh_terms: D017677:Age Distribution; D000847:Annual Reports as Topic; D001315:Australia / Q000453:epidemiology; D002675:Child, Preschool; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology / Q000266:history / Q000821:virology; D005838:Genotype; D049674:History, 21st Century; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011159:Population Surveillance; D012401:Rotavirus / Q000145:classification* / Q000235:genetics*; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000266:history / Q000821:virology*