title: A comparison of impulsivity, depressive symptoms, lifetime stress and sensation seeking in healthy controls versus participants with cocaine or methamphetamine use disorders.
abstract: Previous research has focused on developing theories of addiction that may explain behavior in cocaine- and methamphetamine-dependent individuals. The primary goal of this report was to compare and contrast the prevalence of self-reported measures of impulsivity, depression, lifetime stress and sensation-seeking in healthy controls versus individuals with cocaine or methamphetamine use disorders. Twenty-nine individuals with cocaine use disorders and 31 individuals with methamphetamine use disorders were matched with 31 healthy control participants on several demographic variables. All participants were administered behavioral questionnaires including the Barrett Impulsiveness Scale (assessing impulsivity), Beck Depression Inventory II (assessing depression), Life Stressor Checklist-Revised (assessing lifetime stress) and the Impulsive Sensation Seeking Scale (assessing sensation-seeking). When compared to healthy controls, individuals with cocaine and methamphetamine use disorders had significantly higher levels of impulsivity and sensation-seeking. In addition, when compared to healthy controls, individuals with cocaine use disorders had significantly higher Beck Depression Inventory II scores, while individuals with methamphetamine use disorders had significantly higher Life Stressor Checklist-Revised scores. The results revealed that there were significantly higher levels of impulsivity, depression and sensation-seeking in cocaine users and significantly higher impulsivity, lifetime stress and sensation-seeking in methamphetamine users when compared to healthy controls.
authors.affiliation: Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA Michael E DeBakey VA Medical Center, Houston, TX, USA.
authors.forename: James J
authors.initials: JJ
authors.lastname: Mahoney
authors.affiliation: Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA Michael E DeBakey VA Medical Center, Houston, TX, USA.
authors.forename: Daisy G Y
authors.initials: DG
authors.lastname: Thompson-Lake
authors.affiliation: Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA Michael E DeBakey VA Medical Center, Houston, TX, USA.
authors.forename: Kimberly
authors.initials: K
authors.lastname: Cooper
authors.affiliation: Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA Michael E DeBakey VA Medical Center, Houston, TX, USA.
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Verrico
authors.affiliation: Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA Michael E DeBakey VA Medical Center, Houston, TX, USA.
authors.forename: Thomas F
authors.initials: TF
authors.lastname: Newton
authors.affiliation: Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA Michael E DeBakey VA Medical Center, Houston, TX, USA rg12@bcm.edu.
authors.forename: Richard
authors.initials: R
authors.lastname: De La Garza
mesh_terms: D000328:Adult; D019969:Amphetamine-Related Disorders / Q000523:psychology*; D016739:Behavior, Addictive / Q000523:psychology; D019970:Cocaine-Related Disorders / Q000523:psychology*; D003863:Depression / Q000523:psychology*; D055030:Drug Users / Q000523:psychology*; D005260:Female; D006801:Humans; D007175:Impulsive Behavior / Q000502:physiology*; D008297:Male; D008694:Methamphetamine; D057566:Self Report; D013315:Stress, Psychological / Q000523:psychology*; D011795:Surveys and Questionnaires
chemical_list: D008694:Methamphetamine
keywords: Stress; cocaine; depression; impulsivity; methamphetamine; sensation seeking