title: Is laparoscopic sleeve gastrectomy a lower risk bariatric procedure compared with laparoscopic Roux-en-Y gastric bypass? A meta-analysis.
abstract: BACKGROUND
  Laparoscopic Roux-en-Y gastric bypass (LRYGB) is the current "gold standard" bariatric procedure in the United States. Laparoscopic sleeve gastrectomy (LSG) has recently become a commonly performed procedure for many reasons, including patients' perception that LSG has less complexity and invasiveness, and lower risk. Our objective was to review the literature and compare the leak rates, morbidity, and mortality for LRYGB versus LSG.
  
  
  METHODS
  Publications from 2002 to 2012 with n greater than or equal to 25 and postoperative leak rate reported were included. Statistical analysis included chi-square according to patient number.
  
  
  RESULTS
  Twenty-eight (10,906 patients) LRYGB and 33 (4,816 patients) LSG articles were evaluated. Leak rates after LRYGB versus LSG were 1.9% (n = 206) versus 2.3% (n = 110), respectively (P = .077). Mortality rates were .4% (27/7,117) for LRYGB and .2% (7/3,594) for LSG (P = .110). Timing from surgery to leak ranged from 1 to 12 days for LRYGB versus 1 to 35 days for LSG.
  
  
  CONCLUSIONS
  Leak and mortality rates after LRYGB and LSG were comparable. The appropriate procedure should be tailored based on patient factors, comorbidities, patient and surgeon comfort level, surgeon experience, and institutional outcomes.
authors.affiliation: Department of Medical Education, Gundersen Health System, 1900 South Avenue, La Crosse, WI 54601, USA.
authors.forename: Jonathan D
authors.initials: JD
authors.lastname: Zellmer
authors.affiliation: Department of Medical Research, Gundersen Medical Foundation, Gundersen Health System, 1900 South Avenue, La Crosse, WI 54601, USA.
authors.forename: Michelle A
authors.initials: MA
authors.lastname: Mathiason
authors.affiliation: Department of Medical Research, Gundersen Medical Foundation, Gundersen Health System, 1900 South Avenue, La Crosse, WI 54601, USA.
authors.forename: Kara J
authors.initials: KJ
authors.lastname: Kallies
authors.affiliation: Department of General and Vascular Surgery, Gundersen Health System, 1900 South Avenue, La Crosse, WI 54601, USA. Electronic address: snkothar@gundersenhealth.org.
authors.forename: Shanu N
authors.initials: SN
authors.lastname: Kothari
mesh_terms: D057868:Anastomotic Leak / Q000453:epidemiology; D005743:Gastrectomy / Q000379:methods*; D015390:Gastric Bypass / Q000379:methods*; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D009767:Obesity, Morbid / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology; D012306:Risk
keywords: Anastomotic leak; Bariatric surgery; Bleeding; Laparoscopic sleeve gastrectomy; Postoperative complications; Roux-en-Y gastric bypass