title: Retinal ganglion cell analysis in multiple evanescent white dot syndrome.
abstract: BACKGROUND
  Multiple evanescent white dot syndrome (MEWDS) is an acute and usually unilateral retinopathy that occurs predominantly in young adults. This report presents the outcomes of ganglion cell analysis (GCA) in MEWDS.
  
  
  METHODS
  A 41-year-old woman was diagnosed as MEWDS in right eye. At her initial visit, the deviation map of the ganglion cell analysis showed there was a decrease of the ganglion cell layer (GCL) + inner plexiform layer (IPL) thickness in both eyes, even though her left eye was not affected. A 29-year-old woman was also diagnosed as MEWDS in right eye. Although the deviation map of ganglion cell analysis showed there was a decrease of the GCL + IPL thickness in both eyes at her initial visit, her right eye was not affected.
  
  
  CONCLUSIONS
  GCA indicated there was a decrease (<1% of the distribution of normals) of the ganglion cell layer + inner plexiform layer thickness in both the affected and fellow eyes in 7 of 9 patients diagnosed as MEWDS in our hospital. Although the lesions responsible for MEWDS are thought to disrupt the photoreceptor outer segments, we observed changes in the inner retina in both the affected and fellow eye of MEWDS patients.
authors.affiliation: Department of Ophthalmology, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, Maebashi, Gunma 371-8511, Japan. akiyamah47@gunma-u.ac.jp.
authors.forename: Hideo
authors.initials: H
authors.lastname: Akiyama
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Itakura
authors.forename: Danjie
authors.initials: D
authors.lastname: Li
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Kashima
authors.forename: Keisuke
authors.initials: K
authors.lastname: Nitta
authors.forename: Yukitoshi
authors.initials: Y
authors.lastname: Shimoda
authors.forename: Ryo
authors.initials: R
authors.lastname: Mukai
authors.forename: Shoji
authors.initials: S
authors.lastname: Kishi
mesh_terms: D000328:Adult; D004396:Coloring Agents; D005260:Female; D006801:Humans; D007208:Indocyanine Green; D012164:Retinal Diseases / Q000175:diagnosis*; D012165:Retinal Ganglion Cells / Q000473:pathology*; D055211:Retinal Photoreceptor Cell Inner Segment / Q000473:pathology; D055214:Retinal Photoreceptor Cell Outer Segment / Q000473:pathology; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D014794:Visual Fields / Q000502:physiology
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green