title: Genetics of bovine respiratory disease in cattle: can breeding programs reduce the problem?
abstract: Genetics is responsible for approximately half the observed change in performance internationally in well-structured cattle breeding programs. Almost all, if not all, individual characteristics, including animal health, have a genetic basis. Once genetic variation exists then breeding for improvement is possible. Although the heritability of most health traits is low to moderate, considerable exploitable genetic variation does exist. From the limited studies undertaken, and mostly from limited datasets, the direct heritability of susceptibility to BRD varied from 0.07 to 0.22 and the maternal heritability (where estimated) varied from 0.05 to 0.07. Nonetheless, considerable genetic variation clearly exists; the genetic standard deviation for the direct component (binary trait), although differing across populations, varied from 0.08 to 0.20 while the genetic standard deviation for the maternal component varied from 0.04 to 0.07. Little is known about the genetic correlation between genetic predisposition to BRD and animal performance; the estimation of these correlations should be prioritized. (Long-term) Breeding strategies to reduce the incidence of BRD in cattle should be incorporated into national BRD eradication or control strategies.
authors.affiliation: Animal and Bioscience Research Department,Animal and Grassland Research and Innovation Centre,Teagasc,Moorepark,Fermoy,Co. Cork,Ireland.
authors.forename: Donagh P
authors.initials: DP
authors.lastname: Berry
mesh_terms: D000818:Animals; D048090:Bovine Respiratory Disease Complex / Q000453:epidemiology / Q000235:genetics* / Q000517:prevention & control*; D001947:Breeding; D002417:Cattle; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation; D005838:Genotype; D015994:Incidence; D010641:Phenotype; D015995:Prevalence