title: Chiari malformation and central sleep apnea syndrome: efficacy of treatment with adaptive servo-ventilation.
abstract: The Chiari malformation type I (CM-I) has been associated with sleep-disordered breathing, especially central sleep apnea syndrome. We report the case of a 44-year-old female with CM-I who was referred to our sleep laboratory for suspected sleep apnea. The patient had undergone decompressive surgery 3 years prior. An arterial blood gas analysis showed hypercapnia. Polysomnography showed a respiratory disturbance index of 108 events/h, and all were central apnea events. Treatment with adaptive servo-ventilation was initiated, and central apnea was resolved. This report demonstrates the efficacy of servo-ventilation in the treatment of central sleep apnea syndrome associated with alveolar hypoventilation in a CM-I patient with a history of decompressive surgery.
authors.affiliation: Tondela-Viseu Hospital Center, Viseu, Portugal.
authors.forename: Jorge Marques do
authors.initials: JM
authors.lastname: Vale
authors.affiliation: Tondela-Viseu Hospital Center, Viseu, Portugal.
authors.forename: Eloísa
authors.initials: E
authors.lastname: Silva
authors.affiliation: Tondela-Viseu Hospital Center, Viseu, Portugal.
authors.forename: Isabel Gil
authors.initials: IG
authors.lastname: Pereira
authors.affiliation: Tondela-Viseu Hospital Center, Viseu, Portugal.
authors.forename: Catarina
authors.initials: C
authors.lastname: Marques
authors.affiliation: Tondela-Viseu Hospital Center, Viseu, Portugal.
authors.forename: Amparo
authors.initials: A
authors.lastname: Sanchez-Serrano
authors.affiliation: Tondela-Viseu Hospital Center, Viseu, Portugal.
authors.forename: António Simões
authors.initials: AS
authors.lastname: Torres
mesh_terms: D000328:Adult; D001139:Arnold-Chiari Malformation / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D017286:Polysomnography; D012121:Respiration, Artificial / Q000379:methods*; D020182:Sleep Apnea, Central / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*