title: Correlation between the ganglion cell complex and functional measures in glaucoma patients and suspects.
abstract: The purpose of the study was to correlate the Fourier-domain OCT ganglion cell complex (GCC) parameters with automated perimetry (AP) functional measures of the optic nerve. This retrospective study included patients who had previously undergone examination with the RTVue-100 OCT and AP, SITA strategy. The parameters of GCC (average, superior, inferior, S-I [superior inferior difference], S-I SD [standard deviation of S-I], GLV [global loss volume] and FLV [focal loss volume]) were correlated with the mean deviation (MD) and pattern standard deviation (PSD) values of AP using linear and logarithmic regression analysis. All correlations between GCC and automated perimetry parameters were strong (r > 0.60), except that for SI and MD (r = -0.05); SI and PSD (r = 0.09); SI-DS and MD (r = -0.06); and SI-SD and PSD (r = 0.08). In summary, GCC derived structural measures showed good correlation with functional parameters from AP.
authors.affiliation: Department of Ophthalmology, Irmandade da Santa Casa de Misericordia de Sao Paulo, Santa Casa de Sao Paulo School of Medical Sciences, Rua Sao Mauro, 292, São Paulo, 02526-050, Brazil.
authors.forename: Ivan C
authors.initials: IC
authors.lastname: Teixeira
authors.affiliation: Department of Ophthalmology, Irmandade da Santa Casa de Misericordia de Sao Paulo, Santa Casa de Sao Paulo School of Medical Sciences, Rua Sao Mauro, 292, São Paulo, 02526-050, Brazil.
authors.forename: Erica
authors.initials: E
authors.lastname: Bresciani-Battilana
authors.affiliation: Department of Ophthalmology, Irmandade da Santa Casa de Misericordia de Sao Paulo, Santa Casa de Sao Paulo School of Medical Sciences, Rua Sao Mauro, 292, São Paulo, 02526-050, Brazil.
authors.forename: Diego T Q
authors.initials: DT
authors.lastname: Barbosa
authors.affiliation: Department of Ophthalmology, Irmandade da Santa Casa de Misericordia de Sao Paulo, Santa Casa de Sao Paulo School of Medical Sciences, Rua Sao Mauro, 292, São Paulo, 02526-050, Brazil.
authors.forename: Cristiano
authors.initials: C
authors.lastname: Caixeta-Umbelino
authors.affiliation: Department of Ophthalmology, Irmandade da Santa Casa de Misericordia de Sao Paulo, Santa Casa de Sao Paulo School of Medical Sciences, Rua Sao Mauro, 292, São Paulo, 02526-050, Brazil.
authors.forename: Maurício D
authors.initials: MD
authors.lastname: Paolera
authors.affiliation: Department of Ophthalmology, Irmandade da Santa Casa de Misericordia de Sao Paulo, Santa Casa de Sao Paulo School of Medical Sciences, Rua Sao Mauro, 292, São Paulo, 02526-050, Brazil. nirokasahara@hotmail.com.
authors.forename: Niro
authors.initials: N
authors.lastname: Kasahara
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology*; D012372:ROC Curve; D012165:Retinal Ganglion Cells / Q000473:pathology*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods*; D014065:Tonometry, Ocular; D058609:Visual Field Tests; D014794:Visual Fields
keywords: Ganglion cell complex; Glaucoma; Perimetry; Visual fields