title: A case report of primary cutaneous histoplasmosis requiring deep tissue sampling for diagnosis.
abstract: This is a case of primary cutaneous histoplasmosis, without any systemic involvement, that occurred without a history of trauma. Due to its rarity and varied clinical presentation, there is much difficulty in diagnosis of this disease entitiy, especially in differentiating it from pyoderma gangreosum. This patient required deep tissue sampling and a DNA probe for Histoplasma to establish a time-sensitive diagnosis as multiple superficial biopsies are nondiagnositic.
authors.affiliation: University of Missouri-Kansas City School of Medicine.
authors.forename: Ramya
authors.initials: R
authors.lastname: Kollipara
authors.forename: Amneet
authors.initials: A
authors.lastname: Hans
authors.forename: John
authors.initials: J
authors.lastname: Hall
authors.forename: Ken
authors.initials: K
authors.lastname: Watson
mesh_terms: D000273:Adipose Tissue / Q000473:pathology; D000328:Adult; D001706:Biopsy / Q000379:methods; D004271:DNA, Fungal / Q000032:analysis*; D003881:Dermatomycoses / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology*; D006658:Histoplasma / Q000235:genetics / Q000302:isolation & purification; D006660:Histoplasmosis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D008297:Male; D012867:Skin / Q000473:pathology; D013848:Thigh
chemical_list: D004271:DNA, Fungal