title: Gestrinone combined with ultrasound-guided aspiration and ethanol injection for treatment of chocolate cyst of ovary.
abstract: OBJECTIVE
  The aim of this study was to determine clinical performance of gestrinone combined with ultrasound-guided aspiration and ethanol injection in treating chocolate cyst of ovary.
  
  
  METHODS
  Sixty-eight patients enrolled in this study were randomly divided into two groups: control group and combination treatment group. In the control group, 34 patients were treated with ultrasound-guided aspiration and ethanol injection. In the combination treatment group, 34 patients received gestrinone p.o. following ultrasound-guided aspiration and ethanol injection.
  
  
  RESULTS
  The recurrence rate of chocolate cyst was 10-fold lower in the combination treatment group (2.94%, 1/34) than in the control group (29.4%, 10/34) at 12 months. The effective rate for reduction of chocolate cyst was significantly higher in the combination treatment group (94.12%, 32/34) than in the control group (64.71%, 22/34) (P = 0.009).
  
  
  CONCLUSIONS
  Gestrinone combined with ultrasound-guided aspiration and ethanol injection therapy is an effective treatment for ovarian chocolate cyst with low recurrence rate.
authors.affiliation: Department of Ultrasound, The Affiliated Yixing People's Hospital of Jiangsu University, Yixing, China.
authors.forename: Xiaoyun
authors.initials: X
authors.lastname: Wu
authors.forename: Yun
authors.initials: Y
authors.lastname: Xu
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D000431:Ethanol / Q000627:therapeutic use*; D005260:Female; D005867:Gestrinone / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D010048:Ovarian Cysts / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D019152:Paracentesis; D011372:Progestins / Q000627:therapeutic use*; D012008:Recurrence; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional; D055815:Young Adult
chemical_list: D011372:Progestins; D005867:Gestrinone; D000431:Ethanol
keywords: chocolate cyst of ovary; gestrinone; ultrasound-guided aspiration and ethanol injection therapy