title: Traumatic bone cyst of the mandible in Langer-Giedion syndrome: a case report.
abstract: BACKGROUND
  Langer-Giedion syndrome (trichorhinophalangeal syndrome type II) is an extremely rare disorder characterized by dysmorphic facial features, multiple exostoses, mental retardation and digit deformities. We report the first case of any maxillofacial pathology in such a syndromic patient.
  
  
  METHODS
  A 22-year-old Indian woman with mild intellectual disability presented with malaligned teeth. Routine radiographic screening demonstrated a large multilocular lesion in her right mandible. She had peculiar features such as short stature, short limbs, brachydactyly, and dysmorphic facial characters, which prompted us to evaluate her further. After findings of multiple bony exostoses she was diagnosed with Langer-Giedion syndrome. On surgical exploration of her right mandibular lesion an empty cavity was found suggestive of traumatic bone cyst. The lesion healed completely after 1 year without loss of vitality of any teeth.
  
  
  CONCLUSIONS
  Although diagnosis and management of any maxillofacial pathology can be challenging in syndromic patients, our report suggests a possible correlation between traumatic bone cyst and Langer-Giedion syndrome. Clinicians should routinely screen these patients for any undetected maxillofacial pathology. In future cases of this syndrome, one should consider the possibility of traumatic bone cyst which may not require aggressive surgical management.
authors.forename: Shakil Ahmed
authors.initials: SA
authors.lastname: Nagori
authors.forename: Anson
authors.initials: A
authors.lastname: Jose
authors.forename: Bhaskar
authors.initials: B
authors.lastname: Agarwal
authors.forename: Krushna
authors.initials: K
authors.lastname: Bhatt
authors.forename: Ongkila
authors.initials: O
authors.lastname: Bhutia
authors.affiliation: Department of Oral and Maxillofacial Surgery, CDER, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India. ajoyroy@hotmail.com.
authors.forename: Ajoy
authors.initials: A
authors.lastname: Roychoudhury
mesh_terms: D001845:Bone Cysts / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D015826:Langer-Giedion Syndrome / Q000150:complications*; D008334:Mandible / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D011862:Radiography, Panoramic; D014057:Tomography, X-Ray Computed; D055815:Young Adult