title: Antioxidant and antifungal activity of different extracts obtained from aerial parts of Inula crithmoides L.
abstract: The total phenolic content, antioxidant and antifungal activities of three Inula crithmoides extracts (n-hexane, methylene chloride and MeOH) were investigated. The methanolic extract showed the highest total phenolic content. In the DPPH assay, the methanolic and hexane extracts exhibited the highest DPPH-radical scavenging activity; in the 5-lipoxygenase assay, the hexane extract showed greater inhibitory effect with an IC50 similar to that of Trolox and ascorbic acid. The antifungal activity of the methanolic extract revealed a higher activity against Phytophtora cryptogea and Alternaria solani.
authors.affiliation: a Dipartimento di Scienze della Terra , della Vita e dell'Ambiente - Università di Urbino "Carlo Bo" , Via Bramante 28, 61029 Urbino (PU) , Italy.
authors.forename: Anahi
authors.initials: A
authors.lastname: Bucchini
authors.forename: Donata
authors.initials: D
authors.lastname: Ricci
authors.forename: Federica
authors.initials: F
authors.lastname: Messina
authors.forename: Maria Carla
authors.initials: MC
authors.lastname: Marcotullio
authors.forename: Massimo
authors.initials: M
authors.lastname: Curini
authors.forename: Laura
authors.initials: L
authors.lastname: Giamperi
mesh_terms: D000528:Alternaria / Q000187:drug effects; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D000935:Antifungal Agents / Q000494:pharmacology*; D016166:Free Radical Scavengers / Q000494:pharmacology*; D038143:Inula / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry*; D010838:Phytophthora / Q000187:drug effects; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000893:Anti-Inflammatory Agents; D000935:Antifungal Agents; D016166:Free Radical Scavengers; D010636:Phenols; D010936:Plant Extracts
keywords: Inula crithmoides; antifungal activity; antioxidant activity; phenolics