title: Outcomes in liver transplantation: does sex matter?
abstract: A growing literature has highlighted important differences in transplant-related outcomes between men and women. In the United States there are fewer women than men on the liver transplant waitlist and women are two times less likely to receive a deceased or living-related liver transplant. Sex-based differences exist not only in waitlist but also in post-transplant outcomes, particularly in some specific liver diseases, such as hepatitis C. In the era of individualized medicine, recognition of these differences in the approach to pre and post-liver transplant care may impact short and long-term outcomes.
authors.affiliation: Division of Gastroenterology and Hepatology, University of California, San Francisco, 513 Parnassus Avenue, S-357, San Francisco, CA 94143, USA. Electronic address: Monika.Sarkar@ucsf.edu.
authors.forename: Monika
authors.initials: M
authors.lastname: Sarkar
authors.affiliation: Division of Gastroenterology and Hepatology, Mayo Clinic and Foundation, 200 First St, Rochester, MN 55905, USA.
authors.forename: Kymberly D
authors.initials: KD
authors.lastname: Watt
authors.affiliation: Division of Gastroenterology and Hepatology, University of California, San Francisco, 513 Parnassus Avenue, S-357, San Francisco, CA 94143, USA.
authors.forename: Norah
authors.initials: N
authors.lastname: Terrault
authors.affiliation: Hepatology and Liver Transplantation Unit, La Fe Hospital and Ciberehd, Universidad Valencia, C/Bulevar Sur sn (Torre F-5) 46026 Valencia, Spain.
authors.forename: Marina
authors.initials: M
authors.lastname: Berenguer
mesh_terms: D058625:End Stage Liver Disease / Q000601:surgery*; D005260:Female; D006085:Graft Survival; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects / Q000379:methods / Q000706:statistics & numerical data; D008297:Male; D017063:Outcome Assessment, Health Care; D059035:Perioperative Period; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology; D012737:Sex Factors; D009927:Tissue and Organ Procurement / Q000379:methods; D014850:Waiting Lists
keywords: Hepatitis C virus; Liver allocation; Liver transplantation; MELD score; Quality of life; Sex; Waitlist outcome; Women’s health