title: [Pulmonary alveolar proteinosis - a case report].
abstract: Pulmonary alveolar proteinosis (PAP) is a rare lung disease of unknown origin, where an amorphous lipoprotein material accumulates in the alveoli of the lungs. We describe a young male with a four month history of progressive dyspnea, low grade fever, hypoxemia and weight loss. Chest X-ray showed diffuse interstitial and alveolar infiltrates in both lungs. The diagnosis of PAP was confirmed with trans-bronchial lung biopsy. Because of a deteriorating clinical course a whole lung lavage was performed. Under general anesthesia, both lungs were lavaged with warm saline in two different sessions with good results. Two years later the patient is almost free of symptoms and lung function has markedly improved.
authors.forename: Ragnheidur M
authors.initials: RM
authors.lastname: Johannesdottir
authors.forename: Steinn
authors.initials: S
authors.lastname: Jonsson
authors.forename: Felix
authors.initials: F
authors.lastname: Valsson
authors.forename: Hronn
authors.initials: H
authors.lastname: Hardardottir
authors.forename: Olof R
authors.initials: OR
authors.lastname: Amundadottir
authors.forename: Eythor
authors.initials: E
authors.lastname: Bjornsson
authors.forename: Sigfus
authors.initials: S
authors.lastname: Nikulasson
authors.forename: Tomas
authors.initials: T
authors.lastname: Gudbjartsson
mesh_terms: D001706:Biopsy; D018893:Bronchoalveolar Lavage / Q000379:methods; D006801:Humans; D008297:Male; D011649:Pulmonary Alveolar Proteinosis / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D020127:Recovery of Function; D012965:Sodium Chloride / Q000008:administration & dosage; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D012965:Sodium Chloride