title: [Surgical management of patients with pathological deformities of carotid arteries].
abstract: Surgical management of pathological deformities of the internal carotid arteries, a cause of chronic brain ischemia, is discussed. This pathology is very common and is found in 25% of all individuals who underwent preventive medical examination according to the ultrasonography data. Most deformities do not pose any threat to patients, while some of them may cause ischemic stroke and chronic brain ischemia. The study included 165 patients with the known follow-up history who had been operated on at the N.N. Burdenko Neurosurgical Institute since 2001. A total of 196 reconstructive interventions of carotid arteries were analyzed. The indications for surgical management of pathological deformities based on clinical symptoms and identification of the signs of vascular wall dysplasia are thoroughly discussed. The local and cerebral hemodynamics during pre- and postoperative period are analyzed. The results of pathomorphological examination of the resected fragments of the deformed arteries are presented; they show that the changes are identical to those in patients with fibromuscular dysplasia. The follow-up history of the patients was recorded; it showed a sustained regression of transitory ischemic strokes and cerebral symptoms in most cases (69%). For proper indications for surgical management, reconstructive surgical interventions are a reliable and effective method for treating chronic brain ischemia and preventing recurrent ischemic strokes in patients with deformities of carotid arteries.
authors.forename: D Yu
authors.initials: DY
authors.lastname: Usachev
authors.forename: V A
authors.initials: VA
authors.lastname: Lukshin
authors.forename: A D
authors.initials: AD
authors.lastname: Sosnin
authors.forename: L V
authors.initials: LV
authors.lastname: Shishkina
authors.forename: A V
authors.initials: AV
authors.lastname: Shimgel'skii
authors.forename: I A
authors.initials: IA
authors.lastname: Nagorskaya
authors.forename: V V
authors.initials: VV
authors.lastname: Vasil'chenko
authors.forename: A Yu
authors.initials: AY
authors.lastname: Belyaev
authors.forename: A D
authors.initials: AD
authors.lastname: Akhmedov
authors.forename: E V
authors.initials: EV
authors.lastname: Batishcheva
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000150:complications; D002343:Carotid Artery, Internal / Q000473:pathology / Q000601:surgery*; D016893:Carotid Stenosis / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D002648:Child; D005260:Female; D005352:Fibromuscular Dysplasia / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged