title: Ultrahigh-speed swept-source OCT angiography in exudative AMD.
abstract: OBJECTIVE
  To investigate the potential of ultrahigh-speed swept-source optical coherence tomography angiography (OCTA) to visualize retinal and choroidal vascular changes in patients with exudative age-related macular degeneration (AMD).
  
  
  METHODS
  Observational, prospective cross-sectional study. An ultrahigh-speed swept-source prototype was used to perform OCTA of the retinal and choriocapillaris microvasculature in 63 eyes of 32 healthy controls and 19 eyes of 15 patients with exudative AMD.
  
  
  METHODS
  qualitative comparison of the retinal and choriocapillaris microvasculature in the two groups.
  
  
  RESULTS
  Choroidal neovascularization (CNV) was clearly visualized in 16 of the 19 eyes with exudative AMD, located above regions of severe choriocapillaris alteration. In 14 of these eyes, the CNV lesions were surrounded by regions of choriocapillaris alteration.
  
  
  CONCLUSIONS
  OCTA may offer noninvasive monitoring of the retinal and choriocapillaris microvasculature in patients with CNV, which may assist in diagnosis and monitoring.
authors.forename: Eric
authors.initials: E
authors.lastname: Moult
authors.forename: WooJhon
authors.initials: W
authors.lastname: Choi
authors.forename: Nadia K
authors.initials: NK
authors.lastname: Waheed
authors.forename: Mehreen
authors.initials: M
authors.lastname: Adhi
authors.forename: ByungKun
authors.initials: B
authors.lastname: Lee
authors.forename: Chen D
authors.initials: CD
authors.lastname: Lu
authors.forename: Vijaysekhar
authors.initials: V
authors.lastname: Jayaraman
authors.forename: Benjamin
authors.initials: B
authors.lastname: Potsaid
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Rosenfeld
authors.forename: Jay S
authors.initials: JS
authors.lastname: Duker
authors.forename: James G
authors.initials: JG
authors.lastname: Fujimoto
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D002829:Choroid / Q000098:blood supply*; D020256:Choroidal Neovascularization / Q000175:diagnosis*; D019842:Ciliary Arteries / Q000000981:diagnostic imaging / Q000473:pathology; D003430:Cross-Sectional Studies; D005122:Exudates and Transudates; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012171:Retinal Vessels / Q000000981:diagnostic imaging / Q000473:pathology; D041623:Tomography, Optical Coherence; D057135:Wet Macular Degeneration / Q000175:diagnosis*; D055815:Young Adult