title: Platelets as potential link between diabetes and Alzheimer's disease.
abstract: Diabetes is a well-known risk factor for Alzheimer`s disease (AD) development in the elderly. The molecular link between diabetes and AD is still not completely understood. Recent evidence suggests that platelet activation observed in diabetes may contribute to AD development. The present review summarizes the common molecular mechanisms involved in the pathophysiology of diabetes and AD and suggests novel therapeutic targets for prevention of the onset or slowing the progression of this disease.
authors.forename: Voahanginirina
authors.initials: V
authors.lastname: Randriamboavonjy
authors.forename: Kateryna
authors.initials: K
authors.lastname: Sopova
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Stellos
authors.affiliation: Department of Psychiatry and Psychotherapy, University Hospital of Tubingen, Calwer Street 14, 72076 Tubingen, Germany. christoph.laske@med.uni-tuebingen.de.
authors.forename: Christoph
authors.initials: C
authors.lastname: Laske
mesh_terms: D000544:Alzheimer Disease / Q000188:drug therapy / Q000378:metabolism*; D000818:Animals; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000378:metabolism*; D006801:Humans