title: [Long-term disease-free survival by S-1 therapy in a case of gastric cancer with peritoneal dissemination].
abstract: The patient was a 77-year-old woman who underwent gastrectomy for gastric cancer. Since the patient had positive peritoneal washing cytology and positive peritoneal dissemination, she was started on oral S-1 therapy post-surgery for 4 weeks, followed by a 2-week rest period. During the first course of therapy, her white blood cell count decreased; therefore, the regimen was changed to a 1-week administration, followed by a 1-week rest period. No subsequent adverse events were noted. The patient has experienced no relapse in the four years she has been followed up after surgery in our outpatient clinic. We report our experience with an elderly patient for whom S-1 monotherapy was effective in the treatment of gastric cancer with peritoneal dissemination.
authors.affiliation: Dept. of Surgery, Division of Surgical Oncology, Faculty of Medicine, Tottori University.
authors.forename: Manabu
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Osaki
authors.forename: Hirohiko
authors.initials: H
authors.lastname: Kuroda
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nagai
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Watanabe
authors.forename: Sadamu
authors.initials: S
authors.lastname: Takahashi
authors.forename: Yasuro
authors.initials: Y
authors.lastname: Kurisu
authors.forename: Masahide
authors.initials: M
authors.lastname: Ikeguchi
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D004338:Drug Combinations; D005260:Female; D005743:Gastrectomy; D006801:Humans; D010094:Oxonic Acid / Q000627:therapeutic use*; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000556:secondary; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid