title: Pragmatic randomized controlled trial of a structured allergy intervention for adults with asthma and rhinitis in general practice.
abstract: BACKGROUND
  It is widely believed that in patients with allergic rhinitis and asthma, avoidance of specific triggers can help improve symptom control and reduce need for medication. Whilst most patients with asthma or rhinitis are sensitized to airborne allergens, primary care diagnostic and management decisions are often made without either obtaining a detailed history of the patient's allergic triggers or performing skin prick tests. Thus, management decisions are empirical and allergen avoidance advice is either not given or, if given, not tailored to the patient's sensitivities.
  
  
  METHODS
  To ascertain whether allergy assessment and tailored advice in general practice for patients with asthma and rhinitis enhance well-being, we conducted a pragmatic, open, randomized controlled trial of allergy intervention (structured allergy history and skin prick testing and appropriate advice on allergy avoidance) versus usual care in adult patients with a working diagnosis of asthma and/or rhino-conjunctivitis. Outcomes were assessed after 12 months by an observer who was blinded to allocation. The main outcome measures were asthma and rhinitis symptoms, disease-specific health-related quality of life, generic quality of life and lung function.
  
  
  RESULTS
  There were no significant differences in baseline demographics or disease characteristics between patients assigned to immediate or delayed skin prick testing. No significant differences were observed between groups for any measures of symptoms, quality of life or lung function at 12 months (all P > 0.05).
  
  
  CONCLUSIONS
  Amongst adults with known asthma and/or rhinitis in primary care, taking a structured allergy history with skin prick tests and giving tailored advice on allergy avoidance made no difference to their symptoms, quality of life or lung function as measured twelve months later.
authors.affiliation: Division of Primary Care and Public Health, Brighton and Sussex Medical School, Brighton, UK.
authors.forename: H
authors.initials: H
authors.lastname: Smith
authors.forename: D
authors.initials: D
authors.lastname: Horney
authors.forename: S
authors.initials: S
authors.lastname: Goubet
authors.forename: C
authors.initials: C
authors.lastname: Jones
authors.forename: A
authors.initials: A
authors.lastname: Raza
authors.forename: P
authors.initials: P
authors.lastname: White
authors.forename: A
authors.initials: A
authors.lastname: Frew
mesh_terms: D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control; D005260:Female; D005500:Follow-Up Studies; D058006:General Practice; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D015995:Prevalence; D011320:Primary Health Care; D011788:Quality of Life; D012129:Respiratory Function Tests; D065631:Rhinitis, Allergic / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control; D012307:Risk Factors; D057566:Self Report; D012882:Skin Tests; D011795:Surveys and Questionnaires; D055815:Young Adult
keywords: adult; allergy assessment asthma; rhinitis; skin prick testing