title: A comparison of mandibular and maxillary alveolar osteogenesis over six weeks: a radiological examination.
abstract: BACKGROUND
  Insufficient information exists on comparing radiological differences in bone density of the regeneration rate in the alveolar bone of the maxilla and mandible following the creation of similar defects in both.
  
  
  METHODS
  Alveolar bone defects were created from five healthy Chacma baboons. Standardized x-ray images were acquired over time and the densities of the selected defect areas were measured pre-operatively, directly post-operatively and at three- and six weeks post-operatively. Differences in densities were statistically tested using ANOVA.
  
  
  RESULTS
  The maxilla was significantly more radiologically dense (p = 0.026) than the mandible pre- operatively. No differences were obtained between the maxilla and mandible directly postoperatively and three- and six weeks post-operatively respectively; i.e. densities were not significantly different at the different time points after the defects had been created (three weeks: t = 1.08, p = 0.30; six weeks: t = 1.35, p = 0.19; three to six weeks: t = 1.20, p =0.25). The increase in density in the mandible was 106% (8.9 ± 7.6%/time versus 4.3 ± 2.7%/time) over three weeks, 28% (15.0 ± 8.1%/time versus 11.7 ± 8.0%/time) over six weeks and 56% (12.5 ± 9.7%/time versus 8.0 ± 6.9%/time) over three-to-six weeks and was higher than in the maxilla over the same intervals.
  
  
  CONCLUSIONS
  Radiological examination with its standardized gray-scale analysis can be used to determine the difference in bone density of the maxilla and mandible. Although not statistically significant, the mandible healed at a faster rate than the maxilla, especially observed during the first three weeks after the defects were created.
authors.affiliation: Department Maxillo-Facial and Oral Surgery, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa. thinus.kotze@up.ac.za.
authors.forename: Marthinus J
authors.initials: MJ
authors.lastname: Kotze
authors.forename: Kurt-W
authors.initials: KW
authors.lastname: Bütow
authors.forename: Steve A
authors.initials: SA
authors.lastname: Olorunju
authors.forename: Harry F
authors.initials: HF
authors.lastname: Kotze
mesh_terms: D000539:Alveolar Process / Q000000981:diagnostic imaging / Q000254:growth & development*; D000818:Animals; D015519:Bone Density; D001861:Bone Regeneration; D008297:Male; D008334:Mandible / Q000000981:diagnostic imaging / Q000254:growth & development*; D008437:Maxilla / Q000000981:diagnostic imaging / Q000254:growth & development*; D010012:Osteogenesis / Q000502:physiology*; D048549:Papio ursinus; D011859:Radiography