title: Long Non-Coding RNAs Involved in Immune Responses.
abstract: A large number of human RNA transcripts, which do not encode proteins are defined as non-coding RNAs (ncRNAs). These ncRNAs are divided into two classes of different lengths; short and long ncRNAs. MicroRNAs are a major class of short ncRNAs, ~22 nucleotides in length that regulate gene expression at the post-transcriptional level. Long non-coding RNAs (lncRNAs) are more than 200 nucleotides in length and play roles in various biological pathways. In this review, we summarize the functions of lncRNAs which regulate immune responses.
authors.affiliation: Radioisotope Centre, The University of Tokyo , Tokyo , Japan.
authors.forename: Katsutoshi
authors.initials: K
authors.lastname: Imamura
authors.affiliation: Radioisotope Centre, The University of Tokyo , Tokyo , Japan.
authors.forename: Nobuyoshi
authors.initials: N
authors.lastname: Akimitsu
keywords: NEAT1; innate immune response; long non-coding RNA (lncRNA); translational repression