title: Sulfide synthesis through copper-catalyzed C-S bond formation under biomolecule-compatible conditions.
abstract: We report here an efficient and mild method for constructing C-S bonds. The reactions were carried out with Na2S2O3 as a sulfurating reagent, CuSO4 as a catalyst, and water as solvent without any surfactant. The products were achieved in moderate to excellent yields at room temperature under air. Notably, this reaction is compatible with various biomolecules including amino acids, oligosaccharides, nucleosides, proteins, and cell lysates.
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, Shanghai 200062, P. R. China. xfjiang@chem.ecnu.edu.cn.
authors.forename: Yonghong
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yiming
authors.initials: Y
authors.lastname: Li
authors.forename: Xiaomei
authors.initials: X
authors.lastname: Zhang
authors.forename: Xuefeng
authors.initials: X
authors.lastname: Jiang
mesh_terms: D000818:Animals; D001704:Biopolymers / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D002417:Cattle; D060326:Chemistry Techniques, Synthetic; D003300:Copper / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D013440:Sulfides / Q000138:chemical synthesis* / Q000737:chemistry*; D013455:Sulfur / Q000737:chemistry*
chemical_list: D001704:Biopolymers; D013440:Sulfides; D013455:Sulfur; D002244:Carbon; D003300:Copper