title: Hemodynamic response to resistance exercise with and without blood flow restriction in healthy subjects.
abstract: OBJECTIVE
  To compare the hemodynamic response during resistance exercise at high intensity (HI), low intensity (LI) and low intensity with blood flow restriction (LI-BFR) in healthy subjects.
  
  
  METHODS
  Twelve men performed three sets of unilateral knee extension exercises at LI-BFR and LI (15 repetitions; 20% of 1RM) and HI (8 repetitions; 80% of 1RM). The blood flow restriction was accomplished using a sphygmomanometer positioned on the thigh and inflated to the point of blood flow interruption (167·9 ± 16·6 mmHg). The hemodynamic variables were obtained by continuous beat-to-beat photoplethysmography. Rating of perceived exertion (RPE) and blood lactate were also measured.
  
  
  RESULTS
  The HI session showed higher values (P<0·05) in all sets than the LI and LI-BFR for diastolic blood pressure, heart rate and rate-pressure product. The LI-BFR showed higher values than the LI only in the 3rd set for systolic blood pressure, heart rate and rate-pressure product. Blood lactate was higher in the HI (4·2 ± 0·2 mmol) and LI-BFR (4·1 ± 0·3 mmol) than the LI (3·5 ± 0·3 mmol). Rating of perceived exertion was higher in the LI-BFR (7·9 ± 0·3) than the HI (6·4 ± 0·4) and LI (3·2 ± 0·4).
  
  
  CONCLUSIONS
  The LI-BFR session exhibited similar blood lactate to the HI, a higher rating of perceived response than the HI and LI, and equal or lower hemodynamic responses than the HI.
authors.affiliation: Research Group of Cardiovascular Response and Exercise, Londrina State University, Londrina, PR, Brazil.
authors.forename: Roberto
authors.initials: R
authors.lastname: Poton
authors.affiliation: Research Group of Cardiovascular Response and Exercise, Londrina State University, Londrina, PR, Brazil.
authors.forename: Marcos Doederlein
authors.initials: MD
authors.lastname: Polito
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D006801:Humans; D019344:Lactic Acid / Q000097:blood*; D008297:Male; D010807:Physical Endurance / Q000502:physiology*; D005082:Physical Exertion / Q000502:physiology*; D012016:Reference Values; D012039:Regional Blood Flow / Q000502:physiology; D015203:Reproducibility of Results; D055070:Resistance Training / Q000379:methods*; D012680:Sensitivity and Specificity; D014655:Vascular Resistance / Q000502:physiology
chemical_list: D019344:Lactic Acid
keywords: blood pressure; cardiovascular physiology; resistance training; strength; vascular occlusion