title: Partial hepatectomy for primary hepatic melanoma: a report of two cases and review of the literature.
abstract: Malignant melanoma is an extremely aggressive cancer arising from melanocytes, associated with the development of metastases in up to 20% of patients. Although the liver is a frequent metastatic site of malignant melanoma, primary hepatic melanoma (PHM) is rare. The treatment of PHM is controversial, and the prognosis for affected patients remains poor. We present two PHM patients who underwent partial hepatectomy at our institution and review the clinical and pathological data from these cases. Our results suggest that it is difficult to make a preoperative diagnosis of PHM without pathological results. For patients with resectable PHM, surgical resection is a potentially curative treatment.
authors.forename: Yuhua
authors.initials: Y
authors.lastname: Zhang
authors.forename: Zhiming
authors.initials: Z
authors.lastname: Hu
authors.forename: Weiding
authors.initials: W
authors.lastname: Wu
authors.forename: Jie
authors.initials: J
authors.lastname: Liu
authors.forename: Defei
authors.initials: D
authors.lastname: Hong
authors.affiliation: The hepatobiliary, Pancreatic and Minimal Invasive Surgery Department, Zhejiang Provincial People's Hospital, 158# Shangtang Road, Hangzhou, Zhejiang 310014, China. drzhangchengwu@126.com.
authors.forename: Chengwu
authors.initials: C
authors.lastname: Zhang
mesh_terms: D000368:Aged; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000601:surgery*; D008297:Male; D008545:Melanoma / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D011379:Prognosis