title: Complications of transrectal ultrasound-guided prostate biopsy: impact of prebiopsy enema.
abstract: OBJECTIVE
  Transrectal ultrasound (TRUS)-guided biopsy of the prostate is usually safe. However, some patients are hospitalized owing to complications from TRUS biopsy. We identified the risk factors for complications and effective preventive measures for treating complications after TRUS biopsy.
  
  
  METHODS
  Medical records and radiological images of 1,083 patients who underwent TRUS biopsy of the prostate over 10 years in Gyeongsang National University Hospital were examined retrospectively to investigate the correlation between complications after TRUS biopsy and preventive antibiotics, prebiopsy enema, number of biopsy cores, and pathological findings.
  
  
  RESULTS
  Complications occurred in 69 patients (6.4%). The complication rates of the 1,008 patients who received antibiotics and the 75 patients who did not were 6.3% and 8.0%, respectively (p=0.469). Complication rates of the pre-biopsy enema group (n=658) and the group without prebiopsy enema (n=425) were 4.7% and 8.9%, respectively (p=0.007). Complication rates of the 6-core biopsy group (n=41) and the 12-core biopsy group (n=955) were 7.3% and 6.3%, respectively (p=0.891). Complication rates of the prostate cancer group (n=306) and the no prostate cancer group (n=713) were 6.2% and 6.6%, respectively (p=0.740).
  
  
  CONCLUSIONS
  A prebiopsy enema was associated with a reduced risk of complications after TRUS biopsy. Preventive antibiotics, number of biopsy cores, and pathological findings did not significantly influence the complication rate.
authors.affiliation: Department of Urology, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, Korea.
authors.forename: Sung Chul
authors.initials: SC
authors.lastname: Kam
authors.affiliation: Department of Urology, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, Korea.
authors.forename: See Min
authors.initials: SM
authors.lastname: Choi
authors.affiliation: Department of Urology, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, Korea.
authors.forename: Sol
authors.initials: S
authors.lastname: Yoon
authors.affiliation: Department of Urology, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, Korea.
authors.forename: Jae Hui
authors.initials: JH
authors.lastname: Choi
authors.affiliation: Department of Urology, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, Korea.
authors.forename: Seong Hyun
authors.initials: SH
authors.lastname: Lee
authors.affiliation: Department of Urology, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, Korea.
authors.forename: Jeong Seok
authors.initials: JS
authors.lastname: Hwa
authors.affiliation: Department of Urology, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, Korea.
authors.forename: Ky Hyun
authors.initials: KH
authors.lastname: Chung
authors.affiliation: Department of Urology, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, Korea.
authors.forename: Jae Seog
authors.initials: JS
authors.lastname: Hyun
mesh_terms: D000368:Aged; D019160:Endosonography; D004733:Enema / Q000379:methods*; D006801:Humans; D061705:Image-Guided Biopsy / Q000009:adverse effects* / Q000379:methods; D015994:Incidence; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology*; D011472:Prostatitis / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D012007:Rectum; D056910:Republic of Korea / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D019462:Syncope, Vasovagal / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D016055:Urinary Retention / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*
keywords: Biopsy; Complications; Enema; Prostate