title: Implications for human adipose-derived stem cells in plastic surgery.
abstract: Adipose-derived stem cells (ADSCs) are a subset of mesenchymal stem cells (MSCs) that possess many of the same regenerative properties as other MSCs. However, the ubiquitous presence of ADSCs and their ease of access in human tissue have led to a burgeoning field of research. The plastic surgeon is uniquely positioned to harness this technology because of the relative frequency in which they perform procedures such as liposuction and autologous fat grafting. This review examines the current landscape of ADSC isolation and identification, summarizes the current applications of ADSCs in the field of plastic surgery, discusses the risks associated with their use, current barriers to universal clinical translatability, and surveys the latest research which may help to overcome these obstacles.
authors.affiliation: Department of Plastic Surgery, University of California, Irvine, Orange, CA, USA.
authors.forename: Derek A
authors.initials: DA
authors.lastname: Banyard
authors.forename: Ara A
authors.initials: AA
authors.lastname: Salibian
authors.forename: Alan D
authors.initials: AD
authors.lastname: Widgerow
authors.forename: Gregory R D
authors.initials: GR
authors.lastname: Evans
mesh_terms: D000273:Adipose Tissue / Q000166:cytology*; D002469:Cell Separation; D006801:Humans; D033581:Stem Cell Transplantation; D013234:Stem Cells / Q000166:cytology*; D013518:Surgery, Plastic
keywords: adipose-derived stem cell; lipotransfer; mesenchymal stem cell; stem cell