title: Bioactive Food Components as Dietary Intervention for Cystic Fibrosis.
abstract: Cystic fibrosis (CF) is a genetic disorder that can lead to death at an early age. CF is characterized by respiratory infection, airway obstruction, inflammation, and eventually end-stage lung failure. CF also damages pancreatic exocrine function resulting in serious complications such as nutritional deficiencies. Current therapy to this multisystem disease requires the practice of both pharmacological and nutritional approaches. Growing evidence shows that bioactive food components, such as polyunsaturated fatty acids, phytochemicals, and antioxidants, have beneficial effects in the management of CF disease. This review will summarize the current status of bioactive compounds in CF therapy.
authors.affiliation: Nutraceuticals and Functional Food Research and Development Center, Prince of Songkla University, Kanchanavanich Road, Hat-Yai, Songkhla, Thailand. nualpun.s@psu.ac.th.
authors.forename: Nualpun
authors.initials: N
authors.lastname: Sirinupong
authors.forename: Zhe
authors.initials: Z
authors.lastname: Yang
mesh_terms: D000975:Antioxidants / Q000627:therapeutic use*; D003550:Cystic Fibrosis / Q000178:diet therapy* / Q000473:pathology; D019587:Dietary Supplements; D005231:Fatty Acids, Unsaturated / Q000627:therapeutic use*; D055951:Functional Food; D006801:Humans; D009752:Nutritional Status; D064209:Phytochemicals / Q000627:therapeutic use*
chemical_list: D000975:Antioxidants; D005231:Fatty Acids, Unsaturated; D064209:Phytochemicals