title: Paraformaldehyde and methanol as C1  feedstocks in metal-catalyzed C-C couplings of π-unsaturated reactants: beyond hydroformylation.
abstract: Ruthenium-catalyzed reductive couplings of paraformaldehyde with dienes, alkynes, and allenes provide access to products of hydrohydroxymethylation that cannot be formed selectively under the conditions of hydroformylation. In certain cases, the regioselectivity of the CC coupling can be inverted by using nickel catalysts. With iridium catalysts, methanol engages in redox-neutral regioselective hydrohydroxymethylations.
authors.affiliation: University of Texas at Austin, Department of Chemistry, 105 E 24th St. Welch Hall (A5300), Austin, TX 78712-1167 (USA).
authors.forename: Brannon
authors.initials: B
authors.lastname: Sam
authors.forename: Bernhard
authors.initials: B
authors.lastname: Breit
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Krische
keywords: industrial chemistry; iridium; metal catalysis; nickel; ruthenium; transfer hydrogenation