title: Catalytic highly enantioselective transfer hydrogenation of β-trifluoromethyl nitroalkenes. An easy and general entry to optically active β-trifluoromethyl amines.
abstract: In the presence of a thiourea catalyst, β-CF3 nitroalkenes react with Hantzsch esters in a highly enantioselective fashion, giving a broad range of β-CF3 amine precursors with a tertiary stereocentre at the β-position. This reaction represents the first general catalytic enantioselective approach to this important class of β-CF3 amines.
authors.affiliation: Chimie ParisTech - École Nationale Supérieure de Chimie de Paris, 11, rue Pierre et Marie Curie, 75231 Paris Cedex 05, France.
authors.forename: Emilie
authors.initials: E
authors.lastname: Martinelli
authors.forename: Anna Chiara
authors.initials: AC
authors.lastname: Vicini
authors.forename: Michele
authors.initials: M
authors.lastname: Mancinelli
authors.forename: Andrea
authors.initials: A
authors.lastname: Mazzanti
authors.forename: Paolo
authors.initials: P
authors.lastname: Zani
authors.forename: Luca
authors.initials: L
authors.lastname: Bernardi
authors.forename: Mariafrancesca
authors.initials: M
authors.lastname: Fochi