title: Microwave-assisted synthesis and biological evaluation of dihydropyrimidinone derivatives as anti-inflammatory, antibacterial, and antifungal agents.
abstract: A simple protocol for the efficient preparation of aryl and heteroaryl substituted dihydropyrimidinone has been achieved via initial Knoevenagel, subsequent addition, and final cyclization of aldehyde, ethylcyanoacetate, and guanidine nitrate in the presence of piperidine as a catalyst in solvent-free under microwave irradiation. The synthesized compounds showed a good anti-inflammatory, antibacterial, and antifungal activity.
authors.affiliation: Laboratory of Heterocycles, School of Studies in Chemistry and Biochemistry, Vikram University, Ujjain, Madhya Pradesh 456010, India.
authors.forename: Anjna
authors.initials: A
authors.lastname: Bhatewara
authors.affiliation: Laboratory of Heterocycles, School of Studies in Chemistry and Biochemistry, Vikram University, Ujjain, Madhya Pradesh 456010, India.
authors.forename: Srinivasa Rao
authors.identifier: 0000-0003-3490-7033
authors.initials: SR
authors.lastname: Jetti
authors.affiliation: Laboratory of Heterocycles, School of Studies in Chemistry and Biochemistry, Vikram University, Ujjain, Madhya Pradesh 456010, India.
authors.forename: Tanuja
authors.initials: T
authors.lastname: Kadre
authors.affiliation: Laboratory of Heterocycles, School of Studies in Chemistry and Biochemistry, Vikram University, Ujjain, Madhya Pradesh 456010, India.
authors.forename: Pradeep
authors.initials: P
authors.lastname: Paliwal
authors.affiliation: Laboratory of Heterocycles, School of Studies in Chemistry and Biochemistry, Vikram University, Ujjain, Madhya Pradesh 456010, India.
authors.forename: Shubha
authors.initials: S
authors.lastname: Jain