title: Innate lymphoid cells and the skin.
abstract: Innate lymphoid cells are an emerging family of effector cells that contribute to lymphoid organogenesis, metabolism, tissue remodelling and protection against infections. They maintain homeostatic immunity at barrier surfaces such as lung, skin and gut (Nature 464:1367-1371, 2010, Nat Rev Immunol 13: 145-149, 2013). Several human and mouse studies suggest a role for innate lymphoid cells in inflammatory skin conditions including atopic eczema and psoriasis. Here we review the innate lymphoid cell family and discuss their function in the skin and during inflammation.
authors.forename: Maryam
authors.initials: M
authors.lastname: Salimi
authors.affiliation: Department of Medicine, MRC Human Immunology Unit, NIHR Biomedical Research Centre, Radcliffe University of Oxford, Oxford, UK. Graham.ogg@ndm.ox.ac.uk.
authors.forename: Graham
authors.initials: G
authors.lastname: Ogg
mesh_terms: D000818:Animals; D016207:Cytokines / Q000378:metabolism; D003876:Dermatitis, Atopic / Q000276:immunology*; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D007113:Immunity, Innate; D008214:Lymphocytes / Q000166:cytology / Q000276:immunology* / Q000378:metabolism; D051379:Mice; D011565:Psoriasis / Q000276:immunology*; D012867:Skin / Q000276:immunology* / Q000378:metabolism
chemical_list: D016207:Cytokines