title: Effect of the ingestion of the palm oil and glutamine in serum levels of GLP-1, PYY and glycemia in diabetes mellitus type 2 patients submitted to metabolic surgery.
abstract: BACKGROUND
  Incretins are hormones produced by the intestine and can stimulate the secretion of insulin, helping to diminish the post-prandial glycemia. The administration of an emulsion of palm oil can help in the maintenance of the weight, and can increase circulating incretins levels. Glutamine increases the concentration of incretins in diabetic people. Both can help in metabolic syndrome.
  
  
  OBJECTIVE
  To analyze the effects of ingestion of palm oil and glutamine in glycemia and in incretins in patients with diabetes submitted to surgical duodenojejunal exclusion with ileal interposition without gastrectomy.
  
  
  METHODS
  Eleven diabetic type 2 patients were included and were operated. They were called to laboratory follow-up without eating anything between eight and 12 hours. They had there blood collected after the stimulus of the palm oil and glutamine taken in different days. For the hormonal doses were used ELISA kits.
  
  
  RESULTS
  The glycemia showed a meaningful fall between the fast and two hours after the stimulus of the palm oil (p=0,018). With the glutamine the GLP-1 showed an increase between the fast and one hour (p=0,32), the PYY showed an important increase between the fast and one hour after the stimulus (p=0,06), the glycemia showed a meaningful fall after two hours of the administration of the stimulus (p=0,03).
  
  
  CONCLUSIONS
  Palm oil and glutamine can influence intestinal peptides and glucose.
authors.affiliation: Universidade Federal do Triângulo Mineiro, Uberaba, MG, Brazil.
authors.forename: Tharsus Dias
authors.initials: TD
authors.lastname: Takeuti
authors.affiliation: Universidade Federal do Triângulo Mineiro, Uberaba, MG, Brazil.
authors.forename: Guilherme Azevedo
authors.initials: GA
authors.lastname: Terra
authors.affiliation: Universidade Federal do Triângulo Mineiro, Uberaba, MG, Brazil.
authors.forename: Alex Augusto
authors.initials: AA
authors.lastname: da Silva
authors.affiliation: Universidade Federal do Triângulo Mineiro, Uberaba, MG, Brazil.
authors.forename: Júverson Alves
authors.initials: JA
authors.lastname: Terra
authors.affiliation: Universidade Federal do Triângulo Mineiro, Uberaba, MG, Brazil.
authors.forename: Luci Mara
authors.initials: LM
authors.lastname: da Silva
authors.affiliation: Universidade Federal do Triângulo Mineiro, Uberaba, MG, Brazil.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Crema
mesh_terms: D000328:Adult; D050110:Bariatric Surgery; D001786:Blood Glucose / Q000032:analysis*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D004435:Eating; D005260:Female; D052216:Glucagon-Like Peptide 1 / Q000097:blood*; D005973:Glutamine / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D000073878:Palm Oil; D019894:Peptide YY / Q000097:blood*; D010938:Plant Oils / Q000008:administration & dosage*; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D010938:Plant Oils; D005973:Glutamine; D019894:Peptide YY; D000073878:Palm Oil; D052216:Glucagon-Like Peptide 1