title: Effects of dipeptidyl peptidase IV inhibitor sitagliptin on immunological parameters of lymphocytes in intact animals and animals with experimental autoimmune process.
abstract: The effects of dipeptidyl peptidase IV inhibitor sitagliptin on immunological parameters were studied in animals with experimental autoimmune process. The effects of the drug administered in preventive (before manifestation of autoimmune processes) and therapeutic (after manifestation of autoimmune process) modes were studied.
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia, robin@physiol.ru.
authors.forename: M V
authors.initials: MV
authors.lastname: Robinson
authors.forename: E V
authors.initials: EV
authors.lastname: Mel'nikova
authors.forename: V A
authors.initials: VA
authors.lastname: Trufakin
mesh_terms: D000818:Animals; D001327:Autoimmune Diseases / Q000276:immunology*; D054873:Dipeptidyl-Peptidase IV Inhibitors / Q000494:pharmacology*; D004353:Drug Evaluation, Preclinical; D008198:Lymph Nodes / Q000187:drug effects / Q000276:immunology; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology*; D008297:Male; D008808:Mice, Inbred CBA; D011719:Pyrazines / Q000494:pharmacology*; D000068900:Sitagliptin Phosphate; D013154:Spleen / Q000187:drug effects / Q000276:immunology; D013950:Thymus Gland / Q000187:drug effects / Q000276:immunology; D014230:Triazoles / Q000494:pharmacology*
chemical_list: D054873:Dipeptidyl-Peptidase IV Inhibitors; D011719:Pyrazines; D014230:Triazoles; D000068900:Sitagliptin Phosphate