title: Current molecular methods in epidemiological typing of Acinetobacter baumannii.
abstract: The emergence of Acinetobacter baumannii during recent decades as an important nosocomial pathogen responsible of worldwide, intensively documented, outbreaks has resulted in a need for effective epidemiological typing methods. Throughout the years, many typing methods for A. baumannii epidemiological studies have been proposed from phenotypic to molecular methods. Currently, the use of phenotypic typing methods have declined considerably and been progressively replaced by molecular methods. In this review, we introduce the current molecular methods available for A. baumannii typing. Each method has its own advantages and disadvantages, and the selection of an appropriate genotyping method depends on studied objectives. This review sheds light on questions in different epidemiological settings and most molecular methods used to fit these objectives.
authors.affiliation: L'UNAM Université, Université d'Angers, Groupe d'Etude des Interactions Hôte-Pathogène, UPRES EA3142, Institut de Biologie en Santé - IRIS, CHU, 4, rue Larrey, 49933 Angers cedex, France.
authors.forename: Rayane
authors.initials: R
authors.lastname: Rafei
authors.forename: Marie
authors.initials: M
authors.lastname: Kempf
authors.forename: Matthieu
authors.initials: M
authors.lastname: Eveillard
authors.forename: Fouad
authors.initials: F
authors.lastname: Dabboussi
authors.forename: Monzer
authors.initials: M
authors.lastname: Hamze
authors.forename: Marie-Laure
authors.initials: ML
authors.lastname: Joly-Guillou
mesh_terms: D000151:Acinetobacter Infections / Q000453:epidemiology* / Q000382:microbiology*; D040981:Acinetobacter baumannii / Q000145:classification* / Q000235:genetics*; D015373:Bacterial Typing Techniques / Q000379:methods* / Q000639:trends; D006801:Humans; D017720:Molecular Epidemiology / Q000379:methods
keywords: Acinetobacter baumannii; epidemiological study; molecular typing method; outbreak