title: Maternal immunization: opportunities for scientific advancement.
abstract: Maternal immunization is an effective strategy to prevent and/or minimize the severity of infectious diseases in pregnant women and their infants. Based on the success of vaccination programs to prevent maternal and neonatal tetanus, maternal immunization has been well received in the United States and globally as a promising strategy for the prevention of other vaccine-preventable diseases that threaten pregnant women and infants, such as influenza and pertussis. Given the promise for reducing the burden of infectious conditions of perinatal significance through the development of vaccines against relevant pathogens, the Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH) sponsored a series of meetings to foster progress toward clinical development of vaccines for use in pregnancy. A multidisciplinary group of stakeholders convened at the NIH in December 2013 to identify potential barriers and opportunities for scientific advancement in maternal immunization.
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital of the University of Pittsburgh Medical Center, Pennsylvania.
authors.forename: Richard H
authors.initials: RH
authors.lastname: Beigi
authors.affiliation: Department of Obstetrics and Gynecology, Vanderbilt University, Nashville, Tennessee Vanderbilt Vaccine Research Program, Department of Pediatrics, Vanderbilt University, Nashville, Tennessee.
authors.forename: Kimberly B
authors.initials: KB
authors.lastname: Fortner
authors.affiliation: Department of Pediatrics Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas.
authors.forename: Flor M
authors.initials: FM
authors.lastname: Munoz
authors.affiliation: Department of Food and Drug Administration, Center for Biologics Evaluation and Research, Office of Vaccines Research and Review, Silver Spring, Maryland.
authors.forename: Jeff
authors.initials: J
authors.lastname: Roberts
authors.affiliation: National Vaccine Program Office, Office of the Assistant Secretary for Health, US Department of Health and Human Services, Washington, D.C.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Gordon
authors.affiliation: GlaxoSmithKline Vaccines, King of Prussia, Pennsylvania.
authors.forename: Htay Htay
authors.initials: HH
authors.lastname: Han
authors.affiliation: Novavax, Inc, Gaithersburg, Maryland.
authors.forename: Greg
authors.initials: G
authors.lastname: Glenn
authors.affiliation: Novartis Vaccines and Diagnostics, Inc, Cambridge, Massachusetts.
authors.forename: Philip R
authors.initials: PR
authors.lastname: Dormitzer
authors.affiliation: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
authors.forename: Xing Xing
authors.initials: XX
authors.lastname: Gu
authors.affiliation: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
authors.forename: Jennifer S
authors.initials: JS
authors.lastname: Read
authors.affiliation: Vanderbilt Vaccine Research Program, Department of Pediatrics, Vanderbilt University, Nashville, Tennessee.
authors.forename: Kathryn
authors.initials: K
authors.lastname: Edwards
authors.affiliation: Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas Department of Medicine, Baylor College of Medicine, Houston, Texas.
authors.forename: Shital M
authors.initials: SM
authors.lastname: Patel
authors.affiliation: Department of Obstetrics and Gynecology, Duke University, Durham, North Carolina.
authors.forename: Geeta K
authors.initials: GK
authors.lastname: Swamy
mesh_terms: D002986:Clinical Trials as Topic; D003140:Communicable Disease Control; D005260:Female; D006801:Humans; D007112:Immunity, Maternally-Acquired; D007114:Immunization; D017589:Immunization Programs; D007223:Infant; D007252:Influenza Vaccines; D007251:Influenza, Human / Q000517:prevention & control; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000517:prevention & control*; D013742:Tetanus / Q000517:prevention & control; D014481:United States; D014612:Vaccines / Q000008:administration & dosage / Q000009:adverse effects / Q000276:immunology; D014917:Whooping Cough / Q000517:prevention & control
chemical_list: D007252:Influenza Vaccines; D014612:Vaccines
keywords: immunization; maternal; pregnancy; research; vaccines