title: Prognosis: does exercise training reduce adverse events in heart failure?
abstract: Patients with heart failure (HF) were once discouraged from participating in exercise programs because of concerns regarding safety and the potential for harm to an already damaged myocardium. However, studies over the last 3 decades have provided extensive insights into both the health outcome benefits of exercise and the mechanisms underlying these benefits. Studies on the outcome benefits of exercise training, including mortality and hospitalization, have been convincing. This article reviews the physiologic benefits of exercise training in HF, studies on exercise training in women, results and implications of the HF-ACTION trial, and recent meta-analyses using the Cochrane data base.
authors.affiliation: Cardiology Division, Palo Alto VA Health Care System, Stanford University, Cardiology 111C, 3801 Miranda Avenue, Palo Alto, CA 94304, USA. Electronic address: drj993@aol.com.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Myers
authors.affiliation: Division of Cardiovascular Medicine, Henry Ford Hospital, 6525 Second Avenue, Detroit, MI 48202, USA.
authors.forename: Clinton A
authors.initials: CA
authors.lastname: Brawner
authors.affiliation: Alberta Cardiovascular and Stroke Research Centre (ABACUS), Mazankowski Alberta Heart Institute, University of Alberta, 3-16 Corbett Hall, Edmonton, AB T6G 2G4, Canada.
authors.forename: Mark J F
authors.initials: MJ
authors.lastname: Haykowsky
authors.affiliation: Graduate School of Education, University of Exeter Medical School, Veysey Building, Salmon Pool Lane, Exeter EX2 4SG, UK; National Institute of Public Health, University of Southern Denmark, Campusvej 55, DK-5230, Odense M, Denmark.
authors.forename: Rod S
authors.initials: RS
authors.lastname: Taylor
mesh_terms: D018450:Disease Progression; D005081:Exercise Therapy / Q000379:methods*; D017079:Exercise Tolerance / Q000502:physiology*; D006333:Heart Failure / Q000503:physiopathology* / Q000534:rehabilitation*; D006801:Humans; D011379:Prognosis; D011788:Quality of Life
keywords: Aerobic capacity; Cardiac output; Cardiac rehabilitation; Oxygen uptake; Prognosis