title: Effect of testosterone replacement treatment on constitutional and sexual symptoms in type 2 diabetic men: need for rules.
abstract: In a recent publication, Gianatti and colleagues investigated the effect of testosterone treatment in obese, aging men with type 2 diabetes (T2D) with mild to moderate symptoms, a modest reduction in testosterone levels, mild to moderate aging male symptoms, and erectile dysfunction. [1] The authors could not show any significant improvement in constitutional or sexual symptoms in this group of men. This randomized double-blind, parallel, and placebo-controlled trial among other critically emphasizes the increased testosterone prescriptions worldwide and together with other corroborating or contradictory studies awakes the need for guidelines in the androgen replacement treatment.
authors.affiliation: Department of Urology, University of Ioannina, Medical School, Ioannina, Greece.
authors.forename: Fotios
authors.initials: F
authors.lastname: Dimitriadis
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Sofikitis
mesh_terms: D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D007172:Erectile Dysfunction / Q000188:drug therapy*; D006801:Humans; D007989:Libido / Q000187:drug effects*; D008297:Male; D013739:Testosterone / Q000031:analogs & derivatives*
chemical_list: D013739:Testosterone