title: Update for the practicing pathologist: The International Consultation On Urologic Disease-European association of urology consultation on bladder cancer.
abstract: The International Consultations on Urological Diseases are international consensus meetings, supported by the World Health Organization and the Union Internationale Contre le Cancer, which have occurred since 1981. Each consultation has the goal of convening experts to review data and provide evidence-based recommendations to improve practice. In 2012, the selected subject was bladder cancer, a disease which remains a major public health problem with little improvement in many years. The proceedings of the 2nd International Consultation on Bladder Cancer, which included a 'Pathology of Bladder Cancer Work Group,' have recently been published; herein, we provide a summary of developments and consensus relevant to the practicing pathologist. Although the published proceedings have tackled a comprehensive set of issues regarding the pathology of bladder cancer, this update summarizes the recommendations regarding selected issues for the practicing pathologist. These include guidelines for classification and grading of urothelial neoplasia, with particular emphasis on the approach to inverted lesions, the handling of incipient papillary lesions frequently seen during surveillance of bladder cancer patients, descriptions of newer variants, and terminology for urine cytology reporting.
authors.affiliation: Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
authors.forename: Mahul B
authors.initials: MB
authors.lastname: Amin
authors.affiliation: Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
authors.forename: Steven C
authors.initials: SC
authors.lastname: Smith
authors.affiliation: Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
authors.forename: Victor E
authors.initials: VE
authors.lastname: Reuter
authors.affiliation: Department of Pathology, Johns Hopkins Hospital, Baltimore, MD, USA.
authors.forename: Jonathan I
authors.initials: JI
authors.lastname: Epstein
authors.affiliation: Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA.
authors.forename: David J
authors.initials: DJ
authors.lastname: Grignon
authors.affiliation: Department of Pathology, University of California San Diego, San Diego, CA, USA.
authors.forename: Donna E
authors.initials: DE
authors.lastname: Hansel
authors.affiliation: Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
authors.forename: Oscar
authors.initials: O
authors.lastname: Lin
authors.affiliation: Department of Pathology, Cleveland Clinic Foundation, Cleveland, OH, USA.
authors.forename: Jesse K
authors.initials: JK
authors.lastname: McKenney
authors.affiliation: Section of Pathological Anatomy, Polytechnic University of Medicine, United Hospitals, Ancona, Italy.
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Montironi
authors.affiliation: Department of Pathology, University of Chicago, Chicago, IL, USA.
authors.forename: Gladell P
authors.initials: GP
authors.lastname: Paner
authors.affiliation: Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
authors.forename: Hikmat A
authors.initials: HA
authors.lastname: Al-Ahmadie
authors.affiliation: Pathology Section, Fundacio Puigvert, Universitat Autónoma de Barcelona, Barcelona, Spain.
authors.forename: Ferran
authors.initials: F
authors.lastname: Algaba
authors.affiliation: Department of Pathology, Johns Hopkins Hospital, Baltimore, MD, USA.
authors.forename: Syed
authors.initials: S
authors.lastname: Ali
authors.affiliation: Department of Pathology, Mexican Oncology Hospital, Mexico City, Mexico.
authors.forename: Isabel
authors.initials: I
authors.lastname: Alvarado-Cabrero
authors.affiliation: Institute of Pathology, University Hospital Basel, Basel, Switzerland.
authors.forename: Lukas
authors.initials: L
authors.lastname: Bubendorf
authors.affiliation: Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA.
authors.forename: Liang
authors.initials: L
authors.lastname: Cheng
authors.affiliation: Division of Anatomic Pathology, Mayo Clinic, Rochester, MN, USA.
authors.forename: John C
authors.initials: JC
authors.lastname: Cheville
authors.affiliation: Institute of Pathology, University Hospital Bonn, Bonn, Germany.
authors.forename: Glen
authors.initials: G
authors.lastname: Kristiansen
authors.affiliation: Department of Pathology, University of Miami Miller School of Medicine, Miami, FL, USA.
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Cote
authors.affiliation: Department of Pathology, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand.
authors.forename: Brett
authors.initials: B
authors.lastname: Delahunt
authors.affiliation: Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA.
authors.forename: John N
authors.initials: JN
authors.lastname: Eble
authors.affiliation: Department of Pathology and Laboratory Medicine, Tufts Medical Center, Boston, MA, USA.
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Genega
authors.affiliation: Department of Pathology, Beaumont Hospital, Dublin, Ireland.
authors.forename: Christian
authors.initials: C
authors.lastname: Gulmann
authors.affiliation: Institute of Pathology, University Erlangen-Nürnberg, Erlangen, Germany.
authors.forename: Arndt
authors.initials: A
authors.lastname: Hartmann
authors.affiliation: Institute of Pathology, Medical University Graz, Graz, Austria.
authors.forename: Cord
authors.initials: C
authors.lastname: Langner
authors.affiliation: Unit of Anatomical Pathology, Cordoba University Medical School, Faculty of Medicine, Cordoba, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Lopez-Beltran
authors.affiliation: Department of Pathology, Cleveland Clinic Foundation, Cleveland, OH, USA.
authors.forename: Cristina
authors.initials: C
authors.lastname: Magi-Galluzzi
authors.affiliation: Department of Pathology, University of Miami Miller School of Medicine, Miami, FL, USA.
authors.forename: Jorda
authors.initials: J
authors.lastname: Merce
authors.affiliation: Department of Pathology, Johns Hopkins Hospital, Baltimore, MD, USA.
authors.forename: George J
authors.initials: GJ
authors.lastname: Netto
authors.affiliation: James Homer Wright Pathology Laboratories, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
authors.forename: Esther
authors.initials: E
authors.lastname: Oliva
authors.affiliation: Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.
authors.forename: Priya
authors.initials: P
authors.lastname: Rao
authors.affiliation: Department of Pathology and Genomic Medicine, The Methodist Hospital Physician Organization, Weill Cornell Medical College of Cornell University, Houston, TX, USA.
authors.forename: Jae Y
authors.initials: JY
authors.lastname: Ro
authors.affiliation: Department Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.
authors.forename: John R
authors.initials: JR
authors.lastname: Srigley
authors.affiliation: Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
authors.forename: Satish K
authors.initials: SK
authors.lastname: Tickoo
authors.affiliation: Department of Pathology, Japanese Red Cross Nagoya Daini Hospital, Nagoya, Japan.
authors.forename: Toyonori
authors.initials: T
authors.lastname: Tsuzuki
authors.affiliation: Department of Pathology, University of Miami Miller School of Medicine, Miami, FL, USA.
authors.forename: Saleem A
authors.initials: SA
authors.lastname: Umar
authors.affiliation: Department of Urology, University of Miami Miller School of Medicine, Miami, FL, USA.
authors.forename: Theo
authors.initials: T
authors.lastname: Van der Kwast
authors.affiliation: James Homer Wright Pathology Laboratories, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
authors.forename: Robert H
authors.initials: RH
authors.lastname: Young
authors.affiliation: Department of Pathology, University of Miami Miller School of Medicine, Miami, FL, USA.
authors.forename: Mark S
authors.initials: MS
authors.lastname: Soloway
mesh_terms: D006801:Humans; D001749:Urinary Bladder Neoplasms