title: [The dependence of lipid peroxidation state and the antioxidant system of the myocardium from the thyroid status during short action of stressors].
abstract: In experiments at 78 adult white outbred male rats were demonstrated that experimental hypothyroidism (injection of 25 mg/kg merkazolil within 20 days) stimulates, while small doses of L-thyroxine (1.5-3.0 μg/kg within 28 days) limit the intensification of lipid peroxidation in the myocardium under short exposure to stressors of a different nature: physical (t 4-5 °C within 30 minutes), chemical (injection of 25% ethanol at a dose of 3.5 g/kg body weight), and emotional (free swimming of rats in the cage within 30 minutes) by influence on the activity of enzymatic (superoxide dismutase and catalase) and non-enzymatic (reduced glutathione) components of the antioxidant system.
authors.forename: I V
authors.initials: IV
authors.lastname: Gorodetskaia
authors.forename: O V
authors.initials: OV
authors.lastname: Evdokimova
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D013956:Antithyroid Agents / Q000009:adverse effects* / Q000494:pharmacology; D007037:Hypothyroidism / Q000139:chemically induced / Q000378:metabolism*; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D008713:Methimazole / Q000009:adverse effects* / Q000494:pharmacology; D009206:Myocardium / Q000378:metabolism*; D051381:Rats; D013312:Stress, Physiological / Q000187:drug effects*
chemical_list: D000975:Antioxidants; D013956:Antithyroid Agents; D008713:Methimazole