title: Headaches as a presenting symptom of linear morphea en coup de sabre.
abstract: Linear morphea en coup de sabre (ECDS) is a form of localized scleroderma that predominantly affects the pediatric population, with a median age of 10 years at presentation. The existence of neurologic findings in association with ECDS has been well described in the literature. Here we describe 4 patients with ECDS who presented with headaches, which were typical migraines in 3 of the patients. The headaches preceded the onset of cutaneous findings by at least 6 months. Our patients' cases emphasize both the importance of recognizing headaches as a harbinger of ECDS and the necessity of performing thorough cutaneous examination in patients with unexplained headaches or other neurologic disease.
authors.affiliation: Departments of Dermatology and Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois;
authors.forename: Ingrid
authors.initials: I
authors.lastname: Polcari
authors.affiliation: Department of Dermatology, University of Rochester School of Medicine, Rochester, New York; and.
authors.forename: Amanda
authors.initials: A
authors.lastname: Moon
authors.affiliation: Departments of Dermatology and Pediatrics, School of Medicine, University of California-San Francisco, San Francisco, California.
authors.forename: Erin F
authors.initials: EF
authors.lastname: Mathes
authors.affiliation: Department of Dermatology, University of Rochester School of Medicine, Rochester, New York; and.
authors.forename: Elaine S
authors.initials: ES
authors.lastname: Gilmore
authors.affiliation: Departments of Dermatology and Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois; apaller@northwestern.edu.
authors.forename: Amy S
authors.initials: AS
authors.lastname: Paller
mesh_terms: D000293:Adolescent; D001706:Biopsy; D001921:Brain / Q000473:pathology; D002648:Child; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005260:Female; D006261:Headache / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008727:Methotrexate / Q000627:therapeutic use; D008881:Migraine Disorders / Q000188:drug therapy / Q000209:etiology*; D011241:Prednisone / Q000627:therapeutic use; D012535:Scalp / Q000473:pathology; D012594:Scleroderma, Localized / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology
chemical_list: D011241:Prednisone; D008727:Methotrexate
keywords: children; female; humans; male; migraine headache; neurologic; scalp dermatoses/complications; scalp dermatoses/drug therapy; scalp dermatoses/pathology; scleroderma, localized/complications; scleroderma, localized/drug therapy; scleroderma, localized/pathology