title: Therapeutic potential of human adipose-derived stem cells in neurological disorders.
abstract: Stem cell therapy has been noted as a novel strategy to various diseases including neurological disorders such as Alzheimer's disease, Parkinson's disease, stroke, amyotrophic lateral sclerosis, and Huntington's disease that have no effective treatment available to date. The adipose-derived stem cells (ASCs), mesenchymal stem cells (MSCs) isolated from adipose tissue, are well known for their pluripotency with the ability to differentiate into various types of cells and immuno-modulatory property. These biological features make ASCs a promising source for regenerative cell therapy in neurological disorders. Here we discuss the recent progress of regenerative therapies in various neurological disorders utilizing ASCs.
authors.affiliation: Department of Pharmacology, College of Medicine, Neuroscience Research Institute, Gachon University, Korea.
authors.forename: Keun-A
authors.initials: KA
authors.lastname: Chang
authors.forename: Jun-Ho
authors.initials: JH
authors.lastname: Lee
authors.forename: Yoo-Hun
authors.initials: YH
authors.lastname: Suh
mesh_terms: D000273:Adipose Tissue / Q000166:cytology*; D000544:Alzheimer Disease / Q000628:therapy; D000690:Amyotrophic Lateral Sclerosis / Q000628:therapy; D000818:Animals; D002454:Cell Differentiation; D064987:Cell- and Tissue-Based Therapy / Q000379:methods* / Q000639:trends*; D006801:Humans; D006816:Huntington Disease / Q000628:therapy; D051379:Mice; D009422:Nervous System Diseases / Q000628:therapy*; D010300:Parkinson Disease / Q000628:therapy; D039904:Pluripotent Stem Cells / Q000166:cytology / Q000637:transplantation*; D044968:Regenerative Medicine / Q000379:methods* / Q000639:trends*; D033581:Stem Cell Transplantation / Q000379:methods* / Q000639:trends*