title: EFFECT OF COPPER OXIDE NANOPARTICLES TO SHEEPSHEAD MINNOW (CYPRINODON VARIEGATUS) AT DIFFERENT SALINITIES.
abstract: Nanotechnologies research has become a significant priority worldwide. Many engineered nano-sized materials have been increasingly used in consumer products. But the adverse effects of these nanoparticles on the environment and organisms have recently drawn much attention. The present study investigated the effects of different concentrations of copper oxide nanoparticles (CuO NPs) on the sheepshead minnow (Cyprinodon variegatus) at different salinity regimes, since it is able to withstand a wide range of salinities. The results indicated that CuO NPs could cause behavioral changes in the fish, such as increased mucus secretion, less general activity and loss of equilibrium. No mortality was observed at the presence of CuO NPs during the experiments. But higher oxidative stress was determined at half strength seawater than seawater exposure medium, which can be associated with the decreasing toxicity of CuO NPs as salinity increases. In addition, Cu contents in the tissues of the fish were significantly higher (p<0.05) in the low salinity. The order of Cu accumulation in the fish's organs was intestine > gills > liver.
authors.affiliation: Jackson State University, Department of Biochemistry and Chemistry, PO Box 17910 Jackson, MS USA ; Tunceli University, Faculty of Engineering, Department of Bioengineering, Tunceli, 62000, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Ates
authors.affiliation: Jackson State University, Molecular Toxicology Research Laboratory, P.O. Box 18540, Jackson, MS USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Dugo
authors.affiliation: Tunceli University, Faculty of Engineering, Department of Bioengineering, Tunceli, 62000, Turkey.
authors.forename: V
authors.initials: V
authors.lastname: Demir
authors.affiliation: Jackson State University, Department of Biochemistry and Chemistry, PO Box 17910 Jackson, MS USA.
authors.forename: Z
authors.initials: Z
authors.lastname: Arslan
authors.affiliation: Jackson State University, Molecular Toxicology Research Laboratory, P.O. Box 18540, Jackson, MS USA.
authors.forename: P B
authors.initials: PB
authors.lastname: Tchounwou
keywords: Accumulation; CuO; Nanoparticles; Oxidative Stress; Sheepshead Minnow