title: Spectrum of sleep disorders in a patient with spinocerebellar ataxia 13.
abstract: We report the case of a 52-year-old female with spinocerebellar ataxia (SCA) 13. She presented with complaints of insomnia and had a history of restless legs syndrome. Her polysomnogram revealed that she had a significantly elevated periodic limb movement index, mild obstructive sleep apnea, and the absence of REM sleep. Sleep disorders have previously been described in patients with SCA 1, SCA 2, SCA 3, and SCA 6. To our knowledge, this is the first description of sleep disorders in a patient with SCA 13.
authors.affiliation: Dartmouth Hitchcock Medical Center, Sleep Disorders Center, Lebanon, NH.
authors.forename: Mukesh
authors.initials: M
authors.lastname: Kapoor
authors.affiliation: Dartmouth Hitchcock Medical Center, Sleep Disorders Center, Lebanon, NH.
authors.forename: Glen
authors.initials: G
authors.lastname: Greenough
mesh_terms: D052160:Benzothiazoles / Q000627:therapeutic use; D018491:Dopamine Agonists / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D017286:Polysomnography; D000077487:Pramipexole; D012148:Restless Legs Syndrome / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D020181:Sleep Apnea, Obstructive / Q000150:complications / Q000175:diagnosis; D007319:Sleep Initiation and Maintenance Disorders / Q000150:complications / Q000175:diagnosis; D012893:Sleep Wake Disorders / Q000150:complications* / Q000175:diagnosis*; D020754:Spinocerebellar Ataxias / Q000151:congenital; D013132:Spinocerebellar Degenerations / Q000150:complications*
chemical_list: D052160:Benzothiazoles; D018491:Dopamine Agonists; D000077487:Pramipexole