title: Mixed adenocarcinoma and neuroendocrine prostate cancer: a case report.
abstract: BACKGROUND
  Neuroendocrine prostate cancer is rare but lethal. It is one of the most common extra pulmonary manifestations of small cell cancer.
  
  
  METHODS
  Here we present a case report of a 53-year-old male who presents with a mixed adenocarcinoma and neuroendocrine prostate tumor on a background of previously normal prostate-specific antigen (PSA). His initial symptoms prior to diagnosis included decreased urine output and acute kidney injury (AKI).
  
  
  CONCLUSIONS
  Neuroendocrine tumor does not elevate the PSA level and hence is often a late finding with a poor prognosis. Special staining on histopathogy is required to reveal this diagnosis.
authors.affiliation: Department of Medicine, Reading Health System, West Reading, PA, USA.
authors.forename: Rittu
authors.initials: R
authors.lastname: Hingorani
authors.affiliation: Department of Medicine, Reading Health System, West Reading, PA, USA.
authors.forename: Jessica
authors.initials: J
authors.lastname: Young
authors.affiliation: Department of Medicine, Reading Health System, West Reading, PA, USA; Jefferson Medical College, Philadelphia, PA, USA; Richard.Alweis@readinghealth.org.
authors.forename: Richard
authors.initials: R
authors.lastname: Alweis
keywords: neuroendocrine; prostate cancer; prostate specific antigen