title: Kinesia paradoxa: a challenging Parkinson's phenomenon for simulation.
abstract: The present work aims to study extensively the literature on the phenomenon of "kinesia paradoxa" presented in Parkinson's disease patients, who generally cannot move but under certain circumstances exhibit a sudden, brief period of mobility (walking or even running). The objective of this study was to identify the mechanisms causing this phenomenon and relate them with respectively computational simulations aiming to draw attention to gaps and weaknesses and possible directions for future research. The study of this phenomenon with the use of modeling techniques may be a decisive factor for its interpretation.
authors.affiliation: Department of Informatics, Ionian University, 7 Tsirigoti Square, Corfu, Greece, irene.banou@gmail.com.
authors.forename: Eirini
authors.initials: E
authors.lastname: Banou
mesh_terms: D000313:Adrenal Medulla / Q000187:drug effects / Q000503:physiopathology; D000978:Antiparkinson Agents / Q000627:therapeutic use; D001479:Basal Ganglia / Q000187:drug effects / Q000503:physiopathology; D002531:Cerebellum / Q000187:drug effects / Q000503:physiopathology; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D008959:Models, Neurological; D010300:Parkinson Disease / Q000188:drug therapy / Q000503:physiopathology* / Q000523:psychology; D010829:Physiological Phenomena / Q000502:physiology*; D012420:Running / Q000502:physiology*; D013315:Stress, Psychological / Q000503:physiopathology / Q000523:psychology; D016138:Walking / Q000502:physiology*
chemical_list: D000978:Antiparkinson Agents; D007980:Levodopa