title: Mild hyponatremia is a common finding in children evaluated at the emergency department and it is significantly related to plasma C-reactive protein value.
abstract: OBJECTIVE
  During infectious diseases, mild hyponatremia is supposed to derive from a transient secretion of vasopressin mediated by non--osmotic stimuli. This study provides data supporting that mild hyponatremia during acute illnesses is related to the systemic inflammatory condition.
  
  
  METHODS
  I retrospectively analyzed 328 consecutive children (aged 3 months to 17 years) who received blood tests at the pediatric emergency department in 2 months' period.
  
  
  RESULTS
  hyponatremia was found in 98 patients, most of them being mildly hyponatremic. A significant trend towards lower levels of plasmatic sodium, paralleling the increase of C--reactive protein, was showed.
  
  
  CONCLUSIONS
  A significant relationship between plasmatic sodium levels and C--reactive protein was found, apart from the underlying disease.
authors.affiliation: Department of Pediatrics, Azienda Ospedaliera di Melegnano, Vizzolo Predabissi (MI) - dimimedpv@yahoo.it.
authors.forename: D
authors.initials: D
authors.lastname: Poddighe