title: Dramatic response to itraconazole in central nervous system aspergillosis complicating acute promyelocytic leukemia.
abstract: Abstract Fungal infection is a rare complication of acute leukemia, in which a combination of voriconazole and amphotericin B is a first-line regimen of treatment. Here administration of itraconazole plus caspofungin resulted in a dramatic response in a patient with acute promyelocytic leukemia (APL).
authors.affiliation: From the Department of Hematology, Second Xiang-ya Hospital, Central South University , Changsha, Hunan , P. R. China.
authors.forename: Hong-Ling
authors.initials: HL
authors.lastname: Peng
authors.forename: Yi-Fang
authors.initials: YF
authors.lastname: Yi
authors.forename: Xiao-Hui
authors.initials: XH
authors.lastname: Shen
authors.forename: Ya-Fei
authors.initials: YF
authors.lastname: Yin
authors.forename: Guang-Sen
authors.initials: GS
authors.lastname: Zhang
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use*; D001228:Aspergillosis / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use*; D015473:Leukemia, Promyelocytic, Acute / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole