title: Using SomaticSniper to Detect Somatic Single Nucleotide Variants.
abstract: Detecting somatic single nucleotide variants (SNVs) is an essential component of cancer research with next generation sequencing data. This protocol describes how to run the SomaticSniper somatic SNV detector and then filter the output to eliminate most false positives. It also includes support protocols detailing the compilation of the software.
authors.affiliation: The Genome Institute at Washington University, St. Louis, Missouri.
authors.forename: David E
authors.initials: DE
authors.lastname: Larson
authors.affiliation: The Genome Institute at Washington University, St. Louis, Missouri.
authors.forename: Travis E
authors.initials: TE
authors.lastname: Abbott
authors.affiliation: The Genome Institute at Washington University, St. Louis, Missouri.
authors.forename: Richard K
authors.initials: RK
authors.lastname: Wilson
mesh_terms: D019295:Computational Biology; D020407:Internet; D020641:Polymorphism, Single Nucleotide
keywords: next-generation sequencing; somatic variant calling; somaticsniper