title: Predictive factors for intrauterine growth restriction.
abstract: Reduced fetal growth is seen in about 10% of the pregnancies but only a minority has a pathological background and is known as intrauterine growth restriction or fetal growth restriction (IUGR / FGR). Increased fetal and neonatal mortality and morbidity as well as adult pathologic conditions are often associated to IUGR. Risk factors for IUGR are easy to assess but have poor predictive value. For the diagnostic purpose, biochemical serum markers, ultrasound and Doppler study of uterine and spiral arteries, placental volume and vascularization, first trimester growth pattern are object of assessment today. Modern evaluations propose combined algorithms using these strategies, all with the goal of a better prediction of risk pregnancies.
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania University Emergency Hospital Bucharest Obstetrics and Gynecology Unit.
authors.forename: A R
authors.initials: AR
authors.lastname: Albu
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania University Emergency Hospital Bucharest Obstetrics and Gynecology Unit.
authors.forename: A F
authors.initials: AF
authors.lastname: Anca
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania University Emergency Hospital Bucharest Obstetrics and Gynecology Unit.
authors.forename: V V
authors.initials: VV
authors.lastname: Horhoianu
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania University Emergency Hospital Bucharest Obstetrics and Gynecology Unit.
authors.forename: I A
authors.initials: IA
authors.lastname: Horhoianu
mesh_terms: D000328:Adult; D000465:Algorithms; D015415:Biomarkers / Q000097:blood*; D005260:Female; D047109:Fetal Development / Q000502:physiology*; D005317:Fetal Growth Retardation / Q000175:diagnosis* / Q000453:epidemiology*; D006801:Humans; D010920:Placenta / Q000033:anatomy & histology* / Q000098:blood supply; D011237:Predictive Value of Tests; D011247:Pregnancy; D012307:Risk Factors; D018608:Ultrasonography, Doppler / Q000379:methods
chemical_list: D015415:Biomarkers
keywords: PAPP-A; high-risk pregnancy; intrauterine growth restriction; serum markers; uterine artery Doppler