title: Strain-blood pressure index for evaluation of early changes in elasticity of anterior tibial artery in patients with type 2 diabetes mellitus.
abstract: BACKGROUND
  The aim of this study was to investigate the feasibility and value of strain-blood pressure index (SBPI) to assess early changes in elasticity of anterior tibial artery in patients with type 2 diabetes mellitus (T2DM).
  
  
  METHODS
  Eighty-one randomly selected in-patients with T2DM were divided into 2 groups--a vascular complication negative group (n=42) and a vascular complication positive group (n=39). Forty healthy volunteers were enrolled in a control group. Ultrasonographic scans using Xstrain™ technique were conducted for every patient to obtain the maximum circumferential strain (CSmax) of anterior tibial artery; patient blood pressure was also measured for calculating strain-blood pressure index (SBPI=CSmax/[(local pulse pressure)/local diastolic blood pressure] ×100%. Afterwards, SBPIs of various groups were comparatively analyzed.
  
  
  RESULTS
  Differences in SBPIs among the 3 groups were statistically significant (control group > negative group > positive group, P<0.05).
  
  
  CONCLUSIONS
  SBPI could be used as a new indicator for the evaluation on the anterior tibial arterial elasticity of T2DM patients and it was able to reflect the early elasticity changes in anterior tibial arteries in T2DM patients with atherosclerosis.
authors.affiliation: Department of Ultrasonic Diagnosis, Second Affiliated Hospital & Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China (mainland).
authors.forename: Chunpeng
authors.initials: C
authors.lastname: Zou
authors.affiliation: Department of Obstetrics and Gynecology Ultrasonic, Wenzhou City Peoples' Hospital, Wenzhou, China (mainland).
authors.forename: Yan
authors.initials: Y
authors.lastname: Jiao
authors.affiliation: Department of Endocrinology, Second Affiliated Hospital & Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China (mainland).
authors.forename: Chao
authors.initials: C
authors.lastname: Zheng
authors.affiliation: Department of Ultrasonic Diagnosis, Second Affiliated Hospital & Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China (mainland).
authors.forename: Yaping
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Department of Anesthesiology, Second Affiliated Hospital & Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China (mainland).
authors.forename: Xingwang
authors.initials: X
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000503:physiopathology*; D004548:Elasticity; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016909:Tibial Arteries / Q000503:physiopathology*; D017539:Tunica Intima / Q000000981:diagnostic imaging / Q000503:physiopathology; D014463:Ultrasonography