title: Branch-type intraductal papillary mucinous neoplasm of the pancreas: clinically and patient-reported outcomes.
abstract: OBJECTIVE
  The majority of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas are branch duct (BD) IPMNs, and these neoplasms are being diagnosed with increasing frequency; no data are also available on the well-being (quality of life [QoL]) of these patients. We aimed to evaluate the 2-year follow-up results in consecutive patients with BD-IPMNs to assess symptoms at presentation and their morphological progression; the physical and psychological statuses of these patients were also evaluated.
  
  
  METHODS
  One hundred one patients with BD-IPMN of the pancreas were enrolled in the study (37.6% men and 62.4% women; mean [SD] age, 66.3 [10.4] years). Magnetic resonance imaging was used to evaluate the modification of the cystic lesions at baseline as well as in the follow-up. The SF-12 Health Survey, the State-Trait Anxiety Inventory Y-1 and Y-2, the 12-Item General Health Questionnaire, as well as the Beck Depression Inventory-II were used to evaluate the QoL once a year.
  
  
  RESULTS
  The mean (SD) basal size of the major lesion was 15.5 (8.9) mm, and in the follow-up period, the size remained stable. The QoL did not change during the follow-up period.
  
  
  CONCLUSIONS
  Branch duct IPMNs are very slow-growing neoplasms, and they do not affect the QoL of affected patients.
authors.affiliation: From the *Pancreas Unit, Department of Digestive Diseases and Internal Medicine, and †Department of Radiology, Sant'Orsola-Malpighi Hospital, Bologna, Italy.
authors.forename: Raffaele
authors.initials: R
authors.lastname: Pezzilli
authors.forename: Lucia
authors.initials: L
authors.lastname: Calculli
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018450:Disease Progression; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018297:Neoplasms, Cystic, Mucinous, and Serous / Q000473:pathology* / Q000523:psychology* / Q000628:therapy; D010183:Pancreatic Ducts / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000473:pathology* / Q000523:psychology* / Q000628:therapy; D011379:Prognosis; D011446:Prospective Studies; D011788:Quality of Life; D011795:Surveys and Questionnaires; D013997:Time Factors; D047368:Tumor Burden