title: Choline phosphate functionalized surface: protein-resistant but cell-adhesive zwitterionic surface potential for tissue engineering.
abstract: A choline phosphate (CP) modified surface is designed to resist protein adsorption due to its zwitterionic properties and simultaneously promote cell adhesion though its universal interaction with phosphate choline (PC) headgroups of the cell membrane. This work provides a new approach to obtain a cell-adhesive surface with a non-biofouling 'background', which has a potential for tissue engineering.
authors.affiliation: College of Polymer Science and Engineering, Sichuan University, Chengdu 610065, China. jianshu_li@scu.edu.cn.
authors.forename: Xingyu
authors.initials: X
authors.lastname: Chen
authors.forename: Tianchan
authors.initials: T
authors.lastname: Chen
authors.forename: Zaifu
authors.initials: Z
authors.lastname: Lin
authors.forename: Xian'e
authors.initials: X
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Wu
authors.forename: Jianshu
authors.initials: J
authors.lastname: Li
mesh_terms: D026921:Amino Acid Transport Systems, Neutral / Q000737:chemistry*; D002448:Cell Adhesion; D002462:Cell Membrane / Q000737:chemistry; D057927:Hydrophobic and Hydrophilic Interactions; D018613:Microscopy, Confocal; D010767:Phosphorylcholine / Q000737:chemistry*; D013499:Surface Properties; D023822:Tissue Engineering
chemical_list: D026921:Amino Acid Transport Systems, Neutral; D010767:Phosphorylcholine