title: Morning glory syndrome associated with multiple sclerosis.
abstract: Morning glory syndrome (MGS) is a rare congenital optic disc anomaly characterized by a funnel-shaped, excavated optic disc surrounded by chorioretinal pigmentary disturbance. The main ophthalomoscopic feature of the MGS is enlarged optic disc with a funnel shaped scleral defect; elevated peripapillary chorioretinal pigmentation; and pale fluffy tissue of glial hyperplasia overlying the optic disc. Although most of the reported cases were isolated ocular abnormality, but it may occurs in association with other ophthalmic abnormalities such as cyst of the optic nerve atrophy, congenital cataract, microophthalmos, and aniridia. Craniofacial deformities such as cleft lip and palate, hypertelorism, dysplatic ears; renal abnormalities; and cardiac defects have also been reported with MGS. Herein, we present a case of MGS associated with multiple sclerosis - a rather unusual concurrence.
authors.affiliation: Clinical Neurology Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Anahid
authors.initials: A
authors.lastname: Safari
authors.affiliation: Department of Ophthalmology, Division of Corneal Disease, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Esmail
authors.initials: E
authors.lastname: Jafari
authors.affiliation: Department of Neurology, School of Medicine AND Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Afshin
authors.initials: A
authors.lastname: Borhani-Haghighi
keywords: Demyelinative Disorders; Morning Glory Disc Anomaly; Morning Glory Syndrome; Multiple Sclerosis; Optic Neuritis