title: Understanding and harnessing hydrogenases, biological dihydrogen catalysts.
abstract: It has been estimated that 99 % of all organisms utilize dihydrogen (H2). Most of these species are microbes and their ability to use H₂as a metabolite arises from the expression of H2 metalloenzymes known as hydrogenases. These molecules have been the focus of intense biological, biochemical, and chemical research because hydrogenases are biotechnologically relevant enzymes.
authors.affiliation: Department of Chemistry, University of York, Heslington, York, YO10 5DD, UK, alison.parkin@york.ac.uk.
authors.forename: Alison
authors.initials: A
authors.lastname: Parkin
mesh_terms: D000818:Animals; D002384:Catalysis; D003246:Conservation of Energy Resources / Q000379:methods*; D006801:Humans; D006859:Hydrogen / Q000737:chemistry*; D006864:Hydrogenase / Q000737:chemistry / Q000378:metabolism*; D007501:Iron / Q000737:chemistry; D060847:Metabolic Engineering / Q000379:methods; D059013:Microbial Consortia; D009532:Nickel / Q000737:chemistry; D010084:Oxidation-Reduction; D012993:Solar Energy
chemical_list: D009532:Nickel; D006859:Hydrogen; D007501:Iron; C058560:nickel-iron-selenium hydrogenase; D006864:Hydrogenase