title: Breast cancer prevention.
abstract: Breast cancer is the most common cancer in women with 232,670 new cases estimated in the USA for 2014. Approaches for reducing breast cancer risk include lifestyle modification, chemoprevention, and prophylactic surgery. Lifestyle modification has a variety of health benefits with few associated risks and is appropriate for all women regardless of breast cancer risk. Chemoprevention options have expanded rapidly, but most are directed at estrogen receptor positive breast cancer and uptake is low. Prophylactic surgery introduces significant additional risks of its own and is generally reserved for the highest risk women.
authors.affiliation: Department of Surgery, Johns Hopkins Hospital, Baltimore, Maryland.
authors.forename: David M
authors.initials: DM
authors.lastname: Euhus
authors.forename: Jennifer
authors.initials: J
authors.lastname: Diaz
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D047072:Aromatase Inhibitors / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000517:prevention & control*; D018890:Chemoprevention; D005260:Female; D015438:Health Behavior; D006801:Humans; D008019:Life Style; D008408:Mastectomy; D065286:Prophylactic Surgical Procedures; D018570:Risk Assessment; D012307:Risk Factors; D020845:Selective Estrogen Receptor Modulators / Q000627:therapeutic use; D013629:Tamoxifen / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D047072:Aromatase Inhibitors; D020845:Selective Estrogen Receptor Modulators; D013629:Tamoxifen
keywords: breast neoplasms; chemoprevention; lifestyle; prophylactic surgery; tamoxifen