title: Plasmonic metal scattering immunoassay by total internal reflection scattering microscopy with nanoscale lateral resolution.
abstract: Immunoassays on nanopatterned chips through TIRS detection based on reconstructing the three dimensional position provided a nanoscale accuracy of the lateral resolution by using the z-stage controller in the spatial range up to 10 nm. This method offers highly accurate and sensitive quantification with the zeptomolar (∼10(-21) M) detection of proteins.
authors.affiliation: Department of Applied Chemistry, Kyung Hee University, Yongin-si, Gyeonggi-do 446-701, Republic of Korea. shkang@khu.ac.kr.
authors.forename: Seungah
authors.initials: S
authors.lastname: Lee
authors.forename: Hyunung
authors.initials: H
authors.lastname: Yu
authors.forename: Seong Ho
authors.initials: SH
authors.lastname: Kang
mesh_terms: D006801:Humans; D007118:Immunoassay / Q000379:methods*; D008027:Light; D008670:Metals; D008853:Microscopy; D036103:Nanotechnology / Q000379:methods*; D012542:Scattering, Radiation
chemical_list: D008670:Metals