title: Refractive index dependent real-time plasmonic nanoprobes on a single silver nanocube for ultrasensitive detection of the lung cancer-associated miRNAs.
abstract: We developed a novel method for the real-time monitoring of the delicate change in refractive index (RI) when DNA or RNA hybridize near a DNA-capped silver nanocube (AgNC) surface. This method offers an alternative platform in the quantitative analysis of the trace lung cancer-associated miRNAs in label-free detection.
authors.affiliation: Key Laboratory for Organic Electronics and Information Displays & Institute of Advanced Materials (IAM), National Synergistic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China. iamlhwang@njupt.edu.cn.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yanling
authors.initials: Y
authors.lastname: Hu
authors.forename: Quli
authors.initials: Q
authors.lastname: Fan
authors.forename: Wenjing
authors.initials: W
authors.lastname: Yang
authors.forename: Anran
authors.initials: A
authors.lastname: Li
authors.forename: Shuzhou
authors.initials: S
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Huang
authors.forename: Lianhui
authors.initials: L
authors.lastname: Wang
mesh_terms: D001483:Base Sequence; D015374:Biosensing Techniques / Q000379:methods*; D004277:DNA, Single-Stranded / Q000737:chemistry; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis*; D053768:Metal Nanoparticles / Q000737:chemistry*; D035683:MicroRNAs / Q000032:analysis*; D012031:Refractometry / Q000379:methods*; D012680:Sensitivity and Specificity; D012834:Silver / Q000737:chemistry*
chemical_list: D004277:DNA, Single-Stranded; C524940:MIRN21 microRNA, human; D035683:MicroRNAs; D012834:Silver