title: Mediastinal follicular dendritic cell sarcoma with paraneoplastic pemphigus.
abstract: Follicular dendritic cell sarcoma is a rare neoplasm of immune accessory cells. It occurs primarily in lymph nodes. Occurrences in the mediastinum are rarely reported. Diagnosis and management of follicular dendritic cell sarcoma remain unclear, and it is an under-recognized clinical entity. Only a few cases of paraneoplastic pemphigus as the first presentation of follicular dendritic cell sarcoma have been reported. We report an unusual case of follicular dendritic cell sarcoma of the anterior mediastinum, presenting as paraneoplastic pemphigus in a 62-year-old man. Typical histological features confirmed the diagnosis of follicular dendritic cell sarcoma, and surgical resection was successfully performed.
authors.affiliation: Division of Cardiothoracic Surgery, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong.
authors.forename: Simon C Y
authors.initials: SC
authors.lastname: Chow
authors.affiliation: Division of Cardiothoracic Surgery, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong eugene.cts@gmail.com.
authors.forename: Eugene C L
authors.initials: EC
authors.lastname: Yeung
authors.affiliation: Division of Cardiothoracic Surgery, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong.
authors.forename: Calvin S H
authors.initials: CS
authors.lastname: Ng
authors.affiliation: Division of Cardiothoracic Surgery, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong.
authors.forename: Randolph H L
authors.initials: RH
authors.lastname: Wong
authors.affiliation: Department of Anatomical & Cellular Pathology, The Chinese University of Hong Kong, Hong Kong.
authors.forename: Ka
authors.initials: K
authors.lastname: Fai To
authors.affiliation: Division of Cardiothoracic Surgery, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong.
authors.forename: Innes Y P
authors.initials: IY
authors.lastname: Wan
mesh_terms: D054740:Dendritic Cell Sarcoma, Follicular / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D008482:Mediastinum / Q000000981:diagnostic imaging / Q000601:surgery; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D010392:Pemphigus / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D049268:Positron-Emission Tomography; D016896:Treatment Outcome
keywords: Dendritic cell sarcoma; follicular; mediastinal neoplasms; paraneoplastic syndromes; pemphigus