title: Extraneural Metastases of Glioblastoma without Simultaneous Central Nervous System Recurrence.
abstract: Glioblastoma multiforme (GBM) is well known as the most common malignant primary brain tumor. It could easily spread into the adjacent or distant brain tissue by infiltration, direct extension and cerebro-spinal fluid dissemination. The extranueural metastatic spread of GBM is relatively rare but it could have more progressive disease course. We report a 39-year-old man who had multiple bone metastases and malignant pleural effusion of the GBM without primary site recurrence.
authors.affiliation: Department of Neurosurgery, Seoul National University Hospital, Seoul, Korea.
authors.forename: Wonki
authors.initials: W
authors.lastname: Kim
authors.affiliation: Neuro-Oncology Clinic, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
authors.forename: Heon
authors.initials: H
authors.lastname: Yoo
authors.affiliation: Neuro-Oncology Clinic, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
authors.forename: Sang Hoon
authors.initials: SH
authors.lastname: Shin
authors.affiliation: Neuro-Oncology Clinic, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
authors.forename: Ho Shin
authors.initials: HS
authors.lastname: Gwak
authors.affiliation: Neuro-Oncology Clinic, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
authors.forename: Seung Hoon
authors.initials: SH
authors.lastname: Lee
keywords: Glioblastoma multiforme; Malignant; Neoplasm metastasis; Pleural effusion; Spinal neoplasms