title: [Two cases of severe pruritus revealing Hodgkin's disease in children].
abstract: BACKGROUND
  Pruritus in children is a frequent reason for consultation, most often related to a common dermatosis. Where dermatological investigation fails to reveal a dermatological cause, a general cause may be suspected. We report three cases of pruritus revealing Hodgkin's lymphoma in children.
  
  
  METHODS
  Case 1: a 14-year-old girl presented pruritus with diffuse scratching lesions present for 6 months, associated with right cervical lymph nodes occurring after the onset of pruritus. Tomodensitometry revealed involvement of the supra- and sub-diaphragmatic lymph nodes as well as pulmonary involvement. Lymph node biopsy confirmed nodular sclerosing Hodgkin's lymphoma. Case 2: a 14-year-old boy was hospitalized for suspected psychogenic pruritus. He presented intense itching, predominantly in the lower extremities and at night, occurring over the previous 6 months as well as night sweats. Examination showed that the patient had lost 5kg in 1 month and had a low-grade fever of 38°C; he presented linear striated scratching lesions on both legs. Cervical and inguinal lymphadenopathy was seen. The chest scan also revealed supra-diaphragmatic adenomegalies. The biopsy confirmed Hodgkin's lymphoma.
  
  
  CONCLUSIONS
  Systemic causes of pruritus in children are poorly described in the literature. In these two cases, pruritus allowed a diagnosis of Hodgkin's lymphoma to be made, emphasizing the important role of dermatologists in the early diagnosis of haematological malignancy.
authors.affiliation: Services de dermatologie et de médecine vasculaire, centre hospitalier Victor-Dupouy, 69, rue du Lieutenant-Colonel-Prud'hon, 95107 Argenteuil cedex, France. Electronic address: maud.amydelabreteque@ch-argenteuil.fr.
authors.forename: M
authors.initials: M
authors.lastname: Amy de la Bretèque
authors.affiliation: Services de dermatologie et de médecine vasculaire, centre hospitalier Victor-Dupouy, 69, rue du Lieutenant-Colonel-Prud'hon, 95107 Argenteuil cedex, France.
authors.forename: P
authors.initials: P
authors.lastname: Bilan
authors.affiliation: Services de dermatologie et de médecine vasculaire, centre hospitalier Victor-Dupouy, 69, rue du Lieutenant-Colonel-Prud'hon, 95107 Argenteuil cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Galesowski
authors.affiliation: Service de pédiatrie, hôpital Ambroise-Paré, Assistance publique-Hôpitaux de Paris, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France.
authors.forename: B
authors.initials: B
authors.lastname: Chevallier
authors.affiliation: Cabinet de dermatologie, 95100 Argenteuil, France.
authors.forename: D
authors.initials: D
authors.lastname: Drouot
authors.affiliation: Services de dermatologie et de médecine vasculaire, centre hospitalier Victor-Dupouy, 69, rue du Lieutenant-Colonel-Prud'hon, 95107 Argenteuil cedex, France.
authors.forename: M-L
authors.initials: ML
authors.lastname: Sigal
authors.affiliation: Services de dermatologie et de médecine vasculaire, centre hospitalier Victor-Dupouy, 69, rue du Lieutenant-Colonel-Prud'hon, 95107 Argenteuil cedex, France.
authors.forename: E
authors.initials: E
authors.lastname: Mahé
mesh_terms: D000293:Adolescent; D057210:Delayed Diagnosis; D003951:Diagnostic Errors; D005260:Female; D006689:Hodgkin Disease / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D011537:Pruritus / Q000209:etiology*; D011602:Psychophysiologic Disorders / Q000175:diagnosis; D013546:Sweating
keywords: Adolescent; Child; Enfant; Hodgkin's disease; Lymphoma; Lymphome; Maladie de Hodgkin; Prurit; Pruritus