title: Large chondrosarcoma of the lumbar spine--a rare yet important cause of lower back pain.
abstract: We report a case of a large chondrosarcoma of an L4 vertebral body causing iliac vein thrombosis. The slow-growing tumor eluded definitive diagnosis early in its development since the main symptom it caused was only lower back pain. Five years after onset of the disease, the patient presented with fever, tenderness and swelling in the leg, the tumor was diagnosed and found to be exerting a mass effect causing further pain and compressing the left common iliac vein. Due to inoperability of the tumor, a multidisciplinary surgical approach was used to resect the majority of the tumor as apalliative measure and rid the patient of her symptoms. Due to the chemoresistance and relative radioresistance of these tumors, prompt full surgical resection before the tumor invades vital structures remains the mainstay of successful treatment of chondrosarcoma of the spine.
authors.forename: Miljenko
authors.initials: M
authors.lastname: Franić
authors.forename: Stjepan
authors.initials: S
authors.lastname: Dokuzović
authors.forename: Srećko
authors.initials: S
authors.lastname: Marušić
authors.forename: Vladimir
authors.initials: V
authors.lastname: Kovaĉ
mesh_terms: D002813:Chondrosarcoma / Q000150:complications*; D005260:Female; D006801:Humans; D017116:Low Back Pain / Q000209:etiology; D008159:Lumbar Vertebrae; D008875:Middle Aged; D013125:Spinal Neoplasms / Q000150:complications*