title: Relationship of high blood lactate levels with latency of visual-evoked potentials.
abstract: We studied, in healthy adult subjects, the association of high blood lactate levels, induced with an exhaustive exercise (12 subjects) or an intravenous infusion (four subjects) of a lactate solution (3 mg/kg in 1 min), with amplitude and latency of visual-evoked potentials. Amplitude of N75, P100, and N145 components did not show significant changes, whereas latency of P100 was reduced at exercise's end and that of N145 increased 10 min after the conclusion. Therefore, an increase of blood lactate induced by an exhaustive exercise or an intravenous infusion appears to induce an improvement in the conduction time between eye and striate cortex, while it seems to evoke a worsening of intracortical communication between striate and extrastriate areas.
authors.affiliation: Department of Bio-Medical Sciences, Section of Physiology, University of Catania, Catania, Italy.
authors.forename: Marinella
authors.initials: M
authors.lastname: Coco
authors.forename: Giovanna
authors.initials: G
authors.lastname: Alagona
authors.forename: Giulia
authors.initials: G
authors.lastname: De Maria
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Rapisarda
authors.forename: Erminio
authors.initials: E
authors.lastname: Costanzo
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Perciavalle
authors.forename: Valentina
authors.initials: V
authors.lastname: Perciavalle
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001786:Blood Glucose; D004569:Electroencephalography; D005074:Evoked Potentials, Visual / Q000187:drug effects / Q000502:physiology*; D015444:Exercise / Q000502:physiology; D005260:Female; D006801:Humans; D019344:Lactic Acid / Q000097:blood* / Q000494:pharmacology; D008297:Male; D010775:Photic Stimulation; D011601:Psychophysics; D011930:Reaction Time / Q000502:physiology*; D013997:Time Factors; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D019344:Lactic Acid