title: DB-AT: a 2015 update to the Full-parasites database brings a multitude of new transcriptomic data for apicomplexan parasites.
abstract: The previous release of our Full-parasites database (http://fullmal.hgc.jp/) brought enhanced functionality, an expanded full-length cDNA content, and new RNA-Seq datasets from several important apicomplexan parasites. The 2015 update witnesses the major shift in the databases content with focus on diverse transcriptomes of the apicomplexan parasites. The content of the database was substantially enriched with transcriptome information for new apicomplexan parasites. The latest version covers a total of 17 species, with addition of our newly generated RNA-Seq data of a total of 909,150,388 tags. Moreover, we have generated and included two novel and unique datasets, which represent diverse nature of transcriptomes in individual parasites in vivo and in vitro. One is the data collected from 116 Indonesian patients infected with Plasmodium falciparum. The other is a series of transcriptome data collected from a total of 38 single cells of P. falciparum cultured in vitro. We believe that with the recent advances our database becomes an even better resource and a unique platform in the analysis of apicomplexan parasites and their interaction with their hosts. To adequately reflect the recent modifications and the current content we have changed the database name to DB-AT--DataBase of Apicomplexa Transcriptomes.
authors.affiliation: University of Münster, Faculty of Medicine, Institute of Bioinformatics, Niels-Stensen Strasse 14, 48149 Münster, Germany.
authors.forename: Marcin
authors.initials: M
authors.lastname: Jąkalski
authors.affiliation: Department of Medical Genome Science, Room 032, Sougou Research Complex, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8562, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Wakaguri
authors.affiliation: University of Münster, Faculty of Medicine, Institute of Bioinformatics, Niels-Stensen Strasse 14, 48149 Münster, Germany.
authors.forename: Tabea G
authors.initials: TG
authors.lastname: Kischka
authors.affiliation: National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan.
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Nishikawa
authors.affiliation: National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan.
authors.forename: Shin-ichiro
authors.initials: S
authors.lastname: Kawazu
authors.affiliation: National Institute of Animal Health, National Agricultural and Food Research Organization, Kannondai, Tsukuba, Ibaraki 305-0856, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Matsubayashi
authors.affiliation: Nippon Institute for Biological Science, 9-2221-1 Shin-machi, Ome, Tokyo 198-0024, Japan.
authors.forename: Fumiya
authors.initials: F
authors.lastname: Kawahara
authors.affiliation: Department of Parasitology, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0374, Japan.
authors.forename: Naotoshi
authors.initials: N
authors.lastname: Tsuji
authors.affiliation: National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan.
authors.forename: Shinuo
authors.initials: S
authors.lastname: Cao
authors.affiliation: School of Veterinary Medicine, Azabu University, 1-17-71 Fucinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan.
authors.forename: Fujiko
authors.initials: F
authors.lastname: Sunaga
authors.affiliation: National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan.
authors.forename: Xuenan
authors.initials: X
authors.lastname: Xuan
authors.affiliation: National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan.
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Okubo
authors.affiliation: National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan.
authors.forename: Ikuo
authors.initials: I
authors.lastname: Igarashi
authors.affiliation: Department of Medicine, Sam Ratulangi University, Kampus Unsrat, Bahu Manado, 95115, Indonesia.
authors.forename: Josef
authors.initials: J
authors.lastname: Tuda
authors.affiliation: Department of Medicine, Sam Ratulangi University, Kampus Unsrat, Bahu Manado, 95115, Indonesia.
authors.forename: Arthur E
authors.initials: AE
authors.lastname: Mongan
authors.affiliation: Oita University, School of Medicine, 1-1 Idaigaoka, Hazamacho, Yufu, Oita 879-5593, Japan.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Eshita
authors.affiliation: Obihiro University of Agriculture and Veterinary Medicine, Inada-cho West 2-13, Obihiro, Hokkaido 080-8555, Japan.
authors.forename: Ryuichiro
authors.initials: R
authors.lastname: Maeda
authors.affiliation: University of Münster, Faculty of Medicine, Institute of Bioinformatics, Niels-Stensen Strasse 14, 48149 Münster, Germany.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Makałowski
authors.affiliation: Department of Medical Genome Science, Room 032, Sougou Research Complex, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8562, Japan junya@czc.hokudai.ac.jp.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Suzuki
authors.affiliation: Division of Collaboration and Education, Research Center for Zoonosis Control, Hokkaido University, North 20, West 10 Kita-ku, Sapporo, Hokkaido 001-0020, Japan Global Station for Zoonosis Control, GI-CoRE, Hokkaido University, North 20, West 10 Kita-ku, Sapporo, Hokkaido 001-0020, Japan junya@czc.hokudai.ac.jp.
authors.forename: Junya
authors.initials: J
authors.lastname: Yamagishi
mesh_terms: D016782:Apicomplexa / Q000235:genetics*; D030541:Databases, Genetic; D020869:Gene Expression Profiling; D006801:Humans; D020407:Internet; D016778:Malaria, Falciparum / Q000469:parasitology; D010963:Plasmodium falciparum / Q000235:genetics; D017423:Sequence Analysis, RNA