title: Up to date concepts about Von Willebrand disease and the diagnose of this hemostatic disorder.
abstract: The authors review the current data in literature regarding the recent knowledge about hemostase, coagulation and clinical and laboratory diagnostic algorithms of hemostatic disorders. They also present the pathological classification of bleeding disorders - the basis to clinical approach of these diseases.
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Bucharest.
authors.forename: I
authors.initials: I
authors.lastname: Buga-Corbu
authors.affiliation: "I. C. Fundeni" Pediatrics Clinic, "Carol Davila" University of Medicine and Pharmacy, Bucharest.
authors.forename: C
authors.initials: C
authors.lastname: Arion
mesh_terms: D001120:Arginine / Q000031:analogs & derivatives; D040461:Gene Components; D006487:Hemostasis / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D010875:Pipecolic Acids; D010973:Platelet Adhesiveness / Q000502:physiology; D010974:Platelet Aggregation / Q000502:physiology; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology*; D013449:Sulfonamides; D014842:von Willebrand Diseases / Q000145:classification* / Q000175:diagnosis* / Q000503:physiopathology*; D014841:von Willebrand Factor / Q000235:genetics / Q000378:metabolism*
chemical_list: D010875:Pipecolic Acids; D010975:Platelet Aggregation Inhibitors; D013449:Sulfonamides; D014841:von Willebrand Factor; D001120:Arginine; C031942:argatroban
keywords: diagnostic approach; hemostase; hemostatic disorders